GeneModel BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000622-TA|BGIBMGA000622-PA|IPR003599|Immunoglobulin
subtype, IPR003598|Immunoglobulin subtype 2, IPR000577|Carbohydrate
kinase, FGGY, IPR007110|Immunoglobulin-like, IPR013098|Immunoglobulin
I-set, IPR010939|Protein of unknown function DUF1136
         (4814 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein.             296   1e-78
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p...   294   4e-78
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.               294   4e-78
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.   294   4e-78
X90568-1|CAA62188.1|26926|Homo sapiens titin protein.                 293   8e-78
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr...   226   1e-57
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop...   226   1e-57
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop...   226   1e-57
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein.         226   1e-57
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr...   224   7e-57
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr...   222   3e-56
BC013867-1|AAH13867.2|  510|Homo sapiens PALLD protein protein.       206   1e-51
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein.           206   1e-51
AB023209-1|BAA76836.1|  772|Homo sapiens KIAA0992 protein protein.    206   1e-51
AF151909-1|AAD34146.1|  404|Homo sapiens CGI-151 protein protein.     196   1e-48
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly...   176   2e-42
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina...   175   2e-42
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina...   175   2e-42
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p...   171   4e-41
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase...   167   7e-40
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly...   167   7e-40
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain...   167   7e-40
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina...   167   7e-40
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.         155   4e-36
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p...   143   1e-32
BC005376-1|AAH05376.1|  498|Homo sapiens myotilin protein.            142   3e-32
AF144477-1|AAD44754.1|  498|Homo sapiens myotilin protein.            142   3e-32
AF133820-1|AAD29051.2|  498|Homo sapiens titin-like protein prot...   142   3e-32
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq...   129   2e-28
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq...   129   2e-28
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq...   129   2e-28
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq...   129   2e-28
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq...   129   2e-28
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq...   129   2e-28
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq...   129   2e-28
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq...   129   2e-28
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.          129   2e-28
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ...   124   6e-27
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal...   124   6e-27
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ...   124   6e-27
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.            124   6e-27
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.              124   1e-26
BC098579-1|AAH98579.1|  722|Homo sapiens PXDN protein protein.        124   1e-26
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant...   124   1e-26
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.     121   6e-26
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.     121   6e-26
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.    121   6e-26
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.                 121   7e-26
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere...   121   7e-26
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform...   120   1e-25
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform...   120   1e-25
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein.       120   1e-25
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ...   118   4e-25
AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein.            116   2e-24
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.           115   5e-24
AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein pr...   114   6e-24
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.       114   9e-24
BC039255-1|AAH39255.1|  617|Homo sapiens CNTN5 protein protein.       114   9e-24
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.              114   9e-24
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.               114   9e-24
AL163282-1|CAB90436.1|  812|Homo sapiens human CHD2-52 down synd...   112   3e-23
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe...   112   3e-23
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe...   112   3e-23
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe...   112   3e-23
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe...   112   3e-23
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe...   112   3e-23
BC070170-1|AAH70170.1|  637|Homo sapiens TTN protein protein.         111   8e-23
BC058824-1|AAH58824.1|  558|Homo sapiens TTN protein protein.         111   8e-23
BC013396-1|AAH13396.1|  305|Homo sapiens TTN protein protein.         111   8e-23
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.                 109   2e-22
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot...   107   7e-22
AK092284-1|BAC03850.1|  885|Homo sapiens protein ( Homo sapiens ...   106   2e-21
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.        105   3e-21
BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein pr...   105   5e-21
AK056336-1|BAB71154.1|  512|Homo sapiens protein ( Homo sapiens ...   105   5e-21
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.       104   9e-21
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.       104   9e-21
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.       104   9e-21
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein.    103   1e-20
AK128020-1|BAC87234.1|  595|Homo sapiens ursor.  protein.             102   3e-20
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.             100   1e-19
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr...    99   2e-19
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein.     99   3e-19
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1...    98   8e-19
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly...    97   1e-18
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein...    97   1e-18
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog...    97   1e-18
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog...    97   1e-18
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog...    97   1e-18
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ...    97   1e-18
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci...    97   2e-18
BX537391-1|CAD97633.1|  143|Homo sapiens hypothetical protein pr...    95   4e-18
BC067107-1|AAH67107.1|  814|Homo sapiens putative neuronal cell ...    95   4e-18
BC042054-1|AAH42054.1|  814|Homo sapiens putative neuronal cell ...    95   4e-18
DQ248309-1|ABB55264.1|  851|Homo sapiens rhabdomyosarcoma antige...    94   1e-17
AK074780-1|BAC11205.1|  570|Homo sapiens protein ( Homo sapiens ...    94   1e-17
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.               94   1e-17
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi...    94   1e-17
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot...    94   1e-17
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ...    94   1e-17
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ...    94   1e-17
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.             94   1e-17
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.     94   1e-17
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.      93   2e-17
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h...    93   2e-17
M32292-1|AAA35751.1|  750|Homo sapiens protein ( Human colorecta...    93   2e-17
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.     93   2e-17
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.               93   2e-17
AL360004-4|CAI16954.2|  746|Homo sapiens novel protein similar t...    93   3e-17
BC036524-1|AAH36524.1|  772|Homo sapiens DCC protein protein.          92   4e-17
AF058332-2|AAD22604.1|  926|Homo sapiens myocardium-specific tit...    92   4e-17
AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein.                92   4e-17
BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein ...    91   7e-17
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L...    91   7e-17
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro...    91   9e-17
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L...    91   9e-17
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole...    91   1e-16
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule...    91   1e-16
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1...    91   1e-16
DQ173642-2|ABC25979.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173641-2|ABC25974.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173640-2|ABC25969.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173639-2|ABC25964.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173638-2|ABC25959.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173637-2|ABC25954.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173636-2|ABC25949.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173635-2|ABC25944.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173634-2|ABC25939.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173633-2|ABC25934.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173632-2|ABC25929.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173631-2|ABC25924.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173630-2|ABC25919.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173629-2|ABC25914.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173628-2|ABC25909.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173627-2|ABC25904.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173626-2|ABC25899.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173625-2|ABC25894.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173624-2|ABC25889.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173623-2|ABC25884.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173622-2|ABC25879.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173621-2|ABC25874.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173620-2|ABC25869.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173619-2|ABC25864.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173618-2|ABC25859.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173617-2|ABC25854.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173616-2|ABC25849.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173615-2|ABC25844.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173614-2|ABC25839.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173613-2|ABC25834.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173612-2|ABC25829.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173611-2|ABC25824.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173610-2|ABC25819.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173609-2|ABC25814.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173608-2|ABC25809.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173607-2|ABC25804.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173606-2|ABC25799.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173605-2|ABC25794.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173604-2|ABC25789.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173603-2|ABC25784.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173602-2|ABC25779.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173601-2|ABC25774.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173600-2|ABC25769.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173599-2|ABC25764.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173598-2|ABC25759.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173597-2|ABC25755.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173596-2|ABC25750.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173595-2|ABC25745.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173594-2|ABC25740.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173593-2|ABC25735.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173592-2|ABC25730.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
DQ173589-1|ABB58724.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167726-1|AAO17629.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167725-1|AAO17628.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167724-1|AAO17627.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167723-1|AAO17626.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167722-1|AAO17625.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167721-1|AAO17624.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167720-1|AAO17623.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167719-1|AAO17622.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167718-1|AAO17621.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167717-1|AAO17620.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167716-1|AAO17619.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167715-1|AAO17618.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167714-1|AAO17617.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167713-1|AAO17616.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167712-1|AAO17615.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167711-1|AAO17614.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167710-1|AAO17613.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167709-1|AAO17612.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167708-1|AAO17611.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167707-1|AAO17610.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167706-1|AAO17609.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167705-1|AAO17608.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167704-1|AAO17607.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167703-1|AAO17606.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167702-1|AAO17605.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167701-1|AAO17604.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167700-1|AAO17603.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167699-1|AAO17602.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167698-1|AAO17601.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167697-1|AAO17600.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167696-1|AAO17599.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167695-1|AAO17598.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167694-1|AAO17597.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167693-1|AAO17596.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167692-1|AAO17595.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167691-1|AAO17594.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167690-1|AAO17593.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167689-1|AAO17592.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167688-1|AAO17591.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167687-1|AAO17590.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167686-1|AAO17589.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167685-1|AAO17588.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167684-1|AAO17587.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167683-1|AAO17586.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167682-1|AAO17585.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167681-1|AAO17584.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AY167680-1|AAO17583.1|  534|Homo sapiens L1 cell adhesion molecu...    91   1e-16
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe...    91   1e-16
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu...    91   1e-16
X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein.            90   2e-16
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.     90   2e-16
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe...    90   2e-16
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.        89   3e-16
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe...    89   3e-16
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe...    89   3e-16
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.     89   3e-16
BC031063-1|AAH31063.1|  602|Homo sapiens IGSF10 protein protein.       89   5e-16
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr...    89   5e-16
BC045734-1|AAH45734.1|  442|Homo sapiens IGSF10 protein protein.       88   6e-16
AK098838-1|BAC05429.1|  399|Homo sapiens protein ( Homo sapiens ...    88   6e-16
AK093069-1|BAC04042.1|  650|Homo sapiens protein ( Homo sapiens ...    88   6e-16
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c...    88   6e-16
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c...    88   6e-16
AB040929-1|BAA96020.1|  920|Homo sapiens KIAA1496 protein protein.     88   8e-16
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr...    87   1e-15
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr...    87   1e-15
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.        87   1e-15
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.        87   1e-15
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k...    87   1e-15
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k...    87   1e-15
AL049946-1|CAB43220.1|  584|Homo sapiens hypothetical protein pr...    87   1e-15
AK023854-1|BAB14704.1|  442|Homo sapiens .117).  protein.              87   1e-15
AF531872-1|AAN04866.1|  816|Homo sapiens transmembrane receptor ...    87   1e-15
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ...    87   1e-15
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase...    87   1e-15
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.             87   1e-15
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.       87   2e-15
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.               87   2e-15
BC048416-1|AAH48416.1|  353|Homo sapiens PTPRF protein protein.        86   3e-15
AL583862-12|CAI14897.1|  353|Homo sapiens protein tyrosine phosp...    86   3e-15
AB209350-1|BAD92587.1|  773|Homo sapiens PTK7 protein tyrosine k...    86   3e-15
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph...    85   5e-15
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph...    85   5e-15
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -...    85   6e-15
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole...    85   6e-15
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph...    85   6e-15
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp...    85   6e-15
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph...    85   6e-15
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.                  85   6e-15
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an...    85   8e-15
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an...    85   8e-15
BC012102-1|AAH12102.1|  347|Homo sapiens PTPRF protein protein.        85   8e-15
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno...    85   8e-15
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.              85   8e-15
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.              85   8e-15
AL583862-13|CAI14896.1|  347|Homo sapiens protein tyrosine phosp...    85   8e-15
AL583862-11|CAM12884.1|  262|Homo sapiens protein tyrosine phosp...    85   8e-15
AK074921-1|BAC11295.1|  697|Homo sapiens protein ( Homo sapiens ...    85   8e-15
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr...    85   8e-15
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein.                  84   1e-14
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein.       84   1e-14
X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein.            84   1e-14
BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein.       84   1e-14
BC098401-1|AAH98401.1|  771|Homo sapiens NRCAM protein protein.        84   1e-14
BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein ...    84   1e-14
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein.         84   1e-14
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.          84   1e-14
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.                84   1e-14
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ...    83   2e-14
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.        83   2e-14
BC036569-1|AAH36569.1|  627|Homo sapiens CNTN1 protein protein.        83   2e-14
AK090455-1|BAC03436.1|  931|Homo sapiens FLJ00376 protein protein.     83   2e-14
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an...    82   4e-14
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an...    82   4e-14
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.        82   4e-14
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an...    82   4e-14
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.     82   4e-14
DQ234351-1|ABB29980.1|  262|Homo sapiens protein tyrosine phosph...    82   6e-14
BC052946-1|AAH52946.1|  837|Homo sapiens neural cell adhesion mo...    82   6e-14
AK093583-1|BAC04201.1|  329|Homo sapiens protein ( Homo sapiens ...    82   6e-14
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.              81   1e-13
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p...    81   1e-13
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p...    81   1e-13
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat...    81   1e-13
BC036769-1|AAH36769.1|  504|Homo sapiens fibroblast growth facto...    80   2e-13
AY358303-1|AAQ88670.1|  504|Homo sapiens FGFRL1 protein.               80   2e-13
AK172829-1|BAD18794.1|  440|Homo sapiens protein ( Homo sapiens ...    80   2e-13
AJ277437-1|CAC14171.1|  504|Homo sapiens FGFR-like protein protein.    80   2e-13
AF312678-1|AAK15273.1|  497|Homo sapiens FGF homologous factor r...    80   2e-13
AF279689-1|AAK26742.1|  504|Homo sapiens fibroblast growth facto...    80   2e-13
AB037663-1|BAB21504.1|  992|Homo sapiens myosin light chain kina...    80   2e-13
X85337-1|CAA59685.1|  991|Homo sapiens myosin light chain kinase...    80   2e-13
U75330-1|AAB80803.1|  837|Homo sapiens neural cell adhesion prot...    80   2e-13
BC107797-1|AAI07798.1|  179|Homo sapiens TTN protein protein.          80   2e-13
BC043916-1|AAH43916.1|  767|Homo sapiens OBSCN protein protein.        80   2e-13
AY369208-1|AAQ73312.1|  956|Homo sapiens MAM domain-containing g...    80   2e-13
AY358125-1|AAQ88492.1|  937|Homo sapiens MAM-domain protein prot...    80   2e-13
AL353593-1|CAI19283.1|  709|Homo sapiens obscurin, cytoskeletal ...    80   2e-13
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ...    80   2e-13
AF040991-1|AAC39576.1|  285|Homo sapiens roundabout 2 protein.         80   2e-13
AK097578-1|BAC05109.1|  600|Homo sapiens protein ( Homo sapiens ...    79   4e-13
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph...    79   4e-13
AJ314904-1|CAC85751.1|  658|Homo sapiens obscurin protein.             79   5e-13
AJ314905-1|CAC85752.1| 2212|Homo sapiens obscurin protein.             78   7e-13
AB046776-1|BAB13382.1| 1596|Homo sapiens KIAA1556 protein protein.     78   7e-13
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat...    78   9e-13
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.        78   9e-13
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.        78   9e-13
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi...    78   9e-13
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph...    78   9e-13
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph...    78   9e-13
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph...    78   9e-13
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph...    78   9e-13
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi...    78   9e-13
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi...    78   9e-13
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph...    78   9e-13
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph...    78   9e-13
X90870-1|CAA62378.1|  458|Homo sapiens myosin-light-chain kinase...    77   1e-12
BC113458-1|AAI13459.1|  166|Homo sapiens MYLK protein protein.         77   1e-12
BC113456-1|AAI13457.1|  167|Homo sapiens MYLK protein protein.         77   1e-12
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.          77   1e-12
BC109098-1|AAI09099.1|  783|Homo sapiens MUSK protein protein.         77   1e-12
BC107783-1|AAI07784.1|  227|Homo sapiens MYLK protein protein.         77   1e-12
BC100763-1|AAI00764.2|  153|Homo sapiens myosin, light chain kin...    77   1e-12
BC100762-1|AAI00763.2|  154|Homo sapiens myosin, light chain kin...    77   1e-12
BC100761-1|AAI00762.2|  154|Homo sapiens myosin, light chain kin...    77   1e-12
BC064420-1|AAH64420.2|  153|Homo sapiens myosin, light chain kin...    77   1e-12
BC017811-1|AAH17811.1|  236|Homo sapiens MYLK protein protein.         77   1e-12
AL117666-1|CAB56036.1|  483|Homo sapiens hypothetical protein pr...    77   1e-12
AF096775-1|AAD54019.1|  154|Homo sapiens kinase-related protein ...    77   1e-12
AF096774-1|AAD54018.1|  153|Homo sapiens kinase-related protein ...    77   1e-12
AF096773-1|AAD54017.1|  154|Homo sapiens kinase-related protein ...    77   1e-12
AF096771-2|AAD51381.1|  153|Homo sapiens kinase related protein ...    77   1e-12
AF096771-1|AAD51380.1|  300|Homo sapiens smooth muscle/nonmuscle...    77   1e-12
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul...    77   1e-12
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.             77   2e-12
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.               77   2e-12
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.        76   3e-12
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch...    76   3e-12
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch...    76   3e-12
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch...    76   3e-12
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch...    76   3e-12
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch...    76   3e-12
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch...    76   3e-12
AL391822-2|CAI14657.1|  619|Homo sapiens neurofascin homolog (ch...    76   3e-12
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ...    76   3e-12
AB177861-1|BAD66839.1|  836|Homo sapiens KIAA0756 splice variant...    76   3e-12
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.     76   3e-12
AL353593-2|CAI19284.1|  416|Homo sapiens obscurin, cytoskeletal ...    76   4e-12
AF069604-1|AAD15924.1|  560|Homo sapiens myosin light chain kina...    76   4e-12
BC115397-1|AAI15398.1|  867|Homo sapiens IGSF22 protein protein.       75   5e-12
X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein.              75   6e-12
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ...    75   6e-12
M58051-1|AAA52450.1|  806|Homo sapiens fibroblast growth factor ...    75   6e-12
M34641-1|AAA35835.1|  820|Homo sapiens protein ( Human fibroblas...    75   6e-12
AY768549-1|AAU89726.1|  806|Homo sapiens fibroblast growth facto...    75   6e-12
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki...    75   6e-12
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki...    75   6e-12
AK095113-1|BAC04488.1|  903|Homo sapiens protein ( Homo sapiens ...    75   6e-12
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr...    75   6e-12
AB209441-1|BAD92678.1|  879|Homo sapiens fibroblast growth facto...    75   6e-12
X57120-1|CAA40402.1|  820|Homo sapiens Fibroblast Growth Factor ...    75   8e-12
M60485-1|AAA35840.1|  820|Homo sapiens fibroblast growth factor ...    75   8e-12
AJ314896-1|CAC85745.1|  163|Homo sapiens obscurin protein.             75   8e-12
AK128160-1|BAC87305.1|  632|Homo sapiens protein ( Homo sapiens ...    74   1e-11
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p...    74   1e-11
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr...    74   1e-11
AY211921-1|AAO65174.1|  294|Homo sapiens sarcoma antigen NY-SAR-...    73   2e-11
AK222718-1|BAD96438.1|  820|Homo sapiens fibroblast growth facto...    73   2e-11
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein.                  73   2e-11
X66945-1|CAA47375.1|  822|Homo sapiens fibroblast growth factor ...    73   3e-11
X57121-1|CAA40403.1|  822|Homo sapiens Fibroblast Growth Factor ...    73   3e-11
X52833-1|CAA37015.1|  822|Homo sapiens protein ( Human flg mRNA ...    73   3e-11
X51803-1|CAA36101.1|  822|Homo sapiens protein ( Human mRNA for ...    73   3e-11
M63888-1|AAA35959.1|  662|Homo sapiens heparin-binding growth fa...    73   3e-11
M63887-1|AAA35958.1|  822|Homo sapiens heparin-binding growth fa...    73   3e-11
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr...    73   3e-11
BC018128-1|AAH18128.1|  820|Homo sapiens fibroblast growth facto...    73   3e-11
BC015035-1|AAH15035.1|  820|Homo sapiens FGFR1 protein protein.        73   3e-11
AY585209-1|AAS79322.1|  822|Homo sapiens fibroblast growth facto...    73   3e-11
AK096458-1|BAC04796.1|  410|Homo sapiens protein ( Homo sapiens ...    73   3e-11
AB208919-1|BAD92156.1|  814|Homo sapiens fibroblast growth facto...    73   3e-11
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ...    72   4e-11
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro...    72   4e-11
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr...    72   4e-11
BC026119-1|AAH26119.1|  697|Homo sapiens contactin 4 protein.          72   4e-11
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr...    72   4e-11
X58776-1|CAB37831.1|  824|Homo sapiens cell adhesion molecule L1...    72   6e-11
X56191-1|CAA39654.1|  769|Homo sapiens fibroblast growth factor ...    72   6e-11
X16841-1|CAA34739.1|  761|Homo sapiens protein ( Human mRNA for ...    72   6e-11
U11814-1|AAA68514.1|  366|Homo sapiens soluble keratinocyte grow...    72   6e-11
S71824-1|AAB31836.1|  848|Homo sapiens N-CAM protein.                  72   6e-11
M97193-1|AAA52449.1|  822|Homo sapiens fibroblast growth factor ...    72   6e-11
M80634-1|AAA36147.1|  822|Homo sapiens keratinocyte growth facto...    72   6e-11
AK130921-1|BAC85460.1|  572|Homo sapiens protein ( Homo sapiens ...    72   6e-11
AF487553-1|AAM74056.1|  822|Homo sapiens fibroblast growth facto...    72   6e-11
AF360695-1|AAK94206.1|  820|Homo sapiens keratinocyte growth fac...    72   6e-11
AB209443-1|BAD92680.1|  807|Homo sapiens Neural cell adhesion mo...    72   6e-11
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari...    72   6e-11
AB030078-1|BAA89301.1|  768|Homo sapiens K-sam-IIO3 protein.           72   6e-11
AB030077-1|BAA89300.1|  817|Homo sapiens K-sam-IIO2 protein.           72   6e-11
AB030076-1|BAA89299.1|  771|Homo sapiens K-sam-IIO1 protein.           72   6e-11
AB030075-1|BAA89298.1|  830|Homo sapiens K-sam-IIH3 protein.           72   6e-11
AB030074-1|BAA89297.1|  819|Homo sapiens K-sam-IIH2 protein.           72   6e-11
AB030073-1|BAA89296.1|  819|Homo sapiens K-sam-IIH1 protein.           72   6e-11
AF538973-1|AAN16368.1|  437|Homo sapiens nectin-like protein 3 p...    71   1e-10
BC109099-1|AAI09100.1|  773|Homo sapiens MUSK protein protein.         71   1e-10
AL513328-2|CAI17350.1|  867|Homo sapiens muscle, skeletal, recep...    71   1e-10
AL513328-1|CAI17349.1|  875|Homo sapiens muscle, skeletal, recep...    71   1e-10
AL157881-3|CAH69978.1|  867|Homo sapiens muscle, skeletal, recep...    71   1e-10
AL157881-2|CAH69977.1|  875|Homo sapiens muscle, skeletal, recep...    71   1e-10
AF487554-2|AAM22078.1|  769|Homo sapiens fibroblast growth facto...    71   1e-10
AF006464-1|AAB63044.1|  869|Homo sapiens muscle specific tyrosin...    71   1e-10
U27266-1|AAB86737.1|  477|Homo sapiens myosin binding protein H ...    70   2e-10
X57122-1|CAA40404.1|  731|Homo sapiens Fibroblast Growth Factor ...    70   2e-10
X57119-1|CAA40401.1|  733|Homo sapiens Fibroblast Growth Factor ...    70   2e-10
M37722-1|AAA75007.1|  731|Homo sapiens basic fibroblast growth f...    70   2e-10
M34185-1|AAA35836.1|  733|Homo sapiens protein ( Human fibroblas...    70   2e-10
L34774-1|AAA36387.1|  345|Homo sapiens opioid-binding cell adhes...    70   2e-10
BX537377-1|CAD97619.1|  338|Homo sapiens hypothetical protein pr...    70   2e-10
BC126251-1|AAI26252.1|  345|Homo sapiens opioid binding protein/...    70   2e-10
BC117254-1|AAI17255.1|  345|Homo sapiens opioid binding protein/...    70   2e-10
BC091494-1|AAH91494.1|  731|Homo sapiens fibroblast growth facto...    70   2e-10
BC074773-1|AAH74773.1|  345|Homo sapiens opioid binding protein/...    70   2e-10
BC044226-1|AAH44226.1|  477|Homo sapiens myosin binding protein ...    70   2e-10
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo...    70   2e-10
X69089-1|CAA48832.1| 1465|Homo sapiens 165kD protein protein.          69   4e-10
BC112138-1|AAI12139.1|  435|Homo sapiens CADM2 protein protein.        69   4e-10
BC112136-1|AAI12137.1|  435|Homo sapiens CADM2 protein protein.        69   4e-10
BC105999-1|AAI06000.1|  404|Homo sapiens CADM2 protein protein.        69   4e-10
BC047244-1|AAH47244.1|  858|Homo sapiens neural cell adhesion mo...    69   4e-10
AK131073-1|BAC85123.1|  659|Homo sapiens FLJ00259 protein protein.     69   4e-10
AK027343-1|BAB55048.1|  507|Homo sapiens .117).  protein.              69   4e-10
AF487554-1|AAM22079.1|  771|Homo sapiens fibroblast growth facto...    69   4e-10
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr...    69   4e-10
X57205-1|CAA40490.1|  802|Homo sapiens fibroblast growth factor ...    69   6e-10
U63041-1|AAB04558.1|  848|Homo sapiens neural cell adhesion mole...    69   6e-10
L03840-1|AAB59389.1|  802|Homo sapiens fibroblast growth factor ...    69   6e-10
BC052969-1|AAH52969.1| 1465|Homo sapiens myomesin (M-protein) 2,...    69   6e-10
BC011847-1|AAH11847.1|  802|Homo sapiens fibroblast growth facto...    69   6e-10
Y13901-1|CAA74200.1|  802|Homo sapiens fibroblast growth factor ...    68   7e-10
M34186-1|AAA35837.1|  731|Homo sapiens protein ( Human fibroblas...    68   7e-10
EF571596-1|ABQ01235.1|  802|Homo sapiens fibroblast growth facto...    68   7e-10
AF487555-1|AAM13666.1|  802|Homo sapiens fibroblast growth facto...    68   7e-10
AF202063-1|AAF27432.1|  762|Homo sapiens fibroblast growth facto...    68   7e-10
M35718-1|AAA36152.1|  682|Homo sapiens protein ( Human heparin-b...    67   1e-09
Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C ...    67   2e-09
U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding pr...    67   2e-09
BC008124-1|AAH08124.2|  294|Homo sapiens NFASC protein protein.        67   2e-09
AF245114-1|AAF63380.1|  694|Homo sapiens fibroblast growth facto...    67   2e-09
X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding pr...    66   2e-09
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein.         66   2e-09
AY358330-1|AAQ88696.1|  477|Homo sapiens papilin protein.              66   2e-09
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo...    66   2e-09
AC005338-1|AAC27825.1|  475|Homo sapiens PTPsigma, partial CDS p...    66   3e-09
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr...    66   4e-09
AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein ...    66   4e-09
AL049553-2|CAI20461.1|  957|Homo sapiens MAM domain containing g...    66   4e-09
AF478693-1|AAM77220.1|  955|Homo sapiens glycosyl-phosphatidyl-i...    66   4e-09
BC111395-1|AAI11396.1|  554|Homo sapiens NEXN protein protein.         65   7e-09
BC029496-1|AAH29496.1|  128|Homo sapiens PTPRS protein protein.        65   7e-09
BC029119-1|AAH29119.1|  364|Homo sapiens NCAM1 protein protein.        65   7e-09
AK057954-1|BAB71622.1|  505|Homo sapiens protein ( Homo sapiens ...    65   7e-09
AF114264-1|AAD29607.1|  448|Homo sapiens unknown protein.              65   7e-09
AC005790-1|AAC62832.1|  126|Homo sapiens PTP sigma [AA 1- 126] p...    65   7e-09
BC074742-1|AAH74742.1|  344|Homo sapiens opioid binding protein/...    64   9e-09
DQ464902-1|ABE97925.1|  675|Homo sapiens nexilin protein.              64   1e-08
BX640951-1|CAE45975.1|  370|Homo sapiens hypothetical protein pr...    64   1e-08
BC114445-1|AAI14446.1|  567|Homo sapiens NEXN protein protein.         64   1e-08
BC114444-1|AAI14445.1|  567|Homo sapiens NEXN protein protein.         64   1e-08
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein.                 64   1e-08
BC013955-1|AAH13955.2|  365|Homo sapiens FGFRL1 protein protein.       63   2e-08
X64699-1|CAA45940.1|  531|Homo sapiens titin protein.                  63   3e-08
M64347-1|AAA58470.1|  731|Homo sapiens fgflr protein.                  63   3e-08
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein.        62   5e-08
BC014276-1|AAH14276.2|  417|Homo sapiens LRIG1 protein protein.        62   5e-08
AJ314903-1|CAC85750.1|  542|Homo sapiens obscurin protein.             62   5e-08
U57099-1|AAC50599.1|  113|Homo sapiens APEG-1 protein protein.         62   6e-08
CR542201-1|CAG46998.1|  113|Homo sapiens APEG1 protein.                62   6e-08
BC006346-1|AAH06346.1|  113|Homo sapiens SPEG protein protein.         62   6e-08
AK128689-1|BAC87572.1|  175|Homo sapiens protein ( Homo sapiens ...    62   6e-08
AK126500-1|BAC86568.1|  170|Homo sapiens protein ( Homo sapiens ...    62   6e-08
AC053503-3|AAY15052.1|  113|Homo sapiens unknown protein.              62   6e-08
EF043567-1|ABK34282.1|  355|Homo sapiens neurotrimin variant 3 p...    61   8e-08
BC050716-1|AAH50716.1|  316|Homo sapiens HNT protein protein.          61   8e-08
AY358331-1|AAQ88697.1|  344|Homo sapiens HNT protein.                  61   8e-08
AJ314898-1|CAC85746.1|  646|Homo sapiens obscurin protein.             61   8e-08
AF126426-1|AAF37591.1|  344|Homo sapiens neurotrimin protein.          61   8e-08

>AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein.
          Length = 5604

 Score =  296 bits (726), Expect = 1e-78
 Identities = 269/1028 (26%), Positives = 456/1028 (44%), Gaps = 98/1028 (9%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY---RTVYDMGF 3886
            P F+ ++K+  ++E  G R E +V    +P   I W +N  ++   H+Y   R     G 
Sbjct: 1556 PMFVEKLKNVNIKE--GSRLEMKVRATGNPNPDIVWLKNSDIIVP-HKYPKIRIEGTKGE 1612

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK---KLPDIILQNQVPRGMKRSE-- 3941
             +L I    ++DS  Y   A+N  G D T+  ++ +     P+   +  +PRG  R++  
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 3942 ALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVG 4001
            A  ++E    +Y  E +  E DLYD +K+Q P F  ++ S   L       FEC+L P+G
Sbjct: 1673 AAPELEPLHLRYGQEQW-EEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPIG 1730

Query: 4002 DPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
            DP M VEW  +GKPL   NR   I +FGY ++++G  Y  DSG   CRATN YG D T A
Sbjct: 1731 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1790

Query: 4062 VIKTTGKPGIVYDSQLPKHMKSIEKIREMEA-SWQVTPEQVVEESKARCPPVFVSLPDAV 4120
             +    +  +V +SQLP+  K +++I E+E  + +     V  + K +  P  V  P+ V
Sbjct: 1791 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1850

Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGKI 4180
             V EGE ARF CRVTG+P+P+V W LNG  I    R+++ YDG+++ DI   + YDTG++
Sbjct: 1851 RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEV 1910

Query: 4181 EVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYD-ETTQYQRTETELEK------ 4233
            +V              L++  R +D+R VL+ AP P  +    +  + + E++K      
Sbjct: 1911 KVTAENPEGVIEHKVKLEIQQR-EDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVD 1969

Query: 4234 TFEERQV--LQRQGVIDHRP------ELKPKVIKEPETEWQQSV------KRKKNEEYYN 4279
            T E ++V  L+R   I H        EL+ K  +  E  + +++       RKK+E Y  
Sbjct: 1970 TTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEE 2029

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQT---EEVTEQR 4336
             L++ ++E +     L E   +      K+T  T      +    +++     E +  Q 
Sbjct: 2030 LLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIE-LSPSMEAPKIFERIQSQT 2088

Query: 4337 VQKKVTQKPRI-----PDPSESTVHGKEVHVAKQKQTQKEVVGDKE---ITRKITSTETT 4388
            V +      R+     PDP E   +   V + +  +       D     + R +T+ ++ 
Sbjct: 2089 VGQGSDAHFRVRVVGKPDP-ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSA 2147

Query: 4389 EIEHKAQTQERVVEGP----VKPSKPPIFTKKMQPCRVFEHE-QARFEVEFDGEPLPLIK 4443
             I  KA              V+  +   FT+++Q     E +  A FE E   EP   +K
Sbjct: 2148 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECE-TSEPFVKVK 2206

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            WY++   +     +++H+      L I  +   D+  ++ V        K +A L+VE  
Sbjct: 2207 WYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE-DENVKTTAKLIVE-- 2263

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                 G +V   F    Q++ V       L+  +   + I+  W  N  +++ + +  I 
Sbjct: 2264 -----GAVV--EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTIT 2315

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623
               G   L + +   +D G+Y  V      +  C           K K KP+      P 
Sbjct: 2316 SRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTC-----------KLKMKPR------PI 2356

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
             I++ L D+ V EG  ++   K+  + +  V W K  + ++PS    +      + L I 
Sbjct: 2357 AILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIE 2415

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
            +   ED G+Y       A  ++ + ++ V   D       +TPL+D+ V EG  A  + +
Sbjct: 2416 DMTKEDAGNYSFTI--PALGLSTSGRVSVYSVD------VITPLKDVNVIEGTKAVLECK 2467

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            ++     +++W      I      Q I +G    L+I  T+  D G +        G+VE
Sbjct: 2468 VSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY----KLIVGRVE 2523

Query: 4804 TSAKLVVK 4811
            T+  L V+
Sbjct: 2524 TNCNLSVE 2531



 Score =  257 bits (629), Expect = 8e-67
 Identities = 163/511 (31%), Positives = 249/511 (48%), Gaps = 14/511 (2%)

Query: 377  RETEERIEIS-EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            R  EE  E   E+   P FV         EG+  RFD +V GRP PE  WF + +QI +D
Sbjct: 1441 RRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVND 1500

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
            Y HK+++ E G  +L+I   T SDSG  T VA+N++G ++    L V   E  V P FVE
Sbjct: 1501 YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560

Query: 496  RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN--PELRIHTDGGASTLDIPRA 553
            +   +N++EG  + +  RA G P P I W K+   I+P+  P++RI    G + L I   
Sbjct: 1561 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDST 1620

Query: 554  KASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXX 613
             + D+AWY  TA N AG   TR ++           +++L +PR T              
Sbjct: 1621 VSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPL 1680

Query: 614  YLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            +LR+ +         ++++    P F   L S+     G  HFE R+ P+GDPTM +EWL
Sbjct: 1681 HLRYGQEQWEEGDLYDKEK-QQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWL 1739

Query: 674  KNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             +G+ +EA++R   I  FGY SLD      +DSG  TCRA +  G   T A L V    +
Sbjct: 1740 HDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKS 1799

Query: 734  IERTSQHPETLQYIQQLEDYSKYQHQESI-----EEQTSQRPQFIRPLQDLGELQEGRNA 788
            +   SQ PE  + +Q++E+  +  H+ ++     +++  Q+P  +   + +  L EG  A
Sbjct: 1800 LVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVL-EGETA 1858

Query: 789  HFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAV 848
             F  ++T    P  +V WY +G+ I  S R    ++ G   L+I+  ++ D G   V A 
Sbjct: 1859 RFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAE 1915

Query: 849  NKLGEAISTASIRVAARSTVTADL-GIPEQR 878
            N  G       + +  R    + L   PE R
Sbjct: 1916 NPEGVIEHKVKLEIQQREDFRSVLRRAPEPR 1946



 Score =  188 bits (457), Expect = 6e-46
 Identities = 221/822 (26%), Positives = 347/822 (42%), Gaps = 106/822 (12%)

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTN-KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
            R  +  E +++   KP F+  LK  + K +EGQ+A F+ +V  +  +  T  W+ +G+QI
Sbjct: 1442 RLEETDESQLERLYKPVFV--LKPVSFKCLEGQTARFDLKVVGRP-MPETF-WFHDGQQI 1497

Query: 1087 TS--ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTS 1144
             +   +++    D G  +L I      DSG +TVVA+N AG + +S  +TVE        
Sbjct: 1498 VNDYTHKVVIKED-GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA------- 1549

Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPM 1204
                        +E    V+PM+    + K K V ++         EG  +  E ++   
Sbjct: 1550 ------------VEHQ--VKPMF----VEKLKNVNIK---------EGSRL--EMKVRAT 1580

Query: 1205 GDPTMRVEWFHNGRSVTVGS--RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAH 1262
            G+P   + W  N   +      + +     G  AL I    S D+  YT  A+N  G   
Sbjct: 1581 GNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDT 1640

Query: 1263 TSAIVRV--------IERSDIV---TDTQNEQAIEQIQLLEDAARRTKQVREDI---TVM 1308
            T   V V         ER  I+   T    E A  +++ L     + +    D+      
Sbjct: 1641 TRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQ 1700

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P F + L ++        H ECRL P+GD TM VEW  +GKP++  +R R   EF Y 
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1760

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            +LD    Y  DSG+ TC+ATN+ G   TS  L V  +K L+ ESQ P G + +Q +E+  
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELE 1820

Query: 1429 RYKKTDII-----DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN 1483
            R      +     D+    KP  V  P+ +  V+EG+   F C++        KV W+ N
Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLN 1877

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            GQ +    RFR  +D G   LDI+D  + D+G     A N  G  E   +L  +   D  
Sbjct: 1878 GQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF- 1935

Query: 1544 RSTQNEA--GLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKN-VEIKEGQRAHFERR 1600
            RS    A     +  V E          VD      P+ TT  K  V++K  +R   E+ 
Sbjct: 1936 RSVLRRAPEPRPEFHVHEPGKLQFEVQKVDR-----PVDTTETKEVVKLKRAERITHEK- 1989

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNF-GFVALDIMSCLPEDSGTYTCRAINALG 1659
             +P     L+ ++           R TE   +    A+++ S   ++S     R      
Sbjct: 1990 -VPEESEELRSKF----------KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-- 2036

Query: 1660 EAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKD 1719
                    ++H  K   L  + + AL    ++     ++    +     +AP     ++ 
Sbjct: 2037 -------ELLHWTKE--LTEEEKKALAEEGKI-TIPTFKPDKIELSPSMEAPKIFERIQS 2086

Query: 1720 IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPE 1778
              V +   AHF  R+  VG P    EW +NGV IE S+R+        V  L ++ V  E
Sbjct: 2087 QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2144

Query: 1779 DSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
            DS +   +AIN  GE  + + L VQ+K  +    + +  + K
Sbjct: 2145 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2186



 Score =  187 bits (455), Expect = 1e-45
 Identities = 178/649 (27%), Positives = 284/649 (43%), Gaps = 60/649 (9%)

Query: 3293 KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT-FHDFGIVILDILYCYEEN 3351
            +++EG    F  ++     P  K+ W+ +GK++ HG RY+  F   G   L I     E+
Sbjct: 1301 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358

Query: 3352 SGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTS 3411
             G Y   A+N       K N  C+ K  L ++   P G       + TLE   V R  + 
Sbjct: 1359 EGIYTAFASN------IKGNAICSGK--LYVEPAAPLGAP---TYIPTLEP--VSRIRSL 1405

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTP------TDDPNL----KVEWYWNGK 3461
                  ++P+   P + +   R        AR++P      TD+  L    K  +     
Sbjct: 1406 SPRSVSRSPIRMSP-ARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV 1464

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            S K         D   V   +  T+    G+ +    N+Y   V    +K  G +++I+ 
Sbjct: 1465 SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV---NDYTHKVV---IKEDGTQSLIIV 1518

Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEA-ESGNPPEFTTTPSDLILSENSSAHFECR 3580
               P              G S     LT EA E    P F     ++ + E S    E +
Sbjct: 1519 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGS--RLEMK 1576

Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGS--RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
            +    + +  + W  N   ++     +++     G   L+I     +D+  YT  A N+ 
Sbjct: 1577 VRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1636

Query: 3639 GEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE----ETLHKR------EEITIE 3688
            G  T  CK+ V+  +    EP+       GT   +++     E LH R      EE  + 
Sbjct: 1637 GRDTTRCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1695

Query: 3689 D-EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            D EK   P F  ++  ++ +   GP HF+CR+ P+GDPTM ++W H+G+P    +R+  +
Sbjct: 1696 DKEKQQKPFFKKKLT-SLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMI 1754

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSG-E 3806
            N+FG+ +LD    Y+RD+G  TCRATNK+G+  T+A +    ++ +V ESQLP+G  G +
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQ 1814

Query: 3807 KIKELER----GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            +I+ELER    G ++    ++      P  +   +   V E E  RF CRV     PK  
Sbjct: 1815 RIEELERMAHEGALTGVTTDQK-EKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPK-- 1871

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            + WY NG+L+    R+R  YD G   LDI+   + D+GE    A N  G
Sbjct: 1872 VNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1919



 Score =  176 bits (428), Expect = 2e-42
 Identities = 157/534 (29%), Positives = 234/534 (43%), Gaps = 64/534 (11%)

Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488
            R ++TD        KP FV +P S +  +EGQ   F+ K+  V     +  WF +GQ + 
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFK-CLEGQTARFDLKV--VGRPMPETFWFHDGQQIV 1498

Query: 1489 IGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
              +  +  I + G  +L I+     DSG +T  A                         Q
Sbjct: 1499 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVA-------------------------Q 1533

Query: 1548 NEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEGQRAHFERRLIPVSD 1606
            N AG   I V+           V+ V  Q  P+    LKNV IKEG R   E ++    +
Sbjct: 1534 NRAGRSSISVILT---------VEAVEHQVKPMFVEKLKNVNIKEGSR--LEMKVRATGN 1582

Query: 1607 ATLKVEWYHNNKPLKSGS--RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                + W  N+  +      +       G  AL I S + +DS  YT  AIN  G   T 
Sbjct: 1583 PNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1642

Query: 1665 GIAIVH--------SKKSIYLESQH---EGALPRLNQLE---DTSKYQRHSAQDEVITQA 1710
                V          +K I     +   E A P L  L       +++     D+   Q 
Sbjct: 1643 CKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQK 1702

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +  +R+     AHFE RL P+GDP + VEWL +G P+EA+NRL  +++FGY +L
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1762

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
            +       DSG  TCRA N+ G   TS+TL V+ + SL  ESQ     + +Q++E+  R 
Sbjct: 1763 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1822

Query: 1831 QRREDVE-VAVNQAPR---FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                 +  V  +Q  +    I     P ++ EG++A + CR+  YP P  +V WY NG++
Sbjct: 1823 AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQL 1880

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++   R+R   D G   LDI+     D+GE    A N  G     ++L +Q +E
Sbjct: 1881 IRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1933



 Score =  165 bits (402), Expect = 3e-39
 Identities = 136/477 (28%), Positives = 216/477 (45%), Gaps = 33/477 (6%)

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            EGQ A ++  ++  G       WF++G+ I  + +H++  +   G   L I+    +DSG
Sbjct: 1470 EGQTARFDLKVV--GRPMPETFWFHDGQQIVNDYTHKV-VIKEDGTQSLIIVPATPSDSG 1526

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             ++  A N+ G++ ISV L         KP F   ++N+  +K+G  +  E  V    +P
Sbjct: 1527 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNV-NIKEG--SRLEMKVRATGNP 1583

Query: 3180 DMKIEWYHNGQ---PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
            +  I W  N     P ++  +I+     G   L I  T + DS  Y   A NK G D TR
Sbjct: 1584 NPDIVWLKNSDIIVPHKY-PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1642

Query: 3237 ATINC---YGKGGVYLESLQPDSLAKIRELES-------LQGAQQQTPSTPSAEPPK--- 3283
              +N    + +     + + P    + +E+ +       L+  Q+Q       +  K   
Sbjct: 1643 CKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQK 1702

Query: 3284 -FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
             F  +     +L     AHFE RL P+ DP + VEW ++GK L   +R R  ++FG   L
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1762

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG--GLEKLQTL 3400
            D    Y  +SG   C ATNK G D T A L    +++L+ +SQLP G +G   +E+L+ +
Sbjct: 1763 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1822

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
                     T+ ++EK K  +   P      + EGE A F  R+T    P  KV WY NG
Sbjct: 1823 AHEGALTGVTTDQKEKQKPDIVLYP--EPVRVLEGETARFRCRVTGYPQP--KVNWYLNG 1878

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
            + ++   RFR   D G   L+I      D+GE    A N  G       +++Q + +
Sbjct: 1879 QLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1934



 Score =  162 bits (393), Expect = 3e-38
 Identities = 166/643 (25%), Positives = 270/643 (41%), Gaps = 50/643 (7%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSY--VS 2832
            +F+  L N+  KEG  +  E  V  + +P   I W  N+  +      K   + +    +
Sbjct: 1557 MFVEKLKNVNIKEGSRL--EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1614

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLE------- 2885
            L I  T  +DS  YT  A N  G  TT    RC  +  + F    P+ K  +        
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTT----RCKVNVEVEFAEPEPERKLIIPRGTYRAK 1670

Query: 2886 --AVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKN 2939
              A  + E   L  G+        Y K +   P   +     +L      H E ++ P  
Sbjct: 1671 EIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIG 1730

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            DP + +EW  +GK LE  +R ++ ++FG+ +LD    Y RDSGI TC+A NK G   TS+
Sbjct: 1731 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1790

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKE--PGQQPDDDTGRPPEFTTVFKDI 3057
            T+    + +L+E +Q P+G +GL++I+ LE    +    G   D    + P+   ++ + 
Sbjct: 1791 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEP 1849

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V + EG+ A +   +  TG     + W+ NG+ I  S R R  Y  G+  L+I+  K+ D
Sbjct: 1850 VRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYD 1906

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKS-------KGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            +G     A N  G  E  VKLE   +        +  +PR   H+     L+      FE
Sbjct: 1907 TGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQ------FE 1960

Query: 3171 CTVV--PVDDPDMK-IEWYHNGQPMRHSTRIKTVSDFGFVV---LDIAYTQNHDSGEYVC 3224
               V  PVD  + K +      + + H    +   +         +  Y +   + E   
Sbjct: 1961 VQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKS 2020

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            R  ++  E+  R T +        L   +  +LA+  ++        +   +PS E PK 
Sbjct: 2021 RKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKI 2080

Query: 3285 ITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR-YRTFHDFGIVILD 3343
              +IQ  T + +G  AHF  R+V   DP+   EW+ NG K+    R Y  + +  +  L 
Sbjct: 2081 FERIQSQT-VGQGSDAHFRVRVVGKPDPE--CEWYKNGVKIERSDRIYWYWPEDNVCELV 2137

Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQL 3386
            I     E+S      A N  G  S+ A L   +K+ +    +L
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQEL 2180



 Score =  157 bits (382), Expect = 7e-37
 Identities = 142/530 (26%), Positives = 241/530 (45%), Gaps = 41/530 (7%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS-NDFGFAALDILTVYGED 1913
            K  EGQ+A ++ ++   P P     W+ +G+ + + + ++    + G  +L I+     D
Sbjct: 1467 KCLEGQTARFDLKVVGRPMPE--TFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSD 1524

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSF 1973
            SGE+T  A N  G++  S+ L V++ E  ++    E  L+ +  +++ SR +  V+    
Sbjct: 1525 SGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEK-LKNVN-IKEGSRLEMKVRATG- 1581

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
                P     +KN+++           + P   P +R+E    G    +     +     
Sbjct: 1582 -NPNPDI-VWLKNSDI-----------IVPHKYPKIRIEG-TKGEAALKIDSTVSQDSAW 1627

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLY----LDTLDEQRLKKIQ 2089
            Y A  I  A  + T    CK    V  A      K+    G Y    +   + + L    
Sbjct: 1628 YTATAINKAGRDTT---RCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1684

Query: 2090 ELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
              E++E     ++E+  Q+P F   LTSL  LK    AHFECR+ PI DP + ++W H+G
Sbjct: 1685 GQEQWEEGDLYDKEKQ-QKPFFKKKLTSL-RLKRFGPAHFECRLTPIGDPTMVVEWLHDG 1742

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
            + + A +R R  ++FGY +LD    Y+ DSG   C+ATNK G    + TL V   ++++ 
Sbjct: 1743 KPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVE 1802

Query: 2210 DTQHP---NGLEKIRQLEAQGHS---TRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFE 2263
            ++Q P    GL++I +LE   H    T +  ++ +   P  V        V EG+TA F 
Sbjct: 1803 ESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVL-YPEPVRVLEGETARFR 1861

Query: 2264 CQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINAL 2323
            C+V     P  ++ +Y NG+ ++ + RF + +D G   LDI  C   D GE  V A N  
Sbjct: 1862 CRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPE 1918

Query: 2324 GHCTSAISMTVTAKGSIISESQR-PEGLEKIRELESAE-PFKRPEIPEPV 2371
            G     + + +  +    S  +R PE   +    E  +  F+  ++  PV
Sbjct: 1919 GVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPV 1968



 Score =  153 bits (370), Expect = 2e-35
 Identities = 167/695 (24%), Positives = 296/695 (42%), Gaps = 69/695 (9%)

Query: 1939 KESIIRDSQH---ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPV 1995
            +E +I++ ++   ++ LE++  LE+D   K AV        +  F   IKN  + EG  V
Sbjct: 1251 EERLIKEIEYRIIKTTLEEL--LEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGV 1308

Query: 1996 HLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCKA 2054
                 ++    P  ++ WY +G+ ++ G R++  +   G  +L I     ED G Y   A
Sbjct: 1309 TFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA 1366

Query: 2055 TNAVGEAVTTSSVKVDAKSGL----YLDTLDEQRLKKIQELEKYERPK-PIEEEQPGQRP 2109
            +N  G A+ +  + V+  + L    Y+ TL+   + +I+ L      + PI        P
Sbjct: 1367 SNIKGNAICSGKLYVEPAAPLGAPTYIPTLEP--VSRIRSLSPRSVSRSPIRMSPARMSP 1424

Query: 2110 VFLT-ALTSLENLKEGDRAHF--ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
              ++ A  S   +  G R     E ++E +  P   +       K   G   R   D   
Sbjct: 1425 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV--SFKCLEGQTAR--FDLKV 1480

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLE 2224
            V   +  T+    G  +      + +  +   +K  G +++I+    P+  G   +    
Sbjct: 1481 VGRPMPETFWFHDGQQI------VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQN 1534

Query: 2225 AQGHST-----RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
              G S+      +E  E ++ P  FV +L+   ++ EG  +  E +V    +PN  I + 
Sbjct: 1535 RAGRSSISVILTVEAVEHQVKP-MFVEKLKNV-NIKEG--SRLEMKVRATGNPNPDIVWL 1590

Query: 2280 HNGKAL--QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             N   +      +  I    G  +L I   V +D+  Y+  AIN  G  T+   + V  +
Sbjct: 1591 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650

Query: 2338 GSIISESQR---PEGLEKIRELESAE-----------PFKRPEIPEPVTRQRPVFTQPLQ 2383
             +     ++   P G  + +E+ + E            ++  ++ +   +Q+P F + L 
Sbjct: 1651 FAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLT 1710

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++  ++    AHF+CRL P+GDPT+ VEW  + K +E ++R+   ++FGY S+       
Sbjct: 1711 SL-RLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYS 1769

Query: 2444 EDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE--- 2500
             D G+  CRA+N  G               +  E+Q PEG K +Q++E+  ER + E   
Sbjct: 1770 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEE-LERMAHEGAL 1828

Query: 2501 -----PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555
                   +E +KP    +   P  + EG+ A +  RV   G P  +  WY+NG  ++   
Sbjct: 1829 TGVTTDQKEKQKPDIV-LYPEPVRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSK 1885

Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            RFR  +D G   LDI    + D G     A N  G
Sbjct: 1886 RFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1919



 Score =  153 bits (370), Expect = 2e-35
 Identities = 172/672 (25%), Positives = 280/672 (41%), Gaps = 59/672 (8%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASS-- 817
            E++E Q   +P F+  L+++  ++EG  +  E ++    +P   + W K+   I      
Sbjct: 1548 EAVEHQV--KPMFVEKLKNVN-IKEG--SRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP 1602

Query: 818  RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA---ARSTVTADLGI 874
            +I      G  +L I    ++D+  YT  A+NK G   +   + V    A       L I
Sbjct: 1603 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1662

Query: 875  PE---QRRYI---EKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
            P    + + I   E                     E  QKP FK  +   + +K  G AH
Sbjct: 1663 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAH 1721

Query: 929  FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
            FE RL PIGD T+ VEWL DG+P+EA++R+     FGY +L        D+G  TCRA N
Sbjct: 1722 FECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1781

Query: 989  AIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKR-----TEEEVKITQKP 1043
              G   TSA L +  +K ++ ESQ P G + +Q +E+  R +          + K  QKP
Sbjct: 1782 KYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKP 1841

Query: 1044 RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVAL 1103
              +       +++EG++A F  RV         V WY NG+ I  + R +  +D G   L
Sbjct: 1842 DIV-LYPEPVRVLEGETARFRCRVTGYPQ--PKVNWYLNGQLIRKSKRFRVRYD-GIHYL 1897

Query: 1104 DIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFV 1163
            DI   ++ D+G   V A N  G  +    + ++ R   D  S+ R   E           
Sbjct: 1898 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE--DFRSVLRRAPEP---------- 1945

Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223
             P + + E  K +   VQ +  P   +E K +    R E +    +  E      S  + 
Sbjct: 1946 RPEFHVHEPGKLQ-FEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE------SEELR 1998

Query: 1224 SRFKTYYDFGFV-ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
            S+FK   + G+  A+  +   S    E     +             ++  +  +T+ + +
Sbjct: 1999 SKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-------ELLHWTKELTEEEKK 2051

Query: 1283 QAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTM 1342
               E+ ++     +  K   E    M+AP+    + +    +G++ H   R++ VG    
Sbjct: 2052 ALAEEGKITIPTFKPDK--IELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRVVGKPDP 2107

Query: 1343 RVEWFCNGKPIKTGHRFRPAYEFDYVA-LDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
              EW+ NG  I+   R    +  D V  L +  V  EDS     +A N  GE  +S A  
Sbjct: 2108 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE-TSSHAFL 2166

Query: 1402 VIAKKDLILESQ 1413
            ++  K LI  +Q
Sbjct: 2167 LVQAKQLITFTQ 2178



 Score =  147 bits (355), Expect = 1e-33
 Identities = 112/386 (29%), Positives = 180/386 (46%), Gaps = 22/386 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGH-RYRTFHDFGI 3339
            P F+ ++++V  + EG     + R     +PD  + W  N   + PH + + R     G 
Sbjct: 1556 PMFVEKLKNVN-IKEGSRLEMKVRATGNPNPD--IVWLKNSDIIVPHKYPKIRIEGTKGE 1612

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDST--KANLKCTSKE-----NLILDSQLPRGMEG 3392
              L I     ++S  Y   A NK GRD+T  K N++    E      LI+     R  E 
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 3393 GLEKLQTLEDSMVRRK---DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
               +L+ L     + +       ++EK + P F   L+++   R G  AHFE RLTP  D
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGP-AHFECRLTPIGD 1731

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P + VEW  +GK L+A +R R   +FG+  L+    Y  DSG   CRA N YG   T+A+
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791

Query: 3510 MKVQGKRNIILESQLPKGMEGTIDKIAALE--GYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
            + V+ +++++ ESQLP+G +G + +I  LE   + G +  +T + +    P+    P  +
Sbjct: 1792 LIVKDEKSLVEESQLPEGRKG-LQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1850

Query: 3568 ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDA 3627
             + E  +A F CR+        +V W+ NG+ +    R +   D G   L+I      D 
Sbjct: 1851 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1907

Query: 3628 GLYTCKATNRHGEATVSCKLQVKGRQ 3653
            G     A N  G      KL+++ R+
Sbjct: 1908 GEVKVTAENPEGVIEHKVKLEIQQRE 1933



 Score =  146 bits (354), Expect = 2e-33
 Identities = 76/204 (37%), Positives = 109/204 (53%), Gaps = 4/204 (1%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP      Q V V SG+  R    ++G     + W K  + +    + K L +   YTLL
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            ++EA+P+D+  Y C A N  G A   A   V +P   +   P  +    PP II PL+D 
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP---EVVSPDQEMPVYPPAIITPLQDT 3354

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            + +EGQ   F C++ G  L  V WY  DK IKPS++F+M++  D Y L I+EA+PEDEG 
Sbjct: 3355 VTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 3413

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPD 4716
            Y  VA N+ G+V+  A L +  P+
Sbjct: 3414 YTFVASNAVGQVSSTANLSLEAPE 3437



 Score =  142 bits (344), Expect = 3e-32
 Identities = 113/391 (28%), Positives = 184/391 (47%), Gaps = 33/391 (8%)

Query: 1836 VEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY- 1893
            VE   +Q  P F+ +L     + EG  +  E ++    +PN  + W  N  ++   H+Y 
Sbjct: 1547 VEAVEHQVKPMFVEKLKN-VNIKEG--SRLEMKVRATGNPNPDIVWLKNSDIIVP-HKYP 1602

Query: 1894 --RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ--------SKESII 1943
              R     G AAL I +   +DS  YT  AIN  G+  +  ++NV+         ++ II
Sbjct: 1603 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1662

Query: 1944 RDSQHESA------LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHL 1997
                + +       LE +       +++     D    +KP F K + +  +    P H 
Sbjct: 1663 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHF 1722

Query: 1998 EATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNA 2057
            E  LTP+ DPTM VEW  +G+P++  +R +   +FGY +LD   AY+ D+G   C+ATN 
Sbjct: 1723 ECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNK 1782

Query: 2058 VGEAVTTSSVKV-DAKSGLYLDTLDEQR--LKKIQELEKYERPKPI----EEEQPGQRPV 2110
             G   T++++ V D KS +    L E R  L++I+ELE+      +     +++  Q+P 
Sbjct: 1783 YGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPD 1842

Query: 2111 FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALD 2170
             +     +  L EG+ A F CRV     P   ++W+ NGQ IR   R+R  +D G   LD
Sbjct: 1843 IVLYPEPVRVL-EGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLD 1898

Query: 2171 ILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            I+   + D+G     A N  G   +   L++
Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929



 Score =  139 bits (337), Expect = 2e-31
 Identities = 118/441 (26%), Positives = 191/441 (43%), Gaps = 29/441 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN--RLTTMHDFGYV 1768
            P+F   +K++ + E   +  E ++   G+P   + WL+N   I      ++      G  
Sbjct: 1556 PMFVEKLKNVNIKEG--SRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1613

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK-ASLQLESQ----------HESA 1817
            AL +     +DS  YT  AIN+ G   T   + V+ + A  + E +           E A
Sbjct: 1614 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1673

Query: 1818 LQKIQQLE---DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874
              +++ L       +++  +  +    Q P F  +L    +L     AH+ECR+ P  DP
Sbjct: 1674 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPIGDP 1732

Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934
             M VEW  +GK L++ +R R  N+FG+ +LD    Y  DSG  TC+A N  G   +S  L
Sbjct: 1733 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1792

Query: 1935 NVQSKESIIRDSQHESALEKIQYLEDDSRYKR-----AVQDDSFVVEKPQFGKPIKNAEV 1989
             V+ ++S++ +SQ     + +Q +E+  R         V  D    +KP      +   V
Sbjct: 1793 IVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1852

Query: 1990 TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGT 2049
             EG        +T    P  +V WY NG+ +++  RF+  YD G   LDI+   + DTG 
Sbjct: 1853 LEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGE 1909

Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRP 2109
                A N   E V    VK++ +      ++  +  +   E   +E  K   E Q   RP
Sbjct: 1910 VKVTAENP--EGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRP 1967

Query: 2110 VFLTALTSLENLKEGDRAHFE 2130
            V  T    +  LK  +R   E
Sbjct: 1968 VDTTETKEVVKLKRAERITHE 1988



 Score =  136 bits (330), Expect = 1e-30
 Identities = 116/410 (28%), Positives = 186/410 (45%), Gaps = 44/410 (10%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F K ++  +V E ++A FE E   EP   ++W +++  ++ +   +I        L+I  
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPS 3118

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              + D+  +  VA     TAK    L VE +  + R            + V V   Q   
Sbjct: 3119 TRMSDAGKYTVVAGGNVSTAK----LFVEGRDVRIRS---------IKKEVQVIEKQRAV 3165

Query: 4533 LDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            ++ +V     +D +W K+G ++  Q   R+K + E   + + I E    D+G+Y  VA  
Sbjct: 3166 VEFEVN-EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA-- 3222

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
              G  R      V+ P               PP++++ L+   V  G+   F   I G+P
Sbjct: 3223 --GRNRSSVTLYVNAPE--------------PPQVLQELQPVTVQSGKPARFCAVISGRP 3266

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P + WYK ++L+      +      EYTL + EAFPED   Y C A N  G  T +A L
Sbjct: 3267 QPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASL 3326

Query: 4711 -----KVTQPDQADNL--PA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                 +V  PDQ   +  PA +TPL+D V  EGQPA+F+ ++ S     + W  +   I 
Sbjct: 3327 SVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIK 3385

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  F+M    +   L I   Y ED GT+T  A+ A GQV ++A L +++
Sbjct: 3386 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435



 Score =  134 bits (324), Expect = 7e-30
 Identities = 128/502 (25%), Positives = 219/502 (43%), Gaps = 32/502 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++  K     HFEC + P  DPT+ +EW  + KPL +  R +  ++F Y SLD 
Sbjct: 1705 FKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDY 1764

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE-AR 2894
               Y  DSGI TC+ATN  G+  TS +L    +K++  ++Q P+G+ GL+ +E+ E  A 
Sbjct: 1765 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1824

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
                   +    E  KP+ I+      +++EG+      +V     P  K+ WY NG+++
Sbjct: 1825 EGALTGVTTDQKEKQKPD-IVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQLI 1881

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN---LIE 3011
             +  RF++  D G   LD+VD    D+G     A N  G       +    +++   ++ 
Sbjct: 1882 RKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLR 1940

Query: 3012 RTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQ-IAHY-- 3068
            R   P+    + +   L+  ++K           RP + TT  K++V +   + I H   
Sbjct: 1941 RAPEPRPEFHVHEPGKLQFEVQK---------VDRPVD-TTETKEVVKLKRAERITHEKV 1990

Query: 3069 --EASLIPTGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMV--VLEILGTKTTDSGTYSC 3123
              E+  + +  +    E +Y   T +E   R +      ++    + L   T +      
Sbjct: 1991 PEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEK 2050

Query: 3124 RATNKWGQAEI-SVKLECVDKSKGQK-PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181
            +A  + G+  I + K + ++ S   + P+    IQ+ + +  G  AHF   VV   DP+ 
Sbjct: 2051 KALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC 2109

Query: 3182 KIEWYHNGQPMRHSTRIKTV-SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
              EWY NG  +  S RI     +     L I      DS   + +A N  GE  + A + 
Sbjct: 2110 --EWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLL 2167

Query: 3241 CYGKGGVYLESLQPDSLAKIRE 3262
               K  +       D +AK ++
Sbjct: 2168 VQAKQLITFTQELQDVVAKEKD 2189



 Score =  128 bits (310), Expect = 4e-28
 Identities = 102/387 (26%), Positives = 167/387 (43%), Gaps = 25/387 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF---RFGY 693
            P F+  LK+V   EG ++  E ++   G+P   I WLKN   I    ++  I      G 
Sbjct: 1556 PMFVEKLKNVNIKEGSRL--EMKVRATGNPNPDIVWLKNSDII-VPHKYPKIRIEGTKGE 1612

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT--------------PRATIERTSQ 739
             +L + S   QDS  YT  A++  G   T+  ++V               PR T      
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 740  HPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSD 799
                L+ +       +++  +  +++  Q+P F + L  L  L+    AHFE +LTP+ D
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPIGD 1731

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PTM VEW  DG+P+ A++R+  I  FGY SL+     + D+G  T RA NK G   ++A+
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791

Query: 860  IRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQI 919
            + V    ++  +  +PE R+ +++                    +  QKP+      + +
Sbjct: 1792 LIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEPV 1850

Query: 920  SIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDA 979
             + EG  A F  R+   G    +V W  +G+ +  S R    ++ G   L I     +D 
Sbjct: 1851 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1907

Query: 980  GHYTCRAYNAIGQATTSANLTIVTKKD 1006
            G     A N  G       L I  ++D
Sbjct: 1908 GEVKVTAENPEGVIEHKVKLEIQQRED 1934



 Score =  127 bits (307), Expect = 9e-28
 Identities = 85/307 (27%), Positives = 136/307 (44%), Gaps = 16/307 (5%)

Query: 66   PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            PGEP+ P F       +  +GG+  F  ++ GNP P V W +   PL    +Y + YN+Q
Sbjct: 1076 PGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1135

Query: 126  TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR----- 180
            TG+  L+I      D GEYT   RN++GE   S  +  E              Y+     
Sbjct: 1136 TGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1195

Query: 181  -----HVSETVEHKAYG--TQGYTTEQSRQTQKVAYTNGTDHSSTDD--FKVDTFEYRLL 231
                  V ET     Y    + Y  EQ+   +K+A       +  +D  F + +FE RL+
Sbjct: 1196 FVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1255

Query: 232  REVSFR-ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLS 290
            +E+ +R    T   + E D +    +D S           + +N ++ EG    F  ++S
Sbjct: 1256 KEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMS 1315

Query: 291  GNPRPRVTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            G P P++ W+K+G+R+ +  ++++        +LR+      D G YT  A N  G  + 
Sbjct: 1316 GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAIC 1375

Query: 350  SGYLAVE 356
            SG L VE
Sbjct: 1376 SGKLYVE 1382



 Score =  118 bits (284), Expect = 5e-25
 Identities = 113/500 (22%), Positives = 208/500 (41%), Gaps = 31/500 (6%)

Query: 4247 IDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIK-ESRL-RESTHQYAI 4304
            +DH  E    +++ P     Q  +  ++EE     Q + +E++ + E R+ +E+  + ++
Sbjct: 3762 VDHSAE---SIVQNPHALSNQMDQNIESEELPTSFQTIVDEEIFQTEIRMSQEALVKESL 3818

Query: 4305 PGDK------VTSNTVAKSMAQRYEDNL---DQTEEVTEQRVQKKVTQKP----RIPDPS 4351
            P D       V  NT A+   +    N    + +  +T    +++V + P    +   P 
Sbjct: 3819 PKDHLYGEILVNENTQARGQLEEIMANTTIGESSTYITNVCEKEEVYETPENVSQAITPH 3878

Query: 4352 ESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE---RVVEGPVK-- 4406
             S   G  V+V + ++   E +   ++     S  T   E K + +E   R  E   +  
Sbjct: 3879 ASESFGTLVNVEESEEIASERIKKDDLRELQLSASTRIDEFKTEQKEENMRFFENSFRKR 3938

Query: 4407 PSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            P + PP F ++++   V+E +   F   F G P P++ WY  + PI  + +F IH+    
Sbjct: 3939 PQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENY 3998

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG-RGGIVP--PSFTLTAQN 4522
            SIL +  V  ++      V  N+ GT K ++ L V+ K++   +   VP    +    + 
Sbjct: 3999 SILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYLDEEEE 4058

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP-QDS 4581
            + +   Q       ++     +++ LK    V P    ++L       +      P QD 
Sbjct: 4059 LALVFDQAKGAHPSMSQEGQTNLHLLKTNPPVPPSGDTELLSFPVEIQVTAATPIPEQDK 4118

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL-KDKIVAEGQAI 4640
               E              + V   P  K +    +   N PP++++ + K     EG +I
Sbjct: 4119 ESKEVFQTEELEPKAMPQDQVTQSP--KHRFVFLSDITNEPPKMLQEMPKHARCREGDSI 4176

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
               C I G+P P V W++   L+K ++ FQ       + L I +   +D G YKCVA N+
Sbjct: 4177 ILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENN 4236

Query: 4701 AGRVTVAAKLKVTQPDQADN 4720
            +G V   + L V      +N
Sbjct: 4237 SGAVESVSDLTVEPVTYREN 4256



 Score =  113 bits (271), Expect = 2e-23
 Identities = 143/649 (22%), Positives = 258/649 (39%), Gaps = 54/649 (8%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH-DFGYVALDILYTYAEDSGT 2181
            EG    F C++     P +   W+ +G++I+ G RY+      G  +L I     ED G 
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIA--WYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361

Query: 2182 YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLEAQGHS-TRIEVEEPK 2238
            Y   A+N  G A+ +  L V     +   T  P    + +IR L  +  S + I +   +
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPAR 1421

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHF--ECQVEPVHDPNLRIEFYHNGKALQS-AARFHITF 2295
            +SP R          +  G+      E Q+E ++ P   ++   + K L+   ARF +  
Sbjct: 1422 MSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV-SFKCLEGQTARFDLKV 1480

Query: 2296 DFGYVSLDIQ-HCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQRPEGLEK 2352
                +      H   +   +Y+ K +       S I +  T    G     +Q   G   
Sbjct: 1481 VGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSS 1540

Query: 2353 IRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEW 2412
            I  + + E  +         + +P+F + L+N+ NI+EG  +  + ++   G+P   + W
Sbjct: 1541 ISVILTVEAVEH--------QVKPMFVEKLKNV-NIKEG--SRLEMKVRATGNPNPDIVW 1589

Query: 2413 FRNEKLIEDSS--RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXX 2470
             +N  +I      +I      G  ++ I     +D   Y   A N  G            
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649

Query: 2471 XXXIQLETQH----PEGMKKIQKLEQP-----HERRSEEP-------DREFE-KPIFTQV 2513
                + E +     P G  + +++  P     H R  +E        D+E + KP F + 
Sbjct: 1650 EFA-EPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1708

Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSV 2573
            LT    L     AH+E R+ P+GDP++  EW  +G  L+  +R R  ++FG+ +LD    
Sbjct: 1709 LTS-LRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVA 1767

Query: 2574 VANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPE-- 2631
             + D+G+  C+A N+ G               +++++  PE  + +Q  E       E  
Sbjct: 1768 YSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGA 1827

Query: 2632 ---MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
               +  D   +Q P    + +   +++EG+      +V     P  K+ W+ NG  +   
Sbjct: 1828 LTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKS 1884

Query: 2689 ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             R +  +D G+  L I   ++ D+G     A N  G       ++I+ R
Sbjct: 1885 KRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1932



 Score =  111 bits (266), Expect = 8e-23
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 11/228 (4%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS--PDFQIHTFSTK 4465
            ++ P FT+ +Q   V E   A FE    G P+P + W+R+   I  S  P  QI     +
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            + L I  V   +S  ++  A N  G A  +A L+V+ +         PP+F    Q++ V
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET-------APPNFVQRLQSMTV 115

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  VRL  +VTG     V + ++G ++Q  +  +I +E   Y+LLI EAYP+DSG Y 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
              A NS G A   AE +V     ++ P  +TK   +  +I E  + +I
Sbjct: 176  VNATNSVGRATSTAELLVQ--GEEEVPAKKTKTIVSTAQISESRQTRI 221



 Score =  109 bits (261), Expect = 3e-22
 Identities = 69/234 (29%), Positives = 108/234 (46%), Gaps = 14/234 (5%)

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            A ++  R   A+ S    +EE        +  P F L   +     GQ  R D KV G  
Sbjct: 1425 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRP 1484

Query: 4542 PIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
              + +W  +G+++  D  +K+ ++EDGT +L+I+ A P DSG++  VA N AG  R    
Sbjct: 1485 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG--RSSIS 1542

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             ++++ A + + KP           +E LK+  + EG  +E   +  G P P + W K  
Sbjct: 1543 VILTVEAVEHQVKPM---------FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNS 1593

Query: 4661 KLIKPSKY--FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +I P KY   ++  T  E  L+I     +D   Y   A N AGR T   K+ V
Sbjct: 1594 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647



 Score =  107 bits (256), Expect = 1e-21
 Identities = 179/750 (23%), Positives = 286/750 (38%), Gaps = 90/750 (12%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYING--VELKMGSRFRTTHDFG 2564
            KP+F + L   + + EG  +  E +V   G+P+    W  N   +      + R     G
Sbjct: 1555 KPMFVEKLKNVN-IKEG--SRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKG 1611

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXX--------IIDQAM-RPES 2615
               L I+S V+ D+  Y   AIN+AG                       II +   R + 
Sbjct: 1612 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKE 1671

Query: 2616 WEQIQLKEAAMNKVPEMF-----VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRT 2670
                +L+   +    E +      D   QQ P F   L S  +L      + E ++ P  
Sbjct: 1672 IAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPIG 1730

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DP + +EW  +G  L    RL+   +FG  +L      + DSGI TC+ATN  G   ++A
Sbjct: 1731 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1790

Query: 2731 SIKIEDRHWLLGESLHPD---SLDRIGALXXXXXXXXXXXXXXXXXXV----FISHLNNI 2783
            ++ ++D   L+ ES  P+    L RI  L                        + +   +
Sbjct: 1791 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1850

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
               EG+   F C V     P  K+ W+ N + +    R++  +D  +  LDI      D+
Sbjct: 1851 RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYDGIHY-LDIVDCKSYDT 1907

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
            G     A N +G                    +H   K  LE ++Q E+ R    R P  
Sbjct: 1908 GEVKVTAENPEGV------------------IEH---KVKLE-IQQREDFRSVLRRAPE- 1944

Query: 2904 PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLK-IEWYFNGKVLEQG----S 2958
                 P+PE+ +    + Q    +V       E K    LK  E   + KV E+     S
Sbjct: 1945 -----PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRS 1999

Query: 2959 RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKG 3018
            +FK  ++ G+   + +   E  S         K+ E++    +   +KD L+  T+  + 
Sbjct: 2000 KFKRRTEEGY--YEAITAVELKS--------RKKDESY--EELLRKTKDELLHWTK--EL 2045

Query: 3019 TEGLEKIQNLEDSLRKEPGQQPDDDTGRPP-EFTTVFKDIVD--ISEGQIAHYEASLIPT 3075
            TE  EK    E+     P  +PD     P  E   +F+ I    + +G  AH+   ++  
Sbjct: 2046 TEE-EKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVV-- 2102

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAEI 3134
            G      EW+ NG  IE S RI   +    V  L I      DS +   +A N  G+   
Sbjct: 2103 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2162

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L    K   Q   FT  +Q++   +    A FEC      +P +K++WY +G  +  
Sbjct: 2163 HAFLLVQAK---QLITFTQELQDVVAKEKDTMATFEC---ETSEPFVKVKWYKDGMEVHE 2216

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              + +  SD     L I      D+ +Y C
Sbjct: 2217 GDKYRMHSDRKVHFLSILTIDTSDAEDYSC 2246



 Score =  105 bits (251), Expect = 5e-21
 Identities = 110/421 (26%), Positives = 164/421 (38%), Gaps = 28/421 (6%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129
            PP F +     +  +     F  ++ G P P V W R K+ L    +  M   E+ G+V 
Sbjct: 5182 PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKM---ERVGNVC 5238

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEA--ICSVYIQPEGXXXXXXXXXXXXXYRHVSE--- 184
            SL I  I  G+ GEY C A N  GEA    +V I P+              ++HV E   
Sbjct: 5239 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQ--EERVVALPPPVTHQHVMEFDL 5296

Query: 185  --TVEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
              T   +    Q    E     + V  +       +  +F  D     +  +V     + 
Sbjct: 5297 EHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPDHKSMIVSLDVLPFNFVD 5356

Query: 242  KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
                         +ID  +  + PP+      + K+ E +DA F+  + G P P V W+K
Sbjct: 5357 PNMDSREGEDKELKIDLEVFEM-PPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYK 5415

Query: 302  NGQRLINSN-KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
                +   N K+ I       TL++RN   SDS  Y   A N  G  +  G+L +     
Sbjct: 5416 EYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEI 5475

Query: 361  SYVQDQRSQYITDTQQRE-------TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
              V  ++S+    +   E       T+   E       P+F+K   D     G    F C
Sbjct: 5476 FAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC 5535

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN--HALMITNVTLSDSGVVTCVARNKS 471
             V G P P V W+ + + ++     +  V ESG   H L IT++  SD G   CVA NKS
Sbjct: 5536 LVRGSPRPTVYWYKDGKLVQ---GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKS 5592

Query: 472  G 472
            G
Sbjct: 5593 G 5593



 Score =  104 bits (249), Expect = 9e-21
 Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 19/258 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN--KILEEDGTYTL 4571
            P+FT   Q+V V  G     +  ++G    +V W ++G+ +        +I   DG   L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      +SG+Y   A N +G+A   AE +V             KA  APP  ++ L+ 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------KAETAPPNFVQRLQS 112

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V +G  +    ++ G P P V++Y+    I+ S  FQ+S+  D Y+L I+EA+PED G
Sbjct: 113  MTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK-- 4749
             Y   A NS GR T  A+L V   ++       T +    + E +  + + +I +     
Sbjct: 173  TYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDAR 232

Query: 4750 --PTIQWLREGALIPETP 4765
               T++ + +GA   + P
Sbjct: 233  SIATVEMVIDGAAGQQLP 250



 Score =  102 bits (244), Expect = 4e-20
 Identities = 70/234 (29%), Positives = 108/234 (46%), Gaps = 16/234 (6%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV+PP +    +N  + EG     +  +SG P P VTW++   ++ +S   +I       
Sbjct: 939  PVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIA 998

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE----------SPTESYVQDQR---- 367
             L +R     DSG +T  A N  G + TS YLAV+          + TE +  +++    
Sbjct: 999  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1058

Query: 368  SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            S+ +  T    TEE+    E A AP F+     + + EG    F C+V G P P V W  
Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPA-APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1117

Query: 428  NDRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            +   +   Y +K+  N ++G   L+I+     D+G  T V RNK GET+    L
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score =  100 bits (240), Expect = 1e-19
 Identities = 76/284 (26%), Positives = 123/284 (43%), Gaps = 8/284 (2%)

Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITS----T 4385
            +EV     Q+ V +     D  ++  +   + +  Q Q + + V ++ I R   S    +
Sbjct: 3154 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3213

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445
            +  E    A      V   V   +PP   +++QP  V   + ARF     G P P I WY
Sbjct: 3214 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3273

Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR- 4504
            +E   +      +      +  L++ + F ED+AV+   A+N  G A  SA+L VE    
Sbjct: 3274 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3333

Query: 4505 --RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                    + PP+     Q+   + GQ  R   +V+GT  + V W    KK++P    ++
Sbjct: 3334 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRM 3392

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
             + + TY L I EAYP+D G Y  VA N+ G+    A   +  P
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 57/193 (29%), Positives = 97/193 (50%), Gaps = 4/193 (2%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYTL 4680
            P   +PL+  +V EG    F   I G P+P V W++  ++I  S     Q+S +     L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             I      + G Y   A N +G+ T  A+L V       N   +  L+ + V +G   + 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNF--VQRLQSMTVRQGSQVRL 123

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + ++T    P +++ R+GA I  + DFQ+  EG+   LLI   Y ED+GT++  AT + G
Sbjct: 124  QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183

Query: 4801 QVETSAKLVVKSK 4813
            +  ++A+L+V+ +
Sbjct: 184  RATSTAELLVQGE 196



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 60/189 (31%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F +  Q   V EG    F+  ++G P PEV+WF + + I       + ++ S   A 
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I  VT ++SG  +  A N SG+      L V  K +   P FV+R  ++ VR+G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV--KAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L  R  G PTP + + +DG  I  + + +I  +G   +L I  A   D+  Y   A N  
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182

Query: 570 GSTATRARL 578
           G   + A L
Sbjct: 183 GRATSTAEL 191



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 114/474 (24%), Positives = 192/474 (40%), Gaps = 66/474 (13%)

Query: 3643 VSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETL---HKREEITIEDEKPNPPRFTV 3699
            +    QV+ R   ++E ++   F S T      E T      R  +T+    P PP+   
Sbjct: 3184 IEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQ 3243

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
            E++  + V  G P  F C V   G P  +I W+   +  +TG +   L+D     L +  
Sbjct: 3244 ELQP-VTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE 3300

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
             +  DA  YTC A N +G ATT+A           L  ++P+ +S +             
Sbjct: 3301 AFPEDAAVYTCEAKNDYGVATTSAS----------LSVEVPEVVSPD------------- 3337

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
             +E P+   PP  IT ++     E +  RF+CRV   +   L++ WY   K +     +R
Sbjct: 3338 -QEMPVY--PPAIITPLQDTVTSEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFR 3391

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR--GM 3937
                     L+I   Y ED G Y   A N  G+  + A +S  + P+ IL  ++ +   M
Sbjct: 3392 MTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL-EAPESILHERIEQEIEM 3450

Query: 3938 KRSEALTQMEAT-IKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTS------------ 3984
            +  E  ++ E+   ++ T + +   +D+ D       R+ ++I S +S            
Sbjct: 3451 EMKELFSEGESEHSERDTRDAFSDSEDI-DHKSMAAKRYASRISSTSSWPEYFKPSFTQK 3509

Query: 3985 -----LVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR--FTPIYDFGY--VAMNF 4035
                 ++E E   F C+L  +  P  ++ WF N +P+    R       D  +   ++  
Sbjct: 3510 LTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEI 3567

Query: 4036 GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE 4089
              V   DSG Y   A N  G  E+ A +    K     D +  + +K  E+  E
Sbjct: 3568 KRVQDRDSGSYRLLAINSEGSAESTASLLVIQKG---QDEKYLEFLKRAERTHE 3618



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 105/422 (24%), Positives = 177/422 (41%), Gaps = 54/422 (12%)

Query: 4389 EIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN 4448
            E E+   T + +VEG V       F K++Q   V E      E     E +   KWY  +
Sbjct: 2250 EDENVKTTAKLIVEGAVVE-----FVKELQDIEVPESYSGELECIVSPENIEG-KWYHND 2303

Query: 4449 FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              +K++  + I +   +  L ++ V  ED   ++ V + +  T K      ++ K R   
Sbjct: 2304 VELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCK------LKMKPR--- 2354

Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568
                P +      +  V  G +V+L+ KV+  + ++  W+K+G++VQP  R  I+ +  +
Sbjct: 2355 ----PIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQS 2409

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            + LLI +   +D+G Y    I + G +      V S+                  ++I P
Sbjct: 2410 HMLLIEDMTKEDAGNYS-FTIPALGLSTSGRVSVYSV------------------DVITP 2450

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            LKD  V EG      CK+    + +V+WY  D+ IKP    Q      +  L I+     
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2510

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            DEG YK +     GRV     L V      + +  +  LRD+   E Q   F+ ++ S  
Sbjct: 2511 DEGPYKLI----VGRVETNCNLSV------EKIKIIRGLRDLTCTETQNVVFEVEL-SHS 2559

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
               + W  +   I  +  +++   G    L + N  ++D G +    T  AG+  TS KL
Sbjct: 2560 GIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKY----TFYAGENMTSGKL 2615

Query: 4809 VV 4810
             V
Sbjct: 2616 TV 2617



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 105/404 (25%), Positives = 168/404 (41%), Gaps = 44/404 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P + T  ++     E +   FEV  + E +   KW +    IK++   Q+ T      L 
Sbjct: 2968 PIMITSMLKDINAEEKDTITFEVTVNYEGISY-KWLKNGVEIKSTDKCQMRTKKLTHSLN 3026

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            IR V   D+A +  VA    G A  +A L VE +  + R  I         +++ V   +
Sbjct: 3027 IRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHI---------KDIKVLEKK 3073

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
                + +V+    I V W+K+ +++Q   R KI +E   + LLI      D+GKY  VA 
Sbjct: 3074 RAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAG 3132

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
             +   A+   E        +D    + ++     ++IE  K + V     +EF    V +
Sbjct: 3133 GNVSTAKLFVE-------GRD---VRIRSIKKEVQVIE--KQRAV-----VEFE---VNE 3172

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                  WYK    I      +     +   + + ISE    D G+Y  V    AGR   +
Sbjct: 3173 DDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV----AGRNRSS 3228

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              L V  P+    L  L P   + V  G+PA+F   I+ + +P I W +E  L+      
Sbjct: 3229 VTLYVNAPEPPQVLQELQP---VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3285

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + +H+G    LL+   + ED   +TC A    G   TSA L V+
Sbjct: 3286 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 71/236 (30%), Positives = 110/236 (46%), Gaps = 10/236 (4%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMH 1763
            EV    P F MP+ D ++ EN  A F+  +I +  P+  V+W +  + IE  N +     
Sbjct: 5374 EVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISE 5431

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-QSKASLQLESQHESALQKI- 1821
            + G   L ++ V   DS TY CRA+N +GEA+    L +  S+    +  + +  L  + 
Sbjct: 5432 EKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLM 5491

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            ++L   S Y         V   PRFI  ++       G +A+++C +   P P   V WY
Sbjct: 5492 EELVLKSNYTDSFFEFQVVEGPPRFIKGISD-CYAPIGTAAYFQCLVRGSPRPT--VYWY 5548

Query: 1882 FNGKVLQSGHRYRTSND-FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +GK++Q G R+       GF  L I ++   D GEY C A N  G A S   L +
Sbjct: 5549 KDGKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 92/396 (23%), Positives = 164/396 (41%), Gaps = 64/396 (16%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E PQ  + ++   V  G P    A ++    P  ++ WY   + +  G + K  +D    
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L ++ A+ ED   Y C+A N  G A T++S+ V                    E+ +  
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------------------EVPEVV 3334

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
             P   ++E P   P  +T L       EG  A F+CRV   +   L + W+   +KI+  
Sbjct: 3335 SP---DQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPS 3387

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN 2215
              +R T       L+I   Y ED GTY   A+N +G+  +T  L +    +I+ +     
Sbjct: 3388 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447

Query: 2216 GLEKIRQLEAQG---HSTR---------IEVEEPKISPPRFVTELRGTT----------- 2252
               ++++L ++G   HS R          +++   ++  R+ + +  T+           
Sbjct: 3448 IEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFT 3507

Query: 2253 ------HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY----VSL 2302
                  +V EG+   F C++  +  P   + ++HN + + +  R  I  +        SL
Sbjct: 3508 QKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSL 3565

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKG 2338
            +I+     D+G Y + AIN+ G   S  S+ V  KG
Sbjct: 3566 EIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKG 3601



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/224 (29%), Positives = 98/224 (43%), Gaps = 12/224 (5%)

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDF 4457
            E   E  ++    P+F  K    +  E + ARF+++  G P+P   W+ +   I N    
Sbjct: 1444 EETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTH 1503

Query: 4458 Q--IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
            +  I    T+S++I+      DS  +  VA+NR G +  S  L VE    Q     V P 
Sbjct: 1504 KVVIKEDGTQSLIIV-PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQ-----VKPM 1557

Query: 4516 FTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLI 4573
            F    +NVN+  G  + +  + TG    D+ WLKN   + P    KI  E   G   L I
Sbjct: 1558 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKI 1617

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                 QDS  Y   AIN AG  R    C V++     +P+P+ K
Sbjct: 1618 DSTVSQDSAWYTATAINKAG--RDTTRCKVNVEVEFAEPEPERK 1659



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 105/467 (22%), Positives = 175/467 (37%), Gaps = 46/467 (9%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   +     K+ E     F V++ G P P V W++N   L    + ++    N  +L 
Sbjct: 5182 PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLE 5241

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            + N QK + G Y   A N  G   +   + +  P E  V          T Q   E  +E
Sbjct: 5242 ISNIQKGEGGEYMCHAVNIIGEAKSFANVDI-MPQEERVVALPPPV---THQHVMEFDLE 5297

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
             +  +  P   ++  + +++E  +  F+ +V     PE T                    
Sbjct: 5298 HTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFT-------------------- 5337

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETA-FQCRLNVIEKEQVVAPKFVERFSTLNVR 503
              +H  MI ++ +     V     ++ GE    +  L V E    + P+F+       + 
Sbjct: 5338 -PDHKSMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFE----MPPRFIMPICDFKIP 5392

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQ 562
            E    V     +G PTP + W K+ + I P N +  I  + G+ TL I     SD+A Y+
Sbjct: 5393 ENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYR 5452

Query: 563  CTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERAR 622
            C A N  G    R  L            K+  +   + +            +        
Sbjct: 5453 CRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFF------- 5505

Query: 623  PYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEAS 682
                  E   V  PP+FI  +    A  G   +F+  +   G P   + W K+G+ ++  
Sbjct: 5506 ------EFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVR--GSPRPTVYWYKDGKLVQGR 5557

Query: 683  SRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
                     G+ +L + SL   D GEY C A + +G+AE+ A L +T
Sbjct: 5558 RFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 103/397 (25%), Positives = 165/397 (41%), Gaps = 66/397 (16%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P     ++ + V   + A F A  +  G P+ ++ W +    +    +   +HD    
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCA--VISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L +    PED+  YTC A N+ G A TS        ASL +E     +           
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGVATTS--------ASLSVEVPEVVS----------- 3335

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
                  D E+ V   P  IT L   T  SEGQ A ++CR+      +++V WY   K ++
Sbjct: 3336 -----PDQEMPV-YPPAIITPLQD-TVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIK 3385

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS-Q 1947
                +R +       L+I   Y ED G YT  A N +GQ  S+  L++++ ESI+ +  +
Sbjct: 3386 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIE 3445

Query: 1948 HESALE-KIQYLEDDSRYKRAVQDDSFVVEK----------------------PQFGKPI 1984
             E  +E K  + E +S +      D+F   +                      P++ KP 
Sbjct: 3446 QEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPS 3505

Query: 1985 KNAEVT-----EGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFGY--V 2035
               ++T     EG PV     L  +  PT  + W+ N RP+  G R   K   D  +   
Sbjct: 3506 FTQKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            +L+I      D+G+Y   A N+ G A +T+S+ V  K
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 79/297 (26%), Positives = 132/297 (44%), Gaps = 23/297 (7%)

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITV-MQAPQFSRALHNIETVEGTNVHLECR 1333
            I   T  E+  E +   E     T +V   + + +  P     L N+  +EG +V LEC 
Sbjct: 906  ITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECH 965

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            +   G  +  V W+     I++   F+  ++     L +   + EDSG +TC A N+ G 
Sbjct: 966  IS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023

Query: 1394 AVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII--DESVT---------I 1442
              TSC L V   ++   E +  +  EK    E+    +  D++  D S+T          
Sbjct: 1024 VSTSCYLAVQVSEE--FEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLTEEQAGPGEPA 1080

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD--FG 1500
             P F+T+P  ++ ++EG  V F C++    +    V W K+G P+T G+R++  ++   G
Sbjct: 1081 APYFITKP-VVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1137

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
               L I    A+D+G YT    N  G    S  L   +  +++  +Q E  L Q QV
Sbjct: 1138 ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEM-LYQTQV 1193



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 77/263 (29%), Positives = 112/263 (42%), Gaps = 19/263 (7%)

Query: 1699 RHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            R  A  E+    P     +K++ V E ++   E  +   G P   V W R    IE+S  
Sbjct: 931  RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSID 988

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
                   G   L ++    EDSG +TC A+NE G   TS  L VQ   S + E +  +  
Sbjct: 989  FQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--VSEEFEKETTAVT 1046

Query: 1819 QKIQQLED---SSRYQRREDVEVAVNQ-------APRFITQLNGPTKLSEGQSAHYECRI 1868
            +K    E     SR     D  +   Q       AP FIT+     KL EG S  + C++
Sbjct: 1047 EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQV 1105

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTS--NDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
               P P+  V W  +G  L +G+RY+ S     G   L I   + +D+GEYT    N  G
Sbjct: 1106 GGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1163

Query: 1927 QAVSSIRLNVQSKESIIRDSQHE 1949
            +  +S  L  ++   ++  SQ E
Sbjct: 1164 ETSASASLLEEADYELLMKSQQE 1186



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 116/517 (22%), Positives = 208/517 (40%), Gaps = 48/517 (9%)

Query: 4307 DKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQK 4366
            D+    T  K + +         E+V E+  + +   K R  +     +   E+   K+ 
Sbjct: 1965 DRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKD 2024

Query: 4367 QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPV-KPSK---------PPIFTKK 4416
            ++ +E++   +      + E TE E KA  +E  +  P  KP K         P IF ++
Sbjct: 2025 ESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIF-ER 2083

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSILIIRQVFV 4475
            +Q   V +   A F V   G+P P  +WY+    I+ S   +          L+IR V  
Sbjct: 2084 IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTA 2143

Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            EDSA     A N  G     A L+V+ K+      ++  +FT   Q+V       +    
Sbjct: 2144 EDSASIMVKAINIAGETSSHAFLLVQAKQ------LI--TFTQELQDVVAKEKDTMATFE 2195

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T    + V W K+G +V    + ++  +   + L IL     D+  Y CV +      
Sbjct: 2196 CETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NV 2254

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
            +  A+ +V                 A  E ++ L+D  V E  + E  C IV       +
Sbjct: 2255 KTTAKLIVE---------------GAVVEFVKELQDIEVPESYSGELEC-IVSPENIEGK 2298

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            WY  D  +K +  + ++       L + +   ED+G+Y  V      + T   K+K  +P
Sbjct: 2299 WYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMK-PRP 2355

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                 +  L  L D  V EG   Q + +++ +    + W+++G  +  +    ++ +  +
Sbjct: 2356 -----IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQS 2409

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +LLI +  +ED G ++   T  A  + TS ++ V S
Sbjct: 2410 HMLLIEDMTKEDAGNYS--FTIPALGLSTSGRVSVYS 2444



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 65/228 (28%), Positives = 95/228 (41%), Gaps = 27/228 (11%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD-IRNKILEEDGTYT 4570
            +PP F +   +  +           V G    +V W K    ++PD I+  I EE G++T
Sbjct: 5378 MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHT 5437

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARC-------DAECVVSLPATKDKPKPQT------- 4616
            L I      DS  Y C A+N  GEA C       D+E + ++ A K K    +       
Sbjct: 5438 LKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSE-IFAVIAKKSKVTLSSLMEELVL 5496

Query: 4617 -----------KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                       +    PP  I+ + D     G A  F C + G P PTV WYK  KL++ 
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQG 5556

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             ++         + L I+     DEG+Y+CVA N +G     A L +T
Sbjct: 5557 RRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 73/261 (27%), Positives = 114/261 (43%), Gaps = 14/261 (5%)

Query: 3803 MSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            + G + K  E  R+  AP E P+  TPP  ++ +K+ TV E E V  EC +     P   
Sbjct: 919  LHGREAKVTETARVP-APVEIPV--TPPTLVSGLKNVTVIEGESVTLECHISGYPSPT-- 973

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            + WYR    + S   ++  +  G   L I   +AEDSG + C AVN+ G   T   ++ +
Sbjct: 974  VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033

Query: 3923 KLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQ 3982
               +   +         +E    +E+     T +  LTE+      +   P F+T+   Q
Sbjct: 1034 VSEEFEKETTAVTEKFTTEEKRFVESRDVVMT-DTSLTEEQA-GPGEPAAPYFITKPVVQ 1091

Query: 3983 TSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD--FGYVAMNFGWVYP 4040
              LVE  +  F CQ+   G+P   V W  +G PL    R+   Y+   G   +     + 
Sbjct: 1092 -KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFA 1148

Query: 4041 EDSGEYLCRATNLYGMDETKA 4061
            +D+GEY     N +G  ET A
Sbjct: 1149 DDAGEYTIVVRNKHG--ETSA 1167



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 22/283 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            VE+ V   P  ++ L   T + EG+S   EC I  YP P   V WY     ++S   ++ 
Sbjct: 936  VEIPVTP-PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQI 991

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            +   G A L I   + EDSG +TC A+N  G   +S  L VQ  E    + +  +  EK 
Sbjct: 992  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF--EKETTAVTEK- 1048

Query: 1956 QYLEDDSRYKRA----VQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPV------N 2005
             +  ++ R+  +    + D S   E+   G+P     +T+     L    + V       
Sbjct: 1049 -FTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1107

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYD--FGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            +P   V W  +G P+  G+R+K +Y+   G   L I   +A+D G Y     N  GE   
Sbjct: 1108 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSA 1167

Query: 2064 TSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPG 2106
            ++S+  +A   L + +  ++ L + Q     + PK + E  PG
Sbjct: 1168 SASLLEEADYELLMKS-QQEMLYQTQVTAFVQEPK-VGETAPG 1208



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 130/525 (24%), Positives = 210/525 (40%), Gaps = 76/525 (14%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            GR     ++ K+ V + E Q A  E  +    +  +   W+ +G  I    + R  Y   
Sbjct: 3144 GRDVRIRSIKKE-VQVIEKQRAVVEFEV---NEDDVDAHWYKDGIEINFQVQERHKYVVE 3199

Query: 3105 MVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
              +  + I  T+ +D+G Y+  A    G+   SV L     +  + P+    +Q +  ++
Sbjct: 3200 RRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV---NAPEPPQVLQELQPVT-VQ 3251

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G+ A F C V+    P  KI WY   Q +    + K + D     L +      D+  Y
Sbjct: 3252 SGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVY 3309

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282
             C A N YG   T A+++                     E+  +    Q+ P      PP
Sbjct: 3310 TCEAKNDYGVATTSASLSV--------------------EVPEVVSPDQEMP----VYPP 3345

Query: 3283 KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
              IT +QD T   EGQ A F+ R   V   DLKV W+   KK+     +R         L
Sbjct: 3346 AIITPLQD-TVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQL 3401

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLED 3402
            +I   Y E+ G Y  VA+N +G+ S+ ANL   + E+ IL  ++ + +E  +++L +  +
Sbjct: 3402 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES-ILHERIEQEIEMEMKELFSEGE 3460

Query: 3403 SMVRRKDT--------SVEEEKGKAPVFTVPLSNIEN-----------------LREGEN 3437
            S    +DT         ++ +   A  +   +S+  +                 + EGE 
Sbjct: 3461 SEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEP 3520

Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGSR--FRTFCDFGF--VILEISPTYPEDSGEY 3493
              F  RL     P  ++ W+ N + +  G R   +   D       LEI      DSG Y
Sbjct: 3521 VVFTCRLIACPTP--EMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSY 3578

Query: 3494 LCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
               A N+ G A +TAS+ V  K       +  K  E T + + AL
Sbjct: 3579 RLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAERTHENVEAL 3623



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 89/379 (23%), Positives = 159/379 (41%), Gaps = 28/379 (7%)

Query: 4360 VHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQP 4419
            V V+++ + +   V +K  T +    E+ ++     +      GP +P+ P   TK +  
Sbjct: 1032 VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQ 1091

Query: 4420 CRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSILIIRQVFVED 4477
             ++ E     F  +  G P P + W +   P+     +++  +  + +  L+I   F +D
Sbjct: 1092 -KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADD 1150

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            +  +  V  N+ G    SA+L+ E         ++  S         VT+   V+ + KV
Sbjct: 1151 AGEYTIVVRNKHGETSASASLLEEADYE-----LLMKSQQEMLYQTQVTA--FVQ-EPKV 1202

Query: 4538 TGTKPIDVY--WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T P  VY  + K  +K Q  IR K+ ++      +++  Y +D  ++   +       
Sbjct: 1203 GETAPGFVYSEYEKEYEKEQALIRKKMAKDT-----VVVRTYVEDQ-EFHISSFEERLIK 1256

Query: 4596 RCDAECV-VSLPATKDKPKPQTKAAN-APPEIIEP-----LKDKIVAEGQAIEFSCKIVG 4648
              +   +  +L    ++   +  A + +  E +E      +K+  + EG  + F CK+ G
Sbjct: 1257 EIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSG 1316

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             PLP + WYK  K IK  + +QM    D   +LRI    PEDEG Y   A N  G    +
Sbjct: 1317 YPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICS 1376

Query: 4708 AKLKVTQPDQADNLPALTP 4726
             KL V +P      P   P
Sbjct: 1377 GKLYV-EPAAPLGAPTYIP 1394



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 67/227 (29%), Positives = 98/227 (43%), Gaps = 7/227 (3%)

Query: 4315 AKSMAQRYEDNLDQ-TEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVV 4373
            A S AQ+   ++   T + +E RV+ + T  P+ P       +  E  V  +K+    + 
Sbjct: 848  ATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSIT 907

Query: 4374 GDKEITRKITSTETTEIEHKAQTQERVVEGPVK-PSKPPIFTKKMQPCRVFEHEQARFEV 4432
            G    T +    E         T+   V  PV+ P  PP     ++   V E E    E 
Sbjct: 908  GT---TVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
               G P P + WYRE++ I++S DFQI   S  + L+IR+ F EDS  F   A N  GT 
Sbjct: 965  HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 1024

Query: 4493 KCSANLVVE-EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
              S  L V+  +  +     V   FT T +   V S  +V  DT +T
Sbjct: 1025 STSCYLAVQVSEEFEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLT 1070



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 71/236 (30%), Positives = 106/236 (44%), Gaps = 17/236 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP  +  LK+VT +EG  +  E  I   G P+  + W +    IE+S  F   F+ G   
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIAR 999

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIER-TSQHPE--TLQYIQQLED 752
            L +     +DSG +TC AV+  G   T   L V      E+ T+   E  T +  + +E 
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059

Query: 753  YSKYQHQESIEEQTS-----QRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
                    S+ E+ +       P FI +P+  + +L EG +  F  Q+    +P   V W
Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVEGGSVVFGCQVG--GNPKPHVYW 1115

Query: 807  YKDGRPITASSRITSIFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
             K G P+T   R    +N   G   L I    A+DAG YT+   NK GE  ++AS+
Sbjct: 1116 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 87/347 (25%), Positives = 143/347 (41%), Gaps = 29/347 (8%)

Query: 242  KRYVGESDVQIS-TEI-DRSLGPVSP--PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
            KR+V   DV ++ T + +   GP  P  P    KP   KL EG    F  Q+ GNP+P V
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113

Query: 298  TWFKNGQRLINSNKHEIITTHNHTT----LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
             W K+G  L    ++++  ++N  T    L +  T   D+G YT++  N +G    S  L
Sbjct: 1114 YWKKSGVPLTTGYRYKV--SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171

Query: 354  AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
              E+  E  ++ Q+ + +  TQ     +  ++ E   AP FV    +++    K      
Sbjct: 1172 LEEADYELLMKSQQ-EMLYQTQVTAFVQEPKVGE--TAPGFVYSEYEKEYE--KEQALIR 1226

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
            +   +    V  ++ D++       + L+ E       I   TL +          + GE
Sbjct: 1227 KKMAKDTVVVRTYVEDQEFHISSFEERLIKEI---EYRIIKTTLEE-------LLEEDGE 1276

Query: 474  TAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
               +  +++ E E  V   F  R     + EG  V  + +  G P P+I W KDG  I  
Sbjct: 1277 E--KMAVDISESE-AVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKH 1333

Query: 534  NPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
                ++     G ++L IP     D   Y   A N+ G+     +LY
Sbjct: 1334 GERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLY 1380



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 99/387 (25%), Positives = 153/387 (39%), Gaps = 67/387 (17%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++ G  A F A +   G    ++ W K+ + +    +     +     L +      D
Sbjct: 3248 VTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 3305

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK 1038
            A  YTC A N  G ATTSA+L++   + +  + + P                        
Sbjct: 3306 AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP------------------------ 3341

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
                P  + PL+ T    EGQ A F+ RV   S   + V WY   K+I  +   +     
Sbjct: 3342 -VYPPAIITPLQDT-VTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFE 3396

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI----------------- 1141
                L+IA    ED G YT VA NA G+   +A++++E   SI                 
Sbjct: 3397 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELF 3456

Query: 1142 -DTSSIH-----RGLYEKTRHIEESKFVEPMYQIEEISKS------KPVFVQPLSNPPPV 1189
             +  S H     R  +  +  I+        Y     S S      KP F Q L+    V
Sbjct: 3457 SEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTF-KYV 3515

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR--FKTYYDFGF--VALDIIHATSA 1245
             EG+ +   CRL  +  PT  + WFHN R +  G R   K   D      +L+I      
Sbjct: 3516 LEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDR 3573

Query: 1246 DTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            D+G Y + A+N  GSA ++A + VI++
Sbjct: 3574 DSGSYRLLAINSEGSAESTASLLVIQK 3600



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 52/206 (25%), Positives = 97/206 (47%), Gaps = 4/206 (1%)

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSK 4667
            ++  + Q +    P  +++P+  K + EGQ   F  K+VG+P+P   W+  G +++    
Sbjct: 1444 EETDESQLERLYKPVFVLKPVSFKCL-EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYT 1502

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +  + +     +L I  A P D G++  VA N AGR +++  L V   +       +  L
Sbjct: 1503 HKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKL 1562

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI--PETPDFQMIHEGNNAVLLIGNTYE 4785
            +++ + EG   + K + T    P I WL+   +I   + P  ++      A L I +T  
Sbjct: 1563 KNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVS 1622

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            +D+  +T  A   AG+  T  K+ V+
Sbjct: 1623 QDSAWYTATAINKAGRDTTRCKVNVE 1648



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 62/263 (23%), Positives = 119/263 (45%), Gaps = 33/263 (12%)

Query: 1831 QRREDVEVAVN--QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
            + R  V + VN  + P+ + +L  P  +  G+ A +   I   P P  ++ WY   ++L 
Sbjct: 3224 RNRSSVTLYVNAPEPPQVLQELQ-PVTVQSGKPARFCAVISGRPQP--KISWYKEEQLLS 3280

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
            +G + +  +D     L ++  + ED+  YTC+A N+ G A +S  L+V+  E +      
Sbjct: 3281 TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVS----- 3335

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008
                                 D    V  P    P+++   +EG P   +     V+   
Sbjct: 3336 --------------------PDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTD 3372

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            ++V WY   + ++    F+ T       L+I  AY ED GTY   A+NAVG+  +T+++ 
Sbjct: 3373 LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 3432

Query: 2069 VDAKSGLYLDTLDEQRLKKIQEL 2091
            ++A   +  + ++++   +++EL
Sbjct: 3433 LEAPESILHERIEQEIEMEMKEL 3455



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 76/271 (28%), Positives = 117/271 (43%), Gaps = 38/271 (14%)

Query: 3546 DTLTPEAESG-NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            + ++P+ E    PP   T   D + SE   A F+CR   V+ + ++V W+   K +   S
Sbjct: 3332 EVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP-S 3387

Query: 3605 RVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGII------- 3656
            R   +  F     LEI   Y  D G YT  A+N  G+ + +  L ++  + I+       
Sbjct: 3388 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447

Query: 3657 LEPQLPSHFKSG---------TESIQKLEETLHK-------REEITIEDEKPN--PPRFT 3698
            +E ++   F  G          ++    E+  HK          I+     P    P FT
Sbjct: 3448 IEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFT 3507

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGF--IA 3754
             ++     V EG PV F CR+  +  PT  + WFHN RP  TG R  +   +D      +
Sbjct: 3508 QKLTFKY-VLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSS 3564

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L+I  +  RD+G Y   A N  GSA +TA +
Sbjct: 3565 LEIKRVQDRDSGSYRLLAINSEGSAESTASL 3595



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 62/240 (25%), Positives = 105/240 (43%), Gaps = 23/240 (9%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP++ Q+ +   +Q G  A+F   +SG P+P+++W+K  Q L    K + +      TL 
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +      D+  YT  A+N  G   TS  L+VE P E    DQ                  
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP-EVVSPDQEM---------------- 3340

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P  +   QD   +EG+  RF CRV+G    +V+W+  D++I+     ++   E
Sbjct: 3341 ---PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFE 3396

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
               + L I      D G  T VA N  G+ +    L++   E ++  + +E+   + ++E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHER-IEQEIEMEMKE 3454



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 101/454 (22%), Positives = 172/454 (37%), Gaps = 58/454 (12%)

Query: 4396 TQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP 4455
            T    +E P     PP F + +   +V+E+    F VE +G P+P +KWYR    ++  P
Sbjct: 5169 TPNEAIE-PKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLE--P 5225

Query: 4456 DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
            D +I      ++          S   + + +  GG   C A  ++ E +      I+P  
Sbjct: 5226 DERIKMERVGNVC---------SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQE 5276

Query: 4516 FTLTAQNVNVTSGQLVRLDTKVTGTK--PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
              + A    VT   ++  D + T +   P     +   +  + D++    E +    ++ 
Sbjct: 5277 ERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLEVELSEKDVK----EFEKQVKIVT 5332

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
            +  +  D  K   V+++       D   + S      + K   +    PP  I P+ D  
Sbjct: 5333 VPEFTPDH-KSMIVSLDVLPFNFVDPN-MDSREGEDKELKIDLEVFEMPPRFIMPICDFK 5390

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY-FQMSRTADEYTLRISEAFPEDEGD 4692
            + E     F C ++G P P V+WYK    I+P    + +S     +TL+I      D   
Sbjct: 5391 IPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSAT 5450

Query: 4693 YKCVAYNSAGR---------------VTVAAKLKVTQPDQADNLPALTPLRD----IVVY 4733
            Y+C A N  G                  +A K KVT     + L   +   D      V 
Sbjct: 5451 YRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVV 5510

Query: 4734 EGQP----------------AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN-A 4776
            EG P                A F+  +    +PT+ W ++G L+ +   F +   G    
Sbjct: 5511 EGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRRFTVEESGTGFH 5569

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L I +  + D G + C AT  +G  E+ A L +
Sbjct: 5570 NLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 78/308 (25%), Positives = 130/308 (42%), Gaps = 41/308 (13%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
            GR  +         ++VNV  G    L+ KV+      V W  N ++++PD R + + + 
Sbjct: 2438 GRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2497

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
                L+I   +  D G Y+ +        R +  C +S+   K               II
Sbjct: 2498 TKQRLVINRTHASDEGPYKLIV------GRVETNCNLSVEKIK---------------II 2536

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              L+D    E Q + F  ++    +  V W   DK IKPS  +++      Y L +    
Sbjct: 2537 RGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMM 2595

Query: 4687 PEDEGDYKCVAYNS--AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
             +DEG Y   A  +  +G++TVA                  PL D  V E Q A F+ ++
Sbjct: 2596 KDDEGKYTFYAGENMTSGKLTVAGGA------------ISKPLTDQTVAESQEAVFECEV 2643

Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
             +      +WLR+G  +P T + +   +G+   L+I  T  +D G +T +  T+    +T
Sbjct: 2644 ANPDSKG-EWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KT 2698

Query: 4805 SAKLVVKS 4812
            SAKL V++
Sbjct: 2699 SAKLKVEA 2706



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 96/398 (24%), Positives = 164/398 (41%), Gaps = 68/398 (17%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + P     L+ V ++ G+ A F    +       K+ WY   + L +G +    ++    
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARF--CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTS 1695
             L ++   PED+  YTC A N  G A TS    V   + +                    
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVV-------------------- 3334

Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
                 S   E+    P    P++D   +E Q A F+ R   V    L+V W      I+ 
Sbjct: 3335 -----SPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 3386

Query: 1756 SN--RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL---QL 1810
            S   R+T   D   + +   Y  PED GTYT  A N +G+  +++ L +++  S+   ++
Sbjct: 3387 SRFFRMTQFEDTYQLEIAEAY--PEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3444

Query: 1811 ESQHESALQKI---QQLEDSSR-----YQRREDVEVAVNQAPRFITQLNGPT-------- 1854
            E + E  ++++    + E S R     +   ED++     A R+ ++++  +        
Sbjct: 3445 EQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKP 3504

Query: 1855 ----KLS-----EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR--YRTSNDFGF-- 1901
                KL+     EG+   + CR+   P P M   W+ N + + +G R   +  +D     
Sbjct: 3505 SFTQKLTFKYVLEGEPVVFTCRLIACPTPEM--TWFHNNRPIPTGLRRIIKAESDLHHHS 3562

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            ++L+I  V   DSG Y   AIN+ G A S+  L V  K
Sbjct: 3563 SSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 72/298 (24%), Positives = 117/298 (39%), Gaps = 16/298 (5%)

Query: 3513 QGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI---- 3568
            + +  + ++ ++   + GT  +    E   G    +T  A    P E   TP  L+    
Sbjct: 891  KSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLK 950

Query: 3569 ---LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
               + E  S   EC +      S  V W+     + +    +     G   L I   +  
Sbjct: 951  NVTVIEGESVTLECHISGY--PSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 1008

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ-LPSHFKSGTESIQKLEETLHKREE 3684
            D+G +TC A N  G  + SC L V+  +    E   +   F +  +   +  + +     
Sbjct: 1009 DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTS 1068

Query: 3685 ITIEDEKPNPPRFTVEIKDNI--DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742
            +T E   P  P     I   +   + EGG V F C+V   G+P   + W  +G P  TG 
Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1126

Query: 3743 R--VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
            R  V      G   L I   +A DAGEYT    NK G  + +A +   A  +++++SQ
Sbjct: 1127 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/282 (24%), Positives = 121/282 (42%), Gaps = 20/282 (7%)

Query: 3667 SGTESIQKLEETLHKREEITIED-------EKPNPPRFTVEIKDNIDVPEGGPVHFDCRV 3719
            +GT   ++  E LH RE    E        E P  P   V    N+ V EG  V  +C +
Sbjct: 907  TGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHI 966

Query: 3720 EPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779
               G P+  + W+       +          G   L I   +A D+G +TC A N+ G+ 
Sbjct: 967  S--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 1024

Query: 3780 TTTAKITCSAKRDIVLESQ-LPQGMSGEKIKELERGRI--SDAPKEE----PIVSTPPKF 3832
            +T+  +      +   E+  + +  + E+ + +E   +  +D    E    P     P F
Sbjct: 1025 STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1084

Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM--GFVSLD 3890
            IT+     + E   V F C+V    +PK  + W ++G  L +G+RY+  Y+   G   L 
Sbjct: 1085 ITKPVVQKLVEGGSVVFGCQVGG--NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLV 1142

Query: 3891 ILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            I   +A+D+GEY     N  GE    A++  +   ++++++Q
Sbjct: 1143 ISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/271 (25%), Positives = 121/271 (44%), Gaps = 16/271 (5%)

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320
            RE +  + A+   P      PP  ++ +++VT ++EG+S   E  +     P   V W+ 
Sbjct: 922  REAKVTETARVPAPVEIPVTPPTLVSGLKNVT-VIEGESVTLECHISGYPSPT--VTWYR 978

Query: 3321 NGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
               ++     ++     GI  L I   + E+SG + C A N+ G  ST   L     E  
Sbjct: 979  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 1038

Query: 3381 ILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKG-----KAPVF-TVPLSNIENLRE 3434
              ++      +   E+ + +E   V   DTS+ EE+       AP F T P+  ++ L E
Sbjct: 1039 EKETTAVT-EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVE 1095

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSGE 3492
            G +  F  ++     P+  V W  +G  L  G R++   +   G   L IS T+ +D+GE
Sbjct: 1096 GGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1153

Query: 3493 YLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            Y     N +GE   +AS+  +    ++++SQ
Sbjct: 1154 YTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 16/234 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLS--GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            P   +K  + +L+    A F+ +L+  G+P   V W  +G+ L  +N+  +I    + +L
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1762

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG  T  A N  G   TS  L V+       + Q  +     Q+ E  ER+
Sbjct: 1763 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1822

Query: 384  EISEKALA-----------PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
               E AL            P  V   +   V EG+  RF CRVTG P P+V W++N + I
Sbjct: 1823 -AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLI 1881

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
            R   + +  V   G H L I +    D+G V   A N  G    + +L + ++E
Sbjct: 1882 RK--SKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1933



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 82/271 (30%), Positives = 115/271 (42%), Gaps = 39/271 (14%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P    PL +     EG+ A F+ R++ TD   LKV WY   K +K    FR         
Sbjct: 3345 PAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFRMTQFEDTYQ 3400

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNII---LESQLPKGM-----EGT 3531
            LEI+  YPED G Y   A N  G+  +TA++ ++   +I+   +E ++   M     EG 
Sbjct: 3401 LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGE 3460

Query: 3532 -----------------ID-KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENS 3573
                             ID K  A + Y+  + + +   E   P  FT   +   + E  
Sbjct: 3461 SEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKP-SFTQKLTFKYVLEGE 3519

Query: 3574 SAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR--VKTINDFGF--VILEIGGVYQRDAGL 3629
               F CRLI      M   WFHN +P+ TG R  +K  +D       LEI  V  RD+G 
Sbjct: 3520 PVVFTCRLIACPTPEMT--WFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGS 3577

Query: 3630 YTCKATNRHG--EATVSCKLQVKGRQGIILE 3658
            Y   A N  G  E+T S  +  KG+    LE
Sbjct: 3578 YRLLAINSEGSAESTASLLVIQKGQDEKYLE 3608



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 97/399 (24%), Positives = 165/399 (41%), Gaps = 52/399 (13%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            KK +     E+    FEV    + +P +KW+ ++  IK S   ++ +      L+++ + 
Sbjct: 2799 KKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNIS 2857

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
              D+  + AV     G  +C A L VE               T T +N+ V   +    +
Sbjct: 2858 PSDAGEYTAVV----GQLECKAKLFVETLH-----------ITKTMKNIEVPETKTASFE 2902

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +V+    +   WLKNG +++   + KI+ +   + L+I+    +DS +Y  V     G 
Sbjct: 2903 CEVSHFN-VPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGN 2957

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V+                 P  I   LKD    E   I F   +  + + + 
Sbjct: 2958 DQVSATLTVT-----------------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SY 2999

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W K    IK +   QM      ++L I      D  DY  V    AG+ T  A L V  
Sbjct: 3000 KWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFV----AGKATSTATLYV-- 3053

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
              +A ++     ++DI V E + A F+ ++ S+   T+QW+++   +  T   ++  E  
Sbjct: 3054 --EARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               LLI +T   D G +T     A G V T AKL V+ +
Sbjct: 3111 VHRLLIPSTRMSDAGKYT---VVAGGNVST-AKLFVEGR 3145



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 32/287 (11%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            K+ W+K  Q ++ G + + +HD     L +I+   ED+ +YTC A N  G    S  L+ 
Sbjct: 3269 KISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3328

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
                ++V   Q                        E+    P   T L++    EGQ A 
Sbjct: 3329 E-VPEVVSPDQ------------------------EMPVYPPAIITPLQDTVTSEGQPAR 3363

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656
            F+ R   VS   LKV WY  +K +K    F  T       L+I    PED GTYT  A N
Sbjct: 3364 FQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASN 3420

Query: 1657 ALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL--EDTSKYQRHSAQDEVITQAPVFT 1714
            A+G+  ++    + + +SI  E   +     + +L  E  S++     +D       +  
Sbjct: 3421 AVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDH 3480

Query: 1715 MPMKDIRVAE--NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
              M   R A   +  + +     P    KL  +++  G P+  + RL
Sbjct: 3481 KSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRL 3527



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 76/284 (26%), Positives = 117/284 (41%), Gaps = 24/284 (8%)

Query: 1553 EQIQVLEDR-SKYHRTDMVD---EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDAT 1608
            E+ +VL  R +K   T  V    E+    P   + LKNV + EG+    E  +      T
Sbjct: 914  ERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT 973

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
              V WY  +  ++S   F  T   G   L I     EDSG +TC A+N  G   TS    
Sbjct: 974  --VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLA 1031

Query: 1669 VHSKKSIYLES----------QHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVF-TMPM 1717
            V   +    E+          +      R   + DTS  +  +   E    AP F T P+
Sbjct: 1032 VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGE--PAAPYFITKPV 1089

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYVALNMKYV 1775
               ++ E  +  F  ++   G+PK  V W ++GVP+    R    ++   G   L +   
Sbjct: 1090 VQ-KLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMT 1146

Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
              +D+G YT    N+ GE   S++L  ++   L ++SQ E   Q
Sbjct: 1147 FADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQ 1190



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 3/183 (1%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            ++IE+S    AP+  +  Q + V +G    F  RV G+P PE  W+ N  +I        
Sbjct: 2067 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2126

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
               E     L+I +VT  DS  +   A N +GET+    L +++ +Q++   F +    +
Sbjct: 2127 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLIT--FTQELQDV 2183

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +E + +         P  ++ W KDG+ +    + R+H+D     L I     SDA  
Sbjct: 2184 VAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAED 2243

Query: 561  YQC 563
            Y C
Sbjct: 2244 YSC 2246



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 69/247 (27%), Positives = 97/247 (39%), Gaps = 11/247 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P     L N+  + EGE+   E  ++    P   V WY     +++   F+     G   
Sbjct: 943  PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIAR 999

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDK-IAAL 3538
            L I   + EDSG + C A N  G   T+  + VQ       E+        T +K     
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059

Query: 3539 EGYSGTVDTLTPE-AESGNP--PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
                 T  +LT E A  G P  P F T P    L E  S  F C++    +    V W  
Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKK 1117

Query: 3596 NGKPLLTGSRVKTI--NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G PL TG R K       G   L I   +  DAG YT    N+HGE + S  L  +   
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1177

Query: 3654 GIILEPQ 3660
             ++++ Q
Sbjct: 1178 ELLMKSQ 1184



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 37/91 (40%), Positives = 51/91 (56%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP ++  LK+  V EG+++   C I G P PTV WY+ D  I+ S  FQ++  +    L 
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            I EAF ED G + C A N AG V+ +  L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 65/233 (27%), Positives = 94/233 (40%), Gaps = 15/233 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
            EG+    E  +   G PS    WY    +++    F+ T   G   L I    A D+G +
Sbjct: 956  EGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013

Query: 2582 MCKAINRAGXXXXX------XXXXXXXXXXIIDQAMRPESWEQIQLKEAAM--NKVPEMF 2633
             C A+N AG                      + +    E    ++ ++  M    + E  
Sbjct: 1014 TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1073

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
               G   AP F T      KLVEG  V    QV     P+  + W K+GV LTTG R K 
Sbjct: 1074 AGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKV 1130

Query: 2694 TFD--FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
            +++   G   L I+    DD+G YT    N  GE  ++AS+  E  + LL +S
Sbjct: 1131 SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1183



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 64/231 (27%), Positives = 101/231 (43%), Gaps = 31/231 (13%)

Query: 255  EIDRS-LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE 313
            E D S L  +  P    KP + K  EG  A+F +++ G P P   WF +GQ+++N   H+
Sbjct: 1445 ETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK 1504

Query: 314  IITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYIT 372
            ++   + T +L +     SDSG +T++A+N  G    S  L VE+  E  V+    + + 
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA-VEHQVKPMFVEKLK 1563

Query: 373  DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
            +   +E   R+E+  +A                          TG P P++ W  N   I
Sbjct: 1564 NVNIKE-GSRLEMKVRA--------------------------TGNPNPDIVWLKNSDII 1596

Query: 433  RDDYNHKILV-NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
                  KI +    G  AL I +    DS   T  A NK+G    +C++NV
Sbjct: 1597 VPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 86/373 (23%), Positives = 137/373 (36%), Gaps = 34/373 (9%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            PQ ++  Q   V  GK  RF   ++GRP P+++W+  ++ +   +  K L ++   + L+
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL-HDGQEYTLL 3297

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNV-----IEKEQ---VVAPKFVERFSTLNVR 503
            +      D+ V TC A+N  G       L+V     +  +Q   V  P  +         
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3357

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            EG+P     R  GT   +++W      I P+   R+        L+I  A   D   Y  
Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3416

Query: 564  TAQNVAG---STAT------RARLYXXXXXXXXXXQKRL-------HLPRPTKVXXXXXX 607
             A N  G   STA        + L+           K L       H  R T+       
Sbjct: 3417 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSE 3476

Query: 608  XXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPT 667
                       +R    I        Y  P F   L     +EG  + F  R+  +  PT
Sbjct: 3477 DIDHKSMA--AKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRL--IACPT 3532

Query: 668  MKIEWLKNGQSIEASSR----FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
             ++ W  N + I    R      S       SL++  +  +DSG Y   A+++ G AE+ 
Sbjct: 3533 PEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAEST 3592

Query: 724  AVLHVTPRATIER 736
            A L V  +   E+
Sbjct: 3593 ASLLVIQKGQDEK 3605



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 83/363 (22%), Positives = 147/363 (40%), Gaps = 56/363 (15%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI W+K    L+TG + K   D    TL +     +D+ +YTC+A N  G A ++AS
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            + +E     + E + PD    +                       I+ L + V  EG   
Sbjct: 3326 LSVE-----VPEVVSPDQEMPV------------------YPPAIITPLQDTVTSEGQPA 3362

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851
             F+C V  +    LK+ W+  +K +     ++ T       L+I   Y ED G YT  A+
Sbjct: 3363 RFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVAS 3419

Query: 2852 NSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGL-EAVEQAEEARLAKGRRPSVPDTE--- 2907
            N+ G  +++ +L     ++I  +    + +  + E   + E     +  R +  D+E   
Sbjct: 3420 NAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDID 3479

Query: 2908 --------YPK--------PEWIIPIAAE----HQLVEGQVLHLEGQVEPKNDPDLKIEW 2947
                    Y          PE+  P   +      ++EG+ +    ++     P++   W
Sbjct: 3480 HKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEM--TW 3537

Query: 2948 YFNGKVLEQGSR--FKLTSDFGF--VTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYC 3003
            + N + +  G R   K  SD      +L++  V +RDSG Y   A N  G A +++++  
Sbjct: 3538 FHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597

Query: 3004 TSK 3006
              K
Sbjct: 3598 IQK 3600



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 64/250 (25%), Positives = 108/250 (43%), Gaps = 36/250 (14%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W+   Q +  G + +  HD     L ++  + ED+  Y C+A N  G A  + +
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325

Query: 2199 LKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            L V     +  D + P                        + PP  +T L+ T    EG+
Sbjct: 3326 LSVEVPEVVSPDQEMP------------------------VYPPAIITPLQDTV-TSEGQ 3360

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT-FDFGYVSLDIQHCVPEDAGEYSV 2317
             A F+C+V      +L++ +Y   K ++ +  F +T F+  Y  L+I    PED G Y+ 
Sbjct: 3361 PARFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTY-QLEIAEAYPEDEGTYTF 3416

Query: 2318 KAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
             A NA+G  +S  ++++ A  SI+ E      +E+  E+E  E F   E        R  
Sbjct: 3417 VASNAVGQVSSTANLSLEAPESILHER-----IEQEIEMEMKELFSEGESEHSERDTRDA 3471

Query: 2378 FTQPLQNIDN 2387
            F+   ++ID+
Sbjct: 3472 FSDS-EDIDH 3480



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 68/248 (27%), Positives = 105/248 (42%), Gaps = 17/248 (6%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ +T  P  +  LK    ++EG+S   E  +      T+T  WY    QI S+   Q  
Sbjct: 937  EIPVTP-PTLVSGLKNVT-VIEGESVTLECHISGYPSPTVT--WYREDYQIESSIDFQIT 992

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID---TSSIHRGLYE 1152
               G   L I    AEDSG +T  A N AG    S  + V+     +   T+   +   E
Sbjct: 993  FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTE 1052

Query: 1153 KTRHIEESKFV--EPMYQIEEISKSKPVFVQPLSNP--PPVSEGKNIHLECRLEPMGDPT 1208
            + R +E    V  +     E+    +P     ++ P    + EG ++   C++   G+P 
Sbjct: 1053 EKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPK 1110

Query: 1209 MRVEWFHNGRSVTVGSRFKTYYD--FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
              V W  +G  +T G R+K  Y+   G   L I    + D GEYT+   N  G   TSA 
Sbjct: 1111 PHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG--ETSAS 1168

Query: 1267 VRVIERSD 1274
              ++E +D
Sbjct: 1169 ASLLEEAD 1176



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 75/321 (23%), Positives = 126/321 (39%), Gaps = 27/321 (8%)

Query: 240  ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
            + +   G S + +   ++     V P    +K +N  ++EG+  + +V+ +GNP P + W
Sbjct: 1531 VAQNRAGRSSISVILTVEAVEHQVKP-MFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1589

Query: 300  FKNGQRLINSN--KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE- 356
             KN   ++     K  I  T     L++ +T   DS  YT  A N  G   T   + VE 
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649

Query: 357  ------------SPTESY------VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
                         P  +Y        +    ++   Q++  E  +   EK   P F K  
Sbjct: 1650 EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKL 1709

Query: 399  QDRDVTEGKMTRFDCRVT--GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
                +       F+CR+T  G P   V W ++D +  +  N   ++NE G  +L      
Sbjct: 1710 TSLRLKRFGPAHFECRLTPIGDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLDYGVAY 1768

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE--RFSTLNVREGEPVVLNARA 514
              DSG++TC A NK G       L V +++ +V    +   R     + E E +      
Sbjct: 1769 SRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGAL 1828

Query: 515  VGTPTPRITWQKDGVPIIPNP 535
             G  T +   QK  + + P P
Sbjct: 1829 TGVTTDQKEKQKPDIVLYPEP 1849



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 75/317 (23%), Positives = 135/317 (42%), Gaps = 23/317 (7%)

Query: 2041 YAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPI 2100
            + +A+   TY  +A   V + V  S      +   + + L   R  K+ E  +   P P+
Sbjct: 881  FPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERF-EVL-HGREAKVTETARV--PAPV 936

Query: 2101 EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT 2160
            E   P   P  ++ L ++  + EG+    EC +     P  T+ W+    +I +   ++ 
Sbjct: 937  EI--PVTPPTLVSGLKNVTVI-EGESVTLECHISGYPSP--TVTWYREDYQIESSIDFQI 991

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT---QHPNGL 2217
            T   G   L I   +AEDSG + C A N+ G    +C L V        +T         
Sbjct: 992  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTT 1051

Query: 2218 EKIRQLEAQG-HSTRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQVEPVHD 2271
            E+ R +E++    T   + E +  P     P F+T+      + EG +  F CQV    +
Sbjct: 1052 EEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GN 1108

Query: 2272 PNLRIEFYHNGKALQSAARFHITFD--FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSA 2329
            P   + +  +G  L +  R+ ++++   G   L I     +DAGEY++   N  G  +++
Sbjct: 1109 PKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1168

Query: 2330 ISMTVTAKGSIISESQR 2346
             S+   A   ++ +SQ+
Sbjct: 1169 ASLLEEADYELLMKSQQ 1185



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 7/195 (3%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  V+ +++ T ++E E+   EC ++  G P+  V W+     +     F   +  G  
Sbjct: 942  PPTLVSGLKNVT-VIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIA 998

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
             +     + EDSG + C A N  G   T   +          ++       + E+ R +E
Sbjct: 999  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1058

Query: 4092 ASWQVTPEQVVEESKAR----CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
            +   V  +  + E +A       P F++ P    + EG    F C+V G+PKP V W  +
Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1118

Query: 4148 GNTIVNGSRYKLTYD 4162
            G  +  G RYK++Y+
Sbjct: 1119 GVPLTTGYRYKVSYN 1133



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 93/390 (23%), Positives = 156/390 (40%), Gaps = 65/390 (16%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P  +Q L  P  V  GK     C +   G P  ++ W+   + ++ G + K  +D     
Sbjct: 3239 PQVLQELQ-PVTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L +I A   D   YT  A N  G A TSA + V E  ++V+  Q                
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEMP------------- 3341

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
                       +  P     L +  T EG     +CR   V    ++V W+   K IK  
Sbjct: 3342 -----------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPS 3387

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI---LESQ 1413
              FR     D   L++   YPED G YT  A+N +G+  ++  L + A + ++   +E +
Sbjct: 3388 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447

Query: 1414 HPSGLEKI------QYLEDTSR--YKKTDIIDESVTIKPRFVTRPKSIEN---------- 1455
                ++++      ++ E  +R  +  ++ ID       R+ +R  S  +          
Sbjct: 3448 IEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFT 3507

Query: 1456 -------VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR--FRPIHDFGY--VAL 1504
                   V+EG+ V F C+L  +     ++ WF N +P+  G R   +   D  +   +L
Sbjct: 3508 QKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSL 3565

Query: 1505 DIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            +I  +   DSG Y   A+N  G+ E +  L
Sbjct: 3566 EIKRVQDRDSGSYRLLAINSEGSAESTASL 3595



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 77/331 (23%), Positives = 137/331 (41%), Gaps = 23/331 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I   P   ++ EG  A+F+ +++G P+P+V W+ NGQ +  S +  +     H  L +
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHY-LDI 1899

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-----SYVQDQRSQYITDTQ---QR 377
             + +  D+G   + AENP G I     L ++   +         + R ++        Q 
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQF 1959

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKM--------TRFDCRVTGRPYPEVTWFIND 429
            E ++     +     + VK+ +   +T  K+        ++F  R T   Y E    +  
Sbjct: 1960 EVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR-TEEGYYEAITAVEL 2018

Query: 430  RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQV 488
            +  + D +++ L+ ++ +  L  T   L++          K     F  + + IE    +
Sbjct: 2019 KSRKKDESYEELLRKTKDELLHWTK-ELTEEEKKALAEEGKITIPTF--KPDKIELSPSM 2075

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH-TDGGAST 547
             APK  ER  +  V +G       R VG P P   W K+GV I  +  +  +  +     
Sbjct: 2076 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135

Query: 548  LDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            L I    A D+A     A N+AG T++ A L
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFL 2166



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 117/499 (23%), Positives = 194/499 (38%), Gaps = 71/499 (14%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PPQ +  L+ VT   G    F   I   G P  KI W K  Q +    +   +      +
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L ++    +D+  YTC A +  GVA T A L V          + PE +   Q++  Y  
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQEMPVYP- 3344

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                          P  I PLQD     EG+ A F+ +   VS   ++V WY   + I  
Sbjct: 3345 --------------PAIITPLQDT-VTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 3386

Query: 816  SS--RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV----- 868
            S   R+T  F   Y  L I     ED G+YT  A N +G+  STA++ + A  ++     
Sbjct: 3387 SRFFRMTQ-FEDTY-QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3444

Query: 869  -------TADLGIPEQRRYIEKTXXXXXX-------XXXXXXXXXXXVPESTQKPE-FKT 913
                     +L    +  + E+                         +  ++  PE FK 
Sbjct: 3445 EQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKP 3504

Query: 914  PIKDQISIK---EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR----ITTFFNFGY 966
                +++ K   EG    F  RL  I   T  + W  + RP+    R      +  +   
Sbjct: 3505 SFTQKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHS 3562

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYL-ED 1025
             +L IK V   D+G Y   A N+ G A ++A+L ++ K     + ++   L++ +   E+
Sbjct: 3563 SSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQ---DEKYLEFLKRAERTHEN 3619

Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQ 1085
                 +R E+ +K+    RF G      + VE +        +  S    T ++ ++ + 
Sbjct: 3620 VEALVERGEDRIKVDL--RFTGSPFNKKQDVEQKGMMRTIHFKTMSSAKKT-DYMYDEEY 3676

Query: 1086 ITSANRIQTYHDFGYVALD 1104
            + S + I+ + + G   LD
Sbjct: 3677 LESKSDIRGWLNVGESFLD 3695



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 70/265 (26%), Positives = 116/265 (43%), Gaps = 42/265 (15%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV PP I    +++   EG  A+FQ ++SG    +V+W+   +++  S    +    +  
Sbjct: 3341 PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3399

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYI---------- 371
             L +      D G YT +A N  G + ++  L++E+P ES + ++  Q I          
Sbjct: 3400 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP-ESILHERIEQEIEMEMKELFSE 3458

Query: 372  --TDTQQRETEERI----EISEKALA--------------PQFVKVCQDRDVT-----EG 406
              ++  +R+T +      +I  K++A              P++ K    + +T     EG
Sbjct: 3459 GESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEG 3518

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH----ALMITNVTLSDSGV 462
            +   F CR+   P PE+TWF N+R I      +I+  ES  H    +L I  V   DSG 
Sbjct: 3519 EPVVFTCRLIACPTPEMTWFHNNRPIPTGL-RRIIKAESDLHHHSSSLEIKRVQDRDSGS 3577

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQ 487
               +A N  G       L VI+K Q
Sbjct: 3578 YRLLAINSEGSAESTASLLVIQKGQ 3602



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 59/243 (24%), Positives = 98/243 (40%), Gaps = 9/243 (3%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +S L N+   EG+++  EC++     PT  + W+  +  + S   ++ T       L I 
Sbjct: 946  VSGLKNVTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIR 1003

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEA---VEQAEEA 2893
              + EDSG +TC A N  G+ +TS  L     +    +T     K   E    VE  +  
Sbjct: 1004 EAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVV 1063

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
                           P   + I      +LVEG  +    QV    +P   + W  +G  
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVP 1121

Query: 2954 LEQGSRFKLT--SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011
            L  G R+K++     G   L +   +  D+G YT    NK GE   S+++   +   L+ 
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1181

Query: 3012 RTQ 3014
            ++Q
Sbjct: 1182 KSQ 1184



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 106/509 (20%), Positives = 190/509 (37%), Gaps = 60/509 (11%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            ++ +W  NG +I S ++ Q        +L+I +V   D+  YT VA  A   A L     
Sbjct: 2997 ISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEAR 3056

Query: 1135 -VETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGK 1193
             +E R  I    +     EK R + E +  EP   ++ +   + +    +++   + + K
Sbjct: 3057 HIEFRKHIKDIKV----LEKKRAMFECEVSEPDITVQWMKDDQEL---QITDRIKIQKEK 3109

Query: 1194 NIHL----ECRLEPMGDPTM-------RVEWFHNGRSVTVGSRFKTYYDFGFVALDI--- 1239
             +H       R+   G  T+         + F  GR V + S  K           +   
Sbjct: 3110 YVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFE 3169

Query: 1240 IHATSADTGEYT--VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARR 1297
            ++    D   Y   +     +   H   + R I R   +++T+   A E   +   A R 
Sbjct: 3170 VNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM-FISETRQSDAGEYTFV---AGRN 3225

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
               V   +   + PQ  + L  +    G      C +   G    ++ W+   + + TG 
Sbjct: 3226 RSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGF 3283

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSG 1417
            + +  ++     L L+  +PED+ VYTC+A N  G A TS +L V   + +  + + P  
Sbjct: 3284 KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP-- 3341

Query: 1418 LEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK 1477
                                    + P  +  P       EGQ   F+C+   V+ ++LK
Sbjct: 3342 ------------------------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLK 3374

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            V W+   + +     FR         L+I +   ED G YT  A N VG    +  L+  
Sbjct: 3375 VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3434

Query: 1538 STTDIVRS-TQNEAGLEQIQVLEDRSKYH 1565
            +   I+    + E  +E  ++  +    H
Sbjct: 3435 APESILHERIEQEIEMEMKELFSEGESEH 3463



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 94/396 (23%), Positives = 156/396 (39%), Gaps = 52/396 (13%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            ++   V E  +A  E +     +  +KWY  +  IK     Q     TK  L+I +    
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2510

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D   +  +     G  + + NL VE K +  RG           +++  T  Q V  + +
Sbjct: 2511 DEGPYKLIV----GRVETNCNLSVE-KIKIIRG----------LRDLTCTETQNVVFEVE 2555

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            ++ +  IDV W    K+++P  + KI      Y L +L     D GKY       AGE  
Sbjct: 2556 LSHSG-IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFY----AGENM 2610

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               +  V                 A   I +PL D+ VAE Q   F C+ V  P    +W
Sbjct: 2611 TSGKLTV-----------------AGGAISKPLTDQTVAESQEAVFECE-VANPDSKGEW 2652

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  K +  +   +      +  L I+    +D G+Y    Y  A   T +AKLKV    
Sbjct: 2653 LRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY---TYKVATSKT-SAKLKV---- 2704

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
              + +     L+++ V E Q A F  ++T      +QW++ G ++     + +  +G   
Sbjct: 2705 --EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIY 2762

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             L I N    D   +  R     G++  SA+L V++
Sbjct: 2763 SLRIKNCAIVDESVYGFR----LGRLGASARLHVET 2794



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 73/288 (25%), Positives = 118/288 (40%), Gaps = 17/288 (5%)

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            T  + T   K  IV    LP       +   E G   +   +  +   PP+FI  I    
Sbjct: 5332 TVPEFTPDHKSMIVSLDVLPFNFVDPNMDSRE-GEDKELKIDLEVFEMPPRFIMPICDFK 5390

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSGHRYRTVYDMGFVSLDILYVYAEDS 3899
            + E+    F+C V     P+  ++WY+    + P   +Y    + G  +L I  V   DS
Sbjct: 5391 IPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDS 5448

Query: 3900 GEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYL 3959
              Y CRAVN  GE   +  ++   + D  +   + +  K + +    E  +K   ++ + 
Sbjct: 5449 ATYRCRAVNCVGEAICRGFLT---MGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFF 5505

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
                 + V  + PPRF+  I    + +      F+C +   G P   V W+ +GK L+  
Sbjct: 5506 E----FQV-VEGPPRFIKGISDCYAPIG-TAAYFQCLVR--GSPRPTVYWYKDGK-LVQG 5556

Query: 4020 NRFT-PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
             RFT      G+  +    +   D GEY C ATN  GM E+ A +  T
Sbjct: 5557 RRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 60/228 (26%), Positives = 99/228 (43%), Gaps = 8/228 (3%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS-RFTSIFRFGYI 694
            PP+FI+P+      E     F+  +  +G PT +++W K    IE  + ++      G  
Sbjct: 5379 PPRFIMPICDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE-TLQYI-QQLED 752
            +L + ++ + DS  Y CRAV+  G A  +  L +         ++  + TL  + ++L  
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496

Query: 753  YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
             S Y       +     P+FI+ + D      G  A+F+  +     PT  V WYKDG+ 
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGISDC-YAPIGTAAYFQCLVRGSPRPT--VYWYKDGKL 5553

Query: 813  ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            +            G+ +L I  L   D G Y   A NK G A S A++
Sbjct: 5554 VQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 5601



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 66/258 (25%), Positives = 108/258 (41%), Gaps = 17/258 (6%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            +++ EG     E  +      T  V W ++   +E+S      F  G   L I+     D
Sbjct: 952  VTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAED 1009

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ---HPGGLEKIQYLEDASRY---SKR 1032
            +G +TC A N  G  +TS  L +   ++   E+         E+ +++E        +  
Sbjct: 1010 SGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSL 1069

Query: 1033 TEEEVKITQK--PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN 1090
            TEE+    +   P F+       K+VEG S  F  +V    +    V W  +G  +T+  
Sbjct: 1070 TEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1126

Query: 1091 RIQTYHD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
            R +  ++   G   L I+   A+D+G YT+V RN  GE   SAS+  E    +   S   
Sbjct: 1127 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQE 1186

Query: 1149 GLYEK--TRHIEESKFVE 1164
             LY+   T  ++E K  E
Sbjct: 1187 MLYQTQVTAFVQEPKVGE 1204



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 63/230 (27%), Positives = 100/230 (43%), Gaps = 9/230 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYV 967
            P F  PI D   I E   A F+  +  IG  T  V+W K+   +E  + +       G  
Sbjct: 5380 PRFIMPICD-FKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK--DIIAESQHPGGLEKIQYLED 1025
             L I++V + D+  Y CRA N +G+A     LT+   +   +IA+         ++ L  
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496

Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQ 1085
             S Y+    E   +   PRF+  +      + G +A+F+  V  +     TV WY +GK 
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLV--RGSPRPTVYWYKDGKL 5553

Query: 1086 ITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +            G+  L I S+   D G Y  VA N +G A+  A++T+
Sbjct: 5554 VQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 109/422 (25%), Positives = 161/422 (38%), Gaps = 72/422 (17%)

Query: 2204 HRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFE 2263
            HR  I +T+  +  E          S  + V  P+  PP+ + EL+  T V  GK A F 
Sbjct: 3203 HRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPE--PPQVLQELQPVT-VQSGKPARF- 3258

Query: 2264 CQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINAL 2323
            C V     P  +I +Y   + L +  +     D    +L +    PEDA  Y+ +A N  
Sbjct: 3259 CAVISGR-PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 3317

Query: 2324 GHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQ 2383
            G  T++ S++V            PE +   +E+        P  P       P    PLQ
Sbjct: 3318 GVATTSASLSVEV----------PEVVSPDQEM--------PVYP-------PAIITPLQ 3352

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            +     EGQ A F CR   V    LKV W+  +K I+ S     T       + I+    
Sbjct: 3353 DTVT-SEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 3408

Query: 2444 EDEGVYMCRASNLLGEXXXXXXXXXXXXXXI---QLETQHPEGMKKI-QKLEQPHERR-- 2497
            EDEG Y   ASN +G+              I   ++E +    MK++  + E  H  R  
Sbjct: 3409 EDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDT 3468

Query: 2498 ------SEEPDRE-------------------FEKPIFTQVLTGPSELWEGQHAHYEARV 2532
                  SE+ D +                   + KP FTQ LT    L EG+   +  R+
Sbjct: 3469 RDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVL-EGEPVVFTCRL 3527

Query: 2533 VPVGDPSLRFEWYINGVELKMGSR--FRTTHDFGF--VTLDINSVVANDAGLYMCKAINR 2588
            +    P +   W+ N   +  G R   +   D      +L+I  V   D+G Y   AIN 
Sbjct: 3528 IACPTPEM--TWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINS 3585

Query: 2589 AG 2590
             G
Sbjct: 3586 EG 3587



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 166/768 (21%), Positives = 292/768 (38%), Gaps = 65/768 (8%)

Query: 3675 LEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
            LEE   ++  + I + +     F   IK N  + EG  V F C++   G P  +I W+ +
Sbjct: 1271 LEEDGEEKMAVDISESEAVESGFDSRIK-NYRILEGMGVTFHCKMS--GYPLPKIAWYKD 1327

Query: 3735 GRPFATGSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
            G+    G R     L D G  +L I  +   D G YT  A+N  G+A  + K+       
Sbjct: 1328 GKRIKHGERYQMDFLQD-GRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAP 1386

Query: 3793 IVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECR 3852
            +   + +P      +I+ L    +S +P         P  ++  +      S G R E  
Sbjct: 1387 LGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEET 1446

Query: 3853 VEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
             E + +   +  +                +D+  V   +   +    G+ I   VND+  
Sbjct: 1447 DESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQI---VNDYTH 1503

Query: 3913 DFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQP 3972
               K  I       +I+    P        + Q  A   + +  V LT +    V+ +  
Sbjct: 1504 ---KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRA--GRSSISVILTVE---AVEHQVK 1555

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLL-HKNRFTPIYDF-GY 4030
            P FV ++++       E ++ E ++   G+PN  + W  N   ++ HK     I    G 
Sbjct: 1556 PMFVEKLKNVNI---KEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE 1612

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT---GKPGIVYDSQLPKHMKSIEKI 4087
             A+       +DS  Y   A N  G D T+  +       +P       +P+     ++I
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 4088 R--EME-ASWQVTPEQVVE----ESKARCPPVFVSLPDAVTVEEGEWARFCCRVT--GHP 4138
               E+E    +   EQ  E    + + +  P F     ++ ++    A F CR+T  G P
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDP 1732

Query: 4139 KPRVMWLLNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXL 4197
               V WL +G  +   +R ++  + G    D       D+G I                L
Sbjct: 1733 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1792

Query: 4198 KVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGV-IDHRPELKPK 4256
             V     D + +++ +  P  +     QR E ELE+   E  +    GV  D + + KP 
Sbjct: 1793 IV----KDEKSLVEESQLP--EGRKGLQRIE-ELERMAHEGAL---TGVTTDQKEKQKPD 1842

Query: 4257 VIKEPE----TEWQQSVKRKKNEEY-YNKLQELENEQVIKES---RLR-ESTHQYAIPGD 4307
            ++  PE     E + +  R +   Y   K+    N Q+I++S   R+R +  H   I   
Sbjct: 1843 IVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDC 1902

Query: 4308 KVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQ 4367
            K       K  A+  E  ++   ++  Q+ +   +   R P+P        E HV +  +
Sbjct: 1903 KSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPR------PEFHVHEPGK 1956

Query: 4368 TQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK 4415
             Q EV   +++ R + +TET E+  K +  ER+    V      + +K
Sbjct: 1957 LQFEV---QKVDRPVDTTETKEVV-KLKRAERITHEKVPEESEELRSK 2000



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 60/237 (25%), Positives = 91/237 (38%), Gaps = 16/237 (6%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
            EG +   E  ++    PT  V WY++   I +S      F  G   L I    AED+G +
Sbjct: 956  EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013

Query: 844  TVRAVNKLGEAISTASIRVAA------RSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXX 897
            T  AVN+ G   ++  + V         +T   +    E++R++E               
Sbjct: 1014 TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1073

Query: 898  XXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR 957
                 P     P F T    Q  + EGG   F  ++   G+    V W K G P+    R
Sbjct: 1074 AG---PGEPAAPYFITKPVVQ-KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYR 1127

Query: 958  ITTFFN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
                +N   G   L I      DAG YT    N  G+ + SA+L      +++ +SQ
Sbjct: 1128 YKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 67/235 (28%), Positives = 96/235 (40%), Gaps = 16/235 (6%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI--NDFGF 3614
            PP F     D  + ENS A F+C +I +   +  V+W+      +    +K +   + G 
Sbjct: 5379 PPRFIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYM-CIEPDNIKYVISEEKGS 5435

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ--GIILEPQLPSHFKSGTESI 3672
              L+I  V   D+  Y C+A N  GEA     L +   +   +I +    +      E +
Sbjct: 5436 HTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELV 5495

Query: 3673 QKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWF 3732
             K   T    E   +E     PPRF   I D    P G   +F C V   G P   + W+
Sbjct: 5496 LKSNYTDSFFEFQVVE----GPPRFIKGISDCY-APIGTAAYFQCLVR--GSPRPTVYWY 5548

Query: 3733 HNGRPFATGSRVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             +G+    G R        GF  L I  +   D GEY C ATNK G A + A +T
Sbjct: 5549 KDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALT 5602



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 43/147 (29%), Positives = 73/147 (49%), Gaps = 12/147 (8%)

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQK-P 272
            D  S + F+ +  E + + +    +S   R+V  SD  I+ E         PPK+ Q+ P
Sbjct: 4117 DKESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSD--ITNE---------PPKMLQEMP 4165

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
            ++++ +EG     +  +SG P+P VTWF+NG  L  + K +    +    L +++    D
Sbjct: 4166 KHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQD 4225

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPT 359
            SG Y  +AEN +G + +   L VE  T
Sbjct: 4226 SGKYKCVAENNSGAVESVSDLTVEPVT 4252



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 10/203 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVY 3101
            T + P FT   + +V + EG  A +EA +  +G     + WF +G+ I  S    ++  +
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
            + G   L I      +SG YS +ATN  GQA  + +L  + K++   P F   +Q++  +
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMT-V 115

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            + G     +  V  +  P +K  +Y +G  ++ S   +   +     L IA     DSG 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGT 173

Query: 3222 YVCRAYNKYGEDFTRATINCYGK 3244
            Y   A N  G   + A +   G+
Sbjct: 174  YSVNATNSVGRATSTAELLVQGE 196



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 35/116 (30%), Positives = 55/116 (47%)

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            V +    +VT  A++             ++ L+++ V EG+    +  I+    PT+ W 
Sbjct: 918  VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 977

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            RE   I  + DFQ+  +   A L+I   + ED+G FTC A   AG V TS  L V+
Sbjct: 978  REDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 89/331 (26%), Positives = 136/331 (41%), Gaps = 32/331 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI---EASHRIRTVYAF-----GMVV-LEI 3110
            + E  + H  +S  P+  Q +V+E   + K +   E   +I TV  F      M+V L++
Sbjct: 5291 VMEFDLEHTTSSRTPS-PQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPDHKSMIVSLDV 5349

Query: 3111 LGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            L     D    S    +K    E+ + LE  +      PRF   I + + + +   A F+
Sbjct: 5350 LPFNFVDPNMDSREGEDK----ELKIDLEVFE----MPPRFIMPICDFK-IPENSDAVFK 5400

Query: 3171 CTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNK 3229
            C+V+ +  P++K  WY     +        +S+  G   L I      DS  Y CRA N 
Sbjct: 5401 CSVIGIPTPEVK--WYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNC 5458

Query: 3230 YGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE----PPKFI 3285
             GE   R  +   G   ++    +   +     +E L      T S    +    PP+FI
Sbjct: 5459 VGEAICRGFLTM-GDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFI 5517

Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD-FGIVILDI 3344
              I D    + G +A+F+  LV    P   V W+ +GK L  G R+       G   L I
Sbjct: 5518 KGISDCYAPI-GTAAYFQC-LVR-GSPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFI 5573

Query: 3345 LYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
                + + GEY CVATNK G   + A L  T
Sbjct: 5574 TSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 78/342 (22%), Positives = 121/342 (35%), Gaps = 19/342 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN-K 470
            + RV   P P   +   D    D Y  +  V       + IT  T+ +        R  K
Sbjct: 868  ETRVRAEPTPLPQFPFADTP--DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAK 925

Query: 471  SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530
              ETA   R+    +  V  P  V     + V EGE V L     G P+P +TW ++   
Sbjct: 926  VTETA---RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQ 982

Query: 531  IIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQ 590
            I  + + +I    G + L I  A A D+  + C+A N AG+ +T   L           +
Sbjct: 983  IESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL---AVQVSEEFE 1039

Query: 591  KRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAME 650
            K                       +           PGE       P FI        +E
Sbjct: 1040 KETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEP----AAPYFITKPVVQKLVE 1095

Query: 651  GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--RFGYISLDMLSLNIQDSGE 708
            GG + F  ++   G+P   + W K+G  +    R+   +  + G   L +      D+GE
Sbjct: 1096 GGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1153

Query: 709  YTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQL 750
            YT    +  G  ET A   +   A  E   +  + + Y  Q+
Sbjct: 1154 YTIVVRNKHG--ETSASASLLEEADYELLMKSQQEMLYQTQV 1193



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 92/397 (23%), Positives = 155/397 (39%), Gaps = 53/397 (13%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            +K +    V E ++A FE E    P    +W R+   +  + + +  +   K  LII   
Sbjct: 2623 SKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAAT 2681

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             ++D   +      +  T+K SA L VE  +              T +N+ VT  Q    
Sbjct: 2682 KLDDIGEYTY----KVATSKTSAKLKVEAVK-----------IKKTLKNLTVTETQDAVF 2726

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              ++T      V W+KNG  ++ + +  I  +   Y+L I      D   Y         
Sbjct: 2727 TVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGA 2786

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR   E V                     +II+  KD    E   + F   +    +P 
Sbjct: 2787 SARLHVETV---------------------KIIKKPKDVTALENATVAFEVSVSHDTVP- 2824

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            V+W+     IKPS   ++      + L +    P D G+Y  V     G++   AKL V 
Sbjct: 2825 VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFV- 2879

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
                 + L     +++I V E + A F+ +++    P++ WL+ G  I  +  F+++ +G
Sbjct: 2880 -----ETLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG 2933

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                L+I NT  ED+  +    T   G  + SA L V
Sbjct: 2934 KLHQLIIMNTSTEDSAEY----TFVCGNDQVSATLTV 2966



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 8/161 (4%)

Query: 357  SPTESYVQDQRSQYITDTQQRETEE-RIE--ISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
            S T + V+++R + +   + + TE  R+   +      P  V   ++  V EG+    +C
Sbjct: 905  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
             ++G P P VTW+  D QI    + +I   +SG   LMI      DSG  TC A N++G 
Sbjct: 965  HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023

Query: 474  TAFQCRL--NVIEKEQVVAPKFVERFSTLNVR--EGEPVVL 510
             +  C L   V E+ +       E+F+T   R  E   VV+
Sbjct: 1024 VSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVM 1064



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 133/626 (21%), Positives = 236/626 (37%), Gaps = 88/626 (14%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+ + +++  TV+  +  RF   +  +  PK  I WY+  +LL +G + +         
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPK--ISWYKEEQLLSTGFKCK--------- 3286

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
                  +  D  EY    +  F ED   A  +C+   D         G+  + A   +E 
Sbjct: 3287 ------FLHDGQEYTLLLIEAFPED--AAVYTCEAKNDY--------GVATTSASLSVEV 3330

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
                   EV   + ++       PP  +T +Q  T   E +  +F+C+   V   ++KV 
Sbjct: 3331 P------EVVSPDQEM----PVYPPAIITPLQD-TVTSEGQPARFQCR---VSGTDLKVS 3376

Query: 4009 WFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W+   K +   +RF  +  F     +     YPED G Y   A+N  G   + A +    
Sbjct: 3377 WYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435

Query: 4068 KPGIVYD---SQLPKHMKSIEKIREMEASWQVT------PEQVVEESKAR---------- 4108
               I+++    ++   MK +    E E S + T       E +  +S A           
Sbjct: 3436 PESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISST 3495

Query: 4109 --CPPVFV-SLPDAVT---VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR--YKLT 4160
               P  F  S    +T   V EGE   F CR+   P P + W  N   I  G R   K  
Sbjct: 3496 SSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAE 3555

Query: 4161 YDGMYH---FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDD--YRGVLKNAPR 4215
             D  +H    +I + +  D+G   ++             L VI +  D  Y   LK A R
Sbjct: 3556 SDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAER 3615

Query: 4216 PWYDETTQYQRTETELE-------KTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQS 4268
               +     +R E  ++         F ++Q ++++G++           K+ +  + + 
Sbjct: 3616 THENVEALVERGEDRIKVDLRFTGSPFNKKQDVEQKGMMRTIHFKTMSSAKKTDYMYDEE 3675

Query: 4269 VKRKKNE--EYYNKLQE-LENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDN 4325
                K++   + N  +  L+ E  +K  RLRE+  +  +   K++    +  ++ R   +
Sbjct: 3676 YLESKSDIRGWLNVGESFLDKETKVKLQRLREA-RKTLMEKKKLSLLDTSSEISSRTLRS 3734

Query: 4326 LDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITST 4385
                +++   R   K+     + + S    H  E  V        ++  + E     TS 
Sbjct: 3735 EASDKDILFSREDMKIRSMSDLAE-SYKVDHSAESIVQNPHALSNQMDQNIESEELPTSF 3793

Query: 4386 ETTEIEHKAQTQERV-VEGPVKPSKP 4410
            +T   E   QT+ R+  E  VK S P
Sbjct: 3794 QTIVDEEIFQTEIRMSQEALVKESLP 3819



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 63/235 (26%), Positives = 99/235 (42%), Gaps = 15/235 (6%)

Query: 2363 KRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-D 2421
            K  +I   V    P F  P+ +   I E   A F C +I  G PT +V+W++    IE D
Sbjct: 5367 KELKIDLEVFEMPPRFIMPICDF-KIPENSDAVFKCSVI--GIPTPEVKWYKEYMCIEPD 5423

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHP 2481
            + +   + + G  ++ I +V   D   Y CRA N +GE                +  +  
Sbjct: 5424 NIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAK-- 5481

Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIF---TQVLTGPSELWE--GQHAHYEARVVPVG 2536
            +    +  L +    +S   D  FE  +     + + G S+ +   G  A+++  V   G
Sbjct: 5482 KSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLV--RG 5539

Query: 2537 DPSLRFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
             P     WY +G +L  G RF       GF  L I S+V +D G Y C A N++G
Sbjct: 5540 SPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 5593



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 56/232 (24%), Positives = 99/232 (42%), Gaps = 7/232 (3%)

Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGS-RFTETN 1630
            EV    P     + + +I E   A F+  +I +   T +V+WY     ++  + ++  + 
Sbjct: 5374 EVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIP--TPEVKWYKEYMCIEPDNIKYVISE 5431

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG-IAIVHSKKSIYLESQHEGALPRL- 1688
              G   L I +    DS TY CRA+N +GEA+  G + +  S+    +  + +  L  L 
Sbjct: 5432 EKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLM 5491

Query: 1689 NQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748
             +L   S Y     + +V+   P F   + D       AA+F+   +  G P+  V W +
Sbjct: 5492 EELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC--LVRGSPRPTVYWYK 5549

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
            +G  ++           G+  L +  +   D G Y C A N+ G A + + L
Sbjct: 5550 DGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 5601



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 82/307 (26%), Positives = 134/307 (43%), Gaps = 46/307 (14%)

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
            ++ K+ E   A F+ ++S  P   V W K+ Q L  +++ +I        L + +T+ SD
Sbjct: 3065 KDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 3123

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
            +G YT++A    G  V++  L VE                D + R  ++ +++ EK  A 
Sbjct: 3124 AGKYTVVA----GGNVSTAKLFVEG--------------RDVRIRSIKKEVQVIEKQRAV 3165

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
               +V +D DV              +   E+ + + +R       HK +V E   H + I
Sbjct: 3166 VEFEVNED-DVDAHWY---------KDGIEINFQVQER-------HKYVV-ERRIHRMFI 3207

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +    SD+G  T VA RN+S  T +   +N  E  QV+     +    + V+ G+P    
Sbjct: 3208 SETRQSDAGEYTFVAGRNRSSVTLY---VNAPEPPQVL-----QELQPVTVQSGKPARFC 3259

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            A   G P P+I+W K+   +    + +   DG   TL +  A   DAA Y C A+N  G 
Sbjct: 3260 AVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGV 3319

Query: 572  TATRARL 578
              T A L
Sbjct: 3320 ATTSASL 3326



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 78/271 (28%), Positives = 115/271 (42%), Gaps = 40/271 (14%)

Query: 625  IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
            + P +E  VYPP   I PL+     EG    F+ R   V    +K+ W    + I+  SR
Sbjct: 3334 VSPDQEMPVYPPA-IITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIK-PSR 3388

Query: 685  FTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATG-VAET--------KAVLHVTPRATI 734
            F  + +F     L++     +D G YT  A +A G V+ T        +++LH      I
Sbjct: 3389 FFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEI 3448

Query: 735  ER---------TSQHPE--TLQYIQQLEDYS----KYQHQESIEEQTSQRPQFIRP--LQ 777
            E           S+H E  T       ED        +   S    TS  P++ +P   Q
Sbjct: 3449 EMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQ 3508

Query: 778  DL--GELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI-TASSRI---TSIFNFGYVSLN 831
             L    + EG    F  +L  ++ PT  + W+ + RPI T   RI    S  +    SL 
Sbjct: 3509 KLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLE 3566

Query: 832  IMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            I  ++  D+GSY + A+N  G A STAS+ V
Sbjct: 3567 IKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 60/233 (25%), Positives = 101/233 (43%), Gaps = 22/233 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH-RFKTTYDFGYVA 2036
            P+F  PI + ++ E      + ++  +  PT  V+WY     ++  + ++  + + G   
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYMCIEPDNIKYVISEEKGSHT 5437

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAV-----TTSSVKVDA----KSGLYLDTLDEQRLKK 2087
            L I      D+ TY C+A N VGEA+     T    ++ A    KS + L +L E+ + K
Sbjct: 5438 LKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLK 5497

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                + +   + +E       P F+  ++       G  A+F+C V     P  T+ W+ 
Sbjct: 5498 SNYTDSFFEFQVVEGP-----PRFIKGISDC-YAPIGTAAYFQCLVR--GSPRPTVYWYK 5549

Query: 2148 NGQKIRAGHRYRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
            +G K+  G R+       G+  L I      D G Y C ATNK G A +   L
Sbjct: 5550 DG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 5601



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 13/141 (9%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFF 962
            +TQ P F  P++  + + EG  A FEA +   G     V W +DG+ +  S+   +   F
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            + G   LTI +VT  ++G Y+ +A N  GQAT++A L +       AE+  P  ++++Q 
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK------AETAPPNFVQRLQS 112

Query: 1023 LEDASRYSKRTEEEVKITQKP 1043
            +    R   +   +V++T  P
Sbjct: 113  M--TVRQGSQVRLQVRVTGIP 131



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 99/418 (23%), Positives = 158/418 (37%), Gaps = 67/418 (16%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            +Y   A R        V   + P+ L  L+    +  G+ A F A +  +      + WY
Sbjct: 3217 EYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVT-VQSGKPARFCAVISGRPQ--PKISWY 3273

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
               + +++  + +  HD     L +     ED+ VYT  A+N  G A  SAS++VE    
Sbjct: 3274 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3333

Query: 1141 IDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECR 1200
            +                            +E+    P  + PL +    SEG+    +CR
Sbjct: 3334 VSPD-------------------------QEMPVYPPAIITPLQDTV-TSEGQPARFQCR 3367

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
            +       ++V W+   + +     F+         L+I  A   D G YT  A N +G 
Sbjct: 3368 VS---GTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ 3424

Query: 1261 AHTSAIVRVIERSDIVTDT-QNEQAIEQIQLL-----EDAARRTKQV---REDIT--VMQ 1309
              ++A + +     I+ +  + E  +E  +L      E + R T+      EDI    M 
Sbjct: 3425 VSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMA 3484

Query: 1310 A------------------PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK 1351
            A                  P F++ L     +EG  V   CRL  +   T  + WF N +
Sbjct: 3485 AKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNR 3542

Query: 1352 PIKTGHRFRPAYEFDY----VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            PI TG R     E D      +L++  V   DSG Y   A N  G A ++ +L VI K
Sbjct: 3543 PIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 3/115 (2%)

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
            Q  ST   + + + +PP FV  L+  T V +G     + +V  +  P   ++FY +G  +
Sbjct: 88   QATSTAELLVKAETAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEI 144

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
            QS+  F I+ +    SL I    PED+G YSV A N++G  TS   + V  +  +
Sbjct: 145  QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 2/106 (1%)

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            + PP+     +NV V  G+ V L+  ++G     V W +   +++  I  +I  + G   
Sbjct: 940  VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 999

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
            L+I EA+ +DSG++ C A+N AG       C +++  +++  K  T
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTV--STSCYLAVQVSEEFEKETT 1043



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIF 823
           T+Q P F +PLQ +  L EG  A FEA ++    P   V W++DG+ I+ S+   +   F
Sbjct: 2   TTQAPTFTQPLQSVVVL-EGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           + G   L I  +   ++G Y+++A N  G+A STA + V A +
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 105/508 (20%), Positives = 194/508 (38%), Gaps = 58/508 (11%)

Query: 4306 GDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQ 4365
            G+ +TS  +  +     +   DQT   +++ V +     P      E    GK + +   
Sbjct: 2607 GENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANP--DSKGEWLRDGKHLPLTNN 2664

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
             +++ +    + I       +  E  +K  T +   +  V+  K     K ++   V E 
Sbjct: 2665 IRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVK---IKKTLKNLTVTET 2721

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            + A F VE     +  ++W +    ++++  + I    T   L I+   + D +V+    
Sbjct: 2722 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGF-- 2779

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
              R G    SA L VE  +      I  P      +N  V     V  DT       + V
Sbjct: 2780 --RLGRLGASARLHVETVKI-----IKKPKDVTALENATVAFEVSVSHDT-------VPV 2825

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W     +++P  +++++ E   + L++    P D+G+Y  V     G+  C A+  V  
Sbjct: 2826 KWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVE- 2880

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                               I + +K+  V E +   F C++    +P++ W K    I+ 
Sbjct: 2881 ----------------TLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEM 2923

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+ F++      + L I     ED  +Y  V     G   V+A L VT       +   +
Sbjct: 2924 SEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGNDQVSATLTVTP------IMITS 2973

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             L+DI   E     F+  +  +   + +WL+ G  I  T   QM  +     L I N + 
Sbjct: 2974 MLKDINAEEKDTITFEVTVNYE-GISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHF 3032

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             D   +    T  AG+  ++A L V+++
Sbjct: 3033 GDAADY----TFVAGKATSTATLYVEAR 3056



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 4722 PALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMIHEGNNAVL 4778
            P  T PL+ +VV EG  A F+  I+    P + W R+G +I  +  P  Q+      A L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             I    + ++G ++ +AT  +GQ  ++A+L+VK++T
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 60/232 (25%), Positives = 96/232 (41%), Gaps = 12/232 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH-RYRTTHDFGYV 2167
            P F+  +   + + E   A F+C V  I  P   + W+     I   + +Y  + + G  
Sbjct: 5380 PRFIMPICDFK-IPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR--NIILDTQHPNGLEKIRQLEA 2225
             L I      DS TY C+A N +GEA+    L +       +I           + +L  
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496

Query: 2226 QGHSTRIEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKA 2284
            + + T    E   +  PPRF+  +    +   G  A+F+C V     P   + +Y +GK 
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGI-SDCYAPIGTAAYFQCLVR--GSPRPTVYWYKDGKL 5553

Query: 2285 LQSAARFHI-TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
            +Q   RF +     G+ +L I   V  D GEY   A N  G   S  ++T+T
Sbjct: 5554 VQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++  V +G  V L+  +T +  PT  V++Y +G  +Q    F+ + +    +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             I  AY ED+GTY   ATN+VG A +T+ + V  +
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765
            TQAP FT P++ + V E   A FEA +   G P   V W R+G  I  S        F  
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSD 60

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            G   L +  V   +SG Y+ +A N  G+A +++ L V+++ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 91/406 (22%), Positives = 159/406 (39%), Gaps = 71/406 (17%)

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            ++T    +  PP+       + +     A F C +I       ++ W+   + L TG + 
Sbjct: 3228 SVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQP-KISWYKEEQLLSTGFKC 3285

Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            K ++D     L +   +  DA +YTC+A N +G AT S  L V+  + +  + ++P +  
Sbjct: 3286 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVY-- 3343

Query: 3667 SGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT 3726
                 I  L++T      +T E +   P RF                   CR   V    
Sbjct: 3344 -PPAIITPLQDT------VTSEGQ---PARF------------------QCR---VSGTD 3372

Query: 3727 MRIDWFHNGRPFATGSRVHTLNDF-GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +++ W+   +     SR   +  F     L+I   Y  D G YT  A+N  G  ++TA +
Sbjct: 3373 LKVSWYSKDKKIKP-SRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3431

Query: 3786 TCSAKRDIV---LESQLPQGM-------SGEKIKELERGRISDAPKEEPIVSTPPKFITQ 3835
            +  A   I+   +E ++   M         E  +   R   SD+   +       ++ ++
Sbjct: 3432 SLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASR 3491

Query: 3836 IKSHT------------------VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
            I S +                  V E E V F CR+     P++   W+ N + +P+G R
Sbjct: 3492 ISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEM--TWFHNNRPIPTGLR 3549

Query: 3878 --YRTVYDMGF--VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               +   D+     SL+I  V   DSG Y   A+N  G   + A++
Sbjct: 3550 RIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASL 3595



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 51/238 (21%), Positives = 105/238 (44%), Gaps = 10/238 (4%)

Query: 2224 EAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGK 2283
            E +    +I++E  ++ PPRF+  +     + E   A F+C V  +  P   +++Y    
Sbjct: 5363 EGEDKELKIDLEVFEM-PPRFIMPICDFK-IPENSDAVFKCSVIGIPTPE--VKWYKEYM 5418

Query: 2284 ALQ-SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAISMTVTAKGSI 2340
             ++    ++ I+ + G  +L I++    D+  Y  +A+N +G   C   ++M  +   ++
Sbjct: 5419 CIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAV 5478

Query: 2341 ISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRL 2400
            I++  +      + EL     +        V    P F + + +      G  A+F C  
Sbjct: 5479 IAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDC-YAPIGTAAYFQC-- 5535

Query: 2401 IPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            +  G P   V W+++ KL++      +    G+ ++ I+ +   DEG Y C A+N  G
Sbjct: 5536 LVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 5593



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 62/232 (26%), Positives = 102/232 (43%), Gaps = 16/232 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYVSLD 2834
            FI  + +    E  +  F+C+V     PT +++W+     + P   +Y  + +    +L 
Sbjct: 5382 FIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I +    DS  Y C+A N  G A   G L   GD  I F     + K  L ++   EE  
Sbjct: 5440 IRNVCLSDSATYRCRAVNCVGEAICRGFLTM-GDSEI-FAVIAKKSKVTLSSL--MEELV 5495

Query: 2895 LAKGRRPSVPDTEYPK--PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            L      S  + +  +  P +I  I+  +  + G   + +  V  +  P   + WY +GK
Sbjct: 5496 LKSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLV--RGSPRPTVYWYKDGK 5552

Query: 2953 VLEQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRG--EAFTSSTV 3001
            ++ QG RF +  S  GF  L +  + + D G Y C A NK G  E+F + T+
Sbjct: 5553 LV-QGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 4/137 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH--EIITTHNHTTL 323
           P   Q  ++  + EG+ A F+  +SG P P V+WF++GQ +  S     +I  +     L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +    K++SG Y+L A N +G   ++  L V++ T      QR Q +T  Q   ++ R+
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQ--GSQVRL 123

Query: 384 EISEKALAPQFVKVCQD 400
           ++    +    VK  +D
Sbjct: 124 QVRVTGIPTPVVKFYRD 140



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 30/98 (30%), Positives = 55/98 (56%), Gaps = 2/98 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L ++   +G+ V L+ R+   G  T  V+++ +G  I++   F+ + E D  +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
             +   YPEDSG Y+  ATN +G A ++  L V  ++++
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 12/160 (7%)

Query: 1792 GEAVTSSTL------FVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQA 1843
            G+ +++STL      F   +A L + +  +  S    ++    S +     ++ V    A
Sbjct: 43   GQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102

Query: 1844 P-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            P  F+ +L   T + +G     + R+   P P   V++Y +G  +QS   ++ S +    
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +L I   Y EDSG Y+  A N++G+A S+  L VQ +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 58/228 (25%), Positives = 97/228 (42%), Gaps = 14/228 (6%)

Query: 352  YLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRF 411
            +L++ +   S  +D     + D   + T + I   E A+  +FVK  QD +V E      
Sbjct: 2230 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIV--EGAVV-EFVKELQDIEVPESYSGEL 2286

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V+     E  W+ ND +++ +  + I  +  G   L + +VT  D G  + V   K 
Sbjct: 2287 ECIVSPENI-EGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFVIDGKK 2344

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
                  C+L +  K + +A   ++  S   V EG+ V L  + V   +    W KDG  +
Sbjct: 2345 TT----CKLKM--KPRPIA--ILQGLSDQKVCEGDIVQLEVK-VSLESVEGVWMKDGQEV 2395

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             P+  + I  D  +  L I      DA  Y  T   +  ST+ R  +Y
Sbjct: 2396 QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2443



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 82/351 (23%), Positives = 132/351 (37%), Gaps = 50/351 (14%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP      ++   ++G  A+F+ ++ G    V SW  K   +     + M   E T    
Sbjct: 3344 PPAIITPLQDTVTSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFEDT--YQ 3400

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I +  P DEG YT  A N  G+   +  +  E                   E++ H+ 
Sbjct: 3401 LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA-----------------PESILHER 3443

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
                    ++     K  ++ G    S  D + D F      ++  +    KRY      
Sbjct: 3444 I------EQEIEMEMKELFSEGESEHSERDTR-DAFSDS--EDIDHKSMAAKRYAS---- 3490

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
            +IS+    S      P   QK     + EG    F  +L   P P +TWF N  R I + 
Sbjct: 3491 RISST--SSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNN-RPIPTG 3547

Query: 311  KHEIITT-----HNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV--ESPTESYV 363
               II       H+ ++L ++  Q  DSG Y LLA N  G   ++  L V  +   E Y+
Sbjct: 3548 LRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYL 3607

Query: 364  Q----DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410
            +     +R+    +      E+RI++  +     F K    +DV +  M R
Sbjct: 3608 EFLKRAERTHENVEALVERGEDRIKVDLRFTGSPFNK---KQDVEQKGMMR 3655



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 61/237 (25%), Positives = 96/237 (40%), Gaps = 14/237 (5%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
            K+  I  E   + PRF+  P     + E     F+C +  +    +K  W+K    +   
Sbjct: 5367 KELKIDLEVFEMPPRFIM-PICDFKIPENSDAVFKCSVIGIPTPEVK--WYKEYMCIEPD 5423

Query: 1491 H-RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR-LTCRSTTDIVRSTQN 1548
            + ++    + G   L I ++   DS  Y CRAVN VG  E  CR       ++I      
Sbjct: 5424 NIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVG--EAICRGFLTMGDSEIFAVIAK 5481

Query: 1549 EAGLEQIQVLED---RSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVS 1605
            ++ +    ++E+   +S Y  +    +V    P     + +     G  A+F+   +   
Sbjct: 5482 KSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQ--CLVRG 5539

Query: 1606 DATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
                 V WY + K L  G RFT E +  GF  L I S +  D G Y C A N  G A
Sbjct: 5540 SPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 5595



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 93/202 (46%), Gaps = 33/202 (16%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK-HEIITTHNHTTLR 324
            PKI ++ ++  + +G+DA F+V++ G P P   W+KNG ++  S++ +      N   L 
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +R+    DS    + A N          +A E+ + +++  Q  Q IT TQ+ +      
Sbjct: 2138 IRDVTAEDSASIMVKAIN----------IAGETSSHAFLLVQAKQLITFTQELQD----- 2182

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                        V +++D     M  F+C  T  P+ +V W+ +  ++ +   ++ + ++
Sbjct: 2183 -----------VVAKEKDT----MATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSD 2225

Query: 445  SGNHALMITNVTLSDSGVVTCV 466
               H L I  +  SD+   +CV
Sbjct: 2226 RKVHFLSILTIDTSDAEDYSCV 2247



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +  L  +  + G    F C V   R P  KI W+   + L +G + K  HD    +L + 
Sbjct: 3242 LQELQPVTVQSGKPARF-CAVISGR-PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI 3299

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSL 2863
              + ED+ +YTC+A N  G ATTS SL
Sbjct: 3300 EAFPEDAAVYTCEAKNDYGVATTSASL 3326



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 12/225 (5%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFRTFCDFGFV 3478
            P F +P+ + + + E  +A F+  +     P +K  WY     ++  + ++    + G  
Sbjct: 5380 PRFIMPICDFK-IPENSDAVFKCSVIGIPTPEVK--WYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
             L+I      DS  Y CRA N  GEA+    + +       + ++  K    ++ +   L
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496

Query: 3539 EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGK 3598
            +  S   D+         PP F    SD      ++A+F+C  +        V W+ +GK
Sbjct: 5497 K--SNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC--LVRGSPRPTVYWYKDGK 5552

Query: 3599 PLLTGSRVKTINDFG--FVILEIGGVYQRDAGLYTCKATNRHGEA 3641
             L+ G R  T+ + G  F  L I  + + D G Y C ATN+ G A
Sbjct: 5553 -LVQGRRF-TVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 5595



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 70/271 (25%), Positives = 100/271 (36%), Gaps = 31/271 (11%)

Query: 2339 SIISESQRPEGLEKI--RELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTAH 2395
            SI   + R E  E +  RE +  E  + P   E PVT   P     L+N+  I EG++  
Sbjct: 905  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTP--PTLVSGLKNVTVI-EGESVT 961

Query: 2396 FDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
             +C +     PT  V W+R +  IE S     T   G   + I     ED G + C A N
Sbjct: 962  LECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVN 1019

Query: 2456 LLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLT 2515
              G                + ET         +K     +R  E  D        T+   
Sbjct: 1020 EAGTVSTSCYLAVQVSEEFEKET-----TAVTEKFTTEEKRFVESRDVVMTDTSLTEEQA 1074

Query: 2516 GPSE--------------LWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            GP E              L EG    +  +V   G+P     W  +GV L  G R++ ++
Sbjct: 1075 GPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSY 1132

Query: 2562 D--FGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +   G   L I+   A+DAG Y     N+ G
Sbjct: 1133 NKQTGECKLVISMTFADDAGEYTIVVRNKHG 1163



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 7/117 (5%)

Query: 1289 QLLEDAARRTKQVREDITVMQAPQ--FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEW 1346
            +LLE+       V  DI+  +A +  F   + N   +EG  V   C++   G    ++ W
Sbjct: 1269 ELLEEDGEEKMAV--DISESEAVESGFDSRIKNYRILEGMGVTFHCKMS--GYPLPKIAW 1324

Query: 1347 FCNGKPIKTGHRFRPAYEFD-YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            + +GK IK G R++  +  D   +L +  V PED G+YT  A+N  G A+ S  L V
Sbjct: 1325 YKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1381



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 4737 PAQFKTQITSKIKPT--IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            PA F+ ++T    PT  ++WL +G  +      +MI+E     L  G  Y  D+G  TCR
Sbjct: 1719 PAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCR 1778

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            AT   G   TSA L+VK +
Sbjct: 1779 ATNKYGTDHTSATLIVKDE 1797



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 59/251 (23%), Positives = 92/251 (36%), Gaps = 38/251 (15%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   Q LQ +  +Q G+ A F C +I  G P  K+ W++ E+L+    +    HD    +
Sbjct: 3239 PQVLQELQPV-TVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495
            + +     ED  VY C A N  G                 L  + PE +           
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSAS----------LSVEVPEVVS---------- 3335

Query: 2496 RRSEEPDREFEKPIFTQVLTGPSE---LWEGQHAHYEARVVPVGDPSLRFEWYINGVELK 2552
                 PD+E   P++   +  P +     EGQ A ++ RV       L+  WY    ++K
Sbjct: 3336 -----PDQEM--PVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIK 3385

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMR 2612
                FR T       L+I      D G Y   A N  G               I+ + + 
Sbjct: 3386 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIE 3445

Query: 2613 PESWEQIQLKE 2623
             E   ++++KE
Sbjct: 3446 QEI--EMEMKE 3454



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 5/104 (4%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F++  + ++V EG    F C   G P P VTW+ ND  I    N   +++   N++++
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPI--PRNQNFIIHSLENYSIL 4001

Query: 452  -ITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQVVAPK 492
             +++V   + G +TCV  N+ G  +T    ++   +K  V A K
Sbjct: 4002 TLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHK 4045



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 7/86 (8%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF---GFAALDILTVYG 1911
            ++ EG    + C++  YP P  ++ WY +GK ++ G RY+   DF   G A+L I  V  
Sbjct: 1301 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLP 1356

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            ED G YT  A N  G A+ S +L V+
Sbjct: 1357 EDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 96/395 (24%), Positives = 167/395 (42%), Gaps = 34/395 (8%)

Query: 1424 LEDTSRYK-KTDIIDESVTIKPRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLK-VE 1479
            L+D   Y  K      S  +K   V   K+++N  V E Q   F  +L   T  N+K V+
Sbjct: 2683 LDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL---THPNVKGVQ 2739

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W KNG  +    ++         +L I +    D  +Y  R    +G    S RL    T
Sbjct: 2740 WIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFR----LGRLGASARLHVE-T 2794

Query: 1540 TDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599
              I++  ++   LE   V  + S  H T  V        I   S K+  + E +      
Sbjct: 2795 VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEI-KPSDKHRLVSERKVHKLML 2853

Query: 1600 RLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPED-SGTYTCRA--I 1655
            + I  SDA    E+      L+  ++ F ET +      +I   +PE  + ++ C     
Sbjct: 2854 QNISPSDAG---EYTAVVGQLECKAKLFVETLHITKTMKNIE--VPETKTASFECEVSHF 2908

Query: 1656 NALGEAVTSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV---ITQAP 1711
            N     + +G+ I  S+K  I ++ +    +      ED+++Y      D+V   +T  P
Sbjct: 2909 NVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTP 2968

Query: 1712 VF-TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            +  T  +KDI   E     FE   + V    +  +WL+NGV I+++++          +L
Sbjct: 2969 IMITSMLKDINAEEKDTITFE---VTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSL 3025

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            N++ V+  D+  YT  A    G+A +++TL+V+++
Sbjct: 3026 NIRNVHFGDAADYTFVA----GKATSTATLYVEAR 3056



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 2/130 (1%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           Q   T E +  +E A  P FV+  Q   V +G   R   RVTG P P V ++ +  +I+ 
Sbjct: 88  QATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             + +I   E   ++L+I      DSG  +  A N  G       L V  +E+V A K  
Sbjct: 147 SLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTK 205

Query: 495 ERFSTLNVRE 504
              ST  + E
Sbjct: 206 TIVSTAQISE 215



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F++ LQ +  +++G     + ++T +  PT  V++Y+DG  I +S            S
Sbjct: 104 PNFVQRLQSM-TVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I     ED+G+Y+V A N +G A STA + V     V A
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPA 201



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L S+  +++G +   + RV  I  P   + ++ +G +I++   ++ + +    +
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
            L I   Y EDSGTY   ATN +G A +T  L V G   +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 4/114 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYRTSNDFG 1900
            +AP+   ++   T + +G  AH+  R+   PDP    EWY NG K+ +S   Y    +  
Sbjct: 2076 EAPKIFERIQSQT-VGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERSDRIYWYWPEDN 2132

Query: 1901 FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
               L I  V  EDS     KAIN  G+  S   L VQ+K+ I    + +  + K
Sbjct: 2133 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2186



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 35/166 (21%), Positives = 69/166 (41%), Gaps = 3/166 (1%)

Query: 1775 VNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRRE 1834
            + P  S ++      E  E + S  +       LQL +       K +Q E++ R+    
Sbjct: 3875 ITPHASESFGTLVNVEESEEIASERIKKDDLRELQLSASTRIDEFKTEQKEENMRFFENS 3934

Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
              +      P F+ ++    ++ EG S ++ C  + YP P   V WY N   +     + 
Sbjct: 3935 FRKRPQRCPPSFLQEIESQ-EVYEGDSCNFVCHFQGYPQPI--VTWYNNDMPIPRNQNFI 3991

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
              +   ++ L + +V+ ++ G  TC   N  G   ++  L V++K+
Sbjct: 3992 IHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQ 4037



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 2/125 (1%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +PP   Q+ ++  +++G+  + QV+++G P P V ++++G  + +S   +I    +  +L
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +      DSG Y++ A N  G   ++  L V+   E  V  ++++ I  T Q     + 
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG--EEEVPAKKTKTIVSTAQISESRQT 219

Query: 384 EISEK 388
            I +K
Sbjct: 220 RIEKK 224



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 59/243 (24%), Positives = 102/243 (41%), Gaps = 13/243 (5%)

Query: 1299 KQVREDITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            K+++ D+ V + P +F   + + +  E ++   +C +  +G  T  V+W+     I+  +
Sbjct: 5367 KELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDN 5424

Query: 1358 -RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
             ++  + E     L + +V   DS  Y C+A N +GEA+    L  +   ++       S
Sbjct: 5425 IKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL-TMGDSEIFAVIAKKS 5483

Query: 1417 GLEKIQYLED---TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTD 1473
             +     +E+    S Y  +    + V   PRF+         I G   +F+C +     
Sbjct: 5484 KVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLVR--GS 5540

Query: 1474 SNLKVEWFKNGQPVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
                V W+K+G+ V  G RF       G+  L I  L+  D G Y C A N  G  E   
Sbjct: 5541 PRPTVYWYKDGKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFA 5599

Query: 1533 RLT 1535
             LT
Sbjct: 5600 ALT 5602



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 48/201 (23%), Positives = 80/201 (39%), Gaps = 9/201 (4%)

Query: 2672 PNLKIEWFKNGVTLTT-GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P  +++W+K  + +     +   + + G  TL I ++   DS  Y C+A N +GEA+   
Sbjct: 5407 PTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRG 5466

Query: 2731 SIKIEDRHWLL----GESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCK 2786
             + + D            +   SL     L                   FI  +++    
Sbjct: 5467 FLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAP 5526

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSLDITHTYEEDSGI 2845
             G   +F+C V  S  PT  + W+ + K L  G R+      + + +L IT   + D G 
Sbjct: 5527 IGTAAYFQCLVRGSPRPT--VYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGE 5583

Query: 2846 YTCKATNSKGSATTSGSLRCT 2866
            Y C ATN  G A +  +L  T
Sbjct: 5584 YRCVATNKSGMAESFAALTLT 5604



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L ++  +R+G     + R+T    P +K  +Y +G  +++   F+   +     
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            L I+  YPEDSG Y   A N+ G A +TA + VQG+  +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 56/259 (21%), Positives = 98/259 (37%), Gaps = 12/259 (4%)

Query: 2887 VEQAEEARLAKGRRPSVPDTEYP-KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKI 2945
            V    EA++ +  R   P  E P  P  ++       ++EG+ + LE  +     P   +
Sbjct: 918  VLHGREAKVTETARVPAP-VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT--V 974

Query: 2946 EWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS 3005
             WY     +E    F++T   G   L + + +  DSG +TC A N+ G   TS  +    
Sbjct: 975  TWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 1034

Query: 3006 KDNLIERT---QHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD-IS 3061
             +   + T        TE    +++ +  +      +     G P     + K +V  + 
Sbjct: 1035 SEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLV 1094

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTTDSG 3119
            EG    +   +   G+    + W  +G  +   +R +  Y    G   L I  T   D+G
Sbjct: 1095 EGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1152

Query: 3120 TYSCRATNKWGQAEISVKL 3138
             Y+    NK G+   S  L
Sbjct: 1153 EYTIVVRNKHGETSASASL 1171



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 6/136 (4%)

Query: 1803 QSKASLQLESQHESALQKIQQLEDSS-RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQS 1861
            +SK   Q E     A+ + Q  +    R+    D+    N+ P+ + ++    +  EG S
Sbjct: 4119 ESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSDI---TNEPPKMLQEMPKHARCREGDS 4175

Query: 1862 AHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
               EC I   P P   V W+ NG +L+   +++         L I  V  +DSG+Y C A
Sbjct: 4176 IILECLISGEPQPV--VTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVA 4233

Query: 1922 INNLGQAVSSIRLNVQ 1937
             NN G   S   L V+
Sbjct: 4234 ENNSGAVESVSDLTVE 4249



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 21/205 (10%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI- 694
            PP FI PL      E   + F   +E  G P   ++W +N   +E   R   + R G + 
Sbjct: 5182 PPSFIEPLTKRKVYENTTLGFIVEVE--GLPVPGVKWYRNKSLLEPDERI-KMERVGNVC 5238

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            SL++ ++   + GEY C AV+  G A++ A + + P+         P T Q++ + +   
Sbjct: 5239 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFD--- 5295

Query: 755  KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT 814
                   +E  TS R    + +    EL E     FE Q+  V+ P    E+  D + + 
Sbjct: 5296 -------LEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVP----EFTPDHKSMI 5344

Query: 815  ASSRITSIFNFGYVSLNIMHLRAED 839
             S     +  F +V  N+     ED
Sbjct: 5345 VS---LDVLPFNFVDPNMDSREGED 5366



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 11/122 (9%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKT 2428
            +T Q P FTQPLQ++  + EG TA F+  +   G P  +V WFR+ ++I  S+   +  +
Sbjct: 1    MTTQAPTFTQPLQSV-VVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQIS 57

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ 2488
               G   +TI  V   + G Y  +A+N  G+              ++ ET  P  ++++Q
Sbjct: 58   FSDGRAKLTIPAVTKANSGRYSLKATNGSGQ------ATSTAELLVKAETAPPNFVQRLQ 111

Query: 2489 KL 2490
             +
Sbjct: 112  SM 113



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 5/98 (5%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDF 2697
            QAP FT  L+S   ++EG     EA +     P  ++ WF++G  ++T     ++ +F  
Sbjct: 4    QAPTFTQPLQSV-VVLEGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G   L+I ++   +SG Y+ KATN  G+A STA + ++
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 1/118 (0%)

Query: 378  ETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            E +  ++ISE +A+   F    ++  + EG    F C+++G P P++ W+ + ++I+   
Sbjct: 1276 EEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE 1335

Query: 437  NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             +++   + G  +L I  V   D G+ T  A N  G      +L V     + AP ++
Sbjct: 1336 RYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1393



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 5/98 (5%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            EP P + +++ K+AR  +G +   E  + G P PVV+W +    L +  K+  ++ E   
Sbjct: 4156 EP-PKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKF--QFEEVNC 4212

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQP 163
               L IK +   D G+Y C A N  G  E++  + ++P
Sbjct: 4213 SHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEP 4250



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E +PP F Q  ++    QG   + + ++ G PTPVV + R  A +     + +    Q G
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQI---SQEG 156

Query: 128 DV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           D+ SLLI +  P D G Y+  A N  G A  +  +  +G
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L ++  ++G  +  +  V  +  PT  ++++ +   + S   ++ + +    SL I
Sbjct: 106  FVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               Y EDSG Y+  ATNS G AT++  L   G++ +    +  +       + ++ + R+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV--PAKKTKTIVSTAQISESRQTRI 221

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923
             K              E +I  AA  QL
Sbjct: 222  EKKIEAHFDARSIATVEMVIDGAAGQQL 249



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 37/116 (31%), Positives = 58/116 (50%), Gaps = 8/116 (6%)

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
            + LE+    K    I ES  ++  F +R K+   ++EG  V F CK+        K+ W+
Sbjct: 1269 ELLEEDGEEKMAVDISESEAVESGFDSRIKNYR-ILEGMGVTFHCKMSGYPLP--KIAWY 1325

Query: 1482 KNGQPVTIGHRFRPIHDF---GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            K+G+ +  G R++   DF   G  +L I  ++ ED GIYT  A N+ G    S +L
Sbjct: 1326 KDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL 1379



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/89 (37%), Positives = 42/89 (47%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH-DFSYVSLD 2834
            F S + N    EG  + F C +  S  P  KI W+ + K +  G RY+         SL 
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKM--SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLR 1350

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I     ED GIYT  A+N KG+A  SG L
Sbjct: 1351 IPVVLPEDEGIYTAFASNIKGNAICSGKL 1379



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 5/107 (4%)

Query: 2355 ELESAEPFKRP-EIPEPVTRQRPV-FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEW 2412
            E+  ++ F  P E  EP   + P  F +PL     + E  T  F   +   G P   V+W
Sbjct: 5160 EIWRSDSFGTPNEAIEPKDNEMPPSFIEPLTK-RKVYENTTLGFIVEV--EGLPVPGVKW 5216

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +RN+ L+E   RI         S+ IS+++  + G YMC A N++GE
Sbjct: 5217 YRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGE 5263



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 65/316 (20%), Positives = 120/316 (37%), Gaps = 20/316 (6%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PPSF    ++  V  G          G     V W  N   + P  +N I+     Y++L
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPI-PRNQNFIIHSLENYSIL 4001

Query: 4573 ILEA-YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP--EIIEPL 4629
             L + + Q+ G   CV  N  G  +       S+   K K K   KA   P   + ++  
Sbjct: 4002 TLSSVHHQNEGSITCVLFNQYGTVK-----TTSMLKVKAKQKHDVKAHKVPVFHDYLDEE 4056

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
            ++  +   QA      +  +    +   K +  + PS   ++     E  +  +   PE 
Sbjct: 4057 EELALVFDQAKGAHPSMSQEGQTNLHLLKTNPPVPPSGDTELLSFPVEIQVTAATPIPEQ 4116

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQ-----ADNLPALTP--LRDIVVY----EGQPA 4738
            + + K V            + +VTQ  +       ++    P  L+++  +    EG   
Sbjct: 4117 DKESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSI 4176

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              +  I+ + +P + W + G L+ +   FQ      +  L I +   +D+G + C A   
Sbjct: 4177 ILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENN 4236

Query: 4799 AGQVETSAKLVVKSKT 4814
            +G VE+ + L V+  T
Sbjct: 4237 SGAVESVSDLTVEPVT 4252



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 27/116 (23%), Positives = 49/116 (42%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   Q+  + ++ EG    F     G P+P VTW+ N   +  +    I +  N++ L 
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILT 4002

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
            + +    + G  T +  N  G + T+  L V++  +  V+  +     D    E E
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYLDEEEE 4058



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            +PP      KN    +G +   E  + G P+P V+W R+   +     + + +  Q+G  
Sbjct: 941  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF--QSGIA 998

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             L+I++    D G +TC+A N+ G    S Y+
Sbjct: 999  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL 1030



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 12/173 (6%)

Query: 3050 FTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLE 3109
            FT   +D+V   +  +A +E     T +  + ++W+ +G  +    + R      +  L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3110 ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHF 3169
            IL   T+D+  YSC         + +VK       +G    F   +Q+IE + +  S   
Sbjct: 2233 ILTIDTSDAEDYSCVLVE-----DENVKTTAKLIVEGAVVEFVKELQDIE-VPESYSGEL 2286

Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            EC V P    +++ +WYHN   ++ + +    S  G   L +      D GEY
Sbjct: 2287 ECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2336



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 405  EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE-SGNHALMITNVTLSDSGVV 463
            EG     +C ++G P P VTWF N   ++   N K    E + +H L I +V   DSG  
Sbjct: 4172 EGDSIILECLISGEPQPVVTWFQNGVLLKQ--NQKFQFEEVNCSHQLYIKDVNSQDSGKY 4229

Query: 464  TCVARNKSG 472
             CVA N SG
Sbjct: 4230 KCVAENNSG 4238



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI  +    V E+  + F   VE    P   ++WYRN  LL    R +        S
Sbjct: 5182 PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDERIKMERVGNVCS 5239

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L+I  +   + GEY+C AVN  GE
Sbjct: 5240 LEISNIQKGEGGEYMCHAVNIIGE 5263



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 49/204 (24%), Positives = 80/204 (39%), Gaps = 8/204 (3%)

Query: 2535 VGDPSLRFEWYINGVELKMGS-RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXX 2593
            +G P+   +WY   + ++  + ++  + + G  TL I +V  +D+  Y C+A+N  G   
Sbjct: 5404 IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAI 5463

Query: 2594 XXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAM--NKVPEMFVDTGVQQAPIFTTHLKSY 2651
                            A + +      ++E  +  N     F    V+  P F   +   
Sbjct: 5464 CRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDC 5523

Query: 2652 DKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRND 2710
               + G   Y +  V  R  P   + W+K+G  L  G R        G   L I SL   
Sbjct: 5524 YAPI-GTAAYFQCLV--RGSPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKS 5579

Query: 2711 DSGIYTCKATNLLGEAVSTASIKI 2734
            D G Y C ATN  G A S A++ +
Sbjct: 5580 DEGEYRCVATNKSGMAESFAALTL 5603



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 69   PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
            P PP   Q  +      G  A+F   + G P P +SW +++  L    K    ++ Q  +
Sbjct: 3236 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQ--E 3293

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
             +LL+ +  P D   YTC A+N YG A  S  +  E
Sbjct: 3294 YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F+ +++S TV +   VR + RV     P   +++YR+G  + S   ++   +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDL 158

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             SL I   Y EDSG Y   A N  G   + A +
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 68/276 (24%), Positives = 108/276 (39%), Gaps = 37/276 (13%)

Query: 2904 PDTEYPK-PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            PD E P  P  II    +    EGQ    + +V   +  DLK+ WY   K ++    F++
Sbjct: 3336 PDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRM 3392

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLI-ERTQHPKGTEG 3021
            T       L++ + Y  D G YT  A N  G+  +++ +   + ++++ ER +     E 
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEM 3452

Query: 3022 LE-----KIQNLEDSLRKEPGQQPDDD---------------TGRPPE-FTTVFKDIVD- 3059
             E     + ++ E   R       D D               T   PE F   F   +  
Sbjct: 3453 KELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTF 3512

Query: 3060 --ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV-----VLEILG 3112
              + EG+   +   LI      M   WF+N + I    R R + A   +      LEI  
Sbjct: 3513 KYVLEGEPVVFTCRLIACPTPEMT--WFHNNRPIPTGLR-RIIKAESDLHHHSSSLEIKR 3569

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK 3148
             +  DSG+Y   A N  G AE +  L  + K + +K
Sbjct: 3570 VQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEK 3605



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY---- 4678
            P   + L  K V EG+ + F+C+++  P P + W+  ++ I       +   +D +    
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            +L I      D G Y+ +A NS G     A L V Q  Q
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQ 3602



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 12/139 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-- 2164
            Q P F   L S+  L EG  A FE  +     P   + WF +GQ I           F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSD 60

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
            G   L I      +SG Y  KATN  G+A +T  L V        +T  PN +++++ + 
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------ETAPPNFVQRLQSMT 114

Query: 2225 A-QGHSTRIEVEEPKISPP 2242
              QG   R++V    I  P
Sbjct: 115  VRQGSQVRLQVRVTGIPTP 133



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 4/130 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P F   ++ + V +      + R+   G P   V++ R+G  I++S       +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L +    PEDSGTY+  A N +G A +++ L VQ +   ++ ++    +    Q+ +S
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--EVPAKKTKTIVSTAQISES 216

Query: 1828 SRYQRREDVE 1837
             + +  + +E
Sbjct: 217  RQTRIEKKIE 226



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 4/134 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+  L+S+T  +G ++  + R+   G PT  +++ ++G  I++S  F         S
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
           L +     +DSG Y+  A ++ G A + A L V  +   E  ++  +T+    Q+ +  +
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV--QGEEEVPAKKTKTIVSTAQISESRQ 218

Query: 756 YQHQESIEEQTSQR 769
            + ++ IE     R
Sbjct: 219 TRIEKKIEAHFDAR 232



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 7/136 (5%)

Query: 3658 EPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDC 3717
            E QL +  +      ++ EE +   E    +  +  PP F  EI+   +V EG   +F C
Sbjct: 3907 ELQLSASTRIDEFKTEQKEENMRFFENSFRKRPQRCPPSFLQEIESQ-EVYEGDSCNFVC 3965

Query: 3718 RVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGFIALDIDYIYARDAGEYTCRATNK 3775
              +  G P   + W++N  P        +H+L ++  + L    ++ ++ G  TC   N+
Sbjct: 3966 HFQ--GYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTLSS--VHHQNEGSITCVLFNQ 4021

Query: 3776 WGSATTTAKITCSAKR 3791
            +G+  TT+ +   AK+
Sbjct: 4022 YGTVKTTSMLKVKAKQ 4037



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 4/112 (3%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            E IE  +  + P F++    R V E     F   V G P P V W+ N   +  D   +I
Sbjct: 5172 EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPD--ERI 5229

Query: 441  LVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI-EKEQVVA 490
             +   GN  +L I+N+   + G   C A N  GE      ++++ ++E+VVA
Sbjct: 5230 KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVA 5281



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 2/107 (1%)

Query: 1834 EDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
            E +E   N+ P    +     K+ E  +  +   +E  P P   V+WY N  +L+   R 
Sbjct: 5172 EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDERI 5229

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            +        +L+I  +   + GEY C A+N +G+A S   +++  +E
Sbjct: 5230 KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQE 5276



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS--RFTSIFRFGYI 694
           P F  PL+SV  +EG    FE  I   G P  ++ W ++GQ I  S+       F  G  
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + ++   +SG Y+ +A + +G A + A L V
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/177 (24%), Positives = 73/177 (41%), Gaps = 12/177 (6%)

Query: 3346 YCYEENSGEYE---CVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKL--- 3397
            + Y E   EYE    +   K+ +D+         +E  I   + +L + +E  + K    
Sbjct: 1209 FVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLE 1268

Query: 3398 QTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWY 3457
            + LE+    +    + E +     F   + N   L EG    F  +++    P  K+ WY
Sbjct: 1269 ELLEEDGEEKMAVDISESEAVESGFDSRIKNYRIL-EGMGVTFHCKMSGYPLP--KIAWY 1325

Query: 3458 WNGKSLKAGSRFR-TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             +GK +K G R++  F   G   L I    PED G Y   A N  G A+ +  + V+
Sbjct: 1326 KDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 4/93 (4%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-DFGLVTL 2702
            F + +K+Y +++EG  V    ++     P  KI W+K+G  +  G R +  F   G  +L
Sbjct: 1293 FDSRIKNY-RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASL 1349

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             I  +  +D GIYT  A+N+ G A+ +  + +E
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 47/195 (24%), Positives = 74/195 (37%), Gaps = 7/195 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKN-RFTPIYDF 4028
            + PPRF+  I     + E     F+C +  +G P  +V+W+     +   N ++    + 
Sbjct: 5377 EMPPRFIMPI-CDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEK 5433

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIR 4088
            G   +    V   DS  Y CRA N  G    +  + T G   I +     K   ++  + 
Sbjct: 5434 GSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL-TMGDSEI-FAVIAKKSKVTLSSLM 5491

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            E         +   E      PP F+          G  A F C V G P+P V W  +G
Sbjct: 5492 EELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDG 5551

Query: 4149 NTIVNGSRYKLTYDG 4163
              +V G R+ +   G
Sbjct: 5552 K-LVQGRRFTVEESG 5565



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 48/197 (24%), Positives = 78/197 (39%), Gaps = 11/197 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGS-RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P  +++WY     +E  + ++ ++ + G  TL + +V   DS  Y C+A N  GEA    
Sbjct: 5407 PTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRG 5466

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDD---TGRPPEFTTVFKD 3056
              + T  D+ I      K    L  +  +E+ + K        +      PP F     D
Sbjct: 5467 --FLTMGDSEIFAVIAKKSKVTLSSL--MEELVLKSNYTDSFFEFQVVEGPPRFIKGISD 5522

Query: 3057 IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTT 3116
                  G  A+++   +  G     + W+ +GK ++           G   L I     +
Sbjct: 5523 CY-APIGTAAYFQC--LVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKS 5579

Query: 3117 DSGTYSCRATNKWGQAE 3133
            D G Y C ATNK G AE
Sbjct: 5580 DEGEYRCVATNKSGMAE 5596



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYVAL 1770
            F   +K+ R+ E     F  ++   G P  ++ W ++G  I+   R  +  + D G  +L
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQD-GRASL 1349

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
             +  V PED G YT  A N  G A+ S  L+V+  A L
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPL 1387



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 16/156 (10%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMS 1641
            +KN  I EG    F  ++   S   L K+ WY + K +K G R+  +    G  +L I  
Sbjct: 1297 IKNYRILEGMGVTFHCKM---SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1353

Query: 1642 CLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE-SQHEGALPRLNQLEDTSKYQRH 1700
             LPED G YT  A N  G A+ SG         +Y+E +   GA   +  LE  S+ +  
Sbjct: 1354 VLPEDEGIYTAFASNIKGNAICSG--------KLYVEPAAPLGAPTYIPTLEPVSRIR-- 1403

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
            S     ++++P+   P +      + A    AR+ P
Sbjct: 1404 SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSP 1439



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 62/230 (26%), Positives = 94/230 (40%), Gaps = 17/230 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN-RIQTYHDFGYV 1101
            PRF+ P+    KI E   A F+  V      T  V+WY     I   N +     + G  
Sbjct: 5380 PRFIMPICDF-KIPENSDAVFKCSVIGIP--TPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEE-- 1159
             L I +V   DS  Y   A N  GEA     +T+   S I      +     +  +EE  
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGD-SEIFAVIAKKSKVTLSSLMEELV 5495

Query: 1160 --SKFVEPMYQIEEISKSKPVFVQPLSNP-PPVSEGKNIHLECRLEPMGDPTMRVEWFHN 1216
              S + +  ++ + + +  P F++ +S+   P+  G   + +C +   G P   V W+ +
Sbjct: 5496 LKSNYTDSFFEFQVV-EGPPRFIKGISDCYAPI--GTAAYFQCLVR--GSPRPTVYWYKD 5550

Query: 1217 GRSVTVGSRFKTYYD-FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
            G+ V  G RF       GF  L I     +D GEY   A N  G A + A
Sbjct: 5551 GKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFA 5599



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +   +     G  A F+  +RG+P P V W  K   LV+  ++++     TG  +
Sbjct: 5513 PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWY-KDGKLVQGRRFTVE-ESGTGFHN 5570

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEA 155
            L I  +   DEGEY C A N+ G A
Sbjct: 5571 LFITSLVKSDEGEYRCVATNKSGMA 5595



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 3430 ENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPE 3488
            + + +G +AHF  R+    DP  + EWY NG  ++   R   +     V  L I     E
Sbjct: 2087 QTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2144

Query: 3489 DSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            DS   + +A N  GE  + A + VQ K+ I    +L   +    D +A  E
Sbjct: 2145 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFE 2195



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHD 1097
            TQ P F  PL+    ++EG +A FEA +         V W+ +G+ I+++    +Q    
Sbjct: 3    TQAPTFTQPLQSV-VVLEGSTATFEAHISGFP--VPEVSWFRDGQVISTSTLPGVQISFS 59

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             G   L I +V   +SG Y++ A N +G+A  +A + V+  ++
Sbjct: 60   DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 11/139 (7%)

Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            +IE+  P +  P+    ++  T V +G  AHF  +V  V  P+   E+Y NG  ++ + R
Sbjct: 2068 KIELS-PSMEAPKIFERIQSQT-VGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDR 2123

Query: 2291 FHITFDFGYV-SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG 2349
             +  +    V  L I+    ED+    VKAIN  G  +S   + V AK  I    +  + 
Sbjct: 2124 IYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDV 2183

Query: 2350 LEKIR------ELESAEPF 2362
            + K +      E E++EPF
Sbjct: 2184 VAKEKDTMATFECETSEPF 2202



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            V   KI +KP++    E A   F+V +S +  P V WF     +  S+KH +++      
Sbjct: 2792 VETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHK 2850

Query: 323  LRVRNTQKSDSGHYT 337
            L ++N   SD+G YT
Sbjct: 2851 LMLQNISPSDAGEYT 2865



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 8/109 (7%)

Query: 3809 KELERGRISDAPKEE-----PIVSTPPKFITQIKSHT-VEESEGVRFECRVEPKEDPKLR 3862
            K + + +++ +PK        I + PPK + ++  H    E + +  EC +  +  P   
Sbjct: 4132 KAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPV-- 4189

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            + W++NG LL    +++         L I  V ++DSG+Y C A N+ G
Sbjct: 4190 VTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSG 4238



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/108 (22%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +++ +  T  P     L+++ +++G +   + R+  +   T  V++Y +   ++S   F 
Sbjct: 94   ELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQ 151

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             +      +L I    PEDSGTY+  A N++G A ++   +V  ++ +
Sbjct: 152  ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 8/127 (6%)

Query: 619  ERARPYIPPGEEDRVYPPPQFIVP-----LKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            E  +  IP  + D++   P    P     ++S T  +G   HF  R+  VG P  + EW 
Sbjct: 2055 EEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRV--VGKPDPECEWY 2112

Query: 674  KNGQSIEASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            KNG  IE S R    +       L +  +  +DS     +A++  G   + A L V  + 
Sbjct: 2113 KNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172

Query: 733  TIERTSQ 739
             I  T +
Sbjct: 2173 LITFTQE 2179



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 10/131 (7%)

Query: 636  PPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            PP+ +  + K     EG  I  E  I   G+P   + W +NG  ++ + +F         
Sbjct: 4157 PPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSH 4214

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
             L +  +N QDSG+Y C A + +G  E+ + L V P  T    SQ  E +      E Y 
Sbjct: 4215 QLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEP-VTYRENSQF-ENIG-----EIYG 4267

Query: 755  KYQHQESIEEQ 765
            KY   + +++Q
Sbjct: 4268 KYSRDQQLQDQ 4278



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGY 2299
            P F   L+    V EG TA FE  +     P   + ++ +G+ + ++      I+F  G 
Sbjct: 6    PTFTQPLQSVV-VLEGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L I      ++G YS+KA N  G  TS   + V A+ +  +  QR + +   +  +  
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 2360 EPFKRPEIPEPVTR 2373
               +   IP PV +
Sbjct: 123  LQVRVTGIPTPVVK 136



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 1/115 (0%)

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            ++++   P  V     + V EGE      R  G P P++ W  +G  I  +   R+  DG
Sbjct: 1834 DQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1893

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRP 598
                LDI   K+ D    + TA+N  G    + +L            +R   PRP
Sbjct: 1894 -IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRP 1947



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 18/168 (10%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            KD+  +    +A +E S+      ++ ++WF+    I+ S + R V    +  L +    
Sbjct: 2802 KDVTALENATVA-FEVSV---SHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNIS 2857

Query: 3115 TTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174
             +D+G Y+       GQ      LEC  K   +    T  ++NIE + + ++A FEC V 
Sbjct: 2858 PSDAGEYTAVV----GQ------LECKAKLFVETLHITKTMKNIE-VPETKTASFECEVS 2906

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
              + P M   W  NG  +  S + K V       L I  T   DS EY
Sbjct: 2907 HFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEY 2951



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 44/181 (24%), Positives = 81/181 (44%), Gaps = 18/181 (9%)

Query: 2067 VKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTS-----LENL 2121
            ++V A + +     + + + + +ELE    P+    + P  R VFL+ +T+     L+ +
Sbjct: 4105 IQVTAATPIPEQDKESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEM 4164

Query: 2122 ------KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
                  +EGD    EC +    +P   + WF NG  ++   +++         L I    
Sbjct: 4165 PKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVN 4222

Query: 2176 AEDSGTYMCKATNKLG--EAVNTCTLKVAGHR-NIILDT--QHPNGLEKIRQLEAQGHST 2230
            ++DSG Y C A N  G  E+V+  T++   +R N   +   +      + +QL+ QG S 
Sbjct: 4223 SQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQFENIGEIYGKYSRDQQLQDQGESV 4282

Query: 2231 R 2231
            R
Sbjct: 4283 R 4283



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDF--G 3613
            P FT     +++ E S+A FE  +   PV +    V WF +G+ + T +       F  G
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQISFSDG 61

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
               L I  V + ++G Y+ KATN  G+AT + +L VK
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVS 130
            P+F +  KN    +G   + + +  GNP P + W  K + ++  +KY  +R     G+ +
Sbjct: 1556 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL-KNSDIIVPHKYPKIRIEGTKGEAA 1614

Query: 131  LLIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPE 164
            L I      D   YT TA N+ G     C V ++ E
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 20/69 (28%), Positives = 36/69 (52%)

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
            REG+ ++L     G P P +TW ++GV +  N + +      +  L I    + D+  Y+
Sbjct: 4171 REGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYK 4230

Query: 563  CTAQNVAGS 571
            C A+N +G+
Sbjct: 4231 CVAENNSGA 4239



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-- 3475
            +AP FT PL ++  L EG  A FEA ++    P  +V W+ +G+ +   +       F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            G   L I      +SG Y  +A N  G+A +TA + V+ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GF 3752
            P FT  ++ ++ V EG    F+  +   G P   + WF +G+  +T +       F  G 
Sbjct: 6    PTFTQPLQ-SVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L I  +   ++G Y+ +ATN  G AT+TA++   A+
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 3/153 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T E +V+   A  PP FV    ++TV +G   R   RVTG P P V +  +G  I +   
Sbjct: 92   TAELLVKAETA--PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 4157 YKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
            ++++ +G +Y   I +    D+G   V              L V    +      K    
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVID 4248
                  ++  R E ++E  F+ R +   + VID
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVID 242



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F+ ++Q +T + +G     + R+  +  P +K  ++ +G ++     ++   +  + 
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLY 159

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             L I   Y E+SG Y   ATN +GR ++ A L    +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F     + +  +G  A+F+ K+ G P P   W      +V    + +   E  G  SL
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED-GTQSL 1515

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            +I    P D GE+T  A+N+ G +  SV +  E
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1548



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 87/362 (24%), Positives = 150/362 (41%), Gaps = 45/362 (12%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            +P  + +  S + V EG  V  E K   V+  +++  W K+GQ V    R   + D    
Sbjct: 2354 RPIAILQGLSDQKVCEGDIVQLEVK---VSLESVEGVWMKDGQEVQPSDRVHIVIDKQSH 2410

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L I D+  ED+G Y+   +  +G    S R++  S  D++        L+ + V+E   
Sbjct: 2411 MLLIEDMTKEDAGNYSF-TIPALGLS-TSGRVSVYSV-DVITP------LKDVNVIEG-- 2459

Query: 1563 KYHRTDMVDEVTTQAPICTTS---LKNVEIKEGQRAHFERRLIPVSDATLKVEWYH--NN 1617
                T  V E     P  T+    L + +IK   R    + ++  +   L +   H  + 
Sbjct: 2460 ----TKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVINRTHASDE 2512

Query: 1618 KPLKSGSRFTETN-NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS----- 1671
             P K      ETN N     + I+  L + + T T   +  + E   SGI ++ +     
Sbjct: 2513 GPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV-ELSHSGIDVLWNFKDKE 2571

Query: 1672 -KKSIYLESQHEGALPRLNQL----EDTSKYQRHSAQD----EVITQAPVFTMPMKDIRV 1722
             K S   + +  G + +L  L    +D  KY  ++ ++    ++       + P+ D  V
Sbjct: 2572 IKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPLTDQTV 2631

Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782
            AE+Q A FE     V +P  + EWLR+G  +  +N + +  D     L +     +D G 
Sbjct: 2632 AESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2688

Query: 1783 YT 1784
            YT
Sbjct: 2689 YT 2690



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F   ++ ++ V +G  V    RV   G PT  + ++ +G    +        +    
Sbjct: 103  PPNFVQRLQ-SMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            +L I   Y  D+G Y+  ATN  G AT+TA++    + ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FVQ L +   V +G  + L+ R+   G PT  V+++ +G  +     F+   +    +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I  A   D+G Y+V A N +G A TS    +++  + V   + +  +   Q+ E    
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRA-TSTAELLVQGEEEVPAKKTKTIVSTAQISESRQT 219

Query: 1297 RTKQ 1300
            R ++
Sbjct: 220  RIEK 223



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 20/94 (21%), Positives = 40/94 (42%)

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            K+  + P F+E  +   V E   +       G P P + W ++   + P+  +++   G 
Sbjct: 5177 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 5236

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +L+I   +  +   Y C A N+ G   + A +
Sbjct: 5237 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 5270



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGYVALDIASVRAED 1112
            +I+EG    F  ++         + WY +GK+I    R Q  +   G  +L I  V  ED
Sbjct: 1301 RILEGMGVTFHCKMSGYP--LPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358

Query: 1113 SGVYTVVARNAAGEAQLSASMTVE 1136
             G+YT  A N  G A  S  + VE
Sbjct: 1359 EGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF-NFGYVSLNIMHLRAEDAGS 842
            EG    F  +++    P  ++ WYKDG+ I    R    F   G  SL I  +  ED G 
Sbjct: 1304 EGMGVTFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361

Query: 843  YTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
            YT  A N  G AI +  + V   + + A   IP
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP 1394



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 3/87 (3%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V   Q   F  +L       +   A +EC      +P ++V+WY +G  +  G +YR  +
Sbjct: 2168 VQAKQLITFTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHS 2224

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINN 1924
            D     L ILT+   D+ +Y+C  + +
Sbjct: 2225 DRKVHFLSILTIDTSDAEDYSCVLVED 2251



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 42/185 (22%), Positives = 74/185 (40%), Gaps = 8/185 (4%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY---- 4569
            PSFT       V  G+ V    ++      ++ W  N + +   +R  I  E   +    
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            +L I     +DSG Y  +AINS G A   A  +V      +K     K A    E +E L
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAERTHENVEAL 3623

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
             ++   E + I+   +  G P    Q  +   +++ + +F+   +A +      E + E 
Sbjct: 3624 VER--GEDR-IKVDLRFTGSPFNKKQDVEQKGMMR-TIHFKTMSSAKKTDYMYDEEYLES 3679

Query: 4690 EGDYK 4694
            + D +
Sbjct: 3680 KSDIR 3684



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 4/127 (3%)

Query: 2609 QAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEP 2668
            + + P++  Q Q+ ++  ++   +F+     + P     +  + +  EG  + LE  +  
Sbjct: 4127 EELEPKAMPQDQVTQSPKHRF--VFLSDITNEPPKMLQEMPKHARCREGDSIILECLISG 4184

Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
               P   + WF+NGV L    + +         L I  + + DSG Y C A N  G   S
Sbjct: 4185 EPQP--VVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVES 4242

Query: 2729 TASIKIE 2735
             + + +E
Sbjct: 4243 VSDLTVE 4249



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 16/115 (13%)

Query: 4080 HMKSIEK--IREMEASW-QVTPEQVVEESKARCPPVFVSLPDAVT-----------VEEG 4125
            H+ S E+  I+E+E    + T E+++EE       V +S  +AV            + EG
Sbjct: 1246 HISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEG 1305

Query: 4126 EWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYDTG 4178
                F C+++G+P P++ W  +G  I +G RY++ +  DG     IP     D G
Sbjct: 1306 MGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1360



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLR--GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            P F++   + R  + G A FE +L   G+PT VV W     PL   N+  +R   + G  
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR--LRMINEFGYC 1760

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL        D G  TC A N+YG
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYG 1784



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/128 (22%), Positives = 52/128 (40%), Gaps = 3/128 (2%)

Query: 3251 SLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVD 3310
            S + D     ++ E+++  +      P   PP F+ +I+   ++ EG S +F        
Sbjct: 3913 STRIDEFKTEQKEENMRFFENSFRKRPQRCPPSFLQEIES-QEVYEGDSCNFVCHFQGYP 3971

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
             P   V W+ N   +P    +         IL +   + +N G   CV  N+ G   T +
Sbjct: 3972 QPI--VTWYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTS 4029

Query: 3371 NLKCTSKE 3378
             LK  +K+
Sbjct: 4030 MLKVKAKQ 4037



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 44/168 (26%), Positives = 72/168 (42%), Gaps = 10/168 (5%)

Query: 1671 SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPM-KDIRVAENQAAH 1729
            SK+    E     A+P+ +Q+  + K+ R     ++  + P     M K  R  E  +  
Sbjct: 4120 SKEVFQTEELEPKAMPQ-DQVTQSPKH-RFVFLSDITNEPPKMLQEMPKHARCREGDSII 4177

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
             E  +   G+P+  V W +NGV ++ + +           L +K VN +DSG Y C A N
Sbjct: 4178 LECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAEN 4235

Query: 1790 ELGEAVTSSTLFVQS---KASLQLESQHE--SALQKIQQLEDSSRYQR 1832
              G   + S L V+    + + Q E+  E      + QQL+D     R
Sbjct: 4236 NSGAVESVSDLTVEPVTYRENSQFENIGEIYGKYSRDQQLQDQGESVR 4283



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 2/82 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+ E   +    +VE    P +K  W++N   L    R+K      + +L I++++  + 
Sbjct: 5193 KVYENTTLGFIVEVEGLPVPGVK--WYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEG 5250

Query: 2713 GIYTCKATNLLGEAVSTASIKI 2734
            G Y C A N++GEA S A++ I
Sbjct: 5251 GEYMCHAVNIIGEAKSFANVDI 5272



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033
            + P F +P+++  V EG     EA ++    P   V W+ +G+ +        + ++  G
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
               L I      ++G Y  KATN  G+A +T+ + V A++
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFD 1366
            QAP F++ L ++  +EG+    E  +   G     V WF +G+ I T      + ++   
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
               L + +V   +SG Y+ +ATN  G+A ++  L V A+
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/97 (32%), Positives = 48/97 (49%), Gaps = 7/97 (7%)

Query: 2944 KIEWYFNGKVLEQGSRFKLTSDF---GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            KI WY +GK ++ G R+++  DF   G  +L +  V   D GIYT  A N +G A  S  
Sbjct: 1321 KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGK 1378

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLED-SLRKEP 3036
            +Y      L   T  P   E + +I++L   S+ + P
Sbjct: 1379 LYVEPAAPLGAPTYIPT-LEPVSRIRSLSPRSVSRSP 1414



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 37/118 (31%), Positives = 50/118 (42%), Gaps = 5/118 (4%)

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            +P  IE     + P     + S + + +G  AHF  RV    DP    +W+ NG KI   
Sbjct: 2065 KPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERS 2121

Query: 2156 HR-YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQ 2212
             R Y    +     L I    AEDS + M KA N  GE  +   L V   + +I  TQ
Sbjct: 2122 DRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA-KQLITFTQ 2178



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/119 (23%), Positives = 50/119 (42%), Gaps = 2/119 (1%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +  Q E+  ++  +S +       P F   ++   V E  + +F       G P+  V W
Sbjct: 3920 KTEQKEENMRFFENSFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHF--QGYPQPIVTW 3977

Query: 1747 LRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
              N +PI  +          Y  L +  V+ ++ G+ TC   N+ G   T+S L V++K
Sbjct: 3978 YNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAK 4036



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/132 (21%), Positives = 58/132 (43%), Gaps = 8/132 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  + +    EGD+ +F C+ +    P   + W+ N+ P+P    +      +Y  L +
Sbjct: 3946 FLQEIESQEVYEGDSCNFVCHFQGYPQPI--VTWYNNDMPIPRNQNFIIHSLENYSILTL 4003

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
            +  + ++ G  TC   N  G+  T+  L+    +    D +  +     + +++ EE  L
Sbjct: 4004 SSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQK--HDVKAHKVPVFHDYLDEEEELAL 4061

Query: 2896 ----AKGRRPSV 2903
                AKG  PS+
Sbjct: 4062 VFDQAKGAHPSM 4073



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 33/116 (28%), Positives = 46/116 (39%), Gaps = 2/116 (1%)

Query: 2475 QLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVP 2534
            Q E   P+ M + Q  + P  R     D   E P   Q +   +   EG     E  +  
Sbjct: 4125 QTEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLIS- 4183

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             G+P     W+ NGV LK   +F+         L I  V + D+G Y C A N +G
Sbjct: 4184 -GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSG 4238



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 2785 CKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSG 2844
            C+EGD+I  EC +  S +P   + WF N   L    +++         L I     +DSG
Sbjct: 4170 CREGDSIILECLI--SGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSG 4227

Query: 2845 IYTCKATNSKGSATTSGSL 2863
             Y C A N+ G+  +   L
Sbjct: 4228 KYKCVAENNSGAVESVSDL 4246



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/84 (27%), Positives = 35/84 (41%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F Q  ++    +G  A FE  + G P P VSW R    +       ++ +   G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155
            I  +   + G Y+  A N  G+A
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA 89



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            T  P F+  L+    + +G     + RV      T  V++Y +G +I S+   Q   +  
Sbjct: 101  TAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQISQEGD 157

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
              +L IA    EDSG Y+V A N+ G A  +A + V+    +
Sbjct: 158  LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 4/113 (3%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF-RFGYISLDMLSL 701
            +K+   +EG  + F  ++   G P  KI W K+G+ I+   R+   F + G  SL +  +
Sbjct: 1297 IKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVV 1354

Query: 702  NIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
              +D G YT  A +  G A     L+V P A +   +  P TL+ + ++   S
Sbjct: 1355 LPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP-TLEPVSRIRSLS 1406



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 1/82 (1%)

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
            V EG+ A+F+ ++T   +P + W   G LI ++  F++ ++G +  L I +    DTG  
Sbjct: 1852 VLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIH-YLDIVDCKSYDTGEV 1910

Query: 4792 TCRATTAAGQVETSAKLVVKSK 4813
               A    G +E   KL ++ +
Sbjct: 1911 KVTAENPEGVIEHKVKLEIQQR 1932



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 4/99 (4%)

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            FK  +I    + + P   + +Q+   + +G  AHF  R+  VG P  + EW++N   IE 
Sbjct: 2064 FKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIER 2120

Query: 2422 SSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S RI     +     + I  V  ED    M +A N+ GE
Sbjct: 2121 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE 2159



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 3284 FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343
            F  ++QDV    +   A FE       +P +KV+W+ +G ++  G +YR   D  +  L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3344 ILYCYEENSGEYECV 3358
            IL     ++ +Y CV
Sbjct: 2233 ILTIDTSDAEDYSCV 2247



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 42/175 (24%), Positives = 68/175 (38%), Gaps = 13/175 (7%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            + +K  +D    E     F+  V+    P V WF    +I+    H+ LV+E   H LM+
Sbjct: 2796 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHR-LVSERKVHKLML 2853

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             N++ SD+G  T V     G+   +C+  +     V      +    + V E +      
Sbjct: 2854 QNISPSDAGEYTAVV----GQ--LECKAKLF----VETLHITKTMKNIEVPETKTASFEC 2903

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
                   P + W K+GV I  + + +I   G    L I      D+A Y     N
Sbjct: 2904 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2957



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 10/96 (10%)

Query: 771  QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS- 829
            +F + ++D+  L++ R A FE +   VS+P + V+W KD + +  + RI  I    YV  
Sbjct: 3059 EFRKHIKDIKVLEKKR-AMFECE---VSEPDITVQWMKDDQELQITDRI-KIQKEKYVHR 3113

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            L I   R  DAG YTV A    G  +STA + V  R
Sbjct: 3114 LLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3145



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/121 (23%), Positives = 51/121 (42%), Gaps = 3/121 (2%)

Query: 3396 KLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVE 3455
            K +  E++M R  + S  +   + P   +     + + EG++ +F         P   V 
Sbjct: 3920 KTEQKEENM-RFFENSFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPI--VT 3976

Query: 3456 WYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            WY N   +     F       + IL +S  + ++ G   C  +N YG   TT+ +KV+ K
Sbjct: 3977 WYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAK 4036

Query: 3516 R 3516
            +
Sbjct: 4037 Q 4037



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 10/133 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP FV ++QS T     + ++   Q+   G P   V+++ +G  +     F    +    
Sbjct: 103  PPNFVQRLQSMTV---RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP-KHMKSIEKIREM 4090
            ++     YPEDSG Y   ATN  G   + A +   G      + ++P K  K+I    ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EEEVPAKKTKTIVSTAQI 213

Query: 4091 EASWQVTPEQVVE 4103
              S Q   E+ +E
Sbjct: 214  SESRQTRIEKKIE 226



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            +E P+  + I++  V +G   H    +    DP    EWY NG  +++  R    +    
Sbjct: 2075 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDN 2132

Query: 2035 VA-LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            V  L I    AED+ + M KA N  GE  + + + V AK
Sbjct: 2133 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 49/206 (23%), Positives = 89/206 (43%), Gaps = 19/206 (9%)

Query: 4352 ESTVHGKEVHVAKQKQTQKEVVGDKEITRKITS---TETTEIEHKAQTQERVVEGPVKPS 4408
            ES +H +     + +  +    G+ E + + T    +++ +I+HK+   +R        S
Sbjct: 3437 ESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTS 3496

Query: 4409 K-----PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN------SPDF 4457
                   P FT+K+    V E E   F       P P + W+  N PI          + 
Sbjct: 3497 SWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAES 3556

Query: 4458 QIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT 4517
             +H  S  S L I++V   DS  +  +A N  G+A+ +A+L+V +K +  +         
Sbjct: 3557 DLHHHS--SSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAE 3614

Query: 4518 LTAQNVN--VTSGQ-LVRLDTKVTGT 4540
             T +NV   V  G+  +++D + TG+
Sbjct: 3615 RTHENVEALVERGEDRIKVDLRFTGS 3640



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F Q  ++    +G +  F    +G P P+V+W     P+     + +   E      
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYS--I 4000

Query: 131  LLIKQIGPGDEGEYTCTARNQYG 153
            L +  +   +EG  TC   NQYG
Sbjct: 4001 LTLSSVHHQNEGSITCVLFNQYG 4023



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 4/97 (4%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            D E P P +I P+  + ++ E   L    +VE    P +K  WY N  +LE   R K+  
Sbjct: 5178 DNEMP-PSFIEPLT-KRKVYENTTLGFIVEVEGLPVPGVK--WYRNKSLLEPDERIKMER 5233

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
                 +L++ ++ + + G Y C A N  GEA + + V
Sbjct: 5234 VGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 5270



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +TTQAP  T  L++V + EG  A FE  +   PV +    V W+ + + + + +      
Sbjct: 1    MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQI 56

Query: 1631 NF--GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            +F  G   L I +    +SG Y+ +A N  G+A ++   +V ++
Sbjct: 57   SFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 10/120 (8%)

Query: 3943 LTQMEATIKKYTSEVYLTEDD----LYDVDKKQPPR--FVTQIQSQTSLVEMETTKFECQ 3996
            + ++E  I K T E  L ED       D+ + +     F ++I++   L  M  T F C+
Sbjct: 1255 IKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVT-FHCK 1313

Query: 3997 LAPVGDPNMKVEWFFNGKPLLHKNRF-TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            ++  G P  K+ W+ +GK + H  R+       G  ++    V PED G Y   A+N+ G
Sbjct: 1314 MS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1371



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 46/180 (25%), Positives = 69/180 (38%), Gaps = 16/180 (8%)

Query: 396  KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
            K  ++ +V E K   F+C V+    P + W  N  +I      KI+V +   H L+I N 
Sbjct: 2886 KTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVV-QGKLHQLIIMNT 2943

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARA 514
            +  DS            E  F C  + +     V P  +      +N  E + +      
Sbjct: 2944 STEDSA-----------EYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEV-T 2991

Query: 515  VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            V        W K+GV I    + ++ T     +L+I      DAA Y   A   A STAT
Sbjct: 2992 VNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA-GKATSTAT 3050



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSL 2833
            F   L ++V  EG    FE ++  S  P  ++ WF + + + + T       FS     L
Sbjct: 8    FTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I    + +SG Y+ KATN  G AT++  L
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 15/157 (9%)

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA 4723
            K   Y ++ R   +  L  ++   E+E   K +A    G++T+       +PD+ +  P+
Sbjct: 2023 KDESYEELLRKTKDELLHWTKELTEEEK--KALA--EEGKITIPT----FKPDKIELSPS 2074

Query: 4724 LTP------LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNA 4776
            +        ++   V +G  A F+ ++  K  P  +W + G  I  +        E N  
Sbjct: 2075 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVC 2134

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             L+I +   ED+ +   +A   AG+  + A L+V++K
Sbjct: 2135 ELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 2244 FVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLD 2303
            FV EL+    V E  +   EC V P    N+  ++YHN   L+S  ++ IT   G  +L 
Sbjct: 2269 FVKELQDI-EVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 2304 IQHCVPEDAGEYS 2316
            ++    ED GEYS
Sbjct: 2325 VKDVTKEDQGEYS 2337



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
            L+++E+ E      E     VS   ++ +WYHN+  LKS  ++T T+  G   L +    
Sbjct: 2273 LQDIEVPESYSGELE---CIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVT 2329

Query: 1644 PEDSGTYT 1651
             ED G Y+
Sbjct: 2330 KEDQGEYS 2337



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 64/331 (19%), Positives = 127/331 (38%), Gaps = 35/331 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            K+    +     FE  +  +  PV  W  K   +   +K+ +    +     L+++ I P
Sbjct: 2802 KDVTALENATVAFEVSVSHDTVPV-KWFHKSVEIKPSDKHRLVSERKVH--KLMLQNISP 2858

Query: 139  GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
             D GEYT       G+  C   +  E                   + +E     T  +  
Sbjct: 2859 SDAGEYTAVV----GQLECKAKLFVE-----------TLHITKTMKNIEVPETKTASFEC 2903

Query: 199  EQSR-QTQKVAYTNGTDHSSTDDFKV---DTFEYRLLREVSFRESITKRYVGESDVQIST 254
            E S      +   NG +   ++ FK+         ++   S  +S    +V  +D Q+S 
Sbjct: 2904 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND-QVSA 2962

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
             +      V+P  I    ++   +E     F+V ++        W KNG  + +++K ++
Sbjct: 2963 TLT-----VTPIMITSMLKDINAEEKDTITFEVTVNYEGIS-YKWLKNGVEIKSTDKCQM 3016

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
             T     +L +RN    D+  YT +A    G   ++  L VE+    + +  +   + + 
Sbjct: 3017 RTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHIKDIKVLEK 3072

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTE 405
            ++   E   E+SE  +  Q++K  Q+  +T+
Sbjct: 3073 KRAMFE--CEVSEPDITVQWMKDDQELQITD 3101



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            +K++   E     FE  +     P+M   WLKNG  IE S +F  + +     L +++ +
Sbjct: 2888 MKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2944

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTP 730
             +DS EYT       G  +  A L VTP
Sbjct: 2945 TEDSAEYT----FVCGNDQVSATLTVTP 2968



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 760  ESIEEQTSQRP-QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
            E+IE + ++ P  FI PL    ++ E     F  ++  +  P   V+WY++   +    R
Sbjct: 5172 EAIEPKDNEMPPSFIEPLTKR-KVYENTTLGFIVEVEGL--PVPGVKWYRNKSLLEPDER 5228

Query: 819  ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQR 878
            I         SL I +++  + G Y   AVN +GEA S A++ +  +      L  P   
Sbjct: 5229 IKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTH 5288

Query: 879  RYI 881
            +++
Sbjct: 5289 QHV 5291



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 8/126 (6%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            FT  L ++    +   A FE     T +P +KV+WY +G  +  G ++R   D     L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK-RNIILESQ---LPKGMEGTIDKIAA 3537
            I      D+ +Y C    +     TTA + V+G     + E Q   +P+   G ++ I +
Sbjct: 2233 ILTIDTSDAEDYSCVLVED-ENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVS 2291

Query: 3538 LEGYSG 3543
             E   G
Sbjct: 2292 PENIEG 2297



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 7/89 (7%)

Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIAS 1107
            PLK  N ++EG  A  E +V    D+T +V+WY N +QI   +R+Q         L I  
Sbjct: 2450 PLKDVN-VIEGTKAVLECKVSVP-DVT-SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINR 2506

Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
              A D G Y ++     G  + + +++VE
Sbjct: 2507 THASDEGPYKLI----VGRVETNCNLSVE 2531



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F+ +I+S  V E +   F C  +    P   + WY N   +P    +       +  
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQP--IVTWYNNDMPIPRNQNFIIHSLENYSI 4000

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            L +  V+ ++ G   C   N +G   T + +  K
Sbjct: 4001 LTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVK 4034



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/150 (20%), Positives = 62/150 (41%), Gaps = 6/150 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F  P+   +V EN    F   +   G P   V+W RN   +E   R+         +L
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEV--EGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSL 5240

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK----ASLQLESQHESALQKIQQLED 1826
             +  +   + G Y C A+N +GEA + + + +  +     +L     H+  ++   +   
Sbjct: 5241 EISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHTT 5300

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856
            SSR    +++ + V  + + + +     K+
Sbjct: 5301 SSRTPSPQEIVLEVELSEKDVKEFEKQVKI 5330



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 9/149 (6%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G + +   L  +AE+  PP F      + + + S    + R+  +   +  V+++ +G  
Sbjct: 87   GQATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAE 143

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            + +    +   +     L I   Y  D+G Y+  ATN  G AT + +L V+G      E 
Sbjct: 144  IQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EE 197

Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIE 3688
            ++P+       S  ++ E+   R E  IE
Sbjct: 198  EVPAKKTKTIVSTAQISESRQTRIEKKIE 226



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/109 (22%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V   T  P F   ++  +++++G     + R+   G  T  V++ +DG  +++S      
Sbjct: 97   VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQIS 153

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                  +L I      D+G Y+  A N++G+AT++A L +  ++++ A+
Sbjct: 154  QEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+S   + +G  V L+ +V     P +K  ++++G  + +    + + +  L +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L I     +DSG Y+  ATN +G A STA + ++
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 19/163 (11%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSG 3119
            +E Q   +E  L  +G   + + W +  K I+ S + + + A G +  L +L     D G
Sbjct: 2545 TETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEG 2600

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             Y+  A       +++V    + K    +            + + Q A FEC V    +P
Sbjct: 2601 KYTFYAGENMTSGKLTVAGGAISKPLTDQT-----------VAESQEAVFECEVA---NP 2646

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            D K EW  +G+ +  +  I++ SD     L IA T+  D GEY
Sbjct: 2647 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY 2689



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY 4157
            RCPP F+   ++  V EG+   F C   G+P+P V W  N   I     +
Sbjct: 3941 RCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNF 3990



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 2/109 (1%)

Query: 2885 EAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLK 2944
            +A+ Q +  +  K R   + D     P+ +  +    +  EG  + LE  +    +P   
Sbjct: 4132 KAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLIS--GEPQPV 4189

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            + W+ NG +L+Q  +F+         L + DV  +DSG Y C A N  G
Sbjct: 4190 VTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSG 4238



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 2/106 (1%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            K   + + D    PP+   E+  +    EG  +  +C +   G+P   + WF NG     
Sbjct: 4144 KHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQ 4201

Query: 3741 GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
              +           L I  + ++D+G+Y C A N  G+  + + +T
Sbjct: 4202 NQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLT 4247



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 41/179 (22%), Positives = 67/179 (37%), Gaps = 13/179 (7%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D +V EG     +C+V+      V W++ND QI+ D   + +V +     L+I     S
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV-KGTKQRLVINRTHAS 2510

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D G    +     G     C L+V   E++   K +     L   E + VV       + 
Sbjct: 2511 DEGPYKLIV----GRVETNCNLSV---EKI---KIIRGLRDLTCTETQNVVFEVELSHSG 2560

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA-QNVAGSTATRA 576
               + W      I P+ + +I   G    L +      D   Y   A +N+     T A
Sbjct: 2561 ID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVA 2618



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/92 (28%), Positives = 42/92 (45%)

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            +GE   +++T    +   V   KI +  +N  + E  DA F V+L+      V W KNG 
Sbjct: 2686 IGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV 2745

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L ++ K+ I       +LR++N    D   Y
Sbjct: 2746 VLESNEKYAISVKGTIYSLRIKNCAIVDESVY 2777



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KDI+V E + A FE     V +P + V+W+++   ++ ++R+    +     L +
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLI 3116

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                  D+G YT  A    G  V+++ LFV+ +
Sbjct: 3117 PSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3145



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F+  ++S    EG   +F    +  G P   + W  N   I  +  F       Y  
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQ--GYPQPIVTWYNNDMPIPRNQNFIIHSLENYSI 4000

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + S++ Q+ G  TC   +  G  +T ++L V
Sbjct: 4001 LTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 18/150 (12%)

Query: 1165 PMYQIEEISKSKPVFVQPLSNPPP-----------VSEGKNIHLECRLEPMGDPTMRVEW 1213
            P  Q+ +  K + VF+  ++N PP             EG +I LEC +   G+P   V W
Sbjct: 4135 PQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTW 4192

Query: 1214 FHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273
            F NG  +    +F+         L I    S D+G+Y   A N+ G+  + + + V    
Sbjct: 4193 FQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTV---- 4248

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVRE 1303
            + VT  +N Q  E I  +     R +Q+++
Sbjct: 4249 EPVTYRENSQ-FENIGEIYGKYSRDQQLQD 4277



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 2233 EVEEPKIS--PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            E  EPK +  PP F+  L     V+E  T  F  +VE +  P   +++Y N   L+   R
Sbjct: 5172 EAIEPKDNEMPPSFIEPLT-KRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDER 5228

Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              +       SL+I +    + GEY   A+N +G   S  ++ +
Sbjct: 5229 IKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 5/133 (3%)

Query: 3183 IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++WY N   +    RIK         L+I+  Q  + GEY+C A N  GE  + A ++  
Sbjct: 5214 VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +    +    P +   + E +       +TPS     P + + +++   K V+      
Sbjct: 5274 PQEERVVALPPPVTHQHVMEFDLEHTTSSRTPS-----PQEIVLEVELSEKDVKEFEKQV 5328

Query: 3303 EARLVPVDDPDLK 3315
            +   VP   PD K
Sbjct: 5329 KIVTVPEFTPDHK 5341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 8/94 (8%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            F  H+K   K++E +    E +V   ++P++ ++W K+   L    R+K   +  +  L 
Sbjct: 3060 FRKHIKDI-KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLL 3115

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            I S R  D+G YT  A    G  VSTA + +E R
Sbjct: 3116 IPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3145



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            K++E + A FE  V   S+  +TV+W  + +++   +RI+   +     L I S R  D+
Sbjct: 3068 KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3124

Query: 1114 GVYTVVARNAAGEAQL 1129
            G YTVVA      A+L
Sbjct: 3125 GKYTVVAGGNVSTAKL 3140



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 4/94 (4%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPPK + ++    +  EG S   E  +    +P   V WF NG  L    +++ F +   
Sbjct: 4156 EPPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQ-FEEVNC 4212

Query: 3340 VI-LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
               L I     ++SG+Y+CVA N  G   + ++L
Sbjct: 4213 SHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDL 4246



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 7/135 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F +E      V E   + F   VE  G P   + W+ N        R+         
Sbjct: 5182 PPSF-IEPLTKRKVYENTTLGFIVEVE--GLPVPGVKWYRNKSLLEPDERIKMERVGNVC 5238

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE--L 3811
            +L+I  I   + GEY C A N  G A + A +    + + V+   LP  ++ + + E  L
Sbjct: 5239 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVV--ALPPPVTHQHVMEFDL 5296

Query: 3812 ERGRISDAPKEEPIV 3826
            E    S  P  + IV
Sbjct: 5297 EHTTSSRTPSPQEIV 5311



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 16/179 (8%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  P   T++ KDI +  E     +E ++   G   +  +W  NG  I+++ + +     
Sbjct: 2965 TVTPIMITSMLKDI-NAEEKDTITFEVTVNYEG---ISYKWLKNGVEIKSTDKCQMRTKK 3020

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L I      D+  Y+  A      A + V+   ++        F  HI++I+ L+ 
Sbjct: 3021 LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIE--------FRKHIKDIKVLEK 3072

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             + A FEC V    +PD+ ++W  + Q ++ + RIK   +     L I  T+  D+G+Y
Sbjct: 3073 -KRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKY 3127



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/95 (24%), Positives = 37/95 (38%)

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            ++ Q   P F++   +  V EG+         G P P +TW  + +PI  N    IH+  
Sbjct: 3937 KRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLE 3996

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              S L +      +     C   N  G+  T + L
Sbjct: 3997 NYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSML 4031



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 6/130 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++PL+        +N  L   +E  G P   V+W+ N   +    R K        +
Sbjct: 5183 PSFIEPLTKRKVY---ENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCS 5239

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI---ERSDIVTDTQNEQAIEQIQLLED 1293
            L+I +    + GEY   AVN +G A + A V ++   ER   +      Q + +  L   
Sbjct: 5240 LEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHT 5299

Query: 1294 AARRTKQVRE 1303
             + RT   +E
Sbjct: 5300 TSSRTPSPQE 5309



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 6/113 (5%)

Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALD 3756
            FT E++D +   +     F+C      +P +++ W+ +G     G +    +D     L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ---LPQGMSGE 3806
            I  I   DA +Y+C         TT   I   A  + V E Q   +P+  SGE
Sbjct: 2233 ILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGE 2285



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 2776 FISHLNNIVCKEGDNIH-FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            F   L ++V KE D +  FEC      +P +K++W+ +   +  G +Y+   D     L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTS 2860
            I      D+  Y+C     +   TT+
Sbjct: 2233 ILTIDTSDAEDYSCVLVEDENVKTTA 2258



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 8/84 (9%)

Query: 3433 REGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR---TFCDFGFVILEISPTYPED 3489
            REG++   E  ++   +P   V W+ NG  LK   +F+     C     I +++    +D
Sbjct: 4171 REGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNS---QD 4225

Query: 3490 SGEYLCRAYNNYGEAVTTASMKVQ 3513
            SG+Y C A NN G   + + + V+
Sbjct: 4226 SGKYKCVAENNSGAVESVSDLTVE 4249



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 7/144 (4%)

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            E  +P + E P   P F+  LT    + E     F   VE +  P   + W+ N   +  
Sbjct: 5172 EAIEPKDNEMP---PSFIEPLTK-RKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEP 5225

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
              R +        +L+I      + G YMC A N +GEA +   + +      ++    P
Sbjct: 5226 DERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPP 5285

Query: 2215 NGLEKIRQLEAQGHSTRIEVEEPK 2238
               + + + + + H+T      P+
Sbjct: 5286 VTHQHVMEFDLE-HTTSSRTPSPQ 5308



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F +P+   +V E   +     +  +  P   V+WY N   ++   R K        +L
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGL--PVPGVKWYRNKSLLEPDERIKMERVGNVCSL 5240

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +I      + G YMC A N +GEA + ++V +
Sbjct: 5241 EISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 11/147 (7%)

Query: 3670 ESIQKLEETLHKREEITIEDEKPN-----PPRFTVEIKDNID---VPEGGPVHFDCRVEP 3721
            E  ++ ++ L +  +ITI   KP+     P     +I + I    V +G   HF  RV  
Sbjct: 2044 ELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRV 2101

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
            VG P    +W+ NG       R++    +     L I  + A D+     +A N  G  +
Sbjct: 2102 VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETS 2161

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEK 3807
            + A +   AK+ I    +L   ++ EK
Sbjct: 2162 SHAFLLVQAKQLITFTQELQDVVAKEK 2188



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F K  +D  V E K   F+C V+  P   V W  +D++++     KI   E   H L+I
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQ-KEKYVHRLLI 3116

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAF----QCRLNVIEKEQVVAPK 492
             +  +SD+G  T VA  N S    F      R+  I+KE  V  K
Sbjct: 3117 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 3161



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 6/127 (4%)

Query: 1985 KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYA 2044
            K+A   EG  + LE  ++   +P   V W+ NG  ++Q  +F+         L I    +
Sbjct: 4166 KHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNS 4223

Query: 2045 EDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQ 2104
            +D+G Y C A N  G   + S + V+  +  Y +    + + +I    KY R + ++++ 
Sbjct: 4224 QDSGKYKCVAENNSGAVESVSDLTVEPVT--YRENSQFENIGEI--YGKYSRDQQLQDQG 4279

Query: 2105 PGQRPVF 2111
               R  F
Sbjct: 4280 ESVRAHF 4286



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 15/180 (8%)

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHF--ECRLIPVNDSSMRVEWFHNGKPL 3600
            GT +      ++  PP F    +   + EN++  F  E   +PV      V+W+ N   L
Sbjct: 5168 GTPNEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG----VKWYRNKSLL 5223

Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
                R+K         LEI  + + + G Y C A N  GEA     + +  ++  ++   
Sbjct: 5224 EPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALP 5283

Query: 3661 LPSHFKSGTESIQKLEETLHKR----EEITIEDE--KPNPPRFTVEIKDNIDVPEGGPVH 3714
             P   +   E    LE T   R    +EI +E E  + +   F  ++K  + VPE  P H
Sbjct: 5284 PPVTHQHVMEF--DLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVK-IVTVPEFTPDH 5340



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/97 (23%), Positives = 43/97 (44%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V+W ++   +E   RI         +L I ++   + G Y C A N IG+A + AN+ I+
Sbjct: 5214 VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKI 1039
             +++ +     P   + +   +     S RT    +I
Sbjct: 5274 PQEERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEI 5310



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I  L ++ C E  N+ FE  +  S    + + W F +K +   ++YK         L + 
Sbjct: 2536 IRGLRDLTCTETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVL 2592

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            +  ++D G YT  A    G   TSG L   G
Sbjct: 2593 NMMKDDEGKYTFYA----GENMTSGKLTVAG 2619



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 7/97 (7%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFG- 2698
            P FT  L ++  ++EG+ V    ++     P +   WF N   + TG R  +K+  D   
Sbjct: 3504 PSFTQKL-TFKYVLEGEPVVFTCRLIACPTPEMT--WFHNNRPIPTGLRRIIKAESDLHH 3560

Query: 2699 -LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
               +L I  +++ DSG Y   A N  G A STAS+ +
Sbjct: 3561 HSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 30/118 (25%), Positives = 45/118 (38%), Gaps = 5/118 (4%)

Query: 3019 TEGLEKIQNLEDSLRKEPGQQ---PDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPT 3075
            TE LE     +D + + P  +     D T  PP+            EG     E  +  +
Sbjct: 4126 TEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLI--S 4183

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            G+   V+ WF NG  ++ + + +         L I    + DSG Y C A N  G  E
Sbjct: 4184 GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVE 4241



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 1846 FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALD 1905
            F+ +L    ++ E  S   EC + P    N+  +WY N   L+S  +Y  ++  G   L 
Sbjct: 2269 FVKELQD-IEVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 1906 ILTVYGEDSGEYT 1918
            +  V  ED GEY+
Sbjct: 2325 VKDVTKEDQGEYS 2337



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            +   TV ES+   FEC V    +P  + EW R+GK LP  +  R+  D     L I    
Sbjct: 2626 LTDQTVAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATK 2682

Query: 3896 AEDSGEY 3902
             +D GEY
Sbjct: 2683 LDDIGEY 2689



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            ++E Q A +EC +    +P+ + EW  +GK L   +  R+ +D     L I     +D G
Sbjct: 2631 VAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIG 2687

Query: 1916 EYTCKAINNLGQA---VSSIRLNVQSKESIIRDSQ 1947
            EYT K   +   A   V ++++    K   + ++Q
Sbjct: 2688 EYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQ 2722



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EGQ    + +V   TD  LK+ W+     +      + T       L I     +D G Y
Sbjct: 3358 EGQPARFQCRVSG-TD--LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 3414

Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESLHPD 2748
            T  A+N +G+  STA++ +E    +L E +  +
Sbjct: 3415 TFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            P F   I++ E + +G S +F C       P   + WY+N  P+  +      S   + +
Sbjct: 3944 PSFLQEIESQE-VYEGDSCNFVCHFQGYPQPI--VTWYNNDMPIPRNQNFIIHSLENYSI 4000

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244
            L ++   + + G   C  +N+YG   T + +    K
Sbjct: 4001 LTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAK 4036



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 5/133 (3%)

Query: 1277 TDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQP 1336
            T+    +A+ Q Q+ +    R   +  DIT            +    EG ++ LEC +  
Sbjct: 4126 TEELEPKAMPQDQVTQSPKHRFVFL-SDITNEPPKMLQEMPKHARCREGDSIILECLIS- 4183

Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG--EA 1394
             G+    V WF NG  +K   +F+         L +  V  +DSG Y C A N  G  E+
Sbjct: 4184 -GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVES 4242

Query: 1395 VTSCALRVIAKKD 1407
            V+   +  +  ++
Sbjct: 4243 VSDLTVEPVTYRE 4255



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/88 (25%), Positives = 37/88 (42%), Gaps = 2/88 (2%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            +T + P   Q +      +EG +   +C +   G+P   V WF+N  L++ + +      
Sbjct: 4153 ITNEPPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEV 4210

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                 + I  V  +D G Y C A N  G
Sbjct: 4211 NCSHQLYIKDVNSQDSGKYKCVAENNSG 4238



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/59 (33%), Positives = 29/59 (49%)

Query: 3454 VEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            V+WY N   L+   R +         LEIS     + GEY+C A N  GEA + A++ +
Sbjct: 5214 VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++  +++G       R+   G PT  V+++R+   I+ S     + +    S
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+    ED G Y   A+N +G
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVG 183



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 765  QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824
            Q  Q   F + LQD+   ++   A FE +    S+P ++V+WYKDG  +    +     +
Sbjct: 2169 QAKQLITFTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSD 2225

Query: 825  FGYVSLNIMHLRAEDAGSYT 844
                 L+I+ +   DA  Y+
Sbjct: 2226 RKVHFLSILTIDTSDAEDYS 2245



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 7/143 (4%)

Query: 3559 EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILE 3618
            EF     D+ + E+ S   EC + P N   +  +W+HN   L +  +    +  G   L 
Sbjct: 2268 EFVKELQDIEVPESYSGELECIVSPEN---IEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 3619 IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEET 3678
            +  V + D G Y+       G+ T +CKL++K R   IL+         G     +++ +
Sbjct: 2325 VKDVTKEDQGEYSFVI---DGKKT-TCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS 2380

Query: 3679 LHKREEITIEDEKPNPPRFTVEI 3701
            L   E + ++D +   P   V I
Sbjct: 2381 LESVEGVWMKDGQEVQPSDRVHI 2403



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100
            + P+ L  +    +  EG S   E  +  +    +T  W+ NG  +    + Q       
Sbjct: 4156 EPPKMLQEMPKHARCREGDSIILECLISGEPQPVVT--WFQNGVLLKQNQKFQFEEVNCS 4213

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
              L I  V ++DSG Y  VA N +G  +  + +TVE
Sbjct: 4214 HQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVE 4249



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM-IHEGNNAVLLIGNTYE 4785
            +++  + EG    F  +++    P I W ++G  I     +QM   +   A L I     
Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLP 1356

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            ED G +T  A+   G    S KL V+
Sbjct: 1357 EDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 2122 KEGDR-AHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            KE D  A FEC     ++P + + W+ +G ++  G +YR   D     L IL     D+ 
Sbjct: 2186 KEKDTMATFECET---SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAE 2242

Query: 2181 TYMC 2184
             Y C
Sbjct: 2243 DYSC 2246



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            F + LQ+I+ + E  +   +C + P     ++ +W+ N+  ++ + + T T   G  ++T
Sbjct: 2269 FVKELQDIE-VPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 2438 ISHVRDEDEGVY 2449
            +  V  ED+G Y
Sbjct: 2325 VKDVTKEDQGEY 2336



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 910  EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
            EF+  IKD I + E   A FE     + +  + V+W+KD + ++ + RI          L
Sbjct: 3059 EFRKHIKD-IKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRL 3114

Query: 970  TIKSVTVHDAGHYTCRAYNAIGQA 993
             I S  + DAG YT  A   +  A
Sbjct: 3115 LIPSTRMSDAGKYTVVAGGNVSTA 3138



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/51 (31%), Positives = 24/51 (47%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            V+WY N   L+   R          +L+I +    + G Y C A+N +GEA
Sbjct: 5214 VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEA 5264



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            + + P F   +Q V  L EG +A FEA +     P+  V WF +G+ +           F
Sbjct: 2    TTQAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISF 58

Query: 3338 --GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              G   L I    + NSG Y   ATN  G+ ++ A L
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/123 (21%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            +++ ++ T  P FV R +S+  V +G  V  + ++  +    +K  ++++G  +     F
Sbjct: 94   ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDF 150

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEAGL 1552
            +   +    +L I +   EDSG Y+  A N VG    +  L  +   ++  + T+     
Sbjct: 151  QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVST 210

Query: 1553 EQI 1555
             QI
Sbjct: 211  AQI 213



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADT 1247
            + EG  +   C++   G P  ++ W+ +G+ +  G R++  +   G  +L I      D 
Sbjct: 1302 ILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDE 1359

Query: 1248 GEYTVRAVNHLGSA 1261
            G YT  A N  G+A
Sbjct: 1360 GIYTAFASNIKGNA 1373



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P  I Q   + K+ EG   Q +V++S      V W K+GQ +  S++  I+       L 
Sbjct: 2355 PIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLL 2413

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            + +  K D+G+Y+     P   + TSG ++V S
Sbjct: 2414 IEDMTKEDAGNYSFTI--PALGLSTSGRVSVYS 2444



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 8/119 (6%)

Query: 4700 SAGRVTVAAKLKVTQPDQADNL--PA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            S  R++   +L+ T   Q + L  P   L P+      EGQ A+F  ++  +  P   W 
Sbjct: 1433 SPARMSPGRRLEETDESQLERLYKPVFVLKPV-SFKCLEGQTARFDLKVVGRPMPETFWF 1491

Query: 4756 REGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +G  I      +++   +G  +++++  T   D+G +T  A   AG+   S  L V++
Sbjct: 1492 HDGQQIVNDYTHKVVIKEDGTQSLIIVPAT-PSDSGEWTVVAQNRAGRSSISVILTVEA 1549



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 774  RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIM 833
            +PL D   + E + A FE +   V++P  + EW +DG+ +  ++ I S  +     L I 
Sbjct: 2624 KPLTDQ-TVAESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIA 2679

Query: 834  HLRAEDAGSYTVR-AVNKLGEAISTASIRV 862
              + +D G YT + A +K    +   ++++
Sbjct: 2680 ATKLDDIGEYTYKVATSKTSAKLKVEAVKI 2709



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 2245 VTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDI 2304
            +T+      V E KTA FEC+V   + P++ ++   NG  ++ + +F I        L I
Sbjct: 2884 ITKTMKNIEVPETKTASFECEVSHFNVPSMWLK---NGVEIEMSEKFKIVVQGKLHQLII 2940

Query: 2305 QHCVPEDAGEYS 2316
             +   ED+ EY+
Sbjct: 2941 MNTSTEDSAEYT 2952


>AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform
            protein.
          Length = 5604

 Score =  294 bits (722), Expect = 4e-78
 Identities = 268/1028 (26%), Positives = 456/1028 (44%), Gaps = 98/1028 (9%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY---RTVYDMGF 3886
            P F+ ++K+  ++E  G + E +V    +P   I W +N  ++   H+Y   R     G 
Sbjct: 1556 PMFVEKLKNVNIKE--GSQLEMKVRATGNPNPDIVWLKNSDIIVP-HKYPKIRIEGTKGE 1612

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK---KLPDIILQNQVPRGMKRSE-- 3941
             +L I    ++DS  Y   A+N  G D T+  ++ +     P+   +  +PRG  R++  
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 3942 ALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVG 4001
            A  ++E    +Y  E +  E DLYD +K+Q P F  ++ S   L       FEC+L P+G
Sbjct: 1673 AAPELEPLHLRYGQEQW-EEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPIG 1730

Query: 4002 DPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
            DP M VEW  +GKPL   NR   I +FGY ++++G  Y  DSG   CRATN YG D T A
Sbjct: 1731 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1790

Query: 4062 VIKTTGKPGIVYDSQLPKHMKSIEKIREMEA-SWQVTPEQVVEESKARCPPVFVSLPDAV 4120
             +    +  +V +SQLP+  K +++I E+E  + +     V  + K +  P  V  P+ V
Sbjct: 1791 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1850

Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGKI 4180
             V EGE ARF CRVTG+P+P+V W LNG  I    R+++ YDG+++ DI   + YDTG++
Sbjct: 1851 RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEV 1910

Query: 4181 EVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYD-ETTQYQRTETELEK------ 4233
            +V              L++  R +D+R VL+ AP P  +    +  + + E++K      
Sbjct: 1911 KVTAENPEGVIEHKVKLEIQQR-EDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVD 1969

Query: 4234 TFEERQV--LQRQGVIDHRP------ELKPKVIKEPETEWQQSV------KRKKNEEYYN 4279
            T E ++V  L+R   I H        EL+ K  +  E  + +++       RKK+E Y  
Sbjct: 1970 TTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEE 2029

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQT---EEVTEQR 4336
             L++ ++E +     L E   +      K+T  T      +    +++     E +  Q 
Sbjct: 2030 LLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIE-LSPSMEAPKIFERIQSQT 2088

Query: 4337 VQKKVTQKPRI-----PDPSESTVHGKEVHVAKQKQTQKEVVGDKE---ITRKITSTETT 4388
            V +      R+     PDP E   +   V + +  +       D     + R +T+ ++ 
Sbjct: 2089 VGQGSDAHFRVRVVGKPDP-ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSA 2147

Query: 4389 EIEHKAQTQERVVEGP----VKPSKPPIFTKKMQPCRVFEHE-QARFEVEFDGEPLPLIK 4443
             I  KA              V+  +   FT+++Q     E +  A FE E   EP   +K
Sbjct: 2148 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECE-TSEPFVKVK 2206

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            WY++   +     +++H+      L I  +   D+  ++ V        K +A L+VE  
Sbjct: 2207 WYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE-DENVKTTAKLIVE-- 2263

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                 G +V   F    Q++ V       L+  +   + I+  W  N  +++ + +  I 
Sbjct: 2264 -----GAVV--EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTIT 2315

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623
               G   L + +   +D G+Y  V      +  C           K K KP+      P 
Sbjct: 2316 SRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTC-----------KLKMKPR------PI 2356

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
             I++ L D+ V EG  ++   K+  + +  V W K  + ++PS    +      + L I 
Sbjct: 2357 AILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIE 2415

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
            +   ED G+Y       A  ++ + ++ V   D       +TPL+D+ V EG  A  + +
Sbjct: 2416 DMTKEDAGNYSFTI--PALGLSTSGRVSVYSVD------VITPLKDVNVIEGTKAVLECK 2467

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            ++     +++W      I      Q I +G    L+I  T+  D G +        G+VE
Sbjct: 2468 VSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY----KLIVGRVE 2523

Query: 4804 TSAKLVVK 4811
            T+  L V+
Sbjct: 2524 TNCNLSVE 2531



 Score =  257 bits (630), Expect = 6e-67
 Identities = 163/511 (31%), Positives = 249/511 (48%), Gaps = 14/511 (2%)

Query: 377  RETEERIEIS-EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            R  EE  E   E+   P FV         EG+  RFD +V GRP PE  WF + +QI +D
Sbjct: 1441 RRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVND 1500

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
            Y HK+++ E G  +L+I   T SDSG  T VA+N++G ++    L V   E  V P FVE
Sbjct: 1501 YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560

Query: 496  RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN--PELRIHTDGGASTLDIPRA 553
            +   +N++EG  + +  RA G P P I W K+   I+P+  P++RI    G + L I   
Sbjct: 1561 KLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDST 1620

Query: 554  KASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXX 613
             + D+AWY  TA N AG   TR ++           +++L +PR T              
Sbjct: 1621 VSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPL 1680

Query: 614  YLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            +LR+ +         ++++    P F   L S+     G  HFE R+ P+GDPTM +EWL
Sbjct: 1681 HLRYGQEQWEEGDLYDKEK-QQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWL 1739

Query: 674  KNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             +G+ +EA++R   I  FGY SLD      +DSG  TCRA +  G   T A L V    +
Sbjct: 1740 HDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKS 1799

Query: 734  IERTSQHPETLQYIQQLEDYSKYQHQESI-----EEQTSQRPQFIRPLQDLGELQEGRNA 788
            +   SQ PE  + +Q++E+  +  H+ ++     +++  Q+P  +   + +  L EG  A
Sbjct: 1800 LVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVL-EGETA 1858

Query: 789  HFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAV 848
             F  ++T    P  +V WY +G+ I  S R    ++ G   L+I+  ++ D G   V A 
Sbjct: 1859 RFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAE 1915

Query: 849  NKLGEAISTASIRVAARSTVTADL-GIPEQR 878
            N  G       + +  R    + L   PE R
Sbjct: 1916 NPEGVIEHKVKLEIQQREDFRSVLRRAPEPR 1946



 Score =  188 bits (457), Expect = 6e-46
 Identities = 221/822 (26%), Positives = 347/822 (42%), Gaps = 106/822 (12%)

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTN-KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
            R  +  E +++   KP F+  LK  + K +EGQ+A F+ +V  +  +  T  W+ +G+QI
Sbjct: 1442 RLEETDESQLERLYKPVFV--LKPVSFKCLEGQTARFDLKVVGRP-MPETF-WFHDGQQI 1497

Query: 1087 TS--ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTS 1144
             +   +++    D G  +L I      DSG +TVVA+N AG + +S  +TVE        
Sbjct: 1498 VNDYTHKVVIKED-GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA------- 1549

Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPM 1204
                        +E    V+PM+    + K K V ++         EG  +  E ++   
Sbjct: 1550 ------------VEHQ--VKPMF----VEKLKNVNIK---------EGSQL--EMKVRAT 1580

Query: 1205 GDPTMRVEWFHNGRSVTVGS--RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAH 1262
            G+P   + W  N   +      + +     G  AL I    S D+  YT  A+N  G   
Sbjct: 1581 GNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDT 1640

Query: 1263 TSAIVRV--------IERSDIV---TDTQNEQAIEQIQLLEDAARRTKQVREDI---TVM 1308
            T   V V         ER  I+   T    E A  +++ L     + +    D+      
Sbjct: 1641 TRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQ 1700

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P F + L ++        H ECRL P+GD TM VEW  +GKP++  +R R   EF Y 
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1760

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            +LD    Y  DSG+ TC+ATN+ G   TS  L V  +K L+ ESQ P G + +Q +E+  
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELE 1820

Query: 1429 RYKKTDII-----DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN 1483
            R      +     D+    KP  V  P+ +  V+EG+   F C++        KV W+ N
Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLN 1877

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            GQ +    RFR  +D G   LDI+D  + D+G     A N  G  E   +L  +   D  
Sbjct: 1878 GQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF- 1935

Query: 1544 RSTQNEA--GLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKN-VEIKEGQRAHFERR 1600
            RS    A     +  V E          VD      P+ TT  K  V++K  +R   E+ 
Sbjct: 1936 RSVLRRAPEPRPEFHVHEPGKLQFEVQKVDR-----PVDTTETKEVVKLKRAERITHEK- 1989

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNF-GFVALDIMSCLPEDSGTYTCRAINALG 1659
             +P     L+ ++           R TE   +    A+++ S   ++S     R      
Sbjct: 1990 -VPEESEELRSKF----------KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-- 2036

Query: 1660 EAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKD 1719
                    ++H  K   L  + + AL    ++     ++    +     +AP     ++ 
Sbjct: 2037 -------ELLHWTKE--LTEEEKKALAEEGKI-TIPTFKPDKIELSPSMEAPKIFERIQS 2086

Query: 1720 IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPE 1778
              V +   AHF  R+  VG P    EW +NGV IE S+R+        V  L ++ V  E
Sbjct: 2087 QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2144

Query: 1779 DSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
            DS +   +AIN  GE  + + L VQ+K  +    + +  + K
Sbjct: 2145 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2186



 Score =  187 bits (455), Expect = 1e-45
 Identities = 178/649 (27%), Positives = 283/649 (43%), Gaps = 60/649 (9%)

Query: 3293 KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT-FHDFGIVILDILYCYEEN 3351
            +++EG    F  ++     P  K+ W+ +GK++ HG RY+  F   G   L I     E+
Sbjct: 1301 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358

Query: 3352 SGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTS 3411
             G Y   A+N       K N  C+ K  L ++   P G       + TLE   V R  + 
Sbjct: 1359 EGIYTAFASN------IKGNAICSGK--LYVEPAAPLGAP---TYIPTLEP--VSRIRSL 1405

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTP------TDDPNL----KVEWYWNGK 3461
                  ++P+   P + +   R        AR++P      TD+  L    K  +     
Sbjct: 1406 SPRSVSRSPIRMSP-ARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV 1464

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            S K         D   V   +  T+    G+ +    N+Y   V    +K  G +++I+ 
Sbjct: 1465 SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV---NDYTHKVV---IKEDGTQSLIIV 1518

Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEA-ESGNPPEFTTTPSDLILSENSSAHFECR 3580
               P              G S     LT EA E    P F     ++ + E S    + R
Sbjct: 1519 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVR 1578

Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGS--RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
                 + +  + W  N   ++     +++     G   L+I     +D+  YT  A N+ 
Sbjct: 1579 A--TGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1636

Query: 3639 GEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE----ETLHKR------EEITIE 3688
            G  T  CK+ V+  +    EP+       GT   +++     E LH R      EE  + 
Sbjct: 1637 GRDTTRCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1695

Query: 3689 D-EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            D EK   P F  ++  ++ +   GP HF+CR+ P+GDPTM ++W H+G+P    +R+  +
Sbjct: 1696 DKEKQQKPFFKKKLT-SLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMI 1754

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSG-E 3806
            N+FG+ +LD    Y+RD+G  TCRATNK+G+  T+A +    ++ +V ESQLP+G  G +
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQ 1814

Query: 3807 KIKELER----GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            +I+ELER    G ++    ++      P  +   +   V E E  RF CRV     PK  
Sbjct: 1815 RIEELERMAHEGALTGVTTDQK-EKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPK-- 1871

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            + WY NG+L+    R+R  YD G   LDI+   + D+GE    A N  G
Sbjct: 1872 VNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1919



 Score =  174 bits (424), Expect = 6e-42
 Identities = 156/534 (29%), Positives = 234/534 (43%), Gaps = 64/534 (11%)

Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488
            R ++TD        KP FV +P S +  +EGQ   F+ K+  V     +  WF +GQ + 
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFK-CLEGQTARFDLKV--VGRPMPETFWFHDGQQIV 1498

Query: 1489 IGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
              +  +  I + G  +L I+     DSG +T  A                         Q
Sbjct: 1499 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVA-------------------------Q 1533

Query: 1548 NEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEGQRAHFERRLIPVSD 1606
            N AG   I V+           V+ V  Q  P+    LKNV IKEG +   E ++    +
Sbjct: 1534 NRAGRSSISVILT---------VEAVEHQVKPMFVEKLKNVNIKEGSQ--LEMKVRATGN 1582

Query: 1607 ATLKVEWYHNNKPLKSGS--RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                + W  N+  +      +       G  AL I S + +DS  YT  AIN  G   T 
Sbjct: 1583 PNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1642

Query: 1665 GIAIVH--------SKKSIYLESQH---EGALPRLNQLE---DTSKYQRHSAQDEVITQA 1710
                V          +K I     +   E A P L  L       +++     D+   Q 
Sbjct: 1643 CKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQK 1702

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +  +R+     AHFE RL P+GDP + VEWL +G P+EA+NRL  +++FGY +L
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1762

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
            +       DSG  TCRA N+ G   TS+TL V+ + SL  ESQ     + +Q++E+  R 
Sbjct: 1763 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1822

Query: 1831 QRREDVE-VAVNQAPR---FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                 +  V  +Q  +    I     P ++ EG++A + CR+  YP P  +V WY NG++
Sbjct: 1823 AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQL 1880

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++   R+R   D G   LDI+     D+GE    A N  G     ++L +Q +E
Sbjct: 1881 IRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1933



 Score =  165 bits (402), Expect = 3e-39
 Identities = 136/477 (28%), Positives = 216/477 (45%), Gaps = 33/477 (6%)

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            EGQ A ++  ++  G       WF++G+ I  + +H++  +   G   L I+    +DSG
Sbjct: 1470 EGQTARFDLKVV--GRPMPETFWFHDGQQIVNDYTHKV-VIKEDGTQSLIIVPATPSDSG 1526

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             ++  A N+ G++ ISV L         KP F   ++N+  +K+G  +  E  V    +P
Sbjct: 1527 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNV-NIKEG--SQLEMKVRATGNP 1583

Query: 3180 DMKIEWYHNGQ---PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
            +  I W  N     P ++  +I+     G   L I  T + DS  Y   A NK G D TR
Sbjct: 1584 NPDIVWLKNSDIIVPHKY-PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1642

Query: 3237 ATINC---YGKGGVYLESLQPDSLAKIRELES-------LQGAQQQTPSTPSAEPPK--- 3283
              +N    + +     + + P    + +E+ +       L+  Q+Q       +  K   
Sbjct: 1643 CKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQK 1702

Query: 3284 -FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
             F  +     +L     AHFE RL P+ DP + VEW ++GK L   +R R  ++FG   L
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1762

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG--GLEKLQTL 3400
            D    Y  +SG   C ATNK G D T A L    +++L+ +SQLP G +G   +E+L+ +
Sbjct: 1763 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1822

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
                     T+ ++EK K  +   P      + EGE A F  R+T    P  KV WY NG
Sbjct: 1823 AHEGALTGVTTDQKEKQKPDIVLYP--EPVRVLEGETARFRCRVTGYPQP--KVNWYLNG 1878

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
            + ++   RFR   D G   L+I      D+GE    A N  G       +++Q + +
Sbjct: 1879 QLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1934



 Score =  162 bits (393), Expect = 3e-38
 Identities = 166/643 (25%), Positives = 270/643 (41%), Gaps = 50/643 (7%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSY--VS 2832
            +F+  L N+  KEG  +  E  V  + +P   I W  N+  +      K   + +    +
Sbjct: 1557 MFVEKLKNVNIKEGSQL--EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1614

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLE------- 2885
            L I  T  +DS  YT  A N  G  TT    RC  +  + F    P+ K  +        
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTT----RCKVNVEVEFAEPEPERKLIIPRGTYRAK 1670

Query: 2886 --AVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKN 2939
              A  + E   L  G+        Y K +   P   +     +L      H E ++ P  
Sbjct: 1671 EIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIG 1730

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            DP + +EW  +GK LE  +R ++ ++FG+ +LD    Y RDSGI TC+A NK G   TS+
Sbjct: 1731 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1790

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKE--PGQQPDDDTGRPPEFTTVFKDI 3057
            T+    + +L+E +Q P+G +GL++I+ LE    +    G   D    + P+   ++ + 
Sbjct: 1791 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEP 1849

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V + EG+ A +   +  TG     + W+ NG+ I  S R R  Y  G+  L+I+  K+ D
Sbjct: 1850 VRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYD 1906

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKS-------KGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            +G     A N  G  E  VKLE   +        +  +PR   H+     L+      FE
Sbjct: 1907 TGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQ------FE 1960

Query: 3171 CTVV--PVDDPDMK-IEWYHNGQPMRHSTRIKTVSDFGFVV---LDIAYTQNHDSGEYVC 3224
               V  PVD  + K +      + + H    +   +         +  Y +   + E   
Sbjct: 1961 VQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKS 2020

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            R  ++  E+  R T +        L   +  +LA+  ++        +   +PS E PK 
Sbjct: 2021 RKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKI 2080

Query: 3285 ITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR-YRTFHDFGIVILD 3343
              +IQ  T + +G  AHF  R+V   DP+   EW+ NG K+    R Y  + +  +  L 
Sbjct: 2081 FERIQSQT-VGQGSDAHFRVRVVGKPDPE--CEWYKNGVKIERSDRIYWYWPEDNVCELV 2137

Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQL 3386
            I     E+S      A N  G  S+ A L   +K+ +    +L
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQEL 2180



 Score =  157 bits (380), Expect = 1e-36
 Identities = 119/421 (28%), Positives = 194/421 (46%), Gaps = 33/421 (7%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV--QQGHRFKTTYDFGY 2034
            KP F + +KN  + EG  + ++   T   +P   + W  N   +   +  + +     G 
Sbjct: 1555 KPMFVEKLKNVNIKEGSQLEMKVRAT--GNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE 1612

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG------LYLDTLDEQRLKKI 2088
             AL I    ++D+  Y   A N  G   T   V V+ +          +      R K+I
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 2089 Q--ELE----KYERPK----PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPIND 2138
               ELE    +Y + +     + +++  Q+P F   LTSL  LK    AHFECR+ PI D
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLR-LKRFGPAHFECRLTPIGD 1731

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P + ++W H+G+ + A +R R  ++FGY +LD    Y+ DSG   C+ATNK G    + T
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791

Query: 2199 LKVAGHRNIILDTQHP---NGLEKIRQLEAQGHS---TRIEVEEPKISPPRFVTELRGTT 2252
            L V   ++++ ++Q P    GL++I +LE   H    T +  ++ +   P  V       
Sbjct: 1792 LIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVL-YPEPV 1850

Query: 2253 HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDA 2312
             V EG+TA F C+V     P  ++ +Y NG+ ++ + RF + +D G   LDI  C   D 
Sbjct: 1851 RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1907

Query: 2313 GEYSVKAINALGHCTSAISMTVTAKGSIISESQR-PEGLEKIRELESAE-PFKRPEIPEP 2370
            GE  V A N  G     + + +  +    S  +R PE   +    E  +  F+  ++  P
Sbjct: 1908 GEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRP 1967

Query: 2371 V 2371
            V
Sbjct: 1968 V 1968



 Score =  153 bits (370), Expect = 2e-35
 Identities = 172/672 (25%), Positives = 280/672 (41%), Gaps = 59/672 (8%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASS-- 817
            E++E Q   +P F+  L+++  ++EG  +  E ++    +P   + W K+   I      
Sbjct: 1548 EAVEHQV--KPMFVEKLKNVN-IKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYP 1602

Query: 818  RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA---ARSTVTADLGI 874
            +I      G  +L I    ++D+  YT  A+NK G   +   + V    A       L I
Sbjct: 1603 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1662

Query: 875  PE---QRRYI---EKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
            P    + + I   E                     E  QKP FK  +   + +K  G AH
Sbjct: 1663 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAH 1721

Query: 929  FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
            FE RL PIGD T+ VEWL DG+P+EA++R+     FGY +L        D+G  TCRA N
Sbjct: 1722 FECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1781

Query: 989  AIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKR-----TEEEVKITQKP 1043
              G   TSA L +  +K ++ ESQ P G + +Q +E+  R +          + K  QKP
Sbjct: 1782 KYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKP 1841

Query: 1044 RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVAL 1103
              +       +++EG++A F  RV         V WY NG+ I  + R +  +D G   L
Sbjct: 1842 DIV-LYPEPVRVLEGETARFRCRVTGYPQ--PKVNWYLNGQLIRKSKRFRVRYD-GIHYL 1897

Query: 1104 DIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFV 1163
            DI   ++ D+G   V A N  G  +    + ++ R   D  S+ R   E           
Sbjct: 1898 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE--DFRSVLRRAPEP---------- 1945

Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223
             P + + E  K +   VQ +  P   +E K +    R E +    +  E      S  + 
Sbjct: 1946 RPEFHVHEPGKLQ-FEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE------SEELR 1998

Query: 1224 SRFKTYYDFGFV-ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
            S+FK   + G+  A+  +   S    E     +             ++  +  +T+ + +
Sbjct: 1999 SKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-------ELLHWTKELTEEEKK 2051

Query: 1283 QAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTM 1342
               E+ ++     +  K   E    M+AP+    + +    +G++ H   R++ VG    
Sbjct: 2052 ALAEEGKITIPTFKPDK--IELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRVVGKPDP 2107

Query: 1343 RVEWFCNGKPIKTGHRFRPAYEFDYVA-LDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
              EW+ NG  I+   R    +  D V  L +  V  EDS     +A N  GE  +S A  
Sbjct: 2108 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE-TSSHAFL 2166

Query: 1402 VIAKKDLILESQ 1413
            ++  K LI  +Q
Sbjct: 2167 LVQAKQLITFTQ 2178



 Score =  152 bits (368), Expect = 3e-35
 Identities = 167/695 (24%), Positives = 296/695 (42%), Gaps = 69/695 (9%)

Query: 1939 KESIIRDSQH---ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPV 1995
            +E +I++ ++   ++ LE++  LE+D   K AV        +  F   IKN  + EG  V
Sbjct: 1251 EERLIKEIEYRIIKTTLEEL--LEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGV 1308

Query: 1996 HLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCKA 2054
                 ++    P  ++ WY +G+ ++ G R++  +   G  +L I     ED G Y   A
Sbjct: 1309 TFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA 1366

Query: 2055 TNAVGEAVTTSSVKVDAKSGL----YLDTLDEQRLKKIQELEKYERPK-PIEEEQPGQRP 2109
            +N  G A+ +  + V+  + L    Y+ TL+   + +I+ L      + PI        P
Sbjct: 1367 SNIKGNAICSGKLYVEPAAPLGAPTYIPTLEP--VSRIRSLSPRSVSRSPIRMSPARMSP 1424

Query: 2110 VFLT-ALTSLENLKEGDRAHF--ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
              ++ A  S   +  G R     E ++E +  P   +       K   G   R   D   
Sbjct: 1425 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV--SFKCLEGQTAR--FDLKV 1480

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLE 2224
            V   +  T+    G  +      + +  +   +K  G +++I+    P+  G   +    
Sbjct: 1481 VGRPMPETFWFHDGQQI------VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQN 1534

Query: 2225 AQGHST-----RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
              G S+      +E  E ++ P  FV +L+   ++ EG  +  E +V    +PN  I + 
Sbjct: 1535 RAGRSSISVILTVEAVEHQVKP-MFVEKLKNV-NIKEG--SQLEMKVRATGNPNPDIVWL 1590

Query: 2280 HNGKAL--QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             N   +      +  I    G  +L I   V +D+  Y+  AIN  G  T+   + V  +
Sbjct: 1591 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650

Query: 2338 GSIISESQR---PEGLEKIRELESAE-----------PFKRPEIPEPVTRQRPVFTQPLQ 2383
             +     ++   P G  + +E+ + E            ++  ++ +   +Q+P F + L 
Sbjct: 1651 FAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLT 1710

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++  ++    AHF+CRL P+GDPT+ VEW  + K +E ++R+   ++FGY S+       
Sbjct: 1711 SL-RLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYS 1769

Query: 2444 EDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE--- 2500
             D G+  CRA+N  G               +  E+Q PEG K +Q++E+  ER + E   
Sbjct: 1770 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEE-LERMAHEGAL 1828

Query: 2501 -----PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555
                   +E +KP    +   P  + EG+ A +  RV   G P  +  WY+NG  ++   
Sbjct: 1829 TGVTTDQKEKQKPDIV-LYPEPVRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSK 1885

Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            RFR  +D G   LDI    + D G     A N  G
Sbjct: 1886 RFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1919



 Score =  147 bits (356), Expect = 1e-33
 Identities = 112/386 (29%), Positives = 180/386 (46%), Gaps = 22/386 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGH-RYRTFHDFGI 3339
            P F+ ++++V  + EG     + R     +PD  + W  N   + PH + + R     G 
Sbjct: 1556 PMFVEKLKNVN-IKEGSQLEMKVRATGNPNPD--IVWLKNSDIIVPHKYPKIRIEGTKGE 1612

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDST--KANLKCTSKE-----NLILDSQLPRGMEG 3392
              L I     ++S  Y   A NK GRD+T  K N++    E      LI+     R  E 
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 3393 GLEKLQTLEDSMVRRK---DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
               +L+ L     + +       ++EK + P F   L+++   R G  AHFE RLTP  D
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGP-AHFECRLTPIGD 1731

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P + VEW  +GK L+A +R R   +FG+  L+    Y  DSG   CRA N YG   T+A+
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791

Query: 3510 MKVQGKRNIILESQLPKGMEGTIDKIAALE--GYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
            + V+ +++++ ESQLP+G +G + +I  LE   + G +  +T + +    P+    P  +
Sbjct: 1792 LIVKDEKSLVEESQLPEGRKG-LQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1850

Query: 3568 ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDA 3627
             + E  +A F CR+        +V W+ NG+ +    R +   D G   L+I      D 
Sbjct: 1851 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1907

Query: 3628 GLYTCKATNRHGEATVSCKLQVKGRQ 3653
            G     A N  G      KL+++ R+
Sbjct: 1908 GEVKVTAENPEGVIEHKVKLEIQQRE 1933



 Score =  146 bits (354), Expect = 2e-33
 Identities = 76/204 (37%), Positives = 109/204 (53%), Gaps = 4/204 (1%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP      Q V V SG+  R    ++G     + W K  + +    + K L +   YTLL
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            ++EA+P+D+  Y C A N  G A   A   V +P   +   P  +    PP II PL+D 
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP---EVVSPDQEMPVYPPAIITPLQDT 3354

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            + +EGQ   F C++ G  L  V WY  DK IKPS++F+M++  D Y L I+EA+PEDEG 
Sbjct: 3355 VTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 3413

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPD 4716
            Y  VA N+ G+V+  A L +  P+
Sbjct: 3414 YTFVASNAVGQVSSTANLSLEAPE 3437



 Score =  142 bits (344), Expect = 3e-32
 Identities = 113/391 (28%), Positives = 184/391 (47%), Gaps = 33/391 (8%)

Query: 1836 VEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY- 1893
            VE   +Q  P F+ +L     + EG  +  E ++    +PN  + W  N  ++   H+Y 
Sbjct: 1547 VEAVEHQVKPMFVEKLKN-VNIKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVP-HKYP 1602

Query: 1894 --RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ--------SKESII 1943
              R     G AAL I +   +DS  YT  AIN  G+  +  ++NV+         ++ II
Sbjct: 1603 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1662

Query: 1944 RDSQHESA------LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHL 1997
                + +       LE +       +++     D    +KP F K + +  +    P H 
Sbjct: 1663 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHF 1722

Query: 1998 EATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNA 2057
            E  LTP+ DPTM VEW  +G+P++  +R +   +FGY +LD   AY+ D+G   C+ATN 
Sbjct: 1723 ECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNK 1782

Query: 2058 VGEAVTTSSVKV-DAKSGLYLDTLDEQR--LKKIQELEKYERPKPI----EEEQPGQRPV 2110
             G   T++++ V D KS +    L E R  L++I+ELE+      +     +++  Q+P 
Sbjct: 1783 YGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPD 1842

Query: 2111 FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALD 2170
             +     +  L EG+ A F CRV     P   ++W+ NGQ IR   R+R  +D G   LD
Sbjct: 1843 IVLYPEPVRVL-EGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLD 1898

Query: 2171 ILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            I+   + D+G     A N  G   +   L++
Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929



 Score =  139 bits (337), Expect = 2e-31
 Identities = 118/441 (26%), Positives = 191/441 (43%), Gaps = 29/441 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN--RLTTMHDFGYV 1768
            P+F   +K++ + E   +  E ++   G+P   + WL+N   I      ++      G  
Sbjct: 1556 PMFVEKLKNVNIKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1613

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK-ASLQLESQ----------HESA 1817
            AL +     +DS  YT  AIN+ G   T   + V+ + A  + E +           E A
Sbjct: 1614 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1673

Query: 1818 LQKIQQLE---DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874
              +++ L       +++  +  +    Q P F  +L    +L     AH+ECR+ P  DP
Sbjct: 1674 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPIGDP 1732

Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934
             M VEW  +GK L++ +R R  N+FG+ +LD    Y  DSG  TC+A N  G   +S  L
Sbjct: 1733 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1792

Query: 1935 NVQSKESIIRDSQHESALEKIQYLEDDSRYKR-----AVQDDSFVVEKPQFGKPIKNAEV 1989
             V+ ++S++ +SQ     + +Q +E+  R         V  D    +KP      +   V
Sbjct: 1793 IVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1852

Query: 1990 TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGT 2049
             EG        +T    P  +V WY NG+ +++  RF+  YD G   LDI+   + DTG 
Sbjct: 1853 LEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGE 1909

Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRP 2109
                A N   E V    VK++ +      ++  +  +   E   +E  K   E Q   RP
Sbjct: 1910 VKVTAENP--EGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRP 1967

Query: 2110 VFLTALTSLENLKEGDRAHFE 2130
            V  T    +  LK  +R   E
Sbjct: 1968 VDTTETKEVVKLKRAERITHE 1988



 Score =  136 bits (330), Expect = 1e-30
 Identities = 116/410 (28%), Positives = 186/410 (45%), Gaps = 44/410 (10%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F K ++  +V E ++A FE E   EP   ++W +++  ++ +   +I        L+I  
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPS 3118

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              + D+  +  VA     TAK    L VE +  + R            + V V   Q   
Sbjct: 3119 TRMSDAGKYTVVAGGNVSTAK----LFVEGRDVRIRS---------IKKEVQVIEKQRAV 3165

Query: 4533 LDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            ++ +V     +D +W K+G ++  Q   R+K + E   + + I E    D+G+Y  VA  
Sbjct: 3166 VEFEVN-EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA-- 3222

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
              G  R      V+ P               PP++++ L+   V  G+   F   I G+P
Sbjct: 3223 --GRNRSSVTLYVNAPE--------------PPQVLQELQPVTVQSGKPARFCAVISGRP 3266

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P + WYK ++L+      +      EYTL + EAFPED   Y C A N  G  T +A L
Sbjct: 3267 QPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASL 3326

Query: 4711 -----KVTQPDQADNL--PA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                 +V  PDQ   +  PA +TPL+D V  EGQPA+F+ ++ S     + W  +   I 
Sbjct: 3327 SVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIK 3385

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  F+M    +   L I   Y ED GT+T  A+ A GQV ++A L +++
Sbjct: 3386 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435



 Score =  134 bits (324), Expect = 7e-30
 Identities = 128/502 (25%), Positives = 219/502 (43%), Gaps = 32/502 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++  K     HFEC + P  DPT+ +EW  + KPL +  R +  ++F Y SLD 
Sbjct: 1705 FKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDY 1764

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE-AR 2894
               Y  DSGI TC+ATN  G+  TS +L    +K++  ++Q P+G+ GL+ +E+ E  A 
Sbjct: 1765 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1824

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
                   +    E  KP+ I+      +++EG+      +V     P  K+ WY NG+++
Sbjct: 1825 EGALTGVTTDQKEKQKPD-IVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQLI 1881

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN---LIE 3011
             +  RF++  D G   LD+VD    D+G     A N  G       +    +++   ++ 
Sbjct: 1882 RKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLR 1940

Query: 3012 RTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQ-IAHY-- 3068
            R   P+    + +   L+  ++K           RP + TT  K++V +   + I H   
Sbjct: 1941 RAPEPRPEFHVHEPGKLQFEVQK---------VDRPVD-TTETKEVVKLKRAERITHEKV 1990

Query: 3069 --EASLIPTGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMV--VLEILGTKTTDSGTYSC 3123
              E+  + +  +    E +Y   T +E   R +      ++    + L   T +      
Sbjct: 1991 PEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEK 2050

Query: 3124 RATNKWGQAEI-SVKLECVDKSKGQK-PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181
            +A  + G+  I + K + ++ S   + P+    IQ+ + +  G  AHF   VV   DP+ 
Sbjct: 2051 KALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC 2109

Query: 3182 KIEWYHNGQPMRHSTRIKTV-SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
              EWY NG  +  S RI     +     L I      DS   + +A N  GE  + A + 
Sbjct: 2110 --EWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLL 2167

Query: 3241 CYGKGGVYLESLQPDSLAKIRE 3262
               K  +       D +AK ++
Sbjct: 2168 VQAKQLITFTQELQDVVAKEKD 2189



 Score =  128 bits (309), Expect = 5e-28
 Identities = 102/387 (26%), Positives = 167/387 (43%), Gaps = 25/387 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF---RFGY 693
            P F+  LK+V   EG ++  E ++   G+P   I WLKN   I    ++  I      G 
Sbjct: 1556 PMFVEKLKNVNIKEGSQL--EMKVRATGNPNPDIVWLKNSDII-VPHKYPKIRIEGTKGE 1612

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT--------------PRATIERTSQ 739
             +L + S   QDS  YT  A++  G   T+  ++V               PR T      
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 740  HPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSD 799
                L+ +       +++  +  +++  Q+P F + L  L  L+    AHFE +LTP+ D
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPIGD 1731

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PTM VEW  DG+P+ A++R+  I  FGY SL+     + D+G  T RA NK G   ++A+
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791

Query: 860  IRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQI 919
            + V    ++  +  +PE R+ +++                    +  QKP+      + +
Sbjct: 1792 LIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEPV 1850

Query: 920  SIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDA 979
             + EG  A F  R+   G    +V W  +G+ +  S R    ++ G   L I     +D 
Sbjct: 1851 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1907

Query: 980  GHYTCRAYNAIGQATTSANLTIVTKKD 1006
            G     A N  G       L I  ++D
Sbjct: 1908 GEVKVTAENPEGVIEHKVKLEIQQRED 1934



 Score =  126 bits (305), Expect = 1e-27
 Identities = 85/307 (27%), Positives = 136/307 (44%), Gaps = 16/307 (5%)

Query: 66   PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            PGEP+ P F       +  +GG+  F  ++ GNP P V W +   PL    +Y + YN+Q
Sbjct: 1076 PGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1135

Query: 126  TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR----- 180
            TG+  L+I      D GEYT   RN++GE   S  +  E              Y+     
Sbjct: 1136 TGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1195

Query: 181  -----HVSETVEHKAYG--TQGYTTEQSRQTQKVAYTNGTDHSSTDD--FKVDTFEYRLL 231
                  V ET     Y    + Y  EQ+   +K+A       +  +D  F + +FE RL+
Sbjct: 1196 FVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1255

Query: 232  REVSFR-ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLS 290
            +E+ +R    T   + E D +    +D S           + +N ++ EG    F  ++S
Sbjct: 1256 KEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMS 1315

Query: 291  GNPRPRVTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            G P P++ W+K+G+R+ +  ++++        +LR+      D G YT  A N  G  + 
Sbjct: 1316 GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAIC 1375

Query: 350  SGYLAVE 356
            SG L VE
Sbjct: 1376 SGKLYVE 1382



 Score =  118 bits (284), Expect = 5e-25
 Identities = 113/500 (22%), Positives = 208/500 (41%), Gaps = 31/500 (6%)

Query: 4247 IDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIK-ESRL-RESTHQYAI 4304
            +DH  E    +++ P     Q  +  ++EE     Q + +E++ + E R+ +E+  + ++
Sbjct: 3762 VDHSAE---SIVQNPHALSNQMDQNIESEELPTSFQTIVDEEIFQTEIRMSQEALVKESL 3818

Query: 4305 PGDK------VTSNTVAKSMAQRYEDNL---DQTEEVTEQRVQKKVTQKP----RIPDPS 4351
            P D       V  NT A+   +    N    + +  +T    +++V + P    +   P 
Sbjct: 3819 PKDHLYGEILVNENTQARGQLEEIMANTTIGESSTYITNVCEKEEVYETPENVSQAITPH 3878

Query: 4352 ESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE---RVVEGPVK-- 4406
             S   G  V+V + ++   E +   ++     S  T   E K + +E   R  E   +  
Sbjct: 3879 ASESFGTLVNVEESEEIASERIKKDDLRELQLSASTRIDEFKTEQKEENMRFFENSFRKR 3938

Query: 4407 PSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            P + PP F ++++   V+E +   F   F G P P++ WY  + PI  + +F IH+    
Sbjct: 3939 PQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENY 3998

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG-RGGIVP--PSFTLTAQN 4522
            SIL +  V  ++      V  N+ GT K ++ L V+ K++   +   VP    +    + 
Sbjct: 3999 SILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYLDEEEE 4058

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP-QDS 4581
            + +   Q       ++     +++ LK    V P    ++L       +      P QD 
Sbjct: 4059 LALVFDQAKGAHPSMSQEGQTNLHLLKTNPPVPPSGDTELLSFPVEIQVTAATPIPEQDK 4118

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL-KDKIVAEGQAI 4640
               E              + V   P  K +    +   N PP++++ + K     EG +I
Sbjct: 4119 ESKEVFQTEELEPKAMPQDQVTQSP--KHRFVFLSDITNEPPKMLQEMPKHARCREGDSI 4176

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
               C I G+P P V W++   L+K ++ FQ       + L I +   +D G YKCVA N+
Sbjct: 4177 ILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENN 4236

Query: 4701 AGRVTVAAKLKVTQPDQADN 4720
            +G V   + L V      +N
Sbjct: 4237 SGAVESVSDLTVEPVTYREN 4256



 Score =  113 bits (271), Expect = 2e-23
 Identities = 143/649 (22%), Positives = 258/649 (39%), Gaps = 54/649 (8%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH-DFGYVALDILYTYAEDSGT 2181
            EG    F C++     P +   W+ +G++I+ G RY+      G  +L I     ED G 
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIA--WYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361

Query: 2182 YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLEAQGHS-TRIEVEEPK 2238
            Y   A+N  G A+ +  L V     +   T  P    + +IR L  +  S + I +   +
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPAR 1421

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHF--ECQVEPVHDPNLRIEFYHNGKALQS-AARFHITF 2295
            +SP R          +  G+      E Q+E ++ P   ++   + K L+   ARF +  
Sbjct: 1422 MSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV-SFKCLEGQTARFDLKV 1480

Query: 2296 DFGYVSLDIQ-HCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQRPEGLEK 2352
                +      H   +   +Y+ K +       S I +  T    G     +Q   G   
Sbjct: 1481 VGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSS 1540

Query: 2353 IRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEW 2412
            I  + + E  +         + +P+F + L+N+ NI+EG  +  + ++   G+P   + W
Sbjct: 1541 ISVILTVEAVEH--------QVKPMFVEKLKNV-NIKEG--SQLEMKVRATGNPNPDIVW 1589

Query: 2413 FRNEKLIEDSS--RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXX 2470
             +N  +I      +I      G  ++ I     +D   Y   A N  G            
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649

Query: 2471 XXXIQLETQH----PEGMKKIQKLEQP-----HERRSEEP-------DREFE-KPIFTQV 2513
                + E +     P G  + +++  P     H R  +E        D+E + KP F + 
Sbjct: 1650 EFA-EPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1708

Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSV 2573
            LT    L     AH+E R+ P+GDP++  EW  +G  L+  +R R  ++FG+ +LD    
Sbjct: 1709 LTS-LRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVA 1767

Query: 2574 VANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPE-- 2631
             + D+G+  C+A N+ G               +++++  PE  + +Q  E       E  
Sbjct: 1768 YSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGA 1827

Query: 2632 ---MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
               +  D   +Q P    + +   +++EG+      +V     P  K+ W+ NG  +   
Sbjct: 1828 LTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKS 1884

Query: 2689 ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             R +  +D G+  L I   ++ D+G     A N  G       ++I+ R
Sbjct: 1885 KRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1932



 Score =  111 bits (266), Expect = 8e-23
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 11/228 (4%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS--PDFQIHTFSTK 4465
            ++ P FT+ +Q   V E   A FE    G P+P + W+R+   I  S  P  QI     +
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            + L I  V   +S  ++  A N  G A  +A L+V+ +         PP+F    Q++ V
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET-------APPNFVQRLQSMTV 115

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  VRL  +VTG     V + ++G ++Q  +  +I +E   Y+LLI EAYP+DSG Y 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
              A NS G A   AE +V     ++ P  +TK   +  +I E  + +I
Sbjct: 176  VNATNSVGRATSTAELLVQ--GEEEVPAKKTKTIVSTAQISESRQTRI 221



 Score =  109 bits (261), Expect = 3e-22
 Identities = 69/234 (29%), Positives = 108/234 (46%), Gaps = 14/234 (5%)

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            A ++  R   A+ S    +EE        +  P F L   +     GQ  R D KV G  
Sbjct: 1425 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRP 1484

Query: 4542 PIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
              + +W  +G+++  D  +K+ ++EDGT +L+I+ A P DSG++  VA N AG  R    
Sbjct: 1485 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG--RSSIS 1542

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             ++++ A + + KP           +E LK+  + EG  +E   +  G P P + W K  
Sbjct: 1543 VILTVEAVEHQVKPM---------FVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNS 1593

Query: 4661 KLIKPSKY--FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +I P KY   ++  T  E  L+I     +D   Y   A N AGR T   K+ V
Sbjct: 1594 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647



 Score =  107 bits (256), Expect = 1e-21
 Identities = 179/750 (23%), Positives = 286/750 (38%), Gaps = 90/750 (12%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYING--VELKMGSRFRTTHDFG 2564
            KP+F + L   + + EG  +  E +V   G+P+    W  N   +      + R     G
Sbjct: 1555 KPMFVEKLKNVN-IKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKG 1611

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXX--------IIDQAM-RPES 2615
               L I+S V+ D+  Y   AIN+AG                       II +   R + 
Sbjct: 1612 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKE 1671

Query: 2616 WEQIQLKEAAMNKVPEMF-----VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRT 2670
                +L+   +    E +      D   QQ P F   L S  +L      + E ++ P  
Sbjct: 1672 IAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPIG 1730

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DP + +EW  +G  L    RL+   +FG  +L      + DSGI TC+ATN  G   ++A
Sbjct: 1731 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1790

Query: 2731 SIKIEDRHWLLGESLHPD---SLDRIGALXXXXXXXXXXXXXXXXXXV----FISHLNNI 2783
            ++ ++D   L+ ES  P+    L RI  L                        + +   +
Sbjct: 1791 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1850

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
               EG+   F C V     P  K+ W+ N + +    R++  +D  +  LDI      D+
Sbjct: 1851 RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYDGIHY-LDIVDCKSYDT 1907

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
            G     A N +G                    +H   K  LE ++Q E+ R    R P  
Sbjct: 1908 GEVKVTAENPEGV------------------IEH---KVKLE-IQQREDFRSVLRRAPE- 1944

Query: 2904 PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLK-IEWYFNGKVLEQG----S 2958
                 P+PE+ +    + Q    +V       E K    LK  E   + KV E+     S
Sbjct: 1945 -----PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRS 1999

Query: 2959 RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKG 3018
            +FK  ++ G+   + +   E  S         K+ E++    +   +KD L+  T+  + 
Sbjct: 2000 KFKRRTEEGY--YEAITAVELKS--------RKKDESY--EELLRKTKDELLHWTK--EL 2045

Query: 3019 TEGLEKIQNLEDSLRKEPGQQPDDDTGRPP-EFTTVFKDIVD--ISEGQIAHYEASLIPT 3075
            TE  EK    E+     P  +PD     P  E   +F+ I    + +G  AH+   ++  
Sbjct: 2046 TEE-EKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVV-- 2102

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAEI 3134
            G      EW+ NG  IE S RI   +    V  L I      DS +   +A N  G+   
Sbjct: 2103 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2162

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L    K   Q   FT  +Q++   +    A FEC      +P +K++WY +G  +  
Sbjct: 2163 HAFLLVQAK---QLITFTQELQDVVAKEKDTMATFEC---ETSEPFVKVKWYKDGMEVHE 2216

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              + +  SD     L I      D+ +Y C
Sbjct: 2217 GDKYRMHSDRKVHFLSILTIDTSDAEDYSC 2246



 Score =  105 bits (251), Expect = 5e-21
 Identities = 110/421 (26%), Positives = 164/421 (38%), Gaps = 28/421 (6%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129
            PP F +     +  +     F  ++ G P P V W R K+ L    +  M   E+ G+V 
Sbjct: 5182 PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKM---ERVGNVC 5238

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEA--ICSVYIQPEGXXXXXXXXXXXXXYRHVSE--- 184
            SL I  I  G+ GEY C A N  GEA    +V I P+              ++HV E   
Sbjct: 5239 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQ--EERVVALPPPVTHQHVMEFDL 5296

Query: 185  --TVEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
              T   +    Q    E     + V  +       +  +F  D     +  +V     + 
Sbjct: 5297 EHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPDHKSMIVSLDVLPFNFVD 5356

Query: 242  KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
                         +ID  +  + PP+      + K+ E +DA F+  + G P P V W+K
Sbjct: 5357 PNMDSREGEDKELKIDLEVFEM-PPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYK 5415

Query: 302  NGQRLINSN-KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
                +   N K+ I       TL++RN   SDS  Y   A N  G  +  G+L +     
Sbjct: 5416 EYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEI 5475

Query: 361  SYVQDQRSQYITDTQQRE-------TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
              V  ++S+    +   E       T+   E       P+F+K   D     G    F C
Sbjct: 5476 FAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC 5535

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN--HALMITNVTLSDSGVVTCVARNKS 471
             V G P P V W+ + + ++     +  V ESG   H L IT++  SD G   CVA NKS
Sbjct: 5536 LVRGSPRPTVYWYKDGKLVQ---GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKS 5592

Query: 472  G 472
            G
Sbjct: 5593 G 5593



 Score =  104 bits (249), Expect = 9e-21
 Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 19/258 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN--KILEEDGTYTL 4571
            P+FT   Q+V V  G     +  ++G    +V W ++G+ +        +I   DG   L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      +SG+Y   A N +G+A   AE +V             KA  APP  ++ L+ 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------KAETAPPNFVQRLQS 112

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V +G  +    ++ G P P V++Y+    I+ S  FQ+S+  D Y+L I+EA+PED G
Sbjct: 113  MTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK-- 4749
             Y   A NS GR T  A+L V   ++       T +    + E +  + + +I +     
Sbjct: 173  TYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDAR 232

Query: 4750 --PTIQWLREGALIPETP 4765
               T++ + +GA   + P
Sbjct: 233  SIATVEMVIDGAAGQQLP 250



 Score =  102 bits (244), Expect = 4e-20
 Identities = 70/234 (29%), Positives = 108/234 (46%), Gaps = 16/234 (6%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV+PP +    +N  + EG     +  +SG P P VTW++   ++ +S   +I       
Sbjct: 939  PVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIA 998

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE----------SPTESYVQDQR---- 367
             L +R     DSG +T  A N  G + TS YLAV+          + TE +  +++    
Sbjct: 999  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1058

Query: 368  SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            S+ +  T    TEE+    E A AP F+     + + EG    F C+V G P P V W  
Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPA-APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1117

Query: 428  NDRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            +   +   Y +K+  N ++G   L+I+     D+G  T V RNK GET+    L
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score =  100 bits (240), Expect = 1e-19
 Identities = 76/284 (26%), Positives = 123/284 (43%), Gaps = 8/284 (2%)

Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITS----T 4385
            +EV     Q+ V +     D  ++  +   + +  Q Q + + V ++ I R   S    +
Sbjct: 3154 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3213

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445
            +  E    A      V   V   +PP   +++QP  V   + ARF     G P P I WY
Sbjct: 3214 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3273

Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR- 4504
            +E   +      +      +  L++ + F ED+AV+   A+N  G A  SA+L VE    
Sbjct: 3274 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3333

Query: 4505 --RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                    + PP+     Q+   + GQ  R   +V+GT  + V W    KK++P    ++
Sbjct: 3334 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRM 3392

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
             + + TY L I EAYP+D G Y  VA N+ G+    A   +  P
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 57/193 (29%), Positives = 97/193 (50%), Gaps = 4/193 (2%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYTL 4680
            P   +PL+  +V EG    F   I G P+P V W++  ++I  S     Q+S +     L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             I      + G Y   A N +G+ T  A+L V       N   +  L+ + V +G   + 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNF--VQRLQSMTVRQGSQVRL 123

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + ++T    P +++ R+GA I  + DFQ+  EG+   LLI   Y ED+GT++  AT + G
Sbjct: 124  QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183

Query: 4801 QVETSAKLVVKSK 4813
            +  ++A+L+V+ +
Sbjct: 184  RATSTAELLVQGE 196



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 60/189 (31%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F +  Q   V EG    F+  ++G P PEV+WF + + I       + ++ S   A 
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I  VT ++SG  +  A N SG+      L V  K +   P FV+R  ++ VR+G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV--KAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L  R  G PTP + + +DG  I  + + +I  +G   +L I  A   D+  Y   A N  
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182

Query: 570 GSTATRARL 578
           G   + A L
Sbjct: 183 GRATSTAEL 191



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 114/474 (24%), Positives = 192/474 (40%), Gaps = 66/474 (13%)

Query: 3643 VSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETL---HKREEITIEDEKPNPPRFTV 3699
            +    QV+ R   ++E ++   F S T      E T      R  +T+    P PP+   
Sbjct: 3184 IEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQ 3243

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
            E++  + V  G P  F C V   G P  +I W+   +  +TG +   L+D     L +  
Sbjct: 3244 ELQP-VTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE 3300

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
             +  DA  YTC A N +G ATT+A           L  ++P+ +S +             
Sbjct: 3301 AFPEDAAVYTCEAKNDYGVATTSAS----------LSVEVPEVVSPD------------- 3337

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
             +E P+   PP  IT ++     E +  RF+CRV   +   L++ WY   K +     +R
Sbjct: 3338 -QEMPVY--PPAIITPLQDTVTSEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFR 3391

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR--GM 3937
                     L+I   Y ED G Y   A N  G+  + A +S  + P+ IL  ++ +   M
Sbjct: 3392 MTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL-EAPESILHERIEQEIEM 3450

Query: 3938 KRSEALTQMEAT-IKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTS------------ 3984
            +  E  ++ E+   ++ T + +   +D+ D       R+ ++I S +S            
Sbjct: 3451 EMKELFSEGESEHSERDTRDAFSDSEDI-DHKSMAAKRYASRISSTSSWPEYFKPSFTQK 3509

Query: 3985 -----LVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR--FTPIYDFGY--VAMNF 4035
                 ++E E   F C+L  +  P  ++ WF N +P+    R       D  +   ++  
Sbjct: 3510 LTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEI 3567

Query: 4036 GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE 4089
              V   DSG Y   A N  G  E+ A +    K     D +  + +K  E+  E
Sbjct: 3568 KRVQDRDSGSYRLLAINSEGSAESTASLLVIQKG---QDEKYLEFLKRAERTHE 3618



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 105/404 (25%), Positives = 168/404 (41%), Gaps = 44/404 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P + T  ++     E +   FEV  + E +   KW +    IK++   Q+ T      L 
Sbjct: 2968 PIMITSMLKDINAEEKDTITFEVTVNYEGISY-KWLKNGVEIKSTDKCQMRTKKLTHSLN 3026

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            IR V   D+A +  VA    G A  +A L VE +  + R  I         +++ V   +
Sbjct: 3027 IRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHI---------KDIKVLEKK 3073

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
                + +V+    I V W+K+ +++Q   R KI +E   + LLI      D+GKY  VA 
Sbjct: 3074 RAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAG 3132

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
             +   A+   E        +D    + ++     ++IE  K + V     +EF    V +
Sbjct: 3133 GNVSTAKLFVE-------GRD---VRIRSIKKEVQVIE--KQRAV-----VEFE---VNE 3172

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                  WYK    I      +     +   + + ISE    D G+Y  V    AGR   +
Sbjct: 3173 DDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV----AGRNRSS 3228

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              L V  P+    L  L P   + V  G+PA+F   I+ + +P I W +E  L+      
Sbjct: 3229 VTLYVNAPEPPQVLQELQP---VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3285

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + +H+G    LL+   + ED   +TC A    G   TSA L V+
Sbjct: 3286 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 71/236 (30%), Positives = 110/236 (46%), Gaps = 10/236 (4%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMH 1763
            EV    P F MP+ D ++ EN  A F+  +I +  P+  V+W +  + IE  N +     
Sbjct: 5374 EVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISE 5431

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-QSKASLQLESQHESALQKI- 1821
            + G   L ++ V   DS TY CRA+N +GEA+    L +  S+    +  + +  L  + 
Sbjct: 5432 EKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLM 5491

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            ++L   S Y         V   PRFI  ++       G +A+++C +   P P   V WY
Sbjct: 5492 EELVLKSNYTDSFFEFQVVEGPPRFIKGISD-CYAPIGTAAYFQCLVRGSPRPT--VYWY 5548

Query: 1882 FNGKVLQSGHRYRTSND-FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +GK++Q G R+       GF  L I ++   D GEY C A N  G A S   L +
Sbjct: 5549 KDGKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 92/396 (23%), Positives = 164/396 (41%), Gaps = 64/396 (16%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E PQ  + ++   V  G P    A ++    P  ++ WY   + +  G + K  +D    
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L ++ A+ ED   Y C+A N  G A T++S+ V                    E+ +  
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------------------EVPEVV 3334

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
             P   ++E P   P  +T L       EG  A F+CRV   +   L + W+   +KI+  
Sbjct: 3335 SP---DQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPS 3387

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN 2215
              +R T       L+I   Y ED GTY   A+N +G+  +T  L +    +I+ +     
Sbjct: 3388 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447

Query: 2216 GLEKIRQLEAQG---HSTR---------IEVEEPKISPPRFVTELRGTT----------- 2252
               ++++L ++G   HS R          +++   ++  R+ + +  T+           
Sbjct: 3448 IEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFT 3507

Query: 2253 ------HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY----VSL 2302
                  +V EG+   F C++  +  P   + ++HN + + +  R  I  +        SL
Sbjct: 3508 QKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSL 3565

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKG 2338
            +I+     D+G Y + AIN+ G   S  S+ V  KG
Sbjct: 3566 EIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKG 3601



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/224 (29%), Positives = 98/224 (43%), Gaps = 12/224 (5%)

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDF 4457
            E   E  ++    P+F  K    +  E + ARF+++  G P+P   W+ +   I N    
Sbjct: 1444 EETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTH 1503

Query: 4458 Q--IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
            +  I    T+S++I+      DS  +  VA+NR G +  S  L VE    Q     V P 
Sbjct: 1504 KVVIKEDGTQSLIIV-PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQ-----VKPM 1557

Query: 4516 FTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLI 4573
            F    +NVN+  G  + +  + TG    D+ WLKN   + P    KI  E   G   L I
Sbjct: 1558 FVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKI 1617

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                 QDS  Y   AIN AG  R    C V++     +P+P+ K
Sbjct: 1618 DSTVSQDSAWYTATAINKAG--RDTTRCKVNVEVEFAEPEPERK 1659



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 105/467 (22%), Positives = 175/467 (37%), Gaps = 46/467 (9%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   +     K+ E     F V++ G P P V W++N   L    + ++    N  +L 
Sbjct: 5182 PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLE 5241

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            + N QK + G Y   A N  G   +   + +  P E  V          T Q   E  +E
Sbjct: 5242 ISNIQKGEGGEYMCHAVNIIGEAKSFANVDI-MPQEERVVALPPPV---THQHVMEFDLE 5297

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
             +  +  P   ++  + +++E  +  F+ +V     PE T                    
Sbjct: 5298 HTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFT-------------------- 5337

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETA-FQCRLNVIEKEQVVAPKFVERFSTLNVR 503
              +H  MI ++ +     V     ++ GE    +  L V E    + P+F+       + 
Sbjct: 5338 -PDHKSMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFE----MPPRFIMPICDFKIP 5392

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQ 562
            E    V     +G PTP + W K+ + I P N +  I  + G+ TL I     SD+A Y+
Sbjct: 5393 ENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYR 5452

Query: 563  CTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERAR 622
            C A N  G    R  L            K+  +   + +            +        
Sbjct: 5453 CRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFF------- 5505

Query: 623  PYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEAS 682
                  E   V  PP+FI  +    A  G   +F+  +   G P   + W K+G+ ++  
Sbjct: 5506 ------EFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVR--GSPRPTVYWYKDGKLVQGR 5557

Query: 683  SRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
                     G+ +L + SL   D GEY C A + +G+AE+ A L +T
Sbjct: 5558 RFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 103/397 (25%), Positives = 165/397 (41%), Gaps = 66/397 (16%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P     ++ + V   + A F A  +  G P+ ++ W +    +    +   +HD    
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCA--VISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L +    PED+  YTC A N+ G A TS        ASL +E     +           
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGVATTS--------ASLSVEVPEVVS----------- 3335

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
                  D E+ V   P  IT L   T  SEGQ A ++CR+      +++V WY   K ++
Sbjct: 3336 -----PDQEMPV-YPPAIITPLQD-TVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIK 3385

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS-Q 1947
                +R +       L+I   Y ED G YT  A N +GQ  S+  L++++ ESI+ +  +
Sbjct: 3386 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIE 3445

Query: 1948 HESALE-KIQYLEDDSRYKRAVQDDSFVVEK----------------------PQFGKPI 1984
             E  +E K  + E +S +      D+F   +                      P++ KP 
Sbjct: 3446 QEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPS 3505

Query: 1985 KNAEVT-----EGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFGY--V 2035
               ++T     EG PV     L  +  PT  + W+ N RP+  G R   K   D  +   
Sbjct: 3506 FTQKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            +L+I      D+G+Y   A N+ G A +T+S+ V  K
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 79/297 (26%), Positives = 132/297 (44%), Gaps = 23/297 (7%)

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITV-MQAPQFSRALHNIETVEGTNVHLECR 1333
            I   T  E+  E +   E     T +V   + + +  P     L N+  +EG +V LEC 
Sbjct: 906  ITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECH 965

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            +   G  +  V W+     I++   F+  ++     L +   + EDSG +TC A N+ G 
Sbjct: 966  IS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023

Query: 1394 AVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII--DESVT---------I 1442
              TSC L V   ++   E +  +  EK    E+    +  D++  D S+T          
Sbjct: 1024 VSTSCYLAVQVSEE--FEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLTEEQAGPGEPA 1080

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD--FG 1500
             P F+T+P  ++ ++EG  V F C++    +    V W K+G P+T G+R++  ++   G
Sbjct: 1081 APYFITKP-VVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1137

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
               L I    A+D+G YT    N  G    S  L   +  +++  +Q E  L Q QV
Sbjct: 1138 ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEM-LYQTQV 1193



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 77/263 (29%), Positives = 112/263 (42%), Gaps = 19/263 (7%)

Query: 1699 RHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            R  A  E+    P     +K++ V E ++   E  +   G P   V W R    IE+S  
Sbjct: 931  RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSID 988

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
                   G   L ++    EDSG +TC A+NE G   TS  L VQ   S + E +  +  
Sbjct: 989  FQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--VSEEFEKETTAVT 1046

Query: 1819 QKIQQLED---SSRYQRREDVEVAVNQ-------APRFITQLNGPTKLSEGQSAHYECRI 1868
            +K    E     SR     D  +   Q       AP FIT+     KL EG S  + C++
Sbjct: 1047 EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQV 1105

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTS--NDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
               P P+  V W  +G  L +G+RY+ S     G   L I   + +D+GEYT    N  G
Sbjct: 1106 GGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1163

Query: 1927 QAVSSIRLNVQSKESIIRDSQHE 1949
            +  +S  L  ++   ++  SQ E
Sbjct: 1164 ETSASASLLEEADYELLMKSQQE 1186



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 116/517 (22%), Positives = 208/517 (40%), Gaps = 48/517 (9%)

Query: 4307 DKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQK 4366
            D+    T  K + +         E+V E+  + +   K R  +     +   E+   K+ 
Sbjct: 1965 DRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKD 2024

Query: 4367 QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPV-KPSK---------PPIFTKK 4416
            ++ +E++   +      + E TE E KA  +E  +  P  KP K         P IF ++
Sbjct: 2025 ESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIF-ER 2083

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSILIIRQVFV 4475
            +Q   V +   A F V   G+P P  +WY+    I+ S   +          L+IR V  
Sbjct: 2084 IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTA 2143

Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            EDSA     A N  G     A L+V+ K+      ++  +FT   Q+V       +    
Sbjct: 2144 EDSASIMVKAINIAGETSSHAFLLVQAKQ------LI--TFTQELQDVVAKEKDTMATFE 2195

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T    + V W K+G +V    + ++  +   + L IL     D+  Y CV +      
Sbjct: 2196 CETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NV 2254

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
            +  A+ +V                 A  E ++ L+D  V E  + E  C IV       +
Sbjct: 2255 KTTAKLIVE---------------GAVVEFVKELQDIEVPESYSGELEC-IVSPENIEGK 2298

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            WY  D  +K +  + ++       L + +   ED+G+Y  V      + T   K+K  +P
Sbjct: 2299 WYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMK-PRP 2355

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                 +  L  L D  V EG   Q + +++ +    + W+++G  +  +    ++ +  +
Sbjct: 2356 -----IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQS 2409

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +LLI +  +ED G ++   T  A  + TS ++ V S
Sbjct: 2410 HMLLIEDMTKEDAGNYS--FTIPALGLSTSGRVSVYS 2444



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 65/228 (28%), Positives = 95/228 (41%), Gaps = 27/228 (11%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD-IRNKILEEDGTYT 4570
            +PP F +   +  +           V G    +V W K    ++PD I+  I EE G++T
Sbjct: 5378 MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHT 5437

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARC-------DAECVVSLPATKDKPKPQT------- 4616
            L I      DS  Y C A+N  GEA C       D+E + ++ A K K    +       
Sbjct: 5438 LKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSE-IFAVIAKKSKVTLSSLMEELVL 5496

Query: 4617 -----------KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                       +    PP  I+ + D     G A  F C + G P PTV WYK  KL++ 
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQG 5556

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             ++         + L I+     DEG+Y+CVA N +G     A L +T
Sbjct: 5557 RRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 73/261 (27%), Positives = 114/261 (43%), Gaps = 14/261 (5%)

Query: 3803 MSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            + G + K  E  R+  AP E P+  TPP  ++ +K+ TV E E V  EC +     P   
Sbjct: 919  LHGREAKVTETARVP-APVEIPV--TPPTLVSGLKNVTVIEGESVTLECHISGYPSPT-- 973

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            + WYR    + S   ++  +  G   L I   +AEDSG + C AVN+ G   T   ++ +
Sbjct: 974  VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033

Query: 3923 KLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQ 3982
               +   +         +E    +E+     T +  LTE+      +   P F+T+   Q
Sbjct: 1034 VSEEFEKETTAVTEKFTTEEKRFVESRDVVMT-DTSLTEEQA-GPGEPAAPYFITKPVVQ 1091

Query: 3983 TSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD--FGYVAMNFGWVYP 4040
              LVE  +  F CQ+   G+P   V W  +G PL    R+   Y+   G   +     + 
Sbjct: 1092 -KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFA 1148

Query: 4041 EDSGEYLCRATNLYGMDETKA 4061
            +D+GEY     N +G  ET A
Sbjct: 1149 DDAGEYTIVVRNKHG--ETSA 1167



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 22/283 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            VE+ V   P  ++ L   T + EG+S   EC I  YP P   V WY     ++S   ++ 
Sbjct: 936  VEIPVTP-PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQI 991

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            +   G A L I   + EDSG +TC A+N  G   +S  L VQ  E    + +  +  EK 
Sbjct: 992  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF--EKETTAVTEK- 1048

Query: 1956 QYLEDDSRYKRA----VQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPV------N 2005
             +  ++ R+  +    + D S   E+   G+P     +T+     L    + V       
Sbjct: 1049 -FTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1107

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYD--FGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            +P   V W  +G P+  G+R+K +Y+   G   L I   +A+D G Y     N  GE   
Sbjct: 1108 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSA 1167

Query: 2064 TSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPG 2106
            ++S+  +A   L + +  ++ L + Q     + PK + E  PG
Sbjct: 1168 SASLLEEADYELLMKS-QQEMLYQTQVTAFVQEPK-VGETAPG 1208



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 130/525 (24%), Positives = 210/525 (40%), Gaps = 76/525 (14%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            GR     ++ K+ V + E Q A  E  +    +  +   W+ +G  I    + R  Y   
Sbjct: 3144 GRDVRIRSIKKE-VQVIEKQRAVVEFEV---NEDDVDAHWYKDGIEINFQVQERHKYVVE 3199

Query: 3105 MVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
              +  + I  T+ +D+G Y+  A    G+   SV L     +  + P+    +Q +  ++
Sbjct: 3200 RRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV---NAPEPPQVLQELQPVT-VQ 3251

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G+ A F C V+    P  KI WY   Q +    + K + D     L +      D+  Y
Sbjct: 3252 SGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVY 3309

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282
             C A N YG   T A+++                     E+  +    Q+ P      PP
Sbjct: 3310 TCEAKNDYGVATTSASLSV--------------------EVPEVVSPDQEMP----VYPP 3345

Query: 3283 KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
              IT +QD T   EGQ A F+ R   V   DLKV W+   KK+     +R         L
Sbjct: 3346 AIITPLQD-TVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQL 3401

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLED 3402
            +I   Y E+ G Y  VA+N +G+ S+ ANL   + E+ IL  ++ + +E  +++L +  +
Sbjct: 3402 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES-ILHERIEQEIEMEMKELFSEGE 3460

Query: 3403 SMVRRKDT--------SVEEEKGKAPVFTVPLSNIEN-----------------LREGEN 3437
            S    +DT         ++ +   A  +   +S+  +                 + EGE 
Sbjct: 3461 SEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEP 3520

Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGSR--FRTFCDFGF--VILEISPTYPEDSGEY 3493
              F  RL     P  ++ W+ N + +  G R   +   D       LEI      DSG Y
Sbjct: 3521 VVFTCRLIACPTP--EMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSY 3578

Query: 3494 LCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
               A N+ G A +TAS+ V  K       +  K  E T + + AL
Sbjct: 3579 RLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAERTHENVEAL 3623



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 89/379 (23%), Positives = 159/379 (41%), Gaps = 28/379 (7%)

Query: 4360 VHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQP 4419
            V V+++ + +   V +K  T +    E+ ++     +      GP +P+ P   TK +  
Sbjct: 1032 VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQ 1091

Query: 4420 CRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSILIIRQVFVED 4477
             ++ E     F  +  G P P + W +   P+     +++  +  + +  L+I   F +D
Sbjct: 1092 -KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADD 1150

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            +  +  V  N+ G    SA+L+ E         ++  S         VT+   V+ + KV
Sbjct: 1151 AGEYTIVVRNKHGETSASASLLEEADYE-----LLMKSQQEMLYQTQVTA--FVQ-EPKV 1202

Query: 4538 TGTKPIDVY--WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T P  VY  + K  +K Q  IR K+ ++      +++  Y +D  ++   +       
Sbjct: 1203 GETAPGFVYSEYEKEYEKEQALIRKKMAKDT-----VVVRTYVEDQ-EFHISSFEERLIK 1256

Query: 4596 RCDAECV-VSLPATKDKPKPQTKAAN-APPEIIEP-----LKDKIVAEGQAIEFSCKIVG 4648
              +   +  +L    ++   +  A + +  E +E      +K+  + EG  + F CK+ G
Sbjct: 1257 EIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSG 1316

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             PLP + WYK  K IK  + +QM    D   +LRI    PEDEG Y   A N  G    +
Sbjct: 1317 YPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICS 1376

Query: 4708 AKLKVTQPDQADNLPALTP 4726
             KL V +P      P   P
Sbjct: 1377 GKLYV-EPAAPLGAPTYIP 1394



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 67/227 (29%), Positives = 98/227 (43%), Gaps = 7/227 (3%)

Query: 4315 AKSMAQRYEDNLDQ-TEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVV 4373
            A S AQ+   ++   T + +E RV+ + T  P+ P       +  E  V  +K+    + 
Sbjct: 848  ATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSIT 907

Query: 4374 GDKEITRKITSTETTEIEHKAQTQERVVEGPVK-PSKPPIFTKKMQPCRVFEHEQARFEV 4432
            G    T +    E         T+   V  PV+ P  PP     ++   V E E    E 
Sbjct: 908  GT---TVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
               G P P + WYRE++ I++S DFQI   S  + L+IR+ F EDS  F   A N  GT 
Sbjct: 965  HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 1024

Query: 4493 KCSANLVVE-EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
              S  L V+  +  +     V   FT T +   V S  +V  DT +T
Sbjct: 1025 STSCYLAVQVSEEFEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLT 1070



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 71/236 (30%), Positives = 106/236 (44%), Gaps = 17/236 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP  +  LK+VT +EG  +  E  I   G P+  + W +    IE+S  F   F+ G   
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIAR 999

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIER-TSQHPE--TLQYIQQLED 752
            L +     +DSG +TC AV+  G   T   L V      E+ T+   E  T +  + +E 
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059

Query: 753  YSKYQHQESIEEQTS-----QRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
                    S+ E+ +       P FI +P+  + +L EG +  F  Q+    +P   V W
Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVEGGSVVFGCQVG--GNPKPHVYW 1115

Query: 807  YKDGRPITASSRITSIFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
             K G P+T   R    +N   G   L I    A+DAG YT+   NK GE  ++AS+
Sbjct: 1116 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 52/206 (25%), Positives = 97/206 (47%), Gaps = 4/206 (1%)

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSK 4667
            ++  + Q +    P  +++P+  K + EGQ   F  K+VG+P+P   W+  G +++    
Sbjct: 1444 EETDESQLERLYKPVFVLKPVSFKCL-EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYT 1502

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +  + +     +L I  A P D G++  VA N AGR +++  L V   +       +  L
Sbjct: 1503 HKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKL 1562

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI--PETPDFQMIHEGNNAVLLIGNTYE 4785
            +++ + EG   + K + T    P I WL+   +I   + P  ++      A L I +T  
Sbjct: 1563 KNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVS 1622

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            +D+  +T  A   AG+  T  K+ V+
Sbjct: 1623 QDSAWYTATAINKAGRDTTRCKVNVE 1648



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 99/387 (25%), Positives = 153/387 (39%), Gaps = 67/387 (17%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++ G  A F A +   G    ++ W K+ + +    +     +     L +      D
Sbjct: 3248 VTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 3305

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK 1038
            A  YTC A N  G ATTSA+L++   + +  + + P                        
Sbjct: 3306 AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP------------------------ 3341

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
                P  + PL+ T    EGQ A F+ RV   S   + V WY   K+I  +   +     
Sbjct: 3342 -VYPPAIITPLQDT-VTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFE 3396

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI----------------- 1141
                L+IA    ED G YT VA NA G+   +A++++E   SI                 
Sbjct: 3397 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELF 3456

Query: 1142 -DTSSIH-----RGLYEKTRHIEESKFVEPMYQIEEISKS------KPVFVQPLSNPPPV 1189
             +  S H     R  +  +  I+        Y     S S      KP F Q L+    V
Sbjct: 3457 SEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTF-KYV 3515

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR--FKTYYDFGF--VALDIIHATSA 1245
             EG+ +   CRL  +  PT  + WFHN R +  G R   K   D      +L+I      
Sbjct: 3516 LEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDR 3573

Query: 1246 DTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            D+G Y + A+N  GSA ++A + VI++
Sbjct: 3574 DSGSYRLLAINSEGSAESTASLLVIQK 3600



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 87/347 (25%), Positives = 143/347 (41%), Gaps = 29/347 (8%)

Query: 242  KRYVGESDVQIS-TEI-DRSLGPVSP--PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
            KR+V   DV ++ T + +   GP  P  P    KP   KL EG    F  Q+ GNP+P V
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113

Query: 298  TWFKNGQRLINSNKHEIITTHNHTT----LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
             W K+G  L    ++++  ++N  T    L +  T   D+G YT++  N +G    S  L
Sbjct: 1114 YWKKSGVPLTTGYRYKV--SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171

Query: 354  AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
              E+  E  ++ Q+ + +  TQ     +  ++ E   AP FV    +++    K      
Sbjct: 1172 LEEADYELLMKSQQ-EMLYQTQVTAFVQEPKVGE--TAPGFVYSEYEKEYE--KEQALIR 1226

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
            +   +    V  ++ D++       + L+ E       I   TL +          + GE
Sbjct: 1227 KKMAKDTVVVRTYVEDQEFHISSFEERLIKEI---EYRIIKTTLEE-------LLEEDGE 1276

Query: 474  TAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
               +  +++ E E  V   F  R     + EG  V  + +  G P P+I W KDG  I  
Sbjct: 1277 E--KMAVDISESE-AVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKH 1333

Query: 534  NPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
                ++     G ++L IP     D   Y   A N+ G+     +LY
Sbjct: 1334 GERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLY 1380



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 62/263 (23%), Positives = 119/263 (45%), Gaps = 33/263 (12%)

Query: 1831 QRREDVEVAVN--QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
            + R  V + VN  + P+ + +L  P  +  G+ A +   I   P P  ++ WY   ++L 
Sbjct: 3224 RNRSSVTLYVNAPEPPQVLQELQ-PVTVQSGKPARFCAVISGRPQP--KISWYKEEQLLS 3280

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
            +G + +  +D     L ++  + ED+  YTC+A N+ G A +S  L+V+  E +      
Sbjct: 3281 TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVS----- 3335

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008
                                 D    V  P    P+++   +EG P   +     V+   
Sbjct: 3336 --------------------PDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTD 3372

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            ++V WY   + ++    F+ T       L+I  AY ED GTY   A+NAVG+  +T+++ 
Sbjct: 3373 LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 3432

Query: 2069 VDAKSGLYLDTLDEQRLKKIQEL 2091
            ++A   +  + ++++   +++EL
Sbjct: 3433 LEAPESILHERIEQEIEMEMKEL 3455



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 76/271 (28%), Positives = 117/271 (43%), Gaps = 38/271 (14%)

Query: 3546 DTLTPEAESG-NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            + ++P+ E    PP   T   D + SE   A F+CR   V+ + ++V W+   K +   S
Sbjct: 3332 EVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP-S 3387

Query: 3605 RVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGII------- 3656
            R   +  F     LEI   Y  D G YT  A+N  G+ + +  L ++  + I+       
Sbjct: 3388 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447

Query: 3657 LEPQLPSHFKSG---------TESIQKLEETLHK-------REEITIEDEKPN--PPRFT 3698
            +E ++   F  G          ++    E+  HK          I+     P    P FT
Sbjct: 3448 IEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFT 3507

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGF--IA 3754
             ++     V EG PV F CR+  +  PT  + WFHN RP  TG R  +   +D      +
Sbjct: 3508 QKLTFKY-VLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSS 3564

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L+I  +  RD+G Y   A N  GSA +TA +
Sbjct: 3565 LEIKRVQDRDSGSYRLLAINSEGSAESTASL 3595



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 62/240 (25%), Positives = 105/240 (43%), Gaps = 23/240 (9%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP++ Q+ +   +Q G  A+F   +SG P+P+++W+K  Q L    K + +      TL 
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +      D+  YT  A+N  G   TS  L+VE P E    DQ                  
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP-EVVSPDQEM---------------- 3340

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P  +   QD   +EG+  RF CRV+G    +V+W+  D++I+     ++   E
Sbjct: 3341 ---PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFE 3396

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
               + L I      D G  T VA N  G+ +    L++   E ++  + +E+   + ++E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHER-IEQEIEMEMKE 3454



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 101/454 (22%), Positives = 172/454 (37%), Gaps = 58/454 (12%)

Query: 4396 TQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP 4455
            T    +E P     PP F + +   +V+E+    F VE +G P+P +KWYR    ++  P
Sbjct: 5169 TPNEAIE-PKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLE--P 5225

Query: 4456 DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
            D +I      ++          S   + + +  GG   C A  ++ E +      I+P  
Sbjct: 5226 DERIKMERVGNVC---------SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQE 5276

Query: 4516 FTLTAQNVNVTSGQLVRLDTKVTGTK--PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
              + A    VT   ++  D + T +   P     +   +  + D++    E +    ++ 
Sbjct: 5277 ERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLEVELSEKDVK----EFEKQVKIVT 5332

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
            +  +  D  K   V+++       D   + S      + K   +    PP  I P+ D  
Sbjct: 5333 VPEFTPDH-KSMIVSLDVLPFNFVDPN-MDSREGEDKELKIDLEVFEMPPRFIMPICDFK 5390

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY-FQMSRTADEYTLRISEAFPEDEGD 4692
            + E     F C ++G P P V+WYK    I+P    + +S     +TL+I      D   
Sbjct: 5391 IPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSAT 5450

Query: 4693 YKCVAYNSAGR---------------VTVAAKLKVTQPDQADNLPALTPLRD----IVVY 4733
            Y+C A N  G                  +A K KVT     + L   +   D      V 
Sbjct: 5451 YRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVV 5510

Query: 4734 EGQP----------------AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN-A 4776
            EG P                A F+  +    +PT+ W ++G L+ +   F +   G    
Sbjct: 5511 EGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRRFTVEESGTGFH 5569

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L I +  + D G + C AT  +G  E+ A L +
Sbjct: 5570 NLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 78/308 (25%), Positives = 130/308 (42%), Gaps = 41/308 (13%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
            GR  +         ++VNV  G    L+ KV+      V W  N ++++PD R + + + 
Sbjct: 2438 GRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2497

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
                L+I   +  D G Y+ +        R +  C +S+   K               II
Sbjct: 2498 TKQRLVINRTHASDEGPYKLIV------GRVETNCNLSVEKIK---------------II 2536

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              L+D    E Q + F  ++    +  V W   DK IKPS  +++      Y L +    
Sbjct: 2537 RGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMM 2595

Query: 4687 PEDEGDYKCVAYNS--AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
             +DEG Y   A  +  +G++TVA                  PL D  V E Q A F+ ++
Sbjct: 2596 KDDEGKYTFYAGENITSGKLTVAGGA------------ISKPLTDQTVAESQEAVFECEV 2643

Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
             +      +WLR+G  +P T + +   +G+   L+I  T  +D G +T +  T+    +T
Sbjct: 2644 ANPDSKG-EWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KT 2698

Query: 4805 SAKLVVKS 4812
            SAKL V++
Sbjct: 2699 SAKLKVEA 2706



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 98/399 (24%), Positives = 165/399 (41%), Gaps = 52/399 (13%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            KK +     E+    FEV    + +P +KW+ +N  IK S   ++ +      L+++ + 
Sbjct: 2799 KKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 2857

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
              D+  + AV     G  +C A L VE               T T +N+ V   +    +
Sbjct: 2858 PSDAGEYTAVV----GQLECKAKLFVETLH-----------ITKTMKNIEVPETKTASFE 2902

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +V+    +   WLKNG +++   + KI+ +   + L+I+    +DS +Y  V     G 
Sbjct: 2903 CEVSHFN-VPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGN 2957

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V+                 P  I   LKD    E   I F   +  + + + 
Sbjct: 2958 DQVSATLTVT-----------------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SY 2999

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W K    IK +   QM      ++L I      D  DY  V    AG+ T  A L V  
Sbjct: 3000 KWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFV----AGKATSTATLYV-- 3053

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
              +A ++     ++DI V E + A F+ ++ S+   T+QW+++   +  T   ++  E  
Sbjct: 3054 --EARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               LLI +T   D G +T     A G V T AKL V+ +
Sbjct: 3111 VHRLLIPSTRMSDAGKYT---VVAGGNVST-AKLFVEGR 3145



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 96/398 (24%), Positives = 164/398 (41%), Gaps = 68/398 (17%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + P     L+ V ++ G+ A F    +       K+ WY   + L +G +    ++    
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARF--CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTS 1695
             L ++   PED+  YTC A N  G A TS    V   + +                    
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVV-------------------- 3334

Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
                 S   E+    P    P++D   +E Q A F+ R   V    L+V W      I+ 
Sbjct: 3335 -----SPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 3386

Query: 1756 SN--RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL---QL 1810
            S   R+T   D   + +   Y  PED GTYT  A N +G+  +++ L +++  S+   ++
Sbjct: 3387 SRFFRMTQFEDTYQLEIAEAY--PEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3444

Query: 1811 ESQHESALQKI---QQLEDSSR-----YQRREDVEVAVNQAPRFITQLNGPT-------- 1854
            E + E  ++++    + E S R     +   ED++     A R+ ++++  +        
Sbjct: 3445 EQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKP 3504

Query: 1855 ----KLS-----EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR--YRTSNDFGF-- 1901
                KL+     EG+   + CR+   P P M   W+ N + + +G R   +  +D     
Sbjct: 3505 SFTQKLTFKYVLEGEPVVFTCRLIACPTPEM--TWFHNNRPIPTGLRRIIKAESDLHHHS 3562

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            ++L+I  V   DSG Y   AIN+ G A S+  L V  K
Sbjct: 3563 SSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 72/298 (24%), Positives = 117/298 (39%), Gaps = 16/298 (5%)

Query: 3513 QGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI---- 3568
            + +  + ++ ++   + GT  +    E   G    +T  A    P E   TP  L+    
Sbjct: 891  KSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLK 950

Query: 3569 ---LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
               + E  S   EC +      S  V W+     + +    +     G   L I   +  
Sbjct: 951  NVTVIEGESVTLECHISGY--PSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 1008

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ-LPSHFKSGTESIQKLEETLHKREE 3684
            D+G +TC A N  G  + SC L V+  +    E   +   F +  +   +  + +     
Sbjct: 1009 DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTS 1068

Query: 3685 ITIEDEKPNPPRFTVEIKDNI--DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742
            +T E   P  P     I   +   + EGG V F C+V   G+P   + W  +G P  TG 
Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1126

Query: 3743 R--VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
            R  V      G   L I   +A DAGEYT    NK G  + +A +   A  +++++SQ
Sbjct: 1127 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/282 (24%), Positives = 121/282 (42%), Gaps = 20/282 (7%)

Query: 3667 SGTESIQKLEETLHKREEITIED-------EKPNPPRFTVEIKDNIDVPEGGPVHFDCRV 3719
            +GT   ++  E LH RE    E        E P  P   V    N+ V EG  V  +C +
Sbjct: 907  TGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHI 966

Query: 3720 EPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779
               G P+  + W+       +          G   L I   +A D+G +TC A N+ G+ 
Sbjct: 967  S--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 1024

Query: 3780 TTTAKITCSAKRDIVLESQ-LPQGMSGEKIKELERGRI--SDAPKEE----PIVSTPPKF 3832
            +T+  +      +   E+  + +  + E+ + +E   +  +D    E    P     P F
Sbjct: 1025 STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1084

Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM--GFVSLD 3890
            IT+     + E   V F C+V    +PK  + W ++G  L +G+RY+  Y+   G   L 
Sbjct: 1085 ITKPVVQKLVEGGSVVFGCQVGG--NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLV 1142

Query: 3891 ILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            I   +A+D+GEY     N  GE    A++  +   ++++++Q
Sbjct: 1143 ISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/271 (25%), Positives = 121/271 (44%), Gaps = 16/271 (5%)

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320
            RE +  + A+   P      PP  ++ +++VT ++EG+S   E  +     P   V W+ 
Sbjct: 922  REAKVTETARVPAPVEIPVTPPTLVSGLKNVT-VIEGESVTLECHISGYPSPT--VTWYR 978

Query: 3321 NGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
               ++     ++     GI  L I   + E+SG + C A N+ G  ST   L     E  
Sbjct: 979  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 1038

Query: 3381 ILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKG-----KAPVF-TVPLSNIENLRE 3434
              ++      +   E+ + +E   V   DTS+ EE+       AP F T P+  ++ L E
Sbjct: 1039 EKETTAVT-EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVE 1095

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSGE 3492
            G +  F  ++     P+  V W  +G  L  G R++   +   G   L IS T+ +D+GE
Sbjct: 1096 GGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1153

Query: 3493 YLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            Y     N +GE   +AS+  +    ++++SQ
Sbjct: 1154 YTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 16/234 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLS--GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            P   +K  + +L+    A F+ +L+  G+P   V W  +G+ L  +N+  +I    + +L
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1762

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG  T  A N  G   TS  L V+       + Q  +     Q+ E  ER+
Sbjct: 1763 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1822

Query: 384  EISEKALA-----------PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
               E AL            P  V   +   V EG+  RF CRVTG P P+V W++N + I
Sbjct: 1823 -AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLI 1881

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
            R   + +  V   G H L I +    D+G V   A N  G    + +L + ++E
Sbjct: 1882 RK--SKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1933



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 82/271 (30%), Positives = 115/271 (42%), Gaps = 39/271 (14%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P    PL +     EG+ A F+ R++ TD   LKV WY   K +K    FR         
Sbjct: 3345 PAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFRMTQFEDTYQ 3400

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNII---LESQLPKGM-----EGT 3531
            LEI+  YPED G Y   A N  G+  +TA++ ++   +I+   +E ++   M     EG 
Sbjct: 3401 LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGE 3460

Query: 3532 -----------------ID-KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENS 3573
                             ID K  A + Y+  + + +   E   P  FT   +   + E  
Sbjct: 3461 SEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKP-SFTQKLTFKYVLEGE 3519

Query: 3574 SAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR--VKTINDFGF--VILEIGGVYQRDAGL 3629
               F CRLI      M   WFHN +P+ TG R  +K  +D       LEI  V  RD+G 
Sbjct: 3520 PVVFTCRLIACPTPEMT--WFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGS 3577

Query: 3630 YTCKATNRHG--EATVSCKLQVKGRQGIILE 3658
            Y   A N  G  E+T S  +  KG+    LE
Sbjct: 3578 YRLLAINSEGSAESTASLLVIQKGQDEKYLE 3608



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 32/287 (11%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            K+ W+K  Q ++ G + + +HD     L +I+   ED+ +YTC A N  G    S  L+ 
Sbjct: 3269 KISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3328

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
                ++V   Q                        E+    P   T L++    EGQ A 
Sbjct: 3329 E-VPEVVSPDQ------------------------EMPVYPPAIITPLQDTVTSEGQPAR 3363

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656
            F+ R   VS   LKV WY  +K +K    F  T       L+I    PED GTYT  A N
Sbjct: 3364 FQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASN 3420

Query: 1657 ALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL--EDTSKYQRHSAQDEVITQAPVFT 1714
            A+G+  ++    + + +SI  E   +     + +L  E  S++     +D       +  
Sbjct: 3421 AVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDH 3480

Query: 1715 MPMKDIRVAE--NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
              M   R A   +  + +     P    KL  +++  G P+  + RL
Sbjct: 3481 KSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRL 3527



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 76/284 (26%), Positives = 117/284 (41%), Gaps = 24/284 (8%)

Query: 1553 EQIQVLEDR-SKYHRTDMVD---EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDAT 1608
            E+ +VL  R +K   T  V    E+    P   + LKNV + EG+    E  +      T
Sbjct: 914  ERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT 973

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
              V WY  +  ++S   F  T   G   L I     EDSG +TC A+N  G   TS    
Sbjct: 974  --VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLA 1031

Query: 1669 VHSKKSIYLES----------QHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVF-TMPM 1717
            V   +    E+          +      R   + DTS  +  +   E    AP F T P+
Sbjct: 1032 VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGE--PAAPYFITKPV 1089

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYVALNMKYV 1775
               ++ E  +  F  ++   G+PK  V W ++GVP+    R    ++   G   L +   
Sbjct: 1090 VQ-KLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMT 1146

Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
              +D+G YT    N+ GE   S++L  ++   L ++SQ E   Q
Sbjct: 1147 FADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQ 1190



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 3/183 (1%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            ++IE+S    AP+  +  Q + V +G    F  RV G+P PE  W+ N  +I        
Sbjct: 2067 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2126

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
               E     L+I +VT  DS  +   A N +GET+    L +++ +Q++   F +    +
Sbjct: 2127 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLIT--FTQELQDV 2183

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +E + +         P  ++ W KDG+ +    + R+H+D     L I     SDA  
Sbjct: 2184 VAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAED 2243

Query: 561  YQC 563
            Y C
Sbjct: 2244 YSC 2246



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 69/247 (27%), Positives = 97/247 (39%), Gaps = 11/247 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P     L N+  + EGE+   E  ++    P   V WY     +++   F+     G   
Sbjct: 943  PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIAR 999

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDK-IAAL 3538
            L I   + EDSG + C A N  G   T+  + VQ       E+        T +K     
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059

Query: 3539 EGYSGTVDTLTPE-AESGNP--PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
                 T  +LT E A  G P  P F T P    L E  S  F C++    +    V W  
Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKK 1117

Query: 3596 NGKPLLTGSRVKTI--NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G PL TG R K       G   L I   +  DAG YT    N+HGE + S  L  +   
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1177

Query: 3654 GIILEPQ 3660
             ++++ Q
Sbjct: 1178 ELLMKSQ 1184



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 37/91 (40%), Positives = 51/91 (56%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP ++  LK+  V EG+++   C I G P PTV WY+ D  I+ S  FQ++  +    L 
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            I EAF ED G + C A N AG V+ +  L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 65/233 (27%), Positives = 94/233 (40%), Gaps = 15/233 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
            EG+    E  +   G PS    WY    +++    F+ T   G   L I    A D+G +
Sbjct: 956  EGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013

Query: 2582 MCKAINRAGXXXXX------XXXXXXXXXXIIDQAMRPESWEQIQLKEAAM--NKVPEMF 2633
             C A+N AG                      + +    E    ++ ++  M    + E  
Sbjct: 1014 TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1073

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
               G   AP F T      KLVEG  V    QV     P+  + W K+GV LTTG R K 
Sbjct: 1074 AGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKV 1130

Query: 2694 TFD--FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
            +++   G   L I+    DD+G YT    N  GE  ++AS+  E  + LL +S
Sbjct: 1131 SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1183



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 75/321 (23%), Positives = 126/321 (39%), Gaps = 27/321 (8%)

Query: 240  ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
            + +   G S + +   ++     V P    +K +N  ++EG+  + +V+ +GNP P + W
Sbjct: 1531 VAQNRAGRSSISVILTVEAVEHQVKP-MFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVW 1589

Query: 300  FKNGQRLINSN--KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE- 356
             KN   ++     K  I  T     L++ +T   DS  YT  A N  G   T   + VE 
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649

Query: 357  ------------SPTESY------VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
                         P  +Y        +    ++   Q++  E  +   EK   P F K  
Sbjct: 1650 EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKL 1709

Query: 399  QDRDVTEGKMTRFDCRVT--GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
                +       F+CR+T  G P   V W ++D +  +  N   ++NE G  +L      
Sbjct: 1710 TSLRLKRFGPAHFECRLTPIGDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLDYGVAY 1768

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE--RFSTLNVREGEPVVLNARA 514
              DSG++TC A NK G       L V +++ +V    +   R     + E E +      
Sbjct: 1769 SRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGAL 1828

Query: 515  VGTPTPRITWQKDGVPIIPNP 535
             G  T +   QK  + + P P
Sbjct: 1829 TGVTTDQKEKQKPDIVLYPEP 1849



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 86/373 (23%), Positives = 137/373 (36%), Gaps = 34/373 (9%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            PQ ++  Q   V  GK  RF   ++GRP P+++W+  ++ +   +  K L ++   + L+
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL-HDGQEYTLL 3297

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNV-----IEKEQ---VVAPKFVERFSTLNVR 503
            +      D+ V TC A+N  G       L+V     +  +Q   V  P  +         
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3357

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            EG+P     R  GT   +++W      I P+   R+        L+I  A   D   Y  
Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3416

Query: 564  TAQNVAG---STAT------RARLYXXXXXXXXXXQKRL-------HLPRPTKVXXXXXX 607
             A N  G   STA        + L+           K L       H  R T+       
Sbjct: 3417 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSE 3476

Query: 608  XXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPT 667
                       +R    I        Y  P F   L     +EG  + F  R+  +  PT
Sbjct: 3477 DIDHKSMA--AKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRL--IACPT 3532

Query: 668  MKIEWLKNGQSIEASSR----FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
             ++ W  N + I    R      S       SL++  +  +DSG Y   A+++ G AE+ 
Sbjct: 3533 PEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAEST 3592

Query: 724  AVLHVTPRATIER 736
            A L V  +   E+
Sbjct: 3593 ASLLVIQKGQDEK 3605



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 83/363 (22%), Positives = 147/363 (40%), Gaps = 56/363 (15%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI W+K    L+TG + K   D    TL +     +D+ +YTC+A N  G A ++AS
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            + +E     + E + PD    +                       I+ L + V  EG   
Sbjct: 3326 LSVE-----VPEVVSPDQEMPV------------------YPPAIITPLQDTVTSEGQPA 3362

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851
             F+C V  +    LK+ W+  +K +     ++ T       L+I   Y ED G YT  A+
Sbjct: 3363 RFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVAS 3419

Query: 2852 NSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGL-EAVEQAEEARLAKGRRPSVPDTE--- 2907
            N+ G  +++ +L     ++I  +    + +  + E   + E     +  R +  D+E   
Sbjct: 3420 NAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDID 3479

Query: 2908 --------YPK--------PEWIIPIAAE----HQLVEGQVLHLEGQVEPKNDPDLKIEW 2947
                    Y          PE+  P   +      ++EG+ +    ++     P++   W
Sbjct: 3480 HKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEM--TW 3537

Query: 2948 YFNGKVLEQGSR--FKLTSDFGF--VTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYC 3003
            + N + +  G R   K  SD      +L++  V +RDSG Y   A N  G A +++++  
Sbjct: 3538 FHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597

Query: 3004 TSK 3006
              K
Sbjct: 3598 IQK 3600



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 64/250 (25%), Positives = 108/250 (43%), Gaps = 36/250 (14%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W+   Q +  G + +  HD     L ++  + ED+  Y C+A N  G A  + +
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325

Query: 2199 LKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            L V     +  D + P                        + PP  +T L+ T    EG+
Sbjct: 3326 LSVEVPEVVSPDQEMP------------------------VYPPAIITPLQDTV-TSEGQ 3360

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT-FDFGYVSLDIQHCVPEDAGEYSV 2317
             A F+C+V      +L++ +Y   K ++ +  F +T F+  Y  L+I    PED G Y+ 
Sbjct: 3361 PARFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTY-QLEIAEAYPEDEGTYTF 3416

Query: 2318 KAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
             A NA+G  +S  ++++ A  SI+ E      +E+  E+E  E F   E        R  
Sbjct: 3417 VASNAVGQVSSTANLSLEAPESILHER-----IEQEIEMEMKELFSEGESEHSERDTRDA 3471

Query: 2378 FTQPLQNIDN 2387
            F+   ++ID+
Sbjct: 3472 FSDS-EDIDH 3480



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 68/248 (27%), Positives = 105/248 (42%), Gaps = 17/248 (6%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ +T  P  +  LK    ++EG+S   E  +      T+T  WY    QI S+   Q  
Sbjct: 937  EIPVTP-PTLVSGLKNVT-VIEGESVTLECHISGYPSPTVT--WYREDYQIESSIDFQIT 992

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID---TSSIHRGLYE 1152
               G   L I    AEDSG +T  A N AG    S  + V+     +   T+   +   E
Sbjct: 993  FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTE 1052

Query: 1153 KTRHIEESKFV--EPMYQIEEISKSKPVFVQPLSNP--PPVSEGKNIHLECRLEPMGDPT 1208
            + R +E    V  +     E+    +P     ++ P    + EG ++   C++   G+P 
Sbjct: 1053 EKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPK 1110

Query: 1209 MRVEWFHNGRSVTVGSRFKTYYD--FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
              V W  +G  +T G R+K  Y+   G   L I    + D GEYT+   N  G   TSA 
Sbjct: 1111 PHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG--ETSAS 1168

Query: 1267 VRVIERSD 1274
              ++E +D
Sbjct: 1169 ASLLEEAD 1176



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 75/317 (23%), Positives = 135/317 (42%), Gaps = 23/317 (7%)

Query: 2041 YAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPI 2100
            + +A+   TY  +A   V + V  S      +   + + L   R  K+ E  +   P P+
Sbjct: 881  FPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERF-EVL-HGREAKVTETARV--PAPV 936

Query: 2101 EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT 2160
            E   P   P  ++ L ++  + EG+    EC +     P  T+ W+    +I +   ++ 
Sbjct: 937  EI--PVTPPTLVSGLKNVTVI-EGESVTLECHISGYPSP--TVTWYREDYQIESSIDFQI 991

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT---QHPNGL 2217
            T   G   L I   +AEDSG + C A N+ G    +C L V        +T         
Sbjct: 992  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTT 1051

Query: 2218 EKIRQLEAQG-HSTRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQVEPVHD 2271
            E+ R +E++    T   + E +  P     P F+T+      + EG +  F CQV    +
Sbjct: 1052 EEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GN 1108

Query: 2272 PNLRIEFYHNGKALQSAARFHITFD--FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSA 2329
            P   + +  +G  L +  R+ ++++   G   L I     +DAGEY++   N  G  +++
Sbjct: 1109 PKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1168

Query: 2330 ISMTVTAKGSIISESQR 2346
             S+   A   ++ +SQ+
Sbjct: 1169 ASLLEEADYELLMKSQQ 1185



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 7/195 (3%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  V+ +++ T ++E E+   EC ++  G P+  V W+     +     F   +  G  
Sbjct: 942  PPTLVSGLKNVT-VIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIA 998

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
             +     + EDSG + C A N  G   T   +          ++       + E+ R +E
Sbjct: 999  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1058

Query: 4092 ASWQVTPEQVVEESKAR----CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
            +   V  +  + E +A       P F++ P    + EG    F C+V G+PKP V W  +
Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1118

Query: 4148 GNTIVNGSRYKLTYD 4162
            G  +  G RYK++Y+
Sbjct: 1119 GVPLTTGYRYKVSYN 1133



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 93/390 (23%), Positives = 156/390 (40%), Gaps = 65/390 (16%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P  +Q L  P  V  GK     C +   G P  ++ W+   + ++ G + K  +D     
Sbjct: 3239 PQVLQELQ-PVTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L +I A   D   YT  A N  G A TSA + V E  ++V+  Q                
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEMP------------- 3341

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
                       +  P     L +  T EG     +CR   V    ++V W+   K IK  
Sbjct: 3342 -----------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPS 3387

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI---LESQ 1413
              FR     D   L++   YPED G YT  A+N +G+  ++  L + A + ++   +E +
Sbjct: 3388 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447

Query: 1414 HPSGLEKI------QYLEDTSR--YKKTDIIDESVTIKPRFVTRPKSIEN---------- 1455
                ++++      ++ E  +R  +  ++ ID       R+ +R  S  +          
Sbjct: 3448 IEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFT 3507

Query: 1456 -------VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR--FRPIHDFGY--VAL 1504
                   V+EG+ V F C+L  +     ++ WF N +P+  G R   +   D  +   +L
Sbjct: 3508 QKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSL 3565

Query: 1505 DIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            +I  +   DSG Y   A+N  G+ E +  L
Sbjct: 3566 EIKRVQDRDSGSYRLLAINSEGSAESTASL 3595



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 77/331 (23%), Positives = 137/331 (41%), Gaps = 23/331 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I   P   ++ EG  A+F+ +++G P+P+V W+ NGQ +  S +  +     H  L +
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHY-LDI 1899

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-----SYVQDQRSQYITDTQ---QR 377
             + +  D+G   + AENP G I     L ++   +         + R ++        Q 
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQF 1959

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKM--------TRFDCRVTGRPYPEVTWFIND 429
            E ++     +     + VK+ +   +T  K+        ++F  R T   Y E    +  
Sbjct: 1960 EVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR-TEEGYYEAITAVEL 2018

Query: 430  RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQV 488
            +  + D +++ L+ ++ +  L  T   L++          K     F  + + IE    +
Sbjct: 2019 KSRKKDESYEELLRKTKDELLHWTK-ELTEEEKKALAEEGKITIPTF--KPDKIELSPSM 2075

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH-TDGGAST 547
             APK  ER  +  V +G       R VG P P   W K+GV I  +  +  +  +     
Sbjct: 2076 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135

Query: 548  LDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            L I    A D+A     A N+AG T++ A L
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFL 2166



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 117/499 (23%), Positives = 194/499 (38%), Gaps = 71/499 (14%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PPQ +  L+ VT   G    F   I   G P  KI W K  Q +    +   +      +
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L ++    +D+  YTC A +  GVA T A L V          + PE +   Q++  Y  
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQEMPVYP- 3344

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                          P  I PLQD     EG+ A F+ +   VS   ++V WY   + I  
Sbjct: 3345 --------------PAIITPLQDT-VTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 3386

Query: 816  SS--RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV----- 868
            S   R+T  F   Y  L I     ED G+YT  A N +G+  STA++ + A  ++     
Sbjct: 3387 SRFFRMTQ-FEDTY-QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3444

Query: 869  -------TADLGIPEQRRYIEKTXXXXXX-------XXXXXXXXXXXVPESTQKPE-FKT 913
                     +L    +  + E+                         +  ++  PE FK 
Sbjct: 3445 EQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKP 3504

Query: 914  PIKDQISIK---EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR----ITTFFNFGY 966
                +++ K   EG    F  RL  I   T  + W  + RP+    R      +  +   
Sbjct: 3505 SFTQKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHS 3562

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYL-ED 1025
             +L IK V   D+G Y   A N+ G A ++A+L ++ K     + ++   L++ +   E+
Sbjct: 3563 SSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQ---DEKYLEFLKRAERTHEN 3619

Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQ 1085
                 +R E+ +K+    RF G      + VE +        +  S    T ++ ++ + 
Sbjct: 3620 VEALVERGEDRIKVDL--RFTGSPFNKKQDVEQKGMMRTIHFKTMSSAKKT-DYMYDEEY 3676

Query: 1086 ITSANRIQTYHDFGYVALD 1104
            + S + I+ + + G   LD
Sbjct: 3677 LESKSDIRGWLNVGESFLD 3695



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 70/265 (26%), Positives = 116/265 (43%), Gaps = 42/265 (15%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV PP I    +++   EG  A+FQ ++SG    +V+W+   +++  S    +    +  
Sbjct: 3341 PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3399

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYI---------- 371
             L +      D G YT +A N  G + ++  L++E+P ES + ++  Q I          
Sbjct: 3400 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP-ESILHERIEQEIEMEMKELFSE 3458

Query: 372  --TDTQQRETEERI----EISEKALA--------------PQFVKVCQDRDVT-----EG 406
              ++  +R+T +      +I  K++A              P++ K    + +T     EG
Sbjct: 3459 GESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEG 3518

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH----ALMITNVTLSDSGV 462
            +   F CR+   P PE+TWF N+R I      +I+  ES  H    +L I  V   DSG 
Sbjct: 3519 EPVVFTCRLIACPTPEMTWFHNNRPIPTGL-RRIIKAESDLHHHSSSLEIKRVQDRDSGS 3577

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQ 487
               +A N  G       L VI+K Q
Sbjct: 3578 YRLLAINSEGSAESTASLLVIQKGQ 3602



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 59/243 (24%), Positives = 98/243 (40%), Gaps = 9/243 (3%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +S L N+   EG+++  EC++     PT  + W+  +  + S   ++ T       L I 
Sbjct: 946  VSGLKNVTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIR 1003

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEA---VEQAEEA 2893
              + EDSG +TC A N  G+ +TS  L     +    +T     K   E    VE  +  
Sbjct: 1004 EAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVV 1063

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
                           P   + I      +LVEG  +    QV    +P   + W  +G  
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVP 1121

Query: 2954 LEQGSRFKLT--SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011
            L  G R+K++     G   L +   +  D+G YT    NK GE   S+++   +   L+ 
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1181

Query: 3012 RTQ 3014
            ++Q
Sbjct: 1182 KSQ 1184



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 106/509 (20%), Positives = 190/509 (37%), Gaps = 60/509 (11%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            ++ +W  NG +I S ++ Q        +L+I +V   D+  YT VA  A   A L     
Sbjct: 2997 ISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEAR 3056

Query: 1135 -VETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGK 1193
             +E R  I    +     EK R + E +  EP   ++ +   + +    +++   + + K
Sbjct: 3057 HIEFRKHIKDIKV----LEKKRAMFECEVSEPDITVQWMKDDQEL---QITDRIKIQKEK 3109

Query: 1194 NIHL----ECRLEPMGDPTM-------RVEWFHNGRSVTVGSRFKTYYDFGFVALDI--- 1239
             +H       R+   G  T+         + F  GR V + S  K           +   
Sbjct: 3110 YVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFE 3169

Query: 1240 IHATSADTGEYT--VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARR 1297
            ++    D   Y   +     +   H   + R I R   +++T+   A E   +   A R 
Sbjct: 3170 VNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM-FISETRQSDAGEYTFV---AGRN 3225

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
               V   +   + PQ  + L  +    G      C +   G    ++ W+   + + TG 
Sbjct: 3226 RSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGF 3283

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSG 1417
            + +  ++     L L+  +PED+ VYTC+A N  G A TS +L V   + +  + + P  
Sbjct: 3284 KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP-- 3341

Query: 1418 LEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK 1477
                                    + P  +  P       EGQ   F+C+   V+ ++LK
Sbjct: 3342 ------------------------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLK 3374

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            V W+   + +     FR         L+I +   ED G YT  A N VG    +  L+  
Sbjct: 3375 VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3434

Query: 1538 STTDIVRS-TQNEAGLEQIQVLEDRSKYH 1565
            +   I+    + E  +E  ++  +    H
Sbjct: 3435 APESILHERIEQEIEMEMKELFSEGESEH 3463



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 73/288 (25%), Positives = 118/288 (40%), Gaps = 17/288 (5%)

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            T  + T   K  IV    LP       +   E G   +   +  +   PP+FI  I    
Sbjct: 5332 TVPEFTPDHKSMIVSLDVLPFNFVDPNMDSRE-GEDKELKIDLEVFEMPPRFIMPICDFK 5390

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSGHRYRTVYDMGFVSLDILYVYAEDS 3899
            + E+    F+C V     P+  ++WY+    + P   +Y    + G  +L I  V   DS
Sbjct: 5391 IPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDS 5448

Query: 3900 GEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYL 3959
              Y CRAVN  GE   +  ++   + D  +   + +  K + +    E  +K   ++ + 
Sbjct: 5449 ATYRCRAVNCVGEAICRGFLT---MGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFF 5505

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
                 + V  + PPRF+  I    + +      F+C +   G P   V W+ +GK L+  
Sbjct: 5506 E----FQV-VEGPPRFIKGISDCYAPIG-TAAYFQCLVR--GSPRPTVYWYKDGK-LVQG 5556

Query: 4020 NRFT-PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
             RFT      G+  +    +   D GEY C ATN  GM E+ A +  T
Sbjct: 5557 RRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 60/228 (26%), Positives = 99/228 (43%), Gaps = 8/228 (3%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS-RFTSIFRFGYI 694
            PP+FI+P+      E     F+  +  +G PT +++W K    IE  + ++      G  
Sbjct: 5379 PPRFIMPICDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE-TLQYI-QQLED 752
            +L + ++ + DS  Y CRAV+  G A  +  L +         ++  + TL  + ++L  
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496

Query: 753  YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
             S Y       +     P+FI+ + D      G  A+F+  +     PT  V WYKDG+ 
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGISDC-YAPIGTAAYFQCLVRGSPRPT--VYWYKDGKL 5553

Query: 813  ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            +            G+ +L I  L   D G Y   A NK G A S A++
Sbjct: 5554 VQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 5601



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 94/396 (23%), Positives = 156/396 (39%), Gaps = 52/396 (13%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            ++   V E  +A  E +     +  +KWY  +  IK     Q     TK  L+I +    
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2510

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D   +  +     G  + + NL VE K +  RG           +++  T  Q V  + +
Sbjct: 2511 DEGPYKLIV----GRVETNCNLSVE-KIKIIRG----------LRDLTCTETQNVVFEVE 2555

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            ++ +  IDV W    K+++P  + KI      Y L +L     D GKY       AGE  
Sbjct: 2556 LSHSG-IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFY----AGENI 2610

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               +  V                 A   I +PL D+ VAE Q   F C+ V  P    +W
Sbjct: 2611 TSGKLTV-----------------AGGAISKPLTDQTVAESQEAVFECE-VANPDSKGEW 2652

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  K +  +   +      +  L I+    +D G+Y    Y  A   T +AKLKV    
Sbjct: 2653 LRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY---TYKVATSKT-SAKLKV---- 2704

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
              + +     L+++ V E Q A F  ++T      +QW++ G ++     + +  +G   
Sbjct: 2705 --EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIY 2762

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             L I N    D   +  R     G++  SA+L V++
Sbjct: 2763 SLRIKNCAIVDESVYGFR----LGRLGASARLHVET 2794



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 66/258 (25%), Positives = 108/258 (41%), Gaps = 17/258 (6%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            +++ EG     E  +      T  V W ++   +E+S      F  G   L I+     D
Sbjct: 952  VTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAED 1009

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ---HPGGLEKIQYLEDASRY---SKR 1032
            +G +TC A N  G  +TS  L +   ++   E+         E+ +++E        +  
Sbjct: 1010 SGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSL 1069

Query: 1033 TEEEVKITQK--PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN 1090
            TEE+    +   P F+       K+VEG S  F  +V    +    V W  +G  +T+  
Sbjct: 1070 TEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1126

Query: 1091 RIQTYHD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
            R +  ++   G   L I+   A+D+G YT+V RN  GE   SAS+  E    +   S   
Sbjct: 1127 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQE 1186

Query: 1149 GLYEK--TRHIEESKFVE 1164
             LY+   T  ++E K  E
Sbjct: 1187 MLYQTQVTAFVQEPKVGE 1204



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 166/768 (21%), Positives = 293/768 (38%), Gaps = 65/768 (8%)

Query: 3675 LEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
            LEE   ++  + I + +     F + IK N  + EG  V F C++   G P  +I W+ +
Sbjct: 1271 LEEDGEEKMAVDISESEAVESGFDLRIK-NYRILEGMGVTFHCKMS--GYPLPKIAWYKD 1327

Query: 3735 GRPFATGSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
            G+    G R     L D G  +L I  +   D G YT  A+N  G+A  + K+       
Sbjct: 1328 GKRIKHGERYQMDFLQD-GRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAP 1386

Query: 3793 IVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECR 3852
            +   + +P      +I+ L    +S +P         P  ++  +      S G R E  
Sbjct: 1387 LGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEET 1446

Query: 3853 VEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
             E + +   +  +                +D+  V   +   +    G+ I   VND+  
Sbjct: 1447 DESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQI---VNDYTH 1503

Query: 3913 DFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQP 3972
               K  I       +I+    P        + Q  A   + +  V LT +    V+ +  
Sbjct: 1504 ---KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRA--GRSSISVILTVE---AVEHQVK 1555

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLL-HKNRFTPIYDF-GY 4030
            P FV ++++       E ++ E ++   G+PN  + W  N   ++ HK     I    G 
Sbjct: 1556 PMFVEKLKNVNI---KEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE 1612

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT---GKPGIVYDSQLPKHMKSIEKI 4087
             A+       +DS  Y   A N  G D T+  +       +P       +P+     ++I
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 4088 R--EME-ASWQVTPEQVVE----ESKARCPPVFVSLPDAVTVEEGEWARFCCRVT--GHP 4138
               E+E    +   EQ  E    + + +  P F     ++ ++    A F CR+T  G P
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDP 1732

Query: 4139 KPRVMWLLNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXL 4197
               V WL +G  +   +R ++  + G    D       D+G I                L
Sbjct: 1733 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1792

Query: 4198 KVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGV-IDHRPELKPK 4256
             V     D + +++ +  P  +     QR E ELE+   E  +    GV  D + + KP 
Sbjct: 1793 IV----KDEKSLVEESQLP--EGRKGLQRIE-ELERMAHEGAL---TGVTTDQKEKQKPD 1842

Query: 4257 VIKEPE----TEWQQSVKRKKNEEY-YNKLQELENEQVIKES---RLR-ESTHQYAIPGD 4307
            ++  PE     E + +  R +   Y   K+    N Q+I++S   R+R +  H   I   
Sbjct: 1843 IVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDC 1902

Query: 4308 KVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQ 4367
            K       K  A+  E  ++   ++  Q+ +   +   R P+P        E HV +  +
Sbjct: 1903 KSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPR------PEFHVHEPGK 1956

Query: 4368 TQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK 4415
             Q EV   +++ R + +TET E+  K +  ER+    V      + +K
Sbjct: 1957 LQFEV---QKVDRPVDTTETKEVV-KLKRAERITHEKVPEESEELRSK 2000



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 63/230 (27%), Positives = 100/230 (43%), Gaps = 9/230 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYV 967
            P F  PI D   I E   A F+  +  IG  T  V+W K+   +E  + +       G  
Sbjct: 5380 PRFIMPICD-FKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK--DIIAESQHPGGLEKIQYLED 1025
             L I++V + D+  Y CRA N +G+A     LT+   +   +IA+         ++ L  
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496

Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQ 1085
             S Y+    E   +   PRF+  +      + G +A+F+  V  +     TV WY +GK 
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLV--RGSPRPTVYWYKDGKL 5553

Query: 1086 ITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +            G+  L I S+   D G Y  VA N +G A+  A++T+
Sbjct: 5554 VQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 109/422 (25%), Positives = 161/422 (38%), Gaps = 72/422 (17%)

Query: 2204 HRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFE 2263
            HR  I +T+  +  E          S  + V  P+  PP+ + EL+  T V  GK A F 
Sbjct: 3203 HRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPE--PPQVLQELQPVT-VQSGKPARF- 3258

Query: 2264 CQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINAL 2323
            C V     P  +I +Y   + L +  +     D    +L +    PEDA  Y+ +A N  
Sbjct: 3259 CAVISGR-PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 3317

Query: 2324 GHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQ 2383
            G  T++ S++V            PE +   +E+        P  P       P    PLQ
Sbjct: 3318 GVATTSASLSVEV----------PEVVSPDQEM--------PVYP-------PAIITPLQ 3352

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            +     EGQ A F CR   V    LKV W+  +K I+ S     T       + I+    
Sbjct: 3353 DTVT-SEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 3408

Query: 2444 EDEGVYMCRASNLLGEXXXXXXXXXXXXXXI---QLETQHPEGMKKI-QKLEQPHERR-- 2497
            EDEG Y   ASN +G+              I   ++E +    MK++  + E  H  R  
Sbjct: 3409 EDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDT 3468

Query: 2498 ------SEEPDRE-------------------FEKPIFTQVLTGPSELWEGQHAHYEARV 2532
                  SE+ D +                   + KP FTQ LT    L EG+   +  R+
Sbjct: 3469 RDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVL-EGEPVVFTCRL 3527

Query: 2533 VPVGDPSLRFEWYINGVELKMGSR--FRTTHDFGF--VTLDINSVVANDAGLYMCKAINR 2588
            +    P +   W+ N   +  G R   +   D      +L+I  V   D+G Y   AIN 
Sbjct: 3528 IACPTPEM--TWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINS 3585

Query: 2589 AG 2590
             G
Sbjct: 3586 EG 3587



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 60/237 (25%), Positives = 91/237 (38%), Gaps = 16/237 (6%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
            EG +   E  ++    PT  V WY++   I +S      F  G   L I    AED+G +
Sbjct: 956  EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013

Query: 844  TVRAVNKLGEAISTASIRVAA------RSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXX 897
            T  AVN+ G   ++  + V         +T   +    E++R++E               
Sbjct: 1014 TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1073

Query: 898  XXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR 957
                 P     P F T    Q  + EGG   F  ++   G+    V W K G P+    R
Sbjct: 1074 AG---PGEPAAPYFITKPVVQ-KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYR 1127

Query: 958  ITTFFN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
                +N   G   L I      DAG YT    N  G+ + SA+L      +++ +SQ
Sbjct: 1128 YKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 67/235 (28%), Positives = 96/235 (40%), Gaps = 16/235 (6%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI--NDFGF 3614
            PP F     D  + ENS A F+C +I +   +  V+W+      +    +K +   + G 
Sbjct: 5379 PPRFIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYM-CIEPDNIKYVISEEKGS 5435

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ--GIILEPQLPSHFKSGTESI 3672
              L+I  V   D+  Y C+A N  GEA     L +   +   +I +    +      E +
Sbjct: 5436 HTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELV 5495

Query: 3673 QKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWF 3732
             K   T    E   +E     PPRF   I D    P G   +F C V   G P   + W+
Sbjct: 5496 LKSNYTDSFFEFQVVE----GPPRFIKGISDCY-APIGTAAYFQCLVR--GSPRPTVYWY 5548

Query: 3733 HNGRPFATGSRVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             +G+    G R        GF  L I  +   D GEY C ATNK G A + A +T
Sbjct: 5549 KDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALT 5602



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 43/147 (29%), Positives = 73/147 (49%), Gaps = 12/147 (8%)

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQK-P 272
            D  S + F+ +  E + + +    +S   R+V  SD  I+ E         PPK+ Q+ P
Sbjct: 4117 DKESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSD--ITNE---------PPKMLQEMP 4165

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
            ++++ +EG     +  +SG P+P VTWF+NG  L  + K +    +    L +++    D
Sbjct: 4166 KHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQD 4225

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPT 359
            SG Y  +AEN +G + +   L VE  T
Sbjct: 4226 SGKYKCVAENNSGAVESVSDLTVEPVT 4252



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 10/203 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVY 3101
            T + P FT   + +V + EG  A +EA +  +G     + WF +G+ I  S    ++  +
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
            + G   L I      +SG YS +ATN  GQA  + +L  + K++   P F   +Q++  +
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMT-V 115

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            + G     +  V  +  P +K  +Y +G  ++ S   +   +     L IA     DSG 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGT 173

Query: 3222 YVCRAYNKYGEDFTRATINCYGK 3244
            Y   A N  G   + A +   G+
Sbjct: 174  YSVNATNSVGRATSTAELLVQGE 196



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 35/116 (30%), Positives = 55/116 (47%)

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            V +    +VT  A++             ++ L+++ V EG+    +  I+    PT+ W 
Sbjct: 918  VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 977

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            RE   I  + DFQ+  +   A L+I   + ED+G FTC A   AG V TS  L V+
Sbjct: 978  REDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 92/397 (23%), Positives = 156/397 (39%), Gaps = 53/397 (13%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            +K +    V E ++A FE E    P    +W R+   +  + + +  +   K  LII   
Sbjct: 2623 SKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAAT 2681

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             ++D   +      +  T+K SA L VE  +              T +N+ VT  Q    
Sbjct: 2682 KLDDIGEYTY----KVATSKTSAKLKVEAVK-----------IKKTLKNLTVTETQDAVF 2726

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              ++T      V W+KNG  ++ + +  I  +   Y+L I      D   Y         
Sbjct: 2727 TVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGA 2786

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR   E V                     +II+  KD    E   + F   +    +P 
Sbjct: 2787 SARLHVETV---------------------KIIKKPKDVTALENATVAFEVSVSHDTVP- 2824

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            V+W+  +  IKPS   ++      + L +    P D G+Y  V     G++   AKL V 
Sbjct: 2825 VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFV- 2879

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
                 + L     +++I V E + A F+ +++    P++ WL+ G  I  +  F+++ +G
Sbjct: 2880 -----ETLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG 2933

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                L+I NT  ED+  +    T   G  + SA L V
Sbjct: 2934 KLHQLIIMNTSTEDSAEY----TFVCGNDQVSATLTV 2966



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 89/331 (26%), Positives = 136/331 (41%), Gaps = 32/331 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI---EASHRIRTVYAF-----GMVV-LEI 3110
            + E  + H  +S  P+  Q +V+E   + K +   E   +I TV  F      M+V L++
Sbjct: 5291 VMEFDLEHTTSSRTPS-PQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPDHKSMIVSLDV 5349

Query: 3111 LGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            L     D    S    +K    E+ + LE  +      PRF   I + + + +   A F+
Sbjct: 5350 LPFNFVDPNMDSREGEDK----ELKIDLEVFE----MPPRFIMPICDFK-IPENSDAVFK 5400

Query: 3171 CTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNK 3229
            C+V+ +  P++K  WY     +        +S+  G   L I      DS  Y CRA N 
Sbjct: 5401 CSVIGIPTPEVK--WYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNC 5458

Query: 3230 YGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE----PPKFI 3285
             GE   R  +   G   ++    +   +     +E L      T S    +    PP+FI
Sbjct: 5459 VGEAICRGFLTM-GDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFI 5517

Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD-FGIVILDI 3344
              I D    + G +A+F+  LV    P   V W+ +GK L  G R+       G   L I
Sbjct: 5518 KGISDCYAPI-GTAAYFQC-LVR-GSPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFI 5573

Query: 3345 LYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
                + + GEY CVATNK G   + A L  T
Sbjct: 5574 TSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 78/342 (22%), Positives = 121/342 (35%), Gaps = 19/342 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN-K 470
            + RV   P P   +   D    D Y  +  V       + IT  T+ +        R  K
Sbjct: 868  ETRVRAEPTPLPQFPFADTP--DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAK 925

Query: 471  SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530
              ETA   R+    +  V  P  V     + V EGE V L     G P+P +TW ++   
Sbjct: 926  VTETA---RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQ 982

Query: 531  IIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQ 590
            I  + + +I    G + L I  A A D+  + C+A N AG+ +T   L           +
Sbjct: 983  IESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL---AVQVSEEFE 1039

Query: 591  KRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAME 650
            K                       +           PGE       P FI        +E
Sbjct: 1040 KETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEP----AAPYFITKPVVQKLVE 1095

Query: 651  GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--RFGYISLDMLSLNIQDSGE 708
            GG + F  ++   G+P   + W K+G  +    R+   +  + G   L +      D+GE
Sbjct: 1096 GGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1153

Query: 709  YTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQL 750
            YT    +  G  ET A   +   A  E   +  + + Y  Q+
Sbjct: 1154 YTIVVRNKHG--ETSASASLLEEADYELLMKSQQEMLYQTQV 1193



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 8/161 (4%)

Query: 357  SPTESYVQDQRSQYITDTQQRETEE-RIE--ISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
            S T + V+++R + +   + + TE  R+   +      P  V   ++  V EG+    +C
Sbjct: 905  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
             ++G P P VTW+  D QI    + +I   +SG   LMI      DSG  TC A N++G 
Sbjct: 965  HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023

Query: 474  TAFQCRL--NVIEKEQVVAPKFVERFSTLNVR--EGEPVVL 510
             +  C L   V E+ +       E+F+T   R  E   VV+
Sbjct: 1024 VSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVM 1064



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 133/626 (21%), Positives = 236/626 (37%), Gaps = 88/626 (14%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+ + +++  TV+  +  RF   +  +  PK  I WY+  +LL +G + +         
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPK--ISWYKEEQLLSTGFKCK--------- 3286

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
                  +  D  EY    +  F ED   A  +C+   D         G+  + A   +E 
Sbjct: 3287 ------FLHDGQEYTLLLIEAFPED--AAVYTCEAKNDY--------GVATTSASLSVEV 3330

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
                   EV   + ++       PP  +T +Q  T   E +  +F+C+   V   ++KV 
Sbjct: 3331 P------EVVSPDQEM----PVYPPAIITPLQD-TVTSEGQPARFQCR---VSGTDLKVS 3376

Query: 4009 WFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W+   K +   +RF  +  F     +     YPED G Y   A+N  G   + A +    
Sbjct: 3377 WYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435

Query: 4068 KPGIVYD---SQLPKHMKSIEKIREMEASWQVT------PEQVVEESKAR---------- 4108
               I+++    ++   MK +    E E S + T       E +  +S A           
Sbjct: 3436 PESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISST 3495

Query: 4109 --CPPVFV-SLPDAVT---VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR--YKLT 4160
               P  F  S    +T   V EGE   F CR+   P P + W  N   I  G R   K  
Sbjct: 3496 SSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAE 3555

Query: 4161 YDGMYH---FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDD--YRGVLKNAPR 4215
             D  +H    +I + +  D+G   ++             L VI +  D  Y   LK A R
Sbjct: 3556 SDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAER 3615

Query: 4216 PWYDETTQYQRTETELE-------KTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQS 4268
               +     +R E  ++         F ++Q ++++G++           K+ +  + + 
Sbjct: 3616 THENVEALVERGEDRIKVDLRFTGSPFNKKQDVEQKGMMRTIHFKTMSSAKKTDYMYDEE 3675

Query: 4269 VKRKKNE--EYYNKLQE-LENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDN 4325
                K++   + N  +  L+ E  +K  RLRE+  +  +   K++    +  ++ R   +
Sbjct: 3676 YLESKSDIRGWLNVGESFLDKETKVKLQRLREA-RKTLMEKKKLSLLDTSSEISSRTFRS 3734

Query: 4326 LDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITST 4385
                +++   R   K+     + + S    H  E  V        ++  + E     TS 
Sbjct: 3735 EASDKDILFSREDMKIRSMSDLAE-SYKVDHSAESIVQNPHALSNQMDQNIESEELPTSF 3793

Query: 4386 ETTEIEHKAQTQERV-VEGPVKPSKP 4410
            +T   E   QT+ R+  E  VK S P
Sbjct: 3794 QTIVDEEIFQTEIRMSQEALVKESLP 3819



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 63/235 (26%), Positives = 99/235 (42%), Gaps = 15/235 (6%)

Query: 2363 KRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-D 2421
            K  +I   V    P F  P+ +   I E   A F C +I  G PT +V+W++    IE D
Sbjct: 5367 KELKIDLEVFEMPPRFIMPICDF-KIPENSDAVFKCSVI--GIPTPEVKWYKEYMCIEPD 5423

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHP 2481
            + +   + + G  ++ I +V   D   Y CRA N +GE                +  +  
Sbjct: 5424 NIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAK-- 5481

Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIF---TQVLTGPSELWE--GQHAHYEARVVPVG 2536
            +    +  L +    +S   D  FE  +     + + G S+ +   G  A+++  V   G
Sbjct: 5482 KSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLV--RG 5539

Query: 2537 DPSLRFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
             P     WY +G +L  G RF       GF  L I S+V +D G Y C A N++G
Sbjct: 5540 SPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 5593



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 56/232 (24%), Positives = 99/232 (42%), Gaps = 7/232 (3%)

Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGS-RFTETN 1630
            EV    P     + + +I E   A F+  +I +   T +V+WY     ++  + ++  + 
Sbjct: 5374 EVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIP--TPEVKWYKEYMCIEPDNIKYVISE 5431

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG-IAIVHSKKSIYLESQHEGALPRL- 1688
              G   L I +    DS TY CRA+N +GEA+  G + +  S+    +  + +  L  L 
Sbjct: 5432 EKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLM 5491

Query: 1689 NQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748
             +L   S Y     + +V+   P F   + D       AA+F+   +  G P+  V W +
Sbjct: 5492 EELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC--LVRGSPRPTVYWYK 5549

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
            +G  ++           G+  L +  +   D G Y C A N+ G A + + L
Sbjct: 5550 DGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 5601



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 82/307 (26%), Positives = 134/307 (43%), Gaps = 46/307 (14%)

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
            ++ K+ E   A F+ ++S  P   V W K+ Q L  +++ +I        L + +T+ SD
Sbjct: 3065 KDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 3123

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
            +G YT++A    G  V++  L VE                D + R  ++ +++ EK  A 
Sbjct: 3124 AGKYTVVA----GGNVSTAKLFVEG--------------RDVRIRSIKKEVQVIEKQRAV 3165

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
               +V +D DV              +   E+ + + +R       HK +V E   H + I
Sbjct: 3166 VEFEVNED-DVDAHWY---------KDGIEINFQVQER-------HKYVV-ERRIHRMFI 3207

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +    SD+G  T VA RN+S  T +   +N  E  QV+     +    + V+ G+P    
Sbjct: 3208 SETRQSDAGEYTFVAGRNRSSVTLY---VNAPEPPQVL-----QELQPVTVQSGKPARFC 3259

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            A   G P P+I+W K+   +    + +   DG   TL +  A   DAA Y C A+N  G 
Sbjct: 3260 AVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGV 3319

Query: 572  TATRARL 578
              T A L
Sbjct: 3320 ATTSASL 3326



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 78/271 (28%), Positives = 115/271 (42%), Gaps = 40/271 (14%)

Query: 625  IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
            + P +E  VYPP   I PL+     EG    F+ R   V    +K+ W    + I+  SR
Sbjct: 3334 VSPDQEMPVYPPA-IITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIK-PSR 3388

Query: 685  FTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATG-VAET--------KAVLHVTPRATI 734
            F  + +F     L++     +D G YT  A +A G V+ T        +++LH      I
Sbjct: 3389 FFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEI 3448

Query: 735  ER---------TSQHPE--TLQYIQQLEDYS----KYQHQESIEEQTSQRPQFIRP--LQ 777
            E           S+H E  T       ED        +   S    TS  P++ +P   Q
Sbjct: 3449 EMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQ 3508

Query: 778  DL--GELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI-TASSRI---TSIFNFGYVSLN 831
             L    + EG    F  +L  ++ PT  + W+ + RPI T   RI    S  +    SL 
Sbjct: 3509 KLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLE 3566

Query: 832  IMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            I  ++  D+GSY + A+N  G A STAS+ V
Sbjct: 3567 IKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 35/105 (33%), Positives = 56/105 (53%), Gaps = 2/105 (1%)

Query: 255  EIDRS-LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE 313
            E D S L  +  P    KP + K  EG  A+F +++ G P P   WF +GQ+++N   H+
Sbjct: 1445 ETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK 1504

Query: 314  IITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            ++   + T +L +     SDSG +T++A+N  G    S  L VE+
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1549



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 60/233 (25%), Positives = 101/233 (43%), Gaps = 22/233 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH-RFKTTYDFGYVA 2036
            P+F  PI + ++ E      + ++  +  PT  V+WY     ++  + ++  + + G   
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYMCIEPDNIKYVISEEKGSHT 5437

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAV-----TTSSVKVDA----KSGLYLDTLDEQRLKK 2087
            L I      D+ TY C+A N VGEA+     T    ++ A    KS + L +L E+ + K
Sbjct: 5438 LKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLK 5497

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                + +   + +E       P F+  ++       G  A+F+C V     P  T+ W+ 
Sbjct: 5498 SNYTDSFFEFQVVEGP-----PRFIKGISDC-YAPIGTAAYFQCLVR--GSPRPTVYWYK 5549

Query: 2148 NGQKIRAGHRYRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
            +G K+  G R+       G+  L I      D G Y C ATNK G A +   L
Sbjct: 5550 DG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 5601



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 13/141 (9%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFF 962
            +TQ P F  P++  + + EG  A FEA +   G     V W +DG+ +  S+   +   F
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            + G   LTI +VT  ++G Y+ +A N  GQAT++A L +       AE+  P  ++++Q 
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK------AETAPPNFVQRLQS 112

Query: 1023 LEDASRYSKRTEEEVKITQKP 1043
            +    R   +   +V++T  P
Sbjct: 113  M--TVRQGSQVRLQVRVTGIP 131



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 99/418 (23%), Positives = 158/418 (37%), Gaps = 67/418 (16%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            +Y   A R        V   + P+ L  L+    +  G+ A F A +  +      + WY
Sbjct: 3217 EYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVT-VQSGKPARFCAVISGRPQ--PKISWY 3273

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
               + +++  + +  HD     L +     ED+ VYT  A+N  G A  SAS++VE    
Sbjct: 3274 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3333

Query: 1141 IDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECR 1200
            +                            +E+    P  + PL +    SEG+    +CR
Sbjct: 3334 VSPD-------------------------QEMPVYPPAIITPLQDTV-TSEGQPARFQCR 3367

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
            +       ++V W+   + +     F+         L+I  A   D G YT  A N +G 
Sbjct: 3368 VS---GTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ 3424

Query: 1261 AHTSAIVRVIERSDIVTDT-QNEQAIEQIQLL-----EDAARRTKQV---REDIT--VMQ 1309
              ++A + +     I+ +  + E  +E  +L      E + R T+      EDI    M 
Sbjct: 3425 VSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMA 3484

Query: 1310 A------------------PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK 1351
            A                  P F++ L     +EG  V   CRL  +   T  + WF N +
Sbjct: 3485 AKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRL--IACPTPEMTWFHNNR 3542

Query: 1352 PIKTGHRFRPAYEFDY----VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            PI TG R     E D      +L++  V   DSG Y   A N  G A ++ +L VI K
Sbjct: 3543 PIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 3/115 (2%)

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
            Q  ST   + + + +PP FV  L+  T V +G     + +V  +  P   ++FY +G  +
Sbjct: 88   QATSTAELLVKAETAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEI 144

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
            QS+  F I+ +    SL I    PED+G YSV A N++G  TS   + V  +  +
Sbjct: 145  QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 2/106 (1%)

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            + PP+     +NV V  G+ V L+  ++G     V W +   +++  I  +I  + G   
Sbjct: 940  VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 999

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
            L+I EA+ +DSG++ C A+N AG       C +++  +++  K  T
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTV--STSCYLAVQVSEEFEKETT 1043



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 105/508 (20%), Positives = 194/508 (38%), Gaps = 58/508 (11%)

Query: 4306 GDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQ 4365
            G+ +TS  +  +     +   DQT   +++ V +     P      E    GK + +   
Sbjct: 2607 GENITSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANP--DSKGEWLRDGKHLPLTNN 2664

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
             +++ +    + I       +  E  +K  T +   +  V+  K     K ++   V E 
Sbjct: 2665 IRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVK---IKKTLKNLTVTET 2721

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            + A F VE     +  ++W +    ++++  + I    T   L I+   + D +V+    
Sbjct: 2722 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGF-- 2779

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
              R G    SA L VE  +      I  P      +N  V     V  DT       + V
Sbjct: 2780 --RLGRLGASARLHVETVKI-----IKKPKDVTALENATVAFEVSVSHDT-------VPV 2825

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W     +++P  +++++ E   + L++    P D+G+Y  V     G+  C A+  V  
Sbjct: 2826 KWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVE- 2880

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                               I + +K+  V E +   F C++    +P++ W K    I+ 
Sbjct: 2881 ----------------TLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEM 2923

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+ F++      + L I     ED  +Y  V     G   V+A L VT       +   +
Sbjct: 2924 SEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGNDQVSATLTVTP------IMITS 2973

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             L+DI   E     F+  +  +   + +WL+ G  I  T   QM  +     L I N + 
Sbjct: 2974 MLKDINAEEKDTITFEVTVNYE-GISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHF 3032

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             D   +    T  AG+  ++A L V+++
Sbjct: 3033 GDAADY----TFVAGKATSTATLYVEAR 3056



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIF 823
           T+Q P F +PLQ +  L EG  A FEA ++    P   V W++DG+ I+ S+   +   F
Sbjct: 2   TTQAPTFTQPLQSVVVL-EGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           + G   L I  +   ++G Y+++A N  G+A STA + V A +
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 4722 PALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMIHEGNNAVL 4778
            P  T PL+ +VV EG  A F+  I+    P + W R+G +I  +  P  Q+      A L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             I    + ++G ++ +AT  +GQ  ++A+L+VK++T
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 60/232 (25%), Positives = 96/232 (41%), Gaps = 12/232 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH-RYRTTHDFGYV 2167
            P F+  +   + + E   A F+C V  I  P   + W+     I   + +Y  + + G  
Sbjct: 5380 PRFIMPICDFK-IPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR--NIILDTQHPNGLEKIRQLEA 2225
             L I      DS TY C+A N +GEA+    L +       +I           + +L  
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496

Query: 2226 QGHSTRIEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKA 2284
            + + T    E   +  PPRF+  +    +   G  A+F+C V     P   + +Y +GK 
Sbjct: 5497 KSNYTDSFFEFQVVEGPPRFIKGI-SDCYAPIGTAAYFQCLVR--GSPRPTVYWYKDGKL 5553

Query: 2285 LQSAARFHI-TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
            +Q   RF +     G+ +L I   V  D GEY   A N  G   S  ++T+T
Sbjct: 5554 VQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++  V +G  V L+  +T +  PT  V++Y +G  +Q    F+ + +    +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             I  AY ED+GTY   ATN+VG A +T+ + V  +
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765
            TQAP FT P++ + V E   A FEA +   G P   V W R+G  I  S        F  
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSD 60

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            G   L +  V   +SG Y+ +A N  G+A +++ L V+++ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 91/406 (22%), Positives = 159/406 (39%), Gaps = 71/406 (17%)

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            ++T    +  PP+       + +     A F C +I       ++ W+   + L TG + 
Sbjct: 3228 SVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQP-KISWYKEEQLLSTGFKC 3285

Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            K ++D     L +   +  DA +YTC+A N +G AT S  L V+  + +  + ++P +  
Sbjct: 3286 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVY-- 3343

Query: 3667 SGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT 3726
                 I  L++T      +T E +   P RF                   CR   V    
Sbjct: 3344 -PPAIITPLQDT------VTSEGQ---PARF------------------QCR---VSGTD 3372

Query: 3727 MRIDWFHNGRPFATGSRVHTLNDF-GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +++ W+   +     SR   +  F     L+I   Y  D G YT  A+N  G  ++TA +
Sbjct: 3373 LKVSWYSKDKKIKP-SRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3431

Query: 3786 TCSAKRDIV---LESQLPQGM-------SGEKIKELERGRISDAPKEEPIVSTPPKFITQ 3835
            +  A   I+   +E ++   M         E  +   R   SD+   +       ++ ++
Sbjct: 3432 SLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASR 3491

Query: 3836 IKSHT------------------VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
            I S +                  V E E V F CR+     P++   W+ N + +P+G R
Sbjct: 3492 ISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEM--TWFHNNRPIPTGLR 3549

Query: 3878 --YRTVYDMGF--VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               +   D+     SL+I  V   DSG Y   A+N  G   + A++
Sbjct: 3550 RIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASL 3595



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 51/238 (21%), Positives = 105/238 (44%), Gaps = 10/238 (4%)

Query: 2224 EAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGK 2283
            E +    +I++E  ++ PPRF+  +     + E   A F+C V  +  P   +++Y    
Sbjct: 5363 EGEDKELKIDLEVFEM-PPRFIMPICDFK-IPENSDAVFKCSVIGIPTPE--VKWYKEYM 5418

Query: 2284 ALQ-SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAISMTVTAKGSI 2340
             ++    ++ I+ + G  +L I++    D+  Y  +A+N +G   C   ++M  +   ++
Sbjct: 5419 CIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAV 5478

Query: 2341 ISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRL 2400
            I++  +      + EL     +        V    P F + + +      G  A+F C  
Sbjct: 5479 IAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDC-YAPIGTAAYFQC-- 5535

Query: 2401 IPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            +  G P   V W+++ KL++      +    G+ ++ I+ +   DEG Y C A+N  G
Sbjct: 5536 LVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 5593



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 62/232 (26%), Positives = 102/232 (43%), Gaps = 16/232 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYVSLD 2834
            FI  + +    E  +  F+C+V     PT +++W+     + P   +Y  + +    +L 
Sbjct: 5382 FIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I +    DS  Y C+A N  G A   G L   GD  I F     + K  L ++   EE  
Sbjct: 5440 IRNVCLSDSATYRCRAVNCVGEAICRGFLTM-GDSEI-FAVIAKKSKVTLSSL--MEELV 5495

Query: 2895 LAKGRRPSVPDTEYPK--PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            L      S  + +  +  P +I  I+  +  + G   + +  V  +  P   + WY +GK
Sbjct: 5496 LKSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLV--RGSPRPTVYWYKDGK 5552

Query: 2953 VLEQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRG--EAFTSSTV 3001
            ++ QG RF +  S  GF  L +  + + D G Y C A NK G  E+F + T+
Sbjct: 5553 LV-QGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 4/137 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH--EIITTHNHTTL 323
           P   Q  ++  + EG+ A F+  +SG P P V+WF++GQ +  S     +I  +     L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +    K++SG Y+L A N +G   ++  L V++ T      QR Q +T  Q   ++ R+
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQ--GSQVRL 123

Query: 384 EISEKALAPQFVKVCQD 400
           ++    +    VK  +D
Sbjct: 124 QVRVTGIPTPVVKFYRD 140



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 30/98 (30%), Positives = 55/98 (56%), Gaps = 2/98 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L ++   +G+ V L+ R+   G  T  V+++ +G  I++   F+ + E D  +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
             +   YPEDSG Y+  ATN +G A ++  L V  ++++
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 12/160 (7%)

Query: 1792 GEAVTSSTL------FVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQA 1843
            G+ +++STL      F   +A L + +  +  S    ++    S +     ++ V    A
Sbjct: 43   GQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102

Query: 1844 P-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            P  F+ +L   T + +G     + R+   P P   V++Y +G  +QS   ++ S +    
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +L I   Y EDSG Y+  A N++G+A S+  L VQ +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 58/228 (25%), Positives = 97/228 (42%), Gaps = 14/228 (6%)

Query: 352  YLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRF 411
            +L++ +   S  +D     + D   + T + I   E A+  +FVK  QD +V E      
Sbjct: 2230 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIV--EGAVV-EFVKELQDIEVPESYSGEL 2286

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V+     E  W+ ND +++ +  + I  +  G   L + +VT  D G  + V   K 
Sbjct: 2287 ECIVSPENI-EGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFVIDGKK 2344

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
                  C+L +  K + +A   ++  S   V EG+ V L  + V   +    W KDG  +
Sbjct: 2345 TT----CKLKM--KPRPIA--ILQGLSDQKVCEGDIVQLEVK-VSLESVEGVWMKDGQEV 2395

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             P+  + I  D  +  L I      DA  Y  T   +  ST+ R  +Y
Sbjct: 2396 QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2443



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 82/351 (23%), Positives = 132/351 (37%), Gaps = 50/351 (14%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP      ++   ++G  A+F+ ++ G    V SW  K   +     + M   E T    
Sbjct: 3344 PPAIITPLQDTVTSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFEDT--YQ 3400

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I +  P DEG YT  A N  G+   +  +  E                   E++ H+ 
Sbjct: 3401 LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA-----------------PESILHER 3443

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
                    ++     K  ++ G    S  D + D F      ++  +    KRY      
Sbjct: 3444 I------EQEIEMEMKELFSEGESEHSERDTR-DAFSDS--EDIDHKSMAAKRYAS---- 3490

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
            +IS+    S      P   QK     + EG    F  +L   P P +TWF N  R I + 
Sbjct: 3491 RISST--SSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNN-RPIPTG 3547

Query: 311  KHEIITT-----HNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV--ESPTESYV 363
               II       H+ ++L ++  Q  DSG Y LLA N  G   ++  L V  +   E Y+
Sbjct: 3548 LRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYL 3607

Query: 364  Q----DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410
            +     +R+    +      E+RI++  +     F K    +DV +  M R
Sbjct: 3608 EFLKRAERTHENVEALVERGEDRIKVDLRFTGSPFNK---KQDVEQKGMMR 3655



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 61/237 (25%), Positives = 96/237 (40%), Gaps = 14/237 (5%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
            K+  I  E   + PRF+  P     + E     F+C +  +    +K  W+K    +   
Sbjct: 5367 KELKIDLEVFEMPPRFIM-PICDFKIPENSDAVFKCSVIGIPTPEVK--WYKEYMCIEPD 5423

Query: 1491 H-RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR-LTCRSTTDIVRSTQN 1548
            + ++    + G   L I ++   DS  Y CRAVN VG  E  CR       ++I      
Sbjct: 5424 NIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVG--EAICRGFLTMGDSEIFAVIAK 5481

Query: 1549 EAGLEQIQVLED---RSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVS 1605
            ++ +    ++E+   +S Y  +    +V    P     + +     G  A+F+   +   
Sbjct: 5482 KSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQ--CLVRG 5539

Query: 1606 DATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
                 V WY + K L  G RFT E +  GF  L I S +  D G Y C A N  G A
Sbjct: 5540 SPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 5595



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 93/202 (46%), Gaps = 33/202 (16%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK-HEIITTHNHTTLR 324
            PKI ++ ++  + +G+DA F+V++ G P P   W+KNG ++  S++ +      N   L 
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +R+    DS    + A N          +A E+ + +++  Q  Q IT TQ+ +      
Sbjct: 2138 IRDVTAEDSASIMVKAIN----------IAGETSSHAFLLVQAKQLITFTQELQD----- 2182

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                        V +++D     M  F+C  T  P+ +V W+ +  ++ +   ++ + ++
Sbjct: 2183 -----------VVAKEKDT----MATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSD 2225

Query: 445  SGNHALMITNVTLSDSGVVTCV 466
               H L I  +  SD+   +CV
Sbjct: 2226 RKVHFLSILTIDTSDAEDYSCV 2247



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +  L  +  + G    F C V   R P  KI W+   + L +G + K  HD    +L + 
Sbjct: 3242 LQELQPVTVQSGKPARF-CAVISGR-PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI 3299

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSL 2863
              + ED+ +YTC+A N  G ATTS SL
Sbjct: 3300 EAFPEDAAVYTCEAKNDYGVATTSASL 3326



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 12/225 (5%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFRTFCDFGFV 3478
            P F +P+ + + + E  +A F+  +     P +K  WY     ++  + ++    + G  
Sbjct: 5380 PRFIMPICDFK-IPENSDAVFKCSVIGIPTPEVK--WYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
             L+I      DS  Y CRA N  GEA+    + +       + ++  K    ++ +   L
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 5496

Query: 3539 EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGK 3598
            +  S   D+         PP F    SD      ++A+F+C  +        V W+ +GK
Sbjct: 5497 K--SNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC--LVRGSPRPTVYWYKDGK 5552

Query: 3599 PLLTGSRVKTINDFG--FVILEIGGVYQRDAGLYTCKATNRHGEA 3641
             L+ G R  T+ + G  F  L I  + + D G Y C ATN+ G A
Sbjct: 5553 -LVQGRRF-TVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 5595



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 70/271 (25%), Positives = 100/271 (36%), Gaps = 31/271 (11%)

Query: 2339 SIISESQRPEGLEKI--RELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTAH 2395
            SI   + R E  E +  RE +  E  + P   E PVT   P     L+N+  I EG++  
Sbjct: 905  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTP--PTLVSGLKNVTVI-EGESVT 961

Query: 2396 FDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
             +C +     PT  V W+R +  IE S     T   G   + I     ED G + C A N
Sbjct: 962  LECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVN 1019

Query: 2456 LLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLT 2515
              G                + ET         +K     +R  E  D        T+   
Sbjct: 1020 EAGTVSTSCYLAVQVSEEFEKET-----TAVTEKFTTEEKRFVESRDVVMTDTSLTEEQA 1074

Query: 2516 GPSE--------------LWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            GP E              L EG    +  +V   G+P     W  +GV L  G R++ ++
Sbjct: 1075 GPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSY 1132

Query: 2562 D--FGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +   G   L I+   A+DAG Y     N+ G
Sbjct: 1133 NKQTGECKLVISMTFADDAGEYTIVVRNKHG 1163



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 4737 PAQFKTQITSKIKPT--IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            PA F+ ++T    PT  ++WL +G  +      +MI+E     L  G  Y  D+G  TCR
Sbjct: 1719 PAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCR 1778

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            AT   G   TSA L+VK +
Sbjct: 1779 ATNKYGTDHTSATLIVKDE 1797



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 59/251 (23%), Positives = 92/251 (36%), Gaps = 38/251 (15%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   Q LQ +  +Q G+ A F C +I  G P  K+ W++ E+L+    +    HD    +
Sbjct: 3239 PQVLQELQPV-TVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495
            + +     ED  VY C A N  G                 L  + PE +           
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSAS----------LSVEVPEVVS---------- 3335

Query: 2496 RRSEEPDREFEKPIFTQVLTGPSE---LWEGQHAHYEARVVPVGDPSLRFEWYINGVELK 2552
                 PD+E   P++   +  P +     EGQ A ++ RV       L+  WY    ++K
Sbjct: 3336 -----PDQEM--PVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIK 3385

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMR 2612
                FR T       L+I      D G Y   A N  G               I+ + + 
Sbjct: 3386 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIE 3445

Query: 2613 PESWEQIQLKE 2623
             E   ++++KE
Sbjct: 3446 QEI--EMEMKE 3454



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 5/104 (4%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F++  + ++V EG    F C   G P P VTW+ ND  I    N   +++   N++++
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPI--PRNQNFIIHSLENYSIL 4001

Query: 452  -ITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQVVAPK 492
             +++V   + G +TCV  N+ G  +T    ++   +K  V A K
Sbjct: 4002 TLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHK 4045



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 7/117 (5%)

Query: 1289 QLLEDAARRTKQVREDITVMQAPQ--FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEW 1346
            +LLE+       V  DI+  +A +  F   + N   +EG  V   C++   G    ++ W
Sbjct: 1269 ELLEEDGEEKMAV--DISESEAVESGFDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAW 1324

Query: 1347 FCNGKPIKTGHRFRPAYEFD-YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            + +GK IK G R++  +  D   +L +  V PED G+YT  A+N  G A+ S  L V
Sbjct: 1325 YKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1381



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 7/86 (8%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF---GFAALDILTVYG 1911
            ++ EG    + C++  YP P  ++ WY +GK ++ G RY+   DF   G A+L I  V  
Sbjct: 1301 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLP 1356

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            ED G YT  A N  G A+ S +L V+
Sbjct: 1357 EDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 96/395 (24%), Positives = 167/395 (42%), Gaps = 34/395 (8%)

Query: 1424 LEDTSRYK-KTDIIDESVTIKPRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLK-VE 1479
            L+D   Y  K      S  +K   V   K+++N  V E Q   F  +L   T  N+K V+
Sbjct: 2683 LDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL---THPNVKGVQ 2739

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W KNG  +    ++         +L I +    D  +Y  R    +G    S RL    T
Sbjct: 2740 WIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFR----LGRLGASARLHVE-T 2794

Query: 1540 TDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599
              I++  ++   LE   V  + S  H T  V        I   S K+  + E +      
Sbjct: 2795 VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEI-KPSDKHRLVSERKVHKLML 2853

Query: 1600 RLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPED-SGTYTCRA--I 1655
            + I  SDA    E+      L+  ++ F ET +      +I   +PE  + ++ C     
Sbjct: 2854 QNISPSDAG---EYTAVVGQLECKAKLFVETLHITKTMKNIE--VPETKTASFECEVSHF 2908

Query: 1656 NALGEAVTSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV---ITQAP 1711
            N     + +G+ I  S+K  I ++ +    +      ED+++Y      D+V   +T  P
Sbjct: 2909 NVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTP 2968

Query: 1712 VF-TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            +  T  +KDI   E     FE   + V    +  +WL+NGV I+++++          +L
Sbjct: 2969 IMITSMLKDINAEEKDTITFE---VTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSL 3025

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            N++ V+  D+  YT  A    G+A +++TL+V+++
Sbjct: 3026 NIRNVHFGDAADYTFVA----GKATSTATLYVEAR 3056



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 2/130 (1%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           Q   T E +  +E A  P FV+  Q   V +G   R   RVTG P P V ++ +  +I+ 
Sbjct: 88  QATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             + +I   E   ++L+I      DSG  +  A N  G       L V  +E+V A K  
Sbjct: 147 SLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTK 205

Query: 495 ERFSTLNVRE 504
              ST  + E
Sbjct: 206 TIVSTAQISE 215



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F++ LQ +  +++G     + ++T +  PT  V++Y+DG  I +S            S
Sbjct: 104 PNFVQRLQSM-TVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I     ED+G+Y+V A N +G A STA + V     V A
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPA 201



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L S+  +++G +   + RV  I  P   + ++ +G +I++   ++ + +    +
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
            L I   Y EDSGTY   ATN +G A +T  L V G   +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 4/114 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYRTSNDFG 1900
            +AP+   ++   T + +G  AH+  R+   PDP    EWY NG K+ +S   Y    +  
Sbjct: 2076 EAPKIFERIQSQT-VGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERSDRIYWYWPEDN 2132

Query: 1901 FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
               L I  V  EDS     KAIN  G+  S   L VQ+K+ I    + +  + K
Sbjct: 2133 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2186



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 35/166 (21%), Positives = 69/166 (41%), Gaps = 3/166 (1%)

Query: 1775 VNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRRE 1834
            + P  S ++      E  E + S  +       LQL +       K +Q E++ R+    
Sbjct: 3875 ITPHASESFGTLVNVEESEEIASERIKKDDLRELQLSASTRIDEFKTEQKEENMRFFENS 3934

Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
              +      P F+ ++    ++ EG S ++ C  + YP P   V WY N   +     + 
Sbjct: 3935 FRKRPQRCPPSFLQEIESQ-EVYEGDSCNFVCHFQGYPQPI--VTWYNNDMPIPRNQNFI 3991

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
              +   ++ L + +V+ ++ G  TC   N  G   ++  L V++K+
Sbjct: 3992 IHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQ 4037



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 2/125 (1%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +PP   Q+ ++  +++G+  + QV+++G P P V ++++G  + +S   +I    +  +L
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +      DSG Y++ A N  G   ++  L V+   E  V  ++++ I  T Q     + 
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG--EEEVPAKKTKTIVSTAQISESRQT 219

Query: 384 EISEK 388
            I +K
Sbjct: 220 RIEKK 224



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 59/243 (24%), Positives = 102/243 (41%), Gaps = 13/243 (5%)

Query: 1299 KQVREDITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            K+++ D+ V + P +F   + + +  E ++   +C +  +G  T  V+W+     I+  +
Sbjct: 5367 KELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDN 5424

Query: 1358 -RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
             ++  + E     L + +V   DS  Y C+A N +GEA+    L  +   ++       S
Sbjct: 5425 IKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL-TMGDSEIFAVIAKKS 5483

Query: 1417 GLEKIQYLED---TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTD 1473
             +     +E+    S Y  +    + V   PRF+         I G   +F+C +     
Sbjct: 5484 KVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLVR--GS 5540

Query: 1474 SNLKVEWFKNGQPVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
                V W+K+G+ V  G RF       G+  L I  L+  D G Y C A N  G  E   
Sbjct: 5541 PRPTVYWYKDGKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFA 5599

Query: 1533 RLT 1535
             LT
Sbjct: 5600 ALT 5602



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 48/201 (23%), Positives = 80/201 (39%), Gaps = 9/201 (4%)

Query: 2672 PNLKIEWFKNGVTLTT-GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P  +++W+K  + +     +   + + G  TL I ++   DS  Y C+A N +GEA+   
Sbjct: 5407 PTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRG 5466

Query: 2731 SIKIEDRHWLL----GESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCK 2786
             + + D            +   SL     L                   FI  +++    
Sbjct: 5467 FLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAP 5526

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSLDITHTYEEDSGI 2845
             G   +F+C V  S  PT  + W+ + K L  G R+      + + +L IT   + D G 
Sbjct: 5527 IGTAAYFQCLVRGSPRPT--VYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGE 5583

Query: 2846 YTCKATNSKGSATTSGSLRCT 2866
            Y C ATN  G A +  +L  T
Sbjct: 5584 YRCVATNKSGMAESFAALTLT 5604



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L ++  +R+G     + R+T    P +K  +Y +G  +++   F+   +     
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            L I+  YPEDSG Y   A N+ G A +TA + VQG+  +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 56/259 (21%), Positives = 98/259 (37%), Gaps = 12/259 (4%)

Query: 2887 VEQAEEARLAKGRRPSVPDTEYP-KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKI 2945
            V    EA++ +  R   P  E P  P  ++       ++EG+ + LE  +     P   +
Sbjct: 918  VLHGREAKVTETARVPAP-VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT--V 974

Query: 2946 EWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS 3005
             WY     +E    F++T   G   L + + +  DSG +TC A N+ G   TS  +    
Sbjct: 975  TWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 1034

Query: 3006 KDNLIERT---QHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD-IS 3061
             +   + T        TE    +++ +  +      +     G P     + K +V  + 
Sbjct: 1035 SEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLV 1094

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTTDSG 3119
            EG    +   +   G+    + W  +G  +   +R +  Y    G   L I  T   D+G
Sbjct: 1095 EGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1152

Query: 3120 TYSCRATNKWGQAEISVKL 3138
             Y+    NK G+   S  L
Sbjct: 1153 EYTIVVRNKHGETSASASL 1171



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 6/136 (4%)

Query: 1803 QSKASLQLESQHESALQKIQQLEDSS-RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQS 1861
            +SK   Q E     A+ + Q  +    R+    D+    N+ P+ + ++    +  EG S
Sbjct: 4119 ESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSDI---TNEPPKMLQEMPKHARCREGDS 4175

Query: 1862 AHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
               EC I   P P   V W+ NG +L+   +++         L I  V  +DSG+Y C A
Sbjct: 4176 IILECLISGEPQPV--VTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVA 4233

Query: 1922 INNLGQAVSSIRLNVQ 1937
             NN G   S   L V+
Sbjct: 4234 ENNSGAVESVSDLTVE 4249



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 21/205 (10%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI- 694
            PP FI PL      E   + F   +E  G P   ++W +N   +E   R   + R G + 
Sbjct: 5182 PPSFIEPLTKRKVYENTTLGFIVEVE--GLPVPGVKWYRNKSLLEPDERI-KMERVGNVC 5238

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            SL++ ++   + GEY C AV+  G A++ A + + P+         P T Q++ + +   
Sbjct: 5239 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFD--- 5295

Query: 755  KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT 814
                   +E  TS R    + +    EL E     FE Q+  V+ P    E+  D + + 
Sbjct: 5296 -------LEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVP----EFTPDHKSMI 5344

Query: 815  ASSRITSIFNFGYVSLNIMHLRAED 839
             S     +  F +V  N+     ED
Sbjct: 5345 VS---LDVLPFNFVDPNMDSREGED 5366



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 11/122 (9%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKT 2428
            +T Q P FTQPLQ++  + EG TA F+  +   G P  +V WFR+ ++I  S+   +  +
Sbjct: 1    MTTQAPTFTQPLQSV-VVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQIS 57

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ 2488
               G   +TI  V   + G Y  +A+N  G+              ++ ET  P  ++++Q
Sbjct: 58   FSDGRAKLTIPAVTKANSGRYSLKATNGSGQ------ATSTAELLVKAETAPPNFVQRLQ 111

Query: 2489 KL 2490
             +
Sbjct: 112  SM 113



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 5/98 (5%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDF 2697
            QAP FT  L+S   ++EG     EA +     P  ++ WF++G  ++T     ++ +F  
Sbjct: 4    QAPTFTQPLQSV-VVLEGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G   L+I ++   +SG Y+ KATN  G+A STA + ++
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 5/98 (5%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            EP P + +++ K+AR  +G +   E  + G P PVV+W +    L +  K+  ++ E   
Sbjct: 4156 EP-PKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKF--QFEEVNC 4212

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQP 163
               L IK +   D G+Y C A N  G  E++  + ++P
Sbjct: 4213 SHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEP 4250



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E +PP F Q  ++    QG   + + ++ G PTPVV + R  A +     + +    Q G
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQI---SQEG 156

Query: 128 DV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           D+ SLLI +  P D G Y+  A N  G A  +  +  +G
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L ++  ++G  +  +  V  +  PT  ++++ +   + S   ++ + +    SL I
Sbjct: 106  FVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               Y EDSG Y+  ATNS G AT++  L   G++ +    +  +       + ++ + R+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV--PAKKTKTIVSTAQISESRQTRI 221

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923
             K              E +I  AA  QL
Sbjct: 222  EKKIEAHFDARSIATVEMVIDGAAGQQL 249



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 5/107 (4%)

Query: 2355 ELESAEPFKRP-EIPEPVTRQRPV-FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEW 2412
            E+  ++ F  P E  EP   + P  F +PL     + E  T  F   +   G P   V+W
Sbjct: 5160 EIWRSDSFGTPNEAIEPKDNEMPPSFIEPLTK-RKVYENTTLGFIVEV--EGLPVPGVKW 5216

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +RN+ L+E   RI         S+ IS+++  + G YMC A N++GE
Sbjct: 5217 YRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGE 5263



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 1/118 (0%)

Query: 378  ETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            E +  ++ISE +A+   F    ++  + EG    F C+++G P P++ W+ + ++I+   
Sbjct: 1276 EEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE 1335

Query: 437  NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             +++   + G  +L I  V   D G+ T  A N  G      +L V     + AP ++
Sbjct: 1336 RYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1393



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 65/316 (20%), Positives = 120/316 (37%), Gaps = 20/316 (6%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PPSF    ++  V  G          G     V W  N   + P  +N I+     Y++L
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPI-PRNQNFIIHSLENYSIL 4001

Query: 4573 ILEA-YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP--EIIEPL 4629
             L + + Q+ G   CV  N  G  +       S+   K K K   KA   P   + ++  
Sbjct: 4002 TLSSVHHQNEGSITCVLFNQYGTVK-----TTSMLKVKAKQKHDVKAHKVPVFHDYLDEE 4056

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
            ++  +   QA      +  +    +   K +  + PS   ++     E  +  +   PE 
Sbjct: 4057 EELALVFDQAKGAHPSMSQEGQTNLHLLKTNPPVPPSGDTELLSFPVEIQVTAATPIPEQ 4116

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQ-----ADNLPALTP--LRDIVVY----EGQPA 4738
            + + K V            + +VTQ  +       ++    P  L+++  +    EG   
Sbjct: 4117 DKESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSI 4176

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              +  I+ + +P + W + G L+ +   FQ      +  L I +   +D+G + C A   
Sbjct: 4177 ILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENN 4236

Query: 4799 AGQVETSAKLVVKSKT 4814
            +G VE+ + L V+  T
Sbjct: 4237 SGAVESVSDLTVEPVT 4252



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 27/116 (23%), Positives = 49/116 (42%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   Q+  + ++ EG    F     G P+P VTW+ N   +  +    I +  N++ L 
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILT 4002

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
            + +    + G  T +  N  G + T+  L V++  +  V+  +     D    E E
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYLDEEEE 4058



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            +PP      KN    +G +   E  + G P+P V+W R+   +     + + +  Q+G  
Sbjct: 941  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF--QSGIA 998

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             L+I++    D G +TC+A N+ G    S Y+
Sbjct: 999  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL 1030



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 8/116 (6%)

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
            + LE+    K    I ES  ++  F  R K+   ++EG  V F CK+        K+ W+
Sbjct: 1269 ELLEEDGEEKMAVDISESEAVESGFDLRIKNYR-ILEGMGVTFHCKMSGYPLP--KIAWY 1325

Query: 1482 KNGQPVTIGHRFRPIHDF---GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            K+G+ +  G R++   DF   G  +L I  ++ ED GIYT  A N+ G    S +L
Sbjct: 1326 KDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL 1379



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 12/173 (6%)

Query: 3050 FTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLE 3109
            FT   +D+V   +  +A +E     T +  + ++W+ +G  +    + R      +  L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3110 ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHF 3169
            IL   T+D+  YSC         + +VK       +G    F   +Q+IE + +  S   
Sbjct: 2233 ILTIDTSDAEDYSCVLVE-----DENVKTTAKLIVEGAVVEFVKELQDIE-VPESYSGEL 2286

Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            EC V P    +++ +WYHN   ++ + +    S  G   L +      D GEY
Sbjct: 2287 ECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2336



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 405  EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE-SGNHALMITNVTLSDSGVV 463
            EG     +C ++G P P VTWF N   ++   N K    E + +H L I +V   DSG  
Sbjct: 4172 EGDSIILECLISGEPQPVVTWFQNGVLLKQ--NQKFQFEEVNCSHQLYIKDVNSQDSGKY 4229

Query: 464  TCVARNKSG 472
             CVA N SG
Sbjct: 4230 KCVAENNSG 4238



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI  +    V E+  + F   VE    P   ++WYRN  LL    R +        S
Sbjct: 5182 PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDERIKMERVGNVCS 5239

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L+I  +   + GEY+C AVN  GE
Sbjct: 5240 LEISNIQKGEGGEYMCHAVNIIGE 5263



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 49/204 (24%), Positives = 80/204 (39%), Gaps = 8/204 (3%)

Query: 2535 VGDPSLRFEWYINGVELKMGS-RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXX 2593
            +G P+   +WY   + ++  + ++  + + G  TL I +V  +D+  Y C+A+N  G   
Sbjct: 5404 IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAI 5463

Query: 2594 XXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAM--NKVPEMFVDTGVQQAPIFTTHLKSY 2651
                            A + +      ++E  +  N     F    V+  P F   +   
Sbjct: 5464 CRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDC 5523

Query: 2652 DKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRND 2710
               + G   Y +  V  R  P   + W+K+G  L  G R        G   L I SL   
Sbjct: 5524 YAPI-GTAAYFQCLV--RGSPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKS 5579

Query: 2711 DSGIYTCKATNLLGEAVSTASIKI 2734
            D G Y C ATN  G A S A++ +
Sbjct: 5580 DEGEYRCVATNKSGMAESFAALTL 5603



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 44/177 (24%), Positives = 74/177 (41%), Gaps = 12/177 (6%)

Query: 3346 YCYEENSGEYE---CVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKL--- 3397
            + Y E   EYE    +   K+ +D+         +E  I   + +L + +E  + K    
Sbjct: 1209 FVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLE 1268

Query: 3398 QTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWY 3457
            + LE+    +    + E +     F + + N   L EG    F  +++    P  K+ WY
Sbjct: 1269 ELLEEDGEEKMAVDISESEAVESGFDLRIKNYRIL-EGMGVTFHCKMSGYPLP--KIAWY 1325

Query: 3458 WNGKSLKAGSRFR-TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             +GK +K G R++  F   G   L I    PED G Y   A N  G A+ +  + V+
Sbjct: 1326 KDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 69   PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
            P PP   Q  +      G  A+F   + G P P +SW +++  L    K    ++ Q  +
Sbjct: 3236 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQ--E 3293

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
             +LL+ +  P D   YTC A+N YG A  S  +  E
Sbjct: 3294 YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F+ +++S TV +   VR + RV     P   +++YR+G  + S   ++   +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDL 158

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             SL I   Y EDSG Y   A N  G   + A +
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 32/89 (35%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH-DFSYVSLD 2834
            F   + N    EG  + F C +  S  P  KI W+ + K +  G RY+         SL 
Sbjct: 1293 FDLRIKNYRILEGMGVTFHCKM--SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLR 1350

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I     ED GIYT  A+N KG+A  SG L
Sbjct: 1351 IPVVLPEDEGIYTAFASNIKGNAICSGKL 1379



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 68/276 (24%), Positives = 108/276 (39%), Gaps = 37/276 (13%)

Query: 2904 PDTEYPK-PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            PD E P  P  II    +    EGQ    + +V   +  DLK+ WY   K ++    F++
Sbjct: 3336 PDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRM 3392

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLI-ERTQHPKGTEG 3021
            T       L++ + Y  D G YT  A N  G+  +++ +   + ++++ ER +     E 
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEM 3452

Query: 3022 LE-----KIQNLEDSLRKEPGQQPDDD---------------TGRPPE-FTTVFKDIVD- 3059
             E     + ++ E   R       D D               T   PE F   F   +  
Sbjct: 3453 KELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTF 3512

Query: 3060 --ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV-----VLEILG 3112
              + EG+   +   LI      M   WF+N + I    R R + A   +      LEI  
Sbjct: 3513 KYVLEGEPVVFTCRLIACPTPEMT--WFHNNRPIPTGLR-RIIKAESDLHHHSSSLEIKR 3569

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK 3148
             +  DSG+Y   A N  G AE +  L  + K + +K
Sbjct: 3570 VQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEK 3605



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY---- 4678
            P   + L  K V EG+ + F+C+++  P P + W+  ++ I       +   +D +    
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            +L I      D G Y+ +A NS G     A L V Q  Q
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQ 3602



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 12/139 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-- 2164
            Q P F   L S+  L EG  A FE  +     P   + WF +GQ I           F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSD 60

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
            G   L I      +SG Y  KATN  G+A +T  L V        +T  PN +++++ + 
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------ETAPPNFVQRLQSMT 114

Query: 2225 A-QGHSTRIEVEEPKISPP 2242
              QG   R++V    I  P
Sbjct: 115  VRQGSQVRLQVRVTGIPTP 133



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 4/130 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P F   ++ + V +      + R+   G P   V++ R+G  I++S       +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L +    PEDSGTY+  A N +G A +++ L VQ +   ++ ++    +    Q+ +S
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--EVPAKKTKTIVSTAQISES 216

Query: 1828 SRYQRREDVE 1837
             + +  + +E
Sbjct: 217  RQTRIEKKIE 226



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 4/134 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+  L+S+T  +G ++  + R+   G PT  +++ ++G  I++S  F         S
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
           L +     +DSG Y+  A ++ G A + A L V  +   E  ++  +T+    Q+ +  +
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV--QGEEEVPAKKTKTIVSTAQISESRQ 218

Query: 756 YQHQESIEEQTSQR 769
            + ++ IE     R
Sbjct: 219 TRIEKKIEAHFDAR 232



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYVAL 1770
            F + +K+ R+ E     F  ++   G P  ++ W ++G  I+   R  +  + D G  +L
Sbjct: 1293 FDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQD-GRASL 1349

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
             +  V PED G YT  A N  G A+ S  L+V+  A L
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPL 1387



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 7/136 (5%)

Query: 3658 EPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDC 3717
            E QL +  +      ++ EE +   E    +  +  PP F  EI+   +V EG   +F C
Sbjct: 3907 ELQLSASTRIDEFKTEQKEENMRFFENSFRKRPQRCPPSFLQEIESQ-EVYEGDSCNFVC 3965

Query: 3718 RVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGFIALDIDYIYARDAGEYTCRATNK 3775
              +  G P   + W++N  P        +H+L ++  + L    ++ ++ G  TC   N+
Sbjct: 3966 HFQ--GYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTLSS--VHHQNEGSITCVLFNQ 4021

Query: 3776 WGSATTTAKITCSAKR 3791
            +G+  TT+ +   AK+
Sbjct: 4022 YGTVKTTSMLKVKAKQ 4037



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 4/112 (3%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            E IE  +  + P F++    R V E     F   V G P P V W+ N   +  D   +I
Sbjct: 5172 EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPD--ERI 5229

Query: 441  LVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI-EKEQVVA 490
             +   GN  +L I+N+   + G   C A N  GE      ++++ ++E+VVA
Sbjct: 5230 KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVA 5281



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 2/107 (1%)

Query: 1834 EDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
            E +E   N+ P    +     K+ E  +  +   +E  P P   V+WY N  +L+   R 
Sbjct: 5172 EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDERI 5229

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            +        +L+I  +   + GEY C A+N +G+A S   +++  +E
Sbjct: 5230 KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQE 5276



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS--RFTSIFRFGYI 694
           P F  PL+SV  +EG    FE  I   G P  ++ W ++GQ I  S+       F  G  
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + ++   +SG Y+ +A + +G A + A L V
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 47/195 (24%), Positives = 74/195 (37%), Gaps = 7/195 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKN-RFTPIYDF 4028
            + PPRF+  I     + E     F+C +  +G P  +V+W+     +   N ++    + 
Sbjct: 5377 EMPPRFIMPI-CDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEK 5433

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIR 4088
            G   +    V   DS  Y CRA N  G    +  + T G   I +     K   ++  + 
Sbjct: 5434 GSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL-TMGDSEI-FAVIAKKSKVTLSSLM 5491

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            E         +   E      PP F+          G  A F C V G P+P V W  +G
Sbjct: 5492 EELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDG 5551

Query: 4149 NTIVNGSRYKLTYDG 4163
              +V G R+ +   G
Sbjct: 5552 K-LVQGRRFTVEESG 5565



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 48/197 (24%), Positives = 78/197 (39%), Gaps = 11/197 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGS-RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P  +++WY     +E  + ++ ++ + G  TL + +V   DS  Y C+A N  GEA    
Sbjct: 5407 PTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRG 5466

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDD---TGRPPEFTTVFKD 3056
              + T  D+ I      K    L  +  +E+ + K        +      PP F     D
Sbjct: 5467 --FLTMGDSEIFAVIAKKSKVTLSSL--MEELVLKSNYTDSFFEFQVVEGPPRFIKGISD 5522

Query: 3057 IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTT 3116
                  G  A+++   +  G     + W+ +GK ++           G   L I     +
Sbjct: 5523 CY-APIGTAAYFQC--LVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKS 5579

Query: 3117 DSGTYSCRATNKWGQAE 3133
            D G Y C ATNK G AE
Sbjct: 5580 DEGEYRCVATNKSGMAE 5596



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 4/93 (4%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-DFGLVTL 2702
            F   +K+Y +++EG  V    ++     P  KI W+K+G  +  G R +  F   G  +L
Sbjct: 1293 FDLRIKNY-RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASL 1349

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             I  +  +D GIYT  A+N+ G A+ +  + +E
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 16/156 (10%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMS 1641
            +KN  I EG    F  ++   S   L K+ WY + K +K G R+  +    G  +L I  
Sbjct: 1297 IKNYRILEGMGVTFHCKM---SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1353

Query: 1642 CLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE-SQHEGALPRLNQLEDTSKYQRH 1700
             LPED G YT  A N  G A+ SG         +Y+E +   GA   +  LE  S+ +  
Sbjct: 1354 VLPEDEGIYTAFASNIKGNAICSG--------KLYVEPAAPLGAPTYIPTLEPVSRIR-- 1403

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
            S     ++++P+   P +      + A    AR+ P
Sbjct: 1404 SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSP 1439



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 62/230 (26%), Positives = 94/230 (40%), Gaps = 17/230 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN-RIQTYHDFGYV 1101
            PRF+ P+    KI E   A F+  V      T  V+WY     I   N +     + G  
Sbjct: 5380 PRFIMPICDF-KIPENSDAVFKCSVIGIP--TPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEE-- 1159
             L I +V   DS  Y   A N  GEA     +T+   S I      +     +  +EE  
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGD-SEIFAVIAKKSKVTLSSLMEELV 5495

Query: 1160 --SKFVEPMYQIEEISKSKPVFVQPLSNP-PPVSEGKNIHLECRLEPMGDPTMRVEWFHN 1216
              S + +  ++ + + +  P F++ +S+   P+  G   + +C +   G P   V W+ +
Sbjct: 5496 LKSNYTDSFFEFQVV-EGPPRFIKGISDCYAPI--GTAAYFQCLVR--GSPRPTVYWYKD 5550

Query: 1217 GRSVTVGSRFKTYYD-FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
            G+ V  G RF       GF  L I     +D GEY   A N  G A + A
Sbjct: 5551 GKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFA 5599



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +   +     G  A F+  +RG+P P V W  K   LV+  ++++     TG  +
Sbjct: 5513 PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWY-KDGKLVQGRRFTVE-ESGTGFHN 5570

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEA 155
            L I  +   DEGEY C A N+ G A
Sbjct: 5571 LFITSLVKSDEGEYRCVATNKSGMA 5595



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 3430 ENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPE 3488
            + + +G +AHF  R+    DP  + EWY NG  ++   R   +     V  L I     E
Sbjct: 2087 QTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2144

Query: 3489 DSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            DS   + +A N  GE  + A + VQ K+ I    +L   +    D +A  E
Sbjct: 2145 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFE 2195



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHD 1097
            TQ P F  PL+    ++EG +A FEA +         V W+ +G+ I+++    +Q    
Sbjct: 3    TQAPTFTQPLQSV-VVLEGSTATFEAHISGFP--VPEVSWFRDGQVISTSTLPGVQISFS 59

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             G   L I +V   +SG Y++ A N +G+A  +A + V+  ++
Sbjct: 60   DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 11/139 (7%)

Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            +IE+  P +  P+    ++  T V +G  AHF  +V  V  P+   E+Y NG  ++ + R
Sbjct: 2068 KIELS-PSMEAPKIFERIQSQT-VGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDR 2123

Query: 2291 FHITFDFGYV-SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG 2349
             +  +    V  L I+    ED+    VKAIN  G  +S   + V AK  I    +  + 
Sbjct: 2124 IYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDV 2183

Query: 2350 LEKIR------ELESAEPF 2362
            + K +      E E++EPF
Sbjct: 2184 VAKEKDTMATFECETSEPF 2202



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            V   KI +KP++    E A   F+V +S +  P V WF     +  S+KH +++      
Sbjct: 2792 VETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHK 2850

Query: 323  LRVRNTQKSDSGHYT 337
            L ++N   SD+G YT
Sbjct: 2851 LMLQNISPSDAGEYT 2865



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 8/109 (7%)

Query: 3809 KELERGRISDAPKEE-----PIVSTPPKFITQIKSHT-VEESEGVRFECRVEPKEDPKLR 3862
            K + + +++ +PK        I + PPK + ++  H    E + +  EC +  +  P   
Sbjct: 4132 KAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPV-- 4189

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            + W++NG LL    +++         L I  V ++DSG+Y C A N+ G
Sbjct: 4190 VTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSG 4238



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/108 (22%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +++ +  T  P     L+++ +++G +   + R+  +   T  V++Y +   ++S   F 
Sbjct: 94   ELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQ 151

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             +      +L I    PEDSGTY+  A N++G A ++   +V  ++ +
Sbjct: 152  ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 8/127 (6%)

Query: 619  ERARPYIPPGEEDRVYPPPQFIVP-----LKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            E  +  IP  + D++   P    P     ++S T  +G   HF  R+  VG P  + EW 
Sbjct: 2055 EEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRV--VGKPDPECEWY 2112

Query: 674  KNGQSIEASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            KNG  IE S R    +       L +  +  +DS     +A++  G   + A L V  + 
Sbjct: 2113 KNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172

Query: 733  TIERTSQ 739
             I  T +
Sbjct: 2173 LITFTQE 2179



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 10/131 (7%)

Query: 636  PPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            PP+ +  + K     EG  I  E  I   G+P   + W +NG  ++ + +F         
Sbjct: 4157 PPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSH 4214

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
             L +  +N QDSG+Y C A + +G  E+ + L V P  T    SQ  E +      E Y 
Sbjct: 4215 QLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEP-VTYRENSQF-ENIG-----EIYG 4267

Query: 755  KYQHQESIEEQ 765
            KY   + +++Q
Sbjct: 4268 KYSRDQQLQDQ 4278



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGY 2299
            P F   L+    V EG TA FE  +     P   + ++ +G+ + ++      I+F  G 
Sbjct: 6    PTFTQPLQSVV-VLEGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L I      ++G YS+KA N  G  TS   + V A+ +  +  QR + +   +  +  
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 2360 EPFKRPEIPEPVTR 2373
               +   IP PV +
Sbjct: 123  LQVRVTGIPTPVVK 136



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 1/115 (0%)

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            ++++   P  V     + V EGE      R  G P P++ W  +G  I  +   R+  DG
Sbjct: 1834 DQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1893

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRP 598
                LDI   K+ D    + TA+N  G    + +L            +R   PRP
Sbjct: 1894 -IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRP 1947



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 18/168 (10%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            KD+  +    +A +E S+      ++ ++WF+    I+ S + R V    +  L +    
Sbjct: 2802 KDVTALENATVA-FEVSV---SHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 2857

Query: 3115 TTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174
             +D+G Y+       GQ      LEC  K   +    T  ++NIE + + ++A FEC V 
Sbjct: 2858 PSDAGEYTAVV----GQ------LECKAKLFVETLHITKTMKNIE-VPETKTASFECEVS 2906

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
              + P M   W  NG  +  S + K V       L I  T   DS EY
Sbjct: 2907 HFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEY 2951



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 44/181 (24%), Positives = 81/181 (44%), Gaps = 18/181 (9%)

Query: 2067 VKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTS-----LENL 2121
            ++V A + +     + + + + +ELE    P+    + P  R VFL+ +T+     L+ +
Sbjct: 4105 IQVTAATPIPEQDKESKEVFQTEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEM 4164

Query: 2122 ------KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
                  +EGD    EC +    +P   + WF NG  ++   +++         L I    
Sbjct: 4165 PKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVN 4222

Query: 2176 AEDSGTYMCKATNKLG--EAVNTCTLKVAGHR-NIILDT--QHPNGLEKIRQLEAQGHST 2230
            ++DSG Y C A N  G  E+V+  T++   +R N   +   +      + +QL+ QG S 
Sbjct: 4223 SQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQFENIGEIYGKYSRDQQLQDQGESV 4282

Query: 2231 R 2231
            R
Sbjct: 4283 R 4283



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDF--G 3613
            P FT     +++ E S+A FE  +   PV +    V WF +G+ + T +       F  G
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQISFSDG 61

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
               L I  V + ++G Y+ KATN  G+AT + +L VK
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVS 130
            P+F +  KN    +G   + + +  GNP P + W  K + ++  +KY  +R     G+ +
Sbjct: 1556 PMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWL-KNSDIIVPHKYPKIRIEGTKGEAA 1614

Query: 131  LLIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPE 164
            L I      D   YT TA N+ G     C V ++ E
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 20/69 (28%), Positives = 36/69 (52%)

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
            REG+ ++L     G P P +TW ++GV +  N + +      +  L I    + D+  Y+
Sbjct: 4171 REGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYK 4230

Query: 563  CTAQNVAGS 571
            C A+N +G+
Sbjct: 4231 CVAENNSGA 4239



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-- 3475
            +AP FT PL ++  L EG  A FEA ++    P  +V W+ +G+ +   +       F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            G   L I      +SG Y  +A N  G+A +TA + V+ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GF 3752
            P FT  ++ ++ V EG    F+  +   G P   + WF +G+  +T +       F  G 
Sbjct: 6    PTFTQPLQ-SVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L I  +   ++G Y+ +ATN  G AT+TA++   A+
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 3/153 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T E +V+   A  PP FV    ++TV +G   R   RVTG P P V +  +G  I +   
Sbjct: 92   TAELLVKAETA--PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 4157 YKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
            ++++ +G +Y   I +    D+G   V              L V    +      K    
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVID 4248
                  ++  R E ++E  F+ R +   + VID
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVID 242



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F+ ++Q +T + +G     + R+  +  P +K  ++ +G ++     ++   +  + 
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLY 159

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             L I   Y E+SG Y   ATN +GR ++ A L    +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F     + +  +G  A+F+ K+ G P P   W      +V    + +   E  G  SL
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED-GTQSL 1515

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            +I    P D GE+T  A+N+ G +  SV +  E
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1548



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 87/362 (24%), Positives = 150/362 (41%), Gaps = 45/362 (12%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            +P  + +  S + V EG  V  E K   V+  +++  W K+GQ V    R   + D    
Sbjct: 2354 RPIAILQGLSDQKVCEGDIVQLEVK---VSLESVEGVWMKDGQEVQPSDRVHIVIDKQSH 2410

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L I D+  ED+G Y+   +  +G    S R++  S  D++        L+ + V+E   
Sbjct: 2411 MLLIEDMTKEDAGNYSF-TIPALGLS-TSGRVSVYSV-DVITP------LKDVNVIEG-- 2459

Query: 1563 KYHRTDMVDEVTTQAPICTTS---LKNVEIKEGQRAHFERRLIPVSDATLKVEWYH--NN 1617
                T  V E     P  T+    L + +IK   R    + ++  +   L +   H  + 
Sbjct: 2460 ----TKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVINRTHASDE 2512

Query: 1618 KPLKSGSRFTETN-NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS----- 1671
             P K      ETN N     + I+  L + + T T   +  + E   SGI ++ +     
Sbjct: 2513 GPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV-ELSHSGIDVLWNFKDKE 2571

Query: 1672 -KKSIYLESQHEGALPRLNQL----EDTSKYQRHSAQD----EVITQAPVFTMPMKDIRV 1722
             K S   + +  G + +L  L    +D  KY  ++ ++    ++       + P+ D  V
Sbjct: 2572 IKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVAGGAISKPLTDQTV 2631

Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782
            AE+Q A FE     V +P  + EWLR+G  +  +N + +  D     L +     +D G 
Sbjct: 2632 AESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2688

Query: 1783 YT 1784
            YT
Sbjct: 2689 YT 2690



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F   ++ ++ V +G  V    RV   G PT  + ++ +G    +        +    
Sbjct: 103  PPNFVQRLQ-SMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            +L I   Y  D+G Y+  ATN  G AT+TA++    + ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FVQ L +   V +G  + L+ R+   G PT  V+++ +G  +     F+   +    +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I  A   D+G Y+V A N +G A TS    +++  + V   + +  +   Q+ E    
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRA-TSTAELLVQGEEEVPAKKTKTIVSTAQISESRQT 219

Query: 1297 RTKQ 1300
            R ++
Sbjct: 220  RIEK 223



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 20/94 (21%), Positives = 40/94 (42%)

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            K+  + P F+E  +   V E   +       G P P + W ++   + P+  +++   G 
Sbjct: 5177 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 5236

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +L+I   +  +   Y C A N+ G   + A +
Sbjct: 5237 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 5270



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGYVALDIASVRAED 1112
            +I+EG    F  ++         + WY +GK+I    R Q  +   G  +L I  V  ED
Sbjct: 1301 RILEGMGVTFHCKMSGYP--LPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358

Query: 1113 SGVYTVVARNAAGEAQLSASMTVE 1136
             G+YT  A N  G A  S  + VE
Sbjct: 1359 EGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF-NFGYVSLNIMHLRAEDAGS 842
            EG    F  +++    P  ++ WYKDG+ I    R    F   G  SL I  +  ED G 
Sbjct: 1304 EGMGVTFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361

Query: 843  YTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
            YT  A N  G AI +  + V   + + A   IP
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP 1394



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 3/87 (3%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V   Q   F  +L       +   A +EC      +P ++V+WY +G  +  G +YR  +
Sbjct: 2168 VQAKQLITFTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHS 2224

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINN 1924
            D     L ILT+   D+ +Y+C  + +
Sbjct: 2225 DRKVHFLSILTIDTSDAEDYSCVLVED 2251



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 42/185 (22%), Positives = 74/185 (40%), Gaps = 8/185 (4%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY---- 4569
            PSFT       V  G+ V    ++      ++ W  N + +   +R  I  E   +    
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            +L I     +DSG Y  +AINS G A   A  +V      +K     K A    E +E L
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAERTHENVEAL 3623

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
             ++   E + I+   +  G P    Q  +   +++ + +F+   +A +      E + E 
Sbjct: 3624 VER--GEDR-IKVDLRFTGSPFNKKQDVEQKGMMR-TIHFKTMSSAKKTDYMYDEEYLES 3679

Query: 4690 EGDYK 4694
            + D +
Sbjct: 3680 KSDIR 3684



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 4/127 (3%)

Query: 2609 QAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEP 2668
            + + P++  Q Q+ ++  ++   +F+     + P     +  + +  EG  + LE  +  
Sbjct: 4127 EELEPKAMPQDQVTQSPKHRF--VFLSDITNEPPKMLQEMPKHARCREGDSIILECLISG 4184

Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
               P   + WF+NGV L    + +         L I  + + DSG Y C A N  G   S
Sbjct: 4185 EPQP--VVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVES 4242

Query: 2729 TASIKIE 2735
             + + +E
Sbjct: 4243 VSDLTVE 4249



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 16/115 (13%)

Query: 4080 HMKSIEK--IREMEASW-QVTPEQVVEESKARCPPVFVSLPDAVT-----------VEEG 4125
            H+ S E+  I+E+E    + T E+++EE       V +S  +AV            + EG
Sbjct: 1246 HISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEG 1305

Query: 4126 EWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYDTG 4178
                F C+++G+P P++ W  +G  I +G RY++ +  DG     IP     D G
Sbjct: 1306 MGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1360



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 639  FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF-RFGYISLD 697
            F + +K+   +EG  + F  ++   G P  KI W K+G+ I+   R+   F + G  SL 
Sbjct: 1293 FDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLR 1350

Query: 698  MLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            +  +  +D G YT  A +  G A     L+V P A +   +  P TL+ + ++   S
Sbjct: 1351 IPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP-TLEPVSRIRSLS 1406



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLR--GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            P F++   + R  + G A FE +L   G+PT VV W     PL   N+  +R   + G  
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR--LRMINEFGYC 1760

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL        D G  TC A N+YG
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYG 1784



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/128 (22%), Positives = 52/128 (40%), Gaps = 3/128 (2%)

Query: 3251 SLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVD 3310
            S + D     ++ E+++  +      P   PP F+ +I+   ++ EG S +F        
Sbjct: 3913 STRIDEFKTEQKEENMRFFENSFRKRPQRCPPSFLQEIES-QEVYEGDSCNFVCHFQGYP 3971

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
             P   V W+ N   +P    +         IL +   + +N G   CV  N+ G   T +
Sbjct: 3972 QPI--VTWYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTS 4029

Query: 3371 NLKCTSKE 3378
             LK  +K+
Sbjct: 4030 MLKVKAKQ 4037



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 44/168 (26%), Positives = 72/168 (42%), Gaps = 10/168 (5%)

Query: 1671 SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPM-KDIRVAENQAAH 1729
            SK+    E     A+P+ +Q+  + K+ R     ++  + P     M K  R  E  +  
Sbjct: 4120 SKEVFQTEELEPKAMPQ-DQVTQSPKH-RFVFLSDITNEPPKMLQEMPKHARCREGDSII 4177

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
             E  +   G+P+  V W +NGV ++ + +           L +K VN +DSG Y C A N
Sbjct: 4178 LECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAEN 4235

Query: 1790 ELGEAVTSSTLFVQS---KASLQLESQHE--SALQKIQQLEDSSRYQR 1832
              G   + S L V+    + + Q E+  E      + QQL+D     R
Sbjct: 4236 NSGAVESVSDLTVEPVTYRENSQFENIGEIYGKYSRDQQLQDQGESVR 4283



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 2/82 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+ E   +    +VE    P +K  W++N   L    R+K      + +L I++++  + 
Sbjct: 5193 KVYENTTLGFIVEVEGLPVPGVK--WYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEG 5250

Query: 2713 GIYTCKATNLLGEAVSTASIKI 2734
            G Y C A N++GEA S A++ I
Sbjct: 5251 GEYMCHAVNIIGEAKSFANVDI 5272



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033
            + P F +P+++  V EG     EA ++    P   V W+ +G+ +        + ++  G
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
               L I      ++G Y  KATN  G+A +T+ + V A++
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFD 1366
            QAP F++ L ++  +EG+    E  +   G     V WF +G+ I T      + ++   
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
               L + +V   +SG Y+ +ATN  G+A ++  L V A+
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/97 (32%), Positives = 48/97 (49%), Gaps = 7/97 (7%)

Query: 2944 KIEWYFNGKVLEQGSRFKLTSDF---GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            KI WY +GK ++ G R+++  DF   G  +L +  V   D GIYT  A N +G A  S  
Sbjct: 1321 KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGK 1378

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLED-SLRKEP 3036
            +Y      L   T  P   E + +I++L   S+ + P
Sbjct: 1379 LYVEPAAPLGAPTYIPT-LEPVSRIRSLSPRSVSRSP 1414



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 37/118 (31%), Positives = 50/118 (42%), Gaps = 5/118 (4%)

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            +P  IE     + P     + S + + +G  AHF  RV    DP    +W+ NG KI   
Sbjct: 2065 KPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERS 2121

Query: 2156 HR-YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQ 2212
             R Y    +     L I    AEDS + M KA N  GE  +   L V   + +I  TQ
Sbjct: 2122 DRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA-KQLITFTQ 2178



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 42/175 (24%), Positives = 69/175 (39%), Gaps = 13/175 (7%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            + +K  +D    E     F+  V+    P V WF  + +I+    H+ LV+E   H LM+
Sbjct: 2796 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLML 2853

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             N++ SD+G  T V     G+   +C+  +     V      +    + V E +      
Sbjct: 2854 QNISPSDAGEYTAVV----GQ--LECKAKLF----VETLHITKTMKNIEVPETKTASFEC 2903

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
                   P + W K+GV I  + + +I   G    L I      D+A Y     N
Sbjct: 2904 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2957



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/119 (23%), Positives = 50/119 (42%), Gaps = 2/119 (1%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +  Q E+  ++  +S +       P F   ++   V E  + +F       G P+  V W
Sbjct: 3920 KTEQKEENMRFFENSFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHF--QGYPQPIVTW 3977

Query: 1747 LRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
              N +PI  +          Y  L +  V+ ++ G+ TC   N+ G   T+S L V++K
Sbjct: 3978 YNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAK 4036



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/132 (21%), Positives = 58/132 (43%), Gaps = 8/132 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  + +    EGD+ +F C+ +    P   + W+ N+ P+P    +      +Y  L +
Sbjct: 3946 FLQEIESQEVYEGDSCNFVCHFQGYPQPI--VTWYNNDMPIPRNQNFIIHSLENYSILTL 4003

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
            +  + ++ G  TC   N  G+  T+  L+    +    D +  +     + +++ EE  L
Sbjct: 4004 SSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQK--HDVKAHKVPVFHDYLDEEEELAL 4061

Query: 2896 ----AKGRRPSV 2903
                AKG  PS+
Sbjct: 4062 VFDQAKGAHPSM 4073



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 33/116 (28%), Positives = 46/116 (39%), Gaps = 2/116 (1%)

Query: 2475 QLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVP 2534
            Q E   P+ M + Q  + P  R     D   E P   Q +   +   EG     E  +  
Sbjct: 4125 QTEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLIS- 4183

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             G+P     W+ NGV LK   +F+         L I  V + D+G Y C A N +G
Sbjct: 4184 -GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSG 4238



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 2785 CKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSG 2844
            C+EGD+I  EC +  S +P   + WF N   L    +++         L I     +DSG
Sbjct: 4170 CREGDSIILECLI--SGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSG 4227

Query: 2845 IYTCKATNSKGSATTSGSL 2863
             Y C A N+ G+  +   L
Sbjct: 4228 KYKCVAENNSGAVESVSDL 4246



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/84 (27%), Positives = 35/84 (41%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F Q  ++    +G  A FE  + G P P VSW R    +       ++ +   G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155
            I  +   + G Y+  A N  G+A
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA 89



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            T  P F+  L+    + +G     + RV      T  V++Y +G +I S+   Q   +  
Sbjct: 101  TAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQISQEGD 157

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
              +L IA    EDSG Y+V A N+ G A  +A + V+    +
Sbjct: 158  LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 1/82 (1%)

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
            V EG+ A+F+ ++T   +P + W   G LI ++  F++ ++G +  L I +    DTG  
Sbjct: 1852 VLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIH-YLDIVDCKSYDTGEV 1910

Query: 4792 TCRATTAAGQVETSAKLVVKSK 4813
               A    G +E   KL ++ +
Sbjct: 1911 KVTAENPEGVIEHKVKLEIQQR 1932



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 4/99 (4%)

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            FK  +I    + + P   + +Q+   + +G  AHF  R+  VG P  + EW++N   IE 
Sbjct: 2064 FKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIER 2120

Query: 2422 SSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S RI     +     + I  V  ED    M +A N+ GE
Sbjct: 2121 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE 2159



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 3284 FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343
            F  ++QDV    +   A FE       +P +KV+W+ +G ++  G +YR   D  +  L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3344 ILYCYEENSGEYECV 3358
            IL     ++ +Y CV
Sbjct: 2233 ILTIDTSDAEDYSCV 2247



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 10/96 (10%)

Query: 771  QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS- 829
            +F + ++D+  L++ R A FE +   VS+P + V+W KD + +  + RI  I    YV  
Sbjct: 3059 EFRKHIKDIKVLEKKR-AMFECE---VSEPDITVQWMKDDQELQITDRI-KIQKEKYVHR 3113

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            L I   R  DAG YTV A    G  +STA + V  R
Sbjct: 3114 LLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3145



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/121 (23%), Positives = 51/121 (42%), Gaps = 3/121 (2%)

Query: 3396 KLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVE 3455
            K +  E++M R  + S  +   + P   +     + + EG++ +F         P   V 
Sbjct: 3920 KTEQKEENM-RFFENSFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPI--VT 3976

Query: 3456 WYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            WY N   +     F       + IL +S  + ++ G   C  +N YG   TT+ +KV+ K
Sbjct: 3977 WYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAK 4036

Query: 3516 R 3516
            +
Sbjct: 4037 Q 4037



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 10/133 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP FV ++QS T     + ++   Q+   G P   V+++ +G  +     F    +    
Sbjct: 103  PPNFVQRLQSMTV---RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP-KHMKSIEKIREM 4090
            ++     YPEDSG Y   ATN  G   + A +   G      + ++P K  K+I    ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EEEVPAKKTKTIVSTAQI 213

Query: 4091 EASWQVTPEQVVE 4103
              S Q   E+ +E
Sbjct: 214  SESRQTRIEKKIE 226



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            +E P+  + I++  V +G   H    +    DP    EWY NG  +++  R    +    
Sbjct: 2075 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDN 2132

Query: 2035 VA-LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            V  L I    AED+ + M KA N  GE  + + + V AK
Sbjct: 2133 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 49/206 (23%), Positives = 89/206 (43%), Gaps = 19/206 (9%)

Query: 4352 ESTVHGKEVHVAKQKQTQKEVVGDKEITRKITS---TETTEIEHKAQTQERVVEGPVKPS 4408
            ES +H +     + +  +    G+ E + + T    +++ +I+HK+   +R        S
Sbjct: 3437 ESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTS 3496

Query: 4409 K-----PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN------SPDF 4457
                   P FT+K+    V E E   F       P P + W+  N PI          + 
Sbjct: 3497 SWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAES 3556

Query: 4458 QIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT 4517
             +H  S  S L I++V   DS  +  +A N  G+A+ +A+L+V +K +  +         
Sbjct: 3557 DLHHHS--SSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAE 3614

Query: 4518 LTAQNVN--VTSGQ-LVRLDTKVTGT 4540
             T +NV   V  G+  +++D + TG+
Sbjct: 3615 RTHENVEALVERGEDRIKVDLRFTGS 3640



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F Q  ++    +G +  F    +G P P+V+W     P+     + +   E      
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYS--I 4000

Query: 131  LLIKQIGPGDEGEYTCTARNQYG 153
            L +  +   +EG  TC   NQYG
Sbjct: 4001 LTLSSVHHQNEGSITCVLFNQYG 4023



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 4/97 (4%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            D E P P +I P+  + ++ E   L    +VE    P +K  WY N  +LE   R K+  
Sbjct: 5178 DNEMP-PSFIEPLT-KRKVYENTTLGFIVEVEGLPVPGVK--WYRNKSLLEPDERIKMER 5233

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
                 +L++ ++ + + G Y C A N  GEA + + V
Sbjct: 5234 VGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 5270



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +TTQAP  T  L++V + EG  A FE  +   PV +    V W+ + + + + +      
Sbjct: 1    MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQI 56

Query: 1631 NF--GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            +F  G   L I +    +SG Y+ +A N  G+A ++   +V ++
Sbjct: 57   SFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 46/180 (25%), Positives = 69/180 (38%), Gaps = 16/180 (8%)

Query: 396  KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
            K  ++ +V E K   F+C V+    P + W  N  +I      KI+V +   H L+I N 
Sbjct: 2886 KTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVV-QGKLHQLIIMNT 2943

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARA 514
            +  DS            E  F C  + +     V P  +      +N  E + +      
Sbjct: 2944 STEDSA-----------EYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEV-T 2991

Query: 515  VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            V        W K+GV I    + ++ T     +L+I      DAA Y   A   A STAT
Sbjct: 2992 VNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA-GKATSTAT 3050



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSL 2833
            F   L ++V  EG    FE ++  S  P  ++ WF + + + + T       FS     L
Sbjct: 8    FTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I    + +SG Y+ KATN  G AT++  L
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 3/91 (3%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS-NDFGFAALDILTVYGED 1913
            K  EGQ+A ++ ++   P P     W+ +G+ + + + ++    + G  +L I+     D
Sbjct: 1467 KCLEGQTARFDLKVVGRPMPE--TFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSD 1524

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            SGE+T  A N  G++  S+ L V++ E  ++
Sbjct: 1525 SGEWTVVAQNRAGRSSISVILTVEAVEHQVK 1555



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 15/157 (9%)

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA 4723
            K   Y ++ R   +  L  ++   E+E   K +A    G++T+       +PD+ +  P+
Sbjct: 2023 KDESYEELLRKTKDELLHWTKELTEEEK--KALA--EEGKITIPT----FKPDKIELSPS 2074

Query: 4724 LTP------LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNA 4776
            +        ++   V +G  A F+ ++  K  P  +W + G  I  +        E N  
Sbjct: 2075 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVC 2134

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             L+I +   ED+ +   +A   AG+  + A L+V++K
Sbjct: 2135 ELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 2244 FVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLD 2303
            FV EL+    V E  +   EC V P    N+  ++YHN   L+S  ++ IT   G  +L 
Sbjct: 2269 FVKELQDI-EVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 2304 IQHCVPEDAGEYS 2316
            ++    ED GEYS
Sbjct: 2325 VKDVTKEDQGEYS 2337



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
            L+++E+ E      E     VS   ++ +WYHN+  LKS  ++T T+  G   L +    
Sbjct: 2273 LQDIEVPESYSGELE---CIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVT 2329

Query: 1644 PEDSGTYT 1651
             ED G Y+
Sbjct: 2330 KEDQGEYS 2337



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 64/331 (19%), Positives = 127/331 (38%), Gaps = 35/331 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            K+    +     FE  +  +  PV  W  K   +   +K+ +    +     L+++ I P
Sbjct: 2802 KDVTALENATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVSERKVH--KLMLQNISP 2858

Query: 139  GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
             D GEYT       G+  C   +  E                   + +E     T  +  
Sbjct: 2859 SDAGEYTAVV----GQLECKAKLFVE-----------TLHITKTMKNIEVPETKTASFEC 2903

Query: 199  EQSR-QTQKVAYTNGTDHSSTDDFKV---DTFEYRLLREVSFRESITKRYVGESDVQIST 254
            E S      +   NG +   ++ FK+         ++   S  +S    +V  +D Q+S 
Sbjct: 2904 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND-QVSA 2962

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
             +      V+P  I    ++   +E     F+V ++        W KNG  + +++K ++
Sbjct: 2963 TLT-----VTPIMITSMLKDINAEEKDTITFEVTVNYEGIS-YKWLKNGVEIKSTDKCQM 3016

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
             T     +L +RN    D+  YT +A    G   ++  L VE+    + +  +   + + 
Sbjct: 3017 RTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHIKDIKVLEK 3072

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTE 405
            ++   E   E+SE  +  Q++K  Q+  +T+
Sbjct: 3073 KRAMFE--CEVSEPDITVQWMKDDQELQITD 3101



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            +K++   E     FE  +     P+M   WLKNG  IE S +F  + +     L +++ +
Sbjct: 2888 MKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2944

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTP 730
             +DS EYT       G  +  A L VTP
Sbjct: 2945 TEDSAEYT----FVCGNDQVSATLTVTP 2968



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 760  ESIEEQTSQRP-QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
            E+IE + ++ P  FI PL    ++ E     F  ++  +  P   V+WY++   +    R
Sbjct: 5172 EAIEPKDNEMPPSFIEPLTKR-KVYENTTLGFIVEVEGL--PVPGVKWYRNKSLLEPDER 5228

Query: 819  ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQR 878
            I         SL I +++  + G Y   AVN +GEA S A++ +  +      L  P   
Sbjct: 5229 IKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTH 5288

Query: 879  RYI 881
            +++
Sbjct: 5289 QHV 5291



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 10/120 (8%)

Query: 3943 LTQMEATIKKYTSEVYLTEDD----LYDVDKKQPPR--FVTQIQSQTSLVEMETTKFECQ 3996
            + ++E  I K T E  L ED       D+ + +     F  +I++   L  M  T F C+
Sbjct: 1255 IKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVT-FHCK 1313

Query: 3997 LAPVGDPNMKVEWFFNGKPLLHKNRF-TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            ++  G P  K+ W+ +GK + H  R+       G  ++    V PED G Y   A+N+ G
Sbjct: 1314 MS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1371



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 8/126 (6%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            FT  L ++    +   A FE     T +P +KV+WY +G  +  G ++R   D     L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK-RNIILESQ---LPKGMEGTIDKIAA 3537
            I      D+ +Y C    +     TTA + V+G     + E Q   +P+   G ++ I +
Sbjct: 2233 ILTIDTSDAEDYSCVLVED-ENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVS 2291

Query: 3538 LEGYSG 3543
             E   G
Sbjct: 2292 PENIEG 2297



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 7/89 (7%)

Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIAS 1107
            PLK  N ++EG  A  E +V    D+T +V+WY N +QI   +R+Q         L I  
Sbjct: 2450 PLKDVN-VIEGTKAVLECKVSVP-DVT-SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINR 2506

Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
              A D G Y ++     G  + + +++VE
Sbjct: 2507 THASDEGPYKLI----VGRVETNCNLSVE 2531



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/179 (22%), Positives = 67/179 (37%), Gaps = 13/179 (7%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D +V EG     +C+V+      V W++ND QI+ D   + +V +     L+I     S
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV-KGTKQRLVINRTHAS 2510

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D G    +     G     C L+V   E++   K +     L   E + VV       + 
Sbjct: 2511 DEGPYKLIV----GRVETNCNLSV---EKI---KIIRGLRDLTCTETQNVVFEVELSHSG 2560

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA-QNVAGSTATRA 576
               + W      I P+ + +I   G    L +      D   Y   A +N+     T A
Sbjct: 2561 ID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVA 2618



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F+ +I+S  V E +   F C  +    P   + WY N   +P    +       +  
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQP--IVTWYNNDMPIPRNQNFIIHSLENYSI 4000

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            L +  V+ ++ G   C   N +G   T + +  K
Sbjct: 4001 LTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVK 4034



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/150 (20%), Positives = 62/150 (41%), Gaps = 6/150 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F  P+   +V EN    F   +   G P   V+W RN   +E   R+         +L
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEV--EGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSL 5240

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK----ASLQLESQHESALQKIQQLED 1826
             +  +   + G Y C A+N +GEA + + + +  +     +L     H+  ++   +   
Sbjct: 5241 EISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHTT 5300

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856
            SSR    +++ + V  + + + +     K+
Sbjct: 5301 SSRTPSPQEIVLEVELSEKDVKEFEKQVKI 5330



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 9/149 (6%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G + +   L  +AE+  PP F      + + + S    + R+  +   +  V+++ +G  
Sbjct: 87   GQATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAE 143

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            + +    +   +     L I   Y  D+G Y+  ATN  G AT + +L V+G      E 
Sbjct: 144  IQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EE 197

Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIE 3688
            ++P+       S  ++ E+   R E  IE
Sbjct: 198  EVPAKKTKTIVSTAQISESRQTRIEKKIE 226



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/109 (22%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V   T  P F   ++  +++++G     + R+   G  T  V++ +DG  +++S      
Sbjct: 97   VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQIS 153

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                  +L I      D+G Y+  A N++G+AT++A L +  ++++ A+
Sbjct: 154  QEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+S   + +G  V L+ +V     P +K  ++++G  + +    + + +  L +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L I     +DSG Y+  ATN +G A STA + ++
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY 4157
            RCPP F+   ++  V EG+   F C   G+P+P V W  N   I     +
Sbjct: 3941 RCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNF 3990



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 2/109 (1%)

Query: 2885 EAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLK 2944
            +A+ Q +  +  K R   + D     P+ +  +    +  EG  + LE  +    +P   
Sbjct: 4132 KAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLIS--GEPQPV 4189

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            + W+ NG +L+Q  +F+         L + DV  +DSG Y C A N  G
Sbjct: 4190 VTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSG 4238



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 2/106 (1%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            K   + + D    PP+   E+  +    EG  +  +C +   G+P   + WF NG     
Sbjct: 4144 KHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQ 4201

Query: 3741 GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
              +           L I  + ++D+G+Y C A N  G+  + + +T
Sbjct: 4202 NQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLT 4247



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/92 (28%), Positives = 42/92 (45%)

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            +GE   +++T    +   V   KI +  +N  + E  DA F V+L+      V W KNG 
Sbjct: 2686 IGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV 2745

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L ++ K+ I       +LR++N    D   Y
Sbjct: 2746 VLESNEKYAISVKGTIYSLRIKNCAIVDESVY 2777



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KDI+V E + A FE     V +P + V+W+++   ++ ++R+    +     L +
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLI 3116

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                  D+G YT  A    G  V+++ LFV+ +
Sbjct: 3117 PSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3145



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F+  ++S    EG   +F    +  G P   + W  N   I  +  F       Y  
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQ--GYPQPIVTWYNNDMPIPRNQNFIIHSLENYSI 4000

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + S++ Q+ G  TC   +  G  +T ++L V
Sbjct: 4001 LTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 18/150 (12%)

Query: 1165 PMYQIEEISKSKPVFVQPLSNPPP-----------VSEGKNIHLECRLEPMGDPTMRVEW 1213
            P  Q+ +  K + VF+  ++N PP             EG +I LEC +   G+P   V W
Sbjct: 4135 PQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTW 4192

Query: 1214 FHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273
            F NG  +    +F+         L I    S D+G+Y   A N+ G+  + + + V    
Sbjct: 4193 FQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTV---- 4248

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVRE 1303
            + VT  +N Q  E I  +     R +Q+++
Sbjct: 4249 EPVTYRENSQ-FENIGEIYGKYSRDQQLQD 4277



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 2233 EVEEPKIS--PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            E  EPK +  PP F+  L     V+E  T  F  +VE +  P   +++Y N   L+   R
Sbjct: 5172 EAIEPKDNEMPPSFIEPLT-KRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDER 5228

Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              +       SL+I +    + GEY   A+N +G   S  ++ +
Sbjct: 5229 IKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 5/133 (3%)

Query: 3183 IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++WY N   +    RIK         L+I+  Q  + GEY+C A N  GE  + A ++  
Sbjct: 5214 VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +    +    P +   + E +       +TPS     P + + +++   K V+      
Sbjct: 5274 PQEERVVALPPPVTHQHVMEFDLEHTTSSRTPS-----PQEIVLEVELSEKDVKEFEKQV 5328

Query: 3303 EARLVPVDDPDLK 3315
            +   VP   PD K
Sbjct: 5329 KIVTVPEFTPDHK 5341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 19/163 (11%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSG 3119
            +E Q   +E  L  +G   + + W +  K I+ S + + + A G +  L +L     D G
Sbjct: 2545 TETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEG 2600

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             Y+  A       +++V    + K    +            + + Q A FEC V    +P
Sbjct: 2601 KYTFYAGENITSGKLTVAGGAISKPLTDQT-----------VAESQEAVFECEVA---NP 2646

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            D K EW  +G+ +  +  I++ SD     L IA T+  D GEY
Sbjct: 2647 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY 2689



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 8/94 (8%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            F  H+K   K++E +    E +V   ++P++ ++W K+   L    R+K   +  +  L 
Sbjct: 3060 FRKHIKDI-KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLL 3115

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            I S R  D+G YT  A    G  VSTA + +E R
Sbjct: 3116 IPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3145



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            K++E + A FE  V   S+  +TV+W  + +++   +RI+   +     L I S R  D+
Sbjct: 3068 KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3124

Query: 1114 GVYTVVARNAAGEAQL 1129
            G YTVVA      A+L
Sbjct: 3125 GKYTVVAGGNVSTAKL 3140



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 4/94 (4%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPPK + ++    +  EG S   E  +    +P   V WF NG  L    +++ F +   
Sbjct: 4156 EPPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQ-FEEVNC 4212

Query: 3340 VI-LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
               L I     ++SG+Y+CVA N  G   + ++L
Sbjct: 4213 SHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDL 4246



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 7/135 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F +E      V E   + F   VE  G P   + W+ N        R+         
Sbjct: 5182 PPSF-IEPLTKRKVYENTTLGFIVEVE--GLPVPGVKWYRNKSLLEPDERIKMERVGNVC 5238

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE--L 3811
            +L+I  I   + GEY C A N  G A + A +    + + V+   LP  ++ + + E  L
Sbjct: 5239 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVV--ALPPPVTHQHVMEFDL 5296

Query: 3812 ERGRISDAPKEEPIV 3826
            E    S  P  + IV
Sbjct: 5297 EHTTSSRTPSPQEIV 5311



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 16/179 (8%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  P   T++ KDI +  E     +E ++   G   +  +W  NG  I+++ + +     
Sbjct: 2965 TVTPIMITSMLKDI-NAEEKDTITFEVTVNYEG---ISYKWLKNGVEIKSTDKCQMRTKK 3020

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L I      D+  Y+  A      A + V+   ++        F  HI++I+ L+ 
Sbjct: 3021 LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIE--------FRKHIKDIKVLEK 3072

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             + A FEC V    +PD+ ++W  + Q ++ + RIK   +     L I  T+  D+G+Y
Sbjct: 3073 -KRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKY 3127



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/95 (24%), Positives = 37/95 (38%)

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            ++ Q   P F++   +  V EG+         G P P +TW  + +PI  N    IH+  
Sbjct: 3937 KRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLE 3996

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              S L +      +     C   N  G+  T + L
Sbjct: 3997 NYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSML 4031



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 6/130 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++PL+        +N  L   +E  G P   V+W+ N   +    R K        +
Sbjct: 5183 PSFIEPLTKRKVY---ENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCS 5239

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI---ERSDIVTDTQNEQAIEQIQLLED 1293
            L+I +    + GEY   AVN +G A + A V ++   ER   +      Q + +  L   
Sbjct: 5240 LEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHT 5299

Query: 1294 AARRTKQVRE 1303
             + RT   +E
Sbjct: 5300 TSSRTPSPQE 5309



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 6/113 (5%)

Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALD 3756
            FT E++D +   +     F+C      +P +++ W+ +G     G +    +D     L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ---LPQGMSGE 3806
            I  I   DA +Y+C         TT   I   A  + V E Q   +P+  SGE
Sbjct: 2233 ILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGE 2285



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 2776 FISHLNNIVCKEGDNIH-FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            F   L ++V KE D +  FEC      +P +K++W+ +   +  G +Y+   D     L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTS 2860
            I      D+  Y+C     +   TT+
Sbjct: 2233 ILTIDTSDAEDYSCVLVEDENVKTTA 2258



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 8/84 (9%)

Query: 3433 REGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR---TFCDFGFVILEISPTYPED 3489
            REG++   E  ++   +P   V W+ NG  LK   +F+     C     I +++    +D
Sbjct: 4171 REGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNS---QD 4225

Query: 3490 SGEYLCRAYNNYGEAVTTASMKVQ 3513
            SG+Y C A NN G   + + + V+
Sbjct: 4226 SGKYKCVAENNSGAVESVSDLTVE 4249



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 7/144 (4%)

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            E  +P + E P   P F+  LT    + E     F   VE +  P   + W+ N   +  
Sbjct: 5172 EAIEPKDNEMP---PSFIEPLTK-RKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEP 5225

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
              R +        +L+I      + G YMC A N +GEA +   + +      ++    P
Sbjct: 5226 DERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPP 5285

Query: 2215 NGLEKIRQLEAQGHSTRIEVEEPK 2238
               + + + + + H+T      P+
Sbjct: 5286 VTHQHVMEFDLE-HTTSSRTPSPQ 5308



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F +P+   +V E   +     +  +  P   V+WY N   ++   R K        +L
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGL--PVPGVKWYRNKSLLEPDERIKMERVGNVCSL 5240

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +I      + G YMC A N +GEA + ++V +
Sbjct: 5241 EISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 11/147 (7%)

Query: 3670 ESIQKLEETLHKREEITIEDEKPN-----PPRFTVEIKDNID---VPEGGPVHFDCRVEP 3721
            E  ++ ++ L +  +ITI   KP+     P     +I + I    V +G   HF  RV  
Sbjct: 2044 ELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRV 2101

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
            VG P    +W+ NG       R++    +     L I  + A D+     +A N  G  +
Sbjct: 2102 VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETS 2161

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEK 3807
            + A +   AK+ I    +L   ++ EK
Sbjct: 2162 SHAFLLVQAKQLITFTQELQDVVAKEK 2188



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F K  +D  V E K   F+C V+  P   V W  +D++++     KI   E   H L+I
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQ-KEKYVHRLLI 3116

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAF----QCRLNVIEKEQVVAPK 492
             +  +SD+G  T VA  N S    F      R+  I+KE  V  K
Sbjct: 3117 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 3161



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 6/127 (4%)

Query: 1985 KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYA 2044
            K+A   EG  + LE  ++   +P   V W+ NG  ++Q  +F+         L I    +
Sbjct: 4166 KHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNS 4223

Query: 2045 EDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQ 2104
            +D+G Y C A N  G   + S + V+  +  Y +    + + +I    KY R + ++++ 
Sbjct: 4224 QDSGKYKCVAENNSGAVESVSDLTVEPVT--YRENSQFENIGEI--YGKYSRDQQLQDQG 4279

Query: 2105 PGQRPVF 2111
               R  F
Sbjct: 4280 ESVRAHF 4286



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 15/180 (8%)

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHF--ECRLIPVNDSSMRVEWFHNGKPL 3600
            GT +      ++  PP F    +   + EN++  F  E   +PV      V+W+ N   L
Sbjct: 5168 GTPNEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG----VKWYRNKSLL 5223

Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
                R+K         LEI  + + + G Y C A N  GEA     + +  ++  ++   
Sbjct: 5224 EPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALP 5283

Query: 3661 LPSHFKSGTESIQKLEETLHKR----EEITIEDE--KPNPPRFTVEIKDNIDVPEGGPVH 3714
             P   +   E    LE T   R    +EI +E E  + +   F  ++K  + VPE  P H
Sbjct: 5284 PPVTHQHVMEF--DLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVK-IVTVPEFTPDH 5340



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/97 (23%), Positives = 43/97 (44%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V+W ++   +E   RI         +L I ++   + G Y C A N IG+A + AN+ I+
Sbjct: 5214 VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKI 1039
             +++ +     P   + +   +     S RT    +I
Sbjct: 5274 PQEERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEI 5310



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I  L ++ C E  N+ FE  +  S    + + W F +K +   ++YK         L + 
Sbjct: 2536 IRGLRDLTCTETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVL 2592

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            +  ++D G YT  A    G   TSG L   G
Sbjct: 2593 NMMKDDEGKYTFYA----GENITSGKLTVAG 2619



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 7/97 (7%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFG- 2698
            P FT  L ++  ++EG+ V    ++     P +   WF N   + TG R  +K+  D   
Sbjct: 3504 PSFTQKL-TFKYVLEGEPVVFTCRLIACPTPEMT--WFHNNRPIPTGLRRIIKAESDLHH 3560

Query: 2699 -LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
               +L I  +++ DSG Y   A N  G A STAS+ +
Sbjct: 3561 HSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 30/118 (25%), Positives = 45/118 (38%), Gaps = 5/118 (4%)

Query: 3019 TEGLEKIQNLEDSLRKEPGQQ---PDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPT 3075
            TE LE     +D + + P  +     D T  PP+            EG     E  +  +
Sbjct: 4126 TEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLI--S 4183

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            G+   V+ WF NG  ++ + + +         L I    + DSG Y C A N  G  E
Sbjct: 4184 GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVE 4241



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 1846 FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALD 1905
            F+ +L    ++ E  S   EC + P    N+  +WY N   L+S  +Y  ++  G   L 
Sbjct: 2269 FVKELQD-IEVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 1906 ILTVYGEDSGEYT 1918
            +  V  ED GEY+
Sbjct: 2325 VKDVTKEDQGEYS 2337



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            +   TV ES+   FEC V    +P  + EW R+GK LP  +  R+  D     L I    
Sbjct: 2626 LTDQTVAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATK 2682

Query: 3896 AEDSGEY 3902
             +D GEY
Sbjct: 2683 LDDIGEY 2689



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            ++E Q A +EC +    +P+ + EW  +GK L   +  R+ +D     L I     +D G
Sbjct: 2631 VAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIG 2687

Query: 1916 EYTCKAINNLGQA---VSSIRLNVQSKESIIRDSQ 1947
            EYT K   +   A   V ++++    K   + ++Q
Sbjct: 2688 EYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQ 2722



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EGQ    + +V   TD  LK+ W+     +      + T       L I     +D G Y
Sbjct: 3358 EGQPARFQCRVSG-TD--LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 3414

Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESLHPD 2748
            T  A+N +G+  STA++ +E    +L E +  +
Sbjct: 3415 TFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            P F   I++ E + +G S +F C       P   + WY+N  P+  +      S   + +
Sbjct: 3944 PSFLQEIESQE-VYEGDSCNFVCHFQGYPQPI--VTWYNNDMPIPRNQNFIIHSLENYSI 4000

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244
            L ++   + + G   C  +N+YG   T + +    K
Sbjct: 4001 LTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAK 4036



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 5/133 (3%)

Query: 1277 TDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQP 1336
            T+    +A+ Q Q+ +    R   +  DIT            +    EG ++ LEC +  
Sbjct: 4126 TEELEPKAMPQDQVTQSPKHRFVFL-SDITNEPPKMLQEMPKHARCREGDSIILECLIS- 4183

Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG--EA 1394
             G+    V WF NG  +K   +F+         L +  V  +DSG Y C A N  G  E+
Sbjct: 4184 -GEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVES 4242

Query: 1395 VTSCALRVIAKKD 1407
            V+   +  +  ++
Sbjct: 4243 VSDLTVEPVTYRE 4255



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/88 (25%), Positives = 37/88 (42%), Gaps = 2/88 (2%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            +T + P   Q +      +EG +   +C +   G+P   V WF+N  L++ + +      
Sbjct: 4153 ITNEPPKMLQEMPKHARCREGDSIILECLIS--GEPQPVVTWFQNGVLLKQNQKFQFEEV 4210

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                 + I  V  +D G Y C A N  G
Sbjct: 4211 NCSHQLYIKDVNSQDSGKYKCVAENNSG 4238



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/59 (33%), Positives = 29/59 (49%)

Query: 3454 VEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            V+WY N   L+   R +         LEIS     + GEY+C A N  GEA + A++ +
Sbjct: 5214 VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++  +++G       R+   G PT  V+++R+   I+ S     + +    S
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+    ED G Y   A+N +G
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVG 183



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 765  QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824
            Q  Q   F + LQD+   ++   A FE +    S+P ++V+WYKDG  +    +     +
Sbjct: 2169 QAKQLITFTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSD 2225

Query: 825  FGYVSLNIMHLRAEDAGSYT 844
                 L+I+ +   DA  Y+
Sbjct: 2226 RKVHFLSILTIDTSDAEDYS 2245



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 7/143 (4%)

Query: 3559 EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILE 3618
            EF     D+ + E+ S   EC + P N   +  +W+HN   L +  +    +  G   L 
Sbjct: 2268 EFVKELQDIEVPESYSGELECIVSPEN---IEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 3619 IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEET 3678
            +  V + D G Y+       G+ T +CKL++K R   IL+         G     +++ +
Sbjct: 2325 VKDVTKEDQGEYSFVI---DGKKT-TCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS 2380

Query: 3679 LHKREEITIEDEKPNPPRFTVEI 3701
            L   E + ++D +   P   V I
Sbjct: 2381 LESVEGVWMKDGQEVQPSDRVHI 2403



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100
            + P+ L  +    +  EG S   E  +  +    +T  W+ NG  +    + Q       
Sbjct: 4156 EPPKMLQEMPKHARCREGDSIILECLISGEPQPVVT--WFQNGVLLKQNQKFQFEEVNCS 4213

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
              L I  V ++DSG Y  VA N +G  +  + +TVE
Sbjct: 4214 HQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVE 4249



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM-IHEGNNAVLLIGNTYE 4785
            +++  + EG    F  +++    P I W ++G  I     +QM   +   A L I     
Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLP 1356

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            ED G +T  A+   G    S KL V+
Sbjct: 1357 EDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 2122 KEGDR-AHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            KE D  A FEC     ++P + + W+ +G ++  G +YR   D     L IL     D+ 
Sbjct: 2186 KEKDTMATFECET---SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAE 2242

Query: 2181 TYMC 2184
             Y C
Sbjct: 2243 DYSC 2246



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            F + LQ+I+ + E  +   +C + P     ++ +W+ N+  ++ + + T T   G  ++T
Sbjct: 2269 FVKELQDIE-VPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 2438 ISHVRDEDEGVY 2449
            +  V  ED+G Y
Sbjct: 2325 VKDVTKEDQGEY 2336



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 910  EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
            EF+  IKD I + E   A FE     + +  + V+W+KD + ++ + RI          L
Sbjct: 3059 EFRKHIKD-IKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRL 3114

Query: 970  TIKSVTVHDAGHYTCRAYNAIGQA 993
             I S  + DAG YT  A   +  A
Sbjct: 3115 LIPSTRMSDAGKYTVVAGGNVSTA 3138



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/51 (31%), Positives = 24/51 (47%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            V+WY N   L+   R          +L+I +    + G Y C A+N +GEA
Sbjct: 5214 VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEA 5264



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            + + P F   +Q V  L EG +A FEA +     P+  V WF +G+ +           F
Sbjct: 2    TTQAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISF 58

Query: 3338 --GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              G   L I    + NSG Y   ATN  G+ ++ A L
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/123 (21%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            +++ ++ T  P FV R +S+  V +G  V  + ++  +    +K  ++++G  +     F
Sbjct: 94   ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDF 150

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEAGL 1552
            +   +    +L I +   EDSG Y+  A N VG    +  L  +   ++  + T+     
Sbjct: 151  QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVST 210

Query: 1553 EQI 1555
             QI
Sbjct: 211  AQI 213



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADT 1247
            + EG  +   C++   G P  ++ W+ +G+ +  G R++  +   G  +L I      D 
Sbjct: 1302 ILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDE 1359

Query: 1248 GEYTVRAVNHLGSA 1261
            G YT  A N  G+A
Sbjct: 1360 GIYTAFASNIKGNA 1373



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P  I Q   + K+ EG   Q +V++S      V W K+GQ +  S++  I+       L 
Sbjct: 2355 PIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLL 2413

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            + +  K D+G+Y+     P   + TSG ++V S
Sbjct: 2414 IEDMTKEDAGNYSFTI--PALGLSTSGRVSVYS 2444



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 8/119 (6%)

Query: 4700 SAGRVTVAAKLKVTQPDQADNL--PA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            S  R++   +L+ T   Q + L  P   L P+      EGQ A+F  ++  +  P   W 
Sbjct: 1433 SPARMSPGRRLEETDESQLERLYKPVFVLKPV-SFKCLEGQTARFDLKVVGRPMPETFWF 1491

Query: 4756 REGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +G  I      +++   +G  +++++  T   D+G +T  A   AG+   S  L V++
Sbjct: 1492 HDGQQIVNDYTHKVVIKEDGTQSLIIVPAT-PSDSGEWTVVAQNRAGRSSISVILTVEA 1549



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 774  RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIM 833
            +PL D   + E + A FE +   V++P  + EW +DG+ +  ++ I S  +     L I 
Sbjct: 2624 KPLTDQ-TVAESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIA 2679

Query: 834  HLRAEDAGSYTVR-AVNKLGEAISTASIRV 862
              + +D G YT + A +K    +   ++++
Sbjct: 2680 ATKLDDIGEYTYKVATSKTSAKLKVEAVKI 2709



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 2245 VTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDI 2304
            +T+      V E KTA FEC+V   + P++ ++   NG  ++ + +F I        L I
Sbjct: 2884 ITKTMKNIEVPETKTASFECEVSHFNVPSMWLK---NGVEIEMSEKFKIVVQGKLHQLII 2940

Query: 2305 QHCVPEDAGEYS 2316
             +   ED+ EY+
Sbjct: 2941 MNTSTEDSAEYT 2952


>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
          Length = 30000

 Score =  294 bits (722), Expect = 4e-78
 Identities = 268/1028 (26%), Positives = 456/1028 (44%), Gaps = 98/1028 (9%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY---RTVYDMGF 3886
            P F+ ++K+  ++E  G + E +V    +P   I W +N  ++   H+Y   R     G 
Sbjct: 1556 PMFVEKLKNVNIKE--GSQLEMKVRATGNPNPDIVWLKNSDIIVP-HKYPKIRIEGTKGE 1612

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK---KLPDIILQNQVPRGMKRSE-- 3941
             +L I    ++DS  Y   A+N  G D T+  ++ +     P+   +  +PRG  R++  
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 3942 ALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVG 4001
            A  ++E    +Y  E +  E DLYD +K+Q P F  ++ S   L       FEC+L P+G
Sbjct: 1673 AAPELEPLHLRYGQEQW-EEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPIG 1730

Query: 4002 DPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
            DP M VEW  +GKPL   NR   I +FGY ++++G  Y  DSG   CRATN YG D T A
Sbjct: 1731 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1790

Query: 4062 VIKTTGKPGIVYDSQLPKHMKSIEKIREMEA-SWQVTPEQVVEESKARCPPVFVSLPDAV 4120
             +    +  +V +SQLP+  K +++I E+E  + +     V  + K +  P  V  P+ V
Sbjct: 1791 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1850

Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGKI 4180
             V EGE ARF CRVTG+P+P+V W LNG  I    R+++ YDG+++ DI   + YDTG++
Sbjct: 1851 RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEV 1910

Query: 4181 EVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYD-ETTQYQRTETELEK------ 4233
            +V              L++  R +D+R VL+ AP P  +    +  + + E++K      
Sbjct: 1911 KVTAENPEGVIEHKVKLEIQQR-EDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVD 1969

Query: 4234 TFEERQV--LQRQGVIDHRP------ELKPKVIKEPETEWQQSV------KRKKNEEYYN 4279
            T E ++V  L+R   I H        EL+ K  +  E  + +++       RKK+E Y  
Sbjct: 1970 TTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEE 2029

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQT---EEVTEQR 4336
             L++ ++E +     L E   +      K+T  T      +    +++     E +  Q 
Sbjct: 2030 LLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIE-LSPSMEAPKIFERIQSQT 2088

Query: 4337 VQKKVTQKPRI-----PDPSESTVHGKEVHVAKQKQTQKEVVGDKE---ITRKITSTETT 4388
            V +      R+     PDP E   +   V + +  +       D     + R +T+ ++ 
Sbjct: 2089 VGQGSDAHFRVRVVGKPDP-ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSA 2147

Query: 4389 EIEHKAQTQERVVEGP----VKPSKPPIFTKKMQPCRVFEHE-QARFEVEFDGEPLPLIK 4443
             I  KA              V+  +   FT+++Q     E +  A FE E   EP   +K
Sbjct: 2148 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECE-TSEPFVKVK 2206

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            WY++   +     +++H+      L I  +   D+  ++ V        K +A L+VE  
Sbjct: 2207 WYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE-DENVKTTAKLIVE-- 2263

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                 G +V   F    Q++ V       L+  +   + I+  W  N  +++ + +  I 
Sbjct: 2264 -----GAVV--EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTIT 2315

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623
               G   L + +   +D G+Y  V      +  C           K K KP+      P 
Sbjct: 2316 SRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTC-----------KLKMKPR------PI 2356

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
             I++ L D+ V EG  ++   K+  + +  V W K  + ++PS    +      + L I 
Sbjct: 2357 AILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIE 2415

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
            +   ED G+Y       A  ++ + ++ V   D       +TPL+D+ V EG  A  + +
Sbjct: 2416 DMTKEDAGNYSFTI--PALGLSTSGRVSVYSVD------VITPLKDVNVIEGTKAVLECK 2467

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            ++     +++W      I      Q I +G    L+I  T+  D G +        G+VE
Sbjct: 2468 VSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY----KLIVGRVE 2523

Query: 4804 TSAKLVVK 4811
            T+  L V+
Sbjct: 2524 TNCNLSVE 2531



 Score =  257 bits (630), Expect = 6e-67
 Identities = 163/511 (31%), Positives = 249/511 (48%), Gaps = 14/511 (2%)

Query: 377  RETEERIEIS-EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            R  EE  E   E+   P FV         EG+  RFD +V GRP PE  WF + +QI +D
Sbjct: 1441 RRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVND 1500

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
            Y HK+++ E G  +L+I   T SDSG  T VA+N++G ++    L V   E  V P FVE
Sbjct: 1501 YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560

Query: 496  RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN--PELRIHTDGGASTLDIPRA 553
            +   +N++EG  + +  RA G P P I W K+   I+P+  P++RI    G + L I   
Sbjct: 1561 KLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDST 1620

Query: 554  KASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXX 613
             + D+AWY  TA N AG   TR ++           +++L +PR T              
Sbjct: 1621 VSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPL 1680

Query: 614  YLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            +LR+ +         ++++    P F   L S+     G  HFE R+ P+GDPTM +EWL
Sbjct: 1681 HLRYGQEQWEEGDLYDKEK-QQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWL 1739

Query: 674  KNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             +G+ +EA++R   I  FGY SLD      +DSG  TCRA +  G   T A L V    +
Sbjct: 1740 HDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKS 1799

Query: 734  IERTSQHPETLQYIQQLEDYSKYQHQESI-----EEQTSQRPQFIRPLQDLGELQEGRNA 788
            +   SQ PE  + +Q++E+  +  H+ ++     +++  Q+P  +   + +  L EG  A
Sbjct: 1800 LVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVL-EGETA 1858

Query: 789  HFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAV 848
             F  ++T    P  +V WY +G+ I  S R    ++ G   L+I+  ++ D G   V A 
Sbjct: 1859 RFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAE 1915

Query: 849  NKLGEAISTASIRVAARSTVTADL-GIPEQR 878
            N  G       + +  R    + L   PE R
Sbjct: 1916 NPEGVIEHKVKLEIQQREDFRSVLRRAPEPR 1946



 Score =  188 bits (457), Expect = 6e-46
 Identities = 221/822 (26%), Positives = 347/822 (42%), Gaps = 106/822 (12%)

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTN-KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
            R  +  E +++   KP F+  LK  + K +EGQ+A F+ +V  +  +  T  W+ +G+QI
Sbjct: 1442 RLEETDESQLERLYKPVFV--LKPVSFKCLEGQTARFDLKVVGRP-MPETF-WFHDGQQI 1497

Query: 1087 TS--ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTS 1144
             +   +++    D G  +L I      DSG +TVVA+N AG + +S  +TVE        
Sbjct: 1498 VNDYTHKVVIKED-GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA------- 1549

Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPM 1204
                        +E    V+PM+    + K K V ++         EG  +  E ++   
Sbjct: 1550 ------------VEHQ--VKPMF----VEKLKNVNIK---------EGSQL--EMKVRAT 1580

Query: 1205 GDPTMRVEWFHNGRSVTVGS--RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAH 1262
            G+P   + W  N   +      + +     G  AL I    S D+  YT  A+N  G   
Sbjct: 1581 GNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDT 1640

Query: 1263 TSAIVRV--------IERSDIV---TDTQNEQAIEQIQLLEDAARRTKQVREDI---TVM 1308
            T   V V         ER  I+   T    E A  +++ L     + +    D+      
Sbjct: 1641 TRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQ 1700

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P F + L ++        H ECRL P+GD TM VEW  +GKP++  +R R   EF Y 
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1760

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            +LD    Y  DSG+ TC+ATN+ G   TS  L V  +K L+ ESQ P G + +Q +E+  
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELE 1820

Query: 1429 RYKKTDII-----DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN 1483
            R      +     D+    KP  V  P+ +  V+EG+   F C++        KV W+ N
Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLN 1877

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            GQ +    RFR  +D G   LDI+D  + D+G     A N  G  E   +L  +   D  
Sbjct: 1878 GQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF- 1935

Query: 1544 RSTQNEA--GLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKN-VEIKEGQRAHFERR 1600
            RS    A     +  V E          VD      P+ TT  K  V++K  +R   E+ 
Sbjct: 1936 RSVLRRAPEPRPEFHVHEPGKLQFEVQKVDR-----PVDTTETKEVVKLKRAERITHEK- 1989

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNF-GFVALDIMSCLPEDSGTYTCRAINALG 1659
             +P     L+ ++           R TE   +    A+++ S   ++S     R      
Sbjct: 1990 -VPEESEELRSKF----------KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-- 2036

Query: 1660 EAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKD 1719
                    ++H  K   L  + + AL    ++     ++    +     +AP     ++ 
Sbjct: 2037 -------ELLHWTKE--LTEEEKKALAEEGKI-TIPTFKPDKIELSPSMEAPKIFERIQS 2086

Query: 1720 IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPE 1778
              V +   AHF  R+  VG P    EW +NGV IE S+R+        V  L ++ V  E
Sbjct: 2087 QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2144

Query: 1779 DSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
            DS +   +AIN  GE  + + L VQ+K  +    + +  + K
Sbjct: 2145 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2186



 Score =  187 bits (455), Expect = 1e-45
 Identities = 178/649 (27%), Positives = 283/649 (43%), Gaps = 60/649 (9%)

Query: 3293 KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT-FHDFGIVILDILYCYEEN 3351
            +++EG    F  ++     P  K+ W+ +GK++ HG RY+  F   G   L I     E+
Sbjct: 1301 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358

Query: 3352 SGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTS 3411
             G Y   A+N       K N  C+ K  L ++   P G       + TLE   V R  + 
Sbjct: 1359 EGIYTAFASN------IKGNAICSGK--LYVEPAAPLGAP---TYIPTLEP--VSRIRSL 1405

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTP------TDDPNL----KVEWYWNGK 3461
                  ++P+   P + +   R        AR++P      TD+  L    K  +     
Sbjct: 1406 SPRSVSRSPIRMSP-ARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV 1464

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            S K         D   V   +  T+    G+ +    N+Y   V    +K  G +++I+ 
Sbjct: 1465 SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV---NDYTHKVV---IKEDGTQSLIIV 1518

Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEA-ESGNPPEFTTTPSDLILSENSSAHFECR 3580
               P              G S     LT EA E    P F     ++ + E S    + R
Sbjct: 1519 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVR 1578

Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGS--RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
                 + +  + W  N   ++     +++     G   L+I     +D+  YT  A N+ 
Sbjct: 1579 A--TGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1636

Query: 3639 GEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE----ETLHKR------EEITIE 3688
            G  T  CK+ V+  +    EP+       GT   +++     E LH R      EE  + 
Sbjct: 1637 GRDTTRCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1695

Query: 3689 D-EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            D EK   P F  ++  ++ +   GP HF+CR+ P+GDPTM ++W H+G+P    +R+  +
Sbjct: 1696 DKEKQQKPFFKKKLT-SLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMI 1754

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSG-E 3806
            N+FG+ +LD    Y+RD+G  TCRATNK+G+  T+A +    ++ +V ESQLP+G  G +
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQ 1814

Query: 3807 KIKELER----GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            +I+ELER    G ++    ++      P  +   +   V E E  RF CRV     PK  
Sbjct: 1815 RIEELERMAHEGALTGVTTDQK-EKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPK-- 1871

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            + WY NG+L+    R+R  YD G   LDI+   + D+GE    A N  G
Sbjct: 1872 VNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1919



 Score =  174 bits (424), Expect = 6e-42
 Identities = 156/534 (29%), Positives = 234/534 (43%), Gaps = 64/534 (11%)

Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488
            R ++TD        KP FV +P S +  +EGQ   F+ K+  V     +  WF +GQ + 
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFK-CLEGQTARFDLKV--VGRPMPETFWFHDGQQIV 1498

Query: 1489 IGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
              +  +  I + G  +L I+     DSG +T  A                         Q
Sbjct: 1499 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVA-------------------------Q 1533

Query: 1548 NEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEGQRAHFERRLIPVSD 1606
            N AG   I V+           V+ V  Q  P+    LKNV IKEG +   E ++    +
Sbjct: 1534 NRAGRSSISVILT---------VEAVEHQVKPMFVEKLKNVNIKEGSQ--LEMKVRATGN 1582

Query: 1607 ATLKVEWYHNNKPLKSGS--RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                + W  N+  +      +       G  AL I S + +DS  YT  AIN  G   T 
Sbjct: 1583 PNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1642

Query: 1665 GIAIVH--------SKKSIYLESQH---EGALPRLNQLE---DTSKYQRHSAQDEVITQA 1710
                V          +K I     +   E A P L  L       +++     D+   Q 
Sbjct: 1643 CKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQK 1702

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +  +R+     AHFE RL P+GDP + VEWL +G P+EA+NRL  +++FGY +L
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1762

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
            +       DSG  TCRA N+ G   TS+TL V+ + SL  ESQ     + +Q++E+  R 
Sbjct: 1763 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1822

Query: 1831 QRREDVE-VAVNQAPR---FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                 +  V  +Q  +    I     P ++ EG++A + CR+  YP P  +V WY NG++
Sbjct: 1823 AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQL 1880

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++   R+R   D G   LDI+     D+GE    A N  G     ++L +Q +E
Sbjct: 1881 IRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1933



 Score =  165 bits (402), Expect = 3e-39
 Identities = 136/477 (28%), Positives = 216/477 (45%), Gaps = 33/477 (6%)

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            EGQ A ++  ++  G       WF++G+ I  + +H++  +   G   L I+    +DSG
Sbjct: 1470 EGQTARFDLKVV--GRPMPETFWFHDGQQIVNDYTHKV-VIKEDGTQSLIIVPATPSDSG 1526

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             ++  A N+ G++ ISV L         KP F   ++N+  +K+G  +  E  V    +P
Sbjct: 1527 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNV-NIKEG--SQLEMKVRATGNP 1583

Query: 3180 DMKIEWYHNGQ---PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
            +  I W  N     P ++  +I+     G   L I  T + DS  Y   A NK G D TR
Sbjct: 1584 NPDIVWLKNSDIIVPHKY-PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1642

Query: 3237 ATINC---YGKGGVYLESLQPDSLAKIRELES-------LQGAQQQTPSTPSAEPPK--- 3283
              +N    + +     + + P    + +E+ +       L+  Q+Q       +  K   
Sbjct: 1643 CKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQK 1702

Query: 3284 -FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
             F  +     +L     AHFE RL P+ DP + VEW ++GK L   +R R  ++FG   L
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1762

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG--GLEKLQTL 3400
            D    Y  +SG   C ATNK G D T A L    +++L+ +SQLP G +G   +E+L+ +
Sbjct: 1763 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1822

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
                     T+ ++EK K  +   P      + EGE A F  R+T    P  KV WY NG
Sbjct: 1823 AHEGALTGVTTDQKEKQKPDIVLYP--EPVRVLEGETARFRCRVTGYPQP--KVNWYLNG 1878

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
            + ++   RFR   D G   L+I      D+GE    A N  G       +++Q + +
Sbjct: 1879 QLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1934



 Score =  162 bits (393), Expect = 3e-38
 Identities = 166/643 (25%), Positives = 270/643 (41%), Gaps = 50/643 (7%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSY--VS 2832
            +F+  L N+  KEG  +  E  V  + +P   I W  N+  +      K   + +    +
Sbjct: 1557 MFVEKLKNVNIKEGSQL--EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1614

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLE------- 2885
            L I  T  +DS  YT  A N  G  TT    RC  +  + F    P+ K  +        
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTT----RCKVNVEVEFAEPEPERKLIIPRGTYRAK 1670

Query: 2886 --AVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKN 2939
              A  + E   L  G+        Y K +   P   +     +L      H E ++ P  
Sbjct: 1671 EIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIG 1730

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            DP + +EW  +GK LE  +R ++ ++FG+ +LD    Y RDSGI TC+A NK G   TS+
Sbjct: 1731 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1790

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKE--PGQQPDDDTGRPPEFTTVFKDI 3057
            T+    + +L+E +Q P+G +GL++I+ LE    +    G   D    + P+   ++ + 
Sbjct: 1791 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEP 1849

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V + EG+ A +   +  TG     + W+ NG+ I  S R R  Y  G+  L+I+  K+ D
Sbjct: 1850 VRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYD 1906

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKS-------KGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            +G     A N  G  E  VKLE   +        +  +PR   H+     L+      FE
Sbjct: 1907 TGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQ------FE 1960

Query: 3171 CTVV--PVDDPDMK-IEWYHNGQPMRHSTRIKTVSDFGFVV---LDIAYTQNHDSGEYVC 3224
               V  PVD  + K +      + + H    +   +         +  Y +   + E   
Sbjct: 1961 VQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKS 2020

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            R  ++  E+  R T +        L   +  +LA+  ++        +   +PS E PK 
Sbjct: 2021 RKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKI 2080

Query: 3285 ITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR-YRTFHDFGIVILD 3343
              +IQ  T + +G  AHF  R+V   DP+   EW+ NG K+    R Y  + +  +  L 
Sbjct: 2081 FERIQSQT-VGQGSDAHFRVRVVGKPDPE--CEWYKNGVKIERSDRIYWYWPEDNVCELV 2137

Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQL 3386
            I     E+S      A N  G  S+ A L   +K+ +    +L
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQEL 2180



 Score =  157 bits (380), Expect = 1e-36
 Identities = 119/421 (28%), Positives = 194/421 (46%), Gaps = 33/421 (7%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV--QQGHRFKTTYDFGY 2034
            KP F + +KN  + EG  + ++   T   +P   + W  N   +   +  + +     G 
Sbjct: 1555 KPMFVEKLKNVNIKEGSQLEMKVRAT--GNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE 1612

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG------LYLDTLDEQRLKKI 2088
             AL I    ++D+  Y   A N  G   T   V V+ +          +      R K+I
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 2089 Q--ELE----KYERPK----PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPIND 2138
               ELE    +Y + +     + +++  Q+P F   LTSL  LK    AHFECR+ PI D
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLR-LKRFGPAHFECRLTPIGD 1731

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P + ++W H+G+ + A +R R  ++FGY +LD    Y+ DSG   C+ATNK G    + T
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791

Query: 2199 LKVAGHRNIILDTQHP---NGLEKIRQLEAQGHS---TRIEVEEPKISPPRFVTELRGTT 2252
            L V   ++++ ++Q P    GL++I +LE   H    T +  ++ +   P  V       
Sbjct: 1792 LIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVL-YPEPV 1850

Query: 2253 HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDA 2312
             V EG+TA F C+V     P  ++ +Y NG+ ++ + RF + +D G   LDI  C   D 
Sbjct: 1851 RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1907

Query: 2313 GEYSVKAINALGHCTSAISMTVTAKGSIISESQR-PEGLEKIRELESAE-PFKRPEIPEP 2370
            GE  V A N  G     + + +  +    S  +R PE   +    E  +  F+  ++  P
Sbjct: 1908 GEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRP 1967

Query: 2371 V 2371
            V
Sbjct: 1968 V 1968



 Score =  155 bits (375), Expect = 5e-36
 Identities = 108/404 (26%), Positives = 166/404 (41%), Gaps = 31/404 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP F +K++            E    G     + W+++   I + P  Q         L 
Sbjct: 7667 PPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLN 7726

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  +   D+ ++  VA N  G+ +CSA L V+E          PPSF  T  +V V  G 
Sbjct: 7727 LSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE----------PPSFEQTPDSVEVLPGM 7776

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +   + + GT P  V W K  +++ P     I  ED    L + E  P +SG Y C+  
Sbjct: 7777 SLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVT 7836

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG A C     V  PAT                 ++ L D  V  G  I       G 
Sbjct: 7837 NDAGSASCTTHLFVKEPAT----------------FVKRLADFSVETGSPIVLEATYTGT 7880

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P  +V W K + LI  S+   ++ T     L I E+  ED   Y C+  N AG+    A 
Sbjct: 7881 PPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEAL 7940

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            + V +P        + PL  +    G+PA  + ++    +  I W +E   +   P ++M
Sbjct: 7941 VSVLEPPYF-----IEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKM 7995

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              + N A L+I      D G ++C+A  + G V +SA LV+K +
Sbjct: 7996 QFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKER 8039



 Score =  155 bits (375), Expect = 5e-36
 Identities = 108/413 (26%), Positives = 195/413 (47%), Gaps = 26/413 (6%)

Query: 4400 VVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI 4459
            + E  V   +PP F + ++       E A  + + DG P   I WY+E+  ++++P +++
Sbjct: 7936 ICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKM 7995

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
               +  + L+I +V   D   ++  A+N  G    SA LV++E++       +PP F   
Sbjct: 7996 QFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERK-------LPPFFARK 8048

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             ++V+ T G  V  + ++ G++P+ V W K+G  ++ D   +        TL IL+    
Sbjct: 8049 LKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQS 8108

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQ 4638
              G+Y C A N  G A   A+ ++S                 PP   ++P+   + A G+
Sbjct: 8109 HIGQYNCSASNPLGTASSSAKLILS-------------EHEVPPFFDLKPVSVDL-ALGE 8154

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            +  F C + G     + W K ++ I+P   ++M+   +  TL + +    D G Y C A 
Sbjct: 8155 SGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYAS 8214

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
            N AG+ + +A L V +P +   +  L P R  +V + +  +++ +I    +  + W ++ 
Sbjct: 8215 NIAGKDSCSAHLGVQEPPRF--IKKLEPSR--IVKQDEFTRYECKIGGSPEIKVLWYKDE 8270

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              I E+  F+M    + AVL + N   ED+G +TC A  AAG   +S  L VK
Sbjct: 8271 TEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 8323



 Score =  154 bits (374), Expect = 7e-36
 Identities = 119/453 (26%), Positives = 195/453 (43%), Gaps = 39/453 (8%)

Query: 4375 DKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEF 4434
            D+ +  + + T T  I   + +   ++    +   PP F  ++ P      E A FE   
Sbjct: 9047 DRSLAGQYSCTATNPIGSASSSARLIL---TEGKNPPFFDIRLAPVDAVVGESADFECHV 9103

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
             G     + W +++  I++   +QI      + L + +V   DS  +   A N  G   C
Sbjct: 9104 TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSC 9163

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
            +A L ++E+       ++PPSFT   ++ V  T G   +L+ +V G++PI V W KN  +
Sbjct: 9164 TAQLNIKER-------LIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIE 9216

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +QP    +I  ++ T  L + +A   D+G Y C   N AG A C +  V+  P       
Sbjct: 9217 IQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEP------- 9269

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                    PP   + L    V+EG+ ++ SC + G     +QW K  + IKPS     S 
Sbjct: 9270 ------KKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSF 9323

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA---------- 4723
             +    L + +    D GDY C A N AG  T   K KVT  D+    PA          
Sbjct: 9324 ASGTAVLELRDVAKADSGDYVCKASNVAGSDT--TKSKVTIKDKPAVAPATKKAAVDGRL 9381

Query: 4724 --LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE-GNNAVLLI 4780
              ++  + I V E   A F  ++     P ++W +             IH+ G+ A L I
Sbjct: 9382 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEI 9441

Query: 4781 GNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +T + D+G + C A    G++E++  L V  +
Sbjct: 9442 RDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 9474



 Score =  153 bits (372), Expect = 1e-35
 Identities = 109/435 (25%), Positives = 194/435 (44%), Gaps = 28/435 (6%)

Query: 4379 TRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438
            T++     + EIE++A     V    V   +PP F  +++P      +    + +  G P
Sbjct: 6976 TKRDAGQYSCEIENEAGRD--VCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTP 7033

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
               + WY+ +  ++ +P+++ +  +  + L+  +V + DS  +   AEN  GTA      
Sbjct: 7034 EITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVF 7093

Query: 4499 VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDI 4558
             ++E++       +PPSF    +++  T G  V L  ++ G+ PI V W ++G  ++ D 
Sbjct: 7094 RIQERQ-------LPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDE 7146

Query: 4559 RNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKA 4618
              +    D   TL IL+     SG+Y C A N  G A   A        T  +PK     
Sbjct: 7147 NLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSAR------LTAREPK----- 7195

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
              +P   I+P+   ++A G++ +F C + G     + W K +K I+P   + ++   +  
Sbjct: 7196 -KSPFFDIKPVSIDVIA-GESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 7253

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ-ADNLPALTPLRDIVVYEGQP 4737
             LRI +    D G Y C A N  G+   +A+L V +P +    L A       V  +G+ 
Sbjct: 7254 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEA-----SKVAKQGES 7308

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
             Q + +I+   +  + W R  + + E+  + M    + A+L I     ED+G + C A  
Sbjct: 7309 IQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHN 7368

Query: 4798 AAGQVETSAKLVVKS 4812
              G    S  L VK+
Sbjct: 7369 GVGDASCSTALTVKA 7383



 Score =  153 bits (371), Expect = 2e-35
 Identities = 106/407 (26%), Positives = 184/407 (45%), Gaps = 29/407 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP F K+++P +V   + A  + +  G P   + WY+ +  ++ +  +++H  +  + L
Sbjct: 8886 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8945

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +  QV + DS  +   AEN  G    S  L V+E++       +PPSF+   ++V  T G
Sbjct: 8946 VFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK-------LPPSFSRQLRDVQETVG 8998

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGK--KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
              V  D  ++G++PI V W K+GK  K  P+++   L  D T TL I +     +G+Y C
Sbjct: 8999 LPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFL--DNTATLNIFKTDRSLAGQYSC 9056

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
             A N  G A   A  ++    T+ K  P      AP        D +V  G++ +F C +
Sbjct: 9057 TATNPIGSASSSARLIL----TEGKNPPFFDIRLAP-------VDAVV--GESADFECHV 9103

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G     V W K  + I+    +Q+S   +   L + +    D G Y C A N  G+ + 
Sbjct: 9104 TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSC 9163

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ--ITSKIKPTIQWLREGALIPET 4764
             A+L + +       P+ T      V E +   FK +  +      T+ W +    I  T
Sbjct: 9164 TAQLNIKERLIP---PSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPT 9220

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             + ++  + N  VL +      D G +TC+ +  AG    ++ +V+K
Sbjct: 9221 SNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 9267



 Score =  153 bits (370), Expect = 2e-35
 Identities = 172/672 (25%), Positives = 280/672 (41%), Gaps = 59/672 (8%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASS-- 817
            E++E Q   +P F+  L+++  ++EG  +  E ++    +P   + W K+   I      
Sbjct: 1548 EAVEHQV--KPMFVEKLKNVN-IKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYP 1602

Query: 818  RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA---ARSTVTADLGI 874
            +I      G  +L I    ++D+  YT  A+NK G   +   + V    A       L I
Sbjct: 1603 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1662

Query: 875  PE---QRRYI---EKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
            P    + + I   E                     E  QKP FK  +   + +K  G AH
Sbjct: 1663 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAH 1721

Query: 929  FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
            FE RL PIGD T+ VEWL DG+P+EA++R+     FGY +L        D+G  TCRA N
Sbjct: 1722 FECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1781

Query: 989  AIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKR-----TEEEVKITQKP 1043
              G   TSA L +  +K ++ ESQ P G + +Q +E+  R +          + K  QKP
Sbjct: 1782 KYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKP 1841

Query: 1044 RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVAL 1103
              +       +++EG++A F  RV         V WY NG+ I  + R +  +D G   L
Sbjct: 1842 DIV-LYPEPVRVLEGETARFRCRVTGYPQ--PKVNWYLNGQLIRKSKRFRVRYD-GIHYL 1897

Query: 1104 DIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFV 1163
            DI   ++ D+G   V A N  G  +    + ++ R   D  S+ R   E           
Sbjct: 1898 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE--DFRSVLRRAPEP---------- 1945

Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223
             P + + E  K +   VQ +  P   +E K +    R E +    +  E      S  + 
Sbjct: 1946 RPEFHVHEPGKLQ-FEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE------SEELR 1998

Query: 1224 SRFKTYYDFGFV-ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
            S+FK   + G+  A+  +   S    E     +             ++  +  +T+ + +
Sbjct: 1999 SKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-------ELLHWTKELTEEEKK 2051

Query: 1283 QAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTM 1342
               E+ ++     +  K   E    M+AP+    + +    +G++ H   R++ VG    
Sbjct: 2052 ALAEEGKITIPTFKPDK--IELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRVVGKPDP 2107

Query: 1343 RVEWFCNGKPIKTGHRFRPAYEFDYVA-LDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
              EW+ NG  I+   R    +  D V  L +  V  EDS     +A N  GE  +S A  
Sbjct: 2108 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE-TSSHAFL 2166

Query: 1402 VIAKKDLILESQ 1413
            ++  K LI  +Q
Sbjct: 2167 LVQAKQLITFTQ 2178



 Score =  152 bits (368), Expect = 3e-35
 Identities = 167/695 (24%), Positives = 296/695 (42%), Gaps = 69/695 (9%)

Query: 1939 KESIIRDSQH---ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPV 1995
            +E +I++ ++   ++ LE++  LE+D   K AV        +  F   IKN  + EG  V
Sbjct: 1251 EERLIKEIEYRIIKTTLEEL--LEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGV 1308

Query: 1996 HLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCKA 2054
                 ++    P  ++ WY +G+ ++ G R++  +   G  +L I     ED G Y   A
Sbjct: 1309 TFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA 1366

Query: 2055 TNAVGEAVTTSSVKVDAKSGL----YLDTLDEQRLKKIQELEKYERPK-PIEEEQPGQRP 2109
            +N  G A+ +  + V+  + L    Y+ TL+   + +I+ L      + PI        P
Sbjct: 1367 SNIKGNAICSGKLYVEPAAPLGAPTYIPTLEP--VSRIRSLSPRSVSRSPIRMSPARMSP 1424

Query: 2110 VFLT-ALTSLENLKEGDRAHF--ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
              ++ A  S   +  G R     E ++E +  P   +       K   G   R   D   
Sbjct: 1425 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV--SFKCLEGQTAR--FDLKV 1480

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLE 2224
            V   +  T+    G  +      + +  +   +K  G +++I+    P+  G   +    
Sbjct: 1481 VGRPMPETFWFHDGQQI------VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQN 1534

Query: 2225 AQGHST-----RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
              G S+      +E  E ++ P  FV +L+   ++ EG  +  E +V    +PN  I + 
Sbjct: 1535 RAGRSSISVILTVEAVEHQVKP-MFVEKLKNV-NIKEG--SQLEMKVRATGNPNPDIVWL 1590

Query: 2280 HNGKAL--QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             N   +      +  I    G  +L I   V +D+  Y+  AIN  G  T+   + V  +
Sbjct: 1591 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650

Query: 2338 GSIISESQR---PEGLEKIRELESAE-----------PFKRPEIPEPVTRQRPVFTQPLQ 2383
             +     ++   P G  + +E+ + E            ++  ++ +   +Q+P F + L 
Sbjct: 1651 FAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLT 1710

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++  ++    AHF+CRL P+GDPT+ VEW  + K +E ++R+   ++FGY S+       
Sbjct: 1711 SL-RLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYS 1769

Query: 2444 EDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE--- 2500
             D G+  CRA+N  G               +  E+Q PEG K +Q++E+  ER + E   
Sbjct: 1770 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEE-LERMAHEGAL 1828

Query: 2501 -----PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555
                   +E +KP    +   P  + EG+ A +  RV   G P  +  WY+NG  ++   
Sbjct: 1829 TGVTTDQKEKQKPDIV-LYPEPVRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSK 1885

Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            RFR  +D G   LDI    + D G     A N  G
Sbjct: 1886 RFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1919



 Score =  149 bits (362), Expect = 2e-34
 Identities = 109/429 (25%), Positives = 176/429 (41%), Gaps = 30/429 (6%)

Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
            + T   E  + A T    +E  VK  +PP F ++++P  V ++     E E  G P   +
Sbjct: 5856 SGTYVCEARNDAGTASCSIELKVK--EPPTFIRELKPVEVVKYSDVELECEVTGTPPFEV 5913

Query: 4443 KWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
             W + N  I++S  + +    +   L I +    D+  +  +  N GG+  CS  + ++E
Sbjct: 5914 TWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE 5973

Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                      PPSF    +N            + V G+ PI + WLK+ + +  D    I
Sbjct: 5974 ----------PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYI 6023

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
               D   TL I       SG+Y C A N +G  RC A  +V  PA               
Sbjct: 6024 SFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPA--------------- 6068

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             +I+E  K   V E   +   C + G P   V+W K  K I PS+YF MS   +  + RI
Sbjct: 6069 -QIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRI 6127

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                 +D G Y     N  G  +  A L+V   +   +        D V+  G     + 
Sbjct: 6128 QSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVL--GSSIHMEC 6185

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            +++  +  + QW ++G  I  +  ++++    +  L + N   EDT  +TC+ +  AG  
Sbjct: 6186 KVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDD 6245

Query: 4803 ETSAKLVVK 4811
              S  L VK
Sbjct: 6246 ACSGILTVK 6254



 Score =  148 bits (359), Expect = 4e-34
 Identities = 103/409 (25%), Positives = 173/409 (42%), Gaps = 32/409 (7%)

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
            P+   +PP F +K  P  V       F     G P   + W++ +  +       +    
Sbjct: 8695 PLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLED 8754

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523
            + + L +  V    S  +  +  N  G A C+ +L ++           P  F     + 
Sbjct: 8755 SVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK----------APAKFVKRLNDY 8804

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            ++  G+ + L+   TGT PI V W KNG  V P  R  I   + +  L I  +  +D+G+
Sbjct: 8805 SIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQ 8864

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C   N++G+  C A+ ++                  PP  ++ L+   V+ G +    
Sbjct: 8865 YNCYIENASGKDSCSAQILIL----------------EPPYFVKQLEPVKVSVGDSASLQ 8908

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C++ G P   V WYKGD  ++P+  ++M    +  TL  ++    D G+Y C A NS G 
Sbjct: 8909 CQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGE 8968

Query: 4704 VTVAAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            V+ +  L V    Q   LP      LRD+    G P  F   I+     ++ W ++G  +
Sbjct: 8969 VSASTFLTV----QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPL 9024

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             ++P+ Q     N A L I  T     G ++C AT   G   +SA+L++
Sbjct: 9025 KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 9073



 Score =  147 bits (356), Expect = 1e-33
 Identities = 112/386 (29%), Positives = 180/386 (46%), Gaps = 22/386 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGH-RYRTFHDFGI 3339
            P F+ ++++V  + EG     + R     +PD  + W  N   + PH + + R     G 
Sbjct: 1556 PMFVEKLKNVN-IKEGSQLEMKVRATGNPNPD--IVWLKNSDIIVPHKYPKIRIEGTKGE 1612

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDST--KANLKCTSKE-----NLILDSQLPRGMEG 3392
              L I     ++S  Y   A NK GRD+T  K N++    E      LI+     R  E 
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 3393 GLEKLQTLEDSMVRRK---DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
               +L+ L     + +       ++EK + P F   L+++   R G  AHFE RLTP  D
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGP-AHFECRLTPIGD 1731

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P + VEW  +GK L+A +R R   +FG+  L+    Y  DSG   CRA N YG   T+A+
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791

Query: 3510 MKVQGKRNIILESQLPKGMEGTIDKIAALE--GYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
            + V+ +++++ ESQLP+G +G + +I  LE   + G +  +T + +    P+    P  +
Sbjct: 1792 LIVKDEKSLVEESQLPEGRKG-LQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1850

Query: 3568 ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDA 3627
             + E  +A F CR+        +V W+ NG+ +    R +   D G   L+I      D 
Sbjct: 1851 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1907

Query: 3628 GLYTCKATNRHGEATVSCKLQVKGRQ 3653
            G     A N  G      KL+++ R+
Sbjct: 1908 GEVKVTAENPEGVIEHKVKLEIQQRE 1933



 Score =  146 bits (354), Expect = 2e-33
 Identities = 76/204 (37%), Positives = 109/204 (53%), Gaps = 4/204 (1%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP      Q V V SG+  R    ++G     + W K  + +    + K L +   YTLL
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            ++EA+P+D+  Y C A N  G A   A   V +P   +   P  +    PP II PL+D 
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP---EVVSPDQEMPVYPPAIITPLQDT 3354

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            + +EGQ   F C++ G  L  V WY  DK IKPS++F+M++  D Y L I+EA+PEDEG 
Sbjct: 3355 VTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 3413

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPD 4716
            Y  VA N+ G+V+  A L +  P+
Sbjct: 3414 YTFVASNAVGQVSSTANLSLEAPE 3437



 Score =  146 bits (353), Expect = 2e-33
 Identities = 104/403 (25%), Positives = 173/403 (42%), Gaps = 28/403 (6%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP F K+ +P  V   +   F     G P   + W+R    +       I+   T + L
Sbjct: 6818 EPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAEL 6877

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             +  + +  S  +  V  N  G A C+  L V+E          P +F     + +V  G
Sbjct: 6878 ELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE----------PAAFLKRLSDHSVEPG 6927

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L++  TGT PI V W K+G  +    +  I+  + T  L IL +  +D+G+Y C  
Sbjct: 6928 KSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEI 6987

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG   C A     L +T + P   T+        +EPL+    A G ++   C++ G
Sbjct: 6988 ENEAGRDVCGA-----LVSTLEPPYFVTE--------LEPLE---AAVGDSVSLQCQVAG 7031

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P  TV WYKGD  ++P+  ++   T +  TL  ++    D G+Y C A NS G  +   
Sbjct: 7032 TPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT 7091

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
              ++ +     +      L+DI    G P     ++       + W R+G L+ +  + Q
Sbjct: 7092 VFRIQERQLPPSF--ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQ 7149

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                 N A L I  T    +G ++C A+   G   +SA+L  +
Sbjct: 7150 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 7192



 Score =  144 bits (348), Expect = 9e-33
 Identities = 107/405 (26%), Positives = 171/405 (42%), Gaps = 31/405 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDG-EPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            PP F +K++           FE   +G EPL  + WY++   +K+  + Q       + L
Sbjct: 8042 PPFFARKLKDVHETLGFPVAFECRINGSEPLQ-VSWYKDGVLLKDDANLQTSFVHNVATL 8100

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I Q        +   A N  GTA  SA L++ E         VPP F L   +V++  G
Sbjct: 8101 QILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE-------VPPFFDLKPVSVDLALG 8153

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            +       VTGT PI + W K+ ++++P    K+   + T TL +L+    D+G+Y C A
Sbjct: 8154 ESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYA 8213

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIVAEGQAIEFSCKIV 4647
             N AG+  C A   V                  PP  I+ L+  +IV + +   + CKI 
Sbjct: 8214 SNIAGKDSCSAHLGVQ----------------EPPRFIKKLEPSRIVKQDEFTRYECKIG 8257

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P   V WYK +  I+ S  F+MS       L +     ED GDY C A+N+AG  + +
Sbjct: 8258 GSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSS 8317

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              LKV +P      P       I   +G     + ++       + W ++   +     +
Sbjct: 8318 TSLKVKEPPIFRKKP-----HPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKY 8372

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +++ E     + I N    D G + C+AT   G       + +K+
Sbjct: 8373 KIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA 8417



 Score =  142 bits (344), Expect = 3e-32
 Identities = 113/391 (28%), Positives = 184/391 (47%), Gaps = 33/391 (8%)

Query: 1836 VEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY- 1893
            VE   +Q  P F+ +L     + EG  +  E ++    +PN  + W  N  ++   H+Y 
Sbjct: 1547 VEAVEHQVKPMFVEKLKN-VNIKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVP-HKYP 1602

Query: 1894 --RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ--------SKESII 1943
              R     G AAL I +   +DS  YT  AIN  G+  +  ++NV+         ++ II
Sbjct: 1603 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1662

Query: 1944 RDSQHESA------LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHL 1997
                + +       LE +       +++     D    +KP F K + +  +    P H 
Sbjct: 1663 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHF 1722

Query: 1998 EATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNA 2057
            E  LTP+ DPTM VEW  +G+P++  +R +   +FGY +LD   AY+ D+G   C+ATN 
Sbjct: 1723 ECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNK 1782

Query: 2058 VGEAVTTSSVKV-DAKSGLYLDTLDEQR--LKKIQELEKYERPKPI----EEEQPGQRPV 2110
             G   T++++ V D KS +    L E R  L++I+ELE+      +     +++  Q+P 
Sbjct: 1783 YGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPD 1842

Query: 2111 FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALD 2170
             +     +  L EG+ A F CRV     P   ++W+ NGQ IR   R+R  +D G   LD
Sbjct: 1843 IVLYPEPVRVL-EGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLD 1898

Query: 2171 ILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            I+   + D+G     A N  G   +   L++
Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929



 Score =  142 bits (343), Expect = 4e-32
 Identities = 96/404 (23%), Positives = 163/404 (40%), Gaps = 31/404 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP FT+K++            E +  G P   + W+ E   I +   +Q         L 
Sbjct: 8608 PPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALT 8667

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  +   DS  +  +A N  G+ +CSA L V E          PPSF      ++V +G 
Sbjct: 8668 VNMLEESDSGDYTCIATNMAGSDECSAPLTVRE----------PPSFVQKPDPMDVLTGT 8717

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V   + V GT P  V W K   ++ P  R  +  ED    L + +     SG+Y C+  
Sbjct: 8718 NVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVS 8777

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+A C     +  PA                + ++ L D  + +G+ +       G 
Sbjct: 8778 NEAGKASCTTHLYIKAPA----------------KFVKRLNDYSIEKGKPLILEGTFTGT 8821

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P  +V W K    + PS+   ++ T     L I  +  ED G Y C   N++G+ + +A+
Sbjct: 8822 PPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQ 8881

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            + + +P        +  L  + V  G  A  + Q+    +  + W +    +  T  ++M
Sbjct: 8882 ILILEPPYF-----VKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKM 8936

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                N A L+       D+G + C+A  + G+V  S  L V+ +
Sbjct: 8937 HFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 8980



 Score =  140 bits (338), Expect = 1e-31
 Identities = 101/395 (25%), Positives = 173/395 (43%), Gaps = 36/395 (9%)

Query: 4409 KPPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP F KK+ P  +    E AR   +  G P+  + W++ N  +  S   +++  ++++I
Sbjct: 4662 EPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 4721

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I  V VEDS  ++  A N  G+  CS  +V++E          PPSF  T +  ++  
Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE----------PPSFIKTLEPADIVR 4771

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G    L  +V+GT P ++ W K+ K+++   + ++  +     L I      D G+YECV
Sbjct: 4772 GTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECV 4831

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              N  G+  C A                T     PP  ++ + D I   GQ +     + 
Sbjct: 4832 VANEVGKCGCMA----------------THLLKEPPTFVKKVDDLIALGGQTVTLQAAVR 4875

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G    +V W KG ++I+     +MS +     L I +      G Y C+A N AG  T  
Sbjct: 4876 GSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSV 4935

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI--TSKIKPTIQWLREGALIPETP 4765
             +L V +P +      L     I V  G PA  +  +  T ++KP  +W ++G  +  + 
Sbjct: 4936 GELIVKEPAKIIERAEL-----IQVTAGDPATLEYTVAGTPELKP--KWYKDGRPLVASK 4988

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +++  + N A L   +    D+G +T   +   G
Sbjct: 4989 KYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVG 5023



 Score =  139 bits (337), Expect = 2e-31
 Identities = 118/441 (26%), Positives = 191/441 (43%), Gaps = 29/441 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN--RLTTMHDFGYV 1768
            P+F   +K++ + E   +  E ++   G+P   + WL+N   I      ++      G  
Sbjct: 1556 PMFVEKLKNVNIKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1613

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK-ASLQLESQ----------HESA 1817
            AL +     +DS  YT  AIN+ G   T   + V+ + A  + E +           E A
Sbjct: 1614 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1673

Query: 1818 LQKIQQLE---DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874
              +++ L       +++  +  +    Q P F  +L    +L     AH+ECR+ P  DP
Sbjct: 1674 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPIGDP 1732

Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934
             M VEW  +GK L++ +R R  N+FG+ +LD    Y  DSG  TC+A N  G   +S  L
Sbjct: 1733 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1792

Query: 1935 NVQSKESIIRDSQHESALEKIQYLEDDSRYKR-----AVQDDSFVVEKPQFGKPIKNAEV 1989
             V+ ++S++ +SQ     + +Q +E+  R         V  D    +KP      +   V
Sbjct: 1793 IVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1852

Query: 1990 TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGT 2049
             EG        +T    P  +V WY NG+ +++  RF+  YD G   LDI+   + DTG 
Sbjct: 1853 LEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGE 1909

Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRP 2109
                A N   E V    VK++ +      ++  +  +   E   +E  K   E Q   RP
Sbjct: 1910 VKVTAENP--EGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRP 1967

Query: 2110 VFLTALTSLENLKEGDRAHFE 2130
            V  T    +  LK  +R   E
Sbjct: 1968 VDTTETKEVVKLKRAERITHE 1988



 Score =  136 bits (330), Expect = 1e-30
 Identities = 116/410 (28%), Positives = 186/410 (45%), Gaps = 44/410 (10%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F K ++  +V E ++A FE E   EP   ++W +++  ++ +   +I        L+I  
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPS 3118

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              + D+  +  VA     TAK    L VE +  + R            + V V   Q   
Sbjct: 3119 TRMSDAGKYTVVAGGNVSTAK----LFVEGRDVRIRS---------IKKEVQVIEKQRAV 3165

Query: 4533 LDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            ++ +V     +D +W K+G ++  Q   R+K + E   + + I E    D+G+Y  VA  
Sbjct: 3166 VEFEVN-EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA-- 3222

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
              G  R      V+ P               PP++++ L+   V  G+   F   I G+P
Sbjct: 3223 --GRNRSSVTLYVNAPE--------------PPQVLQELQPVTVQSGKPARFCAVISGRP 3266

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P + WYK ++L+      +      EYTL + EAFPED   Y C A N  G  T +A L
Sbjct: 3267 QPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASL 3326

Query: 4711 -----KVTQPDQADNL--PA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                 +V  PDQ   +  PA +TPL+D V  EGQPA+F+ ++ S     + W  +   I 
Sbjct: 3327 SVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIK 3385

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  F+M    +   L I   Y ED GT+T  A+ A GQV ++A L +++
Sbjct: 3386 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435



 Score =  136 bits (330), Expect = 1e-30
 Identities = 98/403 (24%), Positives = 169/403 (41%), Gaps = 29/403 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP F ++++                +G     + WYR+   +++  + Q       + L 
Sbjct: 7101 PPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLK 7160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q  +  S  ++  A N  GTA  SA L   E ++        P F +   +++V +G+
Sbjct: 7161 ILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKS-------PFFDIKPVSIDVIAGE 7213

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
                +  VTG +P+ + W K+ K+++P     I     T  L IL+    DSG+Y C A 
Sbjct: 7214 SADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQAT 7273

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIVAEGQAIEFSCKIVG 4648
            N  G+  C A+  V                  PP+ ++ L+  K+  +G++I+  CKI G
Sbjct: 7274 NDVGKDMCSAQLSVK----------------EPPKFVKKLEASKVAKQGESIQLECKISG 7317

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P   V W++ D  +  S  + MS       L I+EA  ED GDY C A+N  G  + + 
Sbjct: 7318 SPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCST 7377

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V  P      P+      +   +G     + +I+      + W+++   +  +  F+
Sbjct: 7378 ALTVKAPPVFTQKPS-----PVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFK 7432

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +  +  L I N    D G + C+AT   G    S  +  K
Sbjct: 7433 ITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFK 7475



 Score =  136 bits (329), Expect = 2e-30
 Identities = 100/408 (24%), Positives = 176/408 (43%), Gaps = 33/408 (8%)

Query: 4409 KPPIFTKKMQPCRVFEHEQ-ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP F KK++P R+ + ++  R+E +  G P   + WY++   I+ S  F++    + ++
Sbjct: 8230 EPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAV 8289

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L +  + VEDS  +   A N  G+A  S +L V+E          PP F      +    
Sbjct: 8290 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE----------PPIFRKKPHPIETLK 8339

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G  V L+ ++ GT P  V W K+ ++++   + KI+ E+   ++ IL     D G+Y+C 
Sbjct: 8340 GADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCK 8399

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N  G       CV S+            A  APP  ++ L D     G+ ++    I 
Sbjct: 8400 ATNDVG----SDTCVGSI------------ALKAPPRFVKKLSDISTVVGKEVQLQTTIE 8443

Query: 4648 GKPLPTVQWYKG-DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G    +V W+K   ++++ S    +S + +  TL+ S   P + G Y C   N AG    
Sbjct: 8444 GAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQEC 8503

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
             A L V +P      P       I V  G     +  +    + + +W ++G  +     
Sbjct: 8504 FATLSVLEPATIVEKP-----ESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNK 8558

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            +++      + L I N    D+G ++       G+   +A L V  +T
Sbjct: 8559 YKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT 8606



 Score =  134 bits (324), Expect = 7e-30
 Identities = 128/502 (25%), Positives = 219/502 (43%), Gaps = 32/502 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++  K     HFEC + P  DPT+ +EW  + KPL +  R +  ++F Y SLD 
Sbjct: 1705 FKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDY 1764

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE-AR 2894
               Y  DSGI TC+ATN  G+  TS +L    +K++  ++Q P+G+ GL+ +E+ E  A 
Sbjct: 1765 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1824

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
                   +    E  KP+ I+      +++EG+      +V     P  K+ WY NG+++
Sbjct: 1825 EGALTGVTTDQKEKQKPD-IVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQLI 1881

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN---LIE 3011
             +  RF++  D G   LD+VD    D+G     A N  G       +    +++   ++ 
Sbjct: 1882 RKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLR 1940

Query: 3012 RTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQ-IAHY-- 3068
            R   P+    + +   L+  ++K           RP + TT  K++V +   + I H   
Sbjct: 1941 RAPEPRPEFHVHEPGKLQFEVQK---------VDRPVD-TTETKEVVKLKRAERITHEKV 1990

Query: 3069 --EASLIPTGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMV--VLEILGTKTTDSGTYSC 3123
              E+  + +  +    E +Y   T +E   R +      ++    + L   T +      
Sbjct: 1991 PEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEK 2050

Query: 3124 RATNKWGQAEI-SVKLECVDKSKGQK-PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181
            +A  + G+  I + K + ++ S   + P+    IQ+ + +  G  AHF   VV   DP+ 
Sbjct: 2051 KALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC 2109

Query: 3182 KIEWYHNGQPMRHSTRIKTV-SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
              EWY NG  +  S RI     +     L I      DS   + +A N  GE  + A + 
Sbjct: 2110 --EWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLL 2167

Query: 3241 CYGKGGVYLESLQPDSLAKIRE 3262
               K  +       D +AK ++
Sbjct: 2168 VQAKQLITFTQELQDVVAKEKD 2189



 Score =  133 bits (322), Expect = 1e-29
 Identities = 139/532 (26%), Positives = 224/532 (42%), Gaps = 76/532 (14%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P     ++ + V   + A F A  +  G P+ ++ W +    +    +   +HD    
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCA--VISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L +    PED+  YTC A N+ G A TS        ASL +E     +           
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGVATTS--------ASLSVEVPEVVS----------- 3335

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
                  D E+ V   P  IT L   T  SEGQ A ++CR+      +++V WY   K ++
Sbjct: 3336 -----PDQEMPV-YPPAIITPLQD-TVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIK 3385

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS-Q 1947
                +R +       L+I   Y ED G YT  A N +GQ  S+  L++++ ESI+ +  +
Sbjct: 3386 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIE 3445

Query: 1948 HESALEKIQY------LEDDSRYKRAVQ-----------------DDSFVVEK----PQF 1980
             E  +E  ++       E++  +   +Q                    F  EK    P F
Sbjct: 3446 QEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIF 3505

Query: 1981 GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDIL 2040
             K + NA+++ G    L  T+  +  P  +++W+ NG  +     +K  +D    +L IL
Sbjct: 3506 IKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSLIIL 3563

Query: 2041 YAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPI 2100
            +   ED G Y C A+N  G+ + ++ +K+++K   + DT  E  + K   LEK   P P 
Sbjct: 3564 FTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--SLEKLGGPCP- 3620

Query: 2101 EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT 2160
                    P FL  L  +    +G  A FE  V  + +P  T+ WF   +++     Y  
Sbjct: 3621 --------PHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTI 3669

Query: 2161 THD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
             H+  G     +     EDSG Y+CKA N LGE+     L V      + DT
Sbjct: 3670 IHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 3721



 Score =  133 bits (322), Expect = 1e-29
 Identities = 92/321 (28%), Positives = 155/321 (48%), Gaps = 24/321 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVE--FDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            PP FTK++    V E E   F++E    G     + WY+ N  I+ + + +I   +   +
Sbjct: 9175 PPSFTKRLSET-VEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 9233

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L +R+  + D+ ++     N  G+A C++++V++E ++       PP F      V V+ 
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKK-------PPVFDQHLTPVTVSE 9286

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+ V+L   V G++PI + WLK G++++P  R       GT  L + +    DSG Y C 
Sbjct: 9287 GEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCK 9346

Query: 4588 AINSAGEARCDAECVVSLPATKDKPK--PQTKAANAPPEII---EPLKDKIVAEGQAIEF 4642
            A N AG     ++  +     KDKP   P TK A     +    EP   ++V +  A  F
Sbjct: 9347 ASNVAGSDTTKSKVTI-----KDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTAT-F 9400

Query: 4643 SCKIVGKPLPTVQWYKGD--KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
              K+ G P+P V+W KG   +L +  + F + +  DE  L I +    D G Y+CVA+N 
Sbjct: 9401 IAKVGGDPIPNVKWTKGKWRQLNQGGRVF-IHQKGDEAKLEIRDTTKTDSGLYRCVAFNE 9459

Query: 4701 AGRVTVAAKLKVTQPDQADNL 4721
             G +     L+V +  + + +
Sbjct: 9460 HGEIESNVNLQVDERKKQEKI 9480



 Score =  132 bits (319), Expect = 3e-29
 Identities = 101/403 (25%), Positives = 163/403 (40%), Gaps = 27/403 (6%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P   T++     V + + A  +V+F G      KW+++   +     ++I    T SIL
Sbjct: 5504 EPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSIL 5563

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I     +DS  +    +N  G + C A + V +        I+PPSFT   + ++   G
Sbjct: 5564 KIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDL-------IIPPSFTKKLKKMDSIKG 5616

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+  V G+ PI + W K+ +++    + K    D T  L I +    DSG Y C A
Sbjct: 5617 SFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSA 5676

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG  +C     V                  PP  +E  + + V     ++    + G
Sbjct: 5677 TNKAGHNQCSGHLTV----------------KEPPYFVEKPQSQDVNPNTRVQLKALVGG 5720

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
                T++W+K +K +       + +     +L +  A   D G Y C   N  G  T  A
Sbjct: 5721 TAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKA 5780

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P Q    P  +P+  +V+  GQ   F+ QIT   K  + W  +G  I       
Sbjct: 5781 TLFVKEPPQFIKKP--SPV--LVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHG 5836

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +      A   I     E++GT+ C A   AG    S +L VK
Sbjct: 5837 ISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 5879



 Score =  132 bits (318), Expect = 4e-29
 Identities = 100/408 (24%), Positives = 172/408 (42%), Gaps = 32/408 (7%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V  + PP F  + +    F  + A+F     G P+    W ++   +  SP+++I     
Sbjct: 4472 VTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAEN 4531

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
            K IL +  + ++D  V++  A N+ G   C A L++ +K          P F    + V 
Sbjct: 4532 KHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK----------PHFIKELEPVQ 4581

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
                + V L+ +V   + + V W K+G+K+ P    KI  ED   TL I  A  +DSG Y
Sbjct: 4582 SAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTY 4641

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK-IVAEGQAIEFS 4643
             C A N AG + C A                T     PP  ++ +    ++  G++    
Sbjct: 4642 VCTASNEAGSSSCSA----------------TVTVREPPSFVKKVDPSYLMLPGESARLH 4685

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            CK+ G P+  V W+K +K +  S   +M     E  L I++   ED G Y C A N  G 
Sbjct: 4686 CKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGS 4745

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             + + ++ + +P     +  L P  DIV   G  A  + +++      I W ++   I  
Sbjct: 4746 DSCSTEIVIKEPPSF--IKTLEP-ADIV--RGTNALLQCEVSGTGPFEISWFKDKKQIRS 4800

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +++  + +   L I +    D G + C      G+    A  ++K
Sbjct: 4801 SKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLK 4848



 Score =  129 bits (311), Expect = 3e-28
 Identities = 107/421 (25%), Positives = 176/421 (41%), Gaps = 29/421 (6%)

Query: 4391 EHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP 4450
            E++A +Q  V E  VK  +P    ++ +  +V   + A  E    G P    KWY++  P
Sbjct: 4926 ENEAGSQTSVGELIVK--EPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 4983

Query: 4451 IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG 4510
            +  S  ++I   +  + L      + DS  +     N  G++ C     V ++       
Sbjct: 4984 LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRD------ 5037

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             + P FT   +NV+       RLD K+ G+ P+ V W K+GK++    R +I   +GT +
Sbjct: 5038 -IAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L I+     D+G + C A NS G        +V                  PP  +    
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV----------------QEPPSFVTKPG 5140

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
             K V  G A+       G    T++W+KG+K +       +++ A E +L +      D 
Sbjct: 5141 SKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDS 5200

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G Y C   N AG V  +A L V +P  A  +  L P +  ++ +G   Q   ++T     
Sbjct: 5201 GTYTCKVSNVAGGVECSANLFVKEP--ATFVEKLEPSQ--LLKKGDATQLACKVTGTPPI 5256

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             I W      I E+   +M    + AVL + +   ED+G + C A   AG    S+ ++V
Sbjct: 5257 KITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV 5316

Query: 4811 K 4811
            K
Sbjct: 5317 K 5317



 Score =  129 bits (311), Expect = 3e-28
 Identities = 107/405 (26%), Positives = 164/405 (40%), Gaps = 29/405 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P  F K++    V        E  + G P   + W ++ + I  S    I      +IL
Sbjct: 7852 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTIL 7911

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +  +ED A ++ + EN  G   C A + V E          PP F    ++V    G
Sbjct: 7912 EILESTIEDYAQYSCLIENEAGQDICEALVSVLE----------PPYFIEPLEHVEAVIG 7961

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            +   L  KV GT  I + W K   K++     K+  ++   +L+I +    D G+Y C A
Sbjct: 7962 EPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKA 8021

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             NS G     A  V+             K    PP     LKD     G  + F C+I G
Sbjct: 8022 DNSVGAVASSAVLVI-------------KERKLPPFFARKLKDVHETLGFPVAFECRING 8068

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
                 V WYK   L+K     Q S   +  TL+I +      G Y C A N  G  + +A
Sbjct: 8069 SEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSA 8128

Query: 4709 KLKVTQPDQADNLPALTPLRDIVV--YEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
            KL +++ +    +P    L+ + V    G+   FK  +T      I W ++   I    +
Sbjct: 8129 KLILSEHE----VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGN 8184

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            ++M    N A L +    + D G +TC A+  AG+   SA L V+
Sbjct: 8185 YKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQ 8229



 Score =  128 bits (310), Expect = 4e-28
 Identities = 102/404 (25%), Positives = 172/404 (42%), Gaps = 32/404 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP F +      V       F     G P   +KW++ +  +       I      + L
Sbjct: 7759 EPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTEL 7818

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             + +V   +S  ++ +  N  G+A C+ +L V+E          P +F     + +V +G
Sbjct: 7819 ELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKE----------PATFVKRLADFSVETG 7868

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+   TGT PI V W+K+   +    R  I   + +  L ILE+  +D  +Y C+ 
Sbjct: 7869 SPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLI 7928

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG+  C+A  +VS+                PP  IEPL+      G+     CK+ G
Sbjct: 7929 ENEAGQDICEA--LVSV--------------LEPPYFIEPLEHVEAVIGEPATLQCKVDG 7972

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P   + WYK    ++ +  ++M    +  +L I++    D G+Y C A NS G V  +A
Sbjct: 7973 TPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSA 8032

Query: 4709 KLKVTQPDQADNLPAL--TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
             L + +      LP      L+D+    G P  F+ +I       + W ++G L+ +  +
Sbjct: 8033 VLVIKE----RKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDAN 8088

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             Q     N A L I  T +   G + C A+   G   +SAKL++
Sbjct: 8089 LQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL 8132



 Score =  128 bits (309), Expect = 5e-28
 Identities = 102/387 (26%), Positives = 167/387 (43%), Gaps = 25/387 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF---RFGY 693
            P F+  LK+V   EG ++  E ++   G+P   I WLKN   I    ++  I      G 
Sbjct: 1556 PMFVEKLKNVNIKEGSQL--EMKVRATGNPNPDIVWLKNSDII-VPHKYPKIRIEGTKGE 1612

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT--------------PRATIERTSQ 739
             +L + S   QDS  YT  A++  G   T+  ++V               PR T      
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 740  HPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSD 799
                L+ +       +++  +  +++  Q+P F + L  L  L+    AHFE +LTP+ D
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPIGD 1731

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PTM VEW  DG+P+ A++R+  I  FGY SL+     + D+G  T RA NK G   ++A+
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791

Query: 860  IRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQI 919
            + V    ++  +  +PE R+ +++                    +  QKP+      + +
Sbjct: 1792 LIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEPV 1850

Query: 920  SIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDA 979
             + EG  A F  R+   G    +V W  +G+ +  S R    ++ G   L I     +D 
Sbjct: 1851 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1907

Query: 980  GHYTCRAYNAIGQATTSANLTIVTKKD 1006
            G     A N  G       L I  ++D
Sbjct: 1908 GEVKVTAENPEGVIEHKVKLEIQQRED 1934



 Score =  128 bits (308), Expect = 6e-28
 Identities = 99/410 (24%), Positives = 170/410 (41%), Gaps = 32/410 (7%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
            G +   +PP F +K Q   V  + + + +    G     IKW+++N  + +     +   
Sbjct: 5687 GHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKD 5746

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
             T + L +      DS  +     N  GTA   A L V+E          PP F      
Sbjct: 5747 DTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE----------PPQFIKKPSP 5796

Query: 4523 VNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            V V  +GQ    + ++TGT  I V W  +G ++    ++ I   DG  T  I  A  ++S
Sbjct: 5797 VLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENS 5856

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G Y C A N AG A C  E  V                  PP  I  LK   V +   +E
Sbjct: 5857 GTYVCEARNDAGTASCSIELKVK----------------EPPTFIRELKPVEVVKYSDVE 5900

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
              C++ G P   V W K ++ I+ SK + ++     + L I++  P D G+Y+C+  N  
Sbjct: 5901 LECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEG 5960

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            G  + + ++ + +P        +  + +        A F++ +      +I WL++  ++
Sbjct: 5961 GSCSCSTRVALKEPPS-----FIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQIL 6015

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             E  +  +    + A L I +     +G +TC+A   +G     A L+V+
Sbjct: 6016 DEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 6065



 Score =  126 bits (305), Expect = 1e-27
 Identities = 85/307 (27%), Positives = 136/307 (44%), Gaps = 16/307 (5%)

Query: 66   PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            PGEP+ P F       +  +GG+  F  ++ GNP P V W +   PL    +Y + YN+Q
Sbjct: 1076 PGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1135

Query: 126  TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR----- 180
            TG+  L+I      D GEYT   RN++GE   S  +  E              Y+     
Sbjct: 1136 TGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1195

Query: 181  -----HVSETVEHKAYG--TQGYTTEQSRQTQKVAYTNGTDHSSTDD--FKVDTFEYRLL 231
                  V ET     Y    + Y  EQ+   +K+A       +  +D  F + +FE RL+
Sbjct: 1196 FVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1255

Query: 232  REVSFR-ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLS 290
            +E+ +R    T   + E D +    +D S           + +N ++ EG    F  ++S
Sbjct: 1256 KEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMS 1315

Query: 291  GNPRPRVTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            G P P++ W+K+G+R+ +  ++++        +LR+      D G YT  A N  G  + 
Sbjct: 1316 GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAIC 1375

Query: 350  SGYLAVE 356
            SG L VE
Sbjct: 1376 SGKLYVE 1382



 Score =  126 bits (305), Expect = 1e-27
 Identities = 165/633 (26%), Positives = 257/633 (40%), Gaps = 93/633 (14%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            GR     ++ K+ V + E Q A  E  +    +  +   W+ +G  I    + R  Y   
Sbjct: 3144 GRDVRIRSIKKE-VQVIEKQRAVVEFEV---NEDDVDAHWYKDGIEINFQVQERHKYVVE 3199

Query: 3105 MVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
              +  + I  T+ +D+G Y+  A    G+   SV L     +  + P+    +Q +  ++
Sbjct: 3200 RRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV---NAPEPPQVLQELQPVT-VQ 3251

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G+ A F C V+    P  KI WY   Q +    + K + D     L +      D+  Y
Sbjct: 3252 SGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVY 3309

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282
             C A N YG   T A+++                     E+  +    Q+ P      PP
Sbjct: 3310 TCEAKNDYGVATTSASLSV--------------------EVPEVVSPDQEMP----VYPP 3345

Query: 3283 KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
              IT +QD T   EGQ A F+ R   V   DLKV W+   KK+     +R         L
Sbjct: 3346 AIITPLQD-TVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQL 3401

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLI---LDSQLPRGM--------- 3390
            +I   Y E+ G Y  VA+N +G+ S+ ANL   + E+++   ++ ++   M         
Sbjct: 3402 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLS 3461

Query: 3391 --EGGL-----------EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGEN 3437
              E GL           E L+ L +S V       E+E G  P+F   +SN + +  G+ 
Sbjct: 3462 AEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKE-GTGPIFIKEVSNAD-ISMGDV 3519

Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRA 3497
            A     +T    P  K++W++NG  L   + ++   D     L I  T  ED GEY C A
Sbjct: 3520 ATLS--VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMA 3577

Query: 3498 YNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP 3557
             N+YG+ + +A +K+  K     E       E  + K  +LE   G             P
Sbjct: 3578 SNDYGKTICSAYLKINSKG----EGHKDTETESAVAK--SLEKLGGPC-----------P 3620

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI-NDFGFVI 3616
            P F      +  ++   A FE  +  V + +  V WF   K L T      I N  G   
Sbjct: 3621 PHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGT 3678

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              +    + D+GLY CKA N  GE+T + +L V
Sbjct: 3679 FIVNDPQREDSGLYICKAENMLGESTCAAELLV 3711



 Score =  126 bits (304), Expect = 2e-27
 Identities = 98/401 (24%), Positives = 165/401 (41%), Gaps = 28/401 (6%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P+  +K++P  V     A+F  E    P    +W++    I  S    I +    S L I
Sbjct: 4383 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4442

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
             +  V D   +   A N  G+  C+A L V E          PP+F    +++    G+ 
Sbjct: 4443 LRTQVVDCGEYTCKASNEYGSVSCTATLTVTE--------AYPPTFLSRPKSLTTFVGKA 4494

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
             +    VTGT  I+  W K+G  + P    KI + +  + L +     QD G Y C A N
Sbjct: 4495 AKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASN 4554

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
              G   C AE ++      DK           P  I+ L+    A  + +   C++    
Sbjct: 4555 KFGADICQAELIII-----DK-----------PHFIKELEPVQSAINKKVHLECQVDEDR 4598

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
              TV W K  + + P K +++       TL I  A  +D G Y C A N AG  + +A +
Sbjct: 4599 KVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATV 4658

Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMI 4770
             V +P     +  + P    ++  G+ A+   ++       + W +    + E+   +M 
Sbjct: 4659 TVREPPSF--VKKVDP--SYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMY 4714

Query: 4771 HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               + A+L I +   ED+G+++C A    G    S ++V+K
Sbjct: 4715 FVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK 4755



 Score =  125 bits (302), Expect = 3e-27
 Identities = 93/402 (23%), Positives = 163/402 (40%), Gaps = 32/402 (7%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F K+++P +   +++   E + D +    + W ++   +    D++I      + L I
Sbjct: 4571 PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEI 4630

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ-NVNVTSGQ 4529
                ++DS  +   A N  G++ CSA + V E          PPSF      +  +  G+
Sbjct: 4631 PLAKLKDSGTYVCTASNEAGSSSCSATVTVRE----------PPSFVKKVDPSYLMLPGE 4680

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
              RL  K+ G+  I V W KN K++      ++   +    L I +   +DSG Y C A+
Sbjct: 4681 SARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAV 4740

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N  G   C  E V+                  PP  I+ L+   +  G      C++ G 
Sbjct: 4741 NDVGSDSCSTEIVIK----------------EPPSFIKTLEPADIVRGTNALLQCEVSGT 4784

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
                + W+K  K I+ SK +++        L I      D G+Y+CV  N  G+    A 
Sbjct: 4785 GPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMAT 4844

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
              + +P        +  + D++   GQ    +  +      ++ W++   +I E    +M
Sbjct: 4845 HLLKEPPTF-----VKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKM 4899

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                  AVL+I +      G +TC A   AG   +  +L+VK
Sbjct: 4900 SFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVK 4941



 Score =  125 bits (302), Expect = 3e-27
 Identities = 108/408 (26%), Positives = 167/408 (40%), Gaps = 35/408 (8%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            +P K P F  K     V   E A FE    G     I W ++N  I+   ++ I      
Sbjct: 7193 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNT 7252

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
              L I +V   DS  +   A N  G   CSA L V+E          PP F    +   V
Sbjct: 7253 PHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE----------PPKFVKKLEASKV 7302

Query: 4526 TS-GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
               G+ ++L+ K++G+  I V W +N  ++    +  +   +    L I EA  +DSG Y
Sbjct: 7303 AKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDY 7362

Query: 4585 ECVAINSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
             C A N  G+A C     V  P     KP P           +  LK      G  +   
Sbjct: 7363 ICEAHNGVGDASCSTALTVKAPPVFTQKPSP-----------VGALK------GSDVILQ 7405

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C+I G P   V W K  K ++ SK F+++    + +L I      D G+Y C A N  G 
Sbjct: 7406 CEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGS 7465

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE-GALIP 4762
             T +  +K  +P +      +  L D     G   + +  +      ++ WL++ G +I 
Sbjct: 7466 DTCSCSVKFKEPPR-----FVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIR 7520

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            E+ + ++    N A L +G+    ++G + C+    AG  E SA L V
Sbjct: 7521 ESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 7568



 Score =  125 bits (301), Expect = 5e-27
 Identities = 101/395 (25%), Positives = 168/395 (42%), Gaps = 32/395 (8%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P    +K +P  V        E    G P    KW+++   +       I   +  + L
Sbjct: 7570 EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASL 7629

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I    + D  +++   +N  G + C+ ++ V ++       IVPPSF    ++VN   G
Sbjct: 7630 KIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDR-------IVPPSFIRKLKDVNAILG 7682

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
              V L+ +V+G+ PI V W ++G ++   P  ++   E   T  L +LE  P D+G Y C
Sbjct: 7683 ASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLE--PSDTGIYTC 7740

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VA N AG   C A   V  P + +    QT      P+ +E      V  G ++ F+  I
Sbjct: 7741 VAANVAGSDECSAVLTVQEPPSFE----QT------PDSVE------VLPGMSLTFTSVI 7784

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G P   V+W+KG + + P +   +S       L + E  P + GDY C+  N AG  + 
Sbjct: 7785 RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASC 7844

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V +P        +  L D  V  G P   +   T     ++ W+++  LI ++  
Sbjct: 7845 TTHLFVKEP-----ATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSER 7899

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              +     + +L I  +  ED   ++C     AGQ
Sbjct: 7900 CSITMTEKSTILEILESTIEDYAQYSCLIENEAGQ 7934



 Score =  124 bits (300), Expect = 6e-27
 Identities = 132/499 (26%), Positives = 213/499 (42%), Gaps = 75/499 (15%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            K+ W+K  Q ++ G + + +HD     L +I+   ED+ +YTC A N  G    S  L+ 
Sbjct: 3269 KISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3328

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
                ++V   Q                        E+    P   T L++    EGQ A 
Sbjct: 3329 E-VPEVVSPDQ------------------------EMPVYPPAIITPLQDTVTSEGQPAR 3363

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656
            F+ R   VS   LKV WY  +K +K    F  T       L+I    PED GTYT  A N
Sbjct: 3364 FQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASN 3420

Query: 1657 ALGE-AVTSGI------AIVHSK------------KSIYLESQHEG------ALPRLNQ- 1690
            A+G+ + T+ +      +I+H +             S +L ++ EG       L ++N+ 
Sbjct: 3421 AVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINET 3480

Query: 1691 LEDTSKYQRHSAQ--DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748
            LE  S+   +S +   E     P+F   + +  ++    A     +I  G PK +++W  
Sbjct: 3481 LELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVI--GIPKPKIQWFF 3538

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
            NGV +  S     + D    +L + +   ED G YTC A N+ G+ + S+ L + SK   
Sbjct: 3539 NGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEG 3598

Query: 1809 QLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRI 1868
              +++ ESA+ K   LE           ++     P F+ +L  P + ++G  A +E  +
Sbjct: 3599 HKDTETESAVAK--SLE-----------KLGGPCPPHFLKELK-PIRCAQGLPAIFEYTV 3644

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
               P P   V W+   K L +   Y    N  G     +     EDSG Y CKA N LG+
Sbjct: 3645 VGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGE 3702

Query: 1928 AVSSIRLNVQSKESIIRDS 1946
            +  +  L V  +++ + D+
Sbjct: 3703 STCAAELLVLLEDTDMTDT 3721



 Score =  124 bits (299), Expect = 8e-27
 Identities = 93/408 (22%), Positives = 177/408 (43%), Gaps = 33/408 (8%)

Query: 4408 SKPPIFTKKMQPCRVFEH-EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS 4466
            ++PP F KK++  ++ +  + +R E +  G P   + W+R    +  S  +++    + +
Sbjct: 6347 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 6406

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
            ++ +  +  EDS  F   A+N  G+  CS  ++V+E          PP F+     V   
Sbjct: 6407 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE----------PPVFSSFPPIVETL 6456

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
                V L+ +++GT P +V W K+ ++++   + KI  ++   ++ IL     D G+Y C
Sbjct: 6457 KNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHC 6516

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
             A N  G   C   C V L                PP  +  L    V  G+  E    I
Sbjct: 6517 KAQNEVGSDTC--VCTVKL--------------KEPPRFVSKLNSLTVVAGEPAELQASI 6560

Query: 4647 VGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             G     VQW K  +++I+ S+  +++   +  TL+ ++A P + G Y C   N  G   
Sbjct: 6561 EGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEE 6620

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
              A L V +P  A  +    P+    V  G+    + ++    + +++W ++G L+  + 
Sbjct: 6621 NMATLMVLEP--AVIVEKAGPM---TVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQ 6675

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              +       + L I +   +D GT+T +     G+   +A + V  +
Sbjct: 6676 KHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDR 6723



 Score =  123 bits (296), Expect = 2e-26
 Identities = 94/405 (23%), Positives = 169/405 (41%), Gaps = 31/405 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P    +K +   V E +    E    G P   +KW ++   I  S  F +   +  +  
Sbjct: 6066 EPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASF 6125

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I+ V  +DS  +    EN  G++ C A L V ++        +PPSFT     ++   G
Sbjct: 6126 RIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQN-------IPPSFTKKLTKMDKVLG 6178

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + ++ KV+G+ PI   W K+GK++    + +++  + + +L +     +D+  Y C  
Sbjct: 6179 SSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKV 6238

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG+  C     V  P               P  +++P + + + +   +EF   + G
Sbjct: 6239 SNVAGDDACSGILTVKEP---------------PSFLVKPGRQQAIPD-STVEFKAILKG 6282

Query: 4649 KPLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             P   ++W+K D +L+   K F +        L +        G Y C   N  G  +  
Sbjct: 6283 TPPFKIKWFKDDVELVSGPKCF-IGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCT 6341

Query: 4708 AKLKVTQPDQ-ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
              L VT+P +    L A       +V  G  ++ + +I    +  + W R    +P +  
Sbjct: 6342 TMLLVTEPPKFVKKLEA-----SKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDK 6396

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            ++M    + AV+ + N   ED+G F C A   AG    S K++VK
Sbjct: 6397 YRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 6441



 Score =  123 bits (296), Expect = 2e-26
 Identities = 151/713 (21%), Positives = 268/713 (37%), Gaps = 57/713 (7%)

Query: 4105 SKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DG 4163
            S+   PP F   P +V +  GE   F C VTG    ++ W  +   I  G  YK+T  + 
Sbjct: 8133 SEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN 8192

Query: 4164 MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQ 4223
                 + K  + D G+                 L V    +  R + K  P         
Sbjct: 8193 TATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGV---QEPPRFIKKLEP--------- 8240

Query: 4224 YQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE 4283
                     +  ++ +  + +  I   PE+K    K+ ETE Q+S K + +      + E
Sbjct: 8241 --------SRIVKQDEFTRYECKIGGSPEIKVLWYKD-ETEIQESSKFRMSFVDSVAVLE 8291

Query: 4284 LENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQ 4343
            + N  V          H  A      TS  V +    R + +  +T +  +  ++ ++  
Sbjct: 8292 MHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQG 8351

Query: 4344 KPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQ--ERVV 4401
             P  P         +E+   K+ +   E          + + +  E + KA         
Sbjct: 8352 TP--PFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTC 8409

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG-EPLPLIKWYRENFPI-KNSPDFQI 4459
             G +    PP F KK+        ++ + +   +G EP+ ++ W+++   I + S +  I
Sbjct: 8410 VGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVV-WFKDKGEIVRESDNIWI 8468

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
                  + L   +V   ++  +    +N  G  +C A L V E          P +    
Sbjct: 8469 SYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE----------PATIVEK 8518

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             +++ VT+G    L+  V GT  +   W K+GK++  D + KI   +    L I+   P 
Sbjct: 8519 PESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPS 8578

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            DSG Y     N  G+  C A   VS     D+          PP     LK+     G +
Sbjct: 8579 DSGVYSFEVQNPVGKDSCTASLQVS-----DR--------TVPPSFTRKLKETNGLSGSS 8625

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            +   CK+ G P  +V W+     I   + +Q + T +   L ++     D GDY C+A N
Sbjct: 8626 VVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATN 8685

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
             AG    +A L V +P      P   P+ D++   G    F + +      ++ W +  +
Sbjct: 8686 MAGSDECSAPLTVREPPSFVQKP--DPM-DVLT--GTNVTFTSIVKGTPPFSVSWFKGSS 8740

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +       +  E + A L + +     +G +TC  +  AG+   +  L +K+
Sbjct: 8741 ELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKA 8793



 Score =  122 bits (294), Expect = 3e-26
 Identities = 128/587 (21%), Positives = 240/587 (40%), Gaps = 53/587 (9%)

Query: 4237 ERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLR 4296
            E+  +  + V+   PELK K +K+ +   Q    R  +  + N +     + V+K+    
Sbjct: 6081 EKDPMTLECVVAGTPELKVKWLKDGK---QIVPSRYFSMSFENNVASFRIQSVMKQD--- 6134

Query: 4297 ESTHQYAIPGDKVTSNTVA------KSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDP 4350
               + + +  D  +S+  A      +++   +   L + ++V    +  +      +P  
Sbjct: 6135 SGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPIS 6194

Query: 4351 SESTVHGKEVHV-AKQKQTQKEVVGDKEITR---KITSTETTEIEHKAQTQERVVEGPVK 4406
            ++    GKE+   AK +    E     E+     + T+  T ++ + A   +    G + 
Sbjct: 6195 AQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAG--DDACSGILT 6252

Query: 4407 PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS 4466
              +PP F  K    +        F+    G P   IKW++++  + + P   I    + S
Sbjct: 6253 VKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTS 6312

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVN 4524
             L +  V    +  +     N  G+  C+  L+V E          PP F   L A  + 
Sbjct: 6313 FLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE----------PPKFVKKLEASKI- 6361

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V +G   RL+ K+ G+  I V W +N  ++    + ++   D    + +     +DSG +
Sbjct: 6362 VKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDF 6421

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C A N AG   C  + +V     K+ P       ++ P I+E LK+   AE   +   C
Sbjct: 6422 ICEAQNPAGSTSCSTKVIV-----KEPP-----VFSSFPPIVETLKN---AE---VSLEC 6465

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            ++ G P   V WYK  + ++ SK ++++      ++ I      D G+Y C A N  G  
Sbjct: 6466 ELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSD 6525

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE-GALIPE 4763
            T    +K+ +P +      ++ L  + V  G+PA+ +  I       +QWL+E   +I E
Sbjct: 6526 TCVCTVKLKEPPR-----FVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRE 6580

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + + ++    N A L        + G + C+     G  E  A L+V
Sbjct: 6581 SENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMV 6627



 Score =  122 bits (293), Expect = 4e-26
 Identities = 135/561 (24%), Positives = 226/561 (40%), Gaps = 79/561 (14%)

Query: 3643 VSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETL---HKREEITIEDEKPNPPRFTV 3699
            +    QV+ R   ++E ++   F S T      E T      R  +T+    P PP+   
Sbjct: 3184 IEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQ 3243

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
            E++  + V  G P  F C V   G P  +I W+   +  +TG +   L+D     L +  
Sbjct: 3244 ELQP-VTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE 3300

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
             +  DA  YTC A N +G ATT+A ++           ++P+ +S ++            
Sbjct: 3301 AFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQ------------ 3338

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              E P+   PP  IT ++     E +  RF+CRV   +   L++ WY   K +     +R
Sbjct: 3339 --EMPVY--PPAIITPLQDTVTSEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFR 3391

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII---LQNQVPRG 3936
                     L+I   Y ED G Y   A N  G+  + A +S +    I+   ++ ++   
Sbjct: 3392 MTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEME 3451

Query: 3937 MK---------RSEALTQMEATIKKYTSEV-YLTEDDLY----DVDKK-QPPRFVTQI-Q 3980
            MK           E L   E  + K    +  L+E  +Y    D +K+   P F+ ++  
Sbjct: 3452 MKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSN 3511

Query: 3981 SQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYP 4040
            +  S+ ++ T      +  +G P  K++WFFNG  L     +  ++D    ++   +   
Sbjct: 3512 ADISMGDVAT----LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKL 3567

Query: 4041 EDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHM-KSIEKIREMEASWQVTPE 4099
            ED GEY C A+N YG     A +K   K     D++    + KS+EK+            
Sbjct: 3568 EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKL------------ 3615

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
                     CPP F+     +   +G  A F   V G P P V W      +     Y +
Sbjct: 3616 ------GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTI 3669

Query: 4160 TY--DGMYHFDIPKTRQYDTG 4178
             +  +G   F +   ++ D+G
Sbjct: 3670 IHNPNGSGTFIVNDPQREDSG 3690



 Score =  120 bits (290), Expect = 1e-25
 Identities = 130/547 (23%), Positives = 230/547 (42%), Gaps = 82/547 (14%)

Query: 1831 QRREDVEVAVN--QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
            + R  V + VN  + P+ + +L  P  +  G+ A +   I   P P  ++ WY   ++L 
Sbjct: 3224 RNRSSVTLYVNAPEPPQVLQELQ-PVTVQSGKPARFCAVISGRPQP--KISWYKEEQLLS 3280

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
            +G + +  +D     L ++  + ED+  YTC+A N+ G A +S  L+V+  E +  D + 
Sbjct: 3281 TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE- 3339

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008
                                      V  P    P+++   +EG P   +     V+   
Sbjct: 3340 ------------------------MPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTD 3372

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            ++V WY   + ++    F+ T       L+I  AY ED GTY   A+NAVG+  +T+++ 
Sbjct: 3373 LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 3432

Query: 2069 VDAKSGLYLDTLDEQ-------------------------RLKKIQELEKYERPKPI--- 2100
            ++A   +  + ++++                         +L KI E  +     P+   
Sbjct: 3433 LEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYST 3492

Query: 2101 --EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158
              + E+ G  P+F+  +++ + +  GD A     V  I  P   I WF NG  +     Y
Sbjct: 3493 KFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADY 3549

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLE 2218
            +   D    +L IL+T  ED G Y C A+N  G+ + +  LK+        DT+  + + 
Sbjct: 3550 KFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVA 3609

Query: 2219 KIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEF 2278
            K   LE  G             PP F+ EL+      +G  A FE  V  V +P   + +
Sbjct: 3610 K--SLEKLGGP----------CPPHFLKELK-PIRCAQGLPAIFEYTV--VGEPAPTVTW 3654

Query: 2279 YHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
            +   K L ++  + I  +  G  +  +     ED+G Y  KA N LG  T A  + V  +
Sbjct: 3655 FKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLE 3714

Query: 2338 GSIISES 2344
             + ++++
Sbjct: 3715 DTDMTDT 3721



 Score =  120 bits (290), Expect = 1e-25
 Identities = 128/511 (25%), Positives = 212/511 (41%), Gaps = 72/511 (14%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E PQ  + ++   V  G P    A ++    P  ++ WY   + +  G + K  +D    
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3294

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L ++ A+ ED   Y C+A N  G A T++S+ V                    E+ +  
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------------------EVPEVV 3334

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
             P   ++E P   P  +T L       EG  A F+CRV   +   L + W+   +KI+  
Sbjct: 3335 SP---DQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPS 3387

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII------- 2208
              +R T       L+I   Y ED GTY   A+N +G+  +T  L +    +I+       
Sbjct: 3388 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447

Query: 2209 LDTQHPNGLEKIRQLEAQG-HSTRIEVE----------EPKISPPRFVTELRGTTHVFEG 2257
            ++ +           E +G HS  +++           E  +   +F +E  GT  +F  
Sbjct: 3448 IEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIK 3507

Query: 2258 KTAHFECQVEPVHD--------PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
            + ++ +  +  V          P  +I+++ NG  L  +A +   FD    SL I     
Sbjct: 3508 EVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKL 3567

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPE 2369
            ED GEY+  A N  G    +  + + +KG         EG  K  E ESA      ++  
Sbjct: 3568 EDEGEYTCMASNDYGKTICSAYLKINSKG---------EG-HKDTETESAVAKSLEKLGG 3617

Query: 2370 PVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH 2429
            P     P F + L+ I    +G  A F+  +  VG+P   V WF+  K +  S   T  H
Sbjct: 3618 PCP---PHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIH 3671

Query: 2430 D-FGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +  G  +  ++  + ED G+Y+C+A N+LGE
Sbjct: 3672 NPNGSGTFIVNDPQREDSGLYICKAENMLGE 3702



 Score =  120 bits (289), Expect = 1e-25
 Identities = 100/404 (24%), Positives = 159/404 (39%), Gaps = 31/404 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+FT+K  P    +      + E  G P   + W ++   ++NS  F+I +    + L 
Sbjct: 7384 PPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLH 7443

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I  +   D   +   A N  G+  CS ++  +E          PP F     + +   G 
Sbjct: 7444 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE----------PPRFVKKLSDTSTLIGD 7493

Query: 4530 LVRLDTKVTGTKPIDVYWLKN-GKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
             V L   V G +PI V WLK+ G+ ++     +I   D   TL +      +SGKY C  
Sbjct: 7494 AVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQI 7553

Query: 4589 INSAGEARCDAECVVSLPA-TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
             N AG   C A   V  PA   +KP+P T                 V  G      C + 
Sbjct: 7554 KNDAGMRECSAVLTVLEPARIIEKPEPMT-----------------VTTGNPFALECVVT 7596

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P  + +W+K  + +       ++      +L+I  A   D+G Y     NS G+    
Sbjct: 7597 GTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT 7656

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              + V+  D+      +  L+D+    G     + +++     ++ W ++G  I   P  
Sbjct: 7657 VSVHVS--DRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKC 7714

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            Q     N   L +      DTG +TC A   AG  E SA L V+
Sbjct: 7715 QSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 7758



 Score =  120 bits (288), Expect = 2e-25
 Identities = 97/411 (23%), Positives = 171/411 (41%), Gaps = 34/411 (8%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
            G +   +PP F  K     V        +  F G     I+W++ N  + +     I   
Sbjct: 5125 GALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKE 5184

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            + +S L +  V   DS  +     N  G  +CSANL V+E          P +F    + 
Sbjct: 5185 ALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE----------PATFVEKLEP 5234

Query: 4523 VNVTS-GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
              +   G   +L  KVTGT PI + W  N ++++   ++++   + T  L + +   +DS
Sbjct: 5235 SQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDS 5294

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G+Y C A N AG   C +  +V       K  P       P E+++     ++AE     
Sbjct: 5295 GEYMCEAQNEAGSDHCSSIVIV-------KESPYFTKEFKPIEVLKEYDVMLLAE----- 5342

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
                + G P   + W+K + +++  + ++        +L+I +    D G+Y+C   N  
Sbjct: 5343 ----VAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEV 5398

Query: 4702 GRVTVAAKLKVTQPDQ-ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
            G    +A++ + +P      + + + LR      G  A F+  +   +  T+ WL++   
Sbjct: 5399 GSSICSARVTLREPPSFIKKIESTSSLR------GGTAAFQATLKGSLPITVTWLKDSDE 5452

Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            I E  + +M  E N A L +     +  G + C+A   AG    SA L VK
Sbjct: 5453 ITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK 5503



 Score =  120 bits (288), Expect = 2e-25
 Identities = 102/398 (25%), Positives = 171/398 (42%), Gaps = 38/398 (9%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P +  +K  P  V   E    E +  G P   ++WY++   + +S   +   ++  S L
Sbjct: 6629 EPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSL 6688

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I  V  +D+  +    +N  G + C+A + V ++        VPPSFT   +N     G
Sbjct: 6689 RILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA-------VPPSFTRRLKNTGGVLG 6741

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                L+ KV G+ PI V W     K+    + +    D   TL +      D G Y CVA
Sbjct: 6742 ASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVA 6801

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG   C A   V  P +  K +P            EPL+   V  G+ + F+  I G
Sbjct: 6802 ANVAGSDECRAVLTVQEPPSFVK-EP------------EPLE---VLPGKNVTFTSVIRG 6845

Query: 4649 KPLPTVQWYKGDK-LIKPSK---YFQMSRTADE-YTLRISEAFPEDEGDYKCVAYNSAGR 4703
             P   V W++G + L+K  +   YF+ +    E + + IS++     G+Y CV  N+AG+
Sbjct: 6846 TPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQS-----GEYTCVVSNNAGQ 6900

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             +   +L V +P        L  L D  V  G+    ++  T  +  ++ W ++G  I  
Sbjct: 6901 ASCTTRLFVKEP-----AAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITT 6955

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
            +    ++      +L I N+ + D G ++C     AG+
Sbjct: 6956 SEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGR 6993



 Score =  118 bits (283), Expect = 7e-25
 Identities = 97/404 (24%), Positives = 163/404 (40%), Gaps = 30/404 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP F KK++         A F+    G  LP+ + W +++  I    + ++   +  + 
Sbjct: 5411 EPPSFIKKIESTSSLRGGTAAFQATLKGS-LPITVTWLKDSDEITEDDNIRMTFENNVAS 5469

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L +  + V+    +   A+N  G  +CSA L V+E          P + T  A +++VT 
Sbjct: 5470 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE----------PATITEEAVSIDVTQ 5519

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G    L  K +GTK I   W K+G+++    + KI   D    L I+    +DSG+Y   
Sbjct: 5520 GDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFE 5579

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              N  G + C             K +        PP   + LK     +G  I+  C + 
Sbjct: 5580 VQNDVGRSSC-------------KARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVA 5626

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G    ++QW+K D+ I  S+ ++ S   +   L IS+    D G Y C A N AG    +
Sbjct: 5627 GSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCS 5686

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              L V +P      P     +   V      Q K  +      TI+W ++   +      
Sbjct: 5687 GHLTVKEPPYFVEKP-----QSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAAR 5741

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +  +  +  L +      D+GT+ C+ +   G   + A L VK
Sbjct: 5742 SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 5785



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/402 (25%), Positives = 159/402 (39%), Gaps = 30/402 (7%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FTK+ +P  V +        E  G P   I W+++N  +++   ++         L I
Sbjct: 5320 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQI 5379

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
             +    D+  +     N  G++ CSA + + E          PPSF    ++ +   G  
Sbjct: 5380 LKFVAADAGEYQCRVTNEVGSSICSARVTLRE----------PPSFIKKIESTSSLRGGT 5429

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
                  + G+ PI V WLK+  ++  D   ++  E+   +L +     +  GKY C A N
Sbjct: 5430 AAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKN 5489

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
             AG  RC A   V  PAT                I E      V +G       K  G  
Sbjct: 5490 DAGIQRCSALLSVKEPAT----------------ITEEAVSIDVTQGDPATLQVKFSGTK 5533

Query: 4651 LPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
              T +W+K G +L   SKY ++S T     L+I     +D G+Y     N  GR +  A+
Sbjct: 5534 EITAKWFKDGQELTLGSKY-KISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKAR 5592

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            + V   D          L+ +   +G     +  +      +IQW ++   I  +  ++ 
Sbjct: 5593 INVL--DLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 5650

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                N A L I      D+GT+TC AT  AG  + S  L VK
Sbjct: 5651 SFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 5692



 Score =  115 bits (276), Expect = 5e-24
 Identities = 119/511 (23%), Positives = 203/511 (39%), Gaps = 50/511 (9%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  K      G +   E K+ G+P   VSW  +   +    KY     + T   +
Sbjct: 8608 PPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT--CA 8665

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L +  +   D G+YTC A N  G   CS  +                     + T     
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIV 8725

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF-KVDTFEYRLLREVSFRESITKRYVGESD 249
             GT  ++    + + ++   +  + S  D   +++ F+    +   +   I     G++ 
Sbjct: 8726 KGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYT-CIVSNEAGKAS 8784

Query: 250  VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
                  I       +P K  ++  +  +++G     +   +G P   VTW KNG  +  S
Sbjct: 8785 CTTHLYIK------APAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPS 8838

Query: 310  NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  I T           T+KS       + E P+  +  +G              Q + 
Sbjct: 8839 QRCNITT-----------TEKS------AILEIPSSTVEDAG--------------QYNC 8867

Query: 370  YITDTQQRET-EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            YI +   +++   +I I E    P FVK  +   V+ G      C++ G P   V+W+  
Sbjct: 8868 YIENASGKDSCSAQILILEP---PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKG 8924

Query: 429  DRQIRDDYNHKILVNESGNHALMITN-VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
            D ++R    +K+  +   N A ++ N V ++DSG   C A N  GE +    L V  +EQ
Sbjct: 8925 DTKLRPTTTYKM--HFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV--QEQ 8980

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
             + P F  +   +    G PVV +    G+    ++W KDG P+  +P ++       +T
Sbjct: 8981 KLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTAT 9040

Query: 548  LDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            L+I +   S A  Y CTA N  GS ++ ARL
Sbjct: 9041 LNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071



 Score =  113 bits (272), Expect = 1e-23
 Identities = 94/404 (23%), Positives = 151/404 (37%), Gaps = 31/404 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP FT++++            E +  G     + W+ E   I +   +Q         L 
Sbjct: 6726 PPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQ 6785

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  +   D   +  VA N  G+ +C A L V+E          PPSF    + + V  G+
Sbjct: 6786 LNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE----------PPSFVKEPEPLEVLPGK 6835

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V   + + GT P  V W +  +++    R  I  ED    L +       SG+Y CV  
Sbjct: 6836 NVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVS 6895

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N+AG+A C     V  PA                  ++ L D  V  G++I       G 
Sbjct: 6896 NNAGQASCTTRLFVKEPAA----------------FLKRLSDHSVEPGKSIILESTYTGT 6939

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
               +V W K    I  S+   +  T     L I  +   D G Y C   N AGR    A 
Sbjct: 6940 LPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGAL 6999

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            +   +P     +  L PL   V   G     + Q+    + T+ W +    +  TP+++ 
Sbjct: 7000 VSTLEPPYF--VTELEPLEAAV---GDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRT 7054

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                N A L+       D+G +TC+A  + G   +     ++ +
Sbjct: 7055 YFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 7098



 Score =  113 bits (271), Expect = 2e-23
 Identities = 143/649 (22%), Positives = 258/649 (39%), Gaps = 54/649 (8%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH-DFGYVALDILYTYAEDSGT 2181
            EG    F C++     P +   W+ +G++I+ G RY+      G  +L I     ED G 
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIA--WYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361

Query: 2182 YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLEAQGHS-TRIEVEEPK 2238
            Y   A+N  G A+ +  L V     +   T  P    + +IR L  +  S + I +   +
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPAR 1421

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHF--ECQVEPVHDPNLRIEFYHNGKALQS-AARFHITF 2295
            +SP R          +  G+      E Q+E ++ P   ++   + K L+   ARF +  
Sbjct: 1422 MSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV-SFKCLEGQTARFDLKV 1480

Query: 2296 DFGYVSLDIQ-HCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQRPEGLEK 2352
                +      H   +   +Y+ K +       S I +  T    G     +Q   G   
Sbjct: 1481 VGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSS 1540

Query: 2353 IRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEW 2412
            I  + + E  +         + +P+F + L+N+ NI+EG  +  + ++   G+P   + W
Sbjct: 1541 ISVILTVEAVEH--------QVKPMFVEKLKNV-NIKEG--SQLEMKVRATGNPNPDIVW 1589

Query: 2413 FRNEKLIEDSS--RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXX 2470
             +N  +I      +I      G  ++ I     +D   Y   A N  G            
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649

Query: 2471 XXXIQLETQH----PEGMKKIQKLEQP-----HERRSEEP-------DREFE-KPIFTQV 2513
                + E +     P G  + +++  P     H R  +E        D+E + KP F + 
Sbjct: 1650 EFA-EPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1708

Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSV 2573
            LT    L     AH+E R+ P+GDP++  EW  +G  L+  +R R  ++FG+ +LD    
Sbjct: 1709 LTS-LRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVA 1767

Query: 2574 VANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPE-- 2631
             + D+G+  C+A N+ G               +++++  PE  + +Q  E       E  
Sbjct: 1768 YSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGA 1827

Query: 2632 ---MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
               +  D   +Q P    + +   +++EG+      +V     P  K+ W+ NG  +   
Sbjct: 1828 LTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKS 1884

Query: 2689 ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             R +  +D G+  L I   ++ D+G     A N  G       ++I+ R
Sbjct: 1885 KRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1932



 Score =  111 bits (268), Expect = 5e-23
 Identities = 89/371 (23%), Positives = 148/371 (39%), Gaps = 28/371 (7%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVV 4500
            + WY EN  + +   F+         L+I +V  ED    +   A N  G    SA L V
Sbjct: 4318 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4377

Query: 4501 EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN 4560
             ++          P      + + V  G L +   ++     +   W K G+++    + 
Sbjct: 4378 VKR--------AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4429

Query: 4561 KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAAN 4620
             I       +L IL     D G+Y C A N  G   C A   V            T+A  
Sbjct: 4430 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV------------TEAY- 4476

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
             PP  +   K      G+A +F C + G P+    W K    + PS  +++S   +++ L
Sbjct: 4477 -PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHIL 4535

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             +S    +D G Y C A N  G     A+L +   D+   +  L P++  +    +    
Sbjct: 4536 ELSNLTIQDRGVYSCKASNKFGADICQAELIII--DKPHFIKELEPVQSAI---NKKVHL 4590

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + Q+    K T+ W ++G  +P   D+++  E   A L I     +D+GT+ C A+  AG
Sbjct: 4591 ECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAG 4650

Query: 4801 QVETSAKLVVK 4811
                SA + V+
Sbjct: 4651 SSSCSATVTVR 4661



 Score =  111 bits (266), Expect = 8e-23
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 11/228 (4%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS--PDFQIHTFSTK 4465
            ++ P FT+ +Q   V E   A FE    G P+P + W+R+   I  S  P  QI     +
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            + L I  V   +S  ++  A N  G A  +A L+V+ +         PP+F    Q++ V
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET-------APPNFVQRLQSMTV 115

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  VRL  +VTG     V + ++G ++Q  +  +I +E   Y+LLI EAYP+DSG Y 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
              A NS G A   AE +V     ++ P  +TK   +  +I E  + +I
Sbjct: 176  VNATNSVGRATSTAELLVQ--GEEEVPAKKTKTIVSTAQISESRQTRI 221



 Score =  109 bits (263), Expect = 2e-22
 Identities = 118/513 (23%), Positives = 192/513 (37%), Gaps = 51/513 (9%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  +      G N  F   +RG P   V+W R    LV+ ++ ++ + +   ++ 
Sbjct: 6819 PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELE 6878

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L    I     GEYTC   N  G+A C+  +  +                  S  +E   
Sbjct: 6879 LF--NIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTY 6936

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             GT   +    +        +G + ++++   + T E   + E+    + TKR  G+   
Sbjct: 6937 TGTLPISVTWKK--------DGFNITTSEKCNIVTTEKTCILEIL---NSTKRDAGQYSC 6985

Query: 251  QISTEIDRS-----LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
            +I  E  R      +  + PP    +    +   G     Q Q++G P   V+W+K   +
Sbjct: 6986 EIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTK 7045

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
            L  + ++    T+N  TL       +DSG YT  AEN  G           S T   +Q+
Sbjct: 7046 LRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIG--------TASSKTVFRIQE 7097

Query: 366  QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
            ++       Q ++ E+ +                      G      CR+ G    +V W
Sbjct: 7098 RQLPPSFARQLKDIEQTV----------------------GLPVTLTCRLNGSAPIQVCW 7135

Query: 426  FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
            + +   +RDD N +    ++    L I    LS SG  +C A N  G  +   RL   E 
Sbjct: 7136 YRDGVLLRDDENLQTSFVDN-VATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREP 7194

Query: 486  EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545
            ++  +P F  +  +++V  GE         G    RITW KD   I P     I   G  
Sbjct: 7195 KK--SPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNT 7252

Query: 546  STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              L I +    D+  Y C A N  G     A+L
Sbjct: 7253 PHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 7285



 Score =  109 bits (261), Expect = 3e-22
 Identities = 69/234 (29%), Positives = 108/234 (46%), Gaps = 14/234 (5%)

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            A ++  R   A+ S    +EE        +  P F L   +     GQ  R D KV G  
Sbjct: 1425 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRP 1484

Query: 4542 PIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
              + +W  +G+++  D  +K+ ++EDGT +L+I+ A P DSG++  VA N AG  R    
Sbjct: 1485 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG--RSSIS 1542

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             ++++ A + + KP           +E LK+  + EG  +E   +  G P P + W K  
Sbjct: 1543 VILTVEAVEHQVKPM---------FVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNS 1593

Query: 4661 KLIKPSKY--FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +I P KY   ++  T  E  L+I     +D   Y   A N AGR T   K+ V
Sbjct: 1594 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647



 Score =  108 bits (259), Expect = 6e-22
 Identities = 89/314 (28%), Positives = 140/314 (44%), Gaps = 38/314 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP    KP +  +  G+    +    G+    + WFK  + L++     I      ++L 
Sbjct: 5132 PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLE 5191

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +   + SDSG YT    N     V  G   VE     +V++  + ++         E++E
Sbjct: 5192 LYLVKTSDSGTYTCKVSN-----VAGG---VECSANLFVKEPAT-FV---------EKLE 5233

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
             S      Q +K        +G  T+  C+VTG P  ++TWF NDR+I++   H++   E
Sbjct: 5234 PS------QLLK--------KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVE 5279

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
            S    L +T+V + DSG   C A+N++G     C   VI KE   +P F + F  + V +
Sbjct: 5280 S-TAVLRLTDVGIEDSGEYMCEAQNEAGSD--HCSSIVIVKE---SPYFTKEFKPIEVLK 5333

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
               V+L A   GTP   ITW KD   +    + +        +L I +  A+DA  YQC 
Sbjct: 5334 EYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCR 5393

Query: 565  AQNVAGSTATRARL 578
              N  GS+   AR+
Sbjct: 5394 VTNEVGSSICSARV 5407



 Score =  107 bits (256), Expect = 1e-21
 Identities = 179/750 (23%), Positives = 286/750 (38%), Gaps = 90/750 (12%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYING--VELKMGSRFRTTHDFG 2564
            KP+F + L   + + EG  +  E +V   G+P+    W  N   +      + R     G
Sbjct: 1555 KPMFVEKLKNVN-IKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKG 1611

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXX--------IIDQAM-RPES 2615
               L I+S V+ D+  Y   AIN+AG                       II +   R + 
Sbjct: 1612 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKE 1671

Query: 2616 WEQIQLKEAAMNKVPEMF-----VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRT 2670
                +L+   +    E +      D   QQ P F   L S  +L      + E ++ P  
Sbjct: 1672 IAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPIG 1730

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DP + +EW  +G  L    RL+   +FG  +L      + DSGI TC+ATN  G   ++A
Sbjct: 1731 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1790

Query: 2731 SIKIEDRHWLLGESLHPD---SLDRIGALXXXXXXXXXXXXXXXXXXV----FISHLNNI 2783
            ++ ++D   L+ ES  P+    L RI  L                        + +   +
Sbjct: 1791 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1850

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
               EG+   F C V     P  K+ W+ N + +    R++  +D  +  LDI      D+
Sbjct: 1851 RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYDGIHY-LDIVDCKSYDT 1907

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
            G     A N +G                    +H   K  LE ++Q E+ R    R P  
Sbjct: 1908 GEVKVTAENPEGV------------------IEH---KVKLE-IQQREDFRSVLRRAPE- 1944

Query: 2904 PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLK-IEWYFNGKVLEQG----S 2958
                 P+PE+ +    + Q    +V       E K    LK  E   + KV E+     S
Sbjct: 1945 -----PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRS 1999

Query: 2959 RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKG 3018
            +FK  ++ G+   + +   E  S         K+ E++    +   +KD L+  T+  + 
Sbjct: 2000 KFKRRTEEGY--YEAITAVELKS--------RKKDESY--EELLRKTKDELLHWTK--EL 2045

Query: 3019 TEGLEKIQNLEDSLRKEPGQQPDDDTGRPP-EFTTVFKDIVD--ISEGQIAHYEASLIPT 3075
            TE  EK    E+     P  +PD     P  E   +F+ I    + +G  AH+   ++  
Sbjct: 2046 TEE-EKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVV-- 2102

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAEI 3134
            G      EW+ NG  IE S RI   +    V  L I      DS +   +A N  G+   
Sbjct: 2103 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2162

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L    K   Q   FT  +Q++   +    A FEC      +P +K++WY +G  +  
Sbjct: 2163 HAFLLVQAK---QLITFTQELQDVVAKEKDTMATFEC---ETSEPFVKVKWYKDGMEVHE 2216

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              + +  SD     L I      D+ +Y C
Sbjct: 2217 GDKYRMHSDRKVHFLSILTIDTSDAEDYSC 2246



 Score =  106 bits (255), Expect = 2e-21
 Identities = 88/333 (26%), Positives = 147/333 (44%), Gaps = 25/333 (7%)

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIV----PPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            E    +++     V   K ++  GG +    P   T     V+   G +V L T +T  K
Sbjct: 4258 EKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAK 4316

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD-SGKYECVAINSAGEARCDAE 4600
              +V W    K V  D + K L++  TYTL+I +   +D  G+Y C A+N +G+    A+
Sbjct: 4317 --EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAK 4374

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V             +AA      IEPL+   VA G   +F+C+I   P    QW+K  
Sbjct: 4375 LTVV-----------KRAAPVIKRKIEPLE---VALGHLAKFTCEIQSAPNVRFQWFKAG 4420

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            + I  S    +  +    +L I      D G+Y C A N  G V+  A L VT+   A  
Sbjct: 4421 REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTE---AYP 4477

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               L+  + +  + G+ A+F   +T        W ++GA +  +P++++    N  +L +
Sbjct: 4478 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILEL 4537

Query: 4781 GNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             N   +D G ++C+A+   G     A+L++  K
Sbjct: 4538 SNLTIQDRGVYSCKASNKFGADICQAELIIIDK 4570



 Score =  105 bits (252), Expect = 4e-21
 Identities = 128/514 (24%), Positives = 209/514 (40%), Gaps = 78/514 (15%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++ G  A F A +   G    ++ W K+ + +    +     +     L +      D
Sbjct: 3248 VTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 3305

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK 1038
            A  YTC A N  G ATTSA+L++   + +  + + P                        
Sbjct: 3306 AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP------------------------ 3341

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
                P  + PL+ T    EGQ A F+ RV   S   + V WY   K+I  +   +     
Sbjct: 3342 -VYPPAIITPLQDT-VTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFE 3396

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI--------------DTS 1144
                L+IA    ED G YT VA NA G+   +A++++E   SI              + S
Sbjct: 3397 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFS 3456

Query: 1145 SIHRGLYEKTRHIEE---SKFVE--------PMYQIEEISKSK---PVFVQPLSNPPPVS 1190
            S      E+  H  E   SK  E        P+Y  +  S+ +   P+F++ +SN   +S
Sbjct: 3457 SSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSN-ADIS 3515

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
             G    L   +  +G P  +++WF NG  +T  + +K  +D    +L I+     D GEY
Sbjct: 3516 MGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEY 3573

Query: 1251 TVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA 1310
            T  A N  G    SA +++  + +   DT+ E A+             K + E +     
Sbjct: 3574 TCMASNDYGKTICSAYLKINSKGEGHKDTETESAV------------AKSL-EKLGGPCP 3620

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L  I   +G     E  +  VG+    V WF   K + T   +   +  +    
Sbjct: 3621 PHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGT 3678

Query: 1371 DLLS-VYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             +++    EDSG+Y C+A N LGE+  +  L V+
Sbjct: 3679 FIVNDPQREDSGLYICKAENMLGESTCAAELLVL 3712



 Score =  104 bits (249), Expect = 9e-21
 Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 19/258 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN--KILEEDGTYTL 4571
            P+FT   Q+V V  G     +  ++G    +V W ++G+ +        +I   DG   L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      +SG+Y   A N +G+A   AE +V             KA  APP  ++ L+ 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------KAETAPPNFVQRLQS 112

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V +G  +    ++ G P P V++Y+    I+ S  FQ+S+  D Y+L I+EA+PED G
Sbjct: 113  MTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK-- 4749
             Y   A NS GR T  A+L V   ++       T +    + E +  + + +I +     
Sbjct: 173  TYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDAR 232

Query: 4750 --PTIQWLREGALIPETP 4765
               T++ + +GA   + P
Sbjct: 233  SIATVEMVIDGAAGQQLP 250



 Score =  104 bits (249), Expect = 9e-21
 Identities = 170/774 (21%), Positives = 288/774 (37%), Gaps = 105/774 (13%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            ++ +W  NG +I S ++ Q        +L+I +V   D+  YT VA  A   A L     
Sbjct: 2997 ISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEAR 3056

Query: 1135 -VETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGK 1193
             +E R  I    +     EK R + E +  EP   ++ +   + +    +++   + + K
Sbjct: 3057 HIEFRKHIKDIKV----LEKKRAMFECEVSEPDITVQWMKDDQEL---QITDRIKIQKEK 3109

Query: 1194 NIHL----ECRLEPMGDPTM-------RVEWFHNGRSVTVGSRFKTYYDFGFVALDI--- 1239
             +H       R+   G  T+         + F  GR V + S  K           +   
Sbjct: 3110 YVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFE 3169

Query: 1240 IHATSADTGEYT--VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARR 1297
            ++    D   Y   +     +   H   + R I R   +++T+   A E   +   A R 
Sbjct: 3170 VNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM-FISETRQSDAGEYTFV---AGRN 3225

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
               V   +   + PQ  + L  +    G      C +   G    ++ W+   + + TG 
Sbjct: 3226 RSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGF 3283

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSG 1417
            + +  ++     L L+  +PED+ VYTC+A N  G A TS +L V   + +  + + P  
Sbjct: 3284 KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP-- 3341

Query: 1418 LEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK 1477
                                    + P  +  P       EGQ   F+C+   V+ ++LK
Sbjct: 3342 ------------------------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLK 3374

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            V W+   + +     FR         L+I +   ED G YT  A N VG    +  L+  
Sbjct: 3375 VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3434

Query: 1538 STTDIVRS------------------TQNEAGLEQIQV----------LEDRSKYHRTDM 1569
            +   I+                    +  E GL   ++          L   S  + T  
Sbjct: 3435 APESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKF 3494

Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629
              E     PI    + N +I  G  A     +I +     K++W+ N   L   + +   
Sbjct: 3495 DSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFV 3552

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN 1689
             +    +L I+    ED G YTC A N  G+ + S    ++SK   + +++ E A+ +  
Sbjct: 3553 FDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK-- 3610

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRN 1749
             LE                  P F   +K IR A+   A FE  +  VG+P   V W + 
Sbjct: 3611 SLEKLGG-----------PCPPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKE 3657

Query: 1750 GVPIEASNRLTTMHD-FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
               +  S   T +H+  G     +     EDSG Y C+A N LGE+  ++ L V
Sbjct: 3658 NKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3711



 Score =  103 bits (247), Expect = 2e-20
 Identities = 124/483 (25%), Positives = 190/483 (39%), Gaps = 78/483 (16%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W+   Q +  G + +  HD     L ++  + ED+  Y C+A N  G A  + +
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325

Query: 2199 LKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            L V     +  D + P                        + PP  +T L+ T    EG+
Sbjct: 3326 LSVEVPEVVSPDQEMP------------------------VYPPAIITPLQDTV-TSEGQ 3360

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT-FDFGYVSLDIQHCVPEDAGEYSV 2317
             A F+C+V      +L++ +Y   K ++ +  F +T F+  Y  L+I    PED G Y+ 
Sbjct: 3361 PARFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTY-QLEIAEAYPEDEGTYTF 3416

Query: 2318 KAINALGHCTSAISMTVTAKGSIISE------------------SQRPEGLE-------K 2352
             A NA+G  +S  ++++ A  SI+ E                  S   EGL        K
Sbjct: 3417 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3476

Query: 2353 IRE---LESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            I E   L S  P    +         P+F + + N D I  G  A     +I  G P  K
Sbjct: 3477 INETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTVI--GIPKPK 3533

Query: 2410 VEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXX 2469
            ++WF N  L+  S+      D    S+ I   + EDEG Y C ASN  G+          
Sbjct: 3534 IQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKIN 3593

Query: 2470 XXXXIQLETQHPEGM-KKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528
                   +T+    + K ++KL  P              P F + L  P    +G  A +
Sbjct: 3594 SKGEGHKDTETESAVAKSLEKLGGPC------------PPHFLKELK-PIRCAQGLPAIF 3640

Query: 2529 EARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAIN 2587
            E  V  VG+P+    W+    +L     +   H+  G  T  +N     D+GLY+CKA N
Sbjct: 3641 EYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3698

Query: 2588 RAG 2590
              G
Sbjct: 3699 MLG 3701



 Score =  103 bits (246), Expect = 2e-20
 Identities = 165/808 (20%), Positives = 292/808 (36%), Gaps = 69/808 (8%)

Query: 67   GEPSPPIFEQIFKNARFA-QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            G   PP F +  + +R   Q    ++E K+ G+P   V W + +  + E +K+ M + + 
Sbjct: 8227 GVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDS 8286

Query: 126  TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET 185
               + +    +   D G+YTC A N  G A  S  ++ +               +     
Sbjct: 8287 VAVLEM--HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVH 8344

Query: 186  VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
            +E +  GT  +     +  +++   +G  +    +  + +     +      E   K   
Sbjct: 8345 LECELQGTPPFHVSWYKDKRELR--SGKKYKIMSENFLTSIHILNVDAADIGEYQCK--- 8399

Query: 246  GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
              +DV   T +  S+   +PP+  +K  +     G + Q Q  + G     V WFK    
Sbjct: 8400 ATNDVGSDTCVG-SIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFK---- 8454

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
                +K EI+             ++SD+  +   +EN    I T  +  VE         
Sbjct: 8455 ----DKGEIV-------------RESDN-IWISYSEN----IATLQFSRVEPANAG---K 8489

Query: 366  QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
               Q   D   +E    + + E A     V+  +   VT G     +C V G P     W
Sbjct: 8490 YTCQIKNDAGMQECFATLSVLEPAT---IVEKPESIKVTTGDTCTLECTVAGTPELSTKW 8546

Query: 426  FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
            F + +++  D  +KI      +  L I NV  SDSGV +   +N  G+ +    L V   
Sbjct: 8547 FKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV--S 8603

Query: 486  EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545
            ++ V P F  +    N   G  VV+  +  G+P   ++W  +G  I    + +       
Sbjct: 8604 DRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT 8663

Query: 546  STLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXX 605
              L +   + SD+  Y C A N+AGS    A L              + +   T V    
Sbjct: 8664 CALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTS 8723

Query: 606  XXXXXXXXYLRHVERARPYIPPGE-----EDRVYPPPQFIVPLKS------VTAMEGGKI 654
                     +   + +   +P        ED V     F V          + + E GK 
Sbjct: 8724 IVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKA 8783

Query: 655  HFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAV 714
               T +  +  P   ++ L N  SIE       I    +     +S+  + +G     + 
Sbjct: 8784 SCTTHLY-IKAPAKFVKRL-NDYSIEKGKPL--ILEGTFTGTPPISVTWKKNGINVTPSQ 8839

Query: 715  SATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIR 774
                    K+ +   P +T+E   Q+     YI+          Q  I E     P F++
Sbjct: 8840 RCNITTTEKSAILEIPSSTVEDAGQYN---CYIENASGKDSCSAQILILEP----PYFVK 8892

Query: 775  PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMH 834
             L+ + ++  G +A  + QL     P + V WYK    +  ++     F     +L    
Sbjct: 8893 QLEPV-KVSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQ 8949

Query: 835  LRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +   D+G Y  +A N +GE  ++  + V
Sbjct: 8950 VDINDSGEYICKAENSVGEVSASTFLTV 8977



 Score =  102 bits (244), Expect = 4e-20
 Identities = 70/234 (29%), Positives = 108/234 (46%), Gaps = 16/234 (6%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV+PP +    +N  + EG     +  +SG P P VTW++   ++ +S   +I       
Sbjct: 939  PVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIA 998

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE----------SPTESYVQDQR---- 367
             L +R     DSG +T  A N  G + TS YLAV+          + TE +  +++    
Sbjct: 999  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1058

Query: 368  SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            S+ +  T    TEE+    E A AP F+     + + EG    F C+V G P P V W  
Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPA-APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1117

Query: 428  NDRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            +   +   Y +K+  N ++G   L+I+     D+G  T V RNK GET+    L
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score =  100 bits (240), Expect = 1e-19
 Identities = 76/284 (26%), Positives = 123/284 (43%), Gaps = 8/284 (2%)

Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITS----T 4385
            +EV     Q+ V +     D  ++  +   + +  Q Q + + V ++ I R   S    +
Sbjct: 3154 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3213

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445
            +  E    A      V   V   +PP   +++QP  V   + ARF     G P P I WY
Sbjct: 3214 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3273

Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR- 4504
            +E   +      +      +  L++ + F ED+AV+   A+N  G A  SA+L VE    
Sbjct: 3274 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3333

Query: 4505 --RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                    + PP+     Q+   + GQ  R   +V+GT  + V W    KK++P    ++
Sbjct: 3334 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRM 3392

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
             + + TY L I EAYP+D G Y  VA N+ G+    A   +  P
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436



 Score =  100 bits (239), Expect = 1e-19
 Identities = 113/503 (22%), Positives = 189/503 (37%), Gaps = 44/503 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            PQ ++  Q   V  GK  RF   ++GRP P+++W+  ++ +   +  K L ++   + L+
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL-HDGQEYTLL 3297

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLN-----VIEKEQ---VVAPKFVERFSTLNVR 503
            +      D+ V TC A+N  G       L+     V+  +Q   V  P  +         
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3357

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            EG+P     R  GT   +++W      I P+   R+        L+I  A   D   Y  
Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3416

Query: 564  TAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTK-------------VXXXXXXXXX 610
             A N  G  ++ A L           +    +    K             +         
Sbjct: 3417 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3476

Query: 611  XXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKI 670
                L  +  +  Y    + ++    P FI  + +     G        +  +  P  KI
Sbjct: 3477 INETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP--KI 3534

Query: 671  EWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTP 730
            +W  NG  +  S+ +  +F     SL +L   ++D GEYTC A +  G     A L +  
Sbjct: 3535 QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3594

Query: 731  RATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ-RPQFIRPLQDLGELQEGRNAH 789
            +        H +T       E  S     +S+E+      P F++ L+ +    +G  A 
Sbjct: 3595 KG-----EGHKDT-------ETESAV--AKSLEKLGGPCPPHFLKELKPI-RCAQGLPAI 3639

Query: 790  FEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGYVSLNIMHLRAEDAGSYTVRAV 848
            FE   T V +P   V W+K+ + +  S   T I N  G  +  +   + ED+G Y  +A 
Sbjct: 3640 FE--YTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAE 3697

Query: 849  NKLGEAISTASIRVAARSTVTAD 871
            N LGE+   A + V    T   D
Sbjct: 3698 NMLGESTCAAELLVLLEDTDMTD 3720



 Score =   99 bits (238), Expect = 2e-19
 Identities = 139/561 (24%), Positives = 209/561 (37%), Gaps = 77/561 (13%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   Q LQ +  +Q G+ A F C +I  G P  K+ W++ E+L+    +    HD    +
Sbjct: 3239 PQVLQELQPV-TVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495
            + +     ED  VY C A N  G                 L  + PE +           
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSAS----------LSVEVPEVVS---------- 3335

Query: 2496 RRSEEPDREFEKPIFTQVLTGPSE---LWEGQHAHYEARVVPVGDPSLRFEWYINGVELK 2552
                 PD+E   P++   +  P +     EGQ A ++ RV       L+  WY    ++K
Sbjct: 3336 -----PDQEM--PVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIK 3385

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMR 2612
                FR T       L+I      D G Y   A N  G               I+ + + 
Sbjct: 3386 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIE 3445

Query: 2613 PE-SWEQIQLKEAAMNKVPEMFVDTGVQ------------QAPIFTTHLKS--------Y 2651
             E   E  +   + ++   E      +Q            ++P+++T   S        +
Sbjct: 3446 QEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIF 3505

Query: 2652 DKLVEGQHVYL----EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             K V    + +       V     P  KI+WF NGV LT  A  K  FD    +L I   
Sbjct: 3506 IKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFT 3565

Query: 2708 RNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXX 2767
            + +D G YTC A+N  G+ + +A +KI  +    GE  H D+ +   A+           
Sbjct: 3566 KLEDEGEYTCMASNDYGKTICSAYLKINSK----GEG-HKDT-ETESAVAKSLEKLGGPC 3619

Query: 2768 XXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD 2827
                    F+  L  I C +G    FE  V     PT  + WF  NK L +   Y   H+
Sbjct: 3620 PPH-----FLKELKPIRCAQGLPAIFEYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHN 3672

Query: 2828 FSYVSLDITH-TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEA 2886
             +     I +    EDSG+Y CKA N  G +T +  L    +     DT   + K+  EA
Sbjct: 3673 PNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP-CKAKSTPEA 3731

Query: 2887 VEQAEEARLAKGRRPSVPDTE 2907
             E   +  L KG      D+E
Sbjct: 3732 PEDFPQTPL-KGPAVEALDSE 3751



 Score =   99 bits (238), Expect = 2e-19
 Identities = 101/463 (21%), Positives = 193/463 (41%), Gaps = 28/463 (6%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            + K+ +   +EC +  S  P +K+ W+ +   +   ++++ +   S   L++ +   EDS
Sbjct: 8243 IVKQDEFTRYECKIGGS--PEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDS 8300

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHP-QGKAGLEAVEQAEEARLAKGRRPS 2902
            G YTC+A N+ GSA++S SL+   +  I+    HP +   G +   + E           
Sbjct: 8301 GDYTCEAHNAAGSASSSTSLKVK-EPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSW 8359

Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLE----GQVEPKNDPDLKIEWYFNGKVLEQGS 2958
              D    +      I +E+ L    +L+++    G+ + K   D+  +       L+   
Sbjct: 8360 YKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP 8419

Query: 2959 RF-KLTSDFGFVTLDLVDVYERDSGIYTCKA--YNKRGEAFTSS-TVYCTSKDNL--IER 3012
            RF K  SD   V    V +     G        +  +GE    S  ++ +  +N+  ++ 
Sbjct: 8420 RFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQF 8479

Query: 3013 TQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFK--DIVDISEGQIAHYEA 3070
            ++      G    Q     ++ + G Q    T    E  T+ +  + + ++ G     E 
Sbjct: 8480 SRVEPANAGKYTCQ-----IKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLEC 8534

Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
            ++  T + S   +WF +GK + + ++ +  +   +  L+I+    +DSG YS    N  G
Sbjct: 8535 TVAGTPELST--KWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVG 8592

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            +   +  L+  D++    P FT  ++   GL  G S   EC V     P + + W+H G 
Sbjct: 8593 KDSCTASLQVSDRT--VPPSFTRKLKETNGL-SGSSVVMECKV--YGSPPISVSWFHEGN 8647

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +    + +T        L +   +  DSG+Y C A N  G D
Sbjct: 8648 EISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSD 8690



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 57/193 (29%), Positives = 97/193 (50%), Gaps = 4/193 (2%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYTL 4680
            P   +PL+  +V EG    F   I G P+P V W++  ++I  S     Q+S +     L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             I      + G Y   A N +G+ T  A+L V       N   +  L+ + V +G   + 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNF--VQRLQSMTVRQGSQVRL 123

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + ++T    P +++ R+GA I  + DFQ+  EG+   LLI   Y ED+GT++  AT + G
Sbjct: 124  QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183

Query: 4801 QVETSAKLVVKSK 4813
            +  ++A+L+V+ +
Sbjct: 184  RATSTAELLVQGE 196



 Score = 98.3 bits (234), Expect = 6e-19
 Identities = 87/371 (23%), Positives = 151/371 (40%), Gaps = 56/371 (15%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV PP I    +++   EG  A+FQ ++SG    +V+W+   +++  S    +    +  
Sbjct: 3341 PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3399

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLA-----------VESPTESYVQDQRSQY 370
             L +      D G YT +A N  G + ++  L+           +E   E  +++  S +
Sbjct: 3400 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSF 3459

Query: 371  IT---------DTQQRETEERIEI------------SEK-ALAPQFVKVCQDRDVTEGKM 408
            ++         + Q  +  E +E+            SEK    P F+K   + D++ G +
Sbjct: 3460 LSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDV 3519

Query: 409  TRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
                  V G P P++ WF N   +    ++K  V +  +H+L+I    L D G  TC+A 
Sbjct: 3520 ATLSVTVIGIPKPKIQWFFNGVLLTPSADYKF-VFDGDDHSLIILFTKLEDEGEYTCMAS 3578

Query: 469  NKSGETAFQCRLNV---------IEKEQVVA-----------PKFVERFSTLNVREGEPV 508
            N  G+T     L +          E E  VA           P F++    +   +G P 
Sbjct: 3579 NDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPA 3638

Query: 509  VLNARAVGTPTPRITWQKDGVPIIPNPELR-IHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +     VG P P +TW K+   +  +     IH   G+ T  +   +  D+  Y C A+N
Sbjct: 3639 IFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3698

Query: 568  VAGSTATRARL 578
            + G +   A L
Sbjct: 3699 MLGESTCAAEL 3709



 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 60/189 (31%), Positives = 89/189 (47%), Gaps = 6/189 (3%)

Query: 388  KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447
            +A  P F+   +      GK  +F C VTG P  E  W  +   +    N KI   E+  
Sbjct: 4474 EAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAEN-K 4532

Query: 448  HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            H L ++N+T+ D GV +C A NK G    Q  L +I+K     P F++    +     + 
Sbjct: 4533 HILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK-----PHFIKELEPVQSAINKK 4587

Query: 508  VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            V L  +        +TW KDG  + P  + +I  +   +TL+IP AK  D+  Y CTA N
Sbjct: 4588 VHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASN 4647

Query: 568  VAGSTATRA 576
             AGS++  A
Sbjct: 4648 EAGSSSCSA 4656



 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 110/509 (21%), Positives = 189/509 (37%), Gaps = 46/509 (9%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  KN     G +   E K+ G+    V+W  +K  +V   KY   +++     +
Sbjct: 6726 PPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNV--CT 6783

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L +  +   D G YTC A N  G   C   +  +                  + T     
Sbjct: 6784 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVI 6843

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             GT  +     R  +++           + +  DT     L  +   +S     V  ++ 
Sbjct: 6844 RGTPPFKVNWFRGAREL-----VKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNA 6898

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
              ++   R L    P    ++  +  ++ G     +   +G     VTW K+G  +  S 
Sbjct: 6899 GQASCTTR-LFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSE 6957

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
            K  I+TT     L + N+ K D+G Y+   EN  G  V    ++   P           +
Sbjct: 6958 KCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEP---------PYF 7008

Query: 371  ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEV-TWFIND 429
            +T+         +E  E A+       CQ     E  ++ +      RP PE  T+F N+
Sbjct: 7009 VTE---------LEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNN 7059

Query: 430  RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489
                                L+   V ++DSG  TC A N  G  + +    + E++  +
Sbjct: 7060 VA-----------------TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ--L 7100

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
             P F  +   +    G PV L  R  G+   ++ W +DGV +  +  L+       +TL 
Sbjct: 7101 PPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLK 7160

Query: 550  IPRAKASDAAWYQCTAQNVAGSTATRARL 578
            I +   S +  Y C+A N  G+ ++ ARL
Sbjct: 7161 ILQTDLSHSGQYSCSASNPLGTASSSARL 7189



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 60/189 (31%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F +  Q   V EG    F+  ++G P PEV+WF + + I       + ++ S   A 
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I  VT ++SG  +  A N SG+      L V  K +   P FV+R  ++ VR+G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV--KAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L  R  G PTP + + +DG  I  + + +I  +G   +L I  A   D+  Y   A N  
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182

Query: 570 GSTATRARL 578
           G   + A L
Sbjct: 183 GRATSTAEL 191



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 109/493 (22%), Positives = 178/493 (36%), Gaps = 50/493 (10%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G     E K+ G P   V W +    L    K+   +  +    SL I  +   D G YT
Sbjct: 6645 GETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS--SLRILSVERQDAGTYT 6702

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHV---SETVEHKAYGTQGYTTEQSR 202
               +N  G++ C+  +                    V   S  +E K  G+   +     
Sbjct: 6703 FQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFH 6762

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262
            +  K+   +G  + +T    V T +   L + S   + T      ++V  S E    L  
Sbjct: 6763 EKTKIV--SGAKYQTTFSDNVCTLQLNSL-DSSDMGNYT---CVAANVAGSDECRAVLTV 6816

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
              PP   ++P   ++  G +  F   + G P  +V WF+  + L+  ++  I        
Sbjct: 6817 QEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 6876

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L + N   S SG YT        C+V++                      +  Q     R
Sbjct: 6877 LELFNIDISQSGEYT--------CVVSN----------------------NAGQASCTTR 6906

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + + E A    F+K   D  V  GK    +   TG     VTW  +   I       I+ 
Sbjct: 6907 LFVKEPAA---FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVT 6963

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
             E     L I N T  D+G  +C   N++G       ++ +E      P FV     L  
Sbjct: 6964 TEK-TCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEP-----PYFVTELEPLEA 7017

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              G+ V L  +  GTP   ++W K    + P PE R +     +TL   +   +D+  Y 
Sbjct: 7018 AVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYT 7077

Query: 563  CTAQNVAGSTATR 575
            C A+N  G+ +++
Sbjct: 7078 CKAENSIGTASSK 7090



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 105/446 (23%), Positives = 183/446 (41%), Gaps = 47/446 (10%)

Query: 54   SSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLV 113
            SS  R  +T G+    +PP F+          G +A FE  + G     VSW +    + 
Sbjct: 9066 SSSARLILTEGK----NPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIR 9121

Query: 114  ECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXX 173
               KY + Y E +  +++L  ++  GD G+YTC A N+ G+  C+  +  +         
Sbjct: 9122 SGGKYQISYLENSAHLTVL--KVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT 9179

Query: 174  XXXXXYRHVSETVEH---KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL 230
                  + +SETVE     ++  +G     S+      Y N  +   T + ++ TF+   
Sbjct: 9180 ------KRLSETVEETEGNSFKLEG-RVAGSQPITVAWYKNNIEIQPTSNCEI-TFKNNT 9231

Query: 231  L----REVSFRES--ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQ 284
            L    R+    ++   T +   ++   + T       P  PP   Q      + EG   Q
Sbjct: 9232 LVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQ 9291

Query: 285  FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPN 344
                + G+   R+ W K G+ +  S++           L +R+  K+DSG Y   A N  
Sbjct: 9292 LSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVA 9351

Query: 345  GCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI-EISEKALAPQFVKVCQDRDV 403
            G   T   + ++          +      T++   + R+  +SE    PQ ++V +    
Sbjct: 9352 GSDTTKSKVTIK---------DKPAVAPATKKAAVDGRLFFVSE----PQSIRVVEKTTA 9398

Query: 404  TEGKMTRFDCRVTGRPYPEVTWFIND-RQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
            T      F  +V G P P V W     RQ+  +   ++ +++ G+ A L I + T +DSG
Sbjct: 9399 T------FIAKVGGDPIPNVKWTKGKWRQL--NQGGRVFIHQKGDEAKLEIRDTTKTDSG 9450

Query: 462  VVTCVARNKSGETAFQCRLNVIEKEQ 487
            +  CVA N+ GE      L V E+++
Sbjct: 9451 LYRCVAFNEHGEIESNVNLQVDERKK 9476



 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 96/405 (23%), Positives = 174/405 (42%), Gaps = 52/405 (12%)

Query: 4413  FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
             F + +   +V E E ARFE E   E    +KW+++   IK    + I +     IL+I +
Sbjct: 13303 FLRPLTDLQVREKEMARFECELSRENAK-VKWFKDGAEIKKGKKYDIISKGAVRILVINK 13361

Query: 4473  VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
               ++D A ++        TA+ S  L V E+            FT    N+ V+    ++
Sbjct: 13362 CLLDDEAEYSCEVR----TARTSGMLTVLEEEAV---------FTKNLANIEVSETDTIK 13408

Query: 4533  LDTKVTGTKP-IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
             L  +V+  KP  +V W K  +++    R +IL E     L+I  A+ +D+G Y C     
Sbjct: 13409 LVCEVS--KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC----- 13461

Query: 4592  AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
                          LP+++   K   K      E I   ++  + EG+  EF C I  +  
Sbjct: 13462 ------------RLPSSRTDGK--VKVHELAAEFISKPQNLEILEGEKAEFVCSISKESF 13507

Query: 4652  PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV--AYNSAGRVTVAAK 4709
             P VQW + DK ++    + +     +  L + +A  +D G Y  +  A  +A  +TV  K
Sbjct: 13508 P-VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEK 13566

Query: 4710  LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
             L++           + PL+D  V E Q   F  ++ ++     +W R    I ++  + +
Sbjct: 13567 LRI-----------VVPLKDTRVKEQQEVVFNCEVNTE-GAKAKWFRNEEAIFDSSKYII 13614

Query: 4770  IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVVKSK 4813
             + +     L I + + +D   +    T   G+ V+++A L+V+ +
Sbjct: 13615 LQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEE 13659



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 66/243 (27%), Positives = 108/243 (44%), Gaps = 10/243 (4%)

Query: 241  TKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF 300
            T   + ES V  ST+ D       P  I ++  N+ +  G  A   V + G P+P++ WF
Sbjct: 3480 TLELLSESPVY-STKFDSEKEGTGPIFI-KEVSNADISMGDVATLSVTVIGIPKPKIQWF 3537

Query: 301  KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             NG  L  S  ++ +   +  +L +  T+  D G YT +A N  G  + S YL + S  E
Sbjct: 3538 FNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3597

Query: 361  SYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPY 420
             +         T+T+     + +E       P F+K  +     +G    F+  V G P 
Sbjct: 3598 GHKD-------TETES-AVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPA 3649

Query: 421  PEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            P VTWF  ++Q+     + I+ N +G+   ++ +    DSG+  C A N  GE+     L
Sbjct: 3650 PTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 3709

Query: 481  NVI 483
             V+
Sbjct: 3710 LVL 3712



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 105/404 (25%), Positives = 168/404 (41%), Gaps = 44/404 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P + T  ++     E +   FEV  + E +   KW +    IK++   Q+ T      L 
Sbjct: 2968 PIMITSMLKDINAEEKDTITFEVTVNYEGISY-KWLKNGVEIKSTDKCQMRTKKLTHSLN 3026

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            IR V   D+A +  VA    G A  +A L VE +  + R  I         +++ V   +
Sbjct: 3027 IRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHI---------KDIKVLEKK 3073

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
                + +V+    I V W+K+ +++Q   R KI +E   + LLI      D+GKY  VA 
Sbjct: 3074 RAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAG 3132

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
             +   A+   E        +D    + ++     ++IE  K + V     +EF    V +
Sbjct: 3133 GNVSTAKLFVE-------GRD---VRIRSIKKEVQVIE--KQRAV-----VEFE---VNE 3172

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                  WYK    I      +     +   + + ISE    D G+Y  V    AGR   +
Sbjct: 3173 DDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV----AGRNRSS 3228

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              L V  P+    L  L P   + V  G+PA+F   I+ + +P I W +E  L+      
Sbjct: 3229 VTLYVNAPEPPQVLQELQP---VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3285

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + +H+G    LL+   + ED   +TC A    G   TSA L V+
Sbjct: 3286 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 111/512 (21%), Positives = 200/512 (39%), Gaps = 53/512 (10%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F+    +   A G +  F+  + G     ++W +    +     Y M   E T  ++
Sbjct: 8138 PPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLT 8197

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            +L  ++G GD G+YTC A N  G+  CS ++  +                  S  V+   
Sbjct: 8198 VL--KVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPPRFIKKL-------EPSRIVKQDE 8248

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFK---VDTFEYRLLREVSFRESITKRYVGE 247
            +         S + + + Y + T+   +  F+   VD+     +  +S  +S    Y  E
Sbjct: 8249 FTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDS--GDYTCE 8306

Query: 248  S-DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
            + +   S     SL    PP   +KP   +  +GAD   + +L G P   V+W+K+ + L
Sbjct: 8307 AHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKREL 8366

Query: 307  INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ 366
             +  K++I++ +  T++ + N   +D G Y   A N  G     G +A+++P   +V+  
Sbjct: 8367 RSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPR-FVKKL 8425

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
                    ++ + +  IE +E       + V   +D  +G++ R    +         W 
Sbjct: 8426 SDISTVVGKEVQLQTTIEGAEP------ISVVWFKD--KGEIVRESDNI---------WI 8468

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
                 I      ++    +G +   I N    D+G+  C A            L+V+E  
Sbjct: 8469 SYSENIATLQFSRVEPANAGKYTCQIKN----DAGMQECFA-----------TLSVLEPA 8513

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
             +V     E+  ++ V  G+   L     GTP     W KDG  +  + + +I      S
Sbjct: 8514 TIV-----EKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS 8568

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             L I     SD+  Y    QN  G  +  A L
Sbjct: 8569 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASL 8600



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 4/171 (2%)

Query: 402  DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
            D   G+   F+C VTG    +V+W  + R+IR    ++I   E+  H L +  V   DSG
Sbjct: 9090 DAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAH-LTVLKVDKGDSG 9148

Query: 462  VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTP 520
              TC A N+ G+ +   +LN+  KE+++ P F +R S T+   EG    L  R  G+   
Sbjct: 9149 QYTCYAVNEVGKDSCTAQLNI--KERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPI 9206

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             + W K+ + I P     I        L + +A  +DA  Y C   N AGS
Sbjct: 9207 TVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGS 9257



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)

Query: 382  RIEISEKALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            ++ I E+ + P F K + +  + TEG   + + RV G     V W+ N+ +I+   N +I
Sbjct: 9166 QLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEI 9225

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
               ++    L +    ++D+G+ TC   N +G     C  +++ KE    P F +  + +
Sbjct: 9226 TF-KNNTLVLQVRKAGMNDAGLYTCKVSNDAGSAL--CTSSIVIKEPKKPPVFDQHLTPV 9282

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             V EGE V L+    G+   RI W K G  I P+         G + L++     +D+  
Sbjct: 9283 TVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGD 9342

Query: 561  YQCTAQNVAGSTATRARL 578
            Y C A NVAGS  T++++
Sbjct: 9343 YVCKASNVAGSDTTKSKV 9360



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 102/400 (25%), Positives = 157/400 (39%), Gaps = 48/400 (12%)

Query: 3546 DTLTPEAESG-NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            + ++P+ E    PP   T   D + SE   A F+CR   V+ + ++V W+   K +   S
Sbjct: 3332 EVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP-S 3387

Query: 3605 RVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILE----- 3658
            R   +  F     LEI   Y  D G YT  A+N  G+ + +  L ++  + I+ E     
Sbjct: 3388 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447

Query: 3659 -----PQLPSHFKSGTES--------IQKLEETLHKREEITI-----EDEKPNPPRFTVE 3700
                  +  S F S  E         + K+ ETL    E  +     + EK       ++
Sbjct: 3448 IEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIK 3507

Query: 3701 IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYI 3760
               N D+  G        V  +G P  +I WF NG      +    + D    +L I + 
Sbjct: 3508 EVSNADISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFT 3565

Query: 3761 YARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAP 3820
               D GEYTC A+N +G      K  CSA   I           GE  K+ E        
Sbjct: 3566 KLEDEGEYTCMASNDYG------KTICSAYLKI--------NSKGEGHKDTETESAVAKS 3611

Query: 3821 KEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
             E+     PP F+ ++K     +     FE  V  +  P   + W++  K L +   Y  
Sbjct: 3612 LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPT--VTWFKENKQLCTSVYYTI 3669

Query: 3881 VYDM-GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            +++  G  +  +     EDSG YIC+A N  GE    A +
Sbjct: 3670 IHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 3709



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/224 (29%), Positives = 98/224 (43%), Gaps = 12/224 (5%)

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDF 4457
            E   E  ++    P+F  K    +  E + ARF+++  G P+P   W+ +   I N    
Sbjct: 1444 EETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTH 1503

Query: 4458 Q--IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
            +  I    T+S++I+      DS  +  VA+NR G +  S  L VE    Q     V P 
Sbjct: 1504 KVVIKEDGTQSLIIV-PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQ-----VKPM 1557

Query: 4516 FTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLI 4573
            F    +NVN+  G  + +  + TG    D+ WLKN   + P    KI  E   G   L I
Sbjct: 1558 FVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKI 1617

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                 QDS  Y   AIN AG  R    C V++     +P+P+ K
Sbjct: 1618 DSTVSQDSAWYTATAINKAG--RDTTRCKVNVEVEFAEPEPERK 1659



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 63/227 (27%), Positives = 100/227 (44%), Gaps = 8/227 (3%)

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            L + SP  S       Q   D   RE    + + E A   + ++  +   VT G     +
Sbjct: 7536 LQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPA---RIIEKPEPMTVTTGNPFALE 7592

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C VTG P     WF + R++  D  H I  +N+  +  L I    +SD G+ +   +N  
Sbjct: 7593 CVVTGTPELSAKWFKDGRELSADSKHHITFINKVAS--LKIPCAEMSDKGLYSFEVKNSV 7650

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G++   C ++V   +++V P F+ +   +N   G  VVL  R  G+    + W +DG  I
Sbjct: 7651 GKS--NCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEI 7708

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +  P+ +        TL++   + SD   Y C A NVAGS    A L
Sbjct: 7709 VSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 7755



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 100/399 (25%), Positives = 173/399 (43%), Gaps = 43/399 (10%)

Query: 4417  MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
             ++  RV E ++  F  E + E     KW+R    I +S  + I        L IR   ++
Sbjct: 13573 LKDTRVKEQQEVVFNCEVNTEGAKA-KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 13631

Query: 4477  DSAVF-AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
             D A +  ++  +RG   K +ANL+VEE+  +    IV P      +++     + V    
Sbjct: 13632 DQANYNVSLTNHRGENVKSAANLIVEEEDLR----IVEP-----LKDIETMEKKSVTFWC 13682

Query: 4536  KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
             KV     + + W KNG++V  D R     +   + L I +    D G+Y    I +AG+ 
Sbjct: 13683 KVNRLN-VTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEY----IVTAGQD 13737

Query: 4596  RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
             +  AE ++                 AP E +E L+D+ V E     FSC++  +    V+
Sbjct: 13738 KSVAELLI---------------IEAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVK 13781

Query: 4656  WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
             WY+  + IK  K ++  +    + L I +   +DE +Y C   +   R    A+L V + 
Sbjct: 13782 WYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSR----ARLFVEEI 13837

Query: 4716  DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                  +  + P +DI+   G    F  ++ +K K  +QWLR   ++ +    QM+ EG  
Sbjct: 13838 P----VEIIRPPQDILEAPGADVVFLAEL-NKDKVEVQWLRNNMVVVQGDKHQMMSEGKI 13892

Query: 4776  AVLLIGNTYEEDTG--TFTCRATTAAGQVETSAKLVVKS 4812
               L I +    D G   F  +   A  ++E +A   +K+
Sbjct: 13893 HRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKT 13931



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 61/214 (28%), Positives = 96/214 (44%), Gaps = 12/214 (5%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P F     N +++ G +  L   V G     + W  NG  + P    K + +   ++L+I
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA----------PP 4623
            L    +D G+Y C+A N  G+  C A   ++      K   +T++A A          PP
Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK-DTETESAVAKSLEKLGGPCPP 3621

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRI 4682
              ++ LK    A+G    F   +VG+P PTV W+K +K +  S Y+ +    +   T  +
Sbjct: 3622 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 3681

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            ++   ED G Y C A N  G  T AA+L V   D
Sbjct: 3682 NDPQREDSGLYICKAENMLGESTCAAELLVLLED 3715



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 129/538 (23%), Positives = 213/538 (39%), Gaps = 93/538 (17%)

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            ++T    +  PP+       + +     A F C +I       ++ W+   + L TG + 
Sbjct: 3228 SVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQP-KISWYKEEQLLSTGFKC 3285

Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            K ++D     L +   +  DA +YTC+A N +G AT S  L V+  + +  + ++P +  
Sbjct: 3286 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVY-- 3343

Query: 3667 SGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT 3726
                 I  L++T      +T E +   P RF                   CR   V    
Sbjct: 3344 -PPAIITPLQDT------VTSEGQ---PARF------------------QCR---VSGTD 3372

Query: 3727 MRIDWFHNGRPFATGSRVHTLNDF-GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +++ W+   +     SR   +  F     L+I   Y  D G YT  A+N  G  ++TA +
Sbjct: 3373 LKVSWYSKDKKIKP-SRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3431

Query: 3786 TCSAKRDIV---LESQLPQGM------------SGEKIKELERGRISDAPK---EEPIVS 3827
            +  A   I+   +E ++   M             G    EL+  +I++  +   E P+ S
Sbjct: 3432 SLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYS 3491

Query: 3828 TP---------PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878
            T          P FI ++ +  +  S G      V     PK +I+W+ NG LL     Y
Sbjct: 3492 TKFDSEKEGTGPIFIKEVSNADI--SMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADY 3549

Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938
            + V+D    SL IL+   ED GEY C A ND+G+    A +           N    G K
Sbjct: 3550 KFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI---------NSKGEGHK 3600

Query: 3939 RSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLA 3998
             +E  + +  +++K                   PP F+ +++       +    FE  + 
Sbjct: 3601 DTETESAVAKSLEKLGGPC--------------PPHFLKELKPIRCAQGLPAI-FEYTV- 3644

Query: 3999 PVGDPNMKVEWFFNGKPLLHKNRFTPIYD-FGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             VG+P   V WF   K L     +T I++  G           EDSG Y+C+A N+ G
Sbjct: 3645 -VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG 3701



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 79/297 (26%), Positives = 132/297 (44%), Gaps = 23/297 (7%)

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITV-MQAPQFSRALHNIETVEGTNVHLECR 1333
            I   T  E+  E +   E     T +V   + + +  P     L N+  +EG +V LEC 
Sbjct: 906  ITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECH 965

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            +   G  +  V W+     I++   F+  ++     L +   + EDSG +TC A N+ G 
Sbjct: 966  IS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023

Query: 1394 AVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII--DESVT---------I 1442
              TSC L V   ++   E +  +  EK    E+    +  D++  D S+T          
Sbjct: 1024 VSTSCYLAVQVSEE--FEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLTEEQAGPGEPA 1080

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD--FG 1500
             P F+T+P  ++ ++EG  V F C++    +    V W K+G P+T G+R++  ++   G
Sbjct: 1081 APYFITKP-VVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1137

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
               L I    A+D+G YT    N  G    S  L   +  +++  +Q E  L Q QV
Sbjct: 1138 ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEM-LYQTQV 1193



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 110/510 (21%), Positives = 202/510 (39%), Gaps = 48/510 (9%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  K+     G +   E ++ G+    V W +    +V   K    ++E    ++
Sbjct: 7667 PPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLN 7726

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L + +  P D G YTC A N  G   CS  +  +                 +S T     
Sbjct: 7727 LSLLE--PSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVI 7784

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF--KVDTFEYRLLREVSFRESITKRYVGES 248
             GT  +  +  + ++++     + + S +DF  +++ FE + L    +   +T      +
Sbjct: 7785 RGTPPFKVKWFKGSRELV-PGESCNISLEDFVTELELFEVQPLESGDYSCLVT------N 7837

Query: 249  DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
            D   S      L    P    ++  +  ++ G+    +   +G P   V+W K+ + LI+
Sbjct: 7838 DAG-SASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKD-EYLIS 7895

Query: 309  SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
             ++   IT           T+KS     T+L               +ES  E Y Q    
Sbjct: 7896 QSERCSITM----------TEKS-----TILE-------------ILESTIEDYAQ-YSC 7926

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
                +  Q   E  + + E    P F++  +  +   G+     C+V G P   ++W+  
Sbjct: 7927 LIENEAGQDICEALVSVLEP---PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKE 7983

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
              ++R    +K+   ++   +L+I  V  SD G  +C A N  G  A    L +  KE+ 
Sbjct: 7984 HTKLRSAPAYKMQF-KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI--KERK 8040

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            + P F  +   ++   G PV    R  G+   +++W KDGV +  +  L+       +TL
Sbjct: 8041 LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATL 8100

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I +   S    Y C+A N  G+ ++ A+L
Sbjct: 8101 QILQTDQSHIGQYNCSASNPLGTASSSAKL 8130



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 77/263 (29%), Positives = 112/263 (42%), Gaps = 19/263 (7%)

Query: 1699 RHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            R  A  E+    P     +K++ V E ++   E  +   G P   V W R    IE+S  
Sbjct: 931  RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSID 988

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
                   G   L ++    EDSG +TC A+NE G   TS  L VQ   S + E +  +  
Sbjct: 989  FQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--VSEEFEKETTAVT 1046

Query: 1819 QKIQQLED---SSRYQRREDVEVAVNQ-------APRFITQLNGPTKLSEGQSAHYECRI 1868
            +K    E     SR     D  +   Q       AP FIT+     KL EG S  + C++
Sbjct: 1047 EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQV 1105

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTS--NDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
               P P+  V W  +G  L +G+RY+ S     G   L I   + +D+GEYT    N  G
Sbjct: 1106 GGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1163

Query: 1927 QAVSSIRLNVQSKESIIRDSQHE 1949
            +  +S  L  ++   ++  SQ E
Sbjct: 1164 ETSASASLLEEADYELLMKSQQE 1186



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 91/384 (23%), Positives = 165/384 (42%), Gaps = 44/384 (11%)

Query: 4415  KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
             + +    V E E ARFE E   + +    W  +   +  +PD +I        L++    
Sbjct: 13038 RPLHSVEVMETETARFETEISEDDIHA-NWKLKGEALLQTPDCEIKEEGKIHSLVLHNCR 13096

Query: 4475  VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
             ++ +      A N     K SA+L V+ +      G++ P      ++V VT+G+    D
Sbjct: 13097 LDQTGGVDFQAAN----VKSSAHLRVKPRVI----GLLRP-----LKDVTVTAGETATFD 13143

Query: 4535  TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
              +++  + I V W   GKK++P  +     E   +TL + +   +D+G+ +     +A +
Sbjct: 13144 CELS-YEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQL----TAKD 13198

Query: 4595  ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
              +  A   V  P               P E  +PL+D+ V EG      C+ V +    V
Sbjct: 13199 FKTHANLFVKEP---------------PVEFTKPLEDQTVEEGATAVLECE-VSRENAKV 13242

Query: 4655  QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
             +W+K    I  SK +++        L I +  PED   Y C A +       +  L V  
Sbjct: 13243 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKD----FKTSCNLNVVP 13298

Query: 4715  PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
             P    ++  L PL D+ V E + A+F+ ++ S+    ++W ++GA I +   + +I +G 
Sbjct: 13299 P----HVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGA 13353

Query: 4775  NAVLLIGNTYEEDTGTFTCRATTA 4798
               +L+I     +D   ++C   TA
Sbjct: 13354 VRILVINKCLLDDEAEYSCEVRTA 13377



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 116/517 (22%), Positives = 208/517 (40%), Gaps = 48/517 (9%)

Query: 4307 DKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQK 4366
            D+    T  K + +         E+V E+  + +   K R  +     +   E+   K+ 
Sbjct: 1965 DRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKD 2024

Query: 4367 QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPV-KPSK---------PPIFTKK 4416
            ++ +E++   +      + E TE E KA  +E  +  P  KP K         P IF ++
Sbjct: 2025 ESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIF-ER 2083

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSILIIRQVFV 4475
            +Q   V +   A F V   G+P P  +WY+    I+ S   +          L+IR V  
Sbjct: 2084 IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTA 2143

Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            EDSA     A N  G     A L+V+ K+      ++  +FT   Q+V       +    
Sbjct: 2144 EDSASIMVKAINIAGETSSHAFLLVQAKQ------LI--TFTQELQDVVAKEKDTMATFE 2195

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T    + V W K+G +V    + ++  +   + L IL     D+  Y CV +      
Sbjct: 2196 CETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NV 2254

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
            +  A+ +V                 A  E ++ L+D  V E  + E  C IV       +
Sbjct: 2255 KTTAKLIVE---------------GAVVEFVKELQDIEVPESYSGELEC-IVSPENIEGK 2298

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            WY  D  +K +  + ++       L + +   ED+G+Y  V      + T   K+K  +P
Sbjct: 2299 WYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMK-PRP 2355

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                 +  L  L D  V EG   Q + +++ +    + W+++G  +  +    ++ +  +
Sbjct: 2356 -----IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQS 2409

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +LLI +  +ED G ++   T  A  + TS ++ V S
Sbjct: 2410 HMLLIEDMTKEDAGNYS--FTIPALGLSTSGRVSVYS 2444



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 73/261 (27%), Positives = 114/261 (43%), Gaps = 14/261 (5%)

Query: 3803 MSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            + G + K  E  R+  AP E P+  TPP  ++ +K+ TV E E V  EC +     P   
Sbjct: 919  LHGREAKVTETARVP-APVEIPV--TPPTLVSGLKNVTVIEGESVTLECHISGYPSPT-- 973

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            + WYR    + S   ++  +  G   L I   +AEDSG + C AVN+ G   T   ++ +
Sbjct: 974  VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033

Query: 3923 KLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQ 3982
               +   +         +E    +E+     T +  LTE+      +   P F+T+   Q
Sbjct: 1034 VSEEFEKETTAVTEKFTTEEKRFVESRDVVMT-DTSLTEEQA-GPGEPAAPYFITKPVVQ 1091

Query: 3983 TSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD--FGYVAMNFGWVYP 4040
              LVE  +  F CQ+   G+P   V W  +G PL    R+   Y+   G   +     + 
Sbjct: 1092 -KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFA 1148

Query: 4041 EDSGEYLCRATNLYGMDETKA 4061
            +D+GEY     N +G  ET A
Sbjct: 1149 DDAGEYTIVVRNKHG--ETSA 1167



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 22/283 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            VE+ V   P  ++ L   T + EG+S   EC I  YP P   V WY     ++S   ++ 
Sbjct: 936  VEIPVTP-PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQI 991

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            +   G A L I   + EDSG +TC A+N  G   +S  L VQ  E    + +  +  EK 
Sbjct: 992  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF--EKETTAVTEK- 1048

Query: 1956 QYLEDDSRYKRA----VQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPV------N 2005
             +  ++ R+  +    + D S   E+   G+P     +T+     L    + V       
Sbjct: 1049 -FTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1107

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYD--FGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            +P   V W  +G P+  G+R+K +Y+   G   L I   +A+D G Y     N  GE   
Sbjct: 1108 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSA 1167

Query: 2064 TSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPG 2106
            ++S+  +A   L + +  ++ L + Q     + PK + E  PG
Sbjct: 1168 SASLLEEADYELLMKS-QQEMLYQTQVTAFVQEPK-VGETAPG 1208



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 57/207 (27%), Positives = 95/207 (45%), Gaps = 6/207 (2%)

Query: 373  DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
            D  +   + RI + +  + P F K  +  D  +G     +C V G     + WF +D++I
Sbjct: 5583 DVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEI 5642

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPK 492
                 +K   +++    L I+ +  +DSG  TC A NK+G    QC  ++  KE    P 
Sbjct: 5643 SASEKYKFSFHDN-TAFLEISQLEGTDSGTYTCSATNKAGHN--QCSGHLTVKEP---PY 5696

Query: 493  FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552
            FVE+  + +V     V L A   GT    I W KD   +       +  D  +++L++  
Sbjct: 5697 FVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFA 5756

Query: 553  AKASDAAWYQCTAQNVAGSTATRARLY 579
            AKA+D+  Y C   N  G+  ++A L+
Sbjct: 5757 AKATDSGTYICQLSNDVGTATSKATLF 5783



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 89/379 (23%), Positives = 159/379 (41%), Gaps = 28/379 (7%)

Query: 4360 VHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQP 4419
            V V+++ + +   V +K  T +    E+ ++     +      GP +P+ P   TK +  
Sbjct: 1032 VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQ 1091

Query: 4420 CRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSILIIRQVFVED 4477
             ++ E     F  +  G P P + W +   P+     +++  +  + +  L+I   F +D
Sbjct: 1092 -KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADD 1150

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            +  +  V  N+ G    SA+L+ E         ++  S         VT+   V+ + KV
Sbjct: 1151 AGEYTIVVRNKHGETSASASLLEEADYE-----LLMKSQQEMLYQTQVTA--FVQ-EPKV 1202

Query: 4538 TGTKPIDVY--WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T P  VY  + K  +K Q  IR K+ ++      +++  Y +D  ++   +       
Sbjct: 1203 GETAPGFVYSEYEKEYEKEQALIRKKMAKDT-----VVVRTYVEDQ-EFHISSFEERLIK 1256

Query: 4596 RCDAECV-VSLPATKDKPKPQTKAAN-APPEIIEP-----LKDKIVAEGQAIEFSCKIVG 4648
              +   +  +L    ++   +  A + +  E +E      +K+  + EG  + F CK+ G
Sbjct: 1257 EIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSG 1316

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             PLP + WYK  K IK  + +QM    D   +LRI    PEDEG Y   A N  G    +
Sbjct: 1317 YPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICS 1376

Query: 4708 AKLKVTQPDQADNLPALTP 4726
             KL V +P      P   P
Sbjct: 1377 GKLYV-EPAAPLGAPTYIP 1394



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 67/227 (29%), Positives = 98/227 (43%), Gaps = 7/227 (3%)

Query: 4315 AKSMAQRYEDNLDQ-TEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVV 4373
            A S AQ+   ++   T + +E RV+ + T  P+ P       +  E  V  +K+    + 
Sbjct: 848  ATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSIT 907

Query: 4374 GDKEITRKITSTETTEIEHKAQTQERVVEGPVK-PSKPPIFTKKMQPCRVFEHEQARFEV 4432
            G    T +    E         T+   V  PV+ P  PP     ++   V E E    E 
Sbjct: 908  GT---TVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
               G P P + WYRE++ I++S DFQI   S  + L+IR+ F EDS  F   A N  GT 
Sbjct: 965  HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 1024

Query: 4493 KCSANLVVE-EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
              S  L V+  +  +     V   FT T +   V S  +V  DT +T
Sbjct: 1025 STSCYLAVQVSEEFEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLT 1070



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 130/523 (24%), Positives = 202/523 (38%), Gaps = 72/523 (13%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PPQ +  L+ VT   G    F   I   G P  KI W K  Q +    +   +      +
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L ++    +D+  YTC A +  GVA T A L V          + PE +   Q++  Y  
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQEMPVYP- 3344

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                          P  I PLQD     EG+ A F+ +   VS   ++V WY   + I  
Sbjct: 3345 --------------PAIITPLQDT-VTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 3386

Query: 816  SS--RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV---TA 870
            S   R+T  F   Y  L I     ED G+YT  A N +G+  STA++ + A  ++     
Sbjct: 3387 SRFFRMTQ-FEDTY-QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3444

Query: 871  DLGIP-EQRRYIEKTXXXXXXXXXXXXXXXXXVPES----TQKPEFKTPIKDQ------I 919
            +  I  E + +                     + E+    ++ P + T    +      I
Sbjct: 3445 EQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPI 3504

Query: 920  SIKEGGFAHFE------ARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKS 973
             IKE   A           +  IG    +++W  +G  +  S+     F+    +L I  
Sbjct: 3505 FIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF 3564

Query: 974  VTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRT 1033
              + D G YTC A N  G+   SA L I +K +   +++    + K             +
Sbjct: 3565 TKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK-------------S 3611

Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI-TSANRI 1092
             E++     P FL  LK   +  +G  A FE  V    +   TV W+   KQ+ TS    
Sbjct: 3612 LEKLGGPCPPHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYT 3668

Query: 1093 QTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              ++  G     +   + EDSG+Y   A N  GE+  +A + V
Sbjct: 3669 IIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3711



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 97/427 (22%), Positives = 171/427 (40%), Gaps = 49/427 (11%)

Query: 4387  TTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
             T E+  +A   +      VK   P IF   +   +VFE ++A+FE E   EP    +W +
Sbjct: 12744 TGEVSFQAANAKSAANLKVK-ELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLK 12801

Query: 4447  ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
                 I     F++    TK  ++I+    ED A +   AE++  + K    L++E  R +
Sbjct: 12802 GTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGK----LIIEGIRLK 12857

Query: 4507  GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
                      F    ++V     +      +++    I V W KN +++       + +E 
Sbjct: 12858 ---------FLTPLKDVTAKEKESAVFTVELSHDN-IRVKWFKNDQRLHTTRSVSMQDEG 12907

Query: 4567  GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
              T+++   +    D+ +    A+  + EA+                          P   
Sbjct: 12908 KTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTV-------------------LEGDPYFT 12948

Query: 4627  EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
               L+D    E   +   C+I     P V+W+K  K IKPSK   +     +  L + +A 
Sbjct: 12949 GKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKAL 13007

Query: 4687  PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
               D G Y C      G    + KL +   +    +  + PL  + V E + A+F+T+I S
Sbjct: 13008 KSDIGQYTC----DCGTDKTSGKLDIEDRE----IKLVRPLHSVEVMETETARFETEI-S 13058

Query: 4747  KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
             +      W  +G  + +TPD ++  EG    L++ N   + TG    +    A  V++SA
Sbjct: 13059 EDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQ----AANVKSSA 13114

Query: 4807  KLVVKSK 4813
              L VK +
Sbjct: 13115 HLRVKPR 13121



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 70/302 (23%), Positives = 126/302 (41%), Gaps = 12/302 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  ++    +GG A F+  L+G+    V+W +    + E +   M +       S
Sbjct: 5412 PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVA--S 5469

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L +  I    +G+Y C A+N  G   CS  +  +               +    T++ K 
Sbjct: 5470 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKF 5529

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDD---FKVDTFEYRLLREVSFRESITKRYVGE 247
             GT+  T +  +  Q++   +    S TD     K+ + E +   E +F     +  VG 
Sbjct: 5530 SGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFE---VQNDVGR 5586

Query: 248  SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307
            S  +    +   L  + PP   +K +     +G+    +  ++G+    + WFK+ Q + 
Sbjct: 5587 SSCKARINV---LDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEIS 5643

Query: 308  NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
             S K++     N   L +   + +DSG YT  A N  G    SG+L V+ P   +V+  +
Sbjct: 5644 ASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEP-PYFVEKPQ 5702

Query: 368  SQ 369
            SQ
Sbjct: 5703 SQ 5704



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 80/333 (24%), Positives = 142/333 (42%), Gaps = 33/333 (9%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP FT    + V+ +EG     E  +   G Q + + W+ N   I+ +      +    +
Sbjct: 9175 PPSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTL 9232

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            VL++      D+G Y+C+ +N  G A  +  +  V K   + P F  H+  +  + +G+ 
Sbjct: 9233 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSI--VIKEPKKPPVFDQHLTPVT-VSEGEY 9289

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P ++I+W   G+ ++ S R       G  VL++      DSG+YVC+A
Sbjct: 9290 VQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKA 9347

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
             N  G D T++ +    K  V          A   +  ++ G               F++
Sbjct: 9348 SNVAGSDTTKSKVTIKDKPAV----------APATKKAAVDGRL------------FFVS 9385

Query: 3287 QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY-NGKKLPHGHRYRTFHDFGIVILDIL 3345
            + Q + ++VE  +A F A++    DP   V+W     ++L  G R           L+I 
Sbjct: 9386 EPQSI-RVVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIR 9442

Query: 3346 YCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
               + +SG Y CVA N+ G   +  NL+   ++
Sbjct: 9443 DTTKTDSGLYRCVAFNEHGEIESNVNLQVDERK 9475



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 71/236 (30%), Positives = 106/236 (44%), Gaps = 17/236 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP  +  LK+VT +EG  +  E  I   G P+  + W +    IE+S  F   F+ G   
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIAR 999

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIER-TSQHPE--TLQYIQQLED 752
            L +     +DSG +TC AV+  G   T   L V      E+ T+   E  T +  + +E 
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059

Query: 753  YSKYQHQESIEEQTS-----QRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
                    S+ E+ +       P FI +P+  + +L EG +  F  Q+    +P   V W
Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVEGGSVVFGCQVG--GNPKPHVYW 1115

Query: 807  YKDGRPITASSRITSIFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
             K G P+T   R    +N   G   L I    A+DAG YT+   NK GE  ++AS+
Sbjct: 1116 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 52/206 (25%), Positives = 97/206 (47%), Gaps = 4/206 (1%)

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSK 4667
            ++  + Q +    P  +++P+  K + EGQ   F  K+VG+P+P   W+  G +++    
Sbjct: 1444 EETDESQLERLYKPVFVLKPVSFKCL-EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYT 1502

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +  + +     +L I  A P D G++  VA N AGR +++  L V   +       +  L
Sbjct: 1503 HKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKL 1562

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI--PETPDFQMIHEGNNAVLLIGNTYE 4785
            +++ + EG   + K + T    P I WL+   +I   + P  ++      A L I +T  
Sbjct: 1563 KNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVS 1622

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            +D+  +T  A   AG+  T  K+ V+
Sbjct: 1623 QDSAWYTATAINKAGRDTTRCKVNVE 1648



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 109/526 (20%), Positives = 194/526 (36%), Gaps = 27/526 (5%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V K+G++I  EC +  S  P +K+ WF N+  L    +Y  +   S   L I     EDS
Sbjct: 7302 VAKQGESIQLECKISGS--PEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDS 7359

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGK-AGLEAVEQAEEARLAKGRRPS 2902
            G Y C+A N  G A+ S +L       ++     P G   G + + Q E +         
Sbjct: 7360 GDYICEAHNGVGDASCSTALTVKAPP-VFTQKPSPVGALKGSDVILQCEISGTPPFEVVW 7418

Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLE----GQVEPKNDPDLKIEWYFNGKVLEQGS 2958
            V D +  +      I ++H      +L+LE    G+   K   ++  +        ++  
Sbjct: 7419 VKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 7478

Query: 2959 RF-KLTSDFGFVTLDLVDVYERDSGIYTCKA--YNKRGEAFTSSTVYCTSKDNLIERTQH 3015
            RF K  SD   +  D V++     G           RGE    S     S  + I   Q 
Sbjct: 7479 RFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQ- 7537

Query: 3016 PKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPT 3075
              G+            ++ + G +         E   + +    ++      +    + T
Sbjct: 7538 -LGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVT 7596

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G   +  +WF +G+ + A  +    +   +  L+I   + +D G YS    N  G++  +
Sbjct: 7597 GTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT 7656

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
            V +   D+     P F   ++++  +  G S   EC V       + + W+ +G  +   
Sbjct: 7657 VSVHVSDRI--VPPSFIRKLKDVNAIL-GASVVLECRV--SGSAPISVGWFQDGNEIVSG 7711

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD 3255
             + ++        L+++  +  D+G Y C A N  G D   A +              PD
Sbjct: 7712 PKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSF---EQTPD 7768

Query: 3256 SLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAH 3301
            S      +E L G      S     PP  +   +   +LV G+S +
Sbjct: 7769 S------VEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCN 7808



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 94/406 (23%), Positives = 173/406 (42%), Gaps = 34/406 (8%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF-PIKNSPDFQIHTFSTKSILIIR 4471
            F  + Q  RV E   A F  +  G+P+P +KW +  +  +       IH    ++ L IR
Sbjct: 9383 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIR 9442

Query: 4472 QVFVEDSAVFAAVAENRGGTAKCSANLVVEE-KRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                 DS ++  VA N  G  + + NL V+E K+++   G +      T   +   +G+ 
Sbjct: 9443 DTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPI-LKKGAGEE 9501

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              +D      K +D    +   ++    D R  +   +     L+ ++  +++ + E   
Sbjct: 9502 EEIDIMEL-LKNVDPKEYEKYARMYGITDFRGLLQAFE-----LLKQSQEEETHRLEIEE 9555

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI-V 4647
            I  +     + E +VS          Q  +   P  +I+ ++++ V +     F   I +
Sbjct: 9556 IERSERDEKEFEELVSFIQ-------QRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKI 9608

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
              P   + WYKG + ++PS  F++S   D +TLR+     +D+G+Y+ V     G    +
Sbjct: 9609 NYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLV----CGPHIAS 9664

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            AKL V +P    +      L+D+ + EGQ      Q  S      +W R G ++      
Sbjct: 9665 AKLTVIEPAWERH------LQDVTLKEGQTCTMTCQF-SVPNVKSEWFRNGRILKPQGRH 9717

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +   E     L I +   ED G +TC+       +ETSA+L ++++
Sbjct: 9718 KTEVEHKVHKLTIADVRAEDQGQYTCKYE----DLETSAELRIEAE 9759



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 87/347 (25%), Positives = 143/347 (41%), Gaps = 29/347 (8%)

Query: 242  KRYVGESDVQIS-TEI-DRSLGPVSP--PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
            KR+V   DV ++ T + +   GP  P  P    KP   KL EG    F  Q+ GNP+P V
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113

Query: 298  TWFKNGQRLINSNKHEIITTHNHTT----LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
             W K+G  L    ++++  ++N  T    L +  T   D+G YT++  N +G    S  L
Sbjct: 1114 YWKKSGVPLTTGYRYKV--SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171

Query: 354  AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
              E+  E  ++ Q+ + +  TQ     +  ++ E   AP FV    +++    K      
Sbjct: 1172 LEEADYELLMKSQQ-EMLYQTQVTAFVQEPKVGE--TAPGFVYSEYEKEYE--KEQALIR 1226

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
            +   +    V  ++ D++       + L+ E       I   TL +          + GE
Sbjct: 1227 KKMAKDTVVVRTYVEDQEFHISSFEERLIKEI---EYRIIKTTLEE-------LLEEDGE 1276

Query: 474  TAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
               +  +++ E E  V   F  R     + EG  V  + +  G P P+I W KDG  I  
Sbjct: 1277 E--KMAVDISESE-AVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKH 1333

Query: 534  NPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
                ++     G ++L IP     D   Y   A N+ G+     +LY
Sbjct: 1334 GERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLY 1380



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 23/262 (8%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP++ Q+ +   +Q G  A+F   +SG P+P+++W+K  Q L    K + +      TL 
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +      D+  YT  A+N  G   TS  L+VE P E    DQ                  
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP-EVVSPDQEM---------------- 3340

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P  +   QD   +EG+  RF CRV+G    +V+W+  D++I+     ++   E
Sbjct: 3341 ---PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFE 3396

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
               + L I      D G  T VA N  G+ +    L++   E ++  + +E+   + ++E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHER-IEQEIEMEMKE 3454

Query: 505  GEPVVLNARAVGTPTPRITWQK 526
                 L+A   G  +  +   K
Sbjct: 3455 FSSSFLSAEEEGLHSAELQLSK 3476



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 100/385 (25%), Positives = 155/385 (40%), Gaps = 60/385 (15%)

Query: 2904 PDTEYPK-PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            PD E P  P  II    +    EGQ    + +V   +  DLK+ WY   K ++    F++
Sbjct: 3336 PDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRM 3392

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLI-ERTQHP----- 3016
            T       L++ + Y  D G YT  A N  G+  +++ +   + ++++ ER +       
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEM 3452

Query: 3017 ---------KGTEGLE-------KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI--V 3058
                        EGL        KI    + L + P      D+ +        K++   
Sbjct: 3453 KEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNA 3512

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            DIS G +A    ++I  G     I+WF+NG  +  S   + V+      L IL TK  D 
Sbjct: 3513 DISMGDVATLSVTVI--GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDE 3570

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQK--------------------PRFTTHIQNI 3158
            G Y+C A+N +G+   S  L+   K +G K                    P F   ++ I
Sbjct: 3571 GEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPI 3630

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS---TRIKTVSDFG-FVVLDIAYT 3214
                 G  A FE TV  V +P   + W+   + +  S   T I   +  G F+V D    
Sbjct: 3631 R-CAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVND---P 3684

Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATI 3239
            Q  DSG Y+C+A N  GE    A +
Sbjct: 3685 QREDSGLYICKAENMLGESTCAAEL 3709



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 76/316 (24%), Positives = 135/316 (42%), Gaps = 41/316 (12%)

Query: 265  PPKIAQKPRNSKLQEGADA-QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            PPK  +K   SK+ +  D+ + + +++G+P  RV WF+        N+HE+         
Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFR--------NEHEL--------- 6391

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                   SD    T +    +  ++    L+ E   +   + Q     T    +   +  
Sbjct: 6392 -----PASDKYRMTFI---DSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP 6443

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
             +      P  V+  ++ +V+       +C ++G P  EV W+ + RQ+R    +KI  +
Sbjct: 6444 PVFSSF--PPIVETLKNAEVS------LECELSGTPPFEVVWYKDKRQLRSSKKYKI-AS 6494

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            ++ + ++ I NV  SD G   C A+N+ G     C + + E      P+FV + ++L V 
Sbjct: 6495 KNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEP-----PRFVSKLNSLTVV 6549

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQ 562
             GEP  L A   G     + W K+   +I   E +RI      +TL   +A+ ++A  Y 
Sbjct: 6550 AGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYI 6609

Query: 563  CTAQNVAGSTATRARL 578
            C  +N  G     A L
Sbjct: 6610 CQIKNDGGMEENMATL 6625



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 50/182 (27%), Positives = 85/182 (46%), Gaps = 9/182 (4%)

Query: 392  PQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHA 449
            P+FVK  +   V  +G+  + +C+++G P  +V+WF ND ++ + + + +  +N      
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVA--L 7348

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I   +  DSG   C A N  G+ +    L V        P F ++ S +   +G  V+
Sbjct: 7349 LTINEASAEDSGDYICEAHNGVGDASCSTALTV-----KAPPVFTQKPSPVGALKGSDVI 7403

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L     GTP   + W KD   +  + + +I +    ++L I   +ASD   Y C A N  
Sbjct: 7404 LQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEV 7463

Query: 570  GS 571
            GS
Sbjct: 7464 GS 7465



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 53/209 (25%), Positives = 97/209 (46%), Gaps = 21/209 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P  I+ + +  ++ G     S  ++G P P +QW+    L+ PS  ++     D+++L I
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-----------TQPDQADNLPAL------- 4724
                 EDEG+Y C+A N  G+   +A LK+           T+   A +L  L       
Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3622

Query: 4725 --TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIG 4781
                L+ I   +G PA F+  +  +  PT+ W +E   +  +  + +IH  N +   ++ 
Sbjct: 3623 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3682

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED+G + C+A    G+   +A+L+V
Sbjct: 3683 DPQREDSGLYICKAENMLGESTCAAELLV 3711



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 61/228 (26%), Positives = 97/228 (42%), Gaps = 12/228 (5%)

Query: 354  AVESPTESYVQDQRS---QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410
            A+   T+  V+D  S   + + D         I I E    P F+K  +  D+  G    
Sbjct: 4720 AILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP---PSFIKTLEPADIVRGTNAL 4776

Query: 411  FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470
              C V+G    E++WF + +QIR    ++ L ++     L I +   +D G   CV  N+
Sbjct: 4777 LQCEVSGTGPFEISWFKDKKQIRSSKKYR-LFSQKSLVCLEIFSFNSADVGEYECVVANE 4835

Query: 471  SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530
             G+    C    + KE    P FV++   L    G+ V L A   G+    +TW K    
Sbjct: 4836 VGKCG--CMATHLLKEP---PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEV 4890

Query: 531  IIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            I  + ++++    G + L IP  + S    Y C A+N AGS  +   L
Sbjct: 4891 IREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGEL 4938



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 142/668 (21%), Positives = 245/668 (36%), Gaps = 78/668 (11%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F T    L  +   S   +C++       + V W+     L      +T        
Sbjct: 7005 PPYFVTELEPLEAAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTNNVAT 7062

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L    V   D+G YTCKA N  G A+     +++ R       QLP  F      ++ +E
Sbjct: 7063 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER-------QLPPSF---ARQLKDIE 7112

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
            +T+     +T       P +     +D + + +   +             ++ D  H+G+
Sbjct: 7113 QTVGLPVTLTCRLNGSAPIQ-VCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQ 7171

Query: 3737 -------PFATGSRVHTLND--------FGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
                   P  T S    L          F    + ID I A ++ ++ C  T       T
Sbjct: 7172 YSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVI-AGESADFECHVTGAQPMRIT 7230

Query: 3782 TAK------------ITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTP 3829
             +K            ITC      +   ++ +G SG+   +       D    +  V  P
Sbjct: 7231 WSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 7290

Query: 3830 PKFITQIKSHTV-EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PKF+ ++++  V ++ E ++ EC++     P++++ W+RN   L    +Y   +      
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGS--PEIKVSWFRNDSELHESWKYNMSFINSVAL 7348

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRG-MKRSEALTQME 3947
            L I    AEDSG+YIC A N  G D + +T    K P +  Q   P G +K S+ + Q E
Sbjct: 7349 LTINEASAEDSGDYICEAHNGVG-DASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCE 7407

Query: 3948 ATIKKYTSEVYLTEDDLYDVDKK---QPPRFVTQIQSQTSLVEMETTKFECQLA-PVGDP 4003
             +       V++ +       KK       F T +    +L   +  ++ C+    VG  
Sbjct: 7408 ISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHI-LNLEASDVGEYHCKATNEVGSD 7466

Query: 4004 NMKVEWFFNGKPLLHK---NRFTPIYDF--------GYVAMNFGWVYPEDSGEYLCRATN 4052
                   F   P   K   +  T I D         G+  ++  W+  +D GE +  + N
Sbjct: 7467 TCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWL--KDRGEVIRESEN 7524

Query: 4053 LYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQV-TPEQVVEESKARCPP 4111
                          G P      +    +K+   +RE  A   V  P +++E+       
Sbjct: 7525 TRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEK------- 7577

Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIP 4170
                 P+ +TV  G      C VTG P+    W  +G  +   S++ +T+ + +    IP
Sbjct: 7578 -----PEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIP 7632

Query: 4171 KTRQYDTG 4178
                 D G
Sbjct: 7633 CAEMSDKG 7640



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 97/373 (26%), Positives = 160/373 (42%), Gaps = 46/373 (12%)

Query: 4444  WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
             W ++   I+ SP  +         L I  V + D+  +  V          +A LVVEE 
Sbjct: 12078 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE- 12136

Query: 4504  RRQGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                     +P  F  T  + V V  GQ + L  ++   K  DV W K+GK V       +
Sbjct: 12137 --------LPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIV 12186

Query: 4563  LEEDGTY-TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
                 G    L I +A   D+G Y  V + +A    C + CV  +   +D           
Sbjct: 12187 PGVIGLMRALTINDADDTDAGTY-TVTVENANNLEC-SSCVKVVEVIRD----------- 12233

Query: 4622  PPEIIEPLKDK-IVAEGQAIEFSCKIVGKPLPTVQWYKG-DKL-IKPSKYFQMSRTADEY 4678
                +++P++D+ +  +G AI F+C I  K  P ++W+KG D++  +P+   ++ R  +  
Sbjct: 12234 --WLVKPIRDQHVKPKGTAI-FACDI-AKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHL 12289

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
              L+I  A PED  +Y   A    G+    AKL + + +    +  L P+ D+ +YE + A
Sbjct: 12290 YLKIKNAMPEDIAEY---AVEIEGK-RYPAKLTLGERE----VELLKPIEDVTIYEKESA 12341

Query: 4739  QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              F  +I+    P  QW  +G L+  +P  ++  EG    L +     +  G    +A  A
Sbjct: 12342 SFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLRKVKLDQAGEVLYQALNA 12400

Query: 4799  AGQVETSAKLVVK 4811
                  T+A L VK
Sbjct: 12401 I----TTAILTVK 12409



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 54/220 (24%), Positives = 90/220 (40%), Gaps = 5/220 (2%)

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
            TE +  +   + + D+ +  T  ++ + ++A AP   +  +  +V  G + +F C +   
Sbjct: 4351 TEDHQGEYVCEALNDSGKTATSAKLTVVKRA-APVIKRKIEPLEVALGHLAKFTCEIQSA 4409

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
            P     WF   R+I +     I  ++  + +L I    + D G  TC A N+ G  +   
Sbjct: 4410 PNVRFQWFKAGREIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTA 4468

Query: 479  RLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
             L V E      P F+ R  +L    G+         GTP     WQKDG  + P+P  +
Sbjct: 4469 TLTVTE---AYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWK 4525

Query: 539  IHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            I        L++      D   Y C A N  G+   +A L
Sbjct: 4526 ISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAEL 4565



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 63/249 (25%), Positives = 104/249 (41%), Gaps = 19/249 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    +    + + +   YE  +   G   + + W+ +   I+ S + R  +   + 
Sbjct: 8231 PPRFIKKLEPSRIVKQDEFTRYECKI--GGSPEIKVLWYKDETEIQESSKFRMSFVDSVA 8288

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            VLE+      DSG Y+C A N  G A  S  L    K K + P F      IE LK G  
Sbjct: 8289 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL----KVK-EPPIFRKKPHPIETLK-GAD 8342

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             H EC +     P   + WY + + +R   + K +S+     + I      D GEY C+A
Sbjct: 8343 VHLECEL--QGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKA 8400

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
             N  G D       C   G + L++  P  + K+ ++ ++ G + Q  +T     P  + 
Sbjct: 8401 TNDVGSD------TCV--GSIALKA-PPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVV 8451

Query: 3287 QIQDVTKLV 3295
              +D  ++V
Sbjct: 8452 WFKDKGEIV 8460



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 52/188 (27%), Positives = 79/188 (42%), Gaps = 7/188 (3%)

Query: 392  PQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            PQF+K      V   G+ T F+C++TG P   V+W+++  +I     H I   + G    
Sbjct: 5788 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFID-GLATF 5846

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             I+   + +SG   C ARN +G  +    L V E      P F+     + V +   V L
Sbjct: 5847 QISGARVENSGTYVCEARNDAGTASCSIELKVKEP-----PTFIRELKPVEVVKYSDVEL 5901

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 GTP   +TW K+   I  + +  +        L I +   SD   YQC   N  G
Sbjct: 5902 ECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGG 5961

Query: 571  STATRARL 578
            S +   R+
Sbjct: 5962 SCSCSTRV 5969



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 66/274 (24%), Positives = 113/274 (41%), Gaps = 9/274 (3%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G +A FE  + G     ++W++    +     Y++     T  + +L  ++G GD G+YT
Sbjct: 7212 GESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRIL--KVGKGDSGQYT 7269

Query: 146  CTARNQYGEAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204
            C A N  G+ +CS  +   E               +  S  +E K  G+        R  
Sbjct: 7270 CQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRND 7329

Query: 205  QKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVS 264
             ++  +   + S  +   + T       +    + I + + G  D   ST    +L   +
Sbjct: 7330 SELHESWKYNMSFINSVALLTINEASAEDSG--DYICEAHNGVGDASCST----ALTVKA 7383

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   QKP      +G+D   Q ++SG P   V W K+ +++ NS K +I + H  T+L 
Sbjct: 7384 PPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLH 7443

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            + N + SD G Y   A N  G    S  +  + P
Sbjct: 7444 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEP 7477



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 52/198 (26%), Positives = 91/198 (45%), Gaps = 7/198 (3%)

Query: 382  RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            ++ +SE  + P F       D+  G+   F C VTG    ++TW  ++R+IR   N+K+ 
Sbjct: 8129 KLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMT 8188

Query: 442  VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
            + E+    L +  V   D+G  TC A N +G+ +    L V E      P+F+++     
Sbjct: 8189 LVEN-TATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEP-----PRFIKKLEPSR 8242

Query: 502  -VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             V++ E      +  G+P  ++ W KD   I  + + R+      + L++      D+  
Sbjct: 8243 IVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGD 8302

Query: 561  YQCTAQNVAGSTATRARL 578
            Y C A N AGS ++   L
Sbjct: 8303 YTCEAHNAAGSASSSTSL 8320



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 95/397 (23%), Positives = 159/397 (40%), Gaps = 50/397 (12%)

Query: 4413  FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
             F   ++   V E  QARFE     E   +  W +    IK+S  F I     K IL+I  
Sbjct: 12415 FAVPLKDVTVPERRQARFECVLTREANVI--WSKGPDIIKSSDKFDIIADGKKHILVIND 12472

Query: 4473  VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
                +D  V+ A  E +    K SA L V   R +         F    ++  V  G+   
Sbjct: 12473 SQFDDEGVYTAEVEGK----KTSARLFVTGIRLK---------FMSPLEDQTVKEGETAT 12519

Query: 4533  LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
                +++  K + V W KN  K+       I  E  T+ L + E           V ++  
Sbjct: 12520 FVCELSHEK-MHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKE-----------VTLDDI 12567

Query: 4593  GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
              + +     V  L +T      Q K   A P     L DK   E   I   C+ V K +P
Sbjct: 12568 SQIKAQ---VKELSSTA-----QLKVLEADPYFTVKLHDKTAVEKDEITLKCE-VSKDVP 12618

Query: 4653  TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
              V+W+K  + I PS  + +        L+I +A  +D+G+Y C       +  V  + ++
Sbjct: 12619 -VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARL 12677

Query: 4713  TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI--QWLREGALIPETPDFQMI 4770
              + ++        PL  + V+ G+ A F+ +++   +P +  QW  +G  +  +PD ++I
Sbjct: 12678 IKVEK--------PLYGVEVFVGETAHFEIELS---EPDVHGQWKLKGQPLTASPDCEII 12726

Query: 4771  HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
              +G   +L++ N     TG  + +A  A        K
Sbjct: 12727 EDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVK 12763



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 78/308 (25%), Positives = 130/308 (42%), Gaps = 41/308 (13%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
            GR  +         ++VNV  G    L+ KV+      V W  N ++++PD R + + + 
Sbjct: 2438 GRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2497

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
                L+I   +  D G Y+ +        R +  C +S+   K               II
Sbjct: 2498 TKQRLVINRTHASDEGPYKLIV------GRVETNCNLSVEKIK---------------II 2536

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              L+D    E Q + F  ++    +  V W   DK IKPS  +++      Y L +    
Sbjct: 2537 RGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMM 2595

Query: 4687 PEDEGDYKCVAYNS--AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
             +DEG Y   A  +  +G++TVA                  PL D  V E Q A F+ ++
Sbjct: 2596 KDDEGKYTFYAGENITSGKLTVAGGA------------ISKPLTDQTVAESQEAVFECEV 2643

Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
             +      +WLR+G  +P T + +   +G+   L+I  T  +D G +T +  T+    +T
Sbjct: 2644 ANPDSKG-EWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KT 2698

Query: 4805 SAKLVVKS 4812
            SAKL V++
Sbjct: 2699 SAKLKVEA 2706



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 66/306 (21%), Positives = 123/306 (40%), Gaps = 9/306 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  +N       +A F+  + G+P   ++W +    L E +   + + +     +
Sbjct: 5974 PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVA--T 6031

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I+ +  G  G YTC A+N+ G   C  ++  +                    T+E   
Sbjct: 6032 LQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVV 6091

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             GT     +  +  +++  +     S    F+ +   +R+ + V  ++S    +  E+D 
Sbjct: 6092 AGTPELKVKWLKDGKQIVPSRYFSMS----FENNVASFRI-QSVMKQDSGQYTFKVENDF 6146

Query: 251  QIST--EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
              S+     R L    PP   +K        G+    + ++SG+      WFK+G+ +  
Sbjct: 6147 GSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 6206

Query: 309  SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
            S K+ ++      +L V N +  D+ +YT    N  G    SG L V+ P    V+  R 
Sbjct: 6207 SAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQ 6266

Query: 369  QYITDT 374
            Q I D+
Sbjct: 6267 QAIPDS 6272



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 54/192 (28%), Positives = 85/192 (44%), Gaps = 12/192 (6%)

Query: 3044 TGRPPEFTTVF--KDI-VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
            T R P+ +  F  K + +D+  G+ A +E  +  TG Q M I W  + K I         
Sbjct: 7190 TAREPKKSPFFDIKPVSIDVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTIT 7247

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL     DSG Y+C+ATN  G+   S +L     S  + P+F   ++  + 
Sbjct: 7248 CVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL-----SVKEPPKFVKKLEASKV 7302

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
             K G+S   EC +     P++K+ W+ N   +  S +          +L I      DSG
Sbjct: 7303 AKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSG 7360

Query: 3221 EYVCRAYNKYGE 3232
            +Y+C A+N  G+
Sbjct: 7361 DYICEAHNGVGD 7372



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 98/399 (24%), Positives = 165/399 (41%), Gaps = 52/399 (13%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            KK +     E+    FEV    + +P +KW+ +N  IK S   ++ +      L+++ + 
Sbjct: 2799 KKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 2857

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
              D+  + AV     G  +C A L VE               T T +N+ V   +    +
Sbjct: 2858 PSDAGEYTAVV----GQLECKAKLFVETLH-----------ITKTMKNIEVPETKTASFE 2902

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +V+    +   WLKNG +++   + KI+ +   + L+I+    +DS +Y  V     G 
Sbjct: 2903 CEVSHFN-VPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGN 2957

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V+                 P  I   LKD    E   I F   +  + + + 
Sbjct: 2958 DQVSATLTVT-----------------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SY 2999

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W K    IK +   QM      ++L I      D  DY  V    AG+ T  A L V  
Sbjct: 3000 KWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFV----AGKATSTATLYV-- 3053

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
              +A ++     ++DI V E + A F+ ++ S+   T+QW+++   +  T   ++  E  
Sbjct: 3054 --EARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               LLI +T   D G +T     A G V T AKL V+ +
Sbjct: 3111 VHRLLIPSTRMSDAGKYT---VVAGGNVST-AKLFVEGR 3145



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 120/546 (21%), Positives = 212/546 (38%), Gaps = 85/546 (15%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            +Y   A R        V   + P+ L  L+    +  G+ A F A +  +      + WY
Sbjct: 3217 EYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVT-VQSGKPARFCAVISGRPQ--PKISWY 3273

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
               + +++  + +  HD     L +     ED+ VYT  A+N  G A  SAS++VE    
Sbjct: 3274 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV--- 3330

Query: 1141 IDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECR 1200
                                + V P    +E+    P  + PL +    SEG+    +CR
Sbjct: 3331 -------------------PEVVSP---DQEMPVYPPAIITPLQD-TVTSEGQPARFQCR 3367

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
               +    ++V W+   + +     F+         L+I  A   D G YT  A N +G 
Sbjct: 3368 ---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ 3424

Query: 1261 AHTSAIVRVIERSDIVTDTQNEQAIE-------------QIQLLEDAARRTKQVREDITV 1307
              ++A +  +E  + +   + EQ IE             + + L  A  +  ++ E + +
Sbjct: 3425 VSSTANLS-LEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLEL 3483

Query: 1308 M-QAPQFSRALHN---------IETVEGTNVHL----ECRLQPVGDQTMRVEWFCNGKPI 1353
            + ++P +S    +         I+ V   ++ +       +  +G    +++WF NG  +
Sbjct: 3484 LSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLL 3543

Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK----KDLI 1409
                 ++  ++ D  +L +L    ED G YTC A+N  G+ + S  L++ +K    KD  
Sbjct: 3544 TPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTE 3603

Query: 1410 LESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLE 1469
             ES     LEK+                      P F+   K I    +G    FE  + 
Sbjct: 3604 TESAVAKSLEKL-----------------GGPCPPHFLKELKPI-RCAQGLPAIFEYTV- 3644

Query: 1470 PVTDSNLKVEWFKNGQPVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             V +    V WFK  + +     +  IH+  G     + D   EDSG+Y C+A N++G  
Sbjct: 3645 -VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGES 3703

Query: 1529 EVSCRL 1534
              +  L
Sbjct: 3704 TCAAEL 3709



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 6/182 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P FVK   D     G+       V G     VTW      IR+D   K+  + +G   L+
Sbjct: 4851 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGVAVLI 4909

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            I +V +S  G  TC+A N++G       L  I KE     K +ER   + V  G+P  L 
Sbjct: 4910 IPDVQISFGGKYTCLAENEAGSQTSVGEL--IVKEPA---KIIERAELIQVTAGDPATLE 4964

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
                GTP  +  W KDG P++ + + RI      + L    A+  D+  Y     N  GS
Sbjct: 4965 YTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGS 5024

Query: 572  TA 573
            ++
Sbjct: 5025 SS 5026



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 6/200 (3%)

Query: 380  EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
            E    + ++ +AP F K  ++ D       R DC++ G     V+WF + ++I     ++
Sbjct: 5028 ETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYR 5087

Query: 440  ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
            I   E G  +L I  V ++D+G  TC A N  G       L V E      P FV +  +
Sbjct: 5088 IAFVE-GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEP-----PSFVTKPGS 5141

Query: 500  LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             +V  G  V L +   G+    I W K    ++      I  +   S+L++   K SD+ 
Sbjct: 5142 KDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSG 5201

Query: 560  WYQCTAQNVAGSTATRARLY 579
             Y C   NVAG     A L+
Sbjct: 5202 TYTCKVSNVAGGVECSANLF 5221



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 64/255 (25%), Positives = 105/255 (41%), Gaps = 19/255 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP+F      ++ +  GQ   +E  +  TG   + + W+ +G  I A  +    +  G+ 
Sbjct: 5787 PPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFIDGLA 5844

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
              +I G +  +SGTY C A N  G A  S++L    K K + P F   ++ +E +K    
Sbjct: 5845 TFQISGARVENSGTYVCEARNDAGTASCSIEL----KVK-EPPTFIRELKPVEVVK-YSD 5898

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               EC V     P  ++ W  N + +R S +           L I      D+GEY C  
Sbjct: 5899 VELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIV 5956

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
             N+ G        +C     V L+   P  + KI    ++  +     ST +  PP  IT
Sbjct: 5957 SNEGG--------SCSCSTRVALKE-PPSFIKKIENTTTVLKSSATFQSTVAGSPPISIT 6007

Query: 3287 QIQDVTKLVEGQSAH 3301
             ++D   L E  + +
Sbjct: 6008 WLKDDQILDEDDNVY 6022



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 72/298 (24%), Positives = 117/298 (39%), Gaps = 16/298 (5%)

Query: 3513 QGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI---- 3568
            + +  + ++ ++   + GT  +    E   G    +T  A    P E   TP  L+    
Sbjct: 891  KSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLK 950

Query: 3569 ---LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
               + E  S   EC +      S  V W+     + +    +     G   L I   +  
Sbjct: 951  NVTVIEGESVTLECHISGY--PSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 1008

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ-LPSHFKSGTESIQKLEETLHKREE 3684
            D+G +TC A N  G  + SC L V+  +    E   +   F +  +   +  + +     
Sbjct: 1009 DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTS 1068

Query: 3685 ITIEDEKPNPPRFTVEIKDNI--DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742
            +T E   P  P     I   +   + EGG V F C+V   G+P   + W  +G P  TG 
Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1126

Query: 3743 R--VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
            R  V      G   L I   +A DAGEYT    NK G  + +A +   A  +++++SQ
Sbjct: 1127 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 56/195 (28%), Positives = 85/195 (43%), Gaps = 5/195 (2%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            I E+ L P F +  +D   T G    F+CR+ G    +V+W+ +   ++DD N  +  + 
Sbjct: 8036 IKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDAN--LQTSF 8093

Query: 445  SGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
              N A L I     S  G   C A N  G  +   +L + E E  V P F  +  ++++ 
Sbjct: 8094 VHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE--VPPFFDLKPVSVDLA 8151

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             GE         GT   +ITW KD   I P    ++      +TL + +    DA  Y C
Sbjct: 8152 LGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTC 8211

Query: 564  TAQNVAGSTATRARL 578
             A N+AG  +  A L
Sbjct: 8212 YASNIAGKDSCSAHL 8226



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/282 (24%), Positives = 121/282 (42%), Gaps = 20/282 (7%)

Query: 3667 SGTESIQKLEETLHKREEITIED-------EKPNPPRFTVEIKDNIDVPEGGPVHFDCRV 3719
            +GT   ++  E LH RE    E        E P  P   V    N+ V EG  V  +C +
Sbjct: 907  TGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHI 966

Query: 3720 EPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779
               G P+  + W+       +          G   L I   +A D+G +TC A N+ G+ 
Sbjct: 967  S--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 1024

Query: 3780 TTTAKITCSAKRDIVLESQ-LPQGMSGEKIKELERGRI--SDAPKEE----PIVSTPPKF 3832
            +T+  +      +   E+  + +  + E+ + +E   +  +D    E    P     P F
Sbjct: 1025 STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1084

Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM--GFVSLD 3890
            IT+     + E   V F C+V    +PK  + W ++G  L +G+RY+  Y+   G   L 
Sbjct: 1085 ITKPVVQKLVEGGSVVFGCQVGG--NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLV 1142

Query: 3891 ILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            I   +A+D+GEY     N  GE    A++  +   ++++++Q
Sbjct: 1143 ISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/271 (25%), Positives = 121/271 (44%), Gaps = 16/271 (5%)

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320
            RE +  + A+   P      PP  ++ +++VT ++EG+S   E  +     P   V W+ 
Sbjct: 922  REAKVTETARVPAPVEIPVTPPTLVSGLKNVT-VIEGESVTLECHISGYPSPT--VTWYR 978

Query: 3321 NGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
               ++     ++     GI  L I   + E+SG + C A N+ G  ST   L     E  
Sbjct: 979  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 1038

Query: 3381 ILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKG-----KAPVF-TVPLSNIENLRE 3434
              ++      +   E+ + +E   V   DTS+ EE+       AP F T P+  ++ L E
Sbjct: 1039 EKETTAVT-EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVE 1095

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSGE 3492
            G +  F  ++     P+  V W  +G  L  G R++   +   G   L IS T+ +D+GE
Sbjct: 1096 GGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1153

Query: 3493 YLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            Y     N +GE   +AS+  +    ++++SQ
Sbjct: 1154 YTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 8/194 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F+   +D+ + + G    ++ ++  +G + + + W+ +GK ++ S  ++T +     
Sbjct: 8983 PPSFSRQLRDVQE-TVGLPVVFDCAI--SGSEPISVSWYKDGKPLKDSPNVQTSFLDNTA 9039

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L I  T  + +G YSC ATN  G A  S +L   +      P F   +  ++ +  G+S
Sbjct: 9040 TLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGK--NPPFFDIRLAPVDAVV-GES 9096

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A FEC V       +K+ W  + + +R   + +         L +      DSG+Y C A
Sbjct: 9097 ADFECHVTGTQ--PIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYA 9154

Query: 3227 YNKYGEDFTRATIN 3240
             N+ G+D   A +N
Sbjct: 9155 VNEVGKDSCTAQLN 9168



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 89/373 (23%), Positives = 153/373 (41%), Gaps = 52/373 (13%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E A F+ E   E +P ++WY +   ++ S      +      L +R V +ED+      A
Sbjct: 13138 ETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTA 13196

Query: 4486  ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
             ++     K  ANL V+E          P  FT   ++  V  G    L+ +V+  +   V
Sbjct: 13197 KD----FKTHANLFVKEP---------PVEFTKPLEDQTVEEGATAVLECEVS-RENAKV 13242

Query: 4546  YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
              W KNG ++    + +I+ +     L+I +  P+D   Y C A +   +  C+   V   
Sbjct: 13243 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSCNLNVV--- 13297

Query: 4606  PATKDKPKPQTKAANAPP--EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
                             PP  E + PL D  V E +   F C++  +    V+W+K    I
Sbjct: 13298 ----------------PPHVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEI 13340

Query: 4664  KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS--AGRVTVAAKLKVTQPDQADNL 4721
             K  K + +        L I++   +DE +Y C    +  +G +TV  +  V   +     
Sbjct: 13341 KKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKN----- 13395

Query: 4722  PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
                  L +I V E    +   ++ SK    + W +    I ET  ++++ EG   +L+I 
Sbjct: 13396 -----LANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 13449

Query: 4782  NTYEEDTGTFTCR 4794
             N + ED G + CR
Sbjct: 13450 NAHLEDAGNYNCR 13462



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 16/234 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLS--GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            P   +K  + +L+    A F+ +L+  G+P   V W  +G+ L  +N+  +I    + +L
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1762

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG  T  A N  G   TS  L V+       + Q  +     Q+ E  ER+
Sbjct: 1763 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1822

Query: 384  EISEKALA-----------PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
               E AL            P  V   +   V EG+  RF CRVTG P P+V W++N + I
Sbjct: 1823 -AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLI 1881

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
            R   + +  V   G H L I +    D+G V   A N  G    + +L + ++E
Sbjct: 1882 RK--SKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1933



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 111/504 (22%), Positives = 202/504 (40%), Gaps = 49/504 (9%)

Query: 71   PPIF-EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP F +++  +     G +A+   KL+G+P   V+W +    L E N   M +     + 
Sbjct: 4663 PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYF--VNSEA 4720

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
             L I  +   D G Y+C A N  G   CS  I  +               R  +  ++ +
Sbjct: 4721 ILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCE 4780

Query: 190  AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFK-VDTFEYRLLREVSFRESITKRYVGES 248
              GT  +     +  +++  +      S      ++ F +    +V   E +    VG+ 
Sbjct: 4781 VSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSA-DVGEYECVVANEVGKC 4839

Query: 249  DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
               ++T + +      PP   +K  +     G     Q  + G+    VTW K  + +  
Sbjct: 4840 GC-MATHLLKE-----PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIRE 4893

Query: 309  SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
              K ++  ++    L + + Q S  G YT LAEN  G   + G L V+ P +     +R+
Sbjct: 4894 DGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKII---ERA 4950

Query: 369  QYITDTQ-QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            + I  T     T E        L P++ K        +G+       V  + Y  +++  
Sbjct: 4951 ELIQVTAGDPATLEYTVAGTPELKPKWYK--------DGRPL-----VASKKY-RISFKN 4996

Query: 428  NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
            N  Q++  Y+ ++  ++SG +   I+N    + G  +C       ET F     V++++ 
Sbjct: 4997 NVAQLK-FYSAEL--HDSGQYTFEISN----EVGSSSC-------ETTF----TVLDRD- 5037

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
             +AP F +    ++        L+ +  G+   R++W KDG  I  +   RI    G ++
Sbjct: 5038 -IAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 548  LDIPRAKASDAAWYQCTAQNVAGS 571
            L+I R   +DA  + C A N  GS
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGS 5120



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 51/178 (28%), Positives = 82/178 (46%), Gaps = 7/178 (3%)

Query: 402  DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
            DV  G+   F+C VTG     +TW  ++++IR   N+ I    +  H L I  V   DSG
Sbjct: 7208 DVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPH-LRILKVGKGDSG 7266

Query: 462  VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV-REGEPVVLNARAVGTPTP 520
              TC A N  G+     +L+V E      PKFV++     V ++GE + L  +  G+P  
Sbjct: 7267 QYTCQATNDVGKDMCSAQLSVKEP-----PKFVKKLEASKVAKQGESIQLECKISGSPEI 7321

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +++W ++   +  + +  +      + L I  A A D+  Y C A N  G  +    L
Sbjct: 7322 KVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTAL 7379



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 52/187 (27%), Positives = 83/187 (44%), Gaps = 6/187 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F+K  ++          F   V G P   +TW  +D+ + +D N  I   +S    L 
Sbjct: 5975 PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVA-TLQ 6033

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            I +V    SG  TC A+N+SG       L V E  Q+V     E+  +++V E +P+ L 
Sbjct: 6034 IRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIV-----EKAKSVDVTEKDPMTLE 6088

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
                GTP  ++ W KDG  I+P+    +  +   ++  I      D+  Y    +N  GS
Sbjct: 6089 CVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGS 6148

Query: 572  TATRARL 578
            ++  A L
Sbjct: 6149 SSCDAYL 6155



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 76/284 (26%), Positives = 117/284 (41%), Gaps = 24/284 (8%)

Query: 1553 EQIQVLEDR-SKYHRTDMVD---EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDAT 1608
            E+ +VL  R +K   T  V    E+    P   + LKNV + EG+    E  +      T
Sbjct: 914  ERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT 973

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
              V WY  +  ++S   F  T   G   L I     EDSG +TC A+N  G   TS    
Sbjct: 974  --VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLA 1031

Query: 1669 VHSKKSIYLES----------QHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVF-TMPM 1717
            V   +    E+          +      R   + DTS  +  +   E    AP F T P+
Sbjct: 1032 VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGE--PAAPYFITKPV 1089

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYVALNMKYV 1775
               ++ E  +  F  ++   G+PK  V W ++GVP+    R    ++   G   L +   
Sbjct: 1090 VQ-KLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMT 1146

Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
              +D+G YT    N+ GE   S++L  ++   L ++SQ E   Q
Sbjct: 1147 FADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQ 1190



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 62/286 (21%), Positives = 112/286 (39%), Gaps = 10/286 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  K     +  + + E ++ G P   V+W +    +    KY++   ++    +
Sbjct: 5881 PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL--TDRVSVFN 5938

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I +  P D GEY C   N+ G   CS  +  +                  S T +   
Sbjct: 5939 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTV 5998

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G+   +    +  Q +   +    S  D   V T + R     S     + RY  ++  
Sbjct: 5999 AGSPPISITWLKDDQILDEDDNVYISFVD--SVATLQIR-----SVDNGHSGRYTCQAKN 6051

Query: 251  QISTEIDRSLGPV-SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
            +   E   +   V  P +I +K ++  + E      +  ++G P  +V W K+G++++ S
Sbjct: 6052 ESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPS 6111

Query: 310  NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
                +   +N  + R+++  K DSG YT   EN  G      YL V
Sbjct: 6112 RYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV 6157



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 3/183 (1%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            ++IE+S    AP+  +  Q + V +G    F  RV G+P PE  W+ N  +I        
Sbjct: 2067 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2126

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
               E     L+I +VT  DS  +   A N +GET+    L +++ +Q++   F +    +
Sbjct: 2127 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLIT--FTQELQDV 2183

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +E + +         P  ++ W KDG+ +    + R+H+D     L I     SDA  
Sbjct: 2184 VAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAED 2243

Query: 561  YQC 563
            Y C
Sbjct: 2244 YSC 2246



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 82/337 (24%), Positives = 143/337 (42%), Gaps = 46/337 (13%)

Query: 242  KRYVGESDVQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF 300
            K  VG+S+  +S  + DR    + PP   +K ++     GA    + ++SG+    V WF
Sbjct: 7647 KNSVGKSNCTVSVHVSDR----IVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWF 7702

Query: 301  KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
            ++G  +++  K +   + N  TL +   + SD+G YT +A N  G    S  L V+ P  
Sbjct: 7703 QDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEP-P 7761

Query: 361  SYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ-DRDVTEGKMTRFDCRVTGRP 419
            S+ Q   S  +           I    +   P  VK  +  R++  G+     C ++   
Sbjct: 7762 SFEQTPDSVEVLPGMSLTFTSVI----RGTPPFKVKWFKGSRELVPGE----SCNIS--- 7810

Query: 420  YPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCR 479
               +  F+ + ++      ++   ESG+++ ++TN    D+G  +C              
Sbjct: 7811 ---LEDFVTELEL-----FEVQPLESGDYSCLVTN----DAGSASCTT------------ 7846

Query: 480  LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539
             ++  KE      FV+R +  +V  G P+VL A   GTP   ++W KD   I  +    I
Sbjct: 7847 -HLFVKEPAT---FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSI 7902

Query: 540  HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
                 ++ L+I  +   D A Y C  +N AG     A
Sbjct: 7903 TMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEA 7939



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 69/247 (27%), Positives = 97/247 (39%), Gaps = 11/247 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P     L N+  + EGE+   E  ++    P   V WY     +++   F+     G   
Sbjct: 943  PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIAR 999

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDK-IAAL 3538
            L I   + EDSG + C A N  G   T+  + VQ       E+        T +K     
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059

Query: 3539 EGYSGTVDTLTPE-AESGNP--PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
                 T  +LT E A  G P  P F T P    L E  S  F C++    +    V W  
Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKK 1117

Query: 3596 NGKPLLTGSRVKTI--NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G PL TG R K       G   L I   +  DAG YT    N+HGE + S  L  +   
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1177

Query: 3654 GIILEPQ 3660
             ++++ Q
Sbjct: 1178 ELLMKSQ 1184



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 90/395 (22%), Positives = 159/395 (40%), Gaps = 30/395 (7%)

Query: 1170 EEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            E + K  P F++ L  P  +  G N  L+C  E  G     + WF + + +    +++ +
Sbjct: 4751 EIVIKEPPSFIKTLE-PADIVRGTNALLQC--EVSGTGPFEISWFKDKKQIRSSKKYRLF 4807

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE-QI 1288
                 V L+I    SAD GEY     N +G     A   + E    V    +  A+  Q 
Sbjct: 4808 SQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQT 4867

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHL----ECRLQPVGDQTMRV 1344
              L+ A R ++ +   +T M+  +  R    I+      V +    + ++   G  T   
Sbjct: 4868 VTLQAAVRGSEPI--SVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLA 4925

Query: 1345 EWFCNGKPIKTGHRF--RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEA-------- 1394
            E    G     G      PA   +   L  ++     +  YT   T +L           
Sbjct: 4926 ENEA-GSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPL 4984

Query: 1395 VTSCALRVIAKKDLILESQHPSGL-EKIQYLEDTSRYKKTDIIDESVTIKPR----FVTR 1449
            V S   R+  K ++     + + L +  QY  + S    +   + + T+  R    F T+
Sbjct: 4985 VASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTK 5044

Query: 1450 P-KSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            P +++++V+ G     +CK+       ++V WFK+G+ +    R+R     G  +L+II 
Sbjct: 5045 PLRNVDSVVNGT-CRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIR 5101

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            +   D+G +TCRA N VG+ + S  L  +     V
Sbjct: 5102 VDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFV 5136



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 37/91 (40%), Positives = 51/91 (56%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP ++  LK+  V EG+++   C I G P PTV WY+ D  I+ S  FQ++  +    L 
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            I EAF ED G + C A N AG V+ +  L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 65/233 (27%), Positives = 94/233 (40%), Gaps = 15/233 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
            EG+    E  +   G PS    WY    +++    F+ T   G   L I    A D+G +
Sbjct: 956  EGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013

Query: 2582 MCKAINRAGXXXXX------XXXXXXXXXXIIDQAMRPESWEQIQLKEAAM--NKVPEMF 2633
             C A+N AG                      + +    E    ++ ++  M    + E  
Sbjct: 1014 TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1073

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
               G   AP F T      KLVEG  V    QV     P+  + W K+GV LTTG R K 
Sbjct: 1074 AGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKV 1130

Query: 2694 TFD--FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
            +++   G   L I+    DD+G YT    N  GE  ++AS+  E  + LL +S
Sbjct: 1131 SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1183



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 75/321 (23%), Positives = 126/321 (39%), Gaps = 27/321 (8%)

Query: 240  ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
            + +   G S + +   ++     V P    +K +N  ++EG+  + +V+ +GNP P + W
Sbjct: 1531 VAQNRAGRSSISVILTVEAVEHQVKP-MFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVW 1589

Query: 300  FKNGQRLINSN--KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE- 356
             KN   ++     K  I  T     L++ +T   DS  YT  A N  G   T   + VE 
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649

Query: 357  ------------SPTESY------VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
                         P  +Y        +    ++   Q++  E  +   EK   P F K  
Sbjct: 1650 EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKL 1709

Query: 399  QDRDVTEGKMTRFDCRVT--GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
                +       F+CR+T  G P   V W ++D +  +  N   ++NE G  +L      
Sbjct: 1710 TSLRLKRFGPAHFECRLTPIGDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLDYGVAY 1768

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE--RFSTLNVREGEPVVLNARA 514
              DSG++TC A NK G       L V +++ +V    +   R     + E E +      
Sbjct: 1769 SRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGAL 1828

Query: 515  VGTPTPRITWQKDGVPIIPNP 535
             G  T +   QK  + + P P
Sbjct: 1829 TGVTTDQKEKQKPDIVLYPEP 1849



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 65/248 (26%), Positives = 96/248 (38%), Gaps = 19/248 (7%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K    PIF K++    +   + A   V   G P P I+W+     +  S D++       
Sbjct: 3498 KEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDD 3557

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR---------------GG 4510
              LII    +ED   +  +A N  G   CSA L +  K    +               GG
Sbjct: 3558 HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 3617

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTY 4569
              PP F    + +    G     +  V G     V W K  K++   +   I+   +G+ 
Sbjct: 3618 PCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 3677

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT--KDKPKPQTKAANAPPEIIE 4627
            T ++ +   +DSG Y C A N  GE+ C AE +V L  T   D P        AP +  +
Sbjct: 3678 TFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQ 3737

Query: 4628 -PLKDKIV 4634
             PLK   V
Sbjct: 3738 TPLKGPAV 3745



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 96/405 (23%), Positives = 167/405 (41%), Gaps = 51/405 (12%)

Query: 4409  KPPI-FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
             +PP+ FTK ++   V E   A  E E   E    +KW++    I  S  ++I        
Sbjct: 13209 EPPVEFTKPLEDQTVEEGATAVLECEVSRENAK-VKWFKNGTEILKSKKYEIVADGRVRK 13267

Query: 4468  LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP--SFTLTAQNVNV 4525
             L+I     ED   +   A++     K S NL            +VPP   F     ++ V
Sbjct: 13268 LVIHDCTPEDIKTYTCDAKD----FKTSCNL-----------NVVPPHVEFLRPLTDLQV 13312

Query: 4526  TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
                ++ R + +++  +   V W K+G +++   +  I+ +     L+I +    D  +Y 
Sbjct: 13313 REKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYS 13371

Query: 4586  CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
             C       E R  A     L   +++       AN     IE      V+E   I+  C+
Sbjct: 13372 C-------EVR-TARTSGMLTVLEEEAVFTKNLAN-----IE------VSETDTIKLVCE 13412

Query: 4646  IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              V KP   V WYKGD+ I  +  +++     +  L I  A  ED G+Y C   +S     
Sbjct: 13413 -VSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSS----R 13467

Query: 4706  VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                K+KV +         ++  +++ + EG+ A+F   I+ +  P +QW R+   +    
Sbjct: 13468 TDGKVKVHEL----AAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGD 13522

Query: 4766  DFQMIHEGNNAVLLIGNTYEEDTGTFTCR--ATTAAGQVETSAKL 4808
              + +I +G   VL++ +   +D GT+     A  AA  +    KL
Sbjct: 13523 KYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKL 13567



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 49/196 (25%), Positives = 82/196 (41%), Gaps = 6/196 (3%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + + ++ + P F K     D   G     +C+V+G       WF + ++I     ++++ 
Sbjct: 6155 LRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVC 6214

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +E  + +L + N+ L D+   TC   N +G+ A    L V E      P F+ +      
Sbjct: 6215 HER-SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEP-----PSFLVKPGRQQA 6268

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
                 V   A   GTP  +I W KD V ++  P+  I  +G  S L++    AS    Y 
Sbjct: 6269 IPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYT 6328

Query: 563  CTAQNVAGSTATRARL 578
            C   N  GS +    L
Sbjct: 6329 CHVTNDVGSDSCTTML 6344



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 68/248 (27%), Positives = 105/248 (42%), Gaps = 17/248 (6%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ +T  P  +  LK    ++EG+S   E  +      T+T  WY    QI S+   Q  
Sbjct: 937  EIPVTP-PTLVSGLKNVT-VIEGESVTLECHISGYPSPTVT--WYREDYQIESSIDFQIT 992

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID---TSSIHRGLYE 1152
               G   L I    AEDSG +T  A N AG    S  + V+     +   T+   +   E
Sbjct: 993  FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTE 1052

Query: 1153 KTRHIEESKFV--EPMYQIEEISKSKPVFVQPLSNP--PPVSEGKNIHLECRLEPMGDPT 1208
            + R +E    V  +     E+    +P     ++ P    + EG ++   C++   G+P 
Sbjct: 1053 EKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPK 1110

Query: 1209 MRVEWFHNGRSVTVGSRFKTYYD--FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
              V W  +G  +T G R+K  Y+   G   L I    + D GEYT+   N  G   TSA 
Sbjct: 1111 PHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG--ETSAS 1168

Query: 1267 VRVIERSD 1274
              ++E +D
Sbjct: 1169 ASLLEEAD 1176



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 103/509 (20%), Positives = 189/509 (37%), Gaps = 52/509 (10%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+ ++  +    A G  AKF  +++  P     W +    + E +K S+R ++    + +
Sbjct: 4383 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4442

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            L  Q+   D GEYTC A N+YG   C+  +                    V +  +    
Sbjct: 4443 LRTQVV--DCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFIC- 4499

Query: 192  GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR--YVGESD 249
                 T   +   + +   +G   S + ++K+   E + + E+S   +I  R  Y  ++ 
Sbjct: 4500 -----TVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILELS-NLTIQDRGVYSCKAS 4553

Query: 250  VQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
             +   +I    L  +  P   ++    +         + Q+  + +  VTW K+GQ+L  
Sbjct: 4554 NKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPP 4613

Query: 309  SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
               ++I       TL +   +  DSG Y   A N  G    S  + V  P  S+V+    
Sbjct: 4614 GKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREP-PSFVKKVDP 4672

Query: 369  QYITDTQQRETEERIEISEK-ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
             Y+    +     R+    K +   Q      +++++E    R              +F+
Sbjct: 4673 SYLMLPGE---SARLHCKLKGSPVIQVTWFKNNKELSESNTVRM-------------YFV 4716

Query: 428  NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
            N   I D  + K  V +SG+++    N   SDS                 C   ++ KE 
Sbjct: 4717 NSEAILDITDVK--VEDSGSYSCEAVNDVGSDS-----------------CSTEIVIKE- 4756

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
               P F++     ++  G   +L     GT    I+W KD   I  + + R+ +      
Sbjct: 4757 --PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVC 4814

Query: 548  LDIPRAKASDAAWYQCTAQNVAGSTATRA 576
            L+I    ++D   Y+C   N  G     A
Sbjct: 4815 LEIFSFNSADVGEYECVVANEVGKCGCMA 4843



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 51/188 (27%), Positives = 78/188 (41%), Gaps = 7/188 (3%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            IE+  K   P F++  +  +V +      +C VTG P  EVTW  N+R+IR    +  L 
Sbjct: 5874 IELKVKE-PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYT-LT 5931

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +      L IT    SD+G   C+  N+ G  +  C   V  KE    P F+++      
Sbjct: 5932 DRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCS--CSTRVALKE---PPSFIKKIENTTT 5986

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
                     +   G+P   ITW KD   +  +  + I      +TL I       +  Y 
Sbjct: 5987 VLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYT 6046

Query: 563  CTAQNVAG 570
            C A+N +G
Sbjct: 6047 CQAKNESG 6054



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 49/193 (25%), Positives = 83/193 (43%), Gaps = 10/193 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP+F    +    +  G  +  E  +   G   + + WF N   + AS + R  +   + 
Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 6406

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            V+++    T DSG + C A N  G    S K+  + K   + P F++    +E LK+ + 
Sbjct: 6407 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV--IVK---EPPVFSSFPPIVETLKNAE- 6460

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               EC +     P  ++ WY + + +R S + K  S      + I      D GEY C+A
Sbjct: 6461 VSLECEL--SGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKA 6518

Query: 3227 YNKYGEDFTRATI 3239
             N+ G D    T+
Sbjct: 6519 QNEVGSDTCVCTV 6531



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 75/317 (23%), Positives = 135/317 (42%), Gaps = 23/317 (7%)

Query: 2041 YAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPI 2100
            + +A+   TY  +A   V + V  S      +   + + L   R  K+ E  +   P P+
Sbjct: 881  FPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERF-EVL-HGREAKVTETARV--PAPV 936

Query: 2101 EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT 2160
            E   P   P  ++ L ++  + EG+    EC +     P  T+ W+    +I +   ++ 
Sbjct: 937  EI--PVTPPTLVSGLKNVTVI-EGESVTLECHISGYPSP--TVTWYREDYQIESSIDFQI 991

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT---QHPNGL 2217
            T   G   L I   +AEDSG + C A N+ G    +C L V        +T         
Sbjct: 992  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTT 1051

Query: 2218 EKIRQLEAQG-HSTRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQVEPVHD 2271
            E+ R +E++    T   + E +  P     P F+T+      + EG +  F CQV    +
Sbjct: 1052 EEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GN 1108

Query: 2272 PNLRIEFYHNGKALQSAARFHITFD--FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSA 2329
            P   + +  +G  L +  R+ ++++   G   L I     +DAGEY++   N  G  +++
Sbjct: 1109 PKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1168

Query: 2330 ISMTVTAKGSIISESQR 2346
             S+   A   ++ +SQ+
Sbjct: 1169 ASLLEEADYELLMKSQQ 1185



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 7/195 (3%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  V+ +++ T ++E E+   EC ++  G P+  V W+     +     F   +  G  
Sbjct: 942  PPTLVSGLKNVT-VIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIA 998

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
             +     + EDSG + C A N  G   T   +          ++       + E+ R +E
Sbjct: 999  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1058

Query: 4092 ASWQVTPEQVVEESKAR----CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
            +   V  +  + E +A       P F++ P    + EG    F C+V G+PKP V W  +
Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1118

Query: 4148 GNTIVNGSRYKLTYD 4162
            G  +  G RYK++Y+
Sbjct: 1119 GVPLTTGYRYKVSYN 1133



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 46/197 (23%), Positives = 86/197 (43%), Gaps = 6/197 (3%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            +++S++A+ P F +  ++     G     +C+V G     V WF    +I     ++   
Sbjct: 6718 VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF 6777

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +++    L + ++  SD G  TCVA N +G    +CR  +  +E    P FV+    L V
Sbjct: 6778 SDNVC-TLQLNSLDSSDMGNYTCVAANVAGSD--ECRAVLTVQEP---PSFVKEPEPLEV 6831

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              G+ V   +   GTP  ++ W +    ++      I+ +   + L++     S +  Y 
Sbjct: 6832 LPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 6891

Query: 563  CTAQNVAGSTATRARLY 579
            C   N AG  +   RL+
Sbjct: 6892 CVVSNNAGQASCTTRLF 6908



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 60/221 (27%), Positives = 97/221 (43%), Gaps = 11/221 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    KDI + + G        L   G   + + W+ +G  +     ++T +   + 
Sbjct: 7101 PPSFARQLKDI-EQTVGLPVTLTCRL--NGSAPIQVCWYRDGVLLRDDENLQTSFVDNVA 7157

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L+IL T  + SG YSC A+N  G A  S +L   +  K   P F     +I+ +  G+S
Sbjct: 7158 TLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKK--SPFFDIKPVSIDVIA-GES 7214

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A FEC V       M+I W  + + +R               L I      DSG+Y C+A
Sbjct: 7215 ADFECHVTGAQ--PMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQA 7272

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQ 3267
             N  G+D   A ++   +   +++ L+   +AK  + ES+Q
Sbjct: 7273 TNDVGKDMCSAQLS-VKEPPKFVKKLEASKVAK--QGESIQ 7310



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 77/331 (23%), Positives = 137/331 (41%), Gaps = 23/331 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I   P   ++ EG  A+F+ +++G P+P+V W+ NGQ +  S +  +     H  L +
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHY-LDI 1899

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-----SYVQDQRSQYITDTQ---QR 377
             + +  D+G   + AENP G I     L ++   +         + R ++        Q 
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQF 1959

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKM--------TRFDCRVTGRPYPEVTWFIND 429
            E ++     +     + VK+ +   +T  K+        ++F  R T   Y E    +  
Sbjct: 1960 EVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR-TEEGYYEAITAVEL 2018

Query: 430  RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQV 488
            +  + D +++ L+ ++ +  L  T   L++          K     F  + + IE    +
Sbjct: 2019 KSRKKDESYEELLRKTKDELLHWTK-ELTEEEKKALAEEGKITIPTF--KPDKIELSPSM 2075

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH-TDGGAST 547
             APK  ER  +  V +G       R VG P P   W K+GV I  +  +  +  +     
Sbjct: 2076 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135

Query: 548  LDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            L I    A D+A     A N+AG T++ A L
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFL 2166



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 45/176 (25%), Positives = 72/176 (40%), Gaps = 3/176 (1%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            VT G+    +C+V G P   V W+ + + +     HK       + +L I +V   D+G 
Sbjct: 6642 VTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS-SLRILSVERQDAGT 6700

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             T   +N  G+++  C   V   ++ V P F  R        G   +L  +  G+    +
Sbjct: 6701 YTFQVQNNVGKSS--CTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISV 6758

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             W  +   I+   + +        TL +    +SD   Y C A NVAGS   RA L
Sbjct: 6759 AWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVL 6814



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 63/232 (27%), Positives = 94/232 (40%), Gaps = 24/232 (10%)

Query: 3011 ERTQHPKGTEGLE--KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHY 3068
            E +    GTE +   KIQ  E    KE G          P   T   D V   EG I H 
Sbjct: 4260 EESSSESGTEEVATVKIQEAEGGFIKEDG----------PMIHTPLVDTVS-EEGDIVHL 4308

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD-SGTYSCRATN 3127
              S+    +    + W++  K + +  + + +       L I    T D  G Y C A N
Sbjct: 4309 TTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALN 4364

Query: 3128 KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187
              G+   S KL  V ++    P     I+ +E +  G  A F C +     P+++ +W+ 
Sbjct: 4365 DSGKTATSAKLTVVKRAA---PVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFK 4418

Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
             G+ +  S +    S      L+I  TQ  D GEY C+A N+YG     AT+
Sbjct: 4419 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 4470



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 54/223 (24%), Positives = 92/223 (41%), Gaps = 16/223 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G   + +EW+ +GK + +S + +  +   +  L IL  +  D+GTY+ +  N  G++  +
Sbjct: 6656 GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCT 6715

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++  D++    P FT  ++N  G+  G S   EC V       + + W+H    +   
Sbjct: 6716 AVVDVSDRA--VPPSFTRRLKNTGGVL-GASCILECKV--AGSSPISVAWFHEKTKIVSG 6770

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD 3255
             + +T        L +    + D G Y C A N  G D  RA +             +P 
Sbjct: 6771 AKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQ----------EPP 6820

Query: 3256 SLAKIRE-LESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEG 3297
            S  K  E LE L G      S     PP  +   +   +LV+G
Sbjct: 6821 SFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG 6863



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 65/271 (23%), Positives = 115/271 (42%), Gaps = 36/271 (13%)

Query: 912  KTPIKDQ----ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            K P+ DQ    +++ EG +      ++  G   +R++WLK GR ++ S R +  F  G  
Sbjct: 9271 KPPVFDQHLTPVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFASGTA 9328

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             L ++ V   D+G Y C+A N  G  TT + +TI  K  +   ++               
Sbjct: 9329 VLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATK--------------- 9373

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGK--Q 1085
                  +  +    +P+ +       ++VE  +A F A+V    D    V+W   GK  Q
Sbjct: 9374 --KAAVDGRLFFVSEPQSI-------RVVEKTTATFIAKV--GGDPIPNVKW-TKGKWRQ 9421

Query: 1086 ITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID-TS 1144
            +    R+  +       L+I      DSG+Y  VA N  GE + + ++ V+ R   +   
Sbjct: 9422 LNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIE 9481

Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKS 1175
               R + +KT  +++    E    I E+ K+
Sbjct: 9482 GDLRAMLKKTPILKKGAGEEEEIDIMELLKN 9512



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 72/298 (24%), Positives = 124/298 (41%), Gaps = 16/298 (5%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIG 137
            ++ R  +   A F  K+ G+P P V WT+ K    + N+    +  Q GD + L I+   
Sbjct: 9388 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR--QLNQGGRVFIHQKGDEAKLEIRDTT 9445

Query: 138  PGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYT 197
              D G Y C A N++GE   +V +Q +                  +  ++  A   +   
Sbjct: 9446 KTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEID 9505

Query: 198  T-EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLR----EVSFRESITKRYVGESDVQI 252
              E  +      Y          DF+     + LL+    E + R  I +    E D + 
Sbjct: 9506 IMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKE 9565

Query: 253  STE----IDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGN-PRPRVTWFKNGQRLI 307
              E    I + L    P  + +   N  + +  DA F++ +  N P  +++W+K  ++L 
Sbjct: 9566 FEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLE 9625

Query: 308  NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
             S+K EI    +  TLRV+N Q  D G+Y L+   P+  I ++    +E   E ++QD
Sbjct: 9626 PSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC-GPH--IASAKLTVIEPAWERHLQD 9680



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/313 (24%), Positives = 127/313 (40%), Gaps = 39/313 (12%)

Query: 4410  PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
             P  F + ++   V E + A F  +   E    +KWYR    IK    ++     +   LI
Sbjct: 13749 PTEFVEHLEDQTVTEFDDAVFSCQLSREKAN-VKWYRNGREIKEGKKYKFEKDGSIHRLI 13807

Query: 4470  IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
             I+   ++D   +A   E+R    K  A L VEE         +P       Q++    G 
Sbjct: 13808 IKDCRLDDECEYACGVEDR----KSRARLFVEE---------IPVEIIRPPQDILEAPGA 13854

Query: 4530  LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
              V    ++   K ++V WL+N   V    +++++ E   + L I +  P+D G+Y  +A 
Sbjct: 13855 DVVFLAELNKDK-VEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAK 13913

Query: 4590  NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
             +   EAR   E   +         P+ K A+         +D +V  G+ +         
Sbjct: 13914 DK--EARAKLELAAA---------PKIKTAD---------QDLVVDVGKPLTMVVPYDAY 13953

Query: 4650  PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
             P    +W+K +   +P     +  TA++ + RI EA   D+G YK V  N  G+      
Sbjct: 13954 PKAEAEWFKEN---EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFIN 14010

Query: 4710  LKVTQ-PDQADNL 4721
             LKV   P    NL
Sbjct: 14011 LKVIDVPGPVRNL 14023



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 117/538 (21%), Positives = 220/538 (40%), Gaps = 83/538 (15%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            PQ ++ LQ +  +Q G+ A F A ++    P  ++ WYK+ + ++   +   + +    +
Sbjct: 3239 PQVLQELQPV-TVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L ++    EDA  YT  A N  G  ++T S   A+ S    ++  P+Q   +        
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYG--VATTS---ASLSVEVPEVVSPDQEMPV-------- 3342

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                               P   TP++D ++  EG  A F+ R   +  + L+V W    
Sbjct: 3343 -----------------YPPAIITPLQDTVT-SEGQPARFQCR---VSGTDLKVSWYSKD 3381

Query: 950  RPVEASS--RITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
            + ++ S   R+T F +     L I      D G YT  A NA+GQ +++ANL++   + I
Sbjct: 3382 KKIKPSRFFRMTQFEDT--YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESI 3439

Query: 1008 IAES-QHPGGLEKIQY-----------LEDAS-RYSKRTEEEVKITQKP----RFLGPLK 1050
            + E  +    +E  ++           L  A  + SK  E    +++ P    +F    +
Sbjct: 3440 LHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKE 3499

Query: 1051 GTNKIVEGQSAHFEARVEPQSDLTMTV--------EWYFNGKQITSANRIQTYHDFGYVA 1102
            GT  I   + ++ +  +   + L++TV        +W+FNG  +T +   +   D    +
Sbjct: 3500 GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHS 3559

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I   + ED G YT +A N  G+   SA + + ++          G  +       +K 
Sbjct: 3560 LIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG--------EGHKDTETESAVAKS 3611

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +E +          P F++ L    P+   + +        +G+P   V WF   + +  
Sbjct: 3612 LEKLG-----GPCPPHFLKELK---PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCT 3663

Query: 1223 GSRFKTYYDFGFVALDIIH-ATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDT 1279
               +   ++       I++     D+G Y  +A N LG +  +A + V+     +TDT
Sbjct: 3664 SVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 3721



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 52/192 (27%), Positives = 82/192 (42%), Gaps = 10/192 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F         +  G+ A     L   G   + + WF N K +  S+ +R  +     
Sbjct: 4663 PPSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVNSEA 4720

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I   K  DSG+YSC A N  G    S   E V K   + P F   ++  + ++ G +
Sbjct: 4721 ILDITDVKVEDSGSYSCEAVNDVGSDSCST--EIVIK---EPPSFIKTLEPADIVR-GTN 4774

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A  +C V        +I W+ + + +R S + +  S    V L+I    + D GEY C  
Sbjct: 4775 ALLQCEVSGTG--PFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 4832

Query: 3227 YNKYGEDFTRAT 3238
             N+ G+    AT
Sbjct: 4833 ANEVGKCGCMAT 4844



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 46/197 (23%), Positives = 86/197 (43%), Gaps = 6/197 (3%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + +S++ + P F++  +D +   G     +CRV+G     V WF +  +I      +   
Sbjct: 7659 VHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSF 7718

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +E+    L ++ +  SD+G+ TCVA N +G       L V E      P F +   ++ V
Sbjct: 7719 SENVC-TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEP-----PSFEQTPDSVEV 7772

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              G  +   +   GTP  ++ W K    ++P     I  +   + L++   +  ++  Y 
Sbjct: 7773 LPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYS 7832

Query: 563  CTAQNVAGSTATRARLY 579
            C   N AGS +    L+
Sbjct: 7833 CLVTNDAGSASCTTHLF 7849



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 99/506 (19%), Positives = 194/506 (38%), Gaps = 55/506 (10%)

Query: 71   PPIFEQIFKNARFAQGGNA-KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            P  F +  + ++  + G+A +   K+ G P   ++W      + E +K+ M + E T   
Sbjct: 5225 PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTA-- 5282

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
             L +  +G  D GEY C A+N+ G   CS  +  +               +     +  +
Sbjct: 5283 VLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAE 5342

Query: 190  AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESD 249
              GT  +        +   + + T   S   +K  TF    L  +   + +     GE  
Sbjct: 5343 VAGTPPF--------EITWFKDNTILRSGRKYK--TFIQDHLVSLQILKFVAAD-AGEYQ 5391

Query: 250  VQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
             +++ E+  S+         PP   +K  ++    G  A FQ  L G+    VTW K+  
Sbjct: 5392 CRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSD 5451

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
             +   +   +   +N  +L +   +    G Y   A+N  G    S  L+V+ P  +  +
Sbjct: 5452 EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPA-TITE 5510

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            +  S  +T       + +   +++  A  F      +++T G  +++   VT      + 
Sbjct: 5511 EAVSIDVTQGDPATLQVKFSGTKEITAKWFK---DGQELTLG--SKYKISVTDT--VSIL 5563

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
              I+  +            +SG +   + N    D G  +C AR           +NV+ 
Sbjct: 5564 KIISTEK-----------KDSGEYTFEVQN----DVGRSSCKAR-----------INVL- 5596

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
             + ++ P F ++   ++  +G  + L     G+    I W KD   I  + + +      
Sbjct: 5597 -DLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDN 5655

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
             + L+I + + +D+  Y C+A N AG
Sbjct: 5656 TAFLEISQLEGTDSGTYTCSATNKAG 5681



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 42/176 (23%), Positives = 83/176 (47%), Gaps = 7/176 (3%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            +D+++G  A  +     +G + +  +WF +G+ +    + +      + +L+I+ T+  D
Sbjct: 5515 IDVTQGDPATLQVKF--SGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKD 5572

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            SG Y+    N  G++    ++  +D      P FT  ++ ++ +K G     EC +V   
Sbjct: 5573 SGEYTFEVQNDVGRSSCKARINVLDLI--IPPSFTKKLKKMDSIK-GSFIDLEC-IVAGS 5628

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P + I+W+ + Q +  S + K         L+I+  +  DSG Y C A NK G +
Sbjct: 5629 HP-ISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHN 5683



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 67/289 (23%), Positives = 112/289 (38%), Gaps = 9/289 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  K     +G     E  + G+    + W +    +    KY   +++ T    
Sbjct: 5601 PPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTA--F 5658

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I Q+   D G YTC+A N+ G   CS ++  +                +    ++   
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALV 5718

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             GT   T +  +  +++   +G   S   D   DT     L      +S T      +DV
Sbjct: 5719 GGTAPMTIKWFKDNKELH--SGAARSVWKD---DTSTSLELFAAKATDSGTYICQLSNDV 5773

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
              +T    +L    PP+  +KP     L+ G    F+ Q++G P+ RV+W+ +G  +   
Sbjct: 5774 GTATS-KATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAI 5832

Query: 310  NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             KH I       T ++   +  +SG Y   A N  G    S  L V+ P
Sbjct: 5833 QKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEP 5881



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 59/243 (24%), Positives = 98/243 (40%), Gaps = 9/243 (3%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +S L N+   EG+++  EC++     PT  + W+  +  + S   ++ T       L I 
Sbjct: 946  VSGLKNVTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIR 1003

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEA---VEQAEEA 2893
              + EDSG +TC A N  G+ +TS  L     +    +T     K   E    VE  +  
Sbjct: 1004 EAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVV 1063

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
                           P   + I      +LVEG  +    QV    +P   + W  +G  
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVP 1121

Query: 2954 LEQGSRFKLT--SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011
            L  G R+K++     G   L +   +  D+G YT    NK GE   S+++   +   L+ 
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1181

Query: 3012 RTQ 3014
            ++Q
Sbjct: 1182 KSQ 1184



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 48/175 (27%), Positives = 72/175 (41%), Gaps = 7/175 (4%)

Query: 405  EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVV 463
            EG +      +T     EV W+  ++ +  D   K L +++  + L+I  V   D  G  
Sbjct: 4302 EGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEY 4358

Query: 464  TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
             C A N SG+TA   +L V+++    AP    +   L V  G            P  R  
Sbjct: 4359 VCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQ 4415

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            W K G  I  + +  I +    S+L+I R +  D   Y C A N  GS +  A L
Sbjct: 4416 WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 4470



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 3/125 (2%)

Query: 3826 VSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP F+ ++  S+ +   E  R  C++  K  P +++ W++N K L   +  R  +  
Sbjct: 4660 VREPPSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVN 4717

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
                LDI  V  EDSG Y C AVND G D     I  K+ P  I   +    ++ + AL 
Sbjct: 4718 SEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALL 4777

Query: 3945 QMEAT 3949
            Q E +
Sbjct: 4778 QCEVS 4782



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 58/222 (26%), Positives = 85/222 (38%), Gaps = 17/222 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG   + I WF N + I+ S + R  +     VL +      DSG Y C A N+ G    
Sbjct: 5251 TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHC 5310

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            S  +  V +S    P FT   + IE LK+               P  +I W+ +   +R 
Sbjct: 5311 S-SIVIVKES----PYFTKEFKPIEVLKE---YDVMLLAEVAGTPPFEITWFKDNTILRS 5362

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254
              + KT      V L I      D+GEY CR  N+ G     A +              P
Sbjct: 5363 GRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTL---------REPP 5413

Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
              + KI    SL+G      +T     P  +T ++D  ++ E
Sbjct: 5414 SFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITE 5455



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 50/180 (27%), Positives = 78/180 (43%), Gaps = 7/180 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F +        +G      C ++G P  EV W  + +Q+R+    KI  ++  + +L 
Sbjct: 7385 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKI-TSKHFDTSLH 7443

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            I N+  SD G   C A N+ G     C +   E      P+FV++ S  +   G+ V L 
Sbjct: 7444 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEP-----PRFVKKLSDTSTLIGDAVELR 7498

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   G     + W KD   +I   E  RI      +TL +   +AS++  Y C  +N AG
Sbjct: 7499 AIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAG 7558



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 47/196 (23%), Positives = 83/196 (42%), Gaps = 3/196 (1%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + + E+ L P F +  +D   T G    FDC ++G     V+W+ + + ++D  N +   
Sbjct: 8975 LTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSF 9034

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
             ++    L I     S +G  +C A N  G  +   RL + E +    P F  R + ++ 
Sbjct: 9035 LDN-TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN--PPFFDIRLAPVDA 9091

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              GE         GT   +++W KD   I    + +I     ++ L + +    D+  Y 
Sbjct: 9092 VVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYT 9151

Query: 563  CTAQNVAGSTATRARL 578
            C A N  G  +  A+L
Sbjct: 9152 CYAVNEVGKDSCTAQL 9167



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 94/396 (23%), Positives = 156/396 (39%), Gaps = 52/396 (13%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            ++   V E  +A  E +     +  +KWY  +  IK     Q     TK  L+I +    
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2510

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D   +  +     G  + + NL VE K +  RG           +++  T  Q V  + +
Sbjct: 2511 DEGPYKLIV----GRVETNCNLSVE-KIKIIRG----------LRDLTCTETQNVVFEVE 2555

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            ++ +  IDV W    K+++P  + KI      Y L +L     D GKY       AGE  
Sbjct: 2556 LSHSG-IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFY----AGENI 2610

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               +  V                 A   I +PL D+ VAE Q   F C+ V  P    +W
Sbjct: 2611 TSGKLTV-----------------AGGAISKPLTDQTVAESQEAVFECE-VANPDSKGEW 2652

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  K +  +   +      +  L I+    +D G+Y    Y  A   T +AKLKV    
Sbjct: 2653 LRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY---TYKVATSKT-SAKLKV---- 2704

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
              + +     L+++ V E Q A F  ++T      +QW++ G ++     + +  +G   
Sbjct: 2705 --EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIY 2762

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             L I N    D   +  R     G++  SA+L V++
Sbjct: 2763 SLRIKNCAIVDESVYGFR----LGRLGASARLHVET 2794



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 51/246 (20%), Positives = 102/246 (41%), Gaps = 16/246 (6%)

Query: 3056 DIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT 3115
            +++ ++ G  A  E ++   G   +  +W+ +G+ + AS + R  +   +  L+    + 
Sbjct: 4951 ELIQVTAGDPATLEYTV--AGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAEL 5008

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
             DSG Y+   +N+ G +        +D+     P FT  ++N++ + +G +   +C +  
Sbjct: 5009 HDSGQYTFEISNEVGSSSCETTFTVLDRDIA--PFFTKPLRNVDSVVNG-TCRLDCKI-- 5063

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
                 M++ W+ +G+ +  S R +     G   L+I     +D+G + CRA N  G    
Sbjct: 5064 AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSK-- 5121

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLV 3295
                      G  +    P  + K    + L G+     ST     P  I   +   +LV
Sbjct: 5122 -------DSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELV 5174

Query: 3296 EGQSAH 3301
             G S +
Sbjct: 5175 SGGSCY 5180



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 52/213 (24%), Positives = 91/213 (42%), Gaps = 9/213 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    KD+ +     +A +E  +   G + + + W+ +G  ++    ++T +   + 
Sbjct: 8042 PPFFARKLKDVHETLGFPVA-FECRI--NGSEPLQVSWYKDGVLLKDDANLQTSFVHNVA 8098

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L+IL T  +  G Y+C A+N  G A  S KL     S+ + P F         L  G+S
Sbjct: 8099 TLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL---SEHEVPPFFDLKPVSVDLALGES 8155

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              F+C V       +KI W  + + +R     K         L +      D+G+Y C A
Sbjct: 8156 GTFKCHV--TGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYA 8213

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAK 3259
             N  G+D   A +    +   +++ L+P  + K
Sbjct: 8214 SNIAGKDSCSAHLGVQ-EPPRFIKKLEPSRIVK 8245



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 87/400 (21%), Positives = 165/400 (41%), Gaps = 50/400 (12%)

Query: 4415  KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
             K +    VF  E A FE+E   EP    +W  +  P+  SPD +I     K ILI+    
Sbjct: 12682 KPLYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQ 12740

Query: 4475  VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
             +  +   +  A N    AK +ANL V+E         +P  F     +V V      + +
Sbjct: 12741 LGMTGEVSFQAAN----AKSAANLKVKE---------LPLIFITPLSDVKVFEKDEAKFE 12787

Query: 4535  TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
              +V+  +P    WLK  +++  D R +++++   ++++I  A  +D  KY    +  A +
Sbjct: 12788 CEVS-REPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKY----MFEAED 12842

Query: 4595  ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
                  + ++     K                + PLKD    E ++  F+ ++    +  V
Sbjct: 12843 KHTSGKLIIEGIRLK---------------FLTPLKDVTAKEKESAVFTVELSHDNI-RV 12886

Query: 4655  QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
             +W+K D+ +  ++   M      +++   +   +D    +  A   +      AKL V +
Sbjct: 12887 KWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSE----AKLTVLE 12942

Query: 4715  PDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
              D     P  T  L+D    E      + +I SK    ++W ++G  I  + +  +  +G
Sbjct: 12943 GD-----PYFTGKLQDYTGVEKDEVILQCEI-SKADAPVKWFKDGKEIKPSKNAVIKADG 12996

Query: 4774  NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                +L++    + D G +TC      G  +TS KL ++ +
Sbjct: 12997 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 13032



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 66/258 (25%), Positives = 108/258 (41%), Gaps = 17/258 (6%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            +++ EG     E  +      T  V W ++   +E+S      F  G   L I+     D
Sbjct: 952  VTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAED 1009

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ---HPGGLEKIQYLEDASRY---SKR 1032
            +G +TC A N  G  +TS  L +   ++   E+         E+ +++E        +  
Sbjct: 1010 SGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSL 1069

Query: 1033 TEEEVKITQK--PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN 1090
            TEE+    +   P F+       K+VEG S  F  +V    +    V W  +G  +T+  
Sbjct: 1070 TEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1126

Query: 1091 RIQTYHD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
            R +  ++   G   L I+   A+D+G YT+V RN  GE   SAS+  E    +   S   
Sbjct: 1127 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQE 1186

Query: 1149 GLYEK--TRHIEESKFVE 1164
             LY+   T  ++E K  E
Sbjct: 1187 MLYQTQVTAFVQEPKVGE 1204



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 166/768 (21%), Positives = 293/768 (38%), Gaps = 65/768 (8%)

Query: 3675 LEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
            LEE   ++  + I + +     F + IK N  + EG  V F C++   G P  +I W+ +
Sbjct: 1271 LEEDGEEKMAVDISESEAVESGFDLRIK-NYRILEGMGVTFHCKMS--GYPLPKIAWYKD 1327

Query: 3735 GRPFATGSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
            G+    G R     L D G  +L I  +   D G YT  A+N  G+A  + K+       
Sbjct: 1328 GKRIKHGERYQMDFLQD-GRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAP 1386

Query: 3793 IVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECR 3852
            +   + +P      +I+ L    +S +P         P  ++  +      S G R E  
Sbjct: 1387 LGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEET 1446

Query: 3853 VEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
             E + +   +  +                +D+  V   +   +    G+ I   VND+  
Sbjct: 1447 DESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQI---VNDYTH 1503

Query: 3913 DFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQP 3972
               K  I       +I+    P        + Q  A   + +  V LT +    V+ +  
Sbjct: 1504 ---KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRA--GRSSISVILTVE---AVEHQVK 1555

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLL-HKNRFTPIYDF-GY 4030
            P FV ++++       E ++ E ++   G+PN  + W  N   ++ HK     I    G 
Sbjct: 1556 PMFVEKLKNVNI---KEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE 1612

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT---GKPGIVYDSQLPKHMKSIEKI 4087
             A+       +DS  Y   A N  G D T+  +       +P       +P+     ++I
Sbjct: 1613 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1672

Query: 4088 R--EME-ASWQVTPEQVVE----ESKARCPPVFVSLPDAVTVEEGEWARFCCRVT--GHP 4138
               E+E    +   EQ  E    + + +  P F     ++ ++    A F CR+T  G P
Sbjct: 1673 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDP 1732

Query: 4139 KPRVMWLLNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXL 4197
               V WL +G  +   +R ++  + G    D       D+G I                L
Sbjct: 1733 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1792

Query: 4198 KVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGV-IDHRPELKPK 4256
             V     D + +++ +  P  +     QR E ELE+   E  +    GV  D + + KP 
Sbjct: 1793 IV----KDEKSLVEESQLP--EGRKGLQRIE-ELERMAHEGAL---TGVTTDQKEKQKPD 1842

Query: 4257 VIKEPE----TEWQQSVKRKKNEEY-YNKLQELENEQVIKES---RLR-ESTHQYAIPGD 4307
            ++  PE     E + +  R +   Y   K+    N Q+I++S   R+R +  H   I   
Sbjct: 1843 IVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDC 1902

Query: 4308 KVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQ 4367
            K       K  A+  E  ++   ++  Q+ +   +   R P+P        E HV +  +
Sbjct: 1903 KSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPR------PEFHVHEPGK 1956

Query: 4368 TQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK 4415
             Q EV   +++ R + +TET E+  K +  ER+    V      + +K
Sbjct: 1957 LQFEV---QKVDRPVDTTETKEVV-KLKRAERITHEKVPEESEELRSK 2000



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 11/193 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F +  K +     G+ A +  ++  TG   +   W  +G  +  S   +   A    
Sbjct: 4477 PPTFLSRPKSLTTFV-GKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWKISDAENKH 4533

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +LE+      D G YSC+A+NK+G      +L  +D     KP F   ++ ++   + + 
Sbjct: 4534 ILELSNLTIQDRGVYSCKASNKFGADICQAELIIID-----KPHFIKELEPVQSAIN-KK 4587

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             H EC V   +D  + + W  +GQ +      K   +     L+I   +  DSG YVC A
Sbjct: 4588 VHLECQV--DEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTA 4645

Query: 3227 YNKYGEDFTRATI 3239
             N+ G     AT+
Sbjct: 4646 SNEAGSSSCSATV 4658



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 42/183 (22%), Positives = 79/183 (43%), Gaps = 8/183 (4%)

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
            D+ + + W  +G+ +      +  +   +  LEI   K  DSGTY C A+N+ G +  S 
Sbjct: 4597 DRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSA 4656

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             +     +  + P F   +     +  G+SA   C +     P +++ W+ N + +  S 
Sbjct: 4657 TV-----TVREPPSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESN 4709

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDS 3256
             ++        +LDI   +  DSG Y C A N  G D     I    +   ++++L+P  
Sbjct: 4710 TVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI-VIKEPPSFIKTLEPAD 4768

Query: 3257 LAK 3259
            + +
Sbjct: 4769 IVR 4771



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/194 (26%), Positives = 87/194 (44%), Gaps = 13/194 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP FT   K + D  +G     E   I  G   + I+WF + + I AS + +  +     
Sbjct: 5601 PPSFTKKLKKM-DSIKGSFIDLEC--IVAGSHPISIQWFKDDQEISASEKYKFSFHDNTA 5657

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LEI   + TDSGTY+C ATNK G  + S  L     +  + P F   ++  +      +
Sbjct: 5658 FLEISQLEGTDSGTYTCSATNKAGHNQCSGHL-----TVKEPPYF---VEKPQSQDVNPN 5709

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV-SDFGFVVLDIAYTQNHDSGEYVCR 3225
               +   +      M I+W+ + + + HS   ++V  D     L++   +  DSG Y+C+
Sbjct: 5710 TRVQLKALVGGTAPMTIKWFKDNKEL-HSGAARSVWKDDTSTSLELFAAKATDSGTYICQ 5768

Query: 3226 AYNKYGEDFTRATI 3239
              N  G   ++AT+
Sbjct: 5769 LSNDVGTATSKATL 5782



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 50/190 (26%), Positives = 81/190 (42%), Gaps = 10/190 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAEI 3134
            G   M I+WF + K +  S   R+V+       LE+   K TDSGTY C+ +N  G A  
Sbjct: 5720 GTAPMTIKWFKDNKELH-SGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATS 5778

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L   +      P+F      +  L++GQS  FEC +     P +++ WY +G  +  
Sbjct: 5779 KATLFVKEP-----PQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITA 5831

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254
              +       G     I+  +  +SG YVC A N  G       +    +   ++  L+P
Sbjct: 5832 IQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELK-VKEPPTFIRELKP 5890

Query: 3255 DSLAKIRELE 3264
              + K  ++E
Sbjct: 5891 VEVVKYSDVE 5900



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 32/112 (28%), Positives = 60/112 (53%), Gaps = 2/112 (1%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            +D  + E I+   P FI +++      ++ V  EC+V+  ED K+ + W ++G+ LP G 
Sbjct: 4558 ADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVD--EDRKVTVTWSKDGQKLPPGK 4615

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
             Y+  ++    +L+I     +DSG Y+C A N+ G     AT++ ++ P  +
Sbjct: 4616 DYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFV 4667



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 53/200 (26%), Positives = 87/200 (43%), Gaps = 16/200 (8%)

Query: 365   DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
             D    Y  + + ++T  R+ ++   L  +F+   +D+ V EG+   F C ++      V 
Sbjct: 12476 DDEGVYTAEVEGKKTSARLFVTGIRL--KFMSPLEDQTVKEGETATFVCELSHEKM-HVV 12532

Query: 425   WFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             WF ND ++    +  +L++  G  H L +  VTL D   +    +  S  TA   +L V+
Sbjct: 12533 WFKNDAKLHT--SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSS-TA---QLKVL 12586

Query: 484   EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
             E +    P F  +       E + + L    V    P + W KDG  I+P+P+  I  DG
Sbjct: 12587 EAD----PYFTVKLHDKTAVEKDEITLKCE-VSKDVP-VKWFKDGEEIVPSPKYSIKADG 12640

Query: 544   GASTLDIPRAKASDAAWYQC 563
                 L I +A   D   Y C
Sbjct: 12641 LRRILKIKKADLKDKGEYVC 12660



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 60/237 (25%), Positives = 91/237 (38%), Gaps = 16/237 (6%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
            EG +   E  ++    PT  V WY++   I +S      F  G   L I    AED+G +
Sbjct: 956  EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013

Query: 844  TVRAVNKLGEAISTASIRVAA------RSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXX 897
            T  AVN+ G   ++  + V         +T   +    E++R++E               
Sbjct: 1014 TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1073

Query: 898  XXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR 957
                 P     P F T    Q  + EGG   F  ++   G+    V W K G P+    R
Sbjct: 1074 AG---PGEPAAPYFITKPVVQ-KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYR 1127

Query: 958  ITTFFN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
                +N   G   L I      DAG YT    N  G+ + SA+L      +++ +SQ
Sbjct: 1128 YKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 65/289 (22%), Positives = 116/289 (40%), Gaps = 10/289 (3%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F +  +N      G  + + K+ G+    VSW +    +   ++Y + + E  G  SL
Sbjct: 5040 PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE--GTASL 5097

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
             I ++   D G +TC A N  G    S  +  +                  +  ++    
Sbjct: 5098 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQ 5157

Query: 192  GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ 251
            G+   T    +  +++   +G     T +    + E  L++  S   + T +    S+V 
Sbjct: 5158 GSTPLTIRWFKGNKELV--SGGSCYITKEALESSLELYLVK-TSDSGTYTCKV---SNVA 5211

Query: 252  ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADA-QFQVQLSGNPRPRVTWFKNGQRLINSN 310
               E   +L    P    +K   S+L +  DA Q   +++G P  ++TWF N + +  S+
Sbjct: 5212 GGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESS 5271

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESP 358
            KH +    +   LR+ +    DSG Y   A+N  G    S  + V ESP
Sbjct: 5272 KHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 5320



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 7/188 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P FV+  Q +DV      +    V G     + WF +++++       +  +++   +L 
Sbjct: 5695 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTST-SLE 5753

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVL 510
            +     +DSG   C   N  G    +  L V E      P+F+++ S  L +R G+    
Sbjct: 5754 LFAAKATDSGTYICQLSNDVGTATSKATLFVKEP-----PQFIKKPSPVLVLRNGQSTTF 5808

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              +  GTP  R++W  DG  I    +  I    G +T  I  A+  ++  Y C A+N AG
Sbjct: 5809 ECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAG 5868

Query: 571  STATRARL 578
            + +    L
Sbjct: 5869 TASCSIEL 5876



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 55/276 (19%), Positives = 108/276 (39%), Gaps = 9/276 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+F          +      E +L G P   V W + K  L    KY +    +    S
Sbjct: 6443 PPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIA--SKNFHTS 6500

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            + I  +   D GEY C A+N+ G   C   ++ +                     ++   
Sbjct: 6501 IHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASI 6560

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITK-RYVGESD 249
             G Q    +  ++ ++V   +     +  +  V T ++      +  + I + +  G  +
Sbjct: 6561 EGAQPIFVQWLKEKEEVIRESENIRITFVE-NVATLQFAKAEPANAGKYICQIKNDGGME 6619

Query: 250  VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
              ++T     L  + P  I +K     +  G     + +++G P   V W+K+G+ L +S
Sbjct: 6620 ENMAT-----LMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSS 6674

Query: 310  NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             KH+    +  ++LR+ + ++ D+G YT   +N  G
Sbjct: 6675 QKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVG 6710



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 10/203 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVY 3101
            T + P FT   + +V + EG  A +EA +  +G     + WF +G+ I  S    ++  +
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
            + G   L I      +SG YS +ATN  GQA  + +L  + K++   P F   +Q++  +
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMT-V 115

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            + G     +  V  +  P +K  +Y +G  ++ S   +   +     L IA     DSG 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGT 173

Query: 3222 YVCRAYNKYGEDFTRATINCYGK 3244
            Y   A N  G   + A +   G+
Sbjct: 174  YSVNATNSVGRATSTAELLVQGE 196



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 35/116 (30%), Positives = 55/116 (47%)

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            V +    +VT  A++             ++ L+++ V EG+    +  I+    PT+ W 
Sbjct: 918  VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 977

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            RE   I  + DFQ+  +   A L+I   + ED+G FTC A   AG V TS  L V+
Sbjct: 978  REDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 68/292 (23%), Positives = 112/292 (38%), Gaps = 9/292 (3%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            E  PP F    K+     G  AKF   + G P     W +  A L     + +   E   
Sbjct: 4474 EAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKH 4533

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVE 187
             + L    +   D G Y+C A N++G  IC   +                   +    +E
Sbjct: 4534 ILEL--SNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLE 4591

Query: 188  HKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247
             +    +  T   S+  QK+    G D+    + K+ T E  L +    ++S T      
Sbjct: 4592 CQVDEDRKVTVTWSKDGQKLP--PGKDYKICFEDKIATLEIPLAK---LKDSGTYVCTAS 4646

Query: 248  SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQ-EGADAQFQVQLSGNPRPRVTWFKNGQRL 306
            ++   S+    ++    PP   +K   S L   G  A+   +L G+P  +VTWFKN + L
Sbjct: 4647 NEAG-SSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKEL 4705

Query: 307  INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
              SN   +   ++   L + + +  DSG Y+  A N  G    S  + ++ P
Sbjct: 4706 SESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP 4757



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 41/157 (26%), Positives = 65/157 (41%), Gaps = 8/157 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG   + + W  +G  I  S +   V      +LEIL +   D+G YSC   N+ G+   
Sbjct: 6937 TGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVC 6996

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               +  +     + P F T ++ +E    G S   +C V     P++ + WY     +R 
Sbjct: 6997 GALVSTL-----EPPYFVTELEPLEAAV-GDSVSLQCQV--AGTPEITVSWYKGDTKLRP 7048

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +   +T        L       +DSGEY C+A N  G
Sbjct: 7049 TPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIG 7085



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 4/99 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V + P F +  H IET++G +VHLEC LQ  G     V W+ + + +++G +++   E
Sbjct: 8320 LKVKEPPIFRKKPHPIETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSE 8377

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGE--AVTSCALR 1401
                ++ +L+V   D G Y C+ATN +G    V S AL+
Sbjct: 8378 NFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 8416



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 44/148 (29%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            SGE + E +    SD      IV   P F  + K   V +   V     V     P   I
Sbjct: 5294 SGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGT--PPFEI 5351

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             W+++  +L SG +Y+T      VSL IL   A D+GEY CR  N+ G     A ++ ++
Sbjct: 5352 TWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLRE 5411

Query: 3924 LPDIILQNQVPRGMKRSEALTQMEATIK 3951
             P  I + +    ++   A  Q  AT+K
Sbjct: 5412 PPSFIKKIESTSSLRGGTAAFQ--ATLK 5437



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 44/187 (23%), Positives = 77/187 (41%), Gaps = 6/187 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F+K  +      G    F   + G     VTW  +  +I +D N ++   E+   +L 
Sbjct: 5413 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF-ENNVASLY 5471

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            ++ + +   G   C A+N +G       L+V E   +      E   +++V +G+P  L 
Sbjct: 5472 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIT-----EEAVSIDVTQGDPATLQ 5526

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             +  GT      W KDG  +    + +I      S L I   +  D+  Y    QN  G 
Sbjct: 5527 VKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGR 5586

Query: 572  TATRARL 578
            ++ +AR+
Sbjct: 5587 SSCKARI 5593



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 3/132 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875
            SD+     +V+ PPKF+ +++ S  V+  +  R EC++     P++R+ W+RN   LP+ 
Sbjct: 6337 SDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGS--PEIRVVWFRNEHELPAS 6394

Query: 3876 HRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
             +YR  +      + +  +  EDSG++IC A N  G       +  K+ P       +  
Sbjct: 6395 DKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVE 6454

Query: 3936 GMKRSEALTQME 3947
             +K +E   + E
Sbjct: 6455 TLKNAEVSLECE 6466



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 2/103 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F  + K H +E  +G       E +  P   + WY++ + L SG +Y+ + +  
Sbjct: 8322 VKEPPIF--RKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENF 8379

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
              S+ IL V A D GEY C+A ND G D    +I+ K  P  +
Sbjct: 8380 LTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFV 8422



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 40/158 (25%), Positives = 67/158 (42%), Gaps = 8/158 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG   + + W  NG  +  S R          +LEI  +   D+G Y+C   N  G+   
Sbjct: 8819 TGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSC 8878

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            S ++  +     + P F   ++ ++ +  G SA  +C +     P++ + WY     +R 
Sbjct: 8879 SAQILIL-----EPPYFVKQLEPVK-VSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRP 8930

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            +T  K         L       +DSGEY+C+A N  GE
Sbjct: 8931 TTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGE 8968



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 85/402 (21%), Positives = 160/402 (39%), Gaps = 50/402 (12%)

Query: 4415  KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
             K ++   ++E E A F+ E     +P  +W  +   ++ SP  +I     K  L +R+V 
Sbjct: 12328 KPIEDVTIYEKESASFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLRKVK 12386

Query: 4475  VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
             ++ +      A N    A  +A L V+E         +   F +  ++V V   +  R +
Sbjct: 12387 LDQAGEVLYQALN----AITTAILTVKE---------IELDFAVPLKDVTVPERRQARFE 12433

Query: 4535  TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
               +T  +  +V W K      PDI    ++    + ++         GK   + IN   +
Sbjct: 12434 CVLT--REANVIWSKG-----PDI----IKSSDKFDIIA-------DGKKHILVIN---D 12472

Query: 4595  ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             ++ D E V +      K   +        + + PL+D+ V EG+   F C++  + +  V
Sbjct: 12473 SQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVV 12532

Query: 4655  QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
              W+K D  +  S+   +S     + L + E   +D    K         ++  A+LKV +
Sbjct: 12533 -WFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKA----QVKELSSTAQLKVLE 12587

Query: 4715  PDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
              D     P  T  L D    E      K +++  +   ++W ++G  I  +P + +  +G
Sbjct: 12588 AD-----PYFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSPKYSIKADG 12640

Query: 4774  NNAVLLIGNTYEEDTGTFTCRATT--AAGQVETSAKLVVKSK 4813
                +L I     +D G + C   T      V   A+L+   K
Sbjct: 12641 LRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEK 12682



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 92/397 (23%), Positives = 156/397 (39%), Gaps = 53/397 (13%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            +K +    V E ++A FE E    P    +W R+   +  + + +  +   K  LII   
Sbjct: 2623 SKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAAT 2681

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             ++D   +      +  T+K SA L VE  +              T +N+ VT  Q    
Sbjct: 2682 KLDDIGEYTY----KVATSKTSAKLKVEAVK-----------IKKTLKNLTVTETQDAVF 2726

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              ++T      V W+KNG  ++ + +  I  +   Y+L I      D   Y         
Sbjct: 2727 TVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGA 2786

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR   E V                     +II+  KD    E   + F   +    +P 
Sbjct: 2787 SARLHVETV---------------------KIIKKPKDVTALENATVAFEVSVSHDTVP- 2824

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            V+W+  +  IKPS   ++      + L +    P D G+Y  V     G++   AKL V 
Sbjct: 2825 VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFV- 2879

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
                 + L     +++I V E + A F+ +++    P++ WL+ G  I  +  F+++ +G
Sbjct: 2880 -----ETLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG 2933

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                L+I NT  ED+  +    T   G  + SA L V
Sbjct: 2934 KLHQLIIMNTSTEDSAEY----TFVCGNDQVSATLTV 2966



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 83/405 (20%), Positives = 153/405 (37%), Gaps = 68/405 (16%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+ + +++  TV+  +  RF   +  +  PK  I WY+  +LL +G + +         
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPK--ISWYKEEQLLSTGFKCK--------- 3286

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
                  +  D  EY    +  F ED   A  +C+   D         G+  + A   +E 
Sbjct: 3287 ------FLHDGQEYTLLLIEAFPED--AAVYTCEAKNDY--------GVATTSASLSVEV 3330

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
                   EV   + ++       PP  +T +Q  T   E +  +F+C+   V   ++KV 
Sbjct: 3331 P------EVVSPDQEM----PVYPPAIITPLQD-TVTSEGQPARFQCR---VSGTDLKVS 3376

Query: 4009 WFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W+   K +   +RF  +  F     +     YPED G Y   A+N  G   + A +    
Sbjct: 3377 WYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435

Query: 4068 KPGIVYD---SQLPKHMKSIE----------------KIREMEASWQVTPEQVV-----E 4103
               I+++    ++   MK                   ++ ++  + ++  E  V     +
Sbjct: 3436 PESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFD 3495

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
              K    P+F+       +  G+ A     V G PKP++ W  NG  +   + YK  +DG
Sbjct: 3496 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3555

Query: 4164 MYH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR 4207
              H   I  T+  D G+   +             LK+  + + ++
Sbjct: 3556 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK 3600



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP+F    +      +G+    E  +  +G   + + WF N   +  S +    +   + 
Sbjct: 7290 PPKFVKKLEASKVAKQGESIQLECKI--SGSPEIKVSWFRNDSELHESWKYNMSFINSVA 7347

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I      DSG Y C A N  G A  S  L     +    P FT     +  LK G  
Sbjct: 7348 LLTINEASAEDSGDYICEAHNGVGDASCSTAL-----TVKAPPVFTQKPSPVGALK-GSD 7401

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               +C +     P  ++ W  + + +R+S + K  S      L I   +  D GEY C+A
Sbjct: 7402 VILQCEI--SGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKA 7459

Query: 3227 YNKYGED 3233
             N+ G D
Sbjct: 7460 TNEVGSD 7466



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 87/395 (22%), Positives = 170/395 (43%), Gaps = 53/395 (13%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            ++V++ P F   L ++E V G    L+C++   G   +R+ W+     +++   ++  ++
Sbjct: 7941 VSVLEPPYFIEPLEHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFK 7998

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK-----------KDLILESQ 1413
             +  +L +  V   D G Y+C+A N +G AV S A+ VI +           KD+     
Sbjct: 7999 NNVASLVINKVDHSDVGEYSCKADNSVG-AVASSAVLVIKERKLPPFFARKLKDVHETLG 8057

Query: 1414 HPSGLE-KIQYLE--DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQ-HV-HFECKL 1468
             P   E +I   E    S YK   ++ +   ++  FV    +++ +   Q H+  + C  
Sbjct: 8058 FPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSA 8117

Query: 1469 EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
                 SN       + + +   H   P  D   V+   +DL   +SG + C   ++ GT 
Sbjct: 8118 -----SNPLGTASSSAKLILSEHEVPPFFDLKPVS---VDLALGESGTFKC---HVTGTA 8166

Query: 1529 EVSCRLTCRSTTDIVRS--------TQNEAGLEQIQVLE-DRSKY--HRTDMVDEVTTQA 1577
             +  ++T       +R          +N A L  ++V + D  +Y  + +++  + +  A
Sbjct: 8167 PI--KITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSA 8224

Query: 1578 PICTTS----LKNVE----IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629
             +        +K +E    +K+ +   +E ++       +KV WY +   ++  S+F  +
Sbjct: 8225 HLGVQEPPRFIKKLEPSRIVKQDEFTRYECKI--GGSPEIKVLWYKDETEIQESSKFRMS 8282

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                   L++ +   EDSG YTC A NA G A +S
Sbjct: 8283 FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSS 8317



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 37/111 (33%), Positives = 58/111 (52%), Gaps = 3/111 (2%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            + V + PRFI +L     + + +   YEC+I   P+  ++V WY +   +Q   ++R S 
Sbjct: 8226 LGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPE--IKVLWYKDETEIQESSKFRMSF 8283

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
                A L++  +  EDSG+YTC+A N  G A SS  L V+ +  I R   H
Sbjct: 8284 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK-EPPIFRKKPH 8333



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 71/276 (25%), Positives = 117/276 (42%), Gaps = 33/276 (11%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  PVF Q L+ P  VSEG+ + L C ++  G   +R++W   GR +    R    +  G
Sbjct: 9270 KKPPVFDQHLT-PVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFASG 9326

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLED 1293
               L++     AD+G+Y  +A N  GS  T + V + ++  +   T+             
Sbjct: 9327 TAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKK------------ 9374

Query: 1294 AARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK-- 1351
            AA     V   +  +  PQ      +I  VE T      ++   GD    V+W   GK  
Sbjct: 9375 AA-----VDGRLFFVSEPQ------SIRVVEKTTATFIAKVG--GDPIPNVKW-TKGKWR 9420

Query: 1352 PIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV-IAKKDLIL 1410
             +  G R     + D   L++      DSG+Y C A N+ GE  ++  L+V   KK   +
Sbjct: 9421 QLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKI 9480

Query: 1411 ESQHPSGLEKIQYL-EDTSRYKKTDIIDESVTIKPR 1445
            E    + L+K   L +     ++ DI++    + P+
Sbjct: 9481 EGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPK 9516



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 78/342 (22%), Positives = 121/342 (35%), Gaps = 19/342 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN-K 470
            + RV   P P   +   D    D Y  +  V       + IT  T+ +        R  K
Sbjct: 868  ETRVRAEPTPLPQFPFADTP--DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAK 925

Query: 471  SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530
              ETA   R+    +  V  P  V     + V EGE V L     G P+P +TW ++   
Sbjct: 926  VTETA---RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQ 982

Query: 531  IIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQ 590
            I  + + +I    G + L I  A A D+  + C+A N AG+ +T   L           +
Sbjct: 983  IESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL---AVQVSEEFE 1039

Query: 591  KRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAME 650
            K                       +           PGE       P FI        +E
Sbjct: 1040 KETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEP----AAPYFITKPVVQKLVE 1095

Query: 651  GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--RFGYISLDMLSLNIQDSGE 708
            GG + F  ++   G+P   + W K+G  +    R+   +  + G   L +      D+GE
Sbjct: 1096 GGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1153

Query: 709  YTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQL 750
            YT    +  G  ET A   +   A  E   +  + + Y  Q+
Sbjct: 1154 YTIVVRNKHG--ETSASASLLEEADYELLMKSQQEMLYQTQV 1193



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 36/106 (33%), Positives = 54/106 (50%), Gaps = 2/106 (1%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V + P+FI + +    L  GQS  +EC+I     P +RV WY +G  + +  ++  S   
Sbjct: 5784 VKEPPQFIKKPSPVLVLRNGQSTTFECQITG--TPKIRVSWYLDGNEITAIQKHGISFID 5841

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
            G A   I     E+SG Y C+A N+ G A  SI L V+   + IR+
Sbjct: 5842 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE 5887



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 66/293 (22%), Positives = 121/293 (41%), Gaps = 16/293 (5%)

Query: 71   PPIFEQIFKNARFA-QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP F +  + ++ A QG + + E K+ G+P   VSW R  + L E  KY+M +      V
Sbjct: 7290 PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF---INSV 7346

Query: 130  SLL-IKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH 188
            +LL I +    D G+Y C A N  G+A CS  +  +               +     ++ 
Sbjct: 7347 ALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQC 7406

Query: 189  KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEY-RLLREVSFRESITKRYVGE 247
            +  GT  +     +  ++V         ++  FK+ +  +   L  ++   S    Y  +
Sbjct: 7407 EISGTPPFEVVWVKDRKQV--------RNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 7458

Query: 248  SDVQISTE-IDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN-GQR 305
            +  ++ ++    S+    PP+  +K  ++    G   + +  + G     V W K+ G+ 
Sbjct: 7459 ATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEV 7518

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            +  S    I    N  TL++ + + S+SG Y    +N  G    S  L V  P
Sbjct: 7519 IRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEP 7571



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 77/352 (21%), Positives = 142/352 (40%), Gaps = 45/352 (12%)

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
            KQ+Q+E     EI  +I  +E  E E +       ++  +  ++P    K ++   V + 
Sbjct: 9541 KQSQEEETHRLEI-EEIERSERDEKEFEELVS--FIQQRLSQTEPVTLIKDIENQTVLKD 9597

Query: 4426 EQARFEVEFD-GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484
              A FE++     P   + WY+    ++ S  F+I     +  L ++   ++D   +  V
Sbjct: 9598 NDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLV 9657

Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
                 G    SA L V E           P++    Q+V +  GQ   +  + +    + 
Sbjct: 9658 C----GPHIASAKLTVIE-----------PAWERHLQDVTLKEGQTCTMTCQFS-VPNVK 9701

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC--VAINSAGEARCDAECV 4602
              W +NG+ ++P  R+K   E   + L I +   +D G+Y C    + ++ E R +AE  
Sbjct: 9702 SEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAE-- 9759

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
                               P +  + +++ +V+E Q+  F C+ V      V WYKG   
Sbjct: 9760 -------------------PIQFTKRIQNIVVSEHQSATFECE-VSFDDAIVTWYKGPTE 9799

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA-YNSAGRVTVAAKLKVT 4713
            +  S+ +        + + I    P+DEG Y  +A     G     A+L +T
Sbjct: 9800 LTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLT 9851



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 8/161 (4%)

Query: 357  SPTESYVQDQRSQYITDTQQRETEE-RIE--ISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
            S T + V+++R + +   + + TE  R+   +      P  V   ++  V EG+    +C
Sbjct: 905  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
             ++G P P VTW+  D QI    + +I   +SG   LMI      DSG  TC A N++G 
Sbjct: 965  HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023

Query: 474  TAFQCRL--NVIEKEQVVAPKFVERFSTLNVR--EGEPVVL 510
             +  C L   V E+ +       E+F+T   R  E   VV+
Sbjct: 1024 VSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVM 1064



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 3/101 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F +PL N   V  G    L+C++   G   MRV WF +G+ +    R++  +  G  +
Sbjct: 5040 PFFTKPLRNVDSVVNG-TCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT 1277
            L+II     D G +T RA N +GS  +S  + V E    VT
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVT 5137



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 38/140 (27%), Positives = 80/140 (57%), Gaps = 5/140 (3%)

Query: 1801 FVQSKASLQL-ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
            FV++ A+LQ  +++  +A + I Q+++    +  E++   +   P  I +  GP  ++ G
Sbjct: 6588 FVENVATLQFAKAEPANAGKYICQIKNDGGME--ENMATLMVLEPAVIVEKAGPMTVTVG 6645

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            ++   EC++   P+  + VEWY +GK+L S  +++ S     ++L IL+V  +D+G YT 
Sbjct: 6646 ETCTLECKVAGTPE--LSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTF 6703

Query: 1920 KAINNLGQAVSSIRLNVQSK 1939
            +  NN+G++  +  ++V  +
Sbjct: 6704 QVQNNVGKSSCTAVVDVSDR 6723



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 2/102 (1%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            +++V + P+F+ +L       +G+S   EC+I   P+  ++V W+ N   L    +Y  S
Sbjct: 7284 QLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPE--IKVSWFRNDSELHESWKYNMS 7341

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
                 A L I     EDSG+Y C+A N +G A  S  L V++
Sbjct: 7342 FINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 7383



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 94/442 (21%), Positives = 170/442 (38%), Gaps = 34/442 (7%)

Query: 3778 SATTTAKITCSAKRDI--VLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQ 3835
            S +    IT + K  I  +LES +        + E E G+  D  +    V  PP FI  
Sbjct: 7895 SQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQ--DICEALVSVLEPPYFIEP 7952

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            ++       E    +C+V+    P++RI WY+    L S   Y+  +     SL I  V 
Sbjct: 7953 LEHVEAVIGEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVD 8010

Query: 3896 AEDSGEYICRAVNDFGEDFTKATISCK--KLPDIILQ--NQVPRGMKRSEALTQMEATIK 3951
              D GEY C+A N  G   + A +  K  KLP    +    V   +    A  +      
Sbjct: 8011 HSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARKLKDVHETLGFPVAF-ECRINGS 8069

Query: 3952 KYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLV--EMETTKFECQLA-PVGDPNMKVE 4008
            +     +  +  L   D      FV  + +   L   +    ++ C  + P+G  +    
Sbjct: 8070 EPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASS--- 8126

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
               + K +L ++   P +D   V+++       +SG + C  T    +  T A      +
Sbjct: 8127 ---SAKLILSEHEVPPFFDLKPVSVDLAL---GESGTFKCHVTGTAPIKITWAKDNREIR 8180

Query: 4069 PGIVYDSQLPKHMKSIEKIREMEA-SWQVTPEQVVEESKARC--------PPVFV-SLPD 4118
            PG  Y   L ++  ++  ++  +  + Q T        K  C        PP F+  L  
Sbjct: 8181 PGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPPRFIKKLEP 8240

Query: 4119 AVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDT 4177
            +  V++ E+ R+ C++ G P+ +V+W  +   I   S++++++ D +   ++      D+
Sbjct: 8241 SRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDS 8300

Query: 4178 GKIEVIXXXXXXXXXXXXXLKV 4199
            G                  LKV
Sbjct: 8301 GDYTCEAHNAAGSASSSTSLKV 8322



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 1/121 (0%)

Query: 451   MITNVTLSDSGVVTCVARNKSGET-AFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
             +ITN+T  +  +   VA N+ G +      + ++ K+ V+ P     FS+ +V+ G+ + 
Sbjct: 24116 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 24175

Query: 510   LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +     G P P ITW KDG+P+     + +      +TL I      D   Y  T  NV 
Sbjct: 24176 IEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVV 24235

Query: 570   G 570
             G
Sbjct: 24236 G 24236



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 62/296 (20%), Positives = 115/296 (38%), Gaps = 22/296 (7%)

Query: 71   PPIFEQIFKNARFAQGGNA-KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP F +  + ++  + G++ + E K+ G+P   V W R +  L   +KY M + +    +
Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVI 6408

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
             +    +   D G++ C A+N  G   CS  +  +               ++   ++E +
Sbjct: 6409 QM--NNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECE 6466

Query: 190  AYGTQGYTT------EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
              GT  +         Q R ++K    +   H+S     VDT       ++       + 
Sbjct: 6467 LSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDT------SDIGEYHCKAQN 6520

Query: 244  YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             VG SD  + T     +    PP+   K  +  +  G  A+ Q  + G     V W K  
Sbjct: 6521 EVG-SDTCVCT-----VKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEK 6574

Query: 304  QRLINSNKHEIIT-THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            + +I  +++  IT   N  TL+    + +++G Y    +N  G       L V  P
Sbjct: 6575 EEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLEP 6630



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 6/195 (3%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G+ P F  +    VD   G+ A +E  +  TG Q + + W  + + I +  + +  Y   
Sbjct: 9076 GKNPPFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLEN 9133

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +L     DSG Y+C A N+ G+   + +L    K +   P FT  +       +G
Sbjct: 9134 SAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI--KERLIPPSFTKRLSETVEETEG 9191

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
             S   E  V       + + WY N   ++ ++  +       +VL +     +D+G Y C
Sbjct: 9192 NSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTC 9249

Query: 3225 RAYNKYGEDFTRATI 3239
            +  N  G     ++I
Sbjct: 9250 KVSNDAGSALCTSSI 9264



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 82/307 (26%), Positives = 134/307 (43%), Gaps = 46/307 (14%)

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
            ++ K+ E   A F+ ++S  P   V W K+ Q L  +++ +I        L + +T+ SD
Sbjct: 3065 KDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 3123

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
            +G YT++A    G  V++  L VE                D + R  ++ +++ EK  A 
Sbjct: 3124 AGKYTVVA----GGNVSTAKLFVEG--------------RDVRIRSIKKEVQVIEKQRAV 3165

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
               +V +D DV              +   E+ + + +R       HK +V E   H + I
Sbjct: 3166 VEFEVNED-DVDAHWY---------KDGIEINFQVQER-------HKYVV-ERRIHRMFI 3207

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +    SD+G  T VA RN+S  T +   +N  E  QV+     +    + V+ G+P    
Sbjct: 3208 SETRQSDAGEYTFVAGRNRSSVTLY---VNAPEPPQVL-----QELQPVTVQSGKPARFC 3259

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            A   G P P+I+W K+   +    + +   DG   TL +  A   DAA Y C A+N  G 
Sbjct: 3260 AVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGV 3319

Query: 572  TATRARL 578
              T A L
Sbjct: 3320 ATTSASL 3326



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 29/92 (31%), Positives = 52/92 (56%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F  PL++V ++  G    + +I   G   M++ W K+G+ I AS R+   F  G  SL
Sbjct: 5040 PFFTKPLRNVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 5097

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +++ +++ D+G +TCRA ++ G  ++   L V
Sbjct: 5098 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 5129



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 61/246 (24%), Positives = 110/246 (44%), Gaps = 42/246 (17%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            ++V +    +    +I+  +G    L+ +    G + +  +WF +G+ +  G +++ +  
Sbjct: 5500 LSVKEPATITEEAVSIDVTQGDPATLQVKFS--GTKEITAKWFKDGQELTLGSKYKISVT 5557

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYL 1424
                 L ++S   +DSG YT +  N +G   +SC  R I   DLI+    PS  +K+   
Sbjct: 5558 DTVSILKIISTEKKDSGEYTFEVQNDVGR--SSCKAR-INVLDLIIP---PSFTKKL--- 5608

Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484
                  KK D      +IK  F+     +E ++ G H        P++     ++WFK+ 
Sbjct: 5609 ------KKMD------SIKGSFI----DLECIVAGSH--------PIS-----IQWFKDD 5639

Query: 1485 QPVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            Q ++   +++   HD     L+I  L   DSG YTC A N  G ++ S  LT +     V
Sbjct: 5640 QEISASEKYKFSFHD-NTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFV 5698

Query: 1544 RSTQNE 1549
               Q++
Sbjct: 5699 EKPQSQ 5704



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 76/360 (21%), Positives = 145/360 (40%), Gaps = 39/360 (10%)

Query: 3825 IVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            +VST  PP F+T+++       + V  +C+V     P++ + WY+    L     YRT +
Sbjct: 6999 LVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYF 7056

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEA 3942
                 +L    V   DSGEY C+A N  G   +K      ++ +  L     R +K  E 
Sbjct: 7057 TNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVF---RIQERQLPPSFARQLKDIEQ 7113

Query: 3943 LTQMEATI------KKYTSEVYLTEDDLYDVDKKQPPRFVTQIQS----QTSLVEMETTK 3992
               +  T+             +  +  L   D+     FV  + +    QT L    + +
Sbjct: 7114 TVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDL--SHSGQ 7171

Query: 3993 FECQLA-PVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRAT 4051
            + C  + P+G  +       + +    + + +P +D   V+++   V   +S ++ C  T
Sbjct: 7172 YSCSASNPLGTASS------SARLTAREPKKSPFFDIKPVSID---VIAGESADFECHVT 7222

Query: 4052 NLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA-SWQVTPEQVVEESKARC- 4109
                M  T +      +PG  Y      +   +  ++  +  S Q T +   +  K  C 
Sbjct: 7223 GAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCS 7282

Query: 4110 -------PPVFVSLPDAVTV-EEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
                   PP FV   +A  V ++GE  +  C+++G P+ +V W  N + +    +Y +++
Sbjct: 7283 AQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF 7342



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 60/279 (21%), Positives = 107/279 (38%), Gaps = 13/279 (4%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            +PP+F Q        +G +   + ++ G P   V W + +  +    K+ +    +  D 
Sbjct: 7383 APPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKI--TSKHFDT 7440

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
            SL I  +   D GEY C A N+ G   CS  ++ +                 + + VE +
Sbjct: 7441 SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTL--IGDAVELR 7498

Query: 190  AY--GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247
            A   G Q  +    +   +V   +     S  D          L+  S   S + +Y+ +
Sbjct: 7499 AIVEGFQPISVVWLKDRGEVIRESENTRISFID------NIATLQLGSPEASNSGKYICQ 7552

Query: 248  SDVQIST-EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
                    E    L  + P +I +KP    +  G     +  ++G P     WFK+G+ L
Sbjct: 7553 IKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGREL 7612

Query: 307  INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               +KH I   +   +L++   + SD G Y+   +N  G
Sbjct: 7613 SADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVG 7651



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 35/105 (33%), Positives = 56/105 (53%), Gaps = 2/105 (1%)

Query: 255  EIDRS-LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE 313
            E D S L  +  P    KP + K  EG  A+F +++ G P P   WF +GQ+++N   H+
Sbjct: 1445 ETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK 1504

Query: 314  IITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            ++   + T +L +     SDSG +T++A+N  G    S  L VE+
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1549



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 3/93 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP FT ++K+   +  G  V  +C+V   G P + + WFH G   ++G +  T       
Sbjct: 8608 PPSFTRKLKETNGL-SGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTC 8664

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            AL ++ +   D+G+YTC ATN  GS   +A +T
Sbjct: 8665 ALTVNMLEESDSGDYTCIATNMAGSDECSAPLT 8697



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 48/196 (24%), Positives = 81/196 (41%), Gaps = 13/196 (6%)

Query: 373   DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
             D Q    +    +  K      ++  +D  VT G+   FDC ++    P V W++  +++
Sbjct: 13104 DFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKL 13162

Query: 433   RDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
                 + K++    G  H L + +V L D+G V   A++      F+   N+  KE  V  
Sbjct: 13163 EP--SDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD------FKTHANLFVKEPPV-- 13212

Query: 492   KFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551
             +F +      V EG   VL    V     ++ W K+G  I+ + +  I  DG    L I 
Sbjct: 13213 EFTKPLEDQTVEEGATAVLECE-VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIH 13271

Query: 552   RAKASDAAWYQCTAQN 567
                  D   Y C A++
Sbjct: 13272 DCTPEDIKTYTCDAKD 13287



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 39/121 (32%), Positives = 56/121 (46%), Gaps = 4/121 (3%)

Query: 4596  RCDAECVVSLPATKDKPKPQT-KAANAPPEIIEPLKDK---IVAEGQAIEFSCKIVGKPL 4651
             R  A   V++    +   P T  A N PP I   +  K    V  G  +     + GKP+
Sbjct: 20192 RAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPM 20251

Query: 4652  PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
             PTV W K   L+KP++  +M+   +  TL +     +D GDY   A NS+G  +   KLK
Sbjct: 20252 PTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLK 20311

Query: 4712  V 4712
             V
Sbjct: 20312 V 20312



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 32/146 (21%), Positives = 73/146 (50%), Gaps = 3/146 (2%)

Query: 1258 LGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT-VMQAPQFSRA 1316
            LGS +  ++   +    I++  + +      ++  D  R + + R ++  ++  P F++ 
Sbjct: 5548 LGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKK 5607

Query: 1317 LHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVY 1376
            L  +++++G+ + LEC +   G   + ++WF + + I    +++ ++  +   L++  + 
Sbjct: 5608 LKKMDSIKGSFIDLECIV--AGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLE 5665

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRV 1402
              DSG YTC ATN+ G    S  L V
Sbjct: 5666 GTDSGTYTCSATNKAGHNQCSGHLTV 5691



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 52/240 (21%), Positives = 95/240 (39%), Gaps = 16/240 (6%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            VD++E      E   +  G   + ++W  +GK I  S      +   +    I      D
Sbjct: 6077 VDVTEKDPMTLEC--VVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQD 6134

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            SG Y+ +  N +G +     L  +D++    P FT  +  ++ +  G S H EC V    
Sbjct: 6135 SGQYTFKVENDFGSSSCDAYLRVLDQN--IPPSFTKKLTKMDKVL-GSSIHMECKV--SG 6189

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
               +  +W+ +G+ +  S + + V     V L++   +  D+  Y C+  N  G+D    
Sbjct: 6190 SLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDD---- 6245

Query: 3238 TINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEG 3297
               C    G+      P  L K    +++  +  +  +     PP  I   +D  +LV G
Sbjct: 6246 --AC---SGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSG 6300



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F   +   TV E E V+  C V+  E   +RI+W + G+ +    R    +  G   
Sbjct: 9272 PPVFDQHLTPVTVSEGEYVQLSCHVQGSEP--IRIQWLKAGREIKPSDRCSFSFASGTAV 9329

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            L++  V   DSG+Y+C+A N  G D TK+ ++ K  P +
Sbjct: 9330 LELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV 9368



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 13/141 (9%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFF 962
            +TQ P F  P++  + + EG  A FEA +   G     V W +DG+ +  S+   +   F
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            + G   LTI +VT  ++G Y+ +A N  GQAT++A L +       AE+  P  ++++Q 
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK------AETAPPNFVQRLQS 112

Query: 1023 LEDASRYSKRTEEEVKITQKP 1043
            +    R   +   +V++T  P
Sbjct: 113  M--TVRQGSQVRLQVRVTGIP 131



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 52/201 (25%), Positives = 76/201 (37%), Gaps = 13/201 (6%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G   M + WF +GK I AS R R  +  G   LEI+     D+G ++CRATN  G  + S
Sbjct: 5065 GSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSS 5124

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD-DPDMKIEWYHNGQPMRH 3194
              L        + P F T      G KD       C          + I W+   + +  
Sbjct: 5125 GAL-----IVQEPPSFVTK----PGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVS 5175

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK-GGVYLESLQ 3253
                    +     L++   +  DSG Y C+  N  G      + N + K    ++E L+
Sbjct: 5176 GGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG--VECSANLFVKEPATFVEKLE 5233

Query: 3254 PDSLAKIRELESLQGAQQQTP 3274
            P  L K  +   L      TP
Sbjct: 5234 PSQLLKKGDATQLACKVTGTP 5254



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 37/114 (32%), Positives = 54/114 (47%), Gaps = 3/114 (2%)

Query: 631  DRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR 690
            DR+ PP  FI  LK V A+ G  +  E R+   G   + + W ++G  I +  +  S F 
Sbjct: 7663 DRIVPP-SFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFS 7719

Query: 691  FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
                +L++  L   D+G YTC A +  G  E  AVL V    + E+T    E L
Sbjct: 7720 ENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVL 7773



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 3/115 (2%)

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
            Q  ST   + + + +PP FV  L+  T V +G     + +V  +  P   ++FY +G  +
Sbjct: 88   QATSTAELLVKAETAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEI 144

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
            QS+  F I+ +    SL I    PED+G YSV A N++G  TS   + V  +  +
Sbjct: 145  QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 2/92 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F R L ++  + G +V LECR+   G   + V WF +G  I +G + + ++  +   L
Sbjct: 7668 PSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 7725

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L  + P D+G+YTC A N  G    S  L V
Sbjct: 7726 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 7757



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 71/322 (22%), Positives = 126/322 (39%), Gaps = 34/322 (10%)

Query: 1531 SCRLTCRSTTDIV---RSTQNEAGLEQIQVLEDR-SKYHRTDMVDEVTTQAPICTTSLKN 1586
            +C +T ++ T ++   ++  N+AGL   +V  D  S    + +V +   + P+    L  
Sbjct: 9222 NCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP 9281

Query: 1587 VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPED 1646
            V + EG+       +       ++++W    + +K   R + +   G   L++      D
Sbjct: 9282 VTVSEGEYVQLSCHV--QGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKAD 9339

Query: 1647 SGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV 1706
            SG Y C+A N  G   T     +  K ++   ++      RL                  
Sbjct: 9340 SGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRL------------------ 9381

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
                  F    + IRV E   A F A++   GDP   V+W +             +H  G
Sbjct: 9382 -----FFVSEPQSIRVVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLNQGGRVFIHQKG 9434

Query: 1767 YVA-LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-QSKASLQLESQHESALQKIQQL 1824
              A L ++     DSG Y C A NE GE  ++  L V + K   ++E    + L+K   L
Sbjct: 9435 DEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPIL 9494

Query: 1825 EDSSRYQRREDV-EVAVNQAPR 1845
            +  +  +   D+ E+  N  P+
Sbjct: 9495 KKGAGEEEEIDIMELLKNVDPK 9516



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 68/300 (22%), Positives = 122/300 (40%), Gaps = 40/300 (13%)

Query: 4442  IKWYR--ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLV 4499
             +KW +  E  P  N   +++  +  K +L I+     D   +   A    G  K  A L+
Sbjct: 13691 LKWTKNGEEVPFDNRVSYRVDKY--KHMLTIKDCGFPDEGEYIVTA----GQDKSVAELL 13744

Query: 4500  VEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIR 4559
             + E          P  F    ++  VT         +++  K  +V W +NG++++   +
Sbjct: 13745 IIE---------APTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKK 13794

Query: 4560  NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
              K  E+DG+   LI++                  + R D EC  +      K + +    
Sbjct: 13795 YKF-EKDGSIHRLIIK------------------DCRLDDECEYACGVEDRKSRARLFVE 13835

Query: 4620  NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
               P EII P +D + A G  + F  ++  K    VQW + + ++      QM      + 
Sbjct: 13836 EIPVEIIRPPQDILEAPGADVVFLAEL-NKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHR 13894

Query: 4680  LRISEAFPEDEGDYKCVAYNSAGR--VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
             L+I +  P D+G+Y+ +A +   R  + +AA  K+   DQ   +    PL  +V Y+  P
Sbjct: 13895 LQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYP 13954



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 2/96 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F+  L+ + A  G  +  + ++   G P + + W K    +  +  + + F     +
Sbjct: 7005 PPYFVTELEPLEAAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTNNVAT 7062

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L    +NI DSGEYTC+A ++ G A +K V  +  R
Sbjct: 7063 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 7098



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 31/108 (28%), Positives = 55/108 (50%), Gaps = 3/108 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   ++    +K+  F  +E ++   G   ++V W KD   ++ SS+    F    
Sbjct: 8230 EPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDSV 8287

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014
              L + +++V D+G YTC A+NA G A++S +L  V +  I  +  HP
Sbjct: 8288 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLK-VKEPPIFRKKPHP 8334



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 2/106 (1%)

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            + PP+     +NV V  G+ V L+  ++G     V W +   +++  I  +I  + G   
Sbjct: 940  VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 999

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
            L+I EA+ +DSG++ C A+N AG       C +++  +++  K  T
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTV--STSCYLAVQVSEEFEKETT 1043



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 105/508 (20%), Positives = 194/508 (38%), Gaps = 58/508 (11%)

Query: 4306 GDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQ 4365
            G+ +TS  +  +     +   DQT   +++ V +     P      E    GK + +   
Sbjct: 2607 GENITSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANP--DSKGEWLRDGKHLPLTNN 2664

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
             +++ +    + I       +  E  +K  T +   +  V+  K     K ++   V E 
Sbjct: 2665 IRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVK---IKKTLKNLTVTET 2721

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            + A F VE     +  ++W +    ++++  + I    T   L I+   + D +V+    
Sbjct: 2722 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGF-- 2779

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
              R G    SA L VE  +      I  P      +N  V     V  DT       + V
Sbjct: 2780 --RLGRLGASARLHVETVKI-----IKKPKDVTALENATVAFEVSVSHDT-------VPV 2825

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W     +++P  +++++ E   + L++    P D+G+Y  V     G+  C A+  V  
Sbjct: 2826 KWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVE- 2880

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                               I + +K+  V E +   F C++    +P++ W K    I+ 
Sbjct: 2881 ----------------TLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEM 2923

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+ F++      + L I     ED  +Y  V     G   V+A L VT       +   +
Sbjct: 2924 SEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGNDQVSATLTVTP------IMITS 2973

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             L+DI   E     F+  +  +   + +WL+ G  I  T   QM  +     L I N + 
Sbjct: 2974 MLKDINAEEKDTITFEVTVNYE-GISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHF 3032

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             D   +    T  AG+  ++A L V+++
Sbjct: 3033 GDAADY----TFVAGKATSTATLYVEAR 3056



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 2/107 (1%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V V + P F+ +++    +  G+SA   C+++    P ++V W+ N K L   +  R   
Sbjct: 4658 VTVREPPSFVKKVDPSYLMLPGESARLHCKLKG--SPVIQVTWFKNNKELSESNTVRMYF 4715

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
                A LDI  V  EDSG Y+C+A+N++G    S  + ++   S I+
Sbjct: 4716 VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIK 4762



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 2/98 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP FT P++++    N     + ++   G   +RV W ++G  I AS+R       G  +
Sbjct: 5039 APFFTKPLRNVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            L +  V+  D+G +TCRA N +G   +S  L VQ   S
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPS 5134



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 82/385 (21%), Positives = 153/385 (39%), Gaps = 28/385 (7%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            ++P FT     IE L+E +     A +  T  P  ++ W+ +   L++G +++TF     
Sbjct: 5318 ESPYFTKEFKPIEVLKEYD-VMLLAEVAGT--PPFEITWFKDNTILRSGRKYKTFIQDHL 5374

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGME-GTIDKIA 3536
            V L+I      D+GEY CR  N  G ++ +A + ++   + I + +    +  GT    A
Sbjct: 5375 VSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQA 5434

Query: 3537 ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
             L+G      T   +++     E T   +  +  EN+ A      I V      V    N
Sbjct: 5435 TLKGSLPITVTWLKDSD-----EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKN 5489

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGG--VYQRDAGLYTCKATN---------RHG-EATVS 3644
               +   S + ++ +   +  E     V Q D      K +          + G E T+ 
Sbjct: 5490 DAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLG 5549

Query: 3645 CKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHK---REEITIEDEKPNPPRFTVEI 3701
             K ++     + +   + +  K   E   +++  + +   +  I + D    P  FT ++
Sbjct: 5550 SKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPP-SFTKKL 5608

Query: 3702 KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIY 3761
            K  +D  +G  +  +C V   G   + I WF + +  +   +           L+I  + 
Sbjct: 5609 K-KMDSIKGSFIDLECIV--AGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLE 5665

Query: 3762 ARDAGEYTCRATNKWGSATTTAKIT 3786
              D+G YTC ATNK G    +  +T
Sbjct: 5666 GTDSGTYTCSATNKAGHNQCSGHLT 5690



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIF 823
           T+Q P F +PLQ +  L EG  A FEA ++    P   V W++DG+ I+ S+   +   F
Sbjct: 2   TTQAPTFTQPLQSVVVL-EGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           + G   L I  +   ++G Y+++A N  G+A STA + V A +
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 58/289 (20%), Positives = 110/289 (38%), Gaps = 7/289 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +   +     G     +  +RG+    V+W + +  + E  K  M ++   G   
Sbjct: 4850 PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSN--GVAV 4907

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L+I  +     G+YTC A N+ G       +  +                    T+E+  
Sbjct: 4908 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTV 4967

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             GT     +  +  + +  +     S  ++     F    L +           VG S  
Sbjct: 4968 AGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSC 5027

Query: 251  QIS-TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
            + + T +DR + P     +    RN         +   +++G+   RV+WFK+G+ +  S
Sbjct: 5028 ETTFTVLDRDIAPFFTKPL----RNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAAS 5083

Query: 310  NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            +++ I       +L +     +D+G++T  A N  G   +SG L V+ P
Sbjct: 5084 DRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEP 5132



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 2/111 (1%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            PQFI+    +  L+ G++  FE Q+T    P +RV WY DG  ITA  +    F  G  +
Sbjct: 5788 PQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 5845

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRY 880
              I   R E++G+Y   A N  G A  +  ++V    T   +L   E  +Y
Sbjct: 5846 FQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKY 5896



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 51/219 (23%), Positives = 86/219 (39%), Gaps = 6/219 (2%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            +P KPP+F + + P  V E E  +      G     I+W +    IK S        S  
Sbjct: 9268 EPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGT 9327

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG----RGGIVPPSFTLTA- 4520
            ++L +R V   DS  +   A N  G+    + + +++K        +  +    F ++  
Sbjct: 9328 AVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEP 9387

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG-KKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            Q++ V          KV G    +V W K   +++    R  I ++     L I +    
Sbjct: 9388 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKT 9447

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKA 4618
            DSG Y CVA N  GE   +    V     ++K +   +A
Sbjct: 9448 DSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRA 9486



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F  P+++  S+  G     + ++   G   +RV W KDG+ + AS R    F  G  +
Sbjct: 5040 PFFTKPLRNVDSVVNGT-CRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I  V ++DAG++TCRA N++G   +S  L +
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 5129



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 45/193 (23%), Positives = 81/193 (41%), Gaps = 8/193 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    +  V +S G  A  +  L   G   + + W+     +  +   +  +   + 
Sbjct: 8887 PPYFVKQLEP-VKVSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVA 8943

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L        DSG Y C+A N  G+   S  L  V + K   P F+  +++++    G  
Sbjct: 8944 TLVFNQVDINDSGEYICKAENSVGEVSASTFL-TVQEQK-LPPSFSRQLRDVQETV-GLP 9000

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              F+C  +   +P + + WY +G+P++ S  ++T        L+I  T    +G+Y C A
Sbjct: 9001 VVFDC-AISGSEP-ISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTA 9058

Query: 3227 YNKYGEDFTRATI 3239
             N  G   + A +
Sbjct: 9059 TNPIGSASSSARL 9071



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 3/94 (3%)

Query: 4622  PPEI-IEP-LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             PP I ++P  KD IV   G++ +    I GKP+PT+QW KGD+ +  +   ++  T    
Sbjct: 23467 PPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT 23526

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +L + +A   D G+Y   A N AG  +V   +KV
Sbjct: 23527 SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 23560



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)

Query: 3268 GAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPH 3327
            G+   + +    EPP F+ ++     ++ G+SA    +L     P ++V WF N K+L  
Sbjct: 4650 GSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSE 4707

Query: 3328 GHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +  R +      ILDI     E+SG Y C A N +G DS    +
Sbjct: 4708 SNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 4752



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 48/192 (25%), Positives = 83/192 (43%), Gaps = 11/192 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F     D++ +  GQ    +A++   G + + + W    + I    +I+  ++ G+ 
Sbjct: 4850 PPTFVKKVDDLIALG-GQTVTLQAAV--RGSEPISVTWMKGQEVIREDGKIKMSFSNGVA 4906

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            VL I   + +  G Y+C A N+ G ++ SV  E + K   +       IQ    +  G  
Sbjct: 4907 VLIIPDVQISFGGKYTCLAENEAG-SQTSVG-ELIVKEPAKIIERAELIQ----VTAGDP 4960

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A  E TV     P++K +WY +G+P+  S + +         L     + HDSG+Y    
Sbjct: 4961 ATLEYTVAGT--PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEI 5018

Query: 3227 YNKYGEDFTRAT 3238
             N+ G      T
Sbjct: 5019 SNEVGSSSCETT 5030



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 35/104 (33%), Positives = 48/104 (46%), Gaps = 3/104 (2%)

Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG 1500
            T+ P F TR     N + G  V  ECK+       + V WF  G  ++ G +++      
Sbjct: 8606 TVPPSF-TRKLKETNGLSGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDN 8662

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVR 1544
              AL +  L   DSG YTC A N+ G+DE S  LT R     V+
Sbjct: 8663 TCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQ 8706



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 3/107 (2%)

Query: 468   RNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRITW-- 524
             +N+ GE+ +     V+ KE +  P    + S  L V+ G+ + L A   G P P + W  
Sbjct: 19105 KNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTK 19164

Query: 525   QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              KD   +  +P ++I T   +S   + +AK SD   Y  TA N AGS
Sbjct: 19165 DKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGS 19211



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 4722 PALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMIHEGNNAVL 4778
            P  T PL+ +VV EG  A F+  I+    P + W R+G +I  +  P  Q+      A L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             I    + ++G ++ +AT  +GQ  ++A+L+VK++T
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 2/92 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F++ L  ++ V G+++H+EC++   G   +  +WF +GK I T  ++R       V+L
Sbjct: 6164 PSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSL 6221

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            ++ ++  ED+  YTC+ +N  G+   S  L V
Sbjct: 6222 EVNNLELEDTANYTCKVSNVAGDDACSGILTV 6253



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 3/103 (2%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V+  + P F+T+L  P + + G S   +C++   P+  + V WY     L+    YRT  
Sbjct: 7000 VSTLEPPYFVTELE-PLEAAVGDSVSLQCQVAGTPE--ITVSWYKGDTKLRPTPEYRTYF 7056

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
                A L    V   DSGEYTCKA N++G A S     +Q ++
Sbjct: 7057 TNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ 7099



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 34/98 (34%), Positives = 45/98 (45%), Gaps = 2/98 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F K     E  +G  VHLE  L     P   V WY + R ++ G ++K   +  
Sbjct: 8322 VKEPPIFRKKPHPIETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENF 8379

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
              ++ IL   A D G Y CKATN VG      S+ + A
Sbjct: 8380 LTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA 8417



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 55/256 (21%), Positives = 104/256 (40%), Gaps = 24/256 (9%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYN-GKTIEASHRIRTVYAFGM 3105
            PP F     DI  +  G+    + ++   G + + + WF + G+ +  S  I   Y+  +
Sbjct: 8418 PPRFVKKLSDISTVV-GKEVQLQTTI--EGAEPISVVWFKDKGEIVRESDNIWISYSENI 8474

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK--D 3163
              L+    +  ++G Y+C+  N  G  E    L  ++ +        T ++  E +K   
Sbjct: 8475 ATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPA--------TIVEKPESIKVTT 8526

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV-LDIAYTQNHDSGEY 3222
            G +   ECTV     P++  +W+ +G+ +    + K +S F  V  L I      DSG Y
Sbjct: 8527 GDTCTLECTV--AGTPELSTKWFKDGKELTSDNKYK-ISFFNKVSGLKIINVAPSDSGVY 8583

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282
                 N  G+D   A++       V   ++ P    K++E   L G+           PP
Sbjct: 8584 SFEVQNPVGKDSCTASLQ------VSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPP 8637

Query: 3283 KFITQIQDVTKLVEGQ 3298
              ++   +  ++  G+
Sbjct: 8638 ISVSWFHEGNEISSGR 8653



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 54/229 (23%), Positives = 89/229 (38%), Gaps = 15/229 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP FT   K+   +S   +   E  +   G   + + WF+ G  I +  + +T       
Sbjct: 8608 PPSFTRKLKETNGLSGSSVV-MECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTC 8664

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L +   + +DSG Y+C ATN  G  E S  L     +  + P F      ++ L  G +
Sbjct: 8665 ALTVNMLEESDSGDYTCIATNMAGSDECSAPL-----TVREPPSFVQKPDPMDVL-TGTN 8718

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              F  T +    P   + W+     +    R     +     L++       SGEY C  
Sbjct: 8719 VTF--TSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIV 8776

Query: 3227 YNKYGEDFTRATINCYGKG-GVYLESLQPDSLAKIRELESLQGAQQQTP 3274
             N+ G+     T + Y K    +++ L   S+ K + L  L+G    TP
Sbjct: 8777 SNEAGK--ASCTTHLYIKAPAKFVKRLNDYSIEKGKPL-ILEGTFTGTP 8822



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 11/171 (6%)

Query: 393   QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
             +F++   D  V E +M RF+C ++ R   +V WF +  +I+    + I +++     L+I
Sbjct: 13302 EFLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDI-ISKGAVRILVI 13359

Query: 453   TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
                 L D    +C  R  +  T+    L V+E+E V    F +  + + V E + + L  
Sbjct: 13360 NKCLLDDEAEYSCEVR--TARTSGM--LTVLEEEAV----FTKNLANIEVSETDTIKLVC 13411

Query: 513   RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
               V  P   + W K    II      I T+G    L I  A   DA  Y C
Sbjct: 13412 E-VSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 13461



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 1/105 (0%)

Query: 467   ARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
             A+N+ G     Q  + VI K+ V+ P F   F+T  V  GE + ++   +G PTP +TW 
Sbjct: 23050 AQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH 23109

Query: 526   KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             KD VP+     +   +    S L I  A   D   Y     N AG
Sbjct: 23110 KDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 23154



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 5/125 (4%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            +I  K    + TE E         + GP     PP F K+++P R  +   A FE    G
Sbjct: 3591 KINSKGEGHKDTETESAVAKSLEKLGGPC----PPHFLKELKPIRCAQGLPAIFEYTVVG 3646

Query: 4437 EPLPLIKWYRENFPIKNSPDFQ-IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            EP P + W++EN  +  S  +  IH  +     I+     EDS ++   AEN  G + C+
Sbjct: 3647 EPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCA 3706

Query: 4496 ANLVV 4500
            A L+V
Sbjct: 3707 AELLV 3711



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            + P F T L+  +  V G  V L+ QV     P + + W+K    L      ++ F   +
Sbjct: 7004 EPPYFVTELEPLEAAV-GDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYFTNNV 7060

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             TL  N +  +DSG YTCKA N +G A S    +I++R
Sbjct: 7061 ATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 7098



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 71/287 (24%), Positives = 117/287 (40%), Gaps = 35/287 (12%)

Query: 3370 ANLKCTSKENLILDSQLPRGM-EGGLEKLQTLEDSMVRRKDTSVE-EEKGKAPVFTVPLS 3427
            +N + T K N ++      GM + GL   +   D+      +S+  +E  K PVF   L+
Sbjct: 9221 SNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 9280

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
             +  + EGE       +  ++   ++++W   G+ +K   R       G  +LE+     
Sbjct: 9281 PV-TVSEGEYVQLSCHVQGSEP--IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAK 9337

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             DSG+Y+C+A N  G   T + + ++ K         P     T  K AA++G    V  
Sbjct: 9338 ADSGDYVCKASNVAGSDTTKSKVTIKDK---------PAVAPAT--KKAAVDGRLFFV-- 9384

Query: 3548 LTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH-NGKPLLTGSRV 3606
                          + P  + + E ++A F  ++    D    V+W     + L  G RV
Sbjct: 9385 --------------SEPQSIRVVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLNQGGRV 9428

Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
                      LEI    + D+GLY C A N HGE   +  LQV  R+
Sbjct: 9429 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERK 9475



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 51/207 (24%), Positives = 79/207 (38%), Gaps = 12/207 (5%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            I I E    P F +      V+EG+  +  C V G     + W    R+I+         
Sbjct: 9264 IVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSF 9323

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV-APK--------- 492
              SG   L + +V  +DSG   C A N +G    + ++ + +K  V  A K         
Sbjct: 9324 -ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLF 9382

Query: 493  FVERFSTLNVREGEPVVLNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIP 551
            FV    ++ V E       A+  G P P + W K     +     + IH  G  + L+I 
Sbjct: 9383 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIR 9442

Query: 552  RAKASDAAWYQCTAQNVAGSTATRARL 578
                +D+  Y+C A N  G   +   L
Sbjct: 9443 DTTKTDSGLYRCVAFNEHGEIESNVNL 9469



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 56/227 (24%), Positives = 95/227 (41%), Gaps = 27/227 (11%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            ++ P+F  HL     + EG++V L   V+  ++P ++I+W K G  +    R   +F  G
Sbjct: 9270 KKPPVFDQHLTPVT-VSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASG 9326

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXX 2758
               L +  +   DSG Y CKA+N+ G   + + + I+D+   +  +    ++D  G L  
Sbjct: 9327 TAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKP-AVAPATKKAAVD--GRL-- 9381

Query: 2759 XXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN-KPLP 2817
                             F+S   +I   E     F   V    DP   ++W     + L 
Sbjct: 9382 ----------------FFVSEPQSIRVVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLN 9423

Query: 2818 SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
             G R           L+I  T + DSG+Y C A N  G   ++ +L+
Sbjct: 9424 QGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQ 9470



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 54/186 (29%), Positives = 86/186 (46%), Gaps = 14/186 (7%)

Query: 388   KALAPQFVKVCQDRDVTE----GKMTRFDCRVTGRPYPEVT-WFINDRQIRDDYNHKILV 442
             KA+  +FVK  +D  +TE    G    F+C V+  P   +T W  +   IR+   H+ + 
Sbjct: 12038 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIA 12095

Query: 443   NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +  +  L I +V LSD+G  TCV R  + E     +L V+E+  V   K +E    + V
Sbjct: 12096 -DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKL-VVEELPVRFVKTLE--EEVTV 12151

Query: 503   REGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWY 561
              +G+P+ L+          + W+KDG  ++  P  +     G    L I  A  +DA  Y
Sbjct: 12152 VKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTY 12209

Query: 562   QCTAQN 567
               T +N
Sbjct: 12210 TVTVEN 12215



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++  V +G  V L+  +T +  PT  V++Y +G  +Q    F+ + +    +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             I  AY ED+GTY   ATN+VG A +T+ + V  +
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 4/111 (3%)

Query: 1439 SVTIK--PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            +VT++  P FV +      ++ G+     CKL+      ++V WFKN + ++  +  R  
Sbjct: 4657 TVTVREPPSFVKKVDPSYLMLPGESARLHCKLKG--SPVIQVTWFKNNKELSESNTVRMY 4714

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
                   LDI D+  EDSG Y+C AVN VG+D  S  +  +     +++ +
Sbjct: 4715 FVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLE 4765



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 30/83 (36%), Positives = 45/83 (54%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+PL+N+D++  G T   DC++   G   ++V WF++ K I  S R       G  S
Sbjct: 5040 PFFTKPLRNVDSVVNG-TCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V   D G + CRA+N +G
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVG 5119



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 38/122 (31%), Positives = 63/122 (51%), Gaps = 8/122 (6%)

Query: 3268 GAQQQTPSTPSAEPPKFITQIQDVTKLVE-GQSAHFEARLVPVDDPDLKVEWFYNGKKLP 3326
            G+   T      EPPKF+ +++  +K+V+ G S+  E ++     P+++V WF N  +LP
Sbjct: 6336 GSDSCTTMLLVTEPPKFVKKLE-ASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELP 6392

Query: 3327 HGHRYR-TFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQ 3385
               +YR TF D  + ++ +     E+SG++ C A N  G  ST  + K   KE  +  S 
Sbjct: 6393 ASDKYRMTFID-SVAVIQMNNLSTEDSGDFICEAQNPAG--STSCSTKVIVKEPPVFSSF 6449

Query: 3386 LP 3387
             P
Sbjct: 6450 PP 6451



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 27/87 (31%), Positives = 47/87 (54%), Gaps = 3/87 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P+F +   +P    +G ++HLEC L+  G P   V W+ + R +  G ++K   +  
Sbjct: 8323 KEPPIF-RKKPHPIETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENF 8379

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGS 1260
              ++ I++  +AD GEY  +A N +GS
Sbjct: 8380 LTSIHILNVDAADIGEYQCKATNDVGS 8406



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 3/101 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F  +L     LS G S   EC++  Y  P + V W+  G  + SG +Y+T+      A
Sbjct: 8609 PSFTRKLKETNGLS-GSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 8665

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            L +  +   DSG+YTC A N  G    S  L V+   S ++
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQ 8706



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 4/119 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F      P     G+SA +EC +     P ++V W  + + ++SG +Y+ S     A 
Sbjct: 9079 PPFFDIRLAPVDAVVGESADFECHVTG-TQP-IKVSWAKDSREIRSGGKYQISYLENSAH 9136

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
            L +L V   DSG+YTC A+N +G+   + +LN+  KE +I  S  +   E ++  E +S
Sbjct: 9137 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI--KERLIPPSFTKRLSETVEETEGNS 9193



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765
            TQAP FT P++ + V E   A FEA +   G P   V W R+G  I  S        F  
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSD 60

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            G   L +  V   +SG Y+ +A N  G+A +++ L V+++ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 3/93 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F +PL+++  +  G     + ++   S P MRV W+KDG+ I AS R    F  G  S
Sbjct: 5040 PFFTKPLRNVDSVVNG-TCRLDCKIAG-SLP-MRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            L I+ +   DAG++T RA N +G   S+ ++ V
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 5129



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 3/91 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P FT  ++ N+D    G    DC++   G   MR+ WF +G+  A   R       G  +
Sbjct: 5040 PFFTKPLR-NVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L+I  +   DAG +TCRATN  GS  ++  +
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGAL 5127



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 3/147 (2%)

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV-EESEGVRFECRVEPKEDPKLR 3862
            SG  I +L     +   K    V  PP+FI +     V    +   FEC++     PK+R
Sbjct: 5762 SGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGT--PKIR 5819

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            + WY +G  + +  ++   +  G  +  I     E+SG Y+C A ND G       +  K
Sbjct: 5820 VSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 5879

Query: 3923 KLPDIILQNQVPRGMKRSEALTQMEAT 3949
            + P  I + +    +K S+   + E T
Sbjct: 5880 EPPTFIRELKPVEVVKYSDVELECEVT 5906



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  LK  + L  G  V +E +V     P + + WF  G  +++G + ++T       
Sbjct: 8609 PSFTRKLKETNGL-SGSSVVMECKVYG--SPPISVSWFHEGNEISSGRKYQTTLTDNTCA 8665

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L++N L   DSG YTC ATN+ G    +A + + +
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE 8700



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 83/397 (20%), Positives = 142/397 (35%), Gaps = 24/397 (6%)

Query: 3265 SLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKK 3324
            ++ G+ + +      EPP F+ Q  D   ++ G +  F +  +    P   V WF    +
Sbjct: 8685 NMAGSDECSAPLTVREPPSFV-QKPDPMDVLTGTNVTFTS--IVKGTPPFSVSWFKGSSE 8741

Query: 3325 LPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDS 3384
            L  G R     +  +  L++       SGEY C+ +N+ G+ S   +L   +    +   
Sbjct: 8742 LVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRL 8801

Query: 3385 QLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARL 3444
                 +E G  K   LE +       SV  +K    V      NI      ++A  E   
Sbjct: 8802 N-DYSIEKG--KPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTE--KSAILEIPS 8856

Query: 3445 TPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPE--DSGEYLCRA----- 3497
            +  +D      +  N     + S      +  + + ++ P      DS    C+      
Sbjct: 8857 STVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPE 8916

Query: 3498 -----YNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTV--DTLTP 3550
                 Y    +   T + K+  + N+         +  + + I   E   G V   T   
Sbjct: 8917 IGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLT 8976

Query: 3551 EAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN 3610
              E   PP F+    D+  +      F+C +       + V W+ +GKPL     V+T  
Sbjct: 8977 VQEQKLPPSFSRQLRDVQETVGLPVVFDCAI--SGSEPISVSWYKDGKPLKDSPNVQTSF 9034

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
                  L I    +  AG Y+C ATN  G A+ S +L
Sbjct: 9035 LDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 3/117 (2%)

Query: 1160 SKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS 1219
            +KF   + Q E I   KP F++ L  P   +  K +HLEC+++   D  + V W  +G+ 
Sbjct: 4554 NKFGADICQAELIIIDKPHFIKELE-PVQSAINKKVHLECQVDE--DRKVTVTWSKDGQK 4610

Query: 1220 VTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276
            +  G  +K  ++     L+I  A   D+G Y   A N  GS+  SA V V E    V
Sbjct: 4611 LPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFV 4667



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F+  LK  N I+ G S   E RV   + ++  V W+ +G +I S  + Q+        
Sbjct: 7668 PSFIRKLKDVNAIL-GASVVLECRVSGSAPIS--VGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
            L+++ +   D+G+YT VA N AG  + SA +TV+   S +
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFE 7764



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 3/104 (2%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ + + P F+ QL  P K+S G SA  +C++   P+  + V WY     L+    Y+  
Sbjct: 8881 QILILEPPYFVKQLE-PVKVSVGDSASLQCQLAGTPE--IGVSWYKGDTKLRPTTTYKMH 8937

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
                 A L    V   DSGEY CKA N++G+  +S  L VQ ++
Sbjct: 8938 FRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK 8981



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 54/232 (23%), Positives = 92/232 (39%), Gaps = 31/232 (13%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            PVF   +  + V+E +       +   G   +R++WL+ G  I+ S+R +     G   L
Sbjct: 9273 PVFDQHLTPVTVSEGEYVQLSCHV--QGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVL 9330

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             ++ V   DSG Y C+A N  G   T S + ++ K ++   ++  +   ++  + +    
Sbjct: 9331 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEP--- 9387

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK--VLQ 1888
               + + V       FI ++ G                    DP   V+W   GK   L 
Sbjct: 9388 ---QSIRVVEKTTATFIAKVGG--------------------DPIPNVKW-TKGKWRQLN 9423

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             G R         A L+I      DSG Y C A N  G+  S++ L V  ++
Sbjct: 9424 QGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERK 9475



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 45/187 (24%), Positives = 91/187 (48%), Gaps = 15/187 (8%)

Query: 4624  EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
             E+++P++D  + E ++  F  +I    +P  QW    +L++PS   ++     +  L + 
Sbjct: 12325 ELLKPIEDVTIYEKESASFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLR 12383

Query: 4684  EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
             +   +  G+   V Y +   +T A  L V + +    L    PL+D+ V E + A+F+  
Sbjct: 12384 KVKLDQAGE---VLYQALNAITTAI-LTVKEIE----LDFAVPLKDVTVPERRQARFECV 12435

Query: 4744  ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
             +T +    + W +   +I  +  F +I +G   +L+I ++  +D G +T       G+ +
Sbjct: 12436 LTREAN--VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAE---VEGK-K 12489

Query: 4804  TSAKLVV 4810
             TSA+L V
Sbjct: 12490 TSARLFV 12496



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 52/230 (22%), Positives = 93/230 (40%), Gaps = 15/230 (6%)

Query: 347   IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
             I+T G   +     ++++D    Y        T+ ++++ E  LA +F+   Q+ ++ EG
Sbjct: 13437 ILTEGRKRILVIQNAHLEDA-GNYNCRLPSSRTDGKVKVHE--LAAEFISKPQNLEILEG 13493

Query: 407   KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
             +   F C ++   +P V W  +D+ +     + ++  +     L++ + TL D G    +
Sbjct: 13494 EKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIA-DGKKRVLVVKDATLQDMGTYVVM 13551

Query: 467   ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
                  G       L VIEK ++V P          V+E + VV N   V T   +  W +
Sbjct: 13552 V----GAARAAAHLTVIEKLRIVVP-----LKDTRVKEQQEVVFNCE-VNTEGAKAKWFR 13601

Query: 527   DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
             +   I  + +  I       TL I  A   D A Y  +  N  G     A
Sbjct: 13602 NEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSA 13651



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 1/93 (1%)

Query: 482   VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             VI K+  + P     F+T +++ GE + +    +G P P I+W KDG P+     + +  
Sbjct: 25230 VIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEE 25289

Query: 542   DGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
                ++ L I      D   Y  TA N AG TAT
Sbjct: 25290 TATSTVLHIKEGNKDDFGKYTVTATNSAG-TAT 25321



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 1/92 (1%)

Query: 67   GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
            G P PP F +  K  R AQG  A FE  + G P P V+W ++   L     Y++ +N   
Sbjct: 3616 GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHN-PN 3674

Query: 127  GDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            G  + ++      D G Y C A N  GE+ C+
Sbjct: 3675 GSGTFIVNDPQREDSGLYICKAENMLGESTCA 3706



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 30/103 (29%), Positives = 52/103 (50%), Gaps = 5/103 (4%)

Query: 1305 ITVMQAPQFSRALH-NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV + P F + +  +   + G +  L C+L+  G   ++V WF N K +   +  R  +
Sbjct: 4658 VTVREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYF 4715

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
                  LD+  V  EDSG Y+C+A N +G    SC+  ++ K+
Sbjct: 4716 VNSEAILDITDVKVEDSGSYSCEAVNDVGS--DSCSTEIVIKE 4756



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 2/154 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP FI ++K   V +   V  EC V     P   + W +N + + S  +Y     + 
Sbjct: 5878 VKEPPTFIRELKPVEVVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTLTDRVS 5935

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945
              +L I      D+GEY C   N+ G       ++ K+ P  I + +    + +S A  Q
Sbjct: 5936 VFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQ 5995

Query: 3946 MEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQI 3979
                     S  +L +D + D D      FV  +
Sbjct: 5996 STVAGSPPISITWLKDDQILDEDDNVYISFVDSV 6029



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 28/100 (28%), Positives = 56/100 (56%), Gaps = 2/100 (2%)

Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            GVQ+ P F   L+   ++V+ Q  +   + +    P +K+ W+K+   +   ++ + +F 
Sbjct: 8227 GVQEPPRFIKKLEP-SRIVK-QDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFV 8284

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              +  L +++L  +DSG YTC+A N  G A S+ S+K+++
Sbjct: 8285 DSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE 8324



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 27/101 (26%), Positives = 54/101 (53%), Gaps = 3/101 (2%)

Query: 3826 VSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP+FI +++ S  V++ E  R+EC++     P++++ WY++   +    ++R  +  
Sbjct: 8228 VQEPPRFIKKLEPSRIVKQDEFTRYECKIGGS--PEIKVLWYKDETEIQESSKFRMSFVD 8285

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L++  +  EDSG+Y C A N  G   +  ++  K+ P
Sbjct: 8286 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 8326



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 5/111 (4%)

Query: 1292 EDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK 1351
            +D+   + QV  D TV   P F+R L     + G++V +EC++   G   + V WF  G 
Sbjct: 8593 KDSCTASLQV-SDRTV--PPSFTRKLKETNGLSGSSVVMECKVY--GSPPISVSWFHEGN 8647

Query: 1352 PIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             I +G +++     +  AL +  +   DSG YTC ATN  G    S  L V
Sbjct: 8648 EISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 8698



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 31/101 (30%), Positives = 55/101 (54%), Gaps = 4/101 (3%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            +T++++K  PP F+ +++D +    G PV FDC +   G   + + W+ +G+P      V
Sbjct: 8975 LTVQEQKL-PPSFSRQLRD-VQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNV 9030

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             T        L+I       AG+Y+C ATN  GSA+++A++
Sbjct: 9031 QTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 54/213 (25%), Positives = 85/213 (39%), Gaps = 39/213 (18%)

Query: 924  GGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYT 983
            G  A FE  +   G   ++V W KD R + +  +    +      LT+  V   D+G YT
Sbjct: 9094 GESADFECHVT--GTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYT 9151

Query: 984  CRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKP 1043
            C A N +G+ + +A L I  K+ +I  S                 ++KR  E V+ T   
Sbjct: 9152 CYAVNEVGKDSCTAQLNI--KERLIPPS-----------------FTKRLSETVEET--- 9189

Query: 1044 RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVAL 1103
                         EG S   E RV     +  TV WY N  +I   +  +       + L
Sbjct: 9190 -------------EGNSFKLEGRVAGSQPI--TVAWYKNNIEIQPTSNCEITFKNNTLVL 9234

Query: 1104 DIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             +      D+G+YT    N AG A  ++S+ ++
Sbjct: 9235 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 9267



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 51/220 (23%), Positives = 93/220 (42%), Gaps = 26/220 (11%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P  +SEG+     C ++   +P +R++W   G+ ++   R   S   G A L++  V   
Sbjct: 9281 PVTVSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKA 9338

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDS 1972
            DSG+Y CKA N  G   +  ++ ++ K + +  +  ++A++   +   + +  R V+  +
Sbjct: 9339 DSGDYVCKASNVAGSDTTKSKVTIKDKPA-VAPATKKAAVDGRLFFVSEPQSIRVVEKTT 9397

Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
                    G PI N + T+G                   +W    R + QG R       
Sbjct: 9398 ATFIAKVGGDPIPNVKWTKG-------------------KW----RQLNQGGRVFIHQKG 9434

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
                L+I      D+G Y C A N  GE  +  +++VD +
Sbjct: 9435 DEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 9474



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 125/638 (19%), Positives = 243/638 (38%), Gaps = 50/638 (7%)

Query: 1174  KSKPV-FVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
             K  PV F +PL +   V EG    LEC +        +V+WF NG  +    +++   D 
Sbjct: 13208 KEPPVEFTKPLEDQT-VEEGATAVLECEVSR---ENAKVKWFKNGTEILKSKKYEIVAD- 13262

Query: 1233  GFVALDIIH-ATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ---NEQAIEQI 1288
             G V   +IH  T  D   YT  A +   S + + +   +E    +TD Q    E A  + 
Sbjct: 13263 GRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFEC 13322

Query: 1289  QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
             +L  + A+  K  ++   + +  ++         +   N   +C L          E+ C
Sbjct: 13323 ELSRENAK-VKWFKDGAEIKKGKKYDIISKGAVRILVIN---KCLLDD------EAEYSC 13372

Query: 1349  NGKPIKTGHRFRPAYEFDYVALDL--LSVYPEDSGVYTCQATNQLGEAVTSCALRVI--- 1403
               +  +T        E      +L  + V   D+    C+ +    E +       I   
Sbjct: 13373 EVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIET 13432

Query: 1404  AKKDLILESQHPSGLEKIQYLEDTSRYK------KTDIIDESVTIKPRFVTRPKSIENVI 1457
              + +++ E +    + +  +LED   Y       +TD   +   +   F+++P+++E ++
Sbjct: 13433 GRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLE-IL 13491

Query: 1458  EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
             EG+   F C    ++  +  V+W ++ + +  G ++  I D     L + D   +D G Y
Sbjct: 13492 EGEKAEFVCS---ISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 13548

Query: 1518  TCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
                 V +VG    +  LT      IV   ++    EQ +V+ +               + 
Sbjct: 13549 ----VVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEE 13604

Query: 1578  PICTTSLKNVEIKEGQRAHFERRLIPVSD-ATLKVE-WYHNNKPLKSGSR-FTETNNFGF 1634
              I  +S K + +++        R   + D A   V    H  + +KS +    E  +   
Sbjct: 13605 AIFDSS-KYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRI 13663

Query: 1635  V-ALDIMSCLPEDSGTYTCRA--INALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN-Q 1690
             V  L  +  + + S T+ C+   +N   +   +G  +    +  Y   +++  L   +  
Sbjct: 13664 VEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCG 13723

Query: 1691  LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ-AAHFEARLI--PVGDPKLRVEWL 1747
               D  +Y   + QD+ + +  +   P + +   E+Q    F+  +    +   K  V+W 
Sbjct: 13724 FPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWY 13783

Query: 1748  RNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785
             RNG  I+   +     D     L +K    +D   Y C
Sbjct: 13784 RNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC 13821



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 4/137 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH--EIITTHNHTTL 323
           P   Q  ++  + EG+ A F+  +SG P P V+WF++GQ +  S     +I  +     L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +    K++SG Y+L A N +G   ++  L V++ T      QR Q +T  Q   ++ R+
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQ--GSQVRL 123

Query: 384 EISEKALAPQFVKVCQD 400
           ++    +    VK  +D
Sbjct: 124 QVRVTGIPTPVVKFYRD 140



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 30/98 (30%), Positives = 55/98 (56%), Gaps = 2/98 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L ++   +G+ V L+ R+   G  T  V+++ +G  I++   F+ + E D  +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
             +   YPEDSG Y+  ATN +G A ++  L V  ++++
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            E + PIF +   NA  + G  A     + G P P + W      L     Y   ++    
Sbjct: 3499 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD-- 3556

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            D SL+I      DEGEYTC A N YG+ ICS Y++
Sbjct: 3557 DHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLK 3591



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 56/207 (27%), Positives = 87/207 (42%), Gaps = 24/207 (11%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI+W+FNG +L   + +K   D    +L ++     D G YTC A N  G+   S+ 
Sbjct: 3530 PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAY 3589

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            +   SK          +G +  E    +  SL K  G         PP F    K I   
Sbjct: 3590 LKINSKG---------EGHKDTETESAVAKSLEKLGGP-------CPPHFLKELKPI-RC 3632

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSG 3119
            ++G  A +E +++  G+ +  + WF   K +  S     ++   G     +   +  DSG
Sbjct: 3633 AQGLPAIFEYTVV--GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 3690

Query: 3120 TYSCRATNKWGQ----AEISVKLECVD 3142
             Y C+A N  G+    AE+ V LE  D
Sbjct: 3691 LYICKAENMLGESTCAAELLVLLEDTD 3717



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 3/101 (2%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F   L     +  G +   +C+I       MRV W+ +GK + +  RYR +   G A
Sbjct: 5039 APFFTKPLRNVDSVVNG-TCRLDCKIAG--SLPMRVSWFKDGKEIAASDRYRIAFVEGTA 5095

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            +L+I+ V   D+G +TC+A N++G   SS  L VQ   S +
Sbjct: 5096 SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFV 5136



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 29/103 (28%), Positives = 56/103 (54%), Gaps = 5/103 (4%)

Query: 1435 IIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494
            ++D++  I P F  +   ++ V+ G  +H ECK+       +  +WFK+G+ ++   ++R
Sbjct: 6157 VLDQN--IPPSFTKKLTKMDKVL-GSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYR 6211

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
             +     V+L++ +L  ED+  YTC+  N+ G D  S  LT +
Sbjct: 6212 LVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 6254



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 65/283 (22%), Positives = 112/283 (39%), Gaps = 51/283 (18%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F  ++          +  EC+V       +  +W+++GK + +  +YR V     VS
Sbjct: 6163 PPSFTKKLTKMDKVLGSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL----QNQVPRGMKRSEALT 3944
            L++  +  ED+  Y C+  N  G+D     ++ K+ P  ++    Q  +P      +A+ 
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAIL 6280

Query: 3945 Q--MEATIKKYTSEVYLTED--------------DLYDVDKKQPPRFVTQIQSQ------ 3982
            +      IK +  +V L                 +LY VD  +  ++   + +       
Sbjct: 6281 KGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSC 6340

Query: 3983 -TSLVEMETTKF-----ECQLAPVGD-----------PNMKVEWFFNGK--PLLHKNRFT 4023
             T L+  E  KF       ++   GD           P ++V WF N    P   K R T
Sbjct: 6341 TTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMT 6400

Query: 4024 PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD--ETKAVIK 4064
             I     + MN   +  EDSG+++C A N  G     TK ++K
Sbjct: 6401 FIDSVAVIQMNN--LSTEDSGDFICEAQNPAGSTSCSTKVIVK 6441



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 5/112 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            + V + P+F + L   + V+ G +  LEC++   G   +RV WF N   +    ++R  +
Sbjct: 6344 LLVTEPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTF 6401

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
                  + + ++  EDSG + C+A N  G   TSC+ +VI K+  +  S  P
Sbjct: 6402 IDSVAVIQMNNLSTEDSGDFICEAQNPAGS--TSCSTKVIVKEPPVFSSFPP 6451



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 29/99 (29%), Positives = 55/99 (55%), Gaps = 3/99 (3%)

Query: 1974 VVEKPQFGKPIKNAEVT-EGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P+F K ++ ++V  +G  + LE  ++    P ++V W+ N   + +  ++  ++  
Sbjct: 7287 VKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFIN 7344

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
                L I  A AED+G Y+C+A N VG+A  ++++ V A
Sbjct: 7345 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 7383



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 2/99 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP FI PL+ V A+ G     + +++  G P ++I W K    + ++  +   F+  
Sbjct: 7943 VLEPPYFIEPLEHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNN 8000

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
              SL +  ++  D GEY+C+A ++ G   + AVL +  R
Sbjct: 8001 VASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKER 8039



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 2/102 (1%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F  ++K         V  EC+V     P + + W+  G  + SG +Y+T      
Sbjct: 8606 TVPPSFTRKLKETNGLSGSSVVMECKVYGS--PPISVSWFHEGNEISSGRKYQTTLTDNT 8663

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
             +L +  +   DSG+Y C A N  G D   A ++ ++ P  +
Sbjct: 8664 CALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV 8705



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 41/154 (26%), Positives = 73/154 (47%), Gaps = 18/154 (11%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P + + LQ++  ++EGQT    C+      P +K EWFRN ++++   R     +     
Sbjct: 9672 PAWERHLQDV-TLKEGQTCTMTCQF---SVPNVKSEWFRNGRILKPQGRHKTEVEHKVHK 9727

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKL-EQPH 2494
            +TI+ VR ED+G Y C+  +L                 +++E +  +  K+IQ +    H
Sbjct: 9728 LTIADVRAEDQGQYTCKYEDL------------ETSAELRIEAEPIQFTKRIQNIVVSEH 9775

Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528
            +  + E +  F+  I T    GP+EL E Q  ++
Sbjct: 9776 QSATFECEVSFDDAIVTW-YKGPTELTESQKYNF 9808



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 11/179 (6%)

Query: 393   QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
             +F K  +D+ V EG     +C V+ R   +V WF N  +I     ++I V +     L+I
Sbjct: 13213 EFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEI-VADGRVRKLVI 13270

Query: 453   TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
              + T  D    TC A  K  +T+  C LNV+        +F+   + L VRE E      
Sbjct: 13271 HDCTPEDIKTYTCDA--KDFKTS--CNLNVVPPHV----EFLRPLTDLQVREKEMARFEC 13322

Query: 513   RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               +     ++ W KDG  I    +  I + G    L I +    D A Y C  +    S
Sbjct: 13323 E-LSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTS 13380



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F K  K  EV + + V L A +     P   + W+ +   ++ G ++KT     
Sbjct: 5316 VKESPYFTKEFKPIEVLKEYDVMLLAEVA--GTPPFEITWFKDNTILRSGRKYKTFIQDH 5373

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067
             V+L IL   A D G Y C+ TN VG ++ ++ V
Sbjct: 5374 LVSLQILKFVAADAGEYQCRVTNEVGSSICSARV 5407



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 23/79 (29%), Positives = 42/79 (53%)

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
            P   + W+ +  +L+SG +Y+T       +L IL     D+GEY C+  N +G ++ S R
Sbjct: 5347 PPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSAR 5406

Query: 1934 LNVQSKESIIRDSQHESAL 1952
            + ++   S I+  +  S+L
Sbjct: 5407 VTLREPPSFIKKIESTSSL 5425



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 2/125 (1%)

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            SG+ I E +    S +   + IV  PP F +        ++  V  EC  E    P   +
Sbjct: 6418 SGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLEC--ELSGTPPFEV 6475

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             WY++ + L S  +Y+        S+ IL V   D GEY C+A N+ G D    T+  K+
Sbjct: 6476 VWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE 6535

Query: 3924 LPDII 3928
             P  +
Sbjct: 6536 PPRFV 6540



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P+F      +E LK  D  H EC ++    P   + W+ + +++R+G +Y+   +    +
Sbjct: 8326 PIFRKKPHPIETLKGAD-VHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFLTS 8382

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
            + IL   A D G Y CKATN +G   +TC   +A
Sbjct: 8383 IHILNVDAADIGEYQCKATNDVGS--DTCVGSIA 8414



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P +  +G   H EC ++  P     V WY + + L+SG +Y+  ++    ++ IL V   
Sbjct: 8334 PIETLKGADVHLECELQGTPP--FHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAA 8391

Query: 1913 DSGEYTCKAINNLGQ--AVSSIRL 1934
            D GEY CKA N++G    V SI L
Sbjct: 8392 DIGEYQCKATNDVGSDTCVGSIAL 8415



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  ++++   L  G S   E ++     P + V WF+ G ++  G +Y+T       
Sbjct: 8608 PPSFTRKLKETNGL-SGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTC 8664

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             L +    E +SG+Y C+ATN  G D   A L
Sbjct: 8665 ALTVNMLEESDSGDYTCIATNMAGSDECSAPL 8696



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 4/118 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F   L  ++ V G +   EC +   G Q ++V W  + + I++G +++ +Y  +   L
Sbjct: 9080 PFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHL 9137

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
             +L V   DSG YTC A N++G+   SC  ++  K+ LI  S      E ++  E  S
Sbjct: 9138 TVLKVDKGDSGQYTCYAVNEVGK--DSCTAQLNIKERLIPPSFTKRLSETVEETEGNS 9193



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   L  VT  EG  +     ++  G   ++I+WLK G+ I+ S R +  F  G   
Sbjct: 9272 PPVFDQHLTPVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFASGTAV 9329

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            L++  +   DSG+Y C+A +  G   TK+ + +  +  +
Sbjct: 9330 LELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV 9368



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 26/66 (39%), Positives = 37/66 (56%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G+     V +SG P P+VTW     RL  +++  I TT + TTL V+++ + DSG Y L 
Sbjct: 29589 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 29648

Query: 340   AENPNG 345
              EN  G
Sbjct: 29649 LENTAG 29654



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 12/160 (7%)

Query: 1792 GEAVTSSTL------FVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQA 1843
            G+ +++STL      F   +A L + +  +  S    ++    S +     ++ V    A
Sbjct: 43   GQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102

Query: 1844 P-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            P  F+ +L   T + +G     + R+   P P   V++Y +G  +QS   ++ S +    
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +L I   Y EDSG Y+  A N++G+A S+  L VQ +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 2/99 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP FI  ++S +++ GG   F+  ++  G   + + WLK+   I         F     S
Sbjct: 5412 PPSFIKKIESTSSLRGGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTFENNVAS 5469

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            L +  + ++  G+Y C+A +  G+    A+L V   ATI
Sbjct: 5470 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATI 5508



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 56/264 (21%), Positives = 95/264 (35%), Gaps = 9/264 (3%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P   V W +    +V    +SM +       S  I+ +   D G+YT    N +G + 
Sbjct: 6093 GTPELKVKWLKDGKQIVPSRYFSMSFENNVA--SFRIQSVMKQDSGQYTFKVENDFGSSS 6150

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
            C  Y++                   V  +  H      G     S       + +G + S
Sbjct: 6151 CDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSG-----SLPISAQWFKDGKEIS 6205

Query: 217  STDDFKVDTFEYRLLREVSFRE-SITKRYVGE-SDVQISTEIDRSLGPVSPPKIAQKPRN 274
            ++  +++   E  +  EV+  E   T  Y  + S+V         L    PP    KP  
Sbjct: 6206 TSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGR 6265

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
             +    +  +F+  L G P  ++ WFK+   L++  K  I    + + L + +   S +G
Sbjct: 6266 QQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTG 6325

Query: 335  HYTLLAENPNGCIVTSGYLAVESP 358
             YT    N  G    +  L V  P
Sbjct: 6326 QYTCHVTNDVGSDSCTTMLLVTEP 6349



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 27/112 (24%), Positives = 57/112 (50%), Gaps = 3/112 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP+FV +L  +    +G++   EC++     P +++ ++ N   L  + +++++F     
Sbjct: 7290 PPKFVKKLEASKVAKQGESIQLECKISG--SPEIKVSWFRNDSELHESWKYNMSFINSVA 7347

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEK 2352
             L I     ED+G+Y  +A N +G  + + ++TV A   + ++   P G  K
Sbjct: 7348 LLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAP-PVFTQKPSPVGALK 7398



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   LK  + ++ G  V LE +V       + + WF++G  + +G + +S+F   + T
Sbjct: 7668 PSFIRKLKDVNAIL-GASVVLECRVSGSAP--ISVGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L+++ L   D+GIYTC A N+ G    +A + +++
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE 7759



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 43/157 (27%), Positives = 65/157 (41%), Gaps = 8/157 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG   + + W  +   I  S R          +LEIL +   D   YSC   N+ GQ +I
Sbjct: 7878 TGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQ-DI 7936

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L  V     + P F   ++++E +  G+ A  +C V     P+++I WY     +R 
Sbjct: 7937 CEALVSVL----EPPYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRS 7989

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +   K         L I    + D GEY C+A N  G
Sbjct: 7990 APAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVG 8026



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 2/95 (2%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  L    +  EG    LE +V   + P + + W+KN + +   +  + TF    + 
Sbjct: 9176 PSFTKRLSETVEETEGNSFKLEGRVAG-SQP-ITVAWYKNNIEIQPTSNCEITFKNNTLV 9233

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L +     +D+G+YTCK +N  G A+ T+SI I++
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE 9268



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 53/198 (26%), Positives = 84/198 (42%), Gaps = 17/198 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            +PP F      +  +SEG+  + + S    G + + I+W   G+ I+ S R    +A G 
Sbjct: 9271 KPPVFDQHLTPVT-VSEGE--YVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGT 9327

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK---SKGQKPR-------FTTHI 3155
             VLE+      DSG Y C+A+N  G      K+   DK   +   K         F +  
Sbjct: 9328 AVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEP 9387

Query: 3156 QNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYT 3214
            Q+I  + +  +A F   V    DP   ++W     + +    R+          L+I  T
Sbjct: 9388 QSIR-VVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDT 9444

Query: 3215 QNHDSGEYVCRAYNKYGE 3232
               DSG Y C A+N++GE
Sbjct: 9445 TKTDSGLYRCVAFNEHGE 9462



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 58/228 (25%), Positives = 97/228 (42%), Gaps = 14/228 (6%)

Query: 352  YLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRF 411
            +L++ +   S  +D     + D   + T + I   E A+  +FVK  QD +V E      
Sbjct: 2230 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIV--EGAVV-EFVKELQDIEVPESYSGEL 2286

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V+     E  W+ ND +++ +  + I  +  G   L + +VT  D G  + V   K 
Sbjct: 2287 ECIVSPENI-EGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFVIDGKK 2344

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
                  C+L +  K + +A   ++  S   V EG+ V L  + V   +    W KDG  +
Sbjct: 2345 TT----CKLKM--KPRPIA--ILQGLSDQKVCEGDIVQLEVK-VSLESVEGVWMKDGQEV 2395

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             P+  + I  D  +  L I      DA  Y  T   +  ST+ R  +Y
Sbjct: 2396 QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2443



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 2/101 (1%)

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
            Q +  +++KP F K ++  +      VHLE  +    D  + V W  +G+ +  G  +K 
Sbjct: 4562 QAELIIIDKPHFIKELEPVQSAINKKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYKI 4619

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             ++     L+I  A  +D+GTY+C A+N  G +  +++V V
Sbjct: 4620 CFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 4660



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 25/99 (25%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++ ++  P F + L  +++     VHLEC++    D+ + V W  +G+ +  G  ++  +
Sbjct: 4564 ELIIIDKPHFIKELEPVQSAINKKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICF 4621

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            E     L++     +DSG Y C A+N+ G +  S  + V
Sbjct: 4622 EDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 4660



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 3/94 (3%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            +P F+  L  +++     + H EC+V+   D  +T+ W  +GQK+  G  Y+   +    
Sbjct: 4570 KPHFIKELEPVQSAIN-KKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYKICFEDKIA 4626

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L+I     +DSGTY+C A+N+ G +  + T+ V
Sbjct: 4627 TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 4660



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 4/103 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR-TFCDFGFV 3478
            P F    S +  LR G++  FE ++T T  P ++V WY +G  + A  +   +F D G  
Sbjct: 5788 PQFIKKPSPVLVLRNGQSTTFECQITGT--PKIRVSWYLDGNEITAIQKHGISFID-GLA 5844

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
              +IS    E+SG Y+C A N+ G A  +  +KV+     I E
Sbjct: 5845 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE 5887



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 26/95 (27%), Positives = 52/95 (54%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  L   DK++ G  +++E +V       +  +WFK+G  ++T A+ +       V+
Sbjct: 6164 PSFTKKLTKMDKVL-GSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L +N+L  +D+  YTCK +N+ G+   +  + +++
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE 6255



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L + +  K+G+    EC++     P + + WF N  ++    +Y  +       
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSVAL 7348

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L I    AEDSG Y+C+A N +G+A  +  L V
Sbjct: 7349 LTINEASAEDSGDYICEAHNGVGDASCSTALTV 7381



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            + P F+ + K + N I G  V  EC++     + + V WF++G  +  G + +       
Sbjct: 7666 VPPSFIRKLKDV-NAILGASVVLECRVSG--SAPISVGWFQDGNEIVSGPKCQSSFSENV 7722

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L++  L   D+GIYTC A N+ G+DE S  LT
Sbjct: 7723 CTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLT 7756



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 3/100 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F + L     +S G ++ +EC++   G P + V WFH G  ++ G +++T       A
Sbjct: 8609 PSFTRKLKETNGLS-GSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 8665

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276
            L +     +D+G+YT  A N  GS   SA + V E    V
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV 8705



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 100/413 (24%), Positives = 169/413 (40%), Gaps = 43/413 (10%)

Query: 1262  HTSAIVRVIERSDIVTDTQNEQAIEQI-QLLEDAARRTKQVREDITVMQA-PQFSRALHN 1319
             HT+  V + +     + T  + +I+   Q+  +A   + + +  +TV++  P F+  L +
Sbjct: 12896 HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAK--LTVLEGDPYFTGKLQD 12953

Query: 1320  IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
                VE   V L+C +         V+WF +GK IK         +     L L      D
Sbjct: 12954 YTGVEKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSD 13010

Query: 1380  SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DTSRYKKTDIIDE 1438
              G YTC      G   TS  L +   +D  ++   P  L  ++ +E +T+R++ T+I ++
Sbjct: 13011 IGQYTCDC----GTDKTSGKLDI---EDREIKLVRP--LHSVEVMETETARFE-TEISED 13060

Query: 1439  SV----TIKPRFVTRPKSIENVIEGQ-H--VHFECKLEPVTD-----SNLKVEWFKNGQP 1486
              +     +K   + +    E   EG+ H  V   C+L+         +N+K       +P
Sbjct: 13061 DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKP 13120

Query: 1487  VTIGHRFRPIHDF----GYVALDIIDLIAEDSGI-YTCRAVNLVGTDEVSCRLTCRSTTD 1541
               IG   RP+ D     G  A    +L  ED  + +  +   L  +D+V  R   +  T 
Sbjct: 13121 RVIG-LLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTL 13179

Query: 1542  IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
              +R  + E   E +Q+     K H    V E   +    T  L++  ++EG  A  E   
Sbjct: 13180 TLRDVKLEDAGE-VQLTAKDFKTHANLFVKEPPVEF---TKPLEDQTVEEGATAVLE--- 13232

Query: 1602  IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
               VS    KV+W+ N   +    ++    +     L I  C PED  TYTC A
Sbjct: 13233 CEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 13285



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 2/117 (1%)

Query: 4598  DAECVVSLPATKDKPKPQTKAANAPPEIIEP-LKDKIVAE-GQAIEFSCKIVGKPLPTVQ 4655
             +A   +S P+    P         P   ++P  +D IV   G+       + GKPLPT++
Sbjct: 24526 NAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIE 24585

Query: 4656  WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             W +GDK I+ S   ++  T  +  L + +A   D G Y   A N AG  +    +KV
Sbjct: 24586 WLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV 24642



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +Q G D + ++ + G PRP ++W K+G+ L  + +  +  T   T L ++   K D G Y
Sbjct: 25250 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 25309

Query: 337   TLLAENPNGCIVTS-GYLAVESP 358
             T+ A N  G    +   + +E P
Sbjct: 25310 TVTATNSAGTATENLSVIVLEKP 25332



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/103 (32%), Positives = 50/103 (48%), Gaps = 2/103 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F+ + +S  V  +  V+ +  V       + I+W+++ K L SG       D  
Sbjct: 5691 VKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAP--MTIKWFKDNKELHSGAARSVWKDDT 5748

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
              SL++    A DSG YIC+  ND G   +KAT+  K+ P  I
Sbjct: 5749 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFI 5791



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 4/93 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L + + +K GD +  EC++     P + + WF N  ++ A  +YR T       
Sbjct: 6350 PKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDSVAV 6407

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            + +     EDSG ++C+A N  G    +C+ KV
Sbjct: 6408 IQMNNLSTEDSGDFICEAQNPAGS--TSCSTKV 6438



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P  +   + P  V+ G+   LEC++   G P + VEW+ +G+ +T   + K  +     
Sbjct: 6629 EPAVIVEKAGPMTVTVGETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKIS 6686

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273
            +L I+     D G YT +  N++G +  +A+V V +R+
Sbjct: 6687 SLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA 6724



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 25/67 (37%), Positives = 41/67 (61%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P + VEWYKDG+ +T+S +    F     SL I+ +  +DAG+YT +  N +G++  TA 
Sbjct: 6658 PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAV 6717

Query: 860  IRVAARS 866
            + V+ R+
Sbjct: 6718 VDVSDRA 6724



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 25/94 (26%), Positives = 54/94 (57%), Gaps = 2/94 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PPRF+ +L  +  V + +   +EC++     P +++ +Y +   +Q +++F ++F     
Sbjct: 8231 PPRFIKKLEPSRIVKQDEFTRYECKIGG--SPEIKVLWYKDETEIQESSKFRMSFVDSVA 8288

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             L++ +   ED+G+Y+ +A NA G  +S+ S+ V
Sbjct: 8289 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 8322



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 2/90 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P FSR L +++   G  V  +C +   G + + V W+ +GKP+K     + ++  +   L
Sbjct: 8984 PSFSRQLRDVQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNVQTSFLDNTATL 9041

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
            ++       +G Y+C ATN +G A +S  L
Sbjct: 9042 NIFKTDRSLAGQYSCTATNPIGSASSSARL 9071



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 4/106 (3%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            I I++ K  PP F   +   + V EG  V   C V+  G   +RI W   GR      R 
Sbjct: 9264 IVIKEPK-KPPVFDQHLTP-VTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRC 9319

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
                  G   L++  +   D+G+Y C+A+N  GS TT +K+T   K
Sbjct: 9320 SFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDK 9365



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 25/83 (30%), Positives = 42/83 (50%)

Query: 263   VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
             V  P +     +  +Q G D + +V +SG P+P +TW K+G  L  + +  +  + + TT
Sbjct: 24154 VIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 24213

Query: 323   LRVRNTQKSDSGHYTLLAENPNG 345
             L ++ T K D G Y +   N  G
Sbjct: 24214 LSIKETHKDDGGQYGITVANVVG 24236



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 93/202 (46%), Gaps = 33/202 (16%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK-HEIITTHNHTTLR 324
            PKI ++ ++  + +G+DA F+V++ G P P   W+KNG ++  S++ +      N   L 
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +R+    DS    + A N          +A E+ + +++  Q  Q IT TQ+ +      
Sbjct: 2138 IRDVTAEDSASIMVKAIN----------IAGETSSHAFLLVQAKQLITFTQELQD----- 2182

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                        V +++D     M  F+C  T  P+ +V W+ +  ++ +   ++ + ++
Sbjct: 2183 -----------VVAKEKDT----MATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSD 2225

Query: 445  SGNHALMITNVTLSDSGVVTCV 466
               H L I  +  SD+   +CV
Sbjct: 2226 RKVHFLSILTIDTSDAEDYSCV 2247



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 2/77 (2%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            + K GD+   EC +  S  P +++ WF N   LP+  +Y+ T   S   + + +   EDS
Sbjct: 6361 IVKAGDSSRLECKIAGS--PEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDS 6418

Query: 2844 GIYTCKATNSKGSATTS 2860
            G + C+A N  GS + S
Sbjct: 6419 GDFICEAQNPAGSTSCS 6435



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  LK+   ++ G    LE +V   +   + + WF     + +GA+ ++TF   + T
Sbjct: 6727 PSFTRRLKNTGGVL-GASCILECKVAGSSP--ISVAWFHEKTKIVSGAKYQTTFSDNVCT 6783

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L +NSL + D G YTC A N+ G     A + +++
Sbjct: 6784 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE 6818



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            ++P F     +I+ + G +   EC +   G Q MR+ W  + K I+ G  +      +  
Sbjct: 7196 KSPFFDIKPVSIDVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 7253

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             L +L V   DSG YTCQATN +G+ + S  L V
Sbjct: 7254 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 7287



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 2/100 (2%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            ++PPRF+ +++    + + E T++EC++   G P +KV W+ +   +   ++F   +   
Sbjct: 8229 QEPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDS 8286

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
               +    +  EDSG+Y C A N  G   +   +K    P
Sbjct: 8287 VAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 8326



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 3/83 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   L     L  G     EC+V     P +++ WFH G +I +G +Y+TT      A
Sbjct: 8609 PSFTRKLKETNGLS-GSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 8665

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L +      DSG Y C ATN  G
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAG 8688



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 5/195 (2%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
             ET E +++SE  L P  V +    DVT    T    +       ++T ++ + Q +    
Sbjct: 26212 ETTEPVKVSEPPLPPGRVTLV---DVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEK 26268

Query: 438   HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGET-AFQCRLNVIEKEQVVAPKFVER 496
                        A  I+ +T  +  V    A N+ G +   Q  + VI ++  + P     
Sbjct: 26269 WSTCTQVKTLEAT-ISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELP 26327

Query: 497   FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
             F T NV+  E + ++    G P   + W+KDG  +     + + +    ++L I  A   
Sbjct: 26328 FHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKE 26387

Query: 557   DAAWYQCTAQNVAGS 571
             D   Y+    N AGS
Sbjct: 26388 DVGTYELCVSNSAGS 26402



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 70/271 (25%), Positives = 100/271 (36%), Gaps = 31/271 (11%)

Query: 2339 SIISESQRPEGLEKI--RELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTAH 2395
            SI   + R E  E +  RE +  E  + P   E PVT   P     L+N+  I EG++  
Sbjct: 905  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTP--PTLVSGLKNVTVI-EGESVT 961

Query: 2396 FDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
             +C +     PT  V W+R +  IE S     T   G   + I     ED G + C A N
Sbjct: 962  LECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVN 1019

Query: 2456 LLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLT 2515
              G                + ET         +K     +R  E  D        T+   
Sbjct: 1020 EAGTVSTSCYLAVQVSEEFEKET-----TAVTEKFTTEEKRFVESRDVVMTDTSLTEEQA 1074

Query: 2516 GPSE--------------LWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            GP E              L EG    +  +V   G+P     W  +GV L  G R++ ++
Sbjct: 1075 GPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSY 1132

Query: 2562 D--FGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +   G   L I+   A+DAG Y     N+ G
Sbjct: 1133 NKQTGECKLVISMTFADDAGEYTIVVRNKHG 1163



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 4737 PAQFKTQITSKIKPT--IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            PA F+ ++T    PT  ++WL +G  +      +MI+E     L  G  Y  D+G  TCR
Sbjct: 1719 PAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCR 1778

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            AT   G   TSA L+VK +
Sbjct: 1779 ATNKYGTDHTSATLIVKDE 1797



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 4/100 (4%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            V  ++PP FV ++     ++  E+ +  C+L   G P ++V WF N K L   N     +
Sbjct: 4658 VTVREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYF 4715

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMD--ETKAVIK 4064
                  ++   V  EDSG Y C A N  G D   T+ VIK
Sbjct: 4716 VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK 4755



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 8/122 (6%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+P  FV +++    L + + T+  C++   G P +K+ WF N + +   ++    +   
Sbjct: 5223 KEPATFVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFVES 5280

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE 4089
               +    V  EDSGEY+C A N  G D   +++     P         K  K IE ++E
Sbjct: 5281 TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP------YFTKEFKPIEVLKE 5334

Query: 4090 ME 4091
             +
Sbjct: 5335 YD 5336



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 3/114 (2%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I K  P F +      P+   K   +    E  G P   + WF +   +  G ++KT+  
Sbjct: 5315 IVKESPYFTKEFK---PIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQ 5371

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAI 1285
               V+L I+   +AD GEY  R  N +GS+  SA V + E    +   ++  ++
Sbjct: 5372 DHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSL 5425



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 49/179 (27%), Positives = 76/179 (42%), Gaps = 16/179 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            + P F      +E LKE D        E    P   I WF +   +R+G +Y+T      
Sbjct: 5318 ESPYFTKEFKPIEVLKEYD---VMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHL 5374

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226
            V+L IL   A D+G Y C+ TN++G ++  C+ +V          + P+ ++KI    + 
Sbjct: 5375 VSLQILKFVAADAGEYQCRVTNEVGSSI--CSARVTLR-------EPPSFIKKIESTSSL 5425

Query: 2227 GHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAH--FECQVEPVHDPNLRIEFYHNGK 2283
               T       K S P  VT L+ +  + E       FE  V  ++     IE  H+GK
Sbjct: 5426 RGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSG--IEVKHDGK 5482



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 33/163 (20%), Positives = 64/163 (39%), Gaps = 7/163 (4%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E   I  G     I+WF +   + +  +           L +     + +G Y+C  TN 
Sbjct: 6275 EFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTND 6334

Query: 3129 WGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHN 3188
             G    +  L        + P+F   ++  + +K G S+  EC +     P++++ W+ N
Sbjct: 6335 VGSDSCTTMLLVT-----EPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRN 6387

Query: 3189 GQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               +  S + +        V+ +      DSG+++C A N  G
Sbjct: 6388 EHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAG 6430



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 2/98 (2%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V + P+F+ +L     +  G S+  EC+I   P+  +RV W+ N   L +  +YR +   
Sbjct: 6346 VTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPE--IRVVWFRNEHELPASDKYRMTFID 6403

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
              A + +  +  EDSG++ C+A N  G    S ++ V+
Sbjct: 6404 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 6441



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 3/109 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F+   + +  + G  + F + I   G P  K+ W +  + +    R    F   
Sbjct: 6816 VQEPPSFVKEPEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDT 6873

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQH 740
               L++ +++I  SGEYTC   +  G A     L V  P A ++R S H
Sbjct: 6874 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDH 6922



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/101 (28%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 1305 ITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++V + P+F + L   +   +G ++ LEC++   G   ++V WF N   +    ++  ++
Sbjct: 7285 LSVKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSF 7342

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
                  L +     EDSG Y C+A N +G+A  S AL V A
Sbjct: 7343 INSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 7383



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F   L++     +G+ + LE ++     P +K+ WF+N   L    +   +F  
Sbjct: 7287 VKEPPKFVKKLEASKVAKQGESIQLECKISG--SPEIKVSWFRNDSELHESWKYNMSFIN 7344

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             +  L+IN    +DSG Y C+A N +G+A  + ++ ++
Sbjct: 7345 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVK 7382



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P FV+ L       +G++I LEC++   G P ++V WF N   +    ++   +   
Sbjct: 7288 KEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINS 7345

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
               L I  A++ D+G+Y   A N +G A  S  + V
Sbjct: 7346 VALLTINEASAEDSGDYICEAHNGVGDASCSTALTV 7381



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F + L+     ++G++   +C++   G P +KV WFRN+  + +S +   +    
Sbjct: 7288 KEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINS 7345

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459
               +TI+    ED G Y+C A N +G+
Sbjct: 7346 VALLTINEASAEDSGDYICEAHNGVGD 7372



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V + P F   L+  + ++ G+   L+ +V+    P ++I W+K    L +    K  F  
Sbjct: 7943 VLEPPYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKN 7999

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             + +L IN + + D G Y+CKA N +G   S+A + I++R
Sbjct: 8000 NVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKER 8039



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I+  +G  VH +C ++  G P   + W+ + R   +G +   +++    ++ I  + A D
Sbjct: 8335 IETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAAD 8392

Query: 3765 AGEYTCRATNKWGSATTTAKITCSA 3789
             GEY C+ATN  GS T    I   A
Sbjct: 8393 IGEYQCKATNDVGSDTCVGSIALKA 8417



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            T  P F   LK TN +  G S   E +V     ++  V W+  G +I+S  + QT     
Sbjct: 8606 TVPPSFTRKLKETNGL-SGSSVVMECKVYGSPPIS--VSWFHEGNEISSGRKYQTTLTDN 8662

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              AL +  +   DSG YT +A N AG  + SA +TV
Sbjct: 8663 TCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 8698



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 25/72 (34%), Positives = 35/72 (48%)

Query: 4633  IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             I   G  I+    ++G+P PTV W KGD+++K ++      TA    L I+E    D G 
Sbjct: 22003 IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 22062

Query: 4693  YKCVAYNSAGRV 4704
             Y   A N  G V
Sbjct: 22063 YPLTARNIVGEV 22074



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 7/117 (5%)

Query: 1289 QLLEDAARRTKQVREDITVMQAPQ--FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEW 1346
            +LLE+       V  DI+  +A +  F   + N   +EG  V   C++   G    ++ W
Sbjct: 1269 ELLEEDGEEKMAV--DISESEAVESGFDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAW 1324

Query: 1347 FCNGKPIKTGHRFRPAYEFD-YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            + +GK IK G R++  +  D   +L +  V PED G+YT  A+N  G A+ S  L V
Sbjct: 1325 YKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1381



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 7/86 (8%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF---GFAALDILTVYG 1911
            ++ EG    + C++  YP P  ++ WY +GK ++ G RY+   DF   G A+L I  V  
Sbjct: 1301 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLP 1356

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            ED G YT  A N  G A+ S +L V+
Sbjct: 1357 EDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 96/395 (24%), Positives = 167/395 (42%), Gaps = 34/395 (8%)

Query: 1424 LEDTSRYK-KTDIIDESVTIKPRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLK-VE 1479
            L+D   Y  K      S  +K   V   K+++N  V E Q   F  +L   T  N+K V+
Sbjct: 2683 LDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL---THPNVKGVQ 2739

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W KNG  +    ++         +L I +    D  +Y  R    +G    S RL    T
Sbjct: 2740 WIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFR----LGRLGASARLHVE-T 2794

Query: 1540 TDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599
              I++  ++   LE   V  + S  H T  V        I   S K+  + E +      
Sbjct: 2795 VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEI-KPSDKHRLVSERKVHKLML 2853

Query: 1600 RLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPED-SGTYTCRA--I 1655
            + I  SDA    E+      L+  ++ F ET +      +I   +PE  + ++ C     
Sbjct: 2854 QNISPSDAG---EYTAVVGQLECKAKLFVETLHITKTMKNIE--VPETKTASFECEVSHF 2908

Query: 1656 NALGEAVTSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV---ITQAP 1711
            N     + +G+ I  S+K  I ++ +    +      ED+++Y      D+V   +T  P
Sbjct: 2909 NVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTP 2968

Query: 1712 VF-TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            +  T  +KDI   E     FE   + V    +  +WL+NGV I+++++          +L
Sbjct: 2969 IMITSMLKDINAEEKDTITFE---VTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSL 3025

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            N++ V+  D+  YT  A    G+A +++TL+V+++
Sbjct: 3026 NIRNVHFGDAADYTFVA----GKATSTATLYVEAR 3056



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 27/96 (28%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP FT  L++ D +V G    L+ ++       +++ WFK+G  +    R +  F  G  
Sbjct: 5039 APFFTKPLRNVDSVVNGT-CRLDCKIAGSLP--MRVSWFKDGKEIAASDRYRIAFVEGTA 5095

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            +L I  +  +D+G +TC+ATN +G   S+ ++ +++
Sbjct: 5096 SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE 5131



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V+++P FT   K  + L E   V L A+V     P  +I WFK+   L +G + K+    
Sbjct: 5316 VKESPYFTKEFKPIEVLKE-YDVMLLAEVAGT--PPFEITWFKDNTILRSGRKYKTFIQD 5372

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             LV+L I      D+G Y C+ TN +G ++ +A + + +
Sbjct: 5373 HLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLRE 5411



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)

Query: 630  EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            E +V  PP FI  LK V  ++   +  E  +   G P  ++ WLKN + I +S ++T   
Sbjct: 5875 ELKVKEPPTFIRELKPVEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTD 5932

Query: 690  RFGYISLDMLSLNIQDSGEYTC 711
            R    +L +   +  D+GEY C
Sbjct: 5933 RVSVFNLHITKCDPSDTGEYQC 5954



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 2/118 (1%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S + D      +   PP FT   + +     SS H EC++       +  +WF +GK + 
Sbjct: 6148 SSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEIS 6205

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            T ++ + +     V LE+  +   D   YTCK +N  G+   S  L VK     +++P
Sbjct: 6206 TSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKP 6263



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   L  +  + G  IH E ++   G   +  +W K+G+ I  S+++  +     +S
Sbjct: 6163 PPSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L++ +L ++D+  YTC+  +  G      +L V
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAGDDACSGILTV 6253



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 43/188 (22%), Positives = 72/188 (38%), Gaps = 8/188 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  PP F T  + + + + G     +  +   G   + + W+     +  +   RT +  
Sbjct: 7002 TLEPPYFVTELEPL-EAAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTN 7058

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
             +  L        DSG Y+C+A N  G A  S K     + +   P F   +++IE    
Sbjct: 7059 NVATLVFNKVNINDSGEYTCKAENSIGTA--SSKTVFRIQERQLPPSFARQLKDIEQTV- 7115

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G      C +       +++ WY +G  +R    ++T        L I  T    SG+Y 
Sbjct: 7116 GLPVTLTCRL--NGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYS 7173

Query: 3224 CRAYNKYG 3231
            C A N  G
Sbjct: 7174 CSASNPLG 7181



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPPKF+ +++      +G+S   E ++     P++KV WF N  +L    +Y       +
Sbjct: 7289 EPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSV 7346

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +L I     E+SG+Y C A N +G  S    L
Sbjct: 7347 ALLTINEASAEDSGDYICEAHNGVGDASCSTAL 7379



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 39/144 (27%), Positives = 67/144 (46%), Gaps = 5/144 (3%)

Query: 3371 NLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIE 3430
            N K T  EN    + L  G +G   +      ++  +   S      + P F   L    
Sbjct: 8184 NYKMTLVENTATLTVLKVG-KGDAGQYTCYASNIAGKDSCSAHLGVQEPPRFIKKLEPSR 8242

Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR-TFCDFGFVILEISPTYPED 3489
             +++ E   +E ++  +  P +KV WY +   ++  S+FR +F D    +LE+     ED
Sbjct: 8243 IVKQDEFTRYECKIGGS--PEIKVLWYKDETEIQESSKFRMSFVD-SVAVLEMHNLSVED 8299

Query: 3490 SGEYLCRAYNNYGEAVTTASMKVQ 3513
            SG+Y C A+N  G A ++ S+KV+
Sbjct: 8300 SGDYTCEAHNAAGSASSSTSLKVK 8323



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 2/95 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F  ++        E   FEC V   +   +++ W ++ + + SG +Y+  Y      
Sbjct: 9079 PPFFDIRLAPVDAVVGESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLENSAH 9136

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
            L +L V   DSG+Y C AVN+ G+D   A ++ K+
Sbjct: 9137 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE 9171



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 45/198 (22%), Positives = 82/198 (41%), Gaps = 5/198 (2%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRDVTEGKMT-RFDCRVTGRPYPEVTWFINDRQIRDDY 436
             ET E + I E    P+  +  + ++VT+  +T  ++          + + +  R I  + 
Sbjct: 17630 ETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 17689

Query: 437   NHKILVNESGNHALMITNVTLSDSGVVTCVARN--KSGETAFQCRLNVIEKEQVVAPKFV 494
              HK+  +   +    +  +   D+      A N    G+ +F C   +  K+++  P   
Sbjct: 17690 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSF-CTKPITCKDELAPPTLH 17748

Query: 495   ERF-STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
               F   L +R GE   L  R  G P P+++W KD   ++ +    I T      L+  +A
Sbjct: 17749 LDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKA 17808

Query: 554   KASDAAWYQCTAQNVAGS 571
             K SD+  Y    +N  GS
Sbjct: 17809 KRSDSGKYCVVVENSTGS 17826



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQKPRNSK---LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             V PP+I+  P+      +  G   +    + G P P + W K  Q L N+ + EI +T  
Sbjct: 23465 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDF 23524

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
              T+L V++  + DSG+Y L A+N  G
Sbjct: 23525 ATSLSVKDAVRVDSGNYILKAKNVAG 23550



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 2/130 (1%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           Q   T E +  +E A  P FV+  Q   V +G   R   RVTG P P V ++ +  +I+ 
Sbjct: 88  QATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             + +I   E   ++L+I      DSG  +  A N  G       L V  +E+V A K  
Sbjct: 147 SLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTK 205

Query: 495 ERFSTLNVRE 504
              ST  + E
Sbjct: 206 TIVSTAQISE 215



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F++ LQ +  +++G     + ++T +  PT  V++Y+DG  I +S            S
Sbjct: 104 PNFVQRLQSM-TVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I     ED+G+Y+V A N +G A STA + V     V A
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPA 201



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L S+  +++G +   + RV  I  P   + ++ +G +I++   ++ + +    +
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
            L I   Y EDSGTY   ATN +G A +T  L V G   +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 4/114 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYRTSNDFG 1900
            +AP+   ++   T + +G  AH+  R+   PDP    EWY NG K+ +S   Y    +  
Sbjct: 2076 EAPKIFERIQSQT-VGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERSDRIYWYWPEDN 2132

Query: 1901 FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
               L I  V  EDS     KAIN  G+  S   L VQ+K+ I    + +  + K
Sbjct: 2133 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2186



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 3/108 (2%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            E+ +   P FI +L  P + +  +  H EC+++   D  + V W  +G+ L  G  Y+  
Sbjct: 4564 ELIIIDKPHFIKELE-PVQSAINKKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKIC 4620

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
             +   A L+I     +DSG Y C A N  G +  S  + V+   S ++
Sbjct: 4621 FEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVK 4668



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L  +       +H EC V+  R  T  + W  + + LP G  YK   +    +L+I
Sbjct: 4573 FIKELEPVQSAINKKVHLECQVDEDRKVT--VTWSKDGQKLPPGKDYKICFEDKIATLEI 4630

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +DSG Y C A+N  GS++ S ++
Sbjct: 4631 PLAKLKDSGTYVCTASNEAGSSSCSATV 4658



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 7/169 (4%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP FT PL N++++  G     + ++  +    ++V W+ +GK + A  R+R     G  
Sbjct: 5039 APFFTKPLRNVDSVVNG-TCRLDCKIAGSLP--MRVSWFKDGKEIAASDRYRIAFVEGTA 5095

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
             LEI      D+G + CRA N+ G   ++ ++ VQ   + + +      + G+   +   
Sbjct: 5096 SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGS--AVCLK 5153

Query: 3539 EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
              + G+   LT     GN  E  +  S  I  E   +  E  L+  +DS
Sbjct: 5154 STFQGST-PLTIRWFKGN-KELVSGGSCYITKEALESSLELYLVKTSDS 5200



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  LK  D  ++G  + LE  V   + P + I+WFK+   ++   + K +F      
Sbjct: 5602 PSFTKKLKKMDS-IKGSFIDLECIVAG-SHP-ISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L I+ L   DSG YTC ATN  G    +  + +++
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE 5693



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 12/143 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+F+ +P  +  +  GQ   FEC++       ++V W+ +G  +T   +       G   
Sbjct: 5788 PQFIKKPSPVLVLRNGQSTTFECQITGTP--KIRVSWYLDGNEITAIQKHGISFIDGLAT 5845

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
              I     E+SG Y C A N  GT   S  L  +     +R       L+ ++V+    K
Sbjct: 5846 FQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE------LKPVEVV----K 5895

Query: 1564 YHRTDMVDEVTTQAPICTTSLKN 1586
            Y   ++  EVT   P   T LKN
Sbjct: 5896 YSDVELECEVTGTPPFEVTWLKN 5918



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 44/186 (23%), Positives = 69/186 (37%), Gaps = 7/186 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-IRDDYNHKILVNESGNHAL 450
            P+FV       V  G+       + G     V W     + IR+  N +I   E+    L
Sbjct: 6537 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVA-TL 6595

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
                   +++G   C  +N  G       L V+E   +V     E+   + V  GE   L
Sbjct: 6596 QFAKAEPANAGKYICQIKNDGGMEENMATLMVLEPAVIV-----EKAGPMTVTVGETCTL 6650

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              +  GTP   + W KDG  +  + + +       S+L I   +  DA  Y    QN  G
Sbjct: 6651 ECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVG 6710

Query: 571  STATRA 576
             ++  A
Sbjct: 6711 KSSCTA 6716



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 13/143 (9%)

Query: 1937 QSKESIIRDSQHESALEKIQY-LEDDSRYKRAVQDDS---------FVVEKPQFGKPIKN 1986
            QS+   I  ++  + LE ++  +ED ++Y   +++++          V+E P F +P+++
Sbjct: 7896 QSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEH 7955

Query: 1987 AEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAED 2046
             E   G P  L+  +     P +R+ WY     ++    +K  +     +L I      D
Sbjct: 7956 VEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSD 8013

Query: 2047 TGTYMCKATNAVGEAVTTSSVKV 2069
             G Y CKA N+VG AV +S+V V
Sbjct: 8014 VGEYSCKADNSVG-AVASSAVLV 8035



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D+  PP F  +++ +T+ +   +   EC++   G P + V WF  G  +    ++     
Sbjct: 8604 DRTVPPSFTRKLK-ETNGLSGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLT 8660

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                A+    +   DSG+Y C ATN+ G DE  A +     P  V
Sbjct: 8661 DNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV 8705



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G ++  EC V  S  P + + WF     + SG +Y++T   +  +L +    E DSG YT
Sbjct: 8623 GSSVVMECKVYGS--PPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYT 8680

Query: 2848 CKATNSKGSATTSGSL 2863
            C ATN  GS   S  L
Sbjct: 8681 CIATNMAGSDECSAPL 8696



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 41/115 (35%), Positives = 54/115 (46%), Gaps = 10/115 (8%)

Query: 467   ARNKSGETAFQCRLNVIEKEQVVAPKFVERFS----TLNVREGEPVVLNARAVGTPTPRI 522
             A N+ GE+     LNV+ ++  V P    R S    T+ V+ GEPV + A   G P P+I
Sbjct: 16298 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 16357

Query: 523   TWQKDGVPI-IPNPELRIHTD----GGAST-LDIPRAKASDAAWYQCTAQNVAGS 571
              W K+   I  P   L+I  +      A T L IP+A   D   Y  TA N  GS
Sbjct: 16358 EWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS 16412



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 2/125 (1%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +PP   Q+ ++  +++G+  + QV+++G P P V ++++G  + +S   +I    +  +L
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +      DSG Y++ A N  G   ++  L V+   E  V  ++++ I  T Q     + 
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG--EEEVPAKKTKTIVSTAQISESRQT 219

Query: 384 EISEK 388
            I +K
Sbjct: 220 RIEKK 224



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 3/102 (2%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            KP F+   + +++ I  + VH EC+++   D  + V W K+GQ +  G  ++   +    
Sbjct: 4570 KPHFIKELEPVQSAIN-KKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIA 4626

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVR 1544
             L+I     +DSG Y C A N  G+   S  +T R     V+
Sbjct: 4627 TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVK 4668



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 2/80 (2%)

Query: 3851 CRVEPKEDPKL--RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
            CR++ K    L  R+ W+++GK + +  RYR  +  G  SL+I+ V   D+G + CRA N
Sbjct: 5057 CRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATN 5116

Query: 3909 DFGEDFTKATISCKKLPDII 3928
              G   +   +  ++ P  +
Sbjct: 5117 SVGSKDSSGALIVQEPPSFV 5136



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 51/224 (22%), Positives = 90/224 (40%), Gaps = 19/224 (8%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    +    +  G  A ++A+L   G   + + W  +   I     IR  +   + 
Sbjct: 5412 PPSFIKKIESTSSLRGGTAA-FQATL--KGSLPITVTWLKDSDEITEDDNIRMTFENNVA 5468

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L + G +    G Y C+A N  G    S  L     S  +    T    +I+ +  G  
Sbjct: 5469 SLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL-----SVKEPATITEEAVSID-VTQGDP 5522

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A  +  V      ++  +W+ +GQ +   ++ K        +L I  T+  DSGEY    
Sbjct: 5523 ATLQ--VKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEV 5580

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLA-KIRELESLQGA 3269
             N  G    +A IN        L+ + P S   K+++++S++G+
Sbjct: 5581 QNDVGRSSCKARIN-------VLDLIIPPSFTKKLKKMDSIKGS 5617



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 35/119 (29%), Positives = 51/119 (42%), Gaps = 2/119 (1%)

Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314
            DS   I +L +  G      +    EPP+FI +   V  L  GQS  FE ++     P +
Sbjct: 5761 DSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGT--PKI 5818

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
            +V W+ +G ++    ++      G+    I     ENSG Y C A N  G  S    LK
Sbjct: 5819 RVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELK 5877



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 4/103 (3%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++ V + P F R L  +E V+ ++V LEC +   G     V W  N + I++  ++    
Sbjct: 5875 ELKVKEPPTFIRELKPVEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTD 5932

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
                  L +    P D+G Y C  +N+ G    SC+ RV  K+
Sbjct: 5933 RVSVFNLHITKCDPSDTGEYQCIVSNEGGSC--SCSTRVALKE 5973



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 11/126 (8%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            +V  P + + + KS  V E + +  EC V     P+L+++W ++GK +     +   ++ 
Sbjct: 6063 LVQEPAQIVEKAKSVDVTEKDPMTLECVVAGT--PELKVKWLKDGKQIVPSRYFSMSFEN 6120

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
               S  I  V  +DSG+Y  +  NDFG        SC     ++ QN  P   K+   LT
Sbjct: 6121 NVASFRIQSVMKQDSGQYTFKVENDFGSS------SCDAYLRVLDQNIPPSFTKK---LT 6171

Query: 3945 QMEATI 3950
            +M+  +
Sbjct: 6172 KMDKVL 6177



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 25/98 (25%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V + P FS     +ET++   V LEC L   G     V W+ + + +++  +++ A +
Sbjct: 6438 VIVKEPPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASK 6495

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
              + ++ +L+V   D G Y C+A N++G     C +++
Sbjct: 6496 NFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL 6533



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 4/107 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRF 1359
            + R  +TV + P F +    +E + G NV     ++  G    +V WF   + +  G R 
Sbjct: 6809 ECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRC 6866

Query: 1360 RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
               +E     L+L ++    SG YTC  +N  G+A  SC  R+  K+
Sbjct: 6867 NIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQA--SCTTRLFVKE 6911



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+T L  LE    GD    +C+V     P +T+ W+    K+R    YRT        
Sbjct: 7006 PYFVTELEPLE-AAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTNNVAT 7062

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L        DSG Y CKA N +G A +    ++
Sbjct: 7063 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRI 7095



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 4/125 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L   +  ++GE+   E +++ +  P +KV W+ N   L    ++         +
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGS--PEIKVSWFRNDSELHESWKYNMSFINSVAL 7348

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            L I+    EDSG+Y+C A+N  G+A  + ++ V+    +  +   P G     D I   E
Sbjct: 7349 LTINEASAEDSGDYICEAHNGVGDASCSTALTVKAP-PVFTQKPSPVGALKGSDVILQCE 7407

Query: 3540 GYSGT 3544
              SGT
Sbjct: 7408 -ISGT 7411



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 25/97 (25%), Positives = 51/97 (52%), Gaps = 2/97 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV   P F++    +  ++G++V L+C +   G     V W  + K ++   +F+   +
Sbjct: 7379 LTVKAPPVFTQKPSPVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSK 7436

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
                +L +L++   D G Y C+ATN++G    SC+++
Sbjct: 7437 HFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVK 7473



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 52/228 (22%), Positives = 90/228 (39%), Gaps = 13/228 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F     D +D+  G    + +  I  G     + WF     +    R        + 
Sbjct: 8701 PPSFVQK-PDPMDVLTGTNVTFTS--IVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVA 8757

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LE+    T+ SG Y+C  +N+ G+A  +  L     +K     F   + N   ++ G+ 
Sbjct: 8758 ELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAK-----FVKRL-NDYSIEKGKP 8811

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               E T      P + + W  NG  +  S R    +     +L+I  +   D+G+Y C  
Sbjct: 8812 LILEGTFTGT--PPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYI 8869

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
             N  G+D   A I    +   +++ L+P  ++ + +  SLQ     TP
Sbjct: 8870 ENASGKDSCSAQILIL-EPPYFVKQLEPVKVS-VGDSASLQCQLAGTP 8915



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 4/117 (3%)

Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK 3870
            +E     D+   + ++  PP F+ Q++   V   +    +C++     P++ + WY+   
Sbjct: 8869 IENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGT--PEIGVSWYKGDT 8926

Query: 3871 LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE--DFTKATISCKKLP 3925
             L     Y+  +     +L    V   DSGEYIC+A N  GE    T  T+  +KLP
Sbjct: 8927 KLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLP 8983



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 35/110 (31%), Positives = 56/110 (50%), Gaps = 6/110 (5%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            L EGQ+    C+   +  PN++ EW+ NG++L+   R++T  +     L I  V  ED G
Sbjct: 9683 LKEGQTCTMTCQ---FSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQG 9739

Query: 1916 EYTCKAINNLGQAVSSIRLN-VQSKESI--IRDSQHESALEKIQYLEDDS 1962
            +YTCK  +    A   I    +Q  + I  I  S+H+SA  + +   DD+
Sbjct: 9740 QYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDA 9789



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L ++  +R+G     + R+T    P +K  +Y +G  +++   F+   +     
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            L I+  YPEDSG Y   A N+ G A +TA + VQG+  +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 56/259 (21%), Positives = 98/259 (37%), Gaps = 12/259 (4%)

Query: 2887 VEQAEEARLAKGRRPSVPDTEYP-KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKI 2945
            V    EA++ +  R   P  E P  P  ++       ++EG+ + LE  +     P   +
Sbjct: 918  VLHGREAKVTETARVPAP-VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT--V 974

Query: 2946 EWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS 3005
             WY     +E    F++T   G   L + + +  DSG +TC A N+ G   TS  +    
Sbjct: 975  TWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 1034

Query: 3006 KDNLIERT---QHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD-IS 3061
             +   + T        TE    +++ +  +      +     G P     + K +V  + 
Sbjct: 1035 SEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLV 1094

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTTDSG 3119
            EG    +   +   G+    + W  +G  +   +R +  Y    G   L I  T   D+G
Sbjct: 1095 EGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1152

Query: 3120 TYSCRATNKWGQAEISVKL 3138
             Y+    NK G+   S  L
Sbjct: 1153 EYTIVVRNKHGETSASASL 1171



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            SD+   E ++  PP FI  ++   +        +C V         I W+++ K + S  
Sbjct: 4745 SDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSK 4802

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +YR       V L+I    + D GEY C   N+ G+    AT   K+ P  +
Sbjct: 4803 KYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFV 4854



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 3/101 (2%)

Query: 3826 VSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  P  F+ +++ S  +++ +  +  C+V     P ++I W+ N + +    ++R  +  
Sbjct: 5222 VKEPATFVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVE 5279

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L +  V  EDSGEY+C A N+ G D   + +  K+ P
Sbjct: 5280 STAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 5320



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 5/112 (4%)

Query: 3542 SGTVDTLTPEAES--GNPPEFTTTPSD-LILSENSSAHFECRLIPVNDSSMRVEWFHNGK 3598
            S  V T T +A      PP+F   PS  L+L    S  FEC++       +RV W+ +G 
Sbjct: 5770 SNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGN 5827

Query: 3599 PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             +    +       G    +I G    ++G Y C+A N  G A+ S +L+VK
Sbjct: 5828 EITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 5879



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 12/171 (7%)

Query: 1973 FVVEKPQF-GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031
            FV E PQF  KP     +  G     E  +T    P +RV WY +G  +    +   ++ 
Sbjct: 5783 FVKEPPQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFI 5840

Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQEL 2091
             G     I  A  E++GTY+C+A N  G A  +  +KV  +   ++  L    + K  ++
Sbjct: 5841 DGLATFQISGARVENSGTYVCEARNDAGTASCSIELKV-KEPPTFIRELKPVEVVKYSDV 5899

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLT 2142
            E       +E E  G  P  +T L +   ++   +     RV   N  H+T
Sbjct: 5900 E-------LECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN-LHIT 5942



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 39/170 (22%), Positives = 74/170 (43%), Gaps = 9/170 (5%)

Query: 411  FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM-ITNVTLSDSGVVTCVARN 469
            F   + G P  ++ WF +D ++      K  +   G+ + + + +V  S +G  TC   N
Sbjct: 6276 FKAILKGTPPFKIKWFKDDVELVS--GPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTN 6333

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLN-VREGEPVVLNARAVGTPTPRITWQKDG 528
              G  +    L V E      PKFV++      V+ G+   L  +  G+P  R+ W ++ 
Sbjct: 6334 DVGSDSCTTMLLVTEP-----PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNE 6388

Query: 529  VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +  + + R+      + + +      D+  + C AQN AGST+   ++
Sbjct: 6389 HELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV 6438



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 2/95 (2%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            +V  P   + +    TV   E    EC+V     P+L +EWY++GKLL S  +++  +  
Sbjct: 6626 MVLEPAVIVEKAGPMTVTVGETCTLECKVAGT--PELSVEWYKDGKLLTSSQKHKFSFYN 6683

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               SL IL V  +D+G Y  +  N+ G+    A +
Sbjct: 6684 KISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVV 6718



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FV  L  P   + G ++ L+C++   G P + V W+     +     ++TY+      
Sbjct: 7006 PYFVTELE-PLEAAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTNNVAT 7062

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            L        D+GEYT +A N +G+A +  + R+ ER
Sbjct: 7063 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 7098



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 2/90 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F+R L +IE   G  V L CRL   G   ++V W+ +G  ++     + ++  +   L
Sbjct: 7102 PSFARQLKDIEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDDENLQTSFVDNVATL 7159

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
             +L      SG Y+C A+N LG A +S  L
Sbjct: 7160 KILQTDLSHSGQYSCSASNPLGTASSSARL 7189



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V+V + P FI  L     +  G+ A  +C+++  P+  +R+ WY     L+S   Y+   
Sbjct: 7941 VSVLEPPYFIEPLEHVEAVI-GEPATLQCKVDGTPE--IRISWYKEHTKLRSAPAYKMQF 7997

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
                A+L I  V   D GEY+CKA N++G   SS  L ++ ++
Sbjct: 7998 KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERK 8040



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 67/249 (26%), Positives = 101/249 (40%), Gaps = 20/249 (8%)

Query: 3276 TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH 3335
            T    PP F  ++  V  +V G+SA FE  +       +KV W  + +++  G +Y+  +
Sbjct: 9074 TEGKNPPFFDIRLAPVDAVV-GESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISY 9130

Query: 3336 DFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDS---QLPRGMEG 3392
                  L +L   + +SG+Y C A N++G+DS  A L    KE LI  S   +L   +E 
Sbjct: 9131 LENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI--KERLIPPSFTKRLSETVEE 9188

Query: 3393 GLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNL 3452
                   LE  +   +  +V   K    +   P SN E   +      + R    +D  L
Sbjct: 9189 TEGNSFKLEGRVAGSQPITVAWYKNNIEI--QPTSNCEITFKNNTLVLQVRKAGMNDAGL 9246

Query: 3453 KVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
                Y    S  AGS     C    VI E  P  P    ++L     + GE V   S  V
Sbjct: 9247 ----YTCKVSNDAGS---ALCTSSIVIKE--PKKPPVFDQHLTPVTVSEGEYV-QLSCHV 9296

Query: 3513 QGKRNIILE 3521
            QG   I ++
Sbjct: 9297 QGSEPIRIQ 9305



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 42/179 (23%), Positives = 78/179 (43%), Gaps = 21/179 (11%)

Query: 1690 QLEDTSKYQR----HSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
            QL+D   Y+     H A  ++    P +   ++D+ + E Q      +      P ++ E
Sbjct: 9647 QLKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQF---SVPNVKSE 9703

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W RNG  ++   R  T  +     L +  V  ED G YTC+  +            +++ 
Sbjct: 9704 WFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYED------------LETS 9751

Query: 1806 ASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHY 1864
            A L++E++     ++IQ +  S       + EV+ + A   +T   GPT+L+E Q  ++
Sbjct: 9752 AELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDA--IVTWYKGPTELTESQKYNF 9808



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 4/114 (3%)

Query: 4603  VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
             VSLP   +    + K    PP+I+ P +  I A G+ +     + GKP PT +W KG+  
Sbjct: 19808 VSLPREAEGVY-EAKEQLLPPKILMPEQITIKA-GKKLRIEAHVYGKPHPTCKWKKGEDE 19865

Query: 4663  IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  S +  + +      L I +   +D G Y   A NS+G  T   K+KV   D
Sbjct: 19866 VVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG--TDTQKIKVVVMD 19917



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 11/122 (9%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKT 2428
            +T Q P FTQPLQ++  + EG TA F+  +   G P  +V WFR+ ++I  S+   +  +
Sbjct: 1    MTTQAPTFTQPLQSV-VVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQIS 57

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ 2488
               G   +TI  V   + G Y  +A+N  G+              ++ ET  P  ++++Q
Sbjct: 58   FSDGRAKLTIPAVTKANSGRYSLKATNGSGQ------ATSTAELLVKAETAPPNFVQRLQ 111

Query: 2489 KL 2490
             +
Sbjct: 112  SM 113



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 5/98 (5%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDF 2697
            QAP FT  L+S   ++EG     EA +     P  ++ WF++G  ++T     ++ +F  
Sbjct: 4    QAPTFTQPLQSV-VVLEGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G   L+I ++   +SG Y+ KATN  G+A STA + ++
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/79 (32%), Positives = 40/79 (50%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G  A     +    KP IQW   G L+  + D++ + +G++  L+I  T  ED G +TC 
Sbjct: 3517 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 3576

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            A+   G+   SA L + SK
Sbjct: 3577 ASNDYGKTICSAYLKINSK 3595



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L + V +EGD +H   ++  +++    + W+F NK +PS  ++K   D +  +L I    
Sbjct: 4295 LVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVN 4350

Query: 2840 EED-SGIYTCKATNSKGSATTSGSL 2863
             ED  G Y C+A N  G   TS  L
Sbjct: 4351 TEDHQGEYVCEALNDSGKTATSAKL 4375



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 3/115 (2%)

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            + L DS +      + V    AP    ++  P +++ G  A + C I+  P  N+R +W+
Sbjct: 4361 EALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSAP--NVRFQWF 4417

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
              G+ +    +    +    ++L+IL     D GEYTCKA N  G    +  L V
Sbjct: 4418 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4472



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 2/98 (2%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +  P FV+ +     +  G++  L C+L+  G P ++V WF N + ++  +  + Y+   
Sbjct: 4661 REPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNS 4718

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               LDI      D+G Y+  AVN +GS   S  + + E
Sbjct: 4719 EAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE 4756



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F KP++N +        L+  +       MRV W+ +G+ +    R++  +  G  +L
Sbjct: 5040 PFFTKPLRNVDSVVNGTCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 5097

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +I+     D G + C+ATN+VG   ++ ++ V
Sbjct: 5098 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 5129



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 13/151 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+   + +  L+ G    FEC++     P + + W+ +G +I A  ++  +   G   
Sbjct: 5788 PQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 5845

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGH 2228
              I     E+SGTY+C+A N  G A  +  LKV          + P  + +++ +E   +
Sbjct: 5846 FQISGARVENSGTYVCEARNDAGTASCSIELKV---------KEPPTFIRELKPVEVVKY 5896

Query: 2229 STRIEVE-EPKISPPRFVTELRGTTHVFEGK 2258
            S  +E+E E   +PP  VT L+    +   K
Sbjct: 5897 SD-VELECEVTGTPPFEVTWLKNNREIRSSK 5926



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  P Q +   KSV   E   +  E  +   G P +K++WLK+G+ I  S  F+  F   
Sbjct: 6064 VQEPAQIVEKAKSVDVTEKDPMTLECVV--AGTPELKVKWLKDGKQIVPSRYFSMSFENN 6121

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
              S  + S+  QDSG+YT +  +  G +   A L V
Sbjct: 6122 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV 6157



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 12/194 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F++ F  IV+  +      E  L  +G     + W+ + + + +S + +        
Sbjct: 6443 PPVFSS-FPPIVETLKNAEVSLECEL--SGTPPFEVVWYKDKRQLRSSKKYKIASKNFHT 6499

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             + IL   T+D G Y C+A N+ G    S    C  K K + PRF + + ++  +  G+ 
Sbjct: 6500 SIHILNVDTSDIGEYHCKAQNEVG----SDTCVCTVKLK-EPPRFVSKLNSLTVVA-GEP 6553

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPM-RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            A  + ++       + ++W    + + R S  I+         L  A  +  ++G+Y+C+
Sbjct: 6554 AELQASIEGAQP--IFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQ 6611

Query: 3226 AYNKYGEDFTRATI 3239
              N  G +   AT+
Sbjct: 6612 IKNDGGMEENMATL 6625



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 23/66 (34%), Positives = 39/66 (59%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P L +EW+K+G  LT+  + K +F   + +L I S+   D+G YT +  N +G++  TA 
Sbjct: 6658 PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAV 6717

Query: 2732 IKIEDR 2737
            + + DR
Sbjct: 6718 VDVSDR 6723



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/146 (23%), Positives = 60/146 (41%), Gaps = 4/146 (2%)

Query: 1403 IAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESV-TIKPRFVTRPKSIENVIEGQH 1461
            I+   ++   +  +G    Q   +  +   T ++D S   + P F  R K+   V+ G  
Sbjct: 6685 ISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVL-GAS 6743

Query: 1462 VHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
               ECK+     S + V WF     +  G +++         L +  L + D G YTC A
Sbjct: 6744 CILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVA 6801

Query: 1522 VNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
             N+ G+DE    LT +     V+  +
Sbjct: 6802 ANVAGSDECRAVLTVQEPPSFVKEPE 6827



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 44/199 (22%), Positives = 81/199 (40%), Gaps = 10/199 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G     + WF   + +    R    +   +  LE+     + SG Y+C  +N  GQA  +
Sbjct: 6845 GTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCT 6904

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
             +L   + +   K R + H      ++ G+S   E T        + + W  +G  +  S
Sbjct: 6905 TRLFVKEPAAFLK-RLSDH-----SVEPGKSIILESTY--TGTLPISVTWKKDGFNITTS 6956

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD 3255
             +   V+     +L+I  +   D+G+Y C   N+ G D   A ++   +   ++  L+P 
Sbjct: 6957 EKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTL-EPPYFVTELEPL 7015

Query: 3256 SLAKIRELESLQGAQQQTP 3274
              A + +  SLQ     TP
Sbjct: 7016 E-AAVGDSVSLQCQVAGTP 7033



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 3/97 (3%)

Query: 633  VYPPPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V  PP+F+  L+ S  A +G  I  E +I   G P +K+ W +N   +  S ++   F  
Sbjct: 7287 VKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFIN 7344

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
                L +   + +DSG+Y C A +  G A     L V
Sbjct: 7345 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTV 7381



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/113 (28%), Positives = 48/113 (42%), Gaps = 3/113 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP FT    +      SS   EC++       + V WFH G  + +G + +T        
Sbjct: 8608 PPSFTRKLKETNGLSGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 8665

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGT 3669
            L +  + + D+G YTC ATN  G    S  L V+     + +P  P    +GT
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPD-PMDVLTGT 8717



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F + L  V A+ G    FE  +   G   +K+ W K+ + I +  ++   +      
Sbjct: 9079 PPFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAH 9136

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L +L ++  DSG+YTC AV+  G     A L++  R
Sbjct: 9137 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 9172



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 34/151 (22%), Positives = 66/151 (43%), Gaps = 4/151 (2%)

Query: 195   GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIST 254
             GY T    + Q       T++S   D  +     +  ++  FR +  +  VG S  + + 
Sbjct: 19759 GYITSYREEEQPA--DRWTEYSVVKDLSLVVTGLKEGKKYKFRVA-ARNAVGVSLPREAE 19815

Query: 255   EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
              +  +   + PPKI   P    ++ G   + +  + G P P   W K    ++ S+   +
Sbjct: 19816 GVYEAKEQLLPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 19874

Query: 315   ITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 + + L +++  + DSG+Y+L AEN +G
Sbjct: 19875 HKADSSSILIIKDVTRKDSGYYSLTAENSSG 19905



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 25/81 (30%), Positives = 41/81 (50%)

Query: 498   STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
             S L V+ G  V L+A   G P P ++W+KDG  + P   +++       TL++      D
Sbjct: 20230 SLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKD 20289

Query: 558   AAWYQCTAQNVAGSTATRARL 578
             +  Y  TA+N +GS +   +L
Sbjct: 20290 SGDYTITAENSSGSKSATIKL 20310



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 46/142 (32%), Positives = 67/142 (47%), Gaps = 15/142 (10%)

Query: 4580  DSGKYE--CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP-LKDKI-VA 4635
             + GKYE    A N+AG     +E   ++   KD+ +       AP  +++P +KD + + 
Sbjct: 21267 EGGKYEFRIRAKNTAGAISAPSESTETI-ICKDEYE-------APTIVLDPTIKDGLTIK 21318

Query: 4636  EGQAIEFSC-KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694
              G  I  +   I+GKPLP   W K  K I+PS   Q++ T     L I  A  +D G+Y 
Sbjct: 21319 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 21378

Query: 4695  CVAYNSAGRVTVAAKLKVTQPD 4716
               A N  G  T    +KVT  D
Sbjct: 21379 ITATNPFG--TKVEHVKVTVLD 21398



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E +PP F Q  ++    QG   + + ++ G PTPVV + R  A +     + +    Q G
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQI---SQEG 156

Query: 128 DV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           D+ SLLI +  P D G Y+  A N  G A  +  +  +G
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L ++  ++G  +  +  V  +  PT  ++++ +   + S   ++ + +    SL I
Sbjct: 106  FVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               Y EDSG Y+  ATNS G AT++  L   G++ +    +  +       + ++ + R+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV--PAKKTKTIVSTAQISESRQTRI 221

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923
             K              E +I  AA  QL
Sbjct: 222  EKKIEAHFDARSIATVEMVIDGAAGQQL 249



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 14/128 (10%)

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866
            KI+E E G I +   + P++ TP      +     EE + V     +   ++    + WY
Sbjct: 4275 KIQEAEGGFIKE---DGPMIHTP------LVDTVSEEGDIVHLTTSITNAKE----VNWY 4321

Query: 3867 RNGKLLPSGHRYRTVYDMGFVSLDILYVYAED-SGEYICRAVNDFGEDFTKATISCKKLP 3925
               KL+PS  +++ + D    +L I  V  ED  GEY+C A+ND G+  T A ++  K  
Sbjct: 4322 FENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 4381

Query: 3926 DIILQNQV 3933
              +++ ++
Sbjct: 4382 APVIKRKI 4389



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   LK + +++G  I  E  +   G   + I+W K+ Q I AS ++   F      
Sbjct: 5601 PPSFTKKLKKMDSIKGSFIDLECIV--AGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 696  LDMLSLNIQDSGEYTCRAVSATG 718
            L++  L   DSG YTC A +  G
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAG 5681



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 3/130 (2%)

Query: 3249 LESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVP 3308
            L S + D+     E+E+  G         + EPP F+T+++ +   V G S   + ++  
Sbjct: 6973 LNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAV-GDSVSLQCQVAG 7031

Query: 3309 VDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDST 3368
               P++ V W+    KL     YRT+    +  L        +SGEY C A N +G  S+
Sbjct: 7032 T--PEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASS 7089

Query: 3369 KANLKCTSKE 3378
            K   +   ++
Sbjct: 7090 KTVFRIQERQ 7099



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 29/97 (29%), Positives = 43/97 (44%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            P   P    KP +  +  G  A F+  ++G    R+TW K+ + +     + I    N  
Sbjct: 7194 PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 7253

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             LR+    K DSG YT  A N  G  + S  L+V+ P
Sbjct: 7254 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 7290



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G+SA +EC +     P MR+ W  + K ++ G  Y  +       L IL V   DSG+YT
Sbjct: 7212 GESADFECHVTG-AQP-MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYT 7269

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIR 1944
            C+A N++G+ + S +L+V+     ++
Sbjct: 7270 CQATNDVGKDMCSAQLSVKEPPKFVK 7295



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 3/110 (2%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   LK   + + G  V  E ++   ++P L++ W+K+GV L   A L+++F   + T
Sbjct: 8043 PFFARKLKDVHETL-GFPVAFECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVAT 8099

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLD 2751
            L I        G Y C A+N LG A S+A + + +        L P S+D
Sbjct: 8100 LQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVD 8149



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 64/264 (24%), Positives = 106/264 (40%), Gaps = 39/264 (14%)

Query: 1943 IRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLT 2002
            I  S  E A +   Y+E+ S  K +      ++E P F K ++  +V+ G    L+  L 
Sbjct: 8854 IPSSTVEDAGQYNCYIENASG-KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLA 8912

Query: 2003 PVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAV 2062
                P + V WY     ++    +K  +      L        D+G Y+CKA N+VGE  
Sbjct: 8913 --GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGE-- 8968

Query: 2063 TTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLK 2122
                  V A + L   T+ EQ+L        + R     +E  G   VF  A++      
Sbjct: 8969 ------VSASTFL---TVQEQKLP-----PSFSRQLRDVQETVGLPVVFDCAISG----- 9009

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
                       EPI+     + W+ +G+ ++     +T+       L+I  T    +G Y
Sbjct: 9010 ----------SEPIS-----VSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQY 9054

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRN 2206
             C ATN +G A ++  L +   +N
Sbjct: 9055 SCTATNPIGSASSSARLILTEGKN 9078



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/100 (33%), Positives = 52/100 (52%), Gaps = 4/100 (4%)

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
            +++EQ    P F R L+D+ E   G    F+  ++  S+P + V WYKDG+P+  S  + 
Sbjct: 8976 TVQEQKLP-PSFSRQLRDVQETV-GLPVVFDCAISG-SEP-ISVSWYKDGKPLKDSPNVQ 9031

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            + F     +LNI       AG Y+  A N +G A S+A +
Sbjct: 9032 TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    P F   ++D +    G    F+  +   G   + V W KDG+P++ S  + T 
Sbjct: 8977 VQEQKLPPSFSRQLRD-VQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNVQTS 9033

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
            F      L I       AG Y+C A N IG A++SA L +   K+
Sbjct: 9034 FLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN 9078



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/131 (23%), Positives = 60/131 (45%), Gaps = 2/131 (1%)

Query: 449   ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVREGEP 507
             +L++T +           ARN  G +  +    V E KEQ++ PK +     + ++ G+ 
Sbjct: 19784 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP-EQITIKAGKK 19842

Query: 508   VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
             + + A   G P P   W+K    ++ +  L +H    +S L I      D+ +Y  TA+N
Sbjct: 19843 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN 19902

Query: 568   VAGSTATRARL 578
              +G+   + ++
Sbjct: 19903 SSGTDTQKIKV 19913



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 25/94 (26%), Positives = 41/94 (43%)

Query: 4410  PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
             PP F        V   E  + +V F G P P + W+++N P+K +      +    S+L 
Sbjct: 23074 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 23133

Query: 4470  IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
             I+    ED   +     N  G A  + N++V +K
Sbjct: 23134 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 23167



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 1/118 (0%)

Query: 378  ETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            E +  ++ISE +A+   F    ++  + EG    F C+++G P P++ W+ + ++I+   
Sbjct: 1276 EEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE 1335

Query: 437  NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             +++   + G  +L I  V   D G+ T  A N  G      +L V     + AP ++
Sbjct: 1336 RYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1393



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 2/100 (2%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096
            V + + P F+  +  +  ++ G+SA    +++    + +T  W+ N K+++ +N ++ Y 
Sbjct: 4658 VTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVT--WFKNNKELSESNTVRMYF 4715

Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                  LDI  V+ EDSG Y+  A N  G    S  + ++
Sbjct: 4716 VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK 4755



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G++    C ++ S  P +++ WF NNK L      +     S   LDIT    EDSG Y+
Sbjct: 4679 GESARLHCKLKGS--PVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYS 4736

Query: 2848 CKATNSKGSATTS 2860
            C+A N  GS + S
Sbjct: 4737 CEAVNDVGSDSCS 4749



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K    FV+ L     + +G    L C++   G P +++ WF N R +   S+ +  +   
Sbjct: 5223 KEPATFVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFVES 5280

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               L +      D+GEY   A N  GS H S+IV V E
Sbjct: 5281 TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKE 5318



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 2/100 (2%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            SV   P+FV + ++ +   +G+ +  ECK+    +  +KV WF+N   +    ++     
Sbjct: 7286 SVKEPPKFVKKLEASKVAKQGESIQLECKISGSPE--IKVSWFRNDSELHESWKYNMSFI 7343

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS 1538
                 L I +  AEDSG Y C A N VG    S  LT ++
Sbjct: 7344 NSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 7383



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 3/96 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++PL +   V  G+   L+C+++  G P +R+ W+     +     +K  +     +
Sbjct: 7947 PYFIEPLEHVEAVI-GEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVAS 8003

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            L I     +D GEY+ +A N +G+  +SA++ + ER
Sbjct: 8004 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKER 8039



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 37/156 (23%), Positives = 63/156 (40%), Gaps = 5/156 (3%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G   + I W+     + ++   +  +   +  L I     +D G YSC+A N  G    S
Sbjct: 7972 GTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASS 8031

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              L  V K +   P F   ++++     G    FEC  +   +P +++ WY +G  ++  
Sbjct: 8032 AVL--VIKERKLPPFFARKLKDVHETL-GFPVAFECR-INGSEP-LQVSWYKDGVLLKDD 8086

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ++T        L I  T     G+Y C A N  G
Sbjct: 8087 ANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLG 8122



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 26/85 (30%), Positives = 48/85 (56%), Gaps = 3/85 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F  +P  IE  ++G  VH EC+L+     +  V W+K+ + +  G +++ + +    +
Sbjct: 8326 PIFRKKPHPIET-LKGADVHLECELQGTPPFH--VSWYKDKRELRSGKKYKIMSENFLTS 8382

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTD 1528
            + I+++ A D G Y C+A N VG+D
Sbjct: 8383 IHILNVDAADIGEYQCKATNDVGSD 8407



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 3/104 (2%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            + K+PP F  Q  +  ++ E E  +  C +   G   ++++W   G+ +   +R +  + 
Sbjct: 9268 EPKKPPVF-DQHLTPVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFA 9324

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             G   +    V   DSG+Y+C+A+N+ G D TK+ +    KP +
Sbjct: 9325 SGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV 9368



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 19/152 (12%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF  HL  +   EG+ +   C+V+ S +P ++I+W    + +    R   +       L+
Sbjct: 9274 VFDQHLTPVTVSEGEYVQLSCHVQGS-EP-IRIQWLKAGREIKPSDRCSFSFASGTAVLE 9331

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL-------------RCTGDKNIYFDTQHPQGK 2881
            +    + DSG Y CKA+N  GS TT   +             +   D  ++F    PQ  
Sbjct: 9332 LRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFF-VSEPQ-- 9388

Query: 2882 AGLEAVEQAEEARLAKGRRPSVPDTEYPKPEW 2913
              +  VE+     +AK     +P+ ++ K +W
Sbjct: 9389 -SIRVVEKTTATFIAKVGGDPIPNVKWTKGKW 9419



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 86/385 (22%), Positives = 153/385 (39%), Gaps = 39/385 (10%)

Query: 1558  LEDRSKYH------RTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKV 1611
             LED   Y+      RTD   +V   A    +  +N+EI EG++A F   +  +S  +  V
Sbjct: 13453 LEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEF---VCSISKESFPV 13509

Query: 1612  EWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA---VTSGIAI 1668
             +W  ++K L+SG ++    +     L +     +D GTY      A   A   V   + I
Sbjct: 13510 QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRI 13569

Query: 1669  VHSKKSIYLESQHEGALP-RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKD-IRVAENQ 1726
             V   K   ++ Q E      +N     +K+ R+   +E I  +  + +  KD +     +
Sbjct: 13570 VVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRN---EEAIFDSSKYIILQKDLVYTLRIR 13626

Query: 1727  AAHFEARL-IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPEDSGTYT 1784
              AH + +    V     R E +++     A+N +    D   V  L       + S T+ 
Sbjct: 13627 DAHLDDQANYNVSLTNHRGENVKS-----AANLIVEEEDLRIVEPLKDIETMEKKSVTFW 13681

Query: 1785  CRAINELGEAV----TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY-----QRRED 1835
             C+ +N L   +        +   ++ S +++        K     D   Y     Q +  
Sbjct: 13682 CK-VNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSV 13740

Query: 1836  VEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
              E+ + +AP  F+  L   T ++E   A + C++         V+WY NG+ ++ G +Y+
Sbjct: 13741 AELLIIEAPTEFVEHLEDQT-VTEFDDAVFSCQLSR---EKANVKWYRNGREIKEGKKYK 13796

Query: 1895  TSNDFGFAALDILTVYGEDSGEYTC 1919
                D     L I     +D  EY C
Sbjct: 13797 FEKDGSIHRLIIKDCRLDDECEYAC 13821



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQKPRNSKL---QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             V PP++    +   +   + G   +    ++G P P ++W K+G  +    + EII+T N
Sbjct: 26711 VEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN 26770

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
             HT L V++  + D+G Y L  +N  G
Sbjct: 26771 HTLLTVKDCIRRDTGQYVLTLKNVAG 26796



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            +PP      KN    +G +   E  + G P+P V+W R+   +     + + +  Q+G  
Sbjct: 941  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF--QSGIA 998

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             L+I++    D G +TC+A N+ G    S Y+
Sbjct: 999  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL 1030



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 8/116 (6%)

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
            + LE+    K    I ES  ++  F  R K+   ++EG  V F CK+        K+ W+
Sbjct: 1269 ELLEEDGEEKMAVDISESEAVESGFDLRIKNYR-ILEGMGVTFHCKMSGYPLP--KIAWY 1325

Query: 1482 KNGQPVTIGHRFRPIHDF---GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            K+G+ +  G R++   DF   G  +L I  ++ ED GIYT  A N+ G    S +L
Sbjct: 1326 KDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL 1379



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 12/173 (6%)

Query: 3050 FTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLE 3109
            FT   +D+V   +  +A +E     T +  + ++W+ +G  +    + R      +  L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3110 ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHF 3169
            IL   T+D+  YSC         + +VK       +G    F   +Q+IE + +  S   
Sbjct: 2233 ILTIDTSDAEDYSCVLVE-----DENVKTTAKLIVEGAVVEFVKELQDIE-VPESYSGEL 2286

Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            EC V P    +++ +WYHN   ++ + +    S  G   L +      D GEY
Sbjct: 2287 ECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2336



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 2/110 (1%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP  T  L+NV+         + ++       ++V W+ + K + +  R+      G  +
Sbjct: 5039 APFFTKPLRNVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALP 1686
            L+I+     D+G +TCRA N++G   +SG  IV    S   +   +  LP
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLP 5146



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L N+          +C +  S    +++ WF + K + +  RY+        SL+I
Sbjct: 5042 FTKPLRNVDSVVNGTCRLDCKIAGSLP--MRVSWFKDGKEIAASDRYRIAFVEGTASLEI 5099

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                  D+G +TC+ATNS GS  +SG+L
Sbjct: 5100 IRVDMNDAGNFTCRATNSVGSKDSSGAL 5127



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            VQ+ P F T   S D L  G  V L++  +  T   L I WFK    L +G     T + 
Sbjct: 5129 VQEPPSFVTKPGSKDVL-PGSAVCLKSTFQGSTP--LTIRWFKGNKELVSGGSCYITKEA 5185

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIG 2754
               +L +  ++  DSG YTCK +N+ G    +A++ +++    + E L P  L + G
Sbjct: 5186 LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFV-EKLEPSQLLKKG 5241



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/102 (23%), Positives = 53/102 (51%), Gaps = 4/102 (3%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V ++P F++    IE ++  +V L   +   G     + WF +   +++G +++   +
Sbjct: 5314 VIVKESPYFTKEFKPIEVLKEYDVMLLAEV--AGTPPFEITWFKDNTILRSGRKYKTFIQ 5371

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
               V+L +L     D+G Y C+ TN++G ++  C+ RV  ++
Sbjct: 5372 DHLVSLQILKFVAADAGEYQCRVTNEVGSSI--CSARVTLRE 5411



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 5/90 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   L  ++++K G     EC V   +   ++I WF + Q+I A  +Y+ +       
Sbjct: 5602 PSFTKKLKKMDSIK-GSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            L+I      DSGTY C ATNK G   N C+
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGH--NQCS 5686



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 2/71 (2%)

Query: 4110 PPVFVSLPDAVTV-EEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHF 4167
            PP F+  P  V V   G+   F C++TG PK RV W L+GN I    ++ +++ DG+  F
Sbjct: 5787 PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATF 5846

Query: 4168 DIPKTRQYDTG 4178
             I   R  ++G
Sbjct: 5847 QISGARVENSG 5857



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 76/358 (21%), Positives = 137/358 (38%), Gaps = 44/358 (12%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    +V W +  R +    R   +F      L + ++ +  +G YTC   N  GQA+ +
Sbjct: 6845 GTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCT 6904

Query: 997  ANL---------------TIVTKKDIIAESQHPGGLE-KIQYLEDASRYSKRTEEEVKIT 1040
              L               ++   K II ES + G L   + + +D    +   +  +  T
Sbjct: 6905 TRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTT 6964

Query: 1041 QKPRFLGPLKGTNKIVEGQSAHF--EARVEPQSDLTMTVE-WYFNGKQITSANRIQTYHD 1097
            +K   L  L  T +     S     EA  +    L  T+E  YF    +T    ++    
Sbjct: 6965 EKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYF----VTELEPLEA--- 7017

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
                  D  S++ + +G   +      G+ +L    T E R+   T+++   ++ K    
Sbjct: 7018 ---AVGDSVSLQCQVAGTPEITVSWYKGDTKLRP--TPEYRTYF-TNNVATLVFNKVNIN 7071

Query: 1158 EESKFVEPMYQIEEISKSKPVF-VQPLSNPPPVSE---------GKNIHLECRLEPMGDP 1207
            +  ++          + SK VF +Q    PP  +          G  + L CRL   G  
Sbjct: 7072 DSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLN--GSA 7129

Query: 1208 TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             ++V W+ +G  +      +T +      L I+    + +G+Y+  A N LG+A +SA
Sbjct: 7130 PIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSA 7187



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            ++ ++ P F   L  +E   G +V L+C  Q  G   + V W+     ++    +R  + 
Sbjct: 7000 VSTLEPPYFVTELEPLEAAVGDSVSLQC--QVAGTPEITVSWYKGDTKLRPTPEYRTYFT 7057

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +   L    V   DSG YTC+A N +G A +    R+
Sbjct: 7058 NNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRI 7095



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 4/110 (3%)

Query: 1307 VMQAPQFSRALHNIETVEGTN-VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
            V + P+F + L     V+       EC++   G   ++V W+ +   I+   +FR ++  
Sbjct: 8228 VQEPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVD 8285

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
                L++ ++  EDSG YTC+A N  G A +S +L+V  +  +  +  HP
Sbjct: 8286 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV-KEPPIFRKKPHP 8334



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P FT+ L+   E  EG     E RV   G   +   WY N +E++  S    T     + 
Sbjct: 9176 PSFTKRLSETVEETEGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 9233

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
            L +     NDAGLY CK  N AG
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAG 9256



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 36/160 (22%), Positives = 63/160 (39%), Gaps = 4/160 (2%)

Query: 3498 YNNYGEAVTTASMKVQGKRNIILESQLPKGME--GTIDKIAALEGYSGTVDTLTPEAESG 3555
            Y N  E   T++ ++  K N ++      GM   G      + +  S    +     E  
Sbjct: 9211 YKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPK 9270

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
             PP F    + + +SE       C +       +R++W   G+ +    R       G  
Sbjct: 9271 KPPVFDQHLTPVTVSEGEYVQLSCHV--QGSEPIRIQWLKAGREIKPSDRCSFSFASGTA 9328

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI 3655
            +LE+  V + D+G Y CKA+N  G  T   K+ +K +  +
Sbjct: 9329 VLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV 9368



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 57/232 (24%), Positives = 93/232 (40%), Gaps = 31/232 (13%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            ++ I ++EPK  PP F   L   T V EG+     C V+   +P +RI++   G+ ++ +
Sbjct: 9261 TSSIVIKEPK-KPPVFDQHLTPVT-VSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPS 9316

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPE 2348
             R   +F  G   L+++     D+G+Y  KA N  G  T+   +T+  K           
Sbjct: 9317 DRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDK----------- 9365

Query: 2349 GLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTL 2408
                        P   P   +     R  F    Q+I  + E  TA F  ++   GDP  
Sbjct: 9366 ------------PAVAPATKKAAVDGRLFFVSEPQSI-RVVEKTTATFIAKV--GGDPIP 9410

Query: 2409 KVEWFRNE-KLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             V+W + + + +    R+          + I      D G+Y C A N  GE
Sbjct: 9411 NVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGE 9462



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V EG++V   C ++      ++++W K G+ +    R       G   L++ D+   DSG
Sbjct: 9284 VSEGEYVQLSCHVQG--SEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSG 9341

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             Y C+A N+ G+D    ++T +    +  +T+  A
Sbjct: 9342 DYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAA 9376



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 42/196 (21%), Positives = 85/196 (43%), Gaps = 7/196 (3%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
             ET E ++ SE    P  + +    D+T+  ++    +       ++T ++ + Q +    
Sbjct: 21881 ETTEPVKASEAPSPPDSLNIM---DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 21937

Query: 438   HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER- 496
                +    G   + + N+T  +      +A N +G +A +    VI KEQ + P+   R 
Sbjct: 21938 WTHITTVKGLECV-VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRG 21996

Query: 497   -FSTLNV-REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
              +  L + + G+ + +    +G P P +TW+K    +     +   T   ++ L+I    
Sbjct: 21997 IYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECV 22056

Query: 555   ASDAAWYQCTAQNVAG 570
              SD+  Y  TA+N+ G
Sbjct: 22057 RSDSGPYPLTARNIVG 22072



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 23/83 (27%), Positives = 37/83 (44%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P +  P     +  G+ ++    ++G+P P + W K  + +K +    +  TA    L I
Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 25298

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVT 4705
              E   +D G Y   A NSAG  T
Sbjct: 25299 KEGNKDDFGKYTVTATNSAGTAT 25321



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 2/82 (2%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V  G    F C ++    P +R  WF  GR      +    +     +L+I      D
Sbjct: 4392 LEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVD 4449

Query: 3765 AGEYTCRATNKWGSATTTAKIT 3786
             GEYTC+A+N++GS + TA +T
Sbjct: 4450 CGEYTCKASNEYGSVSCTATLT 4471



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 35/140 (25%), Positives = 59/140 (42%), Gaps = 7/140 (5%)

Query: 1790 ELGEAVTSSTLFVQSKASLQLESQ--HESALQKIQQLEDSSRYQRREDVEVAVNQAPRFI 1847
            EL E+ T    FV S+A L +      +S     + + D          E+ + + P FI
Sbjct: 4704 ELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSC--STEIVIKEPPSFI 4761

Query: 1848 TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL 1907
              L  P  +  G +A  +C +     P   + W+ + K ++S  +YR  +      L+I 
Sbjct: 4762 KTLE-PADIVRGTNALLQCEVSG-TGP-FEISWFKDKKQIRSSKKYRLFSQKSLVCLEIF 4818

Query: 1908 TVYGEDSGEYTCKAINNLGQ 1927
            +    D GEY C   N +G+
Sbjct: 4819 SFNSADVGEYECVVANEVGK 4838



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP FI  ++    +V G +A  +   V    P  ++ WF + K++    +YR F    +
Sbjct: 4756 EPPSFIKTLEPAD-IVRGTNALLQCE-VSGTGP-FEISWFKDKKQIRSSKKYRLFSQKSL 4812

Query: 3340 VILDILYCYEENSGEYECVATNKLGR 3365
            V L+I      + GEYECV  N++G+
Sbjct: 4813 VCLEIFSFNSADVGEYECVVANEVGK 4838



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 2/107 (1%)

Query: 759  QESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
            Q S+ E   + P  I    +L ++  G  A  E   T    P ++ +WYKDGRP+ AS +
Sbjct: 4932 QTSVGELIVKEPAKIIERAELIQVTAGDPATLE--YTVAGTPELKPKWYKDGRPLVASKK 4989

Query: 819  ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
                F      L        D+G YT    N++G +    +  V  R
Sbjct: 4990 YRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR 5036



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 2/81 (2%)

Query: 2111 FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALD 2170
            F+  L   + LK+GD     C+V     P + I WF N ++I+   ++R +       L 
Sbjct: 5228 FVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFVESTAVLR 5285

Query: 2171 ILYTYAEDSGTYMCKATNKLG 2191
            +     EDSG YMC+A N+ G
Sbjct: 5286 LTDVGIEDSGEYMCEAQNEAG 5306



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P  ++ WF +   L  G +Y+TF    +V L IL     ++GEY+C  TN++G     A 
Sbjct: 5347 PPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSAR 5406

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQ-TLEDSM 3404
            +      + I   +    + GG    Q TL+ S+
Sbjct: 5407 VTLREPPSFIKKIESTSSLRGGTAAFQATLKGSL 5440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 32/115 (27%), Positives = 49/115 (42%), Gaps = 3/115 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGK-IHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V  PPQFI     V  +  G+   FE +I   G P +++ W  +G  I A  +    F  
Sbjct: 5784 VKEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFID 5841

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQY 746
            G  +  +    +++SG Y C A +  G A     L V    T  R  +  E ++Y
Sbjct: 5842 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKY 5896



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 10/130 (7%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP+F+ +      L   ++T FECQ+   G P ++V W+ +G  +    +    +  G
Sbjct: 5785 KEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFIDG 5842

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIE--KI 4087
                       E+SG Y+C A N  G       +K    P  +      + +K +E  K 
Sbjct: 5843 LATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFI------RELKPVEVVKY 5896

Query: 4088 REMEASWQVT 4097
             ++E   +VT
Sbjct: 5897 SDVELECEVT 5906



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 3/109 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F + L+    V  G +IH+EC++   G   +  +WF +G+ ++  ++++       V+
Sbjct: 6164 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAI 1285
            L++ +    DT  YT +  N  G    S I+ V E    +     +QAI
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAI 6269



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G +IH EC V  S    +  +WF + K + +  +Y+       VSL++ +   ED+  YT
Sbjct: 6178 GSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYT 6235

Query: 2848 CKATNSKGSATTSGSL 2863
            CK +N  G    SG L
Sbjct: 6236 CKVSNVAGDDACSGIL 6251



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/239 (24%), Positives = 101/239 (42%), Gaps = 40/239 (16%)

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            +P  +    G   +  G++   E +V    +L+  VEWY +GK +TS+ +    H F + 
Sbjct: 6629 EPAVIVEKAGPMTVTVGETCTLECKVAGTPELS--VEWYKDGKLLTSSQK----HKFSFY 6682

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161
               I+S+R     + +V       E Q + + T + ++++  SS        T  ++ S 
Sbjct: 6683 N-KISSLR-----ILSV-------ERQDAGTYTFQVQNNVGKSSC-------TAVVDVSD 6722

Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221
               P           P F + L N   V  G +  LEC++   G   + V WFH    + 
Sbjct: 6723 RAVP-----------PSFTRRLKNTGGVL-GASCILECKVA--GSSPISVAWFHEKTKIV 6768

Query: 1222 VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280
             G++++T +      L +    S+D G YT  A N  GS    A++ V E    V + +
Sbjct: 6769 SGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 6827



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            + PP F+  L     V  G+ A  +C+V+    P +RI +Y     L+SA  + + F   
Sbjct: 7944 LEPPYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNN 8000

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              SL I      D GEYS KA N++G   S+  + +
Sbjct: 8001 VASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI 8036



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 61/231 (26%), Positives = 91/231 (39%), Gaps = 30/231 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P+F Q LT P  + EG++      V   G   +R +W   G E+K   R   +   G   
Sbjct: 9273 PVFDQHLT-PVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFASGTAV 9329

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L++  V   D+G Y+CKA N AG                       +S   I+ K A   
Sbjct: 9330 LELRDVAKADSGDYVCKASNVAGSDTT-------------------KSKVTIKDKPAVAP 9370

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFK-NGVTLT 2686
               +  VD  +     F +  +S  ++VE       A+V     PN+K  W K     L 
Sbjct: 9371 ATKKAAVDGRL----FFVSEPQSI-RVVEKTTATFIAKVGGDPIPNVK--WTKGKWRQLN 9423

Query: 2687 TGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             G R+          L I      DSG+Y C A N  GE  S  ++++++R
Sbjct: 9424 QGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 9474



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 4623  PEI---IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
             PEI   ++ L    V  G  IE    + GKP P + W K D ++K  K   +     + T
Sbjct: 14615 PEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 14674

Query: 4680  LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             + I ++   D G Y   A N  GR T   ++ V
Sbjct: 14675 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 14707



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 25/69 (36%), Positives = 37/69 (53%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L+ G   + +  +SG P P + W K+G+ L  + K EI      T L  +++ + DSG Y
Sbjct: 22400 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAY 22459

Query: 337   TLLAENPNG 345
             TL A NP G
Sbjct: 22460 TLTATNPGG 22468



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 82/394 (20%), Positives = 149/394 (37%), Gaps = 41/394 (10%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             R  V   G P P +KW + +  I+++    + +  T   L++  V   DS  +    EN 
Sbjct: 23888 RLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTS--LVLDNVNRYDSGKYTLTLENS 23945

Query: 4489  GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
              GT      + V +          PP        VN+   ++ +    +T   P+    L
Sbjct: 23946 SGTKSAFVTVRVLDTPS-------PP--------VNLKVTEITKDSVSITWEPPL----L 23986

Query: 4549  KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV--VSLP 4606
               G K++  I  K      +Y  ++   + ++S K + +    +   R  AE    + LP
Sbjct: 23987 DGGSKIKNYIVEKREATRKSYAAVVTNCH-KNSWKIDQLQEGCSYYFRVTAENEYGIGLP 24045

Query: 4607  ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
             A    P    K A  P    +   D +     ++ ++          +Q+    +     
Sbjct: 24046 AQTADP---IKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE 24102

Query: 4667  KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-------VTVAAKLKVTQPDQAD 4719
             K+ + +R      + I+     +E  ++ VA N  GR       V + AK  V +PD   
Sbjct: 24103 KWSECARVKSLQAV-ITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK- 24160

Query: 4720  NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
               PA +      V  GQ  + +  I+ + KPTI W ++G  + +T    +    +   L 
Sbjct: 24161 --PAFSSYS---VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLS 24215

Query: 4780  IGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             I  T+++D G +        GQ   S ++V   K
Sbjct: 24216 IKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 24249



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 35/132 (26%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 452   ITNVTLSDSGVVTCVARNKSGETAFQCRLN--VIEKEQVVAP--KF-VERFSTLNVREGE 506
             +T ++  D      +ARN  G  +   + +  ++ +++ V P  +F  E F  L ++ GE
Sbjct: 28842 VTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGE 28901

Query: 507   PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
              + + A   G P PR+TW KDGV I     + I    G+++L +  A       Y   A+
Sbjct: 28902 SLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAK 28961

Query: 567   NVAGSTATRARL 578
             N +GS     ++
Sbjct: 28962 NASGSAKAEIKV 28973



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 6/131 (4%)

Query: 734  IERTSQHPETLQYI-QQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEA 792
            I++ +      +Y+ + L D  K      +       P   R ++ L E+  G  A F  
Sbjct: 4346 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPL-EVALGHLAKFTC 4404

Query: 793  QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKL 851
            ++   S P +R +W+K GR I  S +  SI +  Y+ SL I+  +  D G YT +A N+ 
Sbjct: 4405 EIQ--SAPNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4461

Query: 852  GEAISTASIRV 862
            G    TA++ V
Sbjct: 4462 GSVSCTATLTV 4472



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)

Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ 1093
            + E+ I  KP F+  L+     +  +  H E +V+   D  +TV W  +G+++      +
Sbjct: 4562 QAELIIIDKPHFIKELEPVQSAIN-KKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYK 4618

Query: 1094 TYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
               +     L+I   + +DSG Y   A N AG +  SA++TV
Sbjct: 4619 ICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 4660



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 48/259 (18%), Positives = 104/259 (40%), Gaps = 10/259 (3%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            V+W++    L     Y + + ++   + + + ++   D G Y CTA N+ G + CS  + 
Sbjct: 4602 VTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLK--DSGTYVCTASNEAGSSSCSATVT 4659

Query: 163  P-EGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF 221
              E                  S  +  K  G+        +  ++++ +N     +   +
Sbjct: 4660 VREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESN-----TVRMY 4714

Query: 222  KVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGA 281
             V++     + +V   +S +      +DV  S      +    PP   +    + +  G 
Sbjct: 4715 FVNSEAILDITDVKVEDSGSYSCEAVNDVG-SDSCSTEIVIKEPPSFIKTLEPADIVRGT 4773

Query: 282  DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAE 341
            +A  Q ++SG     ++WFK+ +++ +S K+ + +  +   L + +   +D G Y  +  
Sbjct: 4774 NALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVA 4833

Query: 342  NPNG-CIVTSGYLAVESPT 359
            N  G C   + +L  E PT
Sbjct: 4834 NEVGKCGCMATHLLKEPPT 4852



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 2/102 (1%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P FT    ++    N +   +C++       MRV WF +GK +    R +     G   L
Sbjct: 5040 PFFTKPLRNVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 5097

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            EI  V   DAG +TC+ATN  G    S  L V+     + +P
Sbjct: 5098 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKP 5139



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 21/76 (27%), Positives = 39/76 (51%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ WFK+   +  G +++       V+L I+  +A D+G Y CR  N VG+   S R+T 
Sbjct: 5350 EITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTL 5409

Query: 1537 RSTTDIVRSTQNEAGL 1552
            R     ++  ++ + L
Sbjct: 5410 REPPSFIKKIESTSSL 5425



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + P+F+        +  GQS  FE ++     +   V WY +G +IT+  +       
Sbjct: 5784 VKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIR--VSWYLDGNEITAIQKHGISFID 5841

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            G     I+  R E+SG Y   ARN AG A  S  + V+
Sbjct: 5842 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 5879



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 2/103 (1%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F+R L N   V G +  LEC++   G   + V WF     I +G +++  +  +   L
Sbjct: 6727 PSFTRRLKNTGGVLGASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTL 6784

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQ 1413
             L S+   D G YTC A N  G       L V      + E +
Sbjct: 6785 QLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 6827



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K+ PVF Q  S P    +G ++ L+C +   G P   V W  + + V    +FK      
Sbjct: 7382 KAPPVFTQKPS-PVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHF 7438

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
              +L I++  ++D GEY  +A N +GS   S  V+  E
Sbjct: 7439 DTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE 7476



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            + +  E+  PP F  ++KD +    G PV F+CR+   G   +++ W+ +G      + +
Sbjct: 8033 VLVIKERKLPPFFARKLKD-VHETLGFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANL 8089

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
             T        L I        G+Y C A+N  G+A+++AK+  S
Sbjct: 8090 QTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILS 8133



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 3262 ELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321
            E  +  G+   + S    EPP F  +   +  L +G   H E  L     P   V W+ +
Sbjct: 8306 EAHNAAGSASSSTSLKVKEPPIFRKKPHPIETL-KGADVHLECELQGT--PPFHVSWYKD 8362

Query: 3322 GKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDS 3367
             ++L  G +Y+   +  +  + IL     + GEY+C ATN +G D+
Sbjct: 8363 KRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDT 8408



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 27/105 (25%), Positives = 55/105 (52%), Gaps = 8/105 (7%)

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            T  V E  T+++ P+      +I+   G    LEC +   G   +  +WF +GK + + +
Sbjct: 8506 TLSVLEPATIVEKPE------SIKVTTGDTCTLECTV--AGTPELSTKWFKDGKELTSDN 8557

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +++ ++      L +++V P DSGVY+ +  N +G+   + +L+V
Sbjct: 8558 KYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV 8602



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 12/140 (8%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVD 3142
            EWF NG+ ++   R +T     +  L I   +  D G Y+C+  +    AE+ ++ E + 
Sbjct: 9703 EWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPI- 9761

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
                   +FT  IQNI  + + QSA FEC    V   D  + WY     +  S +    +
Sbjct: 9762 -------QFTKRIQNIV-VSEHQSATFEC---EVSFDDAIVTWYKGPTELTESQKYNFRN 9810

Query: 3203 DFGFVVLDIAYTQNHDSGEY 3222
            D     + I      D G Y
Sbjct: 9811 DGRCHYMTIHNVTPDDEGVY 9830



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 74/400 (18%), Positives = 148/400 (37%), Gaps = 24/400 (6%)

Query: 4367  QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHE 4426
             + ++ VV DKE   ++ +     +   ++  E VV     P   P    +     V E E
Sbjct: 15272 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD--PDCKPTIDLETHDIIVIEGE 15329

Query: 4427  QARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAE 4486
             +    V F   P+P + W+++   +K S    +      + L + +    D+ ++    E
Sbjct: 15330 KLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLE 15389

Query: 4487  NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
             N+ G+A  S N+ V         G+  P   + A ++  +S +L     +  G  PI ++
Sbjct: 15390 NKLGSATASINVKVI--------GLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPI-LH 15440

Query: 4547  WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
             ++   ++        ++  +   +  + +  P     +   A+N  G         +  P
Sbjct: 15441 YVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGE---YIELKNP 15497

Query: 4607  ATKDKPKPQTKAANAPPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
                  PK Q        E+  P  +   I  +    +   KI+G  +  +   KG++  K
Sbjct: 15498 VIAQDPK-QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIA--KGEERWK 15554

Query: 4665  PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
                   +      YT +  E   E +  ++  A N+AG    +     T+     + P +
Sbjct: 15555 RCNEHLVPILT--YTAKGLEEGKEYQ--FRVRAENAAGISEPSRATPPTKAVDPIDAPKV 15610

Query: 4725  TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGALIPE 4763
                  + V  G        I+    PTI W++ E  ++PE
Sbjct: 15611 ILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPE 15650



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 3/120 (2%)

Query: 4596  RCDAECVVSLPATKDKPKPQTKAANAPPEI---IEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
             R  AE +V L         + +    PP +   ++ ++  +V  G  + F   I G P+P
Sbjct: 18408 RVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVP 18467

Query: 4653  TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             T +W      IK  +++ +        L I      D G+Y+    N+AG  TVA  L V
Sbjct: 18468 TAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 18527



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 44/177 (24%), Positives = 74/177 (41%), Gaps = 12/177 (6%)

Query: 3346 YCYEENSGEYE---CVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKL--- 3397
            + Y E   EYE    +   K+ +D+         +E  I   + +L + +E  + K    
Sbjct: 1209 FVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLE 1268

Query: 3398 QTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWY 3457
            + LE+    +    + E +     F + + N   L EG    F  +++    P  K+ WY
Sbjct: 1269 ELLEEDGEEKMAVDISESEAVESGFDLRIKNYRIL-EGMGVTFHCKMSGYPLP--KIAWY 1325

Query: 3458 WNGKSLKAGSRFR-TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             +GK +K G R++  F   G   L I    PED G Y   A N  G A+ +  + V+
Sbjct: 1326 KDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 69   PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
            P PP   Q  +      G  A+F   + G P P +SW +++  L    K    ++ Q  +
Sbjct: 3236 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQ--E 3293

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
             +LL+ +  P D   YTC A+N YG A  S  +  E
Sbjct: 3294 YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 49/174 (28%), Positives = 76/174 (43%), Gaps = 16/174 (9%)

Query: 1773 KY-VNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQ 1831
            KY ++PE+   +  ++  +  +A T  T  V S A +  E Q ES     ++ E SS   
Sbjct: 4210 KYLISPEEVSYFNVQSRVKYLDA-TPVTKGVAS-AVVSDEKQDESLKPSEEKEESSSESG 4267

Query: 1832 RREDVEVAVNQAPRFITQLNGP--------TKLSEGQSAHYECRIEPYPDPNMRVEWYFN 1883
              E   V + +A     + +GP        T   EG   H    I    + N    WYF 
Sbjct: 4268 TEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVN----WYFE 4323

Query: 1884 GKVLQSGHRYRTSNDFGFAALDILTVYGED-SGEYTCKAINNLGQAVSSIRLNV 1936
             K++ S  +++   D     L I  V  ED  GEY C+A+N+ G+  +S +L V
Sbjct: 4324 NKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4377



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 3/93 (3%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            + P FI +++ V   +  +  H E ++   +D  + V W  +G+KLP G  Y+   +  I
Sbjct: 4569 DKPHFIKELEPVQSAIN-KKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYKICFEDKI 4625

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L+I     ++SG Y C A+N+ G  S  A +
Sbjct: 4626 ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATV 4658



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 21/68 (30%), Positives = 33/68 (48%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L+ +W KDGRP+ AS +    F      L   S  +HD+G YT    N +G ++  
Sbjct: 4969 GTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCE 5028

Query: 997  ANLTIVTK 1004
               T++ +
Sbjct: 5029 TTFTVLDR 5036



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 3/106 (2%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            +D+   P F   +++  S+V   T + +C++A  G   M+V WF +GK +   +R+   +
Sbjct: 5034 LDRDIAPFFTKPLRNVDSVVN-GTCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAF 5090

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
              G  ++    V   D+G + CRATN  G  ++   +     P  V
Sbjct: 5091 VEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFV 5136



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 3/101 (2%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F  PL+  + +V G +   + ++     L M V W+ +GK+I +++R +     G  +
Sbjct: 5040 PFFTKPLRNVDSVVNG-TCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
            L+I  V   D+G +T  A N+ G    S ++ V+   S  T
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVT 5137



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 3/83 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   L +++++  G     +C++       + + WF +G++I A  RYR     G  +
Sbjct: 5040 PFFTKPLRNVDSVVNGT-CRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L+I+     D+G + C+ATN +G
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVG 5119



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F   +K   SIK G F   E  +   G   + ++W KD + + AS +    F+     
Sbjct: 5602 PSFTKKLKKMDSIK-GSFIDLECIVA--GSHPISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I  +   D+G YTC A N  G    S +LT+
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV 5691



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L  +   +G  I  EC V  S    + I+WF +++ + +  +YK +   +   L+I
Sbjct: 5604 FTKKLKKMDSIKGSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDNTAFLEI 5661

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            +     DSG YTC ATN  G    SG L
Sbjct: 5662 SQLEGTDSGTYTCSATNKAGHNQCSGHL 5689



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 22/94 (23%), Positives = 46/94 (48%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   ++ +  ++ + +D + + +++G P   VTW KN + + +S K+ +    +   L 
Sbjct: 5881 PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLH 5940

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            +     SD+G Y  +  N  G    S  +A++ P
Sbjct: 5941 ITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEP 5974



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 2/99 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP FI  +++ T +      F++ +   G P + I WLK+ Q ++        F     +
Sbjct: 5974 PPSFIKKIENTTTVLKSSATFQSTV--AGSPPISITWLKDDQILDEDDNVYISFVDSVAT 6031

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            L + S++   SG YTC+A + +GV    A L V   A I
Sbjct: 6032 LQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQI 6070



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 41/154 (26%), Positives = 62/154 (40%), Gaps = 5/154 (3%)

Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA--PICTTSLKNVEIKEGQRA 1595
            S+  I+   + +AG    QV  +  K   T +VD V+ +A  P  T  LKN     G   
Sbjct: 6686 SSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVD-VSDRAVPPSFTRRLKNTGGVLGASC 6744

Query: 1596 HFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAI 1655
              E ++     + + V W+H    + SG+++  T +     L + S    D G YTC A 
Sbjct: 6745 ILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAA 6802

Query: 1656 NALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN 1689
            N  G      +  V    S   E +    LP  N
Sbjct: 6803 NVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKN 6836



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P+F   ++     K+G     E ++   G   ++V W ++   +  S +    F    
Sbjct: 7289 EPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSV 7346

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              LTI   +  D+G Y C A+N +G A+ S  LT+
Sbjct: 7347 ALLTINEASAEDSGDYICEAHNGVGDASCSTALTV 7381



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 2/85 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  G    LE  V     P L  +WFK+G  LT+  + K +F   +  L I ++   DS
Sbjct: 8523 KVTTGDTCTLECTVAGT--PELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDS 8580

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDR 2737
            G+Y+ +  N +G+   TAS+++ DR
Sbjct: 8581 GVYSFEVQNPVGKDSCTASLQVSDR 8605



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 42/199 (21%), Positives = 83/199 (41%), Gaps = 13/199 (6%)

Query: 365   DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
             +  ++Y+ + + + T  ++ I  + +  +F+   +D    E +   F   ++      V 
Sbjct: 12831 EDEAKYMFEAEDKHTSGKLII--EGIRLKFLTPLKDVTAKEKESAVFTVELS-HDNIRVK 12887

Query: 425   WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
             WF ND+++    +   + +E   H++   ++++ D+  +   A   S E     +L V+E
Sbjct: 12888 WFKNDQRLHTTRSVS-MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEA----KLTVLE 12942

Query: 485   KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
              +    P F  +       E + V+L         P + W KDG  I P+    I  DG 
Sbjct: 12943 GD----PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGK 12997

Query: 545   ASTLDIPRAKASDAAWYQC 563
                L + +A  SD   Y C
Sbjct: 12998 KRMLILKKALKSDIGQYTC 13016



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 10/246 (4%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             + ++   G+PLP +   R+  P+K +  F     +    + +++    D+  +   A N 
Sbjct: 27422 KVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANS 27481

Query: 4489  GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
              GT K   N+VV +  R G     PP+  +   ++   S  L     K  G   +  Y L
Sbjct: 27482 SGTTKAFINIVVLD--RPG-----PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL 27534

Query: 4549  KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG-EARCDAECV-VSLP 4606
                ++    +  ++        + +++    +  ++   A N  G     D+ CV V LP
Sbjct: 27535 LK-RETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLP 27593

Query: 4607  ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
              T   P       N   E I     + V+ G +      +  K   ++ W K +KL+  +
Sbjct: 27594 YTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRT 27653

Query: 4667  KYFQMS 4672
              +F+++
Sbjct: 27654 THFKVT 27659



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 4/97 (4%)

Query: 2642  PIFTTHLKSYDKLV--EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
             PI     + +D L+   G+ + ++A V+ R  P  ++ WFK+GV +     ++ T   G 
Sbjct: 28883 PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVP--RVTWFKDGVEIEKRMNMEITDVLGS 28940

Query: 2700  VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              +L +     D  G+YT +A N  G A +   +K++D
Sbjct: 28941 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 28977



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F+ +++S TV +   VR + RV     P   +++YR+G  + S   ++   +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDL 158

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             SL I   Y EDSG Y   A N  G   + A +
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 32/89 (35%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH-DFSYVSLD 2834
            F   + N    EG  + F C +  S  P  KI W+ + K +  G RY+         SL 
Sbjct: 1293 FDLRIKNYRILEGMGVTFHCKM--SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLR 1350

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I     ED GIYT  A+N KG+A  SG L
Sbjct: 1351 IPVVLPEDEGIYTAFASNIKGNAICSGKL 1379



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 78/382 (20%), Positives = 141/382 (36%), Gaps = 26/382 (6%)

Query: 3273 TPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR 3332
            T +   A PP F+++ + +T  V G++A F   +     P ++  W  +G  L     ++
Sbjct: 4469 TLTVTEAYPPTFLSRPKSLTTFV-GKAAKFICTVTGT--PVIETIWQKDGAALSPSPNWK 4525

Query: 3333 TFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392
                    IL++     ++ G Y C A+NK G D  +A L    K + I + +    ++ 
Sbjct: 4526 ISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELE---PVQS 4582

Query: 3393 GLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNL 3452
             + K   LE  +   +  +V   K    +   P  + +   E + A  E  L    D   
Sbjct: 4583 AINKKVHLECQVDEDRKVTVTWSKDGQKL--PPGKDYKICFEDKIATLEIPLAKLKDSGT 4640

Query: 3453 KVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTY---PEDSGEYLCRAYNNYGEAVTTAS 3509
             V    N     + S   T  +    + ++ P+Y   P +S    C+   +    VT   
Sbjct: 4641 YVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFK 4700

Query: 3510 MKVQGKRNIILESQLPKG---MEGTIDKIAALEGYSGTV------DTLTPEAESGNPPEF 3560
               +   +  +          ++ T  K+     YS         D+ + E     PP F
Sbjct: 4701 NNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSF 4760

Query: 3561 --TTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILE 3618
              T  P+D++   N  A  +C +         + WF + K + +  + +  +    V LE
Sbjct: 4761 IKTLEPADIVRGTN--ALLQCEV--SGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLE 4816

Query: 3619 IGGVYQRDAGLYTCKATNRHGE 3640
            I      D G Y C   N  G+
Sbjct: 4817 IFSFNSADVGEYECVVANEVGK 4838



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+     +  + V+LE QV+   D  + + W K+G  L  G   K  F+  + T
Sbjct: 4571 PHFIKELEPVQSAIN-KKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIAT 4627

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L I   +  DSG Y C A+N  G +  +A++ + +
Sbjct: 4628 LEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE 4662



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++   F + L+    +++G      C++   G P +K+ WF N++ I++SS+   +    
Sbjct: 5223 KEPATFVEKLEPSQLLKKGDATQLACKV--TGTPPIKITWFANDREIKESSKHRMSFVES 5280

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
               + ++ V  ED G YMC A N  G
Sbjct: 5281 TAVLRLTDVGIEDSGEYMCEAQNEAG 5306



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PVF +    +E LK  +    EC +     P   + W+ + +++R+  +Y+      + +
Sbjct: 6444 PVFSSFPPIVETLKNAE-VSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNFHTS 6500

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            + IL     D G Y CKA N++G     CT+K+
Sbjct: 6501 IHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL 6533



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 3/115 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP FT  +K+   V  G     +C+V   G   + + WFH      +G++  T       
Sbjct: 6726 PPSFTRRLKNTGGVL-GASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVC 6782

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
             L ++ + + D G YTC A N  GS    A +T       V E +  + + G+ +
Sbjct: 6783 TLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNV 6837



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 4/102 (3%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P F +   ++E + G ++     ++  G    +V+WF   + +  G     + E
Sbjct: 7755 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIR--GTPPFKVKWFKGSRELVPGESCNISLE 7812

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
                 L+L  V P +SG Y+C  TN  G A  SC   +  K+
Sbjct: 7813 DFVTELELFEVQPLESGDYSCLVTNDAGSA--SCTTHLFVKE 7852



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 3/98 (3%)

Query: 1707 ITQAPVFTMPMKDIRVA-ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + P F   ++  R+  +++   +E ++   G P+++V W ++   I+ S++       
Sbjct: 8228 VQEPPRFIKKLEPSRIVKQDEFTRYECKI--GGSPEIKVLWYKDETEIQESSKFRMSFVD 8285

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
                L M  ++ EDSG YTC A N  G A +S++L V+
Sbjct: 8286 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 8323



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 23/94 (24%), Positives = 49/94 (52%), Gaps = 2/94 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP+FI +++    + + +   +E ++     P++KV W+ +  ++    ++R      +
Sbjct: 8230 EPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDSV 8287

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
             +L++     E+SG+Y C A N  G  S+  +LK
Sbjct: 8288 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLK 8321



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 5/116 (4%)

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            +E+ S     SAQ  +I + P F   ++ ++V+   +A  + +L   G P++ V W +  
Sbjct: 8869 IENASGKDSCSAQI-LILEPPYFVKQLEPVKVSVGDSASLQCQL--AGTPEIGVSWYKGD 8925

Query: 1751 VPIEASNRLTTMHDFGYVA-LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
              +  +     MH    VA L    V+  DSG Y C+A N +GE   S+ L VQ +
Sbjct: 8926 TKLRPTTTYK-MHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 8980



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +    V+EG  V L   +   ++P +R++W   GR ++   R   ++  G   L
Sbjct: 9273 PVFDQHLTPVTVSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVL 9330

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            ++      D+G Y+CKA+N  G   T S V +  K
Sbjct: 9331 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDK 9365



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 48/232 (20%), Positives = 83/232 (35%), Gaps = 8/232 (3%)

Query: 4583  KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             +Y   A N AG  +C   C          P  Q +  N   + +     K   +G A   
Sbjct: 26585 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKIT 26644

Query: 4643  SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                +  + LP  +W K +       YF+++   ++        F  +  D       S G
Sbjct: 26645 GYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEF-RVFARNAADSVSEPSESTG 26703

Query: 4703  RVTVAAKLKVTQPDQADNLPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALI 4761
              + V  K  V  P    ++      RD++V + G+  +    I  +  P I W ++G  I
Sbjct: 26704 PIIV--KDDVEPPRVMMDVK----FRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 26757

Query: 4762  PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              E    ++I   N+ +L + +    DTG +       AG    +    V  K
Sbjct: 26758 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 26809



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 35/146 (23%), Positives = 65/146 (44%), Gaps = 7/146 (4%)

Query: 4568  TYTLLILEAYPQDSG-KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
             T T  I+    Q+S  ++   A N+ G     +E V  +        P     + P E  
Sbjct: 27750 TETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGP---VIDLPLEYT 27806

Query: 4627  EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
             E +K +    G +++    I GKP PT++WYK DK ++ +    +  T D  ++ I +A 
Sbjct: 27807 EVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDAD 27863

Query: 4687  PEDEGDYKCVAYNSAGRVTVAAKLKV 4712
               + G Y+    N+ G  +   ++++
Sbjct: 27864 RLNSGCYELKLRNAMGSASATIRVQI 27889



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 23/69 (33%), Positives = 36/69 (52%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G   + +  + G P PRVTWFK+G  +      EI      T+L VR+  +   G Y
Sbjct: 28897 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28956

Query: 337   TLLAENPNG 345
             T+ A+N +G
Sbjct: 28957 TVEAKNASG 28965



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 12/139 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-- 2164
            Q P F   L S+  L EG  A FE  +     P   + WF +GQ I           F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSD 60

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
            G   L I      +SG Y  KATN  G+A +T  L V        +T  PN +++++ + 
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------ETAPPNFVQRLQSMT 114

Query: 2225 A-QGHSTRIEVEEPKISPP 2242
              QG   R++V    I  P
Sbjct: 115  VRQGSQVRLQVRVTGIPTP 133



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 4/130 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P F   ++ + V +      + R+   G P   V++ R+G  I++S       +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L +    PEDSGTY+  A N +G A +++ L VQ +   ++ ++    +    Q+ +S
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--EVPAKKTKTIVSTAQISES 216

Query: 1828 SRYQRREDVE 1837
             + +  + +E
Sbjct: 217  RQTRIEKKIE 226



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 4/134 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+  L+S+T  +G ++  + R+   G PT  +++ ++G  I++S  F         S
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
           L +     +DSG Y+  A ++ G A + A L V  +   E  ++  +T+    Q+ +  +
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV--QGEEEVPAKKTKTIVSTAQISESRQ 218

Query: 756 YQHQESIEEQTSQR 769
            + ++ IE     R
Sbjct: 219 TRIEKKIEAHFDAR 232



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYVAL 1770
            F + +K+ R+ E     F  ++   G P  ++ W ++G  I+   R  +  + D G  +L
Sbjct: 1293 FDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQD-GRASL 1349

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
             +  V PED G YT  A N  G A+ S  L+V+  A L
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPL 1387



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            R+ P F + +     +  G++A   C+L   G P ++V WF+N K + +S+ +       
Sbjct: 4661 REPPSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVNS 4718

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
               + I+ V+ ED G Y C A N +G
Sbjct: 4719 EAILDITDVKVEDSGSYSCEAVNDVG 4744



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 26/120 (21%), Positives = 53/120 (44%), Gaps = 2/120 (1%)

Query: 1700 HSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            H +   ++ ++P FT   K I V +       A +   G P   + W ++   + +  + 
Sbjct: 5309 HCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEV--AGTPPFEITWFKDNTILRSGRKY 5366

Query: 1760 TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
             T      V+L +      D+G Y CR  NE+G ++ S+ + ++   S   + +  S+L+
Sbjct: 5367 KTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLR 5426



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 17/164 (10%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
            +IE +   PP F  E+K  ++V +   V  +C V   G P   + W  N R   + S+ +
Sbjct: 5873 SIELKVKEPPTFIRELKP-VEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRS-SKKY 5928

Query: 3746 TLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
            TL D      L I      D GEY C  +N+ GS + + ++        +          
Sbjct: 5929 TLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFI---------- 5978

Query: 3805 GEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV-EESEGV 3847
             +KI+       S A  +  +  +PP  IT +K   + +E + V
Sbjct: 5979 -KKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNV 6021



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/107 (28%), Positives = 54/107 (50%), Gaps = 6/107 (5%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR-TFCDFGFV 3478
            P F   L   + ++ G+++  E ++  +  P ++V W+ N   L A  ++R TF D    
Sbjct: 6350 PKFVKKLEASKIVKAGDSSRLECKIAGS--PEIRVVWFRNEHELPASDKYRMTFID-SVA 6406

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLP 3525
            +++++    EDSG+++C A N  G   T+ S KV  K   +  S  P
Sbjct: 6407 VIQMNNLSTEDSGDFICEAQNPAGS--TSCSTKVIVKEPPVFSSFPP 6451



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D+  PP F+ +++   +++       EC+++  G   + V WF +G  ++   +    + 
Sbjct: 7663 DRIVPPSFIRKLKDVNAILGASVV-LECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFS 7719

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
                 +N   + P D+G Y C A N+ G DE  AV+     P
Sbjct: 7720 ENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPP 7761



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  ++KD ++   G  V  +CRV   G   + + WF +G    +G +  +       
Sbjct: 7667 PPSFIRKLKD-VNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVC 7723

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             L++  +   D G YTC A N  GS   +A +T
Sbjct: 7724 TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLT 7756



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 79/381 (20%), Positives = 146/381 (38%), Gaps = 27/381 (7%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   P  + L+   S  F+C +     + +++ W  + + +  G   K         
Sbjct: 8138 PPFFDLKPVSVDLALGESGTFKCHV--TGTAPIKITWAKDNREIRPGGNYKMTLVENTAT 8195

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L +  V + DAG YTC A+N  G+ + S  L V+     I + + PS      E   + E
Sbjct: 8196 LTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPPRFIKKLE-PSRIVKQDE-FTRYE 8253

Query: 3677 ETLHKREEITI-----EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731
              +    EI +     E E     +F +   D++ V E   +H +  VE  GD T     
Sbjct: 8254 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLE---MH-NLSVEDSGDYTCEAHN 8309

Query: 3732 FHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAG-EYTCRATNKWGSATTTAK--ITCS 3788
                   +T  +V     F      I+ +   D   E   + T  +  +    K  +   
Sbjct: 8310 AAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSG 8369

Query: 3789 AKRDIVLESQLPQ----GMSGEKIKELERGRISDAPKEEPI----VSTPPKFITQIKSHT 3840
             K  I+ E+ L       +    I E +    +D   +  +    +  PP+F+ ++   +
Sbjct: 8370 KKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDIS 8429

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRN-GKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899
                + V+ +  +E  E   + + W+++ G+++         Y     +L    V   ++
Sbjct: 8430 TVVGKEVQLQTTIEGAE--PISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANA 8487

Query: 3900 GEYICRAVNDFGEDFTKATIS 3920
            G+Y C+  ND G     AT+S
Sbjct: 8488 GKYTCQIKNDAGMQECFATLS 8508



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L     +K+ +   +EC++     P + + W+ +  +I+   ++R +       
Sbjct: 8232 PRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDSVAV 8289

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L++     EDSG Y C+A N  G A ++ +LKV
Sbjct: 8290 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 8322



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/112 (24%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E    P F   + + +   EG     E R+   G   + V W K+   ++ +S     
Sbjct: 9169 IKERLIPPSFTKRLSETVEETEGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEIT 9226

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            F    + L ++   ++DAG YTC+  N  G A  ++++ I   K      QH
Sbjct: 9227 FKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH 9278



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPI-KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            P F K + +  E TEG+   LE  +       + V WY N   +Q     + T+    + 
Sbjct: 9176 PSFTKRLSETVEETEGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 9233

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +  A   D G Y CK +N  G A+ TSS+ +
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVI 9266



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 3825  IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
             I+  P +F+  ++  TV E +   F C++  +   K  ++WYRNG+ +  G +Y+   D 
Sbjct: 13745 IIEAPTEFVEHLEDQTVTEFDDAVFSCQLSRE---KANVKWYRNGREIKEGKKYKFEKDG 13801

Query: 3885  GFVSLDILYVYAEDSGEYIC 3904
                 L I     +D  EY C
Sbjct: 13802 SIHRLIIKDCRLDDECEYAC 13821



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/91 (27%), Positives = 43/91 (47%)

Query: 481   NVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH 540
             NV+ K+    P        + V EGE + +       P P ++W KDG  +  +  L + 
Sbjct: 15304 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 15363

Query: 541   TDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              D  ++ L++P++  +DA  Y  T +N  GS
Sbjct: 15364 NDHISAHLEVPKSVRADAGIYTITLENKLGS 15394



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)

Query: 4512  VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
             + PS  L     ++ +G+ ++++  V G    ++ W+K+G+ ++   R  + EE  T T+
Sbjct: 25237 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV-EETATSTV 25295

Query: 4572  L-ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
             L I E    D GKY   A NSAG A  +   +V
Sbjct: 25296 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 25328



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 4/110 (3%)

Query: 467   ARNKSG-ETAFQCRLNVIEKEQVVAPKF-VERFS--TLNVREGEPVVLNARAVGTPTPRI 522
             A N++G     +  L V+ KEQ+  P+  ++ F   T+ VR G  + ++    G P P++
Sbjct: 27376 AENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 27435

Query: 523   TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             T  +DGVP+               T+++  +  +DA  Y+ TA N +G+T
Sbjct: 27436 TLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTT 27485



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS--RFTSIFRFGYI 694
           P F  PL+SV  +EG    FE  I   G P  ++ W ++GQ I  S+       F  G  
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + ++   +SG Y+ +A + +G A + A L V
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 3/115 (2%)

Query: 1694 TSKYQRHSAQDE-VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVP 1752
            ++K+     Q E +I   P F   ++ ++ A N+  H E ++    D K+ V W ++G  
Sbjct: 4553 SNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDE--DRKVTVTWSKDGQK 4610

Query: 1753 IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            +          +     L +     +DSGTY C A NE G +  S+T+ V+   S
Sbjct: 4611 LPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS 4665



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 2/81 (2%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F   L   + L++G+      ++T T  P +K+ W+ N + +K  S+ R        +L 
Sbjct: 5228 FVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVESTAVLR 5285

Query: 3482 ISPTYPEDSGEYLCRAYNNYG 3502
            ++    EDSGEY+C A N  G
Sbjct: 5286 LTDVGIEDSGEYMCEAQNEAG 5306



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 2/99 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F         L  GQ    E Q+     P +++ W+ +G  +T   +   +F  
Sbjct: 5784 VKEPPQFIKKPSPVLVLRNGQSTTFECQITGT--PKIRVSWYLDGNEITAIQKHGISFID 5841

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            GL T  I+  R ++SG Y C+A N  G A  +  +K+++
Sbjct: 5842 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKE 5880



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 3/119 (2%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            +E+ V + P FI +L  P ++ +      EC +   P     V W  N + ++S  +Y  
Sbjct: 5874 IELKVKEPPTFIRELK-PVEVVKYSDVELECEVTGTPP--FEVTWLKNNREIRSSKKYTL 5930

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
            ++      L I      D+GEY C   N  G    S R+ ++   S I+  ++ + + K
Sbjct: 5931 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLK 5989



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 43/191 (22%), Positives = 72/191 (37%), Gaps = 11/191 (5%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP FT     + D   G   H E  +  +G   +  +WF +GK I  S + R V  
Sbjct: 6159 DQNIPPSFTKKLTKM-DKVLGSSIHMECKV--SGSLPISAQWFKDGKEISTSAKYRLVCH 6215

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               V LE+   +  D+  Y+C+ +N  G    S  L     +  + P F       + + 
Sbjct: 6216 ERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGIL-----TVKEPPSFLVKPGRQQAIP 6270

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            D   +  E   +    P  KI+W+ +   +    +     +     L++       +G+Y
Sbjct: 6271 D---STVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQY 6327

Query: 3223 VCRAYNKYGED 3233
             C   N  G D
Sbjct: 6328 TCHVTNDVGSD 6338



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 2/83 (2%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F + L+    ++ G ++  +C++   G P ++V WFRNE  +  S +   T       
Sbjct: 6350 PKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFIDSVAV 6407

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + ++++  ED G ++C A N  G
Sbjct: 6408 IQMNNLSTEDSGDFICEAQNPAG 6430



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   LK+   + G     E ++   G   + + W      I + +++ + F     +
Sbjct: 6726 PPSFTRRLKNTGGVLGASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCT 6783

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + SL+  D G YTC A +  G  E +AVL V
Sbjct: 6784 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV 6816



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 3/114 (2%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V   P F  +P  +   ++G  V  +C++        +V W K+ + V    +F+    
Sbjct: 7380 TVKAPPVFTQKPSPV-GALKGSDVILQCEISGTPP--FEVVWVKDRKQVRNSKKFKITSK 7436

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGL 1552
                +L I++L A D G Y C+A N VG+D  SC +  +     V+   + + L
Sbjct: 7437 HFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTL 7490



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 3/95 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++ L +   +  G ++ LECR+   G   + V WF +G  +  G + ++ +      
Sbjct: 7668 PSFIRKLKDVNAIL-GASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            L++     +DTG YT  A N  GS   SA++ V E
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE 7759



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L ++    G+    +C V+ +  P ++I W+  +  L S   YK     +  SL I
Sbjct: 7949 FIEPLEHVEAVIGEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 8006

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                  D G Y+CKA NS G+  +S  L
Sbjct: 8007 NKVDHSDVGEYSCKADNSVGAVASSAVL 8034



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 40/200 (20%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G++  F C +   G   +K+ W ++ + I        T      ++T+  V   D G Y 
Sbjct: 8153 GESGTFKCHV--TGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYT 8210

Query: 2451 CRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIF 2510
            C ASN+ G+                L  Q P   + I+KL         EP R  ++  F
Sbjct: 8211 CYASNIAGKDSCSA----------HLGVQEPP--RFIKKL---------EPSRIVKQDEF 8249

Query: 2511 TQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDI 2570
            T+               YE ++   G P ++  WY +  E++  S+FR +       L++
Sbjct: 8250 TR---------------YECKI--GGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 8292

Query: 2571 NSVVANDAGLYMCKAINRAG 2590
            +++   D+G Y C+A N AG
Sbjct: 8293 HNLSVEDSGDYTCEAHNAAG 8312



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/98 (25%), Positives = 50/98 (51%), Gaps = 2/98 (2%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + PRF+  L+ +  + + +   +E ++    ++   V WY +  +I  +++ +     
Sbjct: 8228 VQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIK--VLWYKDETEIQESSKFRMSFVD 8285

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                L++ ++  EDSG YT  A NAAG A  S S+ V+
Sbjct: 8286 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 8323



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/97 (26%), Positives = 50/97 (51%), Gaps = 3/97 (3%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHP-VHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P+F K ++ + + +       E  +     P ++V WY +   +Q+  +F+ ++  
Sbjct: 8228 VQEPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVD 8285

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L++     ED+G Y C+A NA G A +++S+KV
Sbjct: 8286 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 8322



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 2/91 (2%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PRF+ + +    V + +   +ECK+    +  +KV W+K+   +    +FR         
Sbjct: 8232 PRFIKKLEPSRIVKQDEFTRYECKIGGSPE--IKVLWYKDETEIQESSKFRMSFVDSVAV 8289

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L++ +L  EDSG YTC A N  G+   S  L
Sbjct: 8290 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSL 8320



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 32/128 (25%), Positives = 61/128 (47%), Gaps = 6/128 (4%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G+ P F     +  +   G+ A FEC V       + + W  + ++IR+G +Y+ ++   
Sbjct: 9076 GKNPPFFDIRLAPVDAVVGESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLEN 9133

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225
               L +L     DSG Y C A N++G+  ++CT ++     +I  +      E +   E 
Sbjct: 9134 SAHLTVLKVDKGDSGQYTCYAVNEVGK--DSCTAQLNIKERLIPPSFTKRLSETVE--ET 9189

Query: 2226 QGHSTRIE 2233
            +G+S ++E
Sbjct: 9190 EGNSFKLE 9197



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P +  HL+    L EGQ   +  Q      PN+K EWF+NG  L    R K+  +  +  
Sbjct: 9672 PAWERHLQDVT-LKEGQTCTMTCQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHK 9727

Query: 2702 LSINSLRNDDSGIYTCKATNL 2722
            L+I  +R +D G YTCK  +L
Sbjct: 9728 LTIADVRAEDQGQYTCKYEDL 9748



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 2/117 (1%)

Query: 377   RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
             RE E   E  E+ L P+ + + +   +  GK  R +  V G+P+P   W   + ++    
Sbjct: 19812 REAEGVYEAKEQLLPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS- 19869

Query: 437   NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
             +H  +     +  L+I +VT  DSG  +  A N SG    + ++ V++      P F
Sbjct: 19870 SHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 19926



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 22/61 (36%), Positives = 34/61 (55%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI WY   ++L  G + K   D    TL L++ +  D+ +YTC+A N  G A TS++
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325

Query: 3001 V 3001
            +
Sbjct: 3326 L 3326



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 2/95 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   +     +  G  A    +L+  G   ++V W K+ + +  S+ +  +F    
Sbjct: 4662 EPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSE 4719

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              L I  V V D+G Y+C A N +G  + S  + I
Sbjct: 4720 AILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI 4754



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 3557 PPEFT--TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP F     PS L+L    SA   C+L       ++V WF N K L   + V+       
Sbjct: 4663 PPSFVKKVDPSYLMLP-GESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVNSE 4719

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
             IL+I  V   D+G Y+C+A N  G  + S ++ +K     I   + P+    GT ++ +
Sbjct: 4720 AILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLE-PADIVRGTNALLQ 4778

Query: 3675 LE 3676
             E
Sbjct: 4779 CE 4780



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845
            K+GD     C V  +  P +KI WF N++ +   ++++ +   S   L +T    EDSG 
Sbjct: 5239 KKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGE 5296

Query: 2846 YTCKATNSKGS 2856
            Y C+A N  GS
Sbjct: 5297 YMCEAQNEAGS 5307



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 3/117 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP+F+ +      +  G++  FECQ+     P +R+ +Y +G  + +  +  I+F  G  
Sbjct: 5787 PPQFIKKPSPVLVLRNGQSTTFECQITGT--PKIRVSWYLDGNEITAIQKHGISFIDGLA 5844

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELE 2357
            +  I     E++G Y  +A N  G  + +I + V    + I E  +P  + K  ++E
Sbjct: 5845 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE-LKPVEVVKYSDVE 5900



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V +  Q      +++  E   + LEC +   G   ++V+W  +GK I     F  ++E
Sbjct: 6062 LLVQEPAQIVEKAKSVDVTEKDPMTLECVV--AGTPELKVKWLKDGKQIVPSRYFSMSFE 6119

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             +  +  + SV  +DSG YT +  N  G +     LRV+
Sbjct: 6120 NNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVL 6158



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 26/94 (27%), Positives = 50/94 (53%), Gaps = 3/94 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L   +K++ G S H E +V     L ++ +W+ +GK+I+++ + +       V+
Sbjct: 6164 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            L++ ++  ED+  YT    N AG+   S  +TV+
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 6254



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 5/101 (4%)

Query: 633  VYPPPQFIVPLKSVTAMEGG-KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V  PP+F+  L++   ++ G     E +I   G P +++ W +N   + AS ++   F  
Sbjct: 6346 VTEPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFID 6403

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATG--VAETKAVLHVTP 730
                + M +L+ +DSG++ C A +  G     TK ++   P
Sbjct: 6404 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 6444



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FV+ L     V  G +  LEC++   G P +RV WF N   +    +++  +      
Sbjct: 6350 PKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDSVAV 6407

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            + + + ++ D+G++   A N  GS   S  V V E
Sbjct: 6408 IQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE 6442



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 43/136 (31%), Positives = 59/136 (43%), Gaps = 6/136 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            E    P F   P  + +    SA FEC +       MR+ W  + K +  G    TI   
Sbjct: 7193 EPKKSPFFDIKPVSIDVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNY-TITCV 7249

Query: 3613 GFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES 3671
            G    L I  V + D+G YTC+ATN  G+   S +L VK     + + +     K G ES
Sbjct: 7250 GNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQG-ES 7308

Query: 3672 IQKLEETLHKREEITI 3687
            IQ LE  +    EI +
Sbjct: 7309 IQ-LECKISGSPEIKV 7323



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 3/99 (3%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474
            E  K+P F +   +I+ +  GE+A FE  +T      +++ W  + K ++ G  +   C 
Sbjct: 7193 EPKKSPFFDIKPVSIDVIA-GESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCV 7249

Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
                 L I      DSG+Y C+A N+ G+ + +A + V+
Sbjct: 7250 GNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 7288



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 2/97 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI ++K         V  ECRV       + + W+++G  + SG + ++ +     +
Sbjct: 7667 PPSFIRKLKDVNAILGASVVLECRVSGSAP--ISVGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L++  +   D+G Y C A N  G D   A ++ ++ P
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPP 7761



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 2/99 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +KD+      +   E R+   G   + V W ++G  I +  +  +        L
Sbjct: 7668 PSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 7725

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQ 1809
            N+  + P D+G YTC A N  G    S+ L VQ   S +
Sbjct: 7726 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFE 7764



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/102 (24%), Positives = 52/102 (50%), Gaps = 3/102 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++ + T G PV  +  ++  ++P + V WY +G+P++     +T++      L
Sbjct: 8984 PSFSRQLRDVQETVGLPVVFDCAISG-SEP-ISVSWYKDGKPLKDSPNVQTSFLDNTATL 9041

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSS-VKVDAKSGLYLD 2078
            +I        G Y C ATN +G A +++  +  + K+  + D
Sbjct: 9042 NIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFD 9083



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 4/128 (3%)

Query: 233   EVSFRESITKRYVGESDV-QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
             E SFR S  +   G SD  Q+S  +      V PP          +  G D +  V   G
Sbjct: 23043 EYSFRVS-AQNEKGISDPRQLSVPVIAK-DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG 23100

Query: 292   NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG-CIVTS 350
              P P VTW K+   L  + +    +T N++ L +++  + D GHY +   N  G  I T 
Sbjct: 23101 RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETL 23160

Query: 351   GYLAVESP 358
               + ++ P
Sbjct: 23161 NVIVLDKP 23168



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             GQ + +E  +  R  P   I W K+G+ L    R+  T    L TLSI     DD G Y 
Sbjct: 24171 GQDLKIEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYG 24228

Query: 2717  CKATNLLGEAVSTASIKI 2734
                 N++G+   TASI+I
Sbjct: 24229 ITVANVVGQ--KTASIEI 24244



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 19/63 (30%), Positives = 32/63 (50%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G +   ++   G P+P ++W K+G  L  S       T N  TL ++N +K   G YT++
Sbjct: 28505 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 28564

Query: 340   AEN 342
              +N
Sbjct: 28565 LDN 28567



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
             +  G+  R    V GRP P VTWF +  +I    N +I  +  G+ +L + + T    GV
Sbjct: 28897 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI-TDVLGSTSLFVRDATRDHRGV 28955

Query: 463   VTCVARNKSGETAFQCRLNVIEKE-QVVAP 491
              T  A+N SG    + ++ V +   +VV P
Sbjct: 28956 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 28985



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ GA  +  +   G P P   W K    L  S + +I TT + +TL V N  ++D+G Y
Sbjct: 29296 VRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKY 29353

Query: 337   TLLAENPNG 345
             TL  EN +G
Sbjct: 29354 TLTVENNSG 29362



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 4/93 (4%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-DFGLVTL 2702
            F   +K+Y +++EG  V    ++     P  KI W+K+G  +  G R +  F   G  +L
Sbjct: 1293 FDLRIKNY-RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASL 1349

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             I  +  +D GIYT  A+N+ G A+ +  + +E
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 16/156 (10%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMS 1641
            +KN  I EG    F  ++   S   L K+ WY + K +K G R+  +    G  +L I  
Sbjct: 1297 IKNYRILEGMGVTFHCKM---SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1353

Query: 1642 CLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE-SQHEGALPRLNQLEDTSKYQRH 1700
             LPED G YT  A N  G A+ SG         +Y+E +   GA   +  LE  S+ +  
Sbjct: 1354 VLPEDEGIYTAFASNIKGNAICSG--------KLYVEPAAPLGAPTYIPTLEPVSRIR-- 1403

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
            S     ++++P+   P +      + A    AR+ P
Sbjct: 1404 SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSP 1439



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 43/165 (26%), Positives = 64/165 (38%), Gaps = 9/165 (5%)

Query: 3351 NSGEYECVATNKLGRDSTKANLKCTSKEN---LILDSQLPRGMEGGLEKLQTLEDSMVRR 3407
            N+ E      NKL     K   KC   +N   L++D       +G     + L DS    
Sbjct: 4314 NAKEVNWYFENKLVPSDEK--FKCLQDQNTYTLVIDKVNTEDHQGEYV-CEALNDSGKTA 4370

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
                +   K  APV    +  +E +  G  A F   +     PN++ +W+  G+ +    
Sbjct: 4371 TSAKLTVVKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESD 4427

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            +           LEI  T   D GEY C+A N YG    TA++ V
Sbjct: 4428 KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4472



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 3/103 (2%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            KP +I  +      +  +V HLE QV+   D  + + W  +G+ L  G  +K+  +    
Sbjct: 4570 KPHFIKELEPVQSAINKKV-HLECQVD--EDRKVTVTWSKDGQKLPPGKDYKICFEDKIA 4626

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
            TL++     +DSG Y C A N+ G +  S+TV      + +++
Sbjct: 4627 TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKK 4669



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 44/152 (28%), Positives = 66/152 (43%), Gaps = 13/152 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P FVT+P S ++V+ G  V  +   +  T   L + WFK  + +  G       +    +
Sbjct: 5133 PSFVTKPGS-KDVLPGSAVCLKSTFQGSTP--LTIRWFKGNKELVSGGSCYITKEALESS 5189

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L++  +   DSG YTC+  N+ G  E S  L  +     V        LE  Q+L+   K
Sbjct: 5190 LELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEK------LEPSQLLK---K 5240

Query: 1564 YHRTDMVDEVTTQAPICTTSLKN-VEIKEGQR 1594
               T +  +VT   PI  T   N  EIKE  +
Sbjct: 5241 GDATQLACKVTGTPPIKITWFANDREIKESSK 5272



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   I+   S++ GG A F+A L+  G   + V WLKD   +     I   F    
Sbjct: 5411 EPPSFIKKIESTSSLR-GGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTFENNV 5467

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011
             +L +  + V   G Y C+A N  G    SA L++     I  E+
Sbjct: 5468 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEA 5512



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 9/135 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+  +  S + P  IT+      + +G  A  + +     +  +  +WF +G++L  G +
Sbjct: 5494 QRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKE--ITAKWFKDGQELTLGSK 5551

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGM 3390
            Y+      + IL I+   +++SGEY     N +GR S KA +        +LD  +P   
Sbjct: 5552 YKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARIN-------VLDLIIPPSF 5604

Query: 3391 EGGLEKLQTLEDSMV 3405
               L+K+ +++ S +
Sbjct: 5605 TKKLKKMDSIKGSFI 5619



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 9/140 (6%)

Query: 1134 TVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGK 1193
            T++ RS +D    H G Y  T   +    VE  Y    +   +P  +   +    V+E  
Sbjct: 6031 TLQIRS-VDNG--HSGRY--TCQAKNESGVERCYAF--LLVQEPAQIVEKAKSVDVTEKD 6083

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
             + LEC +   G P ++V+W  +G+ +     F   ++    +  I      D+G+YT +
Sbjct: 6084 PMTLECVVA--GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFK 6141

Query: 1254 AVNHLGSAHTSAIVRVIERS 1273
              N  GS+   A +RV++++
Sbjct: 6142 VENDFGSSSCDAYLRVLDQN 6161



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 22/93 (23%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP FT ++   +D   G  +H +C+V   G   +   WF +G+  +T ++   +     +
Sbjct: 6163 PPSFTKKLT-KMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSV 6219

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L+++ +   D   YTC+ +N  G    +  +T
Sbjct: 6220 SLEVNNLELEDTANYTCKVSNVAGDDACSGILT 6252



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 24/99 (24%), Positives = 48/99 (48%), Gaps = 3/99 (3%)

Query: 1706 VITQAPVFTMPMKDIRVAE-NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            ++T+ P F   ++  ++ +   ++  E ++   G P++RV W RN   + AS++      
Sbjct: 6345 LVTEPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFI 6402

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
                 + M  ++ EDSG + C A N  G    S+ + V+
Sbjct: 6403 DSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 6441



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P  + E  G   V  G+T   EC+V     P L +E+Y +GK L S+ +   +F     S
Sbjct: 6630 PAVIVEKAGPMTVTVGETCTLECKVAGT--PELSVEWYKDGKLLTSSQKHKFSFYNKISS 6687

Query: 2302 LDIQHCVPEDAGEYSVKAINALG--HCTSAISMT 2333
            L I     +DAG Y+ +  N +G   CT+ + ++
Sbjct: 6688 LRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVS 6721



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 3/146 (2%)

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE 1858
            T F  +  +LQL S   S +     +  +          + V + P F+ +   P ++  
Sbjct: 6775 TTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE-PLEVLP 6833

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G++  +   I   P    +V W+   + L  G R     +   A L++  +    SGEYT
Sbjct: 6834 GKNVTFTSVIRGTPP--FKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 6891

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIR 1944
            C   NN GQA  + RL V+   + ++
Sbjct: 6892 CVVSNNAGQASCTTRLFVKEPAAFLK 6917



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 2/101 (1%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ + + P+F+  L+ +    +G+S   E ++    ++   V W+ N  ++  + +    
Sbjct: 7284 QLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIK--VSWFRNDSELHESWKYNMS 7341

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                   L I    AEDSG Y   A N  G+A  S ++TV+
Sbjct: 7342 FINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVK 7382



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 3/99 (3%)

Query: 1707 ITQAPVFTMPMKDIRVA-ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + P F   ++  +VA + ++   E ++   G P+++V W RN   +  S +       
Sbjct: 7287 VKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFIN 7344

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
                L +   + EDSG Y C A N +G+A  S+ L V++
Sbjct: 7345 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 7383



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 2/86 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F      V A++G  +  +  I   G P  ++ W+K+ + +  S +F    +  
Sbjct: 7381 VKAPPVFTQKPSPVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHF 7438

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATG 718
              SL +L+L   D GEY C+A +  G
Sbjct: 7439 DTSLHILNLEASDVGEYHCKATNEVG 7464



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 3/99 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  Q++DV + V G    F+   +   +P + V W+ +GK L      +T       
Sbjct: 8983 PPSFSRQLRDVQETV-GLPVVFDCA-ISGSEP-ISVSWYKDGKPLKDSPNVQTSFLDNTA 9039

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379
             L+I       +G+Y C ATN +G  S+ A L  T  +N
Sbjct: 9040 TLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN 9078



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 14/144 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+   + +E S +           L +   +  D G Y        G    S KL  +
Sbjct: 9615 LSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIASAKLTVI 9670

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            +      P +  H+Q++  LK+GQ+    C       P++K EW+ NG+ ++   R KT 
Sbjct: 9671 E------PAWERHLQDVT-LKEGQTCTMTCQF---SVPNVKSEWFRNGRILKPQGRHKTE 9720

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCR 3225
             +     L IA  +  D G+Y C+
Sbjct: 9721 VEHKVHKLTIADVRAEDQGQYTCK 9744



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 1/102 (0%)

Query: 245   VGESDVQISTEIDRSLGPVSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             VG+      T+       ++PP +    R+   ++ G       + SG P+P+V+WFK+ 
Sbjct: 17724 VGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDE 17783

Query: 304   QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               ++  ++  I TT     L     ++SDSG Y ++ EN  G
Sbjct: 17784 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTG 17825



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 24/75 (32%), Positives = 36/75 (48%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             ++ R E    G+P P  KW +    +  S    +H   + SILII+ V  +DS  ++  A
Sbjct: 19841 KKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTA 19900

Query: 4486  ENRGGTAKCSANLVV 4500
             EN  GT      +VV
Sbjct: 19901 ENSSGTDTQKIKVVV 19915



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 1/80 (1%)

Query: 500   LNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             L ++ G+ +VLNA ++ G P P+ +W K G  I P+   +I +   +S L I  A   DA
Sbjct: 21315 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDA 21374

Query: 559   AWYQCTAQNVAGSTATRARL 578
               Y  TA N  G+     ++
Sbjct: 21375 GEYTITATNPFGTKVEHVKV 21394



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 79/385 (20%), Positives = 146/385 (37%), Gaps = 32/385 (8%)

Query: 644   KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI 703
             K +    GG +     I+  G PT +++W K    I  ++       F  + LD  ++N 
Sbjct: 23877 KIINIRAGGSLRLFVPIK--GRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNR 23932

Query: 704   QDSGEYTCRAVSATGVAETKAVLHV----TPRATIERTSQHPETLQYIQQ---LEDYSKY 756
              DSG+YT    +++G       + V    +P   ++ T    +++    +   L+  SK 
Sbjct: 23933 YDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKI 23992

Query: 757   QHQESIEEQTSQRPQFIRPLQD-------LGELQEGRNAHFEAQLTP---VSDPTMRVEW 806
             ++   +E++ + R  +   + +       + +LQEG + +F         +  P    + 
Sbjct: 23993 KNY-IVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADP 24051

Query: 807   YKDGRPITASSRITSIFNFGYVSLNIMHLRAE-DAGS----YTVRAVNKLGEAISTASIR 861
              K         +IT + +    S+++   + E D GS    Y V    K  E  S  + R
Sbjct: 24052 IKVAEVPQPPGKIT-VDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA-R 24109

Query: 862   VAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISI 921
             V +   V  +L   E+  +                       +   +P+ K P     S+
Sbjct: 24110 VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK-PAFSSYSV 24168

Query: 922   KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
             + G     E  +   G     + W KDG P++ ++RI    +     L+IK     D G 
Sbjct: 24169 QVGQDLKIEVPIS--GRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQ 24226

Query: 982   YTCRAYNAIGQATTSANLTIVTKKD 1006
             Y     N +GQ T S  +  + K D
Sbjct: 24227 YGITVANVVGQKTASIEIVTLDKPD 24251



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 3430 ENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPE 3488
            + + +G +AHF  R+    DP  + EWY NG  ++   R   +     V  L I     E
Sbjct: 2087 QTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2144

Query: 3489 DSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            DS   + +A N  GE  + A + VQ K+ I    +L   +    D +A  E
Sbjct: 2145 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFE 2195



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PV    +  LE +  G  A F C ++  + P++   WF  G++I    +          +
Sbjct: 4383 PVIKRKIEPLE-VALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKCSIRSSKYISS 4439

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L+IL T   D G Y CKA+N+ G    T TL V
Sbjct: 4440 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4472



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 633  VYPPPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V  PP F+  +  S   + G       +++  G P +++ W KN + +  S+     F  
Sbjct: 4660 VREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVN 4717

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATG 718
                LD+  + ++DSG Y+C AV+  G
Sbjct: 4718 SEAILDITDVKVEDSGSYSCEAVNDVG 4744



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 2/83 (2%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F++ +     +  G +A    +L     P ++V W+K+ + ++ S+ +   F      
Sbjct: 4664 PSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 4721

Query: 830  LNIMHLRAEDAGSYTVRAVNKLG 852
            L+I  ++ ED+GSY+  AVN +G
Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVG 4744



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 2/87 (2%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V +   F+ +L     L +G +    C++   P   +++ W+ N + ++   ++R S   
Sbjct: 5222 VKEPATFVEKLEPSQLLKKGDATQLACKVTGTPP--IKITWFANDREIKESSKHRMSFVE 5279

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLG 1926
              A L +  V  EDSGEY C+A N  G
Sbjct: 5280 STAVLRLTDVGIEDSGEYMCEAQNEAG 5306



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 4/83 (4%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
            +G    L C++   G   +++ WF N + IK   + R ++      L L  V  EDSG Y
Sbjct: 5240 KGDATQLACKV--TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEY 5297

Query: 1384 TCQATNQLGEAVTSCALRVIAKK 1406
             C+A N+ G     C+  VI K+
Sbjct: 5298 MCEAQNEAGS--DHCSSIVIVKE 5318



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 2/104 (1%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP FT     +   + S    EC  I      + ++WF + + +    + K         
Sbjct: 5601 PPSFTKKLKKMDSIKGSFIDLEC--IVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
            LEI  +   D+G YTC ATN+ G    S  L VK     + +PQ
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 5702



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/117 (27%), Positives = 45/117 (38%), Gaps = 3/117 (2%)

Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228
            IE   K  P F++ L  P  V +  ++ LEC  E  G P   V W  N R +    ++  
Sbjct: 5874 IELKVKEPPTFIRELK-PVEVVKYSDVELEC--EVTGTPPFEVTWLKNNREIRSSKKYTL 5930

Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAI 1285
                    L I     +DTGEY     N  GS   S  V + E    +   +N   +
Sbjct: 5931 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTV 5987



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 2/114 (1%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F   +K + V +      E  +   G P   V WL+N   I +S + T      
Sbjct: 5878 VKEPPTFIRELKPVEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTDRVS 5935

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
               L++   +P D+G Y C   NE G    S+ + ++   S   + ++ + + K
Sbjct: 5936 VFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLK 5989



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L  +   +  ++  EC V  +  P  ++ W  NN+ + S  +Y  T   S  +L I
Sbjct: 5884 FIRELKPVEVVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHI 5941

Query: 2836 THTYEEDSGIYTCKATNSKGSATTS 2860
            T     D+G Y C  +N  GS + S
Sbjct: 5942 TKCDPSDTGEYQCIVSNEGGSCSCS 5966



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I K  PVF    S PP V   KN  +    E  G P   V W+ + R +    ++K    
Sbjct: 6439 IVKEPPVFS---SFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASK 6495

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
                ++ I++  ++D GEY  +A N +GS      V++ E
Sbjct: 6496 NFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE 6535



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP F+ + + + +++ G++  F +  V    P  KV WF   ++L  G R   + +  +
Sbjct: 6818 EPPSFVKEPEPL-EVLPGKNVTFTS--VIRGTPPFKVNWFRGARELVKGDRCNIYFEDTV 6874

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L++       SGEY CV +N  G+ S    L
Sbjct: 6875 AELELFNIDISQSGEYTCVVSNNAGQASCTTRL 6907



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 5/115 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P F   ++ +  A   +   + ++   G P++ V W +    +  +    T       
Sbjct: 7004 EPPYFVTELEPLEAAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTNNVA 7061

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQ 1823
             L    VN  DSG YTC+A N +G A + +   +Q +   QL       L+ I+Q
Sbjct: 7062 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER---QLPPSFARQLKDIEQ 7113



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 2/89 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++ L  +    GD++  +C V  +  P + + W+  +  L     Y++    +  +L  
Sbjct: 7008 FVTELEPLEAAVGDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYFTNNVATLVF 7065

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLR 2864
                  DSG YTCKA NS G+A++    R
Sbjct: 7066 NKVNINDSGEYTCKAENSIGTASSKTVFR 7094



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1864 YECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923
            +ECRI    +P ++V WY +G +L+     +TS     A L IL       G+Y C A N
Sbjct: 8062 FECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASN 8119

Query: 1924 NLGQAVSSIRLNVQSKE 1940
             LG A SS +L +   E
Sbjct: 8120 PLGTASSSAKLILSEHE 8136



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 2/95 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++ L     V + +    EC++   G P ++V W+ +   +   S+F+  +      
Sbjct: 8232 PRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDSVAV 8289

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            L++ + +  D+G+YT  A N  GSA +S  ++V E
Sbjct: 8290 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE 8324



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P F +    ++ + GTNV     ++  G     V WF     +  G R   + E
Sbjct: 8696 LTVREPPSFVQKPDPMDVLTGTNVTFTSIVK--GTPPFSVSWFKGSSELVPGDRCNVSLE 8753

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                 L+L  V    SG YTC  +N+ G+A  SC   +  K
Sbjct: 8754 DSVAELELFDVDTSQSGEYTCIVSNEAGKA--SCTTHLYIK 8792



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 38/133 (28%), Positives = 62/133 (46%), Gaps = 12/133 (9%)

Query: 3553 ESGNPPEFTT--TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN 3610
            E  NPP F     P D ++ E  SA FEC +       ++V W  + + + +G + +   
Sbjct: 9075 EGKNPPFFDIRLAPVDAVVGE--SADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISY 9130

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTE 3670
                  L +  V + D+G YTC A N  G+ + + +L +K R    L P  PS  K  +E
Sbjct: 9131 LENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER----LIP--PSFTKRLSE 9184

Query: 3671 SIQKLEETLHKRE 3683
            ++++ E    K E
Sbjct: 9185 TVEETEGNSFKLE 9197



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 3/105 (2%)

Query: 1311 PQFSRAL-HNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            P F++ L   +E  EG +  LE R+   G Q + V W+ N   I+        ++ + + 
Sbjct: 9176 PSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 9233

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
            L +      D+G+YTC+ +N  G A+ + ++ +   K   +  QH
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH 9278



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/63 (34%), Positives = 34/63 (53%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P   V W+KDG+ + AS R+T   +     L +      DAG YT+   NKLG A ++ +
Sbjct: 15341 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 15400

Query: 860   IRV 862
             ++V
Sbjct: 15401 VKV 15403



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 4622  PPEIIEPL--KDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             PPE+   +  +D I V  GQ I    ++ G+P P + W K  K++   K   + +     
Sbjct: 18832 PPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV 18891

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNL 4721
              L+I EA   D G Y   A NS+G    +A + V  +P    NL
Sbjct: 18892 ELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNL 18935



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 21/68 (30%), Positives = 38/68 (55%)

Query: 278   QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337
             +E ++ + ++ + G P P V+W K    L    +  + ++  +TTL V + QKSD+G YT
Sbjct: 20922 KENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYT 20981

Query: 338   LLAENPNG 345
             +  +N  G
Sbjct: 20982 ITLKNVAG 20989



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 6/88 (6%)

Query: 71    PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYN-EQTGDV 129
             PP F+ +F       G + K +    G PTP V+W +   PL    K + R N E T + 
Sbjct: 23074 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL----KQTTRVNAESTENN 23129

Query: 130   SLL-IKQIGPGDEGEYTCTARNQYGEAI 156
             SLL IK     D G Y     N  GEAI
Sbjct: 23130 SLLTIKDACREDVGHYVVKLTNSAGEAI 23157



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHD 1097
            TQ P F  PL+    ++EG +A FEA +         V W+ +G+ I+++    +Q    
Sbjct: 3    TQAPTFTQPLQSV-VVLEGSTATFEAHISGFP--VPEVSWFRDGQVISTSTLPGVQISFS 59

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             G   L I +V   +SG Y++ A N +G+A  +A + V+  ++
Sbjct: 60   DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 11/139 (7%)

Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            +IE+  P +  P+    ++  T V +G  AHF  +V  V  P+   E+Y NG  ++ + R
Sbjct: 2068 KIELS-PSMEAPKIFERIQSQT-VGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDR 2123

Query: 2291 FHITFDFGYV-SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG 2349
             +  +    V  L I+    ED+    VKAIN  G  +S   + V AK  I    +  + 
Sbjct: 2124 IYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDV 2183

Query: 2350 LEKIR------ELESAEPF 2362
            + K +      E E++EPF
Sbjct: 2184 VAKEKDTMATFECETSEPF 2202



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            V   KI +KP++    E A   F+V +S +  P V WF     +  S+KH +++      
Sbjct: 2792 VETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHK 2850

Query: 323  LRVRNTQKSDSGHYT 337
            L ++N   SD+G YT
Sbjct: 2851 LMLQNISPSDAGEYT 2865



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 34/145 (23%), Positives = 62/145 (42%), Gaps = 6/145 (4%)

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIK 1985
            + V+S  ++ + ++  ++ S+ +         E+ +  K    +  F+ E  P    P+ 
Sbjct: 4237 KGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLV 4296

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            +    EG  VHL  ++T   +    V WY   + V    +FK   D     L I     E
Sbjct: 4297 DTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE 4352

Query: 2046 D-TGTYMCKATNAVGEAVTTSSVKV 2069
            D  G Y+C+A N  G+  T++ + V
Sbjct: 4353 DHQGEYVCEALNDSGKTATSAKLTV 4377



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 2/125 (1%)

Query: 1278 DTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPV 1337
            +T++ Q     + L D+ +     +  +    AP   R +  +E   G      C +Q  
Sbjct: 4350 NTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA 4409

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             +  +R +WF  G+ I    +          +L++L     D G YTC+A+N+ G    +
Sbjct: 4410 PN--VRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT 4467

Query: 1398 CALRV 1402
              L V
Sbjct: 4468 ATLTV 4472



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P FI  L+ V +    K+H E +++   D  + + W K+GQ +     +   F     +L
Sbjct: 4571 PHFIKELEPVQSAINKKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 4628

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++    ++DSG Y C A +  G +   A + V
Sbjct: 4629 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 4660



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 2/92 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  ++  +  +  G      C+++  G P +++ WF N +  +  + V         
Sbjct: 4663 PPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSEA 4720

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             LDI  +   D+G Y+C A N  GS + + +I
Sbjct: 4721 ILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 4752



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 3/102 (2%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F   LR    V  G T   +C++       +R+ ++ +GK + ++ R+ I F  G  S
Sbjct: 5040 PFFTKPLRNVDSVVNG-TCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISE 2343
            L+I      DAG ++ +A N++G   S+ ++ V    S +++
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTK 5138



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 3/98 (3%)

Query: 1707 ITQAPVFTMPMKDIRVAEN-QAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + P F      + V  N Q+  FE ++   G PK+RV W  +G  I A  +       
Sbjct: 5784 VKEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFID 5841

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            G     +     E+SGTY C A N+ G A  S  L V+
Sbjct: 5842 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 5879



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 3/103 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP F+ EL+    V +      EC+V     P   + +  N + ++S+ ++ +T      
Sbjct: 5881 PPTFIRELK-PVEVVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTLTDRVSVF 5937

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISE 2343
            +L I  C P D GEY     N  G C+ +  + +    S I +
Sbjct: 5938 NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKK 5980



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L  +D +  G + H +C++   G   +  +WF++ K I  S++         VS
Sbjct: 6164 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            + ++++  ED   Y C+ SN+ G+
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAGD 6244



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 2/99 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V + P F   L++   +  G    LE ++     P +++ WF+N   L    + + TF  
Sbjct: 6346 VTEPPKFVKKLEASKIVKAGDSSRLECKIAG--SPEIRVVWFRNEHELPASDKYRMTFID 6403

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             +  + +N+L  +DSG + C+A N  G    +  + +++
Sbjct: 6404 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE 6442



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 22/94 (23%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP+FV +L  +  V  G ++  EC++     P +R+ ++ N   L ++ ++ +TF     
Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 6406

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             + + +   ED+G++  +A N  G  + +  + V
Sbjct: 6407 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIV 6440



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 2/100 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  P   +     +T   G     E ++   G P + +EW K+G+ + +S +    F   
Sbjct: 6627 VLEPAVIVEKAGPMTVTVGETCTLECKV--AGTPELSVEWYKDGKLLTSSQKHKFSFYNK 6684

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
              SL +LS+  QD+G YT +  +  G +   AV+ V+ RA
Sbjct: 6685 ISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA 6724



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 3/98 (3%)

Query: 2104 QPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD 2163
            +P + P F     S++ +  G+ A FEC V       +T  W  + ++IR G  Y  T  
Sbjct: 7193 EPKKSPFFDIKPVSIDVIA-GESADFECHVTGAQPMRIT--WSKDNKEIRPGGNYTITCV 7249

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 L IL     DSG Y C+ATN +G+ + +  L V
Sbjct: 7250 GNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 7287



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 3/104 (2%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F  +P SI+ VI G+   FEC +       +++ W K+ + +  G  +          
Sbjct: 7198 PFFDIKPVSID-VIAGESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPH 7254

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
            L I+ +   DSG YTC+A N VG D  S +L+ +     V+  +
Sbjct: 7255 LRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLE 7298



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 2/111 (1%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP   TQ   P    +G     +C I   P     V W  + K +++  +++ ++    
Sbjct: 7382 KAPPVFTQKPSPVGALKGSDVILQCEISGTPP--FEVVWVKDRKQVRNSKKFKITSKHFD 7439

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952
             +L IL +   D GEY CKA N +G    S  +  +     ++     S L
Sbjct: 7440 TSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTL 7490



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P+F      IE L+ G + H E  L  T  P   V WY + + L++G +++   +     
Sbjct: 8326 PIFRKKPHPIETLK-GADVHLECELQGT--PPFHVSWYKDKRELRSGKKYKIMSENFLTS 8382

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            + I      D GEY C+A N+ G      S+ ++
Sbjct: 8383 IHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 8416



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 781  ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
            E  +G + H E +L     P   V WYKD R + +  +   +      S++I+++ A D 
Sbjct: 8336 ETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADI 8393

Query: 841  GSYTVRAVNKLGEAISTASIRVAA 864
            G Y  +A N +G      SI + A
Sbjct: 8394 GEYQCKATNDVGSDTCVGSIALKA 8417



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN-GKPIKTGHRFRPAY 1363
            I +   P+F + L +I TV G  V L+  ++  G + + V WF + G+ ++       +Y
Sbjct: 8413 IALKAPPRFVKKLSDISTVVGKEVQLQTTIE--GAEPISVVWFKDKGEIVRESDNIWISY 8470

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409
              +   L    V P ++G YTCQ  N  G       L V+    ++
Sbjct: 8471 SENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV 8516



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            + + P F   L+   K+  G    L+ Q+     P + + W+K    L      K  F  
Sbjct: 8884 ILEPPYFVKQLEPV-KVSVGDSASLQCQLAGT--PEIGVSWYKGDTKLRPTTTYKMHFRN 8940

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             + TL  N +  +DSG Y CKA N +GE  ++  + ++++
Sbjct: 8941 NVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 8980



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 1/104 (0%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P FT  + +  V E +   F+      G   + V W +N + I+ ++          + L
Sbjct: 9176 PSFTKRLSET-VEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVL 9234

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814
             ++     D+G YTC+  N+ G A+ +S++ ++      +  QH
Sbjct: 9235 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH 9278



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 3/89 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            ++P + PVF   LT +  + EG+     C V+  ++P + I W   G++I+   R   + 
Sbjct: 9267 KEPKKPPVFDQHLTPV-TVSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSF 9323

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLG 2191
              G   L++      DSG Y+CKA+N  G
Sbjct: 9324 ASGTAVLELRDVAKADSGDYVCKASNVAG 9352



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%)

Query: 2779 HLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHT 2838
            HL ++  KEG      C       P +K EWF N + L    R+K+  +     L I   
Sbjct: 9677 HLQDVTLKEGQTCTMTCQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADV 9733

Query: 2839 YEEDSGIYTCKATNSKGSA 2857
              ED G YTCK  + + SA
Sbjct: 9734 RAEDQGQYTCKYEDLETSA 9752



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/130 (30%), Positives = 58/130 (44%), Gaps = 9/130 (6%)

Query: 4583  KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             K+  +A+N+AGE+  D   V      KD+ +P     +A        +++ +  G  +  
Sbjct: 18113 KFRVLAVNAAGES--DPAHVPEPVLVKDRLEPPELILDA-----NMAREQHIKVGDTLRL 18165

Query: 4643  SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
             S  I G P P V W K D+   P+K  ++  T     L I  A  ED G Y     N AG
Sbjct: 18166 SAIIKGVPFPKVTWKKEDR-DAPTK-ARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAG 18223

Query: 4703  RVTVAAKLKV 4712
               TV+ K+ V
Sbjct: 18224 SKTVSVKVLV 18233



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 4495  SANLVVEEKRRQGRGGIV------PPSFTL--TAQNV-NVTSGQLVRLDTKVTGTKPIDV 4545
             +AN+V E + R+    ++      PP   L  T ++V  V  GQ +R+  +V G    D+
Sbjct: 18808 AANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDI 18867

Query: 4546  YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
              W K GK +  + R  ++++     L I EA   D GKY   A NS+G A+  A
Sbjct: 18868 TWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSA 18921



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 22/63 (34%), Positives = 32/63 (50%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G + + ++ + G P+P VTW K  Q L  + +    TT   T L +    +SDSG Y L 
Sbjct: 22007 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 22066

Query: 340   AEN 342
             A N
Sbjct: 22067 ARN 22069



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P++        V  GQ ++    I G+P PT+ W K    +K +    ++ + D  TL I
Sbjct: 24157 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 24216

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVTVAAKL-KVTQPD 4716
              E   +D G Y     N  G+ T + ++  + +PD
Sbjct: 24217 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD 24251



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 50/213 (23%), Positives = 83/213 (38%), Gaps = 10/213 (4%)

Query: 797   VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAE-DAGS----YTVRAVNKL 851
             V  P   V+  K   P +   ++T + +    S ++M  + E D GS    Y V    K 
Sbjct: 25124 VGVPVETVDAVKAAEPPSPPGKVT-LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKG 25182

Query: 852   GEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEF 911
              E  S  +      + VT  L   ++ ++  K                    + T +P  
Sbjct: 25183 TEKWSIVAESKVCNAVVTG-LSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSL 25241

Query: 912   KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTI 971
             K P  +  SI+ G     E  +  IG     + W+KDG P++ ++R+          L I
Sbjct: 25242 KLPF-NTYSIQAGEDLKIE--IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 25298

Query: 972   KSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
             K     D G YT  A N+ G AT + ++ ++ K
Sbjct: 25299 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 25331



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 482   VIEKEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
             +I K+ V  P+    V+    + V+ GE + +NA   G P P I+W KDG+ I       
Sbjct: 26705 IIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTE 26764

Query: 539   IHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             I +    + L +      D   Y  T +NVAG+
Sbjct: 26765 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGT 26797



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/108 (22%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +++ +  T  P     L+++ +++G +   + R+  +   T  V++Y +   ++S   F 
Sbjct: 94   ELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQ 151

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             +      +L I    PEDSGTY+  A N++G A ++   +V  ++ +
Sbjct: 152  ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 8/127 (6%)

Query: 619  ERARPYIPPGEEDRVYPPPQFIVP-----LKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            E  +  IP  + D++   P    P     ++S T  +G   HF  R+  VG P  + EW 
Sbjct: 2055 EEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRV--VGKPDPECEWY 2112

Query: 674  KNGQSIEASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            KNG  IE S R    +       L +  +  +DS     +A++  G   + A L V  + 
Sbjct: 2113 KNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172

Query: 733  TIERTSQ 739
             I  T +
Sbjct: 2173 LITFTQE 2179



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/130 (22%), Positives = 57/130 (43%), Gaps = 4/130 (3%)

Query: 3793 IVLESQLPQGMSGEKIKEL--ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850
            +V++    +   GE + E   + G+ + + K   +    P    +I+   V      +F 
Sbjct: 4344 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFT 4403

Query: 3851 CRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910
            C ++    P +R +W++ G+ +    +          SL+IL     D GEY C+A N++
Sbjct: 4404 CEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4461

Query: 3911 GEDFTKATIS 3920
            G     AT++
Sbjct: 4462 GSVSCTATLT 4471



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 20/70 (28%), Positives = 36/70 (51%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P ++V W +N   +  SN +          L++  V  EDSG+Y+C A+N++G    S
Sbjct: 4690 GSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCS 4749

Query: 1798 STLFVQSKAS 1807
            + + ++   S
Sbjct: 4750 TEIVIKEPPS 4759



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/63 (38%), Positives = 32/63 (50%)

Query: 2798 EPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSA 2857
            E +  P  +I WF +N  L SG +YK+      VSL I      D+G Y C+ TN  GS+
Sbjct: 5342 EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 5401

Query: 2858 TTS 2860
              S
Sbjct: 5402 ICS 5404



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/110 (23%), Positives = 57/110 (51%), Gaps = 3/110 (2%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096
            V + + P F+  ++ T+ +  G +A F+A ++    L +TV W  +  +IT  + I+   
Sbjct: 5407 VTLREPPSFIKKIESTSSL-RGGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTF 5463

Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSI 1146
            +    +L ++ +  +  G Y   A+N AG  + SA ++V+  ++I   ++
Sbjct: 5464 ENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAV 5513



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 38/147 (25%), Positives = 66/147 (44%), Gaps = 15/147 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GF 3752
            PP+F  +    + +  G    F+C++   G P +R+ W+ +G    T  + H ++   G 
Sbjct: 5787 PPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEI-TAIQKHGISFIDGL 5843

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
                I      ++G Y C A N  G+A      +CS    I L+ + P     E +K +E
Sbjct: 5844 ATFQISGARVENSGTYVCEARNDAGTA------SCS----IELKVKEPPTFIRE-LKPVE 5892

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSH 3839
              + SD   E  +  TPP  +T +K++
Sbjct: 5893 VVKYSDVELECEVTGTPPFEVTWLKNN 5919



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/122 (21%), Positives = 61/122 (50%), Gaps = 4/122 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P FT  L+ ++ +  G + H E +++ +    +  +W+ +GK +   +++R  C    V 
Sbjct: 6164 PSFTKKLTKMDKVL-GSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGM-EGTIDKIAAL 3538
            LE++    ED+  Y C+  N  G+   +  + V+   + +++    + + + T++  A L
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAIL 6280

Query: 3539 EG 3540
            +G
Sbjct: 6281 KG 6282



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   LT ++ +  G   H EC+V       ++  WF +G++I    +YR       V+
Sbjct: 6164 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 2169 LDILYTYAEDSGTYMCKATNKLGE 2192
            L++     ED+  Y CK +N  G+
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAGD 6244



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 6/138 (4%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            V  K+PPRFV+++ S T +V  E  + +  +   G   + V+W    + ++ ++    I 
Sbjct: 6531 VKLKEPPRFVSKLNSLT-VVAGEPAELQASIE--GAQPIFVQWLKEKEEVIRESENIRIT 6587

Query: 4027 DFGYVA-MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIE 4085
                VA + F    P ++G+Y+C+  N  GM+E  A +    +P ++ +   P  + ++ 
Sbjct: 6588 FVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVL-EPAVIVEKAGPMTV-TVG 6645

Query: 4086 KIREMEASWQVTPEQVVE 4103
            +   +E     TPE  VE
Sbjct: 6646 ETCTLECKVAGTPELSVE 6663



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 2/113 (1%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            +P  I+  A    +  G+   LE +V     P+L +EWY +GK+L    + K +      
Sbjct: 6629 EPAVIVEKAGPMTVTVGETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKIS 6686

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022
            +L ++ V  +D+G YT +  N  G++  ++ V  + +      T+  K T G+
Sbjct: 6687 SLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGV 6739



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP FT    +      +S   EC++     S + V WFH    +++G++ +T        
Sbjct: 6726 PPSFTRRLKNTGGVLGASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCT 6783

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
            L++  +   D G YTC A N  G       L V+     + EP+
Sbjct: 6784 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 6827



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 4/95 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +K+ E T G PV L   L       ++V WY +G  ++     +T++      L
Sbjct: 7102 PSFARQLKDIEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDDENLQTSFVDNVATL 7159

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             IL      +G Y C A+N +G A  +SS ++ A+
Sbjct: 7160 KILQTDLSHSGQYSCSASNPLGTA--SSSARLTAR 7192



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 37/143 (25%), Positives = 63/143 (44%), Gaps = 6/143 (4%)

Query: 1663 TSGIAIVHSKKSIYLESQHEG--ALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDI 1720
            TS +  V + K +  +  H G  +    N L   S   R +A++    ++P F +    I
Sbjct: 7150 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREP--KKSPFFDIKPVSI 7207

Query: 1721 RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDS 1780
             V   ++A FE  +   G   +R+ W ++   I      T         L +  V   DS
Sbjct: 7208 DVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDS 7265

Query: 1781 GTYTCRAINELGEAVTSSTLFVQ 1803
            G YTC+A N++G+ + S+ L V+
Sbjct: 7266 GQYTCQATNDVGKDMCSAQLSVK 7288



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F +        +G  V L+  ++    P   V W  + + V+   +FK T      +L
Sbjct: 7385 PVFTQKPSPVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSL 7442

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
             IL   A D G Y CKATN VG    + SVK
Sbjct: 7443 HILNLEASDVGEYHCKATNEVGSDTCSCSVK 7473



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PVF    + +  LK  D    +C +     P   + W  + +++R   +++ T      +
Sbjct: 7385 PVFTQKPSPVGALKGSD-VILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTS 7441

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
            L IL   A D G Y CKATN++G    +C++K
Sbjct: 7442 LHILNLEASDVGEYHCKATNEVGSDTCSCSVK 7473



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 2/90 (2%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF    + +   +G ++  +C +  S  P  ++ W  + K + +  ++K T      SL 
Sbjct: 7386 VFTQKPSPVGALKGSDVILQCEI--SGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLH 7443

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            I +    D G Y CKATN  GS T S S++
Sbjct: 7444 ILNLEASDVGEYHCKATNEVGSDTCSCSVK 7473



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 2/97 (2%)

Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            FV E   F K + +  V  G P+ LEAT T    P + V W  +   + Q  R   T   
Sbjct: 7849 FVKEPATFVKRLADFSVETGSPIVLEATYT--GTPPISVSWIKDEYLISQSERCSITMTE 7906

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L+IL +  ED   Y C   N  G+ +  + V V
Sbjct: 7907 KSTILEILESTIEDYAQYSCLIENEAGQDICEALVSV 7943



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E    P F   +KD +    G    FE R+   G   L+V W KDG  ++  + + T 
Sbjct: 8036 IKERKLPPFFARKLKD-VHETLGFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTS 8092

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            F      L I        G Y C A N +G A++SA L +
Sbjct: 8093 FVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL 8132



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  +++DV + + G    FE R +   +P L+V W+ +G  L      +T     + 
Sbjct: 8042 PPFFARKLKDVHETL-GFPVAFECR-INGSEP-LQVSWYKDGVLLKDDANLQTSFVHNVA 8098

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
             L IL   + + G+Y C A+N LG  S+ A L  +  E
Sbjct: 8099 TLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 8136



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 5/103 (4%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            SV      V +P+SI+ V  G     EC +    +  L  +WFK+G+ +T  ++++ I  
Sbjct: 8508 SVLEPATIVEKPESIK-VTTGDTCTLECTVAGTPE--LSTKWFKDGKELTSDNKYK-ISF 8563

Query: 1499 FGYVA-LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540
            F  V+ L II++   DSG+Y+    N VG D  +  L     T
Sbjct: 8564 FNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT 8606



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 2/75 (2%)

Query: 793  QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS-LNIMHLRAEDAGSYTVRAVNKL 851
            + T    P +  +W+KDG+ +T+ ++    F F  VS L I+++   D+G Y+    N +
Sbjct: 8533 ECTVAGTPELSTKWFKDGKELTSDNKYKISF-FNKVSGLKIINVAPSDSGVYSFEVQNPV 8591

Query: 852  GEAISTASIRVAARS 866
            G+   TAS++V+ R+
Sbjct: 8592 GKDSCTASLQVSDRT 8606



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 2/100 (2%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P FT  +K+       +   E ++   G P + V W   G  I +  +  T      
Sbjct: 8606 TVPPSFTRKLKETNGLSGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNT 8663

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
             AL +  +   DSG YTC A N  G    S+ L V+   S
Sbjct: 8664 CALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPS 8703



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +K      G  V +E  +     P + V W+  G  +  G +++TT      AL
Sbjct: 8609 PSFTRKLKETNGLSGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTCAL 8666

Query: 2038 DILYAYAEDTGTYMCKATNAVG 2059
             +      D+G Y C ATN  G
Sbjct: 8667 TVNMLEESDSGDYTCIATNMAG 8688



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 2/102 (1%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I +++ P F + L  ++   G +  L+C+L   G   + V W+     ++    ++  + 
Sbjct: 8882 ILILEPPYFVKQLEPVKVSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRPTTTYKMHFR 8939

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
             +   L    V   DSG Y C+A N +GE   S  L V  +K
Sbjct: 8940 NNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK 8981



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 3/100 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++    G  + F+C +  S +P + + W+ + KPL      +++   +  +L+I
Sbjct: 8986 FSRQLRDVQETVGLPVVFDCAISGS-EP-ISVSWYKDGKPLKDSPNVQTSFLDNTATLNI 9043

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKN-IYFD 2874
              T    +G Y+C ATN  GSA++S  L  T  KN  +FD
Sbjct: 9044 FKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFD 9083



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 3/115 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F  ++ S TVEE+EG  F+          + + WY+N   +         +    + 
Sbjct: 9175 PPSFTKRL-SETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 9233

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK--KLPDIILQNQVPRGMKRSE 3941
            L +      D+G Y C+  ND G     ++I  K  K P +  Q+  P  +   E
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGE 9288



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 47/203 (23%), Positives = 85/203 (41%), Gaps = 17/203 (8%)

Query: 4534  DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
             + +  G  PI  Y ++  +  +PD          T + L+         ++   A+N  G
Sbjct: 16244 EPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIG 16303

Query: 4594  EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLP 4652
             E+  +    +++    D+  P  K        +    D I V  G+ +     + G P+P
Sbjct: 16304 ES--EPSLPLNVVIQDDEVPPTIKLR------LSVRGDTIKVKAGEPVHIPADVTGLPMP 16355

Query: 4653  TVQWYKGDKLI-KPSKYFQ-----MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
              ++W K + +I KP+   Q     +SR+  +  L I +A  ED+G Y   A N  G V  
Sbjct: 16356 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 16415

Query: 4707  AAKLKV-TQPDQADNLPALTPLR 4728
                ++V  +P    NL A+T ++
Sbjct: 16416 NVHVEVYDRPSPPRNL-AVTDIK 16437



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/130 (25%), Positives = 63/130 (48%), Gaps = 7/130 (5%)

Query: 4677  EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK--VTQPDQADNLPALT---PLRD-I 4730
             E    +S    +   +++ +A N+AG ++  +     +T  D+ + LP ++     RD I
Sbjct: 24504 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVE-LPRISMDPKFRDTI 24562

Query: 4731  VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             VV  G+  + +  +  K  PTI+WLR    I E+   ++ +    A+L++ +    D G 
Sbjct: 24563 VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 24622

Query: 4791  FTCRATTAAG 4800
             +  RA+  AG
Sbjct: 24623 YILRASNVAG 24632



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 21/78 (26%), Positives = 39/78 (50%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  + E+   G P P I W ++  P+K +    +   +T ++L I++   +D   +   A
Sbjct: 25254 EDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTA 25313

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N  GTA  + +++V EK
Sbjct: 25314 TNSAGTATENLSVIVLEK 25331



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGY 2299
            P F   L+    V EG TA FE  +     P   + ++ +G+ + ++      I+F  G 
Sbjct: 6    PTFTQPLQSVV-VLEGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L I      ++G YS+KA N  G  TS   + V A+ +  +  QR + +   +  +  
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 2360 EPFKRPEIPEPVTR 2373
               +   IP PV +
Sbjct: 123  LQVRVTGIPTPVVK 136



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 1/115 (0%)

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            ++++   P  V     + V EGE      R  G P P++ W  +G  I  +   R+  DG
Sbjct: 1834 DQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1893

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRP 598
                LDI   K+ D    + TA+N  G    + +L            +R   PRP
Sbjct: 1894 -IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRP 1947



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 18/168 (10%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            KD+  +    +A +E S+      ++ ++WF+    I+ S + R V    +  L +    
Sbjct: 2802 KDVTALENATVA-FEVSV---SHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 2857

Query: 3115 TTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174
             +D+G Y+       GQ      LEC  K   +    T  ++NIE + + ++A FEC V 
Sbjct: 2858 PSDAGEYTAVV----GQ------LECKAKLFVETLHITKTMKNIE-VPETKTASFECEVS 2906

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
              + P M   W  NG  +  S + K V       L I  T   DS EY
Sbjct: 2907 HFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEY 2951



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 21/68 (30%), Positives = 30/68 (44%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E  G     + W KD   + +  +  TF     V+L I      DAG Y CR  N +G +
Sbjct: 5342 EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 5401

Query: 994  TTSANLTI 1001
              SA +T+
Sbjct: 5402 ICSARVTL 5409



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 21/66 (31%), Positives = 34/66 (51%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L+V+WLKDG+ +  S   +  F     +  I+SV   D+G YT +  N  G ++  
Sbjct: 6093 GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCD 6152

Query: 997  ANLTIV 1002
            A L ++
Sbjct: 6153 AYLRVL 6158



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 2/78 (2%)

Query: 924  GGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYT 983
            G   H E ++   G   +  +W KDG+ +  S++     +   V+L + ++ + D  +YT
Sbjct: 6178 GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYT 6235

Query: 984  CRAYNAIGQATTSANLTI 1001
            C+  N  G    S  LT+
Sbjct: 6236 CKVSNVAGDDACSGILTV 6253



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            VT  P+FV + ++ + V  G     ECK+       ++V WF+N   +    ++R     
Sbjct: 6346 VTEPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFID 6403

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                + + +L  EDSG + C A N  G+   S ++
Sbjct: 6404 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV 6438



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+F  +++ +  V  G     +C++   G P +R+ WF N        +          
Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 6406

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + ++ +   D+G++ C A N  GS + + K+
Sbjct: 6407 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV 6438



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 2/102 (1%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F  ++K+           EC+V       + + W+     + SG +Y+T +    
Sbjct: 6724 AVPPSFTRRLKNTGGVLGASCILECKVAGSSP--ISVAWFHEKTKIVSGAKYQTTFSDNV 6781

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
             +L +  + + D G Y C A N  G D  +A ++ ++ P  +
Sbjct: 6782 CTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFV 6823



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  E  + ++V  G  V F   +   G P  +++WF   R    G R +   +    
Sbjct: 6819 PPSFVKE-PEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDTVA 6875

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             L++  I    +GEYTC  +N  G A+ T ++
Sbjct: 6876 ELELFNIDISQSGEYTCVVSNNAGQASCTTRL 6907



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L  +E    G++   + ++  T  P + V WY     L+    +RT+       
Sbjct: 7006 PYFVTELEPLE-AAVGDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYFTNNVAT 7062

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
            L  +     DSGEY C+A N+ G A +    ++Q ++
Sbjct: 7063 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ 7099



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/109 (22%), Positives = 50/109 (45%), Gaps = 2/109 (1%)

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
            S +    + P+F++ L+     ++G +   E +++    P ++V W+++   +  S +  
Sbjct: 7282 SAQLSVKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYN 7339

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVT 869
              F      L I    AED+G Y   A N +G+A  + ++ V A    T
Sbjct: 7340 MSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFT 7388



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP FI +++DV  ++ G S   E R+       + V WF +G ++  G + ++     + 
Sbjct: 7667 PPSFIRKLKDVNAIL-GASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVC 7723

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             L++      ++G Y CVA N  G D   A L
Sbjct: 7724 TLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 7755



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L ++    G ++  EC V  S    + + WF +   + SG + +S+   +  +L++
Sbjct: 7670 FIRKLKDVNAILGASVVLECRVSGSAP--ISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 7727

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            +     D+GIYTC A N  GS   S  L
Sbjct: 7728 SLLEPSDTGIYTCVAANVAGSDECSAVL 7755



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E PIF +    P E  +G   H E  +   G P     WY +  EL+ G +++   +   
Sbjct: 8324 EPPIFRKK-PHPIETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFL 8380

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             ++ I +V A D G Y CKA N  G
Sbjct: 8381 TSIHILNVDAADIGEYQCKATNDVG 8405



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 23/85 (27%), Positives = 44/85 (51%), Gaps = 2/85 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V+ G    LEC +   G P +  +WF +G+ +T  +++K  +      L II+   +D+G
Sbjct: 8524 VTTGDTCTLECTVA--GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSG 8581

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERS 1273
             Y+    N +G    +A ++V +R+
Sbjct: 8582 VYSFEVQNPVGKDSCTASLQVSDRT 8606



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 3/100 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V + T  P F   +K+   +  G     E ++   G   + V W  +G  + +  +  T 
Sbjct: 8602 VSDRTVPPSFTRKLKETNGLS-GSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTT 8658

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                  ALT+  +   D+G YTC A N  G    SA LT+
Sbjct: 8659 LTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 8698



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L   D +V G+    E  V   T P +K+ W K+   + +G + + ++      
Sbjct: 9080 PFFDIRLAPVDAVV-GESADFECHVTG-TQP-IKVSWAKDSREIRSGGKYQISYLENSAH 9136

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            L++  +   DSG YTC A N +G+   TA + I++R
Sbjct: 9137 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 9172



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F  R   ++ V+ G+   FEC +       +KV W K+ + +  G +++  +      
Sbjct: 9080 PFFDIRLAPVDAVV-GESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLENSAH 9136

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            L ++ +   DSG YTC AVN VG D  + +L  +
Sbjct: 9137 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIK 9170



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984
            EG+ + L   V+  ++P ++I+W   G+ ++   R   +   G   L+L DV + DSG Y
Sbjct: 9286 EGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDY 9343

Query: 2985 TCKAYNKRGEAFTSSTVYCTSKDNLIERTQ 3014
             CKA N  G   T S V    K  +   T+
Sbjct: 9344 VCKASNVAGSDTTKSKVTIKDKPAVAPATK 9373



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 65/284 (22%), Positives = 106/284 (37%), Gaps = 41/284 (14%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G+ A F+  +S +     TW K+G  +  S KH  I       L + + Q SD+G YT  
Sbjct: 12060 GSSAIFECLVSPSTAI-TTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT-- 12116

Query: 340   AENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ 399
                   C++  G     S  +  V++   +++     +  EE + + +        ++ +
Sbjct: 12117 ------CVLRLGNKEKTSTAKLVVEELPVRFV-----KTLEEEVTVVKGQPLYLSCELNK 12165

Query: 400   DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
             +RDV   K  +      GR  P V   +                     AL I +   +D
Sbjct: 12166 ERDVVWRKDGKIVVEKPGRIVPGVIGLMR--------------------ALTINDADDTD 12205

Query: 460   SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519
             +G  T    N +      C + V+E   V+    V+     +V+     +  A  +   T
Sbjct: 12206 AGTYTVTVENANNLECSSC-VKVVE---VIRDWLVKPIRDQHVKPKGTAIF-ACDIAKDT 12260

Query: 520   PRITWQK--DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
             P I W K  D +P  PN +  I  DG    L I  A   D A Y
Sbjct: 12261 PNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY 12304



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 3/97 (3%)

Query: 485   KEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             +E++V P     V+    L V+ G  V   A   G P P   W  DG  I  +    + T
Sbjct: 18429 QEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVET 18488

Query: 542   DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             D  +S L I      D   YQ T  N AGS      L
Sbjct: 18489 DNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHL 18525



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 2648  LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             +KS   +  G +V L+A V  +  P   + W K+G  L     +K      L TL + S+
Sbjct: 20228 MKSLLTVKAGTNVCLDATVFGKPMPT--VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSV 20285

Query: 2708  RNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
                DSG YT  A N  G   +T  +K+ D+
Sbjct: 20286 NRKDSGDYTITAENSSGSKSATIKLKVLDK 20315



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/69 (31%), Positives = 34/69 (49%)

Query: 936   IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             IG  T  V W KD  P++ ++R+          LTIK     D GHY  +  N+ G+A  
Sbjct: 23099 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 23158

Query: 996   SANLTIVTK 1004
             + N+ ++ K
Sbjct: 23159 TLNVIVLDK 23167



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 1707  ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
             +T  P   +P     +   +    E  +I  G P+  + W+++G P++ + R+       
Sbjct: 25235 LTIQPSLKLPFNTYSIQAGEDLKIEIPVI--GRPRPNISWVKDGEPLKQTTRVNVEETAT 25292

Query: 1767  YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                L++K  N +D G YT  A N  G A  + ++ V  K
Sbjct: 25293 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 25331



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/84 (29%), Positives = 38/84 (45%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P +  P     V   + ++      G+P  TV W K  + +K +    +S +    +L I
Sbjct: 26322 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 26381

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVTV 4706
              EA  ED G Y+    NSAG +TV
Sbjct: 26382 KEASKEDVGTYELCVSNSAGSITV 26405



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 21/70 (30%), Positives = 34/70 (48%)

Query: 4637  GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
             G  +       GKP P++ W K    +K S++ + S+T ++ TL I  A  E  G Y  +
Sbjct: 28505 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 28564

Query: 4697  AYNSAGRVTV 4706
               N+  R+ V
Sbjct: 28565 LDNAVCRIAV 28574



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDF--G 3613
            P FT     +++ E S+A FE  +   PV +    V WF +G+ + T +       F  G
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQISFSDG 61

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
               L I  V + ++G Y+ KATN  G+AT + +L VK
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVS 130
            P+F +  KN    +G   + + +  GNP P + W  K + ++  +KY  +R     G+ +
Sbjct: 1556 PMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWL-KNSDIIVPHKYPKIRIEGTKGEAA 1614

Query: 131  LLIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPE 164
            L I      D   YT TA N+ G     C V ++ E
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 2/101 (1%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP FV ++  +  +  G++A   C+++    P +++ ++ N K L  +    + F     
Sbjct: 4663 PPSFVKKVDPSYLMLPGESARLHCKLKG--SPVIQVTWFKNNKELSESNTVRMYFVNSEA 4720

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSII 2341
             LDI     ED+G YS +A+N +G  + +  + +    S I
Sbjct: 4721 ILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFI 4761



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 2/100 (2%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            +S  +P  +   +    V++G    L+ +    G   +  +WF +G+ +T+GS++K    
Sbjct: 5500 LSVKEPATITEEAVSIDVTQGDPATLQVKFS--GTKEITAKWFKDGQELTLGSKYKISVT 5557

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
                 L II     D+GEYT    N +G +   A + V++
Sbjct: 5558 DTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLD 5597



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 20/61 (32%), Positives = 34/61 (55%)

Query: 2141 LTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
            +TI WF + +++ +G       D    +L++    A DSGTY+C+ +N +G A +  TL 
Sbjct: 5724 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 5783

Query: 2201 V 2201
            V
Sbjct: 5784 V 5784



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/94 (23%), Positives = 42/94 (44%), Gaps = 2/94 (2%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            Q P  + +      + E +    EC +A  G P +KV+W  +GK ++    F+  ++   
Sbjct: 6065 QEPAQIVEKAKSVDVTEKDPMTLECVVA--GTPELKVKWLKDGKQIVPSRYFSMSFENNV 6122

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064
             +     V  +DSG+Y  +  N +G     A ++
Sbjct: 6123 ASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLR 6156



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 20/63 (31%), Positives = 31/63 (49%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P ++V+W KDG+ I  S   +  F     S  I  +  +D+G YT +  N  G +   A 
Sbjct: 6095 PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 6154

Query: 860  IRV 862
            +RV
Sbjct: 6155 LRV 6157



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 2/109 (1%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P  T  L  ++   G   H E ++       +  +W+ + K + + +++    +   V+L
Sbjct: 6164 PSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSL 6221

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALP 1686
            ++ +   ED+  YTC+  N  G+   SGI  V    S  ++   + A+P
Sbjct: 6222 EVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIP 6270



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F + L     +  G  +  E ++   G P +R  W+ N  EL    ++R T     
Sbjct: 6348 EPPKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDSV 6405

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
              + +N++   D+G ++C+A N AG
Sbjct: 6406 AVIQMNNLSTEDSGDFICEAQNPAG 6430



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FV+    P  V  GKN+     +   G P  +V WF   R +  G R   Y++     
Sbjct: 6820 PSFVKE-PEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 6876

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSA 1261
            L++ +   + +GEYT    N+ G A
Sbjct: 6877 LELFNIDISQSGEYTCVVSNNAGQA 6901



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 3/115 (2%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            Q  P F   LK  ++ V G  V L  ++       +++ W+++GV L     L+++F   
Sbjct: 7099 QLPPSFARQLKDIEQTV-GLPVTLTCRLNGSAP--IQVCWYRDGVLLRDDENLQTSFVDN 7155

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRI 2753
            + TL I       SG Y+C A+N LG A S+A +   +        + P S+D I
Sbjct: 7156 VATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVI 7210



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 2/91 (2%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P+++  + A     +G+ + LE ++     P++K+ W+ N   L +  ++ ++       
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSVAL 7348

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            L + +    DSG Y C+A+N  G+A  S+ +
Sbjct: 7349 LTINEASAEDSGDYICEAHNGVGDASCSTAL 7379



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 7/100 (7%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWF--HNGRPFATGSRVHTLNDFG 3751
            PP F +E  ++++   G P    C+V+  G P +RI W+  H     A   ++   N+  
Sbjct: 7946 PPYF-IEPLEHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVA 8002

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791
              +L I+ +   D GEY+C+A N  G+  ++A +    ++
Sbjct: 8003 --SLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERK 8040



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 2/91 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   LK V    G  + FE RI   G   +++ W K+G  ++  +   + F     +
Sbjct: 8042 PPFFARKLKDVHETLGFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHNVAT 8099

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVL 726
            L +L  +    G+Y C A +  G A + A L
Sbjct: 8100 LQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 21/86 (24%), Positives = 45/86 (52%), Gaps = 2/86 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F + L+    +++ +   ++C++   G P +KV W+++E  I++SS+   +    
Sbjct: 8229 QEPPRFIKKLEPSRIVKQDEFTRYECKI--GGSPEIKVLWYKDETEIQESSKFRMSFVDS 8286

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
               + + ++  ED G Y C A N  G
Sbjct: 8287 VAVLEMHNLSVEDSGDYTCEAHNAAG 8312



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            K+  G +   E  V    +L+   +W+ +GK++TS N+ +         L I +V   DS
Sbjct: 8523 KVTTGDTCTLECTVAGTPELS--TKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDS 8580

Query: 1114 GVYTVVARNAAGEAQLSASMTVETRS 1139
            GVY+   +N  G+   +AS+ V  R+
Sbjct: 8581 GVYSFEVQNPVGKDSCTASLQVSDRT 8606



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 3/101 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F V+  D +DV  G  V F   V+  G P   + WF        G R +   +    
Sbjct: 8701 PPSF-VQKPDPMDVLTGTNVTFTSIVK--GTPPFSVSWFKGSSELVPGDRCNVSLEDSVA 8757

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
             L++  +    +GEYTC  +N+ G A+ T  +   A    V
Sbjct: 8758 ELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFV 8798



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            +P +     + + +  G  A  + +L   G   + V W K    +  ++     F     
Sbjct: 8886 EPPYFVKQLEPVKVSVGDSASLQCQLA--GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVA 8943

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
             L    V ++D+G Y C+A N++G+ + S  LT+  +K
Sbjct: 8944 TLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK 8981



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 3/76 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P +   ++  T++E +     C+      P ++ EW+RNG++L    R++T  +     L
Sbjct: 9672 PAWERHLQDVTLKEGQTCTMTCQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHKL 9728

Query: 3890 DILYVYAEDSGEYICR 3905
             I  V AED G+Y C+
Sbjct: 9729 TIADVRAEDQGQYTCK 9744



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 5/123 (4%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            + + QY    +  ET   + I  + +  QF K  Q+  V+E +   F+C V+      VT
Sbjct: 9736 EDQGQYTCKYEDLETSAELRIEAEPI--QFTKRIQNIVVSEHQSATFECEVSFDD-AIVT 9792

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVAR-NKSGETAFQCRLNVI 483
            W+    ++ +   +    N+   H + I NVT  D GV + +AR    GE      L + 
Sbjct: 9793 WYKGPTELTESQKYNFR-NDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLT 9851

Query: 484  EKE 486
             KE
Sbjct: 9852 TKE 9854



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 80/392 (20%), Positives = 151/392 (38%), Gaps = 29/392 (7%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             EF  P++DQ +++EG  A  E     +     +V+W K+G  +  S +     +     L
Sbjct: 13213 EFTKPLEDQ-TVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKL 13268

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRY 1029
              I   T  D   YTC A +      TS NL +V       E   P    +++  E A   
Sbjct: 13269 VIHDCTPEDIKTYTCDAKD----FKTSCNLNVVPPH---VEFLRPLTDLQVREKEMARFE 13321

Query: 1030  SKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSA 1089
              + + E  K+          KG    +  + A     V  +  L    E+    +   ++
Sbjct: 13322 CELSRENAKVKWFKDGAEIKKGKKYDIISKGA-VRILVINKCLLDDEAEYSCEVRTARTS 13380

Query: 1090  NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL----SASMTVET-RSSIDTS 1144
               +    +      ++A++   ++    +V   +   A++         +ET R  I T 
Sbjct: 13381 GMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTE 13440

Query: 1145  SIHRGLYEKTRHIEESKFVE---PMYQIEEISKSKPVFVQPLSNPP--PVSEGKNIHLEC 1199
                R L  +  H+E++       P  + +   K   +  + +S P    + EG+     C
Sbjct: 13441 GRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVC 13500

Query: 1200  RLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLG 1259
              +     P   V+W  + +++  G ++    D     L +  AT  D G Y V     +G
Sbjct: 13501 SISKESFP---VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VG 13553

Query: 1260  SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL 1291
             +A  +A + VIE+  IV   ++ +  EQ +++
Sbjct: 13554 AARAAAHLTVIEKLRIVVPLKDTRVKEQQEVV 13585



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 6/120 (5%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
             E  + IE+ ++ ++P        RD   V  G + R    V+G+P P VTW +N+R +  
Sbjct: 17435 EVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQ 17494

Query: 435   DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             +   +     S   +++I N   S  GV + +A+N++GE      ++V++    V   F+
Sbjct: 17495 EATIETTAISS---SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 17551



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 24/69 (34%), Positives = 33/69 (47%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L+ G   +  V + G P P++TW K    L +    +I +T   T LR  N  K D+G Y
Sbjct: 20632 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 20691

Query: 337   TLLAENPNG 345
              L  EN  G
Sbjct: 20692 ILTLENSCG 20700



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 35/113 (30%), Positives = 51/113 (45%), Gaps = 5/113 (4%)

Query: 235   SFRES-ITKRYVGESDVQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGN 292
             +FR S I    VGE  V    EI +R + P      A+  R   ++ G   +  V + G 
Sbjct: 21672 NFRISAINDAGVGEPAVIPDVEIVEREMAPDFELD-AELRRTLVVRAGLSIRIFVPIKGR 21730

Query: 293   PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             P P VTW K+   L   N+  I  T + T L +    + D+G + +  ENP G
Sbjct: 21731 PAPEVTWTKDNINL--KNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 21781



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/66 (33%), Positives = 32/66 (48%)

Query: 797   VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
             +  PT  V W+KD  P+  ++R+ +        L I     ED G Y V+  N  GEAI 
Sbjct: 23099 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 23158

Query: 857   TASIRV 862
             T ++ V
Sbjct: 23159 TLNVIV 23164



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 21/66 (31%), Positives = 33/66 (50%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G D Q  +   G P P VTW K+ + L +  ++ I  T + + L +    ++D+G Y L 
Sbjct: 28213 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 28272

Query: 340   AENPNG 345
              EN  G
Sbjct: 28273 IENGVG 28278



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-- 3475
            +AP FT PL ++  L EG  A FEA ++    P  +V W+ +G+ +   +       F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            G   L I      +SG Y  +A N  G+A +TA + V+ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GF 3752
            P FT  ++ ++ V EG    F+  +   G P   + WF +G+  +T +       F  G 
Sbjct: 6    PTFTQPLQ-SVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L I  +   ++G Y+ +ATN  G AT+TA++   A+
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 3/153 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T E +V+   A  PP FV    ++TV +G   R   RVTG P P V +  +G  I +   
Sbjct: 92   TAELLVKAETA--PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 4157 YKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
            ++++ +G +Y   I +    D+G   V              L V    +      K    
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVID 4248
                  ++  R E ++E  F+ R +   + VID
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVID 242



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F+ ++Q +T + +G     + R+  +  P +K  ++ +G ++     ++   +  + 
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLY 159

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             L I   Y E+SG Y   ATN +GR ++ A L    +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 4/125 (3%)

Query: 1147 HRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGD 1206
            H+G Y     + +S       ++  + ++ PV  + +  P  V+ G      C ++    
Sbjct: 4354 HQGEYV-CEALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSA-- 4409

Query: 1207 PTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
            P +R +WF  GR +    +          +L+I+     D GEYT +A N  GS   +A 
Sbjct: 4410 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 4469

Query: 1267 VRVIE 1271
            + V E
Sbjct: 4470 LTVTE 4474



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            L D+ K    +    V   APV    ++ + VA    A F   +     P +R +W + G
Sbjct: 4363 LNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAG 4420

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
              I  S++ +        +L +      D G YTC+A NE G    ++TL V
Sbjct: 4421 REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4472



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1974 VVEKPQFGKPIKNAE---VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY 2030
            +V++P   K I+ AE   VT G P  LE T+     P ++ +WY +GRP+    +++ ++
Sbjct: 4939 IVKEP--AKIIERAELIQVTAGDPATLEYTVA--GTPELKPKWYKDGRPLVASKKYRISF 4994

Query: 2031 DFGYVALDILYAYAEDTGTYMCKATNAVGEA 2061
                  L    A   D+G Y  + +N VG +
Sbjct: 4995 KNNVAQLKFYSAELHDSGQYTFEISNEVGSS 5025



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 2/87 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EP  F+ +++    L +G +     ++     P +K+ WF N +++    ++R       
Sbjct: 5224 EPATFVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVEST 5281

Query: 3340 VILDILYCYEENSGEYECVATNKLGRD 3366
             +L +     E+SGEY C A N+ G D
Sbjct: 5282 AVLRLTDVGIEDSGEYMCEAQNEAGSD 5308



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 21/61 (34%), Positives = 33/61 (54%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P +KI W+ N + +++ S+ +++       L L DV   DSG Y C+A N+ G    SS 
Sbjct: 5254 PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSI 5313

Query: 3001 V 3001
            V
Sbjct: 5314 V 5314



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 49/281 (17%), Positives = 96/281 (34%), Gaps = 15/281 (5%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            QG  A  + K  G       W +    L   +KY +   +    + ++  +    D GEY
Sbjct: 5519 QGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTE--KKDSGEY 5576

Query: 145  TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET---VEHKAYGTQGYTTEQS 201
            T   +N  G + C   I                    +  +   +E    G+   + +  
Sbjct: 5577 TFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWF 5636

Query: 202  RQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITK-RYVGESDVQIS-TEIDRS 259
            +  Q++        S+++ +K    +     E+S  E      Y   +  +    +    
Sbjct: 5637 KDDQEI--------SASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGH 5688

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            L    PP   +KP++  +      Q +  + G     + WFK+ + L +     +     
Sbjct: 5689 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDT 5748

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             T+L +   + +DSG Y     N  G   +   L V+ P +
Sbjct: 5749 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQ 5789



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 5/96 (5%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP FI +++ V ++V+      E  +     P  +V W  N +++    +Y       +
Sbjct: 5880 EPPTFIRELKPV-EVVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTLTDRVSV 5936

Query: 3340 VILDILYCYEENSGEYECVATNKLG--RDSTKANLK 3373
              L I  C   ++GEY+C+ +N+ G    ST+  LK
Sbjct: 5937 FNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 5972



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            VQ+        KS D + E   + LE  V     P LK++W K+G  +        +F+ 
Sbjct: 6064 VQEPAQIVEKAKSVD-VTEKDPMTLECVVAGT--PELKVKWLKDGKQIVPSRYFSMSFEN 6120

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
             + +  I S+   DSG YT K  N  G +   A +++ D++
Sbjct: 6121 NVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQN 6161



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 3/98 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ PIF       + L +G  V+LE +++    P   + W+K+   L +G + K   + 
Sbjct: 8322 VKEPPIFRKKPHPIETL-KGADVHLECELQGT--PPFHVSWYKDKRELRSGKKYKIMSEN 8378

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             L ++ I ++   D G Y CKATN +G      SI ++
Sbjct: 8379 FLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 8416



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 3/99 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K+ P F   L+ P     G++   EC +   G   ++V W  + R +  G +++  Y   
Sbjct: 9077 KNPPFFDIRLA-PVDAVVGESADFECHVT--GTQPIKVSWAKDSREIRSGGKYQISYLEN 9133

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
               L ++     D+G+YT  AVN +G    +A + + ER
Sbjct: 9134 SAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 9172



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 65/276 (23%), Positives = 109/276 (39%), Gaps = 31/276 (11%)

Query: 4217  WYDETTQYQRTETELEKTFEERQVLQRQGVI---DHR-------PELK----PKVIKEPE 4262
             +Y+    Y   E E E+ ++ER+V+Q Q  +    H        PE K    PKVIK+P 
Sbjct: 10053 YYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPV 10112

Query: 4263  TEWQQSVKRKKNEE--YYNKLQELENEQV-IKESR--LRESTHQYAIPGDKVTSNTVAKS 4317
              E  +   R+  EE     K+ E+  + V  K SR  ++E   +  +P    T   V   
Sbjct: 10113 IEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVH-TKKMVISE 10171

Query: 4318  MAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKE 4377
                 +  + ++   VT   VQK++  + +I       V          ++   E V    
Sbjct: 10172 EKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAVSKRVEPPPKVPELPEKPAPEEVAPVP 10231

Query: 4378  ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFE-HEQARFEVEFDG 4436
             I +K        +E  A     V + PV   K P+   K +P    +  E  +  V  + 
Sbjct: 10232 IPKK--------VEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEK 10283

Query: 4437  EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
              P+P+ K  ++  P    P+ Q    + + I I+ Q
Sbjct: 10284 IPVPVAK--KKEAPPAKVPEVQKRVVTEEKITIVTQ 10317



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             V  G+ I +  R++  G P   + W   G+ +    R     D   V L I  A  AD G
Sbjct: 18847 VRVGQTIRILARVK--GRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 18904

Query: 1249  EYTVRAVNHLGSAHTSAIVRVIER 1272
             +Y + A N  G A  SAIV V++R
Sbjct: 18905 KYIISAKNSSGHAQGSAIVNVLDR 18928



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 6/101 (5%)

Query: 2640  QAPIFTTHLKSYDKLV--EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-D 2696
             +AP     +K  D ++   G+   LEA V  R  P +  EW K+G  L   A+L+    D
Sbjct: 22384 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTM--EWSKDGKELEGTAKLEIKIAD 22441

Query: 2697  FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             F    ++ +S R D SG YT  ATN  G A    ++K+ DR
Sbjct: 22442 FSTNLVNKDSTRRD-SGAYTLTATNPGGFAKHIFNVKVLDR 22481



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F     + +  +G  A+F+ K+ G P P   W      +V    + +   E  G  SL
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED-GTQSL 1515

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            +I    P D GE+T  A+N+ G +  SV +  E
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1548



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 87/362 (24%), Positives = 150/362 (41%), Gaps = 45/362 (12%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            +P  + +  S + V EG  V  E K   V+  +++  W K+GQ V    R   + D    
Sbjct: 2354 RPIAILQGLSDQKVCEGDIVQLEVK---VSLESVEGVWMKDGQEVQPSDRVHIVIDKQSH 2410

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L I D+  ED+G Y+   +  +G    S R++  S  D++        L+ + V+E   
Sbjct: 2411 MLLIEDMTKEDAGNYSF-TIPALGLS-TSGRVSVYSV-DVITP------LKDVNVIEG-- 2459

Query: 1563 KYHRTDMVDEVTTQAPICTTS---LKNVEIKEGQRAHFERRLIPVSDATLKVEWYH--NN 1617
                T  V E     P  T+    L + +IK   R    + ++  +   L +   H  + 
Sbjct: 2460 ----TKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVINRTHASDE 2512

Query: 1618 KPLKSGSRFTETN-NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS----- 1671
             P K      ETN N     + I+  L + + T T   +  + E   SGI ++ +     
Sbjct: 2513 GPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV-ELSHSGIDVLWNFKDKE 2571

Query: 1672 -KKSIYLESQHEGALPRLNQL----EDTSKYQRHSAQD----EVITQAPVFTMPMKDIRV 1722
             K S   + +  G + +L  L    +D  KY  ++ ++    ++       + P+ D  V
Sbjct: 2572 IKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVAGGAISKPLTDQTV 2631

Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782
            AE+Q A FE     V +P  + EWLR+G  +  +N + +  D     L +     +D G 
Sbjct: 2632 AESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2688

Query: 1783 YT 1784
            YT
Sbjct: 2689 YT 2690



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYIS-LDMLSLNIQDSGEYTCRAVSATGVAETKA 724
            P ++ +W K G+ I  S +  SI    YIS L++L   + D GEYTC+A +  G     A
Sbjct: 4410 PNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 4468

Query: 725  VLHVT 729
             L VT
Sbjct: 4469 TLTVT 4473



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/99 (24%), Positives = 48/99 (48%), Gaps = 2/99 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F   +     ++ G+   L  ++  +  P +++ WFKN   L+    ++  F  
Sbjct: 4660 VREPPSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVN 4717

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                L I  ++ +DSG Y+C+A N +G    +  I I++
Sbjct: 4718 SEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE 4756



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/121 (21%), Positives = 52/121 (42%), Gaps = 2/121 (1%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P ++  +   + ++ G+   L  ++  K  P +++ W+ N K L + +  ++        
Sbjct: 4664 PSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 4721

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLED 3030
            LD+ DV   DSG Y+C+A N  G    S+ +      + I+  +      G   +   E 
Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEV 4781

Query: 3031 S 3031
            S
Sbjct: 4782 S 4782



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 4/93 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  +     +  G+ A   C+++    P + + WF N +++   +  R         
Sbjct: 4664 PSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 4721

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            LDI     EDSG+Y C+A N +G   ++C+ ++
Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVGS--DSCSTEI 4752



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L+ +D+I+ G     +C  I  G   + ++WF++++ I  S +   +       
Sbjct: 5602 PSFTKKLKKMDSIK-GSFIDLEC--IVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + IS +   D G Y C A+N  G
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAG 5681



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P F     + +    T V L+  +   G   M ++WF + K + +G   R  ++
Sbjct: 5689 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVG--GTAPMTIKWFKDNKELHSGAA-RSVWK 5745

Query: 1365 FDY-VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             D   +L+L +    DSG Y CQ +N +G A +   L V
Sbjct: 5746 DDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFV 5784



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 21/59 (35%), Positives = 32/59 (54%)

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            + I+WF +NK L SG       D +  SL++      DSG Y C+ +N  G+AT+  +L
Sbjct: 5724 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATL 5782



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/113 (23%), Positives = 50/113 (44%), Gaps = 2/113 (1%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P F++  S    +  G++   EC++   G P +RV W+ +G  +T   +    +  G
Sbjct: 5785 KEPPQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDG 5842

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286
                 I  A   ++G Y   A N  G+A  S  ++V E    + + +  + ++
Sbjct: 5843 LATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVK 5895



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 2/104 (1%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P+F       + ++ G    FE ++   G   +RV W  DG  + A  +    F  G 
Sbjct: 5786 EPPQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGL 5843

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                I    V ++G Y C A N  G A+ S  L +      I E
Sbjct: 5844 ATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE 5887



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F +  +    L  GQ   +E ++   G P +R  WY++G E+    +   +   G 
Sbjct: 5786 EPPQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGL 5843

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             T  I+     ++G Y+C+A N AG
Sbjct: 5844 ATFQISGARVENSGTYVCEARNDAG 5868



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L  +E +K  D    EC V     P   + W  N ++IR+  +Y  T       
Sbjct: 5882 PTFIRELKPVEVVKYSD-VELECEVT--GTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN 5938

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
            L I      D+G Y C  +N+ G    +C+ +VA
Sbjct: 5939 LHITKCDPSDTGEYQCIVSNEGGSC--SCSTRVA 5970



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 3/112 (2%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFG 1900
            N  P F  +L    K+  G S H EC++       +  +W+ +GK + +  +YR      
Sbjct: 6161 NIPPSFTKKLTKMDKVL-GSSIHMECKVSG--SLPISAQWFKDGKEISTSAKYRLVCHER 6217

Query: 1901 FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952
              +L++  +  ED+  YTCK  N  G    S  L V+   S +     + A+
Sbjct: 6218 SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAI 6269



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 5/100 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTE-GHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P+F K ++ +++ + G    LE  +     P +RV W+ N   +    +++ T+  
Sbjct: 6346 VTEPPKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFID 6403

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
                + +     ED+G ++C+A N  G   T+ S KV  K
Sbjct: 6404 SVAVIQMNNLSTEDSGDFICEAQNPAGS--TSCSTKVIVK 6441



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 4/109 (3%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            T+ P+F   ++    +K G  +  E ++   G   +RV W ++   + AS +    F   
Sbjct: 6347 TEPPKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDS 6404

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014
               + + +++  D+G + C A N  G  +TS +  ++ K+  +  S  P
Sbjct: 6405 VAVIQMNNLSTEDSGDFICEAQNPAG--STSCSTKVIVKEPPVFSSFPP 6451



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F       E  +   V LE  L+    P   V WY + R ++   ++K      
Sbjct: 6440 VKEPPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNF 6497

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            + ++ IL     D G Y CKA N VG      +VK+
Sbjct: 6498 HTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL 6533



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 3/109 (2%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D+  PP F  ++++ T  V   +   EC++A  G   + V WF     ++   ++   + 
Sbjct: 6722 DRAVPPSFTRRLKN-TGGVLGASCILECKVA--GSSPISVAWFHEKTKIVSGAKYQTTFS 6778

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQ 4076
                 +    +   D G Y C A N+ G DE +AV+     P  V + +
Sbjct: 6779 DNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 6827



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F   L  P E   G     + +V   G P +   WY    +L+    +RT      
Sbjct: 7004 EPPYFVTELE-PLEAAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTNNV 7060

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             TL  N V  ND+G Y CKA N  G
Sbjct: 7061 ATLVFNKVNINDSGEYTCKAENSIG 7085



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G++  FEC+V  ++   ++I W  +NK +  G  Y  T   +   L I    + DSG YT
Sbjct: 7212 GESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYT 7269

Query: 2848 CKATNSKGSATTSGSL 2863
            C+ATN  G    S  L
Sbjct: 7270 CQATNDVGKDMCSAQL 7285



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 20/66 (30%), Positives = 35/66 (53%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P L  +WFK+G  L+  ++   TF   + +L I      D G+Y+ +  N +G++  T S
Sbjct: 7599 PELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVS 7658

Query: 2732 IKIEDR 2737
            + + DR
Sbjct: 7659 VHVSDR 7664



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P FIR L+D+  +  G +   E +++  S P + V W++DG  I +  +  S F+    +
Sbjct: 7668 PSFIRKLKDVNAIL-GASVVLECRVSG-SAP-ISVGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            LN+  L   D G YT  A N  G    +A + V
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 7757



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L  +E +  G+ A  +C+V+    P + I W+    K+R+   Y+        +
Sbjct: 7947 PYFIEPLEHVEAVI-GEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVAS 8003

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L I      D G Y CKA N +G   ++  L +
Sbjct: 8004 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVI 8036



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 3/91 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F R L+D+ E   G    FE ++   S+P ++V WYKDG  +   + + + F     +
Sbjct: 8043 PFFARKLKDVHETL-GFPVAFECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVAT 8099

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            L I+       G Y   A N LG A S+A +
Sbjct: 8100 LQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +K+   T G PV  E  +   ++P ++V WY +G  ++     +T++      L
Sbjct: 8043 PFFARKLKDVHETLGFPVAFECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVATL 8100

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067
             IL       G Y C A+N +G A +++ +
Sbjct: 8101 QILQTDQSHIGQYNCSASNPLGTASSSAKL 8130



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 2/107 (1%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+  +T S   P  I +  +  K+  G +   E  +     P+L  +WF +GK+L   ++
Sbjct: 8501 QECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGT--PELSTKWFKDGKELTSDNK 8558

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
            Y+      +  L I+     +SG Y     N +G+DS  A+L+ + +
Sbjct: 8559 YKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 8605



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 6/111 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP F  +L+ T  +  G +   EC+V     P + + ++H G  + S  ++  T      
Sbjct: 8608 PPSFTRKLKETNGL-SGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTC 8664

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
            +L +      D+G+Y+  A N  G    +  +TV    S +   Q+P+ ++
Sbjct: 8665 ALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV---QKPDPMD 8712



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            +PP FV Q++     V  ++   +CQLA  G P + V W+     L     +   +    
Sbjct: 8886 EPPYFVKQLEPVKVSVG-DSASLQCQLA--GTPEIGVSWYKGDTKLRPTTTYKMHFRNNV 8942

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYG 4055
              + F  V   DSGEY+C+A N  G
Sbjct: 8943 ATLVFNQVDINDSGEYICKAENSVG 8967



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FV+ L  P  VS G +  L+C+L   G P + V W+     +   + +K ++      
Sbjct: 8888 PYFVKQLE-PVKVSVGDSASLQCQLA--GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVAT 8944

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            L        D+GEY  +A N +G    S  + V E+
Sbjct: 8945 LVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 8980



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            E  NPP F + +   +D   G    F+C V   G   +++ W  + R   +G +      
Sbjct: 9075 EGKNPPFFDIRLAP-VDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYL 9131

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                 L +  +   D+G+YTC A N+ G  + TA++
Sbjct: 9132 ENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL 9167



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 2/91 (2%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F + L +  E  EG +   E ++   S P + V WYK+   I  +S     F    + 
Sbjct: 9176 PSFTKRLSETVEETEGNSFKLEGRVAG-SQP-ITVAWYKNNIEIQPTSNCEITFKNNTLV 9233

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            L +      DAG YT +  N  G A+ T+SI
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSI 9264



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 7/84 (8%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491
            L+EG+      + +    PN+K EW+ NG+ LK   R +T  +     L I+    ED G
Sbjct: 9683 LKEGQTCTMTCQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQG 9739

Query: 3492 EYLCRAYNNYGEAVTTASMKVQGK 3515
            +Y C+    Y +  T+A ++++ +
Sbjct: 9740 QYTCK----YEDLETSAELRIEAE 9759



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 76/367 (20%), Positives = 143/367 (38%), Gaps = 39/367 (10%)

Query: 1706  VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
             V+   P FT  ++D    E      +  +     P   V+W ++G  I+ S       D 
Sbjct: 12940 VLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKADG 12996

Query: 1766  GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
                 L +K     D G YTC    + G   TS  L ++ +     E +    L  ++ +E
Sbjct: 12997 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR-----EIKLVRPLHSVEVME 13047

Query: 1826  -DSSRYQRR-EDVEVAVNQAPRFITQLNGPT-KLSEGQSAH----YECRIEPYPDPNMRV 1878
              +++R++    + ++  N   +    L  P  ++ E    H    + CR++     + + 
Sbjct: 13048 TETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQA 13107

Query: 1879  EWYFNGKVLQSGHRYRTSNDFGFAA-LDILTVYGEDSGEYTCK-AINNLGQAVSSIRLNV 1936
                    V  S H        G    L  +TV   ++  + C+ +  ++          +
Sbjct: 13108 -----ANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKL 13162

Query: 1937  QSKESIIRDSQ---HESALEKIQYLEDDSRYKRAVQD-----DSFVVEKP-QFGKPIKNA 1987
             +  + ++  S+   H   L  ++ LED    +   +D     + FV E P +F KP+++ 
Sbjct: 13163 EPSDKVVPRSEGKVHTLTLRDVK-LEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQ 13221

Query: 1988  EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
              V EG    LE  ++  N    +V+W+ NG  + +  +++   D     L I     ED 
Sbjct: 13222 TVEEGATAVLECEVSREN---AKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDI 13278

Query: 2048  GTYMCKA 2054
              TY C A
Sbjct: 13279 KTYTCDA 13285



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/66 (25%), Positives = 34/66 (51%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G   +   ++ G P P +TW K G+ L+   + ++I       L+++   ++D G Y + 
Sbjct: 18850 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 18909

Query: 340   AENPNG 345
             A+N +G
Sbjct: 18910 AKNSSG 18915



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 21/69 (30%), Positives = 35/69 (50%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G +      + G P P V+W K+G  L  +   ++    N  TL + +  + DSG Y
Sbjct: 20234 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 20293

Query: 337   TLLAENPNG 345
             T+ AEN +G
Sbjct: 20294 TITAENSSG 20302



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 4/108 (3%)

Query: 467   ARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLN--VREGEPVVLNARAVGTPTPRIT 523
             A N++GE      + V+ ++ VVAP   ++    L    +E     L     G P P ++
Sbjct: 20884 AENENGEGT-PSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 20942

Query: 524   WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             W+K   P+  +  + + +    +TL +   + SDA  Y  T +NVAG+
Sbjct: 20943 WKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGT 20990



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/82 (29%), Positives = 37/82 (45%)

Query: 4512  VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
             + PS  L     NV + + +++D    G     V W K+G+ ++   R  +       +L
Sbjct: 26320 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL 26379

Query: 4572  LILEAYPQDSGKYECVAINSAG 4593
              I EA  +D G YE    NSAG
Sbjct: 26380 SIKEASKEDVGTYELCVSNSAG 26401



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F   ++ ++ V +G  V    RV   G PT  + ++ +G    +        +    
Sbjct: 103  PPNFVQRLQ-SMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            +L I   Y  D+G Y+  ATN  G AT+TA++    + ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FVQ L +   V +G  + L+ R+   G PT  V+++ +G  +     F+   +    +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I  A   D+G Y+V A N +G A TS    +++  + V   + +  +   Q+ E    
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRA-TSTAELLVQGEEEVPAKKTKTIVSTAQISESRQT 219

Query: 1297 RTKQ 1300
            R ++
Sbjct: 220  RIEK 223



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 1/96 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  P  F+  L+    ++ G    +   +  G P +KI W  N + I+ SS+    F   
Sbjct: 5222 VKEPATFVEKLEPSQLLKKGDAT-QLACKVTGTPPIKITWFANDREIKESSKHRMSFVES 5280

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
               L +  + I+DSGEY C A +  G     +++ V
Sbjct: 5281 TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV 5316



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 15/152 (9%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P  F  +++ +  + +G      C+V   G P ++I WF N R     S+ H ++     
Sbjct: 5225 PATFVEKLEPSQLLKKGDATQLACKV--TGTPPIKITWFANDREIKESSK-HRMSFVEST 5281

Query: 3754 A-LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
            A L +  +   D+GEY C A N+ GS        CS+   IV+  + P     ++ K +E
Sbjct: 5282 AVLRLTDVGIEDSGEYMCEAQNEAGSD------HCSS---IVIVKESP--YFTKEFKPIE 5330

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEES 3844
              +  D      +  TPP  IT  K +T+  S
Sbjct: 5331 VLKEYDVMLLAEVAGTPPFEITWFKDNTILRS 5362



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%)

Query: 1007 IIAESQHPGGLEKIQYLEDASRYSKRTEEEV-KITQKPRFLGPLKGTNKIVEGQSAHFEA 1065
            II+  +   G    +   D  R S +    V  +   P F   LK  + I +G     E 
Sbjct: 5565 IISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSI-KGSFIDLEC 5623

Query: 1066 RVEPQSDLTMTVEWYFNGKQITSANRIQ-TYHDFGYVALDIASVRAEDSGVYTVVARNAA 1124
             V     ++  ++W+ + ++I+++ + + ++HD     L+I+ +   DSG YT  A N A
Sbjct: 5624 IVAGSHPIS--IQWFKDDQEISASEKYKFSFHD-NTAFLEISQLEGTDSGTYTCSATNKA 5680

Query: 1125 GEAQLSASMTVE 1136
            G  Q S  +TV+
Sbjct: 5681 GHNQCSGHLTVK 5692



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 3/84 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F + L  + ++  G + H E +++  S P +  +W+KDG+ I+ S++   + +   VS
Sbjct: 6164 PSFTKKLTKMDKVL-GSSIHMECKVSG-SLP-ISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGE 853
            L + +L  ED  +YT +  N  G+
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAGD 6244



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/78 (28%), Positives = 42/78 (53%), Gaps = 2/78 (2%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G    LEC++   G   + VEW+ +GK + +  + + ++     +L +LSV  +D+G YT
Sbjct: 6645 GETCTLECKV--AGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 6702

Query: 1385 CQATNQLGEAVTSCALRV 1402
             Q  N +G++  +  + V
Sbjct: 6703 FQVQNNVGKSSCTAVVDV 6720



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            A PP F  ++++ T  V G S   E ++       + V WF+   K+  G +Y+T     
Sbjct: 6724 AVPPSFTRRLKN-TGGVLGASCILECKVA--GSSPISVAWFHEKTKIVSGAKYQTTFSDN 6780

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            +  L +      + G Y CVA N  G D  +A L
Sbjct: 6781 VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVL 6814



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/76 (28%), Positives = 35/76 (46%)

Query: 790  FEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVN 849
            F  +      P +  +W+KDGR ++A S+    F     SL I      D G Y+    N
Sbjct: 7589 FALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKN 7648

Query: 850  KLGEAISTASIRVAAR 865
             +G++  T S+ V+ R
Sbjct: 7649 SVGKSNCTVSVHVSDR 7664



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 5/93 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH-TLNDFGF 3752
            PP F  +  D+++V  G  + F   +   G P  ++ WF   R    G   + +L DF  
Sbjct: 7760 PPSFE-QTPDSVEVLPGMSLTFTSVIR--GTPPFKVKWFKGSRELVPGESCNISLEDF-V 7815

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
              L++  +   ++G+Y+C  TN  GSA+ T  +
Sbjct: 7816 TELELFEVQPLESGDYSCLVTNDAGSASCTTHL 7848



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 19/99 (19%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F  P++ +     + A  + ++   G P++R+ W +    + ++          
Sbjct: 7943 VLEPPYFIEPLEHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNN 8000

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
              +L +  V+  D G Y+C+A N +G   +S+ L ++ +
Sbjct: 8001 VASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKER 8039



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 3/99 (3%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F  P+ + +    G  A  + +++  G   +R+ W K+   + ++      F    
Sbjct: 7945 EPPYFIEPL-EHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNV 8001

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
             +L I  V   D G Y+C+A N++G   +SA L I  +K
Sbjct: 8002 ASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERK 8040



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F +PL++++ +  G+ A   C++   G P +++ W++    +  +            S
Sbjct: 7947 PYFIEPLEHVEAVI-GEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVAS 8003

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+ V   D G Y C+A N +G
Sbjct: 8004 LVINKVDHSDVGEYSCKADNSVG 8026



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +KD+         FE R+   G   L+V W ++GV ++    L T        L
Sbjct: 8043 PFFARKLKDVHETLGFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHNVATL 8100

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             +   +    G Y C A N LG A +S+ L +
Sbjct: 8101 QILQTDQSHIGQYNCSASNPLGTASSSAKLIL 8132



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 33/148 (22%), Positives = 64/148 (43%), Gaps = 4/148 (2%)

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQ--APRFITQLNGPTKL 1856
            T FV + A+LQ+    +S + +      +         ++ +++   P F         L
Sbjct: 8091 TSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDL 8150

Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGE 1916
            + G+S  ++C +       +++ W  + + ++ G  Y+ +     A L +L V   D+G+
Sbjct: 8151 ALGESGTFKCHVTGTAP--IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQ 8208

Query: 1917 YTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            YTC A N  G+   S  L VQ     I+
Sbjct: 8209 YTCYASNIAGKDSCSAHLGVQEPPRFIK 8236



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 8/107 (7%)

Query: 1967 AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF 2026
            +V + + +VEKP+      + +VT G    LE T+     P +  +W+ +G+ +   +++
Sbjct: 8508 SVLEPATIVEKPE------SIKVTTGDTCTLECTVA--GTPELSTKWFKDGKELTSDNKY 8559

Query: 2027 KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
            K ++      L I+     D+G Y  +  N VG+   T+S++V  ++
Sbjct: 8560 KISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT 8606



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P FT+ L   + L  G     E +V   G P +   W+  G E+  G +++TT       
Sbjct: 8609 PSFTRKLKETNGL-SGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 8665

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
            L +N +  +D+G Y C A N AG
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAG 8688



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 9/138 (6%)

Query: 3941 EALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPV 4000
            E + + E ++ + ++  +LT  +     +K PP F  Q++     V +    F+C ++  
Sbjct: 8957 EYICKAENSVGEVSASTFLTVQE-----QKLPPSFSRQLRDVQETVGLPVV-FDCAIS-- 9008

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
            G   + V W+ +GKPL         +      +N        +G+Y C ATN  G   + 
Sbjct: 9009 GSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSS 9068

Query: 4061 A-VIKTTGKPGIVYDSQL 4077
            A +I T GK    +D +L
Sbjct: 9069 ARLILTEGKNPPFFDIRL 9086



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 2/81 (2%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G +A FE  +T      ++V W KD R I +  +    +      L ++ +   D+G YT
Sbjct: 9094 GESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYT 9151

Query: 845  VRAVNKLGEAISTASIRVAAR 865
              AVN++G+   TA + +  R
Sbjct: 9152 CYAVNEVGKDSCTAQLNIKER 9172



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 42/183 (22%), Positives = 73/183 (39%), Gaps = 13/183 (7%)

Query: 4622  PPEIIEPLKDKIVAE----GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
             P + ++ +KD I+ E    G +  F C +V        W K    I+ S   +      +
Sbjct: 12041 PLKFVKEIKDIILTESEFVGSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRFIADGKD 12099

Query: 4678  YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
               L I +    D G+Y CV        T  AKL V   ++       T   ++ V +GQP
Sbjct: 12100 RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV---EELPVRFVKTLEEEVTVVKGQP 12156

Query: 4738  AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE--GNNAVLLIGNTYEEDTGTFTCRA 4795
                  ++    +  + W ++G ++ E P  +++    G    L I +  + D GT+T   
Sbjct: 12157 LYLSCELNK--ERDVVWRKDGKIVVEKPG-RIVPGVIGLMRALTINDADDTDAGTYTVTV 12213

Query: 4796  TTA 4798
               A
Sbjct: 12214 ENA 12216



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 25/77 (32%), Positives = 36/77 (46%)

Query: 494   VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
             V+  + L V+ G  + L A   G P P+ITW K  + +  +  + I      ST+ I  +
Sbjct: 14621 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS 14680

Query: 554   KASDAAWYQCTAQNVAG 570
             K SD   Y   A NV G
Sbjct: 14681 KRSDTGTYIIEAVNVCG 14697



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 5/106 (4%)

Query: 4511  IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             ++PP+F L      V +G+ +++D    G     V W K+   ++   R      +    
Sbjct: 23072 VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSL 23131

Query: 4571  LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
             L I +A  +D G Y     NSAGEA      +V      DKP P T
Sbjct: 23132 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV-----LDKPGPPT 23172



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGYVALDIASVRAED 1112
            +I+EG    F  ++         + WY +GK+I    R Q  +   G  +L I  V  ED
Sbjct: 1301 RILEGMGVTFHCKMSGYP--LPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358

Query: 1113 SGVYTVVARNAAGEAQLSASMTVE 1136
             G+YT  A N  G A  S  + VE
Sbjct: 1359 EGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF-NFGYVSLNIMHLRAEDAGS 842
            EG    F  +++    P  ++ WYKDG+ I    R    F   G  SL I  +  ED G 
Sbjct: 1304 EGMGVTFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361

Query: 843  YTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
            YT  A N  G AI +  + V   + + A   IP
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP 1394



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 3/87 (3%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V   Q   F  +L       +   A +EC      +P ++V+WY +G  +  G +YR  +
Sbjct: 2168 VQAKQLITFTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHS 2224

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINN 1924
            D     L ILT+   D+ +Y+C  + +
Sbjct: 2225 DRKVHFLSILTIDTSDAEDYSCVLVED 2251



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F + +K  EV +   V LE  +T    P   V W  N R ++   ++  T    
Sbjct: 5878 VKEPPTFIRELKPVEVVKYSDVELECEVT--GTPPFEVTWLKNNREIRSSKKYTLTDRVS 5935

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067
               L I      DTG Y C  +N  G    ++ V
Sbjct: 5936 VFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRV 5969



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/109 (23%), Positives = 43/109 (39%), Gaps = 3/109 (2%)

Query: 47   QMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWT 106
            Q + ++E+   R  +         PP F    +    A G +   + ++ G P   VSW 
Sbjct: 6982 QYSCEIENEAGRD-VCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWY 7040

Query: 107  RKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
            +    L    +Y   +       +L+  ++   D GEYTC A N  G A
Sbjct: 7041 KGDTKLRPTPEYRTYFTNNVA--TLVFNKVNINDSGEYTCKAENSIGTA 7087



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 3/100 (3%)

Query: 766  TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
            T + P F+  L+ L E   G +   + Q+     P + V WYK    +  +    + F  
Sbjct: 7002 TLEPPYFVTELEPL-EAAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTN 7058

Query: 826  GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
               +L    +   D+G YT +A N +G A S    R+  R
Sbjct: 7059 NVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 7098



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F  QL    + + G      CR+       ++V WY +G +L+     +TS     A 
Sbjct: 7102 PSFARQLKD-IEQTVGLPVTLTCRLNG--SAPIQVCWYRDGVLLRDDENLQTSFVDNVAT 7158

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            L IL      SG+Y+C A N LG A SS RL  +
Sbjct: 7159 LKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 7192



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 8/102 (7%)

Query: 1968 VQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK 2027
            V + + ++EKP+   P+    VT G+P  LE  +T    P +  +W+ +GR +    +  
Sbjct: 7568 VLEPARIIEKPE---PMT---VTTGNPFALECVVT--GTPELSAKWFKDGRELSADSKHH 7619

Query: 2028 TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             T+     +L I  A   D G Y  +  N+VG++  T SV V
Sbjct: 7620 ITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHV 7661



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 47/228 (20%), Positives = 84/228 (36%), Gaps = 13/228 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F     D V++  G    + + +   G     ++WF   + +             + 
Sbjct: 7760 PPSFEQT-PDSVEVLPGMSLTFTSVI--RGTPPFKVKWFKGSRELVPGESCNISLEDFVT 7816

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LE+   +  +SG YSC  TN  G A  +  L   + +      F   + +   ++ G  
Sbjct: 7817 ELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPAT-----FVKRLADFS-VETGSP 7870

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               E T      P + + W  +   +  S R          +L+I  +   D  +Y C  
Sbjct: 7871 IVLEATYTGT--PPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLI 7928

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
             N+ G+D   A ++   +   ++E L+    A I E  +LQ     TP
Sbjct: 7929 ENEAGQDICEALVSVL-EPPYFIEPLEHVE-AVIGEPATLQCKVDGTP 7974



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 3/97 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F  PL ++E +  GE A  + ++  T  P +++ WY     L++   ++         
Sbjct: 7947 PYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNNVAS 8003

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
            L I+     D GEY C+A N+ G   ++A + ++ ++
Sbjct: 8004 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERK 8040



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 12/137 (8%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            GD    EC V     P L+  WF +G+++ + ++Y+ +       L I+     DSG Y 
Sbjct: 8527 GDTCTLECTVA--GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYS 8584

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKI--SP 2241
             +  N +G+   T +L+V+        T  P+   K++  E  G S    V E K+  SP
Sbjct: 8585 FEVQNPVGKDSCTASLQVSDR------TVPPSFTRKLK--ETNGLSGSSVVMECKVYGSP 8636

Query: 2242 PRFVTELRGTTHVFEGK 2258
            P  V+       +  G+
Sbjct: 8637 PISVSWFHEGNEISSGR 8653



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 3/110 (2%)

Query: 3263 LESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNG 3322
            +E+  G    +      EPP F+ Q++ V K+  G SA  + +L     P++ V W+   
Sbjct: 8869 IENASGKDSCSAQILILEPPYFVKQLEPV-KVSVGDSASLQCQLAGT--PEIGVSWYKGD 8925

Query: 3323 KKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             KL     Y+      +  L        +SGEY C A N +G  S    L
Sbjct: 8926 TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFL 8975



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 34/117 (29%), Positives = 49/117 (41%), Gaps = 6/117 (5%)

Query: 246   GESDVQISTEIDRSLGPVSPPKI---AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
             GESD     E       + PP++   A   R   ++ G   +    + G P P+VTW K 
Sbjct: 18123 GESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKE 18182

Query: 303   GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC-IVTSGYLAVESP 358
              +      K  I  T   + L +RN    D G Y+L  ENP G   V+   L ++ P
Sbjct: 18183 DRDA--PTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKP 18237



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 18/59 (30%), Positives = 33/59 (55%)

Query: 287   VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             + + G P P+ +W K G+ +  S+  +I +T   + L ++   + D+G YT+ A NP G
Sbjct: 21328 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 21386



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 5/104 (4%)

Query: 4511  IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             ++ P       + +V  GQ ++++  ++G     + W K+G  ++   R  + +     T
Sbjct: 24154 VIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 24213

Query: 4571  LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             L I E +  D G+Y     N  G+     E V     T DKP P
Sbjct: 24214 LSIKETHKDDGGQYGITVANVVGQKTASIEIV-----TLDKPDP 24252



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G  A+  +   G P P +TW +       ++K +I    N+T L + N  ++D+G Y
Sbjct: 24963 VRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAGKY 25020

Query: 337   TLLAENPNG 345
              L  EN +G
Sbjct: 25021 ILKLENSSG 25029



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/125 (20%), Positives = 51/125 (40%), Gaps = 1/125 (0%)

Query: 4690  EGDYKCVAYNSAGRVTVAAK-LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             E  ++  AYN  G+       + V   D         P     +  G+  + +  +  + 
Sbjct: 25207 EYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRP 25266

Query: 4749  KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +P I W+++G  + +T    +     + VL I    ++D G +T  AT +AG    +  +
Sbjct: 25267 RPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 25326

Query: 4809  VVKSK 4813
             +V  K
Sbjct: 25327 IVLEK 25331



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 4622  PPEIIE---PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             PPEI     P     V  G  ++    I GKPLP V   +    +K +  F    TA+  
Sbjct: 27400 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 27459

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAG 4702
             T+ + E+   D G Y+  A NS+G
Sbjct: 27460 TINLKESVTADAGRYEITAANSSG 27483



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 6/135 (4%)

Query: 4578  PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
             P D  ++  +A N+ G     ++    +  T+D+  P        PE  + L   I+  G
Sbjct: 28847 PGDRYEFRIIARNAVGTISPPSQSS-GIIMTRDENVPPI--VEFGPEYFDGL---IIKSG 28900

Query: 4638  QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
             +++     + G+P+P V W+K    I+     +++      +L + +A  +  G Y   A
Sbjct: 28901 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 28960

Query: 4698  YNSAGRVTVAAKLKV 4712
              N++G      K+KV
Sbjct: 28961 KNASGSAKAEIKVKV 28975



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 16/115 (13%)

Query: 4080 HMKSIEK--IREMEASW-QVTPEQVVEESKARCPPVFVSLPDAVT-----------VEEG 4125
            H+ S E+  I+E+E    + T E+++EE       V +S  +AV            + EG
Sbjct: 1246 HISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEG 1305

Query: 4126 EWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYDTG 4178
                F C+++G+P P++ W  +G  I +G RY++ +  DG     IP     D G
Sbjct: 1306 MGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1360



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 639  FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF-RFGYISLD 697
            F + +K+   +EG  + F  ++   G P  KI W K+G+ I+   R+   F + G  SL 
Sbjct: 1293 FDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLR 1350

Query: 698  MLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            +  +  +D G YT  A +  G A     L+V P A +   +  P TL+ + ++   S
Sbjct: 1351 IPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP-TLEPVSRIRSLS 1406



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLR--GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            P F++   + R  + G A FE +L   G+PT VV W     PL   N+  +R   + G  
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR--LRMINEFGYC 1760

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL        D G  TC A N+YG
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYG 1784



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P  K  I + + +  G  A F   ++   +  +R +W K GR +  S + +   +    +
Sbjct: 4383 PVIKRKI-EPLEVALGHLAKFTCEIQSAPN--VRFQWFKAGREIYESDKCSIRSSKYISS 4439

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I    V D G YTC+A N  G  + +A LT+
Sbjct: 4440 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4472



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            DR+   P FT+ L     +  G     + ++   G   +R  W+ +G E+    R+R   
Sbjct: 5035 DRDIA-PFFTKPLRNVDSVVNGT-CRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAF 5090

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
              G  +L+I  V  NDAG + C+A N  G
Sbjct: 5091 VEGTASLEIIRVDMNDAGNFTCRATNSVG 5119



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 9/124 (7%)

Query: 1973 FVVEKPQFGKPIKNAEVTE-GHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031
            FV E   F + ++ +++ + G    L   +T    P +++ W+ N R +++  + + ++ 
Sbjct: 5221 FVKEPATFVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFV 5278

Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQEL 2091
                 L +     ED+G YMC+A N  G    +S V V  K   Y      +  K I+ L
Sbjct: 5279 ESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV--KESPYF----TKEFKPIEVL 5332

Query: 2092 EKYE 2095
            ++Y+
Sbjct: 5333 KEYD 5336



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E   F + L     L +G       +V   G P ++  W+ N  E+K  S+ R +     
Sbjct: 5224 EPATFVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFVEST 5281

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
              L +  V   D+G YMC+A N AG
Sbjct: 5282 AVLRLTDVGIEDSGEYMCEAQNEAG 5306



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 2/104 (1%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F  ++K     +   +  EC V       + I+W+++ + + +  +Y+  +      
Sbjct: 5601 PPSFTKKLKKMDSIKGSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            L+I  +   DSG Y C A N  G +     ++ K+ P  + + Q
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 5702



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F + L+ +  +   + +  + +        + ++W+KD + I+AS +    F+     
Sbjct: 5602 PSFTKKLKKMDSI---KGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 830  LNIMHLRAEDAGSYTVRAVNKLG 852
            L I  L   D+G+YT  A NK G
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAG 5681



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F K +K  +  +G  + LE  +       + ++W+ + + +    ++K ++      L
Sbjct: 5602 PSFTKKLKKMDSIKGSFIDLECIVA--GSHPISIQWFKDDQEISASEKYKFSFHDNTAFL 5659

Query: 2038 DILYAYAEDTGTYMCKATNAVG 2059
            +I      D+GTY C ATN  G
Sbjct: 5660 EISQLEGTDSGTYTCSATNKAG 5681



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F +  ++ +V     V L+A +       M ++W+ + + +  G       D  
Sbjct: 5691 VKEPPYFVEKPQSQDVNPNTRVQLKALVG--GTAPMTIKWFKDNKELHSGAARSVWKDDT 5748

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              +L++  A A D+GTY+C+ +N VG A + +++ V
Sbjct: 5749 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFV 5784



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 2/103 (1%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   P    ++ N+    + + +    + M ++WF + K L +G+      D     
Sbjct: 5694 PPYFVEKPQSQDVNPNTRV--QLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTS 5751

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            LE+      D+G Y C+ +N  G AT    L VK     I +P
Sbjct: 5752 LELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKP 5794



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 5/115 (4%)

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWF 1347
            QL  D    T +    + V + PQF +    +  +  G +   EC++   G   +RV W+
Sbjct: 5768 QLSNDVGTATSKAT--LFVKEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWY 5823

Query: 1348 CNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +G  I    +   ++        +     E+SG Y C+A N  G A  S  L+V
Sbjct: 5824 LDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKV 5878



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 39/223 (17%), Positives = 84/223 (37%), Gaps = 17/223 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    ++   + +   A +++++   G   + I W  + + ++    +   +   + 
Sbjct: 5974 PPSFIKKIENTTTVLKSS-ATFQSTV--AGSPPISITWLKDDQILDEDDNVYISFVDSVA 6030

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L+I       SG Y+C+A N+ G         C      Q+P           + +   
Sbjct: 6031 TLQIRSVDNGHSGRYTCQAKNESGVE------RCYAFLLVQEPAQIVEKAKSVDVTEKDP 6084

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               EC V     P++K++W  +G+ +  S       +       I      DSG+Y  + 
Sbjct: 6085 MTLECVV--AGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKV 6142

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269
             N +G        +C     V  +++ P    K+ +++ + G+
Sbjct: 6143 ENDFGSS------SCDAYLRVLDQNIPPSFTKKLTKMDKVLGS 6179



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   VE   ++DV E  P+  +C V   G P +++ W  +G+            +    +
Sbjct: 6067 PAQIVEKAKSVDVTEKDPMTLECVV--AGTPELKVKWLKDGKQIVPSRYFSMSFENNVAS 6124

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTA 3783
              I  +  +D+G+YT +  N +GS++  A
Sbjct: 6125 FRIQSVMKQDSGQYTFKVENDFGSSSCDA 6153



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 10/124 (8%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP+F     +  I+    S+  EC++       +RV WF N   L    + +        
Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 6406

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
            ++++  +   D+G + C+A N  G  + S K+ VK       EP + S F    E+++  
Sbjct: 6407 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK-------EPPVFSSFPPIVETLKNA 6459

Query: 3676 EETL 3679
            E +L
Sbjct: 6460 EVSL 6463



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 3/99 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E    P F   +KD I    G       RL   G + ++V W +DG  +     + T 
Sbjct: 7095 IQERQLPPSFARQLKD-IEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDDENLQTS 7151

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000
            F      L I    +  +G Y+C A N +G A++SA LT
Sbjct: 7152 FVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLT 7190



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 79/383 (20%), Positives = 131/383 (34%), Gaps = 25/383 (6%)

Query: 3546 DTLTPEAESGNPPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            D  + +     PP+F     +  +  +  S   EC++       ++V WF N   L    
Sbjct: 7279 DMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESW 7336

Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
            +          +L I      D+G Y C+A N  G+A+ S  L VK       +P     
Sbjct: 7337 KYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGA 7396

Query: 3665 FKSGTESIQKLEETLHKREEITIEDEKP--NPPRFTVEIKD--------NIDVPEGGPVH 3714
             K     +Q         E + ++D K   N  +F +  K         N++  + G  H
Sbjct: 7397 LKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYH 7456

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT- 3773
                 E VG  T          P      V  L+D   +  D   + A   G        
Sbjct: 7457 CKATNE-VGSDTCSCSVKFKEPP----RFVKKLSDTSTLIGDAVELRAIVEGFQPISVVW 7511

Query: 3774 -NKWGSATTTAKITCSAKRDIVLESQL--PQGM-SGEKIKELERGRISDAPKEEPIVSTP 3829
                G     ++ T  +  D +   QL  P+   SG+ I +++             V  P
Sbjct: 7512 LKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEP 7571

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
             + I + +  TV        EC V     P+L  +W+++G+ L +  ++   +     SL
Sbjct: 7572 ARIIEKPEPMTVTTGNPFALECVV--TGTPELSAKWFKDGRELSADSKHHITFINKVASL 7629

Query: 3890 DILYVYAEDSGEYICRAVNDFGE 3912
             I      D G Y     N  G+
Sbjct: 7630 KIPCAEMSDKGLYSFEVKNSVGK 7652



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKN-GQSIEASSRFTSIFRFGYI 694
            PP+F+  L   + + G  +     +E  G   + + WLK+ G+ I  S      F     
Sbjct: 7477 PPRFVKKLSDTSTLIGDAVELRAIVE--GFQPISVVWLKDRGEVIRESENTRISFIDNIA 7534

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            +L + S    +SG+Y C+  +  G+ E  AVL V   A I
Sbjct: 7535 TLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARI 7574



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F   +KD  +I  G     E R+   G + + V W +DG  + +  +  + F+     
Sbjct: 7668 PSFIRKLKDVNAIL-GASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L +  +   D G YTC A N  G    SA LT+
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 7757



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P  I +     K++ G +   EC +   P+  +  +W+ +GK L S ++Y+ S     + 
Sbjct: 8512 PATIVEKPESIKVTTGDTCTLECTVAGTPE--LSTKWFKDGKELTSDNKYKISFFNKVSG 8569

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            L I+ V   DSG Y+ +  N +G+   +  L V  +
Sbjct: 8570 LKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 8605



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 6/95 (6%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P  + E   +  V  G T   EC V     P L  +++ +GK L S  ++ I+F F  VS
Sbjct: 8512 PATIVEKPESIKVTTGDTCTLECTVAGT--PELSTKWFKDGKELTSDNKYKISF-FNKVS 8568

Query: 2302 -LDIQHCVPEDAGEYSVKAINALG--HCTSAISMT 2333
             L I +  P D+G YS +  N +G   CT+++ ++
Sbjct: 8569 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVS 8603



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L+  + +  G +   +C++   G P + V WF     I    +   T      +
Sbjct: 8609 PSFTRKLKETNGLS-GSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 8665

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            +T++ + + D G Y C A+N+ G
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAG 8688



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            ST + V+E K+ PP F  +LR       G    F+C +    +P + + +Y +GK L+ +
Sbjct: 8972 STFLTVQEQKL-PPSFSRQLRDVQETV-GLPVVFDCAISG-SEP-ISVSWYKDGKPLKDS 9027

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
                 +F     +L+I       AG+YS  A N +G  +S+  + +T
Sbjct: 9028 PNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILT 9074



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3829 PPKFITQIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            PP F  Q++   V+E+ G  V F+C +   E   + + WY++GK L      +T +    
Sbjct: 8983 PPSFSRQLRD--VQETVGLPVVFDCAISGSEP--ISVSWYKDGKPLKDSPNVQTSFLDNT 9038

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             +L+I       +G+Y C A N  G   + A +
Sbjct: 9039 ATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G++  FEC+V  ++   +K+ W  +++ + SG +Y+ ++  +   L +    + DSG YT
Sbjct: 9094 GESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYT 9151

Query: 2848 CKATNSKGSATTSGSL 2863
            C A N  G  + +  L
Sbjct: 9152 CYAVNEVGKDSCTAQL 9167



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 3/95 (3%)

Query: 3557 PPEFTTTPSDLIL-SENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP FT   S+ +  +E +S   E R+       + V W+ N   +   S  +       +
Sbjct: 9175 PPSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTL 9232

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            +L++      DAGLYTCK +N  G A  +  + +K
Sbjct: 9233 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 9267



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 14/148 (9%)

Query: 3082  IEWFYNGKTIEASHRIRTVYAFGMV-VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
             ++WF +G+ I  S +  ++ A G+  +L+I      D G Y C       +A ++V+   
Sbjct: 12619 VKWFKDGEEIVPSPKY-SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARL 12677

Query: 3141  VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
             +   K +KP +   +        G++AHFE   + + +PD+  +W   GQP+  S   + 
Sbjct: 12678 I---KVEKPLYGVEVFV------GETAHFE---IELSEPDVHGQWKLKGQPLTASPDCEI 12725

Query: 3201  VSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
             + D    +L +   Q   +GE   +A N
Sbjct: 12726 IEDGKKHILILHNCQLGMTGEVSFQAAN 12753



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 49/208 (23%), Positives = 91/208 (43%), Gaps = 24/208 (11%)

Query: 3058  VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
             V ++ G+ A ++  L     + + +EW+  GK +E S ++       +  L +   K  D
Sbjct: 13132 VTVTAGETATFDCEL---SYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLED 13188

Query: 3118  SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             +G     A +    A + VK   V+        FT  +++ + +++G +A  EC V    
Sbjct: 13189 AGEVQLTAKDFKTHANLFVKEPPVE--------FTKPLED-QTVEEGATAVLECEV---S 13236

Query: 3178  DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF-TR 3236
               + K++W+ NG  +  S + + V+D     L I      D   Y C A     +DF T 
Sbjct: 13237 RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA-----KDFKTS 13291

Query: 3237  ATINCYGKGGVYLESLQPDSLAKIRELE 3264
               +N       ++E L+P +  ++RE E
Sbjct: 13292 CNLNVVPP---HVEFLRPLTDLQVREKE 13316



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 9/122 (7%)

Query: 3933  VPRGMKRSEALTQMEATIKKYTSEVYLTEDDLY---DVDKKQPP-RFVTQIQSQTSLVEM 3988
             VPR   +   LT  +  ++    EV LT  D     ++  K+PP  F   ++ QT + E 
Sbjct: 13169 VPRSEGKVHTLTLRDVKLED-AGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQT-VEEG 13226

Query: 3989  ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
              T   EC+   V   N KV+WF NG  +L   ++  + D     +      PED   Y C
Sbjct: 13227 ATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 13283

Query: 4049  RA 4050
              A
Sbjct: 13284 DA 13285



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/60 (36%), Positives = 31/60 (51%)

Query: 943   VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             V W KDG+ V+AS R+T   +     L +      DAG YT    N +G AT S N+ ++
Sbjct: 15345 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 15404



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 36/171 (21%), Positives = 67/171 (39%), Gaps = 12/171 (7%)

Query: 194   QGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIS 253
             QGY  E+ R  +            T  F V+  +   + E  FR       +GES+  + 
Sbjct: 16254 QGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYE--FRVKAVNE-IGESEPSLP 16310

Query: 254   TEI---DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL---- 306
               +   D  + P    +++ +    K++ G        ++G P P++ W KN   +    
Sbjct: 16311 LNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPT 16370

Query: 307   --INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
               +   K E+  +   T L +    + D G YT+ A N  G +  + ++ V
Sbjct: 16371 DALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 16421



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 6/83 (7%)

Query: 1058  GQSAHFEARVE--PQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGV 1115
             GQ+    ARV+  P+ D+T T E    GK +    R+    D   V L I      D G 
Sbjct: 18850 GQTIRILARVKGRPEPDITWTKE----GKVLVREKRVDLIQDLPRVELQIKEAVRADHGK 18905

Query: 1116  YTVVARNAAGEAQLSASMTVETR 1138
             Y + A+N++G AQ SA + V  R
Sbjct: 18906 YIISAKNSSGHAQGSAIVNVLDR 18928



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL--KSTFDFGLVTLSINSLRNDDSGI 2714
             G+   ++A +  +  P   I+W K    L+  ARL  KST DF   +LS+      DSG 
Sbjct: 23485 GESFKVDADIYGKPIPT--IQWIKGDQELSNTARLEIKST-DFA-TSLSVKDAVRVDSGN 23540

Query: 2715  YTCKATNLLGEAVSTASIKIEDR 2737
             Y  KA N+ GE   T ++K+ DR
Sbjct: 23541 YILKAKNVAGERSVTVNVKVLDR 23563



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033
            + P F +P+++  V EG     EA ++    P   V W+ +G+ +        + ++  G
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
               L I      ++G Y  KATN  G+A +T+ + V A++
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFD 1366
            QAP F++ L ++  +EG+    E  +   G     V WF +G+ I T      + ++   
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
               L + +V   +SG Y+ +ATN  G+A ++  L V A+
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/97 (32%), Positives = 48/97 (49%), Gaps = 7/97 (7%)

Query: 2944 KIEWYFNGKVLEQGSRFKLTSDF---GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            KI WY +GK ++ G R+++  DF   G  +L +  V   D GIYT  A N +G A  S  
Sbjct: 1321 KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGK 1378

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLED-SLRKEP 3036
            +Y      L   T  P   E + +I++L   S+ + P
Sbjct: 1379 LYVEPAAPLGAPTYIPT-LEPVSRIRSLSPRSVSRSP 1414



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 37/118 (31%), Positives = 50/118 (42%), Gaps = 5/118 (4%)

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            +P  IE     + P     + S + + +G  AHF  RV    DP    +W+ NG KI   
Sbjct: 2065 KPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERS 2121

Query: 2156 HR-YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQ 2212
             R Y    +     L I    AEDS + M KA N  GE  +   L V   + +I  TQ
Sbjct: 2122 DRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA-KQLITFTQ 2178



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 42/175 (24%), Positives = 69/175 (39%), Gaps = 13/175 (7%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            + +K  +D    E     F+  V+    P V WF  + +I+    H+ LV+E   H LM+
Sbjct: 2796 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLML 2853

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             N++ SD+G  T V     G+   +C+  +     V      +    + V E +      
Sbjct: 2854 QNISPSDAGEYTAVV----GQ--LECKAKLF----VETLHITKTMKNIEVPETKTASFEC 2903

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
                   P + W K+GV I  + + +I   G    L I      D+A Y     N
Sbjct: 2904 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2957



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 6/97 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P   TP+ D +S +EG   H    +     +   V W  + + V +  +     +     
Sbjct: 4289 PMIHTPLVDTVS-EEGDIVHLTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYT 4343

Query: 969  LTIKSVTVHD-AGHYTCRAYNAIGQATTSANLTIVTK 1004
            L I  V   D  G Y C A N  G+  TSA LT+V +
Sbjct: 4344 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 4380



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            G  A F C+++    PN+R +++  G+ +  + +  I       SL+I      D GEY+
Sbjct: 4397 GHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 4454

Query: 2317 VKAINALGHCTSAISMTVT 2335
             KA N  G  +   ++TVT
Sbjct: 4455 CKASNEYGSVSCTATLTVT 4473



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP FI  L+    + G     +  +   G    +I W K+ + I +S ++    +   + 
Sbjct: 4757 PPSFIKTLEPADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLFSQKSLVC 4814

Query: 696  LDMLSLNIQDSGEYTCRAVSATG 718
            L++ S N  D GEY C   +  G
Sbjct: 4815 LEIFSFNSADVGEYECVVANEVG 4837



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 3/106 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   + D I++  G     +A +   G   + V W+K    +    +I   F+ G 
Sbjct: 4849 EPPTFVKKVDDLIALG-GQTVTLQAAVR--GSEPISVTWMKGQEVIREDGKIKMSFSNGV 4905

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
              L I  V +   G YTC A N  G  T+   L +     II  ++
Sbjct: 4906 AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAE 4951



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/59 (38%), Positives = 28/59 (47%)

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I WF  NK L SG     T +    SL++      DSG YTCK +N  G    S +L
Sbjct: 5162 LTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANL 5220



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 2/93 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P  IT+      +++G  A  + +     +  +  +W+ +G+ L  G +Y+ S     + 
Sbjct: 5505 PATITEEAVSIDVTQGDPATLQVKFSGTKE--ITAKWFKDGQELTLGSKYKISVTDTVSI 5562

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            L I++   +DSGEYT +  N++G++    R+NV
Sbjct: 5563 LKIISTEKKDSGEYTFEVQNDVGRSSCKARINV 5595



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 6/139 (4%)

Query: 1666 IAIVHSKKSIYLESQHEGALPRLN-QLEDTSKYQRHSAQDEVITQAPV-FTMPMKDIRVA 1723
            I+ V S  ++ + S   G   R   Q ++ S  +R  A   ++ Q P       K + V 
Sbjct: 6023 ISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAF--LLVQEPAQIVEKAKSVDVT 6080

Query: 1724 ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTY 1783
            E      E   +  G P+L+V+WL++G  I  S   +   +    +  ++ V  +DSG Y
Sbjct: 6081 EKDPMTLEC--VVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQY 6138

Query: 1784 TCRAINELGEAVTSSTLFV 1802
            T +  N+ G +   + L V
Sbjct: 6139 TFKVENDFGSSSCDAYLRV 6157



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 3/110 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP F  +L     V  G + H EC+V       +  +++ +GK + ++A++ +      V
Sbjct: 6163 PPSFTKKLTKMDKVL-GSSIHMECKVSG--SLPISAQWFKDGKEISTSAKYRLVCHERSV 6219

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350
            SL++ +   ED   Y+ K  N  G    +  +TV    S + +  R + +
Sbjct: 6220 SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAI 6269



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 6/111 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP F   L+ T  V  G +   EC+V       + + ++H    + S A++  TF     
Sbjct: 6726 PPSFTRRLKNTGGVL-GASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVC 6782

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
            +L +      D G Y+  A N  G       +TV    S + E   PE LE
Sbjct: 6783 TLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKE---PEPLE 6830



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            SD  +    V  PP F+ + +   V   + V F   +  +  P  ++ W+R  + L  G 
Sbjct: 6807 SDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVI--RGTPPFKVNWFRGARELVKGD 6864

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            R    ++     L++  +    SGEY C   N+ G+
Sbjct: 6865 RCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQ 6900



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            VQ+ P F    +  + L  G++V   + +  R  P  K+ WF+    L  G R    F+ 
Sbjct: 6816 VQEPPSFVKEPEPLEVL-PGKNVTFTSVI--RGTPPFKVNWFRGARELVKGDRCNIYFED 6872

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             +  L + ++    SG YTC  +N  G+A  T  + +++
Sbjct: 6873 TVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE 6911



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            I +  G  A FE  +   G   +R+ W KD + +      T         L I  V   D
Sbjct: 7207 IDVIAGESADFECHVT--GAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGD 7264

Query: 979  AGHYTCRAYNAIGQATTSANLTI 1001
            +G YTC+A N +G+   SA L++
Sbjct: 7265 SGQYTCQATNDVGKDMCSAQLSV 7287



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V+  P+FT        L +G  V L+ ++     P  ++ W K+   +    + K T   
Sbjct: 7381 VKAPPVFTQKPSPVGAL-KGSDVILQCEISGT--PPFEVVWVKDRKQVRNSKKFKITSKH 7437

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               +L I +L   D G Y CKATN +G    + S+K ++
Sbjct: 7438 FDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE 7476



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 2/94 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F     D+     +S   ECR+     + + V WF +G  +++G + ++        
Sbjct: 7667 PPSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            L +  +   D G+YTC A N  G    S  L V+
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 7758



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR-TFHDFG 3338
            EPP F  Q  D  +++ G S  F +  V    P  KV+WF   ++L  G     +  DF 
Sbjct: 7759 EPPSF-EQTPDSVEVLPGMSLTFTS--VIRGTPPFKVKWFKGSRELVPGESCNISLEDF- 7814

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            +  L++       SG+Y C+ TN  G  S   +L
Sbjct: 7815 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHL 7848



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 12/125 (9%)

Query: 750  LEDYSKYQ-------HQESIEEQTS--QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDP 800
            +EDY++Y         Q+  E   S  + P FI PL+ + E   G  A  + ++     P
Sbjct: 7918 IEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHV-EAVIGEPATLQCKVD--GTP 7974

Query: 801  TMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
             +R+ WYK+   + ++      F     SL I  +   D G Y+ +A N +G   S+A +
Sbjct: 7975 EIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVL 8034

Query: 861  RVAAR 865
             +  R
Sbjct: 8035 VIKER 8039



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2129 FECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATN 2188
            FECR+   ++P L + W+ +G  ++     +T+       L IL T     G Y C A+N
Sbjct: 8062 FECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASN 8119

Query: 2189 KLGEAVNTCTLKVAGH 2204
             LG A ++  L ++ H
Sbjct: 8120 PLGTASSSAKLILSEH 8135



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  P   + + +S  V   +    EC V     P+L  +W+++GK L S ++Y+  +   
Sbjct: 8509 VLEPATIVEKPESIKVTTGDTCTLECTVAGT--PELSTKWFKDGKELTSDNKYKISFFNK 8566

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               L I+ V   DSG Y     N  G+D   A++
Sbjct: 8567 VSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASL 8600



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F  QL    + + G    ++C I    +P + V WY +GK L+     +TS     A 
Sbjct: 8984 PSFSRQLRDVQE-TVGLPVVFDCAISG-SEP-ISVSWYKDGKPLKDSPNVQTSFLDNTAT 9040

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934
            L+I       +G+Y+C A N +G A SS RL
Sbjct: 9041 LNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F + +  +     ++A FE  +   G   ++V W ++   I +  +    +      L
Sbjct: 9080 PFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHL 9137

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             +  V+  DSG YTC A+NE+G+   ++ L ++ +
Sbjct: 9138 TVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 9172



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 5/121 (4%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            + ++ ++E ++ PP F   L  T    EG +   E +V       + + +Y N   +Q  
Sbjct: 9164 TAQLNIKE-RLIPPSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPT 9220

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAISMTVTAKGSIISESQR 2346
            +   ITF    + L ++     DAG Y+ K  N  G   CTS+I +    K  +  +   
Sbjct: 9221 SNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 9280

Query: 2347 P 2347
            P
Sbjct: 9281 P 9281



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 8/101 (7%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV++ P + R L ++   EG    + C+        ++ EWF NG+ +K   R +   E
Sbjct: 9667 LTVIE-PAWERHLQDVTLKEGQTCTMTCQFSV---PNVKSEWFRNGRILKPQGRHKTEVE 9722

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                 L +  V  ED G YTC    +  +  TS  LR+ A+
Sbjct: 9723 HKVHKLTIADVRAEDQGQYTC----KYEDLETSAELRIEAE 9759



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 1314  SRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDL 1372
             S A+ ++ TV+ GTNV L+  +   G     V W  +G  +K     + A + +   L+L
Sbjct: 20225 SVAMKSLLTVKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 20282

Query: 1373  LSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
              SV  +DSG YT  A N  G    +  L+V+ K
Sbjct: 20283 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 20315



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/71 (35%), Positives = 34/71 (47%)

Query: 2004  VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
             +  PT  V W+ +  P++Q  R           L I  A  ED G Y+ K TN+ GEA+ 
Sbjct: 23099 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 23158

Query: 2064  TSSVKVDAKSG 2074
             T +V V  K G
Sbjct: 23159 TLNVIVLDKPG 23169



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/84 (27%), Positives = 35/84 (41%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F Q  ++    +G  A FE  + G P P VSW R    +       ++ +   G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155
            I  +   + G Y+  A N  G+A
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA 89



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            T  P F+  L+    + +G     + RV      T  V++Y +G +I S+   Q   +  
Sbjct: 101  TAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQISQEGD 157

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
              +L IA    EDSG Y+V A N+ G A  +A + V+    +
Sbjct: 158  LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 1/82 (1%)

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
            V EG+ A+F+ ++T   +P + W   G LI ++  F++ ++G +  L I +    DTG  
Sbjct: 1852 VLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIH-YLDIVDCKSYDTGEV 1910

Query: 4792 TCRATTAAGQVETSAKLVVKSK 4813
               A    G +E   KL ++ +
Sbjct: 1911 KVTAENPEGVIEHKVKLEIQQR 1932



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 4/99 (4%)

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            FK  +I    + + P   + +Q+   + +G  AHF  R+  VG P  + EW++N   IE 
Sbjct: 2064 FKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIER 2120

Query: 2422 SSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S RI     +     + I  V  ED    M +A N+ GE
Sbjct: 2121 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE 2159



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 3284 FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343
            F  ++QDV    +   A FE       +P +KV+W+ +G ++  G +YR   D  +  L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3344 ILYCYEENSGEYECV 3358
            IL     ++ +Y CV
Sbjct: 2233 ILTIDTSDAEDYSCV 2247



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 10/96 (10%)

Query: 771  QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-S 829
            +F + ++D+  L++ R A FE +   VS+P + V+W KD + +  + RI  I    YV  
Sbjct: 3059 EFRKHIKDIKVLEKKR-AMFECE---VSEPDITVQWMKDDQELQITDRI-KIQKEKYVHR 3113

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            L I   R  DAG YTV A    G  +STA + V  R
Sbjct: 3114 LLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3145



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERD-SGI 2983
            EG ++HL   +    +    + WYF  K++    +FK   D    TL +  V   D  G 
Sbjct: 4302 EGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4357

Query: 2984 YTCKAYNKRGEAFTSS 2999
            Y C+A N  G+  TS+
Sbjct: 4358 YVCEALNDSGKTATSA 4373



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P   + I+  EV  GH       +     P +R +W+  GR + +  +          +L
Sbjct: 4383 PVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSL 4440

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +IL     D G Y CKA+N  G    T+++ V
Sbjct: 4441 EILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4472



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LDITHTYEEDSGIYTCKAT 2851
            F C ++ +  P ++ +WF   + +    +  S     Y+S L+I  T   D G YTCKA+
Sbjct: 4402 FTCEIQSA--PNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKAS 4458

Query: 2852 NSKGSATTSGSLRCT 2866
            N  GS + + +L  T
Sbjct: 4459 NEYGSVSCTATLTVT 4473



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            N   H EC++    D  + V W  +G+ L  G   K   +     LEI     +D+G Y 
Sbjct: 4585 NKKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYV 4642

Query: 3632 CKATNRHGEATVSCKLQVK 3650
            C A+N  G ++ S  + V+
Sbjct: 4643 CTASNEAGSSSCSATVTVR 4661



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2646 THLKSYDKLVE--GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            T +K  D L+   GQ V L+A V  R    + + W K    +    ++K +F  G+  L 
Sbjct: 4852 TFVKKVDDLIALGGQTVTLQAAV--RGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLI 4909

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            I  ++    G YTC A N  G   S   + +++
Sbjct: 4910 IPDVQISFGGKYTCLAENEAGSQTSVGELIVKE 4942



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/128 (25%), Positives = 52/128 (40%), Gaps = 4/128 (3%)

Query: 3793 IVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECR 3852
            I+ + Q+  G     + E E G  S     E IV  P K I + +   V   +    E  
Sbjct: 4909 IIPDVQISFGGKYTCLAENEAG--SQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYT 4966

Query: 3853 VEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            V     P+L+ +WY++G+ L +  +YR  +      L        DSG+Y     N+ G 
Sbjct: 4967 VAGT--PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGS 5024

Query: 3913 DFTKATIS 3920
               + T +
Sbjct: 5025 SSCETTFT 5032



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F   +++V  +V G +   + ++       ++V WF +GK++    RYR     G   
Sbjct: 5040 PFFTKPLRNVDSVVNG-TCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 5096

Query: 3342 LDILYCYEENSGEYECVATNKLG-RDSTKA 3370
            L+I+     ++G + C ATN +G +DS+ A
Sbjct: 5097 LEIIRVDMNDAGNFTCRATNSVGSKDSSGA 5126



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/137 (21%), Positives = 63/137 (45%), Gaps = 11/137 (8%)

Query: 1533 RLTCRSTTDIVRSTQ---NEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEI 1589
            R++   +T ++R T     ++G    +   +    H + +V  +  ++P  T   K +E+
Sbjct: 5274 RMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIV--IVKESPYFTKEFKPIEV 5331

Query: 1590 KEGQRAHFERRLIPVSDAT--LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDS 1647
             +     ++  L+     T   ++ W+ +N  L+SG ++        V+L I+  +  D+
Sbjct: 5332 LK----EYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADA 5387

Query: 1648 GTYTCRAINALGEAVTS 1664
            G Y CR  N +G ++ S
Sbjct: 5388 GEYQCRVTNEVGSSICS 5404



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 18/61 (29%), Positives = 30/61 (49%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KD   + +  +  +      VSL I+   A DAG Y  R  N++G +I +A 
Sbjct: 5347 PPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSAR 5406

Query: 860  I 860
            +
Sbjct: 5407 V 5407



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR-TFHDFGI 3339
            PP F  +++ +   ++G     E  +V    P + ++WF + +++    +Y+ +FHD   
Sbjct: 5601 PPSFTKKLKKMDS-IKGSFIDLEC-IVAGSHP-ISIQWFKDDQEISASEKYKFSFHD-NT 5656

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L+I      +SG Y C ATNK G +    +L
Sbjct: 5657 AFLEISQLEGTDSGTYTCSATNKAGHNQCSGHL 5689



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F    +S D +     V L+A V   T P + I+WFK+   L +GA      D 
Sbjct: 5691 VKEPPYFVEKPQSQD-VNPNTRVQLKALVGG-TAP-MTIKWFKDNKELHSGAARSVWKDD 5747

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               +L + + +  DSG Y C+ +N +G A S A++ +++
Sbjct: 5748 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE 5786



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 19/82 (23%), Positives = 41/82 (50%), Gaps = 2/82 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +V + G +  FEC +  +  P +++ W+ +   + +  ++  +      +  I+    E+
Sbjct: 5798 LVLRNGQSTTFECQITGT--PKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVEN 5855

Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864
            SG Y C+A N  G+A+ S  L+
Sbjct: 5856 SGTYVCEARNDAGTASCSIELK 5877



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 2/89 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + P     LK VE+ +      E  +        +V W  NN+ ++S  ++T T+     
Sbjct: 5880 EPPTFIRELKPVEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTDRVSVF 5937

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
             L I  C P D+G Y C   N  G    S
Sbjct: 5938 NLHITKCDPSDTGEYQCIVSNEGGSCSCS 5966



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E  Q  +  K+ +VTE  P+ LE  +     P ++V+W  +G+ +     F  +++  
Sbjct: 6064 VQEPAQIVEKAKSVDVTEKDPMTLECVVA--GTPELKVKWLKDGKQIVPSRYFSMSFENN 6121

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              +  I     +D+G Y  K  N  G +   + ++V
Sbjct: 6122 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV 6157



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            E D +  EC V  +  P LK++W  + K +     +  + + +  S  I    ++DSG Y
Sbjct: 6081 EKDPMTLECVVAGT--PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQY 6138

Query: 2847 TCKATNSKGSATTSGSLRCTGDKNI 2871
            T K  N  GS++    LR   D+NI
Sbjct: 6139 TFKVENDFGSSSCDAYLRVL-DQNI 6162



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P FT+ LT   ++  G   H E +V   G   +  +W+ +G E+   +++R       V+
Sbjct: 6164 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 6220

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
            L++N++   D   Y CK  N AG
Sbjct: 6221 LEVNNLELEDTANYTCKVSNVAG 6243



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 4/95 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   VE    + V  G     +C+V   G P + ++W+ +G+   T S+ H  + +  I+
Sbjct: 6630 PAVIVEKAGPMTVTVGETCTLECKV--AGTPELSVEWYKDGK-LLTSSQKHKFSFYNKIS 6686

Query: 3755 -LDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
             L I  +  +DAG YT +  N  G ++ TA +  S
Sbjct: 6687 SLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVS 6721



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 37/160 (23%), Positives = 71/160 (44%), Gaps = 15/160 (9%)

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTT 1575
            I T    N+V T++     TC    +I+ ST+ +AG    ++  +  +     +V   T 
Sbjct: 6953 ITTSEKCNIVTTEK-----TC--ILEILNSTKRDAGQYSCEIENEAGRDVCGALVS--TL 7003

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE--TNNFG 1633
            + P   T L+ +E   G     + ++    + T  V WY  +  L+    +    TNN  
Sbjct: 7004 EPPYFVTELEPLEAAVGDSVSLQCQVAGTPEIT--VSWYKGDTKLRPTPEYRTYFTNNVA 7061

Query: 1634 FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
             +  + ++    DSG YTC+A N++G A +  +  +  ++
Sbjct: 7062 TLVFNKVNI--NDSGEYTCKAENSIGTASSKTVFRIQERQ 7099



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  Q++D+ + V G       RL       ++V W+ +G  L      +T     + 
Sbjct: 7101 PPSFARQLKDIEQTV-GLPVTLTCRLN--GSAPIQVCWYRDGVLLRDDENLQTSFVDNVA 7157

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             L IL     +SG+Y C A+N LG  S+ A L
Sbjct: 7158 TLKILQTDLSHSGQYSCSASNPLGTASSSARL 7189



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F + L       +G+    E ++   G P ++  W+ N  EL    ++  +     
Sbjct: 7289 EPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSV 7346

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
              L IN   A D+G Y+C+A N  G
Sbjct: 7347 ALLTINEASAEDSGDYICEAHNGVG 7371



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P  +     P  V+ G    LEC +   G P +  +WF +GR ++  S+    +     
Sbjct: 7570 EPARIIEKPEPMTVTTGNPFALECVVT--GTPELSAKWFKDGRELSADSKHHITFINKVA 7627

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            +L I  A  +D G Y+    N +G ++ +  V V +R
Sbjct: 7628 SLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDR 7664



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 20/65 (30%), Positives = 30/65 (46%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G + +++ W KD R +                LT+  V   DAG YTC A N  G+ + S
Sbjct: 8164 GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCS 8223

Query: 997  ANLTI 1001
            A+L +
Sbjct: 8224 AHLGV 8228



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 20/75 (26%), Positives = 34/75 (45%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            K  P   + W+     L  G R  ++ +     L+L DV    SG YTC   N+ G+A  
Sbjct: 8726 KGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASC 8785

Query: 2998 SSTVYCTSKDNLIER 3012
            ++ +Y  +    ++R
Sbjct: 8786 TTHLYIKAPAKFVKR 8800



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            ++    +F K + +  + +G P+ LE T T    P + V W  NG  V    R   T   
Sbjct: 8790 YIKAPAKFVKRLNDYSIEKGKPLILEGTFT--GTPPISVTWKKNGINVTPSQRCNITTTE 8847

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L+I  +  ED G Y C   NA G+   ++ + +
Sbjct: 8848 KSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILI 8884



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L  +    GD+   +C +  +  P + + W+  +  L   T YK     +  +L  
Sbjct: 8890 FVKQLEPVKVSVGDSASLQCQLAGT--PEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVF 8947

Query: 2836 THTYEEDSGIYTCKATNSKGSATTS 2860
                  DSG Y CKA NS G  + S
Sbjct: 8948 NQVDINDSGEYICKAENSVGEVSAS 8972



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)

Query: 4086 KIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWL 4145
            K+     S   T   V++E K   PPVF      VTV EGE+ +  C V G    R+ WL
Sbjct: 9250 KVSNDAGSALCTSSIVIKEPKK--PPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWL 9307

Query: 4146 LNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTG 4178
              G  I    R   ++  G    ++    + D+G
Sbjct: 9308 KAGREIKPSDRCSFSFASGTAVLELRDVAKADSG 9341



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 18/47 (38%), Positives = 26/47 (55%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCK 2987
            P++K EW+ NG++L+   R K   +     L + DV   D G YTCK
Sbjct: 9698 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 9744



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 3818  DAPKEEPIVSTPPKFITQIKSHTVEESEGVR----FECRVEPKEDPKLRIEWYRNGKLLP 3873
             +AP    + + P KF+ +IK   + ESE V     FEC V P         W ++G  + 
Sbjct: 12030 EAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPST---AITTWMKDGSNIR 12086

Query: 3874  SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                ++R + D     L I+ V   D+GEY C       E  + A +  ++LP
Sbjct: 12087 ESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP 12138



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 9/100 (9%)

Query: 2222  QLEAQGHSTRIE--VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
             QL A+   T     V+EP   P  F   L   T V EG TA  EC+V      N +++++
Sbjct: 13193 QLTAKDFKTHANLFVKEP---PVEFTKPLEDQT-VEEGATAVLECEVSR---ENAKVKWF 13245

Query: 2280  HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKA 2319
              NG  +  + ++ I  D     L I  C PED   Y+  A
Sbjct: 13246 KNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 13285



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)

Query: 4613  KPQT-KAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             KP T K   APP +    +DK+ +  G+A   + +  GKP P V W+K +  +       
Sbjct: 17734 KPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTH 17793

Query: 4671  MSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
             +  T     L   +A   D G Y  V  NS G
Sbjct: 17794 IKTTPATLALEKIKAKRSDSGKYCVVVENSTG 17825



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/112 (24%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 245   VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
             +G  D  I  E    L P S     +      ++ G   +F   + G P P   W  +G 
Sbjct: 18417 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGS 18476

Query: 305   RLINSNKHEIITTHNHTT-LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
               I +++H  + T N ++ L ++N  + D+G Y +   N  G    + +L V
Sbjct: 18477 E-IKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 18527



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 21/69 (30%), Positives = 32/69 (46%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
             V  G+ ++     +G+P P V W+K +  +K +       T +   L I +A  ED G Y
Sbjct: 23086 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 23145

Query: 4694  KCVAYNSAG 4702
                  NSAG
Sbjct: 23146 VVKLTNSAG 23154



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 2/90 (2%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P  +  F +     G + K E  + G P P ++WT+   PL +  + ++   +     +L
Sbjct: 24157 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV--TDSLDLTTL 24214

Query: 132   LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              IK+    D G+Y  T  N  G+   S+ I
Sbjct: 24215 SIKETHKDDGGQYGITVANVVGQKTASIEI 24244



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/78 (28%), Positives = 37/78 (47%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  R E +  G+PLP I+W R +  I+ S   +I     K++LI++     D   +   A
Sbjct: 24568 ETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRA 24627

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N  G+     N+ V ++
Sbjct: 24628 SNVAGSKSFPVNVKVLDR 24645



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 4620  NAPPEIIEP-LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
             +AP   ++P  KD IV   G+       I GKP+P V W K G +L + +   ++  T  
Sbjct: 25630 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 25689

Query: 4677  EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             + TL + +    D G Y     N  G  ++   +KV
Sbjct: 25690 KTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 25725



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ GA     V   G P P V W K    L    +  + TT + T+L + N  ++DSG Y
Sbjct: 27125 VKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYVDTTDSRTSLTIENANRNDSGKY 27182

Query: 337   TLLAEN 342
             TL  +N
Sbjct: 27183 TLTIQN 27188



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 10/133 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP FV ++QS T     + ++   Q+   G P   V+++ +G  +     F    +    
Sbjct: 103  PPNFVQRLQSMTV---RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP-KHMKSIEKIREM 4090
            ++     YPEDSG Y   ATN  G   + A +   G      + ++P K  K+I    ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EEEVPAKKTKTIVSTAQI 213

Query: 4091 EASWQVTPEQVVE 4103
              S Q   E+ +E
Sbjct: 214  SESRQTRIEKKIE 226



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            +E P+  + I++  V +G   H    +    DP    EWY NG  +++  R    +    
Sbjct: 2075 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDN 2132

Query: 2035 VA-LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            V  L I    AED+ + M KA N  GE  + + + V AK
Sbjct: 2133 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 2/100 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F+++ KS T    +  +F C V     P +   W ++G  L     ++         
Sbjct: 4477 PPTFLSRPKSLTTFVGKAAKFICTVTGT--PVIETIWQKDGAALSPSPNWKISDAENKHI 4534

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            L++  +  +D G Y C+A N FG D  +A +     P  I
Sbjct: 4535 LELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFI 4574



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            VH +C+V+   D  + + W  +G+    G       +     L+I     +D+G Y C A
Sbjct: 4588 VHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTA 4645

Query: 3773 TNKWGSATTTAKIT 3786
            +N+ GS++ +A +T
Sbjct: 4646 SNEAGSSSCSATVT 4659



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 46/172 (26%), Positives = 74/172 (43%), Gaps = 14/172 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L   + ++ G  A  +C V         I WF + ++IR+  +YR       V 
Sbjct: 4758 PSFIKTLEPADIVR-GTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLFSQKSLVC 4814

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGH 2228
            L+I    + D G Y C   N++G+    C   +A H    L  + P  ++K+  L A G 
Sbjct: 4815 LEIFSFNSADVGEYECVVANEVGKC--GC---MATH----LLKEPPTFVKKVDDLIALGG 4865

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFE-GK-TAHFECQVEPVHDPNLRIEF 2278
             T       + S P  VT ++G   + E GK    F   V  +  P+++I F
Sbjct: 4866 QTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISF 4917



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            I Q+P       G+  ++ G +   ++    Q    +T+ W+   K++ S        + 
Sbjct: 5128 IVQEPPSFVTKPGSKDVLPGSAVCLKSTF--QGSTPLTIRWFKGNKELVSGGSCYITKEA 5185

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
               +L++  V+  DSG YT    N AG  + SA++ V+
Sbjct: 5186 LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 5223



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P FT+    P E+ +       A V   G P     W+ +   L+ G +++T      
Sbjct: 5318 ESPYFTKEFK-PIEVLKEYDVMLLAEVA--GTPPFEITWFKDNTILRSGRKYKTFIQDHL 5374

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
            V+L I   VA DAG Y C+  N  G
Sbjct: 5375 VSLQILKFVAADAGEYQCRVTNEVG 5399



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/72 (27%), Positives = 34/72 (47%)

Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            ++W+ + + + +  +Y+ S     A L+I  + G DSG YTC A N  G    S  L V+
Sbjct: 5633 IQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 5692

Query: 1938 SKESIIRDSQHE 1949
                 +   Q +
Sbjct: 5693 EPPYFVEKPQSQ 5704



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 5/137 (3%)

Query: 1801 FVQSKASLQLESQHESALQKIQ-QLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
            FV S A+LQ+ S       +   Q ++ S  +R       + Q P  I +      ++E 
Sbjct: 6025 FVDSVATLQIRSVDNGHSGRYTCQAKNESGVERC--YAFLLVQEPAQIVEKAKSVDVTEK 6082

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
                 EC +   P+  ++V+W  +GK +     +  S +   A+  I +V  +DSG+YT 
Sbjct: 6083 DPMTLECVVAGTPE--LKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTF 6140

Query: 1920 KAINNLGQAVSSIRLNV 1936
            K  N+ G +     L V
Sbjct: 6141 KVENDFGSSSCDAYLRV 6157



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/98 (20%), Positives = 48/98 (48%), Gaps = 2/98 (2%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            +T+ P+F+  L+ +  +  G S+  E ++    ++   V W+ N  ++ ++++ +     
Sbjct: 6346 VTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIR--VVWFRNEHELPASDKYRMTFID 6403

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                + + ++  EDSG +   A+N AG    S  + V+
Sbjct: 6404 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 6441



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 2/94 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F++ P  +   +N+    EC L         V W+ + + L +  + K  +      
Sbjct: 6443 PPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNFHTS 6500

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            + I  V   D G Y CKA N  G  T  C +++K
Sbjct: 6501 IHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLK 6534



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/117 (21%), Positives = 53/117 (45%), Gaps = 4/117 (3%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYRTVYDMGFV 3887
            PP+F++++ S TV   E    +  +E  +   + ++W +  + ++      R  +     
Sbjct: 6536 PPRFVSKLNSLTVVAGEPAELQASIEGAQP--IFVQWLKEKEEVIRESENIRITFVENVA 6593

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            +L        ++G+YIC+  ND G +   AT+   + P +I++   P  +   E  T
Sbjct: 6594 TLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLE-PAVIVEKAGPMTVTVGETCT 6649



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G    LE  +     P + VEWY +G+ +    + K ++     +L IL    +D G
Sbjct: 6642 VTVGETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAG 6699

Query: 2049 TYMCKATNAVGEAVTTSSVKVDAKS 2073
            TY  +  N VG++  T+ V V  ++
Sbjct: 6700 TYTFQVQNNVGKSSCTAVVDVSDRA 6724



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 2/81 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L N     G +   EC V  S    + + WF     + SG +Y++T   +  +L +
Sbjct: 6729 FTRRLKNTGGVLGASCILECKVAGSSP--ISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 6786

Query: 2836 THTYEEDSGIYTCKATNSKGS 2856
                  D G YTC A N  GS
Sbjct: 6787 NSLDSSDMGNYTCVAANVAGS 6807



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 3/90 (3%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            + PP FVTEL        G +   +CQV     P + + +Y     L+    +   F   
Sbjct: 7003 LEPPYFVTELE-PLEAAVGDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYFTNN 7059

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              +L        D+GEY+ KA N++G  +S
Sbjct: 7060 VATLVFNKVNINDSGEYTCKAENSIGTASS 7089



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 11/110 (10%)

Query: 2229 STRIEVEEPKI--SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ 2286
            ST ++V+EP I    P  +  L+G          H EC+++    P   + +Y + + L+
Sbjct: 8317 STSLKVKEPPIFRKKPHPIETLKGAD-------VHLECELQGT--PPFHVSWYKDKRELR 8367

Query: 2287 SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
            S  ++ I  +    S+ I +    D GEY  KA N +G  T   S+ + A
Sbjct: 8368 SGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA 8417



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 38/174 (21%), Positives = 73/174 (41%), Gaps = 11/174 (6%)

Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081
            Y+E+AS        ++ I + P F+  L+   K+  G SA  + ++    ++   V WY 
Sbjct: 8868 YIENASGKDS-CSAQILILEPPYFVKQLEPV-KVSVGDSASLQCQLAGTPEIG--VSWYK 8923

Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
               ++      + +       L    V   DSG Y   A N+ GE   S  +TV+ +   
Sbjct: 8924 GDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLP 8983

Query: 1142 DTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
             + S       + R ++E+  +  ++    IS S+P+ V    +  P+ +  N+
Sbjct: 8984 PSFS------RQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPLKDSPNV 9030



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F + L  P ++  G  A  + ++   G P +   WY    +L+  + ++       
Sbjct: 8886 EPPYFVKQLE-PVKVSVGDSASLQCQLA--GTPEIGVSWYKGDTKLRPTTTYKMHFRNNV 8942

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             TL  N V  ND+G Y+CKA N  G
Sbjct: 8943 ATLVFNQVDINDSGEYICKAENSVG 8967



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F + L+ +  +  G +A   C+L   G P + V W++ +  +  ++           +
Sbjct: 8888 PYFVKQLEPV-KVSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVAT 8944

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            +  + V   D G Y+C+A N +GE
Sbjct: 8945 LVFNQVDINDSGEYICKAENSVGE 8968



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 3/90 (3%)

Query: 1585 KNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLP 1644
            + VE  EG     E R+       + V WY NN  ++  S    T     + L +     
Sbjct: 9184 ETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGM 9241

Query: 1645 EDSGTYTCRAINALGEAV-TSGIAIVHSKK 1673
             D+G YTC+  N  G A+ TS I I   KK
Sbjct: 9242 NDAGLYTCKVSNDAGSALCTSSIVIKEPKK 9271



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984
            EG    LEG+V       + + WY N   ++  S  ++T     + L +      D+G+Y
Sbjct: 9190 EGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLY 9247

Query: 2985 TCKAYNKRGEAFTSSTV 3001
            TCK  N  G A  +S++
Sbjct: 9248 TCKVSNDAGSALCTSSI 9264



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 57/279 (20%), Positives = 99/279 (35%), Gaps = 31/279 (11%)

Query: 995  TSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNK 1054
            T  N T+V +  +     +  GL   +   DA      +   +K  +KP           
Sbjct: 9226 TFKNNTLVLQ--VRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT 9283

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            + EG+       V  Q    + ++W   G++I  ++R       G   L++  V   DSG
Sbjct: 9284 VSEGEYVQLSCHV--QGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSG 9341

Query: 1115 VYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISK 1174
             Y   A N AG     + +T++ + ++  ++      +K        FV     I  + K
Sbjct: 9342 DYVCKASNVAGSDTTKSKVTIKDKPAVAPAT------KKAAVDGRLFFVSEPQSIRVVEK 9395

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFH-NGRSVTVGSRFKTYYDFG 1233
            +   F+  +                     GDP   V+W     R +  G R   +    
Sbjct: 9396 TTATFIAKVG--------------------GDPIPNVKWTKGKWRQLNQGGRVFIHQKGD 9435

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
               L+I   T  D+G Y   A N  G   ++  ++V ER
Sbjct: 9436 EAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 9474



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             V EG+ + +      +  PT  V W  +G+ V    R     D     L++  +  AD G
Sbjct: 15325 VIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAG 15382

Query: 1249  EYTVRAVNHLGSAHTSAIVRVI 1270
              YT+   N LGSA  S  V+VI
Sbjct: 15383 IYTITLENKLGSATASINVKVI 15404



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 2/61 (3%)

Query: 1076  TVEWYFNGKQITSANRIQTYHDFGYVALDI-ASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
             TV W+ +GK++ +++R+   +D     L++  SVRA D+G+YT+   N  G A  S ++ 
Sbjct: 15344 TVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DAGIYTITLENKLGSATASINVK 15402

Query: 1135  V 1135
             V
Sbjct: 15403 V 15403



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/64 (34%), Positives = 31/64 (48%)

Query: 3591  VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             V W  +GK +    R+   ND     LE+    + DAG+YT    N+ G AT S  ++V 
Sbjct: 15345 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 15404

Query: 3651  GRQG 3654
             G  G
Sbjct: 15405 GLPG 15408



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/74 (29%), Positives = 40/74 (54%)

Query: 4523  VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
             V + +G+  RL+  V+G  P  + W K+GK+++   + +I   D +  L+  ++  +DSG
Sbjct: 22398 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 22457

Query: 4583  KYECVAINSAGEAR 4596
              Y   A N  G A+
Sbjct: 22458 AYTLTATNPGGFAK 22471



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 782   LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
             +Q G +   E  +  +  P   + W KDG P+  ++R+          L+I     +D G
Sbjct: 25250 IQAGEDLKIEIPV--IGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 25307

Query: 842   SYTVRAVNKLGEAISTASIRV 862
              YTV A N  G A    S+ V
Sbjct: 25308 KYTVTATNSAGTATENLSVIV 25328



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 19/64 (29%), Positives = 30/64 (46%)

Query: 284   QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
             +  V   G P+  V W K+GQ L  + +  + ++   T+L ++   K D G Y L   N 
Sbjct: 26340 KIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 26399

Query: 344   NGCI 347
              G I
Sbjct: 26400 AGSI 26403



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/86 (25%), Positives = 47/86 (54%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQK--PRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             + PP+I  K  P ++  ++ G++ +  + +SG P P+VT  ++G  L  + +     T  
Sbjct: 27398 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 27457

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
             + T+ ++ +  +D+G Y + A N +G
Sbjct: 27458 NLTINLKESVTADAGRYEITAANSSG 27483



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +TTQAP  T  L++V + EG  A FE  +   PV +    V W+ + + + + +      
Sbjct: 1    MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQI 56

Query: 1631 NF--GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            +F  G   L I +    +SG Y+ +A N  G+A ++   +V ++
Sbjct: 57   SFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 46/180 (25%), Positives = 69/180 (38%), Gaps = 16/180 (8%)

Query: 396  KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
            K  ++ +V E K   F+C V+    P + W  N  +I      KI+V +   H L+I N 
Sbjct: 2886 KTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVV-QGKLHQLIIMNT 2943

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARA 514
            +  DS            E  F C  + +     V P  +      +N  E + +      
Sbjct: 2944 STEDSA-----------EYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEV-T 2991

Query: 515  VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            V        W K+GV I    + ++ T     +L+I      DAA Y   A   A STAT
Sbjct: 2992 VNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA-GKATSTAT 3050



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/118 (24%), Positives = 45/118 (38%), Gaps = 2/118 (1%)

Query: 3541 YSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL 3600
            Y     T T       PP F + P  L      +A F C +       +   W  +G  L
Sbjct: 4461 YGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTV--TGTPVIETIWQKDGAAL 4518

Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILE 3658
                  K  +     ILE+  +  +D G+Y+CKA+N+ G      +L +  +   I E
Sbjct: 4519 SPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKE 4576



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F+   KS+T   G    F   +   G P ++  W K+G ++  S  +          
Sbjct: 4477 PPTFLSRPKSLTTFVGKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWKISDAENKHI 4534

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVL 726
            L++ +L IQD G Y+C+A +  G    +A L
Sbjct: 4535 LELSNLTIQDRGVYSCKASNKFGADICQAEL 4565



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
            +P FI+ L+ + +    +  H E Q+    D  + V W KDG+ +         F     
Sbjct: 4570 KPHFIKELEPV-QSAINKKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYKICFEDKIA 4626

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +L I   + +D+G+Y   A N+ G +  +A++ V
Sbjct: 4627 TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 4660



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 1974 VVEKPQFGKPIKNAEVT-EGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P F K +  + +   G    L   L     P ++V W+ N + + + +  +  +  
Sbjct: 4660 VREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVN 4717

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                LDI     ED+G+Y C+A N VG    ++ + +
Sbjct: 4718 SEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI 4754



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ I + P F+  L+  + IV G +A  +  V         + W+ + KQI S+ + + +
Sbjct: 4751 EIVIKEPPSFIKTLEPAD-IVRGTNALLQCEVSGTGPFE--ISWFKDKKQIRSSKKYRLF 4807

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSAS 1132
                 V L+I S  + D G Y  V  N  G+    A+
Sbjct: 4808 SQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMAT 4844



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 9/118 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F+  +  + A+ G  +  +  +   G   + + W+K  + I    +    F  G   
Sbjct: 4850 PPTFVKKVDDLIALGGQTVTLQAAVR--GSEPISVTWMKGQEVIREDGKIKMSFSNGVAV 4907

Query: 696  LDMLSLNIQDSGEYTC----RAVSATGVAE--TKAVLHVTPRA-TIERTSQHPETLQY 746
            L +  + I   G+YTC     A S T V E   K    +  RA  I+ T+  P TL+Y
Sbjct: 4908 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEY 4965



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 19/68 (27%), Positives = 32/68 (47%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P +K +W K+G+ + AS ++   F+     L   S  + DSG+YT    +  G +  +
Sbjct: 4969 GTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCE 5028

Query: 724  AVLHVTPR 731
                V  R
Sbjct: 5029 TTFTVLDR 5036



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 3/116 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V + P F     + + + G+ V L+   Q  G   + + WF   K + +G       E
Sbjct: 5127 LIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQ--GSTPLTIRWFKGNKELVSGGSCYITKE 5184

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK 1420
                +L+L  V   DSG YTC+ +N  G    S  L  + +    +E   PS L K
Sbjct: 5185 ALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANL-FVKEPATFVEKLEPSQLLK 5239



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/126 (25%), Positives = 50/126 (39%), Gaps = 3/126 (2%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV  PP F+T+  S  V     V  +   +      L I W++  K L SG       + 
Sbjct: 5128 IVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTP--LTIRWFKGNKELVSGGSCYITKEA 5185

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
               SL++  V   DSG Y C+  N  G     A +  K+ P   ++   P  + +    T
Sbjct: 5186 LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE-PATFVEKLEPSQLLKKGDAT 5244

Query: 3945 QMEATI 3950
            Q+   +
Sbjct: 5245 QLACKV 5250



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 3/102 (2%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P FI+ ++    L+ G  A F+A L   S P + V W KD   IT    I   F     S
Sbjct: 5413 PSFIKKIESTSSLRGG-TAAFQATLKG-SLP-ITVTWLKDSDEITEDDNIRMTFENNVAS 5469

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTAD 871
            L +  +  +  G Y  +A N  G    +A + V   +T+T +
Sbjct: 5470 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEE 5511



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 23/98 (23%), Positives = 51/98 (52%), Gaps = 6/98 (6%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            QV+     ++  +W+ +G+ L  GS++K++       L ++   ++DSG YT +  N  G
Sbjct: 5526 QVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVG 5585

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDS 3031
             +       C ++ N+++    P  T+ L+K+ +++ S
Sbjct: 5586 RS------SCKARINVLDLIIPPSFTKKLKKMDSIKGS 5617



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 4/94 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT-TMHDFGYVA 1769
            P FT  +K  ++   + +  +   I  G   + ++W ++   I AS +   + HD     
Sbjct: 5602 PSFTKKLK--KMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHD-NTAF 5658

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            L +  +   DSGTYTC A N+ G    S  L V+
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 5692



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YD 4162
            E K + PP F+     V V +       C VTG P   V WL N   I +  +Y LT   
Sbjct: 5875 ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV 5934

Query: 4163 GMYHFDIPKTRQYDTGKIEVI 4183
             +++  I K    DTG+ + I
Sbjct: 5935 SVFNLHITKCDPSDTGEYQCI 5955



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F+ +++    +V+    + EC++   G P  +V W  N + +    ++T      
Sbjct: 5879 KEPPTFIRELKP-VEVVKYSDVELECEVT--GTPPFEVTWLKNNREIRSSKKYTLTDRVS 5935

Query: 4030 YVAMNFGWVYPEDSGEYLCRATN 4052
               ++     P D+GEY C  +N
Sbjct: 5936 VFNLHITKCDPSDTGEYQCIVSN 5958



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 18/83 (21%), Positives = 38/83 (45%), Gaps = 2/83 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F K +   +   G  +H+E  ++      +  +W+ +G+ +    +++       V+L
Sbjct: 6164 PSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSL 6221

Query: 2038 DILYAYAEDTGTYMCKATNAVGE 2060
            ++     EDT  Y CK +N  G+
Sbjct: 6222 EVNNLELEDTANYTCKVSNVAGD 6244



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 19/79 (24%), Positives = 42/79 (53%), Gaps = 2/79 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+    EC+V     P L+++W+ +G+ + +  +++ +      +L IL    +D+GTY 
Sbjct: 6645 GETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 6702

Query: 2184 CKATNKLGEAVNTCTLKVA 2202
             +  N +G++  T  + V+
Sbjct: 6703 FQVQNNVGKSSCTAVVDVS 6721



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 8/104 (7%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG---VPIEASNRLTTMH 1763
            + + P F      + V    +  F +  +  G P  +V+W +     VP E+ N   ++ 
Sbjct: 7757 VQEPPSFEQTPDSVEVLPGMSLTFTS--VIRGTPPFKVKWFKGSRELVPGESCN--ISLE 7812

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            DF    L +  V P +SG Y+C   N+ G A  ++ LFV+  A+
Sbjct: 7813 DF-VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPAT 7855



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 3/107 (2%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            + V + P F+ Q   P  +  G +  +   ++  P     V W+     L  G R   S 
Sbjct: 8696 LTVREPPSFV-QKPDPMDVLTGTNVTFTSIVKGTPP--FSVSWFKGSSELVPGDRCNVSL 8752

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            +   A L++  V    SGEYTC   N  G+A  +  L +++    ++
Sbjct: 8753 EDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVK 8799



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/66 (36%), Positives = 30/66 (45%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   + V W K+G  V  S R           L I S TV DAG Y C   NA G+ + S
Sbjct: 8820 GTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCS 8879

Query: 997  ANLTIV 1002
            A + I+
Sbjct: 8880 AQILIL 8885



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            + PP FV +L     V  G +A  +CQ+     P + + +Y     L+    + + F   
Sbjct: 8885 LEPPYFVKQLE-PVKVSVGDSASLQCQLAGT--PEIGVSWYKGDTKLRPTTTYKMHFRNN 8941

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              +L        D+GEY  KA N++G  +++  +TV
Sbjct: 8942 VATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV 8977



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 2/94 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   L+ V    G  + F+  I   G   + + W K+G+ ++ S    + F     +
Sbjct: 8983 PPSFSRQLRDVQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNVQTSFLDNTAT 9040

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
            L++   +   +G+Y+C A +  G A + A L +T
Sbjct: 9041 LNIFKTDRSLAGQYSCTATNPIGSASSSARLILT 9074



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F+  L+   + V G  V  +  +   ++P + + W+K+G  L     ++++F     T
Sbjct: 8984 PSFSRQLRDVQETV-GLPVVFDCAISG-SEP-ISVSWYKDGKPLKDSPNVQTSFLDNTAT 9040

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
            L+I       +G Y+C ATN +G A S+A +
Sbjct: 9041 LNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 3/86 (3%)

Query: 636  PPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            PP F   L ++V   EG     E R+   G   + + W KN   I+ +S     F+   +
Sbjct: 9175 PPSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTL 9232

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVA 720
             L +    + D+G YTC+  +  G A
Sbjct: 9233 VLQVRKAGMNDAGLYTCKVSNDAGSA 9258



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 8/97 (8%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P +   +Q  T L E +T    CQ +    PN+K EWF NG+ L  + R     +     
Sbjct: 9672 PAWERHLQDVT-LKEGQTCTMTCQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHK 9727

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            +    V  ED G+Y C+  +L    ET A ++   +P
Sbjct: 9728 LTIADVRAEDQGQYTCKYEDL----ETSAELRIEAEP 9760



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 6/108 (5%)

Query: 1033 TEEEVKITQKP-RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR 1091
            T  E++I  +P +F   ++    + E QSA FE  V     +   V WY    ++T + +
Sbjct: 9750 TSAELRIEAEPIQFTKRIQNI-VVSEHQSATFECEVSFDDAI---VTWYKGPTELTESQK 9805

Query: 1092 IQTYHDFGYVALDIASVRAEDSGVYTVVAR-NAAGEAQLSASMTVETR 1138
                +D     + I +V  +D GVY+V+AR    GEA+ +A + + T+
Sbjct: 9806 YNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTK 9853



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 7/93 (7%)

Query: 3557  PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
             P EFT    D  + E ++A  EC    V+  + +V+WF NG  +L   + + + D     
Sbjct: 13211 PVEFTKPLEDQTVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRK 13267

Query: 3617  LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             L I      D   YTC A     +   SC L V
Sbjct: 13268 LVIHDCTPEDIKTYTCDAK----DFKTSCNLNV 13296



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 4/74 (5%)

Query: 3422  FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
             F  PL++++ +RE E A FE  L+     N KV+W+ +G  +K G ++         IL 
Sbjct: 13303 FLRPLTDLQ-VREKEMARFECELSRE---NAKVKWFKDGAEIKKGKKYDIISKGAVRILV 13358

Query: 3482  ISPTYPEDSGEYLC 3495
             I+    +D  EY C
Sbjct: 13359 INKCLLDDEAEYSC 13372



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 8/91 (8%)

Query: 262   PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH--- 318
             P  PP I  K    +++EG +     ++ G P P +TWFK   +  ++ +  +  TH   
Sbjct: 17041 PDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNK 17099

Query: 319   ----NHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 +  TL +  +++SD+G YT+ A N  G
Sbjct: 17100 LVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 17130



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/137 (23%), Positives = 53/137 (38%), Gaps = 5/137 (3%)

Query: 4069  PGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVF--VSLPDAVTVEEGE 4126
             PG++  ++    +K+   + E E   +   E V+ +     P V   V+  D +TV  G+
Sbjct: 18794 PGLIEGNEYRFRIKAANIVGEGEP--RELAESVIAKDILHPPEVELDVTCRDVITVRVGQ 18851

Query: 4127  WARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXX 4185
               R   RV G P+P + W   G  +V   R  L  D       I +  + D GK  +   
Sbjct: 18852 TIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAK 18911

Query: 4186  XXXXXXXXXXXLKVIPR 4202
                        + V+ R
Sbjct: 18912 NSSGHAQGSAIVNVLDR 18928



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 22/71 (30%), Positives = 35/71 (49%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             + VR G+ + + AR  G P P ITW K+G  ++    + +  D     L I  A  +D  
Sbjct: 18845 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 18904

Query: 560   WYQCTAQNVAG 570
              Y  +A+N +G
Sbjct: 18905 KYIISAKNSSG 18915



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 4/60 (6%)

Query: 287   VQLSGNPRPRVTWFKN-GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             V + G P P V W ++ G+ L   +K  I +T ++T L V N  + DSG Y L  EN +G
Sbjct: 22809 VPIKGRPAPEVKWARDHGESL---DKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG 22865



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 8/170 (4%)

Query: 194   QGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE-SITKRYVGE-SDVQ 251
             QGY  E+        +T  T  +  +   ++  +     E +FR  +I K  VGE +DV 
Sbjct: 23797 QGYIVEKC-DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP 23855

Query: 252   ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311
                 ++  L         +  +   ++ G   +  V + G P P V W K    + ++  
Sbjct: 23856 GPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAI 23915

Query: 312   HEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG---CIVTSGYLAVESP 358
              ++  T + T+L + N  + DSG YTL  EN +G     VT   L   SP
Sbjct: 23916 IDV--TSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSP 23963



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 263   VSPPKI---AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             + PP+I   A   +   L+  A  +  V + G P P V W K     I +++ +I  T +
Sbjct: 26029 IEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK--AEGILTDRAQIEVTSS 26086

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
              T L + N  + DSG Y L  EN +G
Sbjct: 26087 FTMLVIDNVTRFDSGRYNLTLENNSG 26112



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSL 2833
            F   L ++V  EG    FE ++  S  P  ++ WF + + + + T       FS     L
Sbjct: 8    FTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I    + +SG Y+ KATN  G AT++  L
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 3/91 (3%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS-NDFGFAALDILTVYGED 1913
            K  EGQ+A ++ ++   P P     W+ +G+ + + + ++    + G  +L I+     D
Sbjct: 1467 KCLEGQTARFDLKVVGRPMPE--TFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSD 1524

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            SGE+T  A N  G++  S+ L V++ E  ++
Sbjct: 1525 SGEWTVVAQNRAGRSSISVILTVEAVEHQVK 1555



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 15/157 (9%)

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA 4723
            K   Y ++ R   +  L  ++   E+E   K +A    G++T+       +PD+ +  P+
Sbjct: 2023 KDESYEELLRKTKDELLHWTKELTEEEK--KALA--EEGKITIPT----FKPDKIELSPS 2074

Query: 4724 LTP------LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNA 4776
            +        ++   V +G  A F+ ++  K  P  +W + G  I  +        E N  
Sbjct: 2075 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVC 2134

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             L+I +   ED+ +   +A   AG+  + A L+V++K
Sbjct: 2135 ELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 2244 FVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLD 2303
            FV EL+    V E  +   EC V P    N+  ++YHN   L+S  ++ IT   G  +L 
Sbjct: 2269 FVKELQDI-EVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 2304 IQHCVPEDAGEYS 2316
            ++    ED GEYS
Sbjct: 2325 VKDVTKEDQGEYS 2337



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
            L+++E+ E      E     VS   ++ +WYHN+  LKS  ++T T+  G   L +    
Sbjct: 2273 LQDIEVPESYSGELE---CIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVT 2329

Query: 1644 PEDSGTYT 1651
             ED G Y+
Sbjct: 2330 KEDQGEYS 2337



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 64/331 (19%), Positives = 127/331 (38%), Gaps = 35/331 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            K+    +     FE  +  +  PV  W  K   +   +K+ +    +     L+++ I P
Sbjct: 2802 KDVTALENATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVSERKVH--KLMLQNISP 2858

Query: 139  GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
             D GEYT       G+  C   +  E                   + +E     T  +  
Sbjct: 2859 SDAGEYTAVV----GQLECKAKLFVE-----------TLHITKTMKNIEVPETKTASFEC 2903

Query: 199  EQSR-QTQKVAYTNGTDHSSTDDFKV---DTFEYRLLREVSFRESITKRYVGESDVQIST 254
            E S      +   NG +   ++ FK+         ++   S  +S    +V  +D Q+S 
Sbjct: 2904 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND-QVSA 2962

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
             +      V+P  I    ++   +E     F+V ++        W KNG  + +++K ++
Sbjct: 2963 TLT-----VTPIMITSMLKDINAEEKDTITFEVTVNYEGIS-YKWLKNGVEIKSTDKCQM 3016

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
             T     +L +RN    D+  YT +A    G   ++  L VE+    + +  +   + + 
Sbjct: 3017 RTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHIKDIKVLEK 3072

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTE 405
            ++   E   E+SE  +  Q++K  Q+  +T+
Sbjct: 3073 KRAMFE--CEVSEPDITVQWMKDDQELQITD 3101



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            +K++   E     FE  +     P+M   WLKNG  IE S +F  + +     L +++ +
Sbjct: 2888 MKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2944

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTP 730
             +DS EYT       G  +  A L VTP
Sbjct: 2945 TEDSAEYT----FVCGNDQVSATLTVTP 2968



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/158 (22%), Positives = 64/158 (40%), Gaps = 5/158 (3%)

Query: 2926 GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
            GQ + L+  V  +    + + W    +V+ +  + K++   G   L + DV     G YT
Sbjct: 4865 GQTVTLQAAV--RGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYT 4922

Query: 2986 CKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD-DDT 3044
            C A N+ G   +   +       +IER +  + T G      LE ++   P  +P     
Sbjct: 4923 CLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAG--DPATLEYTVAGTPELKPKWYKD 4980

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVI 3082
            GRP   +  ++     +  Q+  Y A L  +G  +  I
Sbjct: 4981 GRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEI 5018



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 19/86 (22%), Positives = 37/86 (43%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E    P  +I W+ +  +L  G ++K       V+L ++     D+G Y C+  N+ G +
Sbjct: 5342 EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 5401

Query: 2996 FTSSTVYCTSKDNLIERTQHPKGTEG 3021
              S+ V      + I++ +      G
Sbjct: 5402 ICSARVTLREPPSFIKKIESTSSLRG 5427



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 4/82 (4%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG-- 718
            E  G P  +I W K+   + +  ++ +  +   +SL +L     D+GEY CR  +  G  
Sbjct: 5342 EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 5401

Query: 719  VAETKAVLHVTPR--ATIERTS 738
            +   +  L   P     IE TS
Sbjct: 5402 ICSARVTLREPPSFIKKIESTS 5423



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/114 (22%), Positives = 57/114 (50%), Gaps = 4/114 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  IT+ ++ +++ ++G     +V+     ++  +W+++G+ L  G +Y+         L
Sbjct: 5505 PATITE-EAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSIL 5563

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEAL 3943
             I+    +DSGEY     ND G    KA I+   + D+I+     + +K+ +++
Sbjct: 5564 KIISTEKKDSGEYTFEVQNDVGRSSCKARIN---VLDLIIPPSFTKKLKKMDSI 5614



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 3/106 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F + L     + +G  I LEC +   G   + ++WF + + ++   ++K  +      
Sbjct: 5602 PSFTKKLKKMDSI-KGSFIDLECIVA--GSHPISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
            L+I      D+G YT  A N  G    S  + V E    V   Q++
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQ 5704



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 18/79 (22%), Positives = 37/79 (46%)

Query: 1725 NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYT 1784
            N     + + +  G   + ++W ++   + +    +   D    +L +      DSGTY 
Sbjct: 5707 NPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYI 5766

Query: 1785 CRAINELGEAVTSSTLFVQ 1803
            C+  N++G A + +TLFV+
Sbjct: 5767 CQLSNDVGTATSKATLFVK 5785



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 18/63 (28%), Positives = 33/63 (52%)

Query: 1607 ATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666
            A + ++W+ +NK L SG+  +   +    +L++ +    DSGTY C+  N +G A +   
Sbjct: 5722 APMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKAT 5781

Query: 1667 AIV 1669
              V
Sbjct: 5782 LFV 5784



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/69 (28%), Positives = 32/69 (46%)

Query: 1876 MRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLN 1935
            M ++W+ + K L SG       D    +L++      DSG Y C+  N++G A S   L 
Sbjct: 5724 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 5783

Query: 1936 VQSKESIIR 1944
            V+     I+
Sbjct: 5784 VKEPPQFIK 5792



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 5/105 (4%)

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
            SIE +  + P FIR L+ + E+ +  +   E ++T    P   V W K+ R I +S + T
Sbjct: 5873 SIELKVKEPPTFIRELKPV-EVVKYSDVELECEVT--GTPPFEVTWLKNNREIRSSKKYT 5929

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
                    +L+I      D G Y     N+ G    + S RVA +
Sbjct: 5930 LTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSC--SCSTRVALK 5972



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/108 (22%), Positives = 46/108 (42%), Gaps = 2/108 (1%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P FT  +  +      + H E ++   G   +  +W ++G  I  S +   +     V+L
Sbjct: 6164 PSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSL 6221

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
             +  +  ED+  YTC+  N  G+   S  L V+   S  ++   + A+
Sbjct: 6222 EVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAI 6269



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 4/130 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F+ +   Q ++ +  T +F+  L   G P  K++WF +   L+   +     +  
Sbjct: 6254 KEPPSFLVKPGRQQAIPD-STVEFKAILK--GTPPFKIKWFKDDVELVSGPKCFIGLEGS 6310

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE 4089
               +N   V    +G+Y C  TN  G D    ++  T  P  V   +  K +K+ +  R 
Sbjct: 6311 TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSR- 6369

Query: 4090 MEASWQVTPE 4099
            +E     +PE
Sbjct: 6370 LECKIAGSPE 6379



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2791 IHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKA 2850
            +  EC  E S  P  ++ W+ + + L S  +YK      + S+ I +    D G Y CKA
Sbjct: 6461 VSLEC--ELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKA 6518

Query: 2851 TNSKGSAT 2858
             N  GS T
Sbjct: 6519 QNEVGSDT 6526



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 19/53 (35%), Positives = 29/53 (54%)

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
            P   V WY + + L+S  +Y+ ++     ++ IL V   D GEY CKA N +G
Sbjct: 6471 PPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 6523



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/61 (36%), Positives = 33/61 (54%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L VEW KDG+ + +S +    F     +L I SV   DAG YT +  N +G+++ +
Sbjct: 6656 GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCT 6715

Query: 997  A 997
            A
Sbjct: 6716 A 6716



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 2/112 (1%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V+V+    P   T+    T    G S   EC++       + V W+     + SG +Y+T
Sbjct: 6718 VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAG--SSPISVAWFHEKTKIVSGAKYQT 6775

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            +       L + ++   D G YTC A N  G       L VQ   S +++ +
Sbjct: 6776 TFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 6827



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 1586 NVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPE 1645
            ++++  G+ A FE  +       +++ W  +NK ++ G  +T T       L I+     
Sbjct: 7206 SIDVIAGESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKG 7263

Query: 1646 DSGTYTCRAINALGEAVTS 1664
            DSG YTC+A N +G+ + S
Sbjct: 7264 DSGQYTCQATNDVGKDMCS 7282



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 3/98 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P FI +L     +  G S   ECR+       + V W+ +G  + SG + ++S       
Sbjct: 7668 PSFIRKLKDVNAIL-GASVVLECRVSG--SAPISVGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            L++  +   D+G YTC A N  G    S  L VQ   S
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPS 7762



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 18/63 (28%), Positives = 33/63 (52%)

Query: 2674 LKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733
            +KI W K+   +  G   K T      TL++  +   D+G YTC A+N+ G+   +A + 
Sbjct: 8168 IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLG 8227

Query: 2734 IED 2736
            +++
Sbjct: 8228 VQE 8230



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 4/77 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P + R LQD+  L+EG+      Q    S P ++ EW+++GR +    R  +        
Sbjct: 9672 PAWERHLQDV-TLKEGQTCTMTCQF---SVPNVKSEWFRNGRILKPQGRHKTEVEHKVHK 9727

Query: 830  LNIMHLRAEDAGSYTVR 846
            L I  +RAED G YT +
Sbjct: 9728 LTIADVRAEDQGQYTCK 9744



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++P  FTK++Q   V EH+ A FE E   +   ++ WY+    +  S  +          
Sbjct: 9758 AEPIQFTKRIQNIVVSEHQSATFECEVSFDD-AIVTWYKGPTELTESQKYNFRNDGRCHY 9816

Query: 4468 LIIRQVFVEDSAVFAAVAE-NRGGTAKCSANLVVEEK 4503
            + I  V  +D  V++ +A     G A+ +A L +  K
Sbjct: 9817 MTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTK 9853



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/106 (25%), Positives = 46/106 (43%)

Query: 245   VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
             +G S+    +E   +  P   P I  +  +  + EG      V     P P V+W K+G+
Sbjct: 15293 IGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGK 15352

Query: 305   RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
              +  S++  +   H    L V  + ++D+G YT+  EN  G    S
Sbjct: 15353 EVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATAS 15398



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 1311  PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
             P      H+I  +EG  + +    + V   T  V W  +GK +K   R     +     L
Sbjct: 15314 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHL 15371

Query: 1371  DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             ++      D+G+YT    N+LG A  S  ++VI
Sbjct: 15372 EVPKSVRADAGIYTITLENKLGSATASINVKVI 15404



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/48 (41%), Positives = 29/48 (60%), Gaps = 1/48 (2%)

Query: 486   EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
             + + APK + R S L V+ G+ + L+A   G+P P ITW KD   I+P
Sbjct: 15603 DPIDAPKVILRTS-LEVKRGDEIALDASISGSPYPTITWIKDENVIVP 15649



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/108 (24%), Positives = 42/108 (38%), Gaps = 4/108 (3%)

Query: 56    GDRQPITAGRPGEPSPPIFEQIFKNA-RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE 114
             G+ QP+T   P EP     +   K   +   G   +    + G P P   WT+++    E
Sbjct: 16015 GETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEG---E 16071

Query: 115   CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
              +K  +  +       L+IK     D G Y  TA N  G    +  ++
Sbjct: 16072 LDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVE 16119



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 10/85 (11%)

Query: 503   REGEPVVLNARAVGTPTPRITWQ---------KDGVPIIPNPELRIHTDGGASTLDIPRA 553
             + G  + + A   G PTP+ +W+         KDGV  IP  + ++ T   +S + IP  
Sbjct: 16750 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPE-DAQLETAENSSVIIIPEC 16808

Query: 554   KASDAAWYQCTAQNVAGSTATRARL 578
             K S    Y  TA+N AG      R+
Sbjct: 16809 KRSHTGKYSITAKNKAGQKTANCRV 16833



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 9/97 (9%)

Query: 776   LQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYK-------DGRPITASSRITSIFNFGYV 828
             L++  E++EG N +  A++  V  PT+   W+K       +  P+   + +  +      
Sbjct: 17049 LKEFMEVEEGTNVNIVAKIKGVPFPTLT--WFKAPPKKPDNKEPVLYDTHVNKLVVDDTC 17106

Query: 829   SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
             +L I   R  D G YT+ AVN LG A     + V  R
Sbjct: 17107 TLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 17143



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 3/73 (4%)

Query: 414   RVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
             R +G+P P+V+WF ++  +  DD  H  +       AL       SDSG    V  N +G
Sbjct: 17768 RYSGKPKPKVSWFKDEADVLEDDRTH--IKTTPATLALEKIKAKRSDSGKYCVVVENSTG 17825

Query: 473   ETAFQCRLNVIEK 485
                  C++NV+++
Sbjct: 17826 SRKGFCQVNVVDR 17838



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/110 (25%), Positives = 44/110 (40%), Gaps = 4/110 (3%)

Query: 378   ETEERIEISEKALAPQF---VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
             +T   IE  EK + P     VK+ +   V  G   RF   + G P P   W  +  +I+ 
Sbjct: 18421 DTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKT 18480

Query: 435   DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
             D  H  +  ++ +  L I N    D+G       N +G       L V++
Sbjct: 18481 D-EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 18529



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 2/76 (2%)

Query: 2926  GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
             GQ + +  +V+ + +PD  I W   GKVL +  R  L  D   V L + +    D G Y 
Sbjct: 18850 GQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 18907

Query: 2986  CKAYNKRGEAFTSSTV 3001
               A N  G A  S+ V
Sbjct: 18908 ISAKNSSGHAQGSAIV 18923



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 2/105 (1%)

Query: 3683  EEITIEDEKPNPPR-FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
             E I  +DE   P       IKD + +  G  +  +  +  +G P  +  W   G+     
Sbjct: 21292 ETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNA-ISILGKPLPKSSWSKAGKDIRPS 21350

Query: 3742  SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
                   +      L I Y   +DAGEYT  ATN +G+     K+T
Sbjct: 21351 DITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVT 21395



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 1735  IPV-GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
             +P+ G PK  + W ++G+P++ + R+          L++K  + +D G Y     N +G+
Sbjct: 24178 VPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 24237

Query: 1794  AVTSSTLFVQSK 1805
                S  +    K
Sbjct: 24238 KTASIEIVTLDK 24249



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P  +  F       G + K E  + G P P +SW +   PL +  + ++   E+T   ++
Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV---EETATSTV 25295

Query: 132   L-IKQIGPGDEGEYTCTARNQYGEA 155
             L IK+    D G+YT TA N  G A
Sbjct: 25296 LHIKEGNKDDFGKYTVTATNSAGTA 25320



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/113 (21%), Positives = 46/113 (40%)

Query: 4391  EHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP 4450
             E    T   +V+  V+P +  +  K      V   E  +   +  G PLP+I W ++   
Sbjct: 26697 EPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIE 26756

Query: 4451  IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
             I+     +I +    ++L ++     D+  +    +N  GT   + N  V +K
Sbjct: 26757 IEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 26809



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 4525  VTSGQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
             V +G++++++  + G +P+ V  W K+G +++   R +I+  D    L + +   +D+G+
Sbjct: 26728 VKAGEVLKINADIAG-RPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQ 26786

Query: 4584  YECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             Y     N AG       C V      DKP P
Sbjct: 26787 YVLTLKNVAGTRSVAVNCKV-----LDKPGP 26812



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 10/120 (8%)

Query: 3943 LTQMEATIKKYTSEVYLTEDD----LYDVDKKQPPR--FVTQIQSQTSLVEMETTKFECQ 3996
            + ++E  I K T E  L ED       D+ + +     F  +I++   L  M  T F C+
Sbjct: 1255 IKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVT-FHCK 1313

Query: 3997 LAPVGDPNMKVEWFFNGKPLLHKNRF-TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            ++  G P  K+ W+ +GK + H  R+       G  ++    V PED G Y   A+N+ G
Sbjct: 1314 MS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1371



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 8/126 (6%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            FT  L ++    +   A FE     T +P +KV+WY +G  +  G ++R   D     L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK-RNIILESQ---LPKGMEGTIDKIAA 3537
            I      D+ +Y C    +     TTA + V+G     + E Q   +P+   G ++ I +
Sbjct: 2233 ILTIDTSDAEDYSCVLVED-ENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVS 2291

Query: 3538 LEGYSG 3543
             E   G
Sbjct: 2292 PENIEG 2297



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 7/89 (7%)

Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIAS 1107
            PLK  N ++EG  A  E +V    D+T +V+WY N +QI   +R+Q         L I  
Sbjct: 2450 PLKDVN-VIEGTKAVLECKVSVP-DVT-SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINR 2506

Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
              A D G Y ++     G  + + +++VE
Sbjct: 2507 THASDEGPYKLI----VGRVETNCNLSVE 2531



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/179 (22%), Positives = 67/179 (37%), Gaps = 13/179 (7%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D +V EG     +C+V+      V W++ND QI+ D   + +V +     L+I     S
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV-KGTKQRLVINRTHAS 2510

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D G    +     G     C L+V   E++   K +     L   E + VV       + 
Sbjct: 2511 DEGPYKLIV----GRVETNCNLSV---EKI---KIIRGLRDLTCTETQNVVFEVELSHSG 2560

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA-QNVAGSTATRA 576
               + W      I P+ + +I   G    L +      D   Y   A +N+     T A
Sbjct: 2561 ID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVA 2618



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 17/51 (33%), Positives = 28/51 (54%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            PP F+S P ++T   G+ A+F C VTG P    +W  +G  +     +K++
Sbjct: 4477 PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKIS 4527



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F T P    +   S+   +        + + + WF   K L++G       +     
Sbjct: 5132 PPSFVTKPGSKDVLPGSAVCLKSTF--QGSTPLTIRWFKGNKELVSGGSCYITKEALESS 5189

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            LE+  V   D+G YTCK +N  G    S  L VK
Sbjct: 5190 LELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 5223



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/116 (22%), Positives = 50/116 (43%), Gaps = 3/116 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI +I+S +        F+  +  K    + + W ++   +      R  ++    S
Sbjct: 5412 PPSFIKKIESTSSLRGGTAAFQATL--KGSLPITVTWLKDSDEITEDDNIRMTFENNVAS 5469

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            L +  +  +  G+Y+C+A ND G     A +S K+ P  I +  V   + + +  T
Sbjct: 5470 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE-PATITEEAVSIDVTQGDPAT 5524



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 2/86 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F +    +  ++ GQ+  F+C++   G P ++V W+ +   I    +   +   G
Sbjct: 5785 KEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFIDG 5842

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
              +  IS  R E+ G Y+C A N  G
Sbjct: 5843 LATFQISGARVENSGTYVCEARNDAG 5868



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/125 (21%), Positives = 54/125 (43%), Gaps = 3/125 (2%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F+ +           V F+  +  K  P  +I+W+++   L SG +     +  
Sbjct: 6253 VKEPPSFLVKPGRQQAIPDSTVEFKAIL--KGTPPFKIKWFKDDVELVSGPKCFIGLEGS 6310

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945
               L++  V A  +G+Y C   ND G D     +   + P  + + +  + +K  ++ ++
Sbjct: 6311 TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDS-SR 6369

Query: 3946 MEATI 3950
            +E  I
Sbjct: 6370 LECKI 6374



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F      V  ++  ++  E  +   G P  ++ W K+ + + +S ++    +  
Sbjct: 6440 VKEPPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNF 6497

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATG 718
            + S+ +L+++  D GEY C+A +  G
Sbjct: 6498 HTSIHILNVDTSDIGEYHCKAQNEVG 6523



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 18/77 (23%), Positives = 36/77 (46%)

Query: 786  RNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTV 845
            +NA    +      P   V WYKD R + +S +        + S++I+++   D G Y  
Sbjct: 6457 KNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHC 6516

Query: 846  RAVNKLGEAISTASIRV 862
            +A N++G      ++++
Sbjct: 6517 KAQNEVGSDTCVCTVKL 6533



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 2130 ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNK 2189
            EC+V   + P +++ WFH   KI +G +Y+TT       L +    + D G Y C A N 
Sbjct: 6747 ECKVAG-SSP-ISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANV 6804

Query: 2190 LG 2191
             G
Sbjct: 6805 AG 6806



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 20/76 (26%), Positives = 33/76 (43%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G S + V W  +   + + ++  T F+     L + S+   D G+YTC A N  G     
Sbjct: 6752 GSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECR 6811

Query: 997  ANLTIVTKKDIIAESQ 1012
            A LT+      + E +
Sbjct: 6812 AVLTVQEPPSFVKEPE 6827



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 2/94 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   P  L +    +  F    +       +V WF   + L+ G R     +     
Sbjct: 6819 PPSFVKEPEPLEVLPGKNVTFTS--VIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 6876

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            LE+  +    +G YTC  +N  G+A+ + +L VK
Sbjct: 6877 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVK 6910



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 5/128 (3%)

Query: 1402 VIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTI--KPRFVTRPKSIENVIEG 1459
            V  +K  ILE  + +  +  QY  +       D+    V+    P FVT  + +E  + G
Sbjct: 6962 VTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAV-G 7020

Query: 1460 QHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTC 1519
              V  +C++    +  + V W+K    +     +R         L    +   DSG YTC
Sbjct: 7021 DSVSLQCQVAGTPE--ITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTC 7078

Query: 1520 RAVNLVGT 1527
            +A N +GT
Sbjct: 7079 KAENSIGT 7086



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +KDI            RL   G   ++V W R+GV +     L T        L
Sbjct: 7102 PSFARQLKDIEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDDENLQTSFVDNVATL 7159

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
             +   +   SG Y+C A N LG A +S+ L
Sbjct: 7160 KILQTDLSHSGQYSCSASNPLGTASSSARL 7189



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G +A FE  +T      MR+ W KD + I      T         L I+ +   D+G YT
Sbjct: 7212 GESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYT 7269

Query: 845  VRAVNKLGEAISTASIRV 862
             +A N +G+ + +A + V
Sbjct: 7270 CQATNDVGKDMCSAQLSV 7287



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F +    +G L+ G +   + +++    P   V W KD + +  S +          S
Sbjct: 7385 PVFTQKPSPVGALK-GSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTS 7441

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIR 861
            L+I++L A D G Y  +A N++G    + S++
Sbjct: 7442 LHILNLEASDVGEYHCKATNEVGSDTCSCSVK 7473



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G++  F+C+V  +    +KI W  +N+ +  G  YK T   +  +L +    + D+G YT
Sbjct: 8153 GESGTFKCHVTGTAP--IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYT 8210

Query: 2848 CKATNSKGSATTSGSL 2863
            C A+N  G  + S  L
Sbjct: 8211 CYASNIAGKDSCSAHL 8226



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P+F +    I+ ++ G   H +C L   G P   V W+++++ +    +     +  
Sbjct: 8323 KEPPIFRKKPHPIETLK-GADVHLECEL--QGTPPFHVSWYKDKRELRSGKKYKIMSENF 8379

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
              S+ I +V   D G Y C+A+N +G
Sbjct: 8380 LTSIHILNVDAADIGEYQCKATNDVG 8405



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 4/104 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFN-GKPLLHKNRFTPIYDF 4028
            K PPRFV ++   +++V  E    + Q    G   + V WF + G+ +   +     Y  
Sbjct: 8416 KAPPRFVKKLSDISTVVGKEV---QLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSE 8472

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                + F  V P ++G+Y C+  N  GM E  A +       IV
Sbjct: 8473 NIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV 8516



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F+  ++D++        F+  +   G   + V W ++G P++ S  + T        L
Sbjct: 8984 PSFSRQLRDVQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNVQTSFLDNTATL 9041

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            N+   +   +G Y+C A N +G A +S+ L +
Sbjct: 9042 NIFKTDRSLAGQYSCTATNPIGSASSSARLIL 9073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG++   E  V  S+  T  + W+ NN  +   +  + T   + + L +      D+G+Y
Sbjct: 9190 EGNSFKLEGRVAGSQPIT--VAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLY 9247

Query: 2847 TCKATNSKGSATTSGSL 2863
            TCK +N  GSA  + S+
Sbjct: 9248 TCKVSNDAGSALCTSSI 9264



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 44/206 (21%), Positives = 75/206 (36%), Gaps = 16/206 (7%)

Query: 365   DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
             D   +Y    + R++  R+ + E  +  + ++  QD     G    F   +  +   EV 
Sbjct: 13814 DDECEYACGVEDRKSRARLFVEE--IPVEIIRPPQDILEAPGADVVFLAELN-KDKVEVQ 13870

Query: 425   WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
             W  N+  +     H+++ +E   H L I ++   D G    +A++K              
Sbjct: 13871 WLRNNMVVVQGDKHQMM-SEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKL-------- 13921

Query: 485   KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
              E   APK       L V  G+P+ +       P     W K+  P+       I T   
Sbjct: 13922 -ELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAE 13977

Query: 545   ASTLDIPRAKASDAAWYQCTAQNVAG 570
              ++  I  AK  D   Y+   QN  G
Sbjct: 13978 QTSFRILEAKKGDKGRYKIVLQNKHG 14003



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 5/112 (4%)

Query: 377   RETEERIEISEKALAPQF---VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR 433
             R TEE I+  +   AP+    VK+     V  G        VTG+P P++TW   D  ++
Sbjct: 14601 RPTEE-IQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 14659

Query: 434   DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
              D     + N      + I +   SD+G     A N  G       +NV++K
Sbjct: 14660 QD-KRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 14710



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 289   LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +SG P P VTW  N + L    +  I TT   +++ ++N Q+S  G Y+LLA+N  G
Sbjct: 17475 VSGKPPPTVTWNMNERTL--PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 17529



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 6/137 (4%)

Query: 2606  IIDQAMRPESWE-QIQLK----EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHV 2660
             ++D+ +  + +E ++Q K    E+   K  E+ V   +Q+ P+    L     +  G  +
Sbjct: 19088 MVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQK-PVLDLKLSGVLTVKAGDTI 19146

Query: 2661  YLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKAT 2720
              LEA V  +  P +     K+   LT   R+K          S+   +  D G Y   AT
Sbjct: 19147 RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTAT 19206

Query: 2721  NLLGEAVSTASIKIEDR 2737
             N  G  V+ A++ + D+
Sbjct: 19207 NTAGSFVAYATVNVLDK 19223



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 7/98 (7%)

Query: 380   EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
             EE++E  +  L  +  K+    ++  G   R    + GRP PEV W   D +IRD     
Sbjct: 23861 EEKLEAPDIDLDLELRKII---NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRD---AA 23914

Query: 440   ILVNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAF 476
             I+   S   +L++ NV   DSG  T    N SG ++AF
Sbjct: 23915 IIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAF 23952



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 9/149 (6%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G + +   L  +AE+  PP F      + + + S    + R+  +   +  V+++ +G  
Sbjct: 87   GQATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAE 143

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            + +    +   +     L I   Y  D+G Y+  ATN  G AT + +L V+G      E 
Sbjct: 144  IQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EE 197

Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIE 3688
            ++P+       S  ++ E+   R E  IE
Sbjct: 198  EVPAKKTKTIVSTAQISESRQTRIEKKIE 226



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/109 (22%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V   T  P F   ++  +++++G     + R+   G  T  V++ +DG  +++S      
Sbjct: 97   VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQIS 153

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                  +L I      D+G Y+  A N++G+AT++A L +  ++++ A+
Sbjct: 154  QEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+S   + +G  V L+ +V     P +K  ++++G  + +    + + +  L +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L I     +DSG Y+  ATN +G A STA + ++
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 58/281 (20%), Positives = 115/281 (40%), Gaps = 19/281 (6%)

Query: 1410 LESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLE 1469
            +ES++    E++ Y    SR K  D    +  +    V+  K  E++   +    E   E
Sbjct: 4207 VESKYLISPEEVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLKPSEEKE-ESSSE 4265

Query: 1470 PVTD--SNLKVEWFKNGQPVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVN--- 1523
              T+  + +K++  + G     G     P+ D      DI+ L    + I   + VN   
Sbjct: 4266 SGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLT---TSITNAKEVNWYF 4322

Query: 1524 ---LVGTDEVSCRLTCRSTTDIVR---STQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
               LV +DE    L  ++T  +V    +T++  G    + L D  K   +  +  V   A
Sbjct: 4323 ENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 4382

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P+    ++ +E+  G  A F   +   S   ++ +W+   + +    + +  ++    +L
Sbjct: 4383 PVIKRKIEPLEVALGHLAKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSL 4440

Query: 1638 DIMSCLPEDSGTYTCRAINALGE-AVTSGIAIVHSKKSIYL 1677
            +I+     D G YTC+A N  G  + T+ + +  +    +L
Sbjct: 4441 EILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFL 4481



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/72 (27%), Positives = 36/72 (50%)

Query: 2667 EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            E ++ PN++ +WFK G  +    +        + +L I   +  D G YTCKA+N  G  
Sbjct: 4405 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 4464

Query: 2727 VSTASIKIEDRH 2738
              TA++ + + +
Sbjct: 4465 SCTATLTVTEAY 4476



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1848 TQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALD 1905
            T L+ P  L+   G++A + C +     P +   W  +G  L     ++ S+      L+
Sbjct: 4479 TFLSRPKSLTTFVGKAAKFICTVTG--TPVIETIWQKDGAALSPSPNWKISDAENKHILE 4536

Query: 1906 ILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH-ESALEKIQYLE 1959
            +  +  +D G Y+CKA N  G  +    L +  K   I++ +  +SA+ K  +LE
Sbjct: 4537 LSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLE 4591



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 4/69 (5%)

Query: 1591 EGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTY 1650
            E  R H + +  PV    ++V W+ NNK L   +            LDI     EDSG+Y
Sbjct: 4680 ESARLHCKLKGSPV----IQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSY 4735

Query: 1651 TCRAINALG 1659
            +C A+N +G
Sbjct: 4736 SCEAVNDVG 4744



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 2/110 (1%)

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQG 2957
            G + SV +    +P  II  A   Q+  G    LE  V     P+LK +WY +G+ L   
Sbjct: 4930 GSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVA--GTPELKPKWYKDGRPLVAS 4987

Query: 2958 SRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
             +++++       L        DSG YT +  N+ G +   +T     +D
Sbjct: 4988 KKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRD 5037



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 2/101 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F+    S   + G  +  ++  +  G   + I W K  + + +           
Sbjct: 5129 VQEPPSFVTKPGSKDVLPGSAVCLKSTFQ--GSTPLTIRWFKGNKELVSGGSCYITKEAL 5186

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
              SL++  +   DSG YTC+  +  G  E  A L V   AT
Sbjct: 5187 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPAT 5227



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/72 (31%), Positives = 35/72 (48%)

Query: 2665 QVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724
            QV+      +  +WFK+G  LT G++ K +    +  L I S    DSG YT +  N +G
Sbjct: 5526 QVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVG 5585

Query: 2725 EAVSTASIKIED 2736
             +   A I + D
Sbjct: 5586 RSSCKARINVLD 5597



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/114 (21%), Positives = 51/114 (44%), Gaps = 2/114 (1%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F   +++       +A F++ +   G P + + WL++   ++  + +       
Sbjct: 5971 LKEPPSFIKKIENTTTVLKSSATFQSTV--AGSPPISITWLKDDQILDEDDNVYISFVDS 6028

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
               L ++ V+   SG YTC+A NE G     + L VQ  A +  +++     +K
Sbjct: 6029 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEK 6082



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 77/395 (19%), Positives = 143/395 (36%), Gaps = 30/395 (7%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P F++ + N   V +        +    G P + + W  + + +         +   
Sbjct: 5972 KEPPSFIKKIENTTTVLKSSATF---QSTVAGSPPISITWLKDDQILDEDDNVYISFVDS 6028

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQL-LE 1292
               L I    +  +G YT +A N  G     A + V E + IV   ++    E+  + LE
Sbjct: 6029 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLE 6088

Query: 1293 DAARRT-----KQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVE-- 1345
                 T     K +++   ++ +  FS +  N   V    +    + Q  G  T +VE  
Sbjct: 6089 CVVAGTPELKVKWLKDGKQIVPSRYFSMSFEN--NVASFRIQSVMK-QDSGQYTFKVEND 6145

Query: 1346 ---WFCNGKPIKTGHRFRPAYEFDYVALDLL---SVYPE----DSGVYTCQATNQLGEAV 1395
                 C+           P++      +D +   S++ E     S   + Q      E  
Sbjct: 6146 FGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIS 6205

Query: 1396 TSCALRVIA-KKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIK--PRFVTRPKS 1452
            TS   R++  ++ + LE  +    +   Y    S     D     +T+K  P F+ +P  
Sbjct: 6206 TSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGR 6265

Query: 1453 IENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
             +  I    V F+  L+       K++WFK+   +  G +     +     L++  + A 
Sbjct: 6266 -QQAIPDSTVEFKAILKGTPP--FKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDAS 6322

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
             +G YTC   N VG+D  +  L        V+  +
Sbjct: 6323 KTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLE 6357



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 2/86 (2%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            +  P  + E   +  V E      EC V     P L++++  +GK +  +  F ++F+  
Sbjct: 6064 VQEPAQIVEKAKSVDVTEKDPMTLECVVAGT--PELKVKWLKDGKQIVPSRYFSMSFENN 6121

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALG 2324
              S  IQ  + +D+G+Y+ K  N  G
Sbjct: 6122 VASFRIQSVMKQDSGQYTFKVENDFG 6147



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/96 (20%), Positives = 45/96 (46%), Gaps = 2/96 (2%)

Query: 767  SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG 826
            ++ P+F++ L+    ++ G ++  E ++     P +RV W+++   + AS +    F   
Sbjct: 6347 TEPPKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDS 6404

Query: 827  YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               + + +L  ED+G +   A N  G    +  + V
Sbjct: 6405 VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIV 6440



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 11/145 (7%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F +      +L   E +  EC+L+  G P  +V W+ + + L    ++       
Sbjct: 6441 KEPPVFSSFPPIVETLKNAEVS-LECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNF 6497

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD-------SQLPKHMK 4082
            + +++   V   D GEY C+A N  G D     +K    P  V         +  P  ++
Sbjct: 6498 HTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQ 6557

Query: 4083 -SIEKIREMEASWQVTPEQVVEESK 4106
             SIE  + +   W    E+V+ ES+
Sbjct: 6558 ASIEGAQPIFVQWLKEKEEVIRESE 6582



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            GE    E ++  T  P L VEWY +GK L +  + +         L I     +D+G Y 
Sbjct: 6645 GETCTLECKVAGT--PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 6702

Query: 3495 CRAYNNYGEAVTTASMKVQGK 3515
             +  NN G++  TA + V  +
Sbjct: 6703 FQVQNNVGKSSCTAVVDVSDR 6723



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 3/109 (2%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F    + + V   +   F +  +  G P  +V W R    +   +R     +  
Sbjct: 6816 VQEPPSFVKEPEPLEVLPGKNVTFTS--VIRGTPPFKVNWFRGARELVKGDRCNIYFEDT 6873

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS-LQLESQH 1814
               L +  ++   SG YTC   N  G+A  ++ LFV+  A+ L+  S H
Sbjct: 6874 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDH 6922



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 3/91 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P FV  P+ +E V+ G++V F   +        KV WF+  + +  G R     +     
Sbjct: 6820 PSFVKEPEPLE-VLPGKNVTFTSVIRGTPP--FKVNWFRGARELVKGDRCNIYFEDTVAE 6876

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L++ ++    SG YTC   N  G    + RL
Sbjct: 6877 LELFNIDISQSGEYTCVVSNNAGQASCTTRL 6907



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/98 (22%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            +E P F   ++  E   G  V L+  +     P + V WY     ++    ++T +    
Sbjct: 7003 LEPPYFVTELEPLEAAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTNNV 7060

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
              L        D+G Y CKA N++G A + +  ++  +
Sbjct: 7061 ATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 7098



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F +   S+  + G    FE  +   G   M+I W K+ + I     +T         L
Sbjct: 7198 PFFDIKPVSIDVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHL 7255

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +L +   DSG+YTC+A +  G     A L V
Sbjct: 7256 RILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 7287



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)

Query: 3294 LVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSG 3353
            ++ G+SA FE  +       +++ W  + K++  G  Y          L IL   + +SG
Sbjct: 7209 VIAGESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSG 7266

Query: 3354 EYECVATNKLGRDSTKANL 3372
            +Y C ATN +G+D   A L
Sbjct: 7267 QYTCQATNDVGKDMCSAQL 7285



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            PVFTQ    +  ++ G      C +   G P  +V W ++ K + +S +   T      S
Sbjct: 7385 PVFTQKPSPVGALK-GSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTS 7441

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I ++   D G Y C+A+N +G
Sbjct: 7442 LHILNLEASDVGEYHCKATNEVG 7464



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/85 (28%), Positives = 32/85 (37%), Gaps = 2/85 (2%)

Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGF 1634
            T  P  T  LK      G     E ++       + V W+H    + SG ++  T     
Sbjct: 8606 TVPPSFTRKLKETNGLSGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNT 8663

Query: 1635 VALDIMSCLPEDSGTYTCRAINALG 1659
             AL +      DSG YTC A N  G
Sbjct: 8664 CALTVNMLEESDSGDYTCIATNMAG 8688



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 2504 EFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF 2563
            E + P F  +   P +   G+ A +E  V   G   ++  W  +  E++ G +++ ++  
Sbjct: 9075 EGKNPPFFDIRLAPVDAVVGESADFECHVT--GTQPIKVSWAKDSREIRSGGKYQISYLE 9132

Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590
                L +  V   D+G Y C A+N  G
Sbjct: 9133 NSAHLTVLKVDKGDSGQYTCYAVNEVG 9159



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 39/156 (25%), Positives = 60/156 (38%), Gaps = 9/156 (5%)

Query: 1056 VEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGV 1115
            V G+SA FE  V     +   V W  + ++I S  + Q  +      L +  V   DSG 
Sbjct: 9092 VVGESADFECHVTGTQPIK--VSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQ 9149

Query: 1116 YTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF-----VEPMYQIE 1170
            YT  A N  G+   +A + ++ R  +   S  + L E     E + F     V     I 
Sbjct: 9150 YTCYAVNEVGKDSCTAQLNIKER--LIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPIT 9207

Query: 1171 EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGD 1206
                   + +QP SN     +   + L+ R   M D
Sbjct: 9208 VAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMND 9243



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 7/125 (5%)

Query: 1933 RLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRA----VQDDSFVVEKPQFGKPIKNAE 1988
            +L    K  I  D    +   K   L+D   Y+      +      V +P + + +++  
Sbjct: 9623 KLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVT 9682

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            + EG    +    +    P ++ EW+ NGR ++   R KT  +     L I    AED G
Sbjct: 9683 LKEGQTCTMTCQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQG 9739

Query: 2049 TYMCK 2053
             Y CK
Sbjct: 9740 QYTCK 9744



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 3/65 (4%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            LKEG      C+    + P++  +WF NG+ ++   R++T  +     L I    AED G
Sbjct: 9683 LKEGQTCTMTCQ---FSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQG 9739

Query: 2181 TYMCK 2185
             Y CK
Sbjct: 9740 QYTCK 9744



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 7/126 (5%)

Query: 1689 NQLEDTSKYQRHSAQDEVITQA-PV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +Q + T KY+      E+  +A P+ FT  +++I V+E+Q+A FE     V      V W
Sbjct: 9737 DQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECE---VSFDDAIVTW 9793

Query: 1747 LRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRA-INELGEAVTSSTLFVQSK 1805
             +    +  S +    +D     + +  V P+D G Y+  A +   GEA +++ L++ +K
Sbjct: 9794 YKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTK 9853

Query: 1806 ASLQLE 1811
              ++LE
Sbjct: 9854 -EIKLE 9858



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 8/112 (7%)

Query: 1042  KPRFLG---PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
             KPR +G   PLK    +  G++A F+  +  +    + VEWY  GK++  ++++    + 
Sbjct: 13119 KPRVIGLLRPLKDVT-VTAGETATFDCELSYED---IPVEWYLKGKKLEPSDKVVPRSEG 13174

Query: 1099  GYVALDIASVRAEDSGVYTVVARNAAGEAQLSA-SMTVETRSSIDTSSIHRG 1149
                 L +  V+ ED+G   + A++    A L      VE    ++  ++  G
Sbjct: 13175 KVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEG 13226



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 19/65 (29%), Positives = 32/65 (49%)

Query: 2139  PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
             P  T+ W  +G++++A  R    +D     L++  +   D+G Y     NKLG A  +  
Sbjct: 15341 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 15400

Query: 2199  LKVAG 2203
             +KV G
Sbjct: 15401 VKVIG 15405



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             GQ + + A+V+ R +P+  I W K G  L    R+    D   V L I      D G Y 
Sbjct: 18850 GQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 18907

Query: 2717  CKATNLLGEAVSTASIKIEDR 2737
               A N  G A  +A + + DR
Sbjct: 18908 ISAKNSSGHAQGSAIVNVLDR 18928



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 4/122 (3%)

Query: 4091  EASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWL--LNG 4148
             E+ W  T E VV+E   + P + + L   +TV+ G+  R    V G P P V W    + 
Sbjct: 19110 ESDWVKTEEVVVKEDLQK-PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDA 19168

Query: 4149  NTIVNGSRYKL-TYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR 4207
               +    R K+ T      F + K ++ D GK  V              + V+ +    R
Sbjct: 19169 TDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVR 19228

Query: 4208  GV 4209
              +
Sbjct: 19229 NL 19230



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 31/149 (20%), Positives = 66/149 (44%), Gaps = 9/149 (6%)

Query: 631   DRVYPPPQFIVPLKSVTAMEGG-KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
             + V P     V +KS+  ++ G  +  +  +   G P   + W K+G  ++ +       
Sbjct: 20216 ENVPPRIDLSVAMKSLLTVKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAM 20273

Query: 690   RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT----PRATIERTSQHPE--T 743
             +    +L++ S+N +DSG+YT  A +++G       L V     P A+++    + +   
Sbjct: 20274 QRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAM 20333

Query: 744   LQYIQQLEDYSKYQHQESIEEQTSQRPQF 772
             L +   LED         ++++ + RP +
Sbjct: 20334 LSWEPPLEDGGSEITNYIVDKRETSRPNW 20362



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/99 (22%), Positives = 43/99 (43%), Gaps = 4/99 (4%)

Query: 3047  PP--EFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
             PP  + +   K ++ +  G     +A++   G     + W  +G  ++ +  I+      
Sbjct: 20219 PPRIDLSVAMKSLLTVKAGTNVCLDATVF--GKPMPTVSWKKDGTLLKPAEGIKMAMQRN 20276

Query: 3105  MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
             +  LE+      DSG Y+  A N  G    ++KL+ +DK
Sbjct: 20277 LCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 20315



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 1/93 (1%)

Query: 773   IRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNI 832
             ++ L DL  L +  N++F  ++     P   V W K   P+   +R++   +    +L +
Sbjct: 20911 LKGLPDLCYLAK-ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIV 20969

Query: 833   MHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
                +  DAG YT+   N  G    T SI+V  +
Sbjct: 20970 YDCQKSDAGKYTITLKNVAGTKEGTISIKVVGK 21002



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 7/102 (6%)

Query: 472   GETAFQCRLNVIEKEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
             GE A    + ++E+E  +AP F    E   TL VR G  + +     G P P +TW KD 
Sbjct: 21684 GEPAVIPDVEIVERE--MAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN 21741

Query: 529   VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             + +       I      + L IP     D   +  T +N AG
Sbjct: 21742 INL--KNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 21781



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/156 (23%), Positives = 68/156 (43%), Gaps = 13/156 (8%)

Query: 4548  LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             L NG+ ++ +  N ILE + T + L  +A    + ++  +A N+AG     +E   ++  
Sbjct: 22325 LPNGRWLKANFSN-ILENEFTVSGLTEDA----AYEFRVIAKNAAGAISPPSEPSDAITC 22379

Query: 4608  TKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
               D   P+ K       +    KD ++ + G+A      + G+P PT++W K  K ++ +
Sbjct: 22380 RDDVEAPKIK-------VDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGT 22432

Query: 4667  KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                ++        L   ++   D G Y   A N  G
Sbjct: 22433 AKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 22468



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 50/195 (25%), Positives = 81/195 (41%), Gaps = 17/195 (8%)

Query: 3042  DDTGRPPEFTTV-FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
             DD   P     V FKD V +  G+    EA +  +G     +EW  +GK +E + ++   
Sbjct: 22381 DDVEAPKIKVDVKFKDTVILKAGEAFRLEADV--SGRPPPTMEWSKDGKELEGTAKLEIK 22438

Query: 3101  YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK-SKGQKPRFTTHIQNIE 3159
              A     L    +   DSG Y+  ATN  G A+    ++ +D+    + P   T + + +
Sbjct: 22439 IADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 22498

Query: 3160  GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV-VLDIAYTQNHD 3218
              +             P+DD   KI+  H     R ++R+   +    V V  +  T+   
Sbjct: 22499 CVLS--------WFPPLDDGGAKID--HYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 22548

Query: 3219  SGEYVCR--AYNKYG 3231
               EY+ R  A NKYG
Sbjct: 22549 GNEYIFRVMAVNKYG 22563



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/92 (28%), Positives = 42/92 (45%)

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            +GE   +++T    +   V   KI +  +N  + E  DA F V+L+      V W KNG 
Sbjct: 2686 IGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV 2745

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L ++ K+ I       +LR++N    D   Y
Sbjct: 2746 VLESNEKYAISVKGTIYSLRIKNCAIVDESVY 2777



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KDI+V E + A FE     V +P + V+W+++   ++ ++R+    +     L +
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLI 3116

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                  D+G YT  A    G  V+++ LFV+ +
Sbjct: 3117 PSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3145



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 10/129 (7%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F++RPKS+   + G+   F C +       ++  W K+G  ++    ++         
Sbjct: 4478 PTFLSRPKSLTTFV-GKAAKFICTVTGTPV--IETIWQKDGAALSPSPNWKISDAENKHI 4534

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L++ +L  +D G+Y+C+A N  G D       C++   I+        LE +Q   ++ K
Sbjct: 4535 LELSNLTIQDRGVYSCKASNKFGAD------ICQAELIIIDKPHFIKELEPVQSAINK-K 4587

Query: 1564 YHRTDMVDE 1572
             H    VDE
Sbjct: 4588 VHLECQVDE 4596



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 2/74 (2%)

Query: 928  HFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAY 987
            H E +++   D  + V W KDG+ +         F      L I    + D+G Y C A 
Sbjct: 4589 HLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTAS 4646

Query: 988  NAIGQATTSANLTI 1001
            N  G ++ SA +T+
Sbjct: 4647 NEAGSSSCSATVTV 4660



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F + +     +  G+ A    ++   G P ++  W+ N  EL   +  R       
Sbjct: 4662 EPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSE 4719

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
              LDI  V   D+G Y C+A+N  G
Sbjct: 4720 AILDITDVKVEDSGSYSCEAVNDVG 4744



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 15/59 (25%), Positives = 33/59 (55%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            +++ W+ +GK +    R+++    G  +L+++ V   D+G +TC+A N  G   +S  +
Sbjct: 5069 MRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL 5127



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 3/117 (2%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            VA+ + P FI ++   T + +  SA ++  +     P + + W  + ++L        S 
Sbjct: 5969 VALKEPPSFIKKIENTTTVLKS-SATFQSTVAG--SPPISITWLKDDQILDEDDNVYISF 6025

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
                A L I +V    SG YTC+A N  G       L VQ    I+  ++     EK
Sbjct: 6026 VDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEK 6082



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 3/113 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   I++  ++ +   A F++ +   G   + + WLKD + ++    +   F    
Sbjct: 5973 EPPSFIKKIENTTTVLKSS-ATFQSTVA--GSPPISITWLKDDQILDEDDNVYISFVDSV 6029

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEK 1019
              L I+SV    +G YTC+A N  G     A L +     I+ +++     EK
Sbjct: 6030 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEK 6082



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query: 4110 PPVFVS-LPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            PP FV  L  +  V+ G+ +R  C++ G P+ RV+W  N + +    +Y++T+
Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF 6401



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            + E    P  ++ WY + + L    ++K+ S     ++ +++V   D G Y CKA N+ G
Sbjct: 6464 ECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 6523

Query: 2994 EAFTSSTVYCTSK 3006
                S T  CT K
Sbjct: 6524 ----SDTCVCTVK 6532



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 2/71 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+    EC V  +  P L +EW+ + K L S  ++K +      SL I     +D+G YT
Sbjct: 6645 GETCTLECKVAGT--PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 6702

Query: 2848 CKATNSKGSAT 2858
             +  N+ G ++
Sbjct: 6703 FQVQNNVGKSS 6713



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 17/55 (30%), Positives = 29/55 (52%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G   +   W+    ++  G++++TT      TL +NS+ ++D G Y C A N AG
Sbjct: 6752 GSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAG 6806



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 3/93 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F++  + L E+  G+N  F + +     P  +V W++  R +    R    F      
Sbjct: 6820 PSFVKEPEPL-EVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 6876

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            L + ++    +G YT    N  G+A  T  + V
Sbjct: 6877 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 6909



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 2/79 (2%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            G+N  F + +  T  P  KV W+   + L  G R   + +     LE+       SGEY 
Sbjct: 6834 GKNVTFTSVIRGT--PPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 6891

Query: 3495 CRAYNNYGEAVTTASMKVQ 3513
            C   NN G+A  T  + V+
Sbjct: 6892 CVVSNNAGQASCTTRLFVK 6910



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            + P F  + K IE  + G  V   C+L     + ++V W+++G  +      +       
Sbjct: 7100 LPPSFARQLKDIEQTV-GLPVTLTCRLNG--SAPIQVCWYRDGVLLRDDENLQTSFVDNV 7156

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
              L I+      SG Y+C A N +GT   S RLT R
Sbjct: 7157 ATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 7192



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   LK +    G  +    R+   G   +++ W ++G  +       + F     +
Sbjct: 7101 PPSFARQLKDIEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDDENLQTSFVDNVAT 7158

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVL 726
            L +L  ++  SG+Y+C A +  G A + A L
Sbjct: 7159 LKILQTDLSHSGQYSCSASNPLGTASSSARL 7189



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            + P R + +    T V  G     EC V     P L  +++ +G+ L + ++ HITF   
Sbjct: 7569 LEPARIIEKPEPMT-VTTGNPFALECVVTGT--PELSAKWFKDGRELSADSKHHITFINK 7625

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
              SL I      D G YS +  N++G     +S+ V+
Sbjct: 7626 VASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVS 7662



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP FI  ++ V  ++ G+ A  + ++     P++++ W+    KL     Y+      +
Sbjct: 7945 EPPYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNNV 8001

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L I      + GEY C A N +G  ++ A L
Sbjct: 8002 ASLVINKVDHSDVGEYSCKADNSVGAVASSAVL 8034



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 3/94 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P FT  L     L  G +   E ++  +  P + V W+  G  + +G +++T        
Sbjct: 8609 PSFTRKLKETNGL-SGSSVVMECKVYGS--PPISVSWFHEGNEISSGRKYQTTLTDNTCA 8665

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            L ++     DSG+Y C A N  G    +A + V+
Sbjct: 8666 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVR 8699



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P     L  V+   G+ A FE  +       +KV W  +++ ++SG ++  +       L
Sbjct: 9080 PFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHL 9137

Query: 1638 DIMSCLPEDSGTYTCRAINALGE 1660
             ++     DSG YTC A+N +G+
Sbjct: 9138 TVLKVDKGDSGQYTCYAVNEVGK 9160



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/177 (21%), Positives = 73/177 (41%), Gaps = 14/177 (7%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            + EG+   + C+      P ++ EWF NGR +    R KT  +     L I    + D G
Sbjct: 9683 LKEGQTCTMTCQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQG 9739

Query: 1249 EYTVRAVNHLGSAH---TSAIVRVIERSDIVTDTQNEQAIEQIQL-LEDAARRTKQVRED 1304
            +YT +  +   SA     +  ++  +R   +  ++++ A  + ++  +DA     +   +
Sbjct: 9740 QYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTE 9799

Query: 1305 ITVMQAPQFSR-------ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            +T  Q   F          +HN+   +     +  RL+P G+     E +   K IK
Sbjct: 9800 LTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIK 9856



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 5/89 (5%)

Query: 4727  LRDIVVYE----GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782
             ++DI++ E    G  A F+  ++     T  W+++G+ I E+P  + I +G +  L I +
Sbjct: 12048 IKDIILTESEFVGSSAIFECLVSPSTAITT-WMKDGSNIRESPKHRFIADGKDRKLHIID 12106

Query: 4783  TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                 D G +TC       +  ++AKLVV+
Sbjct: 12107 VQLSDAGEYTCVLRLGNKEKTSTAKLVVE 12135



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 40/181 (22%), Positives = 75/181 (41%), Gaps = 18/181 (9%)

Query: 3047  PP--EFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
             PP  EF     D+  + E ++A +E  L     ++  ++WF +G  I+   +   +    
Sbjct: 13298 PPHVEFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGA 13353

Query: 3105  MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
             + +L I      D   YSC          ++V LE       ++  FT ++ NIE + + 
Sbjct: 13354 VRILVINKCLLDDEAEYSCEVRTARTSGMLTV-LE-------EEAVFTKNLANIE-VSET 13404

Query: 3165  QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              +    C V     P  ++ WY   + +  + R + +++    +L I      D+G Y C
Sbjct: 13405 DTIKLVCEV---SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 13461

Query: 3225  R 3225
             R
Sbjct: 13462 R 13462



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/102 (33%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 4079  KHMKSIEKIR-EMEASWQVTPEQ---VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRV 4134
             KHM +I+      E  + VT  Q   V E      P  FV   +  TV E + A F C++
Sbjct: 13714 KHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQL 13773

Query: 4135  TGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYD 4176
             +   K  V W  NG  I  G +YK   DG  H  I K  + D
Sbjct: 13774 S-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 13814



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 266   PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
             PKI    ++  +  G      V     P+    WFK  + L  S K  I TT   T+ R+
Sbjct: 13927 PKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPL--STK-TIDTTAEQTSFRI 13983

Query: 326   RNTQKSDSGHYTLLAENPNG 345
                +K D G Y ++ +N +G
Sbjct: 13984 LEAKKGDKGRYKIVLQNKHG 14003



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 10/100 (10%)

Query: 392   PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF--------INDRQIRDDYNHKILVN 443
             P  + + +  +V EG       ++ G P+P +TWF          +  + D + +K++V+
Sbjct: 17044 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 17103

Query: 444   ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             ++    L+I     SD+G+ T  A N  G  + + RLNV+
Sbjct: 17104 DT--CTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVL 17141



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 501   NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             +++ G+ + L+A   G P P++TW+K+     P  + RI      S L+I  A   D   
Sbjct: 18156 HIKVGDTLRLSAIIKGVPFPKVTWKKEDRD-APT-KARIDVTPVGSKLEIRNAAHEDGGI 18213

Query: 561   YQCTAQNVAGSTATRARL 578
             Y  T +N AGS     ++
Sbjct: 18214 YSLTVENPAGSKTVSVKV 18231



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 6/119 (5%)

Query: 371   ITDTQQRETEERIEISEKALAPQFVKV---CQDR-DVTEGKMTRFDCRVTGRPYPEVTWF 426
             + + + RE  E + I++  L P  V++   C+D   V  G+  R   RV GRP P++TW 
Sbjct: 18812 VGEGEPRELAESV-IAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITW- 18869

Query: 427   INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
               + ++        L+ +     L I     +D G     A+N SG       +NV+++
Sbjct: 18870 TKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDR 18928



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 286   QVQLSGNPRPRVTWFKNGQRLINSN-KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPN 344
             +  + G P P V W K+G+ L  +  + EI +T   TTL V++  ++D G Y L   N  
Sbjct: 25655 EADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVG 25714

Query: 345   G 345
             G
Sbjct: 25715 G 25715



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 17/77 (22%), Positives = 35/77 (45%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  R +    G P+P + W+++   I+   + +I      + L +R    +   V+   A
Sbjct: 28901 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 28960

Query: 4486  ENRGGTAKCSANLVVEE 4502
             +N  G+AK    + V++
Sbjct: 28961 KNASGSAKAEIKVKVQD 28977



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 19/163 (11%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSG 3119
            +E Q   +E  L  +G   + + W +  K I+ S + + + A G +  L +L     D G
Sbjct: 2545 TETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEG 2600

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             Y+  A       +++V    + K    +            + + Q A FEC V    +P
Sbjct: 2601 KYTFYAGENITSGKLTVAGGAISKPLTDQT-----------VAESQEAVFECEVA---NP 2646

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            D K EW  +G+ +  +  I++ SD     L IA T+  D GEY
Sbjct: 2647 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY 2689



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 8/94 (8%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            F  H+K   K++E +    E +V   ++P++ ++W K+   L    R+K   +  +  L 
Sbjct: 3060 FRKHIKDI-KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLL 3115

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            I S R  D+G YT  A    G  VSTA + +E R
Sbjct: 3116 IPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3145



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            K++E + A FE  V   S+  +TV+W  + +++   +RI+   +     L I S R  D+
Sbjct: 3068 KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3124

Query: 1114 GVYTVVARNAAGEAQL 1129
            G YTVVA      A+L
Sbjct: 3125 GKYTVVAGGNVSTAKL 3140



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAED-SGVYTVVARNAAGEAQLSASMTV 1135
            V WYF  K + S  + +   D     L I  V  ED  G Y   A N +G+   SA +TV
Sbjct: 4318 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4377

Query: 1136 ETRSS 1140
              R++
Sbjct: 4378 VKRAA 4382



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 19/66 (28%), Positives = 32/66 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P LK +W+K+G  L    + + +F   +  L   S    DSG YT + +N +G +    +
Sbjct: 4971 PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 5030

Query: 2732 IKIEDR 2737
              + DR
Sbjct: 5031 FTVLDR 5036



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/83 (25%), Positives = 35/83 (42%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G   L + W +    + +        +    +L +  V   DSGTYTC+  N  G    S
Sbjct: 5158 GSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECS 5217

Query: 1798 STLFVQSKASLQLESQHESALQK 1820
            + LFV+  A+   + +    L+K
Sbjct: 5218 ANLFVKEPATFVEKLEPSQLLKK 5240



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/66 (31%), Positives = 30/66 (45%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P +++ W  N   I+ S++           L +  V  EDSG Y C A NE G    S
Sbjct: 5252 GTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS 5311

Query: 1798 STLFVQ 1803
            S + V+
Sbjct: 5312 SIVIVK 5317



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 7/131 (5%)

Query: 1538 STTDIVRSTQNEAGLEQIQVLED--RSKYH-RTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
            S   I+ + + ++G    +V  D  RS    R +++D +    P  T  LK ++  +G  
Sbjct: 5561 SILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIP--PSFTKKLKKMDSIKGSF 5618

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
               E   I      + ++W+ +++ + +  ++  + +     L+I      DSGTYTC A
Sbjct: 5619 IDLE--CIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSA 5676

Query: 1655 INALGEAVTSG 1665
             N  G    SG
Sbjct: 5677 TNKAGHNQCSG 5687



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F + L+ ++ ++       +C +   G P  +V W +N + I  S + T T    
Sbjct: 5879 KEPPTFIRELKPVEVVKYSDV-ELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTDRVS 5935

Query: 2433 YVSMTISHVRDEDEGVYMCRASN 2455
              ++ I+     D G Y C  SN
Sbjct: 5936 VFNLHITKCDPSDTGEYQCIVSN 5958



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G+T   +C++   G P L VEW+++ KL+  S +   +      S+ I  V  +D G Y 
Sbjct: 6645 GETCTLECKV--AGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 6702

Query: 2451 CRASNLLGE 2459
             +  N +G+
Sbjct: 6703 FQVQNNVGK 6711



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 5/115 (4%)

Query: 1174 KSKPVF-VQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            K  P F ++P+S    V  G++   EC +   G   MR+ W  + + +  G  +      
Sbjct: 7195 KKSPFFDIKPVSID--VIAGESADFECHVT--GAQPMRITWSKDNKEIRPGGNYTITCVG 7250

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQ 1287
                L I+     D+G+YT +A N +G    SA + V E    V   +  +  +Q
Sbjct: 7251 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQ 7305



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ 1093
            E  V + + P F+ PL+    ++ G+ A  + +V+   ++   + WY    ++ SA   +
Sbjct: 7938 EALVSVLEPPYFIEPLEHVEAVI-GEPATLQCKVDGTPEIR--ISWYKEHTKLRSAPAYK 7994

Query: 1094 TYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
                    +L I  V   D G Y+  A N+ G    SA + ++ R
Sbjct: 7995 MQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKER 8039



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/55 (32%), Positives = 25/55 (45%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P +R  WY    +L+    ++        +L IN V  +D G Y CKA N  G
Sbjct: 7972 GTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVG 8026



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P F + L +      G  +  ECR+   G   ++V W+ +G  +   +  +T +   
Sbjct: 8040 KLPPFFARKLKDVHETL-GFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHN 8096

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
               L I+    +  G+Y   A N LG+A +SA
Sbjct: 8097 VATLQILQTDQSHIGQYNCSASNPLGTASSSA 8128



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSS-MRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F     D+  +      FECR   +N S  ++V W+ +G  L   + ++T       
Sbjct: 8042 PPFFARKLKDVHETLGFPVAFECR---INGSEPLQVSWYKDGVLLKDDANLQTSFVHNVA 8098

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
             L+I    Q   G Y C A+N  G A+ S KL
Sbjct: 8099 TLQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 1/87 (1%)

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            +++ W  + R ++ G  +K T       L +L     D G Y C A+N  G+   ++ + 
Sbjct: 8168 IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLG 8227

Query: 2069 VDAKSGLYLDTLDEQRLKKIQELEKYE 2095
            V  +   ++  L+  R+ K  E  +YE
Sbjct: 8228 VQ-EPPRFIKKLEPSRIVKQDEFTRYE 8253



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 19/86 (22%), Positives = 37/86 (43%), Gaps = 2/86 (2%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P+F      I   +    H E  L   G P   V W ++   + +  +   M +  
Sbjct: 8322 VKEPPIFRKKPHPIETLKGADVHLECEL--QGTPPFHVSWYKDKRELRSGKKYKIMSENF 8379

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELG 1792
              ++++  V+  D G Y C+A N++G
Sbjct: 8380 LTSIHILNVDAADIGEYQCKATNDVG 8405



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 2/83 (2%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            I   +G   H E  L+  G     V W KD R + +  +          ++ I +V   D
Sbjct: 8335 IETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAAD 8392

Query: 979  AGHYTCRAYNAIGQATTSANLTI 1001
             G Y C+A N +G  T   ++ +
Sbjct: 8393 IGEYQCKATNDVGSDTCVGSIAL 8415



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/96 (23%), Positives = 39/96 (40%), Gaps = 2/96 (2%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P  + +      +   +T   EC +A  G P +  +WF +GK L   N++   +      
Sbjct: 8512 PATIVEKPESIKVTTGDTCTLECTVA--GTPELSTKWFKDGKELTSDNKYKISFFNKVSG 8569

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
            +    V P DSG Y     N  G D   A ++ + +
Sbjct: 8570 LKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 8605



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 4105 SKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DG 4163
            ++ + PP F      V    GE A F C VTG    +V W  +   I +G +Y+++Y + 
Sbjct: 9074 TEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN 9133

Query: 4164 MYHFDIPKTRQYDTGK 4179
              H  + K  + D+G+
Sbjct: 9134 SAHLTVLKVDKGDSGQ 9149



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S+P +R++W K GR I  S R +  F  G   L +  +   D+G Y  +A N  G   + 
Sbjct: 9299 SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTK 9357

Query: 858  ASIRVAARSTV 868
            + + +  +  V
Sbjct: 9358 SKVTIKDKPAV 9368



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 9/126 (7%)

Query: 1859  GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
             G SA +EC + P         W  +G  ++   ++R   D     L I+ V   D+GEYT
Sbjct: 12060 GSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 12116

Query: 1919  CKAINNLGQAVSSIRLNVQS-KESIIRDSQHESALEKIQ--YLEDDSRYKRAV---QDDS 1972
             C       +  S+ +L V+      ++  + E  + K Q  YL  +   +R V   +D  
Sbjct: 12117 CVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGK 12176

Query: 1973  FVVEKP 1978
              VVEKP
Sbjct: 12177 IVVEKP 12182



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 8/122 (6%)

Query: 2336  AKGSIISESQRPEGLEKIRELE-SAEPFKRPEIPEPVTRQRPV-FTQPLQNIDNIQEGQT 2393
             ++G + + + R   LE   E++ +A+ FK         ++ PV FT+PL++   ++EG T
Sbjct: 13172 SEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHA--NLFVKEPPVEFTKPLED-QTVEEGAT 13228

Query: 2394  AHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453
             A  +C    V     KV+WF+N   I  S +     D     + I     ED   Y C A
Sbjct: 13229 AVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 13285

Query: 2454  SN 2455
              +
Sbjct: 13286 KD 13287



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 61/307 (19%), Positives = 115/307 (37%), Gaps = 47/307 (15%)

Query: 273   RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
             ++++++E  +  F  +++     +  WF+N + + +S+K+ I+      TLR+R+    D
Sbjct: 13574 KDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDD 13632

Query: 333   SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
               +Y +   N  G         V+S     V+++  + +   +  ET E+          
Sbjct: 13633 QANYNVSLTNHRG-------ENVKSAANLIVEEEDLRIVEPLKDIETMEK---------- 13675

Query: 393   QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
                           K   F C+V  R    + W  N  ++  D      V++   H L I
Sbjct: 13676 --------------KSVTFWCKV-NRLNVTLKWTKNGEEVPFDNRVSYRVDKY-KHMLTI 13719

Query: 453   TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
              +    D G     A    G+      L +IE       +FVE      V E +  V + 
Sbjct: 13720 KDCGFPDEGEYIVTA----GQDKSVAELLIIE----APTEFVEHLEDQTVTEFDDAVFSC 13771

Query: 513   RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             + +      + W ++G  I    + +   DG    L I   +  D   Y C  ++     
Sbjct: 13772 Q-LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVED----R 13826

Query: 573   ATRARLY 579
              +RARL+
Sbjct: 13827 KSRARLF 13833



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 2/79 (2%)

Query: 1858  EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
             EG+           P P   V W+ +GK +++  R    ND   A L++      D+G Y
Sbjct: 15327 EGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 15384

Query: 1918  TCKAINNLGQAVSSIRLNV 1936
             T    N LG A +SI + V
Sbjct: 15385 TITLENKLGSATASINVKV 15403



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/131 (23%), Positives = 52/131 (39%), Gaps = 5/131 (3%)

Query: 3657  LEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRF--TVEIKDNIDVPEGGPVH 3714
             LE +    F++   +   +       + +TI  E   PPR   +V +K  + V  G  V 
Sbjct: 20183 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-PPRIDLSVAMKSLLTVKAGTNVC 20241

Query: 3715  FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
              D  V   G P   + W  +G        +          L++  +  +D+G+YT  A N
Sbjct: 20242 LDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 20299

Query: 3775  KWGSATTTAKI 3785
               GS + T K+
Sbjct: 20300 SSGSKSATIKL 20310



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/84 (23%), Positives = 36/84 (42%)

Query: 4730  IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
             + V  G        +  K  PT+ W ++G L+      +M  + N   L + +   +D+G
Sbjct: 20232 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 20291

Query: 4790  TFTCRATTAAGQVETSAKLVVKSK 4813
              +T  A  ++G    + KL V  K
Sbjct: 20292 DYTITAENSSGSKSATIKLKVLDK 20315



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 17/71 (23%), Positives = 33/71 (46%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             +  + G P  ++    G P P++TW+ + + +     + I T    +TL +  +   D+ 
Sbjct: 29584 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 29643

Query: 560   WYQCTAQNVAG 570
              Y  T +N AG
Sbjct: 29644 RYFLTLENTAG 29654



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 16/179 (8%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  P   T++ KDI +  E     +E ++   G   +  +W  NG  I+++ + +     
Sbjct: 2965 TVTPIMITSMLKDI-NAEEKDTITFEVTVNYEG---ISYKWLKNGVEIKSTDKCQMRTKK 3020

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L I      D+  Y+  A      A + V+   ++        F  HI++I+ L+ 
Sbjct: 3021 LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIE--------FRKHIKDIKVLEK 3072

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             + A FEC V    +PD+ ++W  + Q ++ + RIK   +     L I  T+  D+G+Y
Sbjct: 3073 -KRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKY 3127



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/137 (21%), Positives = 59/137 (43%), Gaps = 10/137 (7%)

Query: 1270 IERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVH 1329
            ++ S+   ++ +E   E++  ++        ++ED  ++  P     L +  + EG  VH
Sbjct: 4253 LKPSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTP-----LVDTVSEEGDIVH 4307

Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED-SGVYTCQAT 1388
            L   +         V W+   K + +  +F+   + +   L +  V  ED  G Y C+A 
Sbjct: 4308 LTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 4363

Query: 1389 NQLGEAVTSCALRVIAK 1405
            N  G+  TS  L V+ +
Sbjct: 4364 NDSGKTATSAKLTVVKR 4380



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 7/140 (5%)

Query: 3662 PSHFKSGTESIQKLEETLH-KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVE 3720
            PS  K  + S    EE    K +E      K + P     + D +   EG  VH    + 
Sbjct: 4255 PSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVS-EEGDIVHLTTSIT 4313

Query: 3721 PVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD-AGEYTCRATNKWGSA 3779
               +    ++W+   +   +  +   L D     L ID +   D  GEY C A N  G  
Sbjct: 4314 NAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKT 4369

Query: 3780 TTTAKITCSAKRDIVLESQL 3799
             T+AK+T   +   V++ ++
Sbjct: 4370 ATSAKLTVVKRAAPVIKRKI 4389



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/69 (24%), Positives = 37/69 (53%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E ++ P+++ +W+  G+ + +  +  + S     +L+++     D G YTCKA N+ G  
Sbjct: 4405 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 4464

Query: 2996 FTSSTVYCT 3004
              ++T+  T
Sbjct: 4465 SCTATLTVT 4473



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/72 (29%), Positives = 32/72 (44%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            L I W+   K L  G    +T +    +L+L  V   DSG YTCK  N  G    S+ ++
Sbjct: 5162 LTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLF 5221

Query: 3003 CTSKDNLIERTQ 3014
                   +E+ +
Sbjct: 5222 VKEPATFVEKLE 5233



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 4/92 (4%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            P  FV +L  +  + +G      C+V     P ++I ++ N + ++ +++  ++F     
Sbjct: 5225 PATFVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVESTA 5282

Query: 2301 SLDIQHCVPEDAGEYSVKAINALG--HCTSAI 2330
             L +     ED+GEY  +A N  G  HC+S +
Sbjct: 5283 VLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIV 5314



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 2/98 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +T+ + P F + + +  ++ G     +  L+  G   + V W  +   I      R  +E
Sbjct: 5407 VTLREPPSFIKKIESTSSLRGGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTFE 5464

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +  +L L  +  +  G Y CQA N  G    S  L V
Sbjct: 5465 NNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV 5502



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            R+ P F + +++  +++ G TA F   L   G   + V W ++   I +   I  T +  
Sbjct: 5410 REPPSFIKKIESTSSLRGG-TAAFQATL--KGSLPITVTWLKDSDEITEDDNIRMTFENN 5466

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
              S+ +S +  + +G Y+C+A N  G
Sbjct: 5467 VASLYLSGIEVKHDGKYVCQAKNDAG 5492



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 3/98 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P FV+    P       N  ++ +    G   M ++WF + + +  G+    + D  
Sbjct: 5692 KEPPYFVE---KPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDT 5748

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
              +L++  A + D+G Y  +  N +G+A + A + V E
Sbjct: 5749 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE 5786



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 37/167 (22%), Positives = 68/167 (40%), Gaps = 18/167 (10%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            S+E +  + P F   L  +E ++  +    E  +T T  P  +V W  N + +++  ++ 
Sbjct: 5873 SIELKVKEPPTFIRELKPVEVVKYSD-VELECEVTGT--PPFEVTWLKNNREIRSSKKYT 5929

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530
                     L I+   P D+GEY C   N  G    +  + ++   + I      K +E 
Sbjct: 5930 LTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFI------KKIEN 5983

Query: 3531 TIDKIAALEGYSGTVDTLTPEAESGNPP-EFTTTPSDLILSENSSAH 3576
            T   + +   +  TV        +G+PP   T    D IL E+ + +
Sbjct: 5984 TTTVLKSSATFQSTV--------AGSPPISITWLKDDQILDEDDNVY 6022



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  ++  + K++ G S H E ++       +  +WF +GK++    +YR       V
Sbjct: 6163 PPSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSV 6219

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDS 3367
             L++     E++  Y C  +N  G D+
Sbjct: 6220 SLEVNNLELEDTANYTCKVSNVAGDDA 6246



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/88 (22%), Positives = 44/88 (50%), Gaps = 3/88 (3%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            + ++ PVF+     ++ ++  + +  +C L   G P  +V W+++++ +  S +      
Sbjct: 6439 IVKEPPVFSSFPPIVETLKNAEVS-LECELS--GTPPFEVVWYKDKRQLRSSKKYKIASK 6495

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
              + S+ I +V   D G Y C+A N +G
Sbjct: 6496 NFHTSIHILNVDTSDIGEYHCKAQNEVG 6523



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F K  +  EV  G  V   + +     P  +V W+   R + +G R    ++  
Sbjct: 6816 VQEPPSFVKEPEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDT 6873

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
               L++       +G Y C  +N  G+A  T+ + V
Sbjct: 6874 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 6909



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/105 (21%), Positives = 44/105 (41%), Gaps = 2/105 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  P  F+ ++  H+VE  + +  E          + + W ++G  + +  +   V    
Sbjct: 6909 VKEPAAFLKRLSDHSVEPGKSIILESTYTGTLP--ISVTWKKDGFNITTSEKCNIVTTEK 6966

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
               L+IL     D+G+Y C   N+ G D   A +S  + P  + +
Sbjct: 6967 TCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTE 7011



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K    F++ LS+   V  GK+I LE      G   + V W  +G ++T   +        
Sbjct: 6910 KEPAAFLKRLSDHS-VEPGKSIILESTYT--GTLPISVTWKKDGFNITTSEKCNIVTTEK 6966

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQA 1284
               L+I+++T  D G+Y+    N  G     A+V  +E    VT+ +  +A
Sbjct: 6967 TCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEA 7017



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 2/96 (2%)

Query: 1590 KEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGT 1649
            K+G+    E ++       +KV W+ N+  L    ++  +       L I     EDSG 
Sbjct: 7304 KQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGD 7361

Query: 1650 YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
            Y C A N +G+A  S    V +      +    GAL
Sbjct: 7362 YICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGAL 7397



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 2/101 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F     SV  + G  + F + I   G P  K++W K  + +             
Sbjct: 7757 VQEPPSFEQTPDSVEVLPGMSLTFTSVIR--GTPPFKVKWFKGSRELVPGESCNISLEDF 7814

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
               L++  +   +SG+Y+C   +  G A     L V   AT
Sbjct: 7815 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPAT 7855



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 2/103 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  P  F+ ++   +VE    +  E        P + + W ++  L+    R        
Sbjct: 7850 VKEPATFVKRLADFSVETGSPIVLEATYTGT--PPISVSWIKDEYLISQSERCSITMTEK 7907

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
               L+IL    ED  +Y C   N+ G+D  +A +S  + P  I
Sbjct: 7908 STILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFI 7950



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/98 (21%), Positives = 45/98 (45%), Gaps = 2/98 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + P     L++VE   G+ A  + ++    +  +++ WY  +  L+S   +         
Sbjct: 7945 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPE--IRISWYKEHTKLRSAPAYKMQFKNNVA 8002

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
            +L I      D G Y+C+A N++G   +S + ++  +K
Sbjct: 8003 SLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERK 8040



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 3/99 (3%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            V +E+   P F   L ++     G    FE R+  ++   L+V WY +G  LK  +  +T
Sbjct: 8035 VIKERKLPPFFARKLKDVHETL-GFPVAFECRINGSEP--LQVSWYKDGVLLKDDANLQT 8091

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASM 3510
                    L+I  T     G+Y C A N  G A ++A +
Sbjct: 8092 SFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F + L+++     G    F+CR+   G   L+V W+++  L++D + +  +      +
Sbjct: 8043 PFFARKLKDVHETL-GFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHNVAT 8099

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I        G Y C ASN LG
Sbjct: 8100 LQILQTDQSHIGQYNCSASNPLG 8122



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G  + FEC +  S +P L++ W+ +   L      +++   +  +L I  T +   G Y 
Sbjct: 8057 GFPVAFECRINGS-EP-LQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYN 8114

Query: 2848 CKATNSKGSATTSGSL 2863
            C A+N  G+A++S  L
Sbjct: 8115 CSASNPLGTASSSAKL 8130



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 4/104 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHN-GRSVTVGSRFKTYYDF 1232
            K+ P FV+ LS+   V  GK + L+  +E  G   + V WF + G  V         Y  
Sbjct: 8416 KAPPRFVKKLSDISTVV-GKEVQLQTTIE--GAEPISVVWFKDKGEIVRESDNIWISYSE 8472

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276
                L       A+ G+YT +  N  G     A + V+E + IV
Sbjct: 8473 NIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV 8516



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/94 (25%), Positives = 37/94 (39%), Gaps = 2/94 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   P  + +   ++  F    I        V WF     L+ G R     +     
Sbjct: 8701 PPSFVQKPDPMDVLTGTNVTFTS--IVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAE 8758

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            LE+  V    +G YTC  +N  G+A+ +  L +K
Sbjct: 8759 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 8792



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F + LS     +EG +  LE R+   G   + V W+ N   +   S  +  +    + 
Sbjct: 9176 PSFTKRLSETVEETEGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 9233

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSA-HTSAIV 1267
            L +  A   D G YT +  N  GSA  TS+IV
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIV 9265



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 4/76 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P +   +QDVT L EGQ+     +      P++K EWF NG+ L    R++T  +  +  
Sbjct: 9672 PAWERHLQDVT-LKEGQTCTMTCQF---SVPNVKSEWFRNGRILKPQGRHKTEVEHKVHK 9727

Query: 3342 LDILYCYEENSGEYEC 3357
            L I     E+ G+Y C
Sbjct: 9728 LTIADVRAEDQGQYTC 9743



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 3/73 (4%)

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EGQ     C+       N+K EWF+NG+ +    R +   +     L I D+ AED G Y
Sbjct: 9685 EGQTCTMTCQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQY 9741

Query: 1518 TCRAVNLVGTDEV 1530
            TC+  +L  + E+
Sbjct: 9742 TCKYEDLETSAEL 9754



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 18/78 (23%), Positives = 41/78 (52%), Gaps = 1/78 (1%)

Query: 265   PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
             P +I + P++     GAD  F  +L+ + +  V W +N   ++  +KH++++      L+
Sbjct: 13838 PVEIIRPPQDILEAPGADVVFLAELNKD-KVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQ 13896

Query: 325   VRNTQKSDSGHYTLLAEN 342
             + + +  D G Y  +A++
Sbjct: 13897 ICDIKPRDQGEYRFIAKD 13914



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 3/91 (3%)

Query: 2645  TTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
             T  L+++D +V EG+   L   V  R  P   + W K+G  +    RL    D     L 
Sbjct: 15315 TIDLETHDIIVIEGEK--LSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLE 15372

Query: 2704  INSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +      D+GIYT    N LG A ++ ++K+
Sbjct: 15373 VPKSVRADAGIYTITLENKLGSATASINVKV 15403



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 7/95 (7%)

Query: 491   PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK-------DGVPIIPNPELRIHTDG 543
             P  ++    + V EG  V + A+  G P P +TW K       +  P++ +  +      
Sbjct: 17044 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 17103

Query: 544   GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
                TL IP+++ SD   Y  TA N  G+ +   RL
Sbjct: 17104 DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 17138



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/84 (26%), Positives = 36/84 (42%)

Query: 4727  LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
             +  +VV  G   +F   I     PT +W  +G+ I     + +  +  ++VL I N    
Sbjct: 18444 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 18503

Query: 4787  DTGTFTCRATTAAGQVETSAKLVV 4810
             DTG +    + AAG    +  L V
Sbjct: 18504 DTGEYQITVSNAAGSKTVAVHLTV 18527



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 2/86 (2%)

Query: 3840  TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899
             TV   + +R   RV+ + +P   I W + GK+L    R   + D+  V L I      D 
Sbjct: 18846 TVRVGQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADH 18903

Query: 3900  GEYICRAVNDFGEDFTKATISCKKLP 3925
             G+YI  A N  G     A ++    P
Sbjct: 18904 GKYIISAKNSSGHAQGSAIVNVLDRP 18929



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 502   VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
             VR G P+ L A   G P P++TW+K G+  +   + ++      + L IP +   D+  Y
Sbjct: 19545 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVR-KGQVDLVDTMAFLVIPNSTRDDSGKY 19603

Query: 562   QCTAQNVAGSTA 573
               T  N AG  A
Sbjct: 19604 SLTLVNPAGEKA 19615



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 2/87 (2%)

Query: 776   LQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHL 835
             ++ L  ++ G N   +A  T    P   V W KDG  +  +  I         +L +  +
Sbjct: 20228 MKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSV 20285

Query: 836   RAEDAGSYTVRAVNKLGEAISTASIRV 862
               +D+G YT+ A N  G   +T  ++V
Sbjct: 20286 NRKDSGDYTITAENSSGSKSATIKLKV 20312



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/69 (30%), Positives = 34/69 (49%)

Query: 4525  VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
             V +G+  RL+  V G     + WL+  K+++   R +I   D    L++ +A   D G+Y
Sbjct: 24564 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 24623

Query: 4585  ECVAINSAG 4593
                A N AG
Sbjct: 24624 ILRASNVAG 24632



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 35/127 (27%), Positives = 50/127 (39%), Gaps = 8/127 (6%)

Query: 2629  VPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
             VP +  D  +Q  P       +Y  +  G+ + +E  V  R  PN  I W K+G  L   
Sbjct: 25228 VPVIAKDLTIQ--PSLKLPFNTYS-IQAGEDLKIEIPVIGRPRPN--ISWVKDGEPLKQT 25282

Query: 2689  ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPD 2748
              R+          L I     DD G YT  ATN  G A    S+ + ++    G  + P 
Sbjct: 25283 TRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKP---GPPVGPV 25339

Query: 2749  SLDRIGA 2755
               D + A
Sbjct: 25340 RFDEVSA 25346



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 2/98 (2%)

Query: 1977  KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
             +P    P     +  G  + +E  +  +  P   + W  +G P++Q  R           
Sbjct: 25238 QPSLKLPFNTYSIQAGEDLKIEIPV--IGRPRPNISWVKDGEPLKQTTRVNVEETATSTV 25295

Query: 2037  LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074
             L I     +D G Y   ATN+ G A    SV V  K G
Sbjct: 25296 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG 25333



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 5/98 (5%)

Query: 68    EPSPPIFE---QIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
             E  PPI E   + F       G + + +  ++G P P V+W +    + +  + +M   +
Sbjct: 28879 ENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK--RMNMEITD 28936

Query: 125   QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
               G  SL ++       G YT  A+N  G A   + ++
Sbjct: 28937 VLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 28974



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 6/113 (5%)

Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALD 3756
            FT E++D +   +     F+C      +P +++ W+ +G     G +    +D     L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ---LPQGMSGE 3806
            I  I   DA +Y+C         TT   I   A  + V E Q   +P+  SGE
Sbjct: 2233 ILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGE 2285



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 2776 FISHLNNIVCKEGDNIH-FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            F   L ++V KE D +  FEC      +P +K++W+ +   +  G +Y+   D     L 
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2232

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTS 2860
            I      D+  Y+C     +   TT+
Sbjct: 2233 ILTIDTSDAEDYSCVLVEDENVKTTA 2258



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P    PL    + EG  +H  T I    +    + W    + + +  +F  +      +L
Sbjct: 4289 PMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTL 4344

Query: 697  DMLSLNIQD-SGEYTCRAVSATGVAETKAVLHVTPRA 732
             +  +N +D  GEY C A++ +G   T A L V  RA
Sbjct: 4345 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 4381



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 1/116 (0%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF-EARVEPQSDLTMTVEW 1079
            +Y+ +A   S +T    K+T   R    +K   + +E    H  +   E QS   +  +W
Sbjct: 4357 EYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQW 4416

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +  G++I  +++          +L+I   +  D G YT  A N  G    +A++TV
Sbjct: 4417 FKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4472



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/72 (27%), Positives = 35/72 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P ++  W K+G  L+     K +       L +++L   D G+Y+CKA+N  G  +  A 
Sbjct: 4505 PVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAE 4564

Query: 2732 IKIEDRHWLLGE 2743
            + I D+   + E
Sbjct: 4565 LIIIDKPHFIKE 4576



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/93 (23%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
            S E    + P FI+ L+   ++  G NA  + +++        + W+KD + I +S +  
Sbjct: 4749 STEIVIKEPPSFIKTLEP-ADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYR 4805

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
                   V L I    + D G Y     N++G+
Sbjct: 4806 LFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 4838



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 3/99 (3%)

Query: 1705 EVITQAPVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            E+I + P   +   + I+V     A  E  +   G P+L+ +W ++G P+ AS +     
Sbjct: 4937 ELIVKEPAKIIERAELIQVTAGDPATLEYTV--AGTPELKPKWYKDGRPLVASKKYRISF 4994

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
                  L        DSG YT    NE+G +   +T  V
Sbjct: 4995 KNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTV 5033



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/67 (26%), Positives = 32/67 (47%)

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
            P ++ +WY +G+ L +  +YR S     A L   +    DSG+YT +  N +G +     
Sbjct: 4971 PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 5030

Query: 1934 LNVQSKE 1940
              V  ++
Sbjct: 5031 FTVLDRD 5037



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 3/154 (1%)

Query: 1801 FVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQ 1860
            FV+  ASL++     +          +S   +     + V + P F+T+  G   +  G 
Sbjct: 5090 FVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTK-PGSKDVLPGS 5148

Query: 1861 SAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920
            +   +   +      + + W+   K L SG     + +   ++L++  V   DSG YTCK
Sbjct: 5149 AVCLKSTFQG--STPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCK 5206

Query: 1921 AINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
              N  G    S  L V+   + +   +    L+K
Sbjct: 5207 VSNVAGGVECSANLFVKEPATFVEKLEPSQLLKK 5240



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 2/86 (2%)

Query: 1446 FVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALD 1505
            FV + +  + + +G      CK+       +K+ WF N + +    + R         L 
Sbjct: 5228 FVEKLEPSQLLKKGDATQLACKVTGTPP--IKITWFANDREIKESSKHRMSFVESTAVLR 5285

Query: 1506 IIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            + D+  EDSG Y C A N  G+D  S
Sbjct: 5286 LTDVGIEDSGEYMCEAQNEAGSDHCS 5311



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 2/87 (2%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            + P  +T      ++ +GD A  + +     +  +T  WF +GQ++  G +Y+ +     
Sbjct: 5503 KEPATITEEAVSIDVTQGDPATLQVKFSGTKE--ITAKWFKDGQELTLGSKYKISVTDTV 5560

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEA 2193
              L I+ T  +DSG Y  +  N +G +
Sbjct: 5561 SILKIISTEKKDSGEYTFEVQNDVGRS 5587



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 3/107 (2%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            I PP F  +L+    + +G     EC V   H   + I+++ + + + ++ ++  +F   
Sbjct: 5599 IIPPSFTKKLKKMDSI-KGSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDN 5655

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQ 2345
               L+I      D+G Y+  A N  GH   +  +TV      + + Q
Sbjct: 5656 TAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 5702



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F+V      A+    + F+  ++  G P  KI+W K+   + +  +        
Sbjct: 6253 VKEPPSFLVKPGRQQAIPDSTVEFKAILK--GTPPFKIKWFKDDVELVSGPKCFIGLEGS 6310

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
               L++ S++   +G+YTC   +  G      +L VT
Sbjct: 6311 TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVT 6347



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 19/65 (29%), Positives = 32/65 (49%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI+WFK+ V L +G +     +     L++ S+    +G YTC  TN +G    T  
Sbjct: 6284 PPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTM 6343

Query: 2732 IKIED 2736
            + + +
Sbjct: 6344 LLVTE 6348



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            PVF+     +E L+  E    E  L+ T  P  +V WY + + L++  +++         
Sbjct: 6444 PVFSSFPPIVETLKNAE-VSLECELSGT--PPFEVVWYKDKRQLRSSKKYKIASKNFHTS 6500

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            + I      D GEY C+A N  G      ++K++
Sbjct: 6501 IHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLK 6534



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            +++P F     S D ++ G+    E  V     P ++I W K+   +  G     T    
Sbjct: 7195 KKSPFFDIKPVSID-VIAGESADFECHVTG-AQP-MRITWSKDNKEIRPGGNYTITCVGN 7251

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               L I  +   DSG YTC+ATN +G+ + +A + +++
Sbjct: 7252 TPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE 7289



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 4/95 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK-TINDFGFV 3615
            PP F  TP  + +    S  F    +       +V+WF   + L+ G     ++ DF   
Sbjct: 7760 PPSFEQTPDSVEVLPGMSLTFTS--VIRGTPPFKVKWFKGSRELVPGESCNISLEDF-VT 7816

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             LE+  V   ++G Y+C  TN  G A+ +  L VK
Sbjct: 7817 ELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 7851



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 3/98 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F       D L  G +V   + V  +  P   + WFK    L  G R   + + 
Sbjct: 8698 VREPPSFVQKPDPMDVLT-GTNVTFTSIV--KGTPPFSVSWFKGSSELVPGDRCNVSLED 8754

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             +  L +  +    SG YTC  +N  G+A  T  + I+
Sbjct: 8755 SVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 8792



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 2/105 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            +  P KF+ ++  +++E+ + +  E        P + + W +NG  +    R        
Sbjct: 8791 IKAPAKFVKRLNDYSIEKGKPLILEGTFTGT--PPISVTWKKNGINVTPSQRCNITTTEK 8848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
               L+I     ED+G+Y C   N  G+D   A I   + P  + Q
Sbjct: 8849 SAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQ 8893



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 7/97 (7%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            +K+ W  + + +  G +++++       L ++ V + DSG YTC A N+ G+        
Sbjct: 9109 IKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKD------S 9162

Query: 3003 CTSKDNLIERTQHPKGTEGL-EKIQNLEDSLRKEPGQ 3038
            CT++ N+ ER   P  T+ L E ++  E +  K  G+
Sbjct: 9163 CTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGR 9199



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 5/86 (5%)

Query: 3826  VSTPP-KFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
             V  PP +F   ++  TVEE      EC V  +E+ K  ++W++NG  +    +Y  V D 
Sbjct: 13207 VKEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAK--VKWFKNGTEILKSKKYEIVADG 13263

Query: 3885  GFVSLDILYVYAEDSGEYICRAVNDF 3910
                 L I     ED   Y C A  DF
Sbjct: 13264 RVRKLVIHDCTPEDIKTYTCDA-KDF 13288



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 60/258 (23%), Positives = 104/258 (40%), Gaps = 31/258 (12%)

Query: 89    AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCT 147
             A+FE +L       V W +  A + +  KY +      G V +L I +    DE EY+C 
Sbjct: 13318 ARFECEL-SRENAKVKWFKDGAEIKKGKKYDII---SKGAVRILVINKCLLDDEAEYSCE 13373

Query: 148   ARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKV 207
              R      + +V ++ E                 VSET       T     E S+   +V
Sbjct: 13374 VRTARTSGMLTV-LEEEAVFTKNLANI------EVSET------DTIKLVCEVSKPGAEV 13420

Query: 208   AYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEI--DRSLGPVSP 265
              +  G      D+  ++T  Y +L E   R  + +    E     +  +   R+ G V  
Sbjct: 13421 IWYKG------DEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKV 13474

Query: 266   PKIA----QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
              ++A     KP+N ++ EG  A+F   +S    P V W ++ + L + +K+++I      
Sbjct: 13475 HELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR 13533

Query: 322   TLRVRNTQKSDSGHYTLL 339
              L V++    D G Y ++
Sbjct: 13534 VLVVKDATLQDMGTYVVM 13551



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 2776  FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
             F+ HL +    E D+  F C +  SR+    ++W+ N + +  G +YK   D S   L I
Sbjct: 13752 FVEHLEDQTVTEFDDAVFSCQL--SREKA-NVKWYRNGREIKEGKKYKFEKDGSIHRLII 13808

Query: 2836  THTYEEDSGIYTCKATNSKGSA 2857
                  +D   Y C   + K  A
Sbjct: 13809 KDCRLDDECEYACGVEDRKSRA 13830



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 10/101 (9%)

Query: 2947  WYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
             W F  KVLE G R K+ +   +  L +      D GIYT K  N+        T+     
Sbjct: 14355 WCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR------VKTISGEID 14408

Query: 3007  DNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRP 3047
              N+I R   PK  +    I      L  EP   PDDD G P
Sbjct: 14409 VNVIARPSAPKELK-FGDITKDSVHLTWEP---PDDDGGSP 14445



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 2781  NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
             ++I+  EG+ +           PT  + W  + K + +  R    +D     L++  +  
Sbjct: 15321 HDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVR 15378

Query: 2841  EDSGIYTCKATNSKGSATTSGSLRCTG 2867
              D+GIYT    N  GSAT S +++  G
Sbjct: 15379 ADAGIYTITLENKLGSATASINVKVIG 15405



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 4613  KPQTKAANAPPEIIE---PLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
             +P T A    P  +E    +K  I +  G+ +     + G+P+PT  W K +  +   + 
Sbjct: 16018 QPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRV 16077

Query: 4669  FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
               +     +  L I +A  +D G Y   A NS G    AA+++V
Sbjct: 16078 V-IDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 16120



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/72 (25%), Positives = 30/72 (41%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             RF     G P+P  KW  +   IK    + + T +  S+L I+     D+  +     N 
Sbjct: 18456 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA 18515

Query: 4489  GGTAKCSANLVV 4500
              G+   + +L V
Sbjct: 18516 AGSKTVAVHLTV 18527



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 263   VSPPKIAQKPRNSKL---QEGADAQFQVQLSGNPRPRVTWFKNG-QRLINSNKHEIITTH 318
             + PP+I       KL   + G   +    + G P P+VTW K G   ++   + +++ T 
Sbjct: 19528 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTM 19587

Query: 319   NHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L + N+ + DSG Y+L   NP G
Sbjct: 19588 --AFLVIPNSTRDDSGKYSLTLVNPAG 19612



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 69/327 (21%), Positives = 120/327 (36%), Gaps = 22/327 (6%)

Query: 2933  GQVEPKNDPDLKIEWYFNGKVLEQGSRF-KLTSDFGFVTLDLVDVYERDSGIYTCKAYNK 2991
             G  EP   P +  ++ F      + +R  K+  D  FV  D  D    D G        +
Sbjct: 20000 GISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPD---SDGGSPIIGYLIE 20056

Query: 2992  RGEAFTSSTVYCTSKDNLIERTQHPKG--TEGLE---KIQNLEDSLRKEPGQQPDDDTGR 3046
             R E   +S ++  + D L+  T++P     EGLE   +I  L  +    P +  +  T R
Sbjct: 20057 RKER--NSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR 20114

Query: 3047  PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
              P       +++D+++  ++   A     G  S +I +F     +     +R   A   +
Sbjct: 20115 MPVDPPGKPEVIDVTKSTVSLIWARPKHDGG-SKIIGYFVEACKLPGDKWVRCNTAPHQI 20173

Query: 3107  VLE-ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK----SKGQKPRFTTHI--QNIE 3159
               E    T   +   Y  RA  +     IS   E  D     ++   PR    +  +++ 
Sbjct: 20174 PQEEYTATGLEEKAQYQFRAIARTA-VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 20232

Query: 3160  GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
              +K G +   + TV     P   + W  +G  ++ +  IK         L++      DS
Sbjct: 20233 TVKAGTNVCLDATVF--GKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 20290

Query: 3220  GEYVCRAYNKYGEDFTRATINCYGKGG 3246
             G+Y   A N  G       +    K G
Sbjct: 20291 GDYTITAENSSGSKSATIKLKVLDKPG 20317



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 4/103 (3%)

Query: 904   ESTQKPEFKTPIK--DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
             +  + P+ K  +K  D + +K G     EA +   G     +EW KDG+ +E ++++   
Sbjct: 22381 DDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS--GRPPPTMEWSKDGKELEGTAKLEIK 22438

Query: 962   FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                    L  K  T  D+G YT  A N  G A    N+ ++ +
Sbjct: 22439 IADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 22481



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/106 (21%), Positives = 47/106 (44%), Gaps = 4/106 (3%)

Query: 380   EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
             ++ +E+   ++ P+F        V  G+  R +  V G+P P + W   D++I +    +
Sbjct: 24544 KDEVELPRISMDPKFRDTIV---VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCE 24600

Query: 440   ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             I  N      L++ +    D G     A N +G  +F   + V+++
Sbjct: 24601 I-KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR 24645



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/105 (23%), Positives = 39/105 (37%), Gaps = 4/105 (3%)

Query: 902   VPESTQKPEFKTPIK--DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT 959
             V +  + P     +K  D I +K G      A +   G     + W KDG  +E  +R  
Sbjct: 26707 VKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIA--GRPLPVISWAKDGIEIEERARTE 26764

Query: 960   TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                   +  LT+K     D G Y     N  G  + + N  ++ K
Sbjct: 26765 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 26809



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 2/92 (2%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             EF     D + IK G     +A ++  G    RV W KDG  +E    +      G  +L
Sbjct: 28886 EFGPEYFDGLIIKSGESLRIKALVQ--GRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSL 28943

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              ++  T    G YT  A NA G A     + +
Sbjct: 28944 FVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 28975



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/79 (25%), Positives = 40/79 (50%)

Query: 4525  VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
             + SG+ +R+   V G     V W K+G +++  +  +I +  G+ +L + +A     G Y
Sbjct: 28897 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28956

Query: 4585  ECVAINSAGEARCDAECVV 4603
                A N++G A+ + +  V
Sbjct: 28957 TVEAKNASGSAKAEIKVKV 28975



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 502   VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
             VR G  + L     G PTP   W K    +    +  IHT    STL +     +DA  Y
Sbjct: 29296 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD--IHTTDSFSTLTVENCNRNDAGKY 29353

Query: 562   QCTAQNVAGS 571
               T +N +GS
Sbjct: 29354 TLTVENNSGS 29363



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 11/147 (7%)

Query: 3670 ESIQKLEETLHKREEITIEDEKPN-----PPRFTVEIKDNID---VPEGGPVHFDCRVEP 3721
            E  ++ ++ L +  +ITI   KP+     P     +I + I    V +G   HF  RV  
Sbjct: 2044 ELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRV 2101

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
            VG P    +W+ NG       R++    +     L I  + A D+     +A N  G  +
Sbjct: 2102 VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETS 2161

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEK 3807
            + A +   AK+ I    +L   ++ EK
Sbjct: 2162 SHAFLLVQAKQLITFTQELQDVVAKEK 2188



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F K  +D  V E K   F+C V+  P   V W  +D++++     KI   E   H L+I
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQ-KEKYVHRLLI 3116

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAF----QCRLNVIEKEQVVAPK 492
             +  +SD+G  T VA  N S    F      R+  I+KE  V  K
Sbjct: 3117 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 3161



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 5/122 (4%)

Query: 1707 ITQA--PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            +T+A  P F    K +     +AA F   +   G P +   W ++G  +  S        
Sbjct: 4472 VTEAYPPTFLSRPKSLTTFVGKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWKISDA 4529

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH-ESALQKIQQ 1823
                 L +  +  +D G Y+C+A N+ G  +  + L +  K     E +  +SA+ K   
Sbjct: 4530 ENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVH 4589

Query: 1824 LE 1825
            LE
Sbjct: 4590 LE 4591



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/74 (28%), Positives = 30/74 (40%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   +   W KDG  +  S             L + ++T+ D G Y+C+A N  G     
Sbjct: 4503 GTPVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQ 4562

Query: 997  ANLTIVTKKDIIAE 1010
            A L I+ K   I E
Sbjct: 4563 AELIIIDKPHFIKE 4576



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 7/109 (6%)

Query: 2218 EKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIE 2277
            E +  + +   ST I ++EP    P F+  L     +  G  A  +C+V         I 
Sbjct: 4738 EAVNDVGSDSCSTEIVIKEP----PSFIKTLE-PADIVRGTNALLQCEVSGTGP--FEIS 4790

Query: 2278 FYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHC 2326
            ++ + K ++S+ ++ +      V L+I      D GEY     N +G C
Sbjct: 4791 WFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKC 4839



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            +++ P F   L+  D +V G +  L+ +V   T P  +I WFK+   + +  + +     
Sbjct: 4754 IKEPPSFIKTLEPAD-IVRGTNALLQCEVSG-TGP-FEISWFKDKKQIRSSKKYRLFSQK 4810

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGE 2725
             LV L I S  + D G Y C   N +G+
Sbjct: 4811 SLVCLEIFSFNSADVGEYECVVANEVGK 4838



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 3410 TSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRF 3469
            TSV E   K P   +  + +  +  G+ A  E  +  T  P LK +WY +G+ L A  ++
Sbjct: 4933 TSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGT--PELKPKWYKDGRPLVASKKY 4990

Query: 3470 RTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEA 3504
            R         L+       DSG+Y     N  G +
Sbjct: 4991 RISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSS 5025



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 3/114 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F     + +V  G  V L++T       T+R  W+   + +  G     T +  
Sbjct: 5129 VQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIR--WFKGNKELVSGGSCYITKEAL 5186

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKK 2087
              +L++      D+GTY CK +N  G    ++++ V  +   +++ L+  +L K
Sbjct: 5187 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV-KEPATFVEKLEPSQLLK 5239



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F VE   + DV     V     V   G   M I WF + +   +G+      D    
Sbjct: 5694 PPYF-VEKPQSQDVNPNTRVQLKALVG--GTAPMTIKWFKDNKELHSGAARSVWKDDTST 5750

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +L++    A D+G Y C+ +N  G+AT+ A +
Sbjct: 5751 SLELFAAKATDSGTYICQLSNDVGTATSKATL 5782



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 8/119 (6%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            +P  I+  A    + E   + LE  V     P+LK++W  +GK +     F ++ +    
Sbjct: 6066 EPAQIVEKAKSVDVTEKDPMTLECVVA--GTPELKVKWLKDGKQIVPSRYFSMSFENNVA 6123

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNL 3028
            +  +  V ++DSG YT K  N     F SS+  C +   ++++   P  T+ L K+  +
Sbjct: 6124 SFRIQSVMKQDSGQYTFKVEND----FGSSS--CDAYLRVLDQNIPPSFTKKLTKMDKV 6176



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/106 (18%), Positives = 47/106 (44%), Gaps = 3/106 (2%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            +D+  PP F  ++     ++   +   EC+++  G   +  +WF +GK +    ++  + 
Sbjct: 6158 LDQNIPPSFTKKLTKMDKVLG-SSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVC 6214

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                V++    +  ED+  Y C+ +N+ G D    ++     P  +
Sbjct: 6215 HERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFL 6260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 4/119 (3%)

Query: 3253 QPDSLAK-IRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDD 3311
            +P +  K I ++++  G ++   +    EP   + +   +T  V G++   E ++     
Sbjct: 6601 EPANAGKYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTV-GETCTLECKVAGT-- 6657

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
            P+L VEW+ +GK L    +++      I  L IL    +++G Y     N +G+ S  A
Sbjct: 6658 PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTA 6716



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 1982 KPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILY 2041
            KP+ + +V  G     E  +T      MR+ W  + + ++ G  +  T       L IL 
Sbjct: 7203 KPV-SIDVIAGESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILK 7259

Query: 2042 AYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                D+G Y C+ATN VG+ + ++ + V
Sbjct: 7260 VGKGDSGQYTCQATNDVGKDMCSAQLSV 7287



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 4/108 (3%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN-GKPIKTGHRFRPAYEFDY 1367
            + P+F + L +  T+ G  V L   ++  G Q + V W  + G+ I+     R ++  + 
Sbjct: 7476 EPPRFVKKLSDTSTLIGDAVELRAIVE--GFQPISVVWLKDRGEVIRESENTRISFIDNI 7533

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              L L S    +SG Y CQ  N  G    S  L V+ +   I+E   P
Sbjct: 7534 ATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL-EPARIIEKPEP 7580



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 6/114 (5%)

Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297
            +I PP F+ +L+    +  G +   EC+V       + + ++ +G  + S  +   +F  
Sbjct: 7664 RIVPPSFIRKLKDVNAIL-GASVVLECRVSG--SAPISVGWFQDGNEIVSGPKCQSSFSE 7720

Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
               +L++    P D G Y+  A N  G    +  +TV    S     Q P+ +E
Sbjct: 7721 NVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSF---EQTPDSVE 7771



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 2/112 (1%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P     LK+V    G     E R+     A + V W+ +   + SG +   + +     L
Sbjct: 7668 PSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 7725

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN 1689
            ++    P D+G YTC A N  G    S +  V    S          LP ++
Sbjct: 7726 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMS 7777



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +K+     G  V LE  ++      + V W+ +G  +  G + ++++      L
Sbjct: 7668 PSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 7725

Query: 2038 DILYAYAEDTGTYMCKATNAVG 2059
            ++      DTG Y C A N  G
Sbjct: 7726 NLSLLEPSDTGIYTCVAANVAG 7747



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/90 (24%), Positives = 37/90 (41%), Gaps = 2/90 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + PI       +E  +G   H E  L         V WY + + L+SG ++   +     
Sbjct: 8324 EPPIFRKKPHPIETLKGADVHLECEL--QGTPPFHVSWYKDKRELRSGKKYKIMSENFLT 8381

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSG 1665
            ++ I++    D G Y C+A N +G     G
Sbjct: 8382 SIHILNVDAADIGEYQCKATNDVGSDTCVG 8411



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 4/111 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P FV +P  ++ V+ G +V F   ++        V WFK    +  G R     +     
Sbjct: 8702 PSFVQKPDPMD-VLTGTNVTFTSIVKGTPP--FSVSWFKGSSELVPGDRCNVSLEDSVAE 8758

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQ 1554
            L++ D+    SG YTC   N  G    +  L  ++    V+   N+  +E+
Sbjct: 8759 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRL-NDYSIEK 8808



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 18/69 (26%), Positives = 31/69 (44%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W +    +   +R     +     L +  V+   SG YTC   NE G+A  +
Sbjct: 8727 GTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCT 8786

Query: 1798 STLFVQSKA 1806
            + L++++ A
Sbjct: 8787 THLYIKAPA 8795



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/106 (24%), Positives = 53/106 (50%), Gaps = 6/106 (5%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S R+ + E K +PP F   L     V  G++A FEC V       +++ +  + + ++S 
Sbjct: 9068 SARLILTEGK-NPPFFDIRLAPVDAVV-GESADFECHVTGTQP--IKVSWAKDSREIRSG 9123

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALG--HCTSAISM 2332
             ++ I++      L +      D+G+Y+  A+N +G   CT+ +++
Sbjct: 9124 GKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI 9169



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 2/105 (1%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   L+      EG+    E RV   + P +T+ W+ N  +I+       T     + 
Sbjct: 9176 PSFTKRLSETVEETEGNSFKLEGRVAG-SQP-ITVAWYKNNIEIQPTSNCEITFKNNTLV 9233

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQH 2213
            L +      D+G Y CK +N  G A+ T ++ +   +   +  QH
Sbjct: 9234 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH 9278



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 18/41 (43%), Positives = 25/41 (60%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK 3148
            LEI  T  TDSG Y C A N+ G+ E +V L+  ++ K +K
Sbjct: 9439 LEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEK 9479



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            L+EG       Q S  P  +  WF+NG+ L    +H+    H    L + + +  D G Y
Sbjct: 9683 LKEGQTCTMTCQFSV-PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQY 9741

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
            T   E+    + TS  L +E+    +   +R Q I  ++ +      E+S
Sbjct: 9742 TCKYED----LETSAELRIEAEPIQFT--KRIQNIVVSEHQSATFECEVS 9785



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 4/72 (5%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            FT+ +QNI  + E Q+A F+C    V      V W++    + +S +    +D     MT
Sbjct: 9763 FTKRIQNIV-VSEHQSATFECE---VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMT 9818

Query: 2438 ISHVRDEDEGVY 2449
            I +V  +DEGVY
Sbjct: 9819 IHNVTPDDEGVY 9830



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 3557  PPEFTTTPSDLILSEN----SSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
             P +F     D+IL+E+    SSA FEC + P   S+    W  +G  +    + + I D 
Sbjct: 12041 PLKFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADG 12097

Query: 3613  GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
                 L I  V   DAG YTC     + E T + KL V+
Sbjct: 12098 KDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 12135



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 85/408 (20%), Positives = 153/408 (37%), Gaps = 38/408 (9%)

Query: 1800  LFVQSKASLQLESQHESALQKIQQLEDSSRYQ-----RREDVEVAVNQA-PRFITQLNGP 1853
             L      S+Q E +  S   K   ++D+S+ +        + ++ V +  P F  +L   
Sbjct: 12895 LHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDY 12954

Query: 1854  TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
             T + E      +C I     P   V+W+ +GK ++         D     L +      D
Sbjct: 12955 TGV-EKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSD 13010

Query: 1914  SGEYTCKAINNLGQAVSSIRLNVQSKE-SIIRDSQHESALEKIQYLEDDS-RYKRAVQDD 1971
              G+YTC    + G   +S +L+++ +E  ++R       L  ++ +E ++ R++  + +D
Sbjct: 13011 IGQYTC----DCGTDKTSGKLDIEDREIKLVRP------LHSVEVMETETARFETEISED 13060

Query: 1972  SFVVEKPQFGKPI---KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
                      G+ +    + E+ E   +H         D T  V++           R K 
Sbjct: 13061 DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKP 13120

Query: 2029  TYDFGYVALDILYAYAEDTGTYMCKATNA--------VGEAVTTSSVKVDAKSG-LYLDT 2079
                     L  +   A +T T+ C+ +           G+ +  S   V    G ++  T
Sbjct: 13121 RVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLT 13180

Query: 2080  LDEQRLKKIQELEKYERP-KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPIND 2138
             L + +L+   E++   +  K        + PV  T     + ++EG  A  EC V   N 
Sbjct: 13181 LRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSREN- 13239

Query: 2139  PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186
                 + WF NG +I    +Y    D     L I     ED  TY C A
Sbjct: 13240 --AKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 13285



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 1/87 (1%)

Query: 4511  IVPPSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
             + PP+  L  ++ + +  G+   L  + +G     V W K+   V  D R  I     T 
Sbjct: 17742 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 17801

Query: 4570  TLLILEAYPQDSGKYECVAINSAGEAR 4596
              L  ++A   DSGKY  V  NS G  +
Sbjct: 17802 ALEKIKAKRSDSGKYCVVVENSTGSRK 17828



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT-FFNFGYVA 968
             E    + + + +K G    F A +  +   T +  W  DG  ++     T    NF  V 
Sbjct: 18438 ELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEHYTVETDNFSSV- 18494

Query: 969   LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             LTIK+    D G Y     NA G  T + +LT++
Sbjct: 18495 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVL 18528



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 381   ERIEISEKALAPQF-VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD-DYNH 438
             E + + E    P   +K+     V  G   R +  V G+P+PEV W   D+   D   + 
Sbjct: 19117 EEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAW-TKDKDATDLTRSP 19175

Query: 439   KILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             ++ ++  + +    +T    SD G     A N +G       +NV++K
Sbjct: 19176 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDK 19223



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 4511  IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             ++PP   +  Q + + +G+ +R++  V G       W K   +V       + + D +  
Sbjct: 19824 LLPPKILMPEQ-ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 19882

Query: 4571  LLILEAYPQDSGKYECVAINSAG 4593
             L+I +   +DSG Y   A NS+G
Sbjct: 19883 LIIKDVTRKDSGYYSLTAENSSG 19905



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/66 (28%), Positives = 33/66 (50%)

Query: 1874  PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             P   V W  +G +L+     + +       L++ +V  +DSG+YT  A N+ G   ++I+
Sbjct: 20250 PMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 20309

Query: 1934  LNVQSK 1939
             L V  K
Sbjct: 20310 LKVLDK 20315



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 2/81 (2%)

Query: 85    QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
             +  N + +  ++G P P VSW + + PL    + S+       + +L++      D G+Y
Sbjct: 20923 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV--ESSAVNTTLIVYDCQKSDAGKY 20980

Query: 145   TCTARNQYGEAICSVYIQPEG 165
             T T +N  G    ++ I+  G
Sbjct: 20981 TITLKNVAGTKEGTISIKVVG 21001



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 1/88 (1%)

Query: 915   IKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSV 974
             IKD ++IK G      A +  +G    +  W K G+ +  S             LTIK  
Sbjct: 21311 IKDGLTIKAGDTIVLNA-ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYA 21369

Query: 975   TVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             T  DAG YT  A N  G       +T++
Sbjct: 21370 TRKDAGEYTITATNPFGTKVEHVKVTVL 21397



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%)

Query: 4508  RGGIVPPSFTLTAQ---NVNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKIL 4563
             R  + PP  ++  +    + V +G+  ++D  + G KPI  + W+K  +++    R +I 
Sbjct: 23462 RDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG-KPIPTIQWIKGDQELSNTARLEIK 23520

Query: 4564  EEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
               D   +L + +A   DSG Y   A N AGE
Sbjct: 23521 STDFATSLSVKDAVRVDSGNYILKAKNVAGE 23551



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/72 (31%), Positives = 33/72 (45%)

Query: 499   TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             T+ V  GE   ++A   G P P I W K    +     L I +   A++L +  A   D+
Sbjct: 23479 TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 23538

Query: 559   AWYQCTAQNVAG 570
               Y   A+NVAG
Sbjct: 23539 GNYILKAKNVAG 23550



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQKPR---NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             V  P+I+  P+      +  G   + +  + G P P + W +  + +  S + EI  T  
Sbjct: 24547 VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 24606

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
                L V++  + D G Y L A N  G
Sbjct: 24607 KALLIVKDAIRIDGGQYILRASNVAG 24632



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 2/56 (3%)

Query: 2404  GDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             G P   +EW R +K IE+S+R   K  DF  + +    +R  D G Y+ RASN+ G
Sbjct: 24578 GKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIR-IDGGQYILRASNVAG 24632



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/68 (32%), Positives = 28/68 (41%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             + VR G  V L     G P P I+W KDG+P+  +  +R        TL I  AK     
Sbjct: 28500 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 28559

Query: 560   WYQCTAQN 567
              Y     N
Sbjct: 28560 KYTVILDN 28567



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 1055  IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
             I  G+S   +A V+ +      V W+ +G +I     ++     G  +L +     +  G
Sbjct: 28897 IKSGESLRIKALVQGRP--VPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28954

Query: 1115  VYTVVARNAAGEAQLSASMTVE 1136
             VYTV A+NA+G A+    + V+
Sbjct: 28955 VYTVEAKNASGSAKAEIKVKVQ 28976



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I  L ++ C E  N+ FE  +  S    + + W F +K +   ++YK         L + 
Sbjct: 2536 IRGLRDLTCTETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVL 2592

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            +  ++D G YT  A    G   TSG L   G
Sbjct: 2593 NMMKDDEGKYTFYA----GENITSGKLTVAG 2619



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 5/98 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P+   P+ D    E    H    +    +    V W      + +  +   + D     L
Sbjct: 4289 PMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTL 4344

Query: 1771 NMKYVNPED-SGTYTCRAINELGEAVTSSTLFVQSKAS 1807
             +  VN ED  G Y C A+N+ G+  TS+ L V  +A+
Sbjct: 4345 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 4382



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA-MNFGWVYPEDSGEYLCRA 4050
            KF C++     PN++ +WF  G+ +   ++ + I    Y++ +        D GEY C+A
Sbjct: 4401 KFTCEIQSA--PNVRFQWFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEYTCKA 4457

Query: 4051 TNLYGMDETKAVIKTT 4066
            +N YG     A +  T
Sbjct: 4458 SNEYGSVSCTATLTVT 4473



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 3/91 (3%)

Query: 2369 EPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428
            E V ++ P F + L+  D I  G  A   C +   G    ++ WF+++K I  S +    
Sbjct: 4751 EIVIKEPPSFIKTLEPAD-IVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLF 4807

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                 V + I      D G Y C  +N +G+
Sbjct: 4808 SQKSLVCLEIFSFNSADVGEYECVVANEVGK 4838



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 18/51 (35%), Positives = 24/51 (47%)

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            L + W+  NK L SG     T      +L++      DSGTYTC+  N  G
Sbjct: 5162 LTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAG 5212



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/106 (22%), Positives = 46/106 (43%), Gaps = 2/106 (1%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++   F   L+    L +G    L  +V     P +KI WF N   +   ++ + +F  
Sbjct: 5222 VKEPATFVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVE 5279

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                L +  +  +DSG Y C+A N  G    ++ + +++  +   E
Sbjct: 5280 STAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKE 5325



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 2/96 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F+   +S       ++  +  +   G   M I+W K+ + + + +  +      
Sbjct: 5691 VKEPPYFVEKPQSQDVNPNTRVQLKALVG--GTAPMTIKWFKDNKELHSGAARSVWKDDT 5748

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
              SL++ +    DSG Y C+  +  G A +KA L V
Sbjct: 5749 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFV 5784



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 17/62 (27%), Positives = 33/62 (53%)

Query: 3452 LKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMK 3511
            + ++W+ + K L +G+    + D     LE+      DSG Y+C+  N+ G A + A++ 
Sbjct: 5724 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 5783

Query: 3512 VQ 3513
            V+
Sbjct: 5784 VK 5785



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 37/183 (20%), Positives = 74/183 (40%), Gaps = 10/183 (5%)

Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314
            DS   I E ++  G+   +      EPP F +    + + ++      E  L     P  
Sbjct: 6417 DSGDFICEAQNPAGSTSCSTKVIVKEPPVF-SSFPPIVETLKNAEVSLECELSGT--PPF 6473

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKC 3374
            +V W+ + ++L    +Y+         + IL     + GEY C A N++G D+    +K 
Sbjct: 6474 EVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL 6533

Query: 3375 ------TSKEN-LILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLS 3427
                   SK N L + +  P  ++  +E  Q +    ++ K+  + E +     F   ++
Sbjct: 6534 KEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVA 6593

Query: 3428 NIE 3430
             ++
Sbjct: 6594 TLQ 6596



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 2/87 (2%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            + ++P  +        V  G+    ECK+    +  L VEW+K+G+ +T   + +     
Sbjct: 6626 MVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPE--LSVEWYKDGKLLTSSQKHKFSFYN 6683

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVG 1526
               +L I+ +  +D+G YT +  N VG
Sbjct: 6684 KISSLRILSVERQDAGTYTFQVQNNVG 6710



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/69 (27%), Positives = 37/69 (53%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P+L VEW ++G  + +S +          +L +  V  +D+GTYT +  N +G++  +
Sbjct: 6656 GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCT 6715

Query: 1798 STLFVQSKA 1806
            + + V  +A
Sbjct: 6716 AVVDVSDRA 6724



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L+N   +  G +   +C++   G   + V WF  +  I   ++   T      +
Sbjct: 6727 PSFTRRLKNTGGVL-GASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCT 6783

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + ++ +   D G Y C A+N+ G
Sbjct: 6784 LQLNSLDSSDMGNYTCVAANVAG 6806



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 1/70 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P F   P ++ V  GE A F C VTG    R+ W  +   I  G  Y +T  G   H  I
Sbjct: 7198 PFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRI 7257

Query: 4170 PKTRQYDTGK 4179
             K  + D+G+
Sbjct: 7258 LKVGKGDSGQ 7267



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            ++I W  + K +  G  + +T       L ++ V + DSG YTC+A N  G+   S+ + 
Sbjct: 7227 MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLS 7286

Query: 3003 CTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEP 3036
                   +++ +  K  +  E IQ LE  +   P
Sbjct: 7287 VKEPPKFVKKLEASKVAKQGESIQ-LECKISGSP 7319



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 2/99 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  P + I   + +T   G     E  +   G P +  +W K+G+ + A S+    F   
Sbjct: 7568 VLEPARIIEKPEPMTVTTGNPFALECVV--TGTPELSAKWFKDGRELSADSKHHITFINK 7625

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
              SL +    + D G Y+    ++ G +     +HV+ R
Sbjct: 7626 VASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDR 7664



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L  + N   G     ECRV       +++ WF +G +I +G + +++       
Sbjct: 7668 PSFIRKLKDV-NAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L++      D+G Y C A N  G    +  L V
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 7757



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 4/105 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKD-GRPVEASSRITTFFNFGYV 967
            P F   + D IS   G     +  +E  G   + V W KD G  V  S  I   ++    
Sbjct: 8419 PRFVKKLSD-ISTVVGKEVQLQTTIE--GAEPISVVWFKDKGEIVRESDNIWISYSENIA 8475

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
             L    V   +AG YTC+  N  G     A L+++    I+ + +
Sbjct: 8476 TLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPE 8520



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/116 (22%), Positives = 50/116 (43%), Gaps = 3/116 (2%)

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRN 1749
            Q+++ +  Q   A   V+  A +   P + I+V        E  +   G P+L  +W ++
Sbjct: 8493 QIKNDAGMQECFATLSVLEPATIVEKP-ESIKVTTGDTCTLECTV--AGTPELSTKWFKD 8549

Query: 1750 GVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            G  + + N+           L +  V P DSG Y+    N +G+   +++L V  +
Sbjct: 8550 GKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 8605



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/87 (26%), Positives = 33/87 (37%), Gaps = 2/87 (2%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F+ +     V     V F   V  K  P   + W++    L  G R     +  
Sbjct: 8698 VREPPSFVQKPDPMDVLTGTNVTFTSIV--KGTPPFSVSWFKGSSELVPGDRCNVSLEDS 8755

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGE 3912
               L++  V    SGEY C   N+ G+
Sbjct: 8756 VAELELFDVDTSQSGEYTCIVSNEAGK 8782



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/88 (26%), Positives = 35/88 (39%), Gaps = 3/88 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +  P FVQ   +P  V  G N+     ++  G P   V WF     +  G R     +  
Sbjct: 8699 REPPSFVQK-PDPMDVLTGTNVTFTSIVK--GTPPFSVSWFKGSSELVPGDRCNVSLEDS 8755

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSA 1261
               L++    ++ +GEYT    N  G A
Sbjct: 8756 VAELELFDVDTSQSGEYTCIVSNEAGKA 8783



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 3/91 (3%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            F   L  Y  + +G+ + LE        P + + W KNG+ +T   R   T       L 
Sbjct: 8797 FVKRLNDYS-IEKGKPLILEGTFTGT--PPISVTWKKNGINVTPSQRCNITTTEKSAILE 8853

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            I S   +D+G Y C   N  G+   +A I I
Sbjct: 8854 IPSSTVEDAGQYNCYIENASGKDSCSAQILI 8884



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F   L  +D +  G++A F+C +   G   +KV W ++ + I    +   ++      
Sbjct: 9080 PFFDIRLAPVDAVV-GESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAH 9136

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            +T+  V   D G Y C A N +G+
Sbjct: 9137 LTVLKVDKGDSGQYTCYAVNEVGK 9160



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 2638  VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
             V++ P+  T       + EG    LE +V      N K++WFKNG  +    + +   D 
Sbjct: 13207 VKEPPVEFTKPLEDQTVEEGATAVLECEVSRE---NAKVKWFKNGTEILKSKKYEIVADG 13263

Query: 2698  GLVTLSINSLRNDDSGIYTCKA 2719
              +  L I+    +D   YTC A
Sbjct: 13264 RVRKLVIHDCTPEDIKTYTCDA 13285



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 3281  PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
             P +F+  ++D T + E   A F  +L         V+W+ NG+++  G +Y+   D  I 
Sbjct: 13749 PTEFVEHLEDQT-VTEFDDAVFSCQL---SREKANVKWYRNGREIKEGKKYKFEKDGSIH 13804

Query: 3341  ILDILYCYEENSGEYECVATNKLGR 3365
              L I  C  ++  EY C   ++  R
Sbjct: 13805 RLIIKDCRLDDECEYACGVEDRKSR 13829



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 17/69 (24%), Positives = 34/69 (49%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G   +    ++G P P++TW K    L    +  I      +T+ + ++++SD+G Y
Sbjct: 14629 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 14688

Query: 337   TLLAENPNG 345
              + A N  G
Sbjct: 14689 IIEAVNVCG 14697



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 1711  PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
             P   +   DI V E +          V  P   V W ++G  ++AS+RLT  +D     L
Sbjct: 15314 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHL 15371

Query: 1771  NMKYVNPEDSGTYTCRAINELGEAVTS 1797
              +      D+G YT    N+LG A  S
Sbjct: 15372 EVPKSVRADAGIYTITLENKLGSATAS 15398



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 8/77 (10%)

Query: 2388  IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE---DSSRITK---THDFGYVSMTISHV 2441
             ++ G+  H    +   G P  K+EW +NE +IE   D+ +ITK   +       ++I   
Sbjct: 16337 VKAGEPVHIPADV--TGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 16394

Query: 2442  RDEDEGVYMCRASNLLG 2458
               ED+G Y   ASN LG
Sbjct: 16395 VREDKGTYTVTASNRLG 16411



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/108 (22%), Positives = 47/108 (43%), Gaps = 6/108 (5%)

Query: 381   ERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
             E + + ++   P+ +    + +++ +  G   R    + G P+P+VTW   DR       
Sbjct: 18132 EPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA--PTK 18189

Query: 438   HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
              +I V   G+  L I N    D G+ +    N +G      ++ V++K
Sbjct: 18190 ARIDVTPVGS-KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 18236



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 4512  VPPSFTLTAQN---VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568
             VPP   L+      + V +G  V LD  V G     V W K+G  ++P    K+  +   
Sbjct: 20218 VPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL 20277

Query: 4569  YTLLILEAYPQDSGKYECVAINSAG 4593
              TL +     +DSG Y   A NS+G
Sbjct: 20278 CTLELFSVNRKDSGDYTITAENSSG 20302



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 485   KEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             ++ V APK    V+   T+ ++ GE   L A   G P P + W KDG  +    +L I  
Sbjct: 22380 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 22439

Query: 542   DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                ++ L    +   D+  Y  TA N  G
Sbjct: 22440 ADFSTNLVNKDSTRRDSGAYTLTATNPGG 22468



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/68 (29%), Positives = 30/68 (44%)

Query: 503   REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             + GE V +     G P P +TW+KD   +  +    I     +S L IP+   +D   Y 
Sbjct: 28211 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 28270

Query: 563   CTAQNVAG 570
              T +N  G
Sbjct: 28271 LTIENGVG 28278



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             +  G+++ ++  ++  G P  RV WF +G  +      +     G  +L +  AT    G
Sbjct: 28897 IKSGESLRIKALVQ--GRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28954

Query: 1249  EYTVRAVNHLGSAHTSAIVRV 1269
              YTV A N  GSA     V+V
Sbjct: 28955 VYTVEAKNASGSAKAEIKVKV 28975



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/76 (26%), Positives = 32/76 (42%)

Query: 4637  GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
             G        I G+P P V W   +  +K +    ++ T D  TL + ++   D G Y   
Sbjct: 29589 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 29648

Query: 4697  AYNSAGRVTVAAKLKV 4712
               N+AG  T +  + V
Sbjct: 29649 LENTAGVKTFSVTVVV 29664



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 1846 FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALD 1905
            F+ +L    ++ E  S   EC + P    N+  +WY N   L+S  +Y  ++  G   L 
Sbjct: 2269 FVKELQD-IEVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 1906 ILTVYGEDSGEYT 1918
            +  V  ED GEY+
Sbjct: 2325 VKDVTKEDQGEYS 2337



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            +   TV ES+   FEC V    +P  + EW R+GK LP  +  R+  D     L I    
Sbjct: 2626 LTDQTVAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATK 2682

Query: 3896 AEDSGEY 3902
             +D GEY
Sbjct: 2683 LDDIGEY 2689



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            ++E Q A +EC +    +P+ + EW  +GK L   +  R+ +D     L I     +D G
Sbjct: 2631 VAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIG 2687

Query: 1916 EYTCKAINNLGQA---VSSIRLNVQSKESIIRDSQ 1947
            EYT K   +   A   V ++++    K   + ++Q
Sbjct: 2688 EYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQ 2722



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDI-LYCYEENSGEYECVATNKLGRDSTKANL 3372
            +V W++  K +P   +++   D     L I     E++ GEY C A N  G+ +T A L
Sbjct: 4317 EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4375



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 3575 AHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
            A F C +   +  ++R +WF  G+ +    +    +      LEI      D G YTCKA
Sbjct: 4400 AKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 4457

Query: 3635 TNRHGEATVSCKLQV 3649
            +N +G  + +  L V
Sbjct: 4458 SNEYGSVSCTATLTV 4472



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 3/122 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +T    P F     ++ T  G      C +   G   +   W  +G  +     ++ +  
Sbjct: 4472 VTEAYPPTFLSRPKSLTTFVGKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWKISDA 4529

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH-PSGLEKIQY 1423
             +   L+L ++  +D GVY+C+A+N+ G  +    L +I K   I E +   S + K  +
Sbjct: 4530 ENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVH 4589

Query: 1424 LE 1425
            LE
Sbjct: 4590 LE 4591



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
            +K+ W+ N++ +K  S+   +       L +     EDSG Y C A N  G    S I I
Sbjct: 5256 IKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI 5315

Query: 1669 VHSKKSIYLESQ 1680
            V  K+S Y   +
Sbjct: 5316 V--KESPYFTKE 5325



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/90 (23%), Positives = 41/90 (45%), Gaps = 7/90 (7%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIP--VGDPTLKVEWFRNEKLIEDSSRITKT 2428
            + ++ P FT+  + I+ ++E     +D  L+    G P  ++ WF++  ++    +    
Sbjct: 5315 IVKESPYFTKEFKPIEVLKE-----YDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTF 5369

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                 VS+ I      D G Y CR +N +G
Sbjct: 5370 IQDHLVSLQILKFVAADAGEYQCRVTNEVG 5399



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/98 (22%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            S ++P   T     I + +G  A  + +    G   +  +W KDG+ +   S+       
Sbjct: 5501 SVKEPATITEEAVSIDVTQGDPATLQVKFS--GTKEITAKWFKDGQELTLGSKYKISVTD 5558

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
                L I S    D+G YT    N +G+++  A + ++
Sbjct: 5559 TVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVL 5596



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 5/104 (4%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY-DF 4028
            K+PP FV + QSQ        T+ + +    G   M ++WF + K L H      ++ D 
Sbjct: 5692 KEPPYFVEKPQSQDV---NPNTRVQLKALVGGTAPMTIKWFKDNKEL-HSGAARSVWKDD 5747

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
               ++        DSG Y+C+ +N  G   +KA +     P  +
Sbjct: 5748 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFI 5791



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 15/65 (23%), Positives = 34/65 (52%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G + + ++W KD + + + +  + + +    +L + +    D+G Y C+  N +G AT+ 
Sbjct: 5720 GTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSK 5779

Query: 997  ANLTI 1001
            A L +
Sbjct: 5780 ATLFV 5784



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/70 (25%), Positives = 33/70 (47%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            + I+W+ + K L  G+   +  D    +L+L      DSG Y C+  N  G A + +T++
Sbjct: 5724 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 5783

Query: 3003 CTSKDNLIER 3012
                   I++
Sbjct: 5784 VKEPPQFIKK 5793



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/62 (27%), Positives = 32/62 (51%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            MT++W+ + K++ S      + D    +L++ + +A DSG Y     N  G A   A++ 
Sbjct: 5724 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 5783

Query: 1135 VE 1136
            V+
Sbjct: 5784 VK 5785



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/91 (20%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P+++  + A   +  G    LE ++     P++++ W+ N   L    ++++T       
Sbjct: 6350 PKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDSVAV 6407

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + + ++   DSG + C+A N  G    S+ V
Sbjct: 6408 IQMNNLSTEDSGDFICEAQNPAGSTSCSTKV 6438



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/87 (22%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++ + PVF+     +   +N     E  L   G P   V W ++   + +S +       
Sbjct: 6439 IVKEPPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKN 6496

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELG 1792
             + ++++  V+  D G Y C+A NE+G
Sbjct: 6497 FHTSIHILNVDTSDIGEYHCKAQNEVG 6523



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/75 (22%), Positives = 34/75 (45%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +  P  K+ W+   + L +G R  +  +     L+L ++    SG YTC   N  G+A  
Sbjct: 6844 RGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASC 6903

Query: 2998 SSTVYCTSKDNLIER 3012
            ++ ++       ++R
Sbjct: 6904 TTRLFVKEPAAFLKR 6918



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 1/69 (1%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q +    P++ + WY     L     ++        TL    V   DSG YTCKA N  G
Sbjct: 7026 QCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIG 7085

Query: 2994 EAFTSSTVY 3002
             A +S TV+
Sbjct: 7086 TA-SSKTVF 7093



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F R L+D+ E   G       +L   S P ++V WY+DG  +     + + F     +
Sbjct: 7102 PSFARQLKDI-EQTVGLPVTLTCRLNG-SAP-IQVCWYRDGVLLRDDENLQTSFVDNVAT 7158

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            L I+      +G Y+  A N LG A S+A  R+ AR
Sbjct: 7159 LKILQTDLSHSGQYSCSASNPLGTASSSA--RLTAR 7192



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 2240 SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY 2299
            +PP F T+        +G     +C++     P   + +  + K ++++ +F IT     
Sbjct: 7383 APPVF-TQKPSPVGALKGSDVILQCEISGT--PPFEVVWVKDRKQVRNSKKFKITSKHFD 7439

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISM 2332
             SL I +    D GEY  KA N +G  T + S+
Sbjct: 7440 TSLHILNLEASDVGEYHCKATNEVGSDTCSCSV 7472



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 33/148 (22%), Positives = 68/148 (45%), Gaps = 5/148 (3%)

Query: 1793 EAVTSSTLFVQSKASLQLESQHESALQK-IQQLEDSSRYQRREDVEVAVNQAPRFITQLN 1851
            E+  +   F+ + A+LQL S   S   K I Q+++ +    RE   V     P  I +  
Sbjct: 7521 ESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGM--RECSAVLTVLEPARIIEKP 7578

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
             P  ++ G     EC +   P+  +  +W+ +G+ L +  ++  +     A+L I     
Sbjct: 7579 EPMTVTTGNPFALECVVTGTPE--LSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM 7636

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
             D G Y+ +  N++G++  ++ ++V  +
Sbjct: 7637 SDKGLYSFEVKNSVGKSNCTVSVHVSDR 7664



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 2/94 (2%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   +E  + + V  G P   +C V   G P +   WF +GR  +  S+ H        +
Sbjct: 7571 PARIIEKPEPMTVTTGNPFALECVV--TGTPELSAKWFKDGRELSADSKHHITFINKVAS 7628

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            L I      D G Y+    N  G +  T  +  S
Sbjct: 7629 LKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVS 7662



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F + L++++ I  G +   +CR+   G   + V WF++   I    +   +      +
Sbjct: 7668 PSFIRKLKDVNAIL-GASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 7724

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + +S +   D G+Y C A+N+ G
Sbjct: 7725 LNLSLLEPSDTGIYTCVAANVAG 7747



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            E P F         L  G+S  F+  +       +K+ W  + +++  G  Y+       
Sbjct: 8136 EVPPFFDLKPVSVDLALGESGTFKCHVTGT--APIKITWAKDNREIRPGGNYKMTLVENT 8193

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L +L   + ++G+Y C A+N  G+DS  A+L
Sbjct: 8194 ATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHL 8226



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 4/97 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            P      P  + ++   +   EC +    + S +  WF +GK L + ++ K I+ F  V 
Sbjct: 8512 PATIVEKPESIKVTTGDTCTLECTVAGTPELSTK--WFKDGKELTSDNKYK-ISFFNKVS 8568

Query: 3617 -LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             L+I  V   D+G+Y+ +  N  G+ + +  LQV  R
Sbjct: 8569 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 8605



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/72 (23%), Positives = 32/72 (44%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P + + W+  G  +  G +++ T       L +  + E DSG YTC A N  G    S+ 
Sbjct: 8636 PPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAP 8695

Query: 3001 VYCTSKDNLIER 3012
            +      + +++
Sbjct: 8696 LTVREPPSFVQK 8707



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 2/84 (2%)

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            ++V W  + R ++ G +++ +Y      L +L     D+G Y C A N VG+   T+ + 
Sbjct: 9109 IKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLN 9168

Query: 2069 VDAKSGLYLDTLDEQRLKKIQELE 2092
            +  K  L   +  ++  + ++E E
Sbjct: 9169 I--KERLIPPSFTKRLSETVEETE 9190



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+ L E  +    C+    N  S   EWF NG+ L    R KT  +     L I  V   
Sbjct: 9680 DVTLKEGQTCTMTCQFSVPNVKS---EWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAE 9736

Query: 3626 DAGLYTCK 3633
            D G YTCK
Sbjct: 9737 DQGQYTCK 9744



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 9/122 (7%)

Query: 1825 EDSSRYQ-RREDVEVA----VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879
            ED  +Y  + ED+E +    +   P   T+      +SE QSA +EC +  + D    V 
Sbjct: 9736 EDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVS-FDDAI--VT 9792

Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA-INNLGQAVSSIRLNVQS 1938
            WY     L    +Y   ND     + I  V  +D G Y+  A +   G+A S+  L + +
Sbjct: 9793 WYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTT 9852

Query: 1939 KE 1940
            KE
Sbjct: 9853 KE 9854



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 5/91 (5%)

Query: 626   PPGEEDRVYP----PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIE-WLKNGQSIE 680
             PP E    Y     P +F+  +K +   E   +      E +  P+  I  W+K+G +I 
Sbjct: 12027 PPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIR 12086

Query: 681   ASSRFTSIFRFGYISLDMLSLNIQDSGEYTC 711
              S +   I       L ++ + + D+GEYTC
Sbjct: 12087 ESPKHRFIADGKDRKLHIIDVQLSDAGEYTC 12117



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 2380  QPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTIS 2439
             +PL+++  +  G+TA FDC L     P   VEW+   K +E S ++    +    ++T+ 
Sbjct: 13127 RPLKDV-TVTAGETATFDCELSYEDIP---VEWYLKGKKLEPSDKVVPRSEGKVHTLTLR 13182

Query: 2440  HVRDEDEG 2447
              V+ ED G
Sbjct: 13183 DVKLEDAG 13190



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 5/79 (6%)

Query: 3557  PP--EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
             PP  EF    +DL + E   A FEC L   N    +V+WF +G  +  G +   I+    
Sbjct: 13298 PPHVEFLRPLTDLQVREKEMARFECELSREN---AKVKWFKDGAEIKKGKKYDIISKGAV 13354

Query: 3615  VILEIGGVYQRDAGLYTCK 3633
              IL I      D   Y+C+
Sbjct: 13355 RILVINKCLLDDEAEYSCE 13373



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)

Query: 4113  FVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
             F+S P  + + EGE A F C ++    P V W  +  T+ +G +Y +  DG
Sbjct: 13481 FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADG 13530



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 14/123 (11%)

Query: 4481  FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
             F   A N  G +K SA +   + +R      +PPS  L  + + V  G  V +  K+ G 
Sbjct: 17016 FRVKAVNAAGVSKPSATVGPCDCQRPD----MPPSIDLK-EFMEVEEGTNVNIVAKIKGV 17070

Query: 4541  KPIDVYWLKNGKKVQPDIRNKILEE--------DGTYTLLILEAYPQDSGKYECVAINSA 4592
                 + W K   K +PD +  +L +        D T TL+I ++   D+G Y   A+N+ 
Sbjct: 17071 PFPTLTWFKAPPK-KPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 17129

Query: 4593  GEA 4595
             G A
Sbjct: 17130 GTA 17132



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 2230  TRIEVE-EPKISPPRFVTELRGTTH--VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ 2286
             T I +E + K+ PP    +++      V  G T  F   +  V  P  +  +  +G  ++
Sbjct: 18422 TTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIK 18479

Query: 2287  SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             +   + +  D     L I++C+  D GEY +   NA G  T A+ +TV
Sbjct: 18480 TDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 18527



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 5/105 (4%)

Query: 3685  ITIE-DEKPNPPRFTVEIK--DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
             I IE  EK  PP   +++K  + + V  G  V F   +  V  PT +  W  +G    T 
Sbjct: 18424 IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTD 18481

Query: 3742  SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
                    D     L I     RD GEY    +N  GS T    +T
Sbjct: 18482 EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 18526



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 3/86 (3%)

Query: 4511  IVPPSFTLTAQNVN---VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567
             +VPPS  L  + +    V +G  VR    + G       W  +G +++ D    +  ++ 
Sbjct: 18432 LVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNF 18491

Query: 4568  TYTLLILEAYPQDSGKYECVAINSAG 4593
             +  L I     +D+G+Y+    N+AG
Sbjct: 18492 SSVLTIKNCLRRDTGEYQITVSNAAG 18517



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/70 (27%), Positives = 29/70 (41%)

Query: 4001  GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
             G P   + W   GK L+ + R   I D   V +        D G+Y+  A N  G  +  
Sbjct: 18861 GRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 18920

Query: 4061  AVIKTTGKPG 4070
             A++    +PG
Sbjct: 18921 AIVNVLDRPG 18930



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/80 (26%), Positives = 30/80 (37%)

Query: 4633  IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             +  E         I GKP P+V W KG+  +       +  +A   TL + +    D G 
Sbjct: 20920 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 20979

Query: 4693  YKCVAYNSAGRVTVAAKLKV 4712
             Y     N AG       +KV
Sbjct: 20980 YTITLKNVAGTKEGTISIKV 20999



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 2905  DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLT- 2963
             D E PK +  +       L  G+   LE  V  +  P +  EW  +GK LE  ++ ++  
Sbjct: 22382 DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTM--EWSKDGKELEGTAKLEIKI 22439

Query: 2964  SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
             +DF    L   D   RDSG YT  A N  G A
Sbjct: 22440 ADFS-TNLVNKDSTRRDSGAYTLTATNPGGFA 22470



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/69 (27%), Positives = 31/69 (44%)

Query: 1737  VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
             +G P   V W ++ VP++ + R+          L +K    ED G Y  +  N  GEA+ 
Sbjct: 23099 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 23158

Query: 1797  SSTLFVQSK 1805
             +  + V  K
Sbjct: 23159 TLNVIVLDK 23167



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/86 (20%), Positives = 34/86 (39%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             +  + EV   G P P I W ++  P+K +    +      + L I++   +D   +    
Sbjct: 24172 QDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITV 24231

Query: 4486  ENRGGTAKCSANLVVEEKRRQGRGGI 4511
              N  G    S  +V  +K    +G +
Sbjct: 24232 ANVVGQKTASIEIVTLDKPDPPKGPV 24257



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/61 (34%), Positives = 29/61 (47%)

Query: 2803  PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
             P   I W  + +PL   TR       +   L I    ++D G YT  ATNS G+AT + S
Sbjct: 25266 PRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLS 25325

Query: 2863  L 2863
             +
Sbjct: 25326 V 25326



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 16/78 (20%), Positives = 34/78 (43%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             EQ + +V F G P   + W ++   +K +    + +  T + L I++   ED   +    
Sbjct: 26337 EQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 26396

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N  G+      ++V ++
Sbjct: 26397 SNSAGSITVPITIIVLDR 26414



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             G  V L A +  +  P   IEW+K+   L T A +       L ++ I      +SG Y 
Sbjct: 27814 GTSVKLRAGISGKPAPT--IEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYE 27871

Query: 2717  CKATNLLGEAVSTASIKIEDR 2737
              K  N +G A +T  ++I D+
Sbjct: 27872 LKLRNAMGSASATIRVQILDK 27892



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 2/99 (2%)

Query: 4606  PATKDKPKPQTKAANAPP-EIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
             P   ++P        AP  ++   L+  ++A+ G+ ++      G+P PTV W K +K +
Sbjct: 28180 PIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL 28239

Query: 4664  KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                  + +  T     L I +    D G Y     N  G
Sbjct: 28240 GSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 28278



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/96 (28%), Positives = 38/96 (39%)

Query: 4522  NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
             +V   +G+ V++     G  P  V W K+ K +  D R  I   D +  L I +    D+
Sbjct: 28207 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDT 28266

Query: 4582  GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
             GKY     N  GE +     V  L       K Q K
Sbjct: 28267 GKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVK 28302



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V R  PV  + ++ ++ +  G  A F C +     P ++ +WF+  + I +S + +    
Sbjct: 4378 VKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSS 4434

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                S+ I   +  D G Y C+ASN  G
Sbjct: 4435 KYISSLEILRTQVVDCGEYTCKASNEYG 4462



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/87 (20%), Positives = 38/87 (43%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            + E P F K ++ A++  G    L+  ++        + W+ + + ++   +++      
Sbjct: 4754 IKEPPSFIKTLEPADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLFSQKS 4811

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
             V L+I    + D G Y C   N VG+
Sbjct: 4812 LVCLEIFSFNSADVGEYECVVANEVGK 4838



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/84 (23%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F ++  +  D+  G      C V   G     I WF + +   +  +    +    +
Sbjct: 4757 PPSF-IKTLEPADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLFSQKSLV 4813

Query: 3754 ALDIDYIYARDAGEYTCRATNKWG 3777
             L+I    + D GEY C   N+ G
Sbjct: 4814 CLEIFSFNSADVGEYECVVANEVG 4837



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 17/59 (28%), Positives = 24/59 (40%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ 992
            E  G     + W KD + + +S +   F     V L I S    D G Y C   N +G+
Sbjct: 4780 EVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 4838



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/115 (21%), Positives = 48/115 (41%), Gaps = 3/115 (2%)

Query: 3264 ESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGK 3323
            E+  G+Q         EP K I + + + ++  G  A  E  +     P+LK +W+ +G+
Sbjct: 4926 ENEAGSQTSVGELIVKEPAKIIERAE-LIQVTAGDPATLEYTVAGT--PELKPKWYKDGR 4982

Query: 3324 KLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
             L    +YR      +  L        +SG+Y    +N++G  S +       ++
Sbjct: 4983 PLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRD 5037



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 3/99 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   +E  + I V  G P   +  V   G P ++  W+ +GRP     +           
Sbjct: 4943 PAKIIERAELIQVTAGDPATLEYTV--AGTPELKPKWYKDGRPLVASKKYRISFKNNVAQ 5000

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            L        D+G+YT   +N+ GS++     T    RDI
Sbjct: 5001 LKFYSAELHDSGQYTFEISNEVGSSSCETTFTV-LDRDI 5038



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 2924 VEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGI 2983
            ++G  + LE  V   +   + I+W+ + + +    ++K +       L++  +   DSG 
Sbjct: 5614 IKGSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGT 5671

Query: 2984 YTCKAYNKRGEAFTSSTVYCTSKDNLIERTQ 3014
            YTC A NK G    S  +        +E+ Q
Sbjct: 5672 YTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 5702



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/113 (22%), Positives = 44/113 (38%), Gaps = 3/113 (2%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            I+  V   P F+   K +E V++   V  EC++        +V W KN + +    ++  
Sbjct: 5874 IELKVKEPPTFIRELKPVE-VVKYSDVELECEVTGTPP--FEVTWLKNNREIRSSKKYTL 5930

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
                    L I      D+G Y C   N  G+   S R+  +     ++  +N
Sbjct: 5931 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIEN 5983



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/53 (35%), Positives = 26/53 (49%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724
            P + I W K+   L     +  +F   + TL I S+ N  SG YTC+A N  G
Sbjct: 6002 PPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESG 6054



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 17/63 (26%), Positives = 29/63 (46%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P LKV+W  +GK +     F    +       I     +DSG+Y  +  N++G +   A 
Sbjct: 6095 PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 6154

Query: 3510 MKV 3512
            ++V
Sbjct: 6155 LRV 6157



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/71 (25%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 2924 VEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGI 2983
            V G  +H+E +V       +  +W+ +GK +   ++++L      V+L++ ++   D+  
Sbjct: 6176 VLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN 6233

Query: 2984 YTCKAYNKRGE 2994
            YTCK  N  G+
Sbjct: 6234 YTCKVSNVAGD 6244



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 3578 ECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATN 3636
            EC++    + S  VEW+ +GK LLT S+    + +  +  L I  V ++DAG YT +  N
Sbjct: 6651 ECKVAGTPELS--VEWYKDGK-LLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQN 6707

Query: 3637 RHGEATVSCKLQVKGR 3652
              G+++ +  + V  R
Sbjct: 6708 NVGKSSCTAVVDVSDR 6723



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 2/93 (2%)

Query: 1967 AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF 2026
            AV D S     P F + +KN     G    LE  +       + V W+     +  G ++
Sbjct: 6716 AVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVA--GSSPISVAWFHEKTKIVSGAKY 6773

Query: 2027 KTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            +TT+      L +    + D G Y C A N  G
Sbjct: 6774 QTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAG 6806



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/59 (30%), Positives = 28/59 (47%)

Query: 2141 LTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
            + + W+ +G  +R     +T+       L IL T    SG Y C A+N LG A ++  L
Sbjct: 7131 IQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 7189



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F     +ID I  G++A F+C +   G   +++ W ++ K I      T T    
Sbjct: 7195 KKSPFFDIKPVSIDVIA-GESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTITCVGN 7251

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459
               + I  V   D G Y C+A+N +G+
Sbjct: 7252 TPHLRILKVGKGDSGQYTCQATNDVGK 7278



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/68 (26%), Positives = 32/68 (47%)

Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
            R  P  K++WFK    L  G     + +  +  L +  ++  +SG Y+C  TN  G A  
Sbjct: 7785 RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASC 7844

Query: 2729 TASIKIED 2736
            T  + +++
Sbjct: 7845 TTHLFVKE 7852



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 6/92 (6%)

Query: 2911 PEWIIPIAAEH-QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            P +I P+  EH + V G+   L+ +V+    P+++I WY     L     +K+       
Sbjct: 7947 PYFIEPL--EHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVA 8002

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            +L +  V   D G Y+CKA N  G A  SS V
Sbjct: 8003 SLVINKVDHSDVGEYSCKADNSVG-AVASSAV 8033



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 3/82 (3%)

Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631
            ++T   P     L++V +KEGQ      +    S   +K EW+ N + LK   R      
Sbjct: 9666 KLTVIEPAWERHLQDVTLKEGQTCTMTCQF---SVPNVKSEWFRNGRILKPQGRHKTEVE 9722

Query: 1632 FGFVALDIMSCLPEDSGTYTCR 1653
                 L I     ED G YTC+
Sbjct: 9723 HKVHKLTIADVRAEDQGQYTCK 9744



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 4091  EASWQVTPEQVVEESKAR-CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
             E S+Q    +     K +  P +F++    V V E + A+F C V+  PK    WL    
Sbjct: 12746 EVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQ 12804

Query: 4150  TIVNGSRYKLTYDGMYHFDIPKTRQYD 4176
              I    R++L  DG  H  + K+  ++
Sbjct: 12805 EITGDDRFELIKDGTKHSMVIKSAAFE 12831



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 6/79 (7%)

Query: 3281  PP--KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
             PP  +F+  + D+ ++ E + A FE  L      + KV+WF +G ++  G +Y       
Sbjct: 13298 PPHVEFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGA 13353

Query: 3339  IVILDILYCYEENSGEYEC 3357
             + IL I  C  ++  EY C
Sbjct: 13354 VRILVINKCLLDDEAEYSC 13372



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 5/78 (6%)

Query: 3829  PP--KFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
             PP  +F+  +    V E E  RFEC +  +E+ K  ++W+++G  +  G +Y  +     
Sbjct: 13298 PPHVEFLRPLTDLQVREKEMARFECELS-RENAK--VKWFKDGAEIKKGKKYDIISKGAV 13354

Query: 3887  VSLDILYVYAEDSGEYIC 3904
               L I     +D  EY C
Sbjct: 13355 RILVINKCLLDDEAEYSC 13372



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 3/91 (3%)

Query: 3695  PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
             P   +E  D I V EG  +        V  PT  + W  +G+      R+   ND     
Sbjct: 15314 PTIDLETHDII-VIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAH 15370

Query: 3755  LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             L++      DAG YT    NK GSAT +  +
Sbjct: 15371 LEVPKSVRADAGIYTITLENKLGSATASINV 15401



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 60    PITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR---KKAPLVECN 116
             P    RP  P P I  + F      +G N     K++G P P ++W +   KK    E  
Sbjct: 17035 PCDCQRPDMP-PSIDLKEFMEVE--EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPV 17091

Query: 117   KYSMRYNEQTGD--VSLLIKQIGPGDEGEYTCTARNQYGEA 155
              Y    N+   D   +L+I Q    D G YT TA N  G A
Sbjct: 17092 LYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTA 17132



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             E     +D I+++ G      AR++  G     + W K+G+ +    R+    +   V L
Sbjct: 18836 ELDVTCRDVITVRVGQTIRILARVK--GRPEPDITWTKEGKVLVREKRVDLIQDLPRVEL 18893

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
              IK     D G Y   A N+ G A  SA + ++ +
Sbjct: 18894 QIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDR 18928



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 3/91 (3%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKL--IKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
             V  G  I     + GKP P V W K      +  S   ++   AD     +++A   D G
Sbjct: 19140 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 19199

Query: 4692  DYKCVAYNSAGRVTVAAKLKV-TQPDQADNL 4721
              Y   A N+AG     A + V  +P    NL
Sbjct: 19200 KYVVTATNTAGSFVAYATVNVLDKPGPVRNL 19230



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             V  G N+ L+  +   G P   V W  +G  +      K         L++      D+G
Sbjct: 20234 VKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 20291

Query: 1249  EYTVRAVNHLGSAHTSAIVRVIER 1272
             +YT+ A N  GS   +  ++V+++
Sbjct: 20292 DYTITAENSSGSKSATIKLKVLDK 20315



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 6/79 (7%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS--LLIKQIGPGDEGE 143
             G N K E  + G P P V+W  KK    +  K + R N +T   S  L I +    D G 
Sbjct: 22007 GDNIKVEIPVLGRPKPTVTW--KKGD--QILKQTQRVNFETTATSTILNINECVRSDSGP 22062

Query: 144   YTCTARNQYGEAICSVYIQ 162
             Y  TARN  GE    + IQ
Sbjct: 22063 YPLTARNIVGEVGDVITIQ 22081



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/78 (24%), Positives = 35/78 (44%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  R E +  G P P ++W ++   ++ +   +I      + L+ +     DS  +   A
Sbjct: 22404 EAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 22463

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N GG AK   N+ V ++
Sbjct: 22464 TNPGGFAKHIFNVKVLDR 22481



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 4425  HEQARFEVEFD--GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFA 4482
             H    F+V+ D  G+P+P I+W + +  + N+   +I +    + L ++     DS  + 
Sbjct: 23483 HAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYI 23542

Query: 4483  AVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
               A+N  G    + N+ V ++     G +V
Sbjct: 23543 LKAKNVAGERSVTVNVKVLDRPGPPEGPVV 23572



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 1/60 (1%)

Query: 3174  VPVDD-PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             VP+   P   I W  +G P++ +TRI          L I  T   D G+Y     N  G+
Sbjct: 24178 VPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 24237



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 2/72 (2%)

Query: 3716  DCRVE-PV-GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT 3773
             D ++E PV G P   I W  +G P    +RV+         L I      D G+YT  AT
Sbjct: 25255 DLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTAT 25314

Query: 3774  NKWGSATTTAKI 3785
             N  G+AT    +
Sbjct: 25315 NSAGTATENLSV 25326



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 4/60 (6%)

Query: 96    RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQYGE 154
             +G P P V+W + +  L    +YS+   E T   SLL I Q+   D G+Y  T  N  GE
Sbjct: 28223 KGRPPPTVTWRKDEKNLGSDARYSI---ENTDSSSLLTIPQVTRNDTGKYILTIENGVGE 28279



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++  +++G       R+   G PT  V+++R+   I+ S     + +    S
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+    ED G Y   A+N +G
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVG 183



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 765  QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824
            Q  Q   F + LQD+   ++   A FE +    S+P ++V+WYKDG  +    +     +
Sbjct: 2169 QAKQLITFTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSD 2225

Query: 825  FGYVSLNIMHLRAEDAGSYT 844
                 L+I+ +   DA  Y+
Sbjct: 2226 RKVHFLSILTIDTSDAEDYS 2245



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 7/143 (4%)

Query: 3559 EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILE 3618
            EF     D+ + E+ S   EC + P N   +  +W+HN   L +  +    +  G   L 
Sbjct: 2268 EFVKELQDIEVPESYSGELECIVSPEN---IEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 3619 IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEET 3678
            +  V + D G Y+       G+ T +CKL++K R   IL+         G     +++ +
Sbjct: 2325 VKDVTKEDQGEYSFVI---DGKKT-TCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS 2380

Query: 3679 LHKREEITIEDEKPNPPRFTVEI 3701
            L   E + ++D +   P   V I
Sbjct: 2381 LESVEGVWMKDGQEVQPSDRVHI 2403



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 2/103 (1%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++ + P F   + D+     Q    +A +   G   + V W++    I    ++      
Sbjct: 4846 LLKEPPTFVKKVDDLIALGGQTVTLQAAVR--GSEPISVTWMKGQEVIREDGKIKMSFSN 4903

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
            G   L +  V     G YTC A NE G   +   L V+  A +
Sbjct: 4904 GVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKI 4946



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/51 (33%), Positives = 26/51 (50%)

Query: 2141 LTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            LTI WF   +++ +G     T +    +L++      DSGTY CK +N  G
Sbjct: 5162 LTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAG 5212



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F V+      +P+   V F   ++  G P  +I WF +     +G +     +    
Sbjct: 6256 PPSFLVKPGRQQAIPDS-TVEFKAILK--GTPPFKIKWFKDDVELVSGPKCFIGLEGSTS 6312

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             L++  + A   G+YTC  TN  GS + T  +
Sbjct: 6313 FLNLYSVDASKTGQYTCHVTNDVGSDSCTTML 6344



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 19/68 (27%), Positives = 28/68 (41%)

Query: 927  AHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
            A      E  G     V W KD R + +S +        + ++ I +V   D G Y C+A
Sbjct: 6459 AEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKA 6518

Query: 987  YNAIGQAT 994
             N +G  T
Sbjct: 6519 QNEVGSDT 6526



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 28/63 (44%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G     V W+KD + V  S +          +L I ++   D G Y C+A N +G  T S
Sbjct: 7410 GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCS 7469

Query: 997  ANL 999
             ++
Sbjct: 7470 CSV 7472



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 4/100 (4%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFN-GKQITSANRIQTY 1095
            VK  + PRF+  L  T+ ++ G +    A VE    ++  V W  + G+ I  +   +  
Sbjct: 7472 VKFKEPPRFVKKLSDTSTLI-GDAVELRAIVEGFQPIS--VVWLKDRGEVIRESENTRIS 7528

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
                   L + S  A +SG Y    +N AG  + SA +TV
Sbjct: 7529 FIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 7568



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/71 (28%), Positives = 33/71 (46%)

Query: 3445 TPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEA 3504
            T    P L  +W+ +GK L + ++++         L+I    P DSG Y     N  G+ 
Sbjct: 8535 TVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKD 8594

Query: 3505 VTTASMKVQGK 3515
              TAS++V  +
Sbjct: 8595 SCTASLQVSDR 8605



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 3/98 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K+   FV+ L N   + +GK + LE      G P + V W  NG +VT   R        
Sbjct: 8792 KAPAKFVKRL-NDYSIEKGKPLILEGTFT--GTPPISVTWKKNGINVTPSQRCNITTTEK 8848

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               L+I  +T  D G+Y     N  G    SA + ++E
Sbjct: 8849 SAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE 8886



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 35/137 (25%), Positives = 52/137 (37%), Gaps = 10/137 (7%)

Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
            +E  SG  D+ + +     PP F      + +S   SA  +C+L       + V W+   
Sbjct: 8869 IENASGK-DSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQL--AGTPEIGVSWYKGD 8925

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
              L   +  K         L    V   D+G Y CKA N  GE + S  L V+       
Sbjct: 8926 TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQ------- 8978

Query: 3658 EPQLPSHFKSGTESIQK 3674
            E +LP  F      +Q+
Sbjct: 8979 EQKLPPSFSRQLRDVQE 8995



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 9/101 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG---RPFATGSRVHTLNDF 3750
            PP F  +++  + V  G      C++   G P + + W+      RP  T  ++H  N+ 
Sbjct: 8887 PPYFVKQLEP-VKVSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRPTTT-YKMHFRNNV 8942

Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791
                L  + +   D+GEY C+A N  G  + +  +T   ++
Sbjct: 8943 A--TLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK 8981



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%)

Query: 4110  PPVFVSLP-DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
             PPV  + P +  TVEEG  A   C V+     +V W  NG  I+   +Y++  DG
Sbjct: 13210 PPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADG 13263



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 2775  VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
             VF  +L NI   E D I   C V     P  ++ W+  ++ +    RY+   +     L 
Sbjct: 13391 VFTKNLANIEVSETDTIKLVCEVSK---PGAEVIWYKGDEEIIETGRYEILTEGRKRILV 13447

Query: 2835  ITHTYEEDSGIYTCKATNSK 2854
             I + + ED+G Y C+  +S+
Sbjct: 13448 IQNAHLEDAGNYNCRLPSSR 13467



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 1871  YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
             YP P     W F  KVL++G R +      +A L I      D G YT K  N +     
Sbjct: 14348 YPRPT--ATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 14405

Query: 1931  SIRLNVQSKES 1941
              I +NV ++ S
Sbjct: 14406 EIDVNVIARPS 14416



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 6/120 (5%)

Query: 2219  KIRQLEAQGHSTRIEVEEPKISP-PRFVTELRGTTH---VFEGKTAHFECQVEPVHDPNL 2274
             ++R + A G S   E+ E  ++  P     +   TH   V EG+          V  P  
Sbjct: 15286 RVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT- 15344

Query: 2275  RIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              + ++ +GK ++++ R  +  D     L++   V  DAG Y++   N LG  T++I++ V
Sbjct: 15345 -VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 15403



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 1567  TDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKV---EWYHNNKPLKSG 1623
             +++ + V  + P C  ++ ++E  +      E+  IPV    + V    W+ + K +K+ 
Sbjct: 15299 SEISENVVAKDPDCKPTI-DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS 15357

Query: 1624  SRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
              R T  N+     L++   +  D+G YT    N LG A  S
Sbjct: 15358 DRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATAS 15398



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 4/102 (3%)

Query: 3684  EITIEDEKPNPPRFTVEI--KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
             E  I  +  +PP   +++  +D I V  G  +    RV+  G P   I W   G+     
Sbjct: 18822 ESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVK--GRPEPDITWTKEGKVLVRE 18879

Query: 3742  SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
              RV  + D   + L I      D G+Y   A N  G A  +A
Sbjct: 18880 KRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSA 18921



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 2/78 (2%)

Query: 1859  GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
             GQ+     R++  P+P+  + W   GKVL    R     D     L I      D G+Y 
Sbjct: 18850 GQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 18907

Query: 1919  CKAINNLGQAVSSIRLNV 1936
               A N+ G A  S  +NV
Sbjct: 18908 ISAKNSSGHAQGSAIVNV 18925



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
             G   +   +++G P P ++WT++   LV   +  +   +    V L IK+    D G+Y 
Sbjct: 18850 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI--QDLPRVELQIKEAVRADHGKYI 18907

Query: 146   CTARNQYGEA 155
              +A+N  G A
Sbjct: 18908 ISAKNSSGHA 18917



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/126 (22%), Positives = 48/126 (38%)

Query: 3121  YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
             +  +  N+ G+++     E V K   QKP     +  +  +K G +   E  V     P+
Sbjct: 19100 FRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPE 19159

Query: 3181  MKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             +      +   +  S R+K  +        +   +  D G+YV  A N  G     AT+N
Sbjct: 19160 VAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVN 19219

Query: 3241  CYGKGG 3246
                K G
Sbjct: 19220 VLDKPG 19225



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/60 (30%), Positives = 29/60 (48%)

Query: 1076  TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             TV W  +G  +  A  I+         L++ SV  +DSG YT+ A N++G    +  + V
Sbjct: 20253 TVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 20312



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 4/85 (4%)

Query: 782   LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI-TSIFNFGYVSLNIMHLRAEDA 840
             L+ G     EA ++    PTM  EW KDG+ +  ++++   I +F    +N    R  D+
Sbjct: 22400 LKAGEAFRLEADVSGRPPPTM--EWSKDGKELEGTAKLEIKIADFSTNLVNKDSTR-RDS 22456

Query: 841   GSYTVRAVNKLGEAISTASIRVAAR 865
             G+YT+ A N  G A    +++V  R
Sbjct: 22457 GAYTLTATNPGGFAKHIFNVKVLDR 22481



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/65 (32%), Positives = 29/65 (44%)

Query: 1608  TLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIA 1667
             T  V W+ +N PLK  +R    +      L I     ED G Y  +  N+ GEA+ +   
Sbjct: 23103 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV 23162

Query: 1668  IVHSK 1672
             IV  K
Sbjct: 23163 IVLDK 23167



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/172 (19%), Positives = 67/172 (38%), Gaps = 14/172 (8%)

Query: 1246  DTGEYTVRAVNHLGSAHT---SAIVRVIERSDIVTD-TQNEQAIEQIQLLEDAARRTKQ- 1300
             D G   ++ +  + + H+   S   RV     ++T+ TQ E+ + ++  + +  R   + 
Sbjct: 24084 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRS 24143

Query: 1301  -----VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                  V +D+ +   P    A  +     G ++ +E  +   G     + W  +G P+K 
Sbjct: 24144 LAVPIVAKDLVI--EPDVKPAFSSYSVQVGQDLKIEVPIS--GRPKPTITWTKDGLPLKQ 24199

Query: 1356  GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407
               R       D   L +   + +D G Y     N +G+   S  +  + K D
Sbjct: 24200 TTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD 24251



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 2/90 (2%)

Query: 3054  FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGT 3113
             F+D + ++ G+    EA +   G     IEW    K IE S R          +L +   
Sbjct: 24558 FRDTIVVNAGETFRLEADV--HGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDA 24615

Query: 3114  KTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
                D G Y  RA+N  G     V ++ +D+
Sbjct: 24616 IRIDGGQYILRASNVAGSKSFPVNVKVLDR 24645



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 16/70 (22%), Positives = 34/70 (48%)

Query: 276   KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335
             K + G   + +  +SG P P + W+K+ + L  +    +  T +  ++ +++  + +SG 
Sbjct: 27810 KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC 27869

Query: 336   YTLLAENPNG 345
             Y L   N  G
Sbjct: 27870 YELKLRNAMG 27879



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM-IHEGNNAVLLIGNTYE 4785
            +++  + EG    F  +++    P I W ++G  I     +QM   +   A L I     
Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLP 1356

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            ED G +T  A+   G    S KL V+
Sbjct: 1357 EDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 2122 KEGDR-AHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            KE D  A FEC     ++P + + W+ +G ++  G +YR   D     L IL     D+ 
Sbjct: 2186 KEKDTMATFECET---SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAE 2242

Query: 2181 TYMC 2184
             Y C
Sbjct: 2243 DYSC 2246



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            F + LQ+I+ + E  +   +C + P     ++ +W+ N+  ++ + + T T   G  ++T
Sbjct: 2269 FVKELQDIE-VPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2324

Query: 2438 ISHVRDEDEGVY 2449
            +  V  ED+G Y
Sbjct: 2325 VKDVTKEDQGEY 2336



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 910  EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
            EF+  IKD I + E   A FE     + +  + V+W+KD + ++ + RI          L
Sbjct: 3059 EFRKHIKD-IKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRL 3114

Query: 970  TIKSVTVHDAGHYTCRAYNAIGQA 993
             I S  + DAG YT  A   +  A
Sbjct: 3115 LIPSTRMSDAGKYTVVAGGNVSTA 3138



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/74 (24%), Positives = 35/74 (47%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P ++  W  +G  L     +K++       L+L ++  +D G+Y+CKA NK G     + 
Sbjct: 4505 PVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAE 4564

Query: 3001 VYCTSKDNLIERTQ 3014
            +    K + I+  +
Sbjct: 4565 LIIIDKPHFIKELE 4578



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            +KP F + L  P +    +  H E +V    D  +   W  +G +L  G  ++   +   
Sbjct: 4569 DKPHFIKELE-PVQSAINKKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKI 4625

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             TL+I      D+G Y+C A N AG
Sbjct: 4626 ATLEIPLAKLKDSGTYVCTASNEAG 4650



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 2/80 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L       G N   +C V  S     +I WF + K + S  +Y+     S V L+I
Sbjct: 4760 FIKTLEPADIVRGTNALLQCEV--SGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEI 4817

Query: 2836 THTYEEDSGIYTCKATNSKG 2855
                  D G Y C   N  G
Sbjct: 4818 FSFNSADVGEYECVVANEVG 4837



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 2/105 (1%)

Query: 2230 TRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA 2289
            ++  V E  +  P  + E      V  G  A  E  V     P L+ ++Y +G+ L ++ 
Sbjct: 4931 SQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGT--PELKPKWYKDGRPLVASK 4988

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
            ++ I+F      L        D+G+Y+ +  N +G  +   + TV
Sbjct: 4989 KYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTV 5033



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 1/78 (1%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   +++ W  + R ++ SS+    F      L +  V + D+G Y C A N  G    S
Sbjct: 5252 GTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS 5311

Query: 997  ANLTIVTKKDIIAESQHP 1014
             ++ IV +     +   P
Sbjct: 5312 -SIVIVKESPYFTKEFKP 5328



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/97 (21%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            V  ++PP F+ +I+S +SL    T  F+  L   G   + V W  +   +   +     +
Sbjct: 5407 VTLREPPSFIKKIESTSSL-RGGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTF 5463

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
            +    ++    +  +  G+Y+C+A N  G+    A++
Sbjct: 5464 ENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL 5500



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/82 (23%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
            +VT+G P  L+   +   + T +  W+ +G+ +  G ++K +       L I+    +D+
Sbjct: 5516 DVTQGDPATLQVKFSGTKEITAK--WFKDGQELTLGSKYKISVTDTVSILKIISTEKKDS 5573

Query: 2048 GTYMCKATNAVGEAVTTSSVKV 2069
            G Y  +  N VG +   + + V
Sbjct: 5574 GEYTFEVQNDVGRSSCKARINV 5595



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 7/95 (7%)

Query: 3280 EPPKFIT--QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            EPP F+   Q QDV      Q         P     + ++WF + K+L  G     + D 
Sbjct: 5693 EPPYFVEKPQSQDVNPNTRVQLKALVGGTAP-----MTIKWFKDNKELHSGAARSVWKDD 5747

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
                L++      +SG Y C  +N +G  ++KA L
Sbjct: 5748 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATL 5782



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI +I++ T        F+  V     P + I W ++ ++L         +     +
Sbjct: 5974 PPSFIKKIENTTTVLKSSATFQSTVAGS--PPISITWLKDDQILDEDDNVYISFVDSVAT 6031

Query: 3889 LDILYVYAEDSGEYICRAVNDFG 3911
            L I  V    SG Y C+A N+ G
Sbjct: 6032 LQIRSVDNGHSGRYTCQAKNESG 6054



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP F+ +     + +   +  F+A L     P  K++WF +  +L  G +     +   
Sbjct: 6255 EPPSFLVK-PGRQQAIPDSTVEFKAILKGT--PPFKIKWFKDDVELVSGPKCFIGLEGST 6311

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGG 3393
              L++       +G+Y C  TN +G DS    L  T     +   +  + ++ G
Sbjct: 6312 SFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAG 6365



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 4/112 (3%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP-IKTGHRFRPAY 1363
            + + + P+F   L+++  V G    L+  ++  G Q + V+W    +  I+     R  +
Sbjct: 6531 VKLKEPPRFVSKLNSLTVVAGEPAELQASIE--GAQPIFVQWLKEKEEVIRESENIRITF 6588

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              +   L      P ++G Y CQ  N  G       L V+ +  +I+E   P
Sbjct: 6589 VENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVL-EPAVIVEKAGP 6639



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P  + +     ++   ET   EC++A  G P + VEW+ +GK L    +    +     +
Sbjct: 6630 PAVIVEKAGPMTVTVGETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKISS 6687

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
            +    V  +D+G Y  +  N  G     AV+  + +
Sbjct: 6688 LRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDR 6723



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G N+ F   +  +  P  K+ WF   + L  G R     + +   L++ +     SG YT
Sbjct: 6834 GKNVTFTSVIRGT--PPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 6891

Query: 2848 CKATNSKGSATTSGSL 2863
            C  +N+ G A+ +  L
Sbjct: 6892 CVVSNNAGQASCTTRL 6907



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/87 (20%), Positives = 36/87 (41%), Gaps = 3/87 (3%)

Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431
            T + P F   L+ ++    G +    C++   G P + V W++ +  +  +         
Sbjct: 7002 TLEPPYFVTELEPLE-AAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTN 7058

Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLG 2458
               ++  + V   D G Y C+A N +G
Sbjct: 7059 NVATLVFNKVNINDSGEYTCKAENSIG 7085



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            PVFT   S +  L+ G +   +  ++ T  P  +V W  + K ++   +F+         
Sbjct: 7385 PVFTQKPSPVGALK-GSDVILQCEISGT--PPFEVVWVKDRKQVRNSKKFKITSKHFDTS 7441

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMK 3511
            L I      D GEY C+A N  G    + S+K
Sbjct: 7442 LHILNLEASDVGEYHCKATNEVGSDTCSCSVK 7473



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 17/62 (27%), Positives = 31/62 (50%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P  +V W  + K++ +  +++         L IL     + GEY C ATN++G D+   +
Sbjct: 7412 PPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCS 7471

Query: 3372 LK 3373
            +K
Sbjct: 7472 VK 7473



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/96 (25%), Positives = 39/96 (40%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F +   + EV  G  + L  T      P  +V+W+   R +  G     + +  
Sbjct: 7757 VQEPPSFEQTPDSVEVLPG--MSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 7814

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
               L++      ++G Y C  TN  G A  T+ + V
Sbjct: 7815 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV 7850



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/75 (21%), Positives = 34/75 (45%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +  P  K++W+   + L  G    ++ +     L+L +V   +SG Y+C   N  G A  
Sbjct: 7785 RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASC 7844

Query: 2998 SSTVYCTSKDNLIER 3012
            ++ ++       ++R
Sbjct: 7845 TTHLFVKEPATFVKR 7859



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 2504 EFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF 2563
            E E P F  +     +L  G+   ++  V   G   ++  W  +  E++ G  ++ T   
Sbjct: 8134 EHEVPPFFDLKPVSVDLALGESGTFKCHVT--GTAPIKITWAKDNREIRPGGNYKMTLVE 8191

Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590
               TL +  V   DAG Y C A N AG
Sbjct: 8192 NTATLTVLKVGKGDAGQYTCYASNIAG 8218



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDS 2179
            +L  G+   F+C V       + I W  + ++IR G  Y+ T       L +L     D+
Sbjct: 8149 DLALGESGTFKCHVT--GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDA 8206

Query: 2180 GTYMCKATNKLGE 2192
            G Y C A+N  G+
Sbjct: 8207 GQYTCYASNIAGK 8219



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 17/52 (32%), Positives = 28/52 (53%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            +KI W  + + +  G  +K+T      TL ++ V + D+G YTC A N  G+
Sbjct: 8168 IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGK 8219



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G N+ F   V+ +  P   + WF  +  L  G R   + + S   L++       SG YT
Sbjct: 8716 GTNVTFTSIVKGT--PPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYT 8773

Query: 2848 CKATNSKGSATTSGSL 2863
            C  +N  G A+ +  L
Sbjct: 8774 CIVSNEAGKASCTTHL 8789



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/66 (30%), Positives = 28/66 (42%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q +    P++ + WY     L   + +K+       TL    V   DSG Y CKA N  G
Sbjct: 8908 QCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVG 8967

Query: 2994 EAFTSS 2999
            E   S+
Sbjct: 8968 EVSAST 8973



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            + P F  + + ++  + G  V F+C +       + V W+K+G+P+      +       
Sbjct: 8982 LPPSFSRQLRDVQETV-GLPVVFDCAISG--SEPISVSWYKDGKPLKDSPNVQTSFLDNT 9038

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
              L+I       +G Y+C A N +G+   S RL
Sbjct: 9039 ATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 42/158 (26%), Positives = 68/158 (43%), Gaps = 11/158 (6%)

Query: 3510 MKVQGKRNIILESQLPKGMEGTIDKIAALEG-YSGTVDTLTPEAE---SGNPPEFTTTPS 3565
            +K QG+    +E ++ K      D  A  +G Y+   + L   AE      P +FT    
Sbjct: 9711 LKPQGRHKTEVEHKVHKLT--IADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQ 9768

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            ++++SE+ SA FEC    V+     V W+     L    +    ND     + I  V   
Sbjct: 9769 NIVVSEHQSATFECE---VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPD 9825

Query: 3626 DAGLYTCKA-TNRHGEATVSCKLQVKGRQGIILEPQLP 3662
            D G+Y+  A     GEA  + +L +  ++ I LE + P
Sbjct: 9826 DEGVYSVIARLEPRGEARSTAELYLTTKE-IKLELKPP 9862



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/165 (22%), Positives = 61/165 (36%), Gaps = 11/165 (6%)

Query: 395   VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMIT 453
             VK  +D+ V       F C +  +  P + WF    +I  + N K  +   GNH  L I 
Sbjct: 12236 VKPIRDQHVKPKGTAIFACDIA-KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIK 12294

Query: 454   NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
             N    D          K     +  +L + E+E     + ++    + + E E    +A 
Sbjct: 12295 NAMPEDIAEYAVEIEGKR----YPAKLTLGEREV----ELLKPIEDVTIYEKESASFDAE 12346

Query: 514   AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
                   P   W+  G  + P+P   I  +GG   L + + K   A
Sbjct: 12347 ISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLRKVKLDQA 12390



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 4/123 (3%)

Query: 1663  TSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRV 1722
             TS   ++ S+   +     E  L  ++Q++   K    +AQ +V+   P FT+ + D   
Sbjct: 12542 TSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTA 12601

Query: 1723  AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782
              E      +  +       + V+W ++G  I  S + +   D     L +K  + +D G 
Sbjct: 12602 VEKDEITLKCEV----SKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGE 12657

Query: 1783  YTC 1785
             Y C
Sbjct: 12658 YVC 12660



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 3/79 (3%)

Query: 635   PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
             PP +F  PL+  T  EG     E     V     K++W KNG  I  S ++  +      
Sbjct: 13210 PPVEFTKPLEDQTVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVR 13266

Query: 695   SLDMLSLNIQDSGEYTCRA 713
              L +     +D   YTC A
Sbjct: 13267 KLVIHDCTPEDIKTYTCDA 13285



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/98 (25%), Positives = 39/98 (39%), Gaps = 2/98 (2%)

Query: 766   TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
             T + P+    ++ L  L        E   T    P  ++ W K    +    RIT I N 
Sbjct: 14611 TQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRIT-IENV 14669

Query: 826   GYVS-LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                S + I+  +  D G+Y + AVN  G A +   + V
Sbjct: 14670 PKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 14707



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 1584  LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSC 1642
             ++ + +K G    F   +  V   T K  W  +   +K+   +T ET+NF  V L I +C
Sbjct: 18444 IEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 18500

Query: 1643  LPEDSGTYTCRAINALG 1659
             L  D+G Y     NA G
Sbjct: 18501 LRRDTGEYQITVSNAAG 18517



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/66 (28%), Positives = 28/66 (42%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P   + W K+G+ +    R+  I +   V L I      D G Y + A N  G A  +A 
Sbjct: 18863 PEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAI 18922

Query: 860   IRVAAR 865
             + V  R
Sbjct: 18923 VNVLDR 18928



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/64 (34%), Positives = 27/64 (42%)

Query: 3591  VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             + W   GK L+   RV  I D   V L+I    + D G Y   A N  G A  S  + V 
Sbjct: 18867 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVL 18926

Query: 3651  GRQG 3654
              R G
Sbjct: 18927 DRPG 18930



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             +    +K  +++K G     +A +   G     V W KDG  ++ +  I          L
Sbjct: 20223 DLSVAMKSLLTVKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTL 20280

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
              + SV   D+G YT  A N+ G  + +  L ++ K
Sbjct: 20281 ELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 20315



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
             V  G     D  V G+P P V+W  +   ++     K+ + +     L + +V   DSG 
Sbjct: 20234 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVNRKDSGD 20292

Query: 463   VTCVARNKSGETAFQCRLNVIEK 485
              T  A N SG  +   +L V++K
Sbjct: 20293 YTITAENSSGSKSATIKLKVLDK 20315



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 6/105 (5%)

Query: 383   IEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
             +EI E+ +AP F    + R    V  G   R    + GRP PEVTW  ++  +++  N  
Sbjct: 21692 VEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRAN-- 21749

Query: 440   ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
              + N      L+I      D+G       N +G+ +    + V++
Sbjct: 21750 -IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLD 21793



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/114 (19%), Positives = 56/114 (49%), Gaps = 5/114 (4%)

Query: 4692  DYKCVAYNSAGRVTVAAKLK--VTQPD--QADNLPALTPLRDIVVYE-GQPAQFKTQITS 4746
             +++ +A N+AG ++  ++    +T  D  +A  +      +D V+ + G+  + +  ++ 
Sbjct: 22355 EFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSG 22414

Query: 4747  KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +  PT++W ++G  +  T   ++     +  L+  ++   D+G +T  AT   G
Sbjct: 22415 RPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 22468



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 17/82 (20%), Positives = 35/82 (42%)

Query: 4732  VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             V  G+  +       +  P + W ++   + +T         NN++L I +   ED G +
Sbjct: 23086 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 23145

Query: 4792  TCRATTAAGQVETSAKLVVKSK 4813
               + T +AG+   +  ++V  K
Sbjct: 23146 VVKLTNSAGEAIETLNVIVLDK 23167



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/55 (36%), Positives = 24/55 (43%)

Query: 2803  PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSA 2857
             PT  + W  +N PL   TR  +    +   L I     ED G Y  K TNS G A
Sbjct: 23102 PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 23156



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 2/73 (2%)

Query: 2788  GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
             G ++  E  +     PT  I W  +  PL   TR   T      +L I  T+++D G Y 
Sbjct: 24171 GQDLKIEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYG 24228

Query: 2848  CKATNSKGSATTS 2860
                 N  G  T S
Sbjct: 24229 ITVANVVGQKTAS 24241



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 2/88 (2%)

Query: 1185  NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244
             N   +  G+++ +E  +  +G P   + W  +G  +   +R           L I     
Sbjct: 25246 NTYSIQAGEDLKIE--IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNK 25303

Query: 1245  ADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
              D G+YTV A N  G+A  +  V V+E+
Sbjct: 25304 DDFGKYTVTATNSAGTATENLSVIVLEK 25331



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 2/75 (2%)

Query: 3157  NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             N   ++ G+    E  V+    P+  I W  +G+P++ +TR+         VL I     
Sbjct: 25246 NTYSIQAGEDLKIEIPVIGRPRPN--ISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNK 25303

Query: 3217  HDSGEYVCRAYNKYG 3231
              D G+Y   A N  G
Sbjct: 25304 DDFGKYTVTATNSAG 25318



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 17/65 (26%), Positives = 29/65 (44%)

Query: 1738  GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
             G P+  V W ++G  ++ + R+         +L++K  + ED GTY     N  G     
Sbjct: 26347 GRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 26406

Query: 1798  STLFV 1802
              T+ V
Sbjct: 26407 ITIIV 26411



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 3/103 (2%)

Query: 3042  DDTGRPPEFTTV-FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
             DD   P     V F+D++ +  G++    A +   G    VI W  +G  IE   R   +
Sbjct: 26709 DDVEPPRVMMDVKFRDVIVVKAGEVLKINADI--AGRPLPVISWAKDGIEIEERARTEII 26766

Query: 3101  YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
                   +L +      D+G Y     N  G   ++V  + +DK
Sbjct: 26767 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 26809



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 4/86 (4%)

Query: 4627  EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
             E  K  IV  G +   +    G+P+P V W K D  ++   Y  +  T    +L I  A 
Sbjct: 27118 EMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENAN 27175

Query: 4687  PEDEGDYKCVAYN--SAGRVTVAAKL 4710
               D G Y     N  SA  +T+  K+
Sbjct: 27176 RNDSGKYTLTIQNVLSAASLTLVVKV 27201



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 6/70 (8%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ--TGDVSLLIKQIGPGDEGE 143
             G N K +  + G P P V+ +R   PL    K +MR+N +    ++++ +K+    D G 
Sbjct: 27418 GSNLKVDIPISGKPLPKVTLSRDGVPL----KATMRFNTEITAENLTINLKESVTADAGR 27473

Query: 144   YTCTARNQYG 153
             Y  TA N  G
Sbjct: 27474 YEITAANSSG 27483



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 918   QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
             Q++++ G   H E   +  G     + WLKDG P++ S  +        + L+IK+    
Sbjct: 28499 QVTVRIGHNVHLELPYK--GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKE 28556

Query: 978   DAGHYTCRAYNAIGQATTSANLTIVT 1003
               G YT    NA+     +  +T++T
Sbjct: 28557 HGGKYTVILDNAV--CRIAVPITVIT 28580



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/63 (31%), Positives = 27/63 (42%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P  RV W+KDG  I     +      G  SL +     +  G YTV A N  G A +   
Sbjct: 28913 PVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIK 28972

Query: 860   IRV 862
             ++V
Sbjct: 28973 VKV 28975



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            + + P F   +Q V  L EG +A FEA +     P+  V WF +G+ +           F
Sbjct: 2    TTQAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISF 58

Query: 3338 --GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              G   L I    + NSG Y   ATN  G+ ++ A L
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/123 (21%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            +++ ++ T  P FV R +S+  V +G  V  + ++  +    +K  ++++G  +     F
Sbjct: 94   ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDF 150

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEAGL 1552
            +   +    +L I +   EDSG Y+  A N VG    +  L  +   ++  + T+     
Sbjct: 151  QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVST 210

Query: 1553 EQI 1555
             QI
Sbjct: 211  AQI 213



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADT 1247
            + EG  +   C++   G P  ++ W+ +G+ +  G R++  +   G  +L I      D 
Sbjct: 1302 ILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDE 1359

Query: 1248 GEYTVRAVNHLGSA 1261
            G YT  A N  G+A
Sbjct: 1360 GIYTAFASNIKGNA 1373



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P  I Q   + K+ EG   Q +V++S      V W K+GQ +  S++  I+       L 
Sbjct: 2355 PIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLL 2413

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            + +  K D+G+Y+     P   + TSG ++V S
Sbjct: 2414 IEDMTKEDAGNYSFTI--PALGLSTSGRVSVYS 2444



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I +  P+   PL +     EG  +HL   +    +    V W+   + V    +FK   D
Sbjct: 4284 IKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQD 4338

Query: 1232 FGFVALDIIHATSAD-TGEYTVRAVNHLGSAHTSAIVRVIERS 1273
                 L I    + D  GEY   A+N  G   TSA + V++R+
Sbjct: 4339 QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 4381



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/115 (22%), Positives = 47/115 (40%), Gaps = 3/115 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F    K ++    G    F C V   G P +   W  +G   +        +     
Sbjct: 4477 PPTFLSRPK-SLTTFVGKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWKISDAENKH 4533

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
             L++  +  +D G Y+C+A+NK+G+    A++    K   + E +  Q    +K+
Sbjct: 4534 ILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKV 4588



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 6/114 (5%)

Query: 3959 LTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            + + +L  +DK   P F+ +++   S +  +    ECQ+    D  + V W  +G+ L  
Sbjct: 4560 ICQAELIIIDK---PHFIKELEPVQSAINKKV-HLECQVDE--DRKVTVTWSKDGQKLPP 4613

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
               +   ++     +       +DSG Y+C A+N  G     A +     P  V
Sbjct: 4614 GKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFV 4667



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 9/98 (9%)

Query: 1433 TDIIDESVTIK--PRFVTRPKSIE--NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488
            +D     + IK  P F+   K++E  +++ G +   +C++        ++ WFK+ + + 
Sbjct: 4745 SDSCSTEIVIKEPPSFI---KTLEPADIVRGTNALLQCEVSGT--GPFEISWFKDKKQIR 4799

Query: 1489 IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
               ++R       V L+I    + D G Y C   N VG
Sbjct: 4800 SSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVG 4837



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/113 (23%), Positives = 44/113 (38%), Gaps = 3/113 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  ++ D I +  G  V     V   G   + + W           ++      G  
Sbjct: 4850 PPTFVKKVDDLIALG-GQTVTLQAAVR--GSEPISVTWMKGQEVIREDGKIKMSFSNGVA 4906

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
             L I  +     G+YTC A N+ GS T+  ++       I+  ++L Q  +G+
Sbjct: 4907 VLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGD 4959



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 14/53 (26%), Positives = 29/53 (54%), Gaps = 1/53 (1%)

Query: 4110 PPVFVS-LPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            P  FV  L  +  +++G+  +  C+VTG P  ++ W  N   I   S++++++
Sbjct: 5225 PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSF 5277



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 2/82 (2%)

Query: 781  ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
            ++ +G  A  + + +   + T +  W+KDG+ +T  S+           L I+    +D+
Sbjct: 5516 DVTQGDPATLQVKFSGTKEITAK--WFKDGQELTLGSKYKISVTDTVSILKIISTEKKDS 5573

Query: 841  GSYTVRAVNKLGEAISTASIRV 862
            G YT    N +G +   A I V
Sbjct: 5574 GEYTFEVQNDVGRSSCKARINV 5595



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 13/58 (22%), Positives = 28/58 (48%)

Query: 2533 VPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +  G   +  +W+ +  E+    +++ +       L+I+ +   D+G Y C A N+AG
Sbjct: 5624 IVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 5681



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 2/76 (2%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            L  GQ    E Q+     P +++ WY +G  +    +  ++   G  T  +      +SG
Sbjct: 5800 LRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSG 5857

Query: 2983 IYTCKAYNKRGEAFTS 2998
             Y C+A N  G A  S
Sbjct: 5858 TYVCEARNDAGTASCS 5873



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/76 (25%), Positives = 28/76 (36%)

Query: 926  FAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCR 985
            ++  E   E  G     V WLK+ R + +S + T         L I      D G Y C 
Sbjct: 5896 YSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCI 5955

Query: 986  AYNAIGQATTSANLTI 1001
              N  G  + S  + +
Sbjct: 5956 VSNEGGSCSCSTRVAL 5971



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F+ +I++ T++++   T F+  +A  G P + + W  + + L   +     +   
Sbjct: 5972 KEPPSFIKKIENTTTVLKSSAT-FQSTVA--GSPPISITWLKDDQILDEDDNVYISFVDS 6028

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
               +    V    SG Y C+A N  G++   A +
Sbjct: 6029 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFL 6062



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/101 (22%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E + I  G P  +++W ++ V + +  +     +     LN+  V+   +G YTC   N+
Sbjct: 6275 EFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTND 6334

Query: 1791 LGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQ 1831
            +G    ++ L V        + +      KI +  DSSR +
Sbjct: 6335 VGSDSCTTMLLVTEPPKFVKKLE----ASKIVKAGDSSRLE 6371



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F++     + L   + V LE ++     P  ++ W+K+   L +  + K     
Sbjct: 6440 VKEPPVFSSFPPIVETLKNAE-VSLECELSGT--PPFEVVWYKDKRQLRSSKKYKIASKN 6496

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               ++ I ++   D G Y CKA N +G      ++K+++
Sbjct: 6497 FHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE 6535



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 3/83 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P+FTQ    P    +G     +  +   G P     W  +  +++   +F+ T      +
Sbjct: 7385 PVFTQK-PSPVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTS 7441

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
            L I ++ A+D G Y CKA N  G
Sbjct: 7442 LHILNLEASDVGEYHCKATNEVG 7464



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/65 (26%), Positives = 31/65 (47%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L  +W KDGR + A S+    F     +L I    + D G Y+    N++G++  +
Sbjct: 7597 GTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT 7656

Query: 997  ANLTI 1001
             ++ +
Sbjct: 7657 VSVHV 7661



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/71 (23%), Positives = 33/71 (46%)

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
            P  +V+W+   + L  G     S +     L++  V   +SG+Y+C   N+ G A  +  
Sbjct: 7788 PPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTH 7847

Query: 1934 LNVQSKESIIR 1944
            L V+   + ++
Sbjct: 7848 LFVKEPATFVK 7858



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/61 (27%), Positives = 29/61 (47%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  K++WF  ++ L  G     + +     L++      +SG Y+C  TN  GSA+ +  
Sbjct: 7788 PPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTH 7847

Query: 2863 L 2863
            L
Sbjct: 7848 L 7848



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F +   SV    G    F+  +   G   +KI W K+ + I     +         +
Sbjct: 8138 PPFFDLKPVSVDLALGESGTFKCHV--TGTAPIKITWAKDNREIRPGGNYKMTLVENTAT 8195

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +L +   D+G+YTC A +  G     A L V
Sbjct: 8196 LTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGV 8228



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/66 (28%), Positives = 29/66 (43%)

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
            + V WY + KPLK       +       L+I       +G Y+C A N +G A +S   I
Sbjct: 9013 ISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLI 9072

Query: 1669 VHSKKS 1674
            +   K+
Sbjct: 9073 LTEGKN 9078



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 2940 DPDLKIEWYFNGK--VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            DP   ++W   GK   L QG R  +        L++ D  + DSG+Y C A+N+ GE
Sbjct: 9407 DPIPNVKWT-KGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGE 9462



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 13/47 (27%), Positives = 24/47 (51%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            P +K EW +NG+ ++   R  +        L +  +  +D G+YTC+
Sbjct: 9698 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 9744



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 41/189 (21%), Positives = 79/189 (41%), Gaps = 15/189 (7%)

Query: 4226  RTETELEKTFEERQVLQRQGV---IDHRPEL-KPKVIKEPETEWQQSVKRKKNEEYYNKL 4281
             R E   +   EE++ +  + +   +  R E+ + +V  E E  + +  +      Y  + 
Sbjct: 10381 RAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEE 10440

Query: 4282  QELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKV 4341
             +E E E  + E  + E   +Y +  +K+        +++R E    +  EVTE R +KK+
Sbjct: 10441 REEEEEAEVTEYEVMEEPEEYVVE-EKL------HIISKRVEA---EPAEVTE-RQEKKI 10489

Query: 4342  TQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVV 4401
               KP+IP   E     K     K+   +K+V        K+   +  E   K   +++V 
Sbjct: 10490 VLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVP 10549

Query: 4402  EGPVKPSKP 4410
                +K  +P
Sbjct: 10550 PKVIKMEEP 10558



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 1445  RFVTRPKSI---ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
             +FV   K I   E+   G    FEC + P   S     W K+G  +    + R I D   
Sbjct: 12043 KFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKD 12099

Query: 1502  VALDIIDLIAEDSGIYTC 1519
               L IID+   D+G YTC
Sbjct: 12100 RKLHIIDVQLSDAGEYTC 12117



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 3422  FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
             FT PL + + + EG  A  E  ++     N KV+W+ NG  +    ++    D     L 
Sbjct: 13214 FTKPLED-QTVEEGATAVLECEVSRE---NAKVKWFKNGTEILKSKKYEIVADGRVRKLV 13269

Query: 3482  ISPTYPEDSGEYLCRA 3497
             I    PED   Y C A
Sbjct: 13270 IHDCTPEDIKTYTCDA 13285



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 771   QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSL 830
             +F+RPL DL +++E   A FE +L   S    +V+W+KDG  I    +   I       L
Sbjct: 13302 EFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGAVRIL 13357

Query: 831   NIMHLRAEDAGSYT 844
              I     +D   Y+
Sbjct: 13358 VINKCLLDDEAEYS 13371



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 29/56 (51%)

Query: 287   VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
             V  +G PRP  TW    + L   ++ ++ T   +  L +  +++SD G YTL  EN
Sbjct: 14343 VPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLEN 14398



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 2/93 (2%)

Query: 1977  KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
             KP       +  V EG  + +      V  PT  V W+ +G+ V+   R     D     
Sbjct: 15313 KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAH 15370

Query: 2037  LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             L++  +   D G Y     N +G A  + +VKV
Sbjct: 15371 LEVPKSVRADAGIYTITLENKLGSATASINVKV 15403



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 6/95 (6%)

Query: 69    PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
             PS  +  ++ +      G   +F   +RG P P   WT   + +    K    Y  +T +
Sbjct: 18435 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEI----KTDEHYTVETDN 18490

Query: 129   VS--LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              S  L IK     D GEY  T  N  G    +V++
Sbjct: 18491 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHL 18525



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 2/91 (2%)

Query: 912   KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTI 971
             K  + +QI+IK G     EA +   G      +W K    V  SS +          L I
Sbjct: 19828 KILMPEQITIKAGKKLRIEAHV--YGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 19885

Query: 972   KSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             K VT  D+G+Y+  A N+ G  T    + ++
Sbjct: 19886 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVM 19916



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 7/119 (5%)

Query: 4689  DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQ 4743
             +E  ++ +A NSAGR        V   +Q   LP L  LR I     +   G   + +  
Sbjct: 21958 EEYTFQVMAVNSAGRSAPRESRPVIVKEQT-MLPELD-LRGIYQKLVIAKAGDNIKVEIP 22015

Query: 4744  ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
             +  + KPT+ W +   ++ +T          + +L I      D+G +   A    G+V
Sbjct: 22016 VLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEV 22074



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 2651  YDKLV---EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             Y KLV    G ++ +E  V  R  P   + W K    L    R+          L+IN  
Sbjct: 21998 YQKLVIAKAGDNIKVEIPVLGRPKPT--VTWKKGDQILKQTQRVNFETTATSTILNINEC 22055

Query: 2708  RNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                DSG Y   A N++GE     +I++ D
Sbjct: 22056 VRSDSGPYPLTARNIVGEVGDVITIQVHD 22084



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 5/124 (4%)

Query: 4692  DYKCVAYNSAGRVTVAAKLK--VTQPDQAD--NLPALTPLRD-IVVYEGQPAQFKTQITS 4746
             +++ +A N+AG  +  ++    +T  D+ D   +      +D IVV+ G+  +    I  
Sbjct: 23437 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 23496

Query: 4747  KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
             K  PTIQW++    +  T   ++        L + +    D+G +  +A   AG+   + 
Sbjct: 23497 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 23556

Query: 4807  KLVV 4810
              + V
Sbjct: 23557 NVKV 23560



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/83 (21%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
             V  G+  + D  + G+P P + W   D+++ +    +I   +    +L + +    DSG 
Sbjct: 23482 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT-SLSVKDAVRVDSGN 23540

Query: 463   VTCVARNKSGETAFQCRLNVIEK 485
                 A+N +GE +    + V+++
Sbjct: 23541 YILKAKNVAGERSVTVNVKVLDR 23563



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1974  VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
             +V +P       +  V  G  + +E  ++    PT  + W  +G P++Q  R   T    
Sbjct: 24153 LVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLD 24210

Query: 2034  YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L I   + +D G Y     N VG+   T+S+++
Sbjct: 24211 LTTLSIKETHKDDGGQYGITVANVVGQ--KTASIEI 24244



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 3716  DCRVE-PV-GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT 3773
             D ++E P+ G P   I W  +G P    +R++  +      L I   +  D G+Y     
Sbjct: 24173 DLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVA 24232

Query: 3774  NKWGSATTTAKITCSAKRD 3792
             N  G  T + +I    K D
Sbjct: 24233 NVVGQKTASIEIVTLDKPD 24251



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/105 (21%), Positives = 45/105 (42%), Gaps = 4/105 (3%)

Query: 1301  VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
             + +D+T+  + +     ++I+  E     L+  +  +G     + W  +G+P+K   R  
Sbjct: 25231 IAKDLTIQPSLKLPFNTYSIQAGED----LKIEIPVIGRPRPNISWVKDGEPLKQTTRVN 25286

Query: 1361  PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                      L +     +D G YT  ATN  G A  + ++ V+ K
Sbjct: 25287 VEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 25331



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 5/94 (5%)

Query: 483   IEKEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539
             I KE+   P F    E   TL V+ G    +     G P P + W K    +       +
Sbjct: 27103 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYV 27160

Query: 540   HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
              T    ++L I  A  +D+  Y  T QNV  + +
Sbjct: 27161 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAAS 27194



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/85 (24%), Positives = 35/85 (41%)

Query: 494   VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
             +E    +  R G  V L A   G P P I W KD   +  N  + +      +++ I  A
Sbjct: 27803 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 27862

Query: 554   KASDAAWYQCTAQNVAGSTATRARL 578
                ++  Y+   +N  GS +   R+
Sbjct: 27863 DRLNSGCYELKLRNAMGSASATIRV 27887



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 1855  KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
             K   G S      I   P P   +EWY + K LQ+       N    A++ I      +S
Sbjct: 27810 KYRAGTSVKLRAGISGKPAPT--IEWYKDDKELQTNALVCVENTTDLASILIKDADRLNS 27867

Query: 1915  GEYTCKAINNLGQAVSSIRLNVQSK 1939
             G Y  K  N +G A ++IR+ +  K
Sbjct: 27868 GCYELKLRNAMGSASATIRVQILDK 27892



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/70 (25%), Positives = 30/70 (42%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  +  + F G P P + W ++   + +   + I    + S+L I QV   D+  +    
Sbjct: 28214 EDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTI 28273

Query: 4486  ENRGGTAKCS 4495
             EN  G  K S
Sbjct: 28274 ENGVGEPKSS 28283



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 6/109 (5%)

Query: 1701  SAQDEVIT-QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
             + ++ +IT +  +  +P   + V      H E  L   G PK  + WL++G+P++ S  +
Sbjct: 28480 TVKELIITPEVDLSDIPGAQVTVRIGHNVHLE--LPYKGKPKPSISWLKDGLPLKESEFV 28537

Query: 1760  TTMHDFGYVALNMKYVNPEDSGTYTC---RAINELGEAVTSSTLFVQSK 1805
                     + L++K    E  G YT     A+  +   +T  TL   SK
Sbjct: 28538 RFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSK 28586



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 2/61 (3%)

Query: 785   GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
             G N H E  L     P   + W KDG P+  S  +        ++L+I + + E  G YT
Sbjct: 28505 GHNVHLE--LPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 28562

Query: 845   V 845
             V
Sbjct: 28563 V 28563



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 8/119 (6%)

Query: 4700 SAGRVTVAAKLKVTQPDQADNL--PA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            S  R++   +L+ T   Q + L  P   L P+      EGQ A+F  ++  +  P   W 
Sbjct: 1433 SPARMSPGRRLEETDESQLERLYKPVFVLKPV-SFKCLEGQTARFDLKVVGRPMPETFWF 1491

Query: 4756 REGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +G  I      +++   +G  +++++  T   D+G +T  A   AG+   S  L V++
Sbjct: 1492 HDGQQIVNDYTHKVVIKEDGTQSLIIVPAT-PSDSGEWTVVAQNRAGRSSISVILTVEA 1549



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 774  RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIM 833
            +PL D   + E + A FE +   V++P  + EW +DG+ +  ++ I S  +     L I 
Sbjct: 2624 KPLTDQ-TVAESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIA 2679

Query: 834  HLRAEDAGSYTVR-AVNKLGEAISTASIRV 862
              + +D G YT + A +K    +   ++++
Sbjct: 2680 ATKLDDIGEYTYKVATSKTSAKLKVEAVKI 2709



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 2245 VTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDI 2304
            +T+      V E KTA FEC+V   + P++ ++   NG  ++ + +F I        L I
Sbjct: 2884 ITKTMKNIEVPETKTASFECEVSHFNVPSMWLK---NGVEIEMSEKFKIVVQGKLHQLII 2940

Query: 2305 QHCVPEDAGEYS 2316
             +   ED+ EY+
Sbjct: 2941 MNTSTEDSAEYT 2952



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/64 (29%), Positives = 31/64 (48%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P+++ +WF  G+++    +        I  L+IL     + GEY C A+N+ G  S  A 
Sbjct: 4410 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 4469

Query: 3372 LKCT 3375
            L  T
Sbjct: 4470 LTVT 4473



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/107 (23%), Positives = 47/107 (43%), Gaps = 3/107 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP F+ ++ D+  L  GQ+   +A  V   +P + V W    + +    + +     G+
Sbjct: 4849 EPPTFVKKVDDLIAL-GGQTVTLQAA-VRGSEP-ISVTWMKGQEVIREDGKIKMSFSNGV 4905

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQL 3386
             +L I        G+Y C+A N+ G  ++   L       +I  ++L
Sbjct: 4906 AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAEL 4952



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 16/56 (28%), Positives = 29/56 (51%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSAT 2858
            P LK +W+ + +PL +  +Y+ +   +   L        DSG YT + +N  GS++
Sbjct: 4971 PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSS 5026



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 2/106 (1%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F   ++         A F+A L   G   + V WL++   I   + +    +  
Sbjct: 5409 LREPPSFIKKIESTSSLRGGTAAFQATL--KGSLPITVTWLKDSDEITEDDNIRMTFENN 5466

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
              +L +  +  +  G Y C+A N+ G    S+ L V+  A++  E+
Sbjct: 5467 VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEA 5512



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 3/121 (2%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P FT  L  +++++ G     E  +     P + ++W+ + + + A  +++         
Sbjct: 5602 PSFTKKLKKMDSIK-GSFIDLEC-IVAGSHP-ISIQWFKDDQEISASEKYKFSFHDNTAF 5658

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            LEIS     DSG Y C A N  G    +  + V+     + + Q       T  ++ AL 
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALV 5718

Query: 3540 G 3540
            G
Sbjct: 5719 G 5719



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/103 (22%), Positives = 44/103 (42%), Gaps = 3/103 (2%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            ++  V++ P F   LK  + +V+   V LE +V     P  ++ W KN   + +  +   
Sbjct: 5874 IELKVKEPPTFIRELKPVE-VVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTL 5930

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            T    +  L I      D+G Y C  +N  G    +  + +++
Sbjct: 5931 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE 5973



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P+LKV+W  +GK++     +    +  +    I    +++SG+Y     N  G  S  A 
Sbjct: 6095 PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 6154

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L+       +LD  +P      L K+  +  S +
Sbjct: 6155 LR-------VLDQNIPPSFTKKLTKMDKVLGSSI 6181



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGMYHFD 4168
            P V V     +TV  GE     C+V G P+  V W  +G  + +  ++K + Y+ +    
Sbjct: 6630 PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLR 6689

Query: 4169 IPKTRQYDTG 4178
            I    + D G
Sbjct: 6690 ILSVERQDAG 6699



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 2/75 (2%)

Query: 2516 GPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVA 2575
            GP  +  G+    E +V   G P L  EWY +G  L    + + +      +L I SV  
Sbjct: 6638 GPMTVTVGETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVER 6695

Query: 2576 NDAGLYMCKAINRAG 2590
             DAG Y  +  N  G
Sbjct: 6696 QDAGTYTFQVQNNVG 6710



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 4/107 (3%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKD-GRPVEASSRITTFFNFG 965
            + P F   + D  ++  G      A +E  G   + V WLKD G  +  S      F   
Sbjct: 7476 EPPRFVKKLSDTSTLI-GDAVELRAIVE--GFQPISVVWLKDRGEVIRESENTRISFIDN 7532

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
               L + S    ++G Y C+  N  G    SA LT++    II + +
Sbjct: 7533 IATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPE 7579



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/55 (27%), Positives = 29/55 (52%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G   +   W+ +G E+  G + +++      TL+++ +  +D G+Y C A N AG
Sbjct: 7693 GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAG 7747



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F  +     +L   +    EC+L   G P   V W+ + + L    ++  + +  
Sbjct: 8323 KEPPIFRKKPHPIETLKGADV-HLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENF 8379

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
              +++   V   D GEY C+ATN  G D     I     P  V
Sbjct: 8380 LTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFV 8422



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/65 (26%), Positives = 32/65 (49%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L  +W KDG+ + + ++    F      L I +V   D+G Y+    N +G+ + +
Sbjct: 8538 GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCT 8597

Query: 997  ANLTI 1001
            A+L +
Sbjct: 8598 ASLQV 8602



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 4/107 (3%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            +V+E+K   P F+  L +++    G    F+  ++ ++   + V WY +GK LK     +
Sbjct: 8976 TVQEQK-LPPSFSRQLRDVQET-VGLPVVFDCAISGSEP--ISVSWYKDGKPLKDSPNVQ 9031

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
            T        L I  T    +G+Y C A N  G A ++A + +   +N
Sbjct: 9032 TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN 9078



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K PP F  ++    ++V  E+  FEC +   G   +KV W  + + +    ++   Y   
Sbjct: 9077 KNPPFFDIRLAPVDAVVG-ESADFECHVT--GTQPIKVSWAKDSREIRSGGKYQISYLEN 9133

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
               +    V   DSG+Y C A N  G D   A
Sbjct: 9134 SAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTA 9165



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/47 (38%), Positives = 24/47 (51%)

Query: 2538 PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCK 2584
            P+++ EW+ NG  LK   R +T  +     L I  V A D G Y CK
Sbjct: 9698 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 9744



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/52 (36%), Positives = 26/52 (50%)

Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL 1129
            EW+ NG+ +    R +T  +     L IA VRAED G YT    +    A+L
Sbjct: 9703 EWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAEL 9754



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 5/104 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   + NIV  E  +  FEC V  S D  + + W+     L    +Y   +D     + I
Sbjct: 9763 FTKRIQNIVVSEHQSATFECEV--SFDDAI-VTWYKGPTELTESQKYNFRNDGRCHYMTI 9819

Query: 2836 THTYEEDSGIYTCKA-TNSKGSATTSGSLRCTGDKNIYFDTQHP 2878
             +   +D G+Y+  A    +G A ++  L  T  K I  + + P
Sbjct: 9820 HNVTPDDEGVYSVIARLEPRGEARSTAELYLT-TKEIKLELKPP 9862



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 10/100 (10%)

Query: 3691  KPNPPRFTVEIKDNIDVPE---GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
             K  P +F  EIKD I       G    F+C V P    T    W  +G       +   +
Sbjct: 12038 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFI 12094

Query: 3748  NDFGFIALDIDYIYARDAGEYTC--RATNKWGSATTTAKI 3785
              D     L I  +   DAGEYTC  R  NK    T+TAK+
Sbjct: 12095 ADGKDRKLHIIDVQLSDAGEYTCVLRLGNK--EKTSTAKL 12132



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 910   EFKTPIKDQISIKE---GGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
             +F   IKD I  +    G  A FE  + P   ST    W+KDG  +  S +     +   
Sbjct: 12043 KFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKD 12099

Query: 967   VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
               L I  V + DAG YTC       + T++A L +
Sbjct: 12100 RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV 12134



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%)

Query: 1058  GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
             G SA FE  V P + +T    W  +G  I  + + +   D     L I  V+  D+G YT
Sbjct: 12060 GSSAIFECLVSPSTAITT---WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 12116

Query: 1118  VVARNAAGEAQLSASMTVE 1136
              V R    E   +A + VE
Sbjct: 12117 CVLRLGNKEKTSTAKLVVE 12135



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 3/81 (3%)

Query: 2776  FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
             F   L +   +EG     EC V  SR+   K++WF N   +    +Y+   D     L I
Sbjct: 13214 FTKPLEDQTVEEGATAVLECEV--SRE-NAKVKWFKNGTEILKSKKYEIVADGRVRKLVI 13270

Query: 2836  THTYEEDSGIYTCKATNSKGS 2856
                  ED   YTC A + K S
Sbjct: 13271 HDCTPEDIKTYTCDAKDFKTS 13291



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 16/135 (11%)

Query: 1824  LEDSSRYQ-----RREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMR 1877
             LED+  Y       R D +V V++ A  FI++     ++ EG+ A + C I     P   
Sbjct: 13453 LEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQN-LEILEGEKAEFVCSISKESFP--- 13508

Query: 1878  VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY-----TCKAINNLGQAVSSI 1932
             V+W  + K L+SG +Y    D     L +     +D G Y       +A  +L   +  +
Sbjct: 13509 VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHL-TVIEKL 13567

Query: 1933  RLNVQSKESIIRDSQ 1947
             R+ V  K++ +++ Q
Sbjct: 13568 RIVVPLKDTRVKEQQ 13582



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 16/180 (8%)

Query: 3058  VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
             ++I EG+ A +  S+     +S  ++W  + KT+E+  +   +      VL +      D
Sbjct: 13488 LEILEGEKAEFVCSI---SKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQD 13544

Query: 3118  SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
              GTY        G A  +  L  ++K +   P   T +      K+ Q   F C    V+
Sbjct: 13545 MGTYVVMV----GAARAAAHLTVIEKLRIVVPLKDTRV------KEQQEVVFNC---EVN 13591

Query: 3178  DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
                 K +W+ N + +  S++   +       L I      D   Y     N  GE+   A
Sbjct: 13592 TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSA 13651



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 52/267 (19%), Positives = 101/267 (37%), Gaps = 22/267 (8%)

Query: 4371  EVVGDKEITRKITSTETTEIEHKAQTQERV-VEGPVKPSKPPIFTKKMQPCRVFEHEQAR 4429
             +V+   E+  ++ +     + H ++  E + +E P  P  PP+        R  +H    
Sbjct: 15174 DVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIA 15231

Query: 4430  FEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVFVEDSAVFAAV-AEN 4487
             ++        P+I ++ E  P+      ++++   K +   + +  V D      V A N
Sbjct: 15232 WKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVN 15291

Query: 4488  RGGTAK---CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
               G ++    S N+V ++   +       P+  L   ++ V  G+ + +           
Sbjct: 15292 AIGVSEPSEISENVVAKDPDCK-------PTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 15344

Query: 4545  VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VV 4603
             V W K+GK+V+   R  +  +  +  L + ++   D+G Y     N  G A       V+
Sbjct: 15345 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 15404

Query: 4604  SLPA------TKDKPKPQTKAANAPPE 4624
              LP         D  K   K    PPE
Sbjct: 15405 GLPGPCKDIKASDITKSSCKLTWEPPE 15431



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 2923  LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
             ++EG+ L +   V  +  P   + W+ +GK ++   R  + +D     L++      D+G
Sbjct: 15325 VIEGEKLSIP--VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAG 15382

Query: 2983  IYTCKAYNKRGEAFTSSTV 3001
             IYT    NK G A  S  V
Sbjct: 15383 IYTITLENKLGSATASINV 15401



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/61 (31%), Positives = 28/61 (45%)

Query: 3454  VEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             V W+ +GK +KA  R     D     LE+  +   D+G Y     N  G A  + ++KV 
Sbjct: 15345 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 15404

Query: 3514  G 3514
             G
Sbjct: 15405 G 15405



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/71 (23%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 232   REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
             +E  FR    +   G S+   +T   +++ P+  PK+  +  + +++ G +      +SG
Sbjct: 15575 KEYQFRVR-AENAAGISEPSRATPPTKAVDPIDAPKVILRT-SLEVKRGDEIALDASISG 15632

Query: 292   NPRPRVTWFKN 302
             +P P +TW K+
Sbjct: 15633 SPYPTITWIKD 15643



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/93 (25%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 3423  TVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI 3482
             +V + ++  ++ G N   +A  T    P   V W  +G  LK     +         LE+
Sbjct: 20225 SVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 20282

Query: 3483  SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
                  +DSG+Y   A N+ G    T  +KV  K
Sbjct: 20283 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 20315



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/91 (24%), Positives = 38/91 (41%), Gaps = 2/91 (2%)

Query: 2916  PIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVD 2975
             P  + + +  GQ L +E  +  +  P   I W  +G  L+Q +R  +T      TL + +
Sbjct: 24161 PAFSSYSVQVGQDLKIEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLDLTTLSIKE 24218

Query: 2976  VYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
              ++ D G Y     N  G+   S  +    K
Sbjct: 24219 THKDDGGQYGITVANVVGQKTASIEIVTLDK 24249



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 637   PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
             P   +P  + +   G  +  E  I  +G P   I W+K+G+ ++ ++R           L
Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIE--IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVL 25296

Query: 697   DMLSLNIQDSGEYTCRAVSATGVA 720
              +   N  D G+YT  A ++ G A
Sbjct: 25297 HIKEGNKDDFGKYTVTATNSAGTA 25320



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/77 (27%), Positives = 32/77 (41%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P   V W KDG+ +  ++R+    +    SL+I     ED G+Y +   N  G      +
Sbjct: 26349 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPIT 26408

Query: 860   IRVAARSTVTADLGIPE 876
             I V  R      + I E
Sbjct: 26409 IIVLDRPGPPGPIRIDE 26425



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/62 (24%), Positives = 30/62 (48%)

Query: 943   VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             V W KDG+ ++ ++R+    +    +L+IK  +  D G Y     N+ G  T    + ++
Sbjct: 26353 VNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVL 26412

Query: 1003  TK 1004
              +
Sbjct: 26413 DR 26414



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
             G N   E   +G P P +SW +   PL E     +R+++    ++L IK       G+YT
Sbjct: 28505 GHNVHLELPYKGKPKPSISWLKDGLPLKESE--FVRFSKTENKITLSIKNAKKEHGGKYT 28562

Query: 146   CTARNQYGEAICSVYI 161
                 N    A+C + +
Sbjct: 28563 VILDN----AVCRIAV 28574



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 1832  RREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH 1891
             R E+V   V   P +   L     +  G+S   +  ++  P P  RV W+ +G  ++   
Sbjct: 28877 RDENVPPIVEFGPEYFDGLI----IKSGESLRIKALVQGRPVP--RVTWFKDGVEIEKRM 28930

Query: 1892  RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
                 ++  G  +L +     +  G YT +A N  G A + I++ VQ
Sbjct: 28931 NMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28976



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/68 (29%), Positives = 30/68 (44%)

Query: 2007  PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
             P  RV W+ +G  +++    + T   G  +L +  A  +  G Y  +A NA G A     
Sbjct: 28913 PVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIK 28972

Query: 2067  VKVDAKSG 2074
             VKV    G
Sbjct: 28973 VKVQDTPG 28980



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/70 (25%), Positives = 28/70 (40%)

Query: 4431  EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
             +V   G P P + W  E   +K +    I T   ++ L ++     DS  +    EN  G
Sbjct: 29595 DVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 29654

Query: 4491  TAKCSANLVV 4500
                 S  +VV
Sbjct: 29655 VKTFSVTVVV 29664


>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
          Length = 26926

 Score =  294 bits (722), Expect = 4e-78
 Identities = 268/1028 (26%), Positives = 456/1028 (44%), Gaps = 98/1028 (9%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY---RTVYDMGF 3886
            P F+ ++K+  ++E  G + E +V    +P   I W +N  ++   H+Y   R     G 
Sbjct: 1510 PMFVEKLKNVNIKE--GSQLEMKVRATGNPNPDIVWLKNSDIIVP-HKYPKIRIEGTKGE 1566

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK---KLPDIILQNQVPRGMKRSE-- 3941
             +L I    ++DS  Y   A+N  G D T+  ++ +     P+   +  +PRG  R++  
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 3942 ALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVG 4001
            A  ++E    +Y  E +  E DLYD +K+Q P F  ++ S   L       FEC+L P+G
Sbjct: 1627 AAPELEPLHLRYGQEQW-EEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPIG 1684

Query: 4002 DPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
            DP M VEW  +GKPL   NR   I +FGY ++++G  Y  DSG   CRATN YG D T A
Sbjct: 1685 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1744

Query: 4062 VIKTTGKPGIVYDSQLPKHMKSIEKIREMEA-SWQVTPEQVVEESKARCPPVFVSLPDAV 4120
             +    +  +V +SQLP+  K +++I E+E  + +     V  + K +  P  V  P+ V
Sbjct: 1745 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1804

Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGKI 4180
             V EGE ARF CRVTG+P+P+V W LNG  I    R+++ YDG+++ DI   + YDTG++
Sbjct: 1805 RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEV 1864

Query: 4181 EVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYD-ETTQYQRTETELEK------ 4233
            +V              L++  R +D+R VL+ AP P  +    +  + + E++K      
Sbjct: 1865 KVTAENPEGVIEHKVKLEIQQR-EDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVD 1923

Query: 4234 TFEERQV--LQRQGVIDHRP------ELKPKVIKEPETEWQQSV------KRKKNEEYYN 4279
            T E ++V  L+R   I H        EL+ K  +  E  + +++       RKK+E Y  
Sbjct: 1924 TTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEE 1983

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQT---EEVTEQR 4336
             L++ ++E +     L E   +      K+T  T      +    +++     E +  Q 
Sbjct: 1984 LLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIE-LSPSMEAPKIFERIQSQT 2042

Query: 4337 VQKKVTQKPRI-----PDPSESTVHGKEVHVAKQKQTQKEVVGDKE---ITRKITSTETT 4388
            V +      R+     PDP E   +   V + +  +       D     + R +T+ ++ 
Sbjct: 2043 VGQGSDAHFRVRVVGKPDP-ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSA 2101

Query: 4389 EIEHKAQTQERVVEGP----VKPSKPPIFTKKMQPCRVFEHE-QARFEVEFDGEPLPLIK 4443
             I  KA              V+  +   FT+++Q     E +  A FE E   EP   +K
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECE-TSEPFVKVK 2160

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            WY++   +     +++H+      L I  +   D+  ++ V        K +A L+VE  
Sbjct: 2161 WYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE-DENVKTTAKLIVE-- 2217

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                 G +V   F    Q++ V       L+  +   + I+  W  N  +++ + +  I 
Sbjct: 2218 -----GAVV--EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTIT 2269

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623
               G   L + +   +D G+Y  V      +  C           K K KP+      P 
Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTC-----------KLKMKPR------PI 2310

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
             I++ L D+ V EG  ++   K+  + +  V W K  + ++PS    +      + L I 
Sbjct: 2311 AILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIE 2369

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
            +   ED G+Y       A  ++ + ++ V   D       +TPL+D+ V EG  A  + +
Sbjct: 2370 DMTKEDAGNYSFTI--PALGLSTSGRVSVYSVD------VITPLKDVNVIEGTKAVLECK 2421

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            ++     +++W      I      Q I +G    L+I  T+  D G +        G+VE
Sbjct: 2422 VSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY----KLIVGRVE 2477

Query: 4804 TSAKLVVK 4811
            T+  L V+
Sbjct: 2478 TNCNLSVE 2485



 Score =  257 bits (630), Expect = 6e-67
 Identities = 163/511 (31%), Positives = 249/511 (48%), Gaps = 14/511 (2%)

Query: 377  RETEERIEIS-EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            R  EE  E   E+   P FV         EG+  RFD +V GRP PE  WF + +QI +D
Sbjct: 1395 RRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVND 1454

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
            Y HK+++ E G  +L+I   T SDSG  T VA+N++G ++    L V   E  V P FVE
Sbjct: 1455 YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514

Query: 496  RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN--PELRIHTDGGASTLDIPRA 553
            +   +N++EG  + +  RA G P P I W K+   I+P+  P++RI    G + L I   
Sbjct: 1515 KLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDST 1574

Query: 554  KASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXX 613
             + D+AWY  TA N AG   TR ++           +++L +PR T              
Sbjct: 1575 VSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPL 1634

Query: 614  YLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            +LR+ +         ++++    P F   L S+     G  HFE R+ P+GDPTM +EWL
Sbjct: 1635 HLRYGQEQWEEGDLYDKEK-QQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWL 1693

Query: 674  KNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             +G+ +EA++R   I  FGY SLD      +DSG  TCRA +  G   T A L V    +
Sbjct: 1694 HDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKS 1753

Query: 734  IERTSQHPETLQYIQQLEDYSKYQHQESI-----EEQTSQRPQFIRPLQDLGELQEGRNA 788
            +   SQ PE  + +Q++E+  +  H+ ++     +++  Q+P  +   + +  L EG  A
Sbjct: 1754 LVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVL-EGETA 1812

Query: 789  HFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAV 848
             F  ++T    P  +V WY +G+ I  S R    ++ G   L+I+  ++ D G   V A 
Sbjct: 1813 RFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAE 1869

Query: 849  NKLGEAISTASIRVAARSTVTADL-GIPEQR 878
            N  G       + +  R    + L   PE R
Sbjct: 1870 NPEGVIEHKVKLEIQQREDFRSVLRRAPEPR 1900



 Score =  188 bits (457), Expect = 6e-46
 Identities = 221/822 (26%), Positives = 347/822 (42%), Gaps = 106/822 (12%)

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTN-KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
            R  +  E +++   KP F+  LK  + K +EGQ+A F+ +V  +  +  T  W+ +G+QI
Sbjct: 1396 RLEETDESQLERLYKPVFV--LKPVSFKCLEGQTARFDLKVVGRP-MPETF-WFHDGQQI 1451

Query: 1087 TS--ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTS 1144
             +   +++    D G  +L I      DSG +TVVA+N AG + +S  +TVE        
Sbjct: 1452 VNDYTHKVVIKED-GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA------- 1503

Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPM 1204
                        +E    V+PM+    + K K V ++         EG  +  E ++   
Sbjct: 1504 ------------VEHQ--VKPMF----VEKLKNVNIK---------EGSQL--EMKVRAT 1534

Query: 1205 GDPTMRVEWFHNGRSVTVGS--RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAH 1262
            G+P   + W  N   +      + +     G  AL I    S D+  YT  A+N  G   
Sbjct: 1535 GNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDT 1594

Query: 1263 TSAIVRV--------IERSDIV---TDTQNEQAIEQIQLLEDAARRTKQVREDI---TVM 1308
            T   V V         ER  I+   T    E A  +++ L     + +    D+      
Sbjct: 1595 TRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQ 1654

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P F + L ++        H ECRL P+GD TM VEW  +GKP++  +R R   EF Y 
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1714

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            +LD    Y  DSG+ TC+ATN+ G   TS  L V  +K L+ ESQ P G + +Q +E+  
Sbjct: 1715 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELE 1774

Query: 1429 RYKKTDII-----DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN 1483
            R      +     D+    KP  V  P+ +  V+EG+   F C++        KV W+ N
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLN 1831

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            GQ +    RFR  +D G   LDI+D  + D+G     A N  G  E   +L  +   D  
Sbjct: 1832 GQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF- 1889

Query: 1544 RSTQNEA--GLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKN-VEIKEGQRAHFERR 1600
            RS    A     +  V E          VD      P+ TT  K  V++K  +R   E+ 
Sbjct: 1890 RSVLRRAPEPRPEFHVHEPGKLQFEVQKVDR-----PVDTTETKEVVKLKRAERITHEK- 1943

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNF-GFVALDIMSCLPEDSGTYTCRAINALG 1659
             +P     L+ ++           R TE   +    A+++ S   ++S     R      
Sbjct: 1944 -VPEESEELRSKF----------KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-- 1990

Query: 1660 EAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKD 1719
                    ++H  K   L  + + AL    ++     ++    +     +AP     ++ 
Sbjct: 1991 -------ELLHWTKE--LTEEEKKALAEEGKI-TIPTFKPDKIELSPSMEAPKIFERIQS 2040

Query: 1720 IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPE 1778
              V +   AHF  R+  VG P    EW +NGV IE S+R+        V  L ++ V  E
Sbjct: 2041 QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2098

Query: 1779 DSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
            DS +   +AIN  GE  + + L VQ+K  +    + +  + K
Sbjct: 2099 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2140



 Score =  187 bits (455), Expect = 1e-45
 Identities = 178/649 (27%), Positives = 283/649 (43%), Gaps = 60/649 (9%)

Query: 3293 KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT-FHDFGIVILDILYCYEEN 3351
            +++EG    F  ++     P  K+ W+ +GK++ HG RY+  F   G   L I     E+
Sbjct: 1255 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312

Query: 3352 SGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTS 3411
             G Y   A+N       K N  C+ K  L ++   P G       + TLE   V R  + 
Sbjct: 1313 EGIYTAFASN------IKGNAICSGK--LYVEPAAPLGAP---TYIPTLEP--VSRIRSL 1359

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTP------TDDPNL----KVEWYWNGK 3461
                  ++P+   P + +   R        AR++P      TD+  L    K  +     
Sbjct: 1360 SPRSVSRSPIRMSP-ARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV 1418

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            S K         D   V   +  T+    G+ +    N+Y   V    +K  G +++I+ 
Sbjct: 1419 SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV---NDYTHKVV---IKEDGTQSLIIV 1472

Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEA-ESGNPPEFTTTPSDLILSENSSAHFECR 3580
               P              G S     LT EA E    P F     ++ + E S    + R
Sbjct: 1473 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVR 1532

Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGS--RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
                 + +  + W  N   ++     +++     G   L+I     +D+  YT  A N+ 
Sbjct: 1533 A--TGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1590

Query: 3639 GEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE----ETLHKR------EEITIE 3688
            G  T  CK+ V+  +    EP+       GT   +++     E LH R      EE  + 
Sbjct: 1591 GRDTTRCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649

Query: 3689 D-EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            D EK   P F  ++  ++ +   GP HF+CR+ P+GDPTM ++W H+G+P    +R+  +
Sbjct: 1650 DKEKQQKPFFKKKLT-SLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMI 1708

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSG-E 3806
            N+FG+ +LD    Y+RD+G  TCRATNK+G+  T+A +    ++ +V ESQLP+G  G +
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQ 1768

Query: 3807 KIKELER----GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            +I+ELER    G ++    ++      P  +   +   V E E  RF CRV     PK  
Sbjct: 1769 RIEELERMAHEGALTGVTTDQK-EKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPK-- 1825

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            + WY NG+L+    R+R  YD G   LDI+   + D+GE    A N  G
Sbjct: 1826 VNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1873



 Score =  174 bits (424), Expect = 6e-42
 Identities = 156/534 (29%), Positives = 234/534 (43%), Gaps = 64/534 (11%)

Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488
            R ++TD        KP FV +P S +  +EGQ   F+ K+  V     +  WF +GQ + 
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFK-CLEGQTARFDLKV--VGRPMPETFWFHDGQQIV 1452

Query: 1489 IGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
              +  +  I + G  +L I+     DSG +T  A                         Q
Sbjct: 1453 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVA-------------------------Q 1487

Query: 1548 NEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEGQRAHFERRLIPVSD 1606
            N AG   I V+           V+ V  Q  P+    LKNV IKEG +   E ++    +
Sbjct: 1488 NRAGRSSISVILT---------VEAVEHQVKPMFVEKLKNVNIKEGSQ--LEMKVRATGN 1536

Query: 1607 ATLKVEWYHNNKPLKSGS--RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                + W  N+  +      +       G  AL I S + +DS  YT  AIN  G   T 
Sbjct: 1537 PNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1596

Query: 1665 GIAIVH--------SKKSIYLESQH---EGALPRLNQLE---DTSKYQRHSAQDEVITQA 1710
                V          +K I     +   E A P L  L       +++     D+   Q 
Sbjct: 1597 CKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQK 1656

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +  +R+     AHFE RL P+GDP + VEWL +G P+EA+NRL  +++FGY +L
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1716

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
            +       DSG  TCRA N+ G   TS+TL V+ + SL  ESQ     + +Q++E+  R 
Sbjct: 1717 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1776

Query: 1831 QRREDVE-VAVNQAPR---FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                 +  V  +Q  +    I     P ++ EG++A + CR+  YP P  +V WY NG++
Sbjct: 1777 AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQL 1834

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++   R+R   D G   LDI+     D+GE    A N  G     ++L +Q +E
Sbjct: 1835 IRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1887



 Score =  165 bits (402), Expect = 3e-39
 Identities = 136/477 (28%), Positives = 216/477 (45%), Gaps = 33/477 (6%)

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            EGQ A ++  ++  G       WF++G+ I  + +H++  +   G   L I+    +DSG
Sbjct: 1424 EGQTARFDLKVV--GRPMPETFWFHDGQQIVNDYTHKV-VIKEDGTQSLIIVPATPSDSG 1480

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             ++  A N+ G++ ISV L         KP F   ++N+  +K+G  +  E  V    +P
Sbjct: 1481 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNV-NIKEG--SQLEMKVRATGNP 1537

Query: 3180 DMKIEWYHNGQ---PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
            +  I W  N     P ++  +I+     G   L I  T + DS  Y   A NK G D TR
Sbjct: 1538 NPDIVWLKNSDIIVPHKY-PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1596

Query: 3237 ATINC---YGKGGVYLESLQPDSLAKIRELES-------LQGAQQQTPSTPSAEPPK--- 3283
              +N    + +     + + P    + +E+ +       L+  Q+Q       +  K   
Sbjct: 1597 CKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQK 1656

Query: 3284 -FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
             F  +     +L     AHFE RL P+ DP + VEW ++GK L   +R R  ++FG   L
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1716

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG--GLEKLQTL 3400
            D    Y  +SG   C ATNK G D T A L    +++L+ +SQLP G +G   +E+L+ +
Sbjct: 1717 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1776

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
                     T+ ++EK K  +   P      + EGE A F  R+T    P  KV WY NG
Sbjct: 1777 AHEGALTGVTTDQKEKQKPDIVLYP--EPVRVLEGETARFRCRVTGYPQP--KVNWYLNG 1832

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
            + ++   RFR   D G   L+I      D+GE    A N  G       +++Q + +
Sbjct: 1833 QLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888



 Score =  162 bits (393), Expect = 3e-38
 Identities = 166/643 (25%), Positives = 270/643 (41%), Gaps = 50/643 (7%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSY--VS 2832
            +F+  L N+  KEG  +  E  V  + +P   I W  N+  +      K   + +    +
Sbjct: 1511 MFVEKLKNVNIKEGSQL--EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1568

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLE------- 2885
            L I  T  +DS  YT  A N  G  TT    RC  +  + F    P+ K  +        
Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTT----RCKVNVEVEFAEPEPERKLIIPRGTYRAK 1624

Query: 2886 --AVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKN 2939
              A  + E   L  G+        Y K +   P   +     +L      H E ++ P  
Sbjct: 1625 EIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIG 1684

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            DP + +EW  +GK LE  +R ++ ++FG+ +LD    Y RDSGI TC+A NK G   TS+
Sbjct: 1685 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1744

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKE--PGQQPDDDTGRPPEFTTVFKDI 3057
            T+    + +L+E +Q P+G +GL++I+ LE    +    G   D    + P+   ++ + 
Sbjct: 1745 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEP 1803

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V + EG+ A +   +  TG     + W+ NG+ I  S R R  Y  G+  L+I+  K+ D
Sbjct: 1804 VRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYD 1860

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKS-------KGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            +G     A N  G  E  VKLE   +        +  +PR   H+     L+      FE
Sbjct: 1861 TGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQ------FE 1914

Query: 3171 CTVV--PVDDPDMK-IEWYHNGQPMRHSTRIKTVSDFGFVV---LDIAYTQNHDSGEYVC 3224
               V  PVD  + K +      + + H    +   +         +  Y +   + E   
Sbjct: 1915 VQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKS 1974

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            R  ++  E+  R T +        L   +  +LA+  ++        +   +PS E PK 
Sbjct: 1975 RKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKI 2034

Query: 3285 ITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR-YRTFHDFGIVILD 3343
              +IQ  T + +G  AHF  R+V   DP+   EW+ NG K+    R Y  + +  +  L 
Sbjct: 2035 FERIQSQT-VGQGSDAHFRVRVVGKPDPE--CEWYKNGVKIERSDRIYWYWPEDNVCELV 2091

Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQL 3386
            I     E+S      A N  G  S+ A L   +K+ +    +L
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQEL 2134



 Score =  157 bits (380), Expect = 1e-36
 Identities = 119/421 (28%), Positives = 194/421 (46%), Gaps = 33/421 (7%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV--QQGHRFKTTYDFGY 2034
            KP F + +KN  + EG  + ++   T   +P   + W  N   +   +  + +     G 
Sbjct: 1509 KPMFVEKLKNVNIKEGSQLEMKVRAT--GNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE 1566

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG------LYLDTLDEQRLKKI 2088
             AL I    ++D+  Y   A N  G   T   V V+ +          +      R K+I
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 2089 Q--ELE----KYERPK----PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPIND 2138
               ELE    +Y + +     + +++  Q+P F   LTSL  LK    AHFECR+ PI D
Sbjct: 1627 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLR-LKRFGPAHFECRLTPIGD 1685

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P + ++W H+G+ + A +R R  ++FGY +LD    Y+ DSG   C+ATNK G    + T
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745

Query: 2199 LKVAGHRNIILDTQHP---NGLEKIRQLEAQGHS---TRIEVEEPKISPPRFVTELRGTT 2252
            L V   ++++ ++Q P    GL++I +LE   H    T +  ++ +   P  V       
Sbjct: 1746 LIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVL-YPEPV 1804

Query: 2253 HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDA 2312
             V EG+TA F C+V     P  ++ +Y NG+ ++ + RF + +D G   LDI  C   D 
Sbjct: 1805 RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1861

Query: 2313 GEYSVKAINALGHCTSAISMTVTAKGSIISESQR-PEGLEKIRELESAE-PFKRPEIPEP 2370
            GE  V A N  G     + + +  +    S  +R PE   +    E  +  F+  ++  P
Sbjct: 1862 GEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRP 1921

Query: 2371 V 2371
            V
Sbjct: 1922 V 1922



 Score =  153 bits (370), Expect = 2e-35
 Identities = 172/672 (25%), Positives = 280/672 (41%), Gaps = 59/672 (8%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASS-- 817
            E++E Q   +P F+  L+++  ++EG  +  E ++    +P   + W K+   I      
Sbjct: 1502 EAVEHQV--KPMFVEKLKNVN-IKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYP 1556

Query: 818  RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA---ARSTVTADLGI 874
            +I      G  +L I    ++D+  YT  A+NK G   +   + V    A       L I
Sbjct: 1557 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1616

Query: 875  PE---QRRYI---EKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
            P    + + I   E                     E  QKP FK  +   + +K  G AH
Sbjct: 1617 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAH 1675

Query: 929  FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
            FE RL PIGD T+ VEWL DG+P+EA++R+     FGY +L        D+G  TCRA N
Sbjct: 1676 FECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1735

Query: 989  AIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKR-----TEEEVKITQKP 1043
              G   TSA L +  +K ++ ESQ P G + +Q +E+  R +          + K  QKP
Sbjct: 1736 KYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKP 1795

Query: 1044 RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVAL 1103
              +       +++EG++A F  RV         V WY NG+ I  + R +  +D G   L
Sbjct: 1796 DIV-LYPEPVRVLEGETARFRCRVTGYPQ--PKVNWYLNGQLIRKSKRFRVRYD-GIHYL 1851

Query: 1104 DIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFV 1163
            DI   ++ D+G   V A N  G  +    + ++ R   D  S+ R   E           
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE--DFRSVLRRAPEP---------- 1899

Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223
             P + + E  K +   VQ +  P   +E K +    R E +    +  E      S  + 
Sbjct: 1900 RPEFHVHEPGKLQ-FEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE------SEELR 1952

Query: 1224 SRFKTYYDFGFV-ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
            S+FK   + G+  A+  +   S    E     +             ++  +  +T+ + +
Sbjct: 1953 SKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-------ELLHWTKELTEEEKK 2005

Query: 1283 QAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTM 1342
               E+ ++     +  K   E    M+AP+    + +    +G++ H   R++ VG    
Sbjct: 2006 ALAEEGKITIPTFKPDK--IELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRVVGKPDP 2061

Query: 1343 RVEWFCNGKPIKTGHRFRPAYEFDYVA-LDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
              EW+ NG  I+   R    +  D V  L +  V  EDS     +A N  GE  +S A  
Sbjct: 2062 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE-TSSHAFL 2120

Query: 1402 VIAKKDLILESQ 1413
            ++  K LI  +Q
Sbjct: 2121 LVQAKQLITFTQ 2132



 Score =  152 bits (368), Expect = 3e-35
 Identities = 167/695 (24%), Positives = 296/695 (42%), Gaps = 69/695 (9%)

Query: 1939 KESIIRDSQH---ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPV 1995
            +E +I++ ++   ++ LE++  LE+D   K AV        +  F   IKN  + EG  V
Sbjct: 1205 EERLIKEIEYRIIKTTLEEL--LEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGV 1262

Query: 1996 HLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCKA 2054
                 ++    P  ++ WY +G+ ++ G R++  +   G  +L I     ED G Y   A
Sbjct: 1263 TFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA 1320

Query: 2055 TNAVGEAVTTSSVKVDAKSGL----YLDTLDEQRLKKIQELEKYERPK-PIEEEQPGQRP 2109
            +N  G A+ +  + V+  + L    Y+ TL+   + +I+ L      + PI        P
Sbjct: 1321 SNIKGNAICSGKLYVEPAAPLGAPTYIPTLEP--VSRIRSLSPRSVSRSPIRMSPARMSP 1378

Query: 2110 VFLT-ALTSLENLKEGDRAHF--ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
              ++ A  S   +  G R     E ++E +  P   +       K   G   R   D   
Sbjct: 1379 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV--SFKCLEGQTAR--FDLKV 1434

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLE 2224
            V   +  T+    G  +      + +  +   +K  G +++I+    P+  G   +    
Sbjct: 1435 VGRPMPETFWFHDGQQI------VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQN 1488

Query: 2225 AQGHST-----RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
              G S+      +E  E ++ P  FV +L+   ++ EG  +  E +V    +PN  I + 
Sbjct: 1489 RAGRSSISVILTVEAVEHQVKP-MFVEKLKNV-NIKEG--SQLEMKVRATGNPNPDIVWL 1544

Query: 2280 HNGKAL--QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             N   +      +  I    G  +L I   V +D+  Y+  AIN  G  T+   + V  +
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604

Query: 2338 GSIISESQR---PEGLEKIRELESAE-----------PFKRPEIPEPVTRQRPVFTQPLQ 2383
             +     ++   P G  + +E+ + E            ++  ++ +   +Q+P F + L 
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLT 1664

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++  ++    AHF+CRL P+GDPT+ VEW  + K +E ++R+   ++FGY S+       
Sbjct: 1665 SL-RLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYS 1723

Query: 2444 EDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE--- 2500
             D G+  CRA+N  G               +  E+Q PEG K +Q++E+  ER + E   
Sbjct: 1724 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEE-LERMAHEGAL 1782

Query: 2501 -----PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555
                   +E +KP    +   P  + EG+ A +  RV   G P  +  WY+NG  ++   
Sbjct: 1783 TGVTTDQKEKQKPDIV-LYPEPVRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSK 1839

Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            RFR  +D G   LDI    + D G     A N  G
Sbjct: 1840 RFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1873



 Score =  147 bits (356), Expect = 1e-33
 Identities = 112/386 (29%), Positives = 180/386 (46%), Gaps = 22/386 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGH-RYRTFHDFGI 3339
            P F+ ++++V  + EG     + R     +PD  + W  N   + PH + + R     G 
Sbjct: 1510 PMFVEKLKNVN-IKEGSQLEMKVRATGNPNPD--IVWLKNSDIIVPHKYPKIRIEGTKGE 1566

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDST--KANLKCTSKE-----NLILDSQLPRGMEG 3392
              L I     ++S  Y   A NK GRD+T  K N++    E      LI+     R  E 
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 3393 GLEKLQTLEDSMVRRK---DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
               +L+ L     + +       ++EK + P F   L+++   R G  AHFE RLTP  D
Sbjct: 1627 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGP-AHFECRLTPIGD 1685

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P + VEW  +GK L+A +R R   +FG+  L+    Y  DSG   CRA N YG   T+A+
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745

Query: 3510 MKVQGKRNIILESQLPKGMEGTIDKIAALE--GYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
            + V+ +++++ ESQLP+G +G + +I  LE   + G +  +T + +    P+    P  +
Sbjct: 1746 LIVKDEKSLVEESQLPEGRKG-LQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1804

Query: 3568 ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDA 3627
             + E  +A F CR+        +V W+ NG+ +    R +   D G   L+I      D 
Sbjct: 1805 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1861

Query: 3628 GLYTCKATNRHGEATVSCKLQVKGRQ 3653
            G     A N  G      KL+++ R+
Sbjct: 1862 GEVKVTAENPEGVIEHKVKLEIQQRE 1887



 Score =  146 bits (354), Expect = 2e-33
 Identities = 76/204 (37%), Positives = 109/204 (53%), Gaps = 4/204 (1%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP      Q V V SG+  R    ++G     + W K  + +    + K L +   YTLL
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            ++EA+P+D+  Y C A N  G A   A   V +P   +   P  +    PP II PL+D 
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP---EVVSPDQEMPVYPPAIITPLQDT 3308

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            + +EGQ   F C++ G  L  V WY  DK IKPS++F+M++  D Y L I+EA+PEDEG 
Sbjct: 3309 VTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 3367

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPD 4716
            Y  VA N+ G+V+  A L +  P+
Sbjct: 3368 YTFVASNAVGQVSSTANLSLEAPE 3391



 Score =  142 bits (344), Expect = 3e-32
 Identities = 113/391 (28%), Positives = 184/391 (47%), Gaps = 33/391 (8%)

Query: 1836 VEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY- 1893
            VE   +Q  P F+ +L     + EG  +  E ++    +PN  + W  N  ++   H+Y 
Sbjct: 1501 VEAVEHQVKPMFVEKLKN-VNIKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVP-HKYP 1556

Query: 1894 --RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ--------SKESII 1943
              R     G AAL I +   +DS  YT  AIN  G+  +  ++NV+         ++ II
Sbjct: 1557 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1616

Query: 1944 RDSQHESA------LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHL 1997
                + +       LE +       +++     D    +KP F K + +  +    P H 
Sbjct: 1617 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHF 1676

Query: 1998 EATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNA 2057
            E  LTP+ DPTM VEW  +G+P++  +R +   +FGY +LD   AY+ D+G   C+ATN 
Sbjct: 1677 ECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNK 1736

Query: 2058 VGEAVTTSSVKV-DAKSGLYLDTLDEQR--LKKIQELEKYERPKPI----EEEQPGQRPV 2110
             G   T++++ V D KS +    L E R  L++I+ELE+      +     +++  Q+P 
Sbjct: 1737 YGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPD 1796

Query: 2111 FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALD 2170
             +     +  L EG+ A F CRV     P   ++W+ NGQ IR   R+R  +D G   LD
Sbjct: 1797 IVLYPEPVRVL-EGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLD 1852

Query: 2171 ILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            I+   + D+G     A N  G   +   L++
Sbjct: 1853 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883



 Score =  139 bits (337), Expect = 2e-31
 Identities = 118/441 (26%), Positives = 191/441 (43%), Gaps = 29/441 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN--RLTTMHDFGYV 1768
            P+F   +K++ + E   +  E ++   G+P   + WL+N   I      ++      G  
Sbjct: 1510 PMFVEKLKNVNIKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1567

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK-ASLQLESQ----------HESA 1817
            AL +     +DS  YT  AIN+ G   T   + V+ + A  + E +           E A
Sbjct: 1568 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1627

Query: 1818 LQKIQQLE---DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874
              +++ L       +++  +  +    Q P F  +L    +L     AH+ECR+ P  DP
Sbjct: 1628 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPIGDP 1686

Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934
             M VEW  +GK L++ +R R  N+FG+ +LD    Y  DSG  TC+A N  G   +S  L
Sbjct: 1687 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1746

Query: 1935 NVQSKESIIRDSQHESALEKIQYLEDDSRYKR-----AVQDDSFVVEKPQFGKPIKNAEV 1989
             V+ ++S++ +SQ     + +Q +E+  R         V  D    +KP      +   V
Sbjct: 1747 IVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1806

Query: 1990 TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGT 2049
             EG        +T    P  +V WY NG+ +++  RF+  YD G   LDI+   + DTG 
Sbjct: 1807 LEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGE 1863

Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRP 2109
                A N   E V    VK++ +      ++  +  +   E   +E  K   E Q   RP
Sbjct: 1864 VKVTAENP--EGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRP 1921

Query: 2110 VFLTALTSLENLKEGDRAHFE 2130
            V  T    +  LK  +R   E
Sbjct: 1922 VDTTETKEVVKLKRAERITHE 1942



 Score =  136 bits (330), Expect = 1e-30
 Identities = 116/410 (28%), Positives = 186/410 (45%), Gaps = 44/410 (10%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F K ++  +V E ++A FE E   EP   ++W +++  ++ +   +I        L+I  
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPS 3072

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              + D+  +  VA     TAK    L VE +  + R            + V V   Q   
Sbjct: 3073 TRMSDAGKYTVVAGGNVSTAK----LFVEGRDVRIRS---------IKKEVQVIEKQRAV 3119

Query: 4533 LDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            ++ +V     +D +W K+G ++  Q   R+K + E   + + I E    D+G+Y  VA  
Sbjct: 3120 VEFEVN-EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA-- 3176

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
              G  R      V+ P               PP++++ L+   V  G+   F   I G+P
Sbjct: 3177 --GRNRSSVTLYVNAPE--------------PPQVLQELQPVTVQSGKPARFCAVISGRP 3220

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P + WYK ++L+      +      EYTL + EAFPED   Y C A N  G  T +A L
Sbjct: 3221 QPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASL 3280

Query: 4711 -----KVTQPDQADNL--PA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                 +V  PDQ   +  PA +TPL+D V  EGQPA+F+ ++ S     + W  +   I 
Sbjct: 3281 SVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIK 3339

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  F+M    +   L I   Y ED GT+T  A+ A GQV ++A L +++
Sbjct: 3340 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3389



 Score =  134 bits (324), Expect = 7e-30
 Identities = 128/502 (25%), Positives = 219/502 (43%), Gaps = 32/502 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++  K     HFEC + P  DPT+ +EW  + KPL +  R +  ++F Y SLD 
Sbjct: 1659 FKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDY 1718

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE-AR 2894
               Y  DSGI TC+ATN  G+  TS +L    +K++  ++Q P+G+ GL+ +E+ E  A 
Sbjct: 1719 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1778

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
                   +    E  KP+ I+      +++EG+      +V     P  K+ WY NG+++
Sbjct: 1779 EGALTGVTTDQKEKQKPD-IVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQLI 1835

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN---LIE 3011
             +  RF++  D G   LD+VD    D+G     A N  G       +    +++   ++ 
Sbjct: 1836 RKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLR 1894

Query: 3012 RTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQ-IAHY-- 3068
            R   P+    + +   L+  ++K           RP + TT  K++V +   + I H   
Sbjct: 1895 RAPEPRPEFHVHEPGKLQFEVQK---------VDRPVD-TTETKEVVKLKRAERITHEKV 1944

Query: 3069 --EASLIPTGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMV--VLEILGTKTTDSGTYSC 3123
              E+  + +  +    E +Y   T +E   R +      ++    + L   T +      
Sbjct: 1945 PEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEK 2004

Query: 3124 RATNKWGQAEI-SVKLECVDKSKGQK-PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181
            +A  + G+  I + K + ++ S   + P+    IQ+ + +  G  AHF   VV   DP+ 
Sbjct: 2005 KALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC 2063

Query: 3182 KIEWYHNGQPMRHSTRIKTV-SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
              EWY NG  +  S RI     +     L I      DS   + +A N  GE  + A + 
Sbjct: 2064 --EWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLL 2121

Query: 3241 CYGKGGVYLESLQPDSLAKIRE 3262
               K  +       D +AK ++
Sbjct: 2122 VQAKQLITFTQELQDVVAKEKD 2143



 Score =  133 bits (322), Expect = 1e-29
 Identities = 139/532 (26%), Positives = 224/532 (42%), Gaps = 76/532 (14%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P     ++ + V   + A F A  +  G P+ ++ W +    +    +   +HD    
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCA--VISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3248

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L +    PED+  YTC A N+ G A TS        ASL +E     +           
Sbjct: 3249 TLLLIEAFPEDAAVYTCEAKNDYGVATTS--------ASLSVEVPEVVS----------- 3289

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
                  D E+ V   P  IT L   T  SEGQ A ++CR+      +++V WY   K ++
Sbjct: 3290 -----PDQEMPV-YPPAIITPLQD-TVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIK 3339

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS-Q 1947
                +R +       L+I   Y ED G YT  A N +GQ  S+  L++++ ESI+ +  +
Sbjct: 3340 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIE 3399

Query: 1948 HESALEKIQY------LEDDSRYKRAVQ-----------------DDSFVVEK----PQF 1980
             E  +E  ++       E++  +   +Q                    F  EK    P F
Sbjct: 3400 QEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIF 3459

Query: 1981 GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDIL 2040
             K + NA+++ G    L  T+  +  P  +++W+ NG  +     +K  +D    +L IL
Sbjct: 3460 IKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSLIIL 3517

Query: 2041 YAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPI 2100
            +   ED G Y C A+N  G+ + ++ +K+++K   + DT  E  + K   LEK   P P 
Sbjct: 3518 FTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--SLEKLGGPCP- 3574

Query: 2101 EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT 2160
                    P FL  L  +    +G  A FE  V  + +P  T+ WF   +++     Y  
Sbjct: 3575 --------PHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTI 3623

Query: 2161 THD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
             H+  G     +     EDSG Y+CKA N LGE+     L V      + DT
Sbjct: 3624 IHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 3675



 Score =  128 bits (309), Expect = 5e-28
 Identities = 102/387 (26%), Positives = 167/387 (43%), Gaps = 25/387 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF---RFGY 693
            P F+  LK+V   EG ++  E ++   G+P   I WLKN   I    ++  I      G 
Sbjct: 1510 PMFVEKLKNVNIKEGSQL--EMKVRATGNPNPDIVWLKNSDII-VPHKYPKIRIEGTKGE 1566

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT--------------PRATIERTSQ 739
             +L + S   QDS  YT  A++  G   T+  ++V               PR T      
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 740  HPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSD 799
                L+ +       +++  +  +++  Q+P F + L  L  L+    AHFE +LTP+ D
Sbjct: 1627 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPIGD 1685

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PTM VEW  DG+P+ A++R+  I  FGY SL+     + D+G  T RA NK G   ++A+
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745

Query: 860  IRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQI 919
            + V    ++  +  +PE R+ +++                    +  QKP+      + +
Sbjct: 1746 LIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEPV 1804

Query: 920  SIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDA 979
             + EG  A F  R+   G    +V W  +G+ +  S R    ++ G   L I     +D 
Sbjct: 1805 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1861

Query: 980  GHYTCRAYNAIGQATTSANLTIVTKKD 1006
            G     A N  G       L I  ++D
Sbjct: 1862 GEVKVTAENPEGVIEHKVKLEIQQRED 1888



 Score =  126 bits (305), Expect = 1e-27
 Identities = 85/307 (27%), Positives = 136/307 (44%), Gaps = 16/307 (5%)

Query: 66   PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            PGEP+ P F       +  +GG+  F  ++ GNP P V W +   PL    +Y + YN+Q
Sbjct: 1030 PGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1089

Query: 126  TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR----- 180
            TG+  L+I      D GEYT   RN++GE   S  +  E              Y+     
Sbjct: 1090 TGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1149

Query: 181  -----HVSETVEHKAYG--TQGYTTEQSRQTQKVAYTNGTDHSSTDD--FKVDTFEYRLL 231
                  V ET     Y    + Y  EQ+   +K+A       +  +D  F + +FE RL+
Sbjct: 1150 FVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1209

Query: 232  REVSFR-ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLS 290
            +E+ +R    T   + E D +    +D S           + +N ++ EG    F  ++S
Sbjct: 1210 KEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMS 1269

Query: 291  GNPRPRVTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            G P P++ W+K+G+R+ +  ++++        +LR+      D G YT  A N  G  + 
Sbjct: 1270 GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAIC 1329

Query: 350  SGYLAVE 356
            SG L VE
Sbjct: 1330 SGKLYVE 1336



 Score =  126 bits (305), Expect = 1e-27
 Identities = 165/633 (26%), Positives = 257/633 (40%), Gaps = 93/633 (14%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            GR     ++ K+ V + E Q A  E  +    +  +   W+ +G  I    + R  Y   
Sbjct: 3098 GRDVRIRSIKKE-VQVIEKQRAVVEFEV---NEDDVDAHWYKDGIEINFQVQERHKYVVE 3153

Query: 3105 MVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
              +  + I  T+ +D+G Y+  A    G+   SV L     +  + P+    +Q +  ++
Sbjct: 3154 RRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV---NAPEPPQVLQELQPVT-VQ 3205

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G+ A F C V+    P  KI WY   Q +    + K + D     L +      D+  Y
Sbjct: 3206 SGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVY 3263

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282
             C A N YG   T A+++                     E+  +    Q+ P      PP
Sbjct: 3264 TCEAKNDYGVATTSASLSV--------------------EVPEVVSPDQEMP----VYPP 3299

Query: 3283 KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
              IT +QD T   EGQ A F+ R   V   DLKV W+   KK+     +R         L
Sbjct: 3300 AIITPLQD-TVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQL 3355

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLI---LDSQLPRGM--------- 3390
            +I   Y E+ G Y  VA+N +G+ S+ ANL   + E+++   ++ ++   M         
Sbjct: 3356 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLS 3415

Query: 3391 --EGGL-----------EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGEN 3437
              E GL           E L+ L +S V       E+E G  P+F   +SN + +  G+ 
Sbjct: 3416 AEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKE-GTGPIFIKEVSNAD-ISMGDV 3473

Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRA 3497
            A     +T    P  K++W++NG  L   + ++   D     L I  T  ED GEY C A
Sbjct: 3474 ATLS--VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMA 3531

Query: 3498 YNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP 3557
             N+YG+ + +A +K+  K     E       E  + K  +LE   G             P
Sbjct: 3532 SNDYGKTICSAYLKINSKG----EGHKDTETESAVAK--SLEKLGGPC-----------P 3574

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI-NDFGFVI 3616
            P F      +  ++   A FE  +  V + +  V WF   K L T      I N  G   
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGT 3632

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              +    + D+GLY CKA N  GE+T + +L V
Sbjct: 3633 FIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score =  124 bits (300), Expect = 6e-27
 Identities = 132/499 (26%), Positives = 213/499 (42%), Gaps = 75/499 (15%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            K+ W+K  Q ++ G + + +HD     L +I+   ED+ +YTC A N  G    S  L+ 
Sbjct: 3223 KISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
                ++V   Q                        E+    P   T L++    EGQ A 
Sbjct: 3283 E-VPEVVSPDQ------------------------EMPVYPPAIITPLQDTVTSEGQPAR 3317

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656
            F+ R   VS   LKV WY  +K +K    F  T       L+I    PED GTYT  A N
Sbjct: 3318 FQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASN 3374

Query: 1657 ALGE-AVTSGI------AIVHSK------------KSIYLESQHEG------ALPRLNQ- 1690
            A+G+ + T+ +      +I+H +             S +L ++ EG       L ++N+ 
Sbjct: 3375 AVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINET 3434

Query: 1691 LEDTSKYQRHSAQ--DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748
            LE  S+   +S +   E     P+F   + +  ++    A     +I  G PK +++W  
Sbjct: 3435 LELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVI--GIPKPKIQWFF 3492

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
            NGV +  S     + D    +L + +   ED G YTC A N+ G+ + S+ L + SK   
Sbjct: 3493 NGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEG 3552

Query: 1809 QLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRI 1868
              +++ ESA+ K   LE           ++     P F+ +L  P + ++G  A +E  +
Sbjct: 3553 HKDTETESAVAK--SLE-----------KLGGPCPPHFLKELK-PIRCAQGLPAIFEYTV 3598

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
               P P   V W+   K L +   Y    N  G     +     EDSG Y CKA N LG+
Sbjct: 3599 VGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGE 3656

Query: 1928 AVSSIRLNVQSKESIIRDS 1946
            +  +  L V  +++ + D+
Sbjct: 3657 STCAAELLVLLEDTDMTDT 3675



 Score =  122 bits (293), Expect = 4e-26
 Identities = 135/561 (24%), Positives = 226/561 (40%), Gaps = 79/561 (14%)

Query: 3643 VSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETL---HKREEITIEDEKPNPPRFTV 3699
            +    QV+ R   ++E ++   F S T      E T      R  +T+    P PP+   
Sbjct: 3138 IEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQ 3197

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
            E++  + V  G P  F C V   G P  +I W+   +  +TG +   L+D     L +  
Sbjct: 3198 ELQP-VTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE 3254

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
             +  DA  YTC A N +G ATT+A ++           ++P+ +S ++            
Sbjct: 3255 AFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQ------------ 3292

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              E P+   PP  IT ++     E +  RF+CRV   +   L++ WY   K +     +R
Sbjct: 3293 --EMPVY--PPAIITPLQDTVTSEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFR 3345

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII---LQNQVPRG 3936
                     L+I   Y ED G Y   A N  G+  + A +S +    I+   ++ ++   
Sbjct: 3346 MTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEME 3405

Query: 3937 MK---------RSEALTQMEATIKKYTSEV-YLTEDDLY----DVDKK-QPPRFVTQI-Q 3980
            MK           E L   E  + K    +  L+E  +Y    D +K+   P F+ ++  
Sbjct: 3406 MKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSN 3465

Query: 3981 SQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYP 4040
            +  S+ ++ T      +  +G P  K++WFFNG  L     +  ++D    ++   +   
Sbjct: 3466 ADISMGDVAT----LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKL 3521

Query: 4041 EDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHM-KSIEKIREMEASWQVTPE 4099
            ED GEY C A+N YG     A +K   K     D++    + KS+EK+            
Sbjct: 3522 EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKL------------ 3569

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
                     CPP F+     +   +G  A F   V G P P V W      +     Y +
Sbjct: 3570 ------GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTI 3623

Query: 4160 TY--DGMYHFDIPKTRQYDTG 4178
             +  +G   F +   ++ D+G
Sbjct: 3624 IHNPNGSGTFIVNDPQREDSG 3644



 Score =  121 bits (291), Expect = 7e-26
 Identities = 89/309 (28%), Positives = 139/309 (44%), Gaps = 13/309 (4%)

Query: 278   QEGADAQFQVQLSG-NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +EG   ++  ++   +   +VTW+   ++L NS K+EI        L V++  K D G Y
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 337   TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
                  N  G   +   L V+   E Y  D   +      +R T+  + + E+   P+F  
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVY--DYYCRRTMKKIKRRTDT-MRLLERP--PEFTL 25197

Query: 397   VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES--GNHALMITN 454
                ++    G+  RF   +T  P P VTW+ + ++I+   N K    ES  G + L I +
Sbjct: 25198 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 25257

Query: 455   VTLSDSGVVTCVARNKSGETAFQCRLNVI----EKEQVVAPKFVERFSTLNVREGEPVVL 510
             VT  D    T VARNK GE + + +L V       +  + P F    +    +EG+ V  
Sbjct: 25258 VTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCF 25317

Query: 511   NARAVGTPTPRITWQKDGVPIIPNPELRIHTDG-GASTLDIPRAKASDAAWYQCTAQNVA 569
               R  G P P + W+KDG P+   P + I  +G     L I      D  +Y+ TA N A
Sbjct: 25318 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTA 25377

Query: 570   GSTATRARL 578
             GST+ +A L
Sbjct: 25378 GSTSCQAHL 25386



 Score =  120 bits (290), Expect = 1e-25
 Identities = 130/547 (23%), Positives = 230/547 (42%), Gaps = 82/547 (14%)

Query: 1831 QRREDVEVAVN--QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
            + R  V + VN  + P+ + +L  P  +  G+ A +   I   P P  ++ WY   ++L 
Sbjct: 3178 RNRSSVTLYVNAPEPPQVLQELQ-PVTVQSGKPARFCAVISGRPQP--KISWYKEEQLLS 3234

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
            +G + +  +D     L ++  + ED+  YTC+A N+ G A +S  L+V+  E +  D + 
Sbjct: 3235 TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE- 3293

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008
                                      V  P    P+++   +EG P   +     V+   
Sbjct: 3294 ------------------------MPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTD 3326

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            ++V WY   + ++    F+ T       L+I  AY ED GTY   A+NAVG+  +T+++ 
Sbjct: 3327 LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 3386

Query: 2069 VDAKSGLYLDTLDEQ-------------------------RLKKIQELEKYERPKPI--- 2100
            ++A   +  + ++++                         +L KI E  +     P+   
Sbjct: 3387 LEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYST 3446

Query: 2101 --EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158
              + E+ G  P+F+  +++ + +  GD A     V  I  P   I WF NG  +     Y
Sbjct: 3447 KFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADY 3503

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLE 2218
            +   D    +L IL+T  ED G Y C A+N  G+ + +  LK+        DT+  + + 
Sbjct: 3504 KFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVA 3563

Query: 2219 KIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEF 2278
            K   LE  G             PP F+ EL+      +G  A FE  V  V +P   + +
Sbjct: 3564 K--SLEKLGGP----------CPPHFLKELK-PIRCAQGLPAIFEYTV--VGEPAPTVTW 3608

Query: 2279 YHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
            +   K L ++  + I  +  G  +  +     ED+G Y  KA N LG  T A  + V  +
Sbjct: 3609 FKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLE 3668

Query: 2338 GSIISES 2344
             + ++++
Sbjct: 3669 DTDMTDT 3675



 Score =  120 bits (290), Expect = 1e-25
 Identities = 128/511 (25%), Positives = 212/511 (41%), Gaps = 72/511 (14%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E PQ  + ++   V  G P    A ++    P  ++ WY   + +  G + K  +D    
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3248

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L ++ A+ ED   Y C+A N  G A T++S+ V                    E+ +  
Sbjct: 3249 TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------------------EVPEVV 3288

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
             P   ++E P   P  +T L       EG  A F+CRV   +   L + W+   +KI+  
Sbjct: 3289 SP---DQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPS 3341

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII------- 2208
              +R T       L+I   Y ED GTY   A+N +G+  +T  L +    +I+       
Sbjct: 3342 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3401

Query: 2209 LDTQHPNGLEKIRQLEAQG-HSTRIEVE----------EPKISPPRFVTELRGTTHVFEG 2257
            ++ +           E +G HS  +++           E  +   +F +E  GT  +F  
Sbjct: 3402 IEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIK 3461

Query: 2258 KTAHFECQVEPVHD--------PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
            + ++ +  +  V          P  +I+++ NG  L  +A +   FD    SL I     
Sbjct: 3462 EVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKL 3521

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPE 2369
            ED GEY+  A N  G    +  + + +KG         EG  K  E ESA      ++  
Sbjct: 3522 EDEGEYTCMASNDYGKTICSAYLKINSKG---------EG-HKDTETESAVAKSLEKLGG 3571

Query: 2370 PVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH 2429
            P     P F + L+ I    +G  A F+  +  VG+P   V WF+  K +  S   T  H
Sbjct: 3572 PCP---PHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIH 3625

Query: 2430 D-FGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +  G  +  ++  + ED G+Y+C+A N+LGE
Sbjct: 3626 NPNGSGTFIVNDPQREDSGLYICKAENMLGE 3656



 Score =  115 bits (277), Expect = 4e-24
 Identities = 158/722 (21%), Positives = 281/722 (38%), Gaps = 63/722 (8%)

Query: 3807  KIKELERGRISDAPKEEPIVST-PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
             K   LE   + +      I +T   + +T+ +S TV E E  RF C  + +  P   + W
Sbjct: 26040 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPT--VTW 26097

Query: 3866  YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              R G++L +  R++        + +I  V A D G Y     N  G+   + T++ +K  
Sbjct: 26098 LRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26157

Query: 3926  DIILQNQVPRGMKRSEALTQMEATIKK----------YTSEVYLTEDDLYDVDKKQ---- 3971
                     P  +K  E   +    +K           +   V  TE      +K Q    
Sbjct: 26158 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26217

Query: 3972  --PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF- 4028
               PP+    ++++ S    E  K  C +        +V W+ +GK L     F   Y   
Sbjct: 26218 SAPPKITQFLKAEAS---KEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274

Query: 4029  GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD-SQLPKHMKSIEKI 4087
             G   +    +   D GEY+C  +   G  +T           I    S++ +  KS +K 
Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334

Query: 4088  REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
              E   + +  P+    E  +  P +   L D  TV     A+F  + TG P+P  +W  +
Sbjct: 26335 TESTVTRKTEPK--APEPISSKPVIVTGLQDT-TVSSDSVAKFAVKATGEPRPTAIWTKD 26391

Query: 4148  GNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDY 4206
             G  I  G +YKL+ D G +  +I KT   D+G                  L +    D  
Sbjct: 26392 GKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD-- 26449

Query: 4207  RGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQ 4266
                            T+ Q+  T  +KT E     Q++ V+  + E+  K ++  E +  
Sbjct: 26450 ---------------TEAQKVST--QKTSEITP--QKKAVV--QEEISQKALRSEEIKMS 26488

Query: 4267  QSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNL 4326
             ++  ++K        + L +E+V K +    ++ + +I  +++T  + A    + + +  
Sbjct: 26489 EAKSQEKLALKEEASKVLISEEVKKSA---ATSLEKSIVHEEITKTSQASEEVRTHAEIK 26545

Query: 4327  DQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVG-DKEITRKITST 4385
               + +++    Q+ V  K  I   ++       V +   ++ +  V G D+ +T K  S 
Sbjct: 26546 AFSTQMSINEGQRLVL-KANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASH 26604

Query: 4386  ETTEI-EHKAQTQERVVEGPV------KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438
                 I    ++T+E +V+         + S  P F  + +   + E +   F  E  GEP
Sbjct: 26605 RDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEP 26664

Query: 4439  LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
              P I+W++ N PI  S +  I        L IR   V DS  +   A+N  G    +A+L
Sbjct: 26665 SPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 26724

Query: 4499  VV 4500
             +V
Sbjct: 26725 MV 26726



 Score =  113 bits (271), Expect = 2e-23
 Identities = 143/649 (22%), Positives = 258/649 (39%), Gaps = 54/649 (8%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH-DFGYVALDILYTYAEDSGT 2181
            EG    F C++     P +   W+ +G++I+ G RY+      G  +L I     ED G 
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIA--WYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315

Query: 2182 YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLEAQGHS-TRIEVEEPK 2238
            Y   A+N  G A+ +  L V     +   T  P    + +IR L  +  S + I +   +
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPAR 1375

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHF--ECQVEPVHDPNLRIEFYHNGKALQS-AARFHITF 2295
            +SP R          +  G+      E Q+E ++ P   ++   + K L+   ARF +  
Sbjct: 1376 MSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV-SFKCLEGQTARFDLKV 1434

Query: 2296 DFGYVSLDIQ-HCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQRPEGLEK 2352
                +      H   +   +Y+ K +       S I +  T    G     +Q   G   
Sbjct: 1435 VGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSS 1494

Query: 2353 IRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEW 2412
            I  + + E  +         + +P+F + L+N+ NI+EG  +  + ++   G+P   + W
Sbjct: 1495 ISVILTVEAVEH--------QVKPMFVEKLKNV-NIKEG--SQLEMKVRATGNPNPDIVW 1543

Query: 2413 FRNEKLIEDSS--RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXX 2470
             +N  +I      +I      G  ++ I     +D   Y   A N  G            
Sbjct: 1544 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603

Query: 2471 XXXIQLETQH----PEGMKKIQKLEQP-----HERRSEEP-------DREFE-KPIFTQV 2513
                + E +     P G  + +++  P     H R  +E        D+E + KP F + 
Sbjct: 1604 EFA-EPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1662

Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSV 2573
            LT    L     AH+E R+ P+GDP++  EW  +G  L+  +R R  ++FG+ +LD    
Sbjct: 1663 LTS-LRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVA 1721

Query: 2574 VANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPE-- 2631
             + D+G+  C+A N+ G               +++++  PE  + +Q  E       E  
Sbjct: 1722 YSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGA 1781

Query: 2632 ---MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
               +  D   +Q P    + +   +++EG+      +V     P  K+ W+ NG  +   
Sbjct: 1782 LTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKS 1838

Query: 2689 ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             R +  +D G+  L I   ++ D+G     A N  G       ++I+ R
Sbjct: 1839 KRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1886



 Score =  111 bits (266), Expect = 8e-23
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 11/228 (4%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS--PDFQIHTFSTK 4465
            ++ P FT+ +Q   V E   A FE    G P+P + W+R+   I  S  P  QI     +
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            + L I  V   +S  ++  A N  G A  +A L+V+ +         PP+F    Q++ V
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET-------APPNFVQRLQSMTV 115

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  VRL  +VTG     V + ++G ++Q  +  +I +E   Y+LLI EAYP+DSG Y 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
              A NS G A   AE +V     ++ P  +TK   +  +I E  + +I
Sbjct: 176  VNATNSVGRATSTAELLVQ--GEEEVPAKKTKTIVSTAQISESRQTRI 221



 Score =  109 bits (262), Expect = 2e-22
 Identities = 86/289 (29%), Positives = 125/289 (43%), Gaps = 24/289 (8%)

Query: 4545  VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
             V W    ++++   + +I  EDG   L + +    D G Y C  +N  GE    AE  V 
Sbjct: 25103 VTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVK 25162

Query: 4605  ---------LPATKDKPKPQT---KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
                         T  K K +T   +    PPE   PL +K    G+ + F   I   P P
Sbjct: 25163 GVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEP 25222

Query: 4653  TVQWYKGDKLIKP---SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
              V WYK  + IKP    K +        Y L I+    +D+ +Y  VA N  G  +  AK
Sbjct: 25223 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 25282

Query: 4710  LKVT-QPDQADNLPALTP-----LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             L VT  P   D+   L P     L +    EGQ   F+ +++    PT++W ++G  +  
Sbjct: 25283 LTVTLHPPPTDS--TLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSL 25340

Query: 4764  TPDFQMIHEG-NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              P+ ++IHEG +   L I +T  EDTG +   AT  AG     A L V+
Sbjct: 25341 GPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389



 Score =  109 bits (261), Expect = 3e-22
 Identities = 69/234 (29%), Positives = 108/234 (46%), Gaps = 14/234 (5%)

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            A ++  R   A+ S    +EE        +  P F L   +     GQ  R D KV G  
Sbjct: 1379 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRP 1438

Query: 4542 PIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
              + +W  +G+++  D  +K+ ++EDGT +L+I+ A P DSG++  VA N AG  R    
Sbjct: 1439 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG--RSSIS 1496

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             ++++ A + + KP           +E LK+  + EG  +E   +  G P P + W K  
Sbjct: 1497 VILTVEAVEHQVKPM---------FVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNS 1547

Query: 4661 KLIKPSKY--FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +I P KY   ++  T  E  L+I     +D   Y   A N AGR T   K+ V
Sbjct: 1548 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601



 Score =  107 bits (256), Expect = 1e-21
 Identities = 179/750 (23%), Positives = 286/750 (38%), Gaps = 90/750 (12%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYING--VELKMGSRFRTTHDFG 2564
            KP+F + L   + + EG  +  E +V   G+P+    W  N   +      + R     G
Sbjct: 1509 KPMFVEKLKNVN-IKEG--SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKG 1565

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXX--------IIDQAM-RPES 2615
               L I+S V+ D+  Y   AIN+AG                       II +   R + 
Sbjct: 1566 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKE 1625

Query: 2616 WEQIQLKEAAMNKVPEMF-----VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRT 2670
                +L+   +    E +      D   QQ P F   L S  +L      + E ++ P  
Sbjct: 1626 IAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPIG 1684

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DP + +EW  +G  L    RL+   +FG  +L      + DSGI TC+ATN  G   ++A
Sbjct: 1685 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1744

Query: 2731 SIKIEDRHWLLGESLHPD---SLDRIGALXXXXXXXXXXXXXXXXXXV----FISHLNNI 2783
            ++ ++D   L+ ES  P+    L RI  L                        + +   +
Sbjct: 1745 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1804

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
               EG+   F C V     P  K+ W+ N + +    R++  +D  +  LDI      D+
Sbjct: 1805 RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYDGIHY-LDIVDCKSYDT 1861

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
            G     A N +G                    +H   K  LE ++Q E+ R    R P  
Sbjct: 1862 GEVKVTAENPEGV------------------IEH---KVKLE-IQQREDFRSVLRRAPE- 1898

Query: 2904 PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLK-IEWYFNGKVLEQG----S 2958
                 P+PE+ +    + Q    +V       E K    LK  E   + KV E+     S
Sbjct: 1899 -----PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRS 1953

Query: 2959 RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKG 3018
            +FK  ++ G+   + +   E  S         K+ E++    +   +KD L+  T+  + 
Sbjct: 1954 KFKRRTEEGY--YEAITAVELKS--------RKKDESY--EELLRKTKDELLHWTK--EL 1999

Query: 3019 TEGLEKIQNLEDSLRKEPGQQPDDDTGRPP-EFTTVFKDIVD--ISEGQIAHYEASLIPT 3075
            TE  EK    E+     P  +PD     P  E   +F+ I    + +G  AH+   ++  
Sbjct: 2000 TEE-EKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVV-- 2056

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAEI 3134
            G      EW+ NG  IE S RI   +    V  L I      DS +   +A N  G+   
Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L    K   Q   FT  +Q++   +    A FEC      +P +K++WY +G  +  
Sbjct: 2117 HAFLLVQAK---QLITFTQELQDVVAKEKDTMATFEC---ETSEPFVKVKWYKDGMEVHE 2170

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              + +  SD     L I      D+ +Y C
Sbjct: 2171 GDKYRMHSDRKVHFLSILTIDTSDAEDYSC 2200



 Score =  105 bits (252), Expect = 4e-21
 Identities = 128/514 (24%), Positives = 209/514 (40%), Gaps = 78/514 (15%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++ G  A F A +   G    ++ W K+ + +    +     +     L +      D
Sbjct: 3202 VTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 3259

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK 1038
            A  YTC A N  G ATTSA+L++   + +  + + P                        
Sbjct: 3260 AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP------------------------ 3295

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
                P  + PL+ T    EGQ A F+ RV   S   + V WY   K+I  +   +     
Sbjct: 3296 -VYPPAIITPLQDT-VTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI--------------DTS 1144
                L+IA    ED G YT VA NA G+   +A++++E   SI              + S
Sbjct: 3351 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFS 3410

Query: 1145 SIHRGLYEKTRHIEE---SKFVE--------PMYQIEEISKSK---PVFVQPLSNPPPVS 1190
            S      E+  H  E   SK  E        P+Y  +  S+ +   P+F++ +SN   +S
Sbjct: 3411 SSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSN-ADIS 3469

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
             G    L   +  +G P  +++WF NG  +T  + +K  +D    +L I+     D GEY
Sbjct: 3470 MGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEY 3527

Query: 1251 TVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA 1310
            T  A N  G    SA +++  + +   DT+ E A+             K + E +     
Sbjct: 3528 TCMASNDYGKTICSAYLKINSKGEGHKDTETESAV------------AKSL-EKLGGPCP 3574

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L  I   +G     E  +  VG+    V WF   K + T   +   +  +    
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGT 3632

Query: 1371 DLLS-VYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             +++    EDSG+Y C+A N LGE+  +  L V+
Sbjct: 3633 FIVNDPQREDSGLYICKAENMLGESTCAAELLVL 3666



 Score =  104 bits (249), Expect = 9e-21
 Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 19/258 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN--KILEEDGTYTL 4571
            P+FT   Q+V V  G     +  ++G    +V W ++G+ +        +I   DG   L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      +SG+Y   A N +G+A   AE +V             KA  APP  ++ L+ 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------KAETAPPNFVQRLQS 112

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V +G  +    ++ G P P V++Y+    I+ S  FQ+S+  D Y+L I+EA+PED G
Sbjct: 113  MTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK-- 4749
             Y   A NS GR T  A+L V   ++       T +    + E +  + + +I +     
Sbjct: 173  TYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDAR 232

Query: 4750 --PTIQWLREGALIPETP 4765
               T++ + +GA   + P
Sbjct: 233  SIATVEMVIDGAAGQQLP 250



 Score =  104 bits (249), Expect = 9e-21
 Identities = 170/774 (21%), Positives = 288/774 (37%), Gaps = 105/774 (13%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            ++ +W  NG +I S ++ Q        +L+I +V   D+  YT VA  A   A L     
Sbjct: 2951 ISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEAR 3010

Query: 1135 -VETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGK 1193
             +E R  I    +     EK R + E +  EP   ++ +   + +    +++   + + K
Sbjct: 3011 HIEFRKHIKDIKV----LEKKRAMFECEVSEPDITVQWMKDDQEL---QITDRIKIQKEK 3063

Query: 1194 NIHL----ECRLEPMGDPTM-------RVEWFHNGRSVTVGSRFKTYYDFGFVALDI--- 1239
             +H       R+   G  T+         + F  GR V + S  K           +   
Sbjct: 3064 YVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFE 3123

Query: 1240 IHATSADTGEYT--VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARR 1297
            ++    D   Y   +     +   H   + R I R   +++T+   A E   +   A R 
Sbjct: 3124 VNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM-FISETRQSDAGEYTFV---AGRN 3179

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
               V   +   + PQ  + L  +    G      C +   G    ++ W+   + + TG 
Sbjct: 3180 RSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGF 3237

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSG 1417
            + +  ++     L L+  +PED+ VYTC+A N  G A TS +L V   + +  + + P  
Sbjct: 3238 KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP-- 3295

Query: 1418 LEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK 1477
                                    + P  +  P       EGQ   F+C+   V+ ++LK
Sbjct: 3296 ------------------------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLK 3328

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            V W+   + +     FR         L+I +   ED G YT  A N VG    +  L+  
Sbjct: 3329 VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3388

Query: 1538 STTDIVRS------------------TQNEAGLEQIQV----------LEDRSKYHRTDM 1569
            +   I+                    +  E GL   ++          L   S  + T  
Sbjct: 3389 APESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKF 3448

Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629
              E     PI    + N +I  G  A     +I +     K++W+ N   L   + +   
Sbjct: 3449 DSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFV 3506

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN 1689
             +    +L I+    ED G YTC A N  G+ + S    ++SK   + +++ E A+ +  
Sbjct: 3507 FDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK-- 3564

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRN 1749
             LE                  P F   +K IR A+   A FE  +  VG+P   V W + 
Sbjct: 3565 SLEKLGG-----------PCPPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKE 3611

Query: 1750 GVPIEASNRLTTMHD-FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
               +  S   T +H+  G     +     EDSG Y C+A N LGE+  ++ L V
Sbjct: 3612 NKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score =  103 bits (247), Expect = 2e-20
 Identities = 124/483 (25%), Positives = 190/483 (39%), Gaps = 78/483 (16%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W+   Q +  G + +  HD     L ++  + ED+  Y C+A N  G A  + +
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279

Query: 2199 LKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            L V     +  D + P                        + PP  +T L+ T    EG+
Sbjct: 3280 LSVEVPEVVSPDQEMP------------------------VYPPAIITPLQDTV-TSEGQ 3314

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT-FDFGYVSLDIQHCVPEDAGEYSV 2317
             A F+C+V      +L++ +Y   K ++ +  F +T F+  Y  L+I    PED G Y+ 
Sbjct: 3315 PARFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTY-QLEIAEAYPEDEGTYTF 3370

Query: 2318 KAINALGHCTSAISMTVTAKGSIISE------------------SQRPEGLE-------K 2352
             A NA+G  +S  ++++ A  SI+ E                  S   EGL        K
Sbjct: 3371 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3430

Query: 2353 IRE---LESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            I E   L S  P    +         P+F + + N D I  G  A     +I  G P  K
Sbjct: 3431 INETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTVI--GIPKPK 3487

Query: 2410 VEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXX 2469
            ++WF N  L+  S+      D    S+ I   + EDEG Y C ASN  G+          
Sbjct: 3488 IQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKIN 3547

Query: 2470 XXXXIQLETQHPEGM-KKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528
                   +T+    + K ++KL  P              P F + L  P    +G  A +
Sbjct: 3548 SKGEGHKDTETESAVAKSLEKLGGPC------------PPHFLKELK-PIRCAQGLPAIF 3594

Query: 2529 EARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAIN 2587
            E  V  VG+P+    W+    +L     +   H+  G  T  +N     D+GLY+CKA N
Sbjct: 3595 EYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3652

Query: 2588 RAG 2590
              G
Sbjct: 3653 MLG 3655



 Score =  102 bits (244), Expect = 4e-20
 Identities = 70/234 (29%), Positives = 108/234 (46%), Gaps = 16/234 (6%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV+PP +    +N  + EG     +  +SG P P VTW++   ++ +S   +I       
Sbjct: 893  PVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIA 952

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE----------SPTESYVQDQR---- 367
             L +R     DSG +T  A N  G + TS YLAV+          + TE +  +++    
Sbjct: 953  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1012

Query: 368  SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            S+ +  T    TEE+    E A AP F+     + + EG    F C+V G P P V W  
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPA-APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071

Query: 428  NDRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            +   +   Y +K+  N ++G   L+I+     D+G  T V RNK GET+    L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score =  101 bits (243), Expect = 5e-20
 Identities = 142/664 (21%), Positives = 262/664 (39%), Gaps = 57/664 (8%)

Query: 3163  DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             +G+SA F C      +P   + W   GQ +  S R +  +       +I+  Q  D G Y
Sbjct: 26077 EGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 26134

Query: 3223  VCRAYNKYGEDFTRATINCYGKGGVYLESL-------QPDSLAKIRE-LESLQGAQQQTP 3274
                  N  G+     T+    K  V  +++        P+   K  E ++S +  +   P
Sbjct: 26135 SVVVENSEGKQEAEFTLTIQ-KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEP 26193

Query: 3275  STPSAEPPKF-------------ITQIQDVTKLVEGQSAHFEARLVPVDDPDL----KVE 3317
             S P A  P               ++    +T+ ++ +++   A+L  V +  +    +V 
Sbjct: 26194 SHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVT 26253

Query: 3318  WFYNGKKLP-HGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
             W+ +GKKL  +GH    +   G   L I    E + GEY C  + + G  ++K NL+   
Sbjct: 26254 WYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGG--TSKTNLQFMG 26311

Query: 3377  KENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGE 3436
             +    +  ++ +  E      +T E ++ R+ +    E     PV    L +   +    
Sbjct: 26312 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT-TVSSDS 26370

Query: 3437  NAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCR 3496
              A F  + T   +P     W  +GK++  G +++   D G   LEI  T   DSG Y C 
Sbjct: 26371 VAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCT 26428

Query: 3497  AYNNYGEAVTTASMKVQGKRNIILES-QLPKGMEGTIDKIAALEGYSG-----TVDTLTP 3550
               N+ G   ++  + ++  ++   +     K  E T  K A ++         + +    
Sbjct: 26429 VKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS 26488

Query: 3551  EAESGNPPEFTTTPSDLILSE----NSSAHFECRLI--PVNDSSMRVEWFHNGKPLLTGS 3604
             EA+S          S +++SE    +++   E  ++   +  +S   E       +   S
Sbjct: 26489 EAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS 26548

Query: 3605  RVKTINDFGFVILE--IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662
                +IN+   ++L+  I G       L   + TN     +   +  V G    +   Q  
Sbjct: 26549 TQMSINEGQRLVLKANIAGATDVKWVLNGVELTN-----SEEYRYGVSGSDQTLTIKQAS 26603

Query: 3663  SHFKSGTESIQKLEETLHK-REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEP 3721
                +     I K +E + K + ++T+  E  + P F  + +   ++ EG  V F C +  
Sbjct: 26604 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQ-NINEGQNVLFTCEIS- 26661

Query: 3722  VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
              G+P+  I+WF N  P +  S V         +L+I      D+G+YT +A N  G  + 
Sbjct: 26662 -GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSA 26720

Query: 3782  TAKI 3785
             TA +
Sbjct: 26721 TASL 26724



 Score =  100 bits (240), Expect = 1e-19
 Identities = 76/284 (26%), Positives = 123/284 (43%), Gaps = 8/284 (2%)

Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITS----T 4385
            +EV     Q+ V +     D  ++  +   + +  Q Q + + V ++ I R   S    +
Sbjct: 3108 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3167

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445
            +  E    A      V   V   +PP   +++QP  V   + ARF     G P P I WY
Sbjct: 3168 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3227

Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR- 4504
            +E   +      +      +  L++ + F ED+AV+   A+N  G A  SA+L VE    
Sbjct: 3228 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3287

Query: 4505 --RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                    + PP+     Q+   + GQ  R   +V+GT  + V W    KK++P    ++
Sbjct: 3288 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRM 3346

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
             + + TY L I EAYP+D G Y  VA N+ G+    A   +  P
Sbjct: 3347 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3390



 Score =  100 bits (239), Expect = 1e-19
 Identities = 113/503 (22%), Positives = 189/503 (37%), Gaps = 44/503 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            PQ ++  Q   V  GK  RF   ++GRP P+++W+  ++ +   +  K L ++   + L+
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL-HDGQEYTLL 3251

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLN-----VIEKEQ---VVAPKFVERFSTLNVR 503
            +      D+ V TC A+N  G       L+     V+  +Q   V  P  +         
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            EG+P     R  GT   +++W      I P+   R+        L+I  A   D   Y  
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370

Query: 564  TAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTK-------------VXXXXXXXXX 610
             A N  G  ++ A L           +    +    K             +         
Sbjct: 3371 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3430

Query: 611  XXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKI 670
                L  +  +  Y    + ++    P FI  + +     G        +  +  P  KI
Sbjct: 3431 INETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP--KI 3488

Query: 671  EWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTP 730
            +W  NG  +  S+ +  +F     SL +L   ++D GEYTC A +  G     A L +  
Sbjct: 3489 QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3548

Query: 731  RATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ-RPQFIRPLQDLGELQEGRNAH 789
            +        H +T       E  S     +S+E+      P F++ L+ +    +G  A 
Sbjct: 3549 KG-----EGHKDT-------ETESAV--AKSLEKLGGPCPPHFLKELKPI-RCAQGLPAI 3593

Query: 790  FEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGYVSLNIMHLRAEDAGSYTVRAV 848
            FE   T V +P   V W+K+ + +  S   T I N  G  +  +   + ED+G Y  +A 
Sbjct: 3594 FE--YTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAE 3651

Query: 849  NKLGEAISTASIRVAARSTVTAD 871
            N LGE+   A + V    T   D
Sbjct: 3652 NMLGESTCAAELLVLLEDTDMTD 3674



 Score =   99 bits (238), Expect = 2e-19
 Identities = 139/561 (24%), Positives = 209/561 (37%), Gaps = 77/561 (13%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   Q LQ +  +Q G+ A F C +I  G P  K+ W++ E+L+    +    HD    +
Sbjct: 3193 PQVLQELQPV-TVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3249

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495
            + +     ED  VY C A N  G                 L  + PE +           
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSAS----------LSVEVPEVVS---------- 3289

Query: 2496 RRSEEPDREFEKPIFTQVLTGPSE---LWEGQHAHYEARVVPVGDPSLRFEWYINGVELK 2552
                 PD+E   P++   +  P +     EGQ A ++ RV       L+  WY    ++K
Sbjct: 3290 -----PDQEM--PVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIK 3339

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMR 2612
                FR T       L+I      D G Y   A N  G               I+ + + 
Sbjct: 3340 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIE 3399

Query: 2613 PE-SWEQIQLKEAAMNKVPEMFVDTGVQ------------QAPIFTTHLKS--------Y 2651
             E   E  +   + ++   E      +Q            ++P+++T   S        +
Sbjct: 3400 QEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIF 3459

Query: 2652 DKLVEGQHVYL----EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             K V    + +       V     P  KI+WF NGV LT  A  K  FD    +L I   
Sbjct: 3460 IKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFT 3519

Query: 2708 RNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXX 2767
            + +D G YTC A+N  G+ + +A +KI  +    GE  H D+ +   A+           
Sbjct: 3520 KLEDEGEYTCMASNDYGKTICSAYLKINSK----GEG-HKDT-ETESAVAKSLEKLGGPC 3573

Query: 2768 XXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD 2827
                    F+  L  I C +G    FE  V     PT  + WF  NK L +   Y   H+
Sbjct: 3574 PPH-----FLKELKPIRCAQGLPAIFEYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHN 3626

Query: 2828 FSYVSLDITH-TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEA 2886
             +     I +    EDSG+Y CKA N  G +T +  L    +     DT   + K+  EA
Sbjct: 3627 PNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP-CKAKSTPEA 3685

Query: 2887 VEQAEEARLAKGRRPSVPDTE 2907
             E   +  L KG      D+E
Sbjct: 3686 PEDFPQTPL-KGPAVEALDSE 3705



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 57/193 (29%), Positives = 97/193 (50%), Gaps = 4/193 (2%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYTL 4680
            P   +PL+  +V EG    F   I G P+P V W++  ++I  S     Q+S +     L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             I      + G Y   A N +G+ T  A+L V       N   +  L+ + V +G   + 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNF--VQRLQSMTVRQGSQVRL 123

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + ++T    P +++ R+GA I  + DFQ+  EG+   LLI   Y ED+GT++  AT + G
Sbjct: 124  QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183

Query: 4801 QVETSAKLVVKSK 4813
            +  ++A+L+V+ +
Sbjct: 184  RATSTAELLVQGE 196



 Score = 98.3 bits (234), Expect = 6e-19
 Identities = 87/371 (23%), Positives = 151/371 (40%), Gaps = 56/371 (15%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV PP I    +++   EG  A+FQ ++SG    +V+W+   +++  S    +    +  
Sbjct: 3295 PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3353

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLA-----------VESPTESYVQDQRSQY 370
             L +      D G YT +A N  G + ++  L+           +E   E  +++  S +
Sbjct: 3354 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSF 3413

Query: 371  IT---------DTQQRETEERIEI------------SEK-ALAPQFVKVCQDRDVTEGKM 408
            ++         + Q  +  E +E+            SEK    P F+K   + D++ G +
Sbjct: 3414 LSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDV 3473

Query: 409  TRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
                  V G P P++ WF N   +    ++K  V +  +H+L+I    L D G  TC+A 
Sbjct: 3474 ATLSVTVIGIPKPKIQWFFNGVLLTPSADYKF-VFDGDDHSLIILFTKLEDEGEYTCMAS 3532

Query: 469  NKSGETAFQCRLNV---------IEKEQVVA-----------PKFVERFSTLNVREGEPV 508
            N  G+T     L +          E E  VA           P F++    +   +G P 
Sbjct: 3533 NDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPA 3592

Query: 509  VLNARAVGTPTPRITWQKDGVPIIPNPELR-IHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +     VG P P +TW K+   +  +     IH   G+ T  +   +  D+  Y C A+N
Sbjct: 3593 IFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3652

Query: 568  VAGSTATRARL 578
            + G +   A L
Sbjct: 3653 MLGESTCAAEL 3663



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 60/189 (31%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F +  Q   V EG    F+  ++G P PEV+WF + + I       + ++ S   A 
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I  VT ++SG  +  A N SG+      L V  K +   P FV+R  ++ VR+G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV--KAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L  R  G PTP + + +DG  I  + + +I  +G   +L I  A   D+  Y   A N  
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182

Query: 570 GSTATRARL 578
           G   + A L
Sbjct: 183 GRATSTAEL 191



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 93/361 (25%), Positives = 145/361 (40%), Gaps = 49/361 (13%)

Query: 2508  PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
             P+  Q++    E  EG H  Y  ++    D S +  WY    +L+   ++  T++ G   
Sbjct: 25072 PVSGQIMHAVGE--EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAI 25128

Query: 2568  LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
             L +  +   D G Y CK +N  G               + D   R  + ++I+ +   M 
Sbjct: 25129 LYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCR-RTMKKIKRRTDTMR 25187

Query: 2628  KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                       +++ P FT  L +    V G++V     +    +P+  + W+K+G  +  
Sbjct: 25188 L---------LERPPEFTLPLYNKTAYV-GENVRFGVTITVHPEPH--VTWYKSGQKIKP 25235

Query: 2688  GAR-LKSTF--DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
             G    K TF  D GL  L+INS+  DD   YT  A N  GE    A + +         +
Sbjct: 25236 GDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV---------T 25286

Query: 2745  LHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPT 2804
             LHP   D                       +F   L N  C+EG ++ FE  V     PT
Sbjct: 25287 LHPPPTD------------------STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPT 25328

Query: 2805  LKIEWFFNNKPLPSGTRYKSTHD-FSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             LK  W  + +PL  G   +  H+   Y +L I  T  ED+G Y   ATN+ GS +    L
Sbjct: 25329 LK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHL 25386

Query: 2864  R 2864
             +
Sbjct: 25387 Q 25387



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 93/345 (26%), Positives = 136/345 (39%), Gaps = 41/345 (11%)

Query: 1858  EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
             EG    Y C+IE Y D + +V WYF  + L++  +Y  + + G A L +  +   D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 1918  TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK 1977
              CK +N+ G+  S   L V+    +  D      ++KI+   D  R          +   
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVY-DYYCRRTMKKIKRRTDTMR---------LLERP 25192

Query: 1978  PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
             P+F  P+ N     G  V    T+T   +P   V WY +G+ ++ G              
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDN------------ 25238

Query: 2038  DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             D  Y +  D G Y     +   +     +V    K G       E   K   +L     P
Sbjct: 25239 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG-------EDSCK--AKLTVTLHP 25289

Query: 2098  KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
              P +      RP+F   L + E  +EG    FE RV  I  P  T+ W  +GQ +  G  
Sbjct: 25290 PPTDST---LRPMFKRLLANAE-CQEGQSVCFEIRVSGIPPP--TLKWEKDGQPLSLGPN 25343

Query: 2158  YRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 H+   Y AL I  T  ED+G Y   ATN  G       L+V
Sbjct: 25344 IEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388



 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 96/405 (23%), Positives = 174/405 (42%), Gaps = 52/405 (12%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F + +   +V E E ARFE E   E    +KW+++   IK    + I +     IL+I +
Sbjct: 5879 FLRPLTDLQVREKEMARFECELSRENAK-VKWFKDGAEIKKGKKYDIISKGAVRILVINK 5937

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              ++D A ++        TA+ S  L V E+            FT    N+ V+    ++
Sbjct: 5938 CLLDDEAEYSCEVR----TARTSGMLTVLEEEAV---------FTKNLANIEVSETDTIK 5984

Query: 4533 LDTKVTGTKP-IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            L  +V+  KP  +V W K  +++    R +IL E     L+I  A+ +D+G Y C     
Sbjct: 5985 LVCEVS--KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC----- 6037

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
                         LP+++   K   K      E I   ++  + EG+  EF C I  +  
Sbjct: 6038 ------------RLPSSRTDGK--VKVHELAAEFISKPQNLEILEGEKAEFVCSISKESF 6083

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV--AYNSAGRVTVAAK 4709
            P VQW + DK ++    + +     +  L + +A  +D G Y  +  A  +A  +TV  K
Sbjct: 6084 P-VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEK 6142

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            L++           + PL+D  V E Q   F  ++ ++     +W R    I ++  + +
Sbjct: 6143 LRI-----------VVPLKDTRVKEQQEVVFNCEVNTE-GAKAKWFRNEEAIFDSSKYII 6190

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVVKSK 4813
            + +     L I + + +D   +    T   G+ V+++A L+V+ +
Sbjct: 6191 LQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEE 6235



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 66/243 (27%), Positives = 108/243 (44%), Gaps = 10/243 (4%)

Query: 241  TKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF 300
            T   + ES V  ST+ D       P  I ++  N+ +  G  A   V + G P+P++ WF
Sbjct: 3434 TLELLSESPVY-STKFDSEKEGTGPIFI-KEVSNADISMGDVATLSVTVIGIPKPKIQWF 3491

Query: 301  KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             NG  L  S  ++ +   +  +L +  T+  D G YT +A N  G  + S YL + S  E
Sbjct: 3492 FNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3551

Query: 361  SYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPY 420
             +         T+T+     + +E       P F+K  +     +G    F+  V G P 
Sbjct: 3552 GHKD-------TETES-AVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPA 3603

Query: 421  PEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            P VTWF  ++Q+     + I+ N +G+   ++ +    DSG+  C A N  GE+     L
Sbjct: 3604 PTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 3663

Query: 481  NVI 483
             V+
Sbjct: 3664 LVL 3666



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 105/404 (25%), Positives = 168/404 (41%), Gaps = 44/404 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P + T  ++     E +   FEV  + E +   KW +    IK++   Q+ T      L 
Sbjct: 2922 PIMITSMLKDINAEEKDTITFEVTVNYEGISY-KWLKNGVEIKSTDKCQMRTKKLTHSLN 2980

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            IR V   D+A +  VA    G A  +A L VE +  + R  I         +++ V   +
Sbjct: 2981 IRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHI---------KDIKVLEKK 3027

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
                + +V+    I V W+K+ +++Q   R KI +E   + LLI      D+GKY  VA 
Sbjct: 3028 RAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAG 3086

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
             +   A+   E        +D    + ++     ++IE  K + V     +EF    V +
Sbjct: 3087 GNVSTAKLFVE-------GRD---VRIRSIKKEVQVIE--KQRAV-----VEFE---VNE 3126

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                  WYK    I      +     +   + + ISE    D G+Y  V    AGR   +
Sbjct: 3127 DDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV----AGRNRSS 3182

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              L V  P+    L  L P   + V  G+PA+F   I+ + +P I W +E  L+      
Sbjct: 3183 VTLYVNAPEPPQVLQELQP---VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + +H+G    LL+   + ED   +TC A    G   TSA L V+
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 68/206 (33%), Positives = 91/206 (44%), Gaps = 15/206 (7%)

Query: 4513  PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK--ILEED-GTY 4569
             PP FTL   N     G+ VR    +T      V W K+G+K++P   +K    E D G Y
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 25251

Query: 4570  TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL--PATKDKPKPQTKAANAPPEIIE 4627
              L I      D  +Y  VA N  GE  C A+  V+L  P T    +P  K   A  E   
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAE--- 25308

Query: 4628  PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAF 4686
                     EGQ++ F  ++ G P PT++W K G  L        +    D Y L I +  
Sbjct: 25309 ------CQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTL 25362

Query: 4687  PEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             PED G Y+  A N+AG  +  A L+V
Sbjct: 25363 PEDTGYYRVTATNTAGSTSCQAHLQV 25388



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 146/718 (20%), Positives = 272/718 (37%), Gaps = 57/718 (7%)

Query: 1132  SMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
             S   ETR S+ +         K+  +EE K +E      +I  +    +        V E
Sbjct: 26019 SQMTETRESLSSYEHSASAEMKSAALEE-KSLEEKSTTRKIKTTLAARILTKPRSMTVYE 26077

Query: 1192  GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
             G++    C  +  G+P   V W   G+ ++  +R +          +I    ++D G Y+
Sbjct: 26078 GESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYS 26135

Query: 1252  VRAVNHLGSAH---TSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVR------ 1302
             V   N  G      T  I +       VT     ++ E      +A +  K+V+      
Sbjct: 26136 VVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSH 26195

Query: 1303  -----------------EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVE 1345
                              + + V   P+ ++ L    + E     L C ++    +   V 
Sbjct: 26196 PKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAK--LTCVVESSVLRAKEVT 26253

Query: 1346  WFCNGKPIKTGHRFRPAYEFDYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
             W+ +GK +K    F+  Y  D    L + ++   D G Y C+ + + G + T+      A
Sbjct: 26254 WYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQA 26313

Query: 1405  KKDLILESQHPSGLEKIQY--LEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHV 1462
              K +  +    S  +K      E T   K      E ++ KP  VT    +++       
Sbjct: 26314 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVT---GLQDTTVSSDS 26370

Query: 1463  HFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAV 1522
               +  ++   +      W K+G+ +T G +++   D G   L+I      DSG+YTC   
Sbjct: 26371 VAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK 26430

Query: 1523  NLVGTDEVSCRLTCRSTTDIVR---STQNEAGL---EQIQVLEDRS-KYHRTDMV--DEV 1573
             N  G+   SC+LT ++  D      STQ  + +   ++  V E+ S K  R++ +   E 
Sbjct: 26431 NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEA 26490

Query: 1574  TTQAPI-----CTTSLKNVEIKEGQRAHFERRLI--PVSDATLKVEWYHNNKPLKSGSRF 1626
              +Q  +      +  L + E+K+      E+ ++   ++  +   E    +  +K+ S  
Sbjct: 26491 KSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQ 26550

Query: 1627  TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLES-QHEGAL 1685
                N    + L        D             E    G++      +I   S + EG L
Sbjct: 26551 MSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGIL 26610

Query: 1686  PRLNQL-EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRV 1744
               +++  E   K Q      + ++ AP F    +   + E Q   F   +   G+P   +
Sbjct: 26611 TCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEI--SGEPSPEI 26668

Query: 1745  EWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             EW +N +PI  S+ ++        +L ++  +  DSG YT +A N  G+   +++L V
Sbjct: 26669 EWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 102/400 (25%), Positives = 157/400 (39%), Gaps = 48/400 (12%)

Query: 3546 DTLTPEAESG-NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            + ++P+ E    PP   T   D + SE   A F+CR   V+ + ++V W+   K +   S
Sbjct: 3286 EVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP-S 3341

Query: 3605 RVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILE----- 3658
            R   +  F     LEI   Y  D G YT  A+N  G+ + +  L ++  + I+ E     
Sbjct: 3342 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3401

Query: 3659 -----PQLPSHFKSGTES--------IQKLEETLHKREEITI-----EDEKPNPPRFTVE 3700
                  +  S F S  E         + K+ ETL    E  +     + EK       ++
Sbjct: 3402 IEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIK 3461

Query: 3701 IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYI 3760
               N D+  G        V  +G P  +I WF NG      +    + D    +L I + 
Sbjct: 3462 EVSNADISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFT 3519

Query: 3761 YARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAP 3820
               D GEYTC A+N +G      K  CSA   I           GE  K+ E        
Sbjct: 3520 KLEDEGEYTCMASNDYG------KTICSAYLKI--------NSKGEGHKDTETESAVAKS 3565

Query: 3821 KEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
             E+     PP F+ ++K     +     FE  V  +  P   + W++  K L +   Y  
Sbjct: 3566 LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPT--VTWFKENKQLCTSVYYTI 3623

Query: 3881 VYDM-GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            +++  G  +  +     EDSG YIC+A N  GE    A +
Sbjct: 3624 IHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 3663



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/224 (29%), Positives = 98/224 (43%), Gaps = 12/224 (5%)

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDF 4457
            E   E  ++    P+F  K    +  E + ARF+++  G P+P   W+ +   I N    
Sbjct: 1398 EETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTH 1457

Query: 4458 Q--IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
            +  I    T+S++I+      DS  +  VA+NR G +  S  L VE    Q     V P 
Sbjct: 1458 KVVIKEDGTQSLIIV-PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQ-----VKPM 1511

Query: 4516 FTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLI 4573
            F    +NVN+  G  + +  + TG    D+ WLKN   + P    KI  E   G   L I
Sbjct: 1512 FVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKI 1571

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                 QDS  Y   AIN AG  R    C V++     +P+P+ K
Sbjct: 1572 DSTVSQDSAWYTATAINKAG--RDTTRCKVNVEVEFAEPEPERK 1613



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 100/399 (25%), Positives = 173/399 (43%), Gaps = 43/399 (10%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            ++  RV E ++  F  E + E     KW+R    I +S  + I        L IR   ++
Sbjct: 6149 LKDTRVKEQQEVVFNCEVNTEGAKA-KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 6207

Query: 4477 DSAVF-AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            D A +  ++  +RG   K +ANL+VEE+  +    IV P      +++     + V    
Sbjct: 6208 DQANYNVSLTNHRGENVKSAANLIVEEEDLR----IVEP-----LKDIETMEKKSVTFWC 6258

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            KV     + + W KNG++V  D R     +   + L I +    D G+Y    I +AG+ 
Sbjct: 6259 KVNRLN-VTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEY----IVTAGQD 6313

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
            +  AE ++                 AP E +E L+D+ V E     FSC++  +    V+
Sbjct: 6314 KSVAELLI---------------IEAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVK 6357

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            WY+  + IK  K ++  +    + L I +   +DE +Y C   +   R    A+L V + 
Sbjct: 6358 WYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSR----ARLFVEEI 6413

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                 +  + P +DI+   G    F  ++ +K K  +QWLR   ++ +    QM+ EG  
Sbjct: 6414 P----VEIIRPPQDILEAPGADVVFLAEL-NKDKVEVQWLRNNMVVVQGDKHQMMSEGKI 6468

Query: 4776 AVLLIGNTYEEDTG--TFTCRATTAAGQVETSAKLVVKS 4812
              L I +    D G   F  +   A  ++E +A   +K+
Sbjct: 6469 HRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKT 6507



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 107/511 (20%), Positives = 194/511 (37%), Gaps = 37/511 (7%)

Query: 4309  VTSNTVAKSMAQRYEDNLDQT--EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQK 4366
             VT        +QR ++ + ++   E+T        + K      + S+V   +  + + +
Sbjct: 25966 VTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETR 26025

Query: 4367  QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHE 4426
             ++            K  + E   +E K+ T++      +K +       K +   V+E E
Sbjct: 26026 ESLSSYEHSASAEMKSAALEEKSLEEKSTTRK------IKTTLAARILTKPRSMTVYEGE 26079

Query: 4427  QARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAE 4486
              ARF  + DGEP+P + W R+   +  S   Q+ T   KS   I  V   D   ++ V E
Sbjct: 26080 SARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVE 26139

Query: 4487  NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
             N  G  +    L +++ R   +    PP   + +    V S + V+   +V   +P    
Sbjct: 26140 NSEGKQEAEFTLTIQKARVTEKAVTSPP--RVKSPEPRVKSPEAVKSPKRVKSPEPSHPK 26197

Query: 4547  WLKNGKKVQPDIRNKI----LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
              + +  + +P    K+    +      T  +     ++  K  CV  +S   A+   E  
Sbjct: 26198 AV-SPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK---EVT 26253

Query: 4603  VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
                   K K     +   +     E LK   + E    E+ C+I G+         G   
Sbjct: 26254 WYKDGKKLKENGHFQFHYSADGTYE-LKINNLTESDQGEYVCEISGE--------GGTSK 26304

Query: 4663  IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
                    Q  ++  E   +ISE    D+              TV  K +   P+   + P
Sbjct: 26305 TNLQFMGQAFKSIHEKVSKISETKKSDQ---------KTTESTVTRKTEPKAPEPISSKP 26355

Query: 4723  AL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              + T L+D  V     A+F  + T + +PT  W ++G  I +   +++  +     L I 
Sbjct: 26356 VIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIH 26415

Query: 4782  NTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              T   D+G +TC    +AG V +S KL +K+
Sbjct: 26416 KTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26446



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 97/434 (22%), Positives = 181/434 (41%), Gaps = 40/434 (9%)

Query: 1005  KDIIAESQHPGGLE-KIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF 1063
             ++ ++  +H    E K   LE+ S   K T  ++K T   R L   +    + EG+SA F
Sbjct: 26025 RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMT-VYEGESARF 26083

Query: 1064  EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNA 1123
                 +   +   TV W   G+ ++++ R Q          +I+SV+A D G Y+VV  N+
Sbjct: 26084 SC--DTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 26141

Query: 1124  AGEAQLSASMTVE----TRSSIDTSSIHRGLYEKTRHIE------ESKFVEPMY-QIEEI 1172
              G+ +   ++T++    T  ++ +    +    + +  E        K  EP + +    
Sbjct: 26142 EGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSP 26201

Query: 1173  SKSKPVFVQ-----PLSNPPPVSE------GKNI-HLECRLEPMGDPTMRVEWFHNGRSV 1220
             +++KP   +     P+S PP +++       K I  L C +E        V W+ +G+ +
Sbjct: 26202 TETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL 26261

Query: 1221  TVGSRFKTYYDF-GFVALDIIHATSADTGEYTVRAVNHLGSAHTS------AIVRVIERS 1273
                  F+ +Y   G   L I + T +D GEY        G++ T+      A   + E+ 
Sbjct: 26262 KENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKV 26321

Query: 1274  DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
               +++T+        +  E    R  + +    +   P     L +  TV   +V  +  
Sbjct: 26322 SKISETKKSDQ----KTTESTVTRKTEPKAPEPISSKPVIVTGLQD-TTVSSDSV-AKFA 26375

Query: 1334  LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
             ++  G+      W  +GK I  G +++ + +     L++      DSG+YTC   N  G 
Sbjct: 26376 VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGS 26435

Query: 1394  AVTSCALRVIAKKD 1407
               +SC L + A KD
Sbjct: 26436 VSSSCKLTIKAIKD 26449



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 61/214 (28%), Positives = 96/214 (44%), Gaps = 12/214 (5%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P F     N +++ G +  L   V G     + W  NG  + P    K + +   ++L+I
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA----------PP 4623
            L    +D G+Y C+A N  G+  C A   ++      K   +T++A A          PP
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK-DTETESAVAKSLEKLGGPCPP 3575

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRI 4682
              ++ LK    A+G    F   +VG+P PTV W+K +K +  S Y+ +    +   T  +
Sbjct: 3576 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 3635

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            ++   ED G Y C A N  G  T AA+L V   D
Sbjct: 3636 NDPQREDSGLYICKAENMLGESTCAAELLVLLED 3669



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 65/267 (24%), Positives = 107/267 (40%), Gaps = 7/267 (2%)

Query: 79    KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
             ++ R   G N +F   ++  PT  V W      L E +K  + Y   +G ++L I     
Sbjct: 25884 RSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSK--IHYTNTSGVLTLEILDCHT 25941

Query: 139   GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
              D G Y     N  GEA  S Y   +                 V  +V  +   T+ Y  
Sbjct: 25942 DDSGTYRAVCTNYKGEA--SDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAV 25999

Query: 199   EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDR 258
                ++T ++  ++      +     +T E     E S    +    + E  ++      R
Sbjct: 26000 SSFKKTSEMEASSSVREVKSQ--MTETRESLSSYEHSASAEMKSAALEEKSLE-EKSTTR 26056

Query: 259   SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
              +      +I  KPR+  + EG  A+F     G P P VTW + GQ L  S +H++ TT 
Sbjct: 26057 KIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK 26116

Query: 319   NHTTLRVRNTQKSDSGHYTLLAENPNG 345
               +T  + + Q SD G+Y+++ EN  G
Sbjct: 26117 YKSTFEISSVQASDEGNYSVVVENSEG 26143



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 129/538 (23%), Positives = 213/538 (39%), Gaps = 93/538 (17%)

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            ++T    +  PP+       + +     A F C +I       ++ W+   + L TG + 
Sbjct: 3182 SVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQP-KISWYKEEQLLSTGFKC 3239

Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            K ++D     L +   +  DA +YTC+A N +G AT S  L V+  + +  + ++P +  
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVY-- 3297

Query: 3667 SGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT 3726
                 I  L++T      +T E +   P RF                   CR   V    
Sbjct: 3298 -PPAIITPLQDT------VTSEGQ---PARF------------------QCR---VSGTD 3326

Query: 3727 MRIDWFHNGRPFATGSRVHTLNDF-GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +++ W+   +     SR   +  F     L+I   Y  D G YT  A+N  G  ++TA +
Sbjct: 3327 LKVSWYSKDKKIKP-SRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3385

Query: 3786 TCSAKRDIV---LESQLPQGM------------SGEKIKELERGRISDAPK---EEPIVS 3827
            +  A   I+   +E ++   M             G    EL+  +I++  +   E P+ S
Sbjct: 3386 SLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYS 3445

Query: 3828 TP---------PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878
            T          P FI ++ +  +  S G      V     PK +I+W+ NG LL     Y
Sbjct: 3446 TKFDSEKEGTGPIFIKEVSNADI--SMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADY 3503

Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938
            + V+D    SL IL+   ED GEY C A ND+G+    A +           N    G K
Sbjct: 3504 KFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI---------NSKGEGHK 3554

Query: 3939 RSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLA 3998
             +E  + +  +++K                   PP F+ +++       +    FE  + 
Sbjct: 3555 DTETESAVAKSLEKLGGPC--------------PPHFLKELKPIRCAQGLPAI-FEYTV- 3598

Query: 3999 PVGDPNMKVEWFFNGKPLLHKNRFTPIYD-FGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             VG+P   V WF   K L     +T I++  G           EDSG Y+C+A N+ G
Sbjct: 3599 -VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG 3655



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 79/297 (26%), Positives = 132/297 (44%), Gaps = 23/297 (7%)

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITV-MQAPQFSRALHNIETVEGTNVHLECR 1333
            I   T  E+  E +   E     T +V   + + +  P     L N+  +EG +V LEC 
Sbjct: 860  ITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECH 919

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            +   G  +  V W+     I++   F+  ++     L +   + EDSG +TC A N+ G 
Sbjct: 920  IS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGT 977

Query: 1394 AVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII--DESVT---------I 1442
              TSC L V   ++   E +  +  EK    E+    +  D++  D S+T          
Sbjct: 978  VSTSCYLAVQVSEE--FEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLTEEQAGPGEPA 1034

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD--FG 1500
             P F+T+P  ++ ++EG  V F C++    +    V W K+G P+T G+R++  ++   G
Sbjct: 1035 APYFITKP-VVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1091

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
               L I    A+D+G YT    N  G    S  L   +  +++  +Q E  L Q QV
Sbjct: 1092 ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEM-LYQTQV 1147



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 156/764 (20%), Positives = 276/764 (36%), Gaps = 64/764 (8%)

Query: 4058  ETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLP 4117
             E K+ +  T +    Y+      MKS   + E     + T  ++     AR     ++ P
Sbjct: 26016 EVKSQMTETRESLSSYEHSASAEMKSAA-LEEKSLEEKSTTRKIKTTLAAR----ILTKP 26070

Query: 4118  DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYD 4176
              ++TV EGE ARF C   G P P V WL  G  +   +R+++T       F+I   +  D
Sbjct: 26071 RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASD 26130

Query: 4177  TGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFE 4236
              G   V+             L +       + V  + PR    E         +  K  +
Sbjct: 26131 EGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVT-SPPRVKSPEPRVKSPEAVKSPKRVK 26189

Query: 4237  ERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLR 4296
               +         H   + P   K   TE  Q +      +    L+   ++++ K + + 
Sbjct: 26190 SPEP-------SHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVV 26242

Query: 4297  ESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVH 4356
             ES+    +   +VT     K + +        + + T +     +T+  +     E +  
Sbjct: 26243 ESS---VLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGE 26299

Query: 4357  G--KEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE--GPVKPSKPPI 4412
             G   + ++    Q  K +    E   KI+ T+ ++ +    T  R  E   P   S  P+
Sbjct: 26300 GGTSKTNLQFMGQAFKSI---HEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV 26356

Query: 4413  FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
                 +Q   V     A+F V+  GEP P   W ++   I     +++        L I +
Sbjct: 26357 IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 26416

Query: 4473  VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
                 DS ++    +N                      G V  S  LT + +  T  Q   
Sbjct: 26417 TDTSDSGLYTCTVKNSA--------------------GSVSSSCKLTIKAIKDTEAQ--- 26453

Query: 4533  LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD--SGKYECVAIN 4590
                KV+  K  ++   K    VQ +I  K L  +    + + EA  Q+  + K E   + 
Sbjct: 26454 ---KVSTQKTSEITPQKKAV-VQEEISQKALRSE---EIKMSEAKSQEKLALKEEASKVL 26506

Query: 4591  SAGEARCDAECVVSLPATKD---KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              + E +  A   +      +   K    ++      EI        + EGQ +     I 
Sbjct: 26507 ISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIA 26566

Query: 4648  GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             G     V+W      +  S+ ++   +  + TL I +A   DEG   C++    G   V 
Sbjct: 26567 GAT--DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEG--IVK 26622

Query: 4708  AKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
              +  +T   +  + PA ++  R   + EGQ   F  +I+ +  P I+W +    I  + +
Sbjct: 26623 CQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN 26682

Query: 4767  FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
               +    N   L I N    D+G +T +A    GQ   +A L+V
Sbjct: 26683 VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 99/428 (23%), Positives = 170/428 (39%), Gaps = 35/428 (8%)

Query: 1803  QSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSA 1862
             +++ SL       SA  K   LE+ S  ++    ++    A R +T+    T + EG+SA
Sbjct: 26023 ETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMT-VYEGESA 26081

Query: 1863  HYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAI 1922
              + C  +  P P   V W   G+VL +  R++ +     +  +I +V   D G Y+    
Sbjct: 26082 RFSCDTDGEPVPT--VTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVE 26139

Query: 1923  NNLGQAVSSIRLNVQSKE-------SIIRDSQHESALEKIQYLEDDSRYK-------RAV 1968
             N+ G+  +   L +Q          S  R    E  ++  + ++   R K       +AV
Sbjct: 26140 NSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAV 26199

Query: 1969  ---QDDSFVVEKPQF---GKPIKNAEVTEGHPVHLEATLTPVNDPTM----RVEWYCNGR 2018
                +      EK Q      P K  +  +       A LT V + ++     V WY +G+
Sbjct: 26200 SPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGK 26259

Query: 2019  PVQQGHRFKTTYDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLY- 2076
              +++   F+  Y   G   L I      D G Y+C+ +   G + T       A   ++ 
Sbjct: 26260 KLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHE 26319

Query: 2077  -LDTLDEQRL--KKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRV 2133
              +  + E +   +K  E     + +P   E    +PV +T L     +     A F   V
Sbjct: 26320 KVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT-TVSSDSVAKFA--V 26376

Query: 2134  EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
             +   +P  T  W  +G+ I  G +Y+ + D G   L+I  T   DSG Y C   N  G  
Sbjct: 26377 KATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSV 26436

Query: 2194  VNTCTLKV 2201
              ++C L +
Sbjct: 26437 SSSCKLTI 26444



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 77/263 (29%), Positives = 112/263 (42%), Gaps = 19/263 (7%)

Query: 1699 RHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            R  A  E+    P     +K++ V E ++   E  +   G P   V W R    IE+S  
Sbjct: 885  RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSID 942

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
                   G   L ++    EDSG +TC A+NE G   TS  L VQ   S + E +  +  
Sbjct: 943  FQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--VSEEFEKETTAVT 1000

Query: 1819 QKIQQLED---SSRYQRREDVEVAVNQ-------APRFITQLNGPTKLSEGQSAHYECRI 1868
            +K    E     SR     D  +   Q       AP FIT+     KL EG S  + C++
Sbjct: 1001 EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQV 1059

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTS--NDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
               P P+  V W  +G  L +G+RY+ S     G   L I   + +D+GEYT    N  G
Sbjct: 1060 GGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1117

Query: 1927 QAVSSIRLNVQSKESIIRDSQHE 1949
            +  +S  L  ++   ++  SQ E
Sbjct: 1118 ETSASASLLEEADYELLMKSQQE 1140



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 91/384 (23%), Positives = 165/384 (42%), Gaps = 44/384 (11%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            + +    V E E ARFE E   + +    W  +   +  +PD +I        L++    
Sbjct: 5614 RPLHSVEVMETETARFETEISEDDIHA-NWKLKGEALLQTPDCEIKEEGKIHSLVLHNCR 5672

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            ++ +      A N     K SA+L V+ +      G++ P      ++V VT+G+    D
Sbjct: 5673 LDQTGGVDFQAAN----VKSSAHLRVKPRVI----GLLRP-----LKDVTVTAGETATFD 5719

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +++  + I V W   GKK++P  +     E   +TL + +   +D+G+ +     +A +
Sbjct: 5720 CELS-YEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQL----TAKD 5774

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V  P               P E  +PL+D+ V EG      C+ V +    V
Sbjct: 5775 FKTHANLFVKEP---------------PVEFTKPLEDQTVEEGATAVLECE-VSRENAKV 5818

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W+K    I  SK +++        L I +  PED   Y C A +       +  L V  
Sbjct: 5819 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKD----FKTSCNLNVVP 5874

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
            P    ++  L PL D+ V E + A+F+ ++ S+    ++W ++GA I +   + +I +G 
Sbjct: 5875 P----HVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGA 5929

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTA 4798
              +L+I     +D   ++C   TA
Sbjct: 5930 VRILVINKCLLDDEAEYSCEVRTA 5953



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 156/721 (21%), Positives = 268/721 (37%), Gaps = 85/721 (11%)

Query: 3534  KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEW 3593
             K AALE  S    + T + ++       T P  + + E  SA F C      +    V W
Sbjct: 26040 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTD--GEPVPTVTW 26097

Query: 3594  FHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV-KGR 3652
                G+ L T +R +          EI  V   D G Y+    N  G+      L + K R
Sbjct: 26098 LRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26157

Query: 3653  ---QGIILEPQL--PSHFKSGTESIQ-----KLEETLHKREEITIEDEKPNP-------- 3694
                + +   P++  P       E+++     K  E  H +  ++  + KP P        
Sbjct: 26158 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKA-VSPTETKPTPTEKVQHLP 26216

Query: 3695  ----PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLN 3748
                 P+ T  +K              C VE        + W+ +G+        + H   
Sbjct: 26217 VSAPPKITQFLKAEASKEIA---KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSA 26273

Query: 3749  DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE-SQLPQGM-SGE 3806
             D G   L I+ +   D GEY C  + + G++ T  +    A + I  + S++ +   S +
Sbjct: 26274 D-GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQ 26332

Query: 3807  KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866
             K  E    R ++    EPI S+ P  +T ++  TV      +F   V+   +P+    W 
Sbjct: 26333 KTTESTVTRKTEPKAPEPI-SSKPVIVTGLQDTTVSSDSVAKFA--VKATGEPRPTAIWT 26389

Query: 3867  RNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG-------------ED 3913
             ++GK +  G +Y+   D G   L+I      DSG Y C   N  G             +D
Sbjct: 26390 KDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26449

Query: 3914  FTKATISCKKLPDI------ILQNQVPRG------MKRSEALTQMEATIKKYTSEVYLTE 3961
                  +S +K  +I      ++Q ++ +       +K SEA +Q +  +K+  S+V ++E
Sbjct: 26450 TEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISE 26509

Query: 3962  DDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR 4021
             +             V +  ++TS    E  +   ++       M +     G+ L+ K  
Sbjct: 26510 EVKKSAATSLEKSIVHEEITKTSQAS-EEVRTHAEIKAFST-QMSIN---EGQRLVLKAN 26564

Query: 4022  FTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHM 4081
                  D  +V      V   +S EY      + G D+T  + + + +     D  +   +
Sbjct: 26565 IAGATDVKWV---LNGVELTNSEEY---RYGVSGSDQTLTIKQASHR-----DEGI---L 26610

Query: 4082  KSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPR 4141
               I K +E     Q       E S A   P F+S P +  + EG+   F C ++G P P 
Sbjct: 26611 TCISKTKEGIVKCQYDLTLSKELSDA---PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26667

Query: 4142  VMWLLNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVI 4200
             + W  N   I   S   ++    +Y  +I      D+GK  +              L V+
Sbjct: 26668 IEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727

Query: 4201  P 4201
             P
Sbjct: 26728 P 26728



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 116/517 (22%), Positives = 208/517 (40%), Gaps = 48/517 (9%)

Query: 4307 DKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQK 4366
            D+    T  K + +         E+V E+  + +   K R  +     +   E+   K+ 
Sbjct: 1919 DRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKD 1978

Query: 4367 QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPV-KPSK---------PPIFTKK 4416
            ++ +E++   +      + E TE E KA  +E  +  P  KP K         P IF ++
Sbjct: 1979 ESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIF-ER 2037

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSILIIRQVFV 4475
            +Q   V +   A F V   G+P P  +WY+    I+ S   +          L+IR V  
Sbjct: 2038 IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTA 2097

Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            EDSA     A N  G     A L+V+ K+      ++  +FT   Q+V       +    
Sbjct: 2098 EDSASIMVKAINIAGETSSHAFLLVQAKQ------LI--TFTQELQDVVAKEKDTMATFE 2149

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T    + V W K+G +V    + ++  +   + L IL     D+  Y CV +      
Sbjct: 2150 CETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NV 2208

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
            +  A+ +V                 A  E ++ L+D  V E  + E  C IV       +
Sbjct: 2209 KTTAKLIVE---------------GAVVEFVKELQDIEVPESYSGELEC-IVSPENIEGK 2252

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            WY  D  +K +  + ++       L + +   ED+G+Y  V      + T   K+K  +P
Sbjct: 2253 WYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMK-PRP 2309

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                 +  L  L D  V EG   Q + +++ +    + W+++G  +  +    ++ +  +
Sbjct: 2310 -----IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQS 2363

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +LLI +  +ED G ++   T  A  + TS ++ V S
Sbjct: 2364 HMLLIEDMTKEDAGNYS--FTIPALGLSTSGRVSVYS 2398



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 73/261 (27%), Positives = 114/261 (43%), Gaps = 14/261 (5%)

Query: 3803 MSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            + G + K  E  R+  AP E P+  TPP  ++ +K+ TV E E V  EC +     P   
Sbjct: 873  LHGREAKVTETARVP-APVEIPV--TPPTLVSGLKNVTVIEGESVTLECHISGYPSPT-- 927

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            + WYR    + S   ++  +  G   L I   +AEDSG + C AVN+ G   T   ++ +
Sbjct: 928  VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987

Query: 3923 KLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQ 3982
               +   +         +E    +E+     T +  LTE+      +   P F+T+   Q
Sbjct: 988  VSEEFEKETTAVTEKFTTEEKRFVESRDVVMT-DTSLTEEQA-GPGEPAAPYFITKPVVQ 1045

Query: 3983 TSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD--FGYVAMNFGWVYP 4040
              LVE  +  F CQ+   G+P   V W  +G PL    R+   Y+   G   +     + 
Sbjct: 1046 -KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFA 1102

Query: 4041 EDSGEYLCRATNLYGMDETKA 4061
            +D+GEY     N +G  ET A
Sbjct: 1103 DDAGEYTIVVRNKHG--ETSA 1121



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 151/731 (20%), Positives = 278/731 (38%), Gaps = 78/731 (10%)

Query: 1529  EVSCRLTCRSTTDIVRSTQNEAGLE-QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNV 1587
             EV  ++T   T + + S ++ A  E +   LE++S   ++      TT A    T  +++
Sbjct: 26016 EVKSQMT--ETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSM 26073

Query: 1588  EIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDS 1647
              + EG+ A F        +    V W    + L + +R   T        +I S    D 
Sbjct: 26074 TVYEGESARFS--CDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDE 26131

Query: 1648  GTYTCRAINALGEAVTSGIAIVH----SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQ 1703
             G Y+    N+ G+        +     ++K++    + +   PR+   E     +R  + 
Sbjct: 26132 GNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSP 26191

Query: 1704  D-----------------EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL---- 1742
             +                 E +   PV + P K  +  + +A+   A+L  V +  +    
Sbjct: 26192 EPSHPKAVSPTETKPTPTEKVQHLPV-SAPPKITQFLKAEASKEIAKLTCVVESSVLRAK 26250

Query: 1743  RVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
              V W ++G  ++ +      +   G   L +  +   D G Y C    E G + T+    
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26310

Query: 1802  VQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVA--VNQAPRFITQLNGPTKLSEG 1859
              Q+  S+  +    S  +K  Q    S   R+ + +    ++  P  +T L   T +S  
Sbjct: 26311 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSSD 26369

Query: 1860  QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
               A +  +    P P     W  +GK +  G +Y+ S D G   L+I      DSG YTC
Sbjct: 26370 SVAKFAVKATGEPRPT--AIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 26427

Query: 1920  KAINNLGQAVSSIRLNVQS--------------------KESIIRDSQHESAL--EKIQY 1957
                N+ G   SS +L +++                    K++++++   + AL  E+I+ 
Sbjct: 26428 TVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKM 26487

Query: 1958  LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVT--EGHPVHLEATLTPVNDPTMR----V 2011
              E  S+ K A+++++    K    + +K +  T  E   VH E T T      +R    +
Sbjct: 26488 SEAKSQEKLALKEEA---SKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEI 26544

Query: 2012  EWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
             + +     + +G R     +    A D+ +      G  +   +      V+ S   +  
Sbjct: 26545 KAFSTQMSINEGQRLVLKANIA-GATDVKWVL---NGVELTN-SEEYRYGVSGSDQTLTI 26599

Query: 2072  KSGLYLDTLDEQRLKKIQE-LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFE 2130
             K   + D      + K +E + K +    + +E     P F++   S +N+ EG    F 
Sbjct: 26600 KQASHRDEGILTCISKTKEGIVKCQYDLTLSKEL-SDAPAFISQPRS-QNINEGQNVLFT 26657

Query: 2131  CRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKL 2190
             C +    +P   I+WF N   I        +      +L+I      DSG Y  KA N  
Sbjct: 26658 CEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFR 26715

Query: 2191  GEAVNTCTLKV 2201
             G+   T +L V
Sbjct: 26716 GQCSATASLMV 26726



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 22/283 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            VE+ V   P  ++ L   T + EG+S   EC I  YP P   V WY     ++S   ++ 
Sbjct: 890  VEIPVTP-PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQI 945

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            +   G A L I   + EDSG +TC A+N  G   +S  L VQ  E    + +  +  EK 
Sbjct: 946  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF--EKETTAVTEK- 1002

Query: 1956 QYLEDDSRYKRA----VQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPV------N 2005
             +  ++ R+  +    + D S   E+   G+P     +T+     L    + V       
Sbjct: 1003 -FTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1061

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYD--FGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            +P   V W  +G P+  G+R+K +Y+   G   L I   +A+D G Y     N  GE   
Sbjct: 1062 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSA 1121

Query: 2064 TSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPG 2106
            ++S+  +A   L + +  ++ L + Q     + PK + E  PG
Sbjct: 1122 SASLLEEADYELLMKS-QQEMLYQTQVTAFVQEPK-VGETAPG 1162



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 89/379 (23%), Positives = 159/379 (41%), Gaps = 28/379 (7%)

Query: 4360 VHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQP 4419
            V V+++ + +   V +K  T +    E+ ++     +      GP +P+ P   TK +  
Sbjct: 986  VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQ 1045

Query: 4420 CRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSILIIRQVFVED 4477
             ++ E     F  +  G P P + W +   P+     +++  +  + +  L+I   F +D
Sbjct: 1046 -KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADD 1104

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            +  +  V  N+ G    SA+L+ E         ++  S         VT+   V+ + KV
Sbjct: 1105 AGEYTIVVRNKHGETSASASLLEEADYE-----LLMKSQQEMLYQTQVTA--FVQ-EPKV 1156

Query: 4538 TGTKPIDVY--WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T P  VY  + K  +K Q  IR K+ ++      +++  Y +D  ++   +       
Sbjct: 1157 GETAPGFVYSEYEKEYEKEQALIRKKMAKDT-----VVVRTYVEDQ-EFHISSFEERLIK 1210

Query: 4596 RCDAECV-VSLPATKDKPKPQTKAAN-APPEIIEP-----LKDKIVAEGQAIEFSCKIVG 4648
              +   +  +L    ++   +  A + +  E +E      +K+  + EG  + F CK+ G
Sbjct: 1211 EIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSG 1270

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             PLP + WYK  K IK  + +QM    D   +LRI    PEDEG Y   A N  G    +
Sbjct: 1271 YPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICS 1330

Query: 4708 AKLKVTQPDQADNLPALTP 4726
             KL V +P      P   P
Sbjct: 1331 GKLYV-EPAAPLGAPTYIP 1348



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 59/199 (29%), Positives = 85/199 (42%), Gaps = 5/199 (2%)

Query: 4409  KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSI 4467
             +PP FT  +     +  E  RF V     P P + WY+    IK   + + +TF S K +
Sbjct: 25191 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGL 25250

Query: 4468  --LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
               L I  V  +D A +  VA N+ G   C A L V           + P F     N   
Sbjct: 25251 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-TLHPPPTDSTLRPMFKRLLANAEC 25309

Query: 4526  TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKY 4584
               GQ V  + +V+G  P  + W K+G+ +      +I+ E    Y L I +  P+D+G Y
Sbjct: 25310 QEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25369

Query: 4585  ECVAINSAGEARCDAECVV 4603
                A N+AG   C A   V
Sbjct: 25370 RVTATNTAGSTSCQAHLQV 25388



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 138/665 (20%), Positives = 250/665 (37%), Gaps = 59/665 (8%)

Query: 784   EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
             EG +A F        +P   V W + G+ ++ S+R          +  I  ++A D G+Y
Sbjct: 26077 EGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 26134

Query: 844   TVRAVNKLG--EAISTASIRVA--ARSTVTADLGI--PEQRRYIEKTXXXXXXXXXXXXX 897
             +V   N  G  EA  T +I+ A      VT+   +  PE R    +              
Sbjct: 26135 SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPS 26194

Query: 898   XXXXVPESTQKPEFKTPIKD-QISI--KEGGFAHFEARLE------PIGDSTLR---VEW 945
                 V  +  KP     ++   +S   K   F   EA  E       +  S LR   V W
Sbjct: 26195 HPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTW 26254

Query: 946   LKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
              KDG+ ++ +      ++  G   L I ++T  D G Y C      G + T+        
Sbjct: 26255 YKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAF 26314

Query: 1005  KDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK--ITQKPRFLGPLKGTNKIVEGQSAH 1062
             K I  +       +K       S  +++TE +    I+ KP  +  L+ T  +     A 
Sbjct: 26315 KSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSSDSVAK 26373

Query: 1063  FEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
             F   V+   +   T  W  +GK IT   + +   D G   L+I      DSG+YT   +N
Sbjct: 26374 FA--VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKN 26431

Query: 1123  AAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQI-EEISKSKPVFVQ 1181
             +AG    S  +T++     +   +     +KT  I   K      +I ++  +S+ + + 
Sbjct: 26432 SAGSVSSSCKLTIKAIKDTEAQKVST---QKTSEITPQKKAVVQEEISQKALRSEEIKMS 26488

Query: 1182  PLSNPPPVS---EGKNIHLECRLEPMGDPTMRVEWFHNGRSVT--VGSRFKTYYDFGFVA 1236
                +   ++   E   + +   ++     ++     H   + T       +T+ +    +
Sbjct: 26489 EAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS 26548

Query: 1237  LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
               +    S + G+  V   N  G+     ++  +E ++           +Q   ++ A+ 
Sbjct: 26549 TQM----SINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASH 26604

Query: 1297  R----------TKQ----VREDITVMQ----APQFSRALHNIETVEGTNVHLECRLQPVG 1338
             R          TK+     + D+T+ +    AP F     +    EG NV   C +   G
Sbjct: 26605 RDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEIS--G 26662

Query: 1339  DQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSC 1398
             + +  +EWF N  PI        +   +  +L++ +    DSG YT +A N  G+   + 
Sbjct: 26663 EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 26722

Query: 1399  ALRVI 1403
             +L V+
Sbjct: 26723 SLMVL 26727



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 67/227 (29%), Positives = 98/227 (43%), Gaps = 7/227 (3%)

Query: 4315 AKSMAQRYEDNLDQ-TEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVV 4373
            A S AQ+   ++   T + +E RV+ + T  P+ P       +  E  V  +K+    + 
Sbjct: 802  ATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSIT 861

Query: 4374 GDKEITRKITSTETTEIEHKAQTQERVVEGPVK-PSKPPIFTKKMQPCRVFEHEQARFEV 4432
            G    T +    E         T+   V  PV+ P  PP     ++   V E E    E 
Sbjct: 862  GT---TVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
               G P P + WYRE++ I++S DFQI   S  + L+IR+ F EDS  F   A N  GT 
Sbjct: 919  HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 978

Query: 4493 KCSANLVVE-EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
              S  L V+  +  +     V   FT T +   V S  +V  DT +T
Sbjct: 979  STSCYLAVQVSEEFEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLT 1024



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 130/523 (24%), Positives = 202/523 (38%), Gaps = 72/523 (13%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PPQ +  L+ VT   G    F   I   G P  KI W K  Q +    +   +      +
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3249

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L ++    +D+  YTC A +  GVA T A L V          + PE +   Q++  Y  
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQEMPVYP- 3298

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                          P  I PLQD     EG+ A F+ +   VS   ++V WY   + I  
Sbjct: 3299 --------------PAIITPLQDT-VTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 3340

Query: 816  SS--RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV---TA 870
            S   R+T  F   Y  L I     ED G+YT  A N +G+  STA++ + A  ++     
Sbjct: 3341 SRFFRMTQ-FEDTY-QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERI 3398

Query: 871  DLGIP-EQRRYIEKTXXXXXXXXXXXXXXXXXVPES----TQKPEFKTPIKDQ------I 919
            +  I  E + +                     + E+    ++ P + T    +      I
Sbjct: 3399 EQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPI 3458

Query: 920  SIKEGGFAHFE------ARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKS 973
             IKE   A           +  IG    +++W  +G  +  S+     F+    +L I  
Sbjct: 3459 FIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF 3518

Query: 974  VTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRT 1033
              + D G YTC A N  G+   SA L I +K +   +++    + K             +
Sbjct: 3519 TKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK-------------S 3565

Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI-TSANRI 1092
             E++     P FL  LK   +  +G  A FE  V    +   TV W+   KQ+ TS    
Sbjct: 3566 LEKLGGPCPPHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYT 3622

Query: 1093 QTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              ++  G     +   + EDSG+Y   A N  GE+  +A + V
Sbjct: 3623 IIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 97/427 (22%), Positives = 171/427 (40%), Gaps = 49/427 (11%)

Query: 4387 TTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T E+  +A   +      VK   P IF   +   +VFE ++A+FE E   EP    +W +
Sbjct: 5320 TGEVSFQAANAKSAANLKVK-ELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLK 5377

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
                I     F++    TK  ++I+    ED A +   AE++  + K    L++E  R +
Sbjct: 5378 GTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGK----LIIEGIRLK 5433

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
                     F    ++V     +      +++    I V W KN +++       + +E 
Sbjct: 5434 ---------FLTPLKDVTAKEKESAVFTVELSHDN-IRVKWFKNDQRLHTTRSVSMQDEG 5483

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
             T+++   +    D+ +    A+  + EA+                          P   
Sbjct: 5484 KTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTV-------------------LEGDPYFT 5524

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              L+D    E   +   C+I     P V+W+K  K IKPSK   +     +  L + +A 
Sbjct: 5525 GKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKAL 5583

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
              D G Y C      G    + KL +   +    +  + PL  + V E + A+F+T+I S
Sbjct: 5584 KSDIGQYTC----DCGTDKTSGKLDIEDRE----IKLVRPLHSVEVMETETARFETEI-S 5634

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
            +      W  +G  + +TPD ++  EG    L++ N   + TG    +    A  V++SA
Sbjct: 5635 EDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQ----AANVKSSA 5690

Query: 4807 KLVVKSK 4813
             L VK +
Sbjct: 5691 HLRVKPR 5697



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 101/479 (21%), Positives = 194/479 (40%), Gaps = 41/479 (8%)

Query: 2243  RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
             R +T+ R  T V+EG++A F C  +   +P   + +   G+ L ++AR  +T      + 
Sbjct: 26065 RILTKPRSMT-VYEGESARFSCDTDG--EPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF 26121

Query: 2303  DIQHCVPEDAGEYSVKAINALGHCTSAISMT----------VTAKGSIISESQR---PEG 2349
             +I      D G YSV   N+ G   +  ++T          VT+   + S   R   PE 
Sbjct: 26122 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 26181

Query: 2350  LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQN--------IDNIQEGQTAHFDCRLI 2401
             ++  + ++S EP   P+   P T  +P  T+ +Q+        I    + + +    +L 
Sbjct: 26182 VKSPKRVKSPEP-SHPKAVSP-TETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLT 26239

Query: 2402  PVGDPTL----KVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNL 2456
              V + ++    +V W+++ K ++++      +   G   + I+++ + D+G Y+C  S  
Sbjct: 26240 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGE 26299

Query: 2457  LGEXXXXXXXXXXXXXXIQLETQH-PEGMKKIQKLEQPHERRSEEPDREFEKPIFTQ--V 2513
              G               I  +     E  K  QK  +    R  EP  +  +PI ++  +
Sbjct: 26300 GGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP--KAPEPISSKPVI 26357

Query: 2514  LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSV 2573
             +TG  +      +  +  V   G+P     W  +G  +  G +++ + D G   L+I+  
Sbjct: 26358 VTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKT 26417

Query: 2574  VANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMF 2633
               +D+GLY C   N AG                  Q +  +   +I  ++ A+  V E  
Sbjct: 26418 DTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAV--VQEEI 26475

Query: 2634  VDTGVQQAPIFTTHLKSYDKLV---EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA 2689
                 ++   I  +  KS +KL    E   V +  +V+     +L+       +T T+ A
Sbjct: 26476 SQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQA 26534



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 95/417 (22%), Positives = 164/417 (39%), Gaps = 45/417 (10%)

Query: 70    SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
             S P+     ++   +    AKF  K  G P P   WT+    + +  KY +  +E  G  
Sbjct: 26353 SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL--SEDKGGF 26410

Query: 130   SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
              L I +    D G YTCT +N  G    S  +  +               +  SE    K
Sbjct: 26411 FLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVST---QKTSEITPQK 26467

Query: 190   AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREV--SFRESITKRYVGE 247
                 Q   ++++ +++++  +           K +  +  +  EV  S   S+ K  V E
Sbjct: 26468 KAVVQEEISQKALRSEEIKMSEAKSQEKLA-LKEEASKVLISEEVKKSAATSLEKSIVHE 26526

Query: 248   SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307
                +I+     S    +  +I        + EG     +  ++G     V W  NG  L 
Sbjct: 26527 ---EITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVELT 26581

Query: 308   NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
             NS ++    + +  TL ++     D G  T        CI         S T+  +   +
Sbjct: 26582 NSEEYRYGVSGSDQTLTIKQASHRDEGILT--------CI---------SKTKEGIV--K 26622

Query: 368   SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
              QY     +       E+S+   AP F+   + +++ EG+   F C ++G P PE+ WF 
Sbjct: 26623 CQYDLTLSK-------ELSD---APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK 26672

Query: 428   NDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             N+  I    N  + ++ S N ++L I N ++SDSG  T  A+N  G+ +    L V+
Sbjct: 26673 NNLPISISSN--VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 71/236 (30%), Positives = 106/236 (44%), Gaps = 17/236 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP  +  LK+VT +EG  +  E  I   G P+  + W +    IE+S  F   F+ G   
Sbjct: 896  PPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIAR 953

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIER-TSQHPE--TLQYIQQLED 752
            L +     +DSG +TC AV+  G   T   L V      E+ T+   E  T +  + +E 
Sbjct: 954  LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013

Query: 753  YSKYQHQESIEEQTS-----QRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
                    S+ E+ +       P FI +P+  + +L EG +  F  Q+    +P   V W
Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVEGGSVVFGCQVG--GNPKPHVYW 1069

Query: 807  YKDGRPITASSRITSIFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
             K G P+T   R    +N   G   L I    A+DAG YT+   NK GE  ++AS+
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 56/208 (26%), Positives = 92/208 (44%), Gaps = 11/208 (5%)

Query: 371   ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430
             IT T Q   E R     KA + Q         + EG+       + G    +V W +N  
Sbjct: 26528 ITKTSQASEEVRTHAEIKAFSTQM-------SINEGQRLVLKANIAGAT--DVKWVLNGV 26578

Query: 431   QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490
             ++ +   ++  V+ S +  L I   +  D G++TC+++ K G    Q  L  + KE   A
Sbjct: 26579 ELTNSEEYRYGVSGS-DQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDA 26636

Query: 491   PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
             P F+ +  + N+ EG+ V+      G P+P I W K+ +PI  +  + I       +L+I
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26696

Query: 551   PRAKASDAAWYQCTAQNVAGSTATRARL 578
               A  SD+  Y   A+N  G  +  A L
Sbjct: 26697 RNASVSDSGKYTIKAKNFRGQCSATASL 26724



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 52/206 (25%), Positives = 97/206 (47%), Gaps = 4/206 (1%)

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSK 4667
            ++  + Q +    P  +++P+  K + EGQ   F  K+VG+P+P   W+  G +++    
Sbjct: 1398 EETDESQLERLYKPVFVLKPVSFKCL-EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYT 1456

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +  + +     +L I  A P D G++  VA N AGR +++  L V   +       +  L
Sbjct: 1457 HKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKL 1516

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI--PETPDFQMIHEGNNAVLLIGNTYE 4785
            +++ + EG   + K + T    P I WL+   +I   + P  ++      A L I +T  
Sbjct: 1517 KNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVS 1576

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            +D+  +T  A   AG+  T  K+ V+
Sbjct: 1577 QDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 87/347 (25%), Positives = 143/347 (41%), Gaps = 29/347 (8%)

Query: 242  KRYVGESDVQIS-TEI-DRSLGPVSP--PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
            KR+V   DV ++ T + +   GP  P  P    KP   KL EG    F  Q+ GNP+P V
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067

Query: 298  TWFKNGQRLINSNKHEIITTHNHTT----LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
             W K+G  L    ++++  ++N  T    L +  T   D+G YT++  N +G    S  L
Sbjct: 1068 YWKKSGVPLTTGYRYKV--SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125

Query: 354  AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
              E+  E  ++ Q+ + +  TQ     +  ++ E   AP FV    +++    K      
Sbjct: 1126 LEEADYELLMKSQQ-EMLYQTQVTAFVQEPKVGE--TAPGFVYSEYEKEYE--KEQALIR 1180

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
            +   +    V  ++ D++       + L+ E       I   TL +          + GE
Sbjct: 1181 KKMAKDTVVVRTYVEDQEFHISSFEERLIKEI---EYRIIKTTLEE-------LLEEDGE 1230

Query: 474  TAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
               +  +++ E E  V   F  R     + EG  V  + +  G P P+I W KDG  I  
Sbjct: 1231 E--KMAVDISESE-AVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKH 1287

Query: 534  NPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
                ++     G ++L IP     D   Y   A N+ G+     +LY
Sbjct: 1288 GERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLY 1334



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 80/316 (25%), Positives = 131/316 (41%), Gaps = 17/316 (5%)

Query: 179   YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE 238
             Y  V E  E K       T +++R T+K A T+     S +         +  + V   E
Sbjct: 26134 YSVVVENSEGKQEAEFTLTIQKARVTEK-AVTSPPRVKSPEPRVKSPEAVKSPKRVKSPE 26192

Query: 239   SITKRYVGESDVQIS-TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
                 + V  ++ + + TE  + L   +PPKI Q  +    +E A     V+ S      V
Sbjct: 26193 PSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEV 26252

Query: 298   TWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVT------- 349
             TW+K+G++L  +   +   + + T  L++ N  +SD G Y        G   T       
Sbjct: 26253 TWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQ 26312

Query: 350   ---SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
                S +  V   +E+   DQ++   T T++ E +    IS K   P  V   QD  V+  
Sbjct: 26313 AFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSK---PVIVTGLQDTTVSSD 26369

Query: 407   KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
              + +F  + TG P P   W  + + I     +K L  + G   L I     SDSG+ TC 
Sbjct: 26370 SVAKFAVKATGEPRPTAIWTKDGKAITQGGKYK-LSEDKGGFFLEIHKTDTSDSGLYTCT 26428

Query: 467   ARNKSGETAFQCRLNV 482
              +N +G  +  C+L +
Sbjct: 26429 VKNSAGSVSSSCKLTI 26444



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 23/262 (8%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP++ Q+ +   +Q G  A+F   +SG P+P+++W+K  Q L    K + +      TL 
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +      D+  YT  A+N  G   TS  L+VE P E    DQ                  
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP-EVVSPDQEM---------------- 3294

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P  +   QD   +EG+  RF CRV+G    +V+W+  D++I+     ++   E
Sbjct: 3295 ---PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
               + L I      D G  T VA N  G+ +    L++   E ++  + +E+   + ++E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHER-IEQEIEMEMKE 3408

Query: 505  GEPVVLNARAVGTPTPRITWQK 526
                 L+A   G  +  +   K
Sbjct: 3409 FSSSFLSAEEEGLHSAELQLSK 3430



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 100/385 (25%), Positives = 155/385 (40%), Gaps = 60/385 (15%)

Query: 2904 PDTEYPK-PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            PD E P  P  II    +    EGQ    + +V   +  DLK+ WY   K ++    F++
Sbjct: 3290 PDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRM 3346

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLI-ERTQHP----- 3016
            T       L++ + Y  D G YT  A N  G+  +++ +   + ++++ ER +       
Sbjct: 3347 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEM 3406

Query: 3017 ---------KGTEGLE-------KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI--V 3058
                        EGL        KI    + L + P      D+ +        K++   
Sbjct: 3407 KEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNA 3466

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            DIS G +A    ++I  G     I+WF+NG  +  S   + V+      L IL TK  D 
Sbjct: 3467 DISMGDVATLSVTVI--GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDE 3524

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQK--------------------PRFTTHIQNI 3158
            G Y+C A+N +G+   S  L+   K +G K                    P F   ++ I
Sbjct: 3525 GEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPI 3584

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS---TRIKTVSDFG-FVVLDIAYT 3214
                 G  A FE TV  V +P   + W+   + +  S   T I   +  G F+V D    
Sbjct: 3585 R-CAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVND---P 3638

Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATI 3239
            Q  DSG Y+C+A N  GE    A +
Sbjct: 3639 QREDSGLYICKAENMLGESTCAAEL 3663



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 82/333 (24%), Positives = 143/333 (42%), Gaps = 40/333 (12%)

Query: 2924  VEGQVLHLEGQ--------VEPKN-DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLV 2974
             V GQ++H  G+         + +N D   ++ WYF  + LE   ++++T + G   L + 
Sbjct: 25073 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVK 25132

Query: 2975  DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRK 3034
             D+ + D G Y CK  N  GE  + + ++      + +   + + T  ++KI+   D++R 
Sbjct: 25133 DITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYD--YYCRRT--MKKIKRRTDTMRL 25188

Query: 3035  EPGQQPDDDTGRPPEFT-TVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA 3093
                        RPPEFT  ++     + E    +    +  T      + W+ +G+ I+ 
Sbjct: 25189 ---------LERPPEFTLPLYNKTAYVGE----NVRFGVTITVHPEPHVTWYKSGQKIKP 25235

Query: 3094  SHRIRTVYAF----GMVVLEILGTKTTDSGTYSCRATNKWGQ----AEISVKLECVDKSK 3145
                 +  Y F    G+  L I    T D   Y+  A NK+G+    A+++V L       
Sbjct: 25236 GDNDKK-YTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDS 25294

Query: 3146  GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD-F 3204
               +P F   + N E  ++GQS  FE  V  +  P +K  W  +GQP+     I+ + +  
Sbjct: 25295 TLRPMFKRLLANAE-CQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGL 25351

Query: 3205  GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
              +  L I  T   D+G Y   A N  G    +A
Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQA 25384



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 53/209 (25%), Positives = 97/209 (46%), Gaps = 21/209 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P  I+ + +  ++ G     S  ++G P P +QW+    L+ PS  ++     D+++L I
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-----------TQPDQADNLPAL------- 4724
                 EDEG+Y C+A N  G+   +A LK+           T+   A +L  L       
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576

Query: 4725 --TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIG 4781
                L+ I   +G PA F+  +  +  PT+ W +E   +  +  + +IH  N +   ++ 
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3636

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED+G + C+A    G+   +A+L+V
Sbjct: 3637 DPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 71/248 (28%), Positives = 105/248 (42%), Gaps = 22/248 (8%)

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIV----PPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            E    +++     V   K ++  GG +    P   T     V+   G +V L T +T  K
Sbjct: 4212 EKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAK 4270

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD-SGKYECVAINSAGEARCDAE 4600
              +V W    K V  D + K L++  TYTL+I +   +D  G+Y C A+N +G+    A+
Sbjct: 4271 --EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAK 4328

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V             +AA      IEPL+   VA G   +F+C+I   P    QW+K  
Sbjct: 4329 LTVV-----------KRAAPVIKRKIEPLE---VALGHLAKFTCEIQSAPNVRFQWFKAG 4374

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            + I  S    +  +    +L I      D G+Y C A N  G V+  A L VT P     
Sbjct: 4375 REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKK 4434

Query: 4721 LPALTPLR 4728
            +  L P R
Sbjct: 4435 VRKLLPER 4442



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 110/510 (21%), Positives = 197/510 (38%), Gaps = 51/510 (10%)

Query: 1374  SVYPE--DSGVYTCQATNQLGEAVTSCALRVIAK-----KDLILESQHPSGLE-KIQYLE 1425
             SV+PE   +  Y   +  +  E   S ++R +       ++ +   +H +  E K   LE
Sbjct: 25986 SVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALE 26045

Query: 1426  DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKN 1483
             + S  +K+       T+  R +T+P+S+  V EG+   F C    EPV      V W + 
Sbjct: 26046 EKSLEEKSTTRKIKTTLAARILTKPRSM-TVYEGESARFSCDTDGEPVPT----VTWLRK 26100

Query: 1484  GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS-------CRLTC 1536
             GQ ++   R +          +I  + A D G Y+    N  G  E          R+T 
Sbjct: 26101 GQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTE 26160

Query: 1537  RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTD----MVDEVTTQAPICTTSLKNV----- 1587
             ++ T   R    E  ++  + ++   +    +         T   P  T  ++++     
Sbjct: 26161 KAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAP 26220

Query: 1588  -EIKEGQRAHFERRLIP----VSDATLK---VEWYHNNKPLKSGSRFT-ETNNFGFVALD 1638
              +I +  +A   + +      V  + L+   V WY + K LK    F    +  G   L 
Sbjct: 26221 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 26280

Query: 1639  IMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQ--LEDTSK 1696
             I +    D G Y C      G + T+   +  + KSI+ +        + +Q   E T  
Sbjct: 26281 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 26340

Query: 1697  YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
              +      E I+  PV    ++D  V+ +  A F  +    G+P+    W ++G  I   
Sbjct: 26341 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKA--TGEPRPTAIWTKDGKAITQG 26398

Query: 1757  NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-------KASLQ 1809
              +     D G   L +   +  DSG YTC   N  G   +S  L +++       K S Q
Sbjct: 26399 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 26458

Query: 1810  LESQHESALQKIQQLEDSSRYQRREDVEVA 1839
               S+     + + Q E S +  R E+++++
Sbjct: 26459 KTSEITPQKKAVVQEEISQKALRSEEIKMS 26488



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 97/373 (26%), Positives = 160/373 (42%), Gaps = 46/373 (12%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            W ++   I+ SP  +         L I  V + D+  +  V          +A LVVEE 
Sbjct: 4654 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE- 4712

Query: 4504 RRQGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                    +P  F  T  + V V  GQ + L  ++   K  DV W K+GK V       +
Sbjct: 4713 --------LPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIV 4762

Query: 4563 LEEDGTY-TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
                G    L I +A   D+G Y  V + +A    C + CV  +   +D           
Sbjct: 4763 PGVIGLMRALTINDADDTDAGTY-TVTVENANNLEC-SSCVKVVEVIRD----------- 4809

Query: 4622 PPEIIEPLKDK-IVAEGQAIEFSCKIVGKPLPTVQWYKG-DKL-IKPSKYFQMSRTADEY 4678
               +++P++D+ +  +G AI F+C I  K  P ++W+KG D++  +P+   ++ R  +  
Sbjct: 4810 --WLVKPIRDQHVKPKGTAI-FACDI-AKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHL 4865

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
             L+I  A PED  +Y   A    G+    AKL + + +    +  L P+ D+ +YE + A
Sbjct: 4866 YLKIKNAMPEDIAEY---AVEIEGK-RYPAKLTLGERE----VELLKPIEDVTIYEKESA 4917

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
             F  +I+    P  QW  +G L+  +P  ++  EG    L +     +  G    +A  A
Sbjct: 4918 SFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLRKVKLDQAGEVLYQALNA 4976

Query: 4799 AGQVETSAKLVVK 4811
                 T+A L VK
Sbjct: 4977 I----TTAILTVK 4985



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 94/350 (26%), Positives = 148/350 (42%), Gaps = 53/350 (15%)

Query: 1191  EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
             EG ++   C++E   D + +V W+   R +    +++  Y+ G   L +   T  D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 1251  TVRAVNHLG--SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVM 1308
               + VN  G  S++    V+ +     V D    + +++I+      RRT  +R    + 
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVRE---VYDYYCRRTMKKIK------RRTDTMR---LLE 25190

Query: 1309  QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP-AYEFD- 1366
             + P+F+  L+N     G NV     +    +    V W+ +G+ IK G   +   +E D 
Sbjct: 25191 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDK 25248

Query: 1367  -YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
                 L + SV  +D   YT  A N+ GE   SC     AK  + L   HP          
Sbjct: 25249 GLYQLTINSVTTDDDAEYTVVARNKYGE--DSCK----AKLTVTL---HP---------- 25289

Query: 1426  DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485
                    TD      T++P F  R  +     EGQ V FE ++  +    LK  W K+GQ
Sbjct: 25290 -----PPTD-----STLRPMF-KRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQ 25336

Query: 1486  PVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
             P+++G     IH+   Y AL I D + ED+G Y   A N  G+      L
Sbjct: 25337 PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHL 25386



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 95/397 (23%), Positives = 159/397 (40%), Gaps = 50/397 (12%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F   ++   V E  QARFE     E   +  W +    IK+S  F I     K IL+I  
Sbjct: 4991 FAVPLKDVTVPERRQARFECVLTREANVI--WSKGPDIIKSSDKFDIIADGKKHILVIND 5048

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
               +D  V+ A  E +    K SA L V   R +         F    ++  V  G+   
Sbjct: 5049 SQFDDEGVYTAEVEGK----KTSARLFVTGIRLK---------FMSPLEDQTVKEGETAT 5095

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
               +++  K + V W KN  K+       I  E  T+ L + E           V ++  
Sbjct: 5096 FVCELSHEK-MHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKE-----------VTLDDI 5143

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
             + +     V  L +T      Q K   A P     L DK   E   I   C+ V K +P
Sbjct: 5144 SQIKAQ---VKELSSTA-----QLKVLEADPYFTVKLHDKTAVEKDEITLKCE-VSKDVP 5194

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             V+W+K  + I PS  + +        L+I +A  +D+G+Y C       +  V  + ++
Sbjct: 5195 -VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARL 5253

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI--QWLREGALIPETPDFQMI 4770
             + ++        PL  + V+ G+ A F+ +++   +P +  QW  +G  +  +PD ++I
Sbjct: 5254 IKVEK--------PLYGVEVFVGETAHFEIELS---EPDVHGQWKLKGQPLTASPDCEII 5302

Query: 4771 HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             +G   +L++ N     TG  + +A  A        K
Sbjct: 5303 EDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVK 5339



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 78/308 (25%), Positives = 130/308 (42%), Gaps = 41/308 (13%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
            GR  +         ++VNV  G    L+ KV+      V W  N ++++PD R + + + 
Sbjct: 2392 GRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2451

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
                L+I   +  D G Y+ +        R +  C +S+   K               II
Sbjct: 2452 TKQRLVINRTHASDEGPYKLIV------GRVETNCNLSVEKIK---------------II 2490

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              L+D    E Q + F  ++    +  V W   DK IKPS  +++      Y L +    
Sbjct: 2491 RGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMM 2549

Query: 4687 PEDEGDYKCVAYNS--AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
             +DEG Y   A  +  +G++TVA                  PL D  V E Q A F+ ++
Sbjct: 2550 KDDEGKYTFYAGENITSGKLTVAGGA------------ISKPLTDQTVAESQEAVFECEV 2597

Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
             +      +WLR+G  +P T + +   +G+   L+I  T  +D G +T +  T+    +T
Sbjct: 2598 ANPDSKG-EWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KT 2652

Query: 4805 SAKLVVKS 4812
            SAKL V++
Sbjct: 2653 SAKLKVEA 2660



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 98/399 (24%), Positives = 165/399 (41%), Gaps = 52/399 (13%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            KK +     E+    FEV    + +P +KW+ +N  IK S   ++ +      L+++ + 
Sbjct: 2753 KKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 2811

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
              D+  + AV     G  +C A L VE               T T +N+ V   +    +
Sbjct: 2812 PSDAGEYTAVV----GQLECKAKLFVETLH-----------ITKTMKNIEVPETKTASFE 2856

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +V+    +   WLKNG +++   + KI+ +   + L+I+    +DS +Y  V     G 
Sbjct: 2857 CEVSHFN-VPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGN 2911

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V+                 P  I   LKD    E   I F   +  + + + 
Sbjct: 2912 DQVSATLTVT-----------------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SY 2953

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W K    IK +   QM      ++L I      D  DY  V    AG+ T  A L V  
Sbjct: 2954 KWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFV----AGKATSTATLYV-- 3007

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
              +A ++     ++DI V E + A F+ ++ S+   T+QW+++   +  T   ++  E  
Sbjct: 3008 --EARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               LLI +T   D G +T     A G V T AKL V+ +
Sbjct: 3065 VHRLLIPSTRMSDAGKYT---VVAGGNVST-AKLFVEGR 3099



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 120/546 (21%), Positives = 212/546 (38%), Gaps = 85/546 (15%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            +Y   A R        V   + P+ L  L+    +  G+ A F A +  +      + WY
Sbjct: 3171 EYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVT-VQSGKPARFCAVISGRPQ--PKISWY 3227

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
               + +++  + +  HD     L +     ED+ VYT  A+N  G A  SAS++VE    
Sbjct: 3228 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV--- 3284

Query: 1141 IDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECR 1200
                                + V P    +E+    P  + PL +    SEG+    +CR
Sbjct: 3285 -------------------PEVVSP---DQEMPVYPPAIITPLQD-TVTSEGQPARFQCR 3321

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
               +    ++V W+   + +     F+         L+I  A   D G YT  A N +G 
Sbjct: 3322 ---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ 3378

Query: 1261 AHTSAIVRVIERSDIVTDTQNEQAIE-------------QIQLLEDAARRTKQVREDITV 1307
              ++A +  +E  + +   + EQ IE             + + L  A  +  ++ E + +
Sbjct: 3379 VSSTANLS-LEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLEL 3437

Query: 1308 M-QAPQFSRALHN---------IETVEGTNVHL----ECRLQPVGDQTMRVEWFCNGKPI 1353
            + ++P +S    +         I+ V   ++ +       +  +G    +++WF NG  +
Sbjct: 3438 LSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLL 3497

Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK----KDLI 1409
                 ++  ++ D  +L +L    ED G YTC A+N  G+ + S  L++ +K    KD  
Sbjct: 3498 TPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTE 3557

Query: 1410 LESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLE 1469
             ES     LEK+                      P F+   K I    +G    FE  + 
Sbjct: 3558 TESAVAKSLEKL-----------------GGPCPPHFLKELKPI-RCAQGLPAIFEYTV- 3598

Query: 1470 PVTDSNLKVEWFKNGQPVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             V +    V WFK  + +     +  IH+  G     + D   EDSG+Y C+A N++G  
Sbjct: 3599 -VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGES 3657

Query: 1529 EVSCRL 1534
              +  L
Sbjct: 3658 TCAAEL 3663



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 72/298 (24%), Positives = 117/298 (39%), Gaps = 16/298 (5%)

Query: 3513 QGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI---- 3568
            + +  + ++ ++   + GT  +    E   G    +T  A    P E   TP  L+    
Sbjct: 845  KSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLK 904

Query: 3569 ---LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
               + E  S   EC +      S  V W+     + +    +     G   L I   +  
Sbjct: 905  NVTVIEGESVTLECHISGY--PSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 962

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ-LPSHFKSGTESIQKLEETLHKREE 3684
            D+G +TC A N  G  + SC L V+  +    E   +   F +  +   +  + +     
Sbjct: 963  DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTS 1022

Query: 3685 ITIEDEKPNPPRFTVEIKDNI--DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742
            +T E   P  P     I   +   + EGG V F C+V   G+P   + W  +G P  TG 
Sbjct: 1023 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1080

Query: 3743 R--VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
            R  V      G   L I   +A DAGEYT    NK G  + +A +   A  +++++SQ
Sbjct: 1081 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1138



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/282 (24%), Positives = 121/282 (42%), Gaps = 20/282 (7%)

Query: 3667 SGTESIQKLEETLHKREEITIED-------EKPNPPRFTVEIKDNIDVPEGGPVHFDCRV 3719
            +GT   ++  E LH RE    E        E P  P   V    N+ V EG  V  +C +
Sbjct: 861  TGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHI 920

Query: 3720 EPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779
               G P+  + W+       +          G   L I   +A D+G +TC A N+ G+ 
Sbjct: 921  S--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 978

Query: 3780 TTTAKITCSAKRDIVLESQ-LPQGMSGEKIKELERGRI--SDAPKEE----PIVSTPPKF 3832
            +T+  +      +   E+  + +  + E+ + +E   +  +D    E    P     P F
Sbjct: 979  STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1038

Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM--GFVSLD 3890
            IT+     + E   V F C+V    +PK  + W ++G  L +G+RY+  Y+   G   L 
Sbjct: 1039 ITKPVVQKLVEGGSVVFGCQVGG--NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLV 1096

Query: 3891 ILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            I   +A+D+GEY     N  GE    A++  +   ++++++Q
Sbjct: 1097 ISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1138



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/271 (25%), Positives = 121/271 (44%), Gaps = 16/271 (5%)

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320
            RE +  + A+   P      PP  ++ +++VT ++EG+S   E  +     P   V W+ 
Sbjct: 876  REAKVTETARVPAPVEIPVTPPTLVSGLKNVT-VIEGESVTLECHISGYPSPT--VTWYR 932

Query: 3321 NGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
               ++     ++     GI  L I   + E+SG + C A N+ G  ST   L     E  
Sbjct: 933  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 992

Query: 3381 ILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKG-----KAPVF-TVPLSNIENLRE 3434
              ++      +   E+ + +E   V   DTS+ EE+       AP F T P+  ++ L E
Sbjct: 993  EKETTAVT-EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVE 1049

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSGE 3492
            G +  F  ++     P+  V W  +G  L  G R++   +   G   L IS T+ +D+GE
Sbjct: 1050 GGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1107

Query: 3493 YLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            Y     N +GE   +AS+  +    ++++SQ
Sbjct: 1108 YTIVVRNKHGETSASASLLEEADYELLMKSQ 1138



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 89/373 (23%), Positives = 153/373 (41%), Gaps = 52/373 (13%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E A F+ E   E +P ++WY +   ++ S      +      L +R V +ED+      A
Sbjct: 5714 ETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTA 5772

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
            ++     K  ANL V+E          P  FT   ++  V  G    L+ +V+  +   V
Sbjct: 5773 KD----FKTHANLFVKEP---------PVEFTKPLEDQTVEEGATAVLECEVS-RENAKV 5818

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W KNG ++    + +I+ +     L+I +  P+D   Y C A +   +  C+   V   
Sbjct: 5819 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSCNLNVV--- 5873

Query: 4606 PATKDKPKPQTKAANAPP--EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
                            PP  E + PL D  V E +   F C++  +    V+W+K    I
Sbjct: 5874 ----------------PPHVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEI 5916

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS--AGRVTVAAKLKVTQPDQADNL 4721
            K  K + +        L I++   +DE +Y C    +  +G +TV  +  V   +     
Sbjct: 5917 KKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKN----- 5971

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
                 L +I V E    +   ++ SK    + W +    I ET  ++++ EG   +L+I 
Sbjct: 5972 -----LANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 6025

Query: 4782 NTYEEDTGTFTCR 4794
            N + ED G + CR
Sbjct: 6026 NAHLEDAGNYNCR 6038



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 85/361 (23%), Positives = 147/361 (40%), Gaps = 22/361 (6%)

Query: 513   RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN----V 568
             +A G P P   W KDG  I    + ++  D G   L+I +   SD+  Y CT +N    V
Sbjct: 26377 KATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSV 26436

Query: 569   AGSTATRARLYXXXXXXXXXXQKRLHLPRPTK--VXXXXXXXXXXXXYLRHVE-RARPYI 625
             + S     +            QK   +    K  V             ++  E +++  +
Sbjct: 26437 SSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKL 26496

Query: 626   PPGEE-DRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
                EE  +V    +  V   + T++E   +H     E +   +   E ++    I+A S 
Sbjct: 26497 ALKEEASKVLISEE--VKKSAATSLEKSIVH-----EEITKTSQASEEVRTHAEIKAFST 26549

Query: 685   FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK-AVLHVTPRATIERTSQHPE- 742
               SI     + L        D  ++    V  T   E +  V       TI++ S   E 
Sbjct: 26550 QMSINEGQRLVLKANIAGATDV-KWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26608

Query: 743   TLQYIQQL-EDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPT 801
              L  I +  E   K Q+  ++ ++ S  P FI   +    + EG+N  F  +++   +P+
Sbjct: 26609 ILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQN-INEGQNVLFTCEIS--GEPS 26665

Query: 802   MRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIR 861
               +EW+K+  PI+ SS ++   +    SL I +    D+G YT++A N  G+  +TAS+ 
Sbjct: 26666 PEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLM 26725

Query: 862   V 862
             V
Sbjct: 26726 V 26726



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 16/234 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLS--GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            P   +K  + +L+    A F+ +L+  G+P   V W  +G+ L  +N+  +I    + +L
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1716

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG  T  A N  G   TS  L V+       + Q  +     Q+ E  ER+
Sbjct: 1717 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1776

Query: 384  EISEKALA-----------PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
               E AL            P  V   +   V EG+  RF CRVTG P P+V W++N + I
Sbjct: 1777 -AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLI 1835

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
            R   + +  V   G H L I +    D+G V   A N  G    + +L + ++E
Sbjct: 1836 RK--SKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1887



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 67/284 (23%), Positives = 117/284 (41%), Gaps = 17/284 (5%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P F    ++    +G N  F  ++ G P+P + W +   P+   +  S+  +      SL
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV--YSL 26694

Query: 132   LIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
              I+     D G+YT  A+N  G+  A  S+ + P                R   +T    
Sbjct: 26695 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLP-----LVEEPSREVVLRTSGDTSLQG 26749

Query: 190   AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREV--SFRESITKRYVGE 247
             ++ +Q      S+Q    +  + +  SS  + K  +   + +  +  SF E  +  ++G 
Sbjct: 26750 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26809

Query: 248   SDV-QISTEIDRSLGPVS---PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             S++ Q+ +   + L       PPKI   P +  + EG         +G P P VTW   G
Sbjct: 26810 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26869

Query: 304   QRLIN--SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +++ +    +  I  T + TTL + + QK D G YTL   N  G
Sbjct: 26870 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 74/279 (26%), Positives = 112/279 (40%), Gaps = 27/279 (9%)

Query: 3011 ERTQHPKGTEGLE--KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHY 3068
            E +    GTE +   KIQ  E    KE G          P   T   D V   EG I H 
Sbjct: 4214 EESSSESGTEEVATVKIQEAEGGFIKEDG----------PMIHTPLVDTVS-EEGDIVHL 4262

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD-SGTYSCRATN 3127
              S+    +    + W++  K + +  + + +       L I    T D  G Y C A N
Sbjct: 4263 TTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALN 4318

Query: 3128 KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187
              G+   S KL  V ++    P     I+ +E +  G  A F C +     P+++ +W+ 
Sbjct: 4319 DSGKTATSAKLTVVKRAA---PVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFK 4372

Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG- 3246
             G+ +  S +    S      L+I  TQ  D GEY C+A N+YG     AT+     GG 
Sbjct: 4373 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGE 4432

Query: 3247 VYLESLQPDSLAKIRELESLQGAQQQTP--STPSAEPPK 3283
              +  L P+   + +E   L+   ++ P    P  EP K
Sbjct: 4433 KKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKK 4471



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 56/189 (29%), Positives = 83/189 (43%), Gaps = 6/189 (3%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I  PL D +  EG  +  +  I       V WY  +KL+   + F+  +  + YTL I
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVI 4300

Query: 4683 SEAFPED-EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
             +   ED +G+Y C A N +G+   +AKL V +         + PL    V  G  A+F 
Sbjct: 4301 DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLE---VALGHLAKFT 4357

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +I S      QW + G  I E+    +      + L I  T   D G +TC+A+   G 
Sbjct: 4358 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 4417

Query: 4802 VETSAKLVV 4810
            V  +A L V
Sbjct: 4418 VSCTATLTV 4426



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 76/284 (26%), Positives = 117/284 (41%), Gaps = 24/284 (8%)

Query: 1553 EQIQVLEDR-SKYHRTDMVD---EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDAT 1608
            E+ +VL  R +K   T  V    E+    P   + LKNV + EG+    E  +      T
Sbjct: 868  ERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT 927

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
              V WY  +  ++S   F  T   G   L I     EDSG +TC A+N  G   TS    
Sbjct: 928  --VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLA 985

Query: 1669 VHSKKSIYLES----------QHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVF-TMPM 1717
            V   +    E+          +      R   + DTS  +  +   E    AP F T P+
Sbjct: 986  VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGE--PAAPYFITKPV 1043

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYVALNMKYV 1775
               ++ E  +  F  ++   G+PK  V W ++GVP+    R    ++   G   L +   
Sbjct: 1044 VQ-KLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMT 1100

Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
              +D+G YT    N+ GE   S++L  ++   L ++SQ E   Q
Sbjct: 1101 FADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQ 1144



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 52/182 (28%), Positives = 81/182 (44%), Gaps = 2/182 (1%)

Query: 391   APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHA 449
             AP F +  ++ +V         C+VTG P P V W+   ++I  D   ++I   + G H 
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489

Query: 450   LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
             L+I +VT  D+ V    A N+ G  +    L V    ++  PK +E    ++   GE V 
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVS 24549

Query: 510   LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR-AKASDAAWYQCTAQNV 568
             +     G P P ITWQK    I  N   ++      ++L  P   +  DA +Y   A+N 
Sbjct: 24550 IKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNR 24609

Query: 569   AG 570
              G
Sbjct: 24610 FG 24611



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 70/280 (25%), Positives = 120/280 (42%), Gaps = 20/280 (7%)

Query: 922   KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
             +EGG   +  ++E    ST +V W    R +E S +    +  G   L +K +T  D G 
Sbjct: 25083 EEGGHVKYVCKIENYDQST-QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 25141

Query: 982   YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
             Y C+  N  G+ ++ A L +   +++              Y     +  KR  + +++ +
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVREVYD-----------YYCRRTMKKIKRRTDTMRLLE 25190

Query: 1042  K-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY---HD 1097
             + P F  PL      V G++  F   +    +  +T  WY +G++I   +  + Y    D
Sbjct: 25191 RPPEFTLPLYNKTAYV-GENVRFGVTITVHPEPHVT--WYKSGQKIKPGDNDKKYTFESD 25247

Query: 1098  FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
              G   L I SV  +D   YTVVARN  GE    A +TV T     T S  R ++++    
Sbjct: 25248 KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-TLHPPPTDSTLRPMFKRLLAN 25306

Query: 1158  EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHL 1197
              E +  + +     +S   P  ++   +  P+S G NI +
Sbjct: 25307 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEI 25346



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 87/390 (22%), Positives = 146/390 (37%), Gaps = 19/390 (4%)

Query: 489   VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
             +A + + +  ++ V EGE    +    G P P +TW + G  +  +   ++ T    ST 
Sbjct: 26062 LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF 26121

Query: 549   DIPRAKASDAAWYQCTAQNVAGS-----TATRARLYXXXXXXXXXXQKRLHLPR---PTK 600
             +I   +ASD   Y    +N  G      T T  +            + +   PR   P  
Sbjct: 26122 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 26181

Query: 601   VXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYP---PPQFIVPLKSVTAMEGGKIHFE 657
             V            + + V        P E+ +  P   PP+    LK+  + E  K+   
Sbjct: 26182 VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKL--T 26239

Query: 658   TRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSA 716
               +E       ++ W K+G+ ++ +  F   +   G   L + +L   D GEY C     
Sbjct: 26240 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGE 26299

Query: 717   TGVAETKAVLHVTPRATI-ERTSQHPETLQYIQQLEDYSKYQHQE-SIEEQTSQRPQFIR 774
              G ++T          +I E+ S+  ET +  Q+  + +  +  E    E  S +P  + 
Sbjct: 26300 GGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVT 26359

Query: 775   PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMH 834
              LQD   +     A F  + T    PT    W KDG+ IT   +     + G   L I  
Sbjct: 26360 GLQDT-TVSSDSVAKFAVKATGEPRPT--AIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 26416

Query: 835   LRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
                 D+G YT    N  G   S+  + + A
Sbjct: 26417 TDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26446



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 3/183 (1%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            ++IE+S    AP+  +  Q + V +G    F  RV G+P PE  W+ N  +I        
Sbjct: 2021 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2080

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
               E     L+I +VT  DS  +   A N +GET+    L +++ +Q++   F +    +
Sbjct: 2081 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLIT--FTQELQDV 2137

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +E + +         P  ++ W KDG+ +    + R+H+D     L I     SDA  
Sbjct: 2138 VAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAED 2197

Query: 561  YQC 563
            Y C
Sbjct: 2198 YSC 2200



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 46/192 (23%), Positives = 84/192 (43%), Gaps = 3/192 (1%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P I + +KD     G+A + SC+IVG+PLP ++WY+  K +  S+ ++MS     +TL +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                  EDEG Y C+A N  G V  ++KL +    Q    P            G   +   
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFH--PGYPLKEKYYGAVGSTLRLHV 24153

Query: 4743  QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE-DTGTFTCRATTAAGQ 4801
                 +  P + W     L+  + +  + +  +   L++ N   +   G +  + +   G 
Sbjct: 24154 MYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 24213

Query: 4802  VETSAKLVVKSK 4813
             V+    + ++ K
Sbjct: 24214 VDAILDVEIQDK 24225



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 69/247 (27%), Positives = 97/247 (39%), Gaps = 11/247 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P     L N+  + EGE+   E  ++    P   V WY     +++   F+     G   
Sbjct: 897  PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIAR 953

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDK-IAAL 3538
            L I   + EDSG + C A N  G   T+  + VQ       E+        T +K     
Sbjct: 954  LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013

Query: 3539 EGYSGTVDTLTPE-AESGNP--PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
                 T  +LT E A  G P  P F T P    L E  S  F C++    +    V W  
Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKK 1071

Query: 3596 NGKPLLTGSRVKTI--NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G PL TG R K       G   L I   +  DAG YT    N+HGE + S  L  +   
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131

Query: 3654 GIILEPQ 3660
             ++++ Q
Sbjct: 1132 ELLMKSQ 1138



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 64/235 (27%), Positives = 103/235 (43%), Gaps = 28/235 (11%)

Query: 3839  HTVEESEG-VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
             H V E  G V++ C++E   D   ++ WY   + L +  +Y   Y+ G   L +  +   
Sbjct: 25079 HAVGEEGGHVKYVCKIE-NYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 25137

Query: 3898  DSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEV 3957
             D G Y C+ VND+GED + A +  K + + +      R MK+          IK+ T  +
Sbjct: 25138 DDGTYRCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKK----------IKRRTDTM 25186

Query: 3958  YLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG---K 4014
              L E         +PP F   + ++T+ V  E  +F   +    +P+  V W+ +G   K
Sbjct: 25187 RLLE---------RPPEFTLPLYNKTAYVG-ENVRFGVTITVHPEPH--VTWYKSGQKIK 25234

Query: 4015  PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
             P  +  ++T   D G   +    V  +D  EY   A N YG D  KA +  T  P
Sbjct: 25235 PGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP 25289



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 37/91 (40%), Positives = 51/91 (56%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP ++  LK+  V EG+++   C I G P PTV WY+ D  I+ S  FQ++  +    L 
Sbjct: 896  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            I EAF ED G + C A N AG V+ +  L V
Sbjct: 956  IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 83/384 (21%), Positives = 154/384 (40%), Gaps = 28/384 (7%)

Query: 2787  EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
             EG++  F C+ +    PT  + W    + L +  R++ T      + +I+     D G Y
Sbjct: 26077 EGESARFSCDTDGEPVPT--VTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 26134

Query: 2847  TCKATNSKGSATTSGSLRC----TGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPS 2902
             +    NS+G      +L        +K +    +    +  +++ E  +  +  K   PS
Sbjct: 26135 SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPS 26194

Query: 2903  VPDTEYP---KP---EWI--IPIAAEHQLVE-------GQVLHLEGQVEPKNDPDLKIEW 2947
              P    P   KP   E +  +P++A  ++ +        ++  L   VE       ++ W
Sbjct: 26195 HPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTW 26254

Query: 2948  YFNGKVLEQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
             Y +GK L++   F+   S  G   L + ++ E D G Y C+   + G + T+      + 
Sbjct: 26255 YKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAF 26314

Query: 3007  DNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIA 3066
              ++ E+      T+  ++        RK   + P+  + +P    T  +D   +S   +A
Sbjct: 26315 KSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV-IVTGLQDTT-VSSDSVA 26372

Query: 3067  HYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRAT 3126
              +      TG+      W  +GK I    + +     G   LEI  T T+DSG Y+C   
Sbjct: 26373 KFAVKA--TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK 26430

Query: 3127  NKWGQAEISVKL--ECVDKSKGQK 3148
             N  G    S KL  + +  ++ QK
Sbjct: 26431 NSAGSVSSSCKLTIKAIKDTEAQK 26454



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 65/233 (27%), Positives = 94/233 (40%), Gaps = 15/233 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
            EG+    E  +   G PS    WY    +++    F+ T   G   L I    A D+G +
Sbjct: 910  EGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967

Query: 2582 MCKAINRAGXXXXX------XXXXXXXXXXIIDQAMRPESWEQIQLKEAAM--NKVPEMF 2633
             C A+N AG                      + +    E    ++ ++  M    + E  
Sbjct: 968  TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1027

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
               G   AP F T      KLVEG  V    QV     P+  + W K+GV LTTG R K 
Sbjct: 1028 AGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKV 1084

Query: 2694 TFD--FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
            +++   G   L I+    DD+G YT    N  GE  ++AS+  E  + LL +S
Sbjct: 1085 SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1137



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 146/697 (20%), Positives = 268/697 (38%), Gaps = 67/697 (9%)

Query: 1691  LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
             LE+ S  ++ + +    T A       + + V E ++A F       G+P   V WLR G
Sbjct: 26044 LEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTD--GEPVPTVTWLRKG 26101

Query: 1751  VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ----SKA 1806
               +  S R             +  V   D G Y+    N  G+     TL +Q    ++ 
Sbjct: 26102 QVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEK 26161

Query: 1807  SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQA---------PRFITQ---LNGPT 1854
             ++    + +S   +++  E     +R +  E +  +A         P    Q   ++ P 
Sbjct: 26162 AVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPP 26221

Query: 1855  KLSE-------GQSAHYECRIEPYPDPNMRVEWYFNGKVL-QSGH-RYRTSNDFGFAALD 1905
             K+++        + A   C +E        V WY +GK L ++GH ++  S D G   L 
Sbjct: 26222 KITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD-GTYELK 26280

Query: 1906  ILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYK 1965
             I  +   D GEY C+     G + ++++   Q+ +SI       S  +K      +S   
Sbjct: 26281 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 26340

Query: 1966  RAVQDDSF--VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023
             R  +  +   +  KP     +++  V+           T   +P     W  +G+ + QG
Sbjct: 26341 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT--GEPRPTAIWTKDGKAITQG 26398

Query: 2024  HRFKTTYDFGYVALDILYAYAEDTGTYM-------------CKAT-NAVG--EAVTTSSV 2067
              ++K + D G   L+I      D+G Y              CK T  A+   EA   S+ 
Sbjct: 26399 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 26458

Query: 2068  KVDA----KSGLYLDTLDEQRLK----KIQELEKYERPKPIEEEQPG--QRPVFLTALTS 2117
             K       K  +  + + ++ L+    K+ E +  E+    EE         V  +A TS
Sbjct: 26459 KTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATS 26518

Query: 2118  LENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE 2177
             LE     +      +       H  I  F     I  G R     +    A D+ +    
Sbjct: 26519 LEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG-ATDVKWVLNG 26577

Query: 2178  DSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEP 2237
                T   +    +  +  T T+K A HR+  + T      E I + +       + + + 
Sbjct: 26578 VELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYD-----LTLSKE 26632

Query: 2238  KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297
                 P F+++ R + ++ EG+   F C++    +P+  IE++ N   +  ++   I+   
Sbjct: 26633 LSDAPAFISQPR-SQNINEGQNVLFTCEISG--EPSPEIEWFKNNLPISISSNVSISRSR 26689

Query: 2298  GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
                SL+I++    D+G+Y++KA N  G C++  S+ V
Sbjct: 26690 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 82/376 (21%), Positives = 142/376 (37%), Gaps = 33/376 (8%)

Query: 2388  IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
             + EG++A F C     G+P   V W R  +++  S+R   T      +  IS V+  DEG
Sbjct: 26075 VYEGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEG 26132

Query: 2448  VYMCRASNLLGEXXXXXXXXXXXXXXIQL-------------ETQHPEGMKKIQKLEQPH 2494
              Y     N  G+               +                + PE +K  ++++ P 
Sbjct: 26133 NYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPE 26192

Query: 2495  ERRSEEPDREFEKPIFTQVL-----TGPSELWEGQHAHYE---ARVVPVGDPSL----RF 2542
                 +       KP  T+ +     + P ++ +   A      A++  V + S+      
Sbjct: 26193 PSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEV 26252

Query: 2543  EWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXX 2601
              WY +G +LK    F+  +   G   L IN++  +D G Y+C+     G           
Sbjct: 26253 TWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQ 26312

Query: 2602  XXXXIIDQAMRPESWEQIQLK--EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQH 2659
                 I ++  +    ++   K  E+ + +  E      +   P+  T L+  D  V    
Sbjct: 26313 AFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQ--DTTVSSDS 26370

Query: 2660  VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKA 2719
             V   A V+   +P     W K+G  +T G + K + D G   L I+     DSG+YTC  
Sbjct: 26371 VAKFA-VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTV 26429

Query: 2720  TNLLGEAVSTASIKIE 2735
              N  G   S+  + I+
Sbjct: 26430 KNSAGSVSSSCKLTIK 26445



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 75/321 (23%), Positives = 126/321 (39%), Gaps = 27/321 (8%)

Query: 240  ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
            + +   G S + +   ++     V P    +K +N  ++EG+  + +V+ +GNP P + W
Sbjct: 1485 VAQNRAGRSSISVILTVEAVEHQVKP-MFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVW 1543

Query: 300  FKNGQRLINSN--KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE- 356
             KN   ++     K  I  T     L++ +T   DS  YT  A N  G   T   + VE 
Sbjct: 1544 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603

Query: 357  ------------SPTESY------VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
                         P  +Y        +    ++   Q++  E  +   EK   P F K  
Sbjct: 1604 EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKL 1663

Query: 399  QDRDVTEGKMTRFDCRVT--GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
                +       F+CR+T  G P   V W ++D +  +  N   ++NE G  +L      
Sbjct: 1664 TSLRLKRFGPAHFECRLTPIGDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLDYGVAY 1722

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE--RFSTLNVREGEPVVLNARA 514
              DSG++TC A NK G       L V +++ +V    +   R     + E E +      
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGAL 1782

Query: 515  VGTPTPRITWQKDGVPIIPNP 535
             G  T +   QK  + + P P
Sbjct: 1783 TGVTTDQKEKQKPDIVLYPEP 1803



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 65/248 (26%), Positives = 96/248 (38%), Gaps = 19/248 (7%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K    PIF K++    +   + A   V   G P P I+W+     +  S D++       
Sbjct: 3452 KEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDD 3511

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR---------------GG 4510
              LII    +ED   +  +A N  G   CSA L +  K    +               GG
Sbjct: 3512 HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 3571

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTY 4569
              PP F    + +    G     +  V G     V W K  K++   +   I+   +G+ 
Sbjct: 3572 PCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 3631

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT--KDKPKPQTKAANAPPEIIE 4627
            T ++ +   +DSG Y C A N  GE+ C AE +V L  T   D P        AP +  +
Sbjct: 3632 TFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQ 3691

Query: 4628 -PLKDKIV 4634
             PLK   V
Sbjct: 3692 TPLKGPAV 3699



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 96/405 (23%), Positives = 167/405 (41%), Gaps = 51/405 (12%)

Query: 4409 KPPI-FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP+ FTK ++   V E   A  E E   E    +KW++    I  S  ++I        
Sbjct: 5785 EPPVEFTKPLEDQTVEEGATAVLECEVSRENAK-VKWFKNGTEILKSKKYEIVADGRVRK 5843

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP--SFTLTAQNVNV 4525
            L+I     ED   +   A++     K S NL            +VPP   F     ++ V
Sbjct: 5844 LVIHDCTPEDIKTYTCDAKD----FKTSCNL-----------NVVPPHVEFLRPLTDLQV 5888

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
               ++ R + +++  +   V W K+G +++   +  I+ +     L+I +    D  +Y 
Sbjct: 5889 REKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYS 5947

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C       E R  A     L   +++       AN     IE      V+E   I+  C+
Sbjct: 5948 C-------EVR-TARTSGMLTVLEEEAVFTKNLAN-----IE------VSETDTIKLVCE 5988

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             V KP   V WYKGD+ I  +  +++     +  L I  A  ED G+Y C   +S     
Sbjct: 5989 -VSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSS----R 6043

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
               K+KV +         ++  +++ + EG+ A+F   I+ +  P +QW R+   +    
Sbjct: 6044 TDGKVKVHEL----AAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGD 6098

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCR--ATTAAGQVETSAKL 4808
             + +I +G   VL++ +   +D GT+     A  AA  +    KL
Sbjct: 6099 KYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKL 6143



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 61/306 (19%), Positives = 128/306 (41%), Gaps = 17/306 (5%)

Query: 4308  KVTSNTVAKSMAQRYEDNLDQTEEVTEQR---VQKKVTQKPRIPDPSESTVHGKEVHVAK 4364
             K+T   +  + AQ+   +  +T E+T Q+   VQ++++QK    +  + +    +  +A 
Sbjct: 26441 KLTIKAIKDTEAQKV--STQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLAL 26498

Query: 4365  QKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFE 4424
             +++  K ++ ++      TS E + +  +     +  E     ++   F+ +M    + E
Sbjct: 26499 KEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMS---INE 26555

Query: 4425  HEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484
              ++   +    G     +KW      + NS +++     +   L I+Q    D  +   +
Sbjct: 26556 GQRLVLKANIAGATD--VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCI 26613

Query: 4485  AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
             ++ + G  KC  +L + ++          P+F    ++ N+  GQ V    +++G    +
Sbjct: 26614 SKTKEGIVKCQYDLTLSKELSDA------PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26667

Query: 4545  VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
             + W KN   +       I      Y+L I  A   DSGKY   A N  G+    A  +V 
Sbjct: 26668 IEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV- 26726

Query: 4605  LPATKD 4610
             LP  ++
Sbjct: 26727 LPLVEE 26732



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 56/215 (26%), Positives = 95/215 (44%), Gaps = 17/215 (7%)

Query: 3709  EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
             EGG V + C++E   D + ++ W+   R      +     + G   L +  I   D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 3769  TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
              C+  N +G  ++ A++     R+ V +    + M  +KIK     R +D  +   ++  
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTM--KKIK-----RRTDTMR---LLER 25191

Query: 3829  PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG---HRYRTVYDMG 3885
             PP+F   + + T    E VRF   +    +P   + WY++G+ +  G    +Y    D G
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 25249

Query: 3886  FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
                L I  V  +D  EY   A N +GED  KA ++
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLT 25284



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 80/338 (23%), Positives = 140/338 (41%), Gaps = 52/338 (15%)

Query: 1739  DPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
             D   +V W      +E S +    ++ G   L +K +   D GTY C+ +N+ GE  + +
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 1799  TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE 1858
              LFV+    +  +      ++KI++  D+ R   R          P F   L   T    
Sbjct: 25158 ELFVKGVREVY-DYYCRRTMKKIKRRTDTMRLLERP---------PEFTLPLYNKTAYV- 25206

Query: 1859  GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
             G++  +   I  +P+P+  V WY +G+ ++ G      ND  +        +  D G Y 
Sbjct: 25207 GENVRFGVTITVHPEPH--VTWYKSGQKIKPG-----DNDKKYT-------FESDKGLYQ 25252

Query: 1919  CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQ-----DDSF 1973
                       ++S+  +         D    + + + +Y ED  + K  V       DS 
Sbjct: 25253 L--------TINSVTTD---------DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDST 25295

Query: 1974  VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD-F 2032
             +  +P F + + NAE  EG  V  E  ++ +  PT++  W  +G+P+  G   +  ++  
Sbjct: 25296 L--RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGL 25351

Query: 2033  GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
              Y AL I     EDTG Y   ATN  G     + ++V+
Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 88/324 (27%), Positives = 125/324 (38%), Gaps = 61/324 (18%)

Query: 3077  DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ----A 3132
             DQS  + W++  + +E S +    Y  G+ +L +      D GTY C+  N +G+    A
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 3133  EISVK-------LECVDKSKGQK------------PRFTTHIQNIEGLKDGQSAHFECTV 3173
             E+ VK         C    K  K            P FT  + N      G++  F  T+
Sbjct: 25158 ELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYV-GENVRFGVTI 25216

Query: 3174  VPVDDPDMKIEWYHNGQPMRHSTRIKTV---SDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
                  P+  + WY +GQ ++     K     SD G   L I      D  EY   A NKY
Sbjct: 25217 TV--HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKY 25274

Query: 3231  GEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQD 3290
             GED      +C  K  V   +L P                   P T S   P F   + +
Sbjct: 25275 GED------SCKAKLTV---TLHP-------------------PPTDSTLRPMFKRLLAN 25306

Query: 3291  VTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD-FGIVILDILYCYE 3349
               +  EGQS  FE R+  +  P LK  W  +G+ L  G      H+      L I     
Sbjct: 25307 A-ECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLP 25363

Query: 3350  ENSGEYECVATNKLGRDSTKANLK 3373
             E++G Y   ATN  G  S +A+L+
Sbjct: 25364 EDTGYYRVTATNTAGSTSCQAHLQ 25387



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 68/248 (27%), Positives = 105/248 (42%), Gaps = 17/248 (6%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ +T  P  +  LK    ++EG+S   E  +      T+T  WY    QI S+   Q  
Sbjct: 891  EIPVTP-PTLVSGLKNVT-VIEGESVTLECHISGYPSPTVT--WYREDYQIESSIDFQIT 946

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID---TSSIHRGLYE 1152
               G   L I    AEDSG +T  A N AG    S  + V+     +   T+   +   E
Sbjct: 947  FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTE 1006

Query: 1153 KTRHIEESKFV--EPMYQIEEISKSKPVFVQPLSNP--PPVSEGKNIHLECRLEPMGDPT 1208
            + R +E    V  +     E+    +P     ++ P    + EG ++   C++   G+P 
Sbjct: 1007 EKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPK 1064

Query: 1209 MRVEWFHNGRSVTVGSRFKTYYD--FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
              V W  +G  +T G R+K  Y+   G   L I    + D GEYT+   N  G   TSA 
Sbjct: 1065 PHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG--ETSAS 1122

Query: 1267 VRVIERSD 1274
              ++E +D
Sbjct: 1123 ASLLEEAD 1130



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 92/390 (23%), Positives = 148/390 (37%), Gaps = 31/390 (7%)

Query: 3283  KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
             + +T+ + +T + EG+SA F        +P   V W   G+ L    R++          
Sbjct: 26065 RILTKPRSMT-VYEGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF 26121

Query: 3343  DILYCYEENSGEYECVATNKLGRDSTKANL---KCTSKENLILDSQLPRGMEGGLEKLQT 3399
             +I      + G Y  V  N  G+   +  L   K    E  +      +  E  ++  + 
Sbjct: 26122 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 26181

Query: 3400  LEDSMVRRKDTSVEEEKGKAPVFT----------VPLS---NIENLREGENAHFEARLTP 3446
             ++ S  R K       K  +P  T          +P+S    I    + E +   A+LT 
Sbjct: 26182 VK-SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTC 26240

Query: 3447  TDDPNL----KVEWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNY 3501
               + ++    +V WY +GK LK    F+  +   G   L+I+     D GEY+C      
Sbjct: 26241 VVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEG 26300

Query: 3502  GEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIAALEGYSGTVDTLTPEAESGNPPEF 3560
             G + T      Q  ++I    ++ K  E    D+       +   +   PE  S  P   
Sbjct: 26301 GTSKTNLQFMGQAFKSI--HEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV-I 26357

Query: 3561  TTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIG 3620
              T   D  +S +S A F  +     +      W  +GK +  G + K   D G   LEI 
Sbjct: 26358 VTGLQDTTVSSDSVAKFAVKA--TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIH 26415

Query: 3621  GVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
                  D+GLYTC   N  G  + SCKL +K
Sbjct: 26416 KTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26445



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 46/174 (26%), Positives = 87/174 (50%), Gaps = 9/174 (5%)

Query: 235   SFRESITKRYVGESDVQISTE--IDRSLGPVSPPKIAQKP------RNSKLQEGADAQFQ 286
             S  E ++K    +   Q +TE  + R   P +P  I+ KP      +++ +   + A+F 
Sbjct: 26316 SIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFA 26375

Query: 287   VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC 346
             V+ +G PRP   W K+G+ +    K+++        L +  T  SDSG YT   +N  G 
Sbjct: 26376 VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGS 26435

Query: 347   IVTSGYLAVESPTESYVQDQRSQYITD-TQQRETEERIEISEKALAPQFVKVCQ 399
             + +S  L +++  ++  Q   +Q  ++ T Q++   + EIS+KAL  + +K+ +
Sbjct: 26436 VSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSE 26489



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 75/317 (23%), Positives = 135/317 (42%), Gaps = 23/317 (7%)

Query: 2041 YAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPI 2100
            + +A+   TY  +A   V + V  S      +   + + L   R  K+ E  +   P P+
Sbjct: 835  FPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERF-EVL-HGREAKVTETARV--PAPV 890

Query: 2101 EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT 2160
            E   P   P  ++ L ++  + EG+    EC +     P  T+ W+    +I +   ++ 
Sbjct: 891  EI--PVTPPTLVSGLKNVTVI-EGESVTLECHISGYPSP--TVTWYREDYQIESSIDFQI 945

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT---QHPNGL 2217
            T   G   L I   +AEDSG + C A N+ G    +C L V        +T         
Sbjct: 946  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTT 1005

Query: 2218 EKIRQLEAQG-HSTRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQVEPVHD 2271
            E+ R +E++    T   + E +  P     P F+T+      + EG +  F CQV    +
Sbjct: 1006 EEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GN 1062

Query: 2272 PNLRIEFYHNGKALQSAARFHITFD--FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSA 2329
            P   + +  +G  L +  R+ ++++   G   L I     +DAGEY++   N  G  +++
Sbjct: 1063 PKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1122

Query: 2330 ISMTVTAKGSIISESQR 2346
             S+   A   ++ +SQ+
Sbjct: 1123 ASLLEEADYELLMKSQQ 1139



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 7/195 (3%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  V+ +++ T ++E E+   EC ++  G P+  V W+     +     F   +  G  
Sbjct: 896  PPTLVSGLKNVT-VIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIA 952

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
             +     + EDSG + C A N  G   T   +          ++       + E+ R +E
Sbjct: 953  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1012

Query: 4092 ASWQVTPEQVVEESKAR----CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
            +   V  +  + E +A       P F++ P    + EG    F C+V G+PKP V W  +
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072

Query: 4148 GNTIVNGSRYKLTYD 4162
            G  +  G RYK++Y+
Sbjct: 1073 GVPLTTGYRYKVSYN 1087



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 57/205 (27%), Positives = 88/205 (42%), Gaps = 20/205 (9%)

Query: 3311  DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
             D   +V W++  ++L +  +Y   ++ G+ IL +    + + G Y C   N  G DS+ A
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 3371  NLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIE 3430
              L        + D    R M+            + RR DT    E+   P FT+PL N +
Sbjct: 25158 ELFVKGVRE-VYDYYCRRTMK-----------KIKRRTDTMRLLER--PPEFTLPLYN-K 25202

Query: 3431  NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC---DFGFVILEISPTYP 3487
                 GEN  F   +T   +P+  V WY +G+ +K G   + +    D G   L I+    
Sbjct: 25203 TAYVGENVRFGVTITVHPEPH--VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTT 25260

Query: 3488  EDSGEYLCRAYNNYGEAVTTASMKV 3512
             +D  EY   A N YGE    A + V
Sbjct: 25261 DDDAEYTVVARNKYGEDSCKAKLTV 25285



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 77/331 (23%), Positives = 137/331 (41%), Gaps = 23/331 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I   P   ++ EG  A+F+ +++G P+P+V W+ NGQ +  S +  +     H  L +
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHY-LDI 1853

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-----SYVQDQRSQYITDTQ---QR 377
             + +  D+G   + AENP G I     L ++   +         + R ++        Q 
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQF 1913

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKM--------TRFDCRVTGRPYPEVTWFIND 429
            E ++     +     + VK+ +   +T  K+        ++F  R T   Y E    +  
Sbjct: 1914 EVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR-TEEGYYEAITAVEL 1972

Query: 430  RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQV 488
            +  + D +++ L+ ++ +  L  T   L++          K     F  + + IE    +
Sbjct: 1973 KSRKKDESYEELLRKTKDELLHWTK-ELTEEEKKALAEEGKITIPTF--KPDKIELSPSM 2029

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH-TDGGAST 547
             APK  ER  +  V +G       R VG P P   W K+GV I  +  +  +  +     
Sbjct: 2030 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2089

Query: 548  LDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            L I    A D+A     A N+AG T++ A L
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFL 2120



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 62/243 (25%), Positives = 103/243 (42%), Gaps = 25/243 (10%)

Query: 4481  FAAVAENRGGTAKCSANLV-VEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG 4539
             F   AEN  G ++     + ++ K   G      P      ++V    G+  +L  ++ G
Sbjct: 24006 FRVFAENETGLSRPRRTAMSIKTKLTSGEA----PGIRKEMKDVTTKLGEAAQLSCQIVG 24061

Query: 4540  TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                 D+ W + GK++    + K+  +  T+TL ++    +D G Y C+A N  GE    +
Sbjct: 24062 RPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSS 24121

Query: 4600  ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV-AEGQAIEFSCKIVGKPLPTVQWYK 4658
             + +  L AT     PQ            PLK+K   A G  +      +G+P+P + W+ 
Sbjct: 24122 KLL--LQAT-----PQFHPG-------YPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFH 24167

Query: 4659  GDKLIKPSKYFQMSRTADEYTLRISEAFPE--DEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             G KL++ S+   +  T + YT  + +        G YK    N  G  TV A L V   D
Sbjct: 24168 GQKLLQNSENITIENT-EHYTHLVMKNVQRKTHAGKYKVQLSNVFG--TVDAILDVEIQD 24224

Query: 4717  QAD 4719
             + D
Sbjct: 24225 KPD 24227



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/313 (24%), Positives = 127/313 (40%), Gaps = 39/313 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P  F + ++   V E + A F  +   E    +KWYR    IK    ++     +   LI
Sbjct: 6325 PTEFVEHLEDQTVTEFDDAVFSCQLSREKAN-VKWYRNGREIKEGKKYKFEKDGSIHRLI 6383

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   ++D   +A   E+R    K  A L VEE         +P       Q++    G 
Sbjct: 6384 IKDCRLDDECEYACGVEDR----KSRARLFVEE---------IPVEIIRPPQDILEAPGA 6430

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V    ++   K ++V WL+N   V    +++++ E   + L I +  P+D G+Y  +A 
Sbjct: 6431 DVVFLAELNKDK-VEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAK 6489

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            +   EAR   E   +         P+ K A+         +D +V  G+ +         
Sbjct: 6490 DK--EARAKLELAAA---------PKIKTAD---------QDLVVDVGKPLTMVVPYDAY 6529

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P    +W+K +   +P     +  TA++ + RI EA   D+G YK V  N  G+      
Sbjct: 6530 PKAEAEWFKEN---EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFIN 6586

Query: 4710 LKVTQ-PDQADNL 4721
            LKV   P    NL
Sbjct: 6587 LKVIDVPGPVRNL 6599



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 117/538 (21%), Positives = 220/538 (40%), Gaps = 83/538 (15%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            PQ ++ LQ +  +Q G+ A F A ++    P  ++ WYK+ + ++   +   + +    +
Sbjct: 3193 PQVLQELQPV-TVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3249

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L ++    EDA  YT  A N  G  ++T S   A+ S    ++  P+Q   +        
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYG--VATTS---ASLSVEVPEVVSPDQEMPV-------- 3296

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                               P   TP++D ++  EG  A F+ R   +  + L+V W    
Sbjct: 3297 -----------------YPPAIITPLQDTVT-SEGQPARFQCR---VSGTDLKVSWYSKD 3335

Query: 950  RPVEASS--RITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
            + ++ S   R+T F +     L I      D G YT  A NA+GQ +++ANL++   + I
Sbjct: 3336 KKIKPSRFFRMTQFEDT--YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESI 3393

Query: 1008 IAES-QHPGGLEKIQY-----------LEDAS-RYSKRTEEEVKITQKP----RFLGPLK 1050
            + E  +    +E  ++           L  A  + SK  E    +++ P    +F    +
Sbjct: 3394 LHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKE 3453

Query: 1051 GTNKIVEGQSAHFEARVEPQSDLTMTV--------EWYFNGKQITSANRIQTYHDFGYVA 1102
            GT  I   + ++ +  +   + L++TV        +W+FNG  +T +   +   D    +
Sbjct: 3454 GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHS 3513

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I   + ED G YT +A N  G+   SA + + ++          G  +       +K 
Sbjct: 3514 LIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG--------EGHKDTETESAVAKS 3565

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +E +          P F++ L    P+   + +        +G+P   V WF   + +  
Sbjct: 3566 LEKLG-----GPCPPHFLKELK---PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCT 3617

Query: 1223 GSRFKTYYDFGFVALDIIH-ATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDT 1279
               +   ++       I++     D+G Y  +A N LG +  +A + V+     +TDT
Sbjct: 3618 SVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 3675



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 59/243 (24%), Positives = 98/243 (40%), Gaps = 9/243 (3%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +S L N+   EG+++  EC++     PT  + W+  +  + S   ++ T       L I 
Sbjct: 900  VSGLKNVTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIR 957

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEA---VEQAEEA 2893
              + EDSG +TC A N  G+ +TS  L     +    +T     K   E    VE  +  
Sbjct: 958  EAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVV 1017

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
                           P   + I      +LVEG  +    QV    +P   + W  +G  
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVP 1075

Query: 2954 LEQGSRFKLT--SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011
            L  G R+K++     G   L +   +  D+G YT    NK GE   S+++   +   L+ 
Sbjct: 1076 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1135

Query: 3012 RTQ 3014
            ++Q
Sbjct: 1136 KSQ 1138



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 48/175 (27%), Positives = 72/175 (41%), Gaps = 7/175 (4%)

Query: 405  EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVV 463
            EG +      +T     EV W+  ++ +  D   K L +++  + L+I  V   D  G  
Sbjct: 4256 EGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEY 4312

Query: 464  TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
             C A N SG+TA   +L V+++    AP    +   L V  G            P  R  
Sbjct: 4313 VCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQ 4369

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            W K G  I  + +  I +    S+L+I R +  D   Y C A N  GS +  A L
Sbjct: 4370 WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 4424



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 6/136 (4%)

Query: 232   REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
             R+      I+K   G    Q    + + L     P    +PR+  + EG +  F  ++SG
Sbjct: 26605 RDEGILTCISKTKEGIVKCQYDLTLSKELSDA--PAFISQPRSQNINEGQNVLFTCEISG 26662

Query: 292   NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG-CIVTS 350
              P P + WFKN   +  S+   I  + N  +L +RN   SDSG YT+ A+N  G C  T+
Sbjct: 26663 EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 26722

Query: 351   GYLA---VESPTESYV 363
               +    VE P+   V
Sbjct: 26723 SLMVLPLVEEPSREVV 26738



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 55/218 (25%), Positives = 95/218 (43%), Gaps = 18/218 (8%)

Query: 3162  KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
             ++G    + C +   D    ++ WY   + + +S + +   + G  +L +      D G 
Sbjct: 25083 EEGGHVKYVCKIENYDQ-STQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 25141

Query: 3222  YVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE- 3280
             Y C+  N YGED + A +   G   VY      D   +     +++  +++T +    E 
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVREVY------DYYCR----RTMKKIKRRTDTMRLLER 25191

Query: 3281  PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG---HRYRTFHDF 3337
             PP+F   + + T  V G++  F   +     P+  V W+ +G+K+  G    +Y    D 
Sbjct: 25192 PPEFTLPLYNKTAYV-GENVRFGVTITV--HPEPHVTWYKSGQKIKPGDNDKKYTFESDK 25248

Query: 3338  GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
             G+  L I     ++  EY  VA NK G DS KA L  T
Sbjct: 25249 GLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 25286



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 94/396 (23%), Positives = 156/396 (39%), Gaps = 52/396 (13%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            ++   V E  +A  E +     +  +KWY  +  IK     Q     TK  L+I +    
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D   +  +     G  + + NL VE K +  RG           +++  T  Q V  + +
Sbjct: 2465 DEGPYKLIV----GRVETNCNLSVE-KIKIIRG----------LRDLTCTETQNVVFEVE 2509

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            ++ +  IDV W    K+++P  + KI      Y L +L     D GKY       AGE  
Sbjct: 2510 LSHSG-IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFY----AGENI 2564

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               +  V                 A   I +PL D+ VAE Q   F C+ V  P    +W
Sbjct: 2565 TSGKLTV-----------------AGGAISKPLTDQTVAESQEAVFECE-VANPDSKGEW 2606

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  K +  +   +      +  L I+    +D G+Y    Y  A   T +AKLKV    
Sbjct: 2607 LRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY---TYKVATSKT-SAKLKV---- 2658

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
              + +     L+++ V E Q A F  ++T      +QW++ G ++     + +  +G   
Sbjct: 2659 --EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIY 2716

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             L I N    D   +  R     G++  SA+L V++
Sbjct: 2717 SLRIKNCAIVDESVYGFR----LGRLGASARLHVET 2748



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 87/400 (21%), Positives = 165/400 (41%), Gaps = 50/400 (12%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            K +    VF  E A FE+E   EP    +W  +  P+  SPD +I     K ILI+    
Sbjct: 5258 KPLYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQ 5316

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            +  +   +  A N    AK +ANL V+E         +P  F     +V V      + +
Sbjct: 5317 LGMTGEVSFQAAN----AKSAANLKVKE---------LPLIFITPLSDVKVFEKDEAKFE 5363

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +V+  +P    WLK  +++  D R +++++   ++++I  A  +D  KY    +  A +
Sbjct: 5364 CEVS-REPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKY----MFEAED 5418

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
                 + ++     K                + PLKD    E ++  F+ ++    +  V
Sbjct: 5419 KHTSGKLIIEGIRLK---------------FLTPLKDVTAKEKESAVFTVELSHDNI-RV 5462

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W+K D+ +  ++   M      +++   +   +D    +  A   +      AKL V +
Sbjct: 5463 KWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSE----AKLTVLE 5518

Query: 4715 PDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
             D     P  T  L+D    E      + +I SK    ++W ++G  I  + +  +  +G
Sbjct: 5519 GD-----PYFTGKLQDYTGVEKDEVILQCEI-SKADAPVKWFKDGKEIKPSKNAVIKADG 5572

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               +L++    + D G +TC      G  +TS KL ++ +
Sbjct: 5573 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 5608



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 66/258 (25%), Positives = 108/258 (41%), Gaps = 17/258 (6%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            +++ EG     E  +      T  V W ++   +E+S      F  G   L I+     D
Sbjct: 906  VTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAED 963

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ---HPGGLEKIQYLEDASRY---SKR 1032
            +G +TC A N  G  +TS  L +   ++   E+         E+ +++E        +  
Sbjct: 964  SGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSL 1023

Query: 1033 TEEEVKITQK--PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN 1090
            TEE+    +   P F+       K+VEG S  F  +V    +    V W  +G  +T+  
Sbjct: 1024 TEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1080

Query: 1091 RIQTYHD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
            R +  ++   G   L I+   A+D+G YT+V RN  GE   SAS+  E    +   S   
Sbjct: 1081 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQE 1140

Query: 1149 GLYEK--TRHIEESKFVE 1164
             LY+   T  ++E K  E
Sbjct: 1141 MLYQTQVTAFVQEPKVGE 1158



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 166/768 (21%), Positives = 293/768 (38%), Gaps = 65/768 (8%)

Query: 3675 LEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
            LEE   ++  + I + +     F + IK N  + EG  V F C++   G P  +I W+ +
Sbjct: 1225 LEEDGEEKMAVDISESEAVESGFDLRIK-NYRILEGMGVTFHCKMS--GYPLPKIAWYKD 1281

Query: 3735 GRPFATGSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
            G+    G R     L D G  +L I  +   D G YT  A+N  G+A  + K+       
Sbjct: 1282 GKRIKHGERYQMDFLQD-GRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAP 1340

Query: 3793 IVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECR 3852
            +   + +P      +I+ L    +S +P         P  ++  +      S G R E  
Sbjct: 1341 LGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEET 1400

Query: 3853 VEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
             E + +   +  +                +D+  V   +   +    G+ I   VND+  
Sbjct: 1401 DESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQI---VNDYTH 1457

Query: 3913 DFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQP 3972
               K  I       +I+    P        + Q  A   + +  V LT +    V+ +  
Sbjct: 1458 ---KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRA--GRSSISVILTVE---AVEHQVK 1509

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLL-HKNRFTPIYDF-GY 4030
            P FV ++++       E ++ E ++   G+PN  + W  N   ++ HK     I    G 
Sbjct: 1510 PMFVEKLKNVNI---KEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE 1566

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT---GKPGIVYDSQLPKHMKSIEKI 4087
             A+       +DS  Y   A N  G D T+  +       +P       +P+     ++I
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 4088 R--EME-ASWQVTPEQVVE----ESKARCPPVFVSLPDAVTVEEGEWARFCCRVT--GHP 4138
               E+E    +   EQ  E    + + +  P F     ++ ++    A F CR+T  G P
Sbjct: 1627 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDP 1686

Query: 4139 KPRVMWLLNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXL 4197
               V WL +G  +   +R ++  + G    D       D+G I                L
Sbjct: 1687 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1746

Query: 4198 KVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGV-IDHRPELKPK 4256
             V     D + +++ +  P  +     QR E ELE+   E  +    GV  D + + KP 
Sbjct: 1747 IV----KDEKSLVEESQLP--EGRKGLQRIE-ELERMAHEGAL---TGVTTDQKEKQKPD 1796

Query: 4257 VIKEPE----TEWQQSVKRKKNEEY-YNKLQELENEQVIKES---RLR-ESTHQYAIPGD 4307
            ++  PE     E + +  R +   Y   K+    N Q+I++S   R+R +  H   I   
Sbjct: 1797 IVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDC 1856

Query: 4308 KVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQ 4367
            K       K  A+  E  ++   ++  Q+ +   +   R P+P        E HV +  +
Sbjct: 1857 KSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPR------PEFHVHEPGK 1910

Query: 4368 TQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK 4415
             Q EV   +++ R + +TET E+  K +  ER+    V      + +K
Sbjct: 1911 LQFEV---QKVDRPVDTTETKEVV-KLKRAERITHEKVPEESEELRSK 1954



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 81/337 (24%), Positives = 134/337 (39%), Gaps = 43/337 (12%)

Query: 1324  EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
             EG +V   C+++   DQ+ +V W+   + ++   ++   YE     L +  +   D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 1384  TCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIK 1443
              C+  N  GE  +   L V   ++ + +      ++KI+   DT R  +          +
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKRRTDTMRLLE----------R 25191

Query: 1444  PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
             P   T P   +    G++V F   +    + +  V W+K+GQ +  G      +D  Y  
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPH--VTWYKSGQKIKPGD-----NDKKYT- 25243

Query: 1504  LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
                      D G+Y    +N V TD+ +        T + R+   E   +    +     
Sbjct: 25244 ------FESDKGLYQL-TINSVTTDDDA------EYTVVARNKYGEDSCKAKLTVTLHPP 25290

Query: 1564  YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
                TD     +T  P+    L N E +EGQ   FE R+  +   TLK  W  + +PL  G
Sbjct: 25291 --PTD-----STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLG 25341

Query: 1624  SRFTETN-NFGFVALDIMSCLPEDSGTYTCRAINALG 1659
                   +    + AL I   LPED+G Y   A N  G
Sbjct: 25342 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 25378



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 53/200 (26%), Positives = 87/200 (43%), Gaps = 16/200 (8%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            D    Y  + + ++T  R+ ++   L  +F+   +D+ V EG+   F C ++      V 
Sbjct: 5052 DDEGVYTAEVEGKKTSARLFVTGIRL--KFMSPLEDQTVKEGETATFVCELSHEKM-HVV 5108

Query: 425  WFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            WF ND ++    +  +L++  G  H L +  VTL D   +    +  S  TA   +L V+
Sbjct: 5109 WFKNDAKLHT--SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSS-TA---QLKVL 5162

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            E +    P F  +       E + + L    V    P + W KDG  I+P+P+  I  DG
Sbjct: 5163 EAD----PYFTVKLHDKTAVEKDEITLKCE-VSKDVP-VKWFKDGEEIVPSPKYSIKADG 5216

Query: 544  GASTLDIPRAKASDAAWYQC 563
                L I +A   D   Y C
Sbjct: 5217 LRRILKIKKADLKDKGEYVC 5236



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 60/237 (25%), Positives = 91/237 (38%), Gaps = 16/237 (6%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
            EG +   E  ++    PT  V WY++   I +S      F  G   L I    AED+G +
Sbjct: 910  EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967

Query: 844  TVRAVNKLGEAISTASIRVAA------RSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXX 897
            T  AVN+ G   ++  + V         +T   +    E++R++E               
Sbjct: 968  TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1027

Query: 898  XXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR 957
                 P     P F T    Q  + EGG   F  ++   G+    V W K G P+    R
Sbjct: 1028 AG---PGEPAAPYFITKPVVQ-KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYR 1081

Query: 958  ITTFFN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
                +N   G   L I      DAG YT    N  G+ + SA+L      +++ +SQ
Sbjct: 1082 YKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1138



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 111/491 (22%), Positives = 179/491 (36%), Gaps = 38/491 (7%)

Query: 3182  KIEWYHNGQPMRHSTRIKT-VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             ++ WY +G+ ++ +   +   S  G   L I      D GEYVC    + G   T     
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26310

Query: 3241  CYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP----PKFITQIQDVTKLVE 3296
                   ++ E +   S  K  + ++ +    +     + EP    P  +T +QD T +  
Sbjct: 26311 GQAFKSIH-EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSS 26368

Query: 3297  GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDI---------LY- 3346
                A F  +     +P     W  +GK +  G +Y+   D G   L+I         LY 
Sbjct: 26369 DSVAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYT 26426

Query: 3347  CYEENSG---EYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK-LQTLED 3402
             C  +NS       C  T K  +D T+A    T K + I   +     E   +K L++ E 
Sbjct: 26427 CTVKNSAGSVSSSCKLTIKAIKD-TEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26485

Query: 3403  SMVRRKDT---SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWN 3459
              M   K     +++EE  K  +      +     E    H E  +T T   + +V  +  
Sbjct: 26486 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEE--ITKTSQASEEVRTH-- 26541

Query: 3460  GKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNII 3519
                +KA S   +  +   ++L+ +     D    L        E        V G    +
Sbjct: 26542 -AEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYG---VSGSDQTL 26597

Query: 3520  LESQLPKGMEGTIDKIAAL-EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFE 3578
                Q     EG +  I+   EG       LT   E  + P F + P    ++E  +  F 
Sbjct: 26598 TIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFT 26657

Query: 3579  CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
             C +    + S  +EWF N  P+   S V          LEI      D+G YT KA N  
Sbjct: 26658 CEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFR 26715

Query: 3639  GEATVSCKLQV 3649
             G+ + +  L V
Sbjct: 26716 GQCSATASLMV 26726



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 10/203 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVY 3101
            T + P FT   + +V + EG  A +EA +  +G     + WF +G+ I  S    ++  +
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
            + G   L I      +SG YS +ATN  GQA  + +L  + K++   P F   +Q++  +
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMT-V 115

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            + G     +  V  +  P +K  +Y +G  ++ S   +   +     L IA     DSG 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGT 173

Query: 3222 YVCRAYNKYGEDFTRATINCYGK 3244
            Y   A N  G   + A +   G+
Sbjct: 174  YSVNATNSVGRATSTAELLVQGE 196



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 35/116 (30%), Positives = 55/116 (47%)

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            V +    +VT  A++             ++ L+++ V EG+    +  I+    PT+ W 
Sbjct: 872  VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 931

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            RE   I  + DFQ+  +   A L+I   + ED+G FTC A   AG V TS  L V+
Sbjct: 932  REDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 55/229 (24%), Positives = 92/229 (40%), Gaps = 16/229 (6%)

Query: 2122  KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
             +EG    + C++E   D    + W+   +++    +Y  T++ G   L +      D GT
Sbjct: 25083 EEGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 25141

Query: 2182  YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISP 2241
             Y CK  N  GE  +   L V G R  + D      ++KI++        R +       P
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKR--------RTDTMRLLERP 25192

Query: 2242  PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ---SAARFHITFDFG 2298
             P F   L   T  + G+   F   +  VH P   + +Y +G+ ++   +  ++    D G
Sbjct: 25193 PEFTLPLYNKT-AYVGENVRFGVTI-TVH-PEPHVTWYKSGQKIKPGDNDKKYTFESDKG 25249

Query: 2299  YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
                L I     +D  EY+V A N  G  +    +TVT        + RP
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 25298



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 85/402 (21%), Positives = 160/402 (39%), Gaps = 50/402 (12%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            K ++   ++E E A F+ E     +P  +W  +   ++ SP  +I     K  L +R+V 
Sbjct: 4904 KPIEDVTIYEKESASFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLRKVK 4962

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            ++ +      A N    A  +A L V+E         +   F +  ++V V   +  R +
Sbjct: 4963 LDQAGEVLYQALN----AITTAILTVKE---------IELDFAVPLKDVTVPERRQARFE 5009

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
              +T  +  +V W K      PDI    ++    + ++         GK   + IN   +
Sbjct: 5010 CVLT--REANVIWSKG-----PDI----IKSSDKFDIIA-------DGKKHILVIN---D 5048

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
            ++ D E V +      K   +        + + PL+D+ V EG+   F C++  + +  V
Sbjct: 5049 SQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVV 5108

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
             W+K D  +  S+   +S     + L + E   +D    K         ++  A+LKV +
Sbjct: 5109 -WFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKA----QVKELSSTAQLKVLE 5163

Query: 4715 PDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
             D     P  T  L D    E      K +++  +   ++W ++G  I  +P + +  +G
Sbjct: 5164 AD-----PYFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSPKYSIKADG 5216

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATT--AAGQVETSAKLVVKSK 4813
               +L I     +D G + C   T      V   A+L+   K
Sbjct: 5217 LRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEK 5258



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 81/358 (22%), Positives = 141/358 (39%), Gaps = 54/358 (15%)

Query: 3571  ENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLY 3630
             E     + C+ I   D S +V W+   + L    + +   + G  IL +  + + D G Y
Sbjct: 25084 EGGHVKYVCK-IENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 3631  TCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDE 3690
              CK  N +GE +   +L VKG + +        + +   + I++  +T+   E       
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVY-----DYYCRRTMKKIKRRTDTMRLLER------ 25191

Query: 3691  KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTL- 3747
                PP FT+ +  N     G  V F   +    +P   + W+ +G+    G   + +T  
Sbjct: 25192 ---PPEFTLPLY-NKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFE 25245

Query: 3748  NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEK 3807
             +D G   L I+ +   D  EYT  A NK+G  +      C AK  + L            
Sbjct: 25246 SDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS------CKAKLTVTLHPP--------- 25290

Query: 3808  IKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR 3867
                         P +  +    P F   + +   +E + V FE RV     P L+  W +
Sbjct: 25291 ------------PTDSTL---RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEK 25333

Query: 3868  NGKLLPSGHRYRTVYD-MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
             +G+ L  G     +++ + + +L I     ED+G Y   A N  G    +A +  ++L
Sbjct: 25334 DGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERL 25391



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 92/397 (23%), Positives = 156/397 (39%), Gaps = 53/397 (13%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            +K +    V E ++A FE E    P    +W R+   +  + + +  +   K  LII   
Sbjct: 2577 SKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAAT 2635

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             ++D   +      +  T+K SA L VE  +              T +N+ VT  Q    
Sbjct: 2636 KLDDIGEYTY----KVATSKTSAKLKVEAVK-----------IKKTLKNLTVTETQDAVF 2680

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              ++T      V W+KNG  ++ + +  I  +   Y+L I      D   Y         
Sbjct: 2681 TVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGA 2740

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR   E V                     +II+  KD    E   + F   +    +P 
Sbjct: 2741 SARLHVETV---------------------KIIKKPKDVTALENATVAFEVSVSHDTVP- 2778

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            V+W+  +  IKPS   ++      + L +    P D G+Y  V     G++   AKL V 
Sbjct: 2779 VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFV- 2833

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
                 + L     +++I V E + A F+ +++    P++ WL+ G  I  +  F+++ +G
Sbjct: 2834 -----ETLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG 2887

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                L+I NT  ED+  +    T   G  + SA L V
Sbjct: 2888 KLHQLIIMNTSTEDSAEY----TFVCGNDQVSATLTV 2920



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 83/405 (20%), Positives = 153/405 (37%), Gaps = 68/405 (16%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+ + +++  TV+  +  RF   +  +  PK  I WY+  +LL +G + +         
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPK--ISWYKEEQLLSTGFKCK--------- 3240

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
                  +  D  EY    +  F ED   A  +C+   D         G+  + A   +E 
Sbjct: 3241 ------FLHDGQEYTLLLIEAFPED--AAVYTCEAKNDY--------GVATTSASLSVEV 3284

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
                   EV   + ++       PP  +T +Q  T   E +  +F+C+   V   ++KV 
Sbjct: 3285 P------EVVSPDQEM----PVYPPAIITPLQD-TVTSEGQPARFQCR---VSGTDLKVS 3330

Query: 4009 WFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W+   K +   +RF  +  F     +     YPED G Y   A+N  G   + A +    
Sbjct: 3331 WYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3389

Query: 4068 KPGIVYD---SQLPKHMKSIE----------------KIREMEASWQVTPEQVV-----E 4103
               I+++    ++   MK                   ++ ++  + ++  E  V     +
Sbjct: 3390 PESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFD 3449

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
              K    P+F+       +  G+ A     V G PKP++ W  NG  +   + YK  +DG
Sbjct: 3450 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3509

Query: 4164 MYH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR 4207
              H   I  T+  D G+   +             LK+  + + ++
Sbjct: 3510 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK 3554



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 79/290 (27%), Positives = 112/290 (38%), Gaps = 26/290 (8%)

Query: 4481  FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG- 4539
             F    EN GG ++ S   + E    +    I  P F    +N+NV       L  KVTG 
Sbjct: 24400 FRVKCENLGGESEWSE--ISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGH 24457

Query: 4540  TKPIDVYWLKNGKKVQPD-IRNKILEEDGTYTLLILEAYPQDSGK-YECVAINSAGEARC 4597
              KPI V W + GK++  D ++ +I E  G Y  LI+ +   D    Y+  A N  G    
Sbjct: 24458 PKPI-VKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSG 24516

Query: 4598  DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
              A   V +PA    PK            +E +       G+ +       GKP P + W 
Sbjct: 24517 TASLEVEVPAKIHLPK-----------TLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ 24565

Query: 4658  KGDKLIKPSKYFQMSRTADEYTLRISEAFP-EDEGDYKCVAYNSAGRVTVAAKLKVTQ-P 4715
             KG  LI  + ++Q+  T    +L        +D G Y   A N  G      +L V   P
Sbjct: 24566 KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVP 24625

Query: 4716  DQADNLPALTPLRDIV-VYEGQPA-----QFKTQITSKIKPTIQ-WLREG 4758
             D    +      RD V +   +PA     +    I  K   T + WLR G
Sbjct: 24626 DPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG 24675



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 78/342 (22%), Positives = 121/342 (35%), Gaps = 19/342 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN-K 470
            + RV   P P   +   D    D Y  +  V       + IT  T+ +        R  K
Sbjct: 822  ETRVRAEPTPLPQFPFADTP--DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAK 879

Query: 471  SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530
              ETA   R+    +  V  P  V     + V EGE V L     G P+P +TW ++   
Sbjct: 880  VTETA---RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQ 936

Query: 531  IIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQ 590
            I  + + +I    G + L I  A A D+  + C+A N AG+ +T   L           +
Sbjct: 937  IESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL---AVQVSEEFE 993

Query: 591  KRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAME 650
            K                       +           PGE       P FI        +E
Sbjct: 994  KETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEP----AAPYFITKPVVQKLVE 1049

Query: 651  GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--RFGYISLDMLSLNIQDSGE 708
            GG + F  ++   G+P   + W K+G  +    R+   +  + G   L +      D+GE
Sbjct: 1050 GGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1107

Query: 709  YTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQL 750
            YT    +  G  ET A   +   A  E   +  + + Y  Q+
Sbjct: 1108 YTIVVRNKHG--ETSASASLLEEADYELLMKSQQEMLYQTQV 1147



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 52/221 (23%), Positives = 90/221 (40%), Gaps = 27/221 (12%)

Query: 265   PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL---INSNKHEIITTHNHT 321
             PP+      N     G + +F V ++ +P P VTW+K+GQ++    N  K+   +     
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 25251

Query: 322   TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
              L + +    D   YT++A N                   Y +D     +T T       
Sbjct: 25252 QLTINSVTTDDDAEYTVVARN------------------KYGEDSCKAKLTVTLHPPP-- 25291

Query: 382   RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
                 ++  L P F ++  + +  EG+   F+ RV+G P P + W  + + +    N +I+
Sbjct: 25292 ----TDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII 25347

Query: 442   VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
                   +AL I +    D+G     A N +G T+ Q  L V
Sbjct: 25348 HEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 8/161 (4%)

Query: 357  SPTESYVQDQRSQYITDTQQRETEE-RIE--ISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
            S T + V+++R + +   + + TE  R+   +      P  V   ++  V EG+    +C
Sbjct: 859  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
             ++G P P VTW+  D QI    + +I   +SG   LMI      DSG  TC A N++G 
Sbjct: 919  HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977

Query: 474  TAFQCRL--NVIEKEQVVAPKFVERFSTLNVR--EGEPVVL 510
             +  C L   V E+ +       E+F+T   R  E   VV+
Sbjct: 978  VSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVM 1018



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 1/121 (0%)

Query: 451   MITNVTLSDSGVVTCVARNKSGET-AFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
             +ITN+T  +  +   VA N+ G +      + ++ K+ V+ P     FS+ +V+ G+ + 
Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16751

Query: 510   LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +     G P P ITW KDG+P+     + +      +TL I      D   Y  T  NV 
Sbjct: 16752 IEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVV 16811

Query: 570   G 570
             G
Sbjct: 16812 G 16812



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 82/307 (26%), Positives = 134/307 (43%), Gaps = 46/307 (14%)

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
            ++ K+ E   A F+ ++S  P   V W K+ Q L  +++ +I        L + +T+ SD
Sbjct: 3019 KDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 3077

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
            +G YT++A    G  V++  L VE                D + R  ++ +++ EK  A 
Sbjct: 3078 AGKYTVVA----GGNVSTAKLFVEG--------------RDVRIRSIKKEVQVIEKQRAV 3119

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
               +V +D DV              +   E+ + + +R       HK +V E   H + I
Sbjct: 3120 VEFEVNED-DVDAHWY---------KDGIEINFQVQER-------HKYVV-ERRIHRMFI 3161

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +    SD+G  T VA RN+S  T +   +N  E  QV+     +    + V+ G+P    
Sbjct: 3162 SETRQSDAGEYTFVAGRNRSSVTLY---VNAPEPPQVL-----QELQPVTVQSGKPARFC 3213

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            A   G P P+I+W K+   +    + +   DG   TL +  A   DAA Y C A+N  G 
Sbjct: 3214 AVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGV 3273

Query: 572  TATRARL 578
              T A L
Sbjct: 3274 ATTSASL 3280



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 52/229 (22%), Positives = 96/229 (41%), Gaps = 9/229 (3%)

Query: 2795  CNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVSLDITHTYEEDSGIYTCKATN 2852
             C VE S     ++ W+ + K L     ++  +  D +Y  L I +  E D G Y C+ + 
Sbjct: 26240 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTY-ELKINNLTESDQGEYVCEISG 26298

Query: 2853  SKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPE 2912
               G++ T+        K+I+            ++ ++  E+ + +   P  P+    KP 
Sbjct: 26299 EGGTSKTNLQFMGQAFKSIHEKVSKISETK--KSDQKTTESTVTRKTEPKAPEPISSKP- 26355

Query: 2913  WIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLD 2972
              +I    +   V    +  +  V+   +P     W  +GK + QG ++KL+ D G   L+
Sbjct: 26356 -VIVTGLQDTTVSSDSV-AKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413

Query: 2973  LVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS-KDNLIERTQHPKGTE 3020
             +      DSG+YTC   N  G   +S  +   + KD   ++    K +E
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSE 26462



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 35/105 (33%), Positives = 56/105 (53%), Gaps = 2/105 (1%)

Query: 255  EIDRS-LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE 313
            E D S L  +  P    KP + K  EG  A+F +++ G P P   WF +GQ+++N   H+
Sbjct: 1399 ETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK 1458

Query: 314  IITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            ++   + T +L +     SDSG +T++A+N  G    S  L VE+
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1503



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 48/196 (24%), Positives = 81/196 (41%), Gaps = 13/196 (6%)

Query: 373  DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
            D Q    +    +  K      ++  +D  VT G+   FDC ++    P V W++  +++
Sbjct: 5680 DFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKL 5738

Query: 433  RDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
                + K++    G  H L + +V L D+G V   A++      F+   N+  KE  V  
Sbjct: 5739 EP--SDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD------FKTHANLFVKEPPV-- 5788

Query: 492  KFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551
            +F +      V EG   VL    V     ++ W K+G  I+ + +  I  DG    L I 
Sbjct: 5789 EFTKPLEDQTVEEGATAVLECE-VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIH 5847

Query: 552  RAKASDAAWYQCTAQN 567
                 D   Y C A++
Sbjct: 5848 DCTPEDIKTYTCDAKD 5863



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 39/121 (32%), Positives = 56/121 (46%), Gaps = 4/121 (3%)

Query: 4596  RCDAECVVSLPATKDKPKPQT-KAANAPPEIIEPLKDK---IVAEGQAIEFSCKIVGKPL 4651
             R  A   V++    +   P T  A N PP I   +  K    V  G  +     + GKP+
Sbjct: 12768 RAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPM 12827

Query: 4652  PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
             PTV W K   L+KP++  +M+   +  TL +     +D GDY   A NS+G  +   KLK
Sbjct: 12828 PTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLK 12887

Query: 4712  V 4712
             V
Sbjct: 12888 V 12888



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 66/299 (22%), Positives = 116/299 (38%), Gaps = 22/299 (7%)

Query: 4514  PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
             P  TL  ++  V  GQ  R    V      +V W  NG ++Q   +       G  TL I
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936

Query: 4574  LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL-KDK 4632
             L+ +  DSG Y  V  N  GEA   A   V+          Q +    P  +   L + +
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKGEASDYATLDVT-GGDYTTYASQRRDEEVPRSVFPELTRTE 25995

Query: 4633  IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
               A     + S       +  V+    +     S Y + S +A+  +  + E   E++  
Sbjct: 25996 AYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSY-EHSASAEMKSAALEEKSLEEKST 26054

Query: 4693  YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
              + +      + T+AA++ +T+P            R + VYEG+ A+F      +  PT+
Sbjct: 26055 TRKI------KTTLAARI-LTKP------------RSMTVYEGESARFSCDTDGEPVPTV 26095

Query: 4753  QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              WLR+G ++  +   Q+      +   I +    D G ++     + G+ E    L ++
Sbjct: 26096 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 13/141 (9%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFF 962
            +TQ P F  P++  + + EG  A FEA +   G     V W +DG+ +  S+   +   F
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            + G   LTI +VT  ++G Y+ +A N  GQAT++A L +       AE+  P  ++++Q 
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK------AETAPPNFVQRLQS 112

Query: 1023 LEDASRYSKRTEEEVKITQKP 1043
            +    R   +   +V++T  P
Sbjct: 113  M--TVRQGSQVRLQVRVTGIP 131



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 3/115 (2%)

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
            Q  ST   + + + +PP FV  L+  T V +G     + +V  +  P   ++FY +G  +
Sbjct: 88   QATSTAELLVKAETAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEI 144

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
            QS+  F I+ +    SL I    PED+G YSV A N++G  TS   + V  +  +
Sbjct: 145  QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 68/300 (22%), Positives = 122/300 (40%), Gaps = 40/300 (13%)

Query: 4442 IKWYR--ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLV 4499
            +KW +  E  P  N   +++  +  K +L I+     D   +   A    G  K  A L+
Sbjct: 6267 LKWTKNGEEVPFDNRVSYRVDKY--KHMLTIKDCGFPDEGEYIVTA----GQDKSVAELL 6320

Query: 4500 VEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIR 4559
            + E          P  F    ++  VT         +++  K  +V W +NG++++   +
Sbjct: 6321 IIE---------APTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKK 6370

Query: 4560 NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
             K  E+DG+   LI++                  + R D EC  +      K + +    
Sbjct: 6371 YKF-EKDGSIHRLIIK------------------DCRLDDECEYACGVEDRKSRARLFVE 6411

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
              P EII P +D + A G  + F  ++  K    VQW + + ++      QM      + 
Sbjct: 6412 EIPVEIIRPPQDILEAPGADVVFLAEL-NKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHR 6470

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGR--VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
            L+I +  P D+G+Y+ +A +   R  + +AA  K+   DQ   +    PL  +V Y+  P
Sbjct: 6471 LQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYP 6530



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 101/468 (21%), Positives = 178/468 (38%), Gaps = 60/468 (12%)

Query: 3992  KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRAT 4051
             K+ C++    D + +V W+F  + L +  ++   Y+ G   +    +   D G Y C+  
Sbjct: 25089 KYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 25147

Query: 4052  NLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPP 4111
             N YG D + A +   G    VYD    + MK I++        +    +++E      PP
Sbjct: 25148 NDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKR--------RTDTMRLLER-----PP 25193

Query: 4112  VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR-YKLTYD---GMYHF 4167
              F       T   GE  RF   +T HP+P V W  +G  I  G    K T++   G+Y  
Sbjct: 25194 EFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQL 25253

Query: 4168  DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRT 4227
              I      D  +  V+             L V          L    RP +         
Sbjct: 25254 TINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTL----RPMF--------- 25300

Query: 4228  ETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQ---QSVKRKKNEEYYNKLQEL 4284
                 ++     +  + Q V     E++   I  P  +W+   Q +    N E  +  + L
Sbjct: 25301 ----KRLLANAECQEGQSVCF---EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH--EGL 25351

Query: 4285  ENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQ----RYEDNLDQTEEVTEQRVQKK 4340
             +   +     L E T  Y +       +T  ++  Q    RY+    +++E  E+ VQK+
Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25411

Query: 4341  VTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTE-TTEIEHKAQTQER 4399
             + +  R+ +    T       VAK+   +  V+    ++ K    E   EIE K   +ER
Sbjct: 25412 IDKTLRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEK--KEER 25469

Query: 4400  VVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
              +  P    +P    +K +   + E ++ +  V     P+  +KWY++
Sbjct: 25470 KLRMPYDVPEP----RKYKQTTIEEDQRIKQFV-----PMSDMKWYKK 25508



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 2/106 (1%)

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            + PP+     +NV V  G+ V L+  ++G     V W +   +++  I  +I  + G   
Sbjct: 894  VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 953

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
            L+I EA+ +DSG++ C A+N AG       C +++  +++  K  T
Sbjct: 954  LMIREAFAEDSGRFTCSAVNEAGTV--STSCYLAVQVSEEFEKETT 997



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 105/508 (20%), Positives = 194/508 (38%), Gaps = 58/508 (11%)

Query: 4306 GDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQ 4365
            G+ +TS  +  +     +   DQT   +++ V +     P      E    GK + +   
Sbjct: 2561 GENITSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANP--DSKGEWLRDGKHLPLTNN 2618

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
             +++ +    + I       +  E  +K  T +   +  V+  K     K ++   V E 
Sbjct: 2619 IRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVK---IKKTLKNLTVTET 2675

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            + A F VE     +  ++W +    ++++  + I    T   L I+   + D +V+    
Sbjct: 2676 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGF-- 2733

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
              R G    SA L VE  +      I  P      +N  V     V  DT       + V
Sbjct: 2734 --RLGRLGASARLHVETVKI-----IKKPKDVTALENATVAFEVSVSHDT-------VPV 2779

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W     +++P  +++++ E   + L++    P D+G+Y  V     G+  C A+  V  
Sbjct: 2780 KWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVE- 2834

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                               I + +K+  V E +   F C++    +P++ W K    I+ 
Sbjct: 2835 ----------------TLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEM 2877

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+ F++      + L I     ED  +Y  V     G   V+A L VT       +   +
Sbjct: 2878 SEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGNDQVSATLTVTP------IMITS 2927

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             L+DI   E     F+  +  +   + +WL+ G  I  T   QM  +     L I N + 
Sbjct: 2928 MLKDINAEEKDTITFEVTVNYE-GISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHF 2986

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             D   +    T  AG+  ++A L V+++
Sbjct: 2987 GDAADY----TFVAGKATSTATLYVEAR 3010



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 35/146 (23%), Positives = 65/146 (44%), Gaps = 4/146 (2%)

Query: 391   APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
             AP   K  +D     G+  +  C++ GRP P++ W+   +++     +K + ++   H L
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYK-MSSDGRTHTL 24093

Query: 451   MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
              +      D GV TC+A N+ GE     +L +++      P +  +        G  + L
Sbjct: 24094 TVMTEEQEDEGVYTCIATNEVGEVETSSKL-LLQATPQFHPGYPLKEKYYGA-VGSTLRL 24151

Query: 511   NARAVGTPTPRITWQKDGVPIIPNPE 536
             +   +G P P +TW   G  ++ N E
Sbjct: 24152 HVMYIGRPVPAMTW-FHGQKLLQNSE 24176



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIF 823
           T+Q P F +PLQ +  L EG  A FEA ++    P   V W++DG+ I+ S+   +   F
Sbjct: 2   TTQAPTFTQPLQSVVVL-EGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           + G   L I  +   ++G Y+++A N  G+A STA + V A +
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 3/94 (3%)

Query: 4622  PPEI-IEP-LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             PP I ++P  KD IV   G++ +    I GKP+PT+QW KGD+ +  +   ++  T    
Sbjct: 16043 PPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT 16102

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +L + +A   D G+Y   A N AG  +V   +KV
Sbjct: 16103 SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16136



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 3/107 (2%)

Query: 468   RNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRITW-- 524
             +N+ GE+ +     V+ KE +  P    + S  L V+ G+ + L A   G P P + W  
Sbjct: 11681 KNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTK 11740

Query: 525   QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              KD   +  +P ++I T   +S   + +AK SD   Y  TA N AGS
Sbjct: 11741 DKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGS 11787



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 82/372 (22%), Positives = 149/372 (40%), Gaps = 58/372 (15%)

Query: 2784  VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
             V +EG ++ + C +E + D + ++ W+F  + L +  +Y+ T++     L +    + D 
Sbjct: 25081 VGEEGGHVKYVCKIE-NYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDD 25139

Query: 2844  GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
             G Y CK  N  G  ++   L   G + +Y    +   +   +   + +  RL +  RP  
Sbjct: 25140 GTYRCKVVNDYGEDSSYAELFVKGVREVY---DYYCRRTMKKIKRRTDTMRLLE--RP-- 25192

Query: 2904  PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQG---SRF 2960
                    PE+ +P+  +   V G+  ++   V     P+  + WY +G+ ++ G    ++
Sbjct: 25193 -------PEFTLPLYNKTAYV-GE--NVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKY 25242

Query: 2961  KLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTE 3020
                SD G   L +  V   D   YT  A NK GE        C +K   +  T HP  T 
Sbjct: 25243 TFESDKGLYQLTINSVTTDDDAEYTVVARNKYGED------SCKAK---LTVTLHPPPT- 25292

Query: 3021  GLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSM 3080
                     + +LR              P F  +  +  +  EGQ   +E  +  +G    
Sbjct: 25293 --------DSTLR--------------PMFKRLLAN-AECQEGQSVCFEIRV--SGIPPP 25327

Query: 3081  VIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
              ++W  +G+ +     I  ++       L I  T   D+G Y   ATN  G       L+
Sbjct: 25328 TLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQ 25387

Query: 3140  CVDKSKGQKPRF 3151
              V++ + +K  F
Sbjct: 25388 -VERLRYKKQEF 25398



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 72/337 (21%), Positives = 133/337 (39%), Gaps = 44/337 (13%)

Query: 2256  EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEY 2315
             EG    + C++E  +D + ++ +Y   + L+++ ++ IT++ G   L ++     D G Y
Sbjct: 25084 EGGHVKYVCKIEN-YDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 2316  SVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKI-RELESAEPFKRPEIPEPVTRQ 2374
               K +N  G  +S   + V     +     R   ++KI R  ++    +RP         
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVYDYYCR-RTMKKIKRRTDTMRLLERP--------- 25192

Query: 2375  RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
              P FT PL N      G+   F   +    +P   V W+++ + I+      K + F   
Sbjct: 25193 -PEFTLPLYN-KTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDN-DKKYTF--- 25244

Query: 2435  SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494
                     + D+G+Y    +++  +              +    ++ E   K +     H
Sbjct: 25245 --------ESDKGLYQLTINSVTTDDDAEYT--------VVARNKYGEDSCKAKLTVTLH 25288

Query: 2495  ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
                   P     +P+F ++L   +E  EGQ   +E RV  +  P+L+  W  +G  L +G
Sbjct: 25289 P----PPTDSTLRPMFKRLLAN-AECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLG 25341

Query: 2555  SRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   H+   +  L I   +  D G Y   A N AG
Sbjct: 25342 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 25378



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 2/88 (2%)

Query: 2776  FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
             FIS   +    EG N+ F C +  S +P+ +IEWF NN P+   +    +   +  SL+I
Sbjct: 26639 FISQPRSQNINEGQNVLFTCEI--SGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26696

Query: 2836  THTYEEDSGIYTCKATNSKGSATTSGSL 2863
              +    DSG YT KA N +G  + + SL
Sbjct: 26697 RNASVSDSGKYTIKAKNFRGQCSATASL 26724



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 4722 PALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMIHEGNNAVL 4778
            P  T PL+ +VV EG  A F+  I+    P + W R+G +I  +  P  Q+      A L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             I    + ++G ++ +AT  +GQ  ++A+L+VK++T
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 11/171 (6%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F++   D  V E +M RF+C ++ R   +V WF +  +I+    + I +++     L+I
Sbjct: 5878 EFLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDI-ISKGAVRILVI 5935

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
                L D    +C  R  +  T+    L V+E+E V    F +  + + V E + + L  
Sbjct: 5936 NKCLLDDEAEYSCEVR--TARTSGM--LTVLEEEAV----FTKNLANIEVSETDTIKLVC 5987

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
              V  P   + W K    II      I T+G    L I  A   DA  Y C
Sbjct: 5988 E-VSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 6037



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 1/105 (0%)

Query: 467   ARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
             A+N+ G     Q  + VI K+ V+ P F   F+T  V  GE + ++   +G PTP +TW 
Sbjct: 15626 AQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH 15685

Query: 526   KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             KD VP+     +   +    S L I  A   D   Y     N AG
Sbjct: 15686 KDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 15730



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 42/169 (24%), Positives = 71/169 (42%), Gaps = 4/169 (2%)

Query: 1520  RAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPI 1579
             R+ + V ++    R    +  DI    ++     + Q   +R KY            AP 
Sbjct: 25820 RSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSER-KYEVLSQQPFTLDHAPR 25878

Query: 1580  CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDI 1639
              T  +++  +  GQ   F   +   S  T +V+WYHN   L+  S+   TN  G + L+I
Sbjct: 25879 ITLRMRSHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936

Query: 1640  MSCLPEDSGTYTCRAINALGEAVT-SGIAIVHSKKSIYLESQHEGALPR 1687
             + C  +DSGTY     N  GEA   + + +     + Y   + +  +PR
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPR 25985



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 5/125 (4%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            +I  K    + TE E         + GP     PP F K+++P R  +   A FE    G
Sbjct: 3545 KINSKGEGHKDTETESAVAKSLEKLGGPC----PPHFLKELKPIRCAQGLPAIFEYTVVG 3600

Query: 4437 EPLPLIKWYRENFPIKNSPDFQ-IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            EP P + W++EN  +  S  +  IH  +     I+     EDS ++   AEN  G + C+
Sbjct: 3601 EPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCA 3660

Query: 4496 ANLVV 4500
            A L+V
Sbjct: 3661 AELLV 3665



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 54/186 (29%), Positives = 86/186 (46%), Gaps = 14/186 (7%)

Query: 388  KALAPQFVKVCQDRDVTE----GKMTRFDCRVTGRPYPEVT-WFINDRQIRDDYNHKILV 442
            KA+  +FVK  +D  +TE    G    F+C V+  P   +T W  +   IR+   H+ + 
Sbjct: 4614 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIA 4671

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
             +  +  L I +V LSD+G  TCV R  + E     +L V+E+  V   K +E    + V
Sbjct: 4672 -DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKL-VVEELPVRFVKTLE--EEVTV 4727

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWY 561
             +G+P+ L+          + W+KDG  ++  P  +     G    L I  A  +DA  Y
Sbjct: 4728 VKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTY 4785

Query: 562  QCTAQN 567
              T +N
Sbjct: 4786 TVTVEN 4791



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 48/200 (24%), Positives = 80/200 (40%), Gaps = 3/200 (1%)

Query: 4614  PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMS 4672
             P++      P   E L++  V         CK+ G P P V+WY+ G ++I     +++ 
Sbjct: 24422 PKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQ 24481

Query: 4673  RTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
                  Y  L I+    +D   Y+  A N  G V+  A L+V  P +      L  +  + 
Sbjct: 24482 EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVH 24541

Query: 4732  VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE-EDTGT 4790
                G+    K   + K  P I W +   LI     +Q+I   +   L+  N  E +D G 
Sbjct: 24542 ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGF 24601

Query: 4791  FTCRATTAAGQVETSAKLVV 4810
             +   A    G  + + +L V
Sbjct: 24602 YVVCAKNRFGIDQKTVELDV 24621



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++  V +G  V L+  +T +  PT  V++Y +G  +Q    F+ + +    +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             I  AY ED+GTY   ATN+VG A +T+ + V  +
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765
            TQAP FT P++ + V E   A FEA +   G P   V W R+G  I  S        F  
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSD 60

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            G   L +  V   +SG Y+ +A N  G+A +++ L V+++ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 45/187 (24%), Positives = 91/187 (48%), Gaps = 15/187 (8%)

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
            E+++P++D  + E ++  F  +I    +P  QW    +L++PS   ++     +  L + 
Sbjct: 4901 ELLKPIEDVTIYEKESASFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLR 4959

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
            +   +  G+   V Y +   +T A  L V + +    L    PL+D+ V E + A+F+  
Sbjct: 4960 KVKLDQAGE---VLYQALNAITTAI-LTVKEIE----LDFAVPLKDVTVPERRQARFECV 5011

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            +T +    + W +   +I  +  F +I +G   +L+I ++  +D G +T       G+ +
Sbjct: 5012 LTREAN--VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAE---VEGK-K 5065

Query: 4804 TSAKLVV 4810
            TSA+L V
Sbjct: 5066 TSARLFV 5072



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 52/230 (22%), Positives = 93/230 (40%), Gaps = 15/230 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+T G   +     ++++D    Y        T+ ++++ E  LA +F+   Q+ ++ EG
Sbjct: 6013 ILTEGRKRILVIQNAHLEDA-GNYNCRLPSSRTDGKVKVHE--LAAEFISKPQNLEILEG 6069

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            +   F C ++   +P V W  +D+ +     + ++  +     L++ + TL D G    +
Sbjct: 6070 EKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIA-DGKKRVLVVKDATLQDMGTYVVM 6127

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
                 G       L VIEK ++V P          V+E + VV N   V T   +  W +
Sbjct: 6128 V----GAARAAAHLTVIEKLRIVVP-----LKDTRVKEQQEVVFNCE-VNTEGAKAKWFR 6177

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
            +   I  + +  I       TL I  A   D A Y  +  N  G     A
Sbjct: 6178 NEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSA 6227



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 1/93 (1%)

Query: 482   VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             VI K+  + P     F+T +++ GE + +    +G P P I+W KDG P+     + +  
Sbjct: 17806 VIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEE 17865

Query: 542   DGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
                ++ L I      D   Y  TA N AG TAT
Sbjct: 17866 TATSTVLHIKEGNKDDFGKYTVTATNSAG-TAT 17897



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%)

Query: 266   PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
             P I ++ ++   + G  AQ   Q+ G P P + W++ G+ LI S K+++ +     TL V
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095

Query: 326   RNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
                ++ D G YT +A N  G + TS  L +++
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 44/186 (23%), Positives = 77/186 (41%), Gaps = 8/186 (4%)

Query: 3054  FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGT 3113
             F   + I+EGQ    +A++    D    ++W  NG  +  S   R   +     L I   
Sbjct: 26547 FSTQMSINEGQRLVLKANIAGATD----VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQA 26602

Query: 3114  KTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173
                D G  +C +  K G  +    L  + K     P F +  ++ + + +GQ+  F C +
Sbjct: 26603 SHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDAPAFISQPRS-QNINEGQNVLFTCEI 26660

Query: 3174  VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                 +P  +IEW+ N  P+  S+ +          L+I      DSG+Y  +A N  G+ 
Sbjct: 26661 S--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQC 26718

Query: 3234  FTRATI 3239
                A++
Sbjct: 26719 SATASL 26724



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 1/92 (1%)

Query: 67   GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
            G P PP F +  K  R AQG  A FE  + G P P V+W ++   L     Y++ +N   
Sbjct: 3570 GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHN-PN 3628

Query: 127  GDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            G  + ++      D G Y C A N  GE+ C+
Sbjct: 3629 GSGTFIVNDPQREDSGLYICKAENMLGESTCA 3660



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 125/638 (19%), Positives = 243/638 (38%), Gaps = 50/638 (7%)

Query: 1174 KSKPV-FVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            K  PV F +PL +   V EG    LEC +        +V+WF NG  +    +++   D 
Sbjct: 5784 KEPPVEFTKPLEDQT-VEEGATAVLECEVSR---ENAKVKWFKNGTEILKSKKYEIVAD- 5838

Query: 1233 GFVALDIIH-ATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ---NEQAIEQI 1288
            G V   +IH  T  D   YT  A +   S + + +   +E    +TD Q    E A  + 
Sbjct: 5839 GRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFEC 5898

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
            +L  + A+  K  ++   + +  ++         +   N   +C L          E+ C
Sbjct: 5899 ELSRENAK-VKWFKDGAEIKKGKKYDIISKGAVRILVIN---KCLLDD------EAEYSC 5948

Query: 1349 NGKPIKTGHRFRPAYEFDYVALDL--LSVYPEDSGVYTCQATNQLGEAVTSCALRVI--- 1403
              +  +T        E      +L  + V   D+    C+ +    E +       I   
Sbjct: 5949 EVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIET 6008

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYK------KTDIIDESVTIKPRFVTRPKSIENVI 1457
             + +++ E +    + +  +LED   Y       +TD   +   +   F+++P+++E ++
Sbjct: 6009 GRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLE-IL 6067

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EG+   F C    ++  +  V+W ++ + +  G ++  I D     L + D   +D G Y
Sbjct: 6068 EGEKAEFVCS---ISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 6124

Query: 1518 TCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
                V +VG    +  LT      IV   ++    EQ +V+ +               + 
Sbjct: 6125 ----VVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEE 6180

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSD-ATLKVE-WYHNNKPLKSGSR-FTETNNFGF 1634
             I  +S K + +++        R   + D A   V    H  + +KS +    E  +   
Sbjct: 6181 AIFDSS-KYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRI 6239

Query: 1635 V-ALDIMSCLPEDSGTYTCRA--INALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN-Q 1690
            V  L  +  + + S T+ C+   +N   +   +G  +    +  Y   +++  L   +  
Sbjct: 6240 VEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCG 6299

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ-AAHFEARLI--PVGDPKLRVEWL 1747
              D  +Y   + QD+ + +  +   P + +   E+Q    F+  +    +   K  V+W 
Sbjct: 6300 FPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWY 6359

Query: 1748 RNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785
            RNG  I+   +     D     L +K    +D   Y C
Sbjct: 6360 RNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC 6397



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 4/137 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH--EIITTHNHTTL 323
           P   Q  ++  + EG+ A F+  +SG P P V+WF++GQ +  S     +I  +     L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +    K++SG Y+L A N +G   ++  L V++ T      QR Q +T  Q   ++ R+
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQ--GSQVRL 123

Query: 384 EISEKALAPQFVKVCQD 400
           ++    +    VK  +D
Sbjct: 124 QVRVTGIPTPVVKFYRD 140



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 30/98 (30%), Positives = 55/98 (56%), Gaps = 2/98 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L ++   +G+ V L+ R+   G  T  V+++ +G  I++   F+ + E D  +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
             +   YPEDSG Y+  ATN +G A ++  L V  ++++
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            E + PIF +   NA  + G  A     + G P P + W      L     Y   ++    
Sbjct: 3453 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD-- 3510

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            D SL+I      DEGEYTC A N YG+ ICS Y++
Sbjct: 3511 DHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLK 3545



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 56/207 (27%), Positives = 87/207 (42%), Gaps = 24/207 (11%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI+W+FNG +L   + +K   D    +L ++     D G YTC A N  G+   S+ 
Sbjct: 3484 PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAY 3543

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            +   SK          +G +  E    +  SL K  G         PP F    K I   
Sbjct: 3544 LKINSKG---------EGHKDTETESAVAKSLEKLGGP-------CPPHFLKELKPI-RC 3586

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSG 3119
            ++G  A +E +++  G+ +  + WF   K +  S     ++   G     +   +  DSG
Sbjct: 3587 AQGLPAIFEYTVV--GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 3644

Query: 3120 TYSCRATNKWGQ----AEISVKLECVD 3142
             Y C+A N  G+    AE+ V LE  D
Sbjct: 3645 LYICKAENMLGESTCAAELLVLLEDTD 3671



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 11/179 (6%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F K  +D+ V EG     +C V+ R   +V WF N  +I     ++I V +     L+I
Sbjct: 5789 EFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEI-VADGRVRKLVI 5846

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             + T  D    TC A  K  +T+  C LNV+        +F+   + L VRE E      
Sbjct: 5847 HDCTPEDIKTYTCDA--KDFKTS--CNLNVVPPHV----EFLRPLTDLQVREKEMARFEC 5898

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              +     ++ W KDG  I    +  I + G    L I +    D A Y C  +    S
Sbjct: 5899 E-LSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTS 5956



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 44/200 (22%), Positives = 81/200 (40%), Gaps = 15/200 (7%)

Query: 1606  DATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG 1665
             D + +V WY   + L++  ++  T   G   L +      D GTY C+ +N  GE  +  
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 1666  IAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAEN 1725
                V   + +Y +      + ++ +  DT +         ++ + P FT+P+ +      
Sbjct: 25158 ELFVKGVREVY-DYYCRRTMKKIKRRTDTMR---------LLERPPEFTLPLYNKTAYVG 25207

Query: 1726  QAAHFEARLIPVGDPKLRVEWLRNGVPIEASN---RLTTMHDFGYVALNMKYVNPEDSGT 1782
             +   F   +     P+  V W ++G  I+  +   + T   D G   L +  V  +D   
Sbjct: 25208 ENVRFGVTI--TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAE 25265

Query: 1783  YTCRAINELGEAVTSSTLFV 1802
             YT  A N+ GE    + L V
Sbjct: 25266 YTVVARNKYGEDSCKAKLTV 25285



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 26/66 (39%), Positives = 37/66 (56%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G+     V +SG P P+VTW     RL  +++  I TT + TTL V+++ + DSG Y L 
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22224

Query: 340   AENPNG 345
              EN  G
Sbjct: 22225 LENTAG 22230



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 2/105 (1%)

Query: 1296  RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
             R    ++  +T  +AP   + + ++ T  G    L C++  VG     ++W+  GK +  
Sbjct: 24021 RTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQ 24078

Query: 1356  GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
               +++ + +     L +++   ED GVYTC ATN++GE  TS  L
Sbjct: 24079 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 4/85 (4%)

Query: 1854  TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
             TKL  G++A   C+I   P P+  ++WY  GK L    +Y+ S+D     L ++T   ED
Sbjct: 24047 TKL--GEAAQLSCQIVGRPLPD--IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQED 24102

Query: 1914  SGEYTCKAINNLGQAVSSIRLNVQS 1938
              G YTC A N +G+  +S +L +Q+
Sbjct: 24103 EGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 3/113 (2%)

Query: 2622  KEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKN 2681
             KE  +    ++ +   +  AP F +  +S + + EGQ+V    ++    +P+ +IEWFKN
Sbjct: 26617 KEGIVKCQYDLTLSKELSDAPAFISQPRSQN-INEGQNVLFTCEISG--EPSPEIEWFKN 26673

Query: 2682  GVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
              + ++  + +  +    + +L I +    DSG YT KA N  G+  +TAS+ +
Sbjct: 26674 NLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 12/160 (7%)

Query: 1792 GEAVTSSTL------FVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQA 1843
            G+ +++STL      F   +A L + +  +  S    ++    S +     ++ V    A
Sbjct: 43   GQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102

Query: 1844 P-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            P  F+ +L   T + +G     + R+   P P   V++Y +G  +QS   ++ S +    
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +L I   Y EDSG Y+  A N++G+A S+  L VQ +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 4/140 (2%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V  G    F C ++    P +R  WF  GR      +    +     +L+I      D
Sbjct: 4346 LEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVD 4403

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAK-RDIVLESQLPQGMSGEKIKELERGRISDAPKEE 3823
             GEYTC+A+N++GS + TA +T +    +  +   LP+     K + + +  +   P+EE
Sbjct: 4404 CGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEE 4463

Query: 3824 PIVSTPPKFITQIKSHTVEE 3843
                  PK + ++K   V E
Sbjct: 4464 E-PKVEPKKLEKVKKPAVPE 4482



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 53/204 (25%), Positives = 83/204 (40%), Gaps = 19/204 (9%)

Query: 3449  DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
             D + +V WY+  + L+   ++    + G  IL +      D G Y C+  N+YGE  + A
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 3509  SMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI 3568
              + V+G R +            T+ KI   +  + T+  L        PPEFT    +  
Sbjct: 25158 ELFVKGVREV-----YDYYCRRTMKKI---KRRTDTMRLLE------RPPEFTLPLYNKT 25203

Query: 3569  LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI---NDFGFVILEIGGVYQR 3625
                  +  F    I V+     V W+ +G+ +  G   K     +D G   L I  V   
Sbjct: 25204 AYVGENVRFGV-TITVHPEP-HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25261

Query: 3626  DAGLYTCKATNRHGEATVSCKLQV 3649
             D   YT  A N++GE +   KL V
Sbjct: 25262 DDAEYTVVARNKYGEDSCKAKLTV 25285



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 4/95 (4%)

Query: 769   RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGY 827
             RP F R L +  E QEG++  FE +++ +  PT++  W KDG+P++    I  I     Y
Sbjct: 25297 RPMFKRLLAN-AECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDY 25353

Query: 828   VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
              +L+I     ED G Y V A N  G     A ++V
Sbjct: 25354 YALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 58/228 (25%), Positives = 97/228 (42%), Gaps = 14/228 (6%)

Query: 352  YLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRF 411
            +L++ +   S  +D     + D   + T + I   E A+  +FVK  QD +V E      
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIV--EGAVV-EFVKELQDIEVPESYSGEL 2240

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V+     E  W+ ND +++ +  + I  +  G   L + +VT  D G  + V   K 
Sbjct: 2241 ECIVSPENI-EGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFVIDGKK 2298

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
                  C+L +  K + +A   ++  S   V EG+ V L  + V   +    W KDG  +
Sbjct: 2299 TT----CKLKM--KPRPIA--ILQGLSDQKVCEGDIVQLEVK-VSLESVEGVWMKDGQEV 2349

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             P+  + I  D  +  L I      DA  Y  T   +  ST+ R  +Y
Sbjct: 2350 QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 100/413 (24%), Positives = 169/413 (40%), Gaps = 43/413 (10%)

Query: 1262 HTSAIVRVIERSDIVTDTQNEQAIEQI-QLLEDAARRTKQVREDITVMQA-PQFSRALHN 1319
            HT+  V + +     + T  + +I+   Q+  +A   + + +  +TV++  P F+  L +
Sbjct: 5472 HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAK--LTVLEGDPYFTGKLQD 5529

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
               VE   V L+C +         V+WF +GK IK         +     L L      D
Sbjct: 5530 YTGVEKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSD 5586

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DTSRYKKTDIIDE 1438
             G YTC      G   TS  L +   +D  ++   P  L  ++ +E +T+R++ T+I ++
Sbjct: 5587 IGQYTCDC----GTDKTSGKLDI---EDREIKLVRP--LHSVEVMETETARFE-TEISED 5636

Query: 1439 SV----TIKPRFVTRPKSIENVIEGQ-H--VHFECKLEPVTD-----SNLKVEWFKNGQP 1486
             +     +K   + +    E   EG+ H  V   C+L+         +N+K       +P
Sbjct: 5637 DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKP 5696

Query: 1487 VTIGHRFRPIHDF----GYVALDIIDLIAEDSGI-YTCRAVNLVGTDEVSCRLTCRSTTD 1541
              IG   RP+ D     G  A    +L  ED  + +  +   L  +D+V  R   +  T 
Sbjct: 5697 RVIG-LLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTL 5755

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
             +R  + E   E +Q+     K H    V E   +    T  L++  ++EG  A  E   
Sbjct: 5756 TLRDVKLEDAGE-VQLTAKDFKTHANLFVKEPPVEF---TKPLEDQTVEEGATAVLE--- 5808

Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
              VS    KV+W+ N   +    ++    +     L I  C PED  TYTC A
Sbjct: 5809 CEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 2/117 (1%)

Query: 4598  DAECVVSLPATKDKPKPQTKAANAPPEIIEP-LKDKIVAE-GQAIEFSCKIVGKPLPTVQ 4655
             +A   +S P+    P         P   ++P  +D IV   G+       + GKPLPT++
Sbjct: 17102 NAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIE 17161

Query: 4656  WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             W +GDK I+ S   ++  T  +  L + +A   D G Y   A N AG  +    +KV
Sbjct: 17162 WLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV 17218



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +Q G D + ++ + G PRP ++W K+G+ L  + +  +  T   T L ++   K D G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885

Query: 337   TLLAENPNGCIVTS-GYLAVESP 358
             T+ A N  G    +   + +E P
Sbjct: 17886 TVTATNSAGTATENLSVIVLEKP 17908



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)

Query: 1709  QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             +AP     MKD+     +AA    ++  VG P   ++W R G  +  S +     D    
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH 24091

Query: 1769  ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
              L +     ED G YTC A NE+GE  TSS L +Q+
Sbjct: 24092 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 49/228 (21%), Positives = 89/228 (39%), Gaps = 15/228 (6%)

Query: 2389  QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448
             +EG    + C+ I   D + +V W+   + +E+S +   T++ G   + +  +   D+G 
Sbjct: 25083 EEGGHVKYVCK-IENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 25141

Query: 2449  YMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKP 2508
             Y C+  N  GE              +  +      MKKI++  +    R  E   EF  P
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVREV-YDYYCRRTMKKIKR--RTDTMRLLERPPEFTLP 25198

Query: 2509  IFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG---SRFRTTHDFGF 2565
             ++ +        + G++  +   +    +P +   WY +G ++K G    ++    D G 
Sbjct: 25199 LYNKT------AYVGENVRFGVTITVHPEPHV--TWYKSGQKIKPGDNDKKYTFESDKGL 25250

Query: 2566  VTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRP 2613
               L INSV  +D   Y   A N+ G                 D  +RP
Sbjct: 25251 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 25298



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 1/102 (0%)

Query: 4404  PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTF 4462
             P   +  P+F + +      E +   FE+   G P P +KW ++  P+   P+ + IH  
Sbjct: 25291 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEG 25350

Query: 4463  STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR 4504
                  L IR    ED+  +   A N  G+  C A+L VE  R
Sbjct: 25351 LDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLR 25392



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%)

Query: 2124  GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
             G    F   V+  + P   + W+HNG +++   +   T+  G + L+IL  + +DSGTY 
Sbjct: 25891 GQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 25948

Query: 2184  CKATNKLGEAVNTCTLKVAG 2203
                TN  GEA +  TL V G
Sbjct: 25949 AVCTNYKGEASDYATLDVTG 25968



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 25/83 (30%), Positives = 42/83 (50%)

Query: 263   VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
             V  P +     +  +Q G D + +V +SG P+P +TW K+G  L  + +  +  + + TT
Sbjct: 16730 VIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16789

Query: 323   LRVRNTQKSDSGHYTLLAENPNG 345
             L ++ T K D G Y +   N  G
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVG 16812



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 93/202 (46%), Gaps = 33/202 (16%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK-HEIITTHNHTTLR 324
            PKI ++ ++  + +G+DA F+V++ G P P   W+KNG ++  S++ +      N   L 
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +R+    DS    + A N          +A E+ + +++  Q  Q IT TQ+ +      
Sbjct: 2092 IRDVTAEDSASIMVKAIN----------IAGETSSHAFLLVQAKQLITFTQELQD----- 2136

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                        V +++D     M  F+C  T  P+ +V W+ +  ++ +   ++ + ++
Sbjct: 2137 -----------VVAKEKDT----MATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSD 2179

Query: 445  SGNHALMITNVTLSDSGVVTCV 466
               H L I  +  SD+   +CV
Sbjct: 2180 RKVHFLSILTIDTSDAEDYSCV 2201



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 40/171 (23%), Positives = 64/171 (37%), Gaps = 9/171 (5%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVV 4500
            + WY EN  + +   F+         L+I +V  ED    +   A N  G    SA L V
Sbjct: 4272 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331

Query: 4501 EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN 4560
             ++          P      + + V  G L +   ++     +   W K G+++    + 
Sbjct: 4332 VKR--------AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4383

Query: 4561 KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
             I       +L IL     D G+Y C A N  G   C A   V++P  + K
Sbjct: 4384 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKK 4434



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 5/195 (2%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
             ET E +++SE  L P  V +    DVT    T    +       ++T ++ + Q +    
Sbjct: 18788 ETTEPVKVSEPPLPPGRVTLV---DVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEK 18844

Query: 438   HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGET-AFQCRLNVIEKEQVVAPKFVER 496
                        A  I+ +T  +  V    A N+ G +   Q  + VI ++  + P     
Sbjct: 18845 WSTCTQVKTLEAT-ISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELP 18903

Query: 497   FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
             F T NV+  E + ++    G P   + W+KDG  +     + + +    ++L I  A   
Sbjct: 18904 FHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKE 18963

Query: 557   DAAWYQCTAQNVAGS 571
             D   Y+    N AGS
Sbjct: 18964 DVGTYELCVSNSAGS 18978



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 1/84 (1%)

Query: 274   NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH-NHTTLRVRNTQKSD 332
             N++ QEG    F++++SG P P + W K+GQ L      EII    ++  L +R+T   D
Sbjct: 25306 NAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPED 25365

Query: 333   SGHYTLLAENPNGCIVTSGYLAVE 356
             +G+Y + A N  G      +L VE
Sbjct: 25366 TGYYRVTATNTAGSTSCQAHLQVE 25389



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 70/271 (25%), Positives = 100/271 (36%), Gaps = 31/271 (11%)

Query: 2339 SIISESQRPEGLEKI--RELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTAH 2395
            SI   + R E  E +  RE +  E  + P   E PVT   P     L+N+  I EG++  
Sbjct: 859  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTP--PTLVSGLKNVTVI-EGESVT 915

Query: 2396 FDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
             +C +     PT  V W+R +  IE S     T   G   + I     ED G + C A N
Sbjct: 916  LECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVN 973

Query: 2456 LLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLT 2515
              G                + ET         +K     +R  E  D        T+   
Sbjct: 974  EAGTVSTSCYLAVQVSEEFEKET-----TAVTEKFTTEEKRFVESRDVVMTDTSLTEEQA 1028

Query: 2516 GPSE--------------LWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            GP E              L EG    +  +V   G+P     W  +GV L  G R++ ++
Sbjct: 1029 GPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSY 1086

Query: 2562 D--FGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +   G   L I+   A+DAG Y     N+ G
Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHG 1117



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 4737 PAQFKTQITSKIKPT--IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            PA F+ ++T    PT  ++WL +G  +      +MI+E     L  G  Y  D+G  TCR
Sbjct: 1673 PAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCR 1732

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            AT   G   TSA L+VK +
Sbjct: 1733 ATNKYGTDHTSATLIVKDE 1751



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 25/72 (34%), Positives = 35/72 (48%)

Query: 4633  IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             I   G  I+    ++G+P PTV W KGD+++K ++      TA    L I+E    D G 
Sbjct: 14579 IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14638

Query: 4693  YKCVAYNSAGRV 4704
             Y   A N  G V
Sbjct: 14639 YPLTARNIVGEV 14650



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 49/204 (24%), Positives = 84/204 (41%), Gaps = 12/204 (5%)

Query: 4411  PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
             P   K+M+       E A+   +  G PLP IKWYR    +  S  +++ +      L +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095

Query: 4471  RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                  ED  V+  +A N  G  + S+ L+++   +        P + L  +      G  
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ------FHPGYPLKEKYYGAV-GST 24148

Query: 4531  VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ--DSGKYECVA 4588
             +RL     G +P+      +G+K+  +  N  +E    YT L+++   +   +GKY+   
Sbjct: 24149 LRLHVMYIG-RPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQL 24207

Query: 4589  INSAGEARCDAECVVSLPATKDKP 4612
              N  G    DA   V +    DKP
Sbjct: 24208 SNVFGTV--DAILDVEIQDKPDKP 24229



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 2/74 (2%)

Query: 2926  GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
             G+   L  Q+  +  PD+K  WY  GK L Q  ++K++SD    TL ++   + D G+YT
Sbjct: 24050 GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 2986  CKAYNKRGEAFTSS 2999
             C A N+ GE  TSS
Sbjct: 24108 CIATNEVGEVETSS 24121



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 53/216 (24%), Positives = 83/216 (38%), Gaps = 17/216 (7%)

Query: 650   EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEY 709
             EGG + +  +IE   D + ++ W    + +E S ++   +  G   L +  +   D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 710   TCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQR 769
              C+ V+  G   + A L V             E   Y  +     K + +        + 
Sbjct: 25143 RCKVVNDYGEDSSYAELFV---------KGVREVYDYYCR-RTMKKIKRRTDTMRLLERP 25192

Query: 770   PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG---RPITASSRITSIFNFG 826
             P+F  PL +      G N  F   +T   +P   V WYK G   +P     + T   + G
Sbjct: 25193 PEFTLPLYN-KTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 25249

Query: 827   YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                L I  +  +D   YTV A NK GE    A + V
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 3/97 (3%)

Query: 2638  VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
             +  AP  T  ++S+ ++  GQ+      V+ +  P  +++W+ NGV L   +++  T   
Sbjct: 25873 LDHAPRITLRMRSH-RVPCGQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTS 25929

Query: 2698  GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             G++TL I     DDSG Y    TN  GEA   A++ +
Sbjct: 25930 GVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 7/117 (5%)

Query: 1289 QLLEDAARRTKQVREDITVMQAPQ--FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEW 1346
            +LLE+       V  DI+  +A +  F   + N   +EG  V   C++   G    ++ W
Sbjct: 1223 ELLEEDGEEKMAV--DISESEAVESGFDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAW 1278

Query: 1347 FCNGKPIKTGHRFRPAYEFD-YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            + +GK IK G R++  +  D   +L +  V PED G+YT  A+N  G A+ S  L V
Sbjct: 1279 YKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1335



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 7/86 (8%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF---GFAALDILTVYG 1911
            ++ EG    + C++  YP P  ++ WY +GK ++ G RY+   DF   G A+L I  V  
Sbjct: 1255 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLP 1310

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            ED G YT  A N  G A+ S +L V+
Sbjct: 1311 EDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 96/395 (24%), Positives = 167/395 (42%), Gaps = 34/395 (8%)

Query: 1424 LEDTSRYK-KTDIIDESVTIKPRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLK-VE 1479
            L+D   Y  K      S  +K   V   K+++N  V E Q   F  +L   T  N+K V+
Sbjct: 2637 LDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL---THPNVKGVQ 2693

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W KNG  +    ++         +L I +    D  +Y  R    +G    S RL    T
Sbjct: 2694 WIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFR----LGRLGASARLHVE-T 2748

Query: 1540 TDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599
              I++  ++   LE   V  + S  H T  V        I   S K+  + E +      
Sbjct: 2749 VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEI-KPSDKHRLVSERKVHKLML 2807

Query: 1600 RLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPED-SGTYTCRA--I 1655
            + I  SDA    E+      L+  ++ F ET +      +I   +PE  + ++ C     
Sbjct: 2808 QNISPSDAG---EYTAVVGQLECKAKLFVETLHITKTMKNIE--VPETKTASFECEVSHF 2862

Query: 1656 NALGEAVTSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV---ITQAP 1711
            N     + +G+ I  S+K  I ++ +    +      ED+++Y      D+V   +T  P
Sbjct: 2863 NVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTP 2922

Query: 1712 VF-TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            +  T  +KDI   E     FE   + V    +  +WL+NGV I+++++          +L
Sbjct: 2923 IMITSMLKDINAEEKDTITFE---VTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSL 2979

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            N++ V+  D+  YT  A    G+A +++TL+V+++
Sbjct: 2980 NIRNVHFGDAADYTFVA----GKATSTATLYVEAR 3010



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 42/175 (24%), Positives = 76/175 (43%), Gaps = 6/175 (3%)

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            + L DS +      + V    AP    ++  P +++ G  A + C I+  P  N+R +W+
Sbjct: 4315 EALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSAP--NVRFQWF 4371

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG--QAVSSIRLNVQSK 1939
              G+ +    +    +    ++L+IL     D GEYTCKA N  G     +++ + V   
Sbjct: 4372 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGG 4431

Query: 1940 ESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHP 1994
            E  +R    E   E  + +   S  ++  +++   VE  +  K +K   V E  P
Sbjct: 4432 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEK-VKKPAVPEPPP 4485



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 45/198 (22%), Positives = 82/198 (41%), Gaps = 5/198 (2%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRDVTEGKMT-RFDCRVTGRPYPEVTWFINDRQIRDDY 436
             ET E + I E    P+  +  + ++VT+  +T  ++          + + +  R I  + 
Sbjct: 10206 ETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10265

Query: 437   NHKILVNESGNHALMITNVTLSDSGVVTCVARN--KSGETAFQCRLNVIEKEQVVAPKFV 494
              HK+  +   +    +  +   D+      A N    G+ +F C   +  K+++  P   
Sbjct: 10266 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSF-CTKPITCKDELAPPTLH 10324

Query: 495   ERF-STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
               F   L +R GE   L  R  G P P+++W KD   ++ +    I T      L+  +A
Sbjct: 10325 LDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKA 10384

Query: 554   KASDAAWYQCTAQNVAGS 571
             K SD+  Y    +N  GS
Sbjct: 10385 KRSDSGKYCVVVENSTGS 10402



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQKPRNSK---LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             V PP+I+  P+      +  G   +    + G P P + W K  Q L N+ + EI +T  
Sbjct: 16041 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDF 16100

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
              T+L V++  + DSG+Y L A+N  G
Sbjct: 16101 ATSLSVKDAVRVDSGNYILKAKNVAG 16126



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 23/70 (32%), Positives = 40/70 (57%)

Query: 2938  KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
             ++ P  +++WY NG  L++ S+   T+  G +TL+++D +  DSG Y     N +GEA  
Sbjct: 25901 QSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASD 25960

Query: 2998  SSTVYCTSKD 3007
              +T+  T  D
Sbjct: 25961 YATLDVTGGD 25970



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 2/130 (1%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           Q   T E +  +E A  P FV+  Q   V +G   R   RVTG P P V ++ +  +I+ 
Sbjct: 88  QATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             + +I   E   ++L+I      DSG  +  A N  G       L V  +E+V A K  
Sbjct: 147 SLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTK 205

Query: 495 ERFSTLNVRE 504
              ST  + E
Sbjct: 206 TIVSTAQISE 215



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F++ LQ +  +++G     + ++T +  PT  V++Y+DG  I +S            S
Sbjct: 104 PNFVQRLQSM-TVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I     ED+G+Y+V A N +G A STA + V     V A
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPA 201



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L S+  +++G +   + RV  I  P   + ++ +G +I++   ++ + +    +
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
            L I   Y EDSGTY   ATN +G A +T  L V G   +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 4/114 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYRTSNDFG 1900
            +AP+   ++   T + +G  AH+  R+   PDP    EWY NG K+ +S   Y    +  
Sbjct: 2030 EAPKIFERIQSQT-VGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERSDRIYWYWPEDN 2086

Query: 1901 FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
               L I  V  EDS     KAIN  G+  S   L VQ+K+ I    + +  + K
Sbjct: 2087 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2140



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 41/115 (35%), Positives = 54/115 (46%), Gaps = 10/115 (8%)

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFS----TLNVREGEPVVLNARAVGTPTPRI 522
            A N+ GE+     LNV+ ++  V P    R S    T+ V+ GEPV + A   G P P+I
Sbjct: 8874 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 8933

Query: 523  TWQKDGVPI-IPNPELRIHTD----GGAST-LDIPRAKASDAAWYQCTAQNVAGS 571
             W K+   I  P   L+I  +      A T L IP+A   D   Y  TA N  GS
Sbjct: 8934 EWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS 8988



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 30/108 (27%), Positives = 54/108 (50%), Gaps = 3/108 (2%)

Query: 1028  RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT 1087
             +Y   +++   +   PR    ++ ++++  GQ+  F   V  QS  T  V+WY NG ++ 
Sbjct: 25862 KYEVLSQQPFTLDHAPRITLRMR-SHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQ 25918

Query: 1088  SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              +++I   +  G + L+I     +DSG Y  V  N  GEA   A++ V
Sbjct: 25919 ESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 2/125 (1%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +PP   Q+ ++  +++G+  + QV+++G P P V ++++G  + +S   +I    +  +L
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +      DSG Y++ A N  G   ++  L V+   E  V  ++++ I  T Q     + 
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG--EEEVPAKKTKTIVSTAQISESRQT 219

Query: 384 EISEK 388
            I +K
Sbjct: 220 RIEKK 224



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 5/134 (3%)

Query: 354   AVESPTESYVQDQRSQY--ITDTQQRE--TEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
             ++ S  ES+V+   S +  I++  Q E  T + ++   + + P+   +  D  + EGK+ 
Sbjct: 26790 SMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVL 26849

Query: 410   RFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHALMITNVTLSDSGVVTCVAR 468
                C  TG P PEVTW    R+I      +  + N      L+I +V   D G+ T    
Sbjct: 26850 TVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLG 26909

Query: 469   NKSGETAFQCRLNV 482
             N+ G  +    +++
Sbjct: 26910 NEFGSDSATVNIHI 26923



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L ++  +R+G     + R+T    P +K  +Y +G  +++   F+   +     
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            L I+  YPEDSG Y   A N+ G A +TA + VQG+  +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 56/259 (21%), Positives = 98/259 (37%), Gaps = 12/259 (4%)

Query: 2887 VEQAEEARLAKGRRPSVPDTEYP-KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKI 2945
            V    EA++ +  R   P  E P  P  ++       ++EG+ + LE  +     P   +
Sbjct: 872  VLHGREAKVTETARVPAP-VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT--V 928

Query: 2946 EWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS 3005
             WY     +E    F++T   G   L + + +  DSG +TC A N+ G   TS  +    
Sbjct: 929  TWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988

Query: 3006 KDNLIERT---QHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD-IS 3061
             +   + T        TE    +++ +  +      +     G P     + K +V  + 
Sbjct: 989  SEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLV 1048

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTTDSG 3119
            EG    +   +   G+    + W  +G  +   +R +  Y    G   L I  T   D+G
Sbjct: 1049 EGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1106

Query: 3120 TYSCRATNKWGQAEISVKL 3138
             Y+    NK G+   S  L
Sbjct: 1107 EYTIVVRNKHGETSASASL 1125



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 10/140 (7%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PV    +  LE +  G  A F C ++  + P++   WF  G++I    +          +
Sbjct: 4337 PVIKRKIEPLE-VALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKCSIRSSKYISS 4393

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV---AGHRNI--ILDTQHPNGLEKIRQL 2223
            L+IL T   D G Y CKA+N+ G    T TL V    G + +  +L  + P   E++  +
Sbjct: 4394 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEV--V 4451

Query: 2224 EAQGHSTRIEVEEPKISPPR 2243
                   R E EEPK+ P +
Sbjct: 4452 LKSVLRKRPEEEEPKVEPKK 4471



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 4/114 (3%)

Query: 4603  VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
             VSLP   +    + K    PP+I+ P +  I A G+ +     + GKP PT +W KG+  
Sbjct: 12384 VSLPREAEGVY-EAKEQLLPPKILMPEQITIKA-GKKLRIEAHVYGKPHPTCKWKKGEDE 12441

Query: 4663  IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  S +  + +      L I +   +D G Y   A NS+G  T   K+KV   D
Sbjct: 12442 VVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG--TDTQKIKVVVMD 12493



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 3/95 (3%)

Query: 3278  SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
             S E P    +++DVT  + G++A    ++V    PD+K  W+  GK+L    +Y+   D 
Sbjct: 24032 SGEAPGIRKEMKDVTTKL-GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDG 24088

Query: 3338  GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
                 L ++   +E+ G Y C+ATN++G   T + L
Sbjct: 24089 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 4/135 (2%)

Query: 1803  QSKASLQLESQHESALQKIQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLSEGQS 1861
             +  A   + S++ES    ++  + S R Y+        ++ APR   ++    ++  GQ+
Sbjct: 25835 ERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH-RVPCGQN 25893

Query: 1862  AHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
               +   ++    P   V+WY NG  LQ   +   +N  G   L+IL  + +DSG Y    
Sbjct: 25894 TRFILNVQS--KPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVC 25951

Query: 1922  INNLGQAVSSIRLNV 1936
              N  G+A     L+V
Sbjct: 25952 TNYKGEASDYATLDV 25966



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 2/107 (1%)

Query: 1696  KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
             KY+  S Q   +  AP  T+ M+  RV   Q   F   +     P   V+W  NGV ++ 
Sbjct: 25862 KYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQE 25919

Query: 1756  SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             S+++   +  G + L +   + +DSGTY     N  GEA   +TL V
Sbjct: 25920 SSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 36/147 (24%), Positives = 68/147 (46%), Gaps = 9/147 (6%)

Query: 3391  EGGLEKLQTLEDSMVR-RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
             EG L  +   ++ +V+ + D ++ +E   AP F +     +N+ EG+N  F   ++   +
Sbjct: 26607 EGILTCISKTKEGIVKCQYDLTLSKELSDAPAF-ISQPRSQNINEGQNVLFTCEIS--GE 26663

Query: 3450  PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
             P+ ++EW+ N   +   S            LEI      DSG+Y  +A N  G+   TAS
Sbjct: 26664 PSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATAS 26723

Query: 3510  MKV-----QGKRNIILESQLPKGMEGT 3531
             + V     +  R ++L +     ++G+
Sbjct: 26724 LMVLPLVEEPSREVVLRTSGDTSLQGS 26750



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 11/122 (9%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKT 2428
            +T Q P FTQPLQ++  + EG TA F+  +   G P  +V WFR+ ++I  S+   +  +
Sbjct: 1    MTTQAPTFTQPLQSV-VVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQIS 57

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ 2488
               G   +TI  V   + G Y  +A+N  G+              ++ ET  P  ++++Q
Sbjct: 58   FSDGRAKLTIPAVTKANSGRYSLKATNGSGQ------ATSTAELLVKAETAPPNFVQRLQ 111

Query: 2489 KL 2490
             +
Sbjct: 112  SM 113



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 5/98 (5%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDF 2697
            QAP FT  L+S   ++EG     EA +     P  ++ WF++G  ++T     ++ +F  
Sbjct: 4    QAPTFTQPLQSV-VVLEGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G   L+I ++   +SG Y+ KATN  G+A STA + ++
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/79 (32%), Positives = 40/79 (50%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G  A     +    KP IQW   G L+  + D++ + +G++  L+I  T  ED G +TC 
Sbjct: 3471 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 3530

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            A+   G+   SA L + SK
Sbjct: 3531 ASNDYGKTICSAYLKINSK 3549



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L + V +EGD +H   ++  +++    + W+F NK +PS  ++K   D +  +L I    
Sbjct: 4249 LVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVN 4304

Query: 2840 EED-SGIYTCKATNSKGSATTSGSL 2863
             ED  G Y C+A N  G   TS  L
Sbjct: 4305 TEDHQGEYVCEALNDSGKTATSAKL 4329



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 34/151 (22%), Positives = 66/151 (43%), Gaps = 4/151 (2%)

Query: 195   GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIST 254
             GY T    + Q       T++S   D  +     +  ++  FR +  +  VG S  + + 
Sbjct: 12335 GYITSYREEEQPA--DRWTEYSVVKDLSLVVTGLKEGKKYKFRVA-ARNAVGVSLPREAE 12391

Query: 255   EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
              +  +   + PPKI   P    ++ G   + +  + G P P   W K    ++ S+   +
Sbjct: 12392 GVYEAKEQLLPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12450

Query: 315   ITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 + + L +++  + DSG+Y+L AEN +G
Sbjct: 12451 HKADSSSILIIKDVTRKDSGYYSLTAENSSG 12481



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 25/81 (30%), Positives = 41/81 (50%)

Query: 498   STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
             S L V+ G  V L+A   G P P ++W+KDG  + P   +++       TL++      D
Sbjct: 12806 SLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKD 12865

Query: 558   AAWYQCTAQNVAGSTATRARL 578
             +  Y  TA+N +GS +   +L
Sbjct: 12866 SGDYTITAENSSGSKSATIKL 12886



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 46/142 (32%), Positives = 67/142 (47%), Gaps = 15/142 (10%)

Query: 4580  DSGKYE--CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP-LKDKI-VA 4635
             + GKYE    A N+AG     +E   ++   KD+ +       AP  +++P +KD + + 
Sbjct: 13843 EGGKYEFRIRAKNTAGAISAPSESTETI-ICKDEYE-------APTIVLDPTIKDGLTIK 13894

Query: 4636  EGQAIEFSC-KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694
              G  I  +   I+GKPLP   W K  K I+PS   Q++ T     L I  A  +D G+Y 
Sbjct: 13895 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 13954

Query: 4695  CVAYNSAGRVTVAAKLKVTQPD 4716
               A N  G  T    +KVT  D
Sbjct: 13955 ITATNPFG--TKVEHVKVTVLD 13974



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 25/89 (28%), Positives = 41/89 (46%)

Query: 490   APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
             AP   +    +  + GE   L+ + VG P P I W + G  +I + + ++ +DG   TL 
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094

Query: 550   IPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +   +  D   Y C A N  G   T ++L
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 2/94 (2%)

Query: 637   PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
             P FI   +S    EG  + F   I   G+P+ +IEW KN   I  SS  +        SL
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSL 26694

Query: 697   DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTP 730
             ++ + ++ DSG+YT +A +  G     A L V P
Sbjct: 26695 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLP 26728



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E +PP F Q  ++    QG   + + ++ G PTPVV + R  A +     + +    Q G
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQI---SQEG 156

Query: 128 DV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           D+ SLLI +  P D G Y+  A N  G A  +  +  +G
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L ++  ++G  +  +  V  +  PT  ++++ +   + S   ++ + +    SL I
Sbjct: 106  FVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               Y EDSG Y+  ATNS G AT++  L   G++ +    +  +       + ++ + R+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV--PAKKTKTIVSTAQISESRQTRI 221

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923
             K              E +I  AA  QL
Sbjct: 222  EKKIEAHFDARSIATVEMVIDGAAGQQL 249



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 14/128 (10%)

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866
            KI+E E G I +   + P++ TP      +     EE + V     +   ++    + WY
Sbjct: 4229 KIQEAEGGFIKE---DGPMIHTP------LVDTVSEEGDIVHLTTSITNAKE----VNWY 4275

Query: 3867 RNGKLLPSGHRYRTVYDMGFVSLDILYVYAED-SGEYICRAVNDFGEDFTKATISCKKLP 3925
               KL+PS  +++ + D    +L I  V  ED  GEY+C A+ND G+  T A ++  K  
Sbjct: 4276 FENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 4335

Query: 3926 DIILQNQV 3933
              +++ ++
Sbjct: 4336 APVIKRKI 4343



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/131 (23%), Positives = 60/131 (45%), Gaps = 2/131 (1%)

Query: 449   ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVREGEP 507
             +L++T +           ARN  G +  +    V E KEQ++ PK +     + ++ G+ 
Sbjct: 12360 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP-EQITIKAGKK 12418

Query: 508   VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
             + + A   G P P   W+K    ++ +  L +H    +S L I      D+ +Y  TA+N
Sbjct: 12419 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN 12478

Query: 568   VAGSTATRARL 578
              +G+   + ++
Sbjct: 12479 SSGTDTQKIKV 12489



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 25/94 (26%), Positives = 41/94 (43%)

Query: 4410  PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
             PP F        V   E  + +V F G P P + W+++N P+K +      +    S+L 
Sbjct: 15650 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15709

Query: 4470  IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
             I+    ED   +     N  G A  + N++V +K
Sbjct: 15710 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15743



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1976  EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
             E P   K +K+     G    L   +  V  P   ++WY  G+ + Q  ++K + D    
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH 24091

Query: 2036  ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
              L ++    ED G Y C ATN VGE  T+S + + A
Sbjct: 24092 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 35/144 (24%), Positives = 64/144 (44%), Gaps = 5/144 (3%)

Query: 1946  SQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIKNAEVTEGHPVHLEATLTPV 2004
             S++ES    ++  +   R    +    F ++  P+    +++  V  G        L   
Sbjct: 25844 SRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRF--ILNVQ 25901

Query: 2005  NDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
             + PT  V+WY NG  +Q+  +   T   G + L+IL  + +D+GTY    TN  GEA  +
Sbjct: 25902 SKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA--S 25959

Query: 2065  SSVKVDAKSGLYLDTLDEQRLKKI 2088
                 +D   G Y     ++R +++
Sbjct: 25960 DYATLDVTGGDYTTYASQRRDEEV 25983



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 5/114 (4%)

Query: 3674  KLEETLHKREEITIEDE--KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731
             K ++T  ++ E+  +      + PR T+ ++ +  VP G    F   V+    PT  + W
Sbjct: 25854 KTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH-RVPCGQNTRFILNVQ--SKPTAEVKW 25910

Query: 3732  FHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             +HNG      S++H  N  G + L+I   +  D+G Y    TN  G A+  A +
Sbjct: 25911 YHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATL 25964



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 1/118 (0%)

Query: 378  ETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            E +  ++ISE +A+   F    ++  + EG    F C+++G P P++ W+ + ++I+   
Sbjct: 1230 EEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE 1289

Query: 437  NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             +++   + G  +L I  V   D G+ T  A N  G      +L V     + AP ++
Sbjct: 1290 RYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1347



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 86/385 (22%), Positives = 153/385 (39%), Gaps = 39/385 (10%)

Query: 1558 LEDRSKYH------RTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKV 1611
            LED   Y+      RTD   +V   A    +  +N+EI EG++A F   +  +S  +  V
Sbjct: 6029 LEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEF---VCSISKESFPV 6085

Query: 1612 EWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA---VTSGIAI 1668
            +W  ++K L+SG ++    +     L +     +D GTY      A   A   V   + I
Sbjct: 6086 QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRI 6145

Query: 1669 VHSKKSIYLESQHEGALP-RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKD-IRVAENQ 1726
            V   K   ++ Q E      +N     +K+ R+   +E I  +  + +  KD +     +
Sbjct: 6146 VVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRN---EEAIFDSSKYIILQKDLVYTLRIR 6202

Query: 1727 AAHFEARL-IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPEDSGTYT 1784
             AH + +    V     R E +++     A+N +    D   V  L       + S T+ 
Sbjct: 6203 DAHLDDQANYNVSLTNHRGENVKS-----AANLIVEEEDLRIVEPLKDIETMEKKSVTFW 6257

Query: 1785 CRAINELGEAV----TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY-----QRRED 1835
            C+ +N L   +        +   ++ S +++        K     D   Y     Q +  
Sbjct: 6258 CK-VNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSV 6316

Query: 1836 VEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
             E+ + +AP  F+  L   T ++E   A + C++         V+WY NG+ ++ G +Y+
Sbjct: 6317 AELLIIEAPTEFVEHLEDQT-VTEFDDAVFSCQLSR---EKANVKWYRNGREIKEGKKYK 6372

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTC 1919
               D     L I     +D  EY C
Sbjct: 6373 FEKDGSIHRLIIKDCRLDDECEYAC 6397



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQKPRNSKL---QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             V PP++    +   +   + G   +    ++G P P ++W K+G  +    + EII+T N
Sbjct: 19287 VEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN 19346

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
             HT L V++  + D+G Y L  +N  G
Sbjct: 19347 HTLLTVKDCIRRDTGQYVLTLKNVAG 19372



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 32/118 (27%), Positives = 55/118 (46%), Gaps = 7/118 (5%)

Query: 1708  TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-FG 1766
             T  P+F   + +    E Q+  FE R+  +  P L+  W ++G P+     +  +H+   
Sbjct: 25295 TLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLD 25352

Query: 1767  YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ----SKASLQLESQHESALQK 1820
             Y AL+++   PED+G Y   A N  G     + L V+     K   + + +HE  +QK
Sbjct: 25353 YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQK 25410



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           +PP      KN    +G +   E  + G P+P V+W R+   +     + + +  Q+G  
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF--QSGIA 952

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            L+I++    D G +TC+A N+ G    S Y+
Sbjct: 953 RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL 984



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 8/116 (6%)

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
            + LE+    K    I ES  ++  F  R K+   ++EG  V F CK+        K+ W+
Sbjct: 1223 ELLEEDGEEKMAVDISESEAVESGFDLRIKNYR-ILEGMGVTFHCKMSGYPLP--KIAWY 1279

Query: 1482 KNGQPVTIGHRFRPIHDF---GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            K+G+ +  G R++   DF   G  +L I  ++ ED GIYT  A N+ G    S +L
Sbjct: 1280 KDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL 1333



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 12/173 (6%)

Query: 3050 FTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLE 3109
            FT   +D+V   +  +A +E     T +  + ++W+ +G  +    + R      +  L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 3110 ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHF 3169
            IL   T+D+  YSC         + +VK       +G    F   +Q+IE + +  S   
Sbjct: 2187 ILTIDTSDAEDYSCVLVE-----DENVKTTAKLIVEGAVVEFVKELQDIE-VPESYSGEL 2240

Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            EC V P    +++ +WYHN   ++ + +    S  G   L +      D GEY
Sbjct: 2241 ECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2290



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 42/196 (21%), Positives = 85/196 (43%), Gaps = 7/196 (3%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
             ET E ++ SE    P  + +    D+T+  ++    +       ++T ++ + Q +    
Sbjct: 14457 ETTEPVKASEAPSPPDSLNIM---DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 14513

Query: 438   HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER- 496
                +    G   + + N+T  +      +A N +G +A +    VI KEQ + P+   R 
Sbjct: 14514 WTHITTVKGLECV-VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRG 14572

Query: 497   -FSTLNV-REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
              +  L + + G+ + +    +G P P +TW+K    +     +   T   ++ L+I    
Sbjct: 14573 IYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECV 14632

Query: 555   ASDAAWYQCTAQNVAG 570
              SD+  Y  TA+N+ G
Sbjct: 14633 RSDSGPYPLTARNIVG 14648



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 23/83 (27%), Positives = 37/83 (44%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P +  P     +  G+ ++    ++G+P P + W K  + +K +    +  TA    L I
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVT 4705
              E   +D G Y   A NSAG  T
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTAT 17897



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 70/294 (23%), Positives = 120/294 (40%), Gaps = 28/294 (9%)

Query: 4218  YDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEY 4277
             Y +  Q QR   E E     R V   Q + +++ EL   + KE     ++S K+ + +  
Sbjct: 25690 YRQPKQRQRIMAEREDEELLRPVTTTQHLSEYKSELD-FMSKE-----EKSRKKSRRQRE 25743

Query: 4278  YNKLQELENEQVIKESRLRESTHQYA--IPGDKVTSNTVAKSMAQRYE------DNLDQT 4329
               ++ E+E E  I +   RES+   +  +   +  S T  + M    E         ++ 
Sbjct: 25744 VTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEY 25803

Query: 4330  EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAK-QKQTQKEVVGDKEITRKITSTETT 4388
             E+ TE+R       +PR P P  S     E  +++ ++  + ++    E  +    T+ T
Sbjct: 25804 EDDTERRSPTPERTRPRSPSPVSS-----ERSLSRFERSARFDIFSRYESMKAALKTQKT 25858

Query: 4389  EIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN 4448
               E K    E + + P      P  T +M+  RV   +  RF +    +P   +KWY   
Sbjct: 25859 S-ERK---YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG 25914

Query: 4449  FPIKNSPDFQIHTFSTKSILI--IRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
               ++ S   +IH  +T  +L   I     +DS  + AV  N  G A   A L V
Sbjct: 25915 VELQESS--KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 3/105 (2%)

Query: 2242  PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
             PR    +R +  V  G+   F   V+    P   +++YHNG  LQ +++ H T   G ++
Sbjct: 25877 PRITLRMR-SHRVPCGQNTRFILNVQS--KPTAEVKWYHNGVELQESSKIHYTNTSGVLT 25933

Query: 2302  LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQR 2346
             L+I  C  +D+G Y     N  G  +   ++ VT        SQR
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQR 25978



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)

Query: 2788  GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
             G N  F  NV+    PT +++W+ N   L   ++   T+    ++L+I   + +DSG Y 
Sbjct: 25891 GQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 25948

Query: 2848  CKATNSKGSATTSGSLRCTG 2867
                TN KG A+   +L  TG
Sbjct: 25949 AVCTNYKGEASDYATLDVTG 25968



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/74 (32%), Positives = 38/74 (51%)

Query: 3312  PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
             P  +V+W++NG +L    +    +  G++ L+IL C+ ++SG Y  V TN  G  S  A 
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYAT 25963

Query: 3372  LKCTSKENLILDSQ 3385
             L  T  +     SQ
Sbjct: 25964 LDVTGGDYTTYASQ 25977



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/93 (30%), Positives = 44/93 (47%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I +K    ++  G  A+F  ++   P  R  WFK G+ +  S+K  I ++   ++L +
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4396

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
              TQ  D G YT  A N  G +  +  L V  P
Sbjct: 4397 LRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 4623 PEI---IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            PEI   ++ L    V  G  IE    + GKP P + W K D ++K  K   +     + T
Sbjct: 7191 PEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 7250

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            + I ++   D G Y   A N  GR T   ++ V
Sbjct: 7251 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 25/69 (36%), Positives = 37/69 (53%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L+ G   + +  +SG P P + W K+G+ L  + K EI      T L  +++ + DSG Y
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAY 15035

Query: 337   TLLAENPNG 345
             TL A NP G
Sbjct: 15036 TLTATNPGG 15044



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 82/394 (20%), Positives = 149/394 (37%), Gaps = 41/394 (10%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             R  V   G P P +KW + +  I+++    + +  T   L++  V   DS  +    EN 
Sbjct: 16464 RLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTS--LVLDNVNRYDSGKYTLTLENS 16521

Query: 4489  GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
              GT      + V +          PP        VN+   ++ +    +T   P+    L
Sbjct: 16522 SGTKSAFVTVRVLDTPS-------PP--------VNLKVTEITKDSVSITWEPPL----L 16562

Query: 4549  KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV--VSLP 4606
               G K++  I  K      +Y  ++   + ++S K + +    +   R  AE    + LP
Sbjct: 16563 DGGSKIKNYIVEKREATRKSYAAVVTNCH-KNSWKIDQLQEGCSYYFRVTAENEYGIGLP 16621

Query: 4607  ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
             A    P    K A  P    +   D +     ++ ++          +Q+    +     
Sbjct: 16622 AQTADP---IKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE 16678

Query: 4667  KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-------VTVAAKLKVTQPDQAD 4719
             K+ + +R      + I+     +E  ++ VA N  GR       V + AK  V +PD   
Sbjct: 16679 KWSECARVKSLQAV-ITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK- 16736

Query: 4720  NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
               PA +      V  GQ  + +  I+ + KPTI W ++G  + +T    +    +   L 
Sbjct: 16737 --PAFSSYS---VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLS 16791

Query: 4780  IGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             I  T+++D G +        GQ   S ++V   K
Sbjct: 16792 IKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 16825



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 35/132 (26%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 452   ITNVTLSDSGVVTCVARNKSGETAFQCRLN--VIEKEQVVAP--KF-VERFSTLNVREGE 506
             +T ++  D      +ARN  G  +   + +  ++ +++ V P  +F  E F  L ++ GE
Sbjct: 21418 VTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGE 21477

Query: 507   PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
              + + A   G P PR+TW KDGV I     + I    G+++L +  A       Y   A+
Sbjct: 21478 SLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAK 21537

Query: 567   NVAGSTATRARL 578
             N +GS     ++
Sbjct: 21538 NASGSAKAEIKV 21549



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 6/131 (4%)

Query: 734  IERTSQHPETLQYI-QQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEA 792
            I++ +      +Y+ + L D  K      +       P   R ++ L E+  G  A F  
Sbjct: 4300 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPL-EVALGHLAKFTC 4358

Query: 793  QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKL 851
            ++   S P +R +W+K GR I  S +  SI +  Y+ SL I+  +  D G YT +A N+ 
Sbjct: 4359 EIQ--SAPNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4415

Query: 852  GEAISTASIRV 862
            G    TA++ V
Sbjct: 4416 GSVSCTATLTV 4426



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 74/400 (18%), Positives = 148/400 (37%), Gaps = 24/400 (6%)

Query: 4367 QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHE 4426
            + ++ VV DKE   ++ +     +   ++  E VV     P   P    +     V E E
Sbjct: 7848 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD--PDCKPTIDLETHDIIVIEGE 7905

Query: 4427 QARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAE 4486
            +    V F   P+P + W+++   +K S    +      + L + +    D+ ++    E
Sbjct: 7906 KLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLE 7965

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            N+ G+A  S N+ V         G+  P   + A ++  +S +L     +  G  PI ++
Sbjct: 7966 NKLGSATASINVKVI--------GLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPI-LH 8016

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            ++   ++        ++  +   +  + +  P     +   A+N  G         +  P
Sbjct: 8017 YVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGE---YIELKNP 8073

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
                 PK Q        E+  P  +   I  +    +   KI+G  +  +   KG++  K
Sbjct: 8074 VIAQDPK-QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIA--KGEERWK 8130

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
                  +      YT +  E   E +  ++  A N+AG    +     T+     + P +
Sbjct: 8131 RCNEHLVPILT--YTAKGLEEGKEYQ--FRVRAENAAGISEPSRATPPTKAVDPIDAPKV 8186

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGALIPE 4763
                 + V  G        I+    PTI W++ E  ++PE
Sbjct: 8187 ILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPE 8226



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 3/120 (2%)

Query: 4596  RCDAECVVSLPATKDKPKPQTKAANAPPEI---IEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
             R  AE +V L         + +    PP +   ++ ++  +V  G  + F   I G P+P
Sbjct: 10984 RVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVP 11043

Query: 4653  TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             T +W      IK  +++ +        L I      D G+Y+    N+AG  TVA  L V
Sbjct: 11044 TAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 8/144 (5%)

Query: 375   QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
             +++ T  +I+ +   LA + +   +   V EG+  RF C   G P P VTW    + +  
Sbjct: 26050 EEKSTTRKIKTT---LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLST 26106

Query: 435   DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
                H++   +       I++V  SD G  + V  N  G+   +  L  I+K +V      
Sbjct: 26107 SARHQVTTTKY-KSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL-TIQKARVTEKAVT 26164

Query: 495   ERFSTLNVREGEPVVLNARAVGTP 518
                S   V+  EP V +  AV +P
Sbjct: 26165 ---SPPRVKSPEPRVKSPEAVKSP 26185



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 44/177 (24%), Positives = 74/177 (41%), Gaps = 12/177 (6%)

Query: 3346 YCYEENSGEYE---CVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKL--- 3397
            + Y E   EYE    +   K+ +D+         +E  I   + +L + +E  + K    
Sbjct: 1163 FVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLE 1222

Query: 3398 QTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWY 3457
            + LE+    +    + E +     F + + N   L EG    F  +++    P  K+ WY
Sbjct: 1223 ELLEEDGEEKMAVDISESEAVESGFDLRIKNYRIL-EGMGVTFHCKMSGYPLP--KIAWY 1279

Query: 3458 WNGKSLKAGSRFR-TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             +GK +K G R++  F   G   L I    PED G Y   A N  G A+ +  + V+
Sbjct: 1280 KDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 69   PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
            P PP   Q  +      G  A+F   + G P P +SW +++  L    K    ++ Q  +
Sbjct: 3190 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQ--E 3247

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
             +LL+ +  P D   YTC A+N YG A  S  +  E
Sbjct: 3248 YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 49/174 (28%), Positives = 76/174 (43%), Gaps = 16/174 (9%)

Query: 1773 KY-VNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQ 1831
            KY ++PE+   +  ++  +  +A T  T  V S A +  E Q ES     ++ E SS   
Sbjct: 4164 KYLISPEEVSYFNVQSRVKYLDA-TPVTKGVAS-AVVSDEKQDESLKPSEEKEESSSESG 4221

Query: 1832 RREDVEVAVNQAPRFITQLNGP--------TKLSEGQSAHYECRIEPYPDPNMRVEWYFN 1883
              E   V + +A     + +GP        T   EG   H    I    + N    WYF 
Sbjct: 4222 TEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVN----WYFE 4277

Query: 1884 GKVLQSGHRYRTSNDFGFAALDILTVYGED-SGEYTCKAINNLGQAVSSIRLNV 1936
             K++ S  +++   D     L I  V  ED  GEY C+A+N+ G+  +S +L V
Sbjct: 4278 NKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 42/199 (21%), Positives = 83/199 (41%), Gaps = 13/199 (6%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            +  ++Y+ + + + T  ++ I  + +  +F+   +D    E +   F   ++      V 
Sbjct: 5407 EDEAKYMFEAEDKHTSGKLII--EGIRLKFLTPLKDVTAKEKESAVFTVELS-HDNIRVK 5463

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
            WF ND+++    +   + +E   H++   ++++ D+  +   A   S E     +L V+E
Sbjct: 5464 WFKNDQRLHTTRSVS-MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEA----KLTVLE 5518

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
             +    P F  +       E + V+L         P + W KDG  I P+    I  DG 
Sbjct: 5519 GD----PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGK 5573

Query: 545  ASTLDIPRAKASDAAWYQC 563
               L + +A  SD   Y C
Sbjct: 5574 KRMLILKKALKSDIGQYTC 5592



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 10/246 (4%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             + ++   G+PLP +   R+  P+K +  F     +    + +++    D+  +   A N 
Sbjct: 19998 KVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANS 20057

Query: 4489  GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
              GT K   N+VV +  R G     PP+  +   ++   S  L     K  G   +  Y L
Sbjct: 20058 SGTTKAFINIVVLD--RPG-----PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL 20110

Query: 4549  KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG-EARCDAECV-VSLP 4606
                ++    +  ++        + +++    +  ++   A N  G     D+ CV V LP
Sbjct: 20111 LK-RETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLP 20169

Query: 4607  ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
              T   P       N   E I     + V+ G +      +  K   ++ W K +KL+  +
Sbjct: 20170 YTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRT 20229

Query: 4667  KYFQMS 4672
              +F+++
Sbjct: 20230 THFKVT 20235



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 4/97 (4%)

Query: 2642  PIFTTHLKSYDKLV--EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
             PI     + +D L+   G+ + ++A V+ R  P  ++ WFK+GV +     ++ T   G 
Sbjct: 21459 PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVP--RVTWFKDGVEIEKRMNMEITDVLGS 21516

Query: 2700  VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              +L +     D  G+YT +A N  G A +   +K++D
Sbjct: 21517 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21553



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ GA  +  V +SG P P +TW K G  L  +++  I TT +++ L V    + D+G Y
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSKQGIDL--ASRAIIDTTESYSLLIVDKVNRYDAGKY 23018

Query: 337   TLLAENPNG 345
             T+ AEN +G
Sbjct: 23019 TIEAENQSG 23027



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 3830  PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
             P+   +++SH V   +  RF   V+ K  P   ++WY NG  L    +       G ++L
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTSGVLTL 25934

Query: 3890  DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             +IL  + +DSG Y     N  GE    AT+
Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEASDYATL 25964



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 2387  NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
             NI EGQ   F C +   G+P+ ++EWF+N   I  SS ++ +      S+ I +    D 
Sbjct: 26647 NINEGQNVLFTCEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 26704

Query: 2447  GVYMCRASNLLGE 2459
             G Y  +A N  G+
Sbjct: 26705 GKYTIKAKNFRGQ 26717



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F+ +++S TV +   VR + RV     P   +++YR+G  + S   ++   +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDL 158

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             SL I   Y EDSG Y   A N  G   + A +
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 32/89 (35%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH-DFSYVSLD 2834
            F   + N    EG  + F C +  S  P  KI W+ + K +  G RY+         SL 
Sbjct: 1247 FDLRIKNYRILEGMGVTFHCKM--SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLR 1304

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I     ED GIYT  A+N KG+A  SG L
Sbjct: 1305 IPVVLPEDEGIYTAFASNIKGNAICSGKL 1333



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 48/232 (20%), Positives = 83/232 (35%), Gaps = 8/232 (3%)

Query: 4583  KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             +Y   A N AG  +C   C          P  Q +  N   + +     K   +G A   
Sbjct: 19161 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKIT 19220

Query: 4643  SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                +  + LP  +W K +       YF+++   ++        F  +  D       S G
Sbjct: 19221 GYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEF-RVFARNAADSVSEPSESTG 19279

Query: 4703  RVTVAAKLKVTQPDQADNLPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALI 4761
              + V  K  V  P    ++      RD++V + G+  +    I  +  P I W ++G  I
Sbjct: 19280 PIIV--KDDVEPPRVMMDVK----FRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19333

Query: 4762  PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              E    ++I   N+ +L + +    DTG +       AG    +    V  K
Sbjct: 19334 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 35/146 (23%), Positives = 65/146 (44%), Gaps = 7/146 (4%)

Query: 4568  TYTLLILEAYPQDSG-KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
             T T  I+    Q+S  ++   A N+ G     +E V  +        P     + P E  
Sbjct: 20326 TETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGP---VIDLPLEYT 20382

Query: 4627  EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
             E +K +    G +++    I GKP PT++WYK DK ++ +    +  T D  ++ I +A 
Sbjct: 20383 EVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDAD 20439

Query: 4687  PEDEGDYKCVAYNSAGRVTVAAKLKV 4712
               + G Y+    N+ G  +   ++++
Sbjct: 20440 RLNSGCYELKLRNAMGSASATIRVQI 20465



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 23/69 (33%), Positives = 36/69 (52%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G   + +  + G P PRVTWFK+G  +      EI      T+L VR+  +   G Y
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21532

Query: 337   TLLAENPNG 345
             T+ A+N +G
Sbjct: 21533 TVEAKNASG 21541



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 6/106 (5%)

Query: 3544  TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLI--PVNDSSMRVEWFHNGKPLL 3601
             T  ++  +  SG  P       D+      +A   C+++  P+ D    ++W+  GK L+
Sbjct: 24022 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD----IKWYRFGKELI 24077

Query: 3602  TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
                + K  +D     L +    Q D G+YTC ATN  GE   S KL
Sbjct: 24078 QSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 12/139 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-- 2164
            Q P F   L S+  L EG  A FE  +     P   + WF +GQ I           F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSD 60

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
            G   L I      +SG Y  KATN  G+A +T  L V        +T  PN +++++ + 
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------ETAPPNFVQRLQSMT 114

Query: 2225 A-QGHSTRIEVEEPKISPP 2242
              QG   R++V    I  P
Sbjct: 115  VRQGSQVRLQVRVTGIPTP 133



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 4/130 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P F   ++ + V +      + R+   G P   V++ R+G  I++S       +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L +    PEDSGTY+  A N +G A +++ L VQ +   ++ ++    +    Q+ +S
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--EVPAKKTKTIVSTAQISES 216

Query: 1828 SRYQRREDVE 1837
             + +  + +E
Sbjct: 217  RQTRIEKKIE 226



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 4/134 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+  L+S+T  +G ++  + R+   G PT  +++ ++G  I++S  F         S
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
           L +     +DSG Y+  A ++ G A + A L V  +   E  ++  +T+    Q+ +  +
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV--QGEEEVPAKKTKTIVSTAQISESRQ 218

Query: 756 YQHQESIEEQTSQR 769
            + ++ IE     R
Sbjct: 219 TRIEKKIEAHFDAR 232



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYVAL 1770
            F + +K+ R+ E     F  ++   G P  ++ W ++G  I+   R  +  + D G  +L
Sbjct: 1247 FDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQD-GRASL 1303

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
             +  V PED G YT  A N  G A+ S  L+V+  A L
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPL 1341



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 20/136 (14%)

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LDITHTYEEDSGIYTCKAT 2851
            F C ++ +  P ++ +WF   + +    +  S     Y+S L+I  T   D G YTCKA+
Sbjct: 4356 FTCEIQSA--PNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKAS 4412

Query: 2852 NSKGSATTSGSLRCT---GDKNI--YFDTQHPQGKAGL-----------EAVEQAEEARL 2895
            N  GS + + +L  T   G+K +      + P+ K  +           E   + E  +L
Sbjct: 4413 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4472

Query: 2896 AKGRRPSVPDTEYPKP 2911
             K ++P+VP+   PKP
Sbjct: 4473 EKVKKPAVPEPPPPKP 4488



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            I+  P +F+  ++  TV E +   F C++  +   K  ++WYRNG+ +  G +Y+   D 
Sbjct: 6321 IIEAPTEFVEHLEDQTVTEFDDAVFSCQLSRE---KANVKWYRNGREIKEGKKYKFEKDG 6377

Query: 3885 GFVSLDILYVYAEDSGEYIC 3904
                L I     +D  EY C
Sbjct: 6378 SIHRLIIKDCRLDDECEYAC 6397



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/91 (27%), Positives = 43/91 (47%)

Query: 481  NVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH 540
            NV+ K+    P        + V EGE + +       P P ++W KDG  +  +  L + 
Sbjct: 7880 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 7939

Query: 541  TDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             D  ++ L++P++  +DA  Y  T +N  GS
Sbjct: 7940 NDHISAHLEVPKSVRADAGIYTITLENKLGS 7970



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)

Query: 4512  VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
             + PS  L     ++ +G+ ++++  V G    ++ W+K+G+ ++   R  + EE  T T+
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV-EETATSTV 17871

Query: 4572  L-ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
             L I E    D GKY   A NSAG A  +   +V
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 4/110 (3%)

Query: 467   ARNKSG-ETAFQCRLNVIEKEQVVAPKF-VERFS--TLNVREGEPVVLNARAVGTPTPRI 522
             A N++G     +  L V+ KEQ+  P+  ++ F   T+ VR G  + ++    G P P++
Sbjct: 19952 AENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 20011

Query: 523   TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             T  +DGVP+               T+++  +  +DA  Y+ TA N +G+T
Sbjct: 20012 TLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTT 20061



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS--RFTSIFRFGYI 694
           P F  PL+SV  +EG    FE  I   G P  ++ W ++GQ I  S+       F  G  
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + ++   +SG Y+ +A + +G A + A L V
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 2/117 (1%)

Query: 377   RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
             RE E   E  E+ L P+ + + +   +  GK  R +  V G+P+P   W   + ++    
Sbjct: 12388 REAEGVYEAKEQLLPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS- 12445

Query: 437   NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
             +H  +     +  L+I +VT  DSG  +  A N SG    + ++ V++      P F
Sbjct: 12446 SHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12502



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 2780  LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
             + ++  K G+     C +     P +K  W+   K L    +YK + D    +L +    
Sbjct: 24042 MKDVTTKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEE 24099

Query: 2840  EEDSGIYTCKATNSKGSATTSGSL 2863
             +ED G+YTC ATN  G   TS  L
Sbjct: 24100 QEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P+F+++  NA   +G +  FE ++ G P P + W +   PL       +  +E     +L
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEI-IHEGLDYYAL 25356

Query: 132   LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
              I+   P D G Y  TA N  G   C  ++Q E
Sbjct: 25357 HIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 22/61 (36%), Positives = 34/61 (55%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI WY   ++L  G + K   D    TL L++ +  D+ +YTC+A N  G A TS++
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279

Query: 3001 V 3001
            +
Sbjct: 3280 L 3280



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 7/136 (5%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P   + I+  EV  GH       +     P +R +W+  GR + +  +          +L
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSL 4394

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG--LYLDTLDEQRLKKIQE--LEK 2093
            +IL     D G Y CKA+N  G    T+++ V    G       L E++ +  +E  L+ 
Sbjct: 4395 EILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKS 4454

Query: 2094 YERPKPIEEEQPGQRP 2109
              R +P EEE+P   P
Sbjct: 4455 VLRKRP-EEEEPKVEP 4469



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+ ++  +    A G  AKF  +++  P     W +    + E +K S+R ++    + +
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4396

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            L  Q+   D GEYTC A N+YG   C+
Sbjct: 4397 LRTQVV--DCGEYTCKASNEYGSVSCT 4421



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 9/119 (7%)

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            G  A F C+++    PN+R +++  G+ +  + +  I       SL+I      D GEY+
Sbjct: 4351 GHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 4408

Query: 2317 VKAINALGHCTSAISMTVTAKGS-----IISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             KA N  G  +   ++TVT  G       +   ++PE  E++  L+S    KRPE  EP
Sbjct: 4409 CKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEV-VLKSVLR-KRPEEEEP 4465



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 4/128 (3%)

Query: 233   EVSFRESITKRYVGESDV-QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
             E SFR S  +   G SD  Q+S  +      V PP          +  G D +  V   G
Sbjct: 15619 EYSFRVS-AQNEKGISDPRQLSVPVIAK-DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG 15676

Query: 292   NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG-CIVTS 350
              P P VTW K+   L  + +    +T N++ L +++  + D GHY +   N  G  I T 
Sbjct: 15677 RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETL 15736

Query: 351   GYLAVESP 358
               + ++ P
Sbjct: 15737 NVIVLDKP 15744



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             GQ + +E  +  R  P   I W K+G+ L    R+  T    L TLSI     DD G Y 
Sbjct: 16747 GQDLKIEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYG 16804

Query: 2717  CKATNLLGEAVSTASIKI 2734
                 N++G+   TASI+I
Sbjct: 16805 ITVANVVGQ--KTASIEI 16820



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 19/63 (30%), Positives = 32/63 (50%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G +   ++   G P+P ++W K+G  L  S       T N  TL ++N +K   G YT++
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140

Query: 340   AEN 342
              +N
Sbjct: 21141 LDN 21143



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
             +  G+  R    V GRP P VTWF +  +I    N +I  +  G+ +L + + T    GV
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI-TDVLGSTSLFVRDATRDHRGV 21531

Query: 463   VTCVARNKSGETAFQCRLNVIEKE-QVVAP 491
              T  A+N SG    + ++ V +   +VV P
Sbjct: 21532 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21561



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ GA  +  +   G P P   W K    L  S + +I TT + +TL V N  ++D+G Y
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKY 21929

Query: 337   TLLAENPNG 345
             TL  EN +G
Sbjct: 21930 TLTVENNSG 21938



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             G+   L  Q+  R  P++K  W++ G  L    + K + D    TL++ +   +D G+YT
Sbjct: 24050 GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 2717  CKATNLLGEAVSTASIKIE 2735
             C ATN +GE  +++ + ++
Sbjct: 24108 CIATNEVGEVETSSKLLLQ 24126



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 3/81 (3%)

Query: 1057  EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD-FGYVALDIASVRAEDSGV 1115
             EGQS  FE RV      T+  +W  +G+ ++    I+  H+   Y AL I     ED+G 
Sbjct: 25311 EGQSVCFEIRVSGIPPPTL--KWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGY 25368

Query: 1116  YTVVARNAAGEAQLSASMTVE 1136
             Y V A N AG     A + VE
Sbjct: 25369 YRVTATNTAGSTSCQAHLQVE 25389



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 4/93 (4%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-DFGLVTL 2702
            F   +K+Y +++EG  V    ++     P  KI W+K+G  +  G R +  F   G  +L
Sbjct: 1247 FDLRIKNY-RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASL 1303

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             I  +  +D GIYT  A+N+ G A+ +  + +E
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 16/156 (10%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMS 1641
            +KN  I EG    F  ++   S   L K+ WY + K +K G R+  +    G  +L I  
Sbjct: 1251 IKNYRILEGMGVTFHCKM---SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1307

Query: 1642 CLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE-SQHEGALPRLNQLEDTSKYQRH 1700
             LPED G YT  A N  G A+ SG         +Y+E +   GA   +  LE  S+ +  
Sbjct: 1308 VLPEDEGIYTAFASNIKGNAICSG--------KLYVEPAAPLGAPTYIPTLEPVSRIR-- 1357

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
            S     ++++P+   P +      + A    AR+ P
Sbjct: 1358 SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSP 1393



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 43/165 (26%), Positives = 64/165 (38%), Gaps = 9/165 (5%)

Query: 3351 NSGEYECVATNKLGRDSTKANLKCTSKEN---LILDSQLPRGMEGGLEKLQTLEDSMVRR 3407
            N+ E      NKL     K   KC   +N   L++D       +G     + L DS    
Sbjct: 4268 NAKEVNWYFENKLVPSDEK--FKCLQDQNTYTLVIDKVNTEDHQGEYV-CEALNDSGKTA 4324

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
                +   K  APV    +  +E +  G  A F   +     PN++ +W+  G+ +    
Sbjct: 4325 TSAKLTVVKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESD 4381

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            +           LEI  T   D GEY C+A N YG    TA++ V
Sbjct: 4382 KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 1/102 (0%)

Query: 245   VGESDVQISTEIDRSLGPVSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             VG+      T+       ++PP +    R+   ++ G       + SG P+P+V+WFK+ 
Sbjct: 10300 VGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDE 10359

Query: 304   QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               ++  ++  I TT     L     ++SDSG Y ++ EN  G
Sbjct: 10360 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 24/75 (32%), Positives = 36/75 (48%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             ++ R E    G+P P  KW +    +  S    +H   + SILII+ V  +DS  ++  A
Sbjct: 12417 KKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTA 12476

Query: 4486  ENRGGTAKCSANLVV 4500
             EN  GT      +VV
Sbjct: 12477 ENSSGTDTQKIKVVV 12491



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 1/80 (1%)

Query: 500   LNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             L ++ G+ +VLNA ++ G P P+ +W K G  I P+   +I +   +S L I  A   DA
Sbjct: 13891 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDA 13950

Query: 559   AWYQCTAQNVAGSTATRARL 578
               Y  TA N  G+     ++
Sbjct: 13951 GEYTITATNPFGTKVEHVKV 13970



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 79/385 (20%), Positives = 146/385 (37%), Gaps = 32/385 (8%)

Query: 644   KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI 703
             K +    GG +     I+  G PT +++W K    I  ++       F  + LD  ++N 
Sbjct: 16453 KIINIRAGGSLRLFVPIK--GRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNR 16508

Query: 704   QDSGEYTCRAVSATGVAETKAVLHV----TPRATIERTSQHPETLQYIQQ---LEDYSKY 756
              DSG+YT    +++G       + V    +P   ++ T    +++    +   L+  SK 
Sbjct: 16509 YDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKI 16568

Query: 757   QHQESIEEQTSQRPQFIRPLQD-------LGELQEGRNAHFEAQLTP---VSDPTMRVEW 806
             ++   +E++ + R  +   + +       + +LQEG + +F         +  P    + 
Sbjct: 16569 KNY-IVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADP 16627

Query: 807   YKDGRPITASSRITSIFNFGYVSLNIMHLRAE-DAGS----YTVRAVNKLGEAISTASIR 861
              K         +IT + +    S+++   + E D GS    Y V    K  E  S  + R
Sbjct: 16628 IKVAEVPQPPGKIT-VDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA-R 16685

Query: 862   VAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISI 921
             V +   V  +L   E+  +                       +   +P+ K P     S+
Sbjct: 16686 VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK-PAFSSYSV 16744

Query: 922   KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
             + G     E  +   G     + W KDG P++ ++RI    +     L+IK     D G 
Sbjct: 16745 QVGQDLKIEVPIS--GRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQ 16802

Query: 982   YTCRAYNAIGQATTSANLTIVTKKD 1006
             Y     N +GQ T S  +  + K D
Sbjct: 16803 YGITVANVVGQKTASIEIVTLDKPD 16827



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 3830  PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
             P    ++K  T +  E  +  C++  +  P   I+WYR GK L    +Y+   D    +L
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD--IKWYRFGKELIQSRKYKMSSDGRTHTL 24093

Query: 3890  DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              ++    ED G Y C A N+ GE  T + +  +  P
Sbjct: 24094 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATP 24129



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 4407  PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP-IKNSPDFQIHTF-ST 4464
             P + P F ++++   V     A    +  G P P++KWYR+    I +   ++I  F   
Sbjct: 24427 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24486

Query: 4465  KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
                LII  V  +D+ V+   A N+GG+   +A+L VE
Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 3430 ENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPE 3488
            + + +G +AHF  R+    DP  + EWY NG  ++   R   +     V  L I     E
Sbjct: 2041 QTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2098

Query: 3489 DSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            DS   + +A N  GE  + A + VQ K+ I    +L   +    D +A  E
Sbjct: 2099 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFE 2149



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/63 (34%), Positives = 34/63 (53%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   V W+KDG+ + AS R+T   +     L +      DAG YT+   NKLG A ++ +
Sbjct: 7917 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 7976

Query: 860  IRV 862
            ++V
Sbjct: 7977 VKV 7979



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 4622  PPEIIEPL--KDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             PPE+   +  +D I V  GQ I    ++ G+P P + W K  K++   K   + +     
Sbjct: 11408 PPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV 11467

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNL 4721
              L+I EA   D G Y   A NS+G    +A + V  +P    NL
Sbjct: 11468 ELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNL 11511



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 21/68 (30%), Positives = 38/68 (55%)

Query: 278   QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337
             +E ++ + ++ + G P P V+W K    L    +  + ++  +TTL V + QKSD+G YT
Sbjct: 13498 KENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYT 13557

Query: 338   LLAENPNG 345
             +  +N  G
Sbjct: 13558 ITLKNVAG 13565



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 6/88 (6%)

Query: 71    PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYN-EQTGDV 129
             PP F+ +F       G + K +    G PTP V+W +   PL    K + R N E T + 
Sbjct: 15650 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL----KQTTRVNAESTENN 15705

Query: 130   SLL-IKQIGPGDEGEYTCTARNQYGEAI 156
             SLL IK     D G Y     N  GEAI
Sbjct: 15706 SLLTIKDACREDVGHYVVKLTNSAGEAI 15733



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 5/103 (4%)

Query: 1302  REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP-IKTGHRFR 1360
             + D+ + QAP F   L N+     +N  L C++   G     V+W+  GK  I  G ++R
Sbjct: 24423 KSDVPI-QAPHFKEELRNLNVRYQSNATLVCKV--TGHPKPIVKWYRQGKEIIADGLKYR 24479

Query: 1361  -PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                ++  Y  L + SV  +D+ VY  +ATNQ G    + +L V
Sbjct: 24480 IQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/93 (34%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 488   VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHT-DGGA 545
             + AP F E    LNVR      L  +  G P P + W + G  II +  + RI    GG 
Sbjct: 24428 IQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGY 24487

Query: 546   STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               L I      DA  YQ  A N  GS +  A L
Sbjct: 24488 HQLIIASVTDDDATVYQVRATNQGGSVSGTASL 24520



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 3149  PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
             PR T  +++   +  GQ+  F   V     P  +++WYHNG  ++ S++I   +  G + 
Sbjct: 25877 PRITLRMRS-HRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 25933

Query: 3209  LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
             L+I      DSG Y     N  GE    AT++  G
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 25968



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHD 1097
            TQ P F  PL+    ++EG +A FEA +         V W+ +G+ I+++    +Q    
Sbjct: 3    TQAPTFTQPLQSV-VVLEGSTATFEAHISGFP--VPEVSWFRDGQVISTSTLPGVQISFS 59

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             G   L I +V   +SG Y++ A N +G+A  +A + V+  ++
Sbjct: 60   DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 11/139 (7%)

Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            +IE+  P +  P+    ++  T V +G  AHF  +V  V  P+   E+Y NG  ++ + R
Sbjct: 2022 KIELS-PSMEAPKIFERIQSQT-VGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDR 2077

Query: 2291 FHITFDFGYV-SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG 2349
             +  +    V  L I+    ED+    VKAIN  G  +S   + V AK  I    +  + 
Sbjct: 2078 IYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDV 2137

Query: 2350 LEKIR------ELESAEPF 2362
            + K +      E E++EPF
Sbjct: 2138 VAKEKDTMATFECETSEPF 2156



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            V   KI +KP++    E A   F+V +S +  P V WF     +  S+KH +++      
Sbjct: 2746 VETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHK 2804

Query: 323  LRVRNTQKSDSGHYT 337
            L ++N   SD+G YT
Sbjct: 2805 LMLQNISPSDAGEYT 2819



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 34/145 (23%), Positives = 62/145 (42%), Gaps = 6/145 (4%)

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIK 1985
            + V+S  ++ + ++  ++ S+ +         E+ +  K    +  F+ E  P    P+ 
Sbjct: 4191 KGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLV 4250

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            +    EG  VHL  ++T   +    V WY   + V    +FK   D     L I     E
Sbjct: 4251 DTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE 4306

Query: 2046 D-TGTYMCKATNAVGEAVTTSSVKV 2069
            D  G Y+C+A N  G+  T++ + V
Sbjct: 4307 DHQGEYVCEALNDSGKTATSAKLTV 4331



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 2/125 (1%)

Query: 1278 DTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPV 1337
            +T++ Q     + L D+ +     +  +    AP   R +  +E   G      C +Q  
Sbjct: 4304 NTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA 4363

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             +  +R +WF  G+ I    +          +L++L     D G YTC+A+N+ G    +
Sbjct: 4364 PN--VRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT 4421

Query: 1398 CALRV 1402
              L V
Sbjct: 4422 ATLTV 4426



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/130 (30%), Positives = 58/130 (44%), Gaps = 9/130 (6%)

Query: 4583  KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             K+  +A+N+AGE+  D   V      KD+ +P     +A        +++ +  G  +  
Sbjct: 10689 KFRVLAVNAAGES--DPAHVPEPVLVKDRLEPPELILDA-----NMAREQHIKVGDTLRL 10741

Query: 4643  SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
             S  I G P P V W K D+   P+K  ++  T     L I  A  ED G Y     N AG
Sbjct: 10742 SAIIKGVPFPKVTWKKEDR-DAPTK-ARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAG 10799

Query: 4703  RVTVAAKLKV 4712
               TV+ K+ V
Sbjct: 10800 SKTVSVKVLV 10809



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 4495  SANLVVEEKRRQGRGGIV------PPSFTL--TAQNV-NVTSGQLVRLDTKVTGTKPIDV 4545
             +AN+V E + R+    ++      PP   L  T ++V  V  GQ +R+  +V G    D+
Sbjct: 11384 AANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDI 11443

Query: 4546  YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
              W K GK +  + R  ++++     L I EA   D GKY   A NS+G A+  A
Sbjct: 11444 TWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSA 11497



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 22/63 (34%), Positives = 32/63 (50%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G + + ++ + G P+P VTW K  Q L  + +    TT   T L +    +SDSG Y L 
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642

Query: 340   AEN 342
             A N
Sbjct: 14643 ARN 14645



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P++        V  GQ ++    I G+P PT+ W K    +K +    ++ + D  TL I
Sbjct: 16733 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16792

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVTVAAKL-KVTQPD 4716
              E   +D G Y     N  G+ T + ++  + +PD
Sbjct: 16793 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD 16827



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 50/213 (23%), Positives = 83/213 (38%), Gaps = 10/213 (4%)

Query: 797   VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAE-DAGS----YTVRAVNKL 851
             V  P   V+  K   P +   ++T + +    S ++M  + E D GS    Y V    K 
Sbjct: 17700 VGVPVETVDAVKAAEPPSPPGKVT-LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKG 17758

Query: 852   GEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEF 911
              E  S  +      + VT  L   ++ ++  K                    + T +P  
Sbjct: 17759 TEKWSIVAESKVCNAVVTG-LSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSL 17817

Query: 912   KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTI 971
             K P  +  SI+ G     E  +  IG     + W+KDG P++ ++R+          L I
Sbjct: 17818 KLPF-NTYSIQAGEDLKIE--IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874

Query: 972   KSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
             K     D G YT  A N+ G AT + ++ ++ K
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 482   VIEKEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
             +I K+ V  P+    V+    + V+ GE + +NA   G P P I+W KDG+ I       
Sbjct: 19281 IIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTE 19340

Query: 539   IHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             I +    + L +      D   Y  T +NVAG+
Sbjct: 19341 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGT 19373



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 785   GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
             G+N  F   L   S PT  V+WY +G  +  SS+I      G ++L I+    +D+G+Y 
Sbjct: 25891 GQNTRFI--LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 25948

Query: 845   VRAVNKLGEAISTASIRVAARSTVT 869
                 N  GEA   A++ V      T
Sbjct: 25949 AVCTNYKGEASDYATLDVTGGDYTT 25973



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/61 (37%), Positives = 31/61 (50%)

Query: 3591  VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             V+W+HNG  L   S++   N  G + LEI   +  D+G Y    TN  GEA+    L V 
Sbjct: 25908 VKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 25967

Query: 3651  G 3651
             G
Sbjct: 25968 G 25968



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 20/51 (39%), Positives = 30/51 (58%)

Query: 3082  IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
             ++W++NG  ++ S +I      G++ LEIL   T DSGTY    TN  G+A
Sbjct: 25908 VKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA 25958



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/108 (22%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +++ +  T  P     L+++ +++G +   + R+  +   T  V++Y +   ++S   F 
Sbjct: 94   ELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQ 151

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             +      +L I    PEDSGTY+  A N++G A ++   +V  ++ +
Sbjct: 152  ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 8/127 (6%)

Query: 619  ERARPYIPPGEEDRVYPPPQFIVP-----LKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            E  +  IP  + D++   P    P     ++S T  +G   HF  R+  VG P  + EW 
Sbjct: 2009 EEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRV--VGKPDPECEWY 2066

Query: 674  KNGQSIEASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            KNG  IE S R    +       L +  +  +DS     +A++  G   + A L V  + 
Sbjct: 2067 KNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126

Query: 733  TIERTSQ 739
             I  T +
Sbjct: 2127 LITFTQE 2133



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/130 (22%), Positives = 57/130 (43%), Gaps = 4/130 (3%)

Query: 3793 IVLESQLPQGMSGEKIKEL--ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850
            +V++    +   GE + E   + G+ + + K   +    P    +I+   V      +F 
Sbjct: 4298 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFT 4357

Query: 3851 CRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910
            C ++    P +R +W++ G+ +    +          SL+IL     D GEY C+A N++
Sbjct: 4358 CEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4415

Query: 3911 GEDFTKATIS 3920
            G     AT++
Sbjct: 4416 GSVSCTATLT 4425



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 47/203 (23%), Positives = 85/203 (41%), Gaps = 17/203 (8%)

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            + +  G  PI  Y ++  +  +PD          T + L+         ++   A+N  G
Sbjct: 8820 EPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIG 8879

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLP 4652
            E+  +    +++    D+  P  K        +    D I V  G+ +     + G P+P
Sbjct: 8880 ES--EPSLPLNVVIQDDEVPPTIKLR------LSVRGDTIKVKAGEPVHIPADVTGLPMP 8931

Query: 4653 TVQWYKGDKLI-KPSKYFQ-----MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             ++W K + +I KP+   Q     +SR+  +  L I +A  ED+G Y   A N  G V  
Sbjct: 8932 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 8991

Query: 4707 AAKLKV-TQPDQADNLPALTPLR 4728
               ++V  +P    NL A+T ++
Sbjct: 8992 NVHVEVYDRPSPPRNL-AVTDIK 9013



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/130 (25%), Positives = 63/130 (48%), Gaps = 7/130 (5%)

Query: 4677  EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK--VTQPDQADNLPALT---PLRD-I 4730
             E    +S    +   +++ +A N+AG ++  +     +T  D+ + LP ++     RD I
Sbjct: 17080 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVE-LPRISMDPKFRDTI 17138

Query: 4731  VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             VV  G+  + +  +  K  PTI+WLR    I E+   ++ +    A+L++ +    D G 
Sbjct: 17139 VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 17198

Query: 4791  FTCRATTAAG 4800
             +  RA+  AG
Sbjct: 17199 YILRASNVAG 17208



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 21/78 (26%), Positives = 39/78 (50%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  + E+   G P P I W ++  P+K +    +   +T ++L I++   +D   +   A
Sbjct: 17830 EDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTA 17889

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N  GTA  + +++V EK
Sbjct: 17890 TNSAGTATENLSVIVLEK 17907



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G+D      + G P P++ W K  + L    K  +  T    T  ++   +SDSG Y
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKY 22621

Query: 337   TLLAENPNGCIVTSGYLAV-ESP 358
             TL  +N +G    S  + V +SP
Sbjct: 22622 TLTVKNASGTKAVSVMVKVLDSP 22644



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +++G   +  + + G P P   W K GQ +  S +  I T+  HT L ++   + DSG Y
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTY 23708

Query: 337   TLLAENPNG 345
              L+ EN  G
Sbjct: 23709 DLVLENKCG 23717



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P   +  K+     G  A+   ++ G P P + W R    L++  KY M  + +T  +++
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095

Query: 132   LIKQIGPGDEGEYTCTARNQYGE 154
             + ++    DEG YTC A N+ GE
Sbjct: 24096 MTEE--QEDEGVYTCIATNEVGE 24116



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 2/69 (2%)

Query: 2391  GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
             G+ A   C++  VG P   ++W+R  K +  S +   + D    ++T+     EDEGVY 
Sbjct: 24050 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 2451  CRASNLLGE 2459
             C A+N +GE
Sbjct: 24108 CIATNEVGE 24116



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 3/68 (4%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH-EIITTHNHTTLRVRN-TQKSDSGHYT 337
             G     ++  SG P P +TW K GQ LI++N H ++I T + T+L   N  ++ D+G Y 
Sbjct: 24545 GEVVSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYV 24603

Query: 338   LLAENPNG 345
             + A+N  G
Sbjct: 24604 VCAKNRFG 24611



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGY 2299
            P F   L+    V EG TA FE  +     P   + ++ +G+ + ++      I+F  G 
Sbjct: 6    PTFTQPLQSVV-VLEGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L I      ++G YS+KA N  G  TS   + V A+ +  +  QR + +   +  +  
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 2360 EPFKRPEIPEPVTR 2373
               +   IP PV +
Sbjct: 123  LQVRVTGIPTPVVK 136



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 1/115 (0%)

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            ++++   P  V     + V EGE      R  G P P++ W  +G  I  +   R+  DG
Sbjct: 1788 DQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRP 598
                LDI   K+ D    + TA+N  G    + +L            +R   PRP
Sbjct: 1848 -IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRP 1901



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 18/168 (10%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            KD+  +    +A +E S+      ++ ++WF+    I+ S + R V    +  L +    
Sbjct: 2756 KDVTALENATVA-FEVSV---SHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 2811

Query: 3115 TTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174
             +D+G Y+       GQ      LEC  K   +    T  ++NIE + + ++A FEC V 
Sbjct: 2812 PSDAGEYTAVV----GQ------LECKAKLFVETLHITKTMKNIE-VPETKTASFECEVS 2860

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
              + P M   W  NG  +  S + K V       L I  T   DS EY
Sbjct: 2861 HFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEY 2905



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 65/284 (22%), Positives = 106/284 (37%), Gaps = 41/284 (14%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
            G+ A F+  +S +     TW K+G  +  S KH  I       L + + Q SD+G YT  
Sbjct: 4636 GSSAIFECLVSPSTAI-TTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT-- 4692

Query: 340  AENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ 399
                  C++  G     S  +  V++   +++     +  EE + + +        ++ +
Sbjct: 4693 ------CVLRLGNKEKTSTAKLVVEELPVRFV-----KTLEEEVTVVKGQPLYLSCELNK 4741

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +RDV   K  +      GR  P V   +                     AL I +   +D
Sbjct: 4742 ERDVVWRKDGKIVVEKPGRIVPGVIGLMR--------------------ALTINDADDTD 4781

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519
            +G  T    N +      C + V+E   V+    V+     +V+     +  A  +   T
Sbjct: 4782 AGTYTVTVENANNLECSSC-VKVVE---VIRDWLVKPIRDQHVKPKGTAIF-ACDIAKDT 4836

Query: 520  PRITWQK--DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            P I W K  D +P  PN +  I  DG    L I  A   D A Y
Sbjct: 4837 PNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY 4880



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 3/97 (3%)

Query: 485   KEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             +E++V P     V+    L V+ G  V   A   G P P   W  DG  I  +    + T
Sbjct: 11005 QEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVET 11064

Query: 542   DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             D  +S L I      D   YQ T  N AGS      L
Sbjct: 11065 DNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHL 11101



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 2648  LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             +KS   +  G +V L+A V  +  P   + W K+G  L     +K      L TL + S+
Sbjct: 12804 MKSLLTVKAGTNVCLDATVFGKPMPT--VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSV 12861

Query: 2708  RNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
                DSG YT  A N  G   +T  +K+ D+
Sbjct: 12862 NRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/69 (31%), Positives = 34/69 (49%)

Query: 936   IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             IG  T  V W KD  P++ ++R+          LTIK     D GHY  +  N+ G+A  
Sbjct: 15675 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 15734

Query: 996   SANLTIVTK 1004
             + N+ ++ K
Sbjct: 15735 TLNVIVLDK 15743



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 1707  ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
             +T  P   +P     +   +    E  +I  G P+  + W+++G P++ + R+       
Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVI--GRPRPNISWVKDGEPLKQTTRVNVEETAT 17868

Query: 1767  YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                L++K  N +D G YT  A N  G A  + ++ V  K
Sbjct: 17869 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/84 (29%), Positives = 38/84 (45%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P +  P     V   + ++      G+P  TV W K  + +K +    +S +    +L I
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 18957

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVTV 4706
              EA  ED G Y+    NSAG +TV
Sbjct: 18958 KEASKEDVGTYELCVSNSAGSITV 18981



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 21/70 (30%), Positives = 34/70 (48%)

Query: 4637  GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
             G  +       GKP P++ W K    +K S++ + S+T ++ TL I  A  E  G Y  +
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140

Query: 4697  AYNSAGRVTV 4706
               N+  R+ V
Sbjct: 21141 LDNAVCRIAV 21150



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 3/89 (3%)

Query: 3144  SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             + G+ P     ++++   K G++A   C +V    PD+K  WY  G+ +  S + K  SD
Sbjct: 24031 TSGEAPGIRKEMKDVT-TKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSD 24087

Query: 3204  FGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                  L +   +  D G Y C A N+ GE
Sbjct: 24088 GRTHTLTVMTEEQEDEGVYTCIATNEVGE 24116



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 2/80 (2%)

Query: 3435  GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
             G+N  F   L     P  +V+WY NG  L+  S+       G + LEI   + +DSG Y 
Sbjct: 25891 GQNTRFI--LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 25948

Query: 3495  CRAYNNYGEAVTTASMKVQG 3514
                 N  GEA   A++ V G
Sbjct: 25949 AVCTNYKGEASDYATLDVTG 25968



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDF--G 3613
            P FT     +++ E S+A FE  +   PV +    V WF +G+ + T +       F  G
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQISFSDG 61

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
               L I  V + ++G Y+ KATN  G+AT + +L VK
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVS 130
            P+F +  KN    +G   + + +  GNP P + W  K + ++  +KY  +R     G+ +
Sbjct: 1510 PMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWL-KNSDIIVPHKYPKIRIEGTKGEAA 1568

Query: 131  LLIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPE 164
            L I      D   YT TA N+ G     C V ++ E
Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 80/392 (20%), Positives = 151/392 (38%), Gaps = 29/392 (7%)

Query: 910  EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
            EF  P++DQ +++EG  A  E     +     +V+W K+G  +  S +     +     L
Sbjct: 5789 EFTKPLEDQ-TVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKL 5844

Query: 970  TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRY 1029
             I   T  D   YTC A +      TS NL +V       E   P    +++  E A   
Sbjct: 5845 VIHDCTPEDIKTYTCDAKD----FKTSCNLNVVPPH---VEFLRPLTDLQVREKEMARFE 5897

Query: 1030 SKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSA 1089
             + + E  K+          KG    +  + A     V  +  L    E+    +   ++
Sbjct: 5898 CELSRENAKVKWFKDGAEIKKGKKYDIISKGA-VRILVINKCLLDDEAEYSCEVRTARTS 5956

Query: 1090 NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL----SASMTVET-RSSIDTS 1144
              +    +      ++A++   ++    +V   +   A++         +ET R  I T 
Sbjct: 5957 GMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTE 6016

Query: 1145 SIHRGLYEKTRHIEESKFVE---PMYQIEEISKSKPVFVQPLSNPP--PVSEGKNIHLEC 1199
               R L  +  H+E++       P  + +   K   +  + +S P    + EG+     C
Sbjct: 6017 GRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVC 6076

Query: 1200 RLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLG 1259
             +     P   V+W  + +++  G ++    D     L +  AT  D G Y V     +G
Sbjct: 6077 SISKESFP---VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VG 6129

Query: 1260 SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL 1291
            +A  +A + VIE+  IV   ++ +  EQ +++
Sbjct: 6130 AARAAAHLTVIEKLRIVVPLKDTRVKEQQEVV 6161



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 6/120 (5%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
             E  + IE+ ++ ++P        RD   V  G + R    V+G+P P VTW +N+R +  
Sbjct: 10011 EVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQ 10070

Query: 435   DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             +   +     S   +++I N   S  GV + +A+N++GE      ++V++    V   F+
Sbjct: 10071 EATIETTAISS---SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 10127



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 24/69 (34%), Positives = 33/69 (47%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L+ G   +  V + G P P++TW K    L +    +I +T   T LR  N  K D+G Y
Sbjct: 13208 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13267

Query: 337   TLLAENPNG 345
              L  EN  G
Sbjct: 13268 ILTLENSCG 13276



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 35/113 (30%), Positives = 51/113 (45%), Gaps = 5/113 (4%)

Query: 235   SFRES-ITKRYVGESDVQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGN 292
             +FR S I    VGE  V    EI +R + P      A+  R   ++ G   +  V + G 
Sbjct: 14248 NFRISAINDAGVGEPAVIPDVEIVEREMAPDFELD-AELRRTLVVRAGLSIRIFVPIKGR 14306

Query: 293   PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             P P VTW K+   L   N+  I  T + T L +    + D+G + +  ENP G
Sbjct: 14307 PAPEVTWTKDNINL--KNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 14357



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/66 (33%), Positives = 32/66 (48%)

Query: 797   VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
             +  PT  V W+KD  P+  ++R+ +        L I     ED G Y V+  N  GEAI 
Sbjct: 15675 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 15734

Query: 857   TASIRV 862
             T ++ V
Sbjct: 15735 TLNVIV 15740



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 21/66 (31%), Positives = 33/66 (50%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G D Q  +   G P P VTW K+ + L +  ++ I  T + + L +    ++D+G Y L 
Sbjct: 20789 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 20848

Query: 340   AENPNG 345
              EN  G
Sbjct: 20849 IENGVG 20854



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 2122  KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
             K G+ A   C++  +  P   I W+  G+++    +Y+ + D     L ++    ED G 
Sbjct: 24048 KLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 24105

Query: 2182  YMCKATNKLGEAVNTCTL 2199
             Y C ATN++GE   +  L
Sbjct: 24106 YTCIATNEVGEVETSSKL 24123



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/80 (27%), Positives = 36/80 (45%)

Query: 266   PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
             P+I  + R+ ++  G + +F + +   P   V W+ NG  L  S+K     T    TL +
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936

Query: 326   RNTQKSDSGHYTLLAENPNG 345
              +    DSG Y  +  N  G
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKG 25956



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-- 3475
            +AP FT PL ++  L EG  A FEA ++    P  +V W+ +G+ +   +       F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            G   L I      +SG Y  +A N  G+A +TA + V+ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GF 3752
            P FT  ++ ++ V EG    F+  +   G P   + WF +G+  +T +       F  G 
Sbjct: 6    PTFTQPLQ-SVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L I  +   ++G Y+ +ATN  G AT+TA++   A+
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 3/153 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T E +V+   A  PP FV    ++TV +G   R   RVTG P P V +  +G  I +   
Sbjct: 92   TAELLVKAETA--PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 4157 YKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
            ++++ +G +Y   I +    D+G   V              L V    +      K    
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVID 4248
                  ++  R E ++E  F+ R +   + VID
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVID 242



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F+ ++Q +T + +G     + R+  +  P +K  ++ +G ++     ++   +  + 
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLY 159

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             L I   Y E+SG Y   ATN +GR ++ A L    +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            L D+ K    +    V   APV    ++ + VA    A F   +     P +R +W + G
Sbjct: 4317 LNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAG 4374

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
              I  S++ +        +L +      D G YTC+A NE G    ++TL V
Sbjct: 4375 REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             V  G+ I +  R++  G P   + W   G+ +    R     D   V L I  A  AD G
Sbjct: 11423 VRVGQTIRILARVK--GRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480

Query: 1249  EYTVRAVNHLGSAHTSAIVRVIER 1272
             +Y + A N  G A  SAIV V++R
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVLDR 11504



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 6/101 (5%)

Query: 2640  QAPIFTTHLKSYDKLV--EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-D 2696
             +AP     +K  D ++   G+   LEA V  R  P +  EW K+G  L   A+L+    D
Sbjct: 14960 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTM--EWSKDGKELEGTAKLEIKIAD 15017

Query: 2697  FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             F    ++ +S R D SG YT  ATN  G A    ++K+ DR
Sbjct: 15018 FSTNLVNKDSTRRD-SGAYTLTATNPGGFAKHIFNVKVLDR 15057



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 6/91 (6%)

Query: 1576  QAPICTTSLKNVEIKEGQRAHFERRLI--PVSDATLKVEWYHNNKPLKSGSRFTETNNFG 1633
             +AP     +K+V  K G+ A    +++  P+ D    ++WY   K L    ++  +++  
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD----IKWYRFGKELIQSRKYKMSSDGR 24089

Query: 1634  FVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                L +M+   ED G YTC A N +GE  TS
Sbjct: 24090 THTLTVMTEEQEDEGVYTCIATNEVGEVETS 24120



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 4/122 (3%)

Query: 246   GESD-VQISTEID-RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             GES+  +IS  I  +S  P+  P   ++ RN  ++  ++A    +++G+P+P V W++ G
Sbjct: 24409 GESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQG 24468

Query: 304   QRLI-NSNKHEIIT-THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTES 361
             + +I +  K+ I      +  L + +    D+  Y + A N  G +  +  L VE P + 
Sbjct: 24469 KEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKI 24528

Query: 362   YV 363
             ++
Sbjct: 24529 HL 24530



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 636   PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSI---EASSRFTSIFRFG 692
             PP+F +PL + TA  G  + F   I    +P   + W K+GQ I   +   ++T     G
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 25249

Query: 693   YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
                L + S+   D  EYT  A +  G    KA L VT
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 25286



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 71    PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR---KKAPLVECNKYSMRYNEQTG 127
             PP F     N     G N +F   +  +P P V+W +   K  P     KY+  +    G
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT--FESDKG 25249

Query: 128   DVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
                L I  +   D+ EYT  ARN+YGE  C
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSC 25279



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 12/172 (6%)

Query: 3704  NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGFIALDIDYIYA 3762
             N +  EG  V F+ RV  +  PT++  W  +G+P + G  +  +++   + AL I     
Sbjct: 25306 NAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLP 25363

Query: 3763  RDAGEYTCRATNKWGSATTTAKITCS----AKRDIVLESQLPQGMSGEKIKELERGRISD 3818
              D G Y   ATN  GS +  A +        K++   + +  + +  +  K L    I  
Sbjct: 25364 EDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILS 25423

Query: 3819  APKEEPIVSTPPKFITQ--IKSHTVEESEGVRFECRV---EPKEDPKLRIEW 3865
               +  P+     + + +  +       ++ V+ E R+   E KE+ KLR+ +
Sbjct: 25424 GTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLRMPY 25475



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 48/245 (19%), Positives = 84/245 (34%), Gaps = 19/245 (7%)

Query: 522   ITWQKDGVPIIPNPELRIHTDG-GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             +TW KDG  +  N   + H    G   L I     SD   Y C      G++ T  +   
Sbjct: 26252 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 26311

Query: 581   XXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFI 640
                       K +H  + +K+                  +  P  P    + +   P  +
Sbjct: 26312 QAF-------KSIH-EKVSKISETKKSDQKTTESTV-TRKTEPKAP----EPISSKPVIV 26358

Query: 641   VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLS 700
               L+  T        F   ++  G+P     W K+G++I    ++      G   L++  
Sbjct: 26359 TGLQDTTVSSDSVAKFA--VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 26416

Query: 701   LNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQE 760
              +  DSG YTC   ++ G   +   L +     I+ T     + Q   ++    K   QE
Sbjct: 26417 TDTSDSGLYTCTVKNSAGSVSSSCKLTI---KAIKDTEAQKVSTQKTSEITPQKKAVVQE 26473

Query: 761   SIEEQ 765
              I ++
Sbjct: 26474 EISQK 26478



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F     + +  +G  A+F+ K+ G P P   W      +V    + +   E  G  SL
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED-GTQSL 1469

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            +I    P D GE+T  A+N+ G +  SV +  E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1502



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 87/362 (24%), Positives = 150/362 (41%), Gaps = 45/362 (12%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            +P  + +  S + V EG  V  E K   V+  +++  W K+GQ V    R   + D    
Sbjct: 2308 RPIAILQGLSDQKVCEGDIVQLEVK---VSLESVEGVWMKDGQEVQPSDRVHIVIDKQSH 2364

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L I D+  ED+G Y+   +  +G    S R++  S  D++        L+ + V+E   
Sbjct: 2365 MLLIEDMTKEDAGNYSF-TIPALGLS-TSGRVSVYSV-DVITP------LKDVNVIEG-- 2413

Query: 1563 KYHRTDMVDEVTTQAPICTTS---LKNVEIKEGQRAHFERRLIPVSDATLKVEWYH--NN 1617
                T  V E     P  T+    L + +IK   R    + ++  +   L +   H  + 
Sbjct: 2414 ----TKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVINRTHASDE 2466

Query: 1618 KPLKSGSRFTETN-NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS----- 1671
             P K      ETN N     + I+  L + + T T   +  + E   SGI ++ +     
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV-ELSHSGIDVLWNFKDKE 2525

Query: 1672 -KKSIYLESQHEGALPRLNQL----EDTSKYQRHSAQD----EVITQAPVFTMPMKDIRV 1722
             K S   + +  G + +L  L    +D  KY  ++ ++    ++       + P+ D  V
Sbjct: 2526 IKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVAGGAISKPLTDQTV 2585

Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782
            AE+Q A FE     V +P  + EWLR+G  +  +N + +  D     L +     +D G 
Sbjct: 2586 AESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2642

Query: 1783 YT 1784
            YT
Sbjct: 2643 YT 2644



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYIS-LDMLSLNIQDSGEYTCRAVSATGVAETKA 724
            P ++ +W K G+ I  S +  SI    YIS L++L   + D GEYTC+A +  G     A
Sbjct: 4364 PNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 4422

Query: 725  VLHVT 729
             L VT
Sbjct: 4423 TLTVT 4427



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 76/367 (20%), Positives = 143/367 (38%), Gaps = 39/367 (10%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V+   P FT  ++D    E      +  +     P   V+W ++G  I+ S       D 
Sbjct: 5516 VLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKADG 5572

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
                L +K     D G YTC    + G   TS  L ++ +     E +    L  ++ +E
Sbjct: 5573 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR-----EIKLVRPLHSVEVME 5623

Query: 1826 -DSSRYQRR-EDVEVAVNQAPRFITQLNGPT-KLSEGQSAH----YECRIEPYPDPNMRV 1878
             +++R++    + ++  N   +    L  P  ++ E    H    + CR++     + + 
Sbjct: 5624 TETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQA 5683

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAA-LDILTVYGEDSGEYTCK-AINNLGQAVSSIRLNV 1936
                   V  S H        G    L  +TV   ++  + C+ +  ++          +
Sbjct: 5684 -----ANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKL 5738

Query: 1937 QSKESIIRDSQ---HESALEKIQYLEDDSRYKRAVQD-----DSFVVEKP-QFGKPIKNA 1987
            +  + ++  S+   H   L  ++ LED    +   +D     + FV E P +F KP+++ 
Sbjct: 5739 EPSDKVVPRSEGKVHTLTLRDVK-LEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQ 5797

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
             V EG    LE  ++  N    +V+W+ NG  + +  +++   D     L I     ED 
Sbjct: 5798 TVEEGATAVLECEVSREN---AKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDI 5854

Query: 2048 GTYMCKA 2054
             TY C A
Sbjct: 5855 KTYTCDA 5861



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/66 (25%), Positives = 34/66 (51%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G   +   ++ G P P +TW K G+ L+   + ++I       L+++   ++D G Y + 
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11485

Query: 340   AENPNG 345
             A+N +G
Sbjct: 11486 AKNSSG 11491



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 21/69 (30%), Positives = 35/69 (50%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G +      + G P P V+W K+G  L  +   ++    N  TL + +  + DSG Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869

Query: 337   TLLAENPNG 345
             T+ AEN +G
Sbjct: 12870 TITAENSSG 12878



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 4/108 (3%)

Query: 467   ARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLN--VREGEPVVLNARAVGTPTPRIT 523
             A N++GE      + V+ ++ VVAP   ++    L    +E     L     G P P ++
Sbjct: 13460 AENENGEGT-PSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13518

Query: 524   WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             W+K   P+  +  + + +    +TL +   + SDA  Y  T +NVAG+
Sbjct: 13519 WKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGT 13566



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/82 (29%), Positives = 37/82 (45%)

Query: 4512  VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
             + PS  L     NV + + +++D    G     V W K+G+ ++   R  +       +L
Sbjct: 18896 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL 18955

Query: 4572  LILEAYPQDSGKYECVAINSAG 4593
              I EA  +D G YE    NSAG
Sbjct: 18956 SIKEASKEDVGTYELCVSNSAG 18977



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 12/133 (9%)

Query: 2366  EIPEPVTR------QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI 2419
             EI EP+T       Q P F + L+N+ N++    A   C++   G P   V+W+R  K I
Sbjct: 24415 EISEPITPKSDVPIQAPHFKEELRNL-NVRYQSNATLVCKV--TGHPKPIVKWYRQGKEI 24471

Query: 2420  EDSSRITKTHDF--GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE 2477
                    +  +F  GY  + I+ V D+D  VY  RA+N  G               I L 
Sbjct: 24472 IADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL- 24530

Query: 2478  TQHPEGMKKIQKL 2490
              +  EGM  +  L
Sbjct: 24531 PKTLEGMGAVHAL 24543



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 768   QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-- 825
             Q P F   L++L    +  NA    ++T    P   V+WY+ G+ I A      I  F  
Sbjct: 24429 QAPHFKEELRNLNVRYQS-NATLVCKVT--GHPKPIVKWYRQGKEIIADGLKYRIQEFKG 24485

Query: 826   GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             GY  L I  +  +DA  Y VRA N+ G    TAS+ V
Sbjct: 24486 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F   ++ ++ V +G  V    RV   G PT  + ++ +G    +        +    
Sbjct: 103  PPNFVQRLQ-SMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            +L I   Y  D+G Y+  ATN  G AT+TA++    + ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FVQ L +   V +G  + L+ R+   G PT  V+++ +G  +     F+   +    +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I  A   D+G Y+V A N +G A TS    +++  + V   + +  +   Q+ E    
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRA-TSTAELLVQGEEEVPAKKTKTIVSTAQISESRQT 219

Query: 1297 RTKQ 1300
            R ++
Sbjct: 220  RIEK 223



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 42/183 (22%), Positives = 73/183 (39%), Gaps = 13/183 (7%)

Query: 4622 PPEIIEPLKDKIVAE----GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
            P + ++ +KD I+ E    G +  F C +V        W K    I+ S   +      +
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRFIADGKD 4675

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
              L I +    D G+Y CV        T  AKL V   ++       T   ++ V +GQP
Sbjct: 4676 RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV---EELPVRFVKTLEEEVTVVKGQP 4732

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE--GNNAVLLIGNTYEEDTGTFTCRA 4795
                 ++    +  + W ++G ++ E P  +++    G    L I +  + D GT+T   
Sbjct: 4733 LYLSCELNK--ERDVVWRKDGKIVVEKPG-RIVPGVIGLMRALTINDADDTDAGTYTVTV 4789

Query: 4796 TTA 4798
              A
Sbjct: 4790 ENA 4792



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 25/77 (32%), Positives = 36/77 (46%)

Query: 494  VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
            V+  + L V+ G  + L A   G P P+ITW K  + +  +  + I      ST+ I  +
Sbjct: 7197 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS 7256

Query: 554  KASDAAWYQCTAQNVAG 570
            K SD   Y   A NV G
Sbjct: 7257 KRSDTGTYIIEAVNVCG 7273



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 5/106 (4%)

Query: 4511  IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             ++PP+F L      V +G+ +++D    G     V W K+   ++   R      +    
Sbjct: 15648 VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSL 15707

Query: 4571  LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
             L I +A  +D G Y     NSAGEA      +V      DKP P T
Sbjct: 15708 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV-----LDKPGPPT 15748



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 4120  VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTG 4178
             VT + GE A+  C++ G P P + W   G  ++   +YK++ DG  H   +    Q D G
Sbjct: 24045 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEG 24104



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGYVALDIASVRAED 1112
            +I+EG    F  ++         + WY +GK+I    R Q  +   G  +L I  V  ED
Sbjct: 1255 RILEGMGVTFHCKMSGYP--LPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312

Query: 1113 SGVYTVVARNAAGEAQLSASMTVE 1136
             G+YT  A N  G A  S  + VE
Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF-NFGYVSLNIMHLRAEDAGS 842
            EG    F  +++    P  ++ WYKDG+ I    R    F   G  SL I  +  ED G 
Sbjct: 1258 EGMGVTFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315

Query: 843  YTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
            YT  A N  G AI +  + V   + + A   IP
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP 1348



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 3/87 (3%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V   Q   F  +L       +   A +EC      +P ++V+WY +G  +  G +YR  +
Sbjct: 2122 VQAKQLITFTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHS 2178

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINN 1924
            D     L ILT+   D+ +Y+C  + +
Sbjct: 2179 DRKVHFLSILTIDTSDAEDYSCVLVED 2205



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 13/136 (9%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P  K  I + + +  G  A F   ++   +  +R +W K GR +  S + +   +    +
Sbjct: 4337 PVIKRKI-EPLEVALGHLAKFTCEIQSAPN--VRFQWFKAGREIYESDKCSIRSSKYISS 4393

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I    V D G YTC+A N  G  + +A LT+            PGG +K++ L    +
Sbjct: 4394 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTV----------PGGEKKVRKLLPERK 4443

Query: 1029 YSKRTEEEVKITQKPR 1044
               + E  +K   + R
Sbjct: 4444 PEPKEEVVLKSVLRKR 4459



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 34/117 (29%), Positives = 49/117 (41%), Gaps = 6/117 (5%)

Query: 246   GESDVQISTEIDRSLGPVSPPKI---AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
             GESD     E       + PP++   A   R   ++ G   +    + G P P+VTW K 
Sbjct: 10699 GESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKE 10758

Query: 303   GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC-IVTSGYLAVESP 358
              +      K  I  T   + L +RN    D G Y+L  ENP G   V+   L ++ P
Sbjct: 10759 DRDA--PTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKP 10813



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 18/59 (30%), Positives = 33/59 (55%)

Query: 287   VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             + + G P P+ +W K G+ +  S+  +I +T   + L ++   + D+G YT+ A NP G
Sbjct: 13904 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 5/104 (4%)

Query: 4511  IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             ++ P       + +V  GQ ++++  ++G     + W K+G  ++   R  + +     T
Sbjct: 16730 VIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16789

Query: 4571  LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             L I E +  D G+Y     N  G+     E V     T DKP P
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKTASIEIV-----TLDKPDP 16828



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G  A+  +   G P P +TW +       ++K +I    N+T L + N  ++D+G Y
Sbjct: 17539 VRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAGKY 17596

Query: 337   TLLAENPNG 345
              L  EN +G
Sbjct: 17597 ILKLENSSG 17605



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/125 (20%), Positives = 51/125 (40%), Gaps = 1/125 (0%)

Query: 4690  EGDYKCVAYNSAGRVTVAAK-LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             E  ++  AYN  G+       + V   D         P     +  G+  + +  +  + 
Sbjct: 17783 EYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRP 17842

Query: 4749  KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +P I W+++G  + +T    +     + VL I    ++D G +T  AT +AG    +  +
Sbjct: 17843 RPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 17902

Query: 4809  VVKSK 4813
             +V  K
Sbjct: 17903 IVLEK 17907



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 4622  PPEIIE---PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             PPEI     P     V  G  ++    I GKPLP V   +    +K +  F    TA+  
Sbjct: 19976 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20035

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAG 4702
             T+ + E+   D G Y+  A NS+G
Sbjct: 20036 TINLKESVTADAGRYEITAANSSG 20059



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 6/135 (4%)

Query: 4578  PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
             P D  ++  +A N+ G     ++    +  T+D+  P        PE  + L   I+  G
Sbjct: 21423 PGDRYEFRIIARNAVGTISPPSQSS-GIIMTRDENVPPI--VEFGPEYFDGL---IIKSG 21476

Query: 4638  QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
             +++     + G+P+P V W+K    I+     +++      +L + +A  +  G Y   A
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 21536

Query: 4698  YNSAGRVTVAAKLKV 4712
              N++G      K+KV
Sbjct: 21537 KNASGSAKAEIKVKV 21551



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 4/110 (3%)

Query: 1703  QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
             + +V  QAP F   ++++ V     A    ++   G PK  V+W R G  I A      +
Sbjct: 24423 KSDVPIQAPHFKEELRNLNVRYQSNATLVCKV--TGHPKPIVKWYRQGKEIIADGLKYRI 24480

Query: 1763  HDF--GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
              +F  GY  L +  V  +D+  Y  RA N+ G    +++L V+  A + L
Sbjct: 24481 QEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL 24530



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 16/115 (13%)

Query: 4080 HMKSIEK--IREMEASW-QVTPEQVVEESKARCPPVFVSLPDAVT-----------VEEG 4125
            H+ S E+  I+E+E    + T E+++EE       V +S  +AV            + EG
Sbjct: 1200 HISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEG 1259

Query: 4126 EWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYDTG 4178
                F C+++G+P P++ W  +G  I +G RY++ +  DG     IP     D G
Sbjct: 1260 MGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1314



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 639  FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF-RFGYISLD 697
            F + +K+   +EG  + F  ++   G P  KI W K+G+ I+   R+   F + G  SL 
Sbjct: 1247 FDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLR 1304

Query: 698  MLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            +  +  +D G YT  A +  G A     L+V P A +   +  P TL+ + ++   S
Sbjct: 1305 IPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP-TLEPVSRIRSLS 1360



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLR--GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            P F++   + R  + G A FE +L   G+PT VV W     PL   N+  +R   + G  
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR--LRMINEFGYC 1714

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL        D G  TC A N+YG
Sbjct: 1715 SLDYGVAYSRDSGIITCRATNKYG 1738



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 4/123 (3%)

Query: 1147 HRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGD 1206
            H+G Y     + +S       ++  + ++ PV  + +  P  V+ G      C ++    
Sbjct: 4308 HQGEYV-CEALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSA-- 4363

Query: 1207 PTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
            P +R +WF  GR +    +          +L+I+     D GEYT +A N  GS   +A 
Sbjct: 4364 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 4423

Query: 1267 VRV 1269
            + V
Sbjct: 4424 LTV 4426



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 14/148 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMV-VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            ++WF +G+ I  S +  ++ A G+  +L+I      D G Y C       +A ++V+   
Sbjct: 5195 VKWFKDGEEIVPSPKY-SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARL 5253

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            +   K +KP +   +        G++AHFE   + + +PD+  +W   GQP+  S   + 
Sbjct: 5254 I---KVEKPLYGVEVFV------GETAHFE---IELSEPDVHGQWKLKGQPLTASPDCEI 5301

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            + D    +L +   Q   +GE   +A N
Sbjct: 5302 IEDGKKHILILHNCQLGMTGEVSFQAAN 5329



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 49/208 (23%), Positives = 91/208 (43%), Gaps = 24/208 (11%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V ++ G+ A ++  L     + + +EW+  GK +E S ++       +  L +   K  D
Sbjct: 5708 VTVTAGETATFDCEL---SYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLED 5764

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            +G     A +    A + VK   V+        FT  +++ + +++G +A  EC V    
Sbjct: 5765 AGEVQLTAKDFKTHANLFVKEPPVE--------FTKPLED-QTVEEGATAVLECEV---S 5812

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF-TR 3236
              + K++W+ NG  +  S + + V+D     L I      D   Y C A     +DF T 
Sbjct: 5813 RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA-----KDFKTS 5867

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELE 3264
              +N       ++E L+P +  ++RE E
Sbjct: 5868 CNLNVVPP---HVEFLRPLTDLQVREKE 5892



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 9/122 (7%)

Query: 3933 VPRGMKRSEALTQMEATIKKYTSEVYLTEDDLY---DVDKKQPP-RFVTQIQSQTSLVEM 3988
            VPR   +   LT  +  ++    EV LT  D     ++  K+PP  F   ++ QT + E 
Sbjct: 5745 VPRSEGKVHTLTLRDVKLED-AGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQT-VEEG 5802

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
             T   EC+   V   N KV+WF NG  +L   ++  + D     +      PED   Y C
Sbjct: 5803 ATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 5859

Query: 4049 RA 4050
             A
Sbjct: 5860 DA 5861



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/60 (36%), Positives = 31/60 (51%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W KDG+ V+AS R+T   +     L +      DAG YT    N +G AT S N+ ++
Sbjct: 7921 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 7980



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 36/171 (21%), Positives = 67/171 (39%), Gaps = 12/171 (7%)

Query: 194  QGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIS 253
            QGY  E+ R  +            T  F V+  +   + E  FR       +GES+  + 
Sbjct: 8830 QGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYE--FRVKAVNE-IGESEPSLP 8886

Query: 254  TEI---DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL---- 306
              +   D  + P    +++ +    K++ G        ++G P P++ W KN   +    
Sbjct: 8887 LNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPT 8946

Query: 307  --INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
              +   K E+  +   T L +    + D G YT+ A N  G +  + ++ V
Sbjct: 8947 DALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 8997



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 6/83 (7%)

Query: 1058  GQSAHFEARVE--PQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGV 1115
             GQ+    ARV+  P+ D+T T E    GK +    R+    D   V L I      D G 
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKE----GKVLVREKRVDLIQDLPRVELQIKEAVRADHGK 11481

Query: 1116  YTVVARNAAGEAQLSASMTVETR 1138
             Y + A+N++G AQ SA + V  R
Sbjct: 11482 YIISAKNSSGHAQGSAIVNVLDR 11504



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL--KSTFDFGLVTLSINSLRNDDSGI 2714
             G+   ++A +  +  P   I+W K    L+  ARL  KST DF   +LS+      DSG 
Sbjct: 16061 GESFKVDADIYGKPIPT--IQWIKGDQELSNTARLEIKST-DFA-TSLSVKDAVRVDSGN 16116

Query: 2715  YTCKATNLLGEAVSTASIKIEDR 2737
             Y  KA N+ GE   T ++K+ DR
Sbjct: 16117 YILKAKNVAGERSVTVNVKVLDR 16139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
             G +   +  + G P P + WT+    L  C K S++Y  +    + +IK     D G+YT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKR--ATAVIKFCDRSDSGKYT 22622

Query: 146   CTARNQYGEAICSVYIQ 162
              T +N  G    SV ++
Sbjct: 22623 LTVKNASGTKAVSVMVK 22639



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/106 (31%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 368   SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
             S+Y     + E  ERIEI +  LA    K    R    G   R    V+GRP P +TW  
Sbjct: 22929 SEYSESIAEIEPVERIEIPDLELADDLKKTVTIR---AGASLRLMVSVSGRPPPVITW-- 22983

Query: 428   NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
               +Q  D  +  I+        L++  V   D+G  T  A N+SG+
Sbjct: 22984 -SKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGK 23028



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033
            + P F +P+++  V EG     EA ++    P   V W+ +G+ +        + ++  G
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
               L I      ++G Y  KATN  G+A +T+ + V A++
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFD 1366
            QAP F++ L ++  +EG+    E  +   G     V WF +G+ I T      + ++   
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
               L + +V   +SG Y+ +ATN  G+A ++  L V A+
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/97 (32%), Positives = 48/97 (49%), Gaps = 7/97 (7%)

Query: 2944 KIEWYFNGKVLEQGSRFKLTSDF---GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            KI WY +GK ++ G R+++  DF   G  +L +  V   D GIYT  A N +G A  S  
Sbjct: 1275 KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGK 1332

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLED-SLRKEP 3036
            +Y      L   T  P   E + +I++L   S+ + P
Sbjct: 1333 LYVEPAAPLGAPTYIPT-LEPVSRIRSLSPRSVSRSP 1368



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 37/118 (31%), Positives = 50/118 (42%), Gaps = 5/118 (4%)

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            +P  IE     + P     + S + + +G  AHF  RV    DP    +W+ NG KI   
Sbjct: 2019 KPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERS 2075

Query: 2156 HR-YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQ 2212
             R Y    +     L I    AEDS + M KA N  GE  +   L V   + +I  TQ
Sbjct: 2076 DRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA-KQLITFTQ 2132



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 42/175 (24%), Positives = 69/175 (39%), Gaps = 13/175 (7%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            + +K  +D    E     F+  V+    P V WF  + +I+    H+ LV+E   H LM+
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLML 2807

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             N++ SD+G  T V     G+   +C+  +     V      +    + V E +      
Sbjct: 2808 QNISPSDAGEYTAVV----GQ--LECKAKLF----VETLHITKTMKNIEVPETKTASFEC 2857

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
                   P + W K+GV I  + + +I   G    L I      D+A Y     N
Sbjct: 2858 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2911



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 6/97 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P   TP+ D +S +EG   H    +     +   V W  + + V +  +     +     
Sbjct: 4243 PMIHTPLVDTVS-EEGDIVHLTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYT 4297

Query: 969  LTIKSVTVHD-AGHYTCRAYNAIGQATTSANLTIVTK 1004
            L I  V   D  G Y C A N  G+  TSA LT+V +
Sbjct: 4298 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 4334



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 1314  SRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDL 1372
             S A+ ++ TV+ GTNV L+  +   G     V W  +G  +K     + A + +   L+L
Sbjct: 12801 SVAMKSLLTVKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 12858

Query: 1373  LSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
              SV  +DSG YT  A N  G    +  L+V+ K
Sbjct: 12859 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/71 (35%), Positives = 34/71 (47%)

Query: 2004  VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
             +  PT  V W+ +  P++Q  R           L I  A  ED G Y+ K TN+ GEA+ 
Sbjct: 15675 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 15734

Query: 2064  TSSVKVDAKSG 2074
             T +V V  K G
Sbjct: 15735 TLNVIVLDKPG 15745



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 20/66 (30%), Positives = 31/66 (46%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G   +  + ++G P P  +WF  G +L  S +  + T      L +R T   D+G YTL 
Sbjct: 23256 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23315

Query: 340   AENPNG 345
              +N  G
Sbjct: 23316 LKNVTG 23321



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 48/184 (26%), Positives = 80/184 (43%), Gaps = 10/184 (5%)

Query: 3774  NKWGSATTTA-KITCSAKRDIVLESQLPQGMSGEKIK-ELERGRISD--APKEEPIVSTP 3829
             NKW S TT   + T  + ++++   +    +  E +  E E   IS+   PK +  +  P
Sbjct: 24372 NKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAP 24431

Query: 3830  PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYR-TVYDMGFV 3887
               F  ++++  V         C+V     PK  ++WYR GK ++  G +YR   +  G+ 
Sbjct: 24432 -HFKEELRNLNVRYQSNATLVCKVTGH--PKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24488

Query: 3888  SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQME 3947
              L I  V  +D+  Y  RA N  G     A++   ++P  I   +   GM    AL    
Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTLEGMGAVHALRGEV 24547

Query: 3948  ATIK 3951
              +IK
Sbjct: 24548 VSIK 24551



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/84 (27%), Positives = 35/84 (41%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F Q  ++    +G  A FE  + G P P VSW R    +       ++ +   G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155
            I  +   + G Y+  A N  G+A
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA 89



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            T  P F+  L+    + +G     + RV      T  V++Y +G +I S+   Q   +  
Sbjct: 101  TAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQISQEGD 157

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
              +L IA    EDSG Y+V A N+ G A  +A + V+    +
Sbjct: 158  LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 1/82 (1%)

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
            V EG+ A+F+ ++T   +P + W   G LI ++  F++ ++G +  L I +    DTG  
Sbjct: 1806 VLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIH-YLDIVDCKSYDTGEV 1864

Query: 4792 TCRATTAAGQVETSAKLVVKSK 4813
               A    G +E   KL ++ +
Sbjct: 1865 KVTAENPEGVIEHKVKLEIQQR 1886



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 4/99 (4%)

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            FK  +I    + + P   + +Q+   + +G  AHF  R+  VG P  + EW++N   IE 
Sbjct: 2018 FKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIER 2074

Query: 2422 SSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S RI     +     + I  V  ED    M +A N+ GE
Sbjct: 2075 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE 2113



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 3284 FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343
            F  ++QDV    +   A FE       +P +KV+W+ +G ++  G +YR   D  +  L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 3344 ILYCYEENSGEYECV 3358
            IL     ++ +Y CV
Sbjct: 2187 ILTIDTSDAEDYSCV 2201



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 10/96 (10%)

Query: 771  QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-S 829
            +F + ++D+  L++ R A FE +   VS+P + V+W KD + +  + RI  I    YV  
Sbjct: 3013 EFRKHIKDIKVLEKKR-AMFECE---VSEPDITVQWMKDDQELQITDRI-KIQKEKYVHR 3067

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            L I   R  DAG YTV A    G  +STA + V  R
Sbjct: 3068 LLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3099



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERD-SGI 2983
            EG ++HL   +    +    + WYF  K++    +FK   D    TL +  V   D  G 
Sbjct: 4256 EGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4311

Query: 2984 YTCKAYNKRGEAFTSS 2999
            Y C+A N  G+  TS+
Sbjct: 4312 YVCEALNDSGKTATSA 4327



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 4/125 (3%)

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
            TE +  +   + + D+ +  T  ++ + ++A AP   +  +  +V  G + +F C +   
Sbjct: 4305 TEDHQGEYVCEALNDSGKTATSAKLTVVKRA-APVIKRKIEPLEVALGHLAKFTCEIQSA 4363

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P     WF   R+I +  + K  +  S    +L I    + D G  TC A N+ G  +  
Sbjct: 4364 PNVRFQWFKAGREIYE--SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT 4421

Query: 478  CRLNV 482
              L V
Sbjct: 4422 ATLTV 4426



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVR----FECRVEPKEDPKLRIEWYRNGKLLP 3873
            +AP    + + P KF+ +IK   + ESE V     FEC V P         W ++G  + 
Sbjct: 4606 EAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPST---AITTWMKDGSNIR 4662

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
               ++R + D     L I+ V   D+GEY C       E  + A +  ++LP
Sbjct: 4663 ESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP 4714



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 9/100 (9%)

Query: 2222 QLEAQGHSTRIE--VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
            QL A+   T     V+EP   P  F   L   T V EG TA  EC+V      N +++++
Sbjct: 5769 QLTAKDFKTHANLFVKEP---PVEFTKPLEDQT-VEEGATAVLECEVSR---ENAKVKWF 5821

Query: 2280 HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKA 2319
             NG  +  + ++ I  D     L I  C PED   Y+  A
Sbjct: 5822 KNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)

Query: 4613  KPQT-KAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             KP T K   APP +    +DK+ +  G+A   + +  GKP P V W+K +  +       
Sbjct: 10310 KPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTH 10369

Query: 4671  MSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
             +  T     L   +A   D G Y  V  NS G
Sbjct: 10370 IKTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/112 (24%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 245   VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
             +G  D  I  E    L P S     +      ++ G   +F   + G P P   W  +G 
Sbjct: 10993 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGS 11052

Query: 305   RLINSNKHEIITTHNHTT-LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
               I +++H  + T N ++ L ++N  + D+G Y +   N  G    + +L V
Sbjct: 11053 E-IKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 21/69 (30%), Positives = 32/69 (46%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
             V  G+ ++     +G+P P V W+K +  +K +       T +   L I +A  ED G Y
Sbjct: 15662 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15721

Query: 4694  KCVAYNSAG 4702
                  NSAG
Sbjct: 15722 VVKLTNSAG 15730



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 2/90 (2%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P  +  F +     G + K E  + G P P ++WT+   PL +  + ++   +     +L
Sbjct: 16733 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV--TDSLDLTTL 16790

Query: 132   LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              IK+    D G+Y  T  N  G+   S+ I
Sbjct: 16791 SIKETHKDDGGQYGITVANVVGQKTASIEI 16820



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/78 (28%), Positives = 37/78 (47%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  R E +  G+PLP I+W R +  I+ S   +I     K++LI++     D   +   A
Sbjct: 17144 ETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRA 17203

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N  G+     N+ V ++
Sbjct: 17204 SNVAGSKSFPVNVKVLDR 17221



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 4620  NAPPEIIEP-LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
             +AP   ++P  KD IV   G+       I GKP+P V W K G +L + +   ++  T  
Sbjct: 18206 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18265

Query: 4677  EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             + TL + +    D G Y     N  G  ++   +KV
Sbjct: 18266 KTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ GA     V   G P P V W K    L    +  + TT + T+L + N  ++DSG Y
Sbjct: 19701 VKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYVDTTDSRTSLTIENANRNDSGKY 19758

Query: 337   TLLAEN 342
             TL  +N
Sbjct: 19759 TLTIQN 19764



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 4091  EASWQVTPEQVVEESKARCP-PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
             E+ W    E +  +S      P F      + V     A   C+VTGHPKP V W   G 
Sbjct: 24410 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24469

Query: 4150  TIV-NGSRYKL-TYDGMYH 4166
              I+ +G +Y++  + G YH
Sbjct: 24470 EIIADGLKYRIQEFKGGYH 24488



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 10/133 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP FV ++QS T     + ++   Q+   G P   V+++ +G  +     F    +    
Sbjct: 103  PPNFVQRLQSMTV---RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP-KHMKSIEKIREM 4090
            ++     YPEDSG Y   ATN  G   + A +   G      + ++P K  K+I    ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EEEVPAKKTKTIVSTAQI 213

Query: 4091 EASWQVTPEQVVE 4103
              S Q   E+ +E
Sbjct: 214  SESRQTRIEKKIE 226



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            +E P+  + I++  V +G   H    +    DP    EWY NG  +++  R    +    
Sbjct: 2029 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDN 2086

Query: 2035 VA-LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            V  L I    AED+ + M KA N  GE  + + + V AK
Sbjct: 2087 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG+ + +      +  PT  V W  +G+ V    R     D     L++  +  AD G
Sbjct: 7901 VIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAG 7958

Query: 1249 EYTVRAVNHLGSAHTSAIVRVI 1270
             YT+   N LGSA  S  V+VI
Sbjct: 7959 IYTITLENKLGSATASINVKVI 7980



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 2/61 (3%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDI-ASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            TV W+ +GK++ +++R+   +D     L++  SVRA D+G+YT+   N  G A  S ++ 
Sbjct: 7920 TVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DAGIYTITLENKLGSATASINVK 7978

Query: 1135 V 1135
            V
Sbjct: 7979 V 7979



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/64 (34%), Positives = 31/64 (48%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V W  +GK +    R+   ND     LE+    + DAG+YT    N+ G AT S  ++V 
Sbjct: 7921 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 7980

Query: 3651 GRQG 3654
            G  G
Sbjct: 7981 GLPG 7984



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/74 (29%), Positives = 40/74 (54%)

Query: 4523  VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
             V + +G+  RL+  V+G  P  + W K+GK+++   + +I   D +  L+  ++  +DSG
Sbjct: 14974 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15033

Query: 4583  KYECVAINSAGEAR 4596
              Y   A N  G A+
Sbjct: 15034 AYTLTATNPGGFAK 15047



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 782   LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
             +Q G +   E  +  +  P   + W KDG P+  ++R+          L+I     +D G
Sbjct: 17826 IQAGEDLKIEIPV--IGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 17883

Query: 842   SYTVRAVNKLGEAISTASIRV 862
              YTV A N  G A    S+ V
Sbjct: 17884 KYTVTATNSAGTATENLSVIV 17904



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 19/64 (29%), Positives = 30/64 (46%)

Query: 284   QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
             +  V   G P+  V W K+GQ L  + +  + ++   T+L ++   K D G Y L   N 
Sbjct: 18916 KIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 18975

Query: 344   NGCI 347
              G I
Sbjct: 18976 AGSI 18979



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/86 (25%), Positives = 47/86 (54%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQK--PRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             + PP+I  K  P ++  ++ G++ +  + +SG P P+VT  ++G  L  + +     T  
Sbjct: 19974 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 20033

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
             + T+ ++ +  +D+G Y + A N +G
Sbjct: 20034 NLTINLKESVTADAGRYEITAANSSG 20059



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 3403  SMVRRKDTSVEEE--KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
             S  RR   S++ +   G+AP     + ++   + GE A    ++     P++K  WY  G
Sbjct: 24017 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTT-KLGEAAQLSCQIVGRPLPDIK--WYRFG 24073

Query: 3461  KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             K L    +++   D     L +     ED G Y C A N  GE  T++ + +Q
Sbjct: 24074 KELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/60 (28%), Positives = 32/60 (53%)

Query: 1077  VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             ++WY  GK++  + + +   D     L + +   ED GVYT +A N  GE + S+ + ++
Sbjct: 24067 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/64 (31%), Positives = 32/64 (50%)

Query: 666   PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAV 725
             PT +++W  NG  ++ SS+       G ++L++L  +  DSG Y     +  G A   A 
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYAT 25963

Query: 726   LHVT 729
             L VT
Sbjct: 25964 LDVT 25967



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 19/53 (35%), Positives = 28/53 (52%)

Query: 2538  PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             P+   +WY NGVEL+  S+   T+  G +TL+I     +D+G Y     N  G
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKG 25956



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 82/413 (19%), Positives = 159/413 (38%), Gaps = 55/413 (13%)

Query: 1017  LEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMT 1076
             LEK    E+ ++ S+ +EE     +   F   +     I EGQ    +A +   +D    
Sbjct: 26519 LEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMS----INEGQRLVLKANIAGATD---- 26570

Query: 1077  VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             V+W  NG ++T++   +         L I      D G+ T +++   G  +    +T+ 
Sbjct: 26571 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 26630

Query: 1137  TRSSIDTSSIHRGLYEKTRHIEESKFV-----EPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
                S   + I +   +     +   F      EP  +IE    + P+ +   S+   +S 
Sbjct: 26631 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISI---SSNVSISR 26687

Query: 1192  GKNIH-LECRLEPMGDP---TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADT 1247
              +N++ LE R   + D    T++ + F    S T         +    + +++  TS DT
Sbjct: 26688 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEP--SREVVLRTSGDT 26745

Query: 1248  ---GEYTVRAV-----------NHLGSAHTSAIVRV------------IERSDIVTDTQN 1281
                G ++ ++V           +   S+  S++  +            ++ S +   + +
Sbjct: 26746 SLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSS 26805

Query: 1282  EQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQT 1341
                I  +  LE +   +K ++  I  +  P+      +I   EG  + + C     G+ T
Sbjct: 26806 FMGISNMTQLESST--SKMLKAGIRGIP-PKIEALPSDISIDEGKVLTVACAF--TGEPT 26860

Query: 1342  MRVEWFCNGKPIKTGH--RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
               V W C G+ I +    RF      D   L ++ V  +D G+YT    N+ G
Sbjct: 26861 PEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +TTQAP  T  L++V + EG  A FE  +   PV +    V W+ + + + + +      
Sbjct: 1    MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQI 56

Query: 1631 NF--GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            +F  G   L I +    +SG Y+ +A N  G+A ++   +V ++
Sbjct: 57   SFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 46/180 (25%), Positives = 69/180 (38%), Gaps = 16/180 (8%)

Query: 396  KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
            K  ++ +V E K   F+C V+    P + W  N  +I      KI+V +   H L+I N 
Sbjct: 2840 KTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVV-QGKLHQLIIMNT 2897

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARA 514
            +  DS            E  F C  + +     V P  +      +N  E + +      
Sbjct: 2898 STEDSA-----------EYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEV-T 2945

Query: 515  VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            V        W K+GV I    + ++ T     +L+I      DAA Y   A   A STAT
Sbjct: 2946 VNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA-GKATSTAT 3004



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/90 (26%), Positives = 37/90 (41%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P+  +K++P  V     A+F  E    P    +W++    I  S    I +    S L I
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4396

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +  V D   +   A N  G+  C+A L V
Sbjct: 4397 LRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/106 (22%), Positives = 53/106 (50%), Gaps = 3/106 (2%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E ++ P+++ +W+  G+ + +  +  + S     +L+++     D G YTCKA N+ G  
Sbjct: 4359 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 4418

Query: 2996 FTSSTVYCT--SKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQ 3039
              ++T+  T    +  + +    +  E  E++  L+  LRK P ++
Sbjct: 4419 SCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-LKSVLRKRPEEE 4463



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 7/93 (7%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            P EFT    D  + E ++A  EC    V+  + +V+WF NG  +L   + + + D     
Sbjct: 5787 PVEFTKPLEDQTVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRK 5843

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I      D   YTC A     +   SC L V
Sbjct: 5844 LVIHDCTPEDIKTYTCDAK----DFKTSCNLNV 5872



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 4/74 (5%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F  PL++++ +RE E A FE  L+     N KV+W+ +G  +K G ++         IL 
Sbjct: 5879 FLRPLTDLQ-VREKEMARFECELSRE---NAKVKWFKDGAEIKKGKKYDIISKGAVRILV 5934

Query: 3482 ISPTYPEDSGEYLC 3495
            I+    +D  EY C
Sbjct: 5935 INKCLLDDEAEYSC 5948



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 8/91 (8%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH--- 318
            P  PP I  K    +++EG +     ++ G P P +TWFK   +  ++ +  +  TH   
Sbjct: 9617 PDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNK 9675

Query: 319  ----NHTTLRVRNTQKSDSGHYTLLAENPNG 345
                +  TL +  +++SD+G YT+ A N  G
Sbjct: 9676 LVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 9706



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/137 (23%), Positives = 53/137 (38%), Gaps = 5/137 (3%)

Query: 4069  PGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVF--VSLPDAVTVEEGE 4126
             PG++  ++    +K+   + E E   +   E V+ +     P V   V+  D +TV  G+
Sbjct: 11370 PGLIEGNEYRFRIKAANIVGEGEP--RELAESVIAKDILHPPEVELDVTCRDVITVRVGQ 11427

Query: 4127  WARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXX 4185
               R   RV G P+P + W   G  +V   R  L  D       I +  + D GK  +   
Sbjct: 11428 TIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAK 11487

Query: 4186  XXXXXXXXXXXLKVIPR 4202
                        + V+ R
Sbjct: 11488 NSSGHAQGSAIVNVLDR 11504



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 22/71 (30%), Positives = 35/71 (49%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             + VR G+ + + AR  G P P ITW K+G  ++    + +  D     L I  A  +D  
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480

Query: 560   WYQCTAQNVAG 570
              Y  +A+N +G
Sbjct: 11481 KYIISAKNSSG 11491



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 4/60 (6%)

Query: 287   VQLSGNPRPRVTWFKN-GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             V + G P P V W ++ G+ L   +K  I +T ++T L V N  + DSG Y L  EN +G
Sbjct: 15385 VPIKGRPAPEVKWARDHGESL---DKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG 15441



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 8/170 (4%)

Query: 194   QGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE-SITKRYVGE-SDVQ 251
             QGY  E+        +T  T  +  +   ++  +     E +FR  +I K  VGE +DV 
Sbjct: 16373 QGYIVEKC-DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP 16431

Query: 252   ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311
                 ++  L         +  +   ++ G   +  V + G P P V W K    + ++  
Sbjct: 16432 GPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAI 16491

Query: 312   HEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG---CIVTSGYLAVESP 358
              ++  T + T+L + N  + DSG YTL  EN +G     VT   L   SP
Sbjct: 16492 IDV--TSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSP 16539



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 263   VSPPKI---AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             + PP+I   A   +   L+  A  +  V + G P P V W K     I +++ +I  T +
Sbjct: 18605 IEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK--AEGILTDRAQIEVTSS 18662

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
              T L + N  + DSG Y L  EN +G
Sbjct: 18663 FTMLVIDNVTRFDSGRYNLTLENNSG 18688



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 2/79 (2%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
             V +G  I  +  I GKP P  +W K  + I        S T  E  L I EA   D G Y
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTE--LVIKEADRGDSGTY 23708

Query: 4694  KCVAYNSAGRVTVAAKLKV 4712
               V  N  G+  V  K++V
Sbjct: 23709 DLVLENKCGKKAVYIKVRV 23727



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/190 (21%), Positives = 75/190 (39%), Gaps = 11/190 (5%)

Query: 3044  TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
             +G  P      KD+     G+ A     ++  G     I+W+  GK +  S + +     
Sbjct: 24032 SGEAPGIRKEMKDVTT-KLGEAAQLSCQIV--GRPLPDIKWYRFGKELIQSRKYKMSSDG 24088

Query: 3104  GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                 L ++  +  D G Y+C ATN+ G+ E S KL          P+F       E    
Sbjct: 24089 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL-----LLQATPQFHPGYPLKEKYYG 24143

Query: 3164  GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQNHDSGE 3221
                +     V+ +  P   + W+H  + +++S    I+    +  +V+     + H +G+
Sbjct: 24144 AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTH-AGK 24202

Query: 3222  YVCRAYNKYG 3231
             Y  +  N +G
Sbjct: 24203 YKVQLSNVFG 24212



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSL 2833
            F   L ++V  EG    FE ++  S  P  ++ WF + + + + T       FS     L
Sbjct: 8    FTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I    + +SG Y+ KATN  G AT++  L
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 3/91 (3%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS-NDFGFAALDILTVYGED 1913
            K  EGQ+A ++ ++   P P     W+ +G+ + + + ++    + G  +L I+     D
Sbjct: 1421 KCLEGQTARFDLKVVGRPMPE--TFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSD 1478

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            SGE+T  A N  G++  S+ L V++ E  ++
Sbjct: 1479 SGEWTVVAQNRAGRSSISVILTVEAVEHQVK 1509



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 15/157 (9%)

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA 4723
            K   Y ++ R   +  L  ++   E+E   K +A    G++T+       +PD+ +  P+
Sbjct: 1977 KDESYEELLRKTKDELLHWTKELTEEEK--KALA--EEGKITIPT----FKPDKIELSPS 2028

Query: 4724 LTP------LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNA 4776
            +        ++   V +G  A F+ ++  K  P  +W + G  I  +        E N  
Sbjct: 2029 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVC 2088

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             L+I +   ED+ +   +A   AG+  + A L+V++K
Sbjct: 2089 ELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 2244 FVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLD 2303
            FV EL+    V E  +   EC V P    N+  ++YHN   L+S  ++ IT   G  +L 
Sbjct: 2223 FVKELQDI-EVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2278

Query: 2304 IQHCVPEDAGEYS 2316
            ++    ED GEYS
Sbjct: 2279 VKDVTKEDQGEYS 2291



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
            L+++E+ E      E     VS   ++ +WYHN+  LKS  ++T T+  G   L +    
Sbjct: 2227 LQDIEVPESYSGELE---CIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVT 2283

Query: 1644 PEDSGTYT 1651
             ED G Y+
Sbjct: 2284 KEDQGEYS 2291



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 64/331 (19%), Positives = 127/331 (38%), Gaps = 35/331 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            K+    +     FE  +  +  PV  W  K   +   +K+ +    +     L+++ I P
Sbjct: 2756 KDVTALENATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVSERKVH--KLMLQNISP 2812

Query: 139  GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
             D GEYT       G+  C   +  E                   + +E     T  +  
Sbjct: 2813 SDAGEYTAVV----GQLECKAKLFVE-----------TLHITKTMKNIEVPETKTASFEC 2857

Query: 199  EQSR-QTQKVAYTNGTDHSSTDDFKV---DTFEYRLLREVSFRESITKRYVGESDVQIST 254
            E S      +   NG +   ++ FK+         ++   S  +S    +V  +D Q+S 
Sbjct: 2858 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND-QVSA 2916

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
             +      V+P  I    ++   +E     F+V ++        W KNG  + +++K ++
Sbjct: 2917 TLT-----VTPIMITSMLKDINAEEKDTITFEVTVNYEGIS-YKWLKNGVEIKSTDKCQM 2970

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
             T     +L +RN    D+  YT +A    G   ++  L VE+    + +  +   + + 
Sbjct: 2971 RTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHIKDIKVLEK 3026

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTE 405
            ++   E   E+SE  +  Q++K  Q+  +T+
Sbjct: 3027 KRAMFE--CEVSEPDITVQWMKDDQELQITD 3055



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            +K++   E     FE  +     P+M   WLKNG  IE S +F  + +     L +++ +
Sbjct: 2842 MKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2898

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTP 730
             +DS EYT       G  +  A L VTP
Sbjct: 2899 TEDSAEYT----FVCGNDQVSATLTVTP 2922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 3575 AHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
            A F C +   +  ++R +WF  G+ +    +    +      LEI      D G YTCKA
Sbjct: 4354 AKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 4411

Query: 3635 TNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNP 3694
            +N +G  + +  L V    G     +L    K   +    L+  L KR E   E+E    
Sbjct: 4412 SNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPE---EEEPKVE 4468

Query: 3695 PRFTVEIKDNIDVPEGGP 3712
            P+   ++K    VPE  P
Sbjct: 4469 PKKLEKVKKPA-VPEPPP 4485



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/106 (25%), Positives = 46/106 (43%)

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            +G S+    +E   +  P   P I  +  +  + EG      V     P P V+W K+G+
Sbjct: 7869 IGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGK 7928

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
             +  S++  +   H    L V  + ++D+G YT+  EN  G    S
Sbjct: 7929 EVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATAS 7974



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P      H+I  +EG  + +    + V   T  V W  +GK +K   R     +     L
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHL 7947

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            ++      D+G+YT    N+LG A  S  ++VI
Sbjct: 7948 EVPKSVRADAGIYTITLENKLGSATASINVKVI 7980



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/48 (41%), Positives = 29/48 (60%), Gaps = 1/48 (2%)

Query: 486  EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
            + + APK + R S L V+ G+ + L+A   G+P P ITW KD   I+P
Sbjct: 8179 DPIDAPKVILRTS-LEVKRGDEIALDASISGSPYPTITWIKDENVIVP 8225



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/108 (24%), Positives = 42/108 (38%), Gaps = 4/108 (3%)

Query: 56   GDRQPITAGRPGEPSPPIFEQIFKNA-RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE 114
            G+ QP+T   P EP     +   K   +   G   +    + G P P   WT+++    E
Sbjct: 8591 GETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEG---E 8647

Query: 115  CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
             +K  +  +       L+IK     D G Y  TA N  G    +  ++
Sbjct: 8648 LDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVE 8695



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 10/85 (11%)

Query: 503  REGEPVVLNARAVGTPTPRITWQ---------KDGVPIIPNPELRIHTDGGASTLDIPRA 553
            + G  + + A   G PTP+ +W+         KDGV  IP  + ++ T   +S + IP  
Sbjct: 9326 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPE-DAQLETAENSSVIIIPEC 9384

Query: 554  KASDAAWYQCTAQNVAGSTATRARL 578
            K S    Y  TA+N AG      R+
Sbjct: 9385 KRSHTGKYSITAKNKAGQKTANCRV 9409



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 9/97 (9%)

Query: 776  LQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYK-------DGRPITASSRITSIFNFGYV 828
            L++  E++EG N +  A++  V  PT+   W+K       +  P+   + +  +      
Sbjct: 9625 LKEFMEVEEGTNVNIVAKIKGVPFPTLT--WFKAPPKKPDNKEPVLYDTHVNKLVVDDTC 9682

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            +L I   R  D G YT+ AVN LG A     + V  R
Sbjct: 9683 TLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 9719



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 3/73 (4%)

Query: 414   RVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
             R +G+P P+V+WF ++  +  DD  H  +       AL       SDSG    V  N +G
Sbjct: 10344 RYSGKPKPKVSWFKDEADVLEDDRTH--IKTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401

Query: 473   ETAFQCRLNVIEK 485
                  C++NV+++
Sbjct: 10402 SRKGFCQVNVVDR 10414



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/110 (25%), Positives = 44/110 (40%), Gaps = 4/110 (3%)

Query: 378   ETEERIEISEKALAPQF---VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
             +T   IE  EK + P     VK+ +   V  G   RF   + G P P   W  +  +I+ 
Sbjct: 10997 DTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKT 11056

Query: 435   DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
             D  H  +  ++ +  L I N    D+G       N +G       L V++
Sbjct: 11057 D-EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 11105



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 2/76 (2%)

Query: 2926  GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
             GQ + +  +V+ + +PD  I W   GKVL +  R  L  D   V L + +    D G Y 
Sbjct: 11426 GQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 11483

Query: 2986  CKAYNKRGEAFTSSTV 3001
               A N  G A  S+ V
Sbjct: 11484 ISAKNSSGHAQGSAIV 11499



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 2/105 (1%)

Query: 3683  EEITIEDEKPNPPR-FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
             E I  +DE   P       IKD + +  G  +  +  +  +G P  +  W   G+     
Sbjct: 13868 ETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNA-ISILGKPLPKSSWSKAGKDIRPS 13926

Query: 3742  SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
                   +      L I Y   +DAGEYT  ATN +G+     K+T
Sbjct: 13927 DITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVT 13971



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 1735  IPV-GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
             +P+ G PK  + W ++G+P++ + R+          L++K  + +D G Y     N +G+
Sbjct: 16754 VPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 16813

Query: 1794  AVTSSTLFVQSK 1805
                S  +    K
Sbjct: 16814 KTASIEIVTLDK 16825



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P  +  F       G + K E  + G P P +SW +   PL +  + ++   E+T   ++
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV---EETATSTV 17871

Query: 132   L-IKQIGPGDEGEYTCTARNQYGEA 155
             L IK+    D G+YT TA N  G A
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTA 17896



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/113 (21%), Positives = 46/113 (40%)

Query: 4391  EHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP 4450
             E    T   +V+  V+P +  +  K      V   E  +   +  G PLP+I W ++   
Sbjct: 19273 EPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIE 19332

Query: 4451  IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
             I+     +I +    ++L ++     D+  +    +N  GT   + N  V +K
Sbjct: 19333 IEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 4525  VTSGQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
             V +G++++++  + G +P+ V  W K+G +++   R +I+  D    L + +   +D+G+
Sbjct: 19304 VKAGEVLKINADIAG-RPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQ 19362

Query: 4584  YECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             Y     N AG       C V      DKP P
Sbjct: 19363 YVLTLKNVAGTRSVAVNCKV-----LDKPGP 19388



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTLRVRNTQ-KSDSGHYT 337
             G+  +  V   G P P +TWF +GQ+L+ NS    I  T ++T L ++N Q K+ +G Y 
Sbjct: 24146 GSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYK 24204

Query: 338   LLAENPNGCI 347
             +   N  G +
Sbjct: 24205 VQLSNVFGTV 24214



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/164 (24%), Positives = 67/164 (40%), Gaps = 10/164 (6%)

Query: 3075  TGDQSMVIEWFYNGKTIEA---SHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
             TG    +++W+  GK I A    +RI+  +  G   L I      D+  Y  RATN+ G 
Sbjct: 24455 TGHPKPIVKWYRQGKEIIADGLKYRIQE-FKGGYHQLIIASVTDDDATVYQVRATNQGGS 24513

Query: 3132  AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD-DPDMKIEWYHNGQ 3190
                +  LE    +K   P+    +  +  L+ G+    +   +P    PD  I W     
Sbjct: 24514 VSGTASLEVEVPAKIHLPKTLEGMGAVHALR-GEVVSIK---IPFSGKPDPVITWQKGQD 24569

Query: 3191  PMRHSTRIKTVSDFGFVVLDIAY-TQNHDSGEYVCRAYNKYGED 3233
              + ++   + +    F  L      +  D+G YV  A N++G D
Sbjct: 24570 LIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGID 24613



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 391   APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHA 449
             AP+     +   V  G+ TRF   V  +P  EV W+ N  ++++  + KI   N SG   
Sbjct: 25876 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQE--SSKIHYTNTSGVLT 25933

Query: 450   LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             L I +    DSG    V  N  GE +    L+V
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 4622  PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYT 4679
             PP+I     D  + EG+ +  +C   G+P P V W  G + I   +   F +  T D  T
Sbjct: 26831 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 26890

Query: 4680  LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             L I +   +D G Y     N  G  +    + +
Sbjct: 26891 LIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 10/120 (8%)

Query: 3943 LTQMEATIKKYTSEVYLTEDD----LYDVDKKQPPR--FVTQIQSQTSLVEMETTKFECQ 3996
            + ++E  I K T E  L ED       D+ + +     F  +I++   L  M  T F C+
Sbjct: 1209 IKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVT-FHCK 1267

Query: 3997 LAPVGDPNMKVEWFFNGKPLLHKNRF-TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            ++  G P  K+ W+ +GK + H  R+       G  ++    V PED G Y   A+N+ G
Sbjct: 1268 MS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1325



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 8/126 (6%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            FT  L ++    +   A FE     T +P +KV+WY +G  +  G ++R   D     L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK-RNIILESQ---LPKGMEGTIDKIAA 3537
            I      D+ +Y C    +     TTA + V+G     + E Q   +P+   G ++ I +
Sbjct: 2187 ILTIDTSDAEDYSCVLVED-ENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVS 2245

Query: 3538 LEGYSG 3543
             E   G
Sbjct: 2246 PENIEG 2251



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 7/89 (7%)

Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIAS 1107
            PLK  N ++EG  A  E +V    D+T +V+WY N +QI   +R+Q         L I  
Sbjct: 2404 PLKDVN-VIEGTKAVLECKVSVP-DVT-SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINR 2460

Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
              A D G Y ++     G  + + +++VE
Sbjct: 2461 THASDEGPYKLI----VGRVETNCNLSVE 2485



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/179 (22%), Positives = 67/179 (37%), Gaps = 13/179 (7%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D +V EG     +C+V+      V W++ND QI+ D   + +V +     L+I     S
Sbjct: 2406 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV-KGTKQRLVINRTHAS 2464

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D G    +     G     C L+V   E++   K +     L   E + VV       + 
Sbjct: 2465 DEGPYKLIV----GRVETNCNLSV---EKI---KIIRGLRDLTCTETQNVVFEVELSHSG 2514

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA-QNVAGSTATRA 576
               + W      I P+ + +I   G    L +      D   Y   A +N+     T A
Sbjct: 2515 ID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVA 2572



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 44/206 (21%), Positives = 75/206 (36%), Gaps = 16/206 (7%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            D   +Y    + R++  R+ + E  +  + ++  QD     G    F   +  +   EV 
Sbjct: 6390 DDECEYACGVEDRKSRARLFVEE--IPVEIIRPPQDILEAPGADVVFLAELN-KDKVEVQ 6446

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
            W  N+  +     H+++ +E   H L I ++   D G    +A++K              
Sbjct: 6447 WLRNNMVVVQGDKHQMM-SEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKL-------- 6497

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
             E   APK       L V  G+P+ +       P     W K+  P+       I T   
Sbjct: 6498 -ELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAE 6553

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
             ++  I  AK  D   Y+   QN  G
Sbjct: 6554 QTSFRILEAKKGDKGRYKIVLQNKHG 6579



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 5/112 (4%)

Query: 377  RETEERIEISEKALAPQF---VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR 433
            R TEE I+  +   AP+    VK+     V  G        VTG+P P++TW   D  ++
Sbjct: 7177 RPTEE-IQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7235

Query: 434  DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             D     + N      + I +   SD+G     A N  G       +NV++K
Sbjct: 7236 QD-KRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7286



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 289   LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +SG P P VTW  N + L    +  I TT   +++ ++N Q+S  G Y+LLA+N  G
Sbjct: 10051 VSGKPPPTVTWNMNERTL--PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 10105



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 6/137 (4%)

Query: 2606  IIDQAMRPESWE-QIQLK----EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHV 2660
             ++D+ +  + +E ++Q K    E+   K  E+ V   +Q+ P+    L     +  G  +
Sbjct: 11664 MVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQK-PVLDLKLSGVLTVKAGDTI 11722

Query: 2661  YLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKAT 2720
              LEA V  +  P +     K+   LT   R+K          S+   +  D G Y   AT
Sbjct: 11723 RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTAT 11782

Query: 2721  NLLGEAVSTASIKIEDR 2737
             N  G  V+ A++ + D+
Sbjct: 11783 NTAGSFVAYATVNVLDK 11799



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 7/98 (7%)

Query: 380   EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
             EE++E  +  L  +  K+    ++  G   R    + GRP PEV W   D +IRD     
Sbjct: 16437 EEKLEAPDIDLDLELRKII---NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRD---AA 16490

Query: 440   ILVNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAF 476
             I+   S   +L++ NV   DSG  T    N SG ++AF
Sbjct: 16491 IIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAF 16528



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 17/130 (13%)

Query: 637   PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-FGYIS 695
             P F   L +    EG  + FE R+  +  PT+K  W K+GQ +        I     Y +
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYA 25355

Query: 696   LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
             L +     +D+G Y   A +  G    +A L V             E L+Y +Q E  SK
Sbjct: 25356 LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV-------------ERLRYKKQ-EFKSK 25401

Query: 756   YQHQESIEEQ 765
              +H+  +++Q
Sbjct: 25402 EEHERHVQKQ 25411



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 20/69 (28%), Positives = 31/69 (44%)

Query: 1201  LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
             L     PT  V+W+HNG  +   S+       G + L+I+   + D+G Y     N+ G 
Sbjct: 25898 LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 25957

Query: 1261  AHTSAIVRV 1269
             A   A + V
Sbjct: 25958 ASDYATLDV 25966



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 9/149 (6%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G + +   L  +AE+  PP F      + + + S    + R+  +   +  V+++ +G  
Sbjct: 87   GQATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAE 143

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            + +    +   +     L I   Y  D+G Y+  ATN  G AT + +L V+G      E 
Sbjct: 144  IQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EE 197

Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIE 3688
            ++P+       S  ++ E+   R E  IE
Sbjct: 198  EVPAKKTKTIVSTAQISESRQTRIEKKIE 226



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/109 (22%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V   T  P F   ++  +++++G     + R+   G  T  V++ +DG  +++S      
Sbjct: 97   VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQIS 153

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                  +L I      D+G Y+  A N++G+AT++A L +  ++++ A+
Sbjct: 154  QEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+S   + +G  V L+ +V     P +K  ++++G  + +    + + +  L +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L I     +DSG Y+  ATN +G A STA + ++
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 8/112 (7%)

Query: 1042 KPRFLG---PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            KPR +G   PLK    +  G++A F+  +  +    + VEWY  GK++  ++++    + 
Sbjct: 5695 KPRVIGLLRPLKDVT-VTAGETATFDCELSYED---IPVEWYLKGKKLEPSDKVVPRSEG 5750

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSA-SMTVETRSSIDTSSIHRG 1149
                L +  V+ ED+G   + A++    A L      VE    ++  ++  G
Sbjct: 5751 KVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEG 5802



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 19/65 (29%), Positives = 32/65 (49%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P  T+ W  +G++++A  R    +D     L++  +   D+G Y     NKLG A  +  
Sbjct: 7917 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 7976

Query: 2199 LKVAG 2203
            +KV G
Sbjct: 7977 VKVIG 7981



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             GQ + + A+V+ R +P+  I W K G  L    R+    D   V L I      D G Y 
Sbjct: 11426 GQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 11483

Query: 2717  CKATNLLGEAVSTASIKIEDR 2737
               A N  G A  +A + + DR
Sbjct: 11484 ISAKNSSGHAQGSAIVNVLDR 11504



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 4/122 (3%)

Query: 4091  EASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWL--LNG 4148
             E+ W  T E VV+E   + P + + L   +TV+ G+  R    V G P P V W    + 
Sbjct: 11686 ESDWVKTEEVVVKEDLQK-PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDA 11744

Query: 4149  NTIVNGSRYKL-TYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR 4207
               +    R K+ T      F + K ++ D GK  V              + V+ +    R
Sbjct: 11745 TDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVR 11804

Query: 4208  GV 4209
              +
Sbjct: 11805 NL 11806



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 31/149 (20%), Positives = 66/149 (44%), Gaps = 9/149 (6%)

Query: 631   DRVYPPPQFIVPLKSVTAMEGG-KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
             + V P     V +KS+  ++ G  +  +  +   G P   + W K+G  ++ +       
Sbjct: 12792 ENVPPRIDLSVAMKSLLTVKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAM 12849

Query: 690   RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT----PRATIERTSQHPE--T 743
             +    +L++ S+N +DSG+YT  A +++G       L V     P A+++    + +   
Sbjct: 12850 QRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAM 12909

Query: 744   LQYIQQLEDYSKYQHQESIEEQTSQRPQF 772
             L +   LED         ++++ + RP +
Sbjct: 12910 LSWEPPLEDGGSEITNYIVDKRETSRPNW 12938



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/99 (22%), Positives = 43/99 (43%), Gaps = 4/99 (4%)

Query: 3047  PP--EFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
             PP  + +   K ++ +  G     +A++   G     + W  +G  ++ +  I+      
Sbjct: 12795 PPRIDLSVAMKSLLTVKAGTNVCLDATVF--GKPMPTVSWKKDGTLLKPAEGIKMAMQRN 12852

Query: 3105  MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
             +  LE+      DSG Y+  A N  G    ++KL+ +DK
Sbjct: 12853 LCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 1/93 (1%)

Query: 773   IRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNI 832
             ++ L DL  L +  N++F  ++     P   V W K   P+   +R++   +    +L +
Sbjct: 13487 LKGLPDLCYLAK-ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIV 13545

Query: 833   MHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
                +  DAG YT+   N  G    T SI+V  +
Sbjct: 13546 YDCQKSDAGKYTITLKNVAGTKEGTISIKVVGK 13578



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 7/102 (6%)

Query: 472   GETAFQCRLNVIEKEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
             GE A    + ++E+E  +AP F    E   TL VR G  + +     G P P +TW KD 
Sbjct: 14260 GEPAVIPDVEIVERE--MAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN 14317

Query: 529   VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             + +       I      + L IP     D   +  T +N AG
Sbjct: 14318 INL--KNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 14357



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/156 (23%), Positives = 68/156 (43%), Gaps = 13/156 (8%)

Query: 4548  LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             L NG+ ++ +  N ILE + T + L  +A    + ++  +A N+AG     +E   ++  
Sbjct: 14901 LPNGRWLKANFSN-ILENEFTVSGLTEDA----AYEFRVIAKNAAGAISPPSEPSDAITC 14955

Query: 4608  TKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
               D   P+ K       +    KD ++ + G+A      + G+P PT++W K  K ++ +
Sbjct: 14956 RDDVEAPKIK-------VDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGT 15008

Query: 4667  KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                ++        L   ++   D G Y   A N  G
Sbjct: 15009 AKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15044



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 50/195 (25%), Positives = 81/195 (41%), Gaps = 17/195 (8%)

Query: 3042  DDTGRPPEFTTV-FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
             DD   P     V FKD V +  G+    EA +  +G     +EW  +GK +E + ++   
Sbjct: 14957 DDVEAPKIKVDVKFKDTVILKAGEAFRLEADV--SGRPPPTMEWSKDGKELEGTAKLEIK 15014

Query: 3101  YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK-SKGQKPRFTTHIQNIE 3159
              A     L    +   DSG Y+  ATN  G A+    ++ +D+    + P   T + + +
Sbjct: 15015 IADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 15074

Query: 3160  GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV-VLDIAYTQNHD 3218
              +             P+DD   KI+  H     R ++R+   +    V V  +  T+   
Sbjct: 15075 CVLS--------WFPPLDDGGAKID--HYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124

Query: 3219  SGEYVCR--AYNKYG 3231
               EY+ R  A NKYG
Sbjct: 15125 GNEYIFRVMAVNKYG 15139



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 1459  GQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGI 1516
             G+     C++   P+ D    ++W++ G+ +    +++   D     L ++    ED G+
Sbjct: 24050 GEAAQLSCQIVGRPLPD----IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 24105

Query: 1517  YTCRAVNLVGTDEVSCRLTCRST 1539
             YTC A N VG  E S +L  ++T
Sbjct: 24106 YTCIATNEVGEVETSSKLLLQAT 24128



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/101 (23%), Positives = 42/101 (41%), Gaps = 2/101 (1%)

Query: 1302  REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
             ++  T+  AP+ +  + +     G N      +Q     T  V+W+ NG  ++   +   
Sbjct: 25868 QQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHY 25925

Query: 1362  AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                   + L++L  + +DSG Y    TN  GEA     L V
Sbjct: 25926 TNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 17/54 (31%), Positives = 30/54 (55%)

Query: 2406  PTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             PT +V+W+ N   +++SS+I  T+  G +++ I     +D G Y    +N  GE
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 25957



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/92 (28%), Positives = 42/92 (45%)

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            +GE   +++T    +   V   KI +  +N  + E  DA F V+L+      V W KNG 
Sbjct: 2640 IGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV 2699

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L ++ K+ I       +LR++N    D   Y
Sbjct: 2700 VLESNEKYAISVKGTIYSLRIKNCAIVDESVY 2731



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KDI+V E + A FE     V +P + V+W+++   ++ ++R+    +     L +
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLI 3070

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                  D+G YT  A    G  V+++ LFV+ +
Sbjct: 3071 PSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3099



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 56/262 (21%), Positives = 107/262 (40%), Gaps = 18/262 (6%)

Query: 1410 LESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLE 1469
            +ES++    E++ Y    SR K  D    +  +    V+  K  E++   +    E   E
Sbjct: 4161 VESKYLISPEEVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLKPSEEKE-ESSSE 4219

Query: 1470 PVTD--SNLKVEWFKNGQPVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVN--- 1523
              T+  + +K++  + G     G     P+ D      DI+ L    + I   + VN   
Sbjct: 4220 SGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLT---TSITNAKEVNWYF 4276

Query: 1524 ---LVGTDEVSCRLTCRSTTDIVR---STQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
               LV +DE    L  ++T  +V    +T++  G    + L D  K   +  +  V   A
Sbjct: 4277 ENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 4336

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P+    ++ +E+  G  A F   +   S   ++ +W+   + +    + +  ++    +L
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSL 4394

Query: 1638 DIMSCLPEDSGTYTCRAINALG 1659
            +I+     D G YTC+A N  G
Sbjct: 4395 EILRTQVVDCGEYTCKASNEYG 4416



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 5/89 (5%)

Query: 4727 LRDIVVYE----GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782
            ++DI++ E    G  A F+  ++     T  W+++G+ I E+P  + I +G +  L I +
Sbjct: 4624 IKDIILTESEFVGSSAIFECLVSPSTAITT-WMKDGSNIRESPKHRFIADGKDRKLHIID 4682

Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                D G +TC       +  ++AKLVV+
Sbjct: 4683 VQLSDAGEYTCVLRLGNKEKTSTAKLVVE 4711



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 40/181 (22%), Positives = 75/181 (41%), Gaps = 18/181 (9%)

Query: 3047 PP--EFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            PP  EF     D+  + E ++A +E  L     ++  ++WF +G  I+   +   +    
Sbjct: 5874 PPHVEFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGA 5929

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            + +L I      D   YSC          ++V LE       ++  FT ++ NIE + + 
Sbjct: 5930 VRILVINKCLLDDEAEYSCEVRTARTSGMLTV-LE-------EEAVFTKNLANIE-VSET 5980

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
             +    C V     P  ++ WY   + +  + R + +++    +L I      D+G Y C
Sbjct: 5981 DTIKLVCEV---SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 6037

Query: 3225 R 3225
            R
Sbjct: 6038 R 6038



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/102 (33%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 4079 KHMKSIEKIR-EMEASWQVTPEQ---VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRV 4134
            KHM +I+      E  + VT  Q   V E      P  FV   +  TV E + A F C++
Sbjct: 6290 KHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQL 6349

Query: 4135 TGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYD 4176
            +   K  V W  NG  I  G +YK   DG  H  I K  + D
Sbjct: 6350 S-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 6390



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            PKI    ++  +  G      V     P+    WFK  + L  S K  I TT   T+ R+
Sbjct: 6503 PKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPL--STK-TIDTTAEQTSFRI 6559

Query: 326  RNTQKSDSGHYTLLAENPNG 345
               +K D G Y ++ +N +G
Sbjct: 6560 LEAKKGDKGRYKIVLQNKHG 6579



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 10/100 (10%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF--------INDRQIRDDYNHKILVN 443
            P  + + +  +V EG       ++ G P+P +TWF          +  + D + +K++V+
Sbjct: 9620 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 9679

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            ++    L+I     SD+G+ T  A N  G  + + RLNV+
Sbjct: 9680 DT--CTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVL 9717



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 501   NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             +++ G+ + L+A   G P P++TW+K+     P  + RI      S L+I  A   D   
Sbjct: 10732 HIKVGDTLRLSAIIKGVPFPKVTWKKEDRD-APT-KARIDVTPVGSKLEIRNAAHEDGGI 10789

Query: 561   YQCTAQNVAGSTATRARL 578
             Y  T +N AGS     ++
Sbjct: 10790 YSLTVENPAGSKTVSVKV 10807



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 6/119 (5%)

Query: 371   ITDTQQRETEERIEISEKALAPQFVKV---CQDR-DVTEGKMTRFDCRVTGRPYPEVTWF 426
             + + + RE  E + I++  L P  V++   C+D   V  G+  R   RV GRP P++TW 
Sbjct: 11388 VGEGEPRELAESV-IAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITW- 11445

Query: 427   INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
               + ++        L+ +     L I     +D G     A+N SG       +NV+++
Sbjct: 11446 TKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDR 11504



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 286   QVQLSGNPRPRVTWFKNGQRLINSN-KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPN 344
             +  + G P P V W K+G+ L  +  + EI +T   TTL V++  ++D G Y L   N  
Sbjct: 18231 EADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVG 18290

Query: 345   G 345
             G
Sbjct: 18291 G 18291



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 17/77 (22%), Positives = 35/77 (45%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  R +    G P+P + W+++   I+   + +I      + L +R    +   V+   A
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 21536

Query: 4486  ENRGGTAKCSANLVVEE 4502
             +N  G+AK    + V++
Sbjct: 21537 KNASGSAKAEIKVKVQD 21553



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/74 (28%), Positives = 35/74 (47%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             + +R G  +VL+A   G P P+I W K    +    ++ +   G  +T  I     SD+ 
Sbjct: 22560 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22619

Query: 560   WYQCTAQNVAGSTA 573
              Y  T +N +G+ A
Sbjct: 22620 KYTLTVKNASGTKA 22633



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 40/159 (25%), Positives = 56/159 (35%), Gaps = 5/159 (3%)

Query: 3629  LYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE 3688
             L  CKA        V+ K  V       L       F+   ++ + + E       +T++
Sbjct: 23174 LEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQ 23233

Query: 3689  DEKPNPP-RFTVEIKDNIDVPEGGPVHFDCRVEPV-GDPTMRIDWFHNGRPFATGSRVHT 3746
             D +  P    +   +  I VP G PV     V P+ G P     WF  G       RV  
Sbjct: 23234 DLRVLPTIDLSTMPQKTIHVPAGRPVEL---VIPIAGRPPPAASWFFAGSKLRESERVTV 23290

Query: 3747  LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                     L I     RD GEYT    N  G+ + T K+
Sbjct: 23291 ETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23329



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 3/95 (3%)

Query: 3695  PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
             P    E+KD +    G      C++  VG P   I W+  G+      +    +D     
Sbjct: 24036 PGIRKEMKD-VTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT 24092

Query: 3755  LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
             L +      D G YTC ATN+ G   T++K+   A
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/147 (19%), Positives = 60/147 (40%), Gaps = 8/147 (5%)

Query: 1794  AVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGP 1853
             ++++ ++    ++ +++ S     +  + QLE S+       ++  +   P  I  L   
Sbjct: 26785 SMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM----LKAGIRGIPPKIEALPSD 26840

Query: 1854  TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH--RYRTSNDFGFAALDILTVYG 1911
               + EG+     C     P P   V W   G+ + S    R+   N      L I+ V  
Sbjct: 26841 ISIDEGKVLTVACAFTGEPTPE--VTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQK 26898

Query: 1912  EDSGEYTCKAINNLGQAVSSIRLNVQS 1938
             +D G YT    N  G   +++ ++++S
Sbjct: 26899 QDGGLYTLSLGNEFGSDSATVNIHIRS 26925



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 19/163 (11%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSG 3119
            +E Q   +E  L  +G   + + W +  K I+ S + + + A G +  L +L     D G
Sbjct: 2499 TETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEG 2554

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             Y+  A       +++V    + K    +            + + Q A FEC V    +P
Sbjct: 2555 KYTFYAGENITSGKLTVAGGAISKPLTDQT-----------VAESQEAVFECEVA---NP 2600

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            D K EW  +G+ +  +  I++ SD     L IA T+  D GEY
Sbjct: 2601 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY 2643



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 8/94 (8%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            F  H+K   K++E +    E +V   ++P++ ++W K+   L    R+K   +  +  L 
Sbjct: 3014 FRKHIKDI-KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLL 3069

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            I S R  D+G YT  A    G  VSTA + +E R
Sbjct: 3070 IPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3099



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            K++E + A FE  V   S+  +TV+W  + +++   +RI+   +     L I S R  D+
Sbjct: 3022 KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078

Query: 1114 GVYTVVARNAAGEAQL 1129
            G YTVVA      A+L
Sbjct: 3079 GKYTVVAGGNVSTAKL 3094



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAED-SGVYTVVARNAAGEAQLSASMTV 1135
            V WYF  K + S  + +   D     L I  V  ED  G Y   A N +G+   SA +TV
Sbjct: 4272 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331

Query: 1136 ETRSS 1140
              R++
Sbjct: 4332 VKRAA 4336



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/68 (29%), Positives = 34/68 (50%)

Query: 2667 EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            E ++ PN++ +WFK G  +    +        + +L I   +  D G YTCKA+N  G  
Sbjct: 4359 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 4418

Query: 2727 VSTASIKI 2734
              TA++ +
Sbjct: 4419 SCTATLTV 4426



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 9/126 (7%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G SA +EC + P         W  +G  ++   ++R   D     L I+ V   D+GEYT
Sbjct: 4636 GSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 4692

Query: 1919 CKAINNLGQAVSSIRLNVQS-KESIIRDSQHESALEKIQ--YLEDDSRYKRAV---QDDS 1972
            C       +  S+ +L V+      ++  + E  + K Q  YL  +   +R V   +D  
Sbjct: 4693 CVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGK 4752

Query: 1973 FVVEKP 1978
             VVEKP
Sbjct: 4753 IVVEKP 4758



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 8/122 (6%)

Query: 2336 AKGSIISESQRPEGLEKIRELE-SAEPFKRPEIPEPVTRQRPV-FTQPLQNIDNIQEGQT 2393
            ++G + + + R   LE   E++ +A+ FK         ++ PV FT+PL++   ++EG T
Sbjct: 5748 SEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHA--NLFVKEPPVEFTKPLED-QTVEEGAT 5804

Query: 2394 AHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453
            A  +C    V     KV+WF+N   I  S +     D     + I     ED   Y C A
Sbjct: 5805 AVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861

Query: 2454 SN 2455
             +
Sbjct: 5862 KD 5863



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 61/307 (19%), Positives = 115/307 (37%), Gaps = 47/307 (15%)

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
            ++++++E  +  F  +++     +  WF+N + + +S+K+ I+      TLR+R+    D
Sbjct: 6150 KDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDD 6208

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
              +Y +   N  G         V+S     V+++  + +   +  ET E+          
Sbjct: 6209 QANYNVSLTNHRG-------ENVKSAANLIVEEEDLRIVEPLKDIETMEK---------- 6251

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
                          K   F C+V  R    + W  N  ++  D      V++   H L I
Sbjct: 6252 --------------KSVTFWCKV-NRLNVTLKWTKNGEEVPFDNRVSYRVDKY-KHMLTI 6295

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             +    D G     A    G+      L +IE       +FVE      V E +  V + 
Sbjct: 6296 KDCGFPDEGEYIVTA----GQDKSVAELLIIE----APTEFVEHLEDQTVTEFDDAVFSC 6347

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            + +      + W ++G  I    + +   DG    L I   +  D   Y C  ++     
Sbjct: 6348 Q-LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVED----R 6402

Query: 573  ATRARLY 579
             +RARL+
Sbjct: 6403 KSRARLF 6409



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 2/79 (2%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG+           P P   V W+ +GK +++  R    ND   A L++      D+G Y
Sbjct: 7903 EGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 7960

Query: 1918 TCKAINNLGQAVSSIRLNV 1936
            T    N LG A +SI + V
Sbjct: 7961 TITLENKLGSATASINVKV 7979



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/131 (23%), Positives = 52/131 (39%), Gaps = 5/131 (3%)

Query: 3657  LEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRF--TVEIKDNIDVPEGGPVH 3714
             LE +    F++   +   +       + +TI  E   PPR   +V +K  + V  G  V 
Sbjct: 12759 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-PPRIDLSVAMKSLLTVKAGTNVC 12817

Query: 3715  FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
              D  V   G P   + W  +G        +          L++  +  +D+G+YT  A N
Sbjct: 12818 LDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 12875

Query: 3775  KWGSATTTAKI 3785
               GS + T K+
Sbjct: 12876 SSGSKSATIKL 12886



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/84 (23%), Positives = 36/84 (42%)

Query: 4730  IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
             + V  G        +  K  PT+ W ++G L+      +M  + N   L + +   +D+G
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12867

Query: 4790  TFTCRATTAAGQVETSAKLVVKSK 4813
              +T  A  ++G    + KL V  K
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDK 12891



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 17/71 (23%), Positives = 33/71 (46%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             +  + G P  ++    G P P++TW+ + + +     + I T    +TL +  +   D+ 
Sbjct: 22160 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22219

Query: 560   WYQCTAQNVAG 570
              Y  T +N AG
Sbjct: 22220 RYFLTLENTAG 22230



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/79 (26%), Positives = 32/79 (40%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
             +  G  +     + GKP P + W KGDK +   +   +  T    T  I      D G Y
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKY 22621

Query: 4694  KCVAYNSAGRVTVAAKLKV 4712
                  N++G   V+  +KV
Sbjct: 22622 TLTVKNASGTKAVSVMVKV 22640



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 8/116 (6%)

Query: 48    MTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR 107
             M+   ES  + +P+   R   P   + + + K      G + +    + G P PV++W++
Sbjct: 22928 MSEYSESIAEIEPVE--RIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK 22985

Query: 108   KKAPLVECNKYSMRYNEQTGDVSLLI-KQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
             +   L      S    + T   SLLI  ++   D G+YT  A NQ G+   +V ++
Sbjct: 22986 QGIDLA-----SRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23036



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 15/42 (35%), Positives = 21/42 (50%)

Query: 4110  PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
             PP   +LP  ++++EG+     C  TG P P V W   G  I
Sbjct: 26831 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 26872



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 16/179 (8%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  P   T++ KDI +  E     +E ++   G   +  +W  NG  I+++ + +     
Sbjct: 2919 TVTPIMITSMLKDI-NAEEKDTITFEVTVNYEG---ISYKWLKNGVEIKSTDKCQMRTKK 2974

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L I      D+  Y+  A      A + V+   ++        F  HI++I+ L+ 
Sbjct: 2975 LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIE--------FRKHIKDIKVLEK 3026

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             + A FEC V    +PD+ ++W  + Q ++ + RIK   +     L I  T+  D+G+Y
Sbjct: 3027 -KRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKY 3081



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/137 (21%), Positives = 59/137 (43%), Gaps = 10/137 (7%)

Query: 1270 IERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVH 1329
            ++ S+   ++ +E   E++  ++        ++ED  ++  P     L +  + EG  VH
Sbjct: 4207 LKPSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTP-----LVDTVSEEGDIVH 4261

Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED-SGVYTCQAT 1388
            L   +         V W+   K + +  +F+   + +   L +  V  ED  G Y C+A 
Sbjct: 4262 LTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 4317

Query: 1389 NQLGEAVTSCALRVIAK 1405
            N  G+  TS  L V+ +
Sbjct: 4318 NDSGKTATSAKLTVVKR 4334



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 7/140 (5%)

Query: 3662 PSHFKSGTESIQKLEETLH-KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVE 3720
            PS  K  + S    EE    K +E      K + P     + D +   EG  VH    + 
Sbjct: 4209 PSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVS-EEGDIVHLTTSIT 4267

Query: 3721 PVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD-AGEYTCRATNKWGSA 3779
               +    ++W+   +   +  +   L D     L ID +   D  GEY C A N  G  
Sbjct: 4268 NAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKT 4323

Query: 3780 TTTAKITCSAKRDIVLESQL 3799
             T+AK+T   +   V++ ++
Sbjct: 4324 ATSAKLTVVKRAAPVIKRKI 4343



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 18/78 (23%), Positives = 41/78 (52%), Gaps = 1/78 (1%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P +I + P++     GAD  F  +L+ + +  V W +N   ++  +KH++++      L+
Sbjct: 6414 PVEIIRPPQDILEAPGADVVFLAELNKD-KVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQ 6472

Query: 325  VRNTQKSDSGHYTLLAEN 342
            + + +  D G Y  +A++
Sbjct: 6473 ICDIKPRDQGEYRFIAKD 6490



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 3/91 (3%)

Query: 2645 TTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            T  L+++D +V EG+   L   V  R  P   + W K+G  +    RL    D     L 
Sbjct: 7891 TIDLETHDIIVIEGEK--LSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLE 7948

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +      D+GIYT    N LG A ++ ++K+
Sbjct: 7949 VPKSVRADAGIYTITLENKLGSATASINVKV 7979



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 7/95 (7%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK-------DGVPIIPNPELRIHTDG 543
            P  ++    + V EG  V + A+  G P P +TW K       +  P++ +  +      
Sbjct: 9620 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 9679

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               TL IP+++ SD   Y  TA N  G+ +   RL
Sbjct: 9680 DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9714



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/84 (26%), Positives = 36/84 (42%)

Query: 4727  LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
             +  +VV  G   +F   I     PT +W  +G+ I     + +  +  ++VL I N    
Sbjct: 11020 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11079

Query: 4787  DTGTFTCRATTAAGQVETSAKLVV 4810
             DTG +    + AAG    +  L V
Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 2/86 (2%)

Query: 3840  TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899
             TV   + +R   RV+ + +P   I W + GK+L    R   + D+  V L I      D 
Sbjct: 11422 TVRVGQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADH 11479

Query: 3900  GEYICRAVNDFGEDFTKATISCKKLP 3925
             G+YI  A N  G     A ++    P
Sbjct: 11480 GKYIISAKNSSGHAQGSAIVNVLDRP 11505



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 502   VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
             VR G P+ L A   G P P++TW+K G+  +   + ++      + L IP +   D+  Y
Sbjct: 12121 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVR-KGQVDLVDTMAFLVIPNSTRDDSGKY 12179

Query: 562   QCTAQNVAGSTA 573
               T  N AG  A
Sbjct: 12180 SLTLVNPAGEKA 12191



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 2/87 (2%)

Query: 776   LQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHL 835
             ++ L  ++ G N   +A  T    P   V W KDG  +  +  I         +L +  +
Sbjct: 12804 MKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSV 12861

Query: 836   RAEDAGSYTVRAVNKLGEAISTASIRV 862
               +D+G YT+ A N  G   +T  ++V
Sbjct: 12862 NRKDSGDYTITAENSSGSKSATIKLKV 12888



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/69 (30%), Positives = 34/69 (49%)

Query: 4525  VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
             V +G+  RL+  V G     + WL+  K+++   R +I   D    L++ +A   D G+Y
Sbjct: 17140 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17199

Query: 4585  ECVAINSAG 4593
                A N AG
Sbjct: 17200 ILRASNVAG 17208



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 35/127 (27%), Positives = 50/127 (39%), Gaps = 8/127 (6%)

Query: 2629  VPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
             VP +  D  +Q  P       +Y  +  G+ + +E  V  R  PN  I W K+G  L   
Sbjct: 17804 VPVIAKDLTIQ--PSLKLPFNTYS-IQAGEDLKIEIPVIGRPRPN--ISWVKDGEPLKQT 17858

Query: 2689  ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPD 2748
              R+          L I     DD G YT  ATN  G A    S+ + ++    G  + P 
Sbjct: 17859 TRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKP---GPPVGPV 17915

Query: 2749  SLDRIGA 2755
               D + A
Sbjct: 17916 RFDEVSA 17922



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 2/98 (2%)

Query: 1977  KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
             +P    P     +  G  + +E  +  +  P   + W  +G P++Q  R           
Sbjct: 17814 QPSLKLPFNTYSIQAGEDLKIEIPV--IGRPRPNISWVKDGEPLKQTTRVNVEETATSTV 17871

Query: 2037  LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074
             L I     +D G Y   ATN+ G A    SV V  K G
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG 17909



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 5/98 (5%)

Query: 68    EPSPPIFE---QIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
             E  PPI E   + F       G + + +  ++G P P V+W +    + +  + +M   +
Sbjct: 21455 ENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK--RMNMEITD 21512

Query: 125   QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
               G  SL ++       G YT  A+N  G A   + ++
Sbjct: 21513 VLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 21550



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 2/107 (1%)

Query: 59    QPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNK 117
             +PIT         P F++  +N       NA    K+ G+P P+V W R+ K  + +  K
Sbjct: 24418 EPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 24477

Query: 118   YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
             Y ++   + G   L+I  +   D   Y   A NQ G    +  ++ E
Sbjct: 24478 YRIQ-EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRG-NPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
             P+  QI  +A   +GG+ K+  K+   + +  V+W      L    KY + Y +  G   
Sbjct: 25072 PVSGQIM-HAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED--GVAI 25128

Query: 131   LLIKQIGPGDEGEYTCTARNQYGE 154
             L +K I   D+G Y C   N YGE
Sbjct: 25129 LYVKDITKLDDGTYRCKVVNDYGE 25152



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 489   VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG--GAS 546
             + PK     S +++ EG+ + +     G PTP +TW   G  I    + R H +     +
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 26889

Query: 547   TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             TL I   +  D   Y  +  N  GS +    ++
Sbjct: 26890 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIH 26922



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 4512  VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
             +PP       ++++  G+++ +    TG    +V W   G+K+  Q   R  I   D   
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 26889

Query: 4570  TLLILEAYPQDSGKYECVAINSAG 4593
             TL+I++   QD G Y     N  G
Sbjct: 26890 TLIIMDVQKQDGGLYTLSLGNEFG 26913



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 6/113 (5%)

Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALD 3756
            FT E++D +   +     F+C      +P +++ W+ +G     G +    +D     L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ---LPQGMSGE 3806
            I  I   DA +Y+C         TT   I   A  + V E Q   +P+  SGE
Sbjct: 2187 ILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGE 2239



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 2776 FISHLNNIVCKEGDNIH-FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            F   L ++V KE D +  FEC      +P +K++W+ +   +  G +Y+   D     L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTS 2860
            I      D+  Y+C     +   TT+
Sbjct: 2187 ILTIDTSDAEDYSCVLVEDENVKTTA 2212



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P    PL    + EG  +H  T I    +    + W    + + +  +F  +      +L
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTL 4298

Query: 697  DMLSLNIQD-SGEYTCRAVSATGVAETKAVLHVTPRA 732
             +  +N +D  GEY C A++ +G   T A L V  RA
Sbjct: 4299 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 4335



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 1/116 (0%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF-EARVEPQSDLTMTVEW 1079
            +Y+ +A   S +T    K+T   R    +K   + +E    H  +   E QS   +  +W
Sbjct: 4311 EYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQW 4370

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +  G++I  +++          +L+I   +  D G YT  A N  G    +A++TV
Sbjct: 4371 FKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 5/86 (5%)

Query: 3826 VSTPP-KFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP +F   ++  TVEE      EC V  +E+ K  ++W++NG  +    +Y  V D 
Sbjct: 5783 VKEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAK--VKWFKNGTEILKSKKYEIVADG 5839

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDF 3910
                L I     ED   Y C A  DF
Sbjct: 5840 RVRKLVIHDCTPEDIKTYTCDA-KDF 5864



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 60/258 (23%), Positives = 104/258 (40%), Gaps = 31/258 (12%)

Query: 89   AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCT 147
            A+FE +L       V W +  A + +  KY +      G V +L I +    DE EY+C 
Sbjct: 5894 ARFECEL-SRENAKVKWFKDGAEIKKGKKYDII---SKGAVRILVINKCLLDDEAEYSCE 5949

Query: 148  ARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKV 207
             R      + +V ++ E                 VSET       T     E S+   +V
Sbjct: 5950 VRTARTSGMLTV-LEEEAVFTKNLANI------EVSET------DTIKLVCEVSKPGAEV 5996

Query: 208  AYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEI--DRSLGPVSP 265
             +  G      D+  ++T  Y +L E   R  + +    E     +  +   R+ G V  
Sbjct: 5997 IWYKG------DEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKV 6050

Query: 266  PKIA----QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
             ++A     KP+N ++ EG  A+F   +S    P V W ++ + L + +K+++I      
Sbjct: 6051 HELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR 6109

Query: 322  TLRVRNTQKSDSGHYTLL 339
             L V++    D G Y ++
Sbjct: 6110 VLVVKDATLQDMGTYVVM 6127



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+ HL +    E D+  F C +  SR+    ++W+ N + +  G +YK   D S   L I
Sbjct: 6328 FVEHLEDQTVTEFDDAVFSCQL--SREKA-NVKWYRNGREIKEGKKYKFEKDGSIHRLII 6384

Query: 2836 THTYEEDSGIYTCKATNSKGSA 2857
                 +D   Y C   + K  A
Sbjct: 6385 KDCRLDDECEYACGVEDRKSRA 6406



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 10/101 (9%)

Query: 2947 WYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            W F  KVLE G R K+ +   +  L +      D GIYT K  N+        T+     
Sbjct: 6931 WCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR------VKTISGEID 6984

Query: 3007 DNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRP 3047
             N+I R   PK  +    I      L  EP   PDDD G P
Sbjct: 6985 VNVIARPSAPKELK-FGDITKDSVHLTWEP---PDDDGGSP 7021



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            ++I+  EG+ +           PT  + W  + K + +  R    +D     L++  +  
Sbjct: 7897 HDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVR 7954

Query: 2841 EDSGIYTCKATNSKGSATTSGSLRCTG 2867
             D+GIYT    N  GSAT S +++  G
Sbjct: 7955 ADAGIYTITLENKLGSATASINVKVIG 7981



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 4613 KPQTKAANAPPEIIE---PLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
            +P T A    P  +E    +K  I +  G+ +     + G+P+PT  W K +  +   + 
Sbjct: 8594 QPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRV 8653

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
              +     +  L I +A  +D G Y   A NS G    AA+++V
Sbjct: 8654 V-IDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8696



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/72 (25%), Positives = 30/72 (41%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             RF     G P+P  KW  +   IK    + + T +  S+L I+     D+  +     N 
Sbjct: 11032 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA 11091

Query: 4489  GGTAKCSANLVV 4500
              G+   + +L V
Sbjct: 11092 AGSKTVAVHLTV 11103



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 263   VSPPKIAQKPRNSKL---QEGADAQFQVQLSGNPRPRVTWFKNG-QRLINSNKHEIITTH 318
             + PP+I       KL   + G   +    + G P P+VTW K G   ++   + +++ T 
Sbjct: 12104 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTM 12163

Query: 319   NHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L + N+ + DSG Y+L   NP G
Sbjct: 12164 --AFLVIPNSTRDDSGKYSLTLVNPAG 12188



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 69/327 (21%), Positives = 120/327 (36%), Gaps = 22/327 (6%)

Query: 2933  GQVEPKNDPDLKIEWYFNGKVLEQGSRF-KLTSDFGFVTLDLVDVYERDSGIYTCKAYNK 2991
             G  EP   P +  ++ F      + +R  K+  D  FV  D  D    D G        +
Sbjct: 12576 GISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPD---SDGGSPIIGYLIE 12632

Query: 2992  RGEAFTSSTVYCTSKDNLIERTQHPKG--TEGLE---KIQNLEDSLRKEPGQQPDDDTGR 3046
             R E   +S ++  + D L+  T++P     EGLE   +I  L  +    P +  +  T R
Sbjct: 12633 RKER--NSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR 12690

Query: 3047  PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
              P       +++D+++  ++   A     G  S +I +F     +     +R   A   +
Sbjct: 12691 MPVDPPGKPEVIDVTKSTVSLIWARPKHDGG-SKIIGYFVEACKLPGDKWVRCNTAPHQI 12749

Query: 3107  VLE-ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK----SKGQKPRFTTHI--QNIE 3159
               E    T   +   Y  RA  +     IS   E  D     ++   PR    +  +++ 
Sbjct: 12750 PQEEYTATGLEEKAQYQFRAIARTA-VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12808

Query: 3160  GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
              +K G +   + TV     P   + W  +G  ++ +  IK         L++      DS
Sbjct: 12809 TVKAGTNVCLDATVF--GKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12866

Query: 3220  GEYVCRAYNKYGEDFTRATINCYGKGG 3246
             G+Y   A N  G       +    K G
Sbjct: 12867 GDYTITAENSSGSKSATIKLKVLDKPG 12893



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 4/103 (3%)

Query: 904   ESTQKPEFKTPIK--DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
             +  + P+ K  +K  D + +K G     EA +   G     +EW KDG+ +E ++++   
Sbjct: 14957 DDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS--GRPPPTMEWSKDGKELEGTAKLEIK 15014

Query: 962   FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                    L  K  T  D+G YT  A N  G A    N+ ++ +
Sbjct: 15015 IADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 15057



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/106 (21%), Positives = 47/106 (44%), Gaps = 4/106 (3%)

Query: 380   EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
             ++ +E+   ++ P+F        V  G+  R +  V G+P P + W   D++I +    +
Sbjct: 17120 KDEVELPRISMDPKFRDTIV---VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCE 17176

Query: 440   ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             I  N      L++ +    D G     A N +G  +F   + V+++
Sbjct: 17177 I-KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR 17221



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/105 (23%), Positives = 39/105 (37%), Gaps = 4/105 (3%)

Query: 902   VPESTQKPEFKTPIK--DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT 959
             V +  + P     +K  D I +K G      A +   G     + W KDG  +E  +R  
Sbjct: 19283 VKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIA--GRPLPVISWAKDGIEIEERARTE 19340

Query: 960   TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                   +  LT+K     D G Y     N  G  + + N  ++ K
Sbjct: 19341 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 2/92 (2%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             EF     D + IK G     +A ++  G    RV W KDG  +E    +      G  +L
Sbjct: 21462 EFGPEYFDGLIIKSGESLRIKALVQ--GRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSL 21519

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              ++  T    G YT  A NA G A     + +
Sbjct: 21520 FVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/79 (25%), Positives = 40/79 (50%)

Query: 4525  VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
             + SG+ +R+   V G     V W K+G +++  +  +I +  G+ +L + +A     G Y
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21532

Query: 4585  ECVAINSAGEARCDAECVV 4603
                A N++G A+ + +  V
Sbjct: 21533 TVEAKNASGSAKAEIKVKV 21551



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 502   VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
             VR G  + L     G PTP   W K    +    +  IHT    STL +     +DA  Y
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD--IHTTDSFSTLTVENCNRNDAGKY 21929

Query: 562   QCTAQNVAGS 571
               T +N +GS
Sbjct: 21930 TLTVENNSGS 21939



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%)

Query: 412   DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNK 470
             D  V G+P P++ W   D+++  D   K+ +  +G  A  +I     SDSG  T   +N 
Sbjct: 22571 DAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 22628

Query: 471   SGETAFQCRLNVIE 484
             SG  A    + V++
Sbjct: 22629 SGTKAVSVMVKVLD 22642



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 2648  LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             LK    +  G  + L   V  R  P   I W K G+ L + A + +T  + L  L ++ +
Sbjct: 22955 LKKTVTIRAGASLRLMVSVSGRPPP--VITWSKQGIDLASRAIIDTTESYSL--LIVDKV 23010

Query: 2708  RNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                D+G YT +A N  G+  +T  +K+ D
Sbjct: 23011 NRYDAGKYTIEAENQSGKKSATVLVKVYD 23039



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 643   LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
             +K VT   G       +I  VG P   I+W + G+ +  S ++         +L +++  
Sbjct: 24042 MKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEE 24099

Query: 703   IQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
              +D G YTC A +  G  ET  K +L  TP+
Sbjct: 24100 QEDEGVYTCIATNEVGEVETSSKLLLQATPQ 24130



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 785   GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
             G  A    Q+  V  P   ++WY+ G+ +  S +     +    +L +M    ED G YT
Sbjct: 24050 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 845   VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRY 880
               A N++GE + T+S ++  ++T     G P + +Y
Sbjct: 24108 CIATNEVGE-VETSS-KLLLQATPQFHPGYPLKEKY 24141



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 11/120 (9%)

Query: 2640  QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT-GARLK-STFDF 2697
             QAP F   L++ +   +  +  L  +V     P +K  W++ G  +   G + +   F  
Sbjct: 24429 QAPHFKEELRNLNVRYQS-NATLVCKVTGHPKPIVK--WYRQGKEIIADGLKYRIQEFKG 24485

Query: 2698  GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLH-PDSLDRIGAL 2756
             G   L I S+ +DD+ +Y  +ATN  G    TAS+++E     +   +H P +L+ +GA+
Sbjct: 24486 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-----VPAKIHLPKTLEGMGAV 24540



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 3/81 (3%)

Query: 2656  EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD-FGLVTLSINSLRNDDSGI 2714
             EGQ V  E +V     P LK  W K+G  L+ G  ++   +      L I     +D+G 
Sbjct: 25311 EGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGY 25368

Query: 2715  YTCKATNLLGEAVSTASIKIE 2735
             Y   ATN  G     A +++E
Sbjct: 25369 YRVTATNTAGSTSCQAHLQVE 25389



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 11/147 (7%)

Query: 3670 ESIQKLEETLHKREEITIEDEKPN-----PPRFTVEIKDNID---VPEGGPVHFDCRVEP 3721
            E  ++ ++ L +  +ITI   KP+     P     +I + I    V +G   HF  RV  
Sbjct: 1998 ELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRV 2055

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
            VG P    +W+ NG       R++    +     L I  + A D+     +A N  G  +
Sbjct: 2056 VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETS 2115

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEK 3807
            + A +   AK+ I    +L   ++ EK
Sbjct: 2116 SHAFLLVQAKQLITFTQELQDVVAKEK 2142



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F K  +D  V E K   F+C V+  P   V W  +D++++     KI   E   H L+I
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQ-KEKYVHRLLI 3070

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAF----QCRLNVIEKEQVVAPK 492
             +  +SD+G  T VA  N S    F      R+  I+KE  V  K
Sbjct: 3071 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 3115



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 3557 PPEFTTTPSDLILSEN----SSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            P +F     D+IL+E+    SSA FEC + P   S+    W  +G  +    + + I D 
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADG 4673

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
                L I  V   DAG YTC     + E T + KL V+
Sbjct: 4674 KDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 4711



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 85/408 (20%), Positives = 153/408 (37%), Gaps = 38/408 (9%)

Query: 1800 LFVQSKASLQLESQHESALQKIQQLEDSSRYQ-----RREDVEVAVNQA-PRFITQLNGP 1853
            L      S+Q E +  S   K   ++D+S+ +        + ++ V +  P F  +L   
Sbjct: 5471 LHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDY 5530

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
            T + E      +C I     P   V+W+ +GK ++         D     L +      D
Sbjct: 5531 TGV-EKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSD 5586

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQSKE-SIIRDSQHESALEKIQYLEDDS-RYKRAVQDD 1971
             G+YTC    + G   +S +L+++ +E  ++R       L  ++ +E ++ R++  + +D
Sbjct: 5587 IGQYTC----DCGTDKTSGKLDIEDREIKLVRP------LHSVEVMETETARFETEISED 5636

Query: 1972 SFVVEKPQFGKPI---KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
                     G+ +    + E+ E   +H         D T  V++           R K 
Sbjct: 5637 DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKP 5696

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNA--------VGEAVTTSSVKVDAKSG-LYLDT 2079
                    L  +   A +T T+ C+ +           G+ +  S   V    G ++  T
Sbjct: 5697 RVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLT 5756

Query: 2080 LDEQRLKKIQELEKYERP-KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPIND 2138
            L + +L+   E++   +  K        + PV  T     + ++EG  A  EC V   N 
Sbjct: 5757 LRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSREN- 5815

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186
                + WF NG +I    +Y    D     L I     ED  TY C A
Sbjct: 5816 --AKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 1/87 (1%)

Query: 4511  IVPPSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
             + PP+  L  ++ + +  G+   L  + +G     V W K+   V  D R  I     T 
Sbjct: 10318 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10377

Query: 4570  TLLILEAYPQDSGKYECVAINSAGEAR 4596
              L  ++A   DSGKY  V  NS G  +
Sbjct: 10378 ALEKIKAKRSDSGKYCVVVENSTGSRK 10404



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT-FFNFGYVA 968
             E    + + + +K G    F A +  +   T +  W  DG  ++     T    NF  V 
Sbjct: 11014 ELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEHYTVETDNFSSV- 11070

Query: 969   LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             LTIK+    D G Y     NA G  T + +LT++
Sbjct: 11071 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVL 11104



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 381   ERIEISEKALAPQF-VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD-DYNH 438
             E + + E    P   +K+     V  G   R +  V G+P+PEV W   D+   D   + 
Sbjct: 11693 EEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAW-TKDKDATDLTRSP 11751

Query: 439   KILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             ++ ++  + +    +T    SD G     A N +G       +NV++K
Sbjct: 11752 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDK 11799



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 4511  IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             ++PP   +  Q + + +G+ +R++  V G       W K   +V       + + D +  
Sbjct: 12400 LLPPKILMPEQ-ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 12458

Query: 4571  LLILEAYPQDSGKYECVAINSAG 4593
             L+I +   +DSG Y   A NS+G
Sbjct: 12459 LIIKDVTRKDSGYYSLTAENSSG 12481



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/66 (28%), Positives = 33/66 (50%)

Query: 1874  PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             P   V W  +G +L+     + +       L++ +V  +DSG+YT  A N+ G   ++I+
Sbjct: 12826 PMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 12885

Query: 1934  LNVQSK 1939
             L V  K
Sbjct: 12886 LKVLDK 12891



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 2/81 (2%)

Query: 85    QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
             +  N + +  ++G P P VSW + + PL    + S+       + +L++      D G+Y
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV--ESSAVNTTLIVYDCQKSDAGKY 13556

Query: 145   TCTARNQYGEAICSVYIQPEG 165
             T T +N  G    ++ I+  G
Sbjct: 13557 TITLKNVAGTKEGTISIKVVG 13577



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 1/88 (1%)

Query: 915   IKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSV 974
             IKD ++IK G      A +  +G    +  W K G+ +  S             LTIK  
Sbjct: 13887 IKDGLTIKAGDTIVLNA-ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYA 13945

Query: 975   TVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             T  DAG YT  A N  G       +T++
Sbjct: 13946 TRKDAGEYTITATNPFGTKVEHVKVTVL 13973



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%)

Query: 4508  RGGIVPPSFTLTAQ---NVNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKIL 4563
             R  + PP  ++  +    + V +G+  ++D  + G KPI  + W+K  +++    R +I 
Sbjct: 16038 RDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG-KPIPTIQWIKGDQELSNTARLEIK 16096

Query: 4564  EEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
               D   +L + +A   DSG Y   A N AGE
Sbjct: 16097 STDFATSLSVKDAVRVDSGNYILKAKNVAGE 16127



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/72 (31%), Positives = 33/72 (45%)

Query: 499   TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             T+ V  GE   ++A   G P P I W K    +     L I +   A++L +  A   D+
Sbjct: 16055 TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 16114

Query: 559   AWYQCTAQNVAG 570
               Y   A+NVAG
Sbjct: 16115 GNYILKAKNVAG 16126



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQKPR---NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             V  P+I+  P+      +  G   + +  + G P P + W +  + +  S + EI  T  
Sbjct: 17123 VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17182

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
                L V++  + D G Y L A N  G
Sbjct: 17183 KALLIVKDAIRIDGGQYILRASNVAG 17208



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 2/56 (3%)

Query: 2404  GDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             G P   +EW R +K IE+S+R   K  DF  + +    +R  D G Y+ RASN+ G
Sbjct: 17154 GKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIR-IDGGQYILRASNVAG 17208



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/68 (32%), Positives = 28/68 (41%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             + VR G  V L     G P P I+W KDG+P+  +  +R        TL I  AK     
Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21135

Query: 560   WYQCTAQN 567
              Y     N
Sbjct: 21136 KYTVILDN 21143



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 1055  IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
             I  G+S   +A V+ +      V W+ +G +I     ++     G  +L +     +  G
Sbjct: 21473 IKSGESLRIKALVQGRP--VPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21530

Query: 1115  VYTVVARNAAGEAQLSASMTVE 1136
             VYTV A+NA+G A+    + V+
Sbjct: 21531 VYTVEAKNASGSAKAEIKVKVQ 21552



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 6/78 (7%)

Query: 85    QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
             QGG  +    ++G P P+  WT++   +   +K +M    +T    L+IK+   GD G Y
Sbjct: 23653 QGGVIRLTIPIKGKPFPICKWTKEGQDI---SKRAMIATSET-HTELVIKEADRGDSGTY 23708

Query: 145   TCTARNQYGEAICSVYIQ 162
                  N+ G+   +VYI+
Sbjct: 23709 DLVLENKCGKK--AVYIK 23724



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 2/81 (2%)

Query: 3989  ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
             E  +  CQ+  VG P   ++W+  GK L+   ++    D     +       ED G Y C
Sbjct: 24051 EAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC 24108

Query: 4049  RATNLYGMDETKAVIKTTGKP 4069
              ATN  G  ET + +     P
Sbjct: 24109 IATNEVGEVETSSKLLLQATP 24129



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 2522  EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
             EGQ+  +   +   G+PS   EW+ N + + + S    +      +L+I +   +D+G Y
Sbjct: 26650 EGQNVLFTCEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 26707

Query: 2582  MCKAINRAG 2590
               KA N  G
Sbjct: 26708 TIKAKNFRG 26716



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I  L ++ C E  N+ FE  +  S    + + W F +K +   ++YK         L + 
Sbjct: 2490 IRGLRDLTCTETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVL 2546

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            +  ++D G YT  A    G   TSG L   G
Sbjct: 2547 NMMKDDEGKYTFYA----GENITSGKLTVAG 2573



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 5/98 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P+   P+ D    E    H    +    +    V W      + +  +   + D     L
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTL 4298

Query: 1771 NMKYVNPED-SGTYTCRAINELGEAVTSSTLFVQSKAS 1807
             +  VN ED  G Y C A+N+ G+  TS+ L V  +A+
Sbjct: 4299 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 4336



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA-MNFGWVYPEDSGEYLCRA 4050
            KF C++     PN++ +WF  G+ +   ++ + I    Y++ +        D GEY C+A
Sbjct: 4355 KFTCEIQSA--PNVRFQWFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEYTCKA 4411

Query: 4051 TNLYGMDETKAVIKTT 4066
            +N YG     A +  T
Sbjct: 4412 SNEYGSVSCTATLTVT 4427



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+  T       + EG    LE +V      N K++WFKNG  +    + +   D 
Sbjct: 5783 VKEPPVEFTKPLEDQTVEEGATAVLECEVSRE---NAKVKWFKNGTEILKSKKYEIVADG 5839

Query: 2698 GLVTLSINSLRNDDSGIYTCKA 2719
             +  L I+    +D   YTC A
Sbjct: 5840 RVRKLVIHDCTPEDIKTYTCDA 5861



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            P +F+  ++D T + E   A F  +L         V+W+ NG+++  G +Y+   D  I 
Sbjct: 6325 PTEFVEHLEDQT-VTEFDDAVFSCQL---SREKANVKWYRNGREIKEGKKYKFEKDGSIH 6380

Query: 3341 ILDILYCYEENSGEYECVATNKLGR 3365
             L I  C  ++  EY C   ++  R
Sbjct: 6381 RLIIKDCRLDDECEYACGVEDRKSR 6405



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 17/69 (24%), Positives = 34/69 (49%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            ++ G   +    ++G P P++TW K    L    +  I      +T+ + ++++SD+G Y
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7264

Query: 337  TLLAENPNG 345
             + A N  G
Sbjct: 7265 IIEAVNVCG 7273



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P   +   DI V E +          V  P   V W ++G  ++AS+RLT  +D     L
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHL 7947

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTS 1797
             +      D+G YT    N+LG A  S
Sbjct: 7948 EVPKSVRADAGIYTITLENKLGSATAS 7974



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 8/77 (10%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE---DSSRITK---THDFGYVSMTISHV 2441
            ++ G+  H    +   G P  K+EW +NE +IE   D+ +ITK   +       ++I   
Sbjct: 8913 VKAGEPVHIPADV--TGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 8970

Query: 2442 RDEDEGVYMCRASNLLG 2458
              ED+G Y   ASN LG
Sbjct: 8971 VREDKGTYTVTASNRLG 8987



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/108 (22%), Positives = 47/108 (43%), Gaps = 6/108 (5%)

Query: 381   ERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
             E + + ++   P+ +    + +++ +  G   R    + G P+P+VTW   DR       
Sbjct: 10708 EPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA--PTK 10765

Query: 438   HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
              +I V   G+  L I N    D G+ +    N +G      ++ V++K
Sbjct: 10766 ARIDVTPVGS-KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 10812



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 4512  VPPSFTLTAQN---VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568
             VPP   L+      + V +G  V LD  V G     V W K+G  ++P    K+  +   
Sbjct: 12794 VPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL 12853

Query: 4569  YTLLILEAYPQDSGKYECVAINSAG 4593
              TL +     +DSG Y   A NS+G
Sbjct: 12854 CTLELFSVNRKDSGDYTITAENSSG 12878



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 485   KEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             ++ V APK    V+   T+ ++ GE   L A   G P P + W KDG  +    +L I  
Sbjct: 14956 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15015

Query: 542   DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                ++ L    +   D+  Y  TA N  G
Sbjct: 15016 ADFSTNLVNKDSTRRDSGAYTLTATNPGG 15044



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/68 (29%), Positives = 30/68 (44%)

Query: 503   REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             + GE V +     G P P +TW+KD   +  +    I     +S L IP+   +D   Y 
Sbjct: 20787 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20846

Query: 563   CTAQNVAG 570
              T +N  G
Sbjct: 20847 LTIENGVG 20854



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             +  G+++ ++  ++  G P  RV WF +G  +      +     G  +L +  AT    G
Sbjct: 21473 IKSGESLRIKALVQ--GRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21530

Query: 1249  EYTVRAVNHLGSAHTSAIVRV 1269
              YTV A N  GSA     V+V
Sbjct: 21531 VYTVEAKNASGSAKAEIKVKV 21551



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/76 (26%), Positives = 32/76 (42%)

Query: 4637  GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
             G        I G+P P V W   +  +K +    ++ T D  TL + ++   D G Y   
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22224

Query: 4697  AYNSAGRVTVAAKLKV 4712
               N+AG  T +  + V
Sbjct: 22225 LENTAGVKTFSVTVVV 22240



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 1846 FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALD 1905
            F+ +L    ++ E  S   EC + P    N+  +WY N   L+S  +Y  ++  G   L 
Sbjct: 2223 FVKELQD-IEVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2278

Query: 1906 ILTVYGEDSGEYT 1918
            +  V  ED GEY+
Sbjct: 2279 VKDVTKEDQGEYS 2291



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            +   TV ES+   FEC V    +P  + EW R+GK LP  +  R+  D     L I    
Sbjct: 2580 LTDQTVAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATK 2636

Query: 3896 AEDSGEY 3902
             +D GEY
Sbjct: 2637 LDDIGEY 2643



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            ++E Q A +EC +    +P+ + EW  +GK L   +  R+ +D     L I     +D G
Sbjct: 2585 VAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIG 2641

Query: 1916 EYTCKAINNLGQA---VSSIRLNVQSKESIIRDSQ 1947
            EYT K   +   A   V ++++    K   + ++Q
Sbjct: 2642 EYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQ 2676



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDI-LYCYEENSGEYECVATNKLGRDSTKANL 3372
            +V W++  K +P   +++   D     L I     E++ GEY C A N  G+ +T A L
Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4329



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 6/82 (7%)

Query: 1459 GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDLIAEDSGIY 1517
            G    F C+++     N++ +WFK G+ +    +   I    Y++ L+I+     D G Y
Sbjct: 4351 GHLAKFTCEIQSAP--NVRFQWFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEY 4407

Query: 1518 TCRAVNLVGTDEVSCRLTCRST 1539
            TC+A N  G+  VSC  T   T
Sbjct: 4408 TCKASNEYGS--VSCTATLTVT 4427



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 5/91 (5%)

Query: 626  PPGEEDRVYP----PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIE-WLKNGQSIE 680
            PP E    Y     P +F+  +K +   E   +      E +  P+  I  W+K+G +I 
Sbjct: 4603 PPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIR 4662

Query: 681  ASSRFTSIFRFGYISLDMLSLNIQDSGEYTC 711
             S +   I       L ++ + + D+GEYTC
Sbjct: 4663 ESPKHRFIADGKDRKLHIIDVQLSDAGEYTC 4693



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 2380 QPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTIS 2439
            +PL+++  +  G+TA FDC L     P   VEW+   K +E S ++    +    ++T+ 
Sbjct: 5703 RPLKDV-TVTAGETATFDCELSYEDIP---VEWYLKGKKLEPSDKVVPRSEGKVHTLTLR 5758

Query: 2440 HVRDEDEG 2447
             V+ ED G
Sbjct: 5759 DVKLEDAG 5766



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 5/79 (6%)

Query: 3557 PP--EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP  EF    +DL + E   A FEC L   N    +V+WF +G  +  G +   I+    
Sbjct: 5874 PPHVEFLRPLTDLQVREKEMARFECELSREN---AKVKWFKDGAEIKKGKKYDIISKGAV 5930

Query: 3615 VILEIGGVYQRDAGLYTCK 3633
             IL I      D   Y+C+
Sbjct: 5931 RILVINKCLLDDEAEYSCE 5949



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)

Query: 4113 FVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            F+S P  + + EGE A F C ++    P V W  +  T+ +G +Y +  DG
Sbjct: 6057 FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADG 6106



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 14/123 (11%)

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
            F   A N  G +K SA +   + +R      +PPS  L  + + V  G  V +  K+ G 
Sbjct: 9592 FRVKAVNAAGVSKPSATVGPCDCQRPD----MPPSIDLK-EFMEVEEGTNVNIVAKIKGV 9646

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEE--------DGTYTLLILEAYPQDSGKYECVAINSA 4592
                + W K   K +PD +  +L +        D T TL+I ++   D+G Y   A+N+ 
Sbjct: 9647 PFPTLTWFKAPPK-KPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9705

Query: 4593 GEA 4595
            G A
Sbjct: 9706 GTA 9708



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 2230  TRIEVE-EPKISPPRFVTELRGTTH--VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ 2286
             T I +E + K+ PP    +++      V  G T  F   +  V  P  +  +  +G  ++
Sbjct: 10998 TTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIK 11055

Query: 2287  SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             +   + +  D     L I++C+  D GEY +   NA G  T A+ +TV
Sbjct: 11056 TDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 5/105 (4%)

Query: 3685  ITIE-DEKPNPPRFTVEIK--DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
             I IE  EK  PP   +++K  + + V  G  V F   +  V  PT +  W  +G    T 
Sbjct: 11000 IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTD 11057

Query: 3742  SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
                    D     L I     RD GEY    +N  GS T    +T
Sbjct: 11058 EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 11102



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 3/86 (3%)

Query: 4511  IVPPSFTLTAQNVN---VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567
             +VPPS  L  + +    V +G  VR    + G       W  +G +++ D    +  ++ 
Sbjct: 11008 LVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNF 11067

Query: 4568  TYTLLILEAYPQDSGKYECVAINSAG 4593
             +  L I     +D+G+Y+    N+AG
Sbjct: 11068 SSVLTIKNCLRRDTGEYQITVSNAAG 11093



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/70 (27%), Positives = 29/70 (41%)

Query: 4001  GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
             G P   + W   GK L+ + R   I D   V +        D G+Y+  A N  G  +  
Sbjct: 11437 GRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 11496

Query: 4061  AVIKTTGKPG 4070
             A++    +PG
Sbjct: 11497 AIVNVLDRPG 11506



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/80 (26%), Positives = 30/80 (37%)

Query: 4633  IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             +  E         I GKP P+V W KG+  +       +  +A   TL + +    D G 
Sbjct: 13496 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13555

Query: 4693  YKCVAYNSAGRVTVAAKLKV 4712
             Y     N AG       +KV
Sbjct: 13556 YTITLKNVAGTKEGTISIKV 13575



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 2905  DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLT- 2963
             D E PK +  +       L  G+   LE  V  +  P +  EW  +GK LE  ++ ++  
Sbjct: 14958 DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTM--EWSKDGKELEGTAKLEIKI 15015

Query: 2964  SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
             +DF    L   D   RDSG YT  A N  G A
Sbjct: 15016 ADFS-TNLVNKDSTRRDSGAYTLTATNPGGFA 15046



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/69 (27%), Positives = 31/69 (44%)

Query: 1737  VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
             +G P   V W ++ VP++ + R+          L +K    ED G Y  +  N  GEA+ 
Sbjct: 15675 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 15734

Query: 1797  SSTLFVQSK 1805
             +  + V  K
Sbjct: 15735 TLNVIVLDK 15743



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/86 (20%), Positives = 34/86 (39%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             +  + EV   G P P I W ++  P+K +    +      + L I++   +D   +    
Sbjct: 16748 QDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITV 16807

Query: 4486  ENRGGTAKCSANLVVEEKRRQGRGGI 4511
              N  G    S  +V  +K    +G +
Sbjct: 16808 ANVVGQKTASIEIVTLDKPDPPKGPV 16833



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/61 (34%), Positives = 29/61 (47%)

Query: 2803  PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
             P   I W  + +PL   TR       +   L I    ++D G YT  ATNS G+AT + S
Sbjct: 17842 PRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLS 17901

Query: 2863  L 2863
             +
Sbjct: 17902 V 17902



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 16/78 (20%), Positives = 34/78 (43%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             EQ + +V F G P   + W ++   +K +    + +  T + L I++   ED   +    
Sbjct: 18913 EQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 18972

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N  G+      ++V ++
Sbjct: 18973 SNSAGSITVPITIIVLDR 18990



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             G  V L A +  +  P   IEW+K+   L T A +       L ++ I      +SG Y 
Sbjct: 20390 GTSVKLRAGISGKPAPT--IEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYE 20447

Query: 2717  CKATNLLGEAVSTASIKIEDR 2737
              K  N +G A +T  ++I D+
Sbjct: 20448 LKLRNAMGSASATIRVQILDK 20468



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 2/99 (2%)

Query: 4606  PATKDKPKPQTKAANAPP-EIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
             P   ++P        AP  ++   L+  ++A+ G+ ++      G+P PTV W K +K +
Sbjct: 20756 PIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL 20815

Query: 4664  KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                  + +  T     L I +    D G Y     N  G
Sbjct: 20816 GSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/96 (28%), Positives = 38/96 (39%)

Query: 4522  NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
             +V   +G+ V++     G  P  V W K+ K +  D R  I   D +  L I +    D+
Sbjct: 20783 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDT 20842

Query: 4582  GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
             GKY     N  GE +     V  L       K Q K
Sbjct: 20843 GKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVK 20878



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 2/72 (2%)

Query: 499   TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             T+ +R G  + L     G P P ITW K G+ +       I T    S L + +    DA
Sbjct: 22958 TVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTTESYSLLIVDKVNRYDA 23015

Query: 559   AWYQCTAQNVAG 570
               Y   A+N +G
Sbjct: 23016 GKYTIEAENQSG 23027



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 3/97 (3%)

Query: 905   STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
             S + P  +  +KD ++ K G  A    ++  +G     ++W + G+ +  S +     + 
Sbjct: 24032 SGEAPGIRKEMKD-VTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDG 24088

Query: 965   GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                 LT+ +    D G YTC A N +G+  TS+ L +
Sbjct: 24089 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLL 24125



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 1192  GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
             G+   L C++  +G P   ++W+  G+ +    ++K   D     L ++     D G YT
Sbjct: 24050 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 1252  VRAVNHLGSAHTSA 1265
               A N +G   TS+
Sbjct: 24108 CIATNEVGEVETSS 24121



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 41/163 (25%), Positives = 65/163 (39%), Gaps = 10/163 (6%)

Query: 4357  GKEVHVAKQKQTQKEVVGDKE--ITRKITSTETTEIEHKAQTQERVVEGPVK-----PSK 4409
             GKE+     K   +E  G     I   +T  + T  + +A  Q   V G        P+K
Sbjct: 24468 GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 24527

Query: 4410  P--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTFSTKS 4466
                P   + M        E    ++ F G+P P+I W +    I N+  +Q I T S  S
Sbjct: 24528 IHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTS 24587

Query: 4467  ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
             ++    V  +D+  +   A+NR G  + +  L V +     RG
Sbjct: 24588 LVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG 24630



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/66 (27%), Positives = 33/66 (50%)

Query: 2936  EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
             E   +P  +IEW+ N   +   S   ++      +L++ +    DSG YT KA N RG+ 
Sbjct: 26659 EISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQC 26718

Query: 2996  FTSSTV 3001
               ++++
Sbjct: 26719 SATASL 26724



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V R  PV  + ++ ++ +  G  A F C +     P ++ +WF+  + I +S + +    
Sbjct: 4332 VKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSS 4388

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                S+ I   +  D G Y C+ASN  G
Sbjct: 4389 KYISSLEILRTQVVDCGEYTCKASNEYG 4416



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 4091 EASWQVTPEQVVEESKAR-CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            E S+Q    +     K +  P +F++    V V E + A+F C V+  PK    WL    
Sbjct: 5322 EVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQ 5380

Query: 4150 TIVNGSRYKLTYDGMYHFDIPKTRQYD 4176
             I    R++L  DG  H  + K+  ++
Sbjct: 5381 EITGDDRFELIKDGTKHSMVIKSAAFE 5407



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 6/79 (7%)

Query: 3281 PP--KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            PP  +F+  + D+ ++ E + A FE  L      + KV+WF +G ++  G +Y       
Sbjct: 5874 PPHVEFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGA 5929

Query: 3339 IVILDILYCYEENSGEYEC 3357
            + IL I  C  ++  EY C
Sbjct: 5930 VRILVINKCLLDDEAEYSC 5948



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 5/78 (6%)

Query: 3829 PP--KFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            PP  +F+  +    V E E  RFEC +  +E+ K  ++W+++G  +  G +Y  +     
Sbjct: 5874 PPHVEFLRPLTDLQVREKEMARFECELS-RENAK--VKWFKDGAEIKKGKKYDIISKGAV 5930

Query: 3887 VSLDILYVYAEDSGEYIC 3904
              L I     +D  EY C
Sbjct: 5931 RILVINKCLLDDEAEYSC 5948



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 3/91 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   +E  D I V EG  +        V  PT  + W  +G+      R+   ND     
Sbjct: 7890 PTIDLETHDII-VIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAH 7946

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L++      DAG YT    NK GSAT +  +
Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATASINV 7977



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 60   PITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR---KKAPLVECN 116
            P    RP  P P I  + F      +G N     K++G P P ++W +   KK    E  
Sbjct: 9611 PCDCQRPDMP-PSIDLKEFMEVE--EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPV 9667

Query: 117  KYSMRYNEQTGD--VSLLIKQIGPGDEGEYTCTARNQYGEA 155
             Y    N+   D   +L+I Q    D G YT TA N  G A
Sbjct: 9668 LYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTA 9708



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             E     +D I+++ G      AR++  G     + W K+G+ +    R+    +   V L
Sbjct: 11412 ELDVTCRDVITVRVGQTIRILARVK--GRPEPDITWTKEGKVLVREKRVDLIQDLPRVEL 11469

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
              IK     D G Y   A N+ G A  SA + ++ +
Sbjct: 11470 QIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDR 11504



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 3/91 (3%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKL--IKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
             V  G  I     + GKP P V W K      +  S   ++   AD     +++A   D G
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11775

Query: 4692  DYKCVAYNSAGRVTVAAKLKV-TQPDQADNL 4721
              Y   A N+AG     A + V  +P    NL
Sbjct: 11776 KYVVTATNTAGSFVAYATVNVLDKPGPVRNL 11806



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             V  G N+ L+  +   G P   V W  +G  +      K         L++      D+G
Sbjct: 12810 VKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12867

Query: 1249  EYTVRAVNHLGSAHTSAIVRVIER 1272
             +YT+ A N  GS   +  ++V+++
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDK 12891



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 6/79 (7%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS--LLIKQIGPGDEGE 143
             G N K E  + G P P V+W  KK    +  K + R N +T   S  L I +    D G 
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTW--KKGD--QILKQTQRVNFETTATSTILNINECVRSDSGP 14638

Query: 144   YTCTARNQYGEAICSVYIQ 162
             Y  TARN  GE    + IQ
Sbjct: 14639 YPLTARNIVGEVGDVITIQ 14657



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/78 (24%), Positives = 35/78 (44%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  R E +  G P P ++W ++   ++ +   +I      + L+ +     DS  +   A
Sbjct: 14980 EAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 15039

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N GG AK   N+ V ++
Sbjct: 15040 TNPGGFAKHIFNVKVLDR 15057



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 4425  HEQARFEVEFD--GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFA 4482
             H    F+V+ D  G+P+P I+W + +  + N+   +I +    + L ++     DS  + 
Sbjct: 16059 HAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYI 16118

Query: 4483  AVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
               A+N  G    + N+ V ++     G +V
Sbjct: 16119 LKAKNVAGERSVTVNVKVLDRPGPPEGPVV 16148



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 1/60 (1%)

Query: 3174  VPVDD-PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             VP+   P   I W  +G P++ +TRI          L I  T   D G+Y     N  G+
Sbjct: 16754 VPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 16813



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 2/72 (2%)

Query: 3716  DCRVE-PV-GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT 3773
             D ++E PV G P   I W  +G P    +RV+         L I      D G+YT  AT
Sbjct: 17831 DLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTAT 17890

Query: 3774  NKWGSATTTAKI 3785
             N  G+AT    +
Sbjct: 17891 NSAGTATENLSV 17902



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 4/60 (6%)

Query: 96    RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQYGE 154
             +G P P V+W + +  L    +YS+   E T   SLL I Q+   D G+Y  T  N  GE
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSI---ENTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20855



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
             V  G+       + GRP P  +WF    ++R+  + ++ V      A L I   T+ D+G
Sbjct: 23253 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRE--SERVTVETHTKVAKLTIRETTIRDTG 23310

Query: 462   VVTCVARNKSGETAFQCRLNVIEK 485
               T   +N +G T+   ++ +++K
Sbjct: 23311 EYTLELKNVTGTTSETIKVIILDK 23334



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 1/98 (1%)

Query: 4714  QPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
             QP   D+ P +T  +R   V  GQ  +F   + SK    ++W   G  + E+      + 
Sbjct: 25869 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 25928

Query: 4773  GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                  L I + + +D+GT+    T   G+    A L V
Sbjct: 25929 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 4/62 (6%)

Query: 2656  EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
             EGQ + L+A +   TD    ++W  NGV LT     +        TL+I    + D GI 
Sbjct: 26555 EGQRLVLKANIAGATD----VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGIL 26610

Query: 2716  TC 2717
             TC
Sbjct: 26611 TC 26612



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 50    TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
             TQ+ESS  +  + AG  G   PP  E +  +    +G          G PTP V+W+   
Sbjct: 26813 TQLESSTSKM-LKAGIRG--IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWS-CG 26868

Query: 110   APLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
                +   +    + E T D+ +L+I  +   D G YT +  N++G    +V I
Sbjct: 26869 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 26921



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 5/94 (5%)

Query: 3694  PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLNDFG 3751
             PP+    +  +I + EG  +   C     G+PT  + W   GR   +    R H  N   
Sbjct: 26831 PPKIEA-LPSDISIDEGKVLTVACAF--TGEPTPEVTWSCGGRKIHSQEQGRFHIENTDD 26887

Query: 3752  FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                L I  +  +D G YT    N++GS + T  I
Sbjct: 26888 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 26921



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++  +++G       R+   G PT  V+++R+   I+ S     + +    S
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+    ED G Y   A+N +G
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVG 183



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 765  QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824
            Q  Q   F + LQD+   ++   A FE +    S+P ++V+WYKDG  +    +     +
Sbjct: 2123 QAKQLITFTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSD 2179

Query: 825  FGYVSLNIMHLRAEDAGSYT 844
                 L+I+ +   DA  Y+
Sbjct: 2180 RKVHFLSILTIDTSDAEDYS 2199



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 7/143 (4%)

Query: 3559 EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILE 3618
            EF     D+ + E+ S   EC + P N   +  +W+HN   L +  +    +  G   L 
Sbjct: 2222 EFVKELQDIEVPESYSGELECIVSPEN---IEGKWYHNDVELKSNGKYTITSRRGRQNLT 2278

Query: 3619 IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEET 3678
            +  V + D G Y+       G+ T +CKL++K R   IL+         G     +++ +
Sbjct: 2279 VKDVTKEDQGEYSFVI---DGKKT-TCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS 2334

Query: 3679 LHKREEITIEDEKPNPPRFTVEI 3701
            L   E + ++D +   P   V I
Sbjct: 2335 LESVEGVWMKDGQEVQPSDRVHI 2357



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%)

Query: 4110 PPVFVSLP-DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PPV  + P +  TVEEG  A   C V+     +V W  NG  I+   +Y++  DG
Sbjct: 5786 PPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADG 5839



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF  +L NI   E D I   C V     P  ++ W+  ++ +    RY+   +     L 
Sbjct: 5967 VFTKNLANIEVSETDTIKLVCEVSK---PGAEVIWYKGDEEIIETGRYEILTEGRKRILV 6023

Query: 2835 ITHTYEEDSGIYTCKATNSK 2854
            I + + ED+G Y C+  +S+
Sbjct: 6024 IQNAHLEDAGNYNCRLPSSR 6043



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
            YP P     W F  KVL++G R +      +A L I      D G YT K  N +     
Sbjct: 6924 YPRPT--ATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 6981

Query: 1931 SIRLNVQSKES 1941
             I +NV ++ S
Sbjct: 6982 EIDVNVIARPS 6992



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 6/120 (5%)

Query: 2219 KIRQLEAQGHSTRIEVEEPKISP-PRFVTELRGTTH---VFEGKTAHFECQVEPVHDPNL 2274
            ++R + A G S   E+ E  ++  P     +   TH   V EG+          V  P  
Sbjct: 7862 RVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT- 7920

Query: 2275 RIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             + ++ +GK ++++ R  +  D     L++   V  DAG Y++   N LG  T++I++ V
Sbjct: 7921 -VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 1567 TDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKV---EWYHNNKPLKSG 1623
            +++ + V  + P C  ++ ++E  +      E+  IPV    + V    W+ + K +K+ 
Sbjct: 7875 SEISENVVAKDPDCKPTI-DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS 7933

Query: 1624 SRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
             R T  N+     L++   +  D+G YT    N LG A  S
Sbjct: 7934 DRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATAS 7974



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 4/102 (3%)

Query: 3684  EITIEDEKPNPPRFTVEI--KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
             E  I  +  +PP   +++  +D I V  G  +    RV+  G P   I W   G+     
Sbjct: 11398 ESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVK--GRPEPDITWTKEGKVLVRE 11455

Query: 3742  SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
              RV  + D   + L I      D G+Y   A N  G A  +A
Sbjct: 11456 KRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSA 11497



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 2/78 (2%)

Query: 1859  GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
             GQ+     R++  P+P+  + W   GKVL    R     D     L I      D G+Y 
Sbjct: 11426 GQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 11483

Query: 1919  CKAINNLGQAVSSIRLNV 1936
               A N+ G A  S  +NV
Sbjct: 11484 ISAKNSSGHAQGSAIVNV 11501



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
             G   +   +++G P P ++WT++   LV   +  +   +    V L IK+    D G+Y 
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI--QDLPRVELQIKEAVRADHGKYI 11483

Query: 146   CTARNQYGEA 155
              +A+N  G A
Sbjct: 11484 ISAKNSSGHA 11493



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/126 (22%), Positives = 48/126 (38%)

Query: 3121  YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
             +  +  N+ G+++     E V K   QKP     +  +  +K G +   E  V     P+
Sbjct: 11676 FRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPE 11735

Query: 3181  MKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             +      +   +  S R+K  +        +   +  D G+YV  A N  G     AT+N
Sbjct: 11736 VAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVN 11795

Query: 3241  CYGKGG 3246
                K G
Sbjct: 11796 VLDKPG 11801



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/60 (30%), Positives = 29/60 (48%)

Query: 1076  TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             TV W  +G  +  A  I+         L++ SV  +DSG YT+ A N++G    +  + V
Sbjct: 12829 TVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 12888



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 4/85 (4%)

Query: 782   LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI-TSIFNFGYVSLNIMHLRAEDA 840
             L+ G     EA ++    PTM  EW KDG+ +  ++++   I +F    +N    R  D+
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTM--EWSKDGKELEGTAKLEIKIADFSTNLVNKDSTR-RDS 15032

Query: 841   GSYTVRAVNKLGEAISTASIRVAAR 865
             G+YT+ A N  G A    +++V  R
Sbjct: 15033 GAYTLTATNPGGFAKHIFNVKVLDR 15057



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/65 (32%), Positives = 29/65 (44%)

Query: 1608  TLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIA 1667
             T  V W+ +N PLK  +R    +      L I     ED G Y  +  N+ GEA+ +   
Sbjct: 15679 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV 15738

Query: 1668  IVHSK 1672
             IV  K
Sbjct: 15739 IVLDK 15743



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/172 (19%), Positives = 67/172 (38%), Gaps = 14/172 (8%)

Query: 1246  DTGEYTVRAVNHLGSAHT---SAIVRVIERSDIVTD-TQNEQAIEQIQLLEDAARRTKQ- 1300
             D G   ++ +  + + H+   S   RV     ++T+ TQ E+ + ++  + +  R   + 
Sbjct: 16660 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRS 16719

Query: 1301  -----VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                  V +D+ +   P    A  +     G ++ +E  +   G     + W  +G P+K 
Sbjct: 16720 LAVPIVAKDLVI--EPDVKPAFSSYSVQVGQDLKIEVPIS--GRPKPTITWTKDGLPLKQ 16775

Query: 1356  GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407
               R       D   L +   + +D G Y     N +G+   S  +  + K D
Sbjct: 16776 TTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD 16827



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 2/90 (2%)

Query: 3054  FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGT 3113
             F+D + ++ G+    EA +   G     IEW    K IE S R          +L +   
Sbjct: 17134 FRDTIVVNAGETFRLEADV--HGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDA 17191

Query: 3114  KTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
                D G Y  RA+N  G     V ++ +D+
Sbjct: 17192 IRIDGGQYILRASNVAGSKSFPVNVKVLDR 17221



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 16/70 (22%), Positives = 34/70 (48%)

Query: 276   KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335
             K + G   + +  +SG P P + W+K+ + L  +    +  T +  ++ +++  + +SG 
Sbjct: 20386 KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGC 20445

Query: 336   YTLLAENPNG 345
             Y L   N  G
Sbjct: 20446 YELKLRNAMG 20455



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/60 (28%), Positives = 26/60 (43%)

Query: 945   WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
             W   G  +  S R+T   +     LTI+  T+ D G YT    N  G  + +  + I+ K
Sbjct: 23275 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDK 23334



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM-IHEGNNAVLLIGNTYE 4785
            +++  + EG    F  +++    P I W ++G  I     +QM   +   A L I     
Sbjct: 1251 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLP 1310

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            ED G +T  A+   G    S KL V+
Sbjct: 1311 EDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 2122 KEGDR-AHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            KE D  A FEC     ++P + + W+ +G ++  G +YR   D     L IL     D+ 
Sbjct: 2140 KEKDTMATFECET---SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAE 2196

Query: 2181 TYMC 2184
             Y C
Sbjct: 2197 DYSC 2200



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            F + LQ+I+ + E  +   +C + P     ++ +W+ N+  ++ + + T T   G  ++T
Sbjct: 2223 FVKELQDIE-VPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2278

Query: 2438 ISHVRDEDEGVY 2449
            +  V  ED+G Y
Sbjct: 2279 VKDVTKEDQGEY 2290



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 910  EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
            EF+  IKD I + E   A FE     + +  + V+W+KD + ++ + RI          L
Sbjct: 3013 EFRKHIKD-IKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRL 3068

Query: 970  TIKSVTVHDAGHYTCRAYNAIGQA 993
             I S  + DAG YT  A   +  A
Sbjct: 3069 LIPSTRMSDAGKYTVVAGGNVSTA 3092



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 5/93 (5%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
            +    P+  T L +   +EG   H    +    +    V WY  NK + S  +F    + 
Sbjct: 4238 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQ 4293

Query: 1633 GFVALDIMSCLPED-SGTYTCRAINALGEAVTS 1664
                L I     ED  G Y C A+N  G+  TS
Sbjct: 4294 NTYTLVIDKVNTEDHQGEYVCEALNDSGKTATS 4326



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/165 (22%), Positives = 61/165 (36%), Gaps = 11/165 (6%)

Query: 395  VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMIT 453
            VK  +D+ V       F C +  +  P + WF    +I  + N K  +   GNH  L I 
Sbjct: 4812 VKPIRDQHVKPKGTAIFACDIA-KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIK 4870

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            N    D          K     +  +L + E+E     + ++    + + E E    +A 
Sbjct: 4871 NAMPEDIAEYAVEIEGKR----YPAKLTLGEREV----ELLKPIEDVTIYEKESASFDAE 4922

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
                  P   W+  G  + P+P   I  +GG   L + + K   A
Sbjct: 4923 ISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLRKVKLDQA 4966



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 4/123 (3%)

Query: 1663 TSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRV 1722
            TS   ++ S+   +     E  L  ++Q++   K    +AQ +V+   P FT+ + D   
Sbjct: 5118 TSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTA 5177

Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782
             E      +  +       + V+W ++G  I  S + +   D     L +K  + +D G 
Sbjct: 5178 VEKDEITLKCEV----SKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGE 5233

Query: 1783 YTC 1785
            Y C
Sbjct: 5234 YVC 5236



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 3/79 (3%)

Query: 635  PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            PP +F  PL+  T  EG     E     V     K++W KNG  I  S ++  +      
Sbjct: 5786 PPVEFTKPLEDQTVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVR 5842

Query: 695  SLDMLSLNIQDSGEYTCRA 713
             L +     +D   YTC A
Sbjct: 5843 KLVIHDCTPEDIKTYTCDA 5861



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/98 (25%), Positives = 39/98 (39%), Gaps = 2/98 (2%)

Query: 766  TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
            T + P+    ++ L  L        E   T    P  ++ W K    +    RIT I N 
Sbjct: 7187 TQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRIT-IENV 7245

Query: 826  GYVS-LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               S + I+  +  D G+Y + AVN  G A +   + V
Sbjct: 7246 PKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 1584  LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSC 1642
             ++ + +K G    F   +  V   T K  W  +   +K+   +T ET+NF  V L I +C
Sbjct: 11020 IEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11076

Query: 1643  LPEDSGTYTCRAINALG 1659
             L  D+G Y     NA G
Sbjct: 11077 LRRDTGEYQITVSNAAG 11093



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/66 (28%), Positives = 28/66 (42%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P   + W K+G+ +    R+  I +   V L I      D G Y + A N  G A  +A 
Sbjct: 11439 PEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAI 11498

Query: 860   IRVAAR 865
             + V  R
Sbjct: 11499 VNVLDR 11504



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/64 (34%), Positives = 27/64 (42%)

Query: 3591  VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             + W   GK L+   RV  I D   V L+I    + D G Y   A N  G A  S  + V 
Sbjct: 11443 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVL 11502

Query: 3651  GRQG 3654
              R G
Sbjct: 11503 DRPG 11506



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             +    +K  +++K G     +A +   G     V W KDG  ++ +  I          L
Sbjct: 12799 DLSVAMKSLLTVKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTL 12856

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
              + SV   D+G YT  A N+ G  + +  L ++ K
Sbjct: 12857 ELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
             V  G     D  V G+P P V+W  +   ++     K+ + +     L + +V   DSG 
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVNRKDSGD 12868

Query: 463   VTCVARNKSGETAFQCRLNVIEK 485
              T  A N SG  +   +L V++K
Sbjct: 12869 YTITAENSSGSKSATIKLKVLDK 12891



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 6/105 (5%)

Query: 383   IEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
             +EI E+ +AP F    + R    V  G   R    + GRP PEVTW  ++  +++  N  
Sbjct: 14268 VEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRAN-- 14325

Query: 440   ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
              + N      L+I      D+G       N +G+ +    + V++
Sbjct: 14326 -IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLD 14369



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/114 (19%), Positives = 56/114 (49%), Gaps = 5/114 (4%)

Query: 4692  DYKCVAYNSAGRVTVAAKLK--VTQPD--QADNLPALTPLRDIVVYE-GQPAQFKTQITS 4746
             +++ +A N+AG ++  ++    +T  D  +A  +      +D V+ + G+  + +  ++ 
Sbjct: 14931 EFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSG 14990

Query: 4747  KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +  PT++W ++G  +  T   ++     +  L+  ++   D+G +T  AT   G
Sbjct: 14991 RPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15044



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 17/82 (20%), Positives = 35/82 (42%)

Query: 4732  VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             V  G+  +       +  P + W ++   + +T         NN++L I +   ED G +
Sbjct: 15662 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15721

Query: 4792  TCRATTAAGQVETSAKLVVKSK 4813
               + T +AG+   +  ++V  K
Sbjct: 15722 VVKLTNSAGEAIETLNVIVLDK 15743



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/55 (36%), Positives = 24/55 (43%)

Query: 2803  PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSA 2857
             PT  + W  +N PL   TR  +    +   L I     ED G Y  K TNS G A
Sbjct: 15678 PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 2/73 (2%)

Query: 2788  GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
             G ++  E  +     PT  I W  +  PL   TR   T      +L I  T+++D G Y 
Sbjct: 16747 GQDLKIEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYG 16804

Query: 2848  CKATNSKGSATTS 2860
                 N  G  T S
Sbjct: 16805 ITVANVVGQKTAS 16817



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 2/88 (2%)

Query: 1185  NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244
             N   +  G+++ +E  +  +G P   + W  +G  +   +R           L I     
Sbjct: 17822 NTYSIQAGEDLKIE--IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNK 17879

Query: 1245  ADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
              D G+YTV A N  G+A  +  V V+E+
Sbjct: 17880 DDFGKYTVTATNSAGTATENLSVIVLEK 17907



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 2/75 (2%)

Query: 3157  NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             N   ++ G+    E  V+    P+  I W  +G+P++ +TR+         VL I     
Sbjct: 17822 NTYSIQAGEDLKIEIPVIGRPRPN--ISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNK 17879

Query: 3217  HDSGEYVCRAYNKYG 3231
              D G+Y   A N  G
Sbjct: 17880 DDFGKYTVTATNSAG 17894



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 17/65 (26%), Positives = 29/65 (44%)

Query: 1738  GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
             G P+  V W ++G  ++ + R+         +L++K  + ED GTY     N  G     
Sbjct: 18923 GRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 18982

Query: 1798  STLFV 1802
              T+ V
Sbjct: 18983 ITIIV 18987



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 3/103 (2%)

Query: 3042  DDTGRPPEFTTV-FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
             DD   P     V F+D++ +  G++    A +   G    VI W  +G  IE   R   +
Sbjct: 19285 DDVEPPRVMMDVKFRDVIVVKAGEVLKINADI--AGRPLPVISWAKDGIEIEERARTEII 19342

Query: 3101  YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
                   +L +      D+G Y     N  G   ++V  + +DK
Sbjct: 19343 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 4/86 (4%)

Query: 4627  EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
             E  K  IV  G +   +    G+P+P V W K D  ++   Y  +  T    +L I  A 
Sbjct: 19694 EMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENAN 19751

Query: 4687  PEDEGDYKCVAYN--SAGRVTVAAKL 4710
               D G Y     N  SA  +T+  K+
Sbjct: 19752 RNDSGKYTLTIQNVLSAASLTLVVKV 19777



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 6/70 (8%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ--TGDVSLLIKQIGPGDEGE 143
             G N K +  + G P P V+ +R   PL    K +MR+N +    ++++ +K+    D G 
Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPL----KATMRFNTEITAENLTINLKESVTADAGR 20049

Query: 144   YTCTARNQYG 153
             Y  TA N  G
Sbjct: 20050 YEITAANSSG 20059



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 918   QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
             Q++++ G   H E   +  G     + WLKDG P++ S  +        + L+IK+    
Sbjct: 21075 QVTVRIGHNVHLELPYK--GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKE 21132

Query: 978   DAGHYTCRAYNAIGQATTSANLTIVT 1003
               G YT    NA+     +  +T++T
Sbjct: 21133 HGGKYTVILDNAV--CRIAVPITVIT 21156



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/63 (31%), Positives = 27/63 (42%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P  RV W+KDG  I     +      G  SL +     +  G YTV A N  G A +   
Sbjct: 21489 PVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIK 21548

Query: 860   IRV 862
             ++V
Sbjct: 21549 VKV 21551



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 4521  QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ- 4579
             + V + +G  +RL   V+G  P  + W K G  +       I++   +Y+LLI++   + 
Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL---ASRAIIDTTESYSLLIVDKVNRY 23013

Query: 4580  DSGKYECVAINSAGE 4594
             D+GKY   A N +G+
Sbjct: 23014 DAGKYTIEAENQSGK 23028



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/88 (23%), Positives = 34/88 (38%)

Query: 4726  PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             P + I V  G+P +    I  +  P   W   G+ + E+    +      A L I  T  
Sbjct: 23247 PQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTI 23306

Query: 4786  EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              DTG +T       G    + K+++  K
Sbjct: 23307 RDTGEYTLELKNVTGTTSETIKVIILDK 23334



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            + + P F   +Q V  L EG +A FEA +     P+  V WF +G+ +           F
Sbjct: 2    TTQAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISF 58

Query: 3338 --GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              G   L I    + NSG Y   ATN  G+ ++ A L
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/123 (21%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            +++ ++ T  P FV R +S+  V +G  V  + ++  +    +K  ++++G  +     F
Sbjct: 94   ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDF 150

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEAGL 1552
            +   +    +L I +   EDSG Y+  A N VG    +  L  +   ++  + T+     
Sbjct: 151  QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVST 210

Query: 1553 EQI 1555
             QI
Sbjct: 211  AQI 213



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADT 1247
            + EG  +   C++   G P  ++ W+ +G+ +  G R++  +   G  +L I      D 
Sbjct: 1256 ILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDE 1313

Query: 1248 GEYTVRAVNHLGSA 1261
            G YT  A N  G+A
Sbjct: 1314 GIYTAFASNIKGNA 1327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P  I Q   + K+ EG   Q +V++S      V W K+GQ +  S++  I+       L 
Sbjct: 2309 PIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLL 2367

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            + +  K D+G+Y+     P   + TSG ++V S
Sbjct: 2368 IEDMTKEDAGNYSFTI--PALGLSTSGRVSVYS 2398



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I +  P+   PL +     EG  +HL   +    +    V W+   + V    +FK   D
Sbjct: 4238 IKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQD 4292

Query: 1232 FGFVALDIIHATSAD-TGEYTVRAVNHLGSAHTSAIVRVIERS 1273
                 L I    + D  GEY   A+N  G   TSA + V++R+
Sbjct: 4293 QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 1445 RFVTRPKSI---ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            +FV   K I   E+   G    FEC + P   S     W K+G  +    + R I D   
Sbjct: 4619 KFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKD 4675

Query: 1502 VALDIIDLIAEDSGIYTC 1519
              L IID+   D+G YTC
Sbjct: 4676 RKLHIIDVQLSDAGEYTC 4693



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            FT PL + + + EG  A  E  ++     N KV+W+ NG  +    ++    D     L 
Sbjct: 5790 FTKPLED-QTVEEGATAVLECEVSRE---NAKVKWFKNGTEILKSKKYEIVADGRVRKLV 5845

Query: 3482 ISPTYPEDSGEYLCRA 3497
            I    PED   Y C A
Sbjct: 5846 IHDCTPEDIKTYTCDA 5861



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 771  QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSL 830
            +F+RPL DL +++E   A FE +L   S    +V+W+KDG  I    +   I       L
Sbjct: 5878 EFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGAVRIL 5933

Query: 831  NIMHLRAEDAGSYT 844
             I     +D   Y+
Sbjct: 5934 VINKCLLDDEAEYS 5947



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 29/56 (51%)

Query: 287  VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            V  +G PRP  TW    + L   ++ ++ T   +  L +  +++SD G YTL  EN
Sbjct: 6919 VPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLEN 6974



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 2/93 (2%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            KP       +  V EG  + +      V  PT  V W+ +G+ V+   R     D     
Sbjct: 7889 KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAH 7946

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L++  +   D G Y     N +G A  + +VKV
Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATASINVKV 7979



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 6/95 (6%)

Query: 69    PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
             PS  +  ++ +      G   +F   +RG P P   WT   + +    K    Y  +T +
Sbjct: 11011 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEI----KTDEHYTVETDN 11066

Query: 129   VS--LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              S  L IK     D GEY  T  N  G    +V++
Sbjct: 11067 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHL 11101



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 2/91 (2%)

Query: 912   KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTI 971
             K  + +QI+IK G     EA +   G      +W K    V  SS +          L I
Sbjct: 12404 KILMPEQITIKAGKKLRIEAHV--YGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12461

Query: 972   KSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             K VT  D+G+Y+  A N+ G  T    + ++
Sbjct: 12462 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVM 12492



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 7/119 (5%)

Query: 4689  DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQ 4743
             +E  ++ +A NSAGR        V   +Q   LP L  LR I     +   G   + +  
Sbjct: 14534 EEYTFQVMAVNSAGRSAPRESRPVIVKEQT-MLPELD-LRGIYQKLVIAKAGDNIKVEIP 14591

Query: 4744  ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
             +  + KPT+ W +   ++ +T          + +L I      D+G +   A    G+V
Sbjct: 14592 VLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEV 14650



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 2651  YDKLV---EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             Y KLV    G ++ +E  V  R  P   + W K    L    R+          L+IN  
Sbjct: 14574 YQKLVIAKAGDNIKVEIPVLGRPKPT--VTWKKGDQILKQTQRVNFETTATSTILNINEC 14631

Query: 2708  RNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                DSG Y   A N++GE     +I++ D
Sbjct: 14632 VRSDSGPYPLTARNIVGEVGDVITIQVHD 14660



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 5/124 (4%)

Query: 4692  DYKCVAYNSAGRVTVAAKLK--VTQPDQAD--NLPALTPLRD-IVVYEGQPAQFKTQITS 4746
             +++ +A N+AG  +  ++    +T  D+ D   +      +D IVV+ G+  +    I  
Sbjct: 16013 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 16072

Query: 4747  KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
             K  PTIQW++    +  T   ++        L + +    D+G +  +A   AG+   + 
Sbjct: 16073 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 16132

Query: 4807  KLVV 4810
              + V
Sbjct: 16133 NVKV 16136



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/83 (21%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
             V  G+  + D  + G+P P + W   D+++ +    +I   +    +L + +    DSG 
Sbjct: 16058 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT-SLSVKDAVRVDSGN 16116

Query: 463   VTCVARNKSGETAFQCRLNVIEK 485
                 A+N +GE +    + V+++
Sbjct: 16117 YILKAKNVAGERSVTVNVKVLDR 16139



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1974  VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
             +V +P       +  V  G  + +E  ++    PT  + W  +G P++Q  R   T    
Sbjct: 16729 LVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLD 16786

Query: 2034  YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L I   + +D G Y     N VG+   T+S+++
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQ--KTASIEI 16820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 3716  DCRVE-PV-GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT 3773
             D ++E P+ G P   I W  +G P    +R++  +      L I   +  D G+Y     
Sbjct: 16749 DLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVA 16808

Query: 3774  NKWGSATTTAKITCSAKRD 3792
             N  G  T + +I    K D
Sbjct: 16809 NVVGQKTASIEIVTLDKPD 16827



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/105 (21%), Positives = 45/105 (42%), Gaps = 4/105 (3%)

Query: 1301  VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
             + +D+T+  + +     ++I+  E     L+  +  +G     + W  +G+P+K   R  
Sbjct: 17807 IAKDLTIQPSLKLPFNTYSIQAGED----LKIEIPVIGRPRPNISWVKDGEPLKQTTRVN 17862

Query: 1361  PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                      L +     +D G YT  ATN  G A  + ++ V+ K
Sbjct: 17863 VEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 5/94 (5%)

Query: 483   IEKEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539
             I KE+   P F    E   TL V+ G    +     G P P + W K    +       +
Sbjct: 19679 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYV 19736

Query: 540   HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
              T    ++L I  A  +D+  Y  T QNV  + +
Sbjct: 19737 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAAS 19770



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/85 (24%), Positives = 35/85 (41%)

Query: 494   VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
             +E    +  R G  V L A   G P P I W KD   +  N  + +      +++ I  A
Sbjct: 20379 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20438

Query: 554   KASDAAWYQCTAQNVAGSTATRARL 578
                ++  Y+   +N  GS +   R+
Sbjct: 20439 DRLNSGCYELKLRNAMGSASATIRV 20463



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 1855  KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
             K   G S      I   P P   +EWY + K LQ+       N    A++ I      +S
Sbjct: 20386 KYRAGTSVKLRAGISGKPAPT--IEWYKDDKELQTNALVCVENTTDLASILIKDADRLNS 20443

Query: 1915  GEYTCKAINNLGQAVSSIRLNVQSK 1939
             G Y  K  N +G A ++IR+ +  K
Sbjct: 20444 GCYELKLRNAMGSASATIRVQILDK 20468



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/70 (25%), Positives = 30/70 (42%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  +  + F G P P + W ++   + +   + I    + S+L I QV   D+  +    
Sbjct: 20790 EDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTI 20849

Query: 4486  ENRGGTAKCS 4495
             EN  G  K S
Sbjct: 20850 ENGVGEPKSS 20859



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 6/109 (5%)

Query: 1701  SAQDEVIT-QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
             + ++ +IT +  +  +P   + V      H E  L   G PK  + WL++G+P++ S  +
Sbjct: 21056 TVKELIITPEVDLSDIPGAQVTVRIGHNVHLE--LPYKGKPKPSISWLKDGLPLKESEFV 21113

Query: 1760  TTMHDFGYVALNMKYVNPEDSGTYTC---RAINELGEAVTSSTLFVQSK 1805
                     + L++K    E  G YT     A+  +   +T  TL   SK
Sbjct: 21114 RFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSK 21162



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 2/61 (3%)

Query: 785   GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
             G N H E  L     P   + W KDG P+  S  +        ++L+I + + E  G YT
Sbjct: 21081 GHNVHLE--LPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21138

Query: 845   V 845
             V
Sbjct: 21139 V 21139



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/75 (26%), Positives = 31/75 (41%)

Query: 499   TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             T++V  G PV L     G P P  +W   G  +  +  + + T    + L I      D 
Sbjct: 23250 TIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 23309

Query: 559   AWYQCTAQNVAGSTA 573
               Y    +NV G+T+
Sbjct: 23310 GEYTLELKNVTGTTS 23324



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
             V +G + R    + G+P+P   W    +    D + + ++  S  H  L+I      DSG
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQ----DISKRAMIATSETHTELVIKEADRGDSG 23706

Query: 462   VVTCVARNKSGETAFQCRLNVI 483
                 V  NK G+ A   ++ VI
Sbjct: 23707 TYDLVLENKCGKKAVYIKVRVI 23728



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             R  +   G+P P+ KW +E   I  S    I T  T + L+I++    DS  +  V EN+
Sbjct: 23658 RLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENK 23715

Query: 4489  GG 4490
              G
Sbjct: 23716 CG 23717



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 2403  VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHV-RDEDEGVYMCRASNLLG 2458
             +G P   + WF  +KL+++S  IT  +   Y  + + +V R    G Y  + SN+ G
Sbjct: 24156 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG 24212



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 1444  PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
             PR   R +S   V  GQ+  F   ++  +    +V+W+ NG  +    +    +  G + 
Sbjct: 25877 PRITLRMRS-HRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 25933

Query: 1504  LDIIDLIAEDSGIYTCRAVNLVG 1526
             L+I+D   +DSG Y     N  G
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKG 25956



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/74 (27%), Positives = 30/74 (40%)

Query: 4003  PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAV 4062
             P  +V+W+ NG  L   ++       G + +     + +DSG Y    TN  G     A 
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYAT 25963

Query: 4063  IKTTGKPGIVYDSQ 4076
             +  TG     Y SQ
Sbjct: 25964 LDVTGGDYTTYASQ 25977



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 8/119 (6%)

Query: 4700 SAGRVTVAAKLKVTQPDQADNL--PA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            S  R++   +L+ T   Q + L  P   L P+      EGQ A+F  ++  +  P   W 
Sbjct: 1387 SPARMSPGRRLEETDESQLERLYKPVFVLKPV-SFKCLEGQTARFDLKVVGRPMPETFWF 1445

Query: 4756 REGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +G  I      +++   +G  +++++  T   D+G +T  A   AG+   S  L V++
Sbjct: 1446 HDGQQIVNDYTHKVVIKEDGTQSLIIVPAT-PSDSGEWTVVAQNRAGRSSISVILTVEA 1503



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 774  RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIM 833
            +PL D   + E + A FE +   V++P  + EW +DG+ +  ++ I S  +     L I 
Sbjct: 2578 KPLTDQ-TVAESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIA 2633

Query: 834  HLRAEDAGSYTVR-AVNKLGEAISTASIRV 862
              + +D G YT + A +K    +   ++++
Sbjct: 2634 ATKLDDIGEYTYKVATSKTSAKLKVEAVKI 2663



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 2245 VTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDI 2304
            +T+      V E KTA FEC+V   + P++ ++   NG  ++ + +F I        L I
Sbjct: 2838 ITKTMKNIEVPETKTASFECEVSHFNVPSMWLK---NGVEIEMSEKFKIVVQGKLHQLII 2894

Query: 2305 QHCVPEDAGEYS 2316
             +   ED+ EY+
Sbjct: 2895 MNTSTEDSAEYT 2906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/64 (29%), Positives = 31/64 (48%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P+++ +WF  G+++    +        I  L+IL     + GEY C A+N+ G  S  A 
Sbjct: 4364 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 4423

Query: 3372 LKCT 3375
            L  T
Sbjct: 4424 LTVT 4427



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 10/100 (10%)

Query: 3691 KPNPPRFTVEIKDNIDVPE---GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            K  P +F  EIKD I       G    F+C V P    T    W  +G       +   +
Sbjct: 4614 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFI 4670

Query: 3748 NDFGFIALDIDYIYARDAGEYTC--RATNKWGSATTTAKI 3785
             D     L I  +   DAGEYTC  R  NK    T+TAK+
Sbjct: 4671 ADGKDRKLHIIDVQLSDAGEYTCVLRLGNK--EKTSTAKL 4708



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 910  EFKTPIKDQISIKE---GGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            +F   IKD I  +    G  A FE  + P   ST    W+KDG  +  S +     +   
Sbjct: 4619 KFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKD 4675

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              L I  V + DAG YTC       + T++A L +
Sbjct: 4676 RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV 4710



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%)

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
            G SA FE  V P + +T    W  +G  I  + + +   D     L I  V+  D+G YT
Sbjct: 4636 GSSAIFECLVSPSTAITT---WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 4692

Query: 1118 VVARNAAGEAQLSASMTVE 1136
             V R    E   +A + VE
Sbjct: 4693 CVLRLGNKEKTSTAKLVVE 4711



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 3/81 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L +   +EG     EC V  SR+   K++WF N   +    +Y+   D     L I
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV--SRE-NAKVKWFKNGTEILKSKKYEIVADGRVRKLVI 5846

Query: 2836 THTYEEDSGIYTCKATNSKGS 2856
                 ED   YTC A + K S
Sbjct: 5847 HDCTPEDIKTYTCDAKDFKTS 5867



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 16/135 (11%)

Query: 1824 LEDSSRYQ-----RREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMR 1877
            LED+  Y       R D +V V++ A  FI++     ++ EG+ A + C I     P   
Sbjct: 6029 LEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQN-LEILEGEKAEFVCSISKESFP--- 6084

Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY-----TCKAINNLGQAVSSI 1932
            V+W  + K L+SG +Y    D     L +     +D G Y       +A  +L   +  +
Sbjct: 6085 VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHL-TVIEKL 6143

Query: 1933 RLNVQSKESIIRDSQ 1947
            R+ V  K++ +++ Q
Sbjct: 6144 RIVVPLKDTRVKEQQ 6158



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 16/180 (8%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            ++I EG+ A +  S+     +S  ++W  + KT+E+  +   +      VL +      D
Sbjct: 6064 LEILEGEKAEFVCSI---SKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQD 6120

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             GTY        G A  +  L  ++K +   P   T +      K+ Q   F C    V+
Sbjct: 6121 MGTYVVMV----GAARAAAHLTVIEKLRIVVPLKDTRV------KEQQEVVFNC---EVN 6167

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
                K +W+ N + +  S++   +       L I      D   Y     N  GE+   A
Sbjct: 6168 TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSA 6227



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 52/267 (19%), Positives = 101/267 (37%), Gaps = 22/267 (8%)

Query: 4371 EVVGDKEITRKITSTETTEIEHKAQTQERV-VEGPVKPSKPPIFTKKMQPCRVFEHEQAR 4429
            +V+   E+  ++ +     + H ++  E + +E P  P  PP+        R  +H    
Sbjct: 7750 DVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIA 7807

Query: 4430 FEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVFVEDSAVFAAV-AEN 4487
            ++        P+I ++ E  P+      ++++   K +   + +  V D      V A N
Sbjct: 7808 WKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVN 7867

Query: 4488 RGGTAK---CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
              G ++    S N+V ++   +       P+  L   ++ V  G+ + +           
Sbjct: 7868 AIGVSEPSEISENVVAKDPDCK-------PTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 7920

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VV 4603
            V W K+GK+V+   R  +  +  +  L + ++   D+G Y     N  G A       V+
Sbjct: 7921 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 7980

Query: 4604 SLPA------TKDKPKPQTKAANAPPE 4624
             LP         D  K   K    PPE
Sbjct: 7981 GLPGPCKDIKASDITKSSCKLTWEPPE 8007



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            ++EG+ L +   V  +  P   + W+ +GK ++   R  + +D     L++      D+G
Sbjct: 7901 VIEGEKLSIP--VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAG 7958

Query: 2983 IYTCKAYNKRGEAFTSSTV 3001
            IYT    NK G A  S  V
Sbjct: 7959 IYTITLENKLGSATASINV 7977



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/61 (31%), Positives = 28/61 (45%)

Query: 3454 VEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            V W+ +GK +KA  R     D     LE+  +   D+G Y     N  G A  + ++KV 
Sbjct: 7921 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 7980

Query: 3514 G 3514
            G
Sbjct: 7981 G 7981



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/71 (23%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 232  REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
            +E  FR    +   G S+   +T   +++ P+  PK+  +  + +++ G +      +SG
Sbjct: 8151 KEYQFRVR-AENAAGISEPSRATPPTKAVDPIDAPKVILRT-SLEVKRGDEIALDASISG 8208

Query: 292  NPRPRVTWFKN 302
            +P P +TW K+
Sbjct: 8209 SPYPTITWIKD 8219



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/93 (25%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 3423  TVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI 3482
             +V + ++  ++ G N   +A  T    P   V W  +G  LK     +         LE+
Sbjct: 12801 SVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 12858

Query: 3483  SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
                  +DSG+Y   A N+ G    T  +KV  K
Sbjct: 12859 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/91 (24%), Positives = 38/91 (41%), Gaps = 2/91 (2%)

Query: 2916  PIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVD 2975
             P  + + +  GQ L +E  +  +  P   I W  +G  L+Q +R  +T      TL + +
Sbjct: 16737 PAFSSYSVQVGQDLKIEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLDLTTLSIKE 16794

Query: 2976  VYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
              ++ D G Y     N  G+   S  +    K
Sbjct: 16795 THKDDGGQYGITVANVVGQKTASIEIVTLDK 16825



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 637   PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
             P   +P  + +   G  +  E  I  +G P   I W+K+G+ ++ ++R           L
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIE--IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVL 17872

Query: 697   DMLSLNIQDSGEYTCRAVSATGVA 720
              +   N  D G+YT  A ++ G A
Sbjct: 17873 HIKEGNKDDFGKYTVTATNSAGTA 17896



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/77 (27%), Positives = 32/77 (41%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P   V W KDG+ +  ++R+    +    SL+I     ED G+Y +   N  G      +
Sbjct: 18925 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPIT 18984

Query: 860   IRVAARSTVTADLGIPE 876
             I V  R      + I E
Sbjct: 18985 IIVLDRPGPPGPIRIDE 19001



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/62 (24%), Positives = 30/62 (48%)

Query: 943   VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             V W KDG+ ++ ++R+    +    +L+IK  +  D G Y     N+ G  T    + ++
Sbjct: 18929 VNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVL 18988

Query: 1003  TK 1004
              +
Sbjct: 18989 DR 18990



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
             G N   E   +G P P +SW +   PL E     +R+++    ++L IK       G+YT
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESE--FVRFSKTENKITLSIKNAKKEHGGKYT 21138

Query: 146   CTARNQYGEAICSVYI 161
                 N    A+C + +
Sbjct: 21139 VILDN----AVCRIAV 21150



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 1832  RREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH 1891
             R E+V   V   P +   L     +  G+S   +  ++  P P  RV W+ +G  ++   
Sbjct: 21453 RDENVPPIVEFGPEYFDGLI----IKSGESLRIKALVQGRPVP--RVTWFKDGVEIEKRM 21506

Query: 1892  RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
                 ++  G  +L +     +  G YT +A N  G A + I++ VQ
Sbjct: 21507 NMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/68 (29%), Positives = 30/68 (44%)

Query: 2007  PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
             P  RV W+ +G  +++    + T   G  +L +  A  +  G Y  +A NA G A     
Sbjct: 21489 PVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIK 21548

Query: 2067  VKVDAKSG 2074
             VKV    G
Sbjct: 21549 VKVQDTPG 21556



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/70 (25%), Positives = 28/70 (40%)

Query: 4431  EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
             +V   G P P + W  E   +K +    I T   ++ L ++     DS  +    EN  G
Sbjct: 22171 DVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 22230

Query: 4491  TAKCSANLVV 4500
                 S  +VV
Sbjct: 22231 VKTFSVTVVV 22240



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%)

Query: 2535  VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             VG P    +WY  G EL    +++ + D    TL + +    D G+Y C A N  G
Sbjct: 24060 VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 24115


>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
          Length = 26926

 Score =  293 bits (720), Expect = 8e-78
 Identities = 268/1028 (26%), Positives = 455/1028 (44%), Gaps = 98/1028 (9%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY---RTVYDMGF 3886
            P F+ ++K+  ++E  G R E +V    +P   I W +N  ++   H+Y   R     G 
Sbjct: 1510 PMFVEKLKNVNIKE--GSRLEMKVRATGNPNPDIVWLKNSDIIVP-HKYPKIRIEGTKGE 1566

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK---KLPDIILQNQVPRGMKRSE-- 3941
             +L I    ++DS  Y   A+N  G D T+  ++ +     P+   +  +PRG  R++  
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 3942 ALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVG 4001
            A  ++E    +Y  E +  E DLYD +K+Q P F  ++ S   L       FEC+L P+ 
Sbjct: 1627 AAPELEPLHLRYGQEQW-EEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPIS 1684

Query: 4002 DPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
            DP M VEW  +GKPL   NR   I +FGY ++++G  Y  DSG   CRATN YG D T A
Sbjct: 1685 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1744

Query: 4062 VIKTTGKPGIVYDSQLPKHMKSIEKIREMEA-SWQVTPEQVVEESKARCPPVFVSLPDAV 4120
             +    +  +V +SQLP+  K +++I E+E  + +     V  + K +  P  V  P+ V
Sbjct: 1745 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1804

Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGKI 4180
             V EGE ARF CRVTG+P+P+V W LNG  I    R+++ YDG+++ DI   + YDTG++
Sbjct: 1805 RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEV 1864

Query: 4181 EVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYD-ETTQYQRTETELEK------ 4233
            +V              L++  R +D+R VL+ AP P  +    +  + + E++K      
Sbjct: 1865 KVTAENPEGVIEHKVKLEIQQR-EDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVD 1923

Query: 4234 TFEERQV--LQRQGVIDHRP------ELKPKVIKEPETEWQQSV------KRKKNEEYYN 4279
            T E ++V  L+R   I H        EL+ K  +  E  + +++       RKK+E Y  
Sbjct: 1924 TTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEE 1983

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQT---EEVTEQR 4336
             L++ ++E +     L E   +      K+T  T      +    +++     E +  Q 
Sbjct: 1984 LLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIE-LSPSMEAPKIFERIQSQT 2042

Query: 4337 VQKKVTQKPRI-----PDPSESTVHGKEVHVAKQKQTQKEVVGDKE---ITRKITSTETT 4388
            V +      R+     PDP E   +   V + +  +       D     + R +T+ ++ 
Sbjct: 2043 VGQGSDAHFRVRVVGKPDP-ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSA 2101

Query: 4389 EIEHKAQTQERVVEGP----VKPSKPPIFTKKMQPCRVFEHE-QARFEVEFDGEPLPLIK 4443
             I  KA              V+  +   FT+++Q     E +  A FE E   EP   +K
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECE-TSEPFVKVK 2160

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            WY++   +     +++H+      L I  +   D+  ++ V        K +A L+VE  
Sbjct: 2161 WYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE-DENVKTTAKLIVE-- 2217

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                 G +V   F    Q++ V       L+  +   + I+  W  N  +++ + +  I 
Sbjct: 2218 -----GAVV--EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTIT 2269

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623
               G   L + +   +D G+Y  V      +  C           K K KP+      P 
Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTC-----------KLKMKPR------PI 2310

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
             I++ L D+ V EG  ++   K+  + +  V W K  + ++PS    +      + L I 
Sbjct: 2311 AILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIE 2369

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
            +   ED G+Y       A  ++ + ++ V   D       +TPL+D+ V EG  A  + +
Sbjct: 2370 DMTKEDAGNYSFTI--PALGLSTSGRVSVYSVD------VITPLKDVNVIEGTKAVLECK 2421

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            ++     +++W      I      Q I +G    L+I  T+  D G +        G+VE
Sbjct: 2422 VSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPY----KLIVGRVE 2477

Query: 4804 TSAKLVVK 4811
            T+  L V+
Sbjct: 2478 TNCNLSVE 2485



 Score =  253 bits (619), Expect = 1e-65
 Identities = 162/511 (31%), Positives = 247/511 (48%), Gaps = 14/511 (2%)

Query: 377  RETEERIEIS-EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            R  EE  E   E+   P FV         EG   RFD +V GRP PE  WF + +QI +D
Sbjct: 1395 RRLEETDESQLERLYKPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVND 1454

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
            Y HK+++ E G  +L+I   T SDSG  T VA+N++G ++    L V   E  V P FVE
Sbjct: 1455 YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514

Query: 496  RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN--PELRIHTDGGASTLDIPRA 553
            +   +N++EG  + +  RA G P P I W K+   I+P+  P++RI    G + L I   
Sbjct: 1515 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDST 1574

Query: 554  KASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXX 613
             + D+AWY  TA N AG   TR ++           +++L +PR T              
Sbjct: 1575 VSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPL 1634

Query: 614  YLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            +LR+ +         ++++    P F   L S+     G  HFE R+ P+ DPTM +EWL
Sbjct: 1635 HLRYGQEQWEEGDLYDKEK-QQKPFFKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEWL 1693

Query: 674  KNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             +G+ +EA++R   I  FGY SLD      +DSG  TCRA +  G   T A L V    +
Sbjct: 1694 HDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKS 1753

Query: 734  IERTSQHPETLQYIQQLEDYSKYQHQESI-----EEQTSQRPQFIRPLQDLGELQEGRNA 788
            +   SQ PE  + +Q++E+  +  H+ ++     +++  Q+P  +   + +  L EG  A
Sbjct: 1754 LVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVL-EGETA 1812

Query: 789  HFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAV 848
             F  ++T    P  +V WY +G+ I  S R    ++ G   L+I+  ++ D G   V A 
Sbjct: 1813 RFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAE 1869

Query: 849  NKLGEAISTASIRVAARSTVTADL-GIPEQR 878
            N  G       + +  R    + L   PE R
Sbjct: 1870 NPEGVIEHKVKLEIQQREDFRSVLRRAPEPR 1900



 Score =  185 bits (450), Expect = 4e-45
 Identities = 177/649 (27%), Positives = 283/649 (43%), Gaps = 60/649 (9%)

Query: 3293 KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT-FHDFGIVILDILYCYEEN 3351
            +++EG    F  ++     P  K+ W+ +GK++ HG RY+  F   G   L I     E+
Sbjct: 1255 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312

Query: 3352 SGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTS 3411
             G Y   A+N       K N  C+ K  L ++   P G       + TLE   V R  + 
Sbjct: 1313 EGIYTAFASN------IKGNAICSGK--LYVEPAAPLGAP---TYIPTLEP--VSRIRSL 1359

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTP------TDDPNL----KVEWYWNGK 3461
                  ++P+   P + +   R        AR++P      TD+  L    K  +     
Sbjct: 1360 SPRSVSRSPIRMSP-ARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV 1418

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            S K         D   V   +  T+    G+ +    N+Y   V    +K  G +++I+ 
Sbjct: 1419 SFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIV---NDYTHKVV---IKEDGTQSLIIV 1472

Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEA-ESGNPPEFTTTPSDLILSENSSAHFECR 3580
               P              G S     LT EA E    P F     ++ + E S    E +
Sbjct: 1473 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGS--RLEMK 1530

Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGS--RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
            +    + +  + W  N   ++     +++     G   L+I     +D+  YT  A N+ 
Sbjct: 1531 VRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1590

Query: 3639 GEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE----ETLHKR------EEITIE 3688
            G  T  CK+ V+  +    EP+       GT   +++     E LH R      EE  + 
Sbjct: 1591 GRDTTRCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649

Query: 3689 D-EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            D EK   P F  ++  ++ +   GP HF+CR+ P+ DPTM ++W H+G+P    +R+  +
Sbjct: 1650 DKEKQQKPFFKKKLT-SLRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMI 1708

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSG-E 3806
            N+FG+ +LD    Y+RD+G  TCRATNK+G+  T+A +    ++ +V ESQLP+G  G +
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQ 1768

Query: 3807 KIKELER----GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            +I+ELER    G ++    ++      P  +   +   V E E  RF CRV     PK  
Sbjct: 1769 RIEELERMAHEGALTGVTTDQK-EKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPK-- 1825

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            + WY NG+L+    R+R  YD G   LDI+   + D+GE    A N  G
Sbjct: 1826 VNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1873



 Score =  181 bits (441), Expect = 5e-44
 Identities = 218/822 (26%), Positives = 344/822 (41%), Gaps = 106/822 (12%)

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTN-KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
            R  +  E +++   KP F+  LK  + K +EG +  F+ +V  +  +  T  W+ +G+QI
Sbjct: 1396 RLEETDESQLERLYKPVFV--LKPVSFKCLEGANCRFDLKVVGRP-MPETF-WFHDGQQI 1451

Query: 1087 TS--ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTS 1144
             +   +++    D G  +L I      DSG +TVVA+N AG + +S  +TVE        
Sbjct: 1452 VNDYTHKVVIKED-GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA------- 1503

Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPM 1204
                        +E    V+PM+    + K K V ++         EG  +  E ++   
Sbjct: 1504 ------------VEHQ--VKPMF----VEKLKNVNIK---------EGSRL--EMKVRAT 1534

Query: 1205 GDPTMRVEWFHNGRSVTVGS--RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAH 1262
            G+P   + W  N   +      + +     G  AL I    S D+  YT  A+N  G   
Sbjct: 1535 GNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDT 1594

Query: 1263 TSAIVRV--------IERSDIV---TDTQNEQAIEQIQLLEDAARRTKQVREDI---TVM 1308
            T   V V         ER  I+   T    E A  +++ L     + +    D+      
Sbjct: 1595 TRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQ 1654

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P F + L ++        H ECRL P+ D TM VEW  +GKP++  +R R   EF Y 
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1714

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            +LD    Y  DSG+ TC+ATN+ G   TS  L V  +K L+ ESQ P G + +Q +E+  
Sbjct: 1715 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELE 1774

Query: 1429 RYKKTDII-----DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN 1483
            R      +     D+    KP  V  P+ +  V+EG+   F C++        KV W+ N
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLN 1831

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            GQ +    RFR  +D G   LDI+D  + D+G     A N  G  E   +L  +   D  
Sbjct: 1832 GQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF- 1889

Query: 1544 RSTQNEA--GLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKN-VEIKEGQRAHFERR 1600
            RS    A     +  V E          VD      P+ TT  K  V++K  +R   E+ 
Sbjct: 1890 RSVLRRAPEPRPEFHVHEPGKLQFEVQKVDR-----PVDTTETKEVVKLKRAERITHEK- 1943

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNF-GFVALDIMSCLPEDSGTYTCRAINALG 1659
             +P     L+ ++           R TE   +    A+++ S   ++S     R      
Sbjct: 1944 -VPEESEELRSKF----------KRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-- 1990

Query: 1660 EAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKD 1719
                    ++H  K   L  + + AL    ++     ++    +     +AP     ++ 
Sbjct: 1991 -------ELLHWTKE--LTEEEKKALAEEGKI-TIPTFKPDKIELSPSMEAPKIFERIQS 2040

Query: 1720 IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPE 1778
              V +   AHF  R+  VG P    EW +NGV IE S+R+        V  L ++ V  E
Sbjct: 2041 QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2098

Query: 1779 DSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
            DS +   +AIN  GE  + + L VQ+K  +    + +  + K
Sbjct: 2099 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2140



 Score =  172 bits (418), Expect = 3e-41
 Identities = 155/534 (29%), Positives = 233/534 (43%), Gaps = 64/534 (11%)

Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488
            R ++TD        KP FV +P S +  +EG +  F+ K+  V     +  WF +GQ + 
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFK-CLEGANCRFDLKV--VGRPMPETFWFHDGQQIV 1452

Query: 1489 IGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
              +  +  I + G  +L I+     DSG +T  A                         Q
Sbjct: 1453 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVA-------------------------Q 1487

Query: 1548 NEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEGQRAHFERRLIPVSD 1606
            N AG   I V+           V+ V  Q  P+    LKNV IKEG R   E ++    +
Sbjct: 1488 NRAGRSSISVILT---------VEAVEHQVKPMFVEKLKNVNIKEGSR--LEMKVRATGN 1536

Query: 1607 ATLKVEWYHNNKPLKSGS--RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                + W  N+  +      +       G  AL I S + +DS  YT  AIN  G   T 
Sbjct: 1537 PNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1596

Query: 1665 GIAIVH--------SKKSIYLESQH---EGALPRLNQLE---DTSKYQRHSAQDEVITQA 1710
                V          +K I     +   E A P L  L       +++     D+   Q 
Sbjct: 1597 CKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQK 1656

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +  +R+     AHFE RL P+ DP + VEWL +G P+EA+NRL  +++FGY +L
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1716

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
            +       DSG  TCRA N+ G   TS+TL V+ + SL  ESQ     + +Q++E+  R 
Sbjct: 1717 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1776

Query: 1831 QRREDVE-VAVNQAPR---FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                 +  V  +Q  +    I     P ++ EG++A + CR+  YP P  +V WY NG++
Sbjct: 1777 AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQL 1834

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++   R+R   D G   LDI+     D+GE    A N  G     ++L +Q +E
Sbjct: 1835 IRKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1887



 Score =  163 bits (395), Expect = 2e-38
 Identities = 131/455 (28%), Positives = 207/455 (45%), Gaps = 31/455 (6%)

Query: 3084 WFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            WF++G+ I  + +H++  +   G   L I+    +DSG ++  A N+ G++ ISV L   
Sbjct: 1444 WFHDGQQIVNDYTHKV-VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1502

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ---PMRHSTRI 3198
                  KP F   ++N+  +K+G  +  E  V    +P+  I W  N     P ++  +I
Sbjct: 1503 AVEHQVKPMFVEKLKNV-NIKEG--SRLEMKVRATGNPNPDIVWLKNSDIIVPHKY-PKI 1558

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINC---YGKGGVYLESLQPD 3255
            +     G   L I  T + DS  Y   A NK G D TR  +N    + +     + + P 
Sbjct: 1559 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPR 1618

Query: 3256 SLAKIRELES-------LQGAQQQTPSTPSAEPPK----FITQIQDVTKLVEGQSAHFEA 3304
               + +E+ +       L+  Q+Q       +  K    F  +     +L     AHFE 
Sbjct: 1619 GTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFEC 1678

Query: 3305 RLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            RL P+ DP + VEW ++GK L   +R R  ++FG   LD    Y  +SG   C ATNK G
Sbjct: 1679 RLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYG 1738

Query: 3365 RDSTKANLKCTSKENLILDSQLPRGMEG--GLEKLQTLEDSMVRRKDTSVEEEKGKAPVF 3422
             D T A L    +++L+ +SQLP G +G   +E+L+ +         T+ ++EK K  + 
Sbjct: 1739 TDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIV 1798

Query: 3423 TVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI 3482
              P      + EGE A F  R+T    P  KV WY NG+ ++   RFR   D G   L+I
Sbjct: 1799 LYP--EPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDI 1853

Query: 3483 SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
                  D+GE    A N  G       +++Q + +
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888



 Score =  162 bits (394), Expect = 2e-38
 Identities = 166/643 (25%), Positives = 271/643 (42%), Gaps = 50/643 (7%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSY--VS 2832
            +F+  L N+  KEG  +  E  V  + +P   I W  N+  +      K   + +    +
Sbjct: 1511 MFVEKLKNVNIKEGSRL--EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1568

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLE------- 2885
            L I  T  +DS  YT  A N  G  TT    RC  +  + F    P+ K  +        
Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTT----RCKVNVEVEFAEPEPERKLIIPRGTYRAK 1624

Query: 2886 --AVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKN 2939
              A  + E   L  G+        Y K +   P   +     +L      H E ++ P +
Sbjct: 1625 EIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIS 1684

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            DP + +EW  +GK LE  +R ++ ++FG+ +LD    Y RDSGI TC+A NK G   TS+
Sbjct: 1685 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1744

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKE--PGQQPDDDTGRPPEFTTVFKDI 3057
            T+    + +L+E +Q P+G +GL++I+ LE    +    G   D    + P+   ++ + 
Sbjct: 1745 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEP 1803

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V + EG+ A +   +  TG     + W+ NG+ I  S R R  Y  G+  L+I+  K+ D
Sbjct: 1804 VRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYD 1860

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKS-------KGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            +G     A N  G  E  VKLE   +        +  +PR   H+     L+      FE
Sbjct: 1861 TGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQ------FE 1914

Query: 3171 CTVV--PVDDPDMK-IEWYHNGQPMRHSTRIKTVSDFGFVV---LDIAYTQNHDSGEYVC 3224
               V  PVD  + K +      + + H    +   +         +  Y +   + E   
Sbjct: 1915 VQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKS 1974

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            R  ++  E+  R T +        L   +  +LA+  ++        +   +PS E PK 
Sbjct: 1975 RKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKI 2034

Query: 3285 ITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR-YRTFHDFGIVILD 3343
              +IQ  T + +G  AHF  R+V   DP+   EW+ NG K+    R Y  + +  +  L 
Sbjct: 2035 FERIQSQT-VGQGSDAHFRVRVVGKPDPE--CEWYKNGVKIERSDRIYWYWPEDNVCELV 2091

Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQL 3386
            I     E+S      A N  G  S+ A L   +K+ +    +L
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQEL 2134



 Score =  157 bits (381), Expect = 9e-37
 Identities = 120/421 (28%), Positives = 194/421 (46%), Gaps = 33/421 (7%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV--QQGHRFKTTYDFGY 2034
            KP F + +KN  + EG    LE  +    +P   + W  N   +   +  + +     G 
Sbjct: 1509 KPMFVEKLKNVNIKEGS--RLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE 1566

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG------LYLDTLDEQRLKKI 2088
             AL I    ++D+  Y   A N  G   T   V V+ +          +      R K+I
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 2089 Q--ELE----KYERPK----PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPIND 2138
               ELE    +Y + +     + +++  Q+P F   LTSL  LK    AHFECR+ PI+D
Sbjct: 1627 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLR-LKRFGPAHFECRLTPISD 1685

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P + ++W H+G+ + A +R R  ++FGY +LD    Y+ DSG   C+ATNK G    + T
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745

Query: 2199 LKVAGHRNIILDTQHP---NGLEKIRQLEAQGHS---TRIEVEEPKISPPRFVTELRGTT 2252
            L V   ++++ ++Q P    GL++I +LE   H    T +  ++ +   P  V       
Sbjct: 1746 LIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVL-YPEPV 1804

Query: 2253 HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDA 2312
             V EG+TA F C+V     P  ++ +Y NG+ ++ + RF + +D G   LDI  C   D 
Sbjct: 1805 RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1861

Query: 2313 GEYSVKAINALGHCTSAISMTVTAKGSIISESQR-PEGLEKIRELESAE-PFKRPEIPEP 2370
            GE  V A N  G     + + +  +    S  +R PE   +    E  +  F+  ++  P
Sbjct: 1862 GEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRP 1921

Query: 2371 V 2371
            V
Sbjct: 1922 V 1922



 Score =  157 bits (380), Expect = 1e-36
 Identities = 187/749 (24%), Positives = 305/749 (40%), Gaps = 59/749 (7%)

Query: 3346 YCYEENSGEYE---CVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKL--- 3397
            + Y E   EYE    +   K+ +D+         +E  I   + +L + +E  + K    
Sbjct: 1163 FVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLE 1222

Query: 3398 QTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWY 3457
            + LE+    +    + E +     F + + N   L EG    F  +++    P  K+ WY
Sbjct: 1223 ELLEEDGEEKMAVDISESEAVESGFDLRIKNYRIL-EGMGVTFHCKMSGYPLP--KIAWY 1279

Query: 3458 WNGKSLKAGSRFR-TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
             +GK +K G R++  F   G   L I    PED G Y   A N  G A+ +  + V+   
Sbjct: 1280 KDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE--- 1336

Query: 3517 NIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFT---TTPSDLILSENS 3573
                    P    G    I  LE  S  + +L+P + S +P   +    +P+ +  +  S
Sbjct: 1337 --------PAAPLGAPTYIPTLEPVS-RIRSLSPRSVSRSPIRMSPARMSPARMSPARMS 1387

Query: 3574 SAHFE-CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYT 3631
             A     R +   D S ++E  +    +L     K +        L++ G    +   + 
Sbjct: 1388 PARMSPGRRLEETDES-QLERLYKPVFVLKPVSFKCLEGANCRFDLKVVGRPMPET-FWF 1445

Query: 3632 CKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIED-E 3690
                    + T    ++  G Q +I+ P  PS     T   Q           +T+E  E
Sbjct: 1446 HDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505

Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLN 3748
                P F  ++K N+++ EG     + +V   G+P   I W  N          ++    
Sbjct: 1506 HQVKPMFVEKLK-NVNIKEGS--RLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562

Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS---AKRDIVLESQLPQGMSG 3805
              G  AL ID   ++D+  YT  A NK G  TT  K+      A+ +   +  +P+G   
Sbjct: 1563 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYR 1622

Query: 3806 EK---IKELE--RGRISDAPKEEPIV-----STPPKFITQIKSHTVEESEGVRFECRVEP 3855
             K     ELE    R      EE  +        P F  ++ S  ++      FECR+ P
Sbjct: 1623 AKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTP 1682

Query: 3856 KEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT 3915
              DP + +EW  +GK L + +R R + + G+ SLD    Y+ DSG   CRA N +G D T
Sbjct: 1683 ISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHT 1742

Query: 3916 KATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRF 3975
             AT+  K    ++ ++Q+P G K  + + ++E    +   E  LT     D  +KQ P  
Sbjct: 1743 SATLIVKDEKSLVEESQLPEGRKGLQRIEELE----RMAHEGALT-GVTTDQKEKQKPDI 1797

Query: 3976 VTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNF 4035
            V        ++E ET +F C++   G P  KV W+ NG+ +    RF   YD G   ++ 
Sbjct: 1798 VL-YPEPVRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDI 1853

Query: 4036 GWVYPEDSGEYLCRATNLYGMDETKAVIK 4064
                  D+GE    A N  G+ E K  ++
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLE 1882



 Score =  150 bits (364), Expect = 1e-34
 Identities = 171/672 (25%), Positives = 279/672 (41%), Gaps = 59/672 (8%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASS-- 817
            E++E Q   +P F+  L+++  ++EG  +  E ++    +P   + W K+   I      
Sbjct: 1502 EAVEHQV--KPMFVEKLKNVN-IKEG--SRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP 1556

Query: 818  RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA---ARSTVTADLGI 874
            +I      G  +L I    ++D+  YT  A+NK G   +   + V    A       L I
Sbjct: 1557 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1616

Query: 875  PE---QRRYI---EKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
            P    + + I   E                     E  QKP FK  +   + +K  G AH
Sbjct: 1617 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAH 1675

Query: 929  FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
            FE RL PI D T+ VEWL DG+P+EA++R+     FGY +L        D+G  TCRA N
Sbjct: 1676 FECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1735

Query: 989  AIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKR-----TEEEVKITQKP 1043
              G   TSA L +  +K ++ ESQ P G + +Q +E+  R +          + K  QKP
Sbjct: 1736 KYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKP 1795

Query: 1044 RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVAL 1103
              +       +++EG++A F  RV         V WY NG+ I  + R +  +D G   L
Sbjct: 1796 DIV-LYPEPVRVLEGETARFRCRVTGYPQ--PKVNWYLNGQLIRKSKRFRVRYD-GIHYL 1851

Query: 1104 DIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFV 1163
            DI   ++ D+G   V A N  G  +    + ++ R   D  S+ R   E           
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE--DFRSVLRRAPEP---------- 1899

Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223
             P + + E  K +   VQ +  P   +E K +    R E +    +  E      S  + 
Sbjct: 1900 RPEFHVHEPGKLQ-FEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEE------SEELR 1952

Query: 1224 SRFKTYYDFGFV-ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
            S+FK   + G+  A+  +   S    E     +             ++  +  +T+ + +
Sbjct: 1953 SKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKD-------ELLHWTKELTEEEKK 2005

Query: 1283 QAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTM 1342
               E+ ++     +  K   E    M+AP+    + +    +G++ H   R++ VG    
Sbjct: 2006 ALAEEGKITIPTFKPDK--IELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRVVGKPDP 2061

Query: 1343 RVEWFCNGKPIKTGHRFRPAYEFDYVA-LDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
              EW+ NG  I+   R    +  D V  L +  V  EDS     +A N  GE  +S A  
Sbjct: 2062 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE-TSSHAFL 2120

Query: 1402 VIAKKDLILESQ 1413
            ++  K LI  +Q
Sbjct: 2121 LVQAKQLITFTQ 2132



 Score =  149 bits (360), Expect = 3e-34
 Identities = 166/695 (23%), Positives = 295/695 (42%), Gaps = 69/695 (9%)

Query: 1939 KESIIRDSQH---ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPV 1995
            +E +I++ ++   ++ LE++  LE+D   K AV        +  F   IKN  + EG  V
Sbjct: 1205 EERLIKEIEYRIIKTTLEEL--LEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGV 1262

Query: 1996 HLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCKA 2054
                 ++    P  ++ WY +G+ ++ G R++  +   G  +L I     ED G Y   A
Sbjct: 1263 TFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA 1320

Query: 2055 TNAVGEAVTTSSVKVDAKSGL----YLDTLDEQRLKKIQELEKYERPK-PIEEEQPGQRP 2109
            +N  G A+ +  + V+  + L    Y+ TL  + + +I+ L      + PI        P
Sbjct: 1321 SNIKGNAICSGKLYVEPAAPLGAPTYIPTL--EPVSRIRSLSPRSVSRSPIRMSPARMSP 1378

Query: 2110 VFLT-ALTSLENLKEGDRAHF--ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
              ++ A  S   +  G R     E ++E +  P   +       K   G   R   D   
Sbjct: 1379 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV--SFKCLEGANCR--FDLKV 1434

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLE 2224
            V   +  T+    G  +      + +  +   +K  G +++I+    P+  G   +    
Sbjct: 1435 VGRPMPETFWFHDGQQI------VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQN 1488

Query: 2225 AQGHST-----RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
              G S+      +E  E ++ P  FV +L+   ++ EG  +  E +V    +PN  I + 
Sbjct: 1489 RAGRSSISVILTVEAVEHQVKP-MFVEKLKNV-NIKEG--SRLEMKVRATGNPNPDIVWL 1544

Query: 2280 HNGKAL--QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             N   +      +  I    G  +L I   V +D+  Y+  AIN  G  T+   + V  +
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604

Query: 2338 GSIISESQR---PEGLEKIRELESAE-----------PFKRPEIPEPVTRQRPVFTQPLQ 2383
             +     ++   P G  + +E+ + E            ++  ++ +   +Q+P F + L 
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLT 1664

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++  ++    AHF+CRL P+ DPT+ VEW  + K +E ++R+   ++FGY S+       
Sbjct: 1665 SL-RLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYS 1723

Query: 2444 EDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE--- 2500
             D G+  CRA+N  G               +  E+Q PEG K +Q++E+  ER + E   
Sbjct: 1724 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEE-LERMAHEGAL 1782

Query: 2501 -----PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555
                   +E +KP    +   P  + EG+ A +  RV   G P  +  WY+NG  ++   
Sbjct: 1783 TGVTTDQKEKQKPDIV-LYPEPVRVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSK 1839

Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            RFR  +D G   LDI    + D G     A N  G
Sbjct: 1840 RFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEG 1873



 Score =  147 bits (356), Expect = 1e-33
 Identities = 112/386 (29%), Positives = 180/386 (46%), Gaps = 22/386 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGH-RYRTFHDFGI 3339
            P F+ ++++V  + EG     + R     +PD  + W  N   + PH + + R     G 
Sbjct: 1510 PMFVEKLKNVN-IKEGSRLEMKVRATGNPNPD--IVWLKNSDIIVPHKYPKIRIEGTKGE 1566

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDST--KANLKCTSKE-----NLILDSQLPRGMEG 3392
              L I     ++S  Y   A NK GRD+T  K N++    E      LI+     R  E 
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 3393 GLEKLQTLEDSMVRRK---DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
               +L+ L     + +       ++EK + P F   L+++   R G  AHFE RLTP  D
Sbjct: 1627 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGP-AHFECRLTPISD 1685

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P + VEW  +GK L+A +R R   +FG+  L+    Y  DSG   CRA N YG   T+A+
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745

Query: 3510 MKVQGKRNIILESQLPKGMEGTIDKIAALE--GYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
            + V+ +++++ ESQLP+G +G + +I  LE   + G +  +T + +    P+    P  +
Sbjct: 1746 LIVKDEKSLVEESQLPEGRKG-LQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1804

Query: 3568 ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDA 3627
             + E  +A F CR+        +V W+ NG+ +    R +   D G   L+I      D 
Sbjct: 1805 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1861

Query: 3628 GLYTCKATNRHGEATVSCKLQVKGRQ 3653
            G     A N  G      KL+++ R+
Sbjct: 1862 GEVKVTAENPEGVIEHKVKLEIQQRE 1887



 Score =  147 bits (355), Expect = 1e-33
 Identities = 76/204 (37%), Positives = 109/204 (53%), Gaps = 4/204 (1%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP      Q V V SG+  R    ++G     + W K  + +    + K L +   YTLL
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            ++EA+P+D+  Y C A N  G A   A   V +P   +   P  +    PP II PL+D 
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP---EVVSPDQEMPVYPPAIITPLQDT 3308

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            + +EGQ   F C++ G  L  V WY  DK IKPS++F+M++  D Y L I+EA+PEDEG 
Sbjct: 3309 VTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 3367

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPD 4716
            Y  VA N+ G+V+  A L +  P+
Sbjct: 3368 YTFVANNAVGQVSSTANLSLEAPE 3391



 Score =  142 bits (345), Expect = 2e-32
 Identities = 113/391 (28%), Positives = 185/391 (47%), Gaps = 33/391 (8%)

Query: 1836 VEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY- 1893
            VE   +Q  P F+ +L     + EG  +  E ++    +PN  + W  N  ++   H+Y 
Sbjct: 1501 VEAVEHQVKPMFVEKLKN-VNIKEG--SRLEMKVRATGNPNPDIVWLKNSDIIVP-HKYP 1556

Query: 1894 --RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ--------SKESII 1943
              R     G AAL I +   +DS  YT  AIN  G+  +  ++NV+         ++ II
Sbjct: 1557 KIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLII 1616

Query: 1944 RDSQHESA------LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHL 1997
                + +       LE +       +++     D    +KP F K + +  +    P H 
Sbjct: 1617 PRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHF 1676

Query: 1998 EATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNA 2057
            E  LTP++DPTM VEW  +G+P++  +R +   +FGY +LD   AY+ D+G   C+ATN 
Sbjct: 1677 ECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNK 1736

Query: 2058 VGEAVTTSSVKV-DAKSGLYLDTLDEQR--LKKIQELEKYERPKPI----EEEQPGQRPV 2110
             G   T++++ V D KS +    L E R  L++I+ELE+      +     +++  Q+P 
Sbjct: 1737 YGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPD 1796

Query: 2111 FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALD 2170
             +     +  L EG+ A F CRV     P   ++W+ NGQ IR   R+R  +D G   LD
Sbjct: 1797 IVLYPEPVRVL-EGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLD 1852

Query: 2171 ILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            I+   + D+G     A N  G   +   L++
Sbjct: 1853 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883



 Score =  140 bits (338), Expect = 1e-31
 Identities = 118/441 (26%), Positives = 191/441 (43%), Gaps = 29/441 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN--RLTTMHDFGYV 1768
            P+F   +K++ + E   +  E ++   G+P   + WL+N   I      ++      G  
Sbjct: 1510 PMFVEKLKNVNIKEG--SRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEA 1567

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK-ASLQLESQ----------HESA 1817
            AL +     +DS  YT  AIN+ G   T   + V+ + A  + E +           E A
Sbjct: 1568 ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIA 1627

Query: 1818 LQKIQQLE---DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874
              +++ L       +++  +  +    Q P F  +L    +L     AH+ECR+ P  DP
Sbjct: 1628 APELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTS-LRLKRFGPAHFECRLTPISDP 1686

Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934
             M VEW  +GK L++ +R R  N+FG+ +LD    Y  DSG  TC+A N  G   +S  L
Sbjct: 1687 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1746

Query: 1935 NVQSKESIIRDSQHESALEKIQYLEDDSRYKR-----AVQDDSFVVEKPQFGKPIKNAEV 1989
             V+ ++S++ +SQ     + +Q +E+  R         V  D    +KP      +   V
Sbjct: 1747 IVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRV 1806

Query: 1990 TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGT 2049
             EG        +T    P  +V WY NG+ +++  RF+  YD G   LDI+   + DTG 
Sbjct: 1807 LEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDTGE 1863

Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRP 2109
                A N   E V    VK++ +      ++  +  +   E   +E  K   E Q   RP
Sbjct: 1864 VKVTAENP--EGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRP 1921

Query: 2110 VFLTALTSLENLKEGDRAHFE 2130
            V  T    +  LK  +R   E
Sbjct: 1922 VDTTETKEVVKLKRAERITHE 1942



 Score =  136 bits (330), Expect = 1e-30
 Identities = 116/410 (28%), Positives = 185/410 (45%), Gaps = 44/410 (10%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F K ++  +V E ++A FE E   EP   ++W +++  ++ +   +I        L+I  
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPS 3072

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              + D+  +  VA     TAK    L VE +  + R            + V V   Q   
Sbjct: 3073 TRMSDAGKYTVVAGGNVSTAK----LFVEGRDVRIRS---------IKKEVQVIEKQRAV 3119

Query: 4533 LDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            ++ +V     +D +W K+G ++  Q   R+K + E   + + I E    D+G+Y  VA  
Sbjct: 3120 VEFEVN-EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA-- 3176

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
              G  R      V+ P               PP++++ L+   V  G+   F   I G+P
Sbjct: 3177 --GRNRSSVTLYVNAPE--------------PPQVLQELQPVTVQSGKPARFCAMISGRP 3220

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P + WYK ++L+      +      EYTL + EAFPED   Y C A N  G  T +A L
Sbjct: 3221 QPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASL 3280

Query: 4711 -----KVTQPDQADNL--PA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                 +V  PDQ   +  PA +TPL+D V  EGQPA+F+ ++ S     + W  +   I 
Sbjct: 3281 SVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIK 3339

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  F+M    +   L I   Y ED GT+T  A  A GQV ++A L +++
Sbjct: 3340 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEA 3389



 Score =  134 bits (325), Expect = 6e-30
 Identities = 128/502 (25%), Positives = 219/502 (43%), Gaps = 32/502 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++  K     HFEC + P  DPT+ +EW  + KPL +  R +  ++F Y SLD 
Sbjct: 1659 FKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDY 1718

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE-AR 2894
               Y  DSGI TC+ATN  G+  TS +L    +K++  ++Q P+G+ GL+ +E+ E  A 
Sbjct: 1719 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1778

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
                   +    E  KP+ I+      +++EG+      +V     P  K+ WY NG+++
Sbjct: 1779 EGALTGVTTDQKEKQKPD-IVLYPEPVRVLEGETARFRCRVTGYPQP--KVNWYLNGQLI 1835

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN---LIE 3011
             +  RF++  D G   LD+VD    D+G     A N  G       +    +++   ++ 
Sbjct: 1836 RKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLR 1894

Query: 3012 RTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQ-IAHY-- 3068
            R   P+    + +   L+  ++K           RP + TT  K++V +   + I H   
Sbjct: 1895 RAPEPRPEFHVHEPGKLQFEVQK---------VDRPVD-TTETKEVVKLKRAERITHEKV 1944

Query: 3069 --EASLIPTGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMV--VLEILGTKTTDSGTYSC 3123
              E+  + +  +    E +Y   T +E   R +      ++    + L   T +      
Sbjct: 1945 PEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEK 2004

Query: 3124 RATNKWGQAEI-SVKLECVDKSKGQK-PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181
            +A  + G+  I + K + ++ S   + P+    IQ+ + +  G  AHF   VV   DP+ 
Sbjct: 2005 KALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC 2063

Query: 3182 KIEWYHNGQPMRHSTRIKTV-SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
              EWY NG  +  S RI     +     L I      DS   + +A N  GE  + A + 
Sbjct: 2064 --EWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLL 2121

Query: 3241 CYGKGGVYLESLQPDSLAKIRE 3262
               K  +       D +AK ++
Sbjct: 2122 VQAKQLITFTQELQDVVAKEKD 2143



 Score =  133 bits (321), Expect = 2e-29
 Identities = 139/532 (26%), Positives = 224/532 (42%), Gaps = 76/532 (14%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P     ++ + V   + A F A +   G P+ ++ W +    +    +   +HD    
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAMIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3248

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L +    PED+  YTC A N+ G A TS        ASL +E     +           
Sbjct: 3249 TLLLIEAFPEDAAVYTCEAKNDYGVATTS--------ASLSVEVPEVVS----------- 3289

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
                  D E+ V   P  IT L   T  SEGQ A ++CR+      +++V WY   K ++
Sbjct: 3290 -----PDQEMPV-YPPAIITPLQD-TVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIK 3339

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS-Q 1947
                +R +       L+I   Y ED G YT  A N +GQ  S+  L++++ ESI+ +  +
Sbjct: 3340 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIE 3399

Query: 1948 HESALEKIQY------LEDDSRYKRAVQ-----------------DDSFVVEK----PQF 1980
             E  +E  ++       E++  +   +Q                    F  EK    P F
Sbjct: 3400 QEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIF 3459

Query: 1981 GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDIL 2040
             K + NA+++ G    L  T+  +  P  +++W+ NG  +     +K  +D    +L IL
Sbjct: 3460 IKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSLIIL 3517

Query: 2041 YAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPI 2100
            +   ED G Y C A+N  G+ + ++ +K+++K   + DT  E  + K   LEK   P P 
Sbjct: 3518 FTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--SLEKLGGPCP- 3574

Query: 2101 EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT 2160
                    P FL  L  +    +G  A FE  V  + +P  T+ WF   +++     Y  
Sbjct: 3575 --------PHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTI 3623

Query: 2161 THD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
             H+  G     +     EDSG Y+CKA N LGE+     L V      + DT
Sbjct: 3624 IHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 3675



 Score =  130 bits (314), Expect = 1e-28
 Identities = 103/387 (26%), Positives = 168/387 (43%), Gaps = 25/387 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF---RFGY 693
            P F+  LK+V   EG ++  E ++   G+P   I WLKN   I    ++  I      G 
Sbjct: 1510 PMFVEKLKNVNIKEGSRL--EMKVRATGNPNPDIVWLKNSDII-VPHKYPKIRIEGTKGE 1566

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT--------------PRATIERTSQ 739
             +L + S   QDS  YT  A++  G   T+  ++V               PR T      
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 740  HPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSD 799
                L+ +       +++  +  +++  Q+P F + L  L  L+    AHFE +LTP+SD
Sbjct: 1627 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPISD 1685

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PTM VEW  DG+P+ A++R+  I  FGY SL+     + D+G  T RA NK G   ++A+
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745

Query: 860  IRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQI 919
            + V    ++  +  +PE R+ +++                    +  QKP+      + +
Sbjct: 1746 LIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDI-VLYPEPV 1804

Query: 920  SIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDA 979
             + EG  A F  R+   G    +V W  +G+ +  S R    ++ G   L I     +D 
Sbjct: 1805 RVLEGETARFRCRV--TGYPQPKVNWYLNGQLIRKSKRFRVRYD-GIHYLDIVDCKSYDT 1861

Query: 980  GHYTCRAYNAIGQATTSANLTIVTKKD 1006
            G     A N  G       L I  ++D
Sbjct: 1862 GEVKVTAENPEGVIEHKVKLEIQQRED 1888



 Score =  127 bits (306), Expect = 1e-27
 Identities = 85/307 (27%), Positives = 136/307 (44%), Gaps = 16/307 (5%)

Query: 66   PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            PGEP+ P F       +  +GG+  F  ++ GNP P V W +   PL    +Y + YN+Q
Sbjct: 1030 PGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1089

Query: 126  TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR----- 180
            TG+  L+I      D GEYT   RN++GE   S  +  E              Y+     
Sbjct: 1090 TGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1149

Query: 181  -----HVSETVEHKAYG--TQGYTTEQSRQTQKVAYTNGTDHSSTDD--FKVDTFEYRLL 231
                  V ET     Y    + Y  EQ+   +K+A       +  +D  F + +FE RL+
Sbjct: 1150 FVQEPEVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1209

Query: 232  REVSFR-ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLS 290
            +E+ +R    T   + E D +    +D S           + +N ++ EG    F  ++S
Sbjct: 1210 KEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMS 1269

Query: 291  GNPRPRVTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            G P P++ W+K+G+R+ +  ++++        +LR+      D G YT  A N  G  + 
Sbjct: 1270 GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAIC 1329

Query: 350  SGYLAVE 356
            SG L VE
Sbjct: 1330 SGKLYVE 1336



 Score =  124 bits (300), Expect = 6e-27
 Identities = 160/632 (25%), Positives = 258/632 (40%), Gaps = 91/632 (14%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            GR     ++ K+ V + E Q A  E  +    +  +   W+ +G  I    + R  Y   
Sbjct: 3098 GRDVRIRSIKKE-VQVIEKQRAVVEFEV---NEDDVDAHWYKDGIEINFQVQERHKYVVE 3153

Query: 3105 MVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
              +  + I  T+ +D+G Y+  A    G+   SV L     +  + P+    +Q +  ++
Sbjct: 3154 RRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV---NAPEPPQVLQELQPVT-VQ 3205

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G+ A F C ++    P  KI WY   Q +    + K + D     L +      D+  Y
Sbjct: 3206 SGKPARF-CAMIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVY 3263

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282
             C A N YG   T A+++                     E+  +    Q+ P      PP
Sbjct: 3264 TCEAKNDYGVATTSASLSV--------------------EVPEVVSPDQEMP----VYPP 3299

Query: 3283 KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
              IT +QD T   EGQ A F+ R   V   DLKV W+   KK+     +R         L
Sbjct: 3300 AIITPLQD-TVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQL 3355

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLI---LDSQLPRGM--------- 3390
            +I   Y E+ G Y  VA N +G+ S+ ANL   + E+++   ++ ++   M         
Sbjct: 3356 EIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLS 3415

Query: 3391 --EGGLE----KLQTLEDSMVRRKDTSV------EEEKGKAPVFTVPLSNIENLREGENA 3438
              E GL     +L  + +++    ++ V       E++G  P+F   +SN + +  G+ A
Sbjct: 3416 AEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-ISMGDVA 3474

Query: 3439 HFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAY 3498
                 +T    P  K++W++NG  L   + ++   D     L I  T  ED GEY C A 
Sbjct: 3475 TLS--VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMAS 3532

Query: 3499 NNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPP 3558
            N+YG+ + +A +K+  K     E       E  + K  +LE   G             PP
Sbjct: 3533 NDYGKTICSAYLKINSKG----EGHKDTETESAVAK--SLEKLGGPC-----------PP 3575

Query: 3559 EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI-NDFGFVIL 3617
             F      +  ++   A FE  +  V + +  V WF   K L T      I N  G    
Sbjct: 3576 HFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 3633

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             +    + D+GLY CKA N  GE+T + +L V
Sbjct: 3634 IVNDPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score =  123 bits (296), Expect = 2e-26
 Identities = 129/511 (25%), Positives = 212/511 (41%), Gaps = 72/511 (14%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E PQ  + ++   V  G P    A ++    P  ++ WY   + +  G + K  +D    
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAMIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 3248

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L ++ A+ ED   Y C+A N  G A T++S+ V                    E+ +  
Sbjct: 3249 TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------------------EVPEVV 3288

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
             P   ++E P   P  +T L       EG  A F+CRV   +   L + W+   +KI+  
Sbjct: 3289 SP---DQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPS 3341

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII------- 2208
              +R T       L+I   Y ED GTY   A N +G+  +T  L +    +I+       
Sbjct: 3342 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQE 3401

Query: 2209 LDTQHPNGLEKIRQLEAQG-HSTRIEVE----------EPKISPPRFVTELRGTTHVFEG 2257
            ++ +           E +G HS  +++           E  + P +F +E  GT  +F  
Sbjct: 3402 IEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIK 3461

Query: 2258 KTAHFECQVEPVHD--------PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
            + ++ +  +  V          P  +I+++ NG  L  +A +   FD    SL I     
Sbjct: 3462 EVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKL 3521

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPE 2369
            ED GEY+  A N  G    +  + + +KG         EG  K  E ESA      ++  
Sbjct: 3522 EDEGEYTCMASNDYGKTICSAYLKINSKG---------EG-HKDTETESAVAKSLEKLGG 3571

Query: 2370 PVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH 2429
            P     P F + L+ I    +G  A F+  +  VG+P   V WF+  K +  S   T  H
Sbjct: 3572 PCP---PHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIH 3625

Query: 2430 D-FGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +  G  +  ++  + ED G+Y+C+A N+LGE
Sbjct: 3626 NPNGSGTFIVNDPQREDSGLYICKAENMLGE 3656



 Score =  123 bits (296), Expect = 2e-26
 Identities = 130/499 (26%), Positives = 211/499 (42%), Gaps = 75/499 (15%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            K+ W+K  Q ++ G + + +HD     L +I+   ED+ +YTC A N  G    S  L+ 
Sbjct: 3223 KISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
                ++V   Q                        E+    P   T L++    EGQ A 
Sbjct: 3283 E-VPEVVSPDQ------------------------EMPVYPPAIITPLQDTVTSEGQPAR 3317

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656
            F+ R   VS   LKV WY  +K +K    F  T       L+I    PED GTYT  A N
Sbjct: 3318 FQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANN 3374

Query: 1657 ALGE-AVTSGI------AIVHSK------------KSIYLESQHEG---ALPRLNQLEDT 1694
            A+G+ + T+ +      +I+H +             S +L ++ EG   A  +L+++ +T
Sbjct: 3375 AVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINET 3434

Query: 1695 SKYQRHSA------QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748
             +    S         E     P+F   + +  ++    A     +I  G PK +++W  
Sbjct: 3435 LELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVI--GIPKPKIQWFF 3492

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
            NGV +  S     + D    +L + +   ED G YTC A N+ G+ + S+ L + SK   
Sbjct: 3493 NGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEG 3552

Query: 1809 QLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRI 1868
              +++ ESA+ K   LE           ++     P F+ +L  P + ++G  A +E  +
Sbjct: 3553 HKDTETESAVAK--SLE-----------KLGGPCPPHFLKELK-PIRCAQGLPAIFEYTV 3598

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
               P P   V W+   K L +   Y    N  G     +     EDSG Y CKA N LG+
Sbjct: 3599 VGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGE 3656

Query: 1928 AVSSIRLNVQSKESIIRDS 1946
            +  +  L V  +++ + D+
Sbjct: 3657 STCAAELLVLLEDTDMTDT 3675



 Score =  121 bits (292), Expect = 6e-26
 Identities = 133/561 (23%), Positives = 225/561 (40%), Gaps = 79/561 (14%)

Query: 3643 VSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETL---HKREEITIEDEKPNPPRFTV 3699
            +    QV+ R   ++E ++   F S T      E T      R  +T+    P PP+   
Sbjct: 3138 IEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQ 3197

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
            E++  + V  G P  F   +   G P  +I W+   +  +TG +   L+D     L +  
Sbjct: 3198 ELQP-VTVQSGKPARFCAMIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE 3254

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
             +  DA  YTC A N +G ATT+A ++           ++P+ +S ++            
Sbjct: 3255 AFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQ------------ 3292

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              E P+   PP  IT ++     E +  RF+CRV   +   L++ WY   K +     +R
Sbjct: 3293 --EMPVY--PPAIITPLQDTVTSEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFR 3345

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII---LQNQVPRG 3936
                     L+I   Y ED G Y   A N  G+  + A +S +    I+   ++ ++   
Sbjct: 3346 MTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEME 3405

Query: 3937 MK---------RSEALTQMEATIKKYTSEV-YLTEDDLY----DVDKK-QPPRFVTQI-Q 3980
            MK           E L   E  + K    +  L+E  +Y    D +K+   P F+ ++  
Sbjct: 3406 MKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSN 3465

Query: 3981 SQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYP 4040
            +  S+ ++ T      +  +G P  K++WFFNG  L     +  ++D    ++   +   
Sbjct: 3466 ADISMGDVAT----LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKL 3521

Query: 4041 EDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHM-KSIEKIREMEASWQVTPE 4099
            ED GEY C A+N YG     A +K   K     D++    + KS+EK+            
Sbjct: 3522 EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKL------------ 3569

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
                     CPP F+     +   +G  A F   V G P P V W      +     Y +
Sbjct: 3570 ------GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTI 3623

Query: 4160 TY--DGMYHFDIPKTRQYDTG 4178
             +  +G   F +   ++ D+G
Sbjct: 3624 IHNPNGSGTFIVNDPQREDSG 3644



 Score =  121 bits (291), Expect = 7e-26
 Identities = 130/547 (23%), Positives = 229/547 (41%), Gaps = 82/547 (14%)

Query: 1831 QRREDVEVAVN--QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
            + R  V + VN  + P+ + +L  P  +  G+ A +   I   P P  ++ WY   ++L 
Sbjct: 3178 RNRSSVTLYVNAPEPPQVLQELQ-PVTVQSGKPARFCAMISGRPQP--KISWYKEEQLLS 3234

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
            +G + +  +D     L ++  + ED+  YTC+A N+ G A +S  L+V+  E +  D + 
Sbjct: 3235 TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE- 3293

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008
                                      V  P    P+++   +EG P   +     V+   
Sbjct: 3294 ------------------------MPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTD 3326

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            ++V WY   + ++    F+ T       L+I  AY ED GTY   A NAVG+  +T+++ 
Sbjct: 3327 LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLS 3386

Query: 2069 VDAKSGLYLDTLDEQ-------------------------RLKKIQELEKYERPKPI--- 2100
            ++A   +  + ++++                         +L KI E  +     P+   
Sbjct: 3387 LEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPT 3446

Query: 2101 --EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158
              + E+ G  P+F+  +++ + +  GD A     V  I  P   I WF NG  +     Y
Sbjct: 3447 KFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADY 3503

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLE 2218
            +   D    +L IL+T  ED G Y C A+N  G+ + +  LK+        DT+  + + 
Sbjct: 3504 KFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVA 3563

Query: 2219 KIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEF 2278
            K   LE  G             PP F+ EL+      +G  A FE  V  V +P   + +
Sbjct: 3564 K--SLEKLGGP----------CPPHFLKELK-PIRCAQGLPAIFEYTV--VGEPAPTVTW 3608

Query: 2279 YHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
            +   K L ++  + I  +  G  +  +     ED+G Y  KA N LG  T A  + V  +
Sbjct: 3609 FKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLE 3668

Query: 2338 GSIISES 2344
             + ++++
Sbjct: 3669 DTDMTDT 3675



 Score =  121 bits (291), Expect = 7e-26
 Identities = 89/309 (28%), Positives = 139/309 (44%), Gaps = 13/309 (4%)

Query: 278   QEGADAQFQVQLSG-NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +EG   ++  ++   +   +VTW+   ++L NS K+EI        L V++  K D G Y
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 337   TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
                  N  G   +   L V+   E Y  D   +      +R T+  + + E+   P+F  
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVY--DYYCRRTMKKIKRRTDT-MRLLERP--PEFTL 25197

Query: 397   VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES--GNHALMITN 454
                ++    G+  RF   +T  P P VTW+ + ++I+   N K    ES  G + L I +
Sbjct: 25198 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 25257

Query: 455   VTLSDSGVVTCVARNKSGETAFQCRLNVI----EKEQVVAPKFVERFSTLNVREGEPVVL 510
             VT  D    T VARNK GE + + +L V       +  + P F    +    +EG+ V  
Sbjct: 25258 VTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCF 25317

Query: 511   NARAVGTPTPRITWQKDGVPIIPNPELRIHTDG-GASTLDIPRAKASDAAWYQCTAQNVA 569
               R  G P P + W+KDG P+   P + I  +G     L I      D  +Y+ TA N A
Sbjct: 25318 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTA 25377

Query: 570   GSTATRARL 578
             GST+ +A L
Sbjct: 25378 GSTSCQAHL 25386



 Score =  114 bits (274), Expect = 9e-24
 Identities = 158/722 (21%), Positives = 281/722 (38%), Gaps = 63/722 (8%)

Query: 3807  KIKELERGRISDAPKEEPIVST-PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
             K   LE   + +      I +T   + +T+ +S TV E E  RF C  + +  P   + W
Sbjct: 26040 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPT--VTW 26097

Query: 3866  YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              R G++L +  R++        + +I  V A D G Y     N  G+   + T++ +K  
Sbjct: 26098 LRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26157

Query: 3926  DIILQNQVPRGMKRSEALTQMEATIKK----------YTSEVYLTEDDLYDVDKKQ---- 3971
                     P  +K  E   +    +K           +   V  TE      +K Q    
Sbjct: 26158 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPREKVQHLPV 26217

Query: 3972  --PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF- 4028
               PP+    ++++ S    E  K  C +        +V W+ +GK L     F   Y   
Sbjct: 26218 SAPPKITQFLKAEAS---KEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274

Query: 4029  GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD-SQLPKHMKSIEKI 4087
             G   +    +   D GEY+C  +   G  +T           I    S++ +  KS +K 
Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334

Query: 4088  REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
              E   + +  P+    E  +  P +   L D  TV     A+F  + TG P+P  +W  +
Sbjct: 26335 TESTVTRKTEPK--APEPISSKPVIVTGLQDT-TVSSDSVAKFAVKATGEPRPTAIWTKD 26391

Query: 4148  GNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDY 4206
             G  I  G +YKL+ D G +  +I KT   D+G                  L +    D  
Sbjct: 26392 GKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD-- 26449

Query: 4207  RGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQ 4266
                            T+ Q+  T  +KT E     Q++ V+  + E+  K ++  E +  
Sbjct: 26450 ---------------TEAQKVST--QKTSEITP--QKKAVV--QEEISQKALRSEEIKMS 26488

Query: 4267  QSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNL 4326
             ++  ++K        + L +E+V K +    ++ + +I  +++T  + A    + + +  
Sbjct: 26489 EAKSQEKLALKEEASKVLISEEVKKSA---ATSLEKSIVHEEITKTSQASEEVRTHAEIK 26545

Query: 4327  DQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVG-DKEITRKITST 4385
               + +++    Q+ V  K  I   ++       V +   ++ +  V G D+ +T K  S 
Sbjct: 26546 AFSTQMSINEGQRLVL-KANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASH 26604

Query: 4386  ETTEI-EHKAQTQERVVEGPV------KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438
                 I    ++T+E +V+         + S  P F  + +   + E +   F  E  GEP
Sbjct: 26605 RDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEP 26664

Query: 4439  LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
              P I+W++ N PI  S +  I        L IR   V DS  +   A+N  G    +A+L
Sbjct: 26665 SPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 26724

Query: 4499  VV 4500
             +V
Sbjct: 26725 MV 26726



 Score =  112 bits (269), Expect = 3e-23
 Identities = 143/652 (21%), Positives = 258/652 (39%), Gaps = 60/652 (9%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH-DFGYVALDILYTYAEDSGT 2181
            EG    F C++     P +   W+ +G++I+ G RY+      G  +L I     ED G 
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIA--WYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315

Query: 2182 YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN--GLEKIRQLEAQGHS-TRIEVEEPK 2238
            Y   A+N  G A+ +  L V     +   T  P    + +IR L  +  S + I +   +
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPAR 1375

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHF--ECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            +SP R          +  G+      E Q+E ++ P   ++   + K L+ A   +  FD
Sbjct: 1376 MSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPV-SFKCLEGA---NCRFD 1431

Query: 2297 FGYVSLDIQ-----HCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQRPEG 2349
               V   +      H   +   +Y+ K +       S I +  T    G     +Q   G
Sbjct: 1432 LKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG 1491

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
               I  + + E  +         + +P+F + L+N+ NI+EG  +  + ++   G+P   
Sbjct: 1492 RSSISVILTVEAVEH--------QVKPMFVEKLKNV-NIKEG--SRLEMKVRATGNPNPD 1540

Query: 2410 VEWFRNEKLIEDSS--RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            + W +N  +I      +I      G  ++ I     +D   Y   A N  G         
Sbjct: 1541 IVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVN 1600

Query: 2468 XXXXXXIQLETQH----PEGMKKIQKLEQP-----HERRSEEP-------DREFE-KPIF 2510
                   + E +     P G  + +++  P     H R  +E        D+E + KP F
Sbjct: 1601 VEVEFA-EPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFF 1659

Query: 2511 TQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDI 2570
             + LT    L     AH+E R+ P+ DP++  EW  +G  L+  +R R  ++FG+ +LD 
Sbjct: 1660 KKKLTS-LRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDY 1718

Query: 2571 NSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVP 2630
                + D+G+  C+A N+ G               +++++  PE  + +Q  E       
Sbjct: 1719 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1778

Query: 2631 E-----MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL 2685
            E     +  D   +Q P    + +   +++EG+      +V     P  K+ W+ NG  +
Sbjct: 1779 EGALTGVTTDQKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQP--KVNWYLNGQLI 1835

Query: 2686 TTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
                R +  +D G+  L I   ++ D+G     A N  G       ++I+ R
Sbjct: 1836 RKSKRFRVRYD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1886



 Score =  110 bits (265), Expect = 1e-22
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 11/228 (4%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS--PDFQIHTFSTK 4465
            ++ P FT+ +Q   V E   A FE    G P+P + W+R+   I  S  P  QI     +
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            + L I  V   +S  ++  A N  G A  +A L+V+ +         PP+F    Q++ V
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET-------APPNFVQRLQSMTV 115

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  VRL  +VTG     V + ++G ++Q  +  +I +E   Y+LLI EAYP+DSG Y 
Sbjct: 116  RQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
              A NS G A   AE +V     ++ P  +TK   +  +I E  + +I
Sbjct: 176  VNATNSVGRATSTAELLVQ--GEEEVPAKKTKTIVSTAQISESRQTRI 221



 Score =  109 bits (262), Expect = 2e-22
 Identities = 86/289 (29%), Positives = 125/289 (43%), Gaps = 24/289 (8%)

Query: 4545  VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
             V W    ++++   + +I  EDG   L + +    D G Y C  +N  GE    AE  V 
Sbjct: 25103 VTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVK 25162

Query: 4605  ---------LPATKDKPKPQT---KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
                         T  K K +T   +    PPE   PL +K    G+ + F   I   P P
Sbjct: 25163 GVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEP 25222

Query: 4653  TVQWYKGDKLIKP---SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
              V WYK  + IKP    K +        Y L I+    +D+ +Y  VA N  G  +  AK
Sbjct: 25223 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 25282

Query: 4710  LKVT-QPDQADNLPALTP-----LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             L VT  P   D+   L P     L +    EGQ   F+ +++    PT++W ++G  +  
Sbjct: 25283 LTVTLHPPPTDS--TLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSL 25340

Query: 4764  TPDFQMIHEG-NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              P+ ++IHEG +   L I +T  EDTG +   AT  AG     A L V+
Sbjct: 25341 GPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389



 Score =  108 bits (259), Expect = 6e-22
 Identities = 179/750 (23%), Positives = 287/750 (38%), Gaps = 90/750 (12%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYING--VELKMGSRFRTTHDFG 2564
            KP+F + L   + + EG  +  E +V   G+P+    W  N   +      + R     G
Sbjct: 1509 KPMFVEKLKNVN-IKEG--SRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKG 1565

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXX--------IIDQAM-RPES 2615
               L I+S V+ D+  Y   AIN+AG                       II +   R + 
Sbjct: 1566 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKE 1625

Query: 2616 WEQIQLKEAAMNKVPEMF-----VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRT 2670
                +L+   +    E +      D   QQ P F   L S  +L      + E ++ P +
Sbjct: 1626 IAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSL-RLKRFGPAHFECRLTPIS 1684

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DP + +EW  +G  L    RL+   +FG  +L      + DSGI TC+ATN  G   ++A
Sbjct: 1685 DPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1744

Query: 2731 SIKIEDRHWLLGESLHPD---SLDRIGALXXXXXXXXXXXXXXXXXXV----FISHLNNI 2783
            ++ ++D   L+ ES  P+    L RI  L                        + +   +
Sbjct: 1745 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPV 1804

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
               EG+   F C V     P  K+ W+ N + +    R++  +D  +  LDI      D+
Sbjct: 1805 RVLEGETARFRCRVTGYPQP--KVNWYLNGQLIRKSKRFRVRYDGIHY-LDIVDCKSYDT 1861

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
            G     A N +G                    +H   K  LE ++Q E+ R    R P  
Sbjct: 1862 GEVKVTAENPEGV------------------IEH---KVKLE-IQQREDFRSVLRRAPE- 1898

Query: 2904 PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLK-IEWYFNGKVLEQG----S 2958
                 P+PE+ +    + Q    +V       E K    LK  E   + KV E+     S
Sbjct: 1899 -----PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRS 1953

Query: 2959 RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKG 3018
            +FK  ++ G+   + +   E  S         K+ E++    +   +KD L+  T+  + 
Sbjct: 1954 KFKRRTEEGY--YEAITAVELKS--------RKKDESY--EELLRKTKDELLHWTK--EL 1999

Query: 3019 TEGLEKIQNLEDSLRKEPGQQPDDDTGRPP-EFTTVFKDIVD--ISEGQIAHYEASLIPT 3075
            TE  EK    E+     P  +PD     P  E   +F+ I    + +G  AH+   ++  
Sbjct: 2000 TEE-EKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVV-- 2056

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAEI 3134
            G      EW+ NG  IE S RI   +    V  L I      DS +   +A N  G+   
Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L    K   Q   FT  +Q++   +    A FEC      +P +K++WY +G  +  
Sbjct: 2117 HAFLLVQAK---QLITFTQELQDVVAKEKDTMATFEC---ETSEPFVKVKWYKDGMEVHE 2170

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              + +  SD     L I      D+ +Y C
Sbjct: 2171 GDKYRMHSDRKVHFLSILTIDTSDAEDYSC 2200



 Score =  106 bits (254), Expect = 2e-21
 Identities = 128/514 (24%), Positives = 209/514 (40%), Gaps = 78/514 (15%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++ G  A F A +   G    ++ W K+ + +    +     +     L +      D
Sbjct: 3202 VTVQSGKPARFCAMIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 3259

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK 1038
            A  YTC A N  G ATTSA+L++   + +  + + P                        
Sbjct: 3260 AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP------------------------ 3295

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
                P  + PL+ T    EGQ A F+ RV   S   + V WY   K+I  +   +     
Sbjct: 3296 -VYPPAIITPLQDT-VTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI--------------DTS 1144
                L+IA    ED G YT VA NA G+   +A++++E   SI              + S
Sbjct: 3351 DTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFS 3410

Query: 1145 SIHRGLYEKTRHIEE---SKFVE--------PMYQIEEISKSK---PVFVQPLSNPPPVS 1190
            S      E+  H  E   SK  E        P+Y  +  S+ +   P+F++ +SN   +S
Sbjct: 3411 SSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-IS 3469

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
             G    L   +  +G P  +++WF NG  +T  + +K  +D    +L I+     D GEY
Sbjct: 3470 MGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEY 3527

Query: 1251 TVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA 1310
            T  A N  G    SA +++  + +   DT+ E A+             K + E +     
Sbjct: 3528 TCMASNDYGKTICSAYLKINSKGEGHKDTETESAV------------AKSL-EKLGGPCP 3574

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L  I   +G     E  +  VG+    V WF   K + T   +   +  +    
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGT 3632

Query: 1371 DLLS-VYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             +++    EDSG+Y C+A N LGE+  +  L V+
Sbjct: 3633 FIVNDPQREDSGLYICKAENMLGESTCAAELLVL 3666



 Score =  105 bits (252), Expect = 4e-21
 Identities = 68/234 (29%), Positives = 107/234 (45%), Gaps = 14/234 (5%)

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            A ++  R   A+ S    +EE        +  P F L   +     G   R D KV G  
Sbjct: 1379 ARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGANCRFDLKVVGRP 1438

Query: 4542 PIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
              + +W  +G+++  D  +K+ ++EDGT +L+I+ A P DSG++  VA N AG  R    
Sbjct: 1439 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG--RSSIS 1496

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             ++++ A + + KP           +E LK+  + EG  +E   +  G P P + W K  
Sbjct: 1497 VILTVEAVEHQVKPM---------FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNS 1547

Query: 4661 KLIKPSKY--FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +I P KY   ++  T  E  L+I     +D   Y   A N AGR T   K+ V
Sbjct: 1548 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601



 Score =  105 bits (252), Expect = 4e-21
 Identities = 116/503 (23%), Positives = 189/503 (37%), Gaps = 44/503 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            PQ ++  Q   V  GK  RF   ++GRP P+++W+  ++ +   +  K L ++   + L+
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFL-HDGQEYTLL 3251

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLN-----VIEKEQ---VVAPKFVERFSTLNVR 503
            +      D+ V TC A+N  G       L+     V+  +Q   V  P  +         
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            EG+P     R  GT   +++W      I P+   R+        L+I  A   D   Y  
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370

Query: 564  TAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLR---HVER 620
             A N  G  ++ A L           +    +    K                    + +
Sbjct: 3371 VANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3430

Query: 621  ARPYIPPGEEDRVYPP----------PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKI 670
                +    E  VYP           P FI  + +     G        +  +G P  KI
Sbjct: 3431 INETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTV--IGIPKPKI 3488

Query: 671  EWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTP 730
            +W  NG  +  S+ +  +F     SL +L   ++D GEYTC A +  G     A L +  
Sbjct: 3489 QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3548

Query: 731  RATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ-RPQFIRPLQDLGELQEGRNAH 789
            +        H +T       E  S     +S+E+      P F++ L+ +    +G  A 
Sbjct: 3549 KG-----EGHKDT-------ETESAV--AKSLEKLGGPCPPHFLKELKPI-RCAQGLPAI 3593

Query: 790  FEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGYVSLNIMHLRAEDAGSYTVRAV 848
            FE   T V +P   V W+K+ + +  S   T I N  G  +  +   + ED+G Y  +A 
Sbjct: 3594 FE--YTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAE 3651

Query: 849  NKLGEAISTASIRVAARSTVTAD 871
            N LGE+   A + V    T   D
Sbjct: 3652 NMLGESTCAAELLVLLEDTDMTD 3674



 Score =  103 bits (248), Expect = 1e-20
 Identities = 169/774 (21%), Positives = 287/774 (37%), Gaps = 105/774 (13%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            ++ +W  NG +I S ++ Q        +L+I +V   D+  YT VA  A   A L     
Sbjct: 2951 ISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEAR 3010

Query: 1135 -VETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGK 1193
             +E R  I    +     EK R + E +  EP   ++ +   + +    +++   + + K
Sbjct: 3011 HIEFRKHIKDIKV----LEKKRAMFECEVSEPDITVQWMKDDQEL---QITDRIKIQKEK 3063

Query: 1194 NIHL----ECRLEPMGDPTM-------RVEWFHNGRSVTVGSRFKTYYDFGFVALDI--- 1239
             +H       R+   G  T+         + F  GR V + S  K           +   
Sbjct: 3064 YVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFE 3123

Query: 1240 IHATSADTGEYT--VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARR 1297
            ++    D   Y   +     +   H   + R I R   +++T+   A E   +   A R 
Sbjct: 3124 VNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM-FISETRQSDAGEYTFV---AGRN 3179

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
               V   +   + PQ  + L  +    G        +   G    ++ W+   + + TG 
Sbjct: 3180 RSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAMIS--GRPQPKISWYKEEQLLSTGF 3237

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSG 1417
            + +  ++     L L+  +PED+ VYTC+A N  G A TS +L V   + +  + + P  
Sbjct: 3238 KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP-- 3295

Query: 1418 LEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK 1477
                                    + P  +  P       EGQ   F+C+   V+ ++LK
Sbjct: 3296 ------------------------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLK 3328

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            V W+   + +     FR         L+I +   ED G YT  A N VG    +  L+  
Sbjct: 3329 VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLE 3388

Query: 1538 STTDIVRS------------------TQNEAGLEQIQV----------LEDRSKYHRTDM 1569
            +   I+                    +  E GL   ++          L   S  + T  
Sbjct: 3389 APESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKF 3448

Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629
              E     PI    + N +I  G  A     +I +     K++W+ N   L   + +   
Sbjct: 3449 DSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFV 3506

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN 1689
             +    +L I+    ED G YTC A N  G+ + S    ++SK   + +++ E A+ +  
Sbjct: 3507 FDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK-- 3564

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRN 1749
             LE                  P F   +K IR A+   A FE  +  VG+P   V W + 
Sbjct: 3565 SLEKLGG-----------PCPPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKE 3611

Query: 1750 GVPIEASNRLTTMHD-FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
               +  S   T +H+  G     +     EDSG Y C+A N LGE+  ++ L V
Sbjct: 3612 NKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score =  103 bits (247), Expect = 2e-20
 Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 19/258 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN--KILEEDGTYTL 4571
            P+FT   Q+V V  G     +  ++G    +V W ++G+ +        +I   DG   L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      +SG+Y   A N +G+A   AE +V             KA  APP  ++ L+ 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------KAETAPPNFVQRLQS 112

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V +G  +    ++ G P P V++Y+    I+ S  FQ+S+  D Y+L I+EA+PED G
Sbjct: 113  MTVRQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK-- 4749
             Y   A NS GR T  A+L V   ++       T +    + E +  + + +I +     
Sbjct: 173  TYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDAR 232

Query: 4750 --PTIQWLREGALIPETP 4765
               T++ + +GA   + P
Sbjct: 233  SIATVEMVIDGAAGQQLP 250



 Score =  102 bits (245), Expect = 3e-20
 Identities = 124/483 (25%), Positives = 190/483 (39%), Gaps = 78/483 (16%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W+   Q +  G + +  HD     L ++  + ED+  Y C+A N  G A  + +
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279

Query: 2199 LKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            L V     +  D + P                        + PP  +T L+ T    EG+
Sbjct: 3280 LSVEVPEVVSPDQEMP------------------------VYPPAIITPLQDTV-TSEGQ 3314

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT-FDFGYVSLDIQHCVPEDAGEYSV 2317
             A F+C+V      +L++ +Y   K ++ +  F +T F+  Y  L+I    PED G Y+ 
Sbjct: 3315 PARFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTY-QLEIAEAYPEDEGTYTF 3370

Query: 2318 KAINALGHCTSAISMTVTAKGSIISE------------------SQRPEGLE-------K 2352
             A NA+G  +S  ++++ A  SI+ E                  S   EGL        K
Sbjct: 3371 VANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3430

Query: 2353 IRE---LESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            I E   L S  P    +         P+F + + N D I  G  A     +I  G P  K
Sbjct: 3431 INETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTVI--GIPKPK 3487

Query: 2410 VEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXX 2469
            ++WF N  L+  S+      D    S+ I   + EDEG Y C ASN  G+          
Sbjct: 3488 IQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKIN 3547

Query: 2470 XXXXIQLETQHPEGM-KKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528
                   +T+    + K ++KL  P              P F + L  P    +G  A +
Sbjct: 3548 SKGEGHKDTETESAVAKSLEKLGGPC------------PPHFLKELK-PIRCAQGLPAIF 3594

Query: 2529 EARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAIN 2587
            E  V  VG+P+    W+    +L     +   H+  G  T  +N     D+GLY+CKA N
Sbjct: 3595 EYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3652

Query: 2588 RAG 2590
              G
Sbjct: 3653 MLG 3655



 Score =  102 bits (244), Expect = 4e-20
 Identities = 70/234 (29%), Positives = 108/234 (46%), Gaps = 16/234 (6%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV+PP +    +N  + EG     +  +SG P P VTW++   ++ +S   +I       
Sbjct: 893  PVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIA 952

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE----------SPTESYVQDQR---- 367
             L +R     DSG +T  A N  G + TS YLAV+          + TE +  +++    
Sbjct: 953  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1012

Query: 368  SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            S+ +  T    TEE+    E A AP F+     + + EG    F C+V G P P V W  
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPA-APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071

Query: 428  NDRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            +   +   Y +K+  N ++G   L+I+     D+G  T V RNK GET+    L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score =  101 bits (243), Expect = 5e-20
 Identities = 142/664 (21%), Positives = 262/664 (39%), Gaps = 57/664 (8%)

Query: 3163  DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             +G+SA F C      +P   + W   GQ +  S R +  +       +I+  Q  D G Y
Sbjct: 26077 EGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 26134

Query: 3223  VCRAYNKYGEDFTRATINCYGKGGVYLESL-------QPDSLAKIRE-LESLQGAQQQTP 3274
                  N  G+     T+    K  V  +++        P+   K  E ++S +  +   P
Sbjct: 26135 SVVVENSEGKQEAEFTLTIQ-KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEP 26193

Query: 3275  STPSAEPPKF-------------ITQIQDVTKLVEGQSAHFEARLVPVDDPDL----KVE 3317
             S P A  P               ++    +T+ ++ +++   A+L  V +  +    +V 
Sbjct: 26194 SHPKAVSPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVT 26253

Query: 3318  WFYNGKKLP-HGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
             W+ +GKKL  +GH    +   G   L I    E + GEY C  + + G  ++K NL+   
Sbjct: 26254 WYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGG--TSKTNLQFMG 26311

Query: 3377  KENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGE 3436
             +    +  ++ +  E      +T E ++ R+ +    E     PV    L +   +    
Sbjct: 26312 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT-TVSSDS 26370

Query: 3437  NAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCR 3496
              A F  + T   +P     W  +GK++  G +++   D G   LEI  T   DSG Y C 
Sbjct: 26371 VAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCT 26428

Query: 3497  AYNNYGEAVTTASMKVQGKRNIILES-QLPKGMEGTIDKIAALEGYSG-----TVDTLTP 3550
               N+ G   ++  + ++  ++   +     K  E T  K A ++         + +    
Sbjct: 26429 VKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS 26488

Query: 3551  EAESGNPPEFTTTPSDLILSE----NSSAHFECRLI--PVNDSSMRVEWFHNGKPLLTGS 3604
             EA+S          S +++SE    +++   E  ++   +  +S   E       +   S
Sbjct: 26489 EAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS 26548

Query: 3605  RVKTINDFGFVILE--IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662
                +IN+   ++L+  I G       L   + TN     +   +  V G    +   Q  
Sbjct: 26549 TQMSINEGQRLVLKANIAGATDVKWVLNGVELTN-----SEEYRYGVSGSDQTLTIKQAS 26603

Query: 3663  SHFKSGTESIQKLEETLHK-REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEP 3721
                +     I K +E + K + ++T+  E  + P F  + +   ++ EG  V F C +  
Sbjct: 26604 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQ-NINEGQNVLFTCEIS- 26661

Query: 3722  VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
              G+P+  I+WF N  P +  S V         +L+I      D+G+YT +A N  G  + 
Sbjct: 26662 -GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSA 26720

Query: 3782  TAKI 3785
             TA +
Sbjct: 26721 TASL 26724



 Score =  100 bits (239), Expect = 1e-19
 Identities = 76/284 (26%), Positives = 123/284 (43%), Gaps = 8/284 (2%)

Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITS----T 4385
            +EV     Q+ V +     D  ++  +   + +  Q Q + + V ++ I R   S    +
Sbjct: 3108 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3167

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445
            +  E    A      V   V   +PP   +++QP  V   + ARF     G P P I WY
Sbjct: 3168 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAMISGRPQPKISWY 3227

Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR- 4504
            +E   +      +      +  L++ + F ED+AV+   A+N  G A  SA+L VE    
Sbjct: 3228 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3287

Query: 4505 --RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                    + PP+     Q+   + GQ  R   +V+GT  + V W    KK++P    ++
Sbjct: 3288 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRM 3346

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
             + + TY L I EAYP+D G Y  VA N+ G+    A   +  P
Sbjct: 3347 TQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAP 3390



 Score =   99 bits (238), Expect = 2e-19
 Identities = 57/193 (29%), Positives = 97/193 (50%), Gaps = 4/193 (2%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYTL 4680
            P   +PL+  +V EG    F   I G P+P V W++  ++I  S     Q+S +     L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             I      + G Y   A N +G+ T  A+L V       N   +  L+ + V +G   + 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNF--VQRLQSMTVRQGSQVRL 123

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + ++T    P +++ R+GA I  + DFQ+  EG+   LLI   Y ED+GT++  AT + G
Sbjct: 124  QVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183

Query: 4801 QVETSAKLVVKSK 4813
            +  ++A+L+V+ +
Sbjct: 184  RATSTAELLVQGE 196



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 139/561 (24%), Positives = 209/561 (37%), Gaps = 77/561 (13%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   Q LQ +  +Q G+ A F C +I  G P  K+ W++ E+L+    +    HD    +
Sbjct: 3193 PQVLQELQPV-TVQSGKPARF-CAMIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3249

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495
            + +     ED  VY C A N  G                 L  + PE +           
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSAS----------LSVEVPEVVS---------- 3289

Query: 2496 RRSEEPDREFEKPIFTQVLTGPSE---LWEGQHAHYEARVVPVGDPSLRFEWYINGVELK 2552
                 PD+E   P++   +  P +     EGQ A ++ RV       L+  WY    ++K
Sbjct: 3290 -----PDQEM--PVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIK 3339

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMR 2612
                FR T       L+I      D G Y   A N  G               I+ + + 
Sbjct: 3340 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIE 3399

Query: 2613 PE-SWEQIQLKEAAMNKVPEMFVDTGVQ------------QAPIFTTHLKS--------Y 2651
             E   E  +   + ++   E      +Q            ++P++ T   S        +
Sbjct: 3400 QEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIF 3459

Query: 2652 DKLVEGQHVYL----EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             K V    + +       V     P  KI+WF NGV LT  A  K  FD    +L I   
Sbjct: 3460 IKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFT 3519

Query: 2708 RNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXX 2767
            + +D G YTC A+N  G+ + +A +KI  +    GE  H D+ +   A+           
Sbjct: 3520 KLEDEGEYTCMASNDYGKTICSAYLKINSK----GEG-HKDT-ETESAVAKSLEKLGGPC 3573

Query: 2768 XXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD 2827
                    F+  L  I C +G    FE  V     PT  + WF  NK L +   Y   H+
Sbjct: 3574 PPH-----FLKELKPIRCAQGLPAIFEYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHN 3626

Query: 2828 FSYVSLDITHTYE-EDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEA 2886
             +     I +  + EDSG+Y CKA N  G +T +  L    +     DT   + K+  EA
Sbjct: 3627 PNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP-CKAKSTPEA 3685

Query: 2887 VEQAEEARLAKGRRPSVPDTE 2907
             E   +  L KG      D+E
Sbjct: 3686 PEDFPQTPL-KGPAVEALDSE 3705



 Score = 98.3 bits (234), Expect = 6e-19
 Identities = 87/371 (23%), Positives = 151/371 (40%), Gaps = 56/371 (15%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV PP I    +++   EG  A+FQ ++SG    +V+W+   +++  S    +    +  
Sbjct: 3295 PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3353

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLA-----------VESPTESYVQDQRSQY 370
             L +      D G YT +A N  G + ++  L+           +E   E  +++  S +
Sbjct: 3354 QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSF 3413

Query: 371  IT---------DTQQRETEERIEI------------SEK-ALAPQFVKVCQDRDVTEGKM 408
            ++         + Q  +  E +E+            SEK    P F+K   + D++ G +
Sbjct: 3414 LSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDV 3473

Query: 409  TRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
                  V G P P++ WF N   +    ++K  V +  +H+L+I    L D G  TC+A 
Sbjct: 3474 ATLSVTVIGIPKPKIQWFFNGVLLTPSADYK-FVFDGDDHSLIILFTKLEDEGEYTCMAS 3532

Query: 469  NKSGETAFQCRLNV---------IEKEQVVA-----------PKFVERFSTLNVREGEPV 508
            N  G+T     L +          E E  VA           P F++    +   +G P 
Sbjct: 3533 NDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPA 3592

Query: 509  VLNARAVGTPTPRITWQKDGVPIIPNPELR-IHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +     VG P P +TW K+   +  +     IH   G+ T  +   +  D+  Y C A+N
Sbjct: 3593 IFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3652

Query: 568  VAGSTATRARL 578
            + G +   A L
Sbjct: 3653 MLGESTCAAEL 3663



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 123/499 (24%), Positives = 197/499 (39%), Gaps = 75/499 (15%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI W+K    L+TG + K   D    TL +     +D+ +YTC+A N  G A ++AS
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            + +E     + E + PD    +                       I+ L + V  EG   
Sbjct: 3280 LSVE-----VPEVVSPDQEMPV------------------YPPAIITPLQDTVTSEGQPA 3316

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851
             F+C V  +    LK+ W+  +K +     ++ T       L+I   Y ED G YT  A 
Sbjct: 3317 RFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVAN 3373

Query: 2852 NSKGSATTSGSLRCTGDKNIYFDTQHPQ--------GKAGLEAVEQ---AEEARLAK--- 2897
            N+ G  +++ +L     ++I  +    +          + L A E+   + E +L+K   
Sbjct: 3374 NAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINE 3433

Query: 2898 -----GRRPSVPDTEYPKPEWIIPI----AAEHQLVEGQVLHLEGQVEPKNDPDLKIEWY 2948
                    P  P     + E   PI     +   +  G V  L   V     P  KI+W+
Sbjct: 3434 TLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLS--VTVIGIPKPKIQWF 3491

Query: 2949 FNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            FNG +L   + +K   D    +L ++     D G YTC A N  G+   S+ +   SK  
Sbjct: 3492 FNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG- 3550

Query: 3009 LIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHY 3068
                    +G +  E    +  SL K  G         PP F    K I   ++G  A +
Sbjct: 3551 --------EGHKDTETESAVAKSLEKLGGP-------CPPHFLKELKPI-RCAQGLPAIF 3594

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATN 3127
            E +++  G+ +  + WF   K +  S     ++   G     +   +  DSG Y C+A N
Sbjct: 3595 EYTVV--GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 3652

Query: 3128 KWGQ----AEISVKLECVD 3142
              G+    AE+ V LE  D
Sbjct: 3653 MLGESTCAAELLVLLEDTD 3671



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 93/361 (25%), Positives = 145/361 (40%), Gaps = 49/361 (13%)

Query: 2508  PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
             P+  Q++    E  EG H  Y  ++    D S +  WY    +L+   ++  T++ G   
Sbjct: 25072 PVSGQIMHAVGE--EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAI 25128

Query: 2568  LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
             L +  +   D G Y CK +N  G               + D   R  + ++I+ +   M 
Sbjct: 25129 LYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCR-RTMKKIKRRTDTMR 25187

Query: 2628  KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                       +++ P FT  L +    V G++V     +    +P+  + W+K+G  +  
Sbjct: 25188 L---------LERPPEFTLPLYNKTAYV-GENVRFGVTITVHPEPH--VTWYKSGQKIKP 25235

Query: 2688  GAR-LKSTF--DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
             G    K TF  D GL  L+INS+  DD   YT  A N  GE    A + +         +
Sbjct: 25236 GDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV---------T 25286

Query: 2745  LHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPT 2804
             LHP   D                       +F   L N  C+EG ++ FE  V     PT
Sbjct: 25287 LHPPPTD------------------STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPT 25328

Query: 2805  LKIEWFFNNKPLPSGTRYKSTHD-FSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             LK  W  + +PL  G   +  H+   Y +L I  T  ED+G Y   ATN+ GS +    L
Sbjct: 25329 LK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHL 25386

Query: 2864  R 2864
             +
Sbjct: 25387 Q 25387



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 93/345 (26%), Positives = 136/345 (39%), Gaps = 41/345 (11%)

Query: 1858  EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
             EG    Y C+IE Y D + +V WYF  + L++  +Y  + + G A L +  +   D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 1918  TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK 1977
              CK +N+ G+  S   L V+    +  D      ++KI+   D  R          +   
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVY-DYYCRRTMKKIKRRTDTMR---------LLERP 25192

Query: 1978  PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
             P+F  P+ N     G  V    T+T   +P   V WY +G+ ++ G              
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDN------------ 25238

Query: 2038  DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             D  Y +  D G Y     +   +     +V    K G       E   K   +L     P
Sbjct: 25239 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG-------EDSCK--AKLTVTLHP 25289

Query: 2098  KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
              P +      RP+F   L + E  +EG    FE RV  I  P  T+ W  +GQ +  G  
Sbjct: 25290 PPTDST---LRPMFKRLLANAE-CQEGQSVCFEIRVSGIPPP--TLKWEKDGQPLSLGPN 25343

Query: 2158  YRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 H+   Y AL I  T  ED+G Y   ATN  G       L+V
Sbjct: 25344 IEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388



 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 59/189 (31%), Positives = 88/189 (46%), Gaps = 3/189 (1%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F +  Q   V EG    F+  ++G P PEV+WF + + I       + ++ S   A 
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I  VT ++SG  +  A N SG+      L V  K +   P FV+R  ++ VR+G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV--KAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L  R  G P P + + +DG  I  + + +I  +G   +L I  A   D+  Y   A N  
Sbjct: 123 LQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182

Query: 570 GSTATRARL 578
           G   + A L
Sbjct: 183 GRATSTAEL 191



 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 96/405 (23%), Positives = 174/405 (42%), Gaps = 52/405 (12%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F + +   +V E E ARFE E   E    +KW+++   IK    + I +     IL+I +
Sbjct: 5879 FLRPLTDLQVREKEMARFECELSRENAK-VKWFKDGAEIKKGKKYDIISKGAVRILVINK 5937

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              ++D A ++        TA+ S  L V E+            FT    N+ V+    ++
Sbjct: 5938 CLLDDEAEYSCEVR----TARTSGMLTVLEEEAV---------FTKNLANIEVSETDTIK 5984

Query: 4533 LDTKVTGTKP-IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            L  +V+  KP  +V W K  +++    R +IL E     L+I  A+ +D+G Y C     
Sbjct: 5985 LVCEVS--KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC----- 6037

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
                         LP+++   K   K      E I   ++  + EG+  EF C I  +  
Sbjct: 6038 ------------RLPSSRTDGK--VKVHELAAEFISKPQNLEILEGEKAEFVCSISKESF 6083

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV--AYNSAGRVTVAAK 4709
            P VQW + DK ++    + +     +  L + +A  +D G Y  +  A  +A  +TV  K
Sbjct: 6084 P-VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEK 6142

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            L++           + PL+D  V E Q   F  ++ ++     +W R    I ++  + +
Sbjct: 6143 LRI-----------VVPLKDTRVKEQQEVVFNCEVNTE-GAKAKWFRNEEAIFDSSKYII 6190

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVVKSK 4813
            + +     L I + + +D   +    T   G+ V+++A L+V+ +
Sbjct: 6191 LQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEE 6235



 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 109/509 (21%), Positives = 193/509 (37%), Gaps = 33/509 (6%)

Query: 4309  VTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQT 4368
             VT        +QR ++ + ++  V  +  + +    P     SE         V  Q   
Sbjct: 25966 VTGGDYTTYASQRRDEEVPRS--VFPELTRTEAYAVPSFKKTSEMEASSSVREVKSQMTE 26023

Query: 4369  QKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQA 4428
              +E +   E +      ++  +E K+  +E+     +K +       K +   V+E E A
Sbjct: 26024 TRESLSSYEHSAS-AEMKSAALEEKS-LEEKSTTRKIKTTLAARILTKPRSMTVYEGESA 26081

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             RF  + DGEP+P + W R+   +  S   Q+ T   KS   I  V   D   ++ V EN 
Sbjct: 26082 RFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 26141

Query: 4489  GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
              G  +    L +++ R   +    PP   + +    V S + V+   +V   +P     +
Sbjct: 26142 EGKQEAEFTLTIQKARVTEKAVTSPP--RVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAV 26199

Query: 4549  KNGKKVQPDIRNKI----LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
              +  + +P  R K+    +      T  +     ++  K  CV  +S   A+   E    
Sbjct: 26200 -SPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK---EVTWY 26255

Query: 4605  LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
                 K K     +   +     E LK   + E    E+ C+I G+         G     
Sbjct: 26256 KDGKKLKENGHFQFHYSADGTYE-LKINNLTESDQGEYVCEISGE--------GGTSKTN 26306

Query: 4665  PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
                  Q  ++  E   +ISE    D+              TV  K +   P+   + P +
Sbjct: 26307 LQFMGQAFKSIHEKVSKISETKKSDQ---------KTTESTVTRKTEPKAPEPISSKPVI 26357

Query: 4725  -TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNT 4783
              T L+D  V     A+F  + T + +PT  W ++G  I +   +++  +     L I  T
Sbjct: 26358 VTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKT 26417

Query: 4784  YEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
                D+G +TC    +AG V +S KL +K+
Sbjct: 26418 DTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26446



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 105/422 (24%), Positives = 177/422 (41%), Gaps = 54/422 (12%)

Query: 4389 EIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN 4448
            E E+   T + +VEG V       F K++Q   V E      E     E +   KWY  +
Sbjct: 2204 EDENVKTTAKLIVEGAVVE-----FVKELQDIEVPESYSGELECIVSPENIEG-KWYHND 2257

Query: 4449 FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              +K++  + I +   +  L ++ V  ED   ++ V + +  T K      ++ K R   
Sbjct: 2258 VELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCK------LKMKPR--- 2308

Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568
                P +      +  V  G +V+L+ KV+  + ++  W+K+G++VQP  R  I+ +  +
Sbjct: 2309 ----PIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQS 2363

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            + LLI +   +D+G Y    I + G +      V S+                  ++I P
Sbjct: 2364 HMLLIEDMTKEDAGNYS-FTIPALGLSTSGRVSVYSV------------------DVITP 2404

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            LKD  V EG      CK+    + +V+WY  D+ IKP    Q      +  L I+     
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            DEG YK +     GRV     L V      + +  +  LRD+   E Q   F+ ++ S  
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSV------EKIKIIRGLRDLTCTETQNVVFEVEL-SHS 2513

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
               + W  +   I  +  +++   G    L + N  ++D G +    T  AG+  TS KL
Sbjct: 2514 GIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKY----TFYAGENMTSGKL 2569

Query: 4809 VV 4810
             V
Sbjct: 2570 TV 2571



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 105/404 (25%), Positives = 168/404 (41%), Gaps = 44/404 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P + T  ++     E +   FEV  + E +   KW +    IK++   Q+ T      L 
Sbjct: 2922 PIMITSMLKDINAEEKDTITFEVTVNYEGISY-KWLKNGVEIKSTDKCQMRTKKLTHSLN 2980

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            IR V   D+A +  VA    G A  +A L VE +  + R  I         +++ V   +
Sbjct: 2981 IRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHI---------KDIKVLEKK 3027

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
                + +V+    I V W+K+ +++Q   R KI +E   + LLI      D+GKY  VA 
Sbjct: 3028 RAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAG 3086

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
             +   A+   E        +D    + ++     ++IE  K + V     +EF    V +
Sbjct: 3087 GNVSTAKLFVE-------GRD---VRIRSIKKEVQVIE--KQRAV-----VEFE---VNE 3126

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                  WYK    I      +     +   + + ISE    D G+Y  V    AGR   +
Sbjct: 3127 DDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV----AGRNRSS 3182

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              L V  P+    L  L P   + V  G+PA+F   I+ + +P I W +E  L+      
Sbjct: 3183 VTLYVNAPEPPQVLQELQP---VTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKC 3239

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + +H+G    LL+   + ED   +TC A    G   TSA L V+
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 68/206 (33%), Positives = 91/206 (44%), Gaps = 15/206 (7%)

Query: 4513  PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK--ILEED-GTY 4569
             PP FTL   N     G+ VR    +T      V W K+G+K++P   +K    E D G Y
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 25251

Query: 4570  TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL--PATKDKPKPQTKAANAPPEIIE 4627
              L I      D  +Y  VA N  GE  C A+  V+L  P T    +P  K   A  E   
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAE--- 25308

Query: 4628  PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAF 4686
                     EGQ++ F  ++ G P PT++W K G  L        +    D Y L I +  
Sbjct: 25309 ------CQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTL 25362

Query: 4687  PEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             PED G Y+  A N+AG  +  A L+V
Sbjct: 25363 PEDTGYYRVTATNTAGSTSCQAHLQV 25388



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 58/218 (26%), Positives = 98/218 (44%), Gaps = 8/218 (3%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P   ++  N+ +  G  A   V + G P+P++ WF NG  L  S  ++ +   +  +L +
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
              T+  D G YT +A N  G  + S YL + S  E +         T+T+     + +E 
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKD-------TETES-AVAKSLEK 3568

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
                  P F+K  +     +G    F+  V G P P VTWF  ++Q+     + I+ N +
Sbjct: 3569 LGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 3628

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            G+   ++ +    DSG+  C A N  GE+     L V+
Sbjct: 3629 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVL 3666



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 146/718 (20%), Positives = 272/718 (37%), Gaps = 57/718 (7%)

Query: 1132  SMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
             S   ETR S+ +         K+  +EE K +E      +I  +    +        V E
Sbjct: 26019 SQMTETRESLSSYEHSASAEMKSAALEE-KSLEEKSTTRKIKTTLAARILTKPRSMTVYE 26077

Query: 1192  GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
             G++    C  +  G+P   V W   G+ ++  +R +          +I    ++D G Y+
Sbjct: 26078 GESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYS 26135

Query: 1252  VRAVNHLGSAH---TSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVR------ 1302
             V   N  G      T  I +       VT     ++ E      +A +  K+V+      
Sbjct: 26136 VVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSH 26195

Query: 1303  -----------------EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVE 1345
                              + + V   P+ ++ L    + E     L C ++    +   V 
Sbjct: 26196 PKAVSPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAK--LTCVVESSVLRAKEVT 26253

Query: 1346  WFCNGKPIKTGHRFRPAYEFDYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
             W+ +GK +K    F+  Y  D    L + ++   D G Y C+ + + G + T+      A
Sbjct: 26254 WYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQA 26313

Query: 1405  KKDLILESQHPSGLEKIQY--LEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHV 1462
              K +  +    S  +K      E T   K      E ++ KP  VT    +++       
Sbjct: 26314 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVT---GLQDTTVSSDS 26370

Query: 1463  HFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAV 1522
               +  ++   +      W K+G+ +T G +++   D G   L+I      DSG+YTC   
Sbjct: 26371 VAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK 26430

Query: 1523  NLVGTDEVSCRLTCRSTTDIVR---STQNEAGL---EQIQVLEDRS-KYHRTDMV--DEV 1573
             N  G+   SC+LT ++  D      STQ  + +   ++  V E+ S K  R++ +   E 
Sbjct: 26431 NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEA 26490

Query: 1574  TTQAPI-----CTTSLKNVEIKEGQRAHFERRLI--PVSDATLKVEWYHNNKPLKSGSRF 1626
              +Q  +      +  L + E+K+      E+ ++   ++  +   E    +  +K+ S  
Sbjct: 26491 KSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQ 26550

Query: 1627  TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLES-QHEGAL 1685
                N    + L        D             E    G++      +I   S + EG L
Sbjct: 26551 MSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGIL 26610

Query: 1686  PRLNQL-EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRV 1744
               +++  E   K Q      + ++ AP F    +   + E Q   F   +   G+P   +
Sbjct: 26611 TCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEI--SGEPSPEI 26668

Query: 1745  EWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             EW +N +PI  S+ ++        +L ++  +  DSG YT +A N  G+   +++L V
Sbjct: 26669 EWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 91.9 bits (218), Expect = 5e-17
 Identities = 107/400 (26%), Positives = 161/400 (40%), Gaps = 48/400 (12%)

Query: 3546 DTLTPEAESG-NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            + ++P+ E    PP   T   D + SE   A F+CR   V+ + ++V W+   K +   S
Sbjct: 3286 EVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP-S 3341

Query: 3605 RVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGII---LEPQ 3660
            R   +  F     LEI   Y  D G YT  A N  G+ + +  L ++  + I+   +E +
Sbjct: 3342 RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQE 3401

Query: 3661 LPSHFKSGTESIQKLEET-LHKRE------EITIE--DEKP-NPPRFTVE--------IK 3702
            +    K  + S    EE  LH  E        T+E   E P  P +F  E        IK
Sbjct: 3402 IEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIK 3461

Query: 3703 D--NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYI 3760
            +  N D+  G        V  +G P  +I WF NG      +    + D    +L I + 
Sbjct: 3462 EVSNADISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFT 3519

Query: 3761 YARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAP 3820
               D GEYTC A+N +G      K  CSA   I           GE  K+ E        
Sbjct: 3520 KLEDEGEYTCMASNDYG------KTICSAYLKI--------NSKGEGHKDTETESAVAKS 3565

Query: 3821 KEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
             E+     PP F+ ++K     +     FE  V  +  P   + W++  K L +   Y  
Sbjct: 3566 LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPT--VTWFKENKQLCTSVYYTI 3623

Query: 3881 VYDM-GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            +++  G  +  +     EDSG YIC+A N  GE    A +
Sbjct: 3624 IHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 3663



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 100/399 (25%), Positives = 173/399 (43%), Gaps = 43/399 (10%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            ++  RV E ++  F  E + E     KW+R    I +S  + I        L IR   ++
Sbjct: 6149 LKDTRVKEQQEVVFNCEVNTEGAKA-KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 6207

Query: 4477 DSAVF-AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            D A +  ++  +RG   K +ANL+VEE+  +    IV P      +++     + V    
Sbjct: 6208 DQANYNVSLTNHRGENVKSAANLIVEEEDLR----IVEP-----LKDIETMEKKSVTFWC 6258

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            KV     + + W KNG++V  D R     +   + L I +    D G+Y    I +AG+ 
Sbjct: 6259 KVNRLN-VTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEY----IVTAGQD 6313

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
            +  AE ++                 AP E +E L+D+ V E     FSC++  +    V+
Sbjct: 6314 KSVAELLI---------------IEAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVK 6357

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            WY+  + IK  K ++  +    + L I +   +DE +Y C   +   R    A+L V + 
Sbjct: 6358 WYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSR----ARLFVEEI 6413

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                 +  + P +DI+   G    F  ++ +K K  +QWLR   ++ +    QM+ EG  
Sbjct: 6414 P----VEIIRPPQDILEAPGADVVFLAEL-NKDKVEVQWLRNNMVVVQGDKHQMMSEGKI 6468

Query: 4776 AVLLIGNTYEEDTG--TFTCRATTAAGQVETSAKLVVKS 4812
              L I +    D G   F  +   A  ++E +A   +K+
Sbjct: 6469 HRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKT 6507



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 61/214 (28%), Positives = 96/214 (44%), Gaps = 12/214 (5%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P F     N +++ G +  L   V G     + W  NG  + P    K + +   ++L+I
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA----------PP 4623
            L    +D G+Y C+A N  G+  C A   ++      K   +T++A A          PP
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK-DTETESAVAKSLEKLGGPCPP 3575

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRI 4682
              ++ LK    A+G    F   +VG+P PTV W+K +K +  S Y+ +    +   T  +
Sbjct: 3576 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 3635

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            ++   ED G Y C A N  G  T AA+L V   D
Sbjct: 3636 NDPQREDSGLYICKAENMLGESTCAAELLVLLED 3669



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 99/434 (22%), Positives = 182/434 (41%), Gaps = 40/434 (9%)

Query: 1005  KDIIAESQHPGGLE-KIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF 1063
             ++ ++  +H    E K   LE+ S   K T  ++K T   R L   +    + EG+SA F
Sbjct: 26025 RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMT-VYEGESARF 26083

Query: 1064  EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNA 1123
                 +   +   TV W   G+ ++++ R Q          +I+SV+A D G Y+VV  N+
Sbjct: 26084 SC--DTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 26141

Query: 1124  AGEAQLSASMTVE----TRSSIDTSSIHRGLYEKTRHIE------ESKFVEPMY-QIEEI 1172
              G+ +   ++T++    T  ++ +    +    + +  E        K  EP + +    
Sbjct: 26142 EGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSP 26201

Query: 1173  SKSKPV---FVQ--PLSNPPPVSE------GKNI-HLECRLEPMGDPTMRVEWFHNGRSV 1220
             +++KP     VQ  P+S PP +++       K I  L C +E        V W+ +G+ +
Sbjct: 26202 TETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL 26261

Query: 1221  TVGSRFKTYYDF-GFVALDIIHATSADTGEYTVRAVNHLGSAHTS------AIVRVIERS 1273
                  F+ +Y   G   L I + T +D GEY        G++ T+      A   + E+ 
Sbjct: 26262 KENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKV 26321

Query: 1274  DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
               +++T+        +  E    R  + +    +   P     L +  TV   +V  +  
Sbjct: 26322 SKISETKKSDQ----KTTESTVTRKTEPKAPEPISSKPVIVTGLQD-TTVSSDSV-AKFA 26375

Query: 1334  LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
             ++  G+      W  +GK I  G +++ + +     L++      DSG+YTC   N  G 
Sbjct: 26376 VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGS 26435

Query: 1394  AVTSCALRVIAKKD 1407
               +SC L + A KD
Sbjct: 26436 VSSSCKLTIKAIKD 26449



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 65/267 (24%), Positives = 107/267 (40%), Gaps = 7/267 (2%)

Query: 79    KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
             ++ R   G N +F   ++  PT  V W      L E +K  + Y   +G ++L I     
Sbjct: 25884 RSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSK--IHYTNTSGVLTLEILDCHT 25941

Query: 139   GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
              D G Y     N  GEA  S Y   +                 V  +V  +   T+ Y  
Sbjct: 25942 DDSGTYRAVCTNYKGEA--SDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAV 25999

Query: 199   EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDR 258
                ++T ++  ++      +     +T E     E S    +    + E  ++      R
Sbjct: 26000 PSFKKTSEMEASSSVREVKSQ--MTETRESLSSYEHSASAEMKSAALEEKSLE-EKSTTR 26056

Query: 259   SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
              +      +I  KPR+  + EG  A+F     G P P VTW + GQ L  S +H++ TT 
Sbjct: 26057 KIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK 26116

Query: 319   NHTTLRVRNTQKSDSGHYTLLAENPNG 345
               +T  + + Q SD G+Y+++ EN  G
Sbjct: 26117 YKSTFEISSVQASDEGNYSVVVENSEG 26143



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 166/770 (21%), Positives = 293/770 (38%), Gaps = 76/770 (9%)

Query: 4058  ETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLP 4117
             E K+ +  T +    Y+      MKS   + E     + T  ++     AR     ++ P
Sbjct: 26016 EVKSQMTETRESLSSYEHSASAEMKSAA-LEEKSLEEKSTTRKIKTTLAAR----ILTKP 26070

Query: 4118  DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYD 4176
              ++TV EGE ARF C   G P P V WL  G  +   +R+++T       F+I   +  D
Sbjct: 26071 RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASD 26130

Query: 4177  TGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFE 4236
              G   V+             L +       + V  + PR    E         +  K  +
Sbjct: 26131 EGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV-TSPPRVKSPEPRVKSPEAVKSPKRVK 26189

Query: 4237  ERQVLQRQGV--IDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESR 4294
               +    + V   + +P  + KV   P +     + +    E   ++ +L    V++ S 
Sbjct: 26190 SPEPSHPKAVSPTETKPTPREKVQHLPVSA-PPKITQFLKAEASKEIAKL--TCVVESSV 26246

Query: 4295  LRESTHQYAIPGDKVTSN---TVAKSMAQRYE---DNL---DQTEEVTEQRVQKKVTQKP 4345
             LR     +   G K+  N       S    YE   +NL   DQ E V E   +   T K 
Sbjct: 26247 LRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGG-TSKT 26305

Query: 4346  RIPDPSES--TVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEG 4403
              +    ++  ++H K   V+K  +T+K    D++ T    ST T + E KA         
Sbjct: 26306 NLQFMGQAFKSIHEK---VSKISETKK---SDQKTTE---STVTRKTEPKA--------- 26347

Query: 4404  PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
             P   S  P+    +Q   V     A+F V+  GEP P   W ++   I     +++    
Sbjct: 26348 PEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDK 26407

Query: 4464  TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE-KRRQGRGGIVPPSFTLTAQN 4522
                 L I +    DS ++    +N  G+   S  L ++  K  + +      +  +T Q 
Sbjct: 26408 GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQK 26467

Query: 4523  VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
               V   +   +  K   ++ I +   K+ +K+        L+E+ +  L+        S 
Sbjct: 26468 KAVVQEE---ISQKALRSEEIKMSEAKSQEKL-------ALKEEASKVLI--------SE 26509

Query: 4583  KYECVAINSAGEARCDAECVVSLPATKD-KPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
             + +  A  S  ++    E   +  A+++ +   + KA +    I E         GQ + 
Sbjct: 26510 EVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINE---------GQRLV 26560

Query: 4642  FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
                 I G     V+W      +  S+ ++   +  + TL I +A   DEG   C++    
Sbjct: 26561 LKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26618

Query: 4702  GRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
             G   V  +  +T   +  + PA ++  R   + EGQ   F  +I+ +  P I+W +    
Sbjct: 26619 G--IVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLP 26676

Query: 4761  IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             I  + +  +    N   L I N    D+G +T +A    GQ   +A L+V
Sbjct: 26677 ISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 79/297 (26%), Positives = 132/297 (44%), Gaps = 23/297 (7%)

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITV-MQAPQFSRALHNIETVEGTNVHLECR 1333
            I   T  E+  E +   E     T +V   + + +  P     L N+  +EG +V LEC 
Sbjct: 860  ITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECH 919

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            +   G  +  V W+     I++   F+  ++     L +   + EDSG +TC A N+ G 
Sbjct: 920  IS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGT 977

Query: 1394 AVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII--DESVT---------I 1442
              TSC L V   ++   E +  +  EK    E+    +  D++  D S+T          
Sbjct: 978  VSTSCYLAVQVSEE--FEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLTEEQAGPGEPA 1034

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD--FG 1500
             P F+T+P  ++ ++EG  V F C++    +    V W K+G P+T G+R++  ++   G
Sbjct: 1035 APYFITKP-VVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1091

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
               L I    A+D+G YT    N  G    S  L   +  +++  +Q E  L Q QV
Sbjct: 1092 ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEM-LYQTQV 1147



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 104/457 (22%), Positives = 176/457 (38%), Gaps = 38/457 (8%)

Query: 1774  YVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRR 1833
             Y  P    T    A + + E  +  T   +++ SL       SA  K   LE+ S  ++ 
Sbjct: 25997 YAVPSFKKTSEMEASSSVREVKSQMT---ETRESLSSYEHSASAEMKSAALEEKSLEEKS 26053

Query: 1834  EDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
                ++    A R +T+    T + EG+SA + C  +  P P   V W   G+VL +  R+
Sbjct: 26054 TTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPT--VTWLRKGQVLSTSARH 26110

Query: 1894  RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE-------SIIRDS 1946
             + +     +  +I +V   D G Y+    N+ G+  +   L +Q          S  R  
Sbjct: 26111 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVK 26170

Query: 1947  QHESALEKIQYLEDDSRYKRAVQDDSFVV----------EKPQF---GKPIKNAEVTEGH 1993
               E  ++  + ++   R K         V          EK Q      P K  +  +  
Sbjct: 26171 SPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPREKVQHLPVSAPPKITQFLKAE 26230

Query: 1994  PVHLEATLTPVNDPTM----RVEWYCNGRPVQQGHRFKTTYDF-GYVALDILYAYAEDTG 2048
                  A LT V + ++     V WY +G+ +++   F+  Y   G   L I      D G
Sbjct: 26231 ASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQG 26290

Query: 2049  TYMCKATNAVGEAVTTSSVKVDAKSGLY--LDTLDEQRL--KKIQELEKYERPKPIEEEQ 2104
              Y+C+ +   G + T       A   ++  +  + E +   +K  E     + +P   E 
Sbjct: 26291 EYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEP 26350

Query: 2105  PGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF 2164
                +PV +T L     +     A F   V+   +P  T  W  +G+ I  G +Y+ + D 
Sbjct: 26351 ISSKPVIVTGLQDT-TVSSDSVAKFA--VKATGEPRPTAIWTKDGKAITQGGKYKLSEDK 26407

Query: 2165  GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             G   L+I  T   DSG Y C   N  G   ++C L +
Sbjct: 26408 GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 151/717 (21%), Positives = 261/717 (36%), Gaps = 77/717 (10%)

Query: 3534  KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEW 3593
             K AALE  S    + T + ++       T P  + + E  SA F C      +    V W
Sbjct: 26040 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTD--GEPVPTVTW 26097

Query: 3594  FHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
                G+ L T +R +          EI  V   D G Y+    N  G+      L ++  +
Sbjct: 26098 LRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26157

Query: 3654  GIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKP---NPPRFTVEIKDNID-VPE 3709
                     P   KS    ++  E     +   + E   P   +P       ++ +  +P 
Sbjct: 26158 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPREKVQHLPV 26217

Query: 3710  GGP---------------VHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLNDFGF 3752
               P                   C VE        + W+ +G+        + H   D G 
Sbjct: 26218 SAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD-GT 26276

Query: 3753  IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE-SQLPQGM-SGEKIKE 3810
               L I+ +   D GEY C  + + G++ T  +    A + I  + S++ +   S +K  E
Sbjct: 26277 YELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTE 26336

Query: 3811  LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK 3870
                 R ++    EPI S+ P  +T ++  TV      +F   V+   +P+    W ++GK
Sbjct: 26337 STVTRKTEPKAPEPI-SSKPVIVTGLQDTTVSSDSVAKFA--VKATGEPRPTAIWTKDGK 26393

Query: 3871  LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG-------------EDFTKA 3917
              +  G +Y+   D G   L+I      DSG Y C   N  G             +D    
Sbjct: 26394 AITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26453

Query: 3918  TISCKKLPDI------ILQNQVPRG------MKRSEALTQMEATIKKYTSEVYLTEDDLY 3965
              +S +K  +I      ++Q ++ +       +K SEA +Q +  +K+  S+V ++E+   
Sbjct: 26454 KVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKK 26513

Query: 3966  DVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPI 4025
                       V +  ++TS    E  +   ++       M +     G+ L+ K      
Sbjct: 26514 SAATSLEKSIVHEEITKTSQAS-EEVRTHAEIKAFST-QMSIN---EGQRLVLKANIAGA 26568

Query: 4026  YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIE 4085
              D  +V      V   +S EY      + G D+T  + + + +     D  +   +  I 
Sbjct: 26569 TDVKWV---LNGVELTNSEEY---RYGVSGSDQTLTIKQASHR-----DEGI---LTCIS 26614

Query: 4086  KIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWL 4145
             K +E     Q       E S A   P F+S P +  + EG+   F C ++G P P + W 
Sbjct: 26615 KTKEGIVKCQYDLTLSKELSDA---PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWF 26671

Query: 4146  LNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIP 4201
              N   I   S   ++    +Y  +I      D+GK  +              L V+P
Sbjct: 26672 KNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLP 26728



 Score = 88.2 bits (209), Expect = 6e-16
 Identities = 66/224 (29%), Positives = 96/224 (42%), Gaps = 12/224 (5%)

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDF 4457
            E   E  ++    P+F  K    +  E    RF+++  G P+P   W+ +   I N    
Sbjct: 1398 EETDESQLERLYKPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTH 1457

Query: 4458 Q--IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
            +  I    T+S++I+      DS  +  VA+NR G +  S  L VE    Q     V P 
Sbjct: 1458 KVVIKEDGTQSLIIV-PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQ-----VKPM 1511

Query: 4516 FTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLI 4573
            F    +NVN+  G  + +  + TG    D+ WLKN   + P    KI  E   G   L I
Sbjct: 1512 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKI 1571

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                 QDS  Y   AIN AG  R    C V++     +P+P+ K
Sbjct: 1572 DSTVSQDSAWYTATAINKAG--RDTTRCKVNVEVEFAEPEPERK 1613



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 77/263 (29%), Positives = 112/263 (42%), Gaps = 19/263 (7%)

Query: 1699 RHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            R  A  E+    P     +K++ V E ++   E  +   G P   V W R    IE+S  
Sbjct: 885  RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSID 942

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
                   G   L ++    EDSG +TC A+NE G   TS  L VQ   S + E +  +  
Sbjct: 943  FQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--VSEEFEKETTAVT 1000

Query: 1819 QKIQQLED---SSRYQRREDVEVAVNQ-------APRFITQLNGPTKLSEGQSAHYECRI 1868
            +K    E     SR     D  +   Q       AP FIT+     KL EG S  + C++
Sbjct: 1001 EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQV 1059

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTS--NDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
               P P+  V W  +G  L +G+RY+ S     G   L I   + +D+GEYT    N  G
Sbjct: 1060 GGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG 1117

Query: 1927 QAVSSIRLNVQSKESIIRDSQHE 1949
            +  +S  L  ++   ++  SQ E
Sbjct: 1118 ETSASASLLEEADYELLMKSQQE 1140



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 128/538 (23%), Positives = 211/538 (39%), Gaps = 93/538 (17%)

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            ++T    +  PP+       + +     A F C +I       ++ W+   + L TG + 
Sbjct: 3182 SVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAMISGRPQP-KISWYKEEQLLSTGFKC 3239

Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            K ++D     L +   +  DA +YTC+A N +G AT S  L V+  + +  + ++P +  
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVY-- 3297

Query: 3667 SGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT 3726
                 I  L++T      +T E +   P RF                   CR   V    
Sbjct: 3298 -PPAIITPLQDT------VTSEGQ---PARF------------------QCR---VSGTD 3326

Query: 3727 MRIDWFHNGRPFATGSRVHTLNDF-GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +++ W+   +     SR   +  F     L+I   Y  D G YT  A N  G  ++TA +
Sbjct: 3327 LKVSWYSKDKKIKP-SRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANL 3385

Query: 3786 TCSAKRDIV---LESQLPQGM------------SGEKIKELERGRISDAPK---EEPIV- 3826
            +  A   I+   +E ++   M             G    EL+  +I++  +   E P+  
Sbjct: 3386 SLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYP 3445

Query: 3827 --------STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878
                     T P FI ++ +  +  S G      V     PK +I+W+ NG LL     Y
Sbjct: 3446 TKFDSEKEGTGPIFIKEVSNADI--SMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADY 3503

Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938
            + V+D    SL IL+   ED GEY C A ND+G+    A +           N    G K
Sbjct: 3504 KFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI---------NSKGEGHK 3554

Query: 3939 RSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLA 3998
             +E  + +  +++K                   PP F+ +++       +    FE  + 
Sbjct: 3555 DTETESAVAKSLEKLGGPC--------------PPHFLKELKPIRCAQGLPAI-FEYTV- 3598

Query: 3999 PVGDPNMKVEWFFNGKPLLHKNRFTPIYD-FGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             VG+P   V WF   K L     +T I++  G           EDSG Y+C+A N+ G
Sbjct: 3599 -VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG 3655



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 91/384 (23%), Positives = 165/384 (42%), Gaps = 44/384 (11%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            + +    V E E ARFE E   + +    W  +   +  +PD +I        L++    
Sbjct: 5614 RPLHSVEVMETETARFETEISEDDIHA-NWKLKGEALLQTPDCEIKEEGKIHSLVLHNCR 5672

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            ++ +      A N     K SA+L V+ +      G++ P      ++V VT+G+    D
Sbjct: 5673 LDQTGGVDFQAAN----VKSSAHLRVKPRVI----GLLRP-----LKDVTVTAGETATFD 5719

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +++  + I V W   GKK++P  +     E   +TL + +   +D+G+ +     +A +
Sbjct: 5720 CELS-YEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQL----TAKD 5774

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V  P               P E  +PL+D+ V EG      C+ V +    V
Sbjct: 5775 FKTHANLFVKEP---------------PVEFTKPLEDQTVEEGATAVLECE-VSRENAKV 5818

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W+K    I  SK +++        L I +  PED   Y C A +       +  L V  
Sbjct: 5819 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKD----FKTSCNLNVVP 5874

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
            P    ++  L PL D+ V E + A+F+ ++ S+    ++W ++GA I +   + +I +G 
Sbjct: 5875 P----HVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGA 5929

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTA 4798
              +L+I     +D   ++C   TA
Sbjct: 5930 VRILVINKCLLDDEAEYSCEVRTA 5953



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 116/517 (22%), Positives = 208/517 (40%), Gaps = 48/517 (9%)

Query: 4307 DKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQK 4366
            D+    T  K + +         E+V E+  + +   K R  +     +   E+   K+ 
Sbjct: 1919 DRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKD 1978

Query: 4367 QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPV-KPSK---------PPIFTKK 4416
            ++ +E++   +      + E TE E KA  +E  +  P  KP K         P IF ++
Sbjct: 1979 ESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIF-ER 2037

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSILIIRQVFV 4475
            +Q   V +   A F V   G+P P  +WY+    I+ S   +          L+IR V  
Sbjct: 2038 IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTA 2097

Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            EDSA     A N  G     A L+V+ K+      ++  +FT   Q+V       +    
Sbjct: 2098 EDSASIMVKAINIAGETSSHAFLLVQAKQ------LI--TFTQELQDVVAKEKDTMATFE 2149

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T    + V W K+G +V    + ++  +   + L IL     D+  Y CV +      
Sbjct: 2150 CETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NV 2208

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
            +  A+ +V                 A  E ++ L+D  V E  + E  C IV       +
Sbjct: 2209 KTTAKLIVE---------------GAVVEFVKELQDIEVPESYSGELEC-IVSPENIEGK 2252

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            WY  D  +K +  + ++       L + +   ED+G+Y  V      + T   K+K  +P
Sbjct: 2253 WYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMK-PRP 2309

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                 +  L  L D  V EG   Q + +++ +    + W+++G  +  +    ++ +  +
Sbjct: 2310 -----IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQS 2363

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +LLI +  +ED G ++   T  A  + TS ++ V S
Sbjct: 2364 HMLLIEDMTKEDAGNYS--FTIPALGLSTSGRVSVYS 2398



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 73/261 (27%), Positives = 114/261 (43%), Gaps = 14/261 (5%)

Query: 3803 MSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            + G + K  E  R+  AP E P+  TPP  ++ +K+ TV E E V  EC +     P   
Sbjct: 873  LHGREAKVTETARVP-APVEIPV--TPPTLVSGLKNVTVIEGESVTLECHISGYPSPT-- 927

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            + WYR    + S   ++  +  G   L I   +AEDSG + C AVN+ G   T   ++ +
Sbjct: 928  VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987

Query: 3923 KLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQ 3982
               +   +         +E    +E+     T +  LTE+      +   P F+T+   Q
Sbjct: 988  VSEEFEKETTAVTEKFTTEEKRFVESRDVVMT-DTSLTEEQA-GPGEPAAPYFITKPVVQ 1045

Query: 3983 TSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD--FGYVAMNFGWVYP 4040
              LVE  +  F CQ+   G+P   V W  +G PL    R+   Y+   G   +     + 
Sbjct: 1046 -KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFA 1102

Query: 4041 EDSGEYLCRATNLYGMDETKA 4061
            +D+GEY     N +G  ET A
Sbjct: 1103 DDAGEYTIVVRNKHG--ETSA 1121



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 151/731 (20%), Positives = 278/731 (38%), Gaps = 78/731 (10%)

Query: 1529  EVSCRLTCRSTTDIVRSTQNEAGLE-QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNV 1587
             EV  ++T   T + + S ++ A  E +   LE++S   ++      TT A    T  +++
Sbjct: 26016 EVKSQMT--ETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSM 26073

Query: 1588  EIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDS 1647
              + EG+ A F        +    V W    + L + +R   T        +I S    D 
Sbjct: 26074 TVYEGESARFS--CDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDE 26131

Query: 1648  GTYTCRAINALGEAVTSGIAIVH----SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQ 1703
             G Y+    N+ G+        +     ++K++    + +   PR+   E     +R  + 
Sbjct: 26132 GNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSP 26191

Query: 1704  D-----------------EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL---- 1742
             +                 E +   PV + P K  +  + +A+   A+L  V +  +    
Sbjct: 26192 EPSHPKAVSPTETKPTPREKVQHLPV-SAPPKITQFLKAEASKEIAKLTCVVESSVLRAK 26250

Query: 1743  RVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
              V W ++G  ++ +      +   G   L +  +   D G Y C    E G + T+    
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26310

Query: 1802  VQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVA--VNQAPRFITQLNGPTKLSEG 1859
              Q+  S+  +    S  +K  Q    S   R+ + +    ++  P  +T L   T +S  
Sbjct: 26311 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSSD 26369

Query: 1860  QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
               A +  +    P P     W  +GK +  G +Y+ S D G   L+I      DSG YTC
Sbjct: 26370 SVAKFAVKATGEPRPT--AIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 26427

Query: 1920  KAINNLGQAVSSIRLNVQS--------------------KESIIRDSQHESAL--EKIQY 1957
                N+ G   SS +L +++                    K++++++   + AL  E+I+ 
Sbjct: 26428 TVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKM 26487

Query: 1958  LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVT--EGHPVHLEATLTPVNDPTMR----V 2011
              E  S+ K A+++++    K    + +K +  T  E   VH E T T      +R    +
Sbjct: 26488 SEAKSQEKLALKEEA---SKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEI 26544

Query: 2012  EWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
             + +     + +G R     +    A D+ +      G  +   +      V+ S   +  
Sbjct: 26545 KAFSTQMSINEGQRLVLKANIA-GATDVKWVL---NGVELTN-SEEYRYGVSGSDQTLTI 26599

Query: 2072  KSGLYLDTLDEQRLKKIQE-LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFE 2130
             K   + D      + K +E + K +    + +E     P F++   S +N+ EG    F 
Sbjct: 26600 KQASHRDEGILTCISKTKEGIVKCQYDLTLSKEL-SDAPAFISQPRS-QNINEGQNVLFT 26657

Query: 2131  CRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKL 2190
             C +    +P   I+WF N   I        +      +L+I      DSG Y  KA N  
Sbjct: 26658 CEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFR 26715

Query: 2191  GEAVNTCTLKV 2201
             G+   T +L V
Sbjct: 26716 GQCSATASLMV 26726



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 138/665 (20%), Positives = 251/665 (37%), Gaps = 59/665 (8%)

Query: 784   EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
             EG +A F        +P   V W + G+ ++ S+R          +  I  ++A D G+Y
Sbjct: 26077 EGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 26134

Query: 844   TVRAVNKLG--EAISTASIRVA--ARSTVTADLGI--PEQRRYIEKTXXXXXXXXXXXXX 897
             +V   N  G  EA  T +I+ A      VT+   +  PE R    +              
Sbjct: 26135 SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPS 26194

Query: 898   XXXXVPESTQKPEFKTPIKD-QISI--KEGGFAHFEARLE------PIGDSTLR---VEW 945
                 V  +  KP  +  ++   +S   K   F   EA  E       +  S LR   V W
Sbjct: 26195 HPKAVSPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTW 26254

Query: 946   LKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
              KDG+ ++ +      ++  G   L I ++T  D G Y C      G + T+        
Sbjct: 26255 YKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAF 26314

Query: 1005  KDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK--ITQKPRFLGPLKGTNKIVEGQSAH 1062
             K I  +       +K       S  +++TE +    I+ KP  +  L+ T  +     A 
Sbjct: 26315 KSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSSDSVAK 26373

Query: 1063  FEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
             F   V+   +   T  W  +GK IT   + +   D G   L+I      DSG+YT   +N
Sbjct: 26374 FA--VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKN 26431

Query: 1123  AAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQI-EEISKSKPVFVQ 1181
             +AG    S  +T++     +   +     +KT  I   K      +I ++  +S+ + + 
Sbjct: 26432 SAGSVSSSCKLTIKAIKDTEAQKVST---QKTSEITPQKKAVVQEEISQKALRSEEIKMS 26488

Query: 1182  PLSNPPPVS---EGKNIHLECRLEPMGDPTMRVEWFHNGRSVT--VGSRFKTYYDFGFVA 1236
                +   ++   E   + +   ++     ++     H   + T       +T+ +    +
Sbjct: 26489 EAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS 26548

Query: 1237  LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
               +    S + G+  V   N  G+     ++  +E ++           +Q   ++ A+ 
Sbjct: 26549 TQM----SINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASH 26604

Query: 1297  R----------TKQ----VREDITVMQ----APQFSRALHNIETVEGTNVHLECRLQPVG 1338
             R          TK+     + D+T+ +    AP F     +    EG NV   C +   G
Sbjct: 26605 RDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEIS--G 26662

Query: 1339  DQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSC 1398
             + +  +EWF N  PI        +   +  +L++ +    DSG YT +A N  G+   + 
Sbjct: 26663 EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 26722

Query: 1399  ALRVI 1403
             +L V+
Sbjct: 26723 SLMVL 26727



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 59/199 (29%), Positives = 85/199 (42%), Gaps = 5/199 (2%)

Query: 4409  KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSI 4467
             +PP FT  +     +  E  RF V     P P + WY+    IK   + + +TF S K +
Sbjct: 25191 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGL 25250

Query: 4468  --LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
               L I  V  +D A +  VA N+ G   C A L V           + P F     N   
Sbjct: 25251 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-TLHPPPTDSTLRPMFKRLLANAEC 25309

Query: 4526  TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKY 4584
               GQ V  + +V+G  P  + W K+G+ +      +I+ E    Y L I +  P+D+G Y
Sbjct: 25310 QEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25369

Query: 4585  ECVAINSAGEARCDAECVV 4603
                A N+AG   C A   V
Sbjct: 25370 RVTATNTAGSTSCQAHLQV 25388



 Score = 85.0 bits (201), Expect = 6e-15
 Identities = 76/283 (26%), Positives = 125/283 (44%), Gaps = 22/283 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            VE+ V   P  ++ L   T + EG+S   EC I  YP P   V WY     ++S   ++ 
Sbjct: 890  VEIPVTP-PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQI 945

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            +   G A L I   + EDSG +TC A+N  G   +S  L VQ  E    + +  +  EK 
Sbjct: 946  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF--EKETTAVTEK- 1002

Query: 1956 QYLEDDSRYKRA----VQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPV------N 2005
             +  ++ R+  +    + D S   E+   G+P     +T+     L    + V       
Sbjct: 1003 -FTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1061

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYD--FGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            +P   V W  +G P+  G+R+K +Y+   G   L I   +A+D G Y     N  GE   
Sbjct: 1062 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSA 1121

Query: 2064 TSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPG 2106
            ++S+  +A   L + +  ++ L + Q     + P+ + E  PG
Sbjct: 1122 SASLLEEADYELLMKS-QQEMLYQTQVTAFVQEPE-VGETAPG 1162



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 67/227 (29%), Positives = 98/227 (43%), Gaps = 7/227 (3%)

Query: 4315 AKSMAQRYEDNLDQ-TEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVV 4373
            A S AQ+   ++   T + +E RV+ + T  P+ P       +  E  V  +K+    + 
Sbjct: 802  ATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSIT 861

Query: 4374 GDKEITRKITSTETTEIEHKAQTQERVVEGPVK-PSKPPIFTKKMQPCRVFEHEQARFEV 4432
            G    T +    E         T+   V  PV+ P  PP     ++   V E E    E 
Sbjct: 862  GT---TVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
               G P P + WYRE++ I++S DFQI   S  + L+IR+ F EDS  F   A N  GT 
Sbjct: 919  HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 978

Query: 4493 KCSANLVVE-EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
              S  L V+  +  +     V   FT T +   V S  +V  DT +T
Sbjct: 979  STSCYLAVQVSEEFEKETTAVTEKFT-TEEKRFVESRDVVMTDTSLT 1024



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 88/379 (23%), Positives = 159/379 (41%), Gaps = 28/379 (7%)

Query: 4360 VHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQP 4419
            V V+++ + +   V +K  T +    E+ ++     +      GP +P+ P   TK +  
Sbjct: 986  VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQ 1045

Query: 4420 CRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSILIIRQVFVED 4477
             ++ E     F  +  G P P + W +   P+     +++  +  + +  L+I   F +D
Sbjct: 1046 -KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADD 1104

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            +  +  V  N+ G    SA+L+ E         ++  S         VT+   V+ + +V
Sbjct: 1105 AGEYTIVVRNKHGETSASASLLEEADYE-----LLMKSQQEMLYQTQVTA--FVQ-EPEV 1156

Query: 4538 TGTKPIDVY--WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
              T P  VY  + K  +K Q  IR K+ ++      +++  Y +D  ++   +       
Sbjct: 1157 GETAPGFVYSEYEKEYEKEQALIRKKMAKDT-----VVVRTYVEDQ-EFHISSFEERLIK 1210

Query: 4596 RCDAECV-VSLPATKDKPKPQTKAAN-APPEIIEP-----LKDKIVAEGQAIEFSCKIVG 4648
              +   +  +L    ++   +  A + +  E +E      +K+  + EG  + F CK+ G
Sbjct: 1211 EIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSG 1270

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             PLP + WYK  K IK  + +QM    D   +LRI    PEDEG Y   A N  G    +
Sbjct: 1271 YPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICS 1330

Query: 4708 AKLKVTQPDQADNLPALTP 4726
             KL V +P      P   P
Sbjct: 1331 GKLYV-EPAAPLGAPTYIP 1348



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 130/523 (24%), Positives = 202/523 (38%), Gaps = 72/523 (13%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PPQ +  L+ VT   G    F   I   G P  KI W K  Q +    +   +      +
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAMIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3249

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L ++    +D+  YTC A +  GVA T A L V          + PE +   Q++  Y  
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQEMPVYP- 3298

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                          P  I PLQD     EG+ A F+ +   VS   ++V WY   + I  
Sbjct: 3299 --------------PAIITPLQDT-VTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 3340

Query: 816  SS--RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV---TA 870
            S   R+T  F   Y  L I     ED G+YT  A N +G+  STA++ + A  ++     
Sbjct: 3341 SRFFRMTQ-FEDTY-QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERI 3398

Query: 871  DLGIP-EQRRYIEKTXXXXXXXXXXXXXXXXXVPES----TQKPEFKTPIKDQ------I 919
            +  I  E + +                     + E+    ++ P + T    +      I
Sbjct: 3399 EQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPI 3458

Query: 920  SIKEGGFAHFE------ARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKS 973
             IKE   A           +  IG    +++W  +G  +  S+     F+    +L I  
Sbjct: 3459 FIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF 3518

Query: 974  VTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRT 1033
              + D G YTC A N  G+   SA L I +K +   +++    + K             +
Sbjct: 3519 TKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK-------------S 3565

Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI-TSANRI 1092
             E++     P FL  LK   +  +G  A FE  V    +   TV W+   KQ+ TS    
Sbjct: 3566 LEKLGGPCPPHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYT 3622

Query: 1093 QTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              ++  G     +   + EDSG+Y   A N  GE+  +A + V
Sbjct: 3623 IIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 97/427 (22%), Positives = 171/427 (40%), Gaps = 49/427 (11%)

Query: 4387 TTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T E+  +A   +      VK   P IF   +   +VFE ++A+FE E   EP    +W +
Sbjct: 5320 TGEVSFQAANAKSAANLKVK-ELPLIFITPLSDVKVFEKDEAKFECEVSREP-KTFRWLK 5377

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
                I     F++    TK  ++I+    ED A +   AE++  + K    L++E  R +
Sbjct: 5378 GTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGK----LIIEGIRLK 5433

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
                     F    ++V     +      +++    I V W KN +++       + +E 
Sbjct: 5434 ---------FLTPLKDVTAKEKESAVFTVELSHDN-IRVKWFKNDQRLHTTRSVSMQDEG 5483

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
             T+++   +    D+ +    A+  + EA+                          P   
Sbjct: 5484 KTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTV-------------------LEGDPYFT 5524

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              L+D    E   +   C+I     P V+W+K  K IKPSK   +     +  L + +A 
Sbjct: 5525 GKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKTDGKKRMLILKKAL 5583

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
              D G Y C      G    + KL +   +    +  + PL  + V E + A+F+T+I S
Sbjct: 5584 KSDIGQYTC----DCGTDKTSGKLDIEDRE----IKLVRPLHSVEVMETETARFETEI-S 5634

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
            +      W  +G  + +TPD ++  EG    L++ N   + TG    +    A  V++SA
Sbjct: 5635 EDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQ----AANVKSSA 5690

Query: 4807 KLVVKSK 4813
             L VK +
Sbjct: 5691 HLRVKPR 5697



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 95/417 (22%), Positives = 164/417 (39%), Gaps = 45/417 (10%)

Query: 70    SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
             S P+     ++   +    AKF  K  G P P   WT+    + +  KY +  +E  G  
Sbjct: 26353 SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL--SEDKGGF 26410

Query: 130   SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
              L I +    D G YTCT +N  G    S  +  +               +  SE    K
Sbjct: 26411 FLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVST---QKTSEITPQK 26467

Query: 190   AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREV--SFRESITKRYVGE 247
                 Q   ++++ +++++  +           K +  +  +  EV  S   S+ K  V E
Sbjct: 26468 KAVVQEEISQKALRSEEIKMSEAKSQEKLA-LKEEASKVLISEEVKKSAATSLEKSIVHE 26526

Query: 248   SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307
                +I+     S    +  +I        + EG     +  ++G     V W  NG  L 
Sbjct: 26527 ---EITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVELT 26581

Query: 308   NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
             NS ++    + +  TL ++     D G  T        CI         S T+  +   +
Sbjct: 26582 NSEEYRYGVSGSDQTLTIKQASHRDEGILT--------CI---------SKTKEGIV--K 26622

Query: 368   SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
              QY     +       E+S+   AP F+   + +++ EG+   F C ++G P PE+ WF 
Sbjct: 26623 CQYDLTLSK-------ELSD---APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK 26672

Query: 428   NDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             N+  I    N  + ++ S N ++L I N ++SDSG  T  A+N  G+ +    L V+
Sbjct: 26673 NNLPISISSN--VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 71/236 (30%), Positives = 106/236 (44%), Gaps = 17/236 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP  +  LK+VT +EG  +  E  I   G P+  + W +    IE+S  F   F+ G   
Sbjct: 896  PPTLVSGLKNVTVIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIAR 953

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIER-TSQHPE--TLQYIQQLED 752
            L +     +DSG +TC AV+  G   T   L V      E+ T+   E  T +  + +E 
Sbjct: 954  LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013

Query: 753  YSKYQHQESIEEQTS-----QRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
                    S+ E+ +       P FI +P+  + +L EG +  F  Q+    +P   V W
Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVEGGSVVFGCQVG--GNPKPHVYW 1069

Query: 807  YKDGRPITASSRITSIFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
             K G P+T   R    +N   G   L I    A+DAG YT+   NK GE  ++AS+
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 88/347 (25%), Positives = 143/347 (41%), Gaps = 29/347 (8%)

Query: 242  KRYVGESDVQIS-TEI-DRSLGPVSP--PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
            KR+V   DV ++ T + +   GP  P  P    KP   KL EG    F  Q+ GNP+P V
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067

Query: 298  TWFKNGQRLINSNKHEIITTHNHTT----LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
             W K+G  L    ++++  ++N  T    L +  T   D+G YT++  N +G    S  L
Sbjct: 1068 YWKKSGVPLTTGYRYKV--SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125

Query: 354  AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
              E+  E  ++ Q+ + +  TQ     +  E+ E   AP FV    +++    K      
Sbjct: 1126 LEEADYELLMKSQQ-EMLYQTQVTAFVQEPEVGE--TAPGFVYSEYEKEYE--KEQALIR 1180

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
            +   +    V  ++ D++       + L+ E       I   TL +          + GE
Sbjct: 1181 KKMAKDTVVVRTYVEDQEFHISSFEERLIKEI---EYRIIKTTLEE-------LLEEDGE 1230

Query: 474  TAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
               +  +++ E E  V   F  R     + EG  V  + +  G P P+I W KDG  I  
Sbjct: 1231 E--KMAVDISESE-AVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKH 1287

Query: 534  NPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
                ++     G ++L IP     D   Y   A N+ G+     +LY
Sbjct: 1288 GERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLY 1334



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 56/208 (26%), Positives = 92/208 (44%), Gaps = 11/208 (5%)

Query: 371   ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430
             IT T Q   E R     KA + Q         + EG+       + G    +V W +N  
Sbjct: 26528 ITKTSQASEEVRTHAEIKAFSTQM-------SINEGQRLVLKANIAGAT--DVKWVLNGV 26578

Query: 431   QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490
             ++ +   ++  V+ S +  L I   +  D G++TC+++ K G    Q  L  + KE   A
Sbjct: 26579 ELTNSEEYRYGVSGS-DQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDA 26636

Query: 491   PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
             P F+ +  + N+ EG+ V+      G P+P I W K+ +PI  +  + I       +L+I
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26696

Query: 551   PRAKASDAAWYQCTAQNVAGSTATRARL 578
               A  SD+  Y   A+N  G  +  A L
Sbjct: 26697 RNASVSDSGKYTIKAKNFRGQCSATASL 26724



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 23/262 (8%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP++ Q+ +   +Q G  A+F   +SG P+P+++W+K  Q L    K + +      TL 
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +      D+  YT  A+N  G   TS  L+VE P E    DQ                  
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP-EVVSPDQEM---------------- 3294

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P  +   QD   +EG+  RF CRV+G    +V+W+  D++I+     ++   E
Sbjct: 3295 ---PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
               + L I      D G  T VA N  G+ +    L++   E ++  + +E+   + ++E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHER-IEQEIEMEMKE 3408

Query: 505  GEPVVLNARAVGTPTPRITWQK 526
                 L+A   G  +  +   K
Sbjct: 3409 FSSSFLSAEEEGLHSAELQLSK 3430



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 71/248 (28%), Positives = 106/248 (42%), Gaps = 22/248 (8%)

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIV----PPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            E    +++     V   K ++  GG++    P   T     V+   G +V L T +T  K
Sbjct: 4212 EKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAK 4270

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD-SGKYECVAINSAGEARCDAE 4600
              +V W    K V  D + K L++  TYTL+I +   +D  G+Y C A+N +G+    A+
Sbjct: 4271 --EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAK 4328

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V             +AA      IEPL+   VA G   +F+C+I   P    QW+K  
Sbjct: 4329 LTVV-----------KRAAPVIKRKIEPLE---VALGHLAKFTCEIQSAPNVRFQWFKAG 4374

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            + I  S    +  +    +L I      D G+Y C A N  G V+  A L VT P     
Sbjct: 4375 REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKK 4434

Query: 4721 LPALTPLR 4728
            +  L P R
Sbjct: 4435 VRKLLPER 4442



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 101/479 (21%), Positives = 192/479 (40%), Gaps = 41/479 (8%)

Query: 2243  RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
             R +T+ R  T V+EG++A F C  +   +P   + +   G+ L ++AR  +T      + 
Sbjct: 26065 RILTKPRSMT-VYEGESARFSCDTDG--EPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF 26121

Query: 2303  DIQHCVPEDAGEYSVKAINALGHCTSAISMT----------VTAKGSIISESQR---PEG 2349
             +I      D G YSV   N+ G   +  ++T          VT+   + S   R   PE 
Sbjct: 26122 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 26181

Query: 2350  LEKIRELESAEPFK----RPEIPEPVTRQR----PVFTQPLQNIDNIQEGQTAHFDCRLI 2401
             ++  + ++S EP       P   +P  R++    PV   P   I    + + +    +L 
Sbjct: 26182 VKSPKRVKSPEPSHPKAVSPTETKPTPREKVQHLPVSAPP--KITQFLKAEASKEIAKLT 26239

Query: 2402  PVGDPTL----KVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNL 2456
              V + ++    +V W+++ K ++++      +   G   + I+++ + D+G Y+C  S  
Sbjct: 26240 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGE 26299

Query: 2457  LGEXXXXXXXXXXXXXXIQLETQH-PEGMKKIQKLEQPHERRSEEPDREFEKPIFTQ--V 2513
              G               I  +     E  K  QK  +    R  EP  +  +PI ++  +
Sbjct: 26300 GGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP--KAPEPISSKPVI 26357

Query: 2514  LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSV 2573
             +TG  +      +  +  V   G+P     W  +G  +  G +++ + D G   L+I+  
Sbjct: 26358 VTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKT 26417

Query: 2574  VANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMF 2633
               +D+GLY C   N AG                  Q +  +   +I  ++ A+  V E  
Sbjct: 26418 DTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAV--VQEEI 26475

Query: 2634  VDTGVQQAPIFTTHLKSYDKLV---EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA 2689
                 ++   I  +  KS +KL    E   V +  +V+     +L+       +T T+ A
Sbjct: 26476 SQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQA 26534



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 82/333 (24%), Positives = 143/333 (42%), Gaps = 40/333 (12%)

Query: 2924  VEGQVLHLEGQ--------VEPKN-DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLV 2974
             V GQ++H  G+         + +N D   ++ WYF  + LE   ++++T + G   L + 
Sbjct: 25073 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVK 25132

Query: 2975  DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRK 3034
             D+ + D G Y CK  N  GE  + + ++      + +   + + T  ++KI+   D++R 
Sbjct: 25133 DITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYD--YYCRRT--MKKIKRRTDTMRL 25188

Query: 3035  EPGQQPDDDTGRPPEFT-TVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA 3093
                        RPPEFT  ++     + E    +    +  T      + W+ +G+ I+ 
Sbjct: 25189 ---------LERPPEFTLPLYNKTAYVGE----NVRFGVTITVHPEPHVTWYKSGQKIKP 25235

Query: 3094  SHRIRTVYAF----GMVVLEILGTKTTDSGTYSCRATNKWGQ----AEISVKLECVDKSK 3145
                 +  Y F    G+  L I    T D   Y+  A NK+G+    A+++V L       
Sbjct: 25236 GDNDKK-YTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDS 25294

Query: 3146  GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD-F 3204
               +P F   + N E  ++GQS  FE  V  +  P +K  W  +GQP+     I+ + +  
Sbjct: 25295 TLRPMFKRLLANAE-CQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGL 25351

Query: 3205  GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
              +  L I  T   D+G Y   A N  G    +A
Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQA 25384



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 65/233 (27%), Positives = 101/233 (43%), Gaps = 16/233 (6%)

Query: 262   PVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
             PVS PPKI Q  +    +E A     V+ S      VTW+K+G++L  +   +   + + 
Sbjct: 26216 PVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26275

Query: 321   T-TLRVRNTQKSDSGHYTLLAENPNGCIVT----------SGYLAVESPTESYVQDQRSQ 369
             T  L++ N  +SD G Y        G   T          S +  V   +E+   DQ++ 
Sbjct: 26276 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26335

Query: 370   YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIND 429
               T T++ E +    IS K   P  V   QD  V+   + +F  + TG P P   W  + 
Sbjct: 26336 ESTVTRKTEPKAPEPISSK---PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDG 26392

Query: 430   RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             + I     +K L  + G   L I     SDSG+ TC  +N +G  +  C+L +
Sbjct: 26393 KAITQGGKYK-LSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 100/385 (25%), Positives = 155/385 (40%), Gaps = 60/385 (15%)

Query: 2904 PDTEYPK-PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            PD E P  P  II    +    EGQ    + +V   +  DLK+ WY   K ++    F++
Sbjct: 3290 PDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRM 3346

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLI-ERTQHP----- 3016
            T       L++ + Y  D G YT  A N  G+  +++ +   + ++++ ER +       
Sbjct: 3347 TQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEM 3406

Query: 3017 ---------KGTEGLE-------KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI--V 3058
                        EGL        KI    + L + P      D+ +        K++   
Sbjct: 3407 KEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNA 3466

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            DIS G +A    ++I  G     I+WF+NG  +  S   + V+      L IL TK  D 
Sbjct: 3467 DISMGDVATLSVTVI--GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDE 3524

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQK--------------------PRFTTHIQNI 3158
            G Y+C A+N +G+   S  L+   K +G K                    P F   ++ I
Sbjct: 3525 GEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPI 3584

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS---TRIKTVSDFG-FVVLDIAYT 3214
                 G  A FE TV  V +P   + W+   + +  S   T I   +  G F+V D    
Sbjct: 3585 R-CAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVND---P 3638

Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATI 3239
            Q  DSG Y+C+A N  GE    A +
Sbjct: 3639 QREDSGLYICKAENMLGESTCAAEL 3663



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 53/209 (25%), Positives = 97/209 (46%), Gaps = 21/209 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P  I+ + +  ++ G     S  ++G P P +QW+    L+ PS  ++     D+++L I
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-----------TQPDQADNLPAL------- 4724
                 EDEG+Y C+A N  G+   +A LK+           T+   A +L  L       
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576

Query: 4725 --TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIG 4781
                L+ I   +G PA F+  +  +  PT+ W +E   +  +  + +IH  N +   ++ 
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3636

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED+G + C+A    G+   +A+L+V
Sbjct: 3637 DPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 97/373 (26%), Positives = 160/373 (42%), Gaps = 46/373 (12%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            W ++   I+ SP  +         L I  V + D+  +  V          +A LVVEE 
Sbjct: 4654 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE- 4712

Query: 4504 RRQGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                    +P  F  T  + V V  GQ + L  ++   K  DV W K+GK V       +
Sbjct: 4713 --------LPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIV 4762

Query: 4563 LEEDGTY-TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
                G    L I +A   D+G Y  V + +A    C + CV  +   +D           
Sbjct: 4763 PGVIGLMRALTINDADDTDAGTY-TVTVENANNLEC-SSCVKVVEVIRD----------- 4809

Query: 4622 PPEIIEPLKDK-IVAEGQAIEFSCKIVGKPLPTVQWYKG-DKL-IKPSKYFQMSRTADEY 4678
               +++P++D+ +  +G AI F+C I  K  P ++W+KG D++  +P+   ++ R  +  
Sbjct: 4810 --WLVKPIRDQHVKPKGTAI-FACDI-AKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHL 4865

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
             L+I  A PED  +Y   A    G+    AKL + + +    +  L P+ D+ +YE + A
Sbjct: 4866 YLKIKNAMPEDIAEY---AVEIEGK-RYPAKLTLGERE----VELLKPIEDVTIYEKESA 4917

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
             F  +I+    P  QW  +G L+  +P  ++  EG    L +     +  G    +A  A
Sbjct: 4918 SFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNA 4976

Query: 4799 AGQVETSAKLVVK 4811
                 T+A L VK
Sbjct: 4977 I----TTAILTVK 4985



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 94/350 (26%), Positives = 148/350 (42%), Gaps = 53/350 (15%)

Query: 1191  EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
             EG ++   C++E   D + +V W+   R +    +++  Y+ G   L +   T  D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 1251  TVRAVNHLG--SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVM 1308
               + VN  G  S++    V+ +     V D    + +++I+      RRT  +R    + 
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVRE---VYDYYCRRTMKKIK------RRTDTMR---LLE 25190

Query: 1309  QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP-AYEFD- 1366
             + P+F+  L+N     G NV     +    +    V W+ +G+ IK G   +   +E D 
Sbjct: 25191 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDK 25248

Query: 1367  -YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
                 L + SV  +D   YT  A N+ GE   SC     AK  + L   HP          
Sbjct: 25249 GLYQLTINSVTTDDDAEYTVVARNKYGE--DSCK----AKLTVTL---HP---------- 25289

Query: 1426  DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485
                    TD      T++P F  R  +     EGQ V FE ++  +    LK  W K+GQ
Sbjct: 25290 -----PPTD-----STLRPMF-KRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQ 25336

Query: 1486  PVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
             P+++G     IH+   Y AL I D + ED+G Y   A N  G+      L
Sbjct: 25337 PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHL 25386



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 51/206 (24%), Positives = 96/206 (46%), Gaps = 4/206 (1%)

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSK 4667
            ++  + Q +    P  +++P+  K + EG    F  K+VG+P+P   W+  G +++    
Sbjct: 1398 EETDESQLERLYKPVFVLKPVSFKCL-EGANCRFDLKVVGRPMPETFWFHDGQQIVNDYT 1456

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +  + +     +L I  A P D G++  VA N AGR +++  L V   +       +  L
Sbjct: 1457 HKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKL 1516

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI--PETPDFQMIHEGNNAVLLIGNTYE 4785
            +++ + EG   + K + T    P I WL+   +I   + P  ++      A L I +T  
Sbjct: 1517 KNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVS 1576

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            +D+  +T  A   AG+  T  K+ V+
Sbjct: 1577 QDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 95/397 (23%), Positives = 159/397 (40%), Gaps = 50/397 (12%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F   ++   V E  QARFE     E   +  W +    IK+S  F I     K IL+I  
Sbjct: 4991 FAVPLKDVTVPERRQARFECVLTREANVI--WSKGPDIIKSSDKFDIIADGKKHILVIND 5048

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
               +D  V+ A  E +    K SA L V   R +         F    ++  V  G+   
Sbjct: 5049 SQFDDEGVYTAEVEGK----KTSARLFVTGIRLK---------FMSPLEDQTVKEGETAT 5095

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
               +++  K + V W KN  K+       I  E  T+ L + E           V ++  
Sbjct: 5096 FVCELSHEK-MHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKE-----------VTLDDI 5143

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
             + +     V  L +T      Q K   A P     L DK   E   I   C+ V K +P
Sbjct: 5144 SQIKAQ---VKELSSTA-----QLKVLEADPYFTVKLHDKTAVEKDEITLKCE-VSKDVP 5194

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             V+W+K  + I PS  + +        L+I +A  +D+G+Y C       +  V  + ++
Sbjct: 5195 -VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARL 5253

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI--QWLREGALIPETPDFQMI 4770
             + ++        PL  + V+ G+ A F+ +++   +P +  QW  +G  +  +PD ++I
Sbjct: 5254 IEVEK--------PLYGVEVFVGETAHFEIELS---EPDVHGQWKLKGQPLTASPDCEII 5302

Query: 4771 HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             +G   +L++ N     TG  + +A  A        K
Sbjct: 5303 EDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVK 5339



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 78/308 (25%), Positives = 130/308 (42%), Gaps = 41/308 (13%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
            GR  +         ++VNV  G    L+ KV+      V W  N ++++PD R + + + 
Sbjct: 2392 GRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2451

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
                L+I   +  D G Y+ +        R +  C +S+   K               II
Sbjct: 2452 TKQRLVINRTHASDEGPYKLIV------GRVETNCNLSVEKIK---------------II 2490

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              L+D    E Q + F  ++    +  V W   DK IKPS  +++      Y L +    
Sbjct: 2491 RGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMM 2549

Query: 4687 PEDEGDYKCVAYNS--AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
             +DEG Y   A  +  +G++TVA                  PL D  V E Q A F+ ++
Sbjct: 2550 KDDEGKYTFYAGENMTSGKLTVAGGA------------ISKPLTDQTVAESQEAVFECEV 2597

Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
             +      +WLR+G  +P T + +   +G+   L+I  T  +D G +T +  T+    +T
Sbjct: 2598 ANPDSKG-EWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KT 2652

Query: 4805 SAKLVVKS 4812
            SAKL V++
Sbjct: 2653 SAKLKVEA 2660



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 75/279 (26%), Positives = 113/279 (40%), Gaps = 27/279 (9%)

Query: 3011 ERTQHPKGTEGLE--KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHY 3068
            E +    GTE +   KIQ  E  L KE G          P   T   D V   EG I H 
Sbjct: 4214 EESSSESGTEEVATVKIQEAEGGLIKEDG----------PMIHTPLVDTVS-EEGDIVHL 4262

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD-SGTYSCRATN 3127
              S+    +    + W++  K + +  + + +       L I    T D  G Y C A N
Sbjct: 4263 TTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALN 4318

Query: 3128 KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187
              G+   S KL  V ++    P     I+ +E +  G  A F C +     P+++ +W+ 
Sbjct: 4319 DSGKTATSAKLTVVKRAA---PVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFK 4372

Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG- 3246
             G+ +  S +    S      L+I  TQ  D GEY C+A N+YG     AT+     GG 
Sbjct: 4373 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGE 4432

Query: 3247 VYLESLQPDSLAKIRELESLQGAQQQTP--STPSAEPPK 3283
              +  L P+   + +E   L+   ++ P    P  EP K
Sbjct: 4433 KKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKK 4471



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 109/510 (21%), Positives = 191/510 (37%), Gaps = 51/510 (10%)

Query: 1374  SVYPE--DSGVYTCQATNQLGEAVTSCALRVIAK-----KDLILESQHPSGLE-KIQYLE 1425
             SV+PE   +  Y   +  +  E   S ++R +       ++ +   +H +  E K   LE
Sbjct: 25986 SVFPELTRTEAYAVPSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALE 26045

Query: 1426  DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKN 1483
             + S  +K+       T+  R +T+P+S+  V EG+   F C    EPV      V W + 
Sbjct: 26046 EKSLEEKSTTRKIKTTLAARILTKPRSM-TVYEGESARFSCDTDGEPVPT----VTWLRK 26100

Query: 1484  GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS-------CRLTC 1536
             GQ ++   R +          +I  + A D G Y+    N  G  E          R+T 
Sbjct: 26101 GQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTE 26160

Query: 1537  RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTD-----MVDEVTTQA---------PICTT 1582
             ++ T   R    E  ++  + ++   +    +      V    T+          P+   
Sbjct: 26161 KAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPREKVQHLPVSAP 26220

Query: 1583  SLKNVEIKEGQRAHFERRLIPVSDATLK---VEWYHNNKPLKSGSRFT-ETNNFGFVALD 1638
                   +K        +    V  + L+   V WY + K LK    F    +  G   L 
Sbjct: 26221 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 26280

Query: 1639  IMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQ--LEDTSK 1696
             I +    D G Y C      G + T+   +  + KSI+ +        + +Q   E T  
Sbjct: 26281 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 26340

Query: 1697  YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
              +      E I+  PV    ++D  V+ +  A F  +    G+P+    W ++G  I   
Sbjct: 26341 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKA--TGEPRPTAIWTKDGKAITQG 26398

Query: 1757  NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-------KASLQ 1809
              +     D G   L +   +  DSG YTC   N  G   +S  L +++       K S Q
Sbjct: 26399 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 26458

Query: 1810  LESQHESALQKIQQLEDSSRYQRREDVEVA 1839
               S+     + + Q E S +  R E+++++
Sbjct: 26459 KTSEITPQKKAVVQEEISQKALRSEEIKMS 26488



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 72/298 (24%), Positives = 117/298 (39%), Gaps = 16/298 (5%)

Query: 3513 QGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI---- 3568
            + +  + ++ ++   + GT  +    E   G    +T  A    P E   TP  L+    
Sbjct: 845  KSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLK 904

Query: 3569 ---LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
               + E  S   EC +      S  V W+     + +    +     G   L I   +  
Sbjct: 905  NVTVIEGESVTLECHISGY--PSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAE 962

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ-LPSHFKSGTESIQKLEETLHKREE 3684
            D+G +TC A N  G  + SC L V+  +    E   +   F +  +   +  + +     
Sbjct: 963  DSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTS 1022

Query: 3685 ITIEDEKPNPPRFTVEIKDNI--DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742
            +T E   P  P     I   +   + EGG V F C+V   G+P   + W  +G P  TG 
Sbjct: 1023 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1080

Query: 3743 R--VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
            R  V      G   L I   +A DAGEYT    NK G  + +A +   A  +++++SQ
Sbjct: 1081 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1138



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/282 (24%), Positives = 121/282 (42%), Gaps = 20/282 (7%)

Query: 3667 SGTESIQKLEETLHKREEITIED-------EKPNPPRFTVEIKDNIDVPEGGPVHFDCRV 3719
            +GT   ++  E LH RE    E        E P  P   V    N+ V EG  V  +C +
Sbjct: 861  TGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHI 920

Query: 3720 EPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779
               G P+  + W+       +          G   L I   +A D+G +TC A N+ G+ 
Sbjct: 921  S--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTV 978

Query: 3780 TTTAKITCSAKRDIVLESQ-LPQGMSGEKIKELERGRI--SDAPKEE----PIVSTPPKF 3832
            +T+  +      +   E+  + +  + E+ + +E   +  +D    E    P     P F
Sbjct: 979  STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1038

Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM--GFVSLD 3890
            IT+     + E   V F C+V    +PK  + W ++G  L +G+RY+  Y+   G   L 
Sbjct: 1039 ITKPVVQKLVEGGSVVFGCQVGG--NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLV 1096

Query: 3891 ILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            I   +A+D+GEY     N  GE    A++  +   ++++++Q
Sbjct: 1097 ISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1138



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/271 (25%), Positives = 121/271 (44%), Gaps = 16/271 (5%)

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320
            RE +  + A+   P      PP  ++ +++VT ++EG+S   E  +     P   V W+ 
Sbjct: 876  REAKVTETARVPAPVEIPVTPPTLVSGLKNVT-VIEGESVTLECHISGYPSPT--VTWYR 932

Query: 3321 NGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
               ++     ++     GI  L I   + E+SG + C A N+ G  ST   L     E  
Sbjct: 933  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 992

Query: 3381 ILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKG-----KAPVF-TVPLSNIENLRE 3434
              ++      +   E+ + +E   V   DTS+ EE+       AP F T P+  ++ L E
Sbjct: 993  EKETTAVT-EKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPV--VQKLVE 1049

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSGE 3492
            G +  F  ++     P+  V W  +G  L  G R++   +   G   L IS T+ +D+GE
Sbjct: 1050 GGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1107

Query: 3493 YLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            Y     N +GE   +AS+  +    ++++SQ
Sbjct: 1108 YTIVVRNKHGETSASASLLEEADYELLMKSQ 1138



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 89/373 (23%), Positives = 153/373 (41%), Gaps = 52/373 (13%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E A F+ E   E +P ++WY +   ++ S      +      L +R V +ED+      A
Sbjct: 5714 ETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTA 5772

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
            ++     K  ANL V+E          P  FT   ++  V  G    L+ +V+  +   V
Sbjct: 5773 KD----FKTHANLFVKEP---------PVEFTKPLEDQTVEEGATAVLECEVS-RENAKV 5818

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W KNG ++    + +I+ +     L+I +  P+D   Y C A +   +  C+   V   
Sbjct: 5819 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSCNLNVV--- 5873

Query: 4606 PATKDKPKPQTKAANAPP--EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
                            PP  E + PL D  V E +   F C++  +    V+W+K    I
Sbjct: 5874 ----------------PPHVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEI 5916

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS--AGRVTVAAKLKVTQPDQADNL 4721
            K  K + +        L I++   +DE +Y C    +  +G +TV  +  V   +     
Sbjct: 5917 KKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKN----- 5971

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
                 L +I V E    +   ++ SK    + W +    I ET  ++++ EG   +L+I 
Sbjct: 5972 -----LANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 6025

Query: 4782 NTYEEDTGTFTCR 4794
            N + ED G + CR
Sbjct: 6026 NAHLEDAGNYNCR 6038



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 85/361 (23%), Positives = 147/361 (40%), Gaps = 22/361 (6%)

Query: 513   RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN----V 568
             +A G P P   W KDG  I    + ++  D G   L+I +   SD+  Y CT +N    V
Sbjct: 26377 KATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSV 26436

Query: 569   AGSTATRARLYXXXXXXXXXXQKRLHLPRPTK--VXXXXXXXXXXXXYLRHVE-RARPYI 625
             + S     +            QK   +    K  V             ++  E +++  +
Sbjct: 26437 SSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKL 26496

Query: 626   PPGEE-DRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
                EE  +V    +  V   + T++E   +H     E +   +   E ++    I+A S 
Sbjct: 26497 ALKEEASKVLISEE--VKKSAATSLEKSIVH-----EEITKTSQASEEVRTHAEIKAFST 26549

Query: 685   FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK-AVLHVTPRATIERTSQHPE- 742
               SI     + L        D  ++    V  T   E +  V       TI++ S   E 
Sbjct: 26550 QMSINEGQRLVLKANIAGATDV-KWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26608

Query: 743   TLQYIQQL-EDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPT 801
              L  I +  E   K Q+  ++ ++ S  P FI   +    + EG+N  F  +++   +P+
Sbjct: 26609 ILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQN-INEGQNVLFTCEIS--GEPS 26665

Query: 802   MRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIR 861
               +EW+K+  PI+ SS ++   +    SL I +    D+G YT++A N  G+  +TAS+ 
Sbjct: 26666 PEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLM 26725

Query: 862   V 862
             V
Sbjct: 26726 V 26726



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 67/284 (23%), Positives = 117/284 (41%), Gaps = 17/284 (5%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P F    ++    +G N  F  ++ G P+P + W +   P+   +  S+  +      SL
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV--YSL 26694

Query: 132   LIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
              I+     D G+YT  A+N  G+  A  S+ + P                R   +T    
Sbjct: 26695 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLP-----LVEEPSREVVLRTSGDTSLQG 26749

Query: 190   AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREV--SFRESITKRYVGE 247
             ++ +Q      S+Q    +  + +  SS  + K  +   + +  +  SF E  +  ++G 
Sbjct: 26750 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26809

Query: 248   SDV-QISTEIDRSLGPVS---PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             S++ Q+ +   + L       PPKI   P +  + EG         +G P P VTW   G
Sbjct: 26810 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26869

Query: 304   QRLIN--SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +++ +    +  I  T + TTL + + QK D G YTL   N  G
Sbjct: 26870 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 119/546 (21%), Positives = 211/546 (38%), Gaps = 85/546 (15%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            +Y   A R        V   + P+ L  L+    +  G+ A F A +  +      + WY
Sbjct: 3171 EYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVT-VQSGKPARFCAMISGRPQ--PKISWY 3227

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
               + +++  + +  HD     L +     ED+ VYT  A+N  G A  SAS++VE    
Sbjct: 3228 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV--- 3284

Query: 1141 IDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECR 1200
                                + V P    +E+    P  + PL +    SEG+    +CR
Sbjct: 3285 -------------------PEVVSP---DQEMPVYPPAIITPLQD-TVTSEGQPARFQCR 3321

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
               +    ++V W+   + +     F+         L+I  A   D G YT  A N +G 
Sbjct: 3322 ---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQ 3378

Query: 1261 AHTSAIVRVIERSDIVTDTQNEQAIE-------------QIQLLEDAARRTKQVREDITV 1307
              ++A +  +E  + +   + EQ IE             + + L  A  +  ++ E + +
Sbjct: 3379 VSSTANLS-LEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLEL 3437

Query: 1308 M-QAPQFSRALHN---------IETVEGTNVHL----ECRLQPVGDQTMRVEWFCNGKPI 1353
            + ++P +     +         I+ V   ++ +       +  +G    +++WF NG  +
Sbjct: 3438 LSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLL 3497

Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK----KDLI 1409
                 ++  ++ D  +L +L    ED G YTC A+N  G+ + S  L++ +K    KD  
Sbjct: 3498 TPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTE 3557

Query: 1410 LESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLE 1469
             ES     LEK+                      P F+   K I    +G    FE  + 
Sbjct: 3558 TESAVAKSLEKL-----------------GGPCPPHFLKELKPI-RCAQGLPAIFEYTV- 3598

Query: 1470 PVTDSNLKVEWFKNGQPVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             V +    V WFK  + +     +  IH+  G     + D   EDSG+Y C+A N++G  
Sbjct: 3599 -VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGES 3657

Query: 1529 EVSCRL 1534
              +  L
Sbjct: 3658 TCAAEL 3663



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 97/399 (24%), Positives = 165/399 (41%), Gaps = 52/399 (13%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            KK +     E+    FEV    + +P +KW+ ++  IK S   ++ +      L+++ + 
Sbjct: 2753 KKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNIS 2811

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
              D+  + AV     G  +C A L VE               T T +N+ V   +    +
Sbjct: 2812 PSDAGEYTAVV----GQLECKAKLFVETLH-----------ITKTMKNIEVPETKTASFE 2856

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +V+    +   WLKNG +++   + KI+ +   + L+I+    +DS +Y  V     G 
Sbjct: 2857 CEVSHFN-VPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGN 2911

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V+                 P  I   LKD    E   I F   +  + + + 
Sbjct: 2912 DQVSATLTVT-----------------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SY 2953

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W K    IK +   QM      ++L I      D  DY  V    AG+ T  A L V  
Sbjct: 2954 KWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFV----AGKATSTATLYV-- 3007

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
              +A ++     ++DI V E + A F+ ++ S+   T+QW+++   +  T   ++  E  
Sbjct: 3008 --EARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               LLI +T   D G +T     A G V T AKL V+ +
Sbjct: 3065 VHRLLIPSTRMSDAGKYT---VVAGGNVST-AKLFVEGR 3099



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 56/189 (29%), Positives = 83/189 (43%), Gaps = 6/189 (3%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I  PL D +  EG  +  +  I       V WY  +KL+   + F+  +  + YTL I
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVI 4300

Query: 4683 SEAFPED-EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
             +   ED +G+Y C A N +G+   +AKL V +         + PL    V  G  A+F 
Sbjct: 4301 DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLE---VALGHLAKFT 4357

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +I S      QW + G  I E+    +      + L I  T   D G +TC+A+   G 
Sbjct: 4358 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 4417

Query: 4802 VETSAKLVV 4810
            V  +A L V
Sbjct: 4418 VSCTATLTV 4426



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 147/697 (21%), Positives = 269/697 (38%), Gaps = 67/697 (9%)

Query: 1691  LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
             LE+ S  ++ + +    T A       + + V E ++A F       G+P   V WLR G
Sbjct: 26044 LEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTD--GEPVPTVTWLRKG 26101

Query: 1751  VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ----SKA 1806
               +  S R             +  V   D G Y+    N  G+     TL +Q    ++ 
Sbjct: 26102 QVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEK 26161

Query: 1807  SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQA---------PRFITQ---LNGPT 1854
             ++    + +S   +++  E     +R +  E +  +A         PR   Q   ++ P 
Sbjct: 26162 AVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPREKVQHLPVSAPP 26221

Query: 1855  KLSE-------GQSAHYECRIEPYPDPNMRVEWYFNGKVL-QSGH-RYRTSNDFGFAALD 1905
             K+++        + A   C +E        V WY +GK L ++GH ++  S D G   L 
Sbjct: 26222 KITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD-GTYELK 26280

Query: 1906  ILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYK 1965
             I  +   D GEY C+     G + ++++   Q+ +SI       S  +K      +S   
Sbjct: 26281 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 26340

Query: 1966  RAVQDDSF--VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023
             R  +  +   +  KP     +++  V+           T   +P     W  +G+ + QG
Sbjct: 26341 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT--GEPRPTAIWTKDGKAITQG 26398

Query: 2024  HRFKTTYDFGYVALDILYAYAEDTGTYM-------------CKAT-NAVG--EAVTTSSV 2067
              ++K + D G   L+I      D+G Y              CK T  A+   EA   S+ 
Sbjct: 26399 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 26458

Query: 2068  KVDA----KSGLYLDTLDEQRLK----KIQELEKYERPKPIEEEQPG--QRPVFLTALTS 2117
             K       K  +  + + ++ L+    K+ E +  E+    EE         V  +A TS
Sbjct: 26459 KTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATS 26518

Query: 2118  LENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE 2177
             LE     +      +       H  I  F     I  G R     +    A D+ +    
Sbjct: 26519 LEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG-ATDVKWVLNG 26577

Query: 2178  DSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEP 2237
                T   +    +  +  T T+K A HR+  + T      E I + +       + + + 
Sbjct: 26578 VELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYD-----LTLSKE 26632

Query: 2238  KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297
                 P F+++ R + ++ EG+   F C++    +P+  IE++ N   +  ++   I+   
Sbjct: 26633 LSDAPAFISQPR-SQNINEGQNVLFTCEISG--EPSPEIEWFKNNLPISISSNVSISRSR 26689

Query: 2298  GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
                SL+I++    D+G+Y++KA N  G C++  S+ V
Sbjct: 26690 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 76/284 (26%), Positives = 117/284 (41%), Gaps = 24/284 (8%)

Query: 1553 EQIQVLEDR-SKYHRTDMVD---EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDAT 1608
            E+ +VL  R +K   T  V    E+    P   + LKNV + EG+    E  +      T
Sbjct: 868  ERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT 927

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
              V WY  +  ++S   F  T   G   L I     EDSG +TC A+N  G   TS    
Sbjct: 928  --VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLA 985

Query: 1669 VHSKKSIYLES----------QHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVF-TMPM 1717
            V   +    E+          +      R   + DTS  +  +   E    AP F T P+
Sbjct: 986  VQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGE--PAAPYFITKPV 1043

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYVALNMKYV 1775
               ++ E  +  F  ++   G+PK  V W ++GVP+    R    ++   G   L +   
Sbjct: 1044 VQ-KLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMT 1100

Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
              +D+G YT    N+ GE   S++L  ++   L ++SQ E   Q
Sbjct: 1101 FADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQ 1144



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 71/267 (26%), Positives = 105/267 (39%), Gaps = 27/267 (10%)

Query: 4395 QTQERVVEGPVKPSK--------PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            +T E + E PV P+K         PIF K++    +   + A   V   G P P I+W+ 
Sbjct: 3433 ETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFF 3492

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
                +  S D++         LII    +ED   +  +A N  G   CSA L +  K   
Sbjct: 3493 NGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEG 3552

Query: 4507 GR---------------GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
             +               GG  PP F    + +    G     +  V G     V W K  
Sbjct: 3553 HKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKEN 3612

Query: 4552 KKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT-- 4608
            K++   +   I+   +G+ T ++ +   +DSG Y C A N  GE+ C AE +V L  T  
Sbjct: 3613 KQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDM 3672

Query: 4609 KDKPKPQTKAANAPPEIIE-PLKDKIV 4634
             D P        AP +  + PLK   V
Sbjct: 3673 TDTPCKAKSTPEAPEDFPQTPLKGPAV 3699



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 52/182 (28%), Positives = 81/182 (44%), Gaps = 2/182 (1%)

Query: 391   APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHA 449
             AP F +  ++ +V         C+VTG P P V W+   ++I  D   ++I   + G H 
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489

Query: 450   LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
             L+I +VT  D+ V    A N+ G  +    L V    ++  PK +E    ++   GE V 
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVS 24549

Query: 510   LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR-AKASDAAWYQCTAQNV 568
             +     G P P ITWQK    I  N   ++      ++L  P   +  DA +Y   A+N 
Sbjct: 24550 IKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNR 24609

Query: 569   AG 570
              G
Sbjct: 24610 FG 24611



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 70/280 (25%), Positives = 120/280 (42%), Gaps = 20/280 (7%)

Query: 922   KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
             +EGG   +  ++E    ST +V W    R +E S +    +  G   L +K +T  D G 
Sbjct: 25083 EEGGHVKYVCKIENYDQST-QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 25141

Query: 982   YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
             Y C+  N  G+ ++ A L +   +++              Y     +  KR  + +++ +
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVREVYD-----------YYCRRTMKKIKRRTDTMRLLE 25190

Query: 1042  K-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY---HD 1097
             + P F  PL      V G++  F   +    +  +T  WY +G++I   +  + Y    D
Sbjct: 25191 RPPEFTLPLYNKTAYV-GENVRFGVTITVHPEPHVT--WYKSGQKIKPGDNDKKYTFESD 25247

Query: 1098  FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
              G   L I SV  +D   YTVVARN  GE    A +TV T     T S  R ++++    
Sbjct: 25248 KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-TLHPPPTDSTLRPMFKRLLAN 25306

Query: 1158  EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHL 1197
              E +  + +     +S   P  ++   +  P+S G NI +
Sbjct: 25307 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEI 25346



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 87/390 (22%), Positives = 146/390 (37%), Gaps = 19/390 (4%)

Query: 489   VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
             +A + + +  ++ V EGE    +    G P P +TW + G  +  +   ++ T    ST 
Sbjct: 26062 LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF 26121

Query: 549   DIPRAKASDAAWYQCTAQNVAGS-----TATRARLYXXXXXXXXXXQKRLHLPR---PTK 600
             +I   +ASD   Y    +N  G      T T  +            + +   PR   P  
Sbjct: 26122 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 26181

Query: 601   VXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYP---PPQFIVPLKSVTAMEGGKIHFE 657
             V            + + V        P E+ +  P   PP+    LK+  + E  K+   
Sbjct: 26182 VKSPKRVKSPEPSHPKAVSPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKL--T 26239

Query: 658   TRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSA 716
               +E       ++ W K+G+ ++ +  F   +   G   L + +L   D GEY C     
Sbjct: 26240 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGE 26299

Query: 717   TGVAETKAVLHVTPRATI-ERTSQHPETLQYIQQLEDYSKYQHQE-SIEEQTSQRPQFIR 774
              G ++T          +I E+ S+  ET +  Q+  + +  +  E    E  S +P  + 
Sbjct: 26300 GGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVT 26359

Query: 775   PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMH 834
              LQD   +     A F  + T    PT    W KDG+ IT   +     + G   L I  
Sbjct: 26360 GLQDT-TVSSDSVAKFAVKATGEPRPT--AIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 26416

Query: 835   LRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
                 D+G YT    N  G   S+  + + A
Sbjct: 26417 TDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26446



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 64/231 (27%), Positives = 102/231 (44%), Gaps = 31/231 (13%)

Query: 255  EIDRS-LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE 313
            E D S L  +  P    KP + K  EGA+ +F +++ G P P   WF +GQ+++N   H+
Sbjct: 1399 ETDESQLERLYKPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHK 1458

Query: 314  IITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYIT 372
            ++   + T +L +     SDSG +T++A+N  G    S  L VE+  E  V+    + + 
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA-VEHQVKPMFVEKLK 1517

Query: 373  DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
            +   +E   R+E+  +A                          TG P P++ W  N   I
Sbjct: 1518 NVNIKE-GSRLEMKVRA--------------------------TGNPNPDIVWLKNSDII 1550

Query: 433  RDDYNHKILV-NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
                  KI +    G  AL I +    DS   T  A NK+G    +C++NV
Sbjct: 1551 VPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 3/183 (1%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            ++IE+S    AP+  +  Q + V +G    F  RV G+P PE  W+ N  +I        
Sbjct: 2021 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2080

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
               E     L+I +VT  DS  +   A N +GET+    L +++ +Q++   F +    +
Sbjct: 2081 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLIT--FTQELQDV 2137

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +E + +         P  ++ W KDG+ +    + R+H+D     L I     SDA  
Sbjct: 2138 VAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAED 2197

Query: 561  YQC 563
            Y C
Sbjct: 2198 YSC 2200



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 46/192 (23%), Positives = 84/192 (43%), Gaps = 3/192 (1%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P I + +KD     G+A + SC+IVG+PLP ++WY+  K +  S+ ++MS     +TL +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                  EDEG Y C+A N  G V  ++KL +    Q    P            G   +   
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFH--PGYPLKEKYYGAVGSTLRLHV 24153

Query: 4743  QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE-DTGTFTCRATTAAGQ 4801
                 +  P + W     L+  + +  + +  +   L++ N   +   G +  + +   G 
Sbjct: 24154 MYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 24213

Query: 4802  VETSAKLVVKSK 4813
             V+    + ++ K
Sbjct: 24214 VDAILDVEIQDK 24225



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 69/247 (27%), Positives = 97/247 (39%), Gaps = 11/247 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P     L N+  + EGE+   E  ++    P   V WY     +++   F+     G   
Sbjct: 897  PTLVSGLKNVTVI-EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIAR 953

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDK-IAAL 3538
            L I   + EDSG + C A N  G   T+  + VQ       E+        T +K     
Sbjct: 954  LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1013

Query: 3539 EGYSGTVDTLTPE-AESGNP--PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
                 T  +LT E A  G P  P F T P    L E  S  F C++    +    V W  
Sbjct: 1014 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKK 1071

Query: 3596 NGKPLLTGSRVKTI--NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G PL TG R K       G   L I   +  DAG YT    N+HGE + S  L  +   
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131

Query: 3654 GIILEPQ 3660
             ++++ Q
Sbjct: 1132 ELLMKSQ 1138



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 65/234 (27%), Positives = 100/234 (42%), Gaps = 16/234 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLS--GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            P   +K  + +L+    A F+ +L+   +P   V W  +G+ L  +N+  +I    + +L
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSL 1716

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG  T  A N  G   TS  L V+       + Q  +     Q+ E  ER+
Sbjct: 1717 DYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERM 1776

Query: 384  EISEKALA-----------PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
               E AL            P  V   +   V EG+  RF CRVTG P P+V W++N + I
Sbjct: 1777 -AHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLI 1835

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
            R   + +  V   G H L I +    D+G V   A N  G    + +L + ++E
Sbjct: 1836 RK--SKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1887



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 64/235 (27%), Positives = 103/235 (43%), Gaps = 28/235 (11%)

Query: 3839  HTVEESEG-VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
             H V E  G V++ C++E   D   ++ WY   + L +  +Y   Y+ G   L +  +   
Sbjct: 25079 HAVGEEGGHVKYVCKIE-NYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 25137

Query: 3898  DSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEV 3957
             D G Y C+ VND+GED + A +  K + + +      R MK+          IK+ T  +
Sbjct: 25138 DDGTYRCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKK----------IKRRTDTM 25186

Query: 3958  YLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG---K 4014
              L E         +PP F   + ++T+ V  E  +F   +    +P+  V W+ +G   K
Sbjct: 25187 RLLE---------RPPEFTLPLYNKTAYVG-ENVRFGVTITVHPEPH--VTWYKSGQKIK 25234

Query: 4015  PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
             P  +  ++T   D G   +    V  +D  EY   A N YG D  KA +  T  P
Sbjct: 25235 PGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP 25289



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 37/91 (40%), Positives = 51/91 (56%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP ++  LK+  V EG+++   C I G P PTV WY+ D  I+ S  FQ++  +    L 
Sbjct: 896  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            I EAF ED G + C A N AG V+ +  L V
Sbjct: 956  IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 83/384 (21%), Positives = 154/384 (40%), Gaps = 28/384 (7%)

Query: 2787  EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
             EG++  F C+ +    PT  + W    + L +  R++ T      + +I+     D G Y
Sbjct: 26077 EGESARFSCDTDGEPVPT--VTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 26134

Query: 2847  TCKATNSKGSATTSGSLRC----TGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPS 2902
             +    NS+G      +L        +K +    +    +  +++ E  +  +  K   PS
Sbjct: 26135 SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPS 26194

Query: 2903  VPDTEYP---KP---EWI--IPIAAEHQLVE-------GQVLHLEGQVEPKNDPDLKIEW 2947
              P    P   KP   E +  +P++A  ++ +        ++  L   VE       ++ W
Sbjct: 26195 HPKAVSPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTW 26254

Query: 2948  YFNGKVLEQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
             Y +GK L++   F+   S  G   L + ++ E D G Y C+   + G + T+      + 
Sbjct: 26255 YKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAF 26314

Query: 3007  DNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIA 3066
              ++ E+      T+  ++        RK   + P+  + +P    T  +D   +S   +A
Sbjct: 26315 KSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV-IVTGLQDTT-VSSDSVA 26372

Query: 3067  HYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRAT 3126
              +      TG+      W  +GK I    + +     G   LEI  T T+DSG Y+C   
Sbjct: 26373 KFAVKA--TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK 26430

Query: 3127  NKWGQAEISVKL--ECVDKSKGQK 3148
             N  G    S KL  + +  ++ QK
Sbjct: 26431 NSAGSVSSSCKLTIKAIKDTEAQK 26454



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 65/233 (27%), Positives = 94/233 (40%), Gaps = 15/233 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
            EG+    E  +   G PS    WY    +++    F+ T   G   L I    A D+G +
Sbjct: 910  EGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967

Query: 2582 MCKAINRAGXXXXX------XXXXXXXXXXIIDQAMRPESWEQIQLKEAAM--NKVPEMF 2633
             C A+N AG                      + +    E    ++ ++  M    + E  
Sbjct: 968  TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1027

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
               G   AP F T      KLVEG  V    QV     P+  + W K+GV LTTG R K 
Sbjct: 1028 AGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVGGNPKPH--VYWKKSGVPLTTGYRYKV 1084

Query: 2694 TFD--FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
            +++   G   L I+    DD+G YT    N  GE  ++AS+  E  + LL +S
Sbjct: 1085 SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1137



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 96/405 (23%), Positives = 167/405 (41%), Gaps = 51/405 (12%)

Query: 4409 KPPI-FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP+ FTK ++   V E   A  E E   E    +KW++    I  S  ++I        
Sbjct: 5785 EPPVEFTKPLEDQTVEEGATAVLECEVSRENAK-VKWFKNGTEILKSKKYEIVADGRVRK 5843

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP--SFTLTAQNVNV 4525
            L+I     ED   +   A++     K S NL            +VPP   F     ++ V
Sbjct: 5844 LVIHDCTPEDIKTYTCDAKD----FKTSCNL-----------NVVPPHVEFLRPLTDLQV 5888

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
               ++ R + +++  +   V W K+G +++   +  I+ +     L+I +    D  +Y 
Sbjct: 5889 REKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYS 5947

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C       E R  A     L   +++       AN     IE      V+E   I+  C+
Sbjct: 5948 C-------EVR-TARTSGMLTVLEEEAVFTKNLAN-----IE------VSETDTIKLVCE 5988

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             V KP   V WYKGD+ I  +  +++     +  L I  A  ED G+Y C   +S     
Sbjct: 5989 -VSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSS----R 6043

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
               K+KV +         ++  +++ + EG+ A+F   I+ +  P +QW R+   +    
Sbjct: 6044 TDGKVKVHEL----AAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGD 6098

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCR--ATTAAGQVETSAKL 4808
             + +I +G   VL++ +   +D GT+     A  AA  +    KL
Sbjct: 6099 KYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKL 6143



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 61/306 (19%), Positives = 128/306 (41%), Gaps = 17/306 (5%)

Query: 4308  KVTSNTVAKSMAQRYEDNLDQTEEVTEQR---VQKKVTQKPRIPDPSESTVHGKEVHVAK 4364
             K+T   +  + AQ+   +  +T E+T Q+   VQ++++QK    +  + +    +  +A 
Sbjct: 26441 KLTIKAIKDTEAQKV--STQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLAL 26498

Query: 4365  QKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFE 4424
             +++  K ++ ++      TS E + +  +     +  E     ++   F+ +M    + E
Sbjct: 26499 KEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMS---INE 26555

Query: 4425  HEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484
              ++   +    G     +KW      + NS +++     +   L I+Q    D  +   +
Sbjct: 26556 GQRLVLKANIAGATD--VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCI 26613

Query: 4485  AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
             ++ + G  KC  +L + ++          P+F    ++ N+  GQ V    +++G    +
Sbjct: 26614 SKTKEGIVKCQYDLTLSKELSDA------PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26667

Query: 4545  VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
             + W KN   +       I      Y+L I  A   DSGKY   A N  G+    A  +V 
Sbjct: 26668 IEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV- 26726

Query: 4605  LPATKD 4610
             LP  ++
Sbjct: 26727 LPLVEE 26732



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 56/215 (26%), Positives = 95/215 (44%), Gaps = 17/215 (7%)

Query: 3709  EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
             EGG V + C++E   D + ++ W+   R      +     + G   L +  I   D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 3769  TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
              C+  N +G  ++ A++     R+ V +    + M  +KIK     R +D  +   ++  
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTM--KKIK-----RRTDTMR---LLER 25191

Query: 3829  PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG---HRYRTVYDMG 3885
             PP+F   + + T    E VRF   +    +P   + WY++G+ +  G    +Y    D G
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 25249

Query: 3886  FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
                L I  V  +D  EY   A N +GED  KA ++
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLT 25284



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 80/338 (23%), Positives = 140/338 (41%), Gaps = 52/338 (15%)

Query: 1739  DPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
             D   +V W      +E S +    ++ G   L +K +   D GTY C+ +N+ GE  + +
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 1799  TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE 1858
              LFV+    +  +      ++KI++  D+ R   R          P F   L   T    
Sbjct: 25158 ELFVKGVREVY-DYYCRRTMKKIKRRTDTMRLLERP---------PEFTLPLYNKTAYV- 25206

Query: 1859  GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
             G++  +   I  +P+P+  V WY +G+ ++ G      ND  +        +  D G Y 
Sbjct: 25207 GENVRFGVTITVHPEPH--VTWYKSGQKIKPG-----DNDKKYT-------FESDKGLYQ 25252

Query: 1919  CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQ-----DDSF 1973
                       ++S+  +         D    + + + +Y ED  + K  V       DS 
Sbjct: 25253 L--------TINSVTTD---------DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDST 25295

Query: 1974  VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD-F 2032
             +  +P F + + NAE  EG  V  E  ++ +  PT++  W  +G+P+  G   +  ++  
Sbjct: 25296 L--RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGL 25351

Query: 2033  GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
              Y AL I     EDTG Y   ATN  G     + ++V+
Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 88/324 (27%), Positives = 125/324 (38%), Gaps = 61/324 (18%)

Query: 3077  DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ----A 3132
             DQS  + W++  + +E S +    Y  G+ +L +      D GTY C+  N +G+    A
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 3133  EISVK-------LECVDKSKGQK------------PRFTTHIQNIEGLKDGQSAHFECTV 3173
             E+ VK         C    K  K            P FT  + N      G++  F  T+
Sbjct: 25158 ELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYV-GENVRFGVTI 25216

Query: 3174  VPVDDPDMKIEWYHNGQPMRHSTRIKTV---SDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
                  P+  + WY +GQ ++     K     SD G   L I      D  EY   A NKY
Sbjct: 25217 TV--HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKY 25274

Query: 3231  GEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQD 3290
             GED      +C  K  V   +L P                   P T S   P F   + +
Sbjct: 25275 GED------SCKAKLTV---TLHP-------------------PPTDSTLRPMFKRLLAN 25306

Query: 3291  VTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD-FGIVILDILYCYE 3349
               +  EGQS  FE R+  +  P LK  W  +G+ L  G      H+      L I     
Sbjct: 25307 A-ECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLP 25363

Query: 3350  ENSGEYECVATNKLGRDSTKANLK 3373
             E++G Y   ATN  G  S +A+L+
Sbjct: 25364 EDTGYYRVTATNTAGSTSCQAHLQ 25387



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 68/248 (27%), Positives = 105/248 (42%), Gaps = 17/248 (6%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ +T  P  +  LK    ++EG+S   E  +      T+T  WY    QI S+   Q  
Sbjct: 891  EIPVTP-PTLVSGLKNVT-VIEGESVTLECHISGYPSPTVT--WYREDYQIESSIDFQIT 946

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID---TSSIHRGLYE 1152
               G   L I    AEDSG +T  A N AG    S  + V+     +   T+   +   E
Sbjct: 947  FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTE 1006

Query: 1153 KTRHIEESKFV--EPMYQIEEISKSKPVFVQPLSNP--PPVSEGKNIHLECRLEPMGDPT 1208
            + R +E    V  +     E+    +P     ++ P    + EG ++   C++   G+P 
Sbjct: 1007 EKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVG--GNPK 1064

Query: 1209 MRVEWFHNGRSVTVGSRFKTYYD--FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
              V W  +G  +T G R+K  Y+   G   L I    + D GEYT+   N  G   TSA 
Sbjct: 1065 PHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHG--ETSAS 1122

Query: 1267 VRVIERSD 1274
              ++E +D
Sbjct: 1123 ASLLEEAD 1130



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 92/390 (23%), Positives = 148/390 (37%), Gaps = 31/390 (7%)

Query: 3283  KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
             + +T+ + +T + EG+SA F        +P   V W   G+ L    R++          
Sbjct: 26065 RILTKPRSMT-VYEGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF 26121

Query: 3343  DILYCYEENSGEYECVATNKLGRDSTKANL---KCTSKENLILDSQLPRGMEGGLEKLQT 3399
             +I      + G Y  V  N  G+   +  L   K    E  +      +  E  ++  + 
Sbjct: 26122 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 26181

Query: 3400  LEDSMVRRKDTSVEEEKGKAPVFT----------VPLS---NIENLREGENAHFEARLTP 3446
             ++ S  R K       K  +P  T          +P+S    I    + E +   A+LT 
Sbjct: 26182 VK-SPKRVKSPEPSHPKAVSPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKLTC 26240

Query: 3447  TDDPNL----KVEWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNY 3501
               + ++    +V WY +GK LK    F+  +   G   L+I+     D GEY+C      
Sbjct: 26241 VVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEG 26300

Query: 3502  GEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIAALEGYSGTVDTLTPEAESGNPPEF 3560
             G + T      Q  ++I    ++ K  E    D+       +   +   PE  S  P   
Sbjct: 26301 GTSKTNLQFMGQAFKSI--HEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV-I 26357

Query: 3561  TTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIG 3620
              T   D  +S +S A F  +     +      W  +GK +  G + K   D G   LEI 
Sbjct: 26358 VTGLQDTTVSSDSVAKFAVKA--TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIH 26415

Query: 3621  GVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
                  D+GLYTC   N  G  + SCKL +K
Sbjct: 26416 KTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26445



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 85/377 (22%), Positives = 144/377 (38%), Gaps = 35/377 (9%)

Query: 2388  IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
             + EG++A F C     G+P   V W R  +++  S+R   T      +  IS V+  DEG
Sbjct: 26075 VYEGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEG 26132

Query: 2448  VYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ-KLEQPHE----RRSEEPD 2502
              Y     N  G+               +     P  +K  + +++ P      +R + P+
Sbjct: 26133 NYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPE 26192

Query: 2503  REFEKPIFTQVLTGPSELWEGQH----------------AHYE-ARVVPVGDPSL----R 2541
                 K + +   T P+   + QH                A  E A++  V + S+     
Sbjct: 26193 PSHPKAV-SPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKE 26251

Query: 2542  FEWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXX 2600
               WY +G +LK    F+  +   G   L IN++  +D G Y+C+     G          
Sbjct: 26252 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 26311

Query: 2601  XXXXXIIDQAMRPESWEQIQLK--EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQ 2658
                  I ++  +    ++   K  E+ + +  E      +   P+  T L+  D  V   
Sbjct: 26312 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQ--DTTVSSD 26369

Query: 2659  HVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCK 2718
              V   A V+   +P     W K+G  +T G + K + D G   L I+     DSG+YTC 
Sbjct: 26370 SVAKFA-VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCT 26428

Query: 2719  ATNLLGEAVSTASIKIE 2735
               N  G   S+  + I+
Sbjct: 26429 VKNSAGSVSSSCKLTIK 26445



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 79/340 (23%), Positives = 144/340 (42%), Gaps = 27/340 (7%)

Query: 2041 YAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPI 2100
            + +A+   TY  +A   V + V  S      +   + + L   R  K+ E  +   P P+
Sbjct: 835  FPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERF-EVL-HGREAKVTETARV--PAPV 890

Query: 2101 EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT 2160
            E   P   P  ++ L ++  + EG+    EC +     P  T+ W+    +I +   ++ 
Sbjct: 891  EI--PVTPPTLVSGLKNVTVI-EGESVTLECHISGYPSP--TVTWYREDYQIESSIDFQI 945

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT---QHPNGL 2217
            T   G   L I   +AEDSG + C A N+ G    +C L V        +T         
Sbjct: 946  TFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTT 1005

Query: 2218 EKIRQLEAQG-HSTRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQVEPVHD 2271
            E+ R +E++    T   + E +  P     P F+T+      + EG +  F CQV    +
Sbjct: 1006 EEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GN 1062

Query: 2272 PNLRIEFYHNGKALQSAARFHITFD--FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSA 2329
            P   + +  +G  L +  R+ ++++   G   L I     +DAGEY++   N  G  +++
Sbjct: 1063 PKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1122

Query: 2330 ISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPE 2369
             S+   A   ++ +SQ+    E + + +     + PE+ E
Sbjct: 1123 ASLLEEADYELLMKSQQ----EMLYQTQVTAFVQEPEVGE 1158



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 46/174 (26%), Positives = 87/174 (50%), Gaps = 9/174 (5%)

Query: 235   SFRESITKRYVGESDVQISTE--IDRSLGPVSPPKIAQKP------RNSKLQEGADAQFQ 286
             S  E ++K    +   Q +TE  + R   P +P  I+ KP      +++ +   + A+F 
Sbjct: 26316 SIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFA 26375

Query: 287   VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC 346
             V+ +G PRP   W K+G+ +    K+++        L +  T  SDSG YT   +N  G 
Sbjct: 26376 VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGS 26435

Query: 347   IVTSGYLAVESPTESYVQDQRSQYITD-TQQRETEERIEISEKALAPQFVKVCQ 399
             + +S  L +++  ++  Q   +Q  ++ T Q++   + EIS+KAL  + +K+ +
Sbjct: 26436 VSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSE 26489



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 7/195 (3%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  V+ +++ T ++E E+   EC ++  G P+  V W+     +     F   +  G  
Sbjct: 896  PPTLVSGLKNVT-VIEGESVTLECHIS--GYPSPTVTWYREDYQIESSIDFQITFQSGIA 952

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
             +     + EDSG + C A N  G   T   +          ++       + E+ R +E
Sbjct: 953  RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVE 1012

Query: 4092 ASWQVTPEQVVEESKAR----CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
            +   V  +  + E +A       P F++ P    + EG    F C+V G+PKP V W  +
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072

Query: 4148 GNTIVNGSRYKLTYD 4162
            G  +  G RYK++Y+
Sbjct: 1073 GVPLTTGYRYKVSYN 1087



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 57/205 (27%), Positives = 88/205 (42%), Gaps = 20/205 (9%)

Query: 3311  DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
             D   +V W++  ++L +  +Y   ++ G+ IL +    + + G Y C   N  G DS+ A
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 3371  NLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIE 3430
              L        + D    R M+            + RR DT    E+   P FT+PL N +
Sbjct: 25158 ELFVKGVRE-VYDYYCRRTMK-----------KIKRRTDTMRLLER--PPEFTLPLYN-K 25202

Query: 3431  NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC---DFGFVILEISPTYP 3487
                 GEN  F   +T   +P+  V WY +G+ +K G   + +    D G   L I+    
Sbjct: 25203 TAYVGENVRFGVTITVHPEPH--VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTT 25260

Query: 3488  EDSGEYLCRAYNNYGEAVTTASMKV 3512
             +D  EY   A N YGE    A + V
Sbjct: 25261 DDDAEYTVVARNKYGEDSCKAKLTV 25285



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 77/331 (23%), Positives = 137/331 (41%), Gaps = 23/331 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I   P   ++ EG  A+F+ +++G P+P+V W+ NGQ +  S +  +     H  L +
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHY-LDI 1853

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-----SYVQDQRSQYITDTQ---QR 377
             + +  D+G   + AENP G I     L ++   +         + R ++        Q 
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQF 1913

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKM--------TRFDCRVTGRPYPEVTWFIND 429
            E ++     +     + VK+ +   +T  K+        ++F  R T   Y E    +  
Sbjct: 1914 EVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR-TEEGYYEAITAVEL 1972

Query: 430  RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQV 488
            +  + D +++ L+ ++ +  L  T   L++          K     F  + + IE    +
Sbjct: 1973 KSRKKDESYEELLRKTKDELLHWTK-ELTEEEKKALAEEGKITIPTF--KPDKIELSPSM 2029

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH-TDGGAST 547
             APK  ER  +  V +G       R VG P P   W K+GV I  +  +  +  +     
Sbjct: 2030 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2089

Query: 548  LDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            L I    A D+A     A N+AG T++ A L
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFL 2120



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 74/321 (23%), Positives = 125/321 (38%), Gaps = 27/321 (8%)

Query: 240  ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
            + +   G S + +   ++     V P    +K +N  ++EG+  + +V+ +GNP P + W
Sbjct: 1485 VAQNRAGRSSISVILTVEAVEHQVKP-MFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1543

Query: 300  FKNGQRLINSN--KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE- 356
             KN   ++     K  I  T     L++ +T   DS  YT  A N  G   T   + VE 
Sbjct: 1544 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603

Query: 357  ------------SPTESY------VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
                         P  +Y        +    ++   Q++  E  +   EK   P F K  
Sbjct: 1604 EFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKL 1663

Query: 399  QDRDVTEGKMTRFDCRVT--GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
                +       F+CR+T    P   V W ++D +  +  N   ++NE G  +L      
Sbjct: 1664 TSLRLKRFGPAHFECRLTPISDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLDYGVAY 1722

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE--RFSTLNVREGEPVVLNARA 514
              DSG++TC A NK G       L V +++ +V    +   R     + E E +      
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGAL 1782

Query: 515  VGTPTPRITWQKDGVPIIPNP 535
             G  T +   QK  + + P P
Sbjct: 1783 TGVTTDQKEKQKPDIVLYPEP 1803



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 117/538 (21%), Positives = 220/538 (40%), Gaps = 83/538 (15%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            PQ ++ LQ +  +Q G+ A F A ++    P  ++ WYK+ + ++   +   + +    +
Sbjct: 3193 PQVLQELQPV-TVQSGKPARFCAMIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3249

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L ++    EDA  YT  A N  G  ++T S   A+ S    ++  P+Q   +        
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYG--VATTS---ASLSVEVPEVVSPDQEMPV-------- 3296

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                               P   TP++D ++  EG  A F+ R   +  + L+V W    
Sbjct: 3297 -----------------YPPAIITPLQDTVT-SEGQPARFQCR---VSGTDLKVSWYSKD 3335

Query: 950  RPVEASS--RITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
            + ++ S   R+T F +     L I      D G YT  A NA+GQ +++ANL++   + I
Sbjct: 3336 KKIKPSRFFRMTQFEDT--YQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESI 3393

Query: 1008 IAES-QHPGGLEKIQY-----------LEDAS-RYSKRTEEEVKITQKP----RFLGPLK 1050
            + E  +    +E  ++           L  A  + SK  E    +++ P    +F    +
Sbjct: 3394 LHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKE 3453

Query: 1051 GTNKIVEGQSAHFEARVEPQSDLTMTV--------EWYFNGKQITSANRIQTYHDFGYVA 1102
            GT  I   + ++ +  +   + L++TV        +W+FNG  +T +   +   D    +
Sbjct: 3454 GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHS 3513

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I   + ED G YT +A N  G+   SA + + ++          G  +       +K 
Sbjct: 3514 LIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG--------EGHKDTETESAVAKS 3565

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +E +          P F++ L    P+   + +        +G+P   V WF   + +  
Sbjct: 3566 LEKLG-----GPCPPHFLKELK---PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCT 3617

Query: 1223 GSRFKTYYDFGFVALDIIH-ATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDT 1279
               +   ++       I++     D+G Y  +A N LG +  +A + V+     +TDT
Sbjct: 3618 SVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 3675



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 62/243 (25%), Positives = 103/243 (42%), Gaps = 25/243 (10%)

Query: 4481  FAAVAENRGGTAKCSANLV-VEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG 4539
             F   AEN  G ++     + ++ K   G      P      ++V    G+  +L  ++ G
Sbjct: 24006 FRVFAENETGLSRPRRTAMSIKTKLTSGEA----PGIRKEMKDVTTKLGEAAQLSCQIVG 24061

Query: 4540  TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                 D+ W + GK++    + K+  +  T+TL ++    +D G Y C+A N  GE    +
Sbjct: 24062 RPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSS 24121

Query: 4600  ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV-AEGQAIEFSCKIVGKPLPTVQWYK 4658
             + +  L AT     PQ            PLK+K   A G  +      +G+P+P + W+ 
Sbjct: 24122 KLL--LQAT-----PQFHPG-------YPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFH 24167

Query: 4659  GDKLIKPSKYFQMSRTADEYTLRISEAFPE--DEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             G KL++ S+   +  T + YT  + +        G YK    N  G  TV A L V   D
Sbjct: 24168 GQKLLQNSENITIENT-EHYTHLVMKNVQRKTHAGKYKVQLSNVFG--TVDAILDVEIQD 24224

Query: 4717  QAD 4719
             + D
Sbjct: 24225 KPD 24227



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/313 (24%), Positives = 127/313 (40%), Gaps = 39/313 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P  F + ++   V E + A F  +   E    +KWYR    IK    ++     +   LI
Sbjct: 6325 PTEFVEHLEDQTVTEFDDAVFSCQLSREKAN-VKWYRNGREIKEGKKYKFEKDGSIHRLI 6383

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   ++D   +A   E+R    K  A L VEE         +P       Q++    G 
Sbjct: 6384 IKDCRLDDECEYACGVEDR----KSRARLFVEE---------IPVEIIRPPQDILEAPGA 6430

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V    ++   K ++V WL+N   V    +++++ E   + L I +  P+D G+Y  +A 
Sbjct: 6431 DVVFLAELNKDK-VEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAK 6489

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            +   EAR   E   +         P+ K A+         +D +V  G+ +         
Sbjct: 6490 DK--EARAKLELAAA---------PKIKTAD---------QDLVVDVGKPLTMVVPYDAY 6529

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P    +W+K +   +P     +  TA++ + RI EA   D+G YK V  N  G+      
Sbjct: 6530 PKAEAEWFKEN---EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFIN 6586

Query: 4710 LKVTQ-PDQADNL 4721
            LKV   P    NL
Sbjct: 6587 LKVIDVPGPVRNL 6599



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 59/243 (24%), Positives = 98/243 (40%), Gaps = 9/243 (3%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +S L N+   EG+++  EC++     PT  + W+  +  + S   ++ T       L I 
Sbjct: 900  VSGLKNVTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIR 957

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEA---VEQAEEA 2893
              + EDSG +TC A N  G+ +TS  L     +    +T     K   E    VE  +  
Sbjct: 958  EAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVV 1017

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
                           P   + I      +LVEG  +    QV    +P   + W  +G  
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVP 1075

Query: 2954 LEQGSRFKLT--SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011
            L  G R+K++     G   L +   +  D+G YT    NK GE   S+++   +   L+ 
Sbjct: 1076 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1135

Query: 3012 RTQ 3014
            ++Q
Sbjct: 1136 KSQ 1138



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 48/175 (27%), Positives = 72/175 (41%), Gaps = 7/175 (4%)

Query: 405  EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVV 463
            EG +      +T     EV W+  ++ +  D   K L +++  + L+I  V   D  G  
Sbjct: 4256 EGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEY 4312

Query: 464  TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
             C A N SG+TA   +L V+++    AP    +   L V  G            P  R  
Sbjct: 4313 VCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQ 4369

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            W K G  I  + +  I +    S+L+I R +  D   Y C A N  GS +  A L
Sbjct: 4370 WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 4424



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 6/136 (4%)

Query: 232   REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
             R+      I+K   G    Q    + + L     P    +PR+  + EG +  F  ++SG
Sbjct: 26605 RDEGILTCISKTKEGIVKCQYDLTLSKELSDA--PAFISQPRSQNINEGQNVLFTCEISG 26662

Query: 292   NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG-CIVTS 350
              P P + WFKN   +  S+   I  + N  +L +RN   SDSG YT+ A+N  G C  T+
Sbjct: 26663 EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 26722

Query: 351   GYLA---VESPTESYV 363
               +    VE P+   V
Sbjct: 26723 SLMVLPLVEEPSREVV 26738



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 94/396 (23%), Positives = 156/396 (39%), Gaps = 52/396 (13%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            ++   V E  +A  E +     +  +KWY  +  IK     Q     TK  L+I +    
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D   +  +     G  + + NL VE K +  RG           +++  T  Q V  + +
Sbjct: 2465 DEGPYKLIV----GRVETNCNLSVE-KIKIIRG----------LRDLTCTETQNVVFEVE 2509

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            ++ +  IDV W    K+++P  + KI      Y L +L     D GKY       AGE  
Sbjct: 2510 LSHSG-IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFY----AGENM 2564

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               +  V                 A   I +PL D+ VAE Q   F C+ V  P    +W
Sbjct: 2565 TSGKLTV-----------------AGGAISKPLTDQTVAESQEAVFECE-VANPDSKGEW 2606

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  K +  +   +      +  L I+    +D G+Y    Y  A   T +AKLKV    
Sbjct: 2607 LRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY---TYKVATSKT-SAKLKV---- 2658

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
              + +     L+++ V E Q A F  ++T      +QW++ G ++     + +  +G   
Sbjct: 2659 --EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIY 2716

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             L I N    D   +  R     G++  SA+L V++
Sbjct: 2717 SLRIKNCAIVDESVYGFR----LGRLGASARLHVET 2748



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 55/218 (25%), Positives = 95/218 (43%), Gaps = 18/218 (8%)

Query: 3162  KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
             ++G    + C +   D    ++ WY   + + +S + +   + G  +L +      D G 
Sbjct: 25083 EEGGHVKYVCKIENYDQ-STQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 25141

Query: 3222  YVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE- 3280
             Y C+  N YGED + A +   G   VY      D   +     +++  +++T +    E 
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVREVY------DYYCR----RTMKKIKRRTDTMRLLER 25191

Query: 3281  PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG---HRYRTFHDF 3337
             PP+F   + + T  V G++  F   +     P+  V W+ +G+K+  G    +Y    D 
Sbjct: 25192 PPEFTLPLYNKTAYV-GENVRFGVTITV--HPEPHVTWYKSGQKIKPGDNDKKYTFESDK 25248

Query: 3338  GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
             G+  L I     ++  EY  VA NK G DS KA L  T
Sbjct: 25249 GLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 25286



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 87/400 (21%), Positives = 165/400 (41%), Gaps = 50/400 (12%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            K +    VF  E A FE+E   EP    +W  +  P+  SPD +I     K ILI+    
Sbjct: 5258 KPLYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQ 5316

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            +  +   +  A N    AK +ANL V+E         +P  F     +V V      + +
Sbjct: 5317 LGMTGEVSFQAAN----AKSAANLKVKE---------LPLIFITPLSDVKVFEKDEAKFE 5363

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +V+  +P    WLK  +++  D R +++++   ++++I  A  +D  KY    +  A +
Sbjct: 5364 CEVS-REPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKY----MFEAED 5418

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
                 + ++     K                + PLKD    E ++  F+ ++    +  V
Sbjct: 5419 KHTSGKLIIEGIRLK---------------FLTPLKDVTAKEKESAVFTVELSHDNI-RV 5462

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W+K D+ +  ++   M      +++   +   +D    +  A   +      AKL V +
Sbjct: 5463 KWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSE----AKLTVLE 5518

Query: 4715 PDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
             D     P  T  L+D    E      + +I SK    ++W ++G  I  + +  +  +G
Sbjct: 5519 GD-----PYFTGKLQDYTGVEKDEVILQCEI-SKADAPVKWFKDGKEIKPSKNAVIKTDG 5572

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               +L++    + D G +TC      G  +TS KL ++ +
Sbjct: 5573 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 5608



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 81/337 (24%), Positives = 134/337 (39%), Gaps = 43/337 (12%)

Query: 1324  EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
             EG +V   C+++   DQ+ +V W+   + ++   ++   YE     L +  +   D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 1384  TCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIK 1443
              C+  N  GE  +   L V   ++ + +      ++KI+   DT R  +          +
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKRRTDTMRLLE----------R 25191

Query: 1444  PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
             P   T P   +    G++V F   +    + +  V W+K+GQ +  G      +D  Y  
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPH--VTWYKSGQKIKPGD-----NDKKYT- 25243

Query: 1504  LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
                      D G+Y    +N V TD+ +        T + R+   E   +    +     
Sbjct: 25244 ------FESDKGLYQL-TINSVTTDDDA------EYTVVARNKYGEDSCKAKLTVTLHPP 25290

Query: 1564  YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
                TD     +T  P+    L N E +EGQ   FE R+  +   TLK  W  + +PL  G
Sbjct: 25291 --PTD-----STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLG 25341

Query: 1624  SRFTETN-NFGFVALDIMSCLPEDSGTYTCRAINALG 1659
                   +    + AL I   LPED+G Y   A N  G
Sbjct: 25342 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 25378



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 53/200 (26%), Positives = 87/200 (43%), Gaps = 16/200 (8%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            D    Y  + + ++T  R+ ++   L  +F+   +D+ V EG+   F C ++      V 
Sbjct: 5052 DDEGVYTAEVEGKKTSARLFVTGIRL--KFMSPLEDQTVKEGETATFVCELSHEKM-HVV 5108

Query: 425  WFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            WF ND ++    +  +L++  G  H L +  VTL D   +    +  S  TA   +L V+
Sbjct: 5109 WFKNDAKLHT--SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSS-TA---QLKVL 5162

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            E +    P F  +       E + + L    V    P + W KDG  I+P+P+  I  DG
Sbjct: 5163 EAD----PYFTVKLHDKTAVEKDEITLKCE-VSKDVP-VKWFKDGEEIVPSPKYSIKADG 5216

Query: 544  GASTLDIPRAKASDAAWYQC 563
                L I +A   D   Y C
Sbjct: 5217 LRRILKIKKADLKDKGEYVC 5236



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 53/203 (26%), Positives = 92/203 (45%), Gaps = 10/203 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVY 3101
            T + P FT   + +V + EG  A +EA +  +G     + WF +G+ I  S    ++  +
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
            + G   L I      +SG YS +ATN  GQA  + +L  + K++   P F   +Q++  +
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMT-V 115

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            + G     +  V  + +P +K  +Y +G  ++ S   +   +     L IA     DSG 
Sbjct: 116  RQGSQVRLQVRVTGIPNPVVK--FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGT 173

Query: 3222 YVCRAYNKYGEDFTRATINCYGK 3244
            Y   A N  G   + A +   G+
Sbjct: 174  YSVNATNSVGRATSTAELLVQGE 196



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 60/237 (25%), Positives = 91/237 (38%), Gaps = 16/237 (6%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
            EG +   E  ++    PT  V WY++   I +S      F  G   L I    AED+G +
Sbjct: 910  EGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967

Query: 844  TVRAVNKLGEAISTASIRVAA------RSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXX 897
            T  AVN+ G   ++  + V         +T   +    E++R++E               
Sbjct: 968  TCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQ 1027

Query: 898  XXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR 957
                 P     P F T    Q  + EGG   F  ++   G+    V W K G P+    R
Sbjct: 1028 AG---PGEPAAPYFITKPVVQ-KLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYR 1081

Query: 958  ITTFFN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
                +N   G   L I      DAG YT    N  G+ + SA+L      +++ +SQ
Sbjct: 1082 YKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1138



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 62/244 (25%), Positives = 102/244 (41%), Gaps = 15/244 (6%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            +++ EG     E  +      T  V W ++   +E+S      F  G   L I+     D
Sbjct: 906  VTVIEGESVTLECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAED 963

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ---HPGGLEKIQYLEDASRY---SKR 1032
            +G +TC A N  G  +TS  L +   ++   E+         E+ +++E        +  
Sbjct: 964  SGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSL 1023

Query: 1033 TEEEVKITQK--PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN 1090
            TEE+    +   P F+       K+VEG S  F  +V    +    V W  +G  +T+  
Sbjct: 1024 TEEQAGPGEPAAPYFITK-PVVQKLVEGGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGY 1080

Query: 1091 RIQTYHD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
            R +  ++   G   L I+   A+D+G YT+V RN  GE   SAS+  E    +   S   
Sbjct: 1081 RYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQE 1140

Query: 1149 GLYE 1152
             LY+
Sbjct: 1141 MLYQ 1144



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 111/491 (22%), Positives = 179/491 (36%), Gaps = 38/491 (7%)

Query: 3182  KIEWYHNGQPMRHSTRIKT-VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             ++ WY +G+ ++ +   +   S  G   L I      D GEYVC    + G   T     
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26310

Query: 3241  CYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP----PKFITQIQDVTKLVE 3296
                   ++ E +   S  K  + ++ +    +     + EP    P  +T +QD T +  
Sbjct: 26311 GQAFKSIH-EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSS 26368

Query: 3297  GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDI---------LY- 3346
                A F  +     +P     W  +GK +  G +Y+   D G   L+I         LY 
Sbjct: 26369 DSVAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYT 26426

Query: 3347  CYEENSG---EYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK-LQTLED 3402
             C  +NS       C  T K  +D T+A    T K + I   +     E   +K L++ E 
Sbjct: 26427 CTVKNSAGSVSSSCKLTIKAIKD-TEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26485

Query: 3403  SMVRRKDT---SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWN 3459
              M   K     +++EE  K  +      +     E    H E  +T T   + +V  +  
Sbjct: 26486 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEE--ITKTSQASEEVRTH-- 26541

Query: 3460  GKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNII 3519
                +KA S   +  +   ++L+ +     D    L        E        V G    +
Sbjct: 26542 -AEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYG---VSGSDQTL 26597

Query: 3520  LESQLPKGMEGTIDKIAAL-EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFE 3578
                Q     EG +  I+   EG       LT   E  + P F + P    ++E  +  F 
Sbjct: 26598 TIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFT 26657

Query: 3579  CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
             C +    + S  +EWF N  P+   S V          LEI      D+G YT KA N  
Sbjct: 26658 CEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFR 26715

Query: 3639  GEATVSCKLQV 3649
             G+ + +  L V
Sbjct: 26716 GQCSATASLMV 26726



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 35/116 (30%), Positives = 55/116 (47%)

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            V +    +VT  A++             ++ L+++ V EG+    +  I+    PT+ W 
Sbjct: 872  VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 931

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            RE   I  + DFQ+  +   A L+I   + ED+G FTC A   AG V TS  L V+
Sbjct: 932  REDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 165/768 (21%), Positives = 292/768 (38%), Gaps = 65/768 (8%)

Query: 3675 LEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
            LEE   ++  + I + +     F + IK N  + EG  V F C++   G P  +I W+ +
Sbjct: 1225 LEEDGEEKMAVDISESEAVESGFDLRIK-NYRILEGMGVTFHCKMS--GYPLPKIAWYKD 1281

Query: 3735 GRPFATGSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
            G+    G R     L D G  +L I  +   D G YT  A+N  G+A  + K+       
Sbjct: 1282 GKRIKHGERYQMDFLQD-GRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAP 1340

Query: 3793 IVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECR 3852
            +   + +P      +I+ L    +S +P         P  ++  +      S G R E  
Sbjct: 1341 LGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEET 1400

Query: 3853 VEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
             E + +   +  +                +D+  V   +   +    G+ I   VND+  
Sbjct: 1401 DESQLERLYKPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQI---VNDYTH 1457

Query: 3913 DFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQP 3972
               K  I       +I+    P        + Q  A   + +  V LT +    V+ +  
Sbjct: 1458 ---KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRA--GRSSISVILTVE---AVEHQVK 1509

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLL-HKNRFTPIYDF-GY 4030
            P FV ++++       E ++ E ++   G+PN  + W  N   ++ HK     I    G 
Sbjct: 1510 PMFVEKLKNVNI---KEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGE 1566

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT---GKPGIVYDSQLPKHMKSIEKI 4087
             A+       +DS  Y   A N  G D T+  +       +P       +P+     ++I
Sbjct: 1567 AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEI 1626

Query: 4088 R--EME-ASWQVTPEQVVE----ESKARCPPVFVSLPDAVTVEEGEWARFCCRVT--GHP 4138
               E+E    +   EQ  E    + + +  P F     ++ ++    A F CR+T    P
Sbjct: 1627 AAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPISDP 1686

Query: 4139 KPRVMWLLNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXL 4197
               V WL +G  +   +R ++  + G    D       D+G I                L
Sbjct: 1687 TMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1746

Query: 4198 KVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGV-IDHRPELKPK 4256
             V     D + +++ +  P  +     QR E ELE+   E  +    GV  D + + KP 
Sbjct: 1747 IV----KDEKSLVEESQLP--EGRKGLQRIE-ELERMAHEGAL---TGVTTDQKEKQKPD 1796

Query: 4257 VIKEPE----TEWQQSVKRKKNEEY-YNKLQELENEQVIKES---RLR-ESTHQYAIPGD 4307
            ++  PE     E + +  R +   Y   K+    N Q+I++S   R+R +  H   I   
Sbjct: 1797 IVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDC 1856

Query: 4308 KVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQ 4367
            K       K  A+  E  ++   ++  Q+ +   +   R P+P        E HV +  +
Sbjct: 1857 KSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPR------PEFHVHEPGK 1910

Query: 4368 TQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK 4415
             Q EV   +++ R + +TET E+  K +  ER+    V      + +K
Sbjct: 1911 LQFEV---QKVDRPVDTTETKEVV-KLKRAERITHEKVPEESEELRSK 1954



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 55/229 (24%), Positives = 92/229 (40%), Gaps = 16/229 (6%)

Query: 2122  KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
             +EG    + C++E   D    + W+   +++    +Y  T++ G   L +      D GT
Sbjct: 25083 EEGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 25141

Query: 2182  YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISP 2241
             Y CK  N  GE  +   L V G R  + D      ++KI++        R +       P
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKR--------RTDTMRLLERP 25192

Query: 2242  PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ---SAARFHITFDFG 2298
             P F   L   T  + G+   F   +  VH P   + +Y +G+ ++   +  ++    D G
Sbjct: 25193 PEFTLPLYNKT-AYVGENVRFGVTI-TVH-PEPHVTWYKSGQKIKPGDNDKKYTFESDKG 25249

Query: 2299  YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
                L I     +D  EY+V A N  G  +    +TVT        + RP
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 25298



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 83/405 (20%), Positives = 152/405 (37%), Gaps = 68/405 (16%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+ + +++  TV+  +  RF   +  +  PK  I WY+  +LL +G + +         
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAMISGRPQPK--ISWYKEEQLLSTGFKCK--------- 3240

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
                  +  D  EY    +  F ED   A  +C+   D         G+  + A   +E 
Sbjct: 3241 ------FLHDGQEYTLLLIEAFPED--AAVYTCEAKNDY--------GVATTSASLSVEV 3284

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
                   EV   + ++       PP  +T +Q  T   E +  +F+C+   V   ++KV 
Sbjct: 3285 P------EVVSPDQEM----PVYPPAIITPLQD-TVTSEGQPARFQCR---VSGTDLKVS 3330

Query: 4009 WFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W+   K +   +RF  +  F     +     YPED G Y   A N  G   + A +    
Sbjct: 3331 WYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEA 3389

Query: 4068 KPGIVYD---SQLPKHMKSIE----------------KIREMEASWQVTPEQVV-----E 4103
               I+++    ++   MK                   ++ ++  + ++  E  V     +
Sbjct: 3390 PESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFD 3449

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
              K    P+F+       +  G+ A     V G PKP++ W  NG  +   + YK  +DG
Sbjct: 3450 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3509

Query: 4164 MYH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR 4207
              H   I  T+  D G+   +             LK+  + + ++
Sbjct: 3510 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK 3554



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 79/290 (27%), Positives = 112/290 (38%), Gaps = 26/290 (8%)

Query: 4481  FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG- 4539
             F    EN GG ++ S   + E    +    I  P F    +N+NV       L  KVTG 
Sbjct: 24400 FRVKCENLGGESEWSE--ISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGH 24457

Query: 4540  TKPIDVYWLKNGKKVQPD-IRNKILEEDGTYTLLILEAYPQDSGK-YECVAINSAGEARC 4597
              KPI V W + GK++  D ++ +I E  G Y  LI+ +   D    Y+  A N  G    
Sbjct: 24458 PKPI-VKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSG 24516

Query: 4598  DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
              A   V +PA    PK            +E +       G+ +       GKP P + W 
Sbjct: 24517 TASLEVEVPAKIHLPK-----------TLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ 24565

Query: 4658  KGDKLIKPSKYFQMSRTADEYTLRISEAFP-EDEGDYKCVAYNSAGRVTVAAKLKVTQ-P 4715
             KG  LI  + ++Q+  T    +L        +D G Y   A N  G      +L V   P
Sbjct: 24566 KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVP 24625

Query: 4716  DQADNLPALTPLRDIV-VYEGQPA-----QFKTQITSKIKPTIQ-WLREG 4758
             D    +      RD V +   +PA     +    I  K   T + WLR G
Sbjct: 24626 DPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG 24675



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 81/358 (22%), Positives = 141/358 (39%), Gaps = 54/358 (15%)

Query: 3571  ENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLY 3630
             E     + C+ I   D S +V W+   + L    + +   + G  IL +  + + D G Y
Sbjct: 25084 EGGHVKYVCK-IENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 3631  TCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDE 3690
              CK  N +GE +   +L VKG + +        + +   + I++  +T+   E       
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVY-----DYYCRRTMKKIKRRTDTMRLLER------ 25191

Query: 3691  KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTL- 3747
                PP FT+ +  N     G  V F   +    +P   + W+ +G+    G   + +T  
Sbjct: 25192 ---PPEFTLPLY-NKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFE 25245

Query: 3748  NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEK 3807
             +D G   L I+ +   D  EYT  A NK+G  +      C AK  + L            
Sbjct: 25246 SDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS------CKAKLTVTLHPP--------- 25290

Query: 3808  IKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR 3867
                         P +  +    P F   + +   +E + V FE RV     P L+  W +
Sbjct: 25291 ------------PTDSTL---RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEK 25333

Query: 3868  NGKLLPSGHRYRTVYD-MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
             +G+ L  G     +++ + + +L I     ED+G Y   A N  G    +A +  ++L
Sbjct: 25334 DGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERL 25391



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 78/342 (22%), Positives = 121/342 (35%), Gaps = 19/342 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN-K 470
            + RV   P P   +   D    D Y  +  V       + IT  T+ +        R  K
Sbjct: 822  ETRVRAEPTPLPQFPFADTP--DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAK 879

Query: 471  SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530
              ETA   R+    +  V  P  V     + V EGE V L     G P+P +TW ++   
Sbjct: 880  VTETA---RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQ 936

Query: 531  IIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQ 590
            I  + + +I    G + L I  A A D+  + C+A N AG+ +T   L           +
Sbjct: 937  IESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL---AVQVSEEFE 993

Query: 591  KRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAME 650
            K                       +           PGE       P FI        +E
Sbjct: 994  KETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEP----AAPYFITKPVVQKLVE 1049

Query: 651  GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--RFGYISLDMLSLNIQDSGE 708
            GG + F  ++   G+P   + W K+G  +    R+   +  + G   L +      D+GE
Sbjct: 1050 GGSVVFGCQVG--GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1107

Query: 709  YTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQL 750
            YT    +  G  ET A   +   A  E   +  + + Y  Q+
Sbjct: 1108 YTIVVRNKHG--ETSASASLLEEADYELLMKSQQEMLYQTQV 1147



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 92/397 (23%), Positives = 155/397 (39%), Gaps = 53/397 (13%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            +K +    V E ++A FE E    P    +W R+   +  + + +  +   K  LII   
Sbjct: 2577 SKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAAT 2635

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             ++D   +      +  T+K SA L VE  +              T +N+ VT  Q    
Sbjct: 2636 KLDDIGEYTY----KVATSKTSAKLKVEAVK-----------IKKTLKNLTVTETQDAVF 2680

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              ++T      V W+KNG  ++ + +  I  +   Y+L I      D   Y         
Sbjct: 2681 TVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGA 2740

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR   E V                     +II+  KD    E   + F   +    +P 
Sbjct: 2741 SARLHVETV---------------------KIIKKPKDVTALENATVAFEVSVSHDTVP- 2778

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            V+W+     IKPS   ++      + L +    P D G+Y  V     G++   AKL V 
Sbjct: 2779 VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFV- 2833

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
                 + L     +++I V E + A F+ +++    P++ WL+ G  I  +  F+++ +G
Sbjct: 2834 -----ETLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG 2887

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                L+I NT  ED+  +    T   G  + SA L V
Sbjct: 2888 KLHQLIIMNTSTEDSAEY----TFVCGNDQVSATLTV 2920



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 52/221 (23%), Positives = 90/221 (40%), Gaps = 27/221 (12%)

Query: 265   PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL---INSNKHEIITTHNHT 321
             PP+      N     G + +F V ++ +P P VTW+K+GQ++    N  K+   +     
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 25251

Query: 322   TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
              L + +    D   YT++A N                   Y +D     +T T       
Sbjct: 25252 QLTINSVTTDDDAEYTVVARN------------------KYGEDSCKAKLTVTLHPPP-- 25291

Query: 382   RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
                 ++  L P F ++  + +  EG+   F+ RV+G P P + W  + + +    N +I+
Sbjct: 25292 ----TDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII 25347

Query: 442   VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
                   +AL I +    D+G     A N +G T+ Q  L V
Sbjct: 25348 HEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 3/115 (2%)

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
            Q  ST   + + + +PP FV  L+  T V +G     + +V  +  PN  ++FY +G  +
Sbjct: 88   QATSTAELLVKAETAPPNFVQRLQSMT-VRQGSQVRLQVRVTGI--PNPVVKFYRDGAEI 144

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
            QS+  F I+ +    SL I    PED+G YSV A N++G  TS   + V  +  +
Sbjct: 145  QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 8/161 (4%)

Query: 357  SPTESYVQDQRSQYITDTQQRETEE-RIE--ISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
            S T + V+++R + +   + + TE  R+   +      P  V   ++  V EG+    +C
Sbjct: 859  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
             ++G P P VTW+  D QI    + +I   +SG   LMI      DSG  TC A N++G 
Sbjct: 919  HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977

Query: 474  TAFQCRL--NVIEKEQVVAPKFVERFSTLNVR--EGEPVVL 510
             +  C L   V E+ +       E+F+T   R  E   VV+
Sbjct: 978  VSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVM 1018



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 82/307 (26%), Positives = 134/307 (43%), Gaps = 46/307 (14%)

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
            ++ K+ E   A F+ ++S  P   V W K+ Q L  +++ +I        L + +T+ SD
Sbjct: 3019 KDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 3077

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
            +G YT++A    G  V++  L VE                D + R  ++ +++ EK  A 
Sbjct: 3078 AGKYTVVA----GGNVSTAKLFVEG--------------RDVRIRSIKKEVQVIEKQRAV 3119

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
               +V +D DV              +   E+ + + +R       HK +V E   H + I
Sbjct: 3120 VEFEVNED-DVDAHWY---------KDGIEINFQVQER-------HKYVV-ERRIHRMFI 3161

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +    SD+G  T VA RN+S  T +   +N  E  QV+     +    + V+ G+P    
Sbjct: 3162 SETRQSDAGEYTFVAGRNRSSVTLY---VNAPEPPQVL-----QELQPVTVQSGKPARFC 3213

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            A   G P P+I+W K+   +    + +   DG   TL +  A   DAA Y C A+N  G 
Sbjct: 3214 AMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGV 3273

Query: 572  TATRARL 578
              T A L
Sbjct: 3274 ATTSASL 3280



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 1/121 (0%)

Query: 451   MITNVTLSDSGVVTCVARNKSGET-AFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
             +ITN+T  +  +   VA N+ G +      + ++ K+ V+ P     FS+ +V+ G+ + 
Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16751

Query: 510   LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +     G P P ITW KDG+P+     + +      +TL I      D   Y  T  NV 
Sbjct: 16752 MEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVV 16811

Query: 570   G 570
             G
Sbjct: 16812 G 16812



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 65/239 (27%), Positives = 107/239 (44%), Gaps = 43/239 (17%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFF 962
            +TQ P F  P++  + + EG  A FEA +   G     V W +DG+ +  S+   +   F
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            + G   LTI +VT  ++G Y+ +A N  GQAT++A L +       AE+  P  ++++Q 
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK------AETAPPNFVQRLQS 112

Query: 1023 LEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFN 1082
            +    R   +   +V++T  P         N +V+     +    E QS L         
Sbjct: 113  M--TVRQGSQVRLQVRVTGIP---------NPVVK----FYRDGAEIQSSLDF------- 150

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
              QI+    + +        L IA    EDSG Y+V A N+ G A  +A + V+    +
Sbjct: 151  --QISQEGDLYS--------LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 84/402 (20%), Positives = 159/402 (39%), Gaps = 50/402 (12%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            K ++   ++E E A F+ E     +P  +W  +   ++ SP  +I     K  L + +V 
Sbjct: 4904 KPIEDVTIYEKESASFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLHKVK 4962

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            ++ +      A N    A  +A L V+E         +   F +  ++V V   +  R +
Sbjct: 4963 LDQAGEVLYQALN----AITTAILTVKE---------IELDFAVPLKDVTVPERRQARFE 5009

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
              +T  +  +V W K      PDI    ++    + ++         GK   + IN   +
Sbjct: 5010 CVLT--REANVIWSKG-----PDI----IKSSDKFDIIA-------DGKKHILVIN---D 5048

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
            ++ D E V +      K   +        + + PL+D+ V EG+   F C++  + +  V
Sbjct: 5049 SQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVV 5108

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
             W+K D  +  S+   +S     + L + E   +D    K         ++  A+LKV +
Sbjct: 5109 -WFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKA----QVKELSSTAQLKVLE 5163

Query: 4715 PDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
             D     P  T  L D    E      K +++  +   ++W ++G  I  +P + +  +G
Sbjct: 5164 AD-----PYFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSPKYSIKADG 5216

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATT--AAGQVETSAKLVVKSK 4813
               +L I     +D G + C   T      V   A+L+   K
Sbjct: 5217 LRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIEVEK 5258



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 52/229 (22%), Positives = 96/229 (41%), Gaps = 9/229 (3%)

Query: 2795  CNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVSLDITHTYEEDSGIYTCKATN 2852
             C VE S     ++ W+ + K L     ++  +  D +Y  L I +  E D G Y C+ + 
Sbjct: 26240 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTY-ELKINNLTESDQGEYVCEISG 26298

Query: 2853  SKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPE 2912
               G++ T+        K+I+            ++ ++  E+ + +   P  P+    KP 
Sbjct: 26299 EGGTSKTNLQFMGQAFKSIHEKVSKISETK--KSDQKTTESTVTRKTEPKAPEPISSKP- 26355

Query: 2913  WIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLD 2972
              +I    +   V    +  +  V+   +P     W  +GK + QG ++KL+ D G   L+
Sbjct: 26356 -VIVTGLQDTTVSSDSV-AKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413

Query: 2973  LVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS-KDNLIERTQHPKGTE 3020
             +      DSG+YTC   N  G   +S  +   + KD   ++    K +E
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSE 26462



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 48/196 (24%), Positives = 81/196 (41%), Gaps = 13/196 (6%)

Query: 373  DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
            D Q    +    +  K      ++  +D  VT G+   FDC ++    P V W++  +++
Sbjct: 5680 DFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKL 5738

Query: 433  RDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
                + K++    G  H L + +V L D+G V   A++      F+   N+  KE  V  
Sbjct: 5739 EP--SDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD------FKTHANLFVKEPPV-- 5788

Query: 492  KFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551
            +F +      V EG   VL    V     ++ W K+G  I+ + +  I  DG    L I 
Sbjct: 5789 EFTKPLEDQTVEEGATAVLECE-VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIH 5847

Query: 552  RAKASDAAWYQCTAQN 567
                 D   Y C A++
Sbjct: 5848 DCTPEDIKTYTCDAKD 5863



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 39/121 (32%), Positives = 56/121 (46%), Gaps = 4/121 (3%)

Query: 4596  RCDAECVVSLPATKDKPKPQT-KAANAPPEIIEPLKDK---IVAEGQAIEFSCKIVGKPL 4651
             R  A   V++    +   P T  A N PP I   +  K    V  G  +     + GKP+
Sbjct: 12768 RAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPM 12827

Query: 4652  PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
             PTV W K   L+KP++  +M+   +  TL +     +D GDY   A NS+G  +   KLK
Sbjct: 12828 PTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLK 12887

Query: 4712  V 4712
             V
Sbjct: 12888 V 12888



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 68/300 (22%), Positives = 122/300 (40%), Gaps = 40/300 (13%)

Query: 4442 IKWYR--ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLV 4499
            +KW +  E  P  N   +++  +  K +L I+     D   +   A    G  K  A L+
Sbjct: 6267 LKWTKNGEEVPFDNRVSYRVDKY--KHMLTIKDCGFPDEGEYIVTA----GQDKSVAELL 6320

Query: 4500 VEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIR 4559
            + E          P  F    ++  VT         +++  K  +V W +NG++++   +
Sbjct: 6321 IIE---------APTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKK 6370

Query: 4560 NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
             K  E+DG+   LI++                  + R D EC  +      K + +    
Sbjct: 6371 YKF-EKDGSIHRLIIK------------------DCRLDDECEYACGVEDRKSRARLFVE 6411

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
              P EII P +D + A G  + F  ++  K    VQW + + ++      QM      + 
Sbjct: 6412 EIPVEIIRPPQDILEAPGADVVFLAEL-NKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHR 6470

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGR--VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
            L+I +  P D+G+Y+ +A +   R  + +AA  K+   DQ   +    PL  +V Y+  P
Sbjct: 6471 LQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYP 6530



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 101/468 (21%), Positives = 178/468 (38%), Gaps = 60/468 (12%)

Query: 3992  KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRAT 4051
             K+ C++    D + +V W+F  + L +  ++   Y+ G   +    +   D G Y C+  
Sbjct: 25089 KYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 25147

Query: 4052  NLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPP 4111
             N YG D + A +   G    VYD    + MK I++        +    +++E      PP
Sbjct: 25148 NDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKR--------RTDTMRLLER-----PP 25193

Query: 4112  VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR-YKLTYD---GMYHF 4167
              F       T   GE  RF   +T HP+P V W  +G  I  G    K T++   G+Y  
Sbjct: 25194 EFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQL 25253

Query: 4168  DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRT 4227
              I      D  +  V+             L V          L    RP +         
Sbjct: 25254 TINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTL----RPMF--------- 25300

Query: 4228  ETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQ---QSVKRKKNEEYYNKLQEL 4284
                 ++     +  + Q V     E++   I  P  +W+   Q +    N E  +  + L
Sbjct: 25301 ----KRLLANAECQEGQSVCF---EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH--EGL 25351

Query: 4285  ENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQ----RYEDNLDQTEEVTEQRVQKK 4340
             +   +     L E T  Y +       +T  ++  Q    RY+    +++E  E+ VQK+
Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25411

Query: 4341  VTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTE-TTEIEHKAQTQER 4399
             + +  R+ +    T       VAK+   +  V+    ++ K    E   EIE K   +ER
Sbjct: 25412 IDKTLRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEK--KEER 25469

Query: 4400  VVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
              +  P    +P    +K +   + E ++ +  V     P+  +KWY++
Sbjct: 25470 KLRMPYDVPEP----RKYKQTTIEEDQRIKQFV-----PMSDMKWYKK 25508



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 100/478 (20%), Positives = 181/478 (37%), Gaps = 32/478 (6%)

Query: 4340  KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITR--KITSTETTEIEHKAQTQ 4397
             K  ++ + P+PS    H K V   + K T +E V    ++   KIT     E   +    
Sbjct: 26183 KSPKRVKSPEPS----HPKAVSPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKL 26238

Query: 4398  ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDF 4457
               VVE  V  +K   + K  +  +   H Q  F    DG     I    E+   +   + 
Sbjct: 26239 TCVVESSVLRAKEVTWYKDGKKLKENGHFQ--FHYSADGTYELKINNLTESDQGEYVCEI 26296

Query: 4458  QIHTFSTKSIL-IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
                  ++K+ L  + Q F       + ++E +    K + + V  +   +    I     
Sbjct: 26297 SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV 26356

Query: 4517  TLTA-QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE 4575
              +T  Q+  V+S  + +   K TG       W K+GK +    + K+ E+ G + L I +
Sbjct: 26357 IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 26416

Query: 4576  AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA 4635
                 DSG Y C   NSAG     + C +++ A KD      K +      I P K  +V 
Sbjct: 26417 TDTSDSGLYTCTVKNSAGSV--SSSCKLTIKAIKD--TEAQKVSTQKTSEITPQKKAVVQ 26472

Query: 4636  EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
             E    E S K +      +   K  + +   +  + S+      ++ S A   +    K 
Sbjct: 26473 E----EISQKALRSEEIKMSEAKSQEKLALKE--EASKVLISEEVKKSAATSLE----KS 26522

Query: 4696  VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
             + +    + + A++   T  +    + A +    + + EGQ    K  I       ++W+
Sbjct: 26523 IVHEEITKTSQASEEVRTHAE----IKAFS--TQMSINEGQRLVLKANIAG--ATDVKWV 26574

Query: 4756  REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               G  +  + +++    G++  L I      D G  TC + T  G V+    L +  +
Sbjct: 26575 LNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 26632



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 2/106 (1%)

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            + PP+     +NV V  G+ V L+  ++G     V W +   +++  I  +I  + G   
Sbjct: 894  VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 953

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
            L+I EA+ +DSG++ C A+N AG       C +++  +++  K  T
Sbjct: 954  LMIREAFAEDSGRFTCSAVNEAGTV--STSCYLAVQVSEEFEKETT 997



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 35/146 (23%), Positives = 65/146 (44%), Gaps = 4/146 (2%)

Query: 391   APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
             AP   K  +D     G+  +  C++ GRP P++ W+   +++     +K + ++   H L
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYK-MSSDGRTHTL 24093

Query: 451   MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
              +      D GV TC+A N+ GE     +L +++      P +  +        G  + L
Sbjct: 24094 TVMTEEQEDEGVYTCIATNEVGEVETSSKL-LLQATPQFHPGYPLKEKYYGA-VGSTLRL 24151

Query: 511   NARAVGTPTPRITWQKDGVPIIPNPE 536
             +   +G P P +TW   G  ++ N E
Sbjct: 24152 HVMYIGRPVPAMTW-FHGQKLLQNSE 24176



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIF 823
           T+Q P F +PLQ +  L EG  A FEA ++    P   V W++DG+ I+ S+   +   F
Sbjct: 2   TTQAPTFTQPLQSVVVL-EGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           + G   L I  +   ++G Y+++A N  G+A STA + V A +
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 105/508 (20%), Positives = 194/508 (38%), Gaps = 58/508 (11%)

Query: 4306 GDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQ 4365
            G+ +TS  +  +     +   DQT   +++ V +     P      E    GK + +   
Sbjct: 2561 GENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANP--DSKGEWLRDGKHLPLTNN 2618

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
             +++ +    + I       +  E  +K  T +   +  V+  K     K ++   V E 
Sbjct: 2619 IRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVK---IKKTLKNLTVTET 2675

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            + A F VE     +  ++W +    ++++  + I    T   L I+   + D +V+    
Sbjct: 2676 QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGF-- 2733

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
              R G    SA L VE  +      I  P      +N  V     V  DT       + V
Sbjct: 2734 --RLGRLGASARLHVETVKI-----IKKPKDVTALENATVAFEVSVSHDT-------VPV 2779

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W     +++P  +++++ E   + L++    P D+G+Y  V     G+  C A+  V  
Sbjct: 2780 KWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVE- 2834

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                               I + +K+  V E +   F C++    +P++ W K    I+ 
Sbjct: 2835 ----------------TLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEM 2877

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+ F++      + L I     ED  +Y  V     G   V+A L VT       +   +
Sbjct: 2878 SEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGNDQVSATLTVTP------IMITS 2927

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             L+DI   E     F+  +  +   + +WL+ G  I  T   QM  +     L I N + 
Sbjct: 2928 MLKDINAEEKDTITFEVTVNYE-GISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHF 2986

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             D   +    T  AG+  ++A L V+++
Sbjct: 2987 GDAADY----TFVAGKATSTATLYVEAR 3010



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 3/94 (3%)

Query: 4622  PPEI-IEP-LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             PP I ++P  KD IV   G++ +    I GKP+PT+QW KGD+ +  +   ++  T    
Sbjct: 16043 PPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT 16102

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +L + +A   D G+Y   A N AG  +V   +KV
Sbjct: 16103 SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16136



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 3/107 (2%)

Query: 468   RNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRITW-- 524
             +N+ GE+ +     V+ KE +  P    + S  L V+ G+ + L A   G P P + W  
Sbjct: 11681 KNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTK 11740

Query: 525   QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              KD   +  +P ++I T   +S   + +AK SD   Y  TA N AGS
Sbjct: 11741 DKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGS 11787



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 82/372 (22%), Positives = 149/372 (40%), Gaps = 58/372 (15%)

Query: 2784  VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
             V +EG ++ + C +E + D + ++ W+F  + L +  +Y+ T++     L +    + D 
Sbjct: 25081 VGEEGGHVKYVCKIE-NYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDD 25139

Query: 2844  GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
             G Y CK  N  G  ++   L   G + +Y    +   +   +   + +  RL +  RP  
Sbjct: 25140 GTYRCKVVNDYGEDSSYAELFVKGVREVY---DYYCRRTMKKIKRRTDTMRLLE--RP-- 25192

Query: 2904  PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQG---SRF 2960
                    PE+ +P+  +   V G+  ++   V     P+  + WY +G+ ++ G    ++
Sbjct: 25193 -------PEFTLPLYNKTAYV-GE--NVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKY 25242

Query: 2961  KLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTE 3020
                SD G   L +  V   D   YT  A NK GE        C +K   +  T HP  T 
Sbjct: 25243 TFESDKGLYQLTINSVTTDDDAEYTVVARNKYGED------SCKAK---LTVTLHPPPT- 25292

Query: 3021  GLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSM 3080
                     + +LR              P F  +  +  +  EGQ   +E  +  +G    
Sbjct: 25293 --------DSTLR--------------PMFKRLLAN-AECQEGQSVCFEIRV--SGIPPP 25327

Query: 3081  VIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
              ++W  +G+ +     I  ++       L I  T   D+G Y   ATN  G       L+
Sbjct: 25328 TLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQ 25387

Query: 3140  CVDKSKGQKPRF 3151
              V++ + +K  F
Sbjct: 25388 -VERLRYKKQEF 25398



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 72/337 (21%), Positives = 133/337 (39%), Gaps = 44/337 (13%)

Query: 2256  EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEY 2315
             EG    + C++E  +D + ++ +Y   + L+++ ++ IT++ G   L ++     D G Y
Sbjct: 25084 EGGHVKYVCKIEN-YDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 2316  SVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKI-RELESAEPFKRPEIPEPVTRQ 2374
               K +N  G  +S   + V     +     R   ++KI R  ++    +RP         
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVYDYYCR-RTMKKIKRRTDTMRLLERP--------- 25192

Query: 2375  RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
              P FT PL N      G+   F   +    +P   V W+++ + I+      K + F   
Sbjct: 25193 -PEFTLPLYN-KTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDN-DKKYTF--- 25244

Query: 2435  SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494
                     + D+G+Y    +++  +              +    ++ E   K +     H
Sbjct: 25245 --------ESDKGLYQLTINSVTTDDDAEYT--------VVARNKYGEDSCKAKLTVTLH 25288

Query: 2495  ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
                   P     +P+F ++L   +E  EGQ   +E RV  +  P+L+  W  +G  L +G
Sbjct: 25289 P----PPTDSTLRPMFKRLLAN-AECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLG 25341

Query: 2555  SRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   H+   +  L I   +  D G Y   A N AG
Sbjct: 25342 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 25378



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 2/88 (2%)

Query: 2776  FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
             FIS   +    EG N+ F C +  S +P+ +IEWF NN P+   +    +   +  SL+I
Sbjct: 26639 FISQPRSQNINEGQNVLFTCEI--SGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26696

Query: 2836  THTYEEDSGIYTCKATNSKGSATTSGSL 2863
              +    DSG YT KA N +G  + + SL
Sbjct: 26697 RNASVSDSGKYTIKAKNFRGQCSATASL 26724



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 4722 PALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMIHEGNNAVL 4778
            P  T PL+ +VV EG  A F+  I+    P + W R+G +I  +  P  Q+      A L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             I    + ++G ++ +AT  +GQ  ++A+L+VK++T
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 11/171 (6%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F++   D  V E +M RF+C ++ R   +V WF +  +I+    + I +++     L+I
Sbjct: 5878 EFLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDI-ISKGAVRILVI 5935

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
                L D    +C  R  +  T+    L V+E+E V    F +  + + V E + + L  
Sbjct: 5936 NKCLLDDEAEYSCEVR--TARTSGM--LTVLEEEAV----FTKNLANIEVSETDTIKLVC 5987

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
              V  P   + W K    II      I T+G    L I  A   DA  Y C
Sbjct: 5988 E-VSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 6037



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 1/105 (0%)

Query: 467   ARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
             A+N+ G     Q  + VI K+ V+ P F   F+T  V  GE + ++   +G PTP +TW 
Sbjct: 15626 AQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH 15685

Query: 526   KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             KD VP+     +   +    S L I  A   D   Y     N AG
Sbjct: 15686 KDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 15730



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 42/169 (24%), Positives = 71/169 (42%), Gaps = 4/169 (2%)

Query: 1520  RAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPI 1579
             R+ + V ++    R    +  DI    ++     + Q   +R KY            AP 
Sbjct: 25820 RSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSER-KYEVLSQQPFTLDHAPR 25878

Query: 1580  CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDI 1639
              T  +++  +  GQ   F   +   S  T +V+WYHN   L+  S+   TN  G + L+I
Sbjct: 25879 ITLRMRSHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936

Query: 1640  MSCLPEDSGTYTCRAINALGEAVT-SGIAIVHSKKSIYLESQHEGALPR 1687
             + C  +DSGTY     N  GEA   + + +     + Y   + +  +PR
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPR 25985



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 44/148 (29%), Positives = 67/148 (45%), Gaps = 13/148 (8%)

Query: 211  NGTDHSSTDDFKV--DTFEYRLLREVSFRESITKRYV-------GESDVQISTEIDRSL- 260
            +G DHS    F    D  EY  +    + ++I   Y+       G  D +  + + +SL 
Sbjct: 3508 DGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLE 3567

Query: 261  --GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
              G   PP   ++ +  +  +G  A F+  + G P P VTWFK  ++L  S  + II   
Sbjct: 3568 KLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNP 3627

Query: 319  NHT-TLRVRNTQKSDSGHYTLLAENPNG 345
            N + T  V + Q+ DSG Y   AEN  G
Sbjct: 3628 NGSGTFIVNDPQREDSGLYICKAENMLG 3655



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 5/125 (4%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            +I  K    + TE E         + GP     PP F K+++P R  +   A FE    G
Sbjct: 3545 KINSKGEGHKDTETESAVAKSLEKLGGPC----PPHFLKELKPIRCAQGLPAIFEYTVVG 3600

Query: 4437 EPLPLIKWYRENFPIKNSPDFQ-IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            EP P + W++EN  +  S  +  IH  +     I+     EDS ++   AEN  G + C+
Sbjct: 3601 EPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCA 3660

Query: 4496 ANLVV 4500
            A L+V
Sbjct: 3661 AELLV 3665



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 54/186 (29%), Positives = 86/186 (46%), Gaps = 14/186 (7%)

Query: 388  KALAPQFVKVCQDRDVTE----GKMTRFDCRVTGRPYPEVT-WFINDRQIRDDYNHKILV 442
            KA+  +FVK  +D  +TE    G    F+C V+  P   +T W  +   IR+   H+ + 
Sbjct: 4614 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIA 4671

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
             +  +  L I +V LSD+G  TCV R  + E     +L V+E+  V   K +E    + V
Sbjct: 4672 -DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKL-VVEELPVRFVKTLE--EEVTV 4727

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWY 561
             +G+P+ L+          + W+KDG  ++  P  +     G    L I  A  +DA  Y
Sbjct: 4728 VKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTY 4785

Query: 562  QCTAQN 567
              T +N
Sbjct: 4786 TVTVEN 4791



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 48/200 (24%), Positives = 80/200 (40%), Gaps = 3/200 (1%)

Query: 4614  PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMS 4672
             P++      P   E L++  V         CK+ G P P V+WY+ G ++I     +++ 
Sbjct: 24422 PKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQ 24481

Query: 4673  RTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
                  Y  L I+    +D   Y+  A N  G V+  A L+V  P +      L  +  + 
Sbjct: 24482 EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVH 24541

Query: 4732  VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE-EDTGT 4790
                G+    K   + K  P I W +   LI     +Q+I   +   L+  N  E +D G 
Sbjct: 24542 ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGF 24601

Query: 4791  FTCRATTAAGQVETSAKLVV 4810
             +   A    G  + + +L V
Sbjct: 24602 YVVCAKNRFGIDQKTVELDV 24621



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765
            TQAP FT P++ + V E   A FEA +   G P   V W R+G  I  S        F  
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSD 60

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            G   L +  V   +SG Y+ +A N  G+A +++ L V+++ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 30/95 (31%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++  V +G  V L+  +T + +P   V++Y +G  +Q    F+ + +    +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPNPV--VKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             I  AY ED+GTY   ATN+VG A +T+ + V  +
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 45/187 (24%), Positives = 91/187 (48%), Gaps = 15/187 (8%)

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
            E+++P++D  + E ++  F  +I    +P  QW    +L++PS   ++     +  L + 
Sbjct: 4901 ELLKPIEDVTIYEKESASFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLH 4959

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
            +   +  G+   V Y +   +T A  L V + +    L    PL+D+ V E + A+F+  
Sbjct: 4960 KVKLDQAGE---VLYQALNAITTAI-LTVKEIE----LDFAVPLKDVTVPERRQARFECV 5011

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            +T +    + W +   +I  +  F +I +G   +L+I ++  +D G +T       G+ +
Sbjct: 5012 LTREAN--VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAE---VEGK-K 5065

Query: 4804 TSAKLVV 4810
            TSA+L V
Sbjct: 5066 TSARLFV 5072



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 52/230 (22%), Positives = 93/230 (40%), Gaps = 15/230 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+T G   +     ++++D    Y        T+ ++++ E  LA +F+   Q+ ++ EG
Sbjct: 6013 ILTEGRKRILVIQNAHLEDA-GNYNCRLPSSRTDGKVKVHE--LAAEFISKPQNLEILEG 6069

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            +   F C ++   +P V W  +D+ +     + ++  +     L++ + TL D G    +
Sbjct: 6070 EKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIA-DGKKRVLVVKDATLQDMGTYVVM 6127

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
                 G       L VIEK ++V P          V+E + VV N   V T   +  W +
Sbjct: 6128 V----GAARAAAHLTVIEKLRIVVP-----LKDTRVKEQQEVVFNCE-VNTEGAKAKWFR 6177

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
            +   I  + +  I       TL I  A   D A Y  +  N  G     A
Sbjct: 6178 NEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSA 6227



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 1/93 (1%)

Query: 482   VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             VI K+  + P     F+T +++ GE + +    +G P P I+W KDG P+     + +  
Sbjct: 17806 VIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEE 17865

Query: 542   DGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
                ++ L I      D   Y  TA N AG TAT
Sbjct: 17866 TATSTVLHIKEGNKDDFGKYTVTATNSAG-TAT 17897



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%)

Query: 266   PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
             P I ++ ++   + G  AQ   Q+ G P P + W++ G+ LI S K+++ +     TL V
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095

Query: 326   RNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
                ++ D G YT +A N  G + TS  L +++
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 44/186 (23%), Positives = 77/186 (41%), Gaps = 8/186 (4%)

Query: 3054  FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGT 3113
             F   + I+EGQ    +A++    D    ++W  NG  +  S   R   +     L I   
Sbjct: 26547 FSTQMSINEGQRLVLKANIAGATD----VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQA 26602

Query: 3114  KTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173
                D G  +C +  K G  +    L  + K     P F +  ++ + + +GQ+  F C +
Sbjct: 26603 SHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDAPAFISQPRS-QNINEGQNVLFTCEI 26660

Query: 3174  VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                 +P  +IEW+ N  P+  S+ +          L+I      DSG+Y  +A N  G+ 
Sbjct: 26661 S--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQC 26718

Query: 3234  FTRATI 3239
                A++
Sbjct: 26719 SATASL 26724



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 36/114 (31%), Positives = 49/114 (42%), Gaps = 2/114 (1%)

Query: 49   TTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK 108
            T ++ S     P       E + PIF +   NA  + G  A     + G P P + W   
Sbjct: 3434 TLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFN 3493

Query: 109  KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
               L     Y   ++    D SL+I      DEGEYTC A N YG+ ICS Y++
Sbjct: 3494 GVLLTPSADYKFVFDGD--DHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLK 3545



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 1/92 (1%)

Query: 67   GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
            G P PP F +  K  R AQG  A FE  + G P P V+W ++   L     Y++ +N   
Sbjct: 3570 GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHN-PN 3628

Query: 127  GDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            G  + ++      D G Y C A N  GE+ C+
Sbjct: 3629 GSGTFIVNDPQREDSGLYICKAENMLGESTCA 3660



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 125/638 (19%), Positives = 243/638 (38%), Gaps = 50/638 (7%)

Query: 1174 KSKPV-FVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            K  PV F +PL +   V EG    LEC +        +V+WF NG  +    +++   D 
Sbjct: 5784 KEPPVEFTKPLEDQT-VEEGATAVLECEVSR---ENAKVKWFKNGTEILKSKKYEIVAD- 5838

Query: 1233 GFVALDIIH-ATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ---NEQAIEQI 1288
            G V   +IH  T  D   YT  A +   S + + +   +E    +TD Q    E A  + 
Sbjct: 5839 GRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFEC 5898

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
            +L  + A+  K  ++   + +  ++         +   N   +C L          E+ C
Sbjct: 5899 ELSRENAK-VKWFKDGAEIKKGKKYDIISKGAVRILVIN---KCLLDD------EAEYSC 5948

Query: 1349 NGKPIKTGHRFRPAYEFDYVALDL--LSVYPEDSGVYTCQATNQLGEAVTSCALRVI--- 1403
              +  +T        E      +L  + V   D+    C+ +    E +       I   
Sbjct: 5949 EVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIET 6008

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYK------KTDIIDESVTIKPRFVTRPKSIENVI 1457
             + +++ E +    + +  +LED   Y       +TD   +   +   F+++P+++E ++
Sbjct: 6009 GRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLE-IL 6067

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EG+   F C    ++  +  V+W ++ + +  G ++  I D     L + D   +D G Y
Sbjct: 6068 EGEKAEFVCS---ISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 6124

Query: 1518 TCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
                V +VG    +  LT      IV   ++    EQ +V+ +               + 
Sbjct: 6125 ----VVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEE 6180

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSD-ATLKVE-WYHNNKPLKSGSR-FTETNNFGF 1634
             I  +S K + +++        R   + D A   V    H  + +KS +    E  +   
Sbjct: 6181 AIFDSS-KYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRI 6239

Query: 1635 V-ALDIMSCLPEDSGTYTCRA--INALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN-Q 1690
            V  L  +  + + S T+ C+   +N   +   +G  +    +  Y   +++  L   +  
Sbjct: 6240 VEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCG 6299

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ-AAHFEARLI--PVGDPKLRVEWL 1747
              D  +Y   + QD+ + +  +   P + +   E+Q    F+  +    +   K  V+W 
Sbjct: 6300 FPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWY 6359

Query: 1748 RNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785
            RNG  I+   +     D     L +K    +D   Y C
Sbjct: 6360 RNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC 6397



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 42/160 (26%), Positives = 77/160 (48%), Gaps = 12/160 (7%)

Query: 1792 GEAVTSSTL------FVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQA 1843
            G+ +++STL      F   +A L + +  +  S    ++    S +     ++ V    A
Sbjct: 43   GQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102

Query: 1844 P-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            P  F+ +L   T + +G     + R+   P+P   V++Y +G  +QS   ++ S +    
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPNPV--VKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +L I   Y EDSG Y+  A N++G+A S+  L VQ +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 11/179 (6%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F K  +D+ V EG     +C V+ R   +V WF N  +I     ++I V +     L+I
Sbjct: 5789 EFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEI-VADGRVRKLVI 5846

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             + T  D    TC A  K  +T+  C LNV+        +F+   + L VRE E      
Sbjct: 5847 HDCTPEDIKTYTCDA--KDFKTS--CNLNVVPPHV----EFLRPLTDLQVREKEMARFEC 5898

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              +     ++ W KDG  I    +  I + G    L I +    D A Y C  +    S
Sbjct: 5899 E-LSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTS 5956



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 44/200 (22%), Positives = 81/200 (40%), Gaps = 15/200 (7%)

Query: 1606  DATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG 1665
             D + +V WY   + L++  ++  T   G   L +      D GTY C+ +N  GE  +  
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 1666  IAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAEN 1725
                V   + +Y +      + ++ +  DT +         ++ + P FT+P+ +      
Sbjct: 25158 ELFVKGVREVY-DYYCRRTMKKIKRRTDTMR---------LLERPPEFTLPLYNKTAYVG 25207

Query: 1726  QAAHFEARLIPVGDPKLRVEWLRNGVPIEASN---RLTTMHDFGYVALNMKYVNPEDSGT 1782
             +   F   +     P+  V W ++G  I+  +   + T   D G   L +  V  +D   
Sbjct: 25208 ENVRFGVTI--TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAE 25265

Query: 1783  YTCRAINELGEAVTSSTLFV 1802
             YT  A N+ GE    + L V
Sbjct: 25266 YTVVARNKYGEDSCKAKLTV 25285



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 2/123 (1%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH--EIITTHNHTTL 323
           P   Q  ++  + EG+ A F+  +SG P P V+WF++GQ +  S     +I  +     L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +    K++SG Y+L A N +G   ++  L V++ T      QR Q +T  Q  +   ++
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125

Query: 384 EIS 386
            ++
Sbjct: 126 RVT 128



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 26/66 (39%), Positives = 37/66 (56%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G+     V +SG P P+VTW     RL  +++  I TT + TTL V+++ + DSG Y L 
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22224

Query: 340   AENPNG 345
              EN  G
Sbjct: 22225 LENTAG 22230



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 2/105 (1%)

Query: 1296  RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
             R    ++  +T  +AP   + + ++ T  G    L C++  VG     ++W+  GK +  
Sbjct: 24021 RTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQ 24078

Query: 1356  GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
               +++ + +     L +++   ED GVYTC ATN++GE  TS  L
Sbjct: 24079 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 4/85 (4%)

Query: 1854  TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
             TKL  G++A   C+I   P P+  ++WY  GK L    +Y+ S+D     L ++T   ED
Sbjct: 24047 TKL--GEAAQLSCQIVGRPLPD--IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQED 24102

Query: 1914  SGEYTCKAINNLGQAVSSIRLNVQS 1938
              G YTC A N +G+  +S +L +Q+
Sbjct: 24103 EGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 3/113 (2%)

Query: 2622  KEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKN 2681
             KE  +    ++ +   +  AP F +  +S + + EGQ+V    ++    +P+ +IEWFKN
Sbjct: 26617 KEGIVKCQYDLTLSKELSDAPAFISQPRSQN-INEGQNVLFTCEISG--EPSPEIEWFKN 26673

Query: 2682  GVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
              + ++  + +  +    + +L I +    DSG YT KA N  G+  +TAS+ +
Sbjct: 26674 NLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 4/140 (2%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V  G    F C ++    P +R  WF  GR      +    +     +L+I      D
Sbjct: 4346 LEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVD 4403

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAK-RDIVLESQLPQGMSGEKIKELERGRISDAPKEE 3823
             GEYTC+A+N++GS + TA +T +    +  +   LP+     K + + +  +   P+EE
Sbjct: 4404 CGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEE 4463

Query: 3824 PIVSTPPKFITQIKSHTVEE 3843
                  PK + ++K   V E
Sbjct: 4464 E-PKVEPKKLEKVKKPAVPE 4482



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 53/204 (25%), Positives = 83/204 (40%), Gaps = 19/204 (9%)

Query: 3449  DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
             D + +V WY+  + L+   ++    + G  IL +      D G Y C+  N+YGE  + A
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157

Query: 3509  SMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI 3568
              + V+G R +            T+ KI   +  + T+  L        PPEFT    +  
Sbjct: 25158 ELFVKGVREV-----YDYYCRRTMKKI---KRRTDTMRLLE------RPPEFTLPLYNKT 25203

Query: 3569  LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI---NDFGFVILEIGGVYQR 3625
                  +  F    I V+     V W+ +G+ +  G   K     +D G   L I  V   
Sbjct: 25204 AYVGENVRFGV-TITVHPEP-HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25261

Query: 3626  DAGLYTCKATNRHGEATVSCKLQV 3649
             D   YT  A N++GE +   KL V
Sbjct: 25262 DDAEYTVVARNKYGEDSCKAKLTV 25285



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 4/95 (4%)

Query: 769   RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGY 827
             RP F R L +  E QEG++  FE +++ +  PT++  W KDG+P++    I  I     Y
Sbjct: 25297 RPMFKRLLAN-AECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDY 25353

Query: 828   VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
              +L+I     ED G Y V A N  G     A ++V
Sbjct: 25354 YALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 58/228 (25%), Positives = 97/228 (42%), Gaps = 14/228 (6%)

Query: 352  YLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRF 411
            +L++ +   S  +D     + D   + T + I   E A+  +FVK  QD +V E      
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIV--EGAVV-EFVKELQDIEVPESYSGEL 2240

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V+     E  W+ ND +++ +  + I  +  G   L + +VT  D G  + V   K 
Sbjct: 2241 ECIVSPENI-EGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFVIDGKK 2298

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
                  C+L +  K + +A   ++  S   V EG+ V L  + V   +    W KDG  +
Sbjct: 2299 TT----CKLKM--KPRPIA--ILQGLSDQKVCEGDIVQLEVK-VSLESVEGVWMKDGQEV 2349

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             P+  + I  D  +  L I      DA  Y  T   +  ST+ R  +Y
Sbjct: 2350 QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 100/413 (24%), Positives = 169/413 (40%), Gaps = 43/413 (10%)

Query: 1262 HTSAIVRVIERSDIVTDTQNEQAIEQI-QLLEDAARRTKQVREDITVMQA-PQFSRALHN 1319
            HT+  V + +     + T  + +I+   Q+  +A   + + +  +TV++  P F+  L +
Sbjct: 5472 HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAK--LTVLEGDPYFTGKLQD 5529

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
               VE   V L+C +         V+WF +GK IK         +     L L      D
Sbjct: 5530 YTGVEKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKTDGKKRMLILKKALKSD 5586

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DTSRYKKTDIIDE 1438
             G YTC      G   TS  L +   +D  ++   P  L  ++ +E +T+R++ T+I ++
Sbjct: 5587 IGQYTCDC----GTDKTSGKLDI---EDREIKLVRP--LHSVEVMETETARFE-TEISED 5636

Query: 1439 SV----TIKPRFVTRPKSIENVIEGQ-H--VHFECKLEPVTD-----SNLKVEWFKNGQP 1486
             +     +K   + +    E   EG+ H  V   C+L+         +N+K       +P
Sbjct: 5637 DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKP 5696

Query: 1487 VTIGHRFRPIHDF----GYVALDIIDLIAEDSGI-YTCRAVNLVGTDEVSCRLTCRSTTD 1541
              IG   RP+ D     G  A    +L  ED  + +  +   L  +D+V  R   +  T 
Sbjct: 5697 RVIG-LLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTL 5755

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
             +R  + E   E +Q+     K H    V E   +    T  L++  ++EG  A  E   
Sbjct: 5756 TLRDVKLEDAGE-VQLTAKDFKTHANLFVKEPPVEF---TKPLEDQTVEEGATAVLE--- 5808

Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
              VS    KV+W+ N   +    ++    +     L I  C PED  TYTC A
Sbjct: 5809 CEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 2/117 (1%)

Query: 4598  DAECVVSLPATKDKPKPQTKAANAPPEIIEP-LKDKIVAE-GQAIEFSCKIVGKPLPTVQ 4655
             +A   +S P+    P         P   ++P  +D IV   G+       + GKPLPT++
Sbjct: 17102 NAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIE 17161

Query: 4656  WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             W +GDK I+ S   ++  T  +  L + +A   D G Y   A N AG  +    +KV
Sbjct: 17162 WLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV 17218



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +Q G D + ++ + G PRP ++W K+G+ L  + +  +  T   T L ++   K D G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885

Query: 337   TLLAENPNGCIVTS-GYLAVESP 358
             T+ A N  G    +   + +E P
Sbjct: 17886 TVTATNSAGTATENLSVIVLEKP 17908



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)

Query: 1709  QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             +AP     MKD+     +AA    ++  VG P   ++W R G  +  S +     D    
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH 24091

Query: 1769  ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
              L +     ED G YTC A NE+GE  TSS L +Q+
Sbjct: 24092 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 49/228 (21%), Positives = 89/228 (39%), Gaps = 15/228 (6%)

Query: 2389  QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448
             +EG    + C+ I   D + +V W+   + +E+S +   T++ G   + +  +   D+G 
Sbjct: 25083 EEGGHVKYVCK-IENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 25141

Query: 2449  YMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKP 2508
             Y C+  N  GE              +  +      MKKI++  +    R  E   EF  P
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVREV-YDYYCRRTMKKIKR--RTDTMRLLERPPEFTLP 25198

Query: 2509  IFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG---SRFRTTHDFGF 2565
             ++ +        + G++  +   +    +P +   WY +G ++K G    ++    D G 
Sbjct: 25199 LYNKT------AYVGENVRFGVTITVHPEPHV--TWYKSGQKIKPGDNDKKYTFESDKGL 25250

Query: 2566  VTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRP 2613
               L INSV  +D   Y   A N+ G                 D  +RP
Sbjct: 25251 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 25298



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 1/102 (0%)

Query: 4404  PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTF 4462
             P   +  P+F + +      E +   FE+   G P P +KW ++  P+   P+ + IH  
Sbjct: 25291 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEG 25350

Query: 4463  STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR 4504
                  L IR    ED+  +   A N  G+  C A+L VE  R
Sbjct: 25351 LDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLR 25392



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%)

Query: 2124  GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
             G    F   V+  + P   + W+HNG +++   +   T+  G + L+IL  + +DSGTY 
Sbjct: 25891 GQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 25948

Query: 2184  CKATNKLGEAVNTCTLKVAG 2203
                TN  GEA +  TL V G
Sbjct: 25949 AVCTNYKGEASDYATLDVTG 25968



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 28/98 (28%), Positives = 55/98 (56%), Gaps = 2/98 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L ++   +G+ V L+ R+  + +    V+++ +G  I++   F+ + E D  +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPNPV--VKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
             +   YPEDSG Y+  ATN +G A ++  L V  ++++
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 4737 PAQFKTQITSKIKPT--IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            PA F+ ++T    PT  ++WL +G  +      +MI+E     L  G  Y  D+G  TCR
Sbjct: 1673 PAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCR 1732

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            AT   G   TSA L+VK +
Sbjct: 1733 ATNKYGTDHTSATLIVKDE 1751



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 25/83 (30%), Positives = 42/83 (50%)

Query: 263   VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
             V  P +     +  +Q G D + +V +SG P+P +TW K+G  L  + +  +  + + TT
Sbjct: 16730 VIEPDVKPAFSSYSVQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16789

Query: 323   LRVRNTQKSDSGHYTLLAENPNG 345
             L ++ T K D G Y +   N  G
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVG 16812



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L ++  +R+G     + R+T    PN  V++Y +G  +++   F+   +     
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGI--PNPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            L I+  YPEDSG Y   A N+ G A +TA + VQG+  +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 93/202 (46%), Gaps = 33/202 (16%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK-HEIITTHNHTTLR 324
            PKI ++ ++  + +G+DA F+V++ G P P   W+KNG ++  S++ +      N   L 
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +R+    DS    + A N          +A E+ + +++  Q  Q IT TQ+ +      
Sbjct: 2092 IRDVTAEDSASIMVKAIN----------IAGETSSHAFLLVQAKQLITFTQELQD----- 2136

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                        V +++D     M  F+C  T  P+ +V W+ +  ++ +   ++ + ++
Sbjct: 2137 -----------VVAKEKDT----MATFECE-TSEPFVKVKWYKDGMEVHEGDKYR-MHSD 2179

Query: 445  SGNHALMITNVTLSDSGVVTCV 466
               H L I  +  SD+   +CV
Sbjct: 2180 RKVHFLSILTIDTSDAEDYSCV 2201



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 40/171 (23%), Positives = 64/171 (37%), Gaps = 9/171 (5%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVV 4500
            + WY EN  + +   F+         L+I +V  ED    +   A N  G    SA L V
Sbjct: 4272 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331

Query: 4501 EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN 4560
             ++          P      + + V  G L +   ++     +   W K G+++    + 
Sbjct: 4332 VKR--------AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4383

Query: 4561 KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
             I       +L IL     D G+Y C A N  G   C A   V++P  + K
Sbjct: 4384 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKK 4434



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 5/195 (2%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
             ET E +++SE  L P  V +    DVT    T    +       ++T ++ + Q +    
Sbjct: 18788 ETTEPVKVSEPPLPPGRVTLV---DVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEK 18844

Query: 438   HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGET-AFQCRLNVIEKEQVVAPKFVER 496
                        A  I+ +T  +  V    A N+ G +   Q  + VI ++  + P     
Sbjct: 18845 WSTCTQVKTLEAT-ISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELP 18903

Query: 497   FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
             F T NV+  E + ++    G P   + W+KDG  +     + + +    ++L I  A   
Sbjct: 18904 FHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKE 18963

Query: 557   DAAWYQCTAQNVAGS 571
             D   Y+    N AGS
Sbjct: 18964 DVGTYELCVSNSAGS 18978



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 1/84 (1%)

Query: 274   NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH-NHTTLRVRNTQKSD 332
             N++ QEG    F++++SG P P + W K+GQ L      EII    ++  L +R+T   D
Sbjct: 25306 NAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPED 25365

Query: 333   SGHYTLLAENPNGCIVTSGYLAVE 356
             +G+Y + A N  G      +L VE
Sbjct: 25366 TGYYRVTATNTAGSTSCQAHLQVE 25389



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 3/99 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L S+  +++G +   + RV  I +P   + ++ +G +I++   ++ + +    +
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPNP--VVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
            L I   Y EDSGTY   ATN +G A +T  L V G   +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 70/271 (25%), Positives = 100/271 (36%), Gaps = 31/271 (11%)

Query: 2339 SIISESQRPEGLEKI--RELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTAH 2395
            SI   + R E  E +  RE +  E  + P   E PVT   P     L+N+  I EG++  
Sbjct: 859  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTP--PTLVSGLKNVTVI-EGESVT 915

Query: 2396 FDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
             +C +     PT  V W+R +  IE S     T   G   + I     ED G + C A N
Sbjct: 916  LECHISGYPSPT--VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVN 973

Query: 2456 LLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLT 2515
              G                + ET         +K     +R  E  D        T+   
Sbjct: 974  EAGTVSTSCYLAVQVSEEFEKET-----TAVTEKFTTEEKRFVESRDVVMTDTSLTEEQA 1028

Query: 2516 GPSE--------------LWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            GP E              L EG    +  +V   G+P     W  +GV L  G R++ ++
Sbjct: 1029 GPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSY 1086

Query: 2562 D--FGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +   G   L I+   A+DAG Y     N+ G
Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHG 1117



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 25/72 (34%), Positives = 35/72 (48%)

Query: 4633  IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             I   G  I+    ++G+P PTV W KGD+++K ++      TA    L I+E    D G 
Sbjct: 14579 IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14638

Query: 4693  YKCVAYNSAGRV 4704
             Y   A N  G V
Sbjct: 14639 YPLTARNIVGEV 14650



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 49/204 (24%), Positives = 84/204 (41%), Gaps = 12/204 (5%)

Query: 4411  PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
             P   K+M+       E A+   +  G PLP IKWYR    +  S  +++ +      L +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095

Query: 4471  RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                  ED  V+  +A N  G  + S+ L+++   +        P + L  +      G  
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ------FHPGYPLKEKYYGAV-GST 24148

Query: 4531  VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ--DSGKYECVA 4588
             +RL     G +P+      +G+K+  +  N  +E    YT L+++   +   +GKY+   
Sbjct: 24149 LRLHVMYIG-RPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQL 24207

Query: 4589  INSAGEARCDAECVVSLPATKDKP 4612
              N  G    DA   V +    DKP
Sbjct: 24208 SNVFGTV--DAILDVEIQDKPDKP 24229



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 2/74 (2%)

Query: 2926  GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
             G+   L  Q+  +  PD+K  WY  GK L Q  ++K++SD    TL ++   + D G+YT
Sbjct: 24050 GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 2986  CKAYNKRGEAFTSS 2999
             C A N+ GE  TSS
Sbjct: 24108 CIATNEVGEVETSS 24121



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 53/216 (24%), Positives = 83/216 (38%), Gaps = 17/216 (7%)

Query: 650   EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEY 709
             EGG + +  +IE   D + ++ W    + +E S ++   +  G   L +  +   D G Y
Sbjct: 25084 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 710   TCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQR 769
              C+ V+  G   + A L V             E   Y  +     K + +        + 
Sbjct: 25143 RCKVVNDYGEDSSYAELFV---------KGVREVYDYYCR-RTMKKIKRRTDTMRLLERP 25192

Query: 770   PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG---RPITASSRITSIFNFG 826
             P+F  PL +      G N  F   +T   +P   V WYK G   +P     + T   + G
Sbjct: 25193 PEFTLPLYN-KTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 25249

Query: 827   YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                L I  +  +D   YTV A NK GE    A + V
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 3/97 (3%)

Query: 2638  VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
             +  AP  T  ++S+ ++  GQ+      V+ +  P  +++W+ NGV L   +++  T   
Sbjct: 25873 LDHAPRITLRMRSH-RVPCGQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTS 25929

Query: 2698  GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             G++TL I     DDSG Y    TN  GEA   A++ +
Sbjct: 25930 GVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 7/117 (5%)

Query: 1289 QLLEDAARRTKQVREDITVMQAPQ--FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEW 1346
            +LLE+       V  DI+  +A +  F   + N   +EG  V   C++   G    ++ W
Sbjct: 1223 ELLEEDGEEKMAV--DISESEAVESGFDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAW 1278

Query: 1347 FCNGKPIKTGHRFRPAYEFD-YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            + +GK IK G R++  +  D   +L +  V PED G+YT  A+N  G A+ S  L V
Sbjct: 1279 YKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1335



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 7/86 (8%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF---GFAALDILTVYG 1911
            ++ EG    + C++  YP P  ++ WY +GK ++ G RY+   DF   G A+L I  V  
Sbjct: 1255 RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLP 1310

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            ED G YT  A N  G A+ S +L V+
Sbjct: 1311 EDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 96/395 (24%), Positives = 167/395 (42%), Gaps = 34/395 (8%)

Query: 1424 LEDTSRYK-KTDIIDESVTIKPRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLK-VE 1479
            L+D   Y  K      S  +K   V   K+++N  V E Q   F  +L   T  N+K V+
Sbjct: 2637 LDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL---THPNVKGVQ 2693

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W KNG  +    ++         +L I +    D  +Y  R    +G    S RL    T
Sbjct: 2694 WIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFR----LGRLGASARLHVE-T 2748

Query: 1540 TDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599
              I++  ++   LE   V  + S  H T  V        I   S K+  + E +      
Sbjct: 2749 VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEI-KPSDKHRLVSERKVHKLML 2807

Query: 1600 RLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPED-SGTYTCRA--I 1655
            + I  SDA    E+      L+  ++ F ET +      +I   +PE  + ++ C     
Sbjct: 2808 QNISPSDAG---EYTAVVGQLECKAKLFVETLHITKTMKNIE--VPETKTASFECEVSHF 2862

Query: 1656 NALGEAVTSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV---ITQAP 1711
            N     + +G+ I  S+K  I ++ +    +      ED+++Y      D+V   +T  P
Sbjct: 2863 NVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTP 2922

Query: 1712 VF-TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            +  T  +KDI   E     FE   + V    +  +WL+NGV I+++++          +L
Sbjct: 2923 IMITSMLKDINAEEKDTITFE---VTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSL 2979

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            N++ V+  D+  YT  A    G+A +++TL+V+++
Sbjct: 2980 NIRNVHFGDAADYTFVA----GKATSTATLYVEAR 3010



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 42/175 (24%), Positives = 76/175 (43%), Gaps = 6/175 (3%)

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            + L DS +      + V    AP    ++  P +++ G  A + C I+  P  N+R +W+
Sbjct: 4315 EALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSAP--NVRFQWF 4371

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG--QAVSSIRLNVQSK 1939
              G+ +    +    +    ++L+IL     D GEYTCKA N  G     +++ + V   
Sbjct: 4372 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGG 4431

Query: 1940 ESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHP 1994
            E  +R    E   E  + +   S  ++  +++   VE  +  K +K   V E  P
Sbjct: 4432 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEK-VKKPAVPEPPP 4485



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 45/198 (22%), Positives = 82/198 (41%), Gaps = 5/198 (2%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRDVTEGKMT-RFDCRVTGRPYPEVTWFINDRQIRDDY 436
             ET E + I E    P+  +  + ++VT+  +T  ++          + + +  R I  + 
Sbjct: 10206 ETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10265

Query: 437   NHKILVNESGNHALMITNVTLSDSGVVTCVARN--KSGETAFQCRLNVIEKEQVVAPKFV 494
              HK+  +   +    +  +   D+      A N    G+ +F C   +  K+++  P   
Sbjct: 10266 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSF-CTKPITCKDELAPPTLH 10324

Query: 495   ERF-STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
               F   L +R GE   L  R  G P P+++W KD   ++ +    I T      L+  +A
Sbjct: 10325 LDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKA 10384

Query: 554   KASDAAWYQCTAQNVAGS 571
             K SD+  Y    +N  GS
Sbjct: 10385 KRSDSGKYCVVVENSTGS 10402



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQKPRNSK---LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             V PP+I+  P+      +  G   +    + G P P + W K  Q L N+ + EI +T  
Sbjct: 16041 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDF 16100

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
              T+L V++  + DSG+Y L A+N  G
Sbjct: 16101 ATSLSVKDAVRVDSGNYILKAKNVAG 16126



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 23/70 (32%), Positives = 40/70 (57%)

Query: 2938  KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
             ++ P  +++WY NG  L++ S+   T+  G +TL+++D +  DSG Y     N +GEA  
Sbjct: 25901 QSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASD 25960

Query: 2998  SSTVYCTSKD 3007
              +T+  T  D
Sbjct: 25961 YATLDVTGGD 25970



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 2/130 (1%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           Q   T E +  +E A  P FV+  Q   V +G   R   RVTG P P V ++ +  +I+ 
Sbjct: 88  QATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVKFYRDGAEIQS 146

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             + +I   E   ++L+I      DSG  +  A N  G       L V  +E+V A K  
Sbjct: 147 SLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTK 205

Query: 495 ERFSTLNVRE 504
              ST  + E
Sbjct: 206 TIVSTAQISE 215



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 2/125 (1%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +PP   Q+ ++  +++G+  + QV+++G P P V ++++G  + +S   +I    +  +L
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +      DSG Y++ A N  G   ++  L V+   E  V  ++++ I  T Q     + 
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG--EEEVPAKKTKTIVSTAQISESRQT 219

Query: 384 EISEK 388
            I +K
Sbjct: 220 RIEKK 224



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F++ LQ +  +++G     + ++T + +P   V++Y+DG  I +S            S
Sbjct: 104 PNFVQRLQSM-TVRQGSQVRLQVRVTGIPNPV--VKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I     ED+G+Y+V A N +G A STA + V     V A
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPA 201



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 4/114 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYRTSNDFG 1900
            +AP+   ++   T + +G  AH+  R+   PDP    EWY NG K+ +S   Y    +  
Sbjct: 2030 EAPKIFERIQSQT-VGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERSDRIYWYWPEDN 2086

Query: 1901 FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
               L I  V  EDS     KAIN  G+  S   L VQ+K+ I    + +  + K
Sbjct: 2087 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAK 2140



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 41/115 (35%), Positives = 54/115 (46%), Gaps = 10/115 (8%)

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFS----TLNVREGEPVVLNARAVGTPTPRI 522
            A N+ GE+     LNV+ ++  V P    R S    T+ V+ GEPV + A   G P P+I
Sbjct: 8874 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 8933

Query: 523  TWQKDGVPI-IPNPELRIHTD----GGAST-LDIPRAKASDAAWYQCTAQNVAGS 571
             W K+   I  P   L+I  +      A T L IP+A   D   Y  TA N  GS
Sbjct: 8934 EWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS 8988



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 53/203 (26%), Positives = 80/203 (39%), Gaps = 13/203 (6%)

Query: 4514  PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
             P   L A  +   S  L  L     G   ID Y +   ++ QP  R          +L++
Sbjct: 12304 PPRKLEATEMTKNSATLAWLPPLRDGGAKIDGYIISYREEEQPADRWTEYSVVKDLSLVV 12363

Query: 4574  LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
                      K+   A N+ G         VSLP   +    + K    PP+I+ P +  I
Sbjct: 12364 TGLKEGKKYKFRVAARNAVG---------VSLPREAEGVY-EAKEQLLPPKILMPEQITI 12413

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
              A G+ +     + GKP PT +W KG+  +  S +  + +      L I +   +D G Y
Sbjct: 12414 KA-GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYY 12472

Query: 4694  KCVAYNSAGRVTVAAKLKVTQPD 4716
                A NS+G  T   K+KV   D
Sbjct: 12473 SLTAENSSG--TDTQKIKVVVMD 12493



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 30/108 (27%), Positives = 54/108 (50%), Gaps = 3/108 (2%)

Query: 1028  RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT 1087
             +Y   +++   +   PR    ++ ++++  GQ+  F   V  QS  T  V+WY NG ++ 
Sbjct: 25862 KYEVLSQQPFTLDHAPRITLRMR-SHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQ 25918

Query: 1088  SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              +++I   +  G + L+I     +DSG Y  V  N  GEA   A++ V
Sbjct: 25919 ESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 5/134 (3%)

Query: 354   AVESPTESYVQDQRSQY--ITDTQQRE--TEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
             ++ S  ES+V+   S +  I++  Q E  T + ++   + + P+   +  D  + EGK+ 
Sbjct: 26790 SMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVL 26849

Query: 410   RFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHALMITNVTLSDSGVVTCVAR 468
                C  TG P PEVTW    R+I      +  + N      L+I +V   D G+ T    
Sbjct: 26850 TVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLG 26909

Query: 469   NKSGETAFQCRLNV 482
             N+ G  +    +++
Sbjct: 26910 NEFGSDSATVNIHI 26923



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 56/259 (21%), Positives = 98/259 (37%), Gaps = 12/259 (4%)

Query: 2887 VEQAEEARLAKGRRPSVPDTEYP-KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKI 2945
            V    EA++ +  R   P  E P  P  ++       ++EG+ + LE  +     P   +
Sbjct: 872  VLHGREAKVTETARVPAP-VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT--V 928

Query: 2946 EWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS 3005
             WY     +E    F++T   G   L + + +  DSG +TC A N+ G   TS  +    
Sbjct: 929  TWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988

Query: 3006 KDNLIERT---QHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD-IS 3061
             +   + T        TE    +++ +  +      +     G P     + K +V  + 
Sbjct: 989  SEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLV 1048

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTTDSG 3119
            EG    +   +   G+    + W  +G  +   +R +  Y    G   L I  T   D+G
Sbjct: 1049 EGGSVVFGCQV--GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1106

Query: 3120 TYSCRATNKWGQAEISVKL 3138
             Y+    NK G+   S  L
Sbjct: 1107 EYTIVVRNKHGETSASASL 1125



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 10/140 (7%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PV    +  LE +  G  A F C ++  + P++   WF  G++I    +          +
Sbjct: 4337 PVIKRKIEPLE-VALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKCSIRSSKYISS 4393

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV---AGHRNI--ILDTQHPNGLEKIRQL 2223
            L+IL T   D G Y CKA+N+ G    T TL V    G + +  +L  + P   E++  +
Sbjct: 4394 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEV--V 4451

Query: 2224 EAQGHSTRIEVEEPKISPPR 2243
                   R E EEPK+ P +
Sbjct: 4452 LKSVLRKRPEEEEPKVEPKK 4471



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 3/95 (3%)

Query: 3278  SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
             S E P    +++DVT  + G++A    ++V    PD+K  W+  GK+L    +Y+   D 
Sbjct: 24032 SGEAPGIRKEMKDVTTKL-GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDG 24088

Query: 3338  GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
                 L ++   +E+ G Y C+ATN++G   T + L
Sbjct: 24089 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 4/135 (2%)

Query: 1803  QSKASLQLESQHESALQKIQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLSEGQS 1861
             +  A   + S++ES    ++  + S R Y+        ++ APR   ++    ++  GQ+
Sbjct: 25835 ERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH-RVPCGQN 25893

Query: 1862  AHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
               +   ++    P   V+WY NG  LQ   +   +N  G   L+IL  + +DSG Y    
Sbjct: 25894 TRFILNVQS--KPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVC 25951

Query: 1922  INNLGQAVSSIRLNV 1936
              N  G+A     L+V
Sbjct: 25952 TNYKGEASDYATLDV 25966



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 2/107 (1%)

Query: 1696  KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
             KY+  S Q   +  AP  T+ M+  RV   Q   F   +     P   V+W  NGV ++ 
Sbjct: 25862 KYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQE 25919

Query: 1756  SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             S+++   +  G + L +   + +DSGTY     N  GEA   +TL V
Sbjct: 25920 SSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 36/147 (24%), Positives = 68/147 (46%), Gaps = 9/147 (6%)

Query: 3391  EGGLEKLQTLEDSMVR-RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
             EG L  +   ++ +V+ + D ++ +E   AP F +     +N+ EG+N  F   ++   +
Sbjct: 26607 EGILTCISKTKEGIVKCQYDLTLSKELSDAPAF-ISQPRSQNINEGQNVLFTCEIS--GE 26663

Query: 3450  PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
             P+ ++EW+ N   +   S            LEI      DSG+Y  +A N  G+   TAS
Sbjct: 26664 PSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATAS 26723

Query: 3510  MKV-----QGKRNIILESQLPKGMEGT 3531
             + V     +  R ++L +     ++G+
Sbjct: 26724 LMVLPLVEEPSREVVLRTSGDTSLQGS 26750



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 11/122 (9%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKT 2428
            +T Q P FTQPLQ++  + EG TA F+  +   G P  +V WFR+ ++I  S+   +  +
Sbjct: 1    MTTQAPTFTQPLQSV-VVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQIS 57

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ 2488
               G   +TI  V   + G Y  +A+N  G+              ++ ET  P  ++++Q
Sbjct: 58   FSDGRAKLTIPAVTKANSGRYSLKATNGSGQ------ATSTAELLVKAETAPPNFVQRLQ 111

Query: 2489 KL 2490
             +
Sbjct: 112  SM 113



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 5/98 (5%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDF 2697
            QAP FT  L+S   ++EG     EA +     P  ++ WF++G  ++T     ++ +F  
Sbjct: 4    QAPTFTQPLQSV-VVLEGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G   L+I ++   +SG Y+ KATN  G+A STA + ++
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/79 (32%), Positives = 40/79 (50%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G  A     +    KP IQW   G L+  + D++ + +G++  L+I  T  ED G +TC 
Sbjct: 3471 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 3530

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            A+   G+   SA L + SK
Sbjct: 3531 ASNDYGKTICSAYLKINSK 3549



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 14/128 (10%)

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866
            KI+E E G I +   + P++ TP      +     EE + V     +   ++    + WY
Sbjct: 4229 KIQEAEGGLIKE---DGPMIHTP------LVDTVSEEGDIVHLTTSITNAKE----VNWY 4275

Query: 3867 RNGKLLPSGHRYRTVYDMGFVSLDILYVYAED-SGEYICRAVNDFGEDFTKATISCKKLP 3925
               KL+PS  +++ + D    +L I  V  ED  GEY+C A+ND G+  T A ++  K  
Sbjct: 4276 FENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 4335

Query: 3926 DIILQNQV 3933
              +++ ++
Sbjct: 4336 APVIKRKI 4343



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L + V +EGD +H   ++  +++    + W+F NK +PS  ++K   D +  +L I    
Sbjct: 4249 LVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVN 4304

Query: 2840 EED-SGIYTCKATNSKGSATTSGSL 2863
             ED  G Y C+A N  G   TS  L
Sbjct: 4305 TEDHQGEYVCEALNDSGKTATSAKL 4329



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 25/81 (30%), Positives = 41/81 (50%)

Query: 498   STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
             S L V+ G  V L+A   G P P ++W+KDG  + P   +++       TL++      D
Sbjct: 12806 SLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKD 12865

Query: 558   AAWYQCTAQNVAGSTATRARL 578
             +  Y  TA+N +GS +   +L
Sbjct: 12866 SGDYTITAENSSGSKSATIKL 12886



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 46/142 (32%), Positives = 67/142 (47%), Gaps = 15/142 (10%)

Query: 4580  DSGKYE--CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP-LKDKI-VA 4635
             + GKYE    A N+AG     +E   ++   KD+ +       AP  +++P +KD + + 
Sbjct: 13843 EGGKYEFRIRAKNTAGAISAPSESTETI-ICKDEYE-------APTIVLDPTIKDGLTIK 13894

Query: 4636  EGQAIEFSC-KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694
              G  I  +   I+GKPLP   W K  K I+PS   Q++ T     L I  A  +D G+Y 
Sbjct: 13895 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 13954

Query: 4695  CVAYNSAGRVTVAAKLKVTQPD 4716
               A N  G  T    +KVT  D
Sbjct: 13955 ITATNPFG--TKVEHVKVTVLD 13974



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 25/89 (28%), Positives = 41/89 (46%)

Query: 490   APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
             AP   +    +  + GE   L+ + VG P P I W + G  +I + + ++ +DG   TL 
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094

Query: 550   IPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +   +  D   Y C A N  G   T ++L
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 2/94 (2%)

Query: 637   PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
             P FI   +S    EG  + F   I   G+P+ +IEW KN   I  SS  +        SL
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSL 26694

Query: 697   DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTP 730
             ++ + ++ DSG+YT +A +  G     A L V P
Sbjct: 26695 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLP 26728



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/148 (22%), Positives = 64/148 (43%), Gaps = 4/148 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L ++  ++G  +  +  V    +P +K  ++ +   + S   ++ + +    SL I
Sbjct: 106  FVQRLQSMTVRQGSQVRLQVRVTGIPNPVVK--FYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               Y EDSG Y+  ATNS G AT++  L   G++ +    +  +       + ++ + R+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV--PAKKTKTIVSTAQISESRQTRI 221

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923
             K              E +I  AA  QL
Sbjct: 222  EKKIEAHFDARSIATVEMVIDGAAGQQL 249



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 13/199 (6%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            +  ++Y+ + + + T  ++ I  + +  +F+   +D    E +   F   ++      V 
Sbjct: 5407 EDEAKYMFEAEDKHTSGKLII--EGIRLKFLTPLKDVTAKEKESAVFTVELS-HDNIRVK 5463

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
            WF ND+++    +   + +E   H++   ++++ D+  +   A   S E     +L V+E
Sbjct: 5464 WFKNDQRLHTTRSVS-MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEA----KLTVLE 5518

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
             +    P F  +       E + V+L         P + W KDG  I P+    I TDG 
Sbjct: 5519 GD----PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKTDGK 5573

Query: 545  ASTLDIPRAKASDAAWYQC 563
               L + +A  SD   Y C
Sbjct: 5574 KRMLILKKALKSDIGQYTC 5592



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/131 (23%), Positives = 60/131 (45%), Gaps = 2/131 (1%)

Query: 449   ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVREGEP 507
             +L++T +           ARN  G +  +    V E KEQ++ PK +     + ++ G+ 
Sbjct: 12360 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP-EQITIKAGKK 12418

Query: 508   VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
             + + A   G P P   W+K    ++ +  L +H    +S L I      D+ +Y  TA+N
Sbjct: 12419 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN 12478

Query: 568   VAGSTATRARL 578
              +G+   + ++
Sbjct: 12479 SSGTDTQKIKV 12489



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 25/94 (26%), Positives = 41/94 (43%)

Query: 4410  PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
             PP F        V   E  + +V F G P P + W+++N P+K +      +    S+L 
Sbjct: 15650 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15709

Query: 4470  IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
             I+    ED   +     N  G A  + N++V +K
Sbjct: 15710 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15743



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1976  EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
             E P   K +K+     G    L   +  V  P   ++WY  G+ + Q  ++K + D    
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH 24091

Query: 2036  ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
              L ++    ED G Y C ATN VGE  T+S + + A
Sbjct: 24092 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 35/144 (24%), Positives = 64/144 (44%), Gaps = 5/144 (3%)

Query: 1946  SQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIKNAEVTEGHPVHLEATLTPV 2004
             S++ES    ++  +   R    +    F ++  P+    +++  V  G        L   
Sbjct: 25844 SRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRF--ILNVQ 25901

Query: 2005  NDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
             + PT  V+WY NG  +Q+  +   T   G + L+IL  + +D+GTY    TN  GEA  +
Sbjct: 25902 SKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA--S 25959

Query: 2065  SSVKVDAKSGLYLDTLDEQRLKKI 2088
                 +D   G Y     ++R +++
Sbjct: 25960 DYATLDVTGGDYTTYASQRRDEEV 25983



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 5/114 (4%)

Query: 3674  KLEETLHKREEITIEDE--KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731
             K ++T  ++ E+  +      + PR T+ ++ +  VP G    F   V+    PT  + W
Sbjct: 25854 KTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH-RVPCGQNTRFILNVQ--SKPTAEVKW 25910

Query: 3732  FHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             +HNG      S++H  N  G + L+I   +  D+G Y    TN  G A+  A +
Sbjct: 25911 YHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATL 25964



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 1/118 (0%)

Query: 378  ETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            E +  ++ISE +A+   F    ++  + EG    F C+++G P P++ W+ + ++I+   
Sbjct: 1230 EEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE 1289

Query: 437  NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             +++   + G  +L I  V   D G+ T  A N  G      +L V     + AP ++
Sbjct: 1290 RYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1347



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 86/385 (22%), Positives = 153/385 (39%), Gaps = 39/385 (10%)

Query: 1558 LEDRSKYH------RTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKV 1611
            LED   Y+      RTD   +V   A    +  +N+EI EG++A F   +  +S  +  V
Sbjct: 6029 LEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEF---VCSISKESFPV 6085

Query: 1612 EWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA---VTSGIAI 1668
            +W  ++K L+SG ++    +     L +     +D GTY      A   A   V   + I
Sbjct: 6086 QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRI 6145

Query: 1669 VHSKKSIYLESQHEGALP-RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKD-IRVAENQ 1726
            V   K   ++ Q E      +N     +K+ R+   +E I  +  + +  KD +     +
Sbjct: 6146 VVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRN---EEAIFDSSKYIILQKDLVYTLRIR 6202

Query: 1727 AAHFEARL-IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPEDSGTYT 1784
             AH + +    V     R E +++     A+N +    D   V  L       + S T+ 
Sbjct: 6203 DAHLDDQANYNVSLTNHRGENVKS-----AANLIVEEEDLRIVEPLKDIETMEKKSVTFW 6257

Query: 1785 CRAINELGEAV----TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY-----QRRED 1835
            C+ +N L   +        +   ++ S +++        K     D   Y     Q +  
Sbjct: 6258 CK-VNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSV 6316

Query: 1836 VEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
             E+ + +AP  F+  L   T ++E   A + C++         V+WY NG+ ++ G +Y+
Sbjct: 6317 AELLIIEAPTEFVEHLEDQT-VTEFDDAVFSCQLSR---EKANVKWYRNGREIKEGKKYK 6372

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTC 1919
               D     L I     +D  EY C
Sbjct: 6373 FEKDGSIHRLIIKDCRLDDECEYAC 6397



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQKPRNSKL---QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             V PP++    +   +   + G   +    ++G P P ++W K+G  +    + EII+T N
Sbjct: 19287 VEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN 19346

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
             HT L V++  + D+G Y L  +N  G
Sbjct: 19347 HTLLTVKDCIRRDTGQYVLTLKNVAG 19372



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 32/118 (27%), Positives = 55/118 (46%), Gaps = 7/118 (5%)

Query: 1708  TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-FG 1766
             T  P+F   + +    E Q+  FE R+  +  P L+  W ++G P+     +  +H+   
Sbjct: 25295 TLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLD 25352

Query: 1767  YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ----SKASLQLESQHESALQK 1820
             Y AL+++   PED+G Y   A N  G     + L V+     K   + + +HE  +QK
Sbjct: 25353 YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQK 25410



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           +PP      KN    +G +   E  + G P+P V+W R+   +     + + +  Q+G  
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF--QSGIA 952

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            L+I++    D G +TC+A N+ G    S Y+
Sbjct: 953 RLMIREAFAEDSGRFTCSAVNEAGTVSTSCYL 984



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 8/116 (6%)

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
            + LE+    K    I ES  ++  F  R K+   ++EG  V F CK+        K+ W+
Sbjct: 1223 ELLEEDGEEKMAVDISESEAVESGFDLRIKNYR-ILEGMGVTFHCKMSGYPLP--KIAWY 1279

Query: 1482 KNGQPVTIGHRFRPIHDF---GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            K+G+ +  G R++   DF   G  +L I  ++ ED GIYT  A N+ G    S +L
Sbjct: 1280 KDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKL 1333



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 12/173 (6%)

Query: 3050 FTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLE 3109
            FT   +D+V   +  +A +E     T +  + ++W+ +G  +    + R      +  L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 3110 ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHF 3169
            IL   T+D+  YSC         + +VK       +G    F   +Q+IE + +  S   
Sbjct: 2187 ILTIDTSDAEDYSCVLVE-----DENVKTTAKLIVEGAVVEFVKELQDIE-VPESYSGEL 2240

Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            EC V P    +++ +WYHN   ++ + +    S  G   L +      D GEY
Sbjct: 2241 ECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2290



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 42/196 (21%), Positives = 85/196 (43%), Gaps = 7/196 (3%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
             ET E ++ SE    P  + +    D+T+  ++    +       ++T ++ + Q +    
Sbjct: 14457 ETTEPVKASEAPSPPDSLNIM---DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 14513

Query: 438   HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER- 496
                +    G   + + N+T  +      +A N +G +A +    VI KEQ + P+   R 
Sbjct: 14514 WTHITTVKGLECV-VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRG 14572

Query: 497   -FSTLNV-REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
              +  L + + G+ + +    +G P P +TW+K    +     +   T   ++ L+I    
Sbjct: 14573 IYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECV 14632

Query: 555   ASDAAWYQCTAQNVAG 570
              SD+  Y  TA+N+ G
Sbjct: 14633 RSDSGPYPLTARNIVG 14648



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 23/83 (27%), Positives = 37/83 (44%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P +  P     +  G+ ++    ++G+P P + W K  + +K +    +  TA    L I
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVT 4705
              E   +D G Y   A NSAG  T
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTAT 17897



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/132 (26%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 452   ITNVTLSDSGVVTCVARNKSGETAFQCRLN--VIEKEQVVAP--KF-VERFSTLNVREGE 506
             +T ++  D      +ARN  G  +   + +  ++ +++ V P  +F  E F  L ++ GE
Sbjct: 21418 VTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGE 21477

Query: 507   PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
              + + A   G P PR+TW KDGV I     + I    G+++L +  A       Y   A+
Sbjct: 21478 SLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEAK 21537

Query: 567   NVAGSTATRARL 578
             N +GS     ++
Sbjct: 21538 NASGSAKAEIKV 21549



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 70/294 (23%), Positives = 120/294 (40%), Gaps = 28/294 (9%)

Query: 4218  YDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEY 4277
             Y +  Q QR   E E     R V   Q + +++ EL   + KE     ++S K+ + +  
Sbjct: 25690 YRQPKQRQRIMAEREDEELLRPVTTTQHLSEYKSELD-FMSKE-----EKSRKKSRRQRE 25743

Query: 4278  YNKLQELENEQVIKESRLRESTHQYA--IPGDKVTSNTVAKSMAQRYE------DNLDQT 4329
               ++ E+E E  I +   RES+   +  +   +  S T  + M    E         ++ 
Sbjct: 25744 VTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEY 25803

Query: 4330  EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAK-QKQTQKEVVGDKEITRKITSTETT 4388
             E+ TE+R       +PR P P  S     E  +++ ++  + ++    E  +    T+ T
Sbjct: 25804 EDDTERRSPTPERTRPRSPSPVSS-----ERSLSRFERSARFDIFSRYESMKAALKTQKT 25858

Query: 4389  EIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN 4448
               E K    E + + P      P  T +M+  RV   +  RF +    +P   +KWY   
Sbjct: 25859 S-ERK---YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG 25914

Query: 4449  FPIKNSPDFQIHTFSTKSILI--IRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
               ++ S   +IH  +T  +L   I     +DS  + AV  N  G A   A L V
Sbjct: 25915 VELQESS--KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 3/105 (2%)

Query: 2242  PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
             PR    +R +  V  G+   F   V+    P   +++YHNG  LQ +++ H T   G ++
Sbjct: 25877 PRITLRMR-SHRVPCGQNTRFILNVQS--KPTAEVKWYHNGVELQESSKIHYTNTSGVLT 25933

Query: 2302  LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQR 2346
             L+I  C  +D+G Y     N  G  +   ++ VT        SQR
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQR 25978



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)

Query: 2788  GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
             G N  F  NV+    PT +++W+ N   L   ++   T+    ++L+I   + +DSG Y 
Sbjct: 25891 GQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 25948

Query: 2848  CKATNSKGSATTSGSLRCTG 2867
                TN KG A+   +L  TG
Sbjct: 25949 AVCTNYKGEASDYATLDVTG 25968



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/74 (32%), Positives = 38/74 (51%)

Query: 3312  PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
             P  +V+W++NG +L    +    +  G++ L+IL C+ ++SG Y  V TN  G  S  A 
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYAT 25963

Query: 3372  LKCTSKENLILDSQ 3385
             L  T  +     SQ
Sbjct: 25964 LDVTGGDYTTYASQ 25977



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/93 (30%), Positives = 44/93 (47%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I +K    ++  G  A+F  ++   P  R  WFK G+ +  S+K  I ++   ++L +
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4396

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
              TQ  D G YT  A N  G +  +  L V  P
Sbjct: 4397 LRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 4623 PEI---IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            PEI   ++ L    V  G  IE    + GKP P + W K D ++K  K   +     + T
Sbjct: 7191 PEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 7250

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            + I ++   D G Y   A N  GR T   ++ V
Sbjct: 7251 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 2/133 (1%)

Query: 213   TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKP 272
             T++S   D  +     +  ++  FR +  +  VG S  + +  +  +   + PPKI   P
Sbjct: 12351 TEYSVVKDLSLVVTGLKEGKKYKFRVA-ARNAVGVSLPREAEGVYEAKEQLLPPKILM-P 12408

Query: 273   RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
                 ++ G   + +  + G P P   W K    ++ S+   +    + + L +++  + D
Sbjct: 12409 EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKD 12468

Query: 333   SGHYTLLAENPNG 345
             SG+Y+L AEN +G
Sbjct: 12469 SGYYSLTAENSSG 12481



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 25/69 (36%), Positives = 37/69 (53%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L+ G   + +  +SG P P + W K+G+ L  + K EI      T L  +++ + DSG Y
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAY 15035

Query: 337   TLLAENPNG 345
             TL A NP G
Sbjct: 15036 TLTATNPGG 15044



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 82/394 (20%), Positives = 149/394 (37%), Gaps = 41/394 (10%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             R  V   G P P +KW + +  I+++    + +  T   L++  V   DS  +    EN 
Sbjct: 16464 RLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTS--LVLDNVNRYDSGKYTLTLENS 16521

Query: 4489  GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
              GT      + V +          PP        VN+   ++ +    +T   P+    L
Sbjct: 16522 SGTKSAFVTVRVLDTPS-------PP--------VNLKVTEITKDSVSITWEPPL----L 16562

Query: 4549  KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV--VSLP 4606
               G K++  I  K      +Y  ++   + ++S K + +    +   R  AE    + LP
Sbjct: 16563 DGGSKIKNYIVEKREATRKSYAAVVTNCH-KNSWKIDQLQEGCSYYFRVTAENEYGIGLP 16621

Query: 4607  ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
             A    P    K A  P    +   D +     ++ ++          +Q+    +     
Sbjct: 16622 AQTADP---IKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE 16678

Query: 4667  KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-------VTVAAKLKVTQPDQAD 4719
             K+ + +R      + I+     +E  ++ VA N  GR       V + AK  V +PD   
Sbjct: 16679 KWSECARVKSLQAV-ITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK- 16736

Query: 4720  NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
               PA +      V  GQ  + +  I+ + KPTI W ++G  + +T    +    +   L 
Sbjct: 16737 --PAFSSYS---VQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLS 16791

Query: 4780  IGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             I  T+++D G +        GQ   S ++V   K
Sbjct: 16792 IKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 16825



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F+ +++S TV +   VR + RV    +P   +++YR+G  + S   ++   +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPV--VKFYRDGAEIQSSLDFQISQEGDL 158

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             SL I   Y EDSG Y   A N  G   + A +
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 69   PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
            P PP   Q  +      G  A+F   + G P P +SW +++  L    K    ++ Q  +
Sbjct: 3190 PEPPQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQ--E 3247

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
             +LL+ +  P D   YTC A+N YG A  S  +  E
Sbjct: 3248 YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 13/135 (9%)

Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGP--------TKLSEGQSA 1862
            E Q ES     ++ E SS     E   V + +A   + + +GP        T   EG   
Sbjct: 4201 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIV 4260

Query: 1863 HYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED-SGEYTCKA 1921
            H    I    + N    WYF  K++ S  +++   D     L I  V  ED  GEY C+A
Sbjct: 4261 HLTTSITNAKEVN----WYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEA 4316

Query: 1922 INNLGQAVSSIRLNV 1936
            +N+ G+  +S +L V
Sbjct: 4317 LNDSGKTATSAKLTV 4331



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 6/131 (4%)

Query: 734  IERTSQHPETLQYI-QQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEA 792
            I++ +      +Y+ + L D  K      +       P   R ++ L E+  G  A F  
Sbjct: 4300 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPL-EVALGHLAKFTC 4358

Query: 793  QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKL 851
            ++   S P +R +W+K GR I  S +  SI +  Y+ SL I+  +  D G YT +A N+ 
Sbjct: 4359 EIQ--SAPNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4415

Query: 852  GEAISTASIRV 862
            G    TA++ V
Sbjct: 4416 GSVSCTATLTV 4426



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 74/400 (18%), Positives = 148/400 (37%), Gaps = 24/400 (6%)

Query: 4367 QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHE 4426
            + ++ VV DKE   ++ +     +   ++  E VV     P   P    +     V E E
Sbjct: 7848 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD--PDCKPTIDLETHDIIVIEGE 7905

Query: 4427 QARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAE 4486
            +    V F   P+P + W+++   +K S    +      + L + +    D+ ++    E
Sbjct: 7906 KLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLE 7965

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            N+ G+A  S N+ V         G+  P   + A ++  +S +L     +  G  PI ++
Sbjct: 7966 NKLGSATASINVKVI--------GLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPI-LH 8016

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            ++   ++        ++  +   +  + +  P     +   A+N  G         +  P
Sbjct: 8017 YVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGE---YIELKNP 8073

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
                 PK Q        E+  P  +   I  +    +   KI+G  +  +   KG++  K
Sbjct: 8074 VIAQDPK-QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIA--KGEERWK 8130

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
                  +      YT +  E   E +  ++  A N+AG    +     T+     + P +
Sbjct: 8131 RCNEHLVPILT--YTAKGLEEGKEYQ--FRVRAENAAGISEPSRATPPTKAVDPIDAPKV 8186

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGALIPE 4763
                 + V  G        I+    PTI W++ E  ++PE
Sbjct: 8187 ILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPE 8226



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 3/120 (2%)

Query: 4596  RCDAECVVSLPATKDKPKPQTKAANAPPEI---IEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
             R  AE +V L         + +    PP +   ++ ++  +V  G  + F   I G P+P
Sbjct: 10984 RVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVP 11043

Query: 4653  TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             T +W      IK  +++ +        L I      D G+Y+    N+AG  TVA  L V
Sbjct: 11044 TAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
             +  G+  R    V GRP P VTWF +  +I    N +I  N  G+ +L + + T    GV
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI-TNVLGSTSLFVRDATRDHRGV 21531

Query: 463   VTCVARNKSGETAFQCRLNVIEKE-QVVAP 491
              T  A+N SG    + ++ V +   +VV P
Sbjct: 21532 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21561



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 8/144 (5%)

Query: 375   QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
             +++ T  +I+ +   LA + +   +   V EG+  RF C   G P P VTW    + +  
Sbjct: 26050 EEKSTTRKIKTT---LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLST 26106

Query: 435   DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
                H++   +       I++V  SD G  + V  N  G+   +  L  I+K +V      
Sbjct: 26107 SARHQVTTTKY-KSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL-TIQKARVTEKAVT 26164

Query: 495   ERFSTLNVREGEPVVLNARAVGTP 518
                S   V+  EP V +  AV +P
Sbjct: 26165 ---SPPRVKSPEPRVKSPEAVKSP 26185



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E +PP F Q  ++    QG   + + ++ G P PVV + R  A +     + +    Q G
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQI---SQEG 156

Query: 128 DV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           D+ SLLI +  P D G Y+  A N  G A  +  +  +G
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 10/246 (4%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             + ++   G+PLP +   R+  P+K +  F     +    + +++    D+  +   A N 
Sbjct: 19998 KVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANS 20057

Query: 4489  GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
              GT K   N+VV +  R G     PP+  +   ++   S  L     K  G   +  Y L
Sbjct: 20058 SGTTKAFINIVVLD--RPG-----PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL 20110

Query: 4549  KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG-EARCDAECV-VSLP 4606
                ++    +  ++        + +++    +  ++   A N  G     D+ CV V LP
Sbjct: 20111 LK-RETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLP 20169

Query: 4607  ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
              T   P       N   E I     + V+ G +      +  K   ++ W K +KL+  +
Sbjct: 20170 YTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRT 20229

Query: 4667  KYFQMS 4672
              +F+++
Sbjct: 20230 THFKVT 20235



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 4/97 (4%)

Query: 2642  PIFTTHLKSYDKLV--EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
             PI     + +D L+   G+ + ++A V+ R  P  ++ WFK+GV +     ++ T   G 
Sbjct: 21459 PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVP--RVTWFKDGVEIEKRMNMEITNVLGS 21516

Query: 2700  VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              +L +     D  G+YT +A N  G A +   +K++D
Sbjct: 21517 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21553



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 36/69 (52%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G   + +  + G P PRVTWFK+G  +      EI      T+L VR+  +   G Y
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVY 21532

Query: 337   TLLAENPNG 345
             T+ A+N +G
Sbjct: 21533 TVEAKNASG 21541



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ GA  +  V +SG P P +TW K G  L  +++  I TT +++ L V    + D+G Y
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSKQGIDL--ASRAIIDTTESYSLLIVDKVNRYDAGKY 23018

Query: 337   TLLAENPNG 345
             T+ AEN +G
Sbjct: 23019 TIEAENQSG 23027



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 3830  PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
             P+   +++SH V   +  RF   V+ K  P   ++WY NG  L    +       G ++L
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTSGVLTL 25934

Query: 3890  DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             +IL  + +DSG Y     N  GE    AT+
Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEASDYATL 25964



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 2387  NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
             NI EGQ   F C +   G+P+ ++EWF+N   I  SS ++ +      S+ I +    D 
Sbjct: 26647 NINEGQNVLFTCEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 26704

Query: 2447  GVYMCRASNLLGE 2459
             G Y  +A N  G+
Sbjct: 26705 GKYTIKAKNFRGQ 26717



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 29/130 (22%), Positives = 62/130 (47%), Gaps = 4/130 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P F   ++ + V +      + R+  + +P   V++ R+G  I++S       +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPV--VKFYRDGAEIQSSLDFQISQEGDL 158

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L +    PEDSGTY+  A N +G A +++ L VQ +   ++ ++    +    Q+ +S
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--EVPAKKTKTIVSTAQISES 216

Query: 1828 SRYQRREDVE 1837
             + +  + +E
Sbjct: 217  RQTRIEKKIE 226



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 32/89 (35%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH-DFSYVSLD 2834
            F   + N    EG  + F C +  S  P  KI W+ + K +  G RY+         SL 
Sbjct: 1247 FDLRIKNYRILEGMGVTFHCKM--SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLR 1304

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I     ED GIYT  A+N KG+A  SG L
Sbjct: 1305 IPVVLPEDEGIYTAFASNIKGNAICSGKL 1333



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 48/232 (20%), Positives = 83/232 (35%), Gaps = 8/232 (3%)

Query: 4583  KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             +Y   A N AG  +C   C          P  Q +  N   + +     K   +G A   
Sbjct: 19161 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKIT 19220

Query: 4643  SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                +  + LP  +W K +       YF+++   ++        F  +  D       S G
Sbjct: 19221 GYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEF-RVFARNAADSVSEPSESTG 19279

Query: 4703  RVTVAAKLKVTQPDQADNLPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALI 4761
              + V  K  V  P    ++      RD++V + G+  +    I  +  P I W ++G  I
Sbjct: 19280 PIIV--KDDVEPPRVMMDVK----FRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19333

Query: 4762  PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              E    ++I   N+ +L + +    DTG +       AG    +    V  K
Sbjct: 19334 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 6/106 (5%)

Query: 3544  TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLI--PVNDSSMRVEWFHNGKPLL 3601
             T  ++  +  SG  P       D+      +A   C+++  P+ D    ++W+  GK L+
Sbjct: 24022 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD----IKWYRFGKELI 24077

Query: 3602  TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
                + K  +D     L +    Q D G+YTC ATN  GE   S KL
Sbjct: 24078 QSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/82 (32%), Positives = 35/82 (42%)

Query: 4514  PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
             P  TL  ++  V  GQ  R    V      +V W  NG ++Q   +       G  TL I
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936

Query: 4574  LEAYPQDSGKYECVAINSAGEA 4595
             L+ +  DSG Y  V  N  GEA
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKGEA 25958



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYVAL 1770
            F + +K+ R+ E     F  ++   G P  ++ W ++G  I+   R  +  + D G  +L
Sbjct: 1247 FDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQD-GRASL 1303

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
             +  V PED G YT  A N  G A+ S  L+V+  A L
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPL 1341



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 20/136 (14%)

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LDITHTYEEDSGIYTCKAT 2851
            F C ++ +  P ++ +WF   + +    +  S     Y+S L+I  T   D G YTCKA+
Sbjct: 4356 FTCEIQSA--PNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKAS 4412

Query: 2852 NSKGSATTSGSLRCT---GDKNI--YFDTQHPQGKAGL-----------EAVEQAEEARL 2895
            N  GS + + +L  T   G+K +      + P+ K  +           E   + E  +L
Sbjct: 4413 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4472

Query: 2896 AKGRRPSVPDTEYPKP 2911
             K ++P+VP+   PKP
Sbjct: 4473 EKVKKPAVPEPPPPKP 4488



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            I+  P +F+  ++  TV E +   F C++  +   K  ++WYRNG+ +  G +Y+   D 
Sbjct: 6321 IIEAPTEFVEHLEDQTVTEFDDAVFSCQLSRE---KANVKWYRNGREIKEGKKYKFEKDG 6377

Query: 3885 GFVSLDILYVYAEDSGEYIC 3904
                L I     +D  EY C
Sbjct: 6378 SIHRLIIKDCRLDDECEYAC 6397



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/91 (27%), Positives = 43/91 (47%)

Query: 481  NVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH 540
            NV+ K+    P        + V EGE + +       P P ++W KDG  +  +  L + 
Sbjct: 7880 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMK 7939

Query: 541  TDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             D  ++ L++P++  +DA  Y  T +N  GS
Sbjct: 7940 NDHISAHLEVPKSVRADAGIYTITLENKLGS 7970



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)

Query: 4512  VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
             + PS  L     ++ +G+ ++++  V G    ++ W+K+G+ ++   R  + EE  T T+
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV-EETATSTV 17871

Query: 4572  L-ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
             L I E    D GKY   A NSAG A  +   +V
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 4/110 (3%)

Query: 467   ARNKSG-ETAFQCRLNVIEKEQVVAPKF-VERFS--TLNVREGEPVVLNARAVGTPTPRI 522
             A N++G     +  L V+ KEQ+  P+  ++ F   T+ VR G  + ++    G P P++
Sbjct: 19952 AENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 20011

Query: 523   TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             T  +DGVP+               T+++  +  +DA  Y+ TA N +G+T
Sbjct: 20012 TLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTT 20061



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 12/139 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-- 2164
            Q P F   L S+  L EG  A FE  +     P   + WF +GQ I           F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSD 60

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
            G   L I      +SG Y  KATN  G+A +T  L V        +T  PN +++++ + 
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------ETAPPNFVQRLQSMT 114

Query: 2225 A-QGHSTRIEVEEPKISPP 2242
              QG   R++V    I  P
Sbjct: 115  VRQGSQVRLQVRVTGIPNP 133



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS--RFTSIFRFGYI 694
           P F  PL+SV  +EG    FE  I   G P  ++ W ++GQ I  S+       F  G  
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + ++   +SG Y+ +A + +G A + A L V
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 2/117 (1%)

Query: 377   RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
             RE E   E  E+ L P+ + + +   +  GK  R +  V G+P+P   W   + ++    
Sbjct: 12388 REAEGVYEAKEQLLPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS- 12445

Query: 437   NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
             +H  +     +  L+I +VT  DSG  +  A N SG    + ++ V++      P F
Sbjct: 12446 SHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12502



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 2780  LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
             + ++  K G+     C +     P +K  W+   K L    +YK + D    +L +    
Sbjct: 24042 MKDVTTKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEE 24099

Query: 2840  EEDSGIYTCKATNSKGSATTSGSL 2863
             +ED G+YTC ATN  G   TS  L
Sbjct: 24100 QEDEGVYTCIATNEVGEVETSSKL 24123



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P+F+++  NA   +G +  FE ++ G P P + W +   PL       +  +E     +L
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEI-IHEGLDYYAL 25356

Query: 132   LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
              I+   P D G Y  TA N  G   C  ++Q E
Sbjct: 25357 HIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 7/136 (5%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P   + I+  EV  GH       +     P +R +W+  GR + +  +          +L
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSL 4394

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG--LYLDTLDEQRLKKIQE--LEK 2093
            +IL     D G Y CKA+N  G    T+++ V    G       L E++ +  +E  L+ 
Sbjct: 4395 EILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKS 4454

Query: 2094 YERPKPIEEEQPGQRP 2109
              R +P EEE+P   P
Sbjct: 4455 VLRKRP-EEEEPKVEP 4469



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+ ++  +    A G  AKF  +++  P     W +    + E +K S+R ++    + +
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4396

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            L  Q+   D GEYTC A N+YG   C+
Sbjct: 4397 LRTQVV--DCGEYTCKASNEYGSVSCT 4421



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 9/119 (7%)

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            G  A F C+++    PN+R +++  G+ +  + +  I       SL+I      D GEY+
Sbjct: 4351 GHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 4408

Query: 2317 VKAINALGHCTSAISMTVTAKGS-----IISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             KA N  G  +   ++TVT  G       +   ++PE  E++  L+S    KRPE  EP
Sbjct: 4409 CKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEV-VLKSVLR-KRPEEEEP 4465



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 4/128 (3%)

Query: 233   EVSFRESITKRYVGESDV-QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
             E SFR S  +   G SD  Q+S  +      V PP          +  G D +  V   G
Sbjct: 15619 EYSFRVS-AQNEKGISDPRQLSVPVIAK-DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG 15676

Query: 292   NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG-CIVTS 350
              P P VTW K+   L  + +    +T N++ L +++  + D GHY +   N  G  I T 
Sbjct: 15677 RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETL 15736

Query: 351   GYLAVESP 358
               + ++ P
Sbjct: 15737 NVIVLDKP 15744



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             GQ + +E  +  R  P   I W K+G+ L    R+  T    L TLSI     DD G Y 
Sbjct: 16747 GQDLKMEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYG 16804

Query: 2717  CKATNLLGEAVSTASIKI 2734
                 N++G+   TASI+I
Sbjct: 16805 ITVANVVGQ--KTASIEI 16820



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 19/63 (30%), Positives = 32/63 (50%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G +   ++   G P+P ++W K+G  L  S       T N  TL ++N +K   G YT++
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140

Query: 340   AEN 342
              +N
Sbjct: 21141 LDN 21143



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ GA  +  +   G P P   W K    L  S + +I TT + +TL V N  ++D+G Y
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKY 21929

Query: 337   TLLAENPNG 345
             TL  EN +G
Sbjct: 21930 TLTVENNSG 21938



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             G+   L  Q+  R  P++K  W++ G  L    + K + D    TL++ +   +D G+YT
Sbjct: 24050 GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 2717  CKATNLLGEAVSTASIKIE 2735
             C ATN +GE  +++ + ++
Sbjct: 24108 CIATNEVGEVETSSKLLLQ 24126



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 3/81 (3%)

Query: 1057  EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD-FGYVALDIASVRAEDSGV 1115
             EGQS  FE RV      T+  +W  +G+ ++    I+  H+   Y AL I     ED+G 
Sbjct: 25311 EGQSVCFEIRVSGIPPPTL--KWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGY 25368

Query: 1116  YTVVARNAAGEAQLSASMTVE 1136
             Y V A N AG     A + VE
Sbjct: 25369 YRVTATNTAGSTSCQAHLQVE 25389



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 32/134 (23%), Positives = 65/134 (48%), Gaps = 4/134 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+  L+S+T  +G ++  + R+  + +P +K  + ++G  I++S  F         S
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
           L +     +DSG Y+  A ++ G A + A L V  +   E  ++  +T+    Q+ +  +
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV--QGEEEVPAKKTKTIVSTAQISESRQ 218

Query: 756 YQHQESIEEQTSQR 769
            + ++ IE     R
Sbjct: 219 TRIEKKIEAHFDAR 232



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 4/93 (4%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-DFGLVTL 2702
            F   +K+Y +++EG  V    ++     P  KI W+K+G  +  G R +  F   G  +L
Sbjct: 1247 FDLRIKNY-RILEGMGVTFHCKMSGYPLP--KIAWYKDGKRIKHGERYQMDFLQDGRASL 1303

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             I  +  +D GIYT  A+N+ G A+ +  + +E
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 16/156 (10%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMS 1641
            +KN  I EG    F  ++   S   L K+ WY + K +K G R+  +    G  +L I  
Sbjct: 1251 IKNYRILEGMGVTFHCKM---SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1307

Query: 1642 CLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE-SQHEGALPRLNQLEDTSKYQRH 1700
             LPED G YT  A N  G A+ SG         +Y+E +   GA   +  LE  S+ +  
Sbjct: 1308 VLPEDEGIYTAFASNIKGNAICSG--------KLYVEPAAPLGAPTYIPTLEPVSRIR-- 1357

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
            S     ++++P+   P +      + A    AR+ P
Sbjct: 1358 SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSP 1393



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 43/165 (26%), Positives = 64/165 (38%), Gaps = 9/165 (5%)

Query: 3351 NSGEYECVATNKLGRDSTKANLKCTSKEN---LILDSQLPRGMEGGLEKLQTLEDSMVRR 3407
            N+ E      NKL     K   KC   +N   L++D       +G     + L DS    
Sbjct: 4268 NAKEVNWYFENKLVPSDEK--FKCLQDQNTYTLVIDKVNTEDHQGEYV-CEALNDSGKTA 4324

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
                +   K  APV    +  +E +  G  A F   +     PN++ +W+  G+ +    
Sbjct: 4325 TSAKLTVVKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESD 4381

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            +           LEI  T   D GEY C+A N YG    TA++ V
Sbjct: 4382 KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 1/102 (0%)

Query: 245   VGESDVQISTEIDRSLGPVSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             VG+      T+       ++PP +    R+   ++ G       + SG P+P+V+WFK+ 
Sbjct: 10300 VGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDE 10359

Query: 304   QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               ++  ++  I TT     L     ++SDSG Y ++ EN  G
Sbjct: 10360 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 24/75 (32%), Positives = 36/75 (48%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             ++ R E    G+P P  KW +    +  S    +H   + SILII+ V  +DS  ++  A
Sbjct: 12417 KKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTA 12476

Query: 4486  ENRGGTAKCSANLVV 4500
             EN  GT      +VV
Sbjct: 12477 ENSSGTDTQKIKVVV 12491



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 1/80 (1%)

Query: 500   LNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             L ++ G+ +VLNA ++ G P P+ +W K G  I P+   +I +   +S L I  A   DA
Sbjct: 13891 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDA 13950

Query: 559   AWYQCTAQNVAGSTATRARL 578
               Y  TA N  G+     ++
Sbjct: 13951 GEYTITATNPFGTKVEHVKV 13970



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 79/385 (20%), Positives = 146/385 (37%), Gaps = 32/385 (8%)

Query: 644   KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI 703
             K +    GG +     I+  G PT +++W K    I  ++       F  + LD  ++N 
Sbjct: 16453 KIINIRAGGSLRLFVPIK--GRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNR 16508

Query: 704   QDSGEYTCRAVSATGVAETKAVLHV----TPRATIERTSQHPETLQYIQQ---LEDYSKY 756
              DSG+YT    +++G       + V    +P   ++ T    +++    +   L+  SK 
Sbjct: 16509 YDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKI 16568

Query: 757   QHQESIEEQTSQRPQFIRPLQD-------LGELQEGRNAHFEAQLTP---VSDPTMRVEW 806
             ++   +E++ + R  +   + +       + +LQEG + +F         +  P    + 
Sbjct: 16569 KNY-IVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADP 16627

Query: 807   YKDGRPITASSRITSIFNFGYVSLNIMHLRAE-DAGS----YTVRAVNKLGEAISTASIR 861
              K         +IT + +    S+++   + E D GS    Y V    K  E  S  + R
Sbjct: 16628 IKVAEVPQPPGKIT-VDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA-R 16685

Query: 862   VAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISI 921
             V +   V  +L   E+  +                       +   +P+ K P     S+
Sbjct: 16686 VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK-PAFSSYSV 16744

Query: 922   KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
             + G     E  +   G     + W KDG P++ ++RI    +     L+IK     D G 
Sbjct: 16745 QVGQDLKMEVPIS--GRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQ 16802

Query: 982   YTCRAYNAIGQATTSANLTIVTKKD 1006
             Y     N +GQ T S  +  + K D
Sbjct: 16803 YGITVANVVGQKTASIEIVTLDKPD 16827



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 3830  PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
             P    ++K  T +  E  +  C++  +  P   I+WYR GK L    +Y+   D    +L
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD--IKWYRFGKELIQSRKYKMSSDGRTHTL 24093

Query: 3890  DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              ++    ED G Y C A N+ GE  T + +  +  P
Sbjct: 24094 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATP 24129



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 4407  PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP-IKNSPDFQIHTF-ST 4464
             P + P F ++++   V     A    +  G P P++KWYR+    I +   ++I  F   
Sbjct: 24427 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24486

Query: 4465  KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
                LII  V  +D+ V+   A N+GG+   +A+L VE
Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 3430 ENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPE 3488
            + + +G +AHF  R+    DP  + EWY NG  ++   R   +     V  L I     E
Sbjct: 2041 QTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE 2098

Query: 3489 DSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            DS   + +A N  GE  + A + VQ K+ I    +L   +    D +A  E
Sbjct: 2099 DSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFE 2149



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/63 (34%), Positives = 34/63 (53%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   V W+KDG+ + AS R+T   +     L +      DAG YT+   NKLG A ++ +
Sbjct: 7917 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 7976

Query: 860  IRV 862
            ++V
Sbjct: 7977 VKV 7979



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 4622  PPEIIEPL--KDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             PPE+   +  +D I V  GQ I    ++ G+P P + W K  K++   K   + +     
Sbjct: 11408 PPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV 11467

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNL 4721
              L+I EA   D G Y   A NS+G    +A + V  +P    NL
Sbjct: 11468 ELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNL 11511



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 21/68 (30%), Positives = 38/68 (55%)

Query: 278   QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337
             +E ++ + ++ + G P P V+W K    L    +  + ++  +TTL V + QKSD+G YT
Sbjct: 13498 KENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYT 13557

Query: 338   LLAENPNG 345
             +  +N  G
Sbjct: 13558 ITLKNVAG 13565



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 6/88 (6%)

Query: 71    PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYN-EQTGDV 129
             PP F+ +F       G + K +    G PTP V+W +   PL    K + R N E T + 
Sbjct: 15650 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL----KQTTRVNAESTENN 15705

Query: 130   SLL-IKQIGPGDEGEYTCTARNQYGEAI 156
             SLL IK     D G Y     N  GEAI
Sbjct: 15706 SLLTIKDACREDVGHYVVKLTNSAGEAI 15733



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 5/103 (4%)

Query: 1302  REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP-IKTGHRFR 1360
             + D+ + QAP F   L N+     +N  L C++   G     V+W+  GK  I  G ++R
Sbjct: 24423 KSDVPI-QAPHFKEELRNLNVRYQSNATLVCKV--TGHPKPIVKWYRQGKEIIADGLKYR 24479

Query: 1361  -PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                ++  Y  L + SV  +D+ VY  +ATNQ G    + +L V
Sbjct: 24480 IQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/93 (34%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 488   VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHT-DGGA 545
             + AP F E    LNVR      L  +  G P P + W + G  II +  + RI    GG 
Sbjct: 24428 IQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGY 24487

Query: 546   STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               L I      DA  YQ  A N  GS +  A L
Sbjct: 24488 HQLIIASVTDDDATVYQVRATNQGGSVSGTASL 24520



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/94 (28%), Positives = 39/94 (41%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P I   ++   V  GQ   F   +  KP   V+WY     ++ S     + T+   TL I
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
              +   +D G Y+ V  N  G  +  A L VT  D
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGD 25970



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 3149  PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
             PR T  +++   +  GQ+  F   V     P  +++WYHNG  ++ S++I   +  G + 
Sbjct: 25877 PRITLRMRS-HRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 25933

Query: 3209  LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
             L+I      DSG Y     N  GE    AT++  G
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 25968



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/108 (21%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +++ +  T  P     L+++ +++G +   + R+  + +  +K  +Y +   ++S   F 
Sbjct: 94   ELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVK--FYRDGAEIQSSLDFQ 151

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             +      +L I    PEDSGTY+  A N++G A ++   +V  ++ +
Sbjct: 152  ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 11/139 (7%)

Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            +IE+  P +  P+    ++  T V +G  AHF  +V  V  P+   E+Y NG  ++ + R
Sbjct: 2022 KIELS-PSMEAPKIFERIQSQT-VGQGSDAHFRVRV--VGKPDPECEWYKNGVKIERSDR 2077

Query: 2291 FHITFDFGYV-SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG 2349
             +  +    V  L I+    ED+    VKAIN  G  +S   + V AK  I    +  + 
Sbjct: 2078 IYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDV 2137

Query: 2350 LEKIR------ELESAEPF 2362
            + K +      E E++EPF
Sbjct: 2138 VAKEKDTMATFECETSEPF 2156



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            V   KI +KP++    E A   F+V +S +  P V WF     +  S+KH +++      
Sbjct: 2746 VETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHK 2804

Query: 323  LRVRNTQKSDSGHYT 337
            L ++N   SD+G YT
Sbjct: 2805 LMLQNISPSDAGEYT 2819



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 2/125 (1%)

Query: 1278 DTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPV 1337
            +T++ Q     + L D+ +     +  +    AP   R +  +E   G      C +Q  
Sbjct: 4304 NTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA 4363

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             +  +R +WF  G+ I    +          +L++L     D G YTC+A+N+ G    +
Sbjct: 4364 PN--VRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT 4421

Query: 1398 CALRV 1402
              L V
Sbjct: 4422 ATLTV 4426



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/130 (30%), Positives = 58/130 (44%), Gaps = 9/130 (6%)

Query: 4583  KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             K+  +A+N+AGE+  D   V      KD+ +P     +A        +++ +  G  +  
Sbjct: 10689 KFRVLAVNAAGES--DPAHVPEPVLVKDRLEPPELILDA-----NMAREQHIKVGDTLRL 10741

Query: 4643  SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
             S  I G P P V W K D+   P+K  ++  T     L I  A  ED G Y     N AG
Sbjct: 10742 SAIIKGVPFPKVTWKKEDR-DAPTK-ARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAG 10799

Query: 4703  RVTVAAKLKV 4712
               TV+ K+ V
Sbjct: 10800 SKTVSVKVLV 10809



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 4495  SANLVVEEKRRQGRGGIV------PPSFTL--TAQNV-NVTSGQLVRLDTKVTGTKPIDV 4545
             +AN+V E + R+    ++      PP   L  T ++V  V  GQ +R+  +V G    D+
Sbjct: 11384 AANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDI 11443

Query: 4546  YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
              W K GK +  + R  ++++     L I EA   D GKY   A NS+G A+  A
Sbjct: 11444 TWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSA 11497



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 22/63 (34%), Positives = 32/63 (50%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G + + ++ + G P+P VTW K  Q L  + +    TT   T L +    +SDSG Y L 
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642

Query: 340   AEN 342
             A N
Sbjct: 14643 ARN 14645



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P++        V  GQ ++    I G+P PT+ W K    +K +    ++ + D  TL I
Sbjct: 16733 PDVKPAFSSYSVQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16792

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVTVAAKL-KVTQPD 4716
              E   +D G Y     N  G+ T + ++  + +PD
Sbjct: 16793 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD 16827



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 50/213 (23%), Positives = 83/213 (38%), Gaps = 10/213 (4%)

Query: 797   VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAE-DAGS----YTVRAVNKL 851
             V  P   V+  K   P +   ++T + +    S ++M  + E D GS    Y V    K 
Sbjct: 17700 VGVPVETVDAVKAAEPPSPPGKVT-LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKG 17758

Query: 852   GEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEF 911
              E  S  +      + VT  L   ++ ++  K                    + T +P  
Sbjct: 17759 TEKWSIVAESKVCNAVVTG-LSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSL 17817

Query: 912   KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTI 971
             K P  +  SI+ G     E  +  IG     + W+KDG P++ ++R+          L I
Sbjct: 17818 KLPF-NTYSIQAGEDLKIE--IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874

Query: 972   KSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
             K     D G YT  A N+ G AT + ++ ++ K
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 482   VIEKEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
             +I K+ V  P+    V+    + V+ GE + +NA   G P P I+W KDG+ I       
Sbjct: 19281 IIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTE 19340

Query: 539   IHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             I +    + L +      D   Y  T +NVAG+
Sbjct: 19341 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGT 19373



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 785   GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
             G+N  F   L   S PT  V+WY +G  +  SS+I      G ++L I+    +D+G+Y 
Sbjct: 25891 GQNTRFI--LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 25948

Query: 845   VRAVNKLGEAISTASIRVAARSTVT 869
                 N  GEA   A++ V      T
Sbjct: 25949 AVCTNYKGEASDYATLDVTGGDYTT 25973



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/61 (37%), Positives = 31/61 (50%)

Query: 3591  VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             V+W+HNG  L   S++   N  G + LEI   +  D+G Y    TN  GEA+    L V 
Sbjct: 25908 VKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 25967

Query: 3651  G 3651
             G
Sbjct: 25968 G 25968



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 20/51 (39%), Positives = 30/51 (58%)

Query: 3082  IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
             ++W++NG  ++ S +I      G++ LEIL   T DSGTY    TN  G+A
Sbjct: 25908 VKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA 25958



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGY 2299
            P F   L+    V EG TA FE  +     P   + ++ +G+ + ++      I+F  G 
Sbjct: 6    PTFTQPLQSVV-VLEGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L I      ++G YS+KA N  G  TS   + V A+ +  +  QR + +   +  +  
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 2360 EPFKRPEIPEPVTR 2373
               +   IP PV +
Sbjct: 123  LQVRVTGIPNPVVK 136



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F     + +  +G N +F+ K+ G P P   W      +V    + +   E  G  SL
Sbjct: 1411 PVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED-GTQSL 1469

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            +I    P D GE+T  A+N+ G +  SV +  E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1502



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 8/127 (6%)

Query: 619  ERARPYIPPGEEDRVYPPPQFIVP-----LKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            E  +  IP  + D++   P    P     ++S T  +G   HF  R+  VG P  + EW 
Sbjct: 2009 EEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRV--VGKPDPECEWY 2066

Query: 674  KNGQSIEASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            KNG  IE S R    +       L +  +  +DS     +A++  G   + A L V  + 
Sbjct: 2067 KNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126

Query: 733  TIERTSQ 739
             I  T +
Sbjct: 2127 LITFTQE 2133



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/130 (22%), Positives = 57/130 (43%), Gaps = 4/130 (3%)

Query: 3793 IVLESQLPQGMSGEKIKEL--ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850
            +V++    +   GE + E   + G+ + + K   +    P    +I+   V      +F 
Sbjct: 4298 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFT 4357

Query: 3851 CRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910
            C ++    P +R +W++ G+ +    +          SL+IL     D GEY C+A N++
Sbjct: 4358 CEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4415

Query: 3911 GEDFTKATIS 3920
            G     AT++
Sbjct: 4416 GSVSCTATLT 4425



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 47/203 (23%), Positives = 85/203 (41%), Gaps = 17/203 (8%)

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            + +  G  PI  Y ++  +  +PD          T + L+         ++   A+N  G
Sbjct: 8820 EPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIG 8879

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLP 4652
            E+  +    +++    D+  P  K        +    D I V  G+ +     + G P+P
Sbjct: 8880 ES--EPSLPLNVVIQDDEVPPTIKLR------LSVRGDTIKVKAGEPVHIPADVTGLPMP 8931

Query: 4653 TVQWYKGDKLI-KPSKYFQ-----MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             ++W K + +I KP+   Q     +SR+  +  L I +A  ED+G Y   A N  G V  
Sbjct: 8932 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 8991

Query: 4707 AAKLKV-TQPDQADNLPALTPLR 4728
               ++V  +P    NL A+T ++
Sbjct: 8992 NVHVEVYDRPSPPRNL-AVTDIK 9013



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/130 (25%), Positives = 63/130 (48%), Gaps = 7/130 (5%)

Query: 4677  EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK--VTQPDQADNLPALT---PLRD-I 4730
             E    +S    +   +++ +A N+AG ++  +     +T  D+ + LP ++     RD I
Sbjct: 17080 ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVE-LPRISMDPKFRDTI 17138

Query: 4731  VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             VV  G+  + +  +  K  PTI+WLR    I E+   ++ +    A+L++ +    D G 
Sbjct: 17139 VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 17198

Query: 4791  FTCRATTAAG 4800
             +  RA+  AG
Sbjct: 17199 YILRASNVAG 17208



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 21/78 (26%), Positives = 39/78 (50%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  + E+   G P P I W ++  P+K +    +   +T ++L I++   +D   +   A
Sbjct: 17830 EDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTA 17889

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N  GTA  + +++V EK
Sbjct: 17890 TNSAGTATENLSVIVLEK 17907



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G+D      + G P P++ W K  + L    K  +  T    T  ++   +SDSG Y
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKY 22621

Query: 337   TLLAENPNGCIVTSGYLAV-ESP 358
             TL  +N +G    S  + V +SP
Sbjct: 22622 TLTVKNASGTKAVSVMVKVLDSP 22644



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +++G   +  + + G P P   W K GQ +  S +  I T+  HT L ++   + DSG Y
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTY 23708

Query: 337   TLLAENPNG 345
              L+ EN  G
Sbjct: 23709 DLVLENKCG 23717



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P   +  K+     G  A+   ++ G P P + W R    L++  KY M  + +T  +++
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095

Query: 132   LIKQIGPGDEGEYTCTARNQYGE 154
             + ++    DEG YTC A N+ GE
Sbjct: 24096 MTEE--QEDEGVYTCIATNEVGE 24116



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 2/69 (2%)

Query: 2391  GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
             G+ A   C++  VG P   ++W+R  K +  S +   + D    ++T+     EDEGVY 
Sbjct: 24050 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 2451  CRASNLLGE 2459
             C A+N +GE
Sbjct: 24108 CIATNEVGE 24116



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 3/68 (4%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH-EIITTHNHTTLRVRN-TQKSDSGHYT 337
             G     ++  SG P P +TW K GQ LI++N H ++I T + T+L   N  ++ D+G Y 
Sbjct: 24545 GEVVSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYV 24603

Query: 338   LLAENPNG 345
             + A+N  G
Sbjct: 24604 VCAKNRFG 24611



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 3/134 (2%)

Query: 266   PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
             P+I  + R+ ++  G + +F + +   P   V W+ NG  L  S+K     T    TL +
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936

Query: 326   RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
              +    DSG Y  +  N  G    S Y  ++     Y     SQ   +   R     +  
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKG--EASDYATLDVTGGDYT-TYASQRRDEEVPRSVFPELTR 25993

Query: 386   SEKALAPQFVKVCQ 399
             +E    P F K  +
Sbjct: 25994 TEAYAVPSFKKTSE 26007



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/100 (25%), Positives = 51/100 (51%), Gaps = 3/100 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F+ ++Q +T + +G     + R+  + +P +K  ++ +G ++     ++   +  + 
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPNPVVK--FYRDGAEIQSSLDFQISQEGDLY 159

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             L I   Y E+SG Y   ATN +GR ++ A L    +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 1/115 (0%)

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            ++++   P  V     + V EGE      R  G P P++ W  +G  I  +   R+  DG
Sbjct: 1788 DQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRP 598
                LDI   K+ D    + TA+N  G    + +L            +R   PRP
Sbjct: 1848 -IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRP 1901



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 18/168 (10%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            KD+  +    +A +E S+      ++ ++WF+    I+ S + R V    +  L +    
Sbjct: 2756 KDVTALENATVA-FEVSV---SHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNIS 2811

Query: 3115 TTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174
             +D+G Y+       GQ      LEC  K   +    T  ++NIE + + ++A FEC V 
Sbjct: 2812 PSDAGEYTAVV----GQ------LECKAKLFVETLHITKTMKNIE-VPETKTASFECEVS 2860

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
              + P M   W  NG  +  S + K V       L I  T   DS EY
Sbjct: 2861 HFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEY 2905



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 65/284 (22%), Positives = 106/284 (37%), Gaps = 41/284 (14%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
            G+ A F+  +S +     TW K+G  +  S KH  I       L + + Q SD+G YT  
Sbjct: 4636 GSSAIFECLVSPSTAI-TTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT-- 4692

Query: 340  AENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ 399
                  C++  G     S  +  V++   +++     +  EE + + +        ++ +
Sbjct: 4693 ------CVLRLGNKEKTSTAKLVVEELPVRFV-----KTLEEEVTVVKGQPLYLSCELNK 4741

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +RDV   K  +      GR  P V   +                     AL I +   +D
Sbjct: 4742 ERDVVWRKDGKIVVEKPGRIVPGVIGLMR--------------------ALTINDADDTD 4781

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519
            +G  T    N +      C + V+E   V+    V+     +V+     +  A  +   T
Sbjct: 4782 AGTYTVTVENANNLECSSC-VKVVE---VIRDWLVKPIRDQHVKPKGTAIF-ACDIAKDT 4836

Query: 520  PRITWQK--DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            P I W K  D +P  PN +  I  DG    L I  A   D A Y
Sbjct: 4837 PNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY 4880



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 3/97 (3%)

Query: 485   KEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             +E++V P     V+    L V+ G  V   A   G P P   W  DG  I  +    + T
Sbjct: 11005 QEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVET 11064

Query: 542   DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             D  +S L I      D   YQ T  N AGS      L
Sbjct: 11065 DNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHL 11101



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 2648  LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             +KS   +  G +V L+A V  +  P   + W K+G  L     +K      L TL + S+
Sbjct: 12804 MKSLLTVKAGTNVCLDATVFGKPMPT--VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSV 12861

Query: 2708  RNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
                DSG YT  A N  G   +T  +K+ D+
Sbjct: 12862 NRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/69 (31%), Positives = 34/69 (49%)

Query: 936   IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             IG  T  V W KD  P++ ++R+          LTIK     D GHY  +  N+ G+A  
Sbjct: 15675 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 15734

Query: 996   SANLTIVTK 1004
             + N+ ++ K
Sbjct: 15735 TLNVIVLDK 15743



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 1707  ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
             +T  P   +P     +   +    E  +I  G P+  + W+++G P++ + R+       
Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVI--GRPRPNISWVKDGEPLKQTTRVNVEETAT 17868

Query: 1767  YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                L++K  N +D G YT  A N  G A  + ++ V  K
Sbjct: 17869 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/84 (29%), Positives = 38/84 (45%)

Query: 4623  PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             P +  P     V   + ++      G+P  TV W K  + +K +    +S +    +L I
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 18957

Query: 4683  SEAFPEDEGDYKCVAYNSAGRVTV 4706
              EA  ED G Y+    NSAG +TV
Sbjct: 18958 KEASKEDVGTYELCVSNSAGSITV 18981



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 21/70 (30%), Positives = 34/70 (48%)

Query: 4637  GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
             G  +       GKP P++ W K    +K S++ + S+T ++ TL I  A  E  G Y  +
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140

Query: 4697  AYNSAGRVTV 4706
               N+  R+ V
Sbjct: 21141 LDNAVCRIAV 21150



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 3/89 (3%)

Query: 3144  SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             + G+ P     ++++   K G++A   C +V    PD+K  WY  G+ +  S + K  SD
Sbjct: 24031 TSGEAPGIRKEMKDVT-TKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSD 24087

Query: 3204  FGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                  L +   +  D G Y C A N+ GE
Sbjct: 24088 GRTHTLTVMTEEQEDEGVYTCIATNEVGE 24116



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 2/80 (2%)

Query: 3435  GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
             G+N  F   L     P  +V+WY NG  L+  S+       G + LEI   + +DSG Y 
Sbjct: 25891 GQNTRFI--LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 25948

Query: 3495  CRAYNNYGEAVTTASMKVQG 3514
                 N  GEA   A++ V G
Sbjct: 25949 AVCTNYKGEASDYATLDVTG 25968



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDF--G 3613
            P FT     +++ E S+A FE  +   PV +    V WF +G+ + T +       F  G
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQISFSDG 61

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
               L I  V + ++G Y+ KATN  G+AT + +L VK
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 3/153 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T E +V+   A  PP FV    ++TV +G   R   RVTG P P V +  +G  I +   
Sbjct: 92   TAELLVKAETA--PPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLD 149

Query: 4157 YKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
            ++++ +G +Y   I +    D+G   V              L V    +      K    
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVID 4248
                  ++  R E ++E  F+ R +   + VID
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVID 242



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVS 130
            P+F +  KN    +G   + + +  GNP P + W  K + ++  +KY  +R     G+ +
Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL-KNSDIIVPHKYPKIRIEGTKGEAA 1568

Query: 131  LLIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPE 164
            L I      D   YT TA N+ G     C V ++ E
Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 80/392 (20%), Positives = 151/392 (38%), Gaps = 29/392 (7%)

Query: 910  EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
            EF  P++DQ +++EG  A  E     +     +V+W K+G  +  S +     +     L
Sbjct: 5789 EFTKPLEDQ-TVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKL 5844

Query: 970  TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRY 1029
             I   T  D   YTC A +      TS NL +V       E   P    +++  E A   
Sbjct: 5845 VIHDCTPEDIKTYTCDAKD----FKTSCNLNVVPPH---VEFLRPLTDLQVREKEMARFE 5897

Query: 1030 SKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSA 1089
             + + E  K+          KG    +  + A     V  +  L    E+    +   ++
Sbjct: 5898 CELSRENAKVKWFKDGAEIKKGKKYDIISKGA-VRILVINKCLLDDEAEYSCEVRTARTS 5956

Query: 1090 NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL----SASMTVET-RSSIDTS 1144
              +    +      ++A++   ++    +V   +   A++         +ET R  I T 
Sbjct: 5957 GMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTE 6016

Query: 1145 SIHRGLYEKTRHIEESKFVE---PMYQIEEISKSKPVFVQPLSNPP--PVSEGKNIHLEC 1199
               R L  +  H+E++       P  + +   K   +  + +S P    + EG+     C
Sbjct: 6017 GRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVC 6076

Query: 1200 RLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLG 1259
             +     P   V+W  + +++  G ++    D     L +  AT  D G Y V     +G
Sbjct: 6077 SISKESFP---VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VG 6129

Query: 1260 SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL 1291
            +A  +A + VIE+  IV   ++ +  EQ +++
Sbjct: 6130 AARAAAHLTVIEKLRIVVPLKDTRVKEQQEVV 6161



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 6/120 (5%)

Query: 378   ETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
             E  + IE+ ++ ++P        RD   V  G + R    V+G+P P VTW +N+R +  
Sbjct: 10011 EVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQ 10070

Query: 435   DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             +   +     S   +++I N   S  GV + +A+N++GE      ++V++    V   F+
Sbjct: 10071 EATIETTAISS---SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 10127



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 24/69 (34%), Positives = 33/69 (47%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L+ G   +  V + G P P++TW K    L +    +I +T   T LR  N  K D+G Y
Sbjct: 13208 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13267

Query: 337   TLLAENPNG 345
              L  EN  G
Sbjct: 13268 ILTLENSCG 13276



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 35/113 (30%), Positives = 51/113 (45%), Gaps = 5/113 (4%)

Query: 235   SFRES-ITKRYVGESDVQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGN 292
             +FR S I    VGE  V    EI +R + P      A+  R   ++ G   +  V + G 
Sbjct: 14248 NFRISAINDAGVGEPAVIPDVEIVEREMAPDFELD-AELRRTLVVRAGLSIRIFVPIKGR 14306

Query: 293   PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             P P VTW K+   L   N+  I  T + T L +    + D+G + +  ENP G
Sbjct: 14307 PAPEVTWTKDNINL--KNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 14357



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/66 (33%), Positives = 32/66 (48%)

Query: 797   VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
             +  PT  V W+KD  P+  ++R+ +        L I     ED G Y V+  N  GEAI 
Sbjct: 15675 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 15734

Query: 857   TASIRV 862
             T ++ V
Sbjct: 15735 TLNVIV 15740



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 21/66 (31%), Positives = 33/66 (50%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G D Q  +   G P P VTW K+ + L +  ++ I  T + + L +    ++D+G Y L 
Sbjct: 20789 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 20848

Query: 340   AENPNG 345
              EN  G
Sbjct: 20849 IENGVG 20854



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 2122  KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
             K G+ A   C++  +  P   I W+  G+++    +Y+ + D     L ++    ED G 
Sbjct: 24048 KLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 24105

Query: 2182  YMCKATNKLGEAVNTCTL 2199
             Y C ATN++GE   +  L
Sbjct: 24106 YTCIATNEVGEVETSSKL 24123



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-- 3475
            +AP FT PL ++  L EG  A FEA ++    P  +V W+ +G+ +   +       F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            G   L I      +SG Y  +A N  G+A +TA + V+ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GF 3752
            P FT  ++ ++ V EG    F+  +   G P   + WF +G+  +T +       F  G 
Sbjct: 6    PTFTQPLQ-SVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L I  +   ++G Y+ +ATN  G AT+TA++   A+
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            L D+ K    +    V   APV    ++ + VA    A F   +     P +R +W + G
Sbjct: 4317 LNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAG 4374

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
              I  S++ +        +L +      D G YTC+A NE G    ++TL V
Sbjct: 4375 REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             V  G+ I +  R++  G P   + W   G+ +    R     D   V L I  A  AD G
Sbjct: 11423 VRVGQTIRILARVK--GRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480

Query: 1249  EYTVRAVNHLGSAHTSAIVRVIER 1272
             +Y + A N  G A  SAIV V++R
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVLDR 11504



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 6/101 (5%)

Query: 2640  QAPIFTTHLKSYDKLV--EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-D 2696
             +AP     +K  D ++   G+   LEA V  R  P +  EW K+G  L   A+L+    D
Sbjct: 14960 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTM--EWSKDGKELEGTAKLEIKIAD 15017

Query: 2697  FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             F    ++ +S R D SG YT  ATN  G A    ++K+ DR
Sbjct: 15018 FSTNLVNKDSTRRD-SGAYTLTATNPGGFAKHIFNVKVLDR 15057



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 6/91 (6%)

Query: 1576  QAPICTTSLKNVEIKEGQRAHFERRLI--PVSDATLKVEWYHNNKPLKSGSRFTETNNFG 1633
             +AP     +K+V  K G+ A    +++  P+ D    ++WY   K L    ++  +++  
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD----IKWYRFGKELIQSRKYKMSSDGR 24089

Query: 1634  FVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                L +M+   ED G YTC A N +GE  TS
Sbjct: 24090 THTLTVMTEEQEDEGVYTCIATNEVGEVETS 24120



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 4/122 (3%)

Query: 246   GESD-VQISTEID-RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             GES+  +IS  I  +S  P+  P   ++ RN  ++  ++A    +++G+P+P V W++ G
Sbjct: 24409 GESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQG 24468

Query: 304   QRLI-NSNKHEIIT-THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTES 361
             + +I +  K+ I      +  L + +    D+  Y + A N  G +  +  L VE P + 
Sbjct: 24469 KEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKI 24528

Query: 362   YV 363
             ++
Sbjct: 24529 HL 24530



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 636   PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSI---EASSRFTSIFRFG 692
             PP+F +PL + TA  G  + F   I    +P   + W K+GQ I   +   ++T     G
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 25249

Query: 693   YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
                L + S+   D  EYT  A +  G    KA L VT
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 25286



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 71    PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR---KKAPLVECNKYSMRYNEQTG 127
             PP F     N     G N +F   +  +P P V+W +   K  P     KY+  +    G
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT--FESDKG 25249

Query: 128   DVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
                L I  +   D+ EYT  ARN+YGE  C
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSC 25279



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 12/172 (6%)

Query: 3704  NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGFIALDIDYIYA 3762
             N +  EG  V F+ RV  +  PT++  W  +G+P + G  +  +++   + AL I     
Sbjct: 25306 NAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLP 25363

Query: 3763  RDAGEYTCRATNKWGSATTTAKITCS----AKRDIVLESQLPQGMSGEKIKELERGRISD 3818
              D G Y   ATN  GS +  A +        K++   + +  + +  +  K L    I  
Sbjct: 25364 EDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILS 25423

Query: 3819  APKEEPIVSTPPKFITQ--IKSHTVEESEGVRFECRV---EPKEDPKLRIEW 3865
               +  P+     + + +  +       ++ V+ E R+   E KE+ KLR+ +
Sbjct: 25424 GTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLRMPY 25475



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 48/245 (19%), Positives = 84/245 (34%), Gaps = 19/245 (7%)

Query: 522   ITWQKDGVPIIPNPELRIHTDG-GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             +TW KDG  +  N   + H    G   L I     SD   Y C      G++ T  +   
Sbjct: 26252 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 26311

Query: 581   XXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFI 640
                       K +H  + +K+                  +  P  P    + +   P  +
Sbjct: 26312 QAF-------KSIH-EKVSKISETKKSDQKTTESTV-TRKTEPKAP----EPISSKPVIV 26358

Query: 641   VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLS 700
               L+  T        F   ++  G+P     W K+G++I    ++      G   L++  
Sbjct: 26359 TGLQDTTVSSDSVAKFA--VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 26416

Query: 701   LNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQE 760
              +  DSG YTC   ++ G   +   L +     I+ T     + Q   ++    K   QE
Sbjct: 26417 TDTSDSGLYTCTVKNSAGSVSSSCKLTI---KAIKDTEAQKVSTQKTSEITPQKKAVVQE 26473

Query: 761   SIEEQ 765
              I ++
Sbjct: 26474 EISQK 26478



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP FV ++QS T     + ++   Q+   G PN  V+++ +G  +     F    +    
Sbjct: 103  PPNFVQRLQSMTV---RQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP-KHMKSIEKIREM 4090
            ++     YPEDSG Y   ATN  G   + A +   G      + ++P K  K+I    ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EEEVPAKKTKTIVSTAQI 213

Query: 4091 EASWQVTPEQVVE 4103
              S Q   E+ +E
Sbjct: 214  SESRQTRIEKKIE 226



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 87/362 (24%), Positives = 150/362 (41%), Gaps = 45/362 (12%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            +P  + +  S + V EG  V  E K   V+  +++  W K+GQ V    R   + D    
Sbjct: 2308 RPIAILQGLSDQKVCEGDIVQLEVK---VSLESVEGVWMKDGQEVQPSDRVHIVIDKQSH 2364

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L I D+  ED+G Y+   +  +G    S R++  S  D++        L+ + V+E   
Sbjct: 2365 MLLIEDMTKEDAGNYSF-TIPALGLS-TSGRVSVYSV-DVITP------LKDVNVIEG-- 2413

Query: 1563 KYHRTDMVDEVTTQAPICTTS---LKNVEIKEGQRAHFERRLIPVSDATLKVEWYH--NN 1617
                T  V E     P  T+    L + +IK   R    + ++  +   L +   H  + 
Sbjct: 2414 ----TKAVLECKVSVPDVTSVKWYLNDEQIKPDDRV---QAIVKGTKQRLVINRTHASDE 2466

Query: 1618 KPLKSGSRFTETN-NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS----- 1671
             P K      ETN N     + I+  L + + T T   +  + E   SGI ++ +     
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV-ELSHSGIDVLWNFKDKE 2525

Query: 1672 -KKSIYLESQHEGALPRLNQL----EDTSKYQRHSAQD----EVITQAPVFTMPMKDIRV 1722
             K S   + +  G + +L  L    +D  KY  ++ ++    ++       + P+ D  V
Sbjct: 2526 IKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPLTDQTV 2585

Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782
            AE+Q A FE     V +P  + EWLR+G  +  +N + +  D     L +     +D G 
Sbjct: 2586 AESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2642

Query: 1783 YT 1784
            YT
Sbjct: 2643 YT 2644



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYIS-LDMLSLNIQDSGEYTCRAVSATGVAETKA 724
            P ++ +W K G+ I  S +  SI    YIS L++L   + D GEYTC+A +  G     A
Sbjct: 4364 PNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 4422

Query: 725  VLHVT 729
             L VT
Sbjct: 4423 TLTVT 4427



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 76/367 (20%), Positives = 143/367 (38%), Gaps = 39/367 (10%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V+   P FT  ++D    E      +  +     P   V+W ++G  I+ S       D 
Sbjct: 5516 VLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKTDG 5572

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
                L +K     D G YTC    + G   TS  L ++ +     E +    L  ++ +E
Sbjct: 5573 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR-----EIKLVRPLHSVEVME 5623

Query: 1826 -DSSRYQRR-EDVEVAVNQAPRFITQLNGPT-KLSEGQSAH----YECRIEPYPDPNMRV 1878
             +++R++    + ++  N   +    L  P  ++ E    H    + CR++     + + 
Sbjct: 5624 TETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQA 5683

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAA-LDILTVYGEDSGEYTCK-AINNLGQAVSSIRLNV 1936
                   V  S H        G    L  +TV   ++  + C+ +  ++          +
Sbjct: 5684 -----ANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKL 5738

Query: 1937 QSKESIIRDSQ---HESALEKIQYLEDDSRYKRAVQD-----DSFVVEKP-QFGKPIKNA 1987
            +  + ++  S+   H   L  ++ LED    +   +D     + FV E P +F KP+++ 
Sbjct: 5739 EPSDKVVPRSEGKVHTLTLRDVK-LEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQ 5797

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
             V EG    LE  ++  N    +V+W+ NG  + +  +++   D     L I     ED 
Sbjct: 5798 TVEEGATAVLECEVSREN---AKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDI 5854

Query: 2048 GTYMCKA 2054
             TY C A
Sbjct: 5855 KTYTCDA 5861



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/66 (25%), Positives = 34/66 (51%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G   +   ++ G P P +TW K G+ L+   + ++I       L+++   ++D G Y + 
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11485

Query: 340   AENPNG 345
             A+N +G
Sbjct: 11486 AKNSSG 11491



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 21/69 (30%), Positives = 35/69 (50%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G +      + G P P V+W K+G  L  +   ++    N  TL + +  + DSG Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869

Query: 337   TLLAENPNG 345
             T+ AEN +G
Sbjct: 12870 TITAENSSG 12878



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 4/108 (3%)

Query: 467   ARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLN--VREGEPVVLNARAVGTPTPRIT 523
             A N++GE      + V+ ++ VVAP   ++    L    +E     L     G P P ++
Sbjct: 13460 AENENGEGT-PSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13518

Query: 524   WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             W+K   P+  +  + + +    +TL +   + SDA  Y  T +NVAG+
Sbjct: 13519 WKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGT 13566



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/82 (29%), Positives = 37/82 (45%)

Query: 4512  VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
             + PS  L     NV + + +++D    G     V W K+G+ ++   R  +       +L
Sbjct: 18896 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL 18955

Query: 4572  LILEAYPQDSGKYECVAINSAG 4593
              I EA  +D G YE    NSAG
Sbjct: 18956 SIKEASKEDVGTYELCVSNSAG 18977



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 19/76 (25%), Positives = 39/76 (51%)

Query: 4637  GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
             G +++    I GKP PT++WYK DK ++ +    +  T D  ++ I +A   + G Y+  
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20449

Query: 4697  AYNSAGRVTVAAKLKV 4712
               N+    +   ++++
Sbjct: 20450 LRNAMASASATIRVQI 20465



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 6/135 (4%)

Query: 4578  PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
             P D  ++  +A N+ G     ++    +  T+D+  P        PE  + L   I+  G
Sbjct: 21423 PGDRYEFRIIARNAVGTISPPSQSS-GIIMTRDENVPPI--VEFGPEYFDGL---IIKSG 21476

Query: 4638  QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
             +++     + G+P+P V W+K    I+     +++      +L + +A  +  G Y   A
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEA 21536

Query: 4698  YNSAGRVTVAAKLKV 4712
              N++G      K+KV
Sbjct: 21537 KNASGSAKAEIKVKV 21551



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 12/133 (9%)

Query: 2366  EIPEPVTR------QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI 2419
             EI EP+T       Q P F + L+N+ N++    A   C++   G P   V+W+R  K I
Sbjct: 24415 EISEPITPKSDVPIQAPHFKEELRNL-NVRYQSNATLVCKV--TGHPKPIVKWYRQGKEI 24471

Query: 2420  EDSSRITKTHDF--GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE 2477
                    +  +F  GY  + I+ V D+D  VY  RA+N  G               I L 
Sbjct: 24472 IADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL- 24530

Query: 2478  TQHPEGMKKIQKL 2490
              +  EGM  +  L
Sbjct: 24531 PKTLEGMGAVHAL 24543



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 768   QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-- 825
             Q P F   L++L    +  NA    ++T    P   V+WY+ G+ I A      I  F  
Sbjct: 24429 QAPHFKEELRNLNVRYQS-NATLVCKVT--GHPKPIVKWYRQGKEIIADGLKYRIQEFKG 24485

Query: 826   GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             GY  L I  +  +DA  Y VRA N+ G    TAS+ V
Sbjct: 24486 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 72/328 (21%), Positives = 120/328 (36%), Gaps = 35/328 (10%)

Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
            + + G G    P F        +  G  V    +V G     VYW K+G  +    R K+
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKV 1084

Query: 4563 L--EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS-----LPATKDKPKPQ 4615
               ++ G   L+I   +  D+G+Y  V  N  GE    A  +       L  ++ +   Q
Sbjct: 1085 SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQ 1144

Query: 4616 TK--AANAPPEIIEPLKDKIVAEGQAIEFSC------KIVGKPLPTVQWYKGDKLIKPSK 4667
            T+  A    PE+ E     + +E +  E+        K + K    V+ Y  D+    S 
Sbjct: 1145 TQVTAFVQEPEVGETAPGFVYSEYEK-EYEKEQALIRKKMAKDTVVVRTYVEDQEFHISS 1203

Query: 4668 YFQMSRTADEYTL---RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
            + +      EY +    + E   ED  +   V  + +  V     L++            
Sbjct: 1204 FEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRI------------ 1251

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM-IHEGNNAVLLIGNT 4783
               ++  + EG    F  +++    P I W ++G  I     +QM   +   A L I   
Sbjct: 1252 ---KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVV 1308

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              ED G +T  A+   G    S KL V+
Sbjct: 1309 LPEDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 6/145 (4%)

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIK 1985
            + V+S  ++ + ++  ++ S+ +         E+ +  K    +   + E  P    P+ 
Sbjct: 4191 KGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLV 4250

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            +    EG  VHL  ++T   +    V WY   + V    +FK   D     L I     E
Sbjct: 4251 DTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE 4306

Query: 2046 D-TGTYMCKATNAVGEAVTTSSVKV 2069
            D  G Y+C+A N  G+  T++ + V
Sbjct: 4307 DHQGEYVCEALNDSGKTATSAKLTV 4331



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 42/183 (22%), Positives = 73/183 (39%), Gaps = 13/183 (7%)

Query: 4622 PPEIIEPLKDKIVAE----GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
            P + ++ +KD I+ E    G +  F C +V        W K    I+ S   +      +
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRFIADGKD 4675

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
              L I +    D G+Y CV        T  AKL V   ++       T   ++ V +GQP
Sbjct: 4676 RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV---EELPVRFVKTLEEEVTVVKGQP 4732

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE--GNNAVLLIGNTYEEDTGTFTCRA 4795
                 ++    +  + W ++G ++ E P  +++    G    L I +  + D GT+T   
Sbjct: 4733 LYLSCELNK--ERDVVWRKDGKIVVEKPG-RIVPGVIGLMRALTINDADDTDAGTYTVTV 4789

Query: 4796 TTA 4798
              A
Sbjct: 4790 ENA 4792



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 25/77 (32%), Positives = 36/77 (46%)

Query: 494  VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
            V+  + L V+ G  + L A   G P P+ITW K  + +  +  + I      ST+ I  +
Sbjct: 7197 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS 7256

Query: 554  KASDAAWYQCTAQNVAG 570
            K SD   Y   A NV G
Sbjct: 7257 KRSDTGTYIIEAVNVCG 7273



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 5/106 (4%)

Query: 4511  IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             ++PP+F L      V +G+ +++D    G     V W K+   ++   R      +    
Sbjct: 15648 VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSL 15707

Query: 4571  LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
             L I +A  +D G Y     NSAGEA      +V      DKP P T
Sbjct: 15708 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV-----LDKPGPPT 15748



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 4120  VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTG 4178
             VT + GE A+  C++ G P P + W   G  ++   +YK++ DG  H   +    Q D G
Sbjct: 24045 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEG 24104



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGYVALDIASVRAED 1112
            +I+EG    F  ++         + WY +GK+I    R Q  +   G  +L I  V  ED
Sbjct: 1255 RILEGMGVTFHCKMSGYP--LPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312

Query: 1113 SGVYTVVARNAAGEAQLSASMTVE 1136
             G+YT  A N  G A  S  + VE
Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF-NFGYVSLNIMHLRAEDAGS 842
            EG    F  +++    P  ++ WYKDG+ I    R    F   G  SL I  +  ED G 
Sbjct: 1258 EGMGVTFHCKMSGY--PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315

Query: 843  YTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
            YT  A N  G AI +  + V   + + A   IP
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP 1348



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 3/87 (3%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V   Q   F  +L       +   A +EC      +P ++V+WY +G  +  G +YR  +
Sbjct: 2122 VQAKQLITFTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHS 2178

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINN 1924
            D     L ILT+   D+ +Y+C  + +
Sbjct: 2179 DRKVHFLSILTIDTSDAEDYSCVLVED 2205



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 13/136 (9%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P  K  I + + +  G  A F   ++   +  +R +W K GR +  S + +   +    +
Sbjct: 4337 PVIKRKI-EPLEVALGHLAKFTCEIQSAPN--VRFQWFKAGREIYESDKCSIRSSKYISS 4393

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I    V D G YTC+A N  G  + +A LT+            PGG +K++ L    +
Sbjct: 4394 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTV----------PGGEKKVRKLLPERK 4443

Query: 1029 YSKRTEEEVKITQKPR 1044
               + E  +K   + R
Sbjct: 4444 PEPKEEVVLKSVLRKR 4459



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 78/364 (21%), Positives = 136/364 (37%), Gaps = 31/364 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P FT +++D   V E   V   C +     P   + WF +G+            D     
Sbjct: 5521 PYFTGKLQDYTGV-EKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKTDGKKRM 5576

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L +      D G+YTC      G+  T+ K+    +     E +L + +   ++ E E  
Sbjct: 5577 LILKKALKSDIGQYTCDC----GTDKTSGKLDIEDR-----EIKLVRPLHSVEVMETETA 5627

Query: 3815 RISDAPKEEPIVST---PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            R      E+ I +      + + Q     ++E   +        + D    ++ ++   +
Sbjct: 5628 RFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVD-FQAANV 5686

Query: 3872 LPSGHRYRTVYDMGFVS-LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              S H       +G +  L  + V A ++  + C     + +   +  +  KKL      
Sbjct: 5687 KSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCEL--SYEDIPVEWYLKGKKLEPS--D 5742

Query: 3931 NQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLY---DVDKKQPP-RFVTQIQSQTSLV 3986
              VPR   +   LT  +  ++    EV LT  D     ++  K+PP  F   ++ QT + 
Sbjct: 5743 KVVPRSEGKVHTLTLRDVKLED-AGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQT-VE 5800

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEY 4046
            E  T   EC+   V   N KV+WF NG  +L   ++  + D     +      PED   Y
Sbjct: 5801 EGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTY 5857

Query: 4047 LCRA 4050
             C A
Sbjct: 5858 TCDA 5861



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 34/117 (29%), Positives = 49/117 (41%), Gaps = 6/117 (5%)

Query: 246   GESDVQISTEIDRSLGPVSPPKI---AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
             GESD     E       + PP++   A   R   ++ G   +    + G P P+VTW K 
Sbjct: 10699 GESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKE 10758

Query: 303   GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC-IVTSGYLAVESP 358
              +      K  I  T   + L +RN    D G Y+L  ENP G   V+   L ++ P
Sbjct: 10759 DRDA--PTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKP 10813



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 18/59 (30%), Positives = 33/59 (55%)

Query: 287   VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             + + G P P+ +W K G+ +  S+  +I +T   + L ++   + D+G YT+ A NP G
Sbjct: 13904 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 5/104 (4%)

Query: 4511  IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             ++ P       + +V  GQ ++++  ++G     + W K+G  ++   R  + +     T
Sbjct: 16730 VIEPDVKPAFSSYSVQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16789

Query: 4571  LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             L I E +  D G+Y     N  G+     E V     T DKP P
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKTASIEIV-----TLDKPDP 16828



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ G  A+  +   G P P +TW +       ++K +I    N+T L + N  ++D+G Y
Sbjct: 17539 VRAGGSARIHIPFKGRPMPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAGKY 17596

Query: 337   TLLAENPNG 345
              L  EN +G
Sbjct: 17597 ILKLENSSG 17605



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/125 (20%), Positives = 51/125 (40%), Gaps = 1/125 (0%)

Query: 4690  EGDYKCVAYNSAGRVTVAAK-LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             E  ++  AYN  G+       + V   D         P     +  G+  + +  +  + 
Sbjct: 17783 EYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRP 17842

Query: 4749  KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +P I W+++G  + +T    +     + VL I    ++D G +T  AT +AG    +  +
Sbjct: 17843 RPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 17902

Query: 4809  VVKSK 4813
             +V  K
Sbjct: 17903 IVLEK 17907



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 4622  PPEIIE---PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             PPEI     P     V  G  ++    I GKPLP V   +    +K +  F    TA+  
Sbjct: 19976 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20035

Query: 4679  TLRISEAFPEDEGDYKCVAYNSAG 4702
             T+ + E+   D G Y+  A NS+G
Sbjct: 20036 TINLKESVTADAGRYEITAANSSG 20059



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 4/110 (3%)

Query: 1703  QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
             + +V  QAP F   ++++ V     A    ++   G PK  V+W R G  I A      +
Sbjct: 24423 KSDVPIQAPHFKEELRNLNVRYQSNATLVCKV--TGHPKPIVKWYRQGKEIIADGLKYRI 24480

Query: 1763  HDF--GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
              +F  GY  L +  V  +D+  Y  RA N+ G    +++L V+  A + L
Sbjct: 24481 QEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL 24530



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 16/115 (13%)

Query: 4080 HMKSIEK--IREMEASW-QVTPEQVVEESKARCPPVFVSLPDAVT-----------VEEG 4125
            H+ S E+  I+E+E    + T E+++EE       V +S  +AV            + EG
Sbjct: 1200 HISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEG 1259

Query: 4126 EWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYDTG 4178
                F C+++G+P P++ W  +G  I +G RY++ +  DG     IP     D G
Sbjct: 1260 MGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEG 1314



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 639  FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF-RFGYISLD 697
            F + +K+   +EG  + F  ++   G P  KI W K+G+ I+   R+   F + G  SL 
Sbjct: 1247 FDLRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLR 1304

Query: 698  MLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            +  +  +D G YT  A +  G A     L+V P A +   +  P TL+ + ++   S
Sbjct: 1305 IPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIP-TLEPVSRIRSLS 1360



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 4/123 (3%)

Query: 1147 HRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGD 1206
            H+G Y     + +S       ++  + ++ PV  + +  P  V+ G      C ++    
Sbjct: 4308 HQGEYV-CEALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSA-- 4363

Query: 1207 PTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
            P +R +WF  GR +    +          +L+I+     D GEYT +A N  GS   +A 
Sbjct: 4364 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 4423

Query: 1267 VRV 1269
            + V
Sbjct: 4424 LTV 4426



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 49/208 (23%), Positives = 91/208 (43%), Gaps = 24/208 (11%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V ++ G+ A ++  L     + + +EW+  GK +E S ++       +  L +   K  D
Sbjct: 5708 VTVTAGETATFDCEL---SYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLED 5764

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            +G     A +    A + VK   V+        FT  +++ + +++G +A  EC V    
Sbjct: 5765 AGEVQLTAKDFKTHANLFVKEPPVE--------FTKPLED-QTVEEGATAVLECEV---S 5812

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF-TR 3236
              + K++W+ NG  +  S + + V+D     L I      D   Y C A     +DF T 
Sbjct: 5813 RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA-----KDFKTS 5867

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELE 3264
              +N       ++E L+P +  ++RE E
Sbjct: 5868 CNLNVVPP---HVEFLRPLTDLQVREKE 5892



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/60 (36%), Positives = 31/60 (51%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W KDG+ V+AS R+T   +     L +      DAG YT    N +G AT S N+ ++
Sbjct: 7921 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 7980



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 36/171 (21%), Positives = 67/171 (39%), Gaps = 12/171 (7%)

Query: 194  QGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIS 253
            QGY  E+ R  +            T  F V+  +   + E  FR       +GES+  + 
Sbjct: 8830 QGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYE--FRVKAVNE-IGESEPSLP 8886

Query: 254  TEI---DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL---- 306
              +   D  + P    +++ +    K++ G        ++G P P++ W KN   +    
Sbjct: 8887 LNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPT 8946

Query: 307  --INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
              +   K E+  +   T L +    + D G YT+ A N  G +  + ++ V
Sbjct: 8947 DALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 8997



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 6/83 (7%)

Query: 1058  GQSAHFEARVE--PQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGV 1115
             GQ+    ARV+  P+ D+T T E    GK +    R+    D   V L I      D G 
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKE----GKVLVREKRVDLIQDLPRVELQIKEAVRADHGK 11481

Query: 1116  YTVVARNAAGEAQLSASMTVETR 1138
             Y + A+N++G AQ SA + V  R
Sbjct: 11482 YIISAKNSSGHAQGSAIVNVLDR 11504



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL--KSTFDFGLVTLSINSLRNDDSGI 2714
             G+   ++A +  +  P   I+W K    L+  ARL  KST DF   +LS+      DSG 
Sbjct: 16061 GESFKVDADIYGKPIPT--IQWIKGDQELSNTARLEIKST-DFA-TSLSVKDAVRVDSGN 16116

Query: 2715  YTCKATNLLGEAVSTASIKIEDR 2737
             Y  KA N+ GE   T ++K+ DR
Sbjct: 16117 YILKAKNVAGERSVTVNVKVLDR 16139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
             G +   +  + G P P + WT+    L  C K S++Y  +    + +IK     D G+YT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKR--ATAVIKFCDRSDSGKYT 22622

Query: 146   CTARNQYGEAICSVYIQ 162
              T +N  G    SV ++
Sbjct: 22623 LTVKNASGTKAVSVMVK 22639



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/106 (31%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 368   SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
             S+Y     + E  ERIEI +  LA    K    R    G   R    V+GRP P +TW  
Sbjct: 22929 SEYSESIAEIEPVERIEIPDLELADDLKKTVTIR---AGASLRLMVSVSGRPPPVITW-- 22983

Query: 428   NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
               +Q  D  +  I+        L++  V   D+G  T  A N+SG+
Sbjct: 22984 -SKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGK 23028



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033
            + P F +P+++  V EG     EA ++    P   V W+ +G+ +        + ++  G
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
               L I      ++G Y  KATN  G+A +T+ + V A++
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFD 1366
            QAP F++ L ++  +EG+    E  +   G     V WF +G+ I T      + ++   
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
               L + +V   +SG Y+ +ATN  G+A ++  L V A+
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/100 (24%), Positives = 47/100 (47%), Gaps = 3/100 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F   ++ ++ V +G  V    RV  + +P ++  ++ +G    +        +    
Sbjct: 103  PPNFVQRLQ-SMTVRQGSQVRLQVRVTGIPNPVVK--FYRDGAEIQSSLDFQISQEGDLY 159

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            +L I   Y  D+G Y+  ATN  G AT+TA++    + ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/97 (32%), Positives = 48/97 (49%), Gaps = 7/97 (7%)

Query: 2944 KIEWYFNGKVLEQGSRFKLTSDF---GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            KI WY +GK ++ G R+++  DF   G  +L +  V   D GIYT  A N +G A  S  
Sbjct: 1275 KIAWYKDGKRIKHGERYQM--DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGK 1332

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLED-SLRKEP 3036
            +Y      L   T  P   E + +I++L   S+ + P
Sbjct: 1333 LYVEPAAPLGAPTYIPT-LEPVSRIRSLSPRSVSRSP 1368



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 37/118 (31%), Positives = 50/118 (42%), Gaps = 5/118 (4%)

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            +P  IE     + P     + S + + +G  AHF  RV    DP    +W+ NG KI   
Sbjct: 2019 KPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRVVGKPDPEC--EWYKNGVKIERS 2075

Query: 2156 HR-YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQ 2212
             R Y    +     L I    AEDS + M KA N  GE  +   L V   + +I  TQ
Sbjct: 2076 DRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA-KQLITFTQ 2132



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 6/97 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P   TP+ D +S +EG   H    +     +   V W  + + V +  +     +     
Sbjct: 4243 PMIHTPLVDTVS-EEGDIVHLTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYT 4297

Query: 969  LTIKSVTVHD-AGHYTCRAYNAIGQATTSANLTIVTK 1004
            L I  V   D  G Y C A N  G+  TSA LT+V +
Sbjct: 4298 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 4334



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 1314  SRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDL 1372
             S A+ ++ TV+ GTNV L+  +   G     V W  +G  +K     + A + +   L+L
Sbjct: 12801 SVAMKSLLTVKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 12858

Query: 1373  LSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
              SV  +DSG YT  A N  G    +  L+V+ K
Sbjct: 12859 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/71 (35%), Positives = 34/71 (47%)

Query: 2004  VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
             +  PT  V W+ +  P++Q  R           L I  A  ED G Y+ K TN+ GEA+ 
Sbjct: 15675 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 15734

Query: 2064  TSSVKVDAKSG 2074
             T +V V  K G
Sbjct: 15735 TLNVIVLDKPG 15745



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 20/66 (30%), Positives = 31/66 (46%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
             G   +  + ++G P P  +WF  G +L  S +  + T      L +R T   D+G YTL 
Sbjct: 23256 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23315

Query: 340   AENPNG 345
              +N  G
Sbjct: 23316 LKNVTG 23321



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 48/184 (26%), Positives = 80/184 (43%), Gaps = 10/184 (5%)

Query: 3774  NKWGSATTTA-KITCSAKRDIVLESQLPQGMSGEKIK-ELERGRISD--APKEEPIVSTP 3829
             NKW S TT   + T  + ++++   +    +  E +  E E   IS+   PK +  +  P
Sbjct: 24372 NKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAP 24431

Query: 3830  PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYR-TVYDMGFV 3887
               F  ++++  V         C+V     PK  ++WYR GK ++  G +YR   +  G+ 
Sbjct: 24432 -HFKEELRNLNVRYQSNATLVCKVTGH--PKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24488

Query: 3888  SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQME 3947
              L I  V  +D+  Y  RA N  G     A++   ++P  I   +   GM    AL    
Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTLEGMGAVHALRGEV 24547

Query: 3948  ATIK 3951
              +IK
Sbjct: 24548 VSIK 24551



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/84 (27%), Positives = 35/84 (41%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F Q  ++    +G  A FE  + G P P VSW R    +       ++ +   G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155
            I  +   + G Y+  A N  G+A
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA 89



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 1/82 (1%)

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
            V EG+ A+F+ ++T   +P + W   G LI ++  F++ ++G +  L I +    DTG  
Sbjct: 1806 VLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIH-YLDIVDCKSYDTGEV 1864

Query: 4792 TCRATTAAGQVETSAKLVVKSK 4813
               A    G +E   KL ++ +
Sbjct: 1865 KVTAENPEGVIEHKVKLEIQQR 1886



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 4/99 (4%)

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            FK  +I    + + P   + +Q+   + +G  AHF  R+  VG P  + EW++N   IE 
Sbjct: 2018 FKPDKIELSPSMEAPKIFERIQS-QTVGQGSDAHFRVRV--VGKPDPECEWYKNGVKIER 2074

Query: 2422 SSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S RI     +     + I  V  ED    M +A N+ GE
Sbjct: 2075 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE 2113



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 3284 FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343
            F  ++QDV    +   A FE       +P +KV+W+ +G ++  G +YR   D  +  L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 3344 ILYCYEENSGEYECV 3358
            IL     ++ +Y CV
Sbjct: 2187 ILTIDTSDAEDYSCV 2201



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 42/175 (24%), Positives = 68/175 (38%), Gaps = 13/175 (7%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            + +K  +D    E     F+  V+    P V WF    +I+    H+ LV+E   H LM+
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHR-LVSERKVHKLML 2807

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             N++ SD+G  T V     G+   +C+  +     V      +    + V E +      
Sbjct: 2808 QNISPSDAGEYTAVV----GQ--LECKAKLF----VETLHITKTMKNIEVPETKTASFEC 2857

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
                   P + W K+GV I  + + +I   G    L I      D+A Y     N
Sbjct: 2858 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2911



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 10/96 (10%)

Query: 771  QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-S 829
            +F + ++D+  L++ R A FE +   VS+P + V+W KD + +  + RI  I    YV  
Sbjct: 3013 EFRKHIKDIKVLEKKR-AMFECE---VSEPDITVQWMKDDQELQITDRI-KIQKEKYVHR 3067

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            L I   R  DAG YTV A    G  +STA + V  R
Sbjct: 3068 LLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3099



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERD-SGI 2983
            EG ++HL   +    +    + WYF  K++    +FK   D    TL +  V   D  G 
Sbjct: 4256 EGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4311

Query: 2984 YTCKAYNKRGEAFTSS 2999
            Y C+A N  G+  TS+
Sbjct: 4312 YVCEALNDSGKTATSA 4327



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 4/125 (3%)

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
            TE +  +   + + D+ +  T  ++ + ++A AP   +  +  +V  G + +F C +   
Sbjct: 4305 TEDHQGEYVCEALNDSGKTATSAKLTVVKRA-APVIKRKIEPLEVALGHLAKFTCEIQSA 4363

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P     WF   R+I +  + K  +  S    +L I    + D G  TC A N+ G  +  
Sbjct: 4364 PNVRFQWFKAGREIYE--SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT 4421

Query: 478  CRLNV 482
              L V
Sbjct: 4422 ATLTV 4426



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVR----FECRVEPKEDPKLRIEWYRNGKLLP 3873
            +AP    + + P KF+ +IK   + ESE V     FEC V P         W ++G  + 
Sbjct: 4606 EAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPST---AITTWMKDGSNIR 4662

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
               ++R + D     L I+ V   D+GEY C       E  + A +  ++LP
Sbjct: 4663 ESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP 4714



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 14/148 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMV-VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            ++WF +G+ I  S +  ++ A G+  +L+I      D G Y C       +A ++V+   
Sbjct: 5195 VKWFKDGEEIVPSPKY-SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARL 5253

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            ++    +KP +   +        G++AHFE   + + +PD+  +W   GQP+  S   + 
Sbjct: 5254 IEV---EKPLYGVEVFV------GETAHFE---IELSEPDVHGQWKLKGQPLTASPDCEI 5301

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            + D    +L +   Q   +GE   +A N
Sbjct: 5302 IEDGKKHILILHNCQLGMTGEVSFQAAN 5329



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 9/100 (9%)

Query: 2222 QLEAQGHSTRIE--VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
            QL A+   T     V+EP   P  F   L   T V EG TA  EC+V      N +++++
Sbjct: 5769 QLTAKDFKTHANLFVKEP---PVEFTKPLEDQT-VEEGATAVLECEVSR---ENAKVKWF 5821

Query: 2280 HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKA 2319
             NG  +  + ++ I  D     L I  C PED   Y+  A
Sbjct: 5822 KNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)

Query: 4613  KPQT-KAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             KP T K   APP +    +DK+ +  G+A   + +  GKP P V W+K +  +       
Sbjct: 10310 KPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTH 10369

Query: 4671  MSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
             +  T     L   +A   D G Y  V  NS G
Sbjct: 10370 IKTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/112 (24%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 245   VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
             +G  D  I  E    L P S     +      ++ G   +F   + G P P   W  +G 
Sbjct: 10993 LGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGS 11052

Query: 305   RLINSNKHEIITTHNHTT-LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
               I +++H  + T N ++ L ++N  + D+G Y +   N  G    + +L V
Sbjct: 11053 E-IKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 21/69 (30%), Positives = 32/69 (46%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
             V  G+ ++     +G+P P V W+K +  +K +       T +   L I +A  ED G Y
Sbjct: 15662 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15721

Query: 4694  KCVAYNSAG 4702
                  NSAG
Sbjct: 15722 VVKLTNSAG 15730



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 2/90 (2%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P  +  F +     G + K E  + G P P ++WT+   PL +  + ++   +     +L
Sbjct: 16733 PDVKPAFSSYSVQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINV--TDSLDLTTL 16790

Query: 132   LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              IK+    D G+Y  T  N  G+   S+ I
Sbjct: 16791 SIKETHKDDGGQYGITVANVVGQKTASIEI 16820



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/78 (28%), Positives = 37/78 (47%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  R E +  G+PLP I+W R +  I+ S   +I     K++LI++     D   +   A
Sbjct: 17144 ETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRA 17203

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N  G+     N+ V ++
Sbjct: 17204 SNVAGSKSFPVNVKVLDR 17221



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 4620  NAPPEIIEP-LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
             +AP   ++P  KD IV   G+       I GKP+P V W K G +L + +   ++  T  
Sbjct: 18206 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18265

Query: 4677  EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             + TL + +    D G Y     N  G  ++   +KV
Sbjct: 18266 KTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 277   LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             ++ GA     V   G P P V W K    L    +  + TT + T+L + N  ++DSG Y
Sbjct: 19701 VKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYVDTTDSRTSLTIENANRNDSGKY 19758

Query: 337   TLLAEN 342
             TL  +N
Sbjct: 19759 TLTIQN 19764



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 4091  EASWQVTPEQVVEESKARCP-PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
             E+ W    E +  +S      P F      + V     A   C+VTGHPKP V W   G 
Sbjct: 24410 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24469

Query: 4150  TIV-NGSRYKL-TYDGMYH 4166
              I+ +G +Y++  + G YH
Sbjct: 24470 EIIADGLKYRIQEFKGGYH 24488



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FVQ L +   V +G  + L+ R+  + +P   V+++ +G  +     F+   +    +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVTGIPNPV--VKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I  A   D+G Y+V A N +G A TS    +++  + V   + +  +   Q+ E    
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRA-TSTAELLVQGEEEVPAKKTKTIVSTAQISESRQT 219

Query: 1297 RTKQ 1300
            R ++
Sbjct: 220  RIEK 223



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 3/94 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+S   + +G  V L+ +V     PN  ++++++G  + +    + + +  L +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVTGI--PNPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L I     +DSG Y+  ATN +G A STA + ++
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            +E P+  + I++  V +G   H    +    DP    EWY NG  +++  R    +    
Sbjct: 2029 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP--ECEWYKNGVKIERSDRIYWYWPEDN 2086

Query: 2035 VA-LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            V  L I    AED+ + M KA N  GE  + + + V AK
Sbjct: 2087 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG+ + +      +  PT  V W  +G+ V    R     D     L++  +  AD G
Sbjct: 7901 VIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAG 7958

Query: 1249 EYTVRAVNHLGSAHTSAIVRVI 1270
             YT+   N LGSA  S  V+VI
Sbjct: 7959 IYTITLENKLGSATASINVKVI 7980



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 2/61 (3%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDI-ASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            TV W+ +GK++ +++R+   +D     L++  SVRA D+G+YT+   N  G A  S ++ 
Sbjct: 7920 TVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DAGIYTITLENKLGSATASINVK 7978

Query: 1135 V 1135
            V
Sbjct: 7979 V 7979



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/64 (34%), Positives = 31/64 (48%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V W  +GK +    R+   ND     LE+    + DAG+YT    N+ G AT S  ++V 
Sbjct: 7921 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 7980

Query: 3651 GRQG 3654
            G  G
Sbjct: 7981 GLPG 7984



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/74 (29%), Positives = 40/74 (54%)

Query: 4523  VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
             V + +G+  RL+  V+G  P  + W K+GK+++   + +I   D +  L+  ++  +DSG
Sbjct: 14974 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15033

Query: 4583  KYECVAINSAGEAR 4596
              Y   A N  G A+
Sbjct: 15034 AYTLTATNPGGFAK 15047



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 782   LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
             +Q G +   E  +  +  P   + W KDG P+  ++R+          L+I     +D G
Sbjct: 17826 IQAGEDLKIEIPV--IGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 17883

Query: 842   SYTVRAVNKLGEAISTASIRV 862
              YTV A N  G A    S+ V
Sbjct: 17884 KYTVTATNSAGTATENLSVIV 17904



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 19/64 (29%), Positives = 30/64 (46%)

Query: 284   QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
             +  V   G P+  V W K+GQ L  + +  + ++   T+L ++   K D G Y L   N 
Sbjct: 18916 KIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS 18975

Query: 344   NGCI 347
              G I
Sbjct: 18976 AGSI 18979



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/86 (25%), Positives = 47/86 (54%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQK--PRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             + PP+I  K  P ++  ++ G++ +  + +SG P P+VT  ++G  L  + +     T  
Sbjct: 19974 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 20033

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
             + T+ ++ +  +D+G Y + A N +G
Sbjct: 20034 NLTINLKESVTADAGRYEITAANSSG 20059



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 3403  SMVRRKDTSVEEE--KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
             S  RR   S++ +   G+AP     + ++   + GE A    ++     P++K  WY  G
Sbjct: 24017 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTT-KLGEAAQLSCQIVGRPLPDIK--WYRFG 24073

Query: 3461  KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             K L    +++   D     L +     ED G Y C A N  GE  T++ + +Q
Sbjct: 24074 KELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/60 (28%), Positives = 32/60 (53%)

Query: 1077  VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             ++WY  GK++  + + +   D     L + +   ED GVYT +A N  GE + S+ + ++
Sbjct: 24067 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/64 (31%), Positives = 32/64 (50%)

Query: 666   PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAV 725
             PT +++W  NG  ++ SS+       G ++L++L  +  DSG Y     +  G A   A 
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYAT 25963

Query: 726   LHVT 729
             L VT
Sbjct: 25964 LDVT 25967



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 19/53 (35%), Positives = 28/53 (52%)

Query: 2538  PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             P+   +WY NGVEL+  S+   T+  G +TL+I     +D+G Y     N  G
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKG 25956



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 82/413 (19%), Positives = 159/413 (38%), Gaps = 55/413 (13%)

Query: 1017  LEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMT 1076
             LEK    E+ ++ S+ +EE     +   F   +     I EGQ    +A +   +D    
Sbjct: 26519 LEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMS----INEGQRLVLKANIAGATD---- 26570

Query: 1077  VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             V+W  NG ++T++   +         L I      D G+ T +++   G  +    +T+ 
Sbjct: 26571 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 26630

Query: 1137  TRSSIDTSSIHRGLYEKTRHIEESKFV-----EPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
                S   + I +   +     +   F      EP  +IE    + P+ +   S+   +S 
Sbjct: 26631 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISI---SSNVSISR 26687

Query: 1192  GKNIH-LECRLEPMGDP---TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADT 1247
              +N++ LE R   + D    T++ + F    S T         +    + +++  TS DT
Sbjct: 26688 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEP--SREVVLRTSGDT 26745

Query: 1248  ---GEYTVRAV-----------NHLGSAHTSAIVRV------------IERSDIVTDTQN 1281
                G ++ ++V           +   S+  S++  +            ++ S +   + +
Sbjct: 26746 SLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSS 26805

Query: 1282  EQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQT 1341
                I  +  LE +   +K ++  I  +  P+      +I   EG  + + C     G+ T
Sbjct: 26806 FMGISNMTQLESST--SKMLKAGIRGIP-PKIEALPSDISIDEGKVLTVACAF--TGEPT 26860

Query: 1342  MRVEWFCNGKPIKTGH--RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
               V W C G+ I +    RF      D   L ++ V  +D G+YT    N+ G
Sbjct: 26861 PEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +TTQAP  T  L++V + EG  A FE  +   PV +    V W+ + + + + +      
Sbjct: 1    MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQI 56

Query: 1631 NF--GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            +F  G   L I +    +SG Y+ +A N  G+A ++   +V ++
Sbjct: 57   SFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 46/180 (25%), Positives = 69/180 (38%), Gaps = 16/180 (8%)

Query: 396  KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
            K  ++ +V E K   F+C V+    P + W  N  +I      KI+V +   H L+I N 
Sbjct: 2840 KTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVV-QGKLHQLIIMNT 2897

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARA 514
            +  DS            E  F C  + +     V P  +      +N  E + +      
Sbjct: 2898 STEDSA-----------EYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEV-T 2945

Query: 515  VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            V        W K+GV I    + ++ T     +L+I      DAA Y   A   A STAT
Sbjct: 2946 VNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA-GKATSTAT 3004



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/90 (26%), Positives = 37/90 (41%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P+  +K++P  V     A+F  E    P    +W++    I  S    I +    S L I
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 4396

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +  V D   +   A N  G+  C+A L V
Sbjct: 4397 LRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/106 (22%), Positives = 53/106 (50%), Gaps = 3/106 (2%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E ++ P+++ +W+  G+ + +  +  + S     +L+++     D G YTCKA N+ G  
Sbjct: 4359 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 4418

Query: 2996 FTSSTVYCT--SKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQ 3039
              ++T+  T    +  + +    +  E  E++  L+  LRK P ++
Sbjct: 4419 SCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-LKSVLRKRPEEE 4463



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 7/93 (7%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            P EFT    D  + E ++A  EC    V+  + +V+WF NG  +L   + + + D     
Sbjct: 5787 PVEFTKPLEDQTVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRK 5843

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I      D   YTC A     +   SC L V
Sbjct: 5844 LVIHDCTPEDIKTYTCDAK----DFKTSCNLNV 5872



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 4/74 (5%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F  PL++++ +RE E A FE  L+     N KV+W+ +G  +K G ++         IL 
Sbjct: 5879 FLRPLTDLQ-VREKEMARFECELSRE---NAKVKWFKDGAEIKKGKKYDIISKGAVRILV 5934

Query: 3482 ISPTYPEDSGEYLC 3495
            I+    +D  EY C
Sbjct: 5935 INKCLLDDEAEYSC 5948



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 8/91 (8%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH--- 318
            P  PP I  K    +++EG +     ++ G P P +TWFK   +  ++ +  +  TH   
Sbjct: 9617 PDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNK 9675

Query: 319  ----NHTTLRVRNTQKSDSGHYTLLAENPNG 345
                +  TL +  +++SD+G YT+ A N  G
Sbjct: 9676 LVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 9706



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/137 (23%), Positives = 53/137 (38%), Gaps = 5/137 (3%)

Query: 4069  PGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVF--VSLPDAVTVEEGE 4126
             PG++  ++    +K+   + E E   +   E V+ +     P V   V+  D +TV  G+
Sbjct: 11370 PGLIEGNEYRFRIKAANIVGEGEP--RELAESVIAKDILHPPEVELDVTCRDVITVRVGQ 11427

Query: 4127  WARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXX 4185
               R   RV G P+P + W   G  +V   R  L  D       I +  + D GK  +   
Sbjct: 11428 TIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAK 11487

Query: 4186  XXXXXXXXXXXLKVIPR 4202
                        + V+ R
Sbjct: 11488 NSSGHAQGSAIVNVLDR 11504



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 22/71 (30%), Positives = 35/71 (49%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             + VR G+ + + AR  G P P ITW K+G  ++    + +  D     L I  A  +D  
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480

Query: 560   WYQCTAQNVAG 570
              Y  +A+N +G
Sbjct: 11481 KYIISAKNSSG 11491



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 8/170 (4%)

Query: 194   QGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE-SITKRYVGE-SDVQ 251
             QGY  E+        +T  T  +  +   ++  +     E +FR  +I K  VGE +DV 
Sbjct: 16373 QGYIVEKC-DVNVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP 16431

Query: 252   ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311
                 ++  L         +  +   ++ G   +  V + G P P V W K    + ++  
Sbjct: 16432 GPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAI 16491

Query: 312   HEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG---CIVTSGYLAVESP 358
              ++  T + T+L + N  + DSG YTL  EN +G     VT   L   SP
Sbjct: 16492 IDV--TSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSP 16539



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 263   VSPPKI---AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             + PP+I   A   +   L+  A  +  V + G P P V W K     I +++ +I  T +
Sbjct: 18605 IEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK--AEGILTDRAQIEVTSS 18662

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
              T L + N  + DSG Y L  EN +G
Sbjct: 18663 FTMLVIDNVTRFDSGRYNLTLENNSG 18688



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 2/79 (2%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
             V +G  I  +  I GKP P  +W K  + I        S T  E  L I EA   D G Y
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTE--LVIKEADRGDSGTY 23708

Query: 4694  KCVAYNSAGRVTVAAKLKV 4712
               V  N  G+  V  K++V
Sbjct: 23709 DLVLENKCGKKAVYIKVRV 23727



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/190 (21%), Positives = 75/190 (39%), Gaps = 11/190 (5%)

Query: 3044  TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
             +G  P      KD+     G+ A     ++  G     I+W+  GK +  S + +     
Sbjct: 24032 SGEAPGIRKEMKDVTT-KLGEAAQLSCQIV--GRPLPDIKWYRFGKELIQSRKYKMSSDG 24088

Query: 3104  GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                 L ++  +  D G Y+C ATN+ G+ E S KL          P+F       E    
Sbjct: 24089 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL-----LLQATPQFHPGYPLKEKYYG 24143

Query: 3164  GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQNHDSGE 3221
                +     V+ +  P   + W+H  + +++S    I+    +  +V+     + H +G+
Sbjct: 24144 AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTH-AGK 24202

Query: 3222  YVCRAYNKYG 3231
             Y  +  N +G
Sbjct: 24203 YKVQLSNVFG 24212



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSL 2833
            F   L ++V  EG    FE ++  S  P  ++ WF + + + + T       FS     L
Sbjct: 8    FTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I    + +SG Y+ KATN  G AT++  L
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 15/157 (9%)

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA 4723
            K   Y ++ R   +  L  ++   E+E   K +A    G++T+       +PD+ +  P+
Sbjct: 1977 KDESYEELLRKTKDELLHWTKELTEEEK--KALA--EEGKITIPT----FKPDKIELSPS 2028

Query: 4724 LTP------LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNA 4776
            +        ++   V +G  A F+ ++  K  P  +W + G  I  +        E N  
Sbjct: 2029 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVC 2088

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             L+I +   ED+ +   +A   AG+  + A L+V++K
Sbjct: 2089 ELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 2244 FVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLD 2303
            FV EL+    V E  +   EC V P    N+  ++YHN   L+S  ++ IT   G  +L 
Sbjct: 2223 FVKELQDI-EVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2278

Query: 2304 IQHCVPEDAGEYS 2316
            ++    ED GEYS
Sbjct: 2279 VKDVTKEDQGEYS 2291



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
            L+++E+ E      E     VS   ++ +WYHN+  LKS  ++T T+  G   L +    
Sbjct: 2227 LQDIEVPESYSGELE---CIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVT 2283

Query: 1644 PEDSGTYT 1651
             ED G Y+
Sbjct: 2284 KEDQGEYS 2291



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 64/331 (19%), Positives = 127/331 (38%), Gaps = 35/331 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            K+    +     FE  +  +  PV  W  K   +   +K+ +    +     L+++ I P
Sbjct: 2756 KDVTALENATVAFEVSVSHDTVPV-KWFHKSVEIKPSDKHRLVSERKVH--KLMLQNISP 2812

Query: 139  GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
             D GEYT       G+  C   +  E                   + +E     T  +  
Sbjct: 2813 SDAGEYTAVV----GQLECKAKLFVE-----------TLHITKTMKNIEVPETKTASFEC 2857

Query: 199  EQSR-QTQKVAYTNGTDHSSTDDFKV---DTFEYRLLREVSFRESITKRYVGESDVQIST 254
            E S      +   NG +   ++ FK+         ++   S  +S    +V  +D Q+S 
Sbjct: 2858 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND-QVSA 2916

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
             +      V+P  I    ++   +E     F+V ++        W KNG  + +++K ++
Sbjct: 2917 TLT-----VTPIMITSMLKDINAEEKDTITFEVTVNYEGIS-YKWLKNGVEIKSTDKCQM 2970

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
             T     +L +RN    D+  YT +A    G   ++  L VE+    + +  +   + + 
Sbjct: 2971 RTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHIKDIKVLEK 3026

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTE 405
            ++   E   E+SE  +  Q++K  Q+  +T+
Sbjct: 3027 KRAMFE--CEVSEPDITVQWMKDDQELQITD 3055



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            +K++   E     FE  +     P+M   WLKNG  IE S +F  + +     L +++ +
Sbjct: 2842 MKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2898

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTP 730
             +DS EYT       G  +  A L VTP
Sbjct: 2899 TEDSAEYT----FVCGNDQVSATLTVTP 2922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 56/262 (21%), Positives = 107/262 (40%), Gaps = 18/262 (6%)

Query: 1410 LESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLE 1469
            +ES++    E++ Y    SR K  D    +  +    V+  K  E++   +    E   E
Sbjct: 4161 VESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLKPSEEKE-ESSSE 4219

Query: 1470 PVTD--SNLKVEWFKNGQPVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVN--- 1523
              T+  + +K++  + G     G     P+ D      DI+ L    + I   + VN   
Sbjct: 4220 SGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLT---TSITNAKEVNWYF 4276

Query: 1524 ---LVGTDEVSCRLTCRSTTDIVR---STQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
               LV +DE    L  ++T  +V    +T++  G    + L D  K   +  +  V   A
Sbjct: 4277 ENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 4336

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P+    ++ +E+  G  A F   +   S   ++ +W+   + +    + +  ++    +L
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSL 4394

Query: 1638 DIMSCLPEDSGTYTCRAINALG 1659
            +I+     D G YTC+A N  G
Sbjct: 4395 EILRTQVVDCGEYTCKASNEYG 4416



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 3575 AHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
            A F C +   +  ++R +WF  G+ +    +    +      LEI      D G YTCKA
Sbjct: 4354 AKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 4411

Query: 3635 TNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNP 3694
            +N +G  + +  L V    G     +L    K   +    L+  L KR E   E+E    
Sbjct: 4412 SNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPE---EEEPKVE 4468

Query: 3695 PRFTVEIKDNIDVPEGGP 3712
            P+   ++K    VPE  P
Sbjct: 4469 PKKLEKVKKPA-VPEPPP 4485



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/106 (25%), Positives = 46/106 (43%)

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            +G S+    +E   +  P   P I  +  +  + EG      V     P P V+W K+G+
Sbjct: 7869 IGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGK 7928

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
             +  S++  +   H    L V  + ++D+G YT+  EN  G    S
Sbjct: 7929 EVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATAS 7974



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P      H+I  +EG  + +    + V   T  V W  +GK +K   R     +     L
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHL 7947

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            ++      D+G+YT    N+LG A  S  ++VI
Sbjct: 7948 EVPKSVRADAGIYTITLENKLGSATASINVKVI 7980



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/48 (41%), Positives = 29/48 (60%), Gaps = 1/48 (2%)

Query: 486  EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
            + + APK + R S L V+ G+ + L+A   G+P P ITW KD   I+P
Sbjct: 8179 DPIDAPKVILRTS-LEVKRGDEIALDASISGSPYPTITWIKDENVIVP 8225



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/108 (24%), Positives = 42/108 (38%), Gaps = 4/108 (3%)

Query: 56   GDRQPITAGRPGEPSPPIFEQIFKNA-RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE 114
            G+ QP+T   P EP     +   K   +   G   +    + G P P   WT+++    E
Sbjct: 8591 GETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEG---E 8647

Query: 115  CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
             +K  +  +       L+IK     D G Y  TA N  G    +  ++
Sbjct: 8648 LDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVE 8695



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 10/85 (11%)

Query: 503  REGEPVVLNARAVGTPTPRITWQ---------KDGVPIIPNPELRIHTDGGASTLDIPRA 553
            + G  + + A   G PTP+ +W+         KDGV  IP  + ++ T   +S + IP  
Sbjct: 9326 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPE-DAQLETAENSSVIIIPEC 9384

Query: 554  KASDAAWYQCTAQNVAGSTATRARL 578
            K S    Y  TA+N AG      R+
Sbjct: 9385 KRSHTGKYSITAKNKAGQKTANCRV 9409



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 9/97 (9%)

Query: 776  LQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYK-------DGRPITASSRITSIFNFGYV 828
            L++  E++EG N +  A++  V  PT+   W+K       +  P+   + +  +      
Sbjct: 9625 LKEFMEVEEGTNVNIVAKIKGVPFPTLT--WFKAPPKKPDNKEPVLYDTHVNKLVVDDTC 9682

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            +L I   R  D G YT+ AVN LG A     + V  R
Sbjct: 9683 TLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 9719



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/110 (25%), Positives = 44/110 (40%), Gaps = 4/110 (3%)

Query: 378   ETEERIEISEKALAPQF---VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
             +T   IE  EK + P     VK+ +   V  G   RF   + G P P   W  +  +I+ 
Sbjct: 10997 DTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKT 11056

Query: 435   DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
             D  H  +  ++ +  L I N    D+G       N +G       L V++
Sbjct: 11057 D-EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 11105



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 2/76 (2%)

Query: 2926  GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
             GQ + +  +V+ + +PD  I W   GKVL +  R  L  D   V L + +    D G Y 
Sbjct: 11426 GQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 11483

Query: 2986  CKAYNKRGEAFTSSTV 3001
               A N  G A  S+ V
Sbjct: 11484 ISAKNSSGHAQGSAIV 11499



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 2/105 (1%)

Query: 3683  EEITIEDEKPNPPR-FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
             E I  +DE   P       IKD + +  G  +  +  +  +G P  +  W   G+     
Sbjct: 13868 ETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNA-ISILGKPLPKSSWSKAGKDIRPS 13926

Query: 3742  SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
                   +      L I Y   +DAGEYT  ATN +G+     K+T
Sbjct: 13927 DITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVT 13971



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 1735  IPV-GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
             +P+ G PK  + W ++G+P++ + R+          L++K  + +D G Y     N +G+
Sbjct: 16754 VPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 16813

Query: 1794  AVTSSTLFVQSK 1805
                S  +    K
Sbjct: 16814 KTASIEIVTLDK 16825



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
             P  +  F       G + K E  + G P P +SW +   PL +  + ++   E+T   ++
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV---EETATSTV 17871

Query: 132   L-IKQIGPGDEGEYTCTARNQYGEA 155
             L IK+    D G+YT TA N  G A
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTA 17896



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/113 (21%), Positives = 46/113 (40%)

Query: 4391  EHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP 4450
             E    T   +V+  V+P +  +  K      V   E  +   +  G PLP+I W ++   
Sbjct: 19273 EPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIE 19332

Query: 4451  IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
             I+     +I +    ++L ++     D+  +    +N  GT   + N  V +K
Sbjct: 19333 IEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 4525  VTSGQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
             V +G++++++  + G +P+ V  W K+G +++   R +I+  D    L + +   +D+G+
Sbjct: 19304 VKAGEVLKINADIAG-RPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQ 19362

Query: 4584  YECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             Y     N AG       C V      DKP P
Sbjct: 19363 YVLTLKNVAGTRSVAVNCKV-----LDKPGP 19388



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 280   GADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTLRVRNTQ-KSDSGHYT 337
             G+  +  V   G P P +TWF +GQ+L+ NS    I  T ++T L ++N Q K+ +G Y 
Sbjct: 24146 GSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYK 24204

Query: 338   LLAENPNGCI 347
             +   N  G +
Sbjct: 24205 VQLSNVFGTV 24214



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/164 (24%), Positives = 67/164 (40%), Gaps = 10/164 (6%)

Query: 3075  TGDQSMVIEWFYNGKTIEA---SHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
             TG    +++W+  GK I A    +RI+  +  G   L I      D+  Y  RATN+ G 
Sbjct: 24455 TGHPKPIVKWYRQGKEIIADGLKYRIQE-FKGGYHQLIIASVTDDDATVYQVRATNQGGS 24513

Query: 3132  AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD-DPDMKIEWYHNGQ 3190
                +  LE    +K   P+    +  +  L+ G+    +   +P    PD  I W     
Sbjct: 24514 VSGTASLEVEVPAKIHLPKTLEGMGAVHALR-GEVVSIK---IPFSGKPDPVITWQKGQD 24569

Query: 3191  PMRHSTRIKTVSDFGFVVLDIAY-TQNHDSGEYVCRAYNKYGED 3233
              + ++   + +    F  L      +  D+G YV  A N++G D
Sbjct: 24570 LIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGID 24613



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 391   APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHA 449
             AP+     +   V  G+ TRF   V  +P  EV W+ N  ++++  + KI   N SG   
Sbjct: 25876 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQE--SSKIHYTNTSGVLT 25933

Query: 450   LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             L I +    DSG    V  N  GE +    L+V
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 4622  PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYT 4679
             PP+I     D  + EG+ +  +C   G+P P V W  G + I   +   F +  T D  T
Sbjct: 26831 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 26890

Query: 4680  LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             L I +   +D G Y     N  G  +    + +
Sbjct: 26891 LIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 9/149 (6%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G + +   L  +AE+  PP F      + + + S    + R+  + +    V+++ +G  
Sbjct: 87   GQATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPV--VKFYRDGAE 143

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            + +    +   +     L I   Y  D+G Y+  ATN  G AT + +L V+G      E 
Sbjct: 144  IQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EE 197

Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIE 3688
            ++P+       S  ++ E+   R E  IE
Sbjct: 198  EVPAKKTKTIVSTAQISESRQTRIEKKIE 226



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLR--GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            P F++   + R  + G A FE +L    +PT VV W     PL   N+  +R   + G  
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANR--LRMINEFGYC 1714

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL        D G  TC A N+YG
Sbjct: 1715 SLDYGVAYSRDSGIITCRATNKYG 1738



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 8/126 (6%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            FT  L ++    +   A FE     T +P +KV+WY +G  +  G ++R   D     L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK-RNIILESQ---LPKGMEGTIDKIAA 3537
            I      D+ +Y C    +     TTA + V+G     + E Q   +P+   G ++ I +
Sbjct: 2187 ILTIDTSDAEDYSCVLVED-ENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVS 2245

Query: 3538 LEGYSG 3543
             E   G
Sbjct: 2246 PENIEG 2251



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 7/89 (7%)

Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIAS 1107
            PLK  N ++EG  A  E +V    D+T +V+WY N +QI   +R+Q         L I  
Sbjct: 2404 PLKDVN-VIEGTKAVLECKVSVP-DVT-SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINR 2460

Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
              A D G Y ++     G  + + +++VE
Sbjct: 2461 THASDEGPYKLI----VGRVETNCNLSVE 2485



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 44/206 (21%), Positives = 75/206 (36%), Gaps = 16/206 (7%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            D   +Y    + R++  R+ + E  +  + ++  QD     G    F   +  +   EV 
Sbjct: 6390 DDECEYACGVEDRKSRARLFVEE--IPVEIIRPPQDILEAPGADVVFLAELN-KDKVEVQ 6446

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
            W  N+  +     H+++ +E   H L I ++   D G    +A++K              
Sbjct: 6447 WLRNNMVVVQGDKHQMM-SEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKL-------- 6497

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
             E   APK       L V  G+P+ +       P     W K+  P+       I T   
Sbjct: 6498 -ELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAE 6553

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
             ++  I  AK  D   Y+   QN  G
Sbjct: 6554 QTSFRILEAKKGDKGRYKIVLQNKHG 6579



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 5/112 (4%)

Query: 377  RETEERIEISEKALAPQF---VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR 433
            R TEE I+  +   AP+    VK+     V  G        VTG+P P++TW   D  ++
Sbjct: 7177 RPTEE-IQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7235

Query: 434  DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             D     + N      + I +   SD+G     A N  G       +NV++K
Sbjct: 7236 QD-KRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7286



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 289   LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +SG P P VTW  N + L    +  I TT   +++ ++N Q+S  G Y+LLA+N  G
Sbjct: 10051 VSGKPPPTVTWNMNERTL--PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 10105



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 6/137 (4%)

Query: 2606  IIDQAMRPESWE-QIQLK----EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHV 2660
             ++D+ +  + +E ++Q K    E+   K  E+ V   +Q+ P+    L     +  G  +
Sbjct: 11664 MVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQK-PVLDLKLSGVLTVKAGDTI 11722

Query: 2661  YLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKAT 2720
              LEA V  +  P +     K+   LT   R+K          S+   +  D G Y   AT
Sbjct: 11723 RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTAT 11782

Query: 2721  NLLGEAVSTASIKIEDR 2737
             N  G  V+ A++ + D+
Sbjct: 11783 NTAGSFVAYATVNVLDK 11799



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 7/98 (7%)

Query: 380   EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
             EE++E  +  L  +  K+    ++  G   R    + GRP PEV W   D +IRD     
Sbjct: 16437 EEKLEAPDIDLDLELRKII---NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRD---AA 16490

Query: 440   ILVNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAF 476
             I+   S   +L++ NV   DSG  T    N SG ++AF
Sbjct: 16491 IIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAF 16528



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 17/130 (13%)

Query: 637   PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-FGYIS 695
             P F   L +    EG  + FE R+  +  PT+K  W K+GQ +        I     Y +
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYA 25355

Query: 696   LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
             L +     +D+G Y   A +  G    +A L V             E L+Y +Q E  SK
Sbjct: 25356 LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV-------------ERLRYKKQ-EFKSK 25401

Query: 756   YQHQESIEEQ 765
              +H+  +++Q
Sbjct: 25402 EEHERHVQKQ 25411



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 20/69 (28%), Positives = 31/69 (44%)

Query: 1201  LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
             L     PT  V+W+HNG  +   S+       G + L+I+   + D+G Y     N+ G 
Sbjct: 25898 LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 25957

Query: 1261  AHTSAIVRV 1269
             A   A + V
Sbjct: 25958 ASDYATLDV 25966



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 19/163 (11%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSG 3119
            +E Q   +E  L  +G   + + W +  K I+ S + + + A G +  L +L     D G
Sbjct: 2499 TETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEG 2554

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             Y+  A       +++V    + K    +            + + Q A FEC V    +P
Sbjct: 2555 KYTFYAGENMTSGKLTVAGGAISKPLTDQT-----------VAESQEAVFECEVA---NP 2600

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            D K EW  +G+ +  +  I++ SD     L IA T+  D GEY
Sbjct: 2601 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY 2643



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 8/112 (7%)

Query: 1042 KPRFLG---PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            KPR +G   PLK    +  G++A F+  +  +    + VEWY  GK++  ++++    + 
Sbjct: 5695 KPRVIGLLRPLKDVT-VTAGETATFDCELSYED---IPVEWYLKGKKLEPSDKVVPRSEG 5750

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSA-SMTVETRSSIDTSSIHRG 1149
                L +  V+ ED+G   + A++    A L      VE    ++  ++  G
Sbjct: 5751 KVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEG 5802



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 19/65 (29%), Positives = 32/65 (49%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P  T+ W  +G++++A  R    +D     L++  +   D+G Y     NKLG A  +  
Sbjct: 7917 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 7976

Query: 2199 LKVAG 2203
            +KV G
Sbjct: 7977 VKVIG 7981



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 3/72 (4%)

Query: 414   RVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
             R +G+P P+V+WF ++  +  DD  H  +       AL       SDSG    V  N +G
Sbjct: 10344 RYSGKPKPKVSWFKDEADVLEDDRTH--IKTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401

Query: 473   ETAFQCRLNVIE 484
                  C++NV++
Sbjct: 10402 SRKGFCQVNVVD 10413



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 2657  GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
             GQ + + A+V+ R +P+  I W K G  L    R+    D   V L I      D G Y 
Sbjct: 11426 GQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 11483

Query: 2717  CKATNLLGEAVSTASIKIEDR 2737
               A N  G A  +A + + DR
Sbjct: 11484 ISAKNSSGHAQGSAIVNVLDR 11504



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 4/122 (3%)

Query: 4091  EASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWL--LNG 4148
             E+ W  T E VV+E   + P + + L   +TV+ G+  R    V G P P V W    + 
Sbjct: 11686 ESDWVKTEEVVVKEDLQK-PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDA 11744

Query: 4149  NTIVNGSRYKL-TYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR 4207
               +    R K+ T      F + K ++ D GK  V              + V+ +    R
Sbjct: 11745 TDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVR 11804

Query: 4208  GV 4209
              +
Sbjct: 11805 NL 11806



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 31/149 (20%), Positives = 66/149 (44%), Gaps = 9/149 (6%)

Query: 631   DRVYPPPQFIVPLKSVTAMEGG-KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
             + V P     V +KS+  ++ G  +  +  +   G P   + W K+G  ++ +       
Sbjct: 12792 ENVPPRIDLSVAMKSLLTVKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAM 12849

Query: 690   RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT----PRATIERTSQHPE--T 743
             +    +L++ S+N +DSG+YT  A +++G       L V     P A+++    + +   
Sbjct: 12850 QRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAM 12909

Query: 744   LQYIQQLEDYSKYQHQESIEEQTSQRPQF 772
             L +   LED         ++++ + RP +
Sbjct: 12910 LSWEPPLEDGGSEITNYIVDKRETSRPNW 12938



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/99 (22%), Positives = 43/99 (43%), Gaps = 4/99 (4%)

Query: 3047  PP--EFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
             PP  + +   K ++ +  G     +A++   G     + W  +G  ++ +  I+      
Sbjct: 12795 PPRIDLSVAMKSLLTVKAGTNVCLDATVF--GKPMPTVSWKKDGTLLKPAEGIKMAMQRN 12852

Query: 3105  MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
             +  LE+      DSG Y+  A N  G    ++KL+ +DK
Sbjct: 12853 LCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 1/93 (1%)

Query: 773   IRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNI 832
             ++ L DL  L +  N++F  ++     P   V W K   P+   +R++   +    +L +
Sbjct: 13487 LKGLPDLCYLAK-ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIV 13545

Query: 833   MHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
                +  DAG YT+   N  G    T SI+V  +
Sbjct: 13546 YDCQKSDAGKYTITLKNVAGTKEGTISIKVVGK 13578



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 7/102 (6%)

Query: 472   GETAFQCRLNVIEKEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
             GE A    + ++E+E  +AP F    E   TL VR G  + +     G P P +TW KD 
Sbjct: 14260 GEPAVIPDVEIVERE--MAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN 14317

Query: 529   VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             + +       I      + L IP     D   +  T +N AG
Sbjct: 14318 INL--KNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 14357



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/156 (23%), Positives = 68/156 (43%), Gaps = 13/156 (8%)

Query: 4548  LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             L NG+ ++ +  N ILE + T + L  +A    + ++  +A N+AG     +E   ++  
Sbjct: 14901 LPNGRWLKANFSN-ILENEFTVSGLTEDA----AYEFRVIAKNAAGAISPPSEPSDAITC 14955

Query: 4608  TKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
               D   P+ K       +    KD ++ + G+A      + G+P PT++W K  K ++ +
Sbjct: 14956 RDDVEAPKIK-------VDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGT 15008

Query: 4667  KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                ++        L   ++   D G Y   A N  G
Sbjct: 15009 AKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15044



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 50/195 (25%), Positives = 81/195 (41%), Gaps = 17/195 (8%)

Query: 3042  DDTGRPPEFTTV-FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
             DD   P     V FKD V +  G+    EA +  +G     +EW  +GK +E + ++   
Sbjct: 14957 DDVEAPKIKVDVKFKDTVILKAGEAFRLEADV--SGRPPPTMEWSKDGKELEGTAKLEIK 15014

Query: 3101  YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK-SKGQKPRFTTHIQNIE 3159
              A     L    +   DSG Y+  ATN  G A+    ++ +D+    + P   T + + +
Sbjct: 15015 IADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 15074

Query: 3160  GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV-VLDIAYTQNHD 3218
              +             P+DD   KI+  H     R ++R+   +    V V  +  T+   
Sbjct: 15075 CVLS--------WFPPLDDGGAKID--HYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124

Query: 3219  SGEYVCR--AYNKYG 3231
               EY+ R  A NKYG
Sbjct: 15125 GNEYIFRVMAVNKYG 15139



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 17/77 (22%), Positives = 35/77 (45%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  R +    G P+P + W+++   I+   + +I      + L +R    +   V+   A
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEA 21536

Query: 4486  ENRGGTAKCSANLVVEE 4502
             +N  G+AK    + V++
Sbjct: 21537 KNASGSAKAEIKVKVQD 21553



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 1459  GQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGI 1516
             G+     C++   P+ D    ++W++ G+ +    +++   D     L ++    ED G+
Sbjct: 24050 GEAAQLSCQIVGRPLPD----IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 24105

Query: 1517  YTCRAVNLVGTDEVSCRLTCRST 1539
             YTC A N VG  E S +L  ++T
Sbjct: 24106 YTCIATNEVGEVETSSKLLLQAT 24128



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/101 (23%), Positives = 42/101 (41%), Gaps = 2/101 (1%)

Query: 1302  REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
             ++  T+  AP+ +  + +     G N      +Q     T  V+W+ NG  ++   +   
Sbjct: 25868 QQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHY 25925

Query: 1362  AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                   + L++L  + +DSG Y    TN  GEA     L V
Sbjct: 25926 TNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 17/54 (31%), Positives = 30/54 (55%)

Query: 2406  PTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             PT +V+W+ N   +++SS+I  T+  G +++ I     +D G Y    +N  GE
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 25957



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/109 (22%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V   T  P F   ++  +++++G     + R+  I +    V++ +DG  +++S      
Sbjct: 97   VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVTGIPNPV--VKFYRDGAEIQSSLDFQIS 153

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                  +L I      D+G Y+  A N++G+AT++A L +  ++++ A+
Sbjct: 154  QEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 41/179 (22%), Positives = 67/179 (37%), Gaps = 13/179 (7%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D +V EG     +C+V+      V W++ND QI+ D   + +V +     L+I     S
Sbjct: 2406 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV-KGTKQRLVINRTHAS 2464

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D G    +     G     C L+V   E++   K +     L   E + VV       + 
Sbjct: 2465 DEGPYKLIV----GRVETNCNLSV---EKI---KIIRGLRDLTCTETQNVVFEVELSHSG 2514

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA-QNVAGSTATRA 576
               + W      I P+ + +I   G    L +      D   Y   A +N+     T A
Sbjct: 2515 ID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVA 2572



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/92 (28%), Positives = 42/92 (45%)

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            +GE   +++T    +   V   KI +  +N  + E  DA F V+L+      V W KNG 
Sbjct: 2640 IGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV 2699

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L ++ K+ I       +LR++N    D   Y
Sbjct: 2700 VLESNEKYAISVKGTIYSLRIKNCAIVDESVY 2731



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KDI+V E + A FE     V +P + V+W+++   ++ ++R+    +     L +
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLI 3070

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                  D+G YT  A    G  V+++ LFV+ +
Sbjct: 3071 PSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3099



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 5/89 (5%)

Query: 4727 LRDIVVYE----GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782
            ++DI++ E    G  A F+  ++     T  W+++G+ I E+P  + I +G +  L I +
Sbjct: 4624 IKDIILTESEFVGSSAIFECLVSPSTAITT-WMKDGSNIRESPKHRFIADGKDRKLHIID 4682

Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                D G +TC       +  ++AKLVV+
Sbjct: 4683 VQLSDAGEYTCVLRLGNKEKTSTAKLVVE 4711



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 40/181 (22%), Positives = 75/181 (41%), Gaps = 18/181 (9%)

Query: 3047 PP--EFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            PP  EF     D+  + E ++A +E  L     ++  ++WF +G  I+   +   +    
Sbjct: 5874 PPHVEFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGA 5929

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            + +L I      D   YSC          ++V LE       ++  FT ++ NIE + + 
Sbjct: 5930 VRILVINKCLLDDEAEYSCEVRTARTSGMLTV-LE-------EEAVFTKNLANIE-VSET 5980

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
             +    C V     P  ++ WY   + +  + R + +++    +L I      D+G Y C
Sbjct: 5981 DTIKLVCEV---SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 6037

Query: 3225 R 3225
            R
Sbjct: 6038 R 6038



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/102 (33%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 4079 KHMKSIEKIR-EMEASWQVTPEQ---VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRV 4134
            KHM +I+      E  + VT  Q   V E      P  FV   +  TV E + A F C++
Sbjct: 6290 KHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQL 6349

Query: 4135 TGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYD 4176
            +   K  V W  NG  I  G +YK   DG  H  I K  + D
Sbjct: 6350 S-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 6390



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            PKI    ++  +  G      V     P+    WFK  + L  S K  I TT   T+ R+
Sbjct: 6503 PKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPL--STK-TIDTTAEQTSFRI 6559

Query: 326  RNTQKSDSGHYTLLAENPNG 345
               +K D G Y ++ +N +G
Sbjct: 6560 LEAKKGDKGRYKIVLQNKHG 6579



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 10/100 (10%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF--------INDRQIRDDYNHKILVN 443
            P  + + +  +V EG       ++ G P+P +TWF          +  + D + +K++V+
Sbjct: 9620 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 9679

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            ++    L+I     SD+G+ T  A N  G  + + RLNV+
Sbjct: 9680 DT--CTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVL 9717



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 501   NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             +++ G+ + L+A   G P P++TW+K+     P  + RI      S L+I  A   D   
Sbjct: 10732 HIKVGDTLRLSAIIKGVPFPKVTWKKEDRD-APT-KARIDVTPVGSKLEIRNAAHEDGGI 10789

Query: 561   YQCTAQNVAGSTATRARL 578
             Y  T +N AGS     ++
Sbjct: 10790 YSLTVENPAGSKTVSVKV 10807



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 6/119 (5%)

Query: 371   ITDTQQRETEERIEISEKALAPQFVKV---CQDR-DVTEGKMTRFDCRVTGRPYPEVTWF 426
             + + + RE  E + I++  L P  V++   C+D   V  G+  R   RV GRP P++TW 
Sbjct: 11388 VGEGEPRELAESV-IAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITW- 11445

Query: 427   INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
               + ++        L+ +     L I     +D G     A+N SG       +NV+++
Sbjct: 11446 TKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDR 11504



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 286   QVQLSGNPRPRVTWFKNGQRLINSN-KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPN 344
             +  + G P P V W K+G+ L  +  + EI +T   TTL V++  ++D G Y L   N  
Sbjct: 18231 EADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVG 18290

Query: 345   G 345
             G
Sbjct: 18291 G 18291



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/74 (28%), Positives = 35/74 (47%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             + +R G  +VL+A   G P P+I W K    +    ++ +   G  +T  I     SD+ 
Sbjct: 22560 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22619

Query: 560   WYQCTAQNVAGSTA 573
              Y  T +N +G+ A
Sbjct: 22620 KYTLTVKNASGTKA 22633



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 40/159 (25%), Positives = 56/159 (35%), Gaps = 5/159 (3%)

Query: 3629  LYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE 3688
             L  CKA        V+ K  V       L       F+   ++ + + E       +T++
Sbjct: 23174 LEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQ 23233

Query: 3689  DEKPNPP-RFTVEIKDNIDVPEGGPVHFDCRVEPV-GDPTMRIDWFHNGRPFATGSRVHT 3746
             D +  P    +   +  I VP G PV     V P+ G P     WF  G       RV  
Sbjct: 23234 DLRVLPTIDLSTMPQKTIHVPAGRPVEL---VIPIAGRPPPAASWFFAGSKLRESERVTV 23290

Query: 3747  LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                     L I     RD GEYT    N  G+ + T K+
Sbjct: 23291 ETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23329



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 3/95 (3%)

Query: 3695  PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
             P    E+KD +    G      C++  VG P   I W+  G+      +    +D     
Sbjct: 24036 PGIRKEMKD-VTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT 24092

Query: 3755  LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
             L +      D G YTC ATN+ G   T++K+   A
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/147 (19%), Positives = 60/147 (40%), Gaps = 8/147 (5%)

Query: 1794  AVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGP 1853
             ++++ ++    ++ +++ S     +  + QLE S+       ++  +   P  I  L   
Sbjct: 26785 SMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM----LKAGIRGIPPKIEALPSD 26840

Query: 1854  TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH--RYRTSNDFGFAALDILTVYG 1911
               + EG+     C     P P   V W   G+ + S    R+   N      L I+ V  
Sbjct: 26841 ISIDEGKVLTVACAFTGEPTPE--VTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQK 26898

Query: 1912  EDSGEYTCKAINNLGQAVSSIRLNVQS 1938
             +D G YT    N  G   +++ ++++S
Sbjct: 26899 QDGGLYTLSLGNEFGSDSATVNIHIRS 26925



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 8/94 (8%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            F  H+K   K++E +    E +V   ++P++ ++W K+   L    R+K   +  +  L 
Sbjct: 3014 FRKHIKDI-KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLL 3069

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            I S R  D+G YT  A    G  VSTA + +E R
Sbjct: 3070 IPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 3099



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            K++E + A FE  V   S+  +TV+W  + +++   +RI+   +     L I S R  D+
Sbjct: 3022 KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078

Query: 1114 GVYTVVARNAAGEAQL 1129
            G YTVVA      A+L
Sbjct: 3079 GKYTVVAGGNVSTAKL 3094



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/137 (21%), Positives = 59/137 (43%), Gaps = 10/137 (7%)

Query: 1270 IERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVH 1329
            ++ S+   ++ +E   E++  ++        ++ED  ++  P     L +  + EG  VH
Sbjct: 4207 LKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTP-----LVDTVSEEGDIVH 4261

Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED-SGVYTCQAT 1388
            L   +         V W+   K + +  +F+   + +   L +  V  ED  G Y C+A 
Sbjct: 4262 LTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 4317

Query: 1389 NQLGEAVTSCALRVIAK 1405
            N  G+  TS  L V+ +
Sbjct: 4318 NDSGKTATSAKLTVVKR 4334



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/143 (23%), Positives = 61/143 (42%), Gaps = 11/143 (7%)

Query: 3658 EPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDC 3717
            E +  S  +SGTE +  ++  + + E   I+++ P        + D +   EG  VH   
Sbjct: 4211 EEKEESSSESGTEEVATVK--IQEAEGGLIKEDGP---MIHTPLVDTVS-EEGDIVHLTT 4264

Query: 3718 RVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD-AGEYTCRATNKW 3776
             +    +    ++W+   +   +  +   L D     L ID +   D  GEY C A N  
Sbjct: 4265 SITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDS 4320

Query: 3777 GSATTTAKITCSAKRDIVLESQL 3799
            G   T+AK+T   +   V++ ++
Sbjct: 4321 GKTATSAKLTVVKRAAPVIKRKI 4343



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAED-SGVYTVVARNAAGEAQLSASMTV 1135
            V WYF  K + S  + +   D     L I  V  ED  G Y   A N +G+   SA +TV
Sbjct: 4272 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331

Query: 1136 ETRSS 1140
              R++
Sbjct: 4332 VKRAA 4336



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/68 (29%), Positives = 34/68 (50%)

Query: 2667 EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            E ++ PN++ +WFK G  +    +        + +L I   +  D G YTCKA+N  G  
Sbjct: 4359 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 4418

Query: 2727 VSTASIKI 2734
              TA++ +
Sbjct: 4419 SCTATLTV 4426



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 9/126 (7%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G SA +EC + P         W  +G  ++   ++R   D     L I+ V   D+GEYT
Sbjct: 4636 GSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 4692

Query: 1919 CKAINNLGQAVSSIRLNVQS-KESIIRDSQHESALEKIQ--YLEDDSRYKRAV---QDDS 1972
            C       +  S+ +L V+      ++  + E  + K Q  YL  +   +R V   +D  
Sbjct: 4693 CVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGK 4752

Query: 1973 FVVEKP 1978
             VVEKP
Sbjct: 4753 IVVEKP 4758



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 8/122 (6%)

Query: 2336 AKGSIISESQRPEGLEKIRELE-SAEPFKRPEIPEPVTRQRPV-FTQPLQNIDNIQEGQT 2393
            ++G + + + R   LE   E++ +A+ FK         ++ PV FT+PL++   ++EG T
Sbjct: 5748 SEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHA--NLFVKEPPVEFTKPLED-QTVEEGAT 5804

Query: 2394 AHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453
            A  +C    V     KV+WF+N   I  S +     D     + I     ED   Y C A
Sbjct: 5805 AVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861

Query: 2454 SN 2455
             +
Sbjct: 5862 KD 5863



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 61/307 (19%), Positives = 115/307 (37%), Gaps = 47/307 (15%)

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
            ++++++E  +  F  +++     +  WF+N + + +S+K+ I+      TLR+R+    D
Sbjct: 6150 KDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDD 6208

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
              +Y +   N  G         V+S     V+++  + +   +  ET E+          
Sbjct: 6209 QANYNVSLTNHRG-------ENVKSAANLIVEEEDLRIVEPLKDIETMEK---------- 6251

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
                          K   F C+V  R    + W  N  ++  D      V++   H L I
Sbjct: 6252 --------------KSVTFWCKV-NRLNVTLKWTKNGEEVPFDNRVSYRVDKY-KHMLTI 6295

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             +    D G     A    G+      L +IE       +FVE      V E +  V + 
Sbjct: 6296 KDCGFPDEGEYIVTA----GQDKSVAELLIIE----APTEFVEHLEDQTVTEFDDAVFSC 6347

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            + +      + W ++G  I    + +   DG    L I   +  D   Y C  ++     
Sbjct: 6348 Q-LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVED----R 6402

Query: 573  ATRARLY 579
             +RARL+
Sbjct: 6403 KSRARLF 6409



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 2/79 (2%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG+           P P   V W+ +GK +++  R    ND   A L++      D+G Y
Sbjct: 7903 EGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 7960

Query: 1918 TCKAINNLGQAVSSIRLNV 1936
            T    N LG A +SI + V
Sbjct: 7961 TITLENKLGSATASINVKV 7979



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/131 (23%), Positives = 52/131 (39%), Gaps = 5/131 (3%)

Query: 3657  LEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRF--TVEIKDNIDVPEGGPVH 3714
             LE +    F++   +   +       + +TI  E   PPR   +V +K  + V  G  V 
Sbjct: 12759 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-PPRIDLSVAMKSLLTVKAGTNVC 12817

Query: 3715  FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
              D  V   G P   + W  +G        +          L++  +  +D+G+YT  A N
Sbjct: 12818 LDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 12875

Query: 3775  KWGSATTTAKI 3785
               GS + T K+
Sbjct: 12876 SSGSKSATIKL 12886



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/84 (23%), Positives = 36/84 (42%)

Query: 4730  IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
             + V  G        +  K  PT+ W ++G L+      +M  + N   L + +   +D+G
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12867

Query: 4790  TFTCRATTAAGQVETSAKLVVKSK 4813
              +T  A  ++G    + KL V  K
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDK 12891



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 17/71 (23%), Positives = 33/71 (46%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             +  + G P  ++    G P P++TW+ + + +     + I T    +TL +  +   D+ 
Sbjct: 22160 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22219

Query: 560   WYQCTAQNVAG 570
              Y  T +N AG
Sbjct: 22220 RYFLTLENTAG 22230



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/79 (26%), Positives = 32/79 (40%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
             +  G  +     + GKP P + W KGDK +   +   +  T    T  I      D G Y
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKY 22621

Query: 4694  KCVAYNSAGRVTVAAKLKV 4712
                  N++G   V+  +KV
Sbjct: 22622 TLTVKNASGTKAVSVMVKV 22640



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 8/116 (6%)

Query: 48    MTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR 107
             M+   ES  + +P+   R   P   + + + K      G + +    + G P PV++W++
Sbjct: 22928 MSEYSESIAEIEPVE--RIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK 22985

Query: 108   KKAPLVECNKYSMRYNEQTGDVSLLI-KQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
             +   L      S    + T   SLLI  ++   D G+YT  A NQ G+   +V ++
Sbjct: 22986 QGIDLA-----SRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23036



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 15/42 (35%), Positives = 21/42 (50%)

Query: 4110  PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
             PP   +LP  ++++EG+     C  TG P P V W   G  I
Sbjct: 26831 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 26872



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 16/179 (8%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  P   T++ KDI +  E     +E ++   G   +  +W  NG  I+++ + +     
Sbjct: 2919 TVTPIMITSMLKDI-NAEEKDTITFEVTVNYEG---ISYKWLKNGVEIKSTDKCQMRTKK 2974

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L I      D+  Y+  A      A + V+   ++        F  HI++I+ L+ 
Sbjct: 2975 LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIE--------FRKHIKDIKVLEK 3026

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             + A FEC V    +PD+ ++W  + Q ++ + RIK   +     L I  T+  D+G+Y
Sbjct: 3027 -KRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKY 3081



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 85/408 (20%), Positives = 153/408 (37%), Gaps = 38/408 (9%)

Query: 1800 LFVQSKASLQLESQHESALQKIQQLEDSSRYQ-----RREDVEVAVNQA-PRFITQLNGP 1853
            L      S+Q E +  S   K   ++D+S+ +        + ++ V +  P F  +L   
Sbjct: 5471 LHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDY 5530

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
            T + E      +C I     P   V+W+ +GK ++         D     L +      D
Sbjct: 5531 TGV-EKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKTDGKKRMLILKKALKSD 5586

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQSKE-SIIRDSQHESALEKIQYLEDDS-RYKRAVQDD 1971
             G+YTC    + G   +S +L+++ +E  ++R       L  ++ +E ++ R++  + +D
Sbjct: 5587 IGQYTC----DCGTDKTSGKLDIEDREIKLVRP------LHSVEVMETETARFETEISED 5636

Query: 1972 SFVVEKPQFGKPI---KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
                     G+ +    + E+ E   +H         D T  V++           R K 
Sbjct: 5637 DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKP 5696

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNA--------VGEAVTTSSVKVDAKSG-LYLDT 2079
                    L  +   A +T T+ C+ +           G+ +  S   V    G ++  T
Sbjct: 5697 RVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLT 5756

Query: 2080 LDEQRLKKIQELEKYERP-KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPIND 2138
            L + +L+   E++   +  K        + PV  T     + ++EG  A  EC V   N 
Sbjct: 5757 LRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSREN- 5815

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186
                + WF NG +I    +Y    D     L I     ED  TY C A
Sbjct: 5816 --AKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 18/78 (23%), Positives = 41/78 (52%), Gaps = 1/78 (1%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P +I + P++     GAD  F  +L+ + +  V W +N   ++  +KH++++      L+
Sbjct: 6414 PVEIIRPPQDILEAPGADVVFLAELNKD-KVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQ 6472

Query: 325  VRNTQKSDSGHYTLLAEN 342
            + + +  D G Y  +A++
Sbjct: 6473 ICDIKPRDQGEYRFIAKD 6490



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 3/91 (3%)

Query: 2645 TTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            T  L+++D +V EG+   L   V  R  P   + W K+G  +    RL    D     L 
Sbjct: 7891 TIDLETHDIIVIEGEK--LSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLE 7948

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +      D+GIYT    N LG A ++ ++K+
Sbjct: 7949 VPKSVRADAGIYTITLENKLGSATASINVKV 7979



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 7/95 (7%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK-------DGVPIIPNPELRIHTDG 543
            P  ++    + V EG  V + A+  G P P +TW K       +  P++ +  +      
Sbjct: 9620 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 9679

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               TL IP+++ SD   Y  TA N  G+ +   RL
Sbjct: 9680 DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9714



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/84 (26%), Positives = 36/84 (42%)

Query: 4727  LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
             +  +VV  G   +F   I     PT +W  +G+ I     + +  +  ++VL I N    
Sbjct: 11020 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11079

Query: 4787  DTGTFTCRATTAAGQVETSAKLVV 4810
             DTG +    + AAG    +  L V
Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 2/86 (2%)

Query: 3840  TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899
             TV   + +R   RV+ + +P   I W + GK+L    R   + D+  V L I      D 
Sbjct: 11422 TVRVGQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADH 11479

Query: 3900  GEYICRAVNDFGEDFTKATISCKKLP 3925
             G+YI  A N  G     A ++    P
Sbjct: 11480 GKYIISAKNSSGHAQGSAIVNVLDRP 11505



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 502   VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
             VR G P+ L A   G P P++TW+K G+  +   + ++      + L IP +   D+  Y
Sbjct: 12121 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVR-KGQVDLVDTMAFLVIPNSTRDDSGKY 12179

Query: 562   QCTAQNVAGSTA 573
               T  N AG  A
Sbjct: 12180 SLTLVNPAGEKA 12191



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 2/87 (2%)

Query: 776   LQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHL 835
             ++ L  ++ G N   +A  T    P   V W KDG  +  +  I         +L +  +
Sbjct: 12804 MKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSV 12861

Query: 836   RAEDAGSYTVRAVNKLGEAISTASIRV 862
               +D+G YT+ A N  G   +T  ++V
Sbjct: 12862 NRKDSGDYTITAENSSGSKSATIKLKV 12888



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 4/60 (6%)

Query: 287   VQLSGNPRPRVTWFKN-GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             V + G P P V W ++ G+ L   +K  I +  ++T L V N  + DSG Y L  EN +G
Sbjct: 15385 VPIKGRPDPEVKWARDHGESL---DKASIESASSYTLLIVGNVNRFDSGKYILTVENSSG 15441



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/69 (30%), Positives = 34/69 (49%)

Query: 4525  VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
             V +G+  RL+  V G     + WL+  K+++   R +I   D    L++ +A   D G+Y
Sbjct: 17140 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17199

Query: 4585  ECVAINSAG 4593
                A N AG
Sbjct: 17200 ILRASNVAG 17208



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 35/127 (27%), Positives = 50/127 (39%), Gaps = 8/127 (6%)

Query: 2629  VPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
             VP +  D  +Q  P       +Y  +  G+ + +E  V  R  PN  I W K+G  L   
Sbjct: 17804 VPVIAKDLTIQ--PSLKLPFNTYS-IQAGEDLKIEIPVIGRPRPN--ISWVKDGEPLKQT 17858

Query: 2689  ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPD 2748
              R+          L I     DD G YT  ATN  G A    S+ + ++    G  + P 
Sbjct: 17859 TRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKP---GPPVGPV 17915

Query: 2749  SLDRIGA 2755
               D + A
Sbjct: 17916 RFDEVSA 17922



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 2/98 (2%)

Query: 1977  KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
             +P    P     +  G  + +E  +  +  P   + W  +G P++Q  R           
Sbjct: 17814 QPSLKLPFNTYSIQAGEDLKIEIPV--IGRPRPNISWVKDGEPLKQTTRVNVEETATSTV 17871

Query: 2037  LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074
             L I     +D G Y   ATN+ G A    SV V  K G
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG 17909



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 2/82 (2%)

Query: 1055  IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
             I  G+S   +A V+ +      V W+ +G +I     ++  +  G  +L +     +  G
Sbjct: 21473 IKSGESLRIKALVQGRP--VPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRG 21530

Query: 1115  VYTVVARNAAGEAQLSASMTVE 1136
             VYTV A+NA+G A+    + V+
Sbjct: 21531 VYTVEAKNASGSAKAEIKVKVQ 21552



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 2/107 (1%)

Query: 59    QPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNK 117
             +PIT         P F++  +N       NA    K+ G+P P+V W R+ K  + +  K
Sbjct: 24418 EPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 24477

Query: 118   YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
             Y ++   + G   L+I  +   D   Y   A NQ G    +  ++ E
Sbjct: 24478 YRIQ-EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 72    PIFEQIFKNARFAQGGNAKFEGKLRG-NPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
             P+  QI  +A   +GG+ K+  K+   + +  V+W      L    KY + Y +  G   
Sbjct: 25072 PVSGQIM-HAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED--GVAI 25128

Query: 131   LLIKQIGPGDEGEYTCTARNQYGE 154
             L +K I   D+G Y C   N YGE
Sbjct: 25129 LYVKDITKLDDGTYRCKVVNDYGE 25152



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 489   VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG--GAS 546
             + PK     S +++ EG+ + +     G PTP +TW   G  I    + R H +     +
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 26889

Query: 547   TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             TL I   +  D   Y  +  N  GS +    ++
Sbjct: 26890 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIH 26922



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 4512  VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
             +PP       ++++  G+++ +    TG    +V W   G+K+  Q   R  I   D   
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 26889

Query: 4570  TLLILEAYPQDSGKYECVAINSAG 4593
             TL+I++   QD G Y     N  G
Sbjct: 26890 TLIIMDVQKQDGGLYTLSLGNEFG 26913



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 6/113 (5%)

Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALD 3756
            FT E++D +   +     F+C      +P +++ W+ +G     G +    +D     L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ---LPQGMSGE 3806
            I  I   DA +Y+C         TT   I   A  + V E Q   +P+  SGE
Sbjct: 2187 ILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGE 2239



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 2776 FISHLNNIVCKEGDNIH-FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            F   L ++V KE D +  FEC      +P +K++W+ +   +  G +Y+   D     L 
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETS---EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLS 2186

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTS 2860
            I      D+  Y+C     +   TT+
Sbjct: 2187 ILTIDTSDAEDYSCVLVEDENVKTTA 2212



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 6/118 (5%)

Query: 1692 EDTSKYQRHSAQDEVITQ-APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            E+ +  +   A+  +I +  P+   P+ D    E    H    +    +    V W    
Sbjct: 4223 EEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFEN 4278

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPED-SGTYTCRAINELGEAVTSSTLFVQSKAS 1807
              + +  +   + D     L +  VN ED  G Y C A+N+ G+  TS+ L V  +A+
Sbjct: 4279 KLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 4336



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P    PL    + EG  +H  T I    +    + W    + + +  +F  +      +L
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTL 4298

Query: 697  DMLSLNIQD-SGEYTCRAVSATGVAETKAVLHVTPRA 732
             +  +N +D  GEY C A++ +G   T A L V  RA
Sbjct: 4299 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 4335



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 1/116 (0%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF-EARVEPQSDLTMTVEW 1079
            +Y+ +A   S +T    K+T   R    +K   + +E    H  +   E QS   +  +W
Sbjct: 4311 EYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQW 4370

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +  G++I  +++          +L+I   +  D G YT  A N  G    +A++TV
Sbjct: 4371 FKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 5/86 (5%)

Query: 3826 VSTPP-KFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP +F   ++  TVEE      EC V  +E+ K  ++W++NG  +    +Y  V D 
Sbjct: 5783 VKEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAK--VKWFKNGTEILKSKKYEIVADG 5839

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDF 3910
                L I     ED   Y C A  DF
Sbjct: 5840 RVRKLVIHDCTPEDIKTYTCDA-KDF 5864



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 60/258 (23%), Positives = 104/258 (40%), Gaps = 31/258 (12%)

Query: 89   AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCT 147
            A+FE +L       V W +  A + +  KY +      G V +L I +    DE EY+C 
Sbjct: 5894 ARFECEL-SRENAKVKWFKDGAEIKKGKKYDII---SKGAVRILVINKCLLDDEAEYSCE 5949

Query: 148  ARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKV 207
             R      + +V ++ E                 VSET       T     E S+   +V
Sbjct: 5950 VRTARTSGMLTV-LEEEAVFTKNLANI------EVSET------DTIKLVCEVSKPGAEV 5996

Query: 208  AYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEI--DRSLGPVSP 265
             +  G      D+  ++T  Y +L E   R  + +    E     +  +   R+ G V  
Sbjct: 5997 IWYKG------DEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKV 6050

Query: 266  PKIA----QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
             ++A     KP+N ++ EG  A+F   +S    P V W ++ + L + +K+++I      
Sbjct: 6051 HELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR 6109

Query: 322  TLRVRNTQKSDSGHYTLL 339
             L V++    D G Y ++
Sbjct: 6110 VLVVKDATLQDMGTYVVM 6127



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+ HL +    E D+  F C +  SR+    ++W+ N + +  G +YK   D S   L I
Sbjct: 6328 FVEHLEDQTVTEFDDAVFSCQL--SREKA-NVKWYRNGREIKEGKKYKFEKDGSIHRLII 6384

Query: 2836 THTYEEDSGIYTCKATNSKGSA 2857
                 +D   Y C   + K  A
Sbjct: 6385 KDCRLDDECEYACGVEDRKSRA 6406



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 10/101 (9%)

Query: 2947 WYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            W F  KVLE G R K+ +   +  L +      D GIYT K  N+        T+     
Sbjct: 6931 WCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR------VKTISGEID 6984

Query: 3007 DNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRP 3047
             N+I R   PK  +    I      L  EP   PDDD G P
Sbjct: 6985 VNVIARPSAPKELK-FGDITKDSVHLTWEP---PDDDGGSP 7021



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            ++I+  EG+ +           PT  + W  + K + +  R    +D     L++  +  
Sbjct: 7897 HDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVR 7954

Query: 2841 EDSGIYTCKATNSKGSATTSGSLRCTG 2867
             D+GIYT    N  GSAT S +++  G
Sbjct: 7955 ADAGIYTITLENKLGSATASINVKVIG 7981



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 4613 KPQTKAANAPPEIIE---PLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
            +P T A    P  +E    +K  I +  G+ +     + G+P+PT  W K +  +   + 
Sbjct: 8594 QPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRV 8653

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
              +     +  L I +A  +D G Y   A NS G    AA+++V
Sbjct: 8654 V-IDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8696



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/72 (25%), Positives = 30/72 (41%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             RF     G P+P  KW  +   IK    + + T +  S+L I+     D+  +     N 
Sbjct: 11032 RFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA 11091

Query: 4489  GGTAKCSANLVV 4500
              G+   + +L V
Sbjct: 11092 AGSKTVAVHLTV 11103



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 263   VSPPKIAQKPRNSKL---QEGADAQFQVQLSGNPRPRVTWFKNG-QRLINSNKHEIITTH 318
             + PP+I       KL   + G   +    + G P P+VTW K G   ++   + +++ T 
Sbjct: 12104 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTM 12163

Query: 319   NHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L + N+ + DSG Y+L   NP G
Sbjct: 12164 --AFLVIPNSTRDDSGKYSLTLVNPAG 12188



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 69/327 (21%), Positives = 120/327 (36%), Gaps = 22/327 (6%)

Query: 2933  GQVEPKNDPDLKIEWYFNGKVLEQGSRF-KLTSDFGFVTLDLVDVYERDSGIYTCKAYNK 2991
             G  EP   P +  ++ F      + +R  K+  D  FV  D  D    D G        +
Sbjct: 12576 GISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPD---SDGGSPIIGYLIE 12632

Query: 2992  RGEAFTSSTVYCTSKDNLIERTQHPKG--TEGLE---KIQNLEDSLRKEPGQQPDDDTGR 3046
             R E   +S ++  + D L+  T++P     EGLE   +I  L  +    P +  +  T R
Sbjct: 12633 RKER--NSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR 12690

Query: 3047  PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
              P       +++D+++  ++   A     G  S +I +F     +     +R   A   +
Sbjct: 12691 MPVDPPGKPEVIDVTKSTVSLIWARPKHDGG-SKIIGYFVEACKLPGDKWVRCNTAPHQI 12749

Query: 3107  VLE-ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK----SKGQKPRFTTHI--QNIE 3159
               E    T   +   Y  RA  +     IS   E  D     ++   PR    +  +++ 
Sbjct: 12750 PQEEYTATGLEEKAQYQFRAIARTA-VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12808

Query: 3160  GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
              +K G +   + TV     P   + W  +G  ++ +  IK         L++      DS
Sbjct: 12809 TVKAGTNVCLDATVF--GKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12866

Query: 3220  GEYVCRAYNKYGEDFTRATINCYGKGG 3246
             G+Y   A N  G       +    K G
Sbjct: 12867 GDYTITAENSSGSKSATIKLKVLDKPG 12893



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 4/103 (3%)

Query: 904   ESTQKPEFKTPIK--DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
             +  + P+ K  +K  D + +K G     EA +   G     +EW KDG+ +E ++++   
Sbjct: 14957 DDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS--GRPPPTMEWSKDGKELEGTAKLEIK 15014

Query: 962   FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                    L  K  T  D+G YT  A N  G A    N+ ++ +
Sbjct: 15015 IADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 15057



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/106 (21%), Positives = 47/106 (44%), Gaps = 4/106 (3%)

Query: 380   EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
             ++ +E+   ++ P+F        V  G+  R +  V G+P P + W   D++I +    +
Sbjct: 17120 KDEVELPRISMDPKFRDTIV---VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCE 17176

Query: 440   ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             I  N      L++ +    D G     A N +G  +F   + V+++
Sbjct: 17177 I-KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR 17221



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/105 (23%), Positives = 39/105 (37%), Gaps = 4/105 (3%)

Query: 902   VPESTQKPEFKTPIK--DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT 959
             V +  + P     +K  D I +K G      A +   G     + W KDG  +E  +R  
Sbjct: 19283 VKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIA--GRPLPVISWAKDGIEIEERARTE 19340

Query: 960   TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                   +  LT+K     D G Y     N  G  + + N  ++ K
Sbjct: 19341 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 2/92 (2%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             EF     D + IK G     +A ++  G    RV W KDG  +E    +      G  +L
Sbjct: 21462 EFGPEYFDGLIIKSGESLRIKALVQ--GRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSL 21519

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              ++  T    G YT  A NA G A     + +
Sbjct: 21520 FVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 502   VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
             VR G  + L     G PTP   W K    +    +  IHT    STL +     +DA  Y
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD--IHTTDSFSTLTVENCNRNDAGKY 21929

Query: 562   QCTAQNVAGS 571
               T +N +GS
Sbjct: 21930 TLTVENNSGS 21939



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%)

Query: 412   DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNK 470
             D  V G+P P++ W   D+++  D   K+ +  +G  A  +I     SDSG  T   +N 
Sbjct: 22571 DAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 22628

Query: 471   SGETAFQCRLNVIE 484
             SG  A    + V++
Sbjct: 22629 SGTKAVSVMVKVLD 22642



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 2648  LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             LK    +  G  + L   V  R  P   I W K G+ L + A + +T  + L  L ++ +
Sbjct: 22955 LKKTVTIRAGASLRLMVSVSGRPPP--VITWSKQGIDLASRAIIDTTESYSL--LIVDKV 23010

Query: 2708  RNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                D+G YT +A N  G+  +T  +K+ D
Sbjct: 23011 NRYDAGKYTIEAENQSGKKSATVLVKVYD 23039



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 643   LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
             +K VT   G       +I  VG P   I+W + G+ +  S ++         +L +++  
Sbjct: 24042 MKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEE 24099

Query: 703   IQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
              +D G YTC A +  G  ET  K +L  TP+
Sbjct: 24100 QEDEGVYTCIATNEVGEVETSSKLLLQATPQ 24130



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 785   GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
             G  A    Q+  V  P   ++WY+ G+ +  S +     +    +L +M    ED G YT
Sbjct: 24050 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 845   VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRY 880
               A N++GE + T+S ++  ++T     G P + +Y
Sbjct: 24108 CIATNEVGE-VETSS-KLLLQATPQFHPGYPLKEKY 24141



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 11/120 (9%)

Query: 2640  QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT-GARLK-STFDF 2697
             QAP F   L++ +   +  +  L  +V     P +K  W++ G  +   G + +   F  
Sbjct: 24429 QAPHFKEELRNLNVRYQS-NATLVCKVTGHPKPIVK--WYRQGKEIIADGLKYRIQEFKG 24485

Query: 2698  GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLH-PDSLDRIGAL 2756
             G   L I S+ +DD+ +Y  +ATN  G    TAS+++E     +   +H P +L+ +GA+
Sbjct: 24486 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-----VPAKIHLPKTLEGMGAV 24540



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 3/81 (3%)

Query: 2656  EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD-FGLVTLSINSLRNDDSGI 2714
             EGQ V  E +V     P LK  W K+G  L+ G  ++   +      L I     +D+G 
Sbjct: 25311 EGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGY 25368

Query: 2715  YTCKATNLLGEAVSTASIKIE 2735
             Y   ATN  G     A +++E
Sbjct: 25369 YRVTATNTAGSTSCQAHLQVE 25389



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 8/120 (6%)

Query: 355   VESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCR 414
             V+SP  S+ +   S   T    RE  + + +S      QF+K    +++   K+T   C 
Sbjct: 26188 VKSPEPSHPKAV-SPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIA--KLT---CV 26241

Query: 415   VTGRPY--PEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
             V        EVTW+ + ++++++ + +   +  G + L I N+T SD G   C    + G
Sbjct: 26242 VESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGG 26301



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 11/147 (7%)

Query: 3670 ESIQKLEETLHKREEITIEDEKPN-----PPRFTVEIKDNID---VPEGGPVHFDCRVEP 3721
            E  ++ ++ L +  +ITI   KP+     P     +I + I    V +G   HF  RV  
Sbjct: 1998 ELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHF--RVRV 2055

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
            VG P    +W+ NG       R++    +     L I  + A D+     +A N  G  +
Sbjct: 2056 VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETS 2115

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEK 3807
            + A +   AK+ I    +L   ++ EK
Sbjct: 2116 SHAFLLVQAKQLITFTQELQDVVAKEK 2142



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F K  +D  V E K   F+C V+  P   V W  +D++++     KI   E   H L+I
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQ-KEKYVHRLLI 3070

Query: 453  TNVTLSDSGVVTCVA-RNKSGETAF----QCRLNVIEKEQVVAPK 492
             +  +SD+G  T VA  N S    F      R+  I+KE  V  K
Sbjct: 3071 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 3115



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 3557 PPEFTTTPSDLILSEN----SSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            P +F     D+IL+E+    SSA FEC + P   S+    W  +G  +    + + I D 
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADG 4673

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
                L I  V   DAG YTC     + E T + KL V+
Sbjct: 4674 KDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 4711



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 1/87 (1%)

Query: 4511  IVPPSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
             + PP+  L  ++ + +  G+   L  + +G     V W K+   V  D R  I     T 
Sbjct: 10318 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10377

Query: 4570  TLLILEAYPQDSGKYECVAINSAGEAR 4596
              L  ++A   DSGKY  V  NS G  +
Sbjct: 10378 ALEKIKAKRSDSGKYCVVVENSTGSRK 10404



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT-FFNFGYVA 968
             E    + + + +K G    F A +  +   T +  W  DG  ++     T    NF  V 
Sbjct: 11014 ELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEHYTVETDNFSSV- 11070

Query: 969   LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             LTIK+    D G Y     NA G  T + +LT++
Sbjct: 11071 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVL 11104



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 381   ERIEISEKALAPQF-VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD-DYNH 438
             E + + E    P   +K+     V  G   R +  V G+P+PEV W   D+   D   + 
Sbjct: 11693 EEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAW-TKDKDATDLTRSP 11751

Query: 439   KILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             ++ ++  + +    +T    SD G     A N +G       +NV++K
Sbjct: 11752 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDK 11799



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/66 (28%), Positives = 33/66 (50%)

Query: 1874  PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             P   V W  +G +L+     + +       L++ +V  +DSG+YT  A N+ G   ++I+
Sbjct: 12826 PMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 12885

Query: 1934  LNVQSK 1939
             L V  K
Sbjct: 12886 LKVLDK 12891



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 2/81 (2%)

Query: 85    QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
             +  N + +  ++G P P VSW + + PL    + S+       + +L++      D G+Y
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV--ESSAVNTTLIVYDCQKSDAGKY 13556

Query: 145   TCTARNQYGEAICSVYIQPEG 165
             T T +N  G    ++ I+  G
Sbjct: 13557 TITLKNVAGTKEGTISIKVVG 13577



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 1/88 (1%)

Query: 915   IKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSV 974
             IKD ++IK G      A +  +G    +  W K G+ +  S             LTIK  
Sbjct: 13887 IKDGLTIKAGDTIVLNA-ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYA 13945

Query: 975   TVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             T  DAG YT  A N  G       +T++
Sbjct: 13946 TRKDAGEYTITATNPFGTKVEHVKVTVL 13973



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%)

Query: 4508  RGGIVPPSFTLTAQ---NVNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKIL 4563
             R  + PP  ++  +    + V +G+  ++D  + G KPI  + W+K  +++    R +I 
Sbjct: 16038 RDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG-KPIPTIQWIKGDQELSNTARLEIK 16096

Query: 4564  EEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
               D   +L + +A   DSG Y   A N AGE
Sbjct: 16097 STDFATSLSVKDAVRVDSGNYILKAKNVAGE 16127



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/72 (31%), Positives = 33/72 (45%)

Query: 499   TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             T+ V  GE   ++A   G P P I W K    +     L I +   A++L +  A   D+
Sbjct: 16055 TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 16114

Query: 559   AWYQCTAQNVAG 570
               Y   A+NVAG
Sbjct: 16115 GNYILKAKNVAG 16126



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 3/86 (3%)

Query: 263   VSPPKIAQKPR---NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
             V  P+I+  P+      +  G   + +  + G P P + W +  + +  S + EI  T  
Sbjct: 17123 VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17182

Query: 320   HTTLRVRNTQKSDSGHYTLLAENPNG 345
                L V++  + D G Y L A N  G
Sbjct: 17183 KALLIVKDAIRIDGGQYILRASNVAG 17208



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 2/56 (3%)

Query: 2404  GDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             G P   +EW R +K IE+S+R   K  DF  + +    +R  D G Y+ RASN+ G
Sbjct: 17154 GKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIR-IDGGQYILRASNVAG 17208



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/68 (32%), Positives = 28/68 (41%)

Query: 500   LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             + VR G  V L     G P P I+W KDG+P+  +  +R        TL I  AK     
Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21135

Query: 560   WYQCTAQN 567
              Y     N
Sbjct: 21136 KYTVILDN 21143



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/98 (23%), Positives = 41/98 (41%), Gaps = 5/98 (5%)

Query: 68    EPSPPIFE---QIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
             E  PPI E   + F       G + + +  ++G P P V+W +    + +  + +M    
Sbjct: 21455 ENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK--RMNMEITN 21512

Query: 125   QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
               G  SL ++       G YT  A+N  G A   + ++
Sbjct: 21513 VLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 21550



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             +  G+++ ++  ++  G P  RV WF +G  +      +     G  +L +  AT    G
Sbjct: 21473 IKSGESLRIKALVQ--GRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRG 21530

Query: 1249  EYTVRAVNHLGSAHTSAIVRV 1269
              YTV A N  GSA     V+V
Sbjct: 21531 VYTVEAKNASGSAKAEIKVKV 21551



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 6/78 (7%)

Query: 85    QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
             QGG  +    ++G P P+  WT++     + +K +M    +T    L+IK+   GD G Y
Sbjct: 23653 QGGVIRLTIPIKGKPFPICKWTKEGQ---DISKRAMIATSET-HTELVIKEADRGDSGTY 23708

Query: 145   TCTARNQYGEAICSVYIQ 162
                  N+ G+   +VYI+
Sbjct: 23709 DLVLENKCGKK--AVYIK 23724



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 2/81 (2%)

Query: 3989  ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
             E  +  CQ+  VG P   ++W+  GK L+   ++    D     +       ED G Y C
Sbjct: 24051 EAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC 24108

Query: 4049  RATNLYGMDETKAVIKTTGKP 4069
              ATN  G  ET + +     P
Sbjct: 24109 IATNEVGEVETSSKLLLQATP 24129



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 2522  EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
             EGQ+  +   +   G+PS   EW+ N + + + S    +      +L+I +   +D+G Y
Sbjct: 26650 EGQNVLFTCEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 26707

Query: 2582  MCKAINRAG 2590
               KA N  G
Sbjct: 26708 TIKAKNFRG 26716



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/123 (22%), Positives = 57/123 (46%), Gaps = 4/123 (3%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            +++ ++ T  P FV R +S+  V +G  V  + ++  +   N  V+++++G  +     F
Sbjct: 94   ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIP--NPVVKFYRDGAEIQSSLDF 150

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEAGL 1552
            +   +    +L I +   EDSG Y+  A N VG    +  L  +   ++  + T+     
Sbjct: 151  QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVST 210

Query: 1553 EQI 1555
             QI
Sbjct: 211  AQI 213



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I  L ++ C E  N+ FE  +  S    + + W F +K +   ++YK         L + 
Sbjct: 2490 IRGLRDLTCTETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVL 2546

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            +  ++D G YT  A    G   TSG L   G
Sbjct: 2547 NMMKDDEGKYTFYA----GENMTSGKLTVAG 2573



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA-MNFGWVYPEDSGEYLCRA 4050
            KF C++     PN++ +WF  G+ +   ++ + I    Y++ +        D GEY C+A
Sbjct: 4355 KFTCEIQSA--PNVRFQWFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEYTCKA 4411

Query: 4051 TNLYGMDETKAVIKTT 4066
            +N YG     A +  T
Sbjct: 4412 SNEYGSVSCTATLTVT 4427



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+  T       + EG    LE +V      N K++WFKNG  +    + +   D 
Sbjct: 5783 VKEPPVEFTKPLEDQTVEEGATAVLECEVSRE---NAKVKWFKNGTEILKSKKYEIVADG 5839

Query: 2698 GLVTLSINSLRNDDSGIYTCKA 2719
             +  L I+    +D   YTC A
Sbjct: 5840 RVRKLVIHDCTPEDIKTYTCDA 5861



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            P +F+  ++D T + E   A F  +L         V+W+ NG+++  G +Y+   D  I 
Sbjct: 6325 PTEFVEHLEDQT-VTEFDDAVFSCQL---SREKANVKWYRNGREIKEGKKYKFEKDGSIH 6380

Query: 3341 ILDILYCYEENSGEYECVATNKLGR 3365
             L I  C  ++  EY C   ++  R
Sbjct: 6381 RLIIKDCRLDDECEYACGVEDRKSR 6405



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 17/69 (24%), Positives = 34/69 (49%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            ++ G   +    ++G P P++TW K    L    +  I      +T+ + ++++SD+G Y
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7264

Query: 337  TLLAENPNG 345
             + A N  G
Sbjct: 7265 IIEAVNVCG 7273



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P   +   DI V E +          V  P   V W ++G  ++AS+RLT  +D     L
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAHL 7947

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTS 1797
             +      D+G YT    N+LG A  S
Sbjct: 7948 EVPKSVRADAGIYTITLENKLGSATAS 7974



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 8/77 (10%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE---DSSRITK---THDFGYVSMTISHV 2441
            ++ G+  H    +   G P  K+EW +NE +IE   D+ +ITK   +       ++I   
Sbjct: 8913 VKAGEPVHIPADV--TGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 8970

Query: 2442 RDEDEGVYMCRASNLLG 2458
              ED+G Y   ASN LG
Sbjct: 8971 VREDKGTYTVTASNRLG 8987



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/108 (22%), Positives = 47/108 (43%), Gaps = 6/108 (5%)

Query: 381   ERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
             E + + ++   P+ +    + +++ +  G   R    + G P+P+VTW   DR       
Sbjct: 10708 EPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA--PTK 10765

Query: 438   HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
              +I V   G+  L I N    D G+ +    N +G      ++ V++K
Sbjct: 10766 ARIDVTPVGS-KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 10812



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 4512  VPPSFTLTAQN---VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568
             VPP   L+      + V +G  V LD  V G     V W K+G  ++P    K+  +   
Sbjct: 12794 VPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL 12853

Query: 4569  YTLLILEAYPQDSGKYECVAINSAG 4593
              TL +     +DSG Y   A NS+G
Sbjct: 12854 CTLELFSVNRKDSGDYTITAENSSG 12878



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 485   KEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             ++ V APK    V+   T+ ++ GE   L A   G P P + W KDG  +    +L I  
Sbjct: 14956 RDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI 15015

Query: 542   DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                ++ L    +   D+  Y  TA N  G
Sbjct: 15016 ADFSTNLVNKDSTRRDSGAYTLTATNPGG 15044



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/68 (29%), Positives = 30/68 (44%)

Query: 503   REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             + GE V +     G P P +TW+KD   +  +    I     +S L IP+   +D   Y 
Sbjct: 20787 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20846

Query: 563   CTAQNVAG 570
              T +N  G
Sbjct: 20847 LTIENGVG 20854



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/79 (25%), Positives = 39/79 (49%)

Query: 4525  VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
             + SG+ +R+   V G     V W K+G +++  +  +I    G+ +L + +A     G Y
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVY 21532

Query: 4585  ECVAINSAGEARCDAECVV 4603
                A N++G A+ + +  V
Sbjct: 21533 TVEAKNASGSAKAEIKVKV 21551



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/76 (26%), Positives = 32/76 (42%)

Query: 4637  GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
             G        I G+P P V W   +  +K +    ++ T D  TL + ++   D G Y   
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22224

Query: 4697  AYNSAGRVTVAAKLKV 4712
               N+AG  T +  + V
Sbjct: 22225 LENTAGVKTFSVTVVV 22240



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 1846 FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALD 1905
            F+ +L    ++ E  S   EC + P    N+  +WY N   L+S  +Y  ++  G   L 
Sbjct: 2223 FVKELQD-IEVPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2278

Query: 1906 ILTVYGEDSGEYT 1918
            +  V  ED GEY+
Sbjct: 2279 VKDVTKEDQGEYS 2291



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            +   TV ES+   FEC V    +P  + EW R+GK LP  +  R+  D     L I    
Sbjct: 2580 LTDQTVAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATK 2636

Query: 3896 AEDSGEY 3902
             +D GEY
Sbjct: 2637 LDDIGEY 2643



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            ++E Q A +EC +    +P+ + EW  +GK L   +  R+ +D     L I     +D G
Sbjct: 2585 VAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIG 2641

Query: 1916 EYTCKAINNLGQA---VSSIRLNVQSKESIIRDSQ 1947
            EYT K   +   A   V ++++    K   + ++Q
Sbjct: 2642 EYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQ 2676



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDI-LYCYEENSGEYECVATNKLGRDSTKANL 3372
            +V W++  K +P   +++   D     L I     E++ GEY C A N  G+ +T A L
Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4329



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 6/82 (7%)

Query: 1459 GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDLIAEDSGIY 1517
            G    F C+++     N++ +WFK G+ +    +   I    Y++ L+I+     D G Y
Sbjct: 4351 GHLAKFTCEIQSAP--NVRFQWFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEY 4407

Query: 1518 TCRAVNLVGTDEVSCRLTCRST 1539
            TC+A N  G+  VSC  T   T
Sbjct: 4408 TCKASNEYGS--VSCTATLTVT 4427



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 5/91 (5%)

Query: 626  PPGEEDRVYP----PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIE-WLKNGQSIE 680
            PP E    Y     P +F+  +K +   E   +      E +  P+  I  W+K+G +I 
Sbjct: 4603 PPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIR 4662

Query: 681  ASSRFTSIFRFGYISLDMLSLNIQDSGEYTC 711
             S +   I       L ++ + + D+GEYTC
Sbjct: 4663 ESPKHRFIADGKDRKLHIIDVQLSDAGEYTC 4693



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 2380 QPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTIS 2439
            +PL+++  +  G+TA FDC L     P   VEW+   K +E S ++    +    ++T+ 
Sbjct: 5703 RPLKDV-TVTAGETATFDCELSYEDIP---VEWYLKGKKLEPSDKVVPRSEGKVHTLTLR 5758

Query: 2440 HVRDEDEG 2447
             V+ ED G
Sbjct: 5759 DVKLEDAG 5766



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 5/79 (6%)

Query: 3557 PP--EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP  EF    +DL + E   A FEC L   N    +V+WF +G  +  G +   I+    
Sbjct: 5874 PPHVEFLRPLTDLQVREKEMARFECELSREN---AKVKWFKDGAEIKKGKKYDIISKGAV 5930

Query: 3615 VILEIGGVYQRDAGLYTCK 3633
             IL I      D   Y+C+
Sbjct: 5931 RILVINKCLLDDEAEYSCE 5949



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)

Query: 4113 FVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            F+S P  + + EGE A F C ++    P V W  +  T+ +G +Y +  DG
Sbjct: 6057 FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADG 6106



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 14/123 (11%)

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
            F   A N  G +K SA +   + +R      +PPS  L  + + V  G  V +  K+ G 
Sbjct: 9592 FRVKAVNAAGVSKPSATVGPCDCQRPD----MPPSIDLK-EFMEVEEGTNVNIVAKIKGV 9646

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEE--------DGTYTLLILEAYPQDSGKYECVAINSA 4592
                + W K   K +PD +  +L +        D T TL+I ++   D+G Y   A+N+ 
Sbjct: 9647 PFPTLTWFKAPPK-KPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9705

Query: 4593 GEA 4595
            G A
Sbjct: 9706 GTA 9708



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 2230  TRIEVE-EPKISPPRFVTELRGTTH--VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ 2286
             T I +E + K+ PP    +++      V  G T  F   +  V  P  +  +  +G  ++
Sbjct: 10998 TTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIK 11055

Query: 2287  SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             +   + +  D     L I++C+  D GEY +   NA G  T A+ +TV
Sbjct: 11056 TDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 5/105 (4%)

Query: 3685  ITIE-DEKPNPPRFTVEIK--DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
             I IE  EK  PP   +++K  + + V  G  V F   +  V  PT +  W  +G    T 
Sbjct: 11000 IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTD 11057

Query: 3742  SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
                    D     L I     RD GEY    +N  GS T    +T
Sbjct: 11058 EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 11102



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 3/86 (3%)

Query: 4511  IVPPSFTLTAQNVN---VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567
             +VPPS  L  + +    V +G  VR    + G       W  +G +++ D    +  ++ 
Sbjct: 11008 LVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNF 11067

Query: 4568  TYTLLILEAYPQDSGKYECVAINSAG 4593
             +  L I     +D+G+Y+    N+AG
Sbjct: 11068 SSVLTIKNCLRRDTGEYQITVSNAAG 11093



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/70 (27%), Positives = 29/70 (41%)

Query: 4001  GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
             G P   + W   GK L+ + R   I D   V +        D G+Y+  A N  G  +  
Sbjct: 11437 GRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 11496

Query: 4061  AVIKTTGKPG 4070
             A++    +PG
Sbjct: 11497 AIVNVLDRPG 11506



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/80 (26%), Positives = 30/80 (37%)

Query: 4633  IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             +  E         I GKP P+V W KG+  +       +  +A   TL + +    D G 
Sbjct: 13496 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13555

Query: 4693  YKCVAYNSAGRVTVAAKLKV 4712
             Y     N AG       +KV
Sbjct: 13556 YTITLKNVAGTKEGTISIKV 13575



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 2905  DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLT- 2963
             D E PK +  +       L  G+   LE  V  +  P +  EW  +GK LE  ++ ++  
Sbjct: 14958 DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTM--EWSKDGKELEGTAKLEIKI 15015

Query: 2964  SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
             +DF    L   D   RDSG YT  A N  G A
Sbjct: 15016 ADFS-TNLVNKDSTRRDSGAYTLTATNPGGFA 15046



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/69 (27%), Positives = 31/69 (44%)

Query: 1737  VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
             +G P   V W ++ VP++ + R+          L +K    ED G Y  +  N  GEA+ 
Sbjct: 15675 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIE 15734

Query: 1797  SSTLFVQSK 1805
             +  + V  K
Sbjct: 15735 TLNVIVLDK 15743



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/86 (20%), Positives = 34/86 (39%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             +  + EV   G P P I W ++  P+K +    +      + L I++   +D   +    
Sbjct: 16748 QDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITV 16807

Query: 4486  ENRGGTAKCSANLVVEEKRRQGRGGI 4511
              N  G    S  +V  +K    +G +
Sbjct: 16808 ANVVGQKTASIEIVTLDKPDPPKGPV 16833



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/61 (34%), Positives = 29/61 (47%)

Query: 2803  PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
             P   I W  + +PL   TR       +   L I    ++D G YT  ATNS G+AT + S
Sbjct: 17842 PRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLS 17901

Query: 2863  L 2863
             +
Sbjct: 17902 V 17902



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 16/78 (20%), Positives = 34/78 (43%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             EQ + +V F G P   + W ++   +K +    + +  T + L I++   ED   +    
Sbjct: 18913 EQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 18972

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N  G+      ++V ++
Sbjct: 18973 SNSAGSITVPITIIVLDR 18990



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 44/194 (22%), Positives = 73/194 (37%), Gaps = 15/194 (7%)

Query: 3042  DDTGRPPEFTTV-FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
             DD   P     V F+D++ +  G++    A +   G    VI W  +G  IE   R   +
Sbjct: 19285 DDVEPPRVMMDVKFRDVIVVKAGEVLKINADI--AGRPLPVISWAKDGIEIEERARTEII 19342

Query: 3101  YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   +L +      D+G Y     N  G   ++V  + +DK     P     I  +  
Sbjct: 19343 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKP--GPPAGPLEINGLTA 19400

Query: 3161  LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK-TVSDFGFVVLDIAYTQNHDS 3219
              K   S        P +D    I++YH  +  R ++ +  T+ +    +     T+    
Sbjct: 19401 EKCSLS-----WGRPQEDGGADIDYYH--RKKRETSHLAWTICEGELQMTSCKVTKLLKG 19453

Query: 3220  GEYVCR--AYNKYG 3231
              EY+ R    NKYG
Sbjct: 19454 NEYIFRVTGVNKYG 19467



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 2/99 (2%)

Query: 4606  PATKDKPKPQTKAANAPP-EIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
             P   ++P        AP  ++   L+  ++A+ G+ ++      G+P PTV W K +K +
Sbjct: 20756 PIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL 20815

Query: 4664  KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                  + +  T     L I +    D G Y     N  G
Sbjct: 20816 GSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/96 (28%), Positives = 38/96 (39%)

Query: 4522  NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
             +V   +G+ V++     G  P  V W K+ K +  D R  I   D +  L I +    D+
Sbjct: 20783 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDT 20842

Query: 4582  GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
             GKY     N  GE +     V  L       K Q K
Sbjct: 20843 GKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVK 20878



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 1832  RREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH 1891
             R E+V   V   P +   L     +  G+S   +  ++  P P  RV W+ +G  ++   
Sbjct: 21453 RDENVPPIVEFGPEYFDGLI----IKSGESLRIKALVQGRPVP--RVTWFKDGVEIEKRM 21506

Query: 1892  RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
                 +N  G  +L +     +  G YT +A N  G A + I++ VQ
Sbjct: 21507 NMEITNVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 2/72 (2%)

Query: 499   TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             T+ +R G  + L     G P P ITW K G+ +       I T    S L + +    DA
Sbjct: 22958 TVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTTESYSLLIVDKVNRYDA 23015

Query: 559   AWYQCTAQNVAG 570
               Y   A+N +G
Sbjct: 23016 GKYTIEAENQSG 23027



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 3/97 (3%)

Query: 905   STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
             S + P  +  +KD ++ K G  A    ++  +G     ++W + G+ +  S +     + 
Sbjct: 24032 SGEAPGIRKEMKD-VTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDG 24088

Query: 965   GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                 LT+ +    D G YTC A N +G+  TS+ L +
Sbjct: 24089 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLL 24125



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 1192  GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
             G+   L C++  +G P   ++W+  G+ +    ++K   D     L ++     D G YT
Sbjct: 24050 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 24107

Query: 1252  VRAVNHLGSAHTSA 1265
               A N +G   TS+
Sbjct: 24108 CIATNEVGEVETSS 24121



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 41/163 (25%), Positives = 65/163 (39%), Gaps = 10/163 (6%)

Query: 4357  GKEVHVAKQKQTQKEVVGDKE--ITRKITSTETTEIEHKAQTQERVVEGPVK-----PSK 4409
             GKE+     K   +E  G     I   +T  + T  + +A  Q   V G        P+K
Sbjct: 24468 GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 24527

Query: 4410  P--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTFSTKS 4466
                P   + M        E    ++ F G+P P+I W +    I N+  +Q I T S  S
Sbjct: 24528 IHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTS 24587

Query: 4467  ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
             ++    V  +D+  +   A+NR G  + +  L V +     RG
Sbjct: 24588 LVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG 24630



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/66 (27%), Positives = 33/66 (50%)

Query: 2936  EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
             E   +P  +IEW+ N   +   S   ++      +L++ +    DSG YT KA N RG+ 
Sbjct: 26659 EISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQC 26718

Query: 2996  FTSSTV 3001
               ++++
Sbjct: 26719 SATASL 26724



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V R  PV  + ++ ++ +  G  A F C +     P ++ +WF+  + I +S + +    
Sbjct: 4332 VKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSS 4388

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                S+ I   +  D G Y C+ASN  G
Sbjct: 4389 KYISSLEILRTQVVDCGEYTCKASNEYG 4416



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 4091 EASWQVTPEQVVEESKAR-CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            E S+Q    +     K +  P +F++    V V E + A+F C V+  PK    WL    
Sbjct: 5322 EVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQ 5380

Query: 4150 TIVNGSRYKLTYDGMYHFDIPKTRQYD 4176
             I    R++L  DG  H  + K+  ++
Sbjct: 5381 EITGDDRFELIKDGTKHSMVIKSAAFE 5407



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 6/79 (7%)

Query: 3281 PP--KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            PP  +F+  + D+ ++ E + A FE  L      + KV+WF +G ++  G +Y       
Sbjct: 5874 PPHVEFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGA 5929

Query: 3339 IVILDILYCYEENSGEYEC 3357
            + IL I  C  ++  EY C
Sbjct: 5930 VRILVINKCLLDDEAEYSC 5948



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 5/78 (6%)

Query: 3829 PP--KFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            PP  +F+  +    V E E  RFEC +  +E+ K  ++W+++G  +  G +Y  +     
Sbjct: 5874 PPHVEFLRPLTDLQVREKEMARFECELS-RENAK--VKWFKDGAEIKKGKKYDIISKGAV 5930

Query: 3887 VSLDILYVYAEDSGEYIC 3904
              L I     +D  EY C
Sbjct: 5931 RILVINKCLLDDEAEYSC 5948



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 3/91 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   +E  D I V EG  +        V  PT  + W  +G+      R+   ND     
Sbjct: 7890 PTIDLETHDII-VIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAH 7946

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L++      DAG YT    NK GSAT +  +
Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATASINV 7977



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 60   PITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR---KKAPLVECN 116
            P    RP  P P I  + F      +G N     K++G P P ++W +   KK    E  
Sbjct: 9611 PCDCQRPDMP-PSIDLKEFMEVE--EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPV 9667

Query: 117  KYSMRYNEQTGD--VSLLIKQIGPGDEGEYTCTARNQYGEA 155
             Y    N+   D   +L+I Q    D G YT TA N  G A
Sbjct: 9668 LYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTA 9708



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             E     +D I+++ G      AR++  G     + W K+G+ +    R+    +   V L
Sbjct: 11412 ELDVTCRDVITVRVGQTIRILARVK--GRPEPDITWTKEGKVLVREKRVDLIQDLPRVEL 11469

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
              IK     D G Y   A N+ G A  SA + ++ +
Sbjct: 11470 QIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDR 11504



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 3/91 (3%)

Query: 4634  VAEGQAIEFSCKIVGKPLPTVQWYKGDKL--IKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
             V  G  I     + GKP P V W K      +  S   ++   AD     +++A   D G
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11775

Query: 4692  DYKCVAYNSAGRVTVAAKLKV-TQPDQADNL 4721
              Y   A N+AG     A + V  +P    NL
Sbjct: 11776 KYVVTATNTAGSFVAYATVNVLDKPGPVRNL 11806



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 1189  VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
             V  G N+ L+  +   G P   V W  +G  +      K         L++      D+G
Sbjct: 12810 VKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12867

Query: 1249  EYTVRAVNHLGSAHTSAIVRVIER 1272
             +YT+ A N  GS   +  ++V+++
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDK 12891



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 6/79 (7%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS--LLIKQIGPGDEGE 143
             G N K E  + G P P V+W  KK    +  K + R N +T   S  L I +    D G 
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTW--KKGD--QILKQTQRVNFETTATSTILNINECVRSDSGP 14638

Query: 144   YTCTARNQYGEAICSVYIQ 162
             Y  TARN  GE    + IQ
Sbjct: 14639 YPLTARNIVGEVGDVITIQ 14657



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/78 (24%), Positives = 35/78 (44%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  R E +  G P P ++W ++   ++ +   +I      + L+ +     DS  +   A
Sbjct: 14980 EAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 15039

Query: 4486  ENRGGTAKCSANLVVEEK 4503
              N GG AK   N+ V ++
Sbjct: 15040 TNPGGFAKHIFNVKVLDR 15057



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 4425  HEQARFEVEFD--GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFA 4482
             H    F+V+ D  G+P+P I+W + +  + N+   +I +    + L ++     DS  + 
Sbjct: 16059 HAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYI 16118

Query: 4483  AVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
               A+N  G    + N+ V ++     G +V
Sbjct: 16119 LKAKNVAGERSVTVNVKVLDRPGPPEGPVV 16148



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 1/60 (1%)

Query: 3174  VPVDD-PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             VP+   P   I W  +G P++ +TRI          L I  T   D G+Y     N  G+
Sbjct: 16754 VPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 16813



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 2/72 (2%)

Query: 3716  DCRVE-PV-GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT 3773
             D ++E PV G P   I W  +G P    +RV+         L I      D G+YT  AT
Sbjct: 17831 DLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTAT 17890

Query: 3774  NKWGSATTTAKI 3785
             N  G+AT    +
Sbjct: 17891 NSAGTATENLSV 17902



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 4/60 (6%)

Query: 96    RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQYGE 154
             +G P P V+W + +  L    +YS+   E T   SLL I Q+   D G+Y  T  N  GE
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSI---ENTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20855



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
             V  G+       + GRP P  +WF    ++R+  + ++ V      A L I   T+ D+G
Sbjct: 23253 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRE--SERVTVETHTKVAKLTIRETTIRDTG 23310

Query: 462   VVTCVARNKSGETAFQCRLNVIEK 485
               T   +N +G T+   ++ +++K
Sbjct: 23311 EYTLELKNVTGTTSETIKVIILDK 23334



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 1/98 (1%)

Query: 4714  QPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
             QP   D+ P +T  +R   V  GQ  +F   + SK    ++W   G  + E+      + 
Sbjct: 25869 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 25928

Query: 4773  GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                  L I + + +D+GT+    T   G+    A L V
Sbjct: 25929 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 4/62 (6%)

Query: 2656  EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
             EGQ + L+A +   TD    ++W  NGV LT     +        TL+I    + D GI 
Sbjct: 26555 EGQRLVLKANIAGATD----VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGIL 26610

Query: 2716  TC 2717
             TC
Sbjct: 26611 TC 26612



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 50    TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
             TQ+ESS  +  + AG  G   PP  E +  +    +G          G PTP V+W+   
Sbjct: 26813 TQLESSTSKM-LKAGIRG--IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWS-CG 26868

Query: 110   APLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
                +   +    + E T D+ +L+I  +   D G YT +  N++G    +V I
Sbjct: 26869 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 26921



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 5/94 (5%)

Query: 3694  PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLNDFG 3751
             PP+    +  +I + EG  +   C     G+PT  + W   GR   +    R H  N   
Sbjct: 26831 PPKIEA-LPSDISIDEGKVLTVACAF--TGEPTPEVTWSCGGRKIHSQEQGRFHIENTDD 26887

Query: 3752  FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                L I  +  +D G YT    N++GS + T  I
Sbjct: 26888 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 26921



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 765  QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824
            Q  Q   F + LQD+   ++   A FE +    S+P ++V+WYKDG  +    +     +
Sbjct: 2123 QAKQLITFTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGMEVHEGDKYRMHSD 2179

Query: 825  FGYVSLNIMHLRAEDAGSYT 844
                 L+I+ +   DA  Y+
Sbjct: 2180 RKVHFLSILTIDTSDAEDYS 2199



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 7/143 (4%)

Query: 3559 EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILE 3618
            EF     D+ + E+ S   EC + P N   +  +W+HN   L +  +    +  G   L 
Sbjct: 2222 EFVKELQDIEVPESYSGELECIVSPEN---IEGKWYHNDVELKSNGKYTITSRRGRQNLT 2278

Query: 3619 IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEET 3678
            +  V + D G Y+       G+ T +CKL++K R   IL+         G     +++ +
Sbjct: 2279 VKDVTKEDQGEYSFVI---DGKKT-TCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS 2334

Query: 3679 LHKREEITIEDEKPNPPRFTVEI 3701
            L   E + ++D +   P   V I
Sbjct: 2335 LESVEGVWMKDGQEVQPSDRVHI 2357



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%)

Query: 4110 PPVFVSLP-DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PPV  + P +  TVEEG  A   C V+     +V W  NG  I+   +Y++  DG
Sbjct: 5786 PPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADG 5839



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF  +L NI   E D I   C V     P  ++ W+  ++ +    RY+   +     L 
Sbjct: 5967 VFTKNLANIEVSETDTIKLVCEVSK---PGAEVIWYKGDEEIIETGRYEILTEGRKRILV 6023

Query: 2835 ITHTYEEDSGIYTCKATNSK 2854
            I + + ED+G Y C+  +S+
Sbjct: 6024 IQNAHLEDAGNYNCRLPSSR 6043



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
            YP P     W F  KVL++G R +      +A L I      D G YT K  N +     
Sbjct: 6924 YPRPT--ATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 6981

Query: 1931 SIRLNVQSKES 1941
             I +NV ++ S
Sbjct: 6982 EIDVNVIARPS 6992



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 6/120 (5%)

Query: 2219 KIRQLEAQGHSTRIEVEEPKISP-PRFVTELRGTTH---VFEGKTAHFECQVEPVHDPNL 2274
            ++R + A G S   E+ E  ++  P     +   TH   V EG+          V  P  
Sbjct: 7862 RVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT- 7920

Query: 2275 RIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             + ++ +GK ++++ R  +  D     L++   V  DAG Y++   N LG  T++I++ V
Sbjct: 7921 -VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 1567 TDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKV---EWYHNNKPLKSG 1623
            +++ + V  + P C  ++ ++E  +      E+  IPV    + V    W+ + K +K+ 
Sbjct: 7875 SEISENVVAKDPDCKPTI-DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS 7933

Query: 1624 SRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
             R T  N+     L++   +  D+G YT    N LG A  S
Sbjct: 7934 DRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATAS 7974



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 4/102 (3%)

Query: 3684  EITIEDEKPNPPRFTVEI--KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
             E  I  +  +PP   +++  +D I V  G  +    RV+  G P   I W   G+     
Sbjct: 11398 ESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVK--GRPEPDITWTKEGKVLVRE 11455

Query: 3742  SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
              RV  + D   + L I      D G+Y   A N  G A  +A
Sbjct: 11456 KRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSA 11497



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 2/78 (2%)

Query: 1859  GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
             GQ+     R++  P+P+  + W   GKVL    R     D     L I      D G+Y 
Sbjct: 11426 GQTIRILARVKGRPEPD--ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 11483

Query: 1919  CKAINNLGQAVSSIRLNV 1936
               A N+ G A  S  +NV
Sbjct: 11484 ISAKNSSGHAQGSAIVNV 11501



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
             G   +   +++G P P ++WT++   LV   +  +   +    V L IK+    D G+Y 
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI--QDLPRVELQIKEAVRADHGKYI 11483

Query: 146   CTARNQYGEA 155
              +A+N  G A
Sbjct: 11484 ISAKNSSGHA 11493



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/126 (22%), Positives = 48/126 (38%)

Query: 3121  YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
             +  +  N+ G+++     E V K   QKP     +  +  +K G +   E  V     P+
Sbjct: 11676 FRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPE 11735

Query: 3181  MKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             +      +   +  S R+K  +        +   +  D G+YV  A N  G     AT+N
Sbjct: 11736 VAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVN 11795

Query: 3241  CYGKGG 3246
                K G
Sbjct: 11796 VLDKPG 11801



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/60 (30%), Positives = 29/60 (48%)

Query: 1076  TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             TV W  +G  +  A  I+         L++ SV  +DSG YT+ A N++G    +  + V
Sbjct: 12829 TVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 12888



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 4/85 (4%)

Query: 782   LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI-TSIFNFGYVSLNIMHLRAEDA 840
             L+ G     EA ++    PTM  EW KDG+ +  ++++   I +F    +N    R  D+
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTM--EWSKDGKELEGTAKLEIKIADFSTNLVNKDSTR-RDS 15032

Query: 841   GSYTVRAVNKLGEAISTASIRVAAR 865
             G+YT+ A N  G A    +++V  R
Sbjct: 15033 GAYTLTATNPGGFAKHIFNVKVLDR 15057



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/65 (32%), Positives = 29/65 (44%)

Query: 1608  TLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIA 1667
             T  V W+ +N PLK  +R    +      L I     ED G Y  +  N+ GEA+ +   
Sbjct: 15679 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV 15738

Query: 1668  IVHSK 1672
             IV  K
Sbjct: 15739 IVLDK 15743



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/172 (19%), Positives = 67/172 (38%), Gaps = 14/172 (8%)

Query: 1246  DTGEYTVRAVNHLGSAHT---SAIVRVIERSDIVTD-TQNEQAIEQIQLLEDAARRTKQ- 1300
             D G   ++ +  + + H+   S   RV     ++T+ TQ E+ + ++  + +  R   + 
Sbjct: 16660 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRS 16719

Query: 1301  -----VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                  V +D+ +   P    A  +     G ++ +E  +   G     + W  +G P+K 
Sbjct: 16720 LAVPIVAKDLVI--EPDVKPAFSSYSVQVGQDLKMEVPIS--GRPKPTITWTKDGLPLKQ 16775

Query: 1356  GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407
               R       D   L +   + +D G Y     N +G+   S  +  + K D
Sbjct: 16776 TTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD 16827



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 2/90 (2%)

Query: 3054  FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGT 3113
             F+D + ++ G+    EA +   G     IEW    K IE S R          +L +   
Sbjct: 17134 FRDTIVVNAGETFRLEADV--HGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDA 17191

Query: 3114  KTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
                D G Y  RA+N  G     V ++ +D+
Sbjct: 17192 IRIDGGQYILRASNVAGSKSFPVNVKVLDR 17221



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 19/70 (27%), Positives = 32/70 (45%)

Query: 3590  RVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             RV WF +G  +     ++  N  G   L +    +   G+YT +A N  G A    K++V
Sbjct: 21492 RVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551

Query: 3650  KGRQGIILEP 3659
             +   G ++ P
Sbjct: 21552 QDTPGKVVGP 21561



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/60 (28%), Positives = 26/60 (43%)

Query: 945   WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
             W   G  +  S R+T   +     LTI+  T+ D G YT    N  G  + +  + I+ K
Sbjct: 23275 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDK 23334



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 2122 KEGDR-AHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            KE D  A FEC     ++P + + W+ +G ++  G +YR   D     L IL     D+ 
Sbjct: 2140 KEKDTMATFECET---SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAE 2196

Query: 2181 TYMC 2184
             Y C
Sbjct: 2197 DYSC 2200



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            F + LQ+I+ + E  +   +C + P     ++ +W+ N+  ++ + + T T   G  ++T
Sbjct: 2223 FVKELQDIE-VPESYSGELECIVSP---ENIEGKWYHNDVELKSNGKYTITSRRGRQNLT 2278

Query: 2438 ISHVRDEDEGVY 2449
            +  V  ED+G Y
Sbjct: 2279 VKDVTKEDQGEY 2290



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 910  EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
            EF+  IKD I + E   A FE     + +  + V+W+KD + ++ + RI          L
Sbjct: 3013 EFRKHIKD-IKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRL 3068

Query: 970  TIKSVTVHDAGHYTCRAYNAIGQA 993
             I S  + DAG YT  A   +  A
Sbjct: 3069 LIPSTRMSDAGKYTVVAGGNVSTA 3092



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 5/93 (5%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
            +    P+  T L +   +EG   H    +    +    V WY  NK + S  +F    + 
Sbjct: 4238 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQ 4293

Query: 1633 GFVALDIMSCLPED-SGTYTCRAINALGEAVTS 1664
                L I     ED  G Y C A+N  G+  TS
Sbjct: 4294 NTYTLVIDKVNTEDHQGEYVCEALNDSGKTATS 4326



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/165 (22%), Positives = 61/165 (36%), Gaps = 11/165 (6%)

Query: 395  VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMIT 453
            VK  +D+ V       F C +  +  P + WF    +I  + N K  +   GNH  L I 
Sbjct: 4812 VKPIRDQHVKPKGTAIFACDIA-KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIK 4870

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            N    D          K     +  +L + E+E     + ++    + + E E    +A 
Sbjct: 4871 NAMPEDIAEYAVEIEGKR----YPAKLTLGEREV----ELLKPIEDVTIYEKESASFDAE 4922

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
                  P   W+  G  + P+P   I  +GG   L + + K   A
Sbjct: 4923 ISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQA 4966



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 4/123 (3%)

Query: 1663 TSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRV 1722
            TS   ++ S+   +     E  L  ++Q++   K    +AQ +V+   P FT+ + D   
Sbjct: 5118 TSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTA 5177

Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782
             E      +  +       + V+W ++G  I  S + +   D     L +K  + +D G 
Sbjct: 5178 VEKDEITLKCEV----SKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGE 5233

Query: 1783 YTC 1785
            Y C
Sbjct: 5234 YVC 5236



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 3/79 (3%)

Query: 635  PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            PP +F  PL+  T  EG     E     V     K++W KNG  I  S ++  +      
Sbjct: 5786 PPVEFTKPLEDQTVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVR 5842

Query: 695  SLDMLSLNIQDSGEYTCRA 713
             L +     +D   YTC A
Sbjct: 5843 KLVIHDCTPEDIKTYTCDA 5861



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/98 (25%), Positives = 39/98 (39%), Gaps = 2/98 (2%)

Query: 766  TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
            T + P+    ++ L  L        E   T    P  ++ W K    +    RIT I N 
Sbjct: 7187 TQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRIT-IENV 7245

Query: 826  GYVS-LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               S + I+  +  D G+Y + AVN  G A +   + V
Sbjct: 7246 PKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 1584  LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSC 1642
             ++ + +K G    F   +  V   T K  W  +   +K+   +T ET+NF  V L I +C
Sbjct: 11020 IEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11076

Query: 1643  LPEDSGTYTCRAINALG 1659
             L  D+G Y     NA G
Sbjct: 11077 LRRDTGEYQITVSNAAG 11093



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/66 (28%), Positives = 28/66 (42%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P   + W K+G+ +    R+  I +   V L I      D G Y + A N  G A  +A 
Sbjct: 11439 PEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAI 11498

Query: 860   IRVAAR 865
             + V  R
Sbjct: 11499 VNVLDR 11504



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/64 (34%), Positives = 27/64 (42%)

Query: 3591  VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             + W   GK L+   RV  I D   V L+I    + D G Y   A N  G A  S  + V 
Sbjct: 11443 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVL 11502

Query: 3651  GRQG 3654
              R G
Sbjct: 11503 DRPG 11506



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 910   EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
             +    +K  +++K G     +A +   G     V W KDG  ++ +  I          L
Sbjct: 12799 DLSVAMKSLLTVKAGTNVCLDATV--FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTL 12856

Query: 970   TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
              + SV   D+G YT  A N+ G  + +  L ++ K
Sbjct: 12857 ELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
             V  G     D  V G+P P V+W  +   ++     K+ + +     L + +V   DSG 
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVNRKDSGD 12868

Query: 463   VTCVARNKSGETAFQCRLNVIEK 485
              T  A N SG  +   +L V++K
Sbjct: 12869 YTITAENSSGSKSATIKLKVLDK 12891



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 6/105 (5%)

Query: 383   IEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
             +EI E+ +AP F    + R    V  G   R    + GRP PEVTW  ++  +++  N  
Sbjct: 14268 VEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRAN-- 14325

Query: 440   ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
              + N      L+I      D+G       N +G+ +    + V++
Sbjct: 14326 -IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLD 14369



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/114 (19%), Positives = 56/114 (49%), Gaps = 5/114 (4%)

Query: 4692  DYKCVAYNSAGRVTVAAKLK--VTQPD--QADNLPALTPLRDIVVYE-GQPAQFKTQITS 4746
             +++ +A N+AG ++  ++    +T  D  +A  +      +D V+ + G+  + +  ++ 
Sbjct: 14931 EFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSG 14990

Query: 4747  KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +  PT++W ++G  +  T   ++     +  L+  ++   D+G +T  AT   G
Sbjct: 14991 RPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15044



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 17/82 (20%), Positives = 35/82 (42%)

Query: 4732  VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             V  G+  +       +  P + W ++   + +T         NN++L I +   ED G +
Sbjct: 15662 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15721

Query: 4792  TCRATTAAGQVETSAKLVVKSK 4813
               + T +AG+   +  ++V  K
Sbjct: 15722 VVKLTNSAGEAIETLNVIVLDK 15743



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/55 (36%), Positives = 24/55 (43%)

Query: 2803  PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSA 2857
             PT  + W  +N PL   TR  +    +   L I     ED G Y  K TNS G A
Sbjct: 15678 PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 2/73 (2%)

Query: 2788  GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
             G ++  E  +     PT  I W  +  PL   TR   T      +L I  T+++D G Y 
Sbjct: 16747 GQDLKMEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYG 16804

Query: 2848  CKATNSKGSATTS 2860
                 N  G  T S
Sbjct: 16805 ITVANVVGQKTAS 16817



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 2/88 (2%)

Query: 1185  NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244
             N   +  G+++ +E  +  +G P   + W  +G  +   +R           L I     
Sbjct: 17822 NTYSIQAGEDLKIE--IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNK 17879

Query: 1245  ADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
              D G+YTV A N  G+A  +  V V+E+
Sbjct: 17880 DDFGKYTVTATNSAGTATENLSVIVLEK 17907



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 2/75 (2%)

Query: 3157  NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             N   ++ G+    E  V+    P+  I W  +G+P++ +TR+         VL I     
Sbjct: 17822 NTYSIQAGEDLKIEIPVIGRPRPN--ISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNK 17879

Query: 3217  HDSGEYVCRAYNKYG 3231
              D G+Y   A N  G
Sbjct: 17880 DDFGKYTVTATNSAG 17894



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 17/65 (26%), Positives = 29/65 (44%)

Query: 1738  GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
             G P+  V W ++G  ++ + R+         +L++K  + ED GTY     N  G     
Sbjct: 18923 GRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 18982

Query: 1798  STLFV 1802
              T+ V
Sbjct: 18983 ITIIV 18987



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 4/86 (4%)

Query: 4627  EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
             E  K  IV  G +   +    G+P+P V W K D  ++   Y  +  T    +L I  A 
Sbjct: 19694 EMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENAN 19751

Query: 4687  PEDEGDYKCVAYN--SAGRVTVAAKL 4710
               D G Y     N  SA  +T+  K+
Sbjct: 19752 RNDSGKYTLTIQNVLSAASLTLVVKV 19777



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 6/70 (8%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ--TGDVSLLIKQIGPGDEGE 143
             G N K +  + G P P V+ +R   PL    K +MR+N +    ++++ +K+    D G 
Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPL----KATMRFNTEITAENLTINLKESVTADAGR 20049

Query: 144   YTCTARNQYG 153
             Y  TA N  G
Sbjct: 20050 YEITAANSSG 20059



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 918   QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
             Q++++ G   H E   +  G     + WLKDG P++ S  +        + L+IK+    
Sbjct: 21075 QVTVRIGHNVHLELPYK--GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKE 21132

Query: 978   DAGHYTCRAYNAIGQATTSANLTIVT 1003
               G YT    NA+     +  +T++T
Sbjct: 21133 HGGKYTVILDNAV--CRIAVPITVIT 21156



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/63 (31%), Positives = 27/63 (42%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P  RV W+KDG  I     +      G  SL +     +  G YTV A N  G A +   
Sbjct: 21489 PVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIK 21548

Query: 860   IRV 862
             ++V
Sbjct: 21549 VKV 21551



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 4521  QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ- 4579
             + V + +G  +RL   V+G  P  + W K G  +       I++   +Y+LLI++   + 
Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL---ASRAIIDTTESYSLLIVDKVNRY 23013

Query: 4580  DSGKYECVAINSAGE 4594
             D+GKY   A N +G+
Sbjct: 23014 DAGKYTIEAENQSGK 23028



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/88 (23%), Positives = 34/88 (38%)

Query: 4726  PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             P + I V  G+P +    I  +  P   W   G+ + E+    +      A L I  T  
Sbjct: 23247 PQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTI 23306

Query: 4786  EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              DTG +T       G    + K+++  K
Sbjct: 23307 RDTGEYTLELKNVTGTTSETIKVIILDK 23334



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            + + P F   +Q V  L EG +A FEA +     P+  V WF +G+ +           F
Sbjct: 2    TTQAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISF 58

Query: 3338 --GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              G   L I    + NSG Y   ATN  G+ ++ A L
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADT 1247
            + EG  +   C++   G P  ++ W+ +G+ +  G R++  +   G  +L I      D 
Sbjct: 1256 ILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDE 1313

Query: 1248 GEYTVRAVNHLGSA 1261
            G YT  A N  G+A
Sbjct: 1314 GIYTAFASNIKGNA 1327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P  I Q   + K+ EG   Q +V++S      V W K+GQ +  S++  I+       L 
Sbjct: 2309 PIAILQGLSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQPSDRVHIVIDKQSHMLL 2367

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            + +  K D+G+Y+     P   + TSG ++V S
Sbjct: 2368 IEDMTKEDAGNYSFTI--PALGLSTSGRVSVYS 2398



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I +  P+   PL +     EG  +HL   +    +    V W+   + V    +FK   D
Sbjct: 4238 IKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQD 4292

Query: 1232 FGFVALDIIHATSAD-TGEYTVRAVNHLGSAHTSAIVRVIERS 1273
                 L I    + D  GEY   A+N  G   TSA + V++R+
Sbjct: 4293 QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 1445 RFVTRPKSI---ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            +FV   K I   E+   G    FEC + P   S     W K+G  +    + R I D   
Sbjct: 4619 KFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKD 4675

Query: 1502 VALDIIDLIAEDSGIYTC 1519
              L IID+   D+G YTC
Sbjct: 4676 RKLHIIDVQLSDAGEYTC 4693



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 7/102 (6%)

Query: 286  QVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            Q ++S    P V WFK+G+ +  S    I T      L ++   KSD G YT       G
Sbjct: 5541 QCEISKADAP-VKWFKDGKEIKPSKNAVIKTDGKKRMLILKKALKSDIGQYTC----DCG 5595

Query: 346  CIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISE 387
               TSG L +E      V+   S  + +T+    E   EISE
Sbjct: 5596 TDKTSGKLDIEDREIKLVRPLHSVEVMETETARFE--TEISE 5635



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            FT PL + + + EG  A  E  ++     N KV+W+ NG  +    ++    D     L 
Sbjct: 5790 FTKPLED-QTVEEGATAVLECEVSRE---NAKVKWFKNGTEILKSKKYEIVADGRVRKLV 5845

Query: 3482 ISPTYPEDSGEYLCRA 3497
            I    PED   Y C A
Sbjct: 5846 IHDCTPEDIKTYTCDA 5861



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 771  QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSL 830
            +F+RPL DL +++E   A FE +L   S    +V+W+KDG  I    +   I       L
Sbjct: 5878 EFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGAVRIL 5933

Query: 831  NIMHLRAEDAGSYT 844
             I     +D   Y+
Sbjct: 5934 VINKCLLDDEAEYS 5947



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 29/56 (51%)

Query: 287  VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            V  +G PRP  TW    + L   ++ ++ T   +  L +  +++SD G YTL  EN
Sbjct: 6919 VPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLEN 6974



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 2/93 (2%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            KP       +  V EG  + +      V  PT  V W+ +G+ V+   R     D     
Sbjct: 7889 KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT--VSWHKDGKEVKASDRLTMKNDHISAH 7946

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L++  +   D G Y     N +G A  + +VKV
Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATASINVKV 7979



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 6/95 (6%)

Query: 69    PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
             PS  +  ++ +      G   +F   +RG P P   WT   + +    K    Y  +T +
Sbjct: 11011 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEI----KTDEHYTVETDN 11066

Query: 129   VS--LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              S  L IK     D GEY  T  N  G    +V++
Sbjct: 11067 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHL 11101



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 2/91 (2%)

Query: 912   KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTI 971
             K  + +QI+IK G     EA +   G      +W K    V  SS +          L I
Sbjct: 12404 KILMPEQITIKAGKKLRIEAHV--YGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12461

Query: 972   KSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             K VT  D+G+Y+  A N+ G  T    + ++
Sbjct: 12462 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVM 12492



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 7/119 (5%)

Query: 4689  DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQ 4743
             +E  ++ +A NSAGR        V   +Q   LP L  LR I     +   G   + +  
Sbjct: 14534 EEYTFQVMAVNSAGRSAPRESRPVIVKEQT-MLPELD-LRGIYQKLVIAKAGDNIKVEIP 14591

Query: 4744  ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
             +  + KPT+ W +   ++ +T          + +L I      D+G +   A    G+V
Sbjct: 14592 VLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEV 14650



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 2651  YDKLV---EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
             Y KLV    G ++ +E  V  R  P   + W K    L    R+          L+IN  
Sbjct: 14574 YQKLVIAKAGDNIKVEIPVLGRPKPT--VTWKKGDQILKQTQRVNFETTATSTILNINEC 14631

Query: 2708  RNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                DSG Y   A N++GE     +I++ D
Sbjct: 14632 VRSDSGPYPLTARNIVGEVGDVITIQVHD 14660



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 5/124 (4%)

Query: 4692  DYKCVAYNSAGRVTVAAKLK--VTQPDQAD--NLPALTPLRD-IVVYEGQPAQFKTQITS 4746
             +++ +A N+AG  +  ++    +T  D+ D   +      +D IVV+ G+  +    I  
Sbjct: 16013 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 16072

Query: 4747  KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
             K  PTIQW++    +  T   ++        L + +    D+G +  +A   AG+   + 
Sbjct: 16073 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 16132

Query: 4807  KLVV 4810
              + V
Sbjct: 16133 NVKV 16136



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/83 (21%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
             V  G+  + D  + G+P P + W   D+++ +    +I   +    +L + +    DSG 
Sbjct: 16058 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT-SLSVKDAVRVDSGN 16116

Query: 463   VTCVARNKSGETAFQCRLNVIEK 485
                 A+N +GE +    + V+++
Sbjct: 16117 YILKAKNVAGERSVTVNVKVLDR 16139



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1974  VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
             +V +P       +  V  G  + +E  ++    PT  + W  +G P++Q  R   T    
Sbjct: 16729 LVIEPDVKPAFSSYSVQVGQDLKMEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLD 16786

Query: 2034  YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L I   + +D G Y     N VG+   T+S+++
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQ--KTASIEI 16820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/105 (21%), Positives = 45/105 (42%), Gaps = 4/105 (3%)

Query: 1301  VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
             + +D+T+  + +     ++I+  E     L+  +  +G     + W  +G+P+K   R  
Sbjct: 17807 IAKDLTIQPSLKLPFNTYSIQAGED----LKIEIPVIGRPRPNISWVKDGEPLKQTTRVN 17862

Query: 1361  PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                      L +     +D G YT  ATN  G A  + ++ V+ K
Sbjct: 17863 VEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 5/94 (5%)

Query: 483   IEKEQVVAPKF---VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539
             I KE+   P F    E   TL V+ G    +     G P P + W K    +       +
Sbjct: 19679 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYV 19736

Query: 540   HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
              T    ++L I  A  +D+  Y  T QNV  + +
Sbjct: 19737 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAAS 19770



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/137 (21%), Positives = 56/137 (40%), Gaps = 3/137 (2%)

Query: 206   KVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSP 265
             K ++TN T+   T        +Y     V  R ++         V   T ID   GPV  
Sbjct: 20319 KASFTNVTETQFTISGLTQNSQYEF--RVFARNAVGSISNPSEVVGPITCIDSYGGPVID 20376

Query: 266   PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
               + +     K + G   + +  +SG P P + W+K+ + L  +    +  T +  ++ +
Sbjct: 20377 LPL-EYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILI 20435

Query: 326   RNTQKSDSGHYTLLAEN 342
             ++  + +SG Y L   N
Sbjct: 20436 KDADRLNSGCYELKLRN 20452



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/70 (25%), Positives = 30/70 (42%)

Query: 4426  EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             E  +  + F G P P + W ++   + +   + I    + S+L I QV   D+  +    
Sbjct: 20790 EDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTI 20849

Query: 4486  ENRGGTAKCS 4495
             EN  G  K S
Sbjct: 20850 ENGVGEPKSS 20859



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 6/109 (5%)

Query: 1701  SAQDEVIT-QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
             + ++ +IT +  +  +P   + V      H E  L   G PK  + WL++G+P++ S  +
Sbjct: 21056 TVKELIITPEVDLSDIPGAQVTVRIGHNVHLE--LPYKGKPKPSISWLKDGLPLKESEFV 21113

Query: 1760  TTMHDFGYVALNMKYVNPEDSGTYTC---RAINELGEAVTSSTLFVQSK 1805
                     + L++K    E  G YT     A+  +   +T  TL   SK
Sbjct: 21114 RFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSK 21162



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 2/61 (3%)

Query: 785   GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
             G N H E  L     P   + W KDG P+  S  +        ++L+I + + E  G YT
Sbjct: 21081 GHNVHLE--LPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21138

Query: 845   V 845
             V
Sbjct: 21139 V 21139



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/79 (21%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 2779  HLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHT 2838
             + + ++ K G+++  +  V+    P  ++ WF +   +      + T+     SL +   
Sbjct: 21467 YFDGLIIKSGESLRIKALVQGR--PVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDA 21524

Query: 2839  YEEDSGIYTCKATNSKGSA 2857
               +  G+YT +A N+ GSA
Sbjct: 21525 TRDHRGVYTVEAKNASGSA 21543



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/68 (29%), Positives = 30/68 (44%)

Query: 2007  PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
             P  RV W+ +G  +++    + T   G  +L +  A  +  G Y  +A NA G A     
Sbjct: 21489 PVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIK 21548

Query: 2067  VKVDAKSG 2074
             VKV    G
Sbjct: 21549 VKVQDTPG 21556



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/75 (26%), Positives = 31/75 (41%)

Query: 499   TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             T++V  G PV L     G P P  +W   G  +  +  + + T    + L I      D 
Sbjct: 23250 TIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 23309

Query: 559   AWYQCTAQNVAGSTA 573
               Y    +NV G+T+
Sbjct: 23310 GEYTLELKNVTGTTS 23324



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)

Query: 403   VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
             V +G + R    + G+P+P   W    +    D + + ++  S  H  L+I      DSG
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQ----DISKRAMIATSETHTELVIKEADRGDSG 23706

Query: 462   VVTCVARNKSGETAFQCRLNVI 483
                 V  NK G+ A   ++ VI
Sbjct: 23707 TYDLVLENKCGKKAVYIKVRVI 23728



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 4429  RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
             R  +   G+P P+ KW +E   I  S    I T  T + L+I++    DS  +  V EN+
Sbjct: 23658 RLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENK 23715

Query: 4489  GG 4490
              G
Sbjct: 23716 CG 23717



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 2403  VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHV-RDEDEGVYMCRASNLLG 2458
             +G P   + WF  +KL+++S  IT  +   Y  + + +V R    G Y  + SN+ G
Sbjct: 24156 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG 24212



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 1444  PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
             PR   R +S   V  GQ+  F   ++  +    +V+W+ NG  +    +    +  G + 
Sbjct: 25877 PRITLRMRS-HRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 25933

Query: 1504  LDIIDLIAEDSGIYTCRAVNLVG 1526
             L+I+D   +DSG Y     N  G
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKG 25956



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/74 (27%), Positives = 30/74 (40%)

Query: 4003  PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAV 4062
             P  +V+W+ NG  L   ++       G + +     + +DSG Y    TN  G     A 
Sbjct: 25904 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYAT 25963

Query: 4063  IKTTGKPGIVYDSQ 4076
             +  TG     Y SQ
Sbjct: 25964 LDVTGGDYTTYASQ 25977



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++  +++G       R+  + +P +K  ++R+   I+ S     + +    S
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPNPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+    ED G Y   A+N +G
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVG 183



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/110 (26%), Positives = 43/110 (39%), Gaps = 5/110 (4%)

Query: 942  RVEWLKDGRPVEASSRITT-FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000
            ++ W KDG+ ++   R    F   G  +L I  V   D G YT  A N  G A  S  L 
Sbjct: 1275 KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLY 1334

Query: 1001 IVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLK 1050
            +     + A +  P  LE +  +      S R+     I   P  + P +
Sbjct: 1335 VEPAAPLGAPTYIP-TLEPVSRIRS---LSPRSVSRSPIRMSPARMSPAR 1380



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 774  RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIM 833
            +PL D   + E + A FE +   V++P  + EW +DG+ +  ++ I S  +     L I 
Sbjct: 2578 KPLTDQ-TVAESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIA 2633

Query: 834  HLRAEDAGSYTVR-AVNKLGEAISTASIRV 862
              + +D G YT + A +K    +   ++++
Sbjct: 2634 ATKLDDIGEYTYKVATSKTSAKLKVEAVKI 2663



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 2245 VTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDI 2304
            +T+      V E KTA FEC+V   + P++ ++   NG  ++ + +F I        L I
Sbjct: 2838 ITKTMKNIEVPETKTASFECEVSHFNVPSMWLK---NGVEIEMSEKFKIVVQGKLHQLII 2894

Query: 2305 QHCVPEDAGEYS 2316
             +   ED+ EY+
Sbjct: 2895 MNTSTEDSAEYT 2906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/64 (29%), Positives = 31/64 (48%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P+++ +WF  G+++    +        I  L+IL     + GEY C A+N+ G  S  A 
Sbjct: 4364 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 4423

Query: 3372 LKCT 3375
            L  T
Sbjct: 4424 LTVT 4427



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 10/100 (10%)

Query: 3691 KPNPPRFTVEIKDNIDVPE---GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            K  P +F  EIKD I       G    F+C V P    T    W  +G       +   +
Sbjct: 4614 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFI 4670

Query: 3748 NDFGFIALDIDYIYARDAGEYTC--RATNKWGSATTTAKI 3785
             D     L I  +   DAGEYTC  R  NK    T+TAK+
Sbjct: 4671 ADGKDRKLHIIDVQLSDAGEYTCVLRLGNK--EKTSTAKL 4708



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 910  EFKTPIKDQISIKE---GGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            +F   IKD I  +    G  A FE  + P   ST    W+KDG  +  S +     +   
Sbjct: 4619 KFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKD 4675

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              L I  V + DAG YTC       + T++A L +
Sbjct: 4676 RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV 4710



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%)

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
            G SA FE  V P + +T    W  +G  I  + + +   D     L I  V+  D+G YT
Sbjct: 4636 GSSAIFECLVSPSTAITT---WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 4692

Query: 1118 VVARNAAGEAQLSASMTVE 1136
             V R    E   +A + VE
Sbjct: 4693 CVLRLGNKEKTSTAKLVVE 4711



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 3/81 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L +   +EG     EC V  SR+   K++WF N   +    +Y+   D     L I
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV--SRE-NAKVKWFKNGTEILKSKKYEIVADGRVRKLVI 5846

Query: 2836 THTYEEDSGIYTCKATNSKGS 2856
                 ED   YTC A + K S
Sbjct: 5847 HDCTPEDIKTYTCDAKDFKTS 5867



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 16/135 (11%)

Query: 1824 LEDSSRYQ-----RREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMR 1877
            LED+  Y       R D +V V++ A  FI++     ++ EG+ A + C I     P   
Sbjct: 6029 LEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQN-LEILEGEKAEFVCSISKESFP--- 6084

Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY-----TCKAINNLGQAVSSI 1932
            V+W  + K L+SG +Y    D     L +     +D G Y       +A  +L   +  +
Sbjct: 6085 VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHL-TVIEKL 6143

Query: 1933 RLNVQSKESIIRDSQ 1947
            R+ V  K++ +++ Q
Sbjct: 6144 RIVVPLKDTRVKEQQ 6158



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 16/180 (8%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            ++I EG+ A +  S+     +S  ++W  + KT+E+  +   +      VL +      D
Sbjct: 6064 LEILEGEKAEFVCSI---SKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQD 6120

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             GTY        G A  +  L  ++K +   P   T +      K+ Q   F C    V+
Sbjct: 6121 MGTYVVMV----GAARAAAHLTVIEKLRIVVPLKDTRV------KEQQEVVFNC---EVN 6167

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
                K +W+ N + +  S++   +       L I      D   Y     N  GE+   A
Sbjct: 6168 TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSA 6227



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 52/267 (19%), Positives = 101/267 (37%), Gaps = 22/267 (8%)

Query: 4371 EVVGDKEITRKITSTETTEIEHKAQTQERV-VEGPVKPSKPPIFTKKMQPCRVFEHEQAR 4429
            +V+   E+  ++ +     + H ++  E + +E P  P  PP+        R  +H    
Sbjct: 7750 DVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR--KHIAIA 7807

Query: 4430 FEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVFVEDSAVFAAV-AEN 4487
            ++        P+I ++ E  P+      ++++   K +   + +  V D      V A N
Sbjct: 7808 WKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVN 7867

Query: 4488 RGGTAK---CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
              G ++    S N+V ++   +       P+  L   ++ V  G+ + +           
Sbjct: 7868 AIGVSEPSEISENVVAKDPDCK-------PTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 7920

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VV 4603
            V W K+GK+V+   R  +  +  +  L + ++   D+G Y     N  G A       V+
Sbjct: 7921 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 7980

Query: 4604 SLPA------TKDKPKPQTKAANAPPE 4624
             LP         D  K   K    PPE
Sbjct: 7981 GLPGPCKDIKASDITKSSCKLTWEPPE 8007



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            ++EG+ L +   V  +  P   + W+ +GK ++   R  + +D     L++      D+G
Sbjct: 7901 VIEGEKLSIP--VPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAG 7958

Query: 2983 IYTCKAYNKRGEAFTSSTV 3001
            IYT    NK G A  S  V
Sbjct: 7959 IYTITLENKLGSATASINV 7977



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/61 (31%), Positives = 28/61 (45%)

Query: 3454 VEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            V W+ +GK +KA  R     D     LE+  +   D+G Y     N  G A  + ++KV 
Sbjct: 7921 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 7980

Query: 3514 G 3514
            G
Sbjct: 7981 G 7981



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/71 (23%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 232  REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
            +E  FR    +   G S+   +T   +++ P+  PK+  +  + +++ G +      +SG
Sbjct: 8151 KEYQFRVR-AENAAGISEPSRATPPTKAVDPIDAPKVILRT-SLEVKRGDEIALDASISG 8208

Query: 292  NPRPRVTWFKN 302
            +P P +TW K+
Sbjct: 8209 SPYPTITWIKD 8219



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/93 (25%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 3423  TVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI 3482
             +V + ++  ++ G N   +A  T    P   V W  +G  LK     +         LE+
Sbjct: 12801 SVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 12858

Query: 3483  SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
                  +DSG+Y   A N+ G    T  +KV  K
Sbjct: 12859 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 12891



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/91 (24%), Positives = 38/91 (41%), Gaps = 2/91 (2%)

Query: 2916  PIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVD 2975
             P  + + +  GQ L +E  +  +  P   I W  +G  L+Q +R  +T      TL + +
Sbjct: 16737 PAFSSYSVQVGQDLKMEVPISGRPKPT--ITWTKDGLPLKQTTRINVTDSLDLTTLSIKE 16794

Query: 2976  VYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
              ++ D G Y     N  G+   S  +    K
Sbjct: 16795 THKDDGGQYGITVANVVGQKTASIEIVTLDK 16825



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 637   PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
             P   +P  + +   G  +  E  I  +G P   I W+K+G+ ++ ++R           L
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIE--IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVL 17872

Query: 697   DMLSLNIQDSGEYTCRAVSATGVA 720
              +   N  D G+YT  A ++ G A
Sbjct: 17873 HIKEGNKDDFGKYTVTATNSAGTA 17896



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/77 (27%), Positives = 32/77 (41%)

Query: 800   PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             P   V W KDG+ +  ++R+    +    SL+I     ED G+Y +   N  G      +
Sbjct: 18925 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPIT 18984

Query: 860   IRVAARSTVTADLGIPE 876
             I V  R      + I E
Sbjct: 18985 IIVLDRPGPPGPIRIDE 19001



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/62 (24%), Positives = 30/62 (48%)

Query: 943   VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             V W KDG+ ++ ++R+    +    +L+IK  +  D G Y     N+ G  T    + ++
Sbjct: 18929 VNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVL 18988

Query: 1003  TK 1004
              +
Sbjct: 18989 DR 18990



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 6/76 (7%)

Query: 86    GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
             G N   E   +G P P +SW +   PL E     +R+++    ++L IK       G+YT
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESE--FVRFSKTENKITLSIKNAKKEHGGKYT 21138

Query: 146   CTARNQYGEAICSVYI 161
                 N    A+C + +
Sbjct: 21139 VILDN----AVCRIAV 21150



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/70 (25%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 2926  GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
             G+ L ++  V+ +  P  ++ W+ +G  +E+    ++T+  G  +L + D      G+YT
Sbjct: 21476 GESLRIKALVQGRPVP--RVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYT 21533

Query: 2986  CKAYNKRGEA 2995
              +A N  G A
Sbjct: 21534 VEAKNASGSA 21543



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/66 (30%), Positives = 29/66 (43%)

Query: 1738  GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
             G P  RV W ++GV IE    +   +  G  +L ++    +  G YT  A N  G A   
Sbjct: 21487 GRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAE 21546

Query: 1798  STLFVQ 1803
               + VQ
Sbjct: 21547 IKVKVQ 21552



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/70 (25%), Positives = 28/70 (40%)

Query: 4431  EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
             +V   G P P + W  E   +K +    I T   ++ L ++     DS  +    EN  G
Sbjct: 22171 DVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 22230

Query: 4491  TAKCSANLVV 4500
                 S  +VV
Sbjct: 22231 VKTFSVTVVV 22240



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%)

Query: 2535  VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             VG P    +WY  G EL    +++ + D    TL + +    D G+Y C A N  G
Sbjct: 24060 VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 24115



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 9/114 (7%)

Query: 3830  PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
             PK +  + +      E V  +     K DP   I W +   L+ +   Y+ +    F SL
Sbjct: 24531 PKTLEGMGAVHALRGEVVSIKIPFSGKPDPV--ITWQKGQDLIDNNGHYQVIVTRSFTSL 24588

Query: 3890  DILY-VYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEA 3942
                  V  +D+G Y+  A N FG D     +    +PD       PRG+K S+A
Sbjct: 24589 VFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPD------PPRGVKVSDA 24636


>AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein
           protein.
          Length = 1045

 Score =  226 bits (553), Expect = 1e-57
 Identities = 124/364 (34%), Positives = 200/364 (54%), Gaps = 9/364 (2%)

Query: 220 DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQE 279
           ++K+ +FE RL+ E+ FR  + +  V ESD +I  + +   G    P   ++ ++ ++ E
Sbjct: 627 EYKISSFEQRLMNEIEFR--LERTPVDESDDEIQHD-EIPTGKCIAPIFDKRLKHFRVTE 683

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT--LRVRNTQKSDSGHYT 337
           G+   F  ++ G P P+V WFK+G+++   N+H  +      T  L + +T   D G+YT
Sbjct: 684 GSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYT 743

Query: 338 LLAENPNGCIVTSGYLAVES-PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
           ++A NP G I  SG+L V+S P  S +      +   ++ +E ++   + E+   P F++
Sbjct: 744 IMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE-PLQERFFRPHFLQ 802

Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              D    EG++ R DC+V+G P PE+TW +N + +  D +HK+LV E+G H+L+I  +T
Sbjct: 803 TPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 862

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
             D+G   C+A NK+G+ +F   L+V+ KE   AP  +E+     V EG PV L  R +G
Sbjct: 863 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIG 922

Query: 517 TPTPRITWQKDGVPI-IPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            P P   W+KD   I      + +H D  G + L I  AK SDA WY  +A+N AG  + 
Sbjct: 923 MPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSC 982

Query: 575 RARL 578
            ARL
Sbjct: 983 TARL 986



 Score =  111 bits (268), Expect = 5e-23
 Identities = 107/418 (25%), Positives = 174/418 (41%), Gaps = 55/418 (13%)

Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI 4382
            +DN+ +T+    + + KK+T     P+  E  +   E  +  + + + E        R  
Sbjct: 598  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLE--------RTP 649

Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
                  EI+H         E P      PIF K+++  RV E     F  +  G P+P +
Sbjct: 650  VDESDDEIQHD--------EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKV 701

Query: 4443 KWYRENFPI-KNSPDFQIHTFSTKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             W+++   I K +   ++      +  L I     +D   +  +A N  G   CS +L+V
Sbjct: 702  YWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761

Query: 4501 EE-----------KRRQGRGGIVP------------PSFTLTAQNVNVTSGQLVRLDTKV 4537
            +            +  +GR  +              P F  T  ++    G+L RLD KV
Sbjct: 762  QSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKV 821

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKIL-EEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            +G  P ++ WL NG+ V PD  +K+L  E G ++LLI     +D+G Y+C+A N  G+  
Sbjct: 822  SGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 881

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               E  V             K     P I+E L++  V EG  +   C+++G P P   W
Sbjct: 882  FSLELSV-----------VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYW 930

Query: 4657 YKGDKLIKPSK-YFQMSRTADEYT-LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             K ++ I  ++    M +    Y  L I  A   D G Y   A N AG V+  A+L +
Sbjct: 931  KKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 988



 Score =  111 bits (266), Expect = 8e-23
 Identities = 83/322 (25%), Positives = 133/322 (41%), Gaps = 22/322 (6%)

Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEE-D 4566
            G  + P F    ++  VT G  V    K+ G     VYW K+GK++     + K+  E D
Sbjct: 665  GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 724

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV-SLPA----------------TK 4609
            GT +L I      D G Y  +A N  G   C    +V SLP                  +
Sbjct: 725  GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 784

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKY 4668
            ++ K   +     P  ++   D +  EG+     CK+ G P P + W   G  ++  + +
Sbjct: 785  ERDKEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 844

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              + R    ++L I      D G YKC+A N  G+ + + +L V   +       L  L+
Sbjct: 845  KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQ 904

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN--AVLLIGNTYEE 4786
            +  V EG P + + ++     P   W ++   IP T +   +H+     A LLI    + 
Sbjct: 905  NCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKS 964

Query: 4787 DTGTFTCRATTAAGQVETSAKL 4808
            D G +T  A   AG V  +A+L
Sbjct: 965  DAGWYTLSAKNEAGIVSCTARL 986



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 67/234 (28%), Positives = 98/234 (41%), Gaps = 13/234 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGY 1767
            AP+F   +K  RV E     F  +++ +  PK  V W ++G  I   N    M     G 
Sbjct: 669  APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPK--VYWFKDGKQISKRNEHCKMRREGDGT 726

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+++    +D G YT  A N  G    S  L VQS   L + S+  SA Q  +     
Sbjct: 727  CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---LPIRSRLTSAGQSHR---GR 780

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-V 1886
            SR Q R+   +          Q  G     EG+    +C++   P P +   W  NG+ V
Sbjct: 781  SRVQERDKEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 838

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            L          + G  +L I  +   D+G Y C A N  GQ   S+ L+V +KE
Sbjct: 839  LPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 892



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 80/310 (25%), Positives = 130/310 (41%), Gaps = 21/310 (6%)

Query: 2941 PDLKIEWYFNGK-VLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P  K+ W+ +GK + ++    K+  +  G  +L +      D G YT  A N +G    S
Sbjct: 697  PVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCS 756

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
              +   S       T   +   G  ++Q  +    KEP Q+        P F     D+V
Sbjct: 757  GHLMVQSLPIRSRLTSAGQSHRGRSRVQERD----KEPLQE----RFFRPHFLQTPGDMV 808

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTT 3116
               EG++   +  +  +G     + W  NG+ +  +ASH++  V   G+  L I      
Sbjct: 809  -AHEGRLCRLDCKV--SGLPPPELTWLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQR 864

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D+GTY C ATNK GQ   S++L  V K   + P     +QN  G+ +G     EC V+ +
Sbjct: 865  DAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNC-GVPEGHPVRLECRVIGM 923

Query: 3177 DDPDMKIEWYHNGQPMRHS-TRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P     W  + + +  +  RI    D  G+  L I   +  D+G Y   A N+ G   
Sbjct: 924  PPP--VFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVS 981

Query: 3235 TRATINCYGK 3244
              A ++ Y +
Sbjct: 982  CTARLDIYAQ 991



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 75/276 (27%), Positives = 124/276 (44%), Gaps = 26/276 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH---RFKTTYDFGY 2034
            P F K +K+  VTEG PV     +  +  P  +V W+ +G+ + + +   + +   D G 
Sbjct: 670  PIFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGD-GT 726

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA---KSGLYLDTLDEQRLKKIQEL 2091
             +L I    ++D G Y   A N  G    +  + V +   +S L       +   ++QE 
Sbjct: 727  CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 786

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
            +K    +P++E     RP FL     +    EG     +C+V  +  P LT  W  NGQ 
Sbjct: 787  DK----EPLQERF--FRPHFLQTPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQP 837

Query: 2152 IR--AGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
            +   A H+     + G  +L I      D+GTY C ATNK G+  N+ +L+++     + 
Sbjct: 838  VLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ--NSFSLELSVVAKEV- 893

Query: 2210 DTQHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRF 2244
              + P  LEK++     +GH  R+E     + PP F
Sbjct: 894  -KKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVF 928



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 76/311 (24%), Positives = 129/311 (41%), Gaps = 22/311 (7%)

Query: 3349 EENSGEYECVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKLQTLEDSMVR 3406
            ++N  E +      LG+  T ++++   +E  I   + +L   +E  LE+    E     
Sbjct: 598  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLERTPVDESDDEI 657

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            + D  +   K  AP+F   L +   + EG    F  ++     P  KV W+ +GK +   
Sbjct: 658  QHD-EIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKR 713

Query: 3467 S---RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            +   + R   D G   L I  T  +D G Y   A N  G    +  + VQ   ++ + S+
Sbjct: 714  NEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQ---SLPIRSR 769

Query: 3524 LPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIP 3583
            L    +    +    E          P  E    P F  TP D++  E      +C++  
Sbjct: 770  LTSAGQSHRGRSRVQERDK------EPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSG 823

Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEAT 3642
            +    +   W  NG+P+L  +  K  + + G   L I  + QRDAG Y C ATN+ G+ +
Sbjct: 824  LPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 881

Query: 3643 VSCKLQVKGRQ 3653
             S +L V  ++
Sbjct: 882  FSLELSVVAKE 892



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--- 4467
            P+FTK +Q     E +   FE    G P P ++WYRE   I++SPDF+I     +S+   
Sbjct: 160  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219

Query: 4468 -----LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
                 L+I +VF EDS  F   A N+ GT    A L V
Sbjct: 220  EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 12/152 (7%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--------MS 4672
            A P   + L++   +EGQ + F C++ G P P V+WY+   LI+ S  F+        M+
Sbjct: 158  AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 217

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN---LPALTPLRD 4729
               +  TL I+E F ED G + C A N  G V+  A+L V   +   N   L +     +
Sbjct: 218  EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 277

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            +   E QP+   ++  S  +P    L EG L+
Sbjct: 278  LAAIEPQPSPPHSEPPSVEQPPKPKL-EGVLV 308



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 72/256 (28%), Positives = 109/256 (42%), Gaps = 28/256 (10%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTLNDFG 3751
            P F   +K +  V EG PV F C++  VG P  ++ WF +G+  +  +   ++    D G
Sbjct: 670  PIFDKRLK-HFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGD-G 725

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
              +L I+   + D G YT  A N  G      +I+CS    +V    +   ++       
Sbjct: 726  TCSLHIESTTSDDDGNYTIMAANPQG------RISCSGHL-MVQSLPIRSRLTSAGQSHR 778

Query: 3812 ERGRISDAPKEEPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
             R R+ +  KE P+      P F+         E    R +C+V     P+L   W  NG
Sbjct: 779  GRSRVQERDKE-PLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNG 835

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS-----CKK 3923
            + +LP       V + G  SL I  +   D+G Y C A N  G++     +S      KK
Sbjct: 836  QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK 895

Query: 3924 LPDII--LQN-QVPRG 3936
             P I+  LQN  VP G
Sbjct: 896  APVILEKLQNCGVPEG 911



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 63/230 (27%), Positives = 95/230 (41%), Gaps = 15/230 (6%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI-KTGHRFRPAYEFDYV 1368
            AP F + L +    EG+ V   C++  VG    +V WF +GK I K     +   E D  
Sbjct: 669  APIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 726

Query: 1369 -ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
             +L + S   +D G YT  A N  G    S  L V   + L + S+  S  +  +     
Sbjct: 727  CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQSHRGRSRV 783

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
                K  + +     +P F+  P  +    EG+    +CK+  +    L   W  NGQPV
Sbjct: 784  QERDKEPLQERF--FRPHFLQTPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 838

Query: 1488 T--IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
                 H+   + + G  +L I  L   D+G Y C A N  G +  S  L+
Sbjct: 839  LPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELS 887



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 61/237 (25%), Positives = 100/237 (42%), Gaps = 13/237 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694
           P F   LK     EG  + F  +I  VG P  K+ W K+G+ I   +    + R G    
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTC 727

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
           SL + S    D G YT  A +  G       L V       R +   ++ +   ++++  
Sbjct: 728 SLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERD 787

Query: 755 KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT 814
           K    E ++E+   RP F++   D+    EGR    + +++ +  P +   W  +G+P+ 
Sbjct: 788 K----EPLQERFF-RPHFLQTPGDM-VAHEGRLCRLDCKVSGLPPPELT--WLLNGQPVL 839

Query: 815 A-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
             +S    +   G  SL I  L   DAG+Y   A NK G+   +  + V A+    A
Sbjct: 840 PDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKA 896



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 7/105 (6%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F K+ Q+   +EG++  F+CRV G P P+V W+     I D  + +IL  +  + A 
Sbjct: 159 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218

Query: 450 ------LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
                 L+I  V   DSG  TC A NK G  +   +L+V   E +
Sbjct: 219 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 62/244 (25%), Positives = 97/244 (39%), Gaps = 13/244 (5%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            LE+    ES +  +  EIP       P+F + L++   + EG    F C++  VG P  K
Sbjct: 645  LERTPVDESDDEIQHDEIPTGKCIA-PIFDKRLKHF-RVTEGSPVTFTCKI--VGIPVPK 700

Query: 2410 VEWFRNEKLIEDSSRITKTH--DFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            V WF++ K I   +   K      G  S+ I     +D+G Y   A+N  G         
Sbjct: 701  VYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 760

Query: 2468 XXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAH 2527
                  + + ++     +  +   +  ER  E     F +P F Q   G     EG+   
Sbjct: 761  VQS---LPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQT-PGDMVAHEGRLCR 816

Query: 2528 YEARVVPVGDPSLRFEWYINGVE-LKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAI 2586
             + +V  +  P L   W +NG   L   S      + G  +L I+ +   DAG Y C A 
Sbjct: 817  LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIAT 874

Query: 2587 NRAG 2590
            N+ G
Sbjct: 875  NKTG 878



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 69/266 (25%), Positives = 118/266 (44%), Gaps = 30/266 (11%)

Query: 1168 QIEEISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            Q +EI   K   P+F + L +   V+EG  +   C++  +G P  +V WF +G+ ++  +
Sbjct: 658  QHDEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRN 714

Query: 1225 ---RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE---RSDIVTD 1278
               + +   D G  +L I   TS D G YT+ A N  G    S  + V     RS + + 
Sbjct: 715  EHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSA 773

Query: 1279 TQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVG 1338
             Q+ +   ++Q  +    + +  R        P F +   ++   EG    L+C++   G
Sbjct: 774  GQSHRGRSRVQERDKEPLQERFFR--------PHFLQTPGDMVAHEGRLCRLDCKVS--G 823

Query: 1339 DQTMRVEWFCNGKPI--KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                 + W  NG+P+     H+     E    +L +  +   D+G Y C ATN+ G+   
Sbjct: 824  LPPPELTWLLNGQPVLPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSF 882

Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQ 1422
            S  L V+AK+      + P  LEK+Q
Sbjct: 883  SLELSVVAKE----VKKAPVILEKLQ 904



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 60/226 (26%), Positives = 102/226 (45%), Gaps = 19/226 (8%)

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS---RVKTINDFGFVILEIGGVYQR 3625
            ++E S   F C+++ +     +V WF +GK +   +   +++   D G   L I      
Sbjct: 681  VTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSD 737

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEI 3685
            D G YT  A N  G  + S  L V   Q + +  +L S  +S      +    + +R++ 
Sbjct: 738  DDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQS-----HRGRSRVQERDKE 789

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP-FATGSRV 3744
             ++ E+   P F ++   ++   EG     DC+V   G P   + W  NG+P     S  
Sbjct: 790  PLQ-ERFFRPHF-LQTPGDMVAHEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHK 845

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              + + G  +L ID +  RDAG Y C ATNK G  + + +++  AK
Sbjct: 846  MLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 891



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 60/242 (24%), Positives = 103/242 (42%), Gaps = 17/242 (7%)

Query: 1571 DEVTTQ---APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            DE+ T    API    LK+  + EG    F  +++ +     KV W+ + K +   +   
Sbjct: 660  DEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIP--VPKVYWFKDGKQISKRNEHC 717

Query: 1628 ETNNFG--FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
            +    G    +L I S   +D G YT  A N  G    SG  +V   +S+ + S+   A 
Sbjct: 718  KMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAG 774

Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
                      +  +   Q+      P F     D+   E +    + ++  +  P+L   
Sbjct: 775  QSHRGRSRVQERDKEPLQERFF--RPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPEL--T 830

Query: 1746 WLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            WL NG P+  +AS+++  + + G  +L +  +   D+GTY C A N+ G+   S  L V 
Sbjct: 831  WLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVV 889

Query: 1804 SK 1805
            +K
Sbjct: 890  AK 891



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 50/172 (29%), Positives = 76/172 (44%), Gaps = 15/172 (8%)

Query: 1789 NELGEAVTSSTLFVQSKASLQ-LESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFI 1847
            NE+    T+S +   +    Q L +Q   A   IQQ +  + Y +  D +  +  AP F 
Sbjct: 107  NEVSSPPTTSAVIPPAVPQAQHLVAQPRVAT--IQQCQSPTNYLQGLDGKPII-AAPVFT 163

Query: 1848 TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT--------SNDF 1899
              L      SEGQ   +ECR++  P P  +VEWY  G +++    +R         +   
Sbjct: 164  KMLQN-LSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPE 220

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
                L I  V+ EDSG +TC A N  G   S  +L+V+  E +  +    SA
Sbjct: 221  EICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 272



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 8/93 (8%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--------L 4778
            L+++   EGQ   F+ ++     P ++W REG LI ++PDF+++ +   ++        L
Sbjct: 166  LQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTL 225

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +I   + ED+G FTC A+   G V + A+L V+
Sbjct: 226  VIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVR 258



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 15/222 (6%)

Query: 3985 LVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY--DFGYVAMNFGWVYPED 4042
            + E     F C++  VG P  KV WF +GK +  +N    +     G  +++      +D
Sbjct: 681  VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDD 738

Query: 4043 SGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             G Y   A N  G       +     P       +   + S  +     +  Q   ++ +
Sbjct: 739  DGNYTIMAANPQGRISCSGHLMVQSLP-------IRSRLTSAGQSHRGRSRVQERDKEPL 791

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY- 4161
            +E   R  P F+  P  +   EG   R  C+V+G P P + WLLNG  ++  + +K+   
Sbjct: 792  QERFFR--PHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 849

Query: 4162 -DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
              G++   I    Q D G  + I             L V+ +
Sbjct: 850  ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 891



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 68/275 (24%), Positives = 113/275 (41%), Gaps = 26/275 (9%)

Query: 751  EDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG 810
            E   + QH E I       P F + L+    + EG    F  ++  +  P  +V W+KDG
Sbjct: 652  ESDDEIQHDE-IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGI--PVPKVYWFKDG 707

Query: 811  RPITASSRITSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
            + I+  +    +   G    SL+I    ++D G+YT+ A N  G    +  + V +    
Sbjct: 708  KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---- 763

Query: 869  TADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
                 +P + R +                    + E   +P F     D ++  EG    
Sbjct: 764  -----LPIRSR-LTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQTPGDMVA-HEGRLCR 816

Query: 929  FEARLEPIGDSTLRVEWLKDGRPV--EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
             + ++  +    L   WL +G+PV  +AS ++      G  +L I  +T  DAG Y C A
Sbjct: 817  LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVR-ETGVHSLLIDPLTQRDAGTYKCIA 873

Query: 987  YNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             N  GQ + S  L++V K+      + P  LEK+Q
Sbjct: 874  TNKTGQNSFSLELSVVAKE----VKKAPVILEKLQ 904



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 59/237 (24%), Positives = 95/237 (40%), Gaps = 19/237 (8%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVS 2832
            +F   L +    EG  + F C +     P  K+ WF + K +     +           S
Sbjct: 671  IFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 728

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE 2892
            L I  T  +D G YT  A N +G  + SG L            Q    ++ L +  Q+  
Sbjct: 729  LHIESTTSDDDGNYTIMAANPQGRISCSGHLM----------VQSLPIRSRLTSAGQSHR 778

Query: 2893 ARLAKGRRPSVPDTE-YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNG 2951
             R     R   P  E + +P + +    +    EG++  L+ +V     P+L   W  NG
Sbjct: 779  GRSRVQERDKEPLQERFFRPHF-LQTPGDMVAHEGRLCRLDCKVSGLPPPEL--TWLLNG 835

Query: 2952 K-VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
            + VL   S   L  + G  +L +  + +RD+G Y C A NK G+   S  +   +K+
Sbjct: 836  QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 892



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 8/103 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
           K  + AP F +    L+  EG+ VV   R  G P+P++ W ++G  I  +P+ RI     
Sbjct: 154 KPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKP 213

Query: 545 AS--------TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            S        TL I    A D+  + CTA N  G+ ++ A+L+
Sbjct: 214 RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLH 256



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 10/110 (9%)

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR------ 1360
            ++ AP F++ L N+   EG  V  ECR++  G  + +VEW+  G  I+    FR      
Sbjct: 156  IIAAPVFTKMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKP 213

Query: 1361 --PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
               A   +   L +  V+ EDSG +TC A+N+ G   +   L V   +DL
Sbjct: 214  RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 37/91 (40%), Positives = 49/91 (53%), Gaps = 11/91 (12%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKTHDFGY 2433
            PVFT+ LQN+ +  EGQ   F+CR+   G P+ KVEW+R   LIEDS   RI +      
Sbjct: 160  PVFTKMLQNL-SASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 2434 V------SMTISHVRDEDEGVYMCRASNLLG 2458
                   ++ I+ V  ED G + C ASN  G
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 23/238 (9%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM---RHSTRIKTVSDFG 3205
            P F   +++   + +G    F C +V +  P  K+ W+ +G+ +       +++   D G
Sbjct: 670  PIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCKMRREGD-G 725

Query: 3206 FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDS-LAKIRELE 3264
               L I  T + D G Y   A N  G       I+C   G + ++SL   S L    +  
Sbjct: 726  TCSLHIESTTSDDDGNYTIMAANPQGR------ISC--SGHLMVQSLPIRSRLTSAGQSH 777

Query: 3265 SLQGAQQQTPSTPSAEP---PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321
              +   Q+    P  E    P F+    D+    EG+    + ++  +  P+L   W  N
Sbjct: 778  RGRSRVQERDKEPLQERFFRPHFLQTPGDMVAH-EGRLCRLDCKVSGLPPPELT--WLLN 834

Query: 3322 GKK-LPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            G+  LP         + G+  L I    + ++G Y+C+ATNK G++S    L   +KE
Sbjct: 835  GQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 892



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 57/214 (26%), Positives = 98/214 (45%), Gaps = 25/214 (11%)

Query: 1077 VEWYFNGKQITSAN---RIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            V W+ +GKQI+  N   +++   D G  +L I S  ++D G YT++A N  G    S  +
Sbjct: 701  VYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 759

Query: 1134 TVET---RSSIDTS-SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPV 1189
             V++   RS + ++   HRG   ++R  E  K  EP+ +       +P F+Q        
Sbjct: 760  MVQSLPIRSRLTSAGQSHRG---RSRVQERDK--EPLQE----RFFRPHFLQ-TPGDMVA 809

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGFVALDIIHATSADTG 1248
             EG+   L+C++   G P   + W  NG+ V   +  K    + G  +L I   T  D G
Sbjct: 810  HEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAG 867

Query: 1249 EYTVRAVNHLG----SAHTSAIVRVIERSDIVTD 1278
             Y   A N  G    S   S + + ++++ ++ +
Sbjct: 868  TYKCIATNKTGQNSFSLELSVVAKEVKKAPVILE 901



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 34/221 (15%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT--THNHTTL 323
           P   Q P +    EG   +   ++SG P P +TW  NGQ ++    H+++   T  H+ L
Sbjct: 798 PHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 857

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
               TQ+ D+G Y         CI T+                     T       E  +
Sbjct: 858 IDPLTQR-DAGTYK--------CIATNK--------------------TGQNSFSLELSV 888

Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
              E   AP  ++  Q+  V EG   R +CRV G P P V ++  D +       +I ++
Sbjct: 889 VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMP-PPVFYWKKDNETIPCTRERISMH 947

Query: 444 E--SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           +  +G   L+I     SD+G  T  A+N++G  +   RL++
Sbjct: 948 QDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 988



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 33/112 (29%), Positives = 49/112 (43%)

Query: 50  TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
           T V+ S D         G+   PIF++  K+ R  +G    F  K+ G P P V W +  
Sbjct: 648 TPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDG 707

Query: 110 APLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             + + N++     E  G  SL I+     D+G YT  A N  G   CS ++
Sbjct: 708 KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 759



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 53/233 (22%), Positives = 93/233 (39%), Gaps = 30/233 (12%)

Query: 524 WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXX 583
           W  +G  +  +P++ I   G   +L I  A   D   Y C A N+ G+ +T A +Y    
Sbjct: 27  WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 584 XXXXXX-----QKRLHLPRPTKVXXXXXXXXXXXXYLRHVER--ARP------------- 623
                      ++   + +P +V             +   +   A+P             
Sbjct: 87  SSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTN 146

Query: 624 YIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS 683
           Y+   +   +   P F   L++++A EG  + FE R++  G P+ K+EW + G  IE S 
Sbjct: 147 YLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSP 204

Query: 684 RFTSIFR--------FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            F  + +            +L +  +  +DSG +TC A +  G   + A LHV
Sbjct: 205 DFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 12/145 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG--- 3751
            P FT ++  N+   EG  V F+CRV+  G P+ +++W+  G           L       
Sbjct: 160  PVFT-KMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 3752 -----FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
                    L I  ++A D+G +TC A+NK+G+ ++ A++      D+     L    S  
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTT 276

Query: 3807 KIKELERGRISDAPKEEPIVSTPPK 3831
             +  +E  + S    E P V  PPK
Sbjct: 277  NLAAIE-PQPSPPHSEPPSVEQPPK 300



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 104/250 (41%), Gaps = 22/250 (8%)

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276
            LE+    E+       E+   K   P F   L+    V EG    F C++  +  P  ++
Sbjct: 645  LERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KV 701

Query: 2277 EFYHNGKALQSAARFHITF---DFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAIS 2331
             ++ +GK + S    H        G  SL I+    +D G Y++ A N  G   C+  + 
Sbjct: 702  YWFKDGKQI-SKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 760

Query: 2332 M-TVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390
            + ++  +  + S  Q   G  +++E +  EP +           RP F Q   ++    E
Sbjct: 761  VQSLPIRSRLTSAGQSHRGRSRVQERDK-EPLQERFF-------RPHFLQTPGDMV-AHE 811

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            G+    DC++   G P  ++ W  N + ++ D+S      + G  S+ I  +   D G Y
Sbjct: 812  GRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 869

Query: 2450 MCRASNLLGE 2459
             C A+N  G+
Sbjct: 870  KCIATNKTGQ 879



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 57/231 (24%), Positives = 89/231 (38%), Gaps = 13/231 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG---AR 2690
            + TG   APIF   LK + ++ EG  V    ++     P  K+ WFK+G  ++      +
Sbjct: 662  IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCK 718

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            ++   D G  +L I S  +DD G YT  A N  G    +  + ++     +   L     
Sbjct: 719  MRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSAGQ 775

Query: 2751 DRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWF 2810
               G                     F+    ++V  EG     +C V  S  P  ++ W 
Sbjct: 776  SHRGR-SRVQERDKEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKV--SGLPPPELTWL 832

Query: 2811 FNNKP-LPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
             N +P LP  +      +    SL I    + D+G Y C ATN  G  + S
Sbjct: 833  LNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFS 883



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 14/151 (9%)

Query: 1678 ESQHEGALPR---LNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARL 1734
            ++QH  A PR   + Q +  + Y +     + I  APVFT  ++++  +E Q   FE R+
Sbjct: 125  QAQHLVAQPRVATIQQCQSPTNYLQ-GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRV 183

Query: 1735 IPVGDPKLRVEWLRNGVPIEAS-------NRLTTMHDFGYV-ALNMKYVNPEDSGTYTCR 1786
               G P  +VEW R G  IE S        +  +M +   +  L +  V  EDSG +TC 
Sbjct: 184  --KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCT 241

Query: 1787 AINELGEAVTSSTLFVQSKASLQLESQHESA 1817
            A N+ G   + + L V+    L       SA
Sbjct: 242  ASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 272



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIR----- 4559
            G+  I  P FT   QN++ + GQLV  + +V G     V W + G  ++  PD R     
Sbjct: 153  GKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKK 212

Query: 4560 -NKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
               + E +   TL+I E + +DSG + C A N  G
Sbjct: 213  PRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 43/149 (28%), Positives = 62/149 (41%), Gaps = 13/149 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APVFT  L N+ +  EG+   FE R+     P  KVEWY  G  ++    FR        
Sbjct: 159  APVFTKMLQNL-SASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRS 215

Query: 3479 ILE--------ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530
            + E        I+  + EDSG + C A N YG   + A + V+G  ++     L      
Sbjct: 216  MAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANST 275

Query: 3531 TIDKIAALEGYSGTVDTLTPEAESGNPPE 3559
            T   +AA+E       +  P  E    P+
Sbjct: 276  T--NLAAIEPQPSPPHSEPPSVEQPPKPK 302



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 62/260 (23%), Positives = 97/260 (37%), Gaps = 43/260 (16%)

Query: 3456 WYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            WY  GK L+               L I+  + ED+G Y C A N YG   T+A + ++G 
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 3516 RNIILESQLPKGMEGTIDK---IAALEGYSGTVDTLTPEAE------------------- 3553
             +   E    K     I K   +++    S  +    P+A+                   
Sbjct: 87   SSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTN 146

Query: 3554 -----SGNP----PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG-----KP 3599
                  G P    P FT    +L  SE     FECR+      S +VEW+  G      P
Sbjct: 147  YLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSP 204

Query: 3600 ---LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGII 3656
               +L               L I  V+  D+G +TC A+N++G  +   +L V+G + + 
Sbjct: 205  DFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS 264

Query: 3657 LEPQLPSHFKSGTESIQKLE 3676
                L  H  + T ++  +E
Sbjct: 265  NNGSL--HSANSTTNLAAIE 282



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 11/97 (11%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            +PI++ P  F   +++ +  E + V FECRV+    PK  +EWYR G L+     +R + 
Sbjct: 154  KPIIAAPV-FTKMLQNLSASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQ 210

Query: 3883 DMG--------FVSLDILYVYAEDSGEYICRAVNDFG 3911
                         +L I  V+AEDSG + C A N +G
Sbjct: 211  KKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 18/143 (12%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG--- 3205
            P FT  +QN+    +GQ   FEC V     P  K+EWY  G  +  S   + +       
Sbjct: 160  PVFTKMLQNLSA-SEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 3206 -----FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD-SLAK 3259
                    L IA     DSG + C A NKYG   + A ++  G      E L  + SL  
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGN-----EDLSNNGSLHS 271

Query: 3260 IRELESLQGAQQQTPSTPSAEPP 3282
                 +L   + Q PS P +EPP
Sbjct: 272  ANSTTNLAAIEPQ-PSPPHSEPP 293



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 21/142 (14%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-------- 2160
            PVF   L +L +  EG    FECRV+    P   ++W+  G  I     +R         
Sbjct: 160  PVFTKMLQNL-SASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKI 2220
                    L I   +AEDSG + C A+NK G   +   L V G+ ++       NG    
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL-----SNNG---- 267

Query: 2221 RQLEAQGHSTRIEVEEPKISPP 2242
              L +   +T +   EP+ SPP
Sbjct: 268  -SLHSANSTTNLAAIEPQPSPP 288



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 20/58 (34%), Positives = 32/58 (55%)

Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            W  EG  +  +PD  ++  GN   L I   +EEDTG ++C A+   G   TSA++ ++
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 84



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 10/99 (10%)

Query: 64  GRPGEP--SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE------- 114
           G  G+P  + P+F ++ +N   ++G    FE +++G P+P V W R +  L+E       
Sbjct: 150 GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYR-EGTLIEDSPDFRI 208

Query: 115 CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
             K      E     +L+I ++   D G +TCTA N+YG
Sbjct: 209 LQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 10/105 (9%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--------STH 2826
            VF   L N+   EG  + FEC V+ +  P  K+EW+     +     ++           
Sbjct: 161  VFTKMLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAE 218

Query: 2827 DFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
                 +L I   + EDSG +TC A+N  G+ ++   L   G++++
Sbjct: 219  PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 58/224 (25%), Positives = 89/224 (39%), Gaps = 43/224 (19%)

Query: 2947 WYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY---C 3003
            WY  GK LE      +       +L + + +E D+G Y+C A N  G   TS+ +Y    
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 3004 TSKDN-------LIERTQHPKGTE-----------GLEKIQNLEDSLRKEPGQQPDDDT- 3044
            +S D+        + R Q P                + + Q+L    R    QQ    T 
Sbjct: 87   SSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTN 146

Query: 3045 ------GRP----PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS 3094
                  G+P    P FT + +++   SEGQ+  +E  +   G  S  +EW+  G  IE S
Sbjct: 147  YLQGLDGKPIIAAPVFTKMLQNL-SASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDS 203

Query: 3095 HRIRTVY--------AFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
               R +            +  L I      DSG ++C A+NK+G
Sbjct: 204  PDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+V +EG+  +   +++    P + WL  G  ++P+     ++ E     LLI    + D
Sbjct: 806  DMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRD 865

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             GT+ C AT   GQ   S +L V +K
Sbjct: 866  AGTYKCIATNKTGQNSFSLELSVVAK 891



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 63/232 (27%), Positives = 90/232 (38%), Gaps = 17/232 (7%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH-- 1491
            D I     I P F  R K    V EG  V F CK+  +     KV WFK+G+ ++  +  
Sbjct: 660  DEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEH 716

Query: 1492 -RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             + R   D G  +L I    ++D G YT  A N  G    S  L  +S    +RS    A
Sbjct: 717  CKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSA 773

Query: 1551 GLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL 1609
            G    Q    RS+    D    +     P    +  ++   EG+    + ++  +    L
Sbjct: 774  G----QSHRGRSRVQERDKEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPEL 829

Query: 1610 KVEWYHNNKP-LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
               W  N +P L   S        G  +L I      D+GTY C A N  G+
Sbjct: 830  --TWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ 879



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL--------TSDFGFVTLDLVDV 2976
            EGQ++  E +V  K  P  K+EWY  G ++E    F++               TL + +V
Sbjct: 173  EGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 230

Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL 3009
            +  DSG +TC A NK G   + + ++    ++L
Sbjct: 231  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGD 128
           +P I E++ +N    +G   + E ++ G P PV  W +K    + C +  +  + + TG 
Sbjct: 896 APVILEKL-QNCGVPEGHPVRLECRVIGMPPPVFYW-KKDNETIPCTRERISMHQDTTGY 953

Query: 129 VSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
             LLI+     D G YT +A+N+ G   C+
Sbjct: 954 ACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 983



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 11/132 (8%)

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
            +A I++ +S     Q     P    P F   +Q+++   EGQ   FE R+     P  KV
Sbjct: 135  VATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSAS-EGQLVVFECRVKGAPSP--KV 191

Query: 3317 EWFYNGKKLPHGHRYRTFHDFG--------IVILDILYCYEENSGEYECVATNKLGRDST 3368
            EW+  G  +     +R              I  L I   + E+SG + C A+NK G  S+
Sbjct: 192  EWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSS 251

Query: 3369 KANLKCTSKENL 3380
             A L     E+L
Sbjct: 252  IAQLHVRGNEDL 263



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 10/93 (10%)

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG--------YVALDIIDL 1509
            EGQ V FEC+++       KVEW++ G  +     FR +               L I ++
Sbjct: 173  EGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 230

Query: 1510 IAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
             AEDSG +TC A N  GT     +L  R   D+
Sbjct: 231  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF-ATGS 3742
            E+++  ++       +E   N  VPEG PV  +CRV  +G P     W  +      T  
Sbjct: 885  ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV--IGMPPPVFYWKKDNETIPCTRE 942

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            R+    D  G+  L I      DAG YT  A N+ G  + TA++   A+
Sbjct: 943  RISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 991



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/106 (30%), Positives = 43/106 (40%), Gaps = 6/106 (5%)

Query: 3185 WYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244
            WY  G+ + +S  I  V       L IA     D+G Y C A N YG D T A I   G 
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG- 85

Query: 3245 GGVYLESLQPDSLAKIRELESLQGAQQ-QTPSTPSAEPPKFITQIQ 3289
                + S   +      E+  +Q   +  +P T SA  P  + Q Q
Sbjct: 86   ----VSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQ 127



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 1/86 (1%)

Query: 2013 WYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            WYC G+ ++              +L I  A+ EDTG Y C A+N  G   T++ + ++  
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 2073 SGLYLD-TLDEQRLKKIQELEKYERP 2097
            S    +   +++ + +IQ+  +   P
Sbjct: 87   SSSDSEGDPNKEEMNRIQKPNEVSSP 112



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 11/129 (8%)

Query: 1955 IQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWY 2014
            IQ  +  + Y + + D   ++  P F K ++N   +EG  V  E  +     P+ +VEWY
Sbjct: 138  IQQCQSPTNYLQGL-DGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGA--PSPKVEWY 194

Query: 2015 CNGRPVQQGHRFKTTYDFG--------YVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
              G  ++    F+                 L I   +AED+G + C A+N  G   + + 
Sbjct: 195  REGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQ 254

Query: 2067 VKVDAKSGL 2075
            + V     L
Sbjct: 255  LHVRGNEDL 263



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 8/88 (9%)

Query: 4547 WLKNGKKVQ--PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC--- 4601
            W   GK+++  PDI   I++    ++L I EA+ +D+G+Y C A N  G     AE    
Sbjct: 27   WYCEGKELENSPDIH--IVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 84

Query: 4602 -VVSLPATKDKPKPQTKAANAPPEIIEP 4628
             V S  +  D  K +      P E+  P
Sbjct: 85   GVSSSDSEGDPNKEEMNRIQKPNEVSSP 112



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/58 (34%), Positives = 28/58 (48%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            WY E   ++NSPD  I        L I + F ED+  ++  A N  GT   SA + +E
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 84



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           + ++  + P  +  LQ+ G + EG     E ++  +  P     W KD   I  +    S
Sbjct: 889 VAKEVKKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERIS 945

Query: 822 IFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           +     GY  L I   +  DAG YT+ A N+ G    TA + + A+
Sbjct: 946 MHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 991



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 11/91 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-------- 2559
            P+FT++L   S   EGQ   +E RV   G PS + EWY  G  ++    FR         
Sbjct: 160  PVFTKMLQNLSAS-EGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 2560 THDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   TL I  V A D+G + C A N+ G
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           +G   + + K+ G P P ++W     P++    + M   E TG  SLLI  +   D G Y
Sbjct: 811 EGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRE-TGVHSLLIDPLTQRDAGTY 869

Query: 145 TCTARNQYGE 154
            C A N+ G+
Sbjct: 870 KCIATNKTGQ 879



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 9/121 (7%)

Query: 2278 FYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
            +Y  GK L+++   HI       SL I     ED G YS  A N  G  T + S  +  +
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYG--TDSTSAEIYIE 84

Query: 2338 GSIISESQRPEGLEKIRELE-----SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQ 2392
            G   S+S+     E++  ++     S+ P     IP  V + + +  QP   +  IQ+ Q
Sbjct: 85   GVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQP--RVATIQQCQ 142

Query: 2393 T 2393
            +
Sbjct: 143  S 143



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 19/65 (29%), Positives = 34/65 (52%)

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            WY   K ++ S    + +  + ++L I+EAF ED G Y C A N  G  + +A++ +   
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 4716 DQADN 4720
              +D+
Sbjct: 87   SSSDS 91



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3318 WFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            W+  GK+L +           +  L I   +EE++G Y C A+N  G DST A +
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 81



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--------TE 1628
            AP+ T  L+N+   EGQ   FE R+      + KVEWY     ++    F        + 
Sbjct: 159  APVFTKMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
                    L I     EDSG +TC A N  G    S IA +H
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG--TVSSIAQLH 256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 4/117 (3%)

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
            W+  GK L +      +      ++     + ED+G Y C A+N+YG D T A I   G 
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 4069 PGIVYDSQLPKHMKSIEKIRE-MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEE 4124
                 DS+   + + + +I++  E S   T   V+  +  +   + V+ P   T+++
Sbjct: 87   SS--SDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHL-VAQPRVATIQQ 140



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            PVF  +   ++  EG+   F CRV G P P+V W   G  I +   +++
Sbjct: 160  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRI 208



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 21/55 (38%), Positives = 25/55 (45%)

Query: 3865 WYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            WY  GK L +      V      SL I   + ED+G Y C A N +G D T A I
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 81



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 4/88 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-- 1764
            + +APV    +++  V E      E R+I  G P     W ++   I  +    +MH   
Sbjct: 893  VKKAPVILEKLQNCGVPEGHPVRLECRVI--GMPPPVFYWKKDNETIPCTRERISMHQDT 950

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELG 1792
             GY  L ++     D+G YT  A NE G
Sbjct: 951  TGYACLLIQPAKKSDAGWYTLSAKNEAG 978



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/127 (22%), Positives = 53/127 (41%), Gaps = 5/127 (3%)

Query: 2809 WFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGD 2868
            W+   K L +          +  SL I   +EED+G Y+C A+N  G+ +TS  +   G 
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 2869 KNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWII--PIAAEHQLVEG 2926
             +   D++    K  +  +++  E          +P    P+ + ++  P  A  Q  + 
Sbjct: 87   SS--SDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPA-VPQAQHLVAQPRVATIQQCQS 143

Query: 2927 QVLHLEG 2933
               +L+G
Sbjct: 144  PTNYLQG 150



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/101 (22%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ--------RLINSNKHEI 314
           ++ P   +  +N    EG    F+ ++ G P P+V W++ G         R++      +
Sbjct: 157 IAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
                  TL +      DSG +T  A N  G + +   L V
Sbjct: 217 AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/65 (32%), Positives = 31/65 (47%)

Query: 1079 WYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            WY  GK++ ++  I         +L IA    ED+G Y+  A N  G    SA + +E  
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 1139 SSIDT 1143
            SS D+
Sbjct: 87   SSSDS 91



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT-VGSRFKTYYDF 1232
            K  PV ++ L N   V EG  + LECR+  M  P     W  +  ++     R   + D 
Sbjct: 894  KKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERISMHQDT 950

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             G+  L I  A  +D G YT+ A N  G    +A
Sbjct: 951  TGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTA 984



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 15/55 (27%), Positives = 28/55 (50%)

Query: 3731 WFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            W+  G+       +H +      +L I   +  D G Y+C A+N +G+ +T+A+I
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 81



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 37/164 (22%), Positives = 59/164 (35%), Gaps = 11/164 (6%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY---KLTYDGMYHF 4167
            P+F        V EG    F C++ G P P+V W  +G  I   + +   +   DG    
Sbjct: 670  PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRT 4227
             I  T   D G   ++             L V  +    R  L +A +     +   +R 
Sbjct: 730  HIESTTSDDDGNYTIMAANPQGRISCSGHLMV--QSLPIRSRLTSAGQSHRGRSRVQERD 787

Query: 4228 ETELEKTFEERQVLQRQG-VIDH-----RPELKPKVIKEPETEW 4265
            +  L++ F     LQ  G ++ H     R + K   +  PE  W
Sbjct: 788  KEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTW 831



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/101 (23%), Positives = 42/101 (41%)

Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           W+  G+ L NS    I+   N  +L +    + D+G Y+  A N  G   TS  + +E  
Sbjct: 27  WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ 399
           + S  +   ++   +  Q+  E     +  A+ P  V   Q
Sbjct: 87  SSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQ 127



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/55 (34%), Positives = 27/55 (49%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            W+  GK +E S  I  V A  +  L I      D+G YSC A+N +G    S ++
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 81



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG-----KP---LLHKNRFTP 4024
            P F   +Q+  S  E +   FEC++   G P+ KVEW+  G      P   +L K   + 
Sbjct: 160  PVFTKMLQN-LSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQL 4077
                    +    V+ EDSG + C A+N YG   + A +   G   +  +  L
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSL 269



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/57 (26%), Positives = 27/57 (47%)

Query: 1346 WFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            W+C GK ++           +  +L +   + ED+G Y+C A+N  G   TS  + +
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 83



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY------ 1230
            PVF + L N    SEG+ +  ECR++  G P+ +VEW+  G  +     F+         
Sbjct: 160  PVFTKMLQNLS-ASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 1231 --DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
                    L I    + D+G +T  A N  G+  + A + V    D+
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263


>AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein
            myopalladin, 145 kDa (MYOP) protein.
          Length = 1320

 Score =  226 bits (553), Expect = 1e-57
 Identities = 124/364 (34%), Positives = 200/364 (54%), Gaps = 9/364 (2%)

Query: 220  DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQE 279
            ++K+ +FE RL+ E+ FR  + +  V ESD +I  + +   G    P   ++ ++ ++ E
Sbjct: 902  EYKISSFEQRLMNEIEFR--LERTPVDESDDEIQHD-EIPTGKCIAPIFDKRLKHFRVTE 958

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT--LRVRNTQKSDSGHYT 337
            G+   F  ++ G P P+V WFK+G+++   N+H  +      T  L + +T   D G+YT
Sbjct: 959  GSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYT 1018

Query: 338  LLAENPNGCIVTSGYLAVES-PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            ++A NP G I  SG+L V+S P  S +      +   ++ +E ++   + E+   P F++
Sbjct: 1019 IMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE-PLQERFFRPHFLQ 1077

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
               D    EG++ R DC+V+G P PE+TW +N + +  D +HK+LV E+G H+L+I  +T
Sbjct: 1078 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 1137

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
              D+G   C+A NK+G+ +F   L+V+ KE   AP  +E+     V EG PV L  R +G
Sbjct: 1138 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIG 1197

Query: 517  TPTPRITWQKDGVPI-IPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
             P P   W+KD   I      + +H D  G + L I  AK SDA WY  +A+N AG  + 
Sbjct: 1198 MPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSC 1257

Query: 575  RARL 578
             ARL
Sbjct: 1258 TARL 1261



 Score =  111 bits (266), Expect = 8e-23
 Identities = 83/322 (25%), Positives = 133/322 (41%), Gaps = 22/322 (6%)

Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEE-D 4566
            G  + P F    ++  VT G  V    K+ G     VYW K+GK++     + K+  E D
Sbjct: 940  GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 999

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV-SLPA----------------TK 4609
            GT +L I      D G Y  +A N  G   C    +V SLP                  +
Sbjct: 1000 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1059

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKY 4668
            ++ K   +     P  ++   D +  EG+     CK+ G P P + W   G  ++  + +
Sbjct: 1060 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 1119

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              + R    ++L I      D G YKC+A N  G+ + + +L V   +       L  L+
Sbjct: 1120 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQ 1179

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN--AVLLIGNTYEE 4786
            +  V EG P + + ++     P   W ++   IP T +   +H+     A LLI    + 
Sbjct: 1180 NCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKS 1239

Query: 4787 DTGTFTCRATTAAGQVETSAKL 4808
            D G +T  A   AG V  +A+L
Sbjct: 1240 DAGWYTLSAKNEAGIVSCTARL 1261



 Score =  109 bits (263), Expect = 2e-22
 Identities = 106/418 (25%), Positives = 173/418 (41%), Gaps = 55/418 (13%)

Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI 4382
            +DN+ +T+    + + KK+T     P+  E  +   E  +  + + + E        R  
Sbjct: 873  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLE--------RTP 924

Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
                  EI+H         E P      PIF K+++  RV E     F  +  G P+P +
Sbjct: 925  VDESDDEIQHD--------EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKV 976

Query: 4443 KWYRENFPI-KNSPDFQIHTFSTKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             W+++   I K +   ++      +  L I     +D   +  +A N  G   CS +L+V
Sbjct: 977  YWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036

Query: 4501 EE-----------KRRQGRGGIVP------------PSFTLTAQNVNVTSGQLVRLDTKV 4537
            +            +  +GR  +              P F     ++    G+L RLD KV
Sbjct: 1037 QSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV 1096

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKIL-EEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            +G  P ++ WL NG+ V PD  +K+L  E G ++LLI     +D+G Y+C+A N  G+  
Sbjct: 1097 SGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 1156

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               E  V             K     P I+E L++  V EG  +   C+++G P P   W
Sbjct: 1157 FSLELSV-----------VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYW 1205

Query: 4657 YKGDKLIKPSK-YFQMSRTADEYT-LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             K ++ I  ++    M +    Y  L I  A   D G Y   A N AG V+  A+L +
Sbjct: 1206 KKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 67/234 (28%), Positives = 98/234 (41%), Gaps = 13/234 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGY 1767
            AP+F   +K  RV E     F  +++ +  PK  V W ++G  I   N    M     G 
Sbjct: 944  APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPK--VYWFKDGKQISKRNEHCKMRREGDGT 1001

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+++    +D G YT  A N  G    S  L VQS   L + S+  SA Q  +     
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---LPIRSRLTSAGQSHR---GR 1055

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-V 1886
            SR Q R+   +          Q  G     EG+    +C++   P P +   W  NG+ V
Sbjct: 1056 SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 1113

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            L          + G  +L I  +   D+G Y C A N  GQ   S+ L+V +KE
Sbjct: 1114 LPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 64/266 (24%), Positives = 111/266 (41%), Gaps = 30/266 (11%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P+F ++  +  V EG  V L+   VG P P++ W  +G  +  +P++ I   G   +L I
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328

Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXX-----XQKRLHLPRPTKVXXXX 605
             A   D   Y C A N+ G+ +T A +Y               ++   + +P +V    
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 388

Query: 606 XXXXXXXXYLRHVER--ARP-------------YIPPGEEDRVYPPPQFIVPLKSVTAME 650
                    +   +   A+P             Y+   +   +   P F   L++++A E
Sbjct: 389 TTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASE 448

Query: 651 GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--------FGYISLDMLSLN 702
           G  + FE R++  G P+ K+EW + G  IE S  F  + +            +L +  + 
Sbjct: 449 GQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVF 506

Query: 703 IQDSGEYTCRAVSATGVAETKAVLHV 728
            +DSG +TC A +  G   + A LHV
Sbjct: 507 AEDSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 80/310 (25%), Positives = 130/310 (41%), Gaps = 21/310 (6%)

Query: 2941 PDLKIEWYFNGK-VLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P  K+ W+ +GK + ++    K+  +  G  +L +      D G YT  A N +G    S
Sbjct: 972  PVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCS 1031

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
              +   S       T   +   G  ++Q  +    KEP Q+        P F     D+V
Sbjct: 1032 GHLMVQSLPIRSRLTSAGQSHRGRSRVQERD----KEPLQE----RFFRPHFLQAPGDMV 1083

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTT 3116
               EG++   +  +  +G     + W  NG+ +  +ASH++  V   G+  L I      
Sbjct: 1084 -AHEGRLCRLDCKV--SGLPPPELTWLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQR 1139

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D+GTY C ATNK GQ   S++L  V K   + P     +QN  G+ +G     EC V+ +
Sbjct: 1140 DAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNC-GVPEGHPVRLECRVIGM 1198

Query: 3177 DDPDMKIEWYHNGQPMRHS-TRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P     W  + + +  +  RI    D  G+  L I   +  D+G Y   A N+ G   
Sbjct: 1199 PPP--VFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVS 1256

Query: 3235 TRATINCYGK 3244
              A ++ Y +
Sbjct: 1257 CTARLDIYAQ 1266



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 76/276 (27%), Positives = 125/276 (45%), Gaps = 26/276 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH---RFKTTYDFGY 2034
            P F K +K+  VTEG PV     +  +  P  +V W+ +G+ + + +   + +   D G 
Sbjct: 945  PIFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGD-GT 1001

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA---KSGLYLDTLDEQRLKKIQEL 2091
             +L I    ++D G Y   A N  G    +  + V +   +S L       +   ++QE 
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 1061

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
            +K    +P++E     RP FL A   +    EG     +C+V  +  P LT  W  NGQ 
Sbjct: 1062 DK----EPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQP 1112

Query: 2152 IR--AGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
            +   A H+     + G  +L I      D+GTY C ATNK G+  N+ +L+++     + 
Sbjct: 1113 VLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ--NSFSLELSVVAKEV- 1168

Query: 2210 DTQHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRF 2244
              + P  LEK++     +GH  R+E     + PP F
Sbjct: 1169 -KKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVF 1203



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 75/311 (24%), Positives = 128/311 (41%), Gaps = 22/311 (7%)

Query: 3349 EENSGEYECVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKLQTLEDSMVR 3406
            ++N  E +      LG+  T ++++   +E  I   + +L   +E  LE+    E     
Sbjct: 873  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLERTPVDESDDEI 932

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            + D  +   K  AP+F   L +   + EG    F  ++     P  KV W+ +GK +   
Sbjct: 933  QHD-EIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKR 988

Query: 3467 S---RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            +   + R   D G   L I  T  +D G Y   A N  G    +  + VQ   ++ + S+
Sbjct: 989  NEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQ---SLPIRSR 1044

Query: 3524 LPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIP 3583
            L    +    +    E          P  E    P F   P D++  E      +C++  
Sbjct: 1045 LTSAGQSHRGRSRVQERDK------EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSG 1098

Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEAT 3642
            +    +   W  NG+P+L  +  K  + + G   L I  + QRDAG Y C ATN+ G+ +
Sbjct: 1099 LPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 1156

Query: 3643 VSCKLQVKGRQ 3653
             S +L V  ++
Sbjct: 1157 FSLELSVVAKE 1167



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 46/290 (15%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            +E + Q P FT  ++   V E      +   I VG P  +V W   G  +E S  +  + 
Sbjct: 262  EEPLGQPPRFTQKLRSREVPEGTRVQLDC--IVVGIPPPQVRWYCEGKELENSPDIHIVQ 319

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ-HESALQKIQ 1822
                 +L +     ED+G Y+C A N  G   TS+ ++++  +S   E   ++  + +IQ
Sbjct: 320  AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQ 379

Query: 1823 Q-LEDSSRYQRREDVEVAVNQA------PRFIT--QLNGPTKLSEG-------------- 1859
            +  E SS       +  AV QA      PR  T  Q   PT   +G              
Sbjct: 380  KPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTK 439

Query: 1860 ----------QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR--------TSNDFGF 1901
                      Q   +ECR++  P P  +VEWY  G +++    +R         +     
Sbjct: 440  MLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPEEI 497

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
              L I  V+ EDSG +TC A N  G   S  +L+V+  E +  +    SA
Sbjct: 498  CTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 547



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 31/99 (31%), Positives = 53/99 (53%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP   + L+ + V EG  ++  C +VG P P V+WY   K ++ S    + +  + ++L 
Sbjct: 268  PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            I+EAF ED G Y C A N  G  + +A++ +     +D+
Sbjct: 328  IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDS 366



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--- 4467
            P+FTK +Q     E +   FE    G P P ++WYRE   I++SPDF+I     +S+   
Sbjct: 435  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494

Query: 4468 -----LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
                 L+I +VF EDS  F   A N+ GT    A L V
Sbjct: 495  EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 12/152 (7%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--------MS 4672
            A P   + L++   +EGQ + F C++ G P P V+WY+   LI+ S  F+        M+
Sbjct: 433  AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 492

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN---LPALTPLRD 4729
               +  TL I+E F ED G + C A N  G V+  A+L V   +   N   L +     +
Sbjct: 493  EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 552

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            +   E QP+   ++  S  +P    L EG L+
Sbjct: 553  LAAIEPQPSPPHSEPPSVEQPPKPKL-EGVLV 583



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 72/256 (28%), Positives = 109/256 (42%), Gaps = 28/256 (10%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTLNDFG 3751
            P F   +K +  V EG PV F C++  VG P  ++ WF +G+  +  +   ++    D G
Sbjct: 945  PIFDKRLK-HFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGD-G 1000

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
              +L I+   + D G YT  A N  G      +I+CS    +V    +   ++       
Sbjct: 1001 TCSLHIESTTSDDDGNYTIMAANPQG------RISCSGHL-MVQSLPIRSRLTSAGQSHR 1053

Query: 3812 ERGRISDAPKEEPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
             R R+ +  KE P+      P F+         E    R +C+V     P+L   W  NG
Sbjct: 1054 GRSRVQERDKE-PLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNG 1110

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS-----CKK 3923
            + +LP       V + G  SL I  +   D+G Y C A N  G++     +S      KK
Sbjct: 1111 QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK 1170

Query: 3924 LPDII--LQN-QVPRG 3936
             P I+  LQN  VP G
Sbjct: 1171 APVILEKLQNCGVPEG 1186



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 70/266 (26%), Positives = 119/266 (44%), Gaps = 30/266 (11%)

Query: 1168 QIEEISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            Q +EI   K   P+F + L +   V+EG  +   C++  +G P  +V WF +G+ ++  +
Sbjct: 933  QHDEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRN 989

Query: 1225 ---RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE---RSDIVTD 1278
               + +   D G  +L I   TS D G YT+ A N  G    S  + V     RS + + 
Sbjct: 990  EHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSA 1048

Query: 1279 TQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVG 1338
             Q+ +   ++Q  +    + +  R        P F +A  ++   EG    L+C++   G
Sbjct: 1049 GQSHRGRSRVQERDKEPLQERFFR--------PHFLQAPGDMVAHEGRLCRLDCKVS--G 1098

Query: 1339 DQTMRVEWFCNGKPI--KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                 + W  NG+P+     H+     E    +L +  +   D+G Y C ATN+ G+   
Sbjct: 1099 LPPPELTWLLNGQPVLPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSF 1157

Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQ 1422
            S  L V+AK+      + P  LEK+Q
Sbjct: 1158 SLELSVVAKE----VKKAPVILEKLQ 1179



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 63/230 (27%), Positives = 95/230 (41%), Gaps = 15/230 (6%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI-KTGHRFRPAYEFDYV 1368
            AP F + L +    EG+ V   C++  VG    +V WF +GK I K     +   E D  
Sbjct: 944  APIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001

Query: 1369 -ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
             +L + S   +D G YT  A N  G    S  L V   + L + S+  S  +  +     
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQSHRGRSRV 1058

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
                K  + +     +P F+  P  +    EG+    +CK+  +    L   W  NGQPV
Sbjct: 1059 QERDKEPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 1113

Query: 1488 T--IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
                 H+   + + G  +L I  L   D+G Y C A N  G +  S  L+
Sbjct: 1114 LPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELS 1162



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 61/237 (25%), Positives = 100/237 (42%), Gaps = 13/237 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694
            P F   LK     EG  + F  +I  VG P  K+ W K+G+ I   +    + R G    
Sbjct: 945  PIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTC 1002

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            SL + S    D G YT  A +  G       L V       R +   ++ +   ++++  
Sbjct: 1003 SLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERD 1062

Query: 755  KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT 814
            K    E ++E+   RP F++   D+    EGR    + +++ +  P +   W  +G+P+ 
Sbjct: 1063 K----EPLQERFF-RPHFLQAPGDM-VAHEGRLCRLDCKVSGLPPPELT--WLLNGQPVL 1114

Query: 815  A-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
              +S    +   G  SL I  L   DAG+Y   A NK G+   +  + V A+    A
Sbjct: 1115 PDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKA 1171



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 7/105 (6%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F K+ Q+   +EG++  F+CRV G P P+V W+     I D  + +IL  +  + A 
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493

Query: 450 ------LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
                 L+I  V   DSG  TC A NK G  +   +L+V   E +
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 3/98 (3%)

Query: 3688 EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            E+    PPRFT +++   +VPEG  V  DC V  VG P  ++ W+  G+       +H +
Sbjct: 262  EEPLGQPPRFTQKLRSR-EVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIV 318

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                  +L I   +  D G Y+C A+N +G+ +T+A+I
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 62/244 (25%), Positives = 97/244 (39%), Gaps = 13/244 (5%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            LE+    ES +  +  EIP       P+F + L++   + EG    F C++  VG P  K
Sbjct: 920  LERTPVDESDDEIQHDEIPTGKCIA-PIFDKRLKHF-RVTEGSPVTFTCKI--VGIPVPK 975

Query: 2410 VEWFRNEKLIEDSSRITKTH--DFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            V WF++ K I   +   K      G  S+ I     +D+G Y   A+N  G         
Sbjct: 976  VYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 1035

Query: 2468 XXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAH 2527
                  + + ++     +  +   +  ER  E     F +P F Q   G     EG+   
Sbjct: 1036 VQS---LPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQA-PGDMVAHEGRLCR 1091

Query: 2528 YEARVVPVGDPSLRFEWYINGVE-LKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAI 2586
             + +V  +  P L   W +NG   L   S      + G  +L I+ +   DAG Y C A 
Sbjct: 1092 LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIAT 1149

Query: 2587 NRAG 2590
            N+ G
Sbjct: 1150 NKTG 1153



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 60/226 (26%), Positives = 102/226 (45%), Gaps = 19/226 (8%)

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS---RVKTINDFGFVILEIGGVYQR 3625
            ++E S   F C+++ +     +V WF +GK +   +   +++   D G   L I      
Sbjct: 956  VTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSD 1012

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEI 3685
            D G YT  A N  G  + S  L V   Q + +  +L S  +S      +    + +R++ 
Sbjct: 1013 DDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQS-----HRGRSRVQERDKE 1064

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP-FATGSRV 3744
             ++ E+   P F ++   ++   EG     DC+V   G P   + W  NG+P     S  
Sbjct: 1065 PLQ-ERFFRPHF-LQAPGDMVAHEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHK 1120

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              + + G  +L ID +  RDAG Y C ATNK G  + + +++  AK
Sbjct: 1121 MLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 1166



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 74/303 (24%), Positives = 115/303 (37%), Gaps = 46/303 (15%)

Query: 3413 EEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF 3472
            EE  G+ P FT  L + E + EG     +  +     P  +V WY  GK L+        
Sbjct: 262  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIV 318

Query: 3473 CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTI 3532
                   L I+  + ED+G Y C A N YG   T+A + ++G  +   E    K     I
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRI 378

Query: 3533 DK---IAALEGYSGTVDTLTPEAE------------------------SGNP----PEFT 3561
             K   +++    S  +    P+A+                         G P    P FT
Sbjct: 379  QKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFT 438

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG-----KP---LLTGSRVKTINDFG 3613
                +L  SE     FECR+      S +VEW+  G      P   +L            
Sbjct: 439  KMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEE 496

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ 3673
               L I  V+  D+G +TC A+N++G  +   +L V+G + +     L  H  + T ++ 
Sbjct: 497  ICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSL--HSANSTTNLA 554

Query: 3674 KLE 3676
             +E
Sbjct: 555  AIE 557



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 60/242 (24%), Positives = 103/242 (42%), Gaps = 17/242 (7%)

Query: 1571 DEVTTQ---APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            DE+ T    API    LK+  + EG    F  +++ +     KV W+ + K +   +   
Sbjct: 935  DEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIP--VPKVYWFKDGKQISKRNEHC 992

Query: 1628 ETNNFG--FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
            +    G    +L I S   +D G YT  A N  G    SG  +V   +S+ + S+   A 
Sbjct: 993  KMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAG 1049

Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
                      +  +   Q+      P F     D+   E +    + ++  +  P+L   
Sbjct: 1050 QSHRGRSRVQERDKEPLQERFF--RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL--T 1105

Query: 1746 WLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            WL NG P+  +AS+++  + + G  +L +  +   D+GTY C A N+ G+   S  L V 
Sbjct: 1106 WLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVV 1164

Query: 1804 SK 1805
            +K
Sbjct: 1165 AK 1166



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 40/122 (32%), Positives = 57/122 (46%), Gaps = 8/122 (6%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTYT 4570
            PP FT   ++  V  G  V+LD  V G  P  V W   GK+++  PDI   I++    ++
Sbjct: 268  PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIH--IVQAGNLHS 325

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAEC----VVSLPATKDKPKPQTKAANAPPEII 4626
            L I EA+ +D+G+Y C A N  G     AE     V S  +  D  K +      P E+ 
Sbjct: 326  LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVS 385

Query: 4627 EP 4628
             P
Sbjct: 386  SP 387



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 9/145 (6%)

Query: 3146 GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG 3205
            GQ PRFT  +++ E + +G     +C VV +  P  ++ WY  G+ + +S  I  V    
Sbjct: 266  GQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQAGN 322

Query: 3206 FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELES 3265
               L IA     D+G Y C A N YG D T A I   G     + S   +      E+  
Sbjct: 323  LHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG-----VSSSDSEGDPNKEEMNR 377

Query: 3266 LQGAQQ-QTPSTPSAEPPKFITQIQ 3289
            +Q   +  +P T SA  P  + Q Q
Sbjct: 378  IQKPNEVSSPPTTSAVIPPAVPQAQ 402



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 49/164 (29%), Positives = 74/164 (45%), Gaps = 12/164 (7%)

Query: 2235 EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT 2294
            EEP   PPRF  +LR +  V EG     +C V  +  P +R  +Y  GK L+++   HI 
Sbjct: 262  EEPLGQPPRFTQKLR-SREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 2295 FDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  SL I     ED G YS  A N  G  T + S  +  +G   S+S+     E++ 
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYG--TDSTSAEIYIEGVSSSDSEGDPNKEEMN 376

Query: 2355 ELE-----SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQT 2393
             ++     S+ P     IP  V + + +  QP   +  IQ+ Q+
Sbjct: 377  RIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQP--RVATIQQCQS 418



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 6/159 (3%)

Query: 4343 QKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE 4402
            ++  +P P  +     EV+ A ++Q  K     +E  +  +     +    +       E
Sbjct: 207  ERSSVPIPIPADTRDNEVNHALEQQEAKR----REAEQAASEAAGGDTTPGSSPSSLYYE 262

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
             P+   +PP FT+K++   V E  + + +    G P P ++WY E   ++NSPD  I   
Sbjct: 263  EPL--GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQA 320

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
                 L I + F ED+  ++  A N  GT   SA + +E
Sbjct: 321  GNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 36/135 (26%), Positives = 60/135 (44%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+  QK R+ ++ EG   Q    + G P P+V W+  G+ L NS    I+   N  +L 
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +    + D+G Y+  A N  G   TS  + +E  + S  +   ++   +  Q+  E    
Sbjct: 328 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSP 387

Query: 385 ISEKALAPQFVKVCQ 399
            +  A+ P  V   Q
Sbjct: 388 PTTSAVIPPAVPQAQ 402



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
            EEP+   PP+F  +++S  V E   V+ +C V     P++R  WY  GK L +      V
Sbjct: 262  EEPL-GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
                  SL I   + ED+G Y C A N +G D T A I
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 8/93 (8%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--------L 4778
            L+++   EGQ   F+ ++     P ++W REG LI ++PDF+++ +   ++        L
Sbjct: 441  LQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTL 500

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +I   + ED+G FTC A+   G V + A+L V+
Sbjct: 501  VIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVR 533



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 15/222 (6%)

Query: 3985 LVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY--DFGYVAMNFGWVYPED 4042
            + E     F C++  VG P  KV WF +GK +  +N    +     G  +++      +D
Sbjct: 956  VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDD 1013

Query: 4043 SGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             G Y   A N  G       +     P       +   + S  +     +  Q   ++ +
Sbjct: 1014 DGNYTIMAANPQGRISCSGHLMVQSLP-------IRSRLTSAGQSHRGRSRVQERDKEPL 1066

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY- 4161
            +E   R  P F+  P  +   EG   R  C+V+G P P + WLLNG  ++  + +K+   
Sbjct: 1067 QERFFR--PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 1124

Query: 4162 -DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
              G++   I    Q D G  + I             L V+ +
Sbjct: 1125 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 1166



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            + P+F + +++ EV EG  V L+  +  +  P +R  WYC G+ ++              
Sbjct: 267  QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIVQAGNLH 324

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD-TLDEQRLKKIQELEKY 2094
            +L I  A+ EDTG Y C A+N  G   T++ + ++  S    +   +++ + +IQ+  + 
Sbjct: 325  SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEV 384

Query: 2095 ERP 2097
              P
Sbjct: 385  SSP 387



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 68/275 (24%), Positives = 113/275 (41%), Gaps = 26/275 (9%)

Query: 751  EDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG 810
            E   + QH E I       P F + L+    + EG    F  ++  +  P  +V W+KDG
Sbjct: 927  ESDDEIQHDE-IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGI--PVPKVYWFKDG 982

Query: 811  RPITASSRITSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
            + I+  +    +   G    SL+I    ++D G+YT+ A N  G    +  + V +    
Sbjct: 983  KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---- 1038

Query: 869  TADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
                 +P + R +                    + E   +P F     D ++  EG    
Sbjct: 1039 -----LPIRSR-LTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVA-HEGRLCR 1091

Query: 929  FEARLEPIGDSTLRVEWLKDGRPV--EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
             + ++  +    L   WL +G+PV  +AS ++      G  +L I  +T  DAG Y C A
Sbjct: 1092 LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVR-ETGVHSLLIDPLTQRDAGTYKCIA 1148

Query: 987  YNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             N  GQ + S  L++V K+      + P  LEK+Q
Sbjct: 1149 TNKTGQNSFSLELSVVAKE----VKKAPVILEKLQ 1179



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 59/237 (24%), Positives = 95/237 (40%), Gaps = 19/237 (8%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVS 2832
            +F   L +    EG  + F C +     P  K+ WF + K +     +           S
Sbjct: 946  IFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 1003

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE 2892
            L I  T  +D G YT  A N +G  + SG L            Q    ++ L +  Q+  
Sbjct: 1004 LHIESTTSDDDGNYTIMAANPQGRISCSGHLM----------VQSLPIRSRLTSAGQSHR 1053

Query: 2893 ARLAKGRRPSVPDTE-YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNG 2951
             R     R   P  E + +P + +    +    EG++  L+ +V     P+L   W  NG
Sbjct: 1054 GRSRVQERDKEPLQERFFRPHF-LQAPGDMVAHEGRLCRLDCKVSGLPPPEL--TWLLNG 1110

Query: 2952 K-VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
            + VL   S   L  + G  +L +  + +RD+G Y C A NK G+   S  +   +K+
Sbjct: 1111 QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P+F++ L + E  EGT V L+C +  VG    +V W+C GK ++           +  
Sbjct: 267  QPPRFTQKLRSREVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQAGNLH 324

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L +   + ED+G Y+C A+N  G   TS  + +
Sbjct: 325  SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 8/103 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
           K  + AP F +    L+  EG+ VV   R  G P+P++ W ++G  I  +P+ RI     
Sbjct: 429 KPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKP 488

Query: 545 AS--------TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            S        TL I    A D+  + CTA N  G+ ++ A+L+
Sbjct: 489 RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLH 531



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 7/161 (4%)

Query: 3965 YDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTP 4024
            Y+    QPPRF  +++S+      E T+ +     VG P  +V W+  GK L +      
Sbjct: 261  YEEPLGQPPRFTQKLRSREV---PEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI 317

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSI 4084
            +      ++     + ED+G Y C A+N+YG D T A I   G      DS+   + + +
Sbjct: 318  VQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEM 375

Query: 4085 EKIRE-MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEE 4124
             +I++  E S   T   V+  +  +   + V+ P   T+++
Sbjct: 376  NRIQKPNEVSSPPTTSAVIPPAVPQAQHL-VAQPRVATIQQ 415



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 10/110 (9%)

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR------ 1360
            ++ AP F++ L N+   EG  V  ECR++  G  + +VEW+  G  I+    FR      
Sbjct: 431  IIAAPVFTKMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKP 488

Query: 1361 --PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
               A   +   L +  V+ EDSG +TC A+N+ G   +   L V   +DL
Sbjct: 489  RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 37/91 (40%), Positives = 49/91 (53%), Gaps = 11/91 (12%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKTHDFGY 2433
            PVFT+ LQN+ +  EGQ   F+CR+   G P+ KVEW+R   LIEDS   RI +      
Sbjct: 435  PVFTKMLQNL-SASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 2434 V------SMTISHVRDEDEGVYMCRASNLLG 2458
                   ++ I+ V  ED G + C ASN  G
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 23/238 (9%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM---RHSTRIKTVSDFG 3205
            P F   +++   + +G    F C +V +  P  K+ W+ +G+ +       +++   D G
Sbjct: 945  PIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCKMRREGD-G 1000

Query: 3206 FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDS-LAKIRELE 3264
               L I  T + D G Y   A N  G       I+C   G + ++SL   S L    +  
Sbjct: 1001 TCSLHIESTTSDDDGNYTIMAANPQGR------ISC--SGHLMVQSLPIRSRLTSAGQSH 1052

Query: 3265 SLQGAQQQTPSTPSAEP---PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321
              +   Q+    P  E    P F+    D+    EG+    + ++  +  P+L   W  N
Sbjct: 1053 RGRSRVQERDKEPLQERFFRPHFLQAPGDMVAH-EGRLCRLDCKVSGLPPPELT--WLLN 1109

Query: 3322 GKK-LPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            G+  LP         + G+  L I    + ++G Y+C+ATNK G++S    L   +KE
Sbjct: 1110 GQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 57/214 (26%), Positives = 98/214 (45%), Gaps = 25/214 (11%)

Query: 1077 VEWYFNGKQITSAN---RIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            V W+ +GKQI+  N   +++   D G  +L I S  ++D G YT++A N  G    S  +
Sbjct: 976  VYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 1034

Query: 1134 TVET---RSSIDTS-SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPV 1189
             V++   RS + ++   HRG   ++R  E  K  EP+ +       +P F+Q        
Sbjct: 1035 MVQSLPIRSRLTSAGQSHRG---RSRVQERDK--EPLQE----RFFRPHFLQ-APGDMVA 1084

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGFVALDIIHATSADTG 1248
             EG+   L+C++   G P   + W  NG+ V   +  K    + G  +L I   T  D G
Sbjct: 1085 HEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAG 1142

Query: 1249 EYTVRAVNHLG----SAHTSAIVRVIERSDIVTD 1278
             Y   A N  G    S   S + + ++++ ++ +
Sbjct: 1143 TYKCIATNKTGQNSFSLELSVVAKEVKKAPVILE 1176



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 27/85 (31%), Positives = 42/85 (49%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            LR   V EG   Q    +     P ++W  EG  +  +PD  ++  GN   L I   +EE
Sbjct: 275  LRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEE 334

Query: 4787 DTGTFTCRATTAAGQVETSAKLVVK 4811
            DTG ++C A+   G   TSA++ ++
Sbjct: 335  DTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 34/221 (15%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT--THNHTTL 323
            P   Q P +    EG   +   ++SG P P +TW  NGQ ++    H+++   T  H+ L
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                TQ+ D+G Y         CI T+                     T       E  +
Sbjct: 1133 IDPLTQR-DAGTYK--------CIATNK--------------------TGQNSFSLELSV 1163

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
               E   AP  ++  Q+  V EG   R +CRV G P P V ++  D +       +I ++
Sbjct: 1164 VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMP-PPVFYWKKDNETIPCTRERISMH 1222

Query: 444  E--SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            +  +G   L+I     SD+G  T  A+N++G  +   RL++
Sbjct: 1223 QDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 33/112 (29%), Positives = 49/112 (43%)

Query: 50   TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
            T V+ S D         G+   PIF++  K+ R  +G    F  K+ G P P V W +  
Sbjct: 923  TPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDG 982

Query: 110  APLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              + + N++     E  G  SL I+     D+G YT  A N  G   CS ++
Sbjct: 983  KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 1034



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 12/145 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG--- 3751
            P FT ++  N+   EG  V F+CRV+  G P+ +++W+  G           L       
Sbjct: 435  PVFT-KMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 3752 -----FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
                    L I  ++A D+G +TC A+NK+G+ ++ A++      D+     L    S  
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTT 551

Query: 3807 KIKELERGRISDAPKEEPIVSTPPK 3831
             +  +E  + S    E P V  PPK
Sbjct: 552  NLAAIE-PQPSPPHSEPPSVEQPPK 575



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 104/250 (41%), Gaps = 22/250 (8%)

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276
            LE+    E+       E+   K   P F   L+    V EG    F C++  +  P  ++
Sbjct: 920  LERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KV 976

Query: 2277 EFYHNGKALQSAARFHITF---DFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAIS 2331
             ++ +GK + S    H        G  SL I+    +D G Y++ A N  G   C+  + 
Sbjct: 977  YWFKDGKQI-SKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 1035

Query: 2332 M-TVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390
            + ++  +  + S  Q   G  +++E +  EP +           RP F Q   ++    E
Sbjct: 1036 VQSLPIRSRLTSAGQSHRGRSRVQERDK-EPLQERFF-------RPHFLQAPGDMV-AHE 1086

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            G+    DC++   G P  ++ W  N + ++ D+S      + G  S+ I  +   D G Y
Sbjct: 1087 GRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 1144

Query: 2450 MCRASNLLGE 2459
             C A+N  G+
Sbjct: 1145 KCIATNKTGQ 1154



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 57/231 (24%), Positives = 89/231 (38%), Gaps = 13/231 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG---AR 2690
            + TG   APIF   LK + ++ EG  V    ++     P  K+ WFK+G  ++      +
Sbjct: 937  IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCK 993

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            ++   D G  +L I S  +DD G YT  A N  G    +  + ++     +   L     
Sbjct: 994  MRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSAGQ 1050

Query: 2751 DRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWF 2810
               G                     F+    ++V  EG     +C V  S  P  ++ W 
Sbjct: 1051 SHRGR-SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV--SGLPPPELTWL 1107

Query: 2811 FNNKP-LPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
             N +P LP  +      +    SL I    + D+G Y C ATN  G  + S
Sbjct: 1108 LNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFS 1158



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 4/117 (3%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            Q P FTQ L++ + + EG     DC  I VG P  +V W+   K +E+S  I        
Sbjct: 267  QPPRFTQKLRSRE-VPEGTRVQLDC--IVVGIPPPQVRWYCEGKELENSPDIHIVQAGNL 323

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE-TQHPEGMKKIQK 2489
             S+TI+   +ED G Y C ASN+ G                  E   + E M +IQK
Sbjct: 324  HSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQK 380



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 14/151 (9%)

Query: 1678 ESQHEGALPR---LNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARL 1734
            ++QH  A PR   + Q +  + Y +     + I  APVFT  ++++  +E Q   FE R+
Sbjct: 400  QAQHLVAQPRVATIQQCQSPTNYLQ-GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRV 458

Query: 1735 IPVGDPKLRVEWLRNGVPIEAS-------NRLTTMHDFGYV-ALNMKYVNPEDSGTYTCR 1786
               G P  +VEW R G  IE S        +  +M +   +  L +  V  EDSG +TC 
Sbjct: 459  --KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCT 516

Query: 1787 AINELGEAVTSSTLFVQSKASLQLESQHESA 1817
            A N+ G   + + L V+    L       SA
Sbjct: 517  ASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 547



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIR----- 4559
            G+  I  P FT   QN++ + GQLV  + +V G     V W + G  ++  PD R     
Sbjct: 428  GKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKK 487

Query: 4560 -NKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
               + E +   TL+I E + +DSG + C A N  G
Sbjct: 488  PRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 43/149 (28%), Positives = 62/149 (41%), Gaps = 13/149 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APVFT  L N+ +  EG+   FE R+     P  KVEWY  G  ++    FR        
Sbjct: 434  APVFTKMLQNL-SASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRS 490

Query: 3479 ILE--------ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530
            + E        I+  + EDSG + C A N YG   + A + V+G  ++     L      
Sbjct: 491  MAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANST 550

Query: 3531 TIDKIAALEGYSGTVDTLTPEAESGNPPE 3559
            T   +AA+E       +  P  E    P+
Sbjct: 551  T--NLAAIEPQPSPPHSEPPSVEQPPKPK 577



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P  +PP+F  +++   ++ EG     +  +V +  P  +V W+  GK+L +         
Sbjct: 264  PLGQPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQA 320

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              +  L I   +EE++G Y C A+N  G DST A +
Sbjct: 321  GNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 3/82 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HAL 450
           P+F +  + R+V EG   + DC V G P P+V W+   +++ +  +  I + ++GN H+L
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELEN--SPDIHIVQAGNLHSL 326

Query: 451 MITNVTLSDSGVVTCVARNKSG 472
            I      D+G  +C A N  G
Sbjct: 327 TIAEAFEEDTGRYSCFASNIYG 348



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 11/97 (11%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            +PI++ P  F   +++ +  E + V FECRV+    PK  +EWYR G L+     +R + 
Sbjct: 429  KPIIAAPV-FTKMLQNLSASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQ 485

Query: 3883 DMG--------FVSLDILYVYAEDSGEYICRAVNDFG 3911
                         +L I  V+AEDSG + C A N +G
Sbjct: 486  KKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 73/303 (24%), Positives = 116/303 (38%), Gaps = 47/303 (15%)

Query: 2870 NIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYP--KPEWIIPIAAEHQLVEGQ 2927
            N   + Q  + +   +A  +A       G  PS    E P  +P          ++ EG 
Sbjct: 225  NHALEQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGT 284

Query: 2928 VLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCK 2987
             + L+  V     P  ++ WY  GK LE      +       +L + + +E D+G Y+C 
Sbjct: 285  RVQLDCIVV--GIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCF 342

Query: 2988 AYNKRGEAFTSSTVY---CTSKDN-------LIERTQHPKGTE-----------GLEKIQ 3026
            A N  G   TS+ +Y    +S D+        + R Q P                + + Q
Sbjct: 343  ASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQ 402

Query: 3027 NLEDSLRKEPGQQPDDDT-------GRP----PEFTTVFKDIVDISEGQIAHYEASLIPT 3075
            +L    R    QQ    T       G+P    P FT + +++   SEGQ+  +E  +   
Sbjct: 403  HLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNL-SASEGQLVVFECRV--K 459

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVY--------AFGMVVLEILGTKTTDSGTYSCRATN 3127
            G  S  +EW+  G  IE S   R +            +  L I      DSG ++C A+N
Sbjct: 460  GAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASN 519

Query: 3128 KWG 3130
            K+G
Sbjct: 520  KYG 522



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 5/123 (4%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            E  + Q PRF  +L    ++ EG     +C +   P P +R  WY  GK L++       
Sbjct: 262  EEPLGQPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
                  +L I   + ED+G Y+C A N  G   +S  + ++   S   DS+ +   E++ 
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMN 376

Query: 1957 YLE 1959
             ++
Sbjct: 377  RIQ 379



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 18/143 (12%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG--- 3205
            P FT  +QN+    +GQ   FEC V     P  K+EWY  G  +  S   + +       
Sbjct: 435  PVFTKMLQNLSA-SEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 3206 -----FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD-SLAK 3259
                    L IA     DSG + C A NKYG   + A ++  G      E L  + SL  
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGN-----EDLSNNGSLHS 546

Query: 3260 IRELESLQGAQQQTPSTPSAEPP 3282
                 +L   + Q PS P +EPP
Sbjct: 547  ANSTTNLAAIEPQ-PSPPHSEPP 568



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 21/142 (14%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-------- 2160
            PVF   L +L +  EG    FECRV+    P   ++W+  G  I     +R         
Sbjct: 435  PVFTKMLQNL-SASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKI 2220
                    L I   +AEDSG + C A+NK G   +   L V G+ ++       NG    
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL-----SNNG---- 542

Query: 2221 RQLEAQGHSTRIEVEEPKISPP 2242
              L +   +T +   EP+ SPP
Sbjct: 543  -SLHSANSTTNLAAIEPQPSPP 563



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 10/99 (10%)

Query: 64  GRPGEP--SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE------- 114
           G  G+P  + P+F ++ +N   ++G    FE +++G P+P V W R +  L+E       
Sbjct: 425 GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYR-EGTLIEDSPDFRI 483

Query: 115 CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
             K      E     +L+I ++   D G +TCTA N+YG
Sbjct: 484 LQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 10/105 (9%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--------STH 2826
            VF   L N+   EG  + FEC V+ +  P  K+EW+     +     ++           
Sbjct: 436  VFTKMLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAE 493

Query: 2827 DFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
                 +L I   + EDSG +TC A+N  G+ ++   L   G++++
Sbjct: 494  PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+V +EG+  +   +++    P + WL  G  ++P+     ++ E     LLI    + D
Sbjct: 1081 DMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRD 1140

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             GT+ C AT   GQ   S +L V +K
Sbjct: 1141 AGTYKCIATNKTGQNSFSLELSVVAK 1166



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 8/108 (7%)

Query: 3036 PGQQP-----DDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090
            PG  P     ++  G+PP FT   +   ++ EG     +   I  G     + W+  GK 
Sbjct: 252  PGSSPSSLYYEEPLGQPPRFTQKLRSR-EVPEG--TRVQLDCIVVGIPPPQVRWYCEGKE 308

Query: 3091 IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            +E S  I  V A  +  L I      D+G YSC A+N +G    S ++
Sbjct: 309  LENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 63/232 (27%), Positives = 90/232 (38%), Gaps = 17/232 (7%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH-- 1491
            D I     I P F  R K    V EG  V F CK+  +     KV WFK+G+ ++  +  
Sbjct: 935  DEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEH 991

Query: 1492 -RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             + R   D G  +L I    ++D G YT  A N  G    S  L  +S    +RS    A
Sbjct: 992  CKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSA 1048

Query: 1551 GLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL 1609
            G    Q    RS+    D    +     P    +  ++   EG+    + ++  +    L
Sbjct: 1049 G----QSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL 1104

Query: 1610 KVEWYHNNKP-LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
               W  N +P L   S        G  +L I      D+GTY C A N  G+
Sbjct: 1105 --TWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ 1154



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL--------TSDFGFVTLDLVDV 2976
            EGQ++  E +V  K  P  K+EWY  G ++E    F++               TL + +V
Sbjct: 448  EGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 505

Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL 3009
            +  DSG +TC A NK G   + + ++    ++L
Sbjct: 506  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 7/160 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L +    EG  +  +C V     P  ++ W+   K L +          +  SL I
Sbjct: 271  FTQKLRSREVPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQAGNLHSLTI 328

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               +EED+G Y+C A+N  G+ +TS  +   G  +   D++    K  +  +++  E   
Sbjct: 329  AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMNRIQKPNEVSS 386

Query: 2896 AKGRRPSVPDTEYPKPEWII--PIAAEHQLVEGQVLHLEG 2933
                   +P    P+ + ++  P  A  Q  +    +L+G
Sbjct: 387  PPTTSAVIPPA-VPQAQHLVAQPRVATIQQCQSPTNYLQG 425



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGD 128
            +P I E++ +N    +G   + E ++ G P PV  W +K    + C +  +  + + TG 
Sbjct: 1171 APVILEKL-QNCGVPEGHPVRLECRVIGMPPPVFYW-KKDNETIPCTRERISMHQDTTGY 1228

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
              LLI+     D G YT +A+N+ G   C+
Sbjct: 1229 ACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 2097 PKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            P  +  E+P GQ P F   L S E + EG R   +C V  I  P   + W+  G+++   
Sbjct: 256  PSSLYYEEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPPQ--VRWYCEGKELENS 312

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                        +L I   + ED+G Y C A+N  G    +  + + G
Sbjct: 313  PDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG 360



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 630 EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
           E+ +  PP+F   L+S    EG ++  +  +  VG P  ++ W   G+ +E S     + 
Sbjct: 262 EEPLGQPPRFTQKLRSREVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQ 319

Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
                SL +     +D+G Y+C A +  G   T A +++
Sbjct: 320 AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            +E +   PRF  + +S E V EG  V  +C +  +     +V W+  G+ +        +
Sbjct: 262  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIV 318

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                  +L I +   ED+G Y+C A N+ GTD  S  +
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 11/132 (8%)

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
            +A I++ +S     Q     P    P F   +Q+++   EGQ   FE R+     P  KV
Sbjct: 410  VATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSAS-EGQLVVFECRVKGAPSP--KV 466

Query: 3317 EWFYNGKKLPHGHRYRTFHDFG--------IVILDILYCYEENSGEYECVATNKLGRDST 3368
            EW+  G  +     +R              I  L I   + E+SG + C A+NK G  S+
Sbjct: 467  EWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSS 526

Query: 3369 KANLKCTSKENL 3380
             A L     E+L
Sbjct: 527  IAQLHVRGNEDL 538



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 10/93 (10%)

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG--------YVALDIIDL 1509
            EGQ V FEC+++       KVEW++ G  +     FR +               L I ++
Sbjct: 448  EGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 505

Query: 1510 IAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
             AEDSG +TC A N  GT     +L  R   D+
Sbjct: 506  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF-ATGS 3742
            E+++  ++       +E   N  VPEG PV  +CRV  +G P     W  +      T  
Sbjct: 1160 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV--IGMPPPVFYWKKDNETIPCTRE 1217

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            R+    D  G+  L I      DAG YT  A N+ G  + TA++   A+
Sbjct: 1218 RISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 1266



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 4/140 (2%)

Query: 1571 DEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +E   Q P  T  L++ E+ EG R   +   I V     +V WY   K L++        
Sbjct: 262  EEPLGQPPRFTQKLRSREVPEGTRVQLD--CIVVGIPPPQVRWYCEGKELENSPDIHIVQ 319

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQ 1690
                 +L I     ED+G Y+C A N  G   TS    +    S   +S+ +     +N+
Sbjct: 320  AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMNR 377

Query: 1691 LEDTSKYQRHSAQDEVITQA 1710
            ++  ++         VI  A
Sbjct: 378  IQKPNEVSSPPTTSAVIPPA 397



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 6/122 (4%)

Query: 1170 EEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            EE     P F Q L +   V EG  + L+C +  +G P  +V W+  G+ +         
Sbjct: 262  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIV 318

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV--IERSDIVTDTQNEQAIEQ 1287
                  +L I  A   DTG Y+  A N  G+  TSA + +  +  SD   D  N++ + +
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD-PNKEEMNR 377

Query: 1288 IQ 1289
            IQ
Sbjct: 378  IQ 379



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 2632 MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691
            ++ +  + Q P FT  L+S + + EG  V L+  V     P  ++ W+  G  L     +
Sbjct: 259  LYYEEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDI 315

Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
                   L +L+I     +D+G Y+C A+N+ G   ++A I IE
Sbjct: 316  HIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E  + Q PRF   L+ + ++ EG     +  V         V WY  GK++ ++  I   
Sbjct: 262  EEPLGQPPRFTQKLR-SREVPEGTRVQLDCIVVGIPP--PQVRWYCEGKELENSPDIHIV 318

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
                  +L IA    ED+G Y+  A N  G    SA + +E  SS D+
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDS 366



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 6/123 (4%)

Query: 763 EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822
           EE   Q P+F + L+   E+ EG     +  +  +  P +R  WY +G+ +  S  I  +
Sbjct: 262 EEPLGQPPRFTQKLRSR-EVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP--EQRRY 880
                 SL I     ED G Y+  A N  G   ++A I +   S+  ++ G P  E+   
Sbjct: 319 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSE-GDPNKEEMNR 377

Query: 881 IEK 883
           I+K
Sbjct: 378 IQK 380



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            + ++  + P  +  LQ+ G + EG     E ++  +  P     W KD   I  +    S
Sbjct: 1164 VAKEVKKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERIS 1220

Query: 822  IFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            +     GY  L I   +  DAG YT+ A N+ G    TA + + A+
Sbjct: 1221 MHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 1266



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 11/91 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-------- 2559
            P+FT++L   S   EGQ   +E RV   G PS + EWY  G  ++    FR         
Sbjct: 435  PVFTKMLQNLSAS-EGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 2560 THDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   TL I  V A D+G + C A N+ G
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G   + + K+ G P P ++W     P++    + M   E TG  SLLI  +   D G Y
Sbjct: 1086 EGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRE-TGVHSLLIDPLTQRDAGTY 1144

Query: 145  TCTARNQYGE 154
             C A N+ G+
Sbjct: 1145 KCIATNKTGQ 1154



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--------TE 1628
            AP+ T  L+N+   EGQ   FE R+      + KVEWY     ++    F        + 
Sbjct: 434  APVFTKMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
                    L I     EDSG +TC A N  G    S IA +H
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG--TVSSIAQLH 531



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            PVF  +   ++  EG+   F CRV G P P+V W   G  I +   +++
Sbjct: 435  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRI 483



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 4/88 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-- 1764
            + +APV    +++  V E      E R+I  G P     W ++   I  +    +MH   
Sbjct: 1168 VKKAPVILEKLQNCGVPEGHPVRLECRVI--GMPPPVFYWKKDNETIPCTRERISMHQDT 1225

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELG 1792
             GY  L ++     D+G YT  A NE G
Sbjct: 1226 TGYACLLIQPAKKSDAGWYTLSAKNEAG 1253



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 1/84 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            +P  +  E     PP F     +  V EG   +  C V G P P+V W   G  + N   
Sbjct: 255  SPSSLYYEEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPD 314

Query: 4157 YKLTYDGMYH-FDIPKTRQYDTGK 4179
              +   G  H   I +  + DTG+
Sbjct: 315  IHIVQAGNLHSLTIAEAFEEDTGR 338



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/101 (22%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ--------RLINSNKHEI 314
           ++ P   +  +N    EG    F+ ++ G P P+V W++ G         R++      +
Sbjct: 432 IAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
                  TL +      DSG +T  A N  G + +   L V
Sbjct: 492 AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT-VGSRFKTYYDF 1232
            K  PV ++ L N   V EG  + LECR+  M  P     W  +  ++     R   + D 
Sbjct: 1169 KKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERISMHQDT 1225

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             G+  L I  A  +D G YT+ A N  G    +A
Sbjct: 1226 TGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTA 1259



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 3/95 (3%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            Q P F   ++ +  + EG     +  +  +G    +V W  +G+ +E S  I        
Sbjct: 267  QPPRFTQKLRSR-EVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQAGNL 323

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +LTI      D G Y+C A N  G  +TSA + I
Sbjct: 324  HSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 37/164 (22%), Positives = 59/164 (35%), Gaps = 11/164 (6%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY---KLTYDGMYHF 4167
            P+F        V EG    F C++ G P P+V W  +G  I   + +   +   DG    
Sbjct: 945  PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRT 4227
             I  T   D G   ++             L V  +    R  L +A +     +   +R 
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV--QSLPIRSRLTSAGQSHRGRSRVQERD 1062

Query: 4228 ETELEKTFEERQVLQRQG-VIDH-----RPELKPKVIKEPETEW 4265
            +  L++ F     LQ  G ++ H     R + K   +  PE  W
Sbjct: 1063 KEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTW 1106



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            + P FTQ L    E+ EG     +  VV +  P +R  WY  G EL+             
Sbjct: 267  QPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIVQAGNL 323

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I      D G Y C A N  G
Sbjct: 324  HSLTIAEAFEEDTGRYSCFASNIYG 348



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129
           PP F Q  ++    +G   + +  + G P P V W  +   L       +    Q G++ 
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI---VQAGNLH 324

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           SL I +    D G Y+C A N YG    S  I  EG
Sbjct: 325 SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG 360



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG-----KP---LLHKNRFTP 4024
            P F   +Q+  S  E +   FEC++   G P+ KVEW+  G      P   +L K   + 
Sbjct: 435  PVFTKMLQN-LSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQL 4077
                    +    V+ EDSG + C A+N YG   + A +   G   +  +  L
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSL 544



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY------ 1230
            PVF + L N    SEG+ +  ECR++  G P+ +VEW+  G  +     F+         
Sbjct: 435  PVFTKMLQNLS-ASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 1231 --DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
                    L I    + D+G +T  A N  G+  + A + V    D+
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538


>AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein
           myopalladin, 145 kDa (MYOP) protein.
          Length = 1045

 Score =  226 bits (553), Expect = 1e-57
 Identities = 124/364 (34%), Positives = 200/364 (54%), Gaps = 9/364 (2%)

Query: 220 DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQE 279
           ++K+ +FE RL+ E+ FR  + +  V ESD +I  + +   G    P   ++ ++ ++ E
Sbjct: 627 EYKISSFEQRLMNEIEFR--LERTPVDESDDEIQHD-EIPTGKCIAPIFDKRLKHFRVTE 683

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT--LRVRNTQKSDSGHYT 337
           G+   F  ++ G P P+V WFK+G+++   N+H  +      T  L + +T   D G+YT
Sbjct: 684 GSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYT 743

Query: 338 LLAENPNGCIVTSGYLAVES-PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
           ++A NP G I  SG+L V+S P  S +      +   ++ +E ++   + E+   P F++
Sbjct: 744 IMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE-PLQERFFRPHFLQ 802

Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              D    EG++ R DC+V+G P PE+TW +N + +  D +HK+LV E+G H+L+I  +T
Sbjct: 803 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 862

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
             D+G   C+A NK+G+ +F   L+V+ KE   AP  +E+     V EG PV L  R +G
Sbjct: 863 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIG 922

Query: 517 TPTPRITWQKDGVPI-IPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            P P   W+KD   I      + +H D  G + L I  AK SDA WY  +A+N AG  + 
Sbjct: 923 MPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSC 982

Query: 575 RARL 578
            ARL
Sbjct: 983 TARL 986



 Score =  111 bits (266), Expect = 8e-23
 Identities = 83/322 (25%), Positives = 133/322 (41%), Gaps = 22/322 (6%)

Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEE-D 4566
            G  + P F    ++  VT G  V    K+ G     VYW K+GK++     + K+  E D
Sbjct: 665  GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 724

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV-SLPA----------------TK 4609
            GT +L I      D G Y  +A N  G   C    +V SLP                  +
Sbjct: 725  GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 784

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKY 4668
            ++ K   +     P  ++   D +  EG+     CK+ G P P + W   G  ++  + +
Sbjct: 785  ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 844

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              + R    ++L I      D G YKC+A N  G+ + + +L V   +       L  L+
Sbjct: 845  KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQ 904

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN--AVLLIGNTYEE 4786
            +  V EG P + + ++     P   W ++   IP T +   +H+     A LLI    + 
Sbjct: 905  NCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKS 964

Query: 4787 DTGTFTCRATTAAGQVETSAKL 4808
            D G +T  A   AG V  +A+L
Sbjct: 965  DAGWYTLSAKNEAGIVSCTARL 986



 Score =  109 bits (263), Expect = 2e-22
 Identities = 106/418 (25%), Positives = 173/418 (41%), Gaps = 55/418 (13%)

Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI 4382
            +DN+ +T+    + + KK+T     P+  E  +   E  +  + + + E        R  
Sbjct: 598  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLE--------RTP 649

Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
                  EI+H         E P      PIF K+++  RV E     F  +  G P+P +
Sbjct: 650  VDESDDEIQHD--------EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKV 701

Query: 4443 KWYRENFPI-KNSPDFQIHTFSTKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             W+++   I K +   ++      +  L I     +D   +  +A N  G   CS +L+V
Sbjct: 702  YWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761

Query: 4501 EE-----------KRRQGRGGIVP------------PSFTLTAQNVNVTSGQLVRLDTKV 4537
            +            +  +GR  +              P F     ++    G+L RLD KV
Sbjct: 762  QSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV 821

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKIL-EEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            +G  P ++ WL NG+ V PD  +K+L  E G ++LLI     +D+G Y+C+A N  G+  
Sbjct: 822  SGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 881

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               E  V             K     P I+E L++  V EG  +   C+++G P P   W
Sbjct: 882  FSLELSV-----------VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYW 930

Query: 4657 YKGDKLIKPSK-YFQMSRTADEYT-LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             K ++ I  ++    M +    Y  L I  A   D G Y   A N AG V+  A+L +
Sbjct: 931  KKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 988



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 67/234 (28%), Positives = 98/234 (41%), Gaps = 13/234 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGY 1767
            AP+F   +K  RV E     F  +++ +  PK  V W ++G  I   N    M     G 
Sbjct: 669  APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPK--VYWFKDGKQISKRNEHCKMRREGDGT 726

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+++    +D G YT  A N  G    S  L VQS   L + S+  SA Q  +     
Sbjct: 727  CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---LPIRSRLTSAGQSHR---GR 780

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-V 1886
            SR Q R+   +          Q  G     EG+    +C++   P P +   W  NG+ V
Sbjct: 781  SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 838

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            L          + G  +L I  +   D+G Y C A N  GQ   S+ L+V +KE
Sbjct: 839  LPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 892



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 80/310 (25%), Positives = 130/310 (41%), Gaps = 21/310 (6%)

Query: 2941 PDLKIEWYFNGK-VLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P  K+ W+ +GK + ++    K+  +  G  +L +      D G YT  A N +G    S
Sbjct: 697  PVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCS 756

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
              +   S       T   +   G  ++Q  +    KEP Q+        P F     D+V
Sbjct: 757  GHLMVQSLPIRSRLTSAGQSHRGRSRVQERD----KEPLQE----RFFRPHFLQAPGDMV 808

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTT 3116
               EG++   +  +  +G     + W  NG+ +  +ASH++  V   G+  L I      
Sbjct: 809  -AHEGRLCRLDCKV--SGLPPPELTWLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQR 864

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D+GTY C ATNK GQ   S++L  V K   + P     +QN  G+ +G     EC V+ +
Sbjct: 865  DAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNC-GVPEGHPVRLECRVIGM 923

Query: 3177 DDPDMKIEWYHNGQPMRHS-TRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P     W  + + +  +  RI    D  G+  L I   +  D+G Y   A N+ G   
Sbjct: 924  PPP--VFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVS 981

Query: 3235 TRATINCYGK 3244
              A ++ Y +
Sbjct: 982  CTARLDIYAQ 991



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 76/276 (27%), Positives = 125/276 (45%), Gaps = 26/276 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH---RFKTTYDFGY 2034
            P F K +K+  VTEG PV     +  +  P  +V W+ +G+ + + +   + +   D G 
Sbjct: 670  PIFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGD-GT 726

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA---KSGLYLDTLDEQRLKKIQEL 2091
             +L I    ++D G Y   A N  G    +  + V +   +S L       +   ++QE 
Sbjct: 727  CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 786

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
            +K    +P++E     RP FL A   +    EG     +C+V  +  P LT  W  NGQ 
Sbjct: 787  DK----EPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQP 837

Query: 2152 IR--AGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
            +   A H+     + G  +L I      D+GTY C ATNK G+  N+ +L+++     + 
Sbjct: 838  VLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ--NSFSLELSVVAKEV- 893

Query: 2210 DTQHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRF 2244
              + P  LEK++     +GH  R+E     + PP F
Sbjct: 894  -KKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVF 928



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 75/311 (24%), Positives = 128/311 (41%), Gaps = 22/311 (7%)

Query: 3349 EENSGEYECVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKLQTLEDSMVR 3406
            ++N  E +      LG+  T ++++   +E  I   + +L   +E  LE+    E     
Sbjct: 598  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLERTPVDESDDEI 657

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            + D  +   K  AP+F   L +   + EG    F  ++     P  KV W+ +GK +   
Sbjct: 658  QHD-EIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKR 713

Query: 3467 S---RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            +   + R   D G   L I  T  +D G Y   A N  G    +  + VQ   ++ + S+
Sbjct: 714  NEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQ---SLPIRSR 769

Query: 3524 LPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIP 3583
            L    +    +    E          P  E    P F   P D++  E      +C++  
Sbjct: 770  LTSAGQSHRGRSRVQERDK------EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSG 823

Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEAT 3642
            +    +   W  NG+P+L  +  K  + + G   L I  + QRDAG Y C ATN+ G+ +
Sbjct: 824  LPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 881

Query: 3643 VSCKLQVKGRQ 3653
             S +L V  ++
Sbjct: 882  FSLELSVVAKE 892



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--- 4467
            P+FTK +Q     E +   FE    G P P ++WYRE   I++SPDF+I     +S+   
Sbjct: 160  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219

Query: 4468 -----LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
                 L+I +VF EDS  F   A N+ GT    A L V
Sbjct: 220  EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 12/152 (7%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--------MS 4672
            A P   + L++   +EGQ + F C++ G P P V+WY+   LI+ S  F+        M+
Sbjct: 158  AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 217

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN---LPALTPLRD 4729
               +  TL I+E F ED G + C A N  G V+  A+L V   +   N   L +     +
Sbjct: 218  EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 277

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            +   E QP+   ++  S  +P    L EG L+
Sbjct: 278  LAAIEPQPSPPHSEPPSVEQPPKPKL-EGVLV 308



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 72/256 (28%), Positives = 109/256 (42%), Gaps = 28/256 (10%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTLNDFG 3751
            P F   +K +  V EG PV F C++  VG P  ++ WF +G+  +  +   ++    D G
Sbjct: 670  PIFDKRLK-HFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGD-G 725

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
              +L I+   + D G YT  A N  G      +I+CS    +V    +   ++       
Sbjct: 726  TCSLHIESTTSDDDGNYTIMAANPQG------RISCSGHL-MVQSLPIRSRLTSAGQSHR 778

Query: 3812 ERGRISDAPKEEPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
             R R+ +  KE P+      P F+         E    R +C+V     P+L   W  NG
Sbjct: 779  GRSRVQERDKE-PLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNG 835

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS-----CKK 3923
            + +LP       V + G  SL I  +   D+G Y C A N  G++     +S      KK
Sbjct: 836  QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK 895

Query: 3924 LPDII--LQN-QVPRG 3936
             P I+  LQN  VP G
Sbjct: 896  APVILEKLQNCGVPEG 911



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 70/266 (26%), Positives = 119/266 (44%), Gaps = 30/266 (11%)

Query: 1168 QIEEISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            Q +EI   K   P+F + L +   V+EG  +   C++  +G P  +V WF +G+ ++  +
Sbjct: 658  QHDEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRN 714

Query: 1225 ---RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE---RSDIVTD 1278
               + +   D G  +L I   TS D G YT+ A N  G    S  + V     RS + + 
Sbjct: 715  EHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSA 773

Query: 1279 TQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVG 1338
             Q+ +   ++Q  +    + +  R        P F +A  ++   EG    L+C++   G
Sbjct: 774  GQSHRGRSRVQERDKEPLQERFFR--------PHFLQAPGDMVAHEGRLCRLDCKVS--G 823

Query: 1339 DQTMRVEWFCNGKPI--KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                 + W  NG+P+     H+     E    +L +  +   D+G Y C ATN+ G+   
Sbjct: 824  LPPPELTWLLNGQPVLPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSF 882

Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQ 1422
            S  L V+AK+      + P  LEK+Q
Sbjct: 883  SLELSVVAKE----VKKAPVILEKLQ 904



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 63/230 (27%), Positives = 95/230 (41%), Gaps = 15/230 (6%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI-KTGHRFRPAYEFDYV 1368
            AP F + L +    EG+ V   C++  VG    +V WF +GK I K     +   E D  
Sbjct: 669  APIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 726

Query: 1369 -ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
             +L + S   +D G YT  A N  G    S  L V   + L + S+  S  +  +     
Sbjct: 727  CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQSHRGRSRV 783

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
                K  + +     +P F+  P  +    EG+    +CK+  +    L   W  NGQPV
Sbjct: 784  QERDKEPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 838

Query: 1488 T--IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
                 H+   + + G  +L I  L   D+G Y C A N  G +  S  L+
Sbjct: 839  LPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELS 887



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 61/237 (25%), Positives = 100/237 (42%), Gaps = 13/237 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694
           P F   LK     EG  + F  +I  VG P  K+ W K+G+ I   +    + R G    
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTC 727

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
           SL + S    D G YT  A +  G       L V       R +   ++ +   ++++  
Sbjct: 728 SLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERD 787

Query: 755 KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT 814
           K    E ++E+   RP F++   D+    EGR    + +++ +  P +   W  +G+P+ 
Sbjct: 788 K----EPLQERFF-RPHFLQAPGDM-VAHEGRLCRLDCKVSGLPPPELT--WLLNGQPVL 839

Query: 815 A-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
             +S    +   G  SL I  L   DAG+Y   A NK G+   +  + V A+    A
Sbjct: 840 PDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKA 896



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 7/105 (6%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F K+ Q+   +EG++  F+CRV G P P+V W+     I D  + +IL  +  + A 
Sbjct: 159 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218

Query: 450 ------LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
                 L+I  V   DSG  TC A NK G  +   +L+V   E +
Sbjct: 219 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 62/244 (25%), Positives = 97/244 (39%), Gaps = 13/244 (5%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            LE+    ES +  +  EIP       P+F + L++   + EG    F C++  VG P  K
Sbjct: 645  LERTPVDESDDEIQHDEIPTGKCIA-PIFDKRLKHF-RVTEGSPVTFTCKI--VGIPVPK 700

Query: 2410 VEWFRNEKLIEDSSRITKTH--DFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            V WF++ K I   +   K      G  S+ I     +D+G Y   A+N  G         
Sbjct: 701  VYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 760

Query: 2468 XXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAH 2527
                  + + ++     +  +   +  ER  E     F +P F Q   G     EG+   
Sbjct: 761  VQS---LPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQA-PGDMVAHEGRLCR 816

Query: 2528 YEARVVPVGDPSLRFEWYINGVE-LKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAI 2586
             + +V  +  P L   W +NG   L   S      + G  +L I+ +   DAG Y C A 
Sbjct: 817  LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIAT 874

Query: 2587 NRAG 2590
            N+ G
Sbjct: 875  NKTG 878



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 60/226 (26%), Positives = 102/226 (45%), Gaps = 19/226 (8%)

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS---RVKTINDFGFVILEIGGVYQR 3625
            ++E S   F C+++ +     +V WF +GK +   +   +++   D G   L I      
Sbjct: 681  VTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSD 737

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEI 3685
            D G YT  A N  G  + S  L V   Q + +  +L S  +S      +    + +R++ 
Sbjct: 738  DDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQS-----HRGRSRVQERDKE 789

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP-FATGSRV 3744
             ++ E+   P F ++   ++   EG     DC+V   G P   + W  NG+P     S  
Sbjct: 790  PLQ-ERFFRPHF-LQAPGDMVAHEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHK 845

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              + + G  +L ID +  RDAG Y C ATNK G  + + +++  AK
Sbjct: 846  MLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 891



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 60/242 (24%), Positives = 103/242 (42%), Gaps = 17/242 (7%)

Query: 1571 DEVTTQ---APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            DE+ T    API    LK+  + EG    F  +++ +     KV W+ + K +   +   
Sbjct: 660  DEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIP--VPKVYWFKDGKQISKRNEHC 717

Query: 1628 ETNNFG--FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
            +    G    +L I S   +D G YT  A N  G    SG  +V   +S+ + S+   A 
Sbjct: 718  KMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAG 774

Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
                      +  +   Q+      P F     D+   E +    + ++  +  P+L   
Sbjct: 775  QSHRGRSRVQERDKEPLQERFF--RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL--T 830

Query: 1746 WLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            WL NG P+  +AS+++  + + G  +L +  +   D+GTY C A N+ G+   S  L V 
Sbjct: 831  WLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVV 889

Query: 1804 SK 1805
            +K
Sbjct: 890  AK 891



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 50/172 (29%), Positives = 76/172 (44%), Gaps = 15/172 (8%)

Query: 1789 NELGEAVTSSTLFVQSKASLQ-LESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFI 1847
            NE+    T+S +   +    Q L +Q   A   IQQ +  + Y +  D +  +  AP F 
Sbjct: 107  NEVSSPPTTSAVIPPAVPQAQHLVAQPRVAT--IQQCQSPTNYLQGLDGKPII-AAPVFT 163

Query: 1848 TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT--------SNDF 1899
              L      SEGQ   +ECR++  P P  +VEWY  G +++    +R         +   
Sbjct: 164  KMLQN-LSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPE 220

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
                L I  V+ EDSG +TC A N  G   S  +L+V+  E +  +    SA
Sbjct: 221  EICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 272



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 8/93 (8%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--------L 4778
            L+++   EGQ   F+ ++     P ++W REG LI ++PDF+++ +   ++        L
Sbjct: 166  LQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTL 225

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +I   + ED+G FTC A+   G V + A+L V+
Sbjct: 226  VIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVR 258



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 15/222 (6%)

Query: 3985 LVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY--DFGYVAMNFGWVYPED 4042
            + E     F C++  VG P  KV WF +GK +  +N    +     G  +++      +D
Sbjct: 681  VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDD 738

Query: 4043 SGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             G Y   A N  G       +     P       +   + S  +     +  Q   ++ +
Sbjct: 739  DGNYTIMAANPQGRISCSGHLMVQSLP-------IRSRLTSAGQSHRGRSRVQERDKEPL 791

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY- 4161
            +E   R  P F+  P  +   EG   R  C+V+G P P + WLLNG  ++  + +K+   
Sbjct: 792  QERFFR--PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 849

Query: 4162 -DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
              G++   I    Q D G  + I             L V+ +
Sbjct: 850  ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 891



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 68/275 (24%), Positives = 113/275 (41%), Gaps = 26/275 (9%)

Query: 751  EDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG 810
            E   + QH E I       P F + L+    + EG    F  ++  +  P  +V W+KDG
Sbjct: 652  ESDDEIQHDE-IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGI--PVPKVYWFKDG 707

Query: 811  RPITASSRITSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
            + I+  +    +   G    SL+I    ++D G+YT+ A N  G    +  + V +    
Sbjct: 708  KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---- 763

Query: 869  TADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
                 +P + R +                    + E   +P F     D ++  EG    
Sbjct: 764  -----LPIRSR-LTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVA-HEGRLCR 816

Query: 929  FEARLEPIGDSTLRVEWLKDGRPV--EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
             + ++  +    L   WL +G+PV  +AS ++      G  +L I  +T  DAG Y C A
Sbjct: 817  LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVR-ETGVHSLLIDPLTQRDAGTYKCIA 873

Query: 987  YNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             N  GQ + S  L++V K+      + P  LEK+Q
Sbjct: 874  TNKTGQNSFSLELSVVAKE----VKKAPVILEKLQ 904



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 59/237 (24%), Positives = 95/237 (40%), Gaps = 19/237 (8%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVS 2832
            +F   L +    EG  + F C +     P  K+ WF + K +     +           S
Sbjct: 671  IFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 728

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE 2892
            L I  T  +D G YT  A N +G  + SG L            Q    ++ L +  Q+  
Sbjct: 729  LHIESTTSDDDGNYTIMAANPQGRISCSGHLM----------VQSLPIRSRLTSAGQSHR 778

Query: 2893 ARLAKGRRPSVPDTE-YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNG 2951
             R     R   P  E + +P + +    +    EG++  L+ +V     P+L   W  NG
Sbjct: 779  GRSRVQERDKEPLQERFFRPHF-LQAPGDMVAHEGRLCRLDCKVSGLPPPEL--TWLLNG 835

Query: 2952 K-VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
            + VL   S   L  + G  +L +  + +RD+G Y C A NK G+   S  +   +K+
Sbjct: 836  QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 892



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 8/103 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
           K  + AP F +    L+  EG+ VV   R  G P+P++ W ++G  I  +P+ RI     
Sbjct: 154 KPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKP 213

Query: 545 AS--------TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            S        TL I    A D+  + CTA N  G+ ++ A+L+
Sbjct: 214 RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLH 256



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 10/110 (9%)

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR------ 1360
            ++ AP F++ L N+   EG  V  ECR++  G  + +VEW+  G  I+    FR      
Sbjct: 156  IIAAPVFTKMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKP 213

Query: 1361 --PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
               A   +   L +  V+ EDSG +TC A+N+ G   +   L V   +DL
Sbjct: 214  RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 37/91 (40%), Positives = 49/91 (53%), Gaps = 11/91 (12%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKTHDFGY 2433
            PVFT+ LQN+ +  EGQ   F+CR+   G P+ KVEW+R   LIEDS   RI +      
Sbjct: 160  PVFTKMLQNL-SASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 2434 V------SMTISHVRDEDEGVYMCRASNLLG 2458
                   ++ I+ V  ED G + C ASN  G
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 23/238 (9%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM---RHSTRIKTVSDFG 3205
            P F   +++   + +G    F C +V +  P  K+ W+ +G+ +       +++   D G
Sbjct: 670  PIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCKMRREGD-G 725

Query: 3206 FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDS-LAKIRELE 3264
               L I  T + D G Y   A N  G       I+C   G + ++SL   S L    +  
Sbjct: 726  TCSLHIESTTSDDDGNYTIMAANPQGR------ISC--SGHLMVQSLPIRSRLTSAGQSH 777

Query: 3265 SLQGAQQQTPSTPSAEP---PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321
              +   Q+    P  E    P F+    D+    EG+    + ++  +  P+L   W  N
Sbjct: 778  RGRSRVQERDKEPLQERFFRPHFLQAPGDMVAH-EGRLCRLDCKVSGLPPPELT--WLLN 834

Query: 3322 GKK-LPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            G+  LP         + G+  L I    + ++G Y+C+ATNK G++S    L   +KE
Sbjct: 835  GQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 892



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 57/214 (26%), Positives = 98/214 (45%), Gaps = 25/214 (11%)

Query: 1077 VEWYFNGKQITSAN---RIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            V W+ +GKQI+  N   +++   D G  +L I S  ++D G YT++A N  G    S  +
Sbjct: 701  VYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 759

Query: 1134 TVET---RSSIDTS-SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPV 1189
             V++   RS + ++   HRG   ++R  E  K  EP+ +       +P F+Q        
Sbjct: 760  MVQSLPIRSRLTSAGQSHRG---RSRVQERDK--EPLQE----RFFRPHFLQ-APGDMVA 809

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGFVALDIIHATSADTG 1248
             EG+   L+C++   G P   + W  NG+ V   +  K    + G  +L I   T  D G
Sbjct: 810  HEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAG 867

Query: 1249 EYTVRAVNHLG----SAHTSAIVRVIERSDIVTD 1278
             Y   A N  G    S   S + + ++++ ++ +
Sbjct: 868  TYKCIATNKTGQNSFSLELSVVAKEVKKAPVILE 901



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 34/221 (15%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT--THNHTTL 323
           P   Q P +    EG   +   ++SG P P +TW  NGQ ++    H+++   T  H+ L
Sbjct: 798 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 857

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
               TQ+ D+G Y         CI T+                     T       E  +
Sbjct: 858 IDPLTQR-DAGTYK--------CIATNK--------------------TGQNSFSLELSV 888

Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
              E   AP  ++  Q+  V EG   R +CRV G P P V ++  D +       +I ++
Sbjct: 889 VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMP-PPVFYWKKDNETIPCTRERISMH 947

Query: 444 E--SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           +  +G   L+I     SD+G  T  A+N++G  +   RL++
Sbjct: 948 QDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 988



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 33/112 (29%), Positives = 49/112 (43%)

Query: 50  TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
           T V+ S D         G+   PIF++  K+ R  +G    F  K+ G P P V W +  
Sbjct: 648 TPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDG 707

Query: 110 APLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             + + N++     E  G  SL I+     D+G YT  A N  G   CS ++
Sbjct: 708 KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 759



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 53/233 (22%), Positives = 93/233 (39%), Gaps = 30/233 (12%)

Query: 524 WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXX 583
           W  +G  +  +P++ I   G   +L I  A   D   Y C A N+ G+ +T A +Y    
Sbjct: 27  WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 584 XXXXXX-----QKRLHLPRPTKVXXXXXXXXXXXXYLRHVER--ARP------------- 623
                      ++   + +P +V             +   +   A+P             
Sbjct: 87  SSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTN 146

Query: 624 YIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS 683
           Y+   +   +   P F   L++++A EG  + FE R++  G P+ K+EW + G  IE S 
Sbjct: 147 YLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSP 204

Query: 684 RFTSIFR--------FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            F  + +            +L +  +  +DSG +TC A +  G   + A LHV
Sbjct: 205 DFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 12/145 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG--- 3751
            P FT ++  N+   EG  V F+CRV+  G P+ +++W+  G           L       
Sbjct: 160  PVFT-KMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 3752 -----FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
                    L I  ++A D+G +TC A+NK+G+ ++ A++      D+     L    S  
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTT 276

Query: 3807 KIKELERGRISDAPKEEPIVSTPPK 3831
             +  +E  + S    E P V  PPK
Sbjct: 277  NLAAIE-PQPSPPHSEPPSVEQPPK 300



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 104/250 (41%), Gaps = 22/250 (8%)

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276
            LE+    E+       E+   K   P F   L+    V EG    F C++  +  P  ++
Sbjct: 645  LERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KV 701

Query: 2277 EFYHNGKALQSAARFHITF---DFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAIS 2331
             ++ +GK + S    H        G  SL I+    +D G Y++ A N  G   C+  + 
Sbjct: 702  YWFKDGKQI-SKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 760

Query: 2332 M-TVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390
            + ++  +  + S  Q   G  +++E +  EP +           RP F Q   ++    E
Sbjct: 761  VQSLPIRSRLTSAGQSHRGRSRVQERDK-EPLQERFF-------RPHFLQAPGDMV-AHE 811

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            G+    DC++   G P  ++ W  N + ++ D+S      + G  S+ I  +   D G Y
Sbjct: 812  GRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 869

Query: 2450 MCRASNLLGE 2459
             C A+N  G+
Sbjct: 870  KCIATNKTGQ 879



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 57/231 (24%), Positives = 89/231 (38%), Gaps = 13/231 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG---AR 2690
            + TG   APIF   LK + ++ EG  V    ++     P  K+ WFK+G  ++      +
Sbjct: 662  IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCK 718

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            ++   D G  +L I S  +DD G YT  A N  G    +  + ++     +   L     
Sbjct: 719  MRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSAGQ 775

Query: 2751 DRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWF 2810
               G                     F+    ++V  EG     +C V  S  P  ++ W 
Sbjct: 776  SHRGR-SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV--SGLPPPELTWL 832

Query: 2811 FNNKP-LPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
             N +P LP  +      +    SL I    + D+G Y C ATN  G  + S
Sbjct: 833  LNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFS 883



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 14/151 (9%)

Query: 1678 ESQHEGALPR---LNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARL 1734
            ++QH  A PR   + Q +  + Y +     + I  APVFT  ++++  +E Q   FE R+
Sbjct: 125  QAQHLVAQPRVATIQQCQSPTNYLQ-GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRV 183

Query: 1735 IPVGDPKLRVEWLRNGVPIEAS-------NRLTTMHDFGYV-ALNMKYVNPEDSGTYTCR 1786
               G P  +VEW R G  IE S        +  +M +   +  L +  V  EDSG +TC 
Sbjct: 184  --KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCT 241

Query: 1787 AINELGEAVTSSTLFVQSKASLQLESQHESA 1817
            A N+ G   + + L V+    L       SA
Sbjct: 242  ASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 272



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIR----- 4559
            G+  I  P FT   QN++ + GQLV  + +V G     V W + G  ++  PD R     
Sbjct: 153  GKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKK 212

Query: 4560 -NKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
               + E +   TL+I E + +DSG + C A N  G
Sbjct: 213  PRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 43/149 (28%), Positives = 62/149 (41%), Gaps = 13/149 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APVFT  L N+ +  EG+   FE R+     P  KVEWY  G  ++    FR        
Sbjct: 159  APVFTKMLQNL-SASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRS 215

Query: 3479 ILE--------ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530
            + E        I+  + EDSG + C A N YG   + A + V+G  ++     L      
Sbjct: 216  MAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANST 275

Query: 3531 TIDKIAALEGYSGTVDTLTPEAESGNPPE 3559
            T   +AA+E       +  P  E    P+
Sbjct: 276  T--NLAAIEPQPSPPHSEPPSVEQPPKPK 302



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 62/260 (23%), Positives = 97/260 (37%), Gaps = 43/260 (16%)

Query: 3456 WYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            WY  GK L+               L I+  + ED+G Y C A N YG   T+A + ++G 
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 3516 RNIILESQLPKGMEGTIDK---IAALEGYSGTVDTLTPEAE------------------- 3553
             +   E    K     I K   +++    S  +    P+A+                   
Sbjct: 87   SSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTN 146

Query: 3554 -----SGNP----PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG-----KP 3599
                  G P    P FT    +L  SE     FECR+      S +VEW+  G      P
Sbjct: 147  YLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSP 204

Query: 3600 ---LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGII 3656
               +L               L I  V+  D+G +TC A+N++G  +   +L V+G + + 
Sbjct: 205  DFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS 264

Query: 3657 LEPQLPSHFKSGTESIQKLE 3676
                L  H  + T ++  +E
Sbjct: 265  NNGSL--HSANSTTNLAAIE 282



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 11/97 (11%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            +PI++ P  F   +++ +  E + V FECRV+    PK  +EWYR G L+     +R + 
Sbjct: 154  KPIIAAPV-FTKMLQNLSASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQ 210

Query: 3883 DMG--------FVSLDILYVYAEDSGEYICRAVNDFG 3911
                         +L I  V+AEDSG + C A N +G
Sbjct: 211  KKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 18/143 (12%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG--- 3205
            P FT  +QN+    +GQ   FEC V     P  K+EWY  G  +  S   + +       
Sbjct: 160  PVFTKMLQNLSA-SEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 3206 -----FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD-SLAK 3259
                    L IA     DSG + C A NKYG   + A ++  G      E L  + SL  
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGN-----EDLSNNGSLHS 271

Query: 3260 IRELESLQGAQQQTPSTPSAEPP 3282
                 +L   + Q PS P +EPP
Sbjct: 272  ANSTTNLAAIEPQ-PSPPHSEPP 293



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 21/142 (14%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-------- 2160
            PVF   L +L +  EG    FECRV+    P   ++W+  G  I     +R         
Sbjct: 160  PVFTKMLQNL-SASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKI 2220
                    L I   +AEDSG + C A+NK G   +   L V G+ ++       NG    
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL-----SNNG---- 267

Query: 2221 RQLEAQGHSTRIEVEEPKISPP 2242
              L +   +T +   EP+ SPP
Sbjct: 268  -SLHSANSTTNLAAIEPQPSPP 288



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 20/58 (34%), Positives = 32/58 (55%)

Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            W  EG  +  +PD  ++  GN   L I   +EEDTG ++C A+   G   TSA++ ++
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 84



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 10/99 (10%)

Query: 64  GRPGEP--SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE------- 114
           G  G+P  + P+F ++ +N   ++G    FE +++G P+P V W R +  L+E       
Sbjct: 150 GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYR-EGTLIEDSPDFRI 208

Query: 115 CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
             K      E     +L+I ++   D G +TCTA N+YG
Sbjct: 209 LQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 10/105 (9%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--------STH 2826
            VF   L N+   EG  + FEC V+ +  P  K+EW+     +     ++           
Sbjct: 161  VFTKMLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAE 218

Query: 2827 DFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
                 +L I   + EDSG +TC A+N  G+ ++   L   G++++
Sbjct: 219  PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 58/224 (25%), Positives = 89/224 (39%), Gaps = 43/224 (19%)

Query: 2947 WYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY---C 3003
            WY  GK LE      +       +L + + +E D+G Y+C A N  G   TS+ +Y    
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 3004 TSKDN-------LIERTQHPKGTE-----------GLEKIQNLEDSLRKEPGQQPDDDT- 3044
            +S D+        + R Q P                + + Q+L    R    QQ    T 
Sbjct: 87   SSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTN 146

Query: 3045 ------GRP----PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS 3094
                  G+P    P FT + +++   SEGQ+  +E  +   G  S  +EW+  G  IE S
Sbjct: 147  YLQGLDGKPIIAAPVFTKMLQNL-SASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDS 203

Query: 3095 HRIRTVY--------AFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
               R +            +  L I      DSG ++C A+NK+G
Sbjct: 204  PDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+V +EG+  +   +++    P + WL  G  ++P+     ++ E     LLI    + D
Sbjct: 806  DMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRD 865

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             GT+ C AT   GQ   S +L V +K
Sbjct: 866  AGTYKCIATNKTGQNSFSLELSVVAK 891



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 63/232 (27%), Positives = 90/232 (38%), Gaps = 17/232 (7%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH-- 1491
            D I     I P F  R K    V EG  V F CK+  +     KV WFK+G+ ++  +  
Sbjct: 660  DEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEH 716

Query: 1492 -RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             + R   D G  +L I    ++D G YT  A N  G    S  L  +S    +RS    A
Sbjct: 717  CKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSA 773

Query: 1551 GLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL 1609
            G    Q    RS+    D    +     P    +  ++   EG+    + ++  +    L
Sbjct: 774  G----QSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL 829

Query: 1610 KVEWYHNNKP-LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
               W  N +P L   S        G  +L I      D+GTY C A N  G+
Sbjct: 830  --TWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ 879



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL--------TSDFGFVTLDLVDV 2976
            EGQ++  E +V  K  P  K+EWY  G ++E    F++               TL + +V
Sbjct: 173  EGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 230

Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL 3009
            +  DSG +TC A NK G   + + ++    ++L
Sbjct: 231  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGD 128
           +P I E++ +N    +G   + E ++ G P PV  W +K    + C +  +  + + TG 
Sbjct: 896 APVILEKL-QNCGVPEGHPVRLECRVIGMPPPVFYW-KKDNETIPCTRERISMHQDTTGY 953

Query: 129 VSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
             LLI+     D G YT +A+N+ G   C+
Sbjct: 954 ACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 983



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 11/132 (8%)

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
            +A I++ +S     Q     P    P F   +Q+++   EGQ   FE R+     P  KV
Sbjct: 135  VATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSAS-EGQLVVFECRVKGAPSP--KV 191

Query: 3317 EWFYNGKKLPHGHRYRTFHDFG--------IVILDILYCYEENSGEYECVATNKLGRDST 3368
            EW+  G  +     +R              I  L I   + E+SG + C A+NK G  S+
Sbjct: 192  EWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSS 251

Query: 3369 KANLKCTSKENL 3380
             A L     E+L
Sbjct: 252  IAQLHVRGNEDL 263



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 10/93 (10%)

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG--------YVALDIIDL 1509
            EGQ V FEC+++       KVEW++ G  +     FR +               L I ++
Sbjct: 173  EGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 230

Query: 1510 IAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
             AEDSG +TC A N  GT     +L  R   D+
Sbjct: 231  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF-ATGS 3742
            E+++  ++       +E   N  VPEG PV  +CRV  +G P     W  +      T  
Sbjct: 885  ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV--IGMPPPVFYWKKDNETIPCTRE 942

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            R+    D  G+  L I      DAG YT  A N+ G  + TA++   A+
Sbjct: 943  RISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 991



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/106 (30%), Positives = 43/106 (40%), Gaps = 6/106 (5%)

Query: 3185 WYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244
            WY  G+ + +S  I  V       L IA     D+G Y C A N YG D T A I   G 
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG- 85

Query: 3245 GGVYLESLQPDSLAKIRELESLQGAQQ-QTPSTPSAEPPKFITQIQ 3289
                + S   +      E+  +Q   +  +P T SA  P  + Q Q
Sbjct: 86   ----VSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQ 127



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 1/86 (1%)

Query: 2013 WYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            WYC G+ ++              +L I  A+ EDTG Y C A+N  G   T++ + ++  
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 2073 SGLYLD-TLDEQRLKKIQELEKYERP 2097
            S    +   +++ + +IQ+  +   P
Sbjct: 87   SSSDSEGDPNKEEMNRIQKPNEVSSP 112



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 11/129 (8%)

Query: 1955 IQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWY 2014
            IQ  +  + Y + + D   ++  P F K ++N   +EG  V  E  +     P+ +VEWY
Sbjct: 138  IQQCQSPTNYLQGL-DGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGA--PSPKVEWY 194

Query: 2015 CNGRPVQQGHRFKTTYDFG--------YVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
              G  ++    F+                 L I   +AED+G + C A+N  G   + + 
Sbjct: 195  REGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQ 254

Query: 2067 VKVDAKSGL 2075
            + V     L
Sbjct: 255  LHVRGNEDL 263



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 8/88 (9%)

Query: 4547 WLKNGKKVQ--PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC--- 4601
            W   GK+++  PDI   I++    ++L I EA+ +D+G+Y C A N  G     AE    
Sbjct: 27   WYCEGKELENSPDIH--IVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 84

Query: 4602 -VVSLPATKDKPKPQTKAANAPPEIIEP 4628
             V S  +  D  K +      P E+  P
Sbjct: 85   GVSSSDSEGDPNKEEMNRIQKPNEVSSP 112



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/58 (34%), Positives = 28/58 (48%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            WY E   ++NSPD  I        L I + F ED+  ++  A N  GT   SA + +E
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 84



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           + ++  + P  +  LQ+ G + EG     E ++  +  P     W KD   I  +    S
Sbjct: 889 VAKEVKKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERIS 945

Query: 822 IFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           +     GY  L I   +  DAG YT+ A N+ G    TA + + A+
Sbjct: 946 MHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 991



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 11/91 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-------- 2559
            P+FT++L   S   EGQ   +E RV   G PS + EWY  G  ++    FR         
Sbjct: 160  PVFTKMLQNLSAS-EGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 2560 THDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   TL I  V A D+G + C A N+ G
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 247



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           +G   + + K+ G P P ++W     P++    + M   E TG  SLLI  +   D G Y
Sbjct: 811 EGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRE-TGVHSLLIDPLTQRDAGTY 869

Query: 145 TCTARNQYGE 154
            C A N+ G+
Sbjct: 870 KCIATNKTGQ 879



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 9/121 (7%)

Query: 2278 FYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
            +Y  GK L+++   HI       SL I     ED G YS  A N  G  T + S  +  +
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYG--TDSTSAEIYIE 84

Query: 2338 GSIISESQRPEGLEKIRELE-----SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQ 2392
            G   S+S+     E++  ++     S+ P     IP  V + + +  QP   +  IQ+ Q
Sbjct: 85   GVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQP--RVATIQQCQ 142

Query: 2393 T 2393
            +
Sbjct: 143  S 143



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 19/65 (29%), Positives = 34/65 (52%)

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            WY   K ++ S    + +  + ++L I+EAF ED G Y C A N  G  + +A++ +   
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 4716 DQADN 4720
              +D+
Sbjct: 87   SSSDS 91



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3318 WFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            W+  GK+L +           +  L I   +EE++G Y C A+N  G DST A +
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 81



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--------TE 1628
            AP+ T  L+N+   EGQ   FE R+      + KVEWY     ++    F        + 
Sbjct: 159  APVFTKMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
                    L I     EDSG +TC A N  G    S IA +H
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG--TVSSIAQLH 256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 4/117 (3%)

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
            W+  GK L +      +      ++     + ED+G Y C A+N+YG D T A I   G 
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 4069 PGIVYDSQLPKHMKSIEKIRE-MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEE 4124
                 DS+   + + + +I++  E S   T   V+  +  +   + V+ P   T+++
Sbjct: 87   SS--SDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHL-VAQPRVATIQQ 140



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            PVF  +   ++  EG+   F CRV G P P+V W   G  I +   +++
Sbjct: 160  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRI 208



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 21/55 (38%), Positives = 25/55 (45%)

Query: 3865 WYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            WY  GK L +      V      SL I   + ED+G Y C A N +G D T A I
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 81



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 4/88 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-- 1764
            + +APV    +++  V E      E R+I  G P     W ++   I  +    +MH   
Sbjct: 893  VKKAPVILEKLQNCGVPEGHPVRLECRVI--GMPPPVFYWKKDNETIPCTRERISMHQDT 950

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELG 1792
             GY  L ++     D+G YT  A NE G
Sbjct: 951  TGYACLLIQPAKKSDAGWYTLSAKNEAG 978



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/127 (22%), Positives = 53/127 (41%), Gaps = 5/127 (3%)

Query: 2809 WFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGD 2868
            W+   K L +          +  SL I   +EED+G Y+C A+N  G+ +TS  +   G 
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 2869 KNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWII--PIAAEHQLVEG 2926
             +   D++    K  +  +++  E          +P    P+ + ++  P  A  Q  + 
Sbjct: 87   SS--SDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPA-VPQAQHLVAQPRVATIQQCQS 143

Query: 2927 QVLHLEG 2933
               +L+G
Sbjct: 144  PTNYLQG 150



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/101 (22%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ--------RLINSNKHEI 314
           ++ P   +  +N    EG    F+ ++ G P P+V W++ G         R++      +
Sbjct: 157 IAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
                  TL +      DSG +T  A N  G + +   L V
Sbjct: 217 AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/65 (32%), Positives = 31/65 (47%)

Query: 1079 WYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            WY  GK++ ++  I         +L IA    ED+G Y+  A N  G    SA + +E  
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 1139 SSIDT 1143
            SS D+
Sbjct: 87   SSSDS 91



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT-VGSRFKTYYDF 1232
            K  PV ++ L N   V EG  + LECR+  M  P     W  +  ++     R   + D 
Sbjct: 894  KKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERISMHQDT 950

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             G+  L I  A  +D G YT+ A N  G    +A
Sbjct: 951  TGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTA 984



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 15/55 (27%), Positives = 28/55 (50%)

Query: 3731 WFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            W+  G+       +H +      +L I   +  D G Y+C A+N +G+ +T+A+I
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 81



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 37/164 (22%), Positives = 59/164 (35%), Gaps = 11/164 (6%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY---KLTYDGMYHF 4167
            P+F        V EG    F C++ G P P+V W  +G  I   + +   +   DG    
Sbjct: 670  PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRT 4227
             I  T   D G   ++             L V  +    R  L +A +     +   +R 
Sbjct: 730  HIESTTSDDDGNYTIMAANPQGRISCSGHLMV--QSLPIRSRLTSAGQSHRGRSRVQERD 787

Query: 4228 ETELEKTFEERQVLQRQG-VIDH-----RPELKPKVIKEPETEW 4265
            +  L++ F     LQ  G ++ H     R + K   +  PE  W
Sbjct: 788  KEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTW 831



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/101 (23%), Positives = 42/101 (41%)

Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           W+  G+ L NS    I+   N  +L +    + D+G Y+  A N  G   TS  + +E  
Sbjct: 27  WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGV 86

Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ 399
           + S  +   ++   +  Q+  E     +  A+ P  V   Q
Sbjct: 87  SSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQ 127



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/55 (34%), Positives = 27/55 (49%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            W+  GK +E S  I  V A  +  L I      D+G YSC A+N +G    S ++
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 81



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG-----KP---LLHKNRFTP 4024
            P F   +Q+  S  E +   FEC++   G P+ KVEW+  G      P   +L K   + 
Sbjct: 160  PVFTKMLQN-LSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQL 4077
                    +    V+ EDSG + C A+N YG   + A +   G   +  +  L
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSL 269



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/57 (26%), Positives = 27/57 (47%)

Query: 1346 WFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            W+C GK ++           +  +L +   + ED+G Y+C A+N  G   TS  + +
Sbjct: 27   WYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 83



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY------ 1230
            PVF + L N    SEG+ +  ECR++  G P+ +VEW+  G  +     F+         
Sbjct: 160  PVFTKMLQNLS-ASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 216

Query: 1231 --DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
                    L I    + D+G +T  A N  G+  + A + V    D+
Sbjct: 217  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 263


>AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein.
          Length = 1320

 Score =  226 bits (553), Expect = 1e-57
 Identities = 124/364 (34%), Positives = 200/364 (54%), Gaps = 9/364 (2%)

Query: 220  DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQE 279
            ++K+ +FE RL+ E+ FR  + +  V ESD +I  + +   G    P   ++ ++ ++ E
Sbjct: 902  EYKISSFEQRLMNEIEFR--LERTPVDESDDEIQHD-EIPTGKCIAPIFDKRLKHFRVTE 958

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT--LRVRNTQKSDSGHYT 337
            G+   F  ++ G P P+V WFK+G+++   N+H  +      T  L + +T   D G+YT
Sbjct: 959  GSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYT 1018

Query: 338  LLAENPNGCIVTSGYLAVES-PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            ++A NP G I  SG+L V+S P  S +      +   ++ +E ++   + E+   P F++
Sbjct: 1019 IMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE-PLQERFFRPHFLQ 1077

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
               D    EG++ R DC+V+G P PE+TW +N + +  D +HK+LV E+G H+L+I  +T
Sbjct: 1078 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 1137

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
              D+G   C+A NK+G+ +F   L+V+ KE   AP  +E+     V EG PV L  R +G
Sbjct: 1138 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIG 1197

Query: 517  TPTPRITWQKDGVPI-IPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
             P P   W+KD   I      + +H D  G + L I  AK SDA WY  +A+N AG  + 
Sbjct: 1198 MPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSC 1257

Query: 575  RARL 578
             ARL
Sbjct: 1258 TARL 1261



 Score =  111 bits (266), Expect = 8e-23
 Identities = 83/322 (25%), Positives = 133/322 (41%), Gaps = 22/322 (6%)

Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEE-D 4566
            G  + P F    ++  VT G  V    K+ G     VYW K+GK++     + K+  E D
Sbjct: 940  GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 999

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV-SLPA----------------TK 4609
            GT +L I      D G Y  +A N  G   C    +V SLP                  +
Sbjct: 1000 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1059

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKY 4668
            ++ K   +     P  ++   D +  EG+     CK+ G P P + W   G  ++  + +
Sbjct: 1060 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 1119

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              + R    ++L I      D G YKC+A N  G+ + + +L V   +       L  L+
Sbjct: 1120 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQ 1179

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN--AVLLIGNTYEE 4786
            +  V EG P + + ++     P   W ++   IP T +   +H+     A LLI    + 
Sbjct: 1180 NCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKS 1239

Query: 4787 DTGTFTCRATTAAGQVETSAKL 4808
            D G +T  A   AG V  +A+L
Sbjct: 1240 DAGWYTLSAKNEAGIVSCTARL 1261



 Score =  109 bits (263), Expect = 2e-22
 Identities = 106/418 (25%), Positives = 173/418 (41%), Gaps = 55/418 (13%)

Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI 4382
            +DN+ +T+    + + KK+T     P+  E  +   E  +  + + + E        R  
Sbjct: 873  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLE--------RTP 924

Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
                  EI+H         E P      PIF K+++  RV E     F  +  G P+P +
Sbjct: 925  VDESDDEIQHD--------EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKV 976

Query: 4443 KWYRENFPI-KNSPDFQIHTFSTKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             W+++   I K +   ++      +  L I     +D   +  +A N  G   CS +L+V
Sbjct: 977  YWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036

Query: 4501 EE-----------KRRQGRGGIVP------------PSFTLTAQNVNVTSGQLVRLDTKV 4537
            +            +  +GR  +              P F     ++    G+L RLD KV
Sbjct: 1037 QSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV 1096

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKIL-EEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            +G  P ++ WL NG+ V PD  +K+L  E G ++LLI     +D+G Y+C+A N  G+  
Sbjct: 1097 SGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 1156

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               E  V             K     P I+E L++  V EG  +   C+++G P P   W
Sbjct: 1157 FSLELSV-----------VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYW 1205

Query: 4657 YKGDKLIKPSK-YFQMSRTADEYT-LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             K ++ I  ++    M +    Y  L I  A   D G Y   A N AG V+  A+L +
Sbjct: 1206 KKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 67/234 (28%), Positives = 98/234 (41%), Gaps = 13/234 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGY 1767
            AP+F   +K  RV E     F  +++ +  PK  V W ++G  I   N    M     G 
Sbjct: 944  APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPK--VYWFKDGKQISKRNEHCKMRREGDGT 1001

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+++    +D G YT  A N  G    S  L VQS   L + S+  SA Q  +     
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---LPIRSRLTSAGQSHR---GR 1055

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-V 1886
            SR Q R+   +          Q  G     EG+    +C++   P P +   W  NG+ V
Sbjct: 1056 SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 1113

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            L          + G  +L I  +   D+G Y C A N  GQ   S+ L+V +KE
Sbjct: 1114 LPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 64/266 (24%), Positives = 111/266 (41%), Gaps = 30/266 (11%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P+F ++  +  V EG  V L+   VG P P++ W  +G  +  +P++ I   G   +L I
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328

Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXX-----XQKRLHLPRPTKVXXXX 605
             A   D   Y C A N+ G+ +T A +Y               ++   + +P +V    
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 388

Query: 606 XXXXXXXXYLRHVER--ARP-------------YIPPGEEDRVYPPPQFIVPLKSVTAME 650
                    +   +   A+P             Y+   +   +   P F   L++++A E
Sbjct: 389 TTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASE 448

Query: 651 GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--------FGYISLDMLSLN 702
           G  + FE R++  G P+ K+EW + G  IE S  F  + +            +L +  + 
Sbjct: 449 GQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVF 506

Query: 703 IQDSGEYTCRAVSATGVAETKAVLHV 728
            +DSG +TC A +  G   + A LHV
Sbjct: 507 AEDSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 80/310 (25%), Positives = 130/310 (41%), Gaps = 21/310 (6%)

Query: 2941 PDLKIEWYFNGK-VLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P  K+ W+ +GK + ++    K+  +  G  +L +      D G YT  A N +G    S
Sbjct: 972  PVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCS 1031

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
              +   S       T   +   G  ++Q  +    KEP Q+        P F     D+V
Sbjct: 1032 GHLMVQSLPIRSRLTSAGQSHRGRSRVQERD----KEPLQE----RFFRPHFLQAPGDMV 1083

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTT 3116
               EG++   +  +  +G     + W  NG+ +  +ASH++  V   G+  L I      
Sbjct: 1084 -AHEGRLCRLDCKV--SGLPPPELTWLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQR 1139

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D+GTY C ATNK GQ   S++L  V K   + P     +QN  G+ +G     EC V+ +
Sbjct: 1140 DAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNC-GVPEGHPVRLECRVIGM 1198

Query: 3177 DDPDMKIEWYHNGQPMRHS-TRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P     W  + + +  +  RI    D  G+  L I   +  D+G Y   A N+ G   
Sbjct: 1199 PPP--VFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVS 1256

Query: 3235 TRATINCYGK 3244
              A ++ Y +
Sbjct: 1257 CTARLDIYAQ 1266



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 76/276 (27%), Positives = 125/276 (45%), Gaps = 26/276 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH---RFKTTYDFGY 2034
            P F K +K+  VTEG PV     +  +  P  +V W+ +G+ + + +   + +   D G 
Sbjct: 945  PIFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGD-GT 1001

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA---KSGLYLDTLDEQRLKKIQEL 2091
             +L I    ++D G Y   A N  G    +  + V +   +S L       +   ++QE 
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQER 1061

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
            +K    +P++E     RP FL A   +    EG     +C+V  +  P LT  W  NGQ 
Sbjct: 1062 DK----EPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQP 1112

Query: 2152 IR--AGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
            +   A H+     + G  +L I      D+GTY C ATNK G+  N+ +L+++     + 
Sbjct: 1113 VLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ--NSFSLELSVVAKEV- 1168

Query: 2210 DTQHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRF 2244
              + P  LEK++     +GH  R+E     + PP F
Sbjct: 1169 -KKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVF 1203



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 75/311 (24%), Positives = 128/311 (41%), Gaps = 22/311 (7%)

Query: 3349 EENSGEYECVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKLQTLEDSMVR 3406
            ++N  E +      LG+  T ++++   +E  I   + +L   +E  LE+    E     
Sbjct: 873  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLERTPVDESDDEI 932

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            + D  +   K  AP+F   L +   + EG    F  ++     P  KV W+ +GK +   
Sbjct: 933  QHD-EIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKR 988

Query: 3467 S---RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            +   + R   D G   L I  T  +D G Y   A N  G    +  + VQ   ++ + S+
Sbjct: 989  NEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQ---SLPIRSR 1044

Query: 3524 LPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIP 3583
            L    +    +    E          P  E    P F   P D++  E      +C++  
Sbjct: 1045 LTSAGQSHRGRSRVQERDK------EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSG 1098

Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEAT 3642
            +    +   W  NG+P+L  +  K  + + G   L I  + QRDAG Y C ATN+ G+ +
Sbjct: 1099 LPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 1156

Query: 3643 VSCKLQVKGRQ 3653
             S +L V  ++
Sbjct: 1157 FSLELSVVAKE 1167



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 46/290 (15%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            +E + Q P FT  ++   V E      +   I VG P  +V W   G  +E S  +  + 
Sbjct: 262  EEPLGQPPRFTQKLRSREVPEGTRVQLDC--IVVGIPPPQVRWYCEGKELENSPDIHIVQ 319

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ-HESALQKIQ 1822
                 +L +     ED+G Y+C A N  G   TS+ ++++  +S   E   ++  + +IQ
Sbjct: 320  AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQ 379

Query: 1823 Q-LEDSSRYQRREDVEVAVNQA------PRFIT--QLNGPTKLSEG-------------- 1859
            +  E SS       +  AV QA      PR  T  Q   PT   +G              
Sbjct: 380  KPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTK 439

Query: 1860 ----------QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR--------TSNDFGF 1901
                      Q   +ECR++  P P  +VEWY  G +++    +R         +     
Sbjct: 440  MLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPEEI 497

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
              L I  V+ EDSG +TC A N  G   S  +L+V+  E +  +    SA
Sbjct: 498  CTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 547



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 31/99 (31%), Positives = 53/99 (53%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP   + L+ + V EG  ++  C +VG P P V+WY   K ++ S    + +  + ++L 
Sbjct: 268  PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            I+EAF ED G Y C A N  G  + +A++ +     +D+
Sbjct: 328  IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDS 366



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--- 4467
            P+FTK +Q     E +   FE    G P P ++WYRE   I++SPDF+I     +S+   
Sbjct: 435  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494

Query: 4468 -----LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
                 L+I +VF EDS  F   A N+ GT    A L V
Sbjct: 495  EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 12/152 (7%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--------MS 4672
            A P   + L++   +EGQ + F C++ G P P V+WY+   LI+ S  F+        M+
Sbjct: 433  AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 492

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN---LPALTPLRD 4729
               +  TL I+E F ED G + C A N  G V+  A+L V   +   N   L +     +
Sbjct: 493  EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 552

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            +   E QP+   ++  S  +P    L EG L+
Sbjct: 553  LAAIEPQPSPPHSEPPSVEQPPKPKL-EGVLV 583



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 72/256 (28%), Positives = 109/256 (42%), Gaps = 28/256 (10%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTLNDFG 3751
            P F   +K +  V EG PV F C++  VG P  ++ WF +G+  +  +   ++    D G
Sbjct: 945  PIFDKRLK-HFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGD-G 1000

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
              +L I+   + D G YT  A N  G      +I+CS    +V    +   ++       
Sbjct: 1001 TCSLHIESTTSDDDGNYTIMAANPQG------RISCSGHL-MVQSLPIRSRLTSAGQSHR 1053

Query: 3812 ERGRISDAPKEEPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
             R R+ +  KE P+      P F+         E    R +C+V     P+L   W  NG
Sbjct: 1054 GRSRVQERDKE-PLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNG 1110

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS-----CKK 3923
            + +LP       V + G  SL I  +   D+G Y C A N  G++     +S      KK
Sbjct: 1111 QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK 1170

Query: 3924 LPDII--LQN-QVPRG 3936
             P I+  LQN  VP G
Sbjct: 1171 APVILEKLQNCGVPEG 1186



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 70/266 (26%), Positives = 119/266 (44%), Gaps = 30/266 (11%)

Query: 1168 QIEEISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            Q +EI   K   P+F + L +   V+EG  +   C++  +G P  +V WF +G+ ++  +
Sbjct: 933  QHDEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRN 989

Query: 1225 ---RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE---RSDIVTD 1278
               + +   D G  +L I   TS D G YT+ A N  G    S  + V     RS + + 
Sbjct: 990  EHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSA 1048

Query: 1279 TQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVG 1338
             Q+ +   ++Q  +    + +  R        P F +A  ++   EG    L+C++   G
Sbjct: 1049 GQSHRGRSRVQERDKEPLQERFFR--------PHFLQAPGDMVAHEGRLCRLDCKVS--G 1098

Query: 1339 DQTMRVEWFCNGKPI--KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                 + W  NG+P+     H+     E    +L +  +   D+G Y C ATN+ G+   
Sbjct: 1099 LPPPELTWLLNGQPVLPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSF 1157

Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQ 1422
            S  L V+AK+      + P  LEK+Q
Sbjct: 1158 SLELSVVAKE----VKKAPVILEKLQ 1179



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 63/230 (27%), Positives = 95/230 (41%), Gaps = 15/230 (6%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI-KTGHRFRPAYEFDYV 1368
            AP F + L +    EG+ V   C++  VG    +V WF +GK I K     +   E D  
Sbjct: 944  APIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001

Query: 1369 -ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
             +L + S   +D G YT  A N  G    S  L V   + L + S+  S  +  +     
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQSHRGRSRV 1058

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
                K  + +     +P F+  P  +    EG+    +CK+  +    L   W  NGQPV
Sbjct: 1059 QERDKEPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 1113

Query: 1488 T--IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
                 H+   + + G  +L I  L   D+G Y C A N  G +  S  L+
Sbjct: 1114 LPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELS 1162



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 61/237 (25%), Positives = 100/237 (42%), Gaps = 13/237 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694
            P F   LK     EG  + F  +I  VG P  K+ W K+G+ I   +    + R G    
Sbjct: 945  PIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTC 1002

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            SL + S    D G YT  A +  G       L V       R +   ++ +   ++++  
Sbjct: 1003 SLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERD 1062

Query: 755  KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT 814
            K    E ++E+   RP F++   D+    EGR    + +++ +  P +   W  +G+P+ 
Sbjct: 1063 K----EPLQERFF-RPHFLQAPGDM-VAHEGRLCRLDCKVSGLPPPELT--WLLNGQPVL 1114

Query: 815  A-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
              +S    +   G  SL I  L   DAG+Y   A NK G+   +  + V A+    A
Sbjct: 1115 PDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKA 1171



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 7/105 (6%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F K+ Q+   +EG++  F+CRV G P P+V W+     I D  + +IL  +  + A 
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493

Query: 450 ------LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
                 L+I  V   DSG  TC A NK G  +   +L+V   E +
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 3/98 (3%)

Query: 3688 EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            E+    PPRFT +++   +VPEG  V  DC V  VG P  ++ W+  G+       +H +
Sbjct: 262  EEPLGQPPRFTQKLRSR-EVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIV 318

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                  +L I   +  D G Y+C A+N +G+ +T+A+I
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 62/244 (25%), Positives = 97/244 (39%), Gaps = 13/244 (5%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            LE+    ES +  +  EIP       P+F + L++   + EG    F C++  VG P  K
Sbjct: 920  LERTPVDESDDEIQHDEIPTGKCIA-PIFDKRLKHF-RVTEGSPVTFTCKI--VGIPVPK 975

Query: 2410 VEWFRNEKLIEDSSRITKTH--DFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            V WF++ K I   +   K      G  S+ I     +D+G Y   A+N  G         
Sbjct: 976  VYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 1035

Query: 2468 XXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAH 2527
                  + + ++     +  +   +  ER  E     F +P F Q   G     EG+   
Sbjct: 1036 VQS---LPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQA-PGDMVAHEGRLCR 1091

Query: 2528 YEARVVPVGDPSLRFEWYINGVE-LKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAI 2586
             + +V  +  P L   W +NG   L   S      + G  +L I+ +   DAG Y C A 
Sbjct: 1092 LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIAT 1149

Query: 2587 NRAG 2590
            N+ G
Sbjct: 1150 NKTG 1153



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 60/226 (26%), Positives = 102/226 (45%), Gaps = 19/226 (8%)

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS---RVKTINDFGFVILEIGGVYQR 3625
            ++E S   F C+++ +     +V WF +GK +   +   +++   D G   L I      
Sbjct: 956  VTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSD 1012

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEI 3685
            D G YT  A N  G  + S  L V   Q + +  +L S  +S      +    + +R++ 
Sbjct: 1013 DDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQS-----HRGRSRVQERDKE 1064

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP-FATGSRV 3744
             ++ E+   P F ++   ++   EG     DC+V   G P   + W  NG+P     S  
Sbjct: 1065 PLQ-ERFFRPHF-LQAPGDMVAHEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHK 1120

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              + + G  +L ID +  RDAG Y C ATNK G  + + +++  AK
Sbjct: 1121 MLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 1166



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 74/303 (24%), Positives = 115/303 (37%), Gaps = 46/303 (15%)

Query: 3413 EEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF 3472
            EE  G+ P FT  L + E + EG     +  +     P  +V WY  GK L+        
Sbjct: 262  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIV 318

Query: 3473 CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTI 3532
                   L I+  + ED+G Y C A N YG   T+A + ++G  +   E    K     I
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRI 378

Query: 3533 DK---IAALEGYSGTVDTLTPEAE------------------------SGNP----PEFT 3561
             K   +++    S  +    P+A+                         G P    P FT
Sbjct: 379  QKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFT 438

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG-----KP---LLTGSRVKTINDFG 3613
                +L  SE     FECR+      S +VEW+  G      P   +L            
Sbjct: 439  KMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEE 496

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ 3673
               L I  V+  D+G +TC A+N++G  +   +L V+G + +     L  H  + T ++ 
Sbjct: 497  ICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSL--HSANSTTNLA 554

Query: 3674 KLE 3676
             +E
Sbjct: 555  AIE 557



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 60/242 (24%), Positives = 103/242 (42%), Gaps = 17/242 (7%)

Query: 1571 DEVTTQ---APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            DE+ T    API    LK+  + EG    F  +++ +     KV W+ + K +   +   
Sbjct: 935  DEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIP--VPKVYWFKDGKQISKRNEHC 992

Query: 1628 ETNNFG--FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
            +    G    +L I S   +D G YT  A N  G    SG  +V   +S+ + S+   A 
Sbjct: 993  KMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAG 1049

Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
                      +  +   Q+      P F     D+   E +    + ++  +  P+L   
Sbjct: 1050 QSHRGRSRVQERDKEPLQERFF--RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL--T 1105

Query: 1746 WLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            WL NG P+  +AS+++  + + G  +L +  +   D+GTY C A N+ G+   S  L V 
Sbjct: 1106 WLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVV 1164

Query: 1804 SK 1805
            +K
Sbjct: 1165 AK 1166



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 40/122 (32%), Positives = 57/122 (46%), Gaps = 8/122 (6%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTYT 4570
            PP FT   ++  V  G  V+LD  V G  P  V W   GK+++  PDI   I++    ++
Sbjct: 268  PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIH--IVQAGNLHS 325

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAEC----VVSLPATKDKPKPQTKAANAPPEII 4626
            L I EA+ +D+G+Y C A N  G     AE     V S  +  D  K +      P E+ 
Sbjct: 326  LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVS 385

Query: 4627 EP 4628
             P
Sbjct: 386  SP 387



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 9/145 (6%)

Query: 3146 GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG 3205
            GQ PRFT  +++ E + +G     +C VV +  P  ++ WY  G+ + +S  I  V    
Sbjct: 266  GQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQAGN 322

Query: 3206 FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELES 3265
               L IA     D+G Y C A N YG D T A I   G     + S   +      E+  
Sbjct: 323  LHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG-----VSSSDSEGDPNKEEMNR 377

Query: 3266 LQGAQQ-QTPSTPSAEPPKFITQIQ 3289
            +Q   +  +P T SA  P  + Q Q
Sbjct: 378  IQKPNEVSSPPTTSAVIPPAVPQAQ 402



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 49/164 (29%), Positives = 74/164 (45%), Gaps = 12/164 (7%)

Query: 2235 EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT 2294
            EEP   PPRF  +LR +  V EG     +C V  +  P +R  +Y  GK L+++   HI 
Sbjct: 262  EEPLGQPPRFTQKLR-SREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 2295 FDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  SL I     ED G YS  A N  G  T + S  +  +G   S+S+     E++ 
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYG--TDSTSAEIYIEGVSSSDSEGDPNKEEMN 376

Query: 2355 ELE-----SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQT 2393
             ++     S+ P     IP  V + + +  QP   +  IQ+ Q+
Sbjct: 377  RIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQP--RVATIQQCQS 418



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 6/159 (3%)

Query: 4343 QKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE 4402
            ++  +P P  +     EV+ A ++Q  K     +E  +  +     +    +       E
Sbjct: 207  ERSSVPIPIPADTRDNEVNHALEQQEAKR----REAEQAASEAAGGDTTPGSSPSSLYYE 262

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
             P+   +PP FT+K++   V E  + + +    G P P ++WY E   ++NSPD  I   
Sbjct: 263  EPL--GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQA 320

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
                 L I + F ED+  ++  A N  GT   SA + +E
Sbjct: 321  GNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 36/135 (26%), Positives = 60/135 (44%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+  QK R+ ++ EG   Q    + G P P+V W+  G+ L NS    I+   N  +L 
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +    + D+G Y+  A N  G   TS  + +E  + S  +   ++   +  Q+  E    
Sbjct: 328 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSP 387

Query: 385 ISEKALAPQFVKVCQ 399
            +  A+ P  V   Q
Sbjct: 388 PTTSAVIPPAVPQAQ 402



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
            EEP+   PP+F  +++S  V E   V+ +C V     P++R  WY  GK L +      V
Sbjct: 262  EEPL-GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
                  SL I   + ED+G Y C A N +G D T A I
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 8/93 (8%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--------L 4778
            L+++   EGQ   F+ ++     P ++W REG LI ++PDF+++ +   ++        L
Sbjct: 441  LQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTL 500

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +I   + ED+G FTC A+   G V + A+L V+
Sbjct: 501  VIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVR 533



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 15/222 (6%)

Query: 3985 LVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY--DFGYVAMNFGWVYPED 4042
            + E     F C++  VG P  KV WF +GK +  +N    +     G  +++      +D
Sbjct: 956  VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDD 1013

Query: 4043 SGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             G Y   A N  G       +     P       +   + S  +     +  Q   ++ +
Sbjct: 1014 DGNYTIMAANPQGRISCSGHLMVQSLP-------IRSRLTSAGQSHRGRSRVQERDKEPL 1066

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY- 4161
            +E   R  P F+  P  +   EG   R  C+V+G P P + WLLNG  ++  + +K+   
Sbjct: 1067 QERFFR--PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 1124

Query: 4162 -DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
              G++   I    Q D G  + I             L V+ +
Sbjct: 1125 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 1166



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            + P+F + +++ EV EG  V L+  +  +  P +R  WYC G+ ++              
Sbjct: 267  QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIVQAGNLH 324

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD-TLDEQRLKKIQELEKY 2094
            +L I  A+ EDTG Y C A+N  G   T++ + ++  S    +   +++ + +IQ+  + 
Sbjct: 325  SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEV 384

Query: 2095 ERP 2097
              P
Sbjct: 385  SSP 387



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 68/275 (24%), Positives = 113/275 (41%), Gaps = 26/275 (9%)

Query: 751  EDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG 810
            E   + QH E I       P F + L+    + EG    F  ++  +  P  +V W+KDG
Sbjct: 927  ESDDEIQHDE-IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGI--PVPKVYWFKDG 982

Query: 811  RPITASSRITSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
            + I+  +    +   G    SL+I    ++D G+YT+ A N  G    +  + V +    
Sbjct: 983  KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---- 1038

Query: 869  TADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
                 +P + R +                    + E   +P F     D ++  EG    
Sbjct: 1039 -----LPIRSR-LTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVA-HEGRLCR 1091

Query: 929  FEARLEPIGDSTLRVEWLKDGRPV--EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
             + ++  +    L   WL +G+PV  +AS ++      G  +L I  +T  DAG Y C A
Sbjct: 1092 LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVR-ETGVHSLLIDPLTQRDAGTYKCIA 1148

Query: 987  YNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             N  GQ + S  L++V K+      + P  LEK+Q
Sbjct: 1149 TNKTGQNSFSLELSVVAKE----VKKAPVILEKLQ 1179



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 59/237 (24%), Positives = 95/237 (40%), Gaps = 19/237 (8%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVS 2832
            +F   L +    EG  + F C +     P  K+ WF + K +     +           S
Sbjct: 946  IFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 1003

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE 2892
            L I  T  +D G YT  A N +G  + SG L            Q    ++ L +  Q+  
Sbjct: 1004 LHIESTTSDDDGNYTIMAANPQGRISCSGHLM----------VQSLPIRSRLTSAGQSHR 1053

Query: 2893 ARLAKGRRPSVPDTE-YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNG 2951
             R     R   P  E + +P + +    +    EG++  L+ +V     P+L   W  NG
Sbjct: 1054 GRSRVQERDKEPLQERFFRPHF-LQAPGDMVAHEGRLCRLDCKVSGLPPPEL--TWLLNG 1110

Query: 2952 K-VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
            + VL   S   L  + G  +L +  + +RD+G Y C A NK G+   S  +   +K+
Sbjct: 1111 QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P+F++ L + E  EGT V L+C +  VG    +V W+C GK ++           +  
Sbjct: 267  QPPRFTQKLRSREVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQAGNLH 324

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L +   + ED+G Y+C A+N  G   TS  + +
Sbjct: 325  SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 8/103 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
           K  + AP F +    L+  EG+ VV   R  G P+P++ W ++G  I  +P+ RI     
Sbjct: 429 KPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKP 488

Query: 545 AS--------TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            S        TL I    A D+  + CTA N  G+ ++ A+L+
Sbjct: 489 RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLH 531



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 7/161 (4%)

Query: 3965 YDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTP 4024
            Y+    QPPRF  +++S+      E T+ +     VG P  +V W+  GK L +      
Sbjct: 261  YEEPLGQPPRFTQKLRSREV---PEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI 317

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSI 4084
            +      ++     + ED+G Y C A+N+YG D T A I   G      DS+   + + +
Sbjct: 318  VQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEM 375

Query: 4085 EKIRE-MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEE 4124
             +I++  E S   T   V+  +  +   + V+ P   T+++
Sbjct: 376  NRIQKPNEVSSPPTTSAVIPPAVPQAQHL-VAQPRVATIQQ 415



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 10/110 (9%)

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR------ 1360
            ++ AP F++ L N+   EG  V  ECR++  G  + +VEW+  G  I+    FR      
Sbjct: 431  IIAAPVFTKMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKP 488

Query: 1361 --PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
               A   +   L +  V+ EDSG +TC A+N+ G   +   L V   +DL
Sbjct: 489  RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 37/91 (40%), Positives = 49/91 (53%), Gaps = 11/91 (12%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKTHDFGY 2433
            PVFT+ LQN+ +  EGQ   F+CR+   G P+ KVEW+R   LIEDS   RI +      
Sbjct: 435  PVFTKMLQNL-SASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 2434 V------SMTISHVRDEDEGVYMCRASNLLG 2458
                   ++ I+ V  ED G + C ASN  G
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 23/238 (9%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM---RHSTRIKTVSDFG 3205
            P F   +++   + +G    F C +V +  P  K+ W+ +G+ +       +++   D G
Sbjct: 945  PIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCKMRREGD-G 1000

Query: 3206 FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDS-LAKIRELE 3264
               L I  T + D G Y   A N  G       I+C   G + ++SL   S L    +  
Sbjct: 1001 TCSLHIESTTSDDDGNYTIMAANPQGR------ISC--SGHLMVQSLPIRSRLTSAGQSH 1052

Query: 3265 SLQGAQQQTPSTPSAEP---PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321
              +   Q+    P  E    P F+    D+    EG+    + ++  +  P+L   W  N
Sbjct: 1053 RGRSRVQERDKEPLQERFFRPHFLQAPGDMVAH-EGRLCRLDCKVSGLPPPELT--WLLN 1109

Query: 3322 GKK-LPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            G+  LP         + G+  L I    + ++G Y+C+ATNK G++S    L   +KE
Sbjct: 1110 GQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 57/214 (26%), Positives = 98/214 (45%), Gaps = 25/214 (11%)

Query: 1077 VEWYFNGKQITSAN---RIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            V W+ +GKQI+  N   +++   D G  +L I S  ++D G YT++A N  G    S  +
Sbjct: 976  VYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 1034

Query: 1134 TVET---RSSIDTS-SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPV 1189
             V++   RS + ++   HRG   ++R  E  K  EP+ +       +P F+Q        
Sbjct: 1035 MVQSLPIRSRLTSAGQSHRG---RSRVQERDK--EPLQE----RFFRPHFLQ-APGDMVA 1084

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGFVALDIIHATSADTG 1248
             EG+   L+C++   G P   + W  NG+ V   +  K    + G  +L I   T  D G
Sbjct: 1085 HEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAG 1142

Query: 1249 EYTVRAVNHLG----SAHTSAIVRVIERSDIVTD 1278
             Y   A N  G    S   S + + ++++ ++ +
Sbjct: 1143 TYKCIATNKTGQNSFSLELSVVAKEVKKAPVILE 1176



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 27/85 (31%), Positives = 42/85 (49%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            LR   V EG   Q    +     P ++W  EG  +  +PD  ++  GN   L I   +EE
Sbjct: 275  LRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEE 334

Query: 4787 DTGTFTCRATTAAGQVETSAKLVVK 4811
            DTG ++C A+   G   TSA++ ++
Sbjct: 335  DTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 34/221 (15%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT--THNHTTL 323
            P   Q P +    EG   +   ++SG P P +TW  NGQ ++    H+++   T  H+ L
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                TQ+ D+G Y         CI T+                     T       E  +
Sbjct: 1133 IDPLTQR-DAGTYK--------CIATNK--------------------TGQNSFSLELSV 1163

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
               E   AP  ++  Q+  V EG   R +CRV G P P V ++  D +       +I ++
Sbjct: 1164 VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMP-PPVFYWKKDNETIPCTRERISMH 1222

Query: 444  E--SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            +  +G   L+I     SD+G  T  A+N++G  +   RL++
Sbjct: 1223 QDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 33/112 (29%), Positives = 49/112 (43%)

Query: 50   TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
            T V+ S D         G+   PIF++  K+ R  +G    F  K+ G P P V W +  
Sbjct: 923  TPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDG 982

Query: 110  APLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              + + N++     E  G  SL I+     D+G YT  A N  G   CS ++
Sbjct: 983  KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 1034



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 12/145 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG--- 3751
            P FT ++  N+   EG  V F+CRV+  G P+ +++W+  G           L       
Sbjct: 435  PVFT-KMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 3752 -----FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
                    L I  ++A D+G +TC A+NK+G+ ++ A++      D+     L    S  
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTT 551

Query: 3807 KIKELERGRISDAPKEEPIVSTPPK 3831
             +  +E  + S    E P V  PPK
Sbjct: 552  NLAAIE-PQPSPPHSEPPSVEQPPK 575



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 104/250 (41%), Gaps = 22/250 (8%)

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276
            LE+    E+       E+   K   P F   L+    V EG    F C++  +  P  ++
Sbjct: 920  LERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KV 976

Query: 2277 EFYHNGKALQSAARFHITF---DFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAIS 2331
             ++ +GK + S    H        G  SL I+    +D G Y++ A N  G   C+  + 
Sbjct: 977  YWFKDGKQI-SKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 1035

Query: 2332 M-TVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390
            + ++  +  + S  Q   G  +++E +  EP +           RP F Q   ++    E
Sbjct: 1036 VQSLPIRSRLTSAGQSHRGRSRVQERDK-EPLQERFF-------RPHFLQAPGDMV-AHE 1086

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            G+    DC++   G P  ++ W  N + ++ D+S      + G  S+ I  +   D G Y
Sbjct: 1087 GRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 1144

Query: 2450 MCRASNLLGE 2459
             C A+N  G+
Sbjct: 1145 KCIATNKTGQ 1154



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 57/231 (24%), Positives = 89/231 (38%), Gaps = 13/231 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG---AR 2690
            + TG   APIF   LK + ++ EG  V    ++     P  K+ WFK+G  ++      +
Sbjct: 937  IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCK 993

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            ++   D G  +L I S  +DD G YT  A N  G    +  + ++     +   L     
Sbjct: 994  MRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSAGQ 1050

Query: 2751 DRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWF 2810
               G                     F+    ++V  EG     +C V  S  P  ++ W 
Sbjct: 1051 SHRGR-SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV--SGLPPPELTWL 1107

Query: 2811 FNNKP-LPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
             N +P LP  +      +    SL I    + D+G Y C ATN  G  + S
Sbjct: 1108 LNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFS 1158



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 4/117 (3%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            Q P FTQ L++ + + EG     DC  I VG P  +V W+   K +E+S  I        
Sbjct: 267  QPPRFTQKLRSRE-VPEGTRVQLDC--IVVGIPPPQVRWYCEGKELENSPDIHIVQAGNL 323

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE-TQHPEGMKKIQK 2489
             S+TI+   +ED G Y C ASN+ G                  E   + E M +IQK
Sbjct: 324  HSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQK 380



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 14/151 (9%)

Query: 1678 ESQHEGALPR---LNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARL 1734
            ++QH  A PR   + Q +  + Y +     + I  APVFT  ++++  +E Q   FE R+
Sbjct: 400  QAQHLVAQPRVATIQQCQSPTNYLQ-GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRV 458

Query: 1735 IPVGDPKLRVEWLRNGVPIEAS-------NRLTTMHDFGYV-ALNMKYVNPEDSGTYTCR 1786
               G P  +VEW R G  IE S        +  +M +   +  L +  V  EDSG +TC 
Sbjct: 459  --KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCT 516

Query: 1787 AINELGEAVTSSTLFVQSKASLQLESQHESA 1817
            A N+ G   + + L V+    L       SA
Sbjct: 517  ASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 547



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIR----- 4559
            G+  I  P FT   QN++ + GQLV  + +V G     V W + G  ++  PD R     
Sbjct: 428  GKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKK 487

Query: 4560 -NKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
               + E +   TL+I E + +DSG + C A N  G
Sbjct: 488  PRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 43/149 (28%), Positives = 62/149 (41%), Gaps = 13/149 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APVFT  L N+ +  EG+   FE R+     P  KVEWY  G  ++    FR        
Sbjct: 434  APVFTKMLQNL-SASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRS 490

Query: 3479 ILE--------ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530
            + E        I+  + EDSG + C A N YG   + A + V+G  ++     L      
Sbjct: 491  MAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANST 550

Query: 3531 TIDKIAALEGYSGTVDTLTPEAESGNPPE 3559
            T   +AA+E       +  P  E    P+
Sbjct: 551  T--NLAAIEPQPSPPHSEPPSVEQPPKPK 577



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P  +PP+F  +++   ++ EG     +  +V +  P  +V W+  GK+L +         
Sbjct: 264  PLGQPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQA 320

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              +  L I   +EE++G Y C A+N  G DST A +
Sbjct: 321  GNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 3/82 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HAL 450
           P+F +  + R+V EG   + DC V G P P+V W+   +++ +  +  I + ++GN H+L
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELEN--SPDIHIVQAGNLHSL 326

Query: 451 MITNVTLSDSGVVTCVARNKSG 472
            I      D+G  +C A N  G
Sbjct: 327 TIAEAFEEDTGRYSCFASNIYG 348



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 11/97 (11%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            +PI++ P  F   +++ +  E + V FECRV+    PK  +EWYR G L+     +R + 
Sbjct: 429  KPIIAAPV-FTKMLQNLSASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQ 485

Query: 3883 DMG--------FVSLDILYVYAEDSGEYICRAVNDFG 3911
                         +L I  V+AEDSG + C A N +G
Sbjct: 486  KKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 73/303 (24%), Positives = 116/303 (38%), Gaps = 47/303 (15%)

Query: 2870 NIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYP--KPEWIIPIAAEHQLVEGQ 2927
            N   + Q  + +   +A  +A       G  PS    E P  +P          ++ EG 
Sbjct: 225  NHALEQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGT 284

Query: 2928 VLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCK 2987
             + L+  V     P  ++ WY  GK LE      +       +L + + +E D+G Y+C 
Sbjct: 285  RVQLDCIVV--GIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCF 342

Query: 2988 AYNKRGEAFTSSTVY---CTSKDN-------LIERTQHPKGTE-----------GLEKIQ 3026
            A N  G   TS+ +Y    +S D+        + R Q P                + + Q
Sbjct: 343  ASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQ 402

Query: 3027 NLEDSLRKEPGQQPDDDT-------GRP----PEFTTVFKDIVDISEGQIAHYEASLIPT 3075
            +L    R    QQ    T       G+P    P FT + +++   SEGQ+  +E  +   
Sbjct: 403  HLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNL-SASEGQLVVFECRV--K 459

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVY--------AFGMVVLEILGTKTTDSGTYSCRATN 3127
            G  S  +EW+  G  IE S   R +            +  L I      DSG ++C A+N
Sbjct: 460  GAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASN 519

Query: 3128 KWG 3130
            K+G
Sbjct: 520  KYG 522



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 5/123 (4%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            E  + Q PRF  +L    ++ EG     +C +   P P +R  WY  GK L++       
Sbjct: 262  EEPLGQPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
                  +L I   + ED+G Y+C A N  G   +S  + ++   S   DS+ +   E++ 
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMN 376

Query: 1957 YLE 1959
             ++
Sbjct: 377  RIQ 379



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 18/143 (12%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG--- 3205
            P FT  +QN+    +GQ   FEC V     P  K+EWY  G  +  S   + +       
Sbjct: 435  PVFTKMLQNLSA-SEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 3206 -----FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD-SLAK 3259
                    L IA     DSG + C A NKYG   + A ++  G      E L  + SL  
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGN-----EDLSNNGSLHS 546

Query: 3260 IRELESLQGAQQQTPSTPSAEPP 3282
                 +L   + Q PS P +EPP
Sbjct: 547  ANSTTNLAAIEPQ-PSPPHSEPP 568



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 21/142 (14%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-------- 2160
            PVF   L +L +  EG    FECRV+    P   ++W+  G  I     +R         
Sbjct: 435  PVFTKMLQNL-SASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKI 2220
                    L I   +AEDSG + C A+NK G   +   L V G+ ++       NG    
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL-----SNNG---- 542

Query: 2221 RQLEAQGHSTRIEVEEPKISPP 2242
              L +   +T +   EP+ SPP
Sbjct: 543  -SLHSANSTTNLAAIEPQPSPP 563



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 10/99 (10%)

Query: 64  GRPGEP--SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE------- 114
           G  G+P  + P+F ++ +N   ++G    FE +++G P+P V W R +  L+E       
Sbjct: 425 GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYR-EGTLIEDSPDFRI 483

Query: 115 CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
             K      E     +L+I ++   D G +TCTA N+YG
Sbjct: 484 LQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 10/105 (9%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--------STH 2826
            VF   L N+   EG  + FEC V+ +  P  K+EW+     +     ++           
Sbjct: 436  VFTKMLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAE 493

Query: 2827 DFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
                 +L I   + EDSG +TC A+N  G+ ++   L   G++++
Sbjct: 494  PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+V +EG+  +   +++    P + WL  G  ++P+     ++ E     LLI    + D
Sbjct: 1081 DMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRD 1140

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             GT+ C AT   GQ   S +L V +K
Sbjct: 1141 AGTYKCIATNKTGQNSFSLELSVVAK 1166



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 8/108 (7%)

Query: 3036 PGQQP-----DDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090
            PG  P     ++  G+PP FT   +   ++ EG     +   I  G     + W+  GK 
Sbjct: 252  PGSSPSSLYYEEPLGQPPRFTQKLRSR-EVPEG--TRVQLDCIVVGIPPPQVRWYCEGKE 308

Query: 3091 IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            +E S  I  V A  +  L I      D+G YSC A+N +G    S ++
Sbjct: 309  LENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 63/232 (27%), Positives = 90/232 (38%), Gaps = 17/232 (7%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH-- 1491
            D I     I P F  R K    V EG  V F CK+  +     KV WFK+G+ ++  +  
Sbjct: 935  DEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEH 991

Query: 1492 -RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             + R   D G  +L I    ++D G YT  A N  G    S  L  +S    +RS    A
Sbjct: 992  CKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSA 1048

Query: 1551 GLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL 1609
            G    Q    RS+    D    +     P    +  ++   EG+    + ++  +    L
Sbjct: 1049 G----QSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL 1104

Query: 1610 KVEWYHNNKP-LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
               W  N +P L   S        G  +L I      D+GTY C A N  G+
Sbjct: 1105 --TWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ 1154



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL--------TSDFGFVTLDLVDV 2976
            EGQ++  E +V  K  P  K+EWY  G ++E    F++               TL + +V
Sbjct: 448  EGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 505

Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL 3009
            +  DSG +TC A NK G   + + ++    ++L
Sbjct: 506  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 7/160 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L +    EG  +  +C V     P  ++ W+   K L +          +  SL I
Sbjct: 271  FTQKLRSREVPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQAGNLHSLTI 328

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               +EED+G Y+C A+N  G+ +TS  +   G  +   D++    K  +  +++  E   
Sbjct: 329  AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMNRIQKPNEVSS 386

Query: 2896 AKGRRPSVPDTEYPKPEWII--PIAAEHQLVEGQVLHLEG 2933
                   +P    P+ + ++  P  A  Q  +    +L+G
Sbjct: 387  PPTTSAVIPPA-VPQAQHLVAQPRVATIQQCQSPTNYLQG 425



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGD 128
            +P I E++ +N    +G   + E ++ G P PV  W +K    + C +  +  + + TG 
Sbjct: 1171 APVILEKL-QNCGVPEGHPVRLECRVIGMPPPVFYW-KKDNETIPCTRERISMHQDTTGY 1228

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
              LLI+     D G YT +A+N+ G   C+
Sbjct: 1229 ACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 2097 PKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            P  +  E+P GQ P F   L S E + EG R   +C V  I  P   + W+  G+++   
Sbjct: 256  PSSLYYEEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPPQ--VRWYCEGKELENS 312

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                        +L I   + ED+G Y C A+N  G    +  + + G
Sbjct: 313  PDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG 360



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 630 EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
           E+ +  PP+F   L+S    EG ++  +  +  VG P  ++ W   G+ +E S     + 
Sbjct: 262 EEPLGQPPRFTQKLRSREVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQ 319

Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
                SL +     +D+G Y+C A +  G   T A +++
Sbjct: 320 AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            +E +   PRF  + +S E V EG  V  +C +  +     +V W+  G+ +        +
Sbjct: 262  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIV 318

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                  +L I +   ED+G Y+C A N+ GTD  S  +
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 11/132 (8%)

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
            +A I++ +S     Q     P    P F   +Q+++   EGQ   FE R+     P  KV
Sbjct: 410  VATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSAS-EGQLVVFECRVKGAPSP--KV 466

Query: 3317 EWFYNGKKLPHGHRYRTFHDFG--------IVILDILYCYEENSGEYECVATNKLGRDST 3368
            EW+  G  +     +R              I  L I   + E+SG + C A+NK G  S+
Sbjct: 467  EWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSS 526

Query: 3369 KANLKCTSKENL 3380
             A L     E+L
Sbjct: 527  IAQLHVRGNEDL 538



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 10/93 (10%)

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG--------YVALDIIDL 1509
            EGQ V FEC+++       KVEW++ G  +     FR +               L I ++
Sbjct: 448  EGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 505

Query: 1510 IAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
             AEDSG +TC A N  GT     +L  R   D+
Sbjct: 506  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF-ATGS 3742
            E+++  ++       +E   N  VPEG PV  +CRV  +G P     W  +      T  
Sbjct: 1160 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV--IGMPPPVFYWKKDNETIPCTRE 1217

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            R+    D  G+  L I      DAG YT  A N+ G  + TA++   A+
Sbjct: 1218 RISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 1266



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 4/140 (2%)

Query: 1571 DEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +E   Q P  T  L++ E+ EG R   +   I V     +V WY   K L++        
Sbjct: 262  EEPLGQPPRFTQKLRSREVPEGTRVQLD--CIVVGIPPPQVRWYCEGKELENSPDIHIVQ 319

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQ 1690
                 +L I     ED+G Y+C A N  G   TS    +    S   +S+ +     +N+
Sbjct: 320  AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMNR 377

Query: 1691 LEDTSKYQRHSAQDEVITQA 1710
            ++  ++         VI  A
Sbjct: 378  IQKPNEVSSPPTTSAVIPPA 397



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 6/122 (4%)

Query: 1170 EEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            EE     P F Q L +   V EG  + L+C +  +G P  +V W+  G+ +         
Sbjct: 262  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIV 318

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV--IERSDIVTDTQNEQAIEQ 1287
                  +L I  A   DTG Y+  A N  G+  TSA + +  +  SD   D  N++ + +
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD-PNKEEMNR 377

Query: 1288 IQ 1289
            IQ
Sbjct: 378  IQ 379



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 2632 MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691
            ++ +  + Q P FT  L+S + + EG  V L+  V     P  ++ W+  G  L     +
Sbjct: 259  LYYEEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDI 315

Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
                   L +L+I     +D+G Y+C A+N+ G   ++A I IE
Sbjct: 316  HIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E  + Q PRF   L+ + ++ EG     +  V         V WY  GK++ ++  I   
Sbjct: 262  EEPLGQPPRFTQKLR-SREVPEGTRVQLDCIVVGIPP--PQVRWYCEGKELENSPDIHIV 318

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
                  +L IA    ED+G Y+  A N  G    SA + +E  SS D+
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDS 366



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 6/123 (4%)

Query: 763 EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822
           EE   Q P+F + L+   E+ EG     +  +  +  P +R  WY +G+ +  S  I  +
Sbjct: 262 EEPLGQPPRFTQKLRSR-EVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP--EQRRY 880
                 SL I     ED G Y+  A N  G   ++A I +   S+  ++ G P  E+   
Sbjct: 319 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSE-GDPNKEEMNR 377

Query: 881 IEK 883
           I+K
Sbjct: 378 IQK 380



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            + ++  + P  +  LQ+ G + EG     E ++  +  P     W KD   I  +    S
Sbjct: 1164 VAKEVKKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERIS 1220

Query: 822  IFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            +     GY  L I   +  DAG YT+ A N+ G    TA + + A+
Sbjct: 1221 MHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 1266



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 11/91 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-------- 2559
            P+FT++L   S   EGQ   +E RV   G PS + EWY  G  ++    FR         
Sbjct: 435  PVFTKMLQNLSAS-EGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 2560 THDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   TL I  V A D+G + C A N+ G
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 522



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G   + + K+ G P P ++W     P++    + M   E TG  SLLI  +   D G Y
Sbjct: 1086 EGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRE-TGVHSLLIDPLTQRDAGTY 1144

Query: 145  TCTARNQYGE 154
             C A N+ G+
Sbjct: 1145 KCIATNKTGQ 1154



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--------TE 1628
            AP+ T  L+N+   EGQ   FE R+      + KVEWY     ++    F        + 
Sbjct: 434  APVFTKMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
                    L I     EDSG +TC A N  G    S IA +H
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG--TVSSIAQLH 531



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            PVF  +   ++  EG+   F CRV G P P+V W   G  I +   +++
Sbjct: 435  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRI 483



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 4/88 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-- 1764
            + +APV    +++  V E      E R+I  G P     W ++   I  +    +MH   
Sbjct: 1168 VKKAPVILEKLQNCGVPEGHPVRLECRVI--GMPPPVFYWKKDNETIPCTRERISMHQDT 1225

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELG 1792
             GY  L ++     D+G YT  A NE G
Sbjct: 1226 TGYACLLIQPAKKSDAGWYTLSAKNEAG 1253



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 1/84 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            +P  +  E     PP F     +  V EG   +  C V G P P+V W   G  + N   
Sbjct: 255  SPSSLYYEEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPD 314

Query: 4157 YKLTYDGMYH-FDIPKTRQYDTGK 4179
              +   G  H   I +  + DTG+
Sbjct: 315  IHIVQAGNLHSLTIAEAFEEDTGR 338



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/101 (22%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ--------RLINSNKHEI 314
           ++ P   +  +N    EG    F+ ++ G P P+V W++ G         R++      +
Sbjct: 432 IAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
                  TL +      DSG +T  A N  G + +   L V
Sbjct: 492 AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT-VGSRFKTYYDF 1232
            K  PV ++ L N   V EG  + LECR+  M  P     W  +  ++     R   + D 
Sbjct: 1169 KKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERISMHQDT 1225

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             G+  L I  A  +D G YT+ A N  G    +A
Sbjct: 1226 TGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTA 1259



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 3/95 (3%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            Q P F   ++ +  + EG     +  +  +G    +V W  +G+ +E S  I        
Sbjct: 267  QPPRFTQKLRSR-EVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQAGNL 323

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +LTI      D G Y+C A N  G  +TSA + I
Sbjct: 324  HSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 37/164 (22%), Positives = 59/164 (35%), Gaps = 11/164 (6%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY---KLTYDGMYHF 4167
            P+F        V EG    F C++ G P P+V W  +G  I   + +   +   DG    
Sbjct: 945  PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRT 4227
             I  T   D G   ++             L V  +    R  L +A +     +   +R 
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV--QSLPIRSRLTSAGQSHRGRSRVQERD 1062

Query: 4228 ETELEKTFEERQVLQRQG-VIDH-----RPELKPKVIKEPETEW 4265
            +  L++ F     LQ  G ++ H     R + K   +  PE  W
Sbjct: 1063 KEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTW 1106



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            + P FTQ L    E+ EG     +  VV +  P +R  WY  G EL+             
Sbjct: 267  QPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIVQAGNL 323

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I      D G Y C A N  G
Sbjct: 324  HSLTIAEAFEEDTGRYSCFASNIYG 348



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129
           PP F Q  ++    +G   + +  + G P P V W  +   L       +    Q G++ 
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI---VQAGNLH 324

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           SL I +    D G Y+C A N YG    S  I  EG
Sbjct: 325 SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG 360



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG-----KP---LLHKNRFTP 4024
            P F   +Q+  S  E +   FEC++   G P+ KVEW+  G      P   +L K   + 
Sbjct: 435  PVFTKMLQN-LSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQL 4077
                    +    V+ EDSG + C A+N YG   + A +   G   +  +  L
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSL 544



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY------ 1230
            PVF + L N    SEG+ +  ECR++  G P+ +VEW+  G  +     F+         
Sbjct: 435  PVFTKMLQNLS-ASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 491

Query: 1231 --DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
                    L I    + D+G +T  A N  G+  + A + V    D+
Sbjct: 492  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538


>AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein
            protein.
          Length = 1320

 Score =  224 bits (547), Expect = 7e-57
 Identities = 123/364 (33%), Positives = 199/364 (54%), Gaps = 9/364 (2%)

Query: 220  DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQE 279
            ++K+ + E RL+ E+ FR  + +  V ESD +I  + +   G    P   ++ ++ ++ E
Sbjct: 902  EYKISSLEQRLMNEIEFR--LERTPVDESDDEIQHD-EIPTGKCIAPIFDKRLKHFRVTE 958

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT--LRVRNTQKSDSGHYT 337
            G+   F  ++ G P P+V WFK+G+++   N+H  +      T  L + +T   D G+YT
Sbjct: 959  GSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYT 1018

Query: 338  LLAENPNGCIVTSGYLAVES-PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            ++A NP G I  SG+L V+S P  S +      +   ++ +E ++   + E+   P F++
Sbjct: 1019 IMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE-PLQERFFRPHFLQ 1077

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
               D    EG++ R DC+V+G P PE+TW +N + +  D +HK+LV E+G H+L+I  +T
Sbjct: 1078 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 1137

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
              D+G   C+A NK+G+ +F   L+V+ KE   AP  +E+     V EG PV L  R +G
Sbjct: 1138 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIG 1197

Query: 517  TPTPRITWQKDGVPI-IPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
             P P   W+KD   I      + +H D  G + L I  AK SDA WY  +A+N AG  + 
Sbjct: 1198 MPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSC 1257

Query: 575  RARL 578
             ARL
Sbjct: 1258 TARL 1261



 Score =  111 bits (266), Expect = 8e-23
 Identities = 83/322 (25%), Positives = 133/322 (41%), Gaps = 22/322 (6%)

Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEE-D 4566
            G  + P F    ++  VT G  V    K+ G     VYW K+GK++     + K+  E D
Sbjct: 940  GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 999

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV-SLPA----------------TK 4609
            GT +L I      D G Y  +A N  G   C    +V SLP                  +
Sbjct: 1000 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1059

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKY 4668
            ++ K   +     P  ++   D +  EG+     CK+ G P P + W   G  ++  + +
Sbjct: 1060 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASH 1119

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              + R    ++L I      D G YKC+A N  G+ + + +L V   +       L  L+
Sbjct: 1120 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQ 1179

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN--AVLLIGNTYEE 4786
            +  V EG P + + ++     P   W ++   IP T +   +H+     A LLI    + 
Sbjct: 1180 NCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKS 1239

Query: 4787 DTGTFTCRATTAAGQVETSAKL 4808
            D G +T  A   AG V  +A+L
Sbjct: 1240 DAGWYTLSAKNEAGIVSCTARL 1261



 Score =  110 bits (264), Expect = 1e-22
 Identities = 106/418 (25%), Positives = 173/418 (41%), Gaps = 55/418 (13%)

Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI 4382
            +DN+ +T+    + + KK+T     P+  E  +   E  +  + + + E        R  
Sbjct: 873  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSLEQRLMNEIEFRLE--------RTP 924

Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
                  EI+H         E P      PIF K+++  RV E     F  +  G P+P +
Sbjct: 925  VDESDDEIQHD--------EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKV 976

Query: 4443 KWYRENFPI-KNSPDFQIHTFSTKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             W+++   I K +   ++      +  L I     +D   +  +A N  G   CS +L+V
Sbjct: 977  YWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036

Query: 4501 EE-----------KRRQGRGGIVP------------PSFTLTAQNVNVTSGQLVRLDTKV 4537
            +            +  +GR  +              P F     ++    G+L RLD KV
Sbjct: 1037 QSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV 1096

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKIL-EEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            +G  P ++ WL NG+ V PD  +K+L  E G ++LLI     +D+G Y+C+A N  G+  
Sbjct: 1097 SGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 1156

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               E  V             K     P I+E L++  V EG  +   C+++G P P   W
Sbjct: 1157 FSLELSV-----------VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYW 1205

Query: 4657 YKGDKLIKPSK-YFQMSRTADEYT-LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             K ++ I  ++    M +    Y  L I  A   D G Y   A N AG V+  A+L +
Sbjct: 1206 KKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 67/234 (28%), Positives = 98/234 (41%), Gaps = 13/234 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGY 1767
            AP+F   +K  RV E     F  +++ +  PK  V W ++G  I   N    M     G 
Sbjct: 944  APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPK--VYWFKDGKQISKRNEHCKMRREGDGT 1001

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+++    +D G YT  A N  G    S  L VQS   L + S+  SA Q  +     
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---LPIRSRLTSAGQSHR---GR 1055

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-V 1886
            SR Q R+   +          Q  G     EG+    +C++   P P +   W  NG+ V
Sbjct: 1056 SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 1113

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            L          + G  +L I  +   D+G Y C A N  GQ   S+ L+V +KE
Sbjct: 1114 LPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 93/341 (27%), Positives = 151/341 (44%), Gaps = 39/341 (11%)

Query: 1922 INNLGQAV--SSIRLNVQS-KESIIRD---SQHESALEKIQYLEDDSRYKRAVQDDSFVV 1975
            I +LG+ +  S +R N Q  K S +     ++ E  LE+    E D      +Q D    
Sbjct: 884  IRDLGKKITFSDVRPNQQEYKISSLEQRLMNEIEFRLERTPVDESDDE----IQHDEIPT 939

Query: 1976 EK---PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH---RFKTT 2029
             K   P F K +K+  VTEG PV     +  +  P  +V W+ +G+ + + +   + +  
Sbjct: 940  GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRRE 997

Query: 2030 YDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA---KSGLYLDTLDEQRLK 2086
             D G  +L I    ++D G Y   A N  G    +  + V +   +S L       +   
Sbjct: 998  GD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRS 1056

Query: 2087 KIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWF 2146
            ++QE +K    +P++E     RP FL A   +    EG     +C+V  +  P LT  W 
Sbjct: 1057 RVQERDK----EPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WL 1107

Query: 2147 HNGQKIR--AGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGH 2204
             NGQ +   A H+     + G  +L I      D+GTY C ATNK G+  N+ +L+++  
Sbjct: 1108 LNGQPVLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ--NSFSLELSVV 1164

Query: 2205 RNIILDTQHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRF 2244
               +   + P  LEK++     +GH  R+E     + PP F
Sbjct: 1165 AKEV--KKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVF 1203



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 80/310 (25%), Positives = 130/310 (41%), Gaps = 21/310 (6%)

Query: 2941 PDLKIEWYFNGK-VLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P  K+ W+ +GK + ++    K+  +  G  +L +      D G YT  A N +G    S
Sbjct: 972  PVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCS 1031

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
              +   S       T   +   G  ++Q  +    KEP Q+        P F     D+V
Sbjct: 1032 GHLMVQSLPIRSRLTSAGQSHRGRSRVQERD----KEPLQE----RFFRPHFLQAPGDMV 1083

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTT 3116
               EG++   +  +  +G     + W  NG+ +  +ASH++  V   G+  L I      
Sbjct: 1084 -AHEGRLCRLDCKV--SGLPPPELTWLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQR 1139

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D+GTY C ATNK GQ   S++L  V K   + P     +QN  G+ +G     EC V+ +
Sbjct: 1140 DAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNC-GVPEGHPVRLECRVIGM 1198

Query: 3177 DDPDMKIEWYHNGQPMRHS-TRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P     W  + + +  +  RI    D  G+  L I   +  D+G Y   A N+ G   
Sbjct: 1199 PPP--VFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVS 1256

Query: 3235 TRATINCYGK 3244
              A ++ Y +
Sbjct: 1257 CTARLDIYAQ 1266



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 65/266 (24%), Positives = 111/266 (41%), Gaps = 30/266 (11%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P+F ++  +  V EG  V L+   VG P P++ W  +G  +  +P++ I   G   +L I
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328

Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXX-----XQKRLHLPRPTKVXXXX 605
             A   D   Y C A N+ G+ +T A +Y               ++   + +P +V    
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 388

Query: 606 XXXXXXXXYLRHVER--ARP-------------YIPPGEEDRVYPPPQFIVPLKSVTAME 650
                    +   +   A+P             Y+   +   +   P F   L++++A E
Sbjct: 389 TTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASE 448

Query: 651 GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF-------TSIFRFGYI-SLDMLSLN 702
           G  + FE R++  G P+ K+EW + G  IE S  F        S+     I +L +  + 
Sbjct: 449 GQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEPEEICTLVIAEVF 506

Query: 703 IQDSGEYTCRAVSATGVAETKAVLHV 728
            + SG +TC A +  G   + A LHV
Sbjct: 507 AEGSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 76/311 (24%), Positives = 129/311 (41%), Gaps = 22/311 (7%)

Query: 3349 EENSGEYECVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKLQTLEDSMVR 3406
            ++N  E +      LG+  T ++++   +E  I  L+ +L   +E  LE+    E     
Sbjct: 873  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSLEQRLMNEIEFRLERTPVDESDDEI 932

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            + D  +   K  AP+F   L +   + EG    F  ++     P  KV W+ +GK +   
Sbjct: 933  QHD-EIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKR 988

Query: 3467 S---RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
            +   + R   D G   L I  T  +D G Y   A N  G    +  + VQ   ++ + S+
Sbjct: 989  NEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQ---SLPIRSR 1044

Query: 3524 LPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIP 3583
            L    +    +    E          P  E    P F   P D++  E      +C++  
Sbjct: 1045 LTSAGQSHRGRSRVQERDK------EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSG 1098

Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEAT 3642
            +    +   W  NG+P+L  +  K  + + G   L I  + QRDAG Y C ATN+ G+ +
Sbjct: 1099 LPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 1156

Query: 3643 VSCKLQVKGRQ 3653
             S +L V  ++
Sbjct: 1157 FSLELSVVAKE 1167



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 31/99 (31%), Positives = 53/99 (53%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP   + L+ + V EG  ++  C +VG P P V+WY   K ++ S    + +  + ++L 
Sbjct: 268  PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            I+EAF ED G Y C A N  G  + +A++ +     +D+
Sbjct: 328  IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDS 366



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 75/290 (25%), Positives = 116/290 (40%), Gaps = 46/290 (15%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            +E + Q P FT  ++   V E      +   I VG P  +V W   G  +E S  +  + 
Sbjct: 262  EEPLGQPPRFTQKLRSREVPEGTRVQLDC--IVVGIPPPQVRWYCEGKELENSPDIHIVQ 319

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ-HESALQKIQ 1822
                 +L +     ED+G Y+C A N  G   TS+ ++++  +S   E   ++  + +IQ
Sbjct: 320  AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQ 379

Query: 1823 Q-LEDSSRYQRREDVEVAVNQA------PRFIT--QLNGPTKLSEG-------------- 1859
            +  E SS       +  AV QA      PR  T  Q   PT   +G              
Sbjct: 380  KPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTK 439

Query: 1860 ----------QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS--------NDFGF 1901
                      Q   +ECR++  P P  +VEWY  G +++    +R S             
Sbjct: 440  MLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRISQKKPRSMAEPEEI 497

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
              L I  V+ E SG +TC A N  G   S  +L+V+  E +  +    SA
Sbjct: 498  CTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 547



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 72/256 (28%), Positives = 109/256 (42%), Gaps = 28/256 (10%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTLNDFG 3751
            P F   +K +  V EG PV F C++  VG P  ++ WF +G+  +  +   ++    D G
Sbjct: 945  PIFDKRLK-HFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGD-G 1000

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
              +L I+   + D G YT  A N  G      +I+CS    +V    +   ++       
Sbjct: 1001 TCSLHIESTTSDDDGNYTIMAANPQG------RISCSGHL-MVQSLPIRSRLTSAGQSHR 1053

Query: 3812 ERGRISDAPKEEPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
             R R+ +  KE P+      P F+         E    R +C+V     P+L   W  NG
Sbjct: 1054 GRSRVQERDKE-PLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNG 1110

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS-----CKK 3923
            + +LP       V + G  SL I  +   D+G Y C A N  G++     +S      KK
Sbjct: 1111 QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK 1170

Query: 3924 LPDII--LQN-QVPRG 3936
             P I+  LQN  VP G
Sbjct: 1171 APVILEKLQNCGVPEG 1186



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 36/98 (36%), Positives = 49/98 (50%), Gaps = 8/98 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--- 4467
            P+FTK +Q     E +   FE    G P P ++WYRE   I++SPDF+I     +S+   
Sbjct: 435  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEP 494

Query: 4468 -----LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
                 L+I +VF E S  F   A N+ GT    A L V
Sbjct: 495  EEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 70/266 (26%), Positives = 119/266 (44%), Gaps = 30/266 (11%)

Query: 1168 QIEEISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            Q +EI   K   P+F + L +   V+EG  +   C++  +G P  +V WF +G+ ++  +
Sbjct: 933  QHDEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRN 989

Query: 1225 ---RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE---RSDIVTD 1278
               + +   D G  +L I   TS D G YT+ A N  G    S  + V     RS + + 
Sbjct: 990  EHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSA 1048

Query: 1279 TQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVG 1338
             Q+ +   ++Q  +    + +  R        P F +A  ++   EG    L+C++   G
Sbjct: 1049 GQSHRGRSRVQERDKEPLQERFFR--------PHFLQAPGDMVAHEGRLCRLDCKVS--G 1098

Query: 1339 DQTMRVEWFCNGKPI--KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                 + W  NG+P+     H+     E    +L +  +   D+G Y C ATN+ G+   
Sbjct: 1099 LPPPELTWLLNGQPVLPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSF 1157

Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQ 1422
            S  L V+AK+      + P  LEK+Q
Sbjct: 1158 SLELSVVAKE----VKKAPVILEKLQ 1179



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 63/230 (27%), Positives = 95/230 (41%), Gaps = 15/230 (6%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI-KTGHRFRPAYEFDYV 1368
            AP F + L +    EG+ V   C++  VG    +V WF +GK I K     +   E D  
Sbjct: 944  APIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001

Query: 1369 -ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
             +L + S   +D G YT  A N  G    S  L V   + L + S+  S  +  +     
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQSHRGRSRV 1058

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
                K  + +     +P F+  P  +    EG+    +CK+  +    L   W  NGQPV
Sbjct: 1059 QERDKEPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 1113

Query: 1488 T--IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
                 H+   + + G  +L I  L   D+G Y C A N  G +  S  L+
Sbjct: 1114 LPDASHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELS 1162



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 61/237 (25%), Positives = 100/237 (42%), Gaps = 13/237 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694
            P F   LK     EG  + F  +I  VG P  K+ W K+G+ I   +    + R G    
Sbjct: 945  PIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTC 1002

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            SL + S    D G YT  A +  G       L V       R +   ++ +   ++++  
Sbjct: 1003 SLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERD 1062

Query: 755  KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT 814
            K    E ++E+   RP F++   D+    EGR    + +++ +  P +   W  +G+P+ 
Sbjct: 1063 K----EPLQERFF-RPHFLQAPGDM-VAHEGRLCRLDCKVSGLPPPELT--WLLNGQPVL 1114

Query: 815  A-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
              +S    +   G  SL I  L   DAG+Y   A NK G+   +  + V A+    A
Sbjct: 1115 PDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKA 1171



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 47/152 (30%), Positives = 73/152 (48%), Gaps = 12/152 (7%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS----RTAD 4676
            A P   + L++   +EGQ + F C++ G P P V+WY+   LI+ S  F++S    R+  
Sbjct: 433  AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMA 492

Query: 4677 E----YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN---LPALTPLRD 4729
            E     TL I+E F E  G + C A N  G V+  A+L V   +   N   L +     +
Sbjct: 493  EPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 552

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            +   E QP+   ++  S  +P    L EG L+
Sbjct: 553  LAAIEPQPSPPHSEPPSVEQPPKPKL-EGVLV 583



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 3/98 (3%)

Query: 3688 EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            E+    PPRFT +++   +VPEG  V  DC V  VG P  ++ W+  G+       +H +
Sbjct: 262  EEPLGQPPRFTQKLRSR-EVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIV 318

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                  +L I   +  D G Y+C A+N +G+ +T+A+I
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 62/244 (25%), Positives = 97/244 (39%), Gaps = 13/244 (5%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            LE+    ES +  +  EIP       P+F + L++   + EG    F C++  VG P  K
Sbjct: 920  LERTPVDESDDEIQHDEIPTGKCIA-PIFDKRLKHF-RVTEGSPVTFTCKI--VGIPVPK 975

Query: 2410 VEWFRNEKLIEDSSRITKTH--DFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            V WF++ K I   +   K      G  S+ I     +D+G Y   A+N  G         
Sbjct: 976  VYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 1035

Query: 2468 XXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAH 2527
                  + + ++     +  +   +  ER  E     F +P F Q   G     EG+   
Sbjct: 1036 VQS---LPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQA-PGDMVAHEGRLCR 1091

Query: 2528 YEARVVPVGDPSLRFEWYINGVE-LKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAI 2586
             + +V  +  P L   W +NG   L   S      + G  +L I+ +   DAG Y C A 
Sbjct: 1092 LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIAT 1149

Query: 2587 NRAG 2590
            N+ G
Sbjct: 1150 NKTG 1153



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 60/226 (26%), Positives = 102/226 (45%), Gaps = 19/226 (8%)

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS---RVKTINDFGFVILEIGGVYQR 3625
            ++E S   F C+++ +     +V WF +GK +   +   +++   D G   L I      
Sbjct: 956  VTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSD 1012

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEI 3685
            D G YT  A N  G  + S  L V   Q + +  +L S  +S      +    + +R++ 
Sbjct: 1013 DDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQS-----HRGRSRVQERDKE 1064

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP-FATGSRV 3744
             ++ E+   P F ++   ++   EG     DC+V   G P   + W  NG+P     S  
Sbjct: 1065 PLQ-ERFFRPHF-LQAPGDMVAHEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHK 1120

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              + + G  +L ID +  RDAG Y C ATNK G  + + +++  AK
Sbjct: 1121 MLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 1166



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 60/242 (24%), Positives = 103/242 (42%), Gaps = 17/242 (7%)

Query: 1571 DEVTTQ---APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            DE+ T    API    LK+  + EG    F  +++ +     KV W+ + K +   +   
Sbjct: 935  DEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIP--VPKVYWFKDGKQISKRNEHC 992

Query: 1628 ETNNFG--FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
            +    G    +L I S   +D G YT  A N  G    SG  +V   +S+ + S+   A 
Sbjct: 993  KMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAG 1049

Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
                      +  +   Q+      P F     D+   E +    + ++  +  P+L   
Sbjct: 1050 QSHRGRSRVQERDKEPLQERFF--RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL--T 1105

Query: 1746 WLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            WL NG P+  +AS+++  + + G  +L +  +   D+GTY C A N+ G+   S  L V 
Sbjct: 1106 WLLNGQPVLPDASHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVV 1164

Query: 1804 SK 1805
            +K
Sbjct: 1165 AK 1166



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 40/122 (32%), Positives = 57/122 (46%), Gaps = 8/122 (6%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTYT 4570
            PP FT   ++  V  G  V+LD  V G  P  V W   GK+++  PDI   I++    ++
Sbjct: 268  PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIH--IVQAGNLHS 325

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAEC----VVSLPATKDKPKPQTKAANAPPEII 4626
            L I EA+ +D+G+Y C A N  G     AE     V S  +  D  K +      P E+ 
Sbjct: 326  LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVS 385

Query: 4627 EP 4628
             P
Sbjct: 386  SP 387



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 9/145 (6%)

Query: 3146 GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG 3205
            GQ PRFT  +++ E + +G     +C VV +  P  ++ WY  G+ + +S  I  V    
Sbjct: 266  GQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQAGN 322

Query: 3206 FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELES 3265
               L IA     D+G Y C A N YG D T A I   G     + S   +      E+  
Sbjct: 323  LHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG-----VSSSDSEGDPNKEEMNR 377

Query: 3266 LQGAQQ-QTPSTPSAEPPKFITQIQ 3289
            +Q   +  +P T SA  P  + Q Q
Sbjct: 378  IQKPNEVSSPPTTSAVIPPAVPQAQ 402



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 49/164 (29%), Positives = 74/164 (45%), Gaps = 12/164 (7%)

Query: 2235 EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT 2294
            EEP   PPRF  +LR +  V EG     +C V  +  P +R  +Y  GK L+++   HI 
Sbjct: 262  EEPLGQPPRFTQKLR-SREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 2295 FDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  SL I     ED G YS  A N  G  T + S  +  +G   S+S+     E++ 
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYG--TDSTSAEIYIEGVSSSDSEGDPNKEEMN 376

Query: 2355 ELE-----SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQT 2393
             ++     S+ P     IP  V + + +  QP   +  IQ+ Q+
Sbjct: 377  RIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQP--RVATIQQCQS 418



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 6/159 (3%)

Query: 4343 QKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE 4402
            ++  +P P  +     EV+ A ++Q  K     +E  +  +     +    +       E
Sbjct: 207  ERSSVPIPIPADTRDNEVNHALEQQEAKR----REAEQAASEAAGGDTTPGSSPSSLYYE 262

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
             P+   +PP FT+K++   V E  + + +    G P P ++WY E   ++NSPD  I   
Sbjct: 263  EPL--GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQA 320

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
                 L I + F ED+  ++  A N  GT   SA + +E
Sbjct: 321  GNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 84/347 (24%), Positives = 129/347 (37%), Gaps = 50/347 (14%)

Query: 3413 EEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF 3472
            EE  G+ P FT  L + E + EG     +  +     P  +V WY  GK L+        
Sbjct: 262  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIV 318

Query: 3473 CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTI 3532
                   L I+  + ED+G Y C A N YG   T+A + ++G  +   E    K     I
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRI 378

Query: 3533 DK---IAALEGYSGTVDTLTPEAE------------------------SGNP----PEFT 3561
             K   +++    S  +    P+A+                         G P    P FT
Sbjct: 379  QKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFT 438

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG-----KPLLTGSRVK---TINDFG 3613
                +L  SE     FECR+      S +VEW+  G      P    S+ K         
Sbjct: 439  KMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEPEE 496

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ 3673
               L I  V+   +G +TC A+N++G  +   +L V+G + +     L  H  + T ++ 
Sbjct: 497  ICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSL--HSANSTTNLA 554

Query: 3674 KLE-ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPE---GGPVHFD 3716
             +E +      E    ++ P P    V +  N        G  VHFD
Sbjct: 555  AIEPQPSPPHSEPPSVEQPPKPKLEGVLVNHNEPRSSSRIGLRVHFD 601



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 36/135 (26%), Positives = 60/135 (44%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+  QK R+ ++ EG   Q    + G P P+V W+  G+ L NS    I+   N  +L 
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +    + D+G Y+  A N  G   TS  + +E  + S  +   ++   +  Q+  E    
Sbjct: 328 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSP 387

Query: 385 ISEKALAPQFVKVCQ 399
            +  A+ P  V   Q
Sbjct: 388 PTTSAVIPPAVPQAQ 402



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
            EEP+   PP+F  +++S  V E   V+ +C V     P++R  WY  GK L +      V
Sbjct: 262  EEPL-GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
                  SL I   + ED+G Y C A N +G D T A I
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 15/222 (6%)

Query: 3985 LVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY--DFGYVAMNFGWVYPED 4042
            + E     F C++  VG P  KV WF +GK +  +N    +     G  +++      +D
Sbjct: 956  VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDD 1013

Query: 4043 SGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             G Y   A N  G       +     P       +   + S  +     +  Q   ++ +
Sbjct: 1014 DGNYTIMAANPQGRISCSGHLMVQSLP-------IRSRLTSAGQSHRGRSRVQERDKEPL 1066

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY- 4161
            +E   R  P F+  P  +   EG   R  C+V+G P P + WLLNG  ++  + +K+   
Sbjct: 1067 QERFFR--PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVR 1124

Query: 4162 -DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
              G++   I    Q D G  + I             L V+ +
Sbjct: 1125 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 1166



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 7/105 (6%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F K+ Q+   +EG++  F+CRV G P P+V W+     I D  + +I   +  + A 
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAE 493

Query: 450 ------LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
                 L+I  V    SG  TC A NK G  +   +L+V   E +
Sbjct: 494 PEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            + P+F + +++ EV EG  V L+  +  +  P +R  WYC G+ ++              
Sbjct: 267  QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIVQAGNLH 324

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD-TLDEQRLKKIQELEKY 2094
            +L I  A+ EDTG Y C A+N  G   T++ + ++  S    +   +++ + +IQ+  + 
Sbjct: 325  SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEV 384

Query: 2095 ERP 2097
              P
Sbjct: 385  SSP 387



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 68/275 (24%), Positives = 113/275 (41%), Gaps = 26/275 (9%)

Query: 751  EDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG 810
            E   + QH E I       P F + L+    + EG    F  ++  +  P  +V W+KDG
Sbjct: 927  ESDDEIQHDE-IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGI--PVPKVYWFKDG 982

Query: 811  RPITASSRITSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
            + I+  +    +   G    SL+I    ++D G+YT+ A N  G    +  + V +    
Sbjct: 983  KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---- 1038

Query: 869  TADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
                 +P + R +                    + E   +P F     D ++  EG    
Sbjct: 1039 -----LPIRSR-LTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVA-HEGRLCR 1091

Query: 929  FEARLEPIGDSTLRVEWLKDGRPV--EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
             + ++  +    L   WL +G+PV  +AS ++      G  +L I  +T  DAG Y C A
Sbjct: 1092 LDCKVSGLPPPELT--WLLNGQPVLPDASHKMLVR-ETGVHSLLIDPLTQRDAGTYKCIA 1148

Query: 987  YNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             N  GQ + S  L++V K+      + P  LEK+Q
Sbjct: 1149 TNKTGQNSFSLELSVVAKE----VKKAPVILEKLQ 1179



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 59/237 (24%), Positives = 95/237 (40%), Gaps = 19/237 (8%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVS 2832
            +F   L +    EG  + F C +     P  K+ WF + K +     +           S
Sbjct: 946  IFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 1003

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE 2892
            L I  T  +D G YT  A N +G  + SG L            Q    ++ L +  Q+  
Sbjct: 1004 LHIESTTSDDDGNYTIMAANPQGRISCSGHLM----------VQSLPIRSRLTSAGQSHR 1053

Query: 2893 ARLAKGRRPSVPDTE-YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNG 2951
             R     R   P  E + +P + +    +    EG++  L+ +V     P+L   W  NG
Sbjct: 1054 GRSRVQERDKEPLQERFFRPHF-LQAPGDMVAHEGRLCRLDCKVSGLPPPEL--TWLLNG 1110

Query: 2952 K-VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
            + VL   S   L  + G  +L +  + +RD+G Y C A NK G+   S  +   +K+
Sbjct: 1111 QPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P+F++ L + E  EGT V L+C +  VG    +V W+C GK ++           +  
Sbjct: 267  QPPRFTQKLRSREVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQAGNLH 324

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L +   + ED+G Y+C A+N  G   TS  + +
Sbjct: 325  SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 7/161 (4%)

Query: 3965 YDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTP 4024
            Y+    QPPRF  +++S+      E T+ +     VG P  +V W+  GK L +      
Sbjct: 261  YEEPLGQPPRFTQKLRSREV---PEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI 317

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSI 4084
            +      ++     + ED+G Y C A+N+YG D T A I   G      DS+   + + +
Sbjct: 318  VQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEM 375

Query: 4085 EKIRE-MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEE 4124
             +I++  E S   T   V+  +  +   + V+ P   T+++
Sbjct: 376  NRIQKPNEVSSPPTTSAVIPPAVPQAQHL-VAQPRVATIQQ 415



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 23/238 (9%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM---RHSTRIKTVSDFG 3205
            P F   +++   + +G    F C +V +  P  K+ W+ +G+ +       +++   D G
Sbjct: 945  PIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCKMRREGD-G 1000

Query: 3206 FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDS-LAKIRELE 3264
               L I  T + D G Y   A N  G       I+C   G + ++SL   S L    +  
Sbjct: 1001 TCSLHIESTTSDDDGNYTIMAANPQGR------ISC--SGHLMVQSLPIRSRLTSAGQSH 1052

Query: 3265 SLQGAQQQTPSTPSAEP---PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321
              +   Q+    P  E    P F+    D+    EG+    + ++  +  P+L   W  N
Sbjct: 1053 RGRSRVQERDKEPLQERFFRPHFLQAPGDMVAH-EGRLCRLDCKVSGLPPPELT--WLLN 1109

Query: 3322 GKK-LPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            G+  LP         + G+  L I    + ++G Y+C+ATNK G++S    L   +KE
Sbjct: 1110 GQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 57/214 (26%), Positives = 98/214 (45%), Gaps = 25/214 (11%)

Query: 1077 VEWYFNGKQITSAN---RIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            V W+ +GKQI+  N   +++   D G  +L I S  ++D G YT++A N  G    S  +
Sbjct: 976  VYWFKDGKQISKRNEHCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 1034

Query: 1134 TVET---RSSIDTS-SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPV 1189
             V++   RS + ++   HRG   ++R  E  K  EP+ +       +P F+Q        
Sbjct: 1035 MVQSLPIRSRLTSAGQSHRG---RSRVQERDK--EPLQE----RFFRPHFLQ-APGDMVA 1084

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGFVALDIIHATSADTG 1248
             EG+   L+C++   G P   + W  NG+ V   +  K    + G  +L I   T  D G
Sbjct: 1085 HEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAG 1142

Query: 1249 EYTVRAVNHLG----SAHTSAIVRVIERSDIVTD 1278
             Y   A N  G    S   S + + ++++ ++ +
Sbjct: 1143 TYKCIATNKTGQNSFSLELSVVAKEVKKAPVILE 1176



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 27/85 (31%), Positives = 42/85 (49%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            LR   V EG   Q    +     P ++W  EG  +  +PD  ++  GN   L I   +EE
Sbjct: 275  LRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEE 334

Query: 4787 DTGTFTCRATTAAGQVETSAKLVVK 4811
            DTG ++C A+   G   TSA++ ++
Sbjct: 335  DTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 34/221 (15%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT--THNHTTL 323
            P   Q P +    EG   +   ++SG P P +TW  NGQ ++    H+++   T  H+ L
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                TQ+ D+G Y         CI T+                     T       E  +
Sbjct: 1133 IDPLTQR-DAGTYK--------CIATNK--------------------TGQNSFSLELSV 1163

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
               E   AP  ++  Q+  V EG   R +CRV G P P V ++  D +       +I ++
Sbjct: 1164 VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMP-PPVFYWKKDNETIPCTRERISMH 1222

Query: 444  E--SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            +  +G   L+I     SD+G  T  A+N++G  +   RL++
Sbjct: 1223 QDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 33/112 (29%), Positives = 49/112 (43%)

Query: 50   TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
            T V+ S D         G+   PIF++  K+ R  +G    F  K+ G P P V W +  
Sbjct: 923  TPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDG 982

Query: 110  APLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              + + N++     E  G  SL I+     D+G YT  A N  G   CS ++
Sbjct: 983  KQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 1034



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 8/103 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
           K  + AP F +    L+  EG+ VV   R  G P+P++ W ++G  I  +P+ RI     
Sbjct: 429 KPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKP 488

Query: 545 AS--------TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            S        TL I    A  +  + CTA N  G+ ++ A+L+
Sbjct: 489 RSMAEPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLH 531



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 8/93 (8%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ--------MIHEGNNAVL 4778
            L+++   EGQ   F+ ++     P ++W REG LI ++PDF+        M        L
Sbjct: 441  LQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEPEEICTL 500

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +I   + E +G FTC A+   G V + A+L V+
Sbjct: 501  VIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVR 533



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 104/250 (41%), Gaps = 22/250 (8%)

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276
            LE+    E+       E+   K   P F   L+    V EG    F C++  +  P  ++
Sbjct: 920  LERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KV 976

Query: 2277 EFYHNGKALQSAARFHITF---DFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAIS 2331
             ++ +GK + S    H        G  SL I+    +D G Y++ A N  G   C+  + 
Sbjct: 977  YWFKDGKQI-SKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 1035

Query: 2332 M-TVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390
            + ++  +  + S  Q   G  +++E +  EP +           RP F Q   ++    E
Sbjct: 1036 VQSLPIRSRLTSAGQSHRGRSRVQERDK-EPLQERFF-------RPHFLQAPGDMV-AHE 1086

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            G+    DC++   G P  ++ W  N + ++ D+S      + G  S+ I  +   D G Y
Sbjct: 1087 GRLCRLDCKVS--GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTY 1144

Query: 2450 MCRASNLLGE 2459
             C A+N  G+
Sbjct: 1145 KCIATNKTGQ 1154



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 57/231 (24%), Positives = 89/231 (38%), Gaps = 13/231 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG---AR 2690
            + TG   APIF   LK + ++ EG  V    ++     P  K+ WFK+G  ++      +
Sbjct: 937  IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEHCK 993

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            ++   D G  +L I S  +DD G YT  A N  G    +  + ++     +   L     
Sbjct: 994  MRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSAGQ 1050

Query: 2751 DRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWF 2810
               G                     F+    ++V  EG     +C V  S  P  ++ W 
Sbjct: 1051 SHRGR-SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV--SGLPPPELTWL 1107

Query: 2811 FNNKP-LPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
             N +P LP  +      +    SL I    + D+G Y C ATN  G  + S
Sbjct: 1108 LNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFS 1158



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 11/91 (12%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKTHDFGY 2433
            PVFT+ LQN+ +  EGQ   F+CR+   G P+ KVEW+R   LIEDS   RI++      
Sbjct: 435  PVFTKMLQNL-SASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRISQKKPRSM 491

Query: 2434 V------SMTISHVRDEDEGVYMCRASNLLG 2458
                   ++ I+ V  E  G + C ASN  G
Sbjct: 492  AEPEEICTLVIAEVFAEGSGCFTCTASNKYG 522



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 4/117 (3%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            Q P FTQ L++ + + EG     DC  I VG P  +V W+   K +E+S  I        
Sbjct: 267  QPPRFTQKLRSRE-VPEGTRVQLDC--IVVGIPPPQVRWYCEGKELENSPDIHIVQAGNL 323

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE-TQHPEGMKKIQK 2489
             S+TI+   +ED G Y C ASN+ G                  E   + E M +IQK
Sbjct: 324  HSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQK 380



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 10/110 (9%)

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR------ 1360
            ++ AP F++ L N+   EG  V  ECR++  G  + +VEW+  G  I+    FR      
Sbjct: 431  IIAAPVFTKMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRISQKKP 488

Query: 1361 --PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
               A   +   L +  V+ E SG +TC A+N+ G   +   L V   +DL
Sbjct: 489  RSMAEPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P  +PP+F  +++   ++ EG     +  +V +  P  +V W+  GK+L +         
Sbjct: 264  PLGQPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQA 320

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              +  L I   +EE++G Y C A+N  G DST A +
Sbjct: 321  GNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 3/82 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HAL 450
           P+F +  + R+V EG   + DC V G P P+V W+   +++ +  +  I + ++GN H+L
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELEN--SPDIHIVQAGNLHSL 326

Query: 451 MITNVTLSDSGVVTCVARNKSG 472
            I      D+G  +C A N  G
Sbjct: 327 TIAEAFEEDTGRYSCFASNIYG 348



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 44/151 (29%), Positives = 68/151 (45%), Gaps = 14/151 (9%)

Query: 1678 ESQHEGALPR---LNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARL 1734
            ++QH  A PR   + Q +  + Y +     + I  APVFT  ++++  +E Q   FE R+
Sbjct: 400  QAQHLVAQPRVATIQQCQSPTNYLQ-GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRV 458

Query: 1735 IPVGDPKLRVEWLRNGVPIEAS-------NRLTTMHDFGYV-ALNMKYVNPEDSGTYTCR 1786
               G P  +VEW R G  IE S        +  +M +   +  L +  V  E SG +TC 
Sbjct: 459  --KGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEPEEICTLVIAEVFAEGSGCFTCT 516

Query: 1787 AINELGEAVTSSTLFVQSKASLQLESQHESA 1817
            A N+ G   + + L V+    L       SA
Sbjct: 517  ASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 547



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 12/145 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLNDFGF 3752
            P FT ++  N+   EG  V F+CRV+  G P+ +++W+  G         R+        
Sbjct: 435  PVFT-KMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRISQKKPRSM 491

Query: 3753 I------ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
                    L I  ++A  +G +TC A+NK+G+ ++ A++      D+     L    S  
Sbjct: 492  AEPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTT 551

Query: 3807 KIKELERGRISDAPKEEPIVSTPPK 3831
             +  +E  + S    E P V  PPK
Sbjct: 552  NLAAIE-PQPSPPHSEPPSVEQPPK 575



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 5/123 (4%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            E  + Q PRF  +L    ++ EG     +C +   P P +R  WY  GK L++       
Sbjct: 262  EEPLGQPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
                  +L I   + ED+G Y+C A N  G   +S  + ++   S   DS+ +   E++ 
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMN 376

Query: 1957 YLE 1959
             ++
Sbjct: 377  RIQ 379



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 8/95 (8%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIR----- 4559
            G+  I  P FT   QN++ + GQLV  + +V G     V W + G  ++  PD R     
Sbjct: 428  GKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKK 487

Query: 4560 -NKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
               + E +   TL+I E + + SG + C A N  G
Sbjct: 488  PRSMAEPEEICTLVIAEVFAEGSGCFTCTASNKYG 522



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 74/303 (24%), Positives = 115/303 (37%), Gaps = 47/303 (15%)

Query: 2870 NIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYP--KPEWIIPIAAEHQLVEGQ 2927
            N   + Q  + +   +A  +A       G  PS    E P  +P          ++ EG 
Sbjct: 225  NHALEQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGT 284

Query: 2928 VLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCK 2987
             + L+  V     P  ++ WY  GK LE      +       +L + + +E D+G Y+C 
Sbjct: 285  RVQLDCIVV--GIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCF 342

Query: 2988 AYNKRGEAFTSSTVY---CTSKDN-------LIERTQHPKGTE-----------GLEKIQ 3026
            A N  G   TS+ +Y    +S D+        + R Q P                + + Q
Sbjct: 343  ASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQ 402

Query: 3027 NLEDSLRKEPGQQPDDDT-------GRP----PEFTTVFKDIVDISEGQIAHYEASLIPT 3075
            +L    R    QQ    T       G+P    P FT + +++   SEGQ+  +E  +   
Sbjct: 403  HLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNL-SASEGQLVVFECRV--K 459

Query: 3076 GDQSMVIEWFYNGKTIEAS--HRIRTVYAFGMV------VLEILGTKTTDSGTYSCRATN 3127
            G  S  +EW+  G  IE S   RI       M        L I       SG ++C A+N
Sbjct: 460  GAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEPEEICTLVIAEVFAEGSGCFTCTASN 519

Query: 3128 KWG 3130
            K+G
Sbjct: 520  KYG 522



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 11/97 (11%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR--- 3879
            +PI++ P  F   +++ +  E + V FECRV+    PK  +EWYR G L+     +R   
Sbjct: 429  KPIIAAPV-FTKMLQNLSASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRISQ 485

Query: 3880 -----TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                         +L I  V+AE SG + C A N +G
Sbjct: 486  KKPRSMAEPEEICTLVIAEVFAEGSGCFTCTASNKYG 522



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+V +EG+  +   +++    P + WL  G  ++P+     ++ E     LLI    + D
Sbjct: 1081 DMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRD 1140

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             GT+ C AT   GQ   S +L V +K
Sbjct: 1141 AGTYKCIATNKTGQNSFSLELSVVAK 1166



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 27/98 (27%), Positives = 52/98 (53%), Gaps = 8/98 (8%)

Query: 64  GRPGEP--SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR-----KKAPLVECN 116
           G  G+P  + P+F ++ +N   ++G    FE +++G P+P V W R     + +P    +
Sbjct: 425 GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRIS 484

Query: 117 KYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYG 153
           +   R   +  ++ +L+I ++     G +TCTA N+YG
Sbjct: 485 QKKPRSMAEPEEICTLVIAEVFAEGSGCFTCTASNKYG 522



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 8/108 (7%)

Query: 3036 PGQQP-----DDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090
            PG  P     ++  G+PP FT   +   ++ EG     +   I  G     + W+  GK 
Sbjct: 252  PGSSPSSLYYEEPLGQPPRFTQKLRSR-EVPEG--TRVQLDCIVVGIPPPQVRWYCEGKE 308

Query: 3091 IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            +E S  I  V A  +  L I      D+G YSC A+N +G    S ++
Sbjct: 309  LENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 40/142 (28%), Positives = 59/142 (41%), Gaps = 21/142 (14%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG--- 2165
            PVF   L +L +  EG    FECRV+    P   ++W+  G  I     +R +       
Sbjct: 435  PVFTKMLQNL-SASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRISQKKPRSM 491

Query: 2166 -----YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKI 2220
                    L I   +AE SG + C A+NK G   +   L V G+ ++       NG    
Sbjct: 492  AEPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDL-----SNNG---- 542

Query: 2221 RQLEAQGHSTRIEVEEPKISPP 2242
              L +   +T +   EP+ SPP
Sbjct: 543  -SLHSANSTTNLAAIEPQPSPP 563



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 63/232 (27%), Positives = 90/232 (38%), Gaps = 17/232 (7%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH-- 1491
            D I     I P F  R K    V EG  V F CK+  +     KV WFK+G+ ++  +  
Sbjct: 935  DEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNEH 991

Query: 1492 -RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             + R   D G  +L I    ++D G YT  A N  G    S  L  +S    +RS    A
Sbjct: 992  CKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSA 1048

Query: 1551 GLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL 1609
            G    Q    RS+    D    +     P    +  ++   EG+    + ++  +    L
Sbjct: 1049 G----QSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL 1104

Query: 1610 KVEWYHNNKP-LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
               W  N +P L   S        G  +L I      D+GTY C A N  G+
Sbjct: 1105 --TWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ 1154



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 45/143 (31%), Positives = 58/143 (40%), Gaps = 18/143 (12%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST--RIKTVSDFGF 3206
            P FT  +QN+    +GQ   FEC V     P  K+EWY  G  +  S   RI        
Sbjct: 435  PVFTKMLQNLSA-SEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRISQKKPRSM 491

Query: 3207 V------VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD-SLAK 3259
                    L IA      SG + C A NKYG   + A ++  G      E L  + SL  
Sbjct: 492  AEPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGN-----EDLSNNGSLHS 546

Query: 3260 IRELESLQGAQQQTPSTPSAEPP 3282
                 +L   + Q PS P +EPP
Sbjct: 547  ANSTTNLAAIEPQ-PSPPHSEPP 568



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 7/160 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L +    EG  +  +C V     P  ++ W+   K L +          +  SL I
Sbjct: 271  FTQKLRSREVPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQAGNLHSLTI 328

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               +EED+G Y+C A+N  G+ +TS  +   G  +   D++    K  +  +++  E   
Sbjct: 329  AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMNRIQKPNEVSS 386

Query: 2896 AKGRRPSVPDTEYPKPEWII--PIAAEHQLVEGQVLHLEG 2933
                   +P    P+ + ++  P  A  Q  +    +L+G
Sbjct: 387  PPTTSAVIPPA-VPQAQHLVAQPRVATIQQCQSPTNYLQG 425



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 10/105 (9%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF------ 2828
            VF   L N+   EG  + FEC V+ +  P  K+EW+     +     ++ +         
Sbjct: 436  VFTKMLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRISQKKPRSMAE 493

Query: 2829 --SYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
                 +L I   + E SG +TC A+N  G+ ++   L   G++++
Sbjct: 494  PEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGD 128
            +P I E++ +N    +G   + E ++ G P PV  W +K    + C +  +  + + TG 
Sbjct: 1171 APVILEKL-QNCGVPEGHPVRLECRVIGMPPPVFYW-KKDNETIPCTRERISMHQDTTGY 1228

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
              LLI+     D G YT +A+N+ G   C+
Sbjct: 1229 ACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 2097 PKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            P  +  E+P GQ P F   L S E + EG R   +C V  I  P   + W+  G+++   
Sbjct: 256  PSSLYYEEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPPQ--VRWYCEGKELENS 312

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                        +L I   + ED+G Y C A+N  G    +  + + G
Sbjct: 313  PDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG 360



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 630 EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
           E+ +  PP+F   L+S    EG ++  +  +  VG P  ++ W   G+ +E S     + 
Sbjct: 262 EEPLGQPPRFTQKLRSREVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQ 319

Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
                SL +     +D+G Y+C A +  G   T A +++
Sbjct: 320 AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            +E +   PRF  + +S E V EG  V  +C +  +     +V W+  G+ +        +
Sbjct: 262  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIV 318

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                  +L I +   ED+G Y+C A N+ GTD  S  +
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 356



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF-ATGS 3742
            E+++  ++       +E   N  VPEG PV  +CRV  +G P     W  +      T  
Sbjct: 1160 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV--IGMPPPVFYWKKDNETIPCTRE 1217

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            R+    D  G+  L I      DAG YT  A N+ G  + TA++   A+
Sbjct: 1218 RISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 1266



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLT--------SDFGFVTLDLVDV 2976
            EGQ++  E +V  K  P  K+EWY  G ++E    F+++              TL + +V
Sbjct: 448  EGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEPEEICTLVIAEV 505

Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL 3009
            +   SG +TC A NK G   + + ++    ++L
Sbjct: 506  FAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDL 538



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 4/140 (2%)

Query: 1571 DEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +E   Q P  T  L++ E+ EG R   +   I V     +V WY   K L++        
Sbjct: 262  EEPLGQPPRFTQKLRSREVPEGTRVQLD--CIVVGIPPPQVRWYCEGKELENSPDIHIVQ 319

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQ 1690
                 +L I     ED+G Y+C A N  G   TS    +    S   +S+ +     +N+
Sbjct: 320  AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMNR 377

Query: 1691 LEDTSKYQRHSAQDEVITQA 1710
            ++  ++         VI  A
Sbjct: 378  IQKPNEVSSPPTTSAVIPPA 397



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 6/122 (4%)

Query: 1170 EEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            EE     P F Q L +   V EG  + L+C +  +G P  +V W+  G+ +         
Sbjct: 262  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIV 318

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV--IERSDIVTDTQNEQAIEQ 1287
                  +L I  A   DTG Y+  A N  G+  TSA + +  +  SD   D  N++ + +
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD-PNKEEMNR 377

Query: 1288 IQ 1289
            IQ
Sbjct: 378  IQ 379



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 2632 MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691
            ++ +  + Q P FT  L+S + + EG  V L+  V     P  ++ W+  G  L     +
Sbjct: 259  LYYEEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDI 315

Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
                   L +L+I     +D+G Y+C A+N+ G   ++A I IE
Sbjct: 316  HIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 11/132 (8%)

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
            +A I++ +S     Q     P    P F   +Q+++   EGQ   FE R+     P  KV
Sbjct: 410  VATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSAS-EGQLVVFECRVKGAPSP--KV 466

Query: 3317 EWFYNGKKLPHGHRYRTFHDFG--------IVILDILYCYEENSGEYECVATNKLGRDST 3368
            EW+  G  +     +R              I  L I   + E SG + C A+NK G  S+
Sbjct: 467  EWYREGTLIEDSPDFRISQKKPRSMAEPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSS 526

Query: 3369 KANLKCTSKENL 3380
             A L     E+L
Sbjct: 527  IAQLHVRGNEDL 538



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E  + Q PRF   L+ + ++ EG     +  V         V WY  GK++ ++  I   
Sbjct: 262  EEPLGQPPRFTQKLR-SREVPEGTRVQLDCIVVGIPP--PQVRWYCEGKELENSPDIHIV 318

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
                  +L IA    ED+G Y+  A N  G    SA + +E  SS D+
Sbjct: 319  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDS 366



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 6/123 (4%)

Query: 763 EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822
           EE   Q P+F + L+   E+ EG     +  +  +  P +R  WY +G+ +  S  I  +
Sbjct: 262 EEPLGQPPRFTQKLRSR-EVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 318

Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP--EQRRY 880
                 SL I     ED G Y+  A N  G   ++A I +   S+  ++ G P  E+   
Sbjct: 319 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSE-GDPNKEEMNR 377

Query: 881 IEK 883
           I+K
Sbjct: 378 IQK 380



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            + ++  + P  +  LQ+ G + EG     E ++  +  P     W KD   I  +    S
Sbjct: 1164 VAKEVKKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERIS 1220

Query: 822  IFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            +     GY  L I   +  DAG YT+ A N+ G    TA + + A+
Sbjct: 1221 MHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 1266



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G   + + K+ G P P ++W     P++    + M   E TG  SLLI  +   D G Y
Sbjct: 1086 EGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRE-TGVHSLLIDPLTQRDAGTY 1144

Query: 145  TCTARNQYGE 154
             C A N+ G+
Sbjct: 1145 KCIATNKTGQ 1154



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 16/50 (32%), Positives = 26/50 (52%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            PVF  +   ++  EG+   F CRV G P P+V W   G  I +   ++++
Sbjct: 435  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRIS 484



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 12/115 (10%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA--RLKSTFDFG 2698
            AP+FT  L++     EGQ V  E +V+    P  K+EW++ G  +      R+       
Sbjct: 434  APVFTKMLQNLSAS-EGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRISQKKPRS 490

Query: 2699 LV------TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE-SLH 2746
            +       TL I  +  + SG +TC A+N  G   S A + +     L    SLH
Sbjct: 491  MAEPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLH 545



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 4/88 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-- 1764
            + +APV    +++  V E      E R+I  G P     W ++   I  +    +MH   
Sbjct: 1168 VKKAPVILEKLQNCGVPEGHPVRLECRVI--GMPPPVFYWKKDNETIPCTRERISMHQDT 1225

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELG 1792
             GY  L ++     D+G YT  A NE G
Sbjct: 1226 TGYACLLIQPAKKSDAGWYTLSAKNEAG 1253



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 1/84 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            +P  +  E     PP F     +  V EG   +  C V G P P+V W   G  + N   
Sbjct: 255  SPSSLYYEEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPD 314

Query: 4157 YKLTYDGMYH-FDIPKTRQYDTGK 4179
              +   G  H   I +  + DTG+
Sbjct: 315  IHIVQAGNLHSLTIAEAFEEDTGR 338



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 11/91 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTT------- 2560
            P+FT++L   S   EGQ   +E RV   G PS + EWY  G  ++    FR +       
Sbjct: 435  PVFTKMLQNLSAS-EGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRISQKKPRSM 491

Query: 2561 -HDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   TL I  V A  +G + C A N+ G
Sbjct: 492  AEPEEICTLVIAEVFAEGSGCFTCTASNKYG 522



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT-VGSRFKTYYDF 1232
            K  PV ++ L N   V EG  + LECR+  M  P     W  +  ++     R   + D 
Sbjct: 1169 KKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERISMHQDT 1225

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             G+  L I  A  +D G YT+ A N  G    +A
Sbjct: 1226 TGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTA 1259



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 3/95 (3%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            Q P F   ++ +  + EG     +  +  +G    +V W  +G+ +E S  I        
Sbjct: 267  QPPRFTQKLRSR-EVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQAGNL 323

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +LTI      D G Y+C A N  G  +TSA + I
Sbjct: 324  HSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/102 (30%), Positives = 41/102 (40%), Gaps = 12/102 (11%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--------TE 1628
            AP+ T  L+N+   EGQ   FE R+      + KVEWY     ++    F        + 
Sbjct: 434  APVFTKMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRISQKKPRSM 491

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
                    L I     E SG +TC A N  G    S IA +H
Sbjct: 492  AEPEEICTLVIAEVFAEGSGCFTCTASNKYG--TVSSIAQLH 531



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 37/164 (22%), Positives = 59/164 (35%), Gaps = 11/164 (6%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY---KLTYDGMYHF 4167
            P+F        V EG    F C++ G P P+V W  +G  I   + +   +   DG    
Sbjct: 945  PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRT 4227
             I  T   D G   ++             L V  +    R  L +A +     +   +R 
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV--QSLPIRSRLTSAGQSHRGRSRVQERD 1062

Query: 4228 ETELEKTFEERQVLQRQG-VIDH-----RPELKPKVIKEPETEW 4265
            +  L++ F     LQ  G ++ H     R + K   +  PE  W
Sbjct: 1063 KEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTW 1106



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            + P FTQ L    E+ EG     +  VV +  P +R  WY  G EL+             
Sbjct: 267  QPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIVQAGNL 323

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I      D G Y C A N  G
Sbjct: 324  HSLTIAEAFEEDTGRYSCFASNIYG 348



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129
           PP F Q  ++    +G   + +  + G P P V W  +   L       +    Q G++ 
Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI---VQAGNLH 324

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           SL I +    D G Y+C A N YG    S  I  EG
Sbjct: 325 SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG 360



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 11/101 (10%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASS--RIT-----SI 822
           P F + LQ+L    EG+   FE ++     P  +VEWY++G  I  S   RI+     S+
Sbjct: 435 PVFTKMLQNLSA-SEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRISQKKPRSM 491

Query: 823 FNFGYV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                + +L I  + AE +G +T  A NK G   S A + V
Sbjct: 492 AEPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHV 532


>AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein
            protein.
          Length = 1391

 Score =  222 bits (542), Expect = 3e-56
 Identities = 123/364 (33%), Positives = 198/364 (54%), Gaps = 9/364 (2%)

Query: 220  DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQE 279
            ++K+ +FE RL+ E+ FR  + +  V ESD +I  + +   G    P   ++ ++ ++ E
Sbjct: 973  EYKISSFEQRLMNEIEFR--LERTPVDESDDEIQHD-EIPTGKCIAPIFDKRLKHFRVTE 1029

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT--LRVRNTQKSDSGHYT 337
            G+   F  ++ G P P+V WFK+G+++   N+   +      T  L + +T   D G+YT
Sbjct: 1030 GSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSLHIESTTSDDDGNYT 1089

Query: 338  LLAENPNGCIVTSGYLAVES-PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            ++A NP G I  SG+L V+S P  S +      +   ++ +E ++   + E+   P F++
Sbjct: 1090 IMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKE-PLQERFFRPHFLQ 1148

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
               D    EG++ R DC+V+G P PE+TW +N + +  D  HK+LV E+G H+L+I  +T
Sbjct: 1149 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLT 1208

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
              D+G   C+A NK+G+ +F   L+V+ KE   AP  +E+     V EG PV L  R +G
Sbjct: 1209 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIG 1268

Query: 517  TPTPRITWQKDGVPI-IPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
             P P   W+KD   I      + +H D  G + L I  AK SDA WY  +A+N AG  + 
Sbjct: 1269 MPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSC 1328

Query: 575  RARL 578
             ARL
Sbjct: 1329 TARL 1332



 Score =  112 bits (269), Expect = 3e-23
 Identities = 84/322 (26%), Positives = 134/322 (41%), Gaps = 22/322 (6%)

Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP-DIRNKILEE-D 4566
            G  + P F    ++  VT G  V    K+ G     VYW K+GK++   + R K+  E D
Sbjct: 1011 GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGD 1070

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV-SLPA----------------TK 4609
            GT +L I      D G Y  +A N  G   C    +V SLP                  +
Sbjct: 1071 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1130

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKY 4668
            ++ K   +     P  ++   D +  EG+     CK+ G P P + W   G  ++  + +
Sbjct: 1131 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPH 1190

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              + R    ++L I      D G YKC+A N  G+ + + +L V   +       L  L+
Sbjct: 1191 KMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQ 1250

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN--AVLLIGNTYEE 4786
            +  V EG P + + ++     P   W ++   IP T +   +H+     A LLI    + 
Sbjct: 1251 NCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKS 1310

Query: 4787 DTGTFTCRATTAAGQVETSAKL 4808
            D G +T  A   AG V  +A+L
Sbjct: 1311 DAGWYTLSAKNEAGIVSCTARL 1332



 Score =  109 bits (261), Expect = 3e-22
 Identities = 106/418 (25%), Positives = 170/418 (40%), Gaps = 55/418 (13%)

Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI 4382
            +DN+ +T+    + + KK+T     P+  E  +   E  +  + + + E        R  
Sbjct: 944  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLE--------RTP 995

Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
                  EI+H         E P      PIF K+++  RV E     F  +  G P+P +
Sbjct: 996  VDESDDEIQHD--------EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKV 1047

Query: 4443 KWYRENFPI--KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             W+++   I  +N              L I     +D   +  +A N  G   CS +L+V
Sbjct: 1048 YWFKDGKQISKRNERCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1107

Query: 4501 EE-----------KRRQGRGGIVP------------PSFTLTAQNVNVTSGQLVRLDTKV 4537
            +            +  +GR  +              P F     ++    G+L RLD KV
Sbjct: 1108 QSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV 1167

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKIL-EEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            +G  P ++ WL NG+ V PD  +K+L  E G ++LLI     +D+G Y+C+A N  G+  
Sbjct: 1168 SGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNS 1227

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               E  V             K     P I+E L++  V EG  +   C+++G P P   W
Sbjct: 1228 FSLELSV-----------VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYW 1276

Query: 4657 YKGDKLIKPSK-YFQMSRTADEYT-LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             K ++ I  ++    M +    Y  L I  A   D G Y   A N AG V+  A+L +
Sbjct: 1277 KKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1334



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 67/234 (28%), Positives = 98/234 (41%), Gaps = 13/234 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGY 1767
            AP+F   +K  RV E     F  +++ +  PK  V W ++G  I   N    M     G 
Sbjct: 1015 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPK--VYWFKDGKQISKRNERCKMRREGDGT 1072

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+++    +D G YT  A N  G    S  L VQS   L + S+  SA Q  +     
Sbjct: 1073 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---LPIRSRLTSAGQSHR---GR 1126

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-V 1886
            SR Q R+   +          Q  G     EG+    +C++   P P +   W  NG+ V
Sbjct: 1127 SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 1184

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            L          + G  +L I  +   D+G Y C A N  GQ   S+ L+V +KE
Sbjct: 1185 LPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1238



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 64/266 (24%), Positives = 111/266 (41%), Gaps = 30/266 (11%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P+F ++  +  V EG  V L+   VG P P++ W  +G  +  +P++ I   G   +L I
Sbjct: 340 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 399

Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXX-----XQKRLHLPRPTKVXXXX 605
             A   D   Y C A N+ G+ +T A +Y               ++   + +P +V    
Sbjct: 400 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 459

Query: 606 XXXXXXXXYLRHVER--ARP-------------YIPPGEEDRVYPPPQFIVPLKSVTAME 650
                    +   +   A+P             Y+   +   +   P F   L++++A E
Sbjct: 460 TTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASE 519

Query: 651 GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--------FGYISLDMLSLN 702
           G  + FE R++  G P+ K+EW + G  IE S  F  + +            +L +  + 
Sbjct: 520 GQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVF 577

Query: 703 IQDSGEYTCRAVSATGVAETKAVLHV 728
            +DSG +TC A +  G   + A LHV
Sbjct: 578 AEDSGCFTCTASNKYGTVSSIAQLHV 603



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 75/274 (27%), Positives = 124/274 (45%), Gaps = 22/274 (8%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV-QQGHRFKTTYDF-GYV 2035
            P F K +K+  VTEG PV     +  +  P  +V W+ +G+ + ++  R K   +  G  
Sbjct: 1016 PIFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNERCKMRREGDGTC 1073

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA---KSGLYLDTLDEQRLKKIQELE 2092
            +L I    ++D G Y   A N  G    +  + V +   +S L       +   ++QE +
Sbjct: 1074 SLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERD 1133

Query: 2093 KYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
            K    +P++E     RP FL A   +    EG     +C+V  +  P LT  W  NGQ +
Sbjct: 1134 K----EPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 1184

Query: 2153 RAGHRYRT-THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
                 ++    + G  +L I      D+GTY C ATNK G+  N+ +L+++     +   
Sbjct: 1185 LPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ--NSFSLELSVVAKEV--K 1240

Query: 2212 QHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRF 2244
            + P  LEK++     +GH  R+E     + PP F
Sbjct: 1241 KAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVF 1274



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 80/310 (25%), Positives = 130/310 (41%), Gaps = 21/310 (6%)

Query: 2941 PDLKIEWYFNGK-VLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P  K+ W+ +GK + ++  R K+  +  G  +L +      D G YT  A N +G    S
Sbjct: 1043 PVPKVYWFKDGKQISKRNERCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCS 1102

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
              +   S       T   +   G  ++Q  +    KEP Q+        P F     D+V
Sbjct: 1103 GHLMVQSLPIRSRLTSAGQSHRGRSRVQERD----KEPLQE----RFFRPHFLQAPGDMV 1154

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILGTKTT 3116
               EG++   +  +  +G     + W  NG+ +  +A H++  V   G+  L I      
Sbjct: 1155 -AHEGRLCRLDCKV--SGLPPPELTWLLNGQPVLPDAPHKM-LVRETGVHSLLIDPLTQR 1210

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D+GTY C ATNK GQ   S++L  V K   + P     +QN  G+ +G     EC V+ +
Sbjct: 1211 DAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNC-GVPEGHPVRLECRVIGM 1269

Query: 3177 DDPDMKIEWYHNGQPMRHS-TRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P     W  + + +  +  RI    D  G+  L I   +  D+G Y   A N+ G   
Sbjct: 1270 PPP--VFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVS 1327

Query: 3235 TRATINCYGK 3244
              A ++ Y +
Sbjct: 1328 CTARLDIYAQ 1337



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 75/310 (24%), Positives = 128/310 (41%), Gaps = 20/310 (6%)

Query: 3349 EENSGEYECVATNKLGRDSTKANLKCTSKENLI--LDSQLPRGMEGGLEKLQTLEDSMVR 3406
            ++N  E +      LG+  T ++++   +E  I   + +L   +E  LE+    E     
Sbjct: 944  DDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLERTPVDESDDEI 1003

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL-KA 3465
            + D  +   K  AP+F   L +   + EG    F  ++     P  KV W+ +GK + K 
Sbjct: 1004 QHD-EIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKR 1059

Query: 3466 GSRFRTFCDF-GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQL 3524
              R +   +  G   L I  T  +D G Y   A N  G    +  + VQ   ++ + S+L
Sbjct: 1060 NERCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQ---SLPIRSRL 1116

Query: 3525 PKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPV 3584
                +    +    E          P  E    P F   P D++  E      +C++  +
Sbjct: 1117 TSAGQSHRGRSRVQERDK------EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGL 1170

Query: 3585 NDSSMRVEWFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643
                +   W  NG+P+L  +  K  + + G   L I  + QRDAG Y C ATN+ G+ + 
Sbjct: 1171 PPPELT--WLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSF 1228

Query: 3644 SCKLQVKGRQ 3653
            S +L V  ++
Sbjct: 1229 SLELSVVAKE 1238



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 46/290 (15%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            +E + Q P FT  ++   V E      +   I VG P  +V W   G  +E S  +  + 
Sbjct: 333  EEPLGQPPRFTQKLRSREVPEGTRVQLDC--IVVGIPPPQVRWYCEGKELENSPDIHIVQ 390

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ-HESALQKIQ 1822
                 +L +     ED+G Y+C A N  G   TS+ ++++  +S   E   ++  + +IQ
Sbjct: 391  AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQ 450

Query: 1823 Q-LEDSSRYQRREDVEVAVNQA------PRFIT--QLNGPTKLSEG-------------- 1859
            +  E SS       +  AV QA      PR  T  Q   PT   +G              
Sbjct: 451  KPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTK 510

Query: 1860 ----------QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR--------TSNDFGF 1901
                      Q   +ECR++  P P  +VEWY  G +++    +R         +     
Sbjct: 511  MLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPEEI 568

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
              L I  V+ EDSG +TC A N  G   S  +L+V+  E +  +    SA
Sbjct: 569  CTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 618



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 31/99 (31%), Positives = 53/99 (53%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP   + L+ + V EG  ++  C +VG P P V+WY   K ++ S    + +  + ++L 
Sbjct: 339  PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 398

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            I+EAF ED G Y C A N  G  + +A++ +     +D+
Sbjct: 399  IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDS 437



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--- 4467
            P+FTK +Q     E +   FE    G P P ++WYRE   I++SPDF+I     +S+   
Sbjct: 506  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 565

Query: 4468 -----LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
                 L+I +VF EDS  F   A N+ GT    A L V
Sbjct: 566  EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 603



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 12/152 (7%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--------MS 4672
            A P   + L++   +EGQ + F C++ G P P V+WY+   LI+ S  F+        M+
Sbjct: 504  AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 563

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN---LPALTPLRD 4729
               +  TL I+E F ED G + C A N  G V+  A+L V   +   N   L +     +
Sbjct: 564  EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 623

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            +   E QP+   ++  S  +P    L EG L+
Sbjct: 624  LAAIEPQPSPPHSEPPSVEQPPKPKL-EGVLV 654



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 64/230 (27%), Positives = 96/230 (41%), Gaps = 15/230 (6%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI-KTGHRFRPAYEFDYV 1368
            AP F + L +    EG+ V   C++  VG    +V WF +GK I K   R +   E D  
Sbjct: 1015 APIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNERCKMRREGDGT 1072

Query: 1369 -ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
             +L + S   +D G YT  A N  G    S  L V   + L + S+  S  +  +     
Sbjct: 1073 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQSHRGRSRV 1129

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
                K  + +     +P F+  P  +    EG+    +CK+  +    L   W  NGQPV
Sbjct: 1130 QERDKEPLQERF--FRPHFLQAPGDMV-AHEGRLCRLDCKVSGLPPPELT--WLLNGQPV 1184

Query: 1488 T--IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
                 H+   + + G  +L I  L   D+G Y C A N  G +  S  L+
Sbjct: 1185 LPDAPHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELS 1233



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 72/256 (28%), Positives = 109/256 (42%), Gaps = 28/256 (10%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTLNDFG 3751
            P F   +K +  V EG PV F C++  VG P  ++ WF +G+  +  +   ++    D G
Sbjct: 1016 PIFDKRLK-HFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNERCKMRREGD-G 1071

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
              +L I+   + D G YT  A N  G      +I+CS    +V    +   ++       
Sbjct: 1072 TCSLHIESTTSDDDGNYTIMAANPQG------RISCSGHL-MVQSLPIRSRLTSAGQSHR 1124

Query: 3812 ERGRISDAPKEEPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
             R R+ +  KE P+      P F+         E    R +C+V     P+L   W  NG
Sbjct: 1125 GRSRVQERDKE-PLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELT--WLLNG 1181

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS-----CKK 3923
            + +LP       V + G  SL I  +   D+G Y C A N  G++     +S      KK
Sbjct: 1182 QPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKK 1241

Query: 3924 LPDII--LQN-QVPRG 3936
             P I+  LQN  VP G
Sbjct: 1242 APVILEKLQNCGVPEG 1257



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 71/265 (26%), Positives = 118/265 (44%), Gaps = 28/265 (10%)

Query: 1168 QIEEISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV-G 1223
            Q +EI   K   P+F + L +   V+EG  +   C++  +G P  +V WF +G+ ++   
Sbjct: 1004 QHDEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRN 1060

Query: 1224 SRFKTYYDF-GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE---RSDIVTDT 1279
             R K   +  G  +L I   TS D G YT+ A N  G    S  + V     RS + +  
Sbjct: 1061 ERCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAG 1120

Query: 1280 QNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGD 1339
            Q+ +   ++Q  +    + +  R        P F +A  ++   EG    L+C++   G 
Sbjct: 1121 QSHRGRSRVQERDKEPLQERFFR--------PHFLQAPGDMVAHEGRLCRLDCKVS--GL 1170

Query: 1340 QTMRVEWFCNGKPI--KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
                + W  NG+P+     H+     E    +L +  +   D+G Y C ATN+ G+   S
Sbjct: 1171 PPPELTWLLNGQPVLPDAPHKML-VRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFS 1229

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQ 1422
              L V+AK+      + P  LEK+Q
Sbjct: 1230 LELSVVAKE----VKKAPVILEKLQ 1250



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 7/105 (6%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F K+ Q+   +EG++  F+CRV G P P+V W+     I D  + +IL  +  + A 
Sbjct: 505 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 564

Query: 450 ------LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
                 L+I  V   DSG  TC A NK G  +   +L+V   E +
Sbjct: 565 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 609



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 3/98 (3%)

Query: 3688 EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            E+    PPRFT +++   +VPEG  V  DC V  VG P  ++ W+  G+       +H +
Sbjct: 333  EEPLGQPPRFTQKLRSR-EVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIV 389

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                  +L I   +  D G Y+C A+N +G+ +T+A+I
Sbjct: 390  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 427



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 74/303 (24%), Positives = 115/303 (37%), Gaps = 46/303 (15%)

Query: 3413 EEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF 3472
            EE  G+ P FT  L + E + EG     +  +     P  +V WY  GK L+        
Sbjct: 333  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIV 389

Query: 3473 CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTI 3532
                   L I+  + ED+G Y C A N YG   T+A + ++G  +   E    K     I
Sbjct: 390  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRI 449

Query: 3533 DK---IAALEGYSGTVDTLTPEAE------------------------SGNP----PEFT 3561
             K   +++    S  +    P+A+                         G P    P FT
Sbjct: 450  QKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFT 509

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG-----KP---LLTGSRVKTINDFG 3613
                +L  SE     FECR+      S +VEW+  G      P   +L            
Sbjct: 510  KMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEE 567

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ 3673
               L I  V+  D+G +TC A+N++G  +   +L V+G + +     L  H  + T ++ 
Sbjct: 568  ICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSL--HSANSTTNLA 625

Query: 3674 KLE 3676
             +E
Sbjct: 626  AIE 628



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 61/225 (27%), Positives = 100/225 (44%), Gaps = 17/225 (7%)

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT-GSRVKTINDF-GFVILEIGGVYQRD 3626
            ++E S   F C+++ +     +V WF +GK +     R K   +  G   L I      D
Sbjct: 1027 VTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNERCKMRREGDGTCSLHIESTTSDD 1084

Query: 3627 AGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEIT 3686
             G YT  A N  G  + S  L V   Q + +  +L S  +S      +    + +R++  
Sbjct: 1085 DGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAGQS-----HRGRSRVQERDKEP 1136

Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746
            ++ E+   P F ++   ++   EG     DC+V   G P   + W  NG+P    +    
Sbjct: 1137 LQ-ERFFRPHF-LQAPGDMVAHEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDAPHKM 1192

Query: 3747 L-NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            L  + G  +L ID +  RDAG Y C ATNK G  + + +++  AK
Sbjct: 1193 LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 1237



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 40/122 (32%), Positives = 57/122 (46%), Gaps = 8/122 (6%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTYT 4570
            PP FT   ++  V  G  V+LD  V G  P  V W   GK+++  PDI   I++    ++
Sbjct: 339  PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIH--IVQAGNLHS 396

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAEC----VVSLPATKDKPKPQTKAANAPPEII 4626
            L I EA+ +D+G+Y C A N  G     AE     V S  +  D  K +      P E+ 
Sbjct: 397  LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVS 456

Query: 4627 EP 4628
             P
Sbjct: 457  SP 458



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 60/237 (25%), Positives = 99/237 (41%), Gaps = 13/237 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694
            P F   LK     EG  + F  +I  VG P  K+ W K+G+ I   +    + R G    
Sbjct: 1016 PIFDKRLKHFRVTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNERCKMRREGDGTC 1073

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            SL + S    D G YT  A +  G       L V       R +   ++ +   ++++  
Sbjct: 1074 SLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERD 1133

Query: 755  KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT 814
            K    E ++E+   RP F++   D+    EGR    + +++ +  P +   W  +G+P+ 
Sbjct: 1134 K----EPLQERFF-RPHFLQAPGDM-VAHEGRLCRLDCKVSGLPPPELT--WLLNGQPVL 1185

Query: 815  ASSRITSIFN-FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
              +    +    G  SL I  L   DAG+Y   A NK G+   +  + V A+    A
Sbjct: 1186 PDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKA 1242



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 9/145 (6%)

Query: 3146 GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG 3205
            GQ PRFT  +++ E + +G     +C VV +  P  ++ WY  G+ + +S  I  V    
Sbjct: 337  GQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQAGN 393

Query: 3206 FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELES 3265
               L IA     D+G Y C A N YG D T A I   G     + S   +      E+  
Sbjct: 394  LHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG-----VSSSDSEGDPNKEEMNR 448

Query: 3266 LQGAQQ-QTPSTPSAEPPKFITQIQ 3289
            +Q   +  +P T SA  P  + Q Q
Sbjct: 449  IQKPNEVSSPPTTSAVIPPAVPQAQ 473



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 60/244 (24%), Positives = 98/244 (40%), Gaps = 13/244 (5%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            LE+    ES +  +  EIP       P+F + L++   + EG    F C++  VG P  K
Sbjct: 991  LERTPVDESDDEIQHDEIPTGKCIA-PIFDKRLKHF-RVTEGSPVTFTCKI--VGIPVPK 1046

Query: 2410 VEWFRNEKLIEDSSRITKTH--DFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            V WF++ K I   +   K      G  S+ I     +D+G Y   A+N  G         
Sbjct: 1047 VYWFKDGKQISKRNERCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 1106

Query: 2468 XXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAH 2527
                  + + ++     +  +   +  ER  E     F +P F Q   G     EG+   
Sbjct: 1107 VQS---LPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQA-PGDMVAHEGRLCR 1162

Query: 2528 YEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THDFGFVTLDINSVVANDAGLYMCKAI 2586
             + +V  +  P L   W +NG  +   +  +    + G  +L I+ +   DAG Y C A 
Sbjct: 1163 LDCKVSGLPPPELT--WLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIAT 1220

Query: 2587 NRAG 2590
            N+ G
Sbjct: 1221 NKTG 1224



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 49/164 (29%), Positives = 74/164 (45%), Gaps = 12/164 (7%)

Query: 2235 EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT 2294
            EEP   PPRF  +LR +  V EG     +C V  +  P +R  +Y  GK L+++   HI 
Sbjct: 333  EEPLGQPPRFTQKLR-SREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 389

Query: 2295 FDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  SL I     ED G YS  A N  G  T + S  +  +G   S+S+     E++ 
Sbjct: 390  QAGNLHSLTIAEAFEEDTGRYSCFASNIYG--TDSTSAEIYIEGVSSSDSEGDPNKEEMN 447

Query: 2355 ELE-----SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQT 2393
             ++     S+ P     IP  V + + +  QP   +  IQ+ Q+
Sbjct: 448  RIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQP--RVATIQQCQS 489



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 6/159 (3%)

Query: 4343 QKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE 4402
            ++  +P P  +     EV+ A ++Q  K     +E  +  +     +    +       E
Sbjct: 278  ERSSVPIPIPADTRDNEVNHALEQQEAKR----REAEQAASEAAGGDTTPGSSPSSLYYE 333

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
             P+   +PP FT+K++   V E  + + +    G P P ++WY E   ++NSPD  I   
Sbjct: 334  EPL--GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQA 391

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
                 L I + F ED+  ++  A N  GT   SA + +E
Sbjct: 392  GNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 430



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 36/135 (26%), Positives = 60/135 (44%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+  QK R+ ++ EG   Q    + G P P+V W+  G+ L NS    I+   N  +L 
Sbjct: 339 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 398

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +    + D+G Y+  A N  G   TS  + +E  + S  +   ++   +  Q+  E    
Sbjct: 399 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSP 458

Query: 385 ISEKALAPQFVKVCQ 399
            +  A+ P  V   Q
Sbjct: 459 PTTSAVIPPAVPQAQ 473



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 61/242 (25%), Positives = 102/242 (42%), Gaps = 17/242 (7%)

Query: 1571 DEVTTQ---APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPL-KSGSRF 1626
            DE+ T    API    LK+  + EG    F  +++ +     KV W+ + K + K   R 
Sbjct: 1006 DEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIP--VPKVYWFKDGKQISKRNERC 1063

Query: 1627 T-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
                   G  +L I S   +D G YT  A N  G    SG  +V   +S+ + S+   A 
Sbjct: 1064 KMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV---QSLPIRSRLTSAG 1120

Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
                      +  +   Q+      P F     D+   E +    + ++  +  P+L   
Sbjct: 1121 QSHRGRSRVQERDKEPLQERFF--RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL--T 1176

Query: 1746 WLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            WL NG P+  +A +++  + + G  +L +  +   D+GTY C A N+ G+   S  L V 
Sbjct: 1177 WLLNGQPVLPDAPHKM-LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVV 1235

Query: 1804 SK 1805
            +K
Sbjct: 1236 AK 1237



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
            EEP+   PP+F  +++S  V E   V+ +C V     P++R  WY  GK L +      V
Sbjct: 333  EEPL-GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 389

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
                  SL I   + ED+G Y C A N +G D T A I
Sbjct: 390  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 427



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 8/93 (8%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--------L 4778
            L+++   EGQ   F+ ++     P ++W REG LI ++PDF+++ +   ++        L
Sbjct: 512  LQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTL 571

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +I   + ED+G FTC A+   G V + A+L V+
Sbjct: 572  VIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVR 604



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 3/123 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            + P+F + +++ EV EG  V L+  +  +  P +R  WYC G+ ++              
Sbjct: 338  QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIVQAGNLH 395

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD-TLDEQRLKKIQELEKY 2094
            +L I  A+ EDTG Y C A+N  G   T++ + ++  S    +   +++ + +IQ+  + 
Sbjct: 396  SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEV 455

Query: 2095 ERP 2097
              P
Sbjct: 456  SSP 458



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 15/222 (6%)

Query: 3985 LVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY--DFGYVAMNFGWVYPED 4042
            + E     F C++  VG P  KV WF +GK +  +N    +     G  +++      +D
Sbjct: 1027 VTEGSPVTFTCKI--VGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSLHIESTTSDD 1084

Query: 4043 SGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             G Y   A N  G       +     P       +   + S  +     +  Q   ++ +
Sbjct: 1085 DGNYTIMAANPQGRISCSGHLMVQSLP-------IRSRLTSAGQSHRGRSRVQERDKEPL 1137

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY- 4161
            +E   R  P F+  P  +   EG   R  C+V+G P P + WLLNG  ++  + +K+   
Sbjct: 1138 QERFFR--PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVR 1195

Query: 4162 -DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
              G++   I    Q D G  + I             L V+ +
Sbjct: 1196 ETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAK 1237



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P+F++ L + E  EGT V L+C +  VG    +V W+C GK ++           +  
Sbjct: 338  QPPRFTQKLRSREVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQAGNLH 395

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L +   + ED+G Y+C A+N  G   TS  + +
Sbjct: 396  SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 429



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 8/103 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
           K  + AP F +    L+  EG+ VV   R  G P+P++ W ++G  I  +P+ RI     
Sbjct: 500 KPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKP 559

Query: 545 AS--------TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            S        TL I    A D+  + CTA N  G+ ++ A+L+
Sbjct: 560 RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLH 602



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 59/237 (24%), Positives = 101/237 (42%), Gaps = 21/237 (8%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-RHSTRIKTVSDF-GF 3206
            P F   +++   + +G    F C +V +  P  K+ W+ +G+ + + + R K   +  G 
Sbjct: 1016 PIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNERCKMRREGDGT 1072

Query: 3207 VVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDS-LAKIRELES 3265
              L I  T + D G Y   A N  G       I+C   G + ++SL   S L    +   
Sbjct: 1073 CSLHIESTTSDDDGNYTIMAANPQGR------ISC--SGHLMVQSLPIRSRLTSAGQSHR 1124

Query: 3266 LQGAQQQTPSTPSAEP---PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNG 3322
             +   Q+    P  E    P F+    D+    EG+    + ++  +  P+L   W  NG
Sbjct: 1125 GRSRVQERDKEPLQERFFRPHFLQAPGDMVAH-EGRLCRLDCKVSGLPPPELT--WLLNG 1181

Query: 3323 KK-LPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            +  LP         + G+  L I    + ++G Y+C+ATNK G++S    L   +KE
Sbjct: 1182 QPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1238



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 7/161 (4%)

Query: 3965 YDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTP 4024
            Y+    QPPRF  +++S+      E T+ +     VG P  +V W+  GK L +      
Sbjct: 332  YEEPLGQPPRFTQKLRSREV---PEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI 388

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSI 4084
            +      ++     + ED+G Y C A+N+YG D T A I   G      DS+   + + +
Sbjct: 389  VQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEM 446

Query: 4085 EKIRE-MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEE 4124
             +I++  E S   T   V+  +  +   + V+ P   T+++
Sbjct: 447  NRIQKPNEVSSPPTTSAVIPPAVPQAQHL-VAQPRVATIQQ 486



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 10/110 (9%)

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR------ 1360
            ++ AP F++ L N+   EG  V  ECR++  G  + +VEW+  G  I+    FR      
Sbjct: 502  IIAAPVFTKMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKP 559

Query: 1361 --PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
               A   +   L +  V+ EDSG +TC A+N+ G   +   L V   +DL
Sbjct: 560  RSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 609



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 37/91 (40%), Positives = 49/91 (53%), Gaps = 11/91 (12%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKTHDFGY 2433
            PVFT+ LQN+ +  EGQ   F+CR+   G P+ KVEW+R   LIEDS   RI +      
Sbjct: 506  PVFTKMLQNL-SASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 562

Query: 2434 V------SMTISHVRDEDEGVYMCRASNLLG 2458
                   ++ I+ V  ED G + C ASN  G
Sbjct: 563  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 593



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 60/237 (25%), Positives = 96/237 (40%), Gaps = 19/237 (8%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPS-GTRYKSTHDFSYV-S 2832
            +F   L +    EG  + F C +     P  K+ WF + K +     R K   +     S
Sbjct: 1017 IFDKRLKHFRVTEGSPVTFTCKIVGI--PVPKVYWFKDGKQISKRNERCKMRREGDGTCS 1074

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE 2892
            L I  T  +D G YT  A N +G  + SG L            Q    ++ L +  Q+  
Sbjct: 1075 LHIESTTSDDDGNYTIMAANPQGRISCSGHLM----------VQSLPIRSRLTSAGQSHR 1124

Query: 2893 ARLAKGRRPSVPDTE-YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNG 2951
             R     R   P  E + +P + +    +    EG++  L+ +V     P+L   W  NG
Sbjct: 1125 GRSRVQERDKEPLQERFFRPHF-LQAPGDMVAHEGRLCRLDCKVSGLPPPEL--TWLLNG 1181

Query: 2952 K-VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
            + VL       L  + G  +L +  + +RD+G Y C A NK G+   S  +   +K+
Sbjct: 1182 QPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1238



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 27/85 (31%), Positives = 42/85 (49%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            LR   V EG   Q    +     P ++W  EG  +  +PD  ++  GN   L I   +EE
Sbjct: 346  LRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEE 405

Query: 4787 DTGTFTCRATTAAGQVETSAKLVVK 4811
            DTG ++C A+   G   TSA++ ++
Sbjct: 406  DTGRYSCFASNIYGTDSTSAEIYIE 430



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 57/214 (26%), Positives = 98/214 (45%), Gaps = 25/214 (11%)

Query: 1077 VEWYFNGKQITSAN---RIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            V W+ +GKQI+  N   +++   D G  +L I S  ++D G YT++A N  G    S  +
Sbjct: 1047 VYWFKDGKQISKRNERCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 1105

Query: 1134 TVET---RSSIDTS-SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPV 1189
             V++   RS + ++   HRG   ++R  E  K  EP+ +       +P F+Q        
Sbjct: 1106 MVQSLPIRSRLTSAGQSHRG---RSRVQERDK--EPLQE----RFFRPHFLQ-APGDMVA 1155

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGFVALDIIHATSADTG 1248
             EG+   L+C++   G P   + W  NG+ V   +  K    + G  +L I   T  D G
Sbjct: 1156 HEGRLCRLDCKVS--GLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAG 1213

Query: 1249 EYTVRAVNHLG----SAHTSAIVRVIERSDIVTD 1278
             Y   A N  G    S   S + + ++++ ++ +
Sbjct: 1214 TYKCIATNKTGQNSFSLELSVVAKEVKKAPVILE 1247



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 67/275 (24%), Positives = 112/275 (40%), Gaps = 26/275 (9%)

Query: 751  EDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG 810
            E   + QH E I       P F + L+    + EG    F  ++  +  P  +V W+KDG
Sbjct: 998  ESDDEIQHDE-IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGI--PVPKVYWFKDG 1053

Query: 811  RPITASSRITSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
            + I+  +    +   G    SL+I    ++D G+YT+ A N  G    +  + V +    
Sbjct: 1054 KQISKRNERCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS---- 1109

Query: 869  TADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAH 928
                 +P + R +                    + E   +P F     D ++  EG    
Sbjct: 1110 -----LPIRSR-LTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVA-HEGRLCR 1162

Query: 929  FEARLEPIGDSTLRVEWLKDGRPV--EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
             + ++  +    L   WL +G+PV  +A  ++      G  +L I  +T  DAG Y C A
Sbjct: 1163 LDCKVSGLPPPELT--WLLNGQPVLPDAPHKMLVR-ETGVHSLLIDPLTQRDAGTYKCIA 1219

Query: 987  YNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             N  GQ + S  L++V K+      + P  LEK+Q
Sbjct: 1220 TNKTGQNSFSLELSVVAKE----VKKAPVILEKLQ 1250



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 34/221 (15%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT--THNHTTL 323
            P   Q P +    EG   +   ++SG P P +TW  NGQ ++    H+++   T  H+ L
Sbjct: 1144 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLL 1203

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                TQ+ D+G Y         CI T+                     T       E  +
Sbjct: 1204 IDPLTQR-DAGTYK--------CIATNK--------------------TGQNSFSLELSV 1234

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
               E   AP  ++  Q+  V EG   R +CRV G P P V ++  D +       +I ++
Sbjct: 1235 VAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMP-PPVFYWKKDNETIPCTRERISMH 1293

Query: 444  E--SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            +  +G   L+I     SD+G  T  A+N++G  +   RL++
Sbjct: 1294 QDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1334



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 12/145 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG--- 3751
            P FT ++  N+   EG  V F+CRV+  G P+ +++W+  G           L       
Sbjct: 506  PVFT-KMLQNLSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 562

Query: 3752 -----FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
                    L I  ++A D+G +TC A+NK+G+ ++ A++      D+     L    S  
Sbjct: 563  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTT 622

Query: 3807 KIKELERGRISDAPKEEPIVSTPPK 3831
             +  +E  + S    E P V  PPK
Sbjct: 623  NLAAIE-PQPSPPHSEPPSVEQPPK 646



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 58/230 (25%), Positives = 87/230 (37%), Gaps = 11/230 (4%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT-GARLK 2692
            + TG   APIF   LK + ++ EG  V    ++     P  K+ WFK+G  ++    R K
Sbjct: 1008 IPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNERCK 1064

Query: 2693 STFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLD 2751
               +  G  +L I S  +DD G YT  A N  G    +  + ++     +   L      
Sbjct: 1065 MRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSAGQS 1122

Query: 2752 RIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFF 2811
              G                     F+    ++V  EG     +C V  S  P  ++ W  
Sbjct: 1123 HRGR-SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKV--SGLPPPELTWLL 1179

Query: 2812 NNKP-LPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
            N +P LP         +    SL I    + D+G Y C ATN  G  + S
Sbjct: 1180 NGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFS 1229



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 4/117 (3%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            Q P FTQ L++ + + EG     DC  I VG P  +V W+   K +E+S  I        
Sbjct: 338  QPPRFTQKLRSRE-VPEGTRVQLDC--IVVGIPPPQVRWYCEGKELENSPDIHIVQAGNL 394

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE-TQHPEGMKKIQK 2489
             S+TI+   +ED G Y C ASN+ G                  E   + E M +IQK
Sbjct: 395  HSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQK 451



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 33/112 (29%), Positives = 48/112 (42%)

Query: 50   TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
            T V+ S D         G+   PIF++  K+ R  +G    F  K+ G P P V W +  
Sbjct: 994  TPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDG 1053

Query: 110  APLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              + + N+      E  G  SL I+     D+G YT  A N  G   CS ++
Sbjct: 1054 KQISKRNERCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHL 1105



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 14/151 (9%)

Query: 1678 ESQHEGALPR---LNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARL 1734
            ++QH  A PR   + Q +  + Y +     + I  APVFT  ++++  +E Q   FE R+
Sbjct: 471  QAQHLVAQPRVATIQQCQSPTNYLQ-GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRV 529

Query: 1735 IPVGDPKLRVEWLRNGVPIEAS-------NRLTTMHDFGYV-ALNMKYVNPEDSGTYTCR 1786
               G P  +VEW R G  IE S        +  +M +   +  L +  V  EDSG +TC 
Sbjct: 530  --KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCT 587

Query: 1787 AINELGEAVTSSTLFVQSKASLQLESQHESA 1817
            A N+ G   + + L V+    L       SA
Sbjct: 588  ASNKYGTVSSIAQLHVRGNEDLSNNGSLHSA 618



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIR----- 4559
            G+  I  P FT   QN++ + GQLV  + +V G     V W + G  ++  PD R     
Sbjct: 499  GKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKK 558

Query: 4560 -NKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
               + E +   TL+I E + +DSG + C A N  G
Sbjct: 559  PRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 593



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 43/149 (28%), Positives = 62/149 (41%), Gaps = 13/149 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APVFT  L N+ +  EG+   FE R+     P  KVEWY  G  ++    FR        
Sbjct: 505  APVFTKMLQNL-SASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRS 561

Query: 3479 ILE--------ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530
            + E        I+  + EDSG + C A N YG   + A + V+G  ++     L      
Sbjct: 562  MAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANST 621

Query: 3531 TIDKIAALEGYSGTVDTLTPEAESGNPPE 3559
            T   +AA+E       +  P  E    P+
Sbjct: 622  T--NLAAIEPQPSPPHSEPPSVEQPPKPK 648



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P  +PP+F  +++   ++ EG     +  +V +  P  +V W+  GK+L +         
Sbjct: 335  PLGQPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQA 391

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              +  L I   +EE++G Y C A+N  G DST A +
Sbjct: 392  GNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 427



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 3/82 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HAL 450
           P+F +  + R+V EG   + DC V G P P+V W+   +++ +  +  I + ++GN H+L
Sbjct: 340 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELEN--SPDIHIVQAGNLHSL 397

Query: 451 MITNVTLSDSGVVTCVARNKSG 472
            I      D+G  +C A N  G
Sbjct: 398 TIAEAFEEDTGRYSCFASNIYG 419



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 11/97 (11%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            +PI++ P  F   +++ +  E + V FECRV+    PK  +EWYR G L+     +R + 
Sbjct: 500  KPIIAAPV-FTKMLQNLSASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQ 556

Query: 3883 DMG--------FVSLDILYVYAEDSGEYICRAVNDFG 3911
                         +L I  V+AEDSG + C A N +G
Sbjct: 557  KKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 593



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 57/250 (22%), Positives = 103/250 (41%), Gaps = 22/250 (8%)

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276
            LE+    E+       E+   K   P F   L+    V EG    F C++  +  P  ++
Sbjct: 991  LERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVP--KV 1047

Query: 2277 EFYHNGKALQSA---ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAIS 2331
             ++ +GK +       +     D G  SL I+    +D G Y++ A N  G   C+  + 
Sbjct: 1048 YWFKDGKQISKRNERCKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLM 1106

Query: 2332 M-TVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390
            + ++  +  + S  Q   G  +++E +  EP +           RP F Q   ++    E
Sbjct: 1107 VQSLPIRSRLTSAGQSHRGRSRVQERDK-EPLQERFF-------RPHFLQAPGDMV-AHE 1157

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            G+    DC++   G P  ++ W  N + ++ D+       + G  S+ I  +   D G Y
Sbjct: 1158 GRLCRLDCKVS--GLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTY 1215

Query: 2450 MCRASNLLGE 2459
             C A+N  G+
Sbjct: 1216 KCIATNKTGQ 1225



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 73/303 (24%), Positives = 116/303 (38%), Gaps = 47/303 (15%)

Query: 2870 NIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYP--KPEWIIPIAAEHQLVEGQ 2927
            N   + Q  + +   +A  +A       G  PS    E P  +P          ++ EG 
Sbjct: 296  NHALEQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGT 355

Query: 2928 VLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCK 2987
             + L+  V     P  ++ WY  GK LE      +       +L + + +E D+G Y+C 
Sbjct: 356  RVQLDCIVV--GIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCF 413

Query: 2988 AYNKRGEAFTSSTVY---CTSKDN-------LIERTQHPKGTE-----------GLEKIQ 3026
            A N  G   TS+ +Y    +S D+        + R Q P                + + Q
Sbjct: 414  ASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQ 473

Query: 3027 NLEDSLRKEPGQQPDDDT-------GRP----PEFTTVFKDIVDISEGQIAHYEASLIPT 3075
            +L    R    QQ    T       G+P    P FT + +++   SEGQ+  +E  +   
Sbjct: 474  HLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNL-SASEGQLVVFECRV--K 530

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVY--------AFGMVVLEILGTKTTDSGTYSCRATN 3127
            G  S  +EW+  G  IE S   R +            +  L I      DSG ++C A+N
Sbjct: 531  GAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASN 590

Query: 3128 KWG 3130
            K+G
Sbjct: 591  KYG 593



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 5/123 (4%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            E  + Q PRF  +L    ++ EG     +C +   P P +R  WY  GK L++       
Sbjct: 333  EEPLGQPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 389

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
                  +L I   + ED+G Y+C A N  G   +S  + ++   S   DS+ +   E++ 
Sbjct: 390  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMN 447

Query: 1957 YLE 1959
             ++
Sbjct: 448  RIQ 450



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+V +EG+  +   +++    P + WL  G  ++P+ P   ++ E     LLI    + D
Sbjct: 1152 DMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRD 1211

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             GT+ C AT   GQ   S +L V +K
Sbjct: 1212 AGTYKCIATNKTGQNSFSLELSVVAK 1237



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 18/143 (12%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG--- 3205
            P FT  +QN+    +GQ   FEC V     P  K+EWY  G  +  S   + +       
Sbjct: 506  PVFTKMLQNLSA-SEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSM 562

Query: 3206 -----FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD-SLAK 3259
                    L IA     DSG + C A NKYG   + A ++  G      E L  + SL  
Sbjct: 563  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGN-----EDLSNNGSLHS 617

Query: 3260 IRELESLQGAQQQTPSTPSAEPP 3282
                 +L   + Q PS P +EPP
Sbjct: 618  ANSTTNLAAIEPQ-PSPPHSEPP 639



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 21/142 (14%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-------- 2160
            PVF   L +L +  EG    FECRV+    P   ++W+  G  I     +R         
Sbjct: 506  PVFTKMLQNL-SASEGQLVVFECRVKGAPSPK--VEWYREGTLIEDSPDFRILQKKPRSM 562

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKI 2220
                    L I   +AEDSG + C A+NK G   +   L V G+ ++       NG    
Sbjct: 563  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL-----SNNG---- 613

Query: 2221 RQLEAQGHSTRIEVEEPKISPP 2242
              L +   +T +   EP+ SPP
Sbjct: 614  -SLHSANSTTNLAAIEPQPSPP 634



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 10/99 (10%)

Query: 64  GRPGEP--SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE------- 114
           G  G+P  + P+F ++ +N   ++G    FE +++G P+P V W R +  L+E       
Sbjct: 496 GLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYR-EGTLIEDSPDFRI 554

Query: 115 CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
             K      E     +L+I ++   D G +TCTA N+YG
Sbjct: 555 LQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYG 593



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 10/105 (9%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--------STH 2826
            VF   L N+   EG  + FEC V+ +  P  K+EW+     +     ++           
Sbjct: 507  VFTKMLQNLSASEGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAE 564

Query: 2827 DFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
                 +L I   + EDSG +TC A+N  G+ ++   L   G++++
Sbjct: 565  PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 609



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 8/108 (7%)

Query: 3036 PGQQP-----DDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090
            PG  P     ++  G+PP FT   +   ++ EG     +   I  G     + W+  GK 
Sbjct: 323  PGSSPSSLYYEEPLGQPPRFTQKLRSR-EVPEG--TRVQLDCIVVGIPPPQVRWYCEGKE 379

Query: 3091 IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            +E S  I  V A  +  L I      D+G YSC A+N +G    S ++
Sbjct: 380  LENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 427



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL--------TSDFGFVTLDLVDV 2976
            EGQ++  E +V  K  P  K+EWY  G ++E    F++               TL + +V
Sbjct: 519  EGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 576

Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL 3009
            +  DSG +TC A NK G   + + ++    ++L
Sbjct: 577  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 609



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 7/160 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L +    EG  +  +C V     P  ++ W+   K L +          +  SL I
Sbjct: 342  FTQKLRSREVPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIVQAGNLHSLTI 399

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               +EED+G Y+C A+N  G+ +TS  +   G  +   D++    K  +  +++  E   
Sbjct: 400  AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMNRIQKPNEVSS 457

Query: 2896 AKGRRPSVPDTEYPKPEWII--PIAAEHQLVEGQVLHLEG 2933
                   +P    P+ + ++  P  A  Q  +    +L+G
Sbjct: 458  PPTTSAVIPPA-VPQAQHLVAQPRVATIQQCQSPTNYLQG 496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGD 128
            +P I E++ +N    +G   + E ++ G P PV  W +K    + C +  +  + + TG 
Sbjct: 1242 APVILEKL-QNCGVPEGHPVRLECRVIGMPPPVFYW-KKDNETIPCTRERISMHQDTTGY 1299

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
              LLI+     D G YT +A+N+ G   C+
Sbjct: 1300 ACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1329



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 2097 PKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            P  +  E+P GQ P F   L S E + EG R   +C V  I  P   + W+  G+++   
Sbjct: 327  PSSLYYEEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPPQ--VRWYCEGKELENS 383

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                        +L I   + ED+G Y C A+N  G    +  + + G
Sbjct: 384  PDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG 431



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 62/232 (26%), Positives = 89/232 (38%), Gaps = 17/232 (7%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH-- 1491
            D I     I P F  R K    V EG  V F CK+  +     KV WFK+G+ ++  +  
Sbjct: 1006 DEIPTGKCIAPIFDKRLKHFR-VTEGSPVTFTCKIVGIPVP--KVYWFKDGKQISKRNER 1062

Query: 1492 -RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             + R   D G  +L I    ++D G YT  A N  G    S  L  +S    +RS    A
Sbjct: 1063 CKMRREGD-GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP--IRSRLTSA 1119

Query: 1551 GLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL 1609
            G    Q    RS+    D    +     P    +  ++   EG+    + ++  +    L
Sbjct: 1120 G----QSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL 1175

Query: 1610 KVEWYHNNKP-LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
               W  N +P L            G  +L I      D+GTY C A N  G+
Sbjct: 1176 --TWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQ 1225



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 630 EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
           E+ +  PP+F   L+S    EG ++  +  +  VG P  ++ W   G+ +E S     + 
Sbjct: 333 EEPLGQPPRFTQKLRSREVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQ 390

Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
                SL +     +D+G Y+C A +  G   T A +++
Sbjct: 391 AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 429



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            +E +   PRF  + +S E V EG  V  +C +  +     +V W+  G+ +        +
Sbjct: 333  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDIHIV 389

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                  +L I +   ED+G Y+C A N+ GTD  S  +
Sbjct: 390  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEI 427



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 11/132 (8%)

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
            +A I++ +S     Q     P    P F   +Q+++   EGQ   FE R+     P  KV
Sbjct: 481  VATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSAS-EGQLVVFECRVKGAPSP--KV 537

Query: 3317 EWFYNGKKLPHGHRYRTFHDFG--------IVILDILYCYEENSGEYECVATNKLGRDST 3368
            EW+  G  +     +R              I  L I   + E+SG + C A+NK G  S+
Sbjct: 538  EWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSS 597

Query: 3369 KANLKCTSKENL 3380
             A L     E+L
Sbjct: 598  IAQLHVRGNEDL 609



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 10/93 (10%)

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG--------YVALDIIDL 1509
            EGQ V FEC+++       KVEW++ G  +     FR +               L I ++
Sbjct: 519  EGQLVVFECRVKGAPSP--KVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEV 576

Query: 1510 IAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
             AEDSG +TC A N  GT     +L  R   D+
Sbjct: 577  FAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 609



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 4/109 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF-ATGS 3742
            E+++  ++       +E   N  VPEG PV  +CRV  +G P     W  +      T  
Sbjct: 1231 ELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV--IGMPPPVFYWKKDNETIPCTRE 1288

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            R+    D  G+  L I      DAG YT  A N+ G  + TA++   A+
Sbjct: 1289 RISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 1337



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 4/140 (2%)

Query: 1571 DEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +E   Q P  T  L++ E+ EG R   +   I V     +V WY   K L++        
Sbjct: 333  EEPLGQPPRFTQKLRSREVPEGTRVQLD--CIVVGIPPPQVRWYCEGKELENSPDIHIVQ 390

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQ 1690
                 +L I     ED+G Y+C A N  G   TS    +    S   +S+ +     +N+
Sbjct: 391  AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS--SDSEGDPNKEEMNR 448

Query: 1691 LEDTSKYQRHSAQDEVITQA 1710
            ++  ++         VI  A
Sbjct: 449  IQKPNEVSSPPTTSAVIPPA 468



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 6/122 (4%)

Query: 1170 EEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            EE     P F Q L +   V EG  + L+C +  +G P  +V W+  G+ +         
Sbjct: 333  EEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIV 389

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV--IERSDIVTDTQNEQAIEQ 1287
                  +L I  A   DTG Y+  A N  G+  TSA + +  +  SD   D  N++ + +
Sbjct: 390  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD-PNKEEMNR 448

Query: 1288 IQ 1289
            IQ
Sbjct: 449  IQ 450



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 2632 MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691
            ++ +  + Q P FT  L+S + + EG  V L+  V     P  ++ W+  G  L     +
Sbjct: 330  LYYEEPLGQPPRFTQKLRSRE-VPEGTRVQLDCIVVGIPPP--QVRWYCEGKELENSPDI 386

Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
                   L +L+I     +D+G Y+C A+N+ G   ++A I IE
Sbjct: 387  HIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 430



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E  + Q PRF   L+ + ++ EG     +  V         V WY  GK++ ++  I   
Sbjct: 333  EEPLGQPPRFTQKLR-SREVPEGTRVQLDCIVVGIPP--PQVRWYCEGKELENSPDIHIV 389

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
                  +L IA    ED+G Y+  A N  G    SA + +E  SS D+
Sbjct: 390  QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDS 437



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 6/123 (4%)

Query: 763 EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822
           EE   Q P+F + L+   E+ EG     +  +  +  P +R  WY +G+ +  S  I  +
Sbjct: 333 EEPLGQPPRFTQKLRSR-EVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIV 389

Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP--EQRRY 880
                 SL I     ED G Y+  A N  G   ++A I +   S+  ++ G P  E+   
Sbjct: 390 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSE-GDPNKEEMNR 448

Query: 881 IEK 883
           I+K
Sbjct: 449 IQK 451



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            + ++  + P  +  LQ+ G + EG     E ++  +  P     W KD   I  +    S
Sbjct: 1235 VAKEVKKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERIS 1291

Query: 822  IFN--FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            +     GY  L I   +  DAG YT+ A N+ G    TA + + A+
Sbjct: 1292 MHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQ 1337



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 11/91 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-------- 2559
            P+FT++L   S   EGQ   +E RV   G PS + EWY  G  ++    FR         
Sbjct: 506  PVFTKMLQNLSAS-EGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 562

Query: 2560 THDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   TL I  V A D+G + C A N+ G
Sbjct: 563  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG 593



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--------TE 1628
            AP+ T  L+N+   EGQ   FE R+      + KVEWY     ++    F        + 
Sbjct: 505  APVFTKMLQNLSASEGQLVVFECRV--KGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 562

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
                    L I     EDSG +TC A N  G    S IA +H
Sbjct: 563  AEPEEICTLVIAEVFAEDSGCFTCTASNKYG--TVSSIAQLH 602



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G   + + K+ G P P ++W     P++    + M   E TG  SLLI  +   D G Y
Sbjct: 1157 EGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRE-TGVHSLLIDPLTQRDAGTY 1215

Query: 145  TCTARNQYGE 154
             C A N+ G+
Sbjct: 1216 KCIATNKTGQ 1225



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            PVF  +   ++  EG+   F CRV G P P+V W   G  I +   +++
Sbjct: 506  PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRI 554



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 4/88 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-- 1764
            + +APV    +++  V E      E R+I  G P     W ++   I  +    +MH   
Sbjct: 1239 VKKAPVILEKLQNCGVPEGHPVRLECRVI--GMPPPVFYWKKDNETIPCTRERISMHQDT 1296

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELG 1792
             GY  L ++     D+G YT  A NE G
Sbjct: 1297 TGYACLLIQPAKKSDAGWYTLSAKNEAG 1324



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 1/84 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            +P  +  E     PP F     +  V EG   +  C V G P P+V W   G  + N   
Sbjct: 326  SPSSLYYEEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPD 385

Query: 4157 YKLTYDGMYH-FDIPKTRQYDTGK 4179
              +   G  H   I +  + DTG+
Sbjct: 386  IHIVQAGNLHSLTIAEAFEEDTGR 409



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/101 (22%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ--------RLINSNKHEI 314
           ++ P   +  +N    EG    F+ ++ G P P+V W++ G         R++      +
Sbjct: 503 IAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 562

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
                  TL +      DSG +T  A N  G + +   L V
Sbjct: 563 AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 603



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT-VGSRFKTYYDF 1232
            K  PV ++ L N   V EG  + LECR+  M  P     W  +  ++     R   + D 
Sbjct: 1240 KKAPVILEKLQNCG-VPEGHPVRLECRVIGMPPPVFY--WKKDNETIPCTRERISMHQDT 1296

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             G+  L I  A  +D G YT+ A N  G    +A
Sbjct: 1297 TGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTA 1330



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 3/95 (3%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            Q P F   ++ +  + EG     +  +  +G    +V W  +G+ +E S  I        
Sbjct: 338  QPPRFTQKLRSR-EVPEGTRVQLDCIV--VGIPPPQVRWYCEGKELENSPDIHIVQAGNL 394

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +LTI      D G Y+C A N  G  +TSA + I
Sbjct: 395  HSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 429



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 11/164 (6%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI-VNGSRYKLTY--DGMYHF 4167
            P+F        V EG    F C++ G P P+V W  +G  I     R K+    DG    
Sbjct: 1016 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSL 1075

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRT 4227
             I  T   D G   ++             L V  +    R  L +A +     +   +R 
Sbjct: 1076 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV--QSLPIRSRLTSAGQSHRGRSRVQERD 1133

Query: 4228 ETELEKTFEERQVLQRQG-VIDH-----RPELKPKVIKEPETEW 4265
            +  L++ F     LQ  G ++ H     R + K   +  PE  W
Sbjct: 1134 KEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTW 1177



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            + P FTQ L    E+ EG     +  VV +  P +R  WY  G EL+             
Sbjct: 338  QPPRFTQKLRS-REVPEGTRVQLDCIVVGIPPPQVR--WYCEGKELENSPDIHIVQAGNL 394

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I      D G Y C A N  G
Sbjct: 395  HSLTIAEAFEEDTGRYSCFASNIYG 419



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129
           PP F Q  ++    +G   + +  + G P P V W  +   L       +    Q G++ 
Sbjct: 339 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI---VQAGNLH 395

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           SL I +    D G Y+C A N YG    S  I  EG
Sbjct: 396 SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG 431



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG-----KP---LLHKNRFTP 4024
            P F   +Q+  S  E +   FEC++   G P+ KVEW+  G      P   +L K   + 
Sbjct: 506  PVFTKMLQN-LSASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 562

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQL 4077
                    +    V+ EDSG + C A+N YG   + A +   G   +  +  L
Sbjct: 563  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSL 615



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY------ 1230
            PVF + L N    SEG+ +  ECR++  G P+ +VEW+  G  +     F+         
Sbjct: 506  PVFTKMLQNLS-ASEGQLVVFECRVK--GAPSPKVEWYREGTLIEDSPDFRILQKKPRSM 562

Query: 1231 --DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
                    L I    + D+G +T  A N  G+  + A + V    D+
Sbjct: 563  AEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDL 609


>BC013867-1|AAH13867.2|  510|Homo sapiens PALLD protein protein.
          Length = 510

 Score =  206 bits (504), Expect = 1e-51
 Identities = 118/375 (31%), Positives = 198/375 (52%), Gaps = 13/375 (3%)

Query: 214 DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
           + ++  ++KV + E RL+ E+ +R  + +  V ES  ++    D  +     P    K +
Sbjct: 79  EETANQEYKVSSCEQRLISEIEYR--LERSPVDESGDEVQYG-DVPVENGMAPFFEMKLK 135

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS-- 331
           + K+ EG    F  +++GNP+P++ WFK+G+++   + H  I      T  +  T  +  
Sbjct: 136 HYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLD 195

Query: 332 DSGHYTLLAENPNGCIVTSGYLAVESPTE---SYVQDQRSQYITDTQQRETE---ERIEI 385
           D G+YT++A NP G I  +G L V++  +   S        ++   + R  +   E   I
Sbjct: 196 DDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPI 255

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            E+   P F++   D  V EGK+ R DC+V+G P P+++W ++ + +R D  HK+LV E+
Sbjct: 256 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 315

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
           G H+L+I  VT  D+G+ TC+A N++G+ +F   L V  KE    P F+E+     V +G
Sbjct: 316 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 375

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDG-GASTLDIPRAKASDAAWYQC 563
            PV L  R +G P P+I W+K+   +  + + + +H D  G   L I  A   DA WY  
Sbjct: 376 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 435

Query: 564 TAQNVAGSTATRARL 578
           +A+N AG  +  ARL
Sbjct: 436 SAKNEAGIVSCTARL 450



 Score =  104 bits (250), Expect = 7e-21
 Identities = 79/325 (24%), Positives = 137/325 (42%), Gaps = 28/325 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTL 4571
            P F +  ++  +  G  V    +V G     +YW K+GK++ P   +  ++ D  GT +L
Sbjct: 128  PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 187

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-----------KPQTKAA- 4619
                +   D G Y  +A N  G   C    +V     + +            +P++++  
Sbjct: 188  HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 247

Query: 4620 ----NAP-------PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP-SK 4667
                N P       P  ++   D  V EG+     CK+ G P P + W    K ++P S 
Sbjct: 248  SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 307

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +  + R    ++L I      D G Y C+A N AG+ + + +L V   +       +  L
Sbjct: 308  HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 367

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYE 4785
            ++  V +G P + + ++     P I W +E   +  + D   +H+ N+    LLI    +
Sbjct: 368  QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 427

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
            ED G +T  A   AG V  +A+L V
Sbjct: 428  EDAGWYTVSAKNEAGIVSCTARLDV 452



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 90/354 (25%), Positives = 150/354 (42%), Gaps = 24/354 (6%)

Query: 2940 DPDLKIEWYFNGKVLEQGS-RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +P  KI W+ +GK +   S  + +  D  G  +L        D G YT  A N +G    
Sbjct: 154  NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISC 213

Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQ-QPDDDTGRPPEFTTVFKD 3056
            +  +   + +   +R + P+   G   ++      R    + +P  +    P F     D
Sbjct: 214  TGRLMVQAVN---QRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGD 270

Query: 3057 IVDISEGQIAHYEASL--IPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILG 3112
            +  + EG++   +  +  +PT D S    W  +GK +  +++H++  V   G+  L I  
Sbjct: 271  LT-VQEGKLCRMDCKVSGLPTPDLS----WQLDGKPVRPDSAHKM-LVRENGVHSLIIEP 324

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172
              + D+G Y+C ATN+ GQ   S++L    K   + P F   +QN  G+ DG     EC 
Sbjct: 325  VTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN-TGVADGYPVRLECR 383

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHST-RIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
            V+ V  P  +I W    + + HST R+    D  G++ L I      D+G Y   A N+ 
Sbjct: 384  VLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 441

Query: 3231 GEDFTRATINCYGKGGVYLESLQPDSL---AKIRELESLQGAQQQTPSTPSAEP 3281
            G     A ++ Y +     +S +P  +   A      S QG   +    P A P
Sbjct: 442  GIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANP 495



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 63/236 (26%), Positives = 101/236 (42%), Gaps = 9/236 (3%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA-SNRLTTMHDF-GY 1767
            AP F M +K  ++ E     F  R+   G+PK ++ W ++G  I   S+  T   D  G 
Sbjct: 127  APFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 184

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+      +D G YT  A N  G    +  L VQ+        +  S    +++    
Sbjct: 185  CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 244

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887
            SR    E+  +          Q  G   + EG+    +C++   P P++   W  +GK +
Sbjct: 245  SRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKPV 302

Query: 1888 Q--SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            +  S H+     + G  +L I  V   D+G YTC A N  GQ   S+ L V +KE+
Sbjct: 303  RPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 357



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 72/247 (29%), Positives = 105/247 (42%), Gaps = 15/247 (6%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            V  E G AP F + L + + + EG    F  R+    +P  K+ W+ +GK +   S   T
Sbjct: 120  VPVENGMAPFFEMKLKHYK-IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYT 176

Query: 3472 FC-DF-GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGME 3529
               D  G   L  + +  +D G Y   A N  G    T  + VQ         + P G  
Sbjct: 177  IQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG-H 235

Query: 3530 GTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDS 3587
              + +  +    SG  D   P  E    P F   P DL + E      +C++  +P  D 
Sbjct: 236  PHVRRPRSRSRDSG--DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL 293

Query: 3588 SMRVEWFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            S    W  +GKP+   S  K  + + G   L I  V  RDAG+YTC ATNR G+ + S +
Sbjct: 294  S----WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLE 349

Query: 3647 LQVKGRQ 3653
            L V  ++
Sbjct: 350  LVVAAKE 356



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 11/234 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--FGYI 694
           P F + LK     EG  + F  R+   G+P  KI W K+G+ I   S   +I R   G  
Sbjct: 128 PFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 185

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
           SL   +  + D G YT  A +  G       L V       R+ + P    ++++    S
Sbjct: 186 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 245

Query: 755 K--YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
           +      E I+E+   RP F++   DL  +QEG+    + +++ +  PT  + W  DG+P
Sbjct: 246 RDSGDENEPIQERFF-RPHFLQAPGDL-TVQEGKLCRMDCKVSGL--PTPDLSWQLDGKP 301

Query: 813 ITA-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           +   S+    +   G  SL I  + + DAG YT  A N+ G+   +  + VAA+
Sbjct: 302 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 355



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 55/192 (28%), Positives = 80/192 (41%), Gaps = 8/192 (4%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILI 4469
            P F +      V E +  R + +  G P P + W  +  P++ +S    +   +    LI
Sbjct: 262  PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 321

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I  V   D+ ++  +A NR G    S  LVV  K         PP F    QN  V  G 
Sbjct: 322  IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-----PPVFIEKLQNTGVADGY 376

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYECV 4587
             VRL+ +V G  P  ++W K  + +        + +D  G   LLI  A  +D+G Y   
Sbjct: 377  PVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVS 436

Query: 4588 AINSAGEARCDA 4599
            A N AG   C A
Sbjct: 437  AKNEAGIVSCTA 448



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 68/225 (30%), Positives = 100/225 (44%), Gaps = 14/225 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN-DF-GF 3752
            P F +++K +  + EG PV F CRV   G+P  +I WF +G+  +  S  +T+  D  G 
Sbjct: 128  PFFEMKLK-HYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 184

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
             +L        D G YT  A N  G  + T ++   A   +    + P+  SG       
Sbjct: 185  CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQA---VNQRGRSPRSPSGHPHVRRP 241

Query: 3813 RGRISDAPKE-EPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
            R R  D+  E EPI      P F+      TV+E +  R +C+V     P L   W  +G
Sbjct: 242  RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDG 299

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            K + P       V + G  SL I  V + D+G Y C A N  G++
Sbjct: 300  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 344



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 90/358 (25%), Positives = 144/358 (40%), Gaps = 50/358 (13%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KTGHRFRPAYEFDY 1367
            AP F   L + +  EG  V   CR+   G+   ++ WF +GK I  K+ H +    + D 
Sbjct: 127  APFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDH-YTIQRDLDG 183

Query: 1368 V-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426
              +L   +   +D G YT  A N  G    +  L V A        + PSG   ++    
Sbjct: 184  TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 243

Query: 1427 TSRYK--KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484
             SR    + + I E    +P F+  P  +  V EG+    +CK+  +   +L   W  +G
Sbjct: 244  RSRDSGDENEPIQERF-FRPHFLQAPGDL-TVQEGKLCRMDCKVSGLPTPDLS--WQLDG 299

Query: 1485 QPVTIGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            +PV      +  + + G  +L I  + + D+GIYTC A N                    
Sbjct: 300  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATN-------------------- 339

Query: 1544 RSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIP 1603
            R+ QN   LE +   ++  K              P+    L+N  + +G     E R++ 
Sbjct: 340  RAGQNSFSLELVVAAKEAHK-------------PPVFIEKLQNTGVADGYPVRLECRVLG 386

Query: 1604 VSDATLKVEWYHNNKPLK-SGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            V     ++ W   N+ L  S  R +   +N G++ L I     ED+G YT  A N  G
Sbjct: 387  VPPP--QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 442



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 65/241 (26%), Positives = 102/241 (42%), Gaps = 11/241 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN-D 3611
            E+G  P F        + E     F CR+    +   ++ WF +GK +   S   TI  D
Sbjct: 123  ENGMAPFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRD 180

Query: 3612 F-GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTE 3670
              G   L        D G YT  A N  G  + + +L V+        P+ PS       
Sbjct: 181  LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 240

Query: 3671 SIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRID 3730
               +  ++  + E I    E+   P F ++   ++ V EG     DC+V   G PT  + 
Sbjct: 241  PRSRSRDSGDENEPI---QERFFRPHF-LQAPGDLTVQEGKLCRMDCKVS--GLPTPDLS 294

Query: 3731 WFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
            W  +G+P    S    L  + G  +L I+ + +RDAG YTC ATN+ G  + + ++  +A
Sbjct: 295  WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAA 354

Query: 3790 K 3790
            K
Sbjct: 355  K 355



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 14/239 (5%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
            +P  ++ W+KDG+ I+  S   +I     G  SL+      +D G+YT+ A N  G    
Sbjct: 154  NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISC 213

Query: 857  TASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIK 916
            T  + V A +        P    ++ +                  + E   +P F     
Sbjct: 214  TGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEP----IQERFFRPHFLQAPG 269

Query: 917  DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GYVALTIKSVT 975
            D ++++EG     + ++   G  T  + W  DG+PV   S         G  +L I+ VT
Sbjct: 270  D-LTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 326

Query: 976  VHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTE 1034
              DAG YTC A N  GQ + S  L +  K+      + P  +EK+Q    A  Y  R E
Sbjct: 327  SRDAGIYTCIATNRAGQNSFSLELVVAAKE----AHKPPVFIEKLQNTGVADGYPVRLE 381



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 57/211 (27%), Positives = 91/211 (43%), Gaps = 11/211 (5%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA-RFHITFDF-GYVSLDIQHCVPED 2311
            +FEG    F C+V    +P  +I ++ +GK +   +  + I  D  G  SL       +D
Sbjct: 139  IFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 196

Query: 2312 AGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPV 2371
             G Y++ A N  G  +    + V A        + P G   +R   S       E  EP+
Sbjct: 197  DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDE-NEPI 255

Query: 2372 TRQ--RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-DSSRITKT 2428
              +  RP F Q   ++  +QEG+    DC++   G PT  + W  + K +  DS+     
Sbjct: 256  QERFFRPHFLQAPGDL-TVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLV 312

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             + G  S+ I  V   D G+Y C A+N  G+
Sbjct: 313  RENGVHSLIIEPVTSRDAGIYTCIATNRAGQ 343



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 59/238 (24%), Positives = 104/238 (43%), Gaps = 12/238 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DF-GFVALDIIHATSAD 1246
            + EG  +   CR+   G+P  ++ WF +G+ ++  S   T   D  G  +L    +T  D
Sbjct: 139  IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 196

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT 1306
             G YT+ A N  G    +  + V   +      ++      ++     +R +    E I 
Sbjct: 197  DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 256

Query: 1307 V-MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
                 P F +A  ++   EG    ++C++   G  T  + W  +GKP++     +     
Sbjct: 257  ERFFRPHFLQAPGDLTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLVRE 314

Query: 1366 DYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            + V +L +  V   D+G+YTC ATN+ G+   S  L V AK+      + P  +EK+Q
Sbjct: 315  NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE----AHKPPVFIEKLQ 368



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 58/224 (25%), Positives = 96/224 (42%), Gaps = 11/224 (4%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYV-SLDITHTYEEDSG 2844
            EG  + F C V  + +P  KI WF + K + P    Y    D     SL  T +  +D G
Sbjct: 141  EGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 198

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904
             YT  A N +G  + +G L     + +    + P+  +G   V +        G      
Sbjct: 199  NYTIMAANPQGRISCTGRLMV---QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPI 255

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK-LT 2963
               + +P + +    +  + EG++  ++ +V     PDL   W  +GK +   S  K L 
Sbjct: 256  QERFFRPHF-LQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKPVRPDSAHKMLV 312

Query: 2964 SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
             + G  +L +  V  RD+GIYTC A N+ G+   S  +   +K+
Sbjct: 313  RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 356



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 62/244 (25%), Positives = 105/244 (43%), Gaps = 16/244 (6%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN 963
            E+   P F+  +K    I EG    F  R+   G+   ++ W KDG+ +   S   T   
Sbjct: 123  ENGMAPFFEMKLK-HYKIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQR 179

Query: 964  F--GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
               G  +L   + T+ D G+YT  A N  G+ + +  L +          + P G   ++
Sbjct: 180  DLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVR 239

Query: 1022 YLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVE 1078
                 SR S    E ++    +P FL    G   + EG+    + +V   P  DL+    
Sbjct: 240  RPRSRSRDSGDENEPIQERFFRPHFL-QAPGDLTVQEGKLCRMDCKVSGLPTPDLS---- 294

Query: 1079 WYFNGKQIT--SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            W  +GK +   SA+++    + G  +L I  V + D+G+YT +A N AG+   S  + V 
Sbjct: 295  WQLDGKPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA 353

Query: 1137 TRSS 1140
             + +
Sbjct: 354  AKEA 357



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 64/247 (25%), Positives = 102/247 (41%), Gaps = 13/247 (5%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            LE+    ES +  +  ++P       P F   L++   I EG    F CR+   G+P  K
Sbjct: 103  LERSPVDESGDEVQYGDVPVE-NGMAPFFEMKLKHY-KIFEGMPVTFTCRV--AGNPKPK 158

Query: 2410 VEWFRNEKLIEDSS-RITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            + WF++ K I   S   T   D  G  S+  +    +D+G Y   A+N  G         
Sbjct: 159  IYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLM 218

Query: 2468 XXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE--PDRE-FEKPIFTQVLTGPSELWEGQ 2524
                       + P G   +++         +E  P +E F +P F Q   G   + EG+
Sbjct: 219  VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA-PGDLTVQEGK 277

Query: 2525 HAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THDFGFVTLDINSVVANDAGLYMC 2583
                + +V  +  P L   W ++G  ++  S  +    + G  +L I  V + DAG+Y C
Sbjct: 278  LCRMDCKVSGLPTPDL--SWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTC 335

Query: 2584 KAINRAG 2590
             A NRAG
Sbjct: 336  IATNRAG 342



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 70/295 (23%), Positives = 123/295 (41%), Gaps = 22/295 (7%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDF-GYV 2035
            P F   +K+ ++ EG PV    T     +P  ++ W+ +G+ +  +   +    D  G  
Sbjct: 128  PFFEMKLKHYKIFEGMPVTF--TCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 185

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA-----KSGLYLDTLDEQRLKKIQE 2090
            +L    +  +D G Y   A N  G    T  + V A     +S          R  + + 
Sbjct: 186  SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 245

Query: 2091 LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQ 2150
             +  +  +PI+E     RP FL A   L  ++EG     +C+V  +  P L+  W  +G+
Sbjct: 246  RDSGDENEPIQERF--FRPHFLQAPGDL-TVQEGKLCRMDCKVSGLPTPDLS--WQLDGK 300

Query: 2151 KIRAGHRYRT-THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
             +R    ++    + G  +L I    + D+G Y C ATN+ G+   +  L VA       
Sbjct: 301  PVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---- 356

Query: 2210 DTQHPNGLEKIRQL-EAQGHSTRIEVEEPKISPPR--FVTELRGTTHVFEGKTAH 2261
              + P  +EK++    A G+  R+E     + PP+  +  E    TH  +  + H
Sbjct: 357  AHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 411



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 72/271 (26%), Positives = 111/271 (40%), Gaps = 22/271 (8%)

Query: 2082 EQRLKKIQELEKYERPKPIEEE----QPGQRPV------FLTALTSLENLKEGDRAHFEC 2131
            EQRL  I E+E      P++E     Q G  PV      F         + EG    F C
Sbjct: 92   EQRL--ISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTC 149

Query: 2132 RVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNK 2189
            RV    +P   I WF +G++I      Y    D  G  +L    +  +D G Y   A N 
Sbjct: 150  RVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANP 207

Query: 2190 LGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE--EPKISPPRFVTE 2247
             G    T  L V          + P+G   +R+  ++   +  E E  + +   P F+ +
Sbjct: 208  QGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFL-Q 266

Query: 2248 LRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ-SAARFHITFDFGYVSLDIQH 2306
              G   V EGK    +C+V  +  P+L  +   +GK ++  +A   +  + G  SL I+ 
Sbjct: 267  APGDLTVQEGKLCRMDCKVSGLPTPDLSWQL--DGKPVRPDSAHKMLVRENGVHSLIIEP 324

Query: 2307 CVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
                DAG Y+  A N  G  + ++ + V AK
Sbjct: 325  VTSRDAGIYTCIATNRAGQNSFSLELVVAAK 355



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 51/219 (23%), Positives = 92/219 (42%), Gaps = 30/219 (13%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLR 324
           P   Q P +  +QEG   +   ++SG P P ++W  +G+ +   + H+++   N   +L 
Sbjct: 262 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 321

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +      D+G YT        CI T+      +   S+                 E  + 
Sbjct: 322 IEPVTSRDAGIYT--------CIATN-----RAGQNSF---------------SLELVVA 353

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
             E    P F++  Q+  V +G   R +CRV G P P++ W   +  +    +   +  +
Sbjct: 354 AKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 413

Query: 445 S-GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           + G   L+I   T  D+G  T  A+N++G  +   RL+V
Sbjct: 414 NHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 452



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 15/228 (6%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA---RLKSTFDF 2697
            AP F   LK Y K+ EG  V    +V     P  KI WFK+G  ++  +    ++   D 
Sbjct: 127  APFFEMKLKHY-KIFEGMPVTFTCRVAGNPKP--KIYWFKDGKQISPKSDHYTIQRDLD- 182

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL----LGESLHPDSLDRI 2753
            G  +L   +   DD G YT  A N  G    T  + ++  +         S HP  + R 
Sbjct: 183  GTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH-VRRP 241

Query: 2754 GALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN 2813
             +                    F+    ++  +EG     +C V  S  PT  + W  + 
Sbjct: 242  RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV--SGLPTPDLSWQLDG 299

Query: 2814 KPLPSGTRYKS-THDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
            KP+   + +K    +    SL I      D+GIYTC ATN  G  + S
Sbjct: 300  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS 347



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 52/219 (23%), Positives = 93/219 (42%), Gaps = 16/219 (7%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKN-RFTPI 4025
            V+    P F  +++       M  T F C++A  G+P  K+ WF +GK +  K+  +T  
Sbjct: 122  VENGMAPFFEMKLKHYKIFEGMPVT-FTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQ 178

Query: 4026 YDF-GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK---PGIVYDSQLPKHM 4081
             D  G  +++      +D G Y   A N  G       I  TG+     +    + P+  
Sbjct: 179  RDLDGTCSLHTTASTLDDDGNYTIMAANPQGR------ISCTGRLMVQAVNQRGRSPRSP 232

Query: 4082 KSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPR 4141
                 +R   +  + + ++     +    P F+  P  +TV+EG+  R  C+V+G P P 
Sbjct: 233  SGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPD 292

Query: 4142 VMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYDTG 4178
            + W L+G  +   S +K+    +G++   I      D G
Sbjct: 293  LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 331



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 68/276 (24%), Positives = 116/276 (42%), Gaps = 25/276 (9%)

Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESE 3845
            +C  +    +E +L +    E   E++ G   D P E  +    P F  ++K + + E  
Sbjct: 90   SCEQRLISEIEYRLERSPVDESGDEVQYG---DVPVENGMA---PFFEMKLKHYKIFEGM 143

Query: 3846 GVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYI 3903
             V F CRV    +PK +I W+++GK + P    Y    D+ G  SL       +D G Y 
Sbjct: 144  PVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 201

Query: 3904 CRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
              A N  G       ISC     +   NQ  RG  RS         +++  S    + D+
Sbjct: 202  IMAANPQGR------ISCTGRLMVQAVNQ--RG--RSPRSPSGHPHVRRPRSRSRDSGDE 251

Query: 3964 LYDVDKK-QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022
               + ++   P F+ Q     ++ E +  + +C+++  G P   + W  +GKP+   +  
Sbjct: 252  NEPIQERFFRPHFL-QAPGDLTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAH 308

Query: 4023 TP-IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057
               + + G  ++    V   D+G Y C ATN  G +
Sbjct: 309  KMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 344



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 2/123 (1%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            KPP+F +K+Q   V +    R E    G P P I W +EN  + +S D   +H  +   I
Sbjct: 359  KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 418

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L+I+    ED+  +   A+N  G   C+A L V  +  Q      P     +A      
Sbjct: 419  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAAL 478

Query: 4527 SGQ 4529
            S Q
Sbjct: 479  SDQ 481



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 55/243 (22%), Positives = 92/243 (37%), Gaps = 11/243 (4%)

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V    G  P F   +++ + + +G    F C V    +P  KI W+ +G+ +   +   T
Sbjct: 120  VPVENGMAPFFEMKLKHYK-IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYT 176

Query: 3201 VS-DF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT--RATINCYGKGGVYLESLQPDS 3256
            +  D  G   L    +   D G Y   A N  G      R  +    + G    S     
Sbjct: 177  IQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHP 236

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
              +     S     +  P       P F+    D+T + EG+    + ++  +  PDL  
Sbjct: 237  HVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLT-VQEGKLCRMDCKVSGLPTPDLS- 294

Query: 3317 EWFYNGKKL-PHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
             W  +GK + P         + G+  L I      ++G Y C+ATN+ G++S    L   
Sbjct: 295  -WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA 353

Query: 3376 SKE 3378
            +KE
Sbjct: 354  AKE 356



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
           PP   +K +N+ + +G   + + ++ G P P++ W K  + L +S     +   NH    
Sbjct: 360 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 419

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR 377
           L ++   K D+G YT+ A+N  G +  +  L V +      Q  + + +  +  R
Sbjct: 420 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASR 474



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/88 (27%), Positives = 41/88 (46%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+F +  +N   A G   + E ++ G P P + W ++   L         + +  G + 
Sbjct: 360 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 419

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS 158
           LLI+     D G YT +A+N+ G   C+
Sbjct: 420 LLIQGATKEDAGWYTVSAKNEAGIVSCT 447



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 12/123 (9%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS-RFKTYYD-FGF 1234
            PVF++ L N   V++G  + LECR+  +G P  ++ W     S+T  + R   + D  G+
Sbjct: 361  PVFIEKLQNTG-VADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGY 417

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTD-TQNEQAIEQIQLLED 1293
            + L I  AT  D G YTV A N  G      IV    R D+ T   Q  Q+ +  ++   
Sbjct: 418  ICLLIQGATKEDAGWYTVSAKNEAG------IVSCTARLDVYTQWHQQSQSTKPKKVRPS 471

Query: 1294 AAR 1296
            A+R
Sbjct: 472  ASR 474



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 5/101 (4%)

Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
           ++  + P FI  LQ+ G + +G     E ++  V  P  ++ W K+   +T S+   S+ 
Sbjct: 355 KEAHKPPVFIEKLQNTG-VADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMH 411

Query: 824 --NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             N GY+ L I     EDAG YTV A N+ G    TA + V
Sbjct: 412 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 452



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 51/224 (22%), Positives = 95/224 (42%), Gaps = 10/224 (4%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH-DF-GYVALDIIDLIAED 1513
            + EG  V F C++    +   K+ WFK+G+ ++       I  D  G  +L       +D
Sbjct: 139  IFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 196

Query: 1514 SGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEV 1573
             G YT  A N  G    + RL  ++     RS ++ +G   ++    RS+    D  + +
Sbjct: 197  DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR-DSGDENEPI 255

Query: 1574 TTQ--APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE-TN 1630
              +   P    +  ++ ++EG+    + ++  +   T  + W  + KP++  S       
Sbjct: 256  QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP--TPDLSWQLDGKPVRPDSAHKMLVR 313

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674
              G  +L I      D+G YTC A N  G+   S   +V +K++
Sbjct: 314  ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 357



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+ V EG+  +   +++    P + W  +G  + P++    ++ E     L+I      D
Sbjct: 270  DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 329

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             G +TC AT  AGQ   S +LVV +K
Sbjct: 330  AGIYTCIATNRAGQNSFSLELVVAAK 355



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA-TGS 3742
            E+ +  ++ + P   +E   N  V +G PV  +CRV  +G P  +I W         +  
Sbjct: 349  ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTD 406

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            RV    D  G+I L I      DAG YT  A N+ G  + TA++
Sbjct: 407  RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 450



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 4/114 (3%)

Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--F 691
           + PP FI  L++    +G  +  E R+  +G P  +I W K  +S+  S+   S+ +   
Sbjct: 358 HKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNH 415

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745
           GYI L +     +D+G YT  A +  G+    A L V  +   +  S  P+ ++
Sbjct: 416 GYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVR 469



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR-NEKLIEDSSRITKTHD-FGY 2433
            PVF + LQN   + +G     +CR++ V  P  ++ W + NE L   + R++   D  GY
Sbjct: 361  PVFIEKLQNT-GVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 417

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
            + + I     ED G Y   A N  G
Sbjct: 418  ICLLIQGATKEDAGWYTVSAKNEAG 442



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 4/104 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGYV 1768
            PVF   +++  VA+      E R++ V  P+  + W +    +  S    +MH  + GY+
Sbjct: 361  PVFIEKLQNTGVADGYPVRLECRVLGVPPPQ--IFWKKENESLTHSTDRVSMHQDNHGYI 418

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
             L ++    ED+G YT  A NE G    ++ L V ++   Q +S
Sbjct: 419  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQS 462



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE- 4785
            L+   ++EG P  F  ++    KP I W ++G  I    D   I    +    +  T   
Sbjct: 134  LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 193

Query: 4786 -EDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +D G +T  A    G++  + +L+V++
Sbjct: 194  LDDDGNYTIMAANPQGRISCTGRLMVQA 221



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 3/109 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGY 2299
            PP F+ +L+ T  V +G     EC+V  V  P +  +   N     S  R  +  D  GY
Sbjct: 360  PPVFIEKLQNTG-VADGYPVRLECRVLGVPPPQIFWK-KENESLTHSTDRVSMHQDNHGY 417

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPE 2348
            + L IQ    EDAG Y+V A N  G  +    + V  +    S+S +P+
Sbjct: 418  ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPK 466



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 58  RQPITAGRP-GEPSPPIFEQIFK--------NARFAQGGNAKFEGKLRGNPTPVVSWTRK 108
           R+P +  R  G+ + PI E+ F+        +    +G   + + K+ G PTP +SW   
Sbjct: 239 RRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 298

Query: 109 KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
             P+   + + M   E  G  SL+I+ +   D G YTC A N+ G+
Sbjct: 299 GKPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQ 343



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 4/108 (3%)

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD---FQIH 4460
            PV+    P F  K++  ++FE     F     G P P I W+++   I    D    Q  
Sbjct: 121  PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 180

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
               T S+       ++D   +  +A N  G   C+  L+V+   ++GR
Sbjct: 181  LDGTCSLHTTAST-LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR 227



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 10/138 (7%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF- 962
            E+ + P F   +++   + +G     E R+  +G    ++ W K+   +  S+   +   
Sbjct: 356  EAHKPPVFIEKLQNT-GVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQ 412

Query: 963  -NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             N GY+ L I+  T  DAG YT  A N  G  + +A L + T+    ++S  P   +K++
Sbjct: 413  DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP---KKVR 469

Query: 1022 YLEDASRYSKRTEEEVKI 1039
                ASRY+  +++ + I
Sbjct: 470  --PSASRYAALSDQGLDI 485



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 5/98 (5%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHD-FGY 1100
            P F+  L+ T  + +G     E RV         + W    + +T S +R+  + D  GY
Sbjct: 361  PVFIEKLQNTG-VADGYPVRLECRVLGVPP--PQIFWKKENESLTHSTDRVSMHQDNHGY 417

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            + L I     ED+G YTV A+N AG    +A + V T+
Sbjct: 418  ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQ 455



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/107 (24%), Positives = 40/107 (37%)

Query: 52  VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
           V+ SGD              P FE   K+ +  +G    F  ++ GNP P + W +    
Sbjct: 108 VDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 167

Query: 112 LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
           +   + +     +  G  SL        D+G YT  A N  G   C+
Sbjct: 168 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCT 214



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVS 2832
            VFI  L N    +G  +  EC V     P  +I W   N+ L   T   S H  +  Y+ 
Sbjct: 362  VFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYIC 419

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I    +ED+G YT  A N  G  + +  L
Sbjct: 420  LLIQGATKEDAGWYTVSAKNEAGIVSCTARL 450



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 4/110 (3%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S +++ +    E+  PP F     +  +++      ECR++ V     ++ W    + L 
Sbjct: 345  SFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLT 402

Query: 3602 TGS-RVKTIND-FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              + RV    D  G++ L I G  + DAG YT  A N  G  + + +L V
Sbjct: 403  HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 452



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/57 (31%), Positives = 27/57 (47%)

Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            E VV   +A  PPVF+       V +G   R  CRV G P P++ W     ++ + +
Sbjct: 349  ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 405



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 10/162 (6%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFRTF 3472
            +E  K PVF   L N   + +G     E R+     P  ++ W    +SL   + R    
Sbjct: 355  KEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMH 411

Query: 3473 CD-FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT 3531
             D  G++ L I     ED+G Y   A N  G    TA + V  + +   +S  PK +  +
Sbjct: 412  QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPS 471

Query: 3532 IDKIAALEGYSGTVD-TLTPEAESGNPPEFTTTPSDLILSEN 3572
              + AAL      +     PEA   NP   T   + L+ SE+
Sbjct: 472  ASRYAALSDQGLDIKAAFQPEA---NPSHLTLNTA-LVESED 509



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 5/101 (4%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTSND- 1898
            ++ P FI +L   T +++G     ECR+   P P  ++ W   N  +  S  R     D 
Sbjct: 358  HKPPVFIEKLQN-TGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDN 414

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
             G+  L I     ED+G YT  A N  G    + RL+V ++
Sbjct: 415  HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQ 455



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYD-FGYV 2035
            P F + ++N  V +G+PV LE  +  V  P  ++ W      +     R     D  GY+
Sbjct: 361  PVFIEKLQNTGVADGYPVRLECRVLGV--PPPQIFWKKENESLTHSTDRVSMHQDNHGYI 418

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             L I  A  ED G Y   A N  G    T+ + V
Sbjct: 419  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 452



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTVYD-MGF 3886
            PP FI ++++  V +   VR ECRV     P  +I W + N  L  S  R     D  G+
Sbjct: 360  PPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 417

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
            + L I     ED+G Y   A N+ G
Sbjct: 418  ICLLIQGATKEDAGWYTVSAKNEAG 442



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 13/139 (9%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD---Y 1367
            P F   L N    +G  V LECR+  +G    ++ W    + + T    R +   D   Y
Sbjct: 361  PVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESL-THSTDRVSMHQDNHGY 417

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
            + L +     ED+G YT  A N+ G  + SC  R+        +SQ     +K++     
Sbjct: 418  ICLLIQGATKEDAGWYTVSAKNEAG--IVSCTARLDVYTQWHQQSQSTKP-KKVR--PSA 472

Query: 1428 SRYKKTDIIDESVTIKPRF 1446
            SRY    + D+ + IK  F
Sbjct: 473  SRY--AALSDQGLDIKAAF 489


>AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein.
          Length = 1106

 Score =  206 bits (504), Expect = 1e-51
 Identities = 118/375 (31%), Positives = 198/375 (52%), Gaps = 13/375 (3%)

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
            + ++  ++KV + E RL+ E+ +R  + +  V ES  ++    D  +     P    K +
Sbjct: 728  EETANQEYKVSSCEQRLISEIEYR--LERSPVDESGDEVQYG-DVPVENGMAPFFEMKLK 784

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS-- 331
            + K+ EG    F  +++GNP+P++ WFK+G+++   + H  I      T  +  T  +  
Sbjct: 785  HYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLD 844

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTE---SYVQDQRSQYITDTQQRETE---ERIEI 385
            D G+YT++A NP G I  +G L V++  +   S        ++   + R  +   E   I
Sbjct: 845  DDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPI 904

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
             E+   P F++   D  V EGK+ R DC+V+G P P+++W ++ + +R D  HK+LV E+
Sbjct: 905  QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
            G H+L+I  VT  D+G+ TC+A N++G+ +F   L V  KE    P F+E+     V +G
Sbjct: 965  GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 1024

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDG-GASTLDIPRAKASDAAWYQC 563
             PV L  R +G P P+I W+K+   +  + + + +H D  G   L I  A   DA WY  
Sbjct: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084

Query: 564  TAQNVAGSTATRARL 578
            +A+N AG  +  ARL
Sbjct: 1085 SAKNEAGIVSCTARL 1099



 Score =  104 bits (250), Expect = 7e-21
 Identities = 79/325 (24%), Positives = 137/325 (42%), Gaps = 28/325 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTL 4571
            P F +  ++  +  G  V    +V G     +YW K+GK++ P   +  ++ D  GT +L
Sbjct: 777  PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-----------KPQTKAA- 4619
                +   D G Y  +A N  G   C    +V     + +            +P++++  
Sbjct: 837  HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896

Query: 4620 ----NAP-------PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP-SK 4667
                N P       P  ++   D  V EG+     CK+ G P P + W    K ++P S 
Sbjct: 897  SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +  + R    ++L I      D G Y C+A N AG+ + + +L V   +       +  L
Sbjct: 957  HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYE 4785
            ++  V +G P + + ++     P I W +E   +  + D   +H+ N+    LLI    +
Sbjct: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
            ED G +T  A   AG V  +A+L V
Sbjct: 1077 EDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 81/312 (25%), Positives = 136/312 (43%), Gaps = 21/312 (6%)

Query: 2940 DPDLKIEWYFNGKVLEQGS-RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +P  KI W+ +GK +   S  + +  D  G  +L        D G YT  A N +G    
Sbjct: 803  NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISC 862

Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQ-QPDDDTGRPPEFTTVFKD 3056
            +  +   + +   +R + P+   G   ++      R    + +P  +    P F     D
Sbjct: 863  TGRLMVQAVN---QRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGD 919

Query: 3057 IVDISEGQIAHYEASL--IPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILG 3112
            +  + EG++   +  +  +PT D S    W  +GK +  +++H++  V   G+  L I  
Sbjct: 920  LT-VQEGKLCRMDCKVSGLPTPDLS----WQLDGKPVRPDSAHKM-LVRENGVHSLIIEP 973

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172
              + D+G Y+C ATN+ GQ   S++L    K   + P F   +QN  G+ DG     EC 
Sbjct: 974  VTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN-TGVADGYPVRLECR 1032

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHST-RIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
            V+ V  P  +I W    + + HST R+    D  G++ L I      D+G Y   A N+ 
Sbjct: 1033 VLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090

Query: 3231 GEDFTRATINCY 3242
            G     A ++ Y
Sbjct: 1091 GIVSCTARLDVY 1102



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 63/236 (26%), Positives = 101/236 (42%), Gaps = 9/236 (3%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA-SNRLTTMHDF-GY 1767
            AP F M +K  ++ E     F  R+   G+PK ++ W ++G  I   S+  T   D  G 
Sbjct: 776  APFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+      +D G YT  A N  G    +  L VQ+        +  S    +++    
Sbjct: 834  CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 893

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887
            SR    E+  +          Q  G   + EG+    +C++   P P++   W  +GK +
Sbjct: 894  SRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKPV 951

Query: 1888 Q--SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            +  S H+     + G  +L I  V   D+G YTC A N  GQ   S+ L V +KE+
Sbjct: 952  RPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 1006



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 71/276 (25%), Positives = 113/276 (40%), Gaps = 34/276 (12%)

Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG-ASTL 548
           AP+F+++  +  V EG  V L  R  G PTPR+ W  +G  +   P+++IH +GG   TL
Sbjct: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329

Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRL-------HLPRPTKV 601
            I  A   D   Y C A N +GS  T A ++           + L        +P+  K 
Sbjct: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKK 389

Query: 602 XXXXXXXXXXXXYLRHVERA--RPYIPPGEE--------------DRVYPPPQFIVPLKS 645
                           V  A  +P   P ++                 Y PP F   L++
Sbjct: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQN 449

Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL---DMLSLN 702
               EG  +  E R+   G P ++++W + G  I+ S  F  + +    +    ++ +L 
Sbjct: 450 TAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507

Query: 703 I-----QDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
           I     +D+G +TC A +  G A + A L VT   T
Sbjct: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 72/247 (29%), Positives = 105/247 (42%), Gaps = 15/247 (6%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            V  E G AP F + L + + + EG    F  R+    +P  K+ W+ +GK +   S   T
Sbjct: 769  VPVENGMAPFFEMKLKHYK-IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYT 825

Query: 3472 FC-DF-GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGME 3529
               D  G   L  + +  +D G Y   A N  G    T  + VQ         + P G  
Sbjct: 826  IQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG-H 884

Query: 3530 GTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDS 3587
              + +  +    SG  D   P  E    P F   P DL + E      +C++  +P  D 
Sbjct: 885  PHVRRPRSRSRDSG--DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL 942

Query: 3588 SMRVEWFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            S    W  +GKP+   S  K  + + G   L I  V  RDAG+YTC ATNR G+ + S +
Sbjct: 943  S----WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLE 998

Query: 3647 LQVKGRQ 3653
            L V  ++
Sbjct: 999  LVVAAKE 1005



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 11/234 (4%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--FGYI 694
            P F + LK     EG  + F  R+   G+P  KI W K+G+ I   S   +I R   G  
Sbjct: 777  PFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            SL   +  + D G YT  A +  G       L V       R+ + P    ++++    S
Sbjct: 835  SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 894

Query: 755  K--YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
            +      E I+E+   RP F++   DL  +QEG+    + +++ +  PT  + W  DG+P
Sbjct: 895  RDSGDENEPIQERFF-RPHFLQAPGDL-TVQEGKLCRMDCKVSGL--PTPDLSWQLDGKP 950

Query: 813  ITA-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            +   S+    +   G  SL I  + + DAG YT  A N+ G+   +  + VAA+
Sbjct: 951  VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 55/192 (28%), Positives = 80/192 (41%), Gaps = 8/192 (4%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILI 4469
            P F +      V E +  R + +  G P P + W  +  P++ +S    +   +    LI
Sbjct: 911  PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I  V   D+ ++  +A NR G    S  LVV  K         PP F    QN  V  G 
Sbjct: 971  IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-----PPVFIEKLQNTGVADGY 1025

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYECV 4587
             VRL+ +V G  P  ++W K  + +        + +D  G   LLI  A  +D+G Y   
Sbjct: 1026 PVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVS 1085

Query: 4588 AINSAGEARCDA 4599
            A N AG   C A
Sbjct: 1086 AKNEAGIVSCTA 1097



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 68/225 (30%), Positives = 100/225 (44%), Gaps = 14/225 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN-DF-GF 3752
            P F +++K +  + EG PV F CRV   G+P  +I WF +G+  +  S  +T+  D  G 
Sbjct: 777  PFFEMKLK-HYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
             +L        D G YT  A N  G  + T ++   A   +    + P+  SG       
Sbjct: 834  CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQA---VNQRGRSPRSPSGHPHVRRP 890

Query: 3813 RGRISDAPKE-EPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
            R R  D+  E EPI      P F+      TV+E +  R +C+V     P L   W  +G
Sbjct: 891  RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDG 948

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            K + P       V + G  SL I  V + D+G Y C A N  G++
Sbjct: 949  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 993



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 5/146 (3%)

Query: 4579 QDSGKYECVAINSAGEARC--DAECVVSLPATKDKPKPQTKAA-NAPPEIIEPLKDKIVA 4635
            +D G+ E   + S G   C  D + +      K  P+P +     A P  I+ L+ + VA
Sbjct: 225  EDQGEMER-EVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVA 283

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM-SRTADEYTLRISEAFPEDEGDYK 4694
            EG  +   C++ G P P V+W+   K +  +   Q+     D +TL I+EAF +D G Y 
Sbjct: 284  EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYT 343

Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQADN 4720
            C+A N +G  T +A++ +      D+
Sbjct: 344  CLATNPSGSDTTSAEVFIEGASSTDS 369



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 38/106 (35%), Positives = 55/106 (51%), Gaps = 8/106 (7%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIR------NKILE 4564
            PP FT   QN  V  GQ+V L+ +V G  P+ V W + G ++Q  PD R          E
Sbjct: 440  PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499

Query: 4565 EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
             +   TL+I E +P+D+G + C A N  G A   A+ VV+   T++
Sbjct: 500  PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTEN 545



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 90/358 (25%), Positives = 144/358 (40%), Gaps = 50/358 (13%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KTGHRFRPAYEFDY 1367
            AP F   L + +  EG  V   CR+   G+   ++ WF +GK I  K+ H +    + D 
Sbjct: 776  APFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDH-YTIQRDLDG 832

Query: 1368 V-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426
              +L   +   +D G YT  A N  G    +  L V A        + PSG   ++    
Sbjct: 833  TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 892

Query: 1427 TSRYK--KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484
             SR    + + I E    +P F+  P  +  V EG+    +CK+  +   +L   W  +G
Sbjct: 893  RSRDSGDENEPIQERF-FRPHFLQAPGDL-TVQEGKLCRMDCKVSGLPTPDLS--WQLDG 948

Query: 1485 QPVTIGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            +PV      +  + + G  +L I  + + D+GIYTC A N                    
Sbjct: 949  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATN-------------------- 988

Query: 1544 RSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIP 1603
            R+ QN   LE +   ++  K              P+    L+N  + +G     E R++ 
Sbjct: 989  RAGQNSFSLELVVAAKEAHK-------------PPVFIEKLQNTGVADGYPVRLECRVLG 1035

Query: 1604 VSDATLKVEWYHNNKPLK-SGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            V     ++ W   N+ L  S  R +   +N G++ L I     ED+G YT  A N  G
Sbjct: 1036 VPPP--QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 65/241 (26%), Positives = 102/241 (42%), Gaps = 11/241 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN-D 3611
            E+G  P F        + E     F CR+    +   ++ WF +GK +   S   TI  D
Sbjct: 772  ENGMAPFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRD 829

Query: 3612 F-GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTE 3670
              G   L        D G YT  A N  G  + + +L V+        P+ PS       
Sbjct: 830  LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889

Query: 3671 SIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRID 3730
               +  ++  + E I    E+   P F ++   ++ V EG     DC+V   G PT  + 
Sbjct: 890  PRSRSRDSGDENEPI---QERFFRPHF-LQAPGDLTVQEGKLCRMDCKVS--GLPTPDLS 943

Query: 3731 WFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
            W  +G+P    S    L  + G  +L I+ + +RDAG YTC ATN+ G  + + ++  +A
Sbjct: 944  WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAA 1003

Query: 3790 K 3790
            K
Sbjct: 1004 K 1004



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 14/239 (5%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
            +P  ++ W+KDG+ I+  S   +I     G  SL+      +D G+YT+ A N  G    
Sbjct: 803  NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISC 862

Query: 857  TASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIK 916
            T  + V A +        P    ++ +                  + E   +P F     
Sbjct: 863  TGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEP----IQERFFRPHFLQAPG 918

Query: 917  DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GYVALTIKSVT 975
            D ++++EG     + ++   G  T  + W  DG+PV   S         G  +L I+ VT
Sbjct: 919  D-LTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975

Query: 976  VHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTE 1034
              DAG YTC A N  GQ + S  L +  K+      + P  +EK+Q    A  Y  R E
Sbjct: 976  SRDAGIYTCIATNRAGQNSFSLELVVAAKE----AHKPPVFIEKLQNTGVADGYPVRLE 1030



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 57/211 (27%), Positives = 91/211 (43%), Gaps = 11/211 (5%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA-RFHITFDF-GYVSLDIQHCVPED 2311
            +FEG    F C+V    +P  +I ++ +GK +   +  + I  D  G  SL       +D
Sbjct: 788  IFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 845

Query: 2312 AGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPV 2371
             G Y++ A N  G  +    + V A        + P G   +R   S       E  EP+
Sbjct: 846  DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDE-NEPI 904

Query: 2372 TRQ--RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-DSSRITKT 2428
              +  RP F Q   ++  +QEG+    DC++   G PT  + W  + K +  DS+     
Sbjct: 905  QERFFRPHFLQAPGDL-TVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLV 961

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             + G  S+ I  V   D G+Y C A+N  G+
Sbjct: 962  RENGVHSLIIEPVTSRDAGIYTCIATNRAGQ 992



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 59/238 (24%), Positives = 104/238 (43%), Gaps = 12/238 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DF-GFVALDIIHATSAD 1246
            + EG  +   CR+   G+P  ++ WF +G+ ++  S   T   D  G  +L    +T  D
Sbjct: 788  IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 845

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT 1306
             G YT+ A N  G    +  + V   +      ++      ++     +R +    E I 
Sbjct: 846  DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 905

Query: 1307 V-MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
                 P F +A  ++   EG    ++C++   G  T  + W  +GKP++     +     
Sbjct: 906  ERFFRPHFLQAPGDLTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLVRE 963

Query: 1366 DYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            + V +L +  V   D+G+YTC ATN+ G+   S  L V AK+      + P  +EK+Q
Sbjct: 964  NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE----AHKPPVFIEKLQ 1017



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 58/224 (25%), Positives = 96/224 (42%), Gaps = 11/224 (4%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYV-SLDITHTYEEDSG 2844
            EG  + F C V  + +P  KI WF + K + P    Y    D     SL  T +  +D G
Sbjct: 790  EGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904
             YT  A N +G  + +G L     + +    + P+  +G   V +        G      
Sbjct: 848  NYTIMAANPQGRISCTGRLMV---QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPI 904

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK-LT 2963
               + +P + +    +  + EG++  ++ +V     PDL   W  +GK +   S  K L 
Sbjct: 905  QERFFRPHF-LQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKPVRPDSAHKMLV 961

Query: 2964 SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
             + G  +L +  V  RD+GIYTC A N+ G+   S  +   +K+
Sbjct: 962  RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 5/103 (4%)

Query: 4714 QPDQADNLPA----LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            QP  A + PA    +  LR   V EG     + ++T    P ++W  EG  +  TPD Q+
Sbjct: 260  QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319

Query: 4770 IHEGNNA-VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              EG +   L+I   +E+DTG +TC AT  +G   TSA++ ++
Sbjct: 320  HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 35/89 (39%), Positives = 48/89 (53%), Gaps = 3/89 (3%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE-FDYV 1368
            AP+F + L + E  EG+ V+LECR+   G+ T RV WFC GK +      +   E  D  
Sbjct: 270  APRFIQKLRSQEVAEGSRVYLECRV--TGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             L +   + +D+G YTC ATN  G   TS
Sbjct: 328  TLIIAEAFEDDTGRYTCLATNPSGSDTTS 356



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 39/131 (29%), Positives = 64/131 (48%), Gaps = 7/131 (5%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLR 324
           P+  QK R+ ++ EG+    + +++GNP PRV WF  G+ L N+   +I        TL 
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTS------GYLAVESPTESYVQDQRSQYITDTQQRE 378
           +    + D+G YT LA NP+G   TS      G  + +S +ES     R+  +   Q++ 
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390

Query: 379 TEERIEISEKA 389
           T   + I   +
Sbjct: 391 TSVSLTIGSSS 401



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 62/244 (25%), Positives = 105/244 (43%), Gaps = 16/244 (6%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN 963
            E+   P F+  +K    I EG    F  R+   G+   ++ W KDG+ +   S   T   
Sbjct: 772  ENGMAPFFEMKLK-HYKIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQR 828

Query: 964  F--GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
               G  +L   + T+ D G+YT  A N  G+ + +  L +          + P G   ++
Sbjct: 829  DLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVR 888

Query: 1022 YLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVE 1078
                 SR S    E ++    +P FL    G   + EG+    + +V   P  DL+    
Sbjct: 889  RPRSRSRDSGDENEPIQERFFRPHFL-QAPGDLTVQEGKLCRMDCKVSGLPTPDLS---- 943

Query: 1079 WYFNGKQIT--SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            W  +GK +   SA+++    + G  +L I  V + D+G+YT +A N AG+   S  + V 
Sbjct: 944  WQLDGKPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA 1002

Query: 1137 TRSS 1140
             + +
Sbjct: 1003 AKEA 1006



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 73/298 (24%), Positives = 120/298 (40%), Gaps = 34/298 (11%)

Query: 69  PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
           P+ P F Q  ++   A+G     E ++ GNPTP V W  +   L   N   ++ + + GD
Sbjct: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL--HNTPDIQIHCEGGD 325

Query: 129 V-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVE 187
           + +L+I +    D G YTC A N  G    S  +  EG                 SE++ 
Sbjct: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSD----------SESLA 375

Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247
            K+    G   +  ++T  V+ T G   SS+    V T   + L       S+  + V  
Sbjct: 376 FKS--RAGAMPQAQKKTTSVSLTIG---SSSPKTGVTTAVIQPL-------SVPVQQV-H 422

Query: 248 SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307
           S        D +     PP   ++ +N+ + EG     + ++ G P  +V WF+ G  + 
Sbjct: 423 SPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQ 482

Query: 308 NSNKHEIITTHNHT--------TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
           +S    I+     +        TL +  T   D+G +T  A N  G   ++  L V S
Sbjct: 483 DSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 28/82 (34%), Positives = 44/82 (53%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP+F++  + ++V EG     +CRVTG P P V WF   +++ +  + +I       H L
Sbjct: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329

Query: 451 MITNVTLSDSGVVTCVARNKSG 472
           +I      D+G  TC+A N SG
Sbjct: 330 IIAEAFEDDTGRYTCLATNPSG 351



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 8/106 (7%)

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR-- 4673
            T  A  PP   + L++  VAEGQ +   C++ G P   VQW++    I+ S  F++ +  
Sbjct: 434  TTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKK 493

Query: 4674 ---TADE---YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
               TA+     TL I+E FPED G + C A N  G  T  A+L VT
Sbjct: 494  PRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 64/247 (25%), Positives = 102/247 (41%), Gaps = 13/247 (5%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            LE+    ES +  +  ++P       P F   L++   I EG    F CR+   G+P  K
Sbjct: 752  LERSPVDESGDEVQYGDVPVE-NGMAPFFEMKLKHY-KIFEGMPVTFTCRV--AGNPKPK 807

Query: 2410 VEWFRNEKLIEDSS-RITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            + WF++ K I   S   T   D  G  S+  +    +D+G Y   A+N  G         
Sbjct: 808  IYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLM 867

Query: 2468 XXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE--PDRE-FEKPIFTQVLTGPSELWEGQ 2524
                       + P G   +++         +E  P +E F +P F Q   G   + EG+
Sbjct: 868  VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA-PGDLTVQEGK 926

Query: 2525 HAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THDFGFVTLDINSVVANDAGLYMC 2583
                + +V  +  P L   W ++G  ++  S  +    + G  +L I  V + DAG+Y C
Sbjct: 927  LCRMDCKVSGLPTPDL--SWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTC 984

Query: 2584 KAINRAG 2590
             A NRAG
Sbjct: 985  IATNRAG 991



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 3/103 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV-A 2036
            P+F + +++ EV EG  V+LE  +T   +PT RV W+C G+ +      +   + G +  
Sbjct: 271  PRFIQKLRSQEVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDT 2079
            L I  A+ +DTG Y C ATN  G   T++ V ++  S    D+
Sbjct: 329  LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS 371



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 70/295 (23%), Positives = 123/295 (41%), Gaps = 22/295 (7%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDF-GYV 2035
            P F   +K+ ++ EG PV    T     +P  ++ W+ +G+ +  +   +    D  G  
Sbjct: 777  PFFEMKLKHYKIFEGMPVTF--TCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA-----KSGLYLDTLDEQRLKKIQE 2090
            +L    +  +D G Y   A N  G    T  + V A     +S          R  + + 
Sbjct: 835  SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 894

Query: 2091 LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQ 2150
             +  +  +PI+E     RP FL A   L  ++EG     +C+V  +  P L+  W  +G+
Sbjct: 895  RDSGDENEPIQERF--FRPHFLQAPGDL-TVQEGKLCRMDCKVSGLPTPDLS--WQLDGK 949

Query: 2151 KIRAGHRYRT-THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
             +R    ++    + G  +L I    + D+G Y C ATN+ G+   +  L VA       
Sbjct: 950  PVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---- 1005

Query: 2210 DTQHPNGLEKIRQL-EAQGHSTRIEVEEPKISPPR--FVTELRGTTHVFEGKTAH 2261
              + P  +EK++    A G+  R+E     + PP+  +  E    TH  +  + H
Sbjct: 1006 AHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 72/271 (26%), Positives = 111/271 (40%), Gaps = 22/271 (8%)

Query: 2082 EQRLKKIQELEKYERPKPIEEE----QPGQRPV------FLTALTSLENLKEGDRAHFEC 2131
            EQRL  I E+E      P++E     Q G  PV      F         + EG    F C
Sbjct: 741  EQRL--ISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTC 798

Query: 2132 RVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNK 2189
            RV    +P   I WF +G++I      Y    D  G  +L    +  +D G Y   A N 
Sbjct: 799  RVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANP 856

Query: 2190 LGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE--EPKISPPRFVTE 2247
             G    T  L V          + P+G   +R+  ++   +  E E  + +   P F+ +
Sbjct: 857  QGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFL-Q 915

Query: 2248 LRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ-SAARFHITFDFGYVSLDIQH 2306
              G   V EGK    +C+V  +  P+L  +   +GK ++  +A   +  + G  SL I+ 
Sbjct: 916  APGDLTVQEGKLCRMDCKVSGLPTPDLSWQL--DGKPVRPDSAHKMLVRENGVHSLIIEP 973

Query: 2307 CVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
                DAG Y+  A N  G  + ++ + V AK
Sbjct: 974  VTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 8/99 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS--- 4466
            PP+FTK++Q   V E +    E    G P   ++W+R+   I++SPDF+I     +S   
Sbjct: 440  PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499

Query: 4467 -----ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
                  L+I + F ED+ +F   A N  G+A  +A LVV
Sbjct: 500  PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG 3751
            P  PRF  +++   +V EG  V+ +CRV   G+PT R+ WF  G+       +    + G
Sbjct: 268  PAAPRFIQKLRSQ-EVAEGSRVYLECRV--TGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324

Query: 3752 FI-ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             +  L I   +  D G YTC ATN  GS TT+A++
Sbjct: 325  DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV 359



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 41/126 (32%), Positives = 63/126 (50%), Gaps = 4/126 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV- 1235
            P F+Q L +   V+EG  ++LECR+   G+PT RV WF  G+ +      + + + G + 
Sbjct: 271  PRFIQKLRSQE-VAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
             L I  A   DTG YT  A N  GS  TSA V +   S   +D+++     +   +  A 
Sbjct: 328  TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387

Query: 1296 RRTKQV 1301
            ++T  V
Sbjct: 388  KKTTSV 393



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 36/118 (30%), Positives = 59/118 (50%), Gaps = 3/118 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SLD 2834
            FI  L +    EG  ++ EC V  + +PT ++ WF   K L +    +   +   + +L 
Sbjct: 273  FIQKLRSQEVAEGSRVYLECRV--TGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE 2892
            I   +E+D+G YTC ATN  GS TTS  +   G  +   D++    K+   A+ QA++
Sbjct: 331  IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQK 388



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 51/219 (23%), Positives = 92/219 (42%), Gaps = 30/219 (13%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLR 324
            P   Q P +  +QEG   +   ++SG P P ++W  +G+ +   + H+++   N   +L 
Sbjct: 911  PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +      D+G YT        CI T+      +   S+                 E  + 
Sbjct: 971  IEPVTSRDAGIYT--------CIATN-----RAGQNSF---------------SLELVVA 1002

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
              E    P F++  Q+  V +G   R +CRV G P P++ W   +  +    +   +  +
Sbjct: 1003 AKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 1062

Query: 445  S-GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            + G   L+I   T  D+G  T  A+N++G  +   RL+V
Sbjct: 1063 NHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 4/106 (3%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFG-F 1901
            APRFI +L    +++EG   + ECR+   P P  RV W+  GK L +    +   + G  
Sbjct: 270  APRFIQKLRSQ-EVAEGSRVYLECRVTGNPTP--RVRWFCEGKELHNTPDIQIHCEGGDL 326

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
              L I   + +D+G YTC A N  G   +S  + ++   S   DS+
Sbjct: 327  HTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 46/153 (30%), Positives = 67/153 (43%), Gaps = 13/153 (8%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL--------TTM 1762
            PVFT  +++  VAE Q    E R+   G P L+V+W R G  I+ S           +T 
Sbjct: 441  PVFTKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS--KASLQLESQHESALQK 1820
                   L +    PED+G +TC A N+ G A +++ L V S    +   ES  ES    
Sbjct: 499  EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDH 558

Query: 1821 IQQLEDSSRYQRREDVEVAVNQAPRFITQLNGP 1853
             Q             +E+A ++ P  I Q+N P
Sbjct: 559  FQHFPPPPPILETSSLELA-SKKPSEIQQVNNP 590



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 10/100 (10%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR--------PA 1362
            P F++ L N    EG  V LECR++  G   ++V+WF  G  I+    FR         A
Sbjct: 441  PVFTKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498

Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
               +   L +   +PED+G++TC A N  G A ++  L V
Sbjct: 499  EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 15/228 (6%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA---RLKSTFDF 2697
            AP F   LK Y K+ EG  V    +V     P  KI WFK+G  ++  +    ++   D 
Sbjct: 776  APFFEMKLKHY-KIFEGMPVTFTCRVAGNPKP--KIYWFKDGKQISPKSDHYTIQRDLD- 831

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL----LGESLHPDSLDRI 2753
            G  +L   +   DD G YT  A N  G    T  + ++  +         S HP  + R 
Sbjct: 832  GTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH-VRRP 890

Query: 2754 GALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN 2813
             +                    F+    ++  +EG     +C V  S  PT  + W  + 
Sbjct: 891  RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV--SGLPTPDLSWQLDG 948

Query: 2814 KPLPSGTRYKS-THDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
            KP+   + +K    +    SL I      D+GIYTC ATN  G  + S
Sbjct: 949  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS 996



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 3/99 (3%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTYTL 4571
            P F    ++  V  G  V L+ +VTG     V W   GK++   PDI+    E    +TL
Sbjct: 271  PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC-EGGDLHTL 329

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
            +I EA+  D+G+Y C+A N +G     AE  +   ++ D
Sbjct: 330  IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD 368



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 1/92 (1%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-TFSTKSILI 4469
            P F +K++   V E  +   E    G P P ++W+ E   + N+PD QIH        LI
Sbjct: 271  PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I + F +D+  +  +A N  G+   SA + +E
Sbjct: 331  IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 52/219 (23%), Positives = 93/219 (42%), Gaps = 16/219 (7%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKN-RFTPI 4025
            V+    P F  +++       M  T F C++A  G+P  K+ WF +GK +  K+  +T  
Sbjct: 771  VENGMAPFFEMKLKHYKIFEGMPVT-FTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQ 827

Query: 4026 YDF-GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK---PGIVYDSQLPKHM 4081
             D  G  +++      +D G Y   A N  G       I  TG+     +    + P+  
Sbjct: 828  RDLDGTCSLHTTASTLDDDGNYTIMAANPQGR------ISCTGRLMVQAVNQRGRSPRSP 881

Query: 4082 KSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPR 4141
                 +R   +  + + ++     +    P F+  P  +TV+EG+  R  C+V+G P P 
Sbjct: 882  SGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPD 941

Query: 4142 VMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYDTG 4178
            + W L+G  +   S +K+    +G++   I      D G
Sbjct: 942  LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 980



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 4/104 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV- 1101
            PRF+  L+ + ++ EG   + E RV    + T  V W+  GK++ +   IQ + + G + 
Sbjct: 271  PRFIQKLR-SQEVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSS 1145
             L IA    +D+G YT +A N +G    SA + +E  SS D+ S
Sbjct: 328  TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS 371



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 42/147 (28%), Positives = 66/147 (44%), Gaps = 13/147 (8%)

Query: 1821 IQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEW 1880
            +QQ+   + Y  R D        P F  +L   T ++EGQ    ECR+   P   ++V+W
Sbjct: 418  VQQVHSPTSYLCRPDGTTTAYFPPVFTKELQN-TAVAEGQVVVLECRVRGAPP--LQVQW 474

Query: 1881 YFNGKVLQSGHRYR--------TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
            +  G  +Q    +R        T+       L I   + ED+G +TC A N+ G A S+ 
Sbjct: 475  FRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTA 534

Query: 1933 RLNVQS--KESIIRDSQHESALEKIQY 1957
            +L V S   E+   +S  ES  +  Q+
Sbjct: 535  QLVVTSANTENCSYESMGESNNDHFQH 561



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--------L 4778
            L++  V EGQ    + ++       +QW R+G+ I ++PDF+++ +   +         L
Sbjct: 447  LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTL 506

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +I  T+ ED G FTC A    G   ++A+LVV S
Sbjct: 507  VIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 68/276 (24%), Positives = 116/276 (42%), Gaps = 25/276 (9%)

Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESE 3845
            +C  +    +E +L +    E   E++ G   D P E  +    P F  ++K + + E  
Sbjct: 739  SCEQRLISEIEYRLERSPVDESGDEVQYG---DVPVENGMA---PFFEMKLKHYKIFEGM 792

Query: 3846 GVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYI 3903
             V F CRV    +PK +I W+++GK + P    Y    D+ G  SL       +D G Y 
Sbjct: 793  PVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850

Query: 3904 CRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
              A N  G       ISC     +   NQ  RG  RS         +++  S    + D+
Sbjct: 851  IMAANPQGR------ISCTGRLMVQAVNQ--RG--RSPRSPSGHPHVRRPRSRSRDSGDE 900

Query: 3964 LYDVDKK-QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022
               + ++   P F+ Q     ++ E +  + +C+++  G P   + W  +GKP+   +  
Sbjct: 901  NEPIQERFFRPHFL-QAPGDLTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAH 957

Query: 4023 TP-IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057
               + + G  ++    V   D+G Y C ATN  G +
Sbjct: 958  KMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 993



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 45/158 (28%), Positives = 66/158 (41%), Gaps = 19/158 (12%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RV------H 3745
            PP FT E++ N  V EG  V  +CRV   G P +++ WF  G         R+       
Sbjct: 440  PPVFTKELQ-NTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRS 496

Query: 3746 TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSG 3805
            T        L I   +  DAG +TC A N +GSAT+TA+        +V+ S   +  S 
Sbjct: 497  TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ--------LVVTSANTENCSY 548

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEE 3843
            E + E         P   PI+ T    +   K   +++
Sbjct: 549  ESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQ 586



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 7/98 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-- 449
           P F K  Q+  V EG++   +CRV G P  +V WF    +I+D  + +IL  +  + A  
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500

Query: 450 -----LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
                L+I      D+G+ TC ARN  G      +L V
Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 4/96 (4%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG-L 2699
            AP F   L+S + + EG  VYLE +V     P  ++ WF  G  L     ++   + G L
Sbjct: 270  APRFIQKLRSQE-VAEGSRVYLECRVTGNPTP--RVRWFCEGKELHNTPDIQIHCEGGDL 326

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             TL I     DD+G YTC ATN  G   ++A + IE
Sbjct: 327  HTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 3/91 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV-S 3888
            P+FI +++S  V E   V  ECRV     P  R+ W+  GK L +    +   + G + +
Sbjct: 271  PRFIQKLRSQEVAEGSRVYLECRVTGNPTP--RVRWFCEGKELHNTPDIQIHCEGGDLHT 328

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            L I   + +D+G Y C A N  G D T A +
Sbjct: 329  LIIAEAFEDDTGRYTCLATNPSGSDTTSAEV 359



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 10/100 (10%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-------STHD 2827
            VF   L N    EG  +  EC V  +  P L+++WF     +     ++       ST +
Sbjct: 442  VFTKELQNTAVAEGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499

Query: 2828 FSYV-SLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
               + +L I  T+ ED+GI+TC A N  GSAT++  L  T
Sbjct: 500  PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 4/105 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG-IV 3340
            P+FI +++   ++ EG   + E R+    +P  +V WF  GK+L +    +   + G + 
Sbjct: 271  PRFIQKLRS-QEVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQ 3385
             L I   +E+++G Y C+ATN  G D+T A +      +   DS+
Sbjct: 328  TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 4/106 (3%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP F   L + E + EG   + E R+T   +P  +V W+  GK L      +  C+ G +
Sbjct: 270  APRFIQKLRSQE-VAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDL 326

Query: 3479 -ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
              L I+  + +D+G Y C A N  G   T+A + ++G  +   +S+
Sbjct: 327  HTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG--Y 4030
            PRF+ +++SQ  + E      EC++   G+P  +V WF  GK L H      I+  G   
Sbjct: 271  PRFIQKLRSQ-EVAEGSRVYLECRVT--GNPTPRVRWFCEGKEL-HNTPDIQIHCEGGDL 326

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQ 4076
              +     + +D+G Y C ATN  G D T A +   G      DS+
Sbjct: 327  HTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 11/101 (10%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR--------T 3471
            PVFT  L N   + EG+    E R+     P L+V+W+  G  ++    FR        T
Sbjct: 441  PVFTKELQNTA-VAEGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
                    L I+ T+PED+G + C A N+YG A +TA + V
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 55/243 (22%), Positives = 92/243 (37%), Gaps = 11/243 (4%)

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V    G  P F   +++ + + +G    F C V    +P  KI W+ +G+ +   +   T
Sbjct: 769  VPVENGMAPFFEMKLKHYK-IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYT 825

Query: 3201 VS-DF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT--RATINCYGKGGVYLESLQPDS 3256
            +  D  G   L    +   D G Y   A N  G      R  +    + G    S     
Sbjct: 826  IQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHP 885

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
              +     S     +  P       P F+    D+T + EG+    + ++  +  PDL  
Sbjct: 886  HVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLT-VQEGKLCRMDCKVSGLPTPDLS- 943

Query: 3317 EWFYNGKKL-PHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
             W  +GK + P         + G+  L I      ++G Y C+ATN+ G++S    L   
Sbjct: 944  -WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA 1002

Query: 3376 SKE 3378
            +KE
Sbjct: 1003 AKE 1005



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            KPP+F +K+Q   V +    R E    G P P I W +EN  + +S D   +H  +   I
Sbjct: 1008 KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             L+I+    ED+  +   A+N  G   C+A L V
Sbjct: 1068 CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/88 (27%), Positives = 41/88 (46%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+F +  +N   A G   + E ++ G P P + W ++   L         + +  G + 
Sbjct: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICS 158
            LLI+     D G YT +A+N+ G   C+
Sbjct: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCT 1096



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 34/101 (33%), Positives = 53/101 (52%), Gaps = 11/101 (10%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA-------RLKST 2694
            P+FT  L++   + EGQ V LE +V  R  P L+++WF+ G  +           + +ST
Sbjct: 441  PVFTKELQN-TAVAEGQVVVLECRV--RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 2695 FD-FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +   + TL I     +D+GI+TC A N  G A STA + +
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 32/91 (35%), Positives = 47/91 (51%), Gaps = 5/91 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS-RFKTYYD-FGF 1234
            PVF++ L N   V++G  + LECR+  +G P  ++ W     S+T  + R   + D  G+
Sbjct: 1010 PVFIEKLQNTG-VADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGY 1066

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
            + L I  AT  D G YTV A N  G    +A
Sbjct: 1067 ICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 5/117 (4%)

Query: 1698 QRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN 1757
            Q HSA       AP F   ++   VAE    + E R+   G+P  RV W   G  +  + 
Sbjct: 260  QPHSALH--FPAAPRFIQKLRSQEVAEGSRVYLECRV--TGNPTPRVRWFCEGKELHNTP 315

Query: 1758 RLTTMHDFGYV-ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ 1813
             +    + G +  L +     +D+G YTC A N  G   TS+ +F++  +S   +S+
Sbjct: 316  DIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 5/101 (4%)

Query: 764  EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
            ++  + P FI  LQ+ G + +G     E ++  V  P  ++ W K+   +T S+   S+ 
Sbjct: 1004 KEAHKPPVFIEKLQNTG-VADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMH 1060

Query: 824  --NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
              N GY+ L I     EDAG YTV A N+ G    TA + V
Sbjct: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
            PP   +K +N+ + +G   + + ++ G P P++ W K  + L +S     +   NH    
Sbjct: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            L ++   K D+G YT+ A+N  G +  +  L V
Sbjct: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 7/128 (5%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV- 3207
            PRF   +++ E + +G   + EC V    +P  ++ W+  G+ + ++  I+   + G + 
Sbjct: 271  PRFIQKLRSQE-VAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQ 3267
             L IA     D+G Y C A N  G D T A +   G      +S   +SLA      ++ 
Sbjct: 328  TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS---ESLAFKSRAGAMP 384

Query: 3268 GAQQQTPS 3275
             AQ++T S
Sbjct: 385  QAQKKTTS 392



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV-I 3616
            P F        ++E S  + ECR+    + + RV WF  GK L     ++   + G +  
Sbjct: 271  PRFIQKLRSQEVAEGSRVYLECRV--TGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            L I   ++ D G YTC ATN  G  T S ++ ++G
Sbjct: 329  LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 51/224 (22%), Positives = 95/224 (42%), Gaps = 10/224 (4%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH-DF-GYVALDIIDLIAED 1513
            + EG  V F C++    +   K+ WFK+G+ ++       I  D  G  +L       +D
Sbjct: 788  IFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 845

Query: 1514 SGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEV 1573
             G YT  A N  G    + RL  ++     RS ++ +G   ++    RS+    D  + +
Sbjct: 846  DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR-DSGDENEPI 904

Query: 1574 TTQ--APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE-TN 1630
              +   P    +  ++ ++EG+    + ++  +   T  + W  + KP++  S       
Sbjct: 905  QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP--TPDLSWQLDGKPVRPDSAHKMLVR 962

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674
              G  +L I      D+G YTC A N  G+   S   +V +K++
Sbjct: 963  ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 1006



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+ V EG+  +   +++    P + W  +G  + P++    ++ E     L+I      D
Sbjct: 919  DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             G +TC AT  AGQ   S +LVV +K
Sbjct: 979  AGIYTCIATNRAGQNSFSLELVVAAK 1004



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 10/99 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR--------T 3880
            PP F  ++++  V E + V  ECRV  +  P L+++W+R G  +     +R        T
Sbjct: 440  PPVFTKELQNTAVAEGQVVVLECRV--RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
                   +L I   + ED+G + C A ND+G   + A +
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL 536



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 2908 YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFG 2967
            +P     I      ++ EG  ++LE +V    +P  ++ W+  GK L      ++  + G
Sbjct: 267  FPAAPRFIQKLRSQEVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGG 324

Query: 2968 FV-TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
             + TL + + +E D+G YTC A N  G   TS+ V+
Sbjct: 325  DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF 360



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 3/104 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-S 695
           P+FI  L+S    EG +++ E R+   G+PT ++ W   G+ +  +         G + +
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRV--TGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQ 739
           L +      D+G YTC A + +G   T A + +   ++ +  S+
Sbjct: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 11/91 (12%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RI------TK 2427
            PVFT+ LQN   + EGQ    +CR+   G P L+V+WFR    I+DS   RI      + 
Sbjct: 441  PVFTKELQNTA-VAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 2428 THDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                   ++ I+    ED G++ C A N  G
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYG 528



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA-TGS 3742
            E+ +  ++ + P   +E   N  V +G PV  +CRV  +G P  +I W         +  
Sbjct: 998  ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTD 1055

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            RV    D  G+I L I      DAG YT  A N+ G  + TA++
Sbjct: 1056 RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 11/104 (10%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI------- 2293
            PP F  EL+ T  V EG+    EC+V     P L+++++  G  +Q +  F I       
Sbjct: 440  PPVFTKELQNTA-VAEGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRS 496

Query: 2294 TFDFGYV-SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
            T +   + +L I    PEDAG ++  A N  G  TS   + VT+
Sbjct: 497  TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR-NEKLIEDSSRITKTHD-FGY 2433
            PVF + LQN   + +G     +CR++ V  P  ++ W + NE L   + R++   D  GY
Sbjct: 1010 PVFIEKLQNT-GVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 1066

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
            + + I     ED G Y   A N  G
Sbjct: 1067 ICLLIQGATKEDAGWYTVSAKNEAG 1091



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 4/97 (4%)

Query: 634  YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--F 691
            + PP FI  L++    +G  +  E R+  +G P  +I W K  +S+  S+   S+ +   
Sbjct: 1007 HKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNH 1064

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            GYI L +     +D+G YT  A +  G+    A L V
Sbjct: 1065 GYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 4/103 (3%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV- 828
           P+FI+ L+   E+ EG   + E ++T   +PT RV W+ +G+ +  +  I      G + 
Sbjct: 271 PRFIQKLRSQ-EVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327

Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTAD 871
           +L I     +D G YT  A N  G   ++A + +   S+  +D
Sbjct: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSD 370



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 53/206 (25%), Positives = 83/206 (40%), Gaps = 18/206 (8%)

Query: 994  TTSANLTIVT---KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLK 1050
            TTS +LTI +   K  +      P  +  +Q +   + Y  R +        P F   L+
Sbjct: 390  TTSVSLTIGSSSPKTGVTTAVIQPLSVP-VQQVHSPTSYLCRPDGTTTAYFPPVFTKELQ 448

Query: 1051 GTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN--RI------QTYHDFGYVA 1102
             T  + EGQ    E RV     L   V+W+  G +I  +   RI       T        
Sbjct: 449  NT-AVAEGQVVVLECRVRGAPPLQ--VQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICT 505

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L IA    ED+G++T  ARN  G A  +A + V T ++ +  S          H +    
Sbjct: 506  LVIAETFPEDAGIFTCSARNDYGSATSTAQLVV-TSANTENCSYESMGESNNDHFQHFPP 564

Query: 1163 VEPMYQIE--EISKSKPVFVQPLSNP 1186
              P+ +    E++  KP  +Q ++NP
Sbjct: 565  PPPILETSSLELASKKPSEIQQVNNP 590



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 36/140 (25%), Positives = 62/140 (44%), Gaps = 5/140 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV- 2167
            P F+  L S E + EG R + ECRV    +P   + WF  G+++      +   + G + 
Sbjct: 271  PRFIQKLRSQE-VAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL-EAQ 2226
             L I   + +D+G Y C ATN  G    +  + + G  +   D++      +   + +AQ
Sbjct: 328  TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387

Query: 2227 GHSTRIEVEEPKISPPRFVT 2246
              +T + +     SP   VT
Sbjct: 388  KKTTSVSLTIGSSSPKTGVT 407



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 4/94 (4%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV- 967
            P F   ++ Q  + EG   + E R+   G+ T RV W  +G+ +  +  I      G + 
Sbjct: 271  PRFIQKLRSQ-EVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L I      D G YTC A N  G  TTSA + I
Sbjct: 328  TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 11/114 (9%)

Query: 2900 RPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSR 2959
            RP    T Y  P +   +     + EGQV+ LE +V  +  P L+++W+  G  ++    
Sbjct: 430  RPDGTTTAYFPPVFTKELQ-NTAVAEGQVVVLECRV--RGAPPLQVQWFRQGSEIQDSPD 486

Query: 2960 FKL--------TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS 3005
            F++               TL + + +  D+GI+TC A N  G A +++ +  TS
Sbjct: 487  FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 10/100 (10%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK--------TT 2029
            P F K ++N  V EG  V LE  +     P ++V+W+  G  +Q    F+        T 
Sbjct: 441  PVFTKELQNTAVAEGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498

Query: 2030 YDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                   L I   + ED G + C A N  G A +T+ + V
Sbjct: 499  EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 11/101 (10%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR--------T 2160
            PVF   L +   + EG     ECRV     P L + WF  G +I+    +R        T
Sbjct: 441  PVFTKELQNTA-VAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                    L I  T+ ED+G + C A N  G A +T  L V
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE- 4785
            L+   ++EG P  F  ++    KP I W ++G  I    D   I    +    +  T   
Sbjct: 783  LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842

Query: 4786 -EDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +D G +T  A    G++  + +L+V++
Sbjct: 843  LDDDGNYTIMAANPQGRISCTGRLMVQA 870



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 58  RQPITAGRP-GEPSPPIFEQIFK--------NARFAQGGNAKFEGKLRGNPTPVVSWTRK 108
           R+P +  R  G+ + PI E+ F+        +    +G   + + K+ G PTP +SW   
Sbjct: 888 RRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 947

Query: 109 KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
             P+   + + M   E  G  SL+I+ +   D G YTC A N+ G+
Sbjct: 948 GKPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQ 992



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 39/154 (25%), Positives = 69/154 (44%), Gaps = 9/154 (5%)

Query: 2311 DAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELES-AEPFKRPEIPE 2369
            D+G  S K   +     SA    +  +G +  E + P      ++ +  A P  R   P+
Sbjct: 201  DSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQ 260

Query: 2370 PVTRQR----PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI 2425
            P +       P F Q L++   + EG   + +CR+   G+PT +V WF   K + ++  I
Sbjct: 261  PHSALHFPAAPRFIQKLRS-QEVAEGSRVYLECRV--TGNPTPRVRWFCEGKELHNTPDI 317

Query: 2426 TKTHDFGYV-SMTISHVRDEDEGVYMCRASNLLG 2458
                + G + ++ I+   ++D G Y C A+N  G
Sbjct: 318  QIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSG 351



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 8/108 (7%)

Query: 2488 QKLEQPHERRSE-EPDREFEKPI---FTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFE 2543
            Q L  PH R+S  +P      P    F Q L    E+ EG   + E RV   G+P+ R  
Sbjct: 247  QDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRS-QEVAEGSRVYLECRVT--GNPTPRVR 303

Query: 2544 WYINGVELKMGSRFRTTHDFGFV-TLDINSVVANDAGLYMCKAINRAG 2590
            W+  G EL      +   + G + TL I     +D G Y C A N +G
Sbjct: 304  WFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSG 351



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 4/108 (3%)

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD---FQIH 4460
            PV+    P F  K++  ++FE     F     G P P I W+++   I    D    Q  
Sbjct: 770  PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 829

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
               T S+       ++D   +  +A N  G   C+  L+V+   ++GR
Sbjct: 830  LDGTCSLHTTAST-LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR 876



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGYV 1768
            PVF   +++  VA+      E R++ V  P+  + W +    +  S    +MH  + GY+
Sbjct: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQ--IFWKKENESLTHSTDRVSMHQDNHGYI 1067

Query: 1769 ALNMKYVNPEDSGTYTCRAINELG 1792
             L ++    ED+G YT  A NE G
Sbjct: 1068 CLLIQGATKEDAGWYTVSAKNEAG 1091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGY 2299
            PP F+ +L+ T  V +G     EC+V  V  P +  +   N     S  R  +  D  GY
Sbjct: 1009 PPVFIEKLQNTG-VADGYPVRLECRVLGVPPPQIFWK-KENESLTHSTDRVSMHQDNHGY 1066

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALG--HCTSAISMTVT 2335
            + L IQ    EDAG Y+V A N  G   CT+ + + ++
Sbjct: 1067 ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 6/93 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG--Y 1501
            PRF+ + +S E V EG  V+ EC++    +   +V WF  G+ +      + IH  G   
Sbjct: 271  PRFIQKLRSQE-VAEGSRVYLECRV--TGNPTPRVRWFCEGKELHNTPDIQ-IHCEGGDL 326

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
              L I +   +D+G YTC A N  G+D  S  +
Sbjct: 327  HTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV 359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 3/105 (2%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV- 1635
            AP     L++ E+ EG R + E R+    + T +V W+   K L +          G + 
Sbjct: 270  APRFIQKLRSQEVAEGSRVYLECRV--TGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQ 1680
             L I     +D+G YTC A N  G   TS    +    S   +S+
Sbjct: 328  TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 11/97 (11%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK--------T 1228
            PVF + L N   V+EG+ + LECR+   G P ++V+WF  G  +     F+        T
Sbjct: 441  PVFTKELQNTA-VAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
                    L I      D G +T  A N  GSA ++A
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTA 534



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 10/101 (9%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL--------LTGSRVKT 3608
            PP FT    +  ++E      ECR+       ++V+WF  G  +        L      T
Sbjct: 440  PPVFTKELQNTAVAEGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 3609 INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                    L I   +  DAG++TC A N +G AT + +L V
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 5/95 (5%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHD-FGY 1100
            P F+  L+ T  + +G     E RV         + W    + +T S +R+  + D  GY
Sbjct: 1010 PVFIEKLQNTG-VADGYPVRLECRVLGVPP--PQIFWKKENESLTHSTDRVSMHQDNHGY 1066

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            + L I     ED+G YTV A+N AG    +A + V
Sbjct: 1067 ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/107 (24%), Positives = 40/107 (37%)

Query: 52  VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
           V+ SGD              P FE   K+ +  +G    F  ++ GNP P + W +    
Sbjct: 757 VDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 816

Query: 112 LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
           +   + +     +  G  SL        D+G YT  A N  G   C+
Sbjct: 817 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCT 863



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVS 2832
            VFI  L N    +G  +  EC V     P  +I W   N+ L   T   S H  +  Y+ 
Sbjct: 1011 VFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYIC 1068

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I    +ED+G YT  A N  G  + +  L
Sbjct: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 2/71 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG--MYHFD 4168
            P F+    +  V EG      CRVTG+P PRV W   G  + N    ++  +G  ++   
Sbjct: 271  PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330

Query: 4169 IPKTRQYDTGK 4179
            I +  + DTG+
Sbjct: 331  IAEAFEDDTGR 341



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 11/103 (10%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPL--------LHKNRFT 4023
            PP F  ++Q+ T++ E +    EC++   G P ++V+WF  G  +        L K   +
Sbjct: 440  PPVFTKELQN-TAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRS 496

Query: 4024 PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
                     +     +PED+G + C A N YG   + A +  T
Sbjct: 497  TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 4/110 (3%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S +++ +    E+  PP F     +  +++      ECR++ V     ++ W    + L 
Sbjct: 994  SFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLT 1051

Query: 3602 TGS-RVKTIND-FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              + RV    D  G++ L I G  + DAG YT  A N  G  + + +L V
Sbjct: 1052 HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/57 (31%), Positives = 27/57 (47%)

Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            E VV   +A  PPVF+       V +G   R  CRV G P P++ W     ++ + +
Sbjct: 998  ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 1054



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 10/102 (9%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--------TET 1629
            P+ T  L+N  + EGQ    E R+       L+V+W+     ++    F        +  
Sbjct: 441  PVFTKELQNTAVAEGQVVVLECRVRGAPP--LQVQWFRQGSEIQDSPDFRILQKKPRSTA 498

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
                   L I    PED+G +TC A N  G A ++   +V S
Sbjct: 499  EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 11/99 (11%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK--------T 3200
            P FT  +QN   + +GQ    EC V     P ++++W+  G  ++ S   +        T
Sbjct: 441  PVFTKELQNT-AVAEGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
                    L IA T   D+G + C A N YG   + A +
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL 536



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYD-FGYV 2035
            P F + ++N  V +G+PV LE  +  V  P  ++ W      +     R     D  GY+
Sbjct: 1010 PVFIEKLQNTGVADGYPVRLECRVLGV--PPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             L I  A  ED G Y   A N  G    T+ + V
Sbjct: 1068 CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 12/98 (12%)

Query: 1451 KSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG-------- 1500
            K ++N  V EGQ V  EC++       L+V+WF+ G  +     FR +            
Sbjct: 445  KELQNTAVAEGQVVVLECRVRGAPP--LQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEE 502

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS 1538
               L I +   ED+GI+TC A N  G+   + +L   S
Sbjct: 503  ICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF- 962
            E+ + P F   +++   + +G     E R+  +G    ++ W K+   +  S+   +   
Sbjct: 1005 EAHKPPVFIEKLQNT-GVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQ 1061

Query: 963  -NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             N GY+ L I+  T  DAG YT  A N  G  + +A L +
Sbjct: 1062 DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 5/98 (5%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTSND- 1898
            ++ P FI +L   T +++G     ECR+   P P  ++ W   N  +  S  R     D 
Sbjct: 1007 HKPPVFIEKLQN-TGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDN 1063

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             G+  L I     ED+G YT  A N  G    + RL+V
Sbjct: 1064 HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 13/110 (11%)

Query: 3039 QPDDDTGR--PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
            +PD  T    PP FT   ++   ++EGQ+   E  +   G   + ++WF  G  I+ S  
Sbjct: 430  RPDGTTTAYFPPVFTKELQNTA-VAEGQVVVLECRV--RGAPPLQVQWFRQGSEIQDSPD 486

Query: 3097 IR--------TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
             R        T     +  L I  T   D+G ++C A N +G A  + +L
Sbjct: 487  FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL 536



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTVYD-MGF 3886
            PP FI ++++  V +   VR ECRV     P  +I W + N  L  S  R     D  G+
Sbjct: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 1066

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
            + L I     ED+G Y   A N+ G
Sbjct: 1067 ICLLIQGATKEDAGWYTVSAKNEAG 1091



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 11/91 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR--------T 2559
            P+FT+ L   + + EGQ    E RV   G P L+ +W+  G E++    FR        T
Sbjct: 441  PVFTKELQNTA-VAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 2560 THDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   TL I      DAG++ C A N  G
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYG 528



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 8/95 (8%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD---Y 1367
            P F   L N    +G  V LECR+  +G    ++ W    + + T    R +   D   Y
Sbjct: 1010 PVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESL-THSTDRVSMHQDNHGY 1066

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            + L +     ED+G YT  A N+ G  + SC  R+
Sbjct: 1067 ICLLIQGATKEDAGWYTVSAKNEAG--IVSCTARL 1099


>AB023209-1|BAA76836.1|  772|Homo sapiens KIAA0992 protein protein.
          Length = 772

 Score =  206 bits (504), Expect = 1e-51
 Identities = 118/375 (31%), Positives = 198/375 (52%), Gaps = 13/375 (3%)

Query: 214 DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
           + ++  ++KV + E RL+ E+ +R  + +  V ES  ++    D  +     P    K +
Sbjct: 341 EETANQEYKVSSCEQRLISEIEYR--LERSPVDESGDEVQYG-DVPVENGMAPFFEMKLK 397

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS-- 331
           + K+ EG    F  +++GNP+P++ WFK+G+++   + H  I      T  +  T  +  
Sbjct: 398 HYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLD 457

Query: 332 DSGHYTLLAENPNGCIVTSGYLAVESPTE---SYVQDQRSQYITDTQQRETE---ERIEI 385
           D G+YT++A NP G I  +G L V++  +   S        ++   + R  +   E   I
Sbjct: 458 DDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPI 517

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            E+   P F++   D  V EGK+ R DC+V+G P P+++W ++ + +R D  HK+LV E+
Sbjct: 518 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 577

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
           G H+L+I  VT  D+G+ TC+A N++G+ +F   L V  KE    P F+E+     V +G
Sbjct: 578 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 637

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDG-GASTLDIPRAKASDAAWYQC 563
            PV L  R +G P P+I W+K+   +  + + + +H D  G   L I  A   DA WY  
Sbjct: 638 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 697

Query: 564 TAQNVAGSTATRARL 578
           +A+N AG  +  ARL
Sbjct: 698 SAKNEAGIVSCTARL 712



 Score =  104 bits (250), Expect = 7e-21
 Identities = 79/325 (24%), Positives = 137/325 (42%), Gaps = 28/325 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTL 4571
            P F +  ++  +  G  V    +V G     +YW K+GK++ P   +  ++ D  GT +L
Sbjct: 390  PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 449

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-----------KPQTKAA- 4619
                +   D G Y  +A N  G   C    +V     + +            +P++++  
Sbjct: 450  HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 509

Query: 4620 ----NAP-------PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP-SK 4667
                N P       P  ++   D  V EG+     CK+ G P P + W    K ++P S 
Sbjct: 510  SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 569

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +  + R    ++L I      D G Y C+A N AG+ + + +L V   +       +  L
Sbjct: 570  HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 629

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYE 4785
            ++  V +G P + + ++     P I W +E   +  + D   +H+ N+    LLI    +
Sbjct: 630  QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 689

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
            ED G +T  A   AG V  +A+L V
Sbjct: 690  EDAGWYTVSAKNEAGIVSCTARLDV 714



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 90/354 (25%), Positives = 150/354 (42%), Gaps = 24/354 (6%)

Query: 2940 DPDLKIEWYFNGKVLEQGS-RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +P  KI W+ +GK +   S  + +  D  G  +L        D G YT  A N +G    
Sbjct: 416  NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISC 475

Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQ-QPDDDTGRPPEFTTVFKD 3056
            +  +   + +   +R + P+   G   ++      R    + +P  +    P F     D
Sbjct: 476  TGRLMVQAVN---QRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGD 532

Query: 3057 IVDISEGQIAHYEASL--IPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILG 3112
            +  + EG++   +  +  +PT D S    W  +GK +  +++H++  V   G+  L I  
Sbjct: 533  LT-VQEGKLCRMDCKVSGLPTPDLS----WQLDGKPVRPDSAHKM-LVRENGVHSLIIEP 586

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172
              + D+G Y+C ATN+ GQ   S++L    K   + P F   +QN  G+ DG     EC 
Sbjct: 587  VTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN-TGVADGYPVRLECR 645

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHST-RIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
            V+ V  P  +I W    + + HST R+    D  G++ L I      D+G Y   A N+ 
Sbjct: 646  VLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 703

Query: 3231 GEDFTRATINCYGKGGVYLESLQPDSL---AKIRELESLQGAQQQTPSTPSAEP 3281
            G     A ++ Y +     +S +P  +   A      S QG   +    P A P
Sbjct: 704  GIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANP 757



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 63/236 (26%), Positives = 101/236 (42%), Gaps = 9/236 (3%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA-SNRLTTMHDF-GY 1767
            AP F M +K  ++ E     F  R+   G+PK ++ W ++G  I   S+  T   D  G 
Sbjct: 389  APFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 446

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+      +D G YT  A N  G    +  L VQ+        +  S    +++    
Sbjct: 447  CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 506

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887
            SR    E+  +          Q  G   + EG+    +C++   P P++   W  +GK +
Sbjct: 507  SRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKPV 564

Query: 1888 Q--SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            +  S H+     + G  +L I  V   D+G YTC A N  GQ   S+ L V +KE+
Sbjct: 565  RPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 619



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 72/247 (29%), Positives = 105/247 (42%), Gaps = 15/247 (6%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            V  E G AP F + L + + + EG    F  R+    +P  K+ W+ +GK +   S   T
Sbjct: 382  VPVENGMAPFFEMKLKHYK-IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYT 438

Query: 3472 FC-DF-GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGME 3529
               D  G   L  + +  +D G Y   A N  G    T  + VQ         + P G  
Sbjct: 439  IQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG-H 497

Query: 3530 GTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDS 3587
              + +  +    SG  D   P  E    P F   P DL + E      +C++  +P  D 
Sbjct: 498  PHVRRPRSRSRDSG--DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL 555

Query: 3588 SMRVEWFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            S    W  +GKP+   S  K  + + G   L I  V  RDAG+YTC ATNR G+ + S +
Sbjct: 556  S----WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLE 611

Query: 3647 LQVKGRQ 3653
            L V  ++
Sbjct: 612  LVVAAKE 618



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 11/234 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--FGYI 694
           P F + LK     EG  + F  R+   G+P  KI W K+G+ I   S   +I R   G  
Sbjct: 390 PFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 447

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
           SL   +  + D G YT  A +  G       L V       R+ + P    ++++    S
Sbjct: 448 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 507

Query: 755 K--YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
           +      E I+E+   RP F++   DL  +QEG+    + +++ +  PT  + W  DG+P
Sbjct: 508 RDSGDENEPIQERFF-RPHFLQAPGDL-TVQEGKLCRMDCKVSGL--PTPDLSWQLDGKP 563

Query: 813 ITA-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           +   S+    +   G  SL I  + + DAG YT  A N+ G+   +  + VAA+
Sbjct: 564 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 617



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 55/192 (28%), Positives = 80/192 (41%), Gaps = 8/192 (4%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILI 4469
            P F +      V E +  R + +  G P P + W  +  P++ +S    +   +    LI
Sbjct: 524  PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 583

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I  V   D+ ++  +A NR G    S  LVV  K         PP F    QN  V  G 
Sbjct: 584  IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-----PPVFIEKLQNTGVADGY 638

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYECV 4587
             VRL+ +V G  P  ++W K  + +        + +D  G   LLI  A  +D+G Y   
Sbjct: 639  PVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVS 698

Query: 4588 AINSAGEARCDA 4599
            A N AG   C A
Sbjct: 699  AKNEAGIVSCTA 710



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 68/225 (30%), Positives = 100/225 (44%), Gaps = 14/225 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN-DF-GF 3752
            P F +++K +  + EG PV F CRV   G+P  +I WF +G+  +  S  +T+  D  G 
Sbjct: 390  PFFEMKLK-HYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 446

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
             +L        D G YT  A N  G  + T ++   A   +    + P+  SG       
Sbjct: 447  CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQA---VNQRGRSPRSPSGHPHVRRP 503

Query: 3813 RGRISDAPKE-EPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
            R R  D+  E EPI      P F+      TV+E +  R +C+V     P L   W  +G
Sbjct: 504  RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDG 561

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            K + P       V + G  SL I  V + D+G Y C A N  G++
Sbjct: 562  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 606



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 90/358 (25%), Positives = 144/358 (40%), Gaps = 50/358 (13%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KTGHRFRPAYEFDY 1367
            AP F   L + +  EG  V   CR+   G+   ++ WF +GK I  K+ H +    + D 
Sbjct: 389  APFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDH-YTIQRDLDG 445

Query: 1368 V-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426
              +L   +   +D G YT  A N  G    +  L V A        + PSG   ++    
Sbjct: 446  TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 505

Query: 1427 TSRYK--KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484
             SR    + + I E    +P F+  P  +  V EG+    +CK+  +   +L   W  +G
Sbjct: 506  RSRDSGDENEPIQERF-FRPHFLQAPGDL-TVQEGKLCRMDCKVSGLPTPDLS--WQLDG 561

Query: 1485 QPVTIGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            +PV      +  + + G  +L I  + + D+GIYTC A N                    
Sbjct: 562  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATN-------------------- 601

Query: 1544 RSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIP 1603
            R+ QN   LE +   ++  K              P+    L+N  + +G     E R++ 
Sbjct: 602  RAGQNSFSLELVVAAKEAHK-------------PPVFIEKLQNTGVADGYPVRLECRVLG 648

Query: 1604 VSDATLKVEWYHNNKPLK-SGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            V     ++ W   N+ L  S  R +   +N G++ L I     ED+G YT  A N  G
Sbjct: 649  VPPP--QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 704



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 65/241 (26%), Positives = 102/241 (42%), Gaps = 11/241 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN-D 3611
            E+G  P F        + E     F CR+    +   ++ WF +GK +   S   TI  D
Sbjct: 385  ENGMAPFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRD 442

Query: 3612 F-GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTE 3670
              G   L        D G YT  A N  G  + + +L V+        P+ PS       
Sbjct: 443  LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 502

Query: 3671 SIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRID 3730
               +  ++  + E I    E+   P F ++   ++ V EG     DC+V   G PT  + 
Sbjct: 503  PRSRSRDSGDENEPI---QERFFRPHF-LQAPGDLTVQEGKLCRMDCKVS--GLPTPDLS 556

Query: 3731 WFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
            W  +G+P    S    L  + G  +L I+ + +RDAG YTC ATN+ G  + + ++  +A
Sbjct: 557  WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAA 616

Query: 3790 K 3790
            K
Sbjct: 617  K 617



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 14/239 (5%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
            +P  ++ W+KDG+ I+  S   +I     G  SL+      +D G+YT+ A N  G    
Sbjct: 416  NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISC 475

Query: 857  TASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIK 916
            T  + V A +        P    ++ +                  + E   +P F     
Sbjct: 476  TGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEP----IQERFFRPHFLQAPG 531

Query: 917  DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GYVALTIKSVT 975
            D ++++EG     + ++   G  T  + W  DG+PV   S         G  +L I+ VT
Sbjct: 532  D-LTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 588

Query: 976  VHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTE 1034
              DAG YTC A N  GQ + S  L +  K+      + P  +EK+Q    A  Y  R E
Sbjct: 589  SRDAGIYTCIATNRAGQNSFSLELVVAAKE----AHKPPVFIEKLQNTGVADGYPVRLE 643



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 57/211 (27%), Positives = 91/211 (43%), Gaps = 11/211 (5%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA-RFHITFDF-GYVSLDIQHCVPED 2311
            +FEG    F C+V    +P  +I ++ +GK +   +  + I  D  G  SL       +D
Sbjct: 401  IFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 458

Query: 2312 AGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPV 2371
             G Y++ A N  G  +    + V A        + P G   +R   S       E  EP+
Sbjct: 459  DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDE-NEPI 517

Query: 2372 TRQ--RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-DSSRITKT 2428
              +  RP F Q   ++  +QEG+    DC++   G PT  + W  + K +  DS+     
Sbjct: 518  QERFFRPHFLQAPGDL-TVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLV 574

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             + G  S+ I  V   D G+Y C A+N  G+
Sbjct: 575  RENGVHSLIIEPVTSRDAGIYTCIATNRAGQ 605



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 59/238 (24%), Positives = 104/238 (43%), Gaps = 12/238 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DF-GFVALDIIHATSAD 1246
            + EG  +   CR+   G+P  ++ WF +G+ ++  S   T   D  G  +L    +T  D
Sbjct: 401  IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 458

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT 1306
             G YT+ A N  G    +  + V   +      ++      ++     +R +    E I 
Sbjct: 459  DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 518

Query: 1307 V-MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
                 P F +A  ++   EG    ++C++   G  T  + W  +GKP++     +     
Sbjct: 519  ERFFRPHFLQAPGDLTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLVRE 576

Query: 1366 DYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            + V +L +  V   D+G+YTC ATN+ G+   S  L V AK+      + P  +EK+Q
Sbjct: 577  NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE----AHKPPVFIEKLQ 630



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 58/224 (25%), Positives = 96/224 (42%), Gaps = 11/224 (4%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYV-SLDITHTYEEDSG 2844
            EG  + F C V  + +P  KI WF + K + P    Y    D     SL  T +  +D G
Sbjct: 403  EGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 460

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904
             YT  A N +G  + +G L     + +    + P+  +G   V +        G      
Sbjct: 461  NYTIMAANPQGRISCTGRLMV---QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPI 517

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK-LT 2963
               + +P + +    +  + EG++  ++ +V     PDL   W  +GK +   S  K L 
Sbjct: 518  QERFFRPHF-LQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKPVRPDSAHKMLV 574

Query: 2964 SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
             + G  +L +  V  RD+GIYTC A N+ G+   S  +   +K+
Sbjct: 575  RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 618



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 62/244 (25%), Positives = 105/244 (43%), Gaps = 16/244 (6%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN 963
            E+   P F+  +K    I EG    F  R+   G+   ++ W KDG+ +   S   T   
Sbjct: 385  ENGMAPFFEMKLK-HYKIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQR 441

Query: 964  F--GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
               G  +L   + T+ D G+YT  A N  G+ + +  L +          + P G   ++
Sbjct: 442  DLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVR 501

Query: 1022 YLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVE 1078
                 SR S    E ++    +P FL    G   + EG+    + +V   P  DL+    
Sbjct: 502  RPRSRSRDSGDENEPIQERFFRPHFL-QAPGDLTVQEGKLCRMDCKVSGLPTPDLS---- 556

Query: 1079 WYFNGKQIT--SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            W  +GK +   SA+++    + G  +L I  V + D+G+YT +A N AG+   S  + V 
Sbjct: 557  WQLDGKPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA 615

Query: 1137 TRSS 1140
             + +
Sbjct: 616  AKEA 619



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 64/247 (25%), Positives = 102/247 (41%), Gaps = 13/247 (5%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            LE+    ES +  +  ++P       P F   L++   I EG    F CR+   G+P  K
Sbjct: 365  LERSPVDESGDEVQYGDVPVE-NGMAPFFEMKLKHY-KIFEGMPVTFTCRV--AGNPKPK 420

Query: 2410 VEWFRNEKLIEDSS-RITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX 2467
            + WF++ K I   S   T   D  G  S+  +    +D+G Y   A+N  G         
Sbjct: 421  IYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLM 480

Query: 2468 XXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE--PDRE-FEKPIFTQVLTGPSELWEGQ 2524
                       + P G   +++         +E  P +E F +P F Q   G   + EG+
Sbjct: 481  VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA-PGDLTVQEGK 539

Query: 2525 HAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THDFGFVTLDINSVVANDAGLYMC 2583
                + +V  +  P L   W ++G  ++  S  +    + G  +L I  V + DAG+Y C
Sbjct: 540  LCRMDCKVSGLPTPDL--SWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTC 597

Query: 2584 KAINRAG 2590
             A NRAG
Sbjct: 598  IATNRAG 604



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 70/295 (23%), Positives = 123/295 (41%), Gaps = 22/295 (7%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDF-GYV 2035
            P F   +K+ ++ EG PV    T     +P  ++ W+ +G+ +  +   +    D  G  
Sbjct: 390  PFFEMKLKHYKIFEGMPVTF--TCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 447

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA-----KSGLYLDTLDEQRLKKIQE 2090
            +L    +  +D G Y   A N  G    T  + V A     +S          R  + + 
Sbjct: 448  SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 507

Query: 2091 LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQ 2150
             +  +  +PI+E     RP FL A   L  ++EG     +C+V  +  P L+  W  +G+
Sbjct: 508  RDSGDENEPIQERF--FRPHFLQAPGDL-TVQEGKLCRMDCKVSGLPTPDLS--WQLDGK 562

Query: 2151 KIRAGHRYRT-THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
             +R    ++    + G  +L I    + D+G Y C ATN+ G+   +  L VA       
Sbjct: 563  PVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---- 618

Query: 2210 DTQHPNGLEKIRQL-EAQGHSTRIEVEEPKISPPR--FVTELRGTTHVFEGKTAH 2261
              + P  +EK++    A G+  R+E     + PP+  +  E    TH  +  + H
Sbjct: 619  AHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 673



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 72/271 (26%), Positives = 111/271 (40%), Gaps = 22/271 (8%)

Query: 2082 EQRLKKIQELEKYERPKPIEEE----QPGQRPV------FLTALTSLENLKEGDRAHFEC 2131
            EQRL  I E+E      P++E     Q G  PV      F         + EG    F C
Sbjct: 354  EQRL--ISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTC 411

Query: 2132 RVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNK 2189
            RV    +P   I WF +G++I      Y    D  G  +L    +  +D G Y   A N 
Sbjct: 412  RVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANP 469

Query: 2190 LGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE--EPKISPPRFVTE 2247
             G    T  L V          + P+G   +R+  ++   +  E E  + +   P F+ +
Sbjct: 470  QGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFL-Q 528

Query: 2248 LRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ-SAARFHITFDFGYVSLDIQH 2306
              G   V EGK    +C+V  +  P+L  +   +GK ++  +A   +  + G  SL I+ 
Sbjct: 529  APGDLTVQEGKLCRMDCKVSGLPTPDLSWQL--DGKPVRPDSAHKMLVRENGVHSLIIEP 586

Query: 2307 CVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
                DAG Y+  A N  G  + ++ + V AK
Sbjct: 587  VTSRDAGIYTCIATNRAGQNSFSLELVVAAK 617



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 51/219 (23%), Positives = 92/219 (42%), Gaps = 30/219 (13%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLR 324
           P   Q P +  +QEG   +   ++SG P P ++W  +G+ +   + H+++   N   +L 
Sbjct: 524 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 583

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +      D+G YT        CI T+      +   S+                 E  + 
Sbjct: 584 IEPVTSRDAGIYT--------CIATN-----RAGQNSF---------------SLELVVA 615

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
             E    P F++  Q+  V +G   R +CRV G P P++ W   +  +    +   +  +
Sbjct: 616 AKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 675

Query: 445 S-GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           + G   L+I   T  D+G  T  A+N++G  +   RL+V
Sbjct: 676 NHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 714



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 15/228 (6%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA---RLKSTFDF 2697
            AP F   LK Y K+ EG  V    +V     P  KI WFK+G  ++  +    ++   D 
Sbjct: 389  APFFEMKLKHY-KIFEGMPVTFTCRVAGNPKP--KIYWFKDGKQISPKSDHYTIQRDLD- 444

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL----LGESLHPDSLDRI 2753
            G  +L   +   DD G YT  A N  G    T  + ++  +         S HP  + R 
Sbjct: 445  GTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH-VRRP 503

Query: 2754 GALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN 2813
             +                    F+    ++  +EG     +C V  S  PT  + W  + 
Sbjct: 504  RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV--SGLPTPDLSWQLDG 561

Query: 2814 KPLPSGTRYKS-THDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
            KP+   + +K    +    SL I      D+GIYTC ATN  G  + S
Sbjct: 562  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS 609



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 52/219 (23%), Positives = 93/219 (42%), Gaps = 16/219 (7%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKN-RFTPI 4025
            V+    P F  +++       M  T F C++A  G+P  K+ WF +GK +  K+  +T  
Sbjct: 384  VENGMAPFFEMKLKHYKIFEGMPVT-FTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQ 440

Query: 4026 YDF-GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK---PGIVYDSQLPKHM 4081
             D  G  +++      +D G Y   A N  G       I  TG+     +    + P+  
Sbjct: 441  RDLDGTCSLHTTASTLDDDGNYTIMAANPQGR------ISCTGRLMVQAVNQRGRSPRSP 494

Query: 4082 KSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPR 4141
                 +R   +  + + ++     +    P F+  P  +TV+EG+  R  C+V+G P P 
Sbjct: 495  SGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPD 554

Query: 4142 VMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYDTG 4178
            + W L+G  +   S +K+    +G++   I      D G
Sbjct: 555  LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 593



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 68/276 (24%), Positives = 116/276 (42%), Gaps = 25/276 (9%)

Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESE 3845
            +C  +    +E +L +    E   E++ G   D P E  +    P F  ++K + + E  
Sbjct: 352  SCEQRLISEIEYRLERSPVDESGDEVQYG---DVPVENGMA---PFFEMKLKHYKIFEGM 405

Query: 3846 GVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYI 3903
             V F CRV    +PK +I W+++GK + P    Y    D+ G  SL       +D G Y 
Sbjct: 406  PVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 463

Query: 3904 CRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
              A N  G       ISC     +   NQ  RG  RS         +++  S    + D+
Sbjct: 464  IMAANPQGR------ISCTGRLMVQAVNQ--RG--RSPRSPSGHPHVRRPRSRSRDSGDE 513

Query: 3964 LYDVDKK-QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022
               + ++   P F+ Q     ++ E +  + +C+++  G P   + W  +GKP+   +  
Sbjct: 514  NEPIQERFFRPHFL-QAPGDLTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAH 570

Query: 4023 TP-IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057
               + + G  ++    V   D+G Y C ATN  G +
Sbjct: 571  KMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 606



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 2/123 (1%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            KPP+F +K+Q   V +    R E    G P P I W +EN  + +S D   +H  +   I
Sbjct: 621  KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 680

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L+I+    ED+  +   A+N  G   C+A L V  +  Q      P     +A      
Sbjct: 681  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAAL 740

Query: 4527 SGQ 4529
            S Q
Sbjct: 741  SDQ 743



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 55/243 (22%), Positives = 92/243 (37%), Gaps = 11/243 (4%)

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V    G  P F   +++ + + +G    F C V    +P  KI W+ +G+ +   +   T
Sbjct: 382  VPVENGMAPFFEMKLKHYK-IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYT 438

Query: 3201 VS-DF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT--RATINCYGKGGVYLESLQPDS 3256
            +  D  G   L    +   D G Y   A N  G      R  +    + G    S     
Sbjct: 439  IQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHP 498

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
              +     S     +  P       P F+    D+T + EG+    + ++  +  PDL  
Sbjct: 499  HVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLT-VQEGKLCRMDCKVSGLPTPDLS- 556

Query: 3317 EWFYNGKKL-PHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
             W  +GK + P         + G+  L I      ++G Y C+ATN+ G++S    L   
Sbjct: 557  -WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA 615

Query: 3376 SKE 3378
            +KE
Sbjct: 616  AKE 618



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
           PP   +K +N+ + +G   + + ++ G P P++ W K  + L +S     +   NH    
Sbjct: 622 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 681

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR 377
           L ++   K D+G YT+ A+N  G +  +  L V +      Q  + + +  +  R
Sbjct: 682 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASR 736



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/88 (27%), Positives = 41/88 (46%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+F +  +N   A G   + E ++ G P P + W ++   L         + +  G + 
Sbjct: 622 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 681

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS 158
           LLI+     D G YT +A+N+ G   C+
Sbjct: 682 LLIQGATKEDAGWYTVSAKNEAGIVSCT 709



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 12/123 (9%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS-RFKTYYD-FGF 1234
            PVF++ L N   V++G  + LECR+  +G P  ++ W     S+T  + R   + D  G+
Sbjct: 623  PVFIEKLQNTG-VADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGY 679

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTD-TQNEQAIEQIQLLED 1293
            + L I  AT  D G YTV A N  G      IV    R D+ T   Q  Q+ +  ++   
Sbjct: 680  ICLLIQGATKEDAGWYTVSAKNEAG------IVSCTARLDVYTQWHQQSQSTKPKKVRPS 733

Query: 1294 AAR 1296
            A+R
Sbjct: 734  ASR 736



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 5/101 (4%)

Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
           ++  + P FI  LQ+ G + +G     E ++  V  P  ++ W K+   +T S+   S+ 
Sbjct: 617 KEAHKPPVFIEKLQNTG-VADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMH 673

Query: 824 --NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             N GY+ L I     EDAG YTV A N+ G    TA + V
Sbjct: 674 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 714



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 51/224 (22%), Positives = 95/224 (42%), Gaps = 10/224 (4%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH-DF-GYVALDIIDLIAED 1513
            + EG  V F C++    +   K+ WFK+G+ ++       I  D  G  +L       +D
Sbjct: 401  IFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 458

Query: 1514 SGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEV 1573
             G YT  A N  G    + RL  ++     RS ++ +G   ++    RS+    D  + +
Sbjct: 459  DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR-DSGDENEPI 517

Query: 1574 TTQ--APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE-TN 1630
              +   P    +  ++ ++EG+    + ++  +   T  + W  + KP++  S       
Sbjct: 518  QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP--TPDLSWQLDGKPVRPDSAHKMLVR 575

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674
              G  +L I      D+G YTC A N  G+   S   +V +K++
Sbjct: 576  ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 619



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+ V EG+  +   +++    P + W  +G  + P++    ++ E     L+I      D
Sbjct: 532  DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 591

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             G +TC AT  AGQ   S +LVV +K
Sbjct: 592  AGIYTCIATNRAGQNSFSLELVVAAK 617



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA-TGS 3742
            E+ +  ++ + P   +E   N  V +G PV  +CRV  +G P  +I W         +  
Sbjct: 611  ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTD 668

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            RV    D  G+I L I      DAG YT  A N+ G  + TA++
Sbjct: 669  RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 712



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 4/114 (3%)

Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--F 691
           + PP FI  L++    +G  +  E R+  +G P  +I W K  +S+  S+   S+ +   
Sbjct: 620 HKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNH 677

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745
           GYI L +     +D+G YT  A +  G+    A L V  +   +  S  P+ ++
Sbjct: 678 GYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVR 731



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR-NEKLIEDSSRITKTHD-FGY 2433
            PVF + LQN   + +G     +CR++ V  P  ++ W + NE L   + R++   D  GY
Sbjct: 623  PVFIEKLQNT-GVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 679

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
            + + I     ED G Y   A N  G
Sbjct: 680  ICLLIQGATKEDAGWYTVSAKNEAG 704



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 4/104 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGYV 1768
            PVF   +++  VA+      E R++ V  P+  + W +    +  S    +MH  + GY+
Sbjct: 623  PVFIEKLQNTGVADGYPVRLECRVLGVPPPQ--IFWKKENESLTHSTDRVSMHQDNHGYI 680

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
             L ++    ED+G YT  A NE G    ++ L V ++   Q +S
Sbjct: 681  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQS 724



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE- 4785
            L+   ++EG P  F  ++    KP I W ++G  I    D   I    +    +  T   
Sbjct: 396  LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 455

Query: 4786 -EDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +D G +T  A    G++  + +L+V++
Sbjct: 456  LDDDGNYTIMAANPQGRISCTGRLMVQA 483



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 3/109 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGY 2299
            PP F+ +L+ T  V +G     EC+V  V  P +  +   N     S  R  +  D  GY
Sbjct: 622  PPVFIEKLQNTG-VADGYPVRLECRVLGVPPPQIFWK-KENESLTHSTDRVSMHQDNHGY 679

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPE 2348
            + L IQ    EDAG Y+V A N  G  +    + V  +    S+S +P+
Sbjct: 680  ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPK 728



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 58  RQPITAGRP-GEPSPPIFEQIFK--------NARFAQGGNAKFEGKLRGNPTPVVSWTRK 108
           R+P +  R  G+ + PI E+ F+        +    +G   + + K+ G PTP +SW   
Sbjct: 501 RRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 560

Query: 109 KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
             P+   + + M   E  G  SL+I+ +   D G YTC A N+ G+
Sbjct: 561 GKPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQ 605



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 4/108 (3%)

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD---FQIH 4460
            PV+    P F  K++  ++FE     F     G P P I W+++   I    D    Q  
Sbjct: 383  PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 442

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
               T S+       ++D   +  +A N  G   C+  L+V+   ++GR
Sbjct: 443  LDGTCSLHTTAST-LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR 489



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 10/138 (7%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF- 962
            E+ + P F   +++   + +G     E R+  +G    ++ W K+   +  S+   +   
Sbjct: 618  EAHKPPVFIEKLQNT-GVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQ 674

Query: 963  -NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             N GY+ L I+  T  DAG YT  A N  G  + +A L + T+    ++S  P   +K++
Sbjct: 675  DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP---KKVR 731

Query: 1022 YLEDASRYSKRTEEEVKI 1039
                ASRY+  +++ + I
Sbjct: 732  --PSASRYAALSDQGLDI 747



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 5/98 (5%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHD-FGY 1100
            P F+  L+ T  + +G     E RV         + W    + +T S +R+  + D  GY
Sbjct: 623  PVFIEKLQNTG-VADGYPVRLECRVLGVPP--PQIFWKKENESLTHSTDRVSMHQDNHGY 679

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            + L I     ED+G YTV A+N AG    +A + V T+
Sbjct: 680  ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQ 717



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/107 (24%), Positives = 40/107 (37%)

Query: 52  VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
           V+ SGD              P FE   K+ +  +G    F  ++ GNP P + W +    
Sbjct: 370 VDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 429

Query: 112 LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
           +   + +     +  G  SL        D+G YT  A N  G   C+
Sbjct: 430 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCT 476



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVS 2832
            VFI  L N    +G  +  EC V     P  +I W   N+ L   T   S H  +  Y+ 
Sbjct: 624  VFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYIC 681

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I    +ED+G YT  A N  G  + +  L
Sbjct: 682  LLIQGATKEDAGWYTVSAKNEAGIVSCTARL 712



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 4/110 (3%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S +++ +    E+  PP F     +  +++      ECR++ V     ++ W    + L 
Sbjct: 607  SFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLT 664

Query: 3602 TGS-RVKTIND-FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              + RV    D  G++ L I G  + DAG YT  A N  G  + + +L V
Sbjct: 665  HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 714



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/57 (31%), Positives = 27/57 (47%)

Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            E VV   +A  PPVF+       V +G   R  CRV G P P++ W     ++ + +
Sbjct: 611  ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 667



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 10/162 (6%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFRTF 3472
            +E  K PVF   L N   + +G     E R+     P  ++ W    +SL   + R    
Sbjct: 617  KEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMH 673

Query: 3473 CD-FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT 3531
             D  G++ L I     ED+G Y   A N  G    TA + V  + +   +S  PK +  +
Sbjct: 674  QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPS 733

Query: 3532 IDKIAALEGYSGTVD-TLTPEAESGNPPEFTTTPSDLILSEN 3572
              + AAL      +     PEA   NP   T   + L+ SE+
Sbjct: 734  ASRYAALSDQGLDIKAAFQPEA---NPSHLTLNTA-LVESED 771



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 5/101 (4%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTSND- 1898
            ++ P FI +L   T +++G     ECR+   P P  ++ W   N  +  S  R     D 
Sbjct: 620  HKPPVFIEKLQN-TGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDN 676

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
             G+  L I     ED+G YT  A N  G    + RL+V ++
Sbjct: 677  HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQ 717



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYD-FGYV 2035
            P F + ++N  V +G+PV LE  +  V  P  ++ W      +     R     D  GY+
Sbjct: 623  PVFIEKLQNTGVADGYPVRLECRVLGV--PPPQIFWKKENESLTHSTDRVSMHQDNHGYI 680

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             L I  A  ED G Y   A N  G    T+ + V
Sbjct: 681  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 714



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTVYD-MGF 3886
            PP FI ++++  V +   VR ECRV     P  +I W + N  L  S  R     D  G+
Sbjct: 622  PPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 679

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
            + L I     ED+G Y   A N+ G
Sbjct: 680  ICLLIQGATKEDAGWYTVSAKNEAG 704



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 13/139 (9%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD---Y 1367
            P F   L N    +G  V LECR+  +G    ++ W    + + T    R +   D   Y
Sbjct: 623  PVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESL-THSTDRVSMHQDNHGY 679

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
            + L +     ED+G YT  A N+ G  + SC  R+        +SQ     +K++     
Sbjct: 680  ICLLIQGATKEDAGWYTVSAKNEAG--IVSCTARLDVYTQWHQQSQSTKP-KKVR--PSA 734

Query: 1428 SRYKKTDIIDESVTIKPRF 1446
            SRY    + D+ + IK  F
Sbjct: 735  SRY--AALSDQGLDIKAAF 751


>AF151909-1|AAD34146.1|  404|Homo sapiens CGI-151 protein protein.
          Length = 404

 Score =  196 bits (479), Expect = 1e-48
 Identities = 107/323 (33%), Positives = 173/323 (53%), Gaps = 10/323 (3%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P    K ++ K+ EG    F  +++GNP+P++ WFK+G+++   + H  I      T  +
Sbjct: 22  PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 81

Query: 326 RNTQKS--DSGHYTLLAENPNGCIVTSGYLAVESPTE---SYVQDQRSQYITDTQQRETE 380
             T  +  D G+YT++A NP G I  +G L V++  +   S        ++   + R  +
Sbjct: 82  HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 141

Query: 381 ---ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
              E   I E+   P F++   D  V EGK+ R DC+V+G P P+++W ++ + +R D  
Sbjct: 142 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 201

Query: 438 HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
           HK+LV E+G H+L+I  VT  D+G+ TC+A N++G+ +F   L V  KE    P F+E+ 
Sbjct: 202 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 261

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDG-GASTLDIPRAKA 555
               V +G PV L  R +G P P+I W+K+   +  + + + +H D  G   L I  A  
Sbjct: 262 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 321

Query: 556 SDAAWYQCTAQNVAGSTATRARL 578
            DA WY  +A+N AG  +  ARL
Sbjct: 322 EDAGWYTVSAKNEAGIVSCTARL 344



 Score =  104 bits (250), Expect = 7e-21
 Identities = 79/325 (24%), Positives = 137/325 (42%), Gaps = 28/325 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTL 4571
            P F +  ++  +  G  V    +V G     +YW K+GK++ P   +  ++ D  GT +L
Sbjct: 22   PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 81

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-----------KPQTKAA- 4619
                +   D G Y  +A N  G   C    +V     + +            +P++++  
Sbjct: 82   HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 141

Query: 4620 ----NAP-------PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP-SK 4667
                N P       P  ++   D  V EG+     CK+ G P P + W    K ++P S 
Sbjct: 142  SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 201

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +  + R    ++L I      D G Y C+A N AG+ + + +L V   +       +  L
Sbjct: 202  HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 261

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYE 4785
            ++  V +G P + + ++     P I W +E   +  + D   +H+ N+    LLI    +
Sbjct: 262  QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 321

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
            ED G +T  A   AG V  +A+L V
Sbjct: 322  EDAGWYTVSAKNEAGIVSCTARLDV 346



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 90/354 (25%), Positives = 150/354 (42%), Gaps = 24/354 (6%)

Query: 2940 DPDLKIEWYFNGKVLEQGS-RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +P  KI W+ +GK +   S  + +  D  G  +L        D G YT  A N +G    
Sbjct: 48   NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISC 107

Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQ-QPDDDTGRPPEFTTVFKD 3056
            +  +   + +   +R + P+   G   ++      R    + +P  +    P F     D
Sbjct: 108  TGRLMVQAVN---QRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGD 164

Query: 3057 IVDISEGQIAHYEASL--IPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGMVVLEILG 3112
            +  + EG++   +  +  +PT D S    W  +GK +  +++H++  V   G+  L I  
Sbjct: 165  LT-VQEGKLCRMDCKVSGLPTPDLS----WQLDGKPVRPDSAHKM-LVRENGVHSLIIEP 218

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172
              + D+G Y+C ATN+ GQ   S++L    K   + P F   +QN  G+ DG     EC 
Sbjct: 219  VTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN-TGVADGYPVRLECR 277

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHST-RIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
            V+ V  P  +I W    + + HST R+    D  G++ L I      D+G Y   A N+ 
Sbjct: 278  VLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 335

Query: 3231 GEDFTRATINCYGKGGVYLESLQPDSL---AKIRELESLQGAQQQTPSTPSAEP 3281
            G     A ++ Y +     +S +P  +   A      S QG   +    P A P
Sbjct: 336  GIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANP 389



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 63/236 (26%), Positives = 101/236 (42%), Gaps = 9/236 (3%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA-SNRLTTMHDF-GY 1767
            AP F M +K  ++ E     F  R+   G+PK ++ W ++G  I   S+  T   D  G 
Sbjct: 21   APFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 78

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L+      +D G YT  A N  G    +  L VQ+        +  S    +++    
Sbjct: 79   CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 138

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887
            SR    E+  +          Q  G   + EG+    +C++   P P++   W  +GK +
Sbjct: 139  SRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKPV 196

Query: 1888 Q--SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            +  S H+     + G  +L I  V   D+G YTC A N  GQ   S+ L V +KE+
Sbjct: 197  RPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 251



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 11/234 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--FGYI 694
           P F + LK     EG  + F  R+   G+P  KI W K+G+ I   S   +I R   G  
Sbjct: 22  PFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 79

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
           SL   +  + D G YT  A +  G       L V       R+ + P    ++++    S
Sbjct: 80  SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 139

Query: 755 K--YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
           +      E I+E+   RP F++   DL  +QEG+    + +++ +  PT  + W  DG+P
Sbjct: 140 RDSGDENEPIQERFF-RPHFLQAPGDL-TVQEGKLCRMDCKVSGL--PTPDLSWQLDGKP 195

Query: 813 ITA-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           +   S+    +   G  SL I  + + DAG YT  A N+ G+   +  + VAA+
Sbjct: 196 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 249



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 55/192 (28%), Positives = 80/192 (41%), Gaps = 8/192 (4%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILI 4469
            P F +      V E +  R + +  G P P + W  +  P++ +S    +   +    LI
Sbjct: 156  PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 215

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I  V   D+ ++  +A NR G    S  LVV  K         PP F    QN  V  G 
Sbjct: 216  IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-----PPVFIEKLQNTGVADGY 270

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYECV 4587
             VRL+ +V G  P  ++W K  + +        + +D  G   LLI  A  +D+G Y   
Sbjct: 271  PVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVS 330

Query: 4588 AINSAGEARCDA 4599
            A N AG   C A
Sbjct: 331  AKNEAGIVSCTA 342



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 68/225 (30%), Positives = 100/225 (44%), Gaps = 14/225 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN-DF-GF 3752
            P F +++K +  + EG PV F CRV   G+P  +I WF +G+  +  S  +T+  D  G 
Sbjct: 22   PFFEMKLK-HYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 78

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
             +L        D G YT  A N  G  + T ++   A   +    + P+  SG       
Sbjct: 79   CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQA---VNQRGRSPRSPSGHPHVRRP 135

Query: 3813 RGRISDAPKE-EPIVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
            R R  D+  E EPI      P F+      TV+E +  R +C+V     P L   W  +G
Sbjct: 136  RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDG 193

Query: 3870 K-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            K + P       V + G  SL I  V + D+G Y C A N  G++
Sbjct: 194  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 238



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 70/242 (28%), Positives = 103/242 (42%), Gaps = 15/242 (6%)

Query: 3417 GKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC-DF 3475
            G AP F + L + + + EG    F  R+    +P  K+ W+ +GK +   S   T   D 
Sbjct: 19   GMAPFFEMKLKHYK-IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDL 75

Query: 3476 -GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDK 3534
             G   L  + +  +D G Y   A N  G    T  + VQ         + P G    + +
Sbjct: 76   DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG-HPHVRR 134

Query: 3535 IAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVE 3592
              +    SG  D   P  E    P F   P DL + E      +C++  +P  D S    
Sbjct: 135  PRSRSRDSG--DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLS---- 188

Query: 3593 WFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            W  +GKP+   S  K  + + G   L I  V  RDAG+YTC ATNR G+ + S +L V  
Sbjct: 189  WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAA 248

Query: 3652 RQ 3653
            ++
Sbjct: 249  KE 250



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 90/358 (25%), Positives = 144/358 (40%), Gaps = 50/358 (13%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KTGHRFRPAYEFDY 1367
            AP F   L + +  EG  V   CR+   G+   ++ WF +GK I  K+ H +    + D 
Sbjct: 21   APFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDH-YTIQRDLDG 77

Query: 1368 V-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426
              +L   +   +D G YT  A N  G    +  L V A        + PSG   ++    
Sbjct: 78   TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 137

Query: 1427 TSRYK--KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484
             SR    + + I E    +P F+  P  +  V EG+    +CK+  +   +L   W  +G
Sbjct: 138  RSRDSGDENEPIQERF-FRPHFLQAPGDL-TVQEGKLCRMDCKVSGLPTPDLS--WQLDG 193

Query: 1485 QPVTIGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            +PV      +  + + G  +L I  + + D+GIYTC A N                    
Sbjct: 194  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATN-------------------- 233

Query: 1544 RSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIP 1603
            R+ QN   LE +   ++  K              P+    L+N  + +G     E R++ 
Sbjct: 234  RAGQNSFSLELVVAAKEAHK-------------PPVFIEKLQNTGVADGYPVRLECRVLG 280

Query: 1604 VSDATLKVEWYHNNKPLK-SGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            V     ++ W   N+ L  S  R +   +N G++ L I     ED+G YT  A N  G
Sbjct: 281  VPPP--QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 336



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 69/273 (25%), Positives = 110/273 (40%), Gaps = 17/273 (6%)

Query: 765  QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824
            +T   P F   L+   ++ EG    F  ++    +P  ++ W+KDG+ I+  S   +I  
Sbjct: 17   KTGMAPFFEMKLKHY-KIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQR 73

Query: 825  F--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIE 882
               G  SL+      +D G+YT+ A N  G    T  + V A +        P    ++ 
Sbjct: 74   DLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVR 133

Query: 883  KTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLR 942
            +                  + E   +P F     D ++++EG     + ++   G  T  
Sbjct: 134  RPRSRSRDSGDENEP----IQERFFRPHFLQAPGD-LTVQEGKLCRMDCKVS--GLPTPD 186

Query: 943  VEWLKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W  DG+PV   S         G  +L I+ VT  DAG YTC A N  GQ + S  L +
Sbjct: 187  LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 246

Query: 1002 VTKKDIIAESQHPGGLEKIQYLEDASRYSKRTE 1034
              K+      + P  +EK+Q    A  Y  R E
Sbjct: 247  AAKE----AHKPPVFIEKLQNTGVADGYPVRLE 275



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 64/241 (26%), Positives = 102/241 (42%), Gaps = 11/241 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN-D 3611
            ++G  P F        + E     F CR+    +   ++ WF +GK +   S   TI  D
Sbjct: 17   KTGMAPFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRD 74

Query: 3612 F-GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTE 3670
              G   L        D G YT  A N  G  + + +L V+        P+ PS       
Sbjct: 75   LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 134

Query: 3671 SIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRID 3730
               +  ++  + E I    E+   P F ++   ++ V EG     DC+V   G PT  + 
Sbjct: 135  PRSRSRDSGDENEPI---QERFFRPHF-LQAPGDLTVQEGKLCRMDCKVS--GLPTPDLS 188

Query: 3731 WFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
            W  +G+P    S    L  + G  +L I+ + +RDAG YTC ATN+ G  + + ++  +A
Sbjct: 189  WQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAA 248

Query: 3790 K 3790
            K
Sbjct: 249  K 249



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 57/211 (27%), Positives = 91/211 (43%), Gaps = 11/211 (5%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA-RFHITFDF-GYVSLDIQHCVPED 2311
            +FEG    F C+V    +P  +I ++ +GK +   +  + I  D  G  SL       +D
Sbjct: 33   IFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 90

Query: 2312 AGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPV 2371
             G Y++ A N  G  +    + V A        + P G   +R   S       E  EP+
Sbjct: 91   DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDE-NEPI 149

Query: 2372 TRQ--RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-DSSRITKT 2428
              +  RP F Q   ++  +QEG+    DC++   G PT  + W  + K +  DS+     
Sbjct: 150  QERFFRPHFLQAPGDL-TVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLV 206

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             + G  S+ I  V   D G+Y C A+N  G+
Sbjct: 207  RENGVHSLIIEPVTSRDAGIYTCIATNRAGQ 237



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 59/238 (24%), Positives = 104/238 (43%), Gaps = 12/238 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DF-GFVALDIIHATSAD 1246
            + EG  +   CR+   G+P  ++ WF +G+ ++  S   T   D  G  +L    +T  D
Sbjct: 33   IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 90

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT 1306
             G YT+ A N  G    +  + V   +      ++      ++     +R +    E I 
Sbjct: 91   DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 150

Query: 1307 V-MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
                 P F +A  ++   EG    ++C++   G  T  + W  +GKP++     +     
Sbjct: 151  ERFFRPHFLQAPGDLTVQEGKLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLVRE 208

Query: 1366 DYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            + V +L +  V   D+G+YTC ATN+ G+   S  L V AK+      + P  +EK+Q
Sbjct: 209  NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE----AHKPPVFIEKLQ 262



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 58/224 (25%), Positives = 96/224 (42%), Gaps = 11/224 (4%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYV-SLDITHTYEEDSG 2844
            EG  + F C V  + +P  KI WF + K + P    Y    D     SL  T +  +D G
Sbjct: 35   EGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 92

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904
             YT  A N +G  + +G L     + +    + P+  +G   V +        G      
Sbjct: 93   NYTIMAANPQGRISCTGRLMV---QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPI 149

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK-LT 2963
               + +P + +    +  + EG++  ++ +V     PDL   W  +GK +   S  K L 
Sbjct: 150  QERFFRPHF-LQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKPVRPDSAHKMLV 206

Query: 2964 SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
             + G  +L +  V  RD+GIYTC A N+ G+   S  +   +K+
Sbjct: 207  RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 250



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 12/225 (5%)

Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS-RITKTHD 2430
            T   P F   L++   I EG    F CR+   G+P  K+ WF++ K I   S   T   D
Sbjct: 18   TGMAPFFEMKLKHY-KIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQISPKSDHYTIQRD 74

Query: 2431 F-GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQK 2489
              G  S+  +    +D+G Y   A+N  G                    + P G   +++
Sbjct: 75   LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 134

Query: 2490 LEQPHERRSEE--PDRE-FEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYI 2546
                     +E  P +E F +P F Q   G   + EG+    + +V  +  P L   W +
Sbjct: 135  PRSRSRDSGDENEPIQERFFRPHFLQA-PGDLTVQEGKLCRMDCKVSGLPTPDL--SWQL 191

Query: 2547 NGVELKMGSRFRT-THDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +G  ++  S  +    + G  +L I  V + DAG+Y C A NRAG
Sbjct: 192  DGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAG 236



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 61/239 (25%), Positives = 103/239 (43%), Gaps = 16/239 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF--GY 966
            P F+  +K    I EG    F  R+   G+   ++ W KDG+ +   S   T      G 
Sbjct: 22   PFFEMKLK-HYKIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 78

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDA 1026
             +L   + T+ D G+YT  A N  G+ + +  L +          + P G   ++     
Sbjct: 79   CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 138

Query: 1027 SRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNG 1083
            SR S    E ++    +P FL    G   + EG+    + +V   P  DL+    W  +G
Sbjct: 139  SRDSGDENEPIQERFFRPHFL-QAPGDLTVQEGKLCRMDCKVSGLPTPDLS----WQLDG 193

Query: 1084 KQIT--SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
            K +   SA+++    + G  +L I  V + D+G+YT +A N AG+   S  + V  + +
Sbjct: 194  KPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 251



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 70/295 (23%), Positives = 123/295 (41%), Gaps = 22/295 (7%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDF-GYV 2035
            P F   +K+ ++ EG PV    T     +P  ++ W+ +G+ +  +   +    D  G  
Sbjct: 22   PFFEMKLKHYKIFEGMPVTF--TCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 79

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA-----KSGLYLDTLDEQRLKKIQE 2090
            +L    +  +D G Y   A N  G    T  + V A     +S          R  + + 
Sbjct: 80   SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 139

Query: 2091 LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQ 2150
             +  +  +PI+E     RP FL A   L  ++EG     +C+V  +  P L+  W  +G+
Sbjct: 140  RDSGDENEPIQERF--FRPHFLQAPGDL-TVQEGKLCRMDCKVSGLPTPDLS--WQLDGK 194

Query: 2151 KIRAGHRYRT-THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
             +R    ++    + G  +L I    + D+G Y C ATN+ G+   +  L VA       
Sbjct: 195  PVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---- 250

Query: 2210 DTQHPNGLEKIRQL-EAQGHSTRIEVEEPKISPPR--FVTELRGTTHVFEGKTAH 2261
              + P  +EK++    A G+  R+E     + PP+  +  E    TH  +  + H
Sbjct: 251  AHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 305



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 62/237 (26%), Positives = 99/237 (41%), Gaps = 11/237 (4%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDF 2164
            G  P F   L   + + EG    F CRV    +P   I WF +G++I      Y    D 
Sbjct: 19   GMAPFFEMKLKHYK-IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDL 75

Query: 2165 -GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL 2223
             G  +L    +  +D G Y   A N  G    T  L V          + P+G   +R+ 
Sbjct: 76   DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRP 135

Query: 2224 EAQGHSTRIEVE--EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHN 2281
             ++   +  E E  + +   P F+ +  G   V EGK    +C+V  +  P+L  +   +
Sbjct: 136  RSRSRDSGDENEPIQERFFRPHFL-QAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL--D 192

Query: 2282 GKALQ-SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
            GK ++  +A   +  + G  SL I+     DAG Y+  A N  G  + ++ + V AK
Sbjct: 193  GKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 249



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 51/219 (23%), Positives = 92/219 (42%), Gaps = 30/219 (13%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLR 324
           P   Q P +  +QEG   +   ++SG P P ++W  +G+ +   + H+++   N   +L 
Sbjct: 156 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 215

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +      D+G YT        CI T+      +   S+                 E  + 
Sbjct: 216 IEPVTSRDAGIYT--------CIATN-----RAGQNSF---------------SLELVVA 247

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
             E    P F++  Q+  V +G   R +CRV G P P++ W   +  +    +   +  +
Sbjct: 248 AKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 307

Query: 445 S-GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           + G   L+I   T  D+G  T  A+N++G  +   RL+V
Sbjct: 308 NHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 346



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 15/228 (6%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA---RLKSTFDF 2697
            AP F   LK Y K+ EG  V    +V     P  KI WFK+G  ++  +    ++   D 
Sbjct: 21   APFFEMKLKHY-KIFEGMPVTFTCRVAGNPKP--KIYWFKDGKQISPKSDHYTIQRDLD- 76

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL----LGESLHPDSLDRI 2753
            G  +L   +   DD G YT  A N  G    T  + ++  +         S HP  + R 
Sbjct: 77   GTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH-VRRP 135

Query: 2754 GALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN 2813
             +                    F+    ++  +EG     +C V  S  PT  + W  + 
Sbjct: 136  RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV--SGLPTPDLSWQLDG 193

Query: 2814 KPLPSGTRYKS-THDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
            KP+   + +K    +    SL I      D+GIYTC ATN  G  + S
Sbjct: 194  KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS 241



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 64/250 (25%), Positives = 106/250 (42%), Gaps = 21/250 (8%)

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK- 3870
            ER R +DA   +      P F  ++K + + E   V F CRV    +PK +I W+++GK 
Sbjct: 6    ERSRTADAASWK--TGMAPFFEMKLKHYKIFEGMPVTFTCRV--AGNPKPKIYWFKDGKQ 61

Query: 3871 LLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
            + P    Y    D+ G  SL       +D G Y   A N  G       ISC     +  
Sbjct: 62   ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGR------ISCTGRLMVQA 115

Query: 3930 QNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKK-QPPRFVTQIQSQTSLVEM 3988
             NQ  RG  RS         +++  S    + D+   + ++   P F+ Q     ++ E 
Sbjct: 116  VNQ--RG--RSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFL-QAPGDLTVQEG 170

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTP-IYDFGYVAMNFGWVYPEDSGEYL 4047
            +  + +C+++  G P   + W  +GKP+   +     + + G  ++    V   D+G Y 
Sbjct: 171  KLCRMDCKVS--GLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYT 228

Query: 4048 CRATNLYGMD 4057
            C ATN  G +
Sbjct: 229  CIATNRAGQN 238



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE-SGNH 448
           +AP F    +   + EG    F CRV G P P++ WF + +QI    +H  +  +  G  
Sbjct: 20  MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 79

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           +L  T  TL D G  T +A N  G  +   RL V
Sbjct: 80  SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 113



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 15/193 (7%)

Query: 3993 FECQLAPVGDPNMKVEWFFNGKPLLHKN-RFTPIYDF-GYVAMNFGWVYPEDSGEYLCRA 4050
            F C++A  G+P  K+ WF +GK +  K+  +T   D  G  +++      +D G Y   A
Sbjct: 41   FTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMA 98

Query: 4051 TNLYGMDETKAVIKTTGK---PGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKA 4107
             N  G       I  TG+     +    + P+       +R   +  + + ++     + 
Sbjct: 99   ANPQGR------ISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 152

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMY 4165
               P F+  P  +TV+EG+  R  C+V+G P P + W L+G  +   S +K+    +G++
Sbjct: 153  FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 212

Query: 4166 HFDIPKTRQYDTG 4178
               I      D G
Sbjct: 213  SLIIEPVTSRDAG 225



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 59/235 (25%), Positives = 87/235 (37%), Gaps = 23/235 (9%)

Query: 489 VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTD-GGAS 546
           +AP F  +     + EG PV    R  G P P+I W KDG  I P  +   I  D  G  
Sbjct: 20  MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 79

Query: 547 TLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXX 606
           +L    +   D   Y   A N  G  +   RL            +R   PR         
Sbjct: 80  SLHTTASTLDDDGNYTIMAANPQGRISCTGRL------MVQAVNQRGRSPR--------- 124

Query: 607 XXXXXXXYLRHVERARPYIPPGE--EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVG 664
                    R   R+R      E  ++R +  P F+     +T  EG     + ++   G
Sbjct: 125 SPSGHPHVRRPRSRSRDSGDENEPIQERFF-RPHFLQAPGDLTVQEGKLCRMDCKVS--G 181

Query: 665 DPTMKIEWLKNGQSIEASSRFTSIFR-FGYISLDMLSLNIQDSGEYTCRAVSATG 718
            PT  + W  +G+ +   S    + R  G  SL +  +  +D+G YTC A +  G
Sbjct: 182 LPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAG 236



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 2/123 (1%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            KPP+F +K+Q   V +    R E    G P P I W +EN  + +S D   +H  +   I
Sbjct: 253  KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 312

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L+I+    ED+  +   A+N  G   C+A L V  +  Q      P     +A      
Sbjct: 313  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAAL 372

Query: 4527 SGQ 4529
            S Q
Sbjct: 373  SDQ 375



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 54/238 (22%), Positives = 91/238 (38%), Gaps = 11/238 (4%)

Query: 3146 GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS-DF 3204
            G  P F   +++ + + +G    F C V    +P  KI W+ +G+ +   +   T+  D 
Sbjct: 19   GMAPFFEMKLKHYK-IFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRDL 75

Query: 3205 -GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT--RATINCYGKGGVYLESLQPDSLAKIR 3261
             G   L    +   D G Y   A N  G      R  +    + G    S       +  
Sbjct: 76   DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRP 135

Query: 3262 ELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321
               S     +  P       P F+    D+T + EG+    + ++  +  PDL   W  +
Sbjct: 136  RSRSRDSGDENEPIQERFFRPHFLQAPGDLT-VQEGKLCRMDCKVSGLPTPDLS--WQLD 192

Query: 3322 GKKL-PHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            GK + P         + G+  L I      ++G Y C+ATN+ G++S    L   +KE
Sbjct: 193  GKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 250



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
           PP   +K +N+ + +G   + + ++ G P P++ W K  + L +S     +   NH    
Sbjct: 254 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 313

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR 377
           L ++   K D+G YT+ A+N  G +  +  L V +      Q  + + +  +  R
Sbjct: 314 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASR 368



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/88 (27%), Positives = 41/88 (46%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+F +  +N   A G   + E ++ G P P + W ++   L         + +  G + 
Sbjct: 254 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 313

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS 158
           LLI+     D G YT +A+N+ G   C+
Sbjct: 314 LLIQGATKEDAGWYTVSAKNEAGIVSCT 341



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 12/123 (9%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS-RFKTYYD-FGF 1234
            PVF++ L N   V++G  + LECR+  +G P  ++ W     S+T  + R   + D  G+
Sbjct: 255  PVFIEKLQNTG-VADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGY 311

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTD-TQNEQAIEQIQLLED 1293
            + L I  AT  D G YTV A N  G      IV    R D+ T   Q  Q+ +  ++   
Sbjct: 312  ICLLIQGATKEDAGWYTVSAKNEAG------IVSCTARLDVYTQWHQQSQSTKPKKVRPS 365

Query: 1294 AAR 1296
            A+R
Sbjct: 366  ASR 368



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 5/101 (4%)

Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
           ++  + P FI  LQ+ G + +G     E ++  V  P  ++ W K+   +T S+   S+ 
Sbjct: 249 KEAHKPPVFIEKLQNTG-VADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMH 305

Query: 824 --NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             N GY+ L I     EDAG YTV A N+ G    TA + V
Sbjct: 306 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 346



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 56/251 (22%), Positives = 104/251 (41%), Gaps = 11/251 (4%)

Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488
            R +  D       + P F  + K  + + EG  V F C++    +   K+ WFK+G+ ++
Sbjct: 7    RSRTADAASWKTGMAPFFEMKLKHYK-IFEGMPVTFTCRV--AGNPKPKIYWFKDGKQIS 63

Query: 1489 IGHRFRPIH-DF-GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST 1546
                   I  D  G  +L       +D G YT  A N  G    + RL  ++     RS 
Sbjct: 64   PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 123

Query: 1547 QNEAGLEQIQVLEDRSKYHRTDMVDEVTTQ--APICTTSLKNVEIKEGQRAHFERRLIPV 1604
            ++ +G   ++    RS+    D  + +  +   P    +  ++ ++EG+    + ++  +
Sbjct: 124  RSPSGHPHVRRPRSRSR-DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGL 182

Query: 1605 SDATLKVEWYHNNKPLKSGSRFTE-TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT 1663
               T  + W  + KP++  S         G  +L I      D+G YTC A N  G+   
Sbjct: 183  P--TPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSF 240

Query: 1664 SGIAIVHSKKS 1674
            S   +V +K++
Sbjct: 241  SLELVVAAKEA 251



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDFQMIHEGNNAVLLIGNTYEED 4787
            D+ V EG+  +   +++    P + W  +G  + P++    ++ E     L+I      D
Sbjct: 164  DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 223

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             G +TC AT  AGQ   S +LVV +K
Sbjct: 224  AGIYTCIATNRAGQNSFSLELVVAAK 249



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA-TGS 3742
            E+ +  ++ + P   +E   N  V +G PV  +CRV  +G P  +I W         +  
Sbjct: 243  ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTD 300

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            RV    D  G+I L I      DAG YT  A N+ G  + TA++
Sbjct: 301  RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 344



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 4/114 (3%)

Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--F 691
           + PP FI  L++    +G  +  E R+  +G P  +I W K  +S+  S+   S+ +   
Sbjct: 252 HKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNH 309

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745
           GYI L +     +D+G YT  A +  G+    A L V  +   +  S  P+ ++
Sbjct: 310 GYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVR 363



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR-NEKLIEDSSRITKTHD-FGY 2433
            PVF + LQN   + +G     +CR++ V  P  ++ W + NE L   + R++   D  GY
Sbjct: 255  PVFIEKLQNT-GVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 311

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
            + + I     ED G Y   A N  G
Sbjct: 312  ICLLIQGATKEDAGWYTVSAKNEAG 336



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 4/104 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGYV 1768
            PVF   +++  VA+      E R++ V  P+  + W +    +  S    +MH  + GY+
Sbjct: 255  PVFIEKLQNTGVADGYPVRLECRVLGVPPPQ--IFWKKENESLTHSTDRVSMHQDNHGYI 312

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
             L ++    ED+G YT  A NE G    ++ L V ++   Q +S
Sbjct: 313  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQS 356



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE- 4785
            L+   ++EG P  F  ++    KP I W ++G  I    D   I    +    +  T   
Sbjct: 28   LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 87

Query: 4786 -EDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +D G +T  A    G++  + +L+V++
Sbjct: 88   LDDDGNYTIMAANPQGRISCTGRLMVQA 115



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 3/109 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGY 2299
            PP F+ +L+ T  V +G     EC+V  V  P +  +   N     S  R  +  D  GY
Sbjct: 254  PPVFIEKLQNTG-VADGYPVRLECRVLGVPPPQIFWK-KENESLTHSTDRVSMHQDNHGY 311

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPE 2348
            + L IQ    EDAG Y+V A N  G  +    + V  +    S+S +P+
Sbjct: 312  ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPK 360



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 58  RQPITAGRP-GEPSPPIFEQIFK--------NARFAQGGNAKFEGKLRGNPTPVVSWTRK 108
           R+P +  R  G+ + PI E+ F+        +    +G   + + K+ G PTP +SW   
Sbjct: 133 RRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 192

Query: 109 KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
             P+   + + M   E  G  SL+I+ +   D G YTC A N+ G+
Sbjct: 193 GKPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQ 237



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 10/138 (7%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF- 962
            E+ + P F   +++   + +G     E R+  +G    ++ W K+   +  S+   +   
Sbjct: 250  EAHKPPVFIEKLQNT-GVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQ 306

Query: 963  -NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             N GY+ L I+  T  DAG YT  A N  G  + +A L + T+    ++S  P   +K++
Sbjct: 307  DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP---KKVR 363

Query: 1022 YLEDASRYSKRTEEEVKI 1039
                ASRY+  +++ + I
Sbjct: 364  --PSASRYAALSDQGLDI 379



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 5/98 (5%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHD-FGY 1100
            P F+  L+ T  + +G     E RV         + W    + +T S +R+  + D  GY
Sbjct: 255  PVFIEKLQNTG-VADGYPVRLECRVLGVPP--PQIFWKKENESLTHSTDRVSMHQDNHGY 311

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            + L I     ED+G YTV A+N AG    +A + V T+
Sbjct: 312  ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQ 349



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/106 (24%), Positives = 43/106 (40%), Gaps = 4/106 (3%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD---FQIHTF 4462
            K    P F  K++  ++FE     F     G P P I W+++   I    D    Q    
Sbjct: 17   KTGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLD 76

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
             T S+       ++D   +  +A N  G   C+  L+V+   ++GR
Sbjct: 77   GTCSLHTTAST-LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR 121



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVS 2832
            VFI  L N    +G  +  EC V     P  +I W   N+ L   T   S H  +  Y+ 
Sbjct: 256  VFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYIC 313

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I    +ED+G YT  A N  G  + +  L
Sbjct: 314  LLIQGATKEDAGWYTVSAKNEAGIVSCTARL 344



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/87 (25%), Positives = 35/87 (40%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P FE   K+ +  +G    F  ++ GNP P + W +    +   + +     +  G  SL
Sbjct: 22  PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 81

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICS 158
                   D+G YT  A N  G   C+
Sbjct: 82  HTTASTLDDDGNYTIMAANPQGRISCT 108



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 4/110 (3%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S +++ +    E+  PP F     +  +++      ECR++ V     ++ W    + L 
Sbjct: 239  SFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLT 296

Query: 3602 TGS-RVKTIND-FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              + RV    D  G++ L I G  + DAG YT  A N  G  + + +L V
Sbjct: 297  HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 346



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/57 (31%), Positives = 27/57 (47%)

Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            E VV   +A  PPVF+       V +G   R  CRV G P P++ W     ++ + +
Sbjct: 243  ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 299



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 10/162 (6%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFRTF 3472
            +E  K PVF   L N   + +G     E R+     P  ++ W    +SL   + R    
Sbjct: 249  KEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMH 305

Query: 3473 CD-FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT 3531
             D  G++ L I     ED+G Y   A N  G    TA + V  + +   +S  PK +  +
Sbjct: 306  QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPS 365

Query: 3532 IDKIAALEGYSGTVD-TLTPEAESGNPPEFTTTPSDLILSEN 3572
              + AAL      +     PEA   NP   T   + L+ SE+
Sbjct: 366  ASRYAALSDQGLDIKAAFQPEA---NPSHLTLNTA-LVESED 403



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 5/101 (4%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTSND- 1898
            ++ P FI +L   T +++G     ECR+   P P  ++ W   N  +  S  R     D 
Sbjct: 252  HKPPVFIEKLQN-TGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDN 308

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
             G+  L I     ED+G YT  A N  G    + RL+V ++
Sbjct: 309  HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQ 349



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYD-FGYV 2035
            P F + ++N  V +G+PV LE  +  V  P  ++ W      +     R     D  GY+
Sbjct: 255  PVFIEKLQNTGVADGYPVRLECRVLGV--PPPQIFWKKENESLTHSTDRVSMHQDNHGYI 312

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             L I  A  ED G Y   A N  G    T+ + V
Sbjct: 313  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 346



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTVYD-MGF 3886
            PP FI ++++  V +   VR ECRV     P  +I W + N  L  S  R     D  G+
Sbjct: 254  PPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 311

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
            + L I     ED+G Y   A N+ G
Sbjct: 312  ICLLIQGATKEDAGWYTVSAKNEAG 336



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 13/139 (9%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD---Y 1367
            P F   L N    +G  V LECR+  +G    ++ W    + + T    R +   D   Y
Sbjct: 255  PVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESL-THSTDRVSMHQDNHGY 311

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
            + L +     ED+G YT  A N+ G  + SC  R+        +SQ     +K++     
Sbjct: 312  ICLLIQGATKEDAGWYTVSAKNEAG--IVSCTARLDVYTQWHQQSQSTKP-KKVR--PSA 366

Query: 1428 SRYKKTDIIDESVTIKPRF 1446
            SRY    + D+ + IK  F
Sbjct: 367  SRY--AALSDQGLDIKAAF 383



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 13/28 (46%), Positives = 17/28 (60%)

Query: 4124 EGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            EG    F CRV G+PKP++ W  +G  I
Sbjct: 35   EGMPVTFTCRVAGNPKPKIYWFKDGKQI 62


>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
            polypeptide kinase isoform 2 protein.
          Length = 1845

 Score =  176 bits (428), Expect = 2e-42
 Identities = 185/750 (24%), Positives = 299/750 (39%), Gaps = 58/750 (7%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGE 4045
            E  T KFE ++   G P  +V W  NG+P+    RF       G  ++    V+ ED G+
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 4046 YLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEES 4105
            Y C ATN  G  +    +   G     +  QL + + S        AS   T   +  E 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE- 158

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGM 4164
               CPP F +    V V+EG+  RF C++TG P+P+V WL     +   +R  ++  +GM
Sbjct: 159  ---CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGM 215

Query: 4165 YHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQY 4224
               +I    Q D G    +             L +       +G L +A R +  ET   
Sbjct: 216  QVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI-------QG-LDSANRSFVRET--- 264

Query: 4225 QRTETELEKTFEERQVLQRQGVIDH-RPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE 4283
            + T +++ K  E   V+ ++  +D      K K    P+             +     +E
Sbjct: 265  KATNSDVRK--EVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ---PPRE 319

Query: 4284 LENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQ 4343
             + E      R    T         +T    A+   +     L       E+R +    +
Sbjct: 320  SKLESCKDSPRTAPQTPVLQKTSSSITLQA-ARVQPEPRAPGLGVLSPSGEERKRPAPPR 378

Query: 4344 KPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEG 4403
                P           V  A  ++   E   D    +  +  ++ E++   QT +   EG
Sbjct: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKEN-QTVKFRCEG 437

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
                   P F+  ++ C V E +    +    G P+P I W     PI+ +   +    +
Sbjct: 438  LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEA 494

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG-IVP--------P 4514
              + L I+    ED   +  +AEN  G   CSA + V EK+   +   ++P        P
Sbjct: 495  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLI 4573
             F     ++ V  G  V +  +V+G  P +V WL NG ++Q +  +   E+ GT ++L I
Sbjct: 555  IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLCI 613

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
             E +P+D+G Y C A NSAGE R  A   V       +P   T+     P  I   +   
Sbjct: 614  QEVFPEDTGTYTCEAWNSAGEVRTQAVLTV------QEPHDGTQ-----PWFISKPRSVT 662

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             + GQ++  SC I G P PTV W + G  L K + +F++ +  D +TL + +  P   G 
Sbjct: 663  ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
            Y+ +  N  G  +    L + Q   A  LP
Sbjct: 723  YEILLKNRVGECSCQVSL-MLQNSSARALP 751



 Score =  143 bits (346), Expect = 2e-32
 Identities = 163/650 (25%), Positives = 263/650 (40%), Gaps = 59/650 (9%)

Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFG 1633
            T+AP      +N+ IKEG  A FE R+    +   +V W+ N +P+ SG RF  +    G
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 1634 FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLED 1693
              +L I +   ED G YTC A N  G    +    V    +  L  Q   +    ++   
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQL-GQPVVSKTLGDRFSA 146

Query: 1694 TSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753
            ++   R S   E     P F   +  + V E Q   F  ++   G P+ +V WL+  VP+
Sbjct: 147  SAVETRPSIWGEC---PPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPL 201

Query: 1754 EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ----SKASLQ 1809
            + S R++     G   L +  VN +D G YTC  +N  G+A  S+ L +Q    +  S  
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261

Query: 1810 LESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNG-PTKLSEGQ------SA 1862
             E++  ++  + +     S+  + + +E A         Q  G P   +  Q      S 
Sbjct: 262  RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321

Query: 1863 HYECRIEPYPDPNMRVEWYFNGKV-LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
               C+  P   P   V    +  + LQ+    R   +     L +L+  GE+        
Sbjct: 322  LESCKDSPRTAPQTPVLQKTSSSITLQAA---RVQPEPRAPGLGVLSPSGEERKRPAPPR 378

Query: 1922 INNLGQAVSSI-RLNVQSKES---IIRDSQHESALEKI------QYLEDDSRYKRAVQDD 1971
                      +   +V SK +   I  + Q +SA  K       Q ++++   K   +  
Sbjct: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGL 438

Query: 1972 SFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031
            + +   P F   +K+  V EG    L+ ++     P  R+ W  NG+P+Q     ++T +
Sbjct: 439  AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCE 493

Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQEL 2091
             G   L I  A  ED GTY C A NA+G+   ++ V V  K                +  
Sbjct: 494  AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK----------------KSS 537

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
             K E   P+   +P   P+FL  L+   +LK  D +     V+   +P   + W HNG +
Sbjct: 538  RKSEYLLPVAPSKP-TAPIFLQGLS---DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593

Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            I+    +         +L I   + ED+GTY C+A N  GE      L V
Sbjct: 594  IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score =  131 bits (317), Expect = 5e-29
 Identities = 86/307 (28%), Positives = 135/307 (43%), Gaps = 7/307 (2%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V PSF+   ++  V  GQ   L   V GT    + WL NG+ +Q   R+    E G   L
Sbjct: 443  VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTC--EAGVAEL 499

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK---PQTKAANAPPEIIEP 4628
             I +A P+D G Y C+A N+ G+  C A   V    +  K +   P   +    P  ++ 
Sbjct: 500  HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L D  V +G  +  + ++ G P P V W      I+ S+ F   +   +++L I E FPE
Sbjct: 560  LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            D G Y C A+NSAG V   A L V +P        ++  R +    GQ       I    
Sbjct: 620  DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 679

Query: 4749 KPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             PT+ WLR+G AL  +T  F+++   +   L++        G +        G+      
Sbjct: 680  FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739

Query: 4808 LVVKSKT 4814
            L++++ +
Sbjct: 740  LMLQNSS 746



 Score =  109 bits (261), Expect = 3e-22
 Identities = 78/314 (24%), Positives = 129/314 (41%), Gaps = 19/314 (6%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P  +   ++  + EG D   Q  + G P PR+TW  NGQ +  +             L +
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHI 501

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
           ++    D G YT LAEN  G +  S ++ V     S    ++S+Y+              
Sbjct: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----RKSEYLLPVAP--------- 548

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
             K  AP F++   D  V +G       +V+G P PEV W  N  +I++  +        
Sbjct: 549 -SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRG 606

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
             H+L I  V   D+G  TC A N +GE   Q  L V E      P F+ +  ++    G
Sbjct: 607 TQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLG 666

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           + V+++    G P P + W +DG  +  +     +  +    TL + + +   A  Y+  
Sbjct: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 726

Query: 565 AQNVAGSTATRARL 578
            +N  G  + +  L
Sbjct: 727 LKNRVGECSCQVSL 740



 Score =  107 bits (258), Expect = 7e-22
 Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 14/235 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-G 3476
            +AP F +P  N+  ++EG  A FE R+    +P  +V W+ NG+ + +G RF   C   G
Sbjct: 31   EAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 3477 FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIA 3536
               L I   + ED G+Y C A N  G    T  + V+G        QL + +   + K  
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPV---VSKTL 140

Query: 3537 ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
                 +  V+T  P      PP+F T    +++ E     F C++        +V W   
Sbjct: 141  GDRFSASAVET-RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
              PL   +RV      G  +LEI GV Q D G+YTC   N  G+A++S +L ++G
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score =  102 bits (244), Expect = 4e-20
 Identities = 76/245 (31%), Positives = 112/245 (45%), Gaps = 10/245 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDF 1765
            +T+AP F +P +++ + E   A FE R+   G P+ +V W RNG PI +  R L      
Sbjct: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G  +L +  V+ ED G YTC A N  G    +  L V+   + QL     S  + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS--KTLGDRF 144

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             +S  + R  +       P+F T+L G   + EGQ   + C+I   P P  +V W     
Sbjct: 145  SASAVETRPSIWGEC--PPKFATKL-GRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNV 199

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
             LQ   R   S   G   L+I  V  +D G YTC  +N  G+A  S  L++Q  +S  R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 1946 SQHES 1950
               E+
Sbjct: 260  FVRET 264



 Score =  101 bits (242), Expect = 6e-20
 Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 8/219 (3%)

Query: 4404 PVKPSKP--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            PV PSKP  PIF + +   +V +  Q    V+  G P P + W      I+ S DF    
Sbjct: 545  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 604

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
              T+  L I++VF ED+  +   A N  G  +  A L V+E    G      P F    +
Sbjct: 605  RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP-HDG----TQPWFISKPR 659

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQD 4580
            +V  + GQ V +   + G     V+WL++GK +  D  + ++L+ +  +TL++ +  P  
Sbjct: 660  SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +G+YE +  N  GE  C    ++   + +  P+ +  A+
Sbjct: 720  AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPAS 758



 Score =  100 bits (240), Expect = 1e-19
 Identities = 68/246 (27%), Positives = 114/246 (46%), Gaps = 5/246 (2%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           +   ++ ++ + +      S+     P     PRN  ++EGA A+F+ ++ G P P+VTW
Sbjct: 7   VASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTW 66

Query: 300 FKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-S 357
            +NGQ + +  +  +      T +L +    + D G YT  A N +G    +  L VE S
Sbjct: 67  HRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126

Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
             +   Q   S+ + D       E          P+F        V EG+M RF C++TG
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNE-SGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
           RP P+VTW   +  ++   + ++ V+E +G   L I  V   D GV TC+  N SG+ + 
Sbjct: 187 RPQPQVTWLKGNVPLQP--SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244

Query: 477 QCRLNV 482
              L++
Sbjct: 245 SAELSI 250



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 19/225 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P+F L  +N+ +  G   + + +V G     V W +NG+ +    R  +     GT++L+
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP---------------QTK 4617
            I   + +D GKY C A N +G  +   E  V     K   +P               +T+
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4618 AA---NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             +     PP+    L   +V EGQ   FSCKI G+P P V W KG+  ++PS    +S  
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
                 L I     +D G Y C+  N +G+ +++A+L +   D A+
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 18/246 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-VKTINDFGFVI 3616
            P F   P +L + E ++A FE R+    +   +V W  NG+P+ +G R +      G   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V++ D G YTC+ATN  G   V+ +L V+G        QL     S T   +   
Sbjct: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSA 146

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
              +  R  I  E     PP+F  ++   + V EG    F C++   G P  ++ W     
Sbjct: 147  SAVETRPSIWGEC----PPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNV 199

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC----SAKRD 3792
            P    +RV      G   L+I  +   D G YTC   N  G A+ +A+++     SA R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 3793 IVLESQ 3798
             V E++
Sbjct: 260  FVRETK 265



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 72/227 (31%), Positives = 98/227 (43%), Gaps = 26/227 (11%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP  ++ LK+  + EGQ   F  +         ++ W  N +P++      E    G   
Sbjct: 444  APSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---GVAE 498

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696
            L I   LPED GTYTC A NALG+   S    VH KKS     + E  LP        SK
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS---SRKSEYLLPVA-----PSK 550

Query: 1697 YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
                         AP+F   + D++V +        ++   G+P   V WL NG  I+ S
Sbjct: 551  -----------PTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 597

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
                        +L ++ V PED+GTYTC A N  GE  T + L VQ
Sbjct: 598  EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 59/203 (29%), Positives = 85/203 (41%), Gaps = 18/203 (8%)

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           +AP F  V +D  V EG+     C V G P P +TW +N + I+  Y       E+G   
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTC--EAGVAE 498

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE--------------QVVAPKFVE 495
           L I +    D G  TC+A N  G+ +    + V EK+              +  AP F++
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
             S L V +G  V +  +  G P P + W  +G  I  + +      G   +L I     
Sbjct: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618

Query: 556 SDAAWYQCTAQNVAGSTATRARL 578
            D   Y C A N AG   T+A L
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 16/225 (7%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGFIALDIDYIYA 3762
            N+ + EG    F+ RV   G P  ++ W  NG+P  +G R +      G  +L I  ++ 
Sbjct: 41   NLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS-DAPK 3821
             D G+YTC ATN  G+   T ++T           QL Q +  + + +    R S  A +
Sbjct: 99   EDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGD----RFSASAVE 150

Query: 3822 EEPIV--STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              P +    PPKF T++    V+E +  RF C++  +  P  ++ W +    L    R  
Sbjct: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVS 208

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
                 G   L+I  V  +D G Y C  VN  G+    A +S + L
Sbjct: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 18/242 (7%)

Query: 2899 RRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS 2958
            R  S+P TE   P +I+P      + EG     EG+V  +  P+ ++ W+ NG+ +  G 
Sbjct: 23   RVDSMPLTE--APAFILP-PRNLCIKEGATAKFEGRV--RGYPEPQVTWHRNGQPITSGG 77

Query: 2959 RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK 3017
            RF L     G  +L +  V+E D G YTC+A N  G      TV  T + +  ++   P 
Sbjct: 78   RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPV 135

Query: 3018 GTEGLEKIQNLEDSLRKEPGQQPDDDTGR-PPEFTTVFKDIVDISEGQIAHYEASLIPTG 3076
             ++       L D       +      G  PP+F T    +V + EGQ+  +   +  TG
Sbjct: 136  VSK------TLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKI--TG 186

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
                 + W      ++ S R+      GM VLEI G    D G Y+C   N  G+A +S 
Sbjct: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246

Query: 3137 KL 3138
            +L
Sbjct: 247  EL 248



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 70/260 (26%), Positives = 115/260 (44%), Gaps = 36/260 (13%)

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            EKR + +G    P+F    Q+V+V  G+ + L  +V+   P  + W  NGK ++   +  
Sbjct: 1019 EKRSESQG--TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFI 1075

Query: 4562 ILEEDGTYTLLILE-AYPQDSGKYECVAINSAGEARCDAECVV-SLPATKDKPKPQTK-- 4617
            IL ++G+   + +E A P+D G Y+CVA N AG+A C  +  V   PA+++   P+ K  
Sbjct: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135

Query: 4618 ----------------------AANAPP------EIIEPLKDKIVAEGQAIEFSCKIVGK 4649
                                  A   PP      +II+  +D+ V  G+++E   K+ G 
Sbjct: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
               T  W K  K I+ S++ ++  + +   L I  A  E  G Y  +  N  G       
Sbjct: 1196 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1255

Query: 4710 LKVT-QPDQADNLPALTPLR 4728
            L V  +PD     P  + +R
Sbjct: 1256 LTVVDKPDPPAGTPCASDIR 1275



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 62/249 (24%), Positives = 111/249 (44%), Gaps = 12/249 (4%)

Query: 617 HVERARPYIPPGEEDRV--YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLK 674
           H+ +    + P   D +     P FI+P +++   EG    FE R+   G P  ++ W +
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHR 68

Query: 675 NGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
           NGQ I +  RF       G  SL + +++ +D G+YTC A + +G  +    + +T   +
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV--TVELTVEGS 126

Query: 734 IERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQ 793
             +    P   + +      S  + + SI  +    P+F   L  +  ++EG+   F  +
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECP--PKFATKLGRV-VVKEGQMGRFSCK 183

Query: 794 LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           +T    P  +V W K   P+  S+R++     G   L I  +  +D G YT   VN  G+
Sbjct: 184 IT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241

Query: 854 AISTASIRV 862
           A  +A + +
Sbjct: 242 ASMSAELSI 250



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 65/228 (28%), Positives = 99/228 (43%), Gaps = 14/228 (6%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            +T  P F+  P+++  + EG    FE ++    +   +V W +NGQP+T G RF      
Sbjct: 29   LTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGI 85

Query: 1500 -GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI-QV 1557
             G  +L I  +  ED G YTC A N  G  +V+  LT         S   + G   + + 
Sbjct: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG------SFAKQLGQPVVSKT 139

Query: 1558 LEDRSKYHRTDMVDEVTTQAPI-CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            L DR      +    +  + P    T L  V +KEGQ   F  ++        +V W   
Sbjct: 140  LGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            N PL+  +R + +   G   L+I     +D G YTC  +N  G+A  S
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 77/273 (28%), Positives = 118/273 (43%), Gaps = 33/273 (12%)

Query: 1671 SKKSIYLESQHEGALPRLN---QLEDTSKYQRHSAQDE---VITQAPVFTMPMKDIRVAE 1724
            + + I +E Q + A P+     Q ++  + Q    + E   V+  AP F+  +KD  V E
Sbjct: 399  ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIE 458

Query: 1725 NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYT 1784
             Q   F  +    G P  R+ WL NG PI+ + R T   + G   L+++   PED GTYT
Sbjct: 459  GQ--DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAELHIQDALPEDHGTYT 513

Query: 1785 CRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAP 1844
            C A N LG+   S+ + V  K S                   S + +    V  +   AP
Sbjct: 514  CLAENALGQVSCSAWVTVHEKKS-------------------SRKSEYLLPVAPSKPTAP 554

Query: 1845 RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAAL 1904
             F+  L+   K+ +G       ++   P P   V W  NG  +Q    +         +L
Sbjct: 555  IFLQGLSD-LKVMDGSQVTMTVQVSGNPPPE--VIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 1905 DILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             I  V+ ED+G YTC+A N+ G+  +   L VQ
Sbjct: 612  CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 15/244 (6%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF- 964
            T+ P F  P ++ + IKEG  A FE R+   G    +V W ++G+P+ +  R        
Sbjct: 30   TEAPAFILPPRN-LCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
            G  +L I +V   D G YTC A N  G    +  LT+  +     +   P   + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRF 144

Query: 1025 DASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEWYFN 1082
             AS  +  T   +     P+F   L G   + EGQ   F  ++   PQ  +T    W   
Sbjct: 145  SAS--AVETRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVT----WLKG 197

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
               +  + R+      G   L+I  V  +D GVYT +  N +G+A +SA ++++   S +
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257

Query: 1143 TSSI 1146
             S +
Sbjct: 258  RSFV 261



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 39/107 (36%), Positives = 57/107 (53%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            E +   +  + P F K  +D +V EG   RFDC++ G P PEV WF +D+ IR+  + +I
Sbjct: 1729 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1788

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
              +E GN +L+I++V   D    TC A N  GE      L V   E+
Sbjct: 1789 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1835



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 11/215 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGI 2714
            EG     E +V    +P  ++ W +NG  +T+G R        G  +L I+++  +D G 
Sbjct: 46   EGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2715 YTCKATNLLGEAVSTASIKIEDRHWL-LGESLHPDSL-DRIGALXXXXXXXXXXXXXXXX 2772
            YTC+ATN  G    T  + +E      LG+ +   +L DR  A                 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA----SAVETRPSIWGEC 159

Query: 2773 XXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS 2832
               F + L  +V KEG    F C +     P  ++ W   N PL    R   +       
Sbjct: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQV 217

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            L+I    ++D G+YTC   N  G A+ S  L   G
Sbjct: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 14/252 (5%)

Query: 1970 DDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            D   + E P F  P +N  + EG     E  +    +P  +V W+ NG+P+  G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLD 82

Query: 2030 YDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYL-DTLDEQRLKK 2087
                G  +L I   + ED G Y C+ATN  G    T  + V+      L   +  + L  
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                   E    I  E P   P F T L  +  +KEG    F C++     P +T  W  
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKITGRPQPQVT--WLK 196

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG---- 2203
                ++   R   +   G   L+I     +D G Y C   N  G+A  +  L + G    
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256

Query: 2204 HRNIILDTQHPN 2215
            +R+ + +T+  N
Sbjct: 257  NRSFVRETKATN 268



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 61/225 (27%), Positives = 102/225 (45%), Gaps = 13/225 (5%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P    P F+   R    + EG TA FE +V    +P  ++ ++ NG+ + S  RF +   
Sbjct: 28   PLTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCG 84

Query: 2297 F-GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRE 2355
              G  SL I     ED G+Y+ +A N  G     +++ +T +GS   +  +P   + + +
Sbjct: 85   IRGTFSLVIHAVHEEDRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2356 LESAEPFK-RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
              SA   + RP I        P F   L  +  ++EGQ   F C++   G P  +V W +
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKI--TGRPQPQVTWLK 196

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                ++ S+R++ +   G   + I  V  +D GVY C   N  G+
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 26/240 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++ P F    +   + E   A+FE    G P P + W+R   PI +   F +      + 
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE------------------------E 4502
             L+I  V  ED   +   A N  G  + +  L VE                         
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149

Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
            + R    G  PP F      V V  GQ+ R   K+TG     V WLK    +QP  R  +
Sbjct: 150  ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE-CVVSLPATKDKPKPQTKAANA 4621
             E++G   L I      D G Y C+ +N +G+A   AE  +  L +       +TKA N+
Sbjct: 210  SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 10/224 (4%)

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
            + + D  C      T D  K ++++    P   + L+D  VAEG+ +   C++   P  T
Sbjct: 1001 DVKNDVNCKRGHAGTTDNEK-RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1059

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W    K +K +K+  +S+     ++ I +A PED G YKCVA N AG+   + ++ V 
Sbjct: 1060 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD 1119

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQ--ITSKIKPTIQWLREGALIPET---PDFQ 4768
                ++N  A   ++        P    T+   T K KP  +   + A+ P+    P+ Q
Sbjct: 1120 DAPASENTKA-PEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1178

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  G  +V L G      T   TC       Q++ S  + V++
Sbjct: 1179 KVRAG-ESVELFGKV--TGTQPITCTWMKFRKQIQESEHMKVEN 1219



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 1/98 (1%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLR 4681
            P   + ++D  V EG A  F CKI G P P V W+K D+ I+ S++FQ+    D   +L 
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
            IS+   +D+  Y C A NS G  T  A+L V   ++ +
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1837



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 66/240 (27%), Positives = 97/240 (40%), Gaps = 28/240 (11%)

Query: 1303 EDITVMQ-APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
            E + VM+ AP FS  L +   +EG +  L+C ++  G    R+ W  NG+PI+     R 
Sbjct: 436  EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RS 490

Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
              E     L +    PED G YTC A N LG+   S  + V  KK             K 
Sbjct: 491  TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKS 540

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
            +YL   +  K T          P F+     ++ V++G  V    ++    +   +V W 
Sbjct: 541  EYLLPVAPSKPT---------APIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWL 588

Query: 1482 KNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541
             NG  +     F         +L I ++  ED+G YTC A N  G       LT +   D
Sbjct: 589  HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 71/270 (26%), Positives = 105/270 (38%), Gaps = 23/270 (8%)

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G V  VA +   +T+     + ++   +  AP F+     L ++EG       R  G P 
Sbjct: 2   GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 520 PRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P++TW ++G PI       +     G  +L I      D   Y C A N +G     AR 
Sbjct: 62  PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG-----ARQ 116

Query: 579 YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQ 638
                       K+L  P  +K                 VE  RP I  GE      PP+
Sbjct: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSASA-------VE-TRPSI-WGE-----CPPK 162

Query: 639 FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDM 698
           F   L  V   EG    F  +I   G P  ++ WLK    ++ S+R +   + G   L++
Sbjct: 163 FATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220

Query: 699 LSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +N  D G YTC  V+ +G A   A L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 1/93 (1%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYT 4570
            V P F+ T +++ V  G   R D K+ G    +V W K+ + ++     +I  +EDG  +
Sbjct: 1738 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1797

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            L+I +    D  KY C A+NS GEA C AE +V
Sbjct: 1798 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 64/250 (25%), Positives = 102/250 (40%), Gaps = 11/250 (4%)

Query: 3125 ATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKI 3183
            A++   +  +SV    VD     + P F    +N+  +K+G +A FE  V    +P  ++
Sbjct: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QV 64

Query: 3184 EWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             W+ NGQP+    R        G   L I      D G+Y C A N  G    + T+   
Sbjct: 65   TWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELT 122

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +G    +  QP     + +  S    + + PS     PPKF T++  V  + EGQ   F
Sbjct: 123  VEGSFAKQLGQPVVSKTLGDRFSASAVETR-PSIWGECPPKFATKLGRVV-VKEGQMGRF 180

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
              ++     P  +V W      L    R       G+ +L+I    +++ G Y C+  N 
Sbjct: 181  SCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238

Query: 3363 LGRDSTKANL 3372
             G+ S  A L
Sbjct: 239  SGKASMSAEL 248



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
            +K++  ED S+       E   +  P F   +    ++ EG +A ++C+IE YPDP   V
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPE--V 1771

Query: 1879 EWYFNGKVLQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             W+ + + ++    ++   D  G  +L I  V G+D  +YTCKA+N+LG+A  +  L V+
Sbjct: 1772 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831

Query: 1938 SKE 1940
            + E
Sbjct: 1832 TME 1834



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 64/248 (25%), Positives = 99/248 (39%), Gaps = 10/248 (4%)

Query: 1303 EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPA 1362
            + + + +AP F     N+   EG     E R++  G    +V W  NG+PI +G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLD 82

Query: 1363 YEF-DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
                   +L + +V+ ED G YTC+ATN  G       + +  +     +   P   + +
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPVVSKTL 140

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
                  S  +    I       P+F T+   +  V EGQ   F CK+        +V W 
Sbjct: 141  GDRFSASAVETRPSIWGECP--PKFATKLGRVV-VKEGQMGRFSCKITGRPQP--QVTWL 195

Query: 1482 KNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541
            K   P+    R       G   L+I  +  +D G+YTC  VN  G   +S  L+ +    
Sbjct: 196  KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255

Query: 1542 IVRSTQNE 1549
              RS   E
Sbjct: 256  ANRSFVRE 263



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 68/272 (25%), Positives = 110/272 (40%), Gaps = 33/272 (12%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDIID------ESVTIKPRFVTRPKSIENVI 1457
            A + + +E Q  S   K +    +   K+   +         + + P F +  K    VI
Sbjct: 399  ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA-VI 457

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EGQ    +C +        ++ W  NGQP+      R   + G   L I D + ED G Y
Sbjct: 458  EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512

Query: 1518 TCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
            TC A N +G  +VSC  +   T    +S++             +S+Y       + T  A
Sbjct: 513  TCLAENALG--QVSC--SAWVTVHEKKSSR-------------KSEYLLPVAPSKPT--A 553

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            PI    L ++++ +G +     ++    +   +V W HN   ++    F         +L
Sbjct: 554  PIFLQGLSDLKVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
             I    PED+GTYTC A N+ GE  T  +  V
Sbjct: 612  CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/243 (23%), Positives = 99/243 (40%), Gaps = 35/243 (14%)

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-- 425
           S +I+ T       R++      AP F+   ++  + EG   +F+ RV G P P+VTW  
Sbjct: 9   SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68

Query: 426 ----------FINDRQIRDDYN---HKILVNESGNHALMITN--------VTLSDSG--- 461
                     F+ D  IR  ++   H +   + G +    TN        V L+  G   
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128

Query: 462 ------VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
                 VV+    ++   +A + R ++  +     PKF  +   + V+EG+    + +  
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGE---CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           G P P++TW K  VP+ P+  + +    G   L+I      D   Y C   N +G  +  
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245

Query: 576 ARL 578
           A L
Sbjct: 246 AEL 248



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 59/227 (25%), Positives = 90/227 (39%), Gaps = 10/227 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+ P  N   + EG     E R+   G P  +V W  NG+ +T G RF          
Sbjct: 33   PAFILPPRNLC-IKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 1237 LDIIHAT-SADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
              +IHA    D G+YT  A N  G+   + +   +E S      Q  Q +    L +  +
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVT-VELTVEGSFA---KQLGQPVVSKTLGDRFS 145

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                + R  I     P+F+  L  +   EG      C++   G    +V W     P++ 
Sbjct: 146  ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQP 203

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
              R   + +     L++  V  +D GVYTC   N  G+A  S  L +
Sbjct: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/217 (26%), Positives = 91/217 (41%), Gaps = 14/217 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGL 2580
            EG  A +E RV   G P  +  W+ NG  +  G RF       G  +L I++V   D G 
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2581 YMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQI--QLKEAAMNKVPEMFVDTGV 2638
            Y C+A N +G                  Q  +P   + +  +   +A+   P ++ +   
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFA--KQLGQPVVSKTLGDRFSASAVETRPSIWGEC-- 159

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
               P F T L     + EGQ      ++  R  P  ++ W K  V L   AR+  +   G
Sbjct: 160  --PPKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNG 214

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            +  L I+ +  DD G+YTC   N  G+A  +A + I+
Sbjct: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 6/119 (5%)

Query: 1415 PSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            P   EK++  ED S+     + +E   +KP F    + +E V+EG    F+CK+E   D 
Sbjct: 1711 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1769

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
              +V WFK+ Q +     F+  +D  G  +L I D+  +D   YTC+AVN +G  E +C
Sbjct: 1770 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATC 1824



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 6/103 (5%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            + EE+P  +P F   +  LE + EG  A F+C++E   DP +   WF + Q IR    ++
Sbjct: 1731 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQ 1787

Query: 2160 TTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              +D  G  +L I     +D   Y CKA N LGEA  TCT ++
Sbjct: 1788 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCTAEL 1828



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 62/234 (26%), Positives = 99/234 (42%), Gaps = 14/234 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            FI    N+  KEG    FE  V    +P  ++ W  N +P+ SG R+          SL 
Sbjct: 35   FILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I   +EED G YTC+ATN  G+   +  L   G     F  Q  Q        ++   + 
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSAS- 147

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
             A   RPS+   E P P++   +     + EGQ+     ++  +  P  ++ W      L
Sbjct: 148  -AVETRPSIWG-ECP-PKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPL 201

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            +  +R  ++   G   L++  V + D G+YTC   N  G+A  S+ +     D+
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 67/267 (25%), Positives = 104/267 (38%), Gaps = 22/267 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F++V KD   I EGQ    + S+   G     I W  NG+ I+ +   R+    G+  
Sbjct: 445  PSFSSVLKDCAVI-EGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQ-----------KPRFTTHIQ 3156
            L I      D GTY+C A N  GQ   S  +   +K   +           KP     +Q
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             +  LK    +    TV    +P  ++ W HNG  ++ S             L I     
Sbjct: 559  GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618

Query: 3217 HDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPST 3276
             D+G Y C A+N  GE  T+A +          +  QP  ++K R + +  G        
Sbjct: 619  EDTGTYTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWFISKPRSVTASLGQSVLISCA 674

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFE 3303
             + +P   +  ++D   L +  + HFE
Sbjct: 675  IAGDPFPTVHWLRDGKALCK-DTGHFE 700



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 53/219 (24%), Positives = 93/219 (42%), Gaps = 30/219 (13%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLR 4681
            P  I P ++  + EG   +F  ++ G P P V W++ G  +    ++         ++L 
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4682 ISEAFPEDEGDYKCVAYNSAG--RVTVAAKLK------VTQPDQADNL------------ 4721
            I     ED G Y C A N +G  +VTV   ++      + QP  +  L            
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4722 PAL---------TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
            P++         T L  +VV EGQ  +F  +IT + +P + WL+    +  +    +  +
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                VL I    ++D G +TC     +G+   SA+L ++
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 59/227 (25%), Positives = 96/227 (42%), Gaps = 27/227 (11%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++ AP F++ LK    ++EGQ   L+  V  R  P  +I W  NG  +      +ST + 
Sbjct: 441  MEVAPSFSSVLKDC-AVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 494

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI-EDRHWLLGESLHPDSLDRIGAL 2756
            G+  L I     +D G YTC A N LG+   +A + + E +     E L P +  +  A 
Sbjct: 495  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA- 553

Query: 2757 XXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL 2816
                              +F+  L+++   +G  +     V+ S +P  ++ W  N   +
Sbjct: 554  -----------------PIFLQGLSDLKVMDGSQV--TMTVQVSGNPPPEVIWLHNGNEI 594

Query: 2817 PSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +      +  SL I   + ED+G YTC+A NS G   T   L
Sbjct: 595  QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 62/232 (26%), Positives = 94/232 (40%), Gaps = 28/232 (12%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   LK    ++EGQ   F  +   +      + W  NG+ I  A   ++  + G   
Sbjct: 445  PSFSSVLKDC-AVIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I     ED G YT +A NA G+   SA +TV  + S                  +S++
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----------------RKSEY 542

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            + P   +     + P+F+Q LS+   V +G  + +  ++   G+P   V W HNG  +  
Sbjct: 543  LLP---VAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQE 596

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
               F         +L I      DTG YT  A N  G   T A++ V E  D
Sbjct: 597  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 5/143 (3%)

Query: 2319 AINALGHCTS-AISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
            A+ A+G  +S A+   ++ + S       P   EK+   E         + E     +P 
Sbjct: 1682 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1741

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSM 2436
            F++ +++++ + EG  A FDC++    DP  +V WF++++ I +S      +D  G  S+
Sbjct: 1742 FSKTIRDLE-VVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSL 1798

Query: 2437 TISHVRDEDEGVYMCRASNLLGE 2459
             IS V  +D+  Y C+A N LGE
Sbjct: 1799 IISDVCGDDDAKYTCKAVNSLGE 1821



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 54/227 (23%), Positives = 89/227 (39%), Gaps = 11/227 (4%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            + EG+ L L+ QV   +DP   I W  NGK L+      L+ +    ++ +      D G
Sbjct: 1040 VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097

Query: 2983 IYTCKAYNKRGEAFTSSTVYC----TSKDNLIERTQHPKGTEGLEKIQNLED--SLRKEP 3036
            +Y C A N  G+A  S  V       S++      +  +    L  +   E   +++K+P
Sbjct: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
              +       PP+    F +   +  G+       +  TG Q +   W    K I+ S  
Sbjct: 1158 APKTPPKAAMPPQIIQ-FPEDQKVRAGESVELFGKV--TGTQPITCTWMKFRKQIQESEH 1214

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            ++   +     L IL  +    G Y+    NK G  +  V L  VDK
Sbjct: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 44/140 (31%), Positives = 66/140 (47%), Gaps = 5/140 (3%)

Query: 4374 GDKEITRKITSTETTE-IEHKAQTQERVVEGPV--KPSKPPIFTKKMQPCRVFEHEQARF 4430
            G K  T   TS    E +E +    +  +E     KP   P F+K ++   V E   ARF
Sbjct: 1700 GRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARF 1759

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489
            + + +G P P + W++++  I+ S  FQI +       LII  V  +D A +   A N  
Sbjct: 1760 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1819

Query: 4490 GTAKCSANLVVEEKRRQGRG 4509
            G A C+A L+V E   +G G
Sbjct: 1820 GEATCTAELIV-ETMEEGEG 1838



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 67/228 (29%), Positives = 98/228 (42%), Gaps = 28/228 (12%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F + +KD  ++ EG    F  +    G    R+ WL +G+P++ + R T     G   
Sbjct: 445  PSFSSVLKD-CAVIEG--QDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAE 498

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I+     D G YTC A NA+GQ + SA +T+  KK             K +YL   + 
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKSEYLLPVAP 548

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
             SK T         P FL  L    K+++G       +V    +    V W  NG +I  
Sbjct: 549  -SKPT--------APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 596

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            +            +L I  V  ED+G YT  A N+AGE +  A +TV+
Sbjct: 597  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/155 (30%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 710  TCRAVSATGVAETKAVLH-VTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ 768
            T  AV A G   + A++  ++ R +   +   P   + ++  ED S+   +   EE+   
Sbjct: 1679 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1738

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827
            +P F + ++DL E+ EG  A F+ ++    DP   V W+KD + I  S      ++  G 
Sbjct: 1739 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             SL I  +  +D   YT +AVN LGEA  TA + V
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 46/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 983  TCRAYNAIGQATTSANLTIVT-KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            T  A  AIG+ ++ A ++ ++ +K        P   EK++  ED S+       E K   
Sbjct: 1679 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1738

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGY 1100
            KP F   ++   ++VEG +A F+ ++E   D    V W+ + + I  +   Q  Y + G 
Sbjct: 1739 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPD--PEVVWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             +L I+ V  +D   YT  A N+ GEA  +A + VET
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1832



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F +  ++    +G  A+F+ K+ G P P V W +    + E   + + Y+E  G+ SL
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1798

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            +I  +   D+ +YTC A N  GEA C+
Sbjct: 1799 IISDVCGDDDAKYTCKAVNSLGEATCT 1825



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 20/239 (8%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P FI   ++  ++E    +FE RV    +P  ++ W+RNG+ + SG R+     + G  S
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  V+ ED G+Y C A N  G    + T+      ++ ++    + + +      +  
Sbjct: 91   LVIHAVHEEDRGKYTCEATN--GSGARQVTV------ELTVEGSFAKQLGQPVVSKTLG- 141

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
               ++++    T   ++    + PP+F T++  +  + E +  +F C++   G P  +V 
Sbjct: 142  --DRFSASAVETRPSIWG---ECPPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVT 193

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W     PL    R +     G   +    V  +D G Y C   N  G     A +   G
Sbjct: 194  WLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 12/238 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F   ++D+ VAE +    + ++    DP   + W  NG  ++ +  +    +    +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-------QSKASLQLESQHESALQKIQ 1822
            ++++   PED G Y C A N+ G+A  S  + V        +KA      + +S+L  + 
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 1823 QLEDSSRYQRREDVEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
              E  +  +++   +     A P  I Q     K+  G+S     ++     P +   W 
Sbjct: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG-TQP-ITCTWM 1203

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
               K +Q     +  N    + L IL    E  G YT    N LG   + + L V  K
Sbjct: 1204 KFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 3/130 (2%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +L   ED S+    +  +E     P F+  ++D+ V E  AA F+ ++    DP+  V W
Sbjct: 1716 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1773

Query: 1747 LRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             ++   I  S      +D  G  +L +  V  +D   YTC+A+N LGEA  ++ L V++ 
Sbjct: 1774 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1833

Query: 1806 ASLQLESQHE 1815
               + E + E
Sbjct: 1834 EEGEGEGEEE 1843



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 38/120 (31%), Positives = 62/120 (51%), Gaps = 5/120 (4%)

Query: 1953 EKIQYLEDDSR-YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
            EK++  ED S+ +  AV ++   V KP F K I++ EV EG     +  +    DP   V
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHV-KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EV 1771

Query: 2012 EWYCNGRPVQQGHRFKTTYDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             W+ + + +++   F+  YD  G  +L I     +D   Y CKA N++GEA  T+ + V+
Sbjct: 1772 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 61/212 (28%), Positives = 85/212 (40%), Gaps = 26/212 (12%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG     +C V     P +T  W  NGQ I+     R+T + G   L I     ED GTY
Sbjct: 458  EGQDFVLQCSVRGTPVPRIT--WLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPP 2242
             C A N LG+   +C+  V  H             +  R+ E       + V   K + P
Sbjct: 513  TCLAENALGQV--SCSAWVTVHEK-----------KSSRKSEYL-----LPVAPSKPTAP 554

Query: 2243 RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
             F+  L     V +G       QV    +P   + + HNG  +Q +  FH        SL
Sbjct: 555  IFLQGL-SDLKVMDGSQVTMTVQVSG--NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             IQ   PED G Y+ +A N+ G   +   +TV
Sbjct: 612  CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 55/235 (23%), Positives = 92/235 (39%), Gaps = 14/235 (5%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F + L ++   EG  + L+C++    D    + W  NGK +KT      + E    +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV------IAKKDLILESQHP-SGLEKIQ 1422
            + +    PED G+Y C A N  G+A  SC + V         K   ++S+ P S L  + 
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 1423 YLEDTSRYKKTDI--IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEW 1480
              E  +  KK           + P+ +  P+  + V  G+ V    K+       +   W
Sbjct: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKV--TGTQPITCTW 1202

Query: 1481 FKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             K  + +      +  +      L I+    E  G YT    N +G+ +    LT
Sbjct: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1257



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 8/123 (6%)

Query: 43  HFTRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPV 102
           H ++   +   S  D  P+T   P    PP      +N    +G  AKFEG++RG P P 
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEA-PAFILPP------RNLCIKEGATAKFEGRVRGYPEPQ 63

Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           V+W R   P+    ++ +    + G  SL+I  +   D G+YTC A N  G    +V + 
Sbjct: 64  VTWHRNGQPITSGGRFLLDCGIR-GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122

Query: 163 PEG 165
            EG
Sbjct: 123 VEG 125



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 63/218 (28%), Positives = 91/218 (41%), Gaps = 28/218 (12%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F + L+    V EG+    +C V     P  RI +  NG+ +Q A     T + G   
Sbjct: 445  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYARS---TCEAGVAE 498

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L IQ  +PED G Y+  A NALG  + +  +TV  K S    S++ E             
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSE------------- 541

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            +  P  P   T   P+F Q L ++  + +G       ++   G+P  +V W  N   I++
Sbjct: 542  YLLPVAPSKPT--APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 596

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S            S+ I  V  ED G Y C A N  GE
Sbjct: 597  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 58/243 (23%), Positives = 97/243 (39%), Gaps = 17/243 (6%)

Query: 258  RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            RS    + P   QK ++  + EG     Q Q+S +P   + W  NG+ L  + K  I++ 
Sbjct: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1079

Query: 318  HNHT-TLRVRNTQKSDSGHYTLLAENPNG-----CIVTSGYLAVESPTESYVQDQRSQYI 371
                 ++ +      D G Y  +A+N  G     C VT         T++     R    
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1139

Query: 372  TDTQQRETEERIEISEK---------ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            +      TE    + +K         A+ PQ ++  +D+ V  G+      +VTG     
Sbjct: 1140 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1199

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             TW    +QI++  + K+  +E+G+  L I        G  T +  NK G    Q  L V
Sbjct: 1200 CTWMKFRKQIQESEHMKVENSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258

Query: 483  IEK 485
            ++K
Sbjct: 1259 VDK 1261



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 35/237 (14%)

Query: 3558 PEFTTTPSDLILSENSSAHFEC--RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            P F++   D  + E      +C  R  PV     R+ W  NG+P+      ++  + G  
Sbjct: 445  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVP----RITWLLNGQPI---QYARSTCEAGVA 497

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I      D G YTC A N  G+  VSC   V              H K  +   + L
Sbjct: 498  ELHIQDALPEDHGTYTCLAENALGQ--VSCSAWVT------------VHEKKSSRKSEYL 543

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
                     + +   KP  P F   + D + V +G  V    +V   G+P   + W HNG
Sbjct: 544  ---------LPVAPSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 591

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
                     H        +L I  ++  D G YTC A N  G   T A +T     D
Sbjct: 592  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 4/154 (2%)

Query: 1251 TVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            T  AV  +G   + A++  +  R        +    E+++  ED ++   +   +     
Sbjct: 1679 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1738

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD-YV 1368
             P FS+ + ++E VEG+    +C+++   D    V WF + + I+    F+  Y+ D   
Sbjct: 1739 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNC 1796

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L +  V  +D   YTC+A N LGEA  +  L V
Sbjct: 1797 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 51/226 (22%), Positives = 93/226 (41%), Gaps = 31/226 (13%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F S L +    EG +   +C+V  +  P  +I W  N +P+      +ST +     L I
Sbjct: 447  FSSVLKDCAVIEGQDFVLQCSVRGT--PVPRITWLLNGQPIQYA---RSTCEAGVAELHI 501

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                 ED G YTC A N+ G  + S  +                       V + + +R 
Sbjct: 502  QDALPEDHGTYTCLAENALGQVSCSAWV----------------------TVHEKKSSRK 539

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLE 2955
            ++   P  P    P     +   ++ ++++G  + +  QV    +P  ++ W  NG  ++
Sbjct: 540  SEYLLPVAPSK--PTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQ 595

Query: 2956 QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            +   F         +L + +V+  D+G YTC+A+N  GE  T + +
Sbjct: 596  ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 60/244 (24%), Positives = 100/244 (40%), Gaps = 16/244 (6%)

Query: 2226 QGHSTRIEVE---EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
            +GH+   + E   E + + P F  +L+   HV EGK    +CQV    DP   I +  NG
Sbjct: 1010 RGHAGTTDNEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSS--DPPATIIWTLNG 1066

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV----TAKG 2338
            K L++     ++ +    S+ I+  +PED G Y   A N  G    +  +TV     ++ 
Sbjct: 1067 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1126

Query: 2339 SIISE--SQRPE-GLEKIRELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTA 2394
            +   E  S+RP+  L  +   ES    K+   P+ P     P           ++ G++ 
Sbjct: 1127 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1186

Query: 2395 HFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
                ++   G   +   W +  K I++S  +   +      +TI   R E  G Y     
Sbjct: 1187 ELFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1244

Query: 2455 NLLG 2458
            N LG
Sbjct: 1245 NKLG 1248



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 3/134 (2%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + +  + +G+     + E   S+    PPK A K     ++EG   +F  +++G P+P+V
Sbjct: 133 QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-- 355
           TW K    L  S +  +   +    L +    + D G YT L  N +G    S  L++  
Sbjct: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252

Query: 356 -ESPTESYVQDQRS 368
            +S   S+V++ ++
Sbjct: 253 LDSANRSFVRETKA 266



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 61/232 (26%), Positives = 91/232 (39%), Gaps = 28/232 (12%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F+  +KD   V EG      C V   G P  RI W  NG+P        +  + G   
Sbjct: 445  PSFSSVLKD-CAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPI---QYARSTCEAGVAE 498

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L I      D G YTC A N  G  + +A +T   K+            S  K + L   
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK------------SSRKSEYL--- 543

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
             +  AP +     T P F+  +    ++  +G +    V+   +P   + W  NG  +  
Sbjct: 544  -LPVAPSK----PTAPIFLQGLSD--LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
               +         SL I  V+ ED+G Y C A N  GE  T+A ++ ++  D
Sbjct: 597  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 4/100 (4%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GY 966
            KP F   I+D + + EG  A F+ ++E   D    V W KD + +  S      ++  G 
Sbjct: 1739 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
             +L I  V   D   YTC+A N++G+AT +A L + T ++
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1835



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 55/224 (24%), Positives = 87/224 (38%), Gaps = 12/224 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG  +  +C V  S DP   I W  N K L +      + + S  S+ I
Sbjct: 1031 FKQKLQDVHVAEGKKLLLQCQV--SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQ-----GKAGLEAVEQA 2890
                 ED G+Y C A N  G A  S  +    D     +T+ P+      K+ L  V   
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQV-TVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147

Query: 2891 E-EARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949
            E +A + K   P  P      P+ II    + ++  G+ + L G+V       +   W  
Sbjct: 1148 ESDATVKKKPAPKTPPKAAMPPQ-IIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMK 1204

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
              K +++    K+ +      L ++   +   G YT    NK G
Sbjct: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 4/124 (3%)

Query: 2613 PESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            P + E+++ +E       E   +      P F+  ++  + +VEG     + ++E   DP
Sbjct: 1711 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1769

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
              ++ WFK+  ++      +  +D  G  +L I+ +  DD   YTCKA N LGEA  TA 
Sbjct: 1770 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1827

Query: 2732 IKIE 2735
            + +E
Sbjct: 1828 LIVE 1831



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 5/101 (4%)

Query: 3687 IEDEKPN-PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
            + +EKP+  P F+  I+D ++V EG    FDC++E   DP   + WF + +         
Sbjct: 1731 VAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQ 1787

Query: 3746 -TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               ++ G  +L I  +   D  +YTC+A N  G AT TA++
Sbjct: 1788 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1828



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 4/120 (3%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            EKL++ ED      +   EE+    P F+  + ++E + EG  A F+ ++    DP  +V
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV-EGSAARFDCKIEGYPDP--EV 1771

Query: 3455 EWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             W+ + +S++    F+  + + G   L IS    +D  +Y C+A N+ GEA  TA + V+
Sbjct: 1772 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 55/226 (24%), Positives = 90/226 (39%), Gaps = 14/226 (6%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F  +L     ++EG+    +C++    DP   + W  NGK L++      S +    
Sbjct: 1028 APAFKQKLQD-VHVAEGKKLLLQCQVSS--DPPATIIWTLNGKTLKTTKFIILSQEGSLC 1084

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-------QSKESIIRDSQHESALEKI 1955
            ++ I     ED G Y C A N+ GQA  S ++ V        +K   ++  + +S+L  +
Sbjct: 1085 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144

Query: 1956 QYLEDDSRYKR--AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW 2013
               E D+  K+  A +        PQ  +  ++ +V  G  V L   +T     T    W
Sbjct: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT--CTW 1202

Query: 2014 YCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
                + +Q+    K         L IL A  E  G Y     N +G
Sbjct: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 1/87 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYE 4785
            +RD+ V EG  A+F  +I     P + W ++   I E+  FQ+ + E  N  L+I +   
Sbjct: 1746 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1805

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +D   +TC+A  + G+   +A+L+V++
Sbjct: 1806 DDDAKYTCKAVNSLGEATCTAELIVET 1832



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 52/251 (20%), Positives = 93/251 (37%), Gaps = 10/251 (3%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E   E     P F + LQD+  + EG+    + Q++  SDP   + W  +G+ +  +  I
Sbjct: 1019 EKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFI 1075

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV----AARSTVTADLGIP 875
                     S++I     ED G Y   A N  G+A  +  + V    A+ +T   ++   
Sbjct: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935
              +  +                     P++   P+     +DQ  ++ G       ++  
Sbjct: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ-KVRAGESVELFGKVT- 1193

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             G   +   W+K  + ++ S  +    +     LTI +      G YT    N +G    
Sbjct: 1194 -GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQA 1252

Query: 996  SANLTIVTKKD 1006
              NLT+V K D
Sbjct: 1253 QVNLTVVDKPD 1263



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 5/108 (4%)

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            E  +++ +  +    +E+P V   P F   I+   V E    RF+C++E   DP+  + W
Sbjct: 1718 ESEEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1773

Query: 3866 YRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            +++ + +     ++  YD  G  SL I  V  +D  +Y C+AVN  GE
Sbjct: 1774 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1821



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 58/258 (22%), Positives = 90/258 (34%), Gaps = 10/258 (3%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G++GT D        G  P F     D+ ++E      +C++   +D    + W  NGK 
Sbjct: 1011 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKT 1068

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI--IL 3657
            L T   +    +     + I      D GLY C A N  G+A  SC++ V          
Sbjct: 1069 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1128

Query: 3658 EPQLPSHF-KSGTESIQKLEE--TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVH 3714
             P++ S   KS    +   E   T+ K+       +   PP+  ++  ++  V  G  V 
Sbjct: 1129 APEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI-IQFPEDQKVRAGESVE 1187

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
               +V   G   +   W    +       +   N      L I        G YT    N
Sbjct: 1188 LFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVEN 1245

Query: 3775 KWGSATTTAKITCSAKRD 3792
            K GS      +T   K D
Sbjct: 1246 KLGSRQAQVNLTVVDKPD 1263



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 39/109 (35%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 470 KSGETA-FQCR-LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
           K  +T  F+C  L V+E    VAP F        V EG+  VL     GTP PRITW  +
Sbjct: 426 KENQTVKFRCEGLAVME----VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 481

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           G PI      R   + G + L I  A   D   Y C A+N  G  +  A
Sbjct: 482 GQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 527



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 32/232 (13%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F + ++D   ++EGQ    +  +     P  ++ W  NG+ + +    R+  + G+  
Sbjct: 445  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401
            L I     E+ G Y C+A N LG+ S  A +    K++      L               
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL--------------- 543

Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461
                      V   K  AP+F   LS+++ + +G       +++    P  +V W  NG 
Sbjct: 544  --------LPVAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVSGNPPP--EVIWLHNGN 592

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             ++    F          L I   +PED+G Y C A+N+ GE  T A + VQ
Sbjct: 593  EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + E+R E   +  AP F +  QD  V EGK     C+V+  P   + W +N + ++    
Sbjct: 1017 DNEKRSE--SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-K 1073

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE---KEQVVAPKFV 494
              IL  E    ++ I      D G+  CVA+N +G+    C++ V +    E   AP+  
Sbjct: 1074 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1133

Query: 495  ER 496
             R
Sbjct: 1134 SR 1135



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 57/243 (23%), Positives = 98/243 (40%), Gaps = 19/243 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L+  + + EG+    + +V   SD   T+ W  NGK + +   I    +    +
Sbjct: 1029 PAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            + I     ED G+Y  VA+N AG+A+ S  +TV+   + + +   +    K+R  + S  
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT---KAPEMKSRRPKSS-- 1140

Query: 1163 VEPMYQIEEIS--KSKPVFVQP--LSNPPPV---SEGKNIHLECRLEPMGDPT----MRV 1211
            + P+   E  +  K KP    P   + PP +    E + +     +E  G  T    +  
Sbjct: 1141 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1200

Query: 1212 EWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             W    + +      K         L I+ A     G YT+   N LGS      + V++
Sbjct: 1201 TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260

Query: 1272 RSD 1274
            + D
Sbjct: 1261 KPD 1263



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 7/137 (5%)

Query: 2201 VAGHRNIILDTQHPNGLEKIRQLE--AQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            ++G ++       P   EK+   E  +Q     +  E+P + P  + ++      V EG 
Sbjct: 1698 LSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP--YFSKTIRDLEVVEGS 1755

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSV 2317
             A F+C++E   DP   + ++ + ++++ +  F I +D  G  SL I     +D  +Y+ 
Sbjct: 1756 AARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1813

Query: 2318 KAINALGHCTSAISMTV 2334
            KA+N+LG  T    + V
Sbjct: 1814 KAVNSLGEATCTAELIV 1830



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 3/131 (2%)

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
            E+++  ED S+     + +E     P  + +++++E+ EG  A F+ ++    D   +V 
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVV 1772

Query: 1613 WYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
            W+ +++ ++    F  + +  G  +L I     +D   YTC+A+N+LGEA  +   IV +
Sbjct: 1773 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1832

Query: 1672 KKSIYLESQHE 1682
             +    E + E
Sbjct: 1833 MEEGEGEGEEE 1843



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           P +P+ PIF Q   + +   G       ++ GNP P V W      + E   +   + ++
Sbjct: 548 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQR 605

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
               SL I+++ P D G YTC A N  GE
Sbjct: 606 GTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 57/243 (23%), Positives = 89/243 (36%), Gaps = 36/243 (14%)

Query: 3031 SLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090
            SL  +P +         P F    +++  I EG  A +E  +   G     + W  NG+ 
Sbjct: 16   SLSVDPSRVDSMPLTEAPAFILPPRNLC-IKEGATAKFEGRV--RGYPEPQVTWHRNGQP 72

Query: 3091 IEASHRIRTVYAF-GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC--------- 3140
            I +  R        G   L I      D G Y+C ATN  G  +++V+L           
Sbjct: 73   ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLG 132

Query: 3141 ---VDKSKGQK-----------------PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
               V K+ G +                 P+F T +  +  +K+GQ   F C +     P 
Sbjct: 133  QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKIT--GRPQ 189

Query: 3181 MKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             ++ W     P++ S R+      G  VL+I      D G Y C   N  G+    A ++
Sbjct: 190  PQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELS 249

Query: 3241 CYG 3243
              G
Sbjct: 250  IQG 252



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/231 (24%), Positives = 89/231 (38%), Gaps = 28/231 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P F+ VL   + + EGQ    +  V   G P  R  W +NG  ++     R+T + G   
Sbjct: 445  PSFSSVLKDCAVI-EGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L I   +  D G Y C A N  G                        +W  +  K+++  
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCS-------------------AWVTVHEKKSSRK 539

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                + V      APIF   L    K+++G  V +  QV     P  ++ W  NG  +  
Sbjct: 540  SEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQVTMTVQVSGNPPP--EVIWLHNGNEIQE 596

Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
                         +L I  +  +D+G YTC+A N  GE  + A + +++ H
Sbjct: 597  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 647



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 52/242 (21%), Positives = 89/242 (36%), Gaps = 12/242 (4%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            E +G AP F   L ++ ++ EG+    + +++   DP   + W  NGK+LK  ++F    
Sbjct: 1023 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT-TKFIILS 1078

Query: 3474 DFGFVI-LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ---GKRNIILESQLPKGME 3529
              G +  + I    PED G Y C A N+ G+A  +  + V       N        +  +
Sbjct: 1079 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1138

Query: 3530 GTIDKIAALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
             ++  +   E  +       P+   ++  PP+    P D  +    S     ++      
Sbjct: 1139 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQ 1196

Query: 3588 SMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
             +   W    K +     +K  N      L I    Q   G YT    N+ G       L
Sbjct: 1197 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256

Query: 3648 QV 3649
             V
Sbjct: 1257 TV 1258



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F+  L  +  M+G ++    ++   G+P  ++ WL NG  I+ S  F    R    SL
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +  +  +D+G YTC A ++ G   T+AVL V
Sbjct: 612 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIK 4749
            GD K VA +   + +++              PA + P R++ + EG  A+F+ ++    +
Sbjct: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            P + W R G  I     F ++  G      L+I   +EED G +TC AT  +G  + + +
Sbjct: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 4808 LVVK 4811
            L V+
Sbjct: 121  LTVE 124



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 57/237 (24%), Positives = 91/237 (38%), Gaps = 33/237 (13%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F   L+D   + EG++  F  Q +    P  R+ W  +G+PI  +    S    G   
Sbjct: 445  PSFSSVLKDCAVI-EGQD--FVLQCSVRGTPVPRITWLLNGQPIQYAR---STCEAGVAE 498

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L+I     ED G+YT  A N LG+   +A + V  + +         +  Y+        
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-------SRKSEYLLPVA---- 547

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                         P     P F   + D + + +G       ++   G+    V WL +G
Sbjct: 548  -------------PSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 591

Query: 950  RPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
              ++ S            +L I+ V   D G YTC A+N+ G+  T A LT+    D
Sbjct: 592  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 5/90 (5%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F  + K+    +G +   +  +RG P P ++W     P+    +Y+ R   + G   L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYA-RSTCEAGVAEL 499

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            I+   P D G YTC A N  G+  CS ++
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWV 529



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 630  EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            E++ +  P F   ++ +  +EG    F+ +IE   DP  ++ W K+ QSI  S  F   +
Sbjct: 1733 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDY 1790

Query: 690  -RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
               G  SL +  +   D  +YTC+AV++ G A   A L V
Sbjct: 1791 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 27/226 (11%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F   LK    +EG     +  +   G P  +I WL NGQ I+ +    S    G   L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 499

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
            +     +D G YTC A +A G     A + V  + +  +                 S+Y
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK-----------------SEY 542

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
               +  + T+  P F++ L DL ++ +G       Q++   +P   V W  +G  I  S
Sbjct: 543 LLPVAPSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 597

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                       SL I  +  ED G+YT  A N  GE  + A + V
Sbjct: 598 EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 55/225 (24%), Positives = 97/225 (43%), Gaps = 29/225 (12%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            P F++ +++   + +GQ    +C+V     P  +I W  NGQP++++   ++  + G   
Sbjct: 445  PSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQG 3268
            L I      D G Y C A N  G+    A +  + K      S + + L  +        
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSEYLLPV-------- 546

Query: 3269 AQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG 3328
                 PS P+A  P F+  + D+ K+++G       ++    +P  +V W +NG ++   
Sbjct: 547  ----APSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 597

Query: 3329 HRYRTFHDFGIV-ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              +  F   G    L I   + E++G Y C A N  G   T+A L
Sbjct: 598  EDFH-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 19/282 (6%)

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQ 1979
            + +  +G A     L   SKE + +D +++   ++      D+  +   Q  +     P 
Sbjct: 976  ETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTA-----PA 1030

Query: 1980 FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDI 2039
            F + +++  V EG  + L+  ++  +DP   + W  NG+ ++       + +    ++ I
Sbjct: 1031 FKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088

Query: 2040 LYAYAEDTGTYMCKATNAVGEAVTTSSVKVD---AKSGLYLDTLDEQRLKKI------QE 2090
              A  ED G Y C A N  G+A  +  V VD   A        +  +R K         E
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148

Query: 2091 LEKYERPKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
             +   + KP  +  P    P  +      + ++ G+      +V       +T  W    
Sbjct: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMKFR 1206

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            ++I+     +  +      L IL    E  G Y     NKLG
Sbjct: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F   L+    + EG+ + L+ QV   +DP   I W  NG TL T   +  + +  L 
Sbjct: 1028 APAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1084

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            ++SI     +D G+Y C A N  G+A  +  + ++D
Sbjct: 1085 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1120



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 11/154 (7%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT-TDSGTYSCRATNKWGQAEISVK-LEC 3140
            +W   G  + A  R+ ++     ++  + G K+ T S T    A     + ++S   LE 
Sbjct: 1675 KWQKTGNAVRAIGRLSSM----AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1730

Query: 3141 VDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199
            V + K   KP F+  I+++E + +G +A F+C +    DP+  + W+ + Q +R S   +
Sbjct: 1731 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQ 1787

Query: 3200 -TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                + G   L I+     D  +Y C+A N  GE
Sbjct: 1788 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1821



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP F+  L +   + EG++   +  +  T  P  ++ W  NG+ ++     R+ C+ G  
Sbjct: 444  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 497

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQL----PKGMEGTI-- 3532
             L I    PED G Y C A N  G+   +A + V  K++      L    P      I  
Sbjct: 498  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 557

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECR 3580
              ++ L+   G+  T+T +     PPE     +   + E+   HFE R
Sbjct: 558  QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 16/245 (6%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            +S+G  P F   +Q++  + +G+    +C V    DP   I W  NG+ ++ +  I    
Sbjct: 1023 ESQGTAPAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1079

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATIN----CYGKGGVYLESLQP-D 3255
            +     + I      D G Y C A N  G  E   + T++            ++S +P  
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1139

Query: 3256 SLAKIRELESLQGAQQQ-TPSTP--SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDP 3312
            SL  +   ES    +++  P TP  +A PP+ I Q  +  K+  G+S     ++      
Sbjct: 1140 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQII-QFPEDQKVRAGESVELFGKVTGTQ-- 1196

Query: 3313 DLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +   W    K++      +  +      L IL   +E+ G Y  +  NKLG    + NL
Sbjct: 1197 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256

Query: 3373 KCTSK 3377
                K
Sbjct: 1257 TVVDK 1261



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 42/151 (27%), Positives = 69/151 (45%), Gaps = 9/151 (5%)

Query: 1127 AQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNP 1186
            A +S     ++ +   TS ++    E    + ++ F+E +   EE    KP F + + + 
Sbjct: 1693 AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQA-FLEAV--AEEKPHVKPYFSKTIRDL 1749

Query: 1187 PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFVALDIIHATSA 1245
              V EG     +C++E   DP   V WF + +S+     F+  YD  G  +L I      
Sbjct: 1750 EVV-EGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1806

Query: 1246 DTGEYTVRAVNHLGSAHTSA--IVRVIERSD 1274
            D  +YT +AVN LG A  +A  IV  +E  +
Sbjct: 1807 DDAKYTCKAVNSLGEATCTAELIVETMEEGE 1837



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 4078 PKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGH 4137
            P    + EK+   E   Q   E V EE K    P F      + V EG  ARF C++ G+
Sbjct: 1708 PTSPLNAEKLESEEDVSQAFLEAVAEE-KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1766

Query: 4138 PKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P P V+W  +  +I     +++ YD
Sbjct: 1767 PDPEVVWFKDDQSIRESRHFQIDYD 1791



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT--YDGMYHFD 4168
            P F+  P  + ++EG  A+F  RV G+P+P+V W  NG  I +G R+ L     G +   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4169 IPKTRQYDTGK 4179
            I    + D GK
Sbjct: 93   IHAVHEEDRGK 103



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 37/239 (15%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            ++   P F + +K   V E +    +C V  +  P  RI W  NG+ +      R+  + 
Sbjct: 440  VMEVAPSFSSVLKDCAVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 494

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            G   L I     ED G Y C A N  G+      +SC     +       +  ++SE L 
Sbjct: 495  GVAELHIQDALPEDHGTYTCLAENALGQ------VSCSAWVTV----HEKKSSRKSEYL- 543

Query: 3945 QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPN 4004
             +     K T+ ++L                    Q  + L  M+ ++    +   G+P 
Sbjct: 544  -LPVAPSKPTAPIFL--------------------QGLSDLKVMDGSQVTMTVQVSGNPP 582

Query: 4005 MKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
             +V W  NG  +     F         ++    V+PED+G Y C A N  G   T+AV+
Sbjct: 583  PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 40/129 (31%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 44  FTRQMTTQVESS--GDRQPITA--GRP---GEPSPPIFEQIFKNARFAQGGNAKFEGKLR 96
           F +Q+   V S   GDR   +A   RP   GE  PP F          +G   +F  K+ 
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE-CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P V+W +   PL    + S+  +E+ G   L I  +   D G YTC   N  G+A 
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSV--SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243

Query: 157 CSVYIQPEG 165
            S  +  +G
Sbjct: 244 MSAELSIQG 252



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 54/241 (22%), Positives = 84/241 (34%), Gaps = 15/241 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  +++D + V EG  +   C+V    DP   I W  NG+   T   +    +    +
Sbjct: 1029 PAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER- 3813
            + I+     D G Y C A N  G A  + ++T          ++ P+  S      L   
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD-DAPASENTKAPEMKSRRPKSSLPPV 1144

Query: 3814 -GRISDA-------PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
             G  SDA       PK  P  + PP+ I   +   V   E V    +V   +   +   W
Sbjct: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQ--PITCTW 1202

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             +  K +      +         L IL    E  G Y     N  G    +  ++    P
Sbjct: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262

Query: 3926 D 3926
            D
Sbjct: 1263 D 1263



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD-FSYVSLD 2834
            F   + ++   EG    F+C +E   DP  ++ WF +++ +     ++  +D     SL 
Sbjct: 1742 FSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I+    +D   YTCKA NS G AT +  L
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1828



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/86 (25%), Positives = 41/86 (47%)

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            + Q  AP F ++   ++V EG+ ++L  +    P   I W  +G  +     + +  +G 
Sbjct: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1082

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
              ++ I +A   D   Y+C A+N AG
Sbjct: 1083 LCSVSIEKALPEDRGLYKCVAKNDAG 1108



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592
            +K+ + E  S        E +    P F+ T  DL + E S+A F+C++    D    V 
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VV 1772

Query: 3593 WFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            WF + + +      +   ++ G   L I  V   D   YTCKA N  GEAT + +L V+
Sbjct: 1773 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 56/240 (23%), Positives = 92/240 (38%), Gaps = 17/240 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP     L++V + EG++   + ++   SD    + W  N K LK+      +      +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV------HSKKSIYLESQH-EGALPRLN 1689
            + I   LPED G Y C A N  G+A  S    V       + K+  ++S+  + +LP + 
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ--AAHFEARLI--PVGDPKLRVE 1745
              E  +  ++  A        P   MP + I+  E+Q   A     L     G   +   
Sbjct: 1146 GTESDATVKKKPAP----KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W++    I+ S  +   +      L +     E  G YT    N+LG       L V  K
Sbjct: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            E  G  P F   L  + ++ EG +   +C+V   +DP  TI W  NG+ ++       + 
Sbjct: 1023 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1079

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +    ++ I     ED G Y C A N  G+A  +C + V
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 1/100 (1%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNH 320
            P   P  ++  R+ ++ EG+ A+F  ++ G P P V WFK+ Q +  S   +I      +
Sbjct: 1736 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             +L + +    D   YT  A N  G    +  L VE+  E
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1835



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 2/111 (1%)

Query: 470  KSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            +S E   Q  L  + +E+  V P F +    L V EG     + +  G P P + W KD 
Sbjct: 1718 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1777

Query: 529  VPIIPNPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              I  +   +I + + G  +L I      D A Y C A N  G     A L
Sbjct: 1778 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1828



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++ ++ EG+     C++    DP   + W  N K ++ +  I  + +    S
Sbjct: 1029 PAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            ++I     ED G+Y C A N  G+
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQ 1109



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNKYS 119
           +T   P + + P F    ++   + G +      + G+P P V W R  KA   +   + 
Sbjct: 641 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 700

Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSV 159
           +  NE     +L++K++ P   G+Y    +N+ GE  C V
Sbjct: 701 VLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQV 738



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 43/192 (22%), Positives = 68/192 (35%), Gaps = 10/192 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            T+++     +   P F  ++Q    + E +    +CQ++   DP   + W  NGK L   
Sbjct: 1016 TDNEKRSESQGTAPAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTT 1072

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV------Y 4073
                   +    +++     PED G Y C A N  G  E    +     P          
Sbjct: 1073 KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEM 1132

Query: 4074 DSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCR 4133
             S+ PK         E +A+ +  P       KA  PP  +  P+   V  GE      +
Sbjct: 1133 KSRRPKSSLPPVLGTESDATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVRAGESVELFGK 1191

Query: 4134 VTGHPKPRVMWL 4145
            VTG       W+
Sbjct: 1192 VTGTQPITCTWM 1203



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+Q  ++   A+G     + ++  +P   + WT     L +  K+ +  +++    S+
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFII-LSQEGSLCSV 1086

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             I++  P D G Y C A+N  G+A CS  +
Sbjct: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQV 1116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERD 2980
            ++VEG     + ++E   DP+  + W+ + + + +   F++  D  G  +L + DV   D
Sbjct: 1750 EVVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1807

Query: 2981 SGIYTCKAYNKRGEA 2995
               YTCKA N  GEA
Sbjct: 1808 DAKYTCKAVNSLGEA 1822



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            +D  K      T P F  +++   V E + +  +C+V    DP   I W  NGK L +  
Sbjct: 1016 TDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTK 1073

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
                  +    S+ I     ED G Y C A ND G+
Sbjct: 1074 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1109



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/92 (22%), Positives = 41/92 (44%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F +K+Q   V E ++   + +   +P   I W      +K +    +    +   + I
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
             +   ED  ++  VA+N  G A+CS  + V++
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1120



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 3013 TQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASL 3072
            T  P      EK+++ ED  +       ++     P F+   +D+ ++ EG  A ++  +
Sbjct: 1705 TGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKI 1763

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
                D  +V  WF + ++I  S   +  Y   G   L I      D   Y+C+A N  G+
Sbjct: 1764 EGYPDPEVV--WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1821

Query: 3132 AEISVKL--ECVDKSKGQ 3147
            A  + +L  E +++ +G+
Sbjct: 1822 ATCTAELIVETMEEGEGE 1839



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 14/127 (11%)

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPK----FITQIQDVTKLVEGQSAHFEARLVPV 3309
            P S     +LES +   Q      + E P     F   I+D+ ++VEG +A F+ ++   
Sbjct: 1708 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGY 1766

Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHD----FGIVILDILYCYEENSGEYECVATNKLGR 3365
             DP+  V WF + + +     ++  +D      ++I D+  C ++++ +Y C A N LG 
Sbjct: 1767 PDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV--CGDDDA-KYTCKAVNSLGE 1821

Query: 3366 DSTKANL 3372
             +  A L
Sbjct: 1822 ATCTAEL 1828



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GF 2565
            KP F++ +    E+ EG  A ++ ++    DP +   W+ +   ++    F+  +D  G 
Sbjct: 1739 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEV--VWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I+ V  +D   Y CKA+N  G
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLG 1820



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 2232 IEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL-QSAA 2289
            + V+EP   + P F+++ R  T    G++    C +    DP   + +  +GKAL +   
Sbjct: 641  LTVQEPHDGTQPWFISKPRSVTASL-GQSVLISCAI--AGDPFPTVHWLRDGKALCKDTG 697

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS-MTVTAKGSIISESQRPE 2348
             F +  +    +L ++   P  AG+Y +   N +G C+  +S M   +    +   + P 
Sbjct: 698  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 757

Query: 2349 GLEKI 2353
              E +
Sbjct: 758  SCEDL 762



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 13/120 (10%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL--PSGHRYR 3879
            +EP   T P FI++ +S T    + V   C +    DP   + W R+GK L   +GH + 
Sbjct: 644  QEPHDGTQPWFISKPRSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGH-FE 700

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
             + +    +L +  V    +G+Y     N  GE        C     ++LQN   R + R
Sbjct: 701  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--------CSCQVSLMLQNSSARALPR 752



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 33/88 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P+ ++      VR GE V L  +  GT     TW K    I  +  +++      S L I
Sbjct: 1169 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1228

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A+      Y    +N  GS   +  L
Sbjct: 1229 LAARQEHCGCYTLLVENKLGSRQAQVNL 1256



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 1738 GDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            GDP   V WLR+G  + + +     + +     L +K V P  +G Y     N +GE   
Sbjct: 677  GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 736

Query: 1797 SSTLFVQSKASLQLESQHESA 1817
              +L +Q+ ++  L    E A
Sbjct: 737  QVSLMLQNSSARALPRGREPA 757



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
            +E+RSE    +   P F Q L     + EG+    + +V    DP     W +NG  LK 
Sbjct: 1018 NEKRSES---QGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT 1071

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                  + +    ++ I   +  D GLY C A N AG
Sbjct: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAG 1108


>AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kinase
            isoform 3B protein.
          Length = 1793

 Score =  175 bits (427), Expect = 2e-42
 Identities = 185/750 (24%), Positives = 299/750 (39%), Gaps = 58/750 (7%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGE 4045
            E  T KFE ++   G P  +V W  NG+P+    RF       G  ++    V+ ED G+
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 4046 YLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEES 4105
            Y C ATN  G  +    +   G     +  QL + + S        AS   T   +  E 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE- 158

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGM 4164
               CPP F +    V V+EG+  RF C++TG P+P+V WL     +   +R  ++  +GM
Sbjct: 159  ---CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGM 215

Query: 4165 YHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQY 4224
               +I    Q D G    +             L +       +G L +A R +  ET   
Sbjct: 216  QVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI-------QG-LDSANRSFVRET--- 264

Query: 4225 QRTETELEKTFEERQVLQRQGVIDH-RPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE 4283
            + T +++ K  E   V+ ++  +D      K K    P+             +     +E
Sbjct: 265  KATNSDVRK--EVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ---PPRE 319

Query: 4284 LENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQ 4343
             + E      R    T         +T    A+   +     L       E+R +    +
Sbjct: 320  SKLESCKDSPRTAPQTPVLQKTSSSITLQA-ARVQPEPRAPGLGVLSPSGEERKRPAPPR 378

Query: 4344 KPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEG 4403
                P           V  A  ++   E   D    +  +  ++ E++   QT +   EG
Sbjct: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKEN-QTVKFRCEG 437

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
                   P F+  ++ C V E +    +    G P+P I W     PI+ +   +    +
Sbjct: 438  LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEA 494

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG-IVP--------P 4514
              + L I+    ED   +  +AEN  G   CSA + V EK+   +   ++P        P
Sbjct: 495  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLI 4573
             F     ++ V  G  V +  +V+G  P +V WL NG ++Q +  +   E+ GT ++L I
Sbjct: 555  IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLWI 613

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
             E +P+D+G Y C A NSAGE R  A   V       +P   T+     P  I   +   
Sbjct: 614  QEVFPEDTGTYTCEAWNSAGEVRTQAVLTV------QEPHDGTQ-----PWFISKPRSVT 662

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             + GQ++  SC I G P PTV W + G  L K + +F++ +  D +TL + +  P   G 
Sbjct: 663  ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
            Y+ +  N  G  +    L + Q   A  LP
Sbjct: 723  YEILLKNRVGECSCQVSL-MLQNSSARALP 751



 Score =  142 bits (345), Expect = 2e-32
 Identities = 163/650 (25%), Positives = 263/650 (40%), Gaps = 59/650 (9%)

Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFG 1633
            T+AP      +N+ IKEG  A FE R+    +   +V W+ N +P+ SG RF  +    G
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 1634 FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLED 1693
              +L I +   ED G YTC A N  G    +    V    +  L  Q   +    ++   
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQL-GQPVVSKTLGDRFSA 146

Query: 1694 TSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753
            ++   R S   E     P F   +  + V E Q   F  ++   G P+ +V WL+  VP+
Sbjct: 147  SAVETRPSIWGEC---PPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPL 201

Query: 1754 EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ----SKASLQ 1809
            + S R++     G   L +  VN +D G YTC  +N  G+A  S+ L +Q    +  S  
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261

Query: 1810 LESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNG-PTKLSEGQ------SA 1862
             E++  ++  + +     S+  + + +E A         Q  G P   +  Q      S 
Sbjct: 262  RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321

Query: 1863 HYECRIEPYPDPNMRVEWYFNGKV-LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
               C+  P   P   V    +  + LQ+    R   +     L +L+  GE+        
Sbjct: 322  LESCKDSPRTAPQTPVLQKTSSSITLQAA---RVQPEPRAPGLGVLSPSGEERKRPAPPR 378

Query: 1922 INNLGQAVSSI-RLNVQSKES---IIRDSQHESALEKI------QYLEDDSRYKRAVQDD 1971
                      +   +V SK +   I  + Q +SA  K       Q ++++   K   +  
Sbjct: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGL 438

Query: 1972 SFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031
            + +   P F   +K+  V EG    L+ ++     P  R+ W  NG+P+Q     ++T +
Sbjct: 439  AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCE 493

Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQEL 2091
             G   L I  A  ED GTY C A NA+G+   ++ V V  K                +  
Sbjct: 494  AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK----------------KSS 537

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
             K E   P+   +P   P+FL  L+   +LK  D +     V+   +P   + W HNG +
Sbjct: 538  RKSEYLLPVAPSKP-TAPIFLQGLS---DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593

Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            I+    +         +L I   + ED+GTY C+A N  GE      L V
Sbjct: 594  IQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score =  131 bits (317), Expect = 5e-29
 Identities = 86/307 (28%), Positives = 135/307 (43%), Gaps = 7/307 (2%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V PSF+   ++  V  GQ   L   V GT    + WL NG+ +Q   R+    E G   L
Sbjct: 443  VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTC--EAGVAEL 499

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK---PQTKAANAPPEIIEP 4628
             I +A P+D G Y C+A N+ G+  C A   V    +  K +   P   +    P  ++ 
Sbjct: 500  HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L D  V +G  +  + ++ G P P V W      I+ S+ F   +   +++L I E FPE
Sbjct: 560  LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPE 619

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            D G Y C A+NSAG V   A L V +P        ++  R +    GQ       I    
Sbjct: 620  DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 679

Query: 4749 KPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             PT+ WLR+G AL  +T  F+++   +   L++        G +        G+      
Sbjct: 680  FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739

Query: 4808 LVVKSKT 4814
            L++++ +
Sbjct: 740  LMLQNSS 746



 Score =  109 bits (261), Expect = 3e-22
 Identities = 78/314 (24%), Positives = 129/314 (41%), Gaps = 19/314 (6%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P  +   ++  + EG D   Q  + G P PR+TW  NGQ +  +             L +
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHI 501

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
           ++    D G YT LAEN  G +  S ++ V     S    ++S+Y+              
Sbjct: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----RKSEYLLPVAP--------- 548

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
             K  AP F++   D  V +G       +V+G P PEV W  N  +I++  +        
Sbjct: 549 -SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRG 606

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
             H+L I  V   D+G  TC A N +GE   Q  L V E      P F+ +  ++    G
Sbjct: 607 TQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLG 666

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           + V+++    G P P + W +DG  +  +     +  +    TL + + +   A  Y+  
Sbjct: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 726

Query: 565 AQNVAGSTATRARL 578
            +N  G  + +  L
Sbjct: 727 LKNRVGECSCQVSL 740



 Score =  107 bits (258), Expect = 7e-22
 Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 14/235 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-G 3476
            +AP F +P  N+  ++EG  A FE R+    +P  +V W+ NG+ + +G RF   C   G
Sbjct: 31   EAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 3477 FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIA 3536
               L I   + ED G+Y C A N  G    T  + V+G        QL + +   + K  
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPV---VSKTL 140

Query: 3537 ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
                 +  V+T  P      PP+F T    +++ E     F C++        +V W   
Sbjct: 141  GDRFSASAVET-RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
              PL   +RV      G  +LEI GV Q D G+YTC   N  G+A++S +L ++G
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score =  102 bits (244), Expect = 4e-20
 Identities = 76/245 (31%), Positives = 112/245 (45%), Gaps = 10/245 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDF 1765
            +T+AP F +P +++ + E   A FE R+   G P+ +V W RNG PI +  R L      
Sbjct: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G  +L +  V+ ED G YTC A N  G    +  L V+   + QL     S  + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS--KTLGDRF 144

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             +S  + R  +       P+F T+L G   + EGQ   + C+I   P P  +V W     
Sbjct: 145  SASAVETRPSIWGEC--PPKFATKL-GRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNV 199

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
             LQ   R   S   G   L+I  V  +D G YTC  +N  G+A  S  L++Q  +S  R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 1946 SQHES 1950
               E+
Sbjct: 260  FVRET 264



 Score =  100 bits (240), Expect = 1e-19
 Identities = 68/246 (27%), Positives = 114/246 (46%), Gaps = 5/246 (2%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           +   ++ ++ + +      S+     P     PRN  ++EGA A+F+ ++ G P P+VTW
Sbjct: 7   VASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTW 66

Query: 300 FKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-S 357
            +NGQ + +  +  +      T +L +    + D G YT  A N +G    +  L VE S
Sbjct: 67  HRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126

Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
             +   Q   S+ + D       E          P+F        V EG+M RF C++TG
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNE-SGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
           RP P+VTW   +  ++   + ++ V+E +G   L I  V   D GV TC+  N SG+ + 
Sbjct: 187 RPQPQVTWLKGNVPLQP--SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244

Query: 477 QCRLNV 482
              L++
Sbjct: 245 SAELSI 250



 Score =  100 bits (240), Expect = 1e-19
 Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 8/219 (3%)

Query: 4404 PVKPSKP--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            PV PSKP  PIF + +   +V +  Q    V+  G P P + W      I+ S DF    
Sbjct: 545  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 604

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
              T+  L I++VF ED+  +   A N  G  +  A L V+E    G      P F    +
Sbjct: 605  RGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP-HDG----TQPWFISKPR 659

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQD 4580
            +V  + GQ V +   + G     V+WL++GK +  D  + ++L+ +  +TL++ +  P  
Sbjct: 660  SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +G+YE +  N  GE  C    ++   + +  P+ +  A+
Sbjct: 720  AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPAS 758



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 19/225 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P+F L  +N+ +  G   + + +V G     V W +NG+ +    R  +     GT++L+
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP---------------QTK 4617
            I   + +D GKY C A N +G  +   E  V     K   +P               +T+
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4618 AA---NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             +     PP+    L   +V EGQ   FSCKI G+P P V W KG+  ++PS    +S  
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
                 L I     +D G Y C+  N +G+ +++A+L +   D A+
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 18/246 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-VKTINDFGFVI 3616
            P F   P +L + E ++A FE R+    +   +V W  NG+P+ +G R +      G   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V++ D G YTC+ATN  G   V+ +L V+G        QL     S T   +   
Sbjct: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSA 146

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
              +  R  I  E     PP+F  ++   + V EG    F C++   G P  ++ W     
Sbjct: 147  SAVETRPSIWGEC----PPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNV 199

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC----SAKRD 3792
            P    +RV      G   L+I  +   D G YTC   N  G A+ +A+++     SA R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 3793 IVLESQ 3798
             V E++
Sbjct: 260  FVRETK 265



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 72/227 (31%), Positives = 98/227 (43%), Gaps = 26/227 (11%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP  ++ LK+  + EGQ   F  +         ++ W  N +P++      E    G   
Sbjct: 444  APSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---GVAE 498

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696
            L I   LPED GTYTC A NALG+   S    VH KKS     + E  LP        SK
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS---SRKSEYLLPVA-----PSK 550

Query: 1697 YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
                         AP+F   + D++V +        ++   G+P   V WL NG  I+ S
Sbjct: 551  -----------PTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 597

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
                        +L ++ V PED+GTYTC A N  GE  T + L VQ
Sbjct: 598  EDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 59/203 (29%), Positives = 85/203 (41%), Gaps = 18/203 (8%)

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           +AP F  V +D  V EG+     C V G P P +TW +N + I+  Y       E+G   
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTC--EAGVAE 498

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE--------------QVVAPKFVE 495
           L I +    D G  TC+A N  G+ +    + V EK+              +  AP F++
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
             S L V +G  V +  +  G P P + W  +G  I  + +      G   +L I     
Sbjct: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFP 618

Query: 556 SDAAWYQCTAQNVAGSTATRARL 578
            D   Y C A N AG   T+A L
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 16/225 (7%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGFIALDIDYIYA 3762
            N+ + EG    F+ RV   G P  ++ W  NG+P  +G R +      G  +L I  ++ 
Sbjct: 41   NLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS-DAPK 3821
             D G+YTC ATN  G+   T ++T           QL Q +  + + +    R S  A +
Sbjct: 99   EDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGD----RFSASAVE 150

Query: 3822 EEPIV--STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              P +    PPKF T++    V+E +  RF C++  +  P  ++ W +    L    R  
Sbjct: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVS 208

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
                 G   L+I  V  +D G Y C  VN  G+    A +S + L
Sbjct: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 18/242 (7%)

Query: 2899 RRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS 2958
            R  S+P TE   P +I+P      + EG     EG+V  +  P+ ++ W+ NG+ +  G 
Sbjct: 23   RVDSMPLTE--APAFILP-PRNLCIKEGATAKFEGRV--RGYPEPQVTWHRNGQPITSGG 77

Query: 2959 RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK 3017
            RF L     G  +L +  V+E D G YTC+A N  G      TV  T + +  ++   P 
Sbjct: 78   RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPV 135

Query: 3018 GTEGLEKIQNLEDSLRKEPGQQPDDDTGR-PPEFTTVFKDIVDISEGQIAHYEASLIPTG 3076
             ++       L D       +      G  PP+F T    +V + EGQ+  +   +  TG
Sbjct: 136  VSK------TLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKI--TG 186

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
                 + W      ++ S R+      GM VLEI G    D G Y+C   N  G+A +S 
Sbjct: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246

Query: 3137 KL 3138
            +L
Sbjct: 247  EL 248



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 62/249 (24%), Positives = 111/249 (44%), Gaps = 12/249 (4%)

Query: 617 HVERARPYIPPGEEDRV--YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLK 674
           H+ +    + P   D +     P FI+P +++   EG    FE R+   G P  ++ W +
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHR 68

Query: 675 NGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
           NGQ I +  RF       G  SL + +++ +D G+YTC A + +G  +    + +T   +
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV--TVELTVEGS 126

Query: 734 IERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQ 793
             +    P   + +      S  + + SI  +    P+F   L  +  ++EG+   F  +
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECP--PKFATKLGRV-VVKEGQMGRFSCK 183

Query: 794 LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           +T    P  +V W K   P+  S+R++     G   L I  +  +D G YT   VN  G+
Sbjct: 184 IT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241

Query: 854 AISTASIRV 862
           A  +A + +
Sbjct: 242 ASMSAELSI 250



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 65/228 (28%), Positives = 99/228 (43%), Gaps = 14/228 (6%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            +T  P F+  P+++  + EG    FE ++    +   +V W +NGQP+T G RF      
Sbjct: 29   LTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGI 85

Query: 1500 -GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI-QV 1557
             G  +L I  +  ED G YTC A N  G  +V+  LT         S   + G   + + 
Sbjct: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG------SFAKQLGQPVVSKT 139

Query: 1558 LEDRSKYHRTDMVDEVTTQAPI-CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            L DR      +    +  + P    T L  V +KEGQ   F  ++        +V W   
Sbjct: 140  LGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            N PL+  +R + +   G   L+I     +D G YTC  +N  G+A  S
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 77/273 (28%), Positives = 118/273 (43%), Gaps = 33/273 (12%)

Query: 1671 SKKSIYLESQHEGALPRLN---QLEDTSKYQRHSAQDE---VITQAPVFTMPMKDIRVAE 1724
            + + I +E Q + A P+     Q ++  + Q    + E   V+  AP F+  +KD  V E
Sbjct: 399  ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIE 458

Query: 1725 NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYT 1784
             Q   F  +    G P  R+ WL NG PI+ + R T   + G   L+++   PED GTYT
Sbjct: 459  GQ--DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAELHIQDALPEDHGTYT 513

Query: 1785 CRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAP 1844
            C A N LG+   S+ + V  K S                   S + +    V  +   AP
Sbjct: 514  CLAENALGQVSCSAWVTVHEKKS-------------------SRKSEYLLPVAPSKPTAP 554

Query: 1845 RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAAL 1904
             F+  L+   K+ +G       ++   P P   V W  NG  +Q    +         +L
Sbjct: 555  IFLQGLSD-LKVMDGSQVTMTVQVSGNPPPE--VIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 1905 DILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             I  V+ ED+G YTC+A N+ G+  +   L VQ
Sbjct: 612  WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 15/244 (6%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF- 964
            T+ P F  P ++ + IKEG  A FE R+   G    +V W ++G+P+ +  R        
Sbjct: 30   TEAPAFILPPRN-LCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
            G  +L I +V   D G YTC A N  G    +  LT+  +     +   P   + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRF 144

Query: 1025 DASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEWYFN 1082
             AS  +  T   +     P+F   L G   + EGQ   F  ++   PQ  +T    W   
Sbjct: 145  SAS--AVETRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVT----WLKG 197

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
               +  + R+      G   L+I  V  +D GVYT +  N +G+A +SA ++++   S +
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257

Query: 1143 TSSI 1146
             S +
Sbjct: 258  RSFV 261



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 69/260 (26%), Positives = 114/260 (43%), Gaps = 36/260 (13%)

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            EKR + +G    P+F    Q+V+V  G+ + L  +V+   P  + W  NGK ++   +  
Sbjct: 1019 EKRSESQG--TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFI 1075

Query: 4562 ILEEDGTYTLLILE-AYPQDSGKYECVAINSAGEARCDAECVV-SLPATKDKPKPQTK-- 4617
            IL ++G+   + +E A  +D G Y+CVA N AG+A C  +  V   PA+++   P+ K  
Sbjct: 1076 ILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135

Query: 4618 ----------------------AANAPP------EIIEPLKDKIVAEGQAIEFSCKIVGK 4649
                                  A   PP      +II+  +D+ V  G+++E   K+ G 
Sbjct: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
               T  W K  K I+ S++ ++  + +   L I  A  E  G Y  +  N  G       
Sbjct: 1196 QPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1255

Query: 4710 LKVT-QPDQADNLPALTPLR 4728
            L V  +PD     P  + +R
Sbjct: 1256 LTVVDKPDPPAGTPCASDIR 1275



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 11/215 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGI 2714
            EG     E +V    +P  ++ W +NG  +T+G R        G  +L I+++  +D G 
Sbjct: 46   EGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2715 YTCKATNLLGEAVSTASIKIEDRHWL-LGESLHPDSL-DRIGALXXXXXXXXXXXXXXXX 2772
            YTC+ATN  G    T  + +E      LG+ +   +L DR  A                 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA----SAVETRPSIWGEC 159

Query: 2773 XXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS 2832
               F + L  +V KEG    F C +     P  ++ W   N PL    R   +       
Sbjct: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQV 217

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            L+I    ++D G+YTC   N  G A+ S  L   G
Sbjct: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 36/93 (38%), Positives = 53/93 (56%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            E +   +  + P F K  +D +V EG   RFDC++ G P PEV WF +D+ IR+  + +I
Sbjct: 1677 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1736

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
              +E GN +L+I++V   D    TC A N  GE
Sbjct: 1737 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1769



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 14/252 (5%)

Query: 1970 DDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            D   + E P F  P +N  + EG     E  +    +P  +V W+ NG+P+  G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLD 82

Query: 2030 YDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYL-DTLDEQRLKK 2087
                G  +L I   + ED G Y C+ATN  G    T  + V+      L   +  + L  
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                   E    I  E P   P F T L  +  +KEG    F C++     P +T  W  
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKITGRPQPQVT--WLK 196

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG---- 2203
                ++   R   +   G   L+I     +D G Y C   N  G+A  +  L + G    
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256

Query: 2204 HRNIILDTQHPN 2215
            +R+ + +T+  N
Sbjct: 257  NRSFVRETKATN 268



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 61/225 (27%), Positives = 102/225 (45%), Gaps = 13/225 (5%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P    P F+   R    + EG TA FE +V    +P  ++ ++ NG+ + S  RF +   
Sbjct: 28   PLTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCG 84

Query: 2297 F-GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRE 2355
              G  SL I     ED G+Y+ +A N  G     +++ +T +GS   +  +P   + + +
Sbjct: 85   IRGTFSLVIHAVHEEDRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2356 LESAEPFK-RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
              SA   + RP I        P F   L  +  ++EGQ   F C++   G P  +V W +
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKI--TGRPQPQVTWLK 196

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                ++ S+R++ +   G   + I  V  +D GVY C   N  G+
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 26/240 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++ P F    +   + E   A+FE    G P P + W+R   PI +   F +      + 
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE------------------------E 4502
             L+I  V  ED   +   A N  G  + +  L VE                         
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149

Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
            + R    G  PP F      V V  GQ+ R   K+TG     V WLK    +QP  R  +
Sbjct: 150  ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE-CVVSLPATKDKPKPQTKAANA 4621
             E++G   L I      D G Y C+ +N +G+A   AE  +  L +       +TKA N+
Sbjct: 210  SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 56/224 (25%), Positives = 98/224 (43%), Gaps = 10/224 (4%)

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
            + + D  C      T D  K ++++    P   + L+D  VAEG+ +   C++   P  T
Sbjct: 1001 DVKNDVNCKRGHAGTTDNEK-RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1059

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W    K +K +K+  +S+     ++ I +A  ED G YKCVA N AG+   + ++ V 
Sbjct: 1060 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVD 1119

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQ--ITSKIKPTIQWLREGALIPET---PDFQ 4768
                ++N  A   ++        P    T+   T K KP  +   + A+ P+    P+ Q
Sbjct: 1120 DAPASENTKA-PEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1178

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  G  +V L G      T   TC       Q++ S  + V++
Sbjct: 1179 KVRAG-ESVELFGKV--TGTQPITCTWMKFRKQIQDSEHIKVEN 1219



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 71/270 (26%), Positives = 105/270 (38%), Gaps = 23/270 (8%)

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G V  VA +   +T+     + ++   +  AP F+     L ++EG       R  G P 
Sbjct: 2   GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 520 PRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P++TW ++G PI       +     G  +L I      D   Y C A N +G     AR 
Sbjct: 62  PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG-----ARQ 116

Query: 579 YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQ 638
                       K+L  P  +K                 VE  RP I  GE      PP+
Sbjct: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSASA-------VE-TRPSI-WGE-----CPPK 162

Query: 639 FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDM 698
           F   L  V   EG    F  +I   G P  ++ WLK    ++ S+R +   + G   L++
Sbjct: 163 FATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220

Query: 699 LSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +N  D G YTC  V+ +G A   A L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 66/240 (27%), Positives = 97/240 (40%), Gaps = 28/240 (11%)

Query: 1303 EDITVMQ-APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
            E + VM+ AP FS  L +   +EG +  L+C ++  G    R+ W  NG+PI+     R 
Sbjct: 436  EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RS 490

Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
              E     L +    PED G YTC A N LG+   S  + V  KK             K 
Sbjct: 491  TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKS 540

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
            +YL   +  K T          P F+     ++ V++G  V    ++    +   +V W 
Sbjct: 541  EYLLPVAPSKPT---------APIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWL 588

Query: 1482 KNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541
             NG  +     F         +L I ++  ED+G YTC A N  G       LT +   D
Sbjct: 589  HNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 34/88 (38%), Positives = 48/88 (54%), Gaps = 1/88 (1%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLR 4681
            P   + ++D  V EG A  F CKI G P P V W+K D+ I+ S++FQ+    D   +L 
Sbjct: 1688 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1747

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            IS+   +D+  Y C A NS G  T  A+
Sbjct: 1748 ISDVCGDDDAKYTCKAVNSLGEATCTAE 1775



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 64/250 (25%), Positives = 102/250 (40%), Gaps = 11/250 (4%)

Query: 3125 ATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKI 3183
            A++   +  +SV    VD     + P F    +N+  +K+G +A FE  V    +P  ++
Sbjct: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QV 64

Query: 3184 EWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             W+ NGQP+    R        G   L I      D G+Y C A N  G    + T+   
Sbjct: 65   TWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELT 122

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +G    +  QP     + +  S    + + PS     PPKF T++  V  + EGQ   F
Sbjct: 123  VEGSFAKQLGQPVVSKTLGDRFSASAVETR-PSIWGECPPKFATKLGRVV-VKEGQMGRF 180

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
              ++     P  +V W      L    R       G+ +L+I    +++ G Y C+  N 
Sbjct: 181  SCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238

Query: 3363 LGRDSTKANL 3372
             G+ S  A L
Sbjct: 239  SGKASMSAEL 248



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 1/93 (1%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYT 4570
            V P F+ T +++ V  G   R D K+ G    +V W K+ + ++     +I  +EDG  +
Sbjct: 1686 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1745

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            L+I +    D  KY C A+NS GEA C AE +V
Sbjct: 1746 LIISDVCGDDDAKYTCKAVNSLGEATCTAEHIV 1778



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 64/248 (25%), Positives = 99/248 (39%), Gaps = 10/248 (4%)

Query: 1303 EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPA 1362
            + + + +AP F     N+   EG     E R++  G    +V W  NG+PI +G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLD 82

Query: 1363 YEF-DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
                   +L + +V+ ED G YTC+ATN  G       + +  +     +   P   + +
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPVVSKTL 140

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
                  S  +    I       P+F T+   +  V EGQ   F CK+        +V W 
Sbjct: 141  GDRFSASAVETRPSIWGECP--PKFATKLGRVV-VKEGQMGRFSCKITGRPQP--QVTWL 195

Query: 1482 KNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541
            K   P+    R       G   L+I  +  +D G+YTC  VN  G   +S  L+ +    
Sbjct: 196  KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255

Query: 1542 IVRSTQNE 1549
              RS   E
Sbjct: 256  ANRSFVRE 263



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/243 (23%), Positives = 99/243 (40%), Gaps = 35/243 (14%)

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-- 425
           S +I+ T       R++      AP F+   ++  + EG   +F+ RV G P P+VTW  
Sbjct: 9   SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68

Query: 426 ----------FINDRQIRDDYN---HKILVNESGNHALMITN--------VTLSDSG--- 461
                     F+ D  IR  ++   H +   + G +    TN        V L+  G   
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128

Query: 462 ------VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
                 VV+    ++   +A + R ++  +     PKF  +   + V+EG+    + +  
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGE---CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           G P P++TW K  VP+ P+  + +    G   L+I      D   Y C   N +G  +  
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245

Query: 576 ARL 578
           A L
Sbjct: 246 AEL 248



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 59/227 (25%), Positives = 90/227 (39%), Gaps = 10/227 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+ P  N   + EG     E R+   G P  +V W  NG+ +T G RF          
Sbjct: 33   PAFILPPRNLC-IKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 1237 LDIIHAT-SADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
              +IHA    D G+YT  A N  G+   + +   +E S      Q  Q +    L +  +
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVT-VELTVEGSFA---KQLGQPVVSKTLGDRFS 145

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                + R  I     P+F+  L  +   EG      C++   G    +V W     P++ 
Sbjct: 146  ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQP 203

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
              R   + +     L++  V  +D GVYTC   N  G+A  S  L +
Sbjct: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/217 (26%), Positives = 91/217 (41%), Gaps = 14/217 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGL 2580
            EG  A +E RV   G P  +  W+ NG  +  G RF       G  +L I++V   D G 
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2581 YMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQI--QLKEAAMNKVPEMFVDTGV 2638
            Y C+A N +G                  Q  +P   + +  +   +A+   P ++ +   
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFA--KQLGQPVVSKTLGDRFSASAVETRPSIWGEC-- 159

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
               P F T L     + EGQ      ++  R  P  ++ W K  V L   AR+  +   G
Sbjct: 160  --PPKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNG 214

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            +  L I+ +  DD G+YTC   N  G+A  +A + I+
Sbjct: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 68/272 (25%), Positives = 110/272 (40%), Gaps = 33/272 (12%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDIID------ESVTIKPRFVTRPKSIENVI 1457
            A + + +E Q  S   K +    +   K+   +         + + P F +  K    VI
Sbjct: 399  ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA-VI 457

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EGQ    +C +        ++ W  NGQP+      R   + G   L I D + ED G Y
Sbjct: 458  EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512

Query: 1518 TCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
            TC A N +G  +VSC  +   T    +S++             +S+Y       + T  A
Sbjct: 513  TCLAENALG--QVSC--SAWVTVHEKKSSR-------------KSEYLLPVAPSKPT--A 553

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            PI    L ++++ +G +     ++    +   +V W HN   ++    F         +L
Sbjct: 554  PIFLQGLSDLKVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
             I    PED+GTYTC A N+ GE  T  +  V
Sbjct: 612  WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 6/119 (5%)

Query: 1415 PSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            P   EK++  ED S+     + +E   +KP F    + +E V+EG    F+CK+E   D 
Sbjct: 1659 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1717

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
              +V WFK+ Q +     F+  +D  G  +L I D+  +D   YTC+AVN +G  E +C
Sbjct: 1718 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATC 1772



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 6/100 (6%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            + EE+P  +P F   +  LE + EG  A F+C++E   DP +   WF + Q IR    ++
Sbjct: 1679 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQ 1735

Query: 2160 TTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
              +D  G  +L I     +D   Y CKA N LGEA  TCT
Sbjct: 1736 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCT 1773



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 62/234 (26%), Positives = 99/234 (42%), Gaps = 14/234 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            FI    N+  KEG    FE  V    +P  ++ W  N +P+ SG R+          SL 
Sbjct: 35   FILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I   +EED G YTC+ATN  G+   +  L   G     F  Q  Q        ++   + 
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSAS- 147

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
             A   RPS+   E P P++   +     + EGQ+     ++  +  P  ++ W      L
Sbjct: 148  -AVETRPSIWG-ECP-PKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPL 201

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            +  +R  ++   G   L++  V + D G+YTC   N  G+A  S+ +     D+
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 53/219 (24%), Positives = 93/219 (42%), Gaps = 30/219 (13%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLR 4681
            P  I P ++  + EG   +F  ++ G P P V W++ G  +    ++         ++L 
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4682 ISEAFPEDEGDYKCVAYNSAG--RVTVAAKLK------VTQPDQADNL------------ 4721
            I     ED G Y C A N +G  +VTV   ++      + QP  +  L            
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4722 PAL---------TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
            P++         T L  +VV EGQ  +F  +IT + +P + WL+    +  +    +  +
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                VL I    ++D G +TC     +G+   SA+L ++
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 67/267 (25%), Positives = 104/267 (38%), Gaps = 22/267 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F++V KD   I EGQ    + S+   G     I W  NG+ I+ +   R+    G+  
Sbjct: 445  PSFSSVLKDCAVI-EGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQ-----------KPRFTTHIQ 3156
            L I      D GTY+C A N  GQ   S  +   +K   +           KP     +Q
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             +  LK    +    TV    +P  ++ W HNG  ++ S             L I     
Sbjct: 559  GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFP 618

Query: 3217 HDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPST 3276
             D+G Y C A+N  GE  T+A +          +  QP  ++K R + +  G        
Sbjct: 619  EDTGTYTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWFISKPRSVTASLGQSVLISCA 674

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFE 3303
             + +P   +  ++D   L +  + HFE
Sbjct: 675  IAGDPFPTVHWLRDGKALCK-DTGHFE 700



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 37/123 (30%), Positives = 65/123 (52%), Gaps = 4/123 (3%)

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
            +K++  ED S+       E   +  P F   +    ++ EG +A ++C+IE YPDP   V
Sbjct: 1663 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPE--V 1719

Query: 1879 EWYFNGKVLQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             W+ + + ++    ++   D  G  +L I  V G+D  +YTCKA+N+LG+A  +    V+
Sbjct: 1720 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 1779

Query: 1938 SKE 1940
            + E
Sbjct: 1780 TME 1782



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 59/227 (25%), Positives = 96/227 (42%), Gaps = 27/227 (11%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++ AP F++ LK    ++EGQ   L+  V  R  P  +I W  NG  +      +ST + 
Sbjct: 441  MEVAPSFSSVLKDC-AVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 494

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI-EDRHWLLGESLHPDSLDRIGAL 2756
            G+  L I     +D G YTC A N LG+   +A + + E +     E L P +  +  A 
Sbjct: 495  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA- 553

Query: 2757 XXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL 2816
                              +F+  L+++   +G  +     V+ S +P  ++ W  N   +
Sbjct: 554  -----------------PIFLQGLSDLKVMDGSQV--TMTVQVSGNPPPEVIWLHNGNEI 594

Query: 2817 PSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +      +  SL I   + ED+G YTC+A NS G   T   L
Sbjct: 595  QESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 5/143 (3%)

Query: 2319 AINALGHCTS-AISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
            A+ A+G  +S A+   ++ + S       P   EK+   E         + E     +P 
Sbjct: 1630 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1689

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSM 2436
            F++ +++++ + EG  A FDC++    DP  +V WF++++ I +S      +D  G  S+
Sbjct: 1690 FSKTIRDLE-VVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSL 1746

Query: 2437 TISHVRDEDEGVYMCRASNLLGE 2459
             IS V  +D+  Y C+A N LGE
Sbjct: 1747 IISDVCGDDDAKYTCKAVNSLGE 1769



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 62/232 (26%), Positives = 94/232 (40%), Gaps = 28/232 (12%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   LK    ++EGQ   F  +   +      + W  NG+ I  A   ++  + G   
Sbjct: 445  PSFSSVLKDC-AVIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I     ED G YT +A NA G+   SA +TV  + S                  +S++
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----------------RKSEY 542

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            + P   +     + P+F+Q LS+   V +G  + +  ++   G+P   V W HNG  +  
Sbjct: 543  LLP---VAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQE 596

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
               F         +L I      DTG YT  A N  G   T A++ V E  D
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 55/227 (24%), Positives = 89/227 (39%), Gaps = 11/227 (4%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            + EG+ L L+ QV   +DP   I W  NGK L+      L+ +    ++ +      D G
Sbjct: 1040 VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRG 1097

Query: 2983 IYTCKAYNKRGEAFTSSTVYC----TSKDNLIERTQHPKGTEGLEKIQNLED--SLRKEP 3036
            +Y C A N  G+A  S  V       S++      +  +    L  +   E   +++K+P
Sbjct: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
              +       PP+    F +   +  G+       +  TG Q +   W    K I+ S  
Sbjct: 1158 APKTPPKAAMPPQIIQ-FPEDQKVRAGESVELFGKV--TGTQPITCTWMKFRKQIQDSEH 1214

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            I+   +     L IL  +    G Y+    NK G  +  V L  VDK
Sbjct: 1215 IKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 67/228 (29%), Positives = 98/228 (42%), Gaps = 28/228 (12%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F + +KD  ++ EG    F  +    G    R+ WL +G+P++ + R T     G   
Sbjct: 445  PSFSSVLKD-CAVIEG--QDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAE 498

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I+     D G YTC A NA+GQ + SA +T+  KK             K +YL   + 
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKSEYLLPVAP 548

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
             SK T         P FL  L    K+++G       +V    +    V W  NG +I  
Sbjct: 549  -SKPT--------APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 596

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            +            +L I  V  ED+G YT  A N+AGE +  A +TV+
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F +  ++    +G  A+F+ K+ G P P V W +    + E   + + Y+E  G+ SL
Sbjct: 1688 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1746

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            +I  +   D+ +YTC A N  GEA C+
Sbjct: 1747 IISDVCGDDDAKYTCKAVNSLGEATCT 1773



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 46/151 (30%), Positives = 74/151 (49%), Gaps = 5/151 (3%)

Query: 710  TCRAVSATGVAETKAVLH-VTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ 768
            T  AV A G   + A++  ++ R +   +   P   + ++  ED S+   +   EE+   
Sbjct: 1627 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1686

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827
            +P F + ++DL E+ EG  A F+ ++    DP   V W+KD + I  S      ++  G 
Sbjct: 1687 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1743

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
             SL I  +  +D   YT +AVN LGEA  TA
Sbjct: 1744 CSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1774



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 20/239 (8%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P FI   ++  ++E    +FE RV    +P  ++ W+RNG+ + SG R+     + G  S
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  V+ ED G+Y C A N  G    + T+      ++ ++    + + +      +  
Sbjct: 91   LVIHAVHEEDRGKYTCEATN--GSGARQVTV------ELTVEGSFAKQLGQPVVSKTLG- 141

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
               ++++    T   ++    + PP+F T++  +  + E +  +F C++   G P  +V 
Sbjct: 142  --DRFSASAVETRPSIWG---ECPPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVT 193

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W     PL    R +     G   +    V  +D G Y C   N  G     A +   G
Sbjct: 194  WLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 5/157 (3%)

Query: 983  TCRAYNAIGQATTSANLTIVT-KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            T  A  AIG+ ++ A ++ ++ +K        P   EK++  ED S+       E K   
Sbjct: 1627 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1686

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGY 1100
            KP F   ++   ++VEG +A F+ ++E   D    V W+ + + I  +   Q  Y + G 
Sbjct: 1687 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPD--PEVVWFKDDQSIRESRHFQIDYDEDGN 1743

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             +L I+ V  +D   YT  A N+ GEA  +A   VET
Sbjct: 1744 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVET 1780



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 43/140 (30%), Positives = 65/140 (46%), Gaps = 5/140 (3%)

Query: 4374 GDKEITRKITSTETTE-IEHKAQTQERVVEGPV--KPSKPPIFTKKMQPCRVFEHEQARF 4430
            G K  T   TS    E +E +    +  +E     KP   P F+K ++   V E   ARF
Sbjct: 1648 GRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARF 1707

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489
            + + +G P P + W++++  I+ S  FQI +       LII  V  +D A +   A N  
Sbjct: 1708 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1767

Query: 4490 GTAKCSANLVVEEKRRQGRG 4509
            G A C+A  +V E   +G G
Sbjct: 1768 GEATCTAEHIV-ETMEEGEG 1786



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 59/243 (24%), Positives = 97/243 (39%), Gaps = 17/243 (6%)

Query: 258  RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            RS    + P   QK ++  + EG     Q Q+S +P   + W  NG+ L  + K  I++ 
Sbjct: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1079

Query: 318  HNHT-TLRVRNTQKSDSGHYTLLAENPNG-----CIVTSGYLAVESPTESYVQDQRSQYI 371
                 ++ +      D G Y  +A+N  G     C VT         T++     R    
Sbjct: 1080 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1139

Query: 372  TDTQQRETEERIEISEK---------ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            +      TE    + +K         A+ PQ ++  +D+ V  G+      +VTG     
Sbjct: 1140 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1199

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             TW    +QI+D  + K+  +E+G+  L I        G  T +  NK G    Q  L V
Sbjct: 1200 CTWMKFRKQIQDSEHIKVENSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258

Query: 483  IEK 485
            ++K
Sbjct: 1259 VDK 1261



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 8/123 (6%)

Query: 43  HFTRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPV 102
           H ++   +   S  D  P+T   P    PP      +N    +G  AKFEG++RG P P 
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEA-PAFILPP------RNLCIKEGATAKFEGRVRGYPEPQ 63

Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           V+W R   P+    ++ +    + G  SL+I  +   D G+YTC A N  G    +V + 
Sbjct: 64  VTWHRNGQPITSGGRFLLDCGIR-GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122

Query: 163 PEG 165
            EG
Sbjct: 123 VEG 125



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 61/212 (28%), Positives = 85/212 (40%), Gaps = 26/212 (12%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG     +C V     P +T  W  NGQ I+     R+T + G   L I     ED GTY
Sbjct: 458  EGQDFVLQCSVRGTPVPRIT--WLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPP 2242
             C A N LG+   +C+  V  H             +  R+ E       + V   K + P
Sbjct: 513  TCLAENALGQV--SCSAWVTVHEK-----------KSSRKSEYL-----LPVAPSKPTAP 554

Query: 2243 RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
             F+  L     V +G       QV    +P   + + HNG  +Q +  FH        SL
Sbjct: 555  IFLQGL-SDLKVMDGSQVTMTVQVSG--NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             IQ   PED G Y+ +A N+ G   +   +TV
Sbjct: 612  WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 63/218 (28%), Positives = 91/218 (41%), Gaps = 28/218 (12%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F + L+    V EG+    +C V     P  RI +  NG+ +Q A     T + G   
Sbjct: 445  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYARS---TCEAGVAE 498

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L IQ  +PED G Y+  A NALG  + +  +TV  K S    S++ E             
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSE------------- 541

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            +  P  P   T   P+F Q L ++  + +G       ++   G+P  +V W  N   I++
Sbjct: 542  YLLPVAPSKPT--APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 596

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S            S+ I  V  ED G Y C A N  GE
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGE 634



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 35/237 (14%)

Query: 3558 PEFTTTPSDLILSENSSAHFEC--RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            P F++   D  + E      +C  R  PV     R+ W  NG+P+      ++  + G  
Sbjct: 445  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVP----RITWLLNGQPI---QYARSTCEAGVA 497

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I      D G YTC A N  G+  VSC   V              H K  +   + L
Sbjct: 498  ELHIQDALPEDHGTYTCLAENALGQ--VSCSAWVT------------VHEKKSSRKSEYL 543

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
                     + +   KP  P F   + D + V +G  V    +V   G+P   + W HNG
Sbjct: 544  ---------LPVAPSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 591

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
                     H        +L I  ++  D G YTC A N  G   T A +T     D
Sbjct: 592  NEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 5/115 (4%)

Query: 1953 EKIQYLEDDSR-YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
            EK++  ED S+ +  AV ++   V KP F K I++ EV EG     +  +    DP   V
Sbjct: 1663 EKLESEEDVSQAFLEAVAEEKPHV-KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EV 1719

Query: 2012 EWYCNGRPVQQGHRFKTTYDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
             W+ + + +++   F+  YD  G  +L I     +D   Y CKA N++GEA  T+
Sbjct: 1720 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1774



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 3/130 (2%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +L   ED S+    +  +E     P F+  ++D+ V E  AA F+ ++    DP+  V W
Sbjct: 1664 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1721

Query: 1747 LRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             ++   I  S      +D  G  +L +  V  +D   YTC+A+N LGEA  ++   V++ 
Sbjct: 1722 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETM 1781

Query: 1806 ASLQLESQHE 1815
               + E + E
Sbjct: 1782 EEGEGEGEEE 1791



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 51/226 (22%), Positives = 93/226 (41%), Gaps = 31/226 (13%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F S L +    EG +   +C+V  +  P  +I W  N +P+      +ST +     L I
Sbjct: 447  FSSVLKDCAVIEGQDFVLQCSVRGT--PVPRITWLLNGQPIQYA---RSTCEAGVAELHI 501

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                 ED G YTC A N+ G  + S  +                       V + + +R 
Sbjct: 502  QDALPEDHGTYTCLAENALGQVSCSAWV----------------------TVHEKKSSRK 539

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLE 2955
            ++   P  P    P     +   ++ ++++G  + +  QV    +P  ++ W  NG  ++
Sbjct: 540  SEYLLPVAPSK--PTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQ 595

Query: 2956 QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            +   F         +L + +V+  D+G YTC+A+N  GE  T + +
Sbjct: 596  ESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 53/238 (22%), Positives = 94/238 (39%), Gaps = 12/238 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F   ++D+ VAE +    + ++    DP   + W  NG  ++ +  +    +    +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-------QSKASLQLESQHESALQKIQ 1822
            ++++    ED G Y C A N+ G+A  S  + V        +KA      + +S+L  + 
Sbjct: 1086 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 1823 QLEDSSRYQRREDVEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
              E  +  +++   +     A P  I Q     K+  G+S     ++     P +   W 
Sbjct: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG-TQP-ITCTWM 1203

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
               K +Q     +  N    + L IL    E  G YT    N LG   + + L V  K
Sbjct: 1204 KFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 37/146 (25%), Positives = 68/146 (46%), Gaps = 4/146 (2%)

Query: 1251 TVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            T  AV  +G   + A++  +  R        +    E+++  ED ++   +   +     
Sbjct: 1627 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1686

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD-YV 1368
             P FS+ + ++E VEG+    +C+++   D    V WF + + I+    F+  Y+ D   
Sbjct: 1687 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNC 1744

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEA 1394
            +L +  V  +D   YTC+A N LGEA
Sbjct: 1745 SLIISDVCGDDDAKYTCKAVNSLGEA 1770



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 3/134 (2%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + +  + +G+     + E   S+    PPK A K     ++EG   +F  +++G P+P+V
Sbjct: 133 QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-- 355
           TW K    L  S +  +   +    L +    + D G YT L  N +G    S  L++  
Sbjct: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252

Query: 356 -ESPTESYVQDQRS 368
            +S   S+V++ ++
Sbjct: 253 LDSANRSFVRETKA 266



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 61/232 (26%), Positives = 91/232 (39%), Gaps = 28/232 (12%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F+  +KD   V EG      C V   G P  RI W  NG+P        +  + G   
Sbjct: 445  PSFSSVLKD-CAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPI---QYARSTCEAGVAE 498

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L I      D G YTC A N  G  + +A +T   K+            S  K + L   
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK------------SSRKSEYL--- 543

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
             +  AP +     T P F+  +    ++  +G +    V+   +P   + W  NG  +  
Sbjct: 544  -LPVAPSK----PTAPIFLQGLSD--LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
               +         SL I  V+ ED+G Y C A N  GE  T+A ++ ++  D
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 6/122 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + E+R E   +  AP F +  QD  V EGK     C+V+  P   + W +N + ++    
Sbjct: 1017 DNEKRSE--SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-K 1073

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE---KEQVVAPKFV 494
              IL  E    ++ I    L D G+  CVA+N +G+    C++ V +    E   AP+  
Sbjct: 1074 FIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1133

Query: 495  ER 496
             R
Sbjct: 1134 SR 1135



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 61/244 (25%), Positives = 99/244 (40%), Gaps = 16/244 (6%)

Query: 2226 QGHSTRIEVE---EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
            +GH+   + E   E + + P F  +L+   HV EGK    +CQV    DP   I +  NG
Sbjct: 1010 RGHAGTTDNEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSS--DPPATIIWTLNG 1066

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV----TAKG 2338
            K L++     ++ +    S+ I+  + ED G Y   A N  G    +  +TV     ++ 
Sbjct: 1067 KTLKTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1126

Query: 2339 SIISE--SQRPE-GLEKIRELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTA 2394
            +   E  S+RP+  L  +   ES    K+   P+ P     P           ++ G++ 
Sbjct: 1127 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1186

Query: 2395 HFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
                ++   G   +   W +  K I+DS  I   +      +TI   R E  G Y     
Sbjct: 1187 ELFGKV--TGTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVE 1244

Query: 2455 NLLG 2458
            N LG
Sbjct: 1245 NKLG 1248



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 54/235 (22%), Positives = 91/235 (38%), Gaps = 14/235 (5%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F + L ++   EG  + L+C++    D    + W  NGK +KT      + E    +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV------IAKKDLILESQHP-SGLEKIQ 1422
            + +     ED G+Y C A N  G+A  SC + V         K   ++S+ P S L  + 
Sbjct: 1086 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 1423 YLEDTSRYKKTDI--IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEW 1480
              E  +  KK           + P+ +  P+  + V  G+ V    K+       +   W
Sbjct: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKV--TGTQPITCTW 1202

Query: 1481 FKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             K  + +      +  +      L I+    E  G YT    N +G+ +    LT
Sbjct: 1203 MKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1257



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 53/251 (21%), Positives = 93/251 (37%), Gaps = 10/251 (3%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E   E     P F + LQD+  + EG+    + Q++  SDP   + W  +G+ +  +  I
Sbjct: 1019 EKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFI 1075

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV----AARSTVTADLGIP 875
                     S++I     ED G Y   A N  G+A  +  + V    A+ +T   ++   
Sbjct: 1076 ILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935
              +  +                     P++   P+     +DQ  ++ G       ++  
Sbjct: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ-KVRAGESVELFGKVT- 1193

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             G   +   W+K  + ++ S  I    +     LTI +      G YT    N +G    
Sbjct: 1194 -GTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQA 1252

Query: 996  SANLTIVTKKD 1006
              NLT+V K D
Sbjct: 1253 QVNLTVVDKPD 1263



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 5/100 (5%)

Query: 3687 IEDEKPN-PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
            + +EKP+  P F+  I+D ++V EG    FDC++E   DP   + WF + +         
Sbjct: 1679 VAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQ 1735

Query: 3746 -TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
               ++ G  +L I  +   D  +YTC+A N  G AT TA+
Sbjct: 1736 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1775



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 5/108 (4%)

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            E  +++ +  +    +E+P V   P F   I+   V E    RF+C++E   DP+  + W
Sbjct: 1666 ESEEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1721

Query: 3866 YRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            +++ + +     ++  YD  G  SL I  V  +D  +Y C+AVN  GE
Sbjct: 1722 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1769



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 58/258 (22%), Positives = 90/258 (34%), Gaps = 10/258 (3%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G++GT D        G  P F     D+ ++E      +C++   +D    + W  NGK 
Sbjct: 1011 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKT 1068

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI--IL 3657
            L T   +    +     + I      D GLY C A N  G+A  SC++ V          
Sbjct: 1069 LKTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1128

Query: 3658 EPQLPSHF-KSGTESIQKLEE--TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVH 3714
             P++ S   KS    +   E   T+ K+       +   PP+  ++  ++  V  G  V 
Sbjct: 1129 APEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI-IQFPEDQKVRAGESVE 1187

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
               +V   G   +   W    +       +   N      L I        G YT    N
Sbjct: 1188 LFGKV--TGTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVEN 1245

Query: 3775 KWGSATTTAKITCSAKRD 3792
            K GS      +T   K D
Sbjct: 1246 KLGSRQAQVNLTVVDKPD 1263



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 55/224 (24%), Positives = 86/224 (38%), Gaps = 12/224 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG  +  +C V  S DP   I W  N K L +      + + S  S+ I
Sbjct: 1031 FKQKLQDVHVAEGKKLLLQCQV--SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQ-----GKAGLEAVEQA 2890
                 ED G+Y C A N  G A  S  +    D     +T+ P+      K+ L  V   
Sbjct: 1089 EKALLEDRGLYKCVAKNDAGQAECSCQV-TVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147

Query: 2891 E-EARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949
            E +A + K   P  P      P+ II    + ++  G+ + L G+V       +   W  
Sbjct: 1148 ESDATVKKKPAPKTPPKAAMPPQ-IIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMK 1204

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
              K ++     K+ +      L ++   +   G YT    NK G
Sbjct: 1205 FRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 32/232 (13%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F + ++D   ++EGQ    +  +     P  ++ W  NG+ + +    R+  + G+  
Sbjct: 445  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401
            L I     E+ G Y C+A N LG+ S  A +    K++      L               
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL--------------- 543

Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461
                      V   K  AP+F   LS+++ + +G       +++    P  +V W  NG 
Sbjct: 544  --------LPVAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVSGNPPP--EVIWLHNGN 592

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             ++    F          L I   +PED+G Y C A+N+ GE  T A + VQ
Sbjct: 593  EIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 4/124 (3%)

Query: 2613 PESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            P + E+++ +E       E   +      P F+  ++  + +VEG     + ++E   DP
Sbjct: 1659 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1717

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
              ++ WFK+  ++      +  +D  G  +L I+ +  DD   YTCKA N LGEA  TA 
Sbjct: 1718 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1775

Query: 2732 IKIE 2735
              +E
Sbjct: 1776 HIVE 1779



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 4/120 (3%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            EKL++ ED      +   EE+    P F+  + ++E + EG  A F+ ++    DP  +V
Sbjct: 1663 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV-EGSAARFDCKIEGYPDP--EV 1719

Query: 3455 EWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             W+ + +S++    F+  + + G   L IS    +D  +Y C+A N+ GEA  TA   V+
Sbjct: 1720 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 1779



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 39/109 (35%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 470 KSGETA-FQCR-LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
           K  +T  F+C  L V+E    VAP F        V EG+  VL     GTP PRITW  +
Sbjct: 426 KENQTVKFRCEGLAVME----VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 481

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           G PI      R   + G + L I  A   D   Y C A+N  G  +  A
Sbjct: 482 GQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 527



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 55/226 (24%), Positives = 89/226 (39%), Gaps = 14/226 (6%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F  +L     ++EG+    +C++    DP   + W  NGK L++      S +    
Sbjct: 1028 APAFKQKLQD-VHVAEGKKLLLQCQVSS--DPPATIIWTLNGKTLKTTKFIILSQEGSLC 1084

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-------QSKESIIRDSQHESALEKI 1955
            ++ I     ED G Y C A N+ GQA  S ++ V        +K   ++  + +S+L  +
Sbjct: 1085 SVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144

Query: 1956 QYLEDDSRYKR--AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW 2013
               E D+  K+  A +        PQ  +  ++ +V  G  V L   +T     T    W
Sbjct: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT--CTW 1202

Query: 2014 YCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
                + +Q     K         L IL A  E  G Y     N +G
Sbjct: 1203 MKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 4/100 (4%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GY 966
            KP F   I+D + + EG  A F+ ++E   D    V W KD + +  S      ++  G 
Sbjct: 1687 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1743

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
             +L I  V   D   YTC+A N++G+AT +A   + T ++
Sbjct: 1744 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEE 1783



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 57/243 (23%), Positives = 98/243 (40%), Gaps = 19/243 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L+  + + EG+    + +V   SD   T+ W  NGK + +   I    +    +
Sbjct: 1029 PAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            + I     ED G+Y  VA+N AG+A+ S  +TV+   + + +   +    K+R  + S  
Sbjct: 1086 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT---KAPEMKSRRPKSS-- 1140

Query: 1163 VEPMYQIEEIS--KSKPVFVQP--LSNPPPV---SEGKNIHLECRLEPMGDPT----MRV 1211
            + P+   E  +  K KP    P   + PP +    E + +     +E  G  T    +  
Sbjct: 1141 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1200

Query: 1212 EWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             W    + +      K         L I+ A     G YT+   N LGS      + V++
Sbjct: 1201 TWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260

Query: 1272 RSD 1274
            + D
Sbjct: 1261 KPD 1263



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 3/131 (2%)

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
            E+++  ED S+     + +E     P  + +++++E+ EG  A F+ ++    D   +V 
Sbjct: 1663 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVV 1720

Query: 1613 WYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
            W+ +++ ++    F  + +  G  +L I     +D   YTC+A+N+LGEA  +   IV +
Sbjct: 1721 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVET 1780

Query: 1672 KKSIYLESQHE 1682
             +    E + E
Sbjct: 1781 MEEGEGEGEEE 1791



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 57/243 (23%), Positives = 89/243 (36%), Gaps = 36/243 (14%)

Query: 3031 SLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090
            SL  +P +         P F    +++  I EG  A +E  +   G     + W  NG+ 
Sbjct: 16   SLSVDPSRVDSMPLTEAPAFILPPRNLC-IKEGATAKFEGRV--RGYPEPQVTWHRNGQP 72

Query: 3091 IEASHRIRTVYAF-GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC--------- 3140
            I +  R        G   L I      D G Y+C ATN  G  +++V+L           
Sbjct: 73   ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLG 132

Query: 3141 ---VDKSKGQK-----------------PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
               V K+ G +                 P+F T +  +  +K+GQ   F C +     P 
Sbjct: 133  QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKIT--GRPQ 189

Query: 3181 MKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             ++ W     P++ S R+      G  VL+I      D G Y C   N  G+    A ++
Sbjct: 190  PQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELS 249

Query: 3241 CYG 3243
              G
Sbjct: 250  IQG 252



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           P +P+ PIF Q   + +   G       ++ GNP P V W      + E   +   + ++
Sbjct: 548 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQR 605

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
               SL I+++ P D G YTC A N  GE
Sbjct: 606 GTQHSLWIQEVFPEDTGTYTCEAWNSAGE 634



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 33/130 (25%), Positives = 63/130 (48%), Gaps = 7/130 (5%)

Query: 2201 VAGHRNIILDTQHPNGLEKIRQLE--AQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            ++G ++       P   EK+   E  +Q     +  E+P + P  + ++      V EG 
Sbjct: 1646 LSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP--YFSKTIRDLEVVEGS 1703

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSV 2317
             A F+C++E   DP   + ++ + ++++ +  F I +D  G  SL I     +D  +Y+ 
Sbjct: 1704 AARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1761

Query: 2318 KAINALGHCT 2327
            KA+N+LG  T
Sbjct: 1762 KAVNSLGEAT 1771



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 25/87 (28%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYE 4785
            +RD+ V EG  A+F  +I     P + W ++   I E+  FQ+ + E  N  L+I +   
Sbjct: 1694 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1753

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +D   +TC+A  + G+   +A+ +V++
Sbjct: 1754 DDDAKYTCKAVNSLGEATCTAEHIVET 1780



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 56/231 (24%), Positives = 89/231 (38%), Gaps = 28/231 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P F+ VL   + + EGQ    +  V   G P  R  W +NG  ++     R+T + G   
Sbjct: 445  PSFSSVLKDCAVI-EGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L I   +  D G Y C A N  G                        +W  +  K+++  
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCS-------------------AWVTVHEKKSSRK 539

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                + V      APIF   L    K+++G  V +  QV     P  ++ W  NG  +  
Sbjct: 540  SEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQVTMTVQVSGNPPP--EVIWLHNGNEIQE 596

Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
                         +L I  +  +D+G YTC+A N  GE  + A + +++ H
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 647



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIK 4749
            GD K VA +   + +++              PA + P R++ + EG  A+F+ ++    +
Sbjct: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            P + W R G  I     F ++  G      L+I   +EED G +TC AT  +G  + + +
Sbjct: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 4808 LVVK 4811
            L V+
Sbjct: 121  LTVE 124



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 5/90 (5%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F  + K+    +G +   +  +RG P P ++W     P+    +Y+ R   + G   L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYA-RSTCEAGVAEL 499

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            I+   P D G YTC A N  G+  CS ++
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWV 529



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F+  L  +  M+G ++    ++   G+P  ++ WL NG  I+ S  F    R    SL
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +  +  +D+G YTC A ++ G   T+AVL V
Sbjct: 612 WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 57/237 (24%), Positives = 91/237 (38%), Gaps = 33/237 (13%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F   L+D   + EG++  F  Q +    P  R+ W  +G+PI  +    S    G   
Sbjct: 445  PSFSSVLKDCAVI-EGQD--FVLQCSVRGTPVPRITWLLNGQPIQYAR---STCEAGVAE 498

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L+I     ED G+YT  A N LG+   +A + V  + +         +  Y+        
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-------SRKSEYLLPVA---- 547

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                         P     P F   + D + + +G       ++   G+    V WL +G
Sbjct: 548  -------------PSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 591

Query: 950  RPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
              ++ S            +L I+ V   D G YTC A+N+ G+  T A LT+    D
Sbjct: 592  NEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 27/226 (11%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F   LK    +EG     +  +   G P  +I WL NGQ I+ +    S    G   L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 499

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
            +     +D G YTC A +A G     A + V  + +  +                 S+Y
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK-----------------SEY 542

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
               +  + T+  P F++ L DL ++ +G       Q++   +P   V W  +G  I  S
Sbjct: 543 LLPVAPSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 597

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                       SL I  +  ED G+YT  A N  GE  + A + V
Sbjct: 598 EDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 55/225 (24%), Positives = 97/225 (43%), Gaps = 29/225 (12%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            P F++ +++   + +GQ    +C+V     P  +I W  NGQP++++   ++  + G   
Sbjct: 445  PSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQG 3268
            L I      D G Y C A N  G+    A +  + K      S + + L  +        
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSEYLLPV-------- 546

Query: 3269 AQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG 3328
                 PS P+A  P F+  + D+ K+++G       ++    +P  +V W +NG ++   
Sbjct: 547  ----APSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 597

Query: 3329 HRYRTFHDFGIV-ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              +  F   G    L I   + E++G Y C A N  G   T+A L
Sbjct: 598  EDFH-FEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 11/154 (7%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT-TDSGTYSCRATNKWGQAEISVK-LEC 3140
            +W   G  + A  R+ ++     ++  + G K+ T S T    A     + ++S   LE 
Sbjct: 1623 KWQKTGNAVRAIGRLSSM----AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1678

Query: 3141 VDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199
            V + K   KP F+  I+++E + +G +A F+C +    DP+  + W+ + Q +R S   +
Sbjct: 1679 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQ 1735

Query: 3200 -TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                + G   L I+     D  +Y C+A N  GE
Sbjct: 1736 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1769



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 630  EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            E++ +  P F   ++ +  +EG    F+ +IE   DP  ++ W K+ QSI  S  F   +
Sbjct: 1681 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDY 1738

Query: 690  -RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKA 724
               G  SL +  +   D  +YTC+AV++ G A   A
Sbjct: 1739 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1774



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP F+  L +   + EG++   +  +  T  P  ++ W  NG+ ++     R+ C+ G  
Sbjct: 444  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 497

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQL----PKGMEGTI-- 3532
             L I    PED G Y C A N  G+   +A + V  K++      L    P      I  
Sbjct: 498  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 557

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECR 3580
              ++ L+   G+  T+T +     PPE     +   + E+   HFE R
Sbjct: 558  QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 19/282 (6%)

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQ 1979
            + +  +G A     L   SKE + +D +++   ++      D+  +   Q  +     P 
Sbjct: 976  ETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTA-----PA 1030

Query: 1980 FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDI 2039
            F + +++  V EG  + L+  ++  +DP   + W  NG+ ++       + +    ++ I
Sbjct: 1031 FKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088

Query: 2040 LYAYAEDTGTYMCKATNAVGEAVTTSSVKVD---AKSGLYLDTLDEQRLKKI------QE 2090
              A  ED G Y C A N  G+A  +  V VD   A        +  +R K         E
Sbjct: 1089 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148

Query: 2091 LEKYERPKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
             +   + KP  +  P    P  +      + ++ G+      +V       +T  W    
Sbjct: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMKFR 1206

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            ++I+     +  +      L IL    E  G Y     NKLG
Sbjct: 1207 KQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F   L+    + EG+ + L+ QV   +DP   I W  NG TL T   +  + +  L 
Sbjct: 1028 APAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1084

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            ++SI     +D G+Y C A N  G+A  +  + ++D
Sbjct: 1085 SVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDD 1120



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 51/242 (21%), Positives = 88/242 (36%), Gaps = 12/242 (4%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            E +G AP F   L ++ ++ EG+    + +++   DP   + W  NGK+LK  ++F    
Sbjct: 1023 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT-TKFIILS 1078

Query: 3474 DFGFVI-LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ---GKRNIILESQLPKGME 3529
              G +  + I     ED G Y C A N+ G+A  +  + V       N        +  +
Sbjct: 1079 QEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1138

Query: 3530 GTIDKIAALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
             ++  +   E  +       P+   ++  PP+    P D  +    S     ++      
Sbjct: 1139 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQ 1196

Query: 3588 SMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
             +   W    K +     +K  N      L I    Q   G YT    N+ G       L
Sbjct: 1197 PITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256

Query: 3648 QV 3649
             V
Sbjct: 1257 TV 1258



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 42/151 (27%), Positives = 69/151 (45%), Gaps = 9/151 (5%)

Query: 1127 AQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNP 1186
            A +S     ++ +   TS ++    E    + ++ F+E +   EE    KP F + + + 
Sbjct: 1641 AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQA-FLEAV--AEEKPHVKPYFSKTIRDL 1697

Query: 1187 PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFVALDIIHATSA 1245
              V EG     +C++E   DP   V WF + +S+     F+  YD  G  +L I      
Sbjct: 1698 EVV-EGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1754

Query: 1246 DTGEYTVRAVNHLGSAHTSA--IVRVIERSD 1274
            D  +YT +AVN LG A  +A  IV  +E  +
Sbjct: 1755 DDAKYTCKAVNSLGEATCTAEHIVETMEEGE 1785



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 4078 PKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGH 4137
            P    + EK+   E   Q   E V EE K    P F      + V EG  ARF C++ G+
Sbjct: 1656 PTSPLNAEKLESEEDVSQAFLEAVAEE-KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1714

Query: 4138 PKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P P V+W  +  +I     +++ YD
Sbjct: 1715 PDPEVVWFKDDQSIRESRHFQIDYD 1739



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT--YDGMYHFD 4168
            P F+  P  + ++EG  A+F  RV G+P+P+V W  NG  I +G R+ L     G +   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4169 IPKTRQYDTGK 4179
            I    + D GK
Sbjct: 93   IHAVHEEDRGK 103



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 16/236 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-S 695
            P F   L+ V   EG K+  + ++    DP   I W  NG++++ +++F  + + G + S
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLK-TTKFIILSQEGSLCS 1085

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERT------SQHPE-TLQYIQ 748
            + +    ++D G Y C A +  G AE    + V      E T      S+ P+ +L  + 
Sbjct: 1086 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 749  QLEDYS--KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
              E  +  K +       + +  PQ I+  +D  +++ G +     ++T     T    W
Sbjct: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPIT--CTW 1202

Query: 807  YKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             K  + I  S  I    +     L I+  R E  G YT+   NKLG   +  ++ V
Sbjct: 1203 MKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 16/245 (6%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            +S+G  P F   +Q++  + +G+    +C V    DP   I W  NG+ ++ +  I    
Sbjct: 1023 ESQGTAPAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1079

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATIN----CYGKGGVYLESLQP-D 3255
            +     + I      D G Y C A N  G  E   + T++            ++S +P  
Sbjct: 1080 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1139

Query: 3256 SLAKIRELESLQGAQQQ-TPSTP--SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDP 3312
            SL  +   ES    +++  P TP  +A PP+ I Q  +  K+  G+S     ++      
Sbjct: 1140 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQII-QFPEDQKVRAGESVELFGKVTGTQ-- 1196

Query: 3313 DLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +   W    K++      +  +      L IL   +E+ G Y  +  NKLG    + NL
Sbjct: 1197 PITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256

Query: 3373 KCTSK 3377
                K
Sbjct: 1257 TVVDK 1261



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 40/129 (31%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 44  FTRQMTTQVESS--GDRQPITA--GRP---GEPSPPIFEQIFKNARFAQGGNAKFEGKLR 96
           F +Q+   V S   GDR   +A   RP   GE  PP F          +G   +F  K+ 
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE-CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P V+W +   PL    + S+  +E+ G   L I  +   D G YTC   N  G+A 
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSV--SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243

Query: 157 CSVYIQPEG 165
            S  +  +G
Sbjct: 244 MSAELSIQG 252



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 37/239 (15%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            ++   P F + +K   V E +    +C V  +  P  RI W  NG+ +      R+  + 
Sbjct: 440  VMEVAPSFSSVLKDCAVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 494

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            G   L I     ED G Y C A N  G+      +SC     +       +  ++SE L 
Sbjct: 495  GVAELHIQDALPEDHGTYTCLAENALGQ------VSCSAWVTV----HEKKSSRKSEYL- 543

Query: 3945 QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPN 4004
             +     K T+ ++L                    Q  + L  M+ ++    +   G+P 
Sbjct: 544  -LPVAPSKPTAPIFL--------------------QGLSDLKVMDGSQVTMTVQVSGNPP 582

Query: 4005 MKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
             +V W  NG  +     F         ++    V+PED+G Y C A N  G   T+AV+
Sbjct: 583  PEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 54/241 (22%), Positives = 84/241 (34%), Gaps = 15/241 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  +++D + V EG  +   C+V    DP   I W  NG+   T   +    +    +
Sbjct: 1029 PAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER- 3813
            + I+     D G Y C A N  G A  + ++T          ++ P+  S      L   
Sbjct: 1086 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVD-DAPASENTKAPEMKSRRPKSSLPPV 1144

Query: 3814 -GRISDA-------PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
             G  SDA       PK  P  + PP+ I   +   V   E V    +V   +   +   W
Sbjct: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQ--PITCTW 1202

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             +  K +      +         L IL    E  G Y     N  G    +  ++    P
Sbjct: 1203 MKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262

Query: 3926 D 3926
            D
Sbjct: 1263 D 1263



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/86 (25%), Positives = 41/86 (47%)

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            + Q  AP F ++   ++V EG+ ++L  +    P   I W  +G  +     + +  +G 
Sbjct: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1082

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
              ++ I +A   D   Y+C A+N AG
Sbjct: 1083 LCSVSIEKALLEDRGLYKCVAKNDAG 1108



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            E  G  P F   L  + ++ EG +   +C+V   +DP  TI W  NG+ ++       + 
Sbjct: 1023 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1079

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +    ++ I     ED G Y C A N  G+A  +C + V
Sbjct: 1080 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTV 1118



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD-FSYVSLD 2834
            F   + ++   EG    F+C +E   DP  ++ WF +++ +     ++  +D     SL 
Sbjct: 1690 FSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1747

Query: 2835 ITHTYEEDSGIYTCKATNSKGSAT 2858
            I+    +D   YTCKA NS G AT
Sbjct: 1748 ISDVCGDDDAKYTCKAVNSLGEAT 1771



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 3/115 (2%)

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592
            +K+ + E  S        E +    P F+ T  DL + E S+A F+C++    D    V 
Sbjct: 1663 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VV 1720

Query: 3593 WFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            WF + + +      +   ++ G   L I  V   D   YTCKA N  GEAT + +
Sbjct: 1721 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1775



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNKYS 119
           +T   P + + P F    ++   + G +      + G+P P V W R  KA   +   + 
Sbjct: 641 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 700

Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSV 159
           +  NE     +L++K++ P   G+Y    +N+ GE  C V
Sbjct: 701 VLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQV 738



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++ ++ EG+     C++    DP   + W  N K ++ +  I  + +    S
Sbjct: 1029 PAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            ++I     ED G+Y C A N  G+
Sbjct: 1086 VSIEKALLEDRGLYKCVAKNDAGQ 1109



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 31/109 (28%), Positives = 44/109 (40%), Gaps = 2/109 (1%)

Query: 470  KSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            +S E   Q  L  + +E+  V P F +    L V EG     + +  G P P + W KD 
Sbjct: 1666 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1725

Query: 529  VPIIPNPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
              I  +   +I + + G  +L I      D A Y C A N  G     A
Sbjct: 1726 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1774



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 1/100 (1%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNH 320
            P   P  ++  R+ ++ EG+ A+F  ++ G P P V WFK+ Q +  S   +I      +
Sbjct: 1684 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1743

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             +L + +    D   YT  A N  G    +    VE+  E
Sbjct: 1744 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEE 1783



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 11/104 (10%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERD 2980
            ++VEG     + ++E   DP+  + W+ + + + +   F++  D  G  +L + DV   D
Sbjct: 1698 EVVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1755

Query: 2981 SGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEK 3024
               YTCKA N  GEA       CT+ ++++E  +  +G EG E+
Sbjct: 1756 DAKYTCKAVNSLGEA------TCTA-EHIVETMEEGEG-EGEEE 1791



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 21/92 (22%), Positives = 42/92 (45%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F +K+Q   V E ++   + +   +P   I W      +K +    +    +   + I
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
             +  +ED  ++  VA+N  G A+CS  + V++
Sbjct: 1089 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDD 1120



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 17/240 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP     L++V + EG++   + ++   SD    + W  N K LK+      +      +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV------HSKKSIYLESQH-EGALPRLN 1689
            + I   L ED G Y C A N  G+A  S    V       + K+  ++S+  + +LP + 
Sbjct: 1086 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ--AAHFEARLI--PVGDPKLRVE 1745
              E  +  ++  A        P   MP + I+  E+Q   A     L     G   +   
Sbjct: 1146 GTESDATVKKKPAP----KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W++    I+ S  +   +      L +     E  G YT    N+LG       L V  K
Sbjct: 1202 WMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            +D  K      T P F  +++   V E + +  +C+V    DP   I W  NGK L +  
Sbjct: 1016 TDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTK 1073

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
                  +    S+ I     ED G Y C A ND G+
Sbjct: 1074 FIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQ 1109



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/138 (22%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 3013 TQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASL 3072
            T  P      EK+++ ED  +       ++     P F+   +D+ ++ EG  A ++  +
Sbjct: 1653 TGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKI 1711

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
                D  +V  WF + ++I  S   +  Y   G   L I      D   Y+C+A N  G+
Sbjct: 1712 EGYPDPEVV--WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1769

Query: 3132 AEISVK--LECVDKSKGQ 3147
            A  + +  +E +++ +G+
Sbjct: 1770 ATCTAEHIVETMEEGEGE 1787



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 14/125 (11%)

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPK----FITQIQDVTKLVEGQSAHFEARLVPV 3309
            P S     +LES +   Q      + E P     F   I+D+ ++VEG +A F+ ++   
Sbjct: 1656 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGY 1714

Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHD----FGIVILDILYCYEENSGEYECVATNKLGR 3365
             DP+  V WF + + +     ++  +D      ++I D+  C ++++ +Y C A N LG 
Sbjct: 1715 PDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV--CGDDDA-KYTCKAVNSLGE 1769

Query: 3366 DSTKA 3370
             +  A
Sbjct: 1770 ATCTA 1774



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GF 2565
            KP F++ +    E+ EG  A ++ ++    DP +   W+ +   ++    F+  +D  G 
Sbjct: 1687 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEV--VWFKDDQSIRESRHFQIDYDEDGN 1743

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I+ V  +D   Y CKA+N  G
Sbjct: 1744 CSLIISDVCGDDDAKYTCKAVNSLG 1768



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 10/192 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            T+++     +   P F  ++Q    + E +    +CQ++   DP   + W  NGK L   
Sbjct: 1016 TDNEKRSESQGTAPAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTT 1072

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV------Y 4073
                   +    +++      ED G Y C A N  G  E    +     P          
Sbjct: 1073 KFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEM 1132

Query: 4074 DSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCR 4133
             S+ PK         E +A+ +  P       KA  PP  +  P+   V  GE      +
Sbjct: 1133 KSRRPKSSLPPVLGTESDATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVRAGESVELFGK 1191

Query: 4134 VTGHPKPRVMWL 4145
            VTG       W+
Sbjct: 1192 VTGTQPITCTWM 1203



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 2/90 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+Q  ++   A+G     + ++  +P   + WT     L +  K+ +  +++    S+
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFII-LSQEGSLCSV 1086

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             I++    D G Y C A+N  G+A CS  +
Sbjct: 1087 SIEKALLEDRGLYKCVAKNDAGQAECSCQV 1116



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 2232 IEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL-QSAA 2289
            + V+EP   + P F+++ R  T    G++    C +    DP   + +  +GKAL +   
Sbjct: 641  LTVQEPHDGTQPWFISKPRSVTASL-GQSVLISCAI--AGDPFPTVHWLRDGKALCKDTG 697

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS-MTVTAKGSIISESQRPE 2348
             F +  +    +L ++   P  AG+Y +   N +G C+  +S M   +    +   + P 
Sbjct: 698  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 757

Query: 2349 GLEKI 2353
              E +
Sbjct: 758  SCEDL 762



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 13/120 (10%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL--PSGHRYR 3879
            +EP   T P FI++ +S T    + V   C +    DP   + W R+GK L   +GH + 
Sbjct: 644  QEPHDGTQPWFISKPRSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGH-FE 700

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
             + +    +L +  V    +G+Y     N  GE        C     ++LQN   R + R
Sbjct: 701  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--------CSCQVSLMLQNSSARALPR 752



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 33/88 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P+ ++      VR GE V L  +  GT     TW K    I  +  +++      S L I
Sbjct: 1169 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTI 1228

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A+      Y    +N  GS   +  L
Sbjct: 1229 LAARQEHCGCYTLLVENKLGSRQAQVNL 1256



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 1738 GDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            GDP   V WLR+G  + + +     + +     L +K V P  +G Y     N +GE   
Sbjct: 677  GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 736

Query: 1797 SSTLFVQSKASLQLESQHESA 1817
              +L +Q+ ++  L    E A
Sbjct: 737  QVSLMLQNSSARALPRGREPA 757



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
            +E+RSE    +   P F Q L     + EG+    + +V    DP     W +NG  LK 
Sbjct: 1018 NEKRSES---QGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT 1071

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                  + +    ++ I   +  D GLY C A N AG
Sbjct: 1072 TKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAG 1108


>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
            isoform 2 protein.
          Length = 1845

 Score =  175 bits (427), Expect = 2e-42
 Identities = 185/750 (24%), Positives = 299/750 (39%), Gaps = 58/750 (7%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGE 4045
            E  T KFE ++   G P  +V W  NG+P+    RF       G  ++    V+ ED G+
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 4046 YLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEES 4105
            Y C ATN  G  +    +   G     +  QL + + S        AS   T   +  E 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE- 158

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGM 4164
               CPP F +    V V+EG+  RF C++TG P+P+V WL     +   +R  ++  +GM
Sbjct: 159  ---CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGM 215

Query: 4165 YHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQY 4224
               +I    Q D G    +             L +       +G L +A R +  ET   
Sbjct: 216  QVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI-------QG-LDSANRSFVRET--- 264

Query: 4225 QRTETELEKTFEERQVLQRQGVIDH-RPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE 4283
            + T +++ K  E   V+ ++  +D      K K    P+             +     +E
Sbjct: 265  KATNSDVRK--EVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ---PPRE 319

Query: 4284 LENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQ 4343
             + E      R    T         +T    A+   +     L       E+R +    +
Sbjct: 320  SKLESCKDSPRTAPQTPVLQKTSSSITLQA-ARVQPEPRAPGLGVLSPSGEERKRPAPPR 378

Query: 4344 KPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEG 4403
                P           V  A  ++   E   D    +  +  ++ E++   QT +   EG
Sbjct: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKEN-QTVKFRCEG 437

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
                   P F+  ++ C V E +    +    G P+P I W     PI+ +   +    +
Sbjct: 438  LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEA 494

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG-IVP--------P 4514
              + L I+    ED   +  +AEN  G   CSA + V EK+   +   ++P        P
Sbjct: 495  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLI 4573
             F     ++ V  G  V +  +V+G  P +V WL NG ++Q +  +   E+ GT ++L I
Sbjct: 555  IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLWI 613

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
             E +P+D+G Y C A NSAGE R  A   V       +P   T+     P  I   +   
Sbjct: 614  QEVFPEDTGTYTCEAWNSAGEVRTQAVLTV------QEPHDGTQ-----PWFISKPRSVT 662

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             + GQ++  SC I G P PTV W + G  L K + +F++ +  D +TL + +  P   G 
Sbjct: 663  ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
            Y+ +  N  G  +    L + Q   A  LP
Sbjct: 723  YEILLKNRVGECSCQVSL-MLQNSSARALP 751



 Score =  142 bits (345), Expect = 2e-32
 Identities = 163/650 (25%), Positives = 263/650 (40%), Gaps = 59/650 (9%)

Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFG 1633
            T+AP      +N+ IKEG  A FE R+    +   +V W+ N +P+ SG RF  +    G
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 1634 FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLED 1693
              +L I +   ED G YTC A N  G    +    V    +  L  Q   +    ++   
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQL-GQPVVSKTLGDRFSA 146

Query: 1694 TSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753
            ++   R S   E     P F   +  + V E Q   F  ++   G P+ +V WL+  VP+
Sbjct: 147  SAVETRPSIWGEC---PPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPL 201

Query: 1754 EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ----SKASLQ 1809
            + S R++     G   L +  VN +D G YTC  +N  G+A  S+ L +Q    +  S  
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261

Query: 1810 LESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNG-PTKLSEGQ------SA 1862
             E++  ++  + +     S+  + + +E A         Q  G P   +  Q      S 
Sbjct: 262  RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321

Query: 1863 HYECRIEPYPDPNMRVEWYFNGKV-LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
               C+  P   P   V    +  + LQ+    R   +     L +L+  GE+        
Sbjct: 322  LESCKDSPRTAPQTPVLQKTSSSITLQAA---RVQPEPRAPGLGVLSPSGEERKRPAPPR 378

Query: 1922 INNLGQAVSSI-RLNVQSKES---IIRDSQHESALEKI------QYLEDDSRYKRAVQDD 1971
                      +   +V SK +   I  + Q +SA  K       Q ++++   K   +  
Sbjct: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGL 438

Query: 1972 SFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031
            + +   P F   +K+  V EG    L+ ++     P  R+ W  NG+P+Q     ++T +
Sbjct: 439  AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCE 493

Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQEL 2091
             G   L I  A  ED GTY C A NA+G+   ++ V V  K                +  
Sbjct: 494  AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK----------------KSS 537

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
             K E   P+   +P   P+FL  L+   +LK  D +     V+   +P   + W HNG +
Sbjct: 538  RKSEYLLPVAPSKP-TAPIFLQGLS---DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593

Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            I+    +         +L I   + ED+GTY C+A N  GE      L V
Sbjct: 594  IQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score =  131 bits (317), Expect = 5e-29
 Identities = 86/307 (28%), Positives = 135/307 (43%), Gaps = 7/307 (2%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V PSF+   ++  V  GQ   L   V GT    + WL NG+ +Q   R+    E G   L
Sbjct: 443  VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTC--EAGVAEL 499

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK---PQTKAANAPPEIIEP 4628
             I +A P+D G Y C+A N+ G+  C A   V    +  K +   P   +    P  ++ 
Sbjct: 500  HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L D  V +G  +  + ++ G P P V W      I+ S+ F   +   +++L I E FPE
Sbjct: 560  LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPE 619

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            D G Y C A+NSAG V   A L V +P        ++  R +    GQ       I    
Sbjct: 620  DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 679

Query: 4749 KPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             PT+ WLR+G AL  +T  F+++   +   L++        G +        G+      
Sbjct: 680  FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739

Query: 4808 LVVKSKT 4814
            L++++ +
Sbjct: 740  LMLQNSS 746



 Score =  109 bits (261), Expect = 3e-22
 Identities = 78/314 (24%), Positives = 129/314 (41%), Gaps = 19/314 (6%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P  +   ++  + EG D   Q  + G P PR+TW  NGQ +  +             L +
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHI 501

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
           ++    D G YT LAEN  G +  S ++ V     S    ++S+Y+              
Sbjct: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----RKSEYLLPVAP--------- 548

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
             K  AP F++   D  V +G       +V+G P PEV W  N  +I++  +        
Sbjct: 549 -SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRG 606

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
             H+L I  V   D+G  TC A N +GE   Q  L V E      P F+ +  ++    G
Sbjct: 607 TQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLG 666

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           + V+++    G P P + W +DG  +  +     +  +    TL + + +   A  Y+  
Sbjct: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 726

Query: 565 AQNVAGSTATRARL 578
            +N  G  + +  L
Sbjct: 727 LKNRVGECSCQVSL 740



 Score =  107 bits (258), Expect = 7e-22
 Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 14/235 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-G 3476
            +AP F +P  N+  ++EG  A FE R+    +P  +V W+ NG+ + +G RF   C   G
Sbjct: 31   EAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 3477 FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIA 3536
               L I   + ED G+Y C A N  G    T  + V+G        QL + +   + K  
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPV---VSKTL 140

Query: 3537 ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
                 +  V+T  P      PP+F T    +++ E     F C++        +V W   
Sbjct: 141  GDRFSASAVET-RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
              PL   +RV      G  +LEI GV Q D G+YTC   N  G+A++S +L ++G
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score =  102 bits (244), Expect = 4e-20
 Identities = 76/245 (31%), Positives = 112/245 (45%), Gaps = 10/245 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDF 1765
            +T+AP F +P +++ + E   A FE R+   G P+ +V W RNG PI +  R L      
Sbjct: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G  +L +  V+ ED G YTC A N  G    +  L V+   + QL     S  + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS--KTLGDRF 144

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             +S  + R  +       P+F T+L G   + EGQ   + C+I   P P  +V W     
Sbjct: 145  SASAVETRPSIWGEC--PPKFATKL-GRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNV 199

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
             LQ   R   S   G   L+I  V  +D G YTC  +N  G+A  S  L++Q  +S  R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 1946 SQHES 1950
               E+
Sbjct: 260  FVRET 264



 Score =  100 bits (240), Expect = 1e-19
 Identities = 68/246 (27%), Positives = 114/246 (46%), Gaps = 5/246 (2%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           +   ++ ++ + +      S+     P     PRN  ++EGA A+F+ ++ G P P+VTW
Sbjct: 7   VASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTW 66

Query: 300 FKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-S 357
            +NGQ + +  +  +      T +L +    + D G YT  A N +G    +  L VE S
Sbjct: 67  HRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126

Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
             +   Q   S+ + D       E          P+F        V EG+M RF C++TG
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNE-SGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
           RP P+VTW   +  ++   + ++ V+E +G   L I  V   D GV TC+  N SG+ + 
Sbjct: 187 RPQPQVTWLKGNVPLQP--SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244

Query: 477 QCRLNV 482
              L++
Sbjct: 245 SAELSI 250



 Score =  100 bits (240), Expect = 1e-19
 Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 8/219 (3%)

Query: 4404 PVKPSKP--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            PV PSKP  PIF + +   +V +  Q    V+  G P P + W      I+ S DF    
Sbjct: 545  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 604

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
              T+  L I++VF ED+  +   A N  G  +  A L V+E    G      P F    +
Sbjct: 605  RGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP-HDG----TQPWFISKPR 659

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQD 4580
            +V  + GQ V +   + G     V+WL++GK +  D  + ++L+ +  +TL++ +  P  
Sbjct: 660  SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +G+YE +  N  GE  C    ++   + +  P+ +  A+
Sbjct: 720  AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPAS 758



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 19/225 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P+F L  +N+ +  G   + + +V G     V W +NG+ +    R  +     GT++L+
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP---------------QTK 4617
            I   + +D GKY C A N +G  +   E  V     K   +P               +T+
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4618 AA---NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             +     PP+    L   +V EGQ   FSCKI G+P P V W KG+  ++PS    +S  
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
                 L I     +D G Y C+  N +G+ +++A+L +   D A+
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 18/246 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-VKTINDFGFVI 3616
            P F   P +L + E ++A FE R+    +   +V W  NG+P+ +G R +      G   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V++ D G YTC+ATN  G   V+ +L V+G        QL     S T   +   
Sbjct: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSA 146

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
              +  R  I  E     PP+F  ++   + V EG    F C++   G P  ++ W     
Sbjct: 147  SAVETRPSIWGEC----PPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNV 199

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC----SAKRD 3792
            P    +RV      G   L+I  +   D G YTC   N  G A+ +A+++     SA R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 3793 IVLESQ 3798
             V E++
Sbjct: 260  FVRETK 265



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 72/227 (31%), Positives = 98/227 (43%), Gaps = 26/227 (11%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP  ++ LK+  + EGQ   F  +         ++ W  N +P++      E    G   
Sbjct: 444  APSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---GVAE 498

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696
            L I   LPED GTYTC A NALG+   S    VH KKS     + E  LP        SK
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS---SRKSEYLLPVA-----PSK 550

Query: 1697 YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
                         AP+F   + D++V +        ++   G+P   V WL NG  I+ S
Sbjct: 551  -----------PTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 597

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
                        +L ++ V PED+GTYTC A N  GE  T + L VQ
Sbjct: 598  EDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 59/203 (29%), Positives = 85/203 (41%), Gaps = 18/203 (8%)

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           +AP F  V +D  V EG+     C V G P P +TW +N + I+  Y       E+G   
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTC--EAGVAE 498

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE--------------QVVAPKFVE 495
           L I +    D G  TC+A N  G+ +    + V EK+              +  AP F++
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
             S L V +G  V +  +  G P P + W  +G  I  + +      G   +L I     
Sbjct: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFP 618

Query: 556 SDAAWYQCTAQNVAGSTATRARL 578
            D   Y C A N AG   T+A L
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 16/225 (7%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGFIALDIDYIYA 3762
            N+ + EG    F+ RV   G P  ++ W  NG+P  +G R +      G  +L I  ++ 
Sbjct: 41   NLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS-DAPK 3821
             D G+YTC ATN  G+   T ++T           QL Q +  + + +    R S  A +
Sbjct: 99   EDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGD----RFSASAVE 150

Query: 3822 EEPIV--STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              P +    PPKF T++    V+E +  RF C++  +  P  ++ W +    L    R  
Sbjct: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVS 208

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
                 G   L+I  V  +D G Y C  VN  G+    A +S + L
Sbjct: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 18/242 (7%)

Query: 2899 RRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS 2958
            R  S+P TE   P +I+P      + EG     EG+V  +  P+ ++ W+ NG+ +  G 
Sbjct: 23   RVDSMPLTE--APAFILP-PRNLCIKEGATAKFEGRV--RGYPEPQVTWHRNGQPITSGG 77

Query: 2959 RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK 3017
            RF L     G  +L +  V+E D G YTC+A N  G      TV  T + +  ++   P 
Sbjct: 78   RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPV 135

Query: 3018 GTEGLEKIQNLEDSLRKEPGQQPDDDTGR-PPEFTTVFKDIVDISEGQIAHYEASLIPTG 3076
             ++       L D       +      G  PP+F T    +V + EGQ+  +   +  TG
Sbjct: 136  VSK------TLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKI--TG 186

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
                 + W      ++ S R+      GM VLEI G    D G Y+C   N  G+A +S 
Sbjct: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246

Query: 3137 KL 3138
            +L
Sbjct: 247  EL 248



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 70/260 (26%), Positives = 115/260 (44%), Gaps = 36/260 (13%)

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            EKR + +G    P+F    Q+V+V  G+ + L  +V+   P  + W  NGK ++   +  
Sbjct: 1019 EKRSESQG--TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFI 1075

Query: 4562 ILEEDGTYTLLILE-AYPQDSGKYECVAINSAGEARCDAECVV-SLPATKDKPKPQTK-- 4617
            IL ++G+   + +E A P+D G Y+CVA N AG+A C  +  V   PA+++   P+ K  
Sbjct: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135

Query: 4618 ----------------------AANAPP------EIIEPLKDKIVAEGQAIEFSCKIVGK 4649
                                  A   PP      +II+  +D+ V  G+++E   K+ G 
Sbjct: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
               T  W K  K I+ S++ ++  + +   L I  A  E  G Y  +  N  G       
Sbjct: 1196 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1255

Query: 4710 LKVT-QPDQADNLPALTPLR 4728
            L V  +PD     P  + +R
Sbjct: 1256 LTVVDKPDPPAGTPCASDIR 1275



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 62/249 (24%), Positives = 111/249 (44%), Gaps = 12/249 (4%)

Query: 617 HVERARPYIPPGEEDRV--YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLK 674
           H+ +    + P   D +     P FI+P +++   EG    FE R+   G P  ++ W +
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHR 68

Query: 675 NGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
           NGQ I +  RF       G  SL + +++ +D G+YTC A + +G  +    + +T   +
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV--TVELTVEGS 126

Query: 734 IERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQ 793
             +    P   + +      S  + + SI  +    P+F   L  +  ++EG+   F  +
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECP--PKFATKLGRV-VVKEGQMGRFSCK 183

Query: 794 LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           +T    P  +V W K   P+  S+R++     G   L I  +  +D G YT   VN  G+
Sbjct: 184 IT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241

Query: 854 AISTASIRV 862
           A  +A + +
Sbjct: 242 ASMSAELSI 250



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 65/228 (28%), Positives = 99/228 (43%), Gaps = 14/228 (6%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            +T  P F+  P+++  + EG    FE ++    +   +V W +NGQP+T G RF      
Sbjct: 29   LTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGI 85

Query: 1500 -GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI-QV 1557
             G  +L I  +  ED G YTC A N  G  +V+  LT         S   + G   + + 
Sbjct: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG------SFAKQLGQPVVSKT 139

Query: 1558 LEDRSKYHRTDMVDEVTTQAPI-CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            L DR      +    +  + P    T L  V +KEGQ   F  ++        +V W   
Sbjct: 140  LGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            N PL+  +R + +   G   L+I     +D G YTC  +N  G+A  S
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 77/273 (28%), Positives = 118/273 (43%), Gaps = 33/273 (12%)

Query: 1671 SKKSIYLESQHEGALPRLN---QLEDTSKYQRHSAQDE---VITQAPVFTMPMKDIRVAE 1724
            + + I +E Q + A P+     Q ++  + Q    + E   V+  AP F+  +KD  V E
Sbjct: 399  ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIE 458

Query: 1725 NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYT 1784
             Q   F  +    G P  R+ WL NG PI+ + R T   + G   L+++   PED GTYT
Sbjct: 459  GQ--DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAELHIQDALPEDHGTYT 513

Query: 1785 CRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAP 1844
            C A N LG+   S+ + V  K S                   S + +    V  +   AP
Sbjct: 514  CLAENALGQVSCSAWVTVHEKKS-------------------SRKSEYLLPVAPSKPTAP 554

Query: 1845 RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAAL 1904
             F+  L+   K+ +G       ++   P P   V W  NG  +Q    +         +L
Sbjct: 555  IFLQGLSD-LKVMDGSQVTMTVQVSGNPPPE--VIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 1905 DILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             I  V+ ED+G YTC+A N+ G+  +   L VQ
Sbjct: 612  WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 15/244 (6%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF- 964
            T+ P F  P ++ + IKEG  A FE R+   G    +V W ++G+P+ +  R        
Sbjct: 30   TEAPAFILPPRN-LCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
            G  +L I +V   D G YTC A N  G    +  LT+  +     +   P   + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRF 144

Query: 1025 DASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEWYFN 1082
             AS  +  T   +     P+F   L G   + EGQ   F  ++   PQ  +T    W   
Sbjct: 145  SAS--AVETRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVT----WLKG 197

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
               +  + R+      G   L+I  V  +D GVYT +  N +G+A +SA ++++   S +
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257

Query: 1143 TSSI 1146
             S +
Sbjct: 258  RSFV 261



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 39/107 (36%), Positives = 57/107 (53%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            E +   +  + P F K  +D +V EG   RFDC++ G P PEV WF +D+ IR+  + +I
Sbjct: 1729 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1788

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
              +E GN +L+I++V   D    TC A N  GE      L V   E+
Sbjct: 1789 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1835



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 11/215 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGI 2714
            EG     E +V    +P  ++ W +NG  +T+G R        G  +L I+++  +D G 
Sbjct: 46   EGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2715 YTCKATNLLGEAVSTASIKIEDRHWL-LGESLHPDSL-DRIGALXXXXXXXXXXXXXXXX 2772
            YTC+ATN  G    T  + +E      LG+ +   +L DR  A                 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA----SAVETRPSIWGEC 159

Query: 2773 XXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS 2832
               F + L  +V KEG    F C +     P  ++ W   N PL    R   +       
Sbjct: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQV 217

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            L+I    ++D G+YTC   N  G A+ S  L   G
Sbjct: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 14/252 (5%)

Query: 1970 DDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            D   + E P F  P +N  + EG     E  +    +P  +V W+ NG+P+  G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLD 82

Query: 2030 YDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYL-DTLDEQRLKK 2087
                G  +L I   + ED G Y C+ATN  G    T  + V+      L   +  + L  
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                   E    I  E P   P F T L  +  +KEG    F C++     P +T  W  
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKITGRPQPQVT--WLK 196

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG---- 2203
                ++   R   +   G   L+I     +D G Y C   N  G+A  +  L + G    
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256

Query: 2204 HRNIILDTQHPN 2215
            +R+ + +T+  N
Sbjct: 257  NRSFVRETKATN 268



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 61/225 (27%), Positives = 102/225 (45%), Gaps = 13/225 (5%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P    P F+   R    + EG TA FE +V    +P  ++ ++ NG+ + S  RF +   
Sbjct: 28   PLTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCG 84

Query: 2297 F-GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRE 2355
              G  SL I     ED G+Y+ +A N  G     +++ +T +GS   +  +P   + + +
Sbjct: 85   IRGTFSLVIHAVHEEDRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2356 LESAEPFK-RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
              SA   + RP I        P F   L  +  ++EGQ   F C++   G P  +V W +
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKI--TGRPQPQVTWLK 196

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                ++ S+R++ +   G   + I  V  +D GVY C   N  G+
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 26/240 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++ P F    +   + E   A+FE    G P P + W+R   PI +   F +      + 
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE------------------------E 4502
             L+I  V  ED   +   A N  G  + +  L VE                         
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149

Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
            + R    G  PP F      V V  GQ+ R   K+TG     V WLK    +QP  R  +
Sbjct: 150  ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE-CVVSLPATKDKPKPQTKAANA 4621
             E++G   L I      D G Y C+ +N +G+A   AE  +  L +       +TKA N+
Sbjct: 210  SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 10/224 (4%)

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
            + + D  C      T D  K ++++    P   + L+D  VAEG+ +   C++   P  T
Sbjct: 1001 DVKNDVNCKRGHAGTTDNEK-RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1059

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W    K +K +K+  +S+     ++ I +A PED G YKCVA N AG+   + ++ V 
Sbjct: 1060 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD 1119

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQ--ITSKIKPTIQWLREGALIPET---PDFQ 4768
                ++N  A   ++        P    T+   T K KP  +   + A+ P+    P+ Q
Sbjct: 1120 DAPASENTKA-PEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1178

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  G  +V L G      T   TC       Q++ S  + V++
Sbjct: 1179 KVRAG-ESVELFGKV--TGTQPITCTWMKFRKQIQESEHMKVEN 1219



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 1/98 (1%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLR 4681
            P   + ++D  V EG A  F CKI G P P V W+K D+ I+ S++FQ+    D   +L 
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
            IS+   +D+  Y C A NS G  T  A+L V   ++ +
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1837



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 71/270 (26%), Positives = 105/270 (38%), Gaps = 23/270 (8%)

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G V  VA +   +T+     + ++   +  AP F+     L ++EG       R  G P 
Sbjct: 2   GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 520 PRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P++TW ++G PI       +     G  +L I      D   Y C A N +G     AR 
Sbjct: 62  PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG-----ARQ 116

Query: 579 YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQ 638
                       K+L  P  +K                 VE  RP I  GE      PP+
Sbjct: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSASA-------VE-TRPSI-WGE-----CPPK 162

Query: 639 FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDM 698
           F   L  V   EG    F  +I   G P  ++ WLK    ++ S+R +   + G   L++
Sbjct: 163 FATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220

Query: 699 LSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +N  D G YTC  V+ +G A   A L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 66/240 (27%), Positives = 97/240 (40%), Gaps = 28/240 (11%)

Query: 1303 EDITVMQ-APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
            E + VM+ AP FS  L +   +EG +  L+C ++  G    R+ W  NG+PI+     R 
Sbjct: 436  EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RS 490

Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
              E     L +    PED G YTC A N LG+   S  + V  KK             K 
Sbjct: 491  TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKS 540

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
            +YL   +  K T          P F+     ++ V++G  V    ++    +   +V W 
Sbjct: 541  EYLLPVAPSKPT---------APIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWL 588

Query: 1482 KNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541
             NG  +     F         +L I ++  ED+G YTC A N  G       LT +   D
Sbjct: 589  HNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 1/93 (1%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYT 4570
            V P F+ T +++ V  G   R D K+ G    +V W K+ + ++     +I  +EDG  +
Sbjct: 1738 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1797

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            L+I +    D  KY C A+NS GEA C AE +V
Sbjct: 1798 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 64/250 (25%), Positives = 102/250 (40%), Gaps = 11/250 (4%)

Query: 3125 ATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKI 3183
            A++   +  +SV    VD     + P F    +N+  +K+G +A FE  V    +P  ++
Sbjct: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QV 64

Query: 3184 EWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             W+ NGQP+    R        G   L I      D G+Y C A N  G    + T+   
Sbjct: 65   TWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELT 122

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +G    +  QP     + +  S    + + PS     PPKF T++  V  + EGQ   F
Sbjct: 123  VEGSFAKQLGQPVVSKTLGDRFSASAVETR-PSIWGECPPKFATKLGRVV-VKEGQMGRF 180

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
              ++     P  +V W      L    R       G+ +L+I    +++ G Y C+  N 
Sbjct: 181  SCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238

Query: 3363 LGRDSTKANL 3372
             G+ S  A L
Sbjct: 239  SGKASMSAEL 248



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
            +K++  ED S+       E   +  P F   +    ++ EG +A ++C+IE YPDP   V
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPE--V 1771

Query: 1879 EWYFNGKVLQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             W+ + + ++    ++   D  G  +L I  V G+D  +YTCKA+N+LG+A  +  L V+
Sbjct: 1772 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831

Query: 1938 SKE 1940
            + E
Sbjct: 1832 TME 1834



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 64/248 (25%), Positives = 99/248 (39%), Gaps = 10/248 (4%)

Query: 1303 EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPA 1362
            + + + +AP F     N+   EG     E R++  G    +V W  NG+PI +G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLD 82

Query: 1363 YEF-DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
                   +L + +V+ ED G YTC+ATN  G       + +  +     +   P   + +
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPVVSKTL 140

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
                  S  +    I       P+F T+   +  V EGQ   F CK+        +V W 
Sbjct: 141  GDRFSASAVETRPSIWGECP--PKFATKLGRVV-VKEGQMGRFSCKITGRPQP--QVTWL 195

Query: 1482 KNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541
            K   P+    R       G   L+I  +  +D G+YTC  VN  G   +S  L+ +    
Sbjct: 196  KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255

Query: 1542 IVRSTQNE 1549
              RS   E
Sbjct: 256  ANRSFVRE 263



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/243 (23%), Positives = 99/243 (40%), Gaps = 35/243 (14%)

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-- 425
           S +I+ T       R++      AP F+   ++  + EG   +F+ RV G P P+VTW  
Sbjct: 9   SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68

Query: 426 ----------FINDRQIRDDYN---HKILVNESGNHALMITN--------VTLSDSG--- 461
                     F+ D  IR  ++   H +   + G +    TN        V L+  G   
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128

Query: 462 ------VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
                 VV+    ++   +A + R ++  +     PKF  +   + V+EG+    + +  
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGE---CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           G P P++TW K  VP+ P+  + +    G   L+I      D   Y C   N +G  +  
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245

Query: 576 ARL 578
           A L
Sbjct: 246 AEL 248



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 59/227 (25%), Positives = 90/227 (39%), Gaps = 10/227 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+ P  N   + EG     E R+   G P  +V W  NG+ +T G RF          
Sbjct: 33   PAFILPPRNLC-IKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 1237 LDIIHAT-SADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
              +IHA    D G+YT  A N  G+   + +   +E S      Q  Q +    L +  +
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVT-VELTVEGSFA---KQLGQPVVSKTLGDRFS 145

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                + R  I     P+F+  L  +   EG      C++   G    +V W     P++ 
Sbjct: 146  ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQP 203

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
              R   + +     L++  V  +D GVYTC   N  G+A  S  L +
Sbjct: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/217 (26%), Positives = 91/217 (41%), Gaps = 14/217 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGL 2580
            EG  A +E RV   G P  +  W+ NG  +  G RF       G  +L I++V   D G 
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2581 YMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQI--QLKEAAMNKVPEMFVDTGV 2638
            Y C+A N +G                  Q  +P   + +  +   +A+   P ++ +   
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFA--KQLGQPVVSKTLGDRFSASAVETRPSIWGEC-- 159

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
               P F T L     + EGQ      ++  R  P  ++ W K  V L   AR+  +   G
Sbjct: 160  --PPKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNG 214

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            +  L I+ +  DD G+YTC   N  G+A  +A + I+
Sbjct: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 68/272 (25%), Positives = 110/272 (40%), Gaps = 33/272 (12%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDIID------ESVTIKPRFVTRPKSIENVI 1457
            A + + +E Q  S   K +    +   K+   +         + + P F +  K    VI
Sbjct: 399  ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA-VI 457

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EGQ    +C +        ++ W  NGQP+      R   + G   L I D + ED G Y
Sbjct: 458  EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512

Query: 1518 TCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
            TC A N +G  +VSC  +   T    +S++             +S+Y       + T  A
Sbjct: 513  TCLAENALG--QVSC--SAWVTVHEKKSSR-------------KSEYLLPVAPSKPT--A 553

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            PI    L ++++ +G +     ++    +   +V W HN   ++    F         +L
Sbjct: 554  PIFLQGLSDLKVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
             I    PED+GTYTC A N+ GE  T  +  V
Sbjct: 612  WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 6/119 (5%)

Query: 1415 PSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            P   EK++  ED S+     + +E   +KP F    + +E V+EG    F+CK+E   D 
Sbjct: 1711 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1769

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
              +V WFK+ Q +     F+  +D  G  +L I D+  +D   YTC+AVN +G  E +C
Sbjct: 1770 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATC 1824



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 6/103 (5%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            + EE+P  +P F   +  LE + EG  A F+C++E   DP +   WF + Q IR    ++
Sbjct: 1731 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQ 1787

Query: 2160 TTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              +D  G  +L I     +D   Y CKA N LGEA  TCT ++
Sbjct: 1788 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCTAEL 1828



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 62/234 (26%), Positives = 99/234 (42%), Gaps = 14/234 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            FI    N+  KEG    FE  V    +P  ++ W  N +P+ SG R+          SL 
Sbjct: 35   FILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I   +EED G YTC+ATN  G+   +  L   G     F  Q  Q        ++   + 
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSAS- 147

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
             A   RPS+   E P P++   +     + EGQ+     ++  +  P  ++ W      L
Sbjct: 148  -AVETRPSIWG-ECP-PKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPL 201

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            +  +R  ++   G   L++  V + D G+YTC   N  G+A  S+ +     D+
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 53/219 (24%), Positives = 93/219 (42%), Gaps = 30/219 (13%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLR 4681
            P  I P ++  + EG   +F  ++ G P P V W++ G  +    ++         ++L 
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4682 ISEAFPEDEGDYKCVAYNSAG--RVTVAAKLK------VTQPDQADNL------------ 4721
            I     ED G Y C A N +G  +VTV   ++      + QP  +  L            
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4722 PAL---------TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
            P++         T L  +VV EGQ  +F  +IT + +P + WL+    +  +    +  +
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                VL I    ++D G +TC     +G+   SA+L ++
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 67/267 (25%), Positives = 104/267 (38%), Gaps = 22/267 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F++V KD   I EGQ    + S+   G     I W  NG+ I+ +   R+    G+  
Sbjct: 445  PSFSSVLKDCAVI-EGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQ-----------KPRFTTHIQ 3156
            L I      D GTY+C A N  GQ   S  +   +K   +           KP     +Q
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             +  LK    +    TV    +P  ++ W HNG  ++ S             L I     
Sbjct: 559  GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFP 618

Query: 3217 HDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPST 3276
             D+G Y C A+N  GE  T+A +          +  QP  ++K R + +  G        
Sbjct: 619  EDTGTYTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWFISKPRSVTASLGQSVLISCA 674

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFE 3303
             + +P   +  ++D   L +  + HFE
Sbjct: 675  IAGDPFPTVHWLRDGKALCK-DTGHFE 700



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 59/227 (25%), Positives = 96/227 (42%), Gaps = 27/227 (11%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++ AP F++ LK    ++EGQ   L+  V  R  P  +I W  NG  +      +ST + 
Sbjct: 441  MEVAPSFSSVLKDC-AVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 494

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI-EDRHWLLGESLHPDSLDRIGAL 2756
            G+  L I     +D G YTC A N LG+   +A + + E +     E L P +  +  A 
Sbjct: 495  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA- 553

Query: 2757 XXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL 2816
                              +F+  L+++   +G  +     V+ S +P  ++ W  N   +
Sbjct: 554  -----------------PIFLQGLSDLKVMDGSQV--TMTVQVSGNPPPEVIWLHNGNEI 594

Query: 2817 PSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +      +  SL I   + ED+G YTC+A NS G   T   L
Sbjct: 595  QESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 5/143 (3%)

Query: 2319 AINALGHCTS-AISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
            A+ A+G  +S A+   ++ + S       P   EK+   E         + E     +P 
Sbjct: 1682 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1741

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSM 2436
            F++ +++++ + EG  A FDC++    DP  +V WF++++ I +S      +D  G  S+
Sbjct: 1742 FSKTIRDLE-VVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSL 1798

Query: 2437 TISHVRDEDEGVYMCRASNLLGE 2459
             IS V  +D+  Y C+A N LGE
Sbjct: 1799 IISDVCGDDDAKYTCKAVNSLGE 1821



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 62/232 (26%), Positives = 94/232 (40%), Gaps = 28/232 (12%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   LK    ++EGQ   F  +   +      + W  NG+ I  A   ++  + G   
Sbjct: 445  PSFSSVLKDC-AVIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I     ED G YT +A NA G+   SA +TV  + S                  +S++
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----------------RKSEY 542

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            + P   +     + P+F+Q LS+   V +G  + +  ++   G+P   V W HNG  +  
Sbjct: 543  LLP---VAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQE 596

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
               F         +L I      DTG YT  A N  G   T A++ V E  D
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 54/227 (23%), Positives = 89/227 (39%), Gaps = 11/227 (4%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            + EG+ L L+ QV   +DP   I W  NGK L+      L+ +    ++ +      D G
Sbjct: 1040 VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097

Query: 2983 IYTCKAYNKRGEAFTSSTVYC----TSKDNLIERTQHPKGTEGLEKIQNLED--SLRKEP 3036
            +Y C A N  G+A  S  V       S++      +  +    L  +   E   +++K+P
Sbjct: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
              +       PP+    F +   +  G+       +  TG Q +   W    K I+ S  
Sbjct: 1158 APKTPPKAAMPPQIIQ-FPEDQKVRAGESVELFGKV--TGTQPITCTWMKFRKQIQESEH 1214

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            ++   +     L IL  +    G Y+    NK G  +  V L  VDK
Sbjct: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 44/140 (31%), Positives = 66/140 (47%), Gaps = 5/140 (3%)

Query: 4374 GDKEITRKITSTETTE-IEHKAQTQERVVEGPV--KPSKPPIFTKKMQPCRVFEHEQARF 4430
            G K  T   TS    E +E +    +  +E     KP   P F+K ++   V E   ARF
Sbjct: 1700 GRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARF 1759

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489
            + + +G P P + W++++  I+ S  FQI +       LII  V  +D A +   A N  
Sbjct: 1760 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1819

Query: 4490 GTAKCSANLVVEEKRRQGRG 4509
            G A C+A L+V E   +G G
Sbjct: 1820 GEATCTAELIV-ETMEEGEG 1838



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/155 (30%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 710  TCRAVSATGVAETKAVLH-VTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ 768
            T  AV A G   + A++  ++ R +   +   P   + ++  ED S+   +   EE+   
Sbjct: 1679 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1738

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827
            +P F + ++DL E+ EG  A F+ ++    DP   V W+KD + I  S      ++  G 
Sbjct: 1739 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             SL I  +  +D   YT +AVN LGEA  TA + V
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 67/228 (29%), Positives = 98/228 (42%), Gaps = 28/228 (12%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F + +KD  ++ EG    F  +    G    R+ WL +G+P++ + R T     G   
Sbjct: 445  PSFSSVLKD-CAVIEG--QDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAE 498

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I+     D G YTC A NA+GQ + SA +T+  KK             K +YL   + 
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKSEYLLPVAP 548

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
             SK T         P FL  L    K+++G       +V    +    V W  NG +I  
Sbjct: 549  -SKPT--------APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 596

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            +            +L I  V  ED+G YT  A N+AGE +  A +TV+
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 46/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 983  TCRAYNAIGQATTSANLTIVT-KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            T  A  AIG+ ++ A ++ ++ +K        P   EK++  ED S+       E K   
Sbjct: 1679 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1738

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGY 1100
            KP F   ++   ++VEG +A F+ ++E   D    V W+ + + I  +   Q  Y + G 
Sbjct: 1739 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPD--PEVVWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             +L I+ V  +D   YT  A N+ GEA  +A + VET
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1832



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F +  ++    +G  A+F+ K+ G P P V W +    + E   + + Y+E  G+ SL
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1798

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            +I  +   D+ +YTC A N  GEA C+
Sbjct: 1799 IISDVCGDDDAKYTCKAVNSLGEATCT 1825



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 20/239 (8%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P FI   ++  ++E    +FE RV    +P  ++ W+RNG+ + SG R+     + G  S
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  V+ ED G+Y C A N  G    + T+      ++ ++    + + +      +  
Sbjct: 91   LVIHAVHEEDRGKYTCEATN--GSGARQVTV------ELTVEGSFAKQLGQPVVSKTLG- 141

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
               ++++    T   ++    + PP+F T++  +  + E +  +F C++   G P  +V 
Sbjct: 142  --DRFSASAVETRPSIWG---ECPPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVT 193

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W     PL    R +     G   +    V  +D G Y C   N  G     A +   G
Sbjct: 194  WLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 12/238 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F   ++D+ VAE +    + ++    DP   + W  NG  ++ +  +    +    +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-------QSKASLQLESQHESALQKIQ 1822
            ++++   PED G Y C A N+ G+A  S  + V        +KA      + +S+L  + 
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 1823 QLEDSSRYQRREDVEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
              E  +  +++   +     A P  I Q     K+  G+S     ++     P +   W 
Sbjct: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG-TQP-ITCTWM 1203

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
               K +Q     +  N    + L IL    E  G YT    N LG   + + L V  K
Sbjct: 1204 KFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 3/130 (2%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +L   ED S+    +  +E     P F+  ++D+ V E  AA F+ ++    DP+  V W
Sbjct: 1716 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1773

Query: 1747 LRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             ++   I  S      +D  G  +L +  V  +D   YTC+A+N LGEA  ++ L V++ 
Sbjct: 1774 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1833

Query: 1806 ASLQLESQHE 1815
               + E + E
Sbjct: 1834 EEGEGEGEEE 1843



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 38/120 (31%), Positives = 62/120 (51%), Gaps = 5/120 (4%)

Query: 1953 EKIQYLEDDSR-YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
            EK++  ED S+ +  AV ++   V KP F K I++ EV EG     +  +    DP   V
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHV-KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EV 1771

Query: 2012 EWYCNGRPVQQGHRFKTTYDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             W+ + + +++   F+  YD  G  +L I     +D   Y CKA N++GEA  T+ + V+
Sbjct: 1772 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 55/235 (23%), Positives = 92/235 (39%), Gaps = 14/235 (5%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F + L ++   EG  + L+C++    D    + W  NGK +KT      + E    +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV------IAKKDLILESQHP-SGLEKIQ 1422
            + +    PED G+Y C A N  G+A  SC + V         K   ++S+ P S L  + 
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 1423 YLEDTSRYKKTDI--IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEW 1480
              E  +  KK           + P+ +  P+  + V  G+ V    K+       +   W
Sbjct: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKV--TGTQPITCTW 1202

Query: 1481 FKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             K  + +      +  +      L I+    E  G YT    N +G+ +    LT
Sbjct: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1257



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 8/123 (6%)

Query: 43  HFTRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPV 102
           H ++   +   S  D  P+T   P    PP      +N    +G  AKFEG++RG P P 
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEA-PAFILPP------RNLCIKEGATAKFEGRVRGYPEPQ 63

Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           V+W R   P+    ++ +    + G  SL+I  +   D G+YTC A N  G    +V + 
Sbjct: 64  VTWHRNGQPITSGGRFLLDCGIR-GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122

Query: 163 PEG 165
            EG
Sbjct: 123 VEG 125



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 61/212 (28%), Positives = 85/212 (40%), Gaps = 26/212 (12%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG     +C V     P +T  W  NGQ I+     R+T + G   L I     ED GTY
Sbjct: 458  EGQDFVLQCSVRGTPVPRIT--WLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPP 2242
             C A N LG+   +C+  V  H             +  R+ E       + V   K + P
Sbjct: 513  TCLAENALGQV--SCSAWVTVHEK-----------KSSRKSEYL-----LPVAPSKPTAP 554

Query: 2243 RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
             F+  L     V +G       QV    +P   + + HNG  +Q +  FH        SL
Sbjct: 555  IFLQGL-SDLKVMDGSQVTMTVQVSG--NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             IQ   PED G Y+ +A N+ G   +   +TV
Sbjct: 612  WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 58/243 (23%), Positives = 97/243 (39%), Gaps = 17/243 (6%)

Query: 258  RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            RS    + P   QK ++  + EG     Q Q+S +P   + W  NG+ L  + K  I++ 
Sbjct: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1079

Query: 318  HNHT-TLRVRNTQKSDSGHYTLLAENPNG-----CIVTSGYLAVESPTESYVQDQRSQYI 371
                 ++ +      D G Y  +A+N  G     C VT         T++     R    
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1139

Query: 372  TDTQQRETEERIEISEK---------ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            +      TE    + +K         A+ PQ ++  +D+ V  G+      +VTG     
Sbjct: 1140 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1199

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             TW    +QI++  + K+  +E+G+  L I        G  T +  NK G    Q  L V
Sbjct: 1200 CTWMKFRKQIQESEHMKVENSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258

Query: 483  IEK 485
            ++K
Sbjct: 1259 VDK 1261



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 63/218 (28%), Positives = 91/218 (41%), Gaps = 28/218 (12%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F + L+    V EG+    +C V     P  RI +  NG+ +Q A     T + G   
Sbjct: 445  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYARS---TCEAGVAE 498

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L IQ  +PED G Y+  A NALG  + +  +TV  K S    S++ E             
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSE------------- 541

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            +  P  P   T   P+F Q L ++  + +G       ++   G+P  +V W  N   I++
Sbjct: 542  YLLPVAPSKPT--APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 596

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S            S+ I  V  ED G Y C A N  GE
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGE 634



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 35/237 (14%)

Query: 3558 PEFTTTPSDLILSENSSAHFEC--RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            P F++   D  + E      +C  R  PV     R+ W  NG+P+      ++  + G  
Sbjct: 445  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVP----RITWLLNGQPI---QYARSTCEAGVA 497

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I      D G YTC A N  G+  VSC   V              H K  +   + L
Sbjct: 498  ELHIQDALPEDHGTYTCLAENALGQ--VSCSAWVT------------VHEKKSSRKSEYL 543

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
                     + +   KP  P F   + D + V +G  V    +V   G+P   + W HNG
Sbjct: 544  ---------LPVAPSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 591

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
                     H        +L I  ++  D G YTC A N  G   T A +T     D
Sbjct: 592  NEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 4/154 (2%)

Query: 1251 TVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            T  AV  +G   + A++  +  R        +    E+++  ED ++   +   +     
Sbjct: 1679 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1738

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD-YV 1368
             P FS+ + ++E VEG+    +C+++   D    V WF + + I+    F+  Y+ D   
Sbjct: 1739 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNC 1796

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L +  V  +D   YTC+A N LGEA  +  L V
Sbjct: 1797 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 51/226 (22%), Positives = 93/226 (41%), Gaps = 31/226 (13%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F S L +    EG +   +C+V  +  P  +I W  N +P+      +ST +     L I
Sbjct: 447  FSSVLKDCAVIEGQDFVLQCSVRGT--PVPRITWLLNGQPIQYA---RSTCEAGVAELHI 501

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                 ED G YTC A N+ G  + S  +                       V + + +R 
Sbjct: 502  QDALPEDHGTYTCLAENALGQVSCSAWV----------------------TVHEKKSSRK 539

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLE 2955
            ++   P  P    P     +   ++ ++++G  + +  QV    +P  ++ W  NG  ++
Sbjct: 540  SEYLLPVAPSK--PTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQ 595

Query: 2956 QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            +   F         +L + +V+  D+G YTC+A+N  GE  T + +
Sbjct: 596  ESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 60/244 (24%), Positives = 100/244 (40%), Gaps = 16/244 (6%)

Query: 2226 QGHSTRIEVE---EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
            +GH+   + E   E + + P F  +L+   HV EGK    +CQV    DP   I +  NG
Sbjct: 1010 RGHAGTTDNEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSS--DPPATIIWTLNG 1066

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV----TAKG 2338
            K L++     ++ +    S+ I+  +PED G Y   A N  G    +  +TV     ++ 
Sbjct: 1067 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1126

Query: 2339 SIISE--SQRPE-GLEKIRELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTA 2394
            +   E  S+RP+  L  +   ES    K+   P+ P     P           ++ G++ 
Sbjct: 1127 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1186

Query: 2395 HFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
                ++   G   +   W +  K I++S  +   +      +TI   R E  G Y     
Sbjct: 1187 ELFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1244

Query: 2455 NLLG 2458
            N LG
Sbjct: 1245 NKLG 1248



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 3/134 (2%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + +  + +G+     + E   S+    PPK A K     ++EG   +F  +++G P+P+V
Sbjct: 133 QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-- 355
           TW K    L  S +  +   +    L +    + D G YT L  N +G    S  L++  
Sbjct: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252

Query: 356 -ESPTESYVQDQRS 368
            +S   S+V++ ++
Sbjct: 253 LDSANRSFVRETKA 266



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 61/232 (26%), Positives = 91/232 (39%), Gaps = 28/232 (12%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F+  +KD   V EG      C V   G P  RI W  NG+P        +  + G   
Sbjct: 445  PSFSSVLKD-CAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPI---QYARSTCEAGVAE 498

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L I      D G YTC A N  G  + +A +T   K+            S  K + L   
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK------------SSRKSEYL--- 543

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
             +  AP +     T P F+  +    ++  +G +    V+   +P   + W  NG  +  
Sbjct: 544  -LPVAPSK----PTAPIFLQGLSD--LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
               +         SL I  V+ ED+G Y C A N  GE  T+A ++ ++  D
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 4/100 (4%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GY 966
            KP F   I+D + + EG  A F+ ++E   D    V W KD + +  S      ++  G 
Sbjct: 1739 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
             +L I  V   D   YTC+A N++G+AT +A L + T ++
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1835



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 55/224 (24%), Positives = 87/224 (38%), Gaps = 12/224 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG  +  +C V  S DP   I W  N K L +      + + S  S+ I
Sbjct: 1031 FKQKLQDVHVAEGKKLLLQCQV--SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQ-----GKAGLEAVEQA 2890
                 ED G+Y C A N  G A  S  +    D     +T+ P+      K+ L  V   
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQV-TVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147

Query: 2891 E-EARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949
            E +A + K   P  P      P+ II    + ++  G+ + L G+V       +   W  
Sbjct: 1148 ESDATVKKKPAPKTPPKAAMPPQ-IIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMK 1204

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
              K +++    K+ +      L ++   +   G YT    NK G
Sbjct: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 4/124 (3%)

Query: 2613 PESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            P + E+++ +E       E   +      P F+  ++  + +VEG     + ++E   DP
Sbjct: 1711 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1769

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
              ++ WFK+  ++      +  +D  G  +L I+ +  DD   YTCKA N LGEA  TA 
Sbjct: 1770 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1827

Query: 2732 IKIE 2735
            + +E
Sbjct: 1828 LIVE 1831



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 5/101 (4%)

Query: 3687 IEDEKPN-PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
            + +EKP+  P F+  I+D ++V EG    FDC++E   DP   + WF + +         
Sbjct: 1731 VAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQ 1787

Query: 3746 -TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               ++ G  +L I  +   D  +YTC+A N  G AT TA++
Sbjct: 1788 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1828



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 4/120 (3%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            EKL++ ED      +   EE+    P F+  + ++E + EG  A F+ ++    DP  +V
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV-EGSAARFDCKIEGYPDP--EV 1771

Query: 3455 EWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             W+ + +S++    F+  + + G   L IS    +D  +Y C+A N+ GEA  TA + V+
Sbjct: 1772 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 55/226 (24%), Positives = 90/226 (39%), Gaps = 14/226 (6%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F  +L     ++EG+    +C++    DP   + W  NGK L++      S +    
Sbjct: 1028 APAFKQKLQD-VHVAEGKKLLLQCQVSS--DPPATIIWTLNGKTLKTTKFIILSQEGSLC 1084

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-------QSKESIIRDSQHESALEKI 1955
            ++ I     ED G Y C A N+ GQA  S ++ V        +K   ++  + +S+L  +
Sbjct: 1085 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144

Query: 1956 QYLEDDSRYKR--AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW 2013
               E D+  K+  A +        PQ  +  ++ +V  G  V L   +T     T    W
Sbjct: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT--CTW 1202

Query: 2014 YCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
                + +Q+    K         L IL A  E  G Y     N +G
Sbjct: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 1/87 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYE 4785
            +RD+ V EG  A+F  +I     P + W ++   I E+  FQ+ + E  N  L+I +   
Sbjct: 1746 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1805

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +D   +TC+A  + G+   +A+L+V++
Sbjct: 1806 DDDAKYTCKAVNSLGEATCTAELIVET 1832



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 52/251 (20%), Positives = 93/251 (37%), Gaps = 10/251 (3%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E   E     P F + LQD+  + EG+    + Q++  SDP   + W  +G+ +  +  I
Sbjct: 1019 EKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFI 1075

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV----AARSTVTADLGIP 875
                     S++I     ED G Y   A N  G+A  +  + V    A+ +T   ++   
Sbjct: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935
              +  +                     P++   P+     +DQ  ++ G       ++  
Sbjct: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ-KVRAGESVELFGKVT- 1193

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             G   +   W+K  + ++ S  +    +     LTI +      G YT    N +G    
Sbjct: 1194 -GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQA 1252

Query: 996  SANLTIVTKKD 1006
              NLT+V K D
Sbjct: 1253 QVNLTVVDKPD 1263



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 5/108 (4%)

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            E  +++ +  +    +E+P V   P F   I+   V E    RF+C++E   DP+  + W
Sbjct: 1718 ESEEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1773

Query: 3866 YRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            +++ + +     ++  YD  G  SL I  V  +D  +Y C+AVN  GE
Sbjct: 1774 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1821



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 32/232 (13%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F + ++D   ++EGQ    +  +     P  ++ W  NG+ + +    R+  + G+  
Sbjct: 445  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401
            L I     E+ G Y C+A N LG+ S  A +    K++      L               
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL--------------- 543

Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461
                      V   K  AP+F   LS+++ + +G       +++    P  +V W  NG 
Sbjct: 544  --------LPVAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVSGNPPP--EVIWLHNGN 592

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             ++    F          L I   +PED+G Y C A+N+ GE  T A + VQ
Sbjct: 593  EIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 58/258 (22%), Positives = 90/258 (34%), Gaps = 10/258 (3%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G++GT D        G  P F     D+ ++E      +C++   +D    + W  NGK 
Sbjct: 1011 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKT 1068

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI--IL 3657
            L T   +    +     + I      D GLY C A N  G+A  SC++ V          
Sbjct: 1069 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1128

Query: 3658 EPQLPSHF-KSGTESIQKLEE--TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVH 3714
             P++ S   KS    +   E   T+ K+       +   PP+  ++  ++  V  G  V 
Sbjct: 1129 APEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI-IQFPEDQKVRAGESVE 1187

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
               +V   G   +   W    +       +   N      L I        G YT    N
Sbjct: 1188 LFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVEN 1245

Query: 3775 KWGSATTTAKITCSAKRD 3792
            K GS      +T   K D
Sbjct: 1246 KLGSRQAQVNLTVVDKPD 1263



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 39/109 (35%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 470 KSGETA-FQCR-LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
           K  +T  F+C  L V+E    VAP F        V EG+  VL     GTP PRITW  +
Sbjct: 426 KENQTVKFRCEGLAVME----VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 481

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           G PI      R   + G + L I  A   D   Y C A+N  G  +  A
Sbjct: 482 GQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 527



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + E+R E   +  AP F +  QD  V EGK     C+V+  P   + W +N + ++    
Sbjct: 1017 DNEKRSE--SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-K 1073

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE---KEQVVAPKFV 494
              IL  E    ++ I      D G+  CVA+N +G+    C++ V +    E   AP+  
Sbjct: 1074 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1133

Query: 495  ER 496
             R
Sbjct: 1134 SR 1135



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 57/243 (23%), Positives = 98/243 (40%), Gaps = 19/243 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L+  + + EG+    + +V   SD   T+ W  NGK + +   I    +    +
Sbjct: 1029 PAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            + I     ED G+Y  VA+N AG+A+ S  +TV+   + + +   +    K+R  + S  
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT---KAPEMKSRRPKSS-- 1140

Query: 1163 VEPMYQIEEIS--KSKPVFVQP--LSNPPPV---SEGKNIHLECRLEPMGDPT----MRV 1211
            + P+   E  +  K KP    P   + PP +    E + +     +E  G  T    +  
Sbjct: 1141 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1200

Query: 1212 EWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             W    + +      K         L I+ A     G YT+   N LGS      + V++
Sbjct: 1201 TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260

Query: 1272 RSD 1274
            + D
Sbjct: 1261 KPD 1263



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 7/137 (5%)

Query: 2201 VAGHRNIILDTQHPNGLEKIRQLE--AQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            ++G ++       P   EK+   E  +Q     +  E+P + P  + ++      V EG 
Sbjct: 1698 LSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP--YFSKTIRDLEVVEGS 1755

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSV 2317
             A F+C++E   DP   + ++ + ++++ +  F I +D  G  SL I     +D  +Y+ 
Sbjct: 1756 AARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1813

Query: 2318 KAINALGHCTSAISMTV 2334
            KA+N+LG  T    + V
Sbjct: 1814 KAVNSLGEATCTAELIV 1830



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 3/131 (2%)

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
            E+++  ED S+     + +E     P  + +++++E+ EG  A F+ ++    D   +V 
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVV 1772

Query: 1613 WYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
            W+ +++ ++    F  + +  G  +L I     +D   YTC+A+N+LGEA  +   IV +
Sbjct: 1773 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1832

Query: 1672 KKSIYLESQHE 1682
             +    E + E
Sbjct: 1833 MEEGEGEGEEE 1843



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 57/243 (23%), Positives = 89/243 (36%), Gaps = 36/243 (14%)

Query: 3031 SLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090
            SL  +P +         P F    +++  I EG  A +E  +   G     + W  NG+ 
Sbjct: 16   SLSVDPSRVDSMPLTEAPAFILPPRNLC-IKEGATAKFEGRV--RGYPEPQVTWHRNGQP 72

Query: 3091 IEASHRIRTVYAF-GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC--------- 3140
            I +  R        G   L I      D G Y+C ATN  G  +++V+L           
Sbjct: 73   ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLG 132

Query: 3141 ---VDKSKGQK-----------------PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
               V K+ G +                 P+F T +  +  +K+GQ   F C +     P 
Sbjct: 133  QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKIT--GRPQ 189

Query: 3181 MKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             ++ W     P++ S R+      G  VL+I      D G Y C   N  G+    A ++
Sbjct: 190  PQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELS 249

Query: 3241 CYG 3243
              G
Sbjct: 250  IQG 252



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           P +P+ PIF Q   + +   G       ++ GNP P V W      + E   +   + ++
Sbjct: 548 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQR 605

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
               SL I+++ P D G YTC A N  GE
Sbjct: 606 GTQHSLWIQEVFPEDTGTYTCEAWNSAGE 634



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 52/242 (21%), Positives = 89/242 (36%), Gaps = 12/242 (4%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            E +G AP F   L ++ ++ EG+    + +++   DP   + W  NGK+LK  ++F    
Sbjct: 1023 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT-TKFIILS 1078

Query: 3474 DFGFVI-LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ---GKRNIILESQLPKGME 3529
              G +  + I    PED G Y C A N+ G+A  +  + V       N        +  +
Sbjct: 1079 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1138

Query: 3530 GTIDKIAALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
             ++  +   E  +       P+   ++  PP+    P D  +    S     ++      
Sbjct: 1139 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQ 1196

Query: 3588 SMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
             +   W    K +     +K  N      L I    Q   G YT    N+ G       L
Sbjct: 1197 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256

Query: 3648 QV 3649
             V
Sbjct: 1257 TV 1258



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 56/231 (24%), Positives = 89/231 (38%), Gaps = 28/231 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P F+ VL   + + EGQ    +  V   G P  R  W +NG  ++     R+T + G   
Sbjct: 445  PSFSSVLKDCAVI-EGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L I   +  D G Y C A N  G                        +W  +  K+++  
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCS-------------------AWVTVHEKKSSRK 539

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                + V      APIF   L    K+++G  V +  QV     P  ++ W  NG  +  
Sbjct: 540  SEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQVTMTVQVSGNPPP--EVIWLHNGNEIQE 596

Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
                         +L I  +  +D+G YTC+A N  GE  + A + +++ H
Sbjct: 597  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 647



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIK 4749
            GD K VA +   + +++              PA + P R++ + EG  A+F+ ++    +
Sbjct: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            P + W R G  I     F ++  G      L+I   +EED G +TC AT  +G  + + +
Sbjct: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 4808 LVVK 4811
            L V+
Sbjct: 121  LTVE 124



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 5/90 (5%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F  + K+    +G +   +  +RG P P ++W     P+    +Y+ R   + G   L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYA-RSTCEAGVAEL 499

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            I+   P D G YTC A N  G+  CS ++
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWV 529



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F+  L  +  M+G ++    ++   G+P  ++ WL NG  I+ S  F    R    SL
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +  +  +D+G YTC A ++ G   T+AVL V
Sbjct: 612 WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 630  EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            E++ +  P F   ++ +  +EG    F+ +IE   DP  ++ W K+ QSI  S  F   +
Sbjct: 1733 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDY 1790

Query: 690  -RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
               G  SL +  +   D  +YTC+AV++ G A   A L V
Sbjct: 1791 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 57/237 (24%), Positives = 91/237 (38%), Gaps = 33/237 (13%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F   L+D   + EG++  F  Q +    P  R+ W  +G+PI  +    S    G   
Sbjct: 445  PSFSSVLKDCAVI-EGQD--FVLQCSVRGTPVPRITWLLNGQPIQYAR---STCEAGVAE 498

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L+I     ED G+YT  A N LG+   +A + V  + +         +  Y+        
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-------SRKSEYLLPVA---- 547

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                         P     P F   + D + + +G       ++   G+    V WL +G
Sbjct: 548  -------------PSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 591

Query: 950  RPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
              ++ S            +L I+ V   D G YTC A+N+ G+  T A LT+    D
Sbjct: 592  NEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 27/226 (11%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F   LK    +EG     +  +   G P  +I WL NGQ I+ +    S    G   L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 499

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
            +     +D G YTC A +A G     A + V  + +  +                 S+Y
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK-----------------SEY 542

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
               +  + T+  P F++ L DL ++ +G       Q++   +P   V W  +G  I  S
Sbjct: 543 LLPVAPSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 597

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                       SL I  +  ED G+YT  A N  GE  + A + V
Sbjct: 598 EDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 55/225 (24%), Positives = 97/225 (43%), Gaps = 29/225 (12%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            P F++ +++   + +GQ    +C+V     P  +I W  NGQP++++   ++  + G   
Sbjct: 445  PSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 498

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQG 3268
            L I      D G Y C A N  G+    A +  + K      S + + L  +        
Sbjct: 499  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSEYLLPV-------- 546

Query: 3269 AQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG 3328
                 PS P+A  P F+  + D+ K+++G       ++    +P  +V W +NG ++   
Sbjct: 547  ----APSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 597

Query: 3329 HRYRTFHDFGIV-ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              +  F   G    L I   + E++G Y C A N  G   T+A L
Sbjct: 598  EDFH-FEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 19/282 (6%)

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQ 1979
            + +  +G A     L   SKE + +D +++   ++      D+  +   Q  +     P 
Sbjct: 976  ETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTA-----PA 1030

Query: 1980 FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDI 2039
            F + +++  V EG  + L+  ++  +DP   + W  NG+ ++       + +    ++ I
Sbjct: 1031 FKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088

Query: 2040 LYAYAEDTGTYMCKATNAVGEAVTTSSVKVD---AKSGLYLDTLDEQRLKKI------QE 2090
              A  ED G Y C A N  G+A  +  V VD   A        +  +R K         E
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148

Query: 2091 LEKYERPKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
             +   + KP  +  P    P  +      + ++ G+      +V       +T  W    
Sbjct: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMKFR 1206

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            ++I+     +  +      L IL    E  G Y     NKLG
Sbjct: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F   L+    + EG+ + L+ QV   +DP   I W  NG TL T   +  + +  L 
Sbjct: 1028 APAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1084

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            ++SI     +D G+Y C A N  G+A  +  + ++D
Sbjct: 1085 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1120



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 11/154 (7%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT-TDSGTYSCRATNKWGQAEISVK-LEC 3140
            +W   G  + A  R+ ++     ++  + G K+ T S T    A     + ++S   LE 
Sbjct: 1675 KWQKTGNAVRAIGRLSSM----AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1730

Query: 3141 VDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199
            V + K   KP F+  I+++E + +G +A F+C +    DP+  + W+ + Q +R S   +
Sbjct: 1731 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQ 1787

Query: 3200 -TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                + G   L I+     D  +Y C+A N  GE
Sbjct: 1788 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1821



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP F+  L +   + EG++   +  +  T  P  ++ W  NG+ ++     R+ C+ G  
Sbjct: 444  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 497

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQL----PKGMEGTI-- 3532
             L I    PED G Y C A N  G+   +A + V  K++      L    P      I  
Sbjct: 498  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 557

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECR 3580
              ++ L+   G+  T+T +     PPE     +   + E+   HFE R
Sbjct: 558  QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 16/245 (6%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            +S+G  P F   +Q++  + +G+    +C V    DP   I W  NG+ ++ +  I    
Sbjct: 1023 ESQGTAPAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1079

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATIN----CYGKGGVYLESLQP-D 3255
            +     + I      D G Y C A N  G  E   + T++            ++S +P  
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1139

Query: 3256 SLAKIRELESLQGAQQQ-TPSTP--SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDP 3312
            SL  +   ES    +++  P TP  +A PP+ I Q  +  K+  G+S     ++      
Sbjct: 1140 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQII-QFPEDQKVRAGESVELFGKVTGTQ-- 1196

Query: 3313 DLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +   W    K++      +  +      L IL   +E+ G Y  +  NKLG    + NL
Sbjct: 1197 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256

Query: 3373 KCTSK 3377
                K
Sbjct: 1257 TVVDK 1261



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 42/151 (27%), Positives = 69/151 (45%), Gaps = 9/151 (5%)

Query: 1127 AQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNP 1186
            A +S     ++ +   TS ++    E    + ++ F+E +   EE    KP F + + + 
Sbjct: 1693 AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQA-FLEAV--AEEKPHVKPYFSKTIRDL 1749

Query: 1187 PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFVALDIIHATSA 1245
              V EG     +C++E   DP   V WF + +S+     F+  YD  G  +L I      
Sbjct: 1750 EVV-EGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1806

Query: 1246 DTGEYTVRAVNHLGSAHTSA--IVRVIERSD 1274
            D  +YT +AVN LG A  +A  IV  +E  +
Sbjct: 1807 DDAKYTCKAVNSLGEATCTAELIVETMEEGE 1837



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 4078 PKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGH 4137
            P    + EK+   E   Q   E V EE K    P F      + V EG  ARF C++ G+
Sbjct: 1708 PTSPLNAEKLESEEDVSQAFLEAVAEE-KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1766

Query: 4138 PKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P P V+W  +  +I     +++ YD
Sbjct: 1767 PDPEVVWFKDDQSIRESRHFQIDYD 1791



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT--YDGMYHFD 4168
            P F+  P  + ++EG  A+F  RV G+P+P+V W  NG  I +G R+ L     G +   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4169 IPKTRQYDTGK 4179
            I    + D GK
Sbjct: 93   IHAVHEEDRGK 103



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 40/129 (31%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 44  FTRQMTTQVESS--GDRQPITA--GRP---GEPSPPIFEQIFKNARFAQGGNAKFEGKLR 96
           F +Q+   V S   GDR   +A   RP   GE  PP F          +G   +F  K+ 
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE-CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P V+W +   PL    + S+  +E+ G   L I  +   D G YTC   N  G+A 
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSV--SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243

Query: 157 CSVYIQPEG 165
            S  +  +G
Sbjct: 244 MSAELSIQG 252



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 37/239 (15%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            ++   P F + +K   V E +    +C V  +  P  RI W  NG+ +      R+  + 
Sbjct: 440  VMEVAPSFSSVLKDCAVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 494

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            G   L I     ED G Y C A N  G+      +SC     +       +  ++SE L 
Sbjct: 495  GVAELHIQDALPEDHGTYTCLAENALGQ------VSCSAWVTV----HEKKSSRKSEYL- 543

Query: 3945 QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPN 4004
             +     K T+ ++L                    Q  + L  M+ ++    +   G+P 
Sbjct: 544  -LPVAPSKPTAPIFL--------------------QGLSDLKVMDGSQVTMTVQVSGNPP 582

Query: 4005 MKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
             +V W  NG  +     F         ++    V+PED+G Y C A N  G   T+AV+
Sbjct: 583  PEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 641



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 54/241 (22%), Positives = 84/241 (34%), Gaps = 15/241 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  +++D + V EG  +   C+V    DP   I W  NG+   T   +    +    +
Sbjct: 1029 PAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER- 3813
            + I+     D G Y C A N  G A  + ++T          ++ P+  S      L   
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD-DAPASENTKAPEMKSRRPKSSLPPV 1144

Query: 3814 -GRISDA-------PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
             G  SDA       PK  P  + PP+ I   +   V   E V    +V   +   +   W
Sbjct: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQ--PITCTW 1202

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             +  K +      +         L IL    E  G Y     N  G    +  ++    P
Sbjct: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262

Query: 3926 D 3926
            D
Sbjct: 1263 D 1263



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD-FSYVSLD 2834
            F   + ++   EG    F+C +E   DP  ++ WF +++ +     ++  +D     SL 
Sbjct: 1742 FSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I+    +D   YTCKA NS G AT +  L
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1828



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/86 (25%), Positives = 41/86 (47%)

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            + Q  AP F ++   ++V EG+ ++L  +    P   I W  +G  +     + +  +G 
Sbjct: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1082

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
              ++ I +A   D   Y+C A+N AG
Sbjct: 1083 LCSVSIEKALPEDRGLYKCVAKNDAG 1108



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592
            +K+ + E  S        E +    P F+ T  DL + E S+A F+C++    D    V 
Sbjct: 1715 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VV 1772

Query: 3593 WFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            WF + + +      +   ++ G   L I  V   D   YTCKA N  GEAT + +L V+
Sbjct: 1773 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 56/240 (23%), Positives = 92/240 (38%), Gaps = 17/240 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP     L++V + EG++   + ++   SD    + W  N K LK+      +      +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV------HSKKSIYLESQH-EGALPRLN 1689
            + I   LPED G Y C A N  G+A  S    V       + K+  ++S+  + +LP + 
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ--AAHFEARLI--PVGDPKLRVE 1745
              E  +  ++  A        P   MP + I+  E+Q   A     L     G   +   
Sbjct: 1146 GTESDATVKKKPAP----KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W++    I+ S  +   +      L +     E  G YT    N+LG       L V  K
Sbjct: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            E  G  P F   L  + ++ EG +   +C+V   +DP  TI W  NG+ ++       + 
Sbjct: 1023 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1079

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +    ++ I     ED G Y C A N  G+A  +C + V
Sbjct: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 1/100 (1%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNH 320
            P   P  ++  R+ ++ EG+ A+F  ++ G P P V WFK+ Q +  S   +I      +
Sbjct: 1736 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             +L + +    D   YT  A N  G    +  L VE+  E
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1835



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 2/111 (1%)

Query: 470  KSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            +S E   Q  L  + +E+  V P F +    L V EG     + +  G P P + W KD 
Sbjct: 1718 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1777

Query: 529  VPIIPNPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              I  +   +I + + G  +L I      D A Y C A N  G     A L
Sbjct: 1778 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1828



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++ ++ EG+     C++    DP   + W  N K ++ +  I  + +    S
Sbjct: 1029 PAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1085

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            ++I     ED G+Y C A N  G+
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQ 1109



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNKYS 119
           +T   P + + P F    ++   + G +      + G+P P V W R  KA   +   + 
Sbjct: 641 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 700

Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSV 159
           +  NE     +L++K++ P   G+Y    +N+ GE  C V
Sbjct: 701 VLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQV 738



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 43/192 (22%), Positives = 68/192 (35%), Gaps = 10/192 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            T+++     +   P F  ++Q    + E +    +CQ++   DP   + W  NGK L   
Sbjct: 1016 TDNEKRSESQGTAPAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTT 1072

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV------Y 4073
                   +    +++     PED G Y C A N  G  E    +     P          
Sbjct: 1073 KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEM 1132

Query: 4074 DSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCR 4133
             S+ PK         E +A+ +  P       KA  PP  +  P+   V  GE      +
Sbjct: 1133 KSRRPKSSLPPVLGTESDATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVRAGESVELFGK 1191

Query: 4134 VTGHPKPRVMWL 4145
            VTG       W+
Sbjct: 1192 VTGTQPITCTWM 1203



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+Q  ++   A+G     + ++  +P   + WT     L +  K+ +  +++    S+
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFII-LSQEGSLCSV 1086

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             I++  P D G Y C A+N  G+A CS  +
Sbjct: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQV 1116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERD 2980
            ++VEG     + ++E   DP+  + W+ + + + +   F++  D  G  +L + DV   D
Sbjct: 1750 EVVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1807

Query: 2981 SGIYTCKAYNKRGEA 2995
               YTCKA N  GEA
Sbjct: 1808 DAKYTCKAVNSLGEA 1822



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            +D  K      T P F  +++   V E + +  +C+V    DP   I W  NGK L +  
Sbjct: 1016 TDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTK 1073

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
                  +    S+ I     ED G Y C A ND G+
Sbjct: 1074 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1109



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/92 (22%), Positives = 41/92 (44%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F +K+Q   V E ++   + +   +P   I W      +K +    +    +   + I
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
             +   ED  ++  VA+N  G A+CS  + V++
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1120



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 3013 TQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASL 3072
            T  P      EK+++ ED  +       ++     P F+   +D+ ++ EG  A ++  +
Sbjct: 1705 TGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKI 1763

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
                D  +V  WF + ++I  S   +  Y   G   L I      D   Y+C+A N  G+
Sbjct: 1764 EGYPDPEVV--WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1821

Query: 3132 AEISVKL--ECVDKSKGQ 3147
            A  + +L  E +++ +G+
Sbjct: 1822 ATCTAELIVETMEEGEGE 1839



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 14/127 (11%)

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPK----FITQIQDVTKLVEGQSAHFEARLVPV 3309
            P S     +LES +   Q      + E P     F   I+D+ ++VEG +A F+ ++   
Sbjct: 1708 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGY 1766

Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHD----FGIVILDILYCYEENSGEYECVATNKLGR 3365
             DP+  V WF + + +     ++  +D      ++I D+  C ++++ +Y C A N LG 
Sbjct: 1767 PDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV--CGDDDA-KYTCKAVNSLGE 1821

Query: 3366 DSTKANL 3372
             +  A L
Sbjct: 1822 ATCTAEL 1828



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GF 2565
            KP F++ +    E+ EG  A ++ ++    DP +   W+ +   ++    F+  +D  G 
Sbjct: 1739 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEV--VWFKDDQSIRESRHFQIDYDEDGN 1795

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I+ V  +D   Y CKA+N  G
Sbjct: 1796 CSLIISDVCGDDDAKYTCKAVNSLG 1820



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 2232 IEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL-QSAA 2289
            + V+EP   + P F+++ R  T    G++    C +    DP   + +  +GKAL +   
Sbjct: 641  LTVQEPHDGTQPWFISKPRSVTASL-GQSVLISCAI--AGDPFPTVHWLRDGKALCKDTG 697

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS-MTVTAKGSIISESQRPE 2348
             F +  +    +L ++   P  AG+Y +   N +G C+  +S M   +    +   + P 
Sbjct: 698  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 757

Query: 2349 GLEKI 2353
              E +
Sbjct: 758  SCEDL 762



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 13/120 (10%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL--PSGHRYR 3879
            +EP   T P FI++ +S T    + V   C +    DP   + W R+GK L   +GH + 
Sbjct: 644  QEPHDGTQPWFISKPRSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGH-FE 700

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
             + +    +L +  V    +G+Y     N  GE        C     ++LQN   R + R
Sbjct: 701  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--------CSCQVSLMLQNSSARALPR 752



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 33/88 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P+ ++      VR GE V L  +  GT     TW K    I  +  +++      S L I
Sbjct: 1169 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1228

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A+      Y    +N  GS   +  L
Sbjct: 1229 LAARQEHCGCYTLLVENKLGSRQAQVNL 1256



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 1738 GDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            GDP   V WLR+G  + + +     + +     L +K V P  +G Y     N +GE   
Sbjct: 677  GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 736

Query: 1797 SSTLFVQSKASLQLESQHESA 1817
              +L +Q+ ++  L    E A
Sbjct: 737  QVSLMLQNSSARALPRGREPA 757



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
            +E+RSE    +   P F Q L     + EG+    + +V    DP     W +NG  LK 
Sbjct: 1018 NEKRSES---QGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT 1071

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                  + +    ++ I   +  D GLY C A N AG
Sbjct: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAG 1108


>AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform
            protein.
          Length = 2154

 Score =  171 bits (417), Expect = 4e-41
 Identities = 105/326 (32%), Positives = 157/326 (48%), Gaps = 29/326 (8%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP      Q V V SG+  R    ++G     + W K  + +    + K L +   YTLL
Sbjct: 794  PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 853

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            ++EA+P+D+  Y C A N  G A   A   V +P   +   P  +    PP II PL+D 
Sbjct: 854  LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP---EVVSPDQEMPVYPPAIITPLQDT 910

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            + +EGQ   F C++ G  L  V WY  DK IKPS++F+M++  D Y L I+EA+PEDEG 
Sbjct: 911  VTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 969

Query: 4693 YKCVAYNSAGRVTVAAKLKVT----------------------QPDQADNLPA-LTPLRD 4729
            Y  VA N+ G+V+  A L +                       + +     P+ + PL  
Sbjct: 970  YTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSS 1029

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD--FQMIHEGNNAVLLIGNTYEED 4787
            + V+ G+  +F  +++   KP IQW     LI  T D  F        A++LI + Y E 
Sbjct: 1030 LRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEH 1089

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
             G ++C+A  +AG+   +A L V  K
Sbjct: 1090 AGQYSCKAANSAGEATCAATLTVTPK 1115



 Score =  160 bits (388), Expect = 1e-37
 Identities = 171/662 (25%), Positives = 279/662 (42%), Gaps = 91/662 (13%)

Query: 1831 QRREDVEVAVN--QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
            + R  V + VN  + P+ + +L  P  +  G+ A +   I   P P  ++ WY   ++L 
Sbjct: 780  RNRSSVTLYVNAPEPPQVLQELQ-PVTVQSGKPARFCAVISGRPQP--KISWYKEEQLLS 836

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
            +G + +  +D     L ++  + ED+  YTC+A N+ G A +S  L+V+  E +      
Sbjct: 837  TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVS----- 891

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008
                                 D    V  P    P+++   +EG P   +     V+   
Sbjct: 892  --------------------PDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTD 928

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            ++V WY   + ++    F+ T       L+I  AY ED GTY   A+NAVG+  +T+++ 
Sbjct: 929  LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 988

Query: 2069 VDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAH 2128
            ++  S    +T + Q    +    K E   P+     GQ+P F+  L+SL  +  G+   
Sbjct: 989  LEGFSKFEENTSNSQWHVSLSVSFKKE---PL-----GQKPSFIQPLSSL-RVHNGETVR 1039

Query: 2129 FECRVEPINDPHLTIDWFHNGQKIRAGHR--YRTTHDFGYVALDILYTYAEDSGTYMCKA 2186
            F  RV  I  P   I WFHN Q I       +      G   + I+  Y+E +G Y CKA
Sbjct: 1040 FHARVSGIPKPE--IQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKA 1097

Query: 2187 TNKLGEAVNTCTLKVAG-------HRNI--ILDTQHPNGLEKIRQLEAQG-HSTRIE--- 2233
             N  GEA    TL V         H  I   ++ +           E +G HS  ++   
Sbjct: 1098 ANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 1157

Query: 2234 -------VEEPKISPPRFVTELRGTTHVFEGKTAHFE--------CQVEPVHDPNLRIEF 2278
                   + E  +   +F +E  GT  +F  + ++ +          V  +  P  +I++
Sbjct: 1158 INETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQW 1217

Query: 2279 YHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKG 2338
            + NG  L  +A +   FD    SL I     ED GEY+  A N  G    +  + + +KG
Sbjct: 1218 FFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG 1277

Query: 2339 SIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDC 2398
                     EG  K  E ESA      ++  P     P F + L+ I    +G  A F+ 
Sbjct: 1278 ---------EG-HKDTETESAVAKSLEKLGGPCP---PHFLKELKPI-RCAQGLPAIFEY 1323

Query: 2399 RLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD-FGYVSMTISHVRDEDEGVYMCRASNLL 2457
             +  VG+P   V WF+  K +  S   T  H+  G  +  ++  + ED G+Y+C+A N+L
Sbjct: 1324 TV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENML 1381

Query: 2458 GE 2459
            GE
Sbjct: 1382 GE 1383



 Score =  153 bits (371), Expect = 2e-35
 Identities = 170/633 (26%), Positives = 259/633 (40%), Gaps = 105/633 (16%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            K+ W+K  Q ++ G + + +HD     L +I+   ED+ +YTC A N  G    S  L+ 
Sbjct: 825  KISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 884

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
                ++V   Q                        E+    P   T L++    EGQ A 
Sbjct: 885  E-VPEVVSPDQ------------------------EMPVYPPAIITPLQDTVTSEGQPAR 919

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656
            F+ R   VS   LKV WY  +K +K    F  T       L+I    PED GTYT  A N
Sbjct: 920  FQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASN 976

Query: 1657 ALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRH-----SAQDEVITQAP 1711
            A+G+        V S  ++ LE   +         E+TS  Q H     S + E + Q P
Sbjct: 977  AVGQ--------VSSTANLSLEGFSKFE-------ENTSNSQWHVSLSVSFKKEPLGQKP 1021

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYVA 1769
             F  P+  +RV   +   F AR+   G PK  ++W  N   I  +  +    +   G   
Sbjct: 1022 SFIQPLSSLRVHNGETVRFHARV--SGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMAL 1079

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA----------------------- 1806
            + +     E +G Y+C+A N  GEA  ++TL V  KA                       
Sbjct: 1080 MLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSS 1139

Query: 1807 --SLQLESQHESALQ--KIQQ----LEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE 1858
              S + E  H + LQ  KI +    L +S  Y  + D E      P FI +++    +S 
Sbjct: 1140 FLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSE-KEGTGPIFIKEVSN-ADISM 1197

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G  A     +   P P  +++W+FNG +L     Y+   D    +L IL    ED GEYT
Sbjct: 1198 GDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYT 1255

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK-IQYLEDDSRYKRAVQDDSFVVEK 1977
            C A N+ G+ + S  L + SK    +D++ ESA+ K ++ L                   
Sbjct: 1256 CMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC--------------P 1301

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD-FGYVA 2036
            P F K +K     +G P   E T+  V +P   V W+   + +     +   ++  G   
Sbjct: 1302 PHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGT 1359

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              +     ED+G Y+CKA N +GE+   + + V
Sbjct: 1360 FIVNDPQREDSGLYICKAENMLGESTCAAELLV 1392



 Score =  151 bits (366), Expect = 6e-35
 Identities = 168/671 (25%), Positives = 276/671 (41%), Gaps = 96/671 (14%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + P     L+ V ++ G+ A F    +       K+ WY   + L +G +    ++    
Sbjct: 793  EPPQVLQELQPVTVQSGKPARF--CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 850

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTS 1695
             L ++   PED+  YTC A N  G A TS    V   + +                    
Sbjct: 851  TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVV-------------------- 890

Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
                 S   E+    P    P++D   +E Q A F+ R   V    L+V W      I+ 
Sbjct: 891  -----SPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 942

Query: 1756 SN--RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ 1813
            S   R+T   D   + +   Y  PED GTYT  A N +G+  +++ L      SL+  S+
Sbjct: 943  SRFFRMTQFEDTYQLEIAEAY--PEDEGTYTFVASNAVGQVSSTANL------SLEGFSK 994

Query: 1814 HESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPD 1873
             E      Q     S   ++E +     Q P FI  L+   ++  G++  +  R+   P 
Sbjct: 995  FEENTSNSQWHVSLSVSFKKEPL----GQKPSFIQPLSS-LRVHNGETVRFHARVSGIPK 1049

Query: 1874 PNMRVEWYFNGKVLQSGHR--YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
            P   ++W+ N +++       +      G A + I+  Y E +G+Y+CKA N+ G+A  +
Sbjct: 1050 PE--IQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCA 1107

Query: 1932 IRLNVQSK--ESIIRDS-QHESALEKIQY------LEDDSRYKRAVQ------------- 1969
              L V  K  ESI+ +  + E  +E  ++       E++  +   +Q             
Sbjct: 1108 ATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSE 1167

Query: 1970 ----DDSFVVEK----PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021
                   F  EK    P F K + NA+++ G    L  T+  +  P  +++W+ NG  + 
Sbjct: 1168 SPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLT 1225

Query: 2022 QGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLD 2081
                +K  +D    +L IL+   ED G Y C A+N  G+ + ++ +K+++K   + DT  
Sbjct: 1226 PSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTET 1285

Query: 2082 EQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHL 2141
            E  + K   LEK   P P         P FL  L  +    +G  A FE  V  + +P  
Sbjct: 1286 ESAVAK--SLEKLGGPCP---------PHFLKELKPI-RCAQGLPAIFEYTV--VGEPAP 1331

Query: 2142 TIDWFHNGQKIRAGHRYRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
            T+ WF   +++     Y   H+  G     +     EDSG Y+CKA N LGE+     L 
Sbjct: 1332 TVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 1391

Query: 2201 VAGHRNIILDT 2211
            V      + DT
Sbjct: 1392 VLLEDTDMTDT 1402



 Score =  143 bits (347), Expect = 1e-32
 Identities = 109/405 (26%), Positives = 174/405 (42%), Gaps = 22/405 (5%)

Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITS----T 4385
            +EV     Q+ V +     D  ++  +   + +  Q Q + + V ++ I R   S    +
Sbjct: 710  KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 769

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445
            +  E    A      V   V   +PP   +++QP  V   + ARF     G P P I WY
Sbjct: 770  DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 829

Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR- 4504
            +E   +      +      +  L++ + F ED+AV+   A+N  G A  SA+L VE    
Sbjct: 830  KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 889

Query: 4505 --RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                    + PP+     Q+   + GQ  R   +V+GT  + V W    KK++P    ++
Sbjct: 890  VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRM 948

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT------ 4616
             + + TY L I EAYP+D G Y  VA N+ G+    A   +   +  ++    +      
Sbjct: 949  TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSL 1008

Query: 4617 ------KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK--Y 4668
                  +     P  I+PL    V  G+ + F  ++ G P P +QW+   +LI P+K   
Sbjct: 1009 SVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVV 1068

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            F    +     + I +A+ E  G Y C A NSAG  T AA L VT
Sbjct: 1069 FHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVT 1113



 Score =  142 bits (344), Expect = 3e-32
 Identities = 170/651 (26%), Positives = 256/651 (39%), Gaps = 97/651 (14%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E PQ  + ++   V  G P    A ++    P  ++ WY   + +  G + K  +D    
Sbjct: 793  EPPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 850

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L ++ A+ ED   Y C+A N  G A T++S+ V                    E+ +  
Sbjct: 851  TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------------------EVPEVV 890

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
             P   ++E P   P  +T L       EG  A F+CRV   +   L + W+   +KI+  
Sbjct: 891  SP---DQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPS 943

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN 2215
              +R T       L+I   Y ED GTY   A+N +G+  +T  L + G      +T +  
Sbjct: 944  RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSN-- 1001

Query: 2216 GLEKIRQLEAQGH-STRIEVE-EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPN 2273
                     +Q H S  +  + EP    P F+  L  +  V  G+T  F  +V  +  P 
Sbjct: 1002 ---------SQWHVSLSVSFKKEPLGQKPSFIQPL-SSLRVHNGETVRFHARVSGIPKPE 1051

Query: 2274 LRIEFYHNGKALQSAAR--FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS 2331
              I+++HN + +       FH     G   + I     E AG+YS KA N+ G  T A +
Sbjct: 1052 --IQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAAT 1109

Query: 2332 MTVTAKG--SIISE------------------SQRPEGLE-------KIRE---LESAEP 2361
            +TVT K   SI+ E                  S   EGL        KI E   L S  P
Sbjct: 1110 LTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESP 1169

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
                +         P+F + + N D I  G  A     +I  G P  K++WF N  L+  
Sbjct: 1170 VYSTKFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTVI--GIPKPKIQWFFNGVLLTP 1226

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHP 2481
            S+      D    S+ I   + EDEG Y C ASN  G+                 +T+  
Sbjct: 1227 SADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 1286

Query: 2482 EGM-KKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSL 2540
              + K ++KL  P              P F + L  P    +G  A +E  V  VG+P+ 
Sbjct: 1287 SAVAKSLEKLGGPC------------PPHFLKELK-PIRCAQGLPAIFEYTV--VGEPAP 1331

Query: 2541 RFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
               W+    +L     +   H+  G  T  +N     D+GLY+CKA N  G
Sbjct: 1332 TVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG 1382



 Score =  140 bits (339), Expect = 1e-31
 Identities = 205/923 (22%), Positives = 359/923 (38%), Gaps = 124/923 (13%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            ++ +W  NG +I S ++ Q        +L+I +V   D+  YT VA  A   A L     
Sbjct: 553  ISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEAR 612

Query: 1135 -VETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGK 1193
             +E R  I    +     EK R + E +  EP   ++ +   + +    +++   + + K
Sbjct: 613  HIEFRKHIKDIKV----LEKKRAMFECEVSEPDITVQWMKDDQEL---QITDRIKIQKEK 665

Query: 1194 NIHL----ECRLEPMGDPTM-------RVEWFHNGRSVTVGSRFKTYYDFGFVALDI--- 1239
             +H       R+   G  T+         + F  GR V + S  K           +   
Sbjct: 666  YVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFE 725

Query: 1240 IHATSADTGEYT--VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARR 1297
            ++    D   Y   +     +   H   + R I R   +++T+   A E   +   A R 
Sbjct: 726  VNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM-FISETRQSDAGEYTFV---AGRN 781

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
               V   +   + PQ  + L  +    G      C +   G    ++ W+   + + TG 
Sbjct: 782  RSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGF 839

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSG 1417
            + +  ++     L L+  +PED+ VYTC+A N  G A TS +L V   + +  + + P  
Sbjct: 840  KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP-- 897

Query: 1418 LEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK 1477
                                    + P  +  P       EGQ   F+C+   V+ ++LK
Sbjct: 898  ------------------------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLK 930

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            V W+   + +     FR         L+I +   ED G YT  A N VG    +  L+  
Sbjct: 931  VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 990

Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHF 1597
              +    +T N      + V              E   Q P     L ++ +  G+   F
Sbjct: 991  GFSKFEENTSNSQWHVSLSV----------SFKKEPLGQKPSFIQPLSSLRVHNGETVRF 1040

Query: 1598 ERRLIPVSDATLKVEWYHNNK---PLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
              R+  +     +++W+HN +   P K    F    + G   + I+    E +G Y+C+A
Sbjct: 1041 HARVSGIPKP--EIQWFHNQQLILPTKD-VVFHFEESTGMALMLIVDAYSEHAGQYSCKA 1097

Query: 1655 INALGEAVTSGI---------AIVHSK------------KSIYLESQHEG------ALPR 1687
             N+ GEA  +           +I+H +             S +L ++ EG       L +
Sbjct: 1098 ANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 1157

Query: 1688 LNQ-LEDTSKYQRHSAQ--DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRV 1744
            +N+ LE  S+   +S +   E     P+F   + +  ++    A     +I  G PK ++
Sbjct: 1158 INETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVI--GIPKPKI 1215

Query: 1745 EWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
            +W  NGV +  S     + D    +L + +   ED G YTC A N+ G+ + S+ L + S
Sbjct: 1216 QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 1275

Query: 1805 KASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHY 1864
            K     +++ ESA+ K   LE           ++     P F+ +L  P + ++G  A +
Sbjct: 1276 KGEGHKDTETESAVAK--SLE-----------KLGGPCPPHFLKELK-PIRCAQGLPAIF 1321

Query: 1865 ECRIEPYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAIN 1923
            E  +   P P   V W+   K L +   Y    N  G     +     EDSG Y CKA N
Sbjct: 1322 EYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAEN 1379

Query: 1924 NLGQAVSSIRLNVQSKESIIRDS 1946
             LG++  +  L V  +++ + D+
Sbjct: 1380 MLGESTCAAELLVLLEDTDMTDT 1402



 Score =  137 bits (331), Expect = 1e-30
 Identities = 157/649 (24%), Positives = 251/649 (38%), Gaps = 83/649 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP++ Q+ +   +Q G  A+F   +SG P+P+++W+K  Q L    K + +      TL 
Sbjct: 794  PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 853

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +      D+  YT  A+N  G   TS  L+VE P E    DQ                  
Sbjct: 854  LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP-EVVSPDQEM---------------- 896

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P  +   QD   +EG+  RF CRV+G    +V+W+  D++I+     ++   E
Sbjct: 897  ---PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFE 952

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV---------------------- 482
               + L I      D G  T VA N  G+ +    L++                      
Sbjct: 953  D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVS 1011

Query: 483  IEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             +KE +   P F++  S+L V  GE V  +AR  G P P I W  +   I+P  ++  H 
Sbjct: 1012 FKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHF 1071

Query: 542  D--GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPT 599
            +   G + + I  A +  A  Y C A N AG     A L            +R+      
Sbjct: 1072 EESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEM 1131

Query: 600  KVXXXXXXXXXXXXYLRH---------------VERARPYIPPGEEDRVYPPPQFIVPLK 644
            ++               H               +  +  Y    + ++    P FI  + 
Sbjct: 1132 EMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVS 1191

Query: 645  SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704
            +     G        +  +G P  KI+W  NG  +  S+ +  +F     SL +L   ++
Sbjct: 1192 NADISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLE 1249

Query: 705  DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEE 764
            D GEYTC A +  G     A L +  +        H +T       E  S     +S+E+
Sbjct: 1250 DEGEYTCMASNDYGKTICSAYLKINSKG-----EGHKDT-------ETESAV--AKSLEK 1295

Query: 765  QTSQ-RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
                  P F++ L+ +    +G  A FE   T V +P   V W+K+ + +  S   T I 
Sbjct: 1296 LGGPCPPHFLKELKPI-RCAQGLPAIFE--YTVVGEPAPTVTWFKENKQLCTSVYYTIIH 1352

Query: 824  N-FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTAD 871
            N  G  +  +   + ED+G Y  +A N LGE+   A + V    T   D
Sbjct: 1353 NPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTD 1401



 Score =  136 bits (329), Expect = 2e-30
 Identities = 116/406 (28%), Positives = 183/406 (45%), Gaps = 44/406 (10%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F K ++  +V E ++A FE E   EP   ++W +++  ++ +   +I        L+I  
Sbjct: 616  FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPS 674

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              + D+  +  VA     TAK    L VE +  + R            + V V   Q   
Sbjct: 675  TRMSDAGKYTVVAGGNVSTAK----LFVEGRDVRIRS---------IKKEVQVIEKQRAV 721

Query: 4533 LDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            ++ +V     +D +W K+G ++  Q   R+K + E   + + I E    D+G+Y  VA  
Sbjct: 722  VEFEVN-EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA-- 778

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
              G  R      V+ P               PP++++ L+   V  G+   F   I G+P
Sbjct: 779  --GRNRSSVTLYVNAPE--------------PPQVLQELQPVTVQSGKPARFCAVISGRP 822

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P + WYK ++L+      +      EYTL + EAFPED   Y C A N  G  T +A L
Sbjct: 823  QPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASL 882

Query: 4711 -----KVTQPDQADNL--PA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                 +V  PDQ   +  PA +TPL+D V  EGQPA+F+ ++ S     + W  +   I 
Sbjct: 883  SVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIK 941

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +  F+M    +   L I   Y ED GT+T  A+ A GQV ++A L
Sbjct: 942  PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 987



 Score =  129 bits (312), Expect = 2e-28
 Identities = 157/620 (25%), Positives = 250/620 (40%), Gaps = 103/620 (16%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI W+K    L+TG + K   D    TL +     +D+ +YTC+A N  G A ++AS
Sbjct: 822  PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 881

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            + +E     + E + PD    +                       I+ L + V  EG   
Sbjct: 882  LSVE-----VPEVVSPDQEMPV------------------YPPAIITPLQDTVTSEGQPA 918

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851
             F+C V  +    LK+ W+  +K +     ++ T       L+I   Y ED G YT  A+
Sbjct: 919  RFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVAS 975

Query: 2852 NSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKP 2911
            N+ G  +++ +L   G      +T + Q    L    + E      G++PS         
Sbjct: 976  NAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPL----GQKPS--------- 1022

Query: 2912 EWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL--EQGSRFKLTSDFGFV 2969
             +I P+++  ++  G+ +    +V     P  +I+W+ N +++   +   F      G  
Sbjct: 1023 -FIQPLSS-LRVHNGETVRFHARV--SGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMA 1078

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK---DNLIERTQH----------- 3015
             + +VD Y   +G Y+CKA N  GEA  ++T+  T K     L ER +            
Sbjct: 1079 LMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSS 1138

Query: 3016 ---PKGTEG-------LEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI--VDISEG 3063
                   EG       L KI    + L + P      D+ +        K++   DIS G
Sbjct: 1139 SFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMG 1198

Query: 3064 QIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSC 3123
             +A    ++I  G     I+WF+NG  +  S   + V+      L IL TK  D G Y+C
Sbjct: 1199 DVATLSVTVI--GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTC 1256

Query: 3124 RATNKWGQAEISVKLECVDKSKGQK--------------------PRFTTHIQNIEGLKD 3163
             A+N +G+   S  L+   K +G K                    P F   ++ I     
Sbjct: 1257 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIR-CAQ 1315

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS---TRIKTVSDFG-FVVLDIAYTQNHDS 3219
            G  A FE TV  V +P   + W+   + +  S   T I   +  G F+V D    Q  DS
Sbjct: 1316 GLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVND---PQREDS 1370

Query: 3220 GEYVCRAYNKYGEDFTRATI 3239
            G Y+C+A N  GE    A +
Sbjct: 1371 GLYICKAENMLGESTCAAEL 1390



 Score =  128 bits (310), Expect = 4e-28
 Identities = 175/726 (24%), Positives = 286/726 (39%), Gaps = 115/726 (15%)

Query: 3365 RDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTV 3424
            +D  + N +   +   +++ ++ R       +    E + V  ++ S       AP    
Sbjct: 737  KDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQ 796

Query: 3425 PLSNIE--NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI 3482
             L  ++   ++ G+ A F A ++    P  K+ WY   + L  G + +   D     L +
Sbjct: 797  VLQELQPVTVQSGKPARFCAVISGRPQP--KISWYKEEQLLSTGFKCKFLHDGQEYTLLL 854

Query: 3483 SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYS 3542
               +PED+  Y C A N+YG A T+AS+ V+    +  + ++P      I  +       
Sbjct: 855  IEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQ------ 908

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT 3602
               DT+T E   G P                 A F+CR   V+ + ++V W+   K  + 
Sbjct: 909  ---DTVTSE---GQP-----------------ARFQCR---VSGTDLKVSWYSKDKK-IK 941

Query: 3603 GSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL 3661
             SR   +  F     LEI   Y  D G YT  A+N  G+ + +  L ++G          
Sbjct: 942  PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGF--------- 992

Query: 3662 PSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEP 3721
             S F+  T + Q      H    ++ + E        ++   ++ V  G  V F  RV  
Sbjct: 993  -SKFEENTSNSQ-----WHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVS- 1045

Query: 3722 VGDPTMRIDWFHNGRPFATGSRV--HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779
             G P   I WFHN +       V  H     G   + I   Y+  AG+Y+C+A N  G A
Sbjct: 1046 -GIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEA 1104

Query: 3780 TTTAKITCSAKR-DIVLESQLPQGM----------------SGEKIKELERGRISDAPK- 3821
            T  A +T + K  + +L  ++ Q +                 G    EL+  +I++  + 
Sbjct: 1105 TCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLEL 1164

Query: 3822 --EEPIVSTP---------PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK 3870
              E P+ ST          P FI ++ +  +  S G      V     PK +I+W+ NG 
Sbjct: 1165 LSESPVYSTKFDSEKEGTGPIFIKEVSNADI--SMGDVATLSVTVIGIPKPKIQWFFNGV 1222

Query: 3871 LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
            LL     Y+ V+D    SL IL+   ED GEY C A ND+G+    A +           
Sbjct: 1223 LLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI--------- 1273

Query: 3931 NQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMET 3990
            N    G K +E  + +  +++K                   PP F+ +++       +  
Sbjct: 1274 NSKGEGHKDTETESAVAKSLEKLGGPC--------------PPHFLKELKPIRCAQGLPA 1319

Query: 3991 TKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD-FGYVAMNFGWVYPEDSGEYLCR 4049
              FE  +  VG+P   V WF   K L     +T I++  G           EDSG Y+C+
Sbjct: 1320 I-FEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICK 1376

Query: 4050 ATNLYG 4055
            A N+ G
Sbjct: 1377 AENMLG 1382



 Score =  128 bits (310), Expect = 4e-28
 Identities = 158/642 (24%), Positives = 262/642 (40%), Gaps = 81/642 (12%)

Query: 3048 PEFTTVFKDI--VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PE   V +++  V +  G+ A + A +  +G     I W+   + +    + + ++    
Sbjct: 792  PEPPQVLQELQPVTVQSGKPARFCAVI--SGRPQPKISWYKEEQLLSTGFKCKFLHDGQE 849

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKL-----ECVDKSKGQK---PRFTTHIQN 3157
              L ++     D+  Y+C A N +G A  S  L     E V   +      P   T +Q+
Sbjct: 850  YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQD 909

Query: 3158 IEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNH 3217
                 +GQ A F+C V      D+K+ WY   + ++ S   +         L+IA     
Sbjct: 910  TV-TSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPE 965

Query: 3218 DSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTP 3277
            D G Y   A N  G+    +T N   +G    E    +S   +    S +         P
Sbjct: 966  DEGTYTFVASNAVGQ--VSSTANLSLEGFSKFEENTSNSQWHVSLSVSFK-------KEP 1016

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKK-LPHGHRYRTFHD 3336
              + P FI  +  + ++  G++  F AR+  +  P+  ++WF+N +  LP       F +
Sbjct: 1017 LGQKPSFIQPLSSL-RVHNGETVRFHARVSGIPKPE--IQWFHNQQLILPTKDVVFHFEE 1073

Query: 3337 F-GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK--ENLI---LDSQLPRGM 3390
              G+ ++ I+  Y E++G+Y C A N  G  +  A L  T K  E+++   ++ ++   M
Sbjct: 1074 STGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEM 1133

Query: 3391 -----------EGGL-----------EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSN 3428
                       E GL           E L+ L +S V       E+E G  P+F   +SN
Sbjct: 1134 KEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKE-GTGPIFIKEVSN 1192

Query: 3429 IENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPE 3488
             + +  G+ A     +T    P  K++W++NG  L   + ++   D     L I  T  E
Sbjct: 1193 AD-ISMGDVATLS--VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLE 1249

Query: 3489 DSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTL 3548
            D GEY C A N+YG+ + +A +K+  K     E       E  + K  +LE   G     
Sbjct: 1250 DEGEYTCMASNDYGKTICSAYLKINSKG----EGHKDTETESAVAK--SLEKLGGPC--- 1300

Query: 3549 TPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKT 3608
                    PP F      +  ++   A FE  +  V + +  V WF   K L T      
Sbjct: 1301 --------PPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTI 1350

Query: 3609 I-NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            I N  G     +    + D+GLY CKA N  GE+T + +L V
Sbjct: 1351 IHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 1392



 Score =  124 bits (298), Expect = 1e-26
 Identities = 154/651 (23%), Positives = 265/651 (40%), Gaps = 99/651 (15%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++ G  A F A +   G    ++ W K+ + +    +     +     L +      D
Sbjct: 804  VTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 861

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK 1038
            A  YTC A N  G ATTSA+L++   + +  + + P                        
Sbjct: 862  AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP------------------------ 897

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
                P  + PL+ T    EGQ A F+ RV   S   + V WY   K+I  +   +     
Sbjct: 898  -VYPPAIITPLQDT-VTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFE 952

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIE 1158
                L+IA    ED G YT VA NA G+   +A++++E  S  + ++     +  +  + 
Sbjct: 953  DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENT-SNSQWHVSLSVS 1011

Query: 1159 ESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGR 1218
              K  EP+ Q       KP F+QPLS+   V  G+ +    R+   G P   ++WFHN +
Sbjct: 1012 FKK--EPLGQ-------KPSFIQPLSS-LRVHNGETVRFHARVS--GIPKPEIQWFHNQQ 1059

Query: 1219 SV--TVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS-DI 1275
             +  T    F      G   + I+ A S   G+Y+ +A N  G A  +A + V  ++ + 
Sbjct: 1060 LILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPES 1119

Query: 1276 VTDTQNEQAIE-------------QIQLLEDAARRTKQVREDITVM-QAPQFSRALHN-- 1319
            +   + EQ IE             + + L  A  +  ++ E + ++ ++P +S    +  
Sbjct: 1120 ILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEK 1179

Query: 1320 -------IETVEGTNVHL----ECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
                   I+ V   ++ +       +  +G    +++WF NG  +     ++  ++ D  
Sbjct: 1180 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 1239

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK----KDLILESQHPSGLEKIQYL 1424
            +L +L    ED G YTC A+N  G+ + S  L++ +K    KD   ES     LEK+   
Sbjct: 1240 SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKL--- 1296

Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484
                               P F+   K I    +G    FE  +  V +    V WFK  
Sbjct: 1297 --------------GGPCPPHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKEN 1339

Query: 1485 QPVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            + +     +  IH+  G     + D   EDSG+Y C+A N++G    +  L
Sbjct: 1340 KQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 1390



 Score =  121 bits (291), Expect = 7e-26
 Identities = 146/632 (23%), Positives = 247/632 (39%), Gaps = 97/632 (15%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W+   Q +  G + +  HD     L ++  + ED+  Y C+A N  G A  + +
Sbjct: 822  PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 881

Query: 2199 LKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            L V     +  D + P                        + PP  +T L+ T    EG+
Sbjct: 882  LSVEVPEVVSPDQEMP------------------------VYPPAIITPLQDTV-TSEGQ 916

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT-FDFGYVSLDIQHCVPEDAGEYSV 2317
             A F+C+V      +L++ +Y   K ++ +  F +T F+  Y  L+I    PED G Y+ 
Sbjct: 917  PARFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTY-QLEIAEAYPEDEGTYTF 972

Query: 2318 KAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
             A NA+G  +S  ++++         +   +       +  +  FK+    EP+  Q+P 
Sbjct: 973  VASNAVGQVSSTANLSLEGFSKFEENTSNSQW-----HVSLSVSFKK----EPLG-QKPS 1022

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD--FGYVS 2435
            F QPL ++  +  G+T  F  R+   G P  +++WF N++LI  +  +    +   G   
Sbjct: 1023 FIQPLSSL-RVHNGETVRFHARVS--GIPKPEIQWFHNQQLILPTKDVVFHFEESTGMAL 1079

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXX-----------XIQLETQH---- 2480
            M I     E  G Y C+A+N  GE                         I++E +     
Sbjct: 1080 MLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSS 1139

Query: 2481 -----PEGMK----KIQKLEQPHERRSEEP--------DREFEKPIFTQVLTGPSELWEG 2523
                  EG+     ++ K+ +  E  SE P        ++E   PIF + ++  +++  G
Sbjct: 1140 FLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSN-ADISMG 1198

Query: 2524 QHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583
              A     V+  G P  + +W+ NGV L   + ++   D    +L I      D G Y C
Sbjct: 1199 DVATLSVTVI--GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTC 1256

Query: 2584 KAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPI 2643
             A N  G                     + E  +  + + A    + ++    G    P 
Sbjct: 1257 MASNDYGKTICSAYLKINS---------KGEGHKDTETESAVAKSLEKL----GGPCPPH 1303

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD-FGLVTL 2702
            F   LK   +  +G     E  V     P   + WFK    L T        +  G  T 
Sbjct: 1304 FLKELKPI-RCAQGLPAIFEYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTF 1360

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +N  + +DSG+Y CKA N+LGE+   A + +
Sbjct: 1361 IVNDPQREDSGLYICKAENMLGESTCAAELLV 1392



 Score =  120 bits (288), Expect = 2e-25
 Identities = 138/528 (26%), Positives = 204/528 (38%), Gaps = 66/528 (12%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P    PL +     EG+ A F+ R++ TD   LKV WY   K +K    FR         
Sbjct: 901  PAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFRMTQFEDTYQ 956

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            LEI+  YPED G Y   A N  G+  +TA++ ++G           K  E T +      
Sbjct: 957  LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEG---------FSKFEENTSNS----- 1002

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
             +  ++     +   G  P F    S L +    +  F  R+  +      ++WFHN + 
Sbjct: 1003 QWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGI--PKPEIQWFHNQQL 1060

Query: 3600 LLTGSRV--KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV--KGRQGI 3655
            +L    V        G  ++ I   Y   AG Y+CKA N  GEAT +  L V  K  + I
Sbjct: 1061 ILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESI 1120

Query: 3656 ILE----------PQLPSHFKSGTES--------IQKLEETLHKREEITI-----EDEKP 3692
            + E           +  S F S  E         + K+ ETL    E  +     + EK 
Sbjct: 1121 LHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFDSEKE 1180

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
                  ++   N D+  G        V  +G P  +I WF NG      +    + D   
Sbjct: 1181 GTGPIFIKEVSNADISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDD 1238

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
             +L I +    D GEYTC A+N +G      K  CSA   I           GE  K+ E
Sbjct: 1239 HSLIILFTKLEDEGEYTCMASNDYG------KTICSAYLKI--------NSKGEGHKDTE 1284

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
                     E+     PP F+ ++K     +     FE  V  +  P   + W++  K L
Sbjct: 1285 TESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPT--VTWFKENKQL 1342

Query: 3873 PSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             +   Y  +++  G  +  +     EDSG YIC+A N  GE    A +
Sbjct: 1343 CTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 1390



 Score =  114 bits (274), Expect = 9e-24
 Identities = 130/524 (24%), Positives = 216/524 (41%), Gaps = 68/524 (12%)

Query: 3683 EEITIEDEKP-NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            E ++ + E P  PP     ++D +   EG P  F CRV       +++ W+   +     
Sbjct: 888  EVVSPDQEMPVYPPAIITPLQDTV-TSEGQPARFQCRVSGTD---LKVSWYSKDKKIKP- 942

Query: 3742 SRVHTLNDF-GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800
            SR   +  F     L+I   Y  D G YT  A+N  G  ++TA ++          S+  
Sbjct: 943  SRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGF------SKFE 996

Query: 3801 QGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPK 3860
            +  S  +        +S + K+EP+    P FI  + S  V   E VRF  RV     PK
Sbjct: 997  ENTSNSQWHV----SLSVSFKKEPL-GQKPSFIQPLSSLRVHNGETVRFHARVSGI--PK 1049

Query: 3861 LRIEWYRNGKL-LPSGHR-YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKAT 3918
              I+W+ N +L LP+    +      G   + I+  Y+E +G+Y C+A N  GE    AT
Sbjct: 1050 PEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAAT 1109

Query: 3919 IS-CKKLPDIILQNQVPRGMK-------------RSEALTQMEATIKKYTSEV-YLTEDD 3963
            ++   K P+ IL  ++ + ++               E L   E  + K    +  L+E  
Sbjct: 1110 LTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESP 1169

Query: 3964 LY----DVDKK-QPPRFVTQI-QSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLL 4017
            +Y    D +K+   P F+ ++  +  S+ ++ T      +  +G P  K++WFFNG  L 
Sbjct: 1170 VYSTKFDSEKEGTGPIFIKEVSNADISMGDVAT----LSVTVIGIPKPKIQWFFNGVLLT 1225

Query: 4018 HKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQL 4077
                +  ++D    ++   +   ED GEY C A+N YG     A +K   K     D++ 
Sbjct: 1226 PSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTET 1285

Query: 4078 PKHM-KSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTG 4136
               + KS+EK+                     CPP F+     +   +G  A F   V G
Sbjct: 1286 ESAVAKSLEKL------------------GGPCPPHFLKELKPIRCAQGLPAIFEYTVVG 1327

Query: 4137 HPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYDTG 4178
             P P V W      +     Y + +  +G   F +   ++ D+G
Sbjct: 1328 EPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 1371



 Score =  109 bits (263), Expect = 2e-22
 Identities = 134/597 (22%), Positives = 230/597 (38%), Gaps = 87/597 (14%)

Query: 3643 VSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETL---HKREEITIEDEKPNPPRFTV 3699
            +    QV+ R   ++E ++   F S T      E T      R  +T+    P PP+   
Sbjct: 740  IEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQ 799

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
            E++  + V  G P  F C V   G P  +I W+   +  +TG +   L+D     L +  
Sbjct: 800  ELQP-VTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE 856

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
             +  DA  YTC A N +G ATT+A           L  ++P+ +S +             
Sbjct: 857  AFPEDAAVYTCEAKNDYGVATTSAS----------LSVEVPEVVSPD------------- 893

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
             +E P+   PP  IT ++     E +  RF+CRV   +   L++ WY   K +     +R
Sbjct: 894  -QEMPVY--PPAIITPLQDTVTSEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFR 947

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
                     L+I   Y ED G Y   A N  G+  + A +S +        ++       
Sbjct: 948  MTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGF------SKFEENTSN 1001

Query: 3940 SEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAP 3999
            S+    +  + KK         + L      Q P F+ Q  S   +   ET +F  +++ 
Sbjct: 1002 SQWHVSLSVSFKK---------EPL-----GQKPSFI-QPLSSLRVHNGETVRFHARVS- 1045

Query: 4000 VGDPNMKVEWFFNGKPLLHKNRFTPIYD--FGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057
             G P  +++WF N + +L        ++   G   M     Y E +G+Y C+A N  G  
Sbjct: 1046 -GIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEA 1104

Query: 4058 ETKAVIKTTGK--PGIVY---DSQLPKHMKSIE----------------KIREMEASWQV 4096
               A +  T K    I++   + ++   MK                   ++ ++  + ++
Sbjct: 1105 TCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLEL 1164

Query: 4097 TPEQVV-----EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
              E  V     +  K    P+F+       +  G+ A     V G PKP++ W  NG  +
Sbjct: 1165 LSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLL 1224

Query: 4152 VNGSRYKLTYDGMYH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR 4207
               + YK  +DG  H   I  T+  D G+   +             LK+  + + ++
Sbjct: 1225 TPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK 1281



 Score = 97.9 bits (233), Expect = 8e-19
 Identities = 156/676 (23%), Positives = 264/676 (39%), Gaps = 99/676 (14%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PPQ +  L+ VT   G    F   I   G P  KI W K  Q +    +   +      +
Sbjct: 794  PPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 851

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L ++    +D+  YTC A +  GVA T A L V          + PE +   Q++  Y  
Sbjct: 852  LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQEMPVYP- 900

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                          P  I PLQD     EG+ A F+ +   VS   ++V WY   + I  
Sbjct: 901  --------------PAIITPLQDT-VTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 942

Query: 816  SS--RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLG 873
            S   R+T  F   Y  L I     ED G+YT  A N +G+  STA++ +   S       
Sbjct: 943  SRFFRMTQ-FEDTY-QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFS------- 993

Query: 874  IPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARL 933
                 ++ E T                 +    QKP F  P+   + +  G    F AR+
Sbjct: 994  -----KFEENTSNSQWHVSLSVSFKKEPLG---QKPSFIQPLSS-LRVHNGETVRFHARV 1044

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFF--NFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
              I      ++W  + + +  +  +   F  + G   + I       AG Y+C+A N+ G
Sbjct: 1045 SGIPKP--EIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAG 1102

Query: 992  QATTSANLTIVTK--KDIIAES-QHPGGLEKIQY-----------LEDAS-RYSKRTEEE 1036
            +AT +A LT+  K  + I+ E  +    +E  ++           L  A  + SK  E  
Sbjct: 1103 EATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETL 1162

Query: 1037 VKITQKP----RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTV--------EWYFNGK 1084
              +++ P    +F    +GT  I   + ++ +  +   + L++TV        +W+FNG 
Sbjct: 1163 ELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGV 1222

Query: 1085 QITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTS 1144
             +T +   +   D    +L I   + ED G YT +A N  G+   SA + + ++      
Sbjct: 1223 LLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG----- 1277

Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPM 1204
                G  +       +K +E +          P F++ L    P+   + +        +
Sbjct: 1278 ---EGHKDTETESAVAKSLEKLG-----GPCPPHFLKELK---PIRCAQGLPAIFEYTVV 1326

Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIH-ATSADTGEYTVRAVNHLGSAHT 1263
            G+P   V WF   + +     +   ++       I++     D+G Y  +A N LG +  
Sbjct: 1327 GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTC 1386

Query: 1264 SAIVRVIERSDIVTDT 1279
            +A + V+     +TDT
Sbjct: 1387 AAELLVLLEDTDMTDT 1402



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 66/243 (27%), Positives = 108/243 (44%), Gaps = 10/243 (4%)

Query: 241  TKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF 300
            T   + ES V  ST+ D       P  I ++  N+ +  G  A   V + G P+P++ WF
Sbjct: 1161 TLELLSESPVY-STKFDSEKEGTGPIFI-KEVSNADISMGDVATLSVTVIGIPKPKIQWF 1218

Query: 301  KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             NG  L  S  ++ +   +  +L +  T+  D G YT +A N  G  + S YL + S  E
Sbjct: 1219 FNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 1278

Query: 361  SYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPY 420
             +         T+T+     + +E       P F+K  +     +G    F+  V G P 
Sbjct: 1279 GHKD-------TETES-AVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPA 1330

Query: 421  PEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            P VTWF  ++Q+     + I+ N +G+   ++ +    DSG+  C A N  GE+     L
Sbjct: 1331 PTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 1390

Query: 481  NVI 483
             V+
Sbjct: 1391 LVL 1393



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 105/404 (25%), Positives = 168/404 (41%), Gaps = 44/404 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P + T  ++     E +   FEV  + E +   KW +    IK++   Q+ T      L 
Sbjct: 524  PIMITSMLKDINAEEKDTITFEVTVNYEGISY-KWLKNGVEIKSTDKCQMRTKKLTHSLN 582

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            IR V   D+A +  VA    G A  +A L VE +  + R  I         +++ V   +
Sbjct: 583  IRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHI---------KDIKVLEKK 629

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
                + +V+    I V W+K+ +++Q   R KI +E   + LLI      D+GKY  VA 
Sbjct: 630  RAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAG 688

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
             +   A+   E        +D    + ++     ++IE  K + V     +EF    V +
Sbjct: 689  GNVSTAKLFVE-------GRDV---RIRSIKKEVQVIE--KQRAV-----VEFE---VNE 728

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                  WYK    I      +     +   + + ISE    D G+Y  VA  +   VT  
Sbjct: 729  DDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT-- 786

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              L V  P+    L  L P   + V  G+PA+F   I+ + +P I W +E  L+      
Sbjct: 787  --LYVNAPEPPQVLQELQP---VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 841

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + +H+G    LL+   + ED   +TC A    G   TSA L V+
Sbjct: 842  KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 885



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 61/214 (28%), Positives = 96/214 (44%), Gaps = 12/214 (5%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P F     N +++ G +  L   V G     + W  NG  + P    K + +   ++L+I
Sbjct: 1184 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 1243

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA----------PP 4623
            L    +D G+Y C+A N  G+  C A   ++      K   +T++A A          PP
Sbjct: 1244 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK-DTETESAVAKSLEKLGGPCPP 1302

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRI 4682
              ++ LK    A+G    F   +VG+P PTV W+K +K +  S Y+ +    +   T  +
Sbjct: 1303 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 1362

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            ++   ED G Y C A N  G  T AA+L V   D
Sbjct: 1363 NDPQREDSGLYICKAENMLGESTCAAELLVLLED 1396



 Score = 85.0 bits (201), Expect = 6e-15
 Identities = 66/267 (24%), Positives = 115/267 (43%), Gaps = 8/267 (2%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV PP I    +++   EG  A+FQ ++SG    +V+W+   +++  S    +    +  
Sbjct: 897  PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 955

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
             L +      D G YT +A N  G + ++  L++E  ++       SQ+         +E
Sbjct: 956  QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKE 1015

Query: 382  RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
               + +K   P F++      V  G+  RF  RV+G P PE+ WF N + I    +    
Sbjct: 1016 --PLGQK---PSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFH 1070

Query: 442  VNESGNHALM-ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK-EQVVAPKFVERFST 499
              ES   ALM I +     +G  +C A N +GE      L V  K  + +  + +E+   
Sbjct: 1071 FEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIE 1130

Query: 500  LNVREGEPVVLNARAVGTPTPRITWQK 526
            + ++E     L+A   G  +  +   K
Sbjct: 1131 MEMKEFSSSFLSAEEEGLHSAELQLSK 1157



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 53/209 (25%), Positives = 97/209 (46%), Gaps = 21/209 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P  I+ + +  ++ G     S  ++G P P +QW+    L+ PS  ++     D+++L I
Sbjct: 1184 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 1243

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-----------TQPDQADNLPAL------- 4724
                 EDEG+Y C+A N  G+   +A LK+           T+   A +L  L       
Sbjct: 1244 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 1303

Query: 4725 --TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIG 4781
                L+ I   +G PA F+  +  +  PT+ W +E   +  +  + +IH  N +   ++ 
Sbjct: 1304 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 1363

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED+G + C+A    G+   +A+L+V
Sbjct: 1364 DPQREDSGLYICKAENMLGESTCAAELLV 1392



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 98/399 (24%), Positives = 165/399 (41%), Gaps = 52/399 (13%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            KK +     E+    FEV    + +P +KW+ +N  IK S   ++ +      L+++ + 
Sbjct: 355  KKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 413

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
              D+  + AV     G  +C A L VE               T T +N+ V   +    +
Sbjct: 414  PSDAGEYTAVV----GQLECKAKLFVETLH-----------ITKTMKNIEVPETKTASFE 458

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +V+    +   WLKNG +++   + KI+ +   + L+I+    +DS +Y  V     G 
Sbjct: 459  CEVSHFN-VPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGN 513

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V+                 P  I   LKD    E   I F   +  + + + 
Sbjct: 514  DQVSATLTVT-----------------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SY 555

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W K    IK +   QM      ++L I      D  DY  V    AG+ T  A L V  
Sbjct: 556  KWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFV----AGKATSTATLYV-- 609

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
              +A ++     ++DI V E + A F+ ++ S+   T+QW+++   +  T   ++  E  
Sbjct: 610  --EARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 666

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               LLI +T   D G +T     A G V T AKL V+ +
Sbjct: 667  VHRLLIPSTRMSDAGKYT---VVAGGNVST-AKLFVEGR 701



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 76/294 (25%), Positives = 127/294 (43%), Gaps = 41/294 (13%)

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580
            ++VNV  G    L+ KV+      V W  N ++++PD R + + +     L+I   +  D
Sbjct: 8    KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASD 67

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
             G Y+ +        R +  C +S+   K               II  L+D    E Q +
Sbjct: 68   EGPYKLIV------GRVETNCNLSVEKIK---------------IIRGLRDLTCTETQNV 106

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
             F  ++    +  V W   DK IKPS  +++      Y L +     +DEG Y   A  +
Sbjct: 107  VFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGEN 165

Query: 4701 --AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
              +G++TVA                  PL D  V E Q A F+ ++ +      +WLR+G
Sbjct: 166  ITSGKLTVAGGA------------ISKPLTDQTVAESQEAVFECEVANPDSKG-EWLRDG 212

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              +P T + +   +G+   L+I  T  +D G +T +  T+    +TSAKL V++
Sbjct: 213  KHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKVEA 262



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 100/390 (25%), Positives = 151/390 (38%), Gaps = 49/390 (12%)

Query: 2204 HRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFE 2263
            HR  I +T+  +  E          S  + V  P+  PP+ + EL+  T V  GK A F 
Sbjct: 759  HRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPE--PPQVLQELQPVT-VQSGKPARF- 814

Query: 2264 CQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINAL 2323
            C V     P  +I +Y   + L +  +     D    +L +    PEDA  Y+ +A N  
Sbjct: 815  CAVISGR-PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 873

Query: 2324 GHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQ 2383
            G  T++ S++V            PE +   +E+        P  P       P    PLQ
Sbjct: 874  GVATTSASLSVEV----------PEVVSPDQEM--------PVYP-------PAIITPLQ 908

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            +     EGQ A F CR   V    LKV W+  +K I+ S     T       + I+    
Sbjct: 909  DTVT-SEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 964

Query: 2444 EDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDR 2503
            EDEG Y   ASN +G+               +  T + +    +          S + + 
Sbjct: 965  EDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSV--------SFKKEP 1016

Query: 2504 EFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSR---FRTT 2560
              +KP F Q L+    +  G+   + ARV   G P    +W+ N  +L + ++   F   
Sbjct: 1017 LGQKPSFIQPLSS-LRVHNGETVRFHARV--SGIPKPEIQWFHN-QQLILPTKDVVFHFE 1072

Query: 2561 HDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
               G   + I    +  AG Y CKA N AG
Sbjct: 1073 ESTGMALMLIVDAYSEHAGQYSCKAANSAG 1102



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 67/233 (28%), Positives = 100/233 (42%), Gaps = 22/233 (9%)

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIV----PPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            E    +++     V   K ++  GG +    P   T     V+   G +V L T +T  K
Sbjct: 1939 EKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAK 1997

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD-SGKYECVAINSAGEARCDAE 4600
              +V W    K V  D + K L++  TYTL+I +   +D  G+Y C A+N +G+    A+
Sbjct: 1998 --EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAK 2055

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V             +AA      IEPL+   VA G   +F+C+I   P    QW+K  
Sbjct: 2056 LTVV-----------KRAAPVIKRKIEPLE---VALGHLAKFTCEIQSAPNVRFQWFKAG 2101

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + I  S    +  +    +L I      D G+Y C A N  G V+  A L VT
Sbjct: 2102 REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 2154



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 73/237 (30%), Positives = 102/237 (43%), Gaps = 16/237 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI+WF NGV LT  A  K  FD    +L I   + +D G YTC A+N  G+ + +A 
Sbjct: 1211 PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAY 1270

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            +KI  +    GE  H D+ +   A+                   F+  L  I C +G   
Sbjct: 1271 LKINSK----GEG-HKDT-ETESAVAKSLEKLGGPCPPH-----FLKELKPIRCAQGLPA 1319

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE-EDSGIYTCKA 2850
             FE  V     PT  + WF  NK L +   Y   H+ +     I +  + EDSG+Y CKA
Sbjct: 1320 IFEYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKA 1377

Query: 2851 TNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTE 2907
             N  G +T +  L    +     DT   + K+  EA E   +  L KG      D+E
Sbjct: 1378 ENMLGESTCAAELLVLLEDTDMTDTP-CKAKSTPEAPEDFPQTPL-KGPAVEALDSE 1432



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 56/189 (29%), Positives = 83/189 (43%), Gaps = 6/189 (3%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I  PL D +  EG  +  +  I       V WY  +KL+   + F+  +  + YTL I
Sbjct: 1970 PMIHTPLVDTVSEEGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVI 2027

Query: 4683 SEAFPED-EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
             +   ED +G+Y C A N +G+   +AKL V +         + PL    V  G  A+F 
Sbjct: 2028 DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLE---VALGHLAKFT 2084

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +I S      QW + G  I E+    +      + L I  T   D G +TC+A+   G 
Sbjct: 2085 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 2144

Query: 4802 VETSAKLVV 4810
            V  +A L V
Sbjct: 2145 VSCTATLTV 2153



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 65/248 (26%), Positives = 96/248 (38%), Gaps = 19/248 (7%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K    PIF K++    +   + A   V   G P P I+W+     +  S D++       
Sbjct: 1179 KEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDD 1238

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR---------------GG 4510
              LII    +ED   +  +A N  G   CSA L +  K    +               GG
Sbjct: 1239 HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 1298

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTY 4569
              PP F    + +    G     +  V G     V W K  K++   +   I+   +G+ 
Sbjct: 1299 PCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 1358

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT--KDKPKPQTKAANAPPEIIE 4627
            T ++ +   +DSG Y C A N  GE+ C AE +V L  T   D P        AP +  +
Sbjct: 1359 TFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQ 1418

Query: 4628 -PLKDKIV 4634
             PLK   V
Sbjct: 1419 TPLKGPAV 1426



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 63/232 (27%), Positives = 94/232 (40%), Gaps = 24/232 (10%)

Query: 3011 ERTQHPKGTEGLE--KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHY 3068
            E +    GTE +   KIQ  E    KE G          P   T   D V   EG I H 
Sbjct: 1941 EESSSESGTEEVATVKIQEAEGGFIKEDG----------PMIHTPLVDTVS-EEGDIVHL 1989

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD-SGTYSCRATN 3127
              S+    +    + W++  K + +  + + +       L I    T D  G Y C A N
Sbjct: 1990 TTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALN 2045

Query: 3128 KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187
              G+   S KL  V ++    P     I+ +E +  G  A F C +     P+++ +W+ 
Sbjct: 2046 DSGKTATSAKLTVVKRAA---PVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFK 2099

Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
             G+ +  S +    S      L+I  TQ  D GEY C+A N+YG     AT+
Sbjct: 2100 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 2151



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 48/175 (27%), Positives = 72/175 (41%), Gaps = 7/175 (4%)

Query: 405  EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVV 463
            EG +      +T     EV W+  ++ +  D   K L +++  + L+I  V   D  G  
Sbjct: 1983 EGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEY 2039

Query: 464  TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
             C A N SG+TA   +L V+++    AP    +   L V  G            P  R  
Sbjct: 2040 VCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQ 2096

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            W K G  I  + +  I +    S+L+I R +  D   Y C A N  GS +  A L
Sbjct: 2097 WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 2151



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 94/396 (23%), Positives = 156/396 (39%), Gaps = 52/396 (13%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            ++   V E  +A  E +     +  +KWY  +  IK     Q     TK  L+I +    
Sbjct: 7    LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 66

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D   +  +     G  + + NL VE K +  RG           +++  T  Q V  + +
Sbjct: 67   DEGPYKLIV----GRVETNCNLSVE-KIKIIRG----------LRDLTCTETQNVVFEVE 111

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            ++ +  IDV W    K+++P  + KI      Y L +L     D GKY       AGE  
Sbjct: 112  LSHSG-IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFY----AGENI 166

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               +  V                 A   I +PL D+ VAE Q   F C+ V  P    +W
Sbjct: 167  TSGKLTV-----------------AGGAISKPLTDQTVAESQEAVFECE-VANPDSKGEW 208

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  K +  +   +      +  L I+    +D G+Y    Y  A   T +AKLKV    
Sbjct: 209  LRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY---TYKVATSKT-SAKLKV---- 260

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
              + +     L+++ V E Q A F  ++T      +QW++ G ++     + +  +G   
Sbjct: 261  --EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIY 318

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             L I N    D   +  R     G++  SA+L V++
Sbjct: 319  SLRIKNCAIVDESVYGFR----LGRLGASARLHVET 350



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 90/387 (23%), Positives = 147/387 (37%), Gaps = 46/387 (11%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            +Y   A R        V   + P+ L  L+    +  G+ A F A +  +      + WY
Sbjct: 773  EYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVT-VQSGKPARFCAVISGRPQ--PKISWY 829

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
               + +++  + +  HD     L +     ED+ VYT  A+N  G A  SAS++VE    
Sbjct: 830  KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV--- 886

Query: 1141 IDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECR 1200
                                + V P    +E+    P  + PL +    SEG+    +CR
Sbjct: 887  -------------------PEVVSP---DQEMPVYPPAIITPLQD-TVTSEGQPARFQCR 923

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
               +    ++V W+   + +     F+         L+I  A   D G YT  A N +G 
Sbjct: 924  ---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ 980

Query: 1261 AHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNI 1320
              ++A + +   S    +T N Q    + L     +          + Q P F + L ++
Sbjct: 981  VSSTANLSLEGFSKFEENTSNSQ--WHVSLSVSFKKE--------PLGQKPSFIQPLSSL 1030

Query: 1321 ETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI-KTGHRFRPAYEFDYVALDLL-SVYPE 1378
                G  V    R+   G     ++WF N + I  T        E   +AL L+   Y E
Sbjct: 1031 RVHNGETVRFHARVS--GIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSE 1088

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAK 1405
             +G Y+C+A N  GEA  +  L V  K
Sbjct: 1089 HAGQYSCKAANSAGEATCAATLTVTPK 1115



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 92/397 (23%), Positives = 156/397 (39%), Gaps = 53/397 (13%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            +K +    V E ++A FE E    P    +W R+   +  + + +  +   K  LII   
Sbjct: 179  SKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAAT 237

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             ++D   +      +  T+K SA L VE  +              T +N+ VT  Q    
Sbjct: 238  KLDDIGEYTY----KVATSKTSAKLKVEAVK-----------IKKTLKNLTVTETQDAVF 282

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              ++T      V W+KNG  ++ + +  I  +   Y+L I      D   Y         
Sbjct: 283  TVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGA 342

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR   E V                     +II+  KD    E   + F   +    +P 
Sbjct: 343  SARLHVETV---------------------KIIKKPKDVTALENATVAFEVSVSHDTVP- 380

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            V+W+  +  IKPS   ++      + L +    P D G+Y  V     G++   AKL V 
Sbjct: 381  VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFV- 435

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
                 + L     +++I V E + A F+ +++    P++ WL+ G  I  +  F+++ +G
Sbjct: 436  -----ETLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG 489

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                L+I NT  ED+  +    T   G  + SA L V
Sbjct: 490  KLHQLIIMNTSTEDSAEY----TFVCGNDQVSATLTV 522



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 52/187 (27%), Positives = 80/187 (42%), Gaps = 15/187 (8%)

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
            ++I PLKD  V EG      CK+    + +V+WY  D+ IKP    Q      +  L I+
Sbjct: 2    DVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVIN 61

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                 DEG YK +     GRV     L V      + +  +  LRD+   E Q   F+ +
Sbjct: 62   RTHASDEGPYKLI----VGRVETNCNLSV------EKIKIIRGLRDLTCTETQNVVFEVE 111

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            + S     + W  +   I  +  +++   G    L + N  ++D G +    T  AG+  
Sbjct: 112  L-SHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKY----TFYAGENI 166

Query: 4804 TSAKLVV 4810
            TS KL V
Sbjct: 167  TSGKLTV 173



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 82/307 (26%), Positives = 134/307 (43%), Gaps = 46/307 (14%)

Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
           ++ K+ E   A F+ ++S  P   V W K+ Q L  +++ +I        L + +T+ SD
Sbjct: 621 KDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 679

Query: 333 SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
           +G YT++A    G  V++  L VE                D + R  ++ +++ EK  A 
Sbjct: 680 AGKYTVVA----GGNVSTAKLFVEG--------------RDVRIRSIKKEVQVIEKQRAV 721

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
              +V +D DV              +   E+ + + +R       HK +V E   H + I
Sbjct: 722 VEFEVNED-DVDAHWY---------KDGIEINFQVQER-------HKYVV-ERRIHRMFI 763

Query: 453 TNVTLSDSGVVTCVA-RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           +    SD+G  T VA RN+S  T +   +N  E  QV+     +    + V+ G+P    
Sbjct: 764 SETRQSDAGEYTFVAGRNRSSVTLY---VNAPEPPQVL-----QELQPVTVQSGKPARFC 815

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
           A   G P P+I+W K+   +    + +   DG   TL +  A   DAA Y C A+N  G 
Sbjct: 816 AVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGV 875

Query: 572 TATRARL 578
             T A L
Sbjct: 876 ATTSASL 882



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 105/508 (20%), Positives = 194/508 (38%), Gaps = 58/508 (11%)

Query: 4306 GDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQ 4365
            G+ +TS  +  +     +   DQT   +++ V +     P      E    GK + +   
Sbjct: 163  GENITSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANP--DSKGEWLRDGKHLPLTNN 220

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
             +++ +    + I       +  E  +K  T +   +  V+  K     K ++   V E 
Sbjct: 221  IRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVK---IKKTLKNLTVTET 277

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            + A F VE     +  ++W +    ++++  + I    T   L I+   + D +V+    
Sbjct: 278  QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGF-- 335

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
              R G    SA L VE  +      I  P      +N  V     V  DT       + V
Sbjct: 336  --RLGRLGASARLHVETVKI-----IKKPKDVTALENATVAFEVSVSHDT-------VPV 381

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W     +++P  +++++ E   + L++    P D+G+Y  V     G+  C A+  V  
Sbjct: 382  KWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVE- 436

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                               I + +K+  V E +   F C++    +P++ W K    I+ 
Sbjct: 437  ----------------TLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEM 479

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+ F++      + L I     ED  +Y  V     G   V+A L VT       +   +
Sbjct: 480  SEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGNDQVSATLTVTP------IMITS 529

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             L+DI   E     F+  +  +   + +WL+ G  I  T   QM  +     L I N + 
Sbjct: 530  MLKDINAEEKDTITFEVTVNYE-GISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHF 588

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             D   +    T  AG+  ++A L V+++
Sbjct: 589  GDAADY----TFVAGKATSTATLYVEAR 612



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 5/125 (4%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            +I  K    + TE E         + GP     PP F K+++P R  +   A FE    G
Sbjct: 1272 KINSKGEGHKDTETESAVAKSLEKLGGPC----PPHFLKELKPIRCAQGLPAIFEYTVVG 1327

Query: 4437 EPLPLIKWYRENFPIKNSPDFQ-IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            EP P + W++EN  +  S  +  IH  +     I+     EDS ++   AEN  G + C+
Sbjct: 1328 EPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCA 1387

Query: 4496 ANLVV 4500
            A L+V
Sbjct: 1388 AELLV 1392



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 54/213 (25%), Positives = 85/213 (39%), Gaps = 15/213 (7%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EGQ    + +V   TD  LK+ W+     +      + T       L I     +D G Y
Sbjct: 914  EGQPARFQCRVSG-TD--LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 970

Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXV 2775
            T  A+N +G+  STA++ +E      G S   ++     +                    
Sbjct: 971  TFVASNAVGQVSSTANLSLE------GFSKFEENTS--NSQWHVSLSVSFKKEPLGQKPS 1022

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNK-PLPS-GTRYKSTHDFSYVSL 2833
            FI  L+++    G+ + F   V  S  P  +I+WF N +  LP+    +          +
Sbjct: 1023 FIQPLSSLRVHNGETVRFHARV--SGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALM 1080

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
             I   Y E +G Y+CKA NS G AT + +L  T
Sbjct: 1081 LIVDAYSEHAGQYSCKAANSAGEATCAATLTVT 1113



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 1/92 (1%)

Query: 67   GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
            G P PP F +  K  R AQG  A FE  + G P P V+W ++   L     Y++ +N   
Sbjct: 1297 GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHN-PN 1355

Query: 127  GDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            G  + ++      D G Y C A N  GE+ C+
Sbjct: 1356 GSGTFIVNDPQREDSGLYICKAENMLGESTCA 1387



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            E + PIF +   NA  + G  A     + G P P + W      L     Y   ++    
Sbjct: 1180 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD-- 1237

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            D SL+I      DEGEYTC A N YG+ ICS Y++
Sbjct: 1238 DHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLK 1272



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 56/207 (27%), Positives = 87/207 (42%), Gaps = 24/207 (11%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI+W+FNG +L   + +K   D    +L ++     D G YTC A N  G+   S+ 
Sbjct: 1211 PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAY 1270

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            +   SK          +G +  E    +  SL K  G         PP F    K I   
Sbjct: 1271 LKINSKG---------EGHKDTETESAVAKSLEKLGGP-------CPPHFLKELKPI-RC 1313

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSG 3119
            ++G  A +E +++  G+ +  + WF   K +  S     ++   G     +   +  DSG
Sbjct: 1314 AQGLPAIFEYTVV--GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 1371

Query: 3120 TYSCRATNKWGQ----AEISVKLECVD 3142
             Y C+A N  G+    AE+ V LE  D
Sbjct: 1372 LYICKAENMLGESTCAAELLVLLEDTD 1398



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +  L  +  + G    F C V   R P  KI W+   + L +G + K  HD    +L + 
Sbjct: 798  LQELQPVTVQSGKPARF-CAVISGR-PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI 855

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSL 2863
              + ED+ +YTC+A N  G ATTS SL
Sbjct: 856  EAFPEDAAVYTCEAKNDYGVATTSASL 882



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 96/395 (24%), Positives = 167/395 (42%), Gaps = 34/395 (8%)

Query: 1424 LEDTSRYK-KTDIIDESVTIKPRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLK-VE 1479
            L+D   Y  K      S  +K   V   K+++N  V E Q   F  +L   T  N+K V+
Sbjct: 239  LDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL---THPNVKGVQ 295

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W KNG  +    ++         +L I +    D  +Y  R    +G    S RL    T
Sbjct: 296  WIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFR----LGRLGASARLHVE-T 350

Query: 1540 TDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599
              I++  ++   LE   V  + S  H T  V        I   S K+  + E +      
Sbjct: 351  VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEI-KPSDKHRLVSERKVHKLML 409

Query: 1600 RLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPED-SGTYTCRA--I 1655
            + I  SDA    E+      L+  ++ F ET +      +I   +PE  + ++ C     
Sbjct: 410  QNISPSDAG---EYTAVVGQLECKAKLFVETLHITKTMKNIE--VPETKTASFECEVSHF 464

Query: 1656 NALGEAVTSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV---ITQAP 1711
            N     + +G+ I  S+K  I ++ +    +      ED+++Y      D+V   +T  P
Sbjct: 465  NVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTP 524

Query: 1712 VF-TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            +  T  +KDI   E     FE   + V    +  +WL+NGV I+++++          +L
Sbjct: 525  IMITSMLKDINAEEKDTITFE---VTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSL 581

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            N++ V+  D+  YT  A    G+A +++TL+V+++
Sbjct: 582  NIRNVHFGDAADYTFVA----GKATSTATLYVEAR 612



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/79 (32%), Positives = 40/79 (50%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G  A     +    KP IQW   G L+  + D++ + +G++  L+I  T  ED G +TC 
Sbjct: 1198 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 1257

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            A+   G+   SA L + SK
Sbjct: 1258 ASNDYGKTICSAYLKINSK 1276



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L + V +EGD +H   ++  +++    + W+F NK +PS  ++K   D +  +L I    
Sbjct: 1976 LVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVN 2031

Query: 2840 EED-SGIYTCKATNSKGSATTSGSL 2863
             ED  G Y C+A N  G   TS  L
Sbjct: 2032 TEDHQGEYVCEALNDSGKTATSAKL 2056



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 3/115 (2%)

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            + L DS +      + V    AP    ++  P +++ G  A + C I+  P  N+R +W+
Sbjct: 2042 EALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSAP--NVRFQWF 2098

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
              G+ +    +    +    ++L+IL     D GEYTCKA N  G    +  L V
Sbjct: 2099 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 14/128 (10%)

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866
            KI+E E G I +   + P++ TP      +     EE + V     +   ++    + WY
Sbjct: 1956 KIQEAEGGFIKE---DGPMIHTP------LVDTVSEEGDIVHLTTSITNAKE----VNWY 2002

Query: 3867 RNGKLLPSGHRYRTVYDMGFVSLDILYVYAED-SGEYICRAVNDFGEDFTKATISCKKLP 3925
               KL+PS  +++ + D    +L I  V  ED  GEY+C A+ND G+  T A ++  K  
Sbjct: 2003 FENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 2062

Query: 3926 DIILQNQV 3933
              +++ ++
Sbjct: 2063 APVIKRKI 2070



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 24/87 (27%), Positives = 37/87 (42%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F Q   + R   G   +F  ++ G P P + W   +  ++        + E TG   +
Sbjct: 1021 PSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALM 1080

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            LI        G+Y+C A N  GEA C+
Sbjct: 1081 LIVDAYSEHAGQYSCKAANSAGEATCA 1107



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 2/82 (2%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V  G    F C ++    P +R  WF  GR      +    +     +L+I      D
Sbjct: 2073 LEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVD 2130

Query: 3765 AGEYTCRATNKWGSATTTAKIT 3786
             GEYTC+A+N++GS + TA +T
Sbjct: 2131 CGEYTCKASNEYGSVSCTATLT 2152



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 38/164 (23%), Positives = 60/164 (36%), Gaps = 9/164 (5%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVV 4500
            + WY EN  + +   F+         L+I +V  ED    +   A N  G    SA L V
Sbjct: 1999 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 2058

Query: 4501 EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN 4560
             ++          P      + + V  G L +   ++     +   W K G+++    + 
Sbjct: 2059 VKR--------AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 2110

Query: 4561 KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
             I       +L IL     D G+Y C A N  G   C A   V+
Sbjct: 2111 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 2154



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 6/131 (4%)

Query: 734  IERTSQHPETLQYI-QQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEA 792
            I++ +      +Y+ + L D  K      +       P   R ++ L E+  G  A F  
Sbjct: 2027 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPL-EVALGHLAKFTC 2085

Query: 793  QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKL 851
            ++   S P +R +W+K GR I  S +  SI +  Y+ SL I+  +  D G YT +A N+ 
Sbjct: 2086 EIQ--SAPNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 2142

Query: 852  GEAISTASIRV 862
            G    TA++ V
Sbjct: 2143 GSVSCTATLTV 2153



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 69  PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
           P PP   Q  +      G  A+F   + G P P +SW +++  L    K    ++ Q  +
Sbjct: 792 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQ--E 849

Query: 129 VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            +LL+ +  P D   YTC A+N YG A  S  +  E
Sbjct: 850 YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 885



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 49/174 (28%), Positives = 76/174 (43%), Gaps = 16/174 (9%)

Query: 1773 KY-VNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQ 1831
            KY ++PE+   +  ++  +  +A T  T  V S A +  E Q ES     ++ E SS   
Sbjct: 1891 KYLISPEEVSYFNVQSRVKYLDA-TPVTKGVAS-AVVSDEKQDESLKPSEEKEESSSESG 1948

Query: 1832 RREDVEVAVNQAPRFITQLNGP--------TKLSEGQSAHYECRIEPYPDPNMRVEWYFN 1883
              E   V + +A     + +GP        T   EG   H    I    + N    WYF 
Sbjct: 1949 TEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVN----WYFE 2004

Query: 1884 GKVLQSGHRYRTSNDFGFAALDILTVYGED-SGEYTCKAINNLGQAVSSIRLNV 1936
             K++ S  +++   D     L I  V  ED  GEY C+A+N+ G+  +S +L V
Sbjct: 2005 NKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 2058



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/90 (30%), Positives = 43/90 (47%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I +K    ++  G  A+F  ++   P  R  WFK G+ +  S+K  I ++   ++L +
Sbjct: 2064 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 2123

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
              TQ  D G YT  A N  G +  +  L V
Sbjct: 2124 LRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+ ++  +    A G  AKF  +++  P     W +    + E +K S+R ++    + +
Sbjct: 2064 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 2123

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            L  Q+   D GEYTC A N+YG   C+
Sbjct: 2124 LRTQVV--DCGEYTCKASNEYGSVSCT 2148



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 43/165 (26%), Positives = 64/165 (38%), Gaps = 9/165 (5%)

Query: 3351 NSGEYECVATNKLGRDSTKANLKCTSKEN---LILDSQLPRGMEGGLEKLQTLEDSMVRR 3407
            N+ E      NKL     K   KC   +N   L++D       +G     + L DS    
Sbjct: 1995 NAKEVNWYFENKLVPSDEK--FKCLQDQNTYTLVIDKVNTEDHQGEYV-CEALNDSGKTA 2051

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
                +   K  APV    +  +E +  G  A F   +     PN++ +W+  G+ +    
Sbjct: 2052 TSAKLTVVKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESD 2108

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            +           LEI  T   D GEY C+A N YG    TA++ V
Sbjct: 2109 KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD--FQIHTFSTKSIL 4468
            P F + +   RV   E  RF     G P P I+W+     I  + D  F     +  +++
Sbjct: 1021 PSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALM 1080

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            +I   + E +  ++  A N  G A C+A L V  K
Sbjct: 1081 LIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPK 1115



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PV    +  LE +  G  A F C ++  + P++   WF  G++I    +          +
Sbjct: 2064 PVIKRKIEPLE-VALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKCSIRSSKYISS 2120

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L+IL T   D G Y CKA+N+ G    T TL V
Sbjct: 2121 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           V   KI +KP++    E A   F+V +S +  P V WF     +  S+KH +++      
Sbjct: 348 VETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHK 406

Query: 323 LRVRNTQKSDSGHYT 337
           L ++N   SD+G YT
Sbjct: 407 LMLQNISPSDAGEYT 421



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 34/145 (23%), Positives = 62/145 (42%), Gaps = 6/145 (4%)

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIK 1985
            + V+S  ++ + ++  ++ S+ +         E+ +  K    +  F+ E  P    P+ 
Sbjct: 1918 KGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLV 1977

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            +    EG  VHL  ++T   +    V WY   + V    +FK   D     L I     E
Sbjct: 1978 DTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE 2033

Query: 2046 D-TGTYMCKATNAVGEAVTTSSVKV 2069
            D  G Y+C+A N  G+  T++ + V
Sbjct: 2034 DHQGEYVCEALNDSGKTATSAKLTV 2058



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 2/125 (1%)

Query: 1278 DTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPV 1337
            +T++ Q     + L D+ +     +  +    AP   R +  +E   G      C +Q  
Sbjct: 2031 NTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA 2090

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             +  +R +WF  G+ I    +          +L++L     D G YTC+A+N+ G    +
Sbjct: 2091 PN--VRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT 2148

Query: 1398 CALRV 1402
              L V
Sbjct: 2149 ATLTV 2153



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/130 (22%), Positives = 57/130 (43%), Gaps = 4/130 (3%)

Query: 3793 IVLESQLPQGMSGEKIKEL--ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850
            +V++    +   GE + E   + G+ + + K   +    P    +I+   V      +F 
Sbjct: 2025 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFT 2084

Query: 3851 CRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910
            C ++    P +R +W++ G+ +    +          SL+IL     D GEY C+A N++
Sbjct: 2085 CEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 2142

Query: 3911 GEDFTKATIS 3920
            G     AT++
Sbjct: 2143 GSVSCTATLT 2152



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 18/168 (10%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            KD+  +    +A +E S+      ++ ++WF+    I+ S + R V    +  L +    
Sbjct: 358  KDVTALENATVA-FEVSV---SHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 413

Query: 3115 TTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174
             +D+G Y+       GQ      LEC  K   +    T  ++NIE + + ++A FEC V 
Sbjct: 414  PSDAGEYTAVV----GQ------LECKAKLFVETLHITKTMKNIE-VPETKTASFECEVS 462

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
              + P M   W  NG  +  S + K V       L I  T   DS EY
Sbjct: 463  HFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEY 507



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            L D+ K    +    V   APV    ++ + VA    A F   +     P +R +W + G
Sbjct: 2044 LNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAG 2101

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
              I  S++ +        +L +      D G YTC+A NE G    ++TL V
Sbjct: 2102 REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYIS-LDMLSLNIQDSGEYTCRAVSATGVAETKA 724
            P ++ +W K G+ I  S +  SI    YIS L++L   + D GEYTC+A +  G     A
Sbjct: 2091 PNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 2149

Query: 725  VLHVT 729
             L VT
Sbjct: 2150 TLTVT 2154



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 4/123 (3%)

Query: 1147 HRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGD 1206
            H+G Y     + +S       ++  + ++ PV  + +  P  V+ G      C ++    
Sbjct: 2035 HQGEYV-CEALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSA-- 2090

Query: 1207 PTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
            P +R +WF  GR +    +          +L+I+     D GEYT +A N  GS   +A 
Sbjct: 2091 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 2150

Query: 1267 VRV 1269
            + V
Sbjct: 2151 LTV 2153



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P  K  I + + +  G  A F   ++   +  +R +W K GR +  S + +   +    +
Sbjct: 2064 PVIKRKI-EPLEVALGHLAKFTCEIQSAPN--VRFQWFKAGREIYESDKCSIRSSKYISS 2120

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I    V D G YTC+A N  G  + +A LT+
Sbjct: 2121 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 42/175 (24%), Positives = 69/175 (39%), Gaps = 13/175 (7%)

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           + +K  +D    E     F+  V+    P V WF  + +I+    H+ LV+E   H LM+
Sbjct: 352 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLML 409

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
            N++ SD+G  T V     G+   +C+  +     V      +    + V E +      
Sbjct: 410 QNISPSDAGEYTAVV----GQ--LECKAKLF----VETLHITKTMKNIEVPETKTASFEC 459

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
                  P + W K+GV I  + + +I   G    L I      D+A Y     N
Sbjct: 460 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 513



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 6/97 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P   TP+ D +S +EG   H    +     +   V W  + + V +  +     +     
Sbjct: 1970 PMIHTPLVDTVS-EEGDIVHLTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYT 2024

Query: 969  LTIKSVTVHD-AGHYTCRAYNAIGQATTSANLTIVTK 1004
            L I  V   D  G Y C A N  G+  TSA LT+V +
Sbjct: 2025 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 2061



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            G  A F C+++    PN+R +++  G+ +  + +  I       SL+I      D GEY+
Sbjct: 2078 GHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 2135

Query: 2317 VKAINALGHCTSAISMTVT 2335
             KA N  G  +   ++TVT
Sbjct: 2136 CKASNEYGSVSCTATLTVT 2154



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 10/96 (10%)

Query: 771 QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-S 829
           +F + ++D+  L++ R A FE +   VS+P + V+W KD + +  + RI  I    YV  
Sbjct: 615 EFRKHIKDIKVLEKKR-AMFECE---VSEPDITVQWMKDDQELQITDRI-KIQKEKYVHR 669

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           L I   R  DAG YTV A    G  +STA + V  R
Sbjct: 670 LLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 701



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERD-SGI 2983
            EG ++HL   +    +    + WYF  K++    +FK   D    TL +  V   D  G 
Sbjct: 1983 EGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 2038

Query: 2984 YTCKAYNKRGEAFTSS 2999
            Y C+A N  G+  TS+
Sbjct: 2039 YVCEALNDSGKTATSA 2054



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 4/125 (3%)

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
            TE +  +   + + D+ +  T  ++ + ++A AP   +  +  +V  G + +F C +   
Sbjct: 2032 TEDHQGEYVCEALNDSGKTATSAKLTVVKRA-APVIKRKIEPLEVALGHLAKFTCEIQSA 2090

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P     WF   R+I +  + K  +  S    +L I    + D G  TC A N+ G  +  
Sbjct: 2091 PNVRFQWFKAGREIYE--SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT 2148

Query: 478  CRLNV 482
              L V
Sbjct: 2149 ATLTV 2153



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P   + I+  EV  GH       +     P +R +W+  GR + +  +          +L
Sbjct: 2064 PVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSL 2121

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +IL     D G Y CKA+N  G    T+++ V
Sbjct: 2122 EILRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LDITHTYEEDSGIYTCKAT 2851
            F C ++ +  P ++ +WF   + +    +  S     Y+S L+I  T   D G YTCKA+
Sbjct: 2083 FTCEIQSA--PNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKAS 2139

Query: 2852 NSKGSATTSGSLRCT 2866
            N  GS + + +L  T
Sbjct: 2140 NEYGSVSCTATLTVT 2154



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 46/180 (25%), Positives = 69/180 (38%), Gaps = 16/180 (8%)

Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
           K  ++ +V E K   F+C V+    P + W  N  +I      KI+V +   H L+I N 
Sbjct: 442 KTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVV-QGKLHQLIIMNT 499

Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARA 514
           +  DS            E  F C  + +     V P  +      +N  E + +      
Sbjct: 500 STEDSA-----------EYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEV-T 547

Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
           V        W K+GV I    + ++ T     +L+I      DAA Y   A   A STAT
Sbjct: 548 VNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA-GKATSTAT 606



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/90 (26%), Positives = 37/90 (41%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P+  +K++P  V     A+F  E    P    +W++    I  S    I +    S L I
Sbjct: 2064 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 2123

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +  V D   +   A N  G+  C+A L V
Sbjct: 2124 LRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 64/331 (19%), Positives = 127/331 (38%), Gaps = 35/331 (10%)

Query: 79  KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
           K+    +     FE  +  +  PV  W  K   +   +K+ +    +     L+++ I P
Sbjct: 358 KDVTALENATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVSERKVH--KLMLQNISP 414

Query: 139 GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
            D GEYT       G+  C   +  E                   + +E     T  +  
Sbjct: 415 SDAGEYTAVV----GQLECKAKLFVE-----------TLHITKTMKNIEVPETKTASFEC 459

Query: 199 EQSR-QTQKVAYTNGTDHSSTDDFKV---DTFEYRLLREVSFRESITKRYVGESDVQIST 254
           E S      +   NG +   ++ FK+         ++   S  +S    +V  +D Q+S 
Sbjct: 460 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND-QVSA 518

Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            +      V+P  I    ++   +E     F+V ++        W KNG  + +++K ++
Sbjct: 519 TLT-----VTPIMITSMLKDINAEEKDTITFEVTVNYEGIS-YKWLKNGVEIKSTDKCQM 572

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            T     +L +RN    D+  YT +A    G   ++  L VE+    + +  +   + + 
Sbjct: 573 RTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHIKDIKVLEK 628

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTE 405
           ++   E   E+SE  +  Q++K  Q+  +T+
Sbjct: 629 KRAMFE--CEVSEPDITVQWMKDDQELQITD 657



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
           +K++   E     FE  +     P+M   WLKNG  IE S +F  + +     L +++ +
Sbjct: 444 MKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 500

Query: 703 IQDSGEYTCRAVSATGVAETKAVLHVTP 730
            +DS EYT       G  +  A L VTP
Sbjct: 501 TEDSAEYT----FVCGNDQVSATLTVTP 524



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 7/89 (7%)

Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIAS 1107
            PLK  N ++EG  A  E +V    D+T +V+WY N +QI   +R+Q         L I  
Sbjct: 6    PLKDVN-VIEGTKAVLECKVSVP-DVT-SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINR 62

Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
              A D G Y ++     G  + + +++VE
Sbjct: 63   THASDEGPYKLI----VGRVETNCNLSVE 87



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/179 (22%), Positives = 67/179 (37%), Gaps = 13/179 (7%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
           +D +V EG     +C+V+      V W++ND QI+ D   + +V +     L+I     S
Sbjct: 8   KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV-KGTKQRLVINRTHAS 66

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           D G    +     G     C L+V   E++   K +     L   E + VV       + 
Sbjct: 67  DEGPYKLIV----GRVETNCNLSV---EKI---KIIRGLRDLTCTETQNVVFEVELSHSG 116

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA-QNVAGSTATRA 576
              + W      I P+ + +I   G    L +      D   Y   A +N+     T A
Sbjct: 117 ID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVA 174



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/92 (28%), Positives = 42/92 (45%)

Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
           +GE   +++T    +   V   KI +  +N  + E  DA F V+L+      V W KNG 
Sbjct: 242 IGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV 301

Query: 305 RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            L ++ K+ I       +LR++N    D   Y
Sbjct: 302 VLESNEKYAISVKGTIYSLRIKNCAIVDESVY 333



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 56/262 (21%), Positives = 107/262 (40%), Gaps = 18/262 (6%)

Query: 1410 LESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLE 1469
            +ES++    E++ Y    SR K  D    +  +    V+  K  E++   +    E   E
Sbjct: 1888 VESKYLISPEEVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLKPSEEKE-ESSSE 1946

Query: 1470 PVTD--SNLKVEWFKNGQPVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVN--- 1523
              T+  + +K++  + G     G     P+ D      DI+ L    + I   + VN   
Sbjct: 1947 SGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLT---TSITNAKEVNWYF 2003

Query: 1524 ---LVGTDEVSCRLTCRSTTDIVR---STQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
               LV +DE    L  ++T  +V    +T++  G    + L D  K   +  +  V   A
Sbjct: 2004 ENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 2063

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P+    ++ +E+  G  A F   +   S   ++ +W+   + +    + +  ++    +L
Sbjct: 2064 PVIKRKIEPLEVALGHLAKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSL 2121

Query: 1638 DIMSCLPEDSGTYTCRAINALG 1659
            +I+     D G YTC+A N  G
Sbjct: 2122 EILRTQVVDCGEYTCKASNEYG 2143



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 19/163 (11%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSG 3119
            +E Q   +E  L  +G   + + W +  K I+ S + + + A G +  L +L     D G
Sbjct: 101  TETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEG 156

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             Y+  A       +++V    + K    +            + + Q A FEC V    +P
Sbjct: 157  KYTFYAGENITSGKLTVAGGAISKPLTDQT-----------VAESQEAVFECEVA---NP 202

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            D K EW  +G+ +  +  I++ SD     L IA T+  D GEY
Sbjct: 203  DSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY 245



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 8/94 (8%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            F  H+K   K++E +    E +V   ++P++ ++W K+   L    R+K   +  +  L 
Sbjct: 616  FRKHIKDI-KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLL 671

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            I S R  D+G YT  A    G  VSTA + +E R
Sbjct: 672  IPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 701



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            K++E + A FE  V   S+  +TV+W  + +++   +RI+   +     L I S R  D+
Sbjct: 624  KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 680

Query: 1114 GVYTVVARNAAGEAQL 1129
            G YTVVA      A+L
Sbjct: 681  GKYTVVAGGNVSTAKL 696



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAED-SGVYTVVARNAAGEAQLSASMTV 1135
            V WYF  K + S  + +   D     L I  V  ED  G Y   A N +G+   SA +TV
Sbjct: 1999 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 2058

Query: 1136 ETRSS 1140
              R++
Sbjct: 2059 VKRAA 2063



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/68 (29%), Positives = 34/68 (50%)

Query: 2667 EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            E ++ PN++ +WFK G  +    +        + +L I   +  D G YTCKA+N  G  
Sbjct: 2086 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 2145

Query: 2727 VSTASIKI 2734
              TA++ +
Sbjct: 2146 SCTATLTV 2153



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 16/179 (8%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  P   T++ KDI +  E     +E ++   G   +  +W  NG  I+++ + +     
Sbjct: 521  TVTPIMITSMLKDI-NAEEKDTITFEVTVNYEG---ISYKWLKNGVEIKSTDKCQMRTKK 576

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L I      D+  Y+  A      A + V+   ++        F  HI++I+ L+ 
Sbjct: 577  LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIE--------FRKHIKDIKVLEK 628

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             + A FEC V    +PD+ ++W  + Q ++ + RIK   +     L I  T+  D+G+Y
Sbjct: 629  -KRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKY 683



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/137 (21%), Positives = 59/137 (43%), Gaps = 10/137 (7%)

Query: 1270 IERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVH 1329
            ++ S+   ++ +E   E++  ++        ++ED  ++  P     L +  + EG  VH
Sbjct: 1934 LKPSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTP-----LVDTVSEEGDIVH 1988

Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED-SGVYTCQAT 1388
            L   +         V W+   K + +  +F+   + +   L +  V  ED  G Y C+A 
Sbjct: 1989 LTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 2044

Query: 1389 NQLGEAVTSCALRVIAK 1405
            N  G+  TS  L V+ +
Sbjct: 2045 NDSGKTATSAKLTVVKR 2061



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 7/140 (5%)

Query: 3662 PSHFKSGTESIQKLEETLH-KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVE 3720
            PS  K  + S    EE    K +E      K + P     + D +   EG  VH    + 
Sbjct: 1936 PSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVS-EEGDIVHLTTSIT 1994

Query: 3721 PVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD-AGEYTCRATNKWGSA 3779
               +    ++W+   +   +  +   L D     L ID +   D  GEY C A N  G  
Sbjct: 1995 NAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKT 2050

Query: 3780 TTTAKITCSAKRDIVLESQL 3799
             T+AK+T   +   V++ ++
Sbjct: 2051 ATSAKLTVVKRAAPVIKRKI 2070



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/69 (24%), Positives = 37/69 (53%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E ++ P+++ +W+  G+ + +  +  + S     +L+++     D G YTCKA N+ G  
Sbjct: 2086 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 2145

Query: 2996 FTSSTVYCT 3004
              ++T+  T
Sbjct: 2146 SCTATLTVT 2154



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 8/102 (7%)

Query: 1688 LNQL-EDTSKYQRHSAQD----EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL 1742
            LN + +D  KY  ++ ++    ++       + P+ D  VAE+Q A FE     V +P  
Sbjct: 148  LNMMKDDEGKYTFYAGENITSGKLTVAGGAISKPLTDQTVAESQEAVFECE---VANPDS 204

Query: 1743 RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYT 1784
            + EWLR+G  +  +N + +  D     L +     +D G YT
Sbjct: 205  KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYT 246



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P    PL    + EG  +H  T I    +    + W    + + +  +F  +      +L
Sbjct: 1970 PMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTL 2025

Query: 697  DMLSLNIQD-SGEYTCRAVSATGVAETKAVLHVTPRA 732
             +  +N +D  GEY C A++ +G   T A L V  RA
Sbjct: 2026 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 2062



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 1/116 (0%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF-EARVEPQSDLTMTVEW 1079
            +Y+ +A   S +T    K+T   R    +K   + +E    H  +   E QS   +  +W
Sbjct: 2038 EYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQW 2097

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +  G++I  +++          +L+I   +  D G YT  A N  G    +A++TV
Sbjct: 2098 FKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           +F K  +D  V E K   F+C V+  P   V W  +D++++     KI   E   H L+I
Sbjct: 615 EFRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQ-KEKYVHRLLI 672

Query: 453 TNVTLSDSGVVTCVA-RNKSGETAF----QCRLNVIEKEQVVAPK 492
            +  +SD+G  T VA  N S    F      R+  I+KE  V  K
Sbjct: 673 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 717



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I  L ++ C E  N+ FE  +  S    + + W F +K +   ++YK         L + 
Sbjct: 92   IRGLRDLTCTETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVL 148

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            +  ++D G YT  A    G   TSG L   G
Sbjct: 149  NMMKDDEGKYTFYA----GENITSGKLTVAG 175



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 5/98 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P+   P+ D    E    H    +    +    V W      + +  +   + D     L
Sbjct: 1970 PMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTL 2025

Query: 1771 NMKYVNPED-SGTYTCRAINELGEAVTSSTLFVQSKAS 1807
             +  VN ED  G Y C A+N+ G+  TS+ L V  +A+
Sbjct: 2026 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 2063



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA-MNFGWVYPEDSGEYLCRA 4050
            KF C++     PN++ +WF  G+ +   ++ + I    Y++ +        D GEY C+A
Sbjct: 2082 KFTCEIQSA--PNVRFQWFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEYTCKA 2138

Query: 4051 TNLYGMDETKAVIKTT 4066
            +N YG     A +  T
Sbjct: 2139 SNEYGSVSCTATLTVT 2154



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            +   TV ES+   FEC V    +P  + EW R+GK LP  +  R+  D     L I    
Sbjct: 182  LTDQTVAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATK 238

Query: 3896 AEDSGEY 3902
             +D GEY
Sbjct: 239  LDDIGEY 245



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            ++E Q A +EC +    +P+ + EW  +GK L   +  R+ +D     L I     +D G
Sbjct: 187  VAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIG 243

Query: 1916 EYTCKAINNLGQA---VSSIRLNVQSKESIIRDSQ 1947
            EYT K   +   A   V ++++    K   + ++Q
Sbjct: 244  EYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQ 278



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDI-LYCYEENSGEYECVATNKLGRDSTKANL 3372
            +V W++  K +P   +++   D     L I     E++ GEY C A N  G+ +T A L
Sbjct: 1998 EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 2056



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 6/82 (7%)

Query: 1459 GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDLIAEDSGIY 1517
            G    F C+++     N++ +WFK G+ +    +   I    Y++ L+I+     D G Y
Sbjct: 2078 GHLAKFTCEIQSAP--NVRFQWFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEY 2134

Query: 1518 TCRAVNLVGTDEVSCRLTCRST 1539
            TC+A N  G+  VSC  T   T
Sbjct: 2135 TCKASNEYGS--VSCTATLTVT 2154



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 3575 AHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
            A F C +   +  ++R +WF  G+ +    +    +      LEI      D G YTCKA
Sbjct: 2081 AKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 2138

Query: 3635 TNRHGEATVSCKLQV 3649
            +N +G  + +  L V
Sbjct: 2139 SNEYGSVSCTATLTV 2153



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V R  PV  + ++ ++ +  G  A F C +     P ++ +WF+  + I +S + +    
Sbjct: 2059 VKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSS 2115

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                S+ I   +  D G Y C+ASN  G
Sbjct: 2116 KYISSLEILRTQVVDCGEYTCKASNEYG 2143



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 910 EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
           EF+  IKD I + E   A FE     + +  + V+W+KD + ++ + RI          L
Sbjct: 615 EFRKHIKD-IKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRL 670

Query: 970 TIKSVTVHDAGHYTCRAYNAIGQA 993
            I S  + DAG YT  A   +  A
Sbjct: 671 LIPSTRMSDAGKYTVVAGGNVSTA 694



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 3/95 (3%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP      ++   ++G  A+F+ ++ G    V SW  K   +     + M   E T    
Sbjct: 900 PPAIITPLQDTVTSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFEDT--YQ 956

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           L I +  P DEG YT  A N  G+   +  +  EG
Sbjct: 957 LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEG 991



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 5/93 (5%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
            +    P+  T L +   +EG   H    +    +    V WY  NK + S  +F    + 
Sbjct: 1965 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQ 2020

Query: 1633 GFVALDIMSCLPED-SGTYTCRAINALGEAVTS 1664
                L I     ED  G Y C A+N  G+  TS
Sbjct: 2021 NTYTLVIDKVNTEDHQGEYVCEALNDSGKTATS 2053



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I +  P+   PL +     EG  +HL   +    +    V W+   + V    +FK   D
Sbjct: 1965 IKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQD 2019

Query: 1232 FGFVALDIIHATSAD-TGEYTVRAVNHLGSAHTSAIVRVIERS 1273
                 L I    + D  GEY   A+N  G   TSA + V++R+
Sbjct: 2020 QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 2062



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 774 RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIM 833
           +PL D   + E + A FE +   V++P  + EW +DG+ +  ++ I S  +     L I 
Sbjct: 180 KPLTDQ-TVAESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIA 235

Query: 834 HLRAEDAGSYTVR-AVNKLGEAISTASIRV 862
             + +D G YT + A +K    +   ++++
Sbjct: 236 ATKLDDIGEYTYKVATSKTSAKLKVEAVKI 265



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 2245 VTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDI 2304
            +T+      V E KTA FEC+V   + P++ ++   NG  ++ + +F I        L I
Sbjct: 440  ITKTMKNIEVPETKTASFECEVSHFNVPSMWLK---NGVEIEMSEKFKIVVQGKLHQLII 496

Query: 2305 QHCVPEDAGEYS 2316
             +   ED+ EY+
Sbjct: 497  MNTSTEDSAEYT 508



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/64 (29%), Positives = 31/64 (48%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P+++ +WF  G+++    +        I  L+IL     + GEY C A+N+ G  S  A 
Sbjct: 2091 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 2150

Query: 3372 LKCT 3375
            L  T
Sbjct: 2151 LTVT 2154


>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
            protein.
          Length = 1914

 Score =  167 bits (407), Expect = 7e-40
 Identities = 116/431 (26%), Positives = 185/431 (42%), Gaps = 13/431 (3%)

Query: 4389 EIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN 4448
            ++  KA  +   +EG  + S  P F  K Q   V E++  +F  E  G P P + W+ E 
Sbjct: 393  DVVSKAANRRIPMEGQ-RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEG 451

Query: 4449 FPIKNSP-DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
             P++      +++  +    L + +    DS  ++  A N  G   CS  L VE      
Sbjct: 452  TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME 511

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567
                V PSF+   ++  V  GQ   L   V GT    + WL NG+ +Q   R+    E G
Sbjct: 512  ----VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTC--EAG 564

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK---PQTKAANAPPE 4624
               L I +A P+D G Y C+A N+ G+  C A   V    +  K +   P   +    P 
Sbjct: 565  VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
             ++ L D  V +G  +  + ++ G P P V W      I+ S+ F   +   +++L I E
Sbjct: 625  FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQE 684

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
             FPED G Y C A+NSAG V   A L V +P        ++  R +    GQ       I
Sbjct: 685  VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744

Query: 4745 TSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                 PT+ WLR+G AL  +T  F+++   +   L++        G +        G+  
Sbjct: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804

Query: 4804 TSAKLVVKSKT 4814
                L++++ +
Sbjct: 805  CQVSLMLQNSS 815



 Score =  109 bits (262), Expect = 2e-22
 Identities = 80/334 (23%), Positives = 136/334 (40%), Gaps = 19/334 (5%)

Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
           G+     + +++R       P  +   ++  + EG D   Q  + G P PR+TW  NGQ 
Sbjct: 494 GQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553

Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
           +  +             L +++    D G YT LAEN  G +  S ++ V     S    
Sbjct: 554 IQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS---- 606

Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           ++S+Y+                K  AP F++   D  V +G       +V+G P PEV W
Sbjct: 607 RKSEYLLPVAP----------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             N  +I++  +          H+L I  V   D+G  TC A N +GE   Q  L V E 
Sbjct: 657 LHNGNEIQESEDFHF-EQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715

Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGG 544
                P F+ +  ++    G+ V+++    G P P + W +DG  +  +     +  +  
Sbjct: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775

Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             TL + + +   A  Y+   +N  G  + +  L
Sbjct: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809



 Score =  107 bits (258), Expect = 7e-22
 Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 14/235 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-G 3476
            +AP F +P  N+  ++EG  A FE R+    +P  +V W+ NG+ + +G RF   C   G
Sbjct: 31   EAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 3477 FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIA 3536
               L I   + ED G+Y C A N  G    T  + V+G        QL + +   + K  
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPV---VSKTL 140

Query: 3537 ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
                 +  V+T  P      PP+F T    +++ E     F C++        +V W   
Sbjct: 141  GDRFSASAVET-RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
              PL   +RV      G  +LEI GV Q D G+YTC   N  G+A++S +L ++G
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score =  104 bits (250), Expect = 7e-21
 Identities = 88/328 (26%), Positives = 132/328 (40%), Gaps = 46/328 (14%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEIITTHNHTTLR 324
           PK   KP++ +++E    +F+ ++SG P+P V WF  G  +       E+        L 
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +   +  DSG Y+  A N  G +  S  L VE                         R+ 
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVE-------------------------RLA 508

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
           + E  +AP F  V +D  V EG+     C V G P P +TW +N + I+  Y       E
Sbjct: 509 VME--VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTC--E 562

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE--------------QVVA 490
           +G   L I +    D G  TC+A N  G+ +    + V EK+              +  A
Sbjct: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P F++  S L V +G  V +  +  G P P + W  +G  I  + +      G   +L I
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 682

Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARL 578
                 D   Y C A N AG   T+A L
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score =  102 bits (244), Expect = 4e-20
 Identities = 76/245 (31%), Positives = 112/245 (45%), Gaps = 10/245 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDF 1765
            +T+AP F +P +++ + E   A FE R+   G P+ +V W RNG PI +  R L      
Sbjct: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G  +L +  V+ ED G YTC A N  G    +  L V+   + QL     S  + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS--KTLGDRF 144

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             +S  + R  +       P+F T+L G   + EGQ   + C+I   P P  +V W     
Sbjct: 145  SASAVETRPSIWGEC--PPKFATKL-GRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNV 199

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
             LQ   R   S   G   L+I  V  +D G YTC  +N  G+A  S  L++Q  +S  R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 1946 SQHES 1950
               E+
Sbjct: 260  FVRET 264



 Score =  100 bits (240), Expect = 1e-19
 Identities = 68/246 (27%), Positives = 114/246 (46%), Gaps = 5/246 (2%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           +   ++ ++ + +      S+     P     PRN  ++EGA A+F+ ++ G P P+VTW
Sbjct: 7   VASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTW 66

Query: 300 FKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-S 357
            +NGQ + +  +  +      T +L +    + D G YT  A N +G    +  L VE S
Sbjct: 67  HRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126

Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
             +   Q   S+ + D       E          P+F        V EG+M RF C++TG
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNE-SGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
           RP P+VTW   +  ++   + ++ V+E +G   L I  V   D GV TC+  N SG+ + 
Sbjct: 187 RPQPQVTWLKGNVPLQP--SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244

Query: 477 QCRLNV 482
              L++
Sbjct: 245 SAELSI 250



 Score =  100 bits (240), Expect = 1e-19
 Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 8/219 (3%)

Query: 4404 PVKPSKP--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            PV PSKP  PIF + +   +V +  Q    V+  G P P + W      I+ S DF    
Sbjct: 614  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
              T+  L I++VF ED+  +   A N  G  +  A L V+E    G      P F    +
Sbjct: 674  RGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH-DG----TQPWFISKPR 728

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQD 4580
            +V  + GQ V +   + G     V+WL++GK +  D  + ++L+ +  +TL++ +  P  
Sbjct: 729  SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +G+YE +  N  GE  C    ++   + +  P+ +  A+
Sbjct: 789  AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPAS 827



 Score =  100 bits (239), Expect = 1e-19
 Identities = 107/361 (29%), Positives = 152/361 (42%), Gaps = 62/361 (17%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH-DFGYV 1502
            P+F ++P+S E V E Q V F C++  +     +V WF  G PV        ++ D G  
Sbjct: 414  PKFESKPQSQE-VKENQTVKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L ++     DSG Y+C A N  G  +VSC  T +              +E++ V+E   
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQG--QVSCSWTLQ--------------VERLAVME--- 511

Query: 1563 KYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKS 1622
                          AP  ++ LK+  + EGQ   F  +         ++ W  N +P++ 
Sbjct: 512  -------------VAPSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQY 556

Query: 1623 GSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHE 1682
                 E    G   L I   LPED GTYTC A NALG+   S    VH KKS     + E
Sbjct: 557  ARSTCEA---GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS---SRKSE 610

Query: 1683 GALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL 1742
              LP        SK             AP+F   + D++V +        ++   G+P  
Sbjct: 611  YLLP-----VAPSK-----------PTAPIFLQGLSDLKVMDGSQVTMTVQV--SGNPPP 652

Query: 1743 RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             V WL NG  I+ S            +L ++ V PED+GTYTC A N  GE  T + L V
Sbjct: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712

Query: 1803 Q 1803
            Q
Sbjct: 713  Q 713



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 19/225 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P+F L  +N+ +  G   + + +V G     V W +NG+ +    R  +     GT++L+
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP---------------QTK 4617
            I   + +D GKY C A N +G  +   E  V     K   +P               +T+
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4618 AA---NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             +     PP+    L   +V EGQ   FSCKI G+P P V W KG+  ++PS    +S  
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
                 L I     +D G Y C+  N +G+ +++A+L +   D A+
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 167/703 (23%), Positives = 277/703 (39%), Gaps = 94/703 (13%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            FI    N+  KEG    FE  V    +P  ++ W  N +P+ SG R+          SL 
Sbjct: 35   FILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I   +EED G YTC+ATN  G+   +  L   G     F  Q  Q        ++   + 
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSAS- 147

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
             A   RPS+   E P P++   +     + EGQ+     ++  +  P  ++ W      L
Sbjct: 148  -AVETRPSIWG-ECP-PKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPL 201

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD----NLI 3010
            +  +R  ++   G   L++  V + D G+YTC   N  G+A  S+ +     D    + +
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261

Query: 3011 ERTQHPKGTEGLE---------KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDIS 3061
              T+        E         K+ +LE + + +    P    G PP             
Sbjct: 262  RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRG-GSPP--WAANSQPQPPR 318

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK-----TT 3116
            E ++   + S   T  Q+ V++   +  T++A+       A G+ VL   G +       
Sbjct: 319  ESKLESCKDS-PRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP 377

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQK----PRFTTHIQNIEGLKDGQSAHFECT 3172
               T+  R      Q  +S         +GQ+    P+F +  Q+ E +K+ Q+  F C 
Sbjct: 378  RPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE-VKENQTVKFRCE 436

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHST-RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            V  +  P+  + W+  G P+R     I+   D G   L +   +  DSG Y C A N  G
Sbjct: 437  VSGIPKPE--VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494

Query: 3232 EDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDV 3291
            +      ++C         +LQ + LA            +  PS        F + ++D 
Sbjct: 495  Q------VSCSW-------TLQVERLA----------VMEVAPS--------FSSVLKDC 523

Query: 3292 TKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEEN 3351
              ++EGQ   F  +      P  ++ W  NG+ + +    R+  + G+  L I     E+
Sbjct: 524  A-VIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPED 577

Query: 3352 SGEYECVATNKLGRDSTKA----NLKCTSKENLILDSQLPRGMEG-----GLEKLQTLED 3402
             G Y C+A N LG+ S  A    + K +S+++  L    P          GL  L+ ++ 
Sbjct: 578  HGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDG 637

Query: 3403 SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLT 3445
            S V    T   +  G  P   + L N   ++E E+ HFE R T
Sbjct: 638  SQV----TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 18/246 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-VKTINDFGFVI 3616
            P F   P +L + E ++A FE R+    +   +V W  NG+P+ +G R +      G   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V++ D G YTC+ATN  G   V+ +L V+G        QL     S T   +   
Sbjct: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSA 146

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
              +  R  I  E     PP+F  ++   + V EG    F C++   G P  ++ W     
Sbjct: 147  SAVETRPSIWGEC----PPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNV 199

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC----SAKRD 3792
            P    +RV      G   L+I  +   D G YTC   N  G A+ +A+++     SA R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 3793 IVLESQ 3798
             V E++
Sbjct: 260  FVRETK 265



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 64/224 (28%), Positives = 96/224 (42%), Gaps = 25/224 (11%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F   +K+  V EG    L+ ++     P  R+ W  NG+P+Q     ++T + G   L
Sbjct: 514  PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 568

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             I  A  ED GTY C A NA+G+   ++ V V  K                +   K E  
Sbjct: 569  HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK----------------KSSRKSEYL 612

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
             P+   +P   P+FL  L+   +LK  D +     V+   +P   + W HNG +I+    
Sbjct: 613  LPVAPSKP-TAPIFLQGLS---DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +         +L I   + ED+GTY C+A N  GE      L V
Sbjct: 669  FHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 16/225 (7%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGFIALDIDYIYA 3762
            N+ + EG    F+ RV   G P  ++ W  NG+P  +G R +      G  +L I  ++ 
Sbjct: 41   NLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS-DAPK 3821
             D G+YTC ATN  G+   T ++T           QL Q +  + + +    R S  A +
Sbjct: 99   EDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGD----RFSASAVE 150

Query: 3822 EEPIV--STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              P +    PPKF T++    V+E +  RF C++  +  P  ++ W +    L    R  
Sbjct: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVS 208

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
                 G   L+I  V  +D G Y C  VN  G+    A +S + L
Sbjct: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 18/242 (7%)

Query: 2899 RRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS 2958
            R  S+P TE   P +I+P      + EG     EG+V  +  P+ ++ W+ NG+ +  G 
Sbjct: 23   RVDSMPLTE--APAFILP-PRNLCIKEGATAKFEGRV--RGYPEPQVTWHRNGQPITSGG 77

Query: 2959 RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK 3017
            RF L     G  +L +  V+E D G YTC+A N  G      TV  T + +  ++   P 
Sbjct: 78   RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPV 135

Query: 3018 GTEGLEKIQNLEDSLRKEPGQQPDDDTGR-PPEFTTVFKDIVDISEGQIAHYEASLIPTG 3076
             ++       L D       +      G  PP+F T    +V + EGQ+  +   +  TG
Sbjct: 136  VSK------TLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKI--TG 186

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
                 + W      ++ S R+      GM VLEI G    D G Y+C   N  G+A +S 
Sbjct: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246

Query: 3137 KL 3138
            +L
Sbjct: 247  EL 248



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 70/260 (26%), Positives = 115/260 (44%), Gaps = 36/260 (13%)

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            EKR + +G    P+F    Q+V+V  G+ + L  +V+   P  + W  NGK ++   +  
Sbjct: 1088 EKRSESQG--TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFI 1144

Query: 4562 ILEEDGTYTLLILE-AYPQDSGKYECVAINSAGEARCDAECVV-SLPATKDKPKPQTK-- 4617
            IL ++G+   + +E A P+D G Y+CVA N AG+A C  +  V   PA+++   P+ K  
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204

Query: 4618 ----------------------AANAPP------EIIEPLKDKIVAEGQAIEFSCKIVGK 4649
                                  A   PP      +II+  +D+ V  G+++E   K+ G 
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
               T  W K  K I+ S++ ++  + +   L I  A  E  G Y  +  N  G       
Sbjct: 1265 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1324

Query: 4710 LKVT-QPDQADNLPALTPLR 4728
            L V  +PD     P  + +R
Sbjct: 1325 LTVVDKPDPPAGTPCASDIR 1344



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 62/249 (24%), Positives = 111/249 (44%), Gaps = 12/249 (4%)

Query: 617 HVERARPYIPPGEEDRV--YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLK 674
           H+ +    + P   D +     P FI+P +++   EG    FE R+   G P  ++ W +
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHR 68

Query: 675 NGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
           NGQ I +  RF       G  SL + +++ +D G+YTC A + +G  +    + +T   +
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV--TVELTVEGS 126

Query: 734 IERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQ 793
             +    P   + +      S  + + SI  +    P+F   L  +  ++EG+   F  +
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECP--PKFATKLGRV-VVKEGQMGRFSCK 183

Query: 794 LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           +T    P  +V W K   P+  S+R++     G   L I  +  +D G YT   VN  G+
Sbjct: 184 IT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241

Query: 854 AISTASIRV 862
           A  +A + +
Sbjct: 242 ASMSAELSI 250



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 65/228 (28%), Positives = 99/228 (43%), Gaps = 14/228 (6%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            +T  P F+  P+++  + EG    FE ++    +   +V W +NGQP+T G RF      
Sbjct: 29   LTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGI 85

Query: 1500 -GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI-QV 1557
             G  +L I  +  ED G YTC A N  G  +V+  LT         S   + G   + + 
Sbjct: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG------SFAKQLGQPVVSKT 139

Query: 1558 LEDRSKYHRTDMVDEVTTQAPI-CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            L DR      +    +  + P    T L  V +KEGQ   F  ++        +V W   
Sbjct: 140  LGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            N PL+  +R + +   G   L+I     +D G YTC  +N  G+A  S
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 15/244 (6%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF- 964
            T+ P F  P ++ + IKEG  A FE R+   G    +V W ++G+P+ +  R        
Sbjct: 30   TEAPAFILPPRN-LCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
            G  +L I +V   D G YTC A N  G    +  LT+  +     +   P   + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRF 144

Query: 1025 DASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEWYFN 1082
             AS  +  T   +     P+F   L G   + EGQ   F  ++   PQ  +T    W   
Sbjct: 145  SAS--AVETRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVT----WLKG 197

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
               +  + R+      G   L+I  V  +D GVYT +  N +G+A +SA ++++   S +
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257

Query: 1143 TSSI 1146
             S +
Sbjct: 258  RSFV 261



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 39/107 (36%), Positives = 57/107 (53%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            E +   +  + P F K  +D +V EG   RFDC++ G P PEV WF +D+ IR+  + +I
Sbjct: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
              +E GN +L+I++V   D    TC A N  GE      L V   E+
Sbjct: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 80/317 (25%), Positives = 135/317 (42%), Gaps = 33/317 (10%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA-FGMVVLEILGTKTTD 3117
            ++ E Q   +   +  +G     + WF  G  +        VY   G   L +L  +T D
Sbjct: 424  EVKENQTVKFRCEV--SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            SGTYSC A+N  GQ   S  L+    +  +  P F++ +++   + +GQ    +C+V   
Sbjct: 482  SGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDC-AVIEGQDFVLQCSVRGT 540

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P  +I W  NGQP++++   ++  + G   L I      D G Y C A N  G+    
Sbjct: 541  PVP--RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCS 595

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +  + K      S + + L  +             PS P+A  P F+  + D+ K+++
Sbjct: 596  AWVTVHEK----KSSRKSEYLLPV------------APSKPTA--PIFLQGLSDL-KVMD 636

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV-ILDILYCYEENSGEY 3355
            G       ++    +P  +V W +NG ++     +  F   G    L I   + E++G Y
Sbjct: 637  GSQVTMTVQV--SGNPPPEVIWLHNGNEIQESEDFH-FEQRGTQHSLWIQEVFPEDTGTY 693

Query: 3356 ECVATNKLGRDSTKANL 3372
             C A N  G   T+A L
Sbjct: 694  TCEAWNSAGEVRTQAVL 710



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 11/215 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGI 2714
            EG     E +V    +P  ++ W +NG  +T+G R        G  +L I+++  +D G 
Sbjct: 46   EGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2715 YTCKATNLLGEAVSTASIKIEDRHWL-LGESLHPDSL-DRIGALXXXXXXXXXXXXXXXX 2772
            YTC+ATN  G    T  + +E      LG+ +   +L DR  A                 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA----SAVETRPSIWGEC 159

Query: 2773 XXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS 2832
               F + L  +V KEG    F C +     P  ++ W   N PL    R   +       
Sbjct: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQV 217

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            L+I    ++D G+YTC   N  G A+ S  L   G
Sbjct: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 12/194 (6%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGE 4045
            E  T KFE ++   G P  +V W  NG+P+    RF       G  ++    V+ ED G+
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 4046 YLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEES 4105
            Y C ATN  G  +    +   G     +  QL + + S        AS   T   +  E 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE- 158

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGM 4164
               CPP F +    V V+EG+  RF C++TG P+P+V WL     +   +R  ++  +GM
Sbjct: 159  ---CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGM 215

Query: 4165 YHFDIPKTRQYDTG 4178
               +I    Q D G
Sbjct: 216  QVLEIHGVNQDDVG 229



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 14/252 (5%)

Query: 1970 DDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            D   + E P F  P +N  + EG     E  +    +P  +V W+ NG+P+  G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLD 82

Query: 2030 YDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYL-DTLDEQRLKK 2087
                G  +L I   + ED G Y C+ATN  G    T  + V+      L   +  + L  
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                   E    I  E P   P F T L  +  +KEG    F C++     P +T  W  
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKITGRPQPQVT--WLK 196

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG---- 2203
                ++   R   +   G   L+I     +D G Y C   N  G+A  +  L + G    
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256

Query: 2204 HRNIILDTQHPN 2215
            +R+ + +T+  N
Sbjct: 257  NRSFVRETKATN 268



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 74/305 (24%), Positives = 117/305 (38%), Gaps = 21/305 (6%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P FE   ++    +    KF  ++ G P P V+W  +  P V   + S+   E  G   L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTP-VRRQEGSIEVYEDAGSHYL 472

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            + +    D G Y+CTA N  G+  CS  +Q E               +  +  +E + +
Sbjct: 473 CLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCA-VIEGQDF 531

Query: 192 GTQGYT--TEQSRQT-----QKVAYTNGTDHSSTDDFKV------DTFEYRLLREVSFRE 238
             Q     T   R T     Q + Y   T  +   +  +      D   Y  L E +  +
Sbjct: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591

Query: 239 SITKRYVGESDVQISTEIDRSLGPVSP-----PKIAQKPRNSKLQEGADAQFQVQLSGNP 293
                +V   + + S + +  L PV+P     P   Q   + K+ +G+     VQ+SGNP
Sbjct: 592 VSCSAWVTVHEKKSSRKSEYLL-PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
            P V W  NG  +  S            +L ++     D+G YT  A N  G + T   L
Sbjct: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710

Query: 354 AVESP 358
            V+ P
Sbjct: 711 TVQEP 715



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 69/232 (29%), Positives = 101/232 (43%), Gaps = 27/232 (11%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V+  AP F+  +KD  V E Q   F  +    G P  R+ WL NG PI+ + R T   + 
Sbjct: 509  VMEVAPSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EA 563

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G   L+++   PED GTYTC A N LG+   S+ + V  K S                  
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS------------------ 605

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             S + +    V  +   AP F+  L+   K+ +G       ++   P P   V W  NG 
Sbjct: 606  -SRKSEYLLPVAPSKPTAPIFLQGLS-DLKVMDGSQVTMTVQVSGNPPP--EVIWLHNGN 661

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             +Q    +         +L I  V+ ED+G YTC+A N+ G+  +   L VQ
Sbjct: 662  EIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 61/225 (27%), Positives = 102/225 (45%), Gaps = 13/225 (5%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P    P F+   R    + EG TA FE +V    +P  ++ ++ NG+ + S  RF +   
Sbjct: 28   PLTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCG 84

Query: 2297 F-GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRE 2355
              G  SL I     ED G+Y+ +A N  G     +++ +T +GS   +  +P   + + +
Sbjct: 85   IRGTFSLVIHAVHEEDRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2356 LESAEPFK-RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
              SA   + RP I        P F   L  +  ++EGQ   F C++   G P  +V W +
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKI--TGRPQPQVTWLK 196

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                ++ S+R++ +   G   + I  V  +D GVY C   N  G+
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 26/240 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++ P F    +   + E   A+FE    G P P + W+R   PI +   F +      + 
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG----------------- 4509
             L+I  V  ED   +   A N  G  + +  L VE    +  G                 
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149

Query: 4510 -------GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                   G  PP F      V V  GQ+ R   K+TG     V WLK    +QP  R  +
Sbjct: 150  ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE-CVVSLPATKDKPKPQTKAANA 4621
             E++G   L I      D G Y C+ +N +G+A   AE  +  L +       +TKA N+
Sbjct: 210  SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 10/224 (4%)

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
            + + D  C      T D  K ++++    P   + L+D  VAEG+ +   C++   P  T
Sbjct: 1070 DVKNDVNCKRGHAGTTDNEK-RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W    K +K +K+  +S+     ++ I +A PED G YKCVA N AG+   + ++ V 
Sbjct: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD 1188

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQ--ITSKIKPTIQWLREGALIPET---PDFQ 4768
                ++N  A   ++        P    T+   T K KP  +   + A+ P+    P+ Q
Sbjct: 1189 DAPASENTKA-PEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  G  +V L G      T   TC       Q++ S  + V++
Sbjct: 1248 KVRAG-ESVELFGKV--TGTQPITCTWMKFRKQIQESEHMKVEN 1288



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 67/227 (29%), Positives = 97/227 (42%), Gaps = 27/227 (11%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F + L     + EGQ    +C +   P P  R+ W  NG+ +Q     R++ + G A
Sbjct: 513  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 566

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
             L I     ED G YTC A N LGQ   S  + V  K+S            K +YL   +
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----------SRKSEYLLPVA 616

Query: 1963 RYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ 2022
              K            P F + + + +V +G  V +  T+    +P   V W  NG  +Q+
Sbjct: 617  PSKPTA---------PIFLQGLSDLKVMDGSQVTM--TVQVSGNPPPEVIWLHNGNEIQE 665

Query: 2023 GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
               F         +L I   + EDTGTY C+A N+ GE  T + + V
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 109/491 (22%), Positives = 182/491 (37%), Gaps = 27/491 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+ P  N   + EG     E R+   G P  +V W  NG+ +T G RF          
Sbjct: 33   PAFILPPRNLC-IKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 1237 LDIIHAT-SADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
              +IHA    D G+YT  A N  G+   + +   +E S      Q  Q +    L +  +
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVT-VELTVEGSFA---KQLGQPVVSKTLGDRFS 145

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                + R  I     P+F+  L  +   EG      C++   G    +V W     P++ 
Sbjct: 146  ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQP 203

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              R   + +     L++  V  +D GVYTC   N  G+A  S  L +       L+S + 
Sbjct: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG-----LDSANR 258

Query: 1416 SGLEKIQYLEDTSRYKKTDIID-ESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            S + + +      R + T++I  ES         + K+  +   G    +    +P    
Sbjct: 259  SFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
              K+E  K+  P T      P+      ++ +     +         V     +E     
Sbjct: 319  ESKLESCKD-SPRTAPQ--TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA 375

Query: 1535 TCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
              R  T   R    + GL    V+  ++   R  M  +  +  P   +  ++ E+KE Q 
Sbjct: 376  PPRPATFPTR----QPGLGSQDVV-SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET-NNFGFVALDIMSCLPEDSGTYTCR 1653
              F   +  +     +V W+    P++      E   + G   L ++     DSGTY+C 
Sbjct: 431  VKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488

Query: 1654 AINALGEAVTS 1664
            A NA G+   S
Sbjct: 489  ASNAQGQVSCS 499



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 1/98 (1%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLR 4681
            P   + ++D  V EG A  F CKI G P P V W+K D+ I+ S++FQ+    D   +L 
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
            IS+   +D+  Y C A NS G  T  A+L V   ++ +
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 71/270 (26%), Positives = 105/270 (38%), Gaps = 23/270 (8%)

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G V  VA +   +T+     + ++   +  AP F+     L ++EG       R  G P 
Sbjct: 2   GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 520 PRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P++TW ++G PI       +     G  +L I      D   Y C A N +G     AR 
Sbjct: 62  PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG-----ARQ 116

Query: 579 YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQ 638
                       K+L  P  +K                 VE  RP I  GE      PP+
Sbjct: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSASA-------VE-TRPSI-WGE-----CPPK 162

Query: 639 FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDM 698
           F   L  V   EG    F  +I   G P  ++ WLK    ++ S+R +   + G   L++
Sbjct: 163 FATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220

Query: 699 LSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +N  D G YTC  V+ +G A   A L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 69/245 (28%), Positives = 100/245 (40%), Gaps = 29/245 (11%)

Query: 1298 TKQVREDITVMQ-APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            T QV E + VM+ AP FS  L +   +EG +  L+C ++  G    R+ W  NG+PI+  
Sbjct: 501  TLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA 557

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
               R   E     L +    PED G YTC A N LG+   S  + V  KK          
Sbjct: 558  ---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK---------- 604

Query: 1417 GLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL 1476
               K +YL   +  K T          P F+     ++ V++G  V    ++    +   
Sbjct: 605  SSRKSEYLLPVAPSKPT---------APIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPP 652

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            +V W  NG  +     F         +L I ++  ED+G YTC A N  G       LT 
Sbjct: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712

Query: 1537 RSTTD 1541
            +   D
Sbjct: 713  QEPHD 717



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 1/93 (1%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYT 4570
            V P F+ T +++ V  G   R D K+ G    +V W K+ + ++     +I  +EDG  +
Sbjct: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            L+I +    D  KY C A+NS GEA C AE +V
Sbjct: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 64/250 (25%), Positives = 102/250 (40%), Gaps = 11/250 (4%)

Query: 3125 ATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKI 3183
            A++   +  +SV    VD     + P F    +N+  +K+G +A FE  V    +P  ++
Sbjct: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QV 64

Query: 3184 EWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             W+ NGQP+    R        G   L I      D G+Y C A N  G    + T+   
Sbjct: 65   TWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELT 122

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +G    +  QP     + +  S    + + PS     PPKF T++  V  + EGQ   F
Sbjct: 123  VEGSFAKQLGQPVVSKTLGDRFSASAVETR-PSIWGECPPKFATKLGRVV-VKEGQMGRF 180

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
              ++     P  +V W      L    R       G+ +L+I    +++ G Y C+  N 
Sbjct: 181  SCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238

Query: 3363 LGRDSTKANL 3372
             G+ S  A L
Sbjct: 239  SGKASMSAEL 248



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
            +K++  ED S+       E   +  P F   +    ++ EG +A ++C+IE YPDP   V
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPE--V 1840

Query: 1879 EWYFNGKVLQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             W+ + + ++    ++   D  G  +L I  V G+D  +YTCKA+N+LG+A  +  L V+
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900

Query: 1938 SKE 1940
            + E
Sbjct: 1901 TME 1903



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/243 (23%), Positives = 99/243 (40%), Gaps = 35/243 (14%)

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-- 425
           S +I+ T       R++      AP F+   ++  + EG   +F+ RV G P P+VTW  
Sbjct: 9   SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68

Query: 426 ----------FINDRQIRDDYN---HKILVNESGNHALMITN--------VTLSDSG--- 461
                     F+ D  IR  ++   H +   + G +    TN        V L+  G   
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128

Query: 462 ------VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
                 VV+    ++   +A + R ++  +     PKF  +   + V+EG+    + +  
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGE---CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           G P P++TW K  VP+ P+  + +    G   L+I      D   Y C   N +G  +  
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245

Query: 576 ARL 578
           A L
Sbjct: 246 AEL 248



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/217 (26%), Positives = 91/217 (41%), Gaps = 14/217 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGL 2580
            EG  A +E RV   G P  +  W+ NG  +  G RF       G  +L I++V   D G 
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2581 YMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQI--QLKEAAMNKVPEMFVDTGV 2638
            Y C+A N +G                  Q  +P   + +  +   +A+   P ++ +   
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFA--KQLGQPVVSKTLGDRFSASAVETRPSIWGEC-- 159

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
               P F T L     + EGQ      ++  R  P  ++ W K  V L   AR+  +   G
Sbjct: 160  --PPKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNG 214

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            +  L I+ +  DD G+YTC   N  G+A  +A + I+
Sbjct: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 6/119 (5%)

Query: 1415 PSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            P   EK++  ED S+     + +E   +KP F    + +E V+EG    F+CK+E   D 
Sbjct: 1780 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1838

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
              +V WFK+ Q +     F+  +D  G  +L I D+  +D   YTC+AVN +G  E +C
Sbjct: 1839 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATC 1893



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 6/103 (5%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            + EE+P  +P F   +  LE + EG  A F+C++E   DP +   WF + Q IR    ++
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQ 1856

Query: 2160 TTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              +D  G  +L I     +D   Y CKA N LGEA  TCT ++
Sbjct: 1857 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCTAEL 1897



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 53/219 (24%), Positives = 93/219 (42%), Gaps = 30/219 (13%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLR 4681
            P  I P ++  + EG   +F  ++ G P P V W++ G  +    ++         ++L 
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4682 ISEAFPEDEGDYKCVAYNSAG--RVTVAAKLK------VTQPDQADNL------------ 4721
            I     ED G Y C A N +G  +VTV   ++      + QP  +  L            
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4722 PAL---------TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
            P++         T L  +VV EGQ  +F  +IT + +P + WL+    +  +    +  +
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                VL I    ++D G +TC     +G+   SA+L ++
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 67/267 (25%), Positives = 104/267 (38%), Gaps = 22/267 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F++V KD   I EGQ    + S+   G     I W  NG+ I+ +   R+    G+  
Sbjct: 514  PSFSSVLKDCAVI-EGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK-----------PRFTTHIQ 3156
            L I      D GTY+C A N  GQ   S  +   +K   +K           P     +Q
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             +  LK    +    TV    +P  ++ W HNG  ++ S             L I     
Sbjct: 628  GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFP 687

Query: 3217 HDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPST 3276
             D+G Y C A+N  GE  T+A +          +  QP  ++K R + +  G        
Sbjct: 688  EDTGTYTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWFISKPRSVTASLGQSVLISCA 743

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFE 3303
             + +P   +  ++D   L +  + HFE
Sbjct: 744  IAGDPFPTVHWLRDGKALCK-DTGHFE 769



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 59/227 (25%), Positives = 96/227 (42%), Gaps = 27/227 (11%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++ AP F++ LK    ++EGQ   L+  V  R  P  +I W  NG  +      +ST + 
Sbjct: 510  MEVAPSFSSVLKDC-AVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 563

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI-EDRHWLLGESLHPDSLDRIGAL 2756
            G+  L I     +D G YTC A N LG+   +A + + E +     E L P +  +  A 
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA- 622

Query: 2757 XXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL 2816
                              +F+  L+++   +G  +     V+ S +P  ++ W  N   +
Sbjct: 623  -----------------PIFLQGLSDLKVMDGSQV--TMTVQVSGNPPPEVIWLHNGNEI 663

Query: 2817 PSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +      +  SL I   + ED+G YTC+A NS G   T   L
Sbjct: 664  QESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 5/143 (3%)

Query: 2319 AINALGHCTS-AISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
            A+ A+G  +S A+   ++ + S       P   EK+   E         + E     +P 
Sbjct: 1751 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1810

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSM 2436
            F++ +++++ + EG  A FDC++    DP  +V WF++++ I +S      +D  G  S+
Sbjct: 1811 FSKTIRDLE-VVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867

Query: 2437 TISHVRDEDEGVYMCRASNLLGE 2459
             IS V  +D+  Y C+A N LGE
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGE 1890



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 62/232 (26%), Positives = 94/232 (40%), Gaps = 28/232 (12%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   LK    ++EGQ   F  +   +      + W  NG+ I  A   ++  + G   
Sbjct: 514  PSFSSVLKDC-AVIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I     ED G YT +A NA G+   SA +TV  + S                  +S++
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----------------RKSEY 611

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            + P   +     + P+F+Q LS+   V +G  + +  ++   G+P   V W HNG  +  
Sbjct: 612  LLP---VAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQE 665

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
               F         +L I      DTG YT  A N  G   T A++ V E  D
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 54/227 (23%), Positives = 89/227 (39%), Gaps = 11/227 (4%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            + EG+ L L+ QV   +DP   I W  NGK L+      L+ +    ++ +      D G
Sbjct: 1109 VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166

Query: 2983 IYTCKAYNKRGEAFTSSTVYC----TSKDNLIERTQHPKGTEGLEKIQNLED--SLRKEP 3036
            +Y C A N  G+A  S  V       S++      +  +    L  +   E   +++K+P
Sbjct: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
              +       PP+    F +   +  G+       +  TG Q +   W    K I+ S  
Sbjct: 1227 APKTPPKAAMPPQIIQ-FPEDQKVRAGESVELFGKV--TGTQPITCTWMKFRKQIQESEH 1283

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            ++   +     L IL  +    G Y+    NK G  +  V L  VDK
Sbjct: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 44/140 (31%), Positives = 66/140 (47%), Gaps = 5/140 (3%)

Query: 4374 GDKEITRKITSTETTE-IEHKAQTQERVVEGPV--KPSKPPIFTKKMQPCRVFEHEQARF 4430
            G K  T   TS    E +E +    +  +E     KP   P F+K ++   V E   ARF
Sbjct: 1769 GRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARF 1828

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489
            + + +G P P + W++++  I+ S  FQI +       LII  V  +D A +   A N  
Sbjct: 1829 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1888

Query: 4490 GTAKCSANLVVEEKRRQGRG 4509
            G A C+A L+V E   +G G
Sbjct: 1889 GEATCTAELIV-ETMEEGEG 1907



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/155 (30%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 710  TCRAVSATGVAETKAVLH-VTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ 768
            T  AV A G   + A++  ++ R +   +   P   + ++  ED S+   +   EE+   
Sbjct: 1748 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1807

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827
            +P F + ++DL E+ EG  A F+ ++    DP   V W+KD + I  S      ++  G 
Sbjct: 1808 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             SL I  +  +D   YT +AVN LGEA  TA + V
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 67/228 (29%), Positives = 98/228 (42%), Gaps = 28/228 (12%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F + +KD  ++ EG    F  +    G    R+ WL +G+P++ + R T     G   
Sbjct: 514  PSFSSVLKD-CAVIEG--QDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAE 567

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I+     D G YTC A NA+GQ + SA +T+  KK             K +YL   + 
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKSEYLLPVAP 617

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
             SK T         P FL  L    K+++G       +V    +    V W  NG +I  
Sbjct: 618  -SKPT--------APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 665

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            +            +L I  V  ED+G YT  A N+AGE +  A +TV+
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 46/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 983  TCRAYNAIGQATTSANLTIVT-KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            T  A  AIG+ ++ A ++ ++ +K        P   EK++  ED S+       E K   
Sbjct: 1748 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1807

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGY 1100
            KP F   ++   ++VEG +A F+ ++E   D    V W+ + + I  +   Q  Y + G 
Sbjct: 1808 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPD--PEVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             +L I+ V  +D   YT  A N+ GEA  +A + VET
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1901



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F +  ++    +G  A+F+ K+ G P P V W +    + E   + + Y+E  G+ SL
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1867

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            +I  +   D+ +YTC A N  GEA C+
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCT 1894



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 20/239 (8%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P FI   ++  ++E    +FE RV    +P  ++ W+RNG+ + SG R+     + G  S
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  V+ ED G+Y C A N  G    + T+      ++ ++    + + +      +  
Sbjct: 91   LVIHAVHEEDRGKYTCEATN--GSGARQVTV------ELTVEGSFAKQLGQPVVSKTLG- 141

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
               ++++    T   ++    + PP+F T++  +  + E +  +F C++   G P  +V 
Sbjct: 142  --DRFSASAVETRPSIWG---ECPPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVT 193

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W     PL    R +     G   +    V  +D G Y C   N  G     A +   G
Sbjct: 194  WLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 12/238 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F   ++D+ VAE +    + ++    DP   + W  NG  ++ +  +    +    +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-------QSKASLQLESQHESALQKIQ 1822
            ++++   PED G Y C A N+ G+A  S  + V        +KA      + +S+L  + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1823 QLEDSSRYQRREDVEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
              E  +  +++   +     A P  I Q     K+  G+S     ++     P +   W 
Sbjct: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG-TQP-ITCTWM 1272

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
               K +Q     +  N    + L IL    E  G YT    N LG   + + L V  K
Sbjct: 1273 KFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 3/130 (2%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +L   ED S+    +  +E     P F+  ++D+ V E  AA F+ ++    DP+  V W
Sbjct: 1785 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1842

Query: 1747 LRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             ++   I  S      +D  G  +L +  V  +D   YTC+A+N LGEA  ++ L V++ 
Sbjct: 1843 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902

Query: 1806 ASLQLESQHE 1815
               + E + E
Sbjct: 1903 EEGEGEGEEE 1912



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 70/311 (22%), Positives = 117/311 (37%), Gaps = 34/311 (10%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            ++EGQ   L+  V  +  P  +I W  NG+ ++     + T + G   L + D    D G
Sbjct: 525  VIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHG 579

Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDD 3042
             YTC A N  G+   S+ V           T H K +    K + L      +P      
Sbjct: 580  TYTCLAENALGQVSCSAWV-----------TVHEKKSS--RKSEYLLPVAPSKP------ 620

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
                 P F     D+  +   Q+     ++  +G+    + W +NG  I+ S        
Sbjct: 621  ---TAPIFLQGLSDLKVMDGSQVT---MTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
                 L I      D+GTY+C A N  G+      L   +   G +P F +  +++    
Sbjct: 675  GTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA-S 733

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST-RIKTVSDFGFVVLDIAYTQNHDSGE 3221
             GQS    C +    DP   + W  +G+ +   T   + + +     L +   Q   +G+
Sbjct: 734  LGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791

Query: 3222 YVCRAYNKYGE 3232
            Y     N+ GE
Sbjct: 792  YEILLKNRVGE 802



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 38/120 (31%), Positives = 62/120 (51%), Gaps = 5/120 (4%)

Query: 1953 EKIQYLEDDSR-YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
            EK++  ED S+ +  AV ++   V KP F K I++ EV EG     +  +    DP   V
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHV-KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EV 1840

Query: 2012 EWYCNGRPVQQGHRFKTTYDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             W+ + + +++   F+  YD  G  +L I     +D   Y CKA N++GEA  T+ + V+
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 55/235 (23%), Positives = 92/235 (39%), Gaps = 14/235 (5%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F + L ++   EG  + L+C++    D    + W  NGK +KT      + E    +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV------IAKKDLILESQHP-SGLEKIQ 1422
            + +    PED G+Y C A N  G+A  SC + V         K   ++S+ P S L  + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1423 YLEDTSRYKKTDI--IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEW 1480
              E  +  KK           + P+ +  P+  + V  G+ V    K+       +   W
Sbjct: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKV--TGTQPITCTW 1271

Query: 1481 FKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             K  + +      +  +      L I+    E  G YT    N +G+ +    LT
Sbjct: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1326



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 8/123 (6%)

Query: 43  HFTRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPV 102
           H ++   +   S  D  P+T   P    PP      +N    +G  AKFEG++RG P P 
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEA-PAFILPP------RNLCIKEGATAKFEGRVRGYPEPQ 63

Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           V+W R   P+    ++ +    + G  SL+I  +   D G+YTC A N  G    +V + 
Sbjct: 64  VTWHRNGQPITSGGRFLLDCGIR-GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122

Query: 163 PEG 165
            EG
Sbjct: 123 VEG 125



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 61/212 (28%), Positives = 85/212 (40%), Gaps = 26/212 (12%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG     +C V     P +T  W  NGQ I+     R+T + G   L I     ED GTY
Sbjct: 527  EGQDFVLQCSVRGTPVPRIT--WLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 581

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPP 2242
             C A N LG+   +C+  V  H             +  R+ E       + V   K + P
Sbjct: 582  TCLAENALGQV--SCSAWVTVHEK-----------KSSRKSEYL-----LPVAPSKPTAP 623

Query: 2243 RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
             F+  L     V +G       QV    +P   + + HNG  +Q +  FH        SL
Sbjct: 624  IFLQGL-SDLKVMDGSQVTMTVQVSG--NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             IQ   PED G Y+ +A N+ G   +   +TV
Sbjct: 681  WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 58/243 (23%), Positives = 97/243 (39%), Gaps = 17/243 (6%)

Query: 258  RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            RS    + P   QK ++  + EG     Q Q+S +P   + W  NG+ L  + K  I++ 
Sbjct: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1148

Query: 318  HNHT-TLRVRNTQKSDSGHYTLLAENPNG-----CIVTSGYLAVESPTESYVQDQRSQYI 371
                 ++ +      D G Y  +A+N  G     C VT         T++     R    
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208

Query: 372  TDTQQRETEERIEISEK---------ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            +      TE    + +K         A+ PQ ++  +D+ V  G+      +VTG     
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             TW    +QI++  + K+  +E+G+  L I        G  T +  NK G    Q  L V
Sbjct: 1269 CTWMKFRKQIQESEHMKVENSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327

Query: 483  IEK 485
            ++K
Sbjct: 1328 VDK 1330



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 63/218 (28%), Positives = 91/218 (41%), Gaps = 28/218 (12%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F + L+    V EG+    +C V     P  RI +  NG+ +Q A     T + G   
Sbjct: 514  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYARS---TCEAGVAE 567

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L IQ  +PED G Y+  A NALG  + +  +TV  K S    S++ E             
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSE------------- 610

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            +  P  P   T   P+F Q L ++  + +G       ++   G+P  +V W  N   I++
Sbjct: 611  YLLPVAPSKPT--APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 665

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S            S+ I  V  ED G Y C A N  GE
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGE 703



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 35/237 (14%)

Query: 3558 PEFTTTPSDLILSENSSAHFEC--RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            P F++   D  + E      +C  R  PV     R+ W  NG+P+      ++  + G  
Sbjct: 514  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVP----RITWLLNGQPI---QYARSTCEAGVA 566

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I      D G YTC A N  G+  VSC   V              H K  +   + L
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQ--VSCSAWVT------------VHEKKSSRKSEYL 612

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
                     + +   KP  P F   + D + V +G  V    +V   G+P   + W HNG
Sbjct: 613  ---------LPVAPSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 660

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
                     H        +L I  ++  D G YTC A N  G   T A +T     D
Sbjct: 661  NEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 4/154 (2%)

Query: 1251 TVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            T  AV  +G   + A++  +  R        +    E+++  ED ++   +   +     
Sbjct: 1748 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1807

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD-YV 1368
             P FS+ + ++E VEG+    +C+++   D    V WF + + I+    F+  Y+ D   
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNC 1865

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L +  V  +D   YTC+A N LGEA  +  L V
Sbjct: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 60/244 (24%), Positives = 100/244 (40%), Gaps = 16/244 (6%)

Query: 2226 QGHSTRIEVE---EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
            +GH+   + E   E + + P F  +L+   HV EGK    +CQV    DP   I +  NG
Sbjct: 1079 RGHAGTTDNEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSS--DPPATIIWTLNG 1135

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV----TAKG 2338
            K L++     ++ +    S+ I+  +PED G Y   A N  G    +  +TV     ++ 
Sbjct: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195

Query: 2339 SIISE--SQRPE-GLEKIRELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTA 2394
            +   E  S+RP+  L  +   ES    K+   P+ P     P           ++ G++ 
Sbjct: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255

Query: 2395 HFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
                ++   G   +   W +  K I++S  +   +      +TI   R E  G Y     
Sbjct: 1256 ELFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1313

Query: 2455 NLLG 2458
            N LG
Sbjct: 1314 NKLG 1317



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 3/134 (2%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + +  + +G+     + E   S+    PPK A K     ++EG   +F  +++G P+P+V
Sbjct: 133 QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-- 355
           TW K    L  S +  +   +    L +    + D G YT L  N +G    S  L++  
Sbjct: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252

Query: 356 -ESPTESYVQDQRS 368
            +S   S+V++ ++
Sbjct: 253 LDSANRSFVRETKA 266



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 61/232 (26%), Positives = 91/232 (39%), Gaps = 28/232 (12%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F+  +KD   V EG      C V   G P  RI W  NG+P        +  + G   
Sbjct: 514  PSFSSVLKD-CAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPI---QYARSTCEAGVAE 567

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L I      D G YTC A N  G  + +A +T   K+            S  K + L   
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK------------SSRKSEYL--- 612

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
             +  AP +     T P F+  +    ++  +G +    V+   +P   + W  NG  +  
Sbjct: 613  -LPVAPSK----PTAPIFLQGLSD--LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
               +         SL I  V+ ED+G Y C A N  GE  T+A ++ ++  D
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 4/100 (4%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GY 966
            KP F   I+D + + EG  A F+ ++E   D    V W KD + +  S      ++  G 
Sbjct: 1808 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
             +L I  V   D   YTC+A N++G+AT +A L + T ++
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 55/224 (24%), Positives = 87/224 (38%), Gaps = 12/224 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG  +  +C V  S DP   I W  N K L +      + + S  S+ I
Sbjct: 1100 FKQKLQDVHVAEGKKLLLQCQV--SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQ-----GKAGLEAVEQA 2890
                 ED G+Y C A N  G A  S  +    D     +T+ P+      K+ L  V   
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQV-TVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216

Query: 2891 E-EARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949
            E +A + K   P  P      P+ II    + ++  G+ + L G+V       +   W  
Sbjct: 1217 ESDATVKKKPAPKTPPKAAMPPQ-IIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMK 1273

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
              K +++    K+ +      L ++   +   G YT    NK G
Sbjct: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 4/124 (3%)

Query: 2613 PESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            P + E+++ +E       E   +      P F+  ++  + +VEG     + ++E   DP
Sbjct: 1780 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1838

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
              ++ WFK+  ++      +  +D  G  +L I+ +  DD   YTCKA N LGEA  TA 
Sbjct: 1839 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1896

Query: 2732 IKIE 2735
            + +E
Sbjct: 1897 LIVE 1900



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 5/101 (4%)

Query: 3687 IEDEKPN-PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
            + +EKP+  P F+  I+D ++V EG    FDC++E   DP   + WF + +         
Sbjct: 1800 VAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQ 1856

Query: 3746 -TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               ++ G  +L I  +   D  +YTC+A N  G AT TA++
Sbjct: 1857 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 4/120 (3%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            EKL++ ED      +   EE+    P F+  + ++E + EG  A F+ ++    DP  +V
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV-EGSAARFDCKIEGYPDP--EV 1840

Query: 3455 EWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             W+ + +S++    F+  + + G   L IS    +D  +Y C+A N+ GEA  TA + V+
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 55/226 (24%), Positives = 90/226 (39%), Gaps = 14/226 (6%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F  +L     ++EG+    +C++    DP   + W  NGK L++      S +    
Sbjct: 1097 APAFKQKLQD-VHVAEGKKLLLQCQVSS--DPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-------QSKESIIRDSQHESALEKI 1955
            ++ I     ED G Y C A N+ GQA  S ++ V        +K   ++  + +S+L  +
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213

Query: 1956 QYLEDDSRYKR--AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW 2013
               E D+  K+  A +        PQ  +  ++ +V  G  V L   +T     T    W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT--CTW 1271

Query: 2014 YCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
                + +Q+    K         L IL A  E  G Y     N +G
Sbjct: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 1/87 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYE 4785
            +RD+ V EG  A+F  +I     P + W ++   I E+  FQ+ + E  N  L+I +   
Sbjct: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +D   +TC+A  + G+   +A+L+V++
Sbjct: 1875 DDDAKYTCKAVNSLGEATCTAELIVET 1901



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 52/251 (20%), Positives = 93/251 (37%), Gaps = 10/251 (3%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E   E     P F + LQD+  + EG+    + Q++  SDP   + W  +G+ +  +  I
Sbjct: 1088 EKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFI 1144

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV----AARSTVTADLGIP 875
                     S++I     ED G Y   A N  G+A  +  + V    A+ +T   ++   
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935
              +  +                     P++   P+     +DQ  ++ G       ++  
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ-KVRAGESVELFGKVT- 1262

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             G   +   W+K  + ++ S  +    +     LTI +      G YT    N +G    
Sbjct: 1263 -GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQA 1321

Query: 996  SANLTIVTKKD 1006
              NLT+V K D
Sbjct: 1322 QVNLTVVDKPD 1332



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 5/108 (4%)

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            E  +++ +  +    +E+P V   P F   I+   V E    RF+C++E   DP+  + W
Sbjct: 1787 ESEEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1842

Query: 3866 YRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            +++ + +     ++  YD  G  SL I  V  +D  +Y C+AVN  GE
Sbjct: 1843 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 32/232 (13%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F + ++D   ++EGQ    +  +     P  ++ W  NG+ + +    R+  + G+  
Sbjct: 514  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401
            L I     E+ G Y C+A N LG+ S  A +    K++      L               
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL--------------- 612

Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461
                      V   K  AP+F   LS+++ + +G       +++    P  +V W  NG 
Sbjct: 613  --------LPVAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVSGNPPP--EVIWLHNGN 661

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             ++    F          L I   +PED+G Y C A+N+ GE  T A + VQ
Sbjct: 662  EIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 58/258 (22%), Positives = 90/258 (34%), Gaps = 10/258 (3%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G++GT D        G  P F     D+ ++E      +C++   +D    + W  NGK 
Sbjct: 1080 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKT 1137

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI--IL 3657
            L T   +    +     + I      D GLY C A N  G+A  SC++ V          
Sbjct: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1197

Query: 3658 EPQLPSHF-KSGTESIQKLEE--TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVH 3714
             P++ S   KS    +   E   T+ K+       +   PP+  ++  ++  V  G  V 
Sbjct: 1198 APEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI-IQFPEDQKVRAGESVE 1256

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
               +V   G   +   W    +       +   N      L I        G YT    N
Sbjct: 1257 LFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVEN 1314

Query: 3775 KWGSATTTAKITCSAKRD 3792
            K GS      +T   K D
Sbjct: 1315 KLGSRQAQVNLTVVDKPD 1332



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + E+R E   +  AP F +  QD  V EGK     C+V+  P   + W +N + ++    
Sbjct: 1086 DNEKRSE--SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-K 1142

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE---KEQVVAPKFV 494
              IL  E    ++ I      D G+  CVA+N +G+    C++ V +    E   AP+  
Sbjct: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202

Query: 495  ER 496
             R
Sbjct: 1203 SR 1204



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 57/243 (23%), Positives = 98/243 (40%), Gaps = 19/243 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L+  + + EG+    + +V   SD   T+ W  NGK + +   I    +    +
Sbjct: 1098 PAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            + I     ED G+Y  VA+N AG+A+ S  +TV+   + + +   +    K+R  + S  
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT---KAPEMKSRRPKSS-- 1209

Query: 1163 VEPMYQIEEIS--KSKPVFVQP--LSNPPPV---SEGKNIHLECRLEPMGDPT----MRV 1211
            + P+   E  +  K KP    P   + PP +    E + +     +E  G  T    +  
Sbjct: 1210 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1269

Query: 1212 EWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             W    + +      K         L I+ A     G YT+   N LGS      + V++
Sbjct: 1270 TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329

Query: 1272 RSD 1274
            + D
Sbjct: 1330 KPD 1332



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 7/137 (5%)

Query: 2201 VAGHRNIILDTQHPNGLEKIRQLE--AQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            ++G ++       P   EK+   E  +Q     +  E+P + P  + ++      V EG 
Sbjct: 1767 LSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP--YFSKTIRDLEVVEGS 1824

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSV 2317
             A F+C++E   DP   + ++ + ++++ +  F I +D  G  SL I     +D  +Y+ 
Sbjct: 1825 AARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882

Query: 2318 KAINALGHCTSAISMTV 2334
            KA+N+LG  T    + V
Sbjct: 1883 KAVNSLGEATCTAELIV 1899



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 3/131 (2%)

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
            E+++  ED S+     + +E     P  + +++++E+ EG  A F+ ++    D   +V 
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVV 1841

Query: 1613 WYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
            W+ +++ ++    F  + +  G  +L I     +D   YTC+A+N+LGEA  +   IV +
Sbjct: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1901

Query: 1672 KKSIYLESQHE 1682
             +    E + E
Sbjct: 1902 MEEGEGEGEEE 1912



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           P +P+ PIF Q   + +   G       ++ GNP P V W      + E   +   + ++
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQR 674

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
               SL I+++ P D G YTC A N  GE
Sbjct: 675 GTQHSLWIQEVFPEDTGTYTCEAWNSAGE 703



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 52/242 (21%), Positives = 89/242 (36%), Gaps = 12/242 (4%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            E +G AP F   L ++ ++ EG+    + +++   DP   + W  NGK+LK  ++F    
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT-TKFIILS 1147

Query: 3474 DFGFVI-LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ---GKRNIILESQLPKGME 3529
              G +  + I    PED G Y C A N+ G+A  +  + V       N        +  +
Sbjct: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207

Query: 3530 GTIDKIAALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
             ++  +   E  +       P+   ++  PP+    P D  +    S     ++      
Sbjct: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQ 1265

Query: 3588 SMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
             +   W    K +     +K  N      L I    Q   G YT    N+ G       L
Sbjct: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325

Query: 3648 QV 3649
             V
Sbjct: 1326 TV 1327



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 56/231 (24%), Positives = 89/231 (38%), Gaps = 28/231 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P F+ VL   + + EGQ    +  V   G P  R  W +NG  ++     R+T + G   
Sbjct: 514  PSFSSVLKDCAVI-EGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L I   +  D G Y C A N  G                        +W  +  K+++  
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCS-------------------AWVTVHEKKSSRK 608

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                + V      APIF   L    K+++G  V +  QV     P  ++ W  NG  +  
Sbjct: 609  SEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQVTMTVQVSGNPPP--EVIWLHNGNEIQE 665

Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
                         +L I  +  +D+G YTC+A N  GE  + A + +++ H
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIK 4749
            GD K VA +   + +++              PA + P R++ + EG  A+F+ ++    +
Sbjct: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            P + W R G  I     F ++  G      L+I   +EED G +TC AT  +G  + + +
Sbjct: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 4808 LVVK 4811
            L V+
Sbjct: 121  LTVE 124



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 3/116 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMHDFGYVA 1769
            P F    +   V ENQ   F   +   G PK  V W   G P+      +    D G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            L +      DSGTY+C A N  G+   S TL V+  A +++     S L+    +E
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F+  L  +  M+G ++    ++   G+P  ++ WL NG  I+ S  F    R    SL
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +  +  +D+G YTC A ++ G   T+AVL V
Sbjct: 681 WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 630  EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            E++ +  P F   ++ +  +EG    F+ +IE   DP  ++ W K+ QSI  S  F   +
Sbjct: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDY 1859

Query: 690  -RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
               G  SL +  +   D  +YTC+AV++ G A   A L V
Sbjct: 1860 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 57/237 (24%), Positives = 91/237 (38%), Gaps = 33/237 (13%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F   L+D   + EG++  F  Q +    P  R+ W  +G+PI  +    S    G   
Sbjct: 514  PSFSSVLKDCAVI-EGQD--FVLQCSVRGTPVPRITWLLNGQPIQYAR---STCEAGVAE 567

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L+I     ED G+YT  A N LG+   +A + V  + +         +  Y+        
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-------SRKSEYLLPVA---- 616

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                         P     P F   + D + + +G       ++   G+    V WL +G
Sbjct: 617  -------------PSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 660

Query: 950  RPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
              ++ S            +L I+ V   D G YTC A+N+ G+  T A LT+    D
Sbjct: 661  NEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 27/226 (11%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F   LK    +EG     +  +   G P  +I WL NGQ I+ +    S    G   L
Sbjct: 514 PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 568

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
            +     +D G YTC A +A G     A + V  + +  +                 S+Y
Sbjct: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK-----------------SEY 611

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
               +  + T+  P F++ L DL ++ +G       Q++   +P   V W  +G  I  S
Sbjct: 612 LLPVAPSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 666

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                       SL I  +  ED G+YT  A N  GE  + A + V
Sbjct: 667 EDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/229 (25%), Positives = 81/229 (35%), Gaps = 27/229 (11%)

Query: 3988 METTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYL 4047
            +E   F  Q +  G P  ++ W  NG+P+ +  R T   + G   ++     PED G Y 
Sbjct: 526  IEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RST--CEAGVAELHIQDALPEDHGTYT 582

Query: 4048 CRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKA 4107
            C A N  G     A +                H K  +  R+ E    V P      SK 
Sbjct: 583  CLAENALGQVSCSAWVTV--------------HEK--KSSRKSEYLLPVAP------SKP 620

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH- 4166
              P     L D + V +G       +V+G+P P V+WL NGN I     +     G  H 
Sbjct: 621  TAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679

Query: 4167 FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
              I +    DTG                  L V   HD  +    + PR
Sbjct: 680  LWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 19/282 (6%)

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQ 1979
            + +  +G A     L   SKE + +D +++   ++      D+  +   Q  +     P 
Sbjct: 1045 ETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTA-----PA 1099

Query: 1980 FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDI 2039
            F + +++  V EG  + L+  ++  +DP   + W  NG+ ++       + +    ++ I
Sbjct: 1100 FKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 2040 LYAYAEDTGTYMCKATNAVGEAVTTSSVKVD---AKSGLYLDTLDEQRLKKI------QE 2090
              A  ED G Y C A N  G+A  +  V VD   A        +  +R K         E
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217

Query: 2091 LEKYERPKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
             +   + KP  +  P    P  +      + ++ G+      +V       +T  W    
Sbjct: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMKFR 1275

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            ++I+     +  +      L IL    E  G Y     NKLG
Sbjct: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F   L+    + EG+ + L+ QV   +DP   I W  NG TL T   +  + +  L 
Sbjct: 1097 APAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            ++SI     +D G+Y C A N  G+A  +  + ++D
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 11/154 (7%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT-TDSGTYSCRATNKWGQAEISVK-LEC 3140
            +W   G  + A  R+ ++     ++  + G K+ T S T    A     + ++S   LE 
Sbjct: 1744 KWQKTGNAVRAIGRLSSM----AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1799

Query: 3141 VDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199
            V + K   KP F+  I+++E + +G +A F+C +    DP+  + W+ + Q +R S   +
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQ 1856

Query: 3200 -TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                + G   L I+     D  +Y C+A N  GE
Sbjct: 1857 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP F+  L +   + EG++   +  +  T  P  ++ W  NG+ ++     R+ C+ G  
Sbjct: 513  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 566

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQL----PKGMEGTI-- 3532
             L I    PED G Y C A N  G+   +A + V  K++      L    P      I  
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECR 3580
              ++ L+   G+  T+T +     PPE     +   + E+   HFE R
Sbjct: 627  QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 16/245 (6%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            +S+G  P F   +Q++  + +G+    +C V    DP   I W  NG+ ++ +  I    
Sbjct: 1092 ESQGTAPAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1148

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATIN----CYGKGGVYLESLQP-D 3255
            +     + I      D G Y C A N  G  E   + T++            ++S +P  
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208

Query: 3256 SLAKIRELESLQGAQQQ-TPSTP--SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDP 3312
            SL  +   ES    +++  P TP  +A PP+ I Q  +  K+  G+S     ++      
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQII-QFPEDQKVRAGESVELFGKVTGTQ-- 1265

Query: 3313 DLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +   W    K++      +  +      L IL   +E+ G Y  +  NKLG    + NL
Sbjct: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325

Query: 3373 KCTSK 3377
                K
Sbjct: 1326 TVVDK 1330



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 42/151 (27%), Positives = 69/151 (45%), Gaps = 9/151 (5%)

Query: 1127 AQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNP 1186
            A +S     ++ +   TS ++    E    + ++ F+E +   EE    KP F + + + 
Sbjct: 1762 AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQA-FLEAV--AEEKPHVKPYFSKTIRDL 1818

Query: 1187 PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFVALDIIHATSA 1245
              V EG     +C++E   DP   V WF + +S+     F+  YD  G  +L I      
Sbjct: 1819 EVV-EGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1875

Query: 1246 DTGEYTVRAVNHLGSAHTSA--IVRVIERSD 1274
            D  +YT +AVN LG A  +A  IV  +E  +
Sbjct: 1876 DDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 4078 PKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGH 4137
            P    + EK+   E   Q   E V EE K    P F      + V EG  ARF C++ G+
Sbjct: 1777 PTSPLNAEKLESEEDVSQAFLEAVAEE-KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1835

Query: 4138 PKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P P V+W  +  +I     +++ YD
Sbjct: 1836 PDPEVVWFKDDQSIRESRHFQIDYD 1860



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT--YDGMYHFD 4168
            P F+  P  + ++EG  A+F  RV G+P+P+V W  NG  I +G R+ L     G +   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4169 IPKTRQYDTGK 4179
            I    + D GK
Sbjct: 93   IHAVHEEDRGK 103



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 3/110 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS-RVKTINDFGFVI 3616
            P+F + P    + EN +  F C +  +      V WF  G P+      ++   D G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGI--PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            L +     RD+G Y+C A+N  G+ + S  LQV+    + + P   S  K
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLK 521



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 40/129 (31%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 44  FTRQMTTQVESS--GDRQPITA--GRP---GEPSPPIFEQIFKNARFAQGGNAKFEGKLR 96
           F +Q+   V S   GDR   +A   RP   GE  PP F          +G   +F  K+ 
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE-CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P V+W +   PL    + S+  +E+ G   L I  +   D G YTC   N  G+A 
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSV--SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243

Query: 157 CSVYIQPEG 165
            S  +  +G
Sbjct: 244 MSAELSIQG 252



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 37/239 (15%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            ++   P F + +K   V E +    +C V  +  P  RI W  NG+ +      R+  + 
Sbjct: 509  VMEVAPSFSSVLKDCAVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 563

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            G   L I     ED G Y C A N  G+      +SC     +       +  ++SE L 
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQ------VSCSAWVTV----HEKKSSRKSEYL- 612

Query: 3945 QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPN 4004
             +     K T+ ++L                    Q  + L  M+ ++    +   G+P 
Sbjct: 613  -LPVAPSKPTAPIFL--------------------QGLSDLKVMDGSQVTMTVQVSGNPP 651

Query: 4005 MKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
             +V W  NG  +     F         ++    V+PED+G Y C A N  G   T+AV+
Sbjct: 652  PEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 54/241 (22%), Positives = 84/241 (34%), Gaps = 15/241 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  +++D + V EG  +   C+V    DP   I W  NG+   T   +    +    +
Sbjct: 1098 PAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER- 3813
            + I+     D G Y C A N  G A  + ++T          ++ P+  S      L   
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD-DAPASENTKAPEMKSRRPKSSLPPV 1213

Query: 3814 -GRISDA-------PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
             G  SDA       PK  P  + PP+ I   +   V   E V    +V   +   +   W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQ--PITCTW 1271

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             +  K +      +         L IL    E  G Y     N  G    +  ++    P
Sbjct: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331

Query: 3926 D 3926
            D
Sbjct: 1332 D 1332



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD-FSYVSLD 2834
            F   + ++   EG    F+C +E   DP  ++ WF +++ +     ++  +D     SL 
Sbjct: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I+    +D   YTCKA NS G AT +  L
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 33/104 (31%), Positives = 45/104 (43%), Gaps = 4/104 (3%)

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH-R 2157
            P+E ++    P F +   S E +KE     F C V  I  P +   WF  G  +R     
Sbjct: 404  PMEGQRDSAFPKFESKPQSQE-VKENQTVKFRCEVSGIPKPEVA--WFLEGTPVRRQEGS 460

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 D G   L +L     DSGTY C A+N  G+   + TL+V
Sbjct: 461  IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVA 2036
            P+F    ++ EV E   V     ++ +  P   V W+  G PV++       Y D G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            L +L A   D+GTY C A+NA G+   + +++V+
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVE 505



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 4/84 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY-DFGYV 4031
            P+F ++ QSQ  + E +T KF C+++  G P  +V WF  G P+  +     +Y D G  
Sbjct: 414  PKFESKPQSQ-EVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYG 4055
             +        DSG Y C A+N  G
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQG 494



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/86 (25%), Positives = 41/86 (47%)

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            + Q  AP F ++   ++V EG+ ++L  +    P   I W  +G  +     + +  +G 
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
              ++ I +A   D   Y+C A+N AG
Sbjct: 1152 LCSVSIEKALPEDRGLYKCVAKNDAG 1177



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592
            +K+ + E  S        E +    P F+ T  DL + E S+A F+C++    D    V 
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VV 1841

Query: 3593 WFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            WF + + +      +   ++ G   L I  V   D   YTCKA N  GEAT + +L V+
Sbjct: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 56/240 (23%), Positives = 92/240 (38%), Gaps = 17/240 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP     L++V + EG++   + ++   SD    + W  N K LK+      +      +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV------HSKKSIYLESQH-EGALPRLN 1689
            + I   LPED G Y C A N  G+A  S    V       + K+  ++S+  + +LP + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ--AAHFEARLI--PVGDPKLRVE 1745
              E  +  ++  A        P   MP + I+  E+Q   A     L     G   +   
Sbjct: 1215 GTESDATVKKKPAP----KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W++    I+ S  +   +      L +     E  G YT    N+LG       L V  K
Sbjct: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            E  G  P F   L  + ++ EG +   +C+V   +DP  TI W  NG+ ++       + 
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1148

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +    ++ I     ED G Y C A N  G+A  +C + V
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            P E    S  PKF ++ +S  V+E++ V+F C V     PK  + W+  G  +       
Sbjct: 404  PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEV--SGIPKPEVAWFLEGTPVRRQEGSI 461

Query: 3880 TVY-DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
             VY D G   L +L     DSG Y C A N  G+     T+  ++L
Sbjct: 462  EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERL 507



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 1/100 (1%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNH 320
            P   P  ++  R+ ++ EG+ A+F  ++ G P P V WFK+ Q +  S   +I      +
Sbjct: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             +L + +    D   YT  A N  G    +  L VE+  E
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLTYDGMYHFD 4168
            P F S P +  V+E +  +F C V+G PKP V W L G  +    GS       G ++  
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 4169 IPKTRQYDTG 4178
            + K R  D+G
Sbjct: 474  LLKARTRDSG 483



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 2/111 (1%)

Query: 470  KSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            +S E   Q  L  + +E+  V P F +    L V EG     + +  G P P + W KD 
Sbjct: 1787 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846

Query: 529  VPIIPNPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              I  +   +I + + G  +L I      D A Y C A N  G     A L
Sbjct: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++ ++ EG+     C++    DP   + W  N K ++ +  I  + +    S
Sbjct: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            ++I     ED G+Y C A N  G+
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQ 1178



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 3/113 (2%)

Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHDFGYVALDIASVRA 1110
            + ++ E Q+  F  R E        V W+  G  +      I+ Y D G   L +   R 
Sbjct: 422  SQEVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKART 479

Query: 1111 EDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFV 1163
             DSG Y+  A NA G+   S ++ VE  + ++ +     + +    IE   FV
Sbjct: 480  RDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNKYS 119
           +T   P + + P F    ++   + G +      + G+P P V W R  KA   +   + 
Sbjct: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769

Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSV 159
           +  NE     +L++K++ P   G+Y    +N+ GE  C V
Sbjct: 770 VLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQV 807



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 43/192 (22%), Positives = 68/192 (35%), Gaps = 10/192 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            T+++     +   P F  ++Q    + E +    +CQ++   DP   + W  NGK L   
Sbjct: 1085 TDNEKRSESQGTAPAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTT 1141

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV------Y 4073
                   +    +++     PED G Y C A N  G  E    +     P          
Sbjct: 1142 KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEM 1201

Query: 4074 DSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCR 4133
             S+ PK         E +A+ +  P       KA  PP  +  P+   V  GE      +
Sbjct: 1202 KSRRPKSSLPPVLGTESDATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVRAGESVELFGK 1260

Query: 4134 VTGHPKPRVMWL 4145
            VTG       W+
Sbjct: 1261 VTGTQPITCTWM 1272



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+Q  ++   A+G     + ++  +P   + WT     L +  K+ +  +++    S+
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFII-LSQEGSLCSV 1155

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             I++  P D G Y C A+N  G+A CS  +
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQV 1185



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERD 2980
            ++VEG     + ++E   DP+  + W+ + + + +   F++  D  G  +L + DV   D
Sbjct: 1819 EVVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1876

Query: 2981 SGIYTCKAYNKRGEA 2995
               YTCKA N  GEA
Sbjct: 1877 DAKYTCKAVNSLGEA 1891



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE-FDYVA 1369
            P+F     + E  E   V   C +   G     V WF  G P++        YE      
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L LL     DSG Y+C A+N  G+   S  L+V
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            +D  K      T P F  +++   V E + +  +C+V    DP   I W  NGK L +  
Sbjct: 1085 TDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTK 1142

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
                  +    S+ I     ED G Y C A ND G+
Sbjct: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIV--NGSRYKL 4159
            V+E      P F+S P +VT   G+     C + G P P V WL +G  +    G    L
Sbjct: 712  VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771

Query: 4160 TYDGMYHFDIPKTRQYDTGKIEVI 4183
              + ++   + K + +  G+ E++
Sbjct: 772  QNEDVFTLVLKKVQPWHAGQYEIL 795



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/92 (22%), Positives = 41/92 (44%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F +K+Q   V E ++   + +   +P   I W      +K +    +    +   + I
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
             +   ED  ++  VA+N  G A+CS  + V++
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 3013 TQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASL 3072
            T  P      EK+++ ED  +       ++     P F+   +D+ ++ EG  A ++  +
Sbjct: 1774 TGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKI 1832

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
                D  +V  WF + ++I  S   +  Y   G   L I      D   Y+C+A N  G+
Sbjct: 1833 EGYPDPEVV--WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890

Query: 3132 AEISVKL--ECVDKSKGQ 3147
            A  + +L  E +++ +G+
Sbjct: 1891 ATCTAELIVETMEEGEGE 1908



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 14/127 (11%)

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPK----FITQIQDVTKLVEGQSAHFEARLVPV 3309
            P S     +LES +   Q      + E P     F   I+D+ ++VEG +A F+ ++   
Sbjct: 1777 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGY 1835

Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHD----FGIVILDILYCYEENSGEYECVATNKLGR 3365
             DP+  V WF + + +     ++  +D      ++I D+  C ++++ +Y C A N LG 
Sbjct: 1836 PDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV--CGDDDA-KYTCKAVNSLGE 1890

Query: 3366 DSTKANL 3372
             +  A L
Sbjct: 1891 ATCTAEL 1897



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQSGHRYRTSNDFGFAALDILTVYGED 1913
            ++ E Q+  + C +   P P   V W+  G  V +         D G   L +L     D
Sbjct: 424  EVKENQTVKFRCEVSGIPKPE--VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQ 1937
            SG Y+C A N  GQ   S  L V+
Sbjct: 482  SGTYSCTASNAQGQVSCSWTLQVE 505



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 4/94 (4%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYV 967
            P+F++  + Q  +KE     F  R E  G     V W  +G PV      I  + + G  
Sbjct: 414  PKFESKPQSQ-EVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L +      D+G Y+C A NA GQ + S  L +
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GF 2565
            KP F++ +    E+ EG  A ++ ++    DP +   W+ +   ++    F+  +D  G 
Sbjct: 1808 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEV--VWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I+ V  +D   Y CKA+N  G
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLG 1889



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 3/63 (4%)

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            ++  SW +  E++     A   P F S+     V EG+     C V G P PR+ WLLNG
Sbjct: 495  QVSCSWTLQVERLAVMEVA---PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551

Query: 4149 NTI 4151
              I
Sbjct: 552  QPI 554



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 2232 IEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL-QSAA 2289
            + V+EP   + P F+++ R  T    G++    C +    DP   + +  +GKAL +   
Sbjct: 710  LTVQEPHDGTQPWFISKPRSVTASL-GQSVLISCAI--AGDPFPTVHWLRDGKALCKDTG 766

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS-MTVTAKGSIISESQRPE 2348
             F +  +    +L ++   P  AG+Y +   N +G C+  +S M   +    +   + P 
Sbjct: 767  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 826

Query: 2349 GLEKI 2353
              E +
Sbjct: 827  SCEDL 831



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 4/85 (4%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWF-RNEKLIEDSSRITKTHDFGYV 2434
            P F    Q+   ++E QT  F C +   G P  +V WF     +      I    D G  
Sbjct: 414  PKFESKPQS-QEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
             + +   R  D G Y C ASN  G+
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQGQ 495



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 5/109 (4%)

Query: 628 GEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTS 687
           G+ D  +P  +F    +S    E   + F  R E  G P  ++ W   G  +        
Sbjct: 407 GQRDSAFP--KFESKPQSQEVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462

Query: 688 IFR-FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
           ++   G   L +L    +DSG Y+C A +A G       L V   A +E
Sbjct: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME 511



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 13/120 (10%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL--PSGHRYR 3879
            +EP   T P FI++ +S T    + V   C +    DP   + W R+GK L   +GH + 
Sbjct: 713  QEPHDGTQPWFISKPRSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGH-FE 769

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
             + +    +L +  V    +G+Y     N  GE        C     ++LQN   R + R
Sbjct: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--------CSCQVSLMLQNSSARALPR 821



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTLNDFGFIALDIDYIYARD 3764
            +V E   V F C V   G P   + WF  G P       +    D G   L +     RD
Sbjct: 424  EVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481

Query: 3765 AGEYTCRATNKWGSAT 3780
            +G Y+C A+N  G  +
Sbjct: 482  SGTYSCTASNAQGQVS 497



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 33/88 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P+ ++      VR GE V L  +  GT     TW K    I  +  +++      S L I
Sbjct: 1238 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A+      Y    +N  GS   +  L
Sbjct: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNL 1325



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 1738 GDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            GDP   V WLR+G  + + +     + +     L +K V P  +G Y     N +GE   
Sbjct: 746  GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 805

Query: 1797 SSTLFVQSKASLQLESQHESA 1817
              +L +Q+ ++  L    E A
Sbjct: 806  QVSLMLQNSSARALPRGREPA 826



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
            +E+RSE    +   P F Q L     + EG+    + +V    DP     W +NG  LK 
Sbjct: 1087 NEKRSES---QGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT 1140

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                  + +    ++ I   +  D GLY C A N AG
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAG 1177


>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
            polypeptide kinase isoform 1 protein.
          Length = 1914

 Score =  167 bits (407), Expect = 7e-40
 Identities = 116/431 (26%), Positives = 185/431 (42%), Gaps = 13/431 (3%)

Query: 4389 EIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN 4448
            ++  KA  +   +EG  + S  P F  K Q   V E++  +F  E  G P P + W+ E 
Sbjct: 393  DVVSKAANRRIPMEGQ-RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEG 451

Query: 4449 FPIKNSP-DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
             P++      +++  +    L + +    DS  ++  A N  G   CS  L VE      
Sbjct: 452  TPVRRQEGSIEVYENAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME 511

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567
                V PSF+   ++  V  GQ   L   V GT    + WL NG+ +Q   R+    E G
Sbjct: 512  ----VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTC--EAG 564

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK---PQTKAANAPPE 4624
               L I +A P+D G Y C+A N+ G+  C A   V    +  K +   P   +    P 
Sbjct: 565  VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
             ++ L D  V +G  +  + ++ G P P V W      I+ S+ F   +   +++L I E
Sbjct: 625  FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
             FPED G Y C A+NSAG V   A L V +P        ++  R +    GQ       I
Sbjct: 685  VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744

Query: 4745 TSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                 PT+ WLR+G AL  +T  F+++   +   L++        G +        G+  
Sbjct: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804

Query: 4804 TSAKLVVKSKT 4814
                L++++ +
Sbjct: 805  CQVSLMLQNSS 815



 Score =  109 bits (262), Expect = 2e-22
 Identities = 80/334 (23%), Positives = 136/334 (40%), Gaps = 19/334 (5%)

Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
           G+     + +++R       P  +   ++  + EG D   Q  + G P PR+TW  NGQ 
Sbjct: 494 GQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553

Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
           +  +             L +++    D G YT LAEN  G +  S ++ V     S    
Sbjct: 554 IQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS---- 606

Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           ++S+Y+                K  AP F++   D  V +G       +V+G P PEV W
Sbjct: 607 RKSEYLLPVAP----------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             N  +I++  +          H+L I  V   D+G  TC A N +GE   Q  L V E 
Sbjct: 657 LHNGNEIQESEDFHF-EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715

Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGG 544
                P F+ +  ++    G+ V+++    G P P + W +DG  +  +     +  +  
Sbjct: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775

Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             TL + + +   A  Y+   +N  G  + +  L
Sbjct: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809



 Score =  107 bits (258), Expect = 7e-22
 Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 14/235 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-G 3476
            +AP F +P  N+  ++EG  A FE R+    +P  +V W+ NG+ + +G RF   C   G
Sbjct: 31   EAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 3477 FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIA 3536
               L I   + ED G+Y C A N  G    T  + V+G        QL + +   + K  
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPV---VSKTL 140

Query: 3537 ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
                 +  V+T  P      PP+F T    +++ E     F C++        +V W   
Sbjct: 141  GDRFSASAVET-RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
              PL   +RV      G  +LEI GV Q D G+YTC   N  G+A++S +L ++G
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score =  105 bits (252), Expect = 4e-21
 Identities = 88/328 (26%), Positives = 132/328 (40%), Gaps = 46/328 (14%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEIITTHNHTTLR 324
           PK   KP++ +++E    +F+ ++SG P+P V WF  G  +       E+        L 
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLC 473

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +   +  DSG Y+  A N  G +  S  L VE                         R+ 
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVE-------------------------RLA 508

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
           + E  +AP F  V +D  V EG+     C V G P P +TW +N + I+  Y       E
Sbjct: 509 VME--VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTC--E 562

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE--------------QVVA 490
           +G   L I +    D G  TC+A N  G+ +    + V EK+              +  A
Sbjct: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P F++  S L V +G  V +  +  G P P + W  +G  I  + +      G   +L I
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682

Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARL 578
                 D   Y C A N AG   T+A L
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score =  102 bits (244), Expect = 4e-20
 Identities = 76/245 (31%), Positives = 112/245 (45%), Gaps = 10/245 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDF 1765
            +T+AP F +P +++ + E   A FE R+   G P+ +V W RNG PI +  R L      
Sbjct: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G  +L +  V+ ED G YTC A N  G    +  L V+   + QL     S  + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS--KTLGDRF 144

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             +S  + R  +       P+F T+L G   + EGQ   + C+I   P P  +V W     
Sbjct: 145  SASAVETRPSIWGEC--PPKFATKL-GRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNV 199

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
             LQ   R   S   G   L+I  V  +D G YTC  +N  G+A  S  L++Q  +S  R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 1946 SQHES 1950
               E+
Sbjct: 260  FVRET 264



 Score =  101 bits (242), Expect = 6e-20
 Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 8/219 (3%)

Query: 4404 PVKPSKP--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            PV PSKP  PIF + +   +V +  Q    V+  G P P + W      I+ S DF    
Sbjct: 614  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
              T+  L I++VF ED+  +   A N  G  +  A L V+E    G      P F    +
Sbjct: 674  RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH-DG----TQPWFISKPR 728

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQD 4580
            +V  + GQ V +   + G     V+WL++GK +  D  + ++L+ +  +TL++ +  P  
Sbjct: 729  SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +G+YE +  N  GE  C    ++   + +  P+ +  A+
Sbjct: 789  AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPAS 827



 Score =  100 bits (240), Expect = 1e-19
 Identities = 68/246 (27%), Positives = 114/246 (46%), Gaps = 5/246 (2%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           +   ++ ++ + +      S+     P     PRN  ++EGA A+F+ ++ G P P+VTW
Sbjct: 7   VASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTW 66

Query: 300 FKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-S 357
            +NGQ + +  +  +      T +L +    + D G YT  A N +G    +  L VE S
Sbjct: 67  HRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126

Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
             +   Q   S+ + D       E          P+F        V EG+M RF C++TG
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNE-SGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
           RP P+VTW   +  ++   + ++ V+E +G   L I  V   D GV TC+  N SG+ + 
Sbjct: 187 RPQPQVTWLKGNVPLQP--SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244

Query: 477 QCRLNV 482
              L++
Sbjct: 245 SAELSI 250



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 106/361 (29%), Positives = 152/361 (42%), Gaps = 62/361 (17%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD-FGYV 1502
            P+F ++P+S E V E Q V F C++  +     +V WF  G PV        +++  G  
Sbjct: 414  PKFESKPQSQE-VKENQTVKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYENAGSH 470

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L ++     DSG Y+C A N  G  +VSC  T +              +E++ V+E   
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQG--QVSCSWTLQ--------------VERLAVME--- 511

Query: 1563 KYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKS 1622
                          AP  ++ LK+  + EGQ   F  +         ++ W  N +P++ 
Sbjct: 512  -------------VAPSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQY 556

Query: 1623 GSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHE 1682
                 E    G   L I   LPED GTYTC A NALG+   S    VH KKS     + E
Sbjct: 557  ARSTCEA---GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS---SRKSE 610

Query: 1683 GALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL 1742
              LP        SK             AP+F   + D++V +        ++   G+P  
Sbjct: 611  YLLP-----VAPSK-----------PTAPIFLQGLSDLKVMDGSQVTMTVQV--SGNPPP 652

Query: 1743 RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             V WL NG  I+ S            +L ++ V PED+GTYTC A N  GE  T + L V
Sbjct: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712

Query: 1803 Q 1803
            Q
Sbjct: 713  Q 713



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 19/225 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P+F L  +N+ +  G   + + +V G     V W +NG+ +    R  +     GT++L+
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP---------------QTK 4617
            I   + +D GKY C A N +G  +   E  V     K   +P               +T+
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4618 AA---NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             +     PP+    L   +V EGQ   FSCKI G+P P V W KG+  ++PS    +S  
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
                 L I     +D G Y C+  N +G+ +++A+L +   D A+
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 166/703 (23%), Positives = 277/703 (39%), Gaps = 94/703 (13%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            FI    N+  KEG    FE  V    +P  ++ W  N +P+ SG R+          SL 
Sbjct: 35   FILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I   +EED G YTC+ATN  G+   +  L   G     F  Q  Q        ++   + 
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSAS- 147

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
             A   RPS+   E P P++   +     + EGQ+     ++  +  P  ++ W      L
Sbjct: 148  -AVETRPSIWG-ECP-PKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPL 201

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD----NLI 3010
            +  +R  ++   G   L++  V + D G+YTC   N  G+A  S+ +     D    + +
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261

Query: 3011 ERTQHPKGTEGLE---------KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDIS 3061
              T+        E         K+ +LE + + +    P    G PP             
Sbjct: 262  RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRG-GSPP--WAANSQPQPPR 318

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK-----TT 3116
            E ++   + S   T  Q+ V++   +  T++A+       A G+ VL   G +       
Sbjct: 319  ESKLESCKDS-PRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP 377

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQK----PRFTTHIQNIEGLKDGQSAHFECT 3172
               T+  R      Q  +S         +GQ+    P+F +  Q+ E +K+ Q+  F C 
Sbjct: 378  RPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE-VKENQTVKFRCE 436

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHST-RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            V  +  P+  + W+  G P+R     I+   + G   L +   +  DSG Y C A N  G
Sbjct: 437  VSGIPKPE--VAWFLEGTPVRRQEGSIEVYENAGSHYLCLLKARTRDSGTYSCTASNAQG 494

Query: 3232 EDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDV 3291
            +      ++C         +LQ + LA            +  PS        F + ++D 
Sbjct: 495  Q------VSCSW-------TLQVERLA----------VMEVAPS--------FSSVLKDC 523

Query: 3292 TKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEEN 3351
              ++EGQ   F  +      P  ++ W  NG+ + +    R+  + G+  L I     E+
Sbjct: 524  A-VIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPED 577

Query: 3352 SGEYECVATNKLGRDSTKA----NLKCTSKENLILDSQLPRGMEG-----GLEKLQTLED 3402
             G Y C+A N LG+ S  A    + K +S+++  L    P          GL  L+ ++ 
Sbjct: 578  HGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDG 637

Query: 3403 SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLT 3445
            S V    T   +  G  P   + L N   ++E E+ HFE R T
Sbjct: 638  SQV----TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 18/246 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-VKTINDFGFVI 3616
            P F   P +L + E ++A FE R+    +   +V W  NG+P+ +G R +      G   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V++ D G YTC+ATN  G   V+ +L V+G        QL     S T   +   
Sbjct: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSA 146

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
              +  R  I  E     PP+F  ++   + V EG    F C++   G P  ++ W     
Sbjct: 147  SAVETRPSIWGEC----PPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNV 199

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC----SAKRD 3792
            P    +RV      G   L+I  +   D G YTC   N  G A+ +A+++     SA R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 3793 IVLESQ 3798
             V E++
Sbjct: 260  FVRETK 265



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 64/224 (28%), Positives = 96/224 (42%), Gaps = 25/224 (11%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F   +K+  V EG    L+ ++     P  R+ W  NG+P+Q     ++T + G   L
Sbjct: 514  PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 568

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             I  A  ED GTY C A NA+G+   ++ V V  K                +   K E  
Sbjct: 569  HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK----------------KSSRKSEYL 612

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
             P+   +P   P+FL  L+   +LK  D +     V+   +P   + W HNG +I+    
Sbjct: 613  LPVAPSKP-TAPIFLQGLS---DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +         +L I   + ED+GTY C+A N  GE      L V
Sbjct: 669  FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 16/225 (7%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGFIALDIDYIYA 3762
            N+ + EG    F+ RV   G P  ++ W  NG+P  +G R +      G  +L I  ++ 
Sbjct: 41   NLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS-DAPK 3821
             D G+YTC ATN  G+   T ++T           QL Q +  + + +    R S  A +
Sbjct: 99   EDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGD----RFSASAVE 150

Query: 3822 EEPIV--STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              P +    PPKF T++    V+E +  RF C++  +  P  ++ W +    L    R  
Sbjct: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVS 208

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
                 G   L+I  V  +D G Y C  VN  G+    A +S + L
Sbjct: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 18/242 (7%)

Query: 2899 RRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS 2958
            R  S+P TE   P +I+P      + EG     EG+V  +  P+ ++ W+ NG+ +  G 
Sbjct: 23   RVDSMPLTE--APAFILP-PRNLCIKEGATAKFEGRV--RGYPEPQVTWHRNGQPITSGG 77

Query: 2959 RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK 3017
            RF L     G  +L +  V+E D G YTC+A N  G      TV  T + +  ++   P 
Sbjct: 78   RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPV 135

Query: 3018 GTEGLEKIQNLEDSLRKEPGQQPDDDTGR-PPEFTTVFKDIVDISEGQIAHYEASLIPTG 3076
             ++       L D       +      G  PP+F T    +V + EGQ+  +   +  TG
Sbjct: 136  VSK------TLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKI--TG 186

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
                 + W      ++ S R+      GM VLEI G    D G Y+C   N  G+A +S 
Sbjct: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246

Query: 3137 KL 3138
            +L
Sbjct: 247  EL 248



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 70/260 (26%), Positives = 115/260 (44%), Gaps = 36/260 (13%)

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            EKR + +G    P+F    Q+V+V  G+ + L  +V+   P  + W  NGK ++   +  
Sbjct: 1088 EKRSESQG--TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFI 1144

Query: 4562 ILEEDGTYTLLILE-AYPQDSGKYECVAINSAGEARCDAECVV-SLPATKDKPKPQTK-- 4617
            IL ++G+   + +E A P+D G Y+CVA N AG+A C  +  V   PA+++   P+ K  
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204

Query: 4618 ----------------------AANAPP------EIIEPLKDKIVAEGQAIEFSCKIVGK 4649
                                  A   PP      +II+  +D+ V  G+++E   K+ G 
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
               T  W K  K I+ S++ ++  + +   L I  A  E  G Y  +  N  G       
Sbjct: 1265 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1324

Query: 4710 LKVT-QPDQADNLPALTPLR 4728
            L V  +PD     P  + +R
Sbjct: 1325 LTVVDKPDPPAGTPCASDIR 1344



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 62/249 (24%), Positives = 111/249 (44%), Gaps = 12/249 (4%)

Query: 617 HVERARPYIPPGEEDRV--YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLK 674
           H+ +    + P   D +     P FI+P +++   EG    FE R+   G P  ++ W +
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHR 68

Query: 675 NGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
           NGQ I +  RF       G  SL + +++ +D G+YTC A + +G  +    + +T   +
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV--TVELTVEGS 126

Query: 734 IERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQ 793
             +    P   + +      S  + + SI  +    P+F   L  +  ++EG+   F  +
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECP--PKFATKLGRV-VVKEGQMGRFSCK 183

Query: 794 LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           +T    P  +V W K   P+  S+R++     G   L I  +  +D G YT   VN  G+
Sbjct: 184 IT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241

Query: 854 AISTASIRV 862
           A  +A + +
Sbjct: 242 ASMSAELSI 250



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 65/228 (28%), Positives = 99/228 (43%), Gaps = 14/228 (6%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            +T  P F+  P+++  + EG    FE ++    +   +V W +NGQP+T G RF      
Sbjct: 29   LTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGI 85

Query: 1500 -GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI-QV 1557
             G  +L I  +  ED G YTC A N  G  +V+  LT         S   + G   + + 
Sbjct: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG------SFAKQLGQPVVSKT 139

Query: 1558 LEDRSKYHRTDMVDEVTTQAPI-CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            L DR      +    +  + P    T L  V +KEGQ   F  ++        +V W   
Sbjct: 140  LGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            N PL+  +R + +   G   L+I     +D G YTC  +N  G+A  S
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 15/244 (6%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF- 964
            T+ P F  P ++ + IKEG  A FE R+   G    +V W ++G+P+ +  R        
Sbjct: 30   TEAPAFILPPRN-LCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
            G  +L I +V   D G YTC A N  G    +  LT+  +     +   P   + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRF 144

Query: 1025 DASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEWYFN 1082
             AS  +  T   +     P+F   L G   + EGQ   F  ++   PQ  +T    W   
Sbjct: 145  SAS--AVETRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVT----WLKG 197

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
               +  + R+      G   L+I  V  +D GVYT +  N +G+A +SA ++++   S +
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257

Query: 1143 TSSI 1146
             S +
Sbjct: 258  RSFV 261



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 80/317 (25%), Positives = 135/317 (42%), Gaps = 33/317 (10%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA-FGMVVLEILGTKTTD 3117
            ++ E Q   +   +  +G     + WF  G  +        VY   G   L +L  +T D
Sbjct: 424  EVKENQTVKFRCEV--SGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLCLLKARTRD 481

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            SGTYSC A+N  GQ   S  L+    +  +  P F++ +++   + +GQ    +C+V   
Sbjct: 482  SGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDC-AVIEGQDFVLQCSVRGT 540

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P  +I W  NGQP++++   ++  + G   L I      D G Y C A N  G+    
Sbjct: 541  PVP--RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCS 595

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +  + K      S + + L  +             PS P+A  P F+  + D+ K+++
Sbjct: 596  AWVTVHEK----KSSRKSEYLLPV------------APSKPTA--PIFLQGLSDL-KVMD 636

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV-ILDILYCYEENSGEY 3355
            G       ++    +P  +V W +NG ++     +  F   G    L I   + E++G Y
Sbjct: 637  GSQVTMTVQV--SGNPPPEVIWLHNGNEIQESEDFH-FEQRGTQHSLCIQEVFPEDTGTY 693

Query: 3356 ECVATNKLGRDSTKANL 3372
             C A N  G   T+A L
Sbjct: 694  TCEAWNSAGEVRTQAVL 710



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 39/107 (36%), Positives = 57/107 (53%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            E +   +  + P F K  +D +V EG   RFDC++ G P PEV WF +D+ IR+  + +I
Sbjct: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
              +E GN +L+I++V   D    TC A N  GE      L V   E+
Sbjct: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 11/215 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGI 2714
            EG     E +V    +P  ++ W +NG  +T+G R        G  +L I+++  +D G 
Sbjct: 46   EGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2715 YTCKATNLLGEAVSTASIKIEDRHWL-LGESLHPDSL-DRIGALXXXXXXXXXXXXXXXX 2772
            YTC+ATN  G    T  + +E      LG+ +   +L DR  A                 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA----SAVETRPSIWGEC 159

Query: 2773 XXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS 2832
               F + L  +V KEG    F C +     P  ++ W   N PL    R   +       
Sbjct: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQV 217

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            L+I    ++D G+YTC   N  G A+ S  L   G
Sbjct: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 12/194 (6%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGE 4045
            E  T KFE ++   G P  +V W  NG+P+    RF       G  ++    V+ ED G+
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 4046 YLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEES 4105
            Y C ATN  G  +    +   G     +  QL + + S        AS   T   +  E 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE- 158

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGM 4164
               CPP F +    V V+EG+  RF C++TG P+P+V WL     +   +R  ++  +GM
Sbjct: 159  ---CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGM 215

Query: 4165 YHFDIPKTRQYDTG 4178
               +I    Q D G
Sbjct: 216  QVLEIHGVNQDDVG 229



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 69/232 (29%), Positives = 101/232 (43%), Gaps = 27/232 (11%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V+  AP F+  +KD  V E Q   F  +    G P  R+ WL NG PI+ + R T   + 
Sbjct: 509  VMEVAPSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EA 563

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G   L+++   PED GTYTC A N LG+   S+ + V  K S                  
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS------------------ 605

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             S + +    V  +   AP F+  L+   K+ +G       ++   P P   V W  NG 
Sbjct: 606  -SRKSEYLLPVAPSKPTAPIFLQGLS-DLKVMDGSQVTMTVQVSGNPPP--EVIWLHNGN 661

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             +Q    +         +L I  V+ ED+G YTC+A N+ G+  +   L VQ
Sbjct: 662  EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 14/252 (5%)

Query: 1970 DDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            D   + E P F  P +N  + EG     E  +    +P  +V W+ NG+P+  G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLD 82

Query: 2030 YDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYL-DTLDEQRLKK 2087
                G  +L I   + ED G Y C+ATN  G    T  + V+      L   +  + L  
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                   E    I  E P   P F T L  +  +KEG    F C++     P +T  W  
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKITGRPQPQVT--WLK 196

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG---- 2203
                ++   R   +   G   L+I     +D G Y C   N  G+A  +  L + G    
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256

Query: 2204 HRNIILDTQHPN 2215
            +R+ + +T+  N
Sbjct: 257  NRSFVRETKATN 268



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 74/305 (24%), Positives = 117/305 (38%), Gaps = 21/305 (6%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P FE   ++    +    KF  ++ G P P V+W  +  P V   + S+   E  G   L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTP-VRRQEGSIEVYENAGSHYL 472

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            + +    D G Y+CTA N  G+  CS  +Q E               +  +  +E + +
Sbjct: 473 CLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCA-VIEGQDF 531

Query: 192 GTQGYT--TEQSRQT-----QKVAYTNGTDHSSTDDFKV------DTFEYRLLREVSFRE 238
             Q     T   R T     Q + Y   T  +   +  +      D   Y  L E +  +
Sbjct: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591

Query: 239 SITKRYVGESDVQISTEIDRSLGPVSP-----PKIAQKPRNSKLQEGADAQFQVQLSGNP 293
                +V   + + S + +  L PV+P     P   Q   + K+ +G+     VQ+SGNP
Sbjct: 592 VSCSAWVTVHEKKSSRKSEYLL-PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
            P V W  NG  +  S            +L ++     D+G YT  A N  G + T   L
Sbjct: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710

Query: 354 AVESP 358
            V+ P
Sbjct: 711 TVQEP 715



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 61/225 (27%), Positives = 102/225 (45%), Gaps = 13/225 (5%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P    P F+   R    + EG TA FE +V    +P  ++ ++ NG+ + S  RF +   
Sbjct: 28   PLTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCG 84

Query: 2297 F-GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRE 2355
              G  SL I     ED G+Y+ +A N  G     +++ +T +GS   +  +P   + + +
Sbjct: 85   IRGTFSLVIHAVHEEDRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2356 LESAEPFK-RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
              SA   + RP I        P F   L  +  ++EGQ   F C++   G P  +V W +
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKI--TGRPQPQVTWLK 196

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                ++ S+R++ +   G   + I  V  +D GVY C   N  G+
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 26/240 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++ P F    +   + E   A+FE    G P P + W+R   PI +   F +      + 
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG----------------- 4509
             L+I  V  ED   +   A N  G  + +  L VE    +  G                 
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149

Query: 4510 -------GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                   G  PP F      V V  GQ+ R   K+TG     V WLK    +QP  R  +
Sbjct: 150  ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE-CVVSLPATKDKPKPQTKAANA 4621
             E++G   L I      D G Y C+ +N +G+A   AE  +  L +       +TKA N+
Sbjct: 210  SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 110/491 (22%), Positives = 182/491 (37%), Gaps = 27/491 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+ P  N   + EG     E R+   G P  +V W  NG+ +T G RF          
Sbjct: 33   PAFILPPRNLC-IKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 1237 LDIIHAT-SADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
              +IHA    D G+YT  A N  G+   + +   +E S      Q  Q +    L +  +
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVT-VELTVEGSFA---KQLGQPVVSKTLGDRFS 145

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                + R  I     P+F+  L  +   EG      C++   G    +V W     P++ 
Sbjct: 146  ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQP 203

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              R   + +     L++  V  +D GVYTC   N  G+A  S  L +       L+S + 
Sbjct: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG-----LDSANR 258

Query: 1416 SGLEKIQYLEDTSRYKKTDIID-ESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            S + + +      R + T++I  ES         + K+  +   G    +    +P    
Sbjct: 259  SFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
              K+E  K+  P T      P+      ++ +     +         V     +E     
Sbjct: 319  ESKLESCKD-SPRTAPQ--TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA 375

Query: 1535 TCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
              R  T   R    + GL    V+  ++   R  M  +  +  P   +  ++ E+KE Q 
Sbjct: 376  PPRPATFPTR----QPGLGSQDVV-SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET-NNFGFVALDIMSCLPEDSGTYTCR 1653
              F   +  +     +V W+    P++      E   N G   L ++     DSGTY+C 
Sbjct: 431  VKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYENAGSHYLCLLKARTRDSGTYSCT 488

Query: 1654 AINALGEAVTS 1664
            A NA G+   S
Sbjct: 489  ASNAQGQVSCS 499



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 10/224 (4%)

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
            + + D  C      T D  K ++++    P   + L+D  VAEG+ +   C++   P  T
Sbjct: 1070 DVKNDVNCKRGHAGTTDNEK-RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W    K +K +K+  +S+     ++ I +A PED G YKCVA N AG+   + ++ V 
Sbjct: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD 1188

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQ--ITSKIKPTIQWLREGALIPET---PDFQ 4768
                ++N  A   ++        P    T+   T K KP  +   + A+ P+    P+ Q
Sbjct: 1189 DAPASENTKA-PEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  G  +V L G      T   TC       Q++ S  + V++
Sbjct: 1248 KVRAG-ESVELFGKV--TGTQPITCTWMKFRKQIQESEHMKVEN 1288



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 67/227 (29%), Positives = 97/227 (42%), Gaps = 27/227 (11%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F + L     + EGQ    +C +   P P  R+ W  NG+ +Q     R++ + G A
Sbjct: 513  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 566

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
             L I     ED G YTC A N LGQ   S  + V  K+S            K +YL   +
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----------SRKSEYLLPVA 616

Query: 1963 RYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ 2022
              K            P F + + + +V +G  V +  T+    +P   V W  NG  +Q+
Sbjct: 617  PSKPTA---------PIFLQGLSDLKVMDGSQVTM--TVQVSGNPPPEVIWLHNGNEIQE 665

Query: 2023 GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
               F         +L I   + EDTGTY C+A N+ GE  T + + V
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 1/98 (1%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLR 4681
            P   + ++D  V EG A  F CKI G P P V W+K D+ I+ S++FQ+    D   +L 
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
            IS+   +D+  Y C A NS G  T  A+L V   ++ +
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 69/245 (28%), Positives = 100/245 (40%), Gaps = 29/245 (11%)

Query: 1298 TKQVREDITVMQ-APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            T QV E + VM+ AP FS  L +   +EG +  L+C ++  G    R+ W  NG+PI+  
Sbjct: 501  TLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA 557

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
               R   E     L +    PED G YTC A N LG+   S  + V  KK          
Sbjct: 558  ---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK---------- 604

Query: 1417 GLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL 1476
               K +YL   +  K T          P F+     ++ V++G  V    ++    +   
Sbjct: 605  SSRKSEYLLPVAPSKPT---------APIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPP 652

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            +V W  NG  +     F         +L I ++  ED+G YTC A N  G       LT 
Sbjct: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712

Query: 1537 RSTTD 1541
            +   D
Sbjct: 713  QEPHD 717



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 71/270 (26%), Positives = 105/270 (38%), Gaps = 23/270 (8%)

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G V  VA +   +T+     + ++   +  AP F+     L ++EG       R  G P 
Sbjct: 2   GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 520 PRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P++TW ++G PI       +     G  +L I      D   Y C A N +G     AR 
Sbjct: 62  PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG-----ARQ 116

Query: 579 YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQ 638
                       K+L  P  +K                 VE  RP I  GE      PP+
Sbjct: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSASA-------VE-TRPSI-WGE-----CPPK 162

Query: 639 FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDM 698
           F   L  V   EG    F  +I   G P  ++ WLK    ++ S+R +   + G   L++
Sbjct: 163 FATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220

Query: 699 LSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +N  D G YTC  V+ +G A   A L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 1/93 (1%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYT 4570
            V P F+ T +++ V  G   R D K+ G    +V W K+ + ++     +I  +EDG  +
Sbjct: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            L+I +    D  KY C A+NS GEA C AE +V
Sbjct: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 64/250 (25%), Positives = 102/250 (40%), Gaps = 11/250 (4%)

Query: 3125 ATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKI 3183
            A++   +  +SV    VD     + P F    +N+  +K+G +A FE  V    +P  ++
Sbjct: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QV 64

Query: 3184 EWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             W+ NGQP+    R        G   L I      D G+Y C A N  G    + T+   
Sbjct: 65   TWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELT 122

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +G    +  QP     + +  S    + + PS     PPKF T++  V  + EGQ   F
Sbjct: 123  VEGSFAKQLGQPVVSKTLGDRFSASAVETR-PSIWGECPPKFATKLGRVV-VKEGQMGRF 180

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
              ++     P  +V W      L    R       G+ +L+I    +++ G Y C+  N 
Sbjct: 181  SCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238

Query: 3363 LGRDSTKANL 3372
             G+ S  A L
Sbjct: 239  SGKASMSAEL 248



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
            +K++  ED S+       E   +  P F   +    ++ EG +A ++C+IE YPDP   V
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPE--V 1840

Query: 1879 EWYFNGKVLQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             W+ + + ++    ++   D  G  +L I  V G+D  +YTCKA+N+LG+A  +  L V+
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900

Query: 1938 SKE 1940
            + E
Sbjct: 1901 TME 1903



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/243 (23%), Positives = 99/243 (40%), Gaps = 35/243 (14%)

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-- 425
           S +I+ T       R++      AP F+   ++  + EG   +F+ RV G P P+VTW  
Sbjct: 9   SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68

Query: 426 ----------FINDRQIRDDYN---HKILVNESGNHALMITN--------VTLSDSG--- 461
                     F+ D  IR  ++   H +   + G +    TN        V L+  G   
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128

Query: 462 ------VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
                 VV+    ++   +A + R ++  +     PKF  +   + V+EG+    + +  
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGE---CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           G P P++TW K  VP+ P+  + +    G   L+I      D   Y C   N +G  +  
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245

Query: 576 ARL 578
           A L
Sbjct: 246 AEL 248



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/217 (26%), Positives = 91/217 (41%), Gaps = 14/217 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGL 2580
            EG  A +E RV   G P  +  W+ NG  +  G RF       G  +L I++V   D G 
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2581 YMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQI--QLKEAAMNKVPEMFVDTGV 2638
            Y C+A N +G                  Q  +P   + +  +   +A+   P ++ +   
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFA--KQLGQPVVSKTLGDRFSASAVETRPSIWGEC-- 159

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
               P F T L     + EGQ      ++  R  P  ++ W K  V L   AR+  +   G
Sbjct: 160  --PPKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNG 214

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            +  L I+ +  DD G+YTC   N  G+A  +A + I+
Sbjct: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 6/119 (5%)

Query: 1415 PSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            P   EK++  ED S+     + +E   +KP F    + +E V+EG    F+CK+E   D 
Sbjct: 1780 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1838

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
              +V WFK+ Q +     F+  +D  G  +L I D+  +D   YTC+AVN +G  E +C
Sbjct: 1839 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATC 1893



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 6/103 (5%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            + EE+P  +P F   +  LE + EG  A F+C++E   DP +   WF + Q IR    ++
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQ 1856

Query: 2160 TTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              +D  G  +L I     +D   Y CKA N LGEA  TCT ++
Sbjct: 1857 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCTAEL 1897



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 67/267 (25%), Positives = 104/267 (38%), Gaps = 22/267 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F++V KD   I EGQ    + S+   G     I W  NG+ I+ +   R+    G+  
Sbjct: 514  PSFSSVLKDCAVI-EGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK-----------PRFTTHIQ 3156
            L I      D GTY+C A N  GQ   S  +   +K   +K           P     +Q
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             +  LK    +    TV    +P  ++ W HNG  ++ S             L I     
Sbjct: 628  GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687

Query: 3217 HDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPST 3276
             D+G Y C A+N  GE  T+A +          +  QP  ++K R + +  G        
Sbjct: 688  EDTGTYTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWFISKPRSVTASLGQSVLISCA 743

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFE 3303
             + +P   +  ++D   L +  + HFE
Sbjct: 744  IAGDPFPTVHWLRDGKALCK-DTGHFE 769



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 53/219 (24%), Positives = 93/219 (42%), Gaps = 30/219 (13%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLR 4681
            P  I P ++  + EG   +F  ++ G P P V W++ G  +    ++         ++L 
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4682 ISEAFPEDEGDYKCVAYNSAG--RVTVAAKLK------VTQPDQADNL------------ 4721
            I     ED G Y C A N +G  +VTV   ++      + QP  +  L            
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4722 PAL---------TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
            P++         T L  +VV EGQ  +F  +IT + +P + WL+    +  +    +  +
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                VL I    ++D G +TC     +G+   SA+L ++
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 59/227 (25%), Positives = 96/227 (42%), Gaps = 27/227 (11%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++ AP F++ LK    ++EGQ   L+  V  R  P  +I W  NG  +      +ST + 
Sbjct: 510  MEVAPSFSSVLKDC-AVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 563

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI-EDRHWLLGESLHPDSLDRIGAL 2756
            G+  L I     +D G YTC A N LG+   +A + + E +     E L P +  +  A 
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA- 622

Query: 2757 XXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL 2816
                              +F+  L+++   +G  +     V+ S +P  ++ W  N   +
Sbjct: 623  -----------------PIFLQGLSDLKVMDGSQV--TMTVQVSGNPPPEVIWLHNGNEI 663

Query: 2817 PSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +      +  SL I   + ED+G YTC+A NS G   T   L
Sbjct: 664  QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 62/232 (26%), Positives = 94/232 (40%), Gaps = 28/232 (12%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   LK    ++EGQ   F  +   +      + W  NG+ I  A   ++  + G   
Sbjct: 514  PSFSSVLKDC-AVIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I     ED G YT +A NA G+   SA +TV  + S                  +S++
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----------------RKSEY 611

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            + P   +     + P+F+Q LS+   V +G  + +  ++   G+P   V W HNG  +  
Sbjct: 612  LLP---VAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQE 665

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
               F         +L I      DTG YT  A N  G   T A++ V E  D
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 5/143 (3%)

Query: 2319 AINALGHCTS-AISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
            A+ A+G  +S A+   ++ + S       P   EK+   E         + E     +P 
Sbjct: 1751 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1810

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSM 2436
            F++ +++++ + EG  A FDC++    DP  +V WF++++ I +S      +D  G  S+
Sbjct: 1811 FSKTIRDLE-VVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867

Query: 2437 TISHVRDEDEGVYMCRASNLLGE 2459
             IS V  +D+  Y C+A N LGE
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGE 1890



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 54/227 (23%), Positives = 89/227 (39%), Gaps = 11/227 (4%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            + EG+ L L+ QV   +DP   I W  NGK L+      L+ +    ++ +      D G
Sbjct: 1109 VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166

Query: 2983 IYTCKAYNKRGEAFTSSTVYC----TSKDNLIERTQHPKGTEGLEKIQNLED--SLRKEP 3036
            +Y C A N  G+A  S  V       S++      +  +    L  +   E   +++K+P
Sbjct: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
              +       PP+    F +   +  G+       +  TG Q +   W    K I+ S  
Sbjct: 1227 APKTPPKAAMPPQIIQ-FPEDQKVRAGESVELFGKV--TGTQPITCTWMKFRKQIQESEH 1283

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            ++   +     L IL  +    G Y+    NK G  +  V L  VDK
Sbjct: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 44/140 (31%), Positives = 66/140 (47%), Gaps = 5/140 (3%)

Query: 4374 GDKEITRKITSTETTE-IEHKAQTQERVVEGPV--KPSKPPIFTKKMQPCRVFEHEQARF 4430
            G K  T   TS    E +E +    +  +E     KP   P F+K ++   V E   ARF
Sbjct: 1769 GRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARF 1828

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489
            + + +G P P + W++++  I+ S  FQI +       LII  V  +D A +   A N  
Sbjct: 1829 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1888

Query: 4490 GTAKCSANLVVEEKRRQGRG 4509
            G A C+A L+V E   +G G
Sbjct: 1889 GEATCTAELIV-ETMEEGEG 1907



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 67/228 (29%), Positives = 98/228 (42%), Gaps = 28/228 (12%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F + +KD  ++ EG    F  +    G    R+ WL +G+P++ + R T     G   
Sbjct: 514  PSFSSVLKD-CAVIEG--QDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAE 567

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I+     D G YTC A NA+GQ + SA +T+  KK             K +YL   + 
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKSEYLLPVAP 617

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
             SK T         P FL  L    K+++G       +V    +    V W  NG +I  
Sbjct: 618  -SKPT--------APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 665

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            +            +L I  V  ED+G YT  A N+AGE +  A +TV+
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/155 (30%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 710  TCRAVSATGVAETKAVLH-VTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ 768
            T  AV A G   + A++  ++ R +   +   P   + ++  ED S+   +   EE+   
Sbjct: 1748 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1807

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827
            +P F + ++DL E+ EG  A F+ ++    DP   V W+KD + I  S      ++  G 
Sbjct: 1808 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             SL I  +  +D   YT +AVN LGEA  TA + V
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 46/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 983  TCRAYNAIGQATTSANLTIVT-KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            T  A  AIG+ ++ A ++ ++ +K        P   EK++  ED S+       E K   
Sbjct: 1748 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1807

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGY 1100
            KP F   ++   ++VEG +A F+ ++E   D    V W+ + + I  +   Q  Y + G 
Sbjct: 1808 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPD--PEVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             +L I+ V  +D   YT  A N+ GEA  +A + VET
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1901



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F +  ++    +G  A+F+ K+ G P P V W +    + E   + + Y+E  G+ SL
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1867

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            +I  +   D+ +YTC A N  GEA C+
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCT 1894



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 20/239 (8%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P FI   ++  ++E    +FE RV    +P  ++ W+RNG+ + SG R+     + G  S
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  V+ ED G+Y C A N  G    + T+      ++ ++    + + +      +  
Sbjct: 91   LVIHAVHEEDRGKYTCEATN--GSGARQVTV------ELTVEGSFAKQLGQPVVSKTLG- 141

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
               ++++    T   ++    + PP+F T++  +  + E +  +F C++   G P  +V 
Sbjct: 142  --DRFSASAVETRPSIWG---ECPPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVT 193

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W     PL    R +     G   +    V  +D G Y C   N  G     A +   G
Sbjct: 194  WLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 12/238 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F   ++D+ VAE +    + ++    DP   + W  NG  ++ +  +    +    +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-------QSKASLQLESQHESALQKIQ 1822
            ++++   PED G Y C A N+ G+A  S  + V        +KA      + +S+L  + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1823 QLEDSSRYQRREDVEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
              E  +  +++   +     A P  I Q     K+  G+S     ++     P +   W 
Sbjct: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG-TQP-ITCTWM 1272

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
               K +Q     +  N    + L IL    E  G YT    N LG   + + L V  K
Sbjct: 1273 KFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 3/130 (2%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +L   ED S+    +  +E     P F+  ++D+ V E  AA F+ ++    DP+  V W
Sbjct: 1785 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1842

Query: 1747 LRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             ++   I  S      +D  G  +L +  V  +D   YTC+A+N LGEA  ++ L V++ 
Sbjct: 1843 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902

Query: 1806 ASLQLESQHE 1815
               + E + E
Sbjct: 1903 EEGEGEGEEE 1912



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 38/120 (31%), Positives = 62/120 (51%), Gaps = 5/120 (4%)

Query: 1953 EKIQYLEDDSR-YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
            EK++  ED S+ +  AV ++   V KP F K I++ EV EG     +  +    DP   V
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHV-KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EV 1840

Query: 2012 EWYCNGRPVQQGHRFKTTYDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             W+ + + +++   F+  YD  G  +L I     +D   Y CKA N++GEA  T+ + V+
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 70/311 (22%), Positives = 117/311 (37%), Gaps = 34/311 (10%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            ++EGQ   L+  V  +  P  +I W  NG+ ++     + T + G   L + D    D G
Sbjct: 525  VIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHG 579

Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDD 3042
             YTC A N  G+   S+ V           T H K +    K + L      +P      
Sbjct: 580  TYTCLAENALGQVSCSAWV-----------TVHEKKSS--RKSEYLLPVAPSKP------ 620

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
                 P F     D+  +   Q+     ++  +G+    + W +NG  I+ S        
Sbjct: 621  ---TAPIFLQGLSDLKVMDGSQVT---MTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
                 L I      D+GTY+C A N  G+      L   +   G +P F +  +++    
Sbjct: 675  GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA-S 733

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST-RIKTVSDFGFVVLDIAYTQNHDSGE 3221
             GQS    C +    DP   + W  +G+ +   T   + + +     L +   Q   +G+
Sbjct: 734  LGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791

Query: 3222 YVCRAYNKYGE 3232
            Y     N+ GE
Sbjct: 792  YEILLKNRVGE 802



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 61/212 (28%), Positives = 85/212 (40%), Gaps = 26/212 (12%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG     +C V     P +T  W  NGQ I+     R+T + G   L I     ED GTY
Sbjct: 527  EGQDFVLQCSVRGTPVPRIT--WLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 581

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPP 2242
             C A N LG+   +C+  V  H             +  R+ E       + V   K + P
Sbjct: 582  TCLAENALGQV--SCSAWVTVHEK-----------KSSRKSEYL-----LPVAPSKPTAP 623

Query: 2243 RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
             F+  L     V +G       QV    +P   + + HNG  +Q +  FH        SL
Sbjct: 624  IFLQGL-SDLKVMDGSQVTMTVQVSG--NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             IQ   PED G Y+ +A N+ G   +   +TV
Sbjct: 681  CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 55/235 (23%), Positives = 92/235 (39%), Gaps = 14/235 (5%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F + L ++   EG  + L+C++    D    + W  NGK +KT      + E    +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV------IAKKDLILESQHP-SGLEKIQ 1422
            + +    PED G+Y C A N  G+A  SC + V         K   ++S+ P S L  + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1423 YLEDTSRYKKTDI--IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEW 1480
              E  +  KK           + P+ +  P+  + V  G+ V    K+       +   W
Sbjct: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKV--TGTQPITCTW 1271

Query: 1481 FKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             K  + +      +  +      L I+    E  G YT    N +G+ +    LT
Sbjct: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1326



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 8/123 (6%)

Query: 43  HFTRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPV 102
           H ++   +   S  D  P+T   P    PP      +N    +G  AKFEG++RG P P 
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEA-PAFILPP------RNLCIKEGATAKFEGRVRGYPEPQ 63

Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           V+W R   P+    ++ +    + G  SL+I  +   D G+YTC A N  G    +V + 
Sbjct: 64  VTWHRNGQPITSGGRFLLDCGIR-GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122

Query: 163 PEG 165
            EG
Sbjct: 123 VEG 125



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 63/218 (28%), Positives = 91/218 (41%), Gaps = 28/218 (12%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F + L+    V EG+    +C V     P  RI +  NG+ +Q A     T + G   
Sbjct: 514  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYARS---TCEAGVAE 567

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L IQ  +PED G Y+  A NALG  + +  +TV  K S    S++ E             
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSE------------- 610

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            +  P  P   T   P+F Q L ++  + +G       ++   G+P  +V W  N   I++
Sbjct: 611  YLLPVAPSKPT--APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 665

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S            S+ I  V  ED G Y C A N  GE
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 58/243 (23%), Positives = 97/243 (39%), Gaps = 17/243 (6%)

Query: 258  RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            RS    + P   QK ++  + EG     Q Q+S +P   + W  NG+ L  + K  I++ 
Sbjct: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1148

Query: 318  HNHT-TLRVRNTQKSDSGHYTLLAENPNG-----CIVTSGYLAVESPTESYVQDQRSQYI 371
                 ++ +      D G Y  +A+N  G     C VT         T++     R    
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208

Query: 372  TDTQQRETEERIEISEK---------ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            +      TE    + +K         A+ PQ ++  +D+ V  G+      +VTG     
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             TW    +QI++  + K+  +E+G+  L I        G  T +  NK G    Q  L V
Sbjct: 1269 CTWMKFRKQIQESEHMKVENSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327

Query: 483  IEK 485
            ++K
Sbjct: 1328 VDK 1330



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 35/237 (14%)

Query: 3558 PEFTTTPSDLILSENSSAHFEC--RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            P F++   D  + E      +C  R  PV     R+ W  NG+P+      ++  + G  
Sbjct: 514  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVP----RITWLLNGQPI---QYARSTCEAGVA 566

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I      D G YTC A N  G+  VSC   V              H K  +   + L
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQ--VSCSAWVT------------VHEKKSSRKSEYL 612

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
                     + +   KP  P F   + D + V +G  V    +V   G+P   + W HNG
Sbjct: 613  ---------LPVAPSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 660

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
                     H        +L I  ++  D G YTC A N  G   T A +T     D
Sbjct: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 4/154 (2%)

Query: 1251 TVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            T  AV  +G   + A++  +  R        +    E+++  ED ++   +   +     
Sbjct: 1748 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1807

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD-YV 1368
             P FS+ + ++E VEG+    +C+++   D    V WF + + I+    F+  Y+ D   
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNC 1865

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L +  V  +D   YTC+A N LGEA  +  L V
Sbjct: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 60/244 (24%), Positives = 100/244 (40%), Gaps = 16/244 (6%)

Query: 2226 QGHSTRIEVE---EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
            +GH+   + E   E + + P F  +L+   HV EGK    +CQV    DP   I +  NG
Sbjct: 1079 RGHAGTTDNEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSS--DPPATIIWTLNG 1135

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV----TAKG 2338
            K L++     ++ +    S+ I+  +PED G Y   A N  G    +  +TV     ++ 
Sbjct: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195

Query: 2339 SIISE--SQRPE-GLEKIRELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTA 2394
            +   E  S+RP+  L  +   ES    K+   P+ P     P           ++ G++ 
Sbjct: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255

Query: 2395 HFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
                ++   G   +   W +  K I++S  +   +      +TI   R E  G Y     
Sbjct: 1256 ELFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1313

Query: 2455 NLLG 2458
            N LG
Sbjct: 1314 NKLG 1317



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 3/134 (2%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + +  + +G+     + E   S+    PPK A K     ++EG   +F  +++G P+P+V
Sbjct: 133 QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-- 355
           TW K    L  S +  +   +    L +    + D G YT L  N +G    S  L++  
Sbjct: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252

Query: 356 -ESPTESYVQDQRS 368
            +S   S+V++ ++
Sbjct: 253 LDSANRSFVRETKA 266



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 61/232 (26%), Positives = 91/232 (39%), Gaps = 28/232 (12%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F+  +KD   V EG      C V   G P  RI W  NG+P        +  + G   
Sbjct: 514  PSFSSVLKD-CAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPI---QYARSTCEAGVAE 567

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L I      D G YTC A N  G  + +A +T   K+            S  K + L   
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK------------SSRKSEYL--- 612

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
             +  AP +     T P F+  +    ++  +G +    V+   +P   + W  NG  +  
Sbjct: 613  -LPVAPSK----PTAPIFLQGLSD--LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
               +         SL I  V+ ED+G Y C A N  GE  T+A ++ ++  D
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 4/100 (4%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GY 966
            KP F   I+D + + EG  A F+ ++E   D    V W KD + +  S      ++  G 
Sbjct: 1808 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
             +L I  V   D   YTC+A N++G+AT +A L + T ++
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 55/224 (24%), Positives = 87/224 (38%), Gaps = 12/224 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG  +  +C V  S DP   I W  N K L +      + + S  S+ I
Sbjct: 1100 FKQKLQDVHVAEGKKLLLQCQV--SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQ-----GKAGLEAVEQA 2890
                 ED G+Y C A N  G A  S  +    D     +T+ P+      K+ L  V   
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQV-TVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216

Query: 2891 E-EARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949
            E +A + K   P  P      P+ II    + ++  G+ + L G+V       +   W  
Sbjct: 1217 ESDATVKKKPAPKTPPKAAMPPQ-IIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMK 1273

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
              K +++    K+ +      L ++   +   G YT    NK G
Sbjct: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 4/124 (3%)

Query: 2613 PESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            P + E+++ +E       E   +      P F+  ++  + +VEG     + ++E   DP
Sbjct: 1780 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1838

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
              ++ WFK+  ++      +  +D  G  +L I+ +  DD   YTCKA N LGEA  TA 
Sbjct: 1839 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1896

Query: 2732 IKIE 2735
            + +E
Sbjct: 1897 LIVE 1900



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 5/101 (4%)

Query: 3687 IEDEKPN-PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
            + +EKP+  P F+  I+D ++V EG    FDC++E   DP   + WF + +         
Sbjct: 1800 VAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQ 1856

Query: 3746 -TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               ++ G  +L I  +   D  +YTC+A N  G AT TA++
Sbjct: 1857 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 4/120 (3%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            EKL++ ED      +   EE+    P F+  + ++E + EG  A F+ ++    DP  +V
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV-EGSAARFDCKIEGYPDP--EV 1840

Query: 3455 EWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             W+ + +S++    F+  + + G   L IS    +D  +Y C+A N+ GEA  TA + V+
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 55/226 (24%), Positives = 90/226 (39%), Gaps = 14/226 (6%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F  +L     ++EG+    +C++    DP   + W  NGK L++      S +    
Sbjct: 1097 APAFKQKLQD-VHVAEGKKLLLQCQVSS--DPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-------QSKESIIRDSQHESALEKI 1955
            ++ I     ED G Y C A N+ GQA  S ++ V        +K   ++  + +S+L  +
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213

Query: 1956 QYLEDDSRYKR--AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW 2013
               E D+  K+  A +        PQ  +  ++ +V  G  V L   +T     T    W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT--CTW 1271

Query: 2014 YCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
                + +Q+    K         L IL A  E  G Y     N +G
Sbjct: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 1/87 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYE 4785
            +RD+ V EG  A+F  +I     P + W ++   I E+  FQ+ + E  N  L+I +   
Sbjct: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +D   +TC+A  + G+   +A+L+V++
Sbjct: 1875 DDDAKYTCKAVNSLGEATCTAELIVET 1901



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 52/251 (20%), Positives = 93/251 (37%), Gaps = 10/251 (3%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E   E     P F + LQD+  + EG+    + Q++  SDP   + W  +G+ +  +  I
Sbjct: 1088 EKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFI 1144

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV----AARSTVTADLGIP 875
                     S++I     ED G Y   A N  G+A  +  + V    A+ +T   ++   
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935
              +  +                     P++   P+     +DQ  ++ G       ++  
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ-KVRAGESVELFGKVT- 1262

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             G   +   W+K  + ++ S  +    +     LTI +      G YT    N +G    
Sbjct: 1263 -GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQA 1321

Query: 996  SANLTIVTKKD 1006
              NLT+V K D
Sbjct: 1322 QVNLTVVDKPD 1332



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 5/108 (4%)

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            E  +++ +  +    +E+P V   P F   I+   V E    RF+C++E   DP+  + W
Sbjct: 1787 ESEEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1842

Query: 3866 YRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            +++ + +     ++  YD  G  SL I  V  +D  +Y C+AVN  GE
Sbjct: 1843 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 58/258 (22%), Positives = 90/258 (34%), Gaps = 10/258 (3%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G++GT D        G  P F     D+ ++E      +C++   +D    + W  NGK 
Sbjct: 1080 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKT 1137

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI--IL 3657
            L T   +    +     + I      D GLY C A N  G+A  SC++ V          
Sbjct: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1197

Query: 3658 EPQLPSHF-KSGTESIQKLEE--TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVH 3714
             P++ S   KS    +   E   T+ K+       +   PP+  ++  ++  V  G  V 
Sbjct: 1198 APEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI-IQFPEDQKVRAGESVE 1256

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
               +V   G   +   W    +       +   N      L I        G YT    N
Sbjct: 1257 LFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVEN 1314

Query: 3775 KWGSATTTAKITCSAKRD 3792
            K GS      +T   K D
Sbjct: 1315 KLGSRQAQVNLTVVDKPD 1332



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 32/232 (13%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F + ++D   ++EGQ    +  +     P  ++ W  NG+ + +    R+  + G+  
Sbjct: 514  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401
            L I     E+ G Y C+A N LG+ S  A +    K++      L               
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL--------------- 612

Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461
                      V   K  AP+F   LS+++ + +G       +++    P  +V W  NG 
Sbjct: 613  --------LPVAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVSGNPPP--EVIWLHNGN 661

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             ++    F          L I   +PED+G Y C A+N+ GE  T A + VQ
Sbjct: 662  EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + E+R E   +  AP F +  QD  V EGK     C+V+  P   + W +N + ++    
Sbjct: 1086 DNEKRSE--SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-K 1142

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE---KEQVVAPKFV 494
              IL  E    ++ I      D G+  CVA+N +G+    C++ V +    E   AP+  
Sbjct: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202

Query: 495  ER 496
             R
Sbjct: 1203 SR 1204



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 57/243 (23%), Positives = 98/243 (40%), Gaps = 19/243 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L+  + + EG+    + +V   SD   T+ W  NGK + +   I    +    +
Sbjct: 1098 PAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            + I     ED G+Y  VA+N AG+A+ S  +TV+   + + +   +    K+R  + S  
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT---KAPEMKSRRPKSS-- 1209

Query: 1163 VEPMYQIEEIS--KSKPVFVQP--LSNPPPV---SEGKNIHLECRLEPMGDPT----MRV 1211
            + P+   E  +  K KP    P   + PP +    E + +     +E  G  T    +  
Sbjct: 1210 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1269

Query: 1212 EWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             W    + +      K         L I+ A     G YT+   N LGS      + V++
Sbjct: 1270 TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329

Query: 1272 RSD 1274
            + D
Sbjct: 1330 KPD 1332



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 7/137 (5%)

Query: 2201 VAGHRNIILDTQHPNGLEKIRQLE--AQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            ++G ++       P   EK+   E  +Q     +  E+P + P  + ++      V EG 
Sbjct: 1767 LSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP--YFSKTIRDLEVVEGS 1824

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSV 2317
             A F+C++E   DP   + ++ + ++++ +  F I +D  G  SL I     +D  +Y+ 
Sbjct: 1825 AARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882

Query: 2318 KAINALGHCTSAISMTV 2334
            KA+N+LG  T    + V
Sbjct: 1883 KAVNSLGEATCTAELIV 1899



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 3/131 (2%)

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
            E+++  ED S+     + +E     P  + +++++E+ EG  A F+ ++    D   +V 
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVV 1841

Query: 1613 WYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
            W+ +++ ++    F  + +  G  +L I     +D   YTC+A+N+LGEA  +   IV +
Sbjct: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1901

Query: 1672 KKSIYLESQHE 1682
             +    E + E
Sbjct: 1902 MEEGEGEGEEE 1912



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           P +P+ PIF Q   + +   G       ++ GNP P V W      + E   +   + ++
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQR 674

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
               SL I+++ P D G YTC A N  GE
Sbjct: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/231 (24%), Positives = 89/231 (38%), Gaps = 28/231 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P F+ VL   + + EGQ    +  V   G P  R  W +NG  ++     R+T + G   
Sbjct: 514  PSFSSVLKDCAVI-EGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L I   +  D G Y C A N  G                        +W  +  K+++  
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCS-------------------AWVTVHEKKSSRK 608

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                + V      APIF   L    K+++G  V +  QV     P  ++ W  NG  +  
Sbjct: 609  SEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQVTMTVQVSGNPPP--EVIWLHNGNEIQE 665

Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
                         +L I  +  +D+G YTC+A N  GE  + A + +++ H
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 52/242 (21%), Positives = 89/242 (36%), Gaps = 12/242 (4%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            E +G AP F   L ++ ++ EG+    + +++   DP   + W  NGK+LK  ++F    
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT-TKFIILS 1147

Query: 3474 DFGFVI-LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ---GKRNIILESQLPKGME 3529
              G +  + I    PED G Y C A N+ G+A  +  + V       N        +  +
Sbjct: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207

Query: 3530 GTIDKIAALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
             ++  +   E  +       P+   ++  PP+    P D  +    S     ++      
Sbjct: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQ 1265

Query: 3588 SMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
             +   W    K +     +K  N      L I    Q   G YT    N+ G       L
Sbjct: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325

Query: 3648 QV 3649
             V
Sbjct: 1326 TV 1327



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F+  L  +  M+G ++    ++   G+P  ++ WL NG  I+ S  F    R    SL
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +  +  +D+G YTC A ++ G   T+AVL V
Sbjct: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIK 4749
            GD K VA +   + +++              PA + P R++ + EG  A+F+ ++    +
Sbjct: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            P + W R G  I     F ++  G      L+I   +EED G +TC AT  +G  + + +
Sbjct: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 4808 LVVK 4811
            L V+
Sbjct: 121  LTVE 124



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 57/237 (24%), Positives = 91/237 (38%), Gaps = 33/237 (13%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F   L+D   + EG++  F  Q +    P  R+ W  +G+PI  +    S    G   
Sbjct: 514  PSFSSVLKDCAVI-EGQD--FVLQCSVRGTPVPRITWLLNGQPIQYAR---STCEAGVAE 567

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L+I     ED G+YT  A N LG+   +A + V  + +         +  Y+        
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-------SRKSEYLLPVA---- 616

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                         P     P F   + D + + +G       ++   G+    V WL +G
Sbjct: 617  -------------PSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 660

Query: 950  RPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
              ++ S            +L I+ V   D G YTC A+N+ G+  T A LT+    D
Sbjct: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 630  EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            E++ +  P F   ++ +  +EG    F+ +IE   DP  ++ W K+ QSI  S  F   +
Sbjct: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDY 1859

Query: 690  -RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
               G  SL +  +   D  +YTC+AV++ G A   A L V
Sbjct: 1860 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 27/226 (11%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F   LK    +EG     +  +   G P  +I WL NGQ I+ +    S    G   L
Sbjct: 514 PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 568

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
            +     +D G YTC A +A G     A + V  + +  +                 S+Y
Sbjct: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK-----------------SEY 611

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
               +  + T+  P F++ L DL ++ +G       Q++   +P   V W  +G  I  S
Sbjct: 612 LLPVAPSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 666

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                       SL I  +  ED G+YT  A N  GE  + A + V
Sbjct: 667 EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 58/229 (25%), Positives = 81/229 (35%), Gaps = 27/229 (11%)

Query: 3988 METTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYL 4047
            +E   F  Q +  G P  ++ W  NG+P+ +  R T   + G   ++     PED G Y 
Sbjct: 526  IEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RST--CEAGVAELHIQDALPEDHGTYT 582

Query: 4048 CRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKA 4107
            C A N  G     A +                H K  +  R+ E    V P      SK 
Sbjct: 583  CLAENALGQVSCSAWVTV--------------HEK--KSSRKSEYLLPVAP------SKP 620

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH- 4166
              P     L D + V +G       +V+G+P P V+WL NGN I     +     G  H 
Sbjct: 621  TAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679

Query: 4167 FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
              I +    DTG                  L V   HD  +    + PR
Sbjct: 680  LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 19/282 (6%)

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQ 1979
            + +  +G A     L   SKE + +D +++   ++      D+  +   Q  +     P 
Sbjct: 1045 ETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTA-----PA 1099

Query: 1980 FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDI 2039
            F + +++  V EG  + L+  ++  +DP   + W  NG+ ++       + +    ++ I
Sbjct: 1100 FKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 2040 LYAYAEDTGTYMCKATNAVGEAVTTSSVKVD---AKSGLYLDTLDEQRLKKI------QE 2090
              A  ED G Y C A N  G+A  +  V VD   A        +  +R K         E
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217

Query: 2091 LEKYERPKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
             +   + KP  +  P    P  +      + ++ G+      +V       +T  W    
Sbjct: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMKFR 1275

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            ++I+     +  +      L IL    E  G Y     NKLG
Sbjct: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F   L+    + EG+ + L+ QV   +DP   I W  NG TL T   +  + +  L 
Sbjct: 1097 APAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            ++SI     +D G+Y C A N  G+A  +  + ++D
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 11/154 (7%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT-TDSGTYSCRATNKWGQAEISVK-LEC 3140
            +W   G  + A  R+ ++     ++  + G K+ T S T    A     + ++S   LE 
Sbjct: 1744 KWQKTGNAVRAIGRLSSM----AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1799

Query: 3141 VDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199
            V + K   KP F+  I+++E + +G +A F+C +    DP+  + W+ + Q +R S   +
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQ 1856

Query: 3200 -TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                + G   L I+     D  +Y C+A N  GE
Sbjct: 1857 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP F+  L +   + EG++   +  +  T  P  ++ W  NG+ ++     R+ C+ G  
Sbjct: 513  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 566

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQL----PKGMEGTI-- 3532
             L I    PED G Y C A N  G+   +A + V  K++      L    P      I  
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECR 3580
              ++ L+   G+  T+T +     PPE     +   + E+   HFE R
Sbjct: 627  QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 3/116 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMHDFGYVA 1769
            P F    +   V ENQ   F   +   G PK  V W   G P+      +    + G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHY 471

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            L +      DSGTY+C A N  G+   S TL V+  A +++     S L+    +E
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 16/245 (6%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            +S+G  P F   +Q++  + +G+    +C V    DP   I W  NG+ ++ +  I    
Sbjct: 1092 ESQGTAPAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1148

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATIN----CYGKGGVYLESLQP-D 3255
            +     + I      D G Y C A N  G  E   + T++            ++S +P  
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208

Query: 3256 SLAKIRELESLQGAQQQ-TPSTP--SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDP 3312
            SL  +   ES    +++  P TP  +A PP+ I Q  +  K+  G+S     ++      
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQII-QFPEDQKVRAGESVELFGKVTGTQ-- 1265

Query: 3313 DLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +   W    K++      +  +      L IL   +E+ G Y  +  NKLG    + NL
Sbjct: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325

Query: 3373 KCTSK 3377
                K
Sbjct: 1326 TVVDK 1330



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 42/151 (27%), Positives = 69/151 (45%), Gaps = 9/151 (5%)

Query: 1127 AQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNP 1186
            A +S     ++ +   TS ++    E    + ++ F+E +   EE    KP F + + + 
Sbjct: 1762 AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQA-FLEAV--AEEKPHVKPYFSKTIRDL 1818

Query: 1187 PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFVALDIIHATSA 1245
              V EG     +C++E   DP   V WF + +S+     F+  YD  G  +L I      
Sbjct: 1819 EVV-EGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1875

Query: 1246 DTGEYTVRAVNHLGSAHTSA--IVRVIERSD 1274
            D  +YT +AVN LG A  +A  IV  +E  +
Sbjct: 1876 DDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 4078 PKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGH 4137
            P    + EK+   E   Q   E V EE K    P F      + V EG  ARF C++ G+
Sbjct: 1777 PTSPLNAEKLESEEDVSQAFLEAVAEE-KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1835

Query: 4138 PKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P P V+W  +  +I     +++ YD
Sbjct: 1836 PDPEVVWFKDDQSIRESRHFQIDYD 1860



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT--YDGMYHFD 4168
            P F+  P  + ++EG  A+F  RV G+P+P+V W  NG  I +G R+ L     G +   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4169 IPKTRQYDTGK 4179
            I    + D GK
Sbjct: 93   IHAVHEEDRGK 103



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 37/239 (15%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            ++   P F + +K   V E +    +C V  +  P  RI W  NG+ +      R+  + 
Sbjct: 509  VMEVAPSFSSVLKDCAVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 563

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            G   L I     ED G Y C A N  G+      +SC     +       +  ++SE L 
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQ------VSCSAWVTV----HEKKSSRKSEYL- 612

Query: 3945 QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPN 4004
             +     K T+ ++L                    Q  + L  M+ ++    +   G+P 
Sbjct: 613  -LPVAPSKPTAPIFL--------------------QGLSDLKVMDGSQVTMTVQVSGNPP 651

Query: 4005 MKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
             +V W  NG  +     F         ++    V+PED+G Y C A N  G   T+AV+
Sbjct: 652  PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 40/129 (31%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 44  FTRQMTTQVESS--GDRQPITA--GRP---GEPSPPIFEQIFKNARFAQGGNAKFEGKLR 96
           F +Q+   V S   GDR   +A   RP   GE  PP F          +G   +F  K+ 
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE-CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P V+W +   PL    + S+  +E+ G   L I  +   D G YTC   N  G+A 
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSV--SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243

Query: 157 CSVYIQPEG 165
            S  +  +G
Sbjct: 244 MSAELSIQG 252



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 54/241 (22%), Positives = 84/241 (34%), Gaps = 15/241 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  +++D + V EG  +   C+V    DP   I W  NG+   T   +    +    +
Sbjct: 1098 PAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER- 3813
            + I+     D G Y C A N  G A  + ++T          ++ P+  S      L   
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD-DAPASENTKAPEMKSRRPKSSLPPV 1213

Query: 3814 -GRISDA-------PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
             G  SDA       PK  P  + PP+ I   +   V   E V    +V   +   +   W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQ--PITCTW 1271

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             +  K +      +         L IL    E  G Y     N  G    +  ++    P
Sbjct: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331

Query: 3926 D 3926
            D
Sbjct: 1332 D 1332



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD-FSYVSLD 2834
            F   + ++   EG    F+C +E   DP  ++ WF +++ +     ++  +D     SL 
Sbjct: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I+    +D   YTCKA NS G AT +  L
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/86 (25%), Positives = 41/86 (47%)

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            + Q  AP F ++   ++V EG+ ++L  +    P   I W  +G  +     + +  +G 
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
              ++ I +A   D   Y+C A+N AG
Sbjct: 1152 LCSVSIEKALPEDRGLYKCVAKNDAG 1177



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592
            +K+ + E  S        E +    P F+ T  DL + E S+A F+C++    D    V 
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VV 1841

Query: 3593 WFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            WF + + +      +   ++ G   L I  V   D   YTCKA N  GEAT + +L V+
Sbjct: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 56/240 (23%), Positives = 92/240 (38%), Gaps = 17/240 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP     L++V + EG++   + ++   SD    + W  N K LK+      +      +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV------HSKKSIYLESQH-EGALPRLN 1689
            + I   LPED G Y C A N  G+A  S    V       + K+  ++S+  + +LP + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ--AAHFEARLI--PVGDPKLRVE 1745
              E  +  ++  A        P   MP + I+  E+Q   A     L     G   +   
Sbjct: 1215 GTESDATVKKKPAP----KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W++    I+ S  +   +      L +     E  G YT    N+LG       L V  K
Sbjct: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 3/110 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS-RVKTINDFGFVI 3616
            P+F + P    + EN +  F C +  +      V WF  G P+      ++   + G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGI--PKPEVAWFLEGTPVRRQEGSIEVYENAGSHY 471

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            L +     RD+G Y+C A+N  G+ + S  LQV+    + + P   S  K
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLK 521



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            E  G  P F   L  + ++ EG +   +C+V   +DP  TI W  NG+ ++       + 
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1148

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +    ++ I     ED G Y C A N  G+A  +C + V
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 1/100 (1%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNH 320
            P   P  ++  R+ ++ EG+ A+F  ++ G P P V WFK+ Q +  S   +I      +
Sbjct: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             +L + +    D   YT  A N  G    +  L VE+  E
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD-FGYVA 2036
            P+F    ++ EV E   V     ++ +  P   V W+  G PV++       Y+  G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYENAGSHY 471

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            L +L A   D+GTY C A+NA G+   + +++V+
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVE 505



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 4/84 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD-FGYV 4031
            P+F ++ QSQ  + E +T KF C+++  G P  +V WF  G P+  +     +Y+  G  
Sbjct: 414  PKFESKPQSQ-EVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYENAGSH 470

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYG 4055
             +        DSG Y C A+N  G
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQG 494



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLTYDGMYHFD 4168
            P F S P +  V+E +  +F C V+G PKP V W L G  +    GS       G ++  
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLC 473

Query: 4169 IPKTRQYDTG 4178
            + K R  D+G
Sbjct: 474  LLKARTRDSG 483



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 4/104 (3%)

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH-R 2157
            P+E ++    P F +   S E +KE     F C V  I  P +   WF  G  +R     
Sbjct: 404  PMEGQRDSAFPKFESKPQSQE-VKENQTVKFRCEVSGIPKPEVA--WFLEGTPVRRQEGS 460

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 + G   L +L     DSGTY C A+N  G+   + TL+V
Sbjct: 461  IEVYENAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 2/111 (1%)

Query: 470  KSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            +S E   Q  L  + +E+  V P F +    L V EG     + +  G P P + W KD 
Sbjct: 1787 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846

Query: 529  VPIIPNPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              I  +   +I + + G  +L I      D A Y C A N  G     A L
Sbjct: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            P E    S  PKF ++ +S  V+E++ V+F C V     PK  + W+  G  +       
Sbjct: 404  PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEV--SGIPKPEVAWFLEGTPVRRQEGSI 461

Query: 3880 TVYD-MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
             VY+  G   L +L     DSG Y C A N  G+     T+  ++L
Sbjct: 462  EVYENAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERL 507



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++ ++ EG+     C++    DP   + W  N K ++ +  I  + +    S
Sbjct: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            ++I     ED G+Y C A N  G+
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQ 1178



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNKYS 119
           +T   P + + P F    ++   + G +      + G+P P V W R  KA   +   + 
Sbjct: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769

Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSV 159
           +  NE     +L++K++ P   G+Y    +N+ GE  C V
Sbjct: 770 VLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQV 807



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 43/192 (22%), Positives = 68/192 (35%), Gaps = 10/192 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            T+++     +   P F  ++Q    + E +    +CQ++   DP   + W  NGK L   
Sbjct: 1085 TDNEKRSESQGTAPAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTT 1141

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV------Y 4073
                   +    +++     PED G Y C A N  G  E    +     P          
Sbjct: 1142 KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEM 1201

Query: 4074 DSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCR 4133
             S+ PK         E +A+ +  P       KA  PP  +  P+   V  GE      +
Sbjct: 1202 KSRRPKSSLPPVLGTESDATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVRAGESVELFGK 1260

Query: 4134 VTGHPKPRVMWL 4145
            VTG       W+
Sbjct: 1261 VTGTQPITCTWM 1272



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+Q  ++   A+G     + ++  +P   + WT     L +  K+ +  +++    S+
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFII-LSQEGSLCSV 1155

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             I++  P D G Y C A+N  G+A CS  +
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQV 1185



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERD 2980
            ++VEG     + ++E   DP+  + W+ + + + +   F++  D  G  +L + DV   D
Sbjct: 1819 EVVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1876

Query: 2981 SGIYTCKAYNKRGEA 2995
               YTCKA N  GEA
Sbjct: 1877 DAKYTCKAVNSLGEA 1891



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE-FDYVA 1369
            P+F     + E  E   V   C +   G     V WF  G P++        YE      
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHY 471

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L LL     DSG Y+C A+N  G+   S  L+V
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            +D  K      T P F  +++   V E + +  +C+V    DP   I W  NGK L +  
Sbjct: 1085 TDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTK 1142

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
                  +    S+ I     ED G Y C A ND G+
Sbjct: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 4/94 (4%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYV 967
            P+F++  + Q  +KE     F  R E  G     V W  +G PV      I  + N G  
Sbjct: 414  PKFESKPQSQ-EVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSH 470

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L +      D+G Y+C A NA GQ + S  L +
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIV--NGSRYKL 4159
            V+E      P F+S P +VT   G+     C + G P P V WL +G  +    G    L
Sbjct: 712  VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771

Query: 4160 TYDGMYHFDIPKTRQYDTGKIEVI 4183
              + ++   + K + +  G+ E++
Sbjct: 772  QNEDVFTLVLKKVQPWHAGQYEIL 795



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/92 (22%), Positives = 41/92 (44%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F +K+Q   V E ++   + +   +P   I W      +K +    +    +   + I
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
             +   ED  ++  VA+N  G A+CS  + V++
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 3013 TQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASL 3072
            T  P      EK+++ ED  +       ++     P F+   +D+ ++ EG  A ++  +
Sbjct: 1774 TGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKI 1832

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
                D  +V  WF + ++I  S   +  Y   G   L I      D   Y+C+A N  G+
Sbjct: 1833 EGYPDPEVV--WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890

Query: 3132 AEISVKL--ECVDKSKGQ 3147
            A  + +L  E +++ +G+
Sbjct: 1891 ATCTAELIVETMEEGEGE 1908



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 14/127 (11%)

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPK----FITQIQDVTKLVEGQSAHFEARLVPV 3309
            P S     +LES +   Q      + E P     F   I+D+ ++VEG +A F+ ++   
Sbjct: 1777 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGY 1835

Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHD----FGIVILDILYCYEENSGEYECVATNKLGR 3365
             DP+  V WF + + +     ++  +D      ++I D+  C ++++ +Y C A N LG 
Sbjct: 1836 PDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV--CGDDDA-KYTCKAVNSLGE 1890

Query: 3366 DSTKANL 3372
             +  A L
Sbjct: 1891 ATCTAEL 1897



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GF 2565
            KP F++ +    E+ EG  A ++ ++    DP +   W+ +   ++    F+  +D  G 
Sbjct: 1808 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEV--VWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I+ V  +D   Y CKA+N  G
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLG 1889



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQSGHRYRTSNDFGFAALDILTVYGED 1913
            ++ E Q+  + C +   P P   V W+  G  V +         + G   L +L     D
Sbjct: 424  EVKENQTVKFRCEVSGIPKPE--VAWFLEGTPVRRQEGSIEVYENAGSHYLCLLKARTRD 481

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQ 1937
            SG Y+C A N  GQ   S  L V+
Sbjct: 482  SGTYSCTASNAQGQVSCSWTLQVE 505



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 3/63 (4%)

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            ++  SW +  E++     A   P F S+     V EG+     C V G P PR+ WLLNG
Sbjct: 495  QVSCSWTLQVERLAVMEVA---PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551

Query: 4149 NTI 4151
              I
Sbjct: 552  QPI 554



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 2232 IEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL-QSAA 2289
            + V+EP   + P F+++ R  T    G++    C +    DP   + +  +GKAL +   
Sbjct: 710  LTVQEPHDGTQPWFISKPRSVTASL-GQSVLISCAI--AGDPFPTVHWLRDGKALCKDTG 766

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS-MTVTAKGSIISESQRPE 2348
             F +  +    +L ++   P  AG+Y +   N +G C+  +S M   +    +   + P 
Sbjct: 767  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 826

Query: 2349 GLEKI 2353
              E +
Sbjct: 827  SCEDL 831



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 5/109 (4%)

Query: 628 GEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTS 687
           G+ D  +P  +F    +S    E   + F  R E  G P  ++ W   G  +        
Sbjct: 407 GQRDSAFP--KFESKPQSQEVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462

Query: 688 IFR-FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
           ++   G   L +L    +DSG Y+C A +A G       L V   A +E
Sbjct: 463 VYENAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME 511



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 13/120 (10%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL--PSGHRYR 3879
            +EP   T P FI++ +S T    + V   C +    DP   + W R+GK L   +GH + 
Sbjct: 713  QEPHDGTQPWFISKPRSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGH-FE 769

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
             + +    +L +  V    +G+Y     N  GE        C     ++LQN   R + R
Sbjct: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--------CSCQVSLMLQNSSARALPR 821



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 33/88 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P+ ++      VR GE V L  +  GT     TW K    I  +  +++      S L I
Sbjct: 1238 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A+      Y    +N  GS   +  L
Sbjct: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNL 1325



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 1738 GDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            GDP   V WLR+G  + + +     + +     L +K V P  +G Y     N +GE   
Sbjct: 746  GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 805

Query: 1797 SSTLFVQSKASLQLESQHESA 1817
              +L +Q+ ++  L    E A
Sbjct: 806  QVSLMLQNSSARALPRGREPA 826



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
            +E+RSE    +   P F Q L     + EG+    + +V    DP     W +NG  LK 
Sbjct: 1087 NEKRSES---QGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT 1140

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                  + +    ++ I   +  D GLY C A N AG
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAG 1177


>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
            kinase protein.
          Length = 1914

 Score =  167 bits (407), Expect = 7e-40
 Identities = 116/431 (26%), Positives = 185/431 (42%), Gaps = 13/431 (3%)

Query: 4389 EIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN 4448
            ++  KA  +   +EG  + S  P F  K Q   V E++  +F  E  G P P + W+ E 
Sbjct: 393  DVVSKAANRRIPMEGQ-RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEG 451

Query: 4449 FPIKNSP-DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
             P++      +++  +    L + +    DS  ++  A N  G   CS  L VE      
Sbjct: 452  TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME 511

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567
                V PSF+   ++  V  GQ   L   V GT    + WL NG+ +Q   R+    E G
Sbjct: 512  ----VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTC--EAG 564

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK---PQTKAANAPPE 4624
               L I +A P+D G Y C+A N+ G+  C A   V    +  K +   P   +    P 
Sbjct: 565  VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
             ++ L D  V +G  +  + ++ G P P V W      I+ S+ F   +   +++L I E
Sbjct: 625  FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
             FPED G Y C A+NSAG V   A L V +P        ++  R +    GQ       I
Sbjct: 685  VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744

Query: 4745 TSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                 PT+ WLR+G AL  +T  F+++   +   L++        G +        G+  
Sbjct: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804

Query: 4804 TSAKLVVKSKT 4814
                L++++ +
Sbjct: 805  CQVSLMLQNSS 815



 Score =  109 bits (262), Expect = 2e-22
 Identities = 80/334 (23%), Positives = 136/334 (40%), Gaps = 19/334 (5%)

Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
           G+     + +++R       P  +   ++  + EG D   Q  + G P PR+TW  NGQ 
Sbjct: 494 GQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553

Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
           +  +             L +++    D G YT LAEN  G +  S ++ V     S    
Sbjct: 554 IQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS---- 606

Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           ++S+Y+                K  AP F++   D  V +G       +V+G P PEV W
Sbjct: 607 RKSEYLLPVAP----------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             N  +I++  +          H+L I  V   D+G  TC A N +GE   Q  L V E 
Sbjct: 657 LHNGNEIQESEDFHF-EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715

Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGG 544
                P F+ +  ++    G+ V+++    G P P + W +DG  +  +     +  +  
Sbjct: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775

Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             TL + + +   A  Y+   +N  G  + +  L
Sbjct: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809



 Score =  107 bits (258), Expect = 7e-22
 Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 14/235 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-G 3476
            +AP F +P  N+  ++EG  A FE R+    +P  +V W+ NG+ + +G RF   C   G
Sbjct: 31   EAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 3477 FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIA 3536
               L I   + ED G+Y C A N  G    T  + V+G        QL + +   + K  
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPV---VSKTL 140

Query: 3537 ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
                 +  V+T  P      PP+F T    +++ E     F C++        +V W   
Sbjct: 141  GDRFSASAVET-RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
              PL   +RV      G  +LEI GV Q D G+YTC   N  G+A++S +L ++G
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score =  105 bits (251), Expect = 5e-21
 Identities = 88/328 (26%), Positives = 132/328 (40%), Gaps = 46/328 (14%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEIITTHNHTTLR 324
           PK   KP++ +++E    +F+ ++SG P+P V WF  G  +       E+        L 
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +   +  DSG Y+  A N  G +  S  L VE                         R+ 
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVE-------------------------RLA 508

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
           + E  +AP F  V +D  V EG+     C V G P P +TW +N + I+  Y       E
Sbjct: 509 VME--VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTC--E 562

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE--------------QVVA 490
           +G   L I +    D G  TC+A N  G+ +    + V EK+              +  A
Sbjct: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P F++  S L V +G  V +  +  G P P + W  +G  I  + +      G   +L I
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682

Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARL 578
                 D   Y C A N AG   T+A L
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score =  102 bits (244), Expect = 4e-20
 Identities = 76/245 (31%), Positives = 112/245 (45%), Gaps = 10/245 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDF 1765
            +T+AP F +P +++ + E   A FE R+   G P+ +V W RNG PI +  R L      
Sbjct: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G  +L +  V+ ED G YTC A N  G    +  L V+   + QL     S  + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS--KTLGDRF 144

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             +S  + R  +       P+F T+L G   + EGQ   + C+I   P P  +V W     
Sbjct: 145  SASAVETRPSIWGEC--PPKFATKL-GRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNV 199

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
             LQ   R   S   G   L+I  V  +D G YTC  +N  G+A  S  L++Q  +S  R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 1946 SQHES 1950
               E+
Sbjct: 260  FVRET 264



 Score =  101 bits (242), Expect = 6e-20
 Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 8/219 (3%)

Query: 4404 PVKPSKP--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            PV PSKP  PIF + +   +V +  Q    V+  G P P + W      I+ S DF    
Sbjct: 614  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
              T+  L I++VF ED+  +   A N  G  +  A L V+E    G      P F    +
Sbjct: 674  RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH-DG----TQPWFISKPR 728

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQD 4580
            +V  + GQ V +   + G     V+WL++GK +  D  + ++L+ +  +TL++ +  P  
Sbjct: 729  SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +G+YE +  N  GE  C    ++   + +  P+ +  A+
Sbjct: 789  AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPAS 827



 Score =  100 bits (240), Expect = 1e-19
 Identities = 68/246 (27%), Positives = 114/246 (46%), Gaps = 5/246 (2%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           +   ++ ++ + +      S+     P     PRN  ++EGA A+F+ ++ G P P+VTW
Sbjct: 7   VASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTW 66

Query: 300 FKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-S 357
            +NGQ + +  +  +      T +L +    + D G YT  A N +G    +  L VE S
Sbjct: 67  HRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126

Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
             +   Q   S+ + D       E          P+F        V EG+M RF C++TG
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNE-SGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
           RP P+VTW   +  ++   + ++ V+E +G   L I  V   D GV TC+  N SG+ + 
Sbjct: 187 RPQPQVTWLKGNVPLQP--SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244

Query: 477 QCRLNV 482
              L++
Sbjct: 245 SAELSI 250



 Score =  100 bits (240), Expect = 1e-19
 Identities = 107/361 (29%), Positives = 152/361 (42%), Gaps = 62/361 (17%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH-DFGYV 1502
            P+F ++P+S E V E Q V F C++  +     +V WF  G PV        ++ D G  
Sbjct: 414  PKFESKPQSQE-VKENQTVKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L ++     DSG Y+C A N  G  +VSC  T +              +E++ V+E   
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQG--QVSCSWTLQ--------------VERLAVME--- 511

Query: 1563 KYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKS 1622
                          AP  ++ LK+  + EGQ   F  +         ++ W  N +P++ 
Sbjct: 512  -------------VAPSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQY 556

Query: 1623 GSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHE 1682
                 E    G   L I   LPED GTYTC A NALG+   S    VH KKS     + E
Sbjct: 557  ARSTCEA---GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS---SRKSE 610

Query: 1683 GALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL 1742
              LP        SK             AP+F   + D++V +        ++   G+P  
Sbjct: 611  YLLP-----VAPSK-----------PTAPIFLQGLSDLKVMDGSQVTMTVQV--SGNPPP 652

Query: 1743 RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             V WL NG  I+ S            +L ++ V PED+GTYTC A N  GE  T + L V
Sbjct: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712

Query: 1803 Q 1803
            Q
Sbjct: 713  Q 713



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 19/225 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P+F L  +N+ +  G   + + +V G     V W +NG+ +    R  +     GT++L+
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP---------------QTK 4617
            I   + +D GKY C A N +G  +   E  V     K   +P               +T+
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4618 AA---NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             +     PP+    L   +V EGQ   FSCKI G+P P V W KG+  ++PS    +S  
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
                 L I     +D G Y C+  N +G+ +++A+L +   D A+
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 167/703 (23%), Positives = 277/703 (39%), Gaps = 94/703 (13%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            FI    N+  KEG    FE  V    +P  ++ W  N +P+ SG R+          SL 
Sbjct: 35   FILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I   +EED G YTC+ATN  G+   +  L   G     F  Q  Q        ++   + 
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSAS- 147

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
             A   RPS+   E P P++   +     + EGQ+     ++  +  P  ++ W      L
Sbjct: 148  -AVETRPSIWG-ECP-PKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPL 201

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD----NLI 3010
            +  +R  ++   G   L++  V + D G+YTC   N  G+A  S+ +     D    + +
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261

Query: 3011 ERTQHPKGTEGLE---------KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDIS 3061
              T+        E         K+ +LE + + +    P    G PP             
Sbjct: 262  RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRG-GSPP--WAANSQPQPPR 318

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK-----TT 3116
            E ++   + S   T  Q+ V++   +  T++A+       A G+ VL   G +       
Sbjct: 319  ESKLESCKDS-PRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP 377

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQK----PRFTTHIQNIEGLKDGQSAHFECT 3172
               T+  R      Q  +S         +GQ+    P+F +  Q+ E +K+ Q+  F C 
Sbjct: 378  RPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE-VKENQTVKFRCE 436

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHST-RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            V  +  P+  + W+  G P+R     I+   D G   L +   +  DSG Y C A N  G
Sbjct: 437  VSGIPKPE--VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494

Query: 3232 EDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDV 3291
            +      ++C         +LQ + LA            +  PS        F + ++D 
Sbjct: 495  Q------VSCSW-------TLQVERLA----------VMEVAPS--------FSSVLKDC 523

Query: 3292 TKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEEN 3351
              ++EGQ   F  +      P  ++ W  NG+ + +    R+  + G+  L I     E+
Sbjct: 524  A-VIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPED 577

Query: 3352 SGEYECVATNKLGRDSTKA----NLKCTSKENLILDSQLPRGMEG-----GLEKLQTLED 3402
             G Y C+A N LG+ S  A    + K +S+++  L    P          GL  L+ ++ 
Sbjct: 578  HGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDG 637

Query: 3403 SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLT 3445
            S V    T   +  G  P   + L N   ++E E+ HFE R T
Sbjct: 638  SQV----TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 18/246 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-VKTINDFGFVI 3616
            P F   P +L + E ++A FE R+    +   +V W  NG+P+ +G R +      G   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V++ D G YTC+ATN  G   V+ +L V+G        QL     S T   +   
Sbjct: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSA 146

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
              +  R  I  E     PP+F  ++   + V EG    F C++   G P  ++ W     
Sbjct: 147  SAVETRPSIWGEC----PPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNV 199

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC----SAKRD 3792
            P    +RV      G   L+I  +   D G YTC   N  G A+ +A+++     SA R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 3793 IVLESQ 3798
             V E++
Sbjct: 260  FVRETK 265



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 64/224 (28%), Positives = 96/224 (42%), Gaps = 25/224 (11%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F   +K+  V EG    L+ ++     P  R+ W  NG+P+Q     ++T + G   L
Sbjct: 514  PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 568

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             I  A  ED GTY C A NA+G+   ++ V V  K                +   K E  
Sbjct: 569  HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK----------------KSSRKSEYL 612

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
             P+   +P   P+FL  L+   +LK  D +     V+   +P   + W HNG +I+    
Sbjct: 613  LPVAPSKP-TAPIFLQGLS---DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +         +L I   + ED+GTY C+A N  GE      L V
Sbjct: 669  FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 16/225 (7%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGFIALDIDYIYA 3762
            N+ + EG    F+ RV   G P  ++ W  NG+P  +G R +      G  +L I  ++ 
Sbjct: 41   NLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS-DAPK 3821
             D G+YTC ATN  G+   T ++T           QL Q +  + + +    R S  A +
Sbjct: 99   EDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGD----RFSASAVE 150

Query: 3822 EEPIV--STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              P +    PPKF T++    V+E +  RF C++  +  P  ++ W +    L    R  
Sbjct: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVS 208

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
                 G   L+I  V  +D G Y C  VN  G+    A +S + L
Sbjct: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 18/242 (7%)

Query: 2899 RRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS 2958
            R  S+P TE   P +I+P      + EG     EG+V  +  P+ ++ W+ NG+ +  G 
Sbjct: 23   RVDSMPLTE--APAFILP-PRNLCIKEGATAKFEGRV--RGYPEPQVTWHRNGQPITSGG 77

Query: 2959 RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK 3017
            RF L     G  +L +  V+E D G YTC+A N  G      TV  T + +  ++   P 
Sbjct: 78   RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPV 135

Query: 3018 GTEGLEKIQNLEDSLRKEPGQQPDDDTGR-PPEFTTVFKDIVDISEGQIAHYEASLIPTG 3076
             ++       L D       +      G  PP+F T    +V + EGQ+  +   +  TG
Sbjct: 136  VSK------TLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKI--TG 186

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
                 + W      ++ S R+      GM VLEI G    D G Y+C   N  G+A +S 
Sbjct: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246

Query: 3137 KL 3138
            +L
Sbjct: 247  EL 248



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 70/260 (26%), Positives = 115/260 (44%), Gaps = 36/260 (13%)

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            EKR + +G    P+F    Q+V+V  G+ + L  +V+   P  + W  NGK ++   +  
Sbjct: 1088 EKRSESQG--TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFI 1144

Query: 4562 ILEEDGTYTLLILE-AYPQDSGKYECVAINSAGEARCDAECVV-SLPATKDKPKPQTK-- 4617
            IL ++G+   + +E A P+D G Y+CVA N AG+A C  +  V   PA+++   P+ K  
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204

Query: 4618 ----------------------AANAPP------EIIEPLKDKIVAEGQAIEFSCKIVGK 4649
                                  A   PP      +II+  +D+ V  G+++E   K+ G 
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
               T  W K  K I+ S++ ++  + +   L I  A  E  G Y  +  N  G       
Sbjct: 1265 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1324

Query: 4710 LKVT-QPDQADNLPALTPLR 4728
            L V  +PD     P  + +R
Sbjct: 1325 LTVVDKPDPPAGTPCASDIR 1344



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 62/249 (24%), Positives = 111/249 (44%), Gaps = 12/249 (4%)

Query: 617 HVERARPYIPPGEEDRV--YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLK 674
           H+ +    + P   D +     P FI+P +++   EG    FE R+   G P  ++ W +
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHR 68

Query: 675 NGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
           NGQ I +  RF       G  SL + +++ +D G+YTC A + +G  +    + +T   +
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV--TVELTVEGS 126

Query: 734 IERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQ 793
             +    P   + +      S  + + SI  +    P+F   L  +  ++EG+   F  +
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECP--PKFATKLGRV-VVKEGQMGRFSCK 183

Query: 794 LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           +T    P  +V W K   P+  S+R++     G   L I  +  +D G YT   VN  G+
Sbjct: 184 IT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241

Query: 854 AISTASIRV 862
           A  +A + +
Sbjct: 242 ASMSAELSI 250



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 65/228 (28%), Positives = 99/228 (43%), Gaps = 14/228 (6%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            +T  P F+  P+++  + EG    FE ++    +   +V W +NGQP+T G RF      
Sbjct: 29   LTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGI 85

Query: 1500 -GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI-QV 1557
             G  +L I  +  ED G YTC A N  G  +V+  LT         S   + G   + + 
Sbjct: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG------SFAKQLGQPVVSKT 139

Query: 1558 LEDRSKYHRTDMVDEVTTQAPI-CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            L DR      +    +  + P    T L  V +KEGQ   F  ++        +V W   
Sbjct: 140  LGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            N PL+  +R + +   G   L+I     +D G YTC  +N  G+A  S
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 15/244 (6%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF- 964
            T+ P F  P ++ + IKEG  A FE R+   G    +V W ++G+P+ +  R        
Sbjct: 30   TEAPAFILPPRN-LCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
            G  +L I +V   D G YTC A N  G    +  LT+  +     +   P   + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRF 144

Query: 1025 DASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEWYFN 1082
             AS  +  T   +     P+F   L G   + EGQ   F  ++   PQ  +T    W   
Sbjct: 145  SAS--AVETRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVT----WLKG 197

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
               +  + R+      G   L+I  V  +D GVYT +  N +G+A +SA ++++   S +
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257

Query: 1143 TSSI 1146
             S +
Sbjct: 258  RSFV 261



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 80/317 (25%), Positives = 135/317 (42%), Gaps = 33/317 (10%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA-FGMVVLEILGTKTTD 3117
            ++ E Q   +   +  +G     + WF  G  +        VY   G   L +L  +T D
Sbjct: 424  EVKENQTVKFRCEV--SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            SGTYSC A+N  GQ   S  L+    +  +  P F++ +++   + +GQ    +C+V   
Sbjct: 482  SGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDC-AVIEGQDFVLQCSVRGT 540

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P  +I W  NGQP++++   ++  + G   L I      D G Y C A N  G+    
Sbjct: 541  PVP--RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCS 595

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +  + K      S + + L  +             PS P+A  P F+  + D+ K+++
Sbjct: 596  AWVTVHEK----KSSRKSEYLLPV------------APSKPTA--PIFLQGLSDL-KVMD 636

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV-ILDILYCYEENSGEY 3355
            G       ++    +P  +V W +NG ++     +  F   G    L I   + E++G Y
Sbjct: 637  GSQVTMTVQV--SGNPPPEVIWLHNGNEIQESEDFH-FEQRGTQHSLCIQEVFPEDTGTY 693

Query: 3356 ECVATNKLGRDSTKANL 3372
             C A N  G   T+A L
Sbjct: 694  TCEAWNSAGEVRTQAVL 710



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 39/107 (36%), Positives = 57/107 (53%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            E +   +  + P F K  +D +V EG   RFDC++ G P PEV WF +D+ IR+  + +I
Sbjct: 1798 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1857

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
              +E GN +L+I++V   D    TC A N  GE      L V   E+
Sbjct: 1858 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 11/215 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGI 2714
            EG     E +V    +P  ++ W +NG  +T+G R        G  +L I+++  +D G 
Sbjct: 46   EGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2715 YTCKATNLLGEAVSTASIKIEDRHWL-LGESLHPDSL-DRIGALXXXXXXXXXXXXXXXX 2772
            YTC+ATN  G    T  + +E      LG+ +   +L DR  A                 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA----SAVETRPSIWGEC 159

Query: 2773 XXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS 2832
               F + L  +V KEG    F C +     P  ++ W   N PL    R   +       
Sbjct: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQV 217

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            L+I    ++D G+YTC   N  G A+ S  L   G
Sbjct: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 12/194 (6%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGE 4045
            E  T KFE ++   G P  +V W  NG+P+    RF       G  ++    V+ ED G+
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 4046 YLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEES 4105
            Y C ATN  G  +    +   G     +  QL + + S        AS   T   +  E 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE- 158

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGM 4164
               CPP F +    V V+EG+  RF C++TG P+P+V WL     +   +R  ++  +GM
Sbjct: 159  ---CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGM 215

Query: 4165 YHFDIPKTRQYDTG 4178
               +I    Q D G
Sbjct: 216  QVLEIHGVNQDDVG 229



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 69/232 (29%), Positives = 101/232 (43%), Gaps = 27/232 (11%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V+  AP F+  +KD  V E Q   F  +    G P  R+ WL NG PI+ + R T   + 
Sbjct: 509  VMEVAPSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EA 563

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G   L+++   PED GTYTC A N LG+   S+ + V  K S                  
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS------------------ 605

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             S + +    V  +   AP F+  L+   K+ +G       ++   P P   V W  NG 
Sbjct: 606  -SRKSEYLLPVAPSKPTAPIFLQGLS-DLKVMDGSQVTMTVQVSGNPPP--EVIWLHNGN 661

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             +Q    +         +L I  V+ ED+G YTC+A N+ G+  +   L VQ
Sbjct: 662  EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 14/252 (5%)

Query: 1970 DDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            D   + E P F  P +N  + EG     E  +    +P  +V W+ NG+P+  G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLD 82

Query: 2030 YDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYL-DTLDEQRLKK 2087
                G  +L I   + ED G Y C+ATN  G    T  + V+      L   +  + L  
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                   E    I  E P   P F T L  +  +KEG    F C++     P +T  W  
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKITGRPQPQVT--WLK 196

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG---- 2203
                ++   R   +   G   L+I     +D G Y C   N  G+A  +  L + G    
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256

Query: 2204 HRNIILDTQHPN 2215
            +R+ + +T+  N
Sbjct: 257  NRSFVRETKATN 268



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 74/305 (24%), Positives = 117/305 (38%), Gaps = 21/305 (6%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P FE   ++    +    KF  ++ G P P V+W  +  P V   + S+   E  G   L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTP-VRRQEGSIEVYEDAGSHYL 472

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            + +    D G Y+CTA N  G+  CS  +Q E               +  +  +E + +
Sbjct: 473 CLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCA-VIEGQDF 531

Query: 192 GTQGYT--TEQSRQT-----QKVAYTNGTDHSSTDDFKV------DTFEYRLLREVSFRE 238
             Q     T   R T     Q + Y   T  +   +  +      D   Y  L E +  +
Sbjct: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591

Query: 239 SITKRYVGESDVQISTEIDRSLGPVSP-----PKIAQKPRNSKLQEGADAQFQVQLSGNP 293
                +V   + + S + +  L PV+P     P   Q   + K+ +G+     VQ+SGNP
Sbjct: 592 VSCSAWVTVHEKKSSRKSEYLL-PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
            P V W  NG  +  S            +L ++     D+G YT  A N  G + T   L
Sbjct: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710

Query: 354 AVESP 358
            V+ P
Sbjct: 711 TVQEP 715



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 61/225 (27%), Positives = 102/225 (45%), Gaps = 13/225 (5%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P    P F+   R    + EG TA FE +V    +P  ++ ++ NG+ + S  RF +   
Sbjct: 28   PLTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCG 84

Query: 2297 F-GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRE 2355
              G  SL I     ED G+Y+ +A N  G     +++ +T +GS   +  +P   + + +
Sbjct: 85   IRGTFSLVIHAVHEEDRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2356 LESAEPFK-RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
              SA   + RP I        P F   L  +  ++EGQ   F C++   G P  +V W +
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKI--TGRPQPQVTWLK 196

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                ++ S+R++ +   G   + I  V  +D GVY C   N  G+
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 26/240 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++ P F    +   + E   A+FE    G P P + W+R   PI +   F +      + 
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG----------------- 4509
             L+I  V  ED   +   A N  G  + +  L VE    +  G                 
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149

Query: 4510 -------GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                   G  PP F      V V  GQ+ R   K+TG     V WLK    +QP  R  +
Sbjct: 150  ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE-CVVSLPATKDKPKPQTKAANA 4621
             E++G   L I      D G Y C+ +N +G+A   AE  +  L +       +TKA N+
Sbjct: 210  SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 57/224 (25%), Positives = 99/224 (44%), Gaps = 10/224 (4%)

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
            + + D  C      T D  K ++++    P   + L+D  VAEG+ +   C++   P  T
Sbjct: 1070 DVKNDVNCKRGHAGTTDNEK-RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W    K +K +K+  +S+     ++ I +A PED G YKCVA N AG+   + ++ V 
Sbjct: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD 1188

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQ--ITSKIKPTIQWLREGALIPET---PDFQ 4768
                ++N  A   ++        P    T+   T K KP  +   + A+ P+    P+ Q
Sbjct: 1189 DAPASENTKA-PEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  G  +V L G      T   TC       Q++ S  + V++
Sbjct: 1248 KVRAG-ESVELFGKV--TGTQPITCTWMKFRKQIQESEHMKVEN 1288



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 67/227 (29%), Positives = 97/227 (42%), Gaps = 27/227 (11%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F + L     + EGQ    +C +   P P  R+ W  NG+ +Q     R++ + G A
Sbjct: 513  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 566

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
             L I     ED G YTC A N LGQ   S  + V  K+S            K +YL   +
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----------SRKSEYLLPVA 616

Query: 1963 RYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ 2022
              K            P F + + + +V +G  V +  T+    +P   V W  NG  +Q+
Sbjct: 617  PSKPTA---------PIFLQGLSDLKVMDGSQVTM--TVQVSGNPPPEVIWLHNGNEIQE 665

Query: 2023 GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
               F         +L I   + EDTGTY C+A N+ GE  T + + V
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 109/491 (22%), Positives = 182/491 (37%), Gaps = 27/491 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+ P  N   + EG     E R+   G P  +V W  NG+ +T G RF          
Sbjct: 33   PAFILPPRNLC-IKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 1237 LDIIHAT-SADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
              +IHA    D G+YT  A N  G+   + +   +E S      Q  Q +    L +  +
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVT-VELTVEGSFA---KQLGQPVVSKTLGDRFS 145

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                + R  I     P+F+  L  +   EG      C++   G    +V W     P++ 
Sbjct: 146  ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQP 203

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              R   + +     L++  V  +D GVYTC   N  G+A  S  L +       L+S + 
Sbjct: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG-----LDSANR 258

Query: 1416 SGLEKIQYLEDTSRYKKTDIID-ESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            S + + +      R + T++I  ES         + K+  +   G    +    +P    
Sbjct: 259  SFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
              K+E  K+  P T      P+      ++ +     +         V     +E     
Sbjct: 319  ESKLESCKD-SPRTAPQ--TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA 375

Query: 1535 TCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
              R  T   R    + GL    V+  ++   R  M  +  +  P   +  ++ E+KE Q 
Sbjct: 376  PPRPATFPTR----QPGLGSQDVV-SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET-NNFGFVALDIMSCLPEDSGTYTCR 1653
              F   +  +     +V W+    P++      E   + G   L ++     DSGTY+C 
Sbjct: 431  VKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488

Query: 1654 AINALGEAVTS 1664
            A NA G+   S
Sbjct: 489  ASNAQGQVSCS 499



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 1/98 (1%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLR 4681
            P   + ++D  V EG A  F CKI G P P V W+K D+ I+ S++FQ+    D   +L 
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
            IS+   +D+  Y C A NS G  T  A+L V   ++ +
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 69/245 (28%), Positives = 100/245 (40%), Gaps = 29/245 (11%)

Query: 1298 TKQVREDITVMQ-APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            T QV E + VM+ AP FS  L +   +EG +  L+C ++  G    R+ W  NG+PI+  
Sbjct: 501  TLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA 557

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
               R   E     L +    PED G YTC A N LG+   S  + V  KK          
Sbjct: 558  ---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK---------- 604

Query: 1417 GLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL 1476
               K +YL   +  K T          P F+     ++ V++G  V    ++    +   
Sbjct: 605  SSRKSEYLLPVAPSKPT---------APIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPP 652

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            +V W  NG  +     F         +L I ++  ED+G YTC A N  G       LT 
Sbjct: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712

Query: 1537 RSTTD 1541
            +   D
Sbjct: 713  QEPHD 717



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 71/270 (26%), Positives = 105/270 (38%), Gaps = 23/270 (8%)

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G V  VA +   +T+     + ++   +  AP F+     L ++EG       R  G P 
Sbjct: 2   GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 520 PRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P++TW ++G PI       +     G  +L I      D   Y C A N +G     AR 
Sbjct: 62  PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG-----ARQ 116

Query: 579 YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQ 638
                       K+L  P  +K                 VE  RP I  GE      PP+
Sbjct: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSASA-------VE-TRPSI-WGE-----CPPK 162

Query: 639 FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDM 698
           F   L  V   EG    F  +I   G P  ++ WLK    ++ S+R +   + G   L++
Sbjct: 163 FATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220

Query: 699 LSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +N  D G YTC  V+ +G A   A L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 1/93 (1%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYT 4570
            V P F+ T +++ V  G   R D K+ G    +V W K+ + ++     +I  +EDG  +
Sbjct: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1866

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            L+I +    D  KY C A+NS GEA C AE +V
Sbjct: 1867 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 64/250 (25%), Positives = 102/250 (40%), Gaps = 11/250 (4%)

Query: 3125 ATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKI 3183
            A++   +  +SV    VD     + P F    +N+  +K+G +A FE  V    +P  ++
Sbjct: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QV 64

Query: 3184 EWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             W+ NGQP+    R        G   L I      D G+Y C A N  G    + T+   
Sbjct: 65   TWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELT 122

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +G    +  QP     + +  S    + + PS     PPKF T++  V  + EGQ   F
Sbjct: 123  VEGSFAKQLGQPVVSKTLGDRFSASAVETR-PSIWGECPPKFATKLGRVV-VKEGQMGRF 180

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
              ++     P  +V W      L    R       G+ +L+I    +++ G Y C+  N 
Sbjct: 181  SCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238

Query: 3363 LGRDSTKANL 3372
             G+ S  A L
Sbjct: 239  SGKASMSAEL 248



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 4/123 (3%)

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
            +K++  ED S+       E   +  P F   +    ++ EG +A ++C+IE YPDP   V
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPE--V 1840

Query: 1879 EWYFNGKVLQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             W+ + + ++    ++   D  G  +L I  V G+D  +YTCKA+N+LG+A  +  L V+
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900

Query: 1938 SKE 1940
            + E
Sbjct: 1901 TME 1903



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/243 (23%), Positives = 99/243 (40%), Gaps = 35/243 (14%)

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-- 425
           S +I+ T       R++      AP F+   ++  + EG   +F+ RV G P P+VTW  
Sbjct: 9   SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68

Query: 426 ----------FINDRQIRDDYN---HKILVNESGNHALMITN--------VTLSDSG--- 461
                     F+ D  IR  ++   H +   + G +    TN        V L+  G   
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128

Query: 462 ------VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
                 VV+    ++   +A + R ++  +     PKF  +   + V+EG+    + +  
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGE---CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           G P P++TW K  VP+ P+  + +    G   L+I      D   Y C   N +G  +  
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245

Query: 576 ARL 578
           A L
Sbjct: 246 AEL 248



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/217 (26%), Positives = 91/217 (41%), Gaps = 14/217 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGL 2580
            EG  A +E RV   G P  +  W+ NG  +  G RF       G  +L I++V   D G 
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2581 YMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQI--QLKEAAMNKVPEMFVDTGV 2638
            Y C+A N +G                  Q  +P   + +  +   +A+   P ++ +   
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFA--KQLGQPVVSKTLGDRFSASAVETRPSIWGEC-- 159

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
               P F T L     + EGQ      ++  R  P  ++ W K  V L   AR+  +   G
Sbjct: 160  --PPKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNG 214

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            +  L I+ +  DD G+YTC   N  G+A  +A + I+
Sbjct: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 6/119 (5%)

Query: 1415 PSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            P   EK++  ED S+     + +E   +KP F    + +E V+EG    F+CK+E   D 
Sbjct: 1780 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1838

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
              +V WFK+ Q +     F+  +D  G  +L I D+  +D   YTC+AVN +G  E +C
Sbjct: 1839 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATC 1893



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 6/103 (5%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            + EE+P  +P F   +  LE + EG  A F+C++E   DP +   WF + Q IR    ++
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQ 1856

Query: 2160 TTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              +D  G  +L I     +D   Y CKA N LGEA  TCT ++
Sbjct: 1857 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCTAEL 1897



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 67/267 (25%), Positives = 104/267 (38%), Gaps = 22/267 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F++V KD   I EGQ    + S+   G     I W  NG+ I+ +   R+    G+  
Sbjct: 514  PSFSSVLKDCAVI-EGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK-----------PRFTTHIQ 3156
            L I      D GTY+C A N  GQ   S  +   +K   +K           P     +Q
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             +  LK    +    TV    +P  ++ W HNG  ++ S             L I     
Sbjct: 628  GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687

Query: 3217 HDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPST 3276
             D+G Y C A+N  GE  T+A +          +  QP  ++K R + +  G        
Sbjct: 688  EDTGTYTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWFISKPRSVTASLGQSVLISCA 743

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFE 3303
             + +P   +  ++D   L +  + HFE
Sbjct: 744  IAGDPFPTVHWLRDGKALCK-DTGHFE 769



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 53/219 (24%), Positives = 93/219 (42%), Gaps = 30/219 (13%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLR 4681
            P  I P ++  + EG   +F  ++ G P P V W++ G  +    ++         ++L 
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4682 ISEAFPEDEGDYKCVAYNSAG--RVTVAAKLK------VTQPDQADNL------------ 4721
            I     ED G Y C A N +G  +VTV   ++      + QP  +  L            
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4722 PAL---------TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
            P++         T L  +VV EGQ  +F  +IT + +P + WL+    +  +    +  +
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                VL I    ++D G +TC     +G+   SA+L ++
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 59/227 (25%), Positives = 96/227 (42%), Gaps = 27/227 (11%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++ AP F++ LK    ++EGQ   L+  V  R  P  +I W  NG  +      +ST + 
Sbjct: 510  MEVAPSFSSVLKDC-AVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 563

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI-EDRHWLLGESLHPDSLDRIGAL 2756
            G+  L I     +D G YTC A N LG+   +A + + E +     E L P +  +  A 
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA- 622

Query: 2757 XXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL 2816
                              +F+  L+++   +G  +     V+ S +P  ++ W  N   +
Sbjct: 623  -----------------PIFLQGLSDLKVMDGSQV--TMTVQVSGNPPPEVIWLHNGNEI 663

Query: 2817 PSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +      +  SL I   + ED+G YTC+A NS G   T   L
Sbjct: 664  QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 62/232 (26%), Positives = 94/232 (40%), Gaps = 28/232 (12%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   LK    ++EGQ   F  +   +      + W  NG+ I  A   ++  + G   
Sbjct: 514  PSFSSVLKDC-AVIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I     ED G YT +A NA G+   SA +TV  + S                  +S++
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----------------RKSEY 611

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            + P   +     + P+F+Q LS+   V +G  + +  ++   G+P   V W HNG  +  
Sbjct: 612  LLP---VAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQE 665

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
               F         +L I      DTG YT  A N  G   T A++ V E  D
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 5/143 (3%)

Query: 2319 AINALGHCTS-AISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
            A+ A+G  +S A+   ++ + S       P   EK+   E         + E     +P 
Sbjct: 1751 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1810

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSM 2436
            F++ +++++ + EG  A FDC++    DP  +V WF++++ I +S      +D  G  S+
Sbjct: 1811 FSKTIRDLE-VVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSL 1867

Query: 2437 TISHVRDEDEGVYMCRASNLLGE 2459
             IS V  +D+  Y C+A N LGE
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGE 1890



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 54/227 (23%), Positives = 89/227 (39%), Gaps = 11/227 (4%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            + EG+ L L+ QV   +DP   I W  NGK L+      L+ +    ++ +      D G
Sbjct: 1109 VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166

Query: 2983 IYTCKAYNKRGEAFTSSTVYC----TSKDNLIERTQHPKGTEGLEKIQNLED--SLRKEP 3036
            +Y C A N  G+A  S  V       S++      +  +    L  +   E   +++K+P
Sbjct: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
              +       PP+    F +   +  G+       +  TG Q +   W    K I+ S  
Sbjct: 1227 APKTPPKAAMPPQIIQ-FPEDQKVRAGESVELFGKV--TGTQPITCTWMKFRKQIQESEH 1283

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            ++   +     L IL  +    G Y+    NK G  +  V L  VDK
Sbjct: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 44/140 (31%), Positives = 66/140 (47%), Gaps = 5/140 (3%)

Query: 4374 GDKEITRKITSTETTE-IEHKAQTQERVVEGPV--KPSKPPIFTKKMQPCRVFEHEQARF 4430
            G K  T   TS    E +E +    +  +E     KP   P F+K ++   V E   ARF
Sbjct: 1769 GRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARF 1828

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489
            + + +G P P + W++++  I+ S  FQI +       LII  V  +D A +   A N  
Sbjct: 1829 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1888

Query: 4490 GTAKCSANLVVEEKRRQGRG 4509
            G A C+A L+V E   +G G
Sbjct: 1889 GEATCTAELIV-ETMEEGEG 1907



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 67/228 (29%), Positives = 98/228 (42%), Gaps = 28/228 (12%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F + +KD  ++ EG    F  +    G    R+ WL +G+P++ + R T     G   
Sbjct: 514  PSFSSVLKD-CAVIEG--QDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAE 567

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I+     D G YTC A NA+GQ + SA +T+  KK             K +YL   + 
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKSEYLLPVAP 617

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
             SK T         P FL  L    K+++G       +V    +    V W  NG +I  
Sbjct: 618  -SKPT--------APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 665

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            +            +L I  V  ED+G YT  A N+AGE +  A +TV+
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 47/155 (30%), Positives = 76/155 (49%), Gaps = 5/155 (3%)

Query: 710  TCRAVSATGVAETKAVLH-VTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ 768
            T  AV A G   + A++  ++ R +   +   P   + ++  ED S+   +   EE+   
Sbjct: 1748 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1807

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827
            +P F + ++DL E+ EG  A F+ ++    DP   V W+KD + I  S      ++  G 
Sbjct: 1808 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             SL I  +  +D   YT +AVN LGEA  TA + V
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 46/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 983  TCRAYNAIGQATTSANLTIVT-KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            T  A  AIG+ ++ A ++ ++ +K        P   EK++  ED S+       E K   
Sbjct: 1748 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1807

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGY 1100
            KP F   ++   ++VEG +A F+ ++E   D    V W+ + + I  +   Q  Y + G 
Sbjct: 1808 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPD--PEVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             +L I+ V  +D   YT  A N+ GEA  +A + VET
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1901



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F +  ++    +G  A+F+ K+ G P P V W +    + E   + + Y+E  G+ SL
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1867

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            +I  +   D+ +YTC A N  GEA C+
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCT 1894



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 20/239 (8%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P FI   ++  ++E    +FE RV    +P  ++ W+RNG+ + SG R+     + G  S
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  V+ ED G+Y C A N  G    + T+      ++ ++    + + +      +  
Sbjct: 91   LVIHAVHEEDRGKYTCEATN--GSGARQVTV------ELTVEGSFAKQLGQPVVSKTLG- 141

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
               ++++    T   ++    + PP+F T++  +  + E +  +F C++   G P  +V 
Sbjct: 142  --DRFSASAVETRPSIWG---ECPPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVT 193

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W     PL    R +     G   +    V  +D G Y C   N  G     A +   G
Sbjct: 194  WLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 12/238 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F   ++D+ VAE +    + ++    DP   + W  NG  ++ +  +    +    +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-------QSKASLQLESQHESALQKIQ 1822
            ++++   PED G Y C A N+ G+A  S  + V        +KA      + +S+L  + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1823 QLEDSSRYQRREDVEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
              E  +  +++   +     A P  I Q     K+  G+S     ++     P +   W 
Sbjct: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG-TQP-ITCTWM 1272

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
               K +Q     +  N    + L IL    E  G YT    N LG   + + L V  K
Sbjct: 1273 KFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 3/130 (2%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +L   ED S+    +  +E     P F+  ++D+ V E  AA F+ ++    DP+  V W
Sbjct: 1785 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1842

Query: 1747 LRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             ++   I  S      +D  G  +L +  V  +D   YTC+A+N LGEA  ++ L V++ 
Sbjct: 1843 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902

Query: 1806 ASLQLESQHE 1815
               + E + E
Sbjct: 1903 EEGEGEGEEE 1912



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 38/120 (31%), Positives = 62/120 (51%), Gaps = 5/120 (4%)

Query: 1953 EKIQYLEDDSR-YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
            EK++  ED S+ +  AV ++   V KP F K I++ EV EG     +  +    DP   V
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHV-KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EV 1840

Query: 2012 EWYCNGRPVQQGHRFKTTYDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             W+ + + +++   F+  YD  G  +L I     +D   Y CKA N++GEA  T+ + V+
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 70/311 (22%), Positives = 117/311 (37%), Gaps = 34/311 (10%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            ++EGQ   L+  V  +  P  +I W  NG+ ++     + T + G   L + D    D G
Sbjct: 525  VIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHG 579

Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDD 3042
             YTC A N  G+   S+ V           T H K +    K + L      +P      
Sbjct: 580  TYTCLAENALGQVSCSAWV-----------TVHEKKSS--RKSEYLLPVAPSKP------ 620

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
                 P F     D+  +   Q+     ++  +G+    + W +NG  I+ S        
Sbjct: 621  ---TAPIFLQGLSDLKVMDGSQVT---MTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
                 L I      D+GTY+C A N  G+      L   +   G +P F +  +++    
Sbjct: 675  GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA-S 733

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST-RIKTVSDFGFVVLDIAYTQNHDSGE 3221
             GQS    C +    DP   + W  +G+ +   T   + + +     L +   Q   +G+
Sbjct: 734  LGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791

Query: 3222 YVCRAYNKYGE 3232
            Y     N+ GE
Sbjct: 792  YEILLKNRVGE 802



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 61/212 (28%), Positives = 85/212 (40%), Gaps = 26/212 (12%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG     +C V     P +T  W  NGQ I+     R+T + G   L I     ED GTY
Sbjct: 527  EGQDFVLQCSVRGTPVPRIT--WLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 581

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPP 2242
             C A N LG+   +C+  V  H             +  R+ E       + V   K + P
Sbjct: 582  TCLAENALGQV--SCSAWVTVHEK-----------KSSRKSEYL-----LPVAPSKPTAP 623

Query: 2243 RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
             F+  L     V +G       QV    +P   + + HNG  +Q +  FH        SL
Sbjct: 624  IFLQGL-SDLKVMDGSQVTMTVQVSG--NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             IQ   PED G Y+ +A N+ G   +   +TV
Sbjct: 681  CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 55/235 (23%), Positives = 92/235 (39%), Gaps = 14/235 (5%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F + L ++   EG  + L+C++    D    + W  NGK +KT      + E    +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV------IAKKDLILESQHP-SGLEKIQ 1422
            + +    PED G+Y C A N  G+A  SC + V         K   ++S+ P S L  + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1423 YLEDTSRYKKTDI--IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEW 1480
              E  +  KK           + P+ +  P+  + V  G+ V    K+       +   W
Sbjct: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKV--TGTQPITCTW 1271

Query: 1481 FKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             K  + +      +  +      L I+    E  G YT    N +G+ +    LT
Sbjct: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1326



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 8/123 (6%)

Query: 43  HFTRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPV 102
           H ++   +   S  D  P+T   P    PP      +N    +G  AKFEG++RG P P 
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEA-PAFILPP------RNLCIKEGATAKFEGRVRGYPEPQ 63

Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           V+W R   P+    ++ +    + G  SL+I  +   D G+YTC A N  G    +V + 
Sbjct: 64  VTWHRNGQPITSGGRFLLDCGIR-GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122

Query: 163 PEG 165
            EG
Sbjct: 123 VEG 125



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 63/218 (28%), Positives = 91/218 (41%), Gaps = 28/218 (12%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F + L+    V EG+    +C V     P  RI +  NG+ +Q A     T + G   
Sbjct: 514  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYARS---TCEAGVAE 567

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L IQ  +PED G Y+  A NALG  + +  +TV  K S    S++ E             
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSE------------- 610

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            +  P  P   T   P+F Q L ++  + +G       ++   G+P  +V W  N   I++
Sbjct: 611  YLLPVAPSKPT--APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 665

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S            S+ I  V  ED G Y C A N  GE
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 58/243 (23%), Positives = 97/243 (39%), Gaps = 17/243 (6%)

Query: 258  RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            RS    + P   QK ++  + EG     Q Q+S +P   + W  NG+ L  + K  I++ 
Sbjct: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1148

Query: 318  HNHT-TLRVRNTQKSDSGHYTLLAENPNG-----CIVTSGYLAVESPTESYVQDQRSQYI 371
                 ++ +      D G Y  +A+N  G     C VT         T++     R    
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208

Query: 372  TDTQQRETEERIEISEK---------ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            +      TE    + +K         A+ PQ ++  +D+ V  G+      +VTG     
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             TW    +QI++  + K+  +E+G+  L I        G  T +  NK G    Q  L V
Sbjct: 1269 CTWMKFRKQIQESEHMKVENSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327

Query: 483  IEK 485
            ++K
Sbjct: 1328 VDK 1330



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 35/237 (14%)

Query: 3558 PEFTTTPSDLILSENSSAHFEC--RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            P F++   D  + E      +C  R  PV     R+ W  NG+P+      ++  + G  
Sbjct: 514  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVP----RITWLLNGQPI---QYARSTCEAGVA 566

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I      D G YTC A N  G+  VSC   V              H K  +   + L
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQ--VSCSAWVT------------VHEKKSSRKSEYL 612

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
                     + +   KP  P F   + D + V +G  V    +V   G+P   + W HNG
Sbjct: 613  ---------LPVAPSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 660

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
                     H        +L I  ++  D G YTC A N  G   T A +T     D
Sbjct: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 4/154 (2%)

Query: 1251 TVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            T  AV  +G   + A++  +  R        +    E+++  ED ++   +   +     
Sbjct: 1748 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1807

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD-YV 1368
             P FS+ + ++E VEG+    +C+++   D    V WF + + I+    F+  Y+ D   
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNC 1865

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L +  V  +D   YTC+A N LGEA  +  L V
Sbjct: 1866 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 60/244 (24%), Positives = 100/244 (40%), Gaps = 16/244 (6%)

Query: 2226 QGHSTRIEVE---EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
            +GH+   + E   E + + P F  +L+   HV EGK    +CQV    DP   I +  NG
Sbjct: 1079 RGHAGTTDNEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSS--DPPATIIWTLNG 1135

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV----TAKG 2338
            K L++     ++ +    S+ I+  +PED G Y   A N  G    +  +TV     ++ 
Sbjct: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195

Query: 2339 SIISE--SQRPE-GLEKIRELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTA 2394
            +   E  S+RP+  L  +   ES    K+   P+ P     P           ++ G++ 
Sbjct: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255

Query: 2395 HFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
                ++   G   +   W +  K I++S  +   +      +TI   R E  G Y     
Sbjct: 1256 ELFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1313

Query: 2455 NLLG 2458
            N LG
Sbjct: 1314 NKLG 1317



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 3/134 (2%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + +  + +G+     + E   S+    PPK A K     ++EG   +F  +++G P+P+V
Sbjct: 133 QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-- 355
           TW K    L  S +  +   +    L +    + D G YT L  N +G    S  L++  
Sbjct: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252

Query: 356 -ESPTESYVQDQRS 368
            +S   S+V++ ++
Sbjct: 253 LDSANRSFVRETKA 266



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 61/232 (26%), Positives = 91/232 (39%), Gaps = 28/232 (12%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F+  +KD   V EG      C V   G P  RI W  NG+P        +  + G   
Sbjct: 514  PSFSSVLKD-CAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPI---QYARSTCEAGVAE 567

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L I      D G YTC A N  G  + +A +T   K+            S  K + L   
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK------------SSRKSEYL--- 612

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
             +  AP +     T P F+  +    ++  +G +    V+   +P   + W  NG  +  
Sbjct: 613  -LPVAPSK----PTAPIFLQGLSD--LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
               +         SL I  V+ ED+G Y C A N  GE  T+A ++ ++  D
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 4/100 (4%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GY 966
            KP F   I+D + + EG  A F+ ++E   D    V W KD + +  S      ++  G 
Sbjct: 1808 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
             +L I  V   D   YTC+A N++G+AT +A L + T ++
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 55/224 (24%), Positives = 87/224 (38%), Gaps = 12/224 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG  +  +C V  S DP   I W  N K L +      + + S  S+ I
Sbjct: 1100 FKQKLQDVHVAEGKKLLLQCQV--SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQ-----GKAGLEAVEQA 2890
                 ED G+Y C A N  G A  S  +    D     +T+ P+      K+ L  V   
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQV-TVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216

Query: 2891 E-EARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949
            E +A + K   P  P      P+ II    + ++  G+ + L G+V       +   W  
Sbjct: 1217 ESDATVKKKPAPKTPPKAAMPPQ-IIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMK 1273

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
              K +++    K+ +      L ++   +   G YT    NK G
Sbjct: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 4/124 (3%)

Query: 2613 PESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            P + E+++ +E       E   +      P F+  ++  + +VEG     + ++E   DP
Sbjct: 1780 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1838

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
              ++ WFK+  ++      +  +D  G  +L I+ +  DD   YTCKA N LGEA  TA 
Sbjct: 1839 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1896

Query: 2732 IKIE 2735
            + +E
Sbjct: 1897 LIVE 1900



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 5/101 (4%)

Query: 3687 IEDEKPN-PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
            + +EKP+  P F+  I+D ++V EG    FDC++E   DP   + WF + +         
Sbjct: 1800 VAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQ 1856

Query: 3746 -TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               ++ G  +L I  +   D  +YTC+A N  G AT TA++
Sbjct: 1857 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 4/120 (3%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            EKL++ ED      +   EE+    P F+  + ++E + EG  A F+ ++    DP  +V
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV-EGSAARFDCKIEGYPDP--EV 1840

Query: 3455 EWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             W+ + +S++    F+  + + G   L IS    +D  +Y C+A N+ GEA  TA + V+
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 55/226 (24%), Positives = 90/226 (39%), Gaps = 14/226 (6%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F  +L     ++EG+    +C++    DP   + W  NGK L++      S +    
Sbjct: 1097 APAFKQKLQD-VHVAEGKKLLLQCQVSS--DPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-------QSKESIIRDSQHESALEKI 1955
            ++ I     ED G Y C A N+ GQA  S ++ V        +K   ++  + +S+L  +
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213

Query: 1956 QYLEDDSRYKR--AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW 2013
               E D+  K+  A +        PQ  +  ++ +V  G  V L   +T     T    W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT--CTW 1271

Query: 2014 YCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
                + +Q+    K         L IL A  E  G Y     N +G
Sbjct: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 1/87 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYE 4785
            +RD+ V EG  A+F  +I     P + W ++   I E+  FQ+ + E  N  L+I +   
Sbjct: 1815 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1874

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +D   +TC+A  + G+   +A+L+V++
Sbjct: 1875 DDDAKYTCKAVNSLGEATCTAELIVET 1901



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 52/251 (20%), Positives = 93/251 (37%), Gaps = 10/251 (3%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E   E     P F + LQD+  + EG+    + Q++  SDP   + W  +G+ +  +  I
Sbjct: 1088 EKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFI 1144

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV----AARSTVTADLGIP 875
                     S++I     ED G Y   A N  G+A  +  + V    A+ +T   ++   
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935
              +  +                     P++   P+     +DQ  ++ G       ++  
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ-KVRAGESVELFGKVT- 1262

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             G   +   W+K  + ++ S  +    +     LTI +      G YT    N +G    
Sbjct: 1263 -GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQA 1321

Query: 996  SANLTIVTKKD 1006
              NLT+V K D
Sbjct: 1322 QVNLTVVDKPD 1332



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 5/108 (4%)

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            E  +++ +  +    +E+P V   P F   I+   V E    RF+C++E   DP+  + W
Sbjct: 1787 ESEEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1842

Query: 3866 YRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            +++ + +     ++  YD  G  SL I  V  +D  +Y C+AVN  GE
Sbjct: 1843 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 58/258 (22%), Positives = 90/258 (34%), Gaps = 10/258 (3%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G++GT D        G  P F     D+ ++E      +C++   +D    + W  NGK 
Sbjct: 1080 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKT 1137

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI--IL 3657
            L T   +    +     + I      D GLY C A N  G+A  SC++ V          
Sbjct: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1197

Query: 3658 EPQLPSHF-KSGTESIQKLEE--TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVH 3714
             P++ S   KS    +   E   T+ K+       +   PP+  ++  ++  V  G  V 
Sbjct: 1198 APEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI-IQFPEDQKVRAGESVE 1256

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
               +V   G   +   W    +       +   N      L I        G YT    N
Sbjct: 1257 LFGKV--TGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVEN 1314

Query: 3775 KWGSATTTAKITCSAKRD 3792
            K GS      +T   K D
Sbjct: 1315 KLGSRQAQVNLTVVDKPD 1332



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 32/232 (13%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F + ++D   ++EGQ    +  +     P  ++ W  NG+ + +    R+  + G+  
Sbjct: 514  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401
            L I     E+ G Y C+A N LG+ S  A +    K++      L               
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL--------------- 612

Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461
                      V   K  AP+F   LS+++ + +G       +++    P  +V W  NG 
Sbjct: 613  --------LPVAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVSGNPPP--EVIWLHNGN 661

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             ++    F          L I   +PED+G Y C A+N+ GE  T A + VQ
Sbjct: 662  EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + E+R E   +  AP F +  QD  V EGK     C+V+  P   + W +N + ++    
Sbjct: 1086 DNEKRSE--SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-K 1142

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE---KEQVVAPKFV 494
              IL  E    ++ I      D G+  CVA+N +G+    C++ V +    E   AP+  
Sbjct: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202

Query: 495  ER 496
             R
Sbjct: 1203 SR 1204



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 57/243 (23%), Positives = 98/243 (40%), Gaps = 19/243 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L+  + + EG+    + +V   SD   T+ W  NGK + +   I    +    +
Sbjct: 1098 PAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            + I     ED G+Y  VA+N AG+A+ S  +TV+   + + +   +    K+R  + S  
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT---KAPEMKSRRPKSS-- 1209

Query: 1163 VEPMYQIEEIS--KSKPVFVQP--LSNPPPV---SEGKNIHLECRLEPMGDPT----MRV 1211
            + P+   E  +  K KP    P   + PP +    E + +     +E  G  T    +  
Sbjct: 1210 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1269

Query: 1212 EWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             W    + +      K         L I+ A     G YT+   N LGS      + V++
Sbjct: 1270 TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329

Query: 1272 RSD 1274
            + D
Sbjct: 1330 KPD 1332



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 7/137 (5%)

Query: 2201 VAGHRNIILDTQHPNGLEKIRQLE--AQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            ++G ++       P   EK+   E  +Q     +  E+P + P  + ++      V EG 
Sbjct: 1767 LSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP--YFSKTIRDLEVVEGS 1824

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSV 2317
             A F+C++E   DP   + ++ + ++++ +  F I +D  G  SL I     +D  +Y+ 
Sbjct: 1825 AARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1882

Query: 2318 KAINALGHCTSAISMTV 2334
            KA+N+LG  T    + V
Sbjct: 1883 KAVNSLGEATCTAELIV 1899



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 3/131 (2%)

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
            E+++  ED S+     + +E     P  + +++++E+ EG  A F+ ++    D   +V 
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVV 1841

Query: 1613 WYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
            W+ +++ ++    F  + +  G  +L I     +D   YTC+A+N+LGEA  +   IV +
Sbjct: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1901

Query: 1672 KKSIYLESQHE 1682
             +    E + E
Sbjct: 1902 MEEGEGEGEEE 1912



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           P +P+ PIF Q   + +   G       ++ GNP P V W      + E   +   + ++
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQR 674

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
               SL I+++ P D G YTC A N  GE
Sbjct: 675 GTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/231 (24%), Positives = 89/231 (38%), Gaps = 28/231 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P F+ VL   + + EGQ    +  V   G P  R  W +NG  ++     R+T + G   
Sbjct: 514  PSFSSVLKDCAVI-EGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L I   +  D G Y C A N  G                        +W  +  K+++  
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCS-------------------AWVTVHEKKSSRK 608

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                + V      APIF   L    K+++G  V +  QV     P  ++ W  NG  +  
Sbjct: 609  SEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQVTMTVQVSGNPPP--EVIWLHNGNEIQE 665

Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
                         +L I  +  +D+G YTC+A N  GE  + A + +++ H
Sbjct: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 52/242 (21%), Positives = 89/242 (36%), Gaps = 12/242 (4%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            E +G AP F   L ++ ++ EG+    + +++   DP   + W  NGK+LK  ++F    
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT-TKFIILS 1147

Query: 3474 DFGFVI-LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ---GKRNIILESQLPKGME 3529
              G +  + I    PED G Y C A N+ G+A  +  + V       N        +  +
Sbjct: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207

Query: 3530 GTIDKIAALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
             ++  +   E  +       P+   ++  PP+    P D  +    S     ++      
Sbjct: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQ 1265

Query: 3588 SMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
             +   W    K +     +K  N      L I    Q   G YT    N+ G       L
Sbjct: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325

Query: 3648 QV 3649
             V
Sbjct: 1326 TV 1327



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F+  L  +  M+G ++    ++   G+P  ++ WL NG  I+ S  F    R    SL
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +  +  +D+G YTC A ++ G   T+AVL V
Sbjct: 681 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIK 4749
            GD K VA +   + +++              PA + P R++ + EG  A+F+ ++    +
Sbjct: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            P + W R G  I     F ++  G      L+I   +EED G +TC AT  +G  + + +
Sbjct: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 4808 LVVK 4811
            L V+
Sbjct: 121  LTVE 124



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 3/116 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMHDFGYVA 1769
            P F    +   V ENQ   F   +   G PK  V W   G P+      +    D G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            L +      DSGTY+C A N  G+   S TL V+  A +++     S L+    +E
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 57/237 (24%), Positives = 91/237 (38%), Gaps = 33/237 (13%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F   L+D   + EG++  F  Q +    P  R+ W  +G+PI  +    S    G   
Sbjct: 514  PSFSSVLKDCAVI-EGQD--FVLQCSVRGTPVPRITWLLNGQPIQYAR---STCEAGVAE 567

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L+I     ED G+YT  A N LG+   +A + V  + +         +  Y+        
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-------SRKSEYLLPVA---- 616

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                         P     P F   + D + + +G       ++   G+    V WL +G
Sbjct: 617  -------------PSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 660

Query: 950  RPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
              ++ S            +L I+ V   D G YTC A+N+ G+  T A LT+    D
Sbjct: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 630  EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            E++ +  P F   ++ +  +EG    F+ +IE   DP  ++ W K+ QSI  S  F   +
Sbjct: 1802 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDY 1859

Query: 690  -RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
               G  SL +  +   D  +YTC+AV++ G A   A L V
Sbjct: 1860 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 27/226 (11%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F   LK    +EG     +  +   G P  +I WL NGQ I+ +    S    G   L
Sbjct: 514 PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 568

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
            +     +D G YTC A +A G     A + V  + +  +                 S+Y
Sbjct: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK-----------------SEY 611

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
               +  + T+  P F++ L DL ++ +G       Q++   +P   V W  +G  I  S
Sbjct: 612 LLPVAPSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 666

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                       SL I  +  ED G+YT  A N  GE  + A + V
Sbjct: 667 EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 58/229 (25%), Positives = 81/229 (35%), Gaps = 27/229 (11%)

Query: 3988 METTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYL 4047
            +E   F  Q +  G P  ++ W  NG+P+ +  R T   + G   ++     PED G Y 
Sbjct: 526  IEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RST--CEAGVAELHIQDALPEDHGTYT 582

Query: 4048 CRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKA 4107
            C A N  G     A +                H K  +  R+ E    V P      SK 
Sbjct: 583  CLAENALGQVSCSAWVTV--------------HEK--KSSRKSEYLLPVAP------SKP 620

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH- 4166
              P     L D + V +G       +V+G+P P V+WL NGN I     +     G  H 
Sbjct: 621  TAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679

Query: 4167 FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
              I +    DTG                  L V   HD  +    + PR
Sbjct: 680  LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 19/282 (6%)

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQ 1979
            + +  +G A     L   SKE + +D +++   ++      D+  +   Q  +     P 
Sbjct: 1045 ETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTA-----PA 1099

Query: 1980 FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDI 2039
            F + +++  V EG  + L+  ++  +DP   + W  NG+ ++       + +    ++ I
Sbjct: 1100 FKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 2040 LYAYAEDTGTYMCKATNAVGEAVTTSSVKVD---AKSGLYLDTLDEQRLKKI------QE 2090
              A  ED G Y C A N  G+A  +  V VD   A        +  +R K         E
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217

Query: 2091 LEKYERPKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
             +   + KP  +  P    P  +      + ++ G+      +V       +T  W    
Sbjct: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMKFR 1275

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            ++I+     +  +      L IL    E  G Y     NKLG
Sbjct: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F   L+    + EG+ + L+ QV   +DP   I W  NG TL T   +  + +  L 
Sbjct: 1097 APAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            ++SI     +D G+Y C A N  G+A  +  + ++D
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 11/154 (7%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT-TDSGTYSCRATNKWGQAEISVK-LEC 3140
            +W   G  + A  R+ ++     ++  + G K+ T S T    A     + ++S   LE 
Sbjct: 1744 KWQKTGNAVRAIGRLSSM----AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1799

Query: 3141 VDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199
            V + K   KP F+  I+++E + +G +A F+C +    DP+  + W+ + Q +R S   +
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQ 1856

Query: 3200 -TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                + G   L I+     D  +Y C+A N  GE
Sbjct: 1857 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP F+  L +   + EG++   +  +  T  P  ++ W  NG+ ++     R+ C+ G  
Sbjct: 513  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 566

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQL----PKGMEGTI-- 3532
             L I    PED G Y C A N  G+   +A + V  K++      L    P      I  
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECR 3580
              ++ L+   G+  T+T +     PPE     +   + E+   HFE R
Sbjct: 627  QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 16/245 (6%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            +S+G  P F   +Q++  + +G+    +C V    DP   I W  NG+ ++ +  I    
Sbjct: 1092 ESQGTAPAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1148

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATIN----CYGKGGVYLESLQP-D 3255
            +     + I      D G Y C A N  G  E   + T++            ++S +P  
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208

Query: 3256 SLAKIRELESLQGAQQQ-TPSTP--SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDP 3312
            SL  +   ES    +++  P TP  +A PP+ I Q  +  K+  G+S     ++      
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQII-QFPEDQKVRAGESVELFGKVTGTQ-- 1265

Query: 3313 DLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +   W    K++      +  +      L IL   +E+ G Y  +  NKLG    + NL
Sbjct: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325

Query: 3373 KCTSK 3377
                K
Sbjct: 1326 TVVDK 1330



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 42/151 (27%), Positives = 69/151 (45%), Gaps = 9/151 (5%)

Query: 1127 AQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNP 1186
            A +S     ++ +   TS ++    E    + ++ F+E +   EE    KP F + + + 
Sbjct: 1762 AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQA-FLEAV--AEEKPHVKPYFSKTIRDL 1818

Query: 1187 PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFVALDIIHATSA 1245
              V EG     +C++E   DP   V WF + +S+     F+  YD  G  +L I      
Sbjct: 1819 EVV-EGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1875

Query: 1246 DTGEYTVRAVNHLGSAHTSA--IVRVIERSD 1274
            D  +YT +AVN LG A  +A  IV  +E  +
Sbjct: 1876 DDAKYTCKAVNSLGEATCTAELIVETMEEGE 1906



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 4078 PKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGH 4137
            P    + EK+   E   Q   E V EE K    P F      + V EG  ARF C++ G+
Sbjct: 1777 PTSPLNAEKLESEEDVSQAFLEAVAEE-KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1835

Query: 4138 PKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P P V+W  +  +I     +++ YD
Sbjct: 1836 PDPEVVWFKDDQSIRESRHFQIDYD 1860



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT--YDGMYHFD 4168
            P F+  P  + ++EG  A+F  RV G+P+P+V W  NG  I +G R+ L     G +   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4169 IPKTRQYDTGK 4179
            I    + D GK
Sbjct: 93   IHAVHEEDRGK 103



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 3/110 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS-RVKTINDFGFVI 3616
            P+F + P    + EN +  F C +  +      V WF  G P+      ++   D G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGI--PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            L +     RD+G Y+C A+N  G+ + S  LQV+    + + P   S  K
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLK 521



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 37/239 (15%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            ++   P F + +K   V E +    +C V  +  P  RI W  NG+ +      R+  + 
Sbjct: 509  VMEVAPSFSSVLKDCAVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 563

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            G   L I     ED G Y C A N  G+      +SC     +       +  ++SE L 
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQ------VSCSAWVTV----HEKKSSRKSEYL- 612

Query: 3945 QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPN 4004
             +     K T+ ++L                    Q  + L  M+ ++    +   G+P 
Sbjct: 613  -LPVAPSKPTAPIFL--------------------QGLSDLKVMDGSQVTMTVQVSGNPP 651

Query: 4005 MKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
             +V W  NG  +     F         ++    V+PED+G Y C A N  G   T+AV+
Sbjct: 652  PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 40/129 (31%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 44  FTRQMTTQVESS--GDRQPITA--GRP---GEPSPPIFEQIFKNARFAQGGNAKFEGKLR 96
           F +Q+   V S   GDR   +A   RP   GE  PP F          +G   +F  K+ 
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE-CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P V+W +   PL    + S+  +E+ G   L I  +   D G YTC   N  G+A 
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSV--SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243

Query: 157 CSVYIQPEG 165
            S  +  +G
Sbjct: 244 MSAELSIQG 252



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 54/241 (22%), Positives = 84/241 (34%), Gaps = 15/241 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  +++D + V EG  +   C+V    DP   I W  NG+   T   +    +    +
Sbjct: 1098 PAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER- 3813
            + I+     D G Y C A N  G A  + ++T          ++ P+  S      L   
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD-DAPASENTKAPEMKSRRPKSSLPPV 1213

Query: 3814 -GRISDA-------PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
             G  SDA       PK  P  + PP+ I   +   V   E V    +V   +   +   W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQ--PITCTW 1271

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             +  K +      +         L IL    E  G Y     N  G    +  ++    P
Sbjct: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331

Query: 3926 D 3926
            D
Sbjct: 1332 D 1332



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD-FSYVSLD 2834
            F   + ++   EG    F+C +E   DP  ++ WF +++ +     ++  +D     SL 
Sbjct: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I+    +D   YTCKA NS G AT +  L
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 33/104 (31%), Positives = 45/104 (43%), Gaps = 4/104 (3%)

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH-R 2157
            P+E ++    P F +   S E +KE     F C V  I  P +   WF  G  +R     
Sbjct: 404  PMEGQRDSAFPKFESKPQSQE-VKENQTVKFRCEVSGIPKPEVA--WFLEGTPVRRQEGS 460

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 D G   L +L     DSGTY C A+N  G+   + TL+V
Sbjct: 461  IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVA 2036
            P+F    ++ EV E   V     ++ +  P   V W+  G PV++       Y D G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            L +L A   D+GTY C A+NA G+   + +++V+
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVE 505



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 4/84 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY-DFGYV 4031
            P+F ++ QSQ  + E +T KF C+++  G P  +V WF  G P+  +     +Y D G  
Sbjct: 414  PKFESKPQSQ-EVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYG 4055
             +        DSG Y C A+N  G
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQG 494



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/86 (25%), Positives = 41/86 (47%)

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            + Q  AP F ++   ++V EG+ ++L  +    P   I W  +G  +     + +  +G 
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
              ++ I +A   D   Y+C A+N AG
Sbjct: 1152 LCSVSIEKALPEDRGLYKCVAKNDAG 1177



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592
            +K+ + E  S        E +    P F+ T  DL + E S+A F+C++    D    V 
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VV 1841

Query: 3593 WFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            WF + + +      +   ++ G   L I  V   D   YTCKA N  GEAT + +L V+
Sbjct: 1842 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 56/240 (23%), Positives = 92/240 (38%), Gaps = 17/240 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP     L++V + EG++   + ++   SD    + W  N K LK+      +      +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV------HSKKSIYLESQH-EGALPRLN 1689
            + I   LPED G Y C A N  G+A  S    V       + K+  ++S+  + +LP + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ--AAHFEARLI--PVGDPKLRVE 1745
              E  +  ++  A        P   MP + I+  E+Q   A     L     G   +   
Sbjct: 1215 GTESDATVKKKPAP----KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W++    I+ S  +   +      L +     E  G YT    N+LG       L V  K
Sbjct: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            E  G  P F   L  + ++ EG +   +C+V   +DP  TI W  NG+ ++       + 
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1148

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +    ++ I     ED G Y C A N  G+A  +C + V
Sbjct: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            P E    S  PKF ++ +S  V+E++ V+F C V     PK  + W+  G  +       
Sbjct: 404  PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEV--SGIPKPEVAWFLEGTPVRRQEGSI 461

Query: 3880 TVY-DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
             VY D G   L +L     DSG Y C A N  G+     T+  ++L
Sbjct: 462  EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERL 507



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 1/100 (1%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNH 320
            P   P  ++  R+ ++ EG+ A+F  ++ G P P V WFK+ Q +  S   +I      +
Sbjct: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             +L + +    D   YT  A N  G    +  L VE+  E
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLTYDGMYHFD 4168
            P F S P +  V+E +  +F C V+G PKP V W L G  +    GS       G ++  
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 4169 IPKTRQYDTG 4178
            + K R  D+G
Sbjct: 474  LLKARTRDSG 483



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 2/111 (1%)

Query: 470  KSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            +S E   Q  L  + +E+  V P F +    L V EG     + +  G P P + W KD 
Sbjct: 1787 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1846

Query: 529  VPIIPNPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              I  +   +I + + G  +L I      D A Y C A N  G     A L
Sbjct: 1847 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1897



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++ ++ EG+     C++    DP   + W  N K ++ +  I  + +    S
Sbjct: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            ++I     ED G+Y C A N  G+
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQ 1178



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 3/113 (2%)

Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHDFGYVALDIASVRA 1110
            + ++ E Q+  F  R E        V W+  G  +      I+ Y D G   L +   R 
Sbjct: 422  SQEVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKART 479

Query: 1111 EDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFV 1163
             DSG Y+  A NA G+   S ++ VE  + ++ +     + +    IE   FV
Sbjct: 480  RDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNKYS 119
           +T   P + + P F    ++   + G +      + G+P P V W R  KA   +   + 
Sbjct: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769

Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSV 159
           +  NE     +L++K++ P   G+Y    +N+ GE  C V
Sbjct: 770 VLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQV 807



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 43/192 (22%), Positives = 68/192 (35%), Gaps = 10/192 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            T+++     +   P F  ++Q    + E +    +CQ++   DP   + W  NGK L   
Sbjct: 1085 TDNEKRSESQGTAPAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTT 1141

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV------Y 4073
                   +    +++     PED G Y C A N  G  E    +     P          
Sbjct: 1142 KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEM 1201

Query: 4074 DSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCR 4133
             S+ PK         E +A+ +  P       KA  PP  +  P+   V  GE      +
Sbjct: 1202 KSRRPKSSLPPVLGTESDATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVRAGESVELFGK 1260

Query: 4134 VTGHPKPRVMWL 4145
            VTG       W+
Sbjct: 1261 VTGTQPITCTWM 1272



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+Q  ++   A+G     + ++  +P   + WT     L +  K+ +  +++    S+
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFII-LSQEGSLCSV 1155

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             I++  P D G Y C A+N  G+A CS  +
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQV 1185



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERD 2980
            ++VEG     + ++E   DP+  + W+ + + + +   F++  D  G  +L + DV   D
Sbjct: 1819 EVVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1876

Query: 2981 SGIYTCKAYNKRGEA 2995
               YTCKA N  GEA
Sbjct: 1877 DAKYTCKAVNSLGEA 1891



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE-FDYVA 1369
            P+F     + E  E   V   C +   G     V WF  G P++        YE      
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L LL     DSG Y+C A+N  G+   S  L+V
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            +D  K      T P F  +++   V E + +  +C+V    DP   I W  NGK L +  
Sbjct: 1085 TDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTK 1142

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
                  +    S+ I     ED G Y C A ND G+
Sbjct: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIV--NGSRYKL 4159
            V+E      P F+S P +VT   G+     C + G P P V WL +G  +    G    L
Sbjct: 712  VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771

Query: 4160 TYDGMYHFDIPKTRQYDTGKIEVI 4183
              + ++   + K + +  G+ E++
Sbjct: 772  QNEDVFTLVLKKVQPWHAGQYEIL 795



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/92 (22%), Positives = 41/92 (44%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F +K+Q   V E ++   + +   +P   I W      +K +    +    +   + I
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
             +   ED  ++  VA+N  G A+CS  + V++
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 3013 TQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASL 3072
            T  P      EK+++ ED  +       ++     P F+   +D+ ++ EG  A ++  +
Sbjct: 1774 TGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKI 1832

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
                D  +V  WF + ++I  S   +  Y   G   L I      D   Y+C+A N  G+
Sbjct: 1833 EGYPDPEVV--WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1890

Query: 3132 AEISVKL--ECVDKSKGQ 3147
            A  + +L  E +++ +G+
Sbjct: 1891 ATCTAELIVETMEEGEGE 1908



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 14/127 (11%)

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPK----FITQIQDVTKLVEGQSAHFEARLVPV 3309
            P S     +LES +   Q      + E P     F   I+D+ ++VEG +A F+ ++   
Sbjct: 1777 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGY 1835

Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHD----FGIVILDILYCYEENSGEYECVATNKLGR 3365
             DP+  V WF + + +     ++  +D      ++I D+  C ++++ +Y C A N LG 
Sbjct: 1836 PDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV--CGDDDA-KYTCKAVNSLGE 1890

Query: 3366 DSTKANL 3372
             +  A L
Sbjct: 1891 ATCTAEL 1897



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQSGHRYRTSNDFGFAALDILTVYGED 1913
            ++ E Q+  + C +   P P   V W+  G  V +         D G   L +L     D
Sbjct: 424  EVKENQTVKFRCEVSGIPKPE--VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQ 1937
            SG Y+C A N  GQ   S  L V+
Sbjct: 482  SGTYSCTASNAQGQVSCSWTLQVE 505



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 4/94 (4%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYV 967
            P+F++  + Q  +KE     F  R E  G     V W  +G PV      I  + + G  
Sbjct: 414  PKFESKPQSQ-EVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L +      D+G Y+C A NA GQ + S  L +
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GF 2565
            KP F++ +    E+ EG  A ++ ++    DP +   W+ +   ++    F+  +D  G 
Sbjct: 1808 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEV--VWFKDDQSIRESRHFQIDYDEDGN 1864

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I+ V  +D   Y CKA+N  G
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLG 1889



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 3/63 (4%)

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            ++  SW +  E++     A   P F S+     V EG+     C V G P PR+ WLLNG
Sbjct: 495  QVSCSWTLQVERLAVMEVA---PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551

Query: 4149 NTI 4151
              I
Sbjct: 552  QPI 554



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 2232 IEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL-QSAA 2289
            + V+EP   + P F+++ R  T    G++    C +    DP   + +  +GKAL +   
Sbjct: 710  LTVQEPHDGTQPWFISKPRSVTASL-GQSVLISCAI--AGDPFPTVHWLRDGKALCKDTG 766

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS-MTVTAKGSIISESQRPE 2348
             F +  +    +L ++   P  AG+Y +   N +G C+  +S M   +    +   + P 
Sbjct: 767  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 826

Query: 2349 GLEKI 2353
              E +
Sbjct: 827  SCEDL 831



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 4/85 (4%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWF-RNEKLIEDSSRITKTHDFGYV 2434
            P F    Q+   ++E QT  F C +   G P  +V WF     +      I    D G  
Sbjct: 414  PKFESKPQS-QEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
             + +   R  D G Y C ASN  G+
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQGQ 495



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 5/109 (4%)

Query: 628 GEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTS 687
           G+ D  +P  +F    +S    E   + F  R E  G P  ++ W   G  +        
Sbjct: 407 GQRDSAFP--KFESKPQSQEVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462

Query: 688 IFR-FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
           ++   G   L +L    +DSG Y+C A +A G       L V   A +E
Sbjct: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME 511



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 13/120 (10%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL--PSGHRYR 3879
            +EP   T P FI++ +S T    + V   C +    DP   + W R+GK L   +GH + 
Sbjct: 713  QEPHDGTQPWFISKPRSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGH-FE 769

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
             + +    +L +  V    +G+Y     N  GE        C     ++LQN   R + R
Sbjct: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--------CSCQVSLMLQNSSARALPR 821



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTLNDFGFIALDIDYIYARD 3764
            +V E   V F C V   G P   + WF  G P       +    D G   L +     RD
Sbjct: 424  EVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481

Query: 3765 AGEYTCRATNKWGSAT 3780
            +G Y+C A+N  G  +
Sbjct: 482  SGTYSCTASNAQGQVS 497



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 33/88 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P+ ++      VR GE V L  +  GT     TW K    I  +  +++      S L I
Sbjct: 1238 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A+      Y    +N  GS   +  L
Sbjct: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNL 1325



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 1738 GDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            GDP   V WLR+G  + + +     + +     L +K V P  +G Y     N +GE   
Sbjct: 746  GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 805

Query: 1797 SSTLFVQSKASLQLESQHESA 1817
              +L +Q+ ++  L    E A
Sbjct: 806  QVSLMLQNSSARALPRGREPA 826



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
            +E+RSE    +   P F Q L     + EG+    + +V    DP     W +NG  LK 
Sbjct: 1087 NEKRSES---QGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT 1140

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                  + +    ++ I   +  D GLY C A N AG
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAG 1177


>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
            isoform 3A protein.
          Length = 1862

 Score =  167 bits (407), Expect = 7e-40
 Identities = 116/431 (26%), Positives = 185/431 (42%), Gaps = 13/431 (3%)

Query: 4389 EIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN 4448
            ++  KA  +   +EG  + S  P F  K Q   V E++  +F  E  G P P + W+ E 
Sbjct: 393  DVVSKAANRRIPMEGQ-RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEG 451

Query: 4449 FPIKNSP-DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
             P++      +++  +    L + +    DS  ++  A N  G   CS  L VE      
Sbjct: 452  TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME 511

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567
                V PSF+   ++  V  GQ   L   V GT    + WL NG+ +Q   R+    E G
Sbjct: 512  ----VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTC--EAG 564

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK---PQTKAANAPPE 4624
               L I +A P+D G Y C+A N+ G+  C A   V    +  K +   P   +    P 
Sbjct: 565  VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
             ++ L D  V +G  +  + ++ G P P V W      I+ S+ F   +   +++L I E
Sbjct: 625  FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQE 684

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
             FPED G Y C A+NSAG V   A L V +P        ++  R +    GQ       I
Sbjct: 685  VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744

Query: 4745 TSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                 PT+ WLR+G AL  +T  F+++   +   L++        G +        G+  
Sbjct: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804

Query: 4804 TSAKLVVKSKT 4814
                L++++ +
Sbjct: 805  CQVSLMLQNSS 815



 Score =  109 bits (262), Expect = 2e-22
 Identities = 80/334 (23%), Positives = 136/334 (40%), Gaps = 19/334 (5%)

Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
           G+     + +++R       P  +   ++  + EG D   Q  + G P PR+TW  NGQ 
Sbjct: 494 GQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553

Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
           +  +             L +++    D G YT LAEN  G +  S ++ V     S    
Sbjct: 554 IQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS---- 606

Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           ++S+Y+                K  AP F++   D  V +G       +V+G P PEV W
Sbjct: 607 RKSEYLLPVAP----------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             N  +I++  +          H+L I  V   D+G  TC A N +GE   Q  L V E 
Sbjct: 657 LHNGNEIQESEDFHF-EQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715

Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGG 544
                P F+ +  ++    G+ V+++    G P P + W +DG  +  +     +  +  
Sbjct: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775

Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             TL + + +   A  Y+   +N  G  + +  L
Sbjct: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809



 Score =  107 bits (258), Expect = 7e-22
 Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 14/235 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-G 3476
            +AP F +P  N+  ++EG  A FE R+    +P  +V W+ NG+ + +G RF   C   G
Sbjct: 31   EAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRG 87

Query: 3477 FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIA 3536
               L I   + ED G+Y C A N  G    T  + V+G        QL + +   + K  
Sbjct: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPV---VSKTL 140

Query: 3537 ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
                 +  V+T  P      PP+F T    +++ E     F C++        +V W   
Sbjct: 141  GDRFSASAVET-RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
              PL   +RV      G  +LEI GV Q D G+YTC   N  G+A++S +L ++G
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score =  104 bits (250), Expect = 7e-21
 Identities = 88/328 (26%), Positives = 132/328 (40%), Gaps = 46/328 (14%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEIITTHNHTTLR 324
           PK   KP++ +++E    +F+ ++SG P+P V WF  G  +       E+        L 
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +   +  DSG Y+  A N  G +  S  L VE                         R+ 
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVE-------------------------RLA 508

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
           + E  +AP F  V +D  V EG+     C V G P P +TW +N + I+  Y       E
Sbjct: 509 VME--VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTC--E 562

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE--------------QVVA 490
           +G   L I +    D G  TC+A N  G+ +    + V EK+              +  A
Sbjct: 563 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P F++  S L V +G  V +  +  G P P + W  +G  I  + +      G   +L I
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 682

Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARL 578
                 D   Y C A N AG   T+A L
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score =  102 bits (244), Expect = 4e-20
 Identities = 76/245 (31%), Positives = 112/245 (45%), Gaps = 10/245 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDF 1765
            +T+AP F +P +++ + E   A FE R+   G P+ +V W RNG PI +  R L      
Sbjct: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G  +L +  V+ ED G YTC A N  G    +  L V+   + QL     S  + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS--KTLGDRF 144

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             +S  + R  +       P+F T+L G   + EGQ   + C+I   P P  +V W     
Sbjct: 145  SASAVETRPSIWGEC--PPKFATKL-GRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNV 199

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
             LQ   R   S   G   L+I  V  +D G YTC  +N  G+A  S  L++Q  +S  R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 1946 SQHES 1950
               E+
Sbjct: 260  FVRET 264



 Score =  100 bits (240), Expect = 1e-19
 Identities = 68/246 (27%), Positives = 114/246 (46%), Gaps = 5/246 (2%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           +   ++ ++ + +      S+     P     PRN  ++EGA A+F+ ++ G P P+VTW
Sbjct: 7   VASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTW 66

Query: 300 FKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-S 357
            +NGQ + +  +  +      T +L +    + D G YT  A N +G    +  L VE S
Sbjct: 67  HRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126

Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
             +   Q   S+ + D       E          P+F        V EG+M RF C++TG
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNE-SGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
           RP P+VTW   +  ++   + ++ V+E +G   L I  V   D GV TC+  N SG+ + 
Sbjct: 187 RPQPQVTWLKGNVPLQP--SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244

Query: 477 QCRLNV 482
              L++
Sbjct: 245 SAELSI 250



 Score =  100 bits (240), Expect = 1e-19
 Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 8/219 (3%)

Query: 4404 PVKPSKP--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            PV PSKP  PIF + +   +V +  Q    V+  G P P + W      I+ S DF    
Sbjct: 614  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
              T+  L I++VF ED+  +   A N  G  +  A L V+E    G      P F    +
Sbjct: 674  RGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH-DG----TQPWFISKPR 728

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQD 4580
            +V  + GQ V +   + G     V+WL++GK +  D  + ++L+ +  +TL++ +  P  
Sbjct: 729  SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +G+YE +  N  GE  C    ++   + +  P+ +  A+
Sbjct: 789  AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPAS 827



 Score =  100 bits (239), Expect = 1e-19
 Identities = 107/361 (29%), Positives = 152/361 (42%), Gaps = 62/361 (17%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH-DFGYV 1502
            P+F ++P+S E V E Q V F C++  +     +V WF  G PV        ++ D G  
Sbjct: 414  PKFESKPQSQE-VKENQTVKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L ++     DSG Y+C A N  G  +VSC  T +              +E++ V+E   
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQG--QVSCSWTLQ--------------VERLAVME--- 511

Query: 1563 KYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKS 1622
                          AP  ++ LK+  + EGQ   F  +         ++ W  N +P++ 
Sbjct: 512  -------------VAPSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQY 556

Query: 1623 GSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHE 1682
                 E    G   L I   LPED GTYTC A NALG+   S    VH KKS     + E
Sbjct: 557  ARSTCEA---GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS---SRKSE 610

Query: 1683 GALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL 1742
              LP        SK             AP+F   + D++V +        ++   G+P  
Sbjct: 611  YLLP-----VAPSK-----------PTAPIFLQGLSDLKVMDGSQVTMTVQV--SGNPPP 652

Query: 1743 RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             V WL NG  I+ S            +L ++ V PED+GTYTC A N  GE  T + L V
Sbjct: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712

Query: 1803 Q 1803
            Q
Sbjct: 713  Q 713



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 19/225 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P+F L  +N+ +  G   + + +V G     V W +NG+ +    R  +     GT++L+
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP---------------QTK 4617
            I   + +D GKY C A N +G  +   E  V     K   +P               +T+
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4618 AA---NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             +     PP+    L   +V EGQ   FSCKI G+P P V W KG+  ++PS    +S  
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
                 L I     +D G Y C+  N +G+ +++A+L +   D A+
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 167/703 (23%), Positives = 277/703 (39%), Gaps = 94/703 (13%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            FI    N+  KEG    FE  V    +P  ++ W  N +P+ SG R+          SL 
Sbjct: 35   FILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I   +EED G YTC+ATN  G+   +  L   G     F  Q  Q        ++   + 
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSAS- 147

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
             A   RPS+   E P P++   +     + EGQ+     ++  +  P  ++ W      L
Sbjct: 148  -AVETRPSIWG-ECP-PKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPL 201

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD----NLI 3010
            +  +R  ++   G   L++  V + D G+YTC   N  G+A  S+ +     D    + +
Sbjct: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV 261

Query: 3011 ERTQHPKGTEGLE---------KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDIS 3061
              T+        E         K+ +LE + + +    P    G PP             
Sbjct: 262  RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRG-GSPP--WAANSQPQPPR 318

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK-----TT 3116
            E ++   + S   T  Q+ V++   +  T++A+       A G+ VL   G +       
Sbjct: 319  ESKLESCKDS-PRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP 377

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQK----PRFTTHIQNIEGLKDGQSAHFECT 3172
               T+  R      Q  +S         +GQ+    P+F +  Q+ E +K+ Q+  F C 
Sbjct: 378  RPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE-VKENQTVKFRCE 436

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHST-RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            V  +  P+  + W+  G P+R     I+   D G   L +   +  DSG Y C A N  G
Sbjct: 437  VSGIPKPE--VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494

Query: 3232 EDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDV 3291
            +      ++C         +LQ + LA            +  PS        F + ++D 
Sbjct: 495  Q------VSCSW-------TLQVERLA----------VMEVAPS--------FSSVLKDC 523

Query: 3292 TKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEEN 3351
              ++EGQ   F  +      P  ++ W  NG+ + +    R+  + G+  L I     E+
Sbjct: 524  A-VIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPED 577

Query: 3352 SGEYECVATNKLGRDSTKA----NLKCTSKENLILDSQLPRGMEG-----GLEKLQTLED 3402
             G Y C+A N LG+ S  A    + K +S+++  L    P          GL  L+ ++ 
Sbjct: 578  HGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDG 637

Query: 3403 SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLT 3445
            S V    T   +  G  P   + L N   ++E E+ HFE R T
Sbjct: 638  SQV----TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 18/246 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-VKTINDFGFVI 3616
            P F   P +L + E ++A FE R+    +   +V W  NG+P+ +G R +      G   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V++ D G YTC+ATN  G   V+ +L V+G        QL     S T   +   
Sbjct: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSA 146

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
              +  R  I  E     PP+F  ++   + V EG    F C++   G P  ++ W     
Sbjct: 147  SAVETRPSIWGEC----PPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNV 199

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC----SAKRD 3792
            P    +RV      G   L+I  +   D G YTC   N  G A+ +A+++     SA R 
Sbjct: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259

Query: 3793 IVLESQ 3798
             V E++
Sbjct: 260  FVRETK 265



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 64/224 (28%), Positives = 96/224 (42%), Gaps = 25/224 (11%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F   +K+  V EG    L+ ++     P  R+ W  NG+P+Q     ++T + G   L
Sbjct: 514  PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 568

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             I  A  ED GTY C A NA+G+   ++ V V  K                +   K E  
Sbjct: 569  HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK----------------KSSRKSEYL 612

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
             P+   +P   P+FL  L+   +LK  D +     V+   +P   + W HNG +I+    
Sbjct: 613  LPVAPSKP-TAPIFLQGLS---DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +         +L I   + ED+GTY C+A N  GE      L V
Sbjct: 669  FHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 16/225 (7%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGFIALDIDYIYA 3762
            N+ + EG    F+ RV   G P  ++ W  NG+P  +G R +      G  +L I  ++ 
Sbjct: 41   NLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS-DAPK 3821
             D G+YTC ATN  G+   T ++T           QL Q +  + + +    R S  A +
Sbjct: 99   EDRGKYTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGD----RFSASAVE 150

Query: 3822 EEPIV--STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              P +    PPKF T++    V+E +  RF C++  +  P  ++ W +    L    R  
Sbjct: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVS 208

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
                 G   L+I  V  +D G Y C  VN  G+    A +S + L
Sbjct: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 18/242 (7%)

Query: 2899 RRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS 2958
            R  S+P TE   P +I+P      + EG     EG+V  +  P+ ++ W+ NG+ +  G 
Sbjct: 23   RVDSMPLTE--APAFILP-PRNLCIKEGATAKFEGRV--RGYPEPQVTWHRNGQPITSGG 77

Query: 2959 RFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK 3017
            RF L     G  +L +  V+E D G YTC+A N  G      TV  T + +  ++   P 
Sbjct: 78   RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPV 135

Query: 3018 GTEGLEKIQNLEDSLRKEPGQQPDDDTGR-PPEFTTVFKDIVDISEGQIAHYEASLIPTG 3076
             ++       L D       +      G  PP+F T    +V + EGQ+  +   +  TG
Sbjct: 136  VSK------TLGDRFSASAVETRPSIWGECPPKFATKLGRVV-VKEGQMGRFSCKI--TG 186

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
                 + W      ++ S R+      GM VLEI G    D G Y+C   N  G+A +S 
Sbjct: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246

Query: 3137 KL 3138
            +L
Sbjct: 247  EL 248



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 62/249 (24%), Positives = 111/249 (44%), Gaps = 12/249 (4%)

Query: 617 HVERARPYIPPGEEDRV--YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLK 674
           H+ +    + P   D +     P FI+P +++   EG    FE R+   G P  ++ W +
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHR 68

Query: 675 NGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
           NGQ I +  RF       G  SL + +++ +D G+YTC A + +G  +    + +T   +
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV--TVELTVEGS 126

Query: 734 IERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQ 793
             +    P   + +      S  + + SI  +    P+F   L  +  ++EG+   F  +
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGECP--PKFATKLGRV-VVKEGQMGRFSCK 183

Query: 794 LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           +T    P  +V W K   P+  S+R++     G   L I  +  +D G YT   VN  G+
Sbjct: 184 IT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241

Query: 854 AISTASIRV 862
           A  +A + +
Sbjct: 242 ASMSAELSI 250



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 65/228 (28%), Positives = 99/228 (43%), Gaps = 14/228 (6%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            +T  P F+  P+++  + EG    FE ++    +   +V W +NGQP+T G RF      
Sbjct: 29   LTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGI 85

Query: 1500 -GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI-QV 1557
             G  +L I  +  ED G YTC A N  G  +V+  LT         S   + G   + + 
Sbjct: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG------SFAKQLGQPVVSKT 139

Query: 1558 LEDRSKYHRTDMVDEVTTQAPI-CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            L DR      +    +  + P    T L  V +KEGQ   F  ++        +V W   
Sbjct: 140  LGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKG 197

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            N PL+  +R + +   G   L+I     +D G YTC  +N  G+A  S
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 65/244 (26%), Positives = 106/244 (43%), Gaps = 15/244 (6%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF- 964
            T+ P F  P ++ + IKEG  A FE R+   G    +V W ++G+P+ +  R        
Sbjct: 30   TEAPAFILPPRN-LCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIR 86

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
            G  +L I +V   D G YTC A N  G    +  LT+  +     +   P   + +    
Sbjct: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRF 144

Query: 1025 DASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEWYFN 1082
             AS  +  T   +     P+F   L G   + EGQ   F  ++   PQ  +T    W   
Sbjct: 145  SAS--AVETRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVT----WLKG 197

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
               +  + R+      G   L+I  V  +D GVYT +  N +G+A +SA ++++   S +
Sbjct: 198  NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257

Query: 1143 TSSI 1146
             S +
Sbjct: 258  RSFV 261



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 80/317 (25%), Positives = 135/317 (42%), Gaps = 33/317 (10%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA-FGMVVLEILGTKTTD 3117
            ++ E Q   +   +  +G     + WF  G  +        VY   G   L +L  +T D
Sbjct: 424  EVKENQTVKFRCEV--SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            SGTYSC A+N  GQ   S  L+    +  +  P F++ +++   + +GQ    +C+V   
Sbjct: 482  SGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDC-AVIEGQDFVLQCSVRGT 540

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P  +I W  NGQP++++   ++  + G   L I      D G Y C A N  G+    
Sbjct: 541  PVP--RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCS 595

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +  + K      S + + L  +             PS P+A  P F+  + D+ K+++
Sbjct: 596  AWVTVHEK----KSSRKSEYLLPV------------APSKPTA--PIFLQGLSDL-KVMD 636

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV-ILDILYCYEENSGEY 3355
            G       ++    +P  +V W +NG ++     +  F   G    L I   + E++G Y
Sbjct: 637  GSQVTMTVQV--SGNPPPEVIWLHNGNEIQESEDFH-FEQRGTQHSLWIQEVFPEDTGTY 693

Query: 3356 ECVATNKLGRDSTKANL 3372
             C A N  G   T+A L
Sbjct: 694  TCEAWNSAGEVRTQAVL 710



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 69/260 (26%), Positives = 114/260 (43%), Gaps = 36/260 (13%)

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            EKR + +G    P+F    Q+V+V  G+ + L  +V+   P  + W  NGK ++   +  
Sbjct: 1088 EKRSESQG--TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFI 1144

Query: 4562 ILEEDGTYTLLILE-AYPQDSGKYECVAINSAGEARCDAECVV-SLPATKDKPKPQTK-- 4617
            IL ++G+   + +E A  +D G Y+CVA N AG+A C  +  V   PA+++   P+ K  
Sbjct: 1145 ILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204

Query: 4618 ----------------------AANAPP------EIIEPLKDKIVAEGQAIEFSCKIVGK 4649
                                  A   PP      +II+  +D+ V  G+++E   K+ G 
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
               T  W K  K I+ S++ ++  + +   L I  A  E  G Y  +  N  G       
Sbjct: 1265 QPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1324

Query: 4710 LKVT-QPDQADNLPALTPLR 4728
            L V  +PD     P  + +R
Sbjct: 1325 LTVVDKPDPPAGTPCASDIR 1344



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 11/215 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGI 2714
            EG     E +V    +P  ++ W +NG  +T+G R        G  +L I+++  +D G 
Sbjct: 46   EGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2715 YTCKATNLLGEAVSTASIKIEDRHWL-LGESLHPDSL-DRIGALXXXXXXXXXXXXXXXX 2772
            YTC+ATN  G    T  + +E      LG+ +   +L DR  A                 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA----SAVETRPSIWGEC 159

Query: 2773 XXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS 2832
               F + L  +V KEG    F C +     P  ++ W   N PL    R   +       
Sbjct: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQV 217

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            L+I    ++D G+YTC   N  G A+ S  L   G
Sbjct: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 36/93 (38%), Positives = 53/93 (56%)

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            E +   +  + P F K  +D +V EG   RFDC++ G P PEV WF +D+ IR+  + +I
Sbjct: 1746 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1805

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
              +E GN +L+I++V   D    TC A N  GE
Sbjct: 1806 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1838



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 12/194 (6%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYVAMNFGWVYPEDSGE 4045
            E  T KFE ++   G P  +V W  NG+P+    RF       G  ++    V+ ED G+
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 4046 YLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEES 4105
            Y C ATN  G  +    +   G     +  QL + + S        AS   T   +  E 
Sbjct: 104  YTCEATNGSGARQVTVELTVEGS----FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE- 158

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGM 4164
               CPP F +    V V+EG+  RF C++TG P+P+V WL     +   +R  ++  +GM
Sbjct: 159  ---CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGM 215

Query: 4165 YHFDIPKTRQYDTG 4178
               +I    Q D G
Sbjct: 216  QVLEIHGVNQDDVG 229



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 14/252 (5%)

Query: 1970 DDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            D   + E P F  P +N  + EG     E  +    +P  +V W+ NG+P+  G RF   
Sbjct: 25   DSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLD 82

Query: 2030 YDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYL-DTLDEQRLKK 2087
                G  +L I   + ED G Y C+ATN  G    T  + V+      L   +  + L  
Sbjct: 83   CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                   E    I  E P   P F T L  +  +KEG    F C++     P +T  W  
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKITGRPQPQVT--WLK 196

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG---- 2203
                ++   R   +   G   L+I     +D G Y C   N  G+A  +  L + G    
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256

Query: 2204 HRNIILDTQHPN 2215
            +R+ + +T+  N
Sbjct: 257  NRSFVRETKATN 268



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 74/305 (24%), Positives = 117/305 (38%), Gaps = 21/305 (6%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P FE   ++    +    KF  ++ G P P V+W  +  P V   + S+   E  G   L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTP-VRRQEGSIEVYEDAGSHYL 472

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            + +    D G Y+CTA N  G+  CS  +Q E               +  +  +E + +
Sbjct: 473 CLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCA-VIEGQDF 531

Query: 192 GTQGYT--TEQSRQT-----QKVAYTNGTDHSSTDDFKV------DTFEYRLLREVSFRE 238
             Q     T   R T     Q + Y   T  +   +  +      D   Y  L E +  +
Sbjct: 532 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591

Query: 239 SITKRYVGESDVQISTEIDRSLGPVSP-----PKIAQKPRNSKLQEGADAQFQVQLSGNP 293
                +V   + + S + +  L PV+P     P   Q   + K+ +G+     VQ+SGNP
Sbjct: 592 VSCSAWVTVHEKKSSRKSEYLL-PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
            P V W  NG  +  S            +L ++     D+G YT  A N  G + T   L
Sbjct: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710

Query: 354 AVESP 358
            V+ P
Sbjct: 711 TVQEP 715



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 69/232 (29%), Positives = 101/232 (43%), Gaps = 27/232 (11%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V+  AP F+  +KD  V E Q   F  +    G P  R+ WL NG PI+ + R T   + 
Sbjct: 509  VMEVAPSFSSVLKDCAVIEGQ--DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EA 563

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            G   L+++   PED GTYTC A N LG+   S+ + V  K S                  
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS------------------ 605

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             S + +    V  +   AP F+  L+   K+ +G       ++   P P   V W  NG 
Sbjct: 606  -SRKSEYLLPVAPSKPTAPIFLQGLS-DLKVMDGSQVTMTVQVSGNPPP--EVIWLHNGN 661

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             +Q    +         +L I  V+ ED+G YTC+A N+ G+  +   L VQ
Sbjct: 662  EIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 61/225 (27%), Positives = 102/225 (45%), Gaps = 13/225 (5%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P    P F+   R    + EG TA FE +V    +P  ++ ++ NG+ + S  RF +   
Sbjct: 28   PLTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCG 84

Query: 2297 F-GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRE 2355
              G  SL I     ED G+Y+ +A N  G     +++ +T +GS   +  +P   + + +
Sbjct: 85   IRGTFSLVIHAVHEEDRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGD 142

Query: 2356 LESAEPFK-RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
              SA   + RP I        P F   L  +  ++EGQ   F C++   G P  +V W +
Sbjct: 143  RFSASAVETRPSIWGECP---PKFATKLGRVV-VKEGQMGRFSCKI--TGRPQPQVTWLK 196

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                ++ S+R++ +   G   + I  V  +D GVY C   N  G+
Sbjct: 197  GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 26/240 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++ P F    +   + E   A+FE    G P P + W+R   PI +   F +      + 
Sbjct: 30   TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG----------------- 4509
             L+I  V  ED   +   A N  G  + +  L VE    +  G                 
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149

Query: 4510 -------GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                   G  PP F      V V  GQ+ R   K+TG     V WLK    +QP  R  +
Sbjct: 150  ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE-CVVSLPATKDKPKPQTKAANA 4621
             E++G   L I      D G Y C+ +N +G+A   AE  +  L +       +TKA N+
Sbjct: 210  SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 67/227 (29%), Positives = 97/227 (42%), Gaps = 27/227 (11%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F + L     + EGQ    +C +   P P  R+ W  NG+ +Q     R++ + G A
Sbjct: 513  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 566

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
             L I     ED G YTC A N LGQ   S  + V  K+S            K +YL   +
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----------SRKSEYLLPVA 616

Query: 1963 RYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ 2022
              K            P F + + + +V +G  V +  T+    +P   V W  NG  +Q+
Sbjct: 617  PSKPTA---------PIFLQGLSDLKVMDGSQVTM--TVQVSGNPPPEVIWLHNGNEIQE 665

Query: 2023 GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
               F         +L I   + EDTGTY C+A N+ GE  T + + V
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 109/491 (22%), Positives = 182/491 (37%), Gaps = 27/491 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+ P  N   + EG     E R+   G P  +V W  NG+ +T G RF          
Sbjct: 33   PAFILPPRNLC-IKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89

Query: 1237 LDIIHAT-SADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
              +IHA    D G+YT  A N  G+   + +   +E S      Q  Q +    L +  +
Sbjct: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVT-VELTVEGSFA---KQLGQPVVSKTLGDRFS 145

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
                + R  I     P+F+  L  +   EG      C++   G    +V W     P++ 
Sbjct: 146  ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQP 203

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              R   + +     L++  V  +D GVYTC   N  G+A  S  L +       L+S + 
Sbjct: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG-----LDSANR 258

Query: 1416 SGLEKIQYLEDTSRYKKTDIID-ESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            S + + +      R + T++I  ES         + K+  +   G    +    +P    
Sbjct: 259  SFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
              K+E  K+  P T      P+      ++ +     +         V     +E     
Sbjct: 319  ESKLESCKD-SPRTAPQ--TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA 375

Query: 1535 TCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
              R  T   R    + GL    V+  ++   R  M  +  +  P   +  ++ E+KE Q 
Sbjct: 376  PPRPATFPTR----QPGLGSQDVV-SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET-NNFGFVALDIMSCLPEDSGTYTCR 1653
              F   +  +     +V W+    P++      E   + G   L ++     DSGTY+C 
Sbjct: 431  VKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488

Query: 1654 AINALGEAVTS 1664
            A NA G+   S
Sbjct: 489  ASNAQGQVSCS 499



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 56/224 (25%), Positives = 98/224 (43%), Gaps = 10/224 (4%)

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
            + + D  C      T D  K ++++    P   + L+D  VAEG+ +   C++   P  T
Sbjct: 1070 DVKNDVNCKRGHAGTTDNEK-RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W    K +K +K+  +S+     ++ I +A  ED G YKCVA N AG+   + ++ V 
Sbjct: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVD 1188

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQ--ITSKIKPTIQWLREGALIPET---PDFQ 4768
                ++N  A   ++        P    T+   T K KP  +   + A+ P+    P+ Q
Sbjct: 1189 DAPASENTKA-PEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +  G  +V L G      T   TC       Q++ S  + V++
Sbjct: 1248 KVRAG-ESVELFGKV--TGTQPITCTWMKFRKQIQDSEHIKVEN 1288



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 71/270 (26%), Positives = 105/270 (38%), Gaps = 23/270 (8%)

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G V  VA +   +T+     + ++   +  AP F+     L ++EG       R  G P 
Sbjct: 2   GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 520 PRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P++TW ++G PI       +     G  +L I      D   Y C A N +G     AR 
Sbjct: 62  PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG-----ARQ 116

Query: 579 YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQ 638
                       K+L  P  +K                 VE  RP I  GE      PP+
Sbjct: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSASA-------VE-TRPSI-WGE-----CPPK 162

Query: 639 FIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDM 698
           F   L  V   EG    F  +I   G P  ++ WLK    ++ S+R +   + G   L++
Sbjct: 163 FATKLGRVVVKEGQMGRFSCKI--TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220

Query: 699 LSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +N  D G YTC  V+ +G A   A L +
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 69/245 (28%), Positives = 100/245 (40%), Gaps = 29/245 (11%)

Query: 1298 TKQVREDITVMQ-APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            T QV E + VM+ AP FS  L +   +EG +  L+C ++  G    R+ W  NG+PI+  
Sbjct: 501  TLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA 557

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
               R   E     L +    PED G YTC A N LG+   S  + V  KK          
Sbjct: 558  ---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK---------- 604

Query: 1417 GLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL 1476
               K +YL   +  K T          P F+     ++ V++G  V    ++    +   
Sbjct: 605  SSRKSEYLLPVAPSKPT---------APIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPP 652

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            +V W  NG  +     F         +L I ++  ED+G YTC A N  G       LT 
Sbjct: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712

Query: 1537 RSTTD 1541
            +   D
Sbjct: 713  QEPHD 717



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 34/88 (38%), Positives = 48/88 (54%), Gaps = 1/88 (1%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLR 4681
            P   + ++D  V EG A  F CKI G P P V W+K D+ I+ S++FQ+    D   +L 
Sbjct: 1757 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1816

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            IS+   +D+  Y C A NS G  T  A+
Sbjct: 1817 ISDVCGDDDAKYTCKAVNSLGEATCTAE 1844



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 64/250 (25%), Positives = 102/250 (40%), Gaps = 11/250 (4%)

Query: 3125 ATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKI 3183
            A++   +  +SV    VD     + P F    +N+  +K+G +A FE  V    +P  ++
Sbjct: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVRGYPEP--QV 64

Query: 3184 EWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             W+ NGQP+    R        G   L I      D G+Y C A N  G    + T+   
Sbjct: 65   TWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELT 122

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +G    +  QP     + +  S    + + PS     PPKF T++  V  + EGQ   F
Sbjct: 123  VEGSFAKQLGQPVVSKTLGDRFSASAVETR-PSIWGECPPKFATKLGRVV-VKEGQMGRF 180

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
              ++     P  +V W      L    R       G+ +L+I    +++ G Y C+  N 
Sbjct: 181  SCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238

Query: 3363 LGRDSTKANL 3372
             G+ S  A L
Sbjct: 239  SGKASMSAEL 248



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 1/93 (1%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYT 4570
            V P F+ T +++ V  G   R D K+ G    +V W K+ + ++     +I  +EDG  +
Sbjct: 1755 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1814

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            L+I +    D  KY C A+NS GEA C AE +V
Sbjct: 1815 LIISDVCGDDDAKYTCKAVNSLGEATCTAEHIV 1847



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/243 (23%), Positives = 99/243 (40%), Gaps = 35/243 (14%)

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-- 425
           S +I+ T       R++      AP F+   ++  + EG   +F+ RV G P P+VTW  
Sbjct: 9   SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68

Query: 426 ----------FINDRQIRDDYN---HKILVNESGNHALMITN--------VTLSDSG--- 461
                     F+ D  IR  ++   H +   + G +    TN        V L+  G   
Sbjct: 69  NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128

Query: 462 ------VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
                 VV+    ++   +A + R ++  +     PKF  +   + V+EG+    + +  
Sbjct: 129 KQLGQPVVSKTLGDRFSASAVETRPSIWGE---CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           G P P++TW K  VP+ P+  + +    G   L+I      D   Y C   N +G  +  
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245

Query: 576 ARL 578
           A L
Sbjct: 246 AEL 248



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 58/217 (26%), Positives = 91/217 (41%), Gaps = 14/217 (6%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGL 2580
            EG  A +E RV   G P  +  W+ NG  +  G RF       G  +L I++V   D G 
Sbjct: 46   EGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103

Query: 2581 YMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQI--QLKEAAMNKVPEMFVDTGV 2638
            Y C+A N +G                  Q  +P   + +  +   +A+   P ++ +   
Sbjct: 104  YTCEATNGSGARQVTVELTVEGSFA--KQLGQPVVSKTLGDRFSASAVETRPSIWGEC-- 159

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
               P F T L     + EGQ      ++  R  P  ++ W K  V L   AR+  +   G
Sbjct: 160  --PPKFATKLGRV-VVKEGQMGRFSCKITGRPQP--QVTWLKGNVPLQPSARVSVSEKNG 214

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            +  L I+ +  DD G+YTC   N  G+A  +A + I+
Sbjct: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 6/119 (5%)

Query: 1415 PSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            P   EK++  ED S+     + +E   +KP F    + +E V+EG    F+CK+E   D 
Sbjct: 1728 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1786

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
              +V WFK+ Q +     F+  +D  G  +L I D+  +D   YTC+AVN +G  E +C
Sbjct: 1787 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATC 1841



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 6/100 (6%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            + EE+P  +P F   +  LE + EG  A F+C++E   DP +   WF + Q IR    ++
Sbjct: 1748 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQ 1804

Query: 2160 TTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
              +D  G  +L I     +D   Y CKA N LGEA  TCT
Sbjct: 1805 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCT 1842



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 53/219 (24%), Positives = 93/219 (42%), Gaps = 30/219 (13%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLR 4681
            P  I P ++  + EG   +F  ++ G P P V W++ G  +    ++         ++L 
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4682 ISEAFPEDEGDYKCVAYNSAG--RVTVAAKLK------VTQPDQADNL------------ 4721
            I     ED G Y C A N +G  +VTV   ++      + QP  +  L            
Sbjct: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152

Query: 4722 PAL---------TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
            P++         T L  +VV EGQ  +F  +IT + +P + WL+    +  +    +  +
Sbjct: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                VL I    ++D G +TC     +G+   SA+L ++
Sbjct: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 67/267 (25%), Positives = 104/267 (38%), Gaps = 22/267 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F++V KD   I EGQ    + S+   G     I W  NG+ I+ +   R+    G+  
Sbjct: 514  PSFSSVLKDCAVI-EGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK-----------PRFTTHIQ 3156
            L I      D GTY+C A N  GQ   S  +   +K   +K           P     +Q
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             +  LK    +    TV    +P  ++ W HNG  ++ S             L I     
Sbjct: 628  GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFP 687

Query: 3217 HDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPST 3276
             D+G Y C A+N  GE  T+A +          +  QP  ++K R + +  G        
Sbjct: 688  EDTGTYTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWFISKPRSVTASLGQSVLISCA 743

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFE 3303
             + +P   +  ++D   L +  + HFE
Sbjct: 744  IAGDPFPTVHWLRDGKALCK-DTGHFE 769



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 37/123 (30%), Positives = 65/123 (52%), Gaps = 4/123 (3%)

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
            +K++  ED S+       E   +  P F   +    ++ EG +A ++C+IE YPDP   V
Sbjct: 1732 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPE--V 1788

Query: 1879 EWYFNGKVLQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             W+ + + ++    ++   D  G  +L I  V G+D  +YTCKA+N+LG+A  +    V+
Sbjct: 1789 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 1848

Query: 1938 SKE 1940
            + E
Sbjct: 1849 TME 1851



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 59/227 (25%), Positives = 96/227 (42%), Gaps = 27/227 (11%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++ AP F++ LK    ++EGQ   L+  V  R  P  +I W  NG  +      +ST + 
Sbjct: 510  MEVAPSFSSVLKDC-AVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 563

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI-EDRHWLLGESLHPDSLDRIGAL 2756
            G+  L I     +D G YTC A N LG+   +A + + E +     E L P +  +  A 
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA- 622

Query: 2757 XXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL 2816
                              +F+  L+++   +G  +     V+ S +P  ++ W  N   +
Sbjct: 623  -----------------PIFLQGLSDLKVMDGSQV--TMTVQVSGNPPPEVIWLHNGNEI 663

Query: 2817 PSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +      +  SL I   + ED+G YTC+A NS G   T   L
Sbjct: 664  QESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 5/143 (3%)

Query: 2319 AINALGHCTS-AISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPV 2377
            A+ A+G  +S A+   ++ + S       P   EK+   E         + E     +P 
Sbjct: 1699 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1758

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSM 2436
            F++ +++++ + EG  A FDC++    DP  +V WF++++ I +S      +D  G  S+
Sbjct: 1759 FSKTIRDLE-VVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSL 1815

Query: 2437 TISHVRDEDEGVYMCRASNLLGE 2459
             IS V  +D+  Y C+A N LGE
Sbjct: 1816 IISDVCGDDDAKYTCKAVNSLGE 1838



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 62/232 (26%), Positives = 94/232 (40%), Gaps = 28/232 (12%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   LK    ++EGQ   F  +   +      + W  NG+ I  A   ++  + G   
Sbjct: 514  PSFSSVLKDC-AVIEGQD--FVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I     ED G YT +A NA G+   SA +TV  + S                  +S++
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS----------------RKSEY 611

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            + P   +     + P+F+Q LS+   V +G  + +  ++   G+P   V W HNG  +  
Sbjct: 612  LLP---VAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQE 665

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
               F         +L I      DTG YT  A N  G   T A++ V E  D
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 55/227 (24%), Positives = 89/227 (39%), Gaps = 11/227 (4%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            + EG+ L L+ QV   +DP   I W  NGK L+      L+ +    ++ +      D G
Sbjct: 1109 VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRG 1166

Query: 2983 IYTCKAYNKRGEAFTSSTVYC----TSKDNLIERTQHPKGTEGLEKIQNLED--SLRKEP 3036
            +Y C A N  G+A  S  V       S++      +  +    L  +   E   +++K+P
Sbjct: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
              +       PP+    F +   +  G+       +  TG Q +   W    K I+ S  
Sbjct: 1227 APKTPPKAAMPPQIIQ-FPEDQKVRAGESVELFGKV--TGTQPITCTWMKFRKQIQDSEH 1283

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            I+   +     L IL  +    G Y+    NK G  +  V L  VDK
Sbjct: 1284 IKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 67/228 (29%), Positives = 98/228 (42%), Gaps = 28/228 (12%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F + +KD  ++ EG    F  +    G    R+ WL +G+P++ + R T     G   
Sbjct: 514  PSFSSVLKD-CAVIEG--QDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTC--EAGVAE 567

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I+     D G YTC A NA+GQ + SA +T+  KK             K +YL   + 
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK----------SSRKSEYLLPVAP 617

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
             SK T         P FL  L    K+++G       +V    +    V W  NG +I  
Sbjct: 618  -SKPT--------APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 665

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            +            +L I  V  ED+G YT  A N+AGE +  A +TV+
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F +  ++    +G  A+F+ K+ G P P V W +    + E   + + Y+E  G+ SL
Sbjct: 1757 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1815

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            +I  +   D+ +YTC A N  GEA C+
Sbjct: 1816 IISDVCGDDDAKYTCKAVNSLGEATCT 1842



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 46/151 (30%), Positives = 74/151 (49%), Gaps = 5/151 (3%)

Query: 710  TCRAVSATGVAETKAVLH-VTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ 768
            T  AV A G   + A++  ++ R +   +   P   + ++  ED S+   +   EE+   
Sbjct: 1696 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1755

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827
            +P F + ++DL E+ EG  A F+ ++    DP   V W+KD + I  S      ++  G 
Sbjct: 1756 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1812

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
             SL I  +  +D   YT +AVN LGEA  TA
Sbjct: 1813 CSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1843



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 20/239 (8%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P FI   ++  ++E    +FE RV    +P  ++ W+RNG+ + SG R+     + G  S
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEP--QVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  V+ ED G+Y C A N  G    + T+      ++ ++    + + +      +  
Sbjct: 91   LVIHAVHEEDRGKYTCEATN--GSGARQVTV------ELTVEGSFAKQLGQPVVSKTLG- 141

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
               ++++    T   ++    + PP+F T++  +  + E +  +F C++   G P  +V 
Sbjct: 142  --DRFSASAVETRPSIWG---ECPPKFATKL-GRVVVKEGQMGRFSCKI--TGRPQPQVT 193

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
            W     PL    R +     G   +    V  +D G Y C   N  G     A +   G
Sbjct: 194  WLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 5/157 (3%)

Query: 983  TCRAYNAIGQATTSANLTIVT-KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            T  A  AIG+ ++ A ++ ++ +K        P   EK++  ED S+       E K   
Sbjct: 1696 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1755

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-YHDFGY 1100
            KP F   ++   ++VEG +A F+ ++E   D    V W+ + + I  +   Q  Y + G 
Sbjct: 1756 KPYFSKTIRDL-EVVEGSAARFDCKIEGYPD--PEVVWFKDDQSIRESRHFQIDYDEDGN 1812

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             +L I+ V  +D   YT  A N+ GEA  +A   VET
Sbjct: 1813 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVET 1849



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 43/140 (30%), Positives = 65/140 (46%), Gaps = 5/140 (3%)

Query: 4374 GDKEITRKITSTETTE-IEHKAQTQERVVEGPV--KPSKPPIFTKKMQPCRVFEHEQARF 4430
            G K  T   TS    E +E +    +  +E     KP   P F+K ++   V E   ARF
Sbjct: 1717 GRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARF 1776

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489
            + + +G P P + W++++  I+ S  FQI +       LII  V  +D A +   A N  
Sbjct: 1777 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1836

Query: 4490 GTAKCSANLVVEEKRRQGRG 4509
            G A C+A  +V E   +G G
Sbjct: 1837 GEATCTAEHIV-ETMEEGEG 1855



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 70/311 (22%), Positives = 117/311 (37%), Gaps = 34/311 (10%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            ++EGQ   L+  V  +  P  +I W  NG+ ++     + T + G   L + D    D G
Sbjct: 525  VIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHG 579

Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDD 3042
             YTC A N  G+   S+ V           T H K +    K + L      +P      
Sbjct: 580  TYTCLAENALGQVSCSAWV-----------TVHEKKSS--RKSEYLLPVAPSKP------ 620

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
                 P F     D+  +   Q+     ++  +G+    + W +NG  I+ S        
Sbjct: 621  ---TAPIFLQGLSDLKVMDGSQVT---MTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
                 L I      D+GTY+C A N  G+      L   +   G +P F +  +++    
Sbjct: 675  GTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA-S 733

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST-RIKTVSDFGFVVLDIAYTQNHDSGE 3221
             GQS    C +    DP   + W  +G+ +   T   + + +     L +   Q   +G+
Sbjct: 734  LGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791

Query: 3222 YVCRAYNKYGE 3232
            Y     N+ GE
Sbjct: 792  YEILLKNRVGE 802



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 59/243 (24%), Positives = 97/243 (39%), Gaps = 17/243 (6%)

Query: 258  RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            RS    + P   QK ++  + EG     Q Q+S +P   + W  NG+ L  + K  I++ 
Sbjct: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQ 1148

Query: 318  HNHT-TLRVRNTQKSDSGHYTLLAENPNG-----CIVTSGYLAVESPTESYVQDQRSQYI 371
                 ++ +      D G Y  +A+N  G     C VT         T++     R    
Sbjct: 1149 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208

Query: 372  TDTQQRETEERIEISEK---------ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            +      TE    + +K         A+ PQ ++  +D+ V  G+      +VTG     
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             TW    +QI+D  + K+  +E+G+  L I        G  T +  NK G    Q  L V
Sbjct: 1269 CTWMKFRKQIQDSEHIKVENSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327

Query: 483  IEK 485
            ++K
Sbjct: 1328 VDK 1330



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 8/123 (6%)

Query: 43  HFTRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPV 102
           H ++   +   S  D  P+T   P    PP      +N    +G  AKFEG++RG P P 
Sbjct: 11  HISKTSLSVDPSRVDSMPLTEA-PAFILPP------RNLCIKEGATAKFEGRVRGYPEPQ 63

Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           V+W R   P+    ++ +    + G  SL+I  +   D G+YTC A N  G    +V + 
Sbjct: 64  VTWHRNGQPITSGGRFLLDCGIR-GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122

Query: 163 PEG 165
            EG
Sbjct: 123 VEG 125



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 61/212 (28%), Positives = 85/212 (40%), Gaps = 26/212 (12%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG     +C V     P +T  W  NGQ I+     R+T + G   L I     ED GTY
Sbjct: 527  EGQDFVLQCSVRGTPVPRIT--WLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 581

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPP 2242
             C A N LG+   +C+  V  H             +  R+ E       + V   K + P
Sbjct: 582  TCLAENALGQV--SCSAWVTVHEK-----------KSSRKSEYL-----LPVAPSKPTAP 623

Query: 2243 RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
             F+  L     V +G       QV    +P   + + HNG  +Q +  FH        SL
Sbjct: 624  IFLQGL-SDLKVMDGSQVTMTVQVSG--NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             IQ   PED G Y+ +A N+ G   +   +TV
Sbjct: 681  WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 63/218 (28%), Positives = 91/218 (41%), Gaps = 28/218 (12%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F + L+    V EG+    +C V     P  RI +  NG+ +Q A     T + G   
Sbjct: 514  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYARS---TCEAGVAE 567

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L IQ  +PED G Y+  A NALG  + +  +TV  K S    S++ E             
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS----SRKSE------------- 610

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            +  P  P   T   P+F Q L ++  + +G       ++   G+P  +V W  N   I++
Sbjct: 611  YLLPVAPSKPT--APIFLQGLSDL-KVMDGSQVTMTVQV--SGNPPPEVIWLHNGNEIQE 665

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            S            S+ I  V  ED G Y C A N  GE
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGE 703



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 61/237 (25%), Positives = 86/237 (36%), Gaps = 35/237 (14%)

Query: 3558 PEFTTTPSDLILSENSSAHFEC--RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            P F++   D  + E      +C  R  PV     R+ W  NG+P+      ++  + G  
Sbjct: 514  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVP----RITWLLNGQPI---QYARSTCEAGVA 566

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I      D G YTC A N  G+  VSC   V              H K  +   + L
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQ--VSCSAWVT------------VHEKKSSRKSEYL 612

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
                     + +   KP  P F   + D + V +G  V    +V   G+P   + W HNG
Sbjct: 613  ---------LPVAPSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 660

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
                     H        +L I  ++  D G YTC A N  G   T A +T     D
Sbjct: 661  NEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 5/115 (4%)

Query: 1953 EKIQYLEDDSR-YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
            EK++  ED S+ +  AV ++   V KP F K I++ EV EG     +  +    DP   V
Sbjct: 1732 EKLESEEDVSQAFLEAVAEEKPHV-KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EV 1788

Query: 2012 EWYCNGRPVQQGHRFKTTYDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
             W+ + + +++   F+  YD  G  +L I     +D   Y CKA N++GEA  T+
Sbjct: 1789 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1843



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 3/130 (2%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +L   ED S+    +  +E     P F+  ++D+ V E  AA F+ ++    DP+  V W
Sbjct: 1733 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1790

Query: 1747 LRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             ++   I  S      +D  G  +L +  V  +D   YTC+A+N LGEA  ++   V++ 
Sbjct: 1791 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETM 1850

Query: 1806 ASLQLESQHE 1815
               + E + E
Sbjct: 1851 EEGEGEGEEE 1860



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 53/238 (22%), Positives = 94/238 (39%), Gaps = 12/238 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F   ++D+ VAE +    + ++    DP   + W  NG  ++ +  +    +    +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-------QSKASLQLESQHESALQKIQ 1822
            ++++    ED G Y C A N+ G+A  S  + V        +KA      + +S+L  + 
Sbjct: 1155 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1823 QLEDSSRYQRREDVEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
              E  +  +++   +     A P  I Q     K+  G+S     ++     P +   W 
Sbjct: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG-TQP-ITCTWM 1272

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
               K +Q     +  N    + L IL    E  G YT    N LG   + + L V  K
Sbjct: 1273 KFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 37/146 (25%), Positives = 68/146 (46%), Gaps = 4/146 (2%)

Query: 1251 TVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            T  AV  +G   + A++  +  R        +    E+++  ED ++   +   +     
Sbjct: 1696 TGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHV 1755

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD-YV 1368
             P FS+ + ++E VEG+    +C+++   D    V WF + + I+    F+  Y+ D   
Sbjct: 1756 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNC 1813

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEA 1394
            +L +  V  +D   YTC+A N LGEA
Sbjct: 1814 SLIISDVCGDDDAKYTCKAVNSLGEA 1839



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 3/134 (2%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + +  + +G+     + E   S+    PPK A K     ++EG   +F  +++G P+P+V
Sbjct: 133 QPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-- 355
           TW K    L  S +  +   +    L +    + D G YT L  N +G    S  L++  
Sbjct: 193 TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252

Query: 356 -ESPTESYVQDQRS 368
            +S   S+V++ ++
Sbjct: 253 LDSANRSFVRETKA 266



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 61/232 (26%), Positives = 91/232 (39%), Gaps = 28/232 (12%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F+  +KD   V EG      C V   G P  RI W  NG+P        +  + G   
Sbjct: 514  PSFSSVLKD-CAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPI---QYARSTCEAGVAE 567

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L I      D G YTC A N  G  + +A +T   K+            S  K + L   
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK------------SSRKSEYL--- 612

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
             +  AP +     T P F+  +    ++  +G +    V+   +P   + W  NG  +  
Sbjct: 613  -LPVAPSK----PTAPIFLQGLSD--LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
               +         SL I  V+ ED+G Y C A N  GE  T+A ++ ++  D
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 6/122 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + E+R E   +  AP F +  QD  V EGK     C+V+  P   + W +N + ++    
Sbjct: 1086 DNEKRSE--SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-K 1142

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE---KEQVVAPKFV 494
              IL  E    ++ I    L D G+  CVA+N +G+    C++ V +    E   AP+  
Sbjct: 1143 FIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202

Query: 495  ER 496
             R
Sbjct: 1203 SR 1204



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 61/244 (25%), Positives = 99/244 (40%), Gaps = 16/244 (6%)

Query: 2226 QGHSTRIEVE---EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
            +GH+   + E   E + + P F  +L+   HV EGK    +CQV    DP   I +  NG
Sbjct: 1079 RGHAGTTDNEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSS--DPPATIIWTLNG 1135

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV----TAKG 2338
            K L++     ++ +    S+ I+  + ED G Y   A N  G    +  +TV     ++ 
Sbjct: 1136 KTLKTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195

Query: 2339 SIISE--SQRPE-GLEKIRELESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNIQEGQTA 2394
            +   E  S+RP+  L  +   ES    K+   P+ P     P           ++ G++ 
Sbjct: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255

Query: 2395 HFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
                ++   G   +   W +  K I+DS  I   +      +TI   R E  G Y     
Sbjct: 1256 ELFGKV--TGTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVE 1313

Query: 2455 NLLG 2458
            N LG
Sbjct: 1314 NKLG 1317



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 54/235 (22%), Positives = 91/235 (38%), Gaps = 14/235 (5%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F + L ++   EG  + L+C++    D    + W  NGK +KT      + E    +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV------IAKKDLILESQHP-SGLEKIQ 1422
            + +     ED G+Y C A N  G+A  SC + V         K   ++S+ P S L  + 
Sbjct: 1155 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1423 YLEDTSRYKKTDI--IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEW 1480
              E  +  KK           + P+ +  P+  + V  G+ V    K+       +   W
Sbjct: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKV--TGTQPITCTW 1271

Query: 1481 FKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             K  + +      +  +      L I+    E  G YT    N +G+ +    LT
Sbjct: 1272 MKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1326



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 53/251 (21%), Positives = 93/251 (37%), Gaps = 10/251 (3%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E   E     P F + LQD+  + EG+    + Q++  SDP   + W  +G+ +  +  I
Sbjct: 1088 EKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFI 1144

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV----AARSTVTADLGIP 875
                     S++I     ED G Y   A N  G+A  +  + V    A+ +T   ++   
Sbjct: 1145 ILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935
              +  +                     P++   P+     +DQ  ++ G       ++  
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ-KVRAGESVELFGKVT- 1262

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             G   +   W+K  + ++ S  I    +     LTI +      G YT    N +G    
Sbjct: 1263 -GTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQA 1321

Query: 996  SANLTIVTKKD 1006
              NLT+V K D
Sbjct: 1322 QVNLTVVDKPD 1332



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 5/100 (5%)

Query: 3687 IEDEKPN-PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
            + +EKP+  P F+  I+D ++V EG    FDC++E   DP   + WF + +         
Sbjct: 1748 VAEEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQ 1804

Query: 3746 -TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
               ++ G  +L I  +   D  +YTC+A N  G AT TA+
Sbjct: 1805 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1844



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 5/108 (4%)

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            E  +++ +  +    +E+P V   P F   I+   V E    RF+C++E   DP+  + W
Sbjct: 1735 ESEEDVSQAFLEAVAEEKPHVK--PYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VVW 1790

Query: 3866 YRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            +++ + +     ++  YD  G  SL I  V  +D  +Y C+AVN  GE
Sbjct: 1791 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1838



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 58/258 (22%), Positives = 90/258 (34%), Gaps = 10/258 (3%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G++GT D        G  P F     D+ ++E      +C++   +D    + W  NGK 
Sbjct: 1080 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKT 1137

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI--IL 3657
            L T   +    +     + I      D GLY C A N  G+A  SC++ V          
Sbjct: 1138 LKTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1197

Query: 3658 EPQLPSHF-KSGTESIQKLEE--TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVH 3714
             P++ S   KS    +   E   T+ K+       +   PP+  ++  ++  V  G  V 
Sbjct: 1198 APEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI-IQFPEDQKVRAGESVE 1256

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
               +V   G   +   W    +       +   N      L I        G YT    N
Sbjct: 1257 LFGKV--TGTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVEN 1314

Query: 3775 KWGSATTTAKITCSAKRD 3792
            K GS      +T   K D
Sbjct: 1315 KLGSRQAQVNLTVVDKPD 1332



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 55/224 (24%), Positives = 86/224 (38%), Gaps = 12/224 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG  +  +C V  S DP   I W  N K L +      + + S  S+ I
Sbjct: 1100 FKQKLQDVHVAEGKKLLLQCQV--SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQ-----GKAGLEAVEQA 2890
                 ED G+Y C A N  G A  S  +    D     +T+ P+      K+ L  V   
Sbjct: 1158 EKALLEDRGLYKCVAKNDAGQAECSCQV-TVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216

Query: 2891 E-EARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949
            E +A + K   P  P      P+ II    + ++  G+ + L G+V       +   W  
Sbjct: 1217 ESDATVKKKPAPKTPPKAAMPPQ-IIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMK 1273

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
              K ++     K+ +      L ++   +   G YT    NK G
Sbjct: 1274 FRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 32/232 (13%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F + ++D   ++EGQ    +  +     P  ++ W  NG+ + +    R+  + G+  
Sbjct: 514  PSFSSVLKDCA-VIEGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401
            L I     E+ G Y C+A N LG+ S  A +    K++      L               
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL--------------- 612

Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461
                      V   K  AP+F   LS+++ + +G       +++    P  +V W  NG 
Sbjct: 613  --------LPVAPSKPTAPIFLQGLSDLK-VMDGSQVTMTVQVSGNPPP--EVIWLHNGN 661

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             ++    F          L I   +PED+G Y C A+N+ GE  T A + VQ
Sbjct: 662  EIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 4/124 (3%)

Query: 2613 PESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            P + E+++ +E       E   +      P F+  ++  + +VEG     + ++E   DP
Sbjct: 1728 PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 1786

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
              ++ WFK+  ++      +  +D  G  +L I+ +  DD   YTCKA N LGEA  TA 
Sbjct: 1787 --EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1844

Query: 2732 IKIE 2735
              +E
Sbjct: 1845 HIVE 1848



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 4/120 (3%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            EKL++ ED      +   EE+    P F+  + ++E + EG  A F+ ++    DP  +V
Sbjct: 1732 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV-EGSAARFDCKIEGYPDP--EV 1788

Query: 3455 EWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             W+ + +S++    F+  + + G   L IS    +D  +Y C+A N+ GEA  TA   V+
Sbjct: 1789 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 1848



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 55/226 (24%), Positives = 89/226 (39%), Gaps = 14/226 (6%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F  +L     ++EG+    +C++    DP   + W  NGK L++      S +    
Sbjct: 1097 APAFKQKLQD-VHVAEGKKLLLQCQVSS--DPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-------QSKESIIRDSQHESALEKI 1955
            ++ I     ED G Y C A N+ GQA  S ++ V        +K   ++  + +S+L  +
Sbjct: 1154 SVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213

Query: 1956 QYLEDDSRYKR--AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW 2013
               E D+  K+  A +        PQ  +  ++ +V  G  V L   +T     T    W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT--CTW 1271

Query: 2014 YCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
                + +Q     K         L IL A  E  G Y     N +G
Sbjct: 1272 MKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 4/100 (4%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GY 966
            KP F   I+D + + EG  A F+ ++E   D    V W KD + +  S      ++  G 
Sbjct: 1756 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGN 1812

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
             +L I  V   D   YTC+A N++G+AT +A   + T ++
Sbjct: 1813 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEE 1852



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 57/243 (23%), Positives = 98/243 (40%), Gaps = 19/243 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L+  + + EG+    + +V   SD   T+ W  NGK + +   I    +    +
Sbjct: 1098 PAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            + I     ED G+Y  VA+N AG+A+ S  +TV+   + + +   +    K+R  + S  
Sbjct: 1155 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT---KAPEMKSRRPKSS-- 1209

Query: 1163 VEPMYQIEEIS--KSKPVFVQP--LSNPPPV---SEGKNIHLECRLEPMGDPT----MRV 1211
            + P+   E  +  K KP    P   + PP +    E + +     +E  G  T    +  
Sbjct: 1210 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1269

Query: 1212 EWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             W    + +      K         L I+ A     G YT+   N LGS      + V++
Sbjct: 1270 TWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329

Query: 1272 RSD 1274
            + D
Sbjct: 1330 KPD 1332



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 3/131 (2%)

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
            E+++  ED S+     + +E     P  + +++++E+ EG  A F+ ++    D   +V 
Sbjct: 1732 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVV 1789

Query: 1613 WYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
            W+ +++ ++    F  + +  G  +L I     +D   YTC+A+N+LGEA  +   IV +
Sbjct: 1790 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVET 1849

Query: 1672 KKSIYLESQHE 1682
             +    E + E
Sbjct: 1850 MEEGEGEGEEE 1860



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           P +P+ PIF Q   + +   G       ++ GNP P V W      + E   +   + ++
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQR 674

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
               SL I+++ P D G YTC A N  GE
Sbjct: 675 GTQHSLWIQEVFPEDTGTYTCEAWNSAGE 703



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 33/130 (25%), Positives = 63/130 (48%), Gaps = 7/130 (5%)

Query: 2201 VAGHRNIILDTQHPNGLEKIRQLE--AQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            ++G ++       P   EK+   E  +Q     +  E+P + P  + ++      V EG 
Sbjct: 1715 LSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP--YFSKTIRDLEVVEGS 1772

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGYVSLDIQHCVPEDAGEYSV 2317
             A F+C++E   DP   + ++ + ++++ +  F I +D  G  SL I     +D  +Y+ 
Sbjct: 1773 AARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1830

Query: 2318 KAINALGHCT 2327
            KA+N+LG  T
Sbjct: 1831 KAVNSLGEAT 1840



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 25/87 (28%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYE 4785
            +RD+ V EG  A+F  +I     P + W ++   I E+  FQ+ + E  N  L+I +   
Sbjct: 1763 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1822

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +D   +TC+A  + G+   +A+ +V++
Sbjct: 1823 DDDAKYTCKAVNSLGEATCTAEHIVET 1849



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 56/231 (24%), Positives = 89/231 (38%), Gaps = 28/231 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P F+ VL   + + EGQ    +  V   G P  R  W +NG  ++     R+T + G   
Sbjct: 514  PSFSSVLKDCAVI-EGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L I   +  D G Y C A N  G                        +W  +  K+++  
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCS-------------------AWVTVHEKKSSRK 608

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                + V      APIF   L    K+++G  V +  QV     P  ++ W  NG  +  
Sbjct: 609  SEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQVTMTVQVSGNPPP--EVIWLHNGNEIQE 665

Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
                         +L I  +  +D+G YTC+A N  GE  + A + +++ H
Sbjct: 666  SEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIK 4749
            GD K VA +   + +++              PA + P R++ + EG  A+F+ ++    +
Sbjct: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            P + W R G  I     F ++  G      L+I   +EED G +TC AT  +G  + + +
Sbjct: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 4808 LVVK 4811
            L V+
Sbjct: 121  LTVE 124



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 3/116 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMHDFGYVA 1769
            P F    +   V ENQ   F   +   G PK  V W   G P+      +    D G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            L +      DSGTY+C A N  G+   S TL V+  A +++     S L+    +E
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F+  L  +  M+G ++    ++   G+P  ++ WL NG  I+ S  F    R    SL
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +  +  +D+G YTC A ++ G   T+AVL V
Sbjct: 681 WIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 57/237 (24%), Positives = 91/237 (38%), Gaps = 33/237 (13%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F   L+D   + EG++  F  Q +    P  R+ W  +G+PI  +    S    G   
Sbjct: 514  PSFSSVLKDCAVI-EGQD--FVLQCSVRGTPVPRITWLLNGQPIQYAR---STCEAGVAE 567

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L+I     ED G+YT  A N LG+   +A + V  + +         +  Y+        
Sbjct: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-------SRKSEYLLPVA---- 616

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                         P     P F   + D + + +G       ++   G+    V WL +G
Sbjct: 617  -------------PSKPTAPIFLQGLSD-LKVMDGSQVTMTVQVS--GNPPPEVIWLHNG 660

Query: 950  RPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
              ++ S            +L I+ V   D G YTC A+N+ G+  T A LT+    D
Sbjct: 661  NEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 27/226 (11%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F   LK    +EG     +  +   G P  +I WL NGQ I+ +    S    G   L
Sbjct: 514 PSFSSVLKDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 568

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
            +     +D G YTC A +A G     A + V  + +  +                 S+Y
Sbjct: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK-----------------SEY 611

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
               +  + T+  P F++ L DL ++ +G       Q++   +P   V W  +G  I  S
Sbjct: 612 LLPVAPSKPTA--PIFLQGLSDL-KVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQES 666

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                       SL I  +  ED G+YT  A N  GE  + A + V
Sbjct: 667 EDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/229 (25%), Positives = 81/229 (35%), Gaps = 27/229 (11%)

Query: 3988 METTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYL 4047
            +E   F  Q +  G P  ++ W  NG+P+ +  R T   + G   ++     PED G Y 
Sbjct: 526  IEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RST--CEAGVAELHIQDALPEDHGTYT 582

Query: 4048 CRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKA 4107
            C A N  G     A +                H K  +  R+ E    V P      SK 
Sbjct: 583  CLAENALGQVSCSAWVTV--------------HEK--KSSRKSEYLLPVAP------SKP 620

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH- 4166
              P     L D + V +G       +V+G+P P V+WL NGN I     +     G  H 
Sbjct: 621  TAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679

Query: 4167 FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
              I +    DTG                  L V   HD  +    + PR
Sbjct: 680  LWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 11/154 (7%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT-TDSGTYSCRATNKWGQAEISVK-LEC 3140
            +W   G  + A  R+ ++     ++  + G K+ T S T    A     + ++S   LE 
Sbjct: 1692 KWQKTGNAVRAIGRLSSM----AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1747

Query: 3141 VDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199
            V + K   KP F+  I+++E + +G +A F+C +    DP+  + W+ + Q +R S   +
Sbjct: 1748 VAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQ 1804

Query: 3200 -TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                + G   L I+     D  +Y C+A N  GE
Sbjct: 1805 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1838



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 630  EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            E++ +  P F   ++ +  +EG    F+ +IE   DP  ++ W K+ QSI  S  F   +
Sbjct: 1750 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDY 1807

Query: 690  -RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKA 724
               G  SL +  +   D  +YTC+AV++ G A   A
Sbjct: 1808 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1843



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP F+  L +   + EG++   +  +  T  P  ++ W  NG+ ++     R+ C+ G  
Sbjct: 513  APSFSSVLKDCAVI-EGQDFVLQCSVRGTPVP--RITWLLNGQPIQYA---RSTCEAGVA 566

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQL----PKGMEGTI-- 3532
             L I    PED G Y C A N  G+   +A + V  K++      L    P      I  
Sbjct: 567  ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECR 3580
              ++ L+   G+  T+T +     PPE     +   + E+   HFE R
Sbjct: 627  QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 19/282 (6%)

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQ 1979
            + +  +G A     L   SKE + +D +++   ++      D+  +   Q  +     P 
Sbjct: 1045 ETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTA-----PA 1099

Query: 1980 FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDI 2039
            F + +++  V EG  + L+  ++  +DP   + W  NG+ ++       + +    ++ I
Sbjct: 1100 FKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 2040 LYAYAEDTGTYMCKATNAVGEAVTTSSVKVD---AKSGLYLDTLDEQRLKKI------QE 2090
              A  ED G Y C A N  G+A  +  V VD   A        +  +R K         E
Sbjct: 1158 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217

Query: 2091 LEKYERPKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
             +   + KP  +  P    P  +      + ++ G+      +V       +T  W    
Sbjct: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQPITCTWMKFR 1275

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            ++I+     +  +      L IL    E  G Y     NKLG
Sbjct: 1276 KQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F   L+    + EG+ + L+ QV   +DP   I W  NG TL T   +  + +  L 
Sbjct: 1097 APAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            ++SI     +D G+Y C A N  G+A  +  + ++D
Sbjct: 1154 SVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDD 1189



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 51/242 (21%), Positives = 88/242 (36%), Gaps = 12/242 (4%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            E +G AP F   L ++ ++ EG+    + +++   DP   + W  NGK+LK  ++F    
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT-TKFIILS 1147

Query: 3474 DFGFVI-LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ---GKRNIILESQLPKGME 3529
              G +  + I     ED G Y C A N+ G+A  +  + V       N        +  +
Sbjct: 1148 QEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207

Query: 3530 GTIDKIAALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
             ++  +   E  +       P+   ++  PP+    P D  +    S     ++      
Sbjct: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV--TGTQ 1265

Query: 3588 SMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
             +   W    K +     +K  N      L I    Q   G YT    N+ G       L
Sbjct: 1266 PITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325

Query: 3648 QV 3649
             V
Sbjct: 1326 TV 1327



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 42/151 (27%), Positives = 69/151 (45%), Gaps = 9/151 (5%)

Query: 1127 AQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNP 1186
            A +S     ++ +   TS ++    E    + ++ F+E +   EE    KP F + + + 
Sbjct: 1710 AMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQA-FLEAV--AEEKPHVKPYFSKTIRDL 1766

Query: 1187 PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFVALDIIHATSA 1245
              V EG     +C++E   DP   V WF + +S+     F+  YD  G  +L I      
Sbjct: 1767 EVV-EGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1823

Query: 1246 DTGEYTVRAVNHLGSAHTSA--IVRVIERSD 1274
            D  +YT +AVN LG A  +A  IV  +E  +
Sbjct: 1824 DDAKYTCKAVNSLGEATCTAEHIVETMEEGE 1854



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 4078 PKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGH 4137
            P    + EK+   E   Q   E V EE K    P F      + V EG  ARF C++ G+
Sbjct: 1725 PTSPLNAEKLESEEDVSQAFLEAVAEE-KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1783

Query: 4138 PKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P P V+W  +  +I     +++ YD
Sbjct: 1784 PDPEVVWFKDDQSIRESRHFQIDYD 1808



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT--YDGMYHFD 4168
            P F+  P  + ++EG  A+F  RV G+P+P+V W  NG  I +G R+ L     G +   
Sbjct: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92

Query: 4169 IPKTRQYDTGK 4179
            I    + D GK
Sbjct: 93   IHAVHEEDRGK 103



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 16/236 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-S 695
            P F   L+ V   EG K+  + ++    DP   I W  NG++++ +++F  + + G + S
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLK-TTKFIILSQEGSLCS 1154

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERT------SQHPE-TLQYIQ 748
            + +    ++D G Y C A +  G AE    + V      E T      S+ P+ +L  + 
Sbjct: 1155 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 749  QLEDYS--KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
              E  +  K +       + +  PQ I+  +D  +++ G +     ++T     T    W
Sbjct: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPIT--CTW 1271

Query: 807  YKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             K  + I  S  I    +     L I+  R E  G YT+   NKLG   +  ++ V
Sbjct: 1272 MKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 3/110 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS-RVKTINDFGFVI 3616
            P+F + P    + EN +  F C +  +      V WF  G P+      ++   D G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGI--PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            L +     RD+G Y+C A+N  G+ + S  LQV+    + + P   S  K
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLK 521



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 16/245 (6%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            +S+G  P F   +Q++  + +G+    +C V    DP   I W  NG+ ++ +  I    
Sbjct: 1092 ESQGTAPAFKQKLQDVH-VAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1148

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATIN----CYGKGGVYLESLQP-D 3255
            +     + I      D G Y C A N  G  E   + T++            ++S +P  
Sbjct: 1149 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208

Query: 3256 SLAKIRELESLQGAQQQ-TPSTP--SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDP 3312
            SL  +   ES    +++  P TP  +A PP+ I Q  +  K+  G+S     ++      
Sbjct: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQII-QFPEDQKVRAGESVELFGKVTGTQ-- 1265

Query: 3313 DLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +   W    K++      +  +      L IL   +E+ G Y  +  NKLG    + NL
Sbjct: 1266 PITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325

Query: 3373 KCTSK 3377
                K
Sbjct: 1326 TVVDK 1330



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 40/129 (31%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 44  FTRQMTTQVESS--GDRQPITA--GRP---GEPSPPIFEQIFKNARFAQGGNAKFEGKLR 96
           F +Q+   V S   GDR   +A   RP   GE  PP F          +G   +F  K+ 
Sbjct: 127 FAKQLGQPVVSKTLGDRFSASAVETRPSIWGE-CPPKFATKLGRVVVKEGQMGRFSCKIT 185

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P V+W +   PL    + S+  +E+ G   L I  +   D G YTC   N  G+A 
Sbjct: 186 GRPQPQVTWLKGNVPLQPSARVSV--SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243

Query: 157 CSVYIQPEG 165
            S  +  +G
Sbjct: 244 MSAELSIQG 252



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 37/239 (15%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            ++   P F + +K   V E +    +C V  +  P  RI W  NG+ +      R+  + 
Sbjct: 509  VMEVAPSFSSVLKDCAVIEGQDFVLQCSV--RGTPVPRITWLLNGQPIQYA---RSTCEA 563

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            G   L I     ED G Y C A N  G+      +SC     +       +  ++SE L 
Sbjct: 564  GVAELHIQDALPEDHGTYTCLAENALGQ------VSCSAWVTV----HEKKSSRKSEYL- 612

Query: 3945 QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPN 4004
             +     K T+ ++L                    Q  + L  M+ ++    +   G+P 
Sbjct: 613  -LPVAPSKPTAPIFL--------------------QGLSDLKVMDGSQVTMTVQVSGNPP 651

Query: 4005 MKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
             +V W  NG  +     F         ++    V+PED+G Y C A N  G   T+AV+
Sbjct: 652  PEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 54/241 (22%), Positives = 84/241 (34%), Gaps = 15/241 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  +++D + V EG  +   C+V    DP   I W  NG+   T   +    +    +
Sbjct: 1098 PAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER- 3813
            + I+     D G Y C A N  G A  + ++T          ++ P+  S      L   
Sbjct: 1155 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVD-DAPASENTKAPEMKSRRPKSSLPPV 1213

Query: 3814 -GRISDA-------PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
             G  SDA       PK  P  + PP+ I   +   V   E V    +V   +   +   W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQ--PITCTW 1271

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             +  K +      +         L IL    E  G Y     N  G    +  ++    P
Sbjct: 1272 MKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331

Query: 3926 D 3926
            D
Sbjct: 1332 D 1332



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 33/104 (31%), Positives = 45/104 (43%), Gaps = 4/104 (3%)

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH-R 2157
            P+E ++    P F +   S E +KE     F C V  I  P +   WF  G  +R     
Sbjct: 404  PMEGQRDSAFPKFESKPQSQE-VKENQTVKFRCEVSGIPKPEVA--WFLEGTPVRRQEGS 460

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 D G   L +L     DSGTY C A+N  G+   + TL+V
Sbjct: 461  IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVA 2036
            P+F    ++ EV E   V     ++ +  P   V W+  G PV++       Y D G   
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKP--EVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            L +L A   D+GTY C A+NA G+   + +++V+
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVE 505



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 4/84 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY-DFGYV 4031
            P+F ++ QSQ  + E +T KF C+++  G P  +V WF  G P+  +     +Y D G  
Sbjct: 414  PKFESKPQSQ-EVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYG 4055
             +        DSG Y C A+N  G
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQG 494



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/86 (25%), Positives = 41/86 (47%)

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            + Q  AP F ++   ++V EG+ ++L  +    P   I W  +G  +     + +  +G 
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
              ++ I +A   D   Y+C A+N AG
Sbjct: 1152 LCSVSIEKALLEDRGLYKCVAKNDAG 1177



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            E  G  P F   L  + ++ EG +   +C+V   +DP  TI W  NG+ ++       + 
Sbjct: 1092 ESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQ 1148

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +    ++ I     ED G Y C A N  G+A  +C + V
Sbjct: 1149 EGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTV 1187



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            P E    S  PKF ++ +S  V+E++ V+F C V     PK  + W+  G  +       
Sbjct: 404  PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEV--SGIPKPEVAWFLEGTPVRRQEGSI 461

Query: 3880 TVY-DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
             VY D G   L +L     DSG Y C A N  G+     T+  ++L
Sbjct: 462  EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERL 507



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD-FSYVSLD 2834
            F   + ++   EG    F+C +E   DP  ++ WF +++ +     ++  +D     SL 
Sbjct: 1759 FSKTIRDLEVVEGSAARFDCKIEGYPDP--EVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1816

Query: 2835 ITHTYEEDSGIYTCKATNSKGSAT 2858
            I+    +D   YTCKA NS G AT
Sbjct: 1817 ISDVCGDDDAKYTCKAVNSLGEAT 1840



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLTYDGMYHFD 4168
            P F S P +  V+E +  +F C V+G PKP V W L G  +    GS       G ++  
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 4169 IPKTRQYDTG 4178
            + K R  D+G
Sbjct: 474  LLKARTRDSG 483



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 3/115 (2%)

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592
            +K+ + E  S        E +    P F+ T  DL + E S+A F+C++    D    V 
Sbjct: 1732 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE--VV 1789

Query: 3593 WFHNGKPLLTGSRVKT-INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            WF + + +      +   ++ G   L I  V   D   YTCKA N  GEAT + +
Sbjct: 1790 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1844



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 3/113 (2%)

Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHDFGYVALDIASVRA 1110
            + ++ E Q+  F  R E        V W+  G  +      I+ Y D G   L +   R 
Sbjct: 422  SQEVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKART 479

Query: 1111 EDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFV 1163
             DSG Y+  A NA G+   S ++ VE  + ++ +     + +    IE   FV
Sbjct: 480  RDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNKYS 119
           +T   P + + P F    ++   + G +      + G+P P V W R  KA   +   + 
Sbjct: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769

Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSV 159
           +  NE     +L++K++ P   G+Y    +N+ GE  C V
Sbjct: 770 VLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQV 807



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++ ++ EG+     C++    DP   + W  N K ++ +  I  + +    S
Sbjct: 1098 PAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            ++I     ED G+Y C A N  G+
Sbjct: 1155 VSIEKALLEDRGLYKCVAKNDAGQ 1178



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 31/109 (28%), Positives = 44/109 (40%), Gaps = 2/109 (1%)

Query: 470  KSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            +S E   Q  L  + +E+  V P F +    L V EG     + +  G P P + W KD 
Sbjct: 1735 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1794

Query: 529  VPIIPNPELRI-HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
              I  +   +I + + G  +L I      D A Y C A N  G     A
Sbjct: 1795 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1843



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 1/100 (1%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNH 320
            P   P  ++  R+ ++ EG+ A+F  ++ G P P V WFK+ Q +  S   +I      +
Sbjct: 1753 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1812

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             +L + +    D   YT  A N  G    +    VE+  E
Sbjct: 1813 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEE 1852



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 11/104 (10%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERD 2980
            ++VEG     + ++E   DP+  + W+ + + + +   F++  D  G  +L + DV   D
Sbjct: 1767 EVVEGSAARFDCKIEGYPDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1824

Query: 2981 SGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEK 3024
               YTCKA N  GEA       CT+ ++++E  +  +G EG E+
Sbjct: 1825 DAKYTCKAVNSLGEA------TCTA-EHIVETMEEGEG-EGEEE 1860



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 21/92 (22%), Positives = 42/92 (45%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F +K+Q   V E ++   + +   +P   I W      +K +    +    +   + I
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
             +  +ED  ++  VA+N  G A+CS  + V++
Sbjct: 1158 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDD 1189



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 17/240 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP     L++V + EG++   + ++   SD    + W  N K LK+      +      +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKFIILSQEGSLCS 1154

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV------HSKKSIYLESQH-EGALPRLN 1689
            + I   L ED G Y C A N  G+A  S    V       + K+  ++S+  + +LP + 
Sbjct: 1155 VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ--AAHFEARLI--PVGDPKLRVE 1745
              E  +  ++  A        P   MP + I+  E+Q   A     L     G   +   
Sbjct: 1215 GTESDATVKKKPAP----KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W++    I+ S  +   +      L +     E  G YT    N+LG       L V  K
Sbjct: 1271 WMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE-FDYVA 1369
            P+F     + E  E   V   C +   G     V WF  G P++        YE      
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L LL     DSG Y+C A+N  G+   S  L+V
Sbjct: 472  LCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            +D  K      T P F  +++   V E + +  +C+V    DP   I W  NGK L +  
Sbjct: 1085 TDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTK 1142

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
                  +    S+ I     ED G Y C A ND G+
Sbjct: 1143 FIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQ 1178



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIV--NGSRYKL 4159
            V+E      P F+S P +VT   G+     C + G P P V WL +G  +    G    L
Sbjct: 712  VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771

Query: 4160 TYDGMYHFDIPKTRQYDTGKIEVI 4183
              + ++   + K + +  G+ E++
Sbjct: 772  QNEDVFTLVLKKVQPWHAGQYEIL 795



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQSGHRYRTSNDFGFAALDILTVYGED 1913
            ++ E Q+  + C +   P P   V W+  G  V +         D G   L +L     D
Sbjct: 424  EVKENQTVKFRCEVSGIPKPE--VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQ 1937
            SG Y+C A N  GQ   S  L V+
Sbjct: 482  SGTYSCTASNAQGQVSCSWTLQVE 505



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/138 (22%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 3013 TQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASL 3072
            T  P      EK+++ ED  +       ++     P F+   +D+ ++ EG  A ++  +
Sbjct: 1722 TGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKI 1780

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
                D  +V  WF + ++I  S   +  Y   G   L I      D   Y+C+A N  G+
Sbjct: 1781 EGYPDPEVV--WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1838

Query: 3132 AEISVK--LECVDKSKGQ 3147
            A  + +  +E +++ +G+
Sbjct: 1839 ATCTAEHIVETMEEGEGE 1856



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 14/125 (11%)

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPK----FITQIQDVTKLVEGQSAHFEARLVPV 3309
            P S     +LES +   Q      + E P     F   I+D+ ++VEG +A F+ ++   
Sbjct: 1725 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDL-EVVEGSAARFDCKIEGY 1783

Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHD----FGIVILDILYCYEENSGEYECVATNKLGR 3365
             DP+  V WF + + +     ++  +D      ++I D+  C ++++ +Y C A N LG 
Sbjct: 1784 PDPE--VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV--CGDDDA-KYTCKAVNSLGE 1838

Query: 3366 DSTKA 3370
             +  A
Sbjct: 1839 ATCTA 1843



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 4/94 (4%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYV 967
            P+F++  + Q  +KE     F  R E  G     V W  +G PV      I  + + G  
Sbjct: 414  PKFESKPQSQ-EVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L +      D+G Y+C A NA GQ + S  L +
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GF 2565
            KP F++ +    E+ EG  A ++ ++    DP +   W+ +   ++    F+  +D  G 
Sbjct: 1756 KPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEV--VWFKDDQSIRESRHFQIDYDEDGN 1812

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             +L I+ V  +D   Y CKA+N  G
Sbjct: 1813 CSLIISDVCGDDDAKYTCKAVNSLG 1837



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 10/192 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            T+++     +   P F  ++Q    + E +    +CQ++   DP   + W  NGK L   
Sbjct: 1085 TDNEKRSESQGTAPAFKQKLQD-VHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTT 1141

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV------Y 4073
                   +    +++      ED G Y C A N  G  E    +     P          
Sbjct: 1142 KFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEM 1201

Query: 4074 DSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCR 4133
             S+ PK         E +A+ +  P       KA  PP  +  P+   V  GE      +
Sbjct: 1202 KSRRPKSSLPPVLGTESDATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVRAGESVELFGK 1260

Query: 4134 VTGHPKPRVMWL 4145
            VTG       W+
Sbjct: 1261 VTGTQPITCTWM 1272



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 3/63 (4%)

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            ++  SW +  E++     A   P F S+     V EG+     C V G P PR+ WLLNG
Sbjct: 495  QVSCSWTLQVERLAVMEVA---PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551

Query: 4149 NTI 4151
              I
Sbjct: 552  QPI 554



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 2/90 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+Q  ++   A+G     + ++  +P   + WT     L +  K+ +  +++    S+
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFII-LSQEGSLCSV 1155

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             I++    D G Y C A+N  G+A CS  +
Sbjct: 1156 SIEKALLEDRGLYKCVAKNDAGQAECSCQV 1185



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 2232 IEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL-QSAA 2289
            + V+EP   + P F+++ R  T    G++    C +    DP   + +  +GKAL +   
Sbjct: 710  LTVQEPHDGTQPWFISKPRSVTASL-GQSVLISCAI--AGDPFPTVHWLRDGKALCKDTG 766

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS-MTVTAKGSIISESQRPE 2348
             F +  +    +L ++   P  AG+Y +   N +G C+  +S M   +    +   + P 
Sbjct: 767  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 826

Query: 2349 GLEKI 2353
              E +
Sbjct: 827  SCEDL 831



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 4/85 (4%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWF-RNEKLIEDSSRITKTHDFGYV 2434
            P F    Q+   ++E QT  F C +   G P  +V WF     +      I    D G  
Sbjct: 414  PKFESKPQS-QEVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
             + +   R  D G Y C ASN  G+
Sbjct: 471  YLCLLKARTRDSGTYSCTASNAQGQ 495



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 5/109 (4%)

Query: 628 GEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTS 687
           G+ D  +P  +F    +S    E   + F  R E  G P  ++ W   G  +        
Sbjct: 407 GQRDSAFP--KFESKPQSQEVKENQTVKF--RCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462

Query: 688 IFR-FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
           ++   G   L +L    +DSG Y+C A +A G       L V   A +E
Sbjct: 463 VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME 511



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 13/120 (10%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL--PSGHRYR 3879
            +EP   T P FI++ +S T    + V   C +    DP   + W R+GK L   +GH + 
Sbjct: 713  QEPHDGTQPWFISKPRSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKDTGH-FE 769

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
             + +    +L +  V    +G+Y     N  GE        C     ++LQN   R + R
Sbjct: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--------CSCQVSLMLQNSSARALPR 821



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTLNDFGFIALDIDYIYARD 3764
            +V E   V F C V   G P   + WF  G P       +    D G   L +     RD
Sbjct: 424  EVKENQTVKFRCEVS--GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481

Query: 3765 AGEYTCRATNKWGSAT 3780
            +G Y+C A+N  G  +
Sbjct: 482  SGTYSCTASNAQGQVS 497



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/88 (25%), Positives = 33/88 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P+ ++      VR GE V L  +  GT     TW K    I  +  +++      S L I
Sbjct: 1238 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTI 1297

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A+      Y    +N  GS   +  L
Sbjct: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNL 1325



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 1738 GDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            GDP   V WLR+G  + + +     + +     L +K V P  +G Y     N +GE   
Sbjct: 746  GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 805

Query: 1797 SSTLFVQSKASLQLESQHESA 1817
              +L +Q+ ++  L    E A
Sbjct: 806  QVSLMLQNSSARALPRGREPA 826



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
            +E+RSE    +   P F Q L     + EG+    + +V    DP     W +NG  LK 
Sbjct: 1087 NEKRSES---QGTAPAFKQKLQDV-HVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKT 1140

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                  + +    ++ I   +  D GLY C A N AG
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAG 1177


>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
          Length = 7962

 Score =  155 bits (376), Expect = 4e-36
 Identities = 108/404 (26%), Positives = 167/404 (41%), Gaps = 31/404 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP F +K++            E    G     + W+++   I + P  Q         L 
Sbjct: 3405 PPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLN 3464

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  +   D+ ++  VA N  G+ +CSA L V+E          PPSF  T  +V V  G 
Sbjct: 3465 LSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE----------PPSFEQTPDSVEVLPGM 3514

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +   + + GT P  V W K  +++ P     I  ED    L + E  P +SG Y C+  
Sbjct: 3515 SLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVT 3574

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG A C     V  PAT                 ++ L D  V  G  I       G 
Sbjct: 3575 NDAGSASCTTHLFVKEPAT----------------FVKRLADFSVETGSPIVLEATYTGT 3618

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P  +V W K + LI  S+   ++ T     L I E+  ED   Y C+  N AG+    A 
Sbjct: 3619 PPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEAL 3678

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            + V +P        + PL  +    G+PA  + ++    +  I W +E   +   P ++M
Sbjct: 3679 VSVLEPPYF-----IEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKM 3733

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              + N A L+I      D G ++C+A  + G V +SA LV+K++
Sbjct: 3734 QFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR 3777



 Score =  154 bits (374), Expect = 7e-36
 Identities = 119/453 (26%), Positives = 195/453 (43%), Gaps = 39/453 (8%)

Query: 4375 DKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEF 4434
            D+ +  + + T T  I   + +   ++    +   PP F  ++ P      E A FE   
Sbjct: 4785 DRSLAGQYSCTATNPIGSASSSARLIL---TEGKNPPFFDIRLAPVDAVVGESADFECHV 4841

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
             G     + W +++  I++   +QI      + L + +V   DS  +   A N  G   C
Sbjct: 4842 TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSC 4901

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
            +A L ++E+       ++PPSFT   ++ V  T G   +L+ +V G++PI V W KN  +
Sbjct: 4902 TAQLNIKER-------LIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIE 4954

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +QP    +I  ++ T  L + +A   D+G Y C   N AG A C +  V+  P       
Sbjct: 4955 IQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEP------- 5007

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                    PP   + L    V+EG+ ++ SC + G     +QW K  + IKPS     S 
Sbjct: 5008 ------KKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSF 5061

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA---------- 4723
             +    L + +    D GDY C A N AG  T   K KVT  D+    PA          
Sbjct: 5062 ASGTAVLELRDVAKADSGDYVCKASNVAGSDT--TKSKVTIKDKPAVAPATKKAAVDGRL 5119

Query: 4724 --LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE-GNNAVLLI 4780
              ++  + I V E   A F  ++     P ++W +             IH+ G+ A L I
Sbjct: 5120 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEI 5179

Query: 4781 GNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +T + D+G + C A    G++E++  L V  +
Sbjct: 5180 RDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 5212



 Score =  153 bits (371), Expect = 2e-35
 Identities = 107/413 (25%), Positives = 195/413 (47%), Gaps = 26/413 (6%)

Query: 4400 VVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI 4459
            + E  V   +PP F + ++       E A  + + DG P   I WY+E+  ++++P +++
Sbjct: 3674 ICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKM 3733

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
               +  + L+I +V   D   ++  A+N  G    SA LV++ ++       +PP F   
Sbjct: 3734 QFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK-------LPPFFARK 3786

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             ++V+ T G  V  + ++ G++P+ V W K+G  ++ D   +        TL IL+    
Sbjct: 3787 LKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQS 3846

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQ 4638
              G+Y C A N  G A   A+ ++S                 PP   ++P+   + A G+
Sbjct: 3847 HIGQYNCSASNPLGTASSSAKLILS-------------EHEVPPFFDLKPVSVDL-ALGE 3892

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            +  F C + G     + W K ++ I+P   ++M+   +  TL + +    D G Y C A 
Sbjct: 3893 SGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYAS 3952

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
            N AG+ + +A+L V +P +   +  L P R  +V + +  +++ +I    +  + W ++ 
Sbjct: 3953 NIAGKDSCSAQLGVQEPPRF--IKKLEPSR--IVKQDEFTRYECKIGGSPEIKVLWYKDE 4008

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              I E+  F+M    + AVL + N   ED+G +TC A  AAG   +S  L VK
Sbjct: 4009 TEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 4061



 Score =  153 bits (371), Expect = 2e-35
 Identities = 106/407 (26%), Positives = 184/407 (45%), Gaps = 29/407 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP F K+++P +V   + A  + +  G P   + WY+ +  ++ +  +++H  +  + L
Sbjct: 4624 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 4683

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +  QV + DS  +   AEN  G    S  L V+E++       +PPSF+   ++V  T G
Sbjct: 4684 VFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK-------LPPSFSRQLRDVQETVG 4736

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGK--KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
              V  D  ++G++PI V W K+GK  K  P+++   L  D T TL I +     +G+Y C
Sbjct: 4737 LPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFL--DNTATLNIFKTDRSLAGQYSC 4794

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
             A N  G A   A  ++    T+ K  P      AP        D +V  G++ +F C +
Sbjct: 4795 TATNPIGSASSSARLIL----TEGKNPPFFDIRLAP-------VDAVV--GESADFECHV 4841

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G     V W K  + I+    +Q+S   +   L + +    D G Y C A N  G+ + 
Sbjct: 4842 TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSC 4901

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ--ITSKIKPTIQWLREGALIPET 4764
             A+L + +       P+ T      V E +   FK +  +      T+ W +    I  T
Sbjct: 4902 TAQLNIKERLIP---PSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPT 4958

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             + ++  + N  VL +      D G +TC+ +  AG    ++ +V+K
Sbjct: 4959 SNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 5005



 Score =  151 bits (365), Expect = 8e-35
 Identities = 108/435 (24%), Positives = 193/435 (44%), Gaps = 28/435 (6%)

Query: 4379 TRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438
            T++     + EIE++A     V    V   +PP F  +++P      +    + +  G P
Sbjct: 2714 TKRDAGQYSCEIENEAGRD--VCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTP 2771

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
               + WY+ +  ++ +P+++ +  +  + L+  +V + DS  +   AEN  GTA      
Sbjct: 2772 EITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVF 2831

Query: 4499 VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDI 4558
             ++E++       +PPSF    +++  T G  V L  ++ G+ PI V W ++G  ++   
Sbjct: 2832 RIQERQ-------LPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHE 2884

Query: 4559 RNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKA 4618
              +    D   TL IL+     SG+Y C A N  G A   A        T  +PK     
Sbjct: 2885 NLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSAR------LTAREPK----- 2933

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
              +P   I+P+   ++A G++ +F C + G     + W K +K I+P   + ++   +  
Sbjct: 2934 -KSPFFDIKPVSIDVIA-GESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 2991

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ-ADNLPALTPLRDIVVYEGQP 4737
             LRI +    D G Y C A N  G+   +A+L V +P +    L A       V  +G+ 
Sbjct: 2992 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEA-----SKVAKQGES 3046

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
             Q + +I+   +  + W R  + + E+  + M    + A+L I     ED+G + C A  
Sbjct: 3047 IQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHN 3106

Query: 4798 AAGQVETSAKLVVKS 4812
              G    S  L VK+
Sbjct: 3107 GVGDASCSTALTVKA 3121



 Score =  149 bits (362), Expect = 2e-34
 Identities = 109/429 (25%), Positives = 176/429 (41%), Gaps = 30/429 (6%)

Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
            + T   E  + A T    +E  VK  +PP F ++++P  V ++     E E  G P   +
Sbjct: 1594 SGTYVCEARNDAGTASCSIELKVK--EPPTFIRELKPVEVVKYSDVELECEVTGTPPFEV 1651

Query: 4443 KWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
             W + N  I++S  + +    +   L I +    D+  +  +  N GG+  CS  + ++E
Sbjct: 1652 TWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE 1711

Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                      PPSF    +N            + V G+ PI + WLK+ + +  D    I
Sbjct: 1712 ----------PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYI 1761

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
               D   TL I       SG+Y C A N +G  RC A  +V  PA               
Sbjct: 1762 SFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPA--------------- 1806

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             +I+E  K   V E   +   C + G P   V+W K  K I PS+YF MS   +  + RI
Sbjct: 1807 -QIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRI 1865

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                 +D G Y     N  G  +  A L+V   +   +        D V+  G     + 
Sbjct: 1866 QSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVL--GSSIHMEC 1923

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            +++  +  + QW ++G  I  +  ++++    +  L + N   EDT  +TC+ +  AG  
Sbjct: 1924 KVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDD 1983

Query: 4803 ETSAKLVVK 4811
              S  L VK
Sbjct: 1984 ACSGILTVK 1992



 Score =  148 bits (358), Expect = 6e-34
 Identities = 103/409 (25%), Positives = 173/409 (42%), Gaps = 32/409 (7%)

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
            P+   +PP F +K  P  V       F     G P   + W++ +  +       +    
Sbjct: 4433 PLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLED 4492

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523
            + + L +  V    S  +  +  N  G A C+ +L ++           P  F     + 
Sbjct: 4493 SVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK----------APAKFVKRLNDY 4542

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            ++  G+ + L+   TGT PI V W KNG  V P  R  I   + +  L I  +  +D+G+
Sbjct: 4543 SIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQ 4602

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C   N++G+  C A+ ++                  PP  ++ L+   V+ G +    
Sbjct: 4603 YNCYIENASGKDSCSAQILIL----------------EPPYFVKQLEPVKVSVGDSASLQ 4646

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C++ G P   V WYKGD  ++P+  ++M    +  TL  ++    D G+Y C A NS G 
Sbjct: 4647 CQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGE 4706

Query: 4704 VTVAAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            V+ +  L V    Q   LP      LRD+    G P  F   I+     ++ W ++G  +
Sbjct: 4707 VSASTFLTV----QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPL 4762

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             ++P+ Q     N A L I  T     G ++C AT   G   +SA+L++
Sbjct: 4763 KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 4811



 Score =  145 bits (352), Expect = 3e-33
 Identities = 104/403 (25%), Positives = 173/403 (42%), Gaps = 28/403 (6%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP F K+ +P  V   +   F     G P   + W+R    +       I+   T + L
Sbjct: 2556 EPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAEL 2615

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             +  + +  S  +  V  N  G A C+  L V+E          P +F     + +V  G
Sbjct: 2616 ELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE----------PAAFLKRLSDHSVEPG 2665

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L++  TGT PI V W K+G  +    +  I+  + T  L IL +  +D+G+Y C  
Sbjct: 2666 KSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEI 2725

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG   C A     L +T + P   T+        +EPL+    A G ++   C++ G
Sbjct: 2726 ENEAGRDVCGA-----LVSTLEPPYFVTE--------LEPLE---AAVGDSVSLQCQVAG 2769

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P  TV WYKGD  ++P+  ++   T +  TL  ++    D G+Y C A NS G  +   
Sbjct: 2770 TPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT 2829

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
              ++ +     +      L+DI    G P     ++       + W R+G L+ +  + Q
Sbjct: 2830 VFRIQERQLPPSF--ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQ 2887

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                 N A L I  T    +G ++C A+   G   +SA+L  +
Sbjct: 2888 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 2930



 Score =  144 bits (350), Expect = 5e-33
 Identities = 107/405 (26%), Positives = 172/405 (42%), Gaps = 31/405 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDG-EPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            PP F +K++           FE   +G EPL  + WY++   +K+  + Q       + L
Sbjct: 3780 PPFFARKLKDVHETLGFPVAFECRINGSEPLQ-VSWYKDGVLLKDDANLQTSFVHNVATL 3838

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I Q        +   A N  GTA  SA L++ E         VPP F L   +V++  G
Sbjct: 3839 QILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE-------VPPFFDLKPVSVDLALG 3891

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            +       VTGT PI + W K+ ++++P    K+   + T TL +L+    D+G+Y C A
Sbjct: 3892 ESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYA 3951

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIVAEGQAIEFSCKIV 4647
             N AG+  C A+  V                  PP  I+ L+  +IV + +   + CKI 
Sbjct: 3952 SNIAGKDSCSAQLGVQ----------------EPPRFIKKLEPSRIVKQDEFTRYECKIG 3995

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P   V WYK +  I+ S  F+MS       L +     ED GDY C A+N+AG  + +
Sbjct: 3996 GSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSS 4055

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              LKV +P      P       I   +G     + ++       + W ++   +     +
Sbjct: 4056 TSLKVKEPPIFRKKP-----HPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKY 4110

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +++ E     + I N    D G + C+AT   G       + +K+
Sbjct: 4111 KIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA 4155



 Score =  141 bits (342), Expect = 5e-32
 Identities = 96/404 (23%), Positives = 163/404 (40%), Gaps = 31/404 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP FT+K++            E +  G P   + W+ E   I +   +Q         L 
Sbjct: 4346 PPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALT 4405

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  +   DS  +  +A N  G+ +CSA L V E          PPSF      ++V +G 
Sbjct: 4406 VNMLEESDSGDYTCIATNMAGSDECSAPLTVRE----------PPSFVQKPDPMDVLTGT 4455

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V   + V GT P  V W K   ++ P  R  +  ED    L + +     SG+Y C+  
Sbjct: 4456 NVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVS 4515

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+A C     +  PA                + ++ L D  + +G+ +       G 
Sbjct: 4516 NEAGKASCTTHLYIKAPA----------------KFVKRLNDYSIEKGKPLILEGTFTGT 4559

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P  +V W K    + PS+   ++ T     L I  +  ED G Y C   N++G+ + +A+
Sbjct: 4560 PPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIENASGKDSCSAQ 4619

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            + + +P        +  L  + V  G  A  + Q+    +  + W +    +  T  ++M
Sbjct: 4620 ILILEPPYF-----VKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKM 4674

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                N A L+       D+G + C+A  + G+V  S  L V+ +
Sbjct: 4675 HFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 4718



 Score =  140 bits (338), Expect = 1e-31
 Identities = 101/395 (25%), Positives = 173/395 (43%), Gaps = 36/395 (9%)

Query: 4409 KPPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP F KK+ P  +    E AR   +  G P+  + W++ N  +  S   +++  ++++I
Sbjct: 400  EPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 459

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I  V VEDS  ++  A N  G+  CS  +V++E          PPSF  T +  ++  
Sbjct: 460  LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE----------PPSFIKTLEPADIVR 509

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G    L  +V+GT P ++ W K+ K+++   + ++  +     L I      D G+YECV
Sbjct: 510  GTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECV 569

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              N  G+  C A                T     PP  ++ + D I   GQ +     + 
Sbjct: 570  VANEVGKCGCMA----------------THLLKEPPTFVKKVDDLIALGGQTVTLQAAVR 613

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G    +V W KG ++I+     +MS +     L I +      G Y C+A N AG  T  
Sbjct: 614  GSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSV 673

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI--TSKIKPTIQWLREGALIPETP 4765
             +L V +P +      L     I V  G PA  +  +  T ++KP  +W ++G  +  + 
Sbjct: 674  GELIVKEPAKIIERAEL-----IQVTAGDPATLEYTVAGTPELKP--KWYKDGRPLVASK 726

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +++  + N A L   +    D+G +T   +   G
Sbjct: 727  KYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVG 761



 Score =  136 bits (329), Expect = 2e-30
 Identities = 100/408 (24%), Positives = 176/408 (43%), Gaps = 33/408 (8%)

Query: 4409 KPPIFTKKMQPCRVFEHEQ-ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP F KK++P R+ + ++  R+E +  G P   + WY++   I+ S  F++    + ++
Sbjct: 3968 EPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAV 4027

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L +  + VEDS  +   A N  G+A  S +L V+E          PP F      +    
Sbjct: 4028 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE----------PPIFRKKPHPIETLK 4077

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G  V L+ ++ GT P  V W K+ ++++   + KI+ E+   ++ IL     D G+Y+C 
Sbjct: 4078 GADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCK 4137

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N  G       CV S+            A  APP  ++ L D     G+ ++    I 
Sbjct: 4138 ATNDVG----SDTCVGSI------------ALKAPPRFVKKLSDISTVVGKEVQLQTTIE 4181

Query: 4648 GKPLPTVQWYKG-DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G    +V W+K   ++++ S    +S + +  TL+ S   P + G Y C   N AG    
Sbjct: 4182 GAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQEC 4241

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
             A L V +P      P       I V  G     +  +    + + +W ++G  +     
Sbjct: 4242 FATLSVLEPATIVEKP-----ESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNK 4296

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            +++      + L I N    D+G ++       G+   +A L V  +T
Sbjct: 4297 YKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT 4344



 Score =  136 bits (328), Expect = 2e-30
 Identities = 98/403 (24%), Positives = 169/403 (41%), Gaps = 29/403 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP F ++++                +G     + WYR+   +++  + Q       + L 
Sbjct: 2839 PPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLK 2898

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q  +  S  ++  A N  GTA  SA L   E ++        P F +   +++V +G+
Sbjct: 2899 ILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKS-------PFFDIKPVSIDVIAGE 2951

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
                +  VTG +P+ + W K+ K+++P     I     T  L IL+    DSG+Y C A 
Sbjct: 2952 SADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQAT 3011

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIVAEGQAIEFSCKIVG 4648
            N  G+  C A+  V                  PP+ ++ L+  K+  +G++I+  CKI G
Sbjct: 3012 NDVGKDMCSAQLSVK----------------EPPKFVKKLEASKVAKQGESIQLECKISG 3055

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P   V W++ D  +  S  + MS       L I+EA  ED GDY C A+N  G  + + 
Sbjct: 3056 SPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCST 3115

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V  P      P+      +   +G     + +I+      + W+++   +  +  F+
Sbjct: 3116 ALTVKAPPVFTQKPS-----PVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFK 3170

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +  +  L I N    D G + C+AT   G    S  +  K
Sbjct: 3171 ITSKHFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFK 3213



 Score =  133 bits (322), Expect = 1e-29
 Identities = 92/321 (28%), Positives = 155/321 (48%), Gaps = 24/321 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVE--FDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            PP FTK++    V E E   F++E    G     + WY+ N  I+ + + +I   +   +
Sbjct: 4913 PPSFTKRLSET-VEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 4971

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L +R+  + D+ ++     N  G+A C++++V++E ++       PP F      V V+ 
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKK-------PPVFDQHLTPVTVSE 5024

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+ V+L   V G++PI + WLK G++++P  R       GT  L + +    DSG Y C 
Sbjct: 5025 GEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCK 5084

Query: 4588 AINSAGEARCDAECVVSLPATKDKPK--PQTKAANAPPEII---EPLKDKIVAEGQAIEF 4642
            A N AG     ++  +     KDKP   P TK A     +    EP   ++V +  A  F
Sbjct: 5085 ASNVAGSDTTKSKVTI-----KDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTAT-F 5138

Query: 4643 SCKIVGKPLPTVQWYKGD--KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
              K+ G P+P V+W KG   +L +  + F + +  DE  L I +    D G Y+CVA+N 
Sbjct: 5139 IAKVGGDPIPNVKWTKGKWRQLNQGGRVF-IHQKGDEAKLEIRDTTKTDSGLYRCVAFNE 5197

Query: 4701 AGRVTVAAKLKVTQPDQADNL 4721
             G +     L+V +  + + +
Sbjct: 5198 HGEIESNVNLQVDERKKQEKI 5218



 Score =  132 bits (319), Expect = 3e-29
 Identities = 101/403 (25%), Positives = 163/403 (40%), Gaps = 27/403 (6%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P   T++     V + + A  +V+F G      KW+++   +     ++I    T SIL
Sbjct: 1242 EPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSIL 1301

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I     +DS  +    +N  G + C A + V +        I+PPSFT   + ++   G
Sbjct: 1302 KIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDL-------IIPPSFTKKLKKMDSIKG 1354

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+  V G+ PI + W K+ +++    + K    D T  L I +    DSG Y C A
Sbjct: 1355 SFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSA 1414

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG  +C     V                  PP  +E  + + V     ++    + G
Sbjct: 1415 TNKAGHNQCSGHLTV----------------KEPPYFVEKPQSQDVNPNTRVQLKALVGG 1458

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
                T++W+K +K +       + +     +L +  A   D G Y C   N  G  T  A
Sbjct: 1459 TAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKA 1518

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P Q    P  +P+  +V+  GQ   F+ QIT   K  + W  +G  I       
Sbjct: 1519 TLFVKEPPQFIKKP--SPV--LVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHG 1574

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +      A   I     E++GT+ C A   AG    S +L VK
Sbjct: 1575 ISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 1617



 Score =  132 bits (318), Expect = 4e-29
 Identities = 100/408 (24%), Positives = 172/408 (42%), Gaps = 32/408 (7%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V  + PP F  + +    F  + A+F     G P+    W ++   +  SP+++I     
Sbjct: 210  VTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAEN 269

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
            K IL +  + ++D  V++  A N+ G   C A L++ +K          P F    + V 
Sbjct: 270  KHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK----------PHFIKELEPVQ 319

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
                + V L+ +V   + + V W K+G+K+ P    KI  ED   TL I  A  +DSG Y
Sbjct: 320  SAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTY 379

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK-IVAEGQAIEFS 4643
             C A N AG + C A                T     PP  ++ +    ++  G++    
Sbjct: 380  VCTASNEAGSSSCSA----------------TVTVREPPSFVKKVDPSYLMLPGESARLH 423

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            CK+ G P+  V W+K +K +  S   +M     E  L I++   ED G Y C A N  G 
Sbjct: 424  CKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGS 483

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             + + ++ + +P     +  L P  DIV   G  A  + +++      I W ++   I  
Sbjct: 484  DSCSTEIVIKEPPSF--IKTLEP-ADIV--RGTNALLQCEVSGTGPFEISWFKDKKQIRS 538

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +++  + +   L I +    D G + C      G+    A  ++K
Sbjct: 539  SKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLK 586



 Score =  132 bits (318), Expect = 4e-29
 Identities = 108/405 (26%), Positives = 166/405 (40%), Gaps = 29/405 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P  F K++    V        E  + G P   + W ++ + I  S    I      +IL
Sbjct: 3590 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTIL 3649

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +  +ED A ++ + EN  G   C A + V E          PP F    ++V    G
Sbjct: 3650 EILESTIEDYAQYSCLIENEAGQDICEALVSVLE----------PPYFIEPLEHVEAVIG 3699

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            +   L  KV GT  I + W K   K++     K+  ++   +L+I +    D G+Y C A
Sbjct: 3700 EPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKA 3759

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             NS G     A  V+             KA   PP     LKD     G  + F C+I G
Sbjct: 3760 DNSVGAVASSAVLVI-------------KARKLPPFFARKLKDVHETLGFPVAFECRING 3806

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
                 V WYK   L+K     Q S   +  TL+I +      G Y C A N  G  + +A
Sbjct: 3807 SEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSA 3866

Query: 4709 KLKVTQPDQADNLPALTPLRDIVV--YEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
            KL +++ +    +P    L+ + V    G+   FK  +T      I W ++   I    +
Sbjct: 3867 KLILSEHE----VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGN 3922

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            ++M    N A L +    + D G +TC A+  AG+   SA+L V+
Sbjct: 3923 YKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 3967



 Score =  129 bits (311), Expect = 3e-28
 Identities = 107/421 (25%), Positives = 176/421 (41%), Gaps = 29/421 (6%)

Query: 4391 EHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP 4450
            E++A +Q  V E  VK  +P    ++ +  +V   + A  E    G P    KWY++  P
Sbjct: 664  ENEAGSQTSVGELIVK--EPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 721

Query: 4451 IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG 4510
            +  S  ++I   +  + L      + DS  +     N  G++ C     V ++       
Sbjct: 722  LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRD------ 775

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             + P FT   +NV+       RLD K+ G+ P+ V W K+GK++    R +I   +GT +
Sbjct: 776  -IAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L I+     D+G + C A NS G        +V                  PP  +    
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV----------------QEPPSFVTKPG 878

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
             K V  G A+       G    T++W+KG+K +       +++ A E +L +      D 
Sbjct: 879  SKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDS 938

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G Y C   N AG V  +A L V +P  A  +  L P +  ++ +G   Q   ++T     
Sbjct: 939  GTYTCKVSNVAGGVECSANLFVKEP--ATFVEKLEPSQ--LLKKGDATQLACKVTGTPPI 994

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             I W      I E+   +M    + AVL + +   ED+G + C A   AG    S+ ++V
Sbjct: 995  KITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV 1054

Query: 4811 K 4811
            K
Sbjct: 1055 K 1055



 Score =  128 bits (310), Expect = 4e-28
 Identities = 102/414 (24%), Positives = 165/414 (39%), Gaps = 29/414 (7%)

Query: 4407 PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS 4466
            P  PP     +Q     E + ARF+    G  L  + WY ++  IK S  F++  F    
Sbjct: 6    PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTY 64

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGI---------VPPSFT 4517
             L I + + ED   +  VA N  G    +ANL +E         I           P   
Sbjct: 65   QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIK 124

Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577
               + + V  G L +   ++     +   W K G+++    +  I       +L IL   
Sbjct: 125  RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQ 184

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
              D G+Y C A N  G   C A   V            T+A   PP  +   K      G
Sbjct: 185  VVDCGEYTCKASNEYGSVSCTATLTV------------TEAY--PPTFLSRPKSLTTFVG 230

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
            +A +F C + G P+    W K    + PS  +++S   +++ L +S    +D G Y C A
Sbjct: 231  KAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKA 290

Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
             N  G     A+L +   D+   +  L P++  +    +    + Q+    K T+ W ++
Sbjct: 291  SNKFGADICQAELIII--DKPHFIKELEPVQSAI---NKKVHLECQVDEDRKVTVTWSKD 345

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G  +P   D+++  E   A L I     +D+GT+ C A+  AG    SA + V+
Sbjct: 346  GQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVR 399



 Score =  128 bits (308), Expect = 6e-28
 Identities = 99/410 (24%), Positives = 170/410 (41%), Gaps = 32/410 (7%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
            G +   +PP F +K Q   V  + + + +    G     IKW+++N  + +     +   
Sbjct: 1425 GHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKD 1484

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
             T + L +      DS  +     N  GTA   A L V+E          PP F      
Sbjct: 1485 DTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE----------PPQFIKKPSP 1534

Query: 4523 VNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            V V  +GQ    + ++TGT  I V W  +G ++    ++ I   DG  T  I  A  ++S
Sbjct: 1535 VLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENS 1594

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G Y C A N AG A C  E  V                  PP  I  LK   V +   +E
Sbjct: 1595 GTYVCEARNDAGTASCSIELKVK----------------EPPTFIRELKPVEVVKYSDVE 1638

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
              C++ G P   V W K ++ I+ SK + ++     + L I++  P D G+Y+C+  N  
Sbjct: 1639 LECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEG 1698

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            G  + + ++ + +P        +  + +        A F++ +      +I WL++  ++
Sbjct: 1699 GSCSCSTRVALKEPPS-----FIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQIL 1753

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             E  +  +    + A L I +     +G +TC+A   +G     A L+V+
Sbjct: 1754 DEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 1803



 Score =  125 bits (302), Expect = 3e-27
 Identities = 93/402 (23%), Positives = 163/402 (40%), Gaps = 32/402 (7%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F K+++P +   +++   E + D +    + W ++   +    D++I      + L I
Sbjct: 309  PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEI 368

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ-NVNVTSGQ 4529
                ++DS  +   A N  G++ CSA + V E          PPSF      +  +  G+
Sbjct: 369  PLAKLKDSGTYVCTASNEAGSSSCSATVTVRE----------PPSFVKKVDPSYLMLPGE 418

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
              RL  K+ G+  I V W KN K++      ++   +    L I +   +DSG Y C A+
Sbjct: 419  SARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAV 478

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N  G   C  E V+                  PP  I+ L+   +  G      C++ G 
Sbjct: 479  NDVGSDSCSTEIVIK----------------EPPSFIKTLEPADIVRGTNALLQCEVSGT 522

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
                + W+K  K I+ SK +++        L I      D G+Y+CV  N  G+    A 
Sbjct: 523  GPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMAT 582

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
              + +P        +  + D++   GQ    +  +      ++ W++   +I E    +M
Sbjct: 583  HLLKEPPTF-----VKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKM 637

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                  AVL+I +      G +TC A   AG   +  +L+VK
Sbjct: 638  SFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVK 679



 Score =  125 bits (301), Expect = 5e-27
 Identities = 108/408 (26%), Positives = 166/408 (40%), Gaps = 35/408 (8%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            +P K P F  K     V   E A FE    G     I W ++N  I+   ++ I      
Sbjct: 2931 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNT 2990

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
              L I +V   DS  +   A N  G   CSA L V+E          PP F    +   V
Sbjct: 2991 PHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE----------PPKFVKKLEASKV 3040

Query: 4526 TS-GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
               G+ ++L+ K++G+  I V W +N  ++    +  +   +    L I EA  +DSG Y
Sbjct: 3041 AKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDY 3100

Query: 4585 ECVAINSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
             C A N  G+A C     V  P     KP P           +  LK      G  +   
Sbjct: 3101 ICEAHNGVGDASCSTALTVKAPPVFTQKPSP-----------VGALK------GSDVILQ 3143

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C+I G P   V W K  K ++ SK F+++    +  L I      D G+Y C A N  G 
Sbjct: 3144 CEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVGS 3203

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE-GALIP 4762
             T +  +K  +P +      +  L D     G   + +  +      ++ WL++ G +I 
Sbjct: 3204 DTCSCSVKFKEPPR-----FVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIR 3258

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            E+ + ++    N A L +G+    ++G + C+    AG  E SA L V
Sbjct: 3259 ESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 3306



 Score =  125 bits (301), Expect = 5e-27
 Identities = 101/395 (25%), Positives = 168/395 (42%), Gaps = 32/395 (8%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P    +K +P  V        E    G P    KW+++   +       I   +  + L
Sbjct: 3308 EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASL 3367

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I    + D  +++   +N  G + C+ ++ V ++       IVPPSF    ++VN   G
Sbjct: 3368 KIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDR-------IVPPSFIRKLKDVNAILG 3420

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
              V L+ +V+G+ PI V W ++G ++   P  ++   E   T  L +LE  P D+G Y C
Sbjct: 3421 ASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLE--PSDTGIYTC 3478

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VA N AG   C A   V  P + +    QT      P+ +E      V  G ++ F+  I
Sbjct: 3479 VAANVAGSDECSAVLTVQEPPSFE----QT------PDSVE------VLPGMSLTFTSVI 3522

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G P   V+W+KG + + P +   +S       L + E  P + GDY C+  N AG  + 
Sbjct: 3523 RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASC 3582

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V +P        +  L D  V  G P   +   T     ++ W+++  LI ++  
Sbjct: 3583 TTHLFVKEP-----ATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSER 3637

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              +     + +L I  +  ED   ++C     AGQ
Sbjct: 3638 CSITMTEKSTILEILESTIEDYAQYSCLIENEAGQ 3672



 Score =  124 bits (298), Expect = 1e-26
 Identities = 93/408 (22%), Positives = 177/408 (43%), Gaps = 33/408 (8%)

Query: 4408 SKPPIFTKKMQPCRVFEH-EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS 4466
            ++PP F KK++  ++ +  + +R E +  G P   + W+R    +  S  +++    + +
Sbjct: 2085 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 2144

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
            ++ +  +  EDS  F   A+N  G+  CS  ++V+E          PP F+     V   
Sbjct: 2145 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE----------PPVFSSFPPIVETL 2194

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
                V L+ +++GT P +V W K+ ++++   + KI  ++   ++ IL     D G+Y C
Sbjct: 2195 KNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHC 2254

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
             A N  G   C   C V L                PP  +  L    V  G+  E    I
Sbjct: 2255 KAQNEVGSDTC--VCTVKL--------------KEPPRFVSKLNSLTVVAGEPAELQASI 2298

Query: 4647 VGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             G     VQW K  +++I+ S+  +++   +  TL+ ++A P + G Y C   N  G   
Sbjct: 2299 EGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRE 2358

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
              A L V +P  A  +    P+    V  G+    + ++    + +++W ++G L+  + 
Sbjct: 2359 NMATLMVLEP--AVIVEKAGPM---TVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQ 2413

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              +       + L I +   +D GT+T +     G+   +A + V  +
Sbjct: 2414 KHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDR 2461



 Score =  123 bits (297), Expect = 1e-26
 Identities = 85/309 (27%), Positives = 144/309 (46%), Gaps = 13/309 (4%)

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            + PP+     Q+   + GQ  R   +V+GT  + V W    KK++P    ++ + + TY 
Sbjct: 7    VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQ 65

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT------KDKPKPQTKAANAPPE 4624
            L I EAYP+D G Y  VA N+ G+    A   +  P +      + + + + KAA     
Sbjct: 66   LEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKR 125

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
             IEPL+   VA G   +F+C+I   P    QW+K  + I  S    +  +    +L I  
Sbjct: 126  KIEPLE---VALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR 182

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQI 4744
                D G+Y C A N  G V+  A L VT+   A     L+  + +  + G+ A+F   +
Sbjct: 183  TQVVDCGEYTCKASNEYGSVSCTATLTVTE---AYPPTFLSRPKSLTTFVGKAAKFICTV 239

Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
            T        W ++GA +  +P++++    N  +L + N   +D G ++C+A+   G    
Sbjct: 240  TGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADIC 299

Query: 4805 SAKLVVKSK 4813
             A+L++  K
Sbjct: 300  QAELIIIDK 308



 Score =  123 bits (296), Expect = 2e-26
 Identities = 94/405 (23%), Positives = 169/405 (41%), Gaps = 31/405 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P    +K +   V E +    E    G P   +KW ++   I  S  F +   +  +  
Sbjct: 1804 EPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASF 1863

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I+ V  +DS  +    EN  G++ C A L V ++        +PPSFT     ++   G
Sbjct: 1864 RIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQN-------IPPSFTKKLTKMDKVLG 1916

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + ++ KV+G+ PI   W K+GK++    + +++  + + +L +     +D+  Y C  
Sbjct: 1917 SSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKV 1976

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG+  C     V  P               P  +++P + + + +   +EF   + G
Sbjct: 1977 SNVAGDDACSGILTVKEP---------------PSFLVKPGRQQAIPD-STVEFKAILKG 2020

Query: 4649 KPLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             P   ++W+K D +L+   K F +        L +        G Y C   N  G  +  
Sbjct: 2021 TPPFKIKWFKDDVELVSGPKCF-IGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCT 2079

Query: 4708 AKLKVTQPDQ-ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
              L VT+P +    L A       +V  G  ++ + +I    +  + W R    +P +  
Sbjct: 2080 TMLLVTEPPKFVKKLEA-----SKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDK 2134

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            ++M    + AV+ + N   ED+G F C A   AG    S K++VK
Sbjct: 2135 YRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 2179



 Score =  123 bits (296), Expect = 2e-26
 Identities = 151/713 (21%), Positives = 268/713 (37%), Gaps = 57/713 (7%)

Query: 4105 SKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DG 4163
            S+   PP F   P +V +  GE   F C VTG    ++ W  +   I  G  YK+T  + 
Sbjct: 3871 SEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN 3930

Query: 4164 MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQ 4223
                 + K  + D G+                 L V    +  R + K  P         
Sbjct: 3931 TATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGV---QEPPRFIKKLEP--------- 3978

Query: 4224 YQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE 4283
                     +  ++ +  + +  I   PE+K    K+ ETE Q+S K + +      + E
Sbjct: 3979 --------SRIVKQDEFTRYECKIGGSPEIKVLWYKD-ETEIQESSKFRMSFVDSVAVLE 4029

Query: 4284 LENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQ 4343
            + N  V          H  A      TS  V +    R + +  +T +  +  ++ ++  
Sbjct: 4030 MHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQG 4089

Query: 4344 KPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQ--ERVV 4401
             P  P         +E+   K+ +   E          + + +  E + KA         
Sbjct: 4090 TP--PFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTC 4147

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG-EPLPLIKWYRENFPI-KNSPDFQI 4459
             G +    PP F KK+        ++ + +   +G EP+ ++ W+++   I + S +  I
Sbjct: 4148 VGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVV-WFKDKGEIVRESDNIWI 4206

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
                  + L   +V   ++  +    +N  G  +C A L V E          P +    
Sbjct: 4207 SYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE----------PATIVEK 4256

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             +++ VT+G    L+  V GT  +   W K+GK++  D + KI   +    L I+   P 
Sbjct: 4257 PESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPS 4316

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            DSG Y     N  G+  C A   VS     D+          PP     LK+     G +
Sbjct: 4317 DSGVYSFEVQNPVGKDSCTASLQVS-----DR--------TVPPSFTRKLKETNGLSGSS 4363

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            +   CK+ G P  +V W+     I   + +Q + T +   L ++     D GDY C+A N
Sbjct: 4364 VVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATN 4423

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
             AG    +A L V +P      P   P+ D++   G    F + +      ++ W +  +
Sbjct: 4424 MAGSDECSAPLTVREPPSFVQKP--DPM-DVLT--GTNVTFTSIVKGTPPFSVSWFKGSS 4478

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +       +  E + A L + +     +G +TC  +  AG+   +  L +K+
Sbjct: 4479 ELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKA 4531



 Score =  122 bits (293), Expect = 4e-26
 Identities = 128/587 (21%), Positives = 240/587 (40%), Gaps = 53/587 (9%)

Query: 4237 ERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLR 4296
            E+  +  + V+   PELK K +K+ +   Q    R  +  + N +     + V+K+    
Sbjct: 1819 EKDPMTLECVVAGTPELKVKWLKDGK---QIVPSRYFSMSFENNVASFRIQSVMKQD--- 1872

Query: 4297 ESTHQYAIPGDKVTSNTVA------KSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDP 4350
               + + +  D  +S+  A      +++   +   L + ++V    +  +      +P  
Sbjct: 1873 SGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPIS 1932

Query: 4351 SESTVHGKEVHV-AKQKQTQKEVVGDKEITR---KITSTETTEIEHKAQTQERVVEGPVK 4406
            ++    GKE+   AK +    E     E+     + T+  T ++ + A   +    G + 
Sbjct: 1933 AQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAG--DDACSGILT 1990

Query: 4407 PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS 4466
              +PP F  K    +        F+    G P   IKW++++  + + P   I    + S
Sbjct: 1991 VKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTS 2050

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVN 4524
             L +  V    +  +     N  G+  C+  L+V E          PP F   L A  + 
Sbjct: 2051 FLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE----------PPKFVKKLEASKI- 2099

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V +G   RL+ K+ G+  I V W +N  ++    + ++   D    + +     +DSG +
Sbjct: 2100 VKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDF 2159

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C A N AG   C  + +V     K+ P       ++ P I+E LK+   AE   +   C
Sbjct: 2160 ICEAQNPAGSTSCSTKVIV-----KEPP-----VFSSFPPIVETLKN---AE---VSLEC 2203

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            ++ G P   V WYK  + ++ SK ++++      ++ I      D G+Y C A N  G  
Sbjct: 2204 ELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSD 2263

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE-GALIPE 4763
            T    +K+ +P +      ++ L  + V  G+PA+ +  I       +QWL+E   +I E
Sbjct: 2264 TCVCTVKLKEPPR-----FVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRE 2318

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + + ++    N A L        + G + C+     G  E  A L+V
Sbjct: 2319 SENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMV 2365



 Score =  120 bits (288), Expect = 2e-25
 Identities = 97/411 (23%), Positives = 171/411 (41%), Gaps = 34/411 (8%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
            G +   +PP F  K     V        +  F G     I+W++ N  + +     I   
Sbjct: 863  GALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKE 922

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            + +S L +  V   DS  +     N  G  +CSANL V+E          P +F    + 
Sbjct: 923  ALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE----------PATFVEKLEP 972

Query: 4523 VNVTS-GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
              +   G   +L  KVTGT PI + W  N ++++   ++++   + T  L + +   +DS
Sbjct: 973  SQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDS 1032

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G+Y C A N AG   C +  +V       K  P       P E+++     ++AE     
Sbjct: 1033 GEYMCEAQNEAGSDHCSSIVIV-------KESPYFTKEFKPIEVLKEYDVMLLAE----- 1080

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
                + G P   + W+K + +++  + ++        +L+I +    D G+Y+C   N  
Sbjct: 1081 ----VAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEV 1136

Query: 4702 GRVTVAAKLKVTQPDQ-ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
            G    +A++ + +P      + + + LR      G  A F+  +   +  T+ WL++   
Sbjct: 1137 GSSICSARVTLREPPSFIKKIESTSSLR------GGTAAFQATLKGSLPITVTWLKDSDE 1190

Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            I E  + +M  E N A L +     +  G + C+A   AG    SA L VK
Sbjct: 1191 ITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK 1241



 Score =  120 bits (288), Expect = 2e-25
 Identities = 102/398 (25%), Positives = 171/398 (42%), Gaps = 38/398 (9%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P +  +K  P  V   E    E +  G P   ++WY++   + +S   +   ++  S L
Sbjct: 2367 EPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSL 2426

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I  V  +D+  +    +N  G + C+A + V ++        VPPSFT   +N     G
Sbjct: 2427 RILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA-------VPPSFTRRLKNTGGVLG 2479

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                L+ KV G+ PI V W     K+    + +    D   TL +      D G Y CVA
Sbjct: 2480 ASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVA 2539

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG   C A   V  P +  K +P            EPL+   V  G+ + F+  I G
Sbjct: 2540 ANVAGSDECRAVLTVQEPPSFVK-EP------------EPLE---VLPGKNVTFTSVIRG 2583

Query: 4649 KPLPTVQWYKGDK-LIKPSK---YFQMSRTADE-YTLRISEAFPEDEGDYKCVAYNSAGR 4703
             P   V W++G + L+K  +   YF+ +    E + + IS++     G+Y CV  N+AG+
Sbjct: 2584 TPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQS-----GEYTCVVSNNAGQ 2638

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             +   +L V +P        L  L D  V  G+    ++  T  +  ++ W ++G  I  
Sbjct: 2639 ASCTTRLFVKEP-----AAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITT 2693

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
            +    ++      +L I N+ + D G ++C     AG+
Sbjct: 2694 SEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGR 2731



 Score =  120 bits (288), Expect = 2e-25
 Identities = 100/404 (24%), Positives = 159/404 (39%), Gaps = 31/404 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+FT+K  P    +      + E  G P   + W ++   ++NS  F+I +    + L 
Sbjct: 3122 PPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLH 3181

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I  +   D   +   A N  G+  CS ++  +E          PP F     + +   G 
Sbjct: 3182 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE----------PPRFVKKLSDTSTLIGD 3231

Query: 4530 LVRLDTKVTGTKPIDVYWLKN-GKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
             V L   V G +PI V WLK+ G+ ++     +I   D   TL +      +SGKY C  
Sbjct: 3232 AVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQI 3291

Query: 4589 INSAGEARCDAECVVSLPA-TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
             N AG   C A   V  PA   +KP+P T                 V  G      C + 
Sbjct: 3292 KNDAGMRECSAVLTVLEPARIIEKPEPMT-----------------VTTGNPFALECVVT 3334

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P  + +W+K  + +       ++      +L+I  A   D+G Y     NS G+    
Sbjct: 3335 GTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT 3394

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              + V+  D+      +  L+D+    G     + +++     ++ W ++G  I   P  
Sbjct: 3395 VSVHVS--DRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKC 3452

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            Q     N   L +      DTG +TC A   AG  E SA L V+
Sbjct: 3453 QSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 3496



 Score =  118 bits (283), Expect = 7e-25
 Identities = 97/404 (24%), Positives = 163/404 (40%), Gaps = 30/404 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP F KK++         A F+    G  LP+ + W +++  I    + ++   +  + 
Sbjct: 1149 EPPSFIKKIESTSSLRGGTAAFQATLKGS-LPITVTWLKDSDEITEDDNIRMTFENNVAS 1207

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L +  + V+    +   A+N  G  +CSA L V+E          P + T  A +++VT 
Sbjct: 1208 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE----------PATITEEAVSIDVTQ 1257

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G    L  K +GTK I   W K+G+++    + KI   D    L I+    +DSG+Y   
Sbjct: 1258 GDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFE 1317

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              N  G + C             K +        PP   + LK     +G  I+  C + 
Sbjct: 1318 VQNDVGRSSC-------------KARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVA 1364

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G    ++QW+K D+ I  S+ ++ S   +   L IS+    D G Y C A N AG    +
Sbjct: 1365 GSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCS 1424

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              L V +P      P     +   V      Q K  +      TI+W ++   +      
Sbjct: 1425 GHLTVKEPPYFVEKP-----QSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAAR 1479

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +  +  +  L +      D+GT+ C+ +   G   + A L VK
Sbjct: 1480 SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 1523



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/402 (25%), Positives = 159/402 (39%), Gaps = 30/402 (7%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FTK+ +P  V +        E  G P   I W+++N  +++   ++         L I
Sbjct: 1058 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQI 1117

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
             +    D+  +     N  G++ CSA + + E          PPSF    ++ +   G  
Sbjct: 1118 LKFVAADAGEYQCRVTNEVGSSICSARVTLRE----------PPSFIKKIESTSSLRGGT 1167

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
                  + G+ PI V WLK+  ++  D   ++  E+   +L +     +  GKY C A N
Sbjct: 1168 AAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKN 1227

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
             AG  RC A   V  PAT                I E      V +G       K  G  
Sbjct: 1228 DAGIQRCSALLSVKEPAT----------------ITEEAVSIDVTQGDPATLQVKFSGTK 1271

Query: 4651 LPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
              T +W+K G +L   SKY ++S T     L+I     +D G+Y     N  GR +  A+
Sbjct: 1272 EITAKWFKDGQELTLGSKY-KISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKAR 1330

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            + V   D          L+ +   +G     +  +      +IQW ++   I  +  ++ 
Sbjct: 1331 INVL--DLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 1388

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                N A L I      D+GT+TC AT  AG  + S  L VK
Sbjct: 1389 SFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 1430



 Score =  115 bits (276), Expect = 5e-24
 Identities = 119/511 (23%), Positives = 203/511 (39%), Gaps = 50/511 (9%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  K      G +   E K+ G+P   VSW  +   +    KY     + T   +
Sbjct: 4346 PPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT--CA 4403

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L +  +   D G+YTC A N  G   CS  +                     + T     
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIV 4463

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF-KVDTFEYRLLREVSFRESITKRYVGESD 249
             GT  ++    + + ++   +  + S  D   +++ F+    +   +   I     G++ 
Sbjct: 4464 KGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYT-CIVSNEAGKAS 4522

Query: 250  VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
                  I       +P K  ++  +  +++G     +   +G P   VTW KNG  +  S
Sbjct: 4523 CTTHLYIK------APAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPS 4576

Query: 310  NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  I T           T+KS       + E P+  +  +G              Q + 
Sbjct: 4577 QRCNITT-----------TEKSP------ILEIPSSTVEDAG--------------QYNC 4605

Query: 370  YITDTQQRET-EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            YI +   +++   +I I E    P FVK  +   V+ G      C++ G P   V+W+  
Sbjct: 4606 YIENASGKDSCSAQILILEP---PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKG 4662

Query: 429  DRQIRDDYNHKILVNESGNHALMITN-VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
            D ++R    +K+  +   N A ++ N V ++DSG   C A N  GE +    L V  +EQ
Sbjct: 4663 DTKLRPTTTYKM--HFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV--QEQ 4718

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
             + P F  +   +    G PVV +    G+    ++W KDG P+  +P ++       +T
Sbjct: 4719 KLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTAT 4778

Query: 548  LDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            L+I +   S A  Y CTA N  GS ++ ARL
Sbjct: 4779 LNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809



 Score =  113 bits (272), Expect = 1e-23
 Identities = 94/404 (23%), Positives = 151/404 (37%), Gaps = 31/404 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP FT++++            E +  G     + W+ E   I +   +Q         L 
Sbjct: 2464 PPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQ 2523

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  +   D   +  VA N  G+ +C A L V+E          PPSF    + + V  G+
Sbjct: 2524 LNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE----------PPSFVKEPEPLEVLPGK 2573

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V   + + GT P  V W +  +++    R  I  ED    L +       SG+Y CV  
Sbjct: 2574 NVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVS 2633

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N+AG+A C     V  PA                  ++ L D  V  G++I       G 
Sbjct: 2634 NNAGQASCTTRLFVKEPAA----------------FLKRLSDHSVEPGKSIILESTYTGT 2677

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
               +V W K    I  S+   +  T     L I  +   D G Y C   N AGR    A 
Sbjct: 2678 LPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGAL 2737

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            +   +P     +  L PL   V   G     + Q+    + T+ W +    +  TP+++ 
Sbjct: 2738 VSTLEPPYF--VTELEPLEAAV---GDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRT 2792

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                N A L+       D+G +TC+A  + G   +     ++ +
Sbjct: 2793 YFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 2836



 Score =  111 bits (268), Expect = 5e-23
 Identities = 83/317 (26%), Positives = 134/317 (42%), Gaps = 19/317 (5%)

Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           PV PP I    +++   EG  A+FQ ++SG    +V+W+   +++  S    +    +  
Sbjct: 6   PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 64

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
            L +      D G YT +A N  G + ++  L++E+P ES + ++             E+
Sbjct: 65  QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAP-ESILHER------------IEQ 111

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            IE+  KA AP   +  +  +V  G + +F C +   P     WF   R+I +     I 
Sbjct: 112 EIEMEMKA-APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR 170

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
            ++  + +L I    + D G  TC A N+ G  +    L V E      P F+ R  +L 
Sbjct: 171 SSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTE---AYPPTFLSRPKSLT 226

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
              G+         GTP     WQKDG  + P+P  RI        L++      D   Y
Sbjct: 227 TFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVY 286

Query: 562 QCTAQNVAGSTATRARL 578
            C A N  G+   +A L
Sbjct: 287 SCKASNKFGADICQAEL 303



 Score =  108 bits (259), Expect = 6e-22
 Identities = 89/314 (28%), Positives = 140/314 (44%), Gaps = 38/314 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP    KP +  +  G+    +    G+    + WFK  + L++     I      ++L 
Sbjct: 870  PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLE 929

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +   + SDSG YT    N     V  G   VE     +V++  + ++         E++E
Sbjct: 930  LYLVKTSDSGTYTCKVSN-----VAGG---VECSANLFVKEPAT-FV---------EKLE 971

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
             S      Q +K        +G  T+  C+VTG P  ++TWF NDR+I++   H++   E
Sbjct: 972  PS------QLLK--------KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVE 1017

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
            S    L +T+V + DSG   C A+N++G     C   VI KE   +P F + F  + V +
Sbjct: 1018 S-TAVLRLTDVGIEDSGEYMCEAQNEAGSD--HCSSIVIVKE---SPYFTKEFKPIEVLK 1071

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
               V+L A   GTP   ITW KD   +    + +        +L I +  A+DA  YQC 
Sbjct: 1072 EYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCR 1131

Query: 565  AQNVAGSTATRARL 578
              N  GS+   AR+
Sbjct: 1132 VTNEVGSSICSARV 1145



 Score =  107 bits (256), Expect = 1e-21
 Identities = 117/513 (22%), Positives = 191/513 (37%), Gaps = 51/513 (9%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  +      G N  F   +RG P   V+W R    LV+ ++ ++ + +   ++ 
Sbjct: 2557 PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELE 2616

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L    I     GEYTC   N  G+A C+  +  +                  S  +E   
Sbjct: 2617 LF--NIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTY 2674

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             GT   +    +        +G + ++++   + T E   + E+    + TKR  G+   
Sbjct: 2675 TGTLPISVTWKK--------DGFNITTSEKCNIVTTEKTCILEIL---NSTKRDAGQYSC 2723

Query: 251  QISTEIDRS-----LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
            +I  E  R      +  + PP    +    +   G     Q Q++G P   V+W+K   +
Sbjct: 2724 EIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTK 2783

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
            L  + ++    T+N  TL       +DSG YT  AEN  G           S T   +Q+
Sbjct: 2784 LRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIG--------TASSKTVFRIQE 2835

Query: 366  QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
            ++       Q ++ E+ +                      G      CR+ G    +V W
Sbjct: 2836 RQLPPSFARQLKDIEQTV----------------------GLPVTLTCRLNGSAPIQVCW 2873

Query: 426  FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
            + +   +RD  N +    ++    L I    LS SG  +C A N  G  +   RL   E 
Sbjct: 2874 YRDGVLLRDHENLQTSFVDN-VATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREP 2932

Query: 486  EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545
            ++  +P F  +  +++V  GE         G    RITW KD   I P     I   G  
Sbjct: 2933 KK--SPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNT 2990

Query: 546  STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              L I +    D+  Y C A N  G     A+L
Sbjct: 2991 PHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 3023



 Score =  102 bits (244), Expect = 4e-20
 Identities = 165/808 (20%), Positives = 292/808 (36%), Gaps = 69/808 (8%)

Query: 67   GEPSPPIFEQIFKNARFA-QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            G   PP F +  + +R   Q    ++E K+ G+P   V W + +  + E +K+ M + + 
Sbjct: 3965 GVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDS 4024

Query: 126  TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET 185
               + +    +   D G+YTC A N  G A  S  ++ +               +     
Sbjct: 4025 VAVLEM--HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVH 4082

Query: 186  VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
            +E +  GT  +     +  +++   +G  +    +  + +     +      E   K   
Sbjct: 4083 LECELQGTPPFHVSWYKDKRELR--SGKKYKIMSENFLTSIHILNVDAADIGEYQCK--- 4137

Query: 246  GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
              +DV   T +  S+   +PP+  +K  +     G + Q Q  + G     V WFK    
Sbjct: 4138 ATNDVGSDTCVG-SIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFK---- 4192

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
                +K EI+             ++SD+  +   +EN    I T  +  VE         
Sbjct: 4193 ----DKGEIV-------------RESDN-IWISYSEN----IATLQFSRVEPANAG---K 4227

Query: 366  QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
               Q   D   +E    + + E A     V+  +   VT G     +C V G P     W
Sbjct: 4228 YTCQIKNDAGMQECFATLSVLEPAT---IVEKPESIKVTTGDTCTLECTVAGTPELSTKW 4284

Query: 426  FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
            F + +++  D  +KI      +  L I NV  SDSGV +   +N  G+ +    L V   
Sbjct: 4285 FKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV--S 4341

Query: 486  EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545
            ++ V P F  +    N   G  VV+  +  G+P   ++W  +G  I    + +       
Sbjct: 4342 DRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT 4401

Query: 546  STLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXX 605
              L +   + SD+  Y C A N+AGS    A L              + +   T V    
Sbjct: 4402 CALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTS 4461

Query: 606  XXXXXXXXYLRHVERARPYIPPGE-----EDRVYPPPQFIVPLKS------VTAMEGGKI 654
                     +   + +   +P        ED V     F V          + + E GK 
Sbjct: 4462 IVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKA 4521

Query: 655  HFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAV 714
               T +  +  P   ++ L N  SIE       I    +     +S+  + +G     + 
Sbjct: 4522 SCTTHLY-IKAPAKFVKRL-NDYSIEKGKPL--ILEGTFTGTPPISVTWKKNGINVTPSQ 4577

Query: 715  SATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIR 774
                    K+ +   P +T+E   Q+     YI+          Q  I E     P F++
Sbjct: 4578 RCNITTTEKSPILEIPSSTVEDAGQYN---CYIENASGKDSCSAQILILEP----PYFVK 4630

Query: 775  PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMH 834
             L+ + ++  G +A  + QL     P + V WYK    +  ++     F     +L    
Sbjct: 4631 QLEPV-KVSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQ 4687

Query: 835  LRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +   D+G Y  +A N +GE  ++  + V
Sbjct: 4688 VDINDSGEYICKAENSVGEVSASTFLTV 4715



 Score =   99 bits (238), Expect = 2e-19
 Identities = 101/463 (21%), Positives = 193/463 (41%), Gaps = 28/463 (6%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            + K+ +   +EC +  S  P +K+ W+ +   +   ++++ +   S   L++ +   EDS
Sbjct: 3981 IVKQDEFTRYECKIGGS--PEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDS 4038

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHP-QGKAGLEAVEQAEEARLAKGRRPS 2902
            G YTC+A N+ GSA++S SL+   +  I+    HP +   G +   + E           
Sbjct: 4039 GDYTCEAHNAAGSASSSTSLKVK-EPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSW 4097

Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLE----GQVEPKNDPDLKIEWYFNGKVLEQGS 2958
              D    +      I +E+ L    +L+++    G+ + K   D+  +       L+   
Sbjct: 4098 YKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP 4157

Query: 2959 RF-KLTSDFGFVTLDLVDVYERDSGIYTCKA--YNKRGEAFTSS-TVYCTSKDNL--IER 3012
            RF K  SD   V    V +     G        +  +GE    S  ++ +  +N+  ++ 
Sbjct: 4158 RFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQF 4217

Query: 3013 TQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFK--DIVDISEGQIAHYEA 3070
            ++      G    Q     ++ + G Q    T    E  T+ +  + + ++ G     E 
Sbjct: 4218 SRVEPANAGKYTCQ-----IKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLEC 4272

Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
            ++  T + S   +WF +GK + + ++ +  +   +  L+I+    +DSG YS    N  G
Sbjct: 4273 TVAGTPELST--KWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVG 4330

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            +   +  L+  D++    P FT  ++   GL  G S   EC V     P + + W+H G 
Sbjct: 4331 KDSCTASLQVSDRT--VPPSFTRKLKETNGL-SGSSVVMECKV--YGSPPISVSWFHEGN 4385

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +    + +T        L +   +  DSG+Y C A N  G D
Sbjct: 4386 EISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSD 4428



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 59/189 (31%), Positives = 89/189 (47%), Gaps = 6/189 (3%)

Query: 388 KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447
           +A  P F+   +      GK  +F C VTG P  E  W  +   +    N +I   E+  
Sbjct: 212 EAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAEN-K 270

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
           H L ++N+T+ D GV +C A NK G    Q  L +I+K     P F++    +     + 
Sbjct: 271 HILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK-----PHFIKELEPVQSAINKK 325

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           V L  +        +TW KDG  + P  + +I  +   +TL+IP AK  D+  Y CTA N
Sbjct: 326 VHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASN 385

Query: 568 VAGSTATRA 576
            AGS++  A
Sbjct: 386 EAGSSSCSA 394



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 109/493 (22%), Positives = 178/493 (36%), Gaps = 50/493 (10%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G     E K+ G P   V W +    L    K+   +  +    SL I  +   D G YT
Sbjct: 2383 GETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS--SLRILSVERQDAGTYT 2440

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHV---SETVEHKAYGTQGYTTEQSR 202
               +N  G++ C+  +                    V   S  +E K  G+   +     
Sbjct: 2441 FQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFH 2500

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262
            +  K+   +G  + +T    V T +   L + S   + T      ++V  S E    L  
Sbjct: 2501 EKTKIV--SGAKYQTTFSDNVCTLQLNSL-DSSDMGNYT---CVAANVAGSDECRAVLTV 2554

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
              PP   ++P   ++  G +  F   + G P  +V WF+  + L+  ++  I        
Sbjct: 2555 QEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 2614

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L + N   S SG YT        C+V++                      +  Q     R
Sbjct: 2615 LELFNIDISQSGEYT--------CVVSN----------------------NAGQASCTTR 2644

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + + E A    F+K   D  V  GK    +   TG     VTW  +   I       I+ 
Sbjct: 2645 LFVKEPAA---FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVT 2701

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
             E     L I N T  D+G  +C   N++G       ++ +E      P FV     L  
Sbjct: 2702 TEK-TCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEP-----PYFVTELEPLEA 2755

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              G+ V L  +  GTP   ++W K    + P PE R +     +TL   +   +D+  Y 
Sbjct: 2756 AVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYT 2815

Query: 563  CTAQNVAGSTATR 575
            C A+N  G+ +++
Sbjct: 2816 CKAENSIGTASSK 2828



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 105/446 (23%), Positives = 183/446 (41%), Gaps = 47/446 (10%)

Query: 54   SSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLV 113
            SS  R  +T G+    +PP F+          G +A FE  + G     VSW +    + 
Sbjct: 4804 SSSARLILTEGK----NPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIR 4859

Query: 114  ECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXX 173
               KY + Y E +  +++L  ++  GD G+YTC A N+ G+  C+  +  +         
Sbjct: 4860 SGGKYQISYLENSAHLTVL--KVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT 4917

Query: 174  XXXXXYRHVSETVEH---KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL 230
                  + +SETVE     ++  +G     S+      Y N  +   T + ++ TF+   
Sbjct: 4918 ------KRLSETVEETEGNSFKLEG-RVAGSQPITVAWYKNNIEIQPTSNCEI-TFKNNT 4969

Query: 231  L----REVSFRES--ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQ 284
            L    R+    ++   T +   ++   + T       P  PP   Q      + EG   Q
Sbjct: 4970 LVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQ 5029

Query: 285  FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPN 344
                + G+   R+ W K G+ +  S++           L +R+  K+DSG Y   A N  
Sbjct: 5030 LSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVA 5089

Query: 345  GCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI-EISEKALAPQFVKVCQDRDV 403
            G   T   + ++          +      T++   + R+  +SE    PQ ++V +    
Sbjct: 5090 GSDTTKSKVTIK---------DKPAVAPATKKAAVDGRLFFVSE----PQSIRVVEKTTA 5136

Query: 404  TEGKMTRFDCRVTGRPYPEVTWFIND-RQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
            T      F  +V G P P V W     RQ+  +   ++ +++ G+ A L I + T +DSG
Sbjct: 5137 T------FIAKVGGDPIPNVKWTKGKWRQL--NQGGRVFIHQKGDEAKLEIRDTTKTDSG 5188

Query: 462  VVTCVARNKSGETAFQCRLNVIEKEQ 487
            +  CVA N+ GE      L V E+++
Sbjct: 5189 LYRCVAFNEHGEIESNVNLQVDERKK 5214



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 110/532 (20%), Positives = 193/532 (36%), Gaps = 55/532 (10%)

Query: 47   QMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWT 106
            Q + ++E+   R  +         PP F    +    A G +   + ++ G P   VSW 
Sbjct: 2720 QYSCEIENEAGRD-VCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWY 2778

Query: 107  RKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGX 166
            +    L    +Y   +       +L+  ++   D GEYTC A N  G A      + +  
Sbjct: 2779 KGDTKLRPTPEYRTYFTNNVA--TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQ-- 2834

Query: 167  XXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT---DHSSTDDFKV 223
                         + + +TV      T       S   Q   Y +G    DH +     V
Sbjct: 2835 -ERQLPPSFARQLKDIEQTVGLPV--TLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFV 2891

Query: 224  DTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLG--PVSPPKIAQKPRNSKLQEGA 281
            D      + +     S        + +  ++   R     P   P    KP +  +  G 
Sbjct: 2892 DNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGE 2951

Query: 282  DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAE 341
             A F+  ++G    R+TW K+                        N +    G+YT+   
Sbjct: 2952 SADFECHVTGAQPMRITWSKD------------------------NKEIRPGGNYTIT-- 2985

Query: 342  NPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDR 401
                C+  + +L +    +        Q   D  +     ++ + E    P+FVK  +  
Sbjct: 2986 ----CVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP---PKFVKKLEAS 3038

Query: 402  DVT-EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHALMITNVTLSD 459
             V  +G+  + +C+++G P  +V+WF ND ++ + + + +  +N      L I   +  D
Sbjct: 3039 KVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVA--LLTINEASAED 3096

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519
            SG   C A N  G+ +    L V        P F ++ S +   +G  V+L     GTP 
Sbjct: 3097 SGDYICEAHNGVGDASCSTALTV-----KAPPVFTQKPSPVGALKGSDVILQCEISGTPP 3151

Query: 520  PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              + W KD   +  + + +I +    + L I   +ASD   Y C A N  GS
Sbjct: 3152 FEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVGS 3203



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 4/171 (2%)

Query: 402  DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
            D   G+   F+C VTG    +V+W  + R+IR    ++I   E+  H L +  V   DSG
Sbjct: 4828 DAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAH-LTVLKVDKGDSG 4886

Query: 462  VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTP 520
              TC A N+ G+ +   +LN+  KE+++ P F +R S T+   EG    L  R  G+   
Sbjct: 4887 QYTCYAVNEVGKDSCTAQLNI--KERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPI 4944

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             + W K+ + I P     I        L + +A  +DA  Y C   N AGS
Sbjct: 4945 TVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGS 4995



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)

Query: 382  RIEISEKALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            ++ I E+ + P F K + +  + TEG   + + RV G     V W+ N+ +I+   N +I
Sbjct: 4904 QLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEI 4963

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
               ++    L +    ++D+G+ TC   N +G     C  +++ KE    P F +  + +
Sbjct: 4964 TF-KNNTLVLQVRKAGMNDAGLYTCKVSNDAGSAL--CTSSIVIKEPKKPPVFDQHLTPV 5020

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             V EGE V L+    G+   RI W K G  I P+         G + L++     +D+  
Sbjct: 5021 TVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGD 5080

Query: 561  YQCTAQNVAGSTATRARL 578
            Y C A NVAGS  T++++
Sbjct: 5081 YVCKASNVAGSDTTKSKV 5098



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 111/512 (21%), Positives = 199/512 (38%), Gaps = 53/512 (10%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F+    +   A G +  F+  + G     ++W +    +     Y M   E T  ++
Sbjct: 3876 PPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLT 3935

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            +L  ++G GD G+YTC A N  G+  CS  +  +                  S  V+   
Sbjct: 3936 VL--KVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKL-------EPSRIVKQDE 3986

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFK---VDTFEYRLLREVSFRESITKRYVGE 247
            +         S + + + Y + T+   +  F+   VD+     +  +S  +S    Y  E
Sbjct: 3987 FTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDS--GDYTCE 4044

Query: 248  S-DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
            + +   S     SL    PP   +KP   +  +GAD   + +L G P   V+W+K+ + L
Sbjct: 4045 AHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKREL 4104

Query: 307  INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ 366
             +  K++I++ +  T++ + N   +D G Y   A N  G     G +A+++P   +V+  
Sbjct: 4105 RSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPR-FVKKL 4163

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
                    ++ + +  IE +E       + V   +D  +G++ R    +         W 
Sbjct: 4164 SDISTVVGKEVQLQTTIEGAEP------ISVVWFKD--KGEIVRESDNI---------WI 4206

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
                 I      ++    +G +   I N    D+G+  C A            L+V+E  
Sbjct: 4207 SYSENIATLQFSRVEPANAGKYTCQIKN----DAGMQECFA-----------TLSVLEPA 4251

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
             +V     E+  ++ V  G+   L     GTP     W KDG  +  + + +I      S
Sbjct: 4252 TIV-----EKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS 4306

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             L I     SD+  Y    QN  G  +  A L
Sbjct: 4307 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASL 4338



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 63/227 (27%), Positives = 100/227 (44%), Gaps = 8/227 (3%)

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            L + SP  S       Q   D   RE    + + E A   + ++  +   VT G     +
Sbjct: 3274 LQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPA---RIIEKPEPMTVTTGNPFALE 3330

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C VTG P     WF + R++  D  H I  +N+  +  L I    +SD G+ +   +N  
Sbjct: 3331 CVVTGTPELSAKWFKDGRELSADSKHHITFINKVAS--LKIPCAEMSDKGLYSFEVKNSV 3388

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G++   C ++V   +++V P F+ +   +N   G  VVL  R  G+    + W +DG  I
Sbjct: 3389 GKS--NCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEI 3446

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +  P+ +        TL++   + SD   Y C A NVAGS    A L
Sbjct: 3447 VSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 3493



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 111/516 (21%), Positives = 193/516 (37%), Gaps = 58/516 (11%)

Query: 71   PPIFEQIFKNARFAQGGNA-KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP F +  + ++  + G++ + E K+ G+P   V W R +  L   +KY M + +    +
Sbjct: 2087 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVI 2146

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
             +    +   D G++ C A+N  G   CS  +  +               ++   ++E +
Sbjct: 2147 QM--NNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECE 2204

Query: 190  AYGTQGYTT------EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
              GT  +         Q R ++K    +   H+S     VDT       ++       + 
Sbjct: 2205 LSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDT------SDIGEYHCKAQN 2258

Query: 244  YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             VG SD  + T     +    PP+   K  +  +  G  A+ Q  + G     V W K  
Sbjct: 2259 EVG-SDTCVCT-----VKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKE- 2311

Query: 304  QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTES-Y 362
                   K E+I             ++S++   T + EN    + T  +   E      Y
Sbjct: 2312 -------KEEVI-------------RESENIRITFV-EN----VATLQFAKAEPANAGKY 2346

Query: 363  VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            +     Q   D   RE    + + E A+    V+      VT G+    +C+V G P   
Sbjct: 2347 I----CQIKNDGGMRENMATLMVLEPAV---IVEKAGPMTVTVGETCTLECKVAGTPELS 2399

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            V W+ + + +     HK       + +L I +V   D+G  T   +N  G+++  C   V
Sbjct: 2400 VEWYKDGKLLTSSQKHKFSFYNKIS-SLRILSVERQDAGTYTFQVQNNVGKSS--CTAVV 2456

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542
               ++ V P F  R        G   +L  +  G+    + W  +   I+   + +    
Sbjct: 2457 DVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFS 2516

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
                TL +    +SD   Y C A NVAGS   RA L
Sbjct: 2517 DNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVL 2552



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 109/510 (21%), Positives = 201/510 (39%), Gaps = 48/510 (9%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  K+     G +   E ++ G+    V W +    +V   K    ++E    ++
Sbjct: 3405 PPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLN 3464

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L + +  P D G YTC A N  G   CS  +  +                 +S T     
Sbjct: 3465 LSLLE--PSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVI 3522

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF--KVDTFEYRLLREVSFRESITKRYVGES 248
             GT  +  +  + ++++     + + S +DF  +++ FE + L    +   +T      +
Sbjct: 3523 RGTPPFKVKWFKGSRELV-PGESCNISLEDFVTELELFEVQPLESGDYSCLVT------N 3575

Query: 249  DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
            D   S      L    P    ++  +  ++ G+    +   +G P   V+W K+ + LI+
Sbjct: 3576 DAG-SASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKD-EYLIS 3633

Query: 309  SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
             ++   IT           T+KS     T+L               +ES  E Y Q    
Sbjct: 3634 QSERCSITM----------TEKS-----TILE-------------ILESTIEDYAQ-YSC 3664

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
                +  Q   E  + + E    P F++  +  +   G+     C+V G P   ++W+  
Sbjct: 3665 LIENEAGQDICEALVSVLEP---PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKE 3721

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
              ++R    +K+   ++   +L+I  V  SD G  +C A N  G  A    L +  K + 
Sbjct: 3722 HTKLRSAPAYKMQF-KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI--KARK 3778

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            + P F  +   ++   G PV    R  G+   +++W KDGV +  +  L+       +TL
Sbjct: 3779 LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATL 3838

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I +   S    Y C+A N  G+ ++ A+L
Sbjct: 3839 QILQTDQSHIGQYNCSASNPLGTASSSAKL 3868



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 57/207 (27%), Positives = 95/207 (45%), Gaps = 6/207 (2%)

Query: 373  DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
            D  +   + RI + +  + P F K  +  D  +G     +C V G     + WF +D++I
Sbjct: 1321 DVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEI 1380

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPK 492
                 +K   +++    L I+ +  +DSG  TC A NK+G    QC  ++  KE    P 
Sbjct: 1381 SASEKYKFSFHDN-TAFLEISQLEGTDSGTYTCSATNKAGHN--QCSGHLTVKEP---PY 1434

Query: 493  FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552
            FVE+  + +V     V L A   GT    I W KD   +       +  D  +++L++  
Sbjct: 1435 FVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFA 1494

Query: 553  AKASDAAWYQCTAQNVAGSTATRARLY 579
            AKA+D+  Y C   N  G+  ++A L+
Sbjct: 1495 AKATDSGTYICQLSNDVGTATSKATLF 1521



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 70/302 (23%), Positives = 126/302 (41%), Gaps = 12/302 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  ++    +GG A F+  L+G+    V+W +    + E +   M +       S
Sbjct: 1150 PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVA--S 1207

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L +  I    +G+Y C A+N  G   CS  +  +               +    T++ K 
Sbjct: 1208 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKF 1267

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDD---FKVDTFEYRLLREVSFRESITKRYVGE 247
             GT+  T +  +  Q++   +    S TD     K+ + E +   E +F     +  VG 
Sbjct: 1268 SGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFE---VQNDVGR 1324

Query: 248  SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307
            S  +    +   L  + PP   +K +     +G+    +  ++G+    + WFK+ Q + 
Sbjct: 1325 SSCKARINV---LDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEIS 1381

Query: 308  NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
             S K++     N   L +   + +DSG YT  A N  G    SG+L V+ P   +V+  +
Sbjct: 1382 ASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEP-PYFVEKPQ 1440

Query: 368  SQ 369
            SQ
Sbjct: 1441 SQ 1442



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 80/333 (24%), Positives = 142/333 (42%), Gaps = 33/333 (9%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP FT    + V+ +EG     E  +   G Q + + W+ N   I+ +      +    +
Sbjct: 4913 PPSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTL 4970

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            VL++      D+G Y+C+ +N  G A  +  +  V K   + P F  H+  +  + +G+ 
Sbjct: 4971 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSI--VIKEPKKPPVFDQHLTPVT-VSEGEY 5027

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P ++I+W   G+ ++ S R       G  VL++      DSG+YVC+A
Sbjct: 5028 VQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKA 5085

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
             N  G D T++ +    K  V          A   +  ++ G               F++
Sbjct: 5086 SNVAGSDTTKSKVTIKDKPAV----------APATKKAAVDGRL------------FFVS 5123

Query: 3287 QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY-NGKKLPHGHRYRTFHDFGIVILDIL 3345
            + Q + ++VE  +A F A++    DP   V+W     ++L  G R           L+I 
Sbjct: 5124 EPQSI-RVVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIR 5180

Query: 3346 YCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
               + +SG Y CVA N+ G   +  NL+   ++
Sbjct: 5181 DTTKTDSGLYRCVAFNEHGEIESNVNLQVDERK 5213



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 79/352 (22%), Positives = 153/352 (43%), Gaps = 36/352 (10%)

Query: 2904 PDTEYPK-PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            PD E P  P  II    +    EGQ    + +V   +  DLK+ WY   K ++    F++
Sbjct: 1    PDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRM 57

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022
            T       L++ + Y  D G YT  A N  G+  +++ +   + ++++         E +
Sbjct: 58   TQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILH--------ERI 109

Query: 3023 EKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVI 3082
            E  Q +E  ++  P  +   +              ++++ G +A +   +      ++  
Sbjct: 110  E--QEIEMEMKAAPVIKRKIEP-------------LEVALGHLAKFTCEI--QSAPNVRF 152

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVD 3142
            +WF  G+ I  S +     +  +  LEIL T+  D G Y+C+A+N++G    +  L    
Sbjct: 153  QWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-- 210

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
             ++   P F +  +++     G++A F CTV     P ++  W  +G  +  S   +   
Sbjct: 211  -TEAYPPTFLSRPKSLTTFV-GKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWRISD 266

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254
                 +L+++     D G Y C+A NK+G D  +A +    K   +++ L+P
Sbjct: 267  AENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPH-FIKELEP 317



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 109/526 (20%), Positives = 194/526 (36%), Gaps = 27/526 (5%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V K+G++I  EC +  S  P +K+ WF N+  L    +Y  +   S   L I     EDS
Sbjct: 3040 VAKQGESIQLECKISGS--PEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDS 3097

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGK-AGLEAVEQAEEARLAKGRRPS 2902
            G Y C+A N  G A+ S +L       ++     P G   G + + Q E +         
Sbjct: 3098 GDYICEAHNGVGDASCSTALTVKAPP-VFTQKPSPVGALKGSDVILQCEISGTPPFEVVW 3156

Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLE----GQVEPKNDPDLKIEWYFNGKVLEQGS 2958
            V D +  +      I ++H      +L+LE    G+   K   ++  +        ++  
Sbjct: 3157 VKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 3216

Query: 2959 RF-KLTSDFGFVTLDLVDVYERDSGIYTCKA--YNKRGEAFTSSTVYCTSKDNLIERTQH 3015
            RF K  SD   +  D V++     G           RGE    S     S  + I   Q 
Sbjct: 3217 RFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQ- 3275

Query: 3016 PKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPT 3075
              G+            ++ + G +         E   + +    ++      +    + T
Sbjct: 3276 -LGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVT 3334

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G   +  +WF +G+ + A  +    +   +  L+I   + +D G YS    N  G++  +
Sbjct: 3335 GTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT 3394

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
            V +   D+     P F   ++++  +  G S   EC V       + + W+ +G  +   
Sbjct: 3395 VSVHVSDRI--VPPSFIRKLKDVNAIL-GASVVLECRV--SGSAPISVGWFQDGNEIVSG 3449

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD 3255
             + ++        L+++  +  D+G Y C A N  G D   A +              PD
Sbjct: 3450 PKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSF---EQTPD 3506

Query: 3256 SLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAH 3301
            S      +E L G      S     PP  +   +   +LV G+S +
Sbjct: 3507 S------VEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCN 3546



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 61/232 (26%), Positives = 101/232 (43%), Gaps = 23/232 (9%)

Query: 1970 DDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            D    V  P    P+++   +EG P   +     V+   ++V WY   + ++    F+ T
Sbjct: 2    DQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMT 58

Query: 2030 YDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQ 2089
                   L+I  AY ED GTY   A NAVG+  +T+++ ++A   +  + ++++      
Sbjct: 59   QFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQE------ 112

Query: 2090 ELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
                      IE E     PV    +  LE +  G  A F C ++  + P++   WF  G
Sbjct: 113  ----------IEMEMKA-APVIKRKIEPLE-VALGHLAKFTCEIQ--SAPNVRFQWFKAG 158

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            ++I    +          +L+IL T   D G Y CKA+N+ G    T TL V
Sbjct: 159  REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 94/406 (23%), Positives = 173/406 (42%), Gaps = 34/406 (8%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF-PIKNSPDFQIHTFSTKSILIIR 4471
            F  + Q  RV E   A F  +  G+P+P +KW +  +  +       IH    ++ L IR
Sbjct: 5121 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIR 5180

Query: 4472 QVFVEDSAVFAAVAENRGGTAKCSANLVVEE-KRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                 DS ++  VA N  G  + + NL V+E K+++   G +      T   +   +G+ 
Sbjct: 5181 DTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPI-LKKGAGEE 5239

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              +D      K +D    +   ++    D R  +   +     L+ ++  +++ + E   
Sbjct: 5240 EEIDIMEL-LKNVDPKEYEKYARMYGITDFRGLLQAFE-----LLKQSQEEETHRLEIEE 5293

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI-V 4647
            I  +     + E +VS          Q  +   P  +I+ ++++ V +     F   I +
Sbjct: 5294 IERSERDEKEFEELVSFIQ-------QRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKI 5346

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
              P   + WYKG + ++PS  F++S   D +TLR+     +D+G+Y+ V     G    +
Sbjct: 5347 NYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLV----CGPHIAS 5402

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            AKL V +P    +      L+D+ + EGQ      Q  S      +W R G ++      
Sbjct: 5403 AKLTVIEPAWERH------LQDVTLKEGQTCTMTVQF-SVPNVKSEWFRNGRILKPQGRH 5455

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +   E     L I +   ED G +TC+       +ETSA+L ++++
Sbjct: 5456 KTEVEHKVHKLTIADVRAEDQGQYTCKYE----DLETSAELRIEAE 5497



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 67/232 (28%), Positives = 98/232 (42%), Gaps = 30/232 (12%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP  IT +QD T   EGQ A F+ R   V   DLKV W+   KK+     +R        
Sbjct: 9    PPAIITPLQD-TVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTY 64

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400
             L+I   Y E+ G Y  VA N +G+ S+ ANL   + E+++ +                 
Sbjct: 65   QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHE----------------- 107

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
                  R +  +E E   APV    +  +E +  G  A F   +     PN++ +W+  G
Sbjct: 108  ------RIEQEIEMEMKAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAG 158

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            + +    +           LEI  T   D GEY C+A N YG    TA++ V
Sbjct: 159  REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 61/228 (26%), Positives = 97/228 (42%), Gaps = 12/228 (5%)

Query: 354 AVESPTESYVQDQRS---QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410
           A+   T+  V+D  S   + + D         I I E    P F+K  +  D+  G    
Sbjct: 458 AILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP---PSFIKTLEPADIVRGTNAL 514

Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470
             C V+G    E++WF + +QIR    ++ L ++     L I +   +D G   CV  N+
Sbjct: 515 LQCEVSGTGPFEISWFKDKKQIRSSKKYR-LFSQKSLVCLEIFSFNSADVGEYECVVANE 573

Query: 471 SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530
            G+    C    + KE    P FV++   L    G+ V L A   G+    +TW K    
Sbjct: 574 VGKCG--CMATHLLKEP---PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEV 628

Query: 531 IIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           I  + ++++    G + L IP  + S    Y C A+N AGS  +   L
Sbjct: 629 IREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGEL 676



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 142/668 (21%), Positives = 245/668 (36%), Gaps = 78/668 (11%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F T    L  +   S   +C++       + V W+     L      +T        
Sbjct: 2743 PPYFVTELEPLEAAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTNNVAT 2800

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L    V   D+G YTCKA N  G A+     +++ R       QLP  F      ++ +E
Sbjct: 2801 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER-------QLPPSF---ARQLKDIE 2850

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
            +T+     +T       P +     +D + + +   +             ++ D  H+G+
Sbjct: 2851 QTVGLPVTLTCRLNGSAPIQ-VCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQ 2909

Query: 3737 -------PFATGSRVHTLND--------FGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
                   P  T S    L          F    + ID I A ++ ++ C  T       T
Sbjct: 2910 YSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVI-AGESADFECHVTGAQPMRIT 2968

Query: 3782 TAK------------ITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTP 3829
             +K            ITC      +   ++ +G SG+   +       D    +  V  P
Sbjct: 2969 WSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 3028

Query: 3830 PKFITQIKSHTV-EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PKF+ ++++  V ++ E ++ EC++     P++++ W+RN   L    +Y   +      
Sbjct: 3029 PKFVKKLEASKVAKQGESIQLECKISGS--PEIKVSWFRNDSELHESWKYNMSFINSVAL 3086

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRG-MKRSEALTQME 3947
            L I    AEDSG+YIC A N  G D + +T    K P +  Q   P G +K S+ + Q E
Sbjct: 3087 LTINEASAEDSGDYICEAHNGVG-DASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCE 3145

Query: 3948 ATIKKYTSEVYLTEDDLYDVDKK---QPPRFVTQIQSQTSLVEMETTKFECQLA-PVGDP 4003
             +       V++ +       KK       F T +    +L   +  ++ C+    VG  
Sbjct: 3146 ISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHI-LNLEASDVGEYHCKATNEVGSD 3204

Query: 4004 NMKVEWFFNGKPLLHK---NRFTPIYDF--------GYVAMNFGWVYPEDSGEYLCRATN 4052
                   F   P   K   +  T I D         G+  ++  W+  +D GE +  + N
Sbjct: 3205 TCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWL--KDRGEVIRESEN 3262

Query: 4053 LYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQV-TPEQVVEESKARCPP 4111
                          G P      +    +K+   +RE  A   V  P +++E+       
Sbjct: 3263 TRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEK------- 3315

Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIP 4170
                 P+ +TV  G      C VTG P+    W  +G  +   S++ +T+ + +    IP
Sbjct: 3316 -----PEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIP 3370

Query: 4171 KTRQYDTG 4178
                 D G
Sbjct: 3371 CAEMSDKG 3378



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 63/226 (27%), Positives = 100/226 (44%), Gaps = 25/226 (11%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P  IT L   T  SEGQ A ++CR+      +++V WY   K ++    +R +       
Sbjct: 10   PAIITPLQD-TVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ 65

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSR 1963
            L+I   Y ED G YT  A N +GQ  S+  L++++ ESI+    HE   ++I     +  
Sbjct: 66   LEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESIL----HERIEQEI-----EME 116

Query: 1964 YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023
             K A          P   + I+  EV  GH       +   + P +R +W+  GR + + 
Sbjct: 117  MKAA----------PVIKRKIEPLEVALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYES 164

Query: 2024 HRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             +          +L+IL     D G Y CKA+N  G    T+++ V
Sbjct: 165  DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 63/249 (25%), Positives = 104/249 (41%), Gaps = 19/249 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    +    + + +   YE  +   G   + + W+ +   I+ S + R  +   + 
Sbjct: 3969 PPRFIKKLEPSRIVKQDEFTRYECKI--GGSPEIKVLWYKDETEIQESSKFRMSFVDSVA 4026

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            VLE+      DSG Y+C A N  G A  S  L    K K + P F      IE LK G  
Sbjct: 4027 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL----KVK-EPPIFRKKPHPIETLK-GAD 4080

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             H EC +     P   + WY + + +R   + K +S+     + I      D GEY C+A
Sbjct: 4081 VHLECEL--QGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKA 4138

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
             N  G D       C   G + L++  P  + K+ ++ ++ G + Q  +T     P  + 
Sbjct: 4139 TNDVGSD------TCV--GSIALKA-PPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVV 4189

Query: 3287 QIQDVTKLV 3295
              +D  ++V
Sbjct: 4190 WFKDKGEIV 4198



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 65/234 (27%), Positives = 104/234 (44%), Gaps = 29/234 (12%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN--RLTTM 1762
            E+    P    P++D   +E Q A F+ R   V    L+V W      I+ S   R+T  
Sbjct: 4    EMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQF 60

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQ 1822
             D   + +   Y  PED GTYT  A N +G+        V S A+L LE+      ++I+
Sbjct: 61   EDTYQLEIAEAY--PEDEGTYTFVANNAVGQ--------VSSTANLSLEAPESILHERIE 110

Query: 1823 QLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF 1882
            Q           ++E+ +  AP    ++  P +++ G  A + C I+  P  N+R +W+ 
Sbjct: 111  Q-----------EIEMEMKAAPVIKRKIE-PLEVALGHLAKFTCEIQSAP--NVRFQWFK 156

Query: 1883 NGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             G+ +    +    +    ++L+IL     D GEYTCKA N  G    +  L V
Sbjct: 157  AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 67/229 (29%), Positives = 101/229 (44%), Gaps = 26/229 (11%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P  + PL+ T    EGQ A F+ RV   S   + V WY   K+I  +   +         
Sbjct: 10   PAIITPLQDT-VTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ 65

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L+IA    ED G YT VA NA G+   +A++++E   SI        L+E+   IE+   
Sbjct: 66   LEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESI--------LHER---IEQ--- 111

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
                 +IE   K+ PV  + +  P  V+ G      C ++    P +R +WF  GR +  
Sbjct: 112  -----EIEMEMKAAPVIKRKI-EPLEVALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYE 163

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
              +          +L+I+     D GEYT +A N  GS   +A + V E
Sbjct: 164  SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTE 212



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 52/188 (27%), Positives = 79/188 (42%), Gaps = 7/188 (3%)

Query: 392  PQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            PQF+K      V   G+ T F+C++TG P   V+W+++  +I     H I   + G    
Sbjct: 1526 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFID-GLATF 1584

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             I+   + +SG   C ARN +G  +    L V E      P F+     + V +   V L
Sbjct: 1585 QISGARVENSGTYVCEARNDAGTASCSIELKVKEP-----PTFIRELKPVEVVKYSDVEL 1639

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 GTP   +TW K+   I  + +  +        L I +   SD   YQC   N  G
Sbjct: 1640 ECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGG 1699

Query: 571  STATRARL 578
            S +   R+
Sbjct: 1700 SCSCSTRV 1707



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 52/198 (26%), Positives = 92/198 (46%), Gaps = 7/198 (3%)

Query: 382  RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            ++ +SE  + P F       D+  G+   F C VTG    ++TW  ++R+IR   N+K+ 
Sbjct: 3867 KLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMT 3926

Query: 442  VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
            + E+    L +  V   D+G  TC A N +G+ +   +L V E      P+F+++     
Sbjct: 3927 LVEN-TATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEP-----PRFIKKLEPSR 3980

Query: 502  -VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             V++ E      +  G+P  ++ W KD   I  + + R+      + L++      D+  
Sbjct: 3981 IVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGD 4040

Query: 561  YQCTAQNVAGSTATRARL 578
            Y C A N AGS ++   L
Sbjct: 4041 YTCEAHNAAGSASSSTSL 4058



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 66/274 (24%), Positives = 112/274 (40%), Gaps = 9/274 (3%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G +A FE  + G     ++W++    +     Y++     T  + +L  ++G GD G+YT
Sbjct: 2950 GESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRIL--KVGKGDSGQYT 3007

Query: 146  CTARNQYGEAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204
            C A N  G+ +CS  +   E               +  S  +E K  G+        R  
Sbjct: 3008 CQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRND 3067

Query: 205  QKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVS 264
             ++  +   + S  +   + T       +    + I + + G  D   ST    +L   +
Sbjct: 3068 SELHESWKYNMSFINSVALLTINEASAEDSG--DYICEAHNGVGDASCST----ALTVKA 3121

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   QKP      +G+D   Q ++SG P   V W K+ +++ NS K +I + H  T L 
Sbjct: 3122 PPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLH 3181

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            + N + SD G Y   A N  G    S  +  + P
Sbjct: 3182 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEP 3215



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 65/235 (27%), Positives = 101/235 (42%), Gaps = 25/235 (10%)

Query: 2101 EEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT 2160
            ++E P   P  +T L       EG  A F+CRV   +   L + W+   +KI+    +R 
Sbjct: 2    DQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFRM 57

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKI 2220
            T       L+I   Y ED GTY   A N +G+  +T  L +    +I+    H    E+I
Sbjct: 58   TQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESIL----H----ERI 109

Query: 2221 RQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYH 2280
             Q E +       V + KI P            V  G  A F C+++    PN+R +++ 
Sbjct: 110  EQ-EIEMEMKAAPVIKRKIEP----------LEVALGHLAKFTCEIQSA--PNVRFQWFK 156

Query: 2281 NGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
             G+ +  + +  I       SL+I      D GEY+ KA N  G  +   ++TVT
Sbjct: 157  AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 211



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 66/306 (21%), Positives = 123/306 (40%), Gaps = 9/306 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  +N       +A F+  + G+P   ++W +    L E +   + + +     +
Sbjct: 1712 PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVA--T 1769

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I+ +  G  G YTC A+N+ G   C  ++  +                    T+E   
Sbjct: 1770 LQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVV 1829

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             GT     +  +  +++  +     S    F+ +   +R+ + V  ++S    +  E+D 
Sbjct: 1830 AGTPELKVKWLKDGKQIVPSRYFSMS----FENNVASFRI-QSVMKQDSGQYTFKVENDF 1884

Query: 251  QIST--EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
              S+     R L    PP   +K        G+    + ++SG+      WFK+G+ +  
Sbjct: 1885 GSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 1944

Query: 309  SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
            S K+ ++      +L V N +  D+ +YT    N  G    SG L V+ P    V+  R 
Sbjct: 1945 SAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQ 2004

Query: 369  QYITDT 374
            Q I D+
Sbjct: 2005 QAIPDS 2010



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 54/192 (28%), Positives = 85/192 (44%), Gaps = 12/192 (6%)

Query: 3044 TGRPPEFTTVF--KDI-VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
            T R P+ +  F  K + +D+  G+ A +E  +  TG Q M I W  + K I         
Sbjct: 2928 TAREPKKSPFFDIKPVSIDVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTIT 2985

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL     DSG Y+C+ATN  G+   S +L     S  + P+F   ++  + 
Sbjct: 2986 CVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL-----SVKEPPKFVKKLEASKV 3040

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
             K G+S   EC +     P++K+ W+ N   +  S +          +L I      DSG
Sbjct: 3041 AKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSG 3098

Query: 3221 EYVCRAYNKYGE 3232
            +Y+C A+N  G+
Sbjct: 3099 DYICEAHNGVGD 3110



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 65/231 (28%), Positives = 97/231 (41%), Gaps = 31/231 (13%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP   T   D + SE   A F+CR   V+ + ++V W+   K +   SR   +  F    
Sbjct: 9    PPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP-SRFFRMTQFEDTY 64

Query: 3617 -LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             LEI   Y  D G YT  A N  G+ + +  L                       S++  
Sbjct: 65   QLEIAEAYPEDEGTYTFVANNAVGQVSSTANL-----------------------SLEAP 101

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E  LH+R E  IE E    P    +I+  ++V  G    F C ++    P +R  WF  G
Sbjct: 102  ESILHERIEQEIEMEMKAAPVIKRKIEP-LEVALGHLAKFTCEIQSA--PNVRFQWFKAG 158

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            R      +    +     +L+I      D GEYTC+A+N++GS + TA +T
Sbjct: 159  REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT 209



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 6/182 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P FVK   D     G+       V G     VTW      IR+D   K+  + +G   L+
Sbjct: 589 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGVAVLI 647

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I +V +S  G  TC+A N++G       L  I KE     K +ER   + V  G+P  L 
Sbjct: 648 IPDVQISFGGKYTCLAENEAGSQTSVGEL--IVKEPA---KIIERAELIQVTAGDPATLE 702

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               GTP  +  W KDG P++ + + RI      + L    A+  D+  Y     N  GS
Sbjct: 703 YTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGS 762

Query: 572 TA 573
           ++
Sbjct: 763 SS 764



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 6/200 (3%)

Query: 380 EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
           E    + ++ +AP F K  ++ D       R DC++ G     V+WF + ++I     ++
Sbjct: 766 ETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYR 825

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           I   E G  +L I  V ++D+G  TC A N  G       L V E      P FV +  +
Sbjct: 826 IAFVE-GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEP-----PSFVTKPGS 879

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
            +V  G  V L +   G+    I W K    ++      I  +   S+L++   K SD+ 
Sbjct: 880 KDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSG 939

Query: 560 WYQCTAQNVAGSTATRARLY 579
            Y C   NVAG     A L+
Sbjct: 940 TYTCKVSNVAGGVECSANLF 959



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 64/255 (25%), Positives = 105/255 (41%), Gaps = 19/255 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP+F      ++ +  GQ   +E  +  TG   + + W+ +G  I A  +    +  G+ 
Sbjct: 1525 PPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFIDGLA 1582

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
              +I G +  +SGTY C A N  G A  S++L    K K + P F   ++ +E +K    
Sbjct: 1583 TFQISGARVENSGTYVCEARNDAGTASCSIEL----KVK-EPPTFIRELKPVEVVK-YSD 1636

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               EC V     P  ++ W  N + +R S +           L I      D+GEY C  
Sbjct: 1637 VELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIV 1694

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
             N+ G        +C     V L+   P  + KI    ++  +     ST +  PP  IT
Sbjct: 1695 SNEGG--------SCSCSTRVALKE-PPSFIKKIENTTTVLKSSATFQSTVAGSPPISIT 1745

Query: 3287 QIQDVTKLVEGQSAH 3301
             ++D   L E  + +
Sbjct: 1746 WLKDDQILDEDDNVY 1760



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 66/231 (28%), Positives = 98/231 (42%), Gaps = 24/231 (10%)

Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631
            E+    P   T L++    EGQ A F+ R   VS   LKV WY  +K +K    F  T  
Sbjct: 4    EMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQF 60

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691
                 L+I    PED GTYT  A NA+G+  ++    + + +SI     HE    R+ Q 
Sbjct: 61   EDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESIL----HE----RIEQE 112

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751
             +             +  APV    ++ + VA    A F   +     P +R +W + G 
Sbjct: 113  IEME-----------MKAAPVIKRKIEPLEVALGHLAKFTCEI--QSAPNVRFQWFKAGR 159

Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             I  S++ +        +L +      D G YTC+A NE G    ++TL V
Sbjct: 160  EIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 8/194 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F+   +D+ + + G    ++ ++  +G + + + W+ +GK ++ S  ++T +     
Sbjct: 4721 PPSFSRQLRDVQE-TVGLPVVFDCAI--SGSEPISVSWYKDGKPLKDSPNVQTSFLDNTA 4777

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L I  T  + +G YSC ATN  G A  S +L   +      P F   +  ++ +  G+S
Sbjct: 4778 TLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGK--NPPFFDIRLAPVDAVV-GES 4834

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A FEC V       +K+ W  + + +R   + +         L +      DSG+Y C A
Sbjct: 4835 ADFECHVTGTQ--PIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYA 4892

Query: 3227 YNKYGEDFTRATIN 3240
             N+ G+D   A +N
Sbjct: 4893 VNEVGKDSCTAQLN 4906



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 111/504 (22%), Positives = 202/504 (40%), Gaps = 49/504 (9%)

Query: 71  PPIF-EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           PP F +++  +     G +A+   KL+G+P   V+W +    L E N   M +     + 
Sbjct: 401 PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYF--VNSEA 458

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
            L I  +   D G Y+C A N  G   CS  I  +               R  +  ++ +
Sbjct: 459 ILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCE 518

Query: 190 AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFK-VDTFEYRLLREVSFRESITKRYVGES 248
             GT  +     +  +++  +      S      ++ F +    +V   E +    VG+ 
Sbjct: 519 VSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSA-DVGEYECVVANEVGKC 577

Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
              ++T + +      PP   +K  +     G     Q  + G+    VTW K  + +  
Sbjct: 578 GC-MATHLLKE-----PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIRE 631

Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
             K ++  ++    L + + Q S  G YT LAEN  G   + G L V+ P +     +R+
Sbjct: 632 DGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKII---ERA 688

Query: 369 QYITDTQ-QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
           + I  T     T E        L P++ K        +G+       V  + Y  +++  
Sbjct: 689 ELIQVTAGDPATLEYTVAGTPELKPKWYK--------DGRPL-----VASKKY-RISFKN 734

Query: 428 NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
           N  Q++  Y+ ++  ++SG +   I+N    + G  +C       ET F     V++++ 
Sbjct: 735 NVAQLK-FYSAEL--HDSGQYTFEISN----EVGSSSC-------ETTF----TVLDRD- 775

Query: 488 VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
            +AP F +    ++        L+ +  G+   R++W KDG  I  +   RI    G ++
Sbjct: 776 -IAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 548 LDIPRAKASDAAWYQCTAQNVAGS 571
           L+I R   +DA  + C A N  GS
Sbjct: 835 LEIIRVDMNDAGNFTCRATNSVGS 858



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 51/178 (28%), Positives = 82/178 (46%), Gaps = 7/178 (3%)

Query: 402  DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
            DV  G+   F+C VTG     +TW  ++++IR   N+ I    +  H L I  V   DSG
Sbjct: 2946 DVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPH-LRILKVGKGDSG 3004

Query: 462  VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV-REGEPVVLNARAVGTPTP 520
              TC A N  G+     +L+V E      PKFV++     V ++GE + L  +  G+P  
Sbjct: 3005 QYTCQATNDVGKDMCSAQLSVKEP-----PKFVKKLEASKVAKQGESIQLECKISGSPEI 3059

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +++W ++   +  + +  +      + L I  A A D+  Y C A N  G  +    L
Sbjct: 3060 KVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTAL 3117



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 52/187 (27%), Positives = 83/187 (44%), Gaps = 6/187 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F+K  ++          F   V G P   +TW  +D+ + +D N  I   +S    L 
Sbjct: 1713 PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVA-TLQ 1771

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            I +V    SG  TC A+N+SG       L V E  Q+V     E+  +++V E +P+ L 
Sbjct: 1772 IRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIV-----EKAKSVDVTEKDPMTLE 1826

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
                GTP  ++ W KDG  I+P+    +  +   ++  I      D+  Y    +N  GS
Sbjct: 1827 CVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGS 1886

Query: 572  TATRARL 578
            ++  A L
Sbjct: 1887 SSCDAYL 1893



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 62/286 (21%), Positives = 112/286 (39%), Gaps = 10/286 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  K     +  + + E ++ G P   V+W +    +    KY++   ++    +
Sbjct: 1619 PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL--TDRVSVFN 1676

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I +  P D GEY C   N+ G   CS  +  +                  S T +   
Sbjct: 1677 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTV 1736

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G+   +    +  Q +   +    S  D   V T + R     S     + RY  ++  
Sbjct: 1737 AGSPPISITWLKDDQILDEDDNVYISFVD--SVATLQIR-----SVDNGHSGRYTCQAKN 1789

Query: 251  QISTEIDRSLGPV-SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
            +   E   +   V  P +I +K ++  + E      +  ++G P  +V W K+G++++ S
Sbjct: 1790 ESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPS 1849

Query: 310  NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
                +   +N  + R+++  K DSG YT   EN  G      YL V
Sbjct: 1850 RYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV 1895



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 55/195 (28%), Positives = 85/195 (43%), Gaps = 5/195 (2%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            I  + L P F +  +D   T G    F+CR+ G    +V+W+ +   ++DD N  +  + 
Sbjct: 3774 IKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDAN--LQTSF 3831

Query: 445  SGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
              N A L I     S  G   C A N  G  +   +L + E E  V P F  +  ++++ 
Sbjct: 3832 VHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE--VPPFFDLKPVSVDLA 3889

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             GE         GT   +ITW KD   I P    ++      +TL + +    DA  Y C
Sbjct: 3890 LGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTC 3949

Query: 564  TAQNVAGSTATRARL 578
             A N+AG  +  A+L
Sbjct: 3950 YASNIAGKDSCSAQL 3964



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 82/337 (24%), Positives = 143/337 (42%), Gaps = 46/337 (13%)

Query: 242  KRYVGESDVQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF 300
            K  VG+S+  +S  + DR    + PP   +K ++     GA    + ++SG+    V WF
Sbjct: 3385 KNSVGKSNCTVSVHVSDR----IVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWF 3440

Query: 301  KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
            ++G  +++  K +   + N  TL +   + SD+G YT +A N  G    S  L V+ P  
Sbjct: 3441 QDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEP-P 3499

Query: 361  SYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ-DRDVTEGKMTRFDCRVTGRP 419
            S+ Q   S  +           I    +   P  VK  +  R++  G+     C ++   
Sbjct: 3500 SFEQTPDSVEVLPGMSLTFTSVI----RGTPPFKVKWFKGSRELVPGE----SCNIS--- 3548

Query: 420  YPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCR 479
               +  F+ + ++      ++   ESG+++ ++TN    D+G  +C              
Sbjct: 3549 ---LEDFVTELEL-----FEVQPLESGDYSCLVTN----DAGSASCTT------------ 3584

Query: 480  LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539
             ++  KE      FV+R +  +V  G P+VL A   GTP   ++W KD   I  +    I
Sbjct: 3585 -HLFVKEPAT---FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSI 3640

Query: 540  HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
                 ++ L+I  +   D A Y C  +N AG     A
Sbjct: 3641 TMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEA 3677



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 90/395 (22%), Positives = 159/395 (40%), Gaps = 30/395 (7%)

Query: 1170 EEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            E + K  P F++ L  P  +  G N  L+C  E  G     + WF + + +    +++ +
Sbjct: 489  EIVIKEPPSFIKTLE-PADIVRGTNALLQC--EVSGTGPFEISWFKDKKQIRSSKKYRLF 545

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE-QI 1288
                 V L+I    SAD GEY     N +G     A   + E    V    +  A+  Q 
Sbjct: 546  SQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQT 605

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHL----ECRLQPVGDQTMRV 1344
              L+ A R ++ +   +T M+  +  R    I+      V +    + ++   G  T   
Sbjct: 606  VTLQAAVRGSEPI--SVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLA 663

Query: 1345 EWFCNGKPIKTGHRF--RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEA-------- 1394
            E    G     G      PA   +   L  ++     +  YT   T +L           
Sbjct: 664  ENEA-GSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPL 722

Query: 1395 VTSCALRVIAKKDLILESQHPSGL-EKIQYLEDTSRYKKTDIIDESVTIKPR----FVTR 1449
            V S   R+  K ++     + + L +  QY  + S    +   + + T+  R    F T+
Sbjct: 723  VASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTK 782

Query: 1450 P-KSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            P +++++V+ G     +CK+       ++V WFK+G+ +    R+R     G  +L+II 
Sbjct: 783  PLRNVDSVVNGT-CRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIR 839

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            +   D+G +TCRA N VG+ + S  L  +     V
Sbjct: 840  VDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFV 874



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 49/196 (25%), Positives = 82/196 (41%), Gaps = 6/196 (3%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + + ++ + P F K     D   G     +C+V+G       WF + ++I     ++++ 
Sbjct: 1893 LRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVC 1952

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +E  + +L + N+ L D+   TC   N +G+ A    L V E      P F+ +      
Sbjct: 1953 HER-SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEP-----PSFLVKPGRQQA 2006

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
                 V   A   GTP  +I W KD V ++  P+  I  +G  S L++    AS    Y 
Sbjct: 2007 IPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYT 2066

Query: 563  CTAQNVAGSTATRARL 578
            C   N  GS +    L
Sbjct: 2067 CHVTNDVGSDSCTTML 2082



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 51/188 (27%), Positives = 78/188 (41%), Gaps = 7/188 (3%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            IE+  K   P F++  +  +V +      +C VTG P  EVTW  N+R+IR    +  L 
Sbjct: 1612 IELKVKE-PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYT-LT 1669

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +      L IT    SD+G   C+  N+ G  +  C   V  KE    P F+++      
Sbjct: 1670 DRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCS--CSTRVALKE---PPSFIKKIENTTT 1724

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
                     +   G+P   ITW KD   +  +  + I      +TL I       +  Y 
Sbjct: 1725 VLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYT 1784

Query: 563  CTAQNVAG 570
            C A+N +G
Sbjct: 1785 CQAKNESG 1792



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 49/193 (25%), Positives = 83/193 (43%), Gaps = 10/193 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP+F    +    +  G  +  E  +   G   + + WF N   + AS + R  +   + 
Sbjct: 2087 PPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 2144

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            V+++    T DSG + C A N  G    S K+  + K   + P F++    +E LK+ + 
Sbjct: 2145 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV--IVK---EPPVFSSFPPIVETLKNAE- 2198

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               EC +     P  ++ WY + + +R S + K  S      + I      D GEY C+A
Sbjct: 2199 VSLECEL--SGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKA 2256

Query: 3227 YNKYGEDFTRATI 3239
             N+ G D    T+
Sbjct: 2257 QNEVGSDTCVCTV 2269



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 68/238 (28%), Positives = 109/238 (45%), Gaps = 30/238 (12%)

Query: 627 PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686
           P +E  VYPP   I PL+     EG    F+ R   V    +K+ W    + I+ S RF 
Sbjct: 1   PDQEMPVYPPA-IITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPS-RFF 55

Query: 687 SIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745
            + +F     L++     +D G YT  A +A G   + A L +          + PE++ 
Sbjct: 56  RMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSL----------EAPESIL 105

Query: 746 YIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVE 805
           + +++E        + IE +    P   R ++ L E+  G  A F  ++   S P +R +
Sbjct: 106 H-ERIE--------QEIEMEMKAAPVIKRKIEPL-EVALGHLAKFTCEIQ--SAPNVRFQ 153

Query: 806 WYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           W+K GR I  S +  SI +  Y+ SL I+  +  D G YT +A N+ G    TA++ V
Sbjct: 154 WFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 62/225 (27%), Positives = 106/225 (47%), Gaps = 28/225 (12%)

Query: 2235 EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT 2294
            +E  + PP  +T L+ T    EG+ A F+C+V      +L++ +Y   K ++ +  F +T
Sbjct: 3    QEMPVYPPAIITPLQDTV-TSEGQPARFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMT 58

Query: 2295 -FDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKI 2353
             F+  Y  L+I    PED G Y+  A NA+G  +S  ++++ A  SI+ E    E +E  
Sbjct: 59   QFEDTY-QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQE-IE-- 114

Query: 2354 RELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWF 2413
             E+++A   KR               +PL+    +  G  A F C +     P ++ +WF
Sbjct: 115  MEMKAAPVIKRK-------------IEPLE----VALGHLAKFTCEI--QSAPNVRFQWF 155

Query: 2414 RNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            +  + I +S + +        S+ I   +  D G Y C+ASN  G
Sbjct: 156  KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYG 200



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 46/197 (23%), Positives = 86/197 (43%), Gaps = 6/197 (3%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            +++S++A+ P F +  ++     G     +C+V G     V WF    +I     ++   
Sbjct: 2456 VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF 2515

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +++    L + ++  SD G  TCVA N +G    +CR  +  +E    P FV+    L V
Sbjct: 2516 SDNVC-TLQLNSLDSSDMGNYTCVAANVAGSD--ECRAVLTVQEP---PSFVKEPEPLEV 2569

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              G+ V   +   GTP  ++ W +    ++      I+ +   + L++     S +  Y 
Sbjct: 2570 LPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 2629

Query: 563  CTAQNVAGSTATRARLY 579
            C   N AG  +   RL+
Sbjct: 2630 CVVSNNAGQASCTTRLF 2646



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 102/509 (20%), Positives = 189/509 (37%), Gaps = 52/509 (10%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P+ ++  +    A G  AKF  +++  P     W +    + E +K S+R ++    + +
Sbjct: 121 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 180

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
           L  Q+   D GEYTC A N+YG   C+  +                    V +  +    
Sbjct: 181 LRTQVV--DCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFIC- 237

Query: 192 GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR--YVGESD 249
                T   +   + +   +G   S + ++++   E + + E+S   +I  R  Y  ++ 
Sbjct: 238 -----TVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELS-NLTIQDRGVYSCKAS 291

Query: 250 VQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
            +   +I    L  +  P   ++    +         + Q+  + +  VTW K+GQ+L  
Sbjct: 292 NKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPP 351

Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
              ++I       TL +   +  DSG Y   A N  G    S  + V  P  S+V+    
Sbjct: 352 GKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREP-PSFVKKVDP 410

Query: 369 QYITDTQQRETEERIEISEK-ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            Y+    +     R+    K +   Q      +++++E    R              +F+
Sbjct: 411 SYLMLPGE---SARLHCKLKGSPVIQVTWFKNNKELSESNTVRM-------------YFV 454

Query: 428 NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
           N   I D  + K  V +SG+++    N   SDS                 C   ++ KE 
Sbjct: 455 NSEAILDITDVK--VEDSGSYSCEAVNDVGSDS-----------------CSTEIVIKE- 494

Query: 488 VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
              P F++     ++  G   +L     GT    I+W KD   I  + + R+ +      
Sbjct: 495 --PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVC 552

Query: 548 LDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           L+I    ++D   Y+C   N  G     A
Sbjct: 553 LEIFSFNSADVGEYECVVANEVGKCGCMA 581



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 60/221 (27%), Positives = 97/221 (43%), Gaps = 11/221 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    KDI + + G        L   G   + + W+ +G  +     ++T +   + 
Sbjct: 2839 PPSFARQLKDI-EQTVGLPVTLTCRL--NGSAPIQVCWYRDGVLLRDHENLQTSFVDNVA 2895

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L+IL T  + SG YSC A+N  G A  S +L   +  K   P F     +I+ +  G+S
Sbjct: 2896 TLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKK--SPFFDIKPVSIDVIA-GES 2952

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A FEC V       M+I W  + + +R               L I      DSG+Y C+A
Sbjct: 2953 ADFECHVTGAQ--PMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQA 3010

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQ 3267
             N  G+D   A ++   +   +++ L+   +AK  + ES+Q
Sbjct: 3011 TNDVGKDMCSAQLS-VKEPPKFVKKLEASKVAK--QGESIQ 3048



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 54/223 (24%), Positives = 92/223 (41%), Gaps = 16/223 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G   + +EW+ +GK + +S + +  +   +  L IL  +  D+GTY+ +  N  G++  +
Sbjct: 2394 GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCT 2453

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++  D++    P FT  ++N  G+  G S   EC V       + + W+H    +   
Sbjct: 2454 AVVDVSDRA--VPPSFTRRLKNTGGVL-GASCILECKV--AGSSPISVAWFHEKTKIVSG 2508

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD 3255
             + +T        L +    + D G Y C A N  G D  RA +             +P 
Sbjct: 2509 AKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQ----------EPP 2558

Query: 3256 SLAKIRE-LESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEG 3297
            S  K  E LE L G      S     PP  +   +   +LV+G
Sbjct: 2559 SFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG 2601



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 65/271 (23%), Positives = 115/271 (42%), Gaps = 36/271 (13%)

Query: 912  KTPIKDQ----ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            K P+ DQ    +++ EG +      ++  G   +R++WLK GR ++ S R +  F  G  
Sbjct: 5009 KPPVFDQHLTPVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFASGTA 5066

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             L ++ V   D+G Y C+A N  G  TT + +TI  K  +   ++               
Sbjct: 5067 VLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATK--------------- 5111

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGK--Q 1085
                  +  +    +P+ +       ++VE  +A F A+V    D    V+W   GK  Q
Sbjct: 5112 --KAAVDGRLFFVSEPQSI-------RVVEKTTATFIAKV--GGDPIPNVKW-TKGKWRQ 5159

Query: 1086 ITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID-TS 1144
            +    R+  +       L+I      DSG+Y  VA N  GE + + ++ V+ R   +   
Sbjct: 5160 LNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIE 5219

Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKS 1175
               R + +KT  +++    E    I E+ K+
Sbjct: 5220 GDLRAMLKKTPILKKGAGEEEEIDIMELLKN 5250



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 72/298 (24%), Positives = 124/298 (41%), Gaps = 16/298 (5%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIG 137
            ++ R  +   A F  K+ G+P P V WT+ K    + N+    +  Q GD + L I+   
Sbjct: 5126 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR--QLNQGGRVFIHQKGDEAKLEIRDTT 5183

Query: 138  PGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYT 197
              D G Y C A N++GE   +V +Q +                  +  ++  A   +   
Sbjct: 5184 KTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEID 5243

Query: 198  T-EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLR----EVSFRESITKRYVGESDVQI 252
              E  +      Y          DF+     + LL+    E + R  I +    E D + 
Sbjct: 5244 IMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKE 5303

Query: 253  STE----IDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGN-PRPRVTWFKNGQRLI 307
              E    I + L    P  + +   N  + +  DA F++ +  N P  +++W+K  ++L 
Sbjct: 5304 FEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLE 5363

Query: 308  NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
             S+K EI    +  TLRV+N Q  D G+Y L+   P+  I ++    +E   E ++QD
Sbjct: 5364 PSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC-GPH--IASAKLTVIEPAWERHLQD 5418



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 52/192 (27%), Positives = 82/192 (42%), Gaps = 10/192 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F         +  G+ A     L   G   + + WF N K +  S+ +R  +     
Sbjct: 401  PPSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVNSEA 458

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I   K  DSG+YSC A N  G    S   E V K   + P F   ++  + ++ G +
Sbjct: 459  ILDITDVKVEDSGSYSCEAVNDVGSDSCST--EIVIK---EPPSFIKTLEPADIVR-GTN 512

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A  +C V        +I W+ + + +R S + +  S    V L+I    + D GEY C  
Sbjct: 513  ALLQCEVSGTG--PFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 570

Query: 3227 YNKYGEDFTRAT 3238
             N+ G+    AT
Sbjct: 571  ANEVGKCGCMAT 582



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 46/197 (23%), Positives = 86/197 (43%), Gaps = 6/197 (3%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + +S++ + P F++  +D +   G     +CRV+G     V WF +  +I      +   
Sbjct: 3397 VHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSF 3456

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +E+    L ++ +  SD+G+ TCVA N +G       L V E      P F +   ++ V
Sbjct: 3457 SENVC-TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEP-----PSFEQTPDSVEV 3510

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              G  +   +   GTP  ++ W K    ++P     I  +   + L++   +  ++  Y 
Sbjct: 3511 LPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYS 3570

Query: 563  CTAQNVAGSTATRARLY 579
            C   N AGS +    L+
Sbjct: 3571 CLVTNDAGSASCTTHLF 3587



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 99/506 (19%), Positives = 194/506 (38%), Gaps = 55/506 (10%)

Query: 71   PPIFEQIFKNARFAQGGNA-KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            P  F +  + ++  + G+A +   K+ G P   ++W      + E +K+ M + E T   
Sbjct: 963  PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTA-- 1020

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
             L +  +G  D GEY C A+N+ G   CS  +  +               +     +  +
Sbjct: 1021 VLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAE 1080

Query: 190  AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESD 249
              GT  +        +   + + T   S   +K  TF    L  +   + +     GE  
Sbjct: 1081 VAGTPPF--------EITWFKDNTILRSGRKYK--TFIQDHLVSLQILKFVAAD-AGEYQ 1129

Query: 250  VQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
             +++ E+  S+         PP   +K  ++    G  A FQ  L G+    VTW K+  
Sbjct: 1130 CRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSD 1189

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
             +   +   +   +N  +L +   +    G Y   A+N  G    S  L+V+ P  +  +
Sbjct: 1190 EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPA-TITE 1248

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            +  S  +T       + +   +++  A  F      +++T G  +++   VT      + 
Sbjct: 1249 EAVSIDVTQGDPATLQVKFSGTKEITAKWFK---DGQELTLG--SKYKISVTDT--VSIL 1301

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
              I+  +            +SG +   + N    D G  +C AR           +NV+ 
Sbjct: 1302 KIISTEK-----------KDSGEYTFEVQN----DVGRSSCKAR-----------INVL- 1334

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
             + ++ P F ++   ++  +G  + L     G+    I W KD   I  + + +      
Sbjct: 1335 -DLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDN 1393

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
             + L+I + + +D+  Y C+A N AG
Sbjct: 1394 TAFLEISQLEGTDSGTYTCSATNKAG 1419



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 42/176 (23%), Positives = 83/176 (47%), Gaps = 7/176 (3%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            +D+++G  A  +     +G + +  +WF +G+ +    + +      + +L+I+ T+  D
Sbjct: 1253 IDVTQGDPATLQVKF--SGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKD 1310

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            SG Y+    N  G++    ++  +D      P FT  ++ ++ +K G     EC +V   
Sbjct: 1311 SGEYTFEVQNDVGRSSCKARINVLDLI--IPPSFTKKLKKMDSIK-GSFIDLEC-IVAGS 1366

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P + I+W+ + Q +  S + K         L+I+  +  DSG Y C A NK G +
Sbjct: 1367 HP-ISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHN 1421



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 67/289 (23%), Positives = 112/289 (38%), Gaps = 9/289 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  K     +G     E  + G+    + W +    +    KY   +++ T    
Sbjct: 1339 PPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTA--F 1396

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I Q+   D G YTC+A N+ G   CS ++  +                +    ++   
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALV 1456

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             GT   T +  +  +++   +G   S   D   DT     L      +S T      +DV
Sbjct: 1457 GGTAPMTIKWFKDNKELH--SGAARSVWKD---DTSTSLELFAAKATDSGTYICQLSNDV 1511

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
              +T    +L    PP+  +KP     L+ G    F+ Q++G P+ RV+W+ +G  +   
Sbjct: 1512 GTATS-KATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAI 1570

Query: 310  NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             KH I       T ++   +  +SG Y   A N  G    S  L V+ P
Sbjct: 1571 QKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEP 1619



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 51/193 (26%), Positives = 83/193 (43%), Gaps = 11/193 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F +  K +     G+ A +  ++  TG   +   W  +G  +  S   R   A    
Sbjct: 215  PPTFLSRPKSLTTFV-GKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWRISDAENKH 271

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +LE+      D G YSC+A+NK+G      +L  +D     KP F   ++ ++   + + 
Sbjct: 272  ILELSNLTIQDRGVYSCKASNKFGADICQAELIIID-----KPHFIKELEPVQSAIN-KK 325

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             H EC V   +D  + + W  +GQ +      K   +     L+I   +  DSG YVC A
Sbjct: 326  VHLECQV--DEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTA 383

Query: 3227 YNKYGEDFTRATI 3239
             N+ G     AT+
Sbjct: 384  SNEAGSSSCSATV 396



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 3/125 (2%)

Query: 3826 VSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP F+ ++  S+ +   E  R  C++  K  P +++ W++N K L   +  R  +  
Sbjct: 398  VREPPSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVN 455

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
                LDI  V  EDSG Y C AVND G D     I  K+ P  I   +    ++ + AL 
Sbjct: 456  SEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALL 515

Query: 3945 QMEAT 3949
            Q E +
Sbjct: 516  QCEVS 520



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 58/222 (26%), Positives = 85/222 (38%), Gaps = 17/222 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG   + I WF N + I+ S + R  +     VL +      DSG Y C A N+ G    
Sbjct: 989  TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHC 1048

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            S  +  V +S    P FT   + IE LK+               P  +I W+ +   +R 
Sbjct: 1049 S-SIVIVKES----PYFTKEFKPIEVLKE---YDVMLLAEVAGTPPFEITWFKDNTILRS 1100

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254
              + KT      V L I      D+GEY CR  N+ G     A +              P
Sbjct: 1101 GRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTL---------REPP 1151

Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
              + KI    SL+G      +T     P  +T ++D  ++ E
Sbjct: 1152 SFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITE 1193



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 52/213 (24%), Positives = 91/213 (42%), Gaps = 9/213 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    KD+ +     +A +E  +   G + + + W+ +G  ++    ++T +   + 
Sbjct: 3780 PPFFARKLKDVHETLGFPVA-FECRI--NGSEPLQVSWYKDGVLLKDDANLQTSFVHNVA 3836

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L+IL T  +  G Y+C A+N  G A  S KL     S+ + P F         L  G+S
Sbjct: 3837 TLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL---SEHEVPPFFDLKPVSVDLALGES 3893

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              F+C V       +KI W  + + +R     K         L +      D+G+Y C A
Sbjct: 3894 GTFKCHV--TGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYA 3951

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAK 3259
             N  G+D   A +    +   +++ L+P  + K
Sbjct: 3952 SNIAGKDSCSAQLGVQ-EPPRFIKKLEPSRIVK 3983



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 47/196 (23%), Positives = 83/196 (42%), Gaps = 3/196 (1%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + + E+ L P F +  +D   T G    FDC ++G     V+W+ + + ++D  N +   
Sbjct: 4713 LTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSF 4772

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
             ++    L I     S +G  +C A N  G  +   RL + E +    P F  R + ++ 
Sbjct: 4773 LDN-TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN--PPFFDIRLAPVDA 4829

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              GE         GT   +++W KD   I    + +I     ++ L + +    D+  Y 
Sbjct: 4830 VVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYT 4889

Query: 563  CTAQNVAGSTATRARL 578
            C A N  G  +  A+L
Sbjct: 4890 CYAVNEVGKDSCTAQL 4905



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 51/246 (20%), Positives = 102/246 (41%), Gaps = 16/246 (6%)

Query: 3056 DIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT 3115
            +++ ++ G  A  E ++   G   +  +W+ +G+ + AS + R  +   +  L+    + 
Sbjct: 689  ELIQVTAGDPATLEYTV--AGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAEL 746

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
             DSG Y+   +N+ G +        +D+     P FT  ++N++ + +G +   +C +  
Sbjct: 747  HDSGQYTFEISNEVGSSSCETTFTVLDRDIA--PFFTKPLRNVDSVVNG-TCRLDCKI-- 801

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
                 M++ W+ +G+ +  S R +     G   L+I     +D+G + CRA N  G    
Sbjct: 802  AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSK-- 859

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLV 3295
                      G  +    P  + K    + L G+     ST     P  I   +   +LV
Sbjct: 860  -------DSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELV 912

Query: 3296 EGQSAH 3301
             G S +
Sbjct: 913  SGGSCY 918



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 63/230 (27%), Positives = 98/230 (42%), Gaps = 29/230 (12%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P     L +  T EG     +CR   V    ++V W+   K IK    FR     D   L
Sbjct: 10   PAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQL 66

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRY 1430
            ++   YPED G YT  A N +G+  ++  L + A + ++    H    E+I+  E     
Sbjct: 67   EIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESIL----H----ERIEQ-EIEMEM 117

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
            K   +I     I+P           V  G    F C+++  +  N++ +WFK G+ +   
Sbjct: 118  KAAPVIKRK--IEPL---------EVALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYES 164

Query: 1491 HRFRPIHDFGYV-ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
             +   I    Y+ +L+I+     D G YTC+A N  G+  VSC  T   T
Sbjct: 165  DKC-SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS--VSCTATLTVT 211



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/194 (26%), Positives = 87/194 (44%), Gaps = 13/194 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP FT   K + D  +G     E   I  G   + I+WF + + I AS + +  +     
Sbjct: 1339 PPSFTKKLKKM-DSIKGSFIDLEC--IVAGSHPISIQWFKDDQEISASEKYKFSFHDNTA 1395

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LEI   + TDSGTY+C ATNK G  + S  L     +  + P F   ++  +      +
Sbjct: 1396 FLEISQLEGTDSGTYTCSATNKAGHNQCSGHL-----TVKEPPYF---VEKPQSQDVNPN 1447

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV-SDFGFVVLDIAYTQNHDSGEYVCR 3225
               +   +      M I+W+ + + + HS   ++V  D     L++   +  DSG Y+C+
Sbjct: 1448 TRVQLKALVGGTAPMTIKWFKDNKEL-HSGAARSVWKDDTSTSLELFAAKATDSGTYICQ 1506

Query: 3226 AYNKYGEDFTRATI 3239
              N  G   ++AT+
Sbjct: 1507 LSNDVGTATSKATL 1520



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 50/190 (26%), Positives = 81/190 (42%), Gaps = 10/190 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAEI 3134
            G   M I+WF + K +  S   R+V+       LE+   K TDSGTY C+ +N  G A  
Sbjct: 1458 GTAPMTIKWFKDNKELH-SGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATS 1516

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L   +      P+F      +  L++GQS  FEC +     P +++ WY +G  +  
Sbjct: 1517 KATLFVKEP-----PQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITA 1569

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254
              +       G     I+  +  +SG YVC A N  G       +    +   ++  L+P
Sbjct: 1570 IQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELK-VKEPPTFIRELKP 1628

Query: 3255 DSLAKIRELE 3264
              + K  ++E
Sbjct: 1629 VEVVKYSDVE 1638



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 50/180 (27%), Positives = 75/180 (41%), Gaps = 7/180 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F +        +G      C ++G P  EV W  + +Q+R+    KI       + L 
Sbjct: 3123 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTN-LH 3181

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            I N+  SD G   C A N+ G     C +   E      P+FV++ S  +   G+ V L 
Sbjct: 3182 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEP-----PRFVKKLSDTSTLIGDAVELR 3236

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   G     + W KD   +I   E  RI      +TL +   +AS++  Y C  +N AG
Sbjct: 3237 AIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAG 3296



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 55/228 (24%), Positives = 94/228 (41%), Gaps = 28/228 (12%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GF 3752
            PP     ++D +   EG P  F CRV       +++ W+   +     SR   +  F   
Sbjct: 9    PPAIITPLQDTV-TSEGQPARFQCRVSGTD---LKVSWYSKDKKIKP-SRFFRMTQFEDT 63

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
              L+I   Y  D G YT  A N  G  ++TA ++  A          P+ +  E+I++  
Sbjct: 64   YQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEA----------PESILHERIEQ-- 111

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
               I    K  P++        +I+   V      +F C ++    P +R +W++ G+ +
Sbjct: 112  --EIEMEMKAAPVIKR------KIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAGREI 161

Query: 3873 PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
                +          SL+IL     D GEY C+A N++G     AT++
Sbjct: 162  YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT 209



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 29/230 (12%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P    PL +     EG+ A F+ R++ TD   LKV WY   K +K    FR         
Sbjct: 10   PAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFRMTQFEDTYQ 65

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            LEI+  YPED G Y   A N  G+  +TA++ ++   +I+ E      +E  I       
Sbjct: 66   LEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHER-----IEQEI------- 113

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
                       E E    P        L ++    A F C +   +  ++R +WF  G+ 
Sbjct: 114  -----------EMEMKAAPVIKRKIEPLEVALGHLAKFTCEI--QSAPNVRFQWFKAGRE 160

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +    +    +      LEI      D G YTCKA+N +G  + +  L V
Sbjct: 161  IYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 9/292 (3%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E  PP F    K+     G  AKF   + G P     W +  A L     +  R ++   
Sbjct: 212 EAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNW--RISDAEN 269

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVE 187
              L +  +   D G Y+C A N++G  IC   +                   +    +E
Sbjct: 270 KHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLE 329

Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247
            +    +  T   S+  QK+    G D+    + K+ T E  L +    ++S T      
Sbjct: 330 CQVDEDRKVTVTWSKDGQKLP--PGKDYKICFEDKIATLEIPLAK---LKDSGTYVCTAS 384

Query: 248 SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQ-EGADAQFQVQLSGNPRPRVTWFKNGQRL 306
           ++   S+    ++    PP   +K   S L   G  A+   +L G+P  +VTWFKN + L
Sbjct: 385 NEAG-SSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKEL 443

Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             SN   +   ++   L + + +  DSG Y+  A N  G    S  + ++ P
Sbjct: 444 SESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP 495



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 32/112 (28%), Positives = 60/112 (53%), Gaps = 2/112 (1%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            +D  + E I+   P FI +++      ++ V  EC+V+  ED K+ + W ++G+ LP G 
Sbjct: 296  ADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVD--EDRKVTVTWSKDGQKLPPGK 353

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
             Y+  ++    +L+I     +DSG Y+C A N+ G     AT++ ++ P  +
Sbjct: 354  DYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFV 405



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 65/289 (22%), Positives = 116/289 (40%), Gaps = 10/289 (3%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F +  +N      G  + + K+ G+    VSW +    +   ++Y + + E  G  SL
Sbjct: 778  PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE--GTASL 835

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
             I ++   D G +TC A N  G    S  +  +                  +  ++    
Sbjct: 836  EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQ 895

Query: 192  GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ 251
            G+   T    +  +++   +G     T +    + E  L++  S   + T +    S+V 
Sbjct: 896  GSTPLTIRWFKGNKELV--SGGSCYITKEALESSLELYLVK-TSDSGTYTCKV---SNVA 949

Query: 252  ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADA-QFQVQLSGNPRPRVTWFKNGQRLINSN 310
               E   +L    P    +K   S+L +  DA Q   +++G P  ++TWF N + +  S+
Sbjct: 950  GGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESS 1009

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESP 358
            KH +    +   LR+ +    DSG Y   A+N  G    S  + V ESP
Sbjct: 1010 KHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 1058



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 7/188 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P FV+  Q +DV      +    V G     + WF +++++       +  +++   +L 
Sbjct: 1433 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTST-SLE 1491

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVL 510
            +     +DSG   C   N  G    +  L V E      P+F+++ S  L +R G+    
Sbjct: 1492 LFAAKATDSGTYICQLSNDVGTATSKATLFVKEP-----PQFIKKPSPVLVLRNGQSTTF 1546

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              +  GTP  R++W  DG  I    +  I    G +T  I  A+  ++  Y C A+N AG
Sbjct: 1547 ECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAG 1606

Query: 571  STATRARL 578
            + +    L
Sbjct: 1607 TASCSIEL 1614



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 41/157 (26%), Positives = 65/157 (41%), Gaps = 8/157 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG   + + W  +G  I  S +   V      +LEIL +   D+G YSC   N+ G+   
Sbjct: 2675 TGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVC 2734

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               +  +     + P F T ++ +E    G S   +C V     P++ + WY     +R 
Sbjct: 2735 GALVSTL-----EPPYFVTELEPLEAAV-GDSVSLQCQV--AGTPEITVSWYKGDTKLRP 2786

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +   +T        L       +DSGEY C+A N  G
Sbjct: 2787 TPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIG 2823



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 84/394 (21%), Positives = 168/394 (42%), Gaps = 51/394 (12%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            ++V++ P F   L ++E V G    L+C++   G   +R+ W+     +++   ++  ++
Sbjct: 3679 VSVLEPPYFIEPLEHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFK 3736

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK----------KDLILESQH 1414
             +  +L +  V   D G Y+C+A N +G   +S  L + A+          KD+      
Sbjct: 3737 NNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGF 3796

Query: 1415 PSGLE-KIQYLE--DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQ-HV-HFECKLE 1469
            P   E +I   E    S YK   ++ +   ++  FV    +++ +   Q H+  + C   
Sbjct: 3797 PVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSA- 3855

Query: 1470 PVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
                SN       + + +   H   P  D   V+   +DL   +SG + C   ++ GT  
Sbjct: 3856 ----SNPLGTASSSAKLILSEHEVPPFFDLKPVS---VDLALGESGTFKC---HVTGTAP 3905

Query: 1530 VSCRLTCRSTTDIVRS--------TQNEAGLEQIQVLE-DRSKY--HRTDMVDEVTTQAP 1578
            +  ++T       +R          +N A L  ++V + D  +Y  + +++  + +  A 
Sbjct: 3906 I--KITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQ 3963

Query: 1579 ICTTS----LKNVE----IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +        +K +E    +K+ +   +E ++       +KV WY +   ++  S+F  + 
Sbjct: 3964 LGVQEPPRFIKKLEPSRIVKQDEFTRYECKI--GGSPEIKVLWYKDETEIQESSKFRMSF 4021

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                  L++ +   EDSG YTC A NA G A +S
Sbjct: 4022 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSS 4055



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 4/99 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V + P F +  H IET++G +VHLEC LQ  G     V W+ + + +++G +++   E
Sbjct: 4058 LKVKEPPIFRKKPHPIETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSE 4115

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGE--AVTSCALR 1401
                ++ +L+V   D G Y C+ATN +G    V S AL+
Sbjct: 4116 NFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 4154



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 44/148 (29%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            SGE + E +    SD      IV   P F  + K   V +   V     V     P   I
Sbjct: 1032 SGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGT--PPFEI 1089

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             W+++  +L SG +Y+T      VSL IL   A D+GEY CR  N+ G     A ++ ++
Sbjct: 1090 TWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLRE 1149

Query: 3924 LPDIILQNQVPRGMKRSEALTQMEATIK 3951
             P  I + +    ++   A  Q  AT+K
Sbjct: 1150 PPSFIKKIESTSSLRGGTAAFQ--ATLK 1175



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 37/112 (33%), Positives = 59/112 (52%), Gaps = 3/112 (2%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V + PRFI +L     + + +   YEC+I   P+  ++V WY +   +Q   ++R S
Sbjct: 3963 QLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPE--IKVLWYKDETEIQESSKFRMS 4020

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
                 A L++  +  EDSG+YTC+A N  G A SS  L V+ +  I R   H
Sbjct: 4021 FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK-EPPIFRKKPH 4071



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 44/187 (23%), Positives = 77/187 (41%), Gaps = 6/187 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F+K  +      G    F   + G     VTW  +  +I +D N ++   E+   +L 
Sbjct: 1151 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF-ENNVASLY 1209

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            ++ + +   G   C A+N +G       L+V E   +      E   +++V +G+P  L 
Sbjct: 1210 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIT-----EEAVSIDVTQGDPATLQ 1264

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             +  GT      W KDG  +    + +I      S L I   +  D+  Y    QN  G 
Sbjct: 1265 VKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGR 1324

Query: 572  TATRARL 578
            ++ +AR+
Sbjct: 1325 SSCKARI 1331



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 3/132 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875
            SD+     +V+ PPKF+ +++ S  V+  +  R EC++     P++R+ W+RN   LP+ 
Sbjct: 2075 SDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGS--PEIRVVWFRNEHELPAS 2132

Query: 3876 HRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
             +YR  +      + +  +  EDSG++IC A N  G       +  K+ P       +  
Sbjct: 2133 DKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVE 2192

Query: 3936 GMKRSEALTQME 3947
             +K +E   + E
Sbjct: 2193 TLKNAEVSLECE 2204



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 39/140 (27%), Positives = 80/140 (57%), Gaps = 5/140 (3%)

Query: 1801 FVQSKASLQL-ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
            FV++ A+LQ  +++  +A + I Q+++      RE++   +   P  I +  GP  ++ G
Sbjct: 2326 FVENVATLQFAKAEPANAGKYICQIKNDGGM--RENMATLMVLEPAVIVEKAGPMTVTVG 2383

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            ++   EC++   P+  + VEWY +GK+L S  +++ S     ++L IL+V  +D+G YT 
Sbjct: 2384 ETCTLECKVAGTPE--LSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTF 2441

Query: 1920 KAINNLGQAVSSIRLNVQSK 1939
            +  NN+G++  +  ++V  +
Sbjct: 2442 QVQNNVGKSSCTAVVDVSDR 2461



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 2/103 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F  + K H +E  +G       E +  P   + WY++ + L SG +Y+ + +  
Sbjct: 4060 VKEPPIF--RKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENF 4117

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
              S+ IL V A D GEY C+A ND G D    +I+ K  P  +
Sbjct: 4118 LTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFV 4160



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 94/442 (21%), Positives = 170/442 (38%), Gaps = 34/442 (7%)

Query: 3778 SATTTAKITCSAKRDI--VLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQ 3835
            S +    IT + K  I  +LES +        + E E G+  D  +    V  PP FI  
Sbjct: 3633 SQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQ--DICEALVSVLEPPYFIEP 3690

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            ++       E    +C+V+    P++RI WY+    L S   Y+  +     SL I  V 
Sbjct: 3691 LEHVEAVIGEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVD 3748

Query: 3896 AEDSGEYICRAVNDFGEDFTKA--TISCKKLPDIILQ--NQVPRGMKRSEALTQMEATIK 3951
              D GEY C+A N  G   + A   I  +KLP    +    V   +    A  +      
Sbjct: 3749 HSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAF-ECRINGS 3807

Query: 3952 KYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLV--EMETTKFECQLA-PVGDPNMKVE 4008
            +     +  +  L   D      FV  + +   L   +    ++ C  + P+G  +    
Sbjct: 3808 EPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASS--- 3864

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
               + K +L ++   P +D   V+++       +SG + C  T    +  T A      +
Sbjct: 3865 ---SAKLILSEHEVPPFFDLKPVSVDLAL---GESGTFKCHVTGTAPIKITWAKDNREIR 3918

Query: 4069 PGIVYDSQLPKHMKSIEKIREMEA-SWQVTPEQVVEESKARC--------PPVFV-SLPD 4118
            PG  Y   L ++  ++  ++  +  + Q T        K  C        PP F+  L  
Sbjct: 3919 PGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEP 3978

Query: 4119 AVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDT 4177
            +  V++ E+ R+ C++ G P+ +V+W  +   I   S++++++ D +   ++      D+
Sbjct: 3979 SRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDS 4038

Query: 4178 GKIEVIXXXXXXXXXXXXXLKV 4199
            G                  LKV
Sbjct: 4039 GDYTCEAHNAAGSASSSTSLKV 4060



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 71/276 (25%), Positives = 117/276 (42%), Gaps = 33/276 (11%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  PVF Q L+ P  VSEG+ + L C ++  G   +R++W   GR +    R    +  G
Sbjct: 5008 KKPPVFDQHLT-PVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFASG 5064

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLED 1293
               L++     AD+G+Y  +A N  GS  T + V + ++  +   T+             
Sbjct: 5065 TAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKK------------ 5112

Query: 1294 AARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK-- 1351
            AA     V   +  +  PQ      +I  VE T      ++   GD    V+W   GK  
Sbjct: 5113 AA-----VDGRLFFVSEPQ------SIRVVEKTTATFIAKVG--GDPIPNVKW-TKGKWR 5158

Query: 1352 PIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV-IAKKDLIL 1410
             +  G R     + D   L++      DSG+Y C A N+ GE  ++  L+V   KK   +
Sbjct: 5159 QLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKI 5218

Query: 1411 ESQHPSGLEKIQYL-EDTSRYKKTDIIDESVTIKPR 1445
            E    + L+K   L +     ++ DI++    + P+
Sbjct: 5219 EGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPK 5254



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 77/352 (21%), Positives = 142/352 (40%), Gaps = 45/352 (12%)

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
            KQ+Q+E     EI  +I  +E  E E +       ++  +  ++P    K ++   V + 
Sbjct: 5279 KQSQEEETHRLEI-EEIERSERDEKEFEELVS--FIQQRLSQTEPVTLIKDIENQTVLKD 5335

Query: 4426 EQARFEVEFD-GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484
              A FE++     P   + WY+    ++ S  F+I     +  L ++   ++D   +  V
Sbjct: 5336 NDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLV 5395

Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
                 G    SA L V E           P++    Q+V +  GQ   +  + +    + 
Sbjct: 5396 C----GPHIASAKLTVIE-----------PAWERHLQDVTLKEGQTCTMTVQFS-VPNVK 5439

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC--VAINSAGEARCDAECV 4602
              W +NG+ ++P  R+K   E   + L I +   +D G+Y C    + ++ E R +AE  
Sbjct: 5440 SEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAE-- 5497

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
                               P +  + +++ +V+E Q+  F C+ V      V WYKG   
Sbjct: 5498 -------------------PIQFTKRIQNIVVSEHQSATFECE-VSFDDAIVTWYKGPTE 5537

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA-YNSAGRVTVAAKLKVT 4713
            +  S+ +        + + I    P+DEG Y  +A     G     A+L +T
Sbjct: 5538 LTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLT 5589



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 36/106 (33%), Positives = 54/106 (50%), Gaps = 2/106 (1%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V + P+FI + +    L  GQS  +EC+I     P +RV WY +G  + +  ++  S   
Sbjct: 1522 VKEPPQFIKKPSPVLVLRNGQSTTFECQITG--TPKIRVSWYLDGNEITAIQKHGISFID 1579

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
            G A   I     E+SG Y C+A N+ G A  SI L V+   + IR+
Sbjct: 1580 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE 1625



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP+F    +      +G+    E  +  +G   + + WF N   +  S +    +   + 
Sbjct: 3028 PPKFVKKLEASKVAKQGESIQLECKI--SGSPEIKVSWFRNDSELHESWKYNMSFINSVA 3085

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I      DSG Y C A N  G A  S  L     +    P FT     +  LK G  
Sbjct: 3086 LLTINEASAEDSGDYICEAHNGVGDASCSTAL-----TVKAPPVFTQKPSPVGALK-GSD 3139

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               +C +     P  ++ W  + + +R+S + K  S      L I   +  D GEY C+A
Sbjct: 3140 VILQCEI--SGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKA 3197

Query: 3227 YNKYGED 3233
             N+ G D
Sbjct: 3198 TNEVGSD 3204



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 40/158 (25%), Positives = 67/158 (42%), Gaps = 8/158 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG   + + W  NG  +  S R          +LEI  +   D+G Y+C   N  G+   
Sbjct: 4557 TGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIENASGKDSC 4616

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            S ++  +     + P F   ++ ++ +  G SA  +C +     P++ + WY     +R 
Sbjct: 4617 SAQILIL-----EPPYFVKQLEPVK-VSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRP 4668

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            +T  K         L       +DSGEY+C+A N  GE
Sbjct: 4669 TTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGE 4706



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 3/101 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F +PL N   V  G    L+C++   G   MRV WF +G+ +    R++  +  G  +
Sbjct: 778  PFFTKPLRNVDSVVNG-TCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT 1277
            L+II     D G +T RA N +GS  +S  + V E    VT
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVT 875



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 2/102 (1%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            +++V + P+F+ +L       +G+S   EC+I   P+  ++V W+ N   L    +Y  S
Sbjct: 3022 QLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPE--IKVSWFRNDSELHESWKYNMS 3079

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
                 A L I     EDSG+Y C+A N +G A  S  L V++
Sbjct: 3080 FINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 3121



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 57/215 (26%), Positives = 83/215 (38%), Gaps = 24/215 (11%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P    PLQ+     EGQ A F CR   V    LKV W+  +K I+ S     T       
Sbjct: 10   PAIITPLQDTVT-SEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ 65

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495
            + I+    EDEG Y   A+N +G+                L  + PE +         HE
Sbjct: 66   LEIAEAYPEDEGTYTFVANNAVGQVSSTA----------NLSLEAPESIL--------HE 107

Query: 2496 RRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555
            R  +E + E +     +    P E+  G  A +   +     P++RF+W+  G E+    
Sbjct: 108  RIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESD 165

Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +          +L+I      D G Y CKA N  G
Sbjct: 166  KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYG 200



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 6/195 (3%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G+ P F  +    VD   G+ A +E  +  TG Q + + W  + + I +  + +  Y   
Sbjct: 4814 GKNPPFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLEN 4871

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +L     DSG Y+C A N+ G+   + +L    K +   P FT  +       +G
Sbjct: 4872 SAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI--KERLIPPSFTKRLSETVEETEG 4929

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
             S   E  V       + + WY N   ++ ++  +       +VL +     +D+G Y C
Sbjct: 4930 NSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTC 4987

Query: 3225 RAYNKYGEDFTRATI 3239
            +  N  G     ++I
Sbjct: 4988 KVSNDAGSALCTSSI 5002



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 29/92 (31%), Positives = 52/92 (56%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F  PL++V ++  G    + +I   G   M++ W K+G+ I AS R+   F  G  SL
Sbjct: 778 PFFTKPLRNVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 835

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           +++ +++ D+G +TCRA ++ G  ++   L V
Sbjct: 836 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 867



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 61/246 (24%), Positives = 110/246 (44%), Gaps = 42/246 (17%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            ++V +    +    +I+  +G    L+ +    G + +  +WF +G+ +  G +++ +  
Sbjct: 1238 LSVKEPATITEEAVSIDVTQGDPATLQVKFS--GTKEITAKWFKDGQELTLGSKYKISVT 1295

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYL 1424
                 L ++S   +DSG YT +  N +G   +SC  R I   DLI+    PS  +K+   
Sbjct: 1296 DTVSILKIISTEKKDSGEYTFEVQNDVGR--SSCKAR-INVLDLIIP---PSFTKKL--- 1346

Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484
                  KK D      +IK  F+     +E ++ G H        P++     ++WFK+ 
Sbjct: 1347 ------KKMD------SIKGSFI----DLECIVAGSH--------PIS-----IQWFKDD 1377

Query: 1485 QPVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            Q ++   +++   HD     L+I  L   DSG YTC A N  G ++ S  LT +     V
Sbjct: 1378 QEISASEKYKFSFHD-NTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFV 1436

Query: 1544 RSTQNE 1549
               Q++
Sbjct: 1437 EKPQSQ 1442



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 3/93 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP FT ++K+   +  G  V  +C+V   G P + + WFH G   ++G +  T       
Sbjct: 4346 PPSFTRKLKETNGL-SGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTC 4402

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            AL ++ +   D+G+YTC ATN  GS   +A +T
Sbjct: 4403 ALTVNMLEESDSGDYTCIATNMAGSDECSAPLT 4435



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 32/146 (21%), Positives = 73/146 (50%), Gaps = 3/146 (2%)

Query: 1258 LGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT-VMQAPQFSRA 1316
            LGS +  ++   +    I++  + +      ++  D  R + + R ++  ++  P F++ 
Sbjct: 1286 LGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKK 1345

Query: 1317 LHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVY 1376
            L  +++++G+ + LEC +   G   + ++WF + + I    +++ ++  +   L++  + 
Sbjct: 1346 LKKMDSIKGSFIDLECIV--AGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLE 1403

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRV 1402
              DSG YTC ATN+ G    S  L V
Sbjct: 1404 GTDSGTYTCSATNKAGHNQCSGHLTV 1429



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 52/240 (21%), Positives = 95/240 (39%), Gaps = 16/240 (6%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            VD++E      E   +  G   + ++W  +GK I  S      +   +    I      D
Sbjct: 1815 VDVTEKDPMTLEC--VVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQD 1872

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            SG Y+ +  N +G +     L  +D++    P FT  +  ++ +  G S H EC V    
Sbjct: 1873 SGQYTFKVENDFGSSSCDAYLRVLDQN--IPPSFTKKLTKMDKVL-GSSIHMECKV--SG 1927

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
               +  +W+ +G+ +  S + + V     V L++   +  D+  Y C+  N  G+D    
Sbjct: 1928 SLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDD---- 1983

Query: 3238 TINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEG 3297
               C    G+      P  L K    +++  +  +  +     PP  I   +D  +LV G
Sbjct: 1984 --AC---SGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSG 2038



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F   +   TV E E V+  C V+  E   +RI+W + G+ +    R    +  G   
Sbjct: 5010 PPVFDQHLTPVTVSEGEYVQLSCHVQGSEP--IRIQWLKAGREIKPSDRCSFSFASGTAV 5067

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            L++  V   DSG+Y+C+A N  G D TK+ ++ K  P +
Sbjct: 5068 LELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV 5106



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 52/201 (25%), Positives = 76/201 (37%), Gaps = 13/201 (6%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G   M + WF +GK I AS R R  +  G   LEI+     D+G ++CRATN  G  + S
Sbjct: 803  GSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSS 862

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD-DPDMKIEWYHNGQPMRH 3194
              L        + P F T      G KD       C          + I W+   + +  
Sbjct: 863  GAL-----IVQEPPSFVTK----PGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVS 913

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK-GGVYLESLQ 3253
                    +     L++   +  DSG Y C+  N  G      + N + K    ++E L+
Sbjct: 914  GGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG--VECSANLFVKEPATFVEKLE 971

Query: 3254 PDSLAKIRELESLQGAQQQTP 3274
            P  L K  +   L      TP
Sbjct: 972  PSQLLKKGDATQLACKVTGTP 992



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 59/279 (21%), Positives = 107/279 (38%), Gaps = 13/279 (4%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            +PP+F Q        +G +   + ++ G P   V W + +  +    K+ +    +  D 
Sbjct: 3121 APPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKI--TSKHFDT 3178

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
            +L I  +   D GEY C A N+ G   CS  ++ +                 + + VE +
Sbjct: 3179 NLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTL--IGDAVELR 3236

Query: 190  AY--GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247
            A   G Q  +    +   +V   +     S  D          L+  S   S + +Y+ +
Sbjct: 3237 AIVEGFQPISVVWLKDRGEVIRESENTRISFID------NIATLQLGSPEASNSGKYICQ 3290

Query: 248  SDVQIST-EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
                    E    L  + P +I +KP    +  G     +  ++G P     WFK+G+ L
Sbjct: 3291 IKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGREL 3350

Query: 307  INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               +KH I   +   +L++   + SD G Y+   +N  G
Sbjct: 3351 SADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVG 3389



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 37/114 (32%), Positives = 54/114 (47%), Gaps = 3/114 (2%)

Query: 631  DRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR 690
            DR+ PP  FI  LK V A+ G  +  E R+   G   + + W ++G  I +  +  S F 
Sbjct: 3401 DRIVPP-SFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFS 3457

Query: 691  FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
                +L++  L   D+G YTC A +  G  E  AVL V    + E+T    E L
Sbjct: 3458 ENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVL 3511



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 77/360 (21%), Positives = 146/360 (40%), Gaps = 39/360 (10%)

Query: 3825 IVST--PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            +VST  PP F+T+++       + V  +C+V     P++ + WY+    L     YRT +
Sbjct: 2737 LVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYF 2794

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEA 3942
                 +L    V   DSGEY C+A N  G   +K      ++ +  L     R +K  E 
Sbjct: 2795 TNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVF---RIQERQLPPSFARQLKDIEQ 2851

Query: 3943 LTQMEATIK-----KYTSEVYLTEDDLYDVDKKQ-PPRFVTQIQS----QTSLVEMETTK 3992
               +  T+          +V    D +   D +     FV  + +    QT L    + +
Sbjct: 2852 TVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDL--SHSGQ 2909

Query: 3993 FECQLA-PVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRAT 4051
            + C  + P+G  +       + +    + + +P +D   V+++   V   +S ++ C  T
Sbjct: 2910 YSCSASNPLGTASS------SARLTAREPKKSPFFDIKPVSID---VIAGESADFECHVT 2960

Query: 4052 NLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA-SWQVTPEQVVEESKARC- 4109
                M  T +      +PG  Y      +   +  ++  +  S Q T +   +  K  C 
Sbjct: 2961 GAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCS 3020

Query: 4110 -------PPVFVSLPDAVTV-EEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
                   PP FV   +A  V ++GE  +  C+++G P+ +V W  N + +    +Y +++
Sbjct: 3021 AQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF 3080



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 2/92 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F R L ++  + G +V LECR+   G   + V WF +G  I +G + + ++  +   L
Sbjct: 3406 PSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 3463

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L  + P D+G+YTC A N  G    S  L V
Sbjct: 3464 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 3495



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 71/322 (22%), Positives = 126/322 (39%), Gaps = 34/322 (10%)

Query: 1531 SCRLTCRSTTDIV---RSTQNEAGLEQIQVLEDR-SKYHRTDMVDEVTTQAPICTTSLKN 1586
            +C +T ++ T ++   ++  N+AGL   +V  D  S    + +V +   + P+    L  
Sbjct: 4960 NCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTP 5019

Query: 1587 VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPED 1646
            V + EG+       +       ++++W    + +K   R + +   G   L++      D
Sbjct: 5020 VTVSEGEYVQLSCHV--QGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKAD 5077

Query: 1647 SGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV 1706
            SG Y C+A N  G   T     +  K ++   ++      RL                  
Sbjct: 5078 SGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRL------------------ 5119

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
                  F    + IRV E   A F A++   GDP   V+W +             +H  G
Sbjct: 5120 -----FFVSEPQSIRVVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLNQGGRVFIHQKG 5172

Query: 1767 YVA-LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-QSKASLQLESQHESALQKIQQL 1824
              A L ++     DSG Y C A NE GE  ++  L V + K   ++E    + L+K   L
Sbjct: 5173 DEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPIL 5232

Query: 1825 EDSSRYQRREDV-EVAVNQAPR 1845
            +  +  +   D+ E+  N  P+
Sbjct: 5233 KKGAGEEEEIDIMELLKNVDPK 5254



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 67/241 (27%), Positives = 101/241 (41%), Gaps = 35/241 (14%)

Query: 763  EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASS--RIT 820
            +E     P  I PLQD     EG+ A F+ +   VS   ++V WY   + I  S   R+T
Sbjct: 3    QEMPVYPPAIITPLQDT-VTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMT 58

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRY 880
              F   Y  L I     ED G+YT  A N +G+  STA++ + A  +      I  +R  
Sbjct: 59   Q-FEDTY-QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPES------ILHER-- 108

Query: 881  IEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDST 940
            IE+                    E    P  K  I + + +  G  A F   ++   +  
Sbjct: 109  IEQEIEM----------------EMKAAPVIKRKI-EPLEVALGHLAKFTCEIQSAPN-- 149

Query: 941  LRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000
            +R +W K GR +  S + +   +    +L I    V D G YTC+A N  G  + +A LT
Sbjct: 150  VRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT 209

Query: 1001 I 1001
            +
Sbjct: 210  V 210



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 2/96 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F+  L+ + A  G  +  + ++   G P + + W K    +  +  + + F     +
Sbjct: 2743 PPYFVTELEPLEAAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTNNVAT 2800

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L    +NI DSGEYTC+A ++ G A +K V  +  R
Sbjct: 2801 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 2836



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 31/108 (28%), Positives = 55/108 (50%), Gaps = 3/108 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   ++    +K+  F  +E ++   G   ++V W KD   ++ SS+    F    
Sbjct: 3968 EPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDSV 4025

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014
              L + +++V D+G YTC A+NA G A++S +L  V +  I  +  HP
Sbjct: 4026 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLK-VKEPPIFRKKPHP 4072



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 2/107 (1%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V V + P F+ +++    +  G+SA   C+++    P ++V W+ N K L   +  R   
Sbjct: 396  VTVREPPSFVKKVDPSYLMLPGESARLHCKLKG--SPVIQVTWFKNNKELSESNTVRMYF 453

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
                A LDI  V  EDSG Y+C+A+N++G    S  + ++   S I+
Sbjct: 454  VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIK 500



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 2/98 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP FT P++++    N     + ++   G   +RV W ++G  I AS+R       G  +
Sbjct: 777  APFFTKPLRNVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            L +  V+  D+G +TCRA N +G   +S  L VQ   S
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPS 872



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 82/385 (21%), Positives = 153/385 (39%), Gaps = 28/385 (7%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            ++P FT     IE L+E +     A +  T  P  ++ W+ +   L++G +++TF     
Sbjct: 1056 ESPYFTKEFKPIEVLKEYD-VMLLAEVAGT--PPFEITWFKDNTILRSGRKYKTFIQDHL 1112

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGME-GTIDKIA 3536
            V L+I      D+GEY CR  N  G ++ +A + ++   + I + +    +  GT    A
Sbjct: 1113 VSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQA 1172

Query: 3537 ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
             L+G      T   +++     E T   +  +  EN+ A      I V      V    N
Sbjct: 1173 TLKGSLPITVTWLKDSD-----EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKN 1227

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGG--VYQRDAGLYTCKATN---------RHG-EATVS 3644
               +   S + ++ +   +  E     V Q D      K +          + G E T+ 
Sbjct: 1228 DAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLG 1287

Query: 3645 CKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHK---REEITIEDEKPNPPRFTVEI 3701
             K ++     + +   + +  K   E   +++  + +   +  I + D    P  FT ++
Sbjct: 1288 SKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPP-SFTKKL 1346

Query: 3702 KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIY 3761
            K  +D  +G  +  +C V   G   + I WF + +  +   +           L+I  + 
Sbjct: 1347 K-KMDSIKGSFIDLECIV--AGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLE 1403

Query: 3762 ARDAGEYTCRATNKWGSATTTAKIT 3786
              D+G YTC ATNK G    +  +T
Sbjct: 1404 GTDSGTYTCSATNKAGHNQCSGHLT 1428



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 51/228 (22%), Positives = 95/228 (41%), Gaps = 29/228 (12%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I+ L + V  EG    F+C V  +    LK+ W+  +K +     ++ T       L+I 
Sbjct: 13   ITPLQDTVTSEGQPARFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIA 69

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLA 2896
              Y ED G YT  A N+ G  +++ +L     ++I             E +EQ  E  + 
Sbjct: 70   EAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILH-----------ERIEQ--EIEME 116

Query: 2897 KGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQ 2956
                P +     P     + +A  H          +   E ++ P+++ +W+  G+ + +
Sbjct: 117  MKAAPVIKRKIEP-----LEVALGHL--------AKFTCEIQSAPNVRFQWFKAGREIYE 163

Query: 2957 GSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCT 3004
              +  + S     +L+++     D G YTCKA N+ G    ++T+  T
Sbjct: 164  SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 211



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 58/289 (20%), Positives = 110/289 (38%), Gaps = 7/289 (2%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F +   +     G     +  +RG+    V+W + +  + E  K  M ++   G   
Sbjct: 588 PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSN--GVAV 645

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
           L+I  +     G+YTC A N+ G       +  +                    T+E+  
Sbjct: 646 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTV 705

Query: 191 YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
            GT     +  +  + +  +     S  ++     F    L +           VG S  
Sbjct: 706 AGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSC 765

Query: 251 QIS-TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
           + + T +DR + P     +    RN         +   +++G+   RV+WFK+G+ +  S
Sbjct: 766 ETTFTVLDRDIAPFFTKPL----RNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAAS 821

Query: 310 NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           +++ I       +L +     +D+G++T  A N  G   +SG L V+ P
Sbjct: 822 DRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEP 870



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 2/111 (1%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            PQFI+    +  L+ G++  FE Q+T    P +RV WY DG  ITA  +    F  G  +
Sbjct: 1526 PQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 1583

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRY 880
              I   R E++G+Y   A N  G A  +  ++V    T   +L   E  +Y
Sbjct: 1584 FQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKY 1634



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 51/219 (23%), Positives = 86/219 (39%), Gaps = 6/219 (2%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            +P KPP+F + + P  V E E  +      G     I+W +    IK S        S  
Sbjct: 5006 EPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGT 5065

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG----RGGIVPPSFTLTA- 4520
            ++L +R V   DS  +   A N  G+    + + +++K        +  +    F ++  
Sbjct: 5066 AVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEP 5125

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG-KKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            Q++ V          KV G    +V W K   +++    R  I ++     L I +    
Sbjct: 5126 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKT 5185

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKA 4618
            DSG Y CVA N  GE   +    V     ++K +   +A
Sbjct: 5186 DSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRA 5224



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F  P+++  S+  G     + ++   G   +RV W KDG+ + AS R    F  G  +
Sbjct: 778  PFFTKPLRNVDSVVNGT-CRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I  V ++DAG++TCRA N++G   +S  L +
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 867



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 45/193 (23%), Positives = 81/193 (41%), Gaps = 8/193 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    +  V +S G  A  +  L   G   + + W+     +  +   +  +   + 
Sbjct: 4625 PPYFVKQLEP-VKVSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVA 4681

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L        DSG Y C+A N  G+   S  L  V + K   P F+  +++++    G  
Sbjct: 4682 TLVFNQVDINDSGEYICKAENSVGEVSASTFL-TVQEQK-LPPSFSRQLRDVQETV-GLP 4738

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              F+C  +   +P + + WY +G+P++ S  ++T        L+I  T    +G+Y C A
Sbjct: 4739 VVFDC-AISGSEP-ISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTA 4796

Query: 3227 YNKYGEDFTRATI 3239
             N  G   + A +
Sbjct: 4797 TNPIGSASSSARL 4809



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)

Query: 3268 GAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPH 3327
            G+   + +    EPP F+ ++     ++ G+SA    +L     P ++V WF N K+L  
Sbjct: 388  GSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSE 445

Query: 3328 GHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +  R +      ILDI     E+SG Y C A N +G DS    +
Sbjct: 446  SNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 490



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 48/192 (25%), Positives = 83/192 (43%), Gaps = 11/192 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F     D++ +  GQ    +A++   G + + + W    + I    +I+  ++ G+ 
Sbjct: 588  PPTFVKKVDDLIALG-GQTVTLQAAV--RGSEPISVTWMKGQEVIREDGKIKMSFSNGVA 644

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            VL I   + +  G Y+C A N+ G ++ SV  E + K   +       IQ    +  G  
Sbjct: 645  VLIIPDVQISFGGKYTCLAENEAG-SQTSVG-ELIVKEPAKIIERAELIQ----VTAGDP 698

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A  E TV     P++K +WY +G+P+  S + +         L     + HDSG+Y    
Sbjct: 699  ATLEYTVAGT--PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEI 756

Query: 3227 YNKYGEDFTRAT 3238
             N+ G      T
Sbjct: 757  SNEVGSSSCETT 768



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 35/104 (33%), Positives = 48/104 (46%), Gaps = 3/104 (2%)

Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG 1500
            T+ P F TR     N + G  V  ECK+       + V WF  G  ++ G +++      
Sbjct: 4344 TVPPSF-TRKLKETNGLSGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDN 4400

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVR 1544
              AL +  L   DSG YTC A N+ G+DE S  LT R     V+
Sbjct: 4401 TCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQ 4444



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 59/230 (25%), Positives = 100/230 (43%), Gaps = 32/230 (13%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS--RITTFFNFGY 966
            P   TP++D ++  EG  A F+ R   +  + L+V W    + ++ S   R+T F +   
Sbjct: 10   PAIITPLQDTVT-SEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT-- 63

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDA 1026
              L I      D G YT  A NA+GQ +++ANL++   + I+ E                
Sbjct: 64   YQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHE---------------- 107

Query: 1027 SRYSKRTEEEVKITQK-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQ 1085
             R  +  E E+K      R + PL    ++  G  A F   +  QS   +  +W+  G++
Sbjct: 108  -RIEQEIEMEMKAAPVIKRKIEPL----EVALGHLAKFTCEI--QSAPNVRFQWFKAGRE 160

Query: 1086 ITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            I  +++          +L+I   +  D G YT  A N  G    +A++TV
Sbjct: 161  IYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 2/92 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F++ L  ++ V G+++H+EC++   G   +  +WF +GK I T  ++R       V+L
Sbjct: 1902 PSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSL 1959

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            ++ ++  ED+  YTC+ +N  G+   S  L V
Sbjct: 1960 EVNNLELEDTANYTCKVSNVAGDDACSGILTV 1991



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 3/103 (2%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V+  + P F+T+L  P + + G S   +C++   P+  + V WY     L+    YRT  
Sbjct: 2738 VSTLEPPYFVTELE-PLEAAVGDSVSLQCQVAGTPE--ITVSWYKGDTKLRPTPEYRTYF 2794

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
                A L    V   DSGEYTCKA N++G A S     +Q ++
Sbjct: 2795 TNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ 2837



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 34/98 (34%), Positives = 45/98 (45%), Gaps = 2/98 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F K     E  +G  VHLE  L     P   V WY + R ++ G ++K   +  
Sbjct: 4060 VKEPPIFRKKPHPIETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENF 4117

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
              ++ IL   A D G Y CKATN VG      S+ + A
Sbjct: 4118 LTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA 4155



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 55/256 (21%), Positives = 104/256 (40%), Gaps = 24/256 (9%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYN-GKTIEASHRIRTVYAFGM 3105
            PP F     DI  +  G+    + ++   G + + + WF + G+ +  S  I   Y+  +
Sbjct: 4156 PPRFVKKLSDISTVV-GKEVQLQTTI--EGAEPISVVWFKDKGEIVRESDNIWISYSENI 4212

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK--D 3163
              L+    +  ++G Y+C+  N  G  E    L  ++ +        T ++  E +K   
Sbjct: 4213 ATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPA--------TIVEKPESIKVTT 4264

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV-LDIAYTQNHDSGEY 3222
            G +   ECTV     P++  +W+ +G+ +    + K +S F  V  L I      DSG Y
Sbjct: 4265 GDTCTLECTV--AGTPELSTKWFKDGKELTSDNKYK-ISFFNKVSGLKIINVAPSDSGVY 4321

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282
                 N  G+D   A++       V   ++ P    K++E   L G+           PP
Sbjct: 4322 SFEVQNPVGKDSCTASLQ------VSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPP 4375

Query: 3283 KFITQIQDVTKLVEGQ 3298
              ++   +  ++  G+
Sbjct: 4376 ISVSWFHEGNEISSGR 4391



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 54/229 (23%), Positives = 89/229 (38%), Gaps = 15/229 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP FT   K+   +S   +   E  +   G   + + WF+ G  I +  + +T       
Sbjct: 4346 PPSFTRKLKETNGLSGSSVV-MECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTC 4402

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L +   + +DSG Y+C ATN  G  E S  L     +  + P F      ++ L  G +
Sbjct: 4403 ALTVNMLEESDSGDYTCIATNMAGSDECSAPL-----TVREPPSFVQKPDPMDVL-TGTN 4456

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              F  T +    P   + W+     +    R     +     L++       SGEY C  
Sbjct: 4457 VTF--TSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIV 4514

Query: 3227 YNKYGEDFTRATINCYGKG-GVYLESLQPDSLAKIRELESLQGAQQQTP 3274
             N+ G+     T + Y K    +++ L   S+ K + L  L+G    TP
Sbjct: 4515 SNEAGK--ASCTTHLYIKAPAKFVKRLNDYSIEKGKPL-ILEGTFTGTP 4560



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            + P F T L+  +  V G  V L+ QV     P + + W+K    L      ++ F   +
Sbjct: 2742 EPPYFVTELEPLEAAV-GDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYFTNNV 2798

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             TL  N +  +DSG YTCKA N +G A S    +I++R
Sbjct: 2799 ATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 2836



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 71/287 (24%), Positives = 117/287 (40%), Gaps = 35/287 (12%)

Query: 3370 ANLKCTSKENLILDSQLPRGM-EGGLEKLQTLEDSMVRRKDTSVE-EEKGKAPVFTVPLS 3427
            +N + T K N ++      GM + GL   +   D+      +S+  +E  K PVF   L+
Sbjct: 4959 SNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 5018

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
             +  + EGE       +  ++   ++++W   G+ +K   R       G  +LE+     
Sbjct: 5019 PV-TVSEGEYVQLSCHVQGSEP--IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAK 5075

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             DSG+Y+C+A N  G   T + + ++ K         P     T  K AA++G    V  
Sbjct: 5076 ADSGDYVCKASNVAGSDTTKSKVTIKDK---------PAVAPAT--KKAAVDGRLFFV-- 5122

Query: 3548 LTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH-NGKPLLTGSRV 3606
                          + P  + + E ++A F  ++    D    V+W     + L  G RV
Sbjct: 5123 --------------SEPQSIRVVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLNQGGRV 5166

Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
                      LEI    + D+GLY C A N HGE   +  LQV  R+
Sbjct: 5167 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERK 5213



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 51/207 (24%), Positives = 79/207 (38%), Gaps = 12/207 (5%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            I I E    P F +      V+EG+  +  C V G     + W    R+I+         
Sbjct: 5002 IVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSF 5061

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV-APK--------- 492
              SG   L + +V  +DSG   C A N +G    + ++ + +K  V  A K         
Sbjct: 5062 -ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLF 5120

Query: 493  FVERFSTLNVREGEPVVLNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIP 551
            FV    ++ V E       A+  G P P + W K     +     + IH  G  + L+I 
Sbjct: 5121 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIR 5180

Query: 552  RAKASDAAWYQCTAQNVAGSTATRARL 578
                +D+  Y+C A N  G   +   L
Sbjct: 5181 DTTKTDSGLYRCVAFNEHGEIESNVNL 5207



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 56/227 (24%), Positives = 95/227 (41%), Gaps = 27/227 (11%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            ++ P+F  HL     + EG++V L   V+  ++P ++I+W K G  +    R   +F  G
Sbjct: 5008 KKPPVFDQHLTPVT-VSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASG 5064

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXX 2758
               L +  +   DSG Y CKA+N+ G   + + + I+D+   +  +    ++D  G L  
Sbjct: 5065 TAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKP-AVAPATKKAAVD--GRL-- 5119

Query: 2759 XXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN-KPLP 2817
                             F+S   +I   E     F   V    DP   ++W     + L 
Sbjct: 5120 ----------------FFVSEPQSIRVVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLN 5161

Query: 2818 SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
             G R           L+I  T + DSG+Y C A N  G   ++ +L+
Sbjct: 5162 QGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQ 5208



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 4/111 (3%)

Query: 1439 SVTIK--PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            +VT++  P FV +      ++ G+     CKL+      ++V WFKN + ++  +  R  
Sbjct: 395  TVTVREPPSFVKKVDPSYLMLPGESARLHCKLKG--SPVIQVTWFKNNKELSESNTVRMY 452

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
                   LDI D+  EDSG Y+C AVN VG+D  S  +  +     +++ +
Sbjct: 453  FVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLE 503



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 30/83 (36%), Positives = 45/83 (54%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+PL+N+D++  G T   DC++   G   ++V WF++ K I  S R       G  S
Sbjct: 778  PFFTKPLRNVDSVVNG-TCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V   D G + CRA+N +G
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVG 857



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 38/122 (31%), Positives = 63/122 (51%), Gaps = 8/122 (6%)

Query: 3268 GAQQQTPSTPSAEPPKFITQIQDVTKLVE-GQSAHFEARLVPVDDPDLKVEWFYNGKKLP 3326
            G+   T      EPPKF+ +++  +K+V+ G S+  E ++     P+++V WF N  +LP
Sbjct: 2074 GSDSCTTMLLVTEPPKFVKKLE-ASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELP 2130

Query: 3327 HGHRYR-TFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQ 3385
               +YR TF D  + ++ +     E+SG++ C A N  G  ST  + K   KE  +  S 
Sbjct: 2131 ASDKYRMTFID-SVAVIQMNNLSTEDSGDFICEAQNPAG--STSCSTKVIVKEPPVFSSF 2187

Query: 3386 LP 3387
             P
Sbjct: 2188 PP 2189



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 27/87 (31%), Positives = 47/87 (54%), Gaps = 3/87 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P+F +   +P    +G ++HLEC L+  G P   V W+ + R +  G ++K   +  
Sbjct: 4061 KEPPIF-RKKPHPIETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENF 4117

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGS 1260
              ++ I++  +AD GEY  +A N +GS
Sbjct: 4118 LTSIHILNVDAADIGEYQCKATNDVGS 4144



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 3/101 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F  +L     LS G S   EC++  Y  P + V W+  G  + SG +Y+T+      A
Sbjct: 4347 PSFTRKLKETNGLS-GSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 4403

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            L +  +   DSG+YTC A N  G    S  L V+   S ++
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQ 4444



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 4/119 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F      P     G+SA +EC +     P ++V W  + + ++SG +Y+ S     A 
Sbjct: 4817 PPFFDIRLAPVDAVVGESADFECHVTG-TQP-IKVSWAKDSREIRSGGKYQISYLENSAH 4874

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
            L +L V   DSG+YTC A+N +G+   + +LN+  KE +I  S  +   E ++  E +S
Sbjct: 4875 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI--KERLIPPSFTKRLSETVEETEGNS 4931



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 3/93 (3%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F +PL+++  +  G     + ++   S P MRV W+KDG+ I AS R    F  G  S
Sbjct: 778 PFFTKPLRNVDSVVNG-TCRLDCKIAG-SLP-MRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           L I+ +   DAG++T RA N +G   S+ ++ V
Sbjct: 835 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 867



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 3/91 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P FT  ++ N+D    G    DC++   G   MR+ WF +G+  A   R       G  +
Sbjct: 778  PFFTKPLR-NVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L+I  +   DAG +TCRATN  GS  ++  +
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVGSKDSSGAL 865



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 3/147 (2%)

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV-EESEGVRFECRVEPKEDPKLR 3862
            SG  I +L     +   K    V  PP+FI +     V    +   FEC++     PK+R
Sbjct: 1500 SGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGT--PKIR 1557

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            + WY +G  + +  ++   +  G  +  I     E+SG Y+C A ND G       +  K
Sbjct: 1558 VSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 1617

Query: 3923 KLPDIILQNQVPRGMKRSEALTQMEAT 3949
            + P  I + +    +K S+   + E T
Sbjct: 1618 EPPTFIRELKPVEVVKYSDVELECEVT 1644



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  LK  + L  G  V +E +V     P + + WF  G  +++G + ++T       
Sbjct: 4347 PSFTRKLKETNGL-SGSSVVMECKVYG--SPPISVSWFHEGNEISSGRKYQTTLTDNTCA 4403

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L++N L   DSG YTC ATN+ G    +A + + +
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE 4438



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 3/117 (2%)

Query: 1160 SKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS 1219
            +KF   + Q E I   KP F++ L  P   +  K +HLEC+++   D  + V W  +G+ 
Sbjct: 292  NKFGADICQAELIIIDKPHFIKELE-PVQSAINKKVHLECQVDE--DRKVTVTWSKDGQK 348

Query: 1220 VTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276
            +  G  +K  ++     L+I  A   D+G Y   A N  GS+  SA V V E    V
Sbjct: 349  LPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFV 405



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F+  LK  N I+ G S   E RV   + ++  V W+ +G +I S  + Q+        
Sbjct: 3406 PSFIRKLKDVNAIL-GASVVLECRVSGSAPIS--VGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
            L+++ +   D+G+YT VA N AG  + SA +TV+   S +
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFE 3502



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 3/104 (2%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ + + P F+ QL  P K+S G SA  +C++   P+  + V WY     L+    Y+  
Sbjct: 4619 QILILEPPYFVKQLE-PVKVSVGDSASLQCQLAGTPE--IGVSWYKGDTKLRPTTTYKMH 4675

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
                 A L    V   DSGEY CKA N++G+  +S  L VQ ++
Sbjct: 4676 FRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK 4719



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 54/232 (23%), Positives = 92/232 (39%), Gaps = 31/232 (13%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            PVF   +  + V+E +       +   G   +R++WL+ G  I+ S+R +     G   L
Sbjct: 5011 PVFDQHLTPVTVSEGEYVQLSCHV--QGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVL 5068

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             ++ V   DSG Y C+A N  G   T S + ++ K ++   ++  +   ++  + +    
Sbjct: 5069 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEP--- 5125

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK--VLQ 1888
               + + V       FI ++ G                    DP   V+W   GK   L 
Sbjct: 5126 ---QSIRVVEKTTATFIAKVGG--------------------DPIPNVKW-TKGKWRQLN 5161

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             G R         A L+I      DSG Y C A N  G+  S++ L V  ++
Sbjct: 5162 QGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERK 5213



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 51/242 (21%), Positives = 99/242 (40%), Gaps = 25/242 (10%)

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            D+ + + P  +  P       EGQ   F+C+   V+ ++LKV W+   + +     FR  
Sbjct: 2    DQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMT 58

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQ 1556
                   L+I +   ED G YT  A N VG    +  L+  +   I+        +EQ  
Sbjct: 59   QFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHER-----IEQEI 113

Query: 1557 VLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
             +E ++              AP+    ++ +E+  G  A F   +   S   ++ +W+  
Sbjct: 114  EMEMKA--------------APVIKRKIEPLEVALGHLAKFTCEI--QSAPNVRFQWFKA 157

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE-AVTSGIAIVHSKKSI 1675
             + +    + +  ++    +L+I+     D G YTC+A N  G  + T+ + +  +    
Sbjct: 158  GREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPT 217

Query: 1676 YL 1677
            +L
Sbjct: 218  FL 219



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 30/103 (29%), Positives = 52/103 (50%), Gaps = 5/103 (4%)

Query: 1305 ITVMQAPQFSRALH-NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV + P F + +  +   + G +  L C+L+  G   ++V WF N K +   +  R  +
Sbjct: 396  VTVREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYF 453

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
                  LD+  V  EDSG Y+C+A N +G    SC+  ++ K+
Sbjct: 454  VNSEAILDITDVKVEDSGSYSCEAVNDVGS--DSCSTEIVIKE 494



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 2/154 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP FI ++K   V +   V  EC V     P   + W +N + + S  +Y     + 
Sbjct: 1616 VKEPPTFIRELKPVEVVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTLTDRVS 1673

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945
              +L I      D+GEY C   N+ G       ++ K+ P  I + +    + +S A  Q
Sbjct: 1674 VFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQ 1733

Query: 3946 MEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQI 3979
                     S  +L +D + D D      FV  +
Sbjct: 1734 STVAGSPPISITWLKDDQILDEDDNVYISFVDSV 1767



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 28/100 (28%), Positives = 56/100 (56%), Gaps = 2/100 (2%)

Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            GVQ+ P F   L+   ++V+ Q  +   + +    P +K+ W+K+   +   ++ + +F 
Sbjct: 3965 GVQEPPRFIKKLEP-SRIVK-QDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFV 4022

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              +  L +++L  +DSG YTC+A N  G A S+ S+K+++
Sbjct: 4023 DSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE 4062



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 27/101 (26%), Positives = 54/101 (53%), Gaps = 3/101 (2%)

Query: 3826 VSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP+FI +++ S  V++ E  R+EC++     P++++ WY++   +    ++R  +  
Sbjct: 3966 VQEPPRFIKKLEPSRIVKQDEFTRYECKIGGS--PEIKVLWYKDETEIQESSKFRMSFVD 4023

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L++  +  EDSG+Y C A N  G   +  ++  K+ P
Sbjct: 4024 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 4064



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 5/111 (4%)

Query: 1292 EDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK 1351
            +D+   + QV  D TV   P F+R L     + G++V +EC++   G   + V WF  G 
Sbjct: 4331 KDSCTASLQV-SDRTV--PPSFTRKLKETNGLSGSSVVMECKVY--GSPPISVSWFHEGN 4385

Query: 1352 PIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             I +G +++     +  AL +  +   DSG YTC ATN  G    S  L V
Sbjct: 4386 EISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 4436



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 31/101 (30%), Positives = 55/101 (54%), Gaps = 4/101 (3%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            +T++++K  PP F+ +++D +    G PV FDC +   G   + + W+ +G+P      V
Sbjct: 4713 LTVQEQKL-PPSFSRQLRD-VQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNV 4768

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             T        L+I       AG+Y+C ATN  GSA+++A++
Sbjct: 4769 QTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 54/213 (25%), Positives = 85/213 (39%), Gaps = 39/213 (18%)

Query: 924  GGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYT 983
            G  A FE  +   G   ++V W KD R + +  +    +      LT+  V   D+G YT
Sbjct: 4832 GESADFECHVT--GTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYT 4889

Query: 984  CRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKP 1043
            C A N +G+ + +A L I  K+ +I  S                 ++KR  E V+ T   
Sbjct: 4890 CYAVNEVGKDSCTAQLNI--KERLIPPS-----------------FTKRLSETVEET--- 4927

Query: 1044 RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVAL 1103
                         EG S   E RV     +  TV WY N  +I   +  +       + L
Sbjct: 4928 -------------EGNSFKLEGRVAGSQPI--TVAWYKNNIEIQPTSNCEITFKNNTLVL 4972

Query: 1104 DIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             +      D+G+YT    N AG A  ++S+ ++
Sbjct: 4973 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 5005



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 51/220 (23%), Positives = 93/220 (42%), Gaps = 26/220 (11%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P  +SEG+     C ++   +P +R++W   G+ ++   R   S   G A L++  V   
Sbjct: 5019 PVTVSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKA 5076

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDS 1972
            DSG+Y CKA N  G   +  ++ ++ K + +  +  ++A++   +   + +  R V+  +
Sbjct: 5077 DSGDYVCKASNVAGSDTTKSKVTIKDKPA-VAPATKKAAVDGRLFFVSEPQSIRVVEKTT 5135

Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
                    G PI N + T+G                   +W    R + QG R       
Sbjct: 5136 ATFIAKVGGDPIPNVKWTKG-------------------KW----RQLNQGGRVFIHQKG 5172

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
                L+I      D+G Y C A N  GE  +  +++VD +
Sbjct: 5173 DEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 5212



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 3/101 (2%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F   L     +  G +   +C+I       MRV W+ +GK + +  RYR +   G A
Sbjct: 777  APFFTKPLRNVDSVVNG-TCRLDCKIAG--SLPMRVSWFKDGKEIAASDRYRIAFVEGTA 833

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            +L+I+ V   D+G +TC+A N++G   SS  L VQ   S +
Sbjct: 834  SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFV 874



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 29/103 (28%), Positives = 56/103 (54%), Gaps = 5/103 (4%)

Query: 1435 IIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494
            ++D++  I P F  +   ++ V+ G  +H ECK+       +  +WFK+G+ ++   ++R
Sbjct: 1895 VLDQN--IPPSFTKKLTKMDKVL-GSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYR 1949

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
             +     V+L++ +L  ED+  YTC+  N+ G D  S  LT +
Sbjct: 1950 LVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 1992



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 65/283 (22%), Positives = 112/283 (39%), Gaps = 51/283 (18%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F  ++          +  EC+V       +  +W+++GK + +  +YR V     VS
Sbjct: 1901 PPSFTKKLTKMDKVLGSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL----QNQVPRGMKRSEALT 3944
            L++  +  ED+  Y C+  N  G+D     ++ K+ P  ++    Q  +P      +A+ 
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAIL 2018

Query: 3945 Q--MEATIKKYTSEVYLTED--------------DLYDVDKKQPPRFVTQIQSQ------ 3982
            +      IK +  +V L                 +LY VD  +  ++   + +       
Sbjct: 2019 KGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSC 2078

Query: 3983 -TSLVEMETTKF-----ECQLAPVGD-----------PNMKVEWFFNGK--PLLHKNRFT 4023
             T L+  E  KF       ++   GD           P ++V WF N    P   K R T
Sbjct: 2079 TTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMT 2138

Query: 4024 PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD--ETKAVIK 4064
             I     + MN   +  EDSG+++C A N  G     TK ++K
Sbjct: 2139 FIDSVAVIQMNN--LSTEDSGDFICEAQNPAGSTSCSTKVIVK 2179



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 5/112 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            + V + P+F + L   + V+ G +  LEC++   G   +RV WF N   +    ++R  +
Sbjct: 2082 LLVTEPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTF 2139

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
                  + + ++  EDSG + C+A N  G   TSC+ +VI K+  +  S  P
Sbjct: 2140 IDSVAVIQMNNLSTEDSGDFICEAQNPAGS--TSCSTKVIVKEPPVFSSFPP 2189



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 29/99 (29%), Positives = 55/99 (55%), Gaps = 3/99 (3%)

Query: 1974 VVEKPQFGKPIKNAEVT-EGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P+F K ++ ++V  +G  + LE  ++    P ++V W+ N   + +  ++  ++  
Sbjct: 3025 VKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFIN 3082

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
                L I  A AED+G Y+C+A N VG+A  ++++ V A
Sbjct: 3083 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 3121



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 2/99 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP FI PL+ V A+ G     + +++  G P ++I W K    + ++  +   F+  
Sbjct: 3681 VLEPPYFIEPLEHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNN 3738

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
              SL +  ++  D GEY+C+A ++ G   + AVL +  R
Sbjct: 3739 VASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR 3777



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 2/102 (1%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F  ++K         V  EC+V     P + + W+  G  + SG +Y+T      
Sbjct: 4344 TVPPSFTRKLKETNGLSGSSVVMECKVYGS--PPISVSWFHEGNEISSGRKYQTTLTDNT 4401

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
             +L +  +   DSG+Y C A N  G D   A ++ ++ P  +
Sbjct: 4402 CALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV 4443



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F K  K  EV + + V L A +     P   + W+ +   ++ G ++KT     
Sbjct: 1054 VKESPYFTKEFKPIEVLKEYDVMLLAEVA--GTPPFEITWFKDNTILRSGRKYKTFIQDH 1111

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067
             V+L IL   A D G Y C+ TN VG ++ ++ V
Sbjct: 1112 LVSLQILKFVAADAGEYQCRVTNEVGSSICSARV 1145



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 23/79 (29%), Positives = 42/79 (53%)

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
            P   + W+ +  +L+SG +Y+T       +L IL     D+GEY C+  N +G ++ S R
Sbjct: 1085 PPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSAR 1144

Query: 1934 LNVQSKESIIRDSQHESAL 1952
            + ++   S I+  +  S+L
Sbjct: 1145 VTLREPPSFIKKIESTSSL 1163



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 2/125 (1%)

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            SG+ I E +    S +   + IV  PP F +        ++  V  EC  E    P   +
Sbjct: 2156 SGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLEC--ELSGTPPFEV 2213

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             WY++ + L S  +Y+        S+ IL V   D GEY C+A N+ G D    T+  K+
Sbjct: 2214 VWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE 2273

Query: 3924 LPDII 3928
             P  +
Sbjct: 2274 PPRFV 2278



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P+F      +E LK  D  H EC ++    P   + W+ + +++R+G +Y+   +    +
Sbjct: 4064 PIFRKKPHPIETLKGAD-VHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFLTS 4120

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
            + IL   A D G Y CKATN +G   +TC   +A
Sbjct: 4121 IHILNVDAADIGEYQCKATNDVGS--DTCVGSIA 4152



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P +  +G   H EC ++  P     V WY + + L+SG +Y+  ++    ++ IL V   
Sbjct: 4072 PIETLKGADVHLECELQGTPP--FHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAA 4129

Query: 1913 DSGEYTCKAINNLGQ--AVSSIRL 1934
            D GEY CKA N++G    V SI L
Sbjct: 4130 DIGEYQCKATNDVGSDTCVGSIAL 4153



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  ++++   L  G S   E ++     P + V WF+ G ++  G +Y+T       
Sbjct: 4346 PPSFTRKLKETNGL-SGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTC 4402

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             L +    E +SG+Y C+ATN  G D   A L
Sbjct: 4403 ALTVNMLEESDSGDYTCIATNMAGSDECSAPL 4434



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 4/118 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F   L  ++ V G +   EC +   G Q ++V W  + + I++G +++ +Y  +   L
Sbjct: 4818 PFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHL 4875

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
             +L V   DSG YTC A N++G+   SC  ++  K+ LI  S      E ++  E  S
Sbjct: 4876 TVLKVDKGDSGQYTCYAVNEVGK--DSCTAQLNIKERLIPPSFTKRLSETVEETEGNS 4931



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   L  VT  EG  +     ++  G   ++I+WLK G+ I+ S R +  F  G   
Sbjct: 5010 PPVFDQHLTPVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFASGTAV 5067

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            L++  +   DSG+Y C+A +  G   TK+ + +  +  +
Sbjct: 5068 LELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV 5106



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 52/233 (22%), Positives = 91/233 (39%), Gaps = 25/233 (10%)

Query: 1170 EEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            +E+    P  + PL +    SEG+    +CR+       ++V W+   + +     F+  
Sbjct: 3    QEMPVYPPAIITPLQDTV-TSEGQPARFQCRVS---GTDLKVSWYSKDKKIKPSRFFRMT 58

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
                   L+I  A   D G YT  A N +G   ++A +  +E  + +   + EQ IE   
Sbjct: 59   QFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLS-LEAPESILHERIEQEIE--- 114

Query: 1290 LLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN 1349
                           + +  AP   R +  +E   G      C +Q   +  +R +WF  
Sbjct: 115  ---------------MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPN--VRFQWFKA 157

Query: 1350 GKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            G+ I    +          +L++L     D G YTC+A+N+ G    +  L V
Sbjct: 158  GREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 56/239 (23%), Positives = 96/239 (40%), Gaps = 37/239 (15%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP  IT ++     E +  RF+CRV   +   L++ WY   K +     +R         
Sbjct: 9    PPAIITPLQDTVTSEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFRMTQFEDTYQ 65

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L+I   Y ED G Y   A N  G+  + A +S  + P+ IL  ++           + E 
Sbjct: 66   LEIAEAYPEDEGTYTFVANNAVGQVSSTANLSL-EAPESILHERI-----------EQEI 113

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
             ++   + V   + +  +V      +F  +IQS                AP    N++ +
Sbjct: 114  EMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQS----------------AP----NVRFQ 153

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYV-AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
            WF  G+ +   ++ + I    Y+ ++        D GEY C+A+N YG     A +  T
Sbjct: 154  WFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 211



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 2/99 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP FI  ++S +++ GG   F+  ++  G   + + WLK+   I         F     S
Sbjct: 1150 PPSFIKKIESTSSLRGGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTFENNVAS 1207

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            L +  + ++  G+Y C+A +  G+    A+L V   ATI
Sbjct: 1208 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATI 1246



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 56/264 (21%), Positives = 95/264 (35%), Gaps = 9/264 (3%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P   V W +    +V    +SM +       S  I+ +   D G+YT    N +G + 
Sbjct: 1831 GTPELKVKWLKDGKQIVPSRYFSMSFENNVA--SFRIQSVMKQDSGQYTFKVENDFGSSS 1888

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
            C  Y++                   V  +  H      G     S       + +G + S
Sbjct: 1889 CDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSG-----SLPISAQWFKDGKEIS 1943

Query: 217  STDDFKVDTFEYRLLREVSFRE-SITKRYVGE-SDVQISTEIDRSLGPVSPPKIAQKPRN 274
            ++  +++   E  +  EV+  E   T  Y  + S+V         L    PP    KP  
Sbjct: 1944 TSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGR 2003

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
             +    +  +F+  L G P  ++ WFK+   L++  K  I    + + L + +   S +G
Sbjct: 2004 QQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTG 2063

Query: 335  HYTLLAENPNGCIVTSGYLAVESP 358
             YT    N  G    +  L V  P
Sbjct: 2064 QYTCHVTNDVGSDSCTTMLLVTEP 2087



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 27/112 (24%), Positives = 57/112 (50%), Gaps = 3/112 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP+FV +L  +    +G++   EC++     P +++ ++ N   L  + +++++F     
Sbjct: 3028 PPKFVKKLEASKVAKQGESIQLECKISG--SPEIKVSWFRNDSELHESWKYNMSFINSVA 3085

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEK 2352
             L I     ED+G+Y  +A N +G  + + ++TV A   + ++   P G  K
Sbjct: 3086 LLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAP-PVFTQKPSPVGALK 3136



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   LK  + ++ G  V LE +V       + + WF++G  + +G + +S+F   + T
Sbjct: 3406 PSFIRKLKDVNAIL-GASVVLECRVSGSAP--ISVGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L+++ L   D+GIYTC A N+ G    +A + +++
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE 3497



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 43/157 (27%), Positives = 65/157 (41%), Gaps = 8/157 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG   + + W  +   I  S R          +LEIL +   D   YSC   N+ GQ +I
Sbjct: 3616 TGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQ-DI 3674

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L  V     + P F   ++++E +  G+ A  +C V     P+++I WY     +R 
Sbjct: 3675 CEALVSVL----EPPYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRS 3727

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +   K         L I    + D GEY C+A N  G
Sbjct: 3728 APAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVG 3764



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 2/95 (2%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  L    +  EG    LE +V   + P + + W+KN + +   +  + TF    + 
Sbjct: 4914 PSFTKRLSETVEETEGNSFKLEGRVAG-SQP-ITVAWYKNNIEIQPTSNCEITFKNNTLV 4971

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L +     +D+G+YTCK +N  G A+ T+SI I++
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE 5006



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 53/198 (26%), Positives = 84/198 (42%), Gaps = 17/198 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            +PP F      +  +SEG+  + + S    G + + I+W   G+ I+ S R    +A G 
Sbjct: 5009 KPPVFDQHLTPVT-VSEGE--YVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGT 5065

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK---SKGQKPR-------FTTHI 3155
             VLE+      DSG Y C+A+N  G      K+   DK   +   K         F +  
Sbjct: 5066 AVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEP 5125

Query: 3156 QNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYT 3214
            Q+I  + +  +A F   V    DP   ++W     + +    R+          L+I  T
Sbjct: 5126 QSIR-VVEKTTATFIAKV--GGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDT 5182

Query: 3215 QNHDSGEYVCRAYNKYGE 3232
               DSG Y C A+N++GE
Sbjct: 5183 TKTDSGLYRCVAFNEHGE 5200



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 2/101 (1%)

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
            Q +  +++KP F K ++  +      VHLE  +    D  + V W  +G+ +  G  +K 
Sbjct: 300  QAELIIIDKPHFIKELEPVQSAINKKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYKI 357

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             ++     L+I  A  +D+GTY+C A+N  G +  +++V V
Sbjct: 358  CFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 398



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 25/99 (25%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++ ++  P F + L  +++     VHLEC++    D+ + V W  +G+ +  G  ++  +
Sbjct: 302  ELIIIDKPHFIKELEPVQSAINKKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICF 359

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            E     L++     +DSG Y C A+N+ G +  S  + V
Sbjct: 360  EDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 398



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 3/94 (3%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            +P F+  L  +++     + H EC+V+   D  +T+ W  +GQK+  G  Y+   +    
Sbjct: 308  KPHFIKELEPVQSAIN-KKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYKICFEDKIA 364

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L+I     +DSGTY+C A+N+ G +  + T+ V
Sbjct: 365  TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 398



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 4/103 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR-TFCDFGFV 3478
            P F    S +  LR G++  FE ++T T  P ++V WY +G  + A  +   +F D G  
Sbjct: 1526 PQFIKKPSPVLVLRNGQSTTFECQITGT--PKIRVSWYLDGNEITAIQKHGISFID-GLA 1582

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
              +IS    E+SG Y+C A N+ G A  +  +KV+     I E
Sbjct: 1583 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE 1625



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 26/95 (27%), Positives = 52/95 (54%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  L   DK++ G  +++E +V       +  +WFK+G  ++T A+ +       V+
Sbjct: 1902 PSFTKKLTKMDKVL-GSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L +N+L  +D+  YTCK +N+ G+   +  + +++
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE 1993



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L + +  K+G+    EC++     P + + WF N  ++    +Y  +       
Sbjct: 3029 PKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSVAL 3086

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L I    AEDSG Y+C+A N +G+A  +  L V
Sbjct: 3087 LTINEASAEDSGDYICEAHNGVGDASCSTALTV 3119



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            + P F+ + K + N I G  V  EC++     + + V WF++G  +  G + +       
Sbjct: 3404 VPPSFIRKLKDV-NAILGASVVLECRVSG--SAPISVGWFQDGNEIVSGPKCQSSFSENV 3460

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L++  L   D+GIYTC A N+ G+DE S  LT
Sbjct: 3461 CTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLT 3494



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 3/100 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F + L     +S G ++ +EC++   G P + V WFH G  ++ G +++T       A
Sbjct: 4347 PSFTRKLKETNGLS-GSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 4403

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276
            L +     +D+G+YT  A N  GS   SA + V E    V
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV 4443



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/103 (32%), Positives = 50/103 (48%), Gaps = 2/103 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F+ + +S  V  +  V+ +  V       + I+W+++ K L SG       D  
Sbjct: 1429 VKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAP--MTIKWFKDNKELHSGAARSVWKDDT 1486

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
              SL++    A DSG YIC+  ND G   +KAT+  K+ P  I
Sbjct: 1487 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFI 1529



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 4/93 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L + + +K GD +  EC++     P + + WF N  ++ A  +YR T       
Sbjct: 2088 PKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDSVAV 2145

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            + +     EDSG ++C+A N  G    +C+ KV
Sbjct: 2146 IQMNNLSTEDSGDFICEAQNPAGS--TSCSTKV 2176



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P  +   + P  V+ G+   LEC++   G P + VEW+ +G+ +T   + K  +     
Sbjct: 2367 EPAVIVEKAGPMTVTVGETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKIS 2424

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273
            +L I+     D G YT +  N++G +  +A+V V +R+
Sbjct: 2425 SLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA 2462



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 25/67 (37%), Positives = 41/67 (61%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P + VEWYKDG+ +T+S +    F     SL I+ +  +DAG+YT +  N +G++  TA 
Sbjct: 2396 PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAV 2455

Query: 860  IRVAARS 866
            + V+ R+
Sbjct: 2456 VDVSDRA 2462



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 25/94 (26%), Positives = 54/94 (57%), Gaps = 2/94 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PPRF+ +L  +  V + +   +EC++     P +++ +Y +   +Q +++F ++F     
Sbjct: 3969 PPRFIKKLEPSRIVKQDEFTRYECKIGG--SPEIKVLWYKDETEIQESSKFRMSFVDSVA 4026

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             L++ +   ED+G+Y+ +A NA G  +S+ S+ V
Sbjct: 4027 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 4060



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 2/90 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P FSR L +++   G  V  +C +   G + + V W+ +GKP+K     + ++  +   L
Sbjct: 4722 PSFSRQLRDVQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNVQTSFLDNTATL 4779

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
            ++       +G Y+C ATN +G A +S  L
Sbjct: 4780 NIFKTDRSLAGQYSCTATNPIGSASSSARL 4809



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 4/106 (3%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            I I++ K  PP F   +   + V EG  V   C V+  G   +RI W   GR      R 
Sbjct: 5002 IVIKEPK-KPPVFDQHLTP-VTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRC 5057

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
                  G   L++  +   D+G+Y C+A+N  GS TT +K+T   K
Sbjct: 5058 SFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDK 5103



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 2/77 (2%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            + K GD+   EC +  S  P +++ WF N   LP+  +Y+ T   S   + + +   EDS
Sbjct: 2099 IVKAGDSSRLECKIAGS--PEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDS 2156

Query: 2844 GIYTCKATNSKGSATTS 2860
            G + C+A N  GS + S
Sbjct: 2157 GDFICEAQNPAGSTSCS 2173



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  LK+   ++ G    LE +V   +   + + WF     + +GA+ ++TF   + T
Sbjct: 2465 PSFTRRLKNTGGVL-GASCILECKVAGSSP--ISVAWFHEKTKIVSGAKYQTTFSDNVCT 2521

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L +NSL + D G YTC A N+ G     A + +++
Sbjct: 2522 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE 2556



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            ++P F     +I+ + G +   EC +   G Q MR+ W  + K I+ G  +      +  
Sbjct: 2934 KSPFFDIKPVSIDVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTITCVGNTP 2991

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             L +L V   DSG YTCQATN +G+ + S  L V
Sbjct: 2992 HLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 3025



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 39/144 (27%), Positives = 68/144 (47%), Gaps = 5/144 (3%)

Query: 3371 NLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIE 3430
            N K T  EN    + L  G +G   +      ++  +   S +    + P F   L    
Sbjct: 3922 NYKMTLVENTATLTVLKVG-KGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSR 3980

Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR-TFCDFGFVILEISPTYPED 3489
             +++ E   +E ++  +  P +KV WY +   ++  S+FR +F D    +LE+     ED
Sbjct: 3981 IVKQDEFTRYECKIGGS--PEIKVLWYKDETEIQESSKFRMSFVD-SVAVLEMHNLSVED 4037

Query: 3490 SGEYLCRAYNNYGEAVTTASMKVQ 3513
            SG+Y C A+N  G A ++ S+KV+
Sbjct: 4038 SGDYTCEAHNAAGSASSSTSLKVK 4061



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 2/100 (2%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            ++PPRF+ +++    + + E T++EC++   G P +KV W+ +   +   ++F   +   
Sbjct: 3967 QEPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDS 4024

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
               +    +  EDSG+Y C A N  G   +   +K    P
Sbjct: 4025 VAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 4064



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 3/83 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   L     L  G     EC+V     P +++ WFH G +I +G +Y+TT      A
Sbjct: 4347 PSFTRKLKETNGLS-GSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 4403

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L +      DSG Y C ATN  G
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAG 4426



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 4/100 (4%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            V  ++PP FV ++     ++  E+ +  C+L   G P ++V WF N K L   N     +
Sbjct: 396  VTVREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYF 453

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMD--ETKAVIK 4064
                  ++   V  EDSG Y C A N  G D   T+ VIK
Sbjct: 454  VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK 493



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 8/122 (6%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+P  FV +++    L + + T+  C++   G P +K+ WF N + +   ++    +   
Sbjct: 961  KEPATFVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFVES 1018

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE 4089
               +    V  EDSGEY+C A N  G D   +++     P         K  K IE ++E
Sbjct: 1019 TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP------YFTKEFKPIEVLKE 1072

Query: 4090 ME 4091
             +
Sbjct: 1073 YD 1074



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 3/114 (2%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I K  P F +      P+   K   +    E  G P   + WF +   +  G ++KT+  
Sbjct: 1053 IVKESPYFTKEFK---PIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQ 1109

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAI 1285
               V+L I+   +AD GEY  R  N +GS+  SA V + E    +   ++  ++
Sbjct: 1110 DHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSL 1163



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 49/179 (27%), Positives = 76/179 (42%), Gaps = 16/179 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            + P F      +E LKE D        E    P   I WF +   +R+G +Y+T      
Sbjct: 1056 ESPYFTKEFKPIEVLKEYD---VMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHL 1112

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226
            V+L IL   A D+G Y C+ TN++G ++  C+ +V          + P+ ++KI    + 
Sbjct: 1113 VSLQILKFVAADAGEYQCRVTNEVGSSI--CSARVTLR-------EPPSFIKKIESTSSL 1163

Query: 2227 GHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAH--FECQVEPVHDPNLRIEFYHNGK 2283
               T       K S P  VT L+ +  + E       FE  V  ++     IE  H+GK
Sbjct: 1164 RGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSG--IEVKHDGK 1220



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 33/163 (20%), Positives = 64/163 (39%), Gaps = 7/163 (4%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E   I  G     I+WF +   + +  +           L +     + +G Y+C  TN 
Sbjct: 2013 EFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTND 2072

Query: 3129 WGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHN 3188
             G    +  L        + P+F   ++  + +K G S+  EC +     P++++ W+ N
Sbjct: 2073 VGSDSCTTMLLVT-----EPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRN 2125

Query: 3189 GQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               +  S + +        V+ +      DSG+++C A N  G
Sbjct: 2126 EHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAG 2168



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 2/98 (2%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V + P+F+ +L     +  G S+  EC+I   P+  +RV W+ N   L +  +YR +   
Sbjct: 2084 VTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPE--IRVVWFRNEHELPASDKYRMTFID 2141

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
              A + +  +  EDSG++ C+A N  G    S ++ V+
Sbjct: 2142 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 2179



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 3/109 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F+   + +  + G  + F + I   G P  K+ W +  + +    R    F   
Sbjct: 2554 VQEPPSFVKEPEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDT 2611

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQH 740
               L++ +++I  SGEYTC   +  G A     L V  P A ++R S H
Sbjct: 2612 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDH 2660



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/101 (28%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 1305 ITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++V + P+F + L   +   +G ++ LEC++   G   ++V WF N   +    ++  ++
Sbjct: 3023 LSVKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSF 3080

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
                  L +     EDSG Y C+A N +G+A  S AL V A
Sbjct: 3081 INSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 3121



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F   L++     +G+ + LE ++     P +K+ WF+N   L    +   +F  
Sbjct: 3025 VKEPPKFVKKLEASKVAKQGESIQLECKISG--SPEIKVSWFRNDSELHESWKYNMSFIN 3082

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             +  L+IN    +DSG Y C+A N +G+A  + ++ ++
Sbjct: 3083 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVK 3120



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P FV+ L       +G++I LEC++   G P ++V WF N   +    ++   +   
Sbjct: 3026 KEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINS 3083

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
               L I  A++ D+G+Y   A N +G A  S  + V
Sbjct: 3084 VALLTINEASAEDSGDYICEAHNGVGDASCSTALTV 3119



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F + L+     ++G++   +C++   G P +KV WFRN+  + +S +   +    
Sbjct: 3026 KEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINS 3083

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459
               +TI+    ED G Y+C A N +G+
Sbjct: 3084 VALLTINEASAEDSGDYICEAHNGVGD 3110



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I+  +G  VH +C ++  G P   + W+ + R   +G +   +++    ++ I  + A D
Sbjct: 4073 IETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAAD 4130

Query: 3765 AGEYTCRATNKWGSATTTAKITCSA 3789
             GEY C+ATN  GS T    I   A
Sbjct: 4131 IGEYQCKATNDVGSDTCVGSIALKA 4155



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            T  P F   LK TN +  G S   E +V     ++  V W+  G +I+S  + QT     
Sbjct: 4344 TVPPSFTRKLKETNGL-SGSSVVMECKVYGSPPIS--VSWFHEGNEISSGRKYQTTLTDN 4400

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              AL +  +   DSG YT +A N AG  + SA +TV
Sbjct: 4401 TCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 4436



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 87/386 (22%), Positives = 149/386 (38%), Gaps = 38/386 (9%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   P  + +   ++  F    I        V WF     L+ G R     +     
Sbjct: 4439 PPSFVQKPDPMDVLTGTNVTFTS--IVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAE 4496

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            LE+  V    +G YTC  +N  G+A+ +  L +K     +      S  + G   I  LE
Sbjct: 4497 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYS-IEKGKPLI--LE 4553

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHF--DCRVEPVGDPTMRIDWFHN 3734
             T      I++  +K N    T   + NI   E  P+       VE  G     I+   +
Sbjct: 4554 GTFTGTPPISVTWKK-NGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIE-NAS 4611

Query: 3735 GRPFATGSRVHTLNDFGFIA-LDIDYIYARDAGEYTCRATN------KWGSATTTAKITC 3787
            G+  +  +++  L    F+  L+   +   D+    C+          W    T  + T 
Sbjct: 4612 GKD-SCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTT 4670

Query: 3788 SAKRDI------VLESQLPQGMSGEKIKELER--GRISDAP----KEEPIVSTPPKFITQ 3835
            + K         ++ +Q+    SGE I + E   G +S +     +E+ +   PP F  Q
Sbjct: 4671 TYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKL---PPSFSRQ 4727

Query: 3836 IKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILY 3893
            ++   V+E+ G  V F+C +   E   + + WY++GK L      +T +     +L+I  
Sbjct: 4728 LRD--VQETVGLPVVFDCAISGSEP--ISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFK 4783

Query: 3894 VYAEDSGEYICRAVNDFGEDFTKATI 3919
                 +G+Y C A N  G   + A +
Sbjct: 4784 TDRSLAGQYSCTATNPIGSASSSARL 4809



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 45/153 (29%), Positives = 74/153 (48%), Gaps = 13/153 (8%)

Query: 388  KALAPQFVKVCQDRDVTE----GKMTRFDCRVTGRPYPEVT-WFINDRQIRDDYNHKILV 442
            KA+  +FVK  +D  +TE    G    F+C V+  P   +T W  +   IR+   H+ + 
Sbjct: 7798 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIA 7855

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
             +  +  L I +V LSD+G  TCV R  + E     +L V+E+  V   K +E    + V
Sbjct: 7856 -DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKL-VVEELPVRFVKTLE--EEVTV 7911

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNP 535
             +G+P+ L+          + W+KDG  ++  P
Sbjct: 7912 VKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 7942



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 27/96 (28%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP FT  L++ D +V G    L+ ++       +++ WFK+G  +    R +  F  G  
Sbjct: 777  APFFTKPLRNVDSVVNGT-CRLDCKIAGSLP--MRVSWFKDGKEIAASDRYRIAFVEGTA 833

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            +L I  +  +D+G +TC+ATN +G   S+ ++ +++
Sbjct: 834  SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE 869



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V+++P FT   K  + L E   V L A+V     P  +I WFK+   L +G + K+    
Sbjct: 1054 VKESPYFTKEFKPIEVLKE-YDVMLLAEVAGT--PPFEITWFKDNTILRSGRKYKTFIQD 1110

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             LV+L I      D+G Y C+ TN +G ++ +A + + +
Sbjct: 1111 HLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLRE 1149



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)

Query: 630  EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            E +V  PP FI  LK V  ++   +  E  +   G P  ++ WLKN + I +S ++T   
Sbjct: 1613 ELKVKEPPTFIRELKPVEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTD 1670

Query: 690  RFGYISLDMLSLNIQDSGEYTC 711
            R    +L +   +  D+GEY C
Sbjct: 1671 RVSVFNLHITKCDPSDTGEYQC 1692



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 2/118 (1%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S + D      +   PP FT   + +     SS H EC++       +  +WF +GK + 
Sbjct: 1886 SSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEIS 1943

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            T ++ + +     V LE+  +   D   YTCK +N  G+   S  L VK     +++P
Sbjct: 1944 TSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKP 2001



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   L  +  + G  IH E ++   G   +  +W K+G+ I  S+++  +     +S
Sbjct: 1901 PPSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L++ +L ++D+  YTC+  +  G      +L V
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAGDDACSGILTV 1991



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPPKF+ +++      +G+S   E ++     P++KV WF N  +L    +Y       +
Sbjct: 3027 EPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSV 3084

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +L I     E+SG+Y C A N +G  S    L
Sbjct: 3085 ALLTINEASAEDSGDYICEAHNGVGDASCSTAL 3117



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 2/95 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F  ++        E   FEC V   +   +++ W ++ + + SG +Y+  Y      
Sbjct: 4817 PPFFDIRLAPVDAVVGESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLENSAH 4874

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
            L +L V   DSG+Y C AVN+ G+D   A ++ K+
Sbjct: 4875 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE 4909



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 51/212 (24%), Positives = 83/212 (39%), Gaps = 24/212 (11%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EGQ    + +V   TD  LK+ W+     +      + T       L I     +D G Y
Sbjct: 23   EGQPARFQCRVSG-TD--LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 79

Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXV 2775
            T  A N +G+  STA++ +E    +L E +  +       +                  V
Sbjct: 80   TFVANNAVGQVSSTANLSLEAPESILHERIEQE-------IEMEMKAAPVIKRKIEPLEV 132

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SLD 2834
             + HL            F C ++ +  P ++ +WF   + +    +  S     Y+ SL+
Sbjct: 133  ALGHL----------AKFTCEIQSA--PNVRFQWFKAGREIYESDKC-SIRSSKYISSLE 179

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
            I  T   D G YTCKA+N  GS + + +L  T
Sbjct: 180  ILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 211



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 3/108 (2%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            E+ +   P FI +L  P + +  +  H EC+++   D  + V W  +G+ L  G  Y+  
Sbjct: 302  ELIIIDKPHFIKELE-PVQSAINKKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKIC 358

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
             +   A L+I     +DSG Y C A N  G +  S  + V+   S ++
Sbjct: 359  FEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVK 406



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L  +       +H EC V+  R  T  + W  + + LP G  YK   +    +L+I
Sbjct: 311  FIKELEPVQSAINKKVHLECQVDEDRKVT--VTWSKDGQKLPPGKDYKICFEDKIATLEI 368

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +DSG Y C A+N  GS++ S ++
Sbjct: 369  PLAKLKDSGTYVCTASNEAGSSSCSATV 396



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 7/169 (4%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP FT PL N++++  G     + ++  +    ++V W+ +GK + A  R+R     G  
Sbjct: 777  APFFTKPLRNVDSVVNG-TCRLDCKIAGSLP--MRVSWFKDGKEIAASDRYRIAFVEGTA 833

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
             LEI      D+G + CRA N+ G   ++ ++ VQ   + + +      + G+   +   
Sbjct: 834  SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGS--AVCLK 891

Query: 3539 EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
              + G+   LT     GN  E  +  S  I  E   +  E  L+  +DS
Sbjct: 892  STFQGST-PLTIRWFKGN-KELVSGGSCYITKEALESSLELYLVKTSDS 938



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  LK  D  ++G  + LE  V   + P + I+WFK+   ++   + K +F      
Sbjct: 1340 PSFTKKLKKMDS-IKGSFIDLECIVAG-SHP-ISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L I+ L   DSG YTC ATN  G    +  + +++
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE 1431



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 12/143 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+F+ +P  +  +  GQ   FEC++       ++V W+ +G  +T   +       G   
Sbjct: 1526 PQFIKKPSPVLVLRNGQSTTFECQITGTP--KIRVSWYLDGNEITAIQKHGISFIDGLAT 1583

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
              I     E+SG Y C A N  GT   S  L  +     +R       L+ ++V+    K
Sbjct: 1584 FQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE------LKPVEVV----K 1633

Query: 1564 YHRTDMVDEVTTQAPICTTSLKN 1586
            Y   ++  EVT   P   T LKN
Sbjct: 1634 YSDVELECEVTGTPPFEVTWLKN 1656



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 43/188 (22%), Positives = 72/188 (38%), Gaps = 8/188 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  PP F T  + + + + G     +  +   G   + + W+     +  +   RT +  
Sbjct: 2740 TLEPPYFVTELEPL-EAAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTN 2796

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
             +  L        DSG Y+C+A N  G A  S K     + +   P F   +++IE    
Sbjct: 2797 NVATLVFNKVNINDSGEYTCKAENSIGTA--SSKTVFRIQERQLPPSFARQLKDIEQTV- 2853

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G      C +       +++ WY +G  +R    ++T        L I  T    SG+Y 
Sbjct: 2854 GLPVTLTCRL--NGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYS 2911

Query: 3224 CRAYNKYG 3231
            C A N  G
Sbjct: 2912 CSASNPLG 2919



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 13/143 (9%)

Query: 1937 QSKESIIRDSQHESALEKIQY-LEDDSRYKRAVQDDS---------FVVEKPQFGKPIKN 1986
            QS+   I  ++  + LE ++  +ED ++Y   +++++          V+E P F +P+++
Sbjct: 3634 QSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEH 3693

Query: 1987 AEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAED 2046
             E   G P  L+  +     P +R+ WY     ++    +K  +     +L I      D
Sbjct: 3694 VEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSD 3751

Query: 2047 TGTYMCKATNAVGEAVTTSSVKV 2069
             G Y CKA N+VG AV +S+V V
Sbjct: 3752 VGEYSCKADNSVG-AVASSAVLV 3773



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D+  PP F  +++ +T+ +   +   EC++   G P + V WF  G  +    ++     
Sbjct: 4342 DRTVPPSFTRKLK-ETNGLSGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLT 4398

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                A+    +   DSG+Y C ATN+ G DE  A +     P  V
Sbjct: 4399 DNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV 4443



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G ++  EC V  S  P + + WF     + SG +Y++T   +  +L +    E DSG YT
Sbjct: 4361 GSSVVMECKVYGS--PPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYT 4418

Query: 2848 CKATNSKGSATTSGSL 2863
            C ATN  GS   S  L
Sbjct: 4419 CIATNMAGSDECSAPL 4434



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 3/102 (2%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            KP F+   + +++ I  + VH EC+++   D  + V W K+GQ +  G  ++   +    
Sbjct: 308  KPHFIKELEPVQSAIN-KKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIA 364

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVR 1544
             L+I     +DSG Y C A N  G+   S  +T R     V+
Sbjct: 365  TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVK 406



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 2/80 (2%)

Query: 3851 CRVEPKEDPKL--RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
            CR++ K    L  R+ W+++GK + +  RYR  +  G  SL+I+ V   D+G + CRA N
Sbjct: 795  CRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATN 854

Query: 3909 DFGEDFTKATISCKKLPDII 3928
              G   +   +  ++ P  +
Sbjct: 855  SVGSKDSSGALIVQEPPSFV 874



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 51/224 (22%), Positives = 90/224 (40%), Gaps = 19/224 (8%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    +    +  G  A ++A+L   G   + + W  +   I     IR  +   + 
Sbjct: 1150 PPSFIKKIESTSSLRGGTAA-FQATL--KGSLPITVTWLKDSDEITEDDNIRMTFENNVA 1206

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L + G +    G Y C+A N  G    S  L     S  +    T    +I+ +  G  
Sbjct: 1207 SLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL-----SVKEPATITEEAVSID-VTQGDP 1260

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A  +  V      ++  +W+ +GQ +   ++ K        +L I  T+  DSGEY    
Sbjct: 1261 ATLQ--VKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEV 1318

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLA-KIRELESLQGA 3269
             N  G    +A IN        L+ + P S   K+++++S++G+
Sbjct: 1319 QNDVGRSSCKARIN-------VLDLIIPPSFTKKLKKMDSIKGS 1355



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 35/119 (29%), Positives = 51/119 (42%), Gaps = 2/119 (1%)

Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314
            DS   I +L +  G      +    EPP+FI +   V  L  GQS  FE ++     P +
Sbjct: 1499 DSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGT--PKI 1556

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
            +V W+ +G ++    ++      G+    I     ENSG Y C A N  G  S    LK
Sbjct: 1557 RVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELK 1615



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 4/103 (3%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++ V + P F R L  +E V+ ++V LEC +   G     V W  N + I++  ++    
Sbjct: 1613 ELKVKEPPTFIRELKPVEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTD 1670

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
                  L +    P D+G Y C  +N+ G    SC+ RV  K+
Sbjct: 1671 RVSVFNLHITKCDPSDTGEYQCIVSNEGGSC--SCSTRVALKE 1711



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 11/126 (8%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            +V  P + + + KS  V E + +  EC V     P+L+++W ++GK +     +   ++ 
Sbjct: 1801 LVQEPAQIVEKAKSVDVTEKDPMTLECVVAGT--PELKVKWLKDGKQIVPSRYFSMSFEN 1858

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
               S  I  V  +DSG+Y  +  NDFG        SC     ++ QN  P   K+   LT
Sbjct: 1859 NVASFRIQSVMKQDSGQYTFKVENDFGSS------SCDAYLRVLDQNIPPSFTKK---LT 1909

Query: 3945 QMEATI 3950
            +M+  +
Sbjct: 1910 KMDKVL 1915



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 25/98 (25%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V + P FS     +ET++   V LEC L   G     V W+ + + +++  +++ A +
Sbjct: 2176 VIVKEPPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASK 2233

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
              + ++ +L+V   D G Y C+A N++G     C +++
Sbjct: 2234 NFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL 2271



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 4/107 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRF 1359
            + R  +TV + P F +    +E + G NV     ++  G    +V WF   + +  G R 
Sbjct: 2547 ECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRC 2604

Query: 1360 RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
               +E     L+L ++    SG YTC  +N  G+A  SC  R+  K+
Sbjct: 2605 NIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQA--SCTTRLFVKE 2649



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+T L  LE    GD    +C+V     P +T+ W+    K+R    YRT        
Sbjct: 2744 PYFVTELEPLE-AAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTNNVAT 2800

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L        DSG Y CKA N +G A +    ++
Sbjct: 2801 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRI 2833



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 4/125 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L   +  ++GE+   E +++ +  P +KV W+ N   L    ++         +
Sbjct: 3029 PKFVKKLEASKVAKQGESIQLECKISGS--PEIKVSWFRNDSELHESWKYNMSFINSVAL 3086

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            L I+    EDSG+Y+C A+N  G+A  + ++ V+    +  +   P G     D I   E
Sbjct: 3087 LTINEASAEDSGDYICEAHNGVGDASCSTALTVKAP-PVFTQKPSPVGALKGSDVILQCE 3145

Query: 3540 GYSGT 3544
              SGT
Sbjct: 3146 -ISGT 3149



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 3/103 (2%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V+V + P FI  L     +  G+ A  +C+++  P+  +R+ WY     L+S   Y+   
Sbjct: 3679 VSVLEPPYFIEPLEHVEAVI-GEPATLQCKVDGTPE--IRISWYKEHTKLRSAPAYKMQF 3735

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
                A+L I  V   D GEY+CKA N++G   SS  L +++++
Sbjct: 3736 KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK 3778



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 4/117 (3%)

Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK 3870
            +E     D+   + ++  PP F+ Q++   V   +    +C++     P++ + WY+   
Sbjct: 4607 IENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGT--PEIGVSWYKGDT 4664

Query: 3871 LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE--DFTKATISCKKLP 3925
             L     Y+  +     +L    V   DSGEYIC+A N  GE    T  T+  +KLP
Sbjct: 4665 KLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLP 4721



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 42/179 (23%), Positives = 78/179 (43%), Gaps = 21/179 (11%)

Query: 1690 QLEDTSKYQR----HSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
            QL+D   Y+     H A  ++    P +   ++D+ + E Q        +    P ++ E
Sbjct: 5385 QLKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVTLKEGQTC---TMTVQFSVPNVKSE 5441

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W RNG  ++   R  T  +     L +  V  ED G YTC+  +            +++ 
Sbjct: 5442 WFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYED------------LETS 5489

Query: 1806 ASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHY 1864
            A L++E++     ++IQ +  S       + EV+ + A   +T   GPT+L+E Q  ++
Sbjct: 5490 AELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDA--IVTWYKGPTELTESQKYNF 5546



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 18/154 (11%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P + + LQ++  ++EGQT       +    P +K EWFRN ++++   R     +     
Sbjct: 5410 PAWERHLQDV-TLKEGQTCTMT---VQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHK 5465

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKL-EQPH 2494
            +TI+ VR ED+G Y C+  +L                 +++E +  +  K+IQ +    H
Sbjct: 5466 LTIADVRAEDQGQYTCKYEDL------------ETSAELRIEAEPIQFTKRIQNIVVSEH 5513

Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528
            +  + E +  F+  I T    GP+EL E Q  ++
Sbjct: 5514 QSATFECEVSFDDAIVTW-YKGPTELTESQKYNF 5546



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 53/241 (21%), Positives = 89/241 (36%), Gaps = 30/241 (12%)

Query: 2501 PDREFEKPIFTQVLTGPSE---LWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRF 2557
            PD+E   P++   +  P +     EGQ A ++ RV       L+  WY    ++K    F
Sbjct: 1    PDQEM--PVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFF 55

Query: 2558 RTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWE 2617
            R T       L+I      D G Y   A N  G               I+ + +  E   
Sbjct: 56   RMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEM 115

Query: 2618 QIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIE 2677
            +++       K+  + V  G         HL  +               E ++ PN++ +
Sbjct: 116  EMKAAPVIKRKIEPLEVALG---------HLAKFT-------------CEIQSAPNVRFQ 153

Query: 2678 WFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            WFK G  +    +        + +L I   +  D G YTCKA+N  G    TA++ + + 
Sbjct: 154  WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA 213

Query: 2738 H 2738
            +
Sbjct: 214  Y 214



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            SD+   E ++  PP FI  ++   +        +C V         I W+++ K + S  
Sbjct: 483  SDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSK 540

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +YR       V L+I    + D GEY C   N+ G+    AT   K+ P  +
Sbjct: 541  KYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFV 592



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 3/101 (2%)

Query: 3826 VSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  P  F+ +++ S  +++ +  +  C+V     P ++I W+ N + +    ++R  +  
Sbjct: 960  VKEPATFVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVE 1017

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L +  V  EDSGEY+C A N+ G D   + +  K+ P
Sbjct: 1018 STAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 1058



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 5/112 (4%)

Query: 3542 SGTVDTLTPEAES--GNPPEFTTTPSD-LILSENSSAHFECRLIPVNDSSMRVEWFHNGK 3598
            S  V T T +A      PP+F   PS  L+L    S  FEC++       +RV W+ +G 
Sbjct: 1508 SNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGN 1565

Query: 3599 PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             +    +       G    +I G    ++G Y C+A N  G A+ S +L+VK
Sbjct: 1566 EITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 1617



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 12/171 (7%)

Query: 1973 FVVEKPQF-GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031
            FV E PQF  KP     +  G     E  +T    P +RV WY +G  +    +   ++ 
Sbjct: 1521 FVKEPPQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFI 1578

Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQEL 2091
             G     I  A  E++GTY+C+A N  G A  +  +KV  +   ++  L    + K  ++
Sbjct: 1579 DGLATFQISGARVENSGTYVCEARNDAGTASCSIELKV-KEPPTFIRELKPVEVVKYSDV 1637

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLT 2142
            E       +E E  G  P  +T L +   ++   +     RV   N  H+T
Sbjct: 1638 E-------LECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN-LHIT 1680



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 39/170 (22%), Positives = 74/170 (43%), Gaps = 9/170 (5%)

Query: 411  FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM-ITNVTLSDSGVVTCVARN 469
            F   + G P  ++ WF +D ++      K  +   G+ + + + +V  S +G  TC   N
Sbjct: 2014 FKAILKGTPPFKIKWFKDDVELVS--GPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTN 2071

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLN-VREGEPVVLNARAVGTPTPRITWQKDG 528
              G  +    L V E      PKFV++      V+ G+   L  +  G+P  R+ W ++ 
Sbjct: 2072 DVGSDSCTTMLLVTEP-----PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNE 2126

Query: 529  VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +  + + R+      + + +      D+  + C AQN AGST+   ++
Sbjct: 2127 HELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV 2176



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 2/95 (2%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            +V  P   + +    TV   E    EC+V     P+L +EWY++GKLL S  +++  +  
Sbjct: 2364 MVLEPAVIVEKAGPMTVTVGETCTLECKVAGT--PELSVEWYKDGKLLTSSQKHKFSFYN 2421

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               SL IL V  +D+G Y  +  N+ G+    A +
Sbjct: 2422 KISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVV 2456



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FV  L  P   + G ++ L+C++   G P + V W+     +     ++TY+      
Sbjct: 2744 PYFVTELE-PLEAAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTNNVAT 2800

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            L        D+GEYT +A N +G+A +  + R+ ER
Sbjct: 2801 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 2836



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 3/100 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V + P F   L+  + ++ G+   L+ +V+    P ++I W+K    L +    K  F  
Sbjct: 3681 VLEPPYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKN 3737

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             + +L IN + + D G Y+CKA N +G   S+A + I+ R
Sbjct: 3738 NVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR 3777



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 3/99 (3%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            + PP F+  L     V  G+ A  +C+V+    P +RI +Y     L+SA  + + F   
Sbjct: 3682 LEPPYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNN 3738

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
              SL I      D GEYS KA N++G   S+  + + A+
Sbjct: 3739 VASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR 3777



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 67/249 (26%), Positives = 101/249 (40%), Gaps = 20/249 (8%)

Query: 3276 TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH 3335
            T    PP F  ++  V  +V G+SA FE  +       +KV W  + +++  G +Y+  +
Sbjct: 4812 TEGKNPPFFDIRLAPVDAVV-GESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISY 4868

Query: 3336 DFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDS---QLPRGMEG 3392
                  L +L   + +SG+Y C A N++G+DS  A L    KE LI  S   +L   +E 
Sbjct: 4869 LENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI--KERLIPPSFTKRLSETVEE 4926

Query: 3393 GLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNL 3452
                   LE  +   +  +V   K    +   P SN E   +      + R    +D  L
Sbjct: 4927 TEGNSFKLEGRVAGSQPITVAWYKNNIEI--QPTSNCEITFKNNTLVLQVRKAGMNDAGL 4984

Query: 3453 KVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
                Y    S  AGS     C    VI E  P  P    ++L     + GE V   S  V
Sbjct: 4985 ----YTCKVSNDAGS---ALCTSSIVIKE--PKKPPVFDQHLTPVTVSEGEYV-QLSCHV 5034

Query: 3513 QGKRNIILE 3521
            QG   I ++
Sbjct: 5035 QGSEPIRIQ 5043



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 2/98 (2%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +  P FV+ +     +  G++  L C+L+  G P ++V WF N + ++  +  + Y+   
Sbjct: 399  REPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNS 456

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               LDI      D+G Y+  AVN +GS   S  + + E
Sbjct: 457  EAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE 494



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F KP++N +        L+  +       MRV W+ +G+ +    R++  +  G  +L
Sbjct: 778  PFFTKPLRNVDSVVNGTCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 835

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +I+     D G + C+ATN+VG   ++ ++ V
Sbjct: 836  EIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 867



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 13/151 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+   + +  L+ G    FEC++     P + + W+ +G +I A  ++  +   G   
Sbjct: 1526 PQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 1583

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGH 2228
              I     E+SGTY+C+A N  G A  +  LKV          + P  + +++ +E   +
Sbjct: 1584 FQISGARVENSGTYVCEARNDAGTASCSIELKV---------KEPPTFIRELKPVEVVKY 1634

Query: 2229 STRIEVE-EPKISPPRFVTELRGTTHVFEGK 2258
            S  +E+E E   +PP  VT L+    +   K
Sbjct: 1635 SD-VELECEVTGTPPFEVTWLKNNREIRSSK 1664



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  P Q +   KSV   E   +  E  +   G P +K++WLK+G+ I  S  F+  F   
Sbjct: 1802 VQEPAQIVEKAKSVDVTEKDPMTLECVV--AGTPELKVKWLKDGKQIVPSRYFSMSFENN 1859

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
              S  + S+  QDSG+YT +  +  G +   A L V
Sbjct: 1860 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV 1895



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 75/372 (20%), Positives = 141/372 (37%), Gaps = 32/372 (8%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP+FV +L  +  V  G ++  EC++     P +R+ ++ N   L ++ ++ +TF     
Sbjct: 2087 PPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 2144

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP--EGLEKIR---- 2354
             + + +   ED+G++  +A N  G  +++ S  V  K   +  S  P  E L+       
Sbjct: 2145 VIQMNNLSTEDSGDFICEAQNPAG--STSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLE 2202

Query: 2355 -ELESAEPFK----RPEIPEPVTRQRPVFTQPLQ---NIDNIQEGQTAHFDCRLI-PVGD 2405
             EL    PF+    + +     +++  + ++      +I N+       + C+    VG 
Sbjct: 2203 CELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGS 2262

Query: 2406 PTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV------YMCRASNLLGE 2459
             T         KL E    ++K +    V+   + ++   EG       ++     ++ E
Sbjct: 2263 DTCVC----TVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRE 2318

Query: 2460 XXXXXXXXXXXXXXIQLETQHPEGMKK-IQKLEQPHERRSEEPDREFEKPIFTQVLTGPS 2518
                          +Q     P    K I +++     R         +P       GP 
Sbjct: 2319 SENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPM 2378

Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578
             +  G+    E +V   G P L  EWY +G  L    + + +      +L I SV   DA
Sbjct: 2379 TVTVGETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDA 2436

Query: 2579 GLYMCKAINRAG 2590
            G Y  +  N  G
Sbjct: 2437 GTYTFQVQNNVG 2448



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 23/66 (34%), Positives = 39/66 (59%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P L +EW+K+G  LT+  + K +F   + +L I S+   D+G YT +  N +G++  TA 
Sbjct: 2396 PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAV 2455

Query: 2732 IKIEDR 2737
            + + DR
Sbjct: 2456 VDVSDR 2461



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/146 (23%), Positives = 60/146 (41%), Gaps = 4/146 (2%)

Query: 1403 IAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESV-TIKPRFVTRPKSIENVIEGQH 1461
            I+   ++   +  +G    Q   +  +   T ++D S   + P F  R K+   V+ G  
Sbjct: 2423 ISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVL-GAS 2481

Query: 1462 VHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
               ECK+     S + V WF     +  G +++         L +  L + D G YTC A
Sbjct: 2482 CILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVA 2539

Query: 1522 VNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
             N+ G+DE    LT +     V+  +
Sbjct: 2540 ANVAGSDECRAVLTVQEPPSFVKEPE 2565



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 44/199 (22%), Positives = 81/199 (40%), Gaps = 10/199 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G     + WF   + +    R    +   +  LE+     + SG Y+C  +N  GQA  +
Sbjct: 2583 GTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCT 2642

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
             +L   + +   K R + H      ++ G+S   E T        + + W  +G  +  S
Sbjct: 2643 TRLFVKEPAAFLK-RLSDH-----SVEPGKSIILESTY--TGTLPISVTWKKDGFNITTS 2694

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPD 3255
             +   V+     +L+I  +   D+G+Y C   N+ G D   A ++   +   ++  L+P 
Sbjct: 2695 EKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTL-EPPYFVTELEPL 2753

Query: 3256 SLAKIRELESLQGAQQQTP 3274
              A + +  SLQ     TP
Sbjct: 2754 E-AAVGDSVSLQCQVAGTP 2771



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 2/90 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F+R L +IE   G  V L CRL   G   ++V W+ +G  ++     + ++  +   L
Sbjct: 2840 PSFARQLKDIEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDHENLQTSFVDNVATL 2897

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
             +L      SG Y+C A+N LG A +S  L
Sbjct: 2898 KILQTDLSHSGQYSCSASNPLGTASSSARL 2927



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 3/97 (3%)

Query: 633  VYPPPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V  PP+F+  L+ S  A +G  I  E +I   G P +K+ W +N   +  S ++   F  
Sbjct: 3025 VKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFIN 3082

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
                L +   + +DSG+Y C A +  G A     L V
Sbjct: 3083 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTV 3119



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/113 (28%), Positives = 48/113 (42%), Gaps = 3/113 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP FT    +      SS   EC++       + V WFH G  + +G + +T        
Sbjct: 4346 PPSFTRKLKETNGLSGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 4403

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGT 3669
            L +  + + D+G YTC ATN  G    S  L V+     + +P  P    +GT
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPD-PMDVLTGT 4455



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 52/228 (22%), Positives = 90/228 (39%), Gaps = 13/228 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F     D +D+  G    + +  I  G     + WF     +    R        + 
Sbjct: 4439 PPSFVQK-PDPMDVLTGTNVTFTS--IVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVA 4495

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LE+    T+ SG Y+C  +N+ G+A  +  L     +K     F   + N   ++ G+ 
Sbjct: 4496 ELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAK-----FVKRL-NDYSIEKGKP 4549

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               E T      P + + W  NG  +  S R    +     +L+I  +   D+G+Y C  
Sbjct: 4550 LILEGTFTGT--PPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYI 4607

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
             N  G+D   A I    +   +++ L+P  ++ + +  SLQ     TP
Sbjct: 4608 ENASGKDSCSAQILIL-EPPYFVKQLEPVKVS-VGDSASLQCQLAGTP 4653



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F + L  V A+ G    FE  +   G   +K+ W K+ + I +  ++   +      
Sbjct: 4817 PPFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAH 4874

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L +L ++  DSG+YTC AV+  G     A L++  R
Sbjct: 4875 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 4910



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   LK + +++G  I  E  +   G   + I+W K+ Q I AS ++   F      
Sbjct: 1339 PPSFTKKLKKMDSIKGSFIDLECIV--AGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 696  LDMLSLNIQDSGEYTCRAVSATG 718
            L++  L   DSG YTC A +  G
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAG 1419



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 3/130 (2%)

Query: 3249 LESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVP 3308
            L S + D+     E+E+  G         + EPP F+T+++ +   V G S   + ++  
Sbjct: 2711 LNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAV-GDSVSLQCQVAG 2769

Query: 3309 VDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDST 3368
               P++ V W+    KL     YRT+    +  L        +SGEY C A N +G  S+
Sbjct: 2770 T--PEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASS 2827

Query: 3369 KANLKCTSKE 3378
            K   +   ++
Sbjct: 2828 KTVFRIQERQ 2837



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G+SA +EC +     P MR+ W  + K ++ G  Y  +       L IL V   DSG+YT
Sbjct: 2950 GESADFECHVTG-AQP-MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYT 3007

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIR 1944
            C+A N++G+ + S +L+V+     ++
Sbjct: 3008 CQATNDVGKDMCSAQLSVKEPPKFVK 3033



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 2/97 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV   P F++    +  ++G++V L+C +   G     V W  + K ++   +F+   +
Sbjct: 3117 LTVKAPPVFTQKPSPVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSK 3174

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
                 L +L++   D G Y C+ATN++G    SC+++
Sbjct: 3175 HFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVK 3211



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 5/156 (3%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G   + I W+     + ++   +  +   +  L I     +D G YSC+A N  G    S
Sbjct: 3710 GTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASS 3769

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              L  V K++   P F   ++++     G    FEC  +   +P +++ WY +G  ++  
Sbjct: 3770 AVL--VIKARKLPPFFARKLKDVHETL-GFPVAFECR-INGSEP-LQVSWYKDGVLLKDD 3824

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ++T        L I  T     G+Y C A N  G
Sbjct: 3825 ANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLG 3860



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 3/110 (2%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   LK   + + G  V  E ++   ++P L++ W+K+GV L   A L+++F   + T
Sbjct: 3781 PFFARKLKDVHETL-GFPVAFECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVAT 3837

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLD 2751
            L I        G Y C A+N LG A S+A + + +        L P S+D
Sbjct: 3838 LQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVD 3887



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 64/264 (24%), Positives = 106/264 (40%), Gaps = 39/264 (14%)

Query: 1943 IRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLT 2002
            I  S  E A +   Y+E+ S  K +      ++E P F K ++  +V+ G    L+  L 
Sbjct: 4592 IPSSTVEDAGQYNCYIENASG-KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLA 4650

Query: 2003 PVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAV 2062
                P + V WY     ++    +K  +      L        D+G Y+CKA N+VGE  
Sbjct: 4651 --GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGE-- 4706

Query: 2063 TTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLK 2122
                  V A + L   T+ EQ+L        + R     +E  G   VF  A++      
Sbjct: 4707 ------VSASTFL---TVQEQKLP-----PSFSRQLRDVQETVGLPVVFDCAISG----- 4747

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
                       EPI+     + W+ +G+ ++     +T+       L+I  T    +G Y
Sbjct: 4748 ----------SEPIS-----VSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQY 4792

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRN 2206
             C ATN +G A ++  L +   +N
Sbjct: 4793 SCTATNPIGSASSSARLILTEGKN 4816



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/100 (33%), Positives = 52/100 (52%), Gaps = 4/100 (4%)

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
            +++EQ    P F R L+D+ E   G    F+  ++  S+P + V WYKDG+P+  S  + 
Sbjct: 4714 TVQEQKLP-PSFSRQLRDVQETV-GLPVVFDCAISG-SEP-ISVSWYKDGKPLKDSPNVQ 4769

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            + F     +LNI       AG Y+  A N +G A S+A +
Sbjct: 4770 TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    P F   ++D +    G    F+  +   G   + V W KDG+P++ S  + T 
Sbjct: 4715 VQEQKLPPSFSRQLRD-VQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNVQTS 4771

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
            F      L I       AG Y+C A N IG A++SA L +   K+
Sbjct: 4772 FLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN 4816



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 2/100 (2%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096
            V + + P F+  +  +  ++ G+SA    +++    + +T  W+ N K+++ +N ++ Y 
Sbjct: 396  VTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVT--WFKNNKELSESNTVRMYF 453

Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                  LDI  V+ EDSG Y+  A N  G    S  + ++
Sbjct: 454  VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK 493



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G++    C ++ S  P +++ WF NNK L      +     S   LDIT    EDSG Y+
Sbjct: 417  GESARLHCKLKGS--PVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYS 474

Query: 2848 CKATNSKGSATTS 2860
            C+A N  GS + S
Sbjct: 475  CEAVNDVGSDSCS 487



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K    FV+ L     + +G    L C++   G P +++ WF N R +   S+ +  +   
Sbjct: 961  KEPATFVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFVES 1018

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               L +      D+GEY   A N  GS H S+IV V E
Sbjct: 1019 TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKE 1056



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 2/100 (2%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            SV   P+FV + ++ +   +G+ +  ECK+    +  +KV WF+N   +    ++     
Sbjct: 3024 SVKEPPKFVKKLEASKVAKQGESIQLECKISGSPE--IKVSWFRNDSELHESWKYNMSFI 3081

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS 1538
                 L I +  AEDSG Y C A N VG    S  LT ++
Sbjct: 3082 NSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 3121



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 26/85 (30%), Positives = 48/85 (56%), Gaps = 3/85 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F  +P  IE  ++G  VH EC+L+     +  V W+K+ + +  G +++ + +    +
Sbjct: 4064 PIFRKKPHPIET-LKGADVHLECELQGTPPFH--VSWYKDKRELRSGKKYKIMSENFLTS 4120

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTD 1528
            + I+++ A D G Y C+A N VG+D
Sbjct: 4121 IHILNVDAADIGEYQCKATNDVGSD 4145



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 3/104 (2%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            + K+PP F  Q  +  ++ E E  +  C +   G   ++++W   G+ +   +R +  + 
Sbjct: 5006 EPKKPPVF-DQHLTPVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFA 5062

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             G   +    V   DSG+Y+C+A+N+ G D TK+ +    KP +
Sbjct: 5063 SGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV 5106



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 19/152 (12%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF  HL  +   EG+ +   C+V+ S +P ++I+W    + +    R   +       L+
Sbjct: 5012 VFDQHLTPVTVSEGEYVQLSCHVQGS-EP-IRIQWLKAGREIKPSDRCSFSFASGTAVLE 5069

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL-------------RCTGDKNIYFDTQHPQGK 2881
            +    + DSG Y CKA+N  GS TT   +             +   D  ++F    PQ  
Sbjct: 5070 LRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFF-VSEPQ-- 5126

Query: 2882 AGLEAVEQAEEARLAKGRRPSVPDTEYPKPEW 2913
              +  VE+     +AK     +P+ ++ K +W
Sbjct: 5127 -SIRVVEKTTATFIAKVGGDPIPNVKWTKGKW 5157



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 2/110 (1%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP  T  L+NV+         + ++       ++V W+ + K + +  R+      G  +
Sbjct: 777  APFFTKPLRNVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALP 1686
            L+I+     D+G +TCRA N++G   +SG  IV    S   +   +  LP
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLP 884



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L N+          +C +  S    +++ WF + K + +  RY+        SL+I
Sbjct: 780  FTKPLRNVDSVVNGTCRLDCKIAGSLP--MRVSWFKDGKEIAASDRYRIAFVEGTASLEI 837

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                  D+G +TC+ATNS GS  +SG+L
Sbjct: 838  IRVDMNDAGNFTCRATNSVGSKDSSGAL 865



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            VQ+ P F T   S D L  G  V L++  +  T   L I WFK    L +G     T + 
Sbjct: 867  VQEPPSFVTKPGSKDVL-PGSAVCLKSTFQGSTP--LTIRWFKGNKELVSGGSCYITKEA 923

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIG 2754
               +L +  ++  DSG YTCK +N+ G    +A++ +++    + E L P  L + G
Sbjct: 924  LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFV-EKLEPSQLLKKG 979



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/102 (23%), Positives = 53/102 (51%), Gaps = 4/102 (3%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V ++P F++    IE ++  +V L   +   G     + WF +   +++G +++   +
Sbjct: 1052 VIVKESPYFTKEFKPIEVLKEYDVMLLAEV--AGTPPFEITWFKDNTILRSGRKYKTFIQ 1109

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
               V+L +L     D+G Y C+ TN++G ++  C+ RV  ++
Sbjct: 1110 DHLVSLQILKFVAADAGEYQCRVTNEVGSSI--CSARVTLRE 1149



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 5/90 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   L  ++++K G     EC V   +   ++I WF + Q+I A  +Y+ +       
Sbjct: 1340 PSFTKKLKKMDSIK-GSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            L+I      DSGTY C ATNK G   N C+
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGH--NQCS 1424



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 2/71 (2%)

Query: 4110 PPVFVSLPDAVTV-EEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHF 4167
            PP F+  P  V V   G+   F C++TG PK RV W L+GN I    ++ +++ DG+  F
Sbjct: 1525 PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATF 1584

Query: 4168 DIPKTRQYDTG 4178
             I   R  ++G
Sbjct: 1585 QISGARVENSG 1595



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            ++ ++ P F   L  +E   G +V L+C  Q  G   + V W+     ++    +R  + 
Sbjct: 2738 VSTLEPPYFVTELEPLEAAVGDSVSLQC--QVAGTPEITVSWYKGDTKLRPTPEYRTYFT 2795

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +   L    V   DSG YTC+A N +G A +    R+
Sbjct: 2796 NNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRI 2833



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 4/110 (3%)

Query: 1307 VMQAPQFSRALHNIETVEGTN-VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
            V + P+F + L     V+       EC++   G   ++V W+ +   I+   +FR ++  
Sbjct: 3966 VQEPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVD 4023

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
                L++ ++  EDSG YTC+A N  G A +S +L+V  +  +  +  HP
Sbjct: 4024 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV-KEPPIFRKKPHP 4072



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P FT+ L+   E  EG     E RV   G   +   WY N +E++  S    T     + 
Sbjct: 4914 PSFTKRLSETVEETEGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 4971

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
            L +     NDAGLY CK  N AG
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAG 4994



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 36/160 (22%), Positives = 63/160 (39%), Gaps = 4/160 (2%)

Query: 3498 YNNYGEAVTTASMKVQGKRNIILESQLPKGME--GTIDKIAALEGYSGTVDTLTPEAESG 3555
            Y N  E   T++ ++  K N ++      GM   G      + +  S    +     E  
Sbjct: 4949 YKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPK 5008

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
             PP F    + + +SE       C +       +R++W   G+ +    R       G  
Sbjct: 5009 KPPVFDQHLTPVTVSEGEYVQLSCHV--QGSEPIRIQWLKAGREIKPSDRCSFSFASGTA 5066

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI 3655
            +LE+  V + D+G Y CKA+N  G  T   K+ +K +  +
Sbjct: 5067 VLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV 5106



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 57/232 (24%), Positives = 93/232 (40%), Gaps = 31/232 (13%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            ++ I ++EPK  PP F   L   T V EG+     C V+   +P +RI++   G+ ++ +
Sbjct: 4999 TSSIVIKEPK-KPPVFDQHLTPVT-VSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPS 5054

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPE 2348
             R   +F  G   L+++     D+G+Y  KA N  G  T+   +T+  K           
Sbjct: 5055 DRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDK----------- 5103

Query: 2349 GLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTL 2408
                        P   P   +     R  F    Q+I  + E  TA F  ++   GDP  
Sbjct: 5104 ------------PAVAPATKKAAVDGRLFFVSEPQSI-RVVEKTTATFIAKV--GGDPIP 5148

Query: 2409 KVEWFRNE-KLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             V+W + + + +    R+          + I      D G+Y C A N  GE
Sbjct: 5149 NVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGE 5200



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V EG++V   C ++      ++++W K G+ +    R       G   L++ D+   DSG
Sbjct: 5022 VSEGEYVQLSCHVQG--SEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSG 5079

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             Y C+A N+ G+D    ++T +    +  +T+  A
Sbjct: 5080 DYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAA 5114



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 53/227 (23%), Positives = 92/227 (40%), Gaps = 25/227 (11%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            P   T +Q+     +GQ A F+C V      D+K+ WY   + ++ S   +         
Sbjct: 10   PAIITPLQDTV-TSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ 65

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQG 3268
            L+IA     D G Y   A N  G+  + A ++        LE+  P+S+   R  + ++ 
Sbjct: 66   LEIAEAYPEDEGTYTFVANNAVGQVSSTANLS--------LEA--PESILHERIEQEIEM 115

Query: 3269 AQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG 3328
              +  P          I +  +  ++  G  A F   +     P+++ +WF  G+++   
Sbjct: 116  EMKAAP---------VIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYES 164

Query: 3329 HRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
             +        I  L+IL     + GEY C A+N+ G  S  A L  T
Sbjct: 165  DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 211



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 79/382 (20%), Positives = 141/382 (36%), Gaps = 26/382 (6%)

Query: 3273 TPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR 3332
            T +   A PP F+++ + +T  V G++A F   +     P ++  W  +G  L     +R
Sbjct: 207  TLTVTEAYPPTFLSRPKSLTTFV-GKAAKFICTVTGT--PVIETIWQKDGAALSPSPNWR 263

Query: 3333 TFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392
                    IL++     ++ G Y C A+NK G D  +A L    K + I + +    ++ 
Sbjct: 264  ISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELE---PVQS 320

Query: 3393 GLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNL 3452
             + K   LE  +   +  +V   K    +   P  + +   E + A  E  L    D   
Sbjct: 321  AINKKVHLECQVDEDRKVTVTWSKDGQKL--PPGKDYKICFEDKIATLEIPLAKLKDSGT 378

Query: 3453 KVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTY---PEDSGEYLCRAYNNYGEAVTTAS 3509
             V    N     + S   T  +    + ++ P+Y   P +S    C+   +    VT   
Sbjct: 379  YVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFK 438

Query: 3510 MKVQGKRNIILESQLPKG---MEGTIDKIAALEGYSGTV------DTLTPEAESGNPPEF 3560
               +   +  +          ++ T  K+     YS         D+ + E     PP F
Sbjct: 439  NNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSF 498

Query: 3561 --TTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILE 3618
              T  P+D++   N  A  +C +         + WF + K + +  + +  +    V LE
Sbjct: 499  IKTLEPADIVRGTN--ALLQCEV--SGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLE 554

Query: 3619 IGGVYQRDAGLYTCKATNRHGE 3640
            I      D G Y C   N  G+
Sbjct: 555  IFSFNSADVGEYECVVANEVGK 576



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 35/140 (25%), Positives = 59/140 (42%), Gaps = 7/140 (5%)

Query: 1790 ELGEAVTSSTLFVQSKASLQLESQ--HESALQKIQQLEDSSRYQRREDVEVAVNQAPRFI 1847
            EL E+ T    FV S+A L +      +S     + + D          E+ + + P FI
Sbjct: 442  ELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSC--STEIVIKEPPSFI 499

Query: 1848 TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL 1907
              L  P  +  G +A  +C +     P   + W+ + K ++S  +YR  +      L+I 
Sbjct: 500  KTLE-PADIVRGTNALLQCEVSG-TGP-FEISWFKDKKQIRSSKKYRLFSQKSLVCLEIF 556

Query: 1908 TVYGEDSGEYTCKAINNLGQ 1927
            +    D GEY C   N +G+
Sbjct: 557  SFNSADVGEYECVVANEVGK 576



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 2/107 (1%)

Query: 759 QESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
           Q S+ E   + P  I    +L ++  G  A  E   T    P ++ +WYKDGRP+ AS +
Sbjct: 670 QTSVGELIVKEPAKIIERAELIQVTAGDPATLE--YTVAGTPELKPKWYKDGRPLVASKK 727

Query: 819 ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
               F      L        D+G YT    N++G +    +  V  R
Sbjct: 728 YRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR 774



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 2/81 (2%)

Query: 2111 FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALD 2170
            F+  L   + LK+GD     C+V     P + I WF N ++I+   ++R +       L 
Sbjct: 966  FVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFVESTAVLR 1023

Query: 2171 ILYTYAEDSGTYMCKATNKLG 2191
            +     EDSG YMC+A N+ G
Sbjct: 1024 LTDVGIEDSGEYMCEAQNEAG 1044



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P  ++ WF +   L  G +Y+TF    +V L IL     ++GEY+C  TN++G     A 
Sbjct: 1085 PPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSAR 1144

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQ-TLEDSM 3404
            +      + I   +    + GG    Q TL+ S+
Sbjct: 1145 VTLREPPSFIKKIESTSSLRGGTAAFQATLKGSL 1178



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 32/115 (27%), Positives = 49/115 (42%), Gaps = 3/115 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGK-IHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V  PPQFI     V  +  G+   FE +I   G P +++ W  +G  I A  +    F  
Sbjct: 1522 VKEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFID 1579

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQY 746
            G  +  +    +++SG Y C A +  G A     L V    T  R  +  E ++Y
Sbjct: 1580 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKY 1634



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 10/130 (7%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP+F+ +      L   ++T FECQ+   G P ++V W+ +G  +    +    +  G
Sbjct: 1523 KEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFIDG 1580

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIE--KI 4087
                       E+SG Y+C A N  G       +K    P  +      + +K +E  K 
Sbjct: 1581 LATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFI------RELKPVEVVKY 1634

Query: 4088 REMEASWQVT 4097
             ++E   +VT
Sbjct: 1635 SDVELECEVT 1644



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 3/109 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F + L+    V  G +IH+EC++   G   +  +WF +G+ ++  ++++       V+
Sbjct: 1902 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAI 1285
            L++ +    DT  YT +  N  G    S I+ V E    +     +QAI
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAI 2007



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G +IH EC V  S    +  +WF + K + +  +Y+       VSL++ +   ED+  YT
Sbjct: 1916 GSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYT 1973

Query: 2848 CKATNSKGSATTSGSL 2863
            CK +N  G    SG L
Sbjct: 1974 CKVSNVAGDDACSGIL 1989



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 43/194 (22%), Positives = 83/194 (42%), Gaps = 12/194 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F++ F  IV+  +      E  L  +G     + W+ + + + +S + +        
Sbjct: 2181 PPVFSS-FPPIVETLKNAEVSLECEL--SGTPPFEVVWYKDKRQLRSSKKYKIASKNFHT 2237

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             + IL   T+D G Y C+A N+ G    S    C  K K + PRF + + ++  +  G+ 
Sbjct: 2238 SIHILNVDTSDIGEYHCKAQNEVG----SDTCVCTVKLK-EPPRFVSKLNSLTVVA-GEP 2291

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPM-RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            A  + ++       + ++W    + + R S  I+         L  A  +  ++G+Y+C+
Sbjct: 2292 AELQASIEGAQP--IFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQ 2349

Query: 3226 AYNKYGEDFTRATI 3239
              N  G     AT+
Sbjct: 2350 IKNDGGMRENMATL 2363



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/239 (24%), Positives = 101/239 (42%), Gaps = 40/239 (16%)

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            +P  +    G   +  G++   E +V    +L+  VEWY +GK +TS+ +    H F + 
Sbjct: 2367 EPAVIVEKAGPMTVTVGETCTLECKVAGTPELS--VEWYKDGKLLTSSQK----HKFSFY 2420

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161
               I+S+R     + +V       E Q + + T + ++++  SS        T  ++ S 
Sbjct: 2421 N-KISSLR-----ILSV-------ERQDAGTYTFQVQNNVGKSSC-------TAVVDVSD 2460

Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221
               P           P F + L N   V  G +  LEC++   G   + V WFH    + 
Sbjct: 2461 RAVP-----------PSFTRRLKNTGGVL-GASCILECKVA--GSSPISVAWFHEKTKIV 2506

Query: 1222 VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280
             G++++T +      L +    S+D G YT  A N  GS    A++ V E    V + +
Sbjct: 2507 SGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 2565



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 76/358 (21%), Positives = 137/358 (38%), Gaps = 44/358 (12%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    +V W +  R +    R   +F      L + ++ +  +G YTC   N  GQA+ +
Sbjct: 2583 GTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCT 2642

Query: 997  ANL---------------TIVTKKDIIAESQHPGGLE-KIQYLEDASRYSKRTEEEVKIT 1040
              L               ++   K II ES + G L   + + +D    +   +  +  T
Sbjct: 2643 TRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTT 2702

Query: 1041 QKPRFLGPLKGTNKIVEGQSAHF--EARVEPQSDLTMTVE-WYFNGKQITSANRIQTYHD 1097
            +K   L  L  T +     S     EA  +    L  T+E  YF    +T    ++    
Sbjct: 2703 EKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYF----VTELEPLEA--- 2755

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
                  D  S++ + +G   +      G+ +L    T E R+   T+++   ++ K    
Sbjct: 2756 ---AVGDSVSLQCQVAGTPEITVSWYKGDTKLRP--TPEYRTYF-TNNVATLVFNKVNIN 2809

Query: 1158 EESKFVEPMYQIEEISKSKPVF-VQPLSNPPPVSE---------GKNIHLECRLEPMGDP 1207
            +  ++          + SK VF +Q    PP  +          G  + L CRL   G  
Sbjct: 2810 DSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLN--GSA 2867

Query: 1208 TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             ++V W+ +G  +      +T +      L I+    + +G+Y+  A N LG+A +SA
Sbjct: 2868 PIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSA 2925



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 49/200 (24%), Positives = 83/200 (41%), Gaps = 40/200 (20%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G++  F C +   G   +K+ W ++ + I        T      ++T+  V   D G Y 
Sbjct: 3891 GESGTFKCHV--TGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYT 3948

Query: 2451 CRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIF 2510
            C ASN+ G+               QL  Q P   + I+KL         EP R  ++  F
Sbjct: 3949 CYASNIAGKDSCSA----------QLGVQEPP--RFIKKL---------EPSRIVKQDEF 3987

Query: 2511 TQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDI 2570
            T+               YE ++   G P ++  WY +  E++  S+FR +       L++
Sbjct: 3988 TR---------------YECKI--GGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 4030

Query: 2571 NSVVANDAGLYMCKAINRAG 2590
            +++   D+G Y C+A N AG
Sbjct: 4031 HNLSVEDSGDYTCEAHNAAG 4050



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 61/231 (26%), Positives = 91/231 (39%), Gaps = 30/231 (12%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P+F Q LT P  + EG++      V   G   +R +W   G E+K   R   +   G   
Sbjct: 5011 PVFDQHLT-PVTVSEGEYVQLSCHVQ--GSEPIRIQWLKAGREIKPSDRCSFSFASGTAV 5067

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L++  V   D+G Y+CKA N AG                       +S   I+ K A   
Sbjct: 5068 LELRDVAKADSGDYVCKASNVAGSDTT-------------------KSKVTIKDKPAVAP 5108

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFK-NGVTLT 2686
               +  VD  +     F +  +S  ++VE       A+V     PN+K  W K     L 
Sbjct: 5109 ATKKAAVDGRL----FFVSEPQSI-RVVEKTTATFIAKVGGDPIPNVK--WTKGKWRQLN 5161

Query: 2687 TGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             G R+          L I      DSG+Y C A N  GE  S  ++++++R
Sbjct: 5162 QGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 5212



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)

Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ 1093
            + E+ I  KP F+  L+     +  +  H E +V+   D  +TV W  +G+++      +
Sbjct: 300  QAELIIIDKPHFIKELEPVQSAIN-KKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYK 356

Query: 1094 TYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
               +     L+I   + +DSG Y   A N AG +  SA++TV
Sbjct: 357  ICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 398



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 48/259 (18%), Positives = 104/259 (40%), Gaps = 10/259 (3%)

Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           V+W++    L     Y + + ++   + + + ++   D G Y CTA N+ G + CS  + 
Sbjct: 340 VTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLK--DSGTYVCTASNEAGSSSCSATVT 397

Query: 163 P-EGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF 221
             E                  S  +  K  G+        +  ++++ +N     +   +
Sbjct: 398 VREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESN-----TVRMY 452

Query: 222 KVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGA 281
            V++     + +V   +S +      +DV  S      +    PP   +    + +  G 
Sbjct: 453 FVNSEAILDITDVKVEDSGSYSCEAVNDVG-SDSCSTEIVIKEPPSFIKTLEPADIVRGT 511

Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAE 341
           +A  Q ++SG     ++WFK+ +++ +S K+ + +  +   L + +   +D G Y  +  
Sbjct: 512 NALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVA 571

Query: 342 NPNG-CIVTSGYLAVESPT 359
           N  G C   + +L  E PT
Sbjct: 572 NEVGKCGCMATHLLKEPPT 590



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 2/102 (1%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P FT    ++    N +   +C++       MRV WF +GK +    R +     G   L
Sbjct: 778  PFFTKPLRNVDSVVNGTCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 835

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            EI  V   DAG +TC+ATN  G    S  L V+     + +P
Sbjct: 836  EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKP 877



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 21/76 (27%), Positives = 39/76 (51%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ WFK+   +  G +++       V+L I+  +A D+G Y CR  N VG+   S R+T 
Sbjct: 1088 EITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTL 1147

Query: 1537 RSTTDIVRSTQNEAGL 1552
            R     ++  ++ + L
Sbjct: 1148 REPPSFIKKIESTSSL 1163



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + P+F+        +  GQS  FE ++     +   V WY +G +IT+  +       
Sbjct: 1522 VKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIR--VSWYLDGNEITAIQKHGISFID 1579

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            G     I+  R E+SG Y   ARN AG A  S  + V+
Sbjct: 1580 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 1617



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 2/103 (1%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F+R L N   V G +  LEC++   G   + V WF     I +G +++  +  +   L
Sbjct: 2465 PSFTRRLKNTGGVLGASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTL 2522

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQ 1413
             L S+   D G YTC A N  G       L V      + E +
Sbjct: 2523 QLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 2565



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 3262 ELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321
            E  +  G+   + S    EPP F  +   +  L +G   H E  L     P   V W+ +
Sbjct: 4044 EAHNAAGSASSSTSLKVKEPPIFRKKPHPIETL-KGADVHLECELQGT--PPFHVSWYKD 4100

Query: 3322 GKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDS 3367
             ++L  G +Y+   +  +  + IL     + GEY+C ATN +G D+
Sbjct: 4101 KRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDT 4146



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 27/105 (25%), Positives = 55/105 (52%), Gaps = 8/105 (7%)

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            T  V E  T+++ P+      +I+   G    LEC +   G   +  +WF +GK + + +
Sbjct: 4244 TLSVLEPATIVEKPE------SIKVTTGDTCTLECTV--AGTPELSTKWFKDGKELTSDN 4295

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +++ ++      L +++V P DSGVY+ +  N +G+   + +L+V
Sbjct: 4296 KYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV 4340



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 12/140 (8%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVD 3142
            EWF NG+ ++   R +T     +  L I   +  D G Y+C+  +    AE+ ++ E + 
Sbjct: 5441 EWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPI- 5499

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
                   +FT  IQNI  + + QSA FEC    V   D  + WY     +  S +    +
Sbjct: 5500 -------QFTKRIQNIV-VSEHQSATFEC---EVSFDDAIVTWYKGPTELTESQKYNFRN 5548

Query: 3203 DFGFVVLDIAYTQNHDSGEY 3222
            D     + I      D G Y
Sbjct: 5549 DGRCHYMTIHNVTPDDEGVY 5568



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 21/68 (30%), Positives = 33/68 (48%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L+ +W KDGRP+ AS +    F      L   S  +HD+G YT    N +G ++  
Sbjct: 707  GTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCE 766

Query: 997  ANLTIVTK 1004
               T++ +
Sbjct: 767  TTFTVLDR 774



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 3/106 (2%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            +D+   P F   +++  S+V   T + +C++A  G   M+V WF +GK +   +R+   +
Sbjct: 772  LDRDIAPFFTKPLRNVDSVVN-GTCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAF 828

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
              G  ++    V   D+G + CRATN  G  ++   +     P  V
Sbjct: 829  VEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFV 874



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 3/101 (2%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F  PL+  + +V G +   + ++     L M V W+ +GK+I +++R +     G  +
Sbjct: 778  PFFTKPLRNVDSVVNG-TCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
            L+I  V   D+G +T  A N+ G    S ++ V+   S  T
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVT 875



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 3/83 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   L +++++  G     +C++       + + WF +G++I A  RYR     G  +
Sbjct: 778  PFFTKPLRNVDSVVNGT-CRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L+I+     D+G + C+ATN +G
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVG 857



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F   +K   SIK G F   E  +   G   + ++W KD + + AS +    F+     
Sbjct: 1340 PSFTKKLKKMDSIK-GSFIDLECIVA--GSHPISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I  +   D+G YTC A N  G    S +LT+
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV 1429



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L  +   +G  I  EC V  S    + I+WF +++ + +  +YK +   +   L+I
Sbjct: 1342 FTKKLKKMDSIKGSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDNTAFLEI 1399

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            +     DSG YTC ATN  G    SG L
Sbjct: 1400 SQLEGTDSGTYTCSATNKAGHNQCSGHL 1427



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 22/94 (23%), Positives = 46/94 (48%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   ++ +  ++ + +D + + +++G P   VTW KN + + +S K+ +    +   L 
Sbjct: 1619 PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLH 1678

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            +     SD+G Y  +  N  G    S  +A++ P
Sbjct: 1679 ITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEP 1712



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 2/99 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP FI  +++ T +      F++ +   G P + I WLK+ Q ++        F     +
Sbjct: 1712 PPSFIKKIENTTTVLKSSATFQSTV--AGSPPISITWLKDDQILDEDDNVYISFVDSVAT 1769

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            L + S++   SG YTC+A + +GV    A L V   A I
Sbjct: 1770 LQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQI 1808



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 41/154 (26%), Positives = 62/154 (40%), Gaps = 5/154 (3%)

Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA--PICTTSLKNVEIKEGQRA 1595
            S+  I+   + +AG    QV  +  K   T +VD V+ +A  P  T  LKN     G   
Sbjct: 2424 SSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVD-VSDRAVPPSFTRRLKNTGGVLGASC 2482

Query: 1596 HFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAI 1655
              E ++     + + V W+H    + SG+++  T +     L + S    D G YTC A 
Sbjct: 2483 ILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAA 2540

Query: 1656 NALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN 1689
            N  G      +  V    S   E +    LP  N
Sbjct: 2541 NVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKN 2574



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P+F   ++     K+G     E ++   G   ++V W ++   +  S +    F    
Sbjct: 3027 EPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSV 3084

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              LTI   +  D+G Y C A+N +G A+ S  LT+
Sbjct: 3085 ALLTINEASAEDSGDYICEAHNGVGDASCSTALTV 3119



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 79/381 (20%), Positives = 147/381 (38%), Gaps = 27/381 (7%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   P  + L+   S  F+C +     + +++ W  + + +  G   K         
Sbjct: 3876 PPFFDLKPVSVDLALGESGTFKCHV--TGTAPIKITWAKDNREIRPGGNYKMTLVENTAT 3933

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L +  V + DAG YTC A+N  G+ + S +L V+     I + + PS      E   + E
Sbjct: 3934 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLE-PSRIVKQDE-FTRYE 3991

Query: 3677 ETLHKREEITI-----EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731
              +    EI +     E E     +F +   D++ V E   +H +  VE  GD T     
Sbjct: 3992 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLE---MH-NLSVEDSGDYTCEAHN 4047

Query: 3732 FHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAG-EYTCRATNKWGSATTTAK--ITCS 3788
                   +T  +V     F      I+ +   D   E   + T  +  +    K  +   
Sbjct: 4048 AAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSG 4107

Query: 3789 AKRDIVLESQLPQ----GMSGEKIKELERGRISDAPKEEPI----VSTPPKFITQIKSHT 3840
             K  I+ E+ L       +    I E +    +D   +  +    +  PP+F+ ++   +
Sbjct: 4108 KKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDIS 4167

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRN-GKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899
                + V+ +  +E  E   + + W+++ G+++         Y     +L    V   ++
Sbjct: 4168 TVVGKEVQLQTTIEGAE--PISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANA 4225

Query: 3900 GEYICRAVNDFGEDFTKATIS 3920
            G+Y C+  ND G     AT+S
Sbjct: 4226 GKYTCQIKNDAGMQECFATLS 4246



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 2/85 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  G    LE  V     P L  +WFK+G  LT+  + K +F   +  L I ++   DS
Sbjct: 4261 KVTTGDTCTLECTVAGT--PELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDS 4318

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDR 2737
            G+Y+ +  N +G+   TAS+++ DR
Sbjct: 4319 GVYSFEVQNPVGKDSCTASLQVSDR 4343



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+     +  + V+LE QV+   D  + + W K+G  L  G   K  F+  + T
Sbjct: 309  PHFIKELEPVQSAIN-KKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIAT 365

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L I   +  DSG Y C A+N  G +  +A++ + +
Sbjct: 366  LEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE 400



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++   F + L+    +++G      C++   G P +K+ WF N++ I++SS+   +    
Sbjct: 961  KEPATFVEKLEPSQLLKKGDATQLACKV--TGTPPIKITWFANDREIKESSKHRMSFVES 1018

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
               + ++ V  ED G YMC A N  G
Sbjct: 1019 TAVLRLTDVGIEDSGEYMCEAQNEAG 1044



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PVF +    +E LK  +    EC +     P   + W+ + +++R+  +Y+      + +
Sbjct: 2182 PVFSSFPPIVETLKNAE-VSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNFHTS 2238

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            + IL     D G Y CKA N++G     CT+K+
Sbjct: 2239 IHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL 2271



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 3/115 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP FT  +K+   V  G     +C+V   G   + + WFH      +G++  T       
Sbjct: 2464 PPSFTRRLKNTGGVL-GASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVC 2520

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
             L ++ + + D G YTC A N  GS    A +T       V E +  + + G+ +
Sbjct: 2521 TLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNV 2575



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 4/102 (3%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P F +   ++E + G ++     ++  G    +V+WF   + +  G     + E
Sbjct: 3493 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIR--GTPPFKVKWFKGSRELVPGESCNISLE 3550

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
                 L+L  V P +SG Y+C  TN  G A  SC   +  K+
Sbjct: 3551 DFVTELELFEVQPLESGDYSCLVTNDAGSA--SCTTHLFVKE 3590



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 3/98 (3%)

Query: 1707 ITQAPVFTMPMKDIRVA-ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + P F   ++  R+  +++   +E ++   G P+++V W ++   I+ S++       
Sbjct: 3966 VQEPPRFIKKLEPSRIVKQDEFTRYECKI--GGSPEIKVLWYKDETEIQESSKFRMSFVD 4023

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
                L M  ++ EDSG YTC A N  G A +S++L V+
Sbjct: 4024 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 4061



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 23/94 (24%), Positives = 49/94 (52%), Gaps = 2/94 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP+FI +++    + + +   +E ++     P++KV W+ +  ++    ++R      +
Sbjct: 3968 EPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDSV 4025

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
             +L++     E+SG+Y C A N  G  S+  +LK
Sbjct: 4026 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLK 4059



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 5/116 (4%)

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            +E+ S     SAQ  +I + P F   ++ ++V+   +A  + +L   G P++ V W +  
Sbjct: 4607 IENASGKDSCSAQI-LILEPPYFVKQLEPVKVSVGDSASLQCQL--AGTPEIGVSWYKGD 4663

Query: 1751 VPIEASNRLTTMHDFGYVA-LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
              +  +     MH    VA L    V+  DSG Y C+A N +GE   S+ L VQ +
Sbjct: 4664 TKLRPTTTYK-MHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 4718



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +    V+EG  V L   +   ++P +R++W   GR ++   R   ++  G   L
Sbjct: 5011 PVFDQHLTPVTVSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVL 5068

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            ++      D+G Y+CKA+N  G   T S V +  K
Sbjct: 5069 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDK 5103



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            R+ P F + +     +  G++A   C+L   G P ++V WF+N K + +S+ +       
Sbjct: 399  REPPSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVNS 456

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
               + I+ V+ ED G Y C A N +G
Sbjct: 457  EAILDITDVKVEDSGSYSCEAVNDVG 482



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 26/120 (21%), Positives = 53/120 (44%), Gaps = 2/120 (1%)

Query: 1700 HSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            H +   ++ ++P FT   K I V +       A +   G P   + W ++   + +  + 
Sbjct: 1047 HCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEV--AGTPPFEITWFKDNTILRSGRKY 1104

Query: 1760 TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
             T      V+L +      D+G Y CR  NE+G ++ S+ + ++   S   + +  S+L+
Sbjct: 1105 KTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLR 1164



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 17/164 (10%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
            +IE +   PP F  E+K  ++V +   V  +C V   G P   + W  N R   + S+ +
Sbjct: 1611 SIELKVKEPPTFIRELKP-VEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRS-SKKY 1666

Query: 3746 TLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
            TL D      L I      D GEY C  +N+ GS + + ++        +          
Sbjct: 1667 TLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFI---------- 1716

Query: 3805 GEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV-EESEGV 3847
             +KI+       S A  +  +  +PP  IT +K   + +E + V
Sbjct: 1717 -KKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNV 1759



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/107 (28%), Positives = 54/107 (50%), Gaps = 6/107 (5%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR-TFCDFGFV 3478
            P F   L   + ++ G+++  E ++  +  P ++V W+ N   L A  ++R TF D    
Sbjct: 2088 PKFVKKLEASKIVKAGDSSRLECKIAGS--PEIRVVWFRNEHELPASDKYRMTFID-SVA 2144

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLP 3525
            +++++    EDSG+++C A N  G   T+ S KV  K   +  S  P
Sbjct: 2145 VIQMNNLSTEDSGDFICEAQNPAGS--TSCSTKVIVKEPPVFSSFPP 2189



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 3/98 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K+ PVF Q  S P    +G ++ L+C +   G P   V W  + + V    +FK      
Sbjct: 3120 KAPPVFTQKPS-PVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHF 3176

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               L I++  ++D GEY  +A N +GS   S  V+  E
Sbjct: 3177 DTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE 3214



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D+  PP F+ +++   +++       EC+++  G   + V WF +G  ++   +    + 
Sbjct: 3401 DRIVPPSFIRKLKDVNAILGASVV-LECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFS 3457

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
                 +N   + P D+G Y C A N+ G DE  AV+     P
Sbjct: 3458 ENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPP 3499



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  ++KD ++   G  V  +CRV   G   + + WF +G    +G +  +       
Sbjct: 3405 PPSFIRKLKD-VNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVC 3461

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             L++  +   D G YTC A N  GS   +A +T
Sbjct: 3462 TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLT 3494



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/96 (26%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++PL +   V  G+   L+C+++  G P +R+ W+     +     +K  +     +
Sbjct: 3685 PYFIEPLEHVEAVI-GEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVAS 3741

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            L I     +D GEY+ +A N +G+  +SA++ +  R
Sbjct: 3742 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR 3777



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/101 (24%), Positives = 52/101 (51%), Gaps = 2/101 (1%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ + + PRF+  L+ +  + + +   +E ++    ++   V WY +  +I  +++ +  
Sbjct: 3963 QLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIK--VLWYKDETEIQESSKFRMS 4020

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                   L++ ++  EDSG YT  A NAAG A  S S+ V+
Sbjct: 4021 FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 4061



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L     +K+ +   +EC++     P + + W+ +  +I+   ++R +       
Sbjct: 3970 PRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDSVAV 4027

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L++     EDSG Y C+A N  G A ++ +LKV
Sbjct: 4028 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 4060



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/112 (24%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E    P F   + + +   EG     E R+   G   + V W K+   ++ +S     
Sbjct: 4907 IKERLIPPSFTKRLSETVEETEGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEIT 4964

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            F    + L ++   ++DAG YTC+  N  G A  ++++ I   K      QH
Sbjct: 4965 FKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH 5016



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPI-KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            P F K + +  E TEG+   LE  +       + V WY N   +Q     + T+    + 
Sbjct: 4914 PSFTKRLSETVEETEGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 4971

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +  A   D G Y CK +N  G A+ TSS+ +
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVI 5004



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 6/110 (5%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            L EGQ+     +   +  PN++ EW+ NG++L+   R++T  +     L I  V  ED G
Sbjct: 5421 LKEGQTCTMTVQ---FSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQG 5477

Query: 1916 EYTCKAINNLGQAVSSIRLN-VQSKESI--IRDSQHESALEKIQYLEDDS 1962
            +YTCK  +    A   I    +Q  + I  I  S+H+SA  + +   DD+
Sbjct: 5478 QYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDA 5527



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 3/115 (2%)

Query: 1694 TSKYQRHSAQDE-VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVP 1752
            ++K+     Q E +I   P F   ++ ++ A N+  H E ++    D K+ V W ++G  
Sbjct: 291  SNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDE--DRKVTVTWSKDGQK 348

Query: 1753 IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            +          +     L +     +DSGTY C A NE G +  S+T+ V+   S
Sbjct: 349  LPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS 403



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 2/81 (2%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F   L   + L++G+      ++T T  P +K+ W+ N + +K  S+ R        +L 
Sbjct: 966  FVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVESTAVLR 1023

Query: 3482 ISPTYPEDSGEYLCRAYNNYG 3502
            ++    EDSGEY+C A N  G
Sbjct: 1024 LTDVGIEDSGEYMCEAQNEAG 1044



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 2/99 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F         L  GQ    E Q+     P +++ W+ +G  +T   +   +F  
Sbjct: 1522 VKEPPQFIKKPSPVLVLRNGQSTTFECQITGT--PKIRVSWYLDGNEITAIQKHGISFID 1579

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            GL T  I+  R ++SG Y C+A N  G A  +  +K+++
Sbjct: 1580 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKE 1618



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 3/119 (2%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            +E+ V + P FI +L  P ++ +      EC +   P     V W  N + ++S  +Y  
Sbjct: 1612 IELKVKEPPTFIRELK-PVEVVKYSDVELECEVTGTPP--FEVTWLKNNREIRSSKKYTL 1668

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
            ++      L I      D+GEY C   N  G    S R+ ++   S I+  ++ + + K
Sbjct: 1669 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLK 1727



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 43/191 (22%), Positives = 72/191 (37%), Gaps = 11/191 (5%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP FT     + D   G   H E  +  +G   +  +WF +GK I  S + R V  
Sbjct: 1897 DQNIPPSFTKKLTKM-DKVLGSSIHMECKV--SGSLPISAQWFKDGKEISTSAKYRLVCH 1953

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               V LE+   +  D+  Y+C+ +N  G    S  L     +  + P F       + + 
Sbjct: 1954 ERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGIL-----TVKEPPSFLVKPGRQQAIP 2008

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            D   +  E   +    P  KI+W+ +   +    +     +     L++       +G+Y
Sbjct: 2009 D---STVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQY 2065

Query: 3223 VCRAYNKYGED 3233
             C   N  G D
Sbjct: 2066 TCHVTNDVGSD 2076



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   LK+   + G     E ++   G   + + W      I + +++ + F     +
Sbjct: 2464 PPSFTRRLKNTGGVLGASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCT 2521

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + SL+  D G YTC A +  G  E +AVL V
Sbjct: 2522 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV 2554



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 68/388 (17%), Positives = 153/388 (39%), Gaps = 31/388 (7%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ + + P+F+  L+ +    +G+S   E ++    ++   V W+ N  ++  + +    
Sbjct: 3022 QLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIK--VSWFRNDSELHESWKYNMS 3079

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTR 1155
                   L I    AEDSG Y   A N  G+A  S ++TV+            G  + + 
Sbjct: 3080 FINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSD 3139

Query: 1156 HIEESKFV-EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH-LECRLEPMGDPTMRVEW 1213
             I + +    P +++  +   K V               N+H L      +G+   +   
Sbjct: 3140 VILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATN 3199

Query: 1214 FHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGE-YTVRAVNHLGSAHTSAIVRVIER 1272
                 + +   +FK    F    +  +  TS   G+   +RA+  +      ++V + +R
Sbjct: 3200 EVGSDTCSCSVKFKEPPRF----VKKLSDTSTLIGDAVELRAI--VEGFQPISVVWLKDR 3253

Query: 1273 SDIVTDTQNEQA--IEQIQLLE----DAARRTK---QVRED---------ITVMQAPQFS 1314
             +++ +++N +   I+ I  L+    +A+   K   Q++ D         +TV++  +  
Sbjct: 3254 GEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARII 3313

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
                 +    G    LEC +   G   +  +WF +G+ +    +    +     +L +  
Sbjct: 3314 EKPEPMTVTTGNPFALECVV--TGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPC 3371

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                D G+Y+ +  N +G++  + ++ V
Sbjct: 3372 AEMSDKGLYSFEVKNSVGKSNCTVSVHV 3399



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 3/95 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++ L +   +  G ++ LECR+   G   + V WF +G  +  G + ++ +      
Sbjct: 3406 PSFIRKLKDVNAIL-GASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            L++     +DTG YT  A N  GS   SA++ V E
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE 3497



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L ++    G+    +C V+ +  P ++I W+  +  L S   YK     +  SL I
Sbjct: 3687 FIEPLEHVEAVIGEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 3744

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                  D G Y+CKA NS G+  +S  L
Sbjct: 3745 NKVDHSDVGEYSCKADNSVGAVASSAVL 3772



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 3/95 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  ++KD +    G PV F+CR+   G   +++ W+ +G      + + T       
Sbjct: 3780 PPFFARKLKD-VHETLGFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHNVA 3836

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
             L I        G+Y C A+N  G+A+++AK+  S
Sbjct: 3837 TLQILQTDQSHIGQYNCSASNPLGTASSSAKLILS 3871



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/97 (26%), Positives = 50/97 (51%), Gaps = 3/97 (3%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHP-VHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P+F K ++ + + +       E  +     P ++V WY +   +Q+  +F+ ++  
Sbjct: 3966 VQEPPRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVD 4023

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L++     ED+G Y C+A NA G A +++S+KV
Sbjct: 4024 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 4060



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 2/91 (2%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PRF+ + +    V + +   +ECK+    +  +KV W+K+   +    +FR         
Sbjct: 3970 PRFIKKLEPSRIVKQDEFTRYECKIGGSPE--IKVLWYKDETEIQESSKFRMSFVDSVAV 4027

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L++ +L  EDSG YTC A N  G+   S  L
Sbjct: 4028 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSL 4058



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 32/128 (25%), Positives = 61/128 (47%), Gaps = 6/128 (4%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G+ P F     +  +   G+ A FEC V       + + W  + ++IR+G +Y+ ++   
Sbjct: 4814 GKNPPFFDIRLAPVDAVVGESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLEN 4871

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225
               L +L     DSG Y C A N++G+  ++CT ++     +I  +      E +   E 
Sbjct: 4872 SAHLTVLKVDKGDSGQYTCYAVNEVGK--DSCTAQLNIKERLIPPSFTKRLSETVE--ET 4927

Query: 2226 QGHSTRIE 2233
            +G+S ++E
Sbjct: 4928 EGNSFKLE 4935



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P +  HL+    L EGQ   +  Q      PN+K EWF+NG  L    R K+  +  +  
Sbjct: 5410 PAWERHLQDVT-LKEGQTCTMTVQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHK 5465

Query: 2702 LSINSLRNDDSGIYTCKATNL 2722
            L+I  +R +D G YTCK  +L
Sbjct: 5466 LTIADVRAEDQGQYTCKYEDL 5486



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 2/95 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   +     +  G  A    +L+  G   ++V W K+ + +  S+ +  +F    
Sbjct: 400  EPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSE 457

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              L I  V V D+G Y+C A N +G  + S  + I
Sbjct: 458  AILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI 492



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 3557 PPEFT--TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP F     PS L+L    SA   C+L       ++V WF N K L   + V+       
Sbjct: 401  PPSFVKKVDPSYLMLP-GESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVNSE 457

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
             IL+I  V   D+G Y+C+A N  G  + S ++ +K     I   + P+    GT ++ +
Sbjct: 458  AILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLE-PADIVRGTNALLQ 516

Query: 3675 LE 3676
             E
Sbjct: 517  CE 518



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845
            K+GD     C V  +  P +KI WF N++ +   ++++ +   S   L +T    EDSG 
Sbjct: 977  KKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGE 1034

Query: 2846 YTCKATNSKGS 2856
            Y C+A N  GS
Sbjct: 1035 YMCEAQNEAGS 1045



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 3/117 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP+F+ +      +  G++  FECQ+     P +R+ +Y +G  + +  +  I+F  G  
Sbjct: 1525 PPQFIKKPSPVLVLRNGQSTTFECQITGT--PKIRVSWYLDGNEITAIQKHGISFIDGLA 1582

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELE 2357
            +  I     E++G Y  +A N  G  + +I + V    + I E  +P  + K  ++E
Sbjct: 1583 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE-LKPVEVVKYSDVE 1638



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V +  Q      +++  E   + LEC +   G   ++V+W  +GK I     F  ++E
Sbjct: 1800 LLVQEPAQIVEKAKSVDVTEKDPMTLECVV--AGTPELKVKWLKDGKQIVPSRYFSMSFE 1857

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             +  +  + SV  +DSG YT +  N  G +     LRV+
Sbjct: 1858 NNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVL 1896



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 26/94 (27%), Positives = 50/94 (53%), Gaps = 3/94 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L   +K++ G S H E +V     L ++ +W+ +GK+I+++ + +       V+
Sbjct: 1902 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            L++ ++  ED+  YT    N AG+   S  +TV+
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 1992



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 5/101 (4%)

Query: 633  VYPPPQFIVPLKSVTAMEGG-KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V  PP+F+  L++   ++ G     E +I   G P +++ W +N   + AS ++   F  
Sbjct: 2084 VTEPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFID 2141

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATG--VAETKAVLHVTP 730
                + M +L+ +DSG++ C A +  G     TK ++   P
Sbjct: 2142 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 2182



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FV+ L     V  G +  LEC++   G P +RV WF N   +    +++  +      
Sbjct: 2088 PKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDSVAV 2145

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            + + + ++ D+G++   A N  GS   S  V V E
Sbjct: 2146 IQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE 2180



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 43/136 (31%), Positives = 59/136 (43%), Gaps = 6/136 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            E    P F   P  + +    SA FEC +       MR+ W  + K +  G    TI   
Sbjct: 2931 EPKKSPFFDIKPVSIDVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNY-TITCV 2987

Query: 3613 GFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES 3671
            G    L I  V + D+G YTC+ATN  G+   S +L VK     + + +     K G ES
Sbjct: 2988 GNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQG-ES 3046

Query: 3672 IQKLEETLHKREEITI 3687
            IQ LE  +    EI +
Sbjct: 3047 IQ-LECKISGSPEIKV 3061



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 3/99 (3%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474
            E  K+P F +   +I+ +  GE+A FE  +T      +++ W  + K ++ G  +   C 
Sbjct: 2931 EPKKSPFFDIKPVSIDVIA-GESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCV 2987

Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
                 L I      DSG+Y C+A N+ G+ + +A + V+
Sbjct: 2988 GNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 3026



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 2/97 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI ++K         V  ECRV       + + W+++G  + SG + ++ +     +
Sbjct: 3405 PPSFIRKLKDVNAILGASVVLECRVSGSAP--ISVGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L++  +   D+G Y C A N  G D   A ++ ++ P
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPP 3499



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 2/99 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +KD+      +   E R+   G   + V W ++G  I +  +  +        L
Sbjct: 3406 PSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 3463

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQ 1809
            N+  + P D+G YTC A N  G    S+ L VQ   S +
Sbjct: 3464 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFE 3502



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/102 (24%), Positives = 52/102 (50%), Gaps = 3/102 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++ + T G PV  +  ++  ++P + V WY +G+P++     +T++      L
Sbjct: 4722 PSFSRQLRDVQETVGLPVVFDCAISG-SEP-ISVSWYKDGKPLKDSPNVQTSFLDNTATL 4779

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSS-VKVDAKSGLYLD 2078
            +I        G Y C ATN +G A +++  +  + K+  + D
Sbjct: 4780 NIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFD 4821



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 3/103 (2%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            KP +I  +      +  +V HLE QV+   D  + + W  +G+ L  G  +K+  +    
Sbjct: 308  KPHFIKELEPVQSAINKKV-HLECQVD--EDRKVTVTWSKDGQKLPPGKDYKICFEDKIA 364

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
            TL++     +DSG Y C A N+ G +  S+TV      + +++
Sbjct: 365  TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKK 407



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 44/152 (28%), Positives = 66/152 (43%), Gaps = 13/152 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P FVT+P S ++V+ G  V  +   +  T   L + WFK  + +  G       +    +
Sbjct: 871  PSFVTKPGS-KDVLPGSAVCLKSTFQGSTP--LTIRWFKGNKELVSGGSCYITKEALESS 927

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L++  +   DSG YTC+  N+ G  E S  L  +     V        LE  Q+L+   K
Sbjct: 928  LELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEK------LEPSQLLK---K 978

Query: 1564 YHRTDMVDEVTTQAPICTTSLKN-VEIKEGQR 1594
               T +  +VT   PI  T   N  EIKE  +
Sbjct: 979  GDATQLACKVTGTPPIKITWFANDREIKESSK 1010



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   I+   S++ GG A F+A L+  G   + V WLKD   +     I   F    
Sbjct: 1149 EPPSFIKKIESTSSLR-GGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTFENNV 1205

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011
             +L +  + V   G Y C+A N  G    SA L++     I  E+
Sbjct: 1206 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEA 1250



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 9/135 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+  +  S + P  IT+      + +G  A  + +     +  +  +WF +G++L  G +
Sbjct: 1232 QRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKE--ITAKWFKDGQELTLGSK 1289

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGM 3390
            Y+      + IL I+   +++SGEY     N +GR S KA +        +LD  +P   
Sbjct: 1290 YKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARIN-------VLDLIIPPSF 1342

Query: 3391 EGGLEKLQTLEDSMV 3405
               L+K+ +++ S +
Sbjct: 1343 TKKLKKMDSIKGSFI 1357



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 9/140 (6%)

Query: 1134 TVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGK 1193
            T++ RS +D    H G Y  T   +    VE  Y    +   +P  +   +    V+E  
Sbjct: 1769 TLQIRS-VDNG--HSGRY--TCQAKNESGVERCYAF--LLVQEPAQIVEKAKSVDVTEKD 1821

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
             + LEC +   G P ++V+W  +G+ +     F   ++    +  I      D+G+YT +
Sbjct: 1822 PMTLECVVA--GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFK 1879

Query: 1254 AVNHLGSAHTSAIVRVIERS 1273
              N  GS+   A +RV++++
Sbjct: 1880 VENDFGSSSCDAYLRVLDQN 1899



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 22/93 (23%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP FT ++   +D   G  +H +C+V   G   +   WF +G+  +T ++   +     +
Sbjct: 1901 PPSFTKKLT-KMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSV 1957

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L+++ +   D   YTC+ +N  G    +  +T
Sbjct: 1958 SLEVNNLELEDTANYTCKVSNVAGDDACSGILT 1990



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 24/99 (24%), Positives = 48/99 (48%), Gaps = 3/99 (3%)

Query: 1706 VITQAPVFTMPMKDIRVAE-NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            ++T+ P F   ++  ++ +   ++  E ++   G P++RV W RN   + AS++      
Sbjct: 2083 LVTEPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFI 2140

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
                 + M  ++ EDSG + C A N  G    S+ + V+
Sbjct: 2141 DSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 2179



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P  + E  G   V  G+T   EC+V     P L +E+Y +GK L S+ +   +F     S
Sbjct: 2368 PAVIVEKAGPMTVTVGETCTLECKVAGT--PELSVEWYKDGKLLTSSQKHKFSFYNKISS 2425

Query: 2302 LDIQHCVPEDAGEYSVKAINALG--HCTSAISMT 2333
            L I     +DAG Y+ +  N +G   CT+ + ++
Sbjct: 2426 LRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVS 2459



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 3/146 (2%)

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE 1858
            T F  +  +LQL S   S +     +  +          + V + P F+ +   P ++  
Sbjct: 2513 TTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE-PLEVLP 2571

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G++  +   I   P    +V W+   + L  G R     +   A L++  +    SGEYT
Sbjct: 2572 GKNVTFTSVIRGTPP--FKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 2629

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIR 1944
            C   NN GQA  + RL V+   + ++
Sbjct: 2630 CVVSNNAGQASCTTRLFVKEPAAFLK 2655



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 3/99 (3%)

Query: 1707 ITQAPVFTMPMKDIRVA-ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + P F   ++  +VA + ++   E ++   G P+++V W RN   +  S +       
Sbjct: 3025 VKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFIN 3082

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
                L +   + EDSG Y C A N +G+A  S+ L V++
Sbjct: 3083 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 3121



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 7/100 (7%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWF--HNGRPFATGSRVHTLNDFG 3751
            PP F +E  ++++   G P    C+V+  G P +RI W+  H     A   ++   N+  
Sbjct: 3684 PPYF-IEPLEHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVA 3740

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791
              +L I+ +   D GEY+C+A N  G+  ++A +   A++
Sbjct: 3741 --SLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK 3778



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 3/99 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  Q++DV + V G    F+   +   +P + V W+ +GK L      +T       
Sbjct: 4721 PPSFSRQLRDVQETV-GLPVVFDCA-ISGSEP-ISVSWYKDGKPLKDSPNVQTSFLDNTA 4777

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379
             L+I       +G+Y C ATN +G  S+ A L  T  +N
Sbjct: 4778 TLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN 4816



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 16/145 (11%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+   + +E S +           L +   +  D G Y        G    S KL  +
Sbjct: 5353 LSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIASAKLTVI 5408

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV-VPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            +      P +  H+Q++  LK+GQ+    CT+ V    P++K EW+ NG+ ++   R KT
Sbjct: 5409 E------PAWERHLQDVT-LKEGQT----CTMTVQFSVPNVKSEWFRNGRILKPQGRHKT 5457

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCR 3225
              +     L IA  +  D G+Y C+
Sbjct: 5458 EVEHKVHKLTIADVRAEDQGQYTCK 5482



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 633 VYPPPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
           V  PP F+  +  S   + G       +++  G P +++ W KN + +  S+     F  
Sbjct: 398 VREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVN 455

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATG 718
               LD+  + ++DSG Y+C AV+  G
Sbjct: 456 SEAILDITDVKVEDSGSYSCEAVNDVG 482



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 2/83 (2%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F++ +     +  G +A    +L     P ++V W+K+ + ++ S+ +   F      
Sbjct: 402 PSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 459

Query: 830 LNIMHLRAEDAGSYTVRAVNKLG 852
           L+I  ++ ED+GSY+  AVN +G
Sbjct: 460 LDITDVKVEDSGSYSCEAVNDVG 482



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 2/87 (2%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V +   F+ +L     L +G +    C++   P   +++ W+ N + ++   ++R S   
Sbjct: 960  VKEPATFVEKLEPSQLLKKGDATQLACKVTGTPP--IKITWFANDREIKESSKHRMSFVE 1017

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLG 1926
              A L +  V  EDSGEY C+A N  G
Sbjct: 1018 STAVLRLTDVGIEDSGEYMCEAQNEAG 1044



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 4/83 (4%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
            +G    L C++   G   +++ WF N + IK   + R ++      L L  V  EDSG Y
Sbjct: 978  KGDATQLACKV--TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEY 1035

Query: 1384 TCQATNQLGEAVTSCALRVIAKK 1406
             C+A N+ G     C+  VI K+
Sbjct: 1036 MCEAQNEAGS--DHCSSIVIVKE 1056



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 2/104 (1%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP FT     +   + S    EC  I      + ++WF + + +    + K         
Sbjct: 1339 PPSFTKKLKKMDSIKGSFIDLEC--IVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
            LEI  +   D+G YTC ATN+ G    S  L VK     + +PQ
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 1440



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/117 (27%), Positives = 45/117 (38%), Gaps = 3/117 (2%)

Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228
            IE   K  P F++ L  P  V +  ++ LEC  E  G P   V W  N R +    ++  
Sbjct: 1612 IELKVKEPPTFIRELK-PVEVVKYSDVELEC--EVTGTPPFEVTWLKNNREIRSSKKYTL 1668

Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAI 1285
                    L I     +DTGEY     N  GS   S  V + E    +   +N   +
Sbjct: 1669 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTV 1725



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 2/114 (1%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F   +K + V +      E  +   G P   V WL+N   I +S + T      
Sbjct: 1616 VKEPPTFIRELKPVEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTDRVS 1673

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
               L++   +P D+G Y C   NE G    S+ + ++   S   + ++ + + K
Sbjct: 1674 VFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLK 1727



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L  +   +  ++  EC V  +  P  ++ W  NN+ + S  +Y  T   S  +L I
Sbjct: 1622 FIRELKPVEVVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHI 1679

Query: 2836 THTYEEDSGIYTCKATNSKGSATTS 2860
            T     D+G Y C  +N  GS + S
Sbjct: 1680 TKCDPSDTGEYQCIVSNEGGSCSCS 1704



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I K  PVF    S PP V   KN  +    E  G P   V W+ + R +    ++K    
Sbjct: 2177 IVKEPPVFS---SFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASK 2233

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
                ++ I++  ++D GEY  +A N +GS      V++ E
Sbjct: 2234 NFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE 2273



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 2/125 (1%)

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQG 2957
            G R ++      +P  I+  A    +  G+   LE +V     P+L +EWY +GK+L   
Sbjct: 2355 GMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVA--GTPELSVEWYKDGKLLTSS 2412

Query: 2958 SRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK 3017
             + K +      +L ++ V  +D+G YT +  N  G++  ++ V  + +      T+  K
Sbjct: 2413 QKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLK 2472

Query: 3018 GTEGL 3022
             T G+
Sbjct: 2473 NTGGV 2477



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP F+ + + + +++ G++  F +  V    P  KV WF   ++L  G R   + +  +
Sbjct: 2556 EPPSFVKEPEPL-EVLPGKNVTFTS--VIRGTPPFKVNWFRGARELVKGDRCNIYFEDTV 2612

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L++       SGEY CV +N  G+ S    L
Sbjct: 2613 AELELFNIDISQSGEYTCVVSNNAGQASCTTRL 2645



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 5/115 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P F   ++ +  A   +   + ++   G P++ V W +    +  +    T       
Sbjct: 2742 EPPYFVTELEPLEAAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTNNVA 2799

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQ 1823
             L    VN  DSG YTC+A N +G A + +   +Q +   QL       L+ I+Q
Sbjct: 2800 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER---QLPPSFARQLKDIEQ 2851



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 2/89 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++ L  +    GD++  +C V  +  P + + W+  +  L     Y++    +  +L  
Sbjct: 2746 FVTELEPLEAAVGDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYFTNNVATLVF 2803

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLR 2864
                  DSG YTCKA NS G+A++    R
Sbjct: 2804 NKVNINDSGEYTCKAENSIGTASSKTVFR 2832



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 3/114 (2%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V   P F  +P  +   ++G  V  +C++        +V W K+ + V    +F+    
Sbjct: 3118 TVKAPPVFTQKPSPV-GALKGSDVILQCEISGTPP--FEVVWVKDRKQVRNSKKFKITSK 3174

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGL 1552
                 L I++L A D G Y C+A N VG+D  SC +  +     V+   + + L
Sbjct: 3175 HFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTL 3228



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1864 YECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923
            +ECRI    +P ++V WY +G +L+     +TS     A L IL       G+Y C A N
Sbjct: 3800 FECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASN 3857

Query: 1924 NLGQAVSSIRLNVQSKE 1940
             LG A SS +L +   E
Sbjct: 3858 PLGTASSSAKLILSEHE 3874



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 2/95 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++ L     V + +    EC++   G P ++V W+ +   +   S+F+  +      
Sbjct: 3970 PRFIKKLEPSRIVKQDEFTRYECKIG--GSPEIKVLWYKDETEIQESSKFRMSFVDSVAV 4027

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            L++ + +  D+G+YT  A N  GSA +S  ++V E
Sbjct: 4028 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE 4062



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P F +    ++ + GTNV     ++  G     V WF     +  G R   + E
Sbjct: 4434 LTVREPPSFVQKPDPMDVLTGTNVTFTSIVK--GTPPFSVSWFKGSSELVPGDRCNVSLE 4491

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                 L+L  V    SG YTC  +N+ G+A  SC   +  K
Sbjct: 4492 DSVAELELFDVDTSQSGEYTCIVSNEAGKA--SCTTHLYIK 4530



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 38/133 (28%), Positives = 62/133 (46%), Gaps = 12/133 (9%)

Query: 3553 ESGNPPEFTT--TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN 3610
            E  NPP F     P D ++ E  SA FEC +       ++V W  + + + +G + +   
Sbjct: 4813 EGKNPPFFDIRLAPVDAVVGE--SADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISY 4868

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTE 3670
                  L +  V + D+G YTC A N  G+ + + +L +K R    L P  PS  K  +E
Sbjct: 4869 LENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER----LIP--PSFTKRLSE 4922

Query: 3671 SIQKLEETLHKRE 3683
            ++++ E    K E
Sbjct: 4923 TVEETEGNSFKLE 4935



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 3/105 (2%)

Query: 1311 PQFSRAL-HNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            P F++ L   +E  EG +  LE R+   G Q + V W+ N   I+        ++ + + 
Sbjct: 4914 PSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 4971

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
            L +      D+G+YTC+ +N  G A+ + ++ +   K   +  QH
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH 5016



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P FI  L+ V +    K+H E +++   D  + + W K+GQ +     +   F     +L
Sbjct: 309 PHFIKELEPVQSAINKKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 366

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           ++    ++DSG Y C A +  G +   A + V
Sbjct: 367 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 398



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 2/92 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  ++  +  +  G      C+++  G P +++ WF N +  +  + V         
Sbjct: 401  PPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSEA 458

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             LDI  +   D+G Y+C A N  GS + + +I
Sbjct: 459  ILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 490



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 3/102 (2%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F   LR    V  G T   +C++       +R+ ++ +GK + ++ R+ I F  G  S
Sbjct: 778  PFFTKPLRNVDSVVNG-TCRLDCKI--AGSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISE 2343
            L+I      DAG ++ +A N++G   S+ ++ V    S +++
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTK 876



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 3/98 (3%)

Query: 1707 ITQAPVFTMPMKDIRVAEN-QAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + P F      + V  N Q+  FE ++   G PK+RV W  +G  I A  +       
Sbjct: 1522 VKEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFID 1579

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            G     +     E+SGTY C A N+ G A  S  L V+
Sbjct: 1580 GLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 1617



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 3/103 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP F+ EL+    V +      EC+V     P   + +  N + ++S+ ++ +T      
Sbjct: 1619 PPTFIRELK-PVEVVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTLTDRVSVF 1675

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISE 2343
            +L I  C P D GEY     N  G C+ +  + +    S I +
Sbjct: 1676 NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKK 1718



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L  +D +  G + H +C++   G   +  +WF++ K I  S++         VS
Sbjct: 1902 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            + ++++  ED   Y C+ SN+ G+
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAGD 1982



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 2/99 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V + P F   L++   +  G    LE ++     P +++ WF+N   L    + + TF  
Sbjct: 2084 VTEPPKFVKKLEASKIVKAGDSSRLECKIAG--SPEIRVVWFRNEHELPASDKYRMTFID 2141

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             +  + +N+L  +DSG + C+A N  G    +  + +++
Sbjct: 2142 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE 2180



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 2/100 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  P   +     +T   G     E ++   G P + +EW K+G+ + +S +    F   
Sbjct: 2365 VLEPAVIVEKAGPMTVTVGETCTLECKV--AGTPELSVEWYKDGKLLTSSQKHKFSFYNK 2422

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
              SL +LS+  QD+G YT +  +  G +   AV+ V+ RA
Sbjct: 2423 ISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA 2462



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 3/98 (3%)

Query: 2104 QPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD 2163
            +P + P F     S++ +  G+ A FEC V       +T  W  + ++IR G  Y  T  
Sbjct: 2931 EPKKSPFFDIKPVSIDVIA-GESADFECHVTGAQPMRIT--WSKDNKEIRPGGNYTITCV 2987

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 L IL     DSG Y C+ATN +G+ + +  L V
Sbjct: 2988 GNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 3025



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 3/104 (2%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F  +P SI+ VI G+   FEC +       +++ W K+ + +  G  +          
Sbjct: 2936 PFFDIKPVSID-VIAGESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPH 2992

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
            L I+ +   DSG YTC+A N VG D  S +L+ +     V+  +
Sbjct: 2993 LRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLE 3036



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P+F      IE L+ G + H E  L  T  P   V WY + + L++G +++   +     
Sbjct: 4064 PIFRKKPHPIETLK-GADVHLECELQGT--PPFHVSWYKDKRELRSGKKYKIMSENFLTS 4120

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            + I      D GEY C+A N+ G      S+ ++
Sbjct: 4121 IHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 4154



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 781  ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
            E  +G + H E +L     P   V WYKD R + +  +   +      S++I+++ A D 
Sbjct: 4074 ETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADI 4131

Query: 841  GSYTVRAVNKLGEAISTASIRVAA 864
            G Y  +A N +G      SI + A
Sbjct: 4132 GEYQCKATNDVGSDTCVGSIALKA 4155



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN-GKPIKTGHRFRPAY 1363
            I +   P+F + L +I TV G  V L+  ++  G + + V WF + G+ ++       +Y
Sbjct: 4151 IALKAPPRFVKKLSDISTVVGKEVQLQTTIE--GAEPISVVWFKDKGEIVRESDNIWISY 4208

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409
              +   L    V P ++G YTCQ  N  G       L V+    ++
Sbjct: 4209 SENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV 4254



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            + + P F   L+   K+  G    L+ Q+     P + + W+K    L      K  F  
Sbjct: 4622 ILEPPYFVKQLEPV-KVSVGDSASLQCQLAGT--PEIGVSWYKGDTKLRPTTTYKMHFRN 4678

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             + TL  N +  +DSG Y CKA N +GE  ++  + ++++
Sbjct: 4679 NVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 4718



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 1/104 (0%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P FT  + +  V E +   F+      G   + V W +N + I+ ++          + L
Sbjct: 4914 PSFTKRLSET-VEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVL 4972

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814
             ++     D+G YTC+  N+ G A+ +S++ ++      +  QH
Sbjct: 4973 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH 5016



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 3/89 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            ++P + PVF   LT +  + EG+     C V+  ++P + I W   G++I+   R   + 
Sbjct: 5005 KEPKKPPVFDQHLTPV-TVSEGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSF 5061

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLG 2191
              G   L++      DSG Y+CKA+N  G
Sbjct: 5062 ASGTAVLELRDVAKADSGDYVCKASNVAG 5090



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 20/70 (28%), Positives = 36/70 (51%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P ++V W +N   +  SN +          L++  V  EDSG+Y+C A+N++G    S
Sbjct: 428  GSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCS 487

Query: 1798 STLFVQSKAS 1807
            + + ++   S
Sbjct: 488  TEIVIKEPPS 497



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/63 (38%), Positives = 32/63 (50%)

Query: 2798 EPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSA 2857
            E +  P  +I WF +N  L SG +YK+      VSL I      D+G Y C+ TN  GS+
Sbjct: 1080 EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 1139

Query: 2858 TTS 2860
              S
Sbjct: 1140 ICS 1142



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/110 (23%), Positives = 57/110 (51%), Gaps = 3/110 (2%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096
            V + + P F+  ++ T+ +  G +A F+A ++    L +TV W  +  +IT  + I+   
Sbjct: 1145 VTLREPPSFIKKIESTSSL-RGGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTF 1201

Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSI 1146
            +    +L ++ +  +  G Y   A+N AG  + SA ++V+  ++I   ++
Sbjct: 1202 ENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAV 1251



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 38/147 (25%), Positives = 66/147 (44%), Gaps = 15/147 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GF 3752
            PP+F  +    + +  G    F+C++   G P +R+ W+ +G    T  + H ++   G 
Sbjct: 1525 PPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEI-TAIQKHGISFIDGL 1581

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
                I      ++G Y C A N  G+A      +CS    I L+ + P     E +K +E
Sbjct: 1582 ATFQISGARVENSGTYVCEARNDAGTA------SCS----IELKVKEPPTFIRE-LKPVE 1630

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSH 3839
              + SD   E  +  TPP  +T +K++
Sbjct: 1631 VVKYSDVELECEVTGTPPFEVTWLKNN 1657



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/122 (21%), Positives = 61/122 (50%), Gaps = 4/122 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P FT  L+ ++ +  G + H E +++ +    +  +W+ +GK +   +++R  C    V 
Sbjct: 1902 PSFTKKLTKMDKVL-GSSIHMECKVSGSLP--ISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGM-EGTIDKIAAL 3538
            LE++    ED+  Y C+  N  G+   +  + V+   + +++    + + + T++  A L
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAIL 2018

Query: 3539 EG 3540
            +G
Sbjct: 2019 KG 2020



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   LT ++ +  G   H EC+V       ++  WF +G++I    +YR       V+
Sbjct: 1902 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 2169 LDILYTYAEDSGTYMCKATNKLGE 2192
            L++     ED+  Y CK +N  G+
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAGD 1982



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP FT    +      +S   EC++     S + V WFH    +++G++ +T        
Sbjct: 2464 PPSFTRRLKNTGGVLGASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCT 2521

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
            L++  +   D G YTC A N  G       L V+     + EP+
Sbjct: 2522 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 2565



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 37/143 (25%), Positives = 63/143 (44%), Gaps = 6/143 (4%)

Query: 1663 TSGIAIVHSKKSIYLESQHEG--ALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDI 1720
            TS +  V + K +  +  H G  +    N L   S   R +A++    ++P F +    I
Sbjct: 2888 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREP--KKSPFFDIKPVSI 2945

Query: 1721 RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDS 1780
             V   ++A FE  +   G   +R+ W ++   I      T         L +  V   DS
Sbjct: 2946 DVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDS 3003

Query: 1781 GTYTCRAINELGEAVTSSTLFVQ 1803
            G YTC+A N++G+ + S+ L V+
Sbjct: 3004 GQYTCQATNDVGKDMCSAQLSVK 3026



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 2/86 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F      V A++G  +  +  I   G P  ++ W+K+ + +  S +F    +  
Sbjct: 3119 VKAPPVFTQKPSPVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHF 3176

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATG 718
              +L +L+L   D GEY C+A +  G
Sbjct: 3177 DTNLHILNLEASDVGEYHCKATNEVG 3202



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 2/97 (2%)

Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            FV E   F K + +  V  G P+ LEAT T    P + V W  +   + Q  R   T   
Sbjct: 3587 FVKEPATFVKRLADFSVETGSPIVLEATYT--GTPPISVSWIKDEYLISQSERCSITMTE 3644

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L+IL +  ED   Y C   N  G+ +  + V V
Sbjct: 3645 KSTILEILESTIEDYAQYSCLIENEAGQDICEALVSV 3681



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  +++DV + + G    FE R +   +P L+V W+ +G  L      +T     + 
Sbjct: 3780 PPFFARKLKDVHETL-GFPVAFECR-INGSEP-LQVSWYKDGVLLKDDANLQTSFVHNVA 3836

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
             L IL   + + G+Y C A+N LG  S+ A L  +  E
Sbjct: 3837 TLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 3874



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 5/103 (4%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            SV      V +P+SI+ V  G     EC +    +  L  +WFK+G+ +T  ++++ I  
Sbjct: 4246 SVLEPATIVEKPESIK-VTTGDTCTLECTVAGTPE--LSTKWFKDGKELTSDNKYK-ISF 4301

Query: 1499 FGYVA-LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540
            F  V+ L II++   DSG+Y+    N VG D  +  L     T
Sbjct: 4302 FNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT 4344



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 2/75 (2%)

Query: 793  QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS-LNIMHLRAEDAGSYTVRAVNKL 851
            + T    P +  +W+KDG+ +T+ ++    F F  VS L I+++   D+G Y+    N +
Sbjct: 4271 ECTVAGTPELSTKWFKDGKELTSDNKYKISF-FNKVSGLKIINVAPSDSGVYSFEVQNPV 4329

Query: 852  GEAISTASIRVAARS 866
            G+   TAS++V+ R+
Sbjct: 4330 GKDSCTASLQVSDRT 4344



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 2/100 (2%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P FT  +K+       +   E ++   G P + V W   G  I +  +  T      
Sbjct: 4344 TVPPSFTRKLKETNGLSGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNT 4401

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
             AL +  +   DSG YTC A N  G    S+ L V+   S
Sbjct: 4402 CALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPS 4441



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +K      G  V +E  +     P + V W+  G  +  G +++TT      AL
Sbjct: 4347 PSFTRKLKETNGLSGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTCAL 4404

Query: 2038 DILYAYAEDTGTYMCKATNAVG 2059
             +      D+G Y C ATN  G
Sbjct: 4405 TVNMLEESDSGDYTCIATNMAG 4426



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 2/102 (1%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I +++ P F + L  ++   G +  L+C+L   G   + V W+     ++    ++  + 
Sbjct: 4620 ILILEPPYFVKQLEPVKVSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRPTTTYKMHFR 4677

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
             +   L    V   DSG Y C+A N +GE   S  L V  +K
Sbjct: 4678 NNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK 4719



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 3/100 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++    G  + F+C +  S +P + + W+ + KPL      +++   +  +L+I
Sbjct: 4724 FSRQLRDVQETVGLPVVFDCAISGS-EP-ISVSWYKDGKPLKDSPNVQTSFLDNTATLNI 4781

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKN-IYFD 2874
              T    +G Y+C ATN  GSA++S  L  T  KN  +FD
Sbjct: 4782 FKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFD 4821



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 3/115 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F  ++ S TVEE+EG  F+          + + WY+N   +         +    + 
Sbjct: 4913 PPSFTKRL-SETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 4971

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK--KLPDIILQNQVPRGMKRSE 3941
            L +      D+G Y C+  ND G     ++I  K  K P +  Q+  P  +   E
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGE 5026



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 21/68 (30%), Positives = 30/68 (44%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E  G     + W KD   + +  +  TF     V+L I      DAG Y CR  N +G +
Sbjct: 1080 EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 1139

Query: 994  TTSANLTI 1001
              SA +T+
Sbjct: 1140 ICSARVTL 1147



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 21/66 (31%), Positives = 34/66 (51%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L+V+WLKDG+ +  S   +  F     +  I+SV   D+G YT +  N  G ++  
Sbjct: 1831 GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCD 1890

Query: 997  ANLTIV 1002
            A L ++
Sbjct: 1891 AYLRVL 1896



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 2/78 (2%)

Query: 924  GGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYT 983
            G   H E ++   G   +  +W KDG+ +  S++     +   V+L + ++ + D  +YT
Sbjct: 1916 GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYT 1973

Query: 984  CRAYNAIGQATTSANLTI 1001
            C+  N  G    S  LT+
Sbjct: 1974 CKVSNVAGDDACSGILTV 1991



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            VT  P+FV + ++ + V  G     ECK+       ++V WF+N   +    ++R     
Sbjct: 2084 VTEPPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFID 2141

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                + + +L  EDSG + C A N  G+   S ++
Sbjct: 2142 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV 2176



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+F  +++ +  V  G     +C++   G P +R+ WF N        +          
Sbjct: 2087 PPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 2144

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + ++ +   D+G++ C A N  GS + + K+
Sbjct: 2145 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKV 2176



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 2/102 (1%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F  ++K+           EC+V       + + W+     + SG +Y+T +    
Sbjct: 2462 AVPPSFTRRLKNTGGVLGASCILECKVAGSSP--ISVAWFHEKTKIVSGAKYQTTFSDNV 2519

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
             +L +  + + D G Y C A N  G D  +A ++ ++ P  +
Sbjct: 2520 CTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFV 2561



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  E  + ++V  G  V F   +   G P  +++WF   R    G R +   +    
Sbjct: 2557 PPSFVKE-PEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDTVA 2613

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             L++  I    +GEYTC  +N  G A+ T ++
Sbjct: 2614 ELELFNIDISQSGEYTCVVSNNAGQASCTTRL 2645



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L  +E    G++   + ++  T  P + V WY     L+    +RT+       
Sbjct: 2744 PYFVTELEPLE-AAVGDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYFTNNVAT 2800

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
            L  +     DSGEY C+A N+ G A +    ++Q ++
Sbjct: 2801 LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ 2837



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 4/95 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +K+ E T G PV L   L       ++V WY +G  ++     +T++      L
Sbjct: 2840 PSFARQLKDIEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDHENLQTSFVDNVATL 2897

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             IL      +G Y C A+N +G A  +SS ++ A+
Sbjct: 2898 KILQTDLSHSGQYSCSASNPLGTA--SSSARLTAR 2930



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/109 (22%), Positives = 50/109 (45%), Gaps = 2/109 (1%)

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
            S +    + P+F++ L+     ++G +   E +++    P ++V W+++   +  S +  
Sbjct: 3020 SAQLSVKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYN 3077

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVT 869
              F      L I    AED+G Y   A N +G+A  + ++ V A    T
Sbjct: 3078 MSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFT 3126



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP FI +++DV  ++ G S   E R+       + V WF +G ++  G + ++     + 
Sbjct: 3405 PPSFIRKLKDVNAIL-GASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVC 3461

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             L++      ++G Y CVA N  G D   A L
Sbjct: 3462 TLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 3493



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L ++    G ++  EC V  S    + + WF +   + SG + +S+   +  +L++
Sbjct: 3408 FIRKLKDVNAILGASVVLECRVSGSAP--ISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 3465

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            +     D+GIYTC A N  GS   S  L
Sbjct: 3466 SLLEPSDTGIYTCVAANVAGSDECSAVL 3493



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E PIF +    P E  +G   H E  +   G P     WY +  EL+ G +++   +   
Sbjct: 4062 EPPIFRKK-PHPIETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFL 4118

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             ++ I +V A D G Y CKA N  G
Sbjct: 4119 TSIHILNVDAADIGEYQCKATNDVG 4143



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 23/85 (27%), Positives = 44/85 (51%), Gaps = 2/85 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V+ G    LEC +   G P +  +WF +G+ +T  +++K  +      L II+   +D+G
Sbjct: 4262 VTTGDTCTLECTVA--GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSG 4319

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERS 1273
             Y+    N +G    +A ++V +R+
Sbjct: 4320 VYSFEVQNPVGKDSCTASLQVSDRT 4344



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 3/100 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V + T  P F   +K+   +  G     E ++   G   + V W  +G  + +  +  T 
Sbjct: 4340 VSDRTVPPSFTRKLKETNGLS-GSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTT 4396

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                  ALT+  +   D+G YTC A N  G    SA LT+
Sbjct: 4397 LTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 4436



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L   D +V G+    E  V   T P +K+ W K+   + +G + + ++      
Sbjct: 4818 PFFDIRLAPVDAVV-GESADFECHVTG-TQP-IKVSWAKDSREIRSGGKYQISYLENSAH 4874

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            L++  +   DSG YTC A N +G+   TA + I++R
Sbjct: 4875 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 4910



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F  R   ++ V+ G+   FEC +       +KV W K+ + +  G +++  +      
Sbjct: 4818 PFFDIRLAPVDAVV-GESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLENSAH 4874

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            L ++ +   DSG YTC AVN VG D  + +L  +
Sbjct: 4875 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIK 4908



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984
            EG+ + L   V+  ++P ++I+W   G+ ++   R   +   G   L+L DV + DSG Y
Sbjct: 5024 EGEYVQLSCHVQG-SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDY 5081

Query: 2985 TCKAYNKRGEAFTSSTVYCTSKDNLIERTQ 3014
             CKA N  G   T S V    K  +   T+
Sbjct: 5082 VCKASNVAGSDTTKSKVTIKDKPAVAPATK 5111



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 50/210 (23%), Positives = 85/210 (40%), Gaps = 30/210 (14%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GY 4030
            PP  +T +Q  T   E +  +F+C+   V   ++KV W+   K +   +RF  +  F   
Sbjct: 9    PPAIITPLQD-TVTSEGQPARFQCR---VSGTDLKVSWYSKDKKI-KPSRFFRMTQFEDT 63

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREM 4090
              +     YPED G Y   A N  G   + A +       I+++         IE  +E+
Sbjct: 64   YQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHE--------RIE--QEI 113

Query: 4091 EASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT 4150
            E   +  P  V+   K +  P+ V+L        G  A+F C +   P  R  W   G  
Sbjct: 114  EMEMKAAP--VI---KRKIEPLEVAL--------GHLAKFTCEIQSAPNVRFQWFKAGRE 160

Query: 4151 IVNGSRYKL-TYDGMYHFDIPKTRQYDTGK 4179
            I    +  + +   +   +I +T+  D G+
Sbjct: 161  IYESDKCSIRSSKYISSLEILRTQVVDCGE 190



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 2/101 (1%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP FV ++  +  +  G++A   C+++    P +++ ++ N K L  +    + F     
Sbjct: 401  PPSFVKKVDPSYLMLPGESARLHCKLKG--SPVIQVTWFKNNKELSESNTVRMYFVNSEA 458

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSII 2341
             LDI     ED+G YS +A+N +G  + +  + +    S I
Sbjct: 459  ILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFI 499



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 2/100 (2%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            +S  +P  +   +    V++G    L+ +    G   +  +WF +G+ +T+GS++K    
Sbjct: 1238 LSVKEPATITEEAVSIDVTQGDPATLQVKFS--GTKEITAKWFKDGQELTLGSKYKISVT 1295

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
                 L II     D+GEYT    N +G +   A + V++
Sbjct: 1296 DTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLD 1335



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 20/61 (32%), Positives = 34/61 (55%)

Query: 2141 LTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
            +TI WF + +++ +G       D    +L++    A DSGTY+C+ +N +G A +  TL 
Sbjct: 1462 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 1521

Query: 2201 V 2201
            V
Sbjct: 1522 V 1522



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/94 (23%), Positives = 42/94 (44%), Gaps = 2/94 (2%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            Q P  + +      + E +    EC +A  G P +KV+W  +GK ++    F+  ++   
Sbjct: 1803 QEPAQIVEKAKSVDVTEKDPMTLECVVA--GTPELKVKWLKDGKQIVPSRYFSMSFENNV 1860

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064
             +     V  +DSG+Y  +  N +G     A ++
Sbjct: 1861 ASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLR 1894



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 20/63 (31%), Positives = 31/63 (49%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P ++V+W KDG+ I  S   +  F     S  I  +  +D+G YT +  N  G +   A 
Sbjct: 1833 PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 1892

Query: 860  IRV 862
            +RV
Sbjct: 1893 LRV 1895



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 2/109 (1%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P  T  L  ++   G   H E ++       +  +W+ + K + + +++    +   V+L
Sbjct: 1902 PSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSL 1959

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALP 1686
            ++ +   ED+  YTC+  N  G+   SGI  V    S  ++   + A+P
Sbjct: 1960 EVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIP 2008



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F + L     +  G  +  E ++   G P +R  W+ N  EL    ++R T     
Sbjct: 2086 EPPKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDSV 2143

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
              + +N++   D+G ++C+A N AG
Sbjct: 2144 AVIQMNNLSTEDSGDFICEAQNPAG 2168



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FV+    P  V  GKN+     +   G P  +V WF   R +  G R   Y++     
Sbjct: 2558 PSFVKE-PEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 2614

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSA 1261
            L++ +   + +GEYT    N+ G A
Sbjct: 2615 LELFNIDISQSGEYTCVVSNNAGQA 2639



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 2/91 (2%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P+++  + A     +G+ + LE ++     P++K+ W+ N   L +  ++ ++       
Sbjct: 3029 PKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSVAL 3086

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            L + +    DSG Y C+A+N  G+A  S+ +
Sbjct: 3087 LTINEASAEDSGDYICEAHNGVGDASCSTAL 3117



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/111 (24%), Positives = 45/111 (40%), Gaps = 2/111 (1%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP   TQ   P    +G     +C I   P     V W  + K +++  +++ ++    
Sbjct: 3120 KAPPVFTQKPSPVGALKGSDVILQCEISGTPP--FEVVWVKDRKQVRNSKKFKITSKHFD 3177

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952
              L IL +   D GEY CKA N +G    S  +  +     ++     S L
Sbjct: 3178 TNLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTL 3228



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 2/91 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   LK V    G  + FE RI   G   +++ W K+G  ++  +   + F     +
Sbjct: 3780 PPFFARKLKDVHETLGFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHNVAT 3837

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVL 726
            L +L  +    G+Y C A +  G A + A L
Sbjct: 3838 LQILQTDQSHIGQYNCSASNPLGTASSSAKL 3868



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F   +KD +    G    FE R+   G   L+V W KDG  ++  + + T F      
Sbjct: 3781 PFFARKLKD-VHETLGFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHNVAT 3837

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I        G Y C A N +G A++SA L +
Sbjct: 3838 LQILQTDQSHIGQYNCSASNPLGTASSSAKLIL 3870



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 21/86 (24%), Positives = 45/86 (52%), Gaps = 2/86 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F + L+    +++ +   ++C++   G P +KV W+++E  I++SS+   +    
Sbjct: 3967 QEPPRFIKKLEPSRIVKQDEFTRYECKI--GGSPEIKVLWYKDETEIQESSKFRMSFVDS 4024

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
               + + ++  ED G Y C A N  G
Sbjct: 4025 VAVLEMHNLSVEDSGDYTCEAHNAAG 4050



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            K+  G +   E  V    +L+   +W+ +GK++TS N+ +         L I +V   DS
Sbjct: 4261 KVTTGDTCTLECTVAGTPELS--TKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDS 4318

Query: 1114 GVYTVVARNAAGEAQLSASMTVETRS 1139
            GVY+   +N  G+   +AS+ V  R+
Sbjct: 4319 GVYSFEVQNPVGKDSCTASLQVSDRT 4344



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            +P +     + + +  G  A  + +L   G   + V W K    +  ++     F     
Sbjct: 4624 EPPYFVKQLEPVKVSVGDSASLQCQLA--GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVA 4681

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
             L    V ++D+G Y C+A N++G+ + S  LT+  +K
Sbjct: 4682 TLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK 4719



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 5/123 (4%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
            + + QY    +  ET   + I  + +  QF K  Q+  V+E +   F+C V+      VT
Sbjct: 5474 EDQGQYTCKYEDLETSAELRIEAEPI--QFTKRIQNIVVSEHQSATFECEVSFDD-AIVT 5530

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVAR-NKSGETAFQCRLNVI 483
            W+    ++ +   +    N+   H + I NVT  D GV + +AR    GE      L + 
Sbjct: 5531 WYKGPTELTESQKYNFR-NDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLT 5589

Query: 484  EKE 486
             KE
Sbjct: 5590 TKE 5592



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1974 VVEKPQFGKPIKNAE---VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY 2030
            +V++P   K I+ AE   VT G P  LE T+     P ++ +WY +GRP+    +++ ++
Sbjct: 677  IVKEP--AKIIERAELIQVTAGDPATLEYTVA--GTPELKPKWYKDGRPLVASKKYRISF 732

Query: 2031 DFGYVALDILYAYAEDTGTYMCKATNAVGEA 2061
                  L    A   D+G Y  + +N VG +
Sbjct: 733  KNNVAQLKFYSAELHDSGQYTFEISNEVGSS 763



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 2/87 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EP  F+ +++    L +G +     ++     P +K+ WF N +++    ++R       
Sbjct: 962  EPATFVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVEST 1019

Query: 3340 VILDILYCYEENSGEYECVATNKLGRD 3366
             +L +     E+SGEY C A N+ G D
Sbjct: 1020 AVLRLTDVGIEDSGEYMCEAQNEAGSD 1046



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 21/61 (34%), Positives = 33/61 (54%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P +KI W+ N + +++ S+ +++       L L DV   DSG Y C+A N+ G    SS 
Sbjct: 992  PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSI 1051

Query: 3001 V 3001
            V
Sbjct: 1052 V 1052



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 49/281 (17%), Positives = 96/281 (34%), Gaps = 15/281 (5%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            QG  A  + K  G       W +    L   +KY +   +    + ++  +    D GEY
Sbjct: 1257 QGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTE--KKDSGEY 1314

Query: 145  TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET---VEHKAYGTQGYTTEQS 201
            T   +N  G + C   I                    +  +   +E    G+   + +  
Sbjct: 1315 TFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWF 1374

Query: 202  RQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITK-RYVGESDVQIS-TEIDRS 259
            +  Q++        S+++ +K    +     E+S  E      Y   +  +    +    
Sbjct: 1375 KDDQEI--------SASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGH 1426

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            L    PP   +KP++  +      Q +  + G     + WFK+ + L +     +     
Sbjct: 1427 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDT 1486

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             T+L +   + +DSG Y     N  G   +   L V+ P +
Sbjct: 1487 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQ 1527



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 5/96 (5%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP FI +++ V ++V+      E  +     P  +V W  N +++    +Y       +
Sbjct: 1618 EPPTFIRELKPV-EVVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTLTDRVSV 1674

Query: 3340 VILDILYCYEENSGEYECVATNKLG--RDSTKANLK 3373
              L I  C   ++GEY+C+ +N+ G    ST+  LK
Sbjct: 1675 FNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 1710



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            VQ+        KS D + E   + LE  V     P LK++W K+G  +        +F+ 
Sbjct: 1802 VQEPAQIVEKAKSVD-VTEKDPMTLECVVAGT--PELKVKWLKDGKQIVPSRYFSMSFEN 1858

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
             + +  I S+   DSG YT K  N  G +   A +++ D++
Sbjct: 1859 NVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQN 1899



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 3/115 (2%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            Q  P F   LK  ++ V G  V L  ++       +++ W+++GV L     L+++F   
Sbjct: 2837 QLPPSFARQLKDIEQTV-GLPVTLTCRLNGSAP--IQVCWYRDGVLLRDHENLQTSFVDN 2893

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRI 2753
            + TL I       SG Y+C A+N LG A S+A +   +        + P S+D I
Sbjct: 2894 VATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVI 2948



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 2/91 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F +        +G  V L+  ++    P   V W  + + V+   +FK T       L
Sbjct: 3123 PVFTQKPSPVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNL 3180

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
             IL   A D G Y CKATN VG    + SVK
Sbjct: 3181 HILNLEASDVGEYHCKATNEVGSDTCSCSVK 3211



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PVF    + +  LK  D    +C +     P   + W  + +++R   +++ T       
Sbjct: 3123 PVFTQKPSPVGALKGSD-VILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTN 3179

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
            L IL   A D G Y CKATN++G    +C++K
Sbjct: 3180 LHILNLEASDVGEYHCKATNEVGSDTCSCSVK 3211



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 2/90 (2%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF    + +   +G ++  +C +  S  P  ++ W  + K + +  ++K T      +L 
Sbjct: 3124 VFTQKPSPVGALKGSDVILQCEI--SGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLH 3181

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            I +    D G Y CKATN  GS T S S++
Sbjct: 3182 ILNLEASDVGEYHCKATNEVGSDTCSCSVK 3211



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 12/125 (9%)

Query: 750  LEDYSKYQ-------HQESIEEQTS--QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDP 800
            +EDY++Y         Q+  E   S  + P FI PL+ + E   G  A  + ++     P
Sbjct: 3656 IEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHV-EAVIGEPATLQCKVD--GTP 3712

Query: 801  TMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
             +R+ WYK+   + ++      F     SL I  +   D G Y+ +A N +G   S+A +
Sbjct: 3713 EIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVL 3772

Query: 861  RVAAR 865
             + AR
Sbjct: 3773 VIKAR 3777



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L  +E +  G+ A  +C+V+    P + I W+    K+R+   Y+        +
Sbjct: 3685 PYFIEPLEHVEAVI-GEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVAS 3741

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR 2205
            L I      D G Y CKA N +G   ++  L +   +
Sbjct: 3742 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK 3778



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 3/98 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ PIF       + L +G  V+LE +++    P   + W+K+   L +G + K   + 
Sbjct: 4060 VKEPPIFRKKPHPIETL-KGADVHLECELQGT--PPFHVSWYKDKRELRSGKKYKIMSEN 4116

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             L ++ I ++   D G Y CKATN +G      SI ++
Sbjct: 4117 FLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 4154



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 3/99 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K+ P F   L+ P     G++   EC +   G   ++V W  + R +  G +++  Y   
Sbjct: 4815 KNPPFFDIRLA-PVDAVVGESADFECHVT--GTQPIKVSWAKDSREIRSGGKYQISYLEN 4871

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
               L ++     D+G+YT  AVN +G    +A + + ER
Sbjct: 4872 SAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 4910



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 666 PTMKIEWLKNGQSIEASSRFTSIFRFGYIS-LDMLSLNIQDSGEYTCRAVSATGVAETKA 724
           P ++ +W K G+ I  S +  SI    YIS L++L   + D GEYTC+A +  G     A
Sbjct: 148 PNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 206

Query: 725 VLHVT 729
            L VT
Sbjct: 207 TLTVT 211



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/99 (24%), Positives = 48/99 (48%), Gaps = 2/99 (2%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F   +     ++ G+   L  ++  +  P +++ WFKN   L+    ++  F  
Sbjct: 398  VREPPSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVN 455

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                L I  ++ +DSG Y+C+A N +G    +  I I++
Sbjct: 456  SEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE 494



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/121 (21%), Positives = 52/121 (42%), Gaps = 2/121 (1%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P ++  +   + ++ G+   L  ++  K  P +++ W+ N K L + +  ++        
Sbjct: 402  PSFVKKVDPSYLMLPGESARLHCKL--KGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 459

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLED 3030
            LD+ DV   DSG Y+C+A N  G    S+ +      + I+  +      G   +   E 
Sbjct: 460  LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEV 519

Query: 3031 S 3031
            S
Sbjct: 520  S 520



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 4/93 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  +     +  G+ A   C+++    P + + WF N +++   +  R         
Sbjct: 402  PSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 459

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            LDI     EDSG+Y C+A N +G   ++C+ ++
Sbjct: 460  LDITDVKVEDSGSYSCEAVNDVGS--DSCSTEI 490



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L+ +D+I+ G     +C  I  G   + ++WF++++ I  S +   +       
Sbjct: 1340 PSFTKKLKKMDSIK-GSFIDLEC--IVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + IS +   D G Y C A+N  G
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAG 1419



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P F     + +    T V L+  +   G   M ++WF + K + +G   R  ++
Sbjct: 1427 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVG--GTAPMTIKWFKDNKELHSGAA-RSVWK 1483

Query: 1365 FDY-VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             D   +L+L +    DSG Y CQ +N +G A +   L V
Sbjct: 1484 DDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFV 1522



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 21/59 (35%), Positives = 32/59 (54%)

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            + I+WF +NK L SG       D +  SL++      DSG Y C+ +N  G+AT+  +L
Sbjct: 1462 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATL 1520



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/113 (23%), Positives = 50/113 (44%), Gaps = 2/113 (1%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P F++  S    +  G++   EC++   G P +RV W+ +G  +T   +    +  G
Sbjct: 1523 KEPPQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDG 1580

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286
                 I  A   ++G Y   A N  G+A  S  ++V E    + + +  + ++
Sbjct: 1581 LATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVK 1633



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 2/104 (1%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P+F       + ++ G    FE ++   G   +RV W  DG  + A  +    F  G 
Sbjct: 1524 EPPQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGL 1581

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                I    V ++G Y C A N  G A+ S  L +      I E
Sbjct: 1582 ATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE 1625



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F +  +    L  GQ   +E ++   G P +R  WY++G E+    +   +   G 
Sbjct: 1524 EPPQFIKKPSPVLVLRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGL 1581

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             T  I+     ++G Y+C+A N AG
Sbjct: 1582 ATFQISGARVENSGTYVCEARNDAG 1606



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L  +E +K  D    EC V     P   + W  N ++IR+  +Y  T       
Sbjct: 1620 PTFIRELKPVEVVKYSD-VELECEVT--GTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN 1676

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
            L I      D+G Y C  +N+ G    +C+ +VA
Sbjct: 1677 LHITKCDPSDTGEYQCIVSNEGGSC--SCSTRVA 1708



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 3/112 (2%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFG 1900
            N  P F  +L    K+  G S H EC++       +  +W+ +GK + +  +YR      
Sbjct: 1899 NIPPSFTKKLTKMDKVL-GSSIHMECKVSG--SLPISAQWFKDGKEISTSAKYRLVCHER 1955

Query: 1901 FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952
              +L++  +  ED+  YTCK  N  G    S  L V+   S +     + A+
Sbjct: 1956 SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAI 2007



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 5/100 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTE-GHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P+F K ++ +++ + G    LE  +     P +RV W+ N   +    +++ T+  
Sbjct: 2084 VTEPPKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFID 2141

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
                + +     ED+G ++C+A N  G   T+ S KV  K
Sbjct: 2142 SVAVIQMNNLSTEDSGDFICEAQNPAGS--TSCSTKVIVK 2179



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 4/109 (3%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            T+ P+F   ++    +K G  +  E ++   G   +RV W ++   + AS +    F   
Sbjct: 2085 TEPPKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDS 2142

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014
               + + +++  D+G + C A N  G  +TS +  ++ K+  +  S  P
Sbjct: 2143 VAVIQMNNLSTEDSGDFICEAQNPAG--STSCSTKVIVKEPPVFSSFPP 2189



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F       E  +   V LE  L+    P   V WY + R ++   ++K      
Sbjct: 2178 VKEPPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNF 2235

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            + ++ IL     D G Y CKA N VG      +VK+
Sbjct: 2236 HTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL 2271



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 6/138 (4%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            V  K+PPRFV+++ S T +V  E  + +  +   G   + V+W    + ++ ++    I 
Sbjct: 2269 VKLKEPPRFVSKLNSLT-VVAGEPAELQASIE--GAQPIFVQWLKEKEEVIRESENIRIT 2325

Query: 4027 DFGYVA-MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIE 4085
                VA + F    P ++G+Y+C+  N  GM E  A +    +P ++ +   P  + ++ 
Sbjct: 2326 FVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVL-EPAVIVEKAGPMTV-TVG 2383

Query: 4086 KIREMEASWQVTPEQVVE 4103
            +   +E     TPE  VE
Sbjct: 2384 ETCTLECKVAGTPELSVE 2401



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 3/109 (2%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D+  PP F  ++++ T  V   +   EC++A  G   + V WF     ++   ++   + 
Sbjct: 2460 DRAVPPSFTRRLKN-TGGVLGASCILECKVA--GSSPISVAWFHEKTKIVSGAKYQTTFS 2516

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQ 4076
                 +    +   D G Y C A N+ G DE +AV+     P  V + +
Sbjct: 2517 DNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 2565



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F   L  P E   G     + +V   G P +   WY    +L+    +RT      
Sbjct: 2742 EPPYFVTELE-PLEAAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTNNV 2798

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             TL  N V  ND+G Y CKA N  G
Sbjct: 2799 ATLVFNKVNINDSGEYTCKAENSIG 2823



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G++  FEC+V  ++   ++I W  +NK +  G  Y  T   +   L I    + DSG YT
Sbjct: 2950 GESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYT 3007

Query: 2848 CKATNSKGSATTSGSL 2863
            C+ATN  G    S  L
Sbjct: 3008 CQATNDVGKDMCSAQL 3023



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 20/66 (30%), Positives = 35/66 (53%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P L  +WFK+G  L+  ++   TF   + +L I      D G+Y+ +  N +G++  T S
Sbjct: 3337 PELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVS 3396

Query: 2732 IKIEDR 2737
            + + DR
Sbjct: 3397 VHVSDR 3402



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P FIR L+D+  +  G +   E +++  S P + V W++DG  I +  +  S F+    +
Sbjct: 3406 PSFIRKLKDVNAIL-GASVVLECRVSG-SAP-ISVGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            LN+  L   D G YT  A N  G    +A + V
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 3495



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 19/99 (19%), Positives = 47/99 (47%), Gaps = 2/99 (2%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F  P++ +     + A  + ++   G P++R+ W +    + ++          
Sbjct: 3681 VLEPPYFIEPLEHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNN 3738

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
              +L +  V+  D G Y+C+A N +G   +S+ L ++++
Sbjct: 3739 VASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR 3777



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 3/99 (3%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F  P+ + +    G  A  + +++  G   +R+ W K+   + ++      F    
Sbjct: 3683 EPPYFIEPL-EHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNV 3739

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
             +L I  V   D G Y+C+A N++G   +SA L I  +K
Sbjct: 3740 ASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK 3778



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 3/97 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F  PL ++E +  GE A  + ++  T  P +++ WY     L++   ++         
Sbjct: 3685 PYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNNVAS 3741

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
            L I+     D GEY C+A N+ G   ++A + ++ ++
Sbjct: 3742 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK 3778



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 3/91 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F R L+D+ E   G    FE ++   S+P ++V WYKDG  +   + + + F     +
Sbjct: 3781 PFFARKLKDVHETL-GFPVAFECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVAT 3837

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            L I+       G Y   A N LG A S+A +
Sbjct: 3838 LQILQTDQSHIGQYNCSASNPLGTASSSAKL 3868



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +K+   T G PV  E  +   ++P ++V WY +G  ++     +T++      L
Sbjct: 3781 PFFARKLKDVHETLGFPVAFECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVATL 3838

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067
             IL       G Y C A+N +G A +++ +
Sbjct: 3839 QILQTDQSHIGQYNCSASNPLGTASSSAKL 3868



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQ--APRFITQLNGPTKL 1856
            T FV + A+LQ+    +S + +      +         ++ +++   P F         L
Sbjct: 3829 TSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDL 3888

Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGE 1916
            + G+S  ++C +       +++ W  + + ++ G  Y+ +     A L +L V   D+G+
Sbjct: 3889 ALGESGTFKCHVTGTAP--IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQ 3946

Query: 1917 YTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            YTC A N  G+   S +L VQ     I+
Sbjct: 3947 YTCYASNIAGKDSCSAQLGVQEPPRFIK 3974



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 2/107 (1%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+  +T S   P  I +  +  K+  G +   E  +     P+L  +WF +GK+L   ++
Sbjct: 4239 QECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGT--PELSTKWFKDGKELTSDNK 4296

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
            Y+      +  L I+     +SG Y     N +G+DS  A+L+ + +
Sbjct: 4297 YKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 4343



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 6/111 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP F  +L+ T  +  G +   EC+V     P + + ++H G  + S  ++  T      
Sbjct: 4346 PPSFTRKLKETNGL-SGSSVVMECKV--YGSPPISVSWFHEGNEISSGRKYQTTLTDNTC 4402

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
            +L +      D+G+Y+  A N  G    +  +TV    S +   Q+P+ ++
Sbjct: 4403 ALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV---QKPDPMD 4450



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 3265 SLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKK 3324
            ++ G+ + +      EPP F+ Q  D   ++ G +  F +  +    P   V WF    +
Sbjct: 4423 NMAGSDECSAPLTVREPPSFV-QKPDPMDVLTGTNVTFTS--IVKGTPPFSVSWFKGSSE 4479

Query: 3325 LPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            L  G R     +  +  L++       SGEY C+ +N+ G+ S   +L
Sbjct: 4480 LVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHL 4527



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            +PP FV Q++     V  ++   +CQLA  G P + V W+     L     +   +    
Sbjct: 4624 EPPYFVKQLEPVKVSVG-DSASLQCQLA--GTPEIGVSWYKGDTKLRPTTTYKMHFRNNV 4680

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYG 4055
              + F  V   DSGEY+C+A N  G
Sbjct: 4681 ATLVFNQVDINDSGEYICKAENSVG 4705



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FV+ L  P  VS G +  L+C+L   G P + V W+     +   + +K ++      
Sbjct: 4626 PYFVKQLE-PVKVSVGDSASLQCQLA--GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVAT 4682

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            L        D+GEY  +A N +G    S  + V E+
Sbjct: 4683 LVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ 4718



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            E  NPP F + +   +D   G    F+C V   G   +++ W  + R   +G +      
Sbjct: 4813 EGKNPPFFDIRLAP-VDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYL 4869

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                 L +  +   D+G+YTC A N+ G  + TA++
Sbjct: 4870 ENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL 4905



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 2/91 (2%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F + L +  E  EG +   E ++   S P + V WYK+   I  +S     F    + 
Sbjct: 4914 PSFTKRLSETVEETEGNSFKLEGRVAG-SQP-ITVAWYKNNIEIQPTSNCEITFKNNTLV 4971

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            L +      DAG YT +  N  G A+ T+SI
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSI 5002



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 7/84 (8%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491
            L+EG+      + +    PN+K EW+ NG+ LK   R +T  +     L I+    ED G
Sbjct: 5421 LKEGQTCTMTVQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQG 5477

Query: 3492 EYLCRAYNNYGEAVTTASMKVQGK 3515
            +Y C+    Y +  T+A ++++ +
Sbjct: 5478 QYTCK----YEDLETSAELRIEAE 5497



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 1/96 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  P  F+  L+    ++ G    +   +  G P +KI W  N + I+ SS+    F   
Sbjct: 960  VKEPATFVEKLEPSQLLKKGDAT-QLACKVTGTPPIKITWFANDREIKESSKHRMSFVES 1018

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
               L +  + I+DSGEY C A +  G     +++ V
Sbjct: 1019 TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV 1054



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 15/152 (9%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P  F  +++ +  + +G      C+V   G P ++I WF N R     S+ H ++     
Sbjct: 963  PATFVEKLEPSQLLKKGDATQLACKV--TGTPPIKITWFANDREIKESSK-HRMSFVEST 1019

Query: 3754 A-LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
            A L +  +   D+GEY C A N+ GS        CS+   IV+  + P     ++ K +E
Sbjct: 1020 AVLRLTDVGIEDSGEYMCEAQNEAGSD------HCSS---IVIVKESP--YFTKEFKPIE 1068

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEES 3844
              +  D      +  TPP  IT  K +T+  S
Sbjct: 1069 VLKEYDVMLLAEVAGTPPFEITWFKDNTILRS 1100



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%)

Query: 1007 IIAESQHPGGLEKIQYLEDASRYSKRTEEEV-KITQKPRFLGPLKGTNKIVEGQSAHFEA 1065
            II+  +   G    +   D  R S +    V  +   P F   LK  + I +G     E 
Sbjct: 1303 IISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSI-KGSFIDLEC 1361

Query: 1066 RVEPQSDLTMTVEWYFNGKQITSANRIQ-TYHDFGYVALDIASVRAEDSGVYTVVARNAA 1124
             V     ++  ++W+ + ++I+++ + + ++HD     L+I+ +   DSG YT  A N A
Sbjct: 1362 IVAGSHPIS--IQWFKDDQEISASEKYKFSFHD-NTAFLEISQLEGTDSGTYTCSATNKA 1418

Query: 1125 GEAQLSASMTVE 1136
            G  Q S  +TV+
Sbjct: 1419 GHNQCSGHLTVK 1430



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 3/84 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F + L  + ++  G + H E +++  S P +  +W+KDG+ I+ S++   + +   VS
Sbjct: 1902 PSFTKKLTKMDKVL-GSSIHMECKVSG-SLP-ISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGE 853
            L + +L  ED  +YT +  N  G+
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAGD 1982



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/78 (28%), Positives = 42/78 (53%), Gaps = 2/78 (2%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G    LEC++   G   + VEW+ +GK + +  + + ++     +L +LSV  +D+G YT
Sbjct: 2383 GETCTLECKV--AGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 2440

Query: 1385 CQATNQLGEAVTSCALRV 1402
             Q  N +G++  +  + V
Sbjct: 2441 FQVQNNVGKSSCTAVVDV 2458



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            A PP F  ++++ T  V G S   E ++       + V WF+   K+  G +Y+T     
Sbjct: 2462 AVPPSFTRRLKN-TGGVLGASCILECKVA--GSSPISVAWFHEKTKIVSGAKYQTTFSDN 2518

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            +  L +      + G Y CVA N  G D  +A L
Sbjct: 2519 VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVL 2552



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/76 (28%), Positives = 35/76 (46%)

Query: 790  FEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVN 849
            F  +      P +  +W+KDGR ++A S+    F     SL I      D G Y+    N
Sbjct: 3327 FALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKN 3386

Query: 850  KLGEAISTASIRVAAR 865
             +G++  T S+ V+ R
Sbjct: 3387 SVGKSNCTVSVHVSDR 3402



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 5/93 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH-TLNDFGF 3752
            PP F  +  D+++V  G  + F   +   G P  ++ WF   R    G   + +L DF  
Sbjct: 3498 PPSFE-QTPDSVEVLPGMSLTFTSVIR--GTPPFKVKWFKGSRELVPGESCNISLEDF-V 3553

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
              L++  +   ++G+Y+C  TN  GSA+ T  +
Sbjct: 3554 TELELFEVQPLESGDYSCLVTNDAGSASCTTHL 3586



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F +PL++++ +  G+ A   C++   G P +++ W++    +  +            S
Sbjct: 3685 PYFIEPLEHVEAVI-GEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVAS 3741

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+ V   D G Y C+A N +G
Sbjct: 3742 LVINKVDHSDVGEYSCKADNSVG 3764



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +KD+         FE R+   G   L+V W ++GV ++    L T        L
Sbjct: 3781 PFFARKLKDVHETLGFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHNVATL 3838

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             +   +    G Y C A N LG A +S+ L +
Sbjct: 3839 QILQTDQSHIGQYNCSASNPLGTASSSAKLIL 3870



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 8/107 (7%)

Query: 1967 AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF 2026
            +V + + +VEKP+      + +VT G    LE T+     P +  +W+ +G+ +   +++
Sbjct: 4246 SVLEPATIVEKPE------SIKVTTGDTCTLECTVA--GTPELSTKWFKDGKELTSDNKY 4297

Query: 2027 KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
            K ++      L I+     D+G Y  +  N VG+   T+S++V  ++
Sbjct: 4298 KISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT 4344



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P FT+ L   + L  G     E +V   G P +   W+  G E+  G +++TT       
Sbjct: 4347 PSFTRKLKETNGL-SGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 4403

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
            L +N +  +D+G Y C A N AG
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAG 4426



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 9/138 (6%)

Query: 3941 EALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPV 4000
            E + + E ++ + ++  +LT  +     +K PP F  Q++     V +    F+C ++  
Sbjct: 4695 EYICKAENSVGEVSASTFLTVQE-----QKLPPSFSRQLRDVQETVGLPVV-FDCAIS-- 4746

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
            G   + V W+ +GKPL         +      +N        +G+Y C ATN  G   + 
Sbjct: 4747 GSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSS 4806

Query: 4061 A-VIKTTGKPGIVYDSQL 4077
            A +I T GK    +D +L
Sbjct: 4807 ARLILTEGKNPPFFDIRL 4824



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 2/81 (2%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G +A FE  +T      ++V W KD R I +  +    +      L ++ +   D+G YT
Sbjct: 4832 GESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYT 4889

Query: 845  VRAVNKLGEAISTASIRVAAR 865
              AVN++G+   TA + +  R
Sbjct: 4890 CYAVNEVGKDSCTAQLNIKER 4910



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 65/276 (23%), Positives = 109/276 (39%), Gaps = 31/276 (11%)

Query: 4217 WYDETTQYQRTETELEKTFEERQVLQRQGVI---DHR-------PELK----PKVIKEPE 4262
            +Y+    Y   E E E+ ++ER+V+Q Q  +    H        PE K    PKVIK+P 
Sbjct: 5791 YYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPV 5850

Query: 4263 TEWQQSVKRKKNEE--YYNKLQELENEQV-IKESR--LRESTHQYAIPGDKVTSNTVAKS 4317
             E  +   R+  EE     K+ E+  + V  K SR  ++E   +  +P    T   V   
Sbjct: 5851 IEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVH-TKKMVISE 5909

Query: 4318 MAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKE 4377
                +  + ++   VT   VQK++  + +I       V          ++   E V    
Sbjct: 5910 EKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAVSKRVEPPPKVPELPEKPAPEEVAPVP 5969

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFE-HEQARFEVEFDG 4436
            I +K        +E  A     V + PV   K P+   K +P    +  E  +  V  + 
Sbjct: 5970 IPKK--------VEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEK 6021

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
             P+P+ K  ++  P    P+ Q    + + I I+ Q
Sbjct: 6022 IPVPVAK--KKEAPPAKVPEVQKGVVTEEKITIVTQ 6055



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F + +K  EV +   V LE  +T    P   V W  N R ++   ++  T    
Sbjct: 1616 VKEPPTFIRELKPVEVVKYSDVELECEVT--GTPPFEVTWLKNNREIRSSKKYTLTDRVS 1673

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067
               L I      DTG Y C  +N  G    ++ V
Sbjct: 1674 VFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRV 1707



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 3/100 (3%)

Query: 766  TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
            T + P F+  L+ L E   G +   + Q+     P + V WYK    +  +    + F  
Sbjct: 2740 TLEPPYFVTELEPL-EAAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTN 2796

Query: 826  GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
               +L    +   D+G YT +A N +G A S    R+  R
Sbjct: 2797 NVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 2836



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 8/102 (7%)

Query: 1968 VQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK 2027
            V + + ++EKP+   P+    VT G+P  LE  +T    P +  +W+ +GR +    +  
Sbjct: 3306 VLEPARIIEKPE---PMT---VTTGNPFALECVVT--GTPELSAKWFKDGRELSADSKHH 3357

Query: 2028 TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             T+     +L I  A   D G Y  +  N+VG++  T SV V
Sbjct: 3358 ITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHV 3399



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 47/228 (20%), Positives = 84/228 (36%), Gaps = 13/228 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F     D V++  G    + + +   G     ++WF   + +             + 
Sbjct: 3498 PPSFEQT-PDSVEVLPGMSLTFTSVI--RGTPPFKVKWFKGSRELVPGESCNISLEDFVT 3554

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LE+   +  +SG YSC  TN  G A  +  L   + +      F   + +   ++ G  
Sbjct: 3555 ELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPAT-----FVKRLADFS-VETGSP 3608

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               E T      P + + W  +   +  S R          +L+I  +   D  +Y C  
Sbjct: 3609 IVLEATYTGT--PPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLI 3666

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
             N+ G+D   A ++   +   ++E L+    A I E  +LQ     TP
Sbjct: 3667 ENEAGQDICEALVSVL-EPPYFIEPLEHVE-AVIGEPATLQCKVDGTP 3712



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 12/137 (8%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            GD    EC V     P L+  WF +G+++ + ++Y+ +       L I+     DSG Y 
Sbjct: 4265 GDTCTLECTVA--GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYS 4322

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKI--SP 2241
             +  N +G+   T +L+V+        T  P+   K++  E  G S    V E K+  SP
Sbjct: 4323 FEVQNPVGKDSCTASLQVSDR------TVPPSFTRKLK--ETNGLSGSSVVMECKVYGSP 4374

Query: 2242 PRFVTELRGTTHVFEGK 2258
            P  V+       +  G+
Sbjct: 4375 PISVSWFHEGNEISSGR 4391



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 3/110 (2%)

Query: 3263 LESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNG 3322
            +E+  G    +      EPP F+ Q++ V K+  G SA  + +L     P++ V W+   
Sbjct: 4607 IENASGKDSCSAQILILEPPYFVKQLEPV-KVSVGDSASLQCQLAGT--PEIGVSWYKGD 4663

Query: 3323 KKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             KL     Y+      +  L        +SGEY C A N +G  S    L
Sbjct: 4664 TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFL 4713



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 3/97 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L  ++ +  G++A  + +L  T  P + V WY     L+  + ++         
Sbjct: 4626 PYFVKQLEPVK-VSVGDSASLQCQLAGT--PEIGVSWYKGDTKLRPTTTYKMHFRNNVAT 4682

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
            L  +     DSGEY+C+A N+ GE   +  + VQ ++
Sbjct: 4683 LVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQK 4719



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 18/47 (38%), Positives = 28/47 (59%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICR 3905
            P ++ EW+RNG++L    R++T  +     L I  V AED G+Y C+
Sbjct: 5436 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 5482



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 2/100 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F+++ KS T    +  +F C V     P +   W ++G  L     +R         
Sbjct: 215  PPTFLSRPKSLTTFVGKAAKFICTVTGT--PVIETIWQKDGAALSPSPNWRISDAENKHI 272

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            L++  +  +D G Y C+A N FG D  +A +     P  I
Sbjct: 273  LELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFI 312



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            DR+   P FT+ L     +  G     + ++   G   +R  W+ +G E+    R+R   
Sbjct: 773  DRDIA-PFFTKPLRNVDSVVNGT-CRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAF 828

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
              G  +L+I  V  NDAG + C+A N  G
Sbjct: 829  VEGTASLEIIRVDMNDAGNFTCRATNSVG 857



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 9/124 (7%)

Query: 1973 FVVEKPQFGKPIKNAEVTE-GHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031
            FV E   F + ++ +++ + G    L   +T    P +++ W+ N R +++  + + ++ 
Sbjct: 959  FVKEPATFVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFV 1016

Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQEL 2091
                 L +     ED+G YMC+A N  G    +S V V  K   Y      +  K I+ L
Sbjct: 1017 ESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV--KESPYF----TKEFKPIEVL 1070

Query: 2092 EKYE 2095
            ++Y+
Sbjct: 1071 KEYD 1074



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E   F + L     L +G       +V   G P ++  W+ N  E+K  S+ R +     
Sbjct: 962  EPATFVEKLEPSQLLKKGDATQLACKVT--GTPPIKITWFANDREIKESSKHRMSFVEST 1019

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
              L +  V   D+G YMC+A N AG
Sbjct: 1020 AVLRLTDVGIEDSGEYMCEAQNEAG 1044



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 2/104 (1%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F  ++K     +   +  EC V       + I+W+++ + + +  +Y+  +      
Sbjct: 1339 PPSFTKKLKKMDSIKGSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            L+I  +   DSG Y C A N  G +     ++ K+ P  + + Q
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 1440



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F + L+ +  +   + +  + +        + ++W+KD + I+AS +    F+     
Sbjct: 1340 PSFTKKLKKMDSI---KGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 830  LNIMHLRAEDAGSYTVRAVNKLG 852
            L I  L   D+G+YT  A NK G
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAG 1419



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F K +K  +  +G  + LE  +       + ++W+ + + +    ++K ++      L
Sbjct: 1340 PSFTKKLKKMDSIKGSFIDLECIVA--GSHPISIQWFKDDQEISASEKYKFSFHDNTAFL 1397

Query: 2038 DILYAYAEDTGTYMCKATNAVG 2059
            +I      D+GTY C ATN  G
Sbjct: 1398 EISQLEGTDSGTYTCSATNKAG 1419



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F +  ++ +V     V L+A +       M ++W+ + + +  G       D  
Sbjct: 1429 VKEPPYFVEKPQSQDVNPNTRVQLKALVG--GTAPMTIKWFKDNKELHSGAARSVWKDDT 1486

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              +L++  A A D+GTY+C+ +N VG A + +++ V
Sbjct: 1487 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFV 1522



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 2/103 (1%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   P    ++ N+    + + +    + M ++WF + K L +G+      D     
Sbjct: 1432 PPYFVEKPQSQDVNPNTRV--QLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTS 1489

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            LE+      D+G Y C+ +N  G AT    L VK     I +P
Sbjct: 1490 LELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKP 1532



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 5/115 (4%)

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWF 1347
            QL  D    T +    + V + PQF +    +  +  G +   EC++   G   +RV W+
Sbjct: 1506 QLSNDVGTATSKAT--LFVKEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWY 1561

Query: 1348 CNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +G  I    +   ++        +     E+SG Y C+A N  G A  S  L+V
Sbjct: 1562 LDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKV 1616



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 39/223 (17%), Positives = 84/223 (37%), Gaps = 17/223 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F    ++   + +   A +++++   G   + I W  + + ++    +   +   + 
Sbjct: 1712 PPSFIKKIENTTTVLKSS-ATFQSTV--AGSPPISITWLKDDQILDEDDNVYISFVDSVA 1768

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L+I       SG Y+C+A N+ G         C      Q+P           + +   
Sbjct: 1769 TLQIRSVDNGHSGRYTCQAKNESGVE------RCYAFLLVQEPAQIVEKAKSVDVTEKDP 1822

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               EC V     P++K++W  +G+ +  S       +       I      DSG+Y  + 
Sbjct: 1823 MTLECVV--AGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKV 1880

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269
             N +G        +C     V  +++ P    K+ +++ + G+
Sbjct: 1881 ENDFGSS------SCDAYLRVLDQNIPPSFTKKLTKMDKVLGS 1917



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   VE   ++DV E  P+  +C V   G P +++ W  +G+            +    +
Sbjct: 1805 PAQIVEKAKSVDVTEKDPMTLECVV--AGTPELKVKWLKDGKQIVPSRYFSMSFENNVAS 1862

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTA 3783
              I  +  +D+G+YT +  N +GS++  A
Sbjct: 1863 FRIQSVMKQDSGQYTFKVENDFGSSSCDA 1891



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 10/124 (8%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP+F     +  I+    S+  EC++       +RV WF N   L    + +        
Sbjct: 2087 PPKFVKKLEASKIVKAGDSSRLECKI--AGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 2144

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
            ++++  +   D+G + C+A N  G  + S K+ VK       EP + S F    E+++  
Sbjct: 2145 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK-------EPPVFSSFPPIVETLKNA 2197

Query: 3676 EETL 3679
            E +L
Sbjct: 2198 EVSL 2201



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F  QL    + + G      CR+       ++V WY +G +L+     +TS     A 
Sbjct: 2840 PSFARQLKD-IEQTVGLPVTLTCRLNG--SAPIQVCWYRDGVLLRDHENLQTSFVDNVAT 2896

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            L IL      SG+Y+C A N LG A SS RL  +
Sbjct: 2897 LKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 2930



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 79/383 (20%), Positives = 131/383 (34%), Gaps = 25/383 (6%)

Query: 3546 DTLTPEAESGNPPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            D  + +     PP+F     +  +  +  S   EC++       ++V WF N   L    
Sbjct: 3017 DMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESW 3074

Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
            +          +L I      D+G Y C+A N  G+A+ S  L VK       +P     
Sbjct: 3075 KYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGA 3134

Query: 3665 FKSGTESIQKLEETLHKREEITIEDEKP--NPPRFTVEIKD--------NIDVPEGGPVH 3714
             K     +Q         E + ++D K   N  +F +  K         N++  + G  H
Sbjct: 3135 LKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYH 3194

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT- 3773
                 E VG  T          P      V  L+D   +  D   + A   G        
Sbjct: 3195 CKATNE-VGSDTCSCSVKFKEPP----RFVKKLSDTSTLIGDAVELRAIVEGFQPISVVW 3249

Query: 3774 -NKWGSATTTAKITCSAKRDIVLESQL--PQGM-SGEKIKELERGRISDAPKEEPIVSTP 3829
                G     ++ T  +  D +   QL  P+   SG+ I +++             V  P
Sbjct: 3250 LKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEP 3309

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
             + I + +  TV        EC V     P+L  +W+++G+ L +  ++   +     SL
Sbjct: 3310 ARIIEKPEPMTVTTGNPFALECVV--TGTPELSAKWFKDGRELSADSKHHITFINKVASL 3367

Query: 3890 DILYVYAEDSGEYICRAVNDFGE 3912
             I      D G Y     N  G+
Sbjct: 3368 KIPCAEMSDKGLYSFEVKNSVGK 3390



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKN-GQSIEASSRFTSIFRFGYI 694
            PP+F+  L   + + G  +     +E  G   + + WLK+ G+ I  S      F     
Sbjct: 3215 PPRFVKKLSDTSTLIGDAVELRAIVE--GFQPISVVWLKDRGEVIRESENTRISFIDNIA 3272

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            +L + S    +SG+Y C+  +  G+ E  AVL V   A I
Sbjct: 3273 TLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARI 3312



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F   +KD  +I  G     E R+   G + + V W +DG  + +  +  + F+     
Sbjct: 3406 PSFIRKLKDVNAIL-GASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L +  +   D G YTC A N  G    SA LT+
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 3495



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P  I +     K++ G +   EC +   P+  +  +W+ +GK L S ++Y+ S     + 
Sbjct: 4250 PATIVEKPESIKVTTGDTCTLECTVAGTPE--LSTKWFKDGKELTSDNKYKISFFNKVSG 4307

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            L I+ V   DSG Y+ +  N +G+   +  L V  +
Sbjct: 4308 LKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 4343



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 6/95 (6%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P  + E   +  V  G T   EC V     P L  +++ +GK L S  ++ I+F F  VS
Sbjct: 4250 PATIVEKPESIKVTTGDTCTLECTVAGT--PELSTKWFKDGKELTSDNKYKISF-FNKVS 4306

Query: 2302 -LDIQHCVPEDAGEYSVKAINALG--HCTSAISMT 2333
             L I +  P D+G YS +  N +G   CT+++ ++
Sbjct: 4307 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVS 4341



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L+  + +  G +   +C++   G P + V WF     I    +   T      +
Sbjct: 4347 PSFTRKLKETNGLS-GSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNTCA 4403

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            +T++ + + D G Y C A+N+ G
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAG 4426



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            ST + V+E K+ PP F  +LR       G    F+C +    +P + + +Y +GK L+ +
Sbjct: 4710 STFLTVQEQKL-PPSFSRQLRDVQETV-GLPVVFDCAISG-SEP-ISVSWYKDGKPLKDS 4765

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
                 +F     +L+I       AG+YS  A N +G  +S+  + +T
Sbjct: 4766 PNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILT 4812



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G++  FEC+V  ++   +K+ W  +++ + SG +Y+ ++  +   L +    + DSG YT
Sbjct: 4832 GESADFECHVTGTQP--IKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYT 4889

Query: 2848 CKATNSKGSATTSGSL 2863
            C A N  G  + +  L
Sbjct: 4890 CYAVNEVGKDSCTAQL 4905



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 3/95 (3%)

Query: 3557 PPEFTTTPSDLIL-SENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP FT   S+ +  +E +S   E R+       + V W+ N   +   S  +       +
Sbjct: 4913 PPSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTL 4970

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            +L++      DAGLYTCK +N  G A  +  + +K
Sbjct: 4971 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 5005



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI  L+    + G     +  +   G    +I W K+ + I +S ++    +   + 
Sbjct: 495 PPSFIKTLEPADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLFSQKSLVC 552

Query: 696 LDMLSLNIQDSGEYTCRAVSATG 718
           L++ S N  D GEY C   +  G
Sbjct: 553 LEIFSFNSADVGEYECVVANEVG 575



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 3/106 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   + D I++  G     +A +   G   + V W+K    +    +I   F+ G 
Sbjct: 587  EPPTFVKKVDDLIALG-GQTVTLQAAVR--GSEPISVTWMKGQEVIREDGKIKMSFSNGV 643

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
              L I  V +   G YTC A N  G  T+   L +     II  ++
Sbjct: 644  AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAE 689



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/59 (38%), Positives = 28/59 (47%)

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I WF  NK L SG     T +    SL++      DSG YTCK +N  G    S +L
Sbjct: 900  LTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANL 958



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 2/93 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P  IT+      +++G  A  + +     +  +  +W+ +G+ L  G +Y+ S     + 
Sbjct: 1243 PATITEEAVSIDVTQGDPATLQVKFSGTKE--ITAKWFKDGQELTLGSKYKISVTDTVSI 1300

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            L I++   +DSGEYT +  N++G++    R+NV
Sbjct: 1301 LKIISTEKKDSGEYTFEVQNDVGRSSCKARINV 1333



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 6/139 (4%)

Query: 1666 IAIVHSKKSIYLESQHEGALPRLN-QLEDTSKYQRHSAQDEVITQAPV-FTMPMKDIRVA 1723
            I+ V S  ++ + S   G   R   Q ++ S  +R  A   ++ Q P       K + V 
Sbjct: 1761 ISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAF--LLVQEPAQIVEKAKSVDVT 1818

Query: 1724 ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTY 1783
            E      E   +  G P+L+V+WL++G  I  S   +   +    +  ++ V  +DSG Y
Sbjct: 1819 EKDPMTLEC--VVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQY 1876

Query: 1784 TCRAINELGEAVTSSTLFV 1802
            T +  N+ G +   + L V
Sbjct: 1877 TFKVENDFGSSSCDAYLRV 1895



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 3/110 (2%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP F  +L     V  G + H EC+V       +  +++ +GK + ++A++ +      V
Sbjct: 1901 PPSFTKKLTKMDKVL-GSSIHMECKVSG--SLPISAQWFKDGKEISTSAKYRLVCHERSV 1957

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350
            SL++ +   ED   Y+ K  N  G    +  +TV    S + +  R + +
Sbjct: 1958 SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAI 2007



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 6/111 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP F   L+ T  V  G +   EC+V       + + ++H    + S A++  TF     
Sbjct: 2464 PPSFTRRLKNTGGVL-GASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVC 2520

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
            +L +      D G Y+  A N  G       +TV    S + E   PE LE
Sbjct: 2521 TLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKE---PEPLE 2568



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            SD  +    V  PP F+ + +   V   + V F   +  +  P  ++ W+R  + L  G 
Sbjct: 2545 SDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVI--RGTPPFKVNWFRGARELVKGD 2602

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            R    ++     L++  +    SGEY C   N+ G+
Sbjct: 2603 RCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQ 2638



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            VQ+ P F    +  + L  G++V   + +  R  P  K+ WF+    L  G R    F+ 
Sbjct: 2554 VQEPPSFVKEPEPLEVL-PGKNVTFTSVI--RGTPPFKVNWFRGARELVKGDRCNIYFED 2610

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             +  L + ++    SG YTC  +N  G+A  T  + +++
Sbjct: 2611 TVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE 2649



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 3/99 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E    P F   +KD I    G       RL   G + ++V W +DG  +     + T 
Sbjct: 2833 IQERQLPPSFARQLKD-IEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDHENLQTS 2889

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000
            F      L I    +  +G Y+C A N +G A++SA LT
Sbjct: 2890 FVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLT 2928



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            I +  G  A FE  +   G   +R+ W KD + +      T         L I  V   D
Sbjct: 2945 IDVIAGESADFECHVT--GAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGD 3002

Query: 979  AGHYTCRAYNAIGQATTSANLTI 1001
            +G YTC+A N +G+   SA L++
Sbjct: 3003 SGQYTCQATNDVGKDMCSAQLSV 3025



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 2/94 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F     D+     +S   ECR+     + + V WF +G  +++G + ++        
Sbjct: 3405 PPSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            L +  +   D G+YTC A N  G    S  L V+
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 3496



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR-TFHDFG 3338
            EPP F  Q  D  +++ G S  F +  V    P  KV+WF   ++L  G     +  DF 
Sbjct: 3497 EPPSF-EQTPDSVEVLPGMSLTFTS--VIRGTPPFKVKWFKGSRELVPGESCNISLEDF- 3552

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            +  L++       SG+Y C+ TN  G  S   +L
Sbjct: 3553 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHL 3586



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2129 FECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATN 2188
            FECR+   ++P L + W+ +G  ++     +T+       L IL T     G Y C A+N
Sbjct: 3800 FECRING-SEP-LQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASN 3857

Query: 2189 KLGEAVNTCTLKVAGH 2204
             LG A ++  L ++ H
Sbjct: 3858 PLGTASSSAKLILSEH 3873



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  P   + + +S  V   +    EC V     P+L  +W+++GK L S ++Y+  +   
Sbjct: 4247 VLEPATIVEKPESIKVTTGDTCTLECTVAGT--PELSTKWFKDGKELTSDNKYKISFFNK 4304

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               L I+ V   DSG Y     N  G+D   A++
Sbjct: 4305 VSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASL 4338



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F  QL    + + G    ++C I    +P + V WY +GK L+     +TS     A 
Sbjct: 4722 PSFSRQLRDVQE-TVGLPVVFDCAISG-SEP-ISVSWYKDGKPLKDSPNVQTSFLDNTAT 4778

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934
            L+I       +G+Y+C A N +G A SS RL
Sbjct: 4779 LNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F + +  +     ++A FE  +   G   ++V W ++   I +  +    +      L
Sbjct: 4818 PFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHL 4875

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             +  V+  DSG YTC A+NE+G+   ++ L ++ +
Sbjct: 4876 TVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER 4910



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 5/121 (4%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            + ++ ++E ++ PP F   L  T    EG +   E +V       + + +Y N   +Q  
Sbjct: 4902 TAQLNIKE-RLIPPSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPT 4958

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAISMTVTAKGSIISESQR 2346
            +   ITF    + L ++     DAG Y+ K  N  G   CTS+I +    K  +  +   
Sbjct: 4959 SNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 5018

Query: 2347 P 2347
            P
Sbjct: 5019 P 5019



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            N   H EC++    D  + V W  +G+ L  G   K   +     LEI     +D+G Y 
Sbjct: 323  NKKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYV 380

Query: 3632 CKATNRHGEATVSCKLQVK 3650
            C A+N  G ++ S  + V+
Sbjct: 381  CTASNEAGSSSCSATVTVR 399



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2646 THLKSYDKLVE--GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            T +K  D L+   GQ V L+A V  R    + + W K    +    ++K +F  G+  L 
Sbjct: 590  TFVKKVDDLIALGGQTVTLQAAV--RGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLI 647

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            I  ++    G YTC A N  G   S   + +++
Sbjct: 648  IPDVQISFGGKYTCLAENEAGSQTSVGELIVKE 680



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/128 (25%), Positives = 52/128 (40%), Gaps = 4/128 (3%)

Query: 3793 IVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECR 3852
            I+ + Q+  G     + E E G  S     E IV  P K I + +   V   +    E  
Sbjct: 647  IIPDVQISFGGKYTCLAENEAG--SQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYT 704

Query: 3853 VEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            V     P+L+ +WY++G+ L +  +YR  +      L        DSG+Y     N+ G 
Sbjct: 705  VAGT--PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGS 762

Query: 3913 DFTKATIS 3920
               + T +
Sbjct: 763  SSCETTFT 770



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 4/90 (4%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F   +++V  +V G +   + ++       ++V WF +GK++    RYR     G   
Sbjct: 778  PFFTKPLRNVDSVVNG-TCRLDCKIA--GSLPMRVSWFKDGKEIAASDRYRIAFVEGTAS 834

Query: 3342 LDILYCYEENSGEYECVATNKLG-RDSTKA 3370
            L+I+     ++G + C ATN +G +DS+ A
Sbjct: 835  LEIIRVDMNDAGNFTCRATNSVGSKDSSGA 864



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/137 (21%), Positives = 63/137 (45%), Gaps = 11/137 (8%)

Query: 1533 RLTCRSTTDIVRSTQ---NEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEI 1589
            R++   +T ++R T     ++G    +   +    H + +V  +  ++P  T   K +E+
Sbjct: 1012 RMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIV--IVKESPYFTKEFKPIEV 1069

Query: 1590 KEGQRAHFERRLIPVSDAT--LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDS 1647
             +     ++  L+     T   ++ W+ +N  L+SG ++        V+L I+  +  D+
Sbjct: 1070 LK----EYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADA 1125

Query: 1648 GTYTCRAINALGEAVTS 1664
            G Y CR  N +G ++ S
Sbjct: 1126 GEYQCRVTNEVGSSICS 1142



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 18/61 (29%), Positives = 30/61 (49%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KD   + +  +  +      VSL I+   A DAG Y  R  N++G +I +A 
Sbjct: 1085 PPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSAR 1144

Query: 860  I 860
            +
Sbjct: 1145 V 1145



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR-TFHDFGI 3339
            PP F  +++ +   ++G     E  +V    P + ++WF + +++    +Y+ +FHD   
Sbjct: 1339 PPSFTKKLKKMDS-IKGSFIDLEC-IVAGSHP-ISIQWFKDDQEISASEKYKFSFHD-NT 1394

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L+I      +SG Y C ATNK G +    +L
Sbjct: 1395 AFLEISQLEGTDSGTYTCSATNKAGHNQCSGHL 1427



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F    +S D +     V L+A V   T P + I+WFK+   L +GA      D 
Sbjct: 1429 VKEPPYFVEKPQSQD-VNPNTRVQLKALVGG-TAP-MTIKWFKDNKELHSGAARSVWKDD 1485

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               +L + + +  DSG Y C+ +N +G A S A++ +++
Sbjct: 1486 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE 1524



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 19/82 (23%), Positives = 41/82 (50%), Gaps = 2/82 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +V + G +  FEC +  +  P +++ W+ +   + +  ++  +      +  I+    E+
Sbjct: 1536 LVLRNGQSTTFECQITGT--PKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVEN 1593

Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864
            SG Y C+A N  G+A+ S  L+
Sbjct: 1594 SGTYVCEARNDAGTASCSIELK 1615



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 2/89 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + P     LK VE+ +      E  +        +V W  NN+ ++S  ++T T+     
Sbjct: 1618 EPPTFIRELKPVEVVKYSDVELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTDRVSVF 1675

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
             L I  C P D+G Y C   N  G    S
Sbjct: 1676 NLHITKCDPSDTGEYQCIVSNEGGSCSCS 1704



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E  Q  +  K+ +VTE  P+ LE  +     P ++V+W  +G+ +     F  +++  
Sbjct: 1802 VQEPAQIVEKAKSVDVTEKDPMTLECVVA--GTPELKVKWLKDGKQIVPSRYFSMSFENN 1859

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              +  I     +D+G Y  K  N  G +   + ++V
Sbjct: 1860 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV 1895



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            E D +  EC V  +  P LK++W  + K +     +  + + +  S  I    ++DSG Y
Sbjct: 1819 EKDPMTLECVVAGT--PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQY 1876

Query: 2847 TCKATNSKGSATTSGSLRCTGDKNI 2871
            T K  N  GS++    LR   D+NI
Sbjct: 1877 TFKVENDFGSSSCDAYLRVL-DQNI 1900



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P FT+ LT   ++  G   H E +V   G   +  +W+ +G E+   +++R       V+
Sbjct: 1902 PSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVS 1958

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
            L++N++   D   Y CK  N AG
Sbjct: 1959 LEVNNLELEDTANYTCKVSNVAG 1981



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 4/95 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   VE    + V  G     +C+V   G P + ++W+ +G+   T S+ H  + +  I+
Sbjct: 2368 PAVIVEKAGPMTVTVGETCTLECKV--AGTPELSVEWYKDGK-LLTSSQKHKFSFYNKIS 2424

Query: 3755 -LDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
             L I  +  +DAG YT +  N  G ++ TA +  S
Sbjct: 2425 SLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVS 2459



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 37/160 (23%), Positives = 71/160 (44%), Gaps = 15/160 (9%)

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTT 1575
            I T    N+V T++     TC    +I+ ST+ +AG    ++  +  +     +V   T 
Sbjct: 2691 ITTSEKCNIVTTEK-----TC--ILEILNSTKRDAGQYSCEIENEAGRDVCGALVS--TL 2741

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE--TNNFG 1633
            + P   T L+ +E   G     + ++    + T  V WY  +  L+    +    TNN  
Sbjct: 2742 EPPYFVTELEPLEAAVGDSVSLQCQVAGTPEIT--VSWYKGDTKLRPTPEYRTYFTNNVA 2799

Query: 1634 FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
             +  + ++    DSG YTC+A N++G A +  +  +  ++
Sbjct: 2800 TLVFNKVNI--NDSGEYTCKAENSIGTASSKTVFRIQERQ 2837



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F + L       +G+    E ++   G P ++  W+ N  EL    ++  +     
Sbjct: 3027 EPPKFVKKLEASKVAKQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSV 3084

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
              L IN   A D+G Y+C+A N  G
Sbjct: 3085 ALLTINEASAEDSGDYICEAHNGVG 3109



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V+  P+FT        L +G  V L+ ++     P  ++ W K+   +    + K T   
Sbjct: 3119 VKAPPVFTQKPSPVGAL-KGSDVILQCEISGT--PPFEVVWVKDRKQVRNSKKFKITSKH 3175

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                L I +L   D G Y CKATN +G    + S+K ++
Sbjct: 3176 FDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE 3214



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P  +     P  V+ G    LEC +   G P +  +WF +GR ++  S+    +     
Sbjct: 3308 EPARIIEKPEPMTVTTGNPFALECVVT--GTPELSAKWFKDGRELSADSKHHITFINKVA 3365

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            +L I  A  +D G Y+    N +G ++ +  V V +R
Sbjct: 3366 SLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDR 3402



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 20/75 (26%), Positives = 34/75 (45%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            K  P   + W+     L  G R  ++ +     L+L DV    SG YTC   N+ G+A  
Sbjct: 4464 KGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASC 4523

Query: 2998 SSTVYCTSKDNLIER 3012
            ++ +Y  +    ++R
Sbjct: 4524 TTHLYIKAPAKFVKR 4538



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L  +    GD+   +C +  +  P + + W+  +  L   T YK     +  +L  
Sbjct: 4628 FVKQLEPVKVSVGDSASLQCQLAGT--PEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVF 4685

Query: 2836 THTYEEDSGIYTCKATNSKGSATTS 2860
                  DSG Y CKA NS G  + S
Sbjct: 4686 NQVDINDSGEYICKAENSVGEVSAS 4710



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)

Query: 4086 KIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWL 4145
            K+     S   T   V++E K   PPVF      VTV EGE+ +  C V G    R+ WL
Sbjct: 4988 KVSNDAGSALCTSSIVIKEPKK--PPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWL 5045

Query: 4146 LNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTG 4178
              G  I    R   ++  G    ++    + D+G
Sbjct: 5046 KAGREIKPSDRCSFSFASGTAVLELRDVAKADSG 5079



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 3/79 (3%)

Query: 2779 HLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHT 2838
            HL ++  KEG              P +K EWF N + L    R+K+  +     L I   
Sbjct: 5415 HLQDVTLKEGQTCTMTVQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADV 5471

Query: 2839 YEEDSGIYTCKATNSKGSA 2857
              ED G YTCK  + + SA
Sbjct: 5472 RAEDQGQYTCKYEDLETSA 5490



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 18/47 (38%), Positives = 26/47 (55%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCK 2987
            P++K EW+ NG++L+   R K   +     L + DV   D G YTCK
Sbjct: 5436 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 5482



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVR----FECRVEPKEDPKLRIEWYRNGKLLP 3873
            +AP    + + P KF+ +IK   + ESE V     FEC V P         W ++G  + 
Sbjct: 7790 EAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPST---AITTWMKDGSNIR 7846

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
               ++R + D     L I+ V   D+GEY C       E  + A +  ++LP
Sbjct: 7847 ESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP 7898



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            VH +C+V+   D  + + W  +G+    G       +     L+I     +D+G Y C A
Sbjct: 326  VHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTA 383

Query: 3773 TNKWGSATTTAKIT 3786
            +N+ GS++ +A +T
Sbjct: 384  SNEAGSSSCSATVT 397



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 46/172 (26%), Positives = 74/172 (43%), Gaps = 14/172 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L   + ++ G  A  +C V         I WF + ++IR+  +YR       V 
Sbjct: 496  PSFIKTLEPADIVR-GTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLFSQKSLVC 552

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGH 2228
            L+I    + D G Y C   N++G+    C   +A H    L  + P  ++K+  L A G 
Sbjct: 553  LEIFSFNSADVGEYECVVANEVGKC--GC---MATH----LLKEPPTFVKKVDDLIALGG 603

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFE-GK-TAHFECQVEPVHDPNLRIEF 2278
             T       + S P  VT ++G   + E GK    F   V  +  P+++I F
Sbjct: 604  QTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISF 655



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            I Q+P       G+  ++ G +   ++    Q    +T+ W+   K++ S        + 
Sbjct: 866  IVQEPPSFVTKPGSKDVLPGSAVCLKSTF--QGSTPLTIRWFKGNKELVSGGSCYITKEA 923

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
               +L++  V+  DSG YT    N AG  + SA++ V+
Sbjct: 924  LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 961



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P FT+    P E+ +       A V   G P     W+ +   L+ G +++T      
Sbjct: 1056 ESPYFTKEFK-PIEVLKEYDVMLLAEVA--GTPPFEITWFKDNTILRSGRKYKTFIQDHL 1112

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
            V+L I   VA DAG Y C+  N  G
Sbjct: 1113 VSLQILKFVAADAGEYQCRVTNEVG 1137



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/72 (27%), Positives = 34/72 (47%)

Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            ++W+ + + + +  +Y+ S     A L+I  + G DSG YTC A N  G    S  L V+
Sbjct: 1371 IQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 1430

Query: 1938 SKESIIRDSQHE 1949
                 +   Q +
Sbjct: 1431 EPPYFVEKPQSQ 1442



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 5/137 (3%)

Query: 1801 FVQSKASLQLESQHESALQKIQ-QLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
            FV S A+LQ+ S       +   Q ++ S  +R       + Q P  I +      ++E 
Sbjct: 1763 FVDSVATLQIRSVDNGHSGRYTCQAKNESGVERC--YAFLLVQEPAQIVEKAKSVDVTEK 1820

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
                 EC +   P+  ++V+W  +GK +     +  S +   A+  I +V  +DSG+YT 
Sbjct: 1821 DPMTLECVVAGTPE--LKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTF 1878

Query: 1920 KAINNLGQAVSSIRLNV 1936
            K  N+ G +     L V
Sbjct: 1879 KVENDFGSSSCDAYLRV 1895



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/98 (20%), Positives = 48/98 (48%), Gaps = 2/98 (2%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            +T+ P+F+  L+ +  +  G S+  E ++    ++   V W+ N  ++ ++++ +     
Sbjct: 2084 VTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIR--VVWFRNEHELPASDKYRMTFID 2141

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                + + ++  EDSG +   A+N AG    S  + V+
Sbjct: 2142 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 2179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 2/94 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F++ P  +   +N+    EC L         V W+ + + L +  + K  +      
Sbjct: 2181 PPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNFHTS 2238

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            + I  V   D G Y CKA N  G  T  C +++K
Sbjct: 2239 IHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLK 2272



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G    LE  +     P + VEWY +G+ +    + K ++     +L IL    +D G
Sbjct: 2380 VTVGETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAG 2437

Query: 2049 TYMCKATNAVGEAVTTSSVKVDAKS 2073
            TY  +  N VG++  T+ V V  ++
Sbjct: 2438 TYTFQVQNNVGKSSCTAVVDVSDRA 2462



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 2/81 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L N     G +   EC V  S    + + WF     + SG +Y++T   +  +L +
Sbjct: 2467 FTRRLKNTGGVLGASCILECKVAGSSP--ISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 2524

Query: 2836 THTYEEDSGIYTCKATNSKGS 2856
                  D G YTC A N  GS
Sbjct: 2525 NSLDSSDMGNYTCVAANVAGS 2545



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 3/90 (3%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            + PP FVTEL        G +   +CQV     P + + +Y     L+    +   F   
Sbjct: 2741 LEPPYFVTELE-PLEAAVGDSVSLQCQVAGT--PEITVSWYKGDTKLRPTPEYRTYFTNN 2797

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              +L        D+GEY+ KA N++G  +S
Sbjct: 2798 VATLVFNKVNINDSGEYTCKAENSIGTASS 2827



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  Q++D+ + V G       RL       ++V W+ +G  L      +T     + 
Sbjct: 2839 PPSFARQLKDIEQTV-GLPVTLTCRLN--GSAPIQVCWYRDGVLLRDHENLQTSFVDNVA 2895

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             L IL     +SG+Y C A+N LG  S+ A L
Sbjct: 2896 TLKILQTDLSHSGQYSCSASNPLGTASSSARL 2927



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/65 (30%), Positives = 29/65 (44%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G + +++ W KD R +                LT+  V   DAG YTC A N  G+ + S
Sbjct: 3902 GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCS 3961

Query: 997  ANLTI 1001
            A L +
Sbjct: 3962 AQLGV 3966



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 11/110 (10%)

Query: 2229 STRIEVEEPKI--SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ 2286
            ST ++V+EP I    P  +  L+G          H EC+++    P   + +Y + + L+
Sbjct: 4055 STSLKVKEPPIFRKKPHPIETLKGAD-------VHLECELQGT--PPFHVSWYKDKRELR 4105

Query: 2287 SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
            S  ++ I  +    S+ I +    D GEY  KA N +G  T   S+ + A
Sbjct: 4106 SGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA 4155



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 38/174 (21%), Positives = 73/174 (41%), Gaps = 11/174 (6%)

Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081
            Y+E+AS        ++ I + P F+  L+   K+  G SA  + ++    ++   V WY 
Sbjct: 4606 YIENASGKDS-CSAQILILEPPYFVKQLEPV-KVSVGDSASLQCQLAGTPEIG--VSWYK 4661

Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
               ++      + +       L    V   DSG Y   A N+ GE   S  +TV+ +   
Sbjct: 4662 GDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLP 4721

Query: 1142 DTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
             + S       + R ++E+  +  ++    IS S+P+ V    +  P+ +  N+
Sbjct: 4722 PSFS------RQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPLKDSPNV 4768



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F + L  P ++  G  A  + ++   G P +   WY    +L+  + ++       
Sbjct: 4624 EPPYFVKQLE-PVKVSVGDSASLQCQLA--GTPEIGVSWYKGDTKLRPTTTYKMHFRNNV 4680

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             TL  N V  ND+G Y+CKA N  G
Sbjct: 4681 ATLVFNQVDINDSGEYICKAENSVG 4705



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F + L+ +  +  G +A   C+L   G P + V W++ +  +  ++           +
Sbjct: 4626 PYFVKQLEPV-KVSVGDSASLQCQL--AGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVAT 4682

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            +  + V   D G Y+C+A N +GE
Sbjct: 4683 LVFNQVDINDSGEYICKAENSVGE 4706



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 2/104 (1%)

Query: 3544 TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTG 3603
            +  T     E   PP F+    D+  +      F+C +       + V W+ +GKPL   
Sbjct: 4708 SASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDS 4765

Query: 3604 SRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
              V+T        L I    +  AG Y+C ATN  G A+ S +L
Sbjct: 4766 PNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 3/90 (3%)

Query: 1585 KNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLP 1644
            + VE  EG     E R+       + V WY NN  ++  S    T     + L +     
Sbjct: 4922 ETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGM 4979

Query: 1645 EDSGTYTCRAINALGEAV-TSGIAIVHSKK 1673
             D+G YTC+  N  G A+ TS I I   KK
Sbjct: 4980 NDAGLYTCKVSNDAGSALCTSSIVIKEPKK 5009



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984
            EG    LEG+V       + + WY N   ++  S  ++T     + L +      D+G+Y
Sbjct: 4928 EGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLY 4985

Query: 2985 TCKAYNKRGEAFTSSTV 3001
            TCK  N  G A  +S++
Sbjct: 4986 TCKVSNDAGSALCTSSI 5002



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 57/279 (20%), Positives = 99/279 (35%), Gaps = 31/279 (11%)

Query: 995  TSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNK 1054
            T  N T+V +  +     +  GL   +   DA      +   +K  +KP           
Sbjct: 4964 TFKNNTLVLQ--VRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT 5021

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            + EG+       V  Q    + ++W   G++I  ++R       G   L++  V   DSG
Sbjct: 5022 VSEGEYVQLSCHV--QGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSG 5079

Query: 1115 VYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISK 1174
             Y   A N AG     + +T++ + ++  ++      +K        FV     I  + K
Sbjct: 5080 DYVCKASNVAGSDTTKSKVTIKDKPAVAPAT------KKAAVDGRLFFVSEPQSIRVVEK 5133

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFH-NGRSVTVGSRFKTYYDFG 1233
            +   F+  +                     GDP   V+W     R +  G R   +    
Sbjct: 5134 TTATFIAKVG--------------------GDPIPNVKWTKGKWRQLNQGGRVFIHQKGD 5173

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
               L+I   T  D+G Y   A N  G   ++  ++V ER
Sbjct: 5174 EAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 5212



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+   KS+T   G    F   +   G P ++  W K+G ++  S  +          
Sbjct: 215 PPTFLSRPKSLTTFVGKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWRISDAENKHI 272

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVL 726
           L++ +L IQD G Y+C+A +  G    +A L
Sbjct: 273 LELSNLTIQDRGVYSCKASNKFGADICQAEL 303



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1848 TQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALD 1905
            T L+ P  L+   G++A + C +     P +   W  +G  L     +R S+      L+
Sbjct: 217  TFLSRPKSLTTFVGKAAKFICTVTG--TPVIETIWQKDGAALSPSPNWRISDAENKHILE 274

Query: 1906 ILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH-ESALEKIQYLE 1959
            +  +  +D G Y+CKA N  G  +    L +  K   I++ +  +SA+ K  +LE
Sbjct: 275  LSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLE 329



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
           +P FI+ L+ + +    +  H E Q+    D  + V W KDG+ +         F     
Sbjct: 308 KPHFIKELEPV-QSAINKKVHLECQVD--EDRKVTVTWSKDGQKLPPGKDYKICFEDKIA 364

Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           +L I   + +D+G+Y   A N+ G +  +A++ V
Sbjct: 365 TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 398



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 1974 VVEKPQFGKPIKNAEVT-EGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P F K +  + +   G    L   L     P ++V W+ N + + + +  +  +  
Sbjct: 398  VREPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVN 455

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                LDI     ED+G+Y C+A N VG    ++ + +
Sbjct: 456  SEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI 492



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ I + P F+  L+  + IV G +A  +  V         + W+ + KQI S+ + + +
Sbjct: 489  EIVIKEPPSFIKTLEPAD-IVRGTNALLQCEVSGTGPFE--ISWFKDKKQIRSSKKYRLF 545

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSAS 1132
                 V L+I S  + D G Y  V  N  G+    A+
Sbjct: 546  SQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMAT 582



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 9/118 (7%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+  +  + A+ G  +  +  +   G   + + W+K  + I    +    F  G   
Sbjct: 588 PPTFVKKVDDLIALGGQTVTLQAAVR--GSEPISVTWMKGQEVIREDGKIKMSFSNGVAV 645

Query: 696 LDMLSLNIQDSGEYTC----RAVSATGVAE--TKAVLHVTPRA-TIERTSQHPETLQY 746
           L +  + I   G+YTC     A S T V E   K    +  RA  I+ T+  P TL+Y
Sbjct: 646 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEY 703



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 19/68 (27%), Positives = 32/68 (47%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P +K +W K+G+ + AS ++   F+     L   S  + DSG+YT    +  G +  +
Sbjct: 707 GTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCE 766

Query: 724 AVLHVTPR 731
               V  R
Sbjct: 767 TTFTVLDR 774



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 3/116 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V + P F     + + + G+ V L+   Q  G   + + WF   K + +G       E
Sbjct: 865  LIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQ--GSTPLTIRWFKGNKELVSGGSCYITKE 922

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK 1420
                +L+L  V   DSG YTC+ +N  G    S  L  + +    +E   PS L K
Sbjct: 923  ALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANL-FVKEPATFVEKLEPSQLLK 977



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/126 (25%), Positives = 50/126 (39%), Gaps = 3/126 (2%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV  PP F+T+  S  V     V  +   +      L I W++  K L SG       + 
Sbjct: 866  IVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTP--LTIRWFKGNKELVSGGSCYITKEA 923

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
               SL++  V   DSG Y C+  N  G     A +  K+ P   ++   P  + +    T
Sbjct: 924  LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE-PATFVEKLEPSQLLKKGDAT 982

Query: 3945 QMEATI 3950
            Q+   +
Sbjct: 983  QLACKV 988



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 3/102 (2%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P FI+ ++    L+ G  A F+A L   S P + V W KD   IT    I   F     S
Sbjct: 1151 PSFIKKIESTSSLRGG-TAAFQATLKG-SLP-ITVTWLKDSDEITEDDNIRMTFENNVAS 1207

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTAD 871
            L +  +  +  G Y  +A N  G    +A + V   +T+T +
Sbjct: 1208 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEE 1249



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 23/98 (23%), Positives = 51/98 (52%), Gaps = 6/98 (6%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            QV+     ++  +W+ +G+ L  GS++K++       L ++   ++DSG YT +  N  G
Sbjct: 1264 QVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVG 1323

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDS 3031
             +       C ++ N+++    P  T+ L+K+ +++ S
Sbjct: 1324 RS------SCKARINVLDLIIPPSFTKKLKKMDSIKGS 1355



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 4/94 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT-TMHDFGYVA 1769
            P FT  +K  ++   + +  +   I  G   + ++W ++   I AS +   + HD     
Sbjct: 1340 PSFTKKLK--KMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHD-NTAF 1396

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            L +  +   DSGTYTC A N+ G    S  L V+
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 1430



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YD 4162
            E K + PP F+     V V +       C VTG P   V WL N   I +  +Y LT   
Sbjct: 1613 ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV 1672

Query: 4163 GMYHFDIPKTRQYDTGKIEVI 4183
             +++  I K    DTG+ + I
Sbjct: 1673 SVFNLHITKCDPSDTGEYQCI 1693



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F+ +++    +V+    + EC++   G P  +V W  N + +    ++T      
Sbjct: 1617 KEPPTFIRELKP-VEVVKYSDVELECEVT--GTPPFEVTWLKNNREIRSSKKYTLTDRVS 1673

Query: 4030 YVAMNFGWVYPEDSGEYLCRATN 4052
               ++     P D+GEY C  +N
Sbjct: 1674 VFNLHITKCDPSDTGEYQCIVSN 1696



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 18/83 (21%), Positives = 38/83 (45%), Gaps = 2/83 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F K +   +   G  +H+E  ++      +  +W+ +G+ +    +++       V+L
Sbjct: 1902 PSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSL 1959

Query: 2038 DILYAYAEDTGTYMCKATNAVGE 2060
            ++     EDT  Y CK +N  G+
Sbjct: 1960 EVNNLELEDTANYTCKVSNVAGD 1982



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 19/79 (24%), Positives = 42/79 (53%), Gaps = 2/79 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+    EC+V     P L+++W+ +G+ + +  +++ +      +L IL    +D+GTY 
Sbjct: 2383 GETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 2440

Query: 2184 CKATNKLGEAVNTCTLKVA 2202
             +  N +G++  T  + V+
Sbjct: 2441 FQVQNNVGKSSCTAVVDVS 2459



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 8/104 (7%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG---VPIEASNRLTTMH 1763
            + + P F      + V    +  F +  +  G P  +V+W +     VP E+ N   ++ 
Sbjct: 3495 VQEPPSFEQTPDSVEVLPGMSLTFTS--VIRGTPPFKVKWFKGSRELVPGESCN--ISLE 3550

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            DF    L +  V P +SG Y+C   N+ G A  ++ LFV+  A+
Sbjct: 3551 DF-VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPAT 3593



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 18/63 (28%), Positives = 33/63 (52%)

Query: 2674 LKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733
            +KI W K+   +  G   K T      TL++  +   D+G YTC A+N+ G+   +A + 
Sbjct: 3906 IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLG 3965

Query: 2734 IED 2736
            +++
Sbjct: 3966 VQE 3968



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 3/107 (2%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            + V + P F+ Q   P  +  G +  +   ++  P     V W+     L  G R   S 
Sbjct: 4434 LTVREPPSFV-QKPDPMDVLTGTNVTFTSIVKGTPP--FSVSWFKGSSELVPGDRCNVSL 4490

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            +   A L++  V    SGEYTC   N  G+A  +  L +++    ++
Sbjct: 4491 EDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVK 4537



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            ++    +F K + +  + +G P+ LE T T    P + V W  NG  V    R   T   
Sbjct: 4528 YIKAPAKFVKRLNDYSIEKGKPLILEGTFT--GTPPISVTWKKNGINVTPSQRCNITTTE 4585

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L+I  +  ED G Y C   NA G+   ++ + +
Sbjct: 4586 KSPILEIPSSTVEDAGQYNCYIENASGKDSCSAQILI 4622



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            + PP FV +L     V  G +A  +CQ+     P + + +Y     L+    + + F   
Sbjct: 4623 LEPPYFVKQLE-PVKVSVGDSASLQCQLAGT--PEIGVSWYKGDTKLRPTTTYKMHFRNN 4679

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              +L        D+GEY  KA N++G  +++  +TV
Sbjct: 4680 VATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV 4715



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 2/94 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   L+ V    G  + F+  I   G   + + W K+G+ ++ S    + F     +
Sbjct: 4721 PPSFSRQLRDVQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNVQTSFLDNTAT 4778

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
            L++   +   +G+Y+C A +  G A + A L +T
Sbjct: 4779 LNIFKTDRSLAGQYSCTATNPIGSASSSARLILT 4812



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F+  L+   + V G  V  +  +   ++P + + W+K+G  L     ++++F     T
Sbjct: 4722 PSFSRQLRDVQETV-GLPVVFDCAISG-SEP-ISVSWYKDGKPLKDSPNVQTSFLDNTAT 4778

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
            L+I       +G Y+C ATN +G A S+A +
Sbjct: 4779 LNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 3/86 (3%)

Query: 636  PPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            PP F   L ++V   EG     E R+   G   + + W KN   I+ +S     F+   +
Sbjct: 4913 PPSFTKRLSETVEETEGNSFKLEGRV--AGSQPITVAWYKNNIEIQPTSNCEITFKNNTL 4970

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVA 720
             L +    + D+G YTC+  +  G A
Sbjct: 4971 VLQVRKAGMNDAGLYTCKVSNDAGSA 4996



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 6/108 (5%)

Query: 1033 TEEEVKITQKP-RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR 1091
            T  E++I  +P +F   ++    + E QSA FE  V     +   V WY    ++T + +
Sbjct: 5488 TSAELRIEAEPIQFTKRIQNI-VVSEHQSATFECEVSFDDAI---VTWYKGPTELTESQK 5543

Query: 1092 IQTYHDFGYVALDIASVRAEDSGVYTVVAR-NAAGEAQLSASMTVETR 1138
                +D     + I +V  +D GVY+V+AR    GEA+ +A + + T+
Sbjct: 5544 YNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTK 5591



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 10/129 (7%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F++RPKS+   + G+   F C +       ++  W K+G  ++    +R         
Sbjct: 216  PTFLSRPKSLTTFV-GKAAKFICTVTGTPV--IETIWQKDGAALSPSPNWRISDAENKHI 272

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L++ +L  +D G+Y+C+A N  G D       C++   I+        LE +Q   ++ K
Sbjct: 273  LELSNLTIQDRGVYSCKASNKFGAD------ICQAELIIIDKPHFIKELEPVQSAINK-K 325

Query: 1564 YHRTDMVDE 1572
             H    VDE
Sbjct: 326  VHLECQVDE 334



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/158 (22%), Positives = 64/158 (40%), Gaps = 5/158 (3%)

Query: 2926 GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
            GQ + L+  V  +    + + W    +V+ +  + K++   G   L + DV     G YT
Sbjct: 603  GQTVTLQAAV--RGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYT 660

Query: 2986 CKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD-DDT 3044
            C A N+ G   +   +       +IER +  + T G      LE ++   P  +P     
Sbjct: 661  CLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAG--DPATLEYTVAGTPELKPKWYKD 718

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVI 3082
            GRP   +  ++     +  Q+  Y A L  +G  +  I
Sbjct: 719  GRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEI 756



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 19/86 (22%), Positives = 37/86 (43%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E    P  +I W+ +  +L  G ++K       V+L ++     D+G Y C+  N+ G +
Sbjct: 1080 EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 1139

Query: 2996 FTSSTVYCTSKDNLIERTQHPKGTEG 3021
              S+ V      + I++ +      G
Sbjct: 1140 ICSARVTLREPPSFIKKIESTSSLRG 1165



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 4/82 (4%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG-- 718
            E  G P  +I W K+   + +  ++ +  +   +SL +L     D+GEY CR  +  G  
Sbjct: 1080 EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 1139

Query: 719  VAETKAVLHVTPR--ATIERTS 738
            +   +  L   P     IE TS
Sbjct: 1140 ICSARVTLREPPSFIKKIESTS 1161



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/114 (22%), Positives = 57/114 (50%), Gaps = 4/114 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  IT+ ++ +++ ++G     +V+     ++  +W+++G+ L  G +Y+         L
Sbjct: 1243 PATITE-EAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSIL 1301

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEAL 3943
             I+    +DSGEY     ND G    KA I+   + D+I+     + +K+ +++
Sbjct: 1302 KIISTEKKDSGEYTFEVQNDVGRSSCKARIN---VLDLIIPPSFTKKLKKMDSI 1352



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 3/106 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F + L     + +G  I LEC +   G   + ++WF + + ++   ++K  +      
Sbjct: 1340 PSFTKKLKKMDSI-KGSFIDLECIVA--GSHPISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
            L+I      D+G YT  A N  G    S  + V E    V   Q++
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQ 1442



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 18/79 (22%), Positives = 37/79 (46%)

Query: 1725 NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYT 1784
            N     + + +  G   + ++W ++   + +    +   D    +L +      DSGTY 
Sbjct: 1445 NPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYI 1504

Query: 1785 CRAINELGEAVTSSTLFVQ 1803
            C+  N++G A + +TLFV+
Sbjct: 1505 CQLSNDVGTATSKATLFVK 1523



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 18/63 (28%), Positives = 33/63 (52%)

Query: 1607 ATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666
            A + ++W+ +NK L SG+  +   +    +L++ +    DSGTY C+  N +G A +   
Sbjct: 1460 APMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKAT 1519

Query: 1667 AIV 1669
              V
Sbjct: 1520 LFV 1522



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/69 (28%), Positives = 32/69 (46%)

Query: 1876 MRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLN 1935
            M ++W+ + K L SG       D    +L++      DSG Y C+  N++G A S   L 
Sbjct: 1462 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 1521

Query: 1936 VQSKESIIR 1944
            V+     I+
Sbjct: 1522 VKEPPQFIK 1530



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 5/105 (4%)

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
            SIE +  + P FIR L+ + E+ +  +   E ++T    P   V W K+ R I +S + T
Sbjct: 1611 SIELKVKEPPTFIRELKPV-EVVKYSDVELECEVT--GTPPFEVTWLKNNREIRSSKKYT 1667

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
                    +L+I      D G Y     N+ G    + S RVA +
Sbjct: 1668 LTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSC--SCSTRVALK 1710



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/108 (22%), Positives = 46/108 (42%), Gaps = 2/108 (1%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P FT  +  +      + H E ++   G   +  +W ++G  I  S +   +     V+L
Sbjct: 1902 PSFTKKLTKMDKVLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSL 1959

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
             +  +  ED+  YTC+  N  G+   S  L V+   S  ++   + A+
Sbjct: 1960 EVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAI 2007



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 4/130 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F+ +   Q ++ +  T +F+  L   G P  K++WF +   L+   +     +  
Sbjct: 1992 KEPPSFLVKPGRQQAIPD-STVEFKAILK--GTPPFKIKWFKDDVELVSGPKCFIGLEGS 2048

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE 4089
               +N   V    +G+Y C  TN  G D    ++  T  P  V   +  K +K+ +  R 
Sbjct: 2049 TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSR- 2107

Query: 4090 MEASWQVTPE 4099
            +E     +PE
Sbjct: 2108 LECKIAGSPE 2117



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2791 IHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKA 2850
            +  EC  E S  P  ++ W+ + + L S  +YK      + S+ I +    D G Y CKA
Sbjct: 2199 VSLEC--ELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKA 2256

Query: 2851 TNSKGSAT 2858
             N  GS T
Sbjct: 2257 QNEVGSDT 2264



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 19/53 (35%), Positives = 29/53 (54%)

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
            P   V WY + + L+S  +Y+ ++     ++ IL V   D GEY CKA N +G
Sbjct: 2209 PPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 2261



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/61 (36%), Positives = 33/61 (54%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L VEW KDG+ + +S +    F     +L I SV   DAG YT +  N +G+++ +
Sbjct: 2394 GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCT 2453

Query: 997  A 997
            A
Sbjct: 2454 A 2454



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 2/112 (1%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V+V+    P   T+    T    G S   EC++       + V W+     + SG +Y+T
Sbjct: 2456 VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAG--SSPISVAWFHEKTKIVSGAKYQT 2513

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            +       L + ++   D G YTC A N  G       L VQ   S +++ +
Sbjct: 2514 TFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPE 2565



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 1586 NVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPE 1645
            ++++  G+ A FE  +       +++ W  +NK ++ G  +T T       L I+     
Sbjct: 2944 SIDVIAGESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKG 3001

Query: 1646 DSGTYTCRAINALGEAVTS 1664
            DSG YTC+A N +G+ + S
Sbjct: 3002 DSGQYTCQATNDVGKDMCS 3020



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 3/98 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P FI +L     +  G S   ECR+       + V W+ +G  + SG + ++S       
Sbjct: 3406 PSFIRKLKDVNAIL-GASVVLECRVSG--SAPISVGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            L++  +   D+G YTC A N  G    S  L VQ   S
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPS 3500



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G++  F+C+V  +    +KI W  +N+ +  G  YK T   +  +L +    + D+G YT
Sbjct: 3891 GESGTFKCHVTGTAP--IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYT 3948

Query: 2848 CKATNSKGSATTSGSL 2863
            C A+N  G  + S  L
Sbjct: 3949 CYASNIAGKDSCSAQL 3964



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 5/107 (4%)

Query: 3546 DTLTPEAESGNPPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTG 3603
            D+ + +     PP F     PS ++  ++    +EC++       ++V W+ +   +   
Sbjct: 3958 DSCSAQLGVQEPPRFIKKLEPSRIV-KQDEFTRYECKI--GGSPEIKVLWYKDETEIQES 4014

Query: 3604 SRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            S+ +        +LE+  +   D+G YTC+A N  G A+ S  L+VK
Sbjct: 4015 SKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 4061



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 4/77 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P + R LQD+  L+EG+      Q    S P ++ EW+++GR +    R  +        
Sbjct: 5410 PAWERHLQDV-TLKEGQTCTMTVQF---SVPNVKSEWFRNGRILKPQGRHKTEVEHKVHK 5465

Query: 830  LNIMHLRAEDAGSYTVR 846
            L I  +RAED G YT +
Sbjct: 5466 LTIADVRAEDQGQYTCK 5482



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++P  FTK++Q   V EH+ A FE E   +   ++ WY+    +  S  +          
Sbjct: 5496 AEPIQFTKRIQNIVVSEHQSATFECEVSFDD-AIVTWYKGPTELTESQKYNFRNDGRCHY 5554

Query: 4468 LIIRQVFVEDSAVFAAVAE-NRGGTAKCSANLVVEEK 4503
            + I  V  +D  V++ +A     G A+ +A L +  K
Sbjct: 5555 MTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTK 5591



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F T P    +   S+   +        + + + WF   K L++G       +     
Sbjct: 870  PPSFVTKPGSKDVLPGSAVCLKSTF--QGSTPLTIRWFKGNKELVSGGSCYITKEALESS 927

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            LE+  V   D+G YTCK +N  G    S  L VK
Sbjct: 928  LELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 961



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/116 (22%), Positives = 50/116 (43%), Gaps = 3/116 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI +I+S +        F+  +  K    + + W ++   +      R  ++    S
Sbjct: 1150 PPSFIKKIESTSSLRGGTAAFQATL--KGSLPITVTWLKDSDEITEDDNIRMTFENNVAS 1207

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            L +  +  +  G+Y+C+A ND G     A +S K+ P  I +  V   + + +  T
Sbjct: 1208 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE-PATITEEAVSIDVTQGDPAT 1262



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 2/86 (2%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F +    +  ++ GQ+  F+C++   G P ++V W+ +   I    +   +   G
Sbjct: 1523 KEPPQFIKKPSPVLVLRNGQSTTFECQI--TGTPKIRVSWYLDGNEITAIQKHGISFIDG 1580

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
              +  IS  R E+ G Y+C A N  G
Sbjct: 1581 LATFQISGARVENSGTYVCEARNDAG 1606



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/125 (21%), Positives = 54/125 (43%), Gaps = 3/125 (2%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F+ +           V F+  +  K  P  +I+W+++   L SG +     +  
Sbjct: 1991 VKEPPSFLVKPGRQQAIPDSTVEFKAIL--KGTPPFKIKWFKDDVELVSGPKCFIGLEGS 2048

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945
               L++  V A  +G+Y C   ND G D     +   + P  + + +  + +K  ++ ++
Sbjct: 2049 TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDS-SR 2107

Query: 3946 MEATI 3950
            +E  I
Sbjct: 2108 LECKI 2112



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F      V  ++  ++  E  +   G P  ++ W K+ + + +S ++    +  
Sbjct: 2178 VKEPPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNF 2235

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATG 718
            + S+ +L+++  D GEY C+A +  G
Sbjct: 2236 HTSIHILNVDTSDIGEYHCKAQNEVG 2261



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 18/77 (23%), Positives = 36/77 (46%)

Query: 786  RNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTV 845
            +NA    +      P   V WYKD R + +S +        + S++I+++   D G Y  
Sbjct: 2195 KNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHC 2254

Query: 846  RAVNKLGEAISTASIRV 862
            +A N++G      ++++
Sbjct: 2255 KAQNEVGSDTCVCTVKL 2271



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 2130 ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNK 2189
            EC+V   + P +++ WFH   KI +G +Y+TT       L +    + D G Y C A N 
Sbjct: 2485 ECKVAG-SSP-ISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANV 2542

Query: 2190 LG 2191
             G
Sbjct: 2543 AG 2544



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 20/76 (26%), Positives = 33/76 (43%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G S + V W  +   + + ++  T F+     L + S+   D G+YTC A N  G     
Sbjct: 2490 GSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECR 2549

Query: 997  ANLTIVTKKDIIAESQ 1012
            A LT+      + E +
Sbjct: 2550 AVLTVQEPPSFVKEPE 2565



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 2/94 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   P  L +    +  F    +       +V WF   + L+ G R     +     
Sbjct: 2557 PPSFVKEPEPLEVLPGKNVTFTS--VIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 2614

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            LE+  +    +G YTC  +N  G+A+ + +L VK
Sbjct: 2615 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVK 2648



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 5/128 (3%)

Query: 1402 VIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTI--KPRFVTRPKSIENVIEG 1459
            V  +K  ILE  + +  +  QY  +       D+    V+    P FVT  + +E  + G
Sbjct: 2700 VTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAV-G 2758

Query: 1460 QHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTC 1519
              V  +C++    +  + V W+K    +     +R         L    +   DSG YTC
Sbjct: 2759 DSVSLQCQVAGTPE--ITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTC 2816

Query: 1520 RAVNLVGT 1527
            +A N +GT
Sbjct: 2817 KAENSIGT 2824



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G +A FE  +T      MR+ W KD + I      T         L I+ +   D+G YT
Sbjct: 2950 GESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYT 3007

Query: 845  VRAVNKLGEAISTASIRV 862
             +A N +G+ + +A + V
Sbjct: 3008 CQATNDVGKDMCSAQLSV 3025



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P+F +    I+ ++ G   H +C L   G P   V W+++++ +    +     +  
Sbjct: 4061 KEPPIFRKKPHPIETLK-GADVHLECEL--QGTPPFHVSWYKDKRELRSGKKYKIMSENF 4117

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
              S+ I +V   D G Y C+A+N +G
Sbjct: 4118 LTSIHILNVDAADIGEYQCKATNDVG 4143



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 4/104 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFN-GKPLLHKNRFTPIYDF 4028
            K PPRFV ++   +++V  E    + Q    G   + V WF + G+ +   +     Y  
Sbjct: 4154 KAPPRFVKKLSDISTVVGKEV---QLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSE 4210

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                + F  V P ++G+Y C+  N  GM E  A +       IV
Sbjct: 4211 NIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV 4254



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/66 (36%), Positives = 30/66 (45%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   + V W K+G  V  S R           L I S TV DAG Y C   NA G+ + S
Sbjct: 4558 GTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIENASGKDSCS 4617

Query: 997  ANLTIV 1002
            A + I+
Sbjct: 4618 AQILIL 4623



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F+  ++D++        F+  +   G   + V W ++G P++ S  + T        L
Sbjct: 4722 PSFSRQLRDVQETVGLPVVFDCAIS--GSEPISVSWYKDGKPLKDSPNVQTSFLDNTATL 4779

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            N+   +   +G Y+C A N +G A +S+ L +
Sbjct: 4780 NIFKTDRSLAGQYSCTATNPIGSASSSARLIL 4811



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG++   E  V  S+  T  + W+ NN  +   +  + T   + + L +      D+G+Y
Sbjct: 4928 EGNSFKLEGRVAGSQPIT--VAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLY 4985

Query: 2847 TCKATNSKGSATTSGSL 2863
            TCK +N  GSA  + S+
Sbjct: 4986 TCKVSNDAGSALCTSSI 5002



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 34/148 (22%), Positives = 59/148 (39%), Gaps = 10/148 (6%)

Query: 4622 PPEIIEPLKDKIVAE----GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
            P + ++ +KD I+ E    G +  F C +V        W K    I+ S   +      +
Sbjct: 7801 PLKFVKEIKDIILTESEFVGSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRFIADGKD 7859

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
              L I +    D G+Y CV        T  AKL V   ++       T   ++ V +GQP
Sbjct: 7860 RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV---EELPVRFVKTLEEEVTVVKGQP 7916

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETP 4765
                 ++    +  + W ++G ++ E P
Sbjct: 7917 LYLSCELNK--ERDVVWRKDGKIVVEKP 7942



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/118 (23%), Positives = 45/118 (38%), Gaps = 2/118 (1%)

Query: 3541 YSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL 3600
            Y     T T       PP F + P  L      +A F C +       +   W  +G  L
Sbjct: 199  YGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTV--TGTPVIETIWQKDGAAL 256

Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILE 3658
                  +  +     ILE+  +  +D G+Y+CKA+N+ G      +L +  +   I E
Sbjct: 257  SPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKE 314



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 4/69 (5%)

Query: 1591 EGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTY 1650
            E  R H + +  PV    ++V W+ NNK L   +            LDI     EDSG+Y
Sbjct: 418  ESARLHCKLKGSPV----IQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSY 473

Query: 1651 TCRAINALG 1659
            +C A+N +G
Sbjct: 474  SCEAVNDVG 482



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 2/110 (1%)

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQG 2957
            G + SV +    +P  II  A   Q+  G    LE  V     P+LK +WY +G+ L   
Sbjct: 668  GSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVA--GTPELKPKWYKDGRPLVAS 725

Query: 2958 SRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
             +++++       L        DSG YT +  N+ G +   +T     +D
Sbjct: 726  KKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRD 775



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 2/101 (1%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
           V  PP F+    S   + G  +  ++  +  G   + I W K  + + +           
Sbjct: 867 VQEPPSFVTKPGSKDVLPGSAVCLKSTFQ--GSTPLTIRWFKGNKELVSGGSCYITKEAL 924

Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             SL++  +   DSG YTC+  +  G  E  A L V   AT
Sbjct: 925 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPAT 965



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/72 (31%), Positives = 35/72 (48%)

Query: 2665 QVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724
            QV+      +  +WFK+G  LT G++ K +    +  L I S    DSG YT +  N +G
Sbjct: 1264 QVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVG 1323

Query: 2725 EAVSTASIKIED 2736
             +   A I + D
Sbjct: 1324 RSSCKARINVLD 1335



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/114 (21%), Positives = 51/114 (44%), Gaps = 2/114 (1%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F   +++       +A F++ +   G P + + WL++   ++  + +       
Sbjct: 1709 LKEPPSFIKKIENTTTVLKSSATFQSTV--AGSPPISITWLKDDQILDEDDNVYISFVDS 1766

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
               L ++ V+   SG YTC+A NE G     + L VQ  A +  +++     +K
Sbjct: 1767 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEK 1820



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 77/395 (19%), Positives = 143/395 (36%), Gaps = 30/395 (7%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P F++ + N   V +        +    G P + + W  + + +         +   
Sbjct: 1710 KEPPSFIKKIENTTTVLKSSATF---QSTVAGSPPISITWLKDDQILDEDDNVYISFVDS 1766

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQL-LE 1292
               L I    +  +G YT +A N  G     A + V E + IV   ++    E+  + LE
Sbjct: 1767 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLE 1826

Query: 1293 DAARRT-----KQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVE-- 1345
                 T     K +++   ++ +  FS +  N   V    +    + Q  G  T +VE  
Sbjct: 1827 CVVAGTPELKVKWLKDGKQIVPSRYFSMSFEN--NVASFRIQSVMK-QDSGQYTFKVEND 1883

Query: 1346 ---WFCNGKPIKTGHRFRPAYEFDYVALDLL---SVYPE----DSGVYTCQATNQLGEAV 1395
                 C+           P++      +D +   S++ E     S   + Q      E  
Sbjct: 1884 FGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIS 1943

Query: 1396 TSCALRVIA-KKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIK--PRFVTRPKS 1452
            TS   R++  ++ + LE  +    +   Y    S     D     +T+K  P F+ +P  
Sbjct: 1944 TSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGR 2003

Query: 1453 IENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
             +  I    V F+  L+       K++WFK+   +  G +     +     L++  + A 
Sbjct: 2004 -QQAIPDSTVEFKAILKGTPP--FKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDAS 2060

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
             +G YTC   N VG+D  +  L        V+  +
Sbjct: 2061 KTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLE 2095



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 2/86 (2%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            +  P  + E   +  V E      EC V     P L++++  +GK +  +  F ++F+  
Sbjct: 1802 VQEPAQIVEKAKSVDVTEKDPMTLECVVAGT--PELKVKWLKDGKQIVPSRYFSMSFENN 1859

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALG 2324
              S  IQ  + +D+G+Y+ K  N  G
Sbjct: 1860 VASFRIQSVMKQDSGQYTFKVENDFG 1885



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/96 (20%), Positives = 45/96 (46%), Gaps = 2/96 (2%)

Query: 767  SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG 826
            ++ P+F++ L+    ++ G ++  E ++     P +RV W+++   + AS +    F   
Sbjct: 2085 TEPPKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDS 2142

Query: 827  YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               + + +L  ED+G +   A N  G    +  + V
Sbjct: 2143 VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIV 2178



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 11/145 (7%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F +      +L   E +  EC+L+  G P  +V W+ + + L    ++       
Sbjct: 2179 KEPPVFSSFPPIVETLKNAEVS-LECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKNF 2235

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD-------SQLPKHMK 4082
            + +++   V   D GEY C+A N  G D     +K    P  V         +  P  ++
Sbjct: 2236 HTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQ 2295

Query: 4083 -SIEKIREMEASWQVTPEQVVEESK 4106
             SIE  + +   W    E+V+ ES+
Sbjct: 2296 ASIEGAQPIFVQWLKEKEEVIRESE 2320



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/117 (21%), Positives = 52/117 (44%), Gaps = 4/117 (3%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTVYDMGFV 3887
            PP+F++++ S TV   E    +  +E  +   + ++W +   +++      R  +     
Sbjct: 2274 PPRFVSKLNSLTVVAGEPAELQASIEGAQ--PIFVQWLKEKEEVIRESENIRITFVENVA 2331

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            +L        ++G+YIC+  ND G     AT+   + P +I++   P  +   E  T
Sbjct: 2332 TLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLE-PAVIVEKAGPMTVTVGETCT 2387



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            GE    E ++  T  P L VEWY +GK L +  + +         L I     +D+G Y 
Sbjct: 2383 GETCTLECKVAGT--PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 2440

Query: 3495 CRAYNNYGEAVTTASMKVQGK 3515
             +  NN G++  TA + V  +
Sbjct: 2441 FQVQNNVGKSSCTAVVDVSDR 2461



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 3/109 (2%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F    + + V   +   F +  +  G P  +V W R    +   +R     +  
Sbjct: 2554 VQEPPSFVKEPEPLEVLPGKNVTFTS--VIRGTPPFKVNWFRGARELVKGDRCNIYFEDT 2611

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS-LQLESQH 1814
               L +  ++   SG YTC   N  G+A  ++ LFV+  A+ L+  S H
Sbjct: 2612 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDH 2660



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 3/91 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P FV  P+ +E V+ G++V F   +        KV WF+  + +  G R     +     
Sbjct: 2558 PSFVKEPEPLE-VLPGKNVTFTSVIRGTPP--FKVNWFRGARELVKGDRCNIYFEDTVAE 2614

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L++ ++    SG YTC   N  G    + RL
Sbjct: 2615 LELFNIDISQSGEYTCVVSNNAGQASCTTRL 2645



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/98 (22%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            +E P F   ++  E   G  V L+  +     P + V WY     ++    ++T +    
Sbjct: 2741 LEPPYFVTELEPLEAAVGDSVSLQCQVA--GTPEITVSWYKGDTKLRPTPEYRTYFTNNV 2798

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
              L        D+G Y CKA N++G A + +  ++  +
Sbjct: 2799 ATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 2836



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +KDI            RL   G   ++V W R+GV +     L T        L
Sbjct: 2840 PSFARQLKDIEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDHENLQTSFVDNVATL 2897

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
             +   +   SG Y+C A N LG A +S+ L
Sbjct: 2898 KILQTDLSHSGQYSCSASNPLGTASSSARL 2927



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F +   S+  + G    FE  +   G   M+I W K+ + I     +T         L
Sbjct: 2936 PFFDIKPVSIDVIAGESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHL 2993

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +L +   DSG+YTC+A +  G     A L V
Sbjct: 2994 RILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 3025



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)

Query: 3294 LVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSG 3353
            ++ G+SA FE  +       +++ W  + K++  G  Y          L IL   + +SG
Sbjct: 2947 VIAGESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSG 3004

Query: 3354 EYECVATNKLGRDSTKANL 3372
            +Y C ATN +G+D   A L
Sbjct: 3005 QYTCQATNDVGKDMCSAQL 3023



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/85 (28%), Positives = 32/85 (37%), Gaps = 2/85 (2%)

Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGF 1634
            T  P  T  LK      G     E ++       + V W+H    + SG ++  T     
Sbjct: 4344 TVPPSFTRKLKETNGLSGSSVVMECKVY--GSPPISVSWFHEGNEISSGRKYQTTLTDNT 4401

Query: 1635 VALDIMSCLPEDSGTYTCRAINALG 1659
             AL +      DSG YTC A N  G
Sbjct: 4402 CALTVNMLEESDSGDYTCIATNMAG 4426



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 2504 EFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF 2563
            E + P F  +   P +   G+ A +E  V   G   ++  W  +  E++ G +++ ++  
Sbjct: 4813 EGKNPPFFDIRLAPVDAVVGESADFECHVT--GTQPIKVSWAKDSREIRSGGKYQISYLE 4870

Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590
                L +  V   D+G Y C A+N  G
Sbjct: 4871 NSAHLTVLKVDKGDSGQYTCYAVNEVG 4897



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 39/156 (25%), Positives = 60/156 (38%), Gaps = 9/156 (5%)

Query: 1056 VEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGV 1115
            V G+SA FE  V     +   V W  + ++I S  + Q  +      L +  V   DSG 
Sbjct: 4830 VVGESADFECHVTGTQPIK--VSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQ 4887

Query: 1116 YTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF-----VEPMYQIE 1170
            YT  A N  G+   +A + ++ R  +   S  + L E     E + F     V     I 
Sbjct: 4888 YTCYAVNEVGKDSCTAQLNIKER--LIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPIT 4945

Query: 1171 EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGD 1206
                   + +QP SN     +   + L+ R   M D
Sbjct: 4946 VAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMND 4981



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 7/125 (5%)

Query: 1933 RLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRA----VQDDSFVVEKPQFGKPIKNAE 1988
            +L    K  I  D    +   K   L+D   Y+      +      V +P + + +++  
Sbjct: 5361 KLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVT 5420

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            + EG    +    +    P ++ EW+ NGR ++   R KT  +     L I    AED G
Sbjct: 5421 LKEGQTCTMTVQFSV---PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQG 5477

Query: 2049 TYMCK 2053
             Y CK
Sbjct: 5478 QYTCK 5482



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 7/110 (6%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            L+EG      VQ S  P  +  WF+NG+ L    +H+    H    L + + +  D G Y
Sbjct: 5421 LKEGQTCTMTVQFSV-PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQY 5479

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
            T   E+    + TS  L +E+    +   +R Q I  ++ +      E+S
Sbjct: 5480 TCKYED----LETSAELRIEAEPIQFT--KRIQNIVVSEHQSATFECEVS 5523



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 7/126 (5%)

Query: 1689 NQLEDTSKYQRHSAQDEVITQA-PV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            +Q + T KY+      E+  +A P+ FT  +++I V+E+Q+A FE     V      V W
Sbjct: 5475 DQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECE---VSFDDAIVTW 5531

Query: 1747 LRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRA-INELGEAVTSSTLFVQSK 1805
             +    +  S +    +D     + +  V P+D G Y+  A +   GEA +++ L++ +K
Sbjct: 5532 YKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTK 5591

Query: 1806 ASLQLE 1811
              ++LE
Sbjct: 5592 -EIKLE 5596



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 2/74 (2%)

Query: 928  HFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAY 987
            H E +++   D  + V W KDG+ +         F      L I    + D+G Y C A 
Sbjct: 327  HLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTAS 384

Query: 988  NAIGQATTSANLTI 1001
            N  G ++ SA +T+
Sbjct: 385  NEAGSSSCSATVTV 398



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F + +     +  G+ A    ++   G P ++  W+ N  EL   +  R       
Sbjct: 400  EPPSFVKKVDPSYLMLPGESARLHCKLK--GSPVIQVTWFKNNKELSESNTVRMYFVNSE 457

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
              LDI  V   D+G Y C+A+N  G
Sbjct: 458  AILDITDVKVEDSGSYSCEAVNDVG 482



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 15/59 (25%), Positives = 33/59 (55%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            +++ W+ +GK +    R+++    G  +L+++ V   D+G +TC+A N  G   +S  +
Sbjct: 807  MRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL 865



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 3/117 (2%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            VA+ + P FI ++   T + +  SA ++  +     P + + W  + ++L        S 
Sbjct: 1707 VALKEPPSFIKKIENTTTVLKS-SATFQSTVAG--SPPISITWLKDDQILDEDDNVYISF 1763

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
                A L I +V    SG YTC+A N  G       L VQ    I+  ++     EK
Sbjct: 1764 VDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEK 1820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 3/113 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F   I++  ++ +   A F++ +   G   + + WLKD + ++    +   F    
Sbjct: 1711 EPPSFIKKIENTTTVLKSS-ATFQSTVA--GSPPISITWLKDDQILDEDDNVYISFVDSV 1767

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEK 1019
              L I+SV    +G YTC+A N  G     A L +     I+ +++     EK
Sbjct: 1768 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEK 1820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query: 4110 PPVFVS-LPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            PP FV  L  +  V+ G+ +R  C++ G P+ RV+W  N + +    +Y++T+
Sbjct: 2087 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF 2139



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            + E    P  ++ WY + + L    ++K+ S     ++ +++V   D G Y CKA N+ G
Sbjct: 2202 ECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 2261

Query: 2994 EAFTSSTVYCTSK 3006
                S T  CT K
Sbjct: 2262 ----SDTCVCTVK 2270



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 2/71 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+    EC V  +  P L +EW+ + K L S  ++K +      SL I     +D+G YT
Sbjct: 2383 GETCTLECKVAGT--PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 2440

Query: 2848 CKATNSKGSAT 2858
             +  N+ G ++
Sbjct: 2441 FQVQNNVGKSS 2451



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 17/55 (30%), Positives = 29/55 (52%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G   +   W+    ++  G++++TT      TL +NS+ ++D G Y C A N AG
Sbjct: 2490 GSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAG 2544



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 3/93 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F++  + L E+  G+N  F + +     P  +V W++  R +    R    F      
Sbjct: 2558 PSFVKEPEPL-EVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 2614

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            L + ++    +G YT    N  G+A  T  + V
Sbjct: 2615 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 2647



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 2/79 (2%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            G+N  F + +  T  P  KV W+   + L  G R   + +     LE+       SGEY 
Sbjct: 2572 GKNVTFTSVIRGT--PPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 2629

Query: 3495 CRAYNNYGEAVTTASMKVQ 3513
            C   NN G+A  T  + V+
Sbjct: 2630 CVVSNNAGQASCTTRLFVK 2648



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            + P R + +    T V  G     EC V     P L  +++ +G+ L + ++ HITF   
Sbjct: 3307 LEPARIIEKPEPMT-VTTGNPFALECVVTGT--PELSAKWFKDGRELSADSKHHITFINK 3363

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
              SL I      D G YS +  N++G     +S+ V+
Sbjct: 3364 VASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVS 3400



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ 1093
            E  V + + P F+ PL+    ++ G+ A  + +V+   ++   + WY    ++ SA   +
Sbjct: 3676 EALVSVLEPPYFIEPLEHVEAVI-GEPATLQCKVDGTPEIR--ISWYKEHTKLRSAPAYK 3732

Query: 1094 TYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
                    +L I  V   D G Y+  A N+ G    SA + ++ R
Sbjct: 3733 MQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR 3777



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP FI  ++ V  ++ G+ A  + ++     P++++ W+    KL     Y+      +
Sbjct: 3683 EPPYFIEPLEHVEAVI-GEPATLQCKVDGT--PEIRISWYKEHTKLRSAPAYKMQFKNNV 3739

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L I      + GEY C A N +G  ++ A L
Sbjct: 3740 ASLVINKVDHSDVGEYSCKADNSVGAVASSAVL 3772



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 1/87 (1%)

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            +++ W  + R ++ G  +K T       L +L     D G Y C A+N  G+   ++ + 
Sbjct: 3906 IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLG 3965

Query: 2069 VDAKSGLYLDTLDEQRLKKIQELEKYE 2095
            V  +   ++  L+  R+ K  E  +YE
Sbjct: 3966 VQ-EPPRFIKKLEPSRIVKQDEFTRYE 3991



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 3/94 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P FT  L     L  G +   E ++  +  P + V W+  G  + +G +++T        
Sbjct: 4347 PSFTRKLKETNGL-SGSSVVMECKVYGS--PPISVSWFHEGNEISSGRKYQTTLTDNTCA 4403

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            L ++     DSG+Y C A N  G    +A + V+
Sbjct: 4404 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVR 4437



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P     L  V+   G+ A FE  +       +KV W  +++ ++SG ++  +       L
Sbjct: 4818 PFFDIRLAPVDAVVGESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHL 4875

Query: 1638 DIMSCLPEDSGTYTCRAINALGE 1660
             ++     DSG YTC A+N +G+
Sbjct: 4876 TVLKVDKGDSGQYTCYAVNEVGK 4898



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 4/76 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P +   +QDVT L EGQ+       V    P++K EWF NG+ L    R++T  +  +  
Sbjct: 5410 PAWERHLQDVT-LKEGQTC---TMTVQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHK 5465

Query: 3342 LDILYCYEENSGEYEC 3357
            L I     E+ G+Y C
Sbjct: 5466 LTIADVRAEDQGQYTC 5481



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 5/89 (5%)

Query: 4727 LRDIVVYE----GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782
            ++DI++ E    G  A F+  ++     T  W+++G+ I E+P  + I +G +  L I +
Sbjct: 7808 IKDIILTESEFVGSSAIFECLVSPSTAITT-WMKDGSNIRESPKHRFIADGKDRKLHIID 7866

Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                D G +TC       +  ++AKLVV+
Sbjct: 7867 VQLSDAGEYTCVLRLGNKEKTSTAKLVVE 7895



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 16/51 (31%), Positives = 28/51 (54%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            PP F+S P ++T   G+ A+F C VTG P    +W  +G  +     ++++
Sbjct: 215  PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRIS 265



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 19/66 (28%), Positives = 32/66 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P LK +W+K+G  L    + + +F   +  L   S    DSG YT + +N +G +    +
Sbjct: 709  PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 768

Query: 2732 IKIEDR 2737
              + DR
Sbjct: 769  FTVLDR 774



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/83 (25%), Positives = 35/83 (42%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G   L + W +    + +        +    +L +  V   DSGTYTC+  N  G    S
Sbjct: 896  GSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECS 955

Query: 1798 STLFVQSKASLQLESQHESALQK 1820
            + LFV+  A+   + +    L+K
Sbjct: 956  ANLFVKEPATFVEKLEPSQLLKK 978



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/66 (31%), Positives = 30/66 (45%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P +++ W  N   I+ S++           L +  V  EDSG Y C A NE G    S
Sbjct: 990  GTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS 1049

Query: 1798 STLFVQ 1803
            S + V+
Sbjct: 1050 SIVIVK 1055



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 7/131 (5%)

Query: 1538 STTDIVRSTQNEAGLEQIQVLED--RSKYH-RTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
            S   I+ + + ++G    +V  D  RS    R +++D +    P  T  LK ++  +G  
Sbjct: 1299 SILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIP--PSFTKKLKKMDSIKGSF 1356

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
               E   I      + ++W+ +++ + +  ++  + +     L+I      DSGTYTC A
Sbjct: 1357 IDLE--CIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSA 1414

Query: 1655 INALGEAVTSG 1665
             N  G    SG
Sbjct: 1415 TNKAGHNQCSG 1425



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F + L+ ++ ++       +C +   G P  +V W +N + I  S + T T    
Sbjct: 1617 KEPPTFIRELKPVEVVKYSDV-ELECEV--TGTPPFEVTWLKNNREIRSSKKYTLTDRVS 1673

Query: 2433 YVSMTISHVRDEDEGVYMCRASN 2455
              ++ I+     D G Y C  SN
Sbjct: 1674 VFNLHITKCDPSDTGEYQCIVSN 1696



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G+T   +C++   G P L VEW+++ KL+  S +   +      S+ I  V  +D G Y 
Sbjct: 2383 GETCTLECKV--AGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYT 2440

Query: 2451 CRASNLLGE 2459
             +  N +G+
Sbjct: 2441 FQVQNNVGK 2449



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            + P F  + K IE  + G  V   C+L     + ++V W+++G  +      +       
Sbjct: 2838 LPPSFARQLKDIEQTV-GLPVTLTCRLNG--SAPIQVCWYRDGVLLRDHENLQTSFVDNV 2894

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
              L I+      SG Y+C A N +GT   S RLT R
Sbjct: 2895 ATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 2930



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F   LK +    G  +    R+   G   +++ W ++G  +       + F     +
Sbjct: 2839 PPSFARQLKDIEQTVGLPVTLTCRLN--GSAPIQVCWYRDGVLLRDHENLQTSFVDNVAT 2896

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVL 726
            L +L  ++  SG+Y+C A +  G A + A L
Sbjct: 2897 LKILQTDLSHSGQYSCSASNPLGTASSSARL 2927



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 5/115 (4%)

Query: 1174 KSKPVF-VQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            K  P F ++P+S    V  G++   EC +   G   MR+ W  + + +  G  +      
Sbjct: 2933 KKSPFFDIKPVSID--VIAGESADFECHVT--GAQPMRITWSKDNKEIRPGGNYTITCVG 2988

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQ 1287
                L I+     D+G+YT +A N +G    SA + V E    V   +  +  +Q
Sbjct: 2989 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQ 3043



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F +    +G L+ G +   + +++    P   V W KD + +  S +          +
Sbjct: 3123 PVFTQKPSPVGALK-GSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTN 3179

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIR 861
            L+I++L A D G Y  +A N++G    + S++
Sbjct: 3180 LHILNLEASDVGEYHCKATNEVGSDTCSCSVK 3211



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/98 (21%), Positives = 46/98 (46%), Gaps = 2/98 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + P     L++VE   G+ A  + ++    +  +++ WY  +  L+S   +         
Sbjct: 3683 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPE--IRISWYKEHTKLRSAPAYKMQFKNNVA 3740

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
            +L I      D G Y+C+A N++G   +S + ++ ++K
Sbjct: 3741 SLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK 3778



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/55 (32%), Positives = 25/55 (45%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P +R  WY    +L+    ++        +L IN V  +D G Y CKA N  G
Sbjct: 3710 GTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVG 3764



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P F + L +      G  +  ECR+   G   ++V W+ +G  +   +  +T +   
Sbjct: 3778 KLPPFFARKLKDVHETL-GFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHN 3834

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
               L I+    +  G+Y   A N LG+A +SA
Sbjct: 3835 VATLQILQTDQSHIGQYNCSASNPLGTASSSA 3866



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSS-MRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F     D+  +      FECR   +N S  ++V W+ +G  L   + ++T       
Sbjct: 3780 PPFFARKLKDVHETLGFPVAFECR---INGSEPLQVSWYKDGVLLKDDANLQTSFVHNVA 3836

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
             L+I    Q   G Y C A+N  G A+ S KL
Sbjct: 3837 TLQILQTDQSHIGQYNCSASNPLGTASSSAKL 3868



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 19/86 (22%), Positives = 37/86 (43%), Gaps = 2/86 (2%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P+F      I   +    H E  L   G P   V W ++   + +  +   M +  
Sbjct: 4060 VKEPPIFRKKPHPIETLKGADVHLECEL--QGTPPFHVSWYKDKRELRSGKKYKIMSENF 4117

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELG 1792
              ++++  V+  D G Y C+A N++G
Sbjct: 4118 LTSIHILNVDAADIGEYQCKATNDVG 4143



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 2/83 (2%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            I   +G   H E  L+  G     V W KD R + +  +          ++ I +V   D
Sbjct: 4073 IETLKGADVHLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAAD 4130

Query: 979  AGHYTCRAYNAIGQATTSANLTI 1001
             G Y C+A N +G  T   ++ +
Sbjct: 4131 IGEYQCKATNDVGSDTCVGSIAL 4153



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/96 (23%), Positives = 39/96 (40%), Gaps = 2/96 (2%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P  + +      +   +T   EC +A  G P +  +WF +GK L   N++   +      
Sbjct: 4250 PATIVEKPESIKVTTGDTCTLECTVA--GTPELSTKWFKDGKELTSDNKYKISFFNKVSG 4307

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
            +    V P DSG Y     N  G D   A ++ + +
Sbjct: 4308 LKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 4343



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 4105 SKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DG 4163
            ++ + PP F      V    GE A F C VTG    +V W  +   I +G +Y+++Y + 
Sbjct: 4812 TEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN 4871

Query: 4164 MYHFDIPKTRQYDTGK 4179
              H  + K  + D+G+
Sbjct: 4872 SAHLTVLKVDKGDSGQ 4887



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S+P +R++W K GR I  S R +  F  G   L +  +   D+G Y  +A N  G   + 
Sbjct: 5037 SEP-IRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTK 5095

Query: 858  ASIRVAARSTV 868
            + + +  +  V
Sbjct: 5096 SKVTIKDKPAV 5106



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 9/126 (7%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G SA +EC + P         W  +G  ++   ++R   D     L I+ V   D+GEYT
Sbjct: 7820 GSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 7876

Query: 1919 CKAINNLGQAVSSIRLNVQS-KESIIRDSQHESALEKIQ--YLEDDSRYKRAV---QDDS 1972
            C       +  S+ +L V+      ++  + E  + K Q  YL  +   +R V   +D  
Sbjct: 7877 CVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGK 7936

Query: 1973 FVVEKP 1978
             VVEKP
Sbjct: 7937 IVVEKP 7942



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/72 (29%), Positives = 32/72 (44%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            L I W+   K L  G    +T +    +L+L  V   DSG YTCK  N  G    S+ ++
Sbjct: 900  LTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLF 959

Query: 3003 CTSKDNLIERTQ 3014
                   +E+ +
Sbjct: 960  VKEPATFVEKLE 971



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 4/92 (4%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            P  FV +L  +  + +G      C+V     P ++I ++ N + ++ +++  ++F     
Sbjct: 963  PATFVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVESTA 1020

Query: 2301 SLDIQHCVPEDAGEYSVKAINALG--HCTSAI 2330
             L +     ED+GEY  +A N  G  HC+S +
Sbjct: 1021 VLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIV 1052



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 2/98 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +T+ + P F + + +  ++ G     +  L+  G   + V W  +   I      R  +E
Sbjct: 1145 VTLREPPSFIKKIESTSSLRGGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTFE 1202

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +  +L L  +  +  G Y CQA N  G    S  L V
Sbjct: 1203 NNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV 1240



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            R+ P F + +++  +++ G TA F   L   G   + V W ++   I +   I  T +  
Sbjct: 1148 REPPSFIKKIESTSSLRGG-TAAFQATL--KGSLPITVTWLKDSDEITEDDNIRMTFENN 1204

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
              S+ +S +  + +G Y+C+A N  G
Sbjct: 1205 VASLYLSGIEVKHDGKYVCQAKNDAG 1230



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 3/98 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P FV+    P       N  ++ +    G   M ++WF + + +  G+    + D  
Sbjct: 1430 KEPPYFVE---KPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDT 1486

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
              +L++  A + D+G Y  +  N +G+A + A + V E
Sbjct: 1487 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE 1524



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 37/167 (22%), Positives = 68/167 (40%), Gaps = 18/167 (10%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            S+E +  + P F   L  +E ++  +    E  +T T  P  +V W  N + +++  ++ 
Sbjct: 1611 SIELKVKEPPTFIRELKPVEVVKYSD-VELECEVTGT--PPFEVTWLKNNREIRSSKKYT 1667

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530
                     L I+   P D+GEY C   N  G    +  + ++   + I      K +E 
Sbjct: 1668 LTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFI------KKIEN 1721

Query: 3531 TIDKIAALEGYSGTVDTLTPEAESGNPP-EFTTTPSDLILSENSSAH 3576
            T   + +   +  TV        +G+PP   T    D IL E+ + +
Sbjct: 1722 TTTVLKSSATFQSTV--------AGSPPISITWLKDDQILDEDDNVY 1760



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F  ++  + K++ G S H E ++       +  +WF +GK++    +YR       V
Sbjct: 1901 PPSFTKKLTKMDKVL-GSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSV 1957

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDS 3367
             L++     E++  Y C  +N  G D+
Sbjct: 1958 SLEVNNLELEDTANYTCKVSNVAGDDA 1984



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F K  +  EV  G  V   + +     P  +V W+   R + +G R    ++  
Sbjct: 2554 VQEPPSFVKEPEPLEVLPGKNVTFTSVIR--GTPPFKVNWFRGARELVKGDRCNIYFEDT 2611

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
               L++       +G Y C  +N  G+A  T+ + V
Sbjct: 2612 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 2647



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/105 (21%), Positives = 44/105 (41%), Gaps = 2/105 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  P  F+ ++  H+VE  + +  E          + + W ++G  + +  +   V    
Sbjct: 2647 VKEPAAFLKRLSDHSVEPGKSIILESTYTGTLP--ISVTWKKDGFNITTSEKCNIVTTEK 2704

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
               L+IL     D+G+Y C   N+ G D   A +S  + P  + +
Sbjct: 2705 TCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTE 2749



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K    F++ LS+   V  GK+I LE      G   + V W  +G ++T   +        
Sbjct: 2648 KEPAAFLKRLSDHS-VEPGKSIILESTYT--GTLPISVTWKKDGFNITTSEKCNIVTTEK 2704

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQA 1284
               L+I+++T  D G+Y+    N  G     A+V  +E    VT+ +  +A
Sbjct: 2705 TCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEA 2755



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 2/96 (2%)

Query: 1590 KEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGT 1649
            K+G+    E ++       +KV W+ N+  L    ++  +       L I     EDSG 
Sbjct: 3042 KQGESIQLECKIS--GSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGD 3099

Query: 1650 YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
            Y C A N +G+A  S    V +      +    GAL
Sbjct: 3100 YICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGAL 3135



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            PVFTQ    +  ++ G      C +   G P  +V W ++ K + +S +   T      +
Sbjct: 3123 PVFTQKPSPVGALK-GSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTN 3179

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I ++   D G Y C+A+N +G
Sbjct: 3180 LHILNLEASDVGEYHCKATNEVG 3202



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 2/101 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F     SV  + G  + F + I   G P  K++W K  + +             
Sbjct: 3495 VQEPPSFEQTPDSVEVLPGMSLTFTSVIR--GTPPFKVKWFKGSRELVPGESCNISLEDF 3552

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
               L++  +   +SG+Y+C   +  G A     L V   AT
Sbjct: 3553 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPAT 3593



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 2/103 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  P  F+ ++   +VE    +  E        P + + W ++  L+    R        
Sbjct: 3588 VKEPATFVKRLADFSVETGSPIVLEATYTGT--PPISVSWIKDEYLISQSERCSITMTEK 3645

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
               L+IL    ED  +Y C   N+ G+D  +A +S  + P  I
Sbjct: 3646 STILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFI 3688



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F + L+++     G    F+CR+   G   L+V W+++  L++D + +  +      +
Sbjct: 3781 PFFARKLKDVHETL-GFPVAFECRIN--GSEPLQVSWYKDGVLLKDDANLQTSFVHNVAT 3837

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I        G Y C ASN LG
Sbjct: 3838 LQILQTDQSHIGQYNCSASNPLG 3860



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G  + FEC +  S +P L++ W+ +   L      +++   +  +L I  T +   G Y 
Sbjct: 3795 GFPVAFECRINGS-EP-LQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYN 3852

Query: 2848 CKATNSKGSATTSGSL 2863
            C A+N  G+A++S  L
Sbjct: 3853 CSASNPLGTASSSAKL 3868



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 4/104 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHN-GRSVTVGSRFKTYYDF 1232
            K+ P FV+ LS+   V  GK + L+  +E  G   + V WF + G  V         Y  
Sbjct: 4154 KAPPRFVKKLSDISTVV-GKEVQLQTTIE--GAEPISVVWFKDKGEIVRESDNIWISYSE 4210

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276
                L       A+ G+YT +  N  G     A + V+E + IV
Sbjct: 4211 NIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV 4254



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F + LS     +EG +  LE R+   G   + V W+ N   +   S  +  +    + 
Sbjct: 4914 PSFTKRLSETVEETEGNSFKLEGRVA--GSQPITVAWYKNNIEIQPTSNCEITFKNNTLV 4971

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSA-HTSAIV 1267
            L +  A   D G YT +  N  GSA  TS+IV
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIV 5003



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 3/122 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +T    P F     ++ T  G      C +   G   +   W  +G  +     +R +  
Sbjct: 210  VTEAYPPTFLSRPKSLTTFVGKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWRISDA 267

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH-PSGLEKIQY 1423
             +   L+L ++  +D GVY+C+A+N+ G  +    L +I K   I E +   S + K  +
Sbjct: 268  ENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVH 327

Query: 1424 LE 1425
            LE
Sbjct: 328  LE 329



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/93 (23%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           S E    + P FI+ L+   ++  G NA  + +++        + W+KD + I +S +  
Sbjct: 487 STEIVIKEPPSFIKTLEP-ADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYR 543

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
                  V L I    + D G Y     N++G+
Sbjct: 544 LFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 576



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 3/99 (3%)

Query: 1705 EVITQAPVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            E+I + P   +   + I+V     A  E  +   G P+L+ +W ++G P+ AS +     
Sbjct: 675  ELIVKEPAKIIERAELIQVTAGDPATLEYTV--AGTPELKPKWYKDGRPLVASKKYRISF 732

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
                  L        DSG YT    NE+G +   +T  V
Sbjct: 733  KNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTV 771



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/67 (26%), Positives = 32/67 (47%)

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
            P ++ +WY +G+ L +  +YR S     A L   +    DSG+YT +  N +G +     
Sbjct: 709  PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 768

Query: 1934 LNVQSKE 1940
              V  ++
Sbjct: 769  FTVLDRD 775



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 3/154 (1%)

Query: 1801 FVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQ 1860
            FV+  ASL++     +          +S   +     + V + P F+T+  G   +  G 
Sbjct: 828  FVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTK-PGSKDVLPGS 886

Query: 1861 SAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920
            +   +   +      + + W+   K L SG     + +   ++L++  V   DSG YTCK
Sbjct: 887  AVCLKSTFQG--STPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCK 944

Query: 1921 AINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
              N  G    S  L V+   + +   +    L+K
Sbjct: 945  VSNVAGGVECSANLFVKEPATFVEKLEPSQLLKK 978



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 2/86 (2%)

Query: 1446 FVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALD 1505
            FV + +  + + +G      CK+       +K+ WF N + +    + R         L 
Sbjct: 966  FVEKLEPSQLLKKGDATQLACKVTGTPP--IKITWFANDREIKESSKHRMSFVESTAVLR 1023

Query: 1506 IIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            + D+  EDSG Y C A N  G+D  S
Sbjct: 1024 LTDVGIEDSGEYMCEAQNEAGSDHCS 1049



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 2/87 (2%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            + P  +T      ++ +GD A  + +     +  +T  WF +GQ++  G +Y+ +     
Sbjct: 1241 KEPATITEEAVSIDVTQGDPATLQVKFSGTKE--ITAKWFKDGQELTLGSKYKISVTDTV 1298

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEA 2193
              L I+ T  +DSG Y  +  N +G +
Sbjct: 1299 SILKIISTEKKDSGEYTFEVQNDVGRS 1325



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 3/107 (2%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            I PP F  +L+    + +G     EC V   H   + I+++ + + + ++ ++  +F   
Sbjct: 1337 IIPPSFTKKLKKMDSI-KGSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDN 1393

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQ 2345
               L+I      D+G Y+  A N  GH   +  +TV      + + Q
Sbjct: 1394 TAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 1440



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F+V      A+    + F+  ++  G P  KI+W K+   + +  +        
Sbjct: 1991 VKEPPSFLVKPGRQQAIPDSTVEFKAILK--GTPPFKIKWFKDDVELVSGPKCFIGLEGS 2048

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
               L++ S++   +G+YTC   +  G      +L VT
Sbjct: 2049 TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVT 2085



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 19/65 (29%), Positives = 32/65 (49%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI+WFK+ V L +G +     +     L++ S+    +G YTC  TN +G    T  
Sbjct: 2022 PPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTM 2081

Query: 2732 IKIED 2736
            + + +
Sbjct: 2082 LLVTE 2086



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            PVF+     +E L+  E    E  L+ T  P  +V WY + + L++  +++         
Sbjct: 2182 PVFSSFPPIVETLKNAE-VSLECELSGT--PPFEVVWYKDKRQLRSSKKYKIASKNFHTS 2238

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            + I      D GEY C+A N  G      ++K++
Sbjct: 2239 IHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLK 2272



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            +++P F     S D ++ G+    E  V     P ++I W K+   +  G     T    
Sbjct: 2933 KKSPFFDIKPVSID-VIAGESADFECHVTG-AQP-MRITWSKDNKEIRPGGNYTITCVGN 2989

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               L I  +   DSG YTC+ATN +G+ + +A + +++
Sbjct: 2990 TPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE 3027



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 4/95 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK-TINDFGFV 3615
            PP F  TP  + +    S  F    +       +V+WF   + L+ G     ++ DF   
Sbjct: 3498 PPSFEQTPDSVEVLPGMSLTFTS--VIRGTPPFKVKWFKGSRELVPGESCNISLEDF-VT 3554

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             LE+  V   ++G Y+C  TN  G A+ +  L VK
Sbjct: 3555 ELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 3589



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 3/98 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P F       D L  G +V   + V  +  P   + WFK    L  G R   + + 
Sbjct: 4436 VREPPSFVQKPDPMDVLT-GTNVTFTSIV--KGTPPFSVSWFKGSSELVPGDRCNVSLED 4492

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             +  L +  +    SG YTC  +N  G+A  T  + I+
Sbjct: 4493 SVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 4530



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 7/97 (7%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            +K+ W  + + +  G +++++       L ++ V + DSG YTC A N+ G+        
Sbjct: 4847 IKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKD------S 4900

Query: 3003 CTSKDNLIERTQHPKGTEGL-EKIQNLEDSLRKEPGQ 3038
            CT++ N+ ER   P  T+ L E ++  E +  K  G+
Sbjct: 4901 CTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGR 4937



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 8/101 (7%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV++ P + R L ++   EG    +  +        ++ EWF NG+ +K   R +   E
Sbjct: 5405 LTVIE-PAWERHLQDVTLKEGQTCTMTVQFSV---PNVKSEWFRNGRILKPQGRHKTEVE 5460

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                 L +  V  ED G YTC    +  +  TS  LR+ A+
Sbjct: 5461 HKVHKLTIADVRAEDQGQYTC----KYEDLETSAELRIEAE 5497



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 5/122 (4%)

Query: 1707 ITQA--PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            +T+A  P F    K +     +AA F   +   G P +   W ++G  +  S        
Sbjct: 210  VTEAYPPTFLSRPKSLTTFVGKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWRISDA 267

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH-ESALQKIQQ 1823
                 L +  +  +D G Y+C+A N+ G  +  + L +  K     E +  +SA+ K   
Sbjct: 268  ENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVH 327

Query: 1824 LE 1825
            LE
Sbjct: 328  LE 329



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/74 (28%), Positives = 30/74 (40%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   +   W KDG  +  S             L + ++T+ D G Y+C+A N  G     
Sbjct: 241  GTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQ 300

Query: 997  ANLTIVTKKDIIAE 1010
            A L I+ K   I E
Sbjct: 301  AELIIIDKPHFIKE 314



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 7/109 (6%)

Query: 2218 EKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIE 2277
            E +  + +   ST I ++EP    P F+  L     +  G  A  +C+V         I 
Sbjct: 476  EAVNDVGSDSCSTEIVIKEP----PSFIKTLE-PADIVRGTNALLQCEVSGTGP--FEIS 528

Query: 2278 FYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHC 2326
            ++ + K ++S+ ++ +      V L+I      D GEY     N +G C
Sbjct: 529  WFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKC 577



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            +++ P F   L+  D +V G +  L+ +V   T P  +I WFK+   + +  + +     
Sbjct: 492  IKEPPSFIKTLEPAD-IVRGTNALLQCEVSG-TGP-FEISWFKDKKQIRSSKKYRLFSQK 548

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGE 2725
             LV L I S  + D G Y C   N +G+
Sbjct: 549  SLVCLEIFSFNSADVGEYECVVANEVGK 576



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 3410 TSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRF 3469
            TSV E   K P   +  + +  +  G+ A  E  +  T  P LK +WY +G+ L A  ++
Sbjct: 671  TSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGT--PELKPKWYKDGRPLVASKKY 728

Query: 3470 RTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEA 3504
            R         L+       DSG+Y     N  G +
Sbjct: 729  RISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSS 763



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 3/114 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F     + +V  G  V L++T       T+R  W+   + +  G     T +  
Sbjct: 867  VQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIR--WFKGNKELVSGGSCYITKEAL 924

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKK 2087
              +L++      D+GTY CK +N  G    ++++ V  +   +++ L+  +L K
Sbjct: 925  ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV-KEPATFVEKLEPSQLLK 977



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F VE   + DV     V     V   G   M I WF + +   +G+      D    
Sbjct: 1432 PPYF-VEKPQSQDVNPNTRVQLKALVG--GTAPMTIKWFKDNKELHSGAARSVWKDDTST 1488

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +L++    A D+G Y C+ +N  G+AT+ A +
Sbjct: 1489 SLELFAAKATDSGTYICQLSNDVGTATSKATL 1520



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 8/119 (6%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            +P  I+  A    + E   + LE  V     P+LK++W  +GK +     F ++ +    
Sbjct: 1804 EPAQIVEKAKSVDVTEKDPMTLECVVA--GTPELKVKWLKDGKQIVPSRYFSMSFENNVA 1861

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNL 3028
            +  +  V ++DSG YT K  N     F SS+  C +   ++++   P  T+ L K+  +
Sbjct: 1862 SFRIQSVMKQDSGQYTFKVEND----FGSSS--CDAYLRVLDQNIPPSFTKKLTKMDKV 1914



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/106 (18%), Positives = 47/106 (44%), Gaps = 3/106 (2%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            +D+  PP F  ++     ++   +   EC+++  G   +  +WF +GK +    ++  + 
Sbjct: 1896 LDQNIPPSFTKKLTKMDKVLG-SSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVC 1952

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                V++    +  ED+  Y C+ +N+ G D    ++     P  +
Sbjct: 1953 HERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFL 1998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 1982 KPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILY 2041
            KP+ + +V  G     E  +T      MR+ W  + + ++ G  +  T       L IL 
Sbjct: 2941 KPV-SIDVIAGESADFECHVTGAQP--MRITWSKDNKEIRPGGNYTITCVGNTPHLRILK 2997

Query: 2042 AYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                D+G Y C+ATN VG+ + ++ + V
Sbjct: 2998 VGKGDSGQYTCQATNDVGKDMCSAQLSV 3025



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 4/108 (3%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN-GKPIKTGHRFRPAYEFDY 1367
            + P+F + L +  T+ G  V L   ++  G Q + V W  + G+ I+     R ++  + 
Sbjct: 3214 EPPRFVKKLSDTSTLIGDAVELRAIVE--GFQPISVVWLKDRGEVIRESENTRISFIDNI 3271

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              L L S    +SG Y CQ  N  G    S  L V+ +   I+E   P
Sbjct: 3272 ATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL-EPARIIEKPEP 3318



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 6/114 (5%)

Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297
            +I PP F+ +L+    +  G +   EC+V       + + ++ +G  + S  +   +F  
Sbjct: 3402 RIVPPSFIRKLKDVNAIL-GASVVLECRVSG--SAPISVGWFQDGNEIVSGPKCQSSFSE 3458

Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
               +L++    P D G Y+  A N  G    +  +TV    S     Q P+ +E
Sbjct: 3459 NVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSF---EQTPDSVE 3509



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 2/112 (1%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P     LK+V    G     E R+     A + V W+ +   + SG +   + +     L
Sbjct: 3406 PSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 3463

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN 1689
            ++    P D+G YTC A N  G    S +  V    S          LP ++
Sbjct: 3464 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMS 3515



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +K+     G  V LE  ++      + V W+ +G  +  G + ++++      L
Sbjct: 3406 PSFIRKLKDVNAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 3463

Query: 2038 DILYAYAEDTGTYMCKATNAVG 2059
            ++      DTG Y C A N  G
Sbjct: 3464 NLSLLEPSDTGIYTCVAANVAG 3485



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/90 (24%), Positives = 37/90 (41%), Gaps = 2/90 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + PI       +E  +G   H E  L         V WY + + L+SG ++   +     
Sbjct: 4062 EPPIFRKKPHPIETLKGADVHLECEL--QGTPPFHVSWYKDKRELRSGKKYKIMSENFLT 4119

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSG 1665
            ++ I++    D G Y C+A N +G     G
Sbjct: 4120 SIHILNVDAADIGEYQCKATNDVGSDTCVG 4149



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 4/111 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P FV +P  ++ V+ G +V F   ++        V WFK    +  G R     +     
Sbjct: 4440 PSFVQKPDPMD-VLTGTNVTFTSIVKGTPP--FSVSWFKGSSELVPGDRCNVSLEDSVAE 4496

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQ 1554
            L++ D+    SG YTC   N  G    +  L  ++    V+   N+  +E+
Sbjct: 4497 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRL-NDYSIEK 4546



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 18/69 (26%), Positives = 31/69 (44%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W +    +   +R     +     L +  V+   SG YTC   NE G+A  +
Sbjct: 4465 GTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCT 4524

Query: 1798 STLFVQSKA 1806
            + L++++ A
Sbjct: 4525 THLYIKAPA 4533



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/106 (24%), Positives = 53/106 (50%), Gaps = 6/106 (5%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S R+ + E K +PP F   L     V  G++A FEC V       +++ +  + + ++S 
Sbjct: 4806 SARLILTEGK-NPPFFDIRLAPVDAVV-GESADFECHVTGTQP--IKVSWAKDSREIRSG 4861

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALG--HCTSAISM 2332
             ++ I++      L +      D+G+Y+  A+N +G   CT+ +++
Sbjct: 4862 GKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNI 4907



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 2/105 (1%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   L+      EG+    E RV   + P +T+ W+ N  +I+       T     + 
Sbjct: 4914 PSFTKRLSETVEETEGNSFKLEGRVAG-SQP-ITVAWYKNNIEIQPTSNCEITFKNNTLV 4971

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQH 2213
            L +      D+G Y CK +N  G A+ T ++ +   +   +  QH
Sbjct: 4972 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQH 5016



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 18/41 (43%), Positives = 25/41 (60%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK 3148
            LEI  T  TDSG Y C A N+ G+ E +V L+  ++ K +K
Sbjct: 5177 LEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEK 5217



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 3/82 (3%)

Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631
            ++T   P     L++V +KEGQ        +  S   +K EW+ N + LK   R      
Sbjct: 5404 KLTVIEPAWERHLQDVTLKEGQTCTMT---VQFSVPNVKSEWFRNGRILKPQGRHKTEVE 5460

Query: 1632 FGFVALDIMSCLPEDSGTYTCR 1653
                 L I     ED G YTC+
Sbjct: 5461 HKVHKLTIADVRAEDQGQYTCK 5482



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 11/159 (6%)

Query: 1207 PTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAH---T 1263
            P ++ EWF NGR +    R KT  +     L I    + D G+YT +  +   SA     
Sbjct: 5436 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIE 5495

Query: 1264 SAIVRVIERSDIVTDTQNEQAIEQIQL-LEDAARRTKQVREDITVMQAPQFSR------- 1315
            +  ++  +R   +  ++++ A  + ++  +DA     +   ++T  Q   F         
Sbjct: 5496 AEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYM 5555

Query: 1316 ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
             +HN+   +     +  RL+P G+     E +   K IK
Sbjct: 5556 TIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIK 5594



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/56 (35%), Positives = 31/56 (55%)

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEV 1530
            N+K EWF+NG+ +    R +   +     L I D+ AED G YTC+  +L  + E+
Sbjct: 5437 NVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAEL 5492



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 4/72 (5%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            FT+ +QNI  + E Q+A F+C    V      V W++    + +S +    +D     MT
Sbjct: 5501 FTKRIQNIV-VSEHQSATFECE---VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMT 5556

Query: 2438 ISHVRDEDEGVY 2449
            I +V  +DEGVY
Sbjct: 5557 IHNVTPDDEGVY 5568



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 3557 PPEFTTTPSDLILSEN----SSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            P +F     D+IL+E+    SSA FEC + P   S+    W  +G  +    + + I D 
Sbjct: 7801 PLKFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADG 7857

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
                L I  V   DAG YTC     + E T + KL V+
Sbjct: 7858 KDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 7895



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 1/85 (1%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
            G+ A F+  +S +     TW K+G  +  S KH  I       L + + Q SD+G YT +
Sbjct: 7820 GSSAIFECLVSPSTAI-TTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCV 7878

Query: 340  AENPNGCIVTSGYLAVESPTESYVQ 364
                N    ++  L VE     +V+
Sbjct: 7879 LRLGNKEKTSTAKLVVEELPVRFVK 7903



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 3/91 (3%)

Query: 2369 EPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428
            E V ++ P F + L+  D I  G  A   C +   G    ++ WF+++K I  S +    
Sbjct: 489  EIVIKEPPSFIKTLEPAD-IVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLF 545

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                 V + I      D G Y C  +N +G+
Sbjct: 546  SQKSLVCLEIFSFNSADVGEYECVVANEVGK 576



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 18/51 (35%), Positives = 24/51 (47%)

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            L + W+  NK L SG     T      +L++      DSGTYTC+  N  G
Sbjct: 900  LTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAG 950



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/106 (22%), Positives = 46/106 (43%), Gaps = 2/106 (1%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++   F   L+    L +G    L  +V     P +KI WF N   +   ++ + +F  
Sbjct: 960  VKEPATFVEKLEPSQLLKKGDATQLACKVTGT--PPIKITWFANDREIKESSKHRMSFVE 1017

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                L +  +  +DSG Y C+A N  G    ++ + +++  +   E
Sbjct: 1018 STAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKE 1063



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 2/96 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP F+   +S       ++  +  +   G   M I+W K+ + + + +  +      
Sbjct: 1429 VKEPPYFVEKPQSQDVNPNTRVQLKALVG--GTAPMTIKWFKDNKELHSGAARSVWKDDT 1486

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
              SL++ +    DSG Y C+  +  G A +KA L V
Sbjct: 1487 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFV 1522



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 17/62 (27%), Positives = 33/62 (53%)

Query: 3452 LKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMK 3511
            + ++W+ + K L +G+    + D     LE+      DSG Y+C+  N+ G A + A++ 
Sbjct: 1462 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 1521

Query: 3512 VQ 3513
            V+
Sbjct: 1522 VK 1523



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 37/183 (20%), Positives = 74/183 (40%), Gaps = 10/183 (5%)

Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314
            DS   I E ++  G+   +      EPP F +    + + ++      E  L     P  
Sbjct: 2155 DSGDFICEAQNPAGSTSCSTKVIVKEPPVF-SSFPPIVETLKNAEVSLECELSGT--PPF 2211

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKC 3374
            +V W+ + ++L    +Y+         + IL     + GEY C A N++G D+    +K 
Sbjct: 2212 EVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL 2271

Query: 3375 ------TSKEN-LILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLS 3427
                   SK N L + +  P  ++  +E  Q +    ++ K+  + E +     F   ++
Sbjct: 2272 KEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVA 2331

Query: 3428 NIE 3430
             ++
Sbjct: 2332 TLQ 2334



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 4/119 (3%)

Query: 3253 QPDSLAK-IRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDD 3311
            +P +  K I ++++  G ++   +    EP   + +   +T  V G++   E ++     
Sbjct: 2339 EPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTV-GETCTLECKVAGT-- 2395

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
            P+L VEW+ +GK L    +++      I  L IL    +++G Y     N +G+ S  A
Sbjct: 2396 PELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTA 2454



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 2/87 (2%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            + ++P  +        V  G+    ECK+    +  L VEW+K+G+ +T   + +     
Sbjct: 2364 MVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPE--LSVEWYKDGKLLTSSQKHKFSFYN 2421

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVG 1526
               +L I+ +  +D+G YT +  N VG
Sbjct: 2422 KISSLRILSVERQDAGTYTFQVQNNVG 2448



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/69 (27%), Positives = 37/69 (53%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P+L VEW ++G  + +S +          +L +  V  +D+GTYT +  N +G++  +
Sbjct: 2394 GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCT 2453

Query: 1798 STLFVQSKA 1806
            + + V  +A
Sbjct: 2454 AVVDVSDRA 2462



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L+N   +  G +   +C++   G   + V WF  +  I   ++   T      +
Sbjct: 2465 PSFTRRLKNTGGVL-GASCILECKV--AGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCT 2521

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + ++ +   D G Y C A+N+ G
Sbjct: 2522 LQLNSLDSSDMGNYTCVAANVAG 2544



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 1/70 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P F   P ++ V  GE A F C VTG    R+ W  +   I  G  Y +T  G   H  I
Sbjct: 2936 PFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRI 2995

Query: 4170 PKTRQYDTGK 4179
             K  + D+G+
Sbjct: 2996 LKVGKGDSGQ 3005



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            ++I W  + K +  G  + +T       L ++ V + DSG YTC+A N  G+   S+ + 
Sbjct: 2965 MRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLS 3024

Query: 3003 CTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEP 3036
                   +++ +  K  +  E IQ LE  +   P
Sbjct: 3025 VKEPPKFVKKLEASKVAKQGESIQ-LECKISGSP 3057



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 2/99 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  P + I   + +T   G     E  +   G P +  +W K+G+ + A S+    F   
Sbjct: 3306 VLEPARIIEKPEPMTVTTGNPFALECVV--TGTPELSAKWFKDGRELSADSKHHITFINK 3363

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
              SL +    + D G Y+    ++ G +     +HV+ R
Sbjct: 3364 VASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDR 3402



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L  + N   G     ECRV       +++ WF +G +I +G + +++       
Sbjct: 3406 PSFIRKLKDV-NAILGASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L++      D+G Y C A N  G    +  L V
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 3495



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 4/105 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKD-GRPVEASSRITTFFNFGYV 967
            P F   + D IS   G     +  +E  G   + V W KD G  V  S  I   ++    
Sbjct: 4157 PRFVKKLSD-ISTVVGKEVQLQTTIE--GAEPISVVWFKDKGEIVRESDNIWISYSENIA 4213

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
             L    V   +AG YTC+  N  G     A L+++    I+ + +
Sbjct: 4214 TLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPE 4258



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/116 (22%), Positives = 50/116 (43%), Gaps = 3/116 (2%)

Query: 1690 QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRN 1749
            Q+++ +  Q   A   V+  A +   P + I+V        E  +   G P+L  +W ++
Sbjct: 4231 QIKNDAGMQECFATLSVLEPATIVEKP-ESIKVTTGDTCTLECTV--AGTPELSTKWFKD 4287

Query: 1750 GVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            G  + + N+           L +  V P DSG Y+    N +G+   +++L V  +
Sbjct: 4288 GKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 4343



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/87 (26%), Positives = 33/87 (37%), Gaps = 2/87 (2%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F+ +     V     V F   V  K  P   + W++    L  G R     +  
Sbjct: 4436 VREPPSFVQKPDPMDVLTGTNVTFTSIV--KGTPPFSVSWFKGSSELVPGDRCNVSLEDS 4493

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGE 3912
               L++  V    SGEY C   N+ G+
Sbjct: 4494 VAELELFDVDTSQSGEYTCIVSNEAGK 4520



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/88 (26%), Positives = 35/88 (39%), Gaps = 3/88 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +  P FVQ   +P  V  G N+     ++  G P   V WF     +  G R     +  
Sbjct: 4437 REPPSFVQK-PDPMDVLTGTNVTFTSIVK--GTPPFSVSWFKGSSELVPGDRCNVSLEDS 4493

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSA 1261
               L++    ++ +GEYT    N  G A
Sbjct: 4494 VAELELFDVDTSQSGEYTCIVSNEAGKA 4521



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 2/105 (1%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            +  P KF+ ++  +++E+ + +  E        P + + W +NG  +    R        
Sbjct: 4529 IKAPAKFVKRLNDYSIEKGKPLILEGTFTGT--PPISVTWKKNGINVTPSQRCNITTTEK 4586

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
               L+I     ED+G+Y C   N  G+D   A I   + P  + Q
Sbjct: 4587 SPILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQ 4631



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F   L  +D +  G++A F+C +   G   +KV W ++ + I    +   ++      
Sbjct: 4818 PFFDIRLAPVDAVV-GESADFECHV--TGTQPIKVSWAKDSREIRSGGKYQISYLENSAH 4874

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            +T+  V   D G Y C A N +G+
Sbjct: 4875 LTVLKVDKGDSGQYTCYAVNEVGK 4898



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 4003 PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAV 4062
            PN+K EWF NG+ L  + R     +     +    V  ED G+Y C+  +L    ET A 
Sbjct: 5436 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDL----ETSAE 5491

Query: 4063 IKTTGKP 4069
            ++   +P
Sbjct: 5492 LRIEAEP 5498



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/72 (26%), Positives = 35/72 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P ++  W K+G  L+     + +       L +++L   D G+Y+CKA+N  G  +  A 
Sbjct: 243  PVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAE 302

Query: 2732 IKIEDRHWLLGE 2743
            + I D+   + E
Sbjct: 303  LIIIDKPHFIKE 314



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 2/72 (2%)

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
            +K+ W+ N++ +K  S+   +       L +     EDSG Y C A N  G    S I I
Sbjct: 994  IKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI 1053

Query: 1669 VHSKKSIYLESQ 1680
            V  K+S Y   +
Sbjct: 1054 V--KESPYFTKE 1063



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/90 (23%), Positives = 41/90 (45%), Gaps = 7/90 (7%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIP--VGDPTLKVEWFRNEKLIEDSSRITKT 2428
            + ++ P FT+  + I+ ++E     +D  L+    G P  ++ WF++  ++    +    
Sbjct: 1053 IVKESPYFTKEFKPIEVLKE-----YDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTF 1107

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                 VS+ I      D G Y CR +N +G
Sbjct: 1108 IQDHLVSLQILKFVAADAGEYQCRVTNEVG 1137



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/98 (22%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            S ++P   T     I + +G  A  + +    G   +  +W KDG+ +   S+       
Sbjct: 1239 SVKEPATITEEAVSIDVTQGDPATLQVKFS--GTKEITAKWFKDGQELTLGSKYKISVTD 1296

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
                L I S    D+G YT    N +G+++  A + ++
Sbjct: 1297 TVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVL 1334



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 5/104 (4%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY-DF 4028
            K+PP FV + QSQ        T+ + +    G   M ++WF + K L H      ++ D 
Sbjct: 1430 KEPPYFVEKPQSQDV---NPNTRVQLKALVGGTAPMTIKWFKDNKEL-HSGAARSVWKDD 1485

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
               ++        DSG Y+C+ +N  G   +KA +     P  +
Sbjct: 1486 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFI 1529



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 15/65 (23%), Positives = 34/65 (52%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G + + ++W KD + + + +  + + +    +L + +    D+G Y C+  N +G AT+ 
Sbjct: 1458 GTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSK 1517

Query: 997  ANLTI 1001
            A L +
Sbjct: 1518 ATLFV 1522



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/70 (25%), Positives = 33/70 (47%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            + I+W+ + K L  G+   +  D    +L+L      DSG Y C+  N  G A + +T++
Sbjct: 1462 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 1521

Query: 3003 CTSKDNLIER 3012
                   I++
Sbjct: 1522 VKEPPQFIKK 1531



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/62 (27%), Positives = 32/62 (51%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            MT++W+ + K++ S      + D    +L++ + +A DSG Y     N  G A   A++ 
Sbjct: 1462 MTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 1521

Query: 1135 VE 1136
            V+
Sbjct: 1522 VK 1523



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/91 (20%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P+++  + A   +  G    LE ++     P++++ W+ N   L    ++++T       
Sbjct: 2088 PKFVKKLEASKIVKAGDSSRLECKIA--GSPEIRVVWFRNEHELPASDKYRMTFIDSVAV 2145

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + + ++   DSG + C+A N  G    S+ V
Sbjct: 2146 IQMNNLSTEDSGDFICEAQNPAGSTSCSTKV 2176



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/87 (22%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++ + PVF+     +   +N     E  L   G P   V W ++   + +S +       
Sbjct: 2177 IVKEPPVFSSFPPIVETLKNAEVSLECELS--GTPPFEVVWYKDKRQLRSSKKYKIASKN 2234

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELG 1792
             + ++++  V+  D G Y C+A NE+G
Sbjct: 2235 FHTSIHILNVDTSDIGEYHCKAQNEVG 2261



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/75 (22%), Positives = 34/75 (45%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +  P  K+ W+   + L +G R  +  +     L+L ++    SG YTC   N  G+A  
Sbjct: 2582 RGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASC 2641

Query: 2998 SSTVYCTSKDNLIER 3012
            ++ ++       ++R
Sbjct: 2642 TTRLFVKEPAAFLKR 2656



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 1/69 (1%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q +    P++ + WY     L     ++        TL    V   DSG YTCKA N  G
Sbjct: 2764 QCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIG 2823

Query: 2994 EAFTSSTVY 3002
             A +S TV+
Sbjct: 2824 TA-SSKTVF 2831



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 33/148 (22%), Positives = 68/148 (45%), Gaps = 5/148 (3%)

Query: 1793 EAVTSSTLFVQSKASLQLESQHESALQK-IQQLEDSSRYQRREDVEVAVNQAPRFITQLN 1851
            E+  +   F+ + A+LQL S   S   K I Q+++ +    RE   V     P  I +  
Sbjct: 3259 ESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGM--RECSAVLTVLEPARIIEKP 3316

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
             P  ++ G     EC +   P+  +  +W+ +G+ L +  ++  +     A+L I     
Sbjct: 3317 EPMTVTTGNPFALECVVTGTPE--LSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM 3374

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
             D G Y+ +  N++G++  ++ ++V  +
Sbjct: 3375 SDKGLYSFEVKNSVGKSNCTVSVHVSDR 3402



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 2/94 (2%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   +E  + + V  G P   +C V   G P +   WF +GR  +  S+ H        +
Sbjct: 3309 PARIIEKPEPMTVTTGNPFALECVV--TGTPELSAKWFKDGRELSADSKHHITFINKVAS 3366

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            L I      D G Y+    N  G +  T  +  S
Sbjct: 3367 LKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVS 3400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F + L++++ I  G +   +CR+   G   + V WF++   I    +   +      +
Sbjct: 3406 PSFIRKLKDVNAIL-GASVVLECRVS--GSAPISVGWFQDGNEIVSGPKCQSSFSENVCT 3462

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + +S +   D G+Y C A+N+ G
Sbjct: 3463 LNLSLLEPSDTGIYTCVAANVAG 3485



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 3/91 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L ++     G    FE R+  ++   L+V WY +G  LK  +  +T        
Sbjct: 3781 PFFARKLKDVHETL-GFPVAFECRINGSEP--LQVSWYKDGVLLKDDANLQTSFVHNVAT 3837

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASM 3510
            L+I  T     G+Y C A N  G A ++A +
Sbjct: 3838 LQILQTDQSHIGQYNCSASNPLGTASSSAKL 3868



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 4/97 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            P      P  + ++   +   EC +    + S +  WF +GK L + ++ K I+ F  V 
Sbjct: 4250 PATIVEKPESIKVTTGDTCTLECTVAGTPELSTK--WFKDGKELTSDNKYK-ISFFNKVS 4306

Query: 3617 -LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             L+I  V   D+G+Y+ +  N  G+ + +  LQV  R
Sbjct: 4307 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 4343



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/72 (23%), Positives = 32/72 (44%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P + + W+  G  +  G +++ T       L +  + E DSG YTC A N  G    S+ 
Sbjct: 4374 PPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAP 4433

Query: 3001 VYCTSKDNLIER 3012
            +      + +++
Sbjct: 4434 LTVREPPSFVQK 4445



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 2/84 (2%)

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            ++V W  + R ++ G +++ +Y      L +L     D+G Y C A N VG+   T+ + 
Sbjct: 4847 IKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLN 4906

Query: 2069 VDAKSGLYLDTLDEQRLKKIQELE 2092
            +  K  L   +  ++  + ++E E
Sbjct: 4907 I--KERLIPPSFTKRLSETVEETE 4928



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 9/122 (7%)

Query: 1825 EDSSRYQ-RREDVEVA----VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879
            ED  +Y  + ED+E +    +   P   T+      +SE QSA +EC +  + D    V 
Sbjct: 5474 EDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVS-FDDAI--VT 5530

Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA-INNLGQAVSSIRLNVQS 1938
            WY     L    +Y   ND     + I  V  +D G Y+  A +   G+A S+  L + +
Sbjct: 5531 WYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTT 5590

Query: 1939 KE 1940
            KE
Sbjct: 5591 KE 5592



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 5/91 (5%)

Query: 626  PPGEEDRVYP----PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIE-WLKNGQSIE 680
            PP E    Y     P +F+  +K +   E   +      E +  P+  I  W+K+G +I 
Sbjct: 7787 PPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIR 7846

Query: 681  ASSRFTSIFRFGYISLDMLSLNIQDSGEYTC 711
             S +   I       L ++ + + D+GEYTC
Sbjct: 7847 ESPKHRFIADGKDRKLHIIDVQLSDAGEYTC 7877



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNA--RAVGTPTPRIT-WQKDGVPIIPNPELRIHTDG 543
            + V  KFV+    + + E E V  +A    + +P+  IT W KDG  I  +P+ R   DG
Sbjct: 7798 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADG 7857

Query: 544  GASTLDIPRAKASDAAWYQC 563
                L I   + SDA  Y C
Sbjct: 7858 KDRKLHIIDVQLSDAGEYTC 7877



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/87 (20%), Positives = 38/87 (43%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            + E P F K ++ A++  G    L+  ++        + W+ + + ++   +++      
Sbjct: 492  IKEPPSFIKTLEPADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLFSQKS 549

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
             V L+I    + D G Y C   N VG+
Sbjct: 550  LVCLEIFSFNSADVGEYECVVANEVGK 576



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/84 (23%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F ++  +  D+  G      C V   G     I WF + +   +  +    +    +
Sbjct: 495  PPSF-IKTLEPADIVRGTNALLQCEVSGTGP--FEISWFKDKKQIRSSKKYRLFSQKSLV 551

Query: 3754 ALDIDYIYARDAGEYTCRATNKWG 3777
             L+I    + D GEY C   N+ G
Sbjct: 552  CLEIFSFNSADVGEYECVVANEVG 575



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 17/59 (28%), Positives = 24/59 (40%)

Query: 934 EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ 992
           E  G     + W KD + + +S +   F     V L I S    D G Y C   N +G+
Sbjct: 518 EVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 576



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/115 (21%), Positives = 48/115 (41%), Gaps = 3/115 (2%)

Query: 3264 ESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGK 3323
            E+  G+Q         EP K I + + + ++  G  A  E  +     P+LK +W+ +G+
Sbjct: 664  ENEAGSQTSVGELIVKEPAKIIERAE-LIQVTAGDPATLEYTVAGT--PELKPKWYKDGR 720

Query: 3324 KLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
             L    +YR      +  L        +SG+Y    +N++G  S +       ++
Sbjct: 721  PLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRD 775



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 3/99 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   +E  + I V  G P   +  V   G P ++  W+ +GRP     +           
Sbjct: 681  PAKIIERAELIQVTAGDPATLEYTV--AGTPELKPKWYKDGRPLVASKKYRISFKNNVAQ 738

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            L        D+G+YT   +N+ GS++     T    RDI
Sbjct: 739  LKFYSAELHDSGQYTFEISNEVGSSSCETTFTV-LDRDI 776



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 2924 VEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGI 2983
            ++G  + LE  V   +   + I+W+ + + +    ++K +       L++  +   DSG 
Sbjct: 1352 IKGSFIDLECIVAGSHP--ISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGT 1409

Query: 2984 YTCKAYNKRGEAFTSSTVYCTSKDNLIERTQ 3014
            YTC A NK G    S  +        +E+ Q
Sbjct: 1410 YTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 1440



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/113 (22%), Positives = 44/113 (38%), Gaps = 3/113 (2%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            I+  V   P F+   K +E V++   V  EC++        +V W KN + +    ++  
Sbjct: 1612 IELKVKEPPTFIRELKPVE-VVKYSDVELECEVTGTPP--FEVTWLKNNREIRSSKKYTL 1668

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
                    L I      D+G Y C   N  G+   S R+  +     ++  +N
Sbjct: 1669 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIEN 1721



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/53 (35%), Positives = 26/53 (49%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724
            P + I W K+   L     +  +F   + TL I S+ N  SG YTC+A N  G
Sbjct: 1740 PPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESG 1792



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 17/63 (26%), Positives = 29/63 (46%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P LKV+W  +GK +     F    +       I     +DSG+Y  +  N++G +   A 
Sbjct: 1833 PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 1892

Query: 3510 MKV 3512
            ++V
Sbjct: 1893 LRV 1895



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/71 (25%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 2924 VEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGI 2983
            V G  +H+E +V       +  +W+ +GK +   ++++L      V+L++ ++   D+  
Sbjct: 1914 VLGSSIHMECKVS--GSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN 1971

Query: 2984 YTCKAYNKRGE 2994
            YTCK  N  G+
Sbjct: 1972 YTCKVSNVAGD 1982



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 3578 ECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATN 3636
            EC++    + S  VEW+ +GK LLT S+    + +  +  L I  V ++DAG YT +  N
Sbjct: 2389 ECKVAGTPELS--VEWYKDGK-LLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQN 2445

Query: 3637 RHGEATVSCKLQVKGR 3652
              G+++ +  + V  R
Sbjct: 2446 NVGKSSCTAVVDVSDR 2461



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 2/93 (2%)

Query: 1967 AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF 2026
            AV D S     P F + +KN     G    LE  +       + V W+     +  G ++
Sbjct: 2454 AVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVA--GSSPISVAWFHEKTKIVSGAKY 2511

Query: 2027 KTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            +TT+      L +    + D G Y C A N  G
Sbjct: 2512 QTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAG 2544



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F R L+D+ E   G       +L   S P ++V WY+DG  +     + + F     +
Sbjct: 2840 PSFARQLKDI-EQTVGLPVTLTCRLNG-SAP-IQVCWYRDGVLLRDHENLQTSFVDNVAT 2896

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            L I+      +G Y+  A N LG A S+A  R+ AR
Sbjct: 2897 LKILQTDLSHSGQYSCSASNPLGTASSSA--RLTAR 2930



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            ++ P F     +ID I  G++A F+C +   G   +++ W ++ K I      T T    
Sbjct: 2933 KKSPFFDIKPVSIDVIA-GESADFECHV--TGAQPMRITWSKDNKEIRPGGNYTITCVGN 2989

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459
               + I  V   D G Y C+A+N +G+
Sbjct: 2990 TPHLRILKVGKGDSGQYTCQATNDVGK 3016



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/68 (26%), Positives = 32/68 (47%)

Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
            R  P  K++WFK    L  G     + +  +  L +  ++  +SG Y+C  TN  G A  
Sbjct: 3523 RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASC 3582

Query: 2729 TASIKIED 2736
            T  + +++
Sbjct: 3583 TTHLFVKE 3590



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 6/92 (6%)

Query: 2911 PEWIIPIAAEH-QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            P +I P+  EH + V G+   L+ +V+    P+++I WY     L     +K+       
Sbjct: 3685 PYFIEPL--EHVEAVIGEPATLQCKVD--GTPEIRISWYKEHTKLRSAPAYKMQFKNNVA 3740

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            +L +  V   D G Y+CKA N  G A  SS V
Sbjct: 3741 SLVINKVDHSDVGEYSCKADNSVG-AVASSAV 3771



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            E P F         L  G+S  F+  +       +K+ W  + +++  G  Y+       
Sbjct: 3874 EVPPFFDLKPVSVDLALGESGTFKCHVTGT--APIKITWAKDNREIRPGGNYKMTLVENT 3931

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L +L   + ++G+Y C A+N  G+DS  A L
Sbjct: 3932 ATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQL 3964



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            KAP   V   N  ++ +G+    E   T T  P + V W  NG ++    R         
Sbjct: 4530 KAPAKFVKRLNDYSIEKGKPLILEGTFTGT--PPISVTWKKNGINVTPSQRCNITTTEKS 4587

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
             ILEI  +  ED+G+Y C   N  G+   +A + +
Sbjct: 4588 PILEIPSSTVEDAGQYNCYIENASGKDSCSAQILI 4622



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 3/91 (3%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            F   L  Y  + +G+ + LE        P + + W KNG+ +T   R   T       L 
Sbjct: 4535 FVKRLNDYS-IEKGKPLILEGTFTGT--PPISVTWKKNGINVTPSQRCNITTTEKSPILE 4591

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            I S   +D+G Y C   N  G+   +A I I
Sbjct: 4592 IPSSTVEDAGQYNCYIENASGKDSCSAQILI 4622



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 2/103 (1%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++ + P F   + D+     Q    +A +   G   + V W++    I    ++      
Sbjct: 584  LLKEPPTFVKKVDDLIALGGQTVTLQAAVR--GSEPISVTWMKGQEVIREDGKIKMSFSN 641

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
            G   L +  V     G YTC A NE G   +   L V+  A +
Sbjct: 642  GVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKI 684



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/51 (33%), Positives = 26/51 (50%)

Query: 2141 LTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            LTI WF   +++ +G     T +    +L++      DSGTY CK +N  G
Sbjct: 900  LTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAG 950



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F V+      +P+   V F   ++  G P  +I WF +     +G +     +    
Sbjct: 1994 PPSFLVKPGRQQAIPDS-TVEFKAILK--GTPPFKIKWFKDDVELVSGPKCFIGLEGSTS 2050

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             L++  + A   G+YTC  TN  GS + T  +
Sbjct: 2051 FLNLYSVDASKTGQYTCHVTNDVGSDSCTTML 2082



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 19/68 (27%), Positives = 28/68 (41%)

Query: 927  AHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
            A      E  G     V W KD R + +S +        + ++ I +V   D G Y C+A
Sbjct: 2197 AEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKA 2256

Query: 987  YNAIGQAT 994
             N +G  T
Sbjct: 2257 QNEVGSDT 2264



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 28/59 (47%)

Query: 2141 LTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
            + + W+ +G  +R     +T+       L IL T    SG Y C A+N LG A ++  L
Sbjct: 2869 IQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 2927



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 19/72 (26%), Positives = 35/72 (48%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            +KI W  + + +  G  +K+T      TL ++ V + D+G YTC A N  G+   S+ + 
Sbjct: 3906 IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLG 3965

Query: 3003 CTSKDNLIERTQ 3014
                   I++ +
Sbjct: 3966 VQEPPRFIKKLE 3977



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/71 (28%), Positives = 33/71 (46%)

Query: 3445 TPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEA 3504
            T    P L  +W+ +GK L + ++++         L+I    P DSG Y     N  G+ 
Sbjct: 4273 TVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKD 4332

Query: 3505 VTTASMKVQGK 3515
              TAS++V  +
Sbjct: 4333 SCTASLQVSDR 4343



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            P KF+ ++ D + + +G+    E        P + V W  NG  +    R          
Sbjct: 4532 PAKFVKRLNDYS-IEKGKPLILEGTFTGT--PPISVTWKKNGINVTPSQRCNITTTEKSP 4588

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            IL+I     E++G+Y C   N  G+DS  A +
Sbjct: 4589 ILEIPSSTVEDAGQYNCYIENASGKDSCSAQI 4620



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 35/137 (25%), Positives = 52/137 (37%), Gaps = 10/137 (7%)

Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
            +E  SG  D+ + +     PP F      + +S   SA  +C+L       + V W+   
Sbjct: 4607 IENASGK-DSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQL--AGTPEIGVSWYKGD 4663

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
              L   +  K         L    V   D+G Y CKA N  GE + S  L V+       
Sbjct: 4664 TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQ------- 4716

Query: 3658 EPQLPSHFKSGTESIQK 3674
            E +LP  F      +Q+
Sbjct: 4717 EQKLPPSFSRQLRDVQE 4733



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 16/47 (34%), Positives = 25/47 (53%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCK 2185
            P++  +WF NG+ ++   R++T  +     L I    AED G Y CK
Sbjct: 5436 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 5482



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/115 (22%), Positives = 47/115 (40%), Gaps = 3/115 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F    K ++    G    F C V   G P +   W  +G   +        +     
Sbjct: 215  PPTFLSRPK-SLTTFVGKAAKFICTV--TGTPVIETIWQKDGAALSPSPNWRISDAENKH 271

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
             L++  +  +D G Y+C+A+NK+G+    A++    K   + E +  Q    +K+
Sbjct: 272  ILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKV 326



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            +KP F + L  P +    +  H E +V    D  +   W  +G +L  G  ++   +   
Sbjct: 307  DKPHFIKELE-PVQSAINKKVHLECQVDE--DRKVTVTWSKDGQKLPPGKDYKICFEDKI 363

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             TL+I      D+G Y+C A N AG
Sbjct: 364  ATLEIPLAKLKDSGTYVCTASNEAG 388



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 2/80 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L       G N   +C V  S     +I WF + K + S  +Y+     S V L+I
Sbjct: 498  FIKTLEPADIVRGTNALLQCEV--SGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEI 555

Query: 2836 THTYEEDSGIYTCKATNSKG 2855
                  D G Y C   N  G
Sbjct: 556  FSFNSADVGEYECVVANEVG 575



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 2/105 (1%)

Query: 2230 TRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA 2289
            ++  V E  +  P  + E      V  G  A  E  V     P L+ ++Y +G+ L ++ 
Sbjct: 669  SQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGT--PELKPKWYKDGRPLVASK 726

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
            ++ I+F      L        D+G+Y+ +  N +G  +   + TV
Sbjct: 727  KYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTV 771



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 1/78 (1%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   +++ W  + R ++ SS+    F      L +  V + D+G Y C A N  G    S
Sbjct: 990  GTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS 1049

Query: 997  ANLTIVTKKDIIAESQHP 1014
             ++ IV +     +   P
Sbjct: 1050 -SIVIVKESPYFTKEFKP 1066



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/97 (21%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            V  ++PP F+ +I+S +SL    T  F+  L   G   + V W  +   +   +     +
Sbjct: 1145 VTLREPPSFIKKIESTSSL-RGGTAAFQATLK--GSLPITVTWLKDSDEITEDDNIRMTF 1201

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
            +    ++    +  +  G+Y+C+A N  G+    A++
Sbjct: 1202 ENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL 1238



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/82 (23%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
            +VT+G P  L+   +   + T +  W+ +G+ +  G ++K +       L I+    +D+
Sbjct: 1254 DVTQGDPATLQVKFSGTKEITAK--WFKDGQELTLGSKYKISVTDTVSILKIISTEKKDS 1311

Query: 2048 GTYMCKATNAVGEAVTTSSVKV 2069
            G Y  +  N VG +   + + V
Sbjct: 1312 GEYTFEVQNDVGRSSCKARINV 1333



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 7/95 (7%)

Query: 3280 EPPKFIT--QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            EPP F+   Q QDV      Q         P     + ++WF + K+L  G     + D 
Sbjct: 1431 EPPYFVEKPQSQDVNPNTRVQLKALVGGTAP-----MTIKWFKDNKELHSGAARSVWKDD 1485

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
                L++      +SG Y C  +N +G  ++KA L
Sbjct: 1486 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATL 1520



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI +I++ T        F+  V     P + I W ++ ++L         +     +
Sbjct: 1712 PPSFIKKIENTTTVLKSSATFQSTVAGS--PPISITWLKDDQILDEDDNVYISFVDSVAT 1769

Query: 3889 LDILYVYAEDSGEYICRAVNDFG 3911
            L I  V    SG Y C+A N+ G
Sbjct: 1770 LQIRSVDNGHSGRYTCQAKNESG 1792



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP F+ +     + +   +  F+A L     P  K++WF +  +L  G +     +   
Sbjct: 1993 EPPSFLVK-PGRQQAIPDSTVEFKAILKGT--PPFKIKWFKDDVELVSGPKCFIGLEGST 2049

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGG 3393
              L++       +G+Y C  TN +G DS    L  T     +   +  + ++ G
Sbjct: 2050 SFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAG 2103



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 4/112 (3%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP-IKTGHRFRPAY 1363
            + + + P+F   L+++  V G    L+  ++  G Q + V+W    +  I+     R  +
Sbjct: 2269 VKLKEPPRFVSKLNSLTVVAGEPAELQASIE--GAQPIFVQWLKEKEEVIRESENIRITF 2326

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              +   L      P ++G Y CQ  N  G       L V+ +  +I+E   P
Sbjct: 2327 VENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVL-EPAVIVEKAGP 2377



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P  + +     ++   ET   EC++A  G P + VEW+ +GK L    +    +     +
Sbjct: 2368 PAVIVEKAGPMTVTVGETCTLECKVA--GTPELSVEWYKDGKLLTSSQKHKFSFYNKISS 2425

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
            +    V  +D+G Y  +  N  G     AV+  + +
Sbjct: 2426 LRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDR 2461



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G N+ F   +  +  P  K+ WF   + L  G R     + +   L++ +     SG YT
Sbjct: 2572 GKNVTFTSVIRGT--PPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 2629

Query: 2848 CKATNSKGSATTSGSL 2863
            C  +N+ G A+ +  L
Sbjct: 2630 CVVSNNAGQASCTTRL 2645



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/87 (20%), Positives = 36/87 (41%), Gaps = 3/87 (3%)

Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431
            T + P F   L+ ++    G +    C++   G P + V W++ +  +  +         
Sbjct: 2740 TLEPPYFVTELEPLE-AAVGDSVSLQCQV--AGTPEITVSWYKGDTKLRPTPEYRTYFTN 2796

Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLG 2458
               ++  + V   D G Y C+A N +G
Sbjct: 2797 NVATLVFNKVNINDSGEYTCKAENSIG 2823



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 2240 SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY 2299
            +PP F T+        +G     +C++     P   + +  + K ++++ +F IT     
Sbjct: 3121 APPVF-TQKPSPVGALKGSDVILQCEISGT--PPFEVVWVKDRKQVRNSKKFKITSKHFD 3177

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISM 2332
             +L I +    D GEY  KA N +G  T + S+
Sbjct: 3178 TNLHILNLEASDVGEYHCKATNEVGSDTCSCSV 3210



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/96 (25%), Positives = 39/96 (40%), Gaps = 2/96 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P F +   + EV  G  + L  T      P  +V+W+   R +  G     + +  
Sbjct: 3495 VQEPPSFEQTPDSVEVLPG--MSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 3552

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
               L++      ++G Y C  TN  G A  T+ + V
Sbjct: 3553 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV 3588



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/75 (21%), Positives = 34/75 (45%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +  P  K++W+   + L  G    ++ +     L+L +V   +SG Y+C   N  G A  
Sbjct: 3523 RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASC 3582

Query: 2998 SSTVYCTSKDNLIER 3012
            ++ ++       ++R
Sbjct: 3583 TTHLFVKEPATFVKR 3597



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 2504 EFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF 2563
            E E P F  +     +L  G+   ++  V   G   ++  W  +  E++ G  ++ T   
Sbjct: 3872 EHEVPPFFDLKPVSVDLALGESGTFKCHVT--GTAPIKITWAKDNREIRPGGNYKMTLVE 3929

Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590
               TL +  V   DAG Y C A N AG
Sbjct: 3930 NTATLTVLKVGKGDAGQYTCYASNIAG 3956



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F +   SV    G    F+  +   G   +KI W K+ + I     +         +
Sbjct: 3876 PPFFDLKPVSVDLALGESGTFKCHV--TGTAPIKITWAKDNREIRPGGNYKMTLVENTAT 3933

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +L +   D+G+YTC A +  G     A L V
Sbjct: 3934 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGV 3966



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDS 2179
            +L  G+   F+C V       + I W  + ++IR G  Y+ T       L +L     D+
Sbjct: 3887 DLALGESGTFKCHVT--GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDA 3944

Query: 2180 GTYMCKATNKLGE 2192
            G Y C A+N  G+
Sbjct: 3945 GQYTCYASNIAGK 3957



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 2/76 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G N+ F   V+ +  P   + WF  +  L  G R   + + S   L++       SG YT
Sbjct: 4454 GTNVTFTSIVKGT--PPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYT 4511

Query: 2848 CKATNSKGSATTSGSL 2863
            C  +N  G A+ +  L
Sbjct: 4512 CIVSNEAGKASCTTHL 4527



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/66 (30%), Positives = 28/66 (42%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q +    P++ + WY     L   + +K+       TL    V   DSG Y CKA N  G
Sbjct: 4646 QCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVG 4705

Query: 2994 EAFTSS 2999
            E   S+
Sbjct: 4706 EVSAST 4711



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            + P F  + + ++  + G  V F+C +       + V W+K+G+P+      +       
Sbjct: 4720 LPPSFSRQLRDVQETV-GLPVVFDCAISG--SEPISVSWYKDGKPLKDSPNVQTSFLDNT 4776

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
              L+I       +G Y+C A N +G+   S RL
Sbjct: 4777 ATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 42/158 (26%), Positives = 68/158 (43%), Gaps = 11/158 (6%)

Query: 3510 MKVQGKRNIILESQLPKGMEGTIDKIAALEG-YSGTVDTLTPEAE---SGNPPEFTTTPS 3565
            +K QG+    +E ++ K      D  A  +G Y+   + L   AE      P +FT    
Sbjct: 5449 LKPQGRHKTEVEHKVHKLT--IADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQ 5506

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            ++++SE+ SA FEC    V+     V W+     L    +    ND     + I  V   
Sbjct: 5507 NIVVSEHQSATFECE---VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPD 5563

Query: 3626 DAGLYTCKA-TNRHGEATVSCKLQVKGRQGIILEPQLP 3662
            D G+Y+  A     GEA  + +L +  ++ I LE + P
Sbjct: 5564 DEGVYSVIARLEPRGEARSTAELYLTTKE-IKLELKPP 5600



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/119 (25%), Positives = 47/119 (39%), Gaps = 4/119 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P FL+   SL     G  A F C V     P +   W  +G  +     +R +       
Sbjct: 216  PTFLSRPKSLTTFV-GKAAKFICTVT--GTPVIETIWQKDGAALSPSPNWRISDAENKHI 272

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQH-PNGLEKIRQLEAQ 2226
            L++     +D G Y CKA+NK G  +    L +    + I + +   + + K   LE Q
Sbjct: 273  LELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQ 331



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 6/114 (5%)

Query: 3959 LTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            + + +L  +DK   P F+ +++   S +  +    ECQ+    D  + V W  +G+ L  
Sbjct: 298  ICQAELIIIDK---PHFIKELEPVQSAINKKV-HLECQVDE--DRKVTVTWSKDGQKLPP 351

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
               +   ++     +       +DSG Y+C A+N  G     A +     P  V
Sbjct: 352  GKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFV 405



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 9/98 (9%)

Query: 1433 TDIIDESVTIK--PRFVTRPKSIE--NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488
            +D     + IK  P F+   K++E  +++ G +   +C++        ++ WFK+ + + 
Sbjct: 483  SDSCSTEIVIKEPPSFI---KTLEPADIVRGTNALLQCEVSGT--GPFEISWFKDKKQIR 537

Query: 1489 IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
               ++R       V L+I    + D G Y C   N VG
Sbjct: 538  SSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVG 575



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/113 (23%), Positives = 44/113 (38%), Gaps = 3/113 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  ++ D I +  G  V     V   G   + + W           ++      G  
Sbjct: 588  PPTFVKKVDDLIALG-GQTVTLQAAVR--GSEPISVTWMKGQEVIREDGKIKMSFSNGVA 644

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
             L I  +     G+YTC A N+ GS T+  ++       I+  ++L Q  +G+
Sbjct: 645  VLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGD 697



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 14/53 (26%), Positives = 29/53 (54%), Gaps = 1/53 (1%)

Query: 4110 PPVFVS-LPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            P  FV  L  +  +++G+  +  C+VTG P  ++ W  N   I   S++++++
Sbjct: 963  PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSF 1015



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 2/82 (2%)

Query: 781  ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
            ++ +G  A  + + +   + T +  W+KDG+ +T  S+           L I+    +D+
Sbjct: 1254 DVTQGDPATLQVKFSGTKEITAK--WFKDGQELTLGSKYKISVTDTVSILKIISTEKKDS 1311

Query: 841  GSYTVRAVNKLGEAISTASIRV 862
            G YT    N +G +   A I V
Sbjct: 1312 GEYTFEVQNDVGRSSCKARINV 1333



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 13/58 (22%), Positives = 28/58 (48%)

Query: 2533 VPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +  G   +  +W+ +  E+    +++ +       L+I+ +   D+G Y C A N+AG
Sbjct: 1362 IVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 1419



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 2/76 (2%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            L  GQ    E Q+     P +++ WY +G  +    +  ++   G  T  +      +SG
Sbjct: 1538 LRNGQSTTFECQIT--GTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSG 1595

Query: 2983 IYTCKAYNKRGEAFTS 2998
             Y C+A N  G A  S
Sbjct: 1596 TYVCEARNDAGTASCS 1611



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/76 (25%), Positives = 28/76 (36%)

Query: 926  FAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCR 985
            ++  E   E  G     V WLK+ R + +S + T         L I      D G Y C 
Sbjct: 1634 YSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCI 1693

Query: 986  AYNAIGQATTSANLTI 1001
              N  G  + S  + +
Sbjct: 1694 VSNEGGSCSCSTRVAL 1709



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F+ +I++ T++++   T F+  +A  G P + + W  + + L   +     +   
Sbjct: 1710 KEPPSFIKKIENTTTVLKSSAT-FQSTVA--GSPPISITWLKDDQILDEDDNVYISFVDS 1766

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
               +    V    SG Y C+A N  G++   A +
Sbjct: 1767 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFL 1800



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/101 (22%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E + I  G P  +++W ++ V + +  +     +     LN+  V+   +G YTC   N+
Sbjct: 2013 EFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTND 2072

Query: 1791 LGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQ 1831
            +G    ++ L V        + +      KI +  DSSR +
Sbjct: 2073 VGSDSCTTMLLVTEPPKFVKKLE----ASKIVKAGDSSRLE 2109



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 3/99 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F++     + L   + V LE ++     P  ++ W+K+   L +  + K     
Sbjct: 2178 VKEPPVFSSFPPIVETLKNAE-VSLECELSGT--PPFEVVWYKDKRQLRSSKKYKIASKN 2234

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               ++ I ++   D G Y CKA N +G      ++K+++
Sbjct: 2235 FHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE 2273



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            PVFT   S +  L+ G +   +  ++ T  P  +V W  + K ++   +F+         
Sbjct: 3123 PVFTQKPSPVGALK-GSDVILQCEISGT--PPFEVVWVKDRKQVRNSKKFKITSKHFDTN 3179

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMK 3511
            L I      D GEY C+A N  G    + S+K
Sbjct: 3180 LHILNLEASDVGEYHCKATNEVGSDTCSCSVK 3211



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/62 (27%), Positives = 31/62 (50%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P  +V W  + K++ +  +++         L IL     + GEY C ATN++G D+   +
Sbjct: 3150 PPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCS 3209

Query: 3372 LK 3373
            +K
Sbjct: 3210 VK 3211



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/65 (26%), Positives = 31/65 (47%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L  +W KDGR + A S+    F     +L I    + D G Y+    N++G++  +
Sbjct: 3335 GTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT 3394

Query: 997  ANLTI 1001
             ++ +
Sbjct: 3395 VSVHV 3399



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/71 (23%), Positives = 33/71 (46%)

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
            P  +V+W+   + L  G     S +     L++  V   +SG+Y+C   N+ G A  +  
Sbjct: 3526 PPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTH 3585

Query: 1934 LNVQSKESIIR 1944
            L V+   + ++
Sbjct: 3586 LFVKEPATFVK 3596



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/61 (27%), Positives = 29/61 (47%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  K++WF  ++ L  G     + +     L++      +SG Y+C  TN  GSA+ +  
Sbjct: 3526 PPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTH 3585

Query: 2863 L 2863
            L
Sbjct: 3586 L 3586



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 3/98 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K+   FV+ L N   + +GK + LE      G P + V W  NG +VT   R        
Sbjct: 4530 KAPAKFVKRL-NDYSIEKGKPLILEGTFT--GTPPISVTWKKNGINVTPSQRCNITTTEK 4586

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               L+I  +T  D G+Y     N  G    SA + ++E
Sbjct: 4587 SPILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE 4624



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/66 (28%), Positives = 29/66 (43%)

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
            + V WY + KPLK       +       L+I       +G Y+C A N +G A +S   I
Sbjct: 4751 ISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLI 4810

Query: 1669 VHSKKS 1674
            +   K+
Sbjct: 4811 LTEGKN 4816



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 2940 DPDLKIEWYFNGK--VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            DP   ++W   GK   L QG R  +        L++ D  + DSG+Y C A+N+ GE
Sbjct: 5145 DPIPNVKWT-KGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGE 5200



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 13/47 (27%), Positives = 24/47 (51%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            P +K EW +NG+ ++   R  +        L +  +  +D G+YTC+
Sbjct: 5436 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 5482



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 41/189 (21%), Positives = 79/189 (41%), Gaps = 15/189 (7%)

Query: 4226 RTETELEKTFEERQVLQRQGV---IDHRPEL-KPKVIKEPETEWQQSVKRKKNEEYYNKL 4281
            R E   +   EE++ +  + +   +  R E+ + +V  E E  + +  +      Y  + 
Sbjct: 6119 RAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEE 6178

Query: 4282 QELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKV 4341
            +E E E  + E  + E   +Y +  +K+        +++R E    +  EVTE R +KK+
Sbjct: 6179 REEEEEAEVTEYEVMEEPEEYVVE-EKL------HIISKRVEA---EPAEVTE-RQEKKI 6227

Query: 4342 TQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVV 4401
              KP+IP   E     K     K+   +K+V        K+   +  E   K   +++V 
Sbjct: 6228 VLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVP 6287

Query: 4402 EGPVKPSKP 4410
               +K  +P
Sbjct: 6288 PKVIKMEEP 6296



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 1445 RFVTRPKSI---ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            +FV   K I   E+   G    FEC + P   S     W K+G  +    + R I D   
Sbjct: 7803 KFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKD 7859

Query: 1502 VALDIIDLIAEDSGIYTC 1519
              L IID+   D+G YTC
Sbjct: 7860 RKLHIIDVQLSDAGEYTC 7877



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/107 (23%), Positives = 47/107 (43%), Gaps = 3/107 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPP F+ ++ D+  L  GQ+   +A  V   +P + V W    + +    + +     G+
Sbjct: 587  EPPTFVKKVDDLIAL-GGQTVTLQAA-VRGSEP-ISVTWMKGQEVIREDGKIKMSFSNGV 643

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQL 3386
             +L I        G+Y C+A N+ G  ++   L       +I  ++L
Sbjct: 644  AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAEL 690



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 16/56 (28%), Positives = 29/56 (51%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSAT 2858
            P LK +W+ + +PL +  +Y+ +   +   L        DSG YT + +N  GS++
Sbjct: 709  PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSS 764



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 2/106 (1%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F   ++         A F+A L   G   + V WL++   I   + +    +  
Sbjct: 1147 LREPPSFIKKIESTSSLRGGTAAFQATL--KGSLPITVTWLKDSDEITEDDNIRMTFENN 1204

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
              +L +  +  +  G Y C+A N+ G    S+ L V+  A++  E+
Sbjct: 1205 VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEA 1250



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 3/121 (2%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P FT  L  +++++ G     E  +     P + ++W+ + + + A  +++         
Sbjct: 1340 PSFTKKLKKMDSIK-GSFIDLEC-IVAGSHP-ISIQWFKDDQEISASEKYKFSFHDNTAF 1396

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            LEIS     DSG Y C A N  G    +  + V+     + + Q       T  ++ AL 
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALV 1456

Query: 3540 G 3540
            G
Sbjct: 1457 G 1457



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/103 (22%), Positives = 44/103 (42%), Gaps = 3/103 (2%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            ++  V++ P F   LK  + +V+   V LE +V     P  ++ W KN   + +  +   
Sbjct: 1612 IELKVKEPPTFIRELKPVE-VVKYSDVELECEVTGT--PPFEVTWLKNNREIRSSKKYTL 1668

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            T    +  L I      D+G Y C  +N  G    +  + +++
Sbjct: 1669 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE 1711



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P+LKV+W  +GK++     +    +  +    I    +++SG+Y     N  G  S  A 
Sbjct: 1833 PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 1892

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L+       +LD  +P      L K+  +  S +
Sbjct: 1893 LR-------VLDQNIPPSFTKKLTKMDKVLGSSI 1919



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGMYHFD 4168
            P V V     +TV  GE     C+V G P+  V W  +G  + +  ++K + Y+ +    
Sbjct: 2368 PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLR 2427

Query: 4169 IPKTRQYDTG 4178
            I    + D G
Sbjct: 2428 ILSVERQDAG 2437



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P+FTQ    P    +G     +  +   G P     W  +  +++   +F+ T       
Sbjct: 3123 PVFTQK-PSPVGALKGSDVILQCEIS--GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTN 3179

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
            L I ++ A+D G Y CKA N  G
Sbjct: 3180 LHILNLEASDVGEYHCKATNEVG 3202



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/63 (28%), Positives = 27/63 (42%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G     V W+KD + V  S +           L I ++   D G Y C+A N +G  T S
Sbjct: 3148 GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVGSDTCS 3207

Query: 997  ANL 999
             ++
Sbjct: 3208 CSV 3210



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 4/107 (3%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKD-GRPVEASSRITTFFNFG 965
            + P F   + D  ++  G      A +E  G   + V WLKD G  +  S      F   
Sbjct: 3214 EPPRFVKKLSDTSTLI-GDAVELRAIVE--GFQPISVVWLKDRGEVIRESENTRISFIDN 3270

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
               L + S    ++G Y C+  N  G    SA LT++    II + +
Sbjct: 3271 IATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPE 3317



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/55 (27%), Positives = 29/55 (52%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G   +   W+ +G E+  G + +++      TL+++ +  +D G+Y C A N AG
Sbjct: 3431 GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAG 3485



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+PP F  +     +L   +    EC+L   G P   V W+ + + L    ++  + +  
Sbjct: 4061 KEPPIFRKKPHPIETLKGADV-HLECELQ--GTPPFHVSWYKDKRELRSGKKYKIMSENF 4117

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
              +++   V   D GEY C+ATN  G D     I     P  V
Sbjct: 4118 LTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFV 4160



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/65 (26%), Positives = 32/65 (49%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L  +W KDG+ + + ++    F      L I +V   D+G Y+    N +G+ + +
Sbjct: 4276 GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCT 4335

Query: 997  ANLTI 1001
            A+L +
Sbjct: 4336 ASLQV 4340



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 4/107 (3%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            +V+E+K   P F+  L +++    G    F+  ++ ++   + V WY +GK LK     +
Sbjct: 4714 TVQEQK-LPPSFSRQLRDVQET-VGLPVVFDCAISGSEP--ISVSWYKDGKPLKDSPNVQ 4769

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
            T        L I  T    +G+Y C A N  G A ++A + +   +N
Sbjct: 4770 TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN 4816



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K PP F  ++    ++V  E+  FEC +   G   +KV W  + + +    ++   Y   
Sbjct: 4815 KNPPFFDIRLAPVDAVVG-ESADFECHVT--GTQPIKVSWAKDSREIRSGGKYQISYLEN 4871

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
               +    V   DSG+Y C A N  G D   A
Sbjct: 4872 SAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTA 4903



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/47 (38%), Positives = 24/47 (51%)

Query: 2538 PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCK 2584
            P+++ EW+ NG  LK   R +T  +     L I  V A D G Y CK
Sbjct: 5436 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 5482



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/52 (36%), Positives = 26/52 (50%)

Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL 1129
            EW+ NG+ +    R +T  +     L IA VRAED G YT    +    A+L
Sbjct: 5441 EWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAEL 5492



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 5/104 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   + NIV  E  +  FEC V  S D  + + W+     L    +Y   +D     + I
Sbjct: 5501 FTKRIQNIVVSEHQSATFECEV--SFDDAI-VTWYKGPTELTESQKYNFRNDGRCHYMTI 5557

Query: 2836 THTYEEDSGIYTCKA-TNSKGSATTSGSLRCTGDKNIYFDTQHP 2878
             +   +D G+Y+  A    +G A ++  L  T  K I  + + P
Sbjct: 5558 HNVTPDDEGVYSVIARLEPRGEARSTAELYLT-TKEIKLELKPP 5600



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 10/100 (10%)

Query: 3691 KPNPPRFTVEIKDNIDVPE---GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            K  P +F  EIKD I       G    F+C V P    T    W  +G       +   +
Sbjct: 7798 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFI 7854

Query: 3748 NDFGFIALDIDYIYARDAGEYTC--RATNKWGSATTTAKI 3785
             D     L I  +   DAGEYTC  R  NK    T+TAK+
Sbjct: 7855 ADGKDRKLHIIDVQLSDAGEYTCVLRLGNK--EKTSTAKL 7892



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 910  EFKTPIKDQISIKE---GGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            +F   IKD I  +    G  A FE  + P   ST    W+KDG  +  S +     +   
Sbjct: 7803 KFVKEIKDIILTESEFVGSSAIFECLVSP---STAITTWMKDGSNIRESPKHRFIADGKD 7859

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              L I  V + DAG YTC       + T++A L +
Sbjct: 7860 RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV 7894



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%)

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
            G SA FE  V P + +T    W  +G  I  + + +   D     L I  V+  D+G YT
Sbjct: 7820 GSSAIFECLVSPSTAITT---WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYT 7876

Query: 1118 VVARNAAGEAQLSASMTVE 1136
             V R    E   +A + VE
Sbjct: 7877 CVLRLGNKEKTSTAKLVVE 7895


>AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform
            protein.
          Length = 1294

 Score =  143 bits (347), Expect = 1e-32
 Identities = 75/200 (37%), Positives = 107/200 (53%), Gaps = 4/200 (2%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP      Q V V SG+  R    ++G     + W K  + +    + K L +   YTLL
Sbjct: 794  PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 853

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            ++EA+P+D+  Y C A N  G A   A   V +P   +   P  +    PP II PL+D 
Sbjct: 854  LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP---EVVSPDQEMPVYPPAIITPLQDT 910

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            + +EGQ   F C++ G  L  V WY  DK IKPS++F+M++  D Y L I+EA+PEDEG 
Sbjct: 911  VTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 969

Query: 4693 YKCVAYNSAGRVTVAAKLKV 4712
            Y  VA N+ G+V+  A L +
Sbjct: 970  YTFVASNAVGQVSSTANLSL 989



 Score =  136 bits (329), Expect = 2e-30
 Identities = 116/406 (28%), Positives = 183/406 (45%), Gaps = 44/406 (10%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F K ++  +V E ++A FE E   EP   ++W +++  ++ +   +I        L+I  
Sbjct: 616  FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPS 674

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              + D+  +  VA     TAK    L VE +  + R            + V V   Q   
Sbjct: 675  TRMSDAGKYTVVAGGNVSTAK----LFVEGRDVRIRS---------IKKEVQVIEKQRAV 721

Query: 4533 LDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            ++ +V     +D +W K+G ++  Q   R+K + E   + + I E    D+G+Y  VA  
Sbjct: 722  VEFEVN-EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA-- 778

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
              G  R      V+ P               PP++++ L+   V  G+   F   I G+P
Sbjct: 779  --GRNRSSVTLYVNAPE--------------PPQVLQELQPVTVQSGKPARFCAVISGRP 822

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P + WYK ++L+      +      EYTL + EAFPED   Y C A N  G  T +A L
Sbjct: 823  QPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASL 882

Query: 4711 -----KVTQPDQADNL--PA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                 +V  PDQ   +  PA +TPL+D V  EGQPA+F+ ++ S     + W  +   I 
Sbjct: 883  SVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIK 941

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +  F+M    +   L I   Y ED GT+T  A+ A GQV ++A L
Sbjct: 942  PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 987



 Score =  120 bits (290), Expect = 1e-25
 Identities = 118/489 (24%), Positives = 199/489 (40%), Gaps = 24/489 (4%)

Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITS----T 4385
            +EV     Q+ V +     D  ++  +   + +  Q Q + + V ++ I R   S    +
Sbjct: 710  KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 769

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445
            +  E    A      V   V   +PP   +++QP  V   + ARF     G P P I WY
Sbjct: 770  DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 829

Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR- 4504
            +E   +      +      +  L++ + F ED+AV+   A+N  G A  SA+L VE    
Sbjct: 830  KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 889

Query: 4505 --RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
                    + PP+     Q+   + GQ  R   +V+GT  + V W    KK++P    ++
Sbjct: 890  VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRM 948

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
             + + TY L I EAYP+D G Y  VA N+ G+    A   + + A  D+        ++ 
Sbjct: 949  TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQAL-DR-------QSSG 1000

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             ++ E  K + VA+    +   KI  K + +   ++G       + F+    +  +T   
Sbjct: 1001 KDVRESTKSQAVADSSFTKEESKISQKEIKS---FQGSSYEYEVQVFESVSQSSIHT--- 1054

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
              A  +D       + +     T  +K +  +    +       L+D+ V  G  AQF  
Sbjct: 1055 -AASVQDTQLCHTASLSQIAESTELSK-ECAKESTGEAPKIFLHLQDVTVKCGDTAQFLC 1112

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
             +       + W  EGA I E+   +    GN   L I N    D G ++C      G+ 
Sbjct: 1113 VLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGER 1172

Query: 4803 ETSAKLVVK 4811
             TSA L V+
Sbjct: 1173 TTSAVLSVE 1181



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 105/404 (25%), Positives = 168/404 (41%), Gaps = 44/404 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P + T  ++     E +   FEV  + E +   KW +    IK++   Q+ T      L 
Sbjct: 524  PIMITSMLKDINAEEKDTITFEVTVNYEGISY-KWLKNGVEIKSTDKCQMRTKKLTHSLN 582

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            IR V   D+A +  VA    G A  +A L VE +  + R  I         +++ V   +
Sbjct: 583  IRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHI---------KDIKVLEKK 629

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
                + +V+    I V W+K+ +++Q   R KI +E   + LLI      D+GKY  VA 
Sbjct: 630  RAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAG 688

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
             +   A+   E        +D    + ++     ++IE  K + V     +EF    V +
Sbjct: 689  GNVSTAKLFVE-------GRD---VRIRSIKKEVQVIE--KQRAV-----VEFE---VNE 728

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                  WYK    I      +     +   + + ISE    D G+Y  V    AGR   +
Sbjct: 729  DDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFV----AGRNRSS 784

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
              L V  P+    L  L P   + V  G+PA+F   I+ + +P I W +E  L+      
Sbjct: 785  VTLYVNAPEPPQVLQELQP---VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 841

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + +H+G    LL+   + ED   +TC A    G   TSA L V+
Sbjct: 842  KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 885



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 101/420 (24%), Positives = 166/420 (39%), Gaps = 34/420 (8%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP      ++   ++G  A+F+ ++ G    V SW  K   +     + M   E T    
Sbjct: 900  PPAIITPLQDTVTSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFEDT--YQ 956

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I +  P DEG YT  A N  G+   +  +  E               + V E+ + +A
Sbjct: 957  LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSG-----KDVRESTKSQA 1011

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE--- 247
                 +T E+S+ +QK   +      S+ +++V  FE      +    S+    +     
Sbjct: 1012 VADSSFTKEESKISQKEIKSF---QGSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTAS 1068

Query: 248  -SDVQISTEIDRSLGPVSP---PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             S +  STE+ +     S    PKI    ++  ++ G  AQF   L  +    VTW   G
Sbjct: 1069 LSQIAESTELSKECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEG 1128

Query: 304  QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYV 363
             ++  S + +     N   L + N Q  D G Y+ +  N  G   TS  L+VE   ES +
Sbjct: 1129 AKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESIL 1188

Query: 364  QDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEV 423
             ++             E+ IE+  KA AP   +  +  +V  G + +F C +   P    
Sbjct: 1189 HER------------IEQEIEMEMKA-APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRF 1235

Query: 424  TWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             WF   R+I +  + K  +  S    +L I    + D G  TC A N+ G  +    L V
Sbjct: 1236 QWFKAGREIYE--SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 74/281 (26%), Positives = 116/281 (41%), Gaps = 35/281 (12%)

Query: 3643 VSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETL---HKREEITIEDEKPNPPRFTV 3699
            +    QV+ R   ++E ++   F S T      E T      R  +T+    P PP+   
Sbjct: 740  IEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQ 799

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
            E++  + V  G P  F C V   G P  +I W+   +  +TG +   L+D     L +  
Sbjct: 800  ELQP-VTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE 856

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
             +  DA  YTC A N +G ATT+A           L  ++P+ +S +             
Sbjct: 857  AFPEDAAVYTCEAKNDYGVATTSAS----------LSVEVPEVVSPD------------- 893

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
             +E P+   PP  IT ++     E +  RF+CRV   +   L++ WY   K +     +R
Sbjct: 894  -QEMPVY--PPAIITPLQDTVTSEGQPARFQCRVSGTD---LKVSWYSKDKKIKPSRFFR 947

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
                     L+I   Y ED G Y   A N  G+  + A +S
Sbjct: 948  MTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 988



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 106/441 (24%), Positives = 168/441 (38%), Gaps = 41/441 (9%)

Query: 4387 TTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            TT      +  E V      P  PP     +Q     E + ARF+    G  L  + WY 
Sbjct: 877  TTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYS 935

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR-- 4504
            ++  IK S  F++  F     L I + + ED   +  VA N  G    +ANL +E +   
Sbjct: 936  KDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALD 995

Query: 4505 RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE 4564
            RQ  G  V  S    A    V      + ++K++  K I  +    G   + +++   + 
Sbjct: 996  RQSSGKDVRESTKSQA----VADSSFTKEESKIS-QKEIKSF---QGSSYEYEVQ---VF 1044

Query: 4565 EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPE 4624
            E  + + +   A  QD+      +++   E         S   +K+  K  T  A   P+
Sbjct: 1045 ESVSQSSIHTAASVQDTQLCHTASLSQIAE---------STELSKECAKESTGEA---PK 1092

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
            I   L+D  V  G   +F C +       V W      I+ S+  + S+  +   L I  
Sbjct: 1093 IFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICN 1152

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKL------------KVTQPDQADNLPALTPLRDIVV 4732
                D+G Y C+ +N  G  T +A L            ++ Q  + +   A    R I  
Sbjct: 1153 VQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEMKAAPVIKRKIEP 1212

Query: 4733 YE---GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
             E   G  A+F  +I S      QW + G  I E+    +      + L I  T   D G
Sbjct: 1213 LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCG 1272

Query: 4790 TFTCRATTAAGQVETSAKLVV 4810
             +TC+A+   G V  +A L V
Sbjct: 1273 EYTCKASNEYGSVSCTATLTV 1293



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 68/233 (29%), Positives = 98/233 (42%), Gaps = 27/233 (11%)

Query: 3554 SGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG 3613
            +G  P+      D+ +    +A F C L   +DS + V W H G  +    R+K   +  
Sbjct: 1087 TGEAPKIFLHLQDVTVKCGDTAQFLCVL--KDDSFIDVTWTHEGAKIEESERLKQSQNGN 1144

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ 3673
               L I  V   D GLY+C   N  GE T S  L V+G                  ESI 
Sbjct: 1145 IQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEG----------------APESI- 1187

Query: 3674 KLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH 3733
                 LH+R E  IE E    P    +I + ++V  G    F C ++    P +R  WF 
Sbjct: 1188 -----LHERIEQEIEMEMKAAPVIKRKI-EPLEVALGHLAKFTCEIQSA--PNVRFQWFK 1239

Query: 3734 NGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             GR      +    +     +L+I      D GEYTC+A+N++GS + TA +T
Sbjct: 1240 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT 1292



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 98/399 (24%), Positives = 165/399 (41%), Gaps = 52/399 (13%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            KK +     E+    FEV    + +P +KW+ +N  IK S   ++ +      L+++ + 
Sbjct: 355  KKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 413

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
              D+  + AV     G  +C A L VE               T T +N+ V   +    +
Sbjct: 414  PSDAGEYTAVV----GQLECKAKLFVETLH-----------ITKTMKNIEVPETKTASFE 458

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +V+    +   WLKNG +++   + KI+ +   + L+I+    +DS +Y  V     G 
Sbjct: 459  CEVSHFN-VPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGN 513

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V+                 P  I   LKD    E   I F   +  + + + 
Sbjct: 514  DQVSATLTVT-----------------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SY 555

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W K    IK +   QM      ++L I      D  DY  V    AG+ T  A L V  
Sbjct: 556  KWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFV----AGKATSTATLYV-- 609

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
              +A ++     ++DI V E + A F+ ++ S+   T+QW+++   +  T   ++  E  
Sbjct: 610  --EARHIEFRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 666

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               LLI +T   D G +T     A G V T AKL V+ +
Sbjct: 667  VHRLLIPSTRMSDAGKYT---VVAGGNVST-AKLFVEGR 701



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 65/249 (26%), Positives = 111/249 (44%), Gaps = 24/249 (9%)

Query: 1688 LNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWL 1747
            L+Q+ ++++  +  A++    +AP   + ++D+ V     A F   L    D  + V W 
Sbjct: 1069 LSQIAESTELSKECAKEST-GEAPKIFLHLQDVTVKCGDTAQFLCVL--KDDSFIDVTWT 1125

Query: 1748 RNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
              G  IE S RL    +     L +  V   D G Y+C   N+ GE  TS+ L V     
Sbjct: 1126 HEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSV----- 1180

Query: 1808 LQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECR 1867
               E   ES L   +++E        +++E+ +  AP    ++  P +++ G  A + C 
Sbjct: 1181 ---EGAPESILH--ERIE--------QEIEMEMKAAPVIKRKIE-PLEVALGHLAKFTCE 1226

Query: 1868 IEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
            I+  P  N+R +W+  G+ +    +    +    ++L+IL     D GEYTCKA N  G 
Sbjct: 1227 IQSAP--NVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 1284

Query: 1928 AVSSIRLNV 1936
               +  L V
Sbjct: 1285 VSCTATLTV 1293



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 76/294 (25%), Positives = 127/294 (43%), Gaps = 41/294 (13%)

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580
            ++VNV  G    L+ KV+      V W  N ++++PD R + + +     L+I   +  D
Sbjct: 8    KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASD 67

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
             G Y+ +        R +  C +S+   K               II  L+D    E Q +
Sbjct: 68   EGPYKLIV------GRVETNCNLSVEKIK---------------IIRGLRDLTCTETQNV 106

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
             F  ++    +  V W   DK IKPS  +++      Y L +     +DEG Y   A  +
Sbjct: 107  VFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGEN 165

Query: 4701 --AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
              +G++TVA                  PL D  V E Q A F+ ++ +      +WLR+G
Sbjct: 166  ITSGKLTVAGGA------------ISKPLTDQTVAESQEAVFECEVANPDSKG-EWLRDG 212

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              +P T + +   +G+   L+I  T  +D G +T +  T+    +TSAKL V++
Sbjct: 213  KHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKVEA 262



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 97/377 (25%), Positives = 155/377 (41%), Gaps = 47/377 (12%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            GR     ++ K+ V + E Q A  E  +    +  +   W+ +G  I    + R  Y   
Sbjct: 700  GRDVRIRSIKKE-VQVIEKQRAVVEFEV---NEDDVDAHWYKDGIEINFQVQERHKYVVE 755

Query: 3105 MVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
              +  + I  T+ +D+G Y+  A    G+   SV L     +  + P+    +Q +  ++
Sbjct: 756  RRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV---NAPEPPQVLQELQPVT-VQ 807

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G+ A F C V+    P  KI WY   Q +    + K + D     L +      D+  Y
Sbjct: 808  SGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVY 865

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282
             C A N YG   T A+++                     E+  +    Q+ P      PP
Sbjct: 866  TCEAKNDYGVATTSASLSV--------------------EVPEVVSPDQEMP----VYPP 901

Query: 3283 KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
              IT +QD T   EGQ A F+ R   V   DLKV W+   KK+     +R         L
Sbjct: 902  AIITPLQD-TVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQL 957

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLED 3402
            +I   Y E+ G Y  VA+N +G+ S+ ANL   S E   LD Q          K Q + D
Sbjct: 958  EIAEAYPEDEGTYTFVASNAVGQVSSTANL---SLEVQALDRQSSGKDVRESTKSQAVAD 1014

Query: 3403 SMVRRKDTSVEEEKGKA 3419
            S   ++++ + +++ K+
Sbjct: 1015 SSFTKEESKISQKEIKS 1031



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 59/218 (27%), Positives = 94/218 (43%), Gaps = 22/218 (10%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP++ Q+ +   +Q G  A+F   +SG P+P+++W+K  Q L    K + +      TL 
Sbjct: 794 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 853

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +      D+  YT  A+N  G   TS  L+VE P E    DQ                  
Sbjct: 854 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP-EVVSPDQEM---------------- 896

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                  P  +   QD   +EG+  RF CRV+G    +V+W+  D++I+     ++   E
Sbjct: 897 ---PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFE 952

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
              + L I      D G  T VA N  G+ +    L++
Sbjct: 953 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 989



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 59/245 (24%), Positives = 109/245 (44%), Gaps = 33/245 (13%)

Query: 1831 QRREDVEVAVN--QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
            + R  V + VN  + P+ + +L  P  +  G+ A +   I   P P  ++ WY   ++L 
Sbjct: 780  RNRSSVTLYVNAPEPPQVLQELQ-PVTVQSGKPARFCAVISGRPQP--KISWYKEEQLLS 836

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
            +G + +  +D     L ++  + ED+  YTC+A N+ G A +S  L+V+  E +      
Sbjct: 837  TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVS----- 891

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008
                                 D    V  P    P+++   +EG P   +     V+   
Sbjct: 892  --------------------PDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTD 928

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            ++V WY   + ++    F+ T       L+I  AY ED GTY   A+NAVG+  +T+++ 
Sbjct: 929  LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 988

Query: 2069 VDAKS 2073
            ++ ++
Sbjct: 989  LEVQA 993



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 71/282 (25%), Positives = 119/282 (42%), Gaps = 35/282 (12%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E PQ  + ++   V  G P    A ++    P  ++ WY   + +  G + K  +D    
Sbjct: 793  EPPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 850

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L ++ A+ ED   Y C+A N  G A T++S+ V                    E+ +  
Sbjct: 851  TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV--------------------EVPEVV 890

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
             P   ++E P   P  +T L       EG  A F+CRV   +   L + W+   +KI+  
Sbjct: 891  SP---DQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSGTD---LKVSWYSKDKKIKPS 943

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN 2215
              +R T       L+I   Y ED GTY   A+N +G+  +T  L +       LD Q  +
Sbjct: 944  RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQ---ALDRQ-SS 999

Query: 2216 GLEKIRQLEAQG-HSTRIEVEEPKISPPRFVTELRGTTHVFE 2256
            G +     ++Q    +    EE KIS  + +   +G+++ +E
Sbjct: 1000 GKDVRESTKSQAVADSSFTKEESKIS-QKEIKSFQGSSYEYE 1040



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 70/288 (24%), Positives = 117/288 (40%), Gaps = 24/288 (8%)

Query: 3089 KTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS-VKLECVDKSKGQ 3147
            K+ + S     V  F  V    + T  +   T  C   +    AE + +  EC  +S G+
Sbjct: 1030 KSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGE 1089

Query: 3148 KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV 3207
             P+   H+Q++  +K G +A F C +   DD  + + W H G  +  S R+K   +    
Sbjct: 1090 APKIFLHLQDVT-VKCGDTAQFLCVLK--DDSFIDVTWTHEGAKIEESERLKQSQNGNIQ 1146

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQ 3267
             L I   Q  D G Y C  +N  GE  T A ++  G          P+S+   R  + ++
Sbjct: 1147 FLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEG---------APESILHERIEQEIE 1197

Query: 3268 GAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPH 3327
               +  P          I +  +  ++  G  A F   +     P+++ +WF  G+++  
Sbjct: 1198 MEMKAAP---------VIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYE 1246

Query: 3328 GHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
              +        I  L+IL     + GEY C A+N+ G  S  A L  T
Sbjct: 1247 SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 1294



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 67/247 (27%), Positives = 99/247 (40%), Gaps = 23/247 (9%)

Query: 2089 QELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHN 2148
            Q  E  E  K   +E  G+ P     L  +  +K GD A F C ++  +D  + + W H 
Sbjct: 1071 QIAESTELSKECAKESTGEAPKIFLHLQDV-TVKCGDTAQFLCVLK--DDSFIDVTWTHE 1127

Query: 2149 GQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII 2208
            G KI    R + + +     L I      D G Y C   N  GE   +  L V G    I
Sbjct: 1128 GAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESI 1187

Query: 2209 LDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEP 2268
            L        E+I Q E +       V + KI P            V  G  A F C+++ 
Sbjct: 1188 LH-------ERIEQ-EIEMEMKAAPVIKRKIEP----------LEVALGHLAKFTCEIQS 1229

Query: 2269 VHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
               PN+R +++  G+ +  + +  I       SL+I      D GEY+ KA N  G  + 
Sbjct: 1230 A--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSC 1287

Query: 2329 AISMTVT 2335
              ++TVT
Sbjct: 1288 TATLTVT 1294



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 55/184 (29%), Positives = 78/184 (42%), Gaps = 28/184 (15%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            K+ W+K  Q ++ G + + +HD     L +I+   ED+ +YTC A N  G    S  L+ 
Sbjct: 825  KISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 884

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
                ++V   Q                        E+    P   T L++    EGQ A 
Sbjct: 885  E-VPEVVSPDQ------------------------EMPVYPPAIITPLQDTVTSEGQPAR 919

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656
            F+ R   VS   LKV WY  +K +K    F  T       L+I    PED GTYT  A N
Sbjct: 920  FQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASN 976

Query: 1657 ALGE 1660
            A+G+
Sbjct: 977  AVGQ 980



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 74/279 (26%), Positives = 117/279 (41%), Gaps = 41/279 (14%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P     ++ + V   + A F A  +  G P+ ++ W +    +    +   +HD    
Sbjct: 793  EPPQVLQELQPVTVQSGKPARFCA--VISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 850

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L +    PED+  YTC A N+ G A TS        ASL +E     +           
Sbjct: 851  TLLLIEAFPEDAAVYTCEAKNDYGVATTS--------ASLSVEVPEVVS----------- 891

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
                  D E+ V   P  IT L   T  SEGQ A ++CR+      +++V WY   K ++
Sbjct: 892  -----PDQEMPV-YPPAIITPLQD-TVTSEGQPARFQCRVS---GTDLKVSWYSKDKKIK 941

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
                +R +       L+I   Y ED G YT  A N +GQ  S+  L+++  +++ R S  
Sbjct: 942  PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE-VQALDRQSSG 1000

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFG-KPIKN 1986
            +   E        S   +AV D SF  E+ +   K IK+
Sbjct: 1001 KDVRE--------STKSQAVADSSFTKEESKISQKEIKS 1031



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 59/207 (28%), Positives = 82/207 (39%), Gaps = 10/207 (4%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P   L  Q+V V  G   +    +     IDV W   G K++   R K  +      L I
Sbjct: 1091 PKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTI 1150

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVS-LPAT------KDKPKPQTKAANAPPEII 4626
                  D G Y C+  N  GE    A   V   P +      + + + + KAA      I
Sbjct: 1151 CNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEMKAAPVIKRKI 1210

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
            EPL+   VA G   +F+C+I   P    QW+K  + I  S    +  +    +L I    
Sbjct: 1211 EPLE---VALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQ 1267

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
              D G+Y C A N  G V+  A L VT
Sbjct: 1268 VVDCGEYTCKASNEYGSVSCTATLTVT 1294



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 48/195 (24%), Positives = 80/195 (41%), Gaps = 10/195 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           PQ ++  Q   V  GK  RF   ++GRP P+++W+  ++ +   +  K L ++   + L+
Sbjct: 795 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL-HDGQEYTLL 853

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLN-----VIEKEQ---VVAPKFVERFSTLNVR 503
           +      D+ V TC A+N  G       L+     V+  +Q   V  P  +         
Sbjct: 854 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 913

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
           EG+P     R  GT   +++W      I P+   R+        L+I  A   D   Y  
Sbjct: 914 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 972

Query: 564 TAQNVAGSTATRARL 578
            A N  G  ++ A L
Sbjct: 973 VASNAVGQVSSTANL 987



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 81/331 (24%), Positives = 128/331 (38%), Gaps = 42/331 (12%)

Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNH------DSGEYVCRAYNKYGEDFTRATINC 3241
            +G+ +R ST+ + V+D  F   +   +Q         S EY  + +    +       + 
Sbjct: 999  SGKDVRESTKSQAVADSSFTKEESKISQKEIKSFQGSSYEYEVQVFESVSQSSIHTAASV 1058

Query: 3242 YGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAH 3301
                  +  SL    +A+  EL S + A++ T      E PK    +QDVT    G +A 
Sbjct: 1059 QDTQLCHTASLS--QIAESTEL-SKECAKEST-----GEAPKIFLHLQDVTVKC-GDTAQ 1109

Query: 3302 FEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATN 3361
            F   L   DD  + V W + G K+    R +   +  I  L I      + G Y C+  N
Sbjct: 1110 FLCVLK--DDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHN 1167

Query: 3362 KLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPV 3421
              G  +T A L                 +EG  E +      +  R +  +E E   APV
Sbjct: 1168 DCGERTTSAVL----------------SVEGAPESI------LHERIEQEIEMEMKAAPV 1205

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
                +  +E +  G  A F   +     PN++ +W+  G+ +    +           LE
Sbjct: 1206 IKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLE 1262

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            I  T   D GEY C+A N YG    TA++ V
Sbjct: 1263 ILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 51/192 (26%), Positives = 83/192 (43%), Gaps = 26/192 (13%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI W+K    L+TG + K   D    TL +     +D+ +YTC+A N  G A ++AS
Sbjct: 822  PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 881

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            + +E     + E + PD    +                       I+ L + V  EG   
Sbjct: 882  LSVE-----VPEVVSPDQEMPV------------------YPPAIITPLQDTVTSEGQPA 918

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851
             F+C V  +    LK+ W+  +K +     ++ T       L+I   Y ED G YT  A+
Sbjct: 919  RFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVAS 975

Query: 2852 NSKGSATTSGSL 2863
            N+ G  +++ +L
Sbjct: 976  NAVGQVSSTANL 987



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 68/266 (25%), Positives = 104/266 (39%), Gaps = 28/266 (10%)

Query: 1539 TTDIVRSTQ--NEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
            T   V+ TQ  + A L QI    + SK    +   E T +AP     L++V +K G  A 
Sbjct: 1054 TAASVQDTQLCHTASLSQIAESTELSK----ECAKESTGEAPKIFLHLQDVTVKCGDTAQ 1109

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656
            F    +   D+ + V W H    ++   R  ++ N     L I +    D G Y+C   N
Sbjct: 1110 F--LCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHN 1167

Query: 1657 ALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMP 1716
              GE  TS +  V       L  + E       ++E   K             APV    
Sbjct: 1168 DCGERTTSAVLSVEGAPESILHERIE------QEIEMEMK------------AAPVIKRK 1209

Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVN 1776
            ++ + VA    A F   +     P +R +W + G  I  S++ +        +L +    
Sbjct: 1210 IEPLEVALGHLAKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQ 1267

Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFV 1802
              D G YTC+A NE G    ++TL V
Sbjct: 1268 VVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 94/396 (23%), Positives = 156/396 (39%), Gaps = 52/396 (13%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            ++   V E  +A  E +     +  +KWY  +  IK     Q     TK  L+I +    
Sbjct: 7    LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 66

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D   +  +     G  + + NL VE K +  RG           +++  T  Q V  + +
Sbjct: 67   DEGPYKLIV----GRVETNCNLSVE-KIKIIRG----------LRDLTCTETQNVVFEVE 111

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            ++ +  IDV W    K+++P  + KI      Y L +L     D GKY       AGE  
Sbjct: 112  LSHSG-IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFY----AGENI 166

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
               +  V                 A   I +PL D+ VAE Q   F C+ V  P    +W
Sbjct: 167  TSGKLTV-----------------AGGAISKPLTDQTVAESQEAVFECE-VANPDSKGEW 208

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  K +  +   +      +  L I+    +D G+Y    Y  A   T +AKLKV    
Sbjct: 209  LRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY---TYKVATSKT-SAKLKV---- 260

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
              + +     L+++ V E Q A F  ++T      +QW++ G ++     + +  +G   
Sbjct: 261  --EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIY 318

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             L I N    D   +  R     G++  SA+L V++
Sbjct: 319  SLRIKNCAIVDESVYGFR----LGRLGASARLHVET 350



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 22/240 (9%)

Query: 359  TESYVQDQRSQYITDTQQ--RETEERIEISEKAL--APQFVKVCQDRDVTEGKMTRFDCR 414
            T + VQD +  +     Q    TE   E ++++   AP+     QD  V  G   +F C 
Sbjct: 1054 TAASVQDTQLCHTASLSQIAESTELSKECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCV 1113

Query: 415  VTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGE 473
            +    + +VTW     +I +  + ++  +++GN   L I NV L D G+ +C+  N  GE
Sbjct: 1114 LKDDSFIDVTWTHEGAKIEE--SERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGE 1171

Query: 474  TAFQCRLNV---------------IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
                  L+V               IE E   AP    +   L V  G            P
Sbjct: 1172 RTTSAVLSVEGAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAP 1231

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              R  W K G  I  + +  I +    S+L+I R +  D   Y C A N  GS +  A L
Sbjct: 1232 NVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 1291



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 101/469 (21%), Positives = 176/469 (37%), Gaps = 59/469 (12%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            ++ +W  NG +I S ++ Q        +L+I +V   D+  YT VA  A   A L     
Sbjct: 553  ISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEAR 612

Query: 1135 -VETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGK 1193
             +E R  I    +     EK R + E +  EP   ++ +   + +    +++   + + K
Sbjct: 613  HIEFRKHIKDIKV----LEKKRAMFECEVSEPDITVQWMKDDQEL---QITDRIKIQKEK 665

Query: 1194 NIHL----ECRLEPMGDPTM-------RVEWFHNGRSVTVGSRFKTYYDFGFVALDI--- 1239
             +H       R+   G  T+         + F  GR V + S  K           +   
Sbjct: 666  YVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFE 725

Query: 1240 IHATSADTGEYT--VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARR 1297
            ++    D   Y   +     +   H   + R I R   +++T+   A E   +   A R 
Sbjct: 726  VNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRM-FISETRQSDAGEYTFV---AGRN 781

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
               V   +   + PQ  + L  +    G      C +   G    ++ W+   + + TG 
Sbjct: 782  RSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGF 839

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSG 1417
            + +  ++     L L+  +PED+ VYTC+A N  G A TS +L V   + +  + + P  
Sbjct: 840  KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP-- 897

Query: 1418 LEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK 1477
                                    + P  +  P       EGQ   F+C+   V+ ++LK
Sbjct: 898  ------------------------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLK 930

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            V W+   + +     FR         L+I +   ED G YT  A N VG
Sbjct: 931  VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVG 979



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 50/197 (25%), Positives = 86/197 (43%), Gaps = 30/197 (15%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W+   Q +  G + +  HD     L ++  + ED+  Y C+A N  G A  + +
Sbjct: 822  PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 881

Query: 2199 LKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            L V     +  D + P                        + PP  +T L+ T    EG+
Sbjct: 882  LSVEVPEVVSPDQEMP------------------------VYPPAIITPLQDTV-TSEGQ 916

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT-FDFGYVSLDIQHCVPEDAGEYSV 2317
             A F+C+V      +L++ +Y   K ++ +  F +T F+  Y  L+I    PED G Y+ 
Sbjct: 917  PARFQCRVSGT---DLKVSWYSKDKKIKPSRFFRMTQFEDTY-QLEIAEAYPEDEGTYTF 972

Query: 2318 KAINALGHCTSAISMTV 2334
             A NA+G  +S  ++++
Sbjct: 973  VASNAVGQVSSTANLSL 989



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 62/255 (24%), Positives = 107/255 (41%), Gaps = 34/255 (13%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++ G  A F A +   G    ++ W K+ + +    +     +     L +      D
Sbjct: 804  VTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 861

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK 1038
            A  YTC A N  G ATTSA+L++   + +  + + P                        
Sbjct: 862  AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP------------------------ 897

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
                P  + PL+ T    EGQ A F+ RV   S   + V WY   K+I  +   +     
Sbjct: 898  -VYPPAIITPLQDT-VTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRMTQFE 952

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRH-- 1156
                L+IA    ED G YT VA NA G+   +A++++E + ++D  S  + + E T+   
Sbjct: 953  DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQ-ALDRQSSGKDVRESTKSQA 1011

Query: 1157 IEESKFVEPMYQIEE 1171
            + +S F +   +I +
Sbjct: 1012 VADSSFTKEESKISQ 1026



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 68/279 (24%), Positives = 122/279 (43%), Gaps = 32/279 (11%)

Query: 1793 EAVTSSTLFVQSKASLQ-LESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLN 1851
            E+V+ S+  + + AS+Q  +  H ++L +I +  + S+   +E    +  +AP+    L 
Sbjct: 1045 ESVSQSS--IHTAASVQDTQLCHTASLSQIAESTELSKECAKE----STGEAPKIFLHLQ 1098

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
              T +  G +A + C ++   D  + V W   G  ++   R + S +     L I  V  
Sbjct: 1099 DVT-VKCGDTAQFLCVLKD--DSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQL 1155

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ-SKESIIRDSQHESALEKIQYLEDDSRYKRAVQD 1970
             D G Y+C   N+ G+  +S  L+V+ + ESI+    HE   ++I     +   K A   
Sbjct: 1156 VDQGLYSCIVHNDCGERTTSAVLSVEGAPESIL----HERIEQEI-----EMEMKAA--- 1203

Query: 1971 DSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY 2030
                   P   + I+  EV  GH       +   + P +R +W+  GR + +  +     
Sbjct: 1204 -------PVIKRKIEPLEVALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKCSIRS 1254

Query: 2031 DFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                 +L+IL     D G Y CKA+N  G    T+++ V
Sbjct: 1255 SKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 92/397 (23%), Positives = 156/397 (39%), Gaps = 53/397 (13%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            +K +    V E ++A FE E    P    +W R+   +  + + +  +   K  LII   
Sbjct: 179  SKPLTDQTVAESQEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAAT 237

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             ++D   +      +  T+K SA L VE  +              T +N+ VT  Q    
Sbjct: 238  KLDDIGEYTY----KVATSKTSAKLKVEAVK-----------IKKTLKNLTVTETQDAVF 282

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              ++T      V W+KNG  ++ + +  I  +   Y+L I      D   Y         
Sbjct: 283  TVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGA 342

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR   E V                     +II+  KD    E   + F   +    +P 
Sbjct: 343  SARLHVETV---------------------KIIKKPKDVTALENATVAFEVSVSHDTVP- 380

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            V+W+  +  IKPS   ++      + L +    P D G+Y  V     G++   AKL V 
Sbjct: 381  VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFV- 435

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
                 + L     +++I V E + A F+ +++    P++ WL+ G  I  +  F+++ +G
Sbjct: 436  -----ETLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG 489

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                L+I NT  ED+  +    T   G  + SA L V
Sbjct: 490  KLHQLIIMNTSTEDSAEY----TFVCGNDQVSATLTV 522



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 72/256 (28%), Positives = 104/256 (40%), Gaps = 34/256 (13%)

Query: 2204 HRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFE 2263
            HR  I +T+  +  E          S  + V  P+  PP+ + EL+  T V  GK A F 
Sbjct: 759  HRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPE--PPQVLQELQPVT-VQSGKPARF- 814

Query: 2264 CQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINAL 2323
            C V     P  +I +Y   + L +  +     D    +L +    PEDA  Y+ +A N  
Sbjct: 815  CAVISGR-PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 873

Query: 2324 GHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQ 2383
            G  T++ S++V            PE +   +E+        P  P       P    PLQ
Sbjct: 874  GVATTSASLSVEV----------PEVVSPDQEM--------PVYP-------PAIITPLQ 908

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            +     EGQ A F CR   V    LKV W+  +K I+ S     T       + I+    
Sbjct: 909  DTVT-SEGQPARFQCR---VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 964

Query: 2444 EDEGVYMCRASNLLGE 2459
            EDEG Y   ASN +G+
Sbjct: 965  EDEGTYTFVASNAVGQ 980



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 67/233 (28%), Positives = 97/233 (41%), Gaps = 35/233 (15%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PPQ +  L+ VT   G    F   I   G P  KI W K  Q +    +   +      +
Sbjct: 794 PPQVLQELQPVTVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
           L ++    +D+  YTC A +  GVA T A L V          + PE +   Q++  Y  
Sbjct: 852 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV----------EVPEVVSPDQEMPVYP- 900

Query: 756 YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                         P  I PLQD     EG+ A F+ +   VS   ++V WY   + I  
Sbjct: 901 --------------PAIITPLQDT-VTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 942

Query: 816 SS--RITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           S   R+T  F   Y  L I     ED G+YT  A N +G+  STA++ +  ++
Sbjct: 943 SRFFRMTQ-FEDTY-QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQA 993



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 64/234 (27%), Positives = 104/234 (44%), Gaps = 27/234 (11%)

Query: 904  EST-QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            EST + P+    ++D +++K G  A F   L+   DS + V W  +G  +E S R+    
Sbjct: 1085 ESTGEAPKIFLHLQD-VTVKCGDTAQFLCVLKD--DSFIDVTWTHEGAKIEESERLKQSQ 1141

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            N     LTI +V + D G Y+C  +N  G+ TTSA L++             G  E I +
Sbjct: 1142 NGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSV------------EGAPESILH 1189

Query: 1023 LEDASRYSKRTEEEVKITQK-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081
                 R  +  E E+K      R + PL    ++  G  A F   +  QS   +  +W+ 
Sbjct: 1190 ----ERIEQEIEMEMKAAPVIKRKIEPL----EVALGHLAKFTCEI--QSAPNVRFQWFK 1239

Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G++I  +++          +L+I   +  D G YT  A N  G    +A++TV
Sbjct: 1240 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 61/227 (26%), Positives = 99/227 (43%), Gaps = 25/227 (11%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+  + L+ VT   G    F   ++   D  + + W   G  IE S R           L
Sbjct: 1091 PKIFLHLQDVTVKCGDTAQFLCVLKD--DSFIDVTWTHEGAKIEESERLKQSQNGNIQFL 1148

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
             + ++ + D G Y+C   +  G   T AVL V            PE++ + +++E     
Sbjct: 1149 TICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGA---------PESILH-ERIE----- 1193

Query: 757  QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
               + IE +    P   R ++ L E+  G  A F  ++   S P +R +W+K GR I  S
Sbjct: 1194 ---QEIEMEMKAAPVIKRKIEPL-EVALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYES 1247

Query: 817  SRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             +  SI +  Y+ SL I+  +  D G YT +A N+ G    TA++ V
Sbjct: 1248 DK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 52/187 (27%), Positives = 80/187 (42%), Gaps = 15/187 (8%)

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
            ++I PLKD  V EG      CK+    + +V+WY  D+ IKP    Q      +  L I+
Sbjct: 2    DVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVIN 61

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                 DEG YK +     GRV     L V      + +  +  LRD+   E Q   F+ +
Sbjct: 62   RTHASDEGPYKLI----VGRVETNCNLSV------EKIKIIRGLRDLTCTETQNVVFEVE 111

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            + S     + W  +   I  +  +++   G    L + N  ++D G +    T  AG+  
Sbjct: 112  L-SHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKY----TFYAGENI 166

Query: 4804 TSAKLVV 4810
            TS KL V
Sbjct: 167  TSGKLTV 173



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 82/307 (26%), Positives = 134/307 (43%), Gaps = 46/307 (14%)

Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
           ++ K+ E   A F+ ++S  P   V W K+ Q L  +++ +I        L + +T+ SD
Sbjct: 621 KDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 679

Query: 333 SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
           +G YT++A    G  V++  L VE                D + R  ++ +++ EK  A 
Sbjct: 680 AGKYTVVA----GGNVSTAKLFVEG--------------RDVRIRSIKKEVQVIEKQRAV 721

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
              +V +D DV              +   E+ + + +R       HK +V E   H + I
Sbjct: 722 VEFEVNED-DVDAHWY---------KDGIEINFQVQER-------HKYVV-ERRIHRMFI 763

Query: 453 TNVTLSDSGVVTCVA-RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           +    SD+G  T VA RN+S  T +   +N  E  QV+     +    + V+ G+P    
Sbjct: 764 SETRQSDAGEYTFVAGRNRSSVTLY---VNAPEPPQVL-----QELQPVTVQSGKPARFC 815

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
           A   G P P+I+W K+   +    + +   DG   TL +  A   DAA Y C A+N  G 
Sbjct: 816 AVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGV 875

Query: 572 TATRARL 578
             T A L
Sbjct: 876 ATTSASL 882



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 70/304 (23%), Positives = 125/304 (41%), Gaps = 25/304 (8%)

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL 3009
            +GK + + ++ +  +D  F T +   + +++   +   +Y    + F S +         
Sbjct: 999  SGKDVRESTKSQAVADSSF-TKEESKISQKEIKSFQGSSYEYEVQVFESVSQSSIHTAAS 1057

Query: 3010 IERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYE 3069
            ++ TQ    T  L +I    + L KE  ++    TG  P+     +D+  +  G  A + 
Sbjct: 1058 VQDTQLCH-TASLSQIAESTE-LSKECAKE---STGEAPKIFLHLQDVT-VKCGDTAQFL 1111

Query: 3070 ASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKW 3129
              L    D  + + W + G  IE S R++      +  L I   +  D G YSC   N  
Sbjct: 1112 CVL--KDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDC 1169

Query: 3130 GQAEISVKL-----------ECVDKSKGQKPRFTTHI-QNIEGLKD--GQSAHFECTVVP 3175
            G+   S  L           E +++    + +    I + IE L+   G  A F C +  
Sbjct: 1170 GERTTSAVLSVEGAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQS 1229

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               P+++ +W+  G+ +  S +    S      L+I  TQ  D GEY C+A N+YG    
Sbjct: 1230 A--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSC 1287

Query: 3236 RATI 3239
             AT+
Sbjct: 1288 TATL 1291



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 54/212 (25%), Positives = 90/212 (42%), Gaps = 23/212 (10%)

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
            G +A F   ++  S + +T  W   G +I  + R++   +     L I +V+  D G+Y+
Sbjct: 1105 GDTAQFLCVLKDDSFIDVT--WTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYS 1162

Query: 1118 VVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKP 1177
             +  N  GE   SA ++VE       S +H         IE+        +IE   K+ P
Sbjct: 1163 CIVHNDCGERTTSAVLSVE---GAPESILH-------ERIEQ--------EIEMEMKAAP 1204

Query: 1178 VFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVAL 1237
            V  + +  P  V+ G      C ++    P +R +WF  GR +    +          +L
Sbjct: 1205 VIKRKI-EPLEVALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKCSIRSSKYISSL 1261

Query: 1238 DIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            +I+     D GEYT +A N  GS   +A + V
Sbjct: 1262 EILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 77/301 (25%), Positives = 120/301 (39%), Gaps = 44/301 (14%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P  +Q L  P  V  GK     C +   G P  ++ W+   + ++ G + K  +D     
Sbjct: 795  PQVLQELQ-PVTVQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 851

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L +I A   D   YT  A N  G A TSA + V E  ++V+  Q                
Sbjct: 852  LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEMP------------- 897

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
                       +  P     L +  T EG     +CR   V    ++V W+   K IK  
Sbjct: 898  -----------VYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKPS 943

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
              FR     D   L++   YPED G YT  A+N +G+ V+S A       +L LE Q   
Sbjct: 944  RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ-VSSTA-------NLSLEVQ--- 992

Query: 1417 GLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKL-EPVTDSN 1475
             L++    +D     K+  + +S   K       K I++  +G    +E ++ E V+ S+
Sbjct: 993  ALDRQSSGKDVRESTKSQAVADSSFTKEESKISQKEIKS-FQGSSYEYEVQVFESVSQSS 1051

Query: 1476 L 1476
            +
Sbjct: 1052 I 1052



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 29/104 (27%), Positives = 59/104 (56%), Gaps = 3/104 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+ + +++  TV+  +  RF   +  +  PK  I WY+  +LL +G + + ++D    +
Sbjct: 794  PPQVLQELQPVTVQSGKPARFCAVISGRPQPK--ISWYKEEQLLSTGFKCKFLHDGQEYT 851

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            L ++  + ED+  Y C A ND+G   T A++S  ++P+++  +Q
Sbjct: 852  LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQ 894



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 54/252 (21%), Positives = 103/252 (40%), Gaps = 25/252 (9%)

Query: 3669 TESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMR 3728
            T S+ ++ E+    +E   ++     P+  + ++D + V  G    F C ++   D  + 
Sbjct: 1066 TASLSQIAESTELSKECA-KESTGEAPKIFLHLQD-VTVKCGDTAQFLCVLKD--DSFID 1121

Query: 3729 IDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            + W H G       R+    +     L I  +   D G Y+C   N  G  TT+A ++  
Sbjct: 1122 VTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVE 1181

Query: 3789 AKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVR 3848
               + +L  ++ Q +      E+E        K  P++        +I+   V      +
Sbjct: 1182 GAPESILHERIEQEI------EMEM-------KAAPVIKR------KIEPLEVALGHLAK 1222

Query: 3849 FECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
            F C ++    P +R +W++ G+ +    +          SL+IL     D GEY C+A N
Sbjct: 1223 FTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASN 1280

Query: 3909 DFGEDFTKATIS 3920
            ++G     AT++
Sbjct: 1281 EYGSVSCTATLT 1292



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 49/197 (24%), Positives = 85/197 (43%), Gaps = 19/197 (9%)

Query: 2005 NDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            +D  + V W   G  +++  R K + +     L I      D G Y C   N  GE  T+
Sbjct: 1116 DDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTS 1175

Query: 2065 SSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEG 2124
            + + V+       +++  +R++  QE+E   +  P+ + +          +  LE +  G
Sbjct: 1176 AVLSVEGAP----ESILHERIE--QEIEMEMKAAPVIKRK----------IEPLE-VALG 1218

Query: 2125 DRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMC 2184
              A F C ++  + P++   WF  G++I    +          +L+IL T   D G Y C
Sbjct: 1219 HLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTC 1276

Query: 2185 KATNKLGEAVNTCTLKV 2201
            KA+N+ G    T TL V
Sbjct: 1277 KASNEYGSVSCTATLTV 1293



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 105/508 (20%), Positives = 194/508 (38%), Gaps = 58/508 (11%)

Query: 4306 GDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQ 4365
            G+ +TS  +  +     +   DQT   +++ V +     P      E    GK + +   
Sbjct: 163  GENITSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANP--DSKGEWLRDGKHLPLTNN 220

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
             +++ +    + I       +  E  +K  T +   +  V+  K     K ++   V E 
Sbjct: 221  IRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVK---IKKTLKNLTVTET 277

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            + A F VE     +  ++W +    ++++  + I    T   L I+   + D +V+    
Sbjct: 278  QDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGF-- 335

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
              R G    SA L VE  +      I  P      +N  V     V  DT       + V
Sbjct: 336  --RLGRLGASARLHVETVKI-----IKKPKDVTALENATVAFEVSVSHDT-------VPV 381

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W     +++P  +++++ E   + L++    P D+G+Y  V     G+  C A+  V  
Sbjct: 382  KWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVE- 436

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                               I + +K+  V E +   F C++    +P++ W K    I+ 
Sbjct: 437  ----------------TLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEM 479

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+ F++      + L I     ED  +Y  V     G   V+A L VT       +   +
Sbjct: 480  SEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV----CGNDQVSATLTVTP------IMITS 529

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             L+DI   E     F+  +  +   + +WL+ G  I  T   QM  +     L I N + 
Sbjct: 530  MLKDINAEEKDTITFEVTVNYE-GISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHF 588

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             D   +    T  AG+  ++A L V+++
Sbjct: 589  GDAADY----TFVAGKATSTATLYVEAR 612



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 66/289 (22%), Positives = 117/289 (40%), Gaps = 38/289 (13%)

Query: 3365 RDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTV 3424
            +D  + N +   +   +++ ++ R       +    E + V  ++ S       AP    
Sbjct: 737  KDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQ 796

Query: 3425 PLSNIE--NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI 3482
             L  ++   ++ G+ A F A ++    P  K+ WY   + L  G + +   D     L +
Sbjct: 797  VLQELQPVTVQSGKPARFCAVISGRPQP--KISWYKEEQLLSTGFKCKFLHDGQEYTLLL 854

Query: 3483 SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYS 3542
               +PED+  Y C A N+YG A T+AS+ V+    +  + ++P      I  +       
Sbjct: 855  IEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQ------ 908

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT 3602
               DT+T E   G P                 A F+CR   V+ + ++V W+   K  + 
Sbjct: 909  ---DTVTSE---GQP-----------------ARFQCR---VSGTDLKVSWYSKDKK-IK 941

Query: 3603 GSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             SR   +  F     LEI   Y  D G YT  A+N  G+ + +  L ++
Sbjct: 942  PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 990



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 63/256 (24%), Positives = 100/256 (39%), Gaps = 35/256 (13%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            + P     L+ V ++ G+ A F    +       K+ WY   + L +G +    ++    
Sbjct: 793  EPPQVLQELQPVTVQSGKPARF--CAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY 850

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTS 1695
             L ++   PED+  YTC A N  G A TS    V   + +                    
Sbjct: 851  TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVV-------------------- 890

Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
                 S   E+    P    P++D   +E Q A F+ R   V    L+V W      I+ 
Sbjct: 891  -----SPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIKP 942

Query: 1756 SN--RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA-SLQLES 1812
            S   R+T   D   + +   Y  PED GTYT  A N +G+  +++ L ++ +A   Q   
Sbjct: 943  SRFFRMTQFEDTYQLEIAEAY--PEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSG 1000

Query: 1813 QHESALQKIQQLEDSS 1828
            +      K Q + DSS
Sbjct: 1001 KDVRESTKSQAVADSS 1016



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 109/540 (20%), Positives = 201/540 (37%), Gaps = 41/540 (7%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            V+  +PP+ + ++Q  T +   +  +F C +   G P  K+ W+   + L    +   ++
Sbjct: 789  VNAPEPPQVLQELQPVT-VQSGKPARF-CAVIS-GRPQPKISWYKEEQLLSTGFKCKFLH 845

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
            D     +     +PED+  Y C A N YG+  T A +                   S+E 
Sbjct: 846  DGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASL-------------------SVE- 885

Query: 4087 IREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL 4146
            + E+     V+P+Q   E     P +   L D VT  EG+ ARF CRV+G    +V W  
Sbjct: 886  VPEV-----VSPDQ---EMPVYPPAIITPLQDTVT-SEGQPARFQCRVSGTDL-KVSWYS 935

Query: 4147 NGNTIVNGSRYKLT-YDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDD 4205
                I     +++T ++  Y  +I +    D G    +             L +  +  D
Sbjct: 936  KDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALD 995

Query: 4206 YRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEW 4265
             +   K+       +      + T+ E    ++++   QG          + + +     
Sbjct: 996  RQSSGKDVRESTKSQAVA-DSSFTKEESKISQKEIKSFQGSSYEYEVQVFESVSQSSIHT 1054

Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDN 4325
              SV+  +     +  Q  E+ ++ KE   +EST +       +   TV      ++   
Sbjct: 1055 AASVQDTQLCHTASLSQIAESTELSKECA-KESTGEAPKIFLHLQDVTVKCGDTAQFLCV 1113

Query: 4326 L--DQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEV-HVAKQKQTQKEVVGDKEITRKI 4382
            L  D   +VT      K+ +  R+       +    + +V    Q     +   +   + 
Sbjct: 1114 LKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERT 1173

Query: 4383 TSTE-TTEIEHKAQTQERVV-EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLP 4440
            TS   + E   ++   ER+  E  ++    P+  +K++P  V     A+F  E    P  
Sbjct: 1174 TSAVLSVEGAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNV 1233

Query: 4441 LIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
              +W++    I  S    I +    S L I +  V D   +   A N  G+  C+A L V
Sbjct: 1234 RFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 68/265 (25%), Positives = 109/265 (41%), Gaps = 29/265 (10%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            V DTQ        Q+ E +   +K+  ++ T  +AP+    L ++    G      C L+
Sbjct: 1058 VQDTQLCHTASLSQIAE-STELSKECAKESTG-EAPKIFLHLQDVTVKCGDTAQFLCVLK 1115

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
               D  + V W   G  I+   R + +   +   L + +V   D G+Y+C   N  GE  
Sbjct: 1116 D--DSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERT 1173

Query: 1396 TSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIEN 1455
            TS  L V    + IL        E+I+  E     K   +I     I+P           
Sbjct: 1174 TSAVLSVEGAPESILH-------ERIEQ-EIEMEMKAAPVIKRK--IEPL---------E 1214

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV-ALDIIDLIAEDS 1514
            V  G    F C+++  +  N++ +WFK G+ +    +   I    Y+ +L+I+     D 
Sbjct: 1215 VALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDC 1271

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRST 1539
            G YTC+A N  G+  VSC  T   T
Sbjct: 1272 GEYTCKASNEYGS--VSCTATLTVT 1294



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 55/237 (23%), Positives = 92/237 (38%), Gaps = 27/237 (11%)

Query: 3413 EEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF 3472
            +E  G+AP   + L ++  ++ G+ A F   L   DD  + V W   G  ++   R +  
Sbjct: 1084 KESTGEAPKIFLHLQDV-TVKCGDTAQFLCVLK--DDSFIDVTWTHEGAKIEESERLKQS 1140

Query: 3473 CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTI 3532
             +     L I      D G Y C  +N+ GE  T+A + V+G    IL  ++ + +    
Sbjct: 1141 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEI---- 1196

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592
                              E E    P        L ++    A F C +   +  ++R +
Sbjct: 1197 ------------------EMEMKAAPVIKRKIEPLEVALGHLAKFTCEI--QSAPNVRFQ 1236

Query: 3593 WFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            WF  G+ +    +    +      LEI      D G YTCKA+N +G  + +  L V
Sbjct: 1237 WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 69/275 (25%), Positives = 119/275 (43%), Gaps = 44/275 (16%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            PQ ++ LQ +  +Q G+ A F A ++    P  ++ WYK+ + ++   +   + +    +
Sbjct: 795  PQVLQELQPV-TVQSGKPARFCAVIS--GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 851

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L ++    EDA  YT  A N  G  ++T S   A+ S    ++  P+Q   +        
Sbjct: 852  LLLIEAFPEDAAVYTCEAKNDYG--VATTS---ASLSVEVPEVVSPDQEMPV-------- 898

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                               P   TP++D ++  EG  A F+ R   +  + L+V W    
Sbjct: 899  -----------------YPPAIITPLQDTVT-SEGQPARFQCR---VSGTDLKVSWYSKD 937

Query: 950  RPVEASS--RITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
            + ++ S   R+T F +     L I      D G YT  A NA+GQ +++ANL++  +   
Sbjct: 938  KKIKPSRFFRMTQFEDT--YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQ--- 992

Query: 1008 IAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQK 1042
              + Q  G   +      A   S  T+EE KI+QK
Sbjct: 993  ALDRQSSGKDVRESTKSQAVADSSFTKEESKISQK 1027



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 59/234 (25%), Positives = 92/234 (39%), Gaps = 24/234 (10%)

Query: 2357 ESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNE 2416
            ES E  K  E  +  T + P     LQ++  ++ G TA F C L    D  + V W    
Sbjct: 1074 ESTELSK--ECAKESTGEAPKIFLHLQDV-TVKCGDTAQFLCVL--KDDSFIDVTWTHEG 1128

Query: 2417 KLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQL 2476
              IE+S R+ ++ +     +TI +V+  D+G+Y C   N  GE                 
Sbjct: 1129 AKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGA----- 1183

Query: 2477 ETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVG 2536
                PE +         HER  +E + E +     +    P E+  G  A +   +    
Sbjct: 1184 ----PESIL--------HERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSA- 1230

Query: 2537 DPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             P++RF+W+  G E+    +          +L+I      D G Y CKA N  G
Sbjct: 1231 -PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYG 1283



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 70/284 (24%), Positives = 113/284 (39%), Gaps = 34/284 (11%)

Query: 719  VAETKAVLHVTPRATIERTSQ-HPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQ 777
            V E+ +   +   A+++ T   H  +L  I +  + SK    E  +E T + P+    LQ
Sbjct: 1043 VFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSK----ECAKESTGEAPKIFLHLQ 1098

Query: 778  DLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRA 837
            D+  ++ G  A F   L    D  + V W  +G  I  S R+    N     L I +++ 
Sbjct: 1099 DV-TVKCGDTAQFLCVLK--DDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQL 1155

Query: 838  EDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXX 897
             D G Y+    N  GE  ++A + V       A   I  +R  IE+              
Sbjct: 1156 VDQGLYSCIVHNDCGERTTSAVLSVEG-----APESILHER--IEQEIEM---------- 1198

Query: 898  XXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR 957
                  E    P  K  I + + +  G  A F   ++      +R +W K GR +  S +
Sbjct: 1199 ------EMKAAPVIKRKI-EPLEVALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDK 1249

Query: 958  ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +   +    +L I    V D G YTC+A N  G  + +A LT+
Sbjct: 1250 CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +  L  +  + G    F C V   R P  KI W+   + L +G + K  HD    +L + 
Sbjct: 798  LQELQPVTVQSGKPARF-CAVISGR-PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI 855

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSL 2863
              + ED+ +YTC+A N  G ATTS SL
Sbjct: 856  EAFPEDAAVYTCEAKNDYGVATTSASL 882



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 96/395 (24%), Positives = 167/395 (42%), Gaps = 34/395 (8%)

Query: 1424 LEDTSRYK-KTDIIDESVTIKPRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLK-VE 1479
            L+D   Y  K      S  +K   V   K+++N  V E Q   F  +L   T  N+K V+
Sbjct: 239  LDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL---THPNVKGVQ 295

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W KNG  +    ++         +L I +    D  +Y  R    +G    S RL    T
Sbjct: 296  WIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFR----LGRLGASARLHVE-T 350

Query: 1540 TDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599
              I++  ++   LE   V  + S  H T  V        I   S K+  + E +      
Sbjct: 351  VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEI-KPSDKHRLVSERKVHKLML 409

Query: 1600 RLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPED-SGTYTCRA--I 1655
            + I  SDA    E+      L+  ++ F ET +      +I   +PE  + ++ C     
Sbjct: 410  QNISPSDAG---EYTAVVGQLECKAKLFVETLHITKTMKNIE--VPETKTASFECEVSHF 464

Query: 1656 NALGEAVTSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV---ITQAP 1711
            N     + +G+ I  S+K  I ++ +    +      ED+++Y      D+V   +T  P
Sbjct: 465  NVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTP 524

Query: 1712 VF-TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            +  T  +KDI   E     FE   + V    +  +WL+NGV I+++++          +L
Sbjct: 525  IMITSMLKDINAEEKDTITFE---VTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSL 581

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            N++ V+  D+  YT  A    G+A +++TL+V+++
Sbjct: 582  NIRNVHFGDAADYTFVA----GKATSTATLYVEAR 612



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 46/201 (22%), Positives = 88/201 (43%), Gaps = 24/201 (11%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            K+D  + + W   G  +E+  R K + +     L + +V   D G+Y+C  +N  GE  T
Sbjct: 1115 KDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTT 1174

Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI 3057
            S+ +   S +   E   H    E +E  Q +E  ++  P  +   +              
Sbjct: 1175 SAVL---SVEGAPESILH----ERIE--QEIEMEMKAAPVIKRKIEP------------- 1212

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            ++++ G +A +   +      ++  +WF  G+ I  S +     +  +  LEIL T+  D
Sbjct: 1213 LEVALGHLAKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVD 1270

Query: 3118 SGTYSCRATNKWGQAEISVKL 3138
             G Y+C+A+N++G    +  L
Sbjct: 1271 CGEYTCKASNEYGSVSCTATL 1291



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 64/319 (20%), Positives = 119/319 (37%), Gaps = 36/319 (11%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            +Y   A R        V   + P+ L  L+    +  G+ A F A +  +      + WY
Sbjct: 773  EYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVT-VQSGKPARFCAVISGRPQ--PKISWY 829

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
               + +++  + +  HD     L +     ED+ VYT  A+N  G A  SAS++VE    
Sbjct: 830  KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 889

Query: 1141 IDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECR 1200
            +                            +E+    P  + PL +    SEG+    +CR
Sbjct: 890  VSPD-------------------------QEMPVYPPAIITPLQDTV-TSEGQPARFQCR 923

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLG- 1259
            +       ++V W+   + +     F+         L+I  A   D G YT  A N +G 
Sbjct: 924  VS---GTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ 980

Query: 1260 ---SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRA 1316
               +A+ S  V+ ++R     D +     + +         +K  +++I   Q   +   
Sbjct: 981  VSSTANLSLEVQALDRQSSGKDVRESTKSQAVADSSFTKEESKISQKEIKSFQGSSYEYE 1040

Query: 1317 LHNIETVEGTNVHLECRLQ 1335
            +   E+V  +++H    +Q
Sbjct: 1041 VQVFESVSQSSIHTAASVQ 1059



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 45/199 (22%), Positives = 84/199 (42%), Gaps = 20/199 (10%)

Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
            + D  + + W   G  +    RLK + +  +  L+I +++  D G+Y+C   N  GE  +
Sbjct: 1115 KDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTT 1174

Query: 2729 TASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEG 2788
            +A + +E       ES+  + +++   +                  V + HL        
Sbjct: 1175 SAVLSVEGAP----ESILHERIEQ--EIEMEMKAAPVIKRKIEPLEVALGHLAK------ 1222

Query: 2789 DNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LDITHTYEEDSGIYT 2847
                F C ++ +  P ++ +WF   + +    +  S     Y+S L+I  T   D G YT
Sbjct: 1223 ----FTCEIQSA--PNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYT 1275

Query: 2848 CKATNSKGSATTSGSLRCT 2866
            CKA+N  GS + + +L  T
Sbjct: 1276 CKASNEYGSVSCTATLTVT 1294



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 46/197 (23%), Positives = 72/197 (36%), Gaps = 20/197 (10%)

Query: 1206 DPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
            D  + V W H G  +    R K   +     L I +    D G Y+    N  G   TSA
Sbjct: 1117 DSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSA 1176

Query: 1266 IVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEG 1325
            ++ V    + +   + EQ IE                  + +  AP   R +  +E   G
Sbjct: 1177 VLSVEGAPESILHERIEQEIE------------------MEMKAAPVIKRKIEPLEVALG 1218

Query: 1326 TNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTC 1385
                  C +Q      +R +WF  G+ I    +          +L++L     D G YTC
Sbjct: 1219 HLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTC 1276

Query: 1386 QATNQLGEAVTSCALRV 1402
            +A+N+ G    +  L V
Sbjct: 1277 KASNEYGSVSCTATLTV 1293



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 54/238 (22%), Positives = 94/238 (39%), Gaps = 35/238 (14%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PK    ++  TV+  +  +F C +  K+D  + + W   G  +    R +   +     L
Sbjct: 1091 PKIFLHLQDVTVKCGDTAQFLCVL--KDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFL 1148

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949
             I  V   D G Y C   ND GE  T A +S +  P+ IL  ++           + E  
Sbjct: 1149 TICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERI-----------EQEIE 1197

Query: 3950 IKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEW 4009
            ++   + V   + +  +V      +F  +IQS                AP    N++ +W
Sbjct: 1198 MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQS----------------AP----NVRFQW 1237

Query: 4010 FFNGKPLLHKNRFTPIYDFGYV-AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
            F  G+ +   ++ + I    Y+ ++        D GEY C+A+N YG     A +  T
Sbjct: 1238 FKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 1294



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 69  PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
           P PP   Q  +      G  A+F   + G P P +SW +++  L    K    ++ Q  +
Sbjct: 792 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQ--E 849

Query: 129 VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            +LL+ +  P D   YTC A+N YG A  S  +  E
Sbjct: 850 YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 885



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 37/129 (28%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 2904 PDTEYPK-PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            PD E P  P  II    +    EGQ    + +V   +  DLK+ WY   K ++    F++
Sbjct: 892  PDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV---SGTDLKVSWYSKDKKIKPSRFFRM 948

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022
            T       L++ + Y  D G YT  A N  G+   SST   + +   ++R    K     
Sbjct: 949  TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ--VSSTANLSLEVQALDRQSSGKDVRES 1006

Query: 3023 EKIQNLEDS 3031
             K Q + DS
Sbjct: 1007 TKSQAVADS 1015



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 10/136 (7%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            PV PP I    +++   EG  A+FQ ++SG    +V+W+   +++  S    +    +  
Sbjct: 897  PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 955

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-------SPTESYVQDQRSQYITDT 374
             L +      D G YT +A N  G + ++  L++E       S  +   +  +SQ + D+
Sbjct: 956  QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRESTKSQAVADS 1015

Query: 375  QQRETEERIEISEKAL 390
                T+E  +IS+K +
Sbjct: 1016 S--FTKEESKISQKEI 1029



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 64/285 (22%), Positives = 117/285 (41%), Gaps = 47/285 (16%)

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            ++T    +  PP+       + +     A F C +I       ++ W+   + L TG + 
Sbjct: 784  SVTLYVNAPEPPQVLQELQPVTVQSGKPARF-CAVISGRPQP-KISWYKEEQLLSTGFKC 841

Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
            K ++D     L +   +  DA +YTC+A N +G AT S  L V+  + +  + ++P +  
Sbjct: 842  KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVY-- 899

Query: 3667 SGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT 3726
                 I  L++T      +T E +   P RF                   CR   V    
Sbjct: 900  -PPAIITPLQDT------VTSEGQ---PARF------------------QCR---VSGTD 928

Query: 3727 MRIDWFHNGRPFATGSRVHTLNDF-GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +++ W+   +     SR   +  F     L+I   Y  D G YT  A+N  G  ++TA +
Sbjct: 929  LKVSWYSKDKKIKP-SRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 987

Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGR-ISDA--PKEEPIVS 3827
            +   +        L +  SG+ ++E  + + ++D+   KEE  +S
Sbjct: 988  SLEVQ-------ALDRQSSGKDVRESTKSQAVADSSFTKEESKIS 1025



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 22/61 (36%), Positives = 34/61 (55%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI WY   ++L  G + K   D    TL L++ +  D+ +YTC+A N  G A TS++
Sbjct: 822  PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 881

Query: 3001 V 3001
            +
Sbjct: 882  L 882



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           V   KI +KP++    E A   F+V +S +  P V WF     +  S+KH +++      
Sbjct: 348 VETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHK 406

Query: 323 LRVRNTQKSDSGHYT 337
           L ++N   SD+G YT
Sbjct: 407 LMLQNISPSDAGEYT 421



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 18/168 (10%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            KD+  +    +A +E S+      ++ ++WF+    I+ S + R V    +  L +    
Sbjct: 358  KDVTALENATVA-FEVSV---SHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNIS 413

Query: 3115 TTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174
             +D+G Y+       GQ      LEC  K   +    T  ++NIE + + ++A FEC V 
Sbjct: 414  PSDAGEYTAVV----GQ------LECKAKLFVETLHITKTMKNIE-VPETKTASFECEVS 462

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
              + P M   W  NG  +  S + K V       L I  T   DS EY
Sbjct: 463  HFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEY 507



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 625 IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
           + P +E  VYPP   I PL+     EG    F+ R   V    +K+ W    + I+  SR
Sbjct: 890 VSPDQEMPVYPPA-IITPLQDTVTSEGQPARFQCR---VSGTDLKVSWYSKDKKIK-PSR 944

Query: 685 FTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTS 738
           F  + +F     L++     +D G YT  A +A G   + A L +  +A   ++S
Sbjct: 945 FFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSS 999



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYIS-LDMLSLNIQDSGEYTCRAVSATGVAETKA 724
            P ++ +W K G+ I  S +  SI    YIS L++L   + D GEYTC+A +  G     A
Sbjct: 1231 PNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 1289

Query: 725  VLHVT 729
             L VT
Sbjct: 1290 TLTVT 1294



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 42/175 (24%), Positives = 69/175 (39%), Gaps = 13/175 (7%)

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           + +K  +D    E     F+  V+    P V WF  + +I+    H+ LV+E   H LM+
Sbjct: 352 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHR-LVSERKVHKLML 409

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
            N++ SD+G  T V     G+   +C+  +     V      +    + V E +      
Sbjct: 410 QNISPSDAGEYTAVV----GQ--LECKAKLF----VETLHITKTMKNIEVPETKTASFEC 459

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
                  P + W K+GV I  + + +I   G    L I      D+A Y     N
Sbjct: 460 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 513



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 2/89 (2%)

Query: 2779 HLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHT 2838
            HL ++  K GD   F C ++   D  + + W      +    R K + + +   L I + 
Sbjct: 1096 HLQDVTVKCGDTAQFLCVLKD--DSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNV 1153

Query: 2839 YEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
               D G+Y+C   N  G  TTS  L   G
Sbjct: 1154 QLVDQGLYSCIVHNDCGERTTSAVLSVEG 1182



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 10/96 (10%)

Query: 771 QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS- 829
           +F + ++D+  L++ R A FE +   VS+P + V+W KD + +  + RI  I    YV  
Sbjct: 615 EFRKHIKDIKVLEKKR-AMFECE---VSEPDITVQWMKDDQELQITDRI-KIQKEKYVHR 669

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           L I   R  DAG YTV A    G  +STA + V  R
Sbjct: 670 LLIPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 701



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 46/180 (25%), Positives = 69/180 (38%), Gaps = 16/180 (8%)

Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
           K  ++ +V E K   F+C V+    P + W  N  +I      KI+V +   H L+I N 
Sbjct: 442 KTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVV-QGKLHQLIIMNT 499

Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARA 514
           +  DS            E  F C  + +     V P  +      +N  E + +      
Sbjct: 500 STEDSA-----------EYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEV-T 547

Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
           V        W K+GV I    + ++ T     +L+I      DAA Y   A   A STAT
Sbjct: 548 VNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVA-GKATSTAT 606



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/198 (20%), Positives = 78/198 (39%), Gaps = 21/198 (10%)

Query: 2537 DPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXX 2596
            D  +   W   G +++   R + + +     L I +V   D GLY C   N  G      
Sbjct: 1117 DSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSA 1176

Query: 2597 XXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVE 2656
                     ++     PES          +++  E  ++  ++ AP+    ++  +  + 
Sbjct: 1177 ---------VLSVEGAPES---------ILHERIEQEIEMEMKAAPVIKRKIEPLEVAL- 1217

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G       +++  + PN++ +WFK G  +    +        + +L I   +  D G YT
Sbjct: 1218 GHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 1275

Query: 2717 CKATNLLGEAVSTASIKI 2734
            CKA+N  G    TA++ +
Sbjct: 1276 CKASNEYGSVSCTATLTV 1293



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 64/331 (19%), Positives = 127/331 (38%), Gaps = 35/331 (10%)

Query: 79  KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
           K+    +     FE  +  +  PV  W  K   +   +K+ +    +     L+++ I P
Sbjct: 358 KDVTALENATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVSERKVH--KLMLQNISP 414

Query: 139 GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
            D GEYT       G+  C   +  E                   + +E     T  +  
Sbjct: 415 SDAGEYTAVV----GQLECKAKLFVE-----------TLHITKTMKNIEVPETKTASFEC 459

Query: 199 EQSR-QTQKVAYTNGTDHSSTDDFKV---DTFEYRLLREVSFRESITKRYVGESDVQIST 254
           E S      +   NG +   ++ FK+         ++   S  +S    +V  +D Q+S 
Sbjct: 460 EVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND-QVSA 518

Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            +      V+P  I    ++   +E     F+V ++        W KNG  + +++K ++
Sbjct: 519 TLT-----VTPIMITSMLKDINAEEKDTITFEVTVNYEGIS-YKWLKNGVEIKSTDKCQM 572

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            T     +L +RN    D+  YT +A    G   ++  L VE+    + +  +   + + 
Sbjct: 573 RTKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLYVEARHIEFRKHIKDIKVLEK 628

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTE 405
           ++   E   E+SE  +  Q++K  Q+  +T+
Sbjct: 629 KRAMFE--CEVSEPDITVQWMKDDQELQITD 657



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
           +K++   E     FE  +     P+M   WLKNG  IE S +F  + +     L +++ +
Sbjct: 444 MKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 500

Query: 703 IQDSGEYTCRAVSATGVAETKAVLHVTP 730
            +DS EYT       G  +  A L VTP
Sbjct: 501 TEDSAEYT----FVCGNDQVSATLTVTP 524



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 7/89 (7%)

Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIAS 1107
            PLK  N ++EG  A  E +V    D+T +V+WY N +QI   +R+Q         L I  
Sbjct: 6    PLKDVN-VIEGTKAVLECKVSVP-DVT-SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINR 62

Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
              A D G Y ++     G  + + +++VE
Sbjct: 63   THASDEGPYKLI----VGRVETNCNLSVE 87



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/179 (22%), Positives = 67/179 (37%), Gaps = 13/179 (7%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
           +D +V EG     +C+V+      V W++ND QI+ D   + +V +     L+I     S
Sbjct: 8   KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV-KGTKQRLVINRTHAS 66

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           D G    +     G     C L+V   E++   K +     L   E + VV       + 
Sbjct: 67  DEGPYKLIV----GRVETNCNLSV---EKI---KIIRGLRDLTCTETQNVVFEVELSHSG 116

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA-QNVAGSTATRA 576
              + W      I P+ + +I   G    L +      D   Y   A +N+     T A
Sbjct: 117 ID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVA 174



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 53/217 (24%), Positives = 93/217 (42%), Gaps = 24/217 (11%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P+    L+  T V  G TA F C ++   D  + + + H G  ++ + R   + +     
Sbjct: 1091 PKIFLHLQDVT-VKCGDTAQFLCVLKD--DSFIDVTWTHEGAKIEESERLKQSQNGNIQF 1147

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L I +    D G YS    N  G  T++  ++V  +G+   ES   E +E+  E+E    
Sbjct: 1148 LTICNVQLVDQGLYSCIVHNDCGERTTSAVLSV--EGA--PESILHERIEQEIEMEMKAA 1203

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
                    PV +++    +PL+    +  G  A F C +     P ++ +WF+  + I +
Sbjct: 1204 --------PVIKRK---IEPLE----VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYE 1246

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            S + +        S+ I   +  D G Y C+ASN  G
Sbjct: 1247 SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYG 1283



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/92 (28%), Positives = 42/92 (45%)

Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
           +GE   +++T    +   V   KI +  +N  + E  DA F V+L+      V W KNG 
Sbjct: 242 IGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV 301

Query: 305 RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            L ++ K+ I       +LR++N    D   Y
Sbjct: 302 VLESNEKYAISVKGTIYSLRIKNCAIVDESVY 333



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KDI+V E + A FE     V +P + V+W+++   ++ ++R+    +     L +
Sbjct: 616  FRKHIKDIKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLI 672

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                  D+G YT  A    G  V+++ LFV+ +
Sbjct: 673  PSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 701



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 19/163 (11%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSG 3119
            +E Q   +E  L  +G   + + W +  K I+ S + + + A G +  L +L     D G
Sbjct: 101  TETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYK-IEAHGKIYKLTVLNMMKDDEG 156

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             Y+  A       +++V    + K    +            + + Q A FEC V    +P
Sbjct: 157  KYTFYAGENITSGKLTVAGGAISKPLTDQT-----------VAESQEAVFECEVA---NP 202

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            D K EW  +G+ +  +  I++ SD     L IA T+  D GEY
Sbjct: 203  DSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY 245



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 8/94 (8%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            F  H+K   K++E +    E +V   ++P++ ++W K+   L    R+K   +  +  L 
Sbjct: 616  FRKHIKDI-KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLL 671

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            I S R  D+G YT  A    G  VSTA + +E R
Sbjct: 672  IPSTRMSDAGKYTVVA----GGNVSTAKLFVEGR 701



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            K++E + A FE  V   S+  +TV+W  + +++   +RI+   +     L I S R  D+
Sbjct: 624  KVLEKKRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 680

Query: 1114 GVYTVVARNAAGEAQL 1129
            G YTVVA      A+L
Sbjct: 681  GKYTVVAGGNVSTAKL 696



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 16/179 (8%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  P   T++ KDI +  E     +E ++   G   +  +W  NG  I+++ + +     
Sbjct: 521  TVTPIMITSMLKDI-NAEEKDTITFEVTVNYEG---ISYKWLKNGVEIKSTDKCQMRTKK 576

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L I      D+  Y+  A      A + V+   ++        F  HI++I+ L+ 
Sbjct: 577  LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIE--------FRKHIKDIKVLEK 628

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             + A FEC V    +PD+ ++W  + Q ++ + RIK   +     L I  T+  D+G+Y
Sbjct: 629  -KRAMFECEV---SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKY 683



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/69 (24%), Positives = 37/69 (53%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E ++ P+++ +W+  G+ + +  +  + S     +L+++     D G YTCKA N+ G  
Sbjct: 1226 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 1285

Query: 2996 FTSSTVYCT 3004
              ++T+  T
Sbjct: 1286 SCTATLTVT 1294



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 8/102 (7%)

Query: 1688 LNQL-EDTSKYQRHSAQD----EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL 1742
            LN + +D  KY  ++ ++    ++       + P+ D  VAE+Q A FE     V +P  
Sbjct: 148  LNMMKDDEGKYTFYAGENITSGKLTVAGGAISKPLTDQTVAESQEAVFECE---VANPDS 204

Query: 1743 RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYT 1784
            + EWLR+G  +  +N + +  D     L +     +D G YT
Sbjct: 205  KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYT 246



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           +F K  +D  V E K   F+C V+  P   V W  +D++++     KI   E   H L+I
Sbjct: 615 EFRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQ-KEKYVHRLLI 672

Query: 453 TNVTLSDSGVVTCVA-RNKSGETAF----QCRLNVIEKEQVVAPK 492
            +  +SD+G  T VA  N S    F      R+  I+KE  V  K
Sbjct: 673 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEK 717



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I  L ++ C E  N+ FE  +  S    + + W F +K +   ++YK         L + 
Sbjct: 92   IRGLRDLTCTETQNVVFEVELSHSG---IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVL 148

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            +  ++D G YT  A    G   TSG L   G
Sbjct: 149  NMMKDDEGKYTFYA----GENITSGKLTVAG 175



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            +   TV ES+   FEC V    +P  + EW R+GK LP  +  R+  D     L I    
Sbjct: 182  LTDQTVAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATK 238

Query: 3896 AEDSGEY 3902
             +D GEY
Sbjct: 239  LDDIGEY 245



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            ++E Q A +EC +    +P+ + EW  +GK L   +  R+ +D     L I     +D G
Sbjct: 187  VAESQEAVFECEVA---NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIG 243

Query: 1916 EYTCKAINNLGQA---VSSIRLNVQSKESIIRDSQ 1947
            EYT K   +   A   V ++++    K   + ++Q
Sbjct: 244  EYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQ 278



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 910 EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
           EF+  IKD I + E   A FE     + +  + V+W+KD + ++ + RI          L
Sbjct: 615 EFRKHIKD-IKVLEKKRAMFECE---VSEPDITVQWMKDDQELQITDRIKIQKEKYVHRL 670

Query: 970 TIKSVTVHDAGHYTCRAYNAIGQA 993
            I S  + DAG YT  A   +  A
Sbjct: 671 LIPSTRMSDAGKYTVVAGGNVSTA 694



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EGQ    + +V   TD  LK+ W+     +      + T       L I     +D G Y
Sbjct: 914  EGQPARFQCRVSG-TD--LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 970

Query: 2716 TCKATNLLGEAVSTASIKIE 2735
            T  A+N +G+  STA++ +E
Sbjct: 971  TFVASNAVGQVSSTANLSLE 990



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 774 RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIM 833
           +PL D   + E + A FE +   V++P  + EW +DG+ +  ++ I S  +     L I 
Sbjct: 180 KPLTDQ-TVAESQEAVFECE---VANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIA 235

Query: 834 HLRAEDAGSYTVR-AVNKLGEAISTASIRV 862
             + +D G YT + A +K    +   ++++
Sbjct: 236 ATKLDDIGEYTYKVATSKTSAKLKVEAVKI 265



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 2245 VTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDI 2304
            +T+      V E KTA FEC+V   + P++ ++   NG  ++ + +F I        L I
Sbjct: 440  ITKTMKNIEVPETKTASFECEVSHFNVPSMWLK---NGVEIEMSEKFKIVVQGKLHQLII 496

Query: 2305 QHCVPEDAGEYS 2316
             +   ED+ EY+
Sbjct: 497  MNTSTEDSAEYT 508


>BC005376-1|AAH05376.1|  498|Homo sapiens myotilin protein.
          Length = 498

 Score =  142 bits (344), Expect = 3e-32
 Identities = 70/207 (33%), Positives = 117/207 (56%), Gaps = 2/207 (0%)

Query: 374 TQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR 433
           T + +  ++  I EK   P+F++V ++  + EG+  R D +V+G P P+V+W++N R ++
Sbjct: 232 TSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ 291

Query: 434 DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
            D  HK++V+E G H+L+   V  SD+G   CVA+N++GE  F  +L+V+ KE   AP F
Sbjct: 292 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 351

Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDG-GASTLDIP 551
           + +  +  V EG+ V L  +    P P++ W+++   +  N + + ++ D  G  TL I 
Sbjct: 352 IYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK 411

Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578
                DA WY  +A N AG T    RL
Sbjct: 412 DVNKKDAGWYTVSAVNEAGVTTCNTRL 438



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 69/220 (31%), Positives = 103/220 (46%), Gaps = 17/220 (7%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTL 4571
            PP F    +N+++  G+  R+D KV+G    DV W  NG+ VQ  D+   I+ E G ++L
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
            +       D+G Y CVA N AGEA    +  V     K           AP  I +P + 
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHK----------RAPMFIYKP-QS 357

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK--PSKYFQMSRTADEYTLRISEAFPED 4689
            K V EG +++  C+I   P P + W + +++++    +           TL I +   +D
Sbjct: 358  KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 417

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVT-QPDQADNLPALTPLR 4728
             G Y   A N AG  T   +L VT +P+Q   LPA   LR
Sbjct: 418  AGWYTVSAVNEAGVTTCNTRLDVTARPNQ--TLPAPKQLR 455



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 58/210 (27%), Positives = 92/210 (43%), Gaps = 10/210 (4%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-- 4467
            PP F +  +   + E    R + +  G P P + WY     ++ S D      S K +  
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGLHS 307

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI   V   D+  +A VA+NR G A  +  L V  K  +       P F    Q+  V  
Sbjct: 308  LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR-----APMFIYKPQSKKVLE 362

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYE 4585
            G  V+L+ +++   P  ++W +N + VQ +     L +D  G  TLLI +   +D+G Y 
Sbjct: 363  GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 422

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
              A+N AG   C+    V+    +  P P+
Sbjct: 423  VSAVNEAGVTTCNTRLDVTARPNQTLPAPK 452



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 53/190 (27%), Positives = 93/190 (48%), Gaps = 13/190 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAH--YEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF- 3103
            PP F  V +++  I EG+     ++ S +P  D    + W+ NG+T+++    + + +  
Sbjct: 249  PPRFIQVPENM-SIDEGRFCRMDFKVSGLPAPD----VSWYLNGRTVQSDDLHKMIVSEK 303

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G+  L     + +D+G Y+C A N+ G+A  +V+L+ + K   + P F    Q+ + L +
Sbjct: 304  GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL-E 362

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST-RIKTVSD-FGFVVLDIAYTQNHDSGE 3221
            G S   EC +  +  P  K+ W  N + ++ +T RI    D  G V L I      D+G 
Sbjct: 363  GDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGW 420

Query: 3222 YVCRAYNKYG 3231
            Y   A N+ G
Sbjct: 421  YTVSAVNEAG 430



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 48/195 (24%), Positives = 81/195 (41%), Gaps = 3/195 (1%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP  I+  ++  + EG+      K+ G P P V WY   + ++     +M  +       
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 4682 ISEAF-PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I E     D G Y CVA N AG  T   +L V   +       +   +   V EG   + 
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGN--NAVLLIGNTYEEDTGTFTCRATTA 4798
            + QI++   P + W R   ++    D   +++ N     LLI +  ++D G +T  A   
Sbjct: 369  ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 428

Query: 4799 AGQVETSAKLVVKSK 4813
            AG    + +L V ++
Sbjct: 429  AGVTTCNTRLDVTAR 443



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 77/290 (26%), Positives = 122/290 (42%), Gaps = 50/290 (17%)

Query: 1791 LGEAVTSSTLFVQSKASLQLESQHESALQKIQ--QLEDSSRYQRREDV--EVAVNQA--- 1843
            LG    ++    Q  +  Q   QH S   ++Q    +  SR   R DV  + A+ +    
Sbjct: 190  LGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYP 249

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS-NDFGFA 1902
            PRFI Q+     + EG+    + ++   P P+  V WY NG+ +QS   ++   ++ G  
Sbjct: 250  PRFI-QVPENMSIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLH 306

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
            +L    V   D+G Y C A N  G+A  +++L+V +KE                      
Sbjct: 307  SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE---------------------- 344

Query: 1963 RYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ 2022
             +KRA       + KPQ      + +V EG  V LE  ++ +  P  ++ W  N   VQ 
Sbjct: 345  -HKRA----PMFIYKPQ------SKKVLEGDSVKLECQISAI--PPPKLFWKRNNEMVQF 391

Query: 2023 GHRFKTTY--DFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
                 + Y  + G V L I     +D G Y   A N  G  VTT + ++D
Sbjct: 392  NTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG--VTTCNTRLD 439



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 54/230 (23%), Positives = 98/230 (42%), Gaps = 32/230 (13%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TL 323
           PP+  Q P N  + EG   +   ++SG P P V+W+ NG+ + + + H++I +     +L
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                + SD+G Y  +A+N  G         V+    +    +   +I   Q        
Sbjct: 309 IFEVVRASDAGAYACVAKNRAG----EATFTVQLDVLAKEHKRAPMFIYKPQ-------- 356

Query: 384 EISEKALAPQFVKV-CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH-KIL 441
             S+K L    VK+ CQ               ++  P P++ W  N+  ++ + +   + 
Sbjct: 357 --SKKVLEGDSVKLECQ---------------ISAIPPPKLFWKRNNEMVQFNTDRISLY 399

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
            + +G   L+I +V   D+G  T  A N++G T    RL+V  +     P
Sbjct: 400 QDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 449



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 6/103 (5%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL-- 3747
            EK  PPRF +++ +N+ + EG     D +V   G P   + W+ NGR   +   +H +  
Sbjct: 245  EKFYPPRF-IQVPENMSIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDD-LHKMIV 300

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            ++ G  +L  + + A DAG Y C A N+ G AT T ++   AK
Sbjct: 301  SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 343



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL--TYDGMYHF 4167
            PP F+ +P+ ++++EG + R   +V+G P P V W LNG T+ +   +K+  +  G++  
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
                 R  D G    +             L V+ +
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 343



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 6/139 (4%)

Query: 1938 SKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK---PQFGKPIKNAEVTEGHP 1994
            +++S   +S+H         +   S  +  V D   + EK   P+F +  +N  + EG  
Sbjct: 207  AQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRF 266

Query: 1995 VHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCK 2053
              ++  ++ +  P   V WY NGR VQ     K    + G  +L      A D G Y C 
Sbjct: 267  CRMDFKVSGL--PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACV 324

Query: 2054 ATNAVGEAVTTSSVKVDAK 2072
            A N  GEA  T  + V AK
Sbjct: 325  AKNRAGEATFTVQLDVLAK 343



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 1/91 (1%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F Q+ +N    +G   + + K+ G P P VSW      +   + + M  +E+ G  S
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEK-GLHS 307

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L+ + +   D G Y C A+N+ GEA  +V +
Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQL 338



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 37/127 (29%), Positives = 66/127 (51%), Gaps = 7/127 (5%)

Query: 759 QESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
           Q++I+E+    P+FI+  +++  + EGR    + +++ +  P   V WY +GR + +   
Sbjct: 240 QDAIQEKFYP-PRFIQVPENMS-IDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDL 295

Query: 819 ITSIFNF-GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI--P 875
              I +  G  SL    +RA DAG+Y   A N+ GEA  T  + V A+    A + I  P
Sbjct: 296 HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP 355

Query: 876 EQRRYIE 882
           + ++ +E
Sbjct: 356 QSKKVLE 362



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/104 (29%), Positives = 54/104 (51%), Gaps = 4/104 (3%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS-NRLTTMHD-FG 1766
            +AP+F    +  +V E  +   E ++  +  PKL   W RN   ++ + +R++   D  G
Sbjct: 347  RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTG 404

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             V L +K VN +D+G YT  A+NE G    ++ L V ++ +  L
Sbjct: 405  RVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTL 448



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 12/134 (8%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG-HR 1492
            D++ +     P F+ +P+S + V+EG  V  EC++  +     K+ W +N + V     R
Sbjct: 339  DVLAKEHKRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDR 395

Query: 1493 FRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEA 1550
                 D  G V L I D+  +D+G YT  AVN  G        TC +  D+  R  Q   
Sbjct: 396  ISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGV------TTCNTRLDVTARPNQTLP 449

Query: 1551 GLEQIQVLEDRSKY 1564
              +Q++V    SKY
Sbjct: 450  APKQLRVRPTFSKY 463



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 4/97 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--FGYI 694
           P FI   +S   +EG  +  E +I  +  P  K+ W +N + ++ ++   S+++   G +
Sbjct: 349 PMFIYKPQSKKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNTGRV 406

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
           +L +  +N +D+G YT  AV+  GV      L VT R
Sbjct: 407 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 2/88 (2%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGDVS 130
           P+F    ++ +  +G + K E ++   P P + W R    +V+ N   +  Y + TG V+
Sbjct: 349 PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNE-MVQFNTDRISLYQDNTGRVT 407

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS 158
           LLIK +   D G YT +A N+ G   C+
Sbjct: 408 LLIKDVNKKDAGWYTVSAVNEAGVTTCN 435



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 7/114 (6%)

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPL 3600
            G V+      E   PP F   P ++ + E      + ++  +P  D    V W+ NG+ +
Sbjct: 235  GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPD----VSWYLNGRTV 290

Query: 3601 LTGSRVKTI-NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
             +    K I ++ G   L    V   DAG Y C A NR GEAT + +L V  ++
Sbjct: 291  QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 344



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 7/120 (5%)

Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           + ++  + P FI   Q    L EG +   E Q++ +  P  ++ W ++   +  ++   S
Sbjct: 341 LAKEHKRAPMFIYKPQSKKVL-EGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRIS 397

Query: 822 IF--NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRR 879
           ++  N G V+L I  +  +DAG YTV AVN+ G       + V AR   T  L  P+Q R
Sbjct: 398 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQT--LPAPKQLR 455



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY-DMGFV 3887
            PP+FI   ++ +++E    R + +V     P   + WY NG+ + S   ++ +  + G  
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLH 306

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGE 3912
            SL    V A D+G Y C A N  GE
Sbjct: 307  SLIFEVVRASDAGAYACVAKNRAGE 331



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 5/123 (4%)

Query: 2874 DTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEG 2933
            +++H + +     V     +R     + ++ +  YP P +I  +     + EG+   ++ 
Sbjct: 214  NSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYP-PRFI-QVPENMSIDEGRFCRMDF 271

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKL-TSDFGFVTLDLVDVYERDSGIYTCKAYNKR 2992
            +V     PD  + WY NG+ ++     K+  S+ G  +L    V   D+G Y C A N+ 
Sbjct: 272  KVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRA 329

Query: 2993 GEA 2995
            GEA
Sbjct: 330  GEA 332



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 8/96 (8%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSAN-RIQTYHDFG 1099
            PRF+  +     I EG+    + +V   P  D    V WY NG+ + S +       + G
Sbjct: 250  PRFI-QVPENMSIDEGRFCRMDFKVSGLPAPD----VSWYLNGRTVQSDDLHKMIVSEKG 304

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              +L    VRA D+G Y  VA+N AGEA  +  + V
Sbjct: 305  LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 340



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ-SGHRYRTSND-F 1899
            +AP FI +     K+ EG S   EC+I   P P  ++ W  N +++Q +  R     D  
Sbjct: 347  RAPMFIYKPQSK-KVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNT 403

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            G   L I  V  +D+G YT  A+N  G    + RL+V ++
Sbjct: 404  GRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 2/100 (2%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSI 4467
            + P+F  K Q  +V E +  + E +    P P + W R N  ++ N+    ++  +T  +
Sbjct: 347  RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 406

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
             L+I+ V  +D+  +   A N  G   C+  L V  +  Q
Sbjct: 407  TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQ 446



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 4/105 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E    P F   + + +SI EG F   + ++   G     V W  +GR V++       
Sbjct: 243  IQEKFYPPRF-IQVPENMSIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMI 299

Query: 962  FNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
             +  G  +L  + V   DAG Y C A N  G+AT +  L ++ K+
Sbjct: 300  VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 344



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 10/157 (6%)

Query: 1258 LGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA------- 1310
            LG  + +A+ +  + S      Q+     ++Q+     R     R D+    A       
Sbjct: 190  LGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYP 249

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY-EFDYVA 1369
            P+F +   N+   EG    ++ ++   G     V W+ NG+ +++    +    E    +
Sbjct: 250  PRFIQVPENMSIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 307

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
            L    V   D+G Y C A N+ GEA  +  L V+AK+
Sbjct: 308  LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 344



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 7/104 (6%)

Query: 1159 ESKFVEPMYQIEEISKSKPVFV-QPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
            E+ F   +  + +  K  P+F+ +P S    V EG ++ LEC++  +  P  ++ W  N 
Sbjct: 331  EATFTVQLDVLAKEHKRAPMFIYKPQSKK--VLEGDSVKLECQISAIPPP--KLFWKRNN 386

Query: 1218 RSVTVGS-RFKTYYD-FGFVALDIIHATSADTGEYTVRAVNHLG 1259
              V   + R   Y D  G V L I      D G YTV AVN  G
Sbjct: 387  EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 430



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY--DMGFV 3887
            P FI + +S  V E + V+ EC++     PKL   W RN +++       ++Y  + G V
Sbjct: 349  PMFIYKPQSKKVLEGDSVKLECQISAIPPPKL--FWKRNNEMVQFNTDRISLYQDNTGRV 406

Query: 3888 SLDILYVYAEDSGEYICRAVNDFG 3911
            +L I  V  +D+G Y   AVN+ G
Sbjct: 407  TLLIKDVNKKDAGWYTVSAVNEAG 430



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 9/124 (7%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF-HDFGI 3339
            PP+FI Q+ +   + EG+    + ++  +  PD  V W+ NG+ +     ++    + G+
Sbjct: 249  PPRFI-QVPENMSIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGL 305

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN-----LILDSQLPRGMEGGL 3394
              L        ++G Y CVA N+ G  +    L   +KE+      I   Q  + +EG  
Sbjct: 306  HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS 365

Query: 3395 EKLQ 3398
             KL+
Sbjct: 366  VKLE 369



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 10/127 (7%)

Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-THDFGYVALDILYTYAED 2178
            ++ EG     + +V  +  P   + W+ NG+ +++   ++    + G  +L      A D
Sbjct: 260  SIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 317

Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAG--HRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEE 2236
            +G Y C A N+ GEA  T  L V    H+   +    P   +K+     +G S ++E + 
Sbjct: 318  AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQS-KKV----LEGDSVKLECQI 372

Query: 2237 PKISPPR 2243
              I PP+
Sbjct: 373  SAIPPPK 379



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 9/133 (6%)

Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468
            D    +EK   P F     N+ ++ EG     + +++    P+  V WY NG+++++   
Sbjct: 239  DQDAIQEKFYPPRFIQVPENM-SIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDL 295

Query: 3469 FRTFC-DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN-----IILES 3522
             +    + G   L        D+G Y C A N  GEA  T  + V  K +      I + 
Sbjct: 296  HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP 355

Query: 3523 QLPKGMEGTIDKI 3535
            Q  K +EG   K+
Sbjct: 356  QSKKVLEGDSVKL 368



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS-RFKLTSD-FGFVTLDLVDVYER 2979
            +++EG  + LE Q+     P  K+ W  N ++++  + R  L  D  G VTL + DV ++
Sbjct: 359  KVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKK 416

Query: 2980 DSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            D+G YT  A N+ G    ++ +  T++ N
Sbjct: 417  DAGWYTVSAVNEAGVTTCNTRLDVTARPN 445



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ-SAARFHITFD-FGYVSLDIQHCVPED 2311
            V EG +   ECQ+  +  P L   +  N + +Q +  R  +  D  G V+L I+    +D
Sbjct: 360  VLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 417

Query: 2312 AGEYSVKAINALGHCTSAISMTVTAK 2337
            AG Y+V A+N  G  T    + VTA+
Sbjct: 418  AGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL-LTGSRVKTIND 3611
            E    P F   P    + E  S   EC++  +     ++ W  N + +     R+    D
Sbjct: 344  EHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQD 401

Query: 3612 -FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
              G V L I  V ++DAG YT  A N  G  T + +L V  R
Sbjct: 402  NTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF--D 2696
            ++AP+F    +S  K++EG  V LE Q+     P  K+ W +N   +       S +  +
Sbjct: 346  KRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDN 402

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             G VTL I  +   D+G YT  A N  G  V+T + +++
Sbjct: 403  TGRVTLLIKDVNKKDAGWYTVSAVNEAG--VTTCNTRLD 439



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 4/88 (4%)

Query: 2504 EFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THD 2562
            +F  P F QV    S + EG+    + +V   G P+    WY+NG  ++     +    +
Sbjct: 246  KFYPPRFIQVPENMS-IDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMIVSE 302

Query: 2563 FGFVTLDINSVVANDAGLYMCKAINRAG 2590
             G  +L    V A+DAG Y C A NRAG
Sbjct: 303  KGLHSLIFEVVRASDAGAYACVAKNRAG 330



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHD-FGYVALDIASVR 1109
            + K++EG S   E ++       +   W  N + +  + +RI  Y D  G V L I  V 
Sbjct: 357  SKKVLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVN 414

Query: 1110 AEDSGVYTVVARNAAGEAQLSASMTVETR 1138
             +D+G YTV A N AG    +  + V  R
Sbjct: 415  KKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVSLDITHTYEEDSG 2844
            EGD++  EC +  S  P  K+ W  NN+ +   T   S +  +   V+L I    ++D+G
Sbjct: 362  EGDSVKLECQI--SAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 419

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKN 2870
             YT  A N  G  T +  L  T   N
Sbjct: 420  WYTVSAVNEAGVTTCNTRLDVTARPN 445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 4084 IEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVM 4143
            + K R  EA++ V  + + +E K    P+F+  P +  V EG+  +  C+++  P P++ 
Sbjct: 324  VAKNRAGEATFTVQLDVLAKEHKRA--PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLF 381

Query: 4144 WLLNGNTI-VNGSRYKLTYD 4162
            W  N   +  N  R  L  D
Sbjct: 382  WKRNNEMVQFNTDRISLYQD 401



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT-V 3201
            + K   PRF    +N+  + +G+    +  V  +  PD  + WY NG+ ++     K  V
Sbjct: 244  QEKFYPPRFIQVPENMS-IDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIV 300

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            S+ G   L     +  D+G Y C A N+ GE
Sbjct: 301  SEKGLHSLIFEVVRASDAGAYACVAKNRAGE 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-DSSRITKTHDFGYV 2434
            P F Q  +N+ +I EG+    D ++   G P   V W+ N + ++ D        + G  
Sbjct: 250  PRFIQVPENM-SIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH 306

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
            S+    VR  D G Y C A N  GE
Sbjct: 307  SLIFEVVRASDAGAYACVAKNRAGE 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-DFGLVTLSINSLRNDDSGI 2714
            EG+   ++ +V     P+  + W+ NG T+ +    K    + GL +L    +R  D+G 
Sbjct: 263  EGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGA 320

Query: 2715 YTCKATNLLGEAVSTASIKI 2734
            Y C A N  GEA  T  + +
Sbjct: 321  YACVAKNRAGEATFTVQLDV 340



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFF-NFGYVALTIKSVTVHD 978
            + EG     E ++  I    L   W ++   V+ ++ RI+ +  N G V L IK V   D
Sbjct: 360  VLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 417

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTK 1004
            AG YT  A N  G  T +  L +  +
Sbjct: 418  AGWYTVSAVNEAGVTTCNTRLDVTAR 443


>AF144477-1|AAD44754.1|  498|Homo sapiens myotilin protein.
          Length = 498

 Score =  142 bits (344), Expect = 3e-32
 Identities = 70/207 (33%), Positives = 117/207 (56%), Gaps = 2/207 (0%)

Query: 374 TQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR 433
           T + +  ++  I EK   P+F++V ++  + EG+  R D +V+G P P+V+W++N R ++
Sbjct: 232 TSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ 291

Query: 434 DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
            D  HK++V+E G H+L+   V  SD+G   CVA+N++GE  F  +L+V+ KE   AP F
Sbjct: 292 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 351

Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDG-GASTLDIP 551
           + +  +  V EG+ V L  +    P P++ W+++   +  N + + ++ D  G  TL I 
Sbjct: 352 IYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK 411

Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578
                DA WY  +A N AG T    RL
Sbjct: 412 DVNKKDAGWYTVSAVNEAGVTTCNTRL 438



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 69/220 (31%), Positives = 103/220 (46%), Gaps = 17/220 (7%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTL 4571
            PP F    +N+++  G+  R+D KV+G    DV W  NG+ VQ  D+   I+ E G ++L
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
            +       D+G Y CVA N AGEA    +  V     K           AP  I +P + 
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHK----------RAPMFIYKP-QS 357

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK--PSKYFQMSRTADEYTLRISEAFPED 4689
            K V EG +++  C+I   P P + W + +++++    +           TL I +   +D
Sbjct: 358  KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 417

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVT-QPDQADNLPALTPLR 4728
             G Y   A N AG  T   +L VT +P+Q   LPA   LR
Sbjct: 418  AGWYTVSAVNEAGVTTCNTRLDVTARPNQ--TLPAPKQLR 455



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 58/210 (27%), Positives = 92/210 (43%), Gaps = 10/210 (4%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-- 4467
            PP F +  +   + E    R + +  G P P + WY     ++ S D      S K +  
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGLHS 307

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI   V   D+  +A VA+NR G A  +  L V  K  +       P F    Q+  V  
Sbjct: 308  LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR-----APMFIYKPQSKKVLE 362

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYE 4585
            G  V+L+ +++   P  ++W +N + VQ +     L +D  G  TLLI +   +D+G Y 
Sbjct: 363  GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 422

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
              A+N AG   C+    V+    +  P P+
Sbjct: 423  VSAVNEAGVTTCNTRLDVTARPNQTLPAPK 452



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 53/190 (27%), Positives = 93/190 (48%), Gaps = 13/190 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAH--YEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF- 3103
            PP F  V +++  I EG+     ++ S +P  D    + W+ NG+T+++    + + +  
Sbjct: 249  PPRFIQVPENM-SIDEGRFCRMDFKVSGLPAPD----VSWYLNGRTVQSDDLHKMIVSEK 303

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G+  L     + +D+G Y+C A N+ G+A  +V+L+ + K   + P F    Q+ + L +
Sbjct: 304  GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL-E 362

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST-RIKTVSD-FGFVVLDIAYTQNHDSGE 3221
            G S   EC +  +  P  K+ W  N + ++ +T RI    D  G V L I      D+G 
Sbjct: 363  GDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGW 420

Query: 3222 YVCRAYNKYG 3231
            Y   A N+ G
Sbjct: 421  YTVSAVNEAG 430



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 48/195 (24%), Positives = 81/195 (41%), Gaps = 3/195 (1%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP  I+  ++  + EG+      K+ G P P V WY   + ++     +M  +       
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 4682 ISEAF-PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I E     D G Y CVA N AG  T   +L V   +       +   +   V EG   + 
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGN--NAVLLIGNTYEEDTGTFTCRATTA 4798
            + QI++   P + W R   ++    D   +++ N     LLI +  ++D G +T  A   
Sbjct: 369  ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 428

Query: 4799 AGQVETSAKLVVKSK 4813
            AG    + +L V ++
Sbjct: 429  AGVTTCNTRLDVTAR 443



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 77/290 (26%), Positives = 122/290 (42%), Gaps = 50/290 (17%)

Query: 1791 LGEAVTSSTLFVQSKASLQLESQHESALQKIQ--QLEDSSRYQRREDV--EVAVNQA--- 1843
            LG    ++    Q  +  Q   QH S   ++Q    +  SR   R DV  + A+ +    
Sbjct: 190  LGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYP 249

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS-NDFGFA 1902
            PRFI Q+     + EG+    + ++   P P+  V WY NG+ +QS   ++   ++ G  
Sbjct: 250  PRFI-QVPENMSIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLH 306

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
            +L    V   D+G Y C A N  G+A  +++L+V +KE                      
Sbjct: 307  SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE---------------------- 344

Query: 1963 RYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ 2022
             +KRA       + KPQ      + +V EG  V LE  ++ +  P  ++ W  N   VQ 
Sbjct: 345  -HKRA----PMFIYKPQ------SKKVLEGDSVKLECQISAI--PPPKLFWKRNNEMVQF 391

Query: 2023 GHRFKTTY--DFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
                 + Y  + G V L I     +D G Y   A N  G  VTT + ++D
Sbjct: 392  NTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG--VTTCNTRLD 439



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 54/230 (23%), Positives = 98/230 (42%), Gaps = 32/230 (13%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TL 323
           PP+  Q P N  + EG   +   ++SG P P V+W+ NG+ + + + H++I +     +L
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                + SD+G Y  +A+N  G         V+    +    +   +I   Q        
Sbjct: 309 IFEVVRASDAGAYACVAKNRAG----EATFTVQLDVLAKEHKRAPMFIYKPQ-------- 356

Query: 384 EISEKALAPQFVKV-CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH-KIL 441
             S+K L    VK+ CQ               ++  P P++ W  N+  ++ + +   + 
Sbjct: 357 --SKKVLEGDSVKLECQ---------------ISAIPPPKLFWKRNNEMVQFNTDRISLY 399

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
            + +G   L+I +V   D+G  T  A N++G T    RL+V  +     P
Sbjct: 400 QDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 449



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 6/103 (5%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL-- 3747
            EK  PPRF +++ +N+ + EG     D +V   G P   + W+ NGR   +   +H +  
Sbjct: 245  EKFYPPRF-IQVPENMSIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDD-LHKMIV 300

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            ++ G  +L  + + A DAG Y C A N+ G AT T ++   AK
Sbjct: 301  SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 343



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL--TYDGMYHF 4167
            PP F+ +P+ ++++EG + R   +V+G P P V W LNG T+ +   +K+  +  G++  
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
                 R  D G    +             L V+ +
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 343



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 6/139 (4%)

Query: 1938 SKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK---PQFGKPIKNAEVTEGHP 1994
            +++S   +S+H         +   S  +  V D   + EK   P+F +  +N  + EG  
Sbjct: 207  AQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRF 266

Query: 1995 VHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCK 2053
              ++  ++ +  P   V WY NGR VQ     K    + G  +L      A D G Y C 
Sbjct: 267  CRMDFKVSGL--PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACV 324

Query: 2054 ATNAVGEAVTTSSVKVDAK 2072
            A N  GEA  T  + V AK
Sbjct: 325  AKNRAGEATFTVQLDVLAK 343



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 1/91 (1%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F Q+ +N    +G   + + K+ G P P VSW      +   + + M  +E+ G  S
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEK-GLHS 307

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L+ + +   D G Y C A+N+ GEA  +V +
Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQL 338



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 37/127 (29%), Positives = 66/127 (51%), Gaps = 7/127 (5%)

Query: 759 QESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
           Q++I+E+    P+FI+  +++  + EGR    + +++ +  P   V WY +GR + +   
Sbjct: 240 QDAIQEKFYP-PRFIQVPENMS-IDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDL 295

Query: 819 ITSIFNF-GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI--P 875
              I +  G  SL    +RA DAG+Y   A N+ GEA  T  + V A+    A + I  P
Sbjct: 296 HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP 355

Query: 876 EQRRYIE 882
           + ++ +E
Sbjct: 356 QSKKVLE 362



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/104 (29%), Positives = 54/104 (51%), Gaps = 4/104 (3%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS-NRLTTMHD-FG 1766
            +AP+F    +  +V E  +   E ++  +  PKL   W RN   ++ + +R++   D  G
Sbjct: 347  RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTG 404

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             V L +K VN +D+G YT  A+NE G    ++ L V ++ +  L
Sbjct: 405  RVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTL 448



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 12/134 (8%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG-HR 1492
            D++ +     P F+ +P+S + V+EG  V  EC++  +     K+ W +N + V     R
Sbjct: 339  DVLAKEHKRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDR 395

Query: 1493 FRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEA 1550
                 D  G V L I D+  +D+G YT  AVN  G        TC +  D+  R  Q   
Sbjct: 396  ISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGV------TTCNTRLDVTARPNQTLP 449

Query: 1551 GLEQIQVLEDRSKY 1564
              +Q++V    SKY
Sbjct: 450  APKQLRVRPTFSKY 463



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 4/97 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--FGYI 694
           P FI   +S   +EG  +  E +I  +  P  K+ W +N + ++ ++   S+++   G +
Sbjct: 349 PMFIYKPQSKKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNTGRV 406

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
           +L +  +N +D+G YT  AV+  GV      L VT R
Sbjct: 407 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 2/88 (2%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGDVS 130
           P+F    ++ +  +G + K E ++   P P + W R    +V+ N   +  Y + TG V+
Sbjct: 349 PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNE-MVQFNTDRISLYQDNTGRVT 407

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS 158
           LLIK +   D G YT +A N+ G   C+
Sbjct: 408 LLIKDVNKKDAGWYTVSAVNEAGVTTCN 435



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 7/114 (6%)

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPL 3600
            G V+      E   PP F   P ++ + E      + ++  +P  D    V W+ NG+ +
Sbjct: 235  GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPD----VSWYLNGRTV 290

Query: 3601 LTGSRVKTI-NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
             +    K I ++ G   L    V   DAG Y C A NR GEAT + +L V  ++
Sbjct: 291  QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 344



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 7/120 (5%)

Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           + ++  + P FI   Q    L EG +   E Q++ +  P  ++ W ++   +  ++   S
Sbjct: 341 LAKEHKRAPMFIYKPQSKKVL-EGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRIS 397

Query: 822 IF--NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRR 879
           ++  N G V+L I  +  +DAG YTV AVN+ G       + V AR   T  L  P+Q R
Sbjct: 398 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQT--LPAPKQLR 455



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY-DMGFV 3887
            PP+FI   ++ +++E    R + +V     P   + WY NG+ + S   ++ +  + G  
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLH 306

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGE 3912
            SL    V A D+G Y C A N  GE
Sbjct: 307  SLIFEVVRASDAGAYACVAKNRAGE 331



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 5/123 (4%)

Query: 2874 DTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEG 2933
            +++H + +     V     +R     + ++ +  YP P +I  +     + EG+   ++ 
Sbjct: 214  NSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYP-PRFI-QVPENMSIDEGRFCRMDF 271

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKL-TSDFGFVTLDLVDVYERDSGIYTCKAYNKR 2992
            +V     PD  + WY NG+ ++     K+  S+ G  +L    V   D+G Y C A N+ 
Sbjct: 272  KVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRA 329

Query: 2993 GEA 2995
            GEA
Sbjct: 330  GEA 332



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 8/96 (8%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSAN-RIQTYHDFG 1099
            PRF+  +     I EG+    + +V   P  D    V WY NG+ + S +       + G
Sbjct: 250  PRFI-QVPENMSIDEGRFCRMDFKVSGLPAPD----VSWYLNGRTVQSDDLHKMIVSEKG 304

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              +L    VRA D+G Y  VA+N AGEA  +  + V
Sbjct: 305  LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 340



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ-SGHRYRTSND-F 1899
            +AP FI +     K+ EG S   EC+I   P P  ++ W  N +++Q +  R     D  
Sbjct: 347  RAPMFIYKPQSK-KVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNT 403

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            G   L I  V  +D+G YT  A+N  G    + RL+V ++
Sbjct: 404  GRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 2/100 (2%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSI 4467
            + P+F  K Q  +V E +  + E +    P P + W R N  ++ N+    ++  +T  +
Sbjct: 347  RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 406

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
             L+I+ V  +D+  +   A N  G   C+  L V  +  Q
Sbjct: 407  TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQ 446



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 4/105 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E    P F   + + +SI EG F   + ++   G     V W  +GR V++       
Sbjct: 243  IQEKFYPPRF-IQVPENMSIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMI 299

Query: 962  FNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
             +  G  +L  + V   DAG Y C A N  G+AT +  L ++ K+
Sbjct: 300  VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 344



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 10/157 (6%)

Query: 1258 LGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA------- 1310
            LG  + +A+ +  + S      Q+     ++Q+     R     R D+    A       
Sbjct: 190  LGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYP 249

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY-EFDYVA 1369
            P+F +   N+   EG    ++ ++   G     V W+ NG+ +++    +    E    +
Sbjct: 250  PRFIQVPENMSIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 307

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
            L    V   D+G Y C A N+ GEA  +  L V+AK+
Sbjct: 308  LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 344



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 7/104 (6%)

Query: 1159 ESKFVEPMYQIEEISKSKPVFV-QPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
            E+ F   +  + +  K  P+F+ +P S    V EG ++ LEC++  +  P  ++ W  N 
Sbjct: 331  EATFTVQLDVLAKEHKRAPMFIYKPQSKK--VLEGDSVKLECQISAIPPP--KLFWKRNN 386

Query: 1218 RSVTVGS-RFKTYYD-FGFVALDIIHATSADTGEYTVRAVNHLG 1259
              V   + R   Y D  G V L I      D G YTV AVN  G
Sbjct: 387  EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 430



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY--DMGFV 3887
            P FI + +S  V E + V+ EC++     PKL   W RN +++       ++Y  + G V
Sbjct: 349  PMFIYKPQSKKVLEGDSVKLECQISAIPPPKL--FWKRNNEMVQFNTDRISLYQDNTGRV 406

Query: 3888 SLDILYVYAEDSGEYICRAVNDFG 3911
            +L I  V  +D+G Y   AVN+ G
Sbjct: 407  TLLIKDVNKKDAGWYTVSAVNEAG 430



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 9/124 (7%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF-HDFGI 3339
            PP+FI Q+ +   + EG+    + ++  +  PD  V W+ NG+ +     ++    + G+
Sbjct: 249  PPRFI-QVPENMSIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGL 305

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN-----LILDSQLPRGMEGGL 3394
              L        ++G Y CVA N+ G  +    L   +KE+      I   Q  + +EG  
Sbjct: 306  HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS 365

Query: 3395 EKLQ 3398
             KL+
Sbjct: 366  VKLE 369



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 10/127 (7%)

Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-THDFGYVALDILYTYAED 2178
            ++ EG     + +V  +  P   + W+ NG+ +++   ++    + G  +L      A D
Sbjct: 260  SIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 317

Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAG--HRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEE 2236
            +G Y C A N+ GEA  T  L V    H+   +    P   +K+     +G S ++E + 
Sbjct: 318  AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQS-KKV----LEGDSVKLECQI 372

Query: 2237 PKISPPR 2243
              I PP+
Sbjct: 373  SAIPPPK 379



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 9/133 (6%)

Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468
            D    +EK   P F     N+ ++ EG     + +++    P+  V WY NG+++++   
Sbjct: 239  DQDAIQEKFYPPRFIQVPENM-SIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDL 295

Query: 3469 FRTFC-DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN-----IILES 3522
             +    + G   L        D+G Y C A N  GEA  T  + V  K +      I + 
Sbjct: 296  HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP 355

Query: 3523 QLPKGMEGTIDKI 3535
            Q  K +EG   K+
Sbjct: 356  QSKKVLEGDSVKL 368



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS-RFKLTSD-FGFVTLDLVDVYER 2979
            +++EG  + LE Q+     P  K+ W  N ++++  + R  L  D  G VTL + DV ++
Sbjct: 359  KVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKK 416

Query: 2980 DSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            D+G YT  A N+ G    ++ +  T++ N
Sbjct: 417  DAGWYTVSAVNEAGVTTCNTRLDVTARPN 445



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ-SAARFHITFD-FGYVSLDIQHCVPED 2311
            V EG +   ECQ+  +  P L   +  N + +Q +  R  +  D  G V+L I+    +D
Sbjct: 360  VLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 417

Query: 2312 AGEYSVKAINALGHCTSAISMTVTAK 2337
            AG Y+V A+N  G  T    + VTA+
Sbjct: 418  AGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL-LTGSRVKTIND 3611
            E    P F   P    + E  S   EC++  +     ++ W  N + +     R+    D
Sbjct: 344  EHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQD 401

Query: 3612 -FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
              G V L I  V ++DAG YT  A N  G  T + +L V  R
Sbjct: 402  NTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF--D 2696
            ++AP+F    +S  K++EG  V LE Q+     P  K+ W +N   +       S +  +
Sbjct: 346  KRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDN 402

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             G VTL I  +   D+G YT  A N  G  V+T + +++
Sbjct: 403  TGRVTLLIKDVNKKDAGWYTVSAVNEAG--VTTCNTRLD 439



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 4/88 (4%)

Query: 2504 EFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THD 2562
            +F  P F QV    S + EG+    + +V   G P+    WY+NG  ++     +    +
Sbjct: 246  KFYPPRFIQVPENMS-IDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMIVSE 302

Query: 2563 FGFVTLDINSVVANDAGLYMCKAINRAG 2590
             G  +L    V A+DAG Y C A NRAG
Sbjct: 303  KGLHSLIFEVVRASDAGAYACVAKNRAG 330



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHD-FGYVALDIASVR 1109
            + K++EG S   E ++       +   W  N + +  + +RI  Y D  G V L I  V 
Sbjct: 357  SKKVLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVN 414

Query: 1110 AEDSGVYTVVARNAAGEAQLSASMTVETR 1138
             +D+G YTV A N AG    +  + V  R
Sbjct: 415  KKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVSLDITHTYEEDSG 2844
            EGD++  EC +  S  P  K+ W  NN+ +   T   S +  +   V+L I    ++D+G
Sbjct: 362  EGDSVKLECQI--SAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 419

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKN 2870
             YT  A N  G  T +  L  T   N
Sbjct: 420  WYTVSAVNEAGVTTCNTRLDVTARPN 445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 4084 IEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVM 4143
            + K R  EA++ V  + + +E K    P+F+  P +  V EG+  +  C+++  P P++ 
Sbjct: 324  VAKNRAGEATFTVQLDVLAKEHKRA--PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLF 381

Query: 4144 WLLNGNTI-VNGSRYKLTYD 4162
            W  N   +  N  R  L  D
Sbjct: 382  WKRNNEMVQFNTDRISLYQD 401



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT-V 3201
            + K   PRF    +N+  + +G+    +  V  +  PD  + WY NG+ ++     K  V
Sbjct: 244  QEKFYPPRFIQVPENMS-IDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIV 300

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            S+ G   L     +  D+G Y C A N+ GE
Sbjct: 301  SEKGLHSLIFEVVRASDAGAYACVAKNRAGE 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-DSSRITKTHDFGYV 2434
            P F Q  +N+ +I EG+    D ++   G P   V W+ N + ++ D        + G  
Sbjct: 250  PRFIQVPENM-SIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH 306

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
            S+    VR  D G Y C A N  GE
Sbjct: 307  SLIFEVVRASDAGAYACVAKNRAGE 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-DFGLVTLSINSLRNDDSGI 2714
            EG+   ++ +V     P+  + W+ NG T+ +    K    + GL +L    +R  D+G 
Sbjct: 263  EGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGA 320

Query: 2715 YTCKATNLLGEAVSTASIKI 2734
            Y C A N  GEA  T  + +
Sbjct: 321  YACVAKNRAGEATFTVQLDV 340



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFF-NFGYVALTIKSVTVHD 978
            + EG     E ++  I    L   W ++   V+ ++ RI+ +  N G V L IK V   D
Sbjct: 360  VLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 417

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTK 1004
            AG YT  A N  G  T +  L +  +
Sbjct: 418  AGWYTVSAVNEAGVTTCNTRLDVTAR 443


>AF133820-1|AAD29051.2|  498|Homo sapiens titin-like protein
           protein.
          Length = 498

 Score =  142 bits (344), Expect = 3e-32
 Identities = 70/207 (33%), Positives = 117/207 (56%), Gaps = 2/207 (0%)

Query: 374 TQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR 433
           T + +  ++  I EK   P+F++V ++  + EG+  R D +V+G P P+V+W++N R ++
Sbjct: 232 TSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ 291

Query: 434 DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
            D  HK++V+E G H+L+   V  SD+G   CVA+N++GE  F  +L+V+ KE   AP F
Sbjct: 292 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 351

Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDG-GASTLDIP 551
           + +  +  V EG+ V L  +    P P++ W+++   +  N + + ++ D  G  TL I 
Sbjct: 352 IYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK 411

Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578
                DA WY  +A N AG T    RL
Sbjct: 412 DVNKKDAGWYTVSAVNEAGVTTCNTRL 438



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 69/220 (31%), Positives = 103/220 (46%), Gaps = 17/220 (7%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTL 4571
            PP F    +N+++  G+  R+D KV+G    DV W  NG+ VQ  D+   I+ E G ++L
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
            +       D+G Y CVA N AGEA    +  V     K           AP  I +P + 
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHK----------RAPMFIYKP-QS 357

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK--PSKYFQMSRTADEYTLRISEAFPED 4689
            K V EG +++  C+I   P P + W + +++++    +           TL I +   +D
Sbjct: 358  KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 417

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVT-QPDQADNLPALTPLR 4728
             G Y   A N AG  T   +L VT +P+Q   LPA   LR
Sbjct: 418  AGWYTVSAVNEAGVTTCNTRLDVTARPNQ--TLPAPKQLR 455



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 58/210 (27%), Positives = 92/210 (43%), Gaps = 10/210 (4%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-- 4467
            PP F +  +   + E    R + +  G P P + WY     ++ S D      S K +  
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGLHS 307

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI   V   D+  +A VA+NR G A  +  L V  K  +       P F    Q+  V  
Sbjct: 308  LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR-----APMFIYKPQSKKVLE 362

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYE 4585
            G  V+L+ +++   P  ++W +N + VQ +     L +D  G  TLLI +   +D+G Y 
Sbjct: 363  GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 422

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
              A+N AG   C+    V+    +  P P+
Sbjct: 423  VSAVNEAGVTTCNTRLDVTARPNQTLPAPK 452



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 53/190 (27%), Positives = 93/190 (48%), Gaps = 13/190 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAH--YEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF- 3103
            PP F  V +++  I EG+     ++ S +P  D    + W+ NG+T+++    + + +  
Sbjct: 249  PPRFIQVPENM-SIDEGRFCRMDFKVSGLPAPD----VSWYLNGRTVQSDDLHKMIVSEK 303

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G+  L     + +D+G Y+C A N+ G+A  +V+L+ + K   + P F    Q+ + L +
Sbjct: 304  GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL-E 362

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST-RIKTVSD-FGFVVLDIAYTQNHDSGE 3221
            G S   EC +  +  P  K+ W  N + ++ +T RI    D  G V L I      D+G 
Sbjct: 363  GDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGW 420

Query: 3222 YVCRAYNKYG 3231
            Y   A N+ G
Sbjct: 421  YTVSAVNEAG 430



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 48/195 (24%), Positives = 81/195 (41%), Gaps = 3/195 (1%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP  I+  ++  + EG+      K+ G P P V WY   + ++     +M  +       
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 4682 ISEAF-PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I E     D G Y CVA N AG  T   +L V   +       +   +   V EG   + 
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGN--NAVLLIGNTYEEDTGTFTCRATTA 4798
            + QI++   P + W R   ++    D   +++ N     LLI +  ++D G +T  A   
Sbjct: 369  ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 428

Query: 4799 AGQVETSAKLVVKSK 4813
            AG    + +L V ++
Sbjct: 429  AGVTTCNTRLDVTAR 443



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 77/290 (26%), Positives = 122/290 (42%), Gaps = 50/290 (17%)

Query: 1791 LGEAVTSSTLFVQSKASLQLESQHESALQKIQ--QLEDSSRYQRREDV--EVAVNQA--- 1843
            LG    ++    Q  +  Q   QH S   ++Q    +  SR   R DV  + A+ +    
Sbjct: 190  LGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYP 249

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS-NDFGFA 1902
            PRFI Q+     + EG+    + ++   P P+  V WY NG+ +QS   ++   ++ G  
Sbjct: 250  PRFI-QVPENMSIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLH 306

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
            +L    V   D+G Y C A N  G+A  +++L+V +KE                      
Sbjct: 307  SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE---------------------- 344

Query: 1963 RYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ 2022
             +KRA       + KPQ      + +V EG  V LE  ++ +  P  ++ W  N   VQ 
Sbjct: 345  -HKRA----PMFIYKPQ------SKKVLEGDSVKLECQISAI--PPPKLFWKRNNEMVQF 391

Query: 2023 GHRFKTTY--DFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
                 + Y  + G V L I     +D G Y   A N  G  VTT + ++D
Sbjct: 392  NTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG--VTTCNTRLD 439



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 54/230 (23%), Positives = 98/230 (42%), Gaps = 32/230 (13%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TL 323
           PP+  Q P N  + EG   +   ++SG P P V+W+ NG+ + + + H++I +     +L
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                + SD+G Y  +A+N  G         V+    +    +   +I   Q        
Sbjct: 309 IFEVVRASDAGAYACVAKNRAG----EATFTVQLDVLAKEHKRAPMFIYKPQ-------- 356

Query: 384 EISEKALAPQFVKV-CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH-KIL 441
             S+K L    VK+ CQ               ++  P P++ W  N+  ++ + +   + 
Sbjct: 357 --SKKVLEGDSVKLECQ---------------ISAIPPPKLFWKRNNEMVQFNTDRISLY 399

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
            + +G   L+I +V   D+G  T  A N++G T    RL+V  +     P
Sbjct: 400 QDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 449



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 6/103 (5%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL-- 3747
            EK  PPRF +++ +N+ + EG     D +V   G P   + W+ NGR   +   +H +  
Sbjct: 245  EKFYPPRF-IQVPENMSIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDD-LHKMIV 300

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            ++ G  +L  + + A DAG Y C A N+ G AT T ++   AK
Sbjct: 301  SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 343



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL--TYDGMYHF 4167
            PP F+ +P+ ++++EG + R   +V+G P P V W LNG T+ +   +K+  +  G++  
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
                 R  D G    +             L V+ +
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 343



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 6/139 (4%)

Query: 1938 SKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK---PQFGKPIKNAEVTEGHP 1994
            +++S   +S+H         +   S  +  V D   + EK   P+F +  +N  + EG  
Sbjct: 207  AQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRF 266

Query: 1995 VHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCK 2053
              ++  ++ +  P   V WY NGR VQ     K    + G  +L      A D G Y C 
Sbjct: 267  CRMDFKVSGL--PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACV 324

Query: 2054 ATNAVGEAVTTSSVKVDAK 2072
            A N  GEA  T  + V AK
Sbjct: 325  AKNRAGEATFTVQLDVLAK 343



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 1/91 (1%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F Q+ +N    +G   + + K+ G P P VSW      +   + + M  +E+ G  S
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEK-GLHS 307

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L+ + +   D G Y C A+N+ GEA  +V +
Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQL 338



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 37/127 (29%), Positives = 66/127 (51%), Gaps = 7/127 (5%)

Query: 759 QESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
           Q++I+E+    P+FI+  +++  + EGR    + +++ +  P   V WY +GR + +   
Sbjct: 240 QDAIQEKFYP-PRFIQVPENMS-IDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDL 295

Query: 819 ITSIFNF-GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI--P 875
              I +  G  SL    +RA DAG+Y   A N+ GEA  T  + V A+    A + I  P
Sbjct: 296 HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP 355

Query: 876 EQRRYIE 882
           + ++ +E
Sbjct: 356 QSKKVLE 362



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/104 (29%), Positives = 54/104 (51%), Gaps = 4/104 (3%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS-NRLTTMHD-FG 1766
            +AP+F    +  +V E  +   E ++  +  PKL   W RN   ++ + +R++   D  G
Sbjct: 347  RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTG 404

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             V L +K VN +D+G YT  A+NE G    ++ L V ++ +  L
Sbjct: 405  RVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTL 448



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 12/134 (8%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG-HR 1492
            D++ +     P F+ +P+S + V+EG  V  EC++  +     K+ W +N + V     R
Sbjct: 339  DVLAKEHKRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDR 395

Query: 1493 FRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEA 1550
                 D  G V L I D+  +D+G YT  AVN  G        TC +  D+  R  Q   
Sbjct: 396  ISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGV------TTCNTRLDVTARPNQTLP 449

Query: 1551 GLEQIQVLEDRSKY 1564
              +Q++V    SKY
Sbjct: 450  APKQLRVRPTFSKY 463



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 4/97 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--FGYI 694
           P FI   +S   +EG  +  E +I  +  P  K+ W +N + ++ ++   S+++   G +
Sbjct: 349 PMFIYKPQSKKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNTGRV 406

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
           +L +  +N +D+G YT  AV+  GV      L VT R
Sbjct: 407 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 2/88 (2%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGDVS 130
           P+F    ++ +  +G + K E ++   P P + W R    +V+ N   +  Y + TG V+
Sbjct: 349 PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNE-MVQFNTDRISLYQDNTGRVT 407

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS 158
           LLIK +   D G YT +A N+ G   C+
Sbjct: 408 LLIKDVNKKDAGWYTVSAVNEAGVTTCN 435



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 7/114 (6%)

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPL 3600
            G V+      E   PP F   P ++ + E      + ++  +P  D    V W+ NG+ +
Sbjct: 235  GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPD----VSWYLNGRTV 290

Query: 3601 LTGSRVKTI-NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
             +    K I ++ G   L    V   DAG Y C A NR GEAT + +L V  ++
Sbjct: 291  QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 344



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 7/120 (5%)

Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           + ++  + P FI   Q    L EG +   E Q++ +  P  ++ W ++   +  ++   S
Sbjct: 341 LAKEHKRAPMFIYKPQSKKVL-EGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRIS 397

Query: 822 IF--NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRR 879
           ++  N G V+L I  +  +DAG YTV AVN+ G       + V AR   T  L  P+Q R
Sbjct: 398 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQT--LPAPKQLR 455



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY-DMGFV 3887
            PP+FI   ++ +++E    R + +V     P   + WY NG+ + S   ++ +  + G  
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLH 306

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGE 3912
            SL    V A D+G Y C A N  GE
Sbjct: 307  SLIFEVVRASDAGAYACVAKNRAGE 331



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 5/123 (4%)

Query: 2874 DTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEG 2933
            +++H + +     V     +R     + ++ +  YP P +I  +     + EG+   ++ 
Sbjct: 214  NSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYP-PRFI-QVPENMSIDEGRFCRMDF 271

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKL-TSDFGFVTLDLVDVYERDSGIYTCKAYNKR 2992
            +V     PD  + WY NG+ ++     K+  S+ G  +L    V   D+G Y C A N+ 
Sbjct: 272  KVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRA 329

Query: 2993 GEA 2995
            GEA
Sbjct: 330  GEA 332



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 8/96 (8%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSAN-RIQTYHDFG 1099
            PRF+  +     I EG+    + +V   P  D    V WY NG+ + S +       + G
Sbjct: 250  PRFI-QVPENMSIDEGRFCRMDFKVSGLPAPD----VSWYLNGRTVQSDDLHKMIVSEKG 304

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              +L    VRA D+G Y  VA+N AGEA  +  + V
Sbjct: 305  LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 340



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ-SGHRYRTSND-F 1899
            +AP FI +     K+ EG S   EC+I   P P  ++ W  N +++Q +  R     D  
Sbjct: 347  RAPMFIYKPQSK-KVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNT 403

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            G   L I  V  +D+G YT  A+N  G    + RL+V ++
Sbjct: 404  GRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 2/100 (2%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSI 4467
            + P+F  K Q  +V E +  + E +    P P + W R N  ++ N+    ++  +T  +
Sbjct: 347  RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 406

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
             L+I+ V  +D+  +   A N  G   C+  L V  +  Q
Sbjct: 407  TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQ 446



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 4/105 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E    P F   + + +SI EG F   + ++   G     V W  +GR V++       
Sbjct: 243  IQEKFYPPRF-IQVPENMSIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMI 299

Query: 962  FNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
             +  G  +L  + V   DAG Y C A N  G+AT +  L ++ K+
Sbjct: 300  VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 344



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 10/157 (6%)

Query: 1258 LGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA------- 1310
            LG  + +A+ +  + S      Q+     ++Q+     R     R D+    A       
Sbjct: 190  LGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYP 249

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY-EFDYVA 1369
            P+F +   N+   EG    ++ ++   G     V W+ NG+ +++    +    E    +
Sbjct: 250  PRFIQVPENMSIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 307

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
            L    V   D+G Y C A N+ GEA  +  L V+AK+
Sbjct: 308  LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 344



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 7/104 (6%)

Query: 1159 ESKFVEPMYQIEEISKSKPVFV-QPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
            E+ F   +  + +  K  P+F+ +P S    V EG ++ LEC++  +  P  ++ W  N 
Sbjct: 331  EATFTVQLDVLAKEHKRAPMFIYKPQSKK--VLEGDSVKLECQISAIPPP--KLFWKRNN 386

Query: 1218 RSVTVGS-RFKTYYD-FGFVALDIIHATSADTGEYTVRAVNHLG 1259
              V   + R   Y D  G V L I      D G YTV AVN  G
Sbjct: 387  EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 430



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY--DMGFV 3887
            P FI + +S  V E + V+ EC++     PKL   W RN +++       ++Y  + G V
Sbjct: 349  PMFIYKPQSKKVLEGDSVKLECQISAIPPPKL--FWKRNNEMVQFNTDRISLYQDNTGRV 406

Query: 3888 SLDILYVYAEDSGEYICRAVNDFG 3911
            +L I  V  +D+G Y   AVN+ G
Sbjct: 407  TLLIKDVNKKDAGWYTVSAVNEAG 430



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 9/124 (7%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF-HDFGI 3339
            PP+FI Q+ +   + EG+    + ++  +  PD  V W+ NG+ +     ++    + G+
Sbjct: 249  PPRFI-QVPENMSIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGL 305

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN-----LILDSQLPRGMEGGL 3394
              L        ++G Y CVA N+ G  +    L   +KE+      I   Q  + +EG  
Sbjct: 306  HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS 365

Query: 3395 EKLQ 3398
             KL+
Sbjct: 366  VKLE 369



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 10/127 (7%)

Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-THDFGYVALDILYTYAED 2178
            ++ EG     + +V  +  P   + W+ NG+ +++   ++    + G  +L      A D
Sbjct: 260  SIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 317

Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAG--HRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEE 2236
            +G Y C A N+ GEA  T  L V    H+   +    P   +K+     +G S ++E + 
Sbjct: 318  AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQS-KKV----LEGDSVKLECQI 372

Query: 2237 PKISPPR 2243
              I PP+
Sbjct: 373  SAIPPPK 379



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 9/133 (6%)

Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468
            D    +EK   P F     N+ ++ EG     + +++    P+  V WY NG+++++   
Sbjct: 239  DQDAIQEKFYPPRFIQVPENM-SIDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDL 295

Query: 3469 FRTFC-DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN-----IILES 3522
             +    + G   L        D+G Y C A N  GEA  T  + V  K +      I + 
Sbjct: 296  HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP 355

Query: 3523 QLPKGMEGTIDKI 3535
            Q  K +EG   K+
Sbjct: 356  QSKKVLEGDSVKL 368



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGS-RFKLTSD-FGFVTLDLVDVYER 2979
            +++EG  + LE Q+     P  K+ W  N ++++  + R  L  D  G VTL + DV ++
Sbjct: 359  KVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKK 416

Query: 2980 DSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            D+G YT  A N+ G    ++ +  T++ N
Sbjct: 417  DAGWYTVSAVNEAGVTTCNTRLDVTARPN 445



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ-SAARFHITFD-FGYVSLDIQHCVPED 2311
            V EG +   ECQ+  +  P L   +  N + +Q +  R  +  D  G V+L I+    +D
Sbjct: 360  VLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 417

Query: 2312 AGEYSVKAINALGHCTSAISMTVTAK 2337
            AG Y+V A+N  G  T    + VTA+
Sbjct: 418  AGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL-LTGSRVKTIND 3611
            E    P F   P    + E  S   EC++  +     ++ W  N + +     R+    D
Sbjct: 344  EHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQD 401

Query: 3612 -FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
              G V L I  V ++DAG YT  A N  G  T + +L V  R
Sbjct: 402  NTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF--D 2696
            ++AP+F    +S  K++EG  V LE Q+     P  K+ W +N   +       S +  +
Sbjct: 346  KRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPP--KLFWKRNNEMVQFNTDRISLYQDN 402

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             G VTL I  +   D+G YT  A N  G  V+T + +++
Sbjct: 403  TGRVTLLIKDVNKKDAGWYTVSAVNEAG--VTTCNTRLD 439



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 4/88 (4%)

Query: 2504 EFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THD 2562
            +F  P F QV    S + EG+    + +V   G P+    WY+NG  ++     +    +
Sbjct: 246  KFYPPRFIQVPENMS-IDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMIVSE 302

Query: 2563 FGFVTLDINSVVANDAGLYMCKAINRAG 2590
             G  +L    V A+DAG Y C A NRAG
Sbjct: 303  KGLHSLIFEVVRASDAGAYACVAKNRAG 330



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHD-FGYVALDIASVR 1109
            + K++EG S   E ++       +   W  N + +  + +RI  Y D  G V L I  V 
Sbjct: 357  SKKVLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVN 414

Query: 1110 AEDSGVYTVVARNAAGEAQLSASMTVETR 1138
             +D+G YTV A N AG    +  + V  R
Sbjct: 415  KKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVSLDITHTYEEDSG 2844
            EGD++  EC +  S  P  K+ W  NN+ +   T   S +  +   V+L I    ++D+G
Sbjct: 362  EGDSVKLECQI--SAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 419

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKN 2870
             YT  A N  G  T +  L  T   N
Sbjct: 420  WYTVSAVNEAGVTTCNTRLDVTARPN 445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 4084 IEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVM 4143
            + K R  EA++ V  + + +E K    P+F+  P +  V EG+  +  C+++  P P++ 
Sbjct: 324  VAKNRAGEATFTVQLDVLAKEHKRA--PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLF 381

Query: 4144 WLLNGNTI-VNGSRYKLTYD 4162
            W  N   +  N  R  L  D
Sbjct: 382  WKRNNEMVQFNTDRISLYQD 401



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT-V 3201
            + K   PRF    +N+  + +G+    +  V  +  PD  + WY NG+ ++     K  V
Sbjct: 244  QEKFYPPRFIQVPENMS-IDEGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIV 300

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            S+ G   L     +  D+G Y C A N+ GE
Sbjct: 301  SEKGLHSLIFEVVRASDAGAYACVAKNRAGE 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-DSSRITKTHDFGYV 2434
            P F Q  +N+ +I EG+    D ++   G P   V W+ N + ++ D        + G  
Sbjct: 250  PRFIQVPENM-SIDEGRFCRMDFKVS--GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH 306

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
            S+    VR  D G Y C A N  GE
Sbjct: 307  SLIFEVVRASDAGAYACVAKNRAGE 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF-DFGLVTLSINSLRNDDSGI 2714
            EG+   ++ +V     P+  + W+ NG T+ +    K    + GL +L    +R  D+G 
Sbjct: 263  EGRFCRMDFKVSGLPAPD--VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGA 320

Query: 2715 YTCKATNLLGEAVSTASIKI 2734
            Y C A N  GEA  T  + +
Sbjct: 321  YACVAKNRAGEATFTVQLDV 340



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFF-NFGYVALTIKSVTVHD 978
            + EG     E ++  I    L   W ++   V+ ++ RI+ +  N G V L IK V   D
Sbjct: 360  VLEGDSVKLECQISAIPPPKLF--WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 417

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTK 1004
            AG YT  A N  G  T +  L +  +
Sbjct: 418  AGWYTVSAVNEAGVTTCNTRLDVTAR 443


>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone RP11-465I11 on chromosome 1. ).
          Length = 5635

 Score =  129 bits (312), Expect = 2e-28
 Identities = 107/384 (27%), Positives = 161/384 (41%), Gaps = 35/384 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  ++ A  E    G P P   W ++  P+      +    S   IL I    + D   +
Sbjct: 2884 VLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRILQILNTQITDIGRY 2941

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGT 4540
              VAEN  G+AK   NL V           VPPS     ++N+ V     + L  +V+G 
Sbjct: 2942 VCVAENTAGSAKKYFNLNVH----------VPPSVIGPKSENLTVVVNNFISLTCEVSGF 2991

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P D+ WLKN + ++ +    I+   G  TL I+ A   D G+Y C+AIN AGE++    
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V +P       P  K  ++     E L    V EG ++   C+    P P + WYK  
Sbjct: 3050 LTVYVP-------PSIKDHDS-----ESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3097

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            ++I  S + ++   AD   L I +A   D G Y C A N AGR      L V  P   + 
Sbjct: 3098 RMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155

Query: 4721 LPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                 P R+++V     P       T    PTI WL+    I  +   ++      + L 
Sbjct: 3156 -----PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVE 4803
            I  +   D+G +TC A+   G+ +
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQ 3234



 Score =  119 bits (287), Expect = 2e-25
 Identities = 103/380 (27%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 1148

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 1149 LCVATNIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 1257 HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 1305

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   D   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 1306 EL--TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               +T   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 1364 KEQVT---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKL 1418

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 1419 FRATPEDAGRYSCKAINIAG 1438



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/371 (27%), Positives = 155/371 (41%), Gaps = 39/371 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + W R +  ++ +   +I T +  S L ++ V   D+  +  +  + GG++  S  L V+
Sbjct: 551  LTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E          PP  T+  +N + T G  V +    TG     + W  N   +    R +
Sbjct: 610  E----------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYR 659

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             +  DGT  L I  A P+D+G Y C+A NSAG                DK     +   A
Sbjct: 660  -MTSDGT--LFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEA 701

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P +++    + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+
Sbjct: 702  P-KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLK 758

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I E    D GDY CVA N AGR T    L V  P      PA     D+ +  G      
Sbjct: 759  IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLP 813

Query: 4742 TQITSKIKPTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              +    +PTI+W R +   I   P     I +     L I N +  D GT+ C A    
Sbjct: 814  CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 4800 GQVETSAKLVV 4810
            G++++   + V
Sbjct: 874  GKIQSETTVTV 884



 Score =  115 bits (276), Expect = 5e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 4237

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 4238 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 4287

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 4288 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 4344 YVKEP-------PVFKG-DYPSNWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 4388

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 4389 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 4441

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 4442 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 4497

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 4498 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score =  113 bits (271), Expect = 2e-23
 Identities = 103/405 (25%), Positives = 158/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 1227

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 1282

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + EDGT  L+I    P D+G+Y CVA+
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAV 1341

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDK---------------EQVTNVSVLLNQLTNLFCEVEG 1386

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 1387 TPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P      ++ V   +    + Q+     P I W ++G  L    P
Sbjct: 1445 NIDVLVPPTIIGTNFP-----NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 1500 NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  110 bits (264), Expect = 1e-22
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI-VPGGRTLQI 3022

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N+ G +K   +L V           VPPS     + +   VNV
Sbjct: 3023 IR-AKVSDGGEYTCIAINQAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 3071

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 3129

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 3174

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 3235 KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  109 bits (261), Expect = 3e-22
 Identities = 100/368 (27%), Positives = 151/368 (41%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 3271 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 3330

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         TL   ++N+        + + TGT P  + WLKNG  
Sbjct: 3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI--------ECRATGTPPPQINWLKNGLP 3382

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 3383 LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 3438

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 3439 ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 3486

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 3487 HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 3541

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 3542 VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 3598

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 3599 CLASSPAG 3606



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 3054 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI--LAD 3111

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 3112 GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 3161

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 3267

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 3268 CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L  +V         + + T    P I WL+ G  +P
Sbjct: 3328 EDRIFNLNVYVTPTIRGNKDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLP 3384

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 3385 LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 3420



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/407 (25%), Positives = 164/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 4043

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 4093

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMA 4150

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 4151 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 4194

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 4195 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 4250 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 4301

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+    + VK
Sbjct: 4302 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346



 Score =  106 bits (255), Expect = 2e-21
 Identities = 91/382 (23%), Positives = 165/382 (43%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P++ W ++  P+K + + +I     K  ++  Q    D   +  VA +  G
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAG 1719

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWL 4548
              +    + V          +VPP+     +     V    L+ LD  VTG+ P  + WL
Sbjct: 1720 EKEIKYEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWL 1769

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P  
Sbjct: 1770 KDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP-- 1825

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  K++         L +++V + + +   C   G P P++ W K D+ +  ++ 
Sbjct: 1826 -----PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ- 1871

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              +   +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L 
Sbjct: 1872 GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LN 1929

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            + V+    P Q + +      P I W ++  L+  +     ++ G   ++ I +    D 
Sbjct: 1930 ETVLV-SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDA 1986

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A  +AG  E    L V
Sbjct: 1987 GIYKCVAINSAGATELFYSLQV 2008



 Score =  105 bits (253), Expect = 3e-21
 Identities = 122/485 (25%), Positives = 195/485 (40%), Gaps = 59/485 (12%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            ++ G P P +SW + + P+    K +       G  +L I +    D GEYTC A NQ G
Sbjct: 2987 EVSGFPPPDLSWLKNEQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 154  EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
            E+      +VY+ P                   S ++E ++                  Y
Sbjct: 3043 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITW--------Y 3094

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
             NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 3095 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 3152

Query: 268  IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
            I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 3153 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIA 3212

Query: 327  NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 3213 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 3253

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                         D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 3254 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREG 505
            +  L I     SD+G  TCVA N +GE      LNV     +   K   E+  TL     
Sbjct: 3302 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTL---VD 3357

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              + +  RA GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A
Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVA 3415

Query: 566  QNVAG 570
             N AG
Sbjct: 3416 SNRAG 3420



 Score =  105 bits (252), Expect = 4e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 3420

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 3421 VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 3471 RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 3526

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 3527 -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 3573

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 3574 -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 3629

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 3687

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 3688 ANYTCVASNIAGKTTREFILTV 3709



 Score =  105 bits (251), Expect = 5e-21
 Identities = 101/395 (25%), Positives = 161/395 (40%), Gaps = 35/395 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP    + Q   V   +      + D  P P + W ++  P+   P   I     +S+L 
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTS 4527
            I    V+D+  +   A N  G  + + N+ +           VPP+   + +   + V  
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW----------VPPNIGGSDELTQLTVIE 2210

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G L+ L  + +G  P ++ W K G  V  D   ++    G   L I  A   D+  Y CV
Sbjct: 2211 GNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCV 2270

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG A+ +    V +  T       T + + P EI       IV  G++I   C++ 
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPT------ITNSGSHPTEI-------IVTRGKSISLECEVQ 2317

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PTV W K G  LIK +K  ++    + + L++      D G Y CVA N AG    
Sbjct: 2318 GIPPPTVTWMKDGHPLIK-AKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2374

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V  P     +       +I V E        + +    P+I W ++G  +  +  
Sbjct: 2375 KYDLSVHAPPSI--IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNS 2432

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +++  G   +L +  T  ED G +TC    AAG+
Sbjct: 2433 VRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score =  104 bits (250), Expect = 7e-21
 Identities = 109/409 (26%), Positives = 167/409 (40%), Gaps = 41/409 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 850

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 851  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 902

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 903  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 959

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 960  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 1003

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSS-AKFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYAK 1061

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +   L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V
Sbjct: 1122 PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score =  104 bits (250), Expect = 7e-21
 Identities = 96/377 (25%), Positives = 155/377 (41%), Gaps = 34/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P  +W + +  +  +P   + +  +   L I +V ++D   +  VA N  GT   +
Sbjct: 916  GNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT 972

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             ++VV           V P+     Q ++   G  V L  K +G     V W K G+ + 
Sbjct: 973  TSVVVH----------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                      DG+  L ++    ++SG+Y C A N+AG A+   +  V +       +P+
Sbjct: 1023 TSSAKFSAGADGS--LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYV-------RPR 1073

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT- 4674
                       +P++  ++A G+ +   C++   P P + W K  +LI P   F    T 
Sbjct: 1074 VFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITWAKETQLISP---FSPRHTF 1129

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +++I+E    D G Y CVA N AG VT A KL V  P +    P     + + V  
Sbjct: 1130 LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQV 1184

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            GQ             P I W + G+ +    D +      +  L I      D G +TC 
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCV 1242

Query: 4795 ATTAAGQVETSAKLVVK 4811
            AT  AG  ET   L V+
Sbjct: 1243 ATNIAGTDETEITLHVQ 1259



 Score =  104 bits (250), Expect = 7e-21
 Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKE 1817

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 1818 FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 1868 NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 1919

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK ++L+  S    M+  
Sbjct: 1920 SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFL 1970

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1971 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 2025

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +    DTG +TC 
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSAQISDTGRYTCV 2084

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 2085 AVNAAGEKQRDIDLRV 2100



 Score =  104 bits (250), Expect = 7e-21
 Identities = 102/369 (27%), Positives = 147/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W + +  I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 3237 YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 3286

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 3287 IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 3339

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +  L D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 3340 PTIRGNKDEAEKLMTLVDT------SINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 3391

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 3392 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 3448

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3506

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 3507 IASNEAGEV 3515



 Score =  104 bits (249), Expect = 9e-21
 Identities = 101/398 (25%), Positives = 164/398 (41%), Gaps = 40/398 (10%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVF 4474
            KM    V      + E +  G P+P+I WY++N  +  S      TF  +  +I I    
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSM---TFLNRGQIIDIESAQ 1982

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + D+ ++  VA N  G  +   +L V           V PS + +   V V     VRL+
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH----------VAPSISGSNNMVAVVVNNPVRLE 2032

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +  G     + WLK+G  V     N +    G   L +  A   D+G+Y CVA+N+AGE
Sbjct: 2033 CEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             + D +  V +                PP I+   ++  V   QA+E  C+    P PT+
Sbjct: 2092 KQRDIDLRVYV----------------PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135

Query: 4655 QWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             W K G  L+K      +S + +   L+I +A  +D G Y C A N AG+      + + 
Sbjct: 2136 TWLKDGHPLLKKP---GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHE 4772
             P    N+     L  + V EG       + +    P + W ++G+ ++ ++     I  
Sbjct: 2193 VP---PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS 2249

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G    L I    + D   ++C A+  AG  +    L V
Sbjct: 2250 GGRQ-LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286



 Score =  102 bits (245), Expect = 3e-20
 Identities = 96/389 (24%), Positives = 155/389 (39%), Gaps = 31/389 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  +   R E E  G P P + W ++  P+ +  +  +   S   IL +    + D+  +
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRY 2081

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G  +   +L V           VPP+     QNV+V   Q V L  +     
Sbjct: 2082 TCVAVNAAGEKQRDIDLRV----------YVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  + WLK+G  +       I E      L I +A  QD+G+Y C A N AG+   +   
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNVAGKTEKNYNV 2189

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             + +P       P    +       + L    V EG  I   C+  G P P + W K   
Sbjct: 2190 NIWVP-------PNIGGS-------DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +      ++   +    L+IS A   D   Y CVA N AG       L+V       N 
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
             +     +I+V  G+    + ++     PT+ W+++G  + +    +++ EG+  +L + 
Sbjct: 2296 GSHPT--EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQLK 2351

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            N +  DTG + C A   AG  +    L V
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380



 Score =  101 bits (243), Expect = 5e-20
 Identities = 101/380 (26%), Positives = 148/380 (38%), Gaps = 35/380 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 1006 GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPGG-EESGEYVCTATNTAGYAKRK 1063

Query: 4496 ANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V  + R    + G+           ++V +G+ V L  +V    P  + W K  + 
Sbjct: 1064 VQLTVYVRPRVFGDQRGLSQDK----PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 1119

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P          G+  + I E    DSG Y CVA N AG      +  V          
Sbjct: 1120 ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV---------- 1167

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S 
Sbjct: 1168 ------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIV 4731
               + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V
Sbjct: 1222 P--DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 1279

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                Q  +F        KPTI+WL  G  L    P   ++ +G   +L+I +    D G 
Sbjct: 1280 A--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGE 1335

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A   AG  E    L V
Sbjct: 1336 YICVAVNEAGTTERKYNLKV 1355



 Score =  101 bits (241), Expect = 8e-20
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 3912

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 3970

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 3971 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 4013

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 4014 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 4071

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 4072 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 4126 RVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 1242 VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 1293

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 1294 PKPTIKWLHNGRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 1353 LKVH----------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 1400

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 1453

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 1506

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 1507 GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 1561

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 1562 NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 1619

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 1620 VANVAGTAEKS 1630



 Score =  100 bits (239), Expect = 1e-19
 Identities = 106/423 (25%), Positives = 169/423 (39%), Gaps = 31/423 (7%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKK-MQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T +   A  +ER + G      P I  +  ++  +V E +      E  G P+P I W++
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK 2515

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRR 4505
            +  P++   D   H  S    L I  V V  +  +  +A +  G    S +L V      
Sbjct: 2516 DGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
             G G    P      ++V V       L  +     P  + W K+G  ++ +   +IL  
Sbjct: 2574 AGVGSDGNP------EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL-- 2625

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             G  TL IL A   ++G+Y CVA N AGE     E  V +P   +K         +P E+
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL-SPKEV 2684

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
                K K+      +   C+    P  ++ WYK  + +K   +  ++  A+ +TL+I EA
Sbjct: 2685 ----KIKV---NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA--ANGHTLQIKEA 2735

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-------VVYEGQPA 4738
               D G Y CVA N AG   +   + +  P     L  +  + D         V    P 
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +  +   PT+ W ++G   P T   +++      VL I     ED G +TC A   
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNE 2853

Query: 4799 AGQ 4801
            AG+
Sbjct: 2854 AGE 2856



 Score =   99 bits (238), Expect = 2e-19
 Identities = 82/299 (27%), Positives = 123/299 (41%), Gaps = 40/299 (13%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P    +  G     + ++ G P P VTW K+G  LI +   EI+    H  L+++N   S
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGH-ILQLKNIHVS 2356

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            D+G Y  +A N  G       L+V +P  S + + RS                       
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHRS----------------------- 2392

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ + V +   V+        C  +G P P +TWF +   +    + +IL   SG   L 
Sbjct: 2393 PENISVVEKNSVS------LTCEASGIPLPSITWFKDGWPVSLSNSVRIL---SGGRMLR 2443

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +   T+ D+G  TCV RN +GE      L+V+    +V    +E    + V+E + V L 
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE---DVKVKEKQSVTLT 2500

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG P+    +   H   G   L I   +      Y C A + AG
Sbjct: 2501 CEVTGNPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 35/375 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E E  G P P + W ++  P+  +   +I       IL ++ + V D+  +  VA N  G
Sbjct: 2313 ECEVQGIPPPTVTWMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT---LTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
                  +L V            PPS      + +N++V     V L  + +G     + W
Sbjct: 2371 MTDKKYDLSVH----------APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITW 2420

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G  V   + N +    G   L +++   +D+G+Y CV  N+AGE R      V +P 
Sbjct: 2421 FKDGWPVS--LSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP- 2477

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                  P     N        L+D  V E Q++  +C++ G P+P + W+K  + ++  +
Sbjct: 2478 ------PHIVGENT-------LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               +   +    L+I+       G Y C+A + AG  + +  L V        + +    
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
             D+ V    P     +  S    TI W ++G  +    + +++  G    +L  N  E++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL--NAQEDN 2640

Query: 4788 TGTFTCRATTAAGQV 4802
             G ++C AT  AG++
Sbjct: 2641 AGRYSCVATNEAGEM 2655



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 95/380 (25%), Positives = 157/380 (41%), Gaps = 34/380 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E +  P P + WY++  P+ +S    I       +L I +  VED+  +  VA N  G  
Sbjct: 2800 ETNAAPPPTLTWYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857

Query: 4493 KCSANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                ++ V+     +G    +P       + V V   +   ++   +G+      W K+G
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLP-------EEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2910

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            + +  D  +K L       L IL     D G+Y CVA N+AG A+               
Sbjct: 2911 QPLLEDDHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAK--------------- 2953

Query: 4612 PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             K      + PP +I P  + + V     I  +C++ G P P + W K ++ IK +    
Sbjct: 2954 -KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +       TL+I  A   D G+Y C+A N AG       L V  P    +  + + L  +
Sbjct: 3013 I--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-LSVV 3069

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG     + +  +   P I W + G +I E+   +++ +G   +L I      DTG 
Sbjct: 3070 NVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQ 3127

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + CRA   AG+ + +  L V
Sbjct: 3128 YVCRAINVAGRDDKNFHLNV 3147



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 88/301 (29%), Positives = 127/301 (42%), Gaps = 37/301 (12%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 1051

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 1052 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 1090

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 1091 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 1143

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 579  Y 579
            +
Sbjct: 1257 H 1257



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF 4137

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 4138 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 4184

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 4185 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 4241

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 4242 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 4286 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKAIG 4341

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 4394

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 4395 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 88/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 1227

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 1268

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 1269 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 1318

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
             G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ + ++V  
Sbjct: 1319 DGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVTNVSVLL 1374

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 1375 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCK 1432

Query: 565  AQNVAGST 572
            A N+AG++
Sbjct: 1433 AINIAGTS 1440



 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 96/388 (24%), Positives = 160/388 (41%), Gaps = 36/388 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E        E  G PLP I W+++ +P+  S   +I   S   +L + Q  +ED+  +
Sbjct: 2398 VVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRMLRLMQTTMEDAGQY 2455

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTG 4539
              V  N  G          EE++  G   +VPP      T ++V V   Q V L  +VTG
Sbjct: 2456 TCVVRNAAG----------EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                ++ W K+G+ +Q D  + I+   G   L I       +G+Y C+A + AG      
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
               V +      P      ++  PE      D  V         C+    P  T+ W+K 
Sbjct: 2564 SLNVFV-----SPTIAGVGSDGNPE------DVTVILNSPTSLVCEAYSYPPATITWFKD 2612

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP---D 4716
               ++ ++  ++       TL+I  A  ++ G Y CVA N AG +    ++KV  P   +
Sbjct: 2613 GTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2670

Query: 4717 QADNL-PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
            + D   P L+P +++ +        + +  +    ++ W ++G   P   D  +    N 
Sbjct: 2671 KGDLWGPGLSP-KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ--PLKSDDHVNIAANG 2727

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              L I      DTG +TC A+  AG+ E
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDE 2755



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 64/209 (30%), Positives = 88/209 (42%), Gaps = 8/209 (3%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYP 421
            +   QY    +    EER       L P  +      +D  V E +     C VTG P P
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            E+TW  + + +++D  H I+   SG   L ITNV +  +G  TC+A + +G  +    LN
Sbjct: 2510 EITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V     +           + V    P  L   A   P   ITW KDG P+  N  +RI  
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2626

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G  TL I  A+  +A  Y C A N AG
Sbjct: 2627 --GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 3896

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 3951

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 4006

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 4007 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 4065 GTALGKIKL 4073



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 99/397 (24%), Positives = 159/397 (40%), Gaps = 41/397 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N  V  
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1934

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+ + +        L       + I  A   D+G Y+CV
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1992

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1993 AINSAGA----TELFYSL------------QVHVAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++ A   D G Y CVA N+AG    
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 2095 DIDLRVYVPPN-----IMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              +    N +VL I +   +DTG +TC AT  AG+ E
Sbjct: 2150 LSI--SENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 96/379 (25%), Positives = 156/379 (41%), Gaps = 42/379 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W   +  I  S  +++ +  T   L I+    +D+ ++  +A N  GT K +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            + L   E           P   +    + V  G +  ++ K +G  P  V W K   +++
Sbjct: 694  STLRYIEA----------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P   +  L  D    LL I E    D+G Y CVAIN AG A                   
Sbjct: 744  P---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI--------------- 785

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             T    +PP  I+   D  +  G  +   C + G P PT++W + D +   S+ F +S  
Sbjct: 786  -TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 4675 ADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +   T  L I   +  D+G Y C A N  G+  + ++  VT       L  ++P    V+
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK--IQSETTVTVTGLVAPLIGISPSVANVI 902

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQ      T +     P  +W++  A++ + P   +  +G+   L I     +D G +
Sbjct: 903  -EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEY 958

Query: 4792 TCRATTAAGQVETSAKLVV 4810
            TC A+  AG    +  +VV
Sbjct: 959  TCVASNVAGTNNKTTSVVV 977



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 86/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ +  G     + W 
Sbjct: 1533 KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY 1582

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 1583 KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 1638

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   CK  G P P + W K    +K +  
Sbjct: 1639 -----PMIEG-----NLATPLNKQVVI-AHSLTLECKAAGNPSPILTWLKDGVPVKANDN 1687

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             ++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 1688 IRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 1742

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G LI E   F+++  G    L+I      +T
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNT 1800

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTV 1822



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V+G P P+++W  N++ I+ + N  I+    G   L I    +SD G  TC+A N++G
Sbjct: 2986 CEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 3043 ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3101

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 3102 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 3137



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 87/367 (23%), Positives = 146/367 (39%), Gaps = 17/367 (4%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W+++  P++++ + +I        L I     +++  ++ VA N  G       
Sbjct: 2603 PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V       +G +  P   L+ + V +     + L+ +        + W K+G+ ++ D
Sbjct: 2661 VKVYIPPIINKGDLWGPG--LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2718

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                I      +TL I EA   D+G+Y CVA N AGE   D +  + +P +  K      
Sbjct: 2719 DHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
              +         KD I+     I   C+    P PT+ WYK G  L    K   +     
Sbjct: 2777 MLDTGRN--GEAKDVII--NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PG 2829

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L+I  A  ED G Y CVA N AG  ++   ++V  P       +  P  ++ V   +
Sbjct: 2830 GRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP-EEVTVLVNK 2888

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  +   +    P   W ++G  + E    + +   N  +L I NT   D G + C A 
Sbjct: 2889 SALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRILQILNTQITDIGRYVCVAE 2946

Query: 4797 TAAGQVE 4803
              AG  +
Sbjct: 2947 NTAGSAK 2953



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 3607

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 3608 -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 3661

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 3662 LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 3712

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 3713 PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 3762

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 3763 LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 3815

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 3816 IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 3875

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 3876 CTVTNGAGDDKRTVDLTVQ 3894



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 3553 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 3602

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 3603 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 3640

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
              +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 3641 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 3696

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 3697 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 3752 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 4064

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 4065 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 4119

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 4120 VESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 1835 ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 1892

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 1893 AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1947

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1948 PVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 2000



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 13/217 (5%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
            R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  + + I +    KIL+N      L+I    +S++G+  C+A N +G+   +  + V 
Sbjct: 1767 MWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTD 542
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I + 
Sbjct: 1824 VPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSS 1879

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 1880 G--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 49/290 (16%)

Query: 293  PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGY 352
            P   +TWFK+G  L ++    I+      TL++ N Q+ ++G Y+ +A N  G ++    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            + V  P                       + ++    L+P+ VK+  +  +T       +
Sbjct: 2661 VKVYIPP-------------------IINKGDLWGPGLSPKEVKIKVNNTLT------LE 2695

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C     P   ++W+ + + ++ D +  I  N    H L I    +SD+G  TCVA N +G
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAG 2752

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNV----REGE--------PVVLNARAVGTPTP 520
            E      +N+      V P F + +   N+    R GE        P+ L       P P
Sbjct: 2753 EDELDFDVNI-----QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2807

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +TW KDG P+  + ++ I    G   L IPRAK  DA  Y C A N AG
Sbjct: 2808 TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAG 2855



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 52/350 (14%)

Query: 229 RLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGAD 282
           R L  +S   +S+     GE    +S+E   S   V      PPK+   P+N     G++
Sbjct: 569 RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSE 628

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
                  +G P+P++ W  N   ++ S+++ + +     TL ++N    D+G Y      
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY------ 679

Query: 343 PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
             GC+ ++      + T+              +Q  T   IE      AP+ + V  +  
Sbjct: 680 --GCLASNS-----AGTD--------------KQNSTLRYIE------APKLMVVQSELL 712

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L I      D+G 
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGD 769

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TCVA N++G    +  L+V        P F++  + +++  G  V L     G P P I
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI 824

Query: 523 TWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            W++ D +PI   P  +   +      L I    ASD   Y C A+N  G
Sbjct: 825 KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFG 874



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/302 (24%), Positives = 132/302 (43%), Gaps = 33/302 (10%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P+  K++       + +    P   ++W+K+GQ L  S+ H  I  + HT L+++  Q S
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANGHT-LQIKEAQIS 2738

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR--ETEERIEISEKA 389
            D+G YT        C+ ++  +A E   +  V  Q    +  + Q+  E    ++     
Sbjct: 2739 DTGRYT--------CVASN--IAGEDELDFDVNIQ----VPPSFQKLWEIGNMLDTGRNG 2784

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
             A         +DV         C     P P +TW+ +   +    + K+L+   G   
Sbjct: 2785 EA---------KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS--SDKVLILPGGR-V 2832

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I    + D+G  TCVA N++GE + Q  + V+    ++     +    + V   +  +
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSAL 2891

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +   + G+P PR +WQKDG P++ +   +  ++G    L I   + +D   Y C A+N A
Sbjct: 2892 IECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNG--RILQILNTQITDIGRYVCVAENTA 2949

Query: 570  GS 571
            GS
Sbjct: 2950 GS 2951



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/311 (23%), Positives = 128/311 (41%), Gaps = 40/311 (12%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 3304 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 3348

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               +EK +         D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 3349 ---AEKLMT------LVDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLL- 3392

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 3393 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 3448

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 3449 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 3505

Query: 563  CTAQNVAGSTA 573
            C A N AG  +
Sbjct: 3506 CIASNEAGEVS 3516



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 3625 TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 3682

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 3683 DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 3732

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 3790

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 3791 TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 3895 VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 3950 GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 3984



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 3769

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 3819

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 3880 NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 3923

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 3980

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 3981 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4035

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 4036 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 9/163 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 2030 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSAQISDTGRYTCVAVN 2087

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 2088 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 2142

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P++  P L I  +   S L I  A+  D   Y C A NVAG T
Sbjct: 2143 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKT 2183



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 722  ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 779

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 780  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 829

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 830  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 885

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 886  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 936  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 986

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 987  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPGGE 1044

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 60/204 (29%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 380  EERIEISEKALAPQFVK-----VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            E+ ++   + L P  +K     + ++  V   K    +C  +G P P  +W  + + + +
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
            D +HK L N      L I N  ++D G   CVA N +G       LNV     V+ PK  
Sbjct: 2916 DDHHKFLSN---GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-- 2970

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
                 L V     + L     G P P ++W K+  PI  N    I    G  TL I RAK
Sbjct: 2971 --SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAK 3026

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD   Y C A N AG +  +  L
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSL 3050



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 101/475 (21%), Positives = 177/475 (37%), Gaps = 49/475 (10%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W +   P V   + +++  + +G V  + K +   D G YTC A N  GE  
Sbjct: 1852 GIPNPSITWLKDDQP-VNTAQGNLKI-QSSGRVLQIAKTLLE-DAGRYTCVATNAAGETQ 1908

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              + +                    VS  V+ +           +        +  T  +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
              +  ++   E   + +    + +     G      +TE+  SL     P I+       
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAG------ATELFYSLQVHVAPSISGSNNMVA 2022

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +      + + +  G P P +TW K+G   ++S  + +        L + + Q SD+G Y
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSP-VSSFSNGLQVLSGGRILALTSAQISDTGRY 2081

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T        C+      AV +  E              +QR+ + R+ +    +  +   
Sbjct: 2082 T--------CV------AVNAAGE--------------KQRDIDLRVYVPPNIMGEE--- 2110

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              Q+  V   +     C+    P P +TW  +   +       I  N S    L I +  
Sbjct: 2111 --QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---VLKIEDAQ 2165

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            + D+G  TC A N +G+T     +N+     +      +  + L V EG  + L   + G
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGS---DELTQLTVIEGNLISLLCESSG 2222

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             P P + W+K G P++ +   R+    G   L I  A+ SDAA Y C A NVAG+
Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 3503

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 3560

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 3561 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
            P  V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 1460 PNEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 1510

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 1567

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 1568 ECETRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 1625

Query: 571  S 571
            +
Sbjct: 1626 T 1626



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/281 (24%), Positives = 114/281 (40%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 1851 NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 1901

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 1902 NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1938

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+ ++R +    +   L   +    + I +  +SD+G+  CVA N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQIIDIESAQISDAGIYKCVAIN 1995

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1996 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +  A+ SD   Y C A N AG
Sbjct: 2051 P-VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 2090



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 13/177 (7%)

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            V  D  V    + + +C   G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 1553 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 1609

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
            +SDS   TC   N +G       ++V      V P      +T LN  V     + L  +
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECK 1664

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P+P +TW KDGVP+  N  +RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 12/168 (7%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 4236

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G
Sbjct: 4292 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 4315

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K    + V+E          PP F     +  +    G
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE----------PPVFKGDYPSNWIEPLGG 4365

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 4366 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 4421

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 4422 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 4464

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 4465 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 4520



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 52/187 (27%), Positives = 81/187 (43%), Gaps = 11/187 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+   + +++  T G      C  TG P P++ W +ND  I   + +++    + +  L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM----TSDGTLF 667

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V+ 
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVME 722

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N AG 
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGR 780

Query: 572 TATRARL 578
              +  L
Sbjct: 781 ATGKITL 787



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
            L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 1307 LTGREPGISILEDGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 1363

Query: 398  CQ---DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
             +   +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GKILKLFR 1420

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
             T  D+G  +C A N +G +     ++V+    ++   F    S +  R+   V L  + 
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD---VALECQV 1477

Query: 515  VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 1533

Query: 572  TATRARL 578
             A   +L
Sbjct: 1534 QAKDIKL 1540



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 909

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 966

Query: 570 GS 571
           G+
Sbjct: 967 GT 968



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 4426 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 4480

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 4481 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 4521



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG +    C  +G P P + W      +  D   ++ +  SG   L I+    SD+ +
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL-SGGRQLQISIAEKSDAAL 2266

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             +CVA N +G    +  L V  +  +         + + V  G+ + L     G P P +
Sbjct: 2267 YSCVASNVAGTAKKEYNLQVYIRPTIT--NSGSHPTEIIVTRGKSISLECEVQGIPPPTV 2324

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            TW KDG P+I    + I  +G    L +     SD   Y C A NVAG T
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAVNVAGMT 2372



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 4314

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G   F   +  +  ++   P F   + +  +   G   +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG---FVKAIGFVYVKE--PPVFKGDYPSNWIEPLGGNAIL 4369

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/345 (22%), Positives = 130/345 (37%), Gaps = 37/345 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I +V + D   +  +A +  GT +      V E          PP       NV VT 
Sbjct: 484  LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE----------PPPVIQVPNNVTVTP 533

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L   +      ++ W +N + V+     +I       +L +      D+G+Y C+
Sbjct: 534  GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCM 592

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              +  G +       V                  PP++    K++    G  +   C   
Sbjct: 593  VSSEGGSSAASVFLTVQ----------------EPPKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P P + W   D  I  S  ++M  T+D  TL I  A P+D G Y C+A NSAG     
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRM--TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            + L+  +  +      +    +++V  G     + + +    P ++W +    +   P  
Sbjct: 694  STLRYIEAPK-----LMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPST 746

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +I +    +L I  T + D G +TC A   AG+      L V S
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D  V     T   C     P   +TWF +   +  + N +IL    G   L I N    
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQED 2639

Query: 459  DSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            ++G  +CVA N++GE      + V     I K  +  P    +   + ++    + L   
Sbjct: 2640 NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE 2697

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   P+  ++W KDG P+  +  + I  +G   TL I  A+ SD   Y C A N+AG
Sbjct: 2698 AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAG 2752



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 3762 ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 3876

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 3877 TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 3932 KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 74/294 (25%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            +G+         G P P + W ++GQ L   + H  ++TH    L++   +  DSG YT 
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG-MVLQLLKAETEDSGKYTC 3506

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            +A N  G +     L V  P           +I  +++ E     EIS     P     C
Sbjct: 3507 IASNEAGEVSKHFILKVLEP----------PHINGSEEHE-----EISVIVNNP-LELTC 3550

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                +   KMT       GRP P+        Q++            G   L I+   + 
Sbjct: 3551 IASGIPAPKMTWMK---DGRPLPQTD------QVQ---------TLGGGEVLRISTAQVE 3592

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G  TC+A + +G+   +  + V     +         + L  R+   V L  ++   P
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ---VTLECKSDAVP 3649

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P ITW ++G  +   P +RI +  G   L I  A   D A Y C A N+AG T
Sbjct: 3650 PPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGKT 3701



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L I  V   D+G  TC+
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQIAFVQPGDAGHYTCM 4149

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 4150 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4204

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 4205 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 61/277 (22%), Positives = 112/277 (40%), Gaps = 28/277 (10%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            ++   V    P  + +++NG  +  D   + L+E  +  L I +    D G YEC+A++S
Sbjct: 448  QIPCSVDSLLPFTLSFVRNGVTLGVD---QYLKESASVNLDIAKVTLSDEGFYECIAVSS 504

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG  R      VS                 PP +I+   +  V  G+    +C I+    
Sbjct: 505  AGTGRAQTFFDVS----------------EPPPVIQVPNNVTVTPGERAVLTCLIISAVD 548

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
              + W + D+ ++ ++  ++ RT    +L +      D G+Y C+  +  G    +  L 
Sbjct: 549  YNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            V +P +   +P     ++     G         T   KP I W      I  +  ++M  
Sbjct: 608  VQEPPKVTVMP-----KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            +G    L I N   +D G + C A+ +AG  + ++ L
Sbjct: 663  DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 12/201 (5%)

Query: 402  DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
            +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 955

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 956  GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 1010

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             + W K G  +I     +  + G   +L +      ++  Y CTA N AG    + +L  
Sbjct: 1011 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068

Query: 581  XXXXXXXXXQKRLHLPRPTKV 601
                     Q+ L   +P ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEI 1089



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 12/188 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++V  +  VT G+     C +       +TW  NDR +R        +    N +L 
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVL 510
           + +V  +D+G   C+  ++ G +A    L V E  +V V PK        +   G  V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK------NQSFTGGSEVSI 631

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P+I W  + + I+ +   R+ +DG   TL I  A   DA  Y C A N AG
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688

Query: 571 STATRARL 578
           +    + L
Sbjct: 689 TDKQNSTL 696



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N+ G+++    L   
Sbjct: 2996 LSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   EC    V  P   I WY NG+ +  ST ++ 
Sbjct: 3054 VPPSIKDHDSESLSVVNV---REGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEI 3108

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 3109 LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 104/477 (21%), Positives = 174/477 (36%), Gaps = 55/477 (11%)

Query: 99   PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            P P ++W +   PL   +K  +      G   L I +    D G YTC A N+ GE    
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLIL----PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860

Query: 159  ----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                V + P                 + S  +E  + G+        +  Q +   +   
Sbjct: 2861 YDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--H 2918

Query: 215  HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
            H    + ++       + ++     + +   G +    +  +      V P  I  K  N
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-----VPPSVIGPKSEN 2973

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
              +          ++SG P P ++W KN Q  I  N + +I      TL++   + SD G
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQP-IKLNTNTLIVPGGR-TLQIIRAKVSDGG 3031

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERIEISEKALAPQ 393
             YT +A N  G       L V  P    ++D  S+ ++    RE T   +E    A+ P 
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSLECESNAVPPP 3089

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
             +   ++     G+M      +T   + E+   + D Q+   +  K  V+++G +     
Sbjct: 3090 VITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVSDTGQYVCRAI 3133

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV               +G       LNV     +  P+      T++     PV L   
Sbjct: 3134 NV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS----NPVTLTCD 3174

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C A N+ G
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 4432 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 4482

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 4483 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 4531



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C+  G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 1718

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  I
Sbjct: 1719 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 1776 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 1812



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 1238

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
             TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 1239 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 1296

Query: 521  RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W  +G  +    P + I  DG  + L I      D   Y C A N AG+T  +  L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 14/157 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA----EISVK 3137
            I WF +G  +E++  IR +   G   L+IL  +  ++G YSC ATN+ G+     E+ V 
Sbjct: 2607 ITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVY 2664

Query: 3138 L-ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +   ++K     P  +   + ++ +K   +   EC    +  P   + WY +GQP++   
Sbjct: 2665 IPPIINKGDLWGPGLSP--KEVK-IKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDD 2719

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +   ++ G   L I   Q  D+G Y C A N  GED
Sbjct: 2720 HVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGED 2754



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 62/288 (21%), Positives = 104/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 4132

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 4133 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4192

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 4193 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 4250

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 4251 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 4303

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +   G++ V+ P
Sbjct: 4304 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 3515

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 3516 SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3569

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 3570 PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 3608



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +  S  IR + A G V+  I+  + +D   Y+C A+N+ G    
Sbjct: 3367 TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYTCVASNRAGVDNK 3424

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L+            T  I  ++    G S    C       P M   W  +GQP+  
Sbjct: 3425 HYNLQVFAPPNMDNSMGTEEITVLK----GSSTSMACITDGTPAPSM--AWLRDGQPLGL 3478

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + TVS  G +VL +   +  DSG+Y C A N+ GE
Sbjct: 3479 DAHL-TVSTHG-MVLQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 17/203 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +L+IL T+ TD G Y C A N  G A+   ++ +       G K    T + N       
Sbjct: 2927 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN------- 2979

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                  C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C
Sbjct: 2980 NFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTC 3035

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----E 3280
             A N+ GE   + ++  Y    +     +  S+  +RE  S+    +     P      +
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3095

Query: 3281 PPKFITQIQDVTKLVEGQSAHFE 3303
              + IT+   V  L +GQ  H +
Sbjct: 3096 NGRMITESTHVEILADGQMLHIK 3118



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 64/257 (24%), Positives = 98/257 (38%), Gaps = 22/257 (8%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P + W +K +P++  +   +R    +G   L I      D   Y+C A N  G A 
Sbjct: 2222 GIPPPNLIWKKKGSPVLTDSMGRVRI--LSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279

Query: 157  ----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
                  VYI+P                R  S ++E +  G    T    +    +    G
Sbjct: 2280 KEYNLQVYIRPT-ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG 2338

Query: 213  TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES-DVQISTEIDRSLGPVSPPKIA-- 269
             +            E  +L+  +   S T RYV  + +V   T+    L   +PP I   
Sbjct: 2339 VEILD---------EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389

Query: 270  -QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             + P N  + E        + SG P P +TWFK+G  +  SN   I++      LR+  T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQT 2447

Query: 329  QKSDSGHYTLLAENPNG 345
               D+G YT +  N  G
Sbjct: 2448 TMEDAGQYTCVVRNAAG 2464



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 3728 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 3784

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 3785 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 3883



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           + ES +  L I  VTLSD G   C+A + +G    Q   +V E      P  ++  + + 
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE-----PPPVIQVPNNVT 530

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V  GE  VL    +      +TWQ++   +      RI T    S L++   K +DA  Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEY 589

Query: 562 QCTAQNVAGSTA 573
            C   +  GS+A
Sbjct: 590 HCMVSSEGGSSA 601



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 260  LGPVSPPKIAQKP--RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            L  + PP I  +    + K++E        +++GNP P +TW K+GQ L     H II+ 
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS- 2530

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L++ N Q   +G YT LA +P G
Sbjct: 2531 -GGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 86/218 (39%), Gaps = 35/218 (16%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            ++ IK       E     I  ++L   W KDG+P+++   +    N G+  L IK   + 
Sbjct: 2683 EVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQIS 2738

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEV 1037
            D G YTC A N  G+     ++ I          Q P   +K+  + +     +  E + 
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI----------QVPPSFQKLWEIGNMLDTGRNGEAKD 2788

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD 1097
             I   P                S + E    P   LT    WY +G  +TS++++     
Sbjct: 2789 VIINNP---------------ISLYCETNAAPPPTLT----WYKDGHPLTSSDKVLILP- 2828

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G   L I   + ED+G YT VA N AGE  L   + V
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 74/293 (25%), Positives = 118/293 (40%), Gaps = 46/293 (15%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   + WY +G+ L+      + ++ G  TL + +    D+G YTC A N  GE      
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGEDELDFD 2759

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            V            Q P   + L +I N+ D             TGR  E     KD++ I
Sbjct: 2760 V----------NIQVPPSFQKLWEIGNMLD-------------TGRNGEA----KDVI-I 2791

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +     + E +  P       + W+ +G  + +S ++  +   G  VL+I   K  D+G 
Sbjct: 2792 NNPISLYCETNAAPPP----TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGR 2845

Query: 3121 YSCRATNKWGQ--AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            Y+C A N+ G+   +  V++      KG        +  +      +SA  EC  +    
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLV----NKSALIEC--LSSGS 2899

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P  +  W  +GQP+      K +S+    +L I  TQ  D G YVC A N  G
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAG 2950



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 66/168 (39%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 4012 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4069

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 4070 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 4121

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L IA+ Q  D+G Y C A N  G   T   +  +
Sbjct: 4122 SIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 3236 YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 3287

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 3288 ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 4431

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG P+T+S ++  I   G V L I   + EDAG YT  AVN+ GE      
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVL-ILPGGRV-LQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862

Query: 860  IRVAARSTVT-ADLGIPEQ 877
            +RV     +  A+  +PE+
Sbjct: 2863 VRVLVPPIIKGANSDLPEE 2881



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   N   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 4404

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 4405 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 1311

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 1312 PGISILEDG-TLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            ++   EC++  +  P   V W  +G PL+ K +   I D G++ +    ++  D+G Y+C
Sbjct: 2308 KSISLECEVQGIPPPT--VTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSDTGRYVC 2363

Query: 4049 RATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
             A N+ GM + K  +     P I+ + + P+++  +EK
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 4194 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 4250 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 4300

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V     I        P      P N  
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWI 4360

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 4361 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 4417

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 2104 PNIMGEEQN 2112



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 18/164 (10%)

Query: 3079 SMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            S  + W+ +G+ +++   +  + A G   L+I   + +D+G Y+C A+N  G+ E+   +
Sbjct: 2703 SASLSWYKDGQPLKSDDHVN-IAANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV--PVD-------DPDMKIEWYHNG 3189
                    QK      I N+  L  G++   +  ++  P+         P   + WY +G
Sbjct: 2761 NIQVPPSFQK---LWEIGNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG 2815

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+  S ++  +   G  VL I   +  D+G Y C A N+ GED
Sbjct: 2816 HPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 3255 DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 3312

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            D+G YTC ATN  GE      L V     +     +    EK+  L DTS
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTI---RGNKDEAEKLMTLVDTS 3359



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  +  N     GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 4402

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  N   I  SHR R   + G + ++    K  D+G Y C A+N  G  + 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQ 692

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            +  L  ++  K         +Q+   +  G     EC    +  P +K  W+     +R 
Sbjct: 693  NSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGIPPPQVK--WFKGDLELRP 744

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLE 3250
            ST +  + D    +L I  TQ+ D+G+Y C A N+ G    + T++  G   V+++
Sbjct: 745  STFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD-VGSPPVFIQ 797



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 1170 PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 1268

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 1269 ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 1308

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 1309 GREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 1368 TNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 4078 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 4131

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 15/197 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP    V  ++  ++ G+ A     +I   D ++   W  N + +  +   R +  
Sbjct: 515  DVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLT--WQRNDRDVRLAEPAR-IRT 570

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               + LE+   K  D+G Y C  +++ G +  SV L        Q+P   T +   +   
Sbjct: 571  LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV------QEPPKVTVMPKNQSFT 624

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G      C+      P  KI W  N   +  S R +  SD    + + A     D+G Y
Sbjct: 625  GGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAA---PKDAGIY 679

Query: 3223 VCRAYNKYGEDFTRATI 3239
             C A N  G D   +T+
Sbjct: 680  GCLASNSAGTDKQNSTL 696



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PP    +P   +   G      C  TG+PKP++ W +N   IV   RY++T DG
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 4489 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 4544

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 4545 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGK 875



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 756  LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 809

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 810  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 870  ENQFGKIQSETTVTVTG 886



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 789  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 849  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 1371 SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDA 1426

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST-QNEAG--LEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +   NE    L +   LE + K      + 
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 1486

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 1487 WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C        A+T    G  I+ S +++Y++      
Sbjct: 1546 PSIKGGNVTTDI-SVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 1604

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 1605 IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++ +    + G   L +      D G Y C A +  GE
Sbjct: 1664 KAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV      +L++      D+G YSC+A N  G ++  
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVN--NGKILKLFRATPEDAGRYSCKAINIAGTSQKY 1443

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +           T+  N   +   +    EC V     PD  I W+ +G+P+   
Sbjct: 1444 FNIDVL----VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLG 1497

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 1498 DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +    G  I  E  ++ +  PT  + W+K+G  +   ++   I   G+I L + ++++ D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSD 2357

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
            +G Y C AV+  G+ + K  L V    +I    + PE +  +++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 35/210 (16%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++++  N     E     +  P   + W ++G P+++ + +    + G+  L +K    
Sbjct: 2682 KEVKIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQI 2737

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G YTC A N  GE      + +Q   S Q        L +I  + D+ R    +DV 
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ-------KLWEIGNMLDTGRNGEAKDVI 2790

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +            N P  L         C     P P +   WY +G  L S  +     
Sbjct: 2791 I------------NNPISL--------YCETNAAPPPTL--TWYKDGHPLTSSDKVLILP 2828

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
              G   L I     ED+G YTC A+N  G+
Sbjct: 2829 --GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 57/266 (21%), Positives = 102/266 (38%), Gaps = 11/266 (4%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            L GNP P   W +  A L++    ++R      D SL I+++   D GEYTC A N  G 
Sbjct: 914  LAGNPIPERRWIKNSAMLLQNPYITVR-----SDGSLHIERVQLQDGGEYTCVASNVAGT 968

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               +  +                    +  T+  KA G    +   S++ + ++ ++   
Sbjct: 969  NNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF 1028

Query: 215  HSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
             +  D    V +       E     + T  Y  +  VQ++  +   +          KP 
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYA-KRKVQLTVYVRPRVFGDQRGLSQDKPV 1087

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSD 332
               +  G +     ++   P P +TW K  Q +   S +H  + + +   +++  T+ SD
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSD 1144

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESP 358
            SG Y  +A N  G +  +  L V  P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVP 1170



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 3652 VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 3710 NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 3759

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 3760 YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 3801



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 3952

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 3996



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +G  +  S+ +R +   G  +L ++ T   D+G Y+C   N  G+      L  +
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P        +E +K  +      T     +P  +I W+ +GQP++       +
Sbjct: 2476 ------VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII 2529

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S   F  L I   Q   +G Y C A +  G      ++N +
Sbjct: 2530 SGGRF--LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2568



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  EC+   V      + W+KNG+ +T       + D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHL 3145



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 3299

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+  L 
Sbjct: 3300 NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTLV 3356

Query: 1960 DDS 1962
            D S
Sbjct: 3357 DTS 3359



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 4252 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 4306

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 4307 VN--GHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     S+ +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 4400

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     ED+G YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1385 CQATNQLGEAVTSCALRVIAKKDLILE 1411
            C ATN+ G    S +L + +   + LE
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 4364 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 4419 CVATNEAGVVERSMSLTLQS 4438



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    + KN  F  G          G P P ++WT     +V  ++Y M     T D +
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM-----TSDGT 665

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L IK   P D G Y C A N  G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAG 688



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I +  G     E  ++ I   T  V W+KDG P+  +  +    + G++ L +K++ V 
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI-LQLKNIHVS 2356

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            D G Y C A N  G      +L++     II   + P  +  ++
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G  +L I  V   DAGHYTC A N  G ++TS  LT+
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 1252 TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 1305

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 1306 ELTGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPII 1392



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 3676

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++ N    D+ +YT +A N  G       L V  P
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 3712



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 4429 ERSMSLTLQSPPIITLE 4445



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 20/170 (11%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDI---------IDESVTIKPRFVTRPKSIE 1454
            AK   IL+  H   L+ I ++ DT RY    +          D SV   P  +   +S E
Sbjct: 2336 AKGVEILDEGHILQLKNI-HVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE 2394

Query: 1455 N--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            N  V+E   V   C+   +   +  + WFK+G PV++ +  R +   G   L ++    E
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPS--ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTME 2450

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            D+G YTC   N  G +     L+      IV     E  LE ++V E +S
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLVPPHIV----GENTLEDVKVKEKQS 2496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632  RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 3429 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 3485

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
              G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 3486 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 3518

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 3519 FILKVLEPPHINGSEEHE 3536



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 3605 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 3655

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 3656 LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 3700



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 3766

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 3767 F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 12/174 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C ATN  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 1188

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 1189 DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 1244

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P
Sbjct: 1245 NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKP 1296



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 1579 ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 1635

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +  I+  
Sbjct: 1636 YVPPMIEGNLATPLN--KQVVIAHSLTLECKA--AGNPSPILTWLKDGVPVKANDNIRI- 1690

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 1691 -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG PV  S+ +      G   L +   T+ DAG YTC   NA G+      L+++
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 1003 TKKDIIAES 1011
                I+ E+
Sbjct: 2476 VPPHIVGEN 2484



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 3257 SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++  L D S
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTLVDTS 3359



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 1216

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 1217 HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 1256



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T   ++ S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 1496

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 1497 GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I V  G  +  +C V+ +  PT  + W  +G P      V  L++ G I L +  I+  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GHI-LQLKNIHVSD 2357

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
             G Y C A N  G       ++  A   I+   + P+ +S
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS 2397



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 3261 GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 3319 CVATNPAG 3326



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 4131

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 4132 --SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P+ +    N     G+ V + C     G    ++ W  N   I   HR+R   +
Sbjct: 606  LTVQEPPKVTVMPKNQSFTGGSEVSIMC--SATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI-AKKDLILESQHPSGLEKIQY 1423
                 L + +  P+D+G+Y C A+N  G    +  LR I A K ++++S+    L  I  
Sbjct: 664  G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITV 720

Query: 1424 LE 1425
            +E
Sbjct: 721  ME 722



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 714 ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 769

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 770 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 826

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 881

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 938

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAG 967



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 1351 YNLKVHVPPVIKDKEQ-------VTNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 1400

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 1401 VTESSTIQTVNN--GKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+  IR + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 1725 YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLIDE 1777

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 1778 RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 1813



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEK 2092

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 2093 QRDIDLRV 2100



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 633  VYPPPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V+ PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTN--TLIVP 3015

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            G  +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   V  EC  E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 3071 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 3127 QYVCRAINVAGRD 3139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LEC    +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 4433 SLTLQS 4438



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 860  IRVAARSTVTADLGIPEQRRYI 881
            + V     +  +L  P  ++ +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVV 1654



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ + + +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 2003

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 2004 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 2053

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +   Q  D+G Y C A N  GE
Sbjct: 2054 SFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVNAAGE 2091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G+ +  EC+++ +      V W K+G P+ I  +   I D G++ L + ++   D+G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSDTG 2359

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             Y C AVN+ G  +    L+  +   I+    N    E I V+E  S
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSII---GNHRSPENISVVEKNS 2403



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G++   E ++  +  PT  V W KDG P+  +  +  I + G++ L + ++   D G Y 
Sbjct: 2307 GKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGV-EILDEGHI-LQLKNIHVSDTGRYV 2362

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
              AVN  G       + V A  ++  +   PE    +EK
Sbjct: 2363 CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   EC     P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 3073 EGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 3302 STLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)

Query: 3047 PPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP  +   K+ ++ + +      EA  +P  D    I W  +G+ I  S R R V + G 
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPD----ITWHKDGRAIVESIRQR-VLSSGS 4132

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LK 3162
              L+I   +  D+G Y+C A N  G +  S KL     +    PR    I++ EG   + 
Sbjct: 4133 --LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL-----TVHVPPR----IRSTEGHYTVN 4181

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +   A   C    +  P   I W  +   + +     T   +G ++L+    +  DSG Y
Sbjct: 4182 ENSQAILPCVADGIPTP--AINWKKDNVLLANLLGKYTAEPYGELILENVVLE--DSGFY 4237

Query: 3223 VCRAYNKYGED 3233
             C A N  GED
Sbjct: 4238 TCVANNAAGED 4248



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 788  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 900

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 901  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 956

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 957  EYTCVASNVAG 967



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 1351 YNLKVHVPP 1359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 84/375 (22%), Positives = 143/375 (38%), Gaps = 32/375 (8%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            +NI V E   V   C  E  G P   I WF +G P +  + V  L+  G   L +     
Sbjct: 2394 ENISVVEKNSVSLTC--EASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTM 2449

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+YTC   N  G       ++      IV E+ L      EK        ++  P  
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E       + + + ++H +    G RF  ++   + P      Y      P+GH+ R+  
Sbjct: 2510 EITWHKDGQPLQEDEAHHI--ISGGRF-LQITNVQVP--HTGRYTCLASSPAGHKSRSFS 2564

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVND------FGEDFTKATISCKKLPDIILQNQVPR- 3935
               FVS  I  V ++ + E +   +N           +  ATI+  K    +  N+  R 
Sbjct: 2565 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI 2624

Query: 3936 --GMKRSEALTQMEATIKKYTSEVYLTEDDL---YDVDKKQPP------RFVTQIQSQTS 3984
              G +  + L   E    +Y+        ++   Y+V    PP       +   +  +  
Sbjct: 2625 LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEV 2684

Query: 3985 LVEMETT-KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
             +++  T   EC+   +  P+  + W+ +G+PL   +    I   G+  +        D+
Sbjct: 2685 KIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVN-IAANGH-TLQIKEAQISDT 2740

Query: 4044 GEYLCRATNLYGMDE 4058
            G Y C A+N+ G DE
Sbjct: 2741 GRYTCVASNIAGEDE 2755



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 4429 ERSMSLTLQS 4438



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 87/402 (21%), Positives = 156/402 (38%), Gaps = 41/402 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 791  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 966

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 967  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 1023

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDQRGLS 1082

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 1137

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +    DSG+Y C A N+ G    + +L       I R  ++
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 1544 IPPSIKGGNVTTDI----SVLINSLIKLECETRGLPMP--AITWYKDGQPIMSSSQALYI 1597

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 1598 -DKG-QYLHIPRAQVSDSATYTCHVANVAG 1625



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 2063

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 2064 GGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V  GK+   EC+V+ +  P   + +  +G  L  A    I  D G++ L +++    D G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTG 2359

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             Y   A+N  G       ++V A  SII   + PE +  + +   +   +   IP P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 3261 GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDT--QNEQAIEQIQLLEDAA 1295
              A N  G        R+   +  VT T   N+   E++  L D +
Sbjct: 3319 CVATNPAGEED-----RIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 3359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S      G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 4399

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL+L+S   +   +   +  S        V + V + P+ +T +      + G      C
Sbjct: 575  SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMC 633

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P  ++ W  N   +   HRYR ++D     L I     +D+G Y C A N+ G
Sbjct: 634  SATGYPKP--KIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 1927 QAVSSIRLN-VQSKESIIRDSQHESALEKIQYLE 1959
                +  L  +++ + ++  S+   AL  I  +E
Sbjct: 689  TDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 897  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 952

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 953  QDGGEYTCVASNVAG 967



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 1224

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
             +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 1225 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 1907

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY + + +
Sbjct: 1908 QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNRLL 1961

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1962 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1998



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +   + +D+G Y+C A N  G+ +  + L   
Sbjct: 2043 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVY 2101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 2102 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 2152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S+    VL I   Q  D+G Y C A N  G+      +N +
Sbjct: 2153 SE-NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 54/211 (25%), Positives = 82/211 (38%), Gaps = 34/211 (16%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            S K V+IK       E     +  A+L   WY + +PLKS        N G   L I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASLS--WYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSA 1702
               D+G YTC         V S IA    +    +  Q   +  +L ++ +     R+  
Sbjct: 2736 QISDTGRYTC---------VASNIA-GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
              +VI   P+           E  AA           P   + W ++G P+ +S+++  +
Sbjct: 2786 AKDVIINNPISLY-------CETNAA-----------PPPTLTWYKDGHPLTSSDKVLIL 2827

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G   L +     ED+G YTC A+NE GE
Sbjct: 2828 P--GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633  VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 3052 VYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTH-VEI 3108

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
               G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 3109 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 3154



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 3126

Query: 842  SYTVRAVNKLG 852
             Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             NL +     I          EK+  L D S
Sbjct: 3332 FNLNVYVTPTIRGNKDE---AEKLMTLVDTS 3359



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS+ I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 4403

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 4404 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 4461

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 4462 QATGEPQPTIT 4472



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 18/270 (6%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 1102 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATNIAG 1157

Query: 154  EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
                +V +                        +   A GT       S+    +   +G 
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 1216

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
             H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 1217 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 1269

Query: 272  PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
            P N+  QE    Q   F     G P+P + W  NG+ L    +  I    + T L + + 
Sbjct: 1270 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEDGTLLVIASV 1328

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               D+G Y  +A N  G       L V  P
Sbjct: 1329 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 22/283 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 1225

Query: 131  LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
            L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 188  H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                A GT        + T K  + NG + +  +       +  LL   S        Y+
Sbjct: 1286 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337

Query: 246  GESDVQI-STEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
              +  +  +TE   +L    PP I  K +  N  +          ++ G P P + W+K+
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 1398 NVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ I+     + +     +V  I   + +++G Y C A N  G    
Sbjct: 1759 TGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKK 1816

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 1817 EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 1865

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 1866 PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 724  AVLHVTPRATIE 735
              LHV    ++E
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQIS--DTGRYTCVAVNAAGEKQR 2094

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 2095 DIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P+++I++   S   EC +  +   +  V W  +G PL+    V+ +++ G  IL++  ++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GH-ILQLKNIH 2354

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
              D G Y C A N  G       L V     II   + P +
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            +L++     +D+G Y C A N  G  +    L      S     R   +I  +E  K+  
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE--KNSV 2404

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   E + +P+      I W+ +G P+  S  ++ +S  G  +L +  T   D+G+Y C 
Sbjct: 2405 SLTCEASGIPLPS----ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCV 2458

Query: 3226 AYNKYGED 3233
              N  GE+
Sbjct: 2459 VRNAAGEE 2466



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 34/215 (15%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+    +   EC  E Y  P+  + WY +G+ L+S      + + G   L I      D+
Sbjct: 2685 KIKVNNTLTLEC--EAYAIPSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDT 2740

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G YTC A N  G+      +N+Q   S          L +I  + D  R   A       
Sbjct: 2741 GRYTCVASNIAGEDELDFDVNIQVPPSF-------QKLWEIGNMLDTGRNGEA------- 2786

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
                         +V   +P+ L         PT+   WY +G P+      K     G 
Sbjct: 2787 ------------KDVIINNPISLYCETNAAPPPTL--TWYKDGHPLTSSD--KVLILPGG 2830

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              L I  A  ED G Y C A N  GE      V+V
Sbjct: 2831 RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 3122

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 3123 SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 3170

Query: 3548 LTPEAESGNPP 3558
            LT +A +G PP
Sbjct: 3171 LTCDA-TGIPP 3180



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 785  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 843

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 844  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 1006 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 1063

Query: 724  AVL--HVTPR 731
              L  +V PR
Sbjct: 1064 VQLTVYVRPR 1073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTV-NNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 860  IRVAARSTV 868
            I V    T+
Sbjct: 1446 IDVLVPPTI 1454



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+  +   +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 1510

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1952 ITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 2010 VAPSISGSN 2018



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            +++  + V   P      + PT++  + G+S   EC ++  P P   V W  +G  L   
Sbjct: 2279 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKA 2336

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                  ++     L +  ++  D+G Y C A+N  G       L+V +  SII    H S
Sbjct: 2337 KGVEILDEGHI--LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII--GNHRS 2392

Query: 1951 ALEKIQYLEDDS 1962
              E I  +E +S
Sbjct: 2393 P-ENISVVEKNS 2403



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +C    V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 3124

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 3125 TGQYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 3126

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626  PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 3661

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 3662 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 3529 EGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS 3588
            EG  + IA     +G   T    +E   PP     P+++ ++    A   C +I   D +
Sbjct: 494  EGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550

Query: 3589 MRVEWFHNGKP--LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            +   W  N +   L   +R++T+ +     LE+  V   DAG Y C  ++  G +  S  
Sbjct: 551  LT--WQRNDRDVRLAEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVF 605

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTE 3670
            L V+    + + P+  S F  G+E
Sbjct: 606  LTVQEPPKVTVMPKNQS-FTGGSE 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PPK     K+ +      V   C       PK +I W  N   +   HRYR   D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGY--PKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              +L I     +D+G Y C A N  G D   +T+   + P +++
Sbjct: 664  -GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 916 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 972

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 973 TSVVVHVLP--TIQHGQQILSTIEGI 996



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P+++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 1446 IDVLVPPTIIG-----TNFPNEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 1496

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 1497 GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 1405 KKDLILESQ-HPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            +K +I ++Q   +GL +         +KK    + +V + P   +   S   V++ + V 
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVA 1845

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
             +C    +   N  + W K+ QPV        I   G V L I   + ED+G YTC A N
Sbjct: 1846 LQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902

Query: 1524 LVGTDEVSCRL 1534
              G  +   +L
Sbjct: 1903 AAGETQQHIQL 1913



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S P   + W+KDG P+ ++  I  +   G  +L I++ + ++AG Y+  A N+ GE I  
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658

Query: 858  ASIRV 862
              ++V
Sbjct: 2659 YEVKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+G  L +   ++     G  TL I + + D++G Y+C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2732 IKI 2734
            +K+
Sbjct: 2661 VKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +C    V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 860  IRVAARSTV 868
            + V    T+
Sbjct: 3334 LNVYVTPTI 3342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 3829 GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 3886

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 3887 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 3945

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 3946 ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 3998

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 4056

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQVP 4078



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 4126

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 4127 VLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 791  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 850  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 994  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 1003 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 1058

Query: 154  EA----ICSVYIQP 163
             A      +VY++P
Sbjct: 1059 YAKRKVQLTVYVRP 1072



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/179 (21%), Positives = 72/179 (40%), Gaps = 7/179 (3%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W   G  +      R     G   L+I   + +D+  YSC A+N  G A+    L+    
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY-- 2287

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             +       +H   I  +  G+S   EC V  +  P   + W  +G P+  +  ++ + D
Sbjct: 2288 IRPTITNSGSHPTEII-VTRGKSISLECEVQGIPPP--TVTWMKDGHPLIKAKGVE-ILD 2343

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
             G  +L +      D+G YVC A N  G    +  ++ +    +      P++++ + +
Sbjct: 2344 EGH-ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E  + P  TI WF +G  + +    R     G   L IL    +++G Y C ATN+ GE 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 2194 VNTCTLKV 2201
            +    +KV
Sbjct: 2656 IKHYEVKV 2663



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIH--FETRIE----PVGDPTMKIEWLKNGQSI 679
            P GEEDR++    ++ P       E  K+    +T I       G P  +I WLKNG  +
Sbjct: 3324 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 3383

Query: 680  EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
              SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 3384 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 3421



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 3728 KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 3784 MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 3795

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 3796 IDLQVHVPP 3804



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 4151 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 4204

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 4205 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 1253 EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 1304

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 1305 RELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 1346



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 1259 QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 1312

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 1313 GISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 1354



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 653  KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            K+  ETR    G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC 
Sbjct: 1566 KLECETR----GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCH 1619

Query: 713  AVSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
              +  G AE    + V     IE     P   Q +
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 1654



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284  QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
            + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 1623

Query: 344  NGCIVTSGYLAVESP 358
             G    S ++ V  P
Sbjct: 1624 AGTAEKSFHVDVYVP 1638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+ + +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 2003

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 2004 YSLQVHVAP 2012



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKDG P+     ++   N     L I+   V D G YTC A N  G+   + N+ I
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ WY +G+ + S + +    + G+  L I   +  D+G YT VA N AGE +L   + +
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            +   S       + L+E          +  M       ++K V +   +NP        I
Sbjct: 2763 QVPPSF------QKLWE----------IGNMLDTGRNGEAKDVII---NNP--------I 2795

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C       PT+   W+ +G  +T  S  K     G   L I  A   D G YT  AV
Sbjct: 2796 SLYCETNAAPPPTL--TWYKDGHPLT--SSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851

Query: 1256 NHLGSAHTSAIVRVI 1270
            N  G       VRV+
Sbjct: 2852 NEAGEDSLQYDVRVL 2866



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 3253 PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 3309 ALTSDTGKYTCVATNPAGE 3327



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 3469 WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 3526

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 3527 PHINGSEEH 3535



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 3523 VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 3580

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 3581 GEVLRISTAQVEDTGRYTCLASSPAGD 3607



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 3767

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 4197 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254

Query: 1134 TV 1135
            TV
Sbjct: 4255 TV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 4268 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 4321

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G     G
Sbjct: 4322 DSGTYVCTAENSVGFVKAIG 4341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 4451 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 4506

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 4507 FECVARNLMG 4516



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  KI W  N+  +    RY+ T D +   L I +   +D+GIY C A+NS G+   + +
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 2863 LR 2864
            LR
Sbjct: 696  LR 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 994  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 1106

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 1107 PPPIITWAK 1115



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 265  PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP I     P    +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 1509

Query: 323  LRVRNTQKSDSGHYTLLAENPNG 345
            L ++N +++D G Y     N  G
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 7/149 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            SH   I+   G +I  EC V+    PT  + W  +  PL      +   D  ++ L + +
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKN 2352

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
             +  D+G Y C A N  G       L      +I  + + P+    +  VE+   +   +
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE---NISVVEKNSVSLTCE 2409

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEG 2926
                 +P   + K  W + ++   +++ G
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSG 2438



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   + W+ +G P++     +     G   L IL A  ++ G Y C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2067 VKV 2069
            VKV
Sbjct: 2661 VKV 2663



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 3124

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 3242 QVPPSVAGAEI 3252



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 3439 SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 3494

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 3535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 4100 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSS 4157

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 4158 STSTKLTVHVPPR--IRSTEGH 4177



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 4194 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 4251

Query: 997  ANLTI 1001
             +LT+
Sbjct: 4252 VSLTV 4256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 6/142 (4%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
            Q  + +    L I++    DEG Y+C+A +SAG         V++P     +P      +
Sbjct: 474  QYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVP-----NN 528

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V  G+ A     I S +   + W R    +    +   I    N  L + +    D G
Sbjct: 529  VTVTPGERAVLTCLIISAVDYNLTWQRNDRDV-RLAEPARIRTLANLSLELKSVKFNDAG 587

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C  ++  G    S  L V+
Sbjct: 588  EYHCMVSSEGGSSAASVFLTVQ 609



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK ++ W  N + I  S+R     D     L +K   P+D+G Y C A N  G    +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 1798 STL-FVQSKASLQLESQHESALQKIQQLE 1825
            STL ++++   + ++S+   AL  I  +E
Sbjct: 694  STLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 775  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449

Query: 1003 TKKDII 1008
                II
Sbjct: 1450 VPPTII 1455



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 3833 ITQIKSHTVE----ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            IT   SH  E      + +  EC V+    P   + W ++G  L        + D G + 
Sbjct: 2292 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI- 2347

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGM 3937
            L +  ++  D+G Y+C AVN  G    K  +S    P II  ++ P  +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2396



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            P   + WF +G  L      R     G   L IL   E+N+G Y CVATN+ G
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            DV    P+   C       PT+   W+ +G P  +  +V  L   G   L I      DA
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDA 2843

Query: 3766 GEYTCRATNKWG 3777
            G YTC A N+ G
Sbjct: 2844 GRYTCVAVNEAG 2855



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL TL D+ +
Sbjct: 3334 L------NVYVTPTI-RGNKDEAEKLMTLVDTSI 3360



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 3581

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 3685

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 3686 -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3744

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 3745 TWRKDGAVLAGNHARYSILENGFLHI---QSAH 3774



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L IA V+  D+G YT +A N AG +  S  +TV 
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAI 4187



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP + Q P N  +  G  A     +       +TW +N + +  +    I T  N  +L 
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLE 577

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
           +++ + +D+G Y  +  +  G    S +L V+ P +  V  +   +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSF 623



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 790  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 847  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 897  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 951

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 952  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 1236

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQE 1260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFET-RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            VY PP     L +    +    H  T   +  G+P+  + WLK+G  ++A+         
Sbjct: 1635 VYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR--IEA 1692

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
            G   L+++S    D G+Y C A S  G  E K  + V     IE
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 1736



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 2039 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDID 2097

Query: 860  IRV 862
            +RV
Sbjct: 2098 LRV 2100



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 2099 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 2156

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              + ++     +QD+G YTC A +  G  E
Sbjct: 2157 SVLKIE--DAQVQDTGRYTCEATNVAGKTE 2184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R+  NI  VE  +V L C     G     + WF +G P+   +  R         L L+ 
Sbjct: 2391 RSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQ 2446

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
               ED+G YTC   N  GE      L V+    ++ E+
Sbjct: 2447 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN 2484



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W+KDG P++ S+ +  I + G + L +M    EDAG YT    N  GE
Sbjct: 2414 PLPSITWFKDGWPVSLSNSV-RILSGGRM-LRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P+  + WYKDG+P+ +   +    N G+ +L I   +  D G YT  A N  GE
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGE 2753



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG P+ +S ++      G   L I    V DAG YTC A N  G+ +   ++ ++
Sbjct: 2811 WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+ N++EG     EC    +  P +T  W+ NG+ I          D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPVIT--WYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2177 EDSGTYMCKATNKLG 2191
             D+G Y+C+A N  G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 3147 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
               L +      DSG YTC A +  G A+
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 3449 KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 3504

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3536



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 3769

Query: 325  VRNTQKSDSGHYTLLAENPNG 345
            +++   +D+G Y  +A N  G
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAG 3790



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 4106 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162

Query: 860  IRV 862
            + V
Sbjct: 4163 LTV 4165



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 4419 CVATNEAGVVERS 4431



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 4427 VVERSMSL 4434



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 4433 SLTLQSPPIITLEPVE 4448



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKI 876



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + W KD R +  S+ +T F N G + + I+S  + DAG Y C A N+ G
Sbjct: 1952 ITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +  A  +DTG YT  A
Sbjct: 2029 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVA 2085

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 3261 GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTS 4160

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 4161 TKLTVHVPPRIRSTEGHYTVNENSQAI 4187



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP--FATGSR 3743
            T  D    PP   +++ +N+ V  G      C +    D    + W  N R    A  +R
Sbjct: 512  TFFDVSEPPP--VIQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPAR 567

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            + TL +   ++L++  +   DAGEY C  +++ GS+  +  +T
Sbjct: 568  IRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 700  EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 754

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 755  GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 798



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 1236

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTV 1264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++ +LL SG    T  + G + +DI      
Sbjct: 1929 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNRLL-SGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1985 DAGIYKCVAINSAG 1998



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 1176 KPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +P      S+P    V+ GK+I LEC ++ +  PT  V W  +G  +      +   +  
Sbjct: 2289 RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGH 2346

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
             + L  IH   +DTG Y   AVN  G       + V     I+ + ++ + I  ++
Sbjct: 2347 ILQLKNIHV--SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+ E QS    C +   P P   + W+ +G+ LQ    +   +   F  L I  V    +
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPE--ITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545

Query: 1915 GEYTCKAINNLGQAVSSIRLNV 1936
            G YTC A +  G    S  LNV
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNV 2567



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P D+ +  NS     C       ++  + WF +G PL +   ++ +   G   L+I    
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPAT--ITWFKDGTPLESNRNIRILP--GGRTLQILNAQ 2637

Query: 3624 QRDAGLYTCKATNRHGE 3640
            + +AG Y+C ATN  GE
Sbjct: 2638 EDNAGRYSCVATNEAGE 2654



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 51/193 (26%), Positives = 78/193 (40%), Gaps = 41/193 (21%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            P+  + W+ +G+P  +   V+   + G   L I      D G YTC A+N          
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASN---------- 2749

Query: 3785 ITCSAKRDIVLESQLPQGMSGEKIKE----LERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            I    + D  +  Q+P   S +K+ E    L+ GR  +A  ++ I++ P           
Sbjct: 2750 IAGEDELDFDVNIQVPP--SFQKLWEIGNMLDTGRNGEA--KDVIINNP----------- 2794

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
                  +   C       P L   WY++G  L S  +   +   G V L I     ED+G
Sbjct: 2795 ------ISLYCETNAAPPPTLT--WYKDGHPLTSSDKV-LILPGGRV-LQIPRAKVEDAG 2844

Query: 3901 EYICRAVNDFGED 3913
             Y C AVN+ GED
Sbjct: 2845 RYTCVAVNEAGED 2857



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+I++   S + E    P       + W+ +G PL +  +V  +   G  +L+I      
Sbjct: 2788 DVIINNPISLYCETNAAP----PPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVE 2841

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            DAG YTC A N  GE ++   ++V
Sbjct: 2842 DAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T+  T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 3354 TLVDTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 3409

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3519

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 3520 ILKV-------LEPPHINGSEEHEEI 3538



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 4438 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4494

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 4495 YIADAQ---KEDTSEFECVARNLMGS 4517



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P+     KN   T G  V +  + T    P  ++ W  N   +   HR++ T D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG- 664

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
               L I  A  +D G Y C A+N+ G     S+++
Sbjct: 665  --TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI W  N   +    R+++TSD    TL + +   +D+GIY C A N  G    +ST
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 3001 V 3001
            +
Sbjct: 696  L 696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 756

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 757  -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 794  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 854  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICV 1339

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 1340 AVNEAGTTERKYNLKV 1355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAG 1345



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   P  + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNF---PNEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 1493

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 1471 VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 1527

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 1528 SNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915

Query: 1136 ETRSSID 1142
                S++
Sbjct: 1916 HEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G  + LE  +  +  PT  V W  +G P+ +    +   D G++ L +   +  DTG
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTG 2359

Query: 2049 TYMCKATNAVG 2059
             Y+C A N  G
Sbjct: 2360 RYVCVAVNVAG 2370



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 8/144 (5%)

Query: 3962 DDLYDVDKKQPPRFVTQIQS--QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            D  YD+    PP  +   +S    S+VE  +    C+ +  G P   + WF +G P+   
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLS 2430

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
            N    +   G   +       ED+G+Y C   N  G +     +     P IV ++ L +
Sbjct: 2431 NSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-E 2487

Query: 4080 HMKSIEKIREMEASWQVTPEQVVE 4103
             +K  EK + +  + +VT   V E
Sbjct: 2488 DVKVKEK-QSVTLTCEVTGNPVPE 2510



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + W+ +G  L+S    R     G   L IL    +++G Y+C A N  G+ 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 1929 VSSIRLNV 1936
            +    + V
Sbjct: 2656 IKHYEVKV 2663



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV 3622
            +P ++ +  N++   EC    +  +S+   W+ +G+PL +   V    + G   L+I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 3623 YQRDAGLYTCKATNRHGE 3640
               D G YTC A+N  GE
Sbjct: 2736 QISDTGRYTCVASNIAGE 2753



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDL 1509
            PK ++  +    +  EC+   +  ++L   W+K+GQP+        I   G+  L I + 
Sbjct: 2681 PKEVKIKVNNT-LTLECEAYAIPSASLS--WYKDGQPLKSDDHVN-IAANGHT-LQIKEA 2735

Query: 1510 IAEDSGIYTCRAVNLVGTDEV 1530
               D+G YTC A N+ G DE+
Sbjct: 2736 QISDTGRYTCVASNIAGEDEL 2756



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/120 (30%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            EDS +Y  R  V   +  A    + L     +   +SA  EC     P P  R  W  +G
Sbjct: 2856 EDSLQYDVRVLVPPIIKGAN---SDLPEEVTVLVNKSALIECLSSGSPAP--RNSWQKDG 2910

Query: 1885 K-VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            + +L+  H    SN      L IL     D G Y C A N  G A     LNV    S+I
Sbjct: 2911 QPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2967



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 2986 CEVSGFPPPDL--SWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 3041

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 3042 GESKKKFSLTVYVPPS-IKDHDSES 3065



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 8/151 (5%)

Query: 2194 VNTCTLKVAGHRNI-ILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV---TELR 2249
            +NT TL V G R + I+  +  +G E       Q   ++ +       PP      +E  
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESL 3066

Query: 2250 GTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
               +V EG +   EC+   V  P   I +Y NG+ +  +    I  D G + L I+    
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
             D G+Y  +AIN  G       + V    SI
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 3447 VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 3502

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 3503 KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 3674

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 3675 RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 3722



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 3979

Query: 724  AVLHV 728
              LHV
Sbjct: 3980 VTLHV 3984



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 14/133 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 4217 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 4268

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 4269 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 4322

Query: 3219 SGEYVCRAYNKYG 3231
            SG YVC A N  G
Sbjct: 4323 SGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W +N + +    R+R T D    TL I +    DAG+Y C A N AG
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V    PV  +C+    G+P   I W+ + R   +GS   T  + G I +DI+     
Sbjct: 1929 NETVLVSNPVQLECKA--AGNPVPVITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3764 DAGEYTCRATNKWGS 3778
            DAG Y C A N  G+
Sbjct: 1985 DAGIYKCVAINSAGA 1999



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 3826 VSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNEQ--PIKLNTNTLIVP 3015

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            G  +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN+ GE+   
Sbjct: 2990 GFPPPDLSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 3108 ILADGQMLH 3116



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 2996 LSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 1003 TKKDI 1007
                I
Sbjct: 3054 VPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 724  AVLHVTPRATIERTSQHPETL 744
              L+V    TI       E L
Sbjct: 3332 FNLNVYVTPTIRGNKDEAEKL 3352



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 1791 LGE 1793
             G+
Sbjct: 3605 AGD 3607



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 3712 PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 3768

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 3769 HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 3887

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 3888 TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 3936

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 3937 LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 3985



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 3952

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 3993



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 4260 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 4312

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  +T +   ++   G      C       P +   W  N   I   HRYR T D   
Sbjct: 609  QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDMFIVGSHRYRMTSD--- 663

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
              L I     +D+G Y C A+N  G      TL+
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 1273 TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVT 1329

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 1330 PYDNGEYICVAVNEAGTTERKYNLKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 3510 MKV 3512
            +KV
Sbjct: 1353 LKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAG 1438



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 1671 SKKSI 1675
               S+
Sbjct: 1917 EPPSL 1921



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1946 GNPVPVITWYKDN-RLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L  +T +EG  I      E  G P   + W K G  +   S        G   L +    
Sbjct: 2203 LTQLTVIEGNLISL--LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE 2260

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
              D+  Y+C A +  G A+ +  L V  R TI  +  HP
Sbjct: 2261 KSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHP 2299



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG  + L  +      PNL   W K G  + T +  +     G   L I+     D+ 
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLI--WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2265

Query: 2714 IYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            +Y+C A+N+ G A    ++++  R  +     HP  +
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W+++G P+  +  +  + D G++ L +K ++  D+G Y C A+N  G     
Sbjct: 2318 GIPPPTVTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2375

Query: 1798 STLFVQSKASL 1808
              L V +  S+
Sbjct: 2376 YDLSVHAPPSI 2386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P   + W ++G P+E++  +  +   G   L +     +++G Y+C A NE GE +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 2963 PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GG 3017

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 3430

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 3431 FAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 3791



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 3744 ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3801

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 3802 VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 3852

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 3853 YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 4260 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 4312

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 945  WLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            W ++ R V  +  +RI T  N   ++L +KSV  +DAG Y C   +  G +  S  LT+ 
Sbjct: 553  WQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 1002 -VTKKDIIAESQHPGGLEKIQYLEDASRYSK 1031
               K  ++ ++Q   G  ++  +  A+ Y K
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPK 640



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    PK+ ++   G  V   C          K+ W  N   +   HR+R   D     
Sbjct: 612  PKVTVMPKN-QSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG---T 665

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L I +   +D+GIY C A N  GTD+ +  L
Sbjct: 666  LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            +T+T+   +   + +  + A    Q  + + V   P+  R   +++   G  V + C  Q
Sbjct: 1137 ITETRTSDSGMYLCVATNIAGNVTQAVK-LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G     + W   G  +        +     +++D  +  P D+G+YTC ATN  G   
Sbjct: 1196 --GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT--PSDAGIYTCVATNIAGTDE 1251

Query: 1396 TSCALRV 1402
            T   L V
Sbjct: 1252 TEITLHV 1258



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            +L C +E  G P+  + W+ +   VT  S  +T  + G + L +  AT  D G Y+ +A+
Sbjct: 1379 NLFCEVE--GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAI 1434

Query: 1256 NHLGSAHTSAIVRVIERSDIV-TDTQNEQAI 1285
            N  G++     + V+    I+ T+  NE ++
Sbjct: 1435 NIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 1465



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   + WYKD R ++ S+ +T   N G + ++I   +  DAG Y   A+N  G      
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 859  SIRVAARSTVT 869
            S++V    +++
Sbjct: 2005 SLQVHVAPSIS 2015



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ID  V + P  +   +++ +V+  Q V   C+ + +    L   W K+G P+ +      
Sbjct: 2096 IDLRVYVPPNIMGEEQNV-SVLISQAVELLCQSDAIPPPTLT--WLKDGHPL-LKKPGLS 2151

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            I +   V L I D   +D+G YTC A N+ G  E
Sbjct: 2152 ISENRSV-LKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3694 PPRFTVE-IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP    E   +++ V E   V   C V   G+P   I W  +G+P       H ++   F
Sbjct: 2477 PPHIVGENTLEDVKVKEKQSVTLTCEV--TGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2534

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I  +     G YTC A++  G
Sbjct: 2535 --LQITNVQVPHTGRYTCLASSPAG 2557



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  + E    P+  + W+K+G  L +   +    +    TL I   +  D+G YTC A+N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASN 2749

Query: 2722 LLGE 2725
            + GE
Sbjct: 2750 IAGE 2753



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 2/72 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KDG+P+        F + G + L I +  + D G Y C A N  G A   
Sbjct: 2898 GSPAPRNSWQKDGQPLLEDDH-HKFLSNGRI-LQILNTQITDIGRYVCVAENTAGSAKKY 2955

Query: 997  ANLTIVTKKDII 1008
             NL +     +I
Sbjct: 2956 FNLNVHVPPSVI 2967



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 14/146 (9%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYVALDLLSVY 1376
            N+  V    + L C +   G     + W  N +PIK  T     P        L ++   
Sbjct: 2973 NLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTNTLIVPGGR----TLQIIRAK 3026

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              D G YTC A NQ GE+    +L V       ++      L  +   E TS      + 
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTS----VSLE 3080

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHV 1462
             ES  + P  +T  K+   + E  HV
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHV 3106



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 3073 EGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 3129 VCRAINVAG 3137



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W +N K IE+S  +      G   + I+  +  D G Y C ASN+ G+
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 3318

Query: 146  CTARNQYGE 154
            C A N  GE
Sbjct: 3319 CVATNPAGE 3327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 3357 DTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 3412

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 3413 CVASNRAGVDNKHYNLQV 3430



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 3556 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613

Query: 860  IRV 862
            +RV
Sbjct: 3614 VRV 3616



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 3728 KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 3782

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  +G+ ++   R + ++      L+I  V   DAG YTC A N  G ++ S KL V
Sbjct: 4110 ITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 4364 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 4418

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 4419 CVATNEAG 4426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPP   VP  +VT   G +      I    D    + W +N + +  +     I     +
Sbjct: 519 PPPVIQVP-NNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEP-ARIRTLANL 574

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQ 739
           SL++ S+   D+GEY C   S  G +     L V   P+ T+   +Q
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 702  PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 757

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 758  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 799



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 1007 NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 1063

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 1064 VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 1118

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 1119 LISPFSPRH 1127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 1253

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQE 1277



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +E  P P   + WY +   +      +T N+     L +     ED+G Y+CKAIN  
Sbjct: 1382 CEVEGTPSPI--IMWYKDNVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIA 1437

Query: 1926 GQAVSSIRLNVQSKESII 1943
            G +     ++V    +II
Sbjct: 1438 GTSQKYFNIDVLVPPTII 1455



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1844 PRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            P  I   N P ++S    +    EC+++  P P+  + W+ +GK L  G       D G 
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRG- 1507

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L +      D G Y C   N  G+    I+L +    SI
Sbjct: 1508 QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 1548



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+     +   + G   L+I+ A   
Sbjct: 1650 NKQVVIAHSLTLECKAA--GNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEI 1705

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 1838 VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 1894

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 1895 RYTCVATNAAGE 1906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 1912

Query: 2199 LKV 2201
            L V
Sbjct: 1913 LHV 1915



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 2001 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 2057

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 2058 GLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 2109



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V   +PV LE     +  P++   W  +G PV            G + L +  A   DTG
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLT--WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTG 2079

Query: 2049 TYMCKATNAVGE 2060
             Y C A NA GE
Sbjct: 2080 RYTCVAVNAAGE 2091



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 2034 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVN 2087

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 2088 AAGEKQRDIDLRV 2100



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  + + Q+ + L+  +  +  CQ   +  P +   W  +G PLL K   +   +   +
Sbjct: 2103 PPNIMGEEQNVSVLIS-QAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENRSVL 2159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V  +D+G Y C ATN+ G  E    +     P I
Sbjct: 2160 KIEDAQV--QDTGRYTCEATNVAGKTEKNYNVNIWVPPNI 2197



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G ++ LEC +Q +   T  V W  +G P+          E     L L +++  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSD 2357

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            +G Y C A N  G       L V A   +I   + P  +  ++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P   + W ++G P+  SN +  +   G   L +     ED+G YTC   N  GE
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P ++ +  N SA  EC  +     + R  W  +G+PLL     K +++    IL+I    
Sbjct: 2879 PEEVTVLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQ 2934

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQV 3649
              D G Y C A N  G A     L V
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNV 2960



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/71 (33%), Positives = 31/71 (43%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N   IE S+ L      G   L +      DSG YTC A N  G+A   
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 1798 STLFVQSKASL 1808
              L +Q   S+
Sbjct: 3237 YFLSIQVPPSV 3247



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 4165 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 4222

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 4223 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 4426


>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-268N14 on chromosome 1. ).
          Length = 5635

 Score =  129 bits (312), Expect = 2e-28
 Identities = 107/384 (27%), Positives = 161/384 (41%), Gaps = 35/384 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  ++ A  E    G P P   W ++  P+      +    S   IL I    + D   +
Sbjct: 2884 VLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRILQILNTQITDIGRY 2941

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGT 4540
              VAEN  G+AK   NL V           VPPS     ++N+ V     + L  +V+G 
Sbjct: 2942 VCVAENTAGSAKKYFNLNVH----------VPPSVIGPKSENLTVVVNNFISLTCEVSGF 2991

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P D+ WLKN + ++ +    I+   G  TL I+ A   D G+Y C+AIN AGE++    
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V +P       P  K  ++     E L    V EG ++   C+    P P + WYK  
Sbjct: 3050 LTVYVP-------PSIKDHDS-----ESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3097

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            ++I  S + ++   AD   L I +A   D G Y C A N AGR      L V  P   + 
Sbjct: 3098 RMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155

Query: 4721 LPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                 P R+++V     P       T    PTI WL+    I  +   ++      + L 
Sbjct: 3156 -----PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVE 4803
            I  +   D+G +TC A+   G+ +
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQ 3234



 Score =  119 bits (287), Expect = 2e-25
 Identities = 103/380 (27%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 1148

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 1149 LCVATNIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 1257 HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 1305

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   D   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 1306 EL--TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               +T   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 1364 KEQVT---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKL 1418

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 1419 FRATPEDAGRYSCKAINIAG 1438



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/371 (27%), Positives = 155/371 (41%), Gaps = 39/371 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + W R +  ++ +   +I T +  S L ++ V   D+  +  +  + GG++  S  L V+
Sbjct: 551  LTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E          PP  T+  +N + T G  V +    TG     + W  N   +    R +
Sbjct: 610  E----------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYR 659

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             +  DGT  L I  A P+D+G Y C+A NSAG                DK     +   A
Sbjct: 660  -MTSDGT--LFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEA 701

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P +++    + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+
Sbjct: 702  P-KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLK 758

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I E    D GDY CVA N AGR T    L V  P      PA     D+ +  G      
Sbjct: 759  IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLP 813

Query: 4742 TQITSKIKPTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              +    +PTI+W R +   I   P     I +     L I N +  D GT+ C A    
Sbjct: 814  CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 4800 GQVETSAKLVV 4810
            G++++   + V
Sbjct: 874  GKIQSETTVTV 884



 Score =  115 bits (276), Expect = 5e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 4237

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 4238 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 4287

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 4288 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 4344 YVKEP-------PVFKG-DYPSNWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 4388

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 4389 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 4441

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 4442 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 4497

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 4498 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score =  113 bits (271), Expect = 2e-23
 Identities = 103/405 (25%), Positives = 158/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 1227

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 1282

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + EDGT  L+I    P D+G+Y CVA+
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAV 1341

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDK---------------EQVTNVSVLLNQLTNLFCEVEG 1386

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 1387 TPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P      ++ V   +    + Q+     P I W ++G  L    P
Sbjct: 1445 NIDVLVPPTIIGTNFP-----NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 1500 NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  110 bits (264), Expect = 1e-22
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI-VPGGRTLQI 3022

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N+ G +K   +L V           VPPS     + +   VNV
Sbjct: 3023 IR-AKVSDGGEYTCIAINQAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 3071

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 3129

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 3174

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 3235 KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  109 bits (261), Expect = 3e-22
 Identities = 100/368 (27%), Positives = 151/368 (41%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 3271 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 3330

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         TL   ++N+        + + TGT P  + WLKNG  
Sbjct: 3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI--------ECRATGTPPPQINWLKNGLP 3382

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 3383 LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 3438

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 3439 ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 3486

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 3487 HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 3541

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 3542 VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 3598

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 3599 CLASSPAG 3606



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 3054 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI--LAD 3111

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 3112 GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 3161

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 3267

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 3268 CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L  +V         + + T    P I WL+ G  +P
Sbjct: 3328 EDRIFNLNVYVTPTIRGNKDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLP 3384

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 3385 LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 3420



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/407 (25%), Positives = 164/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 4043

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 4093

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMA 4150

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 4151 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 4194

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 4195 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 4250 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 4301

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+    + VK
Sbjct: 4302 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346



 Score =  106 bits (255), Expect = 2e-21
 Identities = 91/382 (23%), Positives = 165/382 (43%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P++ W ++  P+K + + +I     K  ++  Q    D   +  VA +  G
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAG 1719

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWL 4548
              +    + V          +VPP+     +     V    L+ LD  VTG+ P  + WL
Sbjct: 1720 EKEIKYEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWL 1769

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P  
Sbjct: 1770 KDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP-- 1825

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  K++         L +++V + + +   C   G P P++ W K D+ +  ++ 
Sbjct: 1826 -----PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ- 1871

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              +   +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L 
Sbjct: 1872 GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LN 1929

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            + V+    P Q + +      P I W ++  L+  +     ++ G   ++ I +    D 
Sbjct: 1930 ETVLV-SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDA 1986

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A  +AG  E    L V
Sbjct: 1987 GIYKCVAINSAGATELFYSLQV 2008



 Score =  105 bits (253), Expect = 3e-21
 Identities = 122/485 (25%), Positives = 195/485 (40%), Gaps = 59/485 (12%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            ++ G P P +SW + + P+    K +       G  +L I +    D GEYTC A NQ G
Sbjct: 2987 EVSGFPPPDLSWLKNEQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 154  EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
            E+      +VY+ P                   S ++E ++                  Y
Sbjct: 3043 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITW--------Y 3094

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
             NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 3095 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 3152

Query: 268  IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
            I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 3153 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIA 3212

Query: 327  NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 3213 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 3253

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                         D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 3254 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREG 505
            +  L I     SD+G  TCVA N +GE      LNV     +   K   E+  TL     
Sbjct: 3302 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTL---VD 3357

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              + +  RA GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A
Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVA 3415

Query: 566  QNVAG 570
             N AG
Sbjct: 3416 SNRAG 3420



 Score =  105 bits (252), Expect = 4e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 3420

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 3421 VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 3471 RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 3526

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 3527 -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 3573

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 3574 -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 3629

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 3687

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 3688 ANYTCVASNIAGKTTREFILTV 3709



 Score =  105 bits (251), Expect = 5e-21
 Identities = 101/395 (25%), Positives = 161/395 (40%), Gaps = 35/395 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP    + Q   V   +      + D  P P + W ++  P+   P   I     +S+L 
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTS 4527
            I    V+D+  +   A N  G  + + N+ +           VPP+   + +   + V  
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW----------VPPNIGGSDELTQLTVIE 2210

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G L+ L  + +G  P ++ W K G  V  D   ++    G   L I  A   D+  Y CV
Sbjct: 2211 GNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCV 2270

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG A+ +    V +  T       T + + P EI       IV  G++I   C++ 
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPT------ITNSGSHPTEI-------IVTRGKSISLECEVQ 2317

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PTV W K G  LIK +K  ++    + + L++      D G Y CVA N AG    
Sbjct: 2318 GIPPPTVTWMKDGHPLIK-AKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2374

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V  P     +       +I V E        + +    P+I W ++G  +  +  
Sbjct: 2375 KYDLSVHAPPSI--IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNS 2432

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +++  G   +L +  T  ED G +TC    AAG+
Sbjct: 2433 VRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score =  104 bits (250), Expect = 7e-21
 Identities = 109/409 (26%), Positives = 167/409 (40%), Gaps = 41/409 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 850

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 851  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 902

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 903  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 959

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 960  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 1003

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSS-AKFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYAK 1061

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +   L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V
Sbjct: 1122 PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score =  104 bits (250), Expect = 7e-21
 Identities = 96/377 (25%), Positives = 155/377 (41%), Gaps = 34/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P  +W + +  +  +P   + +  +   L I +V ++D   +  VA N  GT   +
Sbjct: 916  GNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT 972

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             ++VV           V P+     Q ++   G  V L  K +G     V W K G+ + 
Sbjct: 973  TSVVVH----------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                      DG+  L ++    ++SG+Y C A N+AG A+   +  V +       +P+
Sbjct: 1023 TSSAKFSAGADGS--LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYV-------RPR 1073

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT- 4674
                       +P++  ++A G+ +   C++   P P + W K  +LI P   F    T 
Sbjct: 1074 VFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITWAKETQLISP---FSPRHTF 1129

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +++I+E    D G Y CVA N AG VT A KL V  P +    P     + + V  
Sbjct: 1130 LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQV 1184

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            GQ             P I W + G+ +    D +      +  L I      D G +TC 
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCV 1242

Query: 4795 ATTAAGQVETSAKLVVK 4811
            AT  AG  ET   L V+
Sbjct: 1243 ATNIAGTDETEITLHVQ 1259



 Score =  104 bits (250), Expect = 7e-21
 Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKE 1817

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 1818 FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 1868 NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 1919

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK ++L+  S    M+  
Sbjct: 1920 SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFL 1970

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1971 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 2025

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +    DTG +TC 
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSAQISDTGRYTCV 2084

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 2085 AVNAAGEKQRDIDLRV 2100



 Score =  104 bits (250), Expect = 7e-21
 Identities = 102/369 (27%), Positives = 147/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W + +  I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 3237 YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 3286

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 3287 IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 3339

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +  L D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 3340 PTIRGNKDEAEKLMTLVDT------SINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 3391

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 3392 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 3448

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3506

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 3507 IASNEAGEV 3515



 Score =  104 bits (249), Expect = 9e-21
 Identities = 101/398 (25%), Positives = 164/398 (41%), Gaps = 40/398 (10%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVF 4474
            KM    V      + E +  G P+P+I WY++N  +  S      TF  +  +I I    
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSM---TFLNRGQIIDIESAQ 1982

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + D+ ++  VA N  G  +   +L V           V PS + +   V V     VRL+
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH----------VAPSISGSNNMVAVVVNNPVRLE 2032

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +  G     + WLK+G  V     N +    G   L +  A   D+G+Y CVA+N+AGE
Sbjct: 2033 CEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             + D +  V +                PP I+   ++  V   QA+E  C+    P PT+
Sbjct: 2092 KQRDIDLRVYV----------------PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135

Query: 4655 QWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             W K G  L+K      +S + +   L+I +A  +D G Y C A N AG+      + + 
Sbjct: 2136 TWLKDGHPLLKKP---GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHE 4772
             P    N+     L  + V EG       + +    P + W ++G+ ++ ++     I  
Sbjct: 2193 VP---PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS 2249

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G    L I    + D   ++C A+  AG  +    L V
Sbjct: 2250 GGRQ-LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286



 Score =  102 bits (245), Expect = 3e-20
 Identities = 96/389 (24%), Positives = 155/389 (39%), Gaps = 31/389 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  +   R E E  G P P + W ++  P+ +  +  +   S   IL +    + D+  +
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRY 2081

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G  +   +L V           VPP+     QNV+V   Q V L  +     
Sbjct: 2082 TCVAVNAAGEKQRDIDLRV----------YVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  + WLK+G  +       I E      L I +A  QD+G+Y C A N AG+   +   
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNVAGKTEKNYNV 2189

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             + +P       P    +       + L    V EG  I   C+  G P P + W K   
Sbjct: 2190 NIWVP-------PNIGGS-------DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +      ++   +    L+IS A   D   Y CVA N AG       L+V       N 
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
             +     +I+V  G+    + ++     PT+ W+++G  + +    +++ EG+  +L + 
Sbjct: 2296 GSHPT--EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQLK 2351

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            N +  DTG + C A   AG  +    L V
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380



 Score =  101 bits (243), Expect = 5e-20
 Identities = 101/380 (26%), Positives = 148/380 (38%), Gaps = 35/380 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 1006 GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPGG-EESGEYVCTATNTAGYAKRK 1063

Query: 4496 ANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V  + R    + G+           ++V +G+ V L  +V    P  + W K  + 
Sbjct: 1064 VQLTVYVRPRVFGDQRGLSQDK----PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 1119

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P          G+  + I E    DSG Y CVA N AG      +  V          
Sbjct: 1120 ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV---------- 1167

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S 
Sbjct: 1168 ------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIV 4731
               + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V
Sbjct: 1222 P--DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 1279

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                Q  +F        KPTI+WL  G  L    P   ++ +G   +L+I +    D G 
Sbjct: 1280 A--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGE 1335

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A   AG  E    L V
Sbjct: 1336 YICVAVNEAGTTERKYNLKV 1355



 Score =  101 bits (241), Expect = 8e-20
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 3912

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 3970

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 3971 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 4013

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 4014 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 4071

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 4072 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 4126 RVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 1242 VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 1293

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 1294 PKPTIKWLHNGRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 1353 LKVH----------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 1400

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 1453

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 1506

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 1507 GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 1561

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 1562 NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 1619

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 1620 VANVAGTAEKS 1630



 Score =  100 bits (239), Expect = 1e-19
 Identities = 106/423 (25%), Positives = 169/423 (39%), Gaps = 31/423 (7%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKK-MQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T +   A  +ER + G      P I  +  ++  +V E +      E  G P+P I W++
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK 2515

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRR 4505
            +  P++   D   H  S    L I  V V  +  +  +A +  G    S +L V      
Sbjct: 2516 DGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
             G G    P      ++V V       L  +     P  + W K+G  ++ +   +IL  
Sbjct: 2574 AGVGSDGNP------EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL-- 2625

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             G  TL IL A   ++G+Y CVA N AGE     E  V +P   +K         +P E+
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL-SPKEV 2684

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
                K K+      +   C+    P  ++ WYK  + +K   +  ++  A+ +TL+I EA
Sbjct: 2685 ----KIKV---NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA--ANGHTLQIKEA 2735

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-------VVYEGQPA 4738
               D G Y CVA N AG   +   + +  P     L  +  + D         V    P 
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +  +   PT+ W ++G   P T   +++      VL I     ED G +TC A   
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNE 2853

Query: 4799 AGQ 4801
            AG+
Sbjct: 2854 AGE 2856



 Score =   99 bits (238), Expect = 2e-19
 Identities = 82/299 (27%), Positives = 123/299 (41%), Gaps = 40/299 (13%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P    +  G     + ++ G P P VTW K+G  LI +   EI+    H  L+++N   S
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGH-ILQLKNIHVS 2356

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            D+G Y  +A N  G       L+V +P  S + + RS                       
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHRS----------------------- 2392

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ + V +   V+        C  +G P P +TWF +   +    + +IL   SG   L 
Sbjct: 2393 PENISVVEKNSVS------LTCEASGIPLPSITWFKDGWPVSLSNSVRIL---SGGRMLR 2443

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +   T+ D+G  TCV RN +GE      L+V+    +V    +E    + V+E + V L 
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE---DVKVKEKQSVTLT 2500

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG P+    +   H   G   L I   +      Y C A + AG
Sbjct: 2501 CEVTGNPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 35/375 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E E  G P P + W ++  P+  +   +I       IL ++ + V D+  +  VA N  G
Sbjct: 2313 ECEVQGIPPPTVTWMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT---LTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
                  +L V            PPS      + +N++V     V L  + +G     + W
Sbjct: 2371 MTDKKYDLSVH----------APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITW 2420

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G  V   + N +    G   L +++   +D+G+Y CV  N+AGE R      V +P 
Sbjct: 2421 FKDGWPVS--LSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP- 2477

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                  P     N        L+D  V E Q++  +C++ G P+P + W+K  + ++  +
Sbjct: 2478 ------PHIVGENT-------LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               +   +    L+I+       G Y C+A + AG  + +  L V        + +    
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
             D+ V    P     +  S    TI W ++G  +    + +++  G    +L  N  E++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL--NAQEDN 2640

Query: 4788 TGTFTCRATTAAGQV 4802
             G ++C AT  AG++
Sbjct: 2641 AGRYSCVATNEAGEM 2655



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 95/380 (25%), Positives = 157/380 (41%), Gaps = 34/380 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E +  P P + WY++  P+ +S    I       +L I +  VED+  +  VA N  G  
Sbjct: 2800 ETNAAPPPTLTWYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857

Query: 4493 KCSANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                ++ V+     +G    +P       + V V   +   ++   +G+      W K+G
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLP-------EEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2910

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            + +  D  +K L       L IL     D G+Y CVA N+AG A+               
Sbjct: 2911 QPLLEDDHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAK--------------- 2953

Query: 4612 PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             K      + PP +I P  + + V     I  +C++ G P P + W K ++ IK +    
Sbjct: 2954 -KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +       TL+I  A   D G+Y C+A N AG       L V  P    +  + + L  +
Sbjct: 3013 I--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-LSVV 3069

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG     + +  +   P I W + G +I E+   +++ +G   +L I      DTG 
Sbjct: 3070 NVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQ 3127

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + CRA   AG+ + +  L V
Sbjct: 3128 YVCRAINVAGRDDKNFHLNV 3147



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 88/301 (29%), Positives = 127/301 (42%), Gaps = 37/301 (12%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 1051

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 1052 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 1090

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 1091 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 1143

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 579  Y 579
            +
Sbjct: 1257 H 1257



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF 4137

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 4138 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 4184

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 4185 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 4241

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 4242 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 4286 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKAIG 4341

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 4394

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 4395 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 88/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 1227

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 1268

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 1269 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 1318

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
             G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ + ++V  
Sbjct: 1319 DGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVTNVSVLL 1374

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 1375 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCK 1432

Query: 565  AQNVAGST 572
            A N+AG++
Sbjct: 1433 AINIAGTS 1440



 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 96/388 (24%), Positives = 160/388 (41%), Gaps = 36/388 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E        E  G PLP I W+++ +P+  S   +I   S   +L + Q  +ED+  +
Sbjct: 2398 VVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRMLRLMQTTMEDAGQY 2455

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTG 4539
              V  N  G          EE++  G   +VPP      T ++V V   Q V L  +VTG
Sbjct: 2456 TCVVRNAAG----------EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                ++ W K+G+ +Q D  + I+   G   L I       +G+Y C+A + AG      
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
               V +      P      ++  PE      D  V         C+    P  T+ W+K 
Sbjct: 2564 SLNVFV-----SPTIAGVGSDGNPE------DVTVILNSPTSLVCEAYSYPPATITWFKD 2612

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP---D 4716
               ++ ++  ++       TL+I  A  ++ G Y CVA N AG +    ++KV  P   +
Sbjct: 2613 GTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2670

Query: 4717 QADNL-PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
            + D   P L+P +++ +        + +  +    ++ W ++G   P   D  +    N 
Sbjct: 2671 KGDLWGPGLSP-KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ--PLKSDDHVNIAANG 2727

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              L I      DTG +TC A+  AG+ E
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDE 2755



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 64/209 (30%), Positives = 88/209 (42%), Gaps = 8/209 (3%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYP 421
            +   QY    +    EER       L P  +      +D  V E +     C VTG P P
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            E+TW  + + +++D  H I+   SG   L ITNV +  +G  TC+A + +G  +    LN
Sbjct: 2510 EITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V     +           + V    P  L   A   P   ITW KDG P+  N  +RI  
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2626

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G  TL I  A+  +A  Y C A N AG
Sbjct: 2627 --GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 3896

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 3951

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 4006

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 4007 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 4065 GTALGKIKL 4073



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 99/397 (24%), Positives = 159/397 (40%), Gaps = 41/397 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N  V  
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1934

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+ + +        L       + I  A   D+G Y+CV
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1992

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1993 AINSAGA----TELFYSL------------QVHVAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++ A   D G Y CVA N+AG    
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 2095 DIDLRVYVPPN-----IMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              +    N +VL I +   +DTG +TC AT  AG+ E
Sbjct: 2150 LSI--SENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 96/379 (25%), Positives = 156/379 (41%), Gaps = 42/379 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W   +  I  S  +++ +  T   L I+    +D+ ++  +A N  GT K +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            + L   E           P   +    + V  G +  ++ K +G  P  V W K   +++
Sbjct: 694  STLRYIEA----------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P   +  L  D    LL I E    D+G Y CVAIN AG A                   
Sbjct: 744  P---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI--------------- 785

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             T    +PP  I+   D  +  G  +   C + G P PT++W + D +   S+ F +S  
Sbjct: 786  -TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 4675 ADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +   T  L I   +  D+G Y C A N  G+  + ++  VT       L  ++P    V+
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK--IQSETTVTVTGLVAPLIGISPSVANVI 902

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQ      T +     P  +W++  A++ + P   +  +G+   L I     +D G +
Sbjct: 903  -EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEY 958

Query: 4792 TCRATTAAGQVETSAKLVV 4810
            TC A+  AG    +  +VV
Sbjct: 959  TCVASNVAGTNNKTTSVVV 977



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 86/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ +  G     + W 
Sbjct: 1533 KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY 1582

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 1583 KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 1638

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   CK  G P P + W K    +K +  
Sbjct: 1639 -----PMIEG-----NLATPLNKQVVI-AHSLTLECKAAGNPSPILTWLKDGVPVKANDN 1687

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             ++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 1688 IRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 1742

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G LI E   F+++  G    L+I      +T
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNT 1800

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTV 1822



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V+G P P+++W  N++ I+ + N  I+    G   L I    +SD G  TC+A N++G
Sbjct: 2986 CEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 3043 ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3101

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 3102 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 3137



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 87/367 (23%), Positives = 146/367 (39%), Gaps = 17/367 (4%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W+++  P++++ + +I        L I     +++  ++ VA N  G       
Sbjct: 2603 PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V       +G +  P   L+ + V +     + L+ +        + W K+G+ ++ D
Sbjct: 2661 VKVYIPPIINKGDLWGPG--LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2718

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                I      +TL I EA   D+G+Y CVA N AGE   D +  + +P +  K      
Sbjct: 2719 DHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
              +         KD I+     I   C+    P PT+ WYK G  L    K   +     
Sbjct: 2777 MLDTGRN--GEAKDVII--NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PG 2829

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L+I  A  ED G Y CVA N AG  ++   ++V  P       +  P  ++ V   +
Sbjct: 2830 GRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP-EEVTVLVNK 2888

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  +   +    P   W ++G  + E    + +   N  +L I NT   D G + C A 
Sbjct: 2889 SALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRILQILNTQITDIGRYVCVAE 2946

Query: 4797 TAAGQVE 4803
              AG  +
Sbjct: 2947 NTAGSAK 2953



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 3607

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 3608 -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 3661

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 3662 LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 3712

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 3713 PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 3762

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 3763 LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 3815

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 3816 IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 3875

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 3876 CTVTNGAGDDKRTVDLTVQ 3894



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 3553 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 3602

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 3603 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 3640

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
              +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 3641 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 3696

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 3697 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 3752 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 4064

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 4065 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 4119

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 4120 VESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 1835 ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 1892

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 1893 AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1947

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1948 PVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 2000



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 13/217 (5%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
            R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  + + I +    KIL+N      L+I    +S++G+  C+A N +G+   +  + V 
Sbjct: 1767 MWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTD 542
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I + 
Sbjct: 1824 VPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSS 1879

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 1880 G--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 49/290 (16%)

Query: 293  PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGY 352
            P   +TWFK+G  L ++    I+      TL++ N Q+ ++G Y+ +A N  G ++    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            + V  P                       + ++    L+P+ VK+  +  +T       +
Sbjct: 2661 VKVYIPP-------------------IINKGDLWGPGLSPKEVKIKVNNTLT------LE 2695

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C     P   ++W+ + + ++ D +  I  N    H L I    +SD+G  TCVA N +G
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAG 2752

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNV----REGE--------PVVLNARAVGTPTP 520
            E      +N+      V P F + +   N+    R GE        P+ L       P P
Sbjct: 2753 EDELDFDVNI-----QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2807

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +TW KDG P+  + ++ I    G   L IPRAK  DA  Y C A N AG
Sbjct: 2808 TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAG 2855



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 52/350 (14%)

Query: 229 RLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGAD 282
           R L  +S   +S+     GE    +S+E   S   V      PPK+   P+N     G++
Sbjct: 569 RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSE 628

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
                  +G P+P++ W  N   ++ S+++ + +     TL ++N    D+G Y      
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY------ 679

Query: 343 PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
             GC+ ++      + T+              +Q  T   IE      AP+ + V  +  
Sbjct: 680 --GCLASNS-----AGTD--------------KQNSTLRYIE------APKLMVVQSELL 712

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L I      D+G 
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGD 769

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TCVA N++G    +  L+V        P F++  + +++  G  V L     G P P I
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI 824

Query: 523 TWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            W++ D +PI   P  +   +      L I    ASD   Y C A+N  G
Sbjct: 825 KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFG 874



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/302 (24%), Positives = 132/302 (43%), Gaps = 33/302 (10%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P+  K++       + +    P   ++W+K+GQ L  S+ H  I  + HT L+++  Q S
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANGHT-LQIKEAQIS 2738

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR--ETEERIEISEKA 389
            D+G YT        C+ ++  +A E   +  V  Q    +  + Q+  E    ++     
Sbjct: 2739 DTGRYT--------CVASN--IAGEDELDFDVNIQ----VPPSFQKLWEIGNMLDTGRNG 2784

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
             A         +DV         C     P P +TW+ +   +    + K+L+   G   
Sbjct: 2785 EA---------KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS--SDKVLILPGGR-V 2832

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I    + D+G  TCVA N++GE + Q  + V+    ++     +    + V   +  +
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSAL 2891

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +   + G+P PR +WQKDG P++ +   +  ++G    L I   + +D   Y C A+N A
Sbjct: 2892 IECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNG--RILQILNTQITDIGRYVCVAENTA 2949

Query: 570  GS 571
            GS
Sbjct: 2950 GS 2951



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/311 (23%), Positives = 128/311 (41%), Gaps = 40/311 (12%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 3304 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 3348

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               +EK +         D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 3349 ---AEKLMT------LVDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLL- 3392

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 3393 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 3448

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 3449 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 3505

Query: 563  CTAQNVAGSTA 573
            C A N AG  +
Sbjct: 3506 CIASNEAGEVS 3516



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 3625 TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 3682

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 3683 DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 3732

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 3790

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 3791 TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 3895 VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 3950 GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 3984



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 3769

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 3819

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 3880 NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 3923

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 3980

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 3981 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4035

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 4036 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 9/163 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 2030 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSAQISDTGRYTCVAVN 2087

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 2088 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 2142

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P++  P L I  +   S L I  A+  D   Y C A NVAG T
Sbjct: 2143 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKT 2183



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 722  ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 779

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 780  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 829

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 830  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 885

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 886  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 936  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 986

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 987  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPGGE 1044

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 60/204 (29%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 380  EERIEISEKALAPQFVK-----VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            E+ ++   + L P  +K     + ++  V   K    +C  +G P P  +W  + + + +
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
            D +HK L N      L I N  ++D G   CVA N +G       LNV     V+ PK  
Sbjct: 2916 DDHHKFLSN---GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-- 2970

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
                 L V     + L     G P P ++W K+  PI  N    I    G  TL I RAK
Sbjct: 2971 --SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAK 3026

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD   Y C A N AG +  +  L
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSL 3050



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 101/475 (21%), Positives = 177/475 (37%), Gaps = 49/475 (10%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W +   P V   + +++  + +G V  + K +   D G YTC A N  GE  
Sbjct: 1852 GIPNPSITWLKDDQP-VNTAQGNLKI-QSSGRVLQIAKTLLE-DAGRYTCVATNAAGETQ 1908

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              + +                    VS  V+ +           +        +  T  +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
              +  ++   E   + +    + +     G      +TE+  SL     P I+       
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAG------ATELFYSLQVHVAPSISGSNNMVA 2022

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +      + + +  G P P +TW K+G   ++S  + +        L + + Q SD+G Y
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSP-VSSFSNGLQVLSGGRILALTSAQISDTGRY 2081

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T        C+      AV +  E              +QR+ + R+ +    +  +   
Sbjct: 2082 T--------CV------AVNAAGE--------------KQRDIDLRVYVPPNIMGEE--- 2110

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              Q+  V   +     C+    P P +TW  +   +       I  N S    L I +  
Sbjct: 2111 --QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---VLKIEDAQ 2165

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            + D+G  TC A N +G+T     +N+     +      +  + L V EG  + L   + G
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGS---DELTQLTVIEGNLISLLCESSG 2222

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             P P + W+K G P++ +   R+    G   L I  A+ SDAA Y C A NVAG+
Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 3503

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 3560

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 3561 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
            P  V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 1460 PNEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 1510

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 1567

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 1568 ECETRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 1625

Query: 571  S 571
            +
Sbjct: 1626 T 1626



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/281 (24%), Positives = 114/281 (40%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 1851 NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 1901

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 1902 NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1938

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+ ++R +    +   L   +    + I +  +SD+G+  CVA N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQIIDIESAQISDAGIYKCVAIN 1995

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1996 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +  A+ SD   Y C A N AG
Sbjct: 2051 P-VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 2090



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 13/177 (7%)

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            V  D  V    + + +C   G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 1553 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 1609

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
            +SDS   TC   N +G       ++V      V P      +T LN  V     + L  +
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECK 1664

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P+P +TW KDGVP+  N  +RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 12/168 (7%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 4236

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G
Sbjct: 4292 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 4315

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K    + V+E          PP F     +  +    G
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE----------PPVFKGDYPSNWIEPLGG 4365

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 4366 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 4421

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 4422 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 4464

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 4465 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 4520



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 52/187 (27%), Positives = 81/187 (43%), Gaps = 11/187 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+   + +++  T G      C  TG P P++ W +ND  I   + +++    + +  L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM----TSDGTLF 667

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V+ 
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVME 722

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N AG 
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGR 780

Query: 572 TATRARL 578
              +  L
Sbjct: 781 ATGKITL 787



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
            L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 1307 LTGREPGISILEDGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 1363

Query: 398  CQ---DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
             +   +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GKILKLFR 1420

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
             T  D+G  +C A N +G +     ++V+    ++   F    S +  R+   V L  + 
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD---VALECQV 1477

Query: 515  VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 1533

Query: 572  TATRARL 578
             A   +L
Sbjct: 1534 QAKDIKL 1540



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 909

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 966

Query: 570 GS 571
           G+
Sbjct: 967 GT 968



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 4426 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 4480

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 4481 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 4521



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG +    C  +G P P + W      +  D   ++ +  SG   L I+    SD+ +
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL-SGGRQLQISIAEKSDAAL 2266

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             +CVA N +G    +  L V  +  +         + + V  G+ + L     G P P +
Sbjct: 2267 YSCVASNVAGTAKKEYNLQVYIRPTIT--NSGSHPTEIIVTRGKSISLECEVQGIPPPTV 2324

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            TW KDG P+I    + I  +G    L +     SD   Y C A NVAG T
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAVNVAGMT 2372



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 4314

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G   F   +  +  ++   P F   + +  +   G   +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG---FVKAIGFVYVKE--PPVFKGDYPSNWIEPLGGNAIL 4369

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/345 (22%), Positives = 130/345 (37%), Gaps = 37/345 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I +V + D   +  +A +  GT +      V E          PP       NV VT 
Sbjct: 484  LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE----------PPPVIQVPNNVTVTP 533

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L   +      ++ W +N + V+     +I       +L +      D+G+Y C+
Sbjct: 534  GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCM 592

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              +  G +       V                  PP++    K++    G  +   C   
Sbjct: 593  VSSEGGSSAASVFLTVQ----------------EPPKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P P + W   D  I  S  ++M  T+D  TL I  A P+D G Y C+A NSAG     
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRM--TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            + L+  +  +      +    +++V  G     + + +    P ++W +    +   P  
Sbjct: 694  STLRYIEAPK-----LMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPST 746

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +I +    +L I  T + D G +TC A   AG+      L V S
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D  V     T   C     P   +TWF +   +  + N +IL    G   L I N    
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQED 2639

Query: 459  DSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            ++G  +CVA N++GE      + V     I K  +  P    +   + ++    + L   
Sbjct: 2640 NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE 2697

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   P+  ++W KDG P+  +  + I  +G   TL I  A+ SD   Y C A N+AG
Sbjct: 2698 AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAG 2752



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 3762 ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 3876

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 3877 TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 3932 KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 74/294 (25%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            +G+         G P P + W ++GQ L   + H  ++TH    L++   +  DSG YT 
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG-MVLQLLKAETEDSGKYTC 3506

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            +A N  G +     L V  P           +I  +++ E     EIS     P     C
Sbjct: 3507 IASNEAGEVSKHFILKVLEP----------PHINGSEEHE-----EISVIVNNP-LELTC 3550

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                +   KMT       GRP P+        Q++            G   L I+   + 
Sbjct: 3551 IASGIPAPKMTWMK---DGRPLPQTD------QVQ---------TLGGGEVLRISTAQVE 3592

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G  TC+A + +G+   +  + V     +         + L  R+   V L  ++   P
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ---VTLECKSDAVP 3649

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P ITW ++G  +   P +RI +  G   L I  A   D A Y C A N+AG T
Sbjct: 3650 PPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGKT 3701



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L I  V   D+G  TC+
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQIAFVQPGDAGHYTCM 4149

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 4150 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4204

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 4205 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 61/277 (22%), Positives = 112/277 (40%), Gaps = 28/277 (10%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            ++   V    P  + +++NG  +  D   + L+E  +  L I +    D G YEC+A++S
Sbjct: 448  QIPCSVDSLLPFTLSFVRNGVTLGVD---QYLKESASVNLDIAKVTLSDEGFYECIAVSS 504

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG  R      VS                 PP +I+   +  V  G+    +C I+    
Sbjct: 505  AGTGRAQTFFDVS----------------EPPPVIQVPNNVTVTPGERAVLTCLIISAVD 548

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
              + W + D+ ++ ++  ++ RT    +L +      D G+Y C+  +  G    +  L 
Sbjct: 549  YNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            V +P +   +P     ++     G         T   KP I W      I  +  ++M  
Sbjct: 608  VQEPPKVTVMP-----KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            +G    L I N   +D G + C A+ +AG  + ++ L
Sbjct: 663  DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 12/201 (5%)

Query: 402  DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
            +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 955

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 956  GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 1010

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             + W K G  +I     +  + G   +L +      ++  Y CTA N AG    + +L  
Sbjct: 1011 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068

Query: 581  XXXXXXXXXQKRLHLPRPTKV 601
                     Q+ L   +P ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEI 1089



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 12/188 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++V  +  VT G+     C +       +TW  NDR +R        +    N +L 
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVL 510
           + +V  +D+G   C+  ++ G +A    L V E  +V V PK        +   G  V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK------NQSFTGGSEVSI 631

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P+I W  + + I+ +   R+ +DG   TL I  A   DA  Y C A N AG
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688

Query: 571 STATRARL 578
           +    + L
Sbjct: 689 TDKQNSTL 696



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N+ G+++    L   
Sbjct: 2996 LSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   EC    V  P   I WY NG+ +  ST ++ 
Sbjct: 3054 VPPSIKDHDSESLSVVNV---REGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEI 3108

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 3109 LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 104/477 (21%), Positives = 174/477 (36%), Gaps = 55/477 (11%)

Query: 99   PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            P P ++W +   PL   +K  +      G   L I +    D G YTC A N+ GE    
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLIL----PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860

Query: 159  ----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                V + P                 + S  +E  + G+        +  Q +   +   
Sbjct: 2861 YDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--H 2918

Query: 215  HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
            H    + ++       + ++     + +   G +    +  +      V P  I  K  N
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-----VPPSVIGPKSEN 2973

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
              +          ++SG P P ++W KN Q  I  N + +I      TL++   + SD G
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQP-IKLNTNTLIVPGGR-TLQIIRAKVSDGG 3031

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERIEISEKALAPQ 393
             YT +A N  G       L V  P    ++D  S+ ++    RE T   +E    A+ P 
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSLECESNAVPPP 3089

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
             +   ++     G+M      +T   + E+   + D Q+   +  K  V+++G +     
Sbjct: 3090 VITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVSDTGQYVCRAI 3133

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV               +G       LNV     +  P+      T++     PV L   
Sbjct: 3134 NV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS----NPVTLTCD 3174

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C A N+ G
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 4432 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 4482

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 4483 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 4531



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C+  G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 1718

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  I
Sbjct: 1719 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 1776 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 1812



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 1238

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
             TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 1239 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 1296

Query: 521  RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W  +G  +    P + I  DG  + L I      D   Y C A N AG+T  +  L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 14/157 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA----EISVK 3137
            I WF +G  +E++  IR +   G   L+IL  +  ++G YSC ATN+ G+     E+ V 
Sbjct: 2607 ITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVY 2664

Query: 3138 L-ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +   ++K     P  +   + ++ +K   +   EC    +  P   + WY +GQP++   
Sbjct: 2665 IPPIINKGDLWGPGLSP--KEVK-IKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDD 2719

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +   ++ G   L I   Q  D+G Y C A N  GED
Sbjct: 2720 HVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGED 2754



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 62/288 (21%), Positives = 104/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 4132

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 4133 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4192

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 4193 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 4250

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 4251 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 4303

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +   G++ V+ P
Sbjct: 4304 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 3515

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 3516 SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3569

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 3570 PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 3608



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +  S  IR + A G V+  I+  + +D   Y+C A+N+ G    
Sbjct: 3367 TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYTCVASNRAGVDNK 3424

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L+            T  I  ++    G S    C       P M   W  +GQP+  
Sbjct: 3425 HYNLQVFAPPNMDNSMGTEEITVLK----GSSTSMACITDGTPAPSM--AWLRDGQPLGL 3478

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + TVS  G +VL +   +  DSG+Y C A N+ GE
Sbjct: 3479 DAHL-TVSTHG-MVLQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 17/203 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +L+IL T+ TD G Y C A N  G A+   ++ +       G K    T + N       
Sbjct: 2927 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN------- 2979

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                  C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C
Sbjct: 2980 NFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTC 3035

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----E 3280
             A N+ GE   + ++  Y    +     +  S+  +RE  S+    +     P      +
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3095

Query: 3281 PPKFITQIQDVTKLVEGQSAHFE 3303
              + IT+   V  L +GQ  H +
Sbjct: 3096 NGRMITESTHVEILADGQMLHIK 3118



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 64/257 (24%), Positives = 98/257 (38%), Gaps = 22/257 (8%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P + W +K +P++  +   +R    +G   L I      D   Y+C A N  G A 
Sbjct: 2222 GIPPPNLIWKKKGSPVLTDSMGRVRI--LSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279

Query: 157  ----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
                  VYI+P                R  S ++E +  G    T    +    +    G
Sbjct: 2280 KEYNLQVYIRPT-ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG 2338

Query: 213  TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES-DVQISTEIDRSLGPVSPPKIA-- 269
             +            E  +L+  +   S T RYV  + +V   T+    L   +PP I   
Sbjct: 2339 VEILD---------EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389

Query: 270  -QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             + P N  + E        + SG P P +TWFK+G  +  SN   I++      LR+  T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQT 2447

Query: 329  QKSDSGHYTLLAENPNG 345
               D+G YT +  N  G
Sbjct: 2448 TMEDAGQYTCVVRNAAG 2464



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 3728 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 3784

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 3785 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 3883



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           + ES +  L I  VTLSD G   C+A + +G    Q   +V E      P  ++  + + 
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE-----PPPVIQVPNNVT 530

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V  GE  VL    +      +TWQ++   +      RI T    S L++   K +DA  Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEY 589

Query: 562 QCTAQNVAGSTA 573
            C   +  GS+A
Sbjct: 590 HCMVSSEGGSSA 601



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 260  LGPVSPPKIAQKP--RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            L  + PP I  +    + K++E        +++GNP P +TW K+GQ L     H II+ 
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS- 2530

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L++ N Q   +G YT LA +P G
Sbjct: 2531 -GGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 86/218 (39%), Gaps = 35/218 (16%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            ++ IK       E     I  ++L   W KDG+P+++   +    N G+  L IK   + 
Sbjct: 2683 EVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQIS 2738

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEV 1037
            D G YTC A N  G+     ++ I          Q P   +K+  + +     +  E + 
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI----------QVPPSFQKLWEIGNMLDTGRNGEAKD 2788

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD 1097
             I   P                S + E    P   LT    WY +G  +TS++++     
Sbjct: 2789 VIINNP---------------ISLYCETNAAPPPTLT----WYKDGHPLTSSDKVLILP- 2828

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G   L I   + ED+G YT VA N AGE  L   + V
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 74/293 (25%), Positives = 118/293 (40%), Gaps = 46/293 (15%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   + WY +G+ L+      + ++ G  TL + +    D+G YTC A N  GE      
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGEDELDFD 2759

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            V            Q P   + L +I N+ D             TGR  E     KD++ I
Sbjct: 2760 V----------NIQVPPSFQKLWEIGNMLD-------------TGRNGEA----KDVI-I 2791

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +     + E +  P       + W+ +G  + +S ++  +   G  VL+I   K  D+G 
Sbjct: 2792 NNPISLYCETNAAPPP----TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGR 2845

Query: 3121 YSCRATNKWGQ--AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            Y+C A N+ G+   +  V++      KG        +  +      +SA  EC  +    
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLV----NKSALIEC--LSSGS 2899

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P  +  W  +GQP+      K +S+    +L I  TQ  D G YVC A N  G
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAG 2950



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 66/168 (39%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 4012 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4069

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 4070 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 4121

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L IA+ Q  D+G Y C A N  G   T   +  +
Sbjct: 4122 SIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 3236 YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 3287

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 3288 ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 4431

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG P+T+S ++  I   G V L I   + EDAG YT  AVN+ GE      
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVL-ILPGGRV-LQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862

Query: 860  IRVAARSTVT-ADLGIPEQ 877
            +RV     +  A+  +PE+
Sbjct: 2863 VRVLVPPIIKGANSDLPEE 2881



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   N   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 4404

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 4405 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 1311

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 1312 PGISILEDG-TLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            ++   EC++  +  P   V W  +G PL+ K +   I D G++ +    ++  D+G Y+C
Sbjct: 2308 KSISLECEVQGIPPPT--VTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSDTGRYVC 2363

Query: 4049 RATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
             A N+ GM + K  +     P I+ + + P+++  +EK
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 4194 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 4250 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 4300

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V     I        P      P N  
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWI 4360

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 4361 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 4417

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 2104 PNIMGEEQN 2112



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 18/164 (10%)

Query: 3079 SMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            S  + W+ +G+ +++   +  + A G   L+I   + +D+G Y+C A+N  G+ E+   +
Sbjct: 2703 SASLSWYKDGQPLKSDDHVN-IAANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV--PVD-------DPDMKIEWYHNG 3189
                    QK      I N+  L  G++   +  ++  P+         P   + WY +G
Sbjct: 2761 NIQVPPSFQK---LWEIGNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG 2815

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+  S ++  +   G  VL I   +  D+G Y C A N+ GED
Sbjct: 2816 HPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 3255 DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 3312

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            D+G YTC ATN  GE      L V     +     +    EK+  L DTS
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTI---RGNKDEAEKLMTLVDTS 3359



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  +  N     GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 4402

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  N   I  SHR R   + G + ++    K  D+G Y C A+N  G  + 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQ 692

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            +  L  ++  K         +Q+   +  G     EC    +  P +K  W+     +R 
Sbjct: 693  NSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGIPPPQVK--WFKGDLELRP 744

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLE 3250
            ST +  + D    +L I  TQ+ D+G+Y C A N+ G    + T++  G   V+++
Sbjct: 745  STFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD-VGSPPVFIQ 797



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 1170 PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 1268

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 1269 ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 1308

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 1309 GREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 1368 TNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 4078 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 4131

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 15/197 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP    V  ++  ++ G+ A     +I   D ++   W  N + +  +   R +  
Sbjct: 515  DVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLT--WQRNDRDVRLAEPAR-IRT 570

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               + LE+   K  D+G Y C  +++ G +  SV L        Q+P   T +   +   
Sbjct: 571  LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV------QEPPKVTVMPKNQSFT 624

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G      C+      P  KI W  N   +  S R +  SD    + + A     D+G Y
Sbjct: 625  GGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAA---PKDAGIY 679

Query: 3223 VCRAYNKYGEDFTRATI 3239
             C A N  G D   +T+
Sbjct: 680  GCLASNSAGTDKQNSTL 696



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PP    +P   +   G      C  TG+PKP++ W +N   IV   RY++T DG
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 4489 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 4544

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 4545 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGK 875



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 756  LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 809

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 810  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 870  ENQFGKIQSETTVTVTG 886



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 789  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 849  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 1371 SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDA 1426

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST-QNEAG--LEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +   NE    L +   LE + K      + 
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 1486

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 1487 WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C        A+T    G  I+ S +++Y++      
Sbjct: 1546 PSIKGGNVTTDI-SVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 1604

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 1605 IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++ +    + G   L +      D G Y C A +  GE
Sbjct: 1664 KAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV      +L++      D+G YSC+A N  G ++  
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVN--NGKILKLFRATPEDAGRYSCKAINIAGTSQKY 1443

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +           T+  N   +   +    EC V     PD  I W+ +G+P+   
Sbjct: 1444 FNIDVL----VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLG 1497

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 1498 DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +    G  I  E  ++ +  PT  + W+K+G  +   ++   I   G+I L + ++++ D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSD 2357

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
            +G Y C AV+  G+ + K  L V    +I    + PE +  +++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 35/210 (16%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++++  N     E     +  P   + W ++G P+++ + +    + G+  L +K    
Sbjct: 2682 KEVKIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQI 2737

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G YTC A N  GE      + +Q   S Q        L +I  + D+ R    +DV 
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ-------KLWEIGNMLDTGRNGEAKDVI 2790

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +            N P  L         C     P P +   WY +G  L S  +     
Sbjct: 2791 I------------NNPISL--------YCETNAAPPPTL--TWYKDGHPLTSSDKVLILP 2828

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
              G   L I     ED+G YTC A+N  G+
Sbjct: 2829 --GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 57/266 (21%), Positives = 102/266 (38%), Gaps = 11/266 (4%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            L GNP P   W +  A L++    ++R      D SL I+++   D GEYTC A N  G 
Sbjct: 914  LAGNPIPERRWIKNSAMLLQNPYITVR-----SDGSLHIERVQLQDGGEYTCVASNVAGT 968

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               +  +                    +  T+  KA G    +   S++ + ++ ++   
Sbjct: 969  NNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF 1028

Query: 215  HSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
             +  D    V +       E     + T  Y  +  VQ++  +   +          KP 
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYA-KRKVQLTVYVRPRVFGDQRGLSQDKPV 1087

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSD 332
               +  G +     ++   P P +TW K  Q +   S +H  + + +   +++  T+ SD
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSD 1144

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESP 358
            SG Y  +A N  G +  +  L V  P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVP 1170



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 3652 VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 3710 NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 3759

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 3760 YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 3801



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 3952

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 3996



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +G  +  S+ +R +   G  +L ++ T   D+G Y+C   N  G+      L  +
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P        +E +K  +      T     +P  +I W+ +GQP++       +
Sbjct: 2476 ------VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII 2529

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S   F  L I   Q   +G Y C A +  G      ++N +
Sbjct: 2530 SGGRF--LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2568



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  EC+   V      + W+KNG+ +T       + D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHL 3145



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 3299

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+  L 
Sbjct: 3300 NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTLV 3356

Query: 1960 DDS 1962
            D S
Sbjct: 3357 DTS 3359



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 4252 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 4306

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 4307 VN--GHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     S+ +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 4400

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     ED+G YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1385 CQATNQLGEAVTSCALRVIAKKDLILE 1411
            C ATN+ G    S +L + +   + LE
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 4364 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 4419 CVATNEAGVVERSMSLTLQS 4438



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    + KN  F  G          G P P ++WT     +V  ++Y M     T D +
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM-----TSDGT 665

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L IK   P D G Y C A N  G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAG 688



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I +  G     E  ++ I   T  V W+KDG P+  +  +    + G++ L +K++ V 
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI-LQLKNIHVS 2356

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            D G Y C A N  G      +L++     II   + P  +  ++
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G  +L I  V   DAGHYTC A N  G ++TS  LT+
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 1252 TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 1305

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 1306 ELTGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPII 1392



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 3676

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++ N    D+ +YT +A N  G       L V  P
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 3712



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 4429 ERSMSLTLQSPPIITLE 4445



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 20/170 (11%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDI---------IDESVTIKPRFVTRPKSIE 1454
            AK   IL+  H   L+ I ++ DT RY    +          D SV   P  +   +S E
Sbjct: 2336 AKGVEILDEGHILQLKNI-HVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE 2394

Query: 1455 N--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            N  V+E   V   C+   +   +  + WFK+G PV++ +  R +   G   L ++    E
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPS--ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTME 2450

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            D+G YTC   N  G +     L+      IV     E  LE ++V E +S
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLVPPHIV----GENTLEDVKVKEKQS 2496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632  RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 3429 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 3485

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
              G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 3486 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 3518

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 3519 FILKVLEPPHINGSEEHE 3536



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 3605 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 3655

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 3656 LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 3700



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 3766

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 3767 F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 12/174 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C ATN  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 1188

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 1189 DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 1244

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P
Sbjct: 1245 NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKP 1296



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 1579 ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 1635

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +  I+  
Sbjct: 1636 YVPPMIEGNLATPLN--KQVVIAHSLTLECKA--AGNPSPILTWLKDGVPVKANDNIRI- 1690

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 1691 -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG PV  S+ +      G   L +   T+ DAG YTC   NA G+      L+++
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 1003 TKKDIIAES 1011
                I+ E+
Sbjct: 2476 VPPHIVGEN 2484



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 3257 SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++  L D S
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTLVDTS 3359



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 1216

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 1217 HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 1256



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T   ++ S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 1496

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 1497 GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I V  G  +  +C V+ +  PT  + W  +G P      V  L++ G I L +  I+  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GHI-LQLKNIHVSD 2357

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
             G Y C A N  G       ++  A   I+   + P+ +S
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS 2397



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 3261 GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 3319 CVATNPAG 3326



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 4131

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 4132 --SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P+ +    N     G+ V + C     G    ++ W  N   I   HR+R   +
Sbjct: 606  LTVQEPPKVTVMPKNQSFTGGSEVSIMC--SATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI-AKKDLILESQHPSGLEKIQY 1423
                 L + +  P+D+G+Y C A+N  G    +  LR I A K ++++S+    L  I  
Sbjct: 664  G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITV 720

Query: 1424 LE 1425
            +E
Sbjct: 721  ME 722



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 714 ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 769

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 770 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 826

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 881

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 938

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAG 967



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 1351 YNLKVHVPPVIKDKEQ-------VTNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 1400

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 1401 VTESSTIQTVNN--GKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+  IR + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 1725 YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLIDE 1777

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 1778 RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 1813



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEK 2092

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 2093 QRDIDLRV 2100



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 633  VYPPPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V+ PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTN--TLIVP 3015

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            G  +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   V  EC  E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 3071 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 3127 QYVCRAINVAGRD 3139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LEC    +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 4433 SLTLQS 4438



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 860  IRVAARSTVTADLGIPEQRRYI 881
            + V     +  +L  P  ++ +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVV 1654



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ + + +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 2003

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 2004 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 2053

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +   Q  D+G Y C A N  GE
Sbjct: 2054 SFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVNAAGE 2091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G+ +  EC+++ +      V W K+G P+ I  +   I D G++ L + ++   D+G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSDTG 2359

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             Y C AVN+ G  +    L+  +   I+    N    E I V+E  S
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSII---GNHRSPENISVVEKNS 2403



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G++   E ++  +  PT  V W KDG P+  +  +  I + G++ L + ++   D G Y 
Sbjct: 2307 GKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGV-EILDEGHI-LQLKNIHVSDTGRYV 2362

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
              AVN  G       + V A  ++  +   PE    +EK
Sbjct: 2363 CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   EC     P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 3073 EGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 3302 STLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)

Query: 3047 PPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP  +   K+ ++ + +      EA  +P  D    I W  +G+ I  S R R V + G 
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPD----ITWHKDGRAIVESIRQR-VLSSGS 4132

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LK 3162
              L+I   +  D+G Y+C A N  G +  S KL     +    PR    I++ EG   + 
Sbjct: 4133 --LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL-----TVHVPPR----IRSTEGHYTVN 4181

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +   A   C    +  P   I W  +   + +     T   +G ++L+    +  DSG Y
Sbjct: 4182 ENSQAILPCVADGIPTP--AINWKKDNVLLANLLGKYTAEPYGELILENVVLE--DSGFY 4237

Query: 3223 VCRAYNKYGED 3233
             C A N  GED
Sbjct: 4238 TCVANNAAGED 4248



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 788  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 900

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 901  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 956

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 957  EYTCVASNVAG 967



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 1351 YNLKVHVPP 1359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 84/375 (22%), Positives = 143/375 (38%), Gaps = 32/375 (8%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            +NI V E   V   C  E  G P   I WF +G P +  + V  L+  G   L +     
Sbjct: 2394 ENISVVEKNSVSLTC--EASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTM 2449

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+YTC   N  G       ++      IV E+ L      EK        ++  P  
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E       + + + ++H +    G RF  ++   + P      Y      P+GH+ R+  
Sbjct: 2510 EITWHKDGQPLQEDEAHHI--ISGGRF-LQITNVQVP--HTGRYTCLASSPAGHKSRSFS 2564

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVND------FGEDFTKATISCKKLPDIILQNQVPR- 3935
               FVS  I  V ++ + E +   +N           +  ATI+  K    +  N+  R 
Sbjct: 2565 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI 2624

Query: 3936 --GMKRSEALTQMEATIKKYTSEVYLTEDDL---YDVDKKQPP------RFVTQIQSQTS 3984
              G +  + L   E    +Y+        ++   Y+V    PP       +   +  +  
Sbjct: 2625 LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEV 2684

Query: 3985 LVEMETT-KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
             +++  T   EC+   +  P+  + W+ +G+PL   +    I   G+  +        D+
Sbjct: 2685 KIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVN-IAANGH-TLQIKEAQISDT 2740

Query: 4044 GEYLCRATNLYGMDE 4058
            G Y C A+N+ G DE
Sbjct: 2741 GRYTCVASNIAGEDE 2755



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 4429 ERSMSLTLQS 4438



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 87/402 (21%), Positives = 156/402 (38%), Gaps = 41/402 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 791  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 966

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 967  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 1023

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDQRGLS 1082

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 1137

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +    DSG+Y C A N+ G    + +L       I R  ++
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 1544 IPPSIKGGNVTTDI----SVLINSLIKLECETRGLPMP--AITWYKDGQPIMSSSQALYI 1597

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 1598 -DKG-QYLHIPRAQVSDSATYTCHVANVAG 1625



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 2063

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 2064 GGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V  GK+   EC+V+ +  P   + +  +G  L  A    I  D G++ L +++    D G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTG 2359

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             Y   A+N  G       ++V A  SII   + PE +  + +   +   +   IP P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 3261 GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDT--QNEQAIEQIQLLEDAA 1295
              A N  G        R+   +  VT T   N+   E++  L D +
Sbjct: 3319 CVATNPAGEED-----RIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 3359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S      G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 4399

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL+L+S   +   +   +  S        V + V + P+ +T +      + G      C
Sbjct: 575  SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMC 633

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P  ++ W  N   +   HRYR ++D     L I     +D+G Y C A N+ G
Sbjct: 634  SATGYPKP--KIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 1927 QAVSSIRLN-VQSKESIIRDSQHESALEKIQYLE 1959
                +  L  +++ + ++  S+   AL  I  +E
Sbjct: 689  TDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 897  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 952

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 953  QDGGEYTCVASNVAG 967



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 1224

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
             +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 1225 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 1907

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY + + +
Sbjct: 1908 QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNRLL 1961

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1962 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1998



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +   + +D+G Y+C A N  G+ +  + L   
Sbjct: 2043 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVY 2101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 2102 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 2152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S+    VL I   Q  D+G Y C A N  G+      +N +
Sbjct: 2153 SE-NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 54/211 (25%), Positives = 82/211 (38%), Gaps = 34/211 (16%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            S K V+IK       E     +  A+L   WY + +PLKS        N G   L I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASLS--WYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSA 1702
               D+G YTC         V S IA    +    +  Q   +  +L ++ +     R+  
Sbjct: 2736 QISDTGRYTC---------VASNIA-GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
              +VI   P+           E  AA           P   + W ++G P+ +S+++  +
Sbjct: 2786 AKDVIINNPISLY-------CETNAA-----------PPPTLTWYKDGHPLTSSDKVLIL 2827

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G   L +     ED+G YTC A+NE GE
Sbjct: 2828 P--GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633  VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 3052 VYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTH-VEI 3108

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
               G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 3109 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 3154



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 3126

Query: 842  SYTVRAVNKLG 852
             Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             NL +     I          EK+  L D S
Sbjct: 3332 FNLNVYVTPTIRGNKDE---AEKLMTLVDTS 3359



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS+ I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 4403

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 4404 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 4461

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 4462 QATGEPQPTIT 4472



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 18/270 (6%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 1102 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATNIAG 1157

Query: 154  EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
                +V +                        +   A GT       S+    +   +G 
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 1216

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
             H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 1217 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 1269

Query: 272  PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
            P N+  QE    Q   F     G P+P + W  NG+ L    +  I    + T L + + 
Sbjct: 1270 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEDGTLLVIASV 1328

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               D+G Y  +A N  G       L V  P
Sbjct: 1329 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 22/283 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 1225

Query: 131  LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
            L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 188  H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                A GT        + T K  + NG + +  +       +  LL   S        Y+
Sbjct: 1286 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337

Query: 246  GESDVQI-STEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
              +  +  +TE   +L    PP I  K +  N  +          ++ G P P + W+K+
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 1398 NVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ I+     + +     +V  I   + +++G Y C A N  G    
Sbjct: 1759 TGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKK 1816

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 1817 EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 1865

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 1866 PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 724  AVLHVTPRATIE 735
              LHV    ++E
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQIS--DTGRYTCVAVNAAGEKQR 2094

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 2095 DIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P+++I++   S   EC +  +   +  V W  +G PL+    V+ +++ G  IL++  ++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GH-ILQLKNIH 2354

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
              D G Y C A N  G       L V     II   + P +
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            +L++     +D+G Y C A N  G  +    L      S     R   +I  +E  K+  
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE--KNSV 2404

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   E + +P+      I W+ +G P+  S  ++ +S  G  +L +  T   D+G+Y C 
Sbjct: 2405 SLTCEASGIPLPS----ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCV 2458

Query: 3226 AYNKYGED 3233
              N  GE+
Sbjct: 2459 VRNAAGEE 2466



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 34/215 (15%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+    +   EC  E Y  P+  + WY +G+ L+S      + + G   L I      D+
Sbjct: 2685 KIKVNNTLTLEC--EAYAIPSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDT 2740

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G YTC A N  G+      +N+Q   S          L +I  + D  R   A       
Sbjct: 2741 GRYTCVASNIAGEDELDFDVNIQVPPSF-------QKLWEIGNMLDTGRNGEA------- 2786

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
                         +V   +P+ L         PT+   WY +G P+      K     G 
Sbjct: 2787 ------------KDVIINNPISLYCETNAAPPPTL--TWYKDGHPLTSSD--KVLILPGG 2830

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              L I  A  ED G Y C A N  GE      V+V
Sbjct: 2831 RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 3122

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 3123 SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 3170

Query: 3548 LTPEAESGNPP 3558
            LT +A +G PP
Sbjct: 3171 LTCDA-TGIPP 3180



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 785  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 843

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 844  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 1006 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 1063

Query: 724  AVL--HVTPR 731
              L  +V PR
Sbjct: 1064 VQLTVYVRPR 1073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTV-NNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 860  IRVAARSTV 868
            I V    T+
Sbjct: 1446 IDVLVPPTI 1454



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+  +   +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 1510

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1952 ITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 2010 VAPSISGSN 2018



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            +++  + V   P      + PT++  + G+S   EC ++  P P   V W  +G  L   
Sbjct: 2279 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKA 2336

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                  ++     L +  ++  D+G Y C A+N  G       L+V +  SII    H S
Sbjct: 2337 KGVEILDEGHI--LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII--GNHRS 2392

Query: 1951 ALEKIQYLEDDS 1962
              E I  +E +S
Sbjct: 2393 P-ENISVVEKNS 2403



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +C    V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 3124

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 3125 TGQYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 3126

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626  PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 3661

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 3662 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 3529 EGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS 3588
            EG  + IA     +G   T    +E   PP     P+++ ++    A   C +I   D +
Sbjct: 494  EGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550

Query: 3589 MRVEWFHNGKP--LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            +   W  N +   L   +R++T+ +     LE+  V   DAG Y C  ++  G +  S  
Sbjct: 551  LT--WQRNDRDVRLAEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVF 605

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTE 3670
            L V+    + + P+  S F  G+E
Sbjct: 606  LTVQEPPKVTVMPKNQS-FTGGSE 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PPK     K+ +      V   C       PK +I W  N   +   HRYR   D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGY--PKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              +L I     +D+G Y C A N  G D   +T+   + P +++
Sbjct: 664  -GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 916 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 972

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 973 TSVVVHVLP--TIQHGQQILSTIEGI 996



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P+++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 1446 IDVLVPPTIIG-----TNFPNEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 1496

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 1497 GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 1405 KKDLILESQ-HPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            +K +I ++Q   +GL +         +KK    + +V + P   +   S   V++ + V 
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVA 1845

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
             +C    +   N  + W K+ QPV        I   G V L I   + ED+G YTC A N
Sbjct: 1846 LQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902

Query: 1524 LVGTDEVSCRL 1534
              G  +   +L
Sbjct: 1903 AAGETQQHIQL 1913



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S P   + W+KDG P+ ++  I  +   G  +L I++ + ++AG Y+  A N+ GE I  
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658

Query: 858  ASIRV 862
              ++V
Sbjct: 2659 YEVKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+G  L +   ++     G  TL I + + D++G Y+C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2732 IKI 2734
            +K+
Sbjct: 2661 VKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +C    V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 860  IRVAARSTV 868
            + V    T+
Sbjct: 3334 LNVYVTPTI 3342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 3829 GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 3886

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 3887 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 3945

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 3946 ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 3998

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 4056

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQVP 4078



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 4126

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 4127 VLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 791  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 850  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 994  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 1003 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 1058

Query: 154  EA----ICSVYIQP 163
             A      +VY++P
Sbjct: 1059 YAKRKVQLTVYVRP 1072



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/179 (21%), Positives = 72/179 (40%), Gaps = 7/179 (3%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W   G  +      R     G   L+I   + +D+  YSC A+N  G A+    L+    
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY-- 2287

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             +       +H   I  +  G+S   EC V  +  P   + W  +G P+  +  ++ + D
Sbjct: 2288 IRPTITNSGSHPTEII-VTRGKSISLECEVQGIPPP--TVTWMKDGHPLIKAKGVE-ILD 2343

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
             G  +L +      D+G YVC A N  G    +  ++ +    +      P++++ + +
Sbjct: 2344 EGH-ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E  + P  TI WF +G  + +    R     G   L IL    +++G Y C ATN+ GE 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 2194 VNTCTLKV 2201
            +    +KV
Sbjct: 2656 IKHYEVKV 2663



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIH--FETRIE----PVGDPTMKIEWLKNGQSI 679
            P GEEDR++    ++ P       E  K+    +T I       G P  +I WLKNG  +
Sbjct: 3324 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 3383

Query: 680  EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
              SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 3384 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 3421



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 3728 KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 3784 MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 3795

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 3796 IDLQVHVPP 3804



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 4151 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 4204

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 4205 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 1253 EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 1304

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 1305 RELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 1346



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 1259 QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 1312

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 1313 GISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 1354



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 653  KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            K+  ETR    G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC 
Sbjct: 1566 KLECETR----GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCH 1619

Query: 713  AVSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
              +  G AE    + V     IE     P   Q +
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 1654



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284  QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
            + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 1623

Query: 344  NGCIVTSGYLAVESP 358
             G    S ++ V  P
Sbjct: 1624 AGTAEKSFHVDVYVP 1638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+ + +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 2003

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 2004 YSLQVHVAP 2012



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKDG P+     ++   N     L I+   V D G YTC A N  G+   + N+ I
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ WY +G+ + S + +    + G+  L I   +  D+G YT VA N AGE +L   + +
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            +   S       + L+E          +  M       ++K V +   +NP        I
Sbjct: 2763 QVPPSF------QKLWE----------IGNMLDTGRNGEAKDVII---NNP--------I 2795

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C       PT+   W+ +G  +T  S  K     G   L I  A   D G YT  AV
Sbjct: 2796 SLYCETNAAPPPTL--TWYKDGHPLT--SSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851

Query: 1256 NHLGSAHTSAIVRVI 1270
            N  G       VRV+
Sbjct: 2852 NEAGEDSLQYDVRVL 2866



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 3253 PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 3309 ALTSDTGKYTCVATNPAGE 3327



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 3469 WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 3526

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 3527 PHINGSEEH 3535



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 3523 VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 3580

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 3581 GEVLRISTAQVEDTGRYTCLASSPAGD 3607



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 3767

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 4197 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254

Query: 1134 TV 1135
            TV
Sbjct: 4255 TV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 4268 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 4321

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G     G
Sbjct: 4322 DSGTYVCTAENSVGFVKAIG 4341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 4451 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 4506

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 4507 FECVARNLMG 4516



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  KI W  N+  +    RY+ T D +   L I +   +D+GIY C A+NS G+   + +
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 2863 LR 2864
            LR
Sbjct: 696  LR 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 994  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 1106

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 1107 PPPIITWAK 1115



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 265  PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP I     P    +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 1509

Query: 323  LRVRNTQKSDSGHYTLLAENPNG 345
            L ++N +++D G Y     N  G
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 7/149 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            SH   I+   G +I  EC V+    PT  + W  +  PL      +   D  ++ L + +
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKN 2352

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
             +  D+G Y C A N  G       L      +I  + + P+    +  VE+   +   +
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE---NISVVEKNSVSLTCE 2409

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEG 2926
                 +P   + K  W + ++   +++ G
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSG 2438



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   + W+ +G P++     +     G   L IL A  ++ G Y C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2067 VKV 2069
            VKV
Sbjct: 2661 VKV 2663



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 3124

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 3242 QVPPSVAGAEI 3252



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 3439 SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 3494

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 3535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 4100 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSS 4157

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 4158 STSTKLTVHVPPR--IRSTEGH 4177



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 4194 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 4251

Query: 997  ANLTI 1001
             +LT+
Sbjct: 4252 VSLTV 4256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 6/142 (4%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
            Q  + +    L I++    DEG Y+C+A +SAG         V++P     +P      +
Sbjct: 474  QYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVP-----NN 528

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V  G+ A     I S +   + W R    +    +   I    N  L + +    D G
Sbjct: 529  VTVTPGERAVLTCLIISAVDYNLTWQRNDRDV-RLAEPARIRTLANLSLELKSVKFNDAG 587

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C  ++  G    S  L V+
Sbjct: 588  EYHCMVSSEGGSSAASVFLTVQ 609



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK ++ W  N + I  S+R     D     L +K   P+D+G Y C A N  G    +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 1798 STL-FVQSKASLQLESQHESALQKIQQLE 1825
            STL ++++   + ++S+   AL  I  +E
Sbjct: 694  STLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 775  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449

Query: 1003 TKKDII 1008
                II
Sbjct: 1450 VPPTII 1455



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 3833 ITQIKSHTVE----ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            IT   SH  E      + +  EC V+    P   + W ++G  L        + D G + 
Sbjct: 2292 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI- 2347

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGM 3937
            L +  ++  D+G Y+C AVN  G    K  +S    P II  ++ P  +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2396



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            P   + WF +G  L      R     G   L IL   E+N+G Y CVATN+ G
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            DV    P+   C       PT+   W+ +G P  +  +V  L   G   L I      DA
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDA 2843

Query: 3766 GEYTCRATNKWG 3777
            G YTC A N+ G
Sbjct: 2844 GRYTCVAVNEAG 2855



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL TL D+ +
Sbjct: 3334 L------NVYVTPTI-RGNKDEAEKLMTLVDTSI 3360



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 3581

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 3685

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 3686 -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3744

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 3745 TWRKDGAVLAGNHARYSILENGFLHI---QSAH 3774



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L IA V+  D+G YT +A N AG +  S  +TV 
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAI 4187



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP + Q P N  +  G  A     +       +TW +N + +  +    I T  N  +L 
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLE 577

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
           +++ + +D+G Y  +  +  G    S +L V+ P +  V  +   +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSF 623



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 790  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 847  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 897  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 951

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 952  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 1236

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQE 1260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFET-RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            VY PP     L +    +    H  T   +  G+P+  + WLK+G  ++A+         
Sbjct: 1635 VYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR--IEA 1692

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
            G   L+++S    D G+Y C A S  G  E K  + V     IE
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 1736



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 2039 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDID 2097

Query: 860  IRV 862
            +RV
Sbjct: 2098 LRV 2100



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 2099 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 2156

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              + ++     +QD+G YTC A +  G  E
Sbjct: 2157 SVLKIE--DAQVQDTGRYTCEATNVAGKTE 2184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R+  NI  VE  +V L C     G     + WF +G P+   +  R         L L+ 
Sbjct: 2391 RSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQ 2446

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
               ED+G YTC   N  GE      L V+    ++ E+
Sbjct: 2447 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN 2484



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W+KDG P++ S+ +  I + G + L +M    EDAG YT    N  GE
Sbjct: 2414 PLPSITWFKDGWPVSLSNSV-RILSGGRM-LRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P+  + WYKDG+P+ +   +    N G+ +L I   +  D G YT  A N  GE
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGE 2753



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG P+ +S ++      G   L I    V DAG YTC A N  G+ +   ++ ++
Sbjct: 2811 WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+ N++EG     EC    +  P +T  W+ NG+ I          D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPVIT--WYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2177 EDSGTYMCKATNKLG 2191
             D+G Y+C+A N  G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 3147 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
               L +      DSG YTC A +  G A+
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 3449 KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 3504

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3536



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 3769

Query: 325  VRNTQKSDSGHYTLLAENPNG 345
            +++   +D+G Y  +A N  G
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAG 3790



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 4106 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162

Query: 860  IRV 862
            + V
Sbjct: 4163 LTV 4165



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 4419 CVATNEAGVVERS 4431



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 4427 VVERSMSL 4434



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 4433 SLTLQSPPIITLEPVE 4448



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKI 876



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + W KD R +  S+ +T F N G + + I+S  + DAG Y C A N+ G
Sbjct: 1952 ITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +  A  +DTG YT  A
Sbjct: 2029 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVA 2085

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 3261 GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTS 4160

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 4161 TKLTVHVPPRIRSTEGHYTVNENSQAI 4187



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP--FATGSR 3743
            T  D    PP   +++ +N+ V  G      C +    D    + W  N R    A  +R
Sbjct: 512  TFFDVSEPPP--VIQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPAR 567

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            + TL +   ++L++  +   DAGEY C  +++ GS+  +  +T
Sbjct: 568  IRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 700  EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 754

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 755  GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 798



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 1236

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTV 1264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++ +LL SG    T  + G + +DI      
Sbjct: 1929 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNRLL-SGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1985 DAGIYKCVAINSAG 1998



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 1176 KPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +P      S+P    V+ GK+I LEC ++ +  PT  V W  +G  +      +   +  
Sbjct: 2289 RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGH 2346

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
             + L  IH   +DTG Y   AVN  G       + V     I+ + ++ + I  ++
Sbjct: 2347 ILQLKNIHV--SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+ E QS    C +   P P   + W+ +G+ LQ    +   +   F  L I  V    +
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPE--ITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545

Query: 1915 GEYTCKAINNLGQAVSSIRLNV 1936
            G YTC A +  G    S  LNV
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNV 2567



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P D+ +  NS     C       ++  + WF +G PL +   ++ +   G   L+I    
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPAT--ITWFKDGTPLESNRNIRILP--GGRTLQILNAQ 2637

Query: 3624 QRDAGLYTCKATNRHGE 3640
            + +AG Y+C ATN  GE
Sbjct: 2638 EDNAGRYSCVATNEAGE 2654



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 51/193 (26%), Positives = 78/193 (40%), Gaps = 41/193 (21%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            P+  + W+ +G+P  +   V+   + G   L I      D G YTC A+N          
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASN---------- 2749

Query: 3785 ITCSAKRDIVLESQLPQGMSGEKIKE----LERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            I    + D  +  Q+P   S +K+ E    L+ GR  +A  ++ I++ P           
Sbjct: 2750 IAGEDELDFDVNIQVPP--SFQKLWEIGNMLDTGRNGEA--KDVIINNP----------- 2794

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
                  +   C       P L   WY++G  L S  +   +   G V L I     ED+G
Sbjct: 2795 ------ISLYCETNAAPPPTLT--WYKDGHPLTSSDKV-LILPGGRV-LQIPRAKVEDAG 2844

Query: 3901 EYICRAVNDFGED 3913
             Y C AVN+ GED
Sbjct: 2845 RYTCVAVNEAGED 2857



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+I++   S + E    P       + W+ +G PL +  +V  +   G  +L+I      
Sbjct: 2788 DVIINNPISLYCETNAAP----PPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVE 2841

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            DAG YTC A N  GE ++   ++V
Sbjct: 2842 DAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T+  T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 3354 TLVDTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 3409

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3519

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 3520 ILKV-------LEPPHINGSEEHEEI 3538



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 4438 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4494

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 4495 YIADAQ---KEDTSEFECVARNLMGS 4517



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P+     KN   T G  V +  + T    P  ++ W  N   +   HR++ T D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG- 664

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
               L I  A  +D G Y C A+N+ G     S+++
Sbjct: 665  --TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI W  N   +    R+++TSD    TL + +   +D+GIY C A N  G    +ST
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 3001 V 3001
            +
Sbjct: 696  L 696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 756

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 757  -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 794  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 854  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICV 1339

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 1340 AVNEAGTTERKYNLKV 1355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAG 1345



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   P  + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNF---PNEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 1493

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 1471 VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 1527

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 1528 SNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915

Query: 1136 ETRSSID 1142
                S++
Sbjct: 1916 HEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G  + LE  +  +  PT  V W  +G P+ +    +   D G++ L +   +  DTG
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTG 2359

Query: 2049 TYMCKATNAVG 2059
             Y+C A N  G
Sbjct: 2360 RYVCVAVNVAG 2370



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 8/144 (5%)

Query: 3962 DDLYDVDKKQPPRFVTQIQS--QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            D  YD+    PP  +   +S    S+VE  +    C+ +  G P   + WF +G P+   
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLS 2430

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
            N    +   G   +       ED+G+Y C   N  G +     +     P IV ++ L +
Sbjct: 2431 NSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-E 2487

Query: 4080 HMKSIEKIREMEASWQVTPEQVVE 4103
             +K  EK + +  + +VT   V E
Sbjct: 2488 DVKVKEK-QSVTLTCEVTGNPVPE 2510



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + W+ +G  L+S    R     G   L IL    +++G Y+C A N  G+ 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 1929 VSSIRLNV 1936
            +    + V
Sbjct: 2656 IKHYEVKV 2663



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV 3622
            +P ++ +  N++   EC    +  +S+   W+ +G+PL +   V    + G   L+I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 3623 YQRDAGLYTCKATNRHGE 3640
               D G YTC A+N  GE
Sbjct: 2736 QISDTGRYTCVASNIAGE 2753



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDL 1509
            PK ++  +    +  EC+   +  ++L   W+K+GQP+        I   G+  L I + 
Sbjct: 2681 PKEVKIKVNNT-LTLECEAYAIPSASLS--WYKDGQPLKSDDHVN-IAANGHT-LQIKEA 2735

Query: 1510 IAEDSGIYTCRAVNLVGTDEV 1530
               D+G YTC A N+ G DE+
Sbjct: 2736 QISDTGRYTCVASNIAGEDEL 2756



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/120 (30%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            EDS +Y  R  V   +  A    + L     +   +SA  EC     P P  R  W  +G
Sbjct: 2856 EDSLQYDVRVLVPPIIKGAN---SDLPEEVTVLVNKSALIECLSSGSPAP--RNSWQKDG 2910

Query: 1885 K-VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            + +L+  H    SN      L IL     D G Y C A N  G A     LNV    S+I
Sbjct: 2911 QPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2967



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 2986 CEVSGFPPPDL--SWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 3041

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 3042 GESKKKFSLTVYVPPS-IKDHDSES 3065



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 8/151 (5%)

Query: 2194 VNTCTLKVAGHRNI-ILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV---TELR 2249
            +NT TL V G R + I+  +  +G E       Q   ++ +       PP      +E  
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESL 3066

Query: 2250 GTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
               +V EG +   EC+   V  P   I +Y NG+ +  +    I  D G + L I+    
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
             D G+Y  +AIN  G       + V    SI
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 3447 VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 3502

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 3503 KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 3674

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 3675 RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 3722



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 3979

Query: 724  AVLHV 728
              LHV
Sbjct: 3980 VTLHV 3984



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 14/133 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 4217 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 4268

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 4269 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 4322

Query: 3219 SGEYVCRAYNKYG 3231
            SG YVC A N  G
Sbjct: 4323 SGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W +N + +    R+R T D    TL I +    DAG+Y C A N AG
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V    PV  +C+    G+P   I W+ + R   +GS   T  + G I +DI+     
Sbjct: 1929 NETVLVSNPVQLECKA--AGNPVPVITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3764 DAGEYTCRATNKWGS 3778
            DAG Y C A N  G+
Sbjct: 1985 DAGIYKCVAINSAGA 1999



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 3826 VSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNEQ--PIKLNTNTLIVP 3015

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            G  +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN+ GE+   
Sbjct: 2990 GFPPPDLSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 3108 ILADGQMLH 3116



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 2996 LSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 1003 TKKDI 1007
                I
Sbjct: 3054 VPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 724  AVLHVTPRATIERTSQHPETL 744
              L+V    TI       E L
Sbjct: 3332 FNLNVYVTPTIRGNKDEAEKL 3352



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 1791 LGE 1793
             G+
Sbjct: 3605 AGD 3607



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 3712 PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 3768

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 3769 HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 3887

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 3888 TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 3936

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 3937 LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 3985



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 3952

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 3993



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 4260 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 4312

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  +T +   ++   G      C       P +   W  N   I   HRYR T D   
Sbjct: 609  QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDMFIVGSHRYRMTSD--- 663

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
              L I     +D+G Y C A+N  G      TL+
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 1273 TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVT 1329

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 1330 PYDNGEYICVAVNEAGTTERKYNLKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 3510 MKV 3512
            +KV
Sbjct: 1353 LKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAG 1438



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 1671 SKKSI 1675
               S+
Sbjct: 1917 EPPSL 1921



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1946 GNPVPVITWYKDN-RLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L  +T +EG  I      E  G P   + W K G  +   S        G   L +    
Sbjct: 2203 LTQLTVIEGNLISL--LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE 2260

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
              D+  Y+C A +  G A+ +  L V  R TI  +  HP
Sbjct: 2261 KSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHP 2299



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG  + L  +      PNL   W K G  + T +  +     G   L I+     D+ 
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLI--WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2265

Query: 2714 IYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            +Y+C A+N+ G A    ++++  R  +     HP  +
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W+++G P+  +  +  + D G++ L +K ++  D+G Y C A+N  G     
Sbjct: 2318 GIPPPTVTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2375

Query: 1798 STLFVQSKASL 1808
              L V +  S+
Sbjct: 2376 YDLSVHAPPSI 2386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P   + W ++G P+E++  +  +   G   L +     +++G Y+C A NE GE +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 2963 PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GG 3017

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 3430

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 3431 FAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 3791



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 3744 ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3801

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 3802 VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 3852

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 3853 YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 4260 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 4312

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 945  WLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            W ++ R V  +  +RI T  N   ++L +KSV  +DAG Y C   +  G +  S  LT+ 
Sbjct: 553  WQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 1002 -VTKKDIIAESQHPGGLEKIQYLEDASRYSK 1031
               K  ++ ++Q   G  ++  +  A+ Y K
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPK 640



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    PK+ ++   G  V   C          K+ W  N   +   HR+R   D     
Sbjct: 612  PKVTVMPKN-QSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG---T 665

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L I +   +D+GIY C A N  GTD+ +  L
Sbjct: 666  LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            +T+T+   +   + +  + A    Q  + + V   P+  R   +++   G  V + C  Q
Sbjct: 1137 ITETRTSDSGMYLCVATNIAGNVTQAVK-LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G     + W   G  +        +     +++D  +  P D+G+YTC ATN  G   
Sbjct: 1196 --GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT--PSDAGIYTCVATNIAGTDE 1251

Query: 1396 TSCALRV 1402
            T   L V
Sbjct: 1252 TEITLHV 1258



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            +L C +E  G P+  + W+ +   VT  S  +T  + G + L +  AT  D G Y+ +A+
Sbjct: 1379 NLFCEVE--GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAI 1434

Query: 1256 NHLGSAHTSAIVRVIERSDIV-TDTQNEQAI 1285
            N  G++     + V+    I+ T+  NE ++
Sbjct: 1435 NIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 1465



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   + WYKD R ++ S+ +T   N G + ++I   +  DAG Y   A+N  G      
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 859  SIRVAARSTVT 869
            S++V    +++
Sbjct: 2005 SLQVHVAPSIS 2015



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ID  V + P  +   +++ +V+  Q V   C+ + +    L   W K+G P+ +      
Sbjct: 2096 IDLRVYVPPNIMGEEQNV-SVLISQAVELLCQSDAIPPPTLT--WLKDGHPL-LKKPGLS 2151

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            I +   V L I D   +D+G YTC A N+ G  E
Sbjct: 2152 ISENRSV-LKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3694 PPRFTVE-IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP    E   +++ V E   V   C V   G+P   I W  +G+P       H ++   F
Sbjct: 2477 PPHIVGENTLEDVKVKEKQSVTLTCEV--TGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2534

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I  +     G YTC A++  G
Sbjct: 2535 --LQITNVQVPHTGRYTCLASSPAG 2557



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  + E    P+  + W+K+G  L +   +    +    TL I   +  D+G YTC A+N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASN 2749

Query: 2722 LLGE 2725
            + GE
Sbjct: 2750 IAGE 2753



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 2/72 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KDG+P+        F + G + L I +  + D G Y C A N  G A   
Sbjct: 2898 GSPAPRNSWQKDGQPLLEDDH-HKFLSNGRI-LQILNTQITDIGRYVCVAENTAGSAKKY 2955

Query: 997  ANLTIVTKKDII 1008
             NL +     +I
Sbjct: 2956 FNLNVHVPPSVI 2967



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 14/146 (9%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYVALDLLSVY 1376
            N+  V    + L C +   G     + W  N +PIK  T     P        L ++   
Sbjct: 2973 NLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTNTLIVPGGR----TLQIIRAK 3026

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              D G YTC A NQ GE+    +L V       ++      L  +   E TS      + 
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTS----VSLE 3080

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHV 1462
             ES  + P  +T  K+   + E  HV
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHV 3106



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 3073 EGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 3129 VCRAINVAG 3137



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W +N K IE+S  +      G   + I+  +  D G Y C ASN+ G+
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 3318

Query: 146  CTARNQYGE 154
            C A N  GE
Sbjct: 3319 CVATNPAGE 3327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 3357 DTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 3412

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 3413 CVASNRAGVDNKHYNLQV 3430



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 3556 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613

Query: 860  IRV 862
            +RV
Sbjct: 3614 VRV 3616



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 3728 KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 3782

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  +G+ ++   R + ++      L+I  V   DAG YTC A N  G ++ S KL V
Sbjct: 4110 ITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 4364 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 4418

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 4419 CVATNEAG 4426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPP   VP  +VT   G +      I    D    + W +N + +  +     I     +
Sbjct: 519 PPPVIQVP-NNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEP-ARIRTLANL 574

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQ 739
           SL++ S+   D+GEY C   S  G +     L V   P+ T+   +Q
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 702  PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 757

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 758  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 799



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 1007 NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 1063

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 1064 VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 1118

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 1119 LISPFSPRH 1127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 1253

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQE 1277



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +E  P P   + WY +   +      +T N+     L +     ED+G Y+CKAIN  
Sbjct: 1382 CEVEGTPSPI--IMWYKDNVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIA 1437

Query: 1926 GQAVSSIRLNVQSKESII 1943
            G +     ++V    +II
Sbjct: 1438 GTSQKYFNIDVLVPPTII 1455



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1844 PRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            P  I   N P ++S    +    EC+++  P P+  + W+ +GK L  G       D G 
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRG- 1507

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L +      D G Y C   N  G+    I+L +    SI
Sbjct: 1508 QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 1548



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+     +   + G   L+I+ A   
Sbjct: 1650 NKQVVIAHSLTLECKAA--GNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEI 1705

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 1838 VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 1894

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 1895 RYTCVATNAAGE 1906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 1912

Query: 2199 LKV 2201
            L V
Sbjct: 1913 LHV 1915



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 2001 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 2057

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 2058 GLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 2109



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V   +PV LE     +  P++   W  +G PV            G + L +  A   DTG
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLT--WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTG 2079

Query: 2049 TYMCKATNAVGE 2060
             Y C A NA GE
Sbjct: 2080 RYTCVAVNAAGE 2091



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 2034 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVN 2087

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 2088 AAGEKQRDIDLRV 2100



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  + + Q+ + L+  +  +  CQ   +  P +   W  +G PLL K   +   +   +
Sbjct: 2103 PPNIMGEEQNVSVLIS-QAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENRSVL 2159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V  +D+G Y C ATN+ G  E    +     P I
Sbjct: 2160 KIEDAQV--QDTGRYTCEATNVAGKTEKNYNVNIWVPPNI 2197



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G ++ LEC +Q +   T  V W  +G P+          E     L L +++  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSD 2357

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            +G Y C A N  G       L V A   +I   + P  +  ++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P   + W ++G P+  SN +  +   G   L +     ED+G YTC   N  GE
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P ++ +  N SA  EC  +     + R  W  +G+PLL     K +++    IL+I    
Sbjct: 2879 PEEVTVLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQ 2934

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQV 3649
              D G Y C A N  G A     L V
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNV 2960



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/71 (33%), Positives = 31/71 (43%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N   IE S+ L      G   L +      DSG YTC A N  G+A   
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 1798 STLFVQSKASL 1808
              L +Q   S+
Sbjct: 3237 YFLSIQVPPSV 3247



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 4165 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 4222

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 4223 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 4426


>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-77J13 on chromosome 1. ).
          Length = 5635

 Score =  129 bits (312), Expect = 2e-28
 Identities = 107/384 (27%), Positives = 161/384 (41%), Gaps = 35/384 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  ++ A  E    G P P   W ++  P+      +    S   IL I    + D   +
Sbjct: 2884 VLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRILQILNTQITDIGRY 2941

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGT 4540
              VAEN  G+AK   NL V           VPPS     ++N+ V     + L  +V+G 
Sbjct: 2942 VCVAENTAGSAKKYFNLNVH----------VPPSVIGPKSENLTVVVNNFISLTCEVSGF 2991

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P D+ WLKN + ++ +    I+   G  TL I+ A   D G+Y C+AIN AGE++    
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V +P       P  K  ++     E L    V EG ++   C+    P P + WYK  
Sbjct: 3050 LTVYVP-------PSIKDHDS-----ESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3097

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            ++I  S + ++   AD   L I +A   D G Y C A N AGR      L V  P   + 
Sbjct: 3098 RMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155

Query: 4721 LPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                 P R+++V     P       T    PTI WL+    I  +   ++      + L 
Sbjct: 3156 -----PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVE 4803
            I  +   D+G +TC A+   G+ +
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQ 3234



 Score =  119 bits (287), Expect = 2e-25
 Identities = 103/380 (27%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 1148

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 1149 LCVATNIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 1257 HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 1305

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   D   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 1306 EL--TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               +T   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 1364 KEQVT---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKL 1418

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 1419 FRATPEDAGRYSCKAINIAG 1438



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/371 (27%), Positives = 155/371 (41%), Gaps = 39/371 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + W R +  ++ +   +I T +  S L ++ V   D+  +  +  + GG++  S  L V+
Sbjct: 551  LTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E          PP  T+  +N + T G  V +    TG     + W  N   +    R +
Sbjct: 610  E----------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYR 659

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             +  DGT  L I  A P+D+G Y C+A NSAG                DK     +   A
Sbjct: 660  -MTSDGT--LFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEA 701

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P +++    + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+
Sbjct: 702  P-KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLK 758

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I E    D GDY CVA N AGR T    L V  P      PA     D+ +  G      
Sbjct: 759  IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLP 813

Query: 4742 TQITSKIKPTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              +    +PTI+W R +   I   P     I +     L I N +  D GT+ C A    
Sbjct: 814  CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 4800 GQVETSAKLVV 4810
            G++++   + V
Sbjct: 874  GKIQSETTVTV 884



 Score =  115 bits (276), Expect = 5e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 4237

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 4238 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 4287

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 4288 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 4344 YVKEP-------PVFKG-DYPSNWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 4388

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 4389 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 4441

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 4442 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 4497

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 4498 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score =  113 bits (271), Expect = 2e-23
 Identities = 103/405 (25%), Positives = 158/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 1227

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 1282

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + EDGT  L+I    P D+G+Y CVA+
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAV 1341

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDK---------------EQVTNVSVLLNQLTNLFCEVEG 1386

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 1387 TPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P      ++ V   +    + Q+     P I W ++G  L    P
Sbjct: 1445 NIDVLVPPTIIGTNFP-----NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 1500 NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  110 bits (264), Expect = 1e-22
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI-VPGGRTLQI 3022

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N+ G +K   +L V           VPPS     + +   VNV
Sbjct: 3023 IR-AKVSDGGEYTCIAINQAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 3071

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 3129

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 3174

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 3235 KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  109 bits (261), Expect = 3e-22
 Identities = 100/368 (27%), Positives = 151/368 (41%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 3271 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 3330

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         TL   ++N+        + + TGT P  + WLKNG  
Sbjct: 3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI--------ECRATGTPPPQINWLKNGLP 3382

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 3383 LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 3438

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 3439 ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 3486

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 3487 HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 3541

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 3542 VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 3598

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 3599 CLASSPAG 3606



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 3054 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI--LAD 3111

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 3112 GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 3161

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 3267

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 3268 CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L  +V         + + T    P I WL+ G  +P
Sbjct: 3328 EDRIFNLNVYVTPTIRGNKDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLP 3384

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 3385 LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 3420



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/407 (25%), Positives = 164/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 4043

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 4093

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMA 4150

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 4151 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 4194

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 4195 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 4250 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 4301

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+    + VK
Sbjct: 4302 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346



 Score =  106 bits (255), Expect = 2e-21
 Identities = 91/382 (23%), Positives = 165/382 (43%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P++ W ++  P+K + + +I     K  ++  Q    D   +  VA +  G
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAG 1719

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWL 4548
              +    + V          +VPP+     +     V    L+ LD  VTG+ P  + WL
Sbjct: 1720 EKEIKYEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWL 1769

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P  
Sbjct: 1770 KDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP-- 1825

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  K++         L +++V + + +   C   G P P++ W K D+ +  ++ 
Sbjct: 1826 -----PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ- 1871

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              +   +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L 
Sbjct: 1872 GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LN 1929

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            + V+    P Q + +      P I W ++  L+  +     ++ G   ++ I +    D 
Sbjct: 1930 ETVLV-SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDA 1986

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A  +AG  E    L V
Sbjct: 1987 GIYKCVAINSAGATELFYSLQV 2008



 Score =  105 bits (253), Expect = 3e-21
 Identities = 122/485 (25%), Positives = 195/485 (40%), Gaps = 59/485 (12%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            ++ G P P +SW + + P+    K +       G  +L I +    D GEYTC A NQ G
Sbjct: 2987 EVSGFPPPDLSWLKNEQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 154  EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
            E+      +VY+ P                   S ++E ++                  Y
Sbjct: 3043 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITW--------Y 3094

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
             NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 3095 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 3152

Query: 268  IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
            I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 3153 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIA 3212

Query: 327  NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 3213 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 3253

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                         D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 3254 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREG 505
            +  L I     SD+G  TCVA N +GE      LNV     +   K   E+  TL     
Sbjct: 3302 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTL---VD 3357

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              + +  RA GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A
Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVA 3415

Query: 566  QNVAG 570
             N AG
Sbjct: 3416 SNRAG 3420



 Score =  105 bits (252), Expect = 4e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 3420

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 3421 VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 3471 RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 3526

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 3527 -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 3573

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 3574 -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 3629

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 3687

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 3688 ANYTCVASNIAGKTTREFILTV 3709



 Score =  105 bits (251), Expect = 5e-21
 Identities = 101/395 (25%), Positives = 161/395 (40%), Gaps = 35/395 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP    + Q   V   +      + D  P P + W ++  P+   P   I     +S+L 
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTS 4527
            I    V+D+  +   A N  G  + + N+ +           VPP+   + +   + V  
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW----------VPPNIGGSDELTQLTVIE 2210

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G L+ L  + +G  P ++ W K G  V  D   ++    G   L I  A   D+  Y CV
Sbjct: 2211 GNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCV 2270

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG A+ +    V +  T       T + + P EI       IV  G++I   C++ 
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPT------ITNSGSHPTEI-------IVTRGKSISLECEVQ 2317

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PTV W K G  LIK +K  ++    + + L++      D G Y CVA N AG    
Sbjct: 2318 GIPPPTVTWMKDGHPLIK-AKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2374

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V  P     +       +I V E        + +    P+I W ++G  +  +  
Sbjct: 2375 KYDLSVHAPPSI--IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNS 2432

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +++  G   +L +  T  ED G +TC    AAG+
Sbjct: 2433 VRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score =  104 bits (250), Expect = 7e-21
 Identities = 109/409 (26%), Positives = 167/409 (40%), Gaps = 41/409 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 850

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 851  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 902

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 903  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 959

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 960  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 1003

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSS-AKFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYAK 1061

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +   L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V
Sbjct: 1122 PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score =  104 bits (250), Expect = 7e-21
 Identities = 96/377 (25%), Positives = 155/377 (41%), Gaps = 34/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P  +W + +  +  +P   + +  +   L I +V ++D   +  VA N  GT   +
Sbjct: 916  GNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT 972

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             ++VV           V P+     Q ++   G  V L  K +G     V W K G+ + 
Sbjct: 973  TSVVVH----------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                      DG+  L ++    ++SG+Y C A N+AG A+   +  V +       +P+
Sbjct: 1023 TSSAKFSAGADGS--LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYV-------RPR 1073

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT- 4674
                       +P++  ++A G+ +   C++   P P + W K  +LI P   F    T 
Sbjct: 1074 VFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITWAKETQLISP---FSPRHTF 1129

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +++I+E    D G Y CVA N AG VT A KL V  P +    P     + + V  
Sbjct: 1130 LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQV 1184

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            GQ             P I W + G+ +    D +      +  L I      D G +TC 
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCV 1242

Query: 4795 ATTAAGQVETSAKLVVK 4811
            AT  AG  ET   L V+
Sbjct: 1243 ATNIAGTDETEITLHVQ 1259



 Score =  104 bits (250), Expect = 7e-21
 Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKE 1817

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 1818 FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 1868 NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 1919

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK ++L+  S    M+  
Sbjct: 1920 SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFL 1970

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1971 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 2025

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +    DTG +TC 
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSAQISDTGRYTCV 2084

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 2085 AVNAAGEKQRDIDLRV 2100



 Score =  104 bits (250), Expect = 7e-21
 Identities = 102/369 (27%), Positives = 147/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W + +  I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 3237 YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 3286

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 3287 IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 3339

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +  L D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 3340 PTIRGNKDEAEKLMTLVDT------SINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 3391

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 3392 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 3448

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3506

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 3507 IASNEAGEV 3515



 Score =  104 bits (249), Expect = 9e-21
 Identities = 101/398 (25%), Positives = 164/398 (41%), Gaps = 40/398 (10%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVF 4474
            KM    V      + E +  G P+P+I WY++N  +  S      TF  +  +I I    
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSM---TFLNRGQIIDIESAQ 1982

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + D+ ++  VA N  G  +   +L V           V PS + +   V V     VRL+
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH----------VAPSISGSNNMVAVVVNNPVRLE 2032

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +  G     + WLK+G  V     N +    G   L +  A   D+G+Y CVA+N+AGE
Sbjct: 2033 CEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             + D +  V +                PP I+   ++  V   QA+E  C+    P PT+
Sbjct: 2092 KQRDIDLRVYV----------------PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135

Query: 4655 QWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             W K G  L+K      +S + +   L+I +A  +D G Y C A N AG+      + + 
Sbjct: 2136 TWLKDGHPLLKKP---GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHE 4772
             P    N+     L  + V EG       + +    P + W ++G+ ++ ++     I  
Sbjct: 2193 VP---PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS 2249

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G    L I    + D   ++C A+  AG  +    L V
Sbjct: 2250 GGRQ-LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286



 Score =  102 bits (245), Expect = 3e-20
 Identities = 96/389 (24%), Positives = 155/389 (39%), Gaps = 31/389 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  +   R E E  G P P + W ++  P+ +  +  +   S   IL +    + D+  +
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRY 2081

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G  +   +L V           VPP+     QNV+V   Q V L  +     
Sbjct: 2082 TCVAVNAAGEKQRDIDLRV----------YVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  + WLK+G  +       I E      L I +A  QD+G+Y C A N AG+   +   
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNVAGKTEKNYNV 2189

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             + +P       P    +       + L    V EG  I   C+  G P P + W K   
Sbjct: 2190 NIWVP-------PNIGGS-------DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +      ++   +    L+IS A   D   Y CVA N AG       L+V       N 
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
             +     +I+V  G+    + ++     PT+ W+++G  + +    +++ EG+  +L + 
Sbjct: 2296 GSHPT--EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQLK 2351

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            N +  DTG + C A   AG  +    L V
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380



 Score =  101 bits (243), Expect = 5e-20
 Identities = 101/380 (26%), Positives = 148/380 (38%), Gaps = 35/380 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 1006 GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPGG-EESGEYVCTATNTAGYAKRK 1063

Query: 4496 ANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V  + R    + G+           ++V +G+ V L  +V    P  + W K  + 
Sbjct: 1064 VQLTVYVRPRVFGDQRGLSQDK----PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 1119

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P          G+  + I E    DSG Y CVA N AG      +  V          
Sbjct: 1120 ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV---------- 1167

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S 
Sbjct: 1168 ------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIV 4731
               + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V
Sbjct: 1222 P--DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 1279

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                Q  +F        KPTI+WL  G  L    P   ++ +G   +L+I +    D G 
Sbjct: 1280 A--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGE 1335

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A   AG  E    L V
Sbjct: 1336 YICVAVNEAGTTERKYNLKV 1355



 Score =  101 bits (241), Expect = 8e-20
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 3912

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 3970

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 3971 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 4013

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 4014 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 4071

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 4072 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 4126 RVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 1242 VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 1293

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 1294 PKPTIKWLHNGRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 1353 LKVH----------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 1400

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 1453

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 1506

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 1507 GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 1561

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 1562 NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 1619

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 1620 VANVAGTAEKS 1630



 Score =  100 bits (239), Expect = 1e-19
 Identities = 106/423 (25%), Positives = 169/423 (39%), Gaps = 31/423 (7%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKK-MQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T +   A  +ER + G      P I  +  ++  +V E +      E  G P+P I W++
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK 2515

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRR 4505
            +  P++   D   H  S    L I  V V  +  +  +A +  G    S +L V      
Sbjct: 2516 DGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
             G G    P      ++V V       L  +     P  + W K+G  ++ +   +IL  
Sbjct: 2574 AGVGSDGNP------EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL-- 2625

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             G  TL IL A   ++G+Y CVA N AGE     E  V +P   +K         +P E+
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL-SPKEV 2684

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
                K K+      +   C+    P  ++ WYK  + +K   +  ++  A+ +TL+I EA
Sbjct: 2685 ----KIKV---NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA--ANGHTLQIKEA 2735

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-------VVYEGQPA 4738
               D G Y CVA N AG   +   + +  P     L  +  + D         V    P 
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +  +   PT+ W ++G   P T   +++      VL I     ED G +TC A   
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNE 2853

Query: 4799 AGQ 4801
            AG+
Sbjct: 2854 AGE 2856



 Score =   99 bits (238), Expect = 2e-19
 Identities = 82/299 (27%), Positives = 123/299 (41%), Gaps = 40/299 (13%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P    +  G     + ++ G P P VTW K+G  LI +   EI+    H  L+++N   S
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGH-ILQLKNIHVS 2356

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            D+G Y  +A N  G       L+V +P  S + + RS                       
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHRS----------------------- 2392

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ + V +   V+        C  +G P P +TWF +   +    + +IL   SG   L 
Sbjct: 2393 PENISVVEKNSVS------LTCEASGIPLPSITWFKDGWPVSLSNSVRIL---SGGRMLR 2443

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +   T+ D+G  TCV RN +GE      L+V+    +V    +E    + V+E + V L 
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE---DVKVKEKQSVTLT 2500

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG P+    +   H   G   L I   +      Y C A + AG
Sbjct: 2501 CEVTGNPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 35/375 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E E  G P P + W ++  P+  +   +I       IL ++ + V D+  +  VA N  G
Sbjct: 2313 ECEVQGIPPPTVTWMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT---LTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
                  +L V            PPS      + +N++V     V L  + +G     + W
Sbjct: 2371 MTDKKYDLSVH----------APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITW 2420

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G  V   + N +    G   L +++   +D+G+Y CV  N+AGE R      V +P 
Sbjct: 2421 FKDGWPVS--LSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP- 2477

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                  P     N        L+D  V E Q++  +C++ G P+P + W+K  + ++  +
Sbjct: 2478 ------PHIVGENT-------LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               +   +    L+I+       G Y C+A + AG  + +  L V        + +    
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
             D+ V    P     +  S    TI W ++G  +    + +++  G    +L  N  E++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL--NAQEDN 2640

Query: 4788 TGTFTCRATTAAGQV 4802
             G ++C AT  AG++
Sbjct: 2641 AGRYSCVATNEAGEM 2655



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 95/380 (25%), Positives = 157/380 (41%), Gaps = 34/380 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E +  P P + WY++  P+ +S    I       +L I +  VED+  +  VA N  G  
Sbjct: 2800 ETNAAPPPTLTWYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857

Query: 4493 KCSANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                ++ V+     +G    +P       + V V   +   ++   +G+      W K+G
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLP-------EEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2910

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            + +  D  +K L       L IL     D G+Y CVA N+AG A+               
Sbjct: 2911 QPLLEDDHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAK--------------- 2953

Query: 4612 PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             K      + PP +I P  + + V     I  +C++ G P P + W K ++ IK +    
Sbjct: 2954 -KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +       TL+I  A   D G+Y C+A N AG       L V  P    +  + + L  +
Sbjct: 3013 I--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-LSVV 3069

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG     + +  +   P I W + G +I E+   +++ +G   +L I      DTG 
Sbjct: 3070 NVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQ 3127

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + CRA   AG+ + +  L V
Sbjct: 3128 YVCRAINVAGRDDKNFHLNV 3147



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 88/301 (29%), Positives = 127/301 (42%), Gaps = 37/301 (12%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 1051

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 1052 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 1090

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 1091 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 1143

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 579  Y 579
            +
Sbjct: 1257 H 1257



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF 4137

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 4138 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 4184

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 4185 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 4241

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 4242 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 4286 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKAIG 4341

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 4394

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 4395 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 88/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 1227

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 1268

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 1269 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 1318

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
             G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ + ++V  
Sbjct: 1319 DGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVTNVSVLL 1374

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 1375 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCK 1432

Query: 565  AQNVAGST 572
            A N+AG++
Sbjct: 1433 AINIAGTS 1440



 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 96/388 (24%), Positives = 160/388 (41%), Gaps = 36/388 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E        E  G PLP I W+++ +P+  S   +I   S   +L + Q  +ED+  +
Sbjct: 2398 VVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRMLRLMQTTMEDAGQY 2455

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTG 4539
              V  N  G          EE++  G   +VPP      T ++V V   Q V L  +VTG
Sbjct: 2456 TCVVRNAAG----------EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                ++ W K+G+ +Q D  + I+   G   L I       +G+Y C+A + AG      
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
               V +      P      ++  PE      D  V         C+    P  T+ W+K 
Sbjct: 2564 SLNVFV-----SPTIAGVGSDGNPE------DVTVILNSPTSLVCEAYSYPPATITWFKD 2612

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP---D 4716
               ++ ++  ++       TL+I  A  ++ G Y CVA N AG +    ++KV  P   +
Sbjct: 2613 GTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2670

Query: 4717 QADNL-PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
            + D   P L+P +++ +        + +  +    ++ W ++G   P   D  +    N 
Sbjct: 2671 KGDLWGPGLSP-KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ--PLKSDDHVNIAANG 2727

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              L I      DTG +TC A+  AG+ E
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDE 2755



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 64/209 (30%), Positives = 88/209 (42%), Gaps = 8/209 (3%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYP 421
            +   QY    +    EER       L P  +      +D  V E +     C VTG P P
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            E+TW  + + +++D  H I+   SG   L ITNV +  +G  TC+A + +G  +    LN
Sbjct: 2510 EITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V     +           + V    P  L   A   P   ITW KDG P+  N  +RI  
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2626

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G  TL I  A+  +A  Y C A N AG
Sbjct: 2627 --GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 3896

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 3951

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 4006

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 4007 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 4065 GTALGKIKL 4073



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 99/397 (24%), Positives = 159/397 (40%), Gaps = 41/397 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N  V  
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1934

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+ + +        L       + I  A   D+G Y+CV
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1992

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1993 AINSAGA----TELFYSL------------QVHVAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++ A   D G Y CVA N+AG    
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 2095 DIDLRVYVPPN-----IMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              +    N +VL I +   +DTG +TC AT  AG+ E
Sbjct: 2150 LSI--SENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 96/379 (25%), Positives = 156/379 (41%), Gaps = 42/379 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W   +  I  S  +++ +  T   L I+    +D+ ++  +A N  GT K +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            + L   E           P   +    + V  G +  ++ K +G  P  V W K   +++
Sbjct: 694  STLRYIEA----------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P   +  L  D    LL I E    D+G Y CVAIN AG A                   
Sbjct: 744  P---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI--------------- 785

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             T    +PP  I+   D  +  G  +   C + G P PT++W + D +   S+ F +S  
Sbjct: 786  -TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 4675 ADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +   T  L I   +  D+G Y C A N  G+  + ++  VT       L  ++P    V+
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK--IQSETTVTVTGLVAPLIGISPSVANVI 902

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQ      T +     P  +W++  A++ + P   +  +G+   L I     +D G +
Sbjct: 903  -EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEY 958

Query: 4792 TCRATTAAGQVETSAKLVV 4810
            TC A+  AG    +  +VV
Sbjct: 959  TCVASNVAGTNNKTTSVVV 977



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 86/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ +  G     + W 
Sbjct: 1533 KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY 1582

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 1583 KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 1638

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   CK  G P P + W K    +K +  
Sbjct: 1639 -----PMIEG-----NLATPLNKQVVI-AHSLTLECKAAGNPSPILTWLKDGVPVKANDN 1687

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             ++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 1688 IRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 1742

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G LI E   F+++  G    L+I      +T
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNT 1800

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTV 1822



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V+G P P+++W  N++ I+ + N  I+    G   L I    +SD G  TC+A N++G
Sbjct: 2986 CEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 3043 ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3101

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 3102 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 3137



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 87/367 (23%), Positives = 146/367 (39%), Gaps = 17/367 (4%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W+++  P++++ + +I        L I     +++  ++ VA N  G       
Sbjct: 2603 PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V       +G +  P   L+ + V +     + L+ +        + W K+G+ ++ D
Sbjct: 2661 VKVYIPPIINKGDLWGPG--LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2718

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                I      +TL I EA   D+G+Y CVA N AGE   D +  + +P +  K      
Sbjct: 2719 DHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
              +         KD I+     I   C+    P PT+ WYK G  L    K   +     
Sbjct: 2777 MLDTGRN--GEAKDVII--NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PG 2829

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L+I  A  ED G Y CVA N AG  ++   ++V  P       +  P  ++ V   +
Sbjct: 2830 GRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP-EEVTVLVNK 2888

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  +   +    P   W ++G  + E    + +   N  +L I NT   D G + C A 
Sbjct: 2889 SALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRILQILNTQITDIGRYVCVAE 2946

Query: 4797 TAAGQVE 4803
              AG  +
Sbjct: 2947 NTAGSAK 2953



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 3607

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 3608 -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 3661

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 3662 LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 3712

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 3713 PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 3762

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 3763 LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 3815

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 3816 IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 3875

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 3876 CTVTNGAGDDKRTVDLTVQ 3894



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 3553 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 3602

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 3603 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 3640

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
              +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 3641 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 3696

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 3697 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 3752 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 4064

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 4065 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 4119

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 4120 VESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 1835 ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 1892

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 1893 AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1947

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1948 PVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 2000



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 13/217 (5%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
            R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  + + I +    KIL+N      L+I    +S++G+  C+A N +G+   +  + V 
Sbjct: 1767 MWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTD 542
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I + 
Sbjct: 1824 VPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSS 1879

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 1880 G--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 49/290 (16%)

Query: 293  PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGY 352
            P   +TWFK+G  L ++    I+      TL++ N Q+ ++G Y+ +A N  G ++    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            + V  P                       + ++    L+P+ VK+  +  +T       +
Sbjct: 2661 VKVYIPP-------------------IINKGDLWGPGLSPKEVKIKVNNTLT------LE 2695

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C     P   ++W+ + + ++ D +  I  N    H L I    +SD+G  TCVA N +G
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAG 2752

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNV----REGE--------PVVLNARAVGTPTP 520
            E      +N+      V P F + +   N+    R GE        P+ L       P P
Sbjct: 2753 EDELDFDVNI-----QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2807

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +TW KDG P+  + ++ I    G   L IPRAK  DA  Y C A N AG
Sbjct: 2808 TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAG 2855



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 52/350 (14%)

Query: 229 RLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGAD 282
           R L  +S   +S+     GE    +S+E   S   V      PPK+   P+N     G++
Sbjct: 569 RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSE 628

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
                  +G P+P++ W  N   ++ S+++ + +     TL ++N    D+G Y      
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY------ 679

Query: 343 PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
             GC+ ++      + T+              +Q  T   IE      AP+ + V  +  
Sbjct: 680 --GCLASNS-----AGTD--------------KQNSTLRYIE------APKLMVVQSELL 712

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L I      D+G 
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGD 769

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TCVA N++G    +  L+V        P F++  + +++  G  V L     G P P I
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI 824

Query: 523 TWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            W++ D +PI   P  +   +      L I    ASD   Y C A+N  G
Sbjct: 825 KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFG 874



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/302 (24%), Positives = 132/302 (43%), Gaps = 33/302 (10%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P+  K++       + +    P   ++W+K+GQ L  S+ H  I  + HT L+++  Q S
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANGHT-LQIKEAQIS 2738

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR--ETEERIEISEKA 389
            D+G YT        C+ ++  +A E   +  V  Q    +  + Q+  E    ++     
Sbjct: 2739 DTGRYT--------CVASN--IAGEDELDFDVNIQ----VPPSFQKLWEIGNMLDTGRNG 2784

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
             A         +DV         C     P P +TW+ +   +    + K+L+   G   
Sbjct: 2785 EA---------KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS--SDKVLILPGGR-V 2832

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I    + D+G  TCVA N++GE + Q  + V+    ++     +    + V   +  +
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSAL 2891

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +   + G+P PR +WQKDG P++ +   +  ++G    L I   + +D   Y C A+N A
Sbjct: 2892 IECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNG--RILQILNTQITDIGRYVCVAENTA 2949

Query: 570  GS 571
            GS
Sbjct: 2950 GS 2951



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/311 (23%), Positives = 128/311 (41%), Gaps = 40/311 (12%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 3304 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 3348

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               +EK +         D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 3349 ---AEKLMT------LVDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLL- 3392

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 3393 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 3448

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 3449 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 3505

Query: 563  CTAQNVAGSTA 573
            C A N AG  +
Sbjct: 3506 CIASNEAGEVS 3516



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 3625 TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 3682

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 3683 DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 3732

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 3790

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 3791 TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 3895 VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 3950 GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 3984



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 3769

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 3819

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 3880 NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 3923

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 3980

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 3981 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4035

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 4036 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 9/163 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 2030 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSAQISDTGRYTCVAVN 2087

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 2088 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 2142

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P++  P L I  +   S L I  A+  D   Y C A NVAG T
Sbjct: 2143 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKT 2183



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 722  ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 779

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 780  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 829

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 830  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 885

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 886  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 936  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 986

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 987  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPGGE 1044

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 60/204 (29%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 380  EERIEISEKALAPQFVK-----VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            E+ ++   + L P  +K     + ++  V   K    +C  +G P P  +W  + + + +
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
            D +HK L N      L I N  ++D G   CVA N +G       LNV     V+ PK  
Sbjct: 2916 DDHHKFLSN---GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-- 2970

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
                 L V     + L     G P P ++W K+  PI  N    I    G  TL I RAK
Sbjct: 2971 --SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAK 3026

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD   Y C A N AG +  +  L
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSL 3050



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 101/475 (21%), Positives = 177/475 (37%), Gaps = 49/475 (10%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W +   P V   + +++  + +G V  + K +   D G YTC A N  GE  
Sbjct: 1852 GIPNPSITWLKDDQP-VNTAQGNLKI-QSSGRVLQIAKTLLE-DAGRYTCVATNAAGETQ 1908

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              + +                    VS  V+ +           +        +  T  +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
              +  ++   E   + +    + +     G      +TE+  SL     P I+       
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAG------ATELFYSLQVHVAPSISGSNNMVA 2022

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +      + + +  G P P +TW K+G   ++S  + +        L + + Q SD+G Y
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSP-VSSFSNGLQVLSGGRILALTSAQISDTGRY 2081

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T        C+      AV +  E              +QR+ + R+ +    +  +   
Sbjct: 2082 T--------CV------AVNAAGE--------------KQRDIDLRVYVPPNIMGEE--- 2110

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              Q+  V   +     C+    P P +TW  +   +       I  N S    L I +  
Sbjct: 2111 --QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---VLKIEDAQ 2165

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            + D+G  TC A N +G+T     +N+     +      +  + L V EG  + L   + G
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGS---DELTQLTVIEGNLISLLCESSG 2222

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             P P + W+K G P++ +   R+    G   L I  A+ SDAA Y C A NVAG+
Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 3503

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 3560

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 3561 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
            P  V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 1460 PNEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 1510

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 1567

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 1568 ECETRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 1625

Query: 571  S 571
            +
Sbjct: 1626 T 1626



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/281 (24%), Positives = 114/281 (40%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 1851 NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 1901

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 1902 NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1938

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+ ++R +    +   L   +    + I +  +SD+G+  CVA N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQIIDIESAQISDAGIYKCVAIN 1995

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1996 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +  A+ SD   Y C A N AG
Sbjct: 2051 P-VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 2090



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 13/177 (7%)

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            V  D  V    + + +C   G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 1553 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 1609

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
            +SDS   TC   N +G       ++V      V P      +T LN  V     + L  +
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECK 1664

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P+P +TW KDGVP+  N  +RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 12/168 (7%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 4236

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G
Sbjct: 4292 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 4315

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K    + V+E          PP F     +  +    G
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE----------PPVFKGDYPSNWIEPLGG 4365

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 4366 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 4421

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 4422 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 4464

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 4465 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 4520



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 52/187 (27%), Positives = 81/187 (43%), Gaps = 11/187 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+   + +++  T G      C  TG P P++ W +ND  I   + +++    + +  L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM----TSDGTLF 667

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V+ 
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVME 722

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N AG 
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGR 780

Query: 572 TATRARL 578
              +  L
Sbjct: 781 ATGKITL 787



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
            L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 1307 LTGREPGISILEDGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 1363

Query: 398  CQ---DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
             +   +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GKILKLFR 1420

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
             T  D+G  +C A N +G +     ++V+    ++   F    S +  R+   V L  + 
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD---VALECQV 1477

Query: 515  VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 1533

Query: 572  TATRARL 578
             A   +L
Sbjct: 1534 QAKDIKL 1540



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 909

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 966

Query: 570 GS 571
           G+
Sbjct: 967 GT 968



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 4426 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 4480

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 4481 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 4521



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG +    C  +G P P + W      +  D   ++ +  SG   L I+    SD+ +
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL-SGGRQLQISIAEKSDAAL 2266

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             +CVA N +G    +  L V  +  +         + + V  G+ + L     G P P +
Sbjct: 2267 YSCVASNVAGTAKKEYNLQVYIRPTIT--NSGSHPTEIIVTRGKSISLECEVQGIPPPTV 2324

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            TW KDG P+I    + I  +G    L +     SD   Y C A NVAG T
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAVNVAGMT 2372



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 4314

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G   F   +  +  ++   P F   + +  +   G   +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG---FVKAIGFVYVKE--PPVFKGDYPSNWIEPLGGNAIL 4369

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/345 (22%), Positives = 130/345 (37%), Gaps = 37/345 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I +V + D   +  +A +  GT +      V E          PP       NV VT 
Sbjct: 484  LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE----------PPPVIQVPNNVTVTP 533

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L   +      ++ W +N + V+     +I       +L +      D+G+Y C+
Sbjct: 534  GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCM 592

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              +  G +       V                  PP++    K++    G  +   C   
Sbjct: 593  VSSEGGSSAASVFLTVQ----------------EPPKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P P + W   D  I  S  ++M  T+D  TL I  A P+D G Y C+A NSAG     
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRM--TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            + L+  +  +      +    +++V  G     + + +    P ++W +    +   P  
Sbjct: 694  STLRYIEAPK-----LMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPST 746

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +I +    +L I  T + D G +TC A   AG+      L V S
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D  V     T   C     P   +TWF +   +  + N +IL    G   L I N    
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQED 2639

Query: 459  DSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            ++G  +CVA N++GE      + V     I K  +  P    +   + ++    + L   
Sbjct: 2640 NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE 2697

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   P+  ++W KDG P+  +  + I  +G   TL I  A+ SD   Y C A N+AG
Sbjct: 2698 AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAG 2752



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 3762 ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 3876

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 3877 TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 3932 KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 74/294 (25%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            +G+         G P P + W ++GQ L   + H  ++TH    L++   +  DSG YT 
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG-MVLQLLKAETEDSGKYTC 3506

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            +A N  G +     L V  P           +I  +++ E     EIS     P     C
Sbjct: 3507 IASNEAGEVSKHFILKVLEP----------PHINGSEEHE-----EISVIVNNP-LELTC 3550

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                +   KMT       GRP P+        Q++            G   L I+   + 
Sbjct: 3551 IASGIPAPKMTWMK---DGRPLPQTD------QVQ---------TLGGGEVLRISTAQVE 3592

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G  TC+A + +G+   +  + V     +         + L  R+   V L  ++   P
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ---VTLECKSDAVP 3649

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P ITW ++G  +   P +RI +  G   L I  A   D A Y C A N+AG T
Sbjct: 3650 PPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGKT 3701



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L I  V   D+G  TC+
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQIAFVQPGDAGHYTCM 4149

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 4150 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4204

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 4205 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 61/277 (22%), Positives = 112/277 (40%), Gaps = 28/277 (10%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            ++   V    P  + +++NG  +  D   + L+E  +  L I +    D G YEC+A++S
Sbjct: 448  QIPCSVDSLLPFTLSFVRNGVTLGVD---QYLKESASVNLDIAKVTLSDEGFYECIAVSS 504

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG  R      VS                 PP +I+   +  V  G+    +C I+    
Sbjct: 505  AGTGRAQTFFDVS----------------EPPPVIQVPNNVTVTPGERAVLTCLIISAVD 548

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
              + W + D+ ++ ++  ++ RT    +L +      D G+Y C+  +  G    +  L 
Sbjct: 549  YNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            V +P +   +P     ++     G         T   KP I W      I  +  ++M  
Sbjct: 608  VQEPPKVTVMP-----KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            +G    L I N   +D G + C A+ +AG  + ++ L
Sbjct: 663  DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 12/201 (5%)

Query: 402  DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
            +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 955

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 956  GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 1010

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             + W K G  +I     +  + G   +L +      ++  Y CTA N AG    + +L  
Sbjct: 1011 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068

Query: 581  XXXXXXXXXQKRLHLPRPTKV 601
                     Q+ L   +P ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEI 1089



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 12/188 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++V  +  VT G+     C +       +TW  NDR +R        +    N +L 
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVL 510
           + +V  +D+G   C+  ++ G +A    L V E  +V V PK        +   G  V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK------NQSFTGGSEVSI 631

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P+I W  + + I+ +   R+ +DG   TL I  A   DA  Y C A N AG
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688

Query: 571 STATRARL 578
           +    + L
Sbjct: 689 TDKQNSTL 696



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N+ G+++    L   
Sbjct: 2996 LSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   EC    V  P   I WY NG+ +  ST ++ 
Sbjct: 3054 VPPSIKDHDSESLSVVNV---REGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEI 3108

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 3109 LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 104/477 (21%), Positives = 174/477 (36%), Gaps = 55/477 (11%)

Query: 99   PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            P P ++W +   PL   +K  +      G   L I +    D G YTC A N+ GE    
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLIL----PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860

Query: 159  ----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                V + P                 + S  +E  + G+        +  Q +   +   
Sbjct: 2861 YDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--H 2918

Query: 215  HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
            H    + ++       + ++     + +   G +    +  +      V P  I  K  N
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-----VPPSVIGPKSEN 2973

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
              +          ++SG P P ++W KN Q  I  N + +I      TL++   + SD G
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQP-IKLNTNTLIVPGGR-TLQIIRAKVSDGG 3031

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERIEISEKALAPQ 393
             YT +A N  G       L V  P    ++D  S+ ++    RE T   +E    A+ P 
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSLECESNAVPPP 3089

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
             +   ++     G+M      +T   + E+   + D Q+   +  K  V+++G +     
Sbjct: 3090 VITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVSDTGQYVCRAI 3133

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV               +G       LNV     +  P+      T++     PV L   
Sbjct: 3134 NV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS----NPVTLTCD 3174

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C A N+ G
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 4432 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 4482

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 4483 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 4531



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C+  G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 1718

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  I
Sbjct: 1719 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 1776 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 1812



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 1238

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
             TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 1239 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 1296

Query: 521  RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W  +G  +    P + I  DG  + L I      D   Y C A N AG+T  +  L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 14/157 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA----EISVK 3137
            I WF +G  +E++  IR +   G   L+IL  +  ++G YSC ATN+ G+     E+ V 
Sbjct: 2607 ITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVY 2664

Query: 3138 L-ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +   ++K     P  +   + ++ +K   +   EC    +  P   + WY +GQP++   
Sbjct: 2665 IPPIINKGDLWGPGLSP--KEVK-IKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDD 2719

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +   ++ G   L I   Q  D+G Y C A N  GED
Sbjct: 2720 HVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGED 2754



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 62/288 (21%), Positives = 104/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 4132

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 4133 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4192

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 4193 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 4250

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 4251 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 4303

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +   G++ V+ P
Sbjct: 4304 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 3515

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 3516 SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3569

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 3570 PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 3608



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +  S  IR + A G V+  I+  + +D   Y+C A+N+ G    
Sbjct: 3367 TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYTCVASNRAGVDNK 3424

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L+            T  I  ++    G S    C       P M   W  +GQP+  
Sbjct: 3425 HYNLQVFAPPNMDNSMGTEEITVLK----GSSTSMACITDGTPAPSM--AWLRDGQPLGL 3478

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + TVS  G +VL +   +  DSG+Y C A N+ GE
Sbjct: 3479 DAHL-TVSTHG-MVLQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 17/203 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +L+IL T+ TD G Y C A N  G A+   ++ +       G K    T + N       
Sbjct: 2927 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN------- 2979

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                  C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C
Sbjct: 2980 NFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTC 3035

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----E 3280
             A N+ GE   + ++  Y    +     +  S+  +RE  S+    +     P      +
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3095

Query: 3281 PPKFITQIQDVTKLVEGQSAHFE 3303
              + IT+   V  L +GQ  H +
Sbjct: 3096 NGRMITESTHVEILADGQMLHIK 3118



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 64/257 (24%), Positives = 98/257 (38%), Gaps = 22/257 (8%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P + W +K +P++  +   +R    +G   L I      D   Y+C A N  G A 
Sbjct: 2222 GIPPPNLIWKKKGSPVLTDSMGRVRI--LSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279

Query: 157  ----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
                  VYI+P                R  S ++E +  G    T    +    +    G
Sbjct: 2280 KEYNLQVYIRPT-ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG 2338

Query: 213  TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES-DVQISTEIDRSLGPVSPPKIA-- 269
             +            E  +L+  +   S T RYV  + +V   T+    L   +PP I   
Sbjct: 2339 VEILD---------EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389

Query: 270  -QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             + P N  + E        + SG P P +TWFK+G  +  SN   I++      LR+  T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQT 2447

Query: 329  QKSDSGHYTLLAENPNG 345
               D+G YT +  N  G
Sbjct: 2448 TMEDAGQYTCVVRNAAG 2464



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 3728 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 3784

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 3785 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 3883



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           + ES +  L I  VTLSD G   C+A + +G    Q   +V E      P  ++  + + 
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE-----PPPVIQVPNNVT 530

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V  GE  VL    +      +TWQ++   +      RI T    S L++   K +DA  Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEY 589

Query: 562 QCTAQNVAGSTA 573
            C   +  GS+A
Sbjct: 590 HCMVSSEGGSSA 601



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 260  LGPVSPPKIAQKP--RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            L  + PP I  +    + K++E        +++GNP P +TW K+GQ L     H II+ 
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS- 2530

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L++ N Q   +G YT LA +P G
Sbjct: 2531 -GGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 86/218 (39%), Gaps = 35/218 (16%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            ++ IK       E     I  ++L   W KDG+P+++   +    N G+  L IK   + 
Sbjct: 2683 EVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQIS 2738

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEV 1037
            D G YTC A N  G+     ++ I          Q P   +K+  + +     +  E + 
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI----------QVPPSFQKLWEIGNMLDTGRNGEAKD 2788

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD 1097
             I   P                S + E    P   LT    WY +G  +TS++++     
Sbjct: 2789 VIINNP---------------ISLYCETNAAPPPTLT----WYKDGHPLTSSDKVLILP- 2828

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G   L I   + ED+G YT VA N AGE  L   + V
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 74/293 (25%), Positives = 118/293 (40%), Gaps = 46/293 (15%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   + WY +G+ L+      + ++ G  TL + +    D+G YTC A N  GE      
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGEDELDFD 2759

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            V            Q P   + L +I N+ D             TGR  E     KD++ I
Sbjct: 2760 V----------NIQVPPSFQKLWEIGNMLD-------------TGRNGEA----KDVI-I 2791

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +     + E +  P       + W+ +G  + +S ++  +   G  VL+I   K  D+G 
Sbjct: 2792 NNPISLYCETNAAPPP----TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGR 2845

Query: 3121 YSCRATNKWGQ--AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            Y+C A N+ G+   +  V++      KG        +  +      +SA  EC  +    
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLV----NKSALIEC--LSSGS 2899

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P  +  W  +GQP+      K +S+    +L I  TQ  D G YVC A N  G
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAG 2950



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 66/168 (39%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 4012 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4069

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 4070 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 4121

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L IA+ Q  D+G Y C A N  G   T   +  +
Sbjct: 4122 SIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 3236 YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 3287

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 3288 ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 4431

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG P+T+S ++  I   G V L I   + EDAG YT  AVN+ GE      
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVL-ILPGGRV-LQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862

Query: 860  IRVAARSTVT-ADLGIPEQ 877
            +RV     +  A+  +PE+
Sbjct: 2863 VRVLVPPIIKGANSDLPEE 2881



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   N   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 4404

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 4405 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 1311

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 1312 PGISILEDG-TLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            ++   EC++  +  P   V W  +G PL+ K +   I D G++ +    ++  D+G Y+C
Sbjct: 2308 KSISLECEVQGIPPPT--VTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSDTGRYVC 2363

Query: 4049 RATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
             A N+ GM + K  +     P I+ + + P+++  +EK
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 4194 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 4250 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 4300

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V     I        P      P N  
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWI 4360

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 4361 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 4417

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 2104 PNIMGEEQN 2112



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 18/164 (10%)

Query: 3079 SMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            S  + W+ +G+ +++   +  + A G   L+I   + +D+G Y+C A+N  G+ E+   +
Sbjct: 2703 SASLSWYKDGQPLKSDDHVN-IAANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV--PVD-------DPDMKIEWYHNG 3189
                    QK      I N+  L  G++   +  ++  P+         P   + WY +G
Sbjct: 2761 NIQVPPSFQK---LWEIGNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG 2815

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+  S ++  +   G  VL I   +  D+G Y C A N+ GED
Sbjct: 2816 HPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 3255 DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 3312

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            D+G YTC ATN  GE      L V     +     +    EK+  L DTS
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTI---RGNKDEAEKLMTLVDTS 3359



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  +  N     GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 4402

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  N   I  SHR R   + G + ++    K  D+G Y C A+N  G  + 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQ 692

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            +  L  ++  K         +Q+   +  G     EC    +  P +K  W+     +R 
Sbjct: 693  NSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGIPPPQVK--WFKGDLELRP 744

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLE 3250
            ST +  + D    +L I  TQ+ D+G+Y C A N+ G    + T++  G   V+++
Sbjct: 745  STFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD-VGSPPVFIQ 797



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 1170 PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 1268

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 1269 ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 1308

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 1309 GREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 1368 TNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 4078 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 4131

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 15/197 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP    V  ++  ++ G+ A     +I   D ++   W  N + +  +   R +  
Sbjct: 515  DVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLT--WQRNDRDVRLAEPAR-IRT 570

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               + LE+   K  D+G Y C  +++ G +  SV L        Q+P   T +   +   
Sbjct: 571  LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV------QEPPKVTVMPKNQSFT 624

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G      C+      P  KI W  N   +  S R +  SD    + + A     D+G Y
Sbjct: 625  GGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAA---PKDAGIY 679

Query: 3223 VCRAYNKYGEDFTRATI 3239
             C A N  G D   +T+
Sbjct: 680  GCLASNSAGTDKQNSTL 696



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PP    +P   +   G      C  TG+PKP++ W +N   IV   RY++T DG
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 4489 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 4544

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 4545 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGK 875



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 756  LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 809

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 810  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 870  ENQFGKIQSETTVTVTG 886



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 789  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 849  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 1371 SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDA 1426

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST-QNEAG--LEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +   NE    L +   LE + K      + 
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 1486

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 1487 WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C        A+T    G  I+ S +++Y++      
Sbjct: 1546 PSIKGGNVTTDI-SVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 1604

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 1605 IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++ +    + G   L +      D G Y C A +  GE
Sbjct: 1664 KAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV      +L++      D+G YSC+A N  G ++  
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVN--NGKILKLFRATPEDAGRYSCKAINIAGTSQKY 1443

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +           T+  N   +   +    EC V     PD  I W+ +G+P+   
Sbjct: 1444 FNIDVL----VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLG 1497

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 1498 DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +    G  I  E  ++ +  PT  + W+K+G  +   ++   I   G+I L + ++++ D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSD 2357

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
            +G Y C AV+  G+ + K  L V    +I    + PE +  +++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 35/210 (16%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++++  N     E     +  P   + W ++G P+++ + +    + G+  L +K    
Sbjct: 2682 KEVKIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQI 2737

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G YTC A N  GE      + +Q   S Q        L +I  + D+ R    +DV 
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ-------KLWEIGNMLDTGRNGEAKDVI 2790

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +            N P  L         C     P P +   WY +G  L S  +     
Sbjct: 2791 I------------NNPISL--------YCETNAAPPPTL--TWYKDGHPLTSSDKVLILP 2828

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
              G   L I     ED+G YTC A+N  G+
Sbjct: 2829 --GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 57/266 (21%), Positives = 102/266 (38%), Gaps = 11/266 (4%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            L GNP P   W +  A L++    ++R      D SL I+++   D GEYTC A N  G 
Sbjct: 914  LAGNPIPERRWIKNSAMLLQNPYITVR-----SDGSLHIERVQLQDGGEYTCVASNVAGT 968

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               +  +                    +  T+  KA G    +   S++ + ++ ++   
Sbjct: 969  NNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF 1028

Query: 215  HSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
             +  D    V +       E     + T  Y  +  VQ++  +   +          KP 
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYA-KRKVQLTVYVRPRVFGDQRGLSQDKPV 1087

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSD 332
               +  G +     ++   P P +TW K  Q +   S +H  + + +   +++  T+ SD
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSD 1144

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESP 358
            SG Y  +A N  G +  +  L V  P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVP 1170



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 3652 VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 3710 NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 3759

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 3760 YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 3801



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 3952

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 3996



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +G  +  S+ +R +   G  +L ++ T   D+G Y+C   N  G+      L  +
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P        +E +K  +      T     +P  +I W+ +GQP++       +
Sbjct: 2476 ------VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII 2529

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S   F  L I   Q   +G Y C A +  G      ++N +
Sbjct: 2530 SGGRF--LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2568



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  EC+   V      + W+KNG+ +T       + D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHL 3145



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 3299

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+  L 
Sbjct: 3300 NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTLV 3356

Query: 1960 DDS 1962
            D S
Sbjct: 3357 DTS 3359



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 4252 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 4306

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 4307 VN--GHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     S+ +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 4400

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     ED+G YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1385 CQATNQLGEAVTSCALRVIAKKDLILE 1411
            C ATN+ G    S +L + +   + LE
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 4364 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 4419 CVATNEAGVVERSMSLTLQS 4438



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    + KN  F  G          G P P ++WT     +V  ++Y M     T D +
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM-----TSDGT 665

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L IK   P D G Y C A N  G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAG 688



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I +  G     E  ++ I   T  V W+KDG P+  +  +    + G++ L +K++ V 
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI-LQLKNIHVS 2356

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            D G Y C A N  G      +L++     II   + P  +  ++
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G  +L I  V   DAGHYTC A N  G ++TS  LT+
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 1252 TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 1305

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 1306 ELTGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPII 1392



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 3676

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++ N    D+ +YT +A N  G       L V  P
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 3712



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 4429 ERSMSLTLQSPPIITLE 4445



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 20/170 (11%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDI---------IDESVTIKPRFVTRPKSIE 1454
            AK   IL+  H   L+ I ++ DT RY    +          D SV   P  +   +S E
Sbjct: 2336 AKGVEILDEGHILQLKNI-HVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE 2394

Query: 1455 N--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            N  V+E   V   C+   +   +  + WFK+G PV++ +  R +   G   L ++    E
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPS--ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTME 2450

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            D+G YTC   N  G +     L+      IV     E  LE ++V E +S
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLVPPHIV----GENTLEDVKVKEKQS 2496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632  RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 3429 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 3485

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
              G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 3486 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 3518

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 3519 FILKVLEPPHINGSEEHE 3536



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 3605 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 3655

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 3656 LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 3700



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 3766

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 3767 F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 12/174 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C ATN  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 1188

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 1189 DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 1244

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P
Sbjct: 1245 NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKP 1296



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 1579 ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 1635

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +  I+  
Sbjct: 1636 YVPPMIEGNLATPLN--KQVVIAHSLTLECKA--AGNPSPILTWLKDGVPVKANDNIRI- 1690

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 1691 -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG PV  S+ +      G   L +   T+ DAG YTC   NA G+      L+++
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 1003 TKKDIIAES 1011
                I+ E+
Sbjct: 2476 VPPHIVGEN 2484



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 3257 SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++  L D S
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTLVDTS 3359



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 1216

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 1217 HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 1256



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T   ++ S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 1496

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 1497 GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I V  G  +  +C V+ +  PT  + W  +G P      V  L++ G I L +  I+  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GHI-LQLKNIHVSD 2357

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
             G Y C A N  G       ++  A   I+   + P+ +S
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS 2397



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 3261 GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 3319 CVATNPAG 3326



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 4131

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 4132 --SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P+ +    N     G+ V + C     G    ++ W  N   I   HR+R   +
Sbjct: 606  LTVQEPPKVTVMPKNQSFTGGSEVSIMC--SATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI-AKKDLILESQHPSGLEKIQY 1423
                 L + +  P+D+G+Y C A+N  G    +  LR I A K ++++S+    L  I  
Sbjct: 664  G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITV 720

Query: 1424 LE 1425
            +E
Sbjct: 721  ME 722



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 714 ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 769

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 770 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 826

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 881

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 938

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAG 967



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 1351 YNLKVHVPPVIKDKEQ-------VTNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 1400

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 1401 VTESSTIQTVNN--GKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+  IR + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 1725 YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLIDE 1777

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 1778 RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 1813



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEK 2092

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 2093 QRDIDLRV 2100



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 633  VYPPPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V+ PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTN--TLIVP 3015

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            G  +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   V  EC  E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 3071 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 3127 QYVCRAINVAGRD 3139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LEC    +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 4433 SLTLQS 4438



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 860  IRVAARSTVTADLGIPEQRRYI 881
            + V     +  +L  P  ++ +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVV 1654



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ + + +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 2003

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 2004 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 2053

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +   Q  D+G Y C A N  GE
Sbjct: 2054 SFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVNAAGE 2091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G+ +  EC+++ +      V W K+G P+ I  +   I D G++ L + ++   D+G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSDTG 2359

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             Y C AVN+ G  +    L+  +   I+    N    E I V+E  S
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSII---GNHRSPENISVVEKNS 2403



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G++   E ++  +  PT  V W KDG P+  +  +  I + G++ L + ++   D G Y 
Sbjct: 2307 GKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGV-EILDEGHI-LQLKNIHVSDTGRYV 2362

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
              AVN  G       + V A  ++  +   PE    +EK
Sbjct: 2363 CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   EC     P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 3073 EGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 3302 STLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)

Query: 3047 PPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP  +   K+ ++ + +      EA  +P  D    I W  +G+ I  S R R V + G 
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPD----ITWHKDGRAIVESIRQR-VLSSGS 4132

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LK 3162
              L+I   +  D+G Y+C A N  G +  S KL     +    PR    I++ EG   + 
Sbjct: 4133 --LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL-----TVHVPPR----IRSTEGHYTVN 4181

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +   A   C    +  P   I W  +   + +     T   +G ++L+    +  DSG Y
Sbjct: 4182 ENSQAILPCVADGIPTP--AINWKKDNVLLANLLGKYTAEPYGELILENVVLE--DSGFY 4237

Query: 3223 VCRAYNKYGED 3233
             C A N  GED
Sbjct: 4238 TCVANNAAGED 4248



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 788  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 900

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 901  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 956

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 957  EYTCVASNVAG 967



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 1351 YNLKVHVPP 1359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 84/375 (22%), Positives = 143/375 (38%), Gaps = 32/375 (8%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            +NI V E   V   C  E  G P   I WF +G P +  + V  L+  G   L +     
Sbjct: 2394 ENISVVEKNSVSLTC--EASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTM 2449

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+YTC   N  G       ++      IV E+ L      EK        ++  P  
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E       + + + ++H +    G RF  ++   + P      Y      P+GH+ R+  
Sbjct: 2510 EITWHKDGQPLQEDEAHHI--ISGGRF-LQITNVQVP--HTGRYTCLASSPAGHKSRSFS 2564

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVND------FGEDFTKATISCKKLPDIILQNQVPR- 3935
               FVS  I  V ++ + E +   +N           +  ATI+  K    +  N+  R 
Sbjct: 2565 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI 2624

Query: 3936 --GMKRSEALTQMEATIKKYTSEVYLTEDDL---YDVDKKQPP------RFVTQIQSQTS 3984
              G +  + L   E    +Y+        ++   Y+V    PP       +   +  +  
Sbjct: 2625 LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEV 2684

Query: 3985 LVEMETT-KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
             +++  T   EC+   +  P+  + W+ +G+PL   +    I   G+  +        D+
Sbjct: 2685 KIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVN-IAANGH-TLQIKEAQISDT 2740

Query: 4044 GEYLCRATNLYGMDE 4058
            G Y C A+N+ G DE
Sbjct: 2741 GRYTCVASNIAGEDE 2755



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 4429 ERSMSLTLQS 4438



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 87/402 (21%), Positives = 156/402 (38%), Gaps = 41/402 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 791  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 966

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 967  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 1023

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDQRGLS 1082

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 1137

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +    DSG+Y C A N+ G    + +L       I R  ++
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 1544 IPPSIKGGNVTTDI----SVLINSLIKLECETRGLPMP--AITWYKDGQPIMSSSQALYI 1597

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 1598 -DKG-QYLHIPRAQVSDSATYTCHVANVAG 1625



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 2063

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 2064 GGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V  GK+   EC+V+ +  P   + +  +G  L  A    I  D G++ L +++    D G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTG 2359

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             Y   A+N  G       ++V A  SII   + PE +  + +   +   +   IP P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 3261 GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDT--QNEQAIEQIQLLEDAA 1295
              A N  G        R+   +  VT T   N+   E++  L D +
Sbjct: 3319 CVATNPAGEED-----RIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 3359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S      G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 4399

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL+L+S   +   +   +  S        V + V + P+ +T +      + G      C
Sbjct: 575  SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMC 633

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P  ++ W  N   +   HRYR ++D     L I     +D+G Y C A N+ G
Sbjct: 634  SATGYPKP--KIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 1927 QAVSSIRLN-VQSKESIIRDSQHESALEKIQYLE 1959
                +  L  +++ + ++  S+   AL  I  +E
Sbjct: 689  TDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 897  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 952

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 953  QDGGEYTCVASNVAG 967



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 1224

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
             +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 1225 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 1907

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY + + +
Sbjct: 1908 QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNRLL 1961

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1962 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1998



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +   + +D+G Y+C A N  G+ +  + L   
Sbjct: 2043 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVY 2101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 2102 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 2152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S+    VL I   Q  D+G Y C A N  G+      +N +
Sbjct: 2153 SE-NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 54/211 (25%), Positives = 82/211 (38%), Gaps = 34/211 (16%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            S K V+IK       E     +  A+L   WY + +PLKS        N G   L I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASLS--WYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSA 1702
               D+G YTC         V S IA    +    +  Q   +  +L ++ +     R+  
Sbjct: 2736 QISDTGRYTC---------VASNIA-GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
              +VI   P+           E  AA           P   + W ++G P+ +S+++  +
Sbjct: 2786 AKDVIINNPISLY-------CETNAA-----------PPPTLTWYKDGHPLTSSDKVLIL 2827

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G   L +     ED+G YTC A+NE GE
Sbjct: 2828 P--GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633  VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 3052 VYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTH-VEI 3108

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
               G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 3109 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 3154



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 3126

Query: 842  SYTVRAVNKLG 852
             Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             NL +     I          EK+  L D S
Sbjct: 3332 FNLNVYVTPTIRGNKDE---AEKLMTLVDTS 3359



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS+ I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 4403

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 4404 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 4461

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 4462 QATGEPQPTIT 4472



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 18/270 (6%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 1102 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATNIAG 1157

Query: 154  EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
                +V +                        +   A GT       S+    +   +G 
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 1216

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
             H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 1217 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 1269

Query: 272  PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
            P N+  QE    Q   F     G P+P + W  NG+ L    +  I    + T L + + 
Sbjct: 1270 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEDGTLLVIASV 1328

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               D+G Y  +A N  G       L V  P
Sbjct: 1329 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 22/283 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 1225

Query: 131  LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
            L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 188  H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                A GT        + T K  + NG + +  +       +  LL   S        Y+
Sbjct: 1286 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337

Query: 246  GESDVQI-STEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
              +  +  +TE   +L    PP I  K +  N  +          ++ G P P + W+K+
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 1398 NVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ I+     + +     +V  I   + +++G Y C A N  G    
Sbjct: 1759 TGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKK 1816

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 1817 EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 1865

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 1866 PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 724  AVLHVTPRATIE 735
              LHV    ++E
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQIS--DTGRYTCVAVNAAGEKQR 2094

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 2095 DIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P+++I++   S   EC +  +   +  V W  +G PL+    V+ +++ G  IL++  ++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GH-ILQLKNIH 2354

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
              D G Y C A N  G       L V     II   + P +
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            +L++     +D+G Y C A N  G  +    L      S     R   +I  +E  K+  
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE--KNSV 2404

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   E + +P+      I W+ +G P+  S  ++ +S  G  +L +  T   D+G+Y C 
Sbjct: 2405 SLTCEASGIPLPS----ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCV 2458

Query: 3226 AYNKYGED 3233
              N  GE+
Sbjct: 2459 VRNAAGEE 2466



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 34/215 (15%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+    +   EC  E Y  P+  + WY +G+ L+S      + + G   L I      D+
Sbjct: 2685 KIKVNNTLTLEC--EAYAIPSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDT 2740

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G YTC A N  G+      +N+Q   S          L +I  + D  R   A       
Sbjct: 2741 GRYTCVASNIAGEDELDFDVNIQVPPSF-------QKLWEIGNMLDTGRNGEA------- 2786

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
                         +V   +P+ L         PT+   WY +G P+      K     G 
Sbjct: 2787 ------------KDVIINNPISLYCETNAAPPPTL--TWYKDGHPLTSSD--KVLILPGG 2830

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              L I  A  ED G Y C A N  GE      V+V
Sbjct: 2831 RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 3122

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 3123 SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 3170

Query: 3548 LTPEAESGNPP 3558
            LT +A +G PP
Sbjct: 3171 LTCDA-TGIPP 3180



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 785  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 843

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 844  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 1006 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 1063

Query: 724  AVL--HVTPR 731
              L  +V PR
Sbjct: 1064 VQLTVYVRPR 1073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTV-NNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 860  IRVAARSTV 868
            I V    T+
Sbjct: 1446 IDVLVPPTI 1454



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+  +   +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 1510

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1952 ITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 2010 VAPSISGSN 2018



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            +++  + V   P      + PT++  + G+S   EC ++  P P   V W  +G  L   
Sbjct: 2279 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKA 2336

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                  ++     L +  ++  D+G Y C A+N  G       L+V +  SII    H S
Sbjct: 2337 KGVEILDEGHI--LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII--GNHRS 2392

Query: 1951 ALEKIQYLEDDS 1962
              E I  +E +S
Sbjct: 2393 P-ENISVVEKNS 2403



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +C    V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 3124

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 3125 TGQYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 3126

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626  PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 3661

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 3662 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 3529 EGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS 3588
            EG  + IA     +G   T    +E   PP     P+++ ++    A   C +I   D +
Sbjct: 494  EGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550

Query: 3589 MRVEWFHNGKP--LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            +   W  N +   L   +R++T+ +     LE+  V   DAG Y C  ++  G +  S  
Sbjct: 551  LT--WQRNDRDVRLAEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVF 605

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTE 3670
            L V+    + + P+  S F  G+E
Sbjct: 606  LTVQEPPKVTVMPKNQS-FTGGSE 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PPK     K+ +      V   C       PK +I W  N   +   HRYR   D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGY--PKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              +L I     +D+G Y C A N  G D   +T+   + P +++
Sbjct: 664  -GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 916 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 972

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 973 TSVVVHVLP--TIQHGQQILSTIEGI 996



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P+++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 1446 IDVLVPPTIIG-----TNFPNEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 1496

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 1497 GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 1405 KKDLILESQ-HPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            +K +I ++Q   +GL +         +KK    + +V + P   +   S   V++ + V 
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVA 1845

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
             +C    +   N  + W K+ QPV        I   G V L I   + ED+G YTC A N
Sbjct: 1846 LQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902

Query: 1524 LVGTDEVSCRL 1534
              G  +   +L
Sbjct: 1903 AAGETQQHIQL 1913



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S P   + W+KDG P+ ++  I  +   G  +L I++ + ++AG Y+  A N+ GE I  
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658

Query: 858  ASIRV 862
              ++V
Sbjct: 2659 YEVKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+G  L +   ++     G  TL I + + D++G Y+C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2732 IKI 2734
            +K+
Sbjct: 2661 VKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +C    V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 860  IRVAARSTV 868
            + V    T+
Sbjct: 3334 LNVYVTPTI 3342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 3829 GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 3886

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 3887 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 3945

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 3946 ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 3998

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 4056

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQVP 4078



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 4126

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 4127 VLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 791  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 850  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 994  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 1003 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 1058

Query: 154  EA----ICSVYIQP 163
             A      +VY++P
Sbjct: 1059 YAKRKVQLTVYVRP 1072



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/179 (21%), Positives = 72/179 (40%), Gaps = 7/179 (3%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W   G  +      R     G   L+I   + +D+  YSC A+N  G A+    L+    
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY-- 2287

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             +       +H   I  +  G+S   EC V  +  P   + W  +G P+  +  ++ + D
Sbjct: 2288 IRPTITNSGSHPTEII-VTRGKSISLECEVQGIPPP--TVTWMKDGHPLIKAKGVE-ILD 2343

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
             G  +L +      D+G YVC A N  G    +  ++ +    +      P++++ + +
Sbjct: 2344 EGH-ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E  + P  TI WF +G  + +    R     G   L IL    +++G Y C ATN+ GE 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 2194 VNTCTLKV 2201
            +    +KV
Sbjct: 2656 IKHYEVKV 2663



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIH--FETRIE----PVGDPTMKIEWLKNGQSI 679
            P GEEDR++    ++ P       E  K+    +T I       G P  +I WLKNG  +
Sbjct: 3324 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 3383

Query: 680  EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
              SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 3384 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 3421



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 3728 KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 3784 MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 3795

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 3796 IDLQVHVPP 3804



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 4151 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 4204

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 4205 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 1253 EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 1304

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 1305 RELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 1346



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 1259 QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 1312

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 1313 GISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 1354



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 653  KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            K+  ETR    G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC 
Sbjct: 1566 KLECETR----GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCH 1619

Query: 713  AVSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
              +  G AE    + V     IE     P   Q +
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 1654



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284  QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
            + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 1623

Query: 344  NGCIVTSGYLAVESP 358
             G    S ++ V  P
Sbjct: 1624 AGTAEKSFHVDVYVP 1638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+ + +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 2003

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 2004 YSLQVHVAP 2012



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKDG P+     ++   N     L I+   V D G YTC A N  G+   + N+ I
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ WY +G+ + S + +    + G+  L I   +  D+G YT VA N AGE +L   + +
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            +   S       + L+E          +  M       ++K V +   +NP        I
Sbjct: 2763 QVPPSF------QKLWE----------IGNMLDTGRNGEAKDVII---NNP--------I 2795

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C       PT+   W+ +G  +T  S  K     G   L I  A   D G YT  AV
Sbjct: 2796 SLYCETNAAPPPTL--TWYKDGHPLT--SSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851

Query: 1256 NHLGSAHTSAIVRVI 1270
            N  G       VRV+
Sbjct: 2852 NEAGEDSLQYDVRVL 2866



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 3253 PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 3309 ALTSDTGKYTCVATNPAGE 3327



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 3469 WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 3526

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 3527 PHINGSEEH 3535



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 3523 VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 3580

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 3581 GEVLRISTAQVEDTGRYTCLASSPAGD 3607



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 3767

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 4197 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254

Query: 1134 TV 1135
            TV
Sbjct: 4255 TV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 4268 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 4321

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G     G
Sbjct: 4322 DSGTYVCTAENSVGFVKAIG 4341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 4451 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 4506

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 4507 FECVARNLMG 4516



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  KI W  N+  +    RY+ T D +   L I +   +D+GIY C A+NS G+   + +
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 2863 LR 2864
            LR
Sbjct: 696  LR 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 994  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 1106

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 1107 PPPIITWAK 1115



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 265  PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP I     P    +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 1509

Query: 323  LRVRNTQKSDSGHYTLLAENPNG 345
            L ++N +++D G Y     N  G
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 7/149 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            SH   I+   G +I  EC V+    PT  + W  +  PL      +   D  ++ L + +
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKN 2352

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
             +  D+G Y C A N  G       L      +I  + + P+    +  VE+   +   +
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE---NISVVEKNSVSLTCE 2409

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEG 2926
                 +P   + K  W + ++   +++ G
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSG 2438



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   + W+ +G P++     +     G   L IL A  ++ G Y C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2067 VKV 2069
            VKV
Sbjct: 2661 VKV 2663



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 3124

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 3242 QVPPSVAGAEI 3252



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 3439 SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 3494

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 3535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 4100 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSS 4157

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 4158 STSTKLTVHVPPR--IRSTEGH 4177



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 4194 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 4251

Query: 997  ANLTI 1001
             +LT+
Sbjct: 4252 VSLTV 4256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 6/142 (4%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
            Q  + +    L I++    DEG Y+C+A +SAG         V++P     +P      +
Sbjct: 474  QYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVP-----NN 528

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V  G+ A     I S +   + W R    +    +   I    N  L + +    D G
Sbjct: 529  VTVTPGERAVLTCLIISAVDYNLTWQRNDRDV-RLAEPARIRTLANLSLELKSVKFNDAG 587

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C  ++  G    S  L V+
Sbjct: 588  EYHCMVSSEGGSSAASVFLTVQ 609



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK ++ W  N + I  S+R     D     L +K   P+D+G Y C A N  G    +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 1798 STL-FVQSKASLQLESQHESALQKIQQLE 1825
            STL ++++   + ++S+   AL  I  +E
Sbjct: 694  STLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 775  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449

Query: 1003 TKKDII 1008
                II
Sbjct: 1450 VPPTII 1455



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 3833 ITQIKSHTVE----ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            IT   SH  E      + +  EC V+    P   + W ++G  L        + D G + 
Sbjct: 2292 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI- 2347

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGM 3937
            L +  ++  D+G Y+C AVN  G    K  +S    P II  ++ P  +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2396



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            P   + WF +G  L      R     G   L IL   E+N+G Y CVATN+ G
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            DV    P+   C       PT+   W+ +G P  +  +V  L   G   L I      DA
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDA 2843

Query: 3766 GEYTCRATNKWG 3777
            G YTC A N+ G
Sbjct: 2844 GRYTCVAVNEAG 2855



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL TL D+ +
Sbjct: 3334 L------NVYVTPTI-RGNKDEAEKLMTLVDTSI 3360



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 3581

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 3685

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 3686 -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3744

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 3745 TWRKDGAVLAGNHARYSILENGFLHI---QSAH 3774



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L IA V+  D+G YT +A N AG +  S  +TV 
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAI 4187



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP + Q P N  +  G  A     +       +TW +N + +  +    I T  N  +L 
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLE 577

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
           +++ + +D+G Y  +  +  G    S +L V+ P +  V  +   +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSF 623



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 790  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 847  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 897  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 951

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 952  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 1236

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQE 1260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFET-RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            VY PP     L +    +    H  T   +  G+P+  + WLK+G  ++A+         
Sbjct: 1635 VYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR--IEA 1692

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
            G   L+++S    D G+Y C A S  G  E K  + V     IE
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 1736



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 2039 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDID 2097

Query: 860  IRV 862
            +RV
Sbjct: 2098 LRV 2100



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 2099 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 2156

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              + ++     +QD+G YTC A +  G  E
Sbjct: 2157 SVLKIE--DAQVQDTGRYTCEATNVAGKTE 2184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R+  NI  VE  +V L C     G     + WF +G P+   +  R         L L+ 
Sbjct: 2391 RSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQ 2446

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
               ED+G YTC   N  GE      L V+    ++ E+
Sbjct: 2447 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN 2484



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W+KDG P++ S+ +  I + G + L +M    EDAG YT    N  GE
Sbjct: 2414 PLPSITWFKDGWPVSLSNSV-RILSGGRM-LRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P+  + WYKDG+P+ +   +    N G+ +L I   +  D G YT  A N  GE
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGE 2753



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG P+ +S ++      G   L I    V DAG YTC A N  G+ +   ++ ++
Sbjct: 2811 WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+ N++EG     EC    +  P +T  W+ NG+ I          D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPVIT--WYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2177 EDSGTYMCKATNKLG 2191
             D+G Y+C+A N  G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 3147 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
               L +      DSG YTC A +  G A+
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 3449 KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 3504

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3536



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 3769

Query: 325  VRNTQKSDSGHYTLLAENPNG 345
            +++   +D+G Y  +A N  G
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAG 3790



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 4106 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162

Query: 860  IRV 862
            + V
Sbjct: 4163 LTV 4165



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 4419 CVATNEAGVVERS 4431



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 4427 VVERSMSL 4434



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 4433 SLTLQSPPIITLEPVE 4448



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKI 876



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + W KD R +  S+ +T F N G + + I+S  + DAG Y C A N+ G
Sbjct: 1952 ITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +  A  +DTG YT  A
Sbjct: 2029 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVA 2085

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 3261 GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTS 4160

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 4161 TKLTVHVPPRIRSTEGHYTVNENSQAI 4187



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP--FATGSR 3743
            T  D    PP   +++ +N+ V  G      C +    D    + W  N R    A  +R
Sbjct: 512  TFFDVSEPPP--VIQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPAR 567

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            + TL +   ++L++  +   DAGEY C  +++ GS+  +  +T
Sbjct: 568  IRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 700  EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 754

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 755  GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 798



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 1236

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTV 1264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++ +LL SG    T  + G + +DI      
Sbjct: 1929 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNRLL-SGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1985 DAGIYKCVAINSAG 1998



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 1176 KPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +P      S+P    V+ GK+I LEC ++ +  PT  V W  +G  +      +   +  
Sbjct: 2289 RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGH 2346

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
             + L  IH   +DTG Y   AVN  G       + V     I+ + ++ + I  ++
Sbjct: 2347 ILQLKNIHV--SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+ E QS    C +   P P   + W+ +G+ LQ    +   +   F  L I  V    +
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPE--ITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545

Query: 1915 GEYTCKAINNLGQAVSSIRLNV 1936
            G YTC A +  G    S  LNV
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNV 2567



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P D+ +  NS     C       ++  + WF +G PL +   ++ +   G   L+I    
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPAT--ITWFKDGTPLESNRNIRILP--GGRTLQILNAQ 2637

Query: 3624 QRDAGLYTCKATNRHGE 3640
            + +AG Y+C ATN  GE
Sbjct: 2638 EDNAGRYSCVATNEAGE 2654



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 51/193 (26%), Positives = 78/193 (40%), Gaps = 41/193 (21%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            P+  + W+ +G+P  +   V+   + G   L I      D G YTC A+N          
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASN---------- 2749

Query: 3785 ITCSAKRDIVLESQLPQGMSGEKIKE----LERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            I    + D  +  Q+P   S +K+ E    L+ GR  +A  ++ I++ P           
Sbjct: 2750 IAGEDELDFDVNIQVPP--SFQKLWEIGNMLDTGRNGEA--KDVIINNP----------- 2794

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
                  +   C       P L   WY++G  L S  +   +   G V L I     ED+G
Sbjct: 2795 ------ISLYCETNAAPPPTLT--WYKDGHPLTSSDKV-LILPGGRV-LQIPRAKVEDAG 2844

Query: 3901 EYICRAVNDFGED 3913
             Y C AVN+ GED
Sbjct: 2845 RYTCVAVNEAGED 2857



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+I++   S + E    P       + W+ +G PL +  +V  +   G  +L+I      
Sbjct: 2788 DVIINNPISLYCETNAAP----PPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVE 2841

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            DAG YTC A N  GE ++   ++V
Sbjct: 2842 DAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T+  T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 3354 TLVDTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 3409

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3519

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 3520 ILKV-------LEPPHINGSEEHEEI 3538



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 4438 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4494

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 4495 YIADAQ---KEDTSEFECVARNLMGS 4517



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P+     KN   T G  V +  + T    P  ++ W  N   +   HR++ T D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG- 664

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
               L I  A  +D G Y C A+N+ G     S+++
Sbjct: 665  --TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI W  N   +    R+++TSD    TL + +   +D+GIY C A N  G    +ST
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 3001 V 3001
            +
Sbjct: 696  L 696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 756

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 757  -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 794  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 854  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICV 1339

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 1340 AVNEAGTTERKYNLKV 1355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAG 1345



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   P  + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNF---PNEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 1493

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 1471 VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 1527

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 1528 SNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915

Query: 1136 ETRSSID 1142
                S++
Sbjct: 1916 HEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G  + LE  +  +  PT  V W  +G P+ +    +   D G++ L +   +  DTG
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTG 2359

Query: 2049 TYMCKATNAVG 2059
             Y+C A N  G
Sbjct: 2360 RYVCVAVNVAG 2370



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 8/144 (5%)

Query: 3962 DDLYDVDKKQPPRFVTQIQS--QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            D  YD+    PP  +   +S    S+VE  +    C+ +  G P   + WF +G P+   
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLS 2430

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
            N    +   G   +       ED+G+Y C   N  G +     +     P IV ++ L +
Sbjct: 2431 NSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-E 2487

Query: 4080 HMKSIEKIREMEASWQVTPEQVVE 4103
             +K  EK + +  + +VT   V E
Sbjct: 2488 DVKVKEK-QSVTLTCEVTGNPVPE 2510



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + W+ +G  L+S    R     G   L IL    +++G Y+C A N  G+ 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 1929 VSSIRLNV 1936
            +    + V
Sbjct: 2656 IKHYEVKV 2663



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV 3622
            +P ++ +  N++   EC    +  +S+   W+ +G+PL +   V    + G   L+I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 3623 YQRDAGLYTCKATNRHGE 3640
               D G YTC A+N  GE
Sbjct: 2736 QISDTGRYTCVASNIAGE 2753



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDL 1509
            PK ++  +    +  EC+   +  ++L   W+K+GQP+        I   G+  L I + 
Sbjct: 2681 PKEVKIKVNNT-LTLECEAYAIPSASLS--WYKDGQPLKSDDHVN-IAANGHT-LQIKEA 2735

Query: 1510 IAEDSGIYTCRAVNLVGTDEV 1530
               D+G YTC A N+ G DE+
Sbjct: 2736 QISDTGRYTCVASNIAGEDEL 2756



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/120 (30%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            EDS +Y  R  V   +  A    + L     +   +SA  EC     P P  R  W  +G
Sbjct: 2856 EDSLQYDVRVLVPPIIKGAN---SDLPEEVTVLVNKSALIECLSSGSPAP--RNSWQKDG 2910

Query: 1885 K-VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            + +L+  H    SN      L IL     D G Y C A N  G A     LNV    S+I
Sbjct: 2911 QPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2967



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 2986 CEVSGFPPPDL--SWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 3041

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 3042 GESKKKFSLTVYVPPS-IKDHDSES 3065



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 8/151 (5%)

Query: 2194 VNTCTLKVAGHRNI-ILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV---TELR 2249
            +NT TL V G R + I+  +  +G E       Q   ++ +       PP      +E  
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESL 3066

Query: 2250 GTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
               +V EG +   EC+   V  P   I +Y NG+ +  +    I  D G + L I+    
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
             D G+Y  +AIN  G       + V    SI
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 3447 VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 3502

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 3503 KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 3674

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 3675 RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 3722



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 3979

Query: 724  AVLHV 728
              LHV
Sbjct: 3980 VTLHV 3984



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 14/133 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 4217 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 4268

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 4269 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 4322

Query: 3219 SGEYVCRAYNKYG 3231
            SG YVC A N  G
Sbjct: 4323 SGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W +N + +    R+R T D    TL I +    DAG+Y C A N AG
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V    PV  +C+    G+P   I W+ + R   +GS   T  + G I +DI+     
Sbjct: 1929 NETVLVSNPVQLECKA--AGNPVPVITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3764 DAGEYTCRATNKWGS 3778
            DAG Y C A N  G+
Sbjct: 1985 DAGIYKCVAINSAGA 1999



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 3826 VSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNEQ--PIKLNTNTLIVP 3015

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            G  +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN+ GE+   
Sbjct: 2990 GFPPPDLSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 3108 ILADGQMLH 3116



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 2996 LSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 1003 TKKDI 1007
                I
Sbjct: 3054 VPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 724  AVLHVTPRATIERTSQHPETL 744
              L+V    TI       E L
Sbjct: 3332 FNLNVYVTPTIRGNKDEAEKL 3352



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 1791 LGE 1793
             G+
Sbjct: 3605 AGD 3607



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 3712 PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 3768

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 3769 HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 3887

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 3888 TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 3936

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 3937 LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 3985



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 3952

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 3993



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 4260 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 4312

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  +T +   ++   G      C       P +   W  N   I   HRYR T D   
Sbjct: 609  QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDMFIVGSHRYRMTSD--- 663

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
              L I     +D+G Y C A+N  G      TL+
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 1273 TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVT 1329

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 1330 PYDNGEYICVAVNEAGTTERKYNLKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 3510 MKV 3512
            +KV
Sbjct: 1353 LKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAG 1438



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 1671 SKKSI 1675
               S+
Sbjct: 1917 EPPSL 1921



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1946 GNPVPVITWYKDN-RLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L  +T +EG  I      E  G P   + W K G  +   S        G   L +    
Sbjct: 2203 LTQLTVIEGNLISL--LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE 2260

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
              D+  Y+C A +  G A+ +  L V  R TI  +  HP
Sbjct: 2261 KSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHP 2299



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG  + L  +      PNL   W K G  + T +  +     G   L I+     D+ 
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLI--WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2265

Query: 2714 IYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            +Y+C A+N+ G A    ++++  R  +     HP  +
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W+++G P+  +  +  + D G++ L +K ++  D+G Y C A+N  G     
Sbjct: 2318 GIPPPTVTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2375

Query: 1798 STLFVQSKASL 1808
              L V +  S+
Sbjct: 2376 YDLSVHAPPSI 2386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P   + W ++G P+E++  +  +   G   L +     +++G Y+C A NE GE +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 2963 PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GG 3017

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 3430

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 3431 FAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 3791



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 3744 ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3801

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 3802 VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 3852

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 3853 YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 4260 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 4312

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 945  WLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            W ++ R V  +  +RI T  N   ++L +KSV  +DAG Y C   +  G +  S  LT+ 
Sbjct: 553  WQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 1002 -VTKKDIIAESQHPGGLEKIQYLEDASRYSK 1031
               K  ++ ++Q   G  ++  +  A+ Y K
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPK 640



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    PK+ ++   G  V   C          K+ W  N   +   HR+R   D     
Sbjct: 612  PKVTVMPKN-QSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG---T 665

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L I +   +D+GIY C A N  GTD+ +  L
Sbjct: 666  LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            +T+T+   +   + +  + A    Q  + + V   P+  R   +++   G  V + C  Q
Sbjct: 1137 ITETRTSDSGMYLCVATNIAGNVTQAVK-LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G     + W   G  +        +     +++D  +  P D+G+YTC ATN  G   
Sbjct: 1196 --GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT--PSDAGIYTCVATNIAGTDE 1251

Query: 1396 TSCALRV 1402
            T   L V
Sbjct: 1252 TEITLHV 1258



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            +L C +E  G P+  + W+ +   VT  S  +T  + G + L +  AT  D G Y+ +A+
Sbjct: 1379 NLFCEVE--GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAI 1434

Query: 1256 NHLGSAHTSAIVRVIERSDIV-TDTQNEQAI 1285
            N  G++     + V+    I+ T+  NE ++
Sbjct: 1435 NIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 1465



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   + WYKD R ++ S+ +T   N G + ++I   +  DAG Y   A+N  G      
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 859  SIRVAARSTVT 869
            S++V    +++
Sbjct: 2005 SLQVHVAPSIS 2015



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ID  V + P  +   +++ +V+  Q V   C+ + +    L   W K+G P+ +      
Sbjct: 2096 IDLRVYVPPNIMGEEQNV-SVLISQAVELLCQSDAIPPPTLT--WLKDGHPL-LKKPGLS 2151

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            I +   V L I D   +D+G YTC A N+ G  E
Sbjct: 2152 ISENRSV-LKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3694 PPRFTVE-IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP    E   +++ V E   V   C V   G+P   I W  +G+P       H ++   F
Sbjct: 2477 PPHIVGENTLEDVKVKEKQSVTLTCEV--TGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2534

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I  +     G YTC A++  G
Sbjct: 2535 --LQITNVQVPHTGRYTCLASSPAG 2557



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  + E    P+  + W+K+G  L +   +    +    TL I   +  D+G YTC A+N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASN 2749

Query: 2722 LLGE 2725
            + GE
Sbjct: 2750 IAGE 2753



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 2/72 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KDG+P+        F + G + L I +  + D G Y C A N  G A   
Sbjct: 2898 GSPAPRNSWQKDGQPLLEDDH-HKFLSNGRI-LQILNTQITDIGRYVCVAENTAGSAKKY 2955

Query: 997  ANLTIVTKKDII 1008
             NL +     +I
Sbjct: 2956 FNLNVHVPPSVI 2967



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 14/146 (9%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYVALDLLSVY 1376
            N+  V    + L C +   G     + W  N +PIK  T     P        L ++   
Sbjct: 2973 NLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTNTLIVPGGR----TLQIIRAK 3026

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              D G YTC A NQ GE+    +L V       ++      L  +   E TS      + 
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTS----VSLE 3080

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHV 1462
             ES  + P  +T  K+   + E  HV
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHV 3106



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 3073 EGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 3129 VCRAINVAG 3137



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W +N K IE+S  +      G   + I+  +  D G Y C ASN+ G+
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 3318

Query: 146  CTARNQYGE 154
            C A N  GE
Sbjct: 3319 CVATNPAGE 3327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 3357 DTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 3412

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 3413 CVASNRAGVDNKHYNLQV 3430



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 3556 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613

Query: 860  IRV 862
            +RV
Sbjct: 3614 VRV 3616



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 3728 KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 3782

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  +G+ ++   R + ++      L+I  V   DAG YTC A N  G ++ S KL V
Sbjct: 4110 ITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 4364 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 4418

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 4419 CVATNEAG 4426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPP   VP  +VT   G +      I    D    + W +N + +  +     I     +
Sbjct: 519 PPPVIQVP-NNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEP-ARIRTLANL 574

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQ 739
           SL++ S+   D+GEY C   S  G +     L V   P+ T+   +Q
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 702  PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 757

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 758  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 799



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 1007 NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 1063

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 1064 VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 1118

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 1119 LISPFSPRH 1127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 1253

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQE 1277



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +E  P P   + WY +   +      +T N+     L +     ED+G Y+CKAIN  
Sbjct: 1382 CEVEGTPSPI--IMWYKDNVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIA 1437

Query: 1926 GQAVSSIRLNVQSKESII 1943
            G +     ++V    +II
Sbjct: 1438 GTSQKYFNIDVLVPPTII 1455



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1844 PRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            P  I   N P ++S    +    EC+++  P P+  + W+ +GK L  G       D G 
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRG- 1507

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L +      D G Y C   N  G+    I+L +    SI
Sbjct: 1508 QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 1548



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+     +   + G   L+I+ A   
Sbjct: 1650 NKQVVIAHSLTLECKAA--GNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEI 1705

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 1838 VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 1894

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 1895 RYTCVATNAAGE 1906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 1912

Query: 2199 LKV 2201
            L V
Sbjct: 1913 LHV 1915



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 2001 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 2057

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 2058 GLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 2109



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V   +PV LE     +  P++   W  +G PV            G + L +  A   DTG
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLT--WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTG 2079

Query: 2049 TYMCKATNAVGE 2060
             Y C A NA GE
Sbjct: 2080 RYTCVAVNAAGE 2091



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 2034 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVN 2087

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 2088 AAGEKQRDIDLRV 2100



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  + + Q+ + L+  +  +  CQ   +  P +   W  +G PLL K   +   +   +
Sbjct: 2103 PPNIMGEEQNVSVLIS-QAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENRSVL 2159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V  +D+G Y C ATN+ G  E    +     P I
Sbjct: 2160 KIEDAQV--QDTGRYTCEATNVAGKTEKNYNVNIWVPPNI 2197



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G ++ LEC +Q +   T  V W  +G P+          E     L L +++  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSD 2357

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            +G Y C A N  G       L V A   +I   + P  +  ++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P   + W ++G P+  SN +  +   G   L +     ED+G YTC   N  GE
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P ++ +  N SA  EC  +     + R  W  +G+PLL     K +++    IL+I    
Sbjct: 2879 PEEVTVLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQ 2934

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQV 3649
              D G Y C A N  G A     L V
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNV 2960



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/71 (33%), Positives = 31/71 (43%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N   IE S+ L      G   L +      DSG YTC A N  G+A   
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 1798 STLFVQSKASL 1808
              L +Q   S+
Sbjct: 3237 YFLSIQVPPSV 3247



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 4165 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 4222

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 4223 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 4426


>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-164L12 on chromosome 1. ).
          Length = 5635

 Score =  129 bits (312), Expect = 2e-28
 Identities = 107/384 (27%), Positives = 161/384 (41%), Gaps = 35/384 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  ++ A  E    G P P   W ++  P+      +    S   IL I    + D   +
Sbjct: 2884 VLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRILQILNTQITDIGRY 2941

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGT 4540
              VAEN  G+AK   NL V           VPPS     ++N+ V     + L  +V+G 
Sbjct: 2942 VCVAENTAGSAKKYFNLNVH----------VPPSVIGPKSENLTVVVNNFISLTCEVSGF 2991

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P D+ WLKN + ++ +    I+   G  TL I+ A   D G+Y C+AIN AGE++    
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V +P       P  K  ++     E L    V EG ++   C+    P P + WYK  
Sbjct: 3050 LTVYVP-------PSIKDHDS-----ESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3097

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            ++I  S + ++   AD   L I +A   D G Y C A N AGR      L V  P   + 
Sbjct: 3098 RMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155

Query: 4721 LPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                 P R+++V     P       T    PTI WL+    I  +   ++      + L 
Sbjct: 3156 -----PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVE 4803
            I  +   D+G +TC A+   G+ +
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQ 3234



 Score =  119 bits (287), Expect = 2e-25
 Identities = 103/380 (27%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 1148

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 1149 LCVATNIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 1257 HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 1305

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   D   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 1306 EL--TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               +T   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 1364 KEQVT---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKL 1418

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 1419 FRATPEDAGRYSCKAINIAG 1438



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/371 (27%), Positives = 155/371 (41%), Gaps = 39/371 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + W R +  ++ +   +I T +  S L ++ V   D+  +  +  + GG++  S  L V+
Sbjct: 551  LTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E          PP  T+  +N + T G  V +    TG     + W  N   +    R +
Sbjct: 610  E----------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYR 659

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             +  DGT  L I  A P+D+G Y C+A NSAG                DK     +   A
Sbjct: 660  -MTSDGT--LFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEA 701

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P +++    + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+
Sbjct: 702  P-KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLK 758

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I E    D GDY CVA N AGR T    L V  P      PA     D+ +  G      
Sbjct: 759  IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLP 813

Query: 4742 TQITSKIKPTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              +    +PTI+W R +   I   P     I +     L I N +  D GT+ C A    
Sbjct: 814  CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 4800 GQVETSAKLVV 4810
            G++++   + V
Sbjct: 874  GKIQSETTVTV 884



 Score =  115 bits (276), Expect = 5e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 4237

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 4238 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 4287

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 4288 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 4344 YVKEP-------PVFKG-DYPSNWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 4388

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 4389 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 4441

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 4442 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 4497

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 4498 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score =  113 bits (271), Expect = 2e-23
 Identities = 103/405 (25%), Positives = 158/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 1227

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 1282

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + EDGT  L+I    P D+G+Y CVA+
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAV 1341

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDK---------------EQVTNVSVLLNQLTNLFCEVEG 1386

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 1387 TPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P      ++ V   +    + Q+     P I W ++G  L    P
Sbjct: 1445 NIDVLVPPTIIGTNFP-----NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 1500 NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  110 bits (264), Expect = 1e-22
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI-VPGGRTLQI 3022

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N+ G +K   +L V           VPPS     + +   VNV
Sbjct: 3023 IR-AKVSDGGEYTCIAINQAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 3071

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 3129

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 3174

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 3235 KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  109 bits (261), Expect = 3e-22
 Identities = 100/368 (27%), Positives = 151/368 (41%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 3271 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 3330

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         TL   ++N+        + + TGT P  + WLKNG  
Sbjct: 3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI--------ECRATGTPPPQINWLKNGLP 3382

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 3383 LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 3438

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 3439 ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 3486

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 3487 HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 3541

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 3542 VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 3598

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 3599 CLASSPAG 3606



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 3054 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI--LAD 3111

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 3112 GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 3161

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 3267

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 3268 CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L  +V         + + T    P I WL+ G  +P
Sbjct: 3328 EDRIFNLNVYVTPTIRGNKDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLP 3384

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 3385 LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 3420



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/407 (25%), Positives = 164/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 4043

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 4093

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMA 4150

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 4151 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 4194

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 4195 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 4250 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 4301

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+    + VK
Sbjct: 4302 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346



 Score =  106 bits (255), Expect = 2e-21
 Identities = 91/382 (23%), Positives = 165/382 (43%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P++ W ++  P+K + + +I     K  ++  Q    D   +  VA +  G
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAG 1719

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWL 4548
              +    + V          +VPP+     +     V    L+ LD  VTG+ P  + WL
Sbjct: 1720 EKEIKYEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWL 1769

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P  
Sbjct: 1770 KDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP-- 1825

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  K++         L +++V + + +   C   G P P++ W K D+ +  ++ 
Sbjct: 1826 -----PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ- 1871

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              +   +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L 
Sbjct: 1872 GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LN 1929

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            + V+    P Q + +      P I W ++  L+  +     ++ G   ++ I +    D 
Sbjct: 1930 ETVLV-SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDA 1986

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A  +AG  E    L V
Sbjct: 1987 GIYKCVAINSAGATELFYSLQV 2008



 Score =  105 bits (253), Expect = 3e-21
 Identities = 122/485 (25%), Positives = 195/485 (40%), Gaps = 59/485 (12%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            ++ G P P +SW + + P+    K +       G  +L I +    D GEYTC A NQ G
Sbjct: 2987 EVSGFPPPDLSWLKNEQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 154  EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
            E+      +VY+ P                   S ++E ++                  Y
Sbjct: 3043 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITW--------Y 3094

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
             NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 3095 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 3152

Query: 268  IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
            I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 3153 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIA 3212

Query: 327  NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 3213 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 3253

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                         D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 3254 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREG 505
            +  L I     SD+G  TCVA N +GE      LNV     +   K   E+  TL     
Sbjct: 3302 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTL---VD 3357

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              + +  RA GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A
Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVA 3415

Query: 566  QNVAG 570
             N AG
Sbjct: 3416 SNRAG 3420



 Score =  105 bits (252), Expect = 4e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 3420

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 3421 VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 3471 RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 3526

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 3527 -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 3573

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 3574 -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 3629

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 3687

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 3688 ANYTCVASNIAGKTTREFILTV 3709



 Score =  105 bits (251), Expect = 5e-21
 Identities = 101/395 (25%), Positives = 161/395 (40%), Gaps = 35/395 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP    + Q   V   +      + D  P P + W ++  P+   P   I     +S+L 
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTS 4527
            I    V+D+  +   A N  G  + + N+ +           VPP+   + +   + V  
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW----------VPPNIGGSDELTQLTVIE 2210

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G L+ L  + +G  P ++ W K G  V  D   ++    G   L I  A   D+  Y CV
Sbjct: 2211 GNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCV 2270

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG A+ +    V +  T       T + + P EI       IV  G++I   C++ 
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPT------ITNSGSHPTEI-------IVTRGKSISLECEVQ 2317

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PTV W K G  LIK +K  ++    + + L++      D G Y CVA N AG    
Sbjct: 2318 GIPPPTVTWMKDGHPLIK-AKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2374

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V  P     +       +I V E        + +    P+I W ++G  +  +  
Sbjct: 2375 KYDLSVHAPPSI--IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNS 2432

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +++  G   +L +  T  ED G +TC    AAG+
Sbjct: 2433 VRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score =  104 bits (250), Expect = 7e-21
 Identities = 109/409 (26%), Positives = 167/409 (40%), Gaps = 41/409 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 850

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 851  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 902

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 903  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 959

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 960  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 1003

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSS-AKFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYAK 1061

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +   L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V
Sbjct: 1122 PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score =  104 bits (250), Expect = 7e-21
 Identities = 96/377 (25%), Positives = 155/377 (41%), Gaps = 34/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P  +W + +  +  +P   + +  +   L I +V ++D   +  VA N  GT   +
Sbjct: 916  GNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT 972

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             ++VV           V P+     Q ++   G  V L  K +G     V W K G+ + 
Sbjct: 973  TSVVVH----------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                      DG+  L ++    ++SG+Y C A N+AG A+   +  V +       +P+
Sbjct: 1023 TSSAKFSAGADGS--LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYV-------RPR 1073

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT- 4674
                       +P++  ++A G+ +   C++   P P + W K  +LI P   F    T 
Sbjct: 1074 VFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITWAKETQLISP---FSPRHTF 1129

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +++I+E    D G Y CVA N AG VT A KL V  P +    P     + + V  
Sbjct: 1130 LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQV 1184

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            GQ             P I W + G+ +    D +      +  L I      D G +TC 
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCV 1242

Query: 4795 ATTAAGQVETSAKLVVK 4811
            AT  AG  ET   L V+
Sbjct: 1243 ATNIAGTDETEITLHVQ 1259



 Score =  104 bits (250), Expect = 7e-21
 Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKE 1817

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 1818 FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 1868 NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 1919

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK ++L+  S    M+  
Sbjct: 1920 SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFL 1970

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1971 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 2025

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +    DTG +TC 
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSAQISDTGRYTCV 2084

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 2085 AVNAAGEKQRDIDLRV 2100



 Score =  104 bits (250), Expect = 7e-21
 Identities = 102/369 (27%), Positives = 147/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W + +  I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 3237 YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 3286

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 3287 IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 3339

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +  L D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 3340 PTIRGNKDEAEKLMTLVDT------SINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 3391

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 3392 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 3448

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3506

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 3507 IASNEAGEV 3515



 Score =  104 bits (249), Expect = 9e-21
 Identities = 101/398 (25%), Positives = 164/398 (41%), Gaps = 40/398 (10%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVF 4474
            KM    V      + E +  G P+P+I WY++N  +  S      TF  +  +I I    
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSM---TFLNRGQIIDIESAQ 1982

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + D+ ++  VA N  G  +   +L V           V PS + +   V V     VRL+
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH----------VAPSISGSNNMVAVVVNNPVRLE 2032

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +  G     + WLK+G  V     N +    G   L +  A   D+G+Y CVA+N+AGE
Sbjct: 2033 CEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             + D +  V +                PP I+   ++  V   QA+E  C+    P PT+
Sbjct: 2092 KQRDIDLRVYV----------------PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135

Query: 4655 QWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             W K G  L+K      +S + +   L+I +A  +D G Y C A N AG+      + + 
Sbjct: 2136 TWLKDGHPLLKKP---GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHE 4772
             P    N+     L  + V EG       + +    P + W ++G+ ++ ++     I  
Sbjct: 2193 VP---PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS 2249

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G    L I    + D   ++C A+  AG  +    L V
Sbjct: 2250 GGRQ-LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286



 Score =  102 bits (245), Expect = 3e-20
 Identities = 96/389 (24%), Positives = 155/389 (39%), Gaps = 31/389 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  +   R E E  G P P + W ++  P+ +  +  +   S   IL +    + D+  +
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRY 2081

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G  +   +L V           VPP+     QNV+V   Q V L  +     
Sbjct: 2082 TCVAVNAAGEKQRDIDLRV----------YVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  + WLK+G  +       I E      L I +A  QD+G+Y C A N AG+   +   
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNVAGKTEKNYNV 2189

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             + +P       P    +       + L    V EG  I   C+  G P P + W K   
Sbjct: 2190 NIWVP-------PNIGGS-------DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +      ++   +    L+IS A   D   Y CVA N AG       L+V       N 
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
             +     +I+V  G+    + ++     PT+ W+++G  + +    +++ EG+  +L + 
Sbjct: 2296 GSHPT--EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQLK 2351

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            N +  DTG + C A   AG  +    L V
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380



 Score =  101 bits (243), Expect = 5e-20
 Identities = 101/380 (26%), Positives = 148/380 (38%), Gaps = 35/380 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 1006 GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPGG-EESGEYVCTATNTAGYAKRK 1063

Query: 4496 ANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V  + R    + G+           ++V +G+ V L  +V    P  + W K  + 
Sbjct: 1064 VQLTVYVRPRVFGDQRGLSQDK----PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 1119

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P          G+  + I E    DSG Y CVA N AG      +  V          
Sbjct: 1120 ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV---------- 1167

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S 
Sbjct: 1168 ------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIV 4731
               + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V
Sbjct: 1222 P--DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 1279

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                Q  +F        KPTI+WL  G  L    P   ++ +G   +L+I +    D G 
Sbjct: 1280 A--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGE 1335

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A   AG  E    L V
Sbjct: 1336 YICVAVNEAGTTERKYNLKV 1355



 Score =  101 bits (241), Expect = 8e-20
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 3912

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 3970

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 3971 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 4013

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 4014 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 4071

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 4072 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 4126 RVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 1242 VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 1293

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 1294 PKPTIKWLHNGRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 1353 LKVH----------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 1400

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 1453

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 1506

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 1507 GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 1561

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 1562 NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 1619

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 1620 VANVAGTAEKS 1630



 Score =  100 bits (239), Expect = 1e-19
 Identities = 106/423 (25%), Positives = 169/423 (39%), Gaps = 31/423 (7%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKK-MQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T +   A  +ER + G      P I  +  ++  +V E +      E  G P+P I W++
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK 2515

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRR 4505
            +  P++   D   H  S    L I  V V  +  +  +A +  G    S +L V      
Sbjct: 2516 DGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
             G G    P      ++V V       L  +     P  + W K+G  ++ +   +IL  
Sbjct: 2574 AGVGSDGNP------EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL-- 2625

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             G  TL IL A   ++G+Y CVA N AGE     E  V +P   +K         +P E+
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL-SPKEV 2684

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
                K K+      +   C+    P  ++ WYK  + +K   +  ++  A+ +TL+I EA
Sbjct: 2685 ----KIKV---NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA--ANGHTLQIKEA 2735

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-------VVYEGQPA 4738
               D G Y CVA N AG   +   + +  P     L  +  + D         V    P 
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +  +   PT+ W ++G   P T   +++      VL I     ED G +TC A   
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNE 2853

Query: 4799 AGQ 4801
            AG+
Sbjct: 2854 AGE 2856



 Score =   99 bits (238), Expect = 2e-19
 Identities = 82/299 (27%), Positives = 123/299 (41%), Gaps = 40/299 (13%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P    +  G     + ++ G P P VTW K+G  LI +   EI+    H  L+++N   S
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGH-ILQLKNIHVS 2356

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            D+G Y  +A N  G       L+V +P  S + + RS                       
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHRS----------------------- 2392

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ + V +   V+        C  +G P P +TWF +   +    + +IL   SG   L 
Sbjct: 2393 PENISVVEKNSVS------LTCEASGIPLPSITWFKDGWPVSLSNSVRIL---SGGRMLR 2443

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +   T+ D+G  TCV RN +GE      L+V+    +V    +E    + V+E + V L 
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE---DVKVKEKQSVTLT 2500

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG P+    +   H   G   L I   +      Y C A + AG
Sbjct: 2501 CEVTGNPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 35/375 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E E  G P P + W ++  P+  +   +I       IL ++ + V D+  +  VA N  G
Sbjct: 2313 ECEVQGIPPPTVTWMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT---LTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
                  +L V            PPS      + +N++V     V L  + +G     + W
Sbjct: 2371 MTDKKYDLSVH----------APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITW 2420

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G  V   + N +    G   L +++   +D+G+Y CV  N+AGE R      V +P 
Sbjct: 2421 FKDGWPVS--LSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP- 2477

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                  P     N        L+D  V E Q++  +C++ G P+P + W+K  + ++  +
Sbjct: 2478 ------PHIVGENT-------LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               +   +    L+I+       G Y C+A + AG  + +  L V        + +    
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
             D+ V    P     +  S    TI W ++G  +    + +++  G    +L  N  E++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL--NAQEDN 2640

Query: 4788 TGTFTCRATTAAGQV 4802
             G ++C AT  AG++
Sbjct: 2641 AGRYSCVATNEAGEM 2655



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 95/380 (25%), Positives = 157/380 (41%), Gaps = 34/380 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E +  P P + WY++  P+ +S    I       +L I +  VED+  +  VA N  G  
Sbjct: 2800 ETNAAPPPTLTWYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857

Query: 4493 KCSANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                ++ V+     +G    +P       + V V   +   ++   +G+      W K+G
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLP-------EEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2910

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            + +  D  +K L       L IL     D G+Y CVA N+AG A+               
Sbjct: 2911 QPLLEDDHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAK--------------- 2953

Query: 4612 PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             K      + PP +I P  + + V     I  +C++ G P P + W K ++ IK +    
Sbjct: 2954 -KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +       TL+I  A   D G+Y C+A N AG       L V  P    +  + + L  +
Sbjct: 3013 I--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-LSVV 3069

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG     + +  +   P I W + G +I E+   +++ +G   +L I      DTG 
Sbjct: 3070 NVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQ 3127

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + CRA   AG+ + +  L V
Sbjct: 3128 YVCRAINVAGRDDKNFHLNV 3147



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 88/301 (29%), Positives = 127/301 (42%), Gaps = 37/301 (12%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 1051

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 1052 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 1090

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 1091 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 1143

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 579  Y 579
            +
Sbjct: 1257 H 1257



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF 4137

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 4138 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 4184

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 4185 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 4241

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 4242 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 4286 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKAIG 4341

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 4394

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 4395 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 88/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 1227

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 1268

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 1269 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 1318

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
             G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ + ++V  
Sbjct: 1319 DGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVTNVSVLL 1374

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 1375 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCK 1432

Query: 565  AQNVAGST 572
            A N+AG++
Sbjct: 1433 AINIAGTS 1440



 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 96/388 (24%), Positives = 160/388 (41%), Gaps = 36/388 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E        E  G PLP I W+++ +P+  S   +I   S   +L + Q  +ED+  +
Sbjct: 2398 VVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRMLRLMQTTMEDAGQY 2455

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTG 4539
              V  N  G          EE++  G   +VPP      T ++V V   Q V L  +VTG
Sbjct: 2456 TCVVRNAAG----------EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                ++ W K+G+ +Q D  + I+   G   L I       +G+Y C+A + AG      
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
               V +      P      ++  PE      D  V         C+    P  T+ W+K 
Sbjct: 2564 SLNVFV-----SPTIAGVGSDGNPE------DVTVILNSPTSLVCEAYSYPPATITWFKD 2612

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP---D 4716
               ++ ++  ++       TL+I  A  ++ G Y CVA N AG +    ++KV  P   +
Sbjct: 2613 GTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2670

Query: 4717 QADNL-PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
            + D   P L+P +++ +        + +  +    ++ W ++G   P   D  +    N 
Sbjct: 2671 KGDLWGPGLSP-KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ--PLKSDDHVNIAANG 2727

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              L I      DTG +TC A+  AG+ E
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDE 2755



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 64/209 (30%), Positives = 88/209 (42%), Gaps = 8/209 (3%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYP 421
            +   QY    +    EER       L P  +      +D  V E +     C VTG P P
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            E+TW  + + +++D  H I+   SG   L ITNV +  +G  TC+A + +G  +    LN
Sbjct: 2510 EITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V     +           + V    P  L   A   P   ITW KDG P+  N  +RI  
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2626

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G  TL I  A+  +A  Y C A N AG
Sbjct: 2627 --GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 3896

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 3951

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 4006

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 4007 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 4065 GTALGKIKL 4073



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 99/397 (24%), Positives = 159/397 (40%), Gaps = 41/397 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N  V  
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1934

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+ + +        L       + I  A   D+G Y+CV
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1992

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1993 AINSAGA----TELFYSL------------QVHVAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++ A   D G Y CVA N+AG    
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 2095 DIDLRVYVPPN-----IMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              +    N +VL I +   +DTG +TC AT  AG+ E
Sbjct: 2150 LSI--SENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 96/379 (25%), Positives = 156/379 (41%), Gaps = 42/379 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W   +  I  S  +++ +  T   L I+    +D+ ++  +A N  GT K +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            + L   E           P   +    + V  G +  ++ K +G  P  V W K   +++
Sbjct: 694  STLRYIEA----------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P   +  L  D    LL I E    D+G Y CVAIN AG A                   
Sbjct: 744  P---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI--------------- 785

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             T    +PP  I+   D  +  G  +   C + G P PT++W + D +   S+ F +S  
Sbjct: 786  -TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 4675 ADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +   T  L I   +  D+G Y C A N  G+  + ++  VT       L  ++P    V+
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK--IQSETTVTVTGLVAPLIGISPSVANVI 902

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQ      T +     P  +W++  A++ + P   +  +G+   L I     +D G +
Sbjct: 903  -EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEY 958

Query: 4792 TCRATTAAGQVETSAKLVV 4810
            TC A+  AG    +  +VV
Sbjct: 959  TCVASNVAGTNNKTTSVVV 977



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 86/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ +  G     + W 
Sbjct: 1533 KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY 1582

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 1583 KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 1638

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   CK  G P P + W K    +K +  
Sbjct: 1639 -----PMIEG-----NLATPLNKQVVI-AHSLTLECKAAGNPSPILTWLKDGVPVKANDN 1687

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             ++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 1688 IRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 1742

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G LI E   F+++  G    L+I      +T
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNT 1800

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTV 1822



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V+G P P+++W  N++ I+ + N  I+    G   L I    +SD G  TC+A N++G
Sbjct: 2986 CEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 3043 ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3101

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 3102 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 3137



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 87/367 (23%), Positives = 146/367 (39%), Gaps = 17/367 (4%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W+++  P++++ + +I        L I     +++  ++ VA N  G       
Sbjct: 2603 PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V       +G +  P   L+ + V +     + L+ +        + W K+G+ ++ D
Sbjct: 2661 VKVYIPPIINKGDLWGPG--LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2718

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                I      +TL I EA   D+G+Y CVA N AGE   D +  + +P +  K      
Sbjct: 2719 DHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
              +         KD I+     I   C+    P PT+ WYK G  L    K   +     
Sbjct: 2777 MLDTGRN--GEAKDVII--NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PG 2829

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L+I  A  ED G Y CVA N AG  ++   ++V  P       +  P  ++ V   +
Sbjct: 2830 GRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP-EEVTVLVNK 2888

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  +   +    P   W ++G  + E    + +   N  +L I NT   D G + C A 
Sbjct: 2889 SALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRILQILNTQITDIGRYVCVAE 2946

Query: 4797 TAAGQVE 4803
              AG  +
Sbjct: 2947 NTAGSAK 2953



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 3607

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 3608 -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 3661

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 3662 LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 3712

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 3713 PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 3762

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 3763 LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 3815

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 3816 IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 3875

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 3876 CTVTNGAGDDKRTVDLTVQ 3894



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 3553 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 3602

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 3603 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 3640

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
              +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 3641 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 3696

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 3697 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 3752 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 4064

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 4065 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 4119

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 4120 VESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 1835 ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 1892

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 1893 AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1947

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1948 PVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 2000



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 13/217 (5%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
            R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  + + I +    KIL+N      L+I    +S++G+  C+A N +G+   +  + V 
Sbjct: 1767 MWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTD 542
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I + 
Sbjct: 1824 VPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSS 1879

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 1880 G--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 49/290 (16%)

Query: 293  PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGY 352
            P   +TWFK+G  L ++    I+      TL++ N Q+ ++G Y+ +A N  G ++    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            + V  P                       + ++    L+P+ VK+  +  +T       +
Sbjct: 2661 VKVYIPP-------------------IINKGDLWGPGLSPKEVKIKVNNTLT------LE 2695

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C     P   ++W+ + + ++ D +  I  N    H L I    +SD+G  TCVA N +G
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAG 2752

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNV----REGE--------PVVLNARAVGTPTP 520
            E      +N+      V P F + +   N+    R GE        P+ L       P P
Sbjct: 2753 EDELDFDVNI-----QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2807

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +TW KDG P+  + ++ I    G   L IPRAK  DA  Y C A N AG
Sbjct: 2808 TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAG 2855



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 52/350 (14%)

Query: 229 RLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGAD 282
           R L  +S   +S+     GE    +S+E   S   V      PPK+   P+N     G++
Sbjct: 569 RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSE 628

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
                  +G P+P++ W  N   ++ S+++ + +     TL ++N    D+G Y      
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY------ 679

Query: 343 PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
             GC+ ++      + T+              +Q  T   IE      AP+ + V  +  
Sbjct: 680 --GCLASNS-----AGTD--------------KQNSTLRYIE------APKLMVVQSELL 712

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L I      D+G 
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGD 769

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TCVA N++G    +  L+V        P F++  + +++  G  V L     G P P I
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI 824

Query: 523 TWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            W++ D +PI   P  +   +      L I    ASD   Y C A+N  G
Sbjct: 825 KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFG 874



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/302 (24%), Positives = 132/302 (43%), Gaps = 33/302 (10%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P+  K++       + +    P   ++W+K+GQ L  S+ H  I  + HT L+++  Q S
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANGHT-LQIKEAQIS 2738

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR--ETEERIEISEKA 389
            D+G YT        C+ ++  +A E   +  V  Q    +  + Q+  E    ++     
Sbjct: 2739 DTGRYT--------CVASN--IAGEDELDFDVNIQ----VPPSFQKLWEIGNMLDTGRNG 2784

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
             A         +DV         C     P P +TW+ +   +    + K+L+   G   
Sbjct: 2785 EA---------KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS--SDKVLILPGGR-V 2832

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I    + D+G  TCVA N++GE + Q  + V+    ++     +    + V   +  +
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSAL 2891

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +   + G+P PR +WQKDG P++ +   +  ++G    L I   + +D   Y C A+N A
Sbjct: 2892 IECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNG--RILQILNTQITDIGRYVCVAENTA 2949

Query: 570  GS 571
            GS
Sbjct: 2950 GS 2951



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/311 (23%), Positives = 128/311 (41%), Gaps = 40/311 (12%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 3304 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 3348

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               +EK +         D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 3349 ---AEKLMT------LVDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLL- 3392

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 3393 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 3448

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 3449 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 3505

Query: 563  CTAQNVAGSTA 573
            C A N AG  +
Sbjct: 3506 CIASNEAGEVS 3516



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 3625 TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 3682

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 3683 DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 3732

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 3790

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 3791 TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 3895 VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 3950 GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 3984



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 3769

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 3819

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 3880 NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 3923

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 3980

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 3981 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4035

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 4036 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 9/163 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 2030 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSAQISDTGRYTCVAVN 2087

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 2088 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 2142

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P++  P L I  +   S L I  A+  D   Y C A NVAG T
Sbjct: 2143 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKT 2183



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 722  ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 779

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 780  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 829

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 830  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 885

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 886  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 936  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 986

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 987  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPGGE 1044

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 60/204 (29%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 380  EERIEISEKALAPQFVK-----VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            E+ ++   + L P  +K     + ++  V   K    +C  +G P P  +W  + + + +
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
            D +HK L N      L I N  ++D G   CVA N +G       LNV     V+ PK  
Sbjct: 2916 DDHHKFLSN---GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-- 2970

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
                 L V     + L     G P P ++W K+  PI  N    I    G  TL I RAK
Sbjct: 2971 --SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAK 3026

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD   Y C A N AG +  +  L
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSL 3050



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 101/475 (21%), Positives = 177/475 (37%), Gaps = 49/475 (10%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W +   P V   + +++  + +G V  + K +   D G YTC A N  GE  
Sbjct: 1852 GIPNPSITWLKDDQP-VNTAQGNLKI-QSSGRVLQIAKTLLE-DAGRYTCVATNAAGETQ 1908

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              + +                    VS  V+ +           +        +  T  +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
              +  ++   E   + +    + +     G      +TE+  SL     P I+       
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAG------ATELFYSLQVHVAPSISGSNNMVA 2022

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +      + + +  G P P +TW K+G   ++S  + +        L + + Q SD+G Y
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSP-VSSFSNGLQVLSGGRILALTSAQISDTGRY 2081

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T        C+      AV +  E              +QR+ + R+ +    +  +   
Sbjct: 2082 T--------CV------AVNAAGE--------------KQRDIDLRVYVPPNIMGEE--- 2110

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              Q+  V   +     C+    P P +TW  +   +       I  N S    L I +  
Sbjct: 2111 --QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---VLKIEDAQ 2165

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            + D+G  TC A N +G+T     +N+     +      +  + L V EG  + L   + G
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGS---DELTQLTVIEGNLISLLCESSG 2222

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             P P + W+K G P++ +   R+    G   L I  A+ SDAA Y C A NVAG+
Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 3503

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 3560

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 3561 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
            P  V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 1460 PNEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 1510

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 1567

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 1568 ECETRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 1625

Query: 571  S 571
            +
Sbjct: 1626 T 1626



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/281 (24%), Positives = 114/281 (40%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 1851 NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 1901

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 1902 NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1938

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+ ++R +    +   L   +    + I +  +SD+G+  CVA N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQIIDIESAQISDAGIYKCVAIN 1995

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1996 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +  A+ SD   Y C A N AG
Sbjct: 2051 P-VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 2090



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 13/177 (7%)

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            V  D  V    + + +C   G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 1553 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 1609

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
            +SDS   TC   N +G       ++V      V P      +T LN  V     + L  +
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECK 1664

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P+P +TW KDGVP+  N  +RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 12/168 (7%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 4236

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G
Sbjct: 4292 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 4315

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K    + V+E          PP F     +  +    G
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE----------PPVFKGDYPSNWIEPLGG 4365

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 4366 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 4421

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 4422 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 4464

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 4465 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 4520



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 52/187 (27%), Positives = 81/187 (43%), Gaps = 11/187 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+   + +++  T G      C  TG P P++ W +ND  I   + +++    + +  L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM----TSDGTLF 667

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V+ 
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVME 722

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N AG 
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGR 780

Query: 572 TATRARL 578
              +  L
Sbjct: 781 ATGKITL 787



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
            L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 1307 LTGREPGISILEDGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 1363

Query: 398  CQ---DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
             +   +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GKILKLFR 1420

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
             T  D+G  +C A N +G +     ++V+    ++   F    S +  R+   V L  + 
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD---VALECQV 1477

Query: 515  VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 1533

Query: 572  TATRARL 578
             A   +L
Sbjct: 1534 QAKDIKL 1540



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 909

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 966

Query: 570 GS 571
           G+
Sbjct: 967 GT 968



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 4426 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 4480

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 4481 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 4521



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG +    C  +G P P + W      +  D   ++ +  SG   L I+    SD+ +
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL-SGGRQLQISIAEKSDAAL 2266

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             +CVA N +G    +  L V  +  +         + + V  G+ + L     G P P +
Sbjct: 2267 YSCVASNVAGTAKKEYNLQVYIRPTIT--NSGSHPTEIIVTRGKSISLECEVQGIPPPTV 2324

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            TW KDG P+I    + I  +G    L +     SD   Y C A NVAG T
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAVNVAGMT 2372



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 4314

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G   F   +  +  ++   P F   + +  +   G   +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG---FVKAIGFVYVKE--PPVFKGDYPSNWIEPLGGNAIL 4369

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/345 (22%), Positives = 130/345 (37%), Gaps = 37/345 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I +V + D   +  +A +  GT +      V E          PP       NV VT 
Sbjct: 484  LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE----------PPPVIQVPNNVTVTP 533

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L   +      ++ W +N + V+     +I       +L +      D+G+Y C+
Sbjct: 534  GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCM 592

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              +  G +       V                  PP++    K++    G  +   C   
Sbjct: 593  VSSEGGSSAASVFLTVQ----------------EPPKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P P + W   D  I  S  ++M  T+D  TL I  A P+D G Y C+A NSAG     
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRM--TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            + L+  +  +      +    +++V  G     + + +    P ++W +    +   P  
Sbjct: 694  STLRYIEAPK-----LMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPST 746

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +I +    +L I  T + D G +TC A   AG+      L V S
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D  V     T   C     P   +TWF +   +  + N +IL    G   L I N    
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQED 2639

Query: 459  DSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            ++G  +CVA N++GE      + V     I K  +  P    +   + ++    + L   
Sbjct: 2640 NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE 2697

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   P+  ++W KDG P+  +  + I  +G   TL I  A+ SD   Y C A N+AG
Sbjct: 2698 AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAG 2752



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 3762 ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 3876

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 3877 TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 3932 KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 74/294 (25%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            +G+         G P P + W ++GQ L   + H  ++TH    L++   +  DSG YT 
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG-MVLQLLKAETEDSGKYTC 3506

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            +A N  G +     L V  P           +I  +++ E     EIS     P     C
Sbjct: 3507 IASNEAGEVSKHFILKVLEP----------PHINGSEEHE-----EISVIVNNP-LELTC 3550

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                +   KMT       GRP P+        Q++            G   L I+   + 
Sbjct: 3551 IASGIPAPKMTWMK---DGRPLPQTD------QVQ---------TLGGGEVLRISTAQVE 3592

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G  TC+A + +G+   +  + V     +         + L  R+   V L  ++   P
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ---VTLECKSDAVP 3649

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P ITW ++G  +   P +RI +  G   L I  A   D A Y C A N+AG T
Sbjct: 3650 PPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGKT 3701



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L I  V   D+G  TC+
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQIAFVQPGDAGHYTCM 4149

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 4150 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4204

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 4205 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 61/277 (22%), Positives = 112/277 (40%), Gaps = 28/277 (10%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            ++   V    P  + +++NG  +  D   + L+E  +  L I +    D G YEC+A++S
Sbjct: 448  QIPCSVDSLLPFTLSFVRNGVTLGVD---QYLKESASVNLDIAKVTLSDEGFYECIAVSS 504

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG  R      VS                 PP +I+   +  V  G+    +C I+    
Sbjct: 505  AGTGRAQTFFDVS----------------EPPPVIQVPNNVTVTPGERAVLTCLIISAVD 548

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
              + W + D+ ++ ++  ++ RT    +L +      D G+Y C+  +  G    +  L 
Sbjct: 549  YNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            V +P +   +P     ++     G         T   KP I W      I  +  ++M  
Sbjct: 608  VQEPPKVTVMP-----KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            +G    L I N   +D G + C A+ +AG  + ++ L
Sbjct: 663  DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 12/201 (5%)

Query: 402  DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
            +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 955

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 956  GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 1010

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             + W K G  +I     +  + G   +L +      ++  Y CTA N AG    + +L  
Sbjct: 1011 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068

Query: 581  XXXXXXXXXQKRLHLPRPTKV 601
                     Q+ L   +P ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEI 1089



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 12/188 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++V  +  VT G+     C +       +TW  NDR +R        +    N +L 
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVL 510
           + +V  +D+G   C+  ++ G +A    L V E  +V V PK        +   G  V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK------NQSFTGGSEVSI 631

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P+I W  + + I+ +   R+ +DG   TL I  A   DA  Y C A N AG
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688

Query: 571 STATRARL 578
           +    + L
Sbjct: 689 TDKQNSTL 696



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N+ G+++    L   
Sbjct: 2996 LSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   EC    V  P   I WY NG+ +  ST ++ 
Sbjct: 3054 VPPSIKDHDSESLSVVNV---REGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEI 3108

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 3109 LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 104/477 (21%), Positives = 174/477 (36%), Gaps = 55/477 (11%)

Query: 99   PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            P P ++W +   PL   +K  +      G   L I +    D G YTC A N+ GE    
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLIL----PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860

Query: 159  ----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                V + P                 + S  +E  + G+        +  Q +   +   
Sbjct: 2861 YDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--H 2918

Query: 215  HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
            H    + ++       + ++     + +   G +    +  +      V P  I  K  N
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-----VPPSVIGPKSEN 2973

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
              +          ++SG P P ++W KN Q  I  N + +I      TL++   + SD G
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQP-IKLNTNTLIVPGGR-TLQIIRAKVSDGG 3031

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERIEISEKALAPQ 393
             YT +A N  G       L V  P    ++D  S+ ++    RE T   +E    A+ P 
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSLECESNAVPPP 3089

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
             +   ++     G+M      +T   + E+   + D Q+   +  K  V+++G +     
Sbjct: 3090 VITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVSDTGQYVCRAI 3133

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV               +G       LNV     +  P+      T++     PV L   
Sbjct: 3134 NV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS----NPVTLTCD 3174

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C A N+ G
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 4432 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 4482

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 4483 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 4531



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C+  G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 1718

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  I
Sbjct: 1719 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 1776 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 1812



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 1238

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
             TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 1239 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 1296

Query: 521  RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W  +G  +    P + I  DG  + L I      D   Y C A N AG+T  +  L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 14/157 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA----EISVK 3137
            I WF +G  +E++  IR +   G   L+IL  +  ++G YSC ATN+ G+     E+ V 
Sbjct: 2607 ITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVY 2664

Query: 3138 L-ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +   ++K     P  +   + ++ +K   +   EC    +  P   + WY +GQP++   
Sbjct: 2665 IPPIINKGDLWGPGLSP--KEVK-IKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDD 2719

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +   ++ G   L I   Q  D+G Y C A N  GED
Sbjct: 2720 HVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGED 2754



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 62/288 (21%), Positives = 104/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 4132

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 4133 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4192

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 4193 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 4250

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 4251 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 4303

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +   G++ V+ P
Sbjct: 4304 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 3515

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 3516 SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3569

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 3570 PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 3608



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +  S  IR + A G V+  I+  + +D   Y+C A+N+ G    
Sbjct: 3367 TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYTCVASNRAGVDNK 3424

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L+            T  I  ++    G S    C       P M   W  +GQP+  
Sbjct: 3425 HYNLQVFAPPNMDNSMGTEEITVLK----GSSTSMACITDGTPAPSM--AWLRDGQPLGL 3478

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + TVS  G +VL +   +  DSG+Y C A N+ GE
Sbjct: 3479 DAHL-TVSTHG-MVLQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 17/203 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +L+IL T+ TD G Y C A N  G A+   ++ +       G K    T + N       
Sbjct: 2927 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN------- 2979

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                  C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C
Sbjct: 2980 NFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTC 3035

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----E 3280
             A N+ GE   + ++  Y    +     +  S+  +RE  S+    +     P      +
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3095

Query: 3281 PPKFITQIQDVTKLVEGQSAHFE 3303
              + IT+   V  L +GQ  H +
Sbjct: 3096 NGRMITESTHVEILADGQMLHIK 3118



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 64/257 (24%), Positives = 98/257 (38%), Gaps = 22/257 (8%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P + W +K +P++  +   +R    +G   L I      D   Y+C A N  G A 
Sbjct: 2222 GIPPPNLIWKKKGSPVLTDSMGRVRI--LSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279

Query: 157  ----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
                  VYI+P                R  S ++E +  G    T    +    +    G
Sbjct: 2280 KEYNLQVYIRPT-ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG 2338

Query: 213  TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES-DVQISTEIDRSLGPVSPPKIA-- 269
             +            E  +L+  +   S T RYV  + +V   T+    L   +PP I   
Sbjct: 2339 VEILD---------EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389

Query: 270  -QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             + P N  + E        + SG P P +TWFK+G  +  SN   I++      LR+  T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQT 2447

Query: 329  QKSDSGHYTLLAENPNG 345
               D+G YT +  N  G
Sbjct: 2448 TMEDAGQYTCVVRNAAG 2464



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 3728 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 3784

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 3785 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 3883



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           + ES +  L I  VTLSD G   C+A + +G    Q   +V E      P  ++  + + 
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE-----PPPVIQVPNNVT 530

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V  GE  VL    +      +TWQ++   +      RI T    S L++   K +DA  Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEY 589

Query: 562 QCTAQNVAGSTA 573
            C   +  GS+A
Sbjct: 590 HCMVSSEGGSSA 601



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 260  LGPVSPPKIAQKP--RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            L  + PP I  +    + K++E        +++GNP P +TW K+GQ L     H II+ 
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS- 2530

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L++ N Q   +G YT LA +P G
Sbjct: 2531 -GGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 86/218 (39%), Gaps = 35/218 (16%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            ++ IK       E     I  ++L   W KDG+P+++   +    N G+  L IK   + 
Sbjct: 2683 EVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQIS 2738

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEV 1037
            D G YTC A N  G+     ++ I          Q P   +K+  + +     +  E + 
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI----------QVPPSFQKLWEIGNMLDTGRNGEAKD 2788

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD 1097
             I   P                S + E    P   LT    WY +G  +TS++++     
Sbjct: 2789 VIINNP---------------ISLYCETNAAPPPTLT----WYKDGHPLTSSDKVLILP- 2828

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G   L I   + ED+G YT VA N AGE  L   + V
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 74/293 (25%), Positives = 118/293 (40%), Gaps = 46/293 (15%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   + WY +G+ L+      + ++ G  TL + +    D+G YTC A N  GE      
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGEDELDFD 2759

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            V            Q P   + L +I N+ D             TGR  E     KD++ I
Sbjct: 2760 V----------NIQVPPSFQKLWEIGNMLD-------------TGRNGEA----KDVI-I 2791

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +     + E +  P       + W+ +G  + +S ++  +   G  VL+I   K  D+G 
Sbjct: 2792 NNPISLYCETNAAPPP----TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGR 2845

Query: 3121 YSCRATNKWGQ--AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            Y+C A N+ G+   +  V++      KG        +  +      +SA  EC  +    
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLV----NKSALIEC--LSSGS 2899

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P  +  W  +GQP+      K +S+    +L I  TQ  D G YVC A N  G
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAG 2950



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 66/168 (39%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 4012 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4069

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 4070 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 4121

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L IA+ Q  D+G Y C A N  G   T   +  +
Sbjct: 4122 SIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 3236 YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 3287

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 3288 ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 4431

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG P+T+S ++  I   G V L I   + EDAG YT  AVN+ GE      
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVL-ILPGGRV-LQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862

Query: 860  IRVAARSTVT-ADLGIPEQ 877
            +RV     +  A+  +PE+
Sbjct: 2863 VRVLVPPIIKGANSDLPEE 2881



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   N   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 4404

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 4405 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 1311

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 1312 PGISILEDG-TLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            ++   EC++  +  P   V W  +G PL+ K +   I D G++ +    ++  D+G Y+C
Sbjct: 2308 KSISLECEVQGIPPPT--VTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSDTGRYVC 2363

Query: 4049 RATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
             A N+ GM + K  +     P I+ + + P+++  +EK
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 4194 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 4250 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 4300

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V     I        P      P N  
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWI 4360

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 4361 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 4417

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 2104 PNIMGEEQN 2112



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 18/164 (10%)

Query: 3079 SMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            S  + W+ +G+ +++   +  + A G   L+I   + +D+G Y+C A+N  G+ E+   +
Sbjct: 2703 SASLSWYKDGQPLKSDDHVN-IAANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV--PVD-------DPDMKIEWYHNG 3189
                    QK      I N+  L  G++   +  ++  P+         P   + WY +G
Sbjct: 2761 NIQVPPSFQK---LWEIGNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG 2815

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+  S ++  +   G  VL I   +  D+G Y C A N+ GED
Sbjct: 2816 HPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 3255 DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 3312

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            D+G YTC ATN  GE      L V     +     +    EK+  L DTS
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTI---RGNKDEAEKLMTLVDTS 3359



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  +  N     GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 4402

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  N   I  SHR R   + G + ++    K  D+G Y C A+N  G  + 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQ 692

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            +  L  ++  K         +Q+   +  G     EC    +  P +K  W+     +R 
Sbjct: 693  NSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGIPPPQVK--WFKGDLELRP 744

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLE 3250
            ST +  + D    +L I  TQ+ D+G+Y C A N+ G    + T++  G   V+++
Sbjct: 745  STFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD-VGSPPVFIQ 797



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 1170 PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 1268

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 1269 ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 1308

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 1309 GREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 1368 TNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 4078 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 4131

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 15/197 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP    V  ++  ++ G+ A     +I   D ++   W  N + +  +   R +  
Sbjct: 515  DVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLT--WQRNDRDVRLAEPAR-IRT 570

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               + LE+   K  D+G Y C  +++ G +  SV L        Q+P   T +   +   
Sbjct: 571  LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV------QEPPKVTVMPKNQSFT 624

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G      C+      P  KI W  N   +  S R +  SD    + + A     D+G Y
Sbjct: 625  GGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAA---PKDAGIY 679

Query: 3223 VCRAYNKYGEDFTRATI 3239
             C A N  G D   +T+
Sbjct: 680  GCLASNSAGTDKQNSTL 696



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PP    +P   +   G      C  TG+PKP++ W +N   IV   RY++T DG
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 4489 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 4544

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 4545 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGK 875



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 756  LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 809

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 810  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 870  ENQFGKIQSETTVTVTG 886



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 789  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 849  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 1371 SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDA 1426

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST-QNEAG--LEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +   NE    L +   LE + K      + 
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 1486

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 1487 WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C        A+T    G  I+ S +++Y++      
Sbjct: 1546 PSIKGGNVTTDI-SVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 1604

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 1605 IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++ +    + G   L +      D G Y C A +  GE
Sbjct: 1664 KAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV      +L++      D+G YSC+A N  G ++  
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVN--NGKILKLFRATPEDAGRYSCKAINIAGTSQKY 1443

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +           T+  N   +   +    EC V     PD  I W+ +G+P+   
Sbjct: 1444 FNIDVL----VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLG 1497

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 1498 DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +    G  I  E  ++ +  PT  + W+K+G  +   ++   I   G+I L + ++++ D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSD 2357

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
            +G Y C AV+  G+ + K  L V    +I    + PE +  +++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 35/210 (16%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++++  N     E     +  P   + W ++G P+++ + +    + G+  L +K    
Sbjct: 2682 KEVKIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQI 2737

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G YTC A N  GE      + +Q   S Q        L +I  + D+ R    +DV 
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ-------KLWEIGNMLDTGRNGEAKDVI 2790

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +            N P  L         C     P P +   WY +G  L S  +     
Sbjct: 2791 I------------NNPISL--------YCETNAAPPPTL--TWYKDGHPLTSSDKVLILP 2828

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
              G   L I     ED+G YTC A+N  G+
Sbjct: 2829 --GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 57/266 (21%), Positives = 102/266 (38%), Gaps = 11/266 (4%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            L GNP P   W +  A L++    ++R      D SL I+++   D GEYTC A N  G 
Sbjct: 914  LAGNPIPERRWIKNSAMLLQNPYITVR-----SDGSLHIERVQLQDGGEYTCVASNVAGT 968

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               +  +                    +  T+  KA G    +   S++ + ++ ++   
Sbjct: 969  NNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF 1028

Query: 215  HSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
             +  D    V +       E     + T  Y  +  VQ++  +   +          KP 
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYA-KRKVQLTVYVRPRVFGDQRGLSQDKPV 1087

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSD 332
               +  G +     ++   P P +TW K  Q +   S +H  + + +   +++  T+ SD
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSD 1144

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESP 358
            SG Y  +A N  G +  +  L V  P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVP 1170



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 3652 VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 3710 NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 3759

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 3760 YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 3801



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 3952

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 3996



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +G  +  S+ +R +   G  +L ++ T   D+G Y+C   N  G+      L  +
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P        +E +K  +      T     +P  +I W+ +GQP++       +
Sbjct: 2476 ------VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII 2529

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S   F  L I   Q   +G Y C A +  G      ++N +
Sbjct: 2530 SGGRF--LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2568



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  EC+   V      + W+KNG+ +T       + D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHL 3145



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 3299

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+  L 
Sbjct: 3300 NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTLV 3356

Query: 1960 DDS 1962
            D S
Sbjct: 3357 DTS 3359



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 4252 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 4306

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 4307 VN--GHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     S+ +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 4400

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     ED+G YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1385 CQATNQLGEAVTSCALRVIAKKDLILE 1411
            C ATN+ G    S +L + +   + LE
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 4364 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 4419 CVATNEAGVVERSMSLTLQS 4438



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    + KN  F  G          G P P ++WT     +V  ++Y M     T D +
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM-----TSDGT 665

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L IK   P D G Y C A N  G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAG 688



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I +  G     E  ++ I   T  V W+KDG P+  +  +    + G++ L +K++ V 
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI-LQLKNIHVS 2356

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            D G Y C A N  G      +L++     II   + P  +  ++
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G  +L I  V   DAGHYTC A N  G ++TS  LT+
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 1252 TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 1305

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 1306 ELTGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPII 1392



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 3676

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++ N    D+ +YT +A N  G       L V  P
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 3712



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 4429 ERSMSLTLQSPPIITLE 4445



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 20/170 (11%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDI---------IDESVTIKPRFVTRPKSIE 1454
            AK   IL+  H   L+ I ++ DT RY    +          D SV   P  +   +S E
Sbjct: 2336 AKGVEILDEGHILQLKNI-HVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE 2394

Query: 1455 N--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            N  V+E   V   C+   +   +  + WFK+G PV++ +  R +   G   L ++    E
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPS--ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTME 2450

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            D+G YTC   N  G +     L+      IV     E  LE ++V E +S
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLVPPHIV----GENTLEDVKVKEKQS 2496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632  RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 3429 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 3485

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
              G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 3486 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 3518

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 3519 FILKVLEPPHINGSEEHE 3536



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 3605 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 3655

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 3656 LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 3700



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 3766

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 3767 F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 12/174 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C ATN  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 1188

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 1189 DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 1244

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P
Sbjct: 1245 NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKP 1296



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 1579 ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 1635

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +  I+  
Sbjct: 1636 YVPPMIEGNLATPLN--KQVVIAHSLTLECKA--AGNPSPILTWLKDGVPVKANDNIRI- 1690

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 1691 -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG PV  S+ +      G   L +   T+ DAG YTC   NA G+      L+++
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 1003 TKKDIIAES 1011
                I+ E+
Sbjct: 2476 VPPHIVGEN 2484



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 3257 SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++  L D S
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTLVDTS 3359



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 1216

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 1217 HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 1256



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T   ++ S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 1496

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 1497 GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I V  G  +  +C V+ +  PT  + W  +G P      V  L++ G I L +  I+  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GHI-LQLKNIHVSD 2357

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
             G Y C A N  G       ++  A   I+   + P+ +S
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS 2397



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 3261 GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 3319 CVATNPAG 3326



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 4131

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 4132 --SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P+ +    N     G+ V + C     G    ++ W  N   I   HR+R   +
Sbjct: 606  LTVQEPPKVTVMPKNQSFTGGSEVSIMC--SATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI-AKKDLILESQHPSGLEKIQY 1423
                 L + +  P+D+G+Y C A+N  G    +  LR I A K ++++S+    L  I  
Sbjct: 664  G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITV 720

Query: 1424 LE 1425
            +E
Sbjct: 721  ME 722



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 714 ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 769

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 770 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 826

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 881

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 938

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAG 967



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 1351 YNLKVHVPPVIKDKEQ-------VTNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 1400

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 1401 VTESSTIQTVNN--GKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+  IR + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 1725 YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLIDE 1777

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 1778 RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 1813



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEK 2092

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 2093 QRDIDLRV 2100



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 633  VYPPPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V+ PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTN--TLIVP 3015

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            G  +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   V  EC  E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 3071 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 3127 QYVCRAINVAGRD 3139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LEC    +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 4433 SLTLQS 4438



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 860  IRVAARSTVTADLGIPEQRRYI 881
            + V     +  +L  P  ++ +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVV 1654



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ + + +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 2003

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 2004 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 2053

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +   Q  D+G Y C A N  GE
Sbjct: 2054 SFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVNAAGE 2091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G+ +  EC+++ +      V W K+G P+ I  +   I D G++ L + ++   D+G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSDTG 2359

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             Y C AVN+ G  +    L+  +   I+    N    E I V+E  S
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSII---GNHRSPENISVVEKNS 2403



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G++   E ++  +  PT  V W KDG P+  +  +  I + G++ L + ++   D G Y 
Sbjct: 2307 GKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGV-EILDEGHI-LQLKNIHVSDTGRYV 2362

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
              AVN  G       + V A  ++  +   PE    +EK
Sbjct: 2363 CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   EC     P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 3073 EGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 3302 STLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)

Query: 3047 PPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP  +   K+ ++ + +      EA  +P  D    I W  +G+ I  S R R V + G 
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPD----ITWHKDGRAIVESIRQR-VLSSGS 4132

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LK 3162
              L+I   +  D+G Y+C A N  G +  S KL     +    PR    I++ EG   + 
Sbjct: 4133 --LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL-----TVHVPPR----IRSTEGHYTVN 4181

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +   A   C    +  P   I W  +   + +     T   +G ++L+    +  DSG Y
Sbjct: 4182 ENSQAILPCVADGIPTP--AINWKKDNVLLANLLGKYTAEPYGELILENVVLE--DSGFY 4237

Query: 3223 VCRAYNKYGED 3233
             C A N  GED
Sbjct: 4238 TCVANNAAGED 4248



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 788  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 900

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 901  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 956

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 957  EYTCVASNVAG 967



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 1351 YNLKVHVPP 1359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 84/375 (22%), Positives = 143/375 (38%), Gaps = 32/375 (8%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            +NI V E   V   C  E  G P   I WF +G P +  + V  L+  G   L +     
Sbjct: 2394 ENISVVEKNSVSLTC--EASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTM 2449

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+YTC   N  G       ++      IV E+ L      EK        ++  P  
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E       + + + ++H +    G RF  ++   + P      Y      P+GH+ R+  
Sbjct: 2510 EITWHKDGQPLQEDEAHHI--ISGGRF-LQITNVQVP--HTGRYTCLASSPAGHKSRSFS 2564

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVND------FGEDFTKATISCKKLPDIILQNQVPR- 3935
               FVS  I  V ++ + E +   +N           +  ATI+  K    +  N+  R 
Sbjct: 2565 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI 2624

Query: 3936 --GMKRSEALTQMEATIKKYTSEVYLTEDDL---YDVDKKQPP------RFVTQIQSQTS 3984
              G +  + L   E    +Y+        ++   Y+V    PP       +   +  +  
Sbjct: 2625 LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEV 2684

Query: 3985 LVEMETT-KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
             +++  T   EC+   +  P+  + W+ +G+PL   +    I   G+  +        D+
Sbjct: 2685 KIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVN-IAANGH-TLQIKEAQISDT 2740

Query: 4044 GEYLCRATNLYGMDE 4058
            G Y C A+N+ G DE
Sbjct: 2741 GRYTCVASNIAGEDE 2755



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 4429 ERSMSLTLQS 4438



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 87/402 (21%), Positives = 156/402 (38%), Gaps = 41/402 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 791  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 966

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 967  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 1023

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDQRGLS 1082

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 1137

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +    DSG+Y C A N+ G    + +L       I R  ++
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 1544 IPPSIKGGNVTTDI----SVLINSLIKLECETRGLPMP--AITWYKDGQPIMSSSQALYI 1597

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 1598 -DKG-QYLHIPRAQVSDSATYTCHVANVAG 1625



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 2063

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 2064 GGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V  GK+   EC+V+ +  P   + +  +G  L  A    I  D G++ L +++    D G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTG 2359

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             Y   A+N  G       ++V A  SII   + PE +  + +   +   +   IP P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 3261 GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDT--QNEQAIEQIQLLEDAA 1295
              A N  G        R+   +  VT T   N+   E++  L D +
Sbjct: 3319 CVATNPAGEED-----RIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 3359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S      G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 4399

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL+L+S   +   +   +  S        V + V + P+ +T +      + G      C
Sbjct: 575  SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMC 633

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P  ++ W  N   +   HRYR ++D     L I     +D+G Y C A N+ G
Sbjct: 634  SATGYPKP--KIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 1927 QAVSSIRLN-VQSKESIIRDSQHESALEKIQYLE 1959
                +  L  +++ + ++  S+   AL  I  +E
Sbjct: 689  TDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 897  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 952

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 953  QDGGEYTCVASNVAG 967



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 1224

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
             +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 1225 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 1907

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY + + +
Sbjct: 1908 QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNRLL 1961

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1962 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1998



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +   + +D+G Y+C A N  G+ +  + L   
Sbjct: 2043 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVY 2101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 2102 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 2152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S+    VL I   Q  D+G Y C A N  G+      +N +
Sbjct: 2153 SE-NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 54/211 (25%), Positives = 82/211 (38%), Gaps = 34/211 (16%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            S K V+IK       E     +  A+L   WY + +PLKS        N G   L I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASLS--WYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSA 1702
               D+G YTC         V S IA    +    +  Q   +  +L ++ +     R+  
Sbjct: 2736 QISDTGRYTC---------VASNIA-GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
              +VI   P+           E  AA           P   + W ++G P+ +S+++  +
Sbjct: 2786 AKDVIINNPISLY-------CETNAA-----------PPPTLTWYKDGHPLTSSDKVLIL 2827

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G   L +     ED+G YTC A+NE GE
Sbjct: 2828 P--GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633  VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 3052 VYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTH-VEI 3108

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
               G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 3109 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 3154



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 3126

Query: 842  SYTVRAVNKLG 852
             Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             NL +     I          EK+  L D S
Sbjct: 3332 FNLNVYVTPTIRGNKDE---AEKLMTLVDTS 3359



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS+ I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 4403

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 4404 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 4461

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 4462 QATGEPQPTIT 4472



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 18/270 (6%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 1102 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATNIAG 1157

Query: 154  EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
                +V +                        +   A GT       S+    +   +G 
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 1216

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
             H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 1217 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 1269

Query: 272  PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
            P N+  QE    Q   F     G P+P + W  NG+ L    +  I    + T L + + 
Sbjct: 1270 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEDGTLLVIASV 1328

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               D+G Y  +A N  G       L V  P
Sbjct: 1329 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 22/283 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 1225

Query: 131  LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
            L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 188  H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                A GT        + T K  + NG + +  +       +  LL   S        Y+
Sbjct: 1286 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337

Query: 246  GESDVQI-STEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
              +  +  +TE   +L    PP I  K +  N  +          ++ G P P + W+K+
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 1398 NVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ I+     + +     +V  I   + +++G Y C A N  G    
Sbjct: 1759 TGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKK 1816

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 1817 EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 1865

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 1866 PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 724  AVLHVTPRATIE 735
              LHV    ++E
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQIS--DTGRYTCVAVNAAGEKQR 2094

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 2095 DIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P+++I++   S   EC +  +   +  V W  +G PL+    V+ +++ G  IL++  ++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GH-ILQLKNIH 2354

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
              D G Y C A N  G       L V     II   + P +
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            +L++     +D+G Y C A N  G  +    L      S     R   +I  +E  K+  
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE--KNSV 2404

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   E + +P+      I W+ +G P+  S  ++ +S  G  +L +  T   D+G+Y C 
Sbjct: 2405 SLTCEASGIPLPS----ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCV 2458

Query: 3226 AYNKYGED 3233
              N  GE+
Sbjct: 2459 VRNAAGEE 2466



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 34/215 (15%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+    +   EC  E Y  P+  + WY +G+ L+S      + + G   L I      D+
Sbjct: 2685 KIKVNNTLTLEC--EAYAIPSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDT 2740

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G YTC A N  G+      +N+Q   S          L +I  + D  R   A       
Sbjct: 2741 GRYTCVASNIAGEDELDFDVNIQVPPSF-------QKLWEIGNMLDTGRNGEA------- 2786

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
                         +V   +P+ L         PT+   WY +G P+      K     G 
Sbjct: 2787 ------------KDVIINNPISLYCETNAAPPPTL--TWYKDGHPLTSSD--KVLILPGG 2830

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              L I  A  ED G Y C A N  GE      V+V
Sbjct: 2831 RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 3122

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 3123 SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 3170

Query: 3548 LTPEAESGNPP 3558
            LT +A +G PP
Sbjct: 3171 LTCDA-TGIPP 3180



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 785  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 843

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 844  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 1006 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 1063

Query: 724  AVL--HVTPR 731
              L  +V PR
Sbjct: 1064 VQLTVYVRPR 1073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTV-NNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 860  IRVAARSTV 868
            I V    T+
Sbjct: 1446 IDVLVPPTI 1454



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+  +   +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 1510

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1952 ITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 2010 VAPSISGSN 2018



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            +++  + V   P      + PT++  + G+S   EC ++  P P   V W  +G  L   
Sbjct: 2279 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKA 2336

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                  ++     L +  ++  D+G Y C A+N  G       L+V +  SII    H S
Sbjct: 2337 KGVEILDEGHI--LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII--GNHRS 2392

Query: 1951 ALEKIQYLEDDS 1962
              E I  +E +S
Sbjct: 2393 P-ENISVVEKNS 2403



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +C    V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 3124

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 3125 TGQYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 3126

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626  PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 3661

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 3662 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 3529 EGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS 3588
            EG  + IA     +G   T    +E   PP     P+++ ++    A   C +I   D +
Sbjct: 494  EGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550

Query: 3589 MRVEWFHNGKP--LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            +   W  N +   L   +R++T+ +     LE+  V   DAG Y C  ++  G +  S  
Sbjct: 551  LT--WQRNDRDVRLAEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVF 605

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTE 3670
            L V+    + + P+  S F  G+E
Sbjct: 606  LTVQEPPKVTVMPKNQS-FTGGSE 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PPK     K+ +      V   C       PK +I W  N   +   HRYR   D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGY--PKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              +L I     +D+G Y C A N  G D   +T+   + P +++
Sbjct: 664  -GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 916 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 972

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 973 TSVVVHVLP--TIQHGQQILSTIEGI 996



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P+++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 1446 IDVLVPPTIIG-----TNFPNEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 1496

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 1497 GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 1405 KKDLILESQ-HPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            +K +I ++Q   +GL +         +KK    + +V + P   +   S   V++ + V 
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVA 1845

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
             +C    +   N  + W K+ QPV        I   G V L I   + ED+G YTC A N
Sbjct: 1846 LQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902

Query: 1524 LVGTDEVSCRL 1534
              G  +   +L
Sbjct: 1903 AAGETQQHIQL 1913



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S P   + W+KDG P+ ++  I  +   G  +L I++ + ++AG Y+  A N+ GE I  
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658

Query: 858  ASIRV 862
              ++V
Sbjct: 2659 YEVKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+G  L +   ++     G  TL I + + D++G Y+C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2732 IKI 2734
            +K+
Sbjct: 2661 VKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +C    V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 860  IRVAARSTV 868
            + V    T+
Sbjct: 3334 LNVYVTPTI 3342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 3829 GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 3886

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 3887 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 3945

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 3946 ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 3998

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 4056

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQVP 4078



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 4126

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 4127 VLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 791  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 850  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 994  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 1003 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 1058

Query: 154  EA----ICSVYIQP 163
             A      +VY++P
Sbjct: 1059 YAKRKVQLTVYVRP 1072



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/179 (21%), Positives = 72/179 (40%), Gaps = 7/179 (3%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W   G  +      R     G   L+I   + +D+  YSC A+N  G A+    L+    
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY-- 2287

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             +       +H   I  +  G+S   EC V  +  P   + W  +G P+  +  ++ + D
Sbjct: 2288 IRPTITNSGSHPTEII-VTRGKSISLECEVQGIPPP--TVTWMKDGHPLIKAKGVE-ILD 2343

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
             G  +L +      D+G YVC A N  G    +  ++ +    +      P++++ + +
Sbjct: 2344 EGH-ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E  + P  TI WF +G  + +    R     G   L IL    +++G Y C ATN+ GE 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 2194 VNTCTLKV 2201
            +    +KV
Sbjct: 2656 IKHYEVKV 2663



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIH--FETRIE----PVGDPTMKIEWLKNGQSI 679
            P GEEDR++    ++ P       E  K+    +T I       G P  +I WLKNG  +
Sbjct: 3324 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 3383

Query: 680  EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
              SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 3384 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 3421



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 3728 KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 3784 MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 3795

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 3796 IDLQVHVPP 3804



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 4151 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 4204

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 4205 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 1253 EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 1304

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 1305 RELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 1346



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 1259 QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 1312

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 1313 GISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 1354



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 653  KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            K+  ETR    G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC 
Sbjct: 1566 KLECETR----GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCH 1619

Query: 713  AVSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
              +  G AE    + V     IE     P   Q +
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 1654



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284  QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
            + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 1623

Query: 344  NGCIVTSGYLAVESP 358
             G    S ++ V  P
Sbjct: 1624 AGTAEKSFHVDVYVP 1638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+ + +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 2003

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 2004 YSLQVHVAP 2012



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKDG P+     ++   N     L I+   V D G YTC A N  G+   + N+ I
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ WY +G+ + S + +    + G+  L I   +  D+G YT VA N AGE +L   + +
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            +   S       + L+E          +  M       ++K V +   +NP        I
Sbjct: 2763 QVPPSF------QKLWE----------IGNMLDTGRNGEAKDVII---NNP--------I 2795

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C       PT+   W+ +G  +T  S  K     G   L I  A   D G YT  AV
Sbjct: 2796 SLYCETNAAPPPTL--TWYKDGHPLT--SSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851

Query: 1256 NHLGSAHTSAIVRVI 1270
            N  G       VRV+
Sbjct: 2852 NEAGEDSLQYDVRVL 2866



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 3253 PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 3309 ALTSDTGKYTCVATNPAGE 3327



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 3469 WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 3526

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 3527 PHINGSEEH 3535



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 3523 VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 3580

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 3581 GEVLRISTAQVEDTGRYTCLASSPAGD 3607



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 3767

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 4197 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254

Query: 1134 TV 1135
            TV
Sbjct: 4255 TV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 4268 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 4321

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G     G
Sbjct: 4322 DSGTYVCTAENSVGFVKAIG 4341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 4451 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 4506

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 4507 FECVARNLMG 4516



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  KI W  N+  +    RY+ T D +   L I +   +D+GIY C A+NS G+   + +
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 2863 LR 2864
            LR
Sbjct: 696  LR 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 994  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 1106

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 1107 PPPIITWAK 1115



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 265  PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP I     P    +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 1509

Query: 323  LRVRNTQKSDSGHYTLLAENPNG 345
            L ++N +++D G Y     N  G
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 7/149 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            SH   I+   G +I  EC V+    PT  + W  +  PL      +   D  ++ L + +
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKN 2352

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
             +  D+G Y C A N  G       L      +I  + + P+    +  VE+   +   +
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE---NISVVEKNSVSLTCE 2409

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEG 2926
                 +P   + K  W + ++   +++ G
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSG 2438



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   + W+ +G P++     +     G   L IL A  ++ G Y C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2067 VKV 2069
            VKV
Sbjct: 2661 VKV 2663



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 3124

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 3242 QVPPSVAGAEI 3252



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 3439 SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 3494

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 3535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 4100 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSS 4157

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 4158 STSTKLTVHVPPR--IRSTEGH 4177



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 4194 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 4251

Query: 997  ANLTI 1001
             +LT+
Sbjct: 4252 VSLTV 4256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 6/142 (4%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
            Q  + +    L I++    DEG Y+C+A +SAG         V++P     +P      +
Sbjct: 474  QYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVP-----NN 528

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V  G+ A     I S +   + W R    +    +   I    N  L + +    D G
Sbjct: 529  VTVTPGERAVLTCLIISAVDYNLTWQRNDRDV-RLAEPARIRTLANLSLELKSVKFNDAG 587

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C  ++  G    S  L V+
Sbjct: 588  EYHCMVSSEGGSSAASVFLTVQ 609



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK ++ W  N + I  S+R     D     L +K   P+D+G Y C A N  G    +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 1798 STL-FVQSKASLQLESQHESALQKIQQLE 1825
            STL ++++   + ++S+   AL  I  +E
Sbjct: 694  STLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 775  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449

Query: 1003 TKKDII 1008
                II
Sbjct: 1450 VPPTII 1455



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 3833 ITQIKSHTVE----ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            IT   SH  E      + +  EC V+    P   + W ++G  L        + D G + 
Sbjct: 2292 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI- 2347

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGM 3937
            L +  ++  D+G Y+C AVN  G    K  +S    P II  ++ P  +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2396



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            P   + WF +G  L      R     G   L IL   E+N+G Y CVATN+ G
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            DV    P+   C       PT+   W+ +G P  +  +V  L   G   L I      DA
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDA 2843

Query: 3766 GEYTCRATNKWG 3777
            G YTC A N+ G
Sbjct: 2844 GRYTCVAVNEAG 2855



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL TL D+ +
Sbjct: 3334 L------NVYVTPTI-RGNKDEAEKLMTLVDTSI 3360



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 3581

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 3685

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 3686 -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3744

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 3745 TWRKDGAVLAGNHARYSILENGFLHI---QSAH 3774



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L IA V+  D+G YT +A N AG +  S  +TV 
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAI 4187



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP + Q P N  +  G  A     +       +TW +N + +  +    I T  N  +L 
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLE 577

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
           +++ + +D+G Y  +  +  G    S +L V+ P +  V  +   +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSF 623



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 790  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 847  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 897  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 951

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 952  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 1236

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQE 1260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFET-RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            VY PP     L +    +    H  T   +  G+P+  + WLK+G  ++A+         
Sbjct: 1635 VYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR--IEA 1692

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
            G   L+++S    D G+Y C A S  G  E K  + V     IE
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 1736



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 2039 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDID 2097

Query: 860  IRV 862
            +RV
Sbjct: 2098 LRV 2100



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 2099 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 2156

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              + ++     +QD+G YTC A +  G  E
Sbjct: 2157 SVLKIE--DAQVQDTGRYTCEATNVAGKTE 2184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R+  NI  VE  +V L C     G     + WF +G P+   +  R         L L+ 
Sbjct: 2391 RSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQ 2446

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
               ED+G YTC   N  GE      L V+    ++ E+
Sbjct: 2447 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN 2484



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W+KDG P++ S+ +  I + G + L +M    EDAG YT    N  GE
Sbjct: 2414 PLPSITWFKDGWPVSLSNSV-RILSGGRM-LRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P+  + WYKDG+P+ +   +    N G+ +L I   +  D G YT  A N  GE
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGE 2753



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG P+ +S ++      G   L I    V DAG YTC A N  G+ +   ++ ++
Sbjct: 2811 WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+ N++EG     EC    +  P +T  W+ NG+ I          D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPVIT--WYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2177 EDSGTYMCKATNKLG 2191
             D+G Y+C+A N  G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 3147 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
               L +      DSG YTC A +  G A+
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 3449 KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 3504

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3536



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 3769

Query: 325  VRNTQKSDSGHYTLLAENPNG 345
            +++   +D+G Y  +A N  G
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAG 3790



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 4106 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162

Query: 860  IRV 862
            + V
Sbjct: 4163 LTV 4165



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 4419 CVATNEAGVVERS 4431



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 4427 VVERSMSL 4434



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 4433 SLTLQSPPIITLEPVE 4448



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKI 876



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + W KD R +  S+ +T F N G + + I+S  + DAG Y C A N+ G
Sbjct: 1952 ITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +  A  +DTG YT  A
Sbjct: 2029 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVA 2085

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 3261 GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTS 4160

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 4161 TKLTVHVPPRIRSTEGHYTVNENSQAI 4187



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP--FATGSR 3743
            T  D    PP   +++ +N+ V  G      C +    D    + W  N R    A  +R
Sbjct: 512  TFFDVSEPPP--VIQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPAR 567

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            + TL +   ++L++  +   DAGEY C  +++ GS+  +  +T
Sbjct: 568  IRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 700  EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 754

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 755  GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 798



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 1236

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTV 1264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++ +LL SG    T  + G + +DI      
Sbjct: 1929 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNRLL-SGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1985 DAGIYKCVAINSAG 1998



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 1176 KPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +P      S+P    V+ GK+I LEC ++ +  PT  V W  +G  +      +   +  
Sbjct: 2289 RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGH 2346

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
             + L  IH   +DTG Y   AVN  G       + V     I+ + ++ + I  ++
Sbjct: 2347 ILQLKNIHV--SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+ E QS    C +   P P   + W+ +G+ LQ    +   +   F  L I  V    +
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPE--ITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545

Query: 1915 GEYTCKAINNLGQAVSSIRLNV 1936
            G YTC A +  G    S  LNV
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNV 2567



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P D+ +  NS     C       ++  + WF +G PL +   ++ +   G   L+I    
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPAT--ITWFKDGTPLESNRNIRILP--GGRTLQILNAQ 2637

Query: 3624 QRDAGLYTCKATNRHGE 3640
            + +AG Y+C ATN  GE
Sbjct: 2638 EDNAGRYSCVATNEAGE 2654



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 51/193 (26%), Positives = 78/193 (40%), Gaps = 41/193 (21%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            P+  + W+ +G+P  +   V+   + G   L I      D G YTC A+N          
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASN---------- 2749

Query: 3785 ITCSAKRDIVLESQLPQGMSGEKIKE----LERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            I    + D  +  Q+P   S +K+ E    L+ GR  +A  ++ I++ P           
Sbjct: 2750 IAGEDELDFDVNIQVPP--SFQKLWEIGNMLDTGRNGEA--KDVIINNP----------- 2794

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
                  +   C       P L   WY++G  L S  +   +   G V L I     ED+G
Sbjct: 2795 ------ISLYCETNAAPPPTLT--WYKDGHPLTSSDKV-LILPGGRV-LQIPRAKVEDAG 2844

Query: 3901 EYICRAVNDFGED 3913
             Y C AVN+ GED
Sbjct: 2845 RYTCVAVNEAGED 2857



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+I++   S + E    P       + W+ +G PL +  +V  +   G  +L+I      
Sbjct: 2788 DVIINNPISLYCETNAAP----PPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVE 2841

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            DAG YTC A N  GE ++   ++V
Sbjct: 2842 DAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T+  T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 3354 TLVDTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 3409

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3519

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 3520 ILKV-------LEPPHINGSEEHEEI 3538



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 4438 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4494

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 4495 YIADAQ---KEDTSEFECVARNLMGS 4517



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P+     KN   T G  V +  + T    P  ++ W  N   +   HR++ T D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG- 664

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
               L I  A  +D G Y C A+N+ G     S+++
Sbjct: 665  --TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI W  N   +    R+++TSD    TL + +   +D+GIY C A N  G    +ST
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 3001 V 3001
            +
Sbjct: 696  L 696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 756

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 757  -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 794  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 854  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICV 1339

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 1340 AVNEAGTTERKYNLKV 1355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAG 1345



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   P  + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNF---PNEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 1493

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 1471 VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 1527

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 1528 SNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915

Query: 1136 ETRSSID 1142
                S++
Sbjct: 1916 HEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G  + LE  +  +  PT  V W  +G P+ +    +   D G++ L +   +  DTG
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTG 2359

Query: 2049 TYMCKATNAVG 2059
             Y+C A N  G
Sbjct: 2360 RYVCVAVNVAG 2370



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 8/144 (5%)

Query: 3962 DDLYDVDKKQPPRFVTQIQS--QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            D  YD+    PP  +   +S    S+VE  +    C+ +  G P   + WF +G P+   
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLS 2430

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
            N    +   G   +       ED+G+Y C   N  G +     +     P IV ++ L +
Sbjct: 2431 NSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-E 2487

Query: 4080 HMKSIEKIREMEASWQVTPEQVVE 4103
             +K  EK + +  + +VT   V E
Sbjct: 2488 DVKVKEK-QSVTLTCEVTGNPVPE 2510



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + W+ +G  L+S    R     G   L IL    +++G Y+C A N  G+ 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 1929 VSSIRLNV 1936
            +    + V
Sbjct: 2656 IKHYEVKV 2663



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV 3622
            +P ++ +  N++   EC    +  +S+   W+ +G+PL +   V    + G   L+I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 3623 YQRDAGLYTCKATNRHGE 3640
               D G YTC A+N  GE
Sbjct: 2736 QISDTGRYTCVASNIAGE 2753



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDL 1509
            PK ++  +    +  EC+   +  ++L   W+K+GQP+        I   G+  L I + 
Sbjct: 2681 PKEVKIKVNNT-LTLECEAYAIPSASLS--WYKDGQPLKSDDHVN-IAANGHT-LQIKEA 2735

Query: 1510 IAEDSGIYTCRAVNLVGTDEV 1530
               D+G YTC A N+ G DE+
Sbjct: 2736 QISDTGRYTCVASNIAGEDEL 2756



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/120 (30%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            EDS +Y  R  V   +  A    + L     +   +SA  EC     P P  R  W  +G
Sbjct: 2856 EDSLQYDVRVLVPPIIKGAN---SDLPEEVTVLVNKSALIECLSSGSPAP--RNSWQKDG 2910

Query: 1885 K-VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            + +L+  H    SN      L IL     D G Y C A N  G A     LNV    S+I
Sbjct: 2911 QPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2967



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 2986 CEVSGFPPPDL--SWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 3041

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 3042 GESKKKFSLTVYVPPS-IKDHDSES 3065



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 8/151 (5%)

Query: 2194 VNTCTLKVAGHRNI-ILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV---TELR 2249
            +NT TL V G R + I+  +  +G E       Q   ++ +       PP      +E  
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESL 3066

Query: 2250 GTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
               +V EG +   EC+   V  P   I +Y NG+ +  +    I  D G + L I+    
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
             D G+Y  +AIN  G       + V    SI
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 3447 VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 3502

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 3503 KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 3674

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 3675 RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 3722



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 3979

Query: 724  AVLHV 728
              LHV
Sbjct: 3980 VTLHV 3984



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 14/133 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 4217 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 4268

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 4269 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 4322

Query: 3219 SGEYVCRAYNKYG 3231
            SG YVC A N  G
Sbjct: 4323 SGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W +N + +    R+R T D    TL I +    DAG+Y C A N AG
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V    PV  +C+    G+P   I W+ + R   +GS   T  + G I +DI+     
Sbjct: 1929 NETVLVSNPVQLECKA--AGNPVPVITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3764 DAGEYTCRATNKWGS 3778
            DAG Y C A N  G+
Sbjct: 1985 DAGIYKCVAINSAGA 1999



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 3826 VSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNEQ--PIKLNTNTLIVP 3015

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            G  +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN+ GE+   
Sbjct: 2990 GFPPPDLSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 3108 ILADGQMLH 3116



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 2996 LSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 1003 TKKDI 1007
                I
Sbjct: 3054 VPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 724  AVLHVTPRATIERTSQHPETL 744
              L+V    TI       E L
Sbjct: 3332 FNLNVYVTPTIRGNKDEAEKL 3352



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 1791 LGE 1793
             G+
Sbjct: 3605 AGD 3607



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 3712 PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 3768

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 3769 HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 3887

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 3888 TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 3936

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 3937 LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 3985



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 3952

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 3993



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 4260 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 4312

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  +T +   ++   G      C       P +   W  N   I   HRYR T D   
Sbjct: 609  QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDMFIVGSHRYRMTSD--- 663

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
              L I     +D+G Y C A+N  G      TL+
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 1273 TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVT 1329

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 1330 PYDNGEYICVAVNEAGTTERKYNLKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 3510 MKV 3512
            +KV
Sbjct: 1353 LKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAG 1438



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 1671 SKKSI 1675
               S+
Sbjct: 1917 EPPSL 1921



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1946 GNPVPVITWYKDN-RLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L  +T +EG  I      E  G P   + W K G  +   S        G   L +    
Sbjct: 2203 LTQLTVIEGNLISL--LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE 2260

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
              D+  Y+C A +  G A+ +  L V  R TI  +  HP
Sbjct: 2261 KSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHP 2299



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG  + L  +      PNL   W K G  + T +  +     G   L I+     D+ 
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLI--WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2265

Query: 2714 IYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            +Y+C A+N+ G A    ++++  R  +     HP  +
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W+++G P+  +  +  + D G++ L +K ++  D+G Y C A+N  G     
Sbjct: 2318 GIPPPTVTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2375

Query: 1798 STLFVQSKASL 1808
              L V +  S+
Sbjct: 2376 YDLSVHAPPSI 2386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P   + W ++G P+E++  +  +   G   L +     +++G Y+C A NE GE +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 2963 PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GG 3017

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 3430

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 3431 FAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 3791



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 3744 ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3801

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 3802 VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 3852

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 3853 YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 4260 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 4312

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 945  WLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            W ++ R V  +  +RI T  N   ++L +KSV  +DAG Y C   +  G +  S  LT+ 
Sbjct: 553  WQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 1002 -VTKKDIIAESQHPGGLEKIQYLEDASRYSK 1031
               K  ++ ++Q   G  ++  +  A+ Y K
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPK 640



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    PK+ ++   G  V   C          K+ W  N   +   HR+R   D     
Sbjct: 612  PKVTVMPKN-QSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG---T 665

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L I +   +D+GIY C A N  GTD+ +  L
Sbjct: 666  LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            +T+T+   +   + +  + A    Q  + + V   P+  R   +++   G  V + C  Q
Sbjct: 1137 ITETRTSDSGMYLCVATNIAGNVTQAVK-LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G     + W   G  +        +     +++D  +  P D+G+YTC ATN  G   
Sbjct: 1196 --GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT--PSDAGIYTCVATNIAGTDE 1251

Query: 1396 TSCALRV 1402
            T   L V
Sbjct: 1252 TEITLHV 1258



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            +L C +E  G P+  + W+ +   VT  S  +T  + G + L +  AT  D G Y+ +A+
Sbjct: 1379 NLFCEVE--GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAI 1434

Query: 1256 NHLGSAHTSAIVRVIERSDIV-TDTQNEQAI 1285
            N  G++     + V+    I+ T+  NE ++
Sbjct: 1435 NIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 1465



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   + WYKD R ++ S+ +T   N G + ++I   +  DAG Y   A+N  G      
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 859  SIRVAARSTVT 869
            S++V    +++
Sbjct: 2005 SLQVHVAPSIS 2015



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ID  V + P  +   +++ +V+  Q V   C+ + +    L   W K+G P+ +      
Sbjct: 2096 IDLRVYVPPNIMGEEQNV-SVLISQAVELLCQSDAIPPPTLT--WLKDGHPL-LKKPGLS 2151

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            I +   V L I D   +D+G YTC A N+ G  E
Sbjct: 2152 ISENRSV-LKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3694 PPRFTVE-IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP    E   +++ V E   V   C V   G+P   I W  +G+P       H ++   F
Sbjct: 2477 PPHIVGENTLEDVKVKEKQSVTLTCEV--TGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2534

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I  +     G YTC A++  G
Sbjct: 2535 --LQITNVQVPHTGRYTCLASSPAG 2557



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  + E    P+  + W+K+G  L +   +    +    TL I   +  D+G YTC A+N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASN 2749

Query: 2722 LLGE 2725
            + GE
Sbjct: 2750 IAGE 2753



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 2/72 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KDG+P+        F + G + L I +  + D G Y C A N  G A   
Sbjct: 2898 GSPAPRNSWQKDGQPLLEDDH-HKFLSNGRI-LQILNTQITDIGRYVCVAENTAGSAKKY 2955

Query: 997  ANLTIVTKKDII 1008
             NL +     +I
Sbjct: 2956 FNLNVHVPPSVI 2967



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 14/146 (9%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYVALDLLSVY 1376
            N+  V    + L C +   G     + W  N +PIK  T     P        L ++   
Sbjct: 2973 NLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTNTLIVPGGR----TLQIIRAK 3026

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              D G YTC A NQ GE+    +L V       ++      L  +   E TS      + 
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTS----VSLE 3080

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHV 1462
             ES  + P  +T  K+   + E  HV
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHV 3106



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 3073 EGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 3129 VCRAINVAG 3137



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W +N K IE+S  +      G   + I+  +  D G Y C ASN+ G+
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 3318

Query: 146  CTARNQYGE 154
            C A N  GE
Sbjct: 3319 CVATNPAGE 3327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 3357 DTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 3412

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 3413 CVASNRAGVDNKHYNLQV 3430



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 3556 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613

Query: 860  IRV 862
            +RV
Sbjct: 3614 VRV 3616



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 3728 KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 3782

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  +G+ ++   R + ++      L+I  V   DAG YTC A N  G ++ S KL V
Sbjct: 4110 ITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 4364 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 4418

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 4419 CVATNEAG 4426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPP   VP  +VT   G +      I    D    + W +N + +  +     I     +
Sbjct: 519 PPPVIQVP-NNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEP-ARIRTLANL 574

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQ 739
           SL++ S+   D+GEY C   S  G +     L V   P+ T+   +Q
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 702  PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 757

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 758  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 799



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 1007 NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 1063

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 1064 VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 1118

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 1119 LISPFSPRH 1127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 1253

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQE 1277



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +E  P P   + WY +   +      +T N+     L +     ED+G Y+CKAIN  
Sbjct: 1382 CEVEGTPSPI--IMWYKDNVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIA 1437

Query: 1926 GQAVSSIRLNVQSKESII 1943
            G +     ++V    +II
Sbjct: 1438 GTSQKYFNIDVLVPPTII 1455



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1844 PRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            P  I   N P ++S    +    EC+++  P P+  + W+ +GK L  G       D G 
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRG- 1507

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L +      D G Y C   N  G+    I+L +    SI
Sbjct: 1508 QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 1548



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+     +   + G   L+I+ A   
Sbjct: 1650 NKQVVIAHSLTLECKAA--GNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEI 1705

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 1838 VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 1894

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 1895 RYTCVATNAAGE 1906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 1912

Query: 2199 LKV 2201
            L V
Sbjct: 1913 LHV 1915



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 2001 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 2057

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 2058 GLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 2109



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V   +PV LE     +  P++   W  +G PV            G + L +  A   DTG
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLT--WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTG 2079

Query: 2049 TYMCKATNAVGE 2060
             Y C A NA GE
Sbjct: 2080 RYTCVAVNAAGE 2091



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 2034 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVN 2087

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 2088 AAGEKQRDIDLRV 2100



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  + + Q+ + L+  +  +  CQ   +  P +   W  +G PLL K   +   +   +
Sbjct: 2103 PPNIMGEEQNVSVLIS-QAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENRSVL 2159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V  +D+G Y C ATN+ G  E    +     P I
Sbjct: 2160 KIEDAQV--QDTGRYTCEATNVAGKTEKNYNVNIWVPPNI 2197



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G ++ LEC +Q +   T  V W  +G P+          E     L L +++  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSD 2357

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            +G Y C A N  G       L V A   +I   + P  +  ++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P   + W ++G P+  SN +  +   G   L +     ED+G YTC   N  GE
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P ++ +  N SA  EC  +     + R  W  +G+PLL     K +++    IL+I    
Sbjct: 2879 PEEVTVLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQ 2934

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQV 3649
              D G Y C A N  G A     L V
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNV 2960



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/71 (33%), Positives = 31/71 (43%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N   IE S+ L      G   L +      DSG YTC A N  G+A   
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 1798 STLFVQSKASL 1808
              L +Q   S+
Sbjct: 3237 YFLSIQVPPSV 3247



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 4165 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 4222

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 4223 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 4426


>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-174L6 on chromosome 1. ).
          Length = 5635

 Score =  129 bits (312), Expect = 2e-28
 Identities = 107/384 (27%), Positives = 161/384 (41%), Gaps = 35/384 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  ++ A  E    G P P   W ++  P+      +    S   IL I    + D   +
Sbjct: 2884 VLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRILQILNTQITDIGRY 2941

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGT 4540
              VAEN  G+AK   NL V           VPPS     ++N+ V     + L  +V+G 
Sbjct: 2942 VCVAENTAGSAKKYFNLNVH----------VPPSVIGPKSENLTVVVNNFISLTCEVSGF 2991

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P D+ WLKN + ++ +    I+   G  TL I+ A   D G+Y C+AIN AGE++    
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V +P       P  K  ++     E L    V EG ++   C+    P P + WYK  
Sbjct: 3050 LTVYVP-------PSIKDHDS-----ESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3097

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            ++I  S + ++   AD   L I +A   D G Y C A N AGR      L V  P   + 
Sbjct: 3098 RMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155

Query: 4721 LPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                 P R+++V     P       T    PTI WL+    I  +   ++      + L 
Sbjct: 3156 -----PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVE 4803
            I  +   D+G +TC A+   G+ +
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQ 3234



 Score =  119 bits (287), Expect = 2e-25
 Identities = 103/380 (27%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 1148

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 1149 LCVATNIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 1257 HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 1305

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   D   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 1306 EL--TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               +T   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 1364 KEQVT---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKL 1418

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 1419 FRATPEDAGRYSCKAINIAG 1438



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/371 (27%), Positives = 155/371 (41%), Gaps = 39/371 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + W R +  ++ +   +I T +  S L ++ V   D+  +  +  + GG++  S  L V+
Sbjct: 551  LTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E          PP  T+  +N + T G  V +    TG     + W  N   +    R +
Sbjct: 610  E----------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYR 659

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             +  DGT  L I  A P+D+G Y C+A NSAG                DK     +   A
Sbjct: 660  -MTSDGT--LFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEA 701

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P +++    + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+
Sbjct: 702  P-KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLK 758

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I E    D GDY CVA N AGR T    L V  P      PA     D+ +  G      
Sbjct: 759  IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLP 813

Query: 4742 TQITSKIKPTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              +    +PTI+W R +   I   P     I +     L I N +  D GT+ C A    
Sbjct: 814  CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 4800 GQVETSAKLVV 4810
            G++++   + V
Sbjct: 874  GKIQSETTVTV 884



 Score =  115 bits (276), Expect = 5e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 4237

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 4238 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 4287

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 4288 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 4344 YVKEP-------PVFKG-DYPSNWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 4388

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 4389 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 4441

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 4442 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 4497

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 4498 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score =  113 bits (271), Expect = 2e-23
 Identities = 103/405 (25%), Positives = 158/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 1227

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 1282

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + EDGT  L+I    P D+G+Y CVA+
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAV 1341

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDK---------------EQVTNVSVLLNQLTNLFCEVEG 1386

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 1387 TPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P      ++ V   +    + Q+     P I W ++G  L    P
Sbjct: 1445 NIDVLVPPTIIGTNFP-----NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 1500 NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  110 bits (264), Expect = 1e-22
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI-VPGGRTLQI 3022

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N+ G +K   +L V           VPPS     + +   VNV
Sbjct: 3023 IR-AKVSDGGEYTCIAINQAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 3071

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 3129

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 3174

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 3235 KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  109 bits (261), Expect = 3e-22
 Identities = 100/368 (27%), Positives = 151/368 (41%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 3271 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 3330

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         TL   ++N+        + + TGT P  + WLKNG  
Sbjct: 3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI--------ECRATGTPPPQINWLKNGLP 3382

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 3383 LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 3438

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 3439 ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 3486

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 3487 HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 3541

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 3542 VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 3598

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 3599 CLASSPAG 3606



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 3054 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI--LAD 3111

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 3112 GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 3161

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 3267

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 3268 CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L  +V         + + T    P I WL+ G  +P
Sbjct: 3328 EDRIFNLNVYVTPTIRGNKDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLP 3384

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 3385 LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 3420



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/407 (25%), Positives = 164/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 4043

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 4093

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMA 4150

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 4151 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 4194

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 4195 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 4250 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 4301

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+    + VK
Sbjct: 4302 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346



 Score =  106 bits (255), Expect = 2e-21
 Identities = 91/382 (23%), Positives = 165/382 (43%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P++ W ++  P+K + + +I     K  ++  Q    D   +  VA +  G
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAG 1719

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWL 4548
              +    + V          +VPP+     +     V    L+ LD  VTG+ P  + WL
Sbjct: 1720 EKEIKYEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWL 1769

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P  
Sbjct: 1770 KDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP-- 1825

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  K++         L +++V + + +   C   G P P++ W K D+ +  ++ 
Sbjct: 1826 -----PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ- 1871

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              +   +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L 
Sbjct: 1872 GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LN 1929

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            + V+    P Q + +      P I W ++  L+  +     ++ G   ++ I +    D 
Sbjct: 1930 ETVLV-SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDA 1986

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A  +AG  E    L V
Sbjct: 1987 GIYKCVAINSAGATELFYSLQV 2008



 Score =  105 bits (253), Expect = 3e-21
 Identities = 122/485 (25%), Positives = 195/485 (40%), Gaps = 59/485 (12%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            ++ G P P +SW + + P+    K +       G  +L I +    D GEYTC A NQ G
Sbjct: 2987 EVSGFPPPDLSWLKNEQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 154  EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
            E+      +VY+ P                   S ++E ++                  Y
Sbjct: 3043 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITW--------Y 3094

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
             NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 3095 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 3152

Query: 268  IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
            I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 3153 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIA 3212

Query: 327  NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 3213 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 3253

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                         D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 3254 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREG 505
            +  L I     SD+G  TCVA N +GE      LNV     +   K   E+  TL     
Sbjct: 3302 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTL---VD 3357

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              + +  RA GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A
Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVA 3415

Query: 566  QNVAG 570
             N AG
Sbjct: 3416 SNRAG 3420



 Score =  105 bits (252), Expect = 4e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 3420

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 3421 VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 3471 RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 3526

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 3527 -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 3573

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 3574 -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 3629

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 3687

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 3688 ANYTCVASNIAGKTTREFILTV 3709



 Score =  105 bits (251), Expect = 5e-21
 Identities = 101/395 (25%), Positives = 161/395 (40%), Gaps = 35/395 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP    + Q   V   +      + D  P P + W ++  P+   P   I     +S+L 
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTS 4527
            I    V+D+  +   A N  G  + + N+ +           VPP+   + +   + V  
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW----------VPPNIGGSDELTQLTVIE 2210

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G L+ L  + +G  P ++ W K G  V  D   ++    G   L I  A   D+  Y CV
Sbjct: 2211 GNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCV 2270

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG A+ +    V +  T       T + + P EI       IV  G++I   C++ 
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPT------ITNSGSHPTEI-------IVTRGKSISLECEVQ 2317

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PTV W K G  LIK +K  ++    + + L++      D G Y CVA N AG    
Sbjct: 2318 GIPPPTVTWMKDGHPLIK-AKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2374

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V  P     +       +I V E        + +    P+I W ++G  +  +  
Sbjct: 2375 KYDLSVHAPPSI--IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNS 2432

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +++  G   +L +  T  ED G +TC    AAG+
Sbjct: 2433 VRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score =  104 bits (250), Expect = 7e-21
 Identities = 109/409 (26%), Positives = 167/409 (40%), Gaps = 41/409 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 850

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 851  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 902

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 903  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 959

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 960  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 1003

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSS-AKFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYAK 1061

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +   L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V
Sbjct: 1122 PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score =  104 bits (250), Expect = 7e-21
 Identities = 96/377 (25%), Positives = 155/377 (41%), Gaps = 34/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P  +W + +  +  +P   + +  +   L I +V ++D   +  VA N  GT   +
Sbjct: 916  GNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT 972

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             ++VV           V P+     Q ++   G  V L  K +G     V W K G+ + 
Sbjct: 973  TSVVVH----------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                      DG+  L ++    ++SG+Y C A N+AG A+   +  V +       +P+
Sbjct: 1023 TSSAKFSAGADGS--LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYV-------RPR 1073

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT- 4674
                       +P++  ++A G+ +   C++   P P + W K  +LI P   F    T 
Sbjct: 1074 VFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITWAKETQLISP---FSPRHTF 1129

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +++I+E    D G Y CVA N AG VT A KL V  P +    P     + + V  
Sbjct: 1130 LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQV 1184

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            GQ             P I W + G+ +    D +      +  L I      D G +TC 
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCV 1242

Query: 4795 ATTAAGQVETSAKLVVK 4811
            AT  AG  ET   L V+
Sbjct: 1243 ATNIAGTDETEITLHVQ 1259



 Score =  104 bits (250), Expect = 7e-21
 Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKE 1817

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 1818 FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 1868 NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 1919

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK ++L+  S    M+  
Sbjct: 1920 SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFL 1970

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1971 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 2025

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +    DTG +TC 
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSAQISDTGRYTCV 2084

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 2085 AVNAAGEKQRDIDLRV 2100



 Score =  104 bits (250), Expect = 7e-21
 Identities = 102/369 (27%), Positives = 147/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W + +  I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 3237 YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 3286

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 3287 IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 3339

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +  L D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 3340 PTIRGNKDEAEKLMTLVDT------SINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 3391

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 3392 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 3448

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3506

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 3507 IASNEAGEV 3515



 Score =  104 bits (249), Expect = 9e-21
 Identities = 101/398 (25%), Positives = 164/398 (41%), Gaps = 40/398 (10%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVF 4474
            KM    V      + E +  G P+P+I WY++N  +  S      TF  +  +I I    
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSM---TFLNRGQIIDIESAQ 1982

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + D+ ++  VA N  G  +   +L V           V PS + +   V V     VRL+
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH----------VAPSISGSNNMVAVVVNNPVRLE 2032

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +  G     + WLK+G  V     N +    G   L +  A   D+G+Y CVA+N+AGE
Sbjct: 2033 CEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             + D +  V +                PP I+   ++  V   QA+E  C+    P PT+
Sbjct: 2092 KQRDIDLRVYV----------------PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135

Query: 4655 QWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             W K G  L+K      +S + +   L+I +A  +D G Y C A N AG+      + + 
Sbjct: 2136 TWLKDGHPLLKKP---GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHE 4772
             P    N+     L  + V EG       + +    P + W ++G+ ++ ++     I  
Sbjct: 2193 VP---PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS 2249

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G    L I    + D   ++C A+  AG  +    L V
Sbjct: 2250 GGRQ-LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286



 Score =  102 bits (245), Expect = 3e-20
 Identities = 96/389 (24%), Positives = 155/389 (39%), Gaps = 31/389 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  +   R E E  G P P + W ++  P+ +  +  +   S   IL +    + D+  +
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRY 2081

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G  +   +L V           VPP+     QNV+V   Q V L  +     
Sbjct: 2082 TCVAVNAAGEKQRDIDLRV----------YVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  + WLK+G  +       I E      L I +A  QD+G+Y C A N AG+   +   
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNVAGKTEKNYNV 2189

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             + +P       P    +       + L    V EG  I   C+  G P P + W K   
Sbjct: 2190 NIWVP-------PNIGGS-------DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +      ++   +    L+IS A   D   Y CVA N AG       L+V       N 
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
             +     +I+V  G+    + ++     PT+ W+++G  + +    +++ EG+  +L + 
Sbjct: 2296 GSHPT--EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQLK 2351

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            N +  DTG + C A   AG  +    L V
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380



 Score =  101 bits (243), Expect = 5e-20
 Identities = 101/380 (26%), Positives = 148/380 (38%), Gaps = 35/380 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 1006 GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPGG-EESGEYVCTATNTAGYAKRK 1063

Query: 4496 ANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V  + R    + G+           ++V +G+ V L  +V    P  + W K  + 
Sbjct: 1064 VQLTVYVRPRVFGDQRGLSQDK----PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 1119

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P          G+  + I E    DSG Y CVA N AG      +  V          
Sbjct: 1120 ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV---------- 1167

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S 
Sbjct: 1168 ------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIV 4731
               + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V
Sbjct: 1222 P--DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 1279

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                Q  +F        KPTI+WL  G  L    P   ++ +G   +L+I +    D G 
Sbjct: 1280 A--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGE 1335

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A   AG  E    L V
Sbjct: 1336 YICVAVNEAGTTERKYNLKV 1355



 Score =  101 bits (241), Expect = 8e-20
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 3912

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 3970

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 3971 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 4013

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 4014 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 4071

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 4072 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 4126 RVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 1242 VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 1293

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 1294 PKPTIKWLHNGRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 1353 LKVH----------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 1400

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 1453

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 1506

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 1507 GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 1561

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 1562 NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 1619

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 1620 VANVAGTAEKS 1630



 Score =  100 bits (239), Expect = 1e-19
 Identities = 106/423 (25%), Positives = 169/423 (39%), Gaps = 31/423 (7%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKK-MQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T +   A  +ER + G      P I  +  ++  +V E +      E  G P+P I W++
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK 2515

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRR 4505
            +  P++   D   H  S    L I  V V  +  +  +A +  G    S +L V      
Sbjct: 2516 DGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
             G G    P      ++V V       L  +     P  + W K+G  ++ +   +IL  
Sbjct: 2574 AGVGSDGNP------EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL-- 2625

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             G  TL IL A   ++G+Y CVA N AGE     E  V +P   +K         +P E+
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL-SPKEV 2684

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
                K K+      +   C+    P  ++ WYK  + +K   +  ++  A+ +TL+I EA
Sbjct: 2685 ----KIKV---NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA--ANGHTLQIKEA 2735

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-------VVYEGQPA 4738
               D G Y CVA N AG   +   + +  P     L  +  + D         V    P 
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +  +   PT+ W ++G   P T   +++      VL I     ED G +TC A   
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNE 2853

Query: 4799 AGQ 4801
            AG+
Sbjct: 2854 AGE 2856



 Score =   99 bits (238), Expect = 2e-19
 Identities = 82/299 (27%), Positives = 123/299 (41%), Gaps = 40/299 (13%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P    +  G     + ++ G P P VTW K+G  LI +   EI+    H  L+++N   S
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGH-ILQLKNIHVS 2356

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            D+G Y  +A N  G       L+V +P  S + + RS                       
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHRS----------------------- 2392

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ + V +   V+        C  +G P P +TWF +   +    + +IL   SG   L 
Sbjct: 2393 PENISVVEKNSVS------LTCEASGIPLPSITWFKDGWPVSLSNSVRIL---SGGRMLR 2443

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +   T+ D+G  TCV RN +GE      L+V+    +V    +E    + V+E + V L 
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE---DVKVKEKQSVTLT 2500

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG P+    +   H   G   L I   +      Y C A + AG
Sbjct: 2501 CEVTGNPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 35/375 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E E  G P P + W ++  P+  +   +I       IL ++ + V D+  +  VA N  G
Sbjct: 2313 ECEVQGIPPPTVTWMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT---LTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
                  +L V            PPS      + +N++V     V L  + +G     + W
Sbjct: 2371 MTDKKYDLSVH----------APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITW 2420

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G  V   + N +    G   L +++   +D+G+Y CV  N+AGE R      V +P 
Sbjct: 2421 FKDGWPVS--LSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP- 2477

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                  P     N        L+D  V E Q++  +C++ G P+P + W+K  + ++  +
Sbjct: 2478 ------PHIVGENT-------LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               +   +    L+I+       G Y C+A + AG  + +  L V        + +    
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
             D+ V    P     +  S    TI W ++G  +    + +++  G    +L  N  E++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL--NAQEDN 2640

Query: 4788 TGTFTCRATTAAGQV 4802
             G ++C AT  AG++
Sbjct: 2641 AGRYSCVATNEAGEM 2655



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 95/380 (25%), Positives = 157/380 (41%), Gaps = 34/380 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E +  P P + WY++  P+ +S    I       +L I +  VED+  +  VA N  G  
Sbjct: 2800 ETNAAPPPTLTWYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857

Query: 4493 KCSANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                ++ V+     +G    +P       + V V   +   ++   +G+      W K+G
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLP-------EEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2910

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            + +  D  +K L       L IL     D G+Y CVA N+AG A+               
Sbjct: 2911 QPLLEDDHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAK--------------- 2953

Query: 4612 PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             K      + PP +I P  + + V     I  +C++ G P P + W K ++ IK +    
Sbjct: 2954 -KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +       TL+I  A   D G+Y C+A N AG       L V  P    +  + + L  +
Sbjct: 3013 I--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-LSVV 3069

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG     + +  +   P I W + G +I E+   +++ +G   +L I      DTG 
Sbjct: 3070 NVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQ 3127

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + CRA   AG+ + +  L V
Sbjct: 3128 YVCRAINVAGRDDKNFHLNV 3147



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 88/301 (29%), Positives = 127/301 (42%), Gaps = 37/301 (12%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 1051

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 1052 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 1090

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 1091 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 1143

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 579  Y 579
            +
Sbjct: 1257 H 1257



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF 4137

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 4138 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 4184

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 4185 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 4241

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 4242 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 4286 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKAIG 4341

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 4394

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 4395 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 88/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 1227

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 1268

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 1269 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 1318

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
             G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ + ++V  
Sbjct: 1319 DGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVTNVSVLL 1374

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 1375 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCK 1432

Query: 565  AQNVAGST 572
            A N+AG++
Sbjct: 1433 AINIAGTS 1440



 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 96/388 (24%), Positives = 160/388 (41%), Gaps = 36/388 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E        E  G PLP I W+++ +P+  S   +I   S   +L + Q  +ED+  +
Sbjct: 2398 VVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRMLRLMQTTMEDAGQY 2455

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTG 4539
              V  N  G          EE++  G   +VPP      T ++V V   Q V L  +VTG
Sbjct: 2456 TCVVRNAAG----------EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                ++ W K+G+ +Q D  + I+   G   L I       +G+Y C+A + AG      
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
               V +      P      ++  PE      D  V         C+    P  T+ W+K 
Sbjct: 2564 SLNVFV-----SPTIAGVGSDGNPE------DVTVILNSPTSLVCEAYSYPPATITWFKD 2612

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP---D 4716
               ++ ++  ++       TL+I  A  ++ G Y CVA N AG +    ++KV  P   +
Sbjct: 2613 GTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2670

Query: 4717 QADNL-PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
            + D   P L+P +++ +        + +  +    ++ W ++G   P   D  +    N 
Sbjct: 2671 KGDLWGPGLSP-KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ--PLKSDDHVNIAANG 2727

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              L I      DTG +TC A+  AG+ E
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDE 2755



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 64/209 (30%), Positives = 88/209 (42%), Gaps = 8/209 (3%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYP 421
            +   QY    +    EER       L P  +      +D  V E +     C VTG P P
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            E+TW  + + +++D  H I+   SG   L ITNV +  +G  TC+A + +G  +    LN
Sbjct: 2510 EITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V     +           + V    P  L   A   P   ITW KDG P+  N  +RI  
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2626

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G  TL I  A+  +A  Y C A N AG
Sbjct: 2627 --GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 3896

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 3951

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 4006

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 4007 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 4065 GTALGKIKL 4073



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 99/397 (24%), Positives = 159/397 (40%), Gaps = 41/397 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N  V  
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1934

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+ + +        L       + I  A   D+G Y+CV
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1992

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1993 AINSAGA----TELFYSL------------QVHVAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++ A   D G Y CVA N+AG    
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 2095 DIDLRVYVPPN-----IMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              +    N +VL I +   +DTG +TC AT  AG+ E
Sbjct: 2150 LSI--SENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 96/379 (25%), Positives = 156/379 (41%), Gaps = 42/379 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W   +  I  S  +++ +  T   L I+    +D+ ++  +A N  GT K +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            + L   E           P   +    + V  G +  ++ K +G  P  V W K   +++
Sbjct: 694  STLRYIEA----------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P   +  L  D    LL I E    D+G Y CVAIN AG A                   
Sbjct: 744  P---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI--------------- 785

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             T    +PP  I+   D  +  G  +   C + G P PT++W + D +   S+ F +S  
Sbjct: 786  -TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 4675 ADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +   T  L I   +  D+G Y C A N  G+  + ++  VT       L  ++P    V+
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK--IQSETTVTVTGLVAPLIGISPSVANVI 902

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQ      T +     P  +W++  A++ + P   +  +G+   L I     +D G +
Sbjct: 903  -EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEY 958

Query: 4792 TCRATTAAGQVETSAKLVV 4810
            TC A+  AG    +  +VV
Sbjct: 959  TCVASNVAGTNNKTTSVVV 977



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 86/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ +  G     + W 
Sbjct: 1533 KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY 1582

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 1583 KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 1638

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   CK  G P P + W K    +K +  
Sbjct: 1639 -----PMIEG-----NLATPLNKQVVI-AHSLTLECKAAGNPSPILTWLKDGVPVKANDN 1687

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             ++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 1688 IRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 1742

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G LI E   F+++  G    L+I      +T
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNT 1800

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTV 1822



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V+G P P+++W  N++ I+ + N  I+    G   L I    +SD G  TC+A N++G
Sbjct: 2986 CEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 3043 ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3101

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 3102 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 3137



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 87/367 (23%), Positives = 146/367 (39%), Gaps = 17/367 (4%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W+++  P++++ + +I        L I     +++  ++ VA N  G       
Sbjct: 2603 PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V       +G +  P   L+ + V +     + L+ +        + W K+G+ ++ D
Sbjct: 2661 VKVYIPPIINKGDLWGPG--LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2718

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                I      +TL I EA   D+G+Y CVA N AGE   D +  + +P +  K      
Sbjct: 2719 DHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
              +         KD I+     I   C+    P PT+ WYK G  L    K   +     
Sbjct: 2777 MLDTGRN--GEAKDVII--NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PG 2829

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L+I  A  ED G Y CVA N AG  ++   ++V  P       +  P  ++ V   +
Sbjct: 2830 GRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP-EEVTVLVNK 2888

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  +   +    P   W ++G  + E    + +   N  +L I NT   D G + C A 
Sbjct: 2889 SALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRILQILNTQITDIGRYVCVAE 2946

Query: 4797 TAAGQVE 4803
              AG  +
Sbjct: 2947 NTAGSAK 2953



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 3607

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 3608 -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 3661

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 3662 LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 3712

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 3713 PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 3762

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 3763 LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 3815

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 3816 IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 3875

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 3876 CTVTNGAGDDKRTVDLTVQ 3894



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 3553 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 3602

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 3603 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 3640

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
              +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 3641 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 3696

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 3697 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 3752 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 4064

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 4065 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 4119

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 4120 VESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 1835 ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 1892

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 1893 AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1947

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1948 PVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 2000



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 13/217 (5%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
            R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  + + I +    KIL+N      L+I    +S++G+  C+A N +G+   +  + V 
Sbjct: 1767 MWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTD 542
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I + 
Sbjct: 1824 VPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSS 1879

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 1880 G--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 49/290 (16%)

Query: 293  PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGY 352
            P   +TWFK+G  L ++    I+      TL++ N Q+ ++G Y+ +A N  G ++    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            + V  P                       + ++    L+P+ VK+  +  +T       +
Sbjct: 2661 VKVYIPP-------------------IINKGDLWGPGLSPKEVKIKVNNTLT------LE 2695

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C     P   ++W+ + + ++ D +  I  N    H L I    +SD+G  TCVA N +G
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAG 2752

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNV----REGE--------PVVLNARAVGTPTP 520
            E      +N+      V P F + +   N+    R GE        P+ L       P P
Sbjct: 2753 EDELDFDVNI-----QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2807

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +TW KDG P+  + ++ I    G   L IPRAK  DA  Y C A N AG
Sbjct: 2808 TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAG 2855



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 52/350 (14%)

Query: 229 RLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGAD 282
           R L  +S   +S+     GE    +S+E   S   V      PPK+   P+N     G++
Sbjct: 569 RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSE 628

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
                  +G P+P++ W  N   ++ S+++ + +     TL ++N    D+G Y      
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY------ 679

Query: 343 PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
             GC+ ++      + T+              +Q  T   IE      AP+ + V  +  
Sbjct: 680 --GCLASNS-----AGTD--------------KQNSTLRYIE------APKLMVVQSELL 712

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L I      D+G 
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGD 769

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TCVA N++G    +  L+V        P F++  + +++  G  V L     G P P I
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI 824

Query: 523 TWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            W++ D +PI   P  +   +      L I    ASD   Y C A+N  G
Sbjct: 825 KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFG 874



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/302 (24%), Positives = 132/302 (43%), Gaps = 33/302 (10%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P+  K++       + +    P   ++W+K+GQ L  S+ H  I  + HT L+++  Q S
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANGHT-LQIKEAQIS 2738

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR--ETEERIEISEKA 389
            D+G YT        C+ ++  +A E   +  V  Q    +  + Q+  E    ++     
Sbjct: 2739 DTGRYT--------CVASN--IAGEDELDFDVNIQ----VPPSFQKLWEIGNMLDTGRNG 2784

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
             A         +DV         C     P P +TW+ +   +    + K+L+   G   
Sbjct: 2785 EA---------KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS--SDKVLILPGGR-V 2832

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I    + D+G  TCVA N++GE + Q  + V+    ++     +    + V   +  +
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSAL 2891

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +   + G+P PR +WQKDG P++ +   +  ++G    L I   + +D   Y C A+N A
Sbjct: 2892 IECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNG--RILQILNTQITDIGRYVCVAENTA 2949

Query: 570  GS 571
            GS
Sbjct: 2950 GS 2951



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/311 (23%), Positives = 128/311 (41%), Gaps = 40/311 (12%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 3304 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 3348

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               +EK +         D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 3349 ---AEKLMT------LVDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLL- 3392

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 3393 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 3448

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 3449 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 3505

Query: 563  CTAQNVAGSTA 573
            C A N AG  +
Sbjct: 3506 CIASNEAGEVS 3516



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 3625 TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 3682

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 3683 DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 3732

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 3790

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 3791 TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 3895 VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 3950 GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 3984



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 3769

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 3819

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 3880 NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 3923

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 3980

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 3981 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4035

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 4036 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 9/163 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 2030 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSAQISDTGRYTCVAVN 2087

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 2088 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 2142

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P++  P L I  +   S L I  A+  D   Y C A NVAG T
Sbjct: 2143 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKT 2183



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 722  ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 779

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 780  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 829

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 830  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 885

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 886  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 936  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 986

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 987  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPGGE 1044

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 60/204 (29%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 380  EERIEISEKALAPQFVK-----VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            E+ ++   + L P  +K     + ++  V   K    +C  +G P P  +W  + + + +
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
            D +HK L N      L I N  ++D G   CVA N +G       LNV     V+ PK  
Sbjct: 2916 DDHHKFLSN---GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-- 2970

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
                 L V     + L     G P P ++W K+  PI  N    I    G  TL I RAK
Sbjct: 2971 --SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAK 3026

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD   Y C A N AG +  +  L
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSL 3050



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 101/475 (21%), Positives = 177/475 (37%), Gaps = 49/475 (10%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W +   P V   + +++  + +G V  + K +   D G YTC A N  GE  
Sbjct: 1852 GIPNPSITWLKDDQP-VNTAQGNLKI-QSSGRVLQIAKTLLE-DAGRYTCVATNAAGETQ 1908

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              + +                    VS  V+ +           +        +  T  +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
              +  ++   E   + +    + +     G      +TE+  SL     P I+       
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAG------ATELFYSLQVHVAPSISGSNNMVA 2022

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +      + + +  G P P +TW K+G   ++S  + +        L + + Q SD+G Y
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSP-VSSFSNGLQVLSGGRILALTSAQISDTGRY 2081

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T        C+      AV +  E              +QR+ + R+ +    +  +   
Sbjct: 2082 T--------CV------AVNAAGE--------------KQRDIDLRVYVPPNIMGEE--- 2110

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              Q+  V   +     C+    P P +TW  +   +       I  N S    L I +  
Sbjct: 2111 --QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---VLKIEDAQ 2165

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            + D+G  TC A N +G+T     +N+     +      +  + L V EG  + L   + G
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGS---DELTQLTVIEGNLISLLCESSG 2222

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             P P + W+K G P++ +   R+    G   L I  A+ SDAA Y C A NVAG+
Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 3503

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 3560

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 3561 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
            P  V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 1460 PNEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 1510

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 1567

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 1568 ECETRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 1625

Query: 571  S 571
            +
Sbjct: 1626 T 1626



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/281 (24%), Positives = 114/281 (40%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 1851 NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 1901

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 1902 NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1938

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+ ++R +    +   L   +    + I +  +SD+G+  CVA N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQIIDIESAQISDAGIYKCVAIN 1995

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1996 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +  A+ SD   Y C A N AG
Sbjct: 2051 P-VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 2090



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 13/177 (7%)

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            V  D  V    + + +C   G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 1553 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 1609

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
            +SDS   TC   N +G       ++V      V P      +T LN  V     + L  +
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECK 1664

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P+P +TW KDGVP+  N  +RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 12/168 (7%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 4236

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G
Sbjct: 4292 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 4315

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K    + V+E          PP F     +  +    G
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE----------PPVFKGDYPSNWIEPLGG 4365

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 4366 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 4421

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 4422 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 4464

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 4465 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 4520



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 52/187 (27%), Positives = 81/187 (43%), Gaps = 11/187 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+   + +++  T G      C  TG P P++ W +ND  I   + +++    + +  L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM----TSDGTLF 667

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V+ 
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVME 722

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N AG 
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGR 780

Query: 572 TATRARL 578
              +  L
Sbjct: 781 ATGKITL 787



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
            L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 1307 LTGREPGISILEDGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 1363

Query: 398  CQ---DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
             +   +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GKILKLFR 1420

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
             T  D+G  +C A N +G +     ++V+    ++   F    S +  R+   V L  + 
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD---VALECQV 1477

Query: 515  VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 1533

Query: 572  TATRARL 578
             A   +L
Sbjct: 1534 QAKDIKL 1540



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 909

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 966

Query: 570 GS 571
           G+
Sbjct: 967 GT 968



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 4426 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 4480

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 4481 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 4521



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG +    C  +G P P + W      +  D   ++ +  SG   L I+    SD+ +
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL-SGGRQLQISIAEKSDAAL 2266

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             +CVA N +G    +  L V  +  +         + + V  G+ + L     G P P +
Sbjct: 2267 YSCVASNVAGTAKKEYNLQVYIRPTIT--NSGSHPTEIIVTRGKSISLECEVQGIPPPTV 2324

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            TW KDG P+I    + I  +G    L +     SD   Y C A NVAG T
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAVNVAGMT 2372



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 4314

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G   F   +  +  ++   P F   + +  +   G   +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG---FVKAIGFVYVKE--PPVFKGDYPSNWIEPLGGNAIL 4369

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/345 (22%), Positives = 130/345 (37%), Gaps = 37/345 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I +V + D   +  +A +  GT +      V E          PP       NV VT 
Sbjct: 484  LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE----------PPPVIQVPNNVTVTP 533

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L   +      ++ W +N + V+     +I       +L +      D+G+Y C+
Sbjct: 534  GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCM 592

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              +  G +       V                  PP++    K++    G  +   C   
Sbjct: 593  VSSEGGSSAASVFLTVQ----------------EPPKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P P + W   D  I  S  ++M  T+D  TL I  A P+D G Y C+A NSAG     
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRM--TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            + L+  +  +      +    +++V  G     + + +    P ++W +    +   P  
Sbjct: 694  STLRYIEAPK-----LMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPST 746

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +I +    +L I  T + D G +TC A   AG+      L V S
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D  V     T   C     P   +TWF +   +  + N +IL    G   L I N    
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQED 2639

Query: 459  DSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            ++G  +CVA N++GE      + V     I K  +  P    +   + ++    + L   
Sbjct: 2640 NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE 2697

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   P+  ++W KDG P+  +  + I  +G   TL I  A+ SD   Y C A N+AG
Sbjct: 2698 AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAG 2752



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 3762 ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 3876

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 3877 TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 3932 KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 74/294 (25%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            +G+         G P P + W ++GQ L   + H  ++TH    L++   +  DSG YT 
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG-MVLQLLKAETEDSGKYTC 3506

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            +A N  G +     L V  P           +I  +++ E     EIS     P     C
Sbjct: 3507 IASNEAGEVSKHFILKVLEP----------PHINGSEEHE-----EISVIVNNP-LELTC 3550

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                +   KMT       GRP P+        Q++            G   L I+   + 
Sbjct: 3551 IASGIPAPKMTWMK---DGRPLPQTD------QVQ---------TLGGGEVLRISTAQVE 3592

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G  TC+A + +G+   +  + V     +         + L  R+   V L  ++   P
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ---VTLECKSDAVP 3649

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P ITW ++G  +   P +RI +  G   L I  A   D A Y C A N+AG T
Sbjct: 3650 PPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGKT 3701



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L I  V   D+G  TC+
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQIAFVQPGDAGHYTCM 4149

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 4150 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4204

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 4205 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 61/277 (22%), Positives = 112/277 (40%), Gaps = 28/277 (10%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            ++   V    P  + +++NG  +  D   + L+E  +  L I +    D G YEC+A++S
Sbjct: 448  QIPCSVDSLLPFTLSFVRNGVTLGVD---QYLKESASVNLDIAKVTLSDEGFYECIAVSS 504

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG  R      VS                 PP +I+   +  V  G+    +C I+    
Sbjct: 505  AGTGRAQTFFDVS----------------EPPPVIQVPNNVTVTPGERAVLTCLIISAVD 548

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
              + W + D+ ++ ++  ++ RT    +L +      D G+Y C+  +  G    +  L 
Sbjct: 549  YNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            V +P +   +P     ++     G         T   KP I W      I  +  ++M  
Sbjct: 608  VQEPPKVTVMP-----KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            +G    L I N   +D G + C A+ +AG  + ++ L
Sbjct: 663  DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 12/201 (5%)

Query: 402  DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
            +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 955

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 956  GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 1010

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             + W K G  +I     +  + G   +L +      ++  Y CTA N AG    + +L  
Sbjct: 1011 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068

Query: 581  XXXXXXXXXQKRLHLPRPTKV 601
                     Q+ L   +P ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEI 1089



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 12/188 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++V  +  VT G+     C +       +TW  NDR +R        +    N +L 
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVL 510
           + +V  +D+G   C+  ++ G +A    L V E  +V V PK        +   G  V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK------NQSFTGGSEVSI 631

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P+I W  + + I+ +   R+ +DG   TL I  A   DA  Y C A N AG
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688

Query: 571 STATRARL 578
           +    + L
Sbjct: 689 TDKQNSTL 696



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N+ G+++    L   
Sbjct: 2996 LSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   EC    V  P   I WY NG+ +  ST ++ 
Sbjct: 3054 VPPSIKDHDSESLSVVNV---REGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEI 3108

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 3109 LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 104/477 (21%), Positives = 174/477 (36%), Gaps = 55/477 (11%)

Query: 99   PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            P P ++W +   PL   +K  +      G   L I +    D G YTC A N+ GE    
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLIL----PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860

Query: 159  ----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                V + P                 + S  +E  + G+        +  Q +   +   
Sbjct: 2861 YDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--H 2918

Query: 215  HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
            H    + ++       + ++     + +   G +    +  +      V P  I  K  N
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-----VPPSVIGPKSEN 2973

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
              +          ++SG P P ++W KN Q  I  N + +I      TL++   + SD G
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQP-IKLNTNTLIVPGGR-TLQIIRAKVSDGG 3031

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERIEISEKALAPQ 393
             YT +A N  G       L V  P    ++D  S+ ++    RE T   +E    A+ P 
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSLECESNAVPPP 3089

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
             +   ++     G+M      +T   + E+   + D Q+   +  K  V+++G +     
Sbjct: 3090 VITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVSDTGQYVCRAI 3133

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV               +G       LNV     +  P+      T++     PV L   
Sbjct: 3134 NV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS----NPVTLTCD 3174

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C A N+ G
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 4432 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 4482

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 4483 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 4531



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C+  G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 1718

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  I
Sbjct: 1719 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 1776 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 1812



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 1238

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
             TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 1239 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 1296

Query: 521  RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W  +G  +    P + I  DG  + L I      D   Y C A N AG+T  +  L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 14/157 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA----EISVK 3137
            I WF +G  +E++  IR +   G   L+IL  +  ++G YSC ATN+ G+     E+ V 
Sbjct: 2607 ITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVY 2664

Query: 3138 L-ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +   ++K     P  +   + ++ +K   +   EC    +  P   + WY +GQP++   
Sbjct: 2665 IPPIINKGDLWGPGLSP--KEVK-IKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDD 2719

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +   ++ G   L I   Q  D+G Y C A N  GED
Sbjct: 2720 HVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGED 2754



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 62/288 (21%), Positives = 104/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 4132

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 4133 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4192

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 4193 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 4250

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 4251 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 4303

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +   G++ V+ P
Sbjct: 4304 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 3515

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 3516 SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3569

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 3570 PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 3608



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +  S  IR + A G V+  I+  + +D   Y+C A+N+ G    
Sbjct: 3367 TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYTCVASNRAGVDNK 3424

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L+            T  I  ++    G S    C       P M   W  +GQP+  
Sbjct: 3425 HYNLQVFAPPNMDNSMGTEEITVLK----GSSTSMACITDGTPAPSM--AWLRDGQPLGL 3478

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + TVS  G +VL +   +  DSG+Y C A N+ GE
Sbjct: 3479 DAHL-TVSTHG-MVLQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 17/203 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +L+IL T+ TD G Y C A N  G A+   ++ +       G K    T + N       
Sbjct: 2927 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN------- 2979

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                  C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C
Sbjct: 2980 NFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTC 3035

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----E 3280
             A N+ GE   + ++  Y    +     +  S+  +RE  S+    +     P      +
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3095

Query: 3281 PPKFITQIQDVTKLVEGQSAHFE 3303
              + IT+   V  L +GQ  H +
Sbjct: 3096 NGRMITESTHVEILADGQMLHIK 3118



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 64/257 (24%), Positives = 98/257 (38%), Gaps = 22/257 (8%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P + W +K +P++  +   +R    +G   L I      D   Y+C A N  G A 
Sbjct: 2222 GIPPPNLIWKKKGSPVLTDSMGRVRI--LSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279

Query: 157  ----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
                  VYI+P                R  S ++E +  G    T    +    +    G
Sbjct: 2280 KEYNLQVYIRPT-ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG 2338

Query: 213  TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES-DVQISTEIDRSLGPVSPPKIA-- 269
             +            E  +L+  +   S T RYV  + +V   T+    L   +PP I   
Sbjct: 2339 VEILD---------EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389

Query: 270  -QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             + P N  + E        + SG P P +TWFK+G  +  SN   I++      LR+  T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQT 2447

Query: 329  QKSDSGHYTLLAENPNG 345
               D+G YT +  N  G
Sbjct: 2448 TMEDAGQYTCVVRNAAG 2464



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 3728 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 3784

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 3785 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 3883



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           + ES +  L I  VTLSD G   C+A + +G    Q   +V E      P  ++  + + 
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE-----PPPVIQVPNNVT 530

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V  GE  VL    +      +TWQ++   +      RI T    S L++   K +DA  Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEY 589

Query: 562 QCTAQNVAGSTA 573
            C   +  GS+A
Sbjct: 590 HCMVSSEGGSSA 601



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 260  LGPVSPPKIAQKP--RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            L  + PP I  +    + K++E        +++GNP P +TW K+GQ L     H II+ 
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS- 2530

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L++ N Q   +G YT LA +P G
Sbjct: 2531 -GGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 86/218 (39%), Gaps = 35/218 (16%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            ++ IK       E     I  ++L   W KDG+P+++   +    N G+  L IK   + 
Sbjct: 2683 EVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQIS 2738

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEV 1037
            D G YTC A N  G+     ++ I          Q P   +K+  + +     +  E + 
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI----------QVPPSFQKLWEIGNMLDTGRNGEAKD 2788

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD 1097
             I   P                S + E    P   LT    WY +G  +TS++++     
Sbjct: 2789 VIINNP---------------ISLYCETNAAPPPTLT----WYKDGHPLTSSDKVLILP- 2828

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G   L I   + ED+G YT VA N AGE  L   + V
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 74/293 (25%), Positives = 118/293 (40%), Gaps = 46/293 (15%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   + WY +G+ L+      + ++ G  TL + +    D+G YTC A N  GE      
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGEDELDFD 2759

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            V            Q P   + L +I N+ D             TGR  E     KD++ I
Sbjct: 2760 V----------NIQVPPSFQKLWEIGNMLD-------------TGRNGEA----KDVI-I 2791

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +     + E +  P       + W+ +G  + +S ++  +   G  VL+I   K  D+G 
Sbjct: 2792 NNPISLYCETNAAPPP----TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGR 2845

Query: 3121 YSCRATNKWGQ--AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            Y+C A N+ G+   +  V++      KG        +  +      +SA  EC  +    
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLV----NKSALIEC--LSSGS 2899

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P  +  W  +GQP+      K +S+    +L I  TQ  D G YVC A N  G
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAG 2950



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 66/168 (39%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 4012 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4069

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 4070 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 4121

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L IA+ Q  D+G Y C A N  G   T   +  +
Sbjct: 4122 SIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 3236 YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 3287

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 3288 ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 4431

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG P+T+S ++  I   G V L I   + EDAG YT  AVN+ GE      
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVL-ILPGGRV-LQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862

Query: 860  IRVAARSTVT-ADLGIPEQ 877
            +RV     +  A+  +PE+
Sbjct: 2863 VRVLVPPIIKGANSDLPEE 2881



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   N   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 4404

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 4405 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 1311

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 1312 PGISILEDG-TLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            ++   EC++  +  P   V W  +G PL+ K +   I D G++ +    ++  D+G Y+C
Sbjct: 2308 KSISLECEVQGIPPPT--VTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSDTGRYVC 2363

Query: 4049 RATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
             A N+ GM + K  +     P I+ + + P+++  +EK
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 4194 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 4250 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 4300

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V     I        P      P N  
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWI 4360

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 4361 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 4417

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 2104 PNIMGEEQN 2112



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 18/164 (10%)

Query: 3079 SMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            S  + W+ +G+ +++   +  + A G   L+I   + +D+G Y+C A+N  G+ E+   +
Sbjct: 2703 SASLSWYKDGQPLKSDDHVN-IAANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV--PVD-------DPDMKIEWYHNG 3189
                    QK      I N+  L  G++   +  ++  P+         P   + WY +G
Sbjct: 2761 NIQVPPSFQK---LWEIGNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG 2815

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+  S ++  +   G  VL I   +  D+G Y C A N+ GED
Sbjct: 2816 HPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 3255 DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 3312

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            D+G YTC ATN  GE      L V     +     +    EK+  L DTS
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTI---RGNKDEAEKLMTLVDTS 3359



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  +  N     GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 4402

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  N   I  SHR R   + G + ++    K  D+G Y C A+N  G  + 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQ 692

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            +  L  ++  K         +Q+   +  G     EC    +  P +K  W+     +R 
Sbjct: 693  NSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGIPPPQVK--WFKGDLELRP 744

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLE 3250
            ST +  + D    +L I  TQ+ D+G+Y C A N+ G    + T++  G   V+++
Sbjct: 745  STFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD-VGSPPVFIQ 797



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 1170 PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 1268

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 1269 ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 1308

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 1309 GREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 1368 TNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 4078 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 4131

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 15/197 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP    V  ++  ++ G+ A     +I   D ++   W  N + +  +   R +  
Sbjct: 515  DVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLT--WQRNDRDVRLAEPAR-IRT 570

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               + LE+   K  D+G Y C  +++ G +  SV L        Q+P   T +   +   
Sbjct: 571  LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV------QEPPKVTVMPKNQSFT 624

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G      C+      P  KI W  N   +  S R +  SD    + + A     D+G Y
Sbjct: 625  GGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAA---PKDAGIY 679

Query: 3223 VCRAYNKYGEDFTRATI 3239
             C A N  G D   +T+
Sbjct: 680  GCLASNSAGTDKQNSTL 696



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PP    +P   +   G      C  TG+PKP++ W +N   IV   RY++T DG
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 4489 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 4544

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 4545 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGK 875



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 756  LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 809

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 810  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 870  ENQFGKIQSETTVTVTG 886



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 789  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 849  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 1371 SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDA 1426

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST-QNEAG--LEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +   NE    L +   LE + K      + 
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 1486

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 1487 WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C        A+T    G  I+ S +++Y++      
Sbjct: 1546 PSIKGGNVTTDI-SVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 1604

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 1605 IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++ +    + G   L +      D G Y C A +  GE
Sbjct: 1664 KAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV      +L++      D+G YSC+A N  G ++  
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVN--NGKILKLFRATPEDAGRYSCKAINIAGTSQKY 1443

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +           T+  N   +   +    EC V     PD  I W+ +G+P+   
Sbjct: 1444 FNIDVL----VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLG 1497

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 1498 DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +    G  I  E  ++ +  PT  + W+K+G  +   ++   I   G+I L + ++++ D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSD 2357

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
            +G Y C AV+  G+ + K  L V    +I    + PE +  +++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 35/210 (16%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++++  N     E     +  P   + W ++G P+++ + +    + G+  L +K    
Sbjct: 2682 KEVKIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQI 2737

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G YTC A N  GE      + +Q   S Q        L +I  + D+ R    +DV 
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ-------KLWEIGNMLDTGRNGEAKDVI 2790

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +            N P  L         C     P P +   WY +G  L S  +     
Sbjct: 2791 I------------NNPISL--------YCETNAAPPPTL--TWYKDGHPLTSSDKVLILP 2828

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
              G   L I     ED+G YTC A+N  G+
Sbjct: 2829 --GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 57/266 (21%), Positives = 102/266 (38%), Gaps = 11/266 (4%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            L GNP P   W +  A L++    ++R      D SL I+++   D GEYTC A N  G 
Sbjct: 914  LAGNPIPERRWIKNSAMLLQNPYITVR-----SDGSLHIERVQLQDGGEYTCVASNVAGT 968

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               +  +                    +  T+  KA G    +   S++ + ++ ++   
Sbjct: 969  NNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF 1028

Query: 215  HSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
             +  D    V +       E     + T  Y  +  VQ++  +   +          KP 
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYA-KRKVQLTVYVRPRVFGDQRGLSQDKPV 1087

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSD 332
               +  G +     ++   P P +TW K  Q +   S +H  + + +   +++  T+ SD
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSD 1144

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESP 358
            SG Y  +A N  G +  +  L V  P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVP 1170



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 3652 VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 3710 NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 3759

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 3760 YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 3801



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 3952

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 3996



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +G  +  S+ +R +   G  +L ++ T   D+G Y+C   N  G+      L  +
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P        +E +K  +      T     +P  +I W+ +GQP++       +
Sbjct: 2476 ------VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII 2529

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S   F  L I   Q   +G Y C A +  G      ++N +
Sbjct: 2530 SGGRF--LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2568



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  EC+   V      + W+KNG+ +T       + D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHL 3145



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 3299

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+  L 
Sbjct: 3300 NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTLV 3356

Query: 1960 DDS 1962
            D S
Sbjct: 3357 DTS 3359



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 4252 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 4306

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 4307 VN--GHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     S+ +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 4400

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     ED+G YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1385 CQATNQLGEAVTSCALRVIAKKDLILE 1411
            C ATN+ G    S +L + +   + LE
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 4364 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 4419 CVATNEAGVVERSMSLTLQS 4438



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    + KN  F  G          G P P ++WT     +V  ++Y M     T D +
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM-----TSDGT 665

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L IK   P D G Y C A N  G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAG 688



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I +  G     E  ++ I   T  V W+KDG P+  +  +    + G++ L +K++ V 
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI-LQLKNIHVS 2356

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            D G Y C A N  G      +L++     II   + P  +  ++
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G  +L I  V   DAGHYTC A N  G ++TS  LT+
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 1252 TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 1305

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 1306 ELTGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPII 1392



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 3676

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++ N    D+ +YT +A N  G       L V  P
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 3712



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 4429 ERSMSLTLQSPPIITLE 4445



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 20/170 (11%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDI---------IDESVTIKPRFVTRPKSIE 1454
            AK   IL+  H   L+ I ++ DT RY    +          D SV   P  +   +S E
Sbjct: 2336 AKGVEILDEGHILQLKNI-HVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE 2394

Query: 1455 N--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            N  V+E   V   C+   +   +  + WFK+G PV++ +  R +   G   L ++    E
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPS--ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTME 2450

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            D+G YTC   N  G +     L+      IV     E  LE ++V E +S
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLVPPHIV----GENTLEDVKVKEKQS 2496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632  RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 3429 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 3485

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
              G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 3486 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 3518

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 3519 FILKVLEPPHINGSEEHE 3536



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 3605 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 3655

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 3656 LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 3700



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 3766

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 3767 F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 12/174 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C ATN  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 1188

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 1189 DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 1244

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P
Sbjct: 1245 NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKP 1296



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 1579 ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 1635

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +  I+  
Sbjct: 1636 YVPPMIEGNLATPLN--KQVVIAHSLTLECKA--AGNPSPILTWLKDGVPVKANDNIRI- 1690

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 1691 -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG PV  S+ +      G   L +   T+ DAG YTC   NA G+      L+++
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 1003 TKKDIIAES 1011
                I+ E+
Sbjct: 2476 VPPHIVGEN 2484



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 3257 SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++  L D S
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTLVDTS 3359



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 1216

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 1217 HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 1256



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T   ++ S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 1496

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 1497 GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I V  G  +  +C V+ +  PT  + W  +G P      V  L++ G I L +  I+  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GHI-LQLKNIHVSD 2357

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
             G Y C A N  G       ++  A   I+   + P+ +S
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS 2397



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 3261 GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 3319 CVATNPAG 3326



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 4131

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 4132 --SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P+ +    N     G+ V + C     G    ++ W  N   I   HR+R   +
Sbjct: 606  LTVQEPPKVTVMPKNQSFTGGSEVSIMC--SATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI-AKKDLILESQHPSGLEKIQY 1423
                 L + +  P+D+G+Y C A+N  G    +  LR I A K ++++S+    L  I  
Sbjct: 664  G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITV 720

Query: 1424 LE 1425
            +E
Sbjct: 721  ME 722



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 714 ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 769

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 770 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 826

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 881

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 938

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAG 967



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 1351 YNLKVHVPPVIKDKEQ-------VTNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 1400

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 1401 VTESSTIQTVNN--GKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+  IR + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 1725 YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLIDE 1777

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 1778 RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 1813



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEK 2092

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 2093 QRDIDLRV 2100



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 633  VYPPPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V+ PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTN--TLIVP 3015

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            G  +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   V  EC  E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 3071 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 3127 QYVCRAINVAGRD 3139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LEC    +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 4433 SLTLQS 4438



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 860  IRVAARSTVTADLGIPEQRRYI 881
            + V     +  +L  P  ++ +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVV 1654



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ + + +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 2003

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 2004 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 2053

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +   Q  D+G Y C A N  GE
Sbjct: 2054 SFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVNAAGE 2091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G+ +  EC+++ +      V W K+G P+ I  +   I D G++ L + ++   D+G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSDTG 2359

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             Y C AVN+ G  +    L+  +   I+    N    E I V+E  S
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSII---GNHRSPENISVVEKNS 2403



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G++   E ++  +  PT  V W KDG P+  +  +  I + G++ L + ++   D G Y 
Sbjct: 2307 GKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGV-EILDEGHI-LQLKNIHVSDTGRYV 2362

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
              AVN  G       + V A  ++  +   PE    +EK
Sbjct: 2363 CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   EC     P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 3073 EGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 3302 STLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)

Query: 3047 PPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP  +   K+ ++ + +      EA  +P  D    I W  +G+ I  S R R V + G 
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPD----ITWHKDGRAIVESIRQR-VLSSGS 4132

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LK 3162
              L+I   +  D+G Y+C A N  G +  S KL     +    PR    I++ EG   + 
Sbjct: 4133 --LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL-----TVHVPPR----IRSTEGHYTVN 4181

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +   A   C    +  P   I W  +   + +     T   +G ++L+    +  DSG Y
Sbjct: 4182 ENSQAILPCVADGIPTP--AINWKKDNVLLANLLGKYTAEPYGELILENVVLE--DSGFY 4237

Query: 3223 VCRAYNKYGED 3233
             C A N  GED
Sbjct: 4238 TCVANNAAGED 4248



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 788  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 900

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 901  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 956

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 957  EYTCVASNVAG 967



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 1351 YNLKVHVPP 1359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 84/375 (22%), Positives = 143/375 (38%), Gaps = 32/375 (8%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            +NI V E   V   C  E  G P   I WF +G P +  + V  L+  G   L +     
Sbjct: 2394 ENISVVEKNSVSLTC--EASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTM 2449

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+YTC   N  G       ++      IV E+ L      EK        ++  P  
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E       + + + ++H +    G RF  ++   + P      Y      P+GH+ R+  
Sbjct: 2510 EITWHKDGQPLQEDEAHHI--ISGGRF-LQITNVQVP--HTGRYTCLASSPAGHKSRSFS 2564

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVND------FGEDFTKATISCKKLPDIILQNQVPR- 3935
               FVS  I  V ++ + E +   +N           +  ATI+  K    +  N+  R 
Sbjct: 2565 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI 2624

Query: 3936 --GMKRSEALTQMEATIKKYTSEVYLTEDDL---YDVDKKQPP------RFVTQIQSQTS 3984
              G +  + L   E    +Y+        ++   Y+V    PP       +   +  +  
Sbjct: 2625 LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEV 2684

Query: 3985 LVEMETT-KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
             +++  T   EC+   +  P+  + W+ +G+PL   +    I   G+  +        D+
Sbjct: 2685 KIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVN-IAANGH-TLQIKEAQISDT 2740

Query: 4044 GEYLCRATNLYGMDE 4058
            G Y C A+N+ G DE
Sbjct: 2741 GRYTCVASNIAGEDE 2755



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 4429 ERSMSLTLQS 4438



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 87/402 (21%), Positives = 156/402 (38%), Gaps = 41/402 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 791  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 966

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 967  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 1023

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDQRGLS 1082

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 1137

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +    DSG+Y C A N+ G    + +L       I R  ++
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 1544 IPPSIKGGNVTTDI----SVLINSLIKLECETRGLPMP--AITWYKDGQPIMSSSQALYI 1597

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 1598 -DKG-QYLHIPRAQVSDSATYTCHVANVAG 1625



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 2063

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 2064 GGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V  GK+   EC+V+ +  P   + +  +G  L  A    I  D G++ L +++    D G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTG 2359

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             Y   A+N  G       ++V A  SII   + PE +  + +   +   +   IP P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 3261 GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDT--QNEQAIEQIQLLEDAA 1295
              A N  G        R+   +  VT T   N+   E++  L D +
Sbjct: 3319 CVATNPAGEED-----RIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 3359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S      G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 4399

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL+L+S   +   +   +  S        V + V + P+ +T +      + G      C
Sbjct: 575  SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMC 633

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P  ++ W  N   +   HRYR ++D     L I     +D+G Y C A N+ G
Sbjct: 634  SATGYPKP--KIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 1927 QAVSSIRLN-VQSKESIIRDSQHESALEKIQYLE 1959
                +  L  +++ + ++  S+   AL  I  +E
Sbjct: 689  TDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 897  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 952

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 953  QDGGEYTCVASNVAG 967



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 1224

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
             +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 1225 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 1907

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY + + +
Sbjct: 1908 QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNRLL 1961

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1962 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1998



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +   + +D+G Y+C A N  G+ +  + L   
Sbjct: 2043 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVY 2101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 2102 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 2152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S+    VL I   Q  D+G Y C A N  G+      +N +
Sbjct: 2153 SE-NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 54/211 (25%), Positives = 82/211 (38%), Gaps = 34/211 (16%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            S K V+IK       E     +  A+L   WY + +PLKS        N G   L I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASLS--WYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSA 1702
               D+G YTC         V S IA    +    +  Q   +  +L ++ +     R+  
Sbjct: 2736 QISDTGRYTC---------VASNIA-GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
              +VI   P+           E  AA           P   + W ++G P+ +S+++  +
Sbjct: 2786 AKDVIINNPISLY-------CETNAA-----------PPPTLTWYKDGHPLTSSDKVLIL 2827

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G   L +     ED+G YTC A+NE GE
Sbjct: 2828 P--GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633  VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 3052 VYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTH-VEI 3108

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
               G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 3109 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 3154



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 3126

Query: 842  SYTVRAVNKLG 852
             Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             NL +     I          EK+  L D S
Sbjct: 3332 FNLNVYVTPTIRGNKDE---AEKLMTLVDTS 3359



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS+ I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 4403

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 4404 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 4461

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 4462 QATGEPQPTIT 4472



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 18/270 (6%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 1102 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATNIAG 1157

Query: 154  EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
                +V +                        +   A GT       S+    +   +G 
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 1216

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
             H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 1217 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 1269

Query: 272  PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
            P N+  QE    Q   F     G P+P + W  NG+ L    +  I    + T L + + 
Sbjct: 1270 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEDGTLLVIASV 1328

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               D+G Y  +A N  G       L V  P
Sbjct: 1329 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 22/283 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 1225

Query: 131  LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
            L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 188  H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                A GT        + T K  + NG + +  +       +  LL   S        Y+
Sbjct: 1286 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337

Query: 246  GESDVQI-STEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
              +  +  +TE   +L    PP I  K +  N  +          ++ G P P + W+K+
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 1398 NVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ I+     + +     +V  I   + +++G Y C A N  G    
Sbjct: 1759 TGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKK 1816

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 1817 EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 1865

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 1866 PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 724  AVLHVTPRATIE 735
              LHV    ++E
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQIS--DTGRYTCVAVNAAGEKQR 2094

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 2095 DIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P+++I++   S   EC +  +   +  V W  +G PL+    V+ +++ G  IL++  ++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GH-ILQLKNIH 2354

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
              D G Y C A N  G       L V     II   + P +
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            +L++     +D+G Y C A N  G  +    L      S     R   +I  +E  K+  
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE--KNSV 2404

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   E + +P+      I W+ +G P+  S  ++ +S  G  +L +  T   D+G+Y C 
Sbjct: 2405 SLTCEASGIPLPS----ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCV 2458

Query: 3226 AYNKYGED 3233
              N  GE+
Sbjct: 2459 VRNAAGEE 2466



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 34/215 (15%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+    +   EC  E Y  P+  + WY +G+ L+S      + + G   L I      D+
Sbjct: 2685 KIKVNNTLTLEC--EAYAIPSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDT 2740

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G YTC A N  G+      +N+Q   S          L +I  + D  R   A       
Sbjct: 2741 GRYTCVASNIAGEDELDFDVNIQVPPSF-------QKLWEIGNMLDTGRNGEA------- 2786

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
                         +V   +P+ L         PT+   WY +G P+      K     G 
Sbjct: 2787 ------------KDVIINNPISLYCETNAAPPPTL--TWYKDGHPLTSSD--KVLILPGG 2830

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              L I  A  ED G Y C A N  GE      V+V
Sbjct: 2831 RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 3122

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 3123 SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 3170

Query: 3548 LTPEAESGNPP 3558
            LT +A +G PP
Sbjct: 3171 LTCDA-TGIPP 3180



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 785  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 843

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 844  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 1006 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 1063

Query: 724  AVL--HVTPR 731
              L  +V PR
Sbjct: 1064 VQLTVYVRPR 1073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTV-NNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 860  IRVAARSTV 868
            I V    T+
Sbjct: 1446 IDVLVPPTI 1454



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+  +   +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 1510

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1952 ITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 2010 VAPSISGSN 2018



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            +++  + V   P      + PT++  + G+S   EC ++  P P   V W  +G  L   
Sbjct: 2279 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKA 2336

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                  ++     L +  ++  D+G Y C A+N  G       L+V +  SII    H S
Sbjct: 2337 KGVEILDEGHI--LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII--GNHRS 2392

Query: 1951 ALEKIQYLEDDS 1962
              E I  +E +S
Sbjct: 2393 P-ENISVVEKNS 2403



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +C    V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 3124

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 3125 TGQYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 3126

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626  PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 3661

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 3662 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 3529 EGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS 3588
            EG  + IA     +G   T    +E   PP     P+++ ++    A   C +I   D +
Sbjct: 494  EGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550

Query: 3589 MRVEWFHNGKP--LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            +   W  N +   L   +R++T+ +     LE+  V   DAG Y C  ++  G +  S  
Sbjct: 551  LT--WQRNDRDVRLAEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVF 605

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTE 3670
            L V+    + + P+  S F  G+E
Sbjct: 606  LTVQEPPKVTVMPKNQS-FTGGSE 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PPK     K+ +      V   C       PK +I W  N   +   HRYR   D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGY--PKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              +L I     +D+G Y C A N  G D   +T+   + P +++
Sbjct: 664  -GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 916 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 972

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 973 TSVVVHVLP--TIQHGQQILSTIEGI 996



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P+++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 1446 IDVLVPPTIIG-----TNFPNEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 1496

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 1497 GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 1405 KKDLILESQ-HPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            +K +I ++Q   +GL +         +KK    + +V + P   +   S   V++ + V 
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVA 1845

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
             +C    +   N  + W K+ QPV        I   G V L I   + ED+G YTC A N
Sbjct: 1846 LQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902

Query: 1524 LVGTDEVSCRL 1534
              G  +   +L
Sbjct: 1903 AAGETQQHIQL 1913



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S P   + W+KDG P+ ++  I  +   G  +L I++ + ++AG Y+  A N+ GE I  
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658

Query: 858  ASIRV 862
              ++V
Sbjct: 2659 YEVKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+G  L +   ++     G  TL I + + D++G Y+C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2732 IKI 2734
            +K+
Sbjct: 2661 VKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +C    V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 860  IRVAARSTV 868
            + V    T+
Sbjct: 3334 LNVYVTPTI 3342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 3829 GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 3886

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 3887 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 3945

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 3946 ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 3998

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 4056

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQVP 4078



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 4126

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 4127 VLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 791  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 850  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 994  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 1003 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 1058

Query: 154  EA----ICSVYIQP 163
             A      +VY++P
Sbjct: 1059 YAKRKVQLTVYVRP 1072



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/179 (21%), Positives = 72/179 (40%), Gaps = 7/179 (3%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W   G  +      R     G   L+I   + +D+  YSC A+N  G A+    L+    
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY-- 2287

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             +       +H   I  +  G+S   EC V  +  P   + W  +G P+  +  ++ + D
Sbjct: 2288 IRPTITNSGSHPTEII-VTRGKSISLECEVQGIPPP--TVTWMKDGHPLIKAKGVE-ILD 2343

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
             G  +L +      D+G YVC A N  G    +  ++ +    +      P++++ + +
Sbjct: 2344 EGH-ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E  + P  TI WF +G  + +    R     G   L IL    +++G Y C ATN+ GE 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 2194 VNTCTLKV 2201
            +    +KV
Sbjct: 2656 IKHYEVKV 2663



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIH--FETRIE----PVGDPTMKIEWLKNGQSI 679
            P GEEDR++    ++ P       E  K+    +T I       G P  +I WLKNG  +
Sbjct: 3324 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 3383

Query: 680  EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
              SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 3384 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 3421



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 3728 KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 3784 MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 3795

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 3796 IDLQVHVPP 3804



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 4151 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 4204

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 4205 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 1253 EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 1304

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 1305 RELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 1346



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 1259 QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 1312

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 1313 GISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 1354



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 653  KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            K+  ETR    G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC 
Sbjct: 1566 KLECETR----GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCH 1619

Query: 713  AVSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
              +  G AE    + V     IE     P   Q +
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 1654



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284  QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
            + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 1623

Query: 344  NGCIVTSGYLAVESP 358
             G    S ++ V  P
Sbjct: 1624 AGTAEKSFHVDVYVP 1638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+ + +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 2003

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 2004 YSLQVHVAP 2012



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKDG P+     ++   N     L I+   V D G YTC A N  G+   + N+ I
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ WY +G+ + S + +    + G+  L I   +  D+G YT VA N AGE +L   + +
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            +   S       + L+E          +  M       ++K V +   +NP        I
Sbjct: 2763 QVPPSF------QKLWE----------IGNMLDTGRNGEAKDVII---NNP--------I 2795

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C       PT+   W+ +G  +T  S  K     G   L I  A   D G YT  AV
Sbjct: 2796 SLYCETNAAPPPTL--TWYKDGHPLT--SSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851

Query: 1256 NHLGSAHTSAIVRVI 1270
            N  G       VRV+
Sbjct: 2852 NEAGEDSLQYDVRVL 2866



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 3253 PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 3309 ALTSDTGKYTCVATNPAGE 3327



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 3469 WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 3526

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 3527 PHINGSEEH 3535



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 3523 VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 3580

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 3581 GEVLRISTAQVEDTGRYTCLASSPAGD 3607



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 3767

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 4197 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254

Query: 1134 TV 1135
            TV
Sbjct: 4255 TV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 4268 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 4321

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G     G
Sbjct: 4322 DSGTYVCTAENSVGFVKAIG 4341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 4451 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 4506

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 4507 FECVARNLMG 4516



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  KI W  N+  +    RY+ T D +   L I +   +D+GIY C A+NS G+   + +
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 2863 LR 2864
            LR
Sbjct: 696  LR 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 994  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 1106

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 1107 PPPIITWAK 1115



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 265  PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP I     P    +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 1509

Query: 323  LRVRNTQKSDSGHYTLLAENPNG 345
            L ++N +++D G Y     N  G
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 7/149 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            SH   I+   G +I  EC V+    PT  + W  +  PL      +   D  ++ L + +
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKN 2352

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
             +  D+G Y C A N  G       L      +I  + + P+    +  VE+   +   +
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE---NISVVEKNSVSLTCE 2409

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEG 2926
                 +P   + K  W + ++   +++ G
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSG 2438



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   + W+ +G P++     +     G   L IL A  ++ G Y C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2067 VKV 2069
            VKV
Sbjct: 2661 VKV 2663



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 3124

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 3242 QVPPSVAGAEI 3252



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 3439 SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 3494

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 3535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 4100 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSS 4157

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 4158 STSTKLTVHVPPR--IRSTEGH 4177



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 4194 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 4251

Query: 997  ANLTI 1001
             +LT+
Sbjct: 4252 VSLTV 4256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 6/142 (4%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
            Q  + +    L I++    DEG Y+C+A +SAG         V++P     +P      +
Sbjct: 474  QYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVP-----NN 528

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V  G+ A     I S +   + W R    +    +   I    N  L + +    D G
Sbjct: 529  VTVTPGERAVLTCLIISAVDYNLTWQRNDRDV-RLAEPARIRTLANLSLELKSVKFNDAG 587

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C  ++  G    S  L V+
Sbjct: 588  EYHCMVSSEGGSSAASVFLTVQ 609



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK ++ W  N + I  S+R     D     L +K   P+D+G Y C A N  G    +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 1798 STL-FVQSKASLQLESQHESALQKIQQLE 1825
            STL ++++   + ++S+   AL  I  +E
Sbjct: 694  STLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 775  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449

Query: 1003 TKKDII 1008
                II
Sbjct: 1450 VPPTII 1455



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 3833 ITQIKSHTVE----ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            IT   SH  E      + +  EC V+    P   + W ++G  L        + D G + 
Sbjct: 2292 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI- 2347

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGM 3937
            L +  ++  D+G Y+C AVN  G    K  +S    P II  ++ P  +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2396



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            P   + WF +G  L      R     G   L IL   E+N+G Y CVATN+ G
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            DV    P+   C       PT+   W+ +G P  +  +V  L   G   L I      DA
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDA 2843

Query: 3766 GEYTCRATNKWG 3777
            G YTC A N+ G
Sbjct: 2844 GRYTCVAVNEAG 2855



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL TL D+ +
Sbjct: 3334 L------NVYVTPTI-RGNKDEAEKLMTLVDTSI 3360



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 3581

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 3685

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 3686 -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3744

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 3745 TWRKDGAVLAGNHARYSILENGFLHI---QSAH 3774



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L IA V+  D+G YT +A N AG +  S  +TV 
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAI 4187



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP + Q P N  +  G  A     +       +TW +N + +  +    I T  N  +L 
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLE 577

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
           +++ + +D+G Y  +  +  G    S +L V+ P +  V  +   +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSF 623



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 790  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 847  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 897  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 951

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 952  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 1236

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQE 1260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFET-RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            VY PP     L +    +    H  T   +  G+P+  + WLK+G  ++A+         
Sbjct: 1635 VYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR--IEA 1692

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
            G   L+++S    D G+Y C A S  G  E K  + V     IE
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 1736



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 2039 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDID 2097

Query: 860  IRV 862
            +RV
Sbjct: 2098 LRV 2100



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 2099 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 2156

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              + ++     +QD+G YTC A +  G  E
Sbjct: 2157 SVLKIE--DAQVQDTGRYTCEATNVAGKTE 2184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R+  NI  VE  +V L C     G     + WF +G P+   +  R         L L+ 
Sbjct: 2391 RSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQ 2446

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
               ED+G YTC   N  GE      L V+    ++ E+
Sbjct: 2447 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN 2484



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W+KDG P++ S+ +  I + G + L +M    EDAG YT    N  GE
Sbjct: 2414 PLPSITWFKDGWPVSLSNSV-RILSGGRM-LRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P+  + WYKDG+P+ +   +    N G+ +L I   +  D G YT  A N  GE
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGE 2753



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG P+ +S ++      G   L I    V DAG YTC A N  G+ +   ++ ++
Sbjct: 2811 WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+ N++EG     EC    +  P +T  W+ NG+ I          D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPVIT--WYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2177 EDSGTYMCKATNKLG 2191
             D+G Y+C+A N  G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 3147 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
               L +      DSG YTC A +  G A+
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 3449 KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 3504

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3536



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 3769

Query: 325  VRNTQKSDSGHYTLLAENPNG 345
            +++   +D+G Y  +A N  G
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAG 3790



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 4106 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162

Query: 860  IRV 862
            + V
Sbjct: 4163 LTV 4165



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 4419 CVATNEAGVVERS 4431



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 4427 VVERSMSL 4434



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 4433 SLTLQSPPIITLEPVE 4448



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKI 876



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + W KD R +  S+ +T F N G + + I+S  + DAG Y C A N+ G
Sbjct: 1952 ITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +  A  +DTG YT  A
Sbjct: 2029 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVA 2085

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 3261 GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTS 4160

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 4161 TKLTVHVPPRIRSTEGHYTVNENSQAI 4187



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP--FATGSR 3743
            T  D    PP   +++ +N+ V  G      C +    D    + W  N R    A  +R
Sbjct: 512  TFFDVSEPPP--VIQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPAR 567

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            + TL +   ++L++  +   DAGEY C  +++ GS+  +  +T
Sbjct: 568  IRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 700  EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 754

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 755  GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 798



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 1236

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTV 1264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++ +LL SG    T  + G + +DI      
Sbjct: 1929 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNRLL-SGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1985 DAGIYKCVAINSAG 1998



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 1176 KPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +P      S+P    V+ GK+I LEC ++ +  PT  V W  +G  +      +   +  
Sbjct: 2289 RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGH 2346

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
             + L  IH   +DTG Y   AVN  G       + V     I+ + ++ + I  ++
Sbjct: 2347 ILQLKNIHV--SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+ E QS    C +   P P   + W+ +G+ LQ    +   +   F  L I  V    +
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPE--ITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545

Query: 1915 GEYTCKAINNLGQAVSSIRLNV 1936
            G YTC A +  G    S  LNV
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNV 2567



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P D+ +  NS     C       ++  + WF +G PL +   ++ +   G   L+I    
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPAT--ITWFKDGTPLESNRNIRILP--GGRTLQILNAQ 2637

Query: 3624 QRDAGLYTCKATNRHGE 3640
            + +AG Y+C ATN  GE
Sbjct: 2638 EDNAGRYSCVATNEAGE 2654



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 51/193 (26%), Positives = 78/193 (40%), Gaps = 41/193 (21%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            P+  + W+ +G+P  +   V+   + G   L I      D G YTC A+N          
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASN---------- 2749

Query: 3785 ITCSAKRDIVLESQLPQGMSGEKIKE----LERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            I    + D  +  Q+P   S +K+ E    L+ GR  +A  ++ I++ P           
Sbjct: 2750 IAGEDELDFDVNIQVPP--SFQKLWEIGNMLDTGRNGEA--KDVIINNP----------- 2794

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
                  +   C       P L   WY++G  L S  +   +   G V L I     ED+G
Sbjct: 2795 ------ISLYCETNAAPPPTLT--WYKDGHPLTSSDKV-LILPGGRV-LQIPRAKVEDAG 2844

Query: 3901 EYICRAVNDFGED 3913
             Y C AVN+ GED
Sbjct: 2845 RYTCVAVNEAGED 2857



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+I++   S + E    P       + W+ +G PL +  +V  +   G  +L+I      
Sbjct: 2788 DVIINNPISLYCETNAAP----PPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVE 2841

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            DAG YTC A N  GE ++   ++V
Sbjct: 2842 DAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T+  T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 3354 TLVDTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 3409

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3519

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 3520 ILKV-------LEPPHINGSEEHEEI 3538



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 4438 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4494

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 4495 YIADAQ---KEDTSEFECVARNLMGS 4517



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P+     KN   T G  V +  + T    P  ++ W  N   +   HR++ T D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG- 664

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
               L I  A  +D G Y C A+N+ G     S+++
Sbjct: 665  --TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI W  N   +    R+++TSD    TL + +   +D+GIY C A N  G    +ST
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 3001 V 3001
            +
Sbjct: 696  L 696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 756

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 757  -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 794  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 854  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICV 1339

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 1340 AVNEAGTTERKYNLKV 1355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAG 1345



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   P  + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNF---PNEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 1493

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 1471 VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 1527

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 1528 SNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915

Query: 1136 ETRSSID 1142
                S++
Sbjct: 1916 HEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G  + LE  +  +  PT  V W  +G P+ +    +   D G++ L +   +  DTG
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTG 2359

Query: 2049 TYMCKATNAVG 2059
             Y+C A N  G
Sbjct: 2360 RYVCVAVNVAG 2370



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 8/144 (5%)

Query: 3962 DDLYDVDKKQPPRFVTQIQS--QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            D  YD+    PP  +   +S    S+VE  +    C+ +  G P   + WF +G P+   
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLS 2430

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
            N    +   G   +       ED+G+Y C   N  G +     +     P IV ++ L +
Sbjct: 2431 NSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-E 2487

Query: 4080 HMKSIEKIREMEASWQVTPEQVVE 4103
             +K  EK + +  + +VT   V E
Sbjct: 2488 DVKVKEK-QSVTLTCEVTGNPVPE 2510



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + W+ +G  L+S    R     G   L IL    +++G Y+C A N  G+ 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 1929 VSSIRLNV 1936
            +    + V
Sbjct: 2656 IKHYEVKV 2663



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV 3622
            +P ++ +  N++   EC    +  +S+   W+ +G+PL +   V    + G   L+I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 3623 YQRDAGLYTCKATNRHGE 3640
               D G YTC A+N  GE
Sbjct: 2736 QISDTGRYTCVASNIAGE 2753



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDL 1509
            PK ++  +    +  EC+   +  ++L   W+K+GQP+        I   G+  L I + 
Sbjct: 2681 PKEVKIKVNNT-LTLECEAYAIPSASLS--WYKDGQPLKSDDHVN-IAANGHT-LQIKEA 2735

Query: 1510 IAEDSGIYTCRAVNLVGTDEV 1530
               D+G YTC A N+ G DE+
Sbjct: 2736 QISDTGRYTCVASNIAGEDEL 2756



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/120 (30%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            EDS +Y  R  V   +  A    + L     +   +SA  EC     P P  R  W  +G
Sbjct: 2856 EDSLQYDVRVLVPPIIKGAN---SDLPEEVTVLVNKSALIECLSSGSPAP--RNSWQKDG 2910

Query: 1885 K-VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            + +L+  H    SN      L IL     D G Y C A N  G A     LNV    S+I
Sbjct: 2911 QPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2967



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 2986 CEVSGFPPPDL--SWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 3041

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 3042 GESKKKFSLTVYVPPS-IKDHDSES 3065



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 8/151 (5%)

Query: 2194 VNTCTLKVAGHRNI-ILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV---TELR 2249
            +NT TL V G R + I+  +  +G E       Q   ++ +       PP      +E  
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESL 3066

Query: 2250 GTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
               +V EG +   EC+   V  P   I +Y NG+ +  +    I  D G + L I+    
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
             D G+Y  +AIN  G       + V    SI
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 3447 VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 3502

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 3503 KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 3674

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 3675 RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 3722



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 3979

Query: 724  AVLHV 728
              LHV
Sbjct: 3980 VTLHV 3984



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 14/133 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 4217 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 4268

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 4269 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 4322

Query: 3219 SGEYVCRAYNKYG 3231
            SG YVC A N  G
Sbjct: 4323 SGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W +N + +    R+R T D    TL I +    DAG+Y C A N AG
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V    PV  +C+    G+P   I W+ + R   +GS   T  + G I +DI+     
Sbjct: 1929 NETVLVSNPVQLECKA--AGNPVPVITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3764 DAGEYTCRATNKWGS 3778
            DAG Y C A N  G+
Sbjct: 1985 DAGIYKCVAINSAGA 1999



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 3826 VSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNEQ--PIKLNTNTLIVP 3015

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            G  +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN+ GE+   
Sbjct: 2990 GFPPPDLSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 3108 ILADGQMLH 3116



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 2996 LSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 1003 TKKDI 1007
                I
Sbjct: 3054 VPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 724  AVLHVTPRATIERTSQHPETL 744
              L+V    TI       E L
Sbjct: 3332 FNLNVYVTPTIRGNKDEAEKL 3352



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 1791 LGE 1793
             G+
Sbjct: 3605 AGD 3607



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 3712 PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 3768

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 3769 HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 3887

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 3888 TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 3936

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 3937 LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 3985



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 3952

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 3993



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 4260 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 4312

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  +T +   ++   G      C       P +   W  N   I   HRYR T D   
Sbjct: 609  QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDMFIVGSHRYRMTSD--- 663

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
              L I     +D+G Y C A+N  G      TL+
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 1273 TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVT 1329

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 1330 PYDNGEYICVAVNEAGTTERKYNLKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 3510 MKV 3512
            +KV
Sbjct: 1353 LKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAG 1438



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 1671 SKKSI 1675
               S+
Sbjct: 1917 EPPSL 1921



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1946 GNPVPVITWYKDN-RLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L  +T +EG  I      E  G P   + W K G  +   S        G   L +    
Sbjct: 2203 LTQLTVIEGNLISL--LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE 2260

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
              D+  Y+C A +  G A+ +  L V  R TI  +  HP
Sbjct: 2261 KSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHP 2299



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG  + L  +      PNL   W K G  + T +  +     G   L I+     D+ 
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLI--WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2265

Query: 2714 IYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            +Y+C A+N+ G A    ++++  R  +     HP  +
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W+++G P+  +  +  + D G++ L +K ++  D+G Y C A+N  G     
Sbjct: 2318 GIPPPTVTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2375

Query: 1798 STLFVQSKASL 1808
              L V +  S+
Sbjct: 2376 YDLSVHAPPSI 2386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P   + W ++G P+E++  +  +   G   L +     +++G Y+C A NE GE +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 2963 PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GG 3017

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 3430

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 3431 FAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 3791



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 3744 ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3801

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 3802 VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 3852

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 3853 YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 4260 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 4312

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 945  WLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            W ++ R V  +  +RI T  N   ++L +KSV  +DAG Y C   +  G +  S  LT+ 
Sbjct: 553  WQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 1002 -VTKKDIIAESQHPGGLEKIQYLEDASRYSK 1031
               K  ++ ++Q   G  ++  +  A+ Y K
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPK 640



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    PK+ ++   G  V   C          K+ W  N   +   HR+R   D     
Sbjct: 612  PKVTVMPKN-QSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG---T 665

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L I +   +D+GIY C A N  GTD+ +  L
Sbjct: 666  LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            +T+T+   +   + +  + A    Q  + + V   P+  R   +++   G  V + C  Q
Sbjct: 1137 ITETRTSDSGMYLCVATNIAGNVTQAVK-LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G     + W   G  +        +     +++D  +  P D+G+YTC ATN  G   
Sbjct: 1196 --GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT--PSDAGIYTCVATNIAGTDE 1251

Query: 1396 TSCALRV 1402
            T   L V
Sbjct: 1252 TEITLHV 1258



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            +L C +E  G P+  + W+ +   VT  S  +T  + G + L +  AT  D G Y+ +A+
Sbjct: 1379 NLFCEVE--GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAI 1434

Query: 1256 NHLGSAHTSAIVRVIERSDIV-TDTQNEQAI 1285
            N  G++     + V+    I+ T+  NE ++
Sbjct: 1435 NIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 1465



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   + WYKD R ++ S+ +T   N G + ++I   +  DAG Y   A+N  G      
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 859  SIRVAARSTVT 869
            S++V    +++
Sbjct: 2005 SLQVHVAPSIS 2015



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ID  V + P  +   +++ +V+  Q V   C+ + +    L   W K+G P+ +      
Sbjct: 2096 IDLRVYVPPNIMGEEQNV-SVLISQAVELLCQSDAIPPPTLT--WLKDGHPL-LKKPGLS 2151

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            I +   V L I D   +D+G YTC A N+ G  E
Sbjct: 2152 ISENRSV-LKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3694 PPRFTVE-IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP    E   +++ V E   V   C V   G+P   I W  +G+P       H ++   F
Sbjct: 2477 PPHIVGENTLEDVKVKEKQSVTLTCEV--TGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2534

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I  +     G YTC A++  G
Sbjct: 2535 --LQITNVQVPHTGRYTCLASSPAG 2557



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  + E    P+  + W+K+G  L +   +    +    TL I   +  D+G YTC A+N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASN 2749

Query: 2722 LLGE 2725
            + GE
Sbjct: 2750 IAGE 2753



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 2/72 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KDG+P+        F + G + L I +  + D G Y C A N  G A   
Sbjct: 2898 GSPAPRNSWQKDGQPLLEDDH-HKFLSNGRI-LQILNTQITDIGRYVCVAENTAGSAKKY 2955

Query: 997  ANLTIVTKKDII 1008
             NL +     +I
Sbjct: 2956 FNLNVHVPPSVI 2967



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 14/146 (9%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYVALDLLSVY 1376
            N+  V    + L C +   G     + W  N +PIK  T     P        L ++   
Sbjct: 2973 NLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTNTLIVPGGR----TLQIIRAK 3026

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              D G YTC A NQ GE+    +L V       ++      L  +   E TS      + 
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTS----VSLE 3080

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHV 1462
             ES  + P  +T  K+   + E  HV
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHV 3106



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 3073 EGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 3129 VCRAINVAG 3137



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W +N K IE+S  +      G   + I+  +  D G Y C ASN+ G+
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 3318

Query: 146  CTARNQYGE 154
            C A N  GE
Sbjct: 3319 CVATNPAGE 3327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 3357 DTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 3412

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 3413 CVASNRAGVDNKHYNLQV 3430



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 3556 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613

Query: 860  IRV 862
            +RV
Sbjct: 3614 VRV 3616



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 3728 KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 3782

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  +G+ ++   R + ++      L+I  V   DAG YTC A N  G ++ S KL V
Sbjct: 4110 ITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 4364 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 4418

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 4419 CVATNEAG 4426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPP   VP  +VT   G +      I    D    + W +N + +  +     I     +
Sbjct: 519 PPPVIQVP-NNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEP-ARIRTLANL 574

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQ 739
           SL++ S+   D+GEY C   S  G +     L V   P+ T+   +Q
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 702  PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 757

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 758  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 799



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 1007 NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 1063

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 1064 VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 1118

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 1119 LISPFSPRH 1127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 1253

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQE 1277



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +E  P P   + WY +   +      +T N+     L +     ED+G Y+CKAIN  
Sbjct: 1382 CEVEGTPSPI--IMWYKDNVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIA 1437

Query: 1926 GQAVSSIRLNVQSKESII 1943
            G +     ++V    +II
Sbjct: 1438 GTSQKYFNIDVLVPPTII 1455



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1844 PRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            P  I   N P ++S    +    EC+++  P P+  + W+ +GK L  G       D G 
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRG- 1507

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L +      D G Y C   N  G+    I+L +    SI
Sbjct: 1508 QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 1548



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+     +   + G   L+I+ A   
Sbjct: 1650 NKQVVIAHSLTLECKAA--GNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEI 1705

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 1838 VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 1894

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 1895 RYTCVATNAAGE 1906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 1912

Query: 2199 LKV 2201
            L V
Sbjct: 1913 LHV 1915



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 2001 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 2057

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 2058 GLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 2109



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V   +PV LE     +  P++   W  +G PV            G + L +  A   DTG
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLT--WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTG 2079

Query: 2049 TYMCKATNAVGE 2060
             Y C A NA GE
Sbjct: 2080 RYTCVAVNAAGE 2091



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 2034 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVN 2087

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 2088 AAGEKQRDIDLRV 2100



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  + + Q+ + L+  +  +  CQ   +  P +   W  +G PLL K   +   +   +
Sbjct: 2103 PPNIMGEEQNVSVLIS-QAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENRSVL 2159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V  +D+G Y C ATN+ G  E    +     P I
Sbjct: 2160 KIEDAQV--QDTGRYTCEATNVAGKTEKNYNVNIWVPPNI 2197



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G ++ LEC +Q +   T  V W  +G P+          E     L L +++  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSD 2357

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            +G Y C A N  G       L V A   +I   + P  +  ++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P   + W ++G P+  SN +  +   G   L +     ED+G YTC   N  GE
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P ++ +  N SA  EC  +     + R  W  +G+PLL     K +++    IL+I    
Sbjct: 2879 PEEVTVLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQ 2934

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQV 3649
              D G Y C A N  G A     L V
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNV 2960



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/71 (33%), Positives = 31/71 (43%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N   IE S+ L      G   L +      DSG YTC A N  G+A   
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 1798 STLFVQSKASL 1808
              L +Q   S+
Sbjct: 3237 YFLSIQVPPSV 3247



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 4165 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 4222

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 4223 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 4426


>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-153O3 on chromosome 1. ).
          Length = 5635

 Score =  129 bits (312), Expect = 2e-28
 Identities = 107/384 (27%), Positives = 161/384 (41%), Gaps = 35/384 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  ++ A  E    G P P   W ++  P+      +    S   IL I    + D   +
Sbjct: 2884 VLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRILQILNTQITDIGRY 2941

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGT 4540
              VAEN  G+AK   NL V           VPPS     ++N+ V     + L  +V+G 
Sbjct: 2942 VCVAENTAGSAKKYFNLNVH----------VPPSVIGPKSENLTVVVNNFISLTCEVSGF 2991

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P D+ WLKN + ++ +    I+   G  TL I+ A   D G+Y C+AIN AGE++    
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V +P       P  K  ++     E L    V EG ++   C+    P P + WYK  
Sbjct: 3050 LTVYVP-------PSIKDHDS-----ESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3097

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            ++I  S + ++   AD   L I +A   D G Y C A N AGR      L V  P   + 
Sbjct: 3098 RMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155

Query: 4721 LPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                 P R+++V     P       T    PTI WL+    I  +   ++      + L 
Sbjct: 3156 -----PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVE 4803
            I  +   D+G +TC A+   G+ +
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQ 3234



 Score =  119 bits (287), Expect = 2e-25
 Identities = 103/380 (27%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 1148

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 1149 LCVATNIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 1257 HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 1305

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   D   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 1306 EL--TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               +T   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 1364 KEQVT---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKL 1418

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 1419 FRATPEDAGRYSCKAINIAG 1438



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/371 (27%), Positives = 155/371 (41%), Gaps = 39/371 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + W R +  ++ +   +I T +  S L ++ V   D+  +  +  + GG++  S  L V+
Sbjct: 551  LTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E          PP  T+  +N + T G  V +    TG     + W  N   +    R +
Sbjct: 610  E----------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYR 659

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             +  DGT  L I  A P+D+G Y C+A NSAG                DK     +   A
Sbjct: 660  -MTSDGT--LFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEA 701

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P +++    + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+
Sbjct: 702  P-KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLK 758

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I E    D GDY CVA N AGR T    L V  P      PA     D+ +  G      
Sbjct: 759  IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLP 813

Query: 4742 TQITSKIKPTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              +    +PTI+W R +   I   P     I +     L I N +  D GT+ C A    
Sbjct: 814  CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 4800 GQVETSAKLVV 4810
            G++++   + V
Sbjct: 874  GKIQSETTVTV 884



 Score =  115 bits (276), Expect = 5e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 4237

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 4238 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 4287

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 4288 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 4344 YVKEP-------PVFKG-DYPSNWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 4388

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 4389 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 4441

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 4442 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 4497

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 4498 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score =  113 bits (271), Expect = 2e-23
 Identities = 103/405 (25%), Positives = 158/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 1227

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 1282

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + EDGT  L+I    P D+G+Y CVA+
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAV 1341

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDK---------------EQVTNVSVLLNQLTNLFCEVEG 1386

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 1387 TPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P      ++ V   +    + Q+     P I W ++G  L    P
Sbjct: 1445 NIDVLVPPTIIGTNFP-----NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 1500 NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  110 bits (264), Expect = 1e-22
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI-VPGGRTLQI 3022

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N+ G +K   +L V           VPPS     + +   VNV
Sbjct: 3023 IR-AKVSDGGEYTCIAINQAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 3071

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 3129

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 3174

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 3235 KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  109 bits (261), Expect = 3e-22
 Identities = 100/368 (27%), Positives = 151/368 (41%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 3271 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 3330

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         TL   ++N+        + + TGT P  + WLKNG  
Sbjct: 3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI--------ECRATGTPPPQINWLKNGLP 3382

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 3383 LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 3438

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 3439 ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 3486

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 3487 HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 3541

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 3542 VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 3598

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 3599 CLASSPAG 3606



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 3054 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI--LAD 3111

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 3112 GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 3161

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 3267

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 3268 CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L  +V         + + T    P I WL+ G  +P
Sbjct: 3328 EDRIFNLNVYVTPTIRGNKDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLP 3384

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 3385 LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 3420



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/407 (25%), Positives = 164/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 4043

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 4093

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMA 4150

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 4151 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 4194

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 4195 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 4250 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 4301

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+    + VK
Sbjct: 4302 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346



 Score =  106 bits (255), Expect = 2e-21
 Identities = 91/382 (23%), Positives = 165/382 (43%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P++ W ++  P+K + + +I     K  ++  Q    D   +  VA +  G
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAG 1719

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWL 4548
              +    + V          +VPP+     +     V    L+ LD  VTG+ P  + WL
Sbjct: 1720 EKEIKYEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWL 1769

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P  
Sbjct: 1770 KDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP-- 1825

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  K++         L +++V + + +   C   G P P++ W K D+ +  ++ 
Sbjct: 1826 -----PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ- 1871

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              +   +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L 
Sbjct: 1872 GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LN 1929

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            + V+    P Q + +      P I W ++  L+  +     ++ G   ++ I +    D 
Sbjct: 1930 ETVLV-SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDA 1986

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A  +AG  E    L V
Sbjct: 1987 GIYKCVAINSAGATELFYSLQV 2008



 Score =  105 bits (253), Expect = 3e-21
 Identities = 122/485 (25%), Positives = 195/485 (40%), Gaps = 59/485 (12%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            ++ G P P +SW + + P+    K +       G  +L I +    D GEYTC A NQ G
Sbjct: 2987 EVSGFPPPDLSWLKNEQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 154  EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
            E+      +VY+ P                   S ++E ++                  Y
Sbjct: 3043 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITW--------Y 3094

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
             NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 3095 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 3152

Query: 268  IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
            I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 3153 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIA 3212

Query: 327  NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 3213 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 3253

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                         D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 3254 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREG 505
            +  L I     SD+G  TCVA N +GE      LNV     +   K   E+  TL     
Sbjct: 3302 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTL---VD 3357

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              + +  RA GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A
Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVA 3415

Query: 566  QNVAG 570
             N AG
Sbjct: 3416 SNRAG 3420



 Score =  105 bits (252), Expect = 4e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 3420

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 3421 VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 3471 RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 3526

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 3527 -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 3573

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 3574 -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 3629

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 3687

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 3688 ANYTCVASNIAGKTTREFILTV 3709



 Score =  105 bits (251), Expect = 5e-21
 Identities = 101/395 (25%), Positives = 161/395 (40%), Gaps = 35/395 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP    + Q   V   +      + D  P P + W ++  P+   P   I     +S+L 
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTS 4527
            I    V+D+  +   A N  G  + + N+ +           VPP+   + +   + V  
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW----------VPPNIGGSDELTQLTVIE 2210

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G L+ L  + +G  P ++ W K G  V  D   ++    G   L I  A   D+  Y CV
Sbjct: 2211 GNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCV 2270

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG A+ +    V +  T       T + + P EI       IV  G++I   C++ 
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPT------ITNSGSHPTEI-------IVTRGKSISLECEVQ 2317

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PTV W K G  LIK +K  ++    + + L++      D G Y CVA N AG    
Sbjct: 2318 GIPPPTVTWMKDGHPLIK-AKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2374

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V  P     +       +I V E        + +    P+I W ++G  +  +  
Sbjct: 2375 KYDLSVHAPPSI--IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNS 2432

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +++  G   +L +  T  ED G +TC    AAG+
Sbjct: 2433 VRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score =  104 bits (250), Expect = 7e-21
 Identities = 109/409 (26%), Positives = 167/409 (40%), Gaps = 41/409 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 850

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 851  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 902

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 903  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 959

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 960  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 1003

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSS-AKFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYAK 1061

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +   L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V
Sbjct: 1122 PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score =  104 bits (250), Expect = 7e-21
 Identities = 96/377 (25%), Positives = 155/377 (41%), Gaps = 34/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P  +W + +  +  +P   + +  +   L I +V ++D   +  VA N  GT   +
Sbjct: 916  GNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT 972

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             ++VV           V P+     Q ++   G  V L  K +G     V W K G+ + 
Sbjct: 973  TSVVVH----------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                      DG+  L ++    ++SG+Y C A N+AG A+   +  V +       +P+
Sbjct: 1023 TSSAKFSAGADGS--LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYV-------RPR 1073

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT- 4674
                       +P++  ++A G+ +   C++   P P + W K  +LI P   F    T 
Sbjct: 1074 VFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITWAKETQLISP---FSPRHTF 1129

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +++I+E    D G Y CVA N AG VT A KL V  P +    P     + + V  
Sbjct: 1130 LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQV 1184

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            GQ             P I W + G+ +    D +      +  L I      D G +TC 
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCV 1242

Query: 4795 ATTAAGQVETSAKLVVK 4811
            AT  AG  ET   L V+
Sbjct: 1243 ATNIAGTDETEITLHVQ 1259



 Score =  104 bits (250), Expect = 7e-21
 Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKE 1817

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 1818 FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 1868 NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 1919

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK ++L+  S    M+  
Sbjct: 1920 SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFL 1970

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1971 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 2025

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +    DTG +TC 
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSAQISDTGRYTCV 2084

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 2085 AVNAAGEKQRDIDLRV 2100



 Score =  104 bits (250), Expect = 7e-21
 Identities = 102/369 (27%), Positives = 147/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W + +  I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 3237 YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 3286

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 3287 IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 3339

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +  L D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 3340 PTIRGNKDEAEKLMTLVDT------SINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 3391

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 3392 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 3448

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3506

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 3507 IASNEAGEV 3515



 Score =  104 bits (249), Expect = 9e-21
 Identities = 101/398 (25%), Positives = 164/398 (41%), Gaps = 40/398 (10%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVF 4474
            KM    V      + E +  G P+P+I WY++N  +  S      TF  +  +I I    
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSM---TFLNRGQIIDIESAQ 1982

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + D+ ++  VA N  G  +   +L V           V PS + +   V V     VRL+
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH----------VAPSISGSNNMVAVVVNNPVRLE 2032

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +  G     + WLK+G  V     N +    G   L +  A   D+G+Y CVA+N+AGE
Sbjct: 2033 CEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             + D +  V +                PP I+   ++  V   QA+E  C+    P PT+
Sbjct: 2092 KQRDIDLRVYV----------------PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135

Query: 4655 QWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             W K G  L+K      +S + +   L+I +A  +D G Y C A N AG+      + + 
Sbjct: 2136 TWLKDGHPLLKKP---GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHE 4772
             P    N+     L  + V EG       + +    P + W ++G+ ++ ++     I  
Sbjct: 2193 VP---PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS 2249

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G    L I    + D   ++C A+  AG  +    L V
Sbjct: 2250 GGRQ-LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286



 Score =  102 bits (245), Expect = 3e-20
 Identities = 96/389 (24%), Positives = 155/389 (39%), Gaps = 31/389 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  +   R E E  G P P + W ++  P+ +  +  +   S   IL +    + D+  +
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRY 2081

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G  +   +L V           VPP+     QNV+V   Q V L  +     
Sbjct: 2082 TCVAVNAAGEKQRDIDLRV----------YVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  + WLK+G  +       I E      L I +A  QD+G+Y C A N AG+   +   
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNVAGKTEKNYNV 2189

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             + +P       P    +       + L    V EG  I   C+  G P P + W K   
Sbjct: 2190 NIWVP-------PNIGGS-------DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +      ++   +    L+IS A   D   Y CVA N AG       L+V       N 
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
             +     +I+V  G+    + ++     PT+ W+++G  + +    +++ EG+  +L + 
Sbjct: 2296 GSHPT--EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQLK 2351

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            N +  DTG + C A   AG  +    L V
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380



 Score =  101 bits (243), Expect = 5e-20
 Identities = 101/380 (26%), Positives = 148/380 (38%), Gaps = 35/380 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 1006 GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPGG-EESGEYVCTATNTAGYAKRK 1063

Query: 4496 ANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V  + R    + G+           ++V +G+ V L  +V    P  + W K  + 
Sbjct: 1064 VQLTVYVRPRVFGDQRGLSQDK----PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 1119

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P          G+  + I E    DSG Y CVA N AG      +  V          
Sbjct: 1120 ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV---------- 1167

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S 
Sbjct: 1168 ------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIV 4731
               + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V
Sbjct: 1222 P--DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 1279

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                Q  +F        KPTI+WL  G  L    P   ++ +G   +L+I +    D G 
Sbjct: 1280 A--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGE 1335

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A   AG  E    L V
Sbjct: 1336 YICVAVNEAGTTERKYNLKV 1355



 Score =  101 bits (241), Expect = 8e-20
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 3912

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 3970

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 3971 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 4013

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 4014 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 4071

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 4072 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 4126 RVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 1242 VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 1293

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 1294 PKPTIKWLHNGRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 1353 LKVH----------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 1400

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 1453

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 1506

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 1507 GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 1561

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 1562 NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 1619

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 1620 VANVAGTAEKS 1630



 Score =  100 bits (239), Expect = 1e-19
 Identities = 106/423 (25%), Positives = 169/423 (39%), Gaps = 31/423 (7%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKK-MQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T +   A  +ER + G      P I  +  ++  +V E +      E  G P+P I W++
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK 2515

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRR 4505
            +  P++   D   H  S    L I  V V  +  +  +A +  G    S +L V      
Sbjct: 2516 DGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
             G G    P      ++V V       L  +     P  + W K+G  ++ +   +IL  
Sbjct: 2574 AGVGSDGNP------EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL-- 2625

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             G  TL IL A   ++G+Y CVA N AGE     E  V +P   +K         +P E+
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL-SPKEV 2684

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
                K K+      +   C+    P  ++ WYK  + +K   +  ++  A+ +TL+I EA
Sbjct: 2685 ----KIKV---NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA--ANGHTLQIKEA 2735

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-------VVYEGQPA 4738
               D G Y CVA N AG   +   + +  P     L  +  + D         V    P 
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +  +   PT+ W ++G   P T   +++      VL I     ED G +TC A   
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNE 2853

Query: 4799 AGQ 4801
            AG+
Sbjct: 2854 AGE 2856



 Score =   99 bits (238), Expect = 2e-19
 Identities = 82/299 (27%), Positives = 123/299 (41%), Gaps = 40/299 (13%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P    +  G     + ++ G P P VTW K+G  LI +   EI+    H  L+++N   S
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGH-ILQLKNIHVS 2356

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            D+G Y  +A N  G       L+V +P  S + + RS                       
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHRS----------------------- 2392

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ + V +   V+        C  +G P P +TWF +   +    + +IL   SG   L 
Sbjct: 2393 PENISVVEKNSVS------LTCEASGIPLPSITWFKDGWPVSLSNSVRIL---SGGRMLR 2443

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +   T+ D+G  TCV RN +GE      L+V+    +V    +E    + V+E + V L 
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE---DVKVKEKQSVTLT 2500

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG P+    +   H   G   L I   +      Y C A + AG
Sbjct: 2501 CEVTGNPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 35/375 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E E  G P P + W ++  P+  +   +I       IL ++ + V D+  +  VA N  G
Sbjct: 2313 ECEVQGIPPPTVTWMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT---LTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
                  +L V            PPS      + +N++V     V L  + +G     + W
Sbjct: 2371 MTDKKYDLSVH----------APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITW 2420

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G  V   + N +    G   L +++   +D+G+Y CV  N+AGE R      V +P 
Sbjct: 2421 FKDGWPVS--LSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP- 2477

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                  P     N        L+D  V E Q++  +C++ G P+P + W+K  + ++  +
Sbjct: 2478 ------PHIVGENT-------LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               +   +    L+I+       G Y C+A + AG  + +  L V        + +    
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
             D+ V    P     +  S    TI W ++G  +    + +++  G    +L  N  E++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL--NAQEDN 2640

Query: 4788 TGTFTCRATTAAGQV 4802
             G ++C AT  AG++
Sbjct: 2641 AGRYSCVATNEAGEM 2655



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 95/380 (25%), Positives = 157/380 (41%), Gaps = 34/380 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E +  P P + WY++  P+ +S    I       +L I +  VED+  +  VA N  G  
Sbjct: 2800 ETNAAPPPTLTWYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857

Query: 4493 KCSANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                ++ V+     +G    +P       + V V   +   ++   +G+      W K+G
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLP-------EEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2910

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            + +  D  +K L       L IL     D G+Y CVA N+AG A+               
Sbjct: 2911 QPLLEDDHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAK--------------- 2953

Query: 4612 PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             K      + PP +I P  + + V     I  +C++ G P P + W K ++ IK +    
Sbjct: 2954 -KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +       TL+I  A   D G+Y C+A N AG       L V  P    +  + + L  +
Sbjct: 3013 I--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-LSVV 3069

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG     + +  +   P I W + G +I E+   +++ +G   +L I      DTG 
Sbjct: 3070 NVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQ 3127

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + CRA   AG+ + +  L V
Sbjct: 3128 YVCRAINVAGRDDKNFHLNV 3147



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 88/301 (29%), Positives = 127/301 (42%), Gaps = 37/301 (12%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 1051

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 1052 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 1090

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 1091 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 1143

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 579  Y 579
            +
Sbjct: 1257 H 1257



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF 4137

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 4138 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 4184

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 4185 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 4241

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 4242 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 4286 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKAIG 4341

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 4394

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 4395 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 88/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 1227

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 1268

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 1269 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 1318

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
             G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ + ++V  
Sbjct: 1319 DGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVTNVSVLL 1374

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 1375 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCK 1432

Query: 565  AQNVAGST 572
            A N+AG++
Sbjct: 1433 AINIAGTS 1440



 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 96/388 (24%), Positives = 160/388 (41%), Gaps = 36/388 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E        E  G PLP I W+++ +P+  S   +I   S   +L + Q  +ED+  +
Sbjct: 2398 VVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRMLRLMQTTMEDAGQY 2455

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTG 4539
              V  N  G          EE++  G   +VPP      T ++V V   Q V L  +VTG
Sbjct: 2456 TCVVRNAAG----------EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                ++ W K+G+ +Q D  + I+   G   L I       +G+Y C+A + AG      
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
               V +      P      ++  PE      D  V         C+    P  T+ W+K 
Sbjct: 2564 SLNVFV-----SPTIAGVGSDGNPE------DVTVILNSPTSLVCEAYSYPPATITWFKD 2612

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP---D 4716
               ++ ++  ++       TL+I  A  ++ G Y CVA N AG +    ++KV  P   +
Sbjct: 2613 GTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2670

Query: 4717 QADNL-PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
            + D   P L+P +++ +        + +  +    ++ W ++G   P   D  +    N 
Sbjct: 2671 KGDLWGPGLSP-KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ--PLKSDDHVNIAANG 2727

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              L I      DTG +TC A+  AG+ E
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDE 2755



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 64/209 (30%), Positives = 88/209 (42%), Gaps = 8/209 (3%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYP 421
            +   QY    +    EER       L P  +      +D  V E +     C VTG P P
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            E+TW  + + +++D  H I+   SG   L ITNV +  +G  TC+A + +G  +    LN
Sbjct: 2510 EITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V     +           + V    P  L   A   P   ITW KDG P+  N  +RI  
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2626

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G  TL I  A+  +A  Y C A N AG
Sbjct: 2627 --GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 3896

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 3951

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 4006

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 4007 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 4065 GTALGKIKL 4073



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 99/397 (24%), Positives = 159/397 (40%), Gaps = 41/397 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N  V  
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1934

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+ + +        L       + I  A   D+G Y+CV
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1992

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1993 AINSAGA----TELFYSL------------QVHVAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++ A   D G Y CVA N+AG    
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 2095 DIDLRVYVPPN-----IMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              +    N +VL I +   +DTG +TC AT  AG+ E
Sbjct: 2150 LSI--SENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 96/379 (25%), Positives = 156/379 (41%), Gaps = 42/379 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W   +  I  S  +++ +  T   L I+    +D+ ++  +A N  GT K +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            + L   E           P   +    + V  G +  ++ K +G  P  V W K   +++
Sbjct: 694  STLRYIEA----------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P   +  L  D    LL I E    D+G Y CVAIN AG A                   
Sbjct: 744  P---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI--------------- 785

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             T    +PP  I+   D  +  G  +   C + G P PT++W + D +   S+ F +S  
Sbjct: 786  -TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 4675 ADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +   T  L I   +  D+G Y C A N  G+  + ++  VT       L  ++P    V+
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK--IQSETTVTVTGLVAPLIGISPSVANVI 902

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQ      T +     P  +W++  A++ + P   +  +G+   L I     +D G +
Sbjct: 903  -EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEY 958

Query: 4792 TCRATTAAGQVETSAKLVV 4810
            TC A+  AG    +  +VV
Sbjct: 959  TCVASNVAGTNNKTTSVVV 977



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 86/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ +  G     + W 
Sbjct: 1533 KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY 1582

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 1583 KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 1638

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   CK  G P P + W K    +K +  
Sbjct: 1639 -----PMIEG-----NLATPLNKQVVI-AHSLTLECKAAGNPSPILTWLKDGVPVKANDN 1687

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             ++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 1688 IRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 1742

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G LI E   F+++  G    L+I      +T
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNT 1800

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTV 1822



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V+G P P+++W  N++ I+ + N  I+    G   L I    +SD G  TC+A N++G
Sbjct: 2986 CEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 3043 ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3101

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 3102 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 3137



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 87/367 (23%), Positives = 146/367 (39%), Gaps = 17/367 (4%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W+++  P++++ + +I        L I     +++  ++ VA N  G       
Sbjct: 2603 PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V       +G +  P   L+ + V +     + L+ +        + W K+G+ ++ D
Sbjct: 2661 VKVYIPPIINKGDLWGPG--LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2718

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                I      +TL I EA   D+G+Y CVA N AGE   D +  + +P +  K      
Sbjct: 2719 DHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
              +         KD I+     I   C+    P PT+ WYK G  L    K   +     
Sbjct: 2777 MLDTGRN--GEAKDVII--NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PG 2829

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L+I  A  ED G Y CVA N AG  ++   ++V  P       +  P  ++ V   +
Sbjct: 2830 GRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP-EEVTVLVNK 2888

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  +   +    P   W ++G  + E    + +   N  +L I NT   D G + C A 
Sbjct: 2889 SALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRILQILNTQITDIGRYVCVAE 2946

Query: 4797 TAAGQVE 4803
              AG  +
Sbjct: 2947 NTAGSAK 2953



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 3607

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 3608 -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 3661

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 3662 LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 3712

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 3713 PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 3762

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 3763 LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 3815

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 3816 IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 3875

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 3876 CTVTNGAGDDKRTVDLTVQ 3894



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 3553 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 3602

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 3603 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 3640

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
              +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 3641 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 3696

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 3697 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 3752 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 4064

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 4065 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 4119

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 4120 VESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 1835 ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 1892

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 1893 AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1947

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1948 PVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 2000



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 13/217 (5%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
            R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  + + I +    KIL+N      L+I    +S++G+  C+A N +G+   +  + V 
Sbjct: 1767 MWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTD 542
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I + 
Sbjct: 1824 VPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSS 1879

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 1880 G--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 49/290 (16%)

Query: 293  PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGY 352
            P   +TWFK+G  L ++    I+      TL++ N Q+ ++G Y+ +A N  G ++    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            + V  P                       + ++    L+P+ VK+  +  +T       +
Sbjct: 2661 VKVYIPP-------------------IINKGDLWGPGLSPKEVKIKVNNTLT------LE 2695

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C     P   ++W+ + + ++ D +  I  N    H L I    +SD+G  TCVA N +G
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAG 2752

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNV----REGE--------PVVLNARAVGTPTP 520
            E      +N+      V P F + +   N+    R GE        P+ L       P P
Sbjct: 2753 EDELDFDVNI-----QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2807

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +TW KDG P+  + ++ I    G   L IPRAK  DA  Y C A N AG
Sbjct: 2808 TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAG 2855



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 52/350 (14%)

Query: 229 RLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGAD 282
           R L  +S   +S+     GE    +S+E   S   V      PPK+   P+N     G++
Sbjct: 569 RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSE 628

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
                  +G P+P++ W  N   ++ S+++ + +     TL ++N    D+G Y      
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY------ 679

Query: 343 PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
             GC+ ++      + T+              +Q  T   IE      AP+ + V  +  
Sbjct: 680 --GCLASNS-----AGTD--------------KQNSTLRYIE------APKLMVVQSELL 712

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L I      D+G 
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGD 769

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TCVA N++G    +  L+V        P F++  + +++  G  V L     G P P I
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI 824

Query: 523 TWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            W++ D +PI   P  +   +      L I    ASD   Y C A+N  G
Sbjct: 825 KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFG 874



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/302 (24%), Positives = 132/302 (43%), Gaps = 33/302 (10%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P+  K++       + +    P   ++W+K+GQ L  S+ H  I  + HT L+++  Q S
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANGHT-LQIKEAQIS 2738

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR--ETEERIEISEKA 389
            D+G YT        C+ ++  +A E   +  V  Q    +  + Q+  E    ++     
Sbjct: 2739 DTGRYT--------CVASN--IAGEDELDFDVNIQ----VPPSFQKLWEIGNMLDTGRNG 2784

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
             A         +DV         C     P P +TW+ +   +    + K+L+   G   
Sbjct: 2785 EA---------KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS--SDKVLILPGGR-V 2832

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I    + D+G  TCVA N++GE + Q  + V+    ++     +    + V   +  +
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSAL 2891

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +   + G+P PR +WQKDG P++ +   +  ++G    L I   + +D   Y C A+N A
Sbjct: 2892 IECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNG--RILQILNTQITDIGRYVCVAENTA 2949

Query: 570  GS 571
            GS
Sbjct: 2950 GS 2951



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/311 (23%), Positives = 128/311 (41%), Gaps = 40/311 (12%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 3304 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 3348

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               +EK +         D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 3349 ---AEKLMT------LVDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLL- 3392

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 3393 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 3448

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 3449 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 3505

Query: 563  CTAQNVAGSTA 573
            C A N AG  +
Sbjct: 3506 CIASNEAGEVS 3516



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 3625 TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 3682

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 3683 DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 3732

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 3790

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 3791 TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 3895 VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 3950 GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 3984



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 3769

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 3819

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 3880 NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 3923

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 3980

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 3981 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4035

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 4036 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 9/163 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 2030 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSAQISDTGRYTCVAVN 2087

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 2088 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 2142

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P++  P L I  +   S L I  A+  D   Y C A NVAG T
Sbjct: 2143 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKT 2183



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 722  ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 779

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 780  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 829

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 830  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 885

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 886  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 936  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 986

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 987  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPGGE 1044

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 60/204 (29%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 380  EERIEISEKALAPQFVK-----VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            E+ ++   + L P  +K     + ++  V   K    +C  +G P P  +W  + + + +
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
            D +HK L N      L I N  ++D G   CVA N +G       LNV     V+ PK  
Sbjct: 2916 DDHHKFLSN---GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-- 2970

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
                 L V     + L     G P P ++W K+  PI  N    I    G  TL I RAK
Sbjct: 2971 --SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAK 3026

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD   Y C A N AG +  +  L
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSL 3050



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 101/475 (21%), Positives = 177/475 (37%), Gaps = 49/475 (10%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W +   P V   + +++  + +G V  + K +   D G YTC A N  GE  
Sbjct: 1852 GIPNPSITWLKDDQP-VNTAQGNLKI-QSSGRVLQIAKTLLE-DAGRYTCVATNAAGETQ 1908

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              + +                    VS  V+ +           +        +  T  +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
              +  ++   E   + +    + +     G      +TE+  SL     P I+       
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAG------ATELFYSLQVHVAPSISGSNNMVA 2022

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +      + + +  G P P +TW K+G   ++S  + +        L + + Q SD+G Y
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSP-VSSFSNGLQVLSGGRILALTSAQISDTGRY 2081

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T        C+      AV +  E              +QR+ + R+ +    +  +   
Sbjct: 2082 T--------CV------AVNAAGE--------------KQRDIDLRVYVPPNIMGEE--- 2110

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              Q+  V   +     C+    P P +TW  +   +       I  N S    L I +  
Sbjct: 2111 --QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---VLKIEDAQ 2165

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            + D+G  TC A N +G+T     +N+     +      +  + L V EG  + L   + G
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGS---DELTQLTVIEGNLISLLCESSG 2222

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             P P + W+K G P++ +   R+    G   L I  A+ SDAA Y C A NVAG+
Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 3503

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 3560

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 3561 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
            P  V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 1460 PNEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 1510

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 1567

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 1568 ECETRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 1625

Query: 571  S 571
            +
Sbjct: 1626 T 1626



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/281 (24%), Positives = 114/281 (40%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 1851 NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 1901

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 1902 NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1938

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+ ++R +    +   L   +    + I +  +SD+G+  CVA N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQIIDIESAQISDAGIYKCVAIN 1995

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1996 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +  A+ SD   Y C A N AG
Sbjct: 2051 P-VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 2090



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 13/177 (7%)

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            V  D  V    + + +C   G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 1553 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 1609

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
            +SDS   TC   N +G       ++V      V P      +T LN  V     + L  +
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECK 1664

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P+P +TW KDGVP+  N  +RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 12/168 (7%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 4236

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G
Sbjct: 4292 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 4315

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K    + V+E          PP F     +  +    G
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE----------PPVFKGDYPSNWIEPLGG 4365

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 4366 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 4421

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 4422 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 4464

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 4465 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 4520



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 52/187 (27%), Positives = 81/187 (43%), Gaps = 11/187 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+   + +++  T G      C  TG P P++ W +ND  I   + +++    + +  L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM----TSDGTLF 667

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V+ 
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVME 722

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N AG 
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGR 780

Query: 572 TATRARL 578
              +  L
Sbjct: 781 ATGKITL 787



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
            L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 1307 LTGREPGISILEDGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 1363

Query: 398  CQ---DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
             +   +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GKILKLFR 1420

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
             T  D+G  +C A N +G +     ++V+    ++   F    S +  R+   V L  + 
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD---VALECQV 1477

Query: 515  VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 1533

Query: 572  TATRARL 578
             A   +L
Sbjct: 1534 QAKDIKL 1540



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 909

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 966

Query: 570 GS 571
           G+
Sbjct: 967 GT 968



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 4426 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 4480

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 4481 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 4521



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG +    C  +G P P + W      +  D   ++ +  SG   L I+    SD+ +
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL-SGGRQLQISIAEKSDAAL 2266

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             +CVA N +G    +  L V  +  +         + + V  G+ + L     G P P +
Sbjct: 2267 YSCVASNVAGTAKKEYNLQVYIRPTIT--NSGSHPTEIIVTRGKSISLECEVQGIPPPTV 2324

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            TW KDG P+I    + I  +G    L +     SD   Y C A NVAG T
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAVNVAGMT 2372



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 4314

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G   F   +  +  ++   P F   + +  +   G   +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG---FVKAIGFVYVKE--PPVFKGDYPSNWIEPLGGNAIL 4369

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/345 (22%), Positives = 130/345 (37%), Gaps = 37/345 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I +V + D   +  +A +  GT +      V E          PP       NV VT 
Sbjct: 484  LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE----------PPPVIQVPNNVTVTP 533

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L   +      ++ W +N + V+     +I       +L +      D+G+Y C+
Sbjct: 534  GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCM 592

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              +  G +       V                  PP++    K++    G  +   C   
Sbjct: 593  VSSEGGSSAASVFLTVQ----------------EPPKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P P + W   D  I  S  ++M  T+D  TL I  A P+D G Y C+A NSAG     
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRM--TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            + L+  +  +      +    +++V  G     + + +    P ++W +    +   P  
Sbjct: 694  STLRYIEAPK-----LMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPST 746

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +I +    +L I  T + D G +TC A   AG+      L V S
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D  V     T   C     P   +TWF +   +  + N +IL    G   L I N    
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQED 2639

Query: 459  DSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            ++G  +CVA N++GE      + V     I K  +  P    +   + ++    + L   
Sbjct: 2640 NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE 2697

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   P+  ++W KDG P+  +  + I  +G   TL I  A+ SD   Y C A N+AG
Sbjct: 2698 AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAG 2752



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 3762 ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 3876

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 3877 TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 3932 KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 74/294 (25%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            +G+         G P P + W ++GQ L   + H  ++TH    L++   +  DSG YT 
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG-MVLQLLKAETEDSGKYTC 3506

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            +A N  G +     L V  P           +I  +++ E     EIS     P     C
Sbjct: 3507 IASNEAGEVSKHFILKVLEP----------PHINGSEEHE-----EISVIVNNP-LELTC 3550

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                +   KMT       GRP P+        Q++            G   L I+   + 
Sbjct: 3551 IASGIPAPKMTWMK---DGRPLPQTD------QVQ---------TLGGGEVLRISTAQVE 3592

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G  TC+A + +G+   +  + V     +         + L  R+   V L  ++   P
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ---VTLECKSDAVP 3649

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P ITW ++G  +   P +RI +  G   L I  A   D A Y C A N+AG T
Sbjct: 3650 PPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGKT 3701



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L I  V   D+G  TC+
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQIAFVQPGDAGHYTCM 4149

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 4150 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4204

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 4205 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 61/277 (22%), Positives = 112/277 (40%), Gaps = 28/277 (10%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            ++   V    P  + +++NG  +  D   + L+E  +  L I +    D G YEC+A++S
Sbjct: 448  QIPCSVDSLLPFTLSFVRNGVTLGVD---QYLKESASVNLDIAKVTLSDEGFYECIAVSS 504

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG  R      VS                 PP +I+   +  V  G+    +C I+    
Sbjct: 505  AGTGRAQTFFDVS----------------EPPPVIQVPNNVTVTPGERAVLTCLIISAVD 548

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
              + W + D+ ++ ++  ++ RT    +L +      D G+Y C+  +  G    +  L 
Sbjct: 549  YNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            V +P +   +P     ++     G         T   KP I W      I  +  ++M  
Sbjct: 608  VQEPPKVTVMP-----KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            +G    L I N   +D G + C A+ +AG  + ++ L
Sbjct: 663  DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 12/201 (5%)

Query: 402  DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
            +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 955

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 956  GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 1010

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             + W K G  +I     +  + G   +L +      ++  Y CTA N AG    + +L  
Sbjct: 1011 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068

Query: 581  XXXXXXXXXQKRLHLPRPTKV 601
                     Q+ L   +P ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEI 1089



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 12/188 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++V  +  VT G+     C +       +TW  NDR +R        +    N +L 
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVL 510
           + +V  +D+G   C+  ++ G +A    L V E  +V V PK        +   G  V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK------NQSFTGGSEVSI 631

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P+I W  + + I+ +   R+ +DG   TL I  A   DA  Y C A N AG
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688

Query: 571 STATRARL 578
           +    + L
Sbjct: 689 TDKQNSTL 696



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N+ G+++    L   
Sbjct: 2996 LSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   EC    V  P   I WY NG+ +  ST ++ 
Sbjct: 3054 VPPSIKDHDSESLSVVNV---REGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEI 3108

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 3109 LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 104/477 (21%), Positives = 174/477 (36%), Gaps = 55/477 (11%)

Query: 99   PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            P P ++W +   PL   +K  +      G   L I +    D G YTC A N+ GE    
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLIL----PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860

Query: 159  ----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                V + P                 + S  +E  + G+        +  Q +   +   
Sbjct: 2861 YDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--H 2918

Query: 215  HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
            H    + ++       + ++     + +   G +    +  +      V P  I  K  N
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-----VPPSVIGPKSEN 2973

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
              +          ++SG P P ++W KN Q  I  N + +I      TL++   + SD G
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQP-IKLNTNTLIVPGGR-TLQIIRAKVSDGG 3031

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERIEISEKALAPQ 393
             YT +A N  G       L V  P    ++D  S+ ++    RE T   +E    A+ P 
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSLECESNAVPPP 3089

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
             +   ++     G+M      +T   + E+   + D Q+   +  K  V+++G +     
Sbjct: 3090 VITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVSDTGQYVCRAI 3133

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV               +G       LNV     +  P+      T++     PV L   
Sbjct: 3134 NV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS----NPVTLTCD 3174

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C A N+ G
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 4432 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 4482

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 4483 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 4531



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C+  G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 1718

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  I
Sbjct: 1719 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 1776 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 1812



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 1238

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
             TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 1239 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 1296

Query: 521  RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W  +G  +    P + I  DG  + L I      D   Y C A N AG+T  +  L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 14/157 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA----EISVK 3137
            I WF +G  +E++  IR +   G   L+IL  +  ++G YSC ATN+ G+     E+ V 
Sbjct: 2607 ITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVY 2664

Query: 3138 L-ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +   ++K     P  +   + ++ +K   +   EC    +  P   + WY +GQP++   
Sbjct: 2665 IPPIINKGDLWGPGLSP--KEVK-IKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDD 2719

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +   ++ G   L I   Q  D+G Y C A N  GED
Sbjct: 2720 HVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGED 2754



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 62/288 (21%), Positives = 104/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 4132

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 4133 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4192

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 4193 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 4250

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 4251 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 4303

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +   G++ V+ P
Sbjct: 4304 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 3515

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 3516 SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3569

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 3570 PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 3608



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +  S  IR + A G V+  I+  + +D   Y+C A+N+ G    
Sbjct: 3367 TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYTCVASNRAGVDNK 3424

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L+            T  I  ++    G S    C       P M   W  +GQP+  
Sbjct: 3425 HYNLQVFAPPNMDNSMGTEEITVLK----GSSTSMACITDGTPAPSM--AWLRDGQPLGL 3478

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + TVS  G +VL +   +  DSG+Y C A N+ GE
Sbjct: 3479 DAHL-TVSTHG-MVLQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 17/203 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +L+IL T+ TD G Y C A N  G A+   ++ +       G K    T + N       
Sbjct: 2927 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN------- 2979

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                  C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C
Sbjct: 2980 NFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTC 3035

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----E 3280
             A N+ GE   + ++  Y    +     +  S+  +RE  S+    +     P      +
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3095

Query: 3281 PPKFITQIQDVTKLVEGQSAHFE 3303
              + IT+   V  L +GQ  H +
Sbjct: 3096 NGRMITESTHVEILADGQMLHIK 3118



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 64/257 (24%), Positives = 98/257 (38%), Gaps = 22/257 (8%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P + W +K +P++  +   +R    +G   L I      D   Y+C A N  G A 
Sbjct: 2222 GIPPPNLIWKKKGSPVLTDSMGRVRI--LSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279

Query: 157  ----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
                  VYI+P                R  S ++E +  G    T    +    +    G
Sbjct: 2280 KEYNLQVYIRPT-ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG 2338

Query: 213  TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES-DVQISTEIDRSLGPVSPPKIA-- 269
             +            E  +L+  +   S T RYV  + +V   T+    L   +PP I   
Sbjct: 2339 VEILD---------EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389

Query: 270  -QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             + P N  + E        + SG P P +TWFK+G  +  SN   I++      LR+  T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQT 2447

Query: 329  QKSDSGHYTLLAENPNG 345
               D+G YT +  N  G
Sbjct: 2448 TMEDAGQYTCVVRNAAG 2464



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 3728 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 3784

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 3785 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 3883



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           + ES +  L I  VTLSD G   C+A + +G    Q   +V E      P  ++  + + 
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE-----PPPVIQVPNNVT 530

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V  GE  VL    +      +TWQ++   +      RI T    S L++   K +DA  Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEY 589

Query: 562 QCTAQNVAGSTA 573
            C   +  GS+A
Sbjct: 590 HCMVSSEGGSSA 601



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 260  LGPVSPPKIAQKP--RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            L  + PP I  +    + K++E        +++GNP P +TW K+GQ L     H II+ 
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS- 2530

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L++ N Q   +G YT LA +P G
Sbjct: 2531 -GGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 86/218 (39%), Gaps = 35/218 (16%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            ++ IK       E     I  ++L   W KDG+P+++   +    N G+  L IK   + 
Sbjct: 2683 EVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQIS 2738

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEV 1037
            D G YTC A N  G+     ++ I          Q P   +K+  + +     +  E + 
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI----------QVPPSFQKLWEIGNMLDTGRNGEAKD 2788

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD 1097
             I   P                S + E    P   LT    WY +G  +TS++++     
Sbjct: 2789 VIINNP---------------ISLYCETNAAPPPTLT----WYKDGHPLTSSDKVLILP- 2828

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G   L I   + ED+G YT VA N AGE  L   + V
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 74/293 (25%), Positives = 118/293 (40%), Gaps = 46/293 (15%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   + WY +G+ L+      + ++ G  TL + +    D+G YTC A N  GE      
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGEDELDFD 2759

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            V            Q P   + L +I N+ D             TGR  E     KD++ I
Sbjct: 2760 V----------NIQVPPSFQKLWEIGNMLD-------------TGRNGEA----KDVI-I 2791

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +     + E +  P       + W+ +G  + +S ++  +   G  VL+I   K  D+G 
Sbjct: 2792 NNPISLYCETNAAPPP----TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGR 2845

Query: 3121 YSCRATNKWGQ--AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            Y+C A N+ G+   +  V++      KG        +  +      +SA  EC  +    
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLV----NKSALIEC--LSSGS 2899

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P  +  W  +GQP+      K +S+    +L I  TQ  D G YVC A N  G
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAG 2950



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 66/168 (39%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 4012 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4069

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 4070 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 4121

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L IA+ Q  D+G Y C A N  G   T   +  +
Sbjct: 4122 SIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 3236 YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 3287

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 3288 ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 4431

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG P+T+S ++  I   G V L I   + EDAG YT  AVN+ GE      
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVL-ILPGGRV-LQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862

Query: 860  IRVAARSTVT-ADLGIPEQ 877
            +RV     +  A+  +PE+
Sbjct: 2863 VRVLVPPIIKGANSDLPEE 2881



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   N   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 4404

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 4405 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 1311

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 1312 PGISILEDG-TLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            ++   EC++  +  P   V W  +G PL+ K +   I D G++ +    ++  D+G Y+C
Sbjct: 2308 KSISLECEVQGIPPPT--VTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSDTGRYVC 2363

Query: 4049 RATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
             A N+ GM + K  +     P I+ + + P+++  +EK
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 4194 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 4250 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 4300

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V     I        P      P N  
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWI 4360

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 4361 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 4417

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 2104 PNIMGEEQN 2112



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 18/164 (10%)

Query: 3079 SMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            S  + W+ +G+ +++   +  + A G   L+I   + +D+G Y+C A+N  G+ E+   +
Sbjct: 2703 SASLSWYKDGQPLKSDDHVN-IAANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV--PVD-------DPDMKIEWYHNG 3189
                    QK      I N+  L  G++   +  ++  P+         P   + WY +G
Sbjct: 2761 NIQVPPSFQK---LWEIGNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG 2815

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+  S ++  +   G  VL I   +  D+G Y C A N+ GED
Sbjct: 2816 HPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 3255 DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 3312

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            D+G YTC ATN  GE      L V     +     +    EK+  L DTS
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTI---RGNKDEAEKLMTLVDTS 3359



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  +  N     GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 4402

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  N   I  SHR R   + G + ++    K  D+G Y C A+N  G  + 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQ 692

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            +  L  ++  K         +Q+   +  G     EC    +  P +K  W+     +R 
Sbjct: 693  NSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGIPPPQVK--WFKGDLELRP 744

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLE 3250
            ST +  + D    +L I  TQ+ D+G+Y C A N+ G    + T++  G   V+++
Sbjct: 745  STFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD-VGSPPVFIQ 797



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 1170 PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 1268

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 1269 ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 1308

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 1309 GREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 1368 TNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 4078 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 4131

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 15/197 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP    V  ++  ++ G+ A     +I   D ++   W  N + +  +   R +  
Sbjct: 515  DVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLT--WQRNDRDVRLAEPAR-IRT 570

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               + LE+   K  D+G Y C  +++ G +  SV L        Q+P   T +   +   
Sbjct: 571  LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV------QEPPKVTVMPKNQSFT 624

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G      C+      P  KI W  N   +  S R +  SD    + + A     D+G Y
Sbjct: 625  GGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAA---PKDAGIY 679

Query: 3223 VCRAYNKYGEDFTRATI 3239
             C A N  G D   +T+
Sbjct: 680  GCLASNSAGTDKQNSTL 696



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PP    +P   +   G      C  TG+PKP++ W +N   IV   RY++T DG
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 4489 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 4544

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 4545 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGK 875



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 756  LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 809

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 810  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 870  ENQFGKIQSETTVTVTG 886



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 789  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 849  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 1371 SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDA 1426

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST-QNEAG--LEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +   NE    L +   LE + K      + 
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 1486

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 1487 WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C        A+T    G  I+ S +++Y++      
Sbjct: 1546 PSIKGGNVTTDI-SVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 1604

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 1605 IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++ +    + G   L +      D G Y C A +  GE
Sbjct: 1664 KAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV      +L++      D+G YSC+A N  G ++  
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVN--NGKILKLFRATPEDAGRYSCKAINIAGTSQKY 1443

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +           T+  N   +   +    EC V     PD  I W+ +G+P+   
Sbjct: 1444 FNIDVL----VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLG 1497

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 1498 DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +    G  I  E  ++ +  PT  + W+K+G  +   ++   I   G+I L + ++++ D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSD 2357

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
            +G Y C AV+  G+ + K  L V    +I    + PE +  +++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 35/210 (16%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++++  N     E     +  P   + W ++G P+++ + +    + G+  L +K    
Sbjct: 2682 KEVKIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQI 2737

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G YTC A N  GE      + +Q   S Q        L +I  + D+ R    +DV 
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ-------KLWEIGNMLDTGRNGEAKDVI 2790

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +            N P  L         C     P P +   WY +G  L S  +     
Sbjct: 2791 I------------NNPISL--------YCETNAAPPPTL--TWYKDGHPLTSSDKVLILP 2828

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
              G   L I     ED+G YTC A+N  G+
Sbjct: 2829 --GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 57/266 (21%), Positives = 102/266 (38%), Gaps = 11/266 (4%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            L GNP P   W +  A L++    ++R      D SL I+++   D GEYTC A N  G 
Sbjct: 914  LAGNPIPERRWIKNSAMLLQNPYITVR-----SDGSLHIERVQLQDGGEYTCVASNVAGT 968

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               +  +                    +  T+  KA G    +   S++ + ++ ++   
Sbjct: 969  NNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF 1028

Query: 215  HSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
             +  D    V +       E     + T  Y  +  VQ++  +   +          KP 
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYA-KRKVQLTVYVRPRVFGDQRGLSQDKPV 1087

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSD 332
               +  G +     ++   P P +TW K  Q +   S +H  + + +   +++  T+ SD
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSD 1144

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESP 358
            SG Y  +A N  G +  +  L V  P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVP 1170



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 3652 VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 3710 NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 3759

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 3760 YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 3801



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 3952

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 3996



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +G  +  S+ +R +   G  +L ++ T   D+G Y+C   N  G+      L  +
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P        +E +K  +      T     +P  +I W+ +GQP++       +
Sbjct: 2476 ------VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII 2529

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S   F  L I   Q   +G Y C A +  G      ++N +
Sbjct: 2530 SGGRF--LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2568



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  EC+   V      + W+KNG+ +T       + D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHL 3145



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 3299

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+  L 
Sbjct: 3300 NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTLV 3356

Query: 1960 DDS 1962
            D S
Sbjct: 3357 DTS 3359



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 4252 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 4306

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 4307 VN--GHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     S+ +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 4400

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     ED+G YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1385 CQATNQLGEAVTSCALRVIAKKDLILE 1411
            C ATN+ G    S +L + +   + LE
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 4364 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 4419 CVATNEAGVVERSMSLTLQS 4438



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    + KN  F  G          G P P ++WT     +V  ++Y M     T D +
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM-----TSDGT 665

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L IK   P D G Y C A N  G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAG 688



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I +  G     E  ++ I   T  V W+KDG P+  +  +    + G++ L +K++ V 
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI-LQLKNIHVS 2356

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            D G Y C A N  G      +L++     II   + P  +  ++
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G  +L I  V   DAGHYTC A N  G ++TS  LT+
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 1252 TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 1305

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 1306 ELTGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPII 1392



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 3676

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++ N    D+ +YT +A N  G       L V  P
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 3712



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 4429 ERSMSLTLQSPPIITLE 4445



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 20/170 (11%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDI---------IDESVTIKPRFVTRPKSIE 1454
            AK   IL+  H   L+ I ++ DT RY    +          D SV   P  +   +S E
Sbjct: 2336 AKGVEILDEGHILQLKNI-HVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE 2394

Query: 1455 N--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            N  V+E   V   C+   +   +  + WFK+G PV++ +  R +   G   L ++    E
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPS--ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTME 2450

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            D+G YTC   N  G +     L+      IV     E  LE ++V E +S
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLVPPHIV----GENTLEDVKVKEKQS 2496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632  RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 3429 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 3485

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
              G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 3486 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 3518

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 3519 FILKVLEPPHINGSEEHE 3536



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 3605 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 3655

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 3656 LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 3700



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 3766

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 3767 F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 12/174 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C ATN  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 1188

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 1189 DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 1244

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P
Sbjct: 1245 NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKP 1296



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 1579 ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 1635

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +  I+  
Sbjct: 1636 YVPPMIEGNLATPLN--KQVVIAHSLTLECKA--AGNPSPILTWLKDGVPVKANDNIRI- 1690

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 1691 -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG PV  S+ +      G   L +   T+ DAG YTC   NA G+      L+++
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 1003 TKKDIIAES 1011
                I+ E+
Sbjct: 2476 VPPHIVGEN 2484



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 3257 SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++  L D S
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTLVDTS 3359



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 1216

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 1217 HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 1256



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T   ++ S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 1496

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 1497 GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I V  G  +  +C V+ +  PT  + W  +G P      V  L++ G I L +  I+  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GHI-LQLKNIHVSD 2357

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
             G Y C A N  G       ++  A   I+   + P+ +S
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS 2397



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 3261 GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 3319 CVATNPAG 3326



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 4131

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 4132 --SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P+ +    N     G+ V + C     G    ++ W  N   I   HR+R   +
Sbjct: 606  LTVQEPPKVTVMPKNQSFTGGSEVSIMC--SATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI-AKKDLILESQHPSGLEKIQY 1423
                 L + +  P+D+G+Y C A+N  G    +  LR I A K ++++S+    L  I  
Sbjct: 664  G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITV 720

Query: 1424 LE 1425
            +E
Sbjct: 721  ME 722



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 714 ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 769

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 770 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 826

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 881

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 938

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAG 967



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 1351 YNLKVHVPPVIKDKEQ-------VTNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 1400

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 1401 VTESSTIQTVNN--GKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+  IR + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 1725 YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLIDE 1777

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 1778 RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 1813



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEK 2092

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 2093 QRDIDLRV 2100



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 633  VYPPPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V+ PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTN--TLIVP 3015

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            G  +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   V  EC  E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 3071 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 3127 QYVCRAINVAGRD 3139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LEC    +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 4433 SLTLQS 4438



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 860  IRVAARSTVTADLGIPEQRRYI 881
            + V     +  +L  P  ++ +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVV 1654



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ + + +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 2003

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 2004 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 2053

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +   Q  D+G Y C A N  GE
Sbjct: 2054 SFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVNAAGE 2091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G+ +  EC+++ +      V W K+G P+ I  +   I D G++ L + ++   D+G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSDTG 2359

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             Y C AVN+ G  +    L+  +   I+    N    E I V+E  S
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSII---GNHRSPENISVVEKNS 2403



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G++   E ++  +  PT  V W KDG P+  +  +  I + G++ L + ++   D G Y 
Sbjct: 2307 GKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGV-EILDEGHI-LQLKNIHVSDTGRYV 2362

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
              AVN  G       + V A  ++  +   PE    +EK
Sbjct: 2363 CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   EC     P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 3073 EGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 3302 STLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)

Query: 3047 PPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP  +   K+ ++ + +      EA  +P  D    I W  +G+ I  S R R V + G 
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPD----ITWHKDGRAIVESIRQR-VLSSGS 4132

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LK 3162
              L+I   +  D+G Y+C A N  G +  S KL     +    PR    I++ EG   + 
Sbjct: 4133 --LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL-----TVHVPPR----IRSTEGHYTVN 4181

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +   A   C    +  P   I W  +   + +     T   +G ++L+    +  DSG Y
Sbjct: 4182 ENSQAILPCVADGIPTP--AINWKKDNVLLANLLGKYTAEPYGELILENVVLE--DSGFY 4237

Query: 3223 VCRAYNKYGED 3233
             C A N  GED
Sbjct: 4238 TCVANNAAGED 4248



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 788  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 900

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 901  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 956

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 957  EYTCVASNVAG 967



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 1351 YNLKVHVPP 1359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 84/375 (22%), Positives = 143/375 (38%), Gaps = 32/375 (8%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            +NI V E   V   C  E  G P   I WF +G P +  + V  L+  G   L +     
Sbjct: 2394 ENISVVEKNSVSLTC--EASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTM 2449

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+YTC   N  G       ++      IV E+ L      EK        ++  P  
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E       + + + ++H +    G RF  ++   + P      Y      P+GH+ R+  
Sbjct: 2510 EITWHKDGQPLQEDEAHHI--ISGGRF-LQITNVQVP--HTGRYTCLASSPAGHKSRSFS 2564

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVND------FGEDFTKATISCKKLPDIILQNQVPR- 3935
               FVS  I  V ++ + E +   +N           +  ATI+  K    +  N+  R 
Sbjct: 2565 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI 2624

Query: 3936 --GMKRSEALTQMEATIKKYTSEVYLTEDDL---YDVDKKQPP------RFVTQIQSQTS 3984
              G +  + L   E    +Y+        ++   Y+V    PP       +   +  +  
Sbjct: 2625 LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEV 2684

Query: 3985 LVEMETT-KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
             +++  T   EC+   +  P+  + W+ +G+PL   +    I   G+  +        D+
Sbjct: 2685 KIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVN-IAANGH-TLQIKEAQISDT 2740

Query: 4044 GEYLCRATNLYGMDE 4058
            G Y C A+N+ G DE
Sbjct: 2741 GRYTCVASNIAGEDE 2755



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 4429 ERSMSLTLQS 4438



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 87/402 (21%), Positives = 156/402 (38%), Gaps = 41/402 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 791  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 966

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 967  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 1023

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDQRGLS 1082

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 1137

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +    DSG+Y C A N+ G    + +L       I R  ++
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 1544 IPPSIKGGNVTTDI----SVLINSLIKLECETRGLPMP--AITWYKDGQPIMSSSQALYI 1597

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 1598 -DKG-QYLHIPRAQVSDSATYTCHVANVAG 1625



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 2063

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 2064 GGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V  GK+   EC+V+ +  P   + +  +G  L  A    I  D G++ L +++    D G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTG 2359

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             Y   A+N  G       ++V A  SII   + PE +  + +   +   +   IP P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 3261 GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDT--QNEQAIEQIQLLEDAA 1295
              A N  G        R+   +  VT T   N+   E++  L D +
Sbjct: 3319 CVATNPAGEED-----RIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 3359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S      G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 4399

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL+L+S   +   +   +  S        V + V + P+ +T +      + G      C
Sbjct: 575  SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMC 633

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P  ++ W  N   +   HRYR ++D     L I     +D+G Y C A N+ G
Sbjct: 634  SATGYPKP--KIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 1927 QAVSSIRLN-VQSKESIIRDSQHESALEKIQYLE 1959
                +  L  +++ + ++  S+   AL  I  +E
Sbjct: 689  TDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 897  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 952

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 953  QDGGEYTCVASNVAG 967



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 1224

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
             +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 1225 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 1907

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY + + +
Sbjct: 1908 QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNRLL 1961

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1962 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1998



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +   + +D+G Y+C A N  G+ +  + L   
Sbjct: 2043 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVY 2101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 2102 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 2152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S+    VL I   Q  D+G Y C A N  G+      +N +
Sbjct: 2153 SE-NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 54/211 (25%), Positives = 82/211 (38%), Gaps = 34/211 (16%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            S K V+IK       E     +  A+L   WY + +PLKS        N G   L I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASLS--WYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSA 1702
               D+G YTC         V S IA    +    +  Q   +  +L ++ +     R+  
Sbjct: 2736 QISDTGRYTC---------VASNIA-GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
              +VI   P+           E  AA           P   + W ++G P+ +S+++  +
Sbjct: 2786 AKDVIINNPISLY-------CETNAA-----------PPPTLTWYKDGHPLTSSDKVLIL 2827

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G   L +     ED+G YTC A+NE GE
Sbjct: 2828 P--GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633  VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 3052 VYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTH-VEI 3108

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
               G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 3109 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 3154



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 3126

Query: 842  SYTVRAVNKLG 852
             Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             NL +     I          EK+  L D S
Sbjct: 3332 FNLNVYVTPTIRGNKDE---AEKLMTLVDTS 3359



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS+ I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 4403

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 4404 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 4461

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 4462 QATGEPQPTIT 4472



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 18/270 (6%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 1102 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATNIAG 1157

Query: 154  EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
                +V +                        +   A GT       S+    +   +G 
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 1216

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
             H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 1217 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 1269

Query: 272  PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
            P N+  QE    Q   F     G P+P + W  NG+ L    +  I    + T L + + 
Sbjct: 1270 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEDGTLLVIASV 1328

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               D+G Y  +A N  G       L V  P
Sbjct: 1329 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 22/283 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 1225

Query: 131  LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
            L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 188  H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                A GT        + T K  + NG + +  +       +  LL   S        Y+
Sbjct: 1286 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337

Query: 246  GESDVQI-STEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
              +  +  +TE   +L    PP I  K +  N  +          ++ G P P + W+K+
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 1398 NVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ I+     + +     +V  I   + +++G Y C A N  G    
Sbjct: 1759 TGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKK 1816

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 1817 EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 1865

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 1866 PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 724  AVLHVTPRATIE 735
              LHV    ++E
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQIS--DTGRYTCVAVNAAGEKQR 2094

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 2095 DIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P+++I++   S   EC +  +   +  V W  +G PL+    V+ +++ G  IL++  ++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GH-ILQLKNIH 2354

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
              D G Y C A N  G       L V     II   + P +
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            +L++     +D+G Y C A N  G  +    L      S     R   +I  +E  K+  
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE--KNSV 2404

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   E + +P+      I W+ +G P+  S  ++ +S  G  +L +  T   D+G+Y C 
Sbjct: 2405 SLTCEASGIPLPS----ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCV 2458

Query: 3226 AYNKYGED 3233
              N  GE+
Sbjct: 2459 VRNAAGEE 2466



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 34/215 (15%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+    +   EC  E Y  P+  + WY +G+ L+S      + + G   L I      D+
Sbjct: 2685 KIKVNNTLTLEC--EAYAIPSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDT 2740

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G YTC A N  G+      +N+Q   S          L +I  + D  R   A       
Sbjct: 2741 GRYTCVASNIAGEDELDFDVNIQVPPSF-------QKLWEIGNMLDTGRNGEA------- 2786

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
                         +V   +P+ L         PT+   WY +G P+      K     G 
Sbjct: 2787 ------------KDVIINNPISLYCETNAAPPPTL--TWYKDGHPLTSSD--KVLILPGG 2830

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              L I  A  ED G Y C A N  GE      V+V
Sbjct: 2831 RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 3122

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 3123 SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 3170

Query: 3548 LTPEAESGNPP 3558
            LT +A +G PP
Sbjct: 3171 LTCDA-TGIPP 3180



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 785  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 843

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 844  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 1006 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 1063

Query: 724  AVL--HVTPR 731
              L  +V PR
Sbjct: 1064 VQLTVYVRPR 1073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTV-NNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 860  IRVAARSTV 868
            I V    T+
Sbjct: 1446 IDVLVPPTI 1454



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+  +   +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 1510

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1952 ITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 2010 VAPSISGSN 2018



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            +++  + V   P      + PT++  + G+S   EC ++  P P   V W  +G  L   
Sbjct: 2279 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKA 2336

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                  ++     L +  ++  D+G Y C A+N  G       L+V +  SII    H S
Sbjct: 2337 KGVEILDEGHI--LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII--GNHRS 2392

Query: 1951 ALEKIQYLEDDS 1962
              E I  +E +S
Sbjct: 2393 P-ENISVVEKNS 2403



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +C    V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 3124

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 3125 TGQYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 3126

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626  PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 3661

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 3662 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 3529 EGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS 3588
            EG  + IA     +G   T    +E   PP     P+++ ++    A   C +I   D +
Sbjct: 494  EGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550

Query: 3589 MRVEWFHNGKP--LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            +   W  N +   L   +R++T+ +     LE+  V   DAG Y C  ++  G +  S  
Sbjct: 551  LT--WQRNDRDVRLAEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVF 605

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTE 3670
            L V+    + + P+  S F  G+E
Sbjct: 606  LTVQEPPKVTVMPKNQS-FTGGSE 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PPK     K+ +      V   C       PK +I W  N   +   HRYR   D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGY--PKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              +L I     +D+G Y C A N  G D   +T+   + P +++
Sbjct: 664  -GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 916 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 972

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 973 TSVVVHVLP--TIQHGQQILSTIEGI 996



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P+++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 1446 IDVLVPPTIIG-----TNFPNEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 1496

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 1497 GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 1405 KKDLILESQ-HPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            +K +I ++Q   +GL +         +KK    + +V + P   +   S   V++ + V 
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVA 1845

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
             +C    +   N  + W K+ QPV        I   G V L I   + ED+G YTC A N
Sbjct: 1846 LQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902

Query: 1524 LVGTDEVSCRL 1534
              G  +   +L
Sbjct: 1903 AAGETQQHIQL 1913



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S P   + W+KDG P+ ++  I  +   G  +L I++ + ++AG Y+  A N+ GE I  
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658

Query: 858  ASIRV 862
              ++V
Sbjct: 2659 YEVKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+G  L +   ++     G  TL I + + D++G Y+C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2732 IKI 2734
            +K+
Sbjct: 2661 VKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +C    V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 860  IRVAARSTV 868
            + V    T+
Sbjct: 3334 LNVYVTPTI 3342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 3829 GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 3886

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 3887 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 3945

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 3946 ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 3998

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 4056

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQVP 4078



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 4126

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 4127 VLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 791  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 850  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 994  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 1003 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 1058

Query: 154  EA----ICSVYIQP 163
             A      +VY++P
Sbjct: 1059 YAKRKVQLTVYVRP 1072



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/179 (21%), Positives = 72/179 (40%), Gaps = 7/179 (3%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W   G  +      R     G   L+I   + +D+  YSC A+N  G A+    L+    
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY-- 2287

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             +       +H   I  +  G+S   EC V  +  P   + W  +G P+  +  ++ + D
Sbjct: 2288 IRPTITNSGSHPTEII-VTRGKSISLECEVQGIPPP--TVTWMKDGHPLIKAKGVE-ILD 2343

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
             G  +L +      D+G YVC A N  G    +  ++ +    +      P++++ + +
Sbjct: 2344 EGH-ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E  + P  TI WF +G  + +    R     G   L IL    +++G Y C ATN+ GE 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 2194 VNTCTLKV 2201
            +    +KV
Sbjct: 2656 IKHYEVKV 2663



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIH--FETRIE----PVGDPTMKIEWLKNGQSI 679
            P GEEDR++    ++ P       E  K+    +T I       G P  +I WLKNG  +
Sbjct: 3324 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 3383

Query: 680  EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
              SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 3384 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 3421



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 3728 KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 3784 MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 3795

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 3796 IDLQVHVPP 3804



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 4151 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 4204

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 4205 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 1253 EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 1304

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 1305 RELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 1346



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 1259 QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 1312

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 1313 GISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 1354



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 653  KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            K+  ETR    G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC 
Sbjct: 1566 KLECETR----GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCH 1619

Query: 713  AVSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
              +  G AE    + V     IE     P   Q +
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 1654



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284  QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
            + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 1623

Query: 344  NGCIVTSGYLAVESP 358
             G    S ++ V  P
Sbjct: 1624 AGTAEKSFHVDVYVP 1638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+ + +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 2003

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 2004 YSLQVHVAP 2012



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKDG P+     ++   N     L I+   V D G YTC A N  G+   + N+ I
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ WY +G+ + S + +    + G+  L I   +  D+G YT VA N AGE +L   + +
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            +   S       + L+E          +  M       ++K V +   +NP        I
Sbjct: 2763 QVPPSF------QKLWE----------IGNMLDTGRNGEAKDVII---NNP--------I 2795

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C       PT+   W+ +G  +T  S  K     G   L I  A   D G YT  AV
Sbjct: 2796 SLYCETNAAPPPTL--TWYKDGHPLT--SSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851

Query: 1256 NHLGSAHTSAIVRVI 1270
            N  G       VRV+
Sbjct: 2852 NEAGEDSLQYDVRVL 2866



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 3253 PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 3309 ALTSDTGKYTCVATNPAGE 3327



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 3469 WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 3526

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 3527 PHINGSEEH 3535



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 3523 VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 3580

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 3581 GEVLRISTAQVEDTGRYTCLASSPAGD 3607



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 3767

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 4197 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254

Query: 1134 TV 1135
            TV
Sbjct: 4255 TV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 4268 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 4321

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G     G
Sbjct: 4322 DSGTYVCTAENSVGFVKAIG 4341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 4451 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 4506

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 4507 FECVARNLMG 4516



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  KI W  N+  +    RY+ T D +   L I +   +D+GIY C A+NS G+   + +
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 2863 LR 2864
            LR
Sbjct: 696  LR 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 994  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 1106

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 1107 PPPIITWAK 1115



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 265  PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP I     P    +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 1509

Query: 323  LRVRNTQKSDSGHYTLLAENPNG 345
            L ++N +++D G Y     N  G
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 7/149 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            SH   I+   G +I  EC V+    PT  + W  +  PL      +   D  ++ L + +
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKN 2352

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
             +  D+G Y C A N  G       L      +I  + + P+    +  VE+   +   +
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE---NISVVEKNSVSLTCE 2409

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEG 2926
                 +P   + K  W + ++   +++ G
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSG 2438



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   + W+ +G P++     +     G   L IL A  ++ G Y C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2067 VKV 2069
            VKV
Sbjct: 2661 VKV 2663



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 3124

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 3242 QVPPSVAGAEI 3252



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 3439 SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 3494

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 3535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 4100 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSS 4157

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 4158 STSTKLTVHVPPR--IRSTEGH 4177



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 4194 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 4251

Query: 997  ANLTI 1001
             +LT+
Sbjct: 4252 VSLTV 4256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 6/142 (4%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
            Q  + +    L I++    DEG Y+C+A +SAG         V++P     +P      +
Sbjct: 474  QYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVP-----NN 528

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V  G+ A     I S +   + W R    +    +   I    N  L + +    D G
Sbjct: 529  VTVTPGERAVLTCLIISAVDYNLTWQRNDRDV-RLAEPARIRTLANLSLELKSVKFNDAG 587

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C  ++  G    S  L V+
Sbjct: 588  EYHCMVSSEGGSSAASVFLTVQ 609



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK ++ W  N + I  S+R     D     L +K   P+D+G Y C A N  G    +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 1798 STL-FVQSKASLQLESQHESALQKIQQLE 1825
            STL ++++   + ++S+   AL  I  +E
Sbjct: 694  STLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 775  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449

Query: 1003 TKKDII 1008
                II
Sbjct: 1450 VPPTII 1455



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 3833 ITQIKSHTVE----ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            IT   SH  E      + +  EC V+    P   + W ++G  L        + D G + 
Sbjct: 2292 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI- 2347

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGM 3937
            L +  ++  D+G Y+C AVN  G    K  +S    P II  ++ P  +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2396



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            P   + WF +G  L      R     G   L IL   E+N+G Y CVATN+ G
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            DV    P+   C       PT+   W+ +G P  +  +V  L   G   L I      DA
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDA 2843

Query: 3766 GEYTCRATNKWG 3777
            G YTC A N+ G
Sbjct: 2844 GRYTCVAVNEAG 2855



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL TL D+ +
Sbjct: 3334 L------NVYVTPTI-RGNKDEAEKLMTLVDTSI 3360



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 3581

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 3685

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 3686 -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3744

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 3745 TWRKDGAVLAGNHARYSILENGFLHI---QSAH 3774



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L IA V+  D+G YT +A N AG +  S  +TV 
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAI 4187



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP + Q P N  +  G  A     +       +TW +N + +  +    I T  N  +L 
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLE 577

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
           +++ + +D+G Y  +  +  G    S +L V+ P +  V  +   +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSF 623



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 790  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 847  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 897  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 951

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 952  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 1236

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQE 1260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFET-RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            VY PP     L +    +    H  T   +  G+P+  + WLK+G  ++A+         
Sbjct: 1635 VYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR--IEA 1692

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
            G   L+++S    D G+Y C A S  G  E K  + V     IE
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 1736



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 2039 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDID 2097

Query: 860  IRV 862
            +RV
Sbjct: 2098 LRV 2100



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 2099 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 2156

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              + ++     +QD+G YTC A +  G  E
Sbjct: 2157 SVLKIE--DAQVQDTGRYTCEATNVAGKTE 2184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R+  NI  VE  +V L C     G     + WF +G P+   +  R         L L+ 
Sbjct: 2391 RSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQ 2446

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
               ED+G YTC   N  GE      L V+    ++ E+
Sbjct: 2447 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN 2484



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W+KDG P++ S+ +  I + G + L +M    EDAG YT    N  GE
Sbjct: 2414 PLPSITWFKDGWPVSLSNSV-RILSGGRM-LRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P+  + WYKDG+P+ +   +    N G+ +L I   +  D G YT  A N  GE
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGE 2753



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG P+ +S ++      G   L I    V DAG YTC A N  G+ +   ++ ++
Sbjct: 2811 WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+ N++EG     EC    +  P +T  W+ NG+ I          D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPVIT--WYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2177 EDSGTYMCKATNKLG 2191
             D+G Y+C+A N  G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 3147 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
               L +      DSG YTC A +  G A+
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 3449 KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 3504

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3536



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 3769

Query: 325  VRNTQKSDSGHYTLLAENPNG 345
            +++   +D+G Y  +A N  G
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAG 3790



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 4106 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162

Query: 860  IRV 862
            + V
Sbjct: 4163 LTV 4165



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 4419 CVATNEAGVVERS 4431



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 4427 VVERSMSL 4434



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 4433 SLTLQSPPIITLEPVE 4448



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKI 876



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + W KD R +  S+ +T F N G + + I+S  + DAG Y C A N+ G
Sbjct: 1952 ITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +  A  +DTG YT  A
Sbjct: 2029 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVA 2085

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 3261 GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTS 4160

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 4161 TKLTVHVPPRIRSTEGHYTVNENSQAI 4187



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP--FATGSR 3743
            T  D    PP   +++ +N+ V  G      C +    D    + W  N R    A  +R
Sbjct: 512  TFFDVSEPPP--VIQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPAR 567

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            + TL +   ++L++  +   DAGEY C  +++ GS+  +  +T
Sbjct: 568  IRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 700  EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 754

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 755  GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 798



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 1236

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTV 1264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++ +LL SG    T  + G + +DI      
Sbjct: 1929 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNRLL-SGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1985 DAGIYKCVAINSAG 1998



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 1176 KPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +P      S+P    V+ GK+I LEC ++ +  PT  V W  +G  +      +   +  
Sbjct: 2289 RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGH 2346

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
             + L  IH   +DTG Y   AVN  G       + V     I+ + ++ + I  ++
Sbjct: 2347 ILQLKNIHV--SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+ E QS    C +   P P   + W+ +G+ LQ    +   +   F  L I  V    +
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPE--ITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545

Query: 1915 GEYTCKAINNLGQAVSSIRLNV 1936
            G YTC A +  G    S  LNV
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNV 2567



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P D+ +  NS     C       ++  + WF +G PL +   ++ +   G   L+I    
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPAT--ITWFKDGTPLESNRNIRILP--GGRTLQILNAQ 2637

Query: 3624 QRDAGLYTCKATNRHGE 3640
            + +AG Y+C ATN  GE
Sbjct: 2638 EDNAGRYSCVATNEAGE 2654



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 51/193 (26%), Positives = 78/193 (40%), Gaps = 41/193 (21%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            P+  + W+ +G+P  +   V+   + G   L I      D G YTC A+N          
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASN---------- 2749

Query: 3785 ITCSAKRDIVLESQLPQGMSGEKIKE----LERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            I    + D  +  Q+P   S +K+ E    L+ GR  +A  ++ I++ P           
Sbjct: 2750 IAGEDELDFDVNIQVPP--SFQKLWEIGNMLDTGRNGEA--KDVIINNP----------- 2794

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
                  +   C       P L   WY++G  L S  +   +   G V L I     ED+G
Sbjct: 2795 ------ISLYCETNAAPPPTLT--WYKDGHPLTSSDKV-LILPGGRV-LQIPRAKVEDAG 2844

Query: 3901 EYICRAVNDFGED 3913
             Y C AVN+ GED
Sbjct: 2845 RYTCVAVNEAGED 2857



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+I++   S + E    P       + W+ +G PL +  +V  +   G  +L+I      
Sbjct: 2788 DVIINNPISLYCETNAAP----PPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVE 2841

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            DAG YTC A N  GE ++   ++V
Sbjct: 2842 DAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T+  T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 3354 TLVDTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 3409

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3519

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 3520 ILKV-------LEPPHINGSEEHEEI 3538



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 4438 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4494

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 4495 YIADAQ---KEDTSEFECVARNLMGS 4517



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P+     KN   T G  V +  + T    P  ++ W  N   +   HR++ T D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG- 664

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
               L I  A  +D G Y C A+N+ G     S+++
Sbjct: 665  --TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI W  N   +    R+++TSD    TL + +   +D+GIY C A N  G    +ST
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 3001 V 3001
            +
Sbjct: 696  L 696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 756

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 757  -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 794  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 854  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICV 1339

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 1340 AVNEAGTTERKYNLKV 1355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAG 1345



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   P  + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNF---PNEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 1493

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 1471 VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 1527

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 1528 SNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915

Query: 1136 ETRSSID 1142
                S++
Sbjct: 1916 HEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G  + LE  +  +  PT  V W  +G P+ +    +   D G++ L +   +  DTG
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTG 2359

Query: 2049 TYMCKATNAVG 2059
             Y+C A N  G
Sbjct: 2360 RYVCVAVNVAG 2370



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 8/144 (5%)

Query: 3962 DDLYDVDKKQPPRFVTQIQS--QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            D  YD+    PP  +   +S    S+VE  +    C+ +  G P   + WF +G P+   
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLS 2430

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
            N    +   G   +       ED+G+Y C   N  G +     +     P IV ++ L +
Sbjct: 2431 NSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-E 2487

Query: 4080 HMKSIEKIREMEASWQVTPEQVVE 4103
             +K  EK + +  + +VT   V E
Sbjct: 2488 DVKVKEK-QSVTLTCEVTGNPVPE 2510



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + W+ +G  L+S    R     G   L IL    +++G Y+C A N  G+ 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 1929 VSSIRLNV 1936
            +    + V
Sbjct: 2656 IKHYEVKV 2663



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV 3622
            +P ++ +  N++   EC    +  +S+   W+ +G+PL +   V    + G   L+I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 3623 YQRDAGLYTCKATNRHGE 3640
               D G YTC A+N  GE
Sbjct: 2736 QISDTGRYTCVASNIAGE 2753



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDL 1509
            PK ++  +    +  EC+   +  ++L   W+K+GQP+        I   G+  L I + 
Sbjct: 2681 PKEVKIKVNNT-LTLECEAYAIPSASLS--WYKDGQPLKSDDHVN-IAANGHT-LQIKEA 2735

Query: 1510 IAEDSGIYTCRAVNLVGTDEV 1530
               D+G YTC A N+ G DE+
Sbjct: 2736 QISDTGRYTCVASNIAGEDEL 2756



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/120 (30%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            EDS +Y  R  V   +  A    + L     +   +SA  EC     P P  R  W  +G
Sbjct: 2856 EDSLQYDVRVLVPPIIKGAN---SDLPEEVTVLVNKSALIECLSSGSPAP--RNSWQKDG 2910

Query: 1885 K-VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            + +L+  H    SN      L IL     D G Y C A N  G A     LNV    S+I
Sbjct: 2911 QPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2967



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 2986 CEVSGFPPPDL--SWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 3041

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 3042 GESKKKFSLTVYVPPS-IKDHDSES 3065



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 8/151 (5%)

Query: 2194 VNTCTLKVAGHRNI-ILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV---TELR 2249
            +NT TL V G R + I+  +  +G E       Q   ++ +       PP      +E  
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESL 3066

Query: 2250 GTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
               +V EG +   EC+   V  P   I +Y NG+ +  +    I  D G + L I+    
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
             D G+Y  +AIN  G       + V    SI
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 3447 VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 3502

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 3503 KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 3674

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 3675 RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 3722



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 3979

Query: 724  AVLHV 728
              LHV
Sbjct: 3980 VTLHV 3984



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 14/133 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 4217 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 4268

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 4269 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 4322

Query: 3219 SGEYVCRAYNKYG 3231
            SG YVC A N  G
Sbjct: 4323 SGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W +N + +    R+R T D    TL I +    DAG+Y C A N AG
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V    PV  +C+    G+P   I W+ + R   +GS   T  + G I +DI+     
Sbjct: 1929 NETVLVSNPVQLECKA--AGNPVPVITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3764 DAGEYTCRATNKWGS 3778
            DAG Y C A N  G+
Sbjct: 1985 DAGIYKCVAINSAGA 1999



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 3826 VSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNEQ--PIKLNTNTLIVP 3015

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            G  +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN+ GE+   
Sbjct: 2990 GFPPPDLSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 3108 ILADGQMLH 3116



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 2996 LSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 1003 TKKDI 1007
                I
Sbjct: 3054 VPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 724  AVLHVTPRATIERTSQHPETL 744
              L+V    TI       E L
Sbjct: 3332 FNLNVYVTPTIRGNKDEAEKL 3352



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 1791 LGE 1793
             G+
Sbjct: 3605 AGD 3607



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 3712 PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 3768

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 3769 HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 3887

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 3888 TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 3936

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 3937 LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 3985



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 3952

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 3993



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 4260 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 4312

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  +T +   ++   G      C       P +   W  N   I   HRYR T D   
Sbjct: 609  QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDMFIVGSHRYRMTSD--- 663

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
              L I     +D+G Y C A+N  G      TL+
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 1273 TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVT 1329

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 1330 PYDNGEYICVAVNEAGTTERKYNLKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 3510 MKV 3512
            +KV
Sbjct: 1353 LKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAG 1438



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 1671 SKKSI 1675
               S+
Sbjct: 1917 EPPSL 1921



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1946 GNPVPVITWYKDN-RLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L  +T +EG  I      E  G P   + W K G  +   S        G   L +    
Sbjct: 2203 LTQLTVIEGNLISL--LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE 2260

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
              D+  Y+C A +  G A+ +  L V  R TI  +  HP
Sbjct: 2261 KSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHP 2299



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG  + L  +      PNL   W K G  + T +  +     G   L I+     D+ 
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLI--WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2265

Query: 2714 IYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            +Y+C A+N+ G A    ++++  R  +     HP  +
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W+++G P+  +  +  + D G++ L +K ++  D+G Y C A+N  G     
Sbjct: 2318 GIPPPTVTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2375

Query: 1798 STLFVQSKASL 1808
              L V +  S+
Sbjct: 2376 YDLSVHAPPSI 2386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P   + W ++G P+E++  +  +   G   L +     +++G Y+C A NE GE +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 2963 PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GG 3017

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 3430

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 3431 FAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 3791



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 3744 ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3801

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 3802 VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 3852

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 3853 YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 4260 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 4312

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 945  WLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            W ++ R V  +  +RI T  N   ++L +KSV  +DAG Y C   +  G +  S  LT+ 
Sbjct: 553  WQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 1002 -VTKKDIIAESQHPGGLEKIQYLEDASRYSK 1031
               K  ++ ++Q   G  ++  +  A+ Y K
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPK 640



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    PK+ ++   G  V   C          K+ W  N   +   HR+R   D     
Sbjct: 612  PKVTVMPKN-QSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG---T 665

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L I +   +D+GIY C A N  GTD+ +  L
Sbjct: 666  LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            +T+T+   +   + +  + A    Q  + + V   P+  R   +++   G  V + C  Q
Sbjct: 1137 ITETRTSDSGMYLCVATNIAGNVTQAVK-LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G     + W   G  +        +     +++D  +  P D+G+YTC ATN  G   
Sbjct: 1196 --GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT--PSDAGIYTCVATNIAGTDE 1251

Query: 1396 TSCALRV 1402
            T   L V
Sbjct: 1252 TEITLHV 1258



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            +L C +E  G P+  + W+ +   VT  S  +T  + G + L +  AT  D G Y+ +A+
Sbjct: 1379 NLFCEVE--GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAI 1434

Query: 1256 NHLGSAHTSAIVRVIERSDIV-TDTQNEQAI 1285
            N  G++     + V+    I+ T+  NE ++
Sbjct: 1435 NIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 1465



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   + WYKD R ++ S+ +T   N G + ++I   +  DAG Y   A+N  G      
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 859  SIRVAARSTVT 869
            S++V    +++
Sbjct: 2005 SLQVHVAPSIS 2015



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ID  V + P  +   +++ +V+  Q V   C+ + +    L   W K+G P+ +      
Sbjct: 2096 IDLRVYVPPNIMGEEQNV-SVLISQAVELLCQSDAIPPPTLT--WLKDGHPL-LKKPGLS 2151

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            I +   V L I D   +D+G YTC A N+ G  E
Sbjct: 2152 ISENRSV-LKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3694 PPRFTVE-IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP    E   +++ V E   V   C V   G+P   I W  +G+P       H ++   F
Sbjct: 2477 PPHIVGENTLEDVKVKEKQSVTLTCEV--TGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2534

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I  +     G YTC A++  G
Sbjct: 2535 --LQITNVQVPHTGRYTCLASSPAG 2557



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  + E    P+  + W+K+G  L +   +    +    TL I   +  D+G YTC A+N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASN 2749

Query: 2722 LLGE 2725
            + GE
Sbjct: 2750 IAGE 2753



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 2/72 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KDG+P+        F + G + L I +  + D G Y C A N  G A   
Sbjct: 2898 GSPAPRNSWQKDGQPLLEDDH-HKFLSNGRI-LQILNTQITDIGRYVCVAENTAGSAKKY 2955

Query: 997  ANLTIVTKKDII 1008
             NL +     +I
Sbjct: 2956 FNLNVHVPPSVI 2967



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 14/146 (9%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYVALDLLSVY 1376
            N+  V    + L C +   G     + W  N +PIK  T     P        L ++   
Sbjct: 2973 NLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTNTLIVPGGR----TLQIIRAK 3026

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              D G YTC A NQ GE+    +L V       ++      L  +   E TS      + 
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTS----VSLE 3080

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHV 1462
             ES  + P  +T  K+   + E  HV
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHV 3106



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 3073 EGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 3129 VCRAINVAG 3137



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W +N K IE+S  +      G   + I+  +  D G Y C ASN+ G+
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 3318

Query: 146  CTARNQYGE 154
            C A N  GE
Sbjct: 3319 CVATNPAGE 3327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 3357 DTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 3412

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 3413 CVASNRAGVDNKHYNLQV 3430



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 3556 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613

Query: 860  IRV 862
            +RV
Sbjct: 3614 VRV 3616



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 3728 KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 3782

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  +G+ ++   R + ++      L+I  V   DAG YTC A N  G ++ S KL V
Sbjct: 4110 ITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 4364 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 4418

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 4419 CVATNEAG 4426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPP   VP  +VT   G +      I    D    + W +N + +  +     I     +
Sbjct: 519 PPPVIQVP-NNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEP-ARIRTLANL 574

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQ 739
           SL++ S+   D+GEY C   S  G +     L V   P+ T+   +Q
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 702  PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 757

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 758  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 799



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 1007 NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 1063

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 1064 VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 1118

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 1119 LISPFSPRH 1127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 1253

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQE 1277



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +E  P P   + WY +   +      +T N+     L +     ED+G Y+CKAIN  
Sbjct: 1382 CEVEGTPSPI--IMWYKDNVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIA 1437

Query: 1926 GQAVSSIRLNVQSKESII 1943
            G +     ++V    +II
Sbjct: 1438 GTSQKYFNIDVLVPPTII 1455



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1844 PRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            P  I   N P ++S    +    EC+++  P P+  + W+ +GK L  G       D G 
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRG- 1507

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L +      D G Y C   N  G+    I+L +    SI
Sbjct: 1508 QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 1548



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+     +   + G   L+I+ A   
Sbjct: 1650 NKQVVIAHSLTLECKAA--GNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEI 1705

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 1838 VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 1894

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 1895 RYTCVATNAAGE 1906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 1912

Query: 2199 LKV 2201
            L V
Sbjct: 1913 LHV 1915



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 2001 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 2057

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 2058 GLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 2109



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V   +PV LE     +  P++   W  +G PV            G + L +  A   DTG
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLT--WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTG 2079

Query: 2049 TYMCKATNAVGE 2060
             Y C A NA GE
Sbjct: 2080 RYTCVAVNAAGE 2091



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 2034 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVN 2087

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 2088 AAGEKQRDIDLRV 2100



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  + + Q+ + L+  +  +  CQ   +  P +   W  +G PLL K   +   +   +
Sbjct: 2103 PPNIMGEEQNVSVLIS-QAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENRSVL 2159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V  +D+G Y C ATN+ G  E    +     P I
Sbjct: 2160 KIEDAQV--QDTGRYTCEATNVAGKTEKNYNVNIWVPPNI 2197



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G ++ LEC +Q +   T  V W  +G P+          E     L L +++  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSD 2357

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            +G Y C A N  G       L V A   +I   + P  +  ++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P   + W ++G P+  SN +  +   G   L +     ED+G YTC   N  GE
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P ++ +  N SA  EC  +     + R  W  +G+PLL     K +++    IL+I    
Sbjct: 2879 PEEVTVLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQ 2934

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQV 3649
              D G Y C A N  G A     L V
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNV 2960



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/71 (33%), Positives = 31/71 (43%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N   IE S+ L      G   L +      DSG YTC A N  G+A   
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 1798 STLFVQSKASL 1808
              L +Q   S+
Sbjct: 3237 YFLSIQVPPSV 3247



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 4165 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 4222

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 4223 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 4426


>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
          Length = 5635

 Score =  129 bits (312), Expect = 2e-28
 Identities = 107/384 (27%), Positives = 161/384 (41%), Gaps = 35/384 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  ++ A  E    G P P   W ++  P+      +    S   IL I    + D   +
Sbjct: 2884 VLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRILQILNTQITDIGRY 2941

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGT 4540
              VAEN  G+AK   NL V           VPPS     ++N+ V     + L  +V+G 
Sbjct: 2942 VCVAENTAGSAKKYFNLNVH----------VPPSVIGPKSENLTVVVNNFISLTCEVSGF 2991

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P D+ WLKN + ++ +    I+   G  TL I+ A   D G+Y C+AIN AGE++    
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V +P       P  K  ++     E L    V EG ++   C+    P P + WYK  
Sbjct: 3050 LTVYVP-------PSIKDHDS-----ESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3097

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            ++I  S + ++   AD   L I +A   D G Y C A N AGR      L V  P   + 
Sbjct: 3098 RMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155

Query: 4721 LPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                 P R+++V     P       T    PTI WL+    I  +   ++      + L 
Sbjct: 3156 -----PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVE 4803
            I  +   D+G +TC A+   G+ +
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQ 3234



 Score =  119 bits (287), Expect = 2e-25
 Identities = 103/380 (27%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 1148

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 1149 LCVATNIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 1257 HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 1305

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   D   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 1306 EL--TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               +T   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 1364 KEQVT---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKL 1418

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 1419 FRATPEDAGRYSCKAINIAG 1438



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/371 (27%), Positives = 155/371 (41%), Gaps = 39/371 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + W R +  ++ +   +I T +  S L ++ V   D+  +  +  + GG++  S  L V+
Sbjct: 551  LTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E          PP  T+  +N + T G  V +    TG     + W  N   +    R +
Sbjct: 610  E----------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYR 659

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             +  DGT  L I  A P+D+G Y C+A NSAG                DK     +   A
Sbjct: 660  -MTSDGT--LFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEA 701

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P +++    + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+
Sbjct: 702  P-KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLK 758

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I E    D GDY CVA N AGR T    L V  P      PA     D+ +  G      
Sbjct: 759  IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLP 813

Query: 4742 TQITSKIKPTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              +    +PTI+W R +   I   P     I +     L I N +  D GT+ C A    
Sbjct: 814  CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 4800 GQVETSAKLVV 4810
            G++++   + V
Sbjct: 874  GKIQSETTVTV 884



 Score =  115 bits (276), Expect = 5e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 4237

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 4238 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 4287

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 4288 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 4344 YVKEP-------PVFKG-DYPSNWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 4388

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 4389 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 4441

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 4442 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 4497

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 4498 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score =  113 bits (271), Expect = 2e-23
 Identities = 103/405 (25%), Positives = 158/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 1227

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 1282

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + EDGT  L+I    P D+G+Y CVA+
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAV 1341

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDK---------------EQVTNVSVLLNQLTNLFCEVEG 1386

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 1387 TPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P      ++ V   +    + Q+     P I W ++G  L    P
Sbjct: 1445 NIDVLVPPTIIGTNFP-----NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 1500 NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  110 bits (264), Expect = 1e-22
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI-VPGGRTLQI 3022

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N+ G +K   +L V           VPPS     + +   VNV
Sbjct: 3023 IR-AKVSDGGEYTCIAINQAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 3071

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 3129

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 3174

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 3235 KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  109 bits (261), Expect = 3e-22
 Identities = 100/368 (27%), Positives = 151/368 (41%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 3271 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 3330

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         TL   ++N+        + + TGT P  + WLKNG  
Sbjct: 3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI--------ECRATGTPPPQINWLKNGLP 3382

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 3383 LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 3438

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 3439 ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 3486

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 3487 HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 3541

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 3542 VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 3598

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 3599 CLASSPAG 3606



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 3054 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI--LAD 3111

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 3112 GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 3161

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 3267

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 3268 CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L  +V         + + T    P I WL+ G  +P
Sbjct: 3328 EDRIFNLNVYVTPTIRGNKDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLP 3384

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 3385 LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 3420



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/407 (25%), Positives = 164/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 4043

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 4093

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMA 4150

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 4151 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 4194

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 4195 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 4250 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 4301

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+    + VK
Sbjct: 4302 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346



 Score =  106 bits (255), Expect = 2e-21
 Identities = 91/382 (23%), Positives = 165/382 (43%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P++ W ++  P+K + + +I     K  ++  Q    D   +  VA +  G
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAG 1719

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWL 4548
              +    + V          +VPP+     +     V    L+ LD  VTG+ P  + WL
Sbjct: 1720 EKEIKYEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWL 1769

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P  
Sbjct: 1770 KDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP-- 1825

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  K++         L +++V + + +   C   G P P++ W K D+ +  ++ 
Sbjct: 1826 -----PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ- 1871

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              +   +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L 
Sbjct: 1872 GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LN 1929

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            + V+    P Q + +      P I W ++  L+  +     ++ G   ++ I +    D 
Sbjct: 1930 ETVLV-SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDA 1986

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A  +AG  E    L V
Sbjct: 1987 GIYKCVAINSAGATELFYSLQV 2008



 Score =  105 bits (253), Expect = 3e-21
 Identities = 122/485 (25%), Positives = 195/485 (40%), Gaps = 59/485 (12%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            ++ G P P +SW + + P+    K +       G  +L I +    D GEYTC A NQ G
Sbjct: 2987 EVSGFPPPDLSWLKNEQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 154  EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
            E+      +VY+ P                   S ++E ++                  Y
Sbjct: 3043 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITW--------Y 3094

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
             NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 3095 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 3152

Query: 268  IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
            I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 3153 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIA 3212

Query: 327  NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 3213 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 3253

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                         D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 3254 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREG 505
            +  L I     SD+G  TCVA N +GE      LNV     +   K   E+  TL     
Sbjct: 3302 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTL---VD 3357

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              + +  RA GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A
Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVA 3415

Query: 566  QNVAG 570
             N AG
Sbjct: 3416 SNRAG 3420



 Score =  105 bits (252), Expect = 4e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 3420

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 3421 VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 3471 RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 3526

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 3527 -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 3573

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 3574 -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 3629

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 3687

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 3688 ANYTCVASNIAGKTTREFILTV 3709



 Score =  105 bits (251), Expect = 5e-21
 Identities = 101/395 (25%), Positives = 161/395 (40%), Gaps = 35/395 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP    + Q   V   +      + D  P P + W ++  P+   P   I     +S+L 
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTS 4527
            I    V+D+  +   A N  G  + + N+ +           VPP+   + +   + V  
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW----------VPPNIGGSDELTQLTVIE 2210

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G L+ L  + +G  P ++ W K G  V  D   ++    G   L I  A   D+  Y CV
Sbjct: 2211 GNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCV 2270

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG A+ +    V +  T       T + + P EI       IV  G++I   C++ 
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPT------ITNSGSHPTEI-------IVTRGKSISLECEVQ 2317

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PTV W K G  LIK +K  ++    + + L++      D G Y CVA N AG    
Sbjct: 2318 GIPPPTVTWMKDGHPLIK-AKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2374

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V  P     +       +I V E        + +    P+I W ++G  +  +  
Sbjct: 2375 KYDLSVHAPPSI--IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNS 2432

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +++  G   +L +  T  ED G +TC    AAG+
Sbjct: 2433 VRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score =  104 bits (250), Expect = 7e-21
 Identities = 109/409 (26%), Positives = 167/409 (40%), Gaps = 41/409 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 850

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 851  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 902

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 903  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 959

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 960  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 1003

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSS-AKFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYAK 1061

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +   L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V
Sbjct: 1122 PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score =  104 bits (250), Expect = 7e-21
 Identities = 96/377 (25%), Positives = 155/377 (41%), Gaps = 34/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P  +W + +  +  +P   + +  +   L I +V ++D   +  VA N  GT   +
Sbjct: 916  GNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT 972

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             ++VV           V P+     Q ++   G  V L  K +G     V W K G+ + 
Sbjct: 973  TSVVVH----------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                      DG+  L ++    ++SG+Y C A N+AG A+   +  V +       +P+
Sbjct: 1023 TSSAKFSAGADGS--LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYV-------RPR 1073

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT- 4674
                       +P++  ++A G+ +   C++   P P + W K  +LI P   F    T 
Sbjct: 1074 VFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITWAKETQLISP---FSPRHTF 1129

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +++I+E    D G Y CVA N AG VT A KL V  P +    P     + + V  
Sbjct: 1130 LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQV 1184

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            GQ             P I W + G+ +    D +      +  L I      D G +TC 
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCV 1242

Query: 4795 ATTAAGQVETSAKLVVK 4811
            AT  AG  ET   L V+
Sbjct: 1243 ATNIAGTDETEITLHVQ 1259



 Score =  104 bits (250), Expect = 7e-21
 Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKE 1817

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 1818 FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 1868 NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 1919

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK ++L+  S    M+  
Sbjct: 1920 SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFL 1970

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1971 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 2025

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +    DTG +TC 
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSAQISDTGRYTCV 2084

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 2085 AVNAAGEKQRDIDLRV 2100



 Score =  104 bits (250), Expect = 7e-21
 Identities = 102/369 (27%), Positives = 147/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W + +  I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 3237 YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 3286

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 3287 IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 3339

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +  L D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 3340 PTIRGNKDEAEKLMTLVDT------SINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 3391

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 3392 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 3448

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3506

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 3507 IASNEAGEV 3515



 Score =  104 bits (249), Expect = 9e-21
 Identities = 101/398 (25%), Positives = 164/398 (41%), Gaps = 40/398 (10%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVF 4474
            KM    V      + E +  G P+P+I WY++N  +  S      TF  +  +I I    
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSM---TFLNRGQIIDIESAQ 1982

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + D+ ++  VA N  G  +   +L V           V PS + +   V V     VRL+
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH----------VAPSISGSNNMVAVVVNNPVRLE 2032

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +  G     + WLK+G  V     N +    G   L +  A   D+G+Y CVA+N+AGE
Sbjct: 2033 CEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             + D +  V +                PP I+   ++  V   QA+E  C+    P PT+
Sbjct: 2092 KQRDIDLRVYV----------------PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135

Query: 4655 QWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             W K G  L+K      +S + +   L+I +A  +D G Y C A N AG+      + + 
Sbjct: 2136 TWLKDGHPLLKKP---GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHE 4772
             P    N+     L  + V EG       + +    P + W ++G+ ++ ++     I  
Sbjct: 2193 VP---PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS 2249

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G    L I    + D   ++C A+  AG  +    L V
Sbjct: 2250 GGRQ-LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286



 Score =  102 bits (245), Expect = 3e-20
 Identities = 96/389 (24%), Positives = 155/389 (39%), Gaps = 31/389 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  +   R E E  G P P + W ++  P+ +  +  +   S   IL +    + D+  +
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRY 2081

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G  +   +L V           VPP+     QNV+V   Q V L  +     
Sbjct: 2082 TCVAVNAAGEKQRDIDLRV----------YVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  + WLK+G  +       I E      L I +A  QD+G+Y C A N AG+   +   
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNVAGKTEKNYNV 2189

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             + +P       P    +       + L    V EG  I   C+  G P P + W K   
Sbjct: 2190 NIWVP-------PNIGGS-------DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +      ++   +    L+IS A   D   Y CVA N AG       L+V       N 
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
             +     +I+V  G+    + ++     PT+ W+++G  + +    +++ EG+  +L + 
Sbjct: 2296 GSHPT--EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQLK 2351

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            N +  DTG + C A   AG  +    L V
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380



 Score =  101 bits (243), Expect = 5e-20
 Identities = 101/380 (26%), Positives = 148/380 (38%), Gaps = 35/380 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 1006 GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPGG-EESGEYVCTATNTAGYAKRK 1063

Query: 4496 ANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V  + R    + G+           ++V +G+ V L  +V    P  + W K  + 
Sbjct: 1064 VQLTVYVRPRVFGDQRGLSQDK----PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 1119

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P          G+  + I E    DSG Y CVA N AG      +  V          
Sbjct: 1120 ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV---------- 1167

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S 
Sbjct: 1168 ------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIV 4731
               + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V
Sbjct: 1222 P--DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 1279

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                Q  +F        KPTI+WL  G  L    P   ++ +G   +L+I +    D G 
Sbjct: 1280 A--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGE 1335

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A   AG  E    L V
Sbjct: 1336 YICVAVNEAGTTERKYNLKV 1355



 Score =  101 bits (241), Expect = 8e-20
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 3912

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 3970

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 3971 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 4013

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 4014 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 4071

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 4072 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 4126 RVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 1242 VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 1293

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 1294 PKPTIKWLHNGRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 1353 LKVH----------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 1400

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 1453

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 1506

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 1507 GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 1561

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 1562 NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 1619

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 1620 VANVAGTAEKS 1630



 Score =  100 bits (239), Expect = 1e-19
 Identities = 106/423 (25%), Positives = 169/423 (39%), Gaps = 31/423 (7%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKK-MQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T +   A  +ER + G      P I  +  ++  +V E +      E  G P+P I W++
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK 2515

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRR 4505
            +  P++   D   H  S    L I  V V  +  +  +A +  G    S +L V      
Sbjct: 2516 DGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
             G G    P      ++V V       L  +     P  + W K+G  ++ +   +IL  
Sbjct: 2574 AGVGSDGNP------EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL-- 2625

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             G  TL IL A   ++G+Y CVA N AGE     E  V +P   +K         +P E+
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL-SPKEV 2684

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
                K K+      +   C+    P  ++ WYK  + +K   +  ++  A+ +TL+I EA
Sbjct: 2685 ----KIKV---NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA--ANGHTLQIKEA 2735

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-------VVYEGQPA 4738
               D G Y CVA N AG   +   + +  P     L  +  + D         V    P 
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +  +   PT+ W ++G   P T   +++      VL I     ED G +TC A   
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNE 2853

Query: 4799 AGQ 4801
            AG+
Sbjct: 2854 AGE 2856



 Score =   99 bits (238), Expect = 2e-19
 Identities = 82/299 (27%), Positives = 123/299 (41%), Gaps = 40/299 (13%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P    +  G     + ++ G P P VTW K+G  LI +   EI+    H  L+++N   S
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGH-ILQLKNIHVS 2356

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            D+G Y  +A N  G       L+V +P  S + + RS                       
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHRS----------------------- 2392

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ + V +   V+        C  +G P P +TWF +   +    + +IL   SG   L 
Sbjct: 2393 PENISVVEKNSVS------LTCEASGIPLPSITWFKDGWPVSLSNSVRIL---SGGRMLR 2443

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +   T+ D+G  TCV RN +GE      L+V+    +V    +E    + V+E + V L 
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE---DVKVKEKQSVTLT 2500

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG P+    +   H   G   L I   +      Y C A + AG
Sbjct: 2501 CEVTGNPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 35/375 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E E  G P P + W ++  P+  +   +I       IL ++ + V D+  +  VA N  G
Sbjct: 2313 ECEVQGIPPPTVTWMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT---LTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
                  +L V            PPS      + +N++V     V L  + +G     + W
Sbjct: 2371 MTDKKYDLSVH----------APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITW 2420

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G  V   + N +    G   L +++   +D+G+Y CV  N+AGE R      V +P 
Sbjct: 2421 FKDGWPVS--LSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP- 2477

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                  P     N        L+D  V E Q++  +C++ G P+P + W+K  + ++  +
Sbjct: 2478 ------PHIVGENT-------LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               +   +    L+I+       G Y C+A + AG  + +  L V        + +    
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
             D+ V    P     +  S    TI W ++G  +    + +++  G    +L  N  E++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL--NAQEDN 2640

Query: 4788 TGTFTCRATTAAGQV 4802
             G ++C AT  AG++
Sbjct: 2641 AGRYSCVATNEAGEM 2655



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 95/380 (25%), Positives = 157/380 (41%), Gaps = 34/380 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E +  P P + WY++  P+ +S    I       +L I +  VED+  +  VA N  G  
Sbjct: 2800 ETNAAPPPTLTWYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857

Query: 4493 KCSANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                ++ V+     +G    +P       + V V   +   ++   +G+      W K+G
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLP-------EEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2910

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            + +  D  +K L       L IL     D G+Y CVA N+AG A+               
Sbjct: 2911 QPLLEDDHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAK--------------- 2953

Query: 4612 PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             K      + PP +I P  + + V     I  +C++ G P P + W K ++ IK +    
Sbjct: 2954 -KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +       TL+I  A   D G+Y C+A N AG       L V  P    +  + + L  +
Sbjct: 3013 I--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-LSVV 3069

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG     + +  +   P I W + G +I E+   +++ +G   +L I      DTG 
Sbjct: 3070 NVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQ 3127

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + CRA   AG+ + +  L V
Sbjct: 3128 YVCRAINVAGRDDKNFHLNV 3147



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 88/301 (29%), Positives = 127/301 (42%), Gaps = 37/301 (12%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 1051

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 1052 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 1090

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 1091 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 1143

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 579  Y 579
            +
Sbjct: 1257 H 1257



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF 4137

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 4138 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 4184

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 4185 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 4241

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 4242 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 4286 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKAIG 4341

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 4394

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 4395 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 88/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 1227

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 1268

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 1269 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 1318

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
             G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ + ++V  
Sbjct: 1319 DGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVTNVSVLL 1374

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 1375 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCK 1432

Query: 565  AQNVAGST 572
            A N+AG++
Sbjct: 1433 AINIAGTS 1440



 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 96/388 (24%), Positives = 160/388 (41%), Gaps = 36/388 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E        E  G PLP I W+++ +P+  S   +I   S   +L + Q  +ED+  +
Sbjct: 2398 VVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRMLRLMQTTMEDAGQY 2455

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTG 4539
              V  N  G          EE++  G   +VPP      T ++V V   Q V L  +VTG
Sbjct: 2456 TCVVRNAAG----------EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                ++ W K+G+ +Q D  + I+   G   L I       +G+Y C+A + AG      
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
               V +      P      ++  PE      D  V         C+    P  T+ W+K 
Sbjct: 2564 SLNVFV-----SPTIAGVGSDGNPE------DVTVILNSPTSLVCEAYSYPPATITWFKD 2612

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP---D 4716
               ++ ++  ++       TL+I  A  ++ G Y CVA N AG +    ++KV  P   +
Sbjct: 2613 GTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2670

Query: 4717 QADNL-PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
            + D   P L+P +++ +        + +  +    ++ W ++G   P   D  +    N 
Sbjct: 2671 KGDLWGPGLSP-KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ--PLKSDDHVNIAANG 2727

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              L I      DTG +TC A+  AG+ E
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDE 2755



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 64/209 (30%), Positives = 88/209 (42%), Gaps = 8/209 (3%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYP 421
            +   QY    +    EER       L P  +      +D  V E +     C VTG P P
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            E+TW  + + +++D  H I+   SG   L ITNV +  +G  TC+A + +G  +    LN
Sbjct: 2510 EITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V     +           + V    P  L   A   P   ITW KDG P+  N  +RI  
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2626

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G  TL I  A+  +A  Y C A N AG
Sbjct: 2627 --GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 3896

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 3951

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 4006

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 4007 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 4065 GTALGKIKL 4073



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 99/397 (24%), Positives = 159/397 (40%), Gaps = 41/397 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N  V  
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1934

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+ + +        L       + I  A   D+G Y+CV
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1992

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1993 AINSAGA----TELFYSL------------QVHVAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++ A   D G Y CVA N+AG    
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 2095 DIDLRVYVPPN-----IMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              +    N +VL I +   +DTG +TC AT  AG+ E
Sbjct: 2150 LSI--SENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 96/379 (25%), Positives = 156/379 (41%), Gaps = 42/379 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W   +  I  S  +++ +  T   L I+    +D+ ++  +A N  GT K +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            + L   E           P   +    + V  G +  ++ K +G  P  V W K   +++
Sbjct: 694  STLRYIEA----------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P   +  L  D    LL I E    D+G Y CVAIN AG A                   
Sbjct: 744  P---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI--------------- 785

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             T    +PP  I+   D  +  G  +   C + G P PT++W + D +   S+ F +S  
Sbjct: 786  -TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 4675 ADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +   T  L I   +  D+G Y C A N  G+  + ++  VT       L  ++P    V+
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK--IQSETTVTVTGLVAPLIGISPSVANVI 902

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQ      T +     P  +W++  A++ + P   +  +G+   L I     +D G +
Sbjct: 903  -EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEY 958

Query: 4792 TCRATTAAGQVETSAKLVV 4810
            TC A+  AG    +  +VV
Sbjct: 959  TCVASNVAGTNNKTTSVVV 977



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 86/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ +  G     + W 
Sbjct: 1533 KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY 1582

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 1583 KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 1638

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   CK  G P P + W K    +K +  
Sbjct: 1639 -----PMIEG-----NLATPLNKQVVI-AHSLTLECKAAGNPSPILTWLKDGVPVKANDN 1687

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             ++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 1688 IRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 1742

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G LI E   F+++  G    L+I      +T
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNT 1800

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTV 1822



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V+G P P+++W  N++ I+ + N  I+    G   L I    +SD G  TC+A N++G
Sbjct: 2986 CEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 3043 ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3101

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 3102 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 3137



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 87/367 (23%), Positives = 146/367 (39%), Gaps = 17/367 (4%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W+++  P++++ + +I        L I     +++  ++ VA N  G       
Sbjct: 2603 PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V       +G +  P   L+ + V +     + L+ +        + W K+G+ ++ D
Sbjct: 2661 VKVYIPPIINKGDLWGPG--LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2718

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                I      +TL I EA   D+G+Y CVA N AGE   D +  + +P +  K      
Sbjct: 2719 DHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
              +         KD I+     I   C+    P PT+ WYK G  L    K   +     
Sbjct: 2777 MLDTGRN--GEAKDVII--NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PG 2829

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L+I  A  ED G Y CVA N AG  ++   ++V  P       +  P  ++ V   +
Sbjct: 2830 GRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP-EEVTVLVNK 2888

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  +   +    P   W ++G  + E    + +   N  +L I NT   D G + C A 
Sbjct: 2889 SALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRILQILNTQITDIGRYVCVAE 2946

Query: 4797 TAAGQVE 4803
              AG  +
Sbjct: 2947 NTAGSAK 2953



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 3607

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 3608 -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 3661

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 3662 LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 3712

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 3713 PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 3762

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 3763 LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 3815

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 3816 IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 3875

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 3876 CTVTNGAGDDKRTVDLTVQ 3894



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 3553 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 3602

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 3603 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 3640

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
              +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 3641 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 3696

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 3697 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 3752 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 4064

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 4065 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 4119

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 4120 VESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 1835 ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 1892

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 1893 AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1947

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1948 PVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 2000



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 13/217 (5%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
            R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  + + I +    KIL+N      L+I    +S++G+  C+A N +G+   +  + V 
Sbjct: 1767 MWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTD 542
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I + 
Sbjct: 1824 VPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSS 1879

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 1880 G--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 49/290 (16%)

Query: 293  PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGY 352
            P   +TWFK+G  L ++    I+      TL++ N Q+ ++G Y+ +A N  G ++    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            + V  P                       + ++    L+P+ VK+  +  +T       +
Sbjct: 2661 VKVYIPP-------------------IINKGDLWGPGLSPKEVKIKVNNTLT------LE 2695

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C     P   ++W+ + + ++ D +  I  N    H L I    +SD+G  TCVA N +G
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAG 2752

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNV----REGE--------PVVLNARAVGTPTP 520
            E      +N+      V P F + +   N+    R GE        P+ L       P P
Sbjct: 2753 EDELDFDVNI-----QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2807

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +TW KDG P+  + ++ I    G   L IPRAK  DA  Y C A N AG
Sbjct: 2808 TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAG 2855



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 52/350 (14%)

Query: 229 RLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGAD 282
           R L  +S   +S+     GE    +S+E   S   V      PPK+   P+N     G++
Sbjct: 569 RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSE 628

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
                  +G P+P++ W  N   ++ S+++ + +     TL ++N    D+G Y      
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY------ 679

Query: 343 PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
             GC+ ++      + T+              +Q  T   IE      AP+ + V  +  
Sbjct: 680 --GCLASNS-----AGTD--------------KQNSTLRYIE------APKLMVVQSELL 712

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L I      D+G 
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGD 769

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TCVA N++G    +  L+V        P F++  + +++  G  V L     G P P I
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI 824

Query: 523 TWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            W++ D +PI   P  +   +      L I    ASD   Y C A+N  G
Sbjct: 825 KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFG 874



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/302 (24%), Positives = 132/302 (43%), Gaps = 33/302 (10%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P+  K++       + +    P   ++W+K+GQ L  S+ H  I  + HT L+++  Q S
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANGHT-LQIKEAQIS 2738

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR--ETEERIEISEKA 389
            D+G YT        C+ ++  +A E   +  V  Q    +  + Q+  E    ++     
Sbjct: 2739 DTGRYT--------CVASN--IAGEDELDFDVNIQ----VPPSFQKLWEIGNMLDTGRNG 2784

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
             A         +DV         C     P P +TW+ +   +    + K+L+   G   
Sbjct: 2785 EA---------KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS--SDKVLILPGGR-V 2832

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I    + D+G  TCVA N++GE + Q  + V+    ++     +    + V   +  +
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSAL 2891

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +   + G+P PR +WQKDG P++ +   +  ++G    L I   + +D   Y C A+N A
Sbjct: 2892 IECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNG--RILQILNTQITDIGRYVCVAENTA 2949

Query: 570  GS 571
            GS
Sbjct: 2950 GS 2951



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/311 (23%), Positives = 128/311 (41%), Gaps = 40/311 (12%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 3304 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 3348

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               +EK +         D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 3349 ---AEKLMT------LVDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLL- 3392

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 3393 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 3448

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 3449 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 3505

Query: 563  CTAQNVAGSTA 573
            C A N AG  +
Sbjct: 3506 CIASNEAGEVS 3516



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 3625 TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 3682

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 3683 DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 3732

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 3790

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 3791 TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 3895 VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 3950 GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 3984



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 3769

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 3819

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 3880 NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 3923

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 3980

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 3981 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4035

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 4036 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 9/163 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 2030 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSAQISDTGRYTCVAVN 2087

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 2088 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 2142

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P++  P L I  +   S L I  A+  D   Y C A NVAG T
Sbjct: 2143 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKT 2183



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 722  ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 779

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 780  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 829

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 830  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 885

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 886  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 936  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 986

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 987  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPGGE 1044

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 60/204 (29%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 380  EERIEISEKALAPQFVK-----VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            E+ ++   + L P  +K     + ++  V   K    +C  +G P P  +W  + + + +
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
            D +HK L N      L I N  ++D G   CVA N +G       LNV     V+ PK  
Sbjct: 2916 DDHHKFLSN---GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-- 2970

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
                 L V     + L     G P P ++W K+  PI  N    I    G  TL I RAK
Sbjct: 2971 --SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAK 3026

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD   Y C A N AG +  +  L
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSL 3050



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 101/475 (21%), Positives = 177/475 (37%), Gaps = 49/475 (10%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W +   P V   + +++  + +G V  + K +   D G YTC A N  GE  
Sbjct: 1852 GIPNPSITWLKDDQP-VNTAQGNLKI-QSSGRVLQIAKTLLE-DAGRYTCVATNAAGETQ 1908

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              + +                    VS  V+ +           +        +  T  +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
              +  ++   E   + +    + +     G      +TE+  SL     P I+       
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAG------ATELFYSLQVHVAPSISGSNNMVA 2022

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +      + + +  G P P +TW K+G   ++S  + +        L + + Q SD+G Y
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSP-VSSFSNGLQVLSGGRILALTSAQISDTGRY 2081

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T        C+      AV +  E              +QR+ + R+ +    +  +   
Sbjct: 2082 T--------CV------AVNAAGE--------------KQRDIDLRVYVPPNIMGEE--- 2110

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              Q+  V   +     C+    P P +TW  +   +       I  N S    L I +  
Sbjct: 2111 --QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---VLKIEDAQ 2165

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            + D+G  TC A N +G+T     +N+     +      +  + L V EG  + L   + G
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGS---DELTQLTVIEGNLISLLCESSG 2222

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             P P + W+K G P++ +   R+    G   L I  A+ SDAA Y C A NVAG+
Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 3503

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 3560

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 3561 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
            P  V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 1460 PNEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 1510

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 1567

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 1568 ECETRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 1625

Query: 571  S 571
            +
Sbjct: 1626 T 1626



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/281 (24%), Positives = 114/281 (40%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 1851 NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 1901

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 1902 NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1938

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+ ++R +    +   L   +    + I +  +SD+G+  CVA N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQIIDIESAQISDAGIYKCVAIN 1995

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1996 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +  A+ SD   Y C A N AG
Sbjct: 2051 P-VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 2090



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 13/177 (7%)

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            V  D  V    + + +C   G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 1553 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 1609

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
            +SDS   TC   N +G       ++V      V P      +T LN  V     + L  +
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECK 1664

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P+P +TW KDGVP+  N  +RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 12/168 (7%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 4236

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G
Sbjct: 4292 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 4315

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K    + V+E          PP F     +  +    G
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE----------PPVFKGDYPSNWIEPLGG 4365

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 4366 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 4421

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 4422 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 4464

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 4465 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 4520



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 52/187 (27%), Positives = 81/187 (43%), Gaps = 11/187 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+   + +++  T G      C  TG P P++ W +ND  I   + +++    + +  L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM----TSDGTLF 667

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V+ 
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVME 722

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N AG 
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGR 780

Query: 572 TATRARL 578
              +  L
Sbjct: 781 ATGKITL 787



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
            L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 1307 LTGREPGISILEDGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 1363

Query: 398  CQ---DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
             +   +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GKILKLFR 1420

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
             T  D+G  +C A N +G +     ++V+    ++   F    S +  R+   V L  + 
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD---VALECQV 1477

Query: 515  VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 1533

Query: 572  TATRARL 578
             A   +L
Sbjct: 1534 QAKDIKL 1540



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 909

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 966

Query: 570 GS 571
           G+
Sbjct: 967 GT 968



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 4426 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 4480

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 4481 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 4521



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG +    C  +G P P + W      +  D   ++ +  SG   L I+    SD+ +
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL-SGGRQLQISIAEKSDAAL 2266

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             +CVA N +G    +  L V  +  +         + + V  G+ + L     G P P +
Sbjct: 2267 YSCVASNVAGTAKKEYNLQVYIRPTIT--NSGSHPTEIIVTRGKSISLECEVQGIPPPTV 2324

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            TW KDG P+I    + I  +G    L +     SD   Y C A NVAG T
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAVNVAGMT 2372



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 4314

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G   F   +  +  ++   P F   + +  +   G   +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG---FVKAIGFVYVKE--PPVFKGDYPSNWIEPLGGNAIL 4369

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/345 (22%), Positives = 130/345 (37%), Gaps = 37/345 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I +V + D   +  +A +  GT +      V E          PP       NV VT 
Sbjct: 484  LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE----------PPPVIQVPNNVTVTP 533

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L   +      ++ W +N + V+     +I       +L +      D+G+Y C+
Sbjct: 534  GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCM 592

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              +  G +       V                  PP++    K++    G  +   C   
Sbjct: 593  VSSEGGSSAASVFLTVQ----------------EPPKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P P + W   D  I  S  ++M  T+D  TL I  A P+D G Y C+A NSAG     
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRM--TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            + L+  +  +      +    +++V  G     + + +    P ++W +    +   P  
Sbjct: 694  STLRYIEAPK-----LMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPST 746

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +I +    +L I  T + D G +TC A   AG+      L V S
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D  V     T   C     P   +TWF +   +  + N +IL    G   L I N    
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQED 2639

Query: 459  DSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            ++G  +CVA N++GE      + V     I K  +  P    +   + ++    + L   
Sbjct: 2640 NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE 2697

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   P+  ++W KDG P+  +  + I  +G   TL I  A+ SD   Y C A N+AG
Sbjct: 2698 AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAG 2752



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 3762 ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 3876

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 3877 TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 3932 KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 74/294 (25%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            +G+         G P P + W ++GQ L   + H  ++TH    L++   +  DSG YT 
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG-MVLQLLKAETEDSGKYTC 3506

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            +A N  G +     L V  P           +I  +++ E     EIS     P     C
Sbjct: 3507 IASNEAGEVSKHFILKVLEP----------PHINGSEEHE-----EISVIVNNP-LELTC 3550

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                +   KMT       GRP P+        Q++            G   L I+   + 
Sbjct: 3551 IASGIPAPKMTWMK---DGRPLPQTD------QVQ---------TLGGGEVLRISTAQVE 3592

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G  TC+A + +G+   +  + V     +         + L  R+   V L  ++   P
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ---VTLECKSDAVP 3649

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P ITW ++G  +   P +RI +  G   L I  A   D A Y C A N+AG T
Sbjct: 3650 PPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGKT 3701



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L I  V   D+G  TC+
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQIAFVQPGDAGHYTCM 4149

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 4150 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4204

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 4205 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 61/277 (22%), Positives = 112/277 (40%), Gaps = 28/277 (10%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            ++   V    P  + +++NG  +  D   + L+E  +  L I +    D G YEC+A++S
Sbjct: 448  QIPCSVDSLLPFTLSFVRNGVTLGVD---QYLKESASVNLDIAKVTLSDEGFYECIAVSS 504

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG  R      VS                 PP +I+   +  V  G+    +C I+    
Sbjct: 505  AGTGRAQTFFDVS----------------EPPPVIQVPNNVTVTPGERAVLTCLIISAVD 548

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
              + W + D+ ++ ++  ++ RT    +L +      D G+Y C+  +  G    +  L 
Sbjct: 549  YNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            V +P +   +P     ++     G         T   KP I W      I  +  ++M  
Sbjct: 608  VQEPPKVTVMP-----KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            +G    L I N   +D G + C A+ +AG  + ++ L
Sbjct: 663  DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 12/201 (5%)

Query: 402  DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
            +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 955

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 956  GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 1010

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             + W K G  +I     +  + G   +L +      ++  Y CTA N AG    + +L  
Sbjct: 1011 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068

Query: 581  XXXXXXXXXQKRLHLPRPTKV 601
                     Q+ L   +P ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEI 1089



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 12/188 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++V  +  VT G+     C +       +TW  NDR +R        +    N +L 
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVL 510
           + +V  +D+G   C+  ++ G +A    L V E  +V V PK        +   G  V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK------NQSFTGGSEVSI 631

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P+I W  + + I+ +   R+ +DG   TL I  A   DA  Y C A N AG
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688

Query: 571 STATRARL 578
           +    + L
Sbjct: 689 TDKQNSTL 696



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N+ G+++    L   
Sbjct: 2996 LSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   EC    V  P   I WY NG+ +  ST ++ 
Sbjct: 3054 VPPSIKDHDSESLSVVNV---REGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEI 3108

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 3109 LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 104/477 (21%), Positives = 174/477 (36%), Gaps = 55/477 (11%)

Query: 99   PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            P P ++W +   PL   +K  +      G   L I +    D G YTC A N+ GE    
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLIL----PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860

Query: 159  ----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                V + P                 + S  +E  + G+        +  Q +   +   
Sbjct: 2861 YDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--H 2918

Query: 215  HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
            H    + ++       + ++     + +   G +    +  +      V P  I  K  N
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-----VPPSVIGPKSEN 2973

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
              +          ++SG P P ++W KN Q  I  N + +I      TL++   + SD G
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQP-IKLNTNTLIVPGGR-TLQIIRAKVSDGG 3031

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERIEISEKALAPQ 393
             YT +A N  G       L V  P    ++D  S+ ++    RE T   +E    A+ P 
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSLECESNAVPPP 3089

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
             +   ++     G+M      +T   + E+   + D Q+   +  K  V+++G +     
Sbjct: 3090 VITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVSDTGQYVCRAI 3133

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV               +G       LNV     +  P+      T++     PV L   
Sbjct: 3134 NV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS----NPVTLTCD 3174

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C A N+ G
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 4432 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 4482

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 4483 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 4531



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C+  G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 1718

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  I
Sbjct: 1719 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 1776 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 1812



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 1238

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
             TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 1239 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 1296

Query: 521  RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W  +G  +    P + I  DG  + L I      D   Y C A N AG+T  +  L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 14/157 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA----EISVK 3137
            I WF +G  +E++  IR +   G   L+IL  +  ++G YSC ATN+ G+     E+ V 
Sbjct: 2607 ITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVY 2664

Query: 3138 L-ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +   ++K     P  +   + ++ +K   +   EC    +  P   + WY +GQP++   
Sbjct: 2665 IPPIINKGDLWGPGLSP--KEVK-IKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDD 2719

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +   ++ G   L I   Q  D+G Y C A N  GED
Sbjct: 2720 HVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGED 2754



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 62/288 (21%), Positives = 104/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 4132

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 4133 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4192

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 4193 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 4250

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 4251 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 4303

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +   G++ V+ P
Sbjct: 4304 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 3515

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 3516 SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3569

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 3570 PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 3608



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +  S  IR + A G V+  I+  + +D   Y+C A+N+ G    
Sbjct: 3367 TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYTCVASNRAGVDNK 3424

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L+            T  I  ++    G S    C       P M   W  +GQP+  
Sbjct: 3425 HYNLQVFAPPNMDNSMGTEEITVLK----GSSTSMACITDGTPAPSM--AWLRDGQPLGL 3478

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + TVS  G +VL +   +  DSG+Y C A N+ GE
Sbjct: 3479 DAHL-TVSTHG-MVLQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 17/203 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +L+IL T+ TD G Y C A N  G A+   ++ +       G K    T + N       
Sbjct: 2927 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN------- 2979

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                  C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C
Sbjct: 2980 NFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTC 3035

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----E 3280
             A N+ GE   + ++  Y    +     +  S+  +RE  S+    +     P      +
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3095

Query: 3281 PPKFITQIQDVTKLVEGQSAHFE 3303
              + IT+   V  L +GQ  H +
Sbjct: 3096 NGRMITESTHVEILADGQMLHIK 3118



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 64/257 (24%), Positives = 98/257 (38%), Gaps = 22/257 (8%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P + W +K +P++  +   +R    +G   L I      D   Y+C A N  G A 
Sbjct: 2222 GIPPPNLIWKKKGSPVLTDSMGRVRI--LSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279

Query: 157  ----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
                  VYI+P                R  S ++E +  G    T    +    +    G
Sbjct: 2280 KEYNLQVYIRPT-ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG 2338

Query: 213  TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES-DVQISTEIDRSLGPVSPPKIA-- 269
             +            E  +L+  +   S T RYV  + +V   T+    L   +PP I   
Sbjct: 2339 VEILD---------EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389

Query: 270  -QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             + P N  + E        + SG P P +TWFK+G  +  SN   I++      LR+  T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQT 2447

Query: 329  QKSDSGHYTLLAENPNG 345
               D+G YT +  N  G
Sbjct: 2448 TMEDAGQYTCVVRNAAG 2464



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 3728 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 3784

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 3785 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 3883



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           + ES +  L I  VTLSD G   C+A + +G    Q   +V E      P  ++  + + 
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE-----PPPVIQVPNNVT 530

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V  GE  VL    +      +TWQ++   +      RI T    S L++   K +DA  Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEY 589

Query: 562 QCTAQNVAGSTA 573
            C   +  GS+A
Sbjct: 590 HCMVSSEGGSSA 601



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 260  LGPVSPPKIAQKP--RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            L  + PP I  +    + K++E        +++GNP P +TW K+GQ L     H II+ 
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS- 2530

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L++ N Q   +G YT LA +P G
Sbjct: 2531 -GGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 86/218 (39%), Gaps = 35/218 (16%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            ++ IK       E     I  ++L   W KDG+P+++   +    N G+  L IK   + 
Sbjct: 2683 EVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQIS 2738

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEV 1037
            D G YTC A N  G+     ++ I          Q P   +K+  + +     +  E + 
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI----------QVPPSFQKLWEIGNMLDTGRNGEAKD 2788

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD 1097
             I   P                S + E    P   LT    WY +G  +TS++++     
Sbjct: 2789 VIINNP---------------ISLYCETNAAPPPTLT----WYKDGHPLTSSDKVLILP- 2828

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G   L I   + ED+G YT VA N AGE  L   + V
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 74/293 (25%), Positives = 118/293 (40%), Gaps = 46/293 (15%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   + WY +G+ L+      + ++ G  TL + +    D+G YTC A N  GE      
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGEDELDFD 2759

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            V            Q P   + L +I N+ D             TGR  E     KD++ I
Sbjct: 2760 V----------NIQVPPSFQKLWEIGNMLD-------------TGRNGEA----KDVI-I 2791

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +     + E +  P       + W+ +G  + +S ++  +   G  VL+I   K  D+G 
Sbjct: 2792 NNPISLYCETNAAPPP----TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGR 2845

Query: 3121 YSCRATNKWGQ--AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            Y+C A N+ G+   +  V++      KG        +  +      +SA  EC  +    
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLV----NKSALIEC--LSSGS 2899

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P  +  W  +GQP+      K +S+    +L I  TQ  D G YVC A N  G
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAG 2950



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 66/168 (39%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 4012 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4069

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 4070 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 4121

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L IA+ Q  D+G Y C A N  G   T   +  +
Sbjct: 4122 SIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 3236 YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 3287

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 3288 ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 4431

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG P+T+S ++  I   G V L I   + EDAG YT  AVN+ GE      
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVL-ILPGGRV-LQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862

Query: 860  IRVAARSTVT-ADLGIPEQ 877
            +RV     +  A+  +PE+
Sbjct: 2863 VRVLVPPIIKGANSDLPEE 2881



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   N   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 4404

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 4405 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 1311

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 1312 PGISILEDG-TLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            ++   EC++  +  P   V W  +G PL+ K +   I D G++ +    ++  D+G Y+C
Sbjct: 2308 KSISLECEVQGIPPPT--VTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSDTGRYVC 2363

Query: 4049 RATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
             A N+ GM + K  +     P I+ + + P+++  +EK
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 4194 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 4250 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 4300

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V     I        P      P N  
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWI 4360

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 4361 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 4417

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 2104 PNIMGEEQN 2112



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 18/164 (10%)

Query: 3079 SMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            S  + W+ +G+ +++   +  + A G   L+I   + +D+G Y+C A+N  G+ E+   +
Sbjct: 2703 SASLSWYKDGQPLKSDDHVN-IAANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV--PVD-------DPDMKIEWYHNG 3189
                    QK      I N+  L  G++   +  ++  P+         P   + WY +G
Sbjct: 2761 NIQVPPSFQK---LWEIGNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG 2815

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+  S ++  +   G  VL I   +  D+G Y C A N+ GED
Sbjct: 2816 HPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 3255 DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 3312

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            D+G YTC ATN  GE      L V     +     +    EK+  L DTS
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTI---RGNKDEAEKLMTLVDTS 3359



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  +  N     GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 4402

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  N   I  SHR R   + G + ++    K  D+G Y C A+N  G  + 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQ 692

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            +  L  ++  K         +Q+   +  G     EC    +  P +K  W+     +R 
Sbjct: 693  NSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGIPPPQVK--WFKGDLELRP 744

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLE 3250
            ST +  + D    +L I  TQ+ D+G+Y C A N+ G    + T++  G   V+++
Sbjct: 745  STFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD-VGSPPVFIQ 797



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 1170 PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 1268

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 1269 ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 1308

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 1309 GREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 1368 TNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 4078 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 4131

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 15/197 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP    V  ++  ++ G+ A     +I   D ++   W  N + +  +   R +  
Sbjct: 515  DVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLT--WQRNDRDVRLAEPAR-IRT 570

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               + LE+   K  D+G Y C  +++ G +  SV L        Q+P   T +   +   
Sbjct: 571  LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV------QEPPKVTVMPKNQSFT 624

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G      C+      P  KI W  N   +  S R +  SD    + + A     D+G Y
Sbjct: 625  GGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAA---PKDAGIY 679

Query: 3223 VCRAYNKYGEDFTRATI 3239
             C A N  G D   +T+
Sbjct: 680  GCLASNSAGTDKQNSTL 696



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PP    +P   +   G      C  TG+PKP++ W +N   IV   RY++T DG
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 4489 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 4544

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 4545 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGK 875



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 756  LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 809

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 810  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 870  ENQFGKIQSETTVTVTG 886



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 789  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 849  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 1371 SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDA 1426

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST-QNEAG--LEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +   NE    L +   LE + K      + 
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 1486

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 1487 WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C        A+T    G  I+ S +++Y++      
Sbjct: 1546 PSIKGGNVTTDI-SVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 1604

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 1605 IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++ +    + G   L +      D G Y C A +  GE
Sbjct: 1664 KAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV      +L++      D+G YSC+A N  G ++  
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVN--NGKILKLFRATPEDAGRYSCKAINIAGTSQKY 1443

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +           T+  N   +   +    EC V     PD  I W+ +G+P+   
Sbjct: 1444 FNIDVL----VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLG 1497

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 1498 DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +    G  I  E  ++ +  PT  + W+K+G  +   ++   I   G+I L + ++++ D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSD 2357

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
            +G Y C AV+  G+ + K  L V    +I    + PE +  +++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 35/210 (16%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++++  N     E     +  P   + W ++G P+++ + +    + G+  L +K    
Sbjct: 2682 KEVKIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQI 2737

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G YTC A N  GE      + +Q   S Q        L +I  + D+ R    +DV 
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ-------KLWEIGNMLDTGRNGEAKDVI 2790

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +            N P  L         C     P P +   WY +G  L S  +     
Sbjct: 2791 I------------NNPISL--------YCETNAAPPPTL--TWYKDGHPLTSSDKVLILP 2828

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
              G   L I     ED+G YTC A+N  G+
Sbjct: 2829 --GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 57/266 (21%), Positives = 102/266 (38%), Gaps = 11/266 (4%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            L GNP P   W +  A L++    ++R      D SL I+++   D GEYTC A N  G 
Sbjct: 914  LAGNPIPERRWIKNSAMLLQNPYITVR-----SDGSLHIERVQLQDGGEYTCVASNVAGT 968

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               +  +                    +  T+  KA G    +   S++ + ++ ++   
Sbjct: 969  NNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF 1028

Query: 215  HSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
             +  D    V +       E     + T  Y  +  VQ++  +   +          KP 
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYA-KRKVQLTVYVRPRVFGDQRGLSQDKPV 1087

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSD 332
               +  G +     ++   P P +TW K  Q +   S +H  + + +   +++  T+ SD
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSD 1144

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESP 358
            SG Y  +A N  G +  +  L V  P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVP 1170



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 3652 VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 3710 NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 3759

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 3760 YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 3801



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 3952

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 3996



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +G  +  S+ +R +   G  +L ++ T   D+G Y+C   N  G+      L  +
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P        +E +K  +      T     +P  +I W+ +GQP++       +
Sbjct: 2476 ------VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII 2529

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S   F  L I   Q   +G Y C A +  G      ++N +
Sbjct: 2530 SGGRF--LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2568



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  EC+   V      + W+KNG+ +T       + D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHL 3145



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 3299

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+  L 
Sbjct: 3300 NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTLV 3356

Query: 1960 DDS 1962
            D S
Sbjct: 3357 DTS 3359



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 4252 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 4306

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 4307 VN--GHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     S+ +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 4400

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     ED+G YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1385 CQATNQLGEAVTSCALRVIAKKDLILE 1411
            C ATN+ G    S +L + +   + LE
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 4364 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 4419 CVATNEAGVVERSMSLTLQS 4438



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    + KN  F  G          G P P ++WT     +V  ++Y M     T D +
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM-----TSDGT 665

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L IK   P D G Y C A N  G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAG 688



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I +  G     E  ++ I   T  V W+KDG P+  +  +    + G++ L +K++ V 
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI-LQLKNIHVS 2356

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            D G Y C A N  G      +L++     II   + P  +  ++
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G  +L I  V   DAGHYTC A N  G ++TS  LT+
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 1252 TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 1305

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 1306 ELTGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPII 1392



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 3676

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++ N    D+ +YT +A N  G       L V  P
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 3712



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 4429 ERSMSLTLQSPPIITLE 4445



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 20/170 (11%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDI---------IDESVTIKPRFVTRPKSIE 1454
            AK   IL+  H   L+ I ++ DT RY    +          D SV   P  +   +S E
Sbjct: 2336 AKGVEILDEGHILQLKNI-HVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE 2394

Query: 1455 N--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            N  V+E   V   C+   +   +  + WFK+G PV++ +  R +   G   L ++    E
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPS--ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTME 2450

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            D+G YTC   N  G +     L+      IV     E  LE ++V E +S
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLVPPHIV----GENTLEDVKVKEKQS 2496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632  RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 3429 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 3485

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
              G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 3486 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 3518

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 3519 FILKVLEPPHINGSEEHE 3536



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 3605 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 3655

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 3656 LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 3700



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 3766

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 3767 F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 12/174 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C ATN  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 1188

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 1189 DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 1244

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P
Sbjct: 1245 NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKP 1296



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 1579 ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 1635

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +  I+  
Sbjct: 1636 YVPPMIEGNLATPLN--KQVVIAHSLTLECKA--AGNPSPILTWLKDGVPVKANDNIRI- 1690

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 1691 -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG PV  S+ +      G   L +   T+ DAG YTC   NA G+      L+++
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 1003 TKKDIIAES 1011
                I+ E+
Sbjct: 2476 VPPHIVGEN 2484



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 3257 SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++  L D S
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTLVDTS 3359



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 1216

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 1217 HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 1256



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T   ++ S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 1496

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 1497 GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I V  G  +  +C V+ +  PT  + W  +G P      V  L++ G I L +  I+  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GHI-LQLKNIHVSD 2357

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
             G Y C A N  G       ++  A   I+   + P+ +S
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS 2397



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 3261 GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 3319 CVATNPAG 3326



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 4131

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 4132 --SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P+ +    N     G+ V + C     G    ++ W  N   I   HR+R   +
Sbjct: 606  LTVQEPPKVTVMPKNQSFTGGSEVSIMC--SATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI-AKKDLILESQHPSGLEKIQY 1423
                 L + +  P+D+G+Y C A+N  G    +  LR I A K ++++S+    L  I  
Sbjct: 664  G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITV 720

Query: 1424 LE 1425
            +E
Sbjct: 721  ME 722



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 714 ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 769

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 770 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 826

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 881

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 938

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAG 967



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 1351 YNLKVHVPPVIKDKEQ-------VTNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 1400

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 1401 VTESSTIQTVNN--GKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+  IR + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 1725 YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLIDE 1777

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 1778 RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 1813



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEK 2092

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 2093 QRDIDLRV 2100



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 633  VYPPPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V+ PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTN--TLIVP 3015

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            G  +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   V  EC  E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 3071 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 3127 QYVCRAINVAGRD 3139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LEC    +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 4433 SLTLQS 4438



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 860  IRVAARSTVTADLGIPEQRRYI 881
            + V     +  +L  P  ++ +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVV 1654



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ + + +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 2003

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 2004 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 2053

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +   Q  D+G Y C A N  GE
Sbjct: 2054 SFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVNAAGE 2091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G+ +  EC+++ +      V W K+G P+ I  +   I D G++ L + ++   D+G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSDTG 2359

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             Y C AVN+ G  +    L+  +   I+    N    E I V+E  S
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSII---GNHRSPENISVVEKNS 2403



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G++   E ++  +  PT  V W KDG P+  +  +  I + G++ L + ++   D G Y 
Sbjct: 2307 GKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGV-EILDEGHI-LQLKNIHVSDTGRYV 2362

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
              AVN  G       + V A  ++  +   PE    +EK
Sbjct: 2363 CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   EC     P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 3073 EGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 3302 STLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)

Query: 3047 PPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP  +   K+ ++ + +      EA  +P  D    I W  +G+ I  S R R V + G 
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPD----ITWHKDGRAIVESIRQR-VLSSGS 4132

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LK 3162
              L+I   +  D+G Y+C A N  G +  S KL     +    PR    I++ EG   + 
Sbjct: 4133 --LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL-----TVHVPPR----IRSTEGHYTVN 4181

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +   A   C    +  P   I W  +   + +     T   +G ++L+    +  DSG Y
Sbjct: 4182 ENSQAILPCVADGIPTP--AINWKKDNVLLANLLGKYTAEPYGELILENVVLE--DSGFY 4237

Query: 3223 VCRAYNKYGED 3233
             C A N  GED
Sbjct: 4238 TCVANNAAGED 4248



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 788  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 900

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 901  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 956

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 957  EYTCVASNVAG 967



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 1351 YNLKVHVPP 1359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 84/375 (22%), Positives = 143/375 (38%), Gaps = 32/375 (8%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            +NI V E   V   C  E  G P   I WF +G P +  + V  L+  G   L +     
Sbjct: 2394 ENISVVEKNSVSLTC--EASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTM 2449

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+YTC   N  G       ++      IV E+ L      EK        ++  P  
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E       + + + ++H +    G RF  ++   + P      Y      P+GH+ R+  
Sbjct: 2510 EITWHKDGQPLQEDEAHHI--ISGGRF-LQITNVQVP--HTGRYTCLASSPAGHKSRSFS 2564

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVND------FGEDFTKATISCKKLPDIILQNQVPR- 3935
               FVS  I  V ++ + E +   +N           +  ATI+  K    +  N+  R 
Sbjct: 2565 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI 2624

Query: 3936 --GMKRSEALTQMEATIKKYTSEVYLTEDDL---YDVDKKQPP------RFVTQIQSQTS 3984
              G +  + L   E    +Y+        ++   Y+V    PP       +   +  +  
Sbjct: 2625 LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEV 2684

Query: 3985 LVEMETT-KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
             +++  T   EC+   +  P+  + W+ +G+PL   +    I   G+  +        D+
Sbjct: 2685 KIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVN-IAANGH-TLQIKEAQISDT 2740

Query: 4044 GEYLCRATNLYGMDE 4058
            G Y C A+N+ G DE
Sbjct: 2741 GRYTCVASNIAGEDE 2755



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 4429 ERSMSLTLQS 4438



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 87/402 (21%), Positives = 156/402 (38%), Gaps = 41/402 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 791  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 966

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 967  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 1023

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDQRGLS 1082

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 1137

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +    DSG+Y C A N+ G    + +L       I R  ++
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 1544 IPPSIKGGNVTTDI----SVLINSLIKLECETRGLPMP--AITWYKDGQPIMSSSQALYI 1597

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 1598 -DKG-QYLHIPRAQVSDSATYTCHVANVAG 1625



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 2063

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 2064 GGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V  GK+   EC+V+ +  P   + +  +G  L  A    I  D G++ L +++    D G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTG 2359

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             Y   A+N  G       ++V A  SII   + PE +  + +   +   +   IP P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 3261 GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDT--QNEQAIEQIQLLEDAA 1295
              A N  G        R+   +  VT T   N+   E++  L D +
Sbjct: 3319 CVATNPAGEED-----RIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 3359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S      G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 4399

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL+L+S   +   +   +  S        V + V + P+ +T +      + G      C
Sbjct: 575  SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMC 633

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P  ++ W  N   +   HRYR ++D     L I     +D+G Y C A N+ G
Sbjct: 634  SATGYPKP--KIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 1927 QAVSSIRLN-VQSKESIIRDSQHESALEKIQYLE 1959
                +  L  +++ + ++  S+   AL  I  +E
Sbjct: 689  TDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 897  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 952

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 953  QDGGEYTCVASNVAG 967



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 1224

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
             +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 1225 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 1907

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY + + +
Sbjct: 1908 QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNRLL 1961

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1962 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1998



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +   + +D+G Y+C A N  G+ +  + L   
Sbjct: 2043 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVY 2101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 2102 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 2152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S+    VL I   Q  D+G Y C A N  G+      +N +
Sbjct: 2153 SE-NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 54/211 (25%), Positives = 82/211 (38%), Gaps = 34/211 (16%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            S K V+IK       E     +  A+L   WY + +PLKS        N G   L I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASLS--WYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSA 1702
               D+G YTC         V S IA    +    +  Q   +  +L ++ +     R+  
Sbjct: 2736 QISDTGRYTC---------VASNIA-GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
              +VI   P+           E  AA           P   + W ++G P+ +S+++  +
Sbjct: 2786 AKDVIINNPISLY-------CETNAA-----------PPPTLTWYKDGHPLTSSDKVLIL 2827

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G   L +     ED+G YTC A+NE GE
Sbjct: 2828 P--GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633  VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 3052 VYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTH-VEI 3108

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
               G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 3109 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 3154



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 3126

Query: 842  SYTVRAVNKLG 852
             Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             NL +     I          EK+  L D S
Sbjct: 3332 FNLNVYVTPTIRGNKDE---AEKLMTLVDTS 3359



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS+ I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 4403

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 4404 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 4461

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 4462 QATGEPQPTIT 4472



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 18/270 (6%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 1102 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATNIAG 1157

Query: 154  EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
                +V +                        +   A GT       S+    +   +G 
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 1216

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
             H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 1217 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 1269

Query: 272  PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
            P N+  QE    Q   F     G P+P + W  NG+ L    +  I    + T L + + 
Sbjct: 1270 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEDGTLLVIASV 1328

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               D+G Y  +A N  G       L V  P
Sbjct: 1329 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 22/283 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 1225

Query: 131  LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
            L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 188  H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                A GT        + T K  + NG + +  +       +  LL   S        Y+
Sbjct: 1286 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337

Query: 246  GESDVQI-STEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
              +  +  +TE   +L    PP I  K +  N  +          ++ G P P + W+K+
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 1398 NVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ I+     + +     +V  I   + +++G Y C A N  G    
Sbjct: 1759 TGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKK 1816

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 1817 EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 1865

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 1866 PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 724  AVLHVTPRATIE 735
              LHV    ++E
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQIS--DTGRYTCVAVNAAGEKQR 2094

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 2095 DIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P+++I++   S   EC +  +   +  V W  +G PL+    V+ +++ G  IL++  ++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GH-ILQLKNIH 2354

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
              D G Y C A N  G       L V     II   + P +
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            +L++     +D+G Y C A N  G  +    L      S     R   +I  +E  K+  
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE--KNSV 2404

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   E + +P+      I W+ +G P+  S  ++ +S  G  +L +  T   D+G+Y C 
Sbjct: 2405 SLTCEASGIPLPS----ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCV 2458

Query: 3226 AYNKYGED 3233
              N  GE+
Sbjct: 2459 VRNAAGEE 2466



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 34/215 (15%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+    +   EC  E Y  P+  + WY +G+ L+S      + + G   L I      D+
Sbjct: 2685 KIKVNNTLTLEC--EAYAIPSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDT 2740

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G YTC A N  G+      +N+Q   S          L +I  + D  R   A       
Sbjct: 2741 GRYTCVASNIAGEDELDFDVNIQVPPSF-------QKLWEIGNMLDTGRNGEA------- 2786

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
                         +V   +P+ L         PT+   WY +G P+      K     G 
Sbjct: 2787 ------------KDVIINNPISLYCETNAAPPPTL--TWYKDGHPLTSSD--KVLILPGG 2830

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              L I  A  ED G Y C A N  GE      V+V
Sbjct: 2831 RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 3122

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 3123 SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 3170

Query: 3548 LTPEAESGNPP 3558
            LT +A +G PP
Sbjct: 3171 LTCDA-TGIPP 3180



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 785  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 843

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 844  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 1006 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 1063

Query: 724  AVL--HVTPR 731
              L  +V PR
Sbjct: 1064 VQLTVYVRPR 1073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTV-NNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 860  IRVAARSTV 868
            I V    T+
Sbjct: 1446 IDVLVPPTI 1454



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+  +   +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 1510

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1952 ITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 2010 VAPSISGSN 2018



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            +++  + V   P      + PT++  + G+S   EC ++  P P   V W  +G  L   
Sbjct: 2279 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKA 2336

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                  ++     L +  ++  D+G Y C A+N  G       L+V +  SII    H S
Sbjct: 2337 KGVEILDEGHI--LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII--GNHRS 2392

Query: 1951 ALEKIQYLEDDS 1962
              E I  +E +S
Sbjct: 2393 P-ENISVVEKNS 2403



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +C    V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 3124

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 3125 TGQYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 3126

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626  PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 3661

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 3662 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 3529 EGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS 3588
            EG  + IA     +G   T    +E   PP     P+++ ++    A   C +I   D +
Sbjct: 494  EGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550

Query: 3589 MRVEWFHNGKP--LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            +   W  N +   L   +R++T+ +     LE+  V   DAG Y C  ++  G +  S  
Sbjct: 551  LT--WQRNDRDVRLAEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVF 605

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTE 3670
            L V+    + + P+  S F  G+E
Sbjct: 606  LTVQEPPKVTVMPKNQS-FTGGSE 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PPK     K+ +      V   C       PK +I W  N   +   HRYR   D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGY--PKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              +L I     +D+G Y C A N  G D   +T+   + P +++
Sbjct: 664  -GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 916 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 972

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 973 TSVVVHVLP--TIQHGQQILSTIEGI 996



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P+++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 1446 IDVLVPPTIIG-----TNFPNEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 1496

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 1497 GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 1405 KKDLILESQ-HPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            +K +I ++Q   +GL +         +KK    + +V + P   +   S   V++ + V 
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVA 1845

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
             +C    +   N  + W K+ QPV        I   G V L I   + ED+G YTC A N
Sbjct: 1846 LQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902

Query: 1524 LVGTDEVSCRL 1534
              G  +   +L
Sbjct: 1903 AAGETQQHIQL 1913



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S P   + W+KDG P+ ++  I  +   G  +L I++ + ++AG Y+  A N+ GE I  
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658

Query: 858  ASIRV 862
              ++V
Sbjct: 2659 YEVKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+G  L +   ++     G  TL I + + D++G Y+C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2732 IKI 2734
            +K+
Sbjct: 2661 VKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +C    V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 860  IRVAARSTV 868
            + V    T+
Sbjct: 3334 LNVYVTPTI 3342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 3829 GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 3886

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 3887 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 3945

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 3946 ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 3998

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 4056

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQVP 4078



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 4126

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 4127 VLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 791  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 850  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 994  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 1003 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 1058

Query: 154  EA----ICSVYIQP 163
             A      +VY++P
Sbjct: 1059 YAKRKVQLTVYVRP 1072



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/179 (21%), Positives = 72/179 (40%), Gaps = 7/179 (3%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W   G  +      R     G   L+I   + +D+  YSC A+N  G A+    L+    
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY-- 2287

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             +       +H   I  +  G+S   EC V  +  P   + W  +G P+  +  ++ + D
Sbjct: 2288 IRPTITNSGSHPTEII-VTRGKSISLECEVQGIPPP--TVTWMKDGHPLIKAKGVE-ILD 2343

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
             G  +L +      D+G YVC A N  G    +  ++ +    +      P++++ + +
Sbjct: 2344 EGH-ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E  + P  TI WF +G  + +    R     G   L IL    +++G Y C ATN+ GE 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 2194 VNTCTLKV 2201
            +    +KV
Sbjct: 2656 IKHYEVKV 2663



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIH--FETRIE----PVGDPTMKIEWLKNGQSI 679
            P GEEDR++    ++ P       E  K+    +T I       G P  +I WLKNG  +
Sbjct: 3324 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 3383

Query: 680  EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
              SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 3384 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 3421



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 3728 KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 3784 MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 3795

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 3796 IDLQVHVPP 3804



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 4151 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 4204

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 4205 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 1253 EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 1304

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 1305 RELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 1346



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 1259 QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 1312

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 1313 GISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 1354



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 653  KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            K+  ETR    G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC 
Sbjct: 1566 KLECETR----GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCH 1619

Query: 713  AVSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
              +  G AE    + V     IE     P   Q +
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 1654



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284  QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
            + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 1623

Query: 344  NGCIVTSGYLAVESP 358
             G    S ++ V  P
Sbjct: 1624 AGTAEKSFHVDVYVP 1638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+ + +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 2003

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 2004 YSLQVHVAP 2012



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKDG P+     ++   N     L I+   V D G YTC A N  G+   + N+ I
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ WY +G+ + S + +    + G+  L I   +  D+G YT VA N AGE +L   + +
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            +   S       + L+E          +  M       ++K V +   +NP        I
Sbjct: 2763 QVPPSF------QKLWE----------IGNMLDTGRNGEAKDVII---NNP--------I 2795

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C       PT+   W+ +G  +T  S  K     G   L I  A   D G YT  AV
Sbjct: 2796 SLYCETNAAPPPTL--TWYKDGHPLT--SSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851

Query: 1256 NHLGSAHTSAIVRVI 1270
            N  G       VRV+
Sbjct: 2852 NEAGEDSLQYDVRVL 2866



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 3253 PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 3309 ALTSDTGKYTCVATNPAGE 3327



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 3469 WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 3526

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 3527 PHINGSEEH 3535



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 3523 VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 3580

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 3581 GEVLRISTAQVEDTGRYTCLASSPAGD 3607



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 3767

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 4197 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254

Query: 1134 TV 1135
            TV
Sbjct: 4255 TV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 4268 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 4321

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G     G
Sbjct: 4322 DSGTYVCTAENSVGFVKAIG 4341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 4451 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 4506

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 4507 FECVARNLMG 4516



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  KI W  N+  +    RY+ T D +   L I +   +D+GIY C A+NS G+   + +
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 2863 LR 2864
            LR
Sbjct: 696  LR 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 994  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 1106

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 1107 PPPIITWAK 1115



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 265  PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP I     P    +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 1509

Query: 323  LRVRNTQKSDSGHYTLLAENPNG 345
            L ++N +++D G Y     N  G
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 7/149 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            SH   I+   G +I  EC V+    PT  + W  +  PL      +   D  ++ L + +
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKN 2352

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
             +  D+G Y C A N  G       L      +I  + + P+    +  VE+   +   +
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE---NISVVEKNSVSLTCE 2409

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEG 2926
                 +P   + K  W + ++   +++ G
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSG 2438



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   + W+ +G P++     +     G   L IL A  ++ G Y C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2067 VKV 2069
            VKV
Sbjct: 2661 VKV 2663



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 3124

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 3242 QVPPSVAGAEI 3252



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 3439 SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 3494

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 3535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 4100 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSS 4157

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 4158 STSTKLTVHVPPR--IRSTEGH 4177



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 4194 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 4251

Query: 997  ANLTI 1001
             +LT+
Sbjct: 4252 VSLTV 4256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 6/142 (4%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
            Q  + +    L I++    DEG Y+C+A +SAG         V++P     +P      +
Sbjct: 474  QYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVP-----NN 528

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V  G+ A     I S +   + W R    +    +   I    N  L + +    D G
Sbjct: 529  VTVTPGERAVLTCLIISAVDYNLTWQRNDRDV-RLAEPARIRTLANLSLELKSVKFNDAG 587

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C  ++  G    S  L V+
Sbjct: 588  EYHCMVSSEGGSSAASVFLTVQ 609



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK ++ W  N + I  S+R     D     L +K   P+D+G Y C A N  G    +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 1798 STL-FVQSKASLQLESQHESALQKIQQLE 1825
            STL ++++   + ++S+   AL  I  +E
Sbjct: 694  STLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 775  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449

Query: 1003 TKKDII 1008
                II
Sbjct: 1450 VPPTII 1455



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 3833 ITQIKSHTVE----ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            IT   SH  E      + +  EC V+    P   + W ++G  L        + D G + 
Sbjct: 2292 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI- 2347

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGM 3937
            L +  ++  D+G Y+C AVN  G    K  +S    P II  ++ P  +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2396



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            P   + WF +G  L      R     G   L IL   E+N+G Y CVATN+ G
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            DV    P+   C       PT+   W+ +G P  +  +V  L   G   L I      DA
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDA 2843

Query: 3766 GEYTCRATNKWG 3777
            G YTC A N+ G
Sbjct: 2844 GRYTCVAVNEAG 2855



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL TL D+ +
Sbjct: 3334 L------NVYVTPTI-RGNKDEAEKLMTLVDTSI 3360



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 3581

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 3685

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 3686 -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3744

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 3745 TWRKDGAVLAGNHARYSILENGFLHI---QSAH 3774



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L IA V+  D+G YT +A N AG +  S  +TV 
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAI 4187



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP + Q P N  +  G  A     +       +TW +N + +  +    I T  N  +L 
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLE 577

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
           +++ + +D+G Y  +  +  G    S +L V+ P +  V  +   +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSF 623



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 790  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 847  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 897  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 951

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 952  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 1236

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQE 1260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFET-RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            VY PP     L +    +    H  T   +  G+P+  + WLK+G  ++A+         
Sbjct: 1635 VYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR--IEA 1692

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
            G   L+++S    D G+Y C A S  G  E K  + V     IE
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 1736



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 2039 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDID 2097

Query: 860  IRV 862
            +RV
Sbjct: 2098 LRV 2100



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 2099 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 2156

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              + ++     +QD+G YTC A +  G  E
Sbjct: 2157 SVLKIE--DAQVQDTGRYTCEATNVAGKTE 2184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R+  NI  VE  +V L C     G     + WF +G P+   +  R         L L+ 
Sbjct: 2391 RSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQ 2446

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
               ED+G YTC   N  GE      L V+    ++ E+
Sbjct: 2447 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN 2484



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W+KDG P++ S+ +  I + G + L +M    EDAG YT    N  GE
Sbjct: 2414 PLPSITWFKDGWPVSLSNSV-RILSGGRM-LRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P+  + WYKDG+P+ +   +    N G+ +L I   +  D G YT  A N  GE
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGE 2753



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG P+ +S ++      G   L I    V DAG YTC A N  G+ +   ++ ++
Sbjct: 2811 WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+ N++EG     EC    +  P +T  W+ NG+ I          D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPVIT--WYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2177 EDSGTYMCKATNKLG 2191
             D+G Y+C+A N  G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 3147 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
               L +      DSG YTC A +  G A+
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 3449 KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 3504

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3536



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 3769

Query: 325  VRNTQKSDSGHYTLLAENPNG 345
            +++   +D+G Y  +A N  G
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAG 3790



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 4106 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162

Query: 860  IRV 862
            + V
Sbjct: 4163 LTV 4165



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 4419 CVATNEAGVVERS 4431



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 4427 VVERSMSL 4434



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 4433 SLTLQSPPIITLEPVE 4448



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKI 876



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + W KD R +  S+ +T F N G + + I+S  + DAG Y C A N+ G
Sbjct: 1952 ITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +  A  +DTG YT  A
Sbjct: 2029 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVA 2085

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 3261 GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTS 4160

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 4161 TKLTVHVPPRIRSTEGHYTVNENSQAI 4187



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP--FATGSR 3743
            T  D    PP   +++ +N+ V  G      C +    D    + W  N R    A  +R
Sbjct: 512  TFFDVSEPPP--VIQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPAR 567

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            + TL +   ++L++  +   DAGEY C  +++ GS+  +  +T
Sbjct: 568  IRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 700  EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 754

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 755  GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 798



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 1236

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTV 1264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++ +LL SG    T  + G + +DI      
Sbjct: 1929 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNRLL-SGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1985 DAGIYKCVAINSAG 1998



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 1176 KPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +P      S+P    V+ GK+I LEC ++ +  PT  V W  +G  +      +   +  
Sbjct: 2289 RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGH 2346

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
             + L  IH   +DTG Y   AVN  G       + V     I+ + ++ + I  ++
Sbjct: 2347 ILQLKNIHV--SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+ E QS    C +   P P   + W+ +G+ LQ    +   +   F  L I  V    +
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPE--ITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545

Query: 1915 GEYTCKAINNLGQAVSSIRLNV 1936
            G YTC A +  G    S  LNV
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNV 2567



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P D+ +  NS     C       ++  + WF +G PL +   ++ +   G   L+I    
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPAT--ITWFKDGTPLESNRNIRILP--GGRTLQILNAQ 2637

Query: 3624 QRDAGLYTCKATNRHGE 3640
            + +AG Y+C ATN  GE
Sbjct: 2638 EDNAGRYSCVATNEAGE 2654



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 51/193 (26%), Positives = 78/193 (40%), Gaps = 41/193 (21%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            P+  + W+ +G+P  +   V+   + G   L I      D G YTC A+N          
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASN---------- 2749

Query: 3785 ITCSAKRDIVLESQLPQGMSGEKIKE----LERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            I    + D  +  Q+P   S +K+ E    L+ GR  +A  ++ I++ P           
Sbjct: 2750 IAGEDELDFDVNIQVPP--SFQKLWEIGNMLDTGRNGEA--KDVIINNP----------- 2794

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
                  +   C       P L   WY++G  L S  +   +   G V L I     ED+G
Sbjct: 2795 ------ISLYCETNAAPPPTLT--WYKDGHPLTSSDKV-LILPGGRV-LQIPRAKVEDAG 2844

Query: 3901 EYICRAVNDFGED 3913
             Y C AVN+ GED
Sbjct: 2845 RYTCVAVNEAGED 2857



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+I++   S + E    P       + W+ +G PL +  +V  +   G  +L+I      
Sbjct: 2788 DVIINNPISLYCETNAAP----PPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVE 2841

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            DAG YTC A N  GE ++   ++V
Sbjct: 2842 DAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T+  T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 3354 TLVDTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 3409

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3519

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 3520 ILKV-------LEPPHINGSEEHEEI 3538



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 4438 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4494

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 4495 YIADAQ---KEDTSEFECVARNLMGS 4517



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P+     KN   T G  V +  + T    P  ++ W  N   +   HR++ T D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG- 664

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
               L I  A  +D G Y C A+N+ G     S+++
Sbjct: 665  --TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI W  N   +    R+++TSD    TL + +   +D+GIY C A N  G    +ST
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 3001 V 3001
            +
Sbjct: 696  L 696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 756

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 757  -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 794  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 854  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICV 1339

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 1340 AVNEAGTTERKYNLKV 1355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAG 1345



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   P  + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNF---PNEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 1493

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 1471 VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 1527

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 1528 SNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915

Query: 1136 ETRSSID 1142
                S++
Sbjct: 1916 HEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G  + LE  +  +  PT  V W  +G P+ +    +   D G++ L +   +  DTG
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTG 2359

Query: 2049 TYMCKATNAVG 2059
             Y+C A N  G
Sbjct: 2360 RYVCVAVNVAG 2370



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 8/144 (5%)

Query: 3962 DDLYDVDKKQPPRFVTQIQS--QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            D  YD+    PP  +   +S    S+VE  +    C+ +  G P   + WF +G P+   
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLS 2430

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
            N    +   G   +       ED+G+Y C   N  G +     +     P IV ++ L +
Sbjct: 2431 NSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-E 2487

Query: 4080 HMKSIEKIREMEASWQVTPEQVVE 4103
             +K  EK + +  + +VT   V E
Sbjct: 2488 DVKVKEK-QSVTLTCEVTGNPVPE 2510



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + W+ +G  L+S    R     G   L IL    +++G Y+C A N  G+ 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 1929 VSSIRLNV 1936
            +    + V
Sbjct: 2656 IKHYEVKV 2663



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV 3622
            +P ++ +  N++   EC    +  +S+   W+ +G+PL +   V    + G   L+I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 3623 YQRDAGLYTCKATNRHGE 3640
               D G YTC A+N  GE
Sbjct: 2736 QISDTGRYTCVASNIAGE 2753



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDL 1509
            PK ++  +    +  EC+   +  ++L   W+K+GQP+        I   G+  L I + 
Sbjct: 2681 PKEVKIKVNNT-LTLECEAYAIPSASLS--WYKDGQPLKSDDHVN-IAANGHT-LQIKEA 2735

Query: 1510 IAEDSGIYTCRAVNLVGTDEV 1530
               D+G YTC A N+ G DE+
Sbjct: 2736 QISDTGRYTCVASNIAGEDEL 2756



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/120 (30%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            EDS +Y  R  V   +  A    + L     +   +SA  EC     P P  R  W  +G
Sbjct: 2856 EDSLQYDVRVLVPPIIKGAN---SDLPEEVTVLVNKSALIECLSSGSPAP--RNSWQKDG 2910

Query: 1885 K-VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            + +L+  H    SN      L IL     D G Y C A N  G A     LNV    S+I
Sbjct: 2911 QPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2967



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 2986 CEVSGFPPPDL--SWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 3041

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 3042 GESKKKFSLTVYVPPS-IKDHDSES 3065



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 8/151 (5%)

Query: 2194 VNTCTLKVAGHRNI-ILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV---TELR 2249
            +NT TL V G R + I+  +  +G E       Q   ++ +       PP      +E  
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESL 3066

Query: 2250 GTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
               +V EG +   EC+   V  P   I +Y NG+ +  +    I  D G + L I+    
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
             D G+Y  +AIN  G       + V    SI
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 3447 VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 3502

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 3503 KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 3674

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 3675 RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 3722



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 3979

Query: 724  AVLHV 728
              LHV
Sbjct: 3980 VTLHV 3984



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 14/133 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 4217 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 4268

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 4269 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 4322

Query: 3219 SGEYVCRAYNKYG 3231
            SG YVC A N  G
Sbjct: 4323 SGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W +N + +    R+R T D    TL I +    DAG+Y C A N AG
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V    PV  +C+    G+P   I W+ + R   +GS   T  + G I +DI+     
Sbjct: 1929 NETVLVSNPVQLECKA--AGNPVPVITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3764 DAGEYTCRATNKWGS 3778
            DAG Y C A N  G+
Sbjct: 1985 DAGIYKCVAINSAGA 1999



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 3826 VSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNEQ--PIKLNTNTLIVP 3015

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            G  +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN+ GE+   
Sbjct: 2990 GFPPPDLSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 3108 ILADGQMLH 3116



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 2996 LSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 1003 TKKDI 1007
                I
Sbjct: 3054 VPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 724  AVLHVTPRATIERTSQHPETL 744
              L+V    TI       E L
Sbjct: 3332 FNLNVYVTPTIRGNKDEAEKL 3352



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 1791 LGE 1793
             G+
Sbjct: 3605 AGD 3607



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 3712 PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 3768

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 3769 HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 3887

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 3888 TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 3936

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 3937 LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 3985



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 3952

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 3993



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 4260 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 4312

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  +T +   ++   G      C       P +   W  N   I   HRYR T D   
Sbjct: 609  QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDMFIVGSHRYRMTSD--- 663

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
              L I     +D+G Y C A+N  G      TL+
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 1273 TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVT 1329

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 1330 PYDNGEYICVAVNEAGTTERKYNLKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 3510 MKV 3512
            +KV
Sbjct: 1353 LKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAG 1438



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 1671 SKKSI 1675
               S+
Sbjct: 1917 EPPSL 1921



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1946 GNPVPVITWYKDN-RLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L  +T +EG  I      E  G P   + W K G  +   S        G   L +    
Sbjct: 2203 LTQLTVIEGNLISL--LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE 2260

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
              D+  Y+C A +  G A+ +  L V  R TI  +  HP
Sbjct: 2261 KSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHP 2299



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG  + L  +      PNL   W K G  + T +  +     G   L I+     D+ 
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLI--WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2265

Query: 2714 IYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            +Y+C A+N+ G A    ++++  R  +     HP  +
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W+++G P+  +  +  + D G++ L +K ++  D+G Y C A+N  G     
Sbjct: 2318 GIPPPTVTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2375

Query: 1798 STLFVQSKASL 1808
              L V +  S+
Sbjct: 2376 YDLSVHAPPSI 2386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P   + W ++G P+E++  +  +   G   L +     +++G Y+C A NE GE +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 2963 PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GG 3017

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 3430

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 3431 FAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 3791



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 3744 ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3801

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 3802 VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 3852

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 3853 YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 4260 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 4312

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 945  WLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            W ++ R V  +  +RI T  N   ++L +KSV  +DAG Y C   +  G +  S  LT+ 
Sbjct: 553  WQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 1002 -VTKKDIIAESQHPGGLEKIQYLEDASRYSK 1031
               K  ++ ++Q   G  ++  +  A+ Y K
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPK 640



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    PK+ ++   G  V   C          K+ W  N   +   HR+R   D     
Sbjct: 612  PKVTVMPKN-QSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG---T 665

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L I +   +D+GIY C A N  GTD+ +  L
Sbjct: 666  LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            +T+T+   +   + +  + A    Q  + + V   P+  R   +++   G  V + C  Q
Sbjct: 1137 ITETRTSDSGMYLCVATNIAGNVTQAVK-LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G     + W   G  +        +     +++D  +  P D+G+YTC ATN  G   
Sbjct: 1196 --GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT--PSDAGIYTCVATNIAGTDE 1251

Query: 1396 TSCALRV 1402
            T   L V
Sbjct: 1252 TEITLHV 1258



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            +L C +E  G P+  + W+ +   VT  S  +T  + G + L +  AT  D G Y+ +A+
Sbjct: 1379 NLFCEVE--GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAI 1434

Query: 1256 NHLGSAHTSAIVRVIERSDIV-TDTQNEQAI 1285
            N  G++     + V+    I+ T+  NE ++
Sbjct: 1435 NIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 1465



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   + WYKD R ++ S+ +T   N G + ++I   +  DAG Y   A+N  G      
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 859  SIRVAARSTVT 869
            S++V    +++
Sbjct: 2005 SLQVHVAPSIS 2015



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ID  V + P  +   +++ +V+  Q V   C+ + +    L   W K+G P+ +      
Sbjct: 2096 IDLRVYVPPNIMGEEQNV-SVLISQAVELLCQSDAIPPPTLT--WLKDGHPL-LKKPGLS 2151

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            I +   V L I D   +D+G YTC A N+ G  E
Sbjct: 2152 ISENRSV-LKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3694 PPRFTVE-IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP    E   +++ V E   V   C V   G+P   I W  +G+P       H ++   F
Sbjct: 2477 PPHIVGENTLEDVKVKEKQSVTLTCEV--TGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2534

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I  +     G YTC A++  G
Sbjct: 2535 --LQITNVQVPHTGRYTCLASSPAG 2557



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  + E    P+  + W+K+G  L +   +    +    TL I   +  D+G YTC A+N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASN 2749

Query: 2722 LLGE 2725
            + GE
Sbjct: 2750 IAGE 2753



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 2/72 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KDG+P+        F + G + L I +  + D G Y C A N  G A   
Sbjct: 2898 GSPAPRNSWQKDGQPLLEDDH-HKFLSNGRI-LQILNTQITDIGRYVCVAENTAGSAKKY 2955

Query: 997  ANLTIVTKKDII 1008
             NL +     +I
Sbjct: 2956 FNLNVHVPPSVI 2967



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 14/146 (9%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYVALDLLSVY 1376
            N+  V    + L C +   G     + W  N +PIK  T     P        L ++   
Sbjct: 2973 NLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTNTLIVPGGR----TLQIIRAK 3026

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              D G YTC A NQ GE+    +L V       ++      L  +   E TS      + 
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTS----VSLE 3080

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHV 1462
             ES  + P  +T  K+   + E  HV
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHV 3106



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 3073 EGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 3129 VCRAINVAG 3137



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W +N K IE+S  +      G   + I+  +  D G Y C ASN+ G+
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 3318

Query: 146  CTARNQYGE 154
            C A N  GE
Sbjct: 3319 CVATNPAGE 3327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 3357 DTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 3412

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 3413 CVASNRAGVDNKHYNLQV 3430



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 3556 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613

Query: 860  IRV 862
            +RV
Sbjct: 3614 VRV 3616



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 3728 KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 3782

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  +G+ ++   R + ++      L+I  V   DAG YTC A N  G ++ S KL V
Sbjct: 4110 ITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 4364 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 4418

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 4419 CVATNEAG 4426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPP   VP  +VT   G +      I    D    + W +N + +  +     I     +
Sbjct: 519 PPPVIQVP-NNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEP-ARIRTLANL 574

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQ 739
           SL++ S+   D+GEY C   S  G +     L V   P+ T+   +Q
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 702  PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 757

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 758  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 799



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 1007 NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 1063

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 1064 VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 1118

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 1119 LISPFSPRH 1127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 1253

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQE 1277



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +E  P P   + WY +   +      +T N+     L +     ED+G Y+CKAIN  
Sbjct: 1382 CEVEGTPSPI--IMWYKDNVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIA 1437

Query: 1926 GQAVSSIRLNVQSKESII 1943
            G +     ++V    +II
Sbjct: 1438 GTSQKYFNIDVLVPPTII 1455



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1844 PRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            P  I   N P ++S    +    EC+++  P P+  + W+ +GK L  G       D G 
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRG- 1507

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L +      D G Y C   N  G+    I+L +    SI
Sbjct: 1508 QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 1548



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+     +   + G   L+I+ A   
Sbjct: 1650 NKQVVIAHSLTLECKAA--GNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEI 1705

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 1838 VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 1894

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 1895 RYTCVATNAAGE 1906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 1912

Query: 2199 LKV 2201
            L V
Sbjct: 1913 LHV 1915



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 2001 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 2057

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 2058 GLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 2109



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V   +PV LE     +  P++   W  +G PV            G + L +  A   DTG
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLT--WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTG 2079

Query: 2049 TYMCKATNAVGE 2060
             Y C A NA GE
Sbjct: 2080 RYTCVAVNAAGE 2091



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 2034 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVN 2087

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 2088 AAGEKQRDIDLRV 2100



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  + + Q+ + L+  +  +  CQ   +  P +   W  +G PLL K   +   +   +
Sbjct: 2103 PPNIMGEEQNVSVLIS-QAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENRSVL 2159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V  +D+G Y C ATN+ G  E    +     P I
Sbjct: 2160 KIEDAQV--QDTGRYTCEATNVAGKTEKNYNVNIWVPPNI 2197



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G ++ LEC +Q +   T  V W  +G P+          E     L L +++  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSD 2357

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            +G Y C A N  G       L V A   +I   + P  +  ++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P   + W ++G P+  SN +  +   G   L +     ED+G YTC   N  GE
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P ++ +  N SA  EC  +     + R  W  +G+PLL     K +++    IL+I    
Sbjct: 2879 PEEVTVLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQ 2934

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQV 3649
              D G Y C A N  G A     L V
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNV 2960



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/71 (33%), Positives = 31/71 (43%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N   IE S+ L      G   L +      DSG YTC A N  G+A   
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 1798 STLFVQSKASL 1808
              L +Q   S+
Sbjct: 3237 YFLSIQVPPSV 3247



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 4165 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 4222

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 4223 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 4426


>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
            from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
          Length = 5635

 Score =  129 bits (312), Expect = 2e-28
 Identities = 107/384 (27%), Positives = 161/384 (41%), Gaps = 35/384 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  ++ A  E    G P P   W ++  P+      +    S   IL I    + D   +
Sbjct: 2884 VLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRILQILNTQITDIGRY 2941

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGT 4540
              VAEN  G+AK   NL V           VPPS     ++N+ V     + L  +V+G 
Sbjct: 2942 VCVAENTAGSAKKYFNLNVH----------VPPSVIGPKSENLTVVVNNFISLTCEVSGF 2991

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P D+ WLKN + ++ +    I+   G  TL I+ A   D G+Y C+AIN AGE++    
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V +P       P  K  ++     E L    V EG ++   C+    P P + WYK  
Sbjct: 3050 LTVYVP-------PSIKDHDS-----ESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3097

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            ++I  S + ++   AD   L I +A   D G Y C A N AGR      L V  P   + 
Sbjct: 3098 RMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155

Query: 4721 LPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                 P R+++V     P       T    PTI WL+    I  +   ++      + L 
Sbjct: 3156 -----PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVE 4803
            I  +   D+G +TC A+   G+ +
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQ 3234



 Score =  119 bits (287), Expect = 2e-25
 Identities = 103/380 (27%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 1148

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 1149 LCVATNIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 1257 HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 1305

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   D   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 1306 EL--TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               +T   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 1364 KEQVT---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKL 1418

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 1419 FRATPEDAGRYSCKAINIAG 1438



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/371 (27%), Positives = 155/371 (41%), Gaps = 39/371 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + W R +  ++ +   +I T +  S L ++ V   D+  +  +  + GG++  S  L V+
Sbjct: 551  LTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E          PP  T+  +N + T G  V +    TG     + W  N   +    R +
Sbjct: 610  E----------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYR 659

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             +  DGT  L I  A P+D+G Y C+A NSAG                DK     +   A
Sbjct: 660  -MTSDGT--LFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEA 701

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P +++    + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+
Sbjct: 702  P-KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLK 758

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I E    D GDY CVA N AGR T    L V  P      PA     D+ +  G      
Sbjct: 759  IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLP 813

Query: 4742 TQITSKIKPTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              +    +PTI+W R +   I   P     I +     L I N +  D GT+ C A    
Sbjct: 814  CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 4800 GQVETSAKLVV 4810
            G++++   + V
Sbjct: 874  GKIQSETTVTV 884



 Score =  115 bits (276), Expect = 5e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 4237

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 4238 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 4287

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 4288 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 4344 YVKEP-------PVFKG-DYPSNWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 4388

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 4389 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 4441

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 4442 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 4497

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 4498 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score =  113 bits (271), Expect = 2e-23
 Identities = 103/405 (25%), Positives = 158/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 1227

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 1282

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + EDGT  L+I    P D+G+Y CVA+
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAV 1341

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDK---------------EQVTNVSVLLNQLTNLFCEVEG 1386

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 1387 TPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P      ++ V   +    + Q+     P I W ++G  L    P
Sbjct: 1445 NIDVLVPPTIIGTNFP-----NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 1500 NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  110 bits (264), Expect = 1e-22
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI-VPGGRTLQI 3022

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N+ G +K   +L V           VPPS     + +   VNV
Sbjct: 3023 IR-AKVSDGGEYTCIAINQAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 3071

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 3129

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 3130 CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 3174

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 3235 KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  109 bits (261), Expect = 3e-22
 Identities = 100/368 (27%), Positives = 151/368 (41%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 3271 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 3330

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         TL   ++N+        + + TGT P  + WLKNG  
Sbjct: 3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI--------ECRATGTPPPQINWLKNGLP 3382

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 3383 LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 3438

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 3439 ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 3486

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 3487 HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 3541

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 3542 VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 3598

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 3599 CLASSPAG 3606



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 3054 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI--LAD 3111

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 3112 GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 3161

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 3267

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 3268 CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L  +V         + + T    P I WL+ G  +P
Sbjct: 3328 EDRIFNLNVYVTPTIRGNKDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLP 3384

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 3385 LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 3420



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/407 (25%), Positives = 164/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 4043

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 4093

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMA 4150

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 4151 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 4194

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 4195 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 4250 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 4301

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+    + VK
Sbjct: 4302 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346



 Score =  106 bits (255), Expect = 2e-21
 Identities = 91/382 (23%), Positives = 165/382 (43%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P++ W ++  P+K + + +I     K  ++  Q    D   +  VA +  G
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAG 1719

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWL 4548
              +    + V          +VPP+     +     V    L+ LD  VTG+ P  + WL
Sbjct: 1720 EKEIKYEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWL 1769

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P  
Sbjct: 1770 KDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP-- 1825

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  K++         L +++V + + +   C   G P P++ W K D+ +  ++ 
Sbjct: 1826 -----PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ- 1871

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              +   +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L 
Sbjct: 1872 GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LN 1929

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            + V+    P Q + +      P I W ++  L+  +     ++ G   ++ I +    D 
Sbjct: 1930 ETVLV-SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDA 1986

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A  +AG  E    L V
Sbjct: 1987 GIYKCVAINSAGATELFYSLQV 2008



 Score =  105 bits (253), Expect = 3e-21
 Identities = 122/485 (25%), Positives = 195/485 (40%), Gaps = 59/485 (12%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            ++ G P P +SW + + P+    K +       G  +L I +    D GEYTC A NQ G
Sbjct: 2987 EVSGFPPPDLSWLKNEQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 154  EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
            E+      +VY+ P                   S ++E ++                  Y
Sbjct: 3043 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITW--------Y 3094

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
             NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 3095 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 3152

Query: 268  IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
            I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 3153 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIA 3212

Query: 327  NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 3213 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 3253

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                         D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 3254 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREG 505
            +  L I     SD+G  TCVA N +GE      LNV     +   K   E+  TL     
Sbjct: 3302 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTL---VD 3357

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              + +  RA GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A
Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVA 3415

Query: 566  QNVAG 570
             N AG
Sbjct: 3416 SNRAG 3420



 Score =  105 bits (252), Expect = 4e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 3420

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 3421 VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 3471 RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 3526

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 3527 -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 3573

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 3574 -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 3629

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 3687

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 3688 ANYTCVASNIAGKTTREFILTV 3709



 Score =  105 bits (251), Expect = 5e-21
 Identities = 101/395 (25%), Positives = 161/395 (40%), Gaps = 35/395 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP    + Q   V   +      + D  P P + W ++  P+   P   I     +S+L 
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTS 4527
            I    V+D+  +   A N  G  + + N+ +           VPP+   + +   + V  
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW----------VPPNIGGSDELTQLTVIE 2210

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G L+ L  + +G  P ++ W K G  V  D   ++    G   L I  A   D+  Y CV
Sbjct: 2211 GNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCV 2270

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG A+ +    V +  T       T + + P EI       IV  G++I   C++ 
Sbjct: 2271 ASNVAGTAKKEYNLQVYIRPT------ITNSGSHPTEI-------IVTRGKSISLECEVQ 2317

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PTV W K G  LIK +K  ++    + + L++      D G Y CVA N AG    
Sbjct: 2318 GIPPPTVTWMKDGHPLIK-AKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2374

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V  P     +       +I V E        + +    P+I W ++G  +  +  
Sbjct: 2375 KYDLSVHAPPSI--IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNS 2432

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +++  G   +L +  T  ED G +TC    AAG+
Sbjct: 2433 VRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score =  104 bits (250), Expect = 7e-21
 Identities = 109/409 (26%), Positives = 167/409 (40%), Gaps = 41/409 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 850

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 851  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 902

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 903  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 959

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 960  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 1003

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSS-AKFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYAK 1061

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +   L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V
Sbjct: 1122 PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score =  104 bits (250), Expect = 7e-21
 Identities = 96/377 (25%), Positives = 155/377 (41%), Gaps = 34/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P  +W + +  +  +P   + +  +   L I +V ++D   +  VA N  GT   +
Sbjct: 916  GNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT 972

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             ++VV           V P+     Q ++   G  V L  K +G     V W K G+ + 
Sbjct: 973  TSVVVH----------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                      DG+  L ++    ++SG+Y C A N+AG A+   +  V +       +P+
Sbjct: 1023 TSSAKFSAGADGS--LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYV-------RPR 1073

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT- 4674
                       +P++  ++A G+ +   C++   P P + W K  +LI P   F    T 
Sbjct: 1074 VFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITWAKETQLISP---FSPRHTF 1129

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +++I+E    D G Y CVA N AG VT A KL V  P +    P     + + V  
Sbjct: 1130 LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQV 1184

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            GQ             P I W + G+ +    D +      +  L I      D G +TC 
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCV 1242

Query: 4795 ATTAAGQVETSAKLVVK 4811
            AT  AG  ET   L V+
Sbjct: 1243 ATNIAGTDETEITLHVQ 1259



 Score =  104 bits (250), Expect = 7e-21
 Identities = 95/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKE 1817

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 1818 FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 1868 NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 1919

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK ++L+  S    M+  
Sbjct: 1920 SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFL 1970

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1971 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 2025

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +    DTG +TC 
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSAQISDTGRYTCV 2084

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 2085 AVNAAGEKQRDIDLRV 2100



 Score =  104 bits (250), Expect = 7e-21
 Identities = 102/369 (27%), Positives = 147/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W + +  I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 3237 YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 3286

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 3287 IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 3339

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +  L D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 3340 PTIRGNKDEAEKLMTLVDT------SINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 3391

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 3392 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 3448

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3506

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 3507 IASNEAGEV 3515



 Score =  104 bits (249), Expect = 9e-21
 Identities = 101/398 (25%), Positives = 164/398 (41%), Gaps = 40/398 (10%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVF 4474
            KM    V      + E +  G P+P+I WY++N  +  S      TF  +  +I I    
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSM---TFLNRGQIIDIESAQ 1982

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + D+ ++  VA N  G  +   +L V           V PS + +   V V     VRL+
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH----------VAPSISGSNNMVAVVVNNPVRLE 2032

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +  G     + WLK+G  V     N +    G   L +  A   D+G+Y CVA+N+AGE
Sbjct: 2033 CEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             + D +  V +                PP I+   ++  V   QA+E  C+    P PT+
Sbjct: 2092 KQRDIDLRVYV----------------PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135

Query: 4655 QWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             W K G  L+K      +S + +   L+I +A  +D G Y C A N AG+      + + 
Sbjct: 2136 TWLKDGHPLLKKP---GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHE 4772
             P    N+     L  + V EG       + +    P + W ++G+ ++ ++     I  
Sbjct: 2193 VP---PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS 2249

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G    L I    + D   ++C A+  AG  +    L V
Sbjct: 2250 GGRQ-LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286



 Score =  102 bits (245), Expect = 3e-20
 Identities = 96/389 (24%), Positives = 155/389 (39%), Gaps = 31/389 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  +   R E E  G P P + W ++  P+ +  +  +   S   IL +    + D+  +
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRY 2081

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G  +   +L V           VPP+     QNV+V   Q V L  +     
Sbjct: 2082 TCVAVNAAGEKQRDIDLRV----------YVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  + WLK+G  +       I E      L I +A  QD+G+Y C A N AG+   +   
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNVAGKTEKNYNV 2189

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             + +P       P    +       + L    V EG  I   C+  G P P + W K   
Sbjct: 2190 NIWVP-------PNIGGS-------DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +      ++   +    L+IS A   D   Y CVA N AG       L+V       N 
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
             +     +I+V  G+    + ++     PT+ W+++G  + +    +++ EG+  +L + 
Sbjct: 2296 GSHPT--EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQLK 2351

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            N +  DTG + C A   AG  +    L V
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380



 Score =  101 bits (243), Expect = 5e-20
 Identities = 101/380 (26%), Positives = 148/380 (38%), Gaps = 35/380 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 1006 GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPGG-EESGEYVCTATNTAGYAKRK 1063

Query: 4496 ANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V  + R    + G+           ++V +G+ V L  +V    P  + W K  + 
Sbjct: 1064 VQLTVYVRPRVFGDQRGLSQDK----PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 1119

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P          G+  + I E    DSG Y CVA N AG      +  V          
Sbjct: 1120 ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV---------- 1167

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S 
Sbjct: 1168 ------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIV 4731
               + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V
Sbjct: 1222 P--DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 1279

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                Q  +F        KPTI+WL  G  L    P   ++ +G   +L+I +    D G 
Sbjct: 1280 A--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGE 1335

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A   AG  E    L V
Sbjct: 1336 YICVAVNEAGTTERKYNLKV 1355



 Score =  101 bits (241), Expect = 8e-20
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 3912

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 3970

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 3971 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 4013

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 4014 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 4071

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 4072 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 4126 RVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 1242 VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 1293

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 1294 PKPTIKWLHNGRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 1353 LKVH----------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 1400

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 1453

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 1506

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 1507 GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 1561

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 1562 NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 1619

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 1620 VANVAGTAEKS 1630



 Score =  100 bits (239), Expect = 1e-19
 Identities = 106/423 (25%), Positives = 169/423 (39%), Gaps = 31/423 (7%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKK-MQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T +   A  +ER + G      P I  +  ++  +V E +      E  G P+P I W++
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK 2515

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRR 4505
            +  P++   D   H  S    L I  V V  +  +  +A +  G    S +L V      
Sbjct: 2516 DGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
             G G    P      ++V V       L  +     P  + W K+G  ++ +   +IL  
Sbjct: 2574 AGVGSDGNP------EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL-- 2625

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             G  TL IL A   ++G+Y CVA N AGE     E  V +P   +K         +P E+
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL-SPKEV 2684

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
                K K+      +   C+    P  ++ WYK  + +K   +  ++  A+ +TL+I EA
Sbjct: 2685 ----KIKV---NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA--ANGHTLQIKEA 2735

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-------VVYEGQPA 4738
               D G Y CVA N AG   +   + +  P     L  +  + D         V    P 
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +  +   PT+ W ++G   P T   +++      VL I     ED G +TC A   
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNE 2853

Query: 4799 AGQ 4801
            AG+
Sbjct: 2854 AGE 2856



 Score =   99 bits (238), Expect = 2e-19
 Identities = 82/299 (27%), Positives = 123/299 (41%), Gaps = 40/299 (13%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P    +  G     + ++ G P P VTW K+G  LI +   EI+    H  L+++N   S
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGH-ILQLKNIHVS 2356

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            D+G Y  +A N  G       L+V +P  S + + RS                       
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHRS----------------------- 2392

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ + V +   V+        C  +G P P +TWF +   +    + +IL   SG   L 
Sbjct: 2393 PENISVVEKNSVS------LTCEASGIPLPSITWFKDGWPVSLSNSVRIL---SGGRMLR 2443

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +   T+ D+G  TCV RN +GE      L+V+    +V    +E    + V+E + V L 
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE---DVKVKEKQSVTLT 2500

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG P+    +   H   G   L I   +      Y C A + AG
Sbjct: 2501 CEVTGNPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 35/375 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E E  G P P + W ++  P+  +   +I       IL ++ + V D+  +  VA N  G
Sbjct: 2313 ECEVQGIPPPTVTWMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT---LTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
                  +L V            PPS      + +N++V     V L  + +G     + W
Sbjct: 2371 MTDKKYDLSVH----------APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITW 2420

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G  V   + N +    G   L +++   +D+G+Y CV  N+AGE R      V +P 
Sbjct: 2421 FKDGWPVS--LSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP- 2477

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                  P     N        L+D  V E Q++  +C++ G P+P + W+K  + ++  +
Sbjct: 2478 ------PHIVGENT-------LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               +   +    L+I+       G Y C+A + AG  + +  L V        + +    
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
             D+ V    P     +  S    TI W ++G  +    + +++  G    +L  N  E++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL--NAQEDN 2640

Query: 4788 TGTFTCRATTAAGQV 4802
             G ++C AT  AG++
Sbjct: 2641 AGRYSCVATNEAGEM 2655



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 95/380 (25%), Positives = 157/380 (41%), Gaps = 34/380 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E +  P P + WY++  P+ +S    I       +L I +  VED+  +  VA N  G  
Sbjct: 2800 ETNAAPPPTLTWYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857

Query: 4493 KCSANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                ++ V+     +G    +P       + V V   +   ++   +G+      W K+G
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLP-------EEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2910

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            + +  D  +K L       L IL     D G+Y CVA N+AG A+               
Sbjct: 2911 QPLLEDDHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAK--------------- 2953

Query: 4612 PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             K      + PP +I P  + + V     I  +C++ G P P + W K ++ IK +    
Sbjct: 2954 -KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +       TL+I  A   D G+Y C+A N AG       L V  P    +  + + L  +
Sbjct: 3013 I--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-LSVV 3069

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG     + +  +   P I W + G +I E+   +++ +G   +L I      DTG 
Sbjct: 3070 NVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQ 3127

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + CRA   AG+ + +  L V
Sbjct: 3128 YVCRAINVAGRDDKNFHLNV 3147



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 88/301 (29%), Positives = 127/301 (42%), Gaps = 37/301 (12%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 1051

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 1052 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 1090

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 1091 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 1143

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 579  Y 579
            +
Sbjct: 1257 H 1257



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF 4137

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 4138 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 4184

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 4185 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 4241

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 4242 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 4286 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKAIG 4341

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 4394

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 4395 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 88/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 1227

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 1268

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 1269 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 1318

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
             G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ + ++V  
Sbjct: 1319 DGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVTNVSVLL 1374

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 1375 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCK 1432

Query: 565  AQNVAGST 572
            A N+AG++
Sbjct: 1433 AINIAGTS 1440



 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 96/388 (24%), Positives = 160/388 (41%), Gaps = 36/388 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E        E  G PLP I W+++ +P+  S   +I   S   +L + Q  +ED+  +
Sbjct: 2398 VVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRMLRLMQTTMEDAGQY 2455

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTG 4539
              V  N  G          EE++  G   +VPP      T ++V V   Q V L  +VTG
Sbjct: 2456 TCVVRNAAG----------EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                ++ W K+G+ +Q D  + I+   G   L I       +G+Y C+A + AG      
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
               V +      P      ++  PE      D  V         C+    P  T+ W+K 
Sbjct: 2564 SLNVFV-----SPTIAGVGSDGNPE------DVTVILNSPTSLVCEAYSYPPATITWFKD 2612

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP---D 4716
               ++ ++  ++       TL+I  A  ++ G Y CVA N AG +    ++KV  P   +
Sbjct: 2613 GTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2670

Query: 4717 QADNL-PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
            + D   P L+P +++ +        + +  +    ++ W ++G   P   D  +    N 
Sbjct: 2671 KGDLWGPGLSP-KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ--PLKSDDHVNIAANG 2727

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              L I      DTG +TC A+  AG+ E
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDE 2755



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 64/209 (30%), Positives = 88/209 (42%), Gaps = 8/209 (3%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYP 421
            +   QY    +    EER       L P  +      +D  V E +     C VTG P P
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            E+TW  + + +++D  H I+   SG   L ITNV +  +G  TC+A + +G  +    LN
Sbjct: 2510 EITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V     +           + V    P  L   A   P   ITW KDG P+  N  +RI  
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2626

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G  TL I  A+  +A  Y C A N AG
Sbjct: 2627 --GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 3896

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 3951

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 4006

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 4007 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 4065 GTALGKIKL 4073



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 99/397 (24%), Positives = 159/397 (40%), Gaps = 41/397 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N  V  
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1934

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+ + +        L       + I  A   D+G Y+CV
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1992

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1993 AINSAGA----TELFYSL------------QVHVAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++ A   D G Y CVA N+AG    
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 2095 DIDLRVYVPPN-----IMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              +    N +VL I +   +DTG +TC AT  AG+ E
Sbjct: 2150 LSI--SENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 96/379 (25%), Positives = 156/379 (41%), Gaps = 42/379 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W   +  I  S  +++ +  T   L I+    +D+ ++  +A N  GT K +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            + L   E           P   +    + V  G +  ++ K +G  P  V W K   +++
Sbjct: 694  STLRYIEA----------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P   +  L  D    LL I E    D+G Y CVAIN AG A                   
Sbjct: 744  P---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI--------------- 785

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             T    +PP  I+   D  +  G  +   C + G P PT++W + D +   S+ F +S  
Sbjct: 786  -TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 4675 ADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +   T  L I   +  D+G Y C A N  G+  + ++  VT       L  ++P    V+
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK--IQSETTVTVTGLVAPLIGISPSVANVI 902

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQ      T +     P  +W++  A++ + P   +  +G+   L I     +D G +
Sbjct: 903  -EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEY 958

Query: 4792 TCRATTAAGQVETSAKLVV 4810
            TC A+  AG    +  +VV
Sbjct: 959  TCVASNVAGTNNKTTSVVV 977



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 86/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ +  G     + W 
Sbjct: 1533 KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY 1582

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 1583 KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 1638

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   CK  G P P + W K    +K +  
Sbjct: 1639 -----PMIEG-----NLATPLNKQVVI-AHSLTLECKAAGNPSPILTWLKDGVPVKANDN 1687

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             ++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 1688 IRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 1742

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G LI E   F+++  G    L+I      +T
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNT 1800

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTV 1822



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V+G P P+++W  N++ I+ + N  I+    G   L I    +SD G  TC+A N++G
Sbjct: 2986 CEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINQAG 3042

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 3043 ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3101

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 3102 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 3137



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 87/367 (23%), Positives = 146/367 (39%), Gaps = 17/367 (4%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W+++  P++++ + +I        L I     +++  ++ VA N  G       
Sbjct: 2603 PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V       +G +  P   L+ + V +     + L+ +        + W K+G+ ++ D
Sbjct: 2661 VKVYIPPIINKGDLWGPG--LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2718

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                I      +TL I EA   D+G+Y CVA N AGE   D +  + +P +  K      
Sbjct: 2719 DHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
              +         KD I+     I   C+    P PT+ WYK G  L    K   +     
Sbjct: 2777 MLDTGRN--GEAKDVII--NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PG 2829

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L+I  A  ED G Y CVA N AG  ++   ++V  P       +  P  ++ V   +
Sbjct: 2830 GRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP-EEVTVLVNK 2888

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  +   +    P   W ++G  + E    + +   N  +L I NT   D G + C A 
Sbjct: 2889 SALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRILQILNTQITDIGRYVCVAE 2946

Query: 4797 TAAGQVE 4803
              AG  +
Sbjct: 2947 NTAGSAK 2953



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 3607

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 3608 -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 3661

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 3662 LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 3712

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 3713 PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 3762

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 3763 LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 3815

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 3816 IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 3875

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 3876 CTVTNGAGDDKRTVDLTVQ 3894



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 3553 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 3602

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 3603 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 3640

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
              +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 3641 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 3696

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 3697 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 3752 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 4064

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 4065 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 4119

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 4120 VESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 1835 ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 1892

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 1893 AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1947

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1948 PVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 2000



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 13/217 (5%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
            R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  + + I +    KIL+N      L+I    +S++G+  C+A N +G+   +  + V 
Sbjct: 1767 MWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTD 542
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I + 
Sbjct: 1824 VPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSS 1879

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 1880 G--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 49/290 (16%)

Query: 293  PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGY 352
            P   +TWFK+G  L ++    I+      TL++ N Q+ ++G Y+ +A N  G ++    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            + V  P                       + ++    L+P+ VK+  +  +T       +
Sbjct: 2661 VKVYIPP-------------------IINKGDLWGPGLSPKEVKIKVNNTLT------LE 2695

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C     P   ++W+ + + ++ D +  I  N    H L I    +SD+G  TCVA N +G
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAG 2752

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNV----REGE--------PVVLNARAVGTPTP 520
            E      +N+      V P F + +   N+    R GE        P+ L       P P
Sbjct: 2753 EDELDFDVNI-----QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2807

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +TW KDG P+  + ++ I    G   L IPRAK  DA  Y C A N AG
Sbjct: 2808 TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAG 2855



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 52/350 (14%)

Query: 229 RLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGAD 282
           R L  +S   +S+     GE    +S+E   S   V      PPK+   P+N     G++
Sbjct: 569 RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSE 628

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
                  +G P+P++ W  N   ++ S+++ + +     TL ++N    D+G Y      
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY------ 679

Query: 343 PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
             GC+ ++      + T+              +Q  T   IE      AP+ + V  +  
Sbjct: 680 --GCLASNS-----AGTD--------------KQNSTLRYIE------APKLMVVQSELL 712

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L I      D+G 
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGD 769

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TCVA N++G    +  L+V        P F++  + +++  G  V L     G P P I
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI 824

Query: 523 TWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            W++ D +PI   P  +   +      L I    ASD   Y C A+N  G
Sbjct: 825 KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFG 874



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/302 (24%), Positives = 132/302 (43%), Gaps = 33/302 (10%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P+  K++       + +    P   ++W+K+GQ L  S+ H  I  + HT L+++  Q S
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANGHT-LQIKEAQIS 2738

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR--ETEERIEISEKA 389
            D+G YT        C+ ++  +A E   +  V  Q    +  + Q+  E    ++     
Sbjct: 2739 DTGRYT--------CVASN--IAGEDELDFDVNIQ----VPPSFQKLWEIGNMLDTGRNG 2784

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
             A         +DV         C     P P +TW+ +   +    + K+L+   G   
Sbjct: 2785 EA---------KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS--SDKVLILPGGR-V 2832

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I    + D+G  TCVA N++GE + Q  + V+    ++     +    + V   +  +
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSAL 2891

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +   + G+P PR +WQKDG P++ +   +  ++G    L I   + +D   Y C A+N A
Sbjct: 2892 IECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNG--RILQILNTQITDIGRYVCVAENTA 2949

Query: 570  GS 571
            GS
Sbjct: 2950 GS 2951



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/311 (23%), Positives = 128/311 (41%), Gaps = 40/311 (12%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3303

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 3304 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 3348

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               +EK +         D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 3349 ---AEKLMT------LVDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLL- 3392

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 3393 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 3448

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 3449 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 3505

Query: 563  CTAQNVAGSTA 573
            C A N AG  +
Sbjct: 3506 CIASNEAGEVS 3516



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 3625 TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 3682

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 3683 DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 3732

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 3790

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 3791 TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 3895 VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 3950 GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 3984



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 3769

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 3819

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 3820 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 3880 NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 3923

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 3980

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 3981 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4035

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 4036 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 9/163 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 2030 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSAQISDTGRYTCVAVN 2087

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 2088 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 2142

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P++  P L I  +   S L I  A+  D   Y C A NVAG T
Sbjct: 2143 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKT 2183



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 722  ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 779

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 780  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 829

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 830  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 885

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 886  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 936  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 986

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 987  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPGGE 1044

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 60/204 (29%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 380  EERIEISEKALAPQFVK-----VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            E+ ++   + L P  +K     + ++  V   K    +C  +G P P  +W  + + + +
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
            D +HK L N      L I N  ++D G   CVA N +G       LNV     V+ PK  
Sbjct: 2916 DDHHKFLSN---GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-- 2970

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
                 L V     + L     G P P ++W K+  PI  N    I    G  TL I RAK
Sbjct: 2971 --SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAK 3026

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD   Y C A N AG +  +  L
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSL 3050



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 101/475 (21%), Positives = 177/475 (37%), Gaps = 49/475 (10%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W +   P V   + +++  + +G V  + K +   D G YTC A N  GE  
Sbjct: 1852 GIPNPSITWLKDDQP-VNTAQGNLKI-QSSGRVLQIAKTLLE-DAGRYTCVATNAAGETQ 1908

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              + +                    VS  V+ +           +        +  T  +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
              +  ++   E   + +    + +     G      +TE+  SL     P I+       
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAG------ATELFYSLQVHVAPSISGSNNMVA 2022

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +      + + +  G P P +TW K+G   ++S  + +        L + + Q SD+G Y
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSP-VSSFSNGLQVLSGGRILALTSAQISDTGRY 2081

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T        C+      AV +  E              +QR+ + R+ +    +  +   
Sbjct: 2082 T--------CV------AVNAAGE--------------KQRDIDLRVYVPPNIMGEE--- 2110

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              Q+  V   +     C+    P P +TW  +   +       I  N S    L I +  
Sbjct: 2111 --QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---VLKIEDAQ 2165

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            + D+G  TC A N +G+T     +N+     +      +  + L V EG  + L   + G
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGS---DELTQLTVIEGNLISLLCESSG 2222

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             P P + W+K G P++ +   R+    G   L I  A+ SDAA Y C A NVAG+
Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 3447 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 3503

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 3560

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 3561 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
            P  V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 1460 PNEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 1510

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 1567

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 1568 ECETRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 1625

Query: 571  S 571
            +
Sbjct: 1626 T 1626



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/281 (24%), Positives = 114/281 (40%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 1851 NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 1901

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 1902 NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1938

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+ ++R +    +   L   +    + I +  +SD+G+  CVA N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQIIDIESAQISDAGIYKCVAIN 1995

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1996 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +  A+ SD   Y C A N AG
Sbjct: 2051 P-VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 2090



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 13/177 (7%)

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            V  D  V    + + +C   G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 1553 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 1609

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
            +SDS   TC   N +G       ++V      V P      +T LN  V     + L  +
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECK 1664

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P+P +TW KDGVP+  N  +RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 12/168 (7%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 4236

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G
Sbjct: 4292 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 4315

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K    + V+E          PP F     +  +    G
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE----------PPVFKGDYPSNWIEPLGG 4365

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 4366 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 4421

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 4422 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 4464

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 4465 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 4520



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 52/187 (27%), Positives = 81/187 (43%), Gaps = 11/187 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+   + +++  T G      C  TG P P++ W +ND  I   + +++    + +  L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM----TSDGTLF 667

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V+ 
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVME 722

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N AG 
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGR 780

Query: 572 TATRARL 578
              +  L
Sbjct: 781 ATGKITL 787



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
            L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 1307 LTGREPGISILEDGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 1363

Query: 398  CQ---DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
             +   +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GKILKLFR 1420

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
             T  D+G  +C A N +G +     ++V+    ++   F    S +  R+   V L  + 
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD---VALECQV 1477

Query: 515  VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 1533

Query: 572  TATRARL 578
             A   +L
Sbjct: 1534 QAKDIKL 1540



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 909

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 966

Query: 570 GS 571
           G+
Sbjct: 967 GT 968



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 4426 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 4480

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 4481 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 4521



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG +    C  +G P P + W      +  D   ++ +  SG   L I+    SD+ +
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL-SGGRQLQISIAEKSDAAL 2266

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             +CVA N +G    +  L V  +  +         + + V  G+ + L     G P P +
Sbjct: 2267 YSCVASNVAGTAKKEYNLQVYIRPTIT--NSGSHPTEIIVTRGKSISLECEVQGIPPPTV 2324

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            TW KDG P+I    + I  +G    L +     SD   Y C A NVAG T
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAVNVAGMT 2372



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 4314

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G   F   +  +  ++   P F   + +  +   G   +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG---FVKAIGFVYVKE--PPVFKGDYPSNWIEPLGGNAIL 4369

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/345 (22%), Positives = 130/345 (37%), Gaps = 37/345 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I +V + D   +  +A +  GT +      V E          PP       NV VT 
Sbjct: 484  LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE----------PPPVIQVPNNVTVTP 533

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L   +      ++ W +N + V+     +I       +L +      D+G+Y C+
Sbjct: 534  GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCM 592

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              +  G +       V                  PP++    K++    G  +   C   
Sbjct: 593  VSSEGGSSAASVFLTVQ----------------EPPKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P P + W   D  I  S  ++M  T+D  TL I  A P+D G Y C+A NSAG     
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRM--TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            + L+  +  +      +    +++V  G     + + +    P ++W +    +   P  
Sbjct: 694  STLRYIEAPK-----LMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPST 746

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +I +    +L I  T + D G +TC A   AG+      L V S
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D  V     T   C     P   +TWF +   +  + N +IL    G   L I N    
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQED 2639

Query: 459  DSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            ++G  +CVA N++GE      + V     I K  +  P    +   + ++    + L   
Sbjct: 2640 NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE 2697

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   P+  ++W KDG P+  +  + I  +G   TL I  A+ SD   Y C A N+AG
Sbjct: 2698 AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAG 2752



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 3762 ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 3876

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 3877 TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 3932 KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 74/294 (25%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            +G+         G P P + W ++GQ L   + H  ++TH    L++   +  DSG YT 
Sbjct: 3449 KGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG-MVLQLLKAETEDSGKYTC 3506

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            +A N  G +     L V  P           +I  +++ E     EIS     P     C
Sbjct: 3507 IASNEAGEVSKHFILKVLEP----------PHINGSEEHE-----EISVIVNNP-LELTC 3550

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                +   KMT       GRP P+        Q++            G   L I+   + 
Sbjct: 3551 IASGIPAPKMTWMK---DGRPLPQTD------QVQ---------TLGGGEVLRISTAQVE 3592

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G  TC+A + +G+   +  + V     +         + L  R+   V L  ++   P
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ---VTLECKSDAVP 3649

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P ITW ++G  +   P +RI +  G   L I  A   D A Y C A N+AG T
Sbjct: 3650 PPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGKT 3701



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L I  V   D+G  TC+
Sbjct: 4094 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQIAFVQPGDAGHYTCM 4149

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 4150 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4204

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 4205 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 61/277 (22%), Positives = 112/277 (40%), Gaps = 28/277 (10%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            ++   V    P  + +++NG  +  D   + L+E  +  L I +    D G YEC+A++S
Sbjct: 448  QIPCSVDSLLPFTLSFVRNGVTLGVD---QYLKESASVNLDIAKVTLSDEGFYECIAVSS 504

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG  R      VS                 PP +I+   +  V  G+    +C I+    
Sbjct: 505  AGTGRAQTFFDVS----------------EPPPVIQVPNNVTVTPGERAVLTCLIISAVD 548

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
              + W + D+ ++ ++  ++ RT    +L +      D G+Y C+  +  G    +  L 
Sbjct: 549  YNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            V +P +   +P     ++     G         T   KP I W      I  +  ++M  
Sbjct: 608  VQEPPKVTVMP-----KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            +G    L I N   +D G + C A+ +AG  + ++ L
Sbjct: 663  DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 12/201 (5%)

Query: 402  DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
            +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 955

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 956  GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 1010

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
             + W K G  +I     +  + G   +L +      ++  Y CTA N AG    + +L  
Sbjct: 1011 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068

Query: 581  XXXXXXXXXQKRLHLPRPTKV 601
                     Q+ L   +P ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEI 1089



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 12/188 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++V  +  VT G+     C +       +TW  NDR +R        +    N +L 
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVL 510
           + +V  +D+G   C+  ++ G +A    L V E  +V V PK        +   G  V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK------NQSFTGGSEVSI 631

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P+I W  + + I+ +   R+ +DG   TL I  A   DA  Y C A N AG
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688

Query: 571 STATRARL 578
           +    + L
Sbjct: 689 TDKQNSTL 696



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 47/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N+ G+++    L   
Sbjct: 2996 LSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   EC    V  P   I WY NG+ +  ST ++ 
Sbjct: 3054 VPPSIKDHDSESLSVVNV---REGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEI 3108

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 3109 LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3148



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 104/477 (21%), Positives = 174/477 (36%), Gaps = 55/477 (11%)

Query: 99   PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            P P ++W +   PL   +K  +      G   L I +    D G YTC A N+ GE    
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLIL----PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2860

Query: 159  ----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                V + P                 + S  +E  + G+        +  Q +   +   
Sbjct: 2861 YDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--H 2918

Query: 215  HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
            H    + ++       + ++     + +   G +    +  +      V P  I  K  N
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-----VPPSVIGPKSEN 2973

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
              +          ++SG P P ++W KN Q  I  N + +I      TL++   + SD G
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQP-IKLNTNTLIVPGGR-TLQIIRAKVSDGG 3031

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERIEISEKALAPQ 393
             YT +A N  G       L V  P    ++D  S+ ++    RE T   +E    A+ P 
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSLECESNAVPPP 3089

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
             +   ++     G+M      +T   + E+   + D Q+   +  K  V+++G +     
Sbjct: 3090 VITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVSDTGQYVCRAI 3133

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV               +G       LNV     +  P+      T++     PV L   
Sbjct: 3134 NV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS----NPVTLTCD 3174

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C A N+ G
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 4432 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 4482

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 4483 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 4531



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C+  G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 1662 ECKAAGNPSPILTWLKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 1718

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  I
Sbjct: 1719 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 1776 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 1812



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 1238

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
             TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 1239 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 1296

Query: 521  RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W  +G  +    P + I  DG  + L I      D   Y C A N AG+T  +  L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 14/157 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA----EISVK 3137
            I WF +G  +E++  IR +   G   L+IL  +  ++G YSC ATN+ G+     E+ V 
Sbjct: 2607 ITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVY 2664

Query: 3138 L-ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +   ++K     P  +   + ++ +K   +   EC    +  P   + WY +GQP++   
Sbjct: 2665 IPPIINKGDLWGPGLSP--KEVK-IKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDD 2719

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +   ++ G   L I   Q  D+G Y C A N  GED
Sbjct: 2720 HVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGED 2754



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 62/288 (21%), Positives = 104/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 4132

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 4133 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4192

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 4193 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 4250

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 4251 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 4303

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +   G++ V+ P
Sbjct: 4304 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 3515

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 3516 SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3569

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 3570 PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 3608



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +  S  IR + A G V+  I+  + +D   Y+C A+N+ G    
Sbjct: 3367 TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYTCVASNRAGVDNK 3424

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L+            T  I  ++    G S    C       P M   W  +GQP+  
Sbjct: 3425 HYNLQVFAPPNMDNSMGTEEITVLK----GSSTSMACITDGTPAPSM--AWLRDGQPLGL 3478

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + TVS  G +VL +   +  DSG+Y C A N+ GE
Sbjct: 3479 DAHL-TVSTHG-MVLQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 17/203 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +L+IL T+ TD G Y C A N  G A+   ++ +       G K    T + N       
Sbjct: 2927 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN------- 2979

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                  C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C
Sbjct: 2980 NFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTC 3035

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----E 3280
             A N+ GE   + ++  Y    +     +  S+  +RE  S+    +     P      +
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3095

Query: 3281 PPKFITQIQDVTKLVEGQSAHFE 3303
              + IT+   V  L +GQ  H +
Sbjct: 3096 NGRMITESTHVEILADGQMLHIK 3118



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 64/257 (24%), Positives = 98/257 (38%), Gaps = 22/257 (8%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P + W +K +P++  +   +R    +G   L I      D   Y+C A N  G A 
Sbjct: 2222 GIPPPNLIWKKKGSPVLTDSMGRVRI--LSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279

Query: 157  ----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
                  VYI+P                R  S ++E +  G    T    +    +    G
Sbjct: 2280 KEYNLQVYIRPT-ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG 2338

Query: 213  TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES-DVQISTEIDRSLGPVSPPKIA-- 269
             +            E  +L+  +   S T RYV  + +V   T+    L   +PP I   
Sbjct: 2339 VEILD---------EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389

Query: 270  -QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             + P N  + E        + SG P P +TWFK+G  +  SN   I++      LR+  T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQT 2447

Query: 329  QKSDSGHYTLLAENPNG 345
               D+G YT +  N  G
Sbjct: 2448 TMEDAGQYTCVVRNAAG 2464



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 3728 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 3784

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 3785 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 3883



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           + ES +  L I  VTLSD G   C+A + +G    Q   +V E      P  ++  + + 
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE-----PPPVIQVPNNVT 530

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V  GE  VL    +      +TWQ++   +      RI T    S L++   K +DA  Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEY 589

Query: 562 QCTAQNVAGSTA 573
            C   +  GS+A
Sbjct: 590 HCMVSSEGGSSA 601



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 260  LGPVSPPKIAQKP--RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            L  + PP I  +    + K++E        +++GNP P +TW K+GQ L     H II+ 
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS- 2530

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L++ N Q   +G YT LA +P G
Sbjct: 2531 -GGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 86/218 (39%), Gaps = 35/218 (16%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            ++ IK       E     I  ++L   W KDG+P+++   +    N G+  L IK   + 
Sbjct: 2683 EVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQIS 2738

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEV 1037
            D G YTC A N  G+     ++ I          Q P   +K+  + +     +  E + 
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI----------QVPPSFQKLWEIGNMLDTGRNGEAKD 2788

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD 1097
             I   P                S + E    P   LT    WY +G  +TS++++     
Sbjct: 2789 VIINNP---------------ISLYCETNAAPPPTLT----WYKDGHPLTSSDKVLILP- 2828

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G   L I   + ED+G YT VA N AGE  L   + V
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 74/293 (25%), Positives = 118/293 (40%), Gaps = 46/293 (15%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   + WY +G+ L+      + ++ G  TL + +    D+G YTC A N  GE      
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGEDELDFD 2759

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            V            Q P   + L +I N+ D             TGR  E     KD++ I
Sbjct: 2760 V----------NIQVPPSFQKLWEIGNMLD-------------TGRNGEA----KDVI-I 2791

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +     + E +  P       + W+ +G  + +S ++  +   G  VL+I   K  D+G 
Sbjct: 2792 NNPISLYCETNAAPPP----TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGR 2845

Query: 3121 YSCRATNKWGQ--AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            Y+C A N+ G+   +  V++      KG        +  +      +SA  EC  +    
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLV----NKSALIEC--LSSGS 2899

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P  +  W  +GQP+      K +S+    +L I  TQ  D G YVC A N  G
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAG 2950



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 66/168 (39%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 4012 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4069

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 4070 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 4121

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L IA+ Q  D+G Y C A N  G   T   +  +
Sbjct: 4122 SIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 3236 YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 3287

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 3288 ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 4431

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG P+T+S ++  I   G V L I   + EDAG YT  AVN+ GE      
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVL-ILPGGRV-LQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862

Query: 860  IRVAARSTVT-ADLGIPEQ 877
            +RV     +  A+  +PE+
Sbjct: 2863 VRVLVPPIIKGANSDLPEE 2881



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   N   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 4404

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 4405 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 1311

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 1312 PGISILEDG-TLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            ++   EC++  +  P   V W  +G PL+ K +   I D G++ +    ++  D+G Y+C
Sbjct: 2308 KSISLECEVQGIPPPT--VTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSDTGRYVC 2363

Query: 4049 RATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
             A N+ GM + K  +     P I+ + + P+++  +EK
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 4194 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 4249

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 4250 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 4300

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V     I        P      P N  
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWI 4360

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 4361 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 4417

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 2104 PNIMGEEQN 2112



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 18/164 (10%)

Query: 3079 SMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            S  + W+ +G+ +++   +  + A G   L+I   + +D+G Y+C A+N  G+ E+   +
Sbjct: 2703 SASLSWYKDGQPLKSDDHVN-IAANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV--PVD-------DPDMKIEWYHNG 3189
                    QK      I N+  L  G++   +  ++  P+         P   + WY +G
Sbjct: 2761 NIQVPPSFQK---LWEIGNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG 2815

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+  S ++  +   G  VL I   +  D+G Y C A N+ GED
Sbjct: 2816 HPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 3255 DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 3312

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            D+G YTC ATN  GE      L V     +     +    EK+  L DTS
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTI---RGNKDEAEKLMTLVDTS 3359



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  +  N     GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 4402

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  N   I  SHR R   + G + ++    K  D+G Y C A+N  G  + 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQ 692

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            +  L  ++  K         +Q+   +  G     EC    +  P +K  W+     +R 
Sbjct: 693  NSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGIPPPQVK--WFKGDLELRP 744

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLE 3250
            ST +  + D    +L I  TQ+ D+G+Y C A N+ G    + T++  G   V+++
Sbjct: 745  STFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD-VGSPPVFIQ 797



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 1170 PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 1268

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 1269 ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 1308

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 1309 GREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 1368 TNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 4078 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 4131

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 15/197 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP    V  ++  ++ G+ A     +I   D ++   W  N + +  +   R +  
Sbjct: 515  DVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLT--WQRNDRDVRLAEPAR-IRT 570

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               + LE+   K  D+G Y C  +++ G +  SV L        Q+P   T +   +   
Sbjct: 571  LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV------QEPPKVTVMPKNQSFT 624

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G      C+      P  KI W  N   +  S R +  SD    + + A     D+G Y
Sbjct: 625  GGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAA---PKDAGIY 679

Query: 3223 VCRAYNKYGEDFTRATI 3239
             C A N  G D   +T+
Sbjct: 680  GCLASNSAGTDKQNSTL 696



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PP    +P   +   G      C  TG+PKP++ W +N   IV   RY++T DG
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 4429 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 4489 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 4544

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 4545 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGK 875



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 756  LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 809

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 810  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 870  ENQFGKIQSETTVTVTG 886



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 789  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 849  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 1371 SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDA 1426

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST-QNEAG--LEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +   NE    L +   LE + K      + 
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 1486

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 1487 WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C        A+T    G  I+ S +++Y++      
Sbjct: 1546 PSIKGGNVTTDI-SVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 1604

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 1605 IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++ +    + G   L +      D G Y C A +  GE
Sbjct: 1664 KAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV      +L++      D+G YSC+A N  G ++  
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVN--NGKILKLFRATPEDAGRYSCKAINIAGTSQKY 1443

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +           T+  N   +   +    EC V     PD  I W+ +G+P+   
Sbjct: 1444 FNIDVL----VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLG 1497

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 1498 DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +    G  I  E  ++ +  PT  + W+K+G  +   ++   I   G+I L + ++++ D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSD 2357

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
            +G Y C AV+  G+ + K  L V    +I    + PE +  +++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 35/210 (16%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++++  N     E     +  P   + W ++G P+++ + +    + G+  L +K    
Sbjct: 2682 KEVKIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQI 2737

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G YTC A N  GE      + +Q   S Q        L +I  + D+ R    +DV 
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ-------KLWEIGNMLDTGRNGEAKDVI 2790

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +            N P  L         C     P P +   WY +G  L S  +     
Sbjct: 2791 I------------NNPISL--------YCETNAAPPPTL--TWYKDGHPLTSSDKVLILP 2828

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
              G   L I     ED+G YTC A+N  G+
Sbjct: 2829 --GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 57/266 (21%), Positives = 102/266 (38%), Gaps = 11/266 (4%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            L GNP P   W +  A L++    ++R      D SL I+++   D GEYTC A N  G 
Sbjct: 914  LAGNPIPERRWIKNSAMLLQNPYITVR-----SDGSLHIERVQLQDGGEYTCVASNVAGT 968

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               +  +                    +  T+  KA G    +   S++ + ++ ++   
Sbjct: 969  NNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF 1028

Query: 215  HSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
             +  D    V +       E     + T  Y  +  VQ++  +   +          KP 
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYA-KRKVQLTVYVRPRVFGDQRGLSQDKPV 1087

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSD 332
               +  G +     ++   P P +TW K  Q +   S +H  + + +   +++  T+ SD
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSD 1144

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESP 358
            SG Y  +A N  G +  +  L V  P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVP 1170



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 3652 VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 3710 NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 3759

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 3760 YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 3801



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 3952

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 3996



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +G  +  S+ +R +   G  +L ++ T   D+G Y+C   N  G+      L  +
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P        +E +K  +      T     +P  +I W+ +GQP++       +
Sbjct: 2476 ------VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII 2529

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S   F  L I   Q   +G Y C A +  G      ++N +
Sbjct: 2530 SGGRF--LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2568



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  EC+   V      + W+KNG+ +T       + D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHL 3145



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 3299

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+  L 
Sbjct: 3300 NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTLV 3356

Query: 1960 DDS 1962
            D S
Sbjct: 3357 DTS 3359



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 4252 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 4306

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 4307 VN--GHSELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     S+ +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 4400

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     ED+G YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1385 CQATNQLGEAVTSCALRVIAKKDLILE 1411
            C ATN+ G    S +L + +   + LE
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 4364 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 4419 CVATNEAGVVERSMSLTLQS 4438



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    + KN  F  G          G P P ++WT     +V  ++Y M     T D +
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM-----TSDGT 665

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L IK   P D G Y C A N  G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAG 688



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I +  G     E  ++ I   T  V W+KDG P+  +  +    + G++ L +K++ V 
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI-LQLKNIHVS 2356

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            D G Y C A N  G      +L++     II   + P  +  ++
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G  +L I  V   DAGHYTC A N  G ++TS  LT+
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 1252 TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 1305

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 1306 ELTGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPII 1392



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 3676

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++ N    D+ +YT +A N  G       L V  P
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 3712



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 4419 CVATNEAGVVERSMSLTLQSPPIITLE 4445



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 4429 ERSMSLTLQSPPIITLE 4445



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 48/170 (28%), Positives = 73/170 (42%), Gaps = 20/170 (11%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDI---------IDESVTIKPRFVTRPKSIE 1454
            AK   IL+  H   L+ I ++ DT RY    +          D SV   P  +   +S E
Sbjct: 2336 AKGVEILDEGHILQLKNI-HVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE 2394

Query: 1455 N--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            N  V+E   V   C+   +   +  + WFK+G PV++ +  R +   G   L ++    E
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPS--ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTME 2450

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            D+G YTC   N  G +     L+      IV     E  LE ++V E +S
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLVPPHIV----GENTLEDVKVKEKQS 2496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632  RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 3429 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 3485

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
              G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 3486 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 3518

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 3519 FILKVLEPPHINGSEEHE 3536



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 3605 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 3655

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 3656 LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 3700



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 3766

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 3767 F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 12/174 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C ATN  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 1188

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 1189 DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 1244

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P
Sbjct: 1245 NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKP 1296



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 1579 ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 1635

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +  I+  
Sbjct: 1636 YVPPMIEGNLATPLN--KQVVIAHSLTLECKA--AGNPSPILTWLKDGVPVKANDNIRI- 1690

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 1691 -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG PV  S+ +      G   L +   T+ DAG YTC   NA G+      L+++
Sbjct: 2418 ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475

Query: 1003 TKKDIIAES 1011
                I+ E+
Sbjct: 2476 VPPHIVGEN 2484



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 3257 SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++  L D S
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTLVDTS 3359



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 1216

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 1217 HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 1256



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T   ++ S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 1496

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 1497 GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I V  G  +  +C V+ +  PT  + W  +G P      V  L++ G I L +  I+  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GHI-LQLKNIHVSD 2357

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
             G Y C A N  G       ++  A   I+   + P+ +S
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS 2397



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 3261 GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 3319 CVATNPAG 3326



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 4131

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 4132 --SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P+ +    N     G+ V + C     G    ++ W  N   I   HR+R   +
Sbjct: 606  LTVQEPPKVTVMPKNQSFTGGSEVSIMC--SATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI-AKKDLILESQHPSGLEKIQY 1423
                 L + +  P+D+G+Y C A+N  G    +  LR I A K ++++S+    L  I  
Sbjct: 664  G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITV 720

Query: 1424 LE 1425
            +E
Sbjct: 721  ME 722



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 714 ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 769

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 770 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 826

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 881

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 938

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAG 967



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 1351 YNLKVHVPPVIKDKEQ-------VTNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 1400

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 1401 VTESSTIQTVNN--GKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+  IR + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 1725 YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLIDE 1777

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 1778 RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 1813



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEK 2092

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 2093 QRDIDLRV 2100



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 633  VYPPPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V+ PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTN--TLIVP 3015

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            G  +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   V  EC  E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 3071 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 3127 QYVCRAINVAGRD 3139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LEC    +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3126

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 4433 SLTLQS 4438



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 860  IRVAARSTVTADLGIPEQRRYI 881
            + V     +  +L  P  ++ +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVV 1654



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ + + +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 2003

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 2004 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 2053

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +   Q  D+G Y C A N  GE
Sbjct: 2054 SFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVNAAGE 2091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G+ +  EC+++ +      V W K+G P+ I  +   I D G++ L + ++   D+G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSDTG 2359

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             Y C AVN+ G  +    L+  +   I+    N    E I V+E  S
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSII---GNHRSPENISVVEKNS 2403



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G++   E ++  +  PT  V W KDG P+  +  +  I + G++ L + ++   D G Y 
Sbjct: 2307 GKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGV-EILDEGHI-LQLKNIHVSDTGRYV 2362

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
              AVN  G       + V A  ++  +   PE    +EK
Sbjct: 2363 CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   EC     P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 3073 EGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 3244 PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 3301

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 3302 STLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)

Query: 3047 PPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP  +   K+ ++ + +      EA  +P  D    I W  +G+ I  S R R V + G 
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPD----ITWHKDGRAIVESIRQR-VLSSGS 4132

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LK 3162
              L+I   +  D+G Y+C A N  G +  S KL     +    PR    I++ EG   + 
Sbjct: 4133 --LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL-----TVHVPPR----IRSTEGHYTVN 4181

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +   A   C    +  P   I W  +   + +     T   +G ++L+    +  DSG Y
Sbjct: 4182 ENSQAILPCVADGIPTP--AINWKKDNVLLANLLGKYTAEPYGELILENVVLE--DSGFY 4237

Query: 3223 VCRAYNKYGED 3233
             C A N  GED
Sbjct: 4238 TCVANNAAGED 4248



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 788  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 900

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 901  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 956

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 957  EYTCVASNVAG 967



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 1351 YNLKVHVPP 1359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 84/375 (22%), Positives = 143/375 (38%), Gaps = 32/375 (8%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            +NI V E   V   C  E  G P   I WF +G P +  + V  L+  G   L +     
Sbjct: 2394 ENISVVEKNSVSLTC--EASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTM 2449

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+YTC   N  G       ++      IV E+ L      EK        ++  P  
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E       + + + ++H +    G RF  ++   + P      Y      P+GH+ R+  
Sbjct: 2510 EITWHKDGQPLQEDEAHHI--ISGGRF-LQITNVQVP--HTGRYTCLASSPAGHKSRSFS 2564

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVND------FGEDFTKATISCKKLPDIILQNQVPR- 3935
               FVS  I  V ++ + E +   +N           +  ATI+  K    +  N+  R 
Sbjct: 2565 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI 2624

Query: 3936 --GMKRSEALTQMEATIKKYTSEVYLTEDDL---YDVDKKQPP------RFVTQIQSQTS 3984
              G +  + L   E    +Y+        ++   Y+V    PP       +   +  +  
Sbjct: 2625 LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEV 2684

Query: 3985 LVEMETT-KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
             +++  T   EC+   +  P+  + W+ +G+PL   +    I   G+  +        D+
Sbjct: 2685 KIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVN-IAANGH-TLQIKEAQISDT 2740

Query: 4044 GEYLCRATNLYGMDE 4058
            G Y C A+N+ G DE
Sbjct: 2741 GRYTCVASNIAGEDE 2755



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 4429 ERSMSLTLQS 4438



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 4432 MSLTLQSPPIITLE 4445



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 87/402 (21%), Positives = 156/402 (38%), Gaps = 41/402 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 791  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 966

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 967  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 1023

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDQRGLS 1082

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 1137

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +    DSG+Y C A N+ G    + +L       I R  ++
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 1544 IPPSIKGGNVTTDI----SVLINSLIKLECETRGLPMP--AITWYKDGQPIMSSSQALYI 1597

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 1598 -DKG-QYLHIPRAQVSDSATYTCHVANVAG 1625



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 2063

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 2064 GGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V  GK+   EC+V+ +  P   + +  +G  L  A    I  D G++ L +++    D G
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTG 2359

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
             Y   A+N  G       ++V A  SII   + PE +  + +   +   +   IP P
Sbjct: 2360 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 3261 GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDT--QNEQAIEQIQLLEDAA 1295
              A N  G        R+   +  VT T   N+   E++  L D +
Sbjct: 3319 CVATNPAGEED-----RIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 3359



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S      G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 4399

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL+L+S   +   +   +  S        V + V + P+ +T +      + G      C
Sbjct: 575  SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMC 633

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P  ++ W  N   +   HRYR ++D     L I     +D+G Y C A N+ G
Sbjct: 634  SATGYPKP--KIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 1927 QAVSSIRLN-VQSKESIIRDSQHESALEKIQYLE 1959
                +  L  +++ + ++  S+   AL  I  +E
Sbjct: 689  TDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 897  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 952

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 953  QDGGEYTCVASNVAG 967



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 1224

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
             +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 1225 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 1907

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY + + +
Sbjct: 1908 QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNRLL 1961

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1962 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1998



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 11/161 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +   + +D+G Y+C A N  G+ +  + L   
Sbjct: 2043 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVY 2101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 2102 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 2152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S+    VL I   Q  D+G Y C A N  G+      +N +
Sbjct: 2153 SE-NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 54/211 (25%), Positives = 82/211 (38%), Gaps = 34/211 (16%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            S K V+IK       E     +  A+L   WY + +PLKS        N G   L I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASLS--WYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSA 1702
               D+G YTC         V S IA    +    +  Q   +  +L ++ +     R+  
Sbjct: 2736 QISDTGRYTC---------VASNIA-GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
              +VI   P+           E  AA           P   + W ++G P+ +S+++  +
Sbjct: 2786 AKDVIINNPISLY-------CETNAA-----------PPPTLTWYKDGHPLTSSDKVLIL 2827

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G   L +     ED+G YTC A+NE GE
Sbjct: 2828 P--GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2856



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633  VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 3052 VYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTH-VEI 3108

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
               G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 3109 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 3154



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 3126

Query: 842  SYTVRAVNKLG 852
             Y  RA+N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             NL +     I          EK+  L D S
Sbjct: 3332 FNLNVYVTPTIRGNKDE---AEKLMTLVDTS 3359



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS+ I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 4403

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 4404 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 4461

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 4462 QATGEPQPTIT 4472



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 18/270 (6%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 1102 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATNIAG 1157

Query: 154  EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
                +V +                        +   A GT       S+    +   +G 
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 1216

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
             H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 1217 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 1269

Query: 272  PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
            P N+  QE    Q   F     G P+P + W  NG+ L    +  I    + T L + + 
Sbjct: 1270 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEDGTLLVIASV 1328

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               D+G Y  +A N  G       L V  P
Sbjct: 1329 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 22/283 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 1225

Query: 131  LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
            L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 188  H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                A GT        + T K  + NG + +  +       +  LL   S        Y+
Sbjct: 1286 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337

Query: 246  GESDVQI-STEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
              +  +  +TE   +L    PP I  K +  N  +          ++ G P P + W+K+
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 1398 NVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ I+     + +     +V  I   + +++G Y C A N  G    
Sbjct: 1759 TGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKK 1816

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 1817 EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 1865

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 1866 PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 724  AVLHVTPRATIE 735
              LHV    ++E
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQIS--DTGRYTCVAVNAAGEKQR 2094

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 2095 DIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P+++I++   S   EC +  +   +  V W  +G PL+    V+ +++ G  IL++  ++
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GH-ILQLKNIH 2354

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
              D G Y C A N  G       L V     II   + P +
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            +L++     +D+G Y C A N  G  +    L      S     R   +I  +E  K+  
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE--KNSV 2404

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   E + +P+      I W+ +G P+  S  ++ +S  G  +L +  T   D+G+Y C 
Sbjct: 2405 SLTCEASGIPLPS----ITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCV 2458

Query: 3226 AYNKYGED 3233
              N  GE+
Sbjct: 2459 VRNAAGEE 2466



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 55/215 (25%), Positives = 77/215 (35%), Gaps = 34/215 (15%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+    +   EC  E Y  P+  + WY +G+ L+S      + + G   L I      D+
Sbjct: 2685 KIKVNNTLTLEC--EAYAIPSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDT 2740

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G YTC A N  G+      +N+Q   S          L +I  + D  R   A       
Sbjct: 2741 GRYTCVASNIAGEDELDFDVNIQVPPSF-------QKLWEIGNMLDTGRNGEA------- 2786

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
                         +V   +P+ L         PT+   WY +G P+      K     G 
Sbjct: 2787 ------------KDVIINNPISLYCETNAAPPPTL--TWYKDGHPLTSSD--KVLILPGG 2830

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
              L I  A  ED G Y C A N  GE      V+V
Sbjct: 2831 RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 3122

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 3123 SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 3170

Query: 3548 LTPEAESGNPP 3558
            LT +A +G PP
Sbjct: 3171 LTCDA-TGIPP 3180



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 785  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 843

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 844  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 1006 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 1063

Query: 724  AVL--HVTPR 731
              L  +V PR
Sbjct: 1064 VQLTVYVRPR 1073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTV-NNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 860  IRVAARSTV 868
            I V    T+
Sbjct: 1446 IDVLVPPTI 1454



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+  +   +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 1510

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1952 ITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 2010 VAPSISGSN 2018



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            +++  + V   P      + PT++  + G+S   EC ++  P P   V W  +G  L   
Sbjct: 2279 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKA 2336

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                  ++     L +  ++  D+G Y C A+N  G       L+V +  SII    H S
Sbjct: 2337 KGVEILDEGHI--LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII--GNHRS 2392

Query: 1951 ALEKIQYLEDDS 1962
              E I  +E +S
Sbjct: 2393 P-ENISVVEKNS 2403



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +C    V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 3124

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 3125 TGQYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 3071 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 3126

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 3127 QYVCRAINVAG 3137



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626  PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 3661

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 3662 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 3529 EGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS 3588
            EG  + IA     +G   T    +E   PP     P+++ ++    A   C +I   D +
Sbjct: 494  EGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550

Query: 3589 MRVEWFHNGKP--LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            +   W  N +   L   +R++T+ +     LE+  V   DAG Y C  ++  G +  S  
Sbjct: 551  LT--WQRNDRDVRLAEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVF 605

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTE 3670
            L V+    + + P+  S F  G+E
Sbjct: 606  LTVQEPPKVTVMPKNQS-FTGGSE 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PPK     K+ +      V   C       PK +I W  N   +   HRYR   D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGY--PKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              +L I     +D+G Y C A N  G D   +T+   + P +++
Sbjct: 664  -GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 916 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 972

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 973 TSVVVHVLP--TIQHGQQILSTIEGI 996



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P+++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 1446 IDVLVPPTIIG-----TNFPNEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 1496

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 1497 GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 1405 KKDLILESQ-HPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            +K +I ++Q   +GL +         +KK    + +V + P   +   S   V++ + V 
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVA 1845

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
             +C    +   N  + W K+ QPV        I   G V L I   + ED+G YTC A N
Sbjct: 1846 LQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902

Query: 1524 LVGTDEVSCRL 1534
              G  +   +L
Sbjct: 1903 AAGETQQHIQL 1913



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S P   + W+KDG P+ ++  I  +   G  +L I++ + ++AG Y+  A N+ GE I  
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658

Query: 858  ASIRV 862
              ++V
Sbjct: 2659 YEVKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+G  L +   ++     G  TL I + + D++G Y+C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2732 IKI 2734
            +K+
Sbjct: 2661 VKV 2663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +C    V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 860  IRVAARSTV 868
            + V    T+
Sbjct: 3334 LNVYVTPTI 3342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 3829 GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 3886

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 3887 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 3945

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 3946 ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 3998

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 4056

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 4057 MCVAQNPAGTALGKIKLNVQVP 4078



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 4126

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 4127 VLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 791  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 850  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 994  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 1003 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 1058

Query: 154  EA----ICSVYIQP 163
             A      +VY++P
Sbjct: 1059 YAKRKVQLTVYVRP 1072



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/179 (21%), Positives = 72/179 (40%), Gaps = 7/179 (3%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W   G  +      R     G   L+I   + +D+  YSC A+N  G A+    L+    
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY-- 2287

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             +       +H   I  +  G+S   EC V  +  P   + W  +G P+  +  ++ + D
Sbjct: 2288 IRPTITNSGSHPTEII-VTRGKSISLECEVQGIPPP--TVTWMKDGHPLIKAKGVE-ILD 2343

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
             G  +L +      D+G YVC A N  G    +  ++ +    +      P++++ + +
Sbjct: 2344 EGH-ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2401



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E  + P  TI WF +G  + +    R     G   L IL    +++G Y C ATN+ GE 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 2194 VNTCTLKV 2201
            +    +KV
Sbjct: 2656 IKHYEVKV 2663



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIH--FETRIE----PVGDPTMKIEWLKNGQSI 679
            P GEEDR++    ++ P       E  K+    +T I       G P  +I WLKNG  +
Sbjct: 3324 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 3383

Query: 680  EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
              SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 3384 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 3421



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 3728 KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 3784 MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 3795

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 3796 IDLQVHVPP 3804



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 4151 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 4204

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 4205 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 1253 EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 1304

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 1305 RELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 1346



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 1259 QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 1312

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 1313 GISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 1354



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 653  KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
            K+  ETR    G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC 
Sbjct: 1566 KLECETR----GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCH 1619

Query: 713  AVSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
              +  G AE    + V     IE     P   Q +
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 1654



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284  QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
            + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 1623

Query: 344  NGCIVTSGYLAVESP 358
             G    S ++ V  P
Sbjct: 1624 AGTAEKSFHVDVYVP 1638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+ + +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 2003

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 2004 YSLQVHVAP 2012



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKDG P+     ++   N     L I+   V D G YTC A N  G+   + N+ I
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ WY +G+ + S + +    + G+  L I   +  D+G YT VA N AGE +L   + +
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            +   S       + L+E          +  M       ++K V +   +NP        I
Sbjct: 2763 QVPPSF------QKLWE----------IGNMLDTGRNGEAKDVII---NNP--------I 2795

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C       PT+   W+ +G  +T  S  K     G   L I  A   D G YT  AV
Sbjct: 2796 SLYCETNAAPPPTL--TWYKDGHPLT--SSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851

Query: 1256 NHLGSAHTSAIVRVI 1270
            N  G       VRV+
Sbjct: 2852 NEAGEDSLQYDVRVL 2866



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 3253 PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 3309 ALTSDTGKYTCVATNPAGE 3327



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 3469 WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 3526

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 3527 PHINGSEEH 3535



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 3523 VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 3580

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 3581 GEVLRISTAQVEDTGRYTCLASSPAGD 3607



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 3767

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 4197 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254

Query: 1134 TV 1135
            TV
Sbjct: 4255 TV 4256



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 4268 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 4321

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G     G
Sbjct: 4322 DSGTYVCTAENSVGFVKAIG 4341



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 4451 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 4506

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 4507 FECVARNLMG 4516



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  KI W  N+  +    RY+ T D +   L I +   +D+GIY C A+NS G+   + +
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 2863 LR 2864
            LR
Sbjct: 696  LR 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 994  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 1049

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 1106

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 1107 PPPIITWAK 1115



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 265  PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP I     P    +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 1509

Query: 323  LRVRNTQKSDSGHYTLLAENPNG 345
            L ++N +++D G Y     N  G
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 7/149 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            SH   I+   G +I  EC V+    PT  + W  +  PL      +   D  ++ L + +
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKN 2352

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
             +  D+G Y C A N  G       L      +I  + + P+    +  VE+   +   +
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE---NISVVEKNSVSLTCE 2409

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEG 2926
                 +P   + K  W + ++   +++ G
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSG 2438



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   + W+ +G P++     +     G   L IL A  ++ G Y C ATN  GE +    
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 2067 VKV 2069
            VKV
Sbjct: 2661 VKV 2663



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 3069 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 3124

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 3242 QVPPSVAGAEI 3252



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 3439 SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 3494

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 3535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 4100 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4154

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSS 4157

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 4158 STSTKLTVHVPPR--IRSTEGH 4177



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 4194 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 4251

Query: 997  ANLTI 1001
             +LT+
Sbjct: 4252 VSLTV 4256



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 4375 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 6/142 (4%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
            Q  + +    L I++    DEG Y+C+A +SAG         V++P     +P      +
Sbjct: 474  QYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVP-----NN 528

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V  G+ A     I S +   + W R    +    +   I    N  L + +    D G
Sbjct: 529  VTVTPGERAVLTCLIISAVDYNLTWQRNDRDV-RLAEPARIRTLANLSLELKSVKFNDAG 587

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C  ++  G    S  L V+
Sbjct: 588  EYHCMVSSEGGSSAASVFLTVQ 609



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK ++ W  N + I  S+R     D     L +K   P+D+G Y C A N  G    +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 1798 STL-FVQSKASLQLESQHESALQKIQQLE 1825
            STL ++++   + ++S+   AL  I  +E
Sbjct: 694  STLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 775  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449

Query: 1003 TKKDII 1008
                II
Sbjct: 1450 VPPTII 1455



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 3833 ITQIKSHTVE----ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            IT   SH  E      + +  EC V+    P   + W ++G  L        + D G + 
Sbjct: 2292 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI- 2347

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGM 3937
            L +  ++  D+G Y+C AVN  G    K  +S    P II  ++ P  +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2396



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            P   + WF +G  L      R     G   L IL   E+N+G Y CVATN+ G
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            DV    P+   C       PT+   W+ +G P  +  +V  L   G   L I      DA
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDA 2843

Query: 3766 GEYTCRATNKWG 3777
            G YTC A N+ G
Sbjct: 2844 GRYTCVAVNEAG 2855



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL TL D+ +
Sbjct: 3334 L------NVYVTPTI-RGNKDEAEKLMTLVDTSI 3360



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 3581

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAG 3606



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 3685

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 3686 -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3744

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 3745 TWRKDGAVLAGNHARYSILENGFLHI---QSAH 3774



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L IA V+  D+G YT +A N AG +  S  +TV 
Sbjct: 4110 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAI 4187



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP + Q P N  +  G  A     +       +TW +N + +  +    I T  N  +L 
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLE 577

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
           +++ + +D+G Y  +  +  G    S +L V+ P +  V  +   +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSF 623



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 790  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 847  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 897  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 951

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 952  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 1236

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQE 1260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFET-RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            VY PP     L +    +    H  T   +  G+P+  + WLK+G  ++A+         
Sbjct: 1635 VYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR--IEA 1692

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
            G   L+++S    D G+Y C A S  G  E K  + V     IE
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 1736



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 2039 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDID 2097

Query: 860  IRV 862
            +RV
Sbjct: 2098 LRV 2100



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 2099 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 2156

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              + ++     +QD+G YTC A +  G  E
Sbjct: 2157 SVLKIE--DAQVQDTGRYTCEATNVAGKTE 2184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R+  NI  VE  +V L C     G     + WF +G P+   +  R         L L+ 
Sbjct: 2391 RSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQ 2446

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
               ED+G YTC   N  GE      L V+    ++ E+
Sbjct: 2447 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN 2484



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W+KDG P++ S+ +  I + G + L +M    EDAG YT    N  GE
Sbjct: 2414 PLPSITWFKDGWPVSLSNSV-RILSGGRM-LRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P+  + WYKDG+P+ +   +    N G+ +L I   +  D G YT  A N  GE
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGE 2753



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG P+ +S ++      G   L I    V DAG YTC A N  G+ +   ++ ++
Sbjct: 2811 WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+ N++EG     EC    +  P +T  W+ NG+ I          D G + L I     
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPVIT--WYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2177 EDSGTYMCKATNKLG 2191
             D+G Y+C+A N  G
Sbjct: 3123 SDTGQYVCRAINVAG 3137



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 3147 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
               L +      DSG YTC A +  G A+
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 3449 KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 3504

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 3505 TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3536



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 3769

Query: 325  VRNTQKSDSGHYTLLAENPNG 345
            +++   +D+G Y  +A N  G
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAG 3790



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 4106 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162

Query: 860  IRV 862
            + V
Sbjct: 4163 LTV 4165



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 4364 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4418

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 4419 CVATNEAGVVERS 4431



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 4427 VVERSMSL 4434



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 4433 SLTLQSPPIITLEPVE 4448



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKI 876



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + W KD R +  S+ +T F N G + + I+S  + DAG Y C A N+ G
Sbjct: 1952 ITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +  A  +DTG YT  A
Sbjct: 2029 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVA 2085

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 3261 GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTS 4160

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 4161 TKLTVHVPPRIRSTEGHYTVNENSQAI 4187



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP--FATGSR 3743
            T  D    PP   +++ +N+ V  G      C +    D    + W  N R    A  +R
Sbjct: 512  TFFDVSEPPP--VIQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPAR 567

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            + TL +   ++L++  +   DAGEY C  +++ GS+  +  +T
Sbjct: 568  IRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 700  EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 754

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 755  GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 798



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 1236

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTV 1264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++ +LL SG    T  + G + +DI      
Sbjct: 1929 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNRLL-SGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1985 DAGIYKCVAINSAG 1998



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 1176 KPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +P      S+P    V+ GK+I LEC ++ +  PT  V W  +G  +      +   +  
Sbjct: 2289 RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGH 2346

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
             + L  IH   +DTG Y   AVN  G       + V     I+ + ++ + I  ++
Sbjct: 2347 ILQLKNIHV--SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+ E QS    C +   P P   + W+ +G+ LQ    +   +   F  L I  V    +
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPE--ITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2545

Query: 1915 GEYTCKAINNLGQAVSSIRLNV 1936
            G YTC A +  G    S  LNV
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNV 2567



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P D+ +  NS     C       ++  + WF +G PL +   ++ +   G   L+I    
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPAT--ITWFKDGTPLESNRNIRILP--GGRTLQILNAQ 2637

Query: 3624 QRDAGLYTCKATNRHGE 3640
            + +AG Y+C ATN  GE
Sbjct: 2638 EDNAGRYSCVATNEAGE 2654



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 51/193 (26%), Positives = 78/193 (40%), Gaps = 41/193 (21%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            P+  + W+ +G+P  +   V+   + G   L I      D G YTC A+N          
Sbjct: 2702 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASN---------- 2749

Query: 3785 ITCSAKRDIVLESQLPQGMSGEKIKE----LERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            I    + D  +  Q+P   S +K+ E    L+ GR  +A  ++ I++ P           
Sbjct: 2750 IAGEDELDFDVNIQVPP--SFQKLWEIGNMLDTGRNGEA--KDVIINNP----------- 2794

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
                  +   C       P L   WY++G  L S  +   +   G V L I     ED+G
Sbjct: 2795 ------ISLYCETNAAPPPTLT--WYKDGHPLTSSDKV-LILPGGRV-LQIPRAKVEDAG 2844

Query: 3901 EYICRAVNDFGED 3913
             Y C AVN+ GED
Sbjct: 2845 RYTCVAVNEAGED 2857



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+I++   S + E    P       + W+ +G PL +  +V  +   G  +L+I      
Sbjct: 2788 DVIINNPISLYCETNAAP----PPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVE 2841

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            DAG YTC A N  GE ++   ++V
Sbjct: 2842 DAGRYTCVAVNEAGEDSLQYDVRV 2865



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 3274 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T+  T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 3354 TLVDTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 3409

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3519

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 3520 ILKV-------LEPPHINGSEEHEEI 3538



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 3463 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 3514



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 4438 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4494

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 4495 YIADAQ---KEDTSEFECVARNLMGS 4517



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P+     KN   T G  V +  + T    P  ++ W  N   +   HR++ T D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG- 664

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
               L I  A  +D G Y C A+N+ G     S+++
Sbjct: 665  --TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI W  N   +    R+++TSD    TL + +   +D+GIY C A N  G    +ST
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 3001 V 3001
            +
Sbjct: 696  L 696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 756

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 757  -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 794  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 854  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICV 1339

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 1340 AVNEAGTTERKYNLKV 1355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAG 1345



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   P  + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNF---PNEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 1493

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 1471 VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 1527

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 1528 SNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915

Query: 1136 ETRSSID 1142
                S++
Sbjct: 1916 HEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G  + LE  +  +  PT  V W  +G P+ +    +   D G++ L +   +  DTG
Sbjct: 2304 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTG 2359

Query: 2049 TYMCKATNAVG 2059
             Y+C A N  G
Sbjct: 2360 RYVCVAVNVAG 2370



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 8/144 (5%)

Query: 3962 DDLYDVDKKQPPRFVTQIQS--QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            D  YD+    PP  +   +S    S+VE  +    C+ +  G P   + WF +G P+   
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS--GIPLPSITWFKDGWPVSLS 2430

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
            N    +   G   +       ED+G+Y C   N  G +     +     P IV ++ L +
Sbjct: 2431 NSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-E 2487

Query: 4080 HMKSIEKIREMEASWQVTPEQVVE 4103
             +K  EK + +  + +VT   V E
Sbjct: 2488 DVKVKEK-QSVTLTCEVTGNPVPE 2510



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + W+ +G  L+S    R     G   L IL    +++G Y+C A N  G+ 
Sbjct: 2598 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2655

Query: 1929 VSSIRLNV 1936
            +    + V
Sbjct: 2656 IKHYEVKV 2663



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV 3622
            +P ++ +  N++   EC    +  +S+   W+ +G+PL +   V    + G   L+I   
Sbjct: 2680 SPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2735

Query: 3623 YQRDAGLYTCKATNRHGE 3640
               D G YTC A+N  GE
Sbjct: 2736 QISDTGRYTCVASNIAGE 2753



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDL 1509
            PK ++  +    +  EC+   +  ++L   W+K+GQP+        I   G+  L I + 
Sbjct: 2681 PKEVKIKVNNT-LTLECEAYAIPSASLS--WYKDGQPLKSDDHVN-IAANGHT-LQIKEA 2735

Query: 1510 IAEDSGIYTCRAVNLVGTDEV 1530
               D+G YTC A N+ G DE+
Sbjct: 2736 QISDTGRYTCVASNIAGEDEL 2756



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/120 (30%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            EDS +Y  R  V   +  A    + L     +   +SA  EC     P P  R  W  +G
Sbjct: 2856 EDSLQYDVRVLVPPIIKGAN---SDLPEEVTVLVNKSALIECLSSGSPAP--RNSWQKDG 2910

Query: 1885 K-VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            + +L+  H    SN      L IL     D G Y C A N  G A     LNV    S+I
Sbjct: 2911 QPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2967



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 2986 CEVSGFPPPDL--SWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 3041

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 3042 GESKKKFSLTVYVPPS-IKDHDSES 3065



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 8/151 (5%)

Query: 2194 VNTCTLKVAGHRNI-ILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV---TELR 2249
            +NT TL V G R + I+  +  +G E       Q   ++ +       PP      +E  
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESL 3066

Query: 2250 GTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVP 2309
               +V EG +   EC+   V  P   I +Y NG+ +  +    I  D G + L I+    
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3122

Query: 2310 EDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
             D G+Y  +AIN  G       + V    SI
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSI 3153



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 3447 VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 3502

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 3503 KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3537



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 3674

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 3675 RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 3722



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 3979

Query: 724  AVLHV 728
              LHV
Sbjct: 3980 VTLHV 3984



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 14/133 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 4217 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 4268

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 4269 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 4322

Query: 3219 SGEYVCRAYNKYG 3231
            SG YVC A N  G
Sbjct: 4323 SGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W +N + +    R+R T D    TL I +    DAG+Y C A N AG
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V    PV  +C+    G+P   I W+ + R   +GS   T  + G I +DI+     
Sbjct: 1929 NETVLVSNPVQLECKA--AGNPVPVITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3764 DAGEYTCRATNKWGS 3778
            DAG Y C A N  G+
Sbjct: 1985 DAGIYKCVAINSAGA 1999



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 3826 VSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNEQ--PIKLNTNTLIVP 3015

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            G  +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN+ GE+   
Sbjct: 2990 GFPPPDLSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 3108 ILADGQMLH 3116



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 2996 LSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053

Query: 1003 TKKDI 1007
                I
Sbjct: 3054 VPPSI 3058



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 3272 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3331

Query: 724  AVLHVTPRATIERTSQHPETL 744
              L+V    TI       E L
Sbjct: 3332 FNLNVYVTPTIRGNKDEAEKL 3352



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 1791 LGE 1793
             G+
Sbjct: 3605 AGD 3607



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 3653 ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 3709



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 3712 PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 3768

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 3769 HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3806



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 3887

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 3888 TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 3936

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 3937 LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 3985



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 3952

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 3993



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 4260 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 4312

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 4433 SLTLQSPPIITLE 4445



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  +T +   ++   G      C       P +   W  N   I   HRYR T D   
Sbjct: 609  QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDMFIVGSHRYRMTSD--- 663

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
              L I     +D+G Y C A+N  G      TL+
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 1273 TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVT 1329

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 1330 PYDNGEYICVAVNEAGTTERKYNLKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 3510 MKV 3512
            +KV
Sbjct: 1353 LKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAG 1438



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 1671 SKKSI 1675
               S+
Sbjct: 1917 EPPSL 1921



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1946 GNPVPVITWYKDN-RLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L  +T +EG  I      E  G P   + W K G  +   S        G   L +    
Sbjct: 2203 LTQLTVIEGNLISL--LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE 2260

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
              D+  Y+C A +  G A+ +  L V  R TI  +  HP
Sbjct: 2261 KSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHP 2299



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG  + L  +      PNL   W K G  + T +  +     G   L I+     D+ 
Sbjct: 2208 VIEGNLISLLCESSGIPPPNLI--WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2265

Query: 2714 IYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            +Y+C A+N+ G A    ++++  R  +     HP  +
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W+++G P+  +  +  + D G++ L +K ++  D+G Y C A+N  G     
Sbjct: 2318 GIPPPTVTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2375

Query: 1798 STLFVQSKASL 1808
              L V +  S+
Sbjct: 2376 YDLSVHAPPSI 2386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P   + W ++G P+E++  +  +   G   L +     +++G Y+C A NE GE +
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 2963 PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GG 3017

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 3430

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 3431 FAPPNM----DNSMGTEEITVLKGSS 3452



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 3791



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 3744 ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3801

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 3802 VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 3852

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 3853 YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 4260 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 4312

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVG 4335



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 945  WLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            W ++ R V  +  +RI T  N   ++L +KSV  +DAG Y C   +  G +  S  LT+ 
Sbjct: 553  WQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 1002 -VTKKDIIAESQHPGGLEKIQYLEDASRYSK 1031
               K  ++ ++Q   G  ++  +  A+ Y K
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPK 640



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    PK+ ++   G  V   C          K+ W  N   +   HR+R   D     
Sbjct: 612  PKVTVMPKN-QSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG---T 665

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L I +   +D+GIY C A N  GTD+ +  L
Sbjct: 666  LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            +T+T+   +   + +  + A    Q  + + V   P+  R   +++   G  V + C  Q
Sbjct: 1137 ITETRTSDSGMYLCVATNIAGNVTQAVK-LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G     + W   G  +        +     +++D  +  P D+G+YTC ATN  G   
Sbjct: 1196 --GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT--PSDAGIYTCVATNIAGTDE 1251

Query: 1396 TSCALRV 1402
            T   L V
Sbjct: 1252 TEITLHV 1258



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            +L C +E  G P+  + W+ +   VT  S  +T  + G + L +  AT  D G Y+ +A+
Sbjct: 1379 NLFCEVE--GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAI 1434

Query: 1256 NHLGSAHTSAIVRVIERSDIV-TDTQNEQAI 1285
            N  G++     + V+    I+ T+  NE ++
Sbjct: 1435 NIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 1465



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   + WYKD R ++ S+ +T   N G + ++I   +  DAG Y   A+N  G      
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 859  SIRVAARSTVT 869
            S++V    +++
Sbjct: 2005 SLQVHVAPSIS 2015



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ID  V + P  +   +++ +V+  Q V   C+ + +    L   W K+G P+ +      
Sbjct: 2096 IDLRVYVPPNIMGEEQNV-SVLISQAVELLCQSDAIPPPTLT--WLKDGHPL-LKKPGLS 2151

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            I +   V L I D   +D+G YTC A N+ G  E
Sbjct: 2152 ISENRSV-LKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3694 PPRFTVE-IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP    E   +++ V E   V   C V   G+P   I W  +G+P       H ++   F
Sbjct: 2477 PPHIVGENTLEDVKVKEKQSVTLTCEV--TGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2534

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I  +     G YTC A++  G
Sbjct: 2535 --LQITNVQVPHTGRYTCLASSPAG 2557



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  + E    P+  + W+K+G  L +   +    +    TL I   +  D+G YTC A+N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASN 2749

Query: 2722 LLGE 2725
            + GE
Sbjct: 2750 IAGE 2753



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 2/72 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KDG+P+        F + G + L I +  + D G Y C A N  G A   
Sbjct: 2898 GSPAPRNSWQKDGQPLLEDDH-HKFLSNGRI-LQILNTQITDIGRYVCVAENTAGSAKKY 2955

Query: 997  ANLTIVTKKDII 1008
             NL +     +I
Sbjct: 2956 FNLNVHVPPSVI 2967



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 14/146 (9%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYVALDLLSVY 1376
            N+  V    + L C +   G     + W  N +PIK  T     P        L ++   
Sbjct: 2973 NLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTNTLIVPGGR----TLQIIRAK 3026

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              D G YTC A NQ GE+    +L V       ++      L  +   E TS      + 
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTS----VSLE 3080

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHV 1462
             ES  + P  +T  K+   + E  HV
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHV 3106



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 3073 EGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3128

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 3129 VCRAINVAG 3137



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W +N K IE+S  +      G   + I+  +  D G Y C ASN+ G+
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3232



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 3318

Query: 146  CTARNQYGE 154
            C A N  GE
Sbjct: 3319 CVATNPAGE 3327



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 3357 DTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 3412

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 3413 CVASNRAGVDNKHYNLQV 3430



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 3556 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613

Query: 860  IRV 862
            +RV
Sbjct: 3614 VRV 3616



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 3728 KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 3782

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3820



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  +G+ ++   R + ++      L+I  V   DAG YTC A N  G ++ S KL V
Sbjct: 4110 ITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 4364 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 4418

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 4419 CVATNEAG 4426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPP   VP  +VT   G +      I    D    + W +N + +  +     I     +
Sbjct: 519 PPPVIQVP-NNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEP-ARIRTLANL 574

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQ 739
           SL++ S+   D+GEY C   S  G +     L V   P+ T+   +Q
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 702  PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 757

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 758  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 799



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 1007 NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 1063

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 1064 VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 1118

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 1119 LISPFSPRH 1127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 1253

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQE 1277



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +E  P P   + WY +   +      +T N+     L +     ED+G Y+CKAIN  
Sbjct: 1382 CEVEGTPSPI--IMWYKDNVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIA 1437

Query: 1926 GQAVSSIRLNVQSKESII 1943
            G +     ++V    +II
Sbjct: 1438 GTSQKYFNIDVLVPPTII 1455



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1844 PRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            P  I   N P ++S    +    EC+++  P P+  + W+ +GK L  G       D G 
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRG- 1507

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L +      D G Y C   N  G+    I+L +    SI
Sbjct: 1508 QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 1548



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+     +   + G   L+I+ A   
Sbjct: 1650 NKQVVIAHSLTLECKAA--GNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEI 1705

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 1838 VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 1894

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 1895 RYTCVATNAAGE 1906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 1912

Query: 2199 LKV 2201
            L V
Sbjct: 1913 LHV 1915



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 2001 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 2057

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 2058 GLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 2109



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V   +PV LE     +  P++   W  +G PV            G + L +  A   DTG
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLT--WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTG 2079

Query: 2049 TYMCKATNAVGE 2060
             Y C A NA GE
Sbjct: 2080 RYTCVAVNAAGE 2091



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 2034 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVN 2087

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 2088 AAGEKQRDIDLRV 2100



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  + + Q+ + L+  +  +  CQ   +  P +   W  +G PLL K   +   +   +
Sbjct: 2103 PPNIMGEEQNVSVLIS-QAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENRSVL 2159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V  +D+G Y C ATN+ G  E    +     P I
Sbjct: 2160 KIEDAQV--QDTGRYTCEATNVAGKTEKNYNVNIWVPPNI 2197



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G ++ LEC +Q +   T  V W  +G P+          E     L L +++  D
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSD 2357

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            +G Y C A N  G       L V A   +I   + P  +  ++
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2400



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P   + W ++G P+  SN +  +   G   L +     ED+G YTC   N  GE
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P ++ +  N SA  EC  +     + R  W  +G+PLL     K +++    IL+I    
Sbjct: 2879 PEEVTVLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQ 2934

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQV 3649
              D G Y C A N  G A     L V
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNV 2960



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/71 (33%), Positives = 31/71 (43%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N   IE S+ L      G   L +      DSG YTC A N  G+A   
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236

Query: 1798 STLFVQSKASL 1808
              L +Q   S+
Sbjct: 3237 YFLSIQVPPSV 3247



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 3738 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 4165 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 4222

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 4223 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 4426


>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
          Length = 5636

 Score =  129 bits (312), Expect = 2e-28
 Identities = 107/384 (27%), Positives = 161/384 (41%), Gaps = 35/384 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  ++ A  E    G P P   W ++  P+      +    S   IL I    + D   +
Sbjct: 2885 VLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRILQILNTQITDIGRY 2942

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGT 4540
              VAEN  G+AK   NL V           VPPS     ++N+ V     + L  +V+G 
Sbjct: 2943 VCVAENTAGSAKKYFNLNVH----------VPPSVIGPKSENLTVVVNNFISLTCEVSGF 2992

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P D+ WLKN + ++ +    I+   G  TL I+ A   D G+Y C+AIN AGE++    
Sbjct: 2993 PPPDLSWLKNXQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFS 3050

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V +P       P  K  ++     E L    V EG ++   C+    P P + WYK  
Sbjct: 3051 LTVYVP-------PSIKDHDS-----ESLSVVNVREGTSVSLECESNAVPPPVITWYKNG 3098

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            ++I  S + ++   AD   L I +A   D G Y C A N AGR      L V  P   + 
Sbjct: 3099 RMITESTHVEI--LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3156

Query: 4721 LPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                 P R+++V     P       T    PTI WL+    I  +   ++      + L 
Sbjct: 3157 -----PEREVIVETISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQ 3211

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVE 4803
            I  +   D+G +TC A+   G+ +
Sbjct: 3212 IARSQHSDSGNYTCIASNMEGKAQ 3235



 Score =  116 bits (280), Expect = 2e-24
 Identities = 101/371 (27%), Positives = 155/371 (41%), Gaps = 39/371 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + W R +  ++ +   +I T +  S L ++ V   D+  +  +  + GG++  S  L V+
Sbjct: 551  LTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E          PP  T+  +N + T G  V +    TG     + W  N   +    R +
Sbjct: 610  E----------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYR 659

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             +  DGT  L I  A P+D+G Y C+A NSAG                DK     +   A
Sbjct: 660  -MTSDGT--LFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEA 701

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P +++    + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+
Sbjct: 702  P-KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLK 758

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I E    D GDY CVA N AGR T    L V  P      PA     D+ +  G      
Sbjct: 759  IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLP 813

Query: 4742 TQITSKIKPTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              +    +PTI+W R +   I   P     I +     L I N +  D GT+ C A    
Sbjct: 814  CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873

Query: 4800 GQVETSAKLVV 4810
            G++++   + V
Sbjct: 874  GKIQSETTVTV 884



 Score =  116 bits (279), Expect = 2e-24
 Identities = 101/380 (26%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 1148

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 1149 LCVATNIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 1257 HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 1305

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   +   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 1306 EL--TGREPGISILEEGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               ++   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 1364 KEQVS---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKL 1418

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 1419 FRATPEDAGRYSCKAINIAG 1438



 Score =  116 bits (278), Expect = 3e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 4181 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 4238

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 4239 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 4288

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 4289 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFV 4344

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 4345 YVKEP-------PVFKG-DYPSNWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 4389

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 4390 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 4442

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 4443 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 4498

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 4499 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4528



 Score =  112 bits (270), Expect = 3e-23
 Identities = 102/405 (25%), Positives = 159/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 1227

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 1282

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + E+GT  L+I    P D+G+Y CVA+
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEEGTL-LVIASVTPYDNGEYICVAV 1341

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDK---------------EQVSNVSVLLNQLTNLFCEVEG 1386

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 1387 TPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P     +++ V   +    + Q+     P I W ++G  L    P
Sbjct: 1445 NIDVLVPPTIIGTNFP-----KEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 1500 NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  109 bits (261), Expect = 3e-22
 Identities = 91/377 (24%), Positives = 164/377 (43%), Gaps = 37/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P++ W ++  P+K + +F+I     K  ++  Q    D   +  VA +  G  +  
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNFRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEIK 1724

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              + V          +VPP+     +     V    L+ LD  VTG+ P  + WLK+G+ 
Sbjct: 1725 YEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQL 1774

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P       
Sbjct: 1775 IDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP------- 1825

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K++         L +++V + + +   C   G P P++ W K D+ +  ++   +  
Sbjct: 1826 PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ-GNLKI 1876

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L + V+ 
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LNETVLV 1934

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
               P Q + +      P I W ++  L+  +     ++ G   ++ I +    D G + C
Sbjct: 1935 -SNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQ--IIDIESAQISDAGIYKC 1991

Query: 4794 RATTAAGQVETSAKLVV 4810
             A  +AG  E    L V
Sbjct: 1992 VAINSAGATELFYSLQV 2008



 Score =  108 bits (260), Expect = 4e-22
 Identities = 105/407 (25%), Positives = 165/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 3987 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 4044

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 4045 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 4094

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 4095 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMA 4151

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 4152 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 4195

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 4196 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 4250

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 4251 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 4302

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+ +  + VK
Sbjct: 4303 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVK 4347



 Score =  108 bits (259), Expect = 6e-22
 Identities = 104/396 (26%), Positives = 162/396 (40%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2965 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLI-VPGGRTLQI 3023

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N  G +K   +L V           VPPS     + +   VNV
Sbjct: 3024 IR-AKVSDGGEYTCIAINXAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 3072

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 3073 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 3130

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 3131 CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 3175

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 3176 ATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3235

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 3236 KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3292

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 3293 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3328



 Score =  107 bits (258), Expect = 7e-22
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 3055 VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI--LAD 3112

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 3113 GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 3162

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 3163 VETISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3222

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 3223 YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 3268

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 3269 CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3328

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L   + Y       + + T    P I WL+ G  +P
Sbjct: 3329 EDRIFNLNVYVTPTIRGNKDEAEKL---MTYVDTSINIECRXTGTPPPQINWLKNGLPLP 3385

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 3386 LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 3421



 Score =  107 bits (256), Expect = 1e-21
 Identities = 110/409 (26%), Positives = 168/409 (41%), Gaps = 41/409 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 850

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 851  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 902

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 903  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 959

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 960  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 1003

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSS-AKFSAGADG-SLYVVSPEGEESGEYVCTATNTAGYAK 1061

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +L  L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 1062 RKVQLTVYVRPRVFGDLRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V
Sbjct: 1122 PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score =  106 bits (255), Expect = 2e-21
 Identities = 99/368 (26%), Positives = 150/368 (40%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 3272 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 3331

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         T    ++N+        + + TGT P  + WLKNG  
Sbjct: 3332 IFNLNVYVTPTIRGNKDEAEKLMTYVDTSINI--------ECRXTGTPPPQINWLKNGLP 3383

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 3384 LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 3439

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 3440 ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 3487

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 3488 HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 3542

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 3543 VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 3599

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 3600 CLASSPAG 3607



 Score =  105 bits (253), Expect = 3e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 3364 ECRXTGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 3421

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 3422 VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3471

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 3472 RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 3527

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 3528 -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 3574

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 3575 -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 3630

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 3631 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 3688

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 3689 ANYTCVASNIAGKTTREFILTV 3710



 Score =  105 bits (251), Expect = 5e-21
 Identities = 103/378 (27%), Positives = 149/378 (39%), Gaps = 31/378 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 1006 GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPEG-EESGEYVCTATNTAGYAKRK 1063

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              L V  + R   G +   S     + ++V +G+ V L  +V    P  + W K  + + 
Sbjct: 1064 VQLTVYVRPRVF-GDLRGLSQDKPVE-ISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 1121

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P          G+  + I E    DSG Y CVA N AG      +  V            
Sbjct: 1122 PFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNV------------ 1167

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675
                + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S   
Sbjct: 1168 ----HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNP- 1222

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIVVY 4733
             + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V  
Sbjct: 1223 -DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA- 1280

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
              Q  +F        KPTI+WL  G  L    P   ++ EG   +L+I +    D G + 
Sbjct: 1281 -NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEEG--TLLVIASVTPYDNGEYI 1337

Query: 4793 CRATTAAGQVETSAKLVV 4810
            C A   AG  E    L V
Sbjct: 1338 CVAVNEAGTTERKYNLKV 1355



 Score =  104 bits (250), Expect = 7e-21
 Identities = 96/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKKE 1817

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 1818 FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 1867

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 1868 NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 1919

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK + L+  S    M+  
Sbjct: 1920 SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGST--SMTFL 1970

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1971 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 2025

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +T   DTG +TC 
Sbjct: 2026 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSTQISDTGRYTCV 2084

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 2085 AVNAAGEKQRDIDLRV 2100



 Score =  104 bits (249), Expect = 9e-21
 Identities = 96/377 (25%), Positives = 156/377 (41%), Gaps = 34/377 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P  +W + +  +  +P   + +  +   L I +V ++D   +  VA N  GT   +
Sbjct: 916  GNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKT 972

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             ++VV           V P+     Q ++   G  V L  K +G     V W K G+ + 
Sbjct: 973  TSVVVH----------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                      DG+  L ++    ++SG+Y C A N+AG A+   +  V +     +P+  
Sbjct: 1023 TSSAKFSAGADGS--LYVVSPEGEESGEYVCTATNTAGYAKRKVQLTVYV-----RPRVF 1075

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT- 4674
                    +  +P++  ++A G+ +   C++   P P + W K  +LI P   F    T 
Sbjct: 1076 GDLRGLSQD--KPVEISVLA-GEEVTLPCEVKSLPPPIITWAKETQLISP---FSPRHTF 1129

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +++I+E    D G Y CVA N AG VT A KL V  P +    P     + + V  
Sbjct: 1130 LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQV 1184

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            GQ             P I W + G+ +    D +      +  L I      D G +TC 
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCV 1242

Query: 4795 ATTAAGQVETSAKLVVK 4811
            AT  AG  ET   L V+
Sbjct: 1243 ATNIAGTDETEITLHVQ 1259



 Score =  103 bits (248), Expect = 1e-20
 Identities = 101/395 (25%), Positives = 158/395 (40%), Gaps = 34/395 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP    + Q   V   +      + D  P P + W ++  P+   P   I     +S+L 
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSIS--ENRSVLK 2160

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTS 4527
            I    V+D+  +   A N  G           EK+       VPP+   + +   + V  
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKT---------EKKNYNVNIWVPPNIGGSDELTQLTVIE 2211

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G L+ L  + +G  P ++ W K G  V  D   ++    G   L I  A   D+  Y CV
Sbjct: 2212 GNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCV 2271

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG A+ +    V +  T       T + + P EI       IV  G++I   C++ 
Sbjct: 2272 ASNVAGTAKKEYNLQVYIRPT------ITNSGSHPTEI-------IVTRGKSISLECEVQ 2318

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PTV W K G  LIK +K  ++    + + L++      D G Y CVA N AG    
Sbjct: 2319 GIPPPTVTWMKDGHPLIK-AKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2375

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V  P     +       +I V E        + +    P+  W ++G  +  +  
Sbjct: 2376 KYDLSVHAPPSI--IGNHRSPENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNS 2433

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +++  G   +L +  T  ED G +TC    AAG+
Sbjct: 2434 VRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2466



 Score =  103 bits (246), Expect = 2e-20
 Identities = 99/391 (25%), Positives = 154/391 (39%), Gaps = 34/391 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V  +   R E E  G P P + W ++  P+ +  +  +   S   IL +    + D+  +
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSTQISDTGRY 2081

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G  +   +L V           VPP+     QNV+V   Q V L  +     
Sbjct: 2082 TCVAVNAAGEKQRDIDLRV----------YVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  + WLK+G  +       I E      L I +A  QD+G+Y C A N AG        
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNVAG-------- 2181

Query: 4602 VVSLPATKDKPKPQTKAANAPPEI--IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
                   K + K        PP I   + L    V EG  I   C+  G P P + W K 
Sbjct: 2182 -------KTEKKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKK 2234

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
               +      ++   +    L+IS A   D   Y CVA N AG       L+V       
Sbjct: 2235 GSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTIT 2294

Query: 4720 NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
            N  +     +I+V  G+    + ++     PT+ W+++G  + +    +++ EG+  +L 
Sbjct: 2295 NSGSHPT--EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQ 2350

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + N +  DTG + C A   AG  +    L V
Sbjct: 2351 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2381



 Score =  101 bits (242), Expect = 6e-20
 Identities = 101/369 (27%), Positives = 145/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W +    I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 3178 GIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3237

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 3238 YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 3287

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 3288 IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 3340

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +    D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 3341 PTIRGNKDEAEKLMTYVDT------SINIECRXTGTPPPQINWLKNGLPLPLSSHIRL-- 3392

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 3393 LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 3449

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 3450 KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 3507

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 3508 IASNEAGEV 3516



 Score =  101 bits (241), Expect = 8e-20
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 3804 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3863

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 3864 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 3913

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 3914 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 3971

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 3972 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 4014

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 4015 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 4072

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 4073 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4126

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 4127 RVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4166



 Score =  100 bits (240), Expect = 1e-19
 Identities = 88/301 (29%), Positives = 128/301 (42%), Gaps = 37/301 (12%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG       + SGNP+P V W K G+ +  S+     +     +L V + +  +SG Y  
Sbjct: 994  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPEGEESGEYVC 1051

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 1052 TATN------TAGYAKRKVQLTVYV---RPRVFGDLRGLSQDKPVEIS------------ 1090

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 1091 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 1143

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 579  Y 579
            +
Sbjct: 1257 H 1257



 Score =  100 bits (240), Expect = 1e-19
 Identities = 118/484 (24%), Positives = 190/484 (39%), Gaps = 57/484 (11%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            ++ G P P +SW +   P+    K +       G  +L I +    D GEYTC A N  G
Sbjct: 2988 EVSGFPPPDLSWLKNXQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINXAG 3043

Query: 154  EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
            E+      +VY+ P                   S ++E ++                  Y
Sbjct: 3044 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITW--------Y 3095

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
             NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 3096 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 3153

Query: 268  IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
            I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 3154 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIA 3213

Query: 327  NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 3214 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 3254

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                         D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 3255 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3302

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            +  L I     SD+G  TCVA N +GE      LNV     +   K  +    L      
Sbjct: 3303 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNK--DEAEKLMTYVDT 3359

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
             + +  R  GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A 
Sbjct: 3360 SINIECRXTGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVAS 3417

Query: 567  NVAG 570
            N AG
Sbjct: 3418 NRAG 3421



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 1242 VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 1293

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 1294 PKPTIKWLHNGRELTGREP-GISILEEGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 1353 LKVH----------VPPVIKDKEQVSNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 1400

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 1453

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 1454 IIGTNFPKEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 1506

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 1507 GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 1561

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 1562 NSLIKLECKTRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 1619

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 1620 VANVAGTAEKS 1630



 Score =  100 bits (239), Expect = 1e-19
 Identities = 106/423 (25%), Positives = 169/423 (39%), Gaps = 31/423 (7%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKK-MQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T +   A  +ER + G      P I  +  ++  +V E +      E  G P+P I W++
Sbjct: 2457 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK 2516

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRR 4505
            +  P++   D   H  S    L I  V V  +  +  +A +  G    S +L V      
Sbjct: 2517 DGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2574

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
             G G    P      ++V V       L  +     P  + W K+G  ++ +   +IL  
Sbjct: 2575 AGVGSDGNP------EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL-- 2626

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             G  TL IL A   ++G+Y CVA N AGE     E  V +P   +K         +P E+
Sbjct: 2627 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL-SPKEV 2685

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
                K K+      +   C+    P  ++ WYK  + +K   +  ++  A+ +TL+I EA
Sbjct: 2686 ----KIKV---NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA--ANGHTLQIKEA 2736

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-------VVYEGQPA 4738
               D G Y CVA N AG   +   + +  P     L  +  + D         V    P 
Sbjct: 2737 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2796

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +  +   PT+ W ++G   P T   +++      VL I     ED G +TC A   
Sbjct: 2797 SLYCETNAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNE 2854

Query: 4799 AGQ 4801
            AG+
Sbjct: 2855 AGE 2857



 Score =   99 bits (238), Expect = 2e-19
 Identities = 89/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 1227

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 1268

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                   P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 1269 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 1318

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
             G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ S ++V  
Sbjct: 1319 EGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVSNVSVLL 1374

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 1375 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCK 1432

Query: 565  AQNVAGST 572
            A N+AG++
Sbjct: 1433 AINIAGTS 1440



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 4079 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF 4138

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 4139 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 4185

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 4186 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 4242

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 4243 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4286

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 4287 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKATG 4342

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 4343 FVYVKEPPVFKGDYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 4395

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 4396 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 4439



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 100/399 (25%), Positives = 163/399 (40%), Gaps = 41/399 (10%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVF 4474
            KM    V      + E +  G P+P+I WY++N  +  S      TF  +  +I I    
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSM---TFLNRGQIIDIESAQ 1982

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + D+ ++  VA N  G  +   +L V           V PS + +   V V     VRL+
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH----------VAPSISGSNNMVAVVVNNPVRLE 2032

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +  G     + WLK+G  V     N +    G   L +      D+G+Y CVA+N+AGE
Sbjct: 2033 CEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSTQISDTGRYTCVAVNAAGE 2091

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             + D +  V +                PP I+   ++  V   QA+E  C+    P PT+
Sbjct: 2092 KQRDIDLRVYV----------------PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135

Query: 4655 QWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA-AKLKV 4712
             W K G  L+K      +S + +   L+I +A  +D G Y C A N AG+       + +
Sbjct: 2136 TWLKDGHPLLKKP---GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKKNYNVNI 2192

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIH 4771
              P    N+     L  + V EG       + +    P + W ++G+ ++ ++     I 
Sbjct: 2193 WVP---PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL 2249

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             G    L I    + D   ++C A+  AG  +    L V
Sbjct: 2250 SGGRQ-LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2287



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 82/299 (27%), Positives = 122/299 (40%), Gaps = 40/299 (13%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P    +  G     + ++ G P P VTW K+G  LI +   EI+    H  L+++N   S
Sbjct: 2300 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEGH-ILQLKNIHVS 2357

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            D+G Y  +A N  G       L+V +P  S + + RS                       
Sbjct: 2358 DTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHRS----------------------- 2393

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ + V +   V+        C  +G P P  TWF +   +    + +IL   SG   L 
Sbjct: 2394 PENISVVEKNSVS------LTCEASGIPLPSTTWFKDGWPVSLSNSVRIL---SGGRMLR 2444

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            +   T+ D+G  TCV RN +GE      L+V+    +V    +E    + V+E + V L 
Sbjct: 2445 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE---DVKVKEKQSVTLT 2501

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG P+    +   H   G   L I   +      Y C A + AG
Sbjct: 2502 CEVTGNPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2558



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 95/380 (25%), Positives = 156/380 (41%), Gaps = 34/380 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E +  P P + WY++  P+ +S    I       +L I +  VED+  +  VA N  G  
Sbjct: 2801 ETNAAPPPTLTWYKDGHPLTSSDKVLI--LPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2858

Query: 4493 KCSANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                ++ V+     +G    +P       + V V   +   ++   +G+      W K+G
Sbjct: 2859 SLQYDVRVLVPPIIEGANSDLP-------EEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2911

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            + +  D  +K L       L IL     D G+Y CVA N+AG A+               
Sbjct: 2912 QPLLEDDHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAK--------------- 2954

Query: 4612 PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             K      + PP +I P  + + V     I  +C++ G P P + W K  + IK +    
Sbjct: 2955 -KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTL 3013

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +       TL+I  A   D G+Y C+A N AG       L V  P    +  + + L  +
Sbjct: 3014 I--VPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSES-LSVV 3070

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG     + +  +   P I W + G +I E+   +++ +G   +L I      DTG 
Sbjct: 3071 NVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQ 3128

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + CRA   AG+ + +  L V
Sbjct: 3129 YVCRAINVAGRDDKNFHLNV 3148



 Score = 98.3 bits (234), Expect = 6e-19
 Identities = 86/375 (22%), Positives = 154/375 (41%), Gaps = 35/375 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E E  G P P + W ++  P+  +   +I       IL ++ + V D+  +  VA N  G
Sbjct: 2314 ECEVQGIPPPTVTWMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2371

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT---LTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
                  +L V            PPS      + +N++V     V L  + +G       W
Sbjct: 2372 MTDKKYDLSVH----------APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSTTW 2421

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G  V   + N +    G   L +++   +D+G+Y CV  N+AGE R      V +P 
Sbjct: 2422 FKDGWPVS--LSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP- 2478

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                  P     N        L+D  V E Q++  +C++ G P+P + W+K  + ++  +
Sbjct: 2479 ------PHIVGENT-------LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2525

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               +   +    L+I+       G Y C+A + AG  + +  L V        + +    
Sbjct: 2526 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2583

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
             D+ V    P     +  S    TI W ++G  +    + +++  G    +L  N  E++
Sbjct: 2584 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQIL--NAQEDN 2641

Query: 4788 TGTFTCRATTAAGQV 4802
             G ++C AT  AG++
Sbjct: 2642 AGRYSCVATNEAGEM 2656



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 95/388 (24%), Positives = 159/388 (40%), Gaps = 36/388 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E        E  G PLP   W+++ +P+  S   +I   S   +L + Q  +ED+  +
Sbjct: 2399 VVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRI--LSGGRMLRLMQTTMEDAGQY 2456

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTG 4539
              V  N  G          EE++  G   +VPP      T ++V V   Q V L  +VTG
Sbjct: 2457 TCVVRNAAG----------EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2506

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                ++ W K+G+ +Q D  + I+   G   L I       +G+Y C+A + AG      
Sbjct: 2507 NPVPEITWHKDGQPLQEDEAHHII--SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2564

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
               V +      P      ++  PE      D  V         C+    P  T+ W+K 
Sbjct: 2565 SLNVFV-----SPTIAGVGSDGNPE------DVTVILNSPTSLVCEAYSYPPATITWFKD 2613

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP---D 4716
               ++ ++  ++       TL+I  A  ++ G Y CVA N AG +    ++KV  P   +
Sbjct: 2614 GTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIIN 2671

Query: 4717 QADNL-PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
            + D   P L+P +++ +        + +  +    ++ W ++G   P   D  +    N 
Sbjct: 2672 KGDLWGPGLSP-KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ--PLKSDDHVNIAANG 2728

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              L I      DTG +TC A+  AG+ E
Sbjct: 2729 HTLQIKEAQISDTGRYTCVASNIAGEDE 2756



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 64/209 (30%), Positives = 88/209 (42%), Gaps = 8/209 (3%)

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFV---KVCQDRDVTEGKMTRFDCRVTGRPYP 421
            +   QY    +    EER       L P  +      +D  V E +     C VTG P P
Sbjct: 2451 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2510

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            E+TW  + + +++D  H I+   SG   L ITNV +  +G  TC+A + +G  +    LN
Sbjct: 2511 EITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2567

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V     +           + V    P  L   A   P   ITW KDG P+  N  +RI  
Sbjct: 2568 VFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP 2627

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G  TL I  A+  +A  Y C A N AG
Sbjct: 2628 --GGRTLQILNAQEDNAGRYSCVATNEAG 2654



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 3841 NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 3897

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 3898 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 3952

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 3953 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 4007

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 4008 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4065

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 4066 GTALGKIKL 4074



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 87/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ K  G     + W 
Sbjct: 1533 KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPAITWY 1582

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 1583 KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 1638

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   C   G P P + W K    +K +  
Sbjct: 1639 -----PMIEG-----NLATPLNKQVVI-AHSLTLECNAAGNPSPILTWLKDGVPVKANDN 1687

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
            F++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 1688 FRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 1742

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G LI E   F+++  G    L+I      +T
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNT 1800

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTV 1822



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 96/379 (25%), Positives = 156/379 (41%), Gaps = 42/379 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W   +  I  S  +++ +  T   L I+    +D+ ++  +A N  GT K +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            + L   E           P   +    + V  G +  ++ K +G  P  V W K   +++
Sbjct: 694  STLRYIEA----------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELR 743

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P   +  L  D    LL I E    D+G Y CVAIN AG A                   
Sbjct: 744  P---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI--------------- 785

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
             T    +PP  I+   D  +  G  +   C + G P PT++W + D +   S+ F +S  
Sbjct: 786  -TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 4675 ADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +   T  L I   +  D+G Y C A N  G+  + ++  VT       L  ++P    V+
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK--IQSETTVTVTGLVAPLIGISPSVANVI 902

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQ      T +     P  +W++  A++ + P   +  +G+   L I     +D G +
Sbjct: 903  -EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEY 958

Query: 4792 TCRATTAAGQVETSAKLVV 4810
            TC A+  AG    +  +VV
Sbjct: 959  TCVASNVAGTNNKTTSVVV 977



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 87/367 (23%), Positives = 147/367 (40%), Gaps = 17/367 (4%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W+++  P++++ + +I        L I     +++  ++ VA N  G       
Sbjct: 2604 PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2661

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V       +G +  P   L+ + V +     + L+ +        + W K+G+ ++ D
Sbjct: 2662 VKVYIPPIINKGDLWGPG--LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSD 2719

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                I      +TL I EA   D+G+Y CVA N AGE   D +  + +P +  K      
Sbjct: 2720 DHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2777

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTAD 4676
              +         KD I+     I   C+    P PT+ WYK G  L    K   +     
Sbjct: 2778 MLDTGRN--GEAKDVII--NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PG 2830

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L+I  A  ED G Y CVA N AG  ++   ++V  P   +   +  P  ++ V   +
Sbjct: 2831 GRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIEGANSDLP-EEVTVLVNK 2889

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  +   +    P   W ++G  + E    + +   N  +L I NT   D G + C A 
Sbjct: 2890 SALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNGRILQILNTQITDIGRYVCVAE 2947

Query: 4797 TAAGQVE 4803
              AG  +
Sbjct: 2948 NTAGSAK 2954



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 98/397 (24%), Positives = 157/397 (39%), Gaps = 41/397 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N  V  
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1934

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+   +        L       + I  A   D+G Y+CV
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1992

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1993 AINSAGA----TELFYSL------------QVHVAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++     D G Y CVA N+AG    
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSTQISDTGRYTCVAVNAAGEKQR 2094

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 2095 DIDLRVYVPPN-----IMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 2149

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
              +    N +VL I +   +DTG +TC AT  AG+ E
Sbjct: 2150 LSI--SENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 56/158 (35%), Positives = 77/158 (48%), Gaps = 6/158 (3%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V+G P P+++W  N + I+ + N  I+    G   L I    +SD G  TC+A N +G
Sbjct: 2987 CEVSGFPPPDLSWLKNXQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINXAG 3043

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 3044 ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT 3102

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 3103 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 3138



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 3555 GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 3608

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 3609 -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 3662

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 3663 LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 3713

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 3714 PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 3763

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 3764 LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 3816

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 3817 IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 3876

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 3877 CTVTNGAGDDKRTVDLTVQ 3895



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 3554 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 3603

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 3604 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 3641

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
              +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 3642 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 3697

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 3698 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3752

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 3753 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3799



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 1835 ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 1892

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 1893 AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1947

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1948 PVPVITWYKDNCLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 2000



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 4010 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 4065

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 4066 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 4120

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 4121 VESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4164



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 13/217 (5%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
            R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  + + I +    KIL+N      L+I    +S++G+  C+A N +G+   +  + V 
Sbjct: 1767 MWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTD 542
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I + 
Sbjct: 1824 VPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSS 1879

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 1880 G--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 49/290 (16%)

Query: 293  PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGY 352
            P   +TWFK+G  L ++    I+      TL++ N Q+ ++G Y+ +A N  G ++    
Sbjct: 2604 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2661

Query: 353  LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFD 412
            + V  P                       + ++    L+P+ VK+  +  +T       +
Sbjct: 2662 VKVYIPP-------------------IINKGDLWGPGLSPKEVKIKVNNTLT------LE 2696

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C     P   ++W+ + + ++ D +  I  N    H L I    +SD+G  TCVA N +G
Sbjct: 2697 CEAYAIPSASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAG 2753

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNV----REGE--------PVVLNARAVGTPTP 520
            E      +N+      V P F + +   N+    R GE        P+ L       P P
Sbjct: 2754 EDELDFDVNI-----QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2808

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +TW KDG P+  + ++ I    G   L IPRAK  DA  Y C A N AG
Sbjct: 2809 TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAG 2856



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 87/350 (24%), Positives = 145/350 (41%), Gaps = 52/350 (14%)

Query: 229 RLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPV-----SPPKIAQKPRNSKLQEGAD 282
           R L  +S   +S+     GE    +S+E   S   V      PPK+   P+N     G++
Sbjct: 569 RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSE 628

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
                  +G P+P++ W  N   ++ S+++ + +     TL ++N    D+G Y      
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY------ 679

Query: 343 PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
             GC+ ++      + T+              +Q  T   IE      AP+ + V  +  
Sbjct: 680 --GCLASNS-----AGTD--------------KQNSTLRYIE------APKLMVVQSELL 712

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L I      D+G 
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGD 769

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TCVA N++G    +  L+V        P F++  + +++  G  V L     G P P I
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI 824

Query: 523 TWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            W++ D +PI   P  +   +      L I    ASD   Y C A+N  G
Sbjct: 825 KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFG 874



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 73/302 (24%), Positives = 132/302 (43%), Gaps = 33/302 (10%)

Query: 272  PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
            P+  K++       + +    P   ++W+K+GQ L  S+ H  I  + HT L+++  Q S
Sbjct: 2682 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANGHT-LQIKEAQIS 2739

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR--ETEERIEISEKA 389
            D+G YT        C+ ++  +A E   +  V  Q    +  + Q+  E    ++     
Sbjct: 2740 DTGRYT--------CVASN--IAGEDELDFDVNIQ----VPPSFQKLWEIGNMLDTGRNG 2785

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
             A         +DV         C     P P +TW+ +   +    + K+L+   G   
Sbjct: 2786 EA---------KDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS--SDKVLILPGGR-V 2833

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I    + D+G  TCVA N++GE + Q  + V+    ++     +    + V   +  +
Sbjct: 2834 LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL-VPPIIEGANSDLPEEVTVLVNKSAL 2892

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +   + G+P PR +WQKDG P++ +   +  ++G    L I   + +D   Y C A+N A
Sbjct: 2893 IECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNG--RILQILNTQITDIGRYVCVAENTA 2950

Query: 570  GS 571
            GS
Sbjct: 2951 GS 2952



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 75/311 (24%), Positives = 130/311 (41%), Gaps = 40/311 (12%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 3245 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 3304

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 3305 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 3349

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               +EK +   +V    D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 3350 ---AEKLMT--YV----DTSIN------IECRXTGTPPPQINWLKNGLPLPLSSHIRLL- 3393

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
              +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 3394 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 3449

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 3450 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 3506

Query: 563  CTAQNVAGSTA 573
            C A N AG  +
Sbjct: 3507 CIASNEAGEVS 3517



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 3626 TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 3683

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 3684 DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 3733

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 3734 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 3791

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 3792 TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3835

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 3836 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3895

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 3896 VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3950

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 3951 GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 3985



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 3713 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 3770

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 3771 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 3820

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 3821 QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3880

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 3881 NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 3924

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 3925 PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 3981

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 3982 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 4036

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 4037 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4077



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 9/163 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 2030 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSTQISDTGRYTCVAVN 2087

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 2088 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 2142

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P++  P L I  +   S L I  A+  D   Y C A NVAG T
Sbjct: 2143 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKT 2183



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 722  ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 779

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 780  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 829

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 830  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 885

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 886  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 936  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 986

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 987  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPEGE 1044

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 55/181 (30%), Positives = 84/181 (46%), Gaps = 15/181 (8%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
            P+ V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 1460 PKEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 1510

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 1567

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              +  G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 1568 ECKTRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 1625

Query: 571  S 571
            +
Sbjct: 1626 T 1626



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 3448 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 3504

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 3505 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 3561

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 3562 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3607



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 59/204 (28%), Positives = 86/204 (42%), Gaps = 14/204 (6%)

Query: 380  EERIEISEKALAPQFVK-----VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            E+ ++   + L P  ++     + ++  V   K    +C  +G P P  +W  + + + +
Sbjct: 2857 EDSLQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2916

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
            D +HK L N      L I N  ++D G   CVA N +G       LNV     V+ PK  
Sbjct: 2917 DDHHKFLSN---GRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-- 2971

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
                 L V     + L     G P P ++W K+  PI  N    I    G  TL I RAK
Sbjct: 2972 --SENLTVVVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVP--GGRTLQIIRAK 3027

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD   Y C A N AG +  +  L
Sbjct: 3028 VSDGGEYTCIAINXAGESKKKFSL 3051



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 102/476 (21%), Positives = 179/476 (37%), Gaps = 50/476 (10%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W +   P V   + +++  + +G V  + K +   D G YTC A N  GE  
Sbjct: 1852 GIPNPSITWLKDDQP-VNTAQGNLKI-QSSGRVLQIAKTLLE-DAGRYTCVATNAAGETQ 1908

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              + +                    VS  V+ +           +        +  T  +
Sbjct: 1909 QHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMT 1968

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
              +  ++   E   + +    + +     G      +TE+  SL     P I+       
Sbjct: 1969 FLNRGQIIDIESAQISDAGIYKCVAINSAG------ATELFYSLQVHVAPSISGSNNMVA 2022

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +      + + +  G P P +TW K+G   ++S  + +        L + +TQ SD+G Y
Sbjct: 2023 VVVNNPVRLECEARGIPAPSLTWLKDGSP-VSSFSNGLQVLSGGRILALTSTQISDTGRY 2081

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T        C+      AV +  E              +QR+ + R+ +    +  +   
Sbjct: 2082 T--------CV------AVNAAGE--------------KQRDIDLRVYVPPNIMGEE--- 2110

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              Q+  V   +     C+    P P +TW  +   +       I  N S    L I +  
Sbjct: 2111 --QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---VLKIEDAQ 2165

Query: 457  LSDSGVVTCVARNKSGETAFQ-CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
            + D+G  TC A N +G+T  +   +N+     +      +  + L V EG  + L   + 
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKKNYNVNIWVPPNIGGS---DELTQLTVIEGNLISLLCESS 2222

Query: 516  GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            G P P + W+K G P++ +   R+    G   L I  A+ SDAA Y C A NVAG+
Sbjct: 2223 GIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2278



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 82/299 (27%), Positives = 127/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 4261 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 4316

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K +  + V+E          PP F     +  +    G
Sbjct: 4317 ERVSKEDSGTYVCTAENSVGFVKATGFVYVKE----------PPVFKGDYPSNWIEPLGG 4366

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 4367 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 4422

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 4423 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 4465

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 4466 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 4521



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 107/493 (21%), Positives = 179/493 (36%), Gaps = 58/493 (11%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 3262 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 3319

Query: 146  CTARNQYGEAI----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQS 201
            C A N  GE       +VY+ P               Y   S  +E +  GT        
Sbjct: 3320 CVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMTYVDTSINIECRXTGTPPPQINWL 3378

Query: 202  RQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLG 261
            +    +  ++     +    +V       + +V+    +     G  +   + ++     
Sbjct: 3379 KNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----- 3431

Query: 262  PVSPPKIAQKPRNSKLQ--EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
              +PP +       ++   +G+         G P P + W ++GQ L   + H  ++TH 
Sbjct: 3432 -FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG 3489

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRET 379
               L++   +  DSG YT +A N  G +     L V  P           +I  +++ E 
Sbjct: 3490 -MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP----------PHINGSEEHE- 3537

Query: 380  EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
                EIS     P     C    +   KMT       GRP P+        Q++      
Sbjct: 3538 ----EISVIVNNP-LELTCIASGIPAPKMTWMK---DGRPLPQTD------QVQ------ 3577

Query: 440  ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
                  G   L I+   + D+G  TC+A + +G+   +  + V     +         + 
Sbjct: 3578 ---TLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITV 3634

Query: 500  LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
            L  R+   V L  ++   P P ITW ++G  +   P +RI +  G   L I  A   D A
Sbjct: 3635 LRNRQ---VTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTA 3689

Query: 560  WYQCTAQNVAGST 572
             Y C A N+AG T
Sbjct: 3690 NYTCVASNIAGKT 3702



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 55/177 (31%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 4181 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 4237

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 4238 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4292

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G       +Y
Sbjct: 4293 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVY 4345



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/177 (30%), Positives = 79/177 (44%), Gaps = 13/177 (7%)

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            V  D  V    + + +C+  G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 1553 VTTDISVLINSLIKLECKTRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 1609

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
            +SDS   TC   N +G       ++V      V P      +T LN  V     + L   
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECN 1664

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P+P +TW KDGVP+  N   RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNFRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 1719



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK- 396
            L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 1307 LTGREPGISILEEGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 1363

Query: 397  --VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
                 +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 1364 KEQVSNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GKILKLFR 1420

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
             T  D+G  +C A N +G +     ++V+    ++   F +  S +  R+   V L  + 
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPKEVSVVLNRD---VALECQV 1477

Query: 515  VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 1533

Query: 572  TATRARL 578
             A   +L
Sbjct: 1534 QAKDIKL 1540



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 52/187 (27%), Positives = 81/187 (43%), Gaps = 11/187 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+   + +++  T G      C  TG P P++ W +ND  I   + +++    + +  L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM----TSDGTLF 667

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V+ 
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVME 722

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N AG 
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGR 780

Query: 572 TATRARL 578
              +  L
Sbjct: 781 ATGKITL 787



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 909

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 966

Query: 570 GS 571
           G+
Sbjct: 967 GT 968



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 69/281 (24%), Positives = 110/281 (39%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 1851 NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 1901

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 1902 NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1938

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+  D  +         +N      + I +  +SD+G+  CVA N
Sbjct: 1939 QLECKAAGNPVPVITWY-KDNCLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAIN 1995

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1996 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +   + SD   Y C A N AG
Sbjct: 2051 P-VSSFSNGLQVLSGGRILALTSTQISDTGRYTCVAVNAAG 2090



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 4371 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4426

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 4427 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 4481

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 4482 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 4522



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG +    C  +G P P + W      +  D   ++ +  SG   L I+    SD+ +
Sbjct: 2209 VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRIL-SGGRQLQISIAEKSDAAL 2267

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             +CVA N +G    +  L V  +  +         + + V  G+ + L     G P P +
Sbjct: 2268 YSCVASNVAGTAKKEYNLQVYIRPTITNSG--SHPTEIIVTRGKSISLECEVQGIPPPTV 2325

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            TW KDG P+I    + I  +G    L +     SD   Y C A NVAG T
Sbjct: 2326 TWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAVNVAGMT 2373



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 53/180 (29%), Positives = 78/180 (43%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 4261 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 4315

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G       + V E      P F   + +  +   G   +L
Sbjct: 4316 IERVSKEDSGTYVCTAENSVGFVKATGFVYVKE-----PPVFKGDYPSNWIEPLGGNAIL 4370

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 4371 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4427



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 77/345 (22%), Positives = 130/345 (37%), Gaps = 37/345 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I +V + D   +  +A +  GT +      V E          PP       NV VT 
Sbjct: 484  LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE----------PPPVIQVPNNVTVTP 533

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L   +      ++ W +N + V+     +I       +L +      D+G+Y C+
Sbjct: 534  GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCM 592

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
              +  G +       V                  PP++    K++    G  +   C   
Sbjct: 593  VSSEGGSSAASVFLTVQ----------------EPPKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P P + W   D  I  S  ++M  T+D  TL I  A P+D G Y C+A NSAG     
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRM--TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            + L+  +  +      +    +++V  G     + + +    P ++W +    +   P  
Sbjct: 694  STLRYIEAPK-----LMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPST 746

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +I +    +L I  T + D G +TC A   AG+      L V S
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 12/177 (6%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +D  V     T   C     P   +TWF +   +  + N +IL    G   L I N    
Sbjct: 2584 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQED 2640

Query: 459  DSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            ++G  +CVA N++GE      + V     I K  +  P    +   + ++    + L   
Sbjct: 2641 NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE 2698

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A   P+  ++W KDG P+  +  + I  +G   TL I  A+ SD   Y C A N+AG
Sbjct: 2699 AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAG 2753



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 3763 ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3819

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 3820 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 3877

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 3878 TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3932

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 3933 KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3984



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L I  V   D+G  TC+
Sbjct: 4095 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQIAFVQPGDAGHYTCM 4150

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 4151 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4205

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 4206 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4247



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 61/277 (22%), Positives = 113/277 (40%), Gaps = 28/277 (10%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            ++   V    P  + +++NG  +  D   + L+E  + +L I +    D G YEC+A++S
Sbjct: 448  QIPCSVDSLLPFTLSFVRNGVTLGVD---QYLKESASVSLDIAKVTLSDEGFYECIAVSS 504

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG  R      VS                 PP +I+   +  V  G+    +C I+    
Sbjct: 505  AGTGRAQTFFDVS----------------EPPPVIQVPNNVTVTPGERAVLTCLIISAVD 548

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
              + W + D+ ++ ++  ++ RT    +L +      D G+Y C+  +  G    +  L 
Sbjct: 549  YNLTWQRNDRDVRLAEPARI-RTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            V +P +   +P     ++     G         T   KP I W      I  +  ++M  
Sbjct: 608  VQEPPKVTVMP-----KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            +G    L I N   +D G + C A+ +AG  + ++ L
Sbjct: 663  DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 54/178 (30%), Positives = 75/178 (42%), Gaps = 12/178 (6%)

Query: 402  DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
            +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 955

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 956  GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 1010

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             + W K G  +I     +  + G   +L +   +  ++  Y CTA N AG    + +L
Sbjct: 1011 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPEGEESGEYVCTATNTAGYAKRKVQL 1066



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 12/188 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++V  +  VT G+     C +       +TW  NDR +R        +    N +L 
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVL 510
           + +V  +D+G   C+  ++ G +A    L V E  +V V PK        +   G  V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK------NQSFTGGSEVSI 631

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P+I W  + + I+ +   R+ +DG   TL I  A   DA  Y C A N AG
Sbjct: 632 MCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688

Query: 571 STATRARL 578
           +    + L
Sbjct: 689 TDKQNSTL 696



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N  G+++    L   
Sbjct: 2997 LSWLKNXQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVY 3054

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   EC    V  P   I WY NG+ +  ST ++ 
Sbjct: 3055 VPPSIKDHDSESLSVVNV---REGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEI 3109

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 3110 LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 3149



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 104/477 (21%), Positives = 174/477 (36%), Gaps = 55/477 (11%)

Query: 99   PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            P P ++W +   PL   +K  +      G   L I +    D G YTC A N+ GE    
Sbjct: 2806 PPPTLTWYKDGHPLTSSDKVLIL----PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQ 2861

Query: 159  ----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                V + P                 + S  +E  + G+        +  Q +   +   
Sbjct: 2862 YDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD--H 2919

Query: 215  HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
            H    + ++       + ++     + +   G +    +  +      V P  I  K  N
Sbjct: 2920 HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-----VPPSVIGPKSEN 2974

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
              +          ++SG P P ++W KN Q  I  N + +I      TL++   + SD G
Sbjct: 2975 LTVVVNNFISLTCEVSGFPPPDLSWLKNXQP-IKLNTNTLIVPGGR-TLQIIRAKVSDGG 3032

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERIEISEKALAPQ 393
             YT +A N  G       L V  P    ++D  S+ ++    RE T   +E    A+ P 
Sbjct: 3033 EYTCIAINXAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSLECESNAVPPP 3090

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
             +   ++     G+M      +T   + E+   + D Q+   +  K  V+++G +     
Sbjct: 3091 VITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVSDTGQYVCRAI 3134

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV               +G       LNV     +  P+      T++     PV L   
Sbjct: 3135 NV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS----NPVTLTCD 3175

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C A N+ G
Sbjct: 3176 ATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3232



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 4376 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4432

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 4433 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 4483

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 4484 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 4532



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 44/159 (27%), Positives = 70/159 (44%), Gaps = 8/159 (5%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C   G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 1662 ECNAAGNPSPILTWLKDGVPVKANDNFRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 1718

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  I
Sbjct: 1719 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 1776 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 1812



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 52/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 1238

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
             TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 1239 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 1296

Query: 521  RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W  +G  +    P + I  +G  + L I      D   Y C A N AG+T  +  L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEEG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 14/157 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA----EISVK 3137
            I WF +G  +E++  IR +   G   L+IL  +  ++G YSC ATN+ G+     E+ V 
Sbjct: 2608 ITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVY 2665

Query: 3138 L-ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +   ++K     P  +   + ++ +K   +   EC    +  P   + WY +GQP++   
Sbjct: 2666 IPPIINKGDLWGPGLSP--KEVK-IKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDD 2720

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +   ++ G   L I   Q  D+G Y C A N  GED
Sbjct: 2721 HVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGED 2755



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 62/288 (21%), Positives = 105/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 4079 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 4133

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 4134 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 4193

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 4194 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 4251

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 4252 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 4304

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +  +G++ V+ P
Sbjct: 4305 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVKEP 4349



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 3459 ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 3516

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 3517 SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 3570

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 3571 PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 3609



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 11/160 (6%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G  + +I+W  +GK I +    R   +     L I G  T+D+G Y+C ATN  G+ +  
Sbjct: 3273 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3332

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
             ++ +      +G K      +  ++      S + EC       P  +I W  NG P+ 
Sbjct: 3333 FNLNVYVTPTIRGNKDEAEKLMTYVD-----TSINIECRXTGTPPP--QINWLKNGLPLP 3385

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             S+ I+ ++     V+ I   Q  D   Y C A N+ G D
Sbjct: 3386 LSSHIRLLA--AGQVIRIVRAQVSDVAVYTCVASNRAGVD 3423



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 38/132 (28%), Positives = 59/132 (44%), Gaps = 6/132 (4%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           + ES + +L I  VTLSD G   C+A + +G    Q   +V E      P  ++  + + 
Sbjct: 476 LKESASVSLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE-----PPPVIQVPNNVT 530

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V  GE  VL    +      +TWQ++   +      RI T    S L++   K +DA  Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEY 589

Query: 562 QCTAQNVAGSTA 573
            C   +  GS+A
Sbjct: 590 HCMVSSEGGSSA 601



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 52/203 (25%), Positives = 79/203 (38%), Gaps = 17/203 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +L+IL T+ TD G Y C A N  G A+   ++ +       G K    T + N       
Sbjct: 2928 ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN------- 2980

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                  C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C
Sbjct: 2981 NFISLTCEVSGFPPPDLS--WLKNXQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTC 3036

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----E 3280
             A N  GE   + ++  Y    +     +  S+  +RE  S+    +     P      +
Sbjct: 3037 IAINXAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK 3096

Query: 3281 PPKFITQIQDVTKLVEGQSAHFE 3303
              + IT+   V  L +GQ  H +
Sbjct: 3097 NGRMITESTHVEILADGQMLHIK 3119



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 3729 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 3785

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 3786 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 3840

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 3841 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 3884



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 64/257 (24%), Positives = 97/257 (37%), Gaps = 22/257 (8%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P + W +K +P++  +   +R    +G   L I      D   Y+C A N  G A 
Sbjct: 2223 GIPPPNLIWKKKGSPVLTDSMGRVRI--LSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2280

Query: 157  ----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
                  VYI+P                R  S ++E +  G    T    +    +    G
Sbjct: 2281 KEYNLQVYIRPT-ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG 2339

Query: 213  TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES-DVQISTEIDRSLGPVSPPKIA-- 269
             +            E  +L+  +   S T RYV  + +V   T+    L   +PP I   
Sbjct: 2340 VEILD---------EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2390

Query: 270  -QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             + P N  + E        + SG P P  TWFK+G  +  SN   I++      LR+  T
Sbjct: 2391 HRSPENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRILS--GGRMLRLMQT 2448

Query: 329  QKSDSGHYTLLAENPNG 345
               D+G YT +  N  G
Sbjct: 2449 TMEDAGQYTCVVRNAAG 2465



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 74/296 (25%), Positives = 119/296 (40%), Gaps = 52/296 (17%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   + WY +G+ L+      + ++ G  TL + +    D+G YTC A N  GE      
Sbjct: 2703 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGEDELDFD 2760

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            V            Q P   + L +I N+ D             TGR  E     KD++ I
Sbjct: 2761 V----------NIQVPPSFQKLWEIGNMLD-------------TGRNGEA----KDVI-I 2792

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +     + E +  P       + W+ +G  + +S ++  +   G  VL+I   K  D+G 
Sbjct: 2793 NNPISLYCETNAAPPP----TLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGR 2846

Query: 3121 YSCRATNKWGQAEISVKLE-----CVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
            Y+C A N+ G+  +   +       ++ +    P   T + N       +SA  EC  + 
Sbjct: 2847 YTCVAVNEAGEDSLQYDVRVLVPPIIEGANSDLPEEVTVLVN-------KSALIEC--LS 2897

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               P  +  W  +GQP+      K +S+    +L I  TQ  D G YVC A N  G
Sbjct: 2898 SGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAG 2951



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 260  LGPVSPPKIAQKP--RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
            L  + PP I  +    + K++E        +++GNP P +TW K+GQ L     H II+ 
Sbjct: 2473 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS- 2531

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                 L++ N Q   +G YT LA +P G
Sbjct: 2532 -GGRFLQITNVQVPHTGRYTCLASSPAG 2558



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 86/218 (39%), Gaps = 35/218 (16%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            ++ IK       E     I  ++L   W KDG+P+++   +    N G+  L IK   + 
Sbjct: 2684 EVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQIS 2739

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEV 1037
            D G YTC A N  G+     ++ I          Q P   +K+  + +     +  E + 
Sbjct: 2740 DTGRYTCVASNIAGEDELDFDVNI----------QVPPSFQKLWEIGNMLDTGRNGEAKD 2789

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD 1097
             I   P                S + E    P   LT    WY +G  +TS++++     
Sbjct: 2790 VIINNP---------------ISLYCETNAAPPPTLT----WYKDGHPLTSSDKVLILP- 2829

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             G   L I   + ED+G YT VA N AGE  L   + V
Sbjct: 2830 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV 2866



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 66/168 (39%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 4013 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4070

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 4071 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 4122

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L IA+ Q  D+G Y C A N  G   T   +  +
Sbjct: 4123 SIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4167



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 4376 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 4432

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 4433 MSLTLQSPPIITLE 4446



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG P+T+S ++  I   G V L I   + EDAG YT  AVN+ GE      
Sbjct: 2806 PPPTLTWYKDGHPLTSSDKVL-ILPGGRV-LQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2863

Query: 860  IRVAARSTVT-ADLGIPEQ 877
            +RV     +  A+  +PE+
Sbjct: 2864 VRVLVPPIIEGANSDLPEE 2882



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 3177 TGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3236

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 3237 YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 3288

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 3289 ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3338



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   N   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 4349 PPVFKGDYPSNWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 4405

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 4406 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4446



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 1311

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 1312 PGISILEEG-TLLVIASVTPYDNGEYICVAVNEAG 1345



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            ++   EC++  +  P   V W  +G PL+ K +   I D G++ +    ++  D+G Y+C
Sbjct: 2309 KSISLECEVQGIPPPT--VTWMKDGHPLI-KAKGVEILDEGHI-LQLKNIHVSDTGRYVC 2364

Query: 4049 RATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEK 4086
             A N+ GM + K  +     P I+ + + P+++  +EK
Sbjct: 2365 VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2402



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 60/267 (22%), Positives = 105/267 (39%), Gaps = 13/267 (4%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            L GNP P   W +  A L++    ++R      D SL I+++   D GEYTC A N  G 
Sbjct: 914  LAGNPIPERRWIKNSAMLLQNPYITVR-----SDGSLHIERVQLQDGGEYTCVASNVAGT 968

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               +  +                    +  T+  KA G    +   S++ + ++ ++   
Sbjct: 969  NNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF 1028

Query: 215  HSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEI-DRSLGPVSPPKIAQKP 272
             +  D    V + E     E     + T  Y  +  VQ++  +  R  G +       KP
Sbjct: 1029 SAGADGSLYVVSPEGEESGEYVCTATNTAGYA-KRKVQLTVYVRPRVFGDLRGLS-QDKP 1086

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKS 331
                +  G +     ++   P P +TW K  Q +   S +H  + + +   +++  T+ S
Sbjct: 1087 VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTS 1143

Query: 332  DSGHYTLLAENPNGCIVTSGYLAVESP 358
            DSG Y  +A N  G +  +  L V  P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVP 1170



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRI-LALTSTQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 2104 PNIMGEEQN 2112



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 18/164 (10%)

Query: 3079 SMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            S  + W+ +G+ +++   +  + A G   L+I   + +D+G Y+C A+N  G+ E+   +
Sbjct: 2704 SASLSWYKDGQPLKSDDHVN-IAANGHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDV 2761

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV--PVD-------DPDMKIEWYHNG 3189
                    QK      I N+  L  G++   +  ++  P+         P   + WY +G
Sbjct: 2762 NIQVPPSFQK---LWEIGNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDG 2816

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+  S ++  +   G  VL I   +  D+G Y C A N+ GED
Sbjct: 2817 HPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGED 2858



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  +  N     GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 4349 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 4403

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 4404 SLAIYGTVNEDAGDYTCVATNEAG 4427



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  N   I  SHR R   + G + ++    K  D+G Y C A+N  G  + 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQ 692

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            +  L  ++  K         +Q+   +  G     EC    +  P +K  W+     +R 
Sbjct: 693  NSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGIPPPQVK--WFKGDLELRP 744

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLE 3250
            ST +  + D    +L I  TQ+ D+G+Y C A N+ G    + T++  G   V+++
Sbjct: 745  STFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD-VGSPPVFIQ 797



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 1170 PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 1268

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 1269 ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 1308

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 1309 GREPGISILEEGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 1368 SNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 2/75 (2%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 3256 DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 3313

Query: 1379 DSGVYTCQATNQLGE 1393
            D+G YTC ATN  GE
Sbjct: 3314 DTGKYTCVATNPAGE 3328



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 4079 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 4132

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 4133 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4165



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 15/197 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D   PP    V  ++  ++ G+ A     +I   D ++   W  N + +  +   R +  
Sbjct: 515  DVSEPPPVIQVPNNVT-VTPGERAVLTCLIISAVDYNLT--WQRNDRDVRLAEPAR-IRT 570

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               + LE+   K  D+G Y C  +++ G +  SV L        Q+P   T +   +   
Sbjct: 571  LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV------QEPPKVTVMPKNQSFT 624

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             G      C+      P  KI W  N   +  S R +  SD    + + A     D+G Y
Sbjct: 625  GGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAA---PKDAGIY 679

Query: 3223 VCRAYNKYGEDFTRATI 3239
             C A N  G D   +T+
Sbjct: 680  GCLASNSAGTDKQNSTL 696



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PP    +P   +   G      C  TG+PKP++ W +N   IV   RY++T DG
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 58/262 (22%), Positives = 96/262 (36%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 4195 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 4250

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 4251 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 4301

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V              P      P N  
Sbjct: 4302 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPPVFKGDYPSNWI 4361

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 4362 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 4418

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 4419 TCVATNEAGVVERSMSLTLQSP 4440



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 4430 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4489

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 4490 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 4545

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 4546 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4588



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGK 875



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 57/245 (23%), Positives = 96/245 (39%), Gaps = 37/245 (15%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++++  N     E     +  P   + W ++G P+++ + +    + G+  L +K    
Sbjct: 2683 KEVKIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQI 2738

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G YTC A N  GE      + +Q   S Q        L +I  + D+ R    +DV 
Sbjct: 2739 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ-------KLWEIGNMLDTGRNGEAKDVI 2791

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +            N P  L         C     P P +   WY +G  L S  +     
Sbjct: 2792 I------------NNPISL--------YCETNAAPPPTL--TWYKDGHPLTSSDKVLILP 2829

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQY 1957
              G   L I     ED+G YTC A+N  G+   S++ +V+     I +  +    E++  
Sbjct: 2830 --GGRVLQIPRAKVEDAGRYTCVAVNEAGE--DSLQYDVRVLVPPIIEGANSDLPEEVTV 2885

Query: 1958 LEDDS 1962
            L + S
Sbjct: 2886 LVNKS 2890



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 756  LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 809

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 810  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 869

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 870  ENQFGKIQSETTVTVTG 886



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 789  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 849  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +    G  I  E  ++ +  PT  + W+K+G  +   ++   I   G+I L + ++++ D
Sbjct: 2303 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSD 2358

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
            +G Y C AV+  G+ + K  L V    +I    + PE +  +++
Sbjct: 2359 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2402



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 3653 VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3710

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 3711 NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 3760

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 3761 YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 3802



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 3897 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 3953

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 3954 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 3997



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 38/167 (22%), Positives = 66/167 (39%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV      +L++      D+G YSC+A N  G ++  
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVN--NGKILKLFRATPEDAGRYSCKAINIAGTSQKY 1443

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +         F   +  +      +    EC V     PD  I W+ +G+P+   
Sbjct: 1444 FNIDVLVPPTIIGTNFPKEVSVVL----NRDVALECQVKGTPFPD--IHWFKDGKPLFLG 1497

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 1498 DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  EC+   V      + W+KNG+ +T       + D G + L I     
Sbjct: 3068 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3123

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 3124 SDTGQYVCRAINVAGRDDKNFHL 3146



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 4253 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 4307

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 4308 VN--GHSELVIERVSKEDSGTYVCTAENSVG 4336



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     S+ +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 4346 VKEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 4401

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 4402 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 4446



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     ED+G YT
Sbjct: 4365 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4419

Query: 1385 CQATNQLGEAVTSCALRVIAKKDLILE 1411
            C ATN+ G    S +L + +   + LE
Sbjct: 4420 CVATNEAGVVERSMSLTLQSPPIITLE 4446



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 4365 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4419

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 4420 CVATNEAGVVERSMSLTLQS 4439



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    + KN  F  G          G P P ++WT     +V  ++Y M     T D +
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM-----TSDGT 665

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L IK   P D G Y C A N  G
Sbjct: 666 LFIKNAAPKDAGIYGCLASNSAG 688



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I +  G     E  ++ I   T  V W+KDG P+  +  +    + G++ L +K++ V 
Sbjct: 2302 EIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI-LQLKNIHVS 2357

Query: 978  DAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            D G Y C A N  G      +L++     II   + P  +  ++
Sbjct: 2358 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2401



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G  +L I  V   DAGHYTC A N  G ++TS  LT+
Sbjct: 4111 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4166



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 13/203 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C ATN  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 1135 MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 1188

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 1189 DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 1244

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP-KFIT 3286
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P  K++ 
Sbjct: 1245 NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302

Query: 3287 QIQDVTKLVEGQSAHFEARLVPV 3309
              +++T    G S   E  L+ +
Sbjct: 1303 NGRELTGREPGISILEEGTLLVI 1325



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 1252 TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 1305

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 1306 ELTGREPGISILEEGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 1365 EQVSNVSVLLNQLTNLFCEVEGTPSPII 1392



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265  PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 3620 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 3677

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++ N    D+ +YT +A N  G       L V  P
Sbjct: 3678 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 3713



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 4365 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4419

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 4420 CVATNEAGVVERSMSLTLQSPPIITLE 4446



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 4373 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4429

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 4430 ERSMSLTLQSPPIITLE 4446



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 82/359 (22%), Positives = 144/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 1371 SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDA 1426

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST---QNEAGLEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +    +    L +   LE + K      + 
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPKEVSVVLNRDVALECQVKGTPFPDIH 1486

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 1487 WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 1545

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C+       A+T    G  I+ S +++Y++      
Sbjct: 1546 PSIKGGNVTTDI-SVLINSLIKLECKTRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 1604

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 1605 IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 1663

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++      + G   L +      D G Y C A +  GE
Sbjct: 1664 NAAGNPSPILTWLKDGVPVKANDNFRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 36/159 (22%), Positives = 63/159 (39%), Gaps = 10/159 (6%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            WF +G  +  S+ +R +   G  +L ++ T   D+G Y+C   N  G+      L  +  
Sbjct: 2421 WFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL-- 2476

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
                 P        +E +K  +      T     +P  +I W+ +GQP++       +S 
Sbjct: 2477 ----VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISG 2532

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
              F  L I   Q   +G Y C A +  G      ++N +
Sbjct: 2533 GRF--LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVF 2569



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632  RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 3430 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 3486

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
              G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 3487 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3538



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 3462 GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 3519

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 3520 FILKVLEPPHINGSEEHE 3537



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 3548 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3605

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 3606 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 3656

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 3657 LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 3701



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 3710 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 3767

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 3768 F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3807



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 4261 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4301



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 633  VYPPPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            V+ PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   
Sbjct: 2961 VHVPPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNXQPIKLNTN--TLIVP 3016

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            G  +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 3017 GGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTV 3053



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 1216

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 1217 HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 1256



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEEG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 1351 YNLKVHVPPVIKDKEQ-------VSNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 1400

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 1401 VTESSTIQTVNN--GKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I V  G  +  +C V+ +  PT  + W  +G P      V  L++ G I L +  I+  D
Sbjct: 2303 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GHI-LQLKNIHVSD 2358

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
             G Y C A N  G       ++  A   I+   + P+ +S
Sbjct: 2359 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENIS 2398



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 3243 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 3300

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+    
Sbjct: 3301 NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTYV 3357

Query: 1960 DDS 1962
            D S
Sbjct: 3358 DTS 3360



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 3262 GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3319

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 3320 CVATNPAG 3327



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 4076 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 4132

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 4133 --SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4172



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV + P+ +    N     G+ V + C     G    ++ W  N   I   HR+R   +
Sbjct: 606  LTVQEPPKVTVMPKNQSFTGGSEVSIMC--SATGYPKPKIAWTVNDMFIVGSHRYRMTSD 663

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI-AKKDLILESQHPSGLEKIQY 1423
                 L + +  P+D+G+Y C A+N  G    +  LR I A K ++++S+    L  I  
Sbjct: 664  G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITV 720

Query: 1424 LE 1425
            +E
Sbjct: 721  ME 722



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 714 ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 769

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 770 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 826

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 881

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 938

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAG 967



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T    + S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 1439 TSQKYFNIDVLVPPTIIGTNFPKEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 1496

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 1497 GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 2034 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSTQISDTGRYTCVAVNAAGEK 2092

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 2093 QRDIDLRV 2100



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 4/119 (3%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V  GK+   EC+V+ +  P   + +  +G  L  A    I  D G++ L +++    D G
Sbjct: 2305 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTG 2360

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVT 2372
             Y   A+N  G       ++V A  SII   + PE +  + +   +   +   IP P T
Sbjct: 2361 RYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPST 2419



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 48/170 (28%), Positives = 72/170 (42%), Gaps = 20/170 (11%)

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDI---------IDESVTIKPRFVTRPKSIE 1454
            AK   IL+  H   L+ I ++ DT RY    +          D SV   P  +   +S E
Sbjct: 2337 AKGVEILDEGHILQLKNI-HVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE 2395

Query: 1455 N--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            N  V+E   V   C+   +   +    WFK+G PV++ +  R +   G   L ++    E
Sbjct: 2396 NISVVEKNSVSLTCEASGIPLPS--TTWFKDGWPVSLSNSVRILS--GGRMLRLMQTTME 2451

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            D+G YTC   N  G +     L+      IV     E  LE ++V E +S
Sbjct: 2452 DAGQYTCVVRNAAGEERKIFGLSVLVPPHIV----GENTLEDVKVKEKQS 2497



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            W KDG PV  S+ +      G   L +   T+ DAG YTC   NA G+      L+++  
Sbjct: 2421 WFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP 2478

Query: 1005 KDIIAES 1011
              I+ E+
Sbjct: 2479 PHIVGEN 2485



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   V  EC  E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 3072 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3127

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 3128 QYVCRAINVAGRD 3140



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LEC    +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 3072 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 3127

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 3128 QYVCRAINVAG 3138



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 4377 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4433

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 4434 SLTLQS 4439



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 63/283 (22%), Positives = 112/283 (39%), Gaps = 22/283 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 1225

Query: 131  LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
            L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285

Query: 188  H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                A GT        + T K  + NG + +  +       E  LL   S        Y+
Sbjct: 1286 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEEGTLLVIASVTPYDNGEYI 1337

Query: 246  GESDVQI-STEIDRSLGPVSPPKIAQKPRNSKLQEGAD--AQFQVQLSGNPRPRVTWFKN 302
              +  +  +TE   +L    PP I  K + S +    +       ++ G P P + W+K+
Sbjct: 1338 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVSNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 1397

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 1398 NVQVTESS--TIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 1575 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 860  IRVAARSTVTADLGIPEQRRYI 881
            + V     +  +L  P  ++ +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVV 1654



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 1579 ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 1635

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +   +  
Sbjct: 1636 YVPPMIEGNLATPLN--KQVVIAHSLTLECNA--AGNPSPILTWLKDGVPVKANDNFRI- 1690

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 1691 -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ +   +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1946 GNPVPVITWYKDNCLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 2003

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 2004 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 2053

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +  TQ  D+G Y C A N  GE
Sbjct: 2054 SFSNGLQVLS--GGRILALTSTQISDTGRYTCVAVNAAGE 2091



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G+ +  EC+++ +      V W K+G P+ I  +   I D G++ L + ++   D+G
Sbjct: 2305 VTRGKSISLECEVQGIPPPT--VTWMKDGHPL-IKAKGVEILDEGHI-LQLKNIHVSDTG 2360

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             Y C AVN+ G  +    L+  +   I+    N    E I V+E  S
Sbjct: 2361 RYVCVAVNVAGMTDKKYDLSVHAPPSII---GNHRSPENISVVEKNS 2404



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G++   E ++  +  PT  V W KDG P+  +  +  I + G++ L + ++   D G Y 
Sbjct: 2308 GKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGV-EILDEGHI-LQLKNIHVSDTGRYV 2363

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
              AVN  G       + V A  ++  +   PE    +EK
Sbjct: 2364 CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2402



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   EC     P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 3074 EGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3129

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 3130 VCRAINVAGRDDKNFHLNVYVPPSI 3154



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 3245 PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 3302

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 3303 STLNIYGALTSDTGKYTCVATNPAG 3327



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 3275 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3328



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 788  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 845  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 900

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 901  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 956

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 957  EYTCVASNVAG 967



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEEGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 1351 YNLKVHVPP 1359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 36/151 (23%), Positives = 62/151 (41%), Gaps = 11/151 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +  T+ +D+G Y+C A N  G+ +  + L   
Sbjct: 2043 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSTQISDTGRYTCVAVNAAGEKQRDIDLRVY 2101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 2102 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 2152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            S+    VL I   Q  D+G Y C A N  G+
Sbjct: 2153 SE-NRSVLKIEDAQVQDTGRYTCEATNVAGK 2182



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 4373 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4429

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 4430 ERSMSLTLQS 4439



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 4376 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4432

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 4433 MSLTLQSPPIITLE 4446



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 87/402 (21%), Positives = 156/402 (38%), Gaps = 41/402 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 791  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 847

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 908  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 966

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 967  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 1023

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 1024 SSAKFSAGADGSLYVVSPEGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDLRGLS 1082

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 1137

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +    DSG+Y C A N+ G    + +L       I R  ++
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 1544 IPPSIKGGNVTTDI----SVLINSLIKLECKTRGLPMP--AITWYKDGQPIMSSSQALYI 1597

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 1598 -DKG-QYLHIPRAQVSDSATYTCHVANVAG 1625



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 2063

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 2064 GGRI-LALTSTQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 18/155 (11%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 3068 SVVNVREGTSVSLECESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 3123

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 3124 SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 3171

Query: 3548 LTPEAESGNPPEFTTTPSDLILSENSSAHFECRLI 3582
            LT +A +G PP       +    ENS +  E R++
Sbjct: 3172 LTCDA-TGIPPPTIAWLKNYKRIENSDS-LEVRIL 3204



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 3258 SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3315

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++    D S
Sbjct: 3316 GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTYVDTS 3360



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S      G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 4346 VKEPPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 4400

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 4401 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4438



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL+L+S   +   +   +  S        V + V + P+ +T +      + G      C
Sbjct: 575  SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMC 633

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P  ++ W  N   +   HRYR ++D     L I     +D+G Y C A N+ G
Sbjct: 634  SATGYPKP--KIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG 688

Query: 1927 QAVSSIRLN-VQSKESIIRDSQHESALEKIQYLE 1959
                +  L  +++ + ++  S+   AL  I  +E
Sbjct: 689  TDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 897  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 952

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 953  QDGGEYTCVASNVAG 967



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 1224

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
             +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 1225 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 1265



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+   R + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNFR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 1725 YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLIDE 1777

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 1778 RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 1813



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/149 (21%), Positives = 60/149 (40%), Gaps = 7/149 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            SH   I+   G +I  EC V+    PT  + W  +  PL      +   D  ++ L + +
Sbjct: 2298 SHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKN 2353

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
             +  D+G Y C A N  G       L      +I  + + P+    +  VE+   +   +
Sbjct: 2354 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPE---NISVVEKNSVSLTCE 2410

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVEG 2926
                 +P T + K  W + ++   +++ G
Sbjct: 2411 ASGIPLPSTTWFKDGWPVSLSNSVRILSG 2439



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 54/211 (25%), Positives = 82/211 (38%), Gaps = 34/211 (16%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            S K V+IK       E     +  A+L   WY + +PLKS        N G   L I   
Sbjct: 2681 SPKEVKIKVNNTLTLECEAYAIPSASLS--WYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2736

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSA 1702
               D+G YTC         V S IA    +    +  Q   +  +L ++ +     R+  
Sbjct: 2737 QISDTGRYTC---------VASNIA-GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2786

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
              +VI   P+           E  AA           P   + W ++G P+ +S+++  +
Sbjct: 2787 AKDVIINNPISLY-------CETNAA-----------PPPTLTWYKDGHPLTSSDKVLIL 2828

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G   L +     ED+G YTC A+NE GE
Sbjct: 2829 P--GGRVLQIPRAKVEDAGRYTCVAVNEAGE 2857



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633  VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 3053 VYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTH-VEI 3109

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
               G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 3110 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 3155



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 3072 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 3127

Query: 842  SYTVRAVNKLG 852
             Y  RA+N  G
Sbjct: 3128 QYVCRAINVAG 3138



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 3262 GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3319

Query: 1252 VRAVNHLG 1259
              A N  G
Sbjct: 3320 CVATNPAG 3327



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS+ I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 4349 PPVFKGDYPSNWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 4404

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 4405 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 4462

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 4463 QATGEPQPTIT 4473



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ I+     + +     +V  I   + +++G Y C A N  G    
Sbjct: 1759 TGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKK 1816

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 1817 EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 1865

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 1866 PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 724  AVLHVTPRATIE 735
              LHV    ++E
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSTQIS--DTGRYTCVAVNAAGEKQR 2094

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 2095 DIDLRVYVPPNIMGEEQNVSVL 2116



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P+++I++   S   EC +  +   +  V W  +G PL+    V+ +++ G  IL++  ++
Sbjct: 2300 PTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDE-GH-ILQLKNIH 2355

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSH 3664
              D G Y C A N  G       L V     II   + P +
Sbjct: 2356 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2396



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 8/100 (8%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKI--HFETRIE----PVGDPTMKIEWLKNGQSI 679
            P GEEDR++    ++ P       E  K+  + +T I       G P  +I WLKNG  +
Sbjct: 3325 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTYVDTSINIECRXTGTPPPQINWLKNGLPL 3384

Query: 680  EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
              SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 3385 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 3422



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 785  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 843

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 844  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 1006 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPEGEESGEYVCTATNTAGYAKRK 1063

Query: 724  AVL--HVTPR 731
              L  +V PR
Sbjct: 1064 VQLTVYVRPR 1073



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 54/270 (20%), Positives = 93/270 (34%), Gaps = 18/270 (6%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 1102 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATNIAG 1157

Query: 154  EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
                +V +                        +   A GT       S+    +   +G 
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 1216

Query: 214  DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
             H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 1217 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 1269

Query: 272  PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
            P N+  QE    Q   F     G P+P + W  NG+ L    +  I      T L + + 
Sbjct: 1270 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEEGTLLVIASV 1328

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               D+G Y  +A N  G       L V  P
Sbjct: 1329 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 1358



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTV-NNGKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 860  IRVAARSTV 868
            I V    T+
Sbjct: 1446 IDVLVPPTI 1454



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            +++  + V   P      + PT++  + G+S   EC ++  P P   V W  +G  L   
Sbjct: 2280 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKA 2337

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                  ++     L +  ++  D+G Y C A+N  G       L+V +  SII    H S
Sbjct: 2338 KGVEILDEGHI--LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII--GNHRS 2393

Query: 1951 ALEKIQYLEDDS 1962
              E I  +E +S
Sbjct: 2394 P-ENISVVEKNS 2404



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +C    V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 3070 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 3125

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 3126 TGQYVCRAINVAG 3138



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 3072 VREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 3127

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 3128 QYVCRAINVAG 3138



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626  PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 3605 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 3662

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 3663 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 3710



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 4269 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 4322

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G    +G
Sbjct: 4323 DSGTYVCTAENSVGFVKATG 4342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 3529 EGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS 3588
            EG  + IA     +G   T    +E   PP     P+++ ++    A   C +I   D +
Sbjct: 494  EGFYECIAVSSAGTGRAQTFFDVSE---PPPVIQVPNNVTVTPGERAVLTCLIISAVDYN 550

Query: 3589 MRVEWFHNGKP--LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            +   W  N +   L   +R++T+ +     LE+  V   DAG Y C  ++  G +  S  
Sbjct: 551  LT--WQRNDRDVRLAEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVF 605

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTE 3670
            L V+    + + P+  S F  G+E
Sbjct: 606  LTVQEPPKVTVMPKNQS-FTGGSE 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PPK     K+ +      V   C       PK +I W  N   +   HRYR   D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGY--PKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              +L I     +D+G Y C A N  G D   +T+   + P +++
Sbjct: 664  -GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 916 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 972

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 973 TSVVVHVLP--TIQHGQQILSTIEGI 996



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+      +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 1454 IIGTNFPKEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 1510

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P+  + WLK+G  ++A+  F      G   L+++S    D G+Y C A S  G  E K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNFR--IEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIK 1724

Query: 724  AVLHVTPRATIE 735
              + V     IE
Sbjct: 1725 YEVDVLVPPAIE 1736



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)

Query: 1405 KKDLILESQ-HPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            +K +I ++Q   +GL +         +KK    + +V + P   +   S   V++ + V 
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVA 1845

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
             +C    +   N  + W K+ QPV        I   G V L I   + ED+G YTC A N
Sbjct: 1846 LQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902

Query: 1524 LVGTDEVSCRL 1534
              G  +   +L
Sbjct: 1903 AAGETQQHIQL 1913



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 83/375 (22%), Positives = 142/375 (37%), Gaps = 32/375 (8%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            +NI V E   V   C  E  G P     WF +G P +  + V  L+  G   L +     
Sbjct: 2395 ENISVVEKNSVSLTC--EASGIPLPSTTWFKDGWPVSLSNSVRILS--GGRMLRLMQTTM 2450

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+YTC   N  G       ++      IV E+ L      EK        ++  P  
Sbjct: 2451 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2510

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E       + + + ++H +    G RF  ++   + P      Y      P+GH+ R+  
Sbjct: 2511 EITWHKDGQPLQEDEAHHI--ISGGRF-LQITNVQVP--HTGRYTCLASSPAGHKSRSFS 2565

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVND------FGEDFTKATISCKKLPDIILQNQVPR- 3935
               FVS  I  V ++ + E +   +N           +  ATI+  K    +  N+  R 
Sbjct: 2566 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI 2625

Query: 3936 --GMKRSEALTQMEATIKKYTSEVYLTEDDL---YDVDKKQPP------RFVTQIQSQTS 3984
              G +  + L   E    +Y+        ++   Y+V    PP       +   +  +  
Sbjct: 2626 LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEV 2685

Query: 3985 LVEMETT-KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
             +++  T   EC+   +  P+  + W+ +G+PL   +    I   G+  +        D+
Sbjct: 2686 KIKVNNTLTLECEAYAI--PSASLSWYKDGQPLKSDDHVN-IAANGH-TLQIKEAQISDT 2741

Query: 4044 GEYLCRATNLYGMDE 4058
            G Y C A+N+ G DE
Sbjct: 2742 GRYTCVASNIAGEDE 2756



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 798  SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            S P   + W+KDG P+ ++  I  +   G  +L I++ + ++AG Y+  A N+ GE I  
Sbjct: 2602 SYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2659

Query: 858  ASIRV 862
              ++V
Sbjct: 2660 YEVKV 2664



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+G  L +   ++     G  TL I + + D++G Y+C ATN  GE +    
Sbjct: 2604 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2661

Query: 2732 IKI 2734
            +K+
Sbjct: 2662 VKV 2664



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +C    V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 3068 SVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3123

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 3124 SDTGQYVCRAINVAG 3138



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 20/65 (30%), Positives = 28/65 (43%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 3273 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3332

Query: 997  ANLTI 1001
             NL +
Sbjct: 3333 FNLNV 3337



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 3275 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3334

Query: 860  IRVAARSTV 868
            + V    T+
Sbjct: 3335 LNVYVTPTI 3343



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 3830 GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 3887

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 3888 RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 3946

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 3947 ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 3999

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 4000 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 4057

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 4058 MCVAQNPAGTALGKIKLNVQVP 4079



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 4072 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 4127

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 4128 VLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4166



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 791  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 850  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 883



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 4/88 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 994  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPEGEESGEY 1049

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRD 1945
             C A N  G A   ++L V  +  +  D
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGD 1077



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P ++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 1446 IDVLVPPTIIG-----TNFPKEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 1496

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 1497 GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 3/83 (3%)

Query: 265  PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PP I     P+   +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 1451 PPTIIGTNFPKEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 1509

Query: 323  LRVRNTQKSDSGHYTLLAENPNG 345
            L ++N +++D G Y     N  G
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAG 1532



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 39/159 (24%), Positives = 65/159 (40%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 1907

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY +   +
Sbjct: 1908 QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNCLL 1961

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1962 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1998



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 2099 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 2156

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
              + ++     +QD+G YTC A +  G  E K
Sbjct: 2157 SVLKIE--DAQVQDTGRYTCEATNVAGKTEKK 2186



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 38/179 (21%), Positives = 72/179 (40%), Gaps = 7/179 (3%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W   G  +      R     G   L+I   + +D+  YSC A+N  G A+    L+    
Sbjct: 2231 WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY-- 2288

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             +       +H   I  +  G+S   EC V  +  P   + W  +G P+  +  ++ + D
Sbjct: 2289 IRPTITNSGSHPTEII-VTRGKSISLECEVQGIPPP--TVTWMKDGHPLIKAKGVE-ILD 2344

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
             G  +L +      D+G YVC A N  G    +  ++ +    +      P++++ + +
Sbjct: 2345 EGH-ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK 2402



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E  + P  TI WF +G  + +    R     G   L IL    +++G Y C ATN+ GE 
Sbjct: 2599 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2656

Query: 2194 VNTCTLKV 2201
            +    +KV
Sbjct: 2657 IKHYEVKV 2664



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 3729 KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3784

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 3785 MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3821



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 3739 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 3796

Query: 724  AVL--HVTP 730
              L  HV P
Sbjct: 3797 IDLQVHVPP 3805



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 3741 PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3791



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 4152 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 4205

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 4206 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 4257



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 1253 EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 1304

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 1305 RELTGREPGISILEEGTL-LVIASVTPYDNGEYICVAVNEAGT 1346



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 1259 QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 1312

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 1313 GISILEEGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 1354



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ WY +G+ + S + +    + G+  L I   +  D+G YT VA N AGE +L   + +
Sbjct: 2706 SLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2763

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            +   S       + L+E          +  M       ++K V +   +NP        I
Sbjct: 2764 QVPPSF------QKLWE----------IGNMLDTGRNGEAKDVII---NNP--------I 2796

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C       PT+   W+ +G  +T  S  K     G   L I  A   D G YT  AV
Sbjct: 2797 SLYCETNAAPPPTL--TWYKDGHPLT--SSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2852

Query: 1256 NHLGSAHTSAIVRVI 1270
            N  G       VRV+
Sbjct: 2853 NEAGEDSLQYDVRVL 2867



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 3254 PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3309

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 3310 ALTSDTGKYTCVATNPAGE 3328



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 3470 WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 3527

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 3528 PHINGSEEH 3536



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 3524 VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 3581

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 3582 GEVLRISTAQVEDTGRYTCLASSPAGD 3608



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 3560 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 3607



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 3713 PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 3768

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 3769 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3801



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 4198 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4255

Query: 1134 TV 1135
            TV
Sbjct: 4256 TV 4257



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 4452 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 4507

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 4508 FECVARNLMG 4517



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 6/142 (4%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
            Q  + +   +L I++    DEG Y+C+A +SAG         V++P     +P      +
Sbjct: 474  QYLKESASVSLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVP-----NN 528

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V  G+ A     I S +   + W R    +    +   I    N  L + +    D G
Sbjct: 529  VTVTPGERAVLTCLIISAVDYNLTWQRNDRDV-RLAEPARIRTLANLSLELKSVKFNDAG 587

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C  ++  G    S  L V+
Sbjct: 588  EYHCMVSSEGGSSAASVFLTVQ 609



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  KI W  N+  +    RY+ T D +   L I +   +D+GIY C A+NS G+   + +
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 2863 LR 2864
            LR
Sbjct: 696  LR 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   PK + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNF---PKEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 1493

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284  QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
            + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 1566 KLECKTRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 1623

Query: 344  NGCIVTSGYLAVESP 358
             G    S ++ V  P
Sbjct: 1624 AGTAEKSFHVDVYVP 1638



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY     + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1952 ITWY-KDNCLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 2010 VAPSISGSN 2018



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 9/128 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            +L++     +D+G Y C A N  G  +    L      S     R   +I  +E  K+  
Sbjct: 2348 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE--KNSV 2405

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   E + +P+        W+ +G P+  S  ++ +S  G  +L +  T   D+G+Y C 
Sbjct: 2406 SLTCEASGIPLPSTT----WFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCV 2459

Query: 3226 AYNKYGED 3233
              N  GE+
Sbjct: 2460 VRNAAGEE 2467



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   + W+ +G P++     +     G   L IL A  ++ G Y C ATN  GE +    
Sbjct: 2604 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2661

Query: 2067 VKV 2069
            VKV
Sbjct: 2662 VKV 2664



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 3070 VNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 3125

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 3126 TGQYVCRAINVAGRDDKNFHLNVYVPPSI 3154



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 3440 SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 3495

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 3496 KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 3536



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 4101 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4155

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 4156 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4186



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 4102 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSS 4158

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 4159 STSTKLTVHVPPR--IRSTEGH 4178



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 4195 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 4252

Query: 997  ANLTI 1001
             +LT+
Sbjct: 4253 VSLTV 4257



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 42/146 (28%), Positives = 57/146 (39%), Gaps = 16/146 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 4218 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 4269

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 4270 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 4323

Query: 3219 SGEYVCRAYNKYGEDFTRATINCYGK 3244
            SG YVC A N  G  F +AT   Y K
Sbjct: 4324 SGTYVCTAENSVG--FVKATGFVYVK 4347



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 4376 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 4427



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK ++ W  N + I  S+R     D     L +K   P+D+G Y C A N  G    +
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693

Query: 1798 STL-FVQSKASLQLESQHESALQKIQQLE 1825
            STL ++++   + ++S+   AL  I  +E
Sbjct: 694  STLRYIEAPKLMVVQSELLVALGDITVME 722



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 775  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 15/167 (8%)

Query: 1792 GEAV-TSSTLF-VQSKASLQLES-QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFIT 1848
            GE + TSS  F   +  SL + S + E + + +    +++ Y +R+ V++ V   PR   
Sbjct: 1018 GELISTSSAKFSAGADGSLYVVSPEGEESGEYVCTATNTAGYAKRK-VQLTVYVRPRVFG 1076

Query: 1849 QLNG-----PTKLS--EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
             L G     P ++S   G+     C ++  P P   + W    +++       T    G 
Sbjct: 1077 DLRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLISPFSPRHTFLPSG- 1133

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
             ++ I      DSG Y C A N  G    +++LNV     I R  +H
Sbjct: 1134 -SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH 1179



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449

Query: 1003 TKKDII 1008
                II
Sbjct: 1450 VPPTII 1455



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 3833 ITQIKSHTVE----ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            IT   SH  E      + +  EC V+    P   + W ++G  L        + D G + 
Sbjct: 2293 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVE-ILDEGHI- 2348

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGM 3937
            L +  ++  D+G Y+C AVN  G    K  +S    P II  ++ P  +
Sbjct: 2349 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2397



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            P   + WF +G  L      R     G   L IL   E+N+G Y CVATN+ G
Sbjct: 2604 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAG 2654



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            DV    P+   C       PT+   W+ +G P  +  +V  L   G   L I      DA
Sbjct: 2789 DVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDA 2844

Query: 3766 GEYTCRATNKWG 3777
            G YTC A N+ G
Sbjct: 2845 GRYTCVAVNEAG 2856



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 3183 TIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3242

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 3243 QVPPSVAGAEI 3253



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 3527 PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 3582

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 3583 EVLRISTAQVEDTGRYTCLASSPAG 3607



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 3630 RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 3686

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 3687 -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 3745

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 3746 TWRKDGAVLAGNHARYSILENGFLHI---QSAH 3775



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L IA V+  D+G YT +A N AG +  S  +TV 
Sbjct: 4111 ITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4167

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 4168 VPPRIRSTEGHYTVNENSQAI 4188



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 4377 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4433

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 4434 SLTLQSPPIITLE 4446



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/106 (21%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP + Q P N  +  G  A     +       +TW +N + +  +    I T  N  +L 
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLE 577

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
           +++ + +D+G Y  +  +  G    S +L V+ P +  V  +   +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSF 623



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 790  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 847  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 897  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 951

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 952  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 994  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPEGEESGEY 1049

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T   +  +  +    +G+S +K  E+      +      + S 
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYVRPRVFGDL---RGLSQDKPVEISVLAGEEVTLPCEVKSL 1106

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 1107 PPPIITWAK 1115



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 1236

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQE 1260



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 1485 IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC   +  G AE  
Sbjct: 1573 GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCHVANVAGTAEKS 1630

Query: 724  AVLHVTPRATIERTSQHPETLQYI 747
              + V     IE     P   Q +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVV 1654



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+    F+   + G   L+I+ A   
Sbjct: 1650 NKQVVIAHSLTLECNAA--GNPSPILTWLKDGVPVKANDNFRI--EAGGKKLEIMSAQEI 1705

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 2039 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSTQISDTGRYTCVAVNAAGEKQRDID 2097

Query: 860  IRV 862
            +RV
Sbjct: 2098 LRV 2100



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P+  + WYKDG+P+ +   +    N G+ +L I   +  D G YT  A N  GE
Sbjct: 2703 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASNIAGE 2754



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG P+ +S ++      G   L I    V DAG YTC A N  G+ +   ++ ++
Sbjct: 2812 WYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2867



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+ N++EG     EC    +  P +T  W+ NG+ I          D G + L I     
Sbjct: 3068 SVVNVREGTSVSLECESNAVPPPVIT--WYKNGRMITESTHVEILAD-GQM-LHIKKAEV 3123

Query: 2177 EDSGTYMCKATNKLG 2191
             D+G Y+C+A N  G
Sbjct: 3124 SDTGQYVCRAINVAG 3138



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 3450 KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 3505

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 3506 TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3537



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 3713 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 3770

Query: 325  VRNTQKSDSGHYTLLAENPNG 345
            +++   +D+G Y  +A N  G
Sbjct: 3771 IQSAHVTDTGRYLCMATNAAG 3791



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 4107 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4163

Query: 860  IRV 862
            + V
Sbjct: 4164 LTV 4166



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 4365 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 4419

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 4420 CVATNEAGVVERS 4432



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 4371 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4427

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 4428 VVERSMSL 4435



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 4377 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4433

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 4434 SLTLQSPPIITLEPVE 4449



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKI 876



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+   +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1946 GNPVPVITWYKDNCLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 2003

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 2004 YSLQVHVAP 2012



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 3148 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSG 3206

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
               L +      DSG YTC A +  G A+
Sbjct: 3207 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 3235



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 3262 GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3319

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 3320 CVATNPAGEEDRIFNLNV 3337



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 3275 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3328



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 4105 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTS 4161

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 4162 TKLTVHVPPRIRSTEGHYTVNENSQAI 4188



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP--FATGSR 3743
            T  D    PP   +++ +N+ V  G      C +    D    + W  N R    A  +R
Sbjct: 512  TFFDVSEPPP--VIQVPNNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEPAR 567

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            + TL +   ++L++  +   DAGEY C  +++ GS+  +  +T
Sbjct: 568  IRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLT 607



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 700  EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 754

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 755  GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 798



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 1181 KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 1236

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTV 1264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 1/87 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G     
Sbjct: 1292 GTPKPTIKWLHNGRELTGREPGISILEEGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 1350

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
              L V     ++ + Q  +    + QL
Sbjct: 1351 YNLKVHVPPVIKDKEQVSNVSVLLNQL 1377



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 1176 KPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +P      S+P    V+ GK+I LEC ++ +  PT  V W  +G  +      +   +  
Sbjct: 2290 RPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGH 2347

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
             + L  IH   +DTG Y   AVN  G       + V     I+ + ++ + I  ++
Sbjct: 2348 ILQLKNIHV--SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2401



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+ E QS    C +   P P   + W+ +G+ LQ    +   +   F  L I  V    +
Sbjct: 2491 KVKEKQSVTLTCEVTGNPVPE--ITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHT 2546

Query: 1915 GEYTCKAINNLGQAVSSIRLNV 1936
            G YTC A +  G    S  LNV
Sbjct: 2547 GRYTCLASSPAGHKSRSFSLNV 2568



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P D+ +  NS     C       ++  + WF +G PL +   ++ +   G   L+I    
Sbjct: 2583 PEDVTVILNSPTSLVCEAYSYPPAT--ITWFKDGTPLESNRNIRILP--GGRTLQILNAQ 2638

Query: 3624 QRDAGLYTCKATNRHGE 3640
            + +AG Y+C ATN  GE
Sbjct: 2639 EDNAGRYSCVATNEAGE 2655



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 51/193 (26%), Positives = 78/193 (40%), Gaps = 41/193 (21%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            P+  + W+ +G+P  +   V+   + G   L I      D G YTC A+N          
Sbjct: 2703 PSASLSWYKDGQPLKSDDHVNIAAN-GH-TLQIKEAQISDTGRYTCVASN---------- 2750

Query: 3785 ITCSAKRDIVLESQLPQGMSGEKIKE----LERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            I    + D  +  Q+P   S +K+ E    L+ GR  +A  ++ I++ P           
Sbjct: 2751 IAGEDELDFDVNIQVPP--SFQKLWEIGNMLDTGRNGEA--KDVIINNP----------- 2795

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
                  +   C       P L   WY++G  L S  +   +   G V L I     ED+G
Sbjct: 2796 ------ISLYCETNAAPPPTLT--WYKDGHPLTSSDKV-LILPGGRV-LQIPRAKVEDAG 2845

Query: 3901 EYICRAVNDFGED 3913
             Y C AVN+ GED
Sbjct: 2846 RYTCVAVNEAGED 2858



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            D+I++   S + E    P       + W+ +G PL +  +V  +   G  +L+I      
Sbjct: 2789 DVIINNPISLYCETNAAP----PPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVE 2842

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            DAG YTC A N  GE ++   ++V
Sbjct: 2843 DAGRYTCVAVNEAGEDSLQYDVRV 2866



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 2997 LSWLKNXQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVY 3054

Query: 1003 TKKDI 1007
                I
Sbjct: 3055 VPPSI 3059



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 3275 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3329



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 3464 PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3520

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 3521 ILKV-------LEPPHINGSEEHEEI 3539



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 3464 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 3515



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 4439 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4495

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 4496 YIADAQ---KEDTSEFECVARNLMGS 4518



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E P+     KN   T G  V +  + T    P  ++ W  N   +   HR++ T D  
Sbjct: 608  VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG- 664

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
               L I  A  +D G Y C A+N+ G     S+++
Sbjct: 665  --TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI W  N   +    R+++TSD    TL + +   +D+GIY C A N  G    +ST
Sbjct: 639  PKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 3001 V 3001
            +
Sbjct: 696  L 696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 700  EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 756

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 757  -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 794  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 853

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 854  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEEG-TLLVIASVTPYDNGEYICV 1339

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 1340 AVNEAGTTERKYNLKV 1355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 39/170 (22%), Positives = 74/170 (43%), Gaps = 10/170 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQ-SQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T +  Y++    PP    + Q S  S++  + T   C++   G P+  + W+ +   +  
Sbjct: 1346 TTERKYNLKVHVPPVIKDKEQVSNVSVLLNQLTNLFCEVE--GTPSPIIMWYKDNVQVTE 1403

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP 4078
             +    + + G +   F    PED+G Y C+A N+ G  +    I     P I+  +  P
Sbjct: 1404 SSTIQTVNN-GKILKLFR-ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTII-GTNFP 1460

Query: 4079 KHMKSIEKIREMEASWQV--TPEQVVEESKARCPPVFVSLPDAVTVEEGE 4126
            K + S+   R++    QV  TP   +   K    P+F+  P+   ++ G+
Sbjct: 1461 KEV-SVVLNRDVALECQVKGTPFPDIHWFKDG-KPLFLGDPNVELLDRGQ 1508



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 1471 VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 1527

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 1528 SNAAGKQAKDIKLT 1541



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/157 (20%), Positives = 62/157 (39%), Gaps = 6/157 (3%)

Query: 3948 ATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTS--LVEMETTKFECQLAPVGDPNM 4005
            AT   + + V  T +  + VD   PP     + +  +  +V   +   EC  A  G+P+ 
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECNAA--GNPSP 1671

Query: 4006 KVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKT 4065
             + W  +G P+   + F    + G   +        D G+Y+C AT++ G  E K  +  
Sbjct: 1672 ILTWLKDGVPVKANDNFR--IEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDV 1729

Query: 4066 TGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVV 4102
               P I    +    +  +  + E++     +P   +
Sbjct: 1730 LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 1910

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 1911 IQLHVHEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915

Query: 1136 ETRSSID 1142
                S++
Sbjct: 1916 HEPPSLE 1922



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VT G  + LE  +  +  PT  V W  +G P+ +    +   D G++ L +   +  DTG
Sbjct: 2305 VTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTG 2360

Query: 2049 TYMCKATNAVG 2059
             Y+C A N  G
Sbjct: 2361 RYVCVAVNVAG 2371



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 4/98 (4%)

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R+  NI  VE  +V L C     G       WF +G P+   +  R         L L+ 
Sbjct: 2392 RSPENISVVEKNSVSLTCEAS--GIPLPSTTWFKDGWPVSLSNSVRILSGGRM--LRLMQ 2447

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
               ED+G YTC   N  GE      L V+    ++ E+
Sbjct: 2448 TTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGEN 2485



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P     W+KDG P++ S+ +  I + G + L +M    EDAG YT    N  GE
Sbjct: 2415 PLPSTTWFKDGWPVSLSNSVR-ILSGGRM-LRLMQTTMEDAGQYTCVVRNAAGE 2466



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + W+ +G  L+S    R     G   L IL    +++G Y+C A N  G+ 
Sbjct: 2599 EAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEM 2656

Query: 1929 VSSIRLNV 1936
            +    + V
Sbjct: 2657 IKHYEVKV 2664



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV 3622
            +P ++ +  N++   EC    +  +S+   W+ +G+PL +   V    + G   L+I   
Sbjct: 2681 SPKEVKIKVNNTLTLECEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN-GHT-LQIKEA 2736

Query: 3623 YQRDAGLYTCKATNRHGE 3640
               D G YTC A+N  GE
Sbjct: 2737 QISDTGRYTCVASNIAGE 2754



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDL 1509
            PK ++  +    +  EC+   +  ++L   W+K+GQP+        I   G+  L I + 
Sbjct: 2682 PKEVKIKVNNT-LTLECEAYAIPSASLS--WYKDGQPLKSDDHVN-IAANGHT-LQIKEA 2736

Query: 1510 IAEDSGIYTCRAVNLVGTDEV 1530
               D+G YTC A N+ G DE+
Sbjct: 2737 QISDTGRYTCVASNIAGEDEL 2757



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/120 (30%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            EDS +Y  R  V   +  A    + L     +   +SA  EC     P P  R  W  +G
Sbjct: 2857 EDSLQYDVRVLVPPIIEGAN---SDLPEEVTVLVNKSALIECLSSGSPAP--RNSWQKDG 2911

Query: 1885 K-VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            + +L+  H    SN      L IL     D G Y C A N  G A     LNV    S+I
Sbjct: 2912 QPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2968



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 2964 PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNXQPIKLNTNTLIVP--GG 3018

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 3019 RTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLT 3052



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 2987 CEVSGFPPPDL--SWLKNXQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINXA 3042

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 3043 GESKKKFSLTVYVPPS-IKDHDSES 3066



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 3448 VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 3503

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 3504 KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 3538



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 3620 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 3675

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 3676 RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 3723



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 3923 GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 3980

Query: 724  AVLHV 728
              LHV
Sbjct: 3981 VTLHV 3985



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W +N + +    R+R T D    TL I +    DAG+Y C A N AG
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 8/74 (10%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  GNP P V W+ KK  L+  +  S +++    D SL +      + GEY CTA N  G
Sbjct: 1003 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPEGEESGEYVCTATNTAG 1058

Query: 154  EA----ICSVYIQP 163
             A      +VY++P
Sbjct: 1059 YAKRKVQLTVYVRP 1072



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            N + V   ++ LEC     G+ +  + W  +G P+K    FR   E     L+++S    
Sbjct: 1650 NKQVVIAHSLTLECNA--AGNPSPILTWLKDGVPVKANDNFR--IEAGGKKLEIMSAQEI 1705

Query: 1379 DSGVYTCQATNQLGE 1393
            D G Y C AT+  GE
Sbjct: 1706 DRGQYICVATSVAGE 1720



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 5/89 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP  + + Q+ + L+  +  +  CQ   +  P +   W  +G PLL K   +   +   +
Sbjct: 2103 PPNIMGEEQNVSVLIS-QAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENRSVL 2159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
             +    V  +D+G Y C ATN+ G  E K
Sbjct: 2160 KIEDAQV--QDTGRYTCEATNVAGKTEKK 2186



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 5/103 (4%)

Query: 3826 VSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   
Sbjct: 2961 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNXQ--PIKLNTNTLIVP 3016

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            G  +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 3017 GGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVYVPPSI 3059



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 3273 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 3332

Query: 724  AVLHVTPRATIERTSQHPETL 744
              L+V    TI       E L
Sbjct: 3333 FNLNVYVTPTIRGNKDEAEKL 3353



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 3275 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3334

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL T  D+ +
Sbjct: 3335 L------NVYVTPTI-RGNKDEAEKLMTYVDTSI 3361



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 3279 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3328



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T   T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 3355 TYVDTSINIECRX--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 3410

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 3411 VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 3453



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 3548 ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 3605

Query: 1791 LGE 1793
             G+
Sbjct: 3606 AGD 3608



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 3654 ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 3710



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 3713 PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 3769

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 3770 HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 3807



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 3829 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 3888

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 3889 TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 3937

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 3938 LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 3986



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 3897 PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 3953

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 3954 -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 3994



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 4261 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 4313

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 4314 LVIERVSKEDSGTYVCTAENSVG 4336



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 4377 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4433

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 4434 SLTLQSPPIITLE 4446



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  +T +   ++   G      C       P +   W  N   I   HRYR T D   
Sbjct: 609  QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDMFIVGSHRYRMTSD--- 663

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLK 2200
              L I     +D+G Y C A+N  G      TL+
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 792  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 1273 TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEEGTL-LVIASVT 1329

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 1330 PYDNGEYICVAVNEAGTTERKYNLKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILEEG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 1352

Query: 3510 MKV 3512
            +KV
Sbjct: 1353 LKV 1355



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNN-GKI-LKLFRATPEDAGRYSCKAINIAG 1438



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 1906



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 1671 SKKSI 1675
               S+
Sbjct: 1917 EPPSL 1921



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +     +DTG YT  A
Sbjct: 2029 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSTQISDTGRYTCVA 2085

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 2/48 (4%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ 992
            WLKDG P+     ++   N     L I+   V D G YTC A N  G+
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAGK 2182



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L  +T +EG  I      E  G P   + W K G  +   S        G   L +    
Sbjct: 2204 LTQLTVIEGNLISL--LCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE 2261

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
              D+  Y+C A +  G A+ +  L V  R TI  +  HP
Sbjct: 2262 KSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHP 2300



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG  + L  +      PNL   W K G  + T +  +     G   L I+     D+ 
Sbjct: 2209 VIEGNLISLLCESSGIPPPNLI--WKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2266

Query: 2714 IYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
            +Y+C A+N+ G A    ++++  R  +     HP  +
Sbjct: 2267 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2303



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W+++G P+  +  +  + D G++ L +K ++  D+G Y C A+N  G     
Sbjct: 2319 GIPPPTVTWMKDGHPLIKAKGVEIL-DEGHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2376

Query: 1798 STLFVQSKASL 1808
              L V +  S+
Sbjct: 2377 YDLSVHAPPSI 2387



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P   + W ++G P+E++  +  +   G   L +     +++G Y+C A NE GE +
Sbjct: 2604 PPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNAGRYSCVATNEAGEMI 2657



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 4/95 (4%)

Query: 2246 TELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQ 2305
            +E     +V EG +   EC+   V  P   I +Y NG+ +  +    I  D G + L I+
Sbjct: 3064 SESLSVVNVREGTSVSLECESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIK 3119

Query: 2306 HCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
                 D G+Y  +AIN  G       + V    SI
Sbjct: 3120 KAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSI 3154



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 3374 QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 3431

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 3432 FAPPNM----DNSMGTEEITVLKGSS 3453



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 3739 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 3792



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 3745 ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 3802

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 3803 VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 3853

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 3854 YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3886



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 4261 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 4313

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 4314 LVIERVSKEDSGTYVCTAENSVG 4336



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 8/79 (10%)

Query: 3840 TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899
            ++ + E +R  C+      PKL   W  N  ++P+   + +V   G   L I  V  EDS
Sbjct: 4271 SLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSELVIERVSKEDS 4324

Query: 3900 GEYICRAVNDFGEDFTKAT 3918
            G Y+C A N  G  F KAT
Sbjct: 4325 GTYVCTAENSVG--FVKAT 4341



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 945  WLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            W ++ R V  +  +RI T  N   ++L +KSV  +DAG Y C   +  G +  S  LT+ 
Sbjct: 553  WQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQ 609

Query: 1002 -VTKKDIIAESQHPGGLEKIQYLEDASRYSK 1031
               K  ++ ++Q   G  ++  +  A+ Y K
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPK 640



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    PK+ ++   G  V   C          K+ W  N   +   HR+R   D     
Sbjct: 612  PKVTVMPKN-QSFTGGSEVSIMCSATGYPKP--KIAWTVNDMFIVGSHRYRMTSDG---T 665

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L I +   +D+GIY C A N  GTD+ +  L
Sbjct: 666  LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            +T+T+   +   + +  + A    Q  + + V   P+  R   +++   G  V + C  Q
Sbjct: 1137 ITETRTSDSGMYLCVATNIAGNVTQAVK-LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G     + W   G  +        +     +++D  +  P D+G+YTC ATN  G   
Sbjct: 1196 --GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQAT--PSDAGIYTCVATNIAGTDE 1251

Query: 1396 TSCALRV 1402
            T   L V
Sbjct: 1252 TEITLHV 1258



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 5/120 (4%)

Query: 1824 LEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFN 1883
            + ++   +R+ +++V V    +   Q++  + L   Q  +  C +E  P P   + WY +
Sbjct: 1341 VNEAGTTERKYNLKVHVPPVIKDKEQVSNVSVLLN-QLTNLFCEVEGTPSPI--IMWYKD 1397

Query: 1884 GKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
               +      +T N+     L +     ED+G Y+CKAIN  G +     ++V    +II
Sbjct: 1398 NVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTII 1455



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1946 GNPVPVITWYKDNCLLS-GSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1998



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ID  V + P  +   +++ +V+  Q V   C+ + +    L   W K+G P+ +      
Sbjct: 2096 IDLRVYVPPNIMGEEQNV-SVLISQAVELLCQSDAIPPPTLT--WLKDGHPL-LKKPGLS 2151

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            I +   V L I D   +D+G YTC A N+ G  E
Sbjct: 2152 ISENRSV-LKIEDAQVQDTGRYTCEATNVAGKTE 2184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 8/144 (5%)

Query: 3962 DDLYDVDKKQPPRFVTQIQS--QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            D  YD+    PP  +   +S    S+VE  +    C+ +  G P     WF +G P+   
Sbjct: 2374 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS--GIPLPSTTWFKDGWPVSLS 2431

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
            N    +   G   +       ED+G+Y C   N  G +     +     P IV ++ L +
Sbjct: 2432 NSVRIL--SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL-E 2488

Query: 4080 HMKSIEKIREMEASWQVTPEQVVE 4103
             +K  EK + +  + +VT   V E
Sbjct: 2489 DVKVKEK-QSVTLTCEVTGNPVPE 2511



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3694 PPRFTVE-IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP    E   +++ V E   V   C V   G+P   I W  +G+P       H ++   F
Sbjct: 2478 PPHIVGENTLEDVKVKEKQSVTLTCEV--TGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2535

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I  +     G YTC A++  G
Sbjct: 2536 --LQITNVQVPHTGRYTCLASSPAG 2558



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  + E    P+  + W+K+G  L +   +    +    TL I   +  D+G YTC A+N
Sbjct: 2693 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASN 2750

Query: 2722 LLGE 2725
            + GE
Sbjct: 2751 IAGE 2754



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 2/72 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KDG+P+        F + G + L I +  + D G Y C A N  G A   
Sbjct: 2899 GSPAPRNSWQKDGQPLLEDDH-HKFLSNGRI-LQILNTQITDIGRYVCVAENTAGSAKKY 2956

Query: 997  ANLTIVTKKDII 1008
             NL +     +I
Sbjct: 2957 FNLNVHVPPSVI 2968



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN  GE+   
Sbjct: 2991 GFPPPDLSWLKNXQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKK 3048

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 3049 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3108

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 3109 ILADGQMLH 3117



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 3074 EGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 3129

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 3130 VCRAINVAG 3138



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 3358 DTSINIECRX--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 3413

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 3414 CVASNRAGVDNKHYNLQV 3431



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 3557 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3614

Query: 860  IRV 862
            +RV
Sbjct: 3615 VRV 3617



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 3729 KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 3783

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 3784 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 3821



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  +G+ ++   R + ++      L+I  V   DAG YTC A N  G ++ S KL V
Sbjct: 4111 ITWHKDGRAIVESIRQRVLSSGS---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4166



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 4365 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 4419

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 4420 CVATNEAG 4427



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPP   VP  +VT   G +      I    D    + W +N + +  +     I     +
Sbjct: 519 PPPVIQVP-NNVTVTPGERAVLTCLIISAVD--YNLTWQRNDRDVRLAEP-ARIRTLANL 574

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQ 739
           SL++ S+   D+GEY C   S  G +     L V   P+ T+   +Q
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 702  PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 757

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 758  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 799



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 1253

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQE 1277



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 10/123 (8%)

Query: 1834 EDVEVAVN-QAPRFITQLNGP--TKLSE---GQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887
            ++ E+ ++ Q P  +  L  P  T   E    Q   + C  +  P P   ++W  NG+ L
Sbjct: 1250 DETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT--IKWLHNGREL 1307

Query: 1888 QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
                   +  + G   L I +V   D+GEY C A+N  G       L V     +I+D +
Sbjct: 1308 TGREPGISILEEG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH-VPPVIKDKE 1365

Query: 1948 HES 1950
              S
Sbjct: 1366 QVS 1368



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 3/112 (2%)

Query: 1698 QRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN 1757
            Q++   D ++    + T   K++ V  N+    E ++   G P   + W ++G P+   +
Sbjct: 1441 QKYFNIDVLVPPTIIGTNFPKEVSVVLNRDVALECQV--KGTPFPDIHWFKDGKPLFLGD 1498

Query: 1758 RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQ 1809
                + D G V L++K     D G Y C   N  G+      L +    S++
Sbjct: 1499 PNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIK 1549



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 1838 VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 1894

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 1895 RYTCVATNAAGE 1906



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 1854 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 1912

Query: 2199 LKV 2201
            L V
Sbjct: 1913 LHV 1915



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++  LL SG    T  + G + +DI      
Sbjct: 1929 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNCLL-SGSTSMTFLNRGQI-IDIESAQIS 1984

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1985 DAGIYKCVAINSAG 1998



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 2001 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 2057

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 2058 GLQVLSGGRI-LALTSTQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 2109



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 2034 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSTQISDTGRYTCVAVN 2087

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 2088 AAGEKQRDIDLRV 2100



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G ++ LEC +Q +   T  V W  +G P+          E     L L +++  D
Sbjct: 2303 IIVTRGKSISLECEVQGIPPPT--VTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSD 2358

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
            +G Y C A N  G       L V A   +I   + P  +  ++
Sbjct: 2359 TGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVE 2401



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 2/54 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            P+  + WY +G+P++         + G+  L I  A   DTG Y C A+N  GE
Sbjct: 2703 PSASLSWYKDGQPLKSDDHVNIAAN-GHT-LQIKEAQISDTGRYTCVASNIAGE 2754



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVY 3623
            P ++ +  N SA  EC  +     + R  W  +G+PLL     K +++    IL+I    
Sbjct: 2880 PEEVTVLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGR--ILQILNTQ 2935

Query: 3624 QRDAGLYTCKATNRHGEATVSCKLQV 3649
              D G Y C A N  G A     L V
Sbjct: 2936 ITDIGRYVCVAENTAGSAKKYFNLNV 2961



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 3739 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 3791



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 4166 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 4223

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 4224 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4261



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 4377 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 4427


>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
           calmodulin and titin-interacting RhoGEF protein.
          Length = 6620

 Score =  124 bits (300), Expect = 6e-27
 Identities = 89/325 (27%), Positives = 141/325 (43%), Gaps = 14/325 (4%)

Query: 245 VGESDVQISTEIDRSLGPVSP-PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
           +GE+   +  ++D         P    +P + +++EG++A F+ ++ G+PRP V+W K+G
Sbjct: 88  IGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDG 147

Query: 304 QRLINSNKHEIITTH--NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP--- 358
           +RL   +   +        + LR+R  +  D G Y + AENP G    +  L V+S    
Sbjct: 148 RRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD 207

Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
           T S      +  +   Q+R    R E +  +      + C    VTEGK  R  C VTG 
Sbjct: 208 TASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCT---VTEGKHARLSCYVTGE 264

Query: 419 PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
           P PE  W  + + + +   H +  +   N  L I     SD G+ TC A N  G+T +  
Sbjct: 265 PKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT-YSS 323

Query: 479 RLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
            L V+ +  V    F +R   L VRE E        V  P+    W K+   +  + +  
Sbjct: 324 VLVVVREPAV---PFKKRLQDLEVREKESATFLCE-VPQPSTEAAWFKEETRLWASAKYG 379

Query: 539 IHTDGGASTLDIPRAKASDAAWYQC 563
           I  +G    L +    A D A Y C
Sbjct: 380 IEEEGTERRLTVRNVSADDDAVYIC 404



 Score =  122 bits (293), Expect = 4e-26
 Identities = 100/341 (29%), Positives = 149/341 (43%), Gaps = 44/341 (12%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLL 4572
            P F    QN  V  G  V  D  VTG     V W K+GK ++ D    I E+  G + L+
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK-DKPKPQTKAAN----------- 4620
            I    P D G Y C+A NS G +   AE  V L +T  D     T++++           
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245

Query: 4621 ------------APPEIIEPLKDKIVAEGQAI-EFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                          P+++E L+D  VA G  + +F  K+ G P P + W+K  + +  S 
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA---- 4723
            + +M+     +TL I     ED G Y     N+ G    +A+L V  PD+ +  PA    
Sbjct: 5306 HIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVH 5365

Query: 4724 --LTPLRDI------VVYEGQPAQFKTQITSKIKPTIQWLREGA------LIPETPDFQM 4769
              L P R +       V +G    F  ++  +  PT+ WLRE A      + P+TP + +
Sbjct: 5366 EQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV 5425

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                    L++ +   +  GT+TC A+ AAGQ   SA L V
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score =  103 bits (248), Expect = 1e-20
 Identities = 92/342 (26%), Positives = 141/342 (41%), Gaps = 30/342 (8%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--TL 323
            P    + +N ++Q+G    F   ++G P P V WFK+G +L+  + H +I         L
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDG-KLLEEDDHYMINEDQQGGHQL 5184

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY--VQD--QRSQYITDT---QQ 376
             +     +D G Y  LAEN  G   T   L V+  +  Y    D  + S Y +       
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244

Query: 377  RETEERIEISEKALAPQFVKVCQDRDVTEG-KMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            RE E     +++   PQ V+  +D  V  G ++ +F  +V G P P + WF  D Q    
Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF-KDGQPLTA 5303

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI------EK---- 485
              H  + ++   H L I +VT  DSG       N  G      RL V       EK    
Sbjct: 5304 SAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASD 5363

Query: 486  --EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPII--PNPEL 537
              EQ+V P+ +ERF+   V++G  +  + +  G P P + W ++    GV  I    P  
Sbjct: 5364 VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423

Query: 538  RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             + +     +L +          Y C A N AG     A L+
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLH 5465



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 103/424 (24%), Positives = 163/424 (38%), Gaps = 31/424 (7%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            S  P F  + +   V   + A    +  G P P + W ++  P+     F++        
Sbjct: 7    SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I  + + DS  +   A N  G A  +  L V+ +          P F L   ++ V  
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA---PHFLLRPTSIRVRE 123

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKV-QPDIRNKILEEDGTYTLL-ILEAYPQDSGKYE 4585
            G       +V G+    V W K+G+++ +PD     +EE G  + L I  A P+D G YE
Sbjct: 124  GSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYE 183

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQT----------------KAANAPPEIIEP- 4628
              A N  G A   A  VV   A     +P T                +A  AP       
Sbjct: 184  VRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTG 243

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-YTLRISEAFP 4687
             +   V EG+    SC + G+P P   W K  +L+   +   +   A E + L+I     
Sbjct: 244  TRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ 303

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
             D G Y C A N  G+   +  + V +P     +P    L+D+ V E + A F  ++   
Sbjct: 304  SDRGLYTCTASNLVGQTYSSVLVVVREP----AVPFKKRLQDLEVREKESATFLCEVPQP 359

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
                  W +E   +  +  + +  EG    L + N   +D   + C   T  G   T A+
Sbjct: 360  -STEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE--TPEGS-RTVAE 415

Query: 4808 LVVK 4811
            L V+
Sbjct: 416  LAVQ 419



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 87/334 (26%), Positives = 132/334 (39%), Gaps = 30/334 (8%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP+F+   +   V+ GK     C++ G P P+V+W  + + +      + L  +   + L
Sbjct: 9   APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFR-LAQDGDLYRL 67

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVERFSTLNVREGEPV 508
            I ++ L DSG   C ARN  GE      L V  +      AP F+ R +++ VREG   
Sbjct: 68  TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEA 127

Query: 509 VLNARAVGTPTPRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
               R  G+P P ++W KDG  +     P +R+   G AS L I  A+  D   Y+  A+
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187

Query: 567 NVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIP 626
           N  G+ +  A L                  RP                L H++R R  + 
Sbjct: 188 NPLGAASAAAALVVDSDAADTAS-------RP---------GTSTAALLAHLQRRREAM- 230

Query: 627 PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686
              E     PP      ++ T  EG   H        G+P  +  W K+GQ +    R  
Sbjct: 231 -RAEGAPASPPS--TGTRTCTVTEGK--HARLSCYVTGEPKPETVWKKDGQLVTEGRRHV 285

Query: 687 SIFRFGY--ISLDMLSLNIQDSGEYTCRAVSATG 718
            ++        L +L     D G YTC A +  G
Sbjct: 286 -VYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 8/194 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP+  E L D     G+ ++ +C++ G P P + WYK  K ++   +  +    D     
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 4682 ISEAFPE-DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I ++    D G Y C A ++AG  +   K+ V  P +  N    +P       EG+ AQF
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPF-----VEGEDAQF 6127

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRATTA 4798
               I     P I+W ++GAL+     FQ + E  +   VL+I    +ED G + C     
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187

Query: 4799 AGQVETSAKLVVKS 4812
             G    SA+L ++S
Sbjct: 6188 LGSARASAELRIQS 6201



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 57/208 (27%), Positives = 103/208 (49%), Gaps = 8/208 (3%)

Query: 4514 PSFTLTAQNVNVTSG-QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            P      +++ V  G +L +   KV G     +YW K+G+ +      ++ ++   +TL 
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLP-ATKDKPKPQTKAANAPPEIIEPLKD 4631
            I+    +DSG+Y     N+ G A   A  +V  P   ++KP         PP ++E    
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTP 5379

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWY-----KGDKLIKP-SKYFQMSRTADEYTLRISEA 4685
            K V +G +I FS K+ G+P+PTV W      +G   I P +  + ++ +A +++L + + 
Sbjct: 5380 KKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDV 5439

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
              + +G Y C+A N+AG+   +A L V+
Sbjct: 5440 GRQHQGTYTCIASNAAGQALCSASLHVS 5467



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIRNKILEE-DGTYT 4570
            PP F     +     G+ V+L  +VTGT KP+ + W K+GK VQ D  + ++E+ DG+  
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPV-ISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L++      DSG+Y C A ++AG      + +V +P                P  +  ++
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP----------------PRFVNKVR 6115

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--MSRTADEYTLRISEAFPE 4688
                 EG+  +F+C I G P P ++WYK   L+     FQ      +    L I  A  E
Sbjct: 6116 ASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKE 6175

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            D G Y+C   N  G    +A+L++  P
Sbjct: 6176 DLGLYECELVNRLGSARASAELRIQSP 6202



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/230 (29%), Positives = 107/230 (46%), Gaps = 9/230 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT-SIFRFGYIS 695
            P F+  L++    +G  + F+  +   G P   + W K+G+ +E    +  +  + G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT-IERTSQHPETLQYIQQLEDYS 754
            L + ++   D G Y C A ++ GV+ TKA L V   +T  +  +   E+  Y    + Y 
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA-QGYL 5242

Query: 755  KYQHQESIEEQTS--QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
              + QE  E  T   Q PQ +  L+DL      R A F  QL     P  R+ W+KDG+P
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKF--QLKVKGYPAPRLYWFKDGQP 5300

Query: 813  ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +TAS+ I         +L I+ +  ED+G Y     N +G A S+A + V
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 60/202 (29%), Positives = 92/202 (45%), Gaps = 5/202 (2%)

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
            Q + + AP  +  P K  +V+ G+    SC+IVG P P V W K  + +     F++++ 
Sbjct: 3    QPQFSGAPRFLTRP-KAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNLP-ALTPLRDIVV 4732
             D Y L I +    D G Y C A N+ G    A  L+V  +   A+  P  L     I V
Sbjct: 62   GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRV 121

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALI--PETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             EG  A F+ ++    +P + W ++G  +  P+ P  ++   G  + L I      D GT
Sbjct: 122  REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181

Query: 4791 FTCRATTAAGQVETSAKLVVKS 4812
            +  RA    G    +A LVV S
Sbjct: 182  YEVRAENPLGAASAAAALVVDS 203



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 92/364 (25%), Positives = 153/364 (42%), Gaps = 26/364 (7%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYV 1768
            APVF   +++  V +     F+   +  G P   V W ++G  +E  +      D  G  
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQ--LESQHESALQKIQQLED 1826
             L +  V P D G Y C A N +G + T + L V   ++         ES+     Q   
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
            SSR Q   +      Q P+ + +L         + A ++ +++ YP P  R+ W+ +G+ 
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYWFKDGQP 5300

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946
            L +    R ++      L+I++V  EDSG+Y     N +G A SS RL V+  +    + 
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD----EP 5356

Query: 1947 QHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND 2006
            + + A +  + L      +R      F  +K + G  I  +   EG PV     L    +
Sbjct: 5357 EEKPASDVHEQLVPPRMLER------FTPKKVKKGSSITFSVKVEGRPVPTVHWLR--EE 5408

Query: 2007 PTMRVEWYCNGRPVQQGHRF-KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
                V W     P   G+    +      V LD+     +  GTY C A+NA G+A+ ++
Sbjct: 5409 AERGVLWI---GPDTPGYTVASSAQQHSLVLLDV---GRQHQGTYTCIASNAAGQALCSA 5462

Query: 2066 SVKV 2069
            S+ V
Sbjct: 5463 SLHV 5466



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F +   D     G+  +  CRVTG P P ++W+ + + ++ D +H ++ +  G+ AL+
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            + ++T  DSG   C A + +G  +   ++ V      V P+FV +       EGE     
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFT 6128

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVA 569
                G P P+I W KDG  +    + +  ++   G   L I  A   D   Y+C   N  
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188

Query: 570  GSTATRARL 578
            GS    A L
Sbjct: 6189 GSARASAEL 6197



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 61/258 (23%), Positives = 111/258 (43%), Gaps = 22/258 (8%)

Query: 266  PKIAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P++ ++ R+ ++  G   A+FQ+++ G P PR+ WFK+GQ L  S    +       TL 
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            + +  + DSG Y     N  G   +S  L V  P E                 E +   +
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEP----------------EEKPASD 5363

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-----IRDDYNHK 439
            + E+ + P+ ++    + V +G    F  +V GRP P V W   + +     I  D    
Sbjct: 5364 VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423

Query: 440  ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
             + + +  H+L++ +V     G  TC+A N +G+      L+V    +V   + V+    
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 5483

Query: 500  LNVREGEPVVLNARAVGT 517
                +G    ++A+ + T
Sbjct: 5484 STFLQGTTQAISAQGLET 5501



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 90/406 (22%), Positives = 162/406 (39%), Gaps = 48/406 (11%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T  +Q     E   A F  E   E    ++W     P+ N    +I     +  L+++ +
Sbjct: 2561 TGPLQDAEATEEGWASFSCELSHEDEE-VEWSLNGMPLYNDSFHEISHKGRRHTLVLKSI 2619

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
               D+ +       R  + K S +  +E +       + P  F     +++      + L
Sbjct: 2620 QRADAGIV------RASSLKVSTSARLEVR-------VKPVVFLKALDDLSAEERGTLAL 2666

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              +V+  +   V W K+G ++ P  +   L   GT  L++ +  P+D+G Y C   +   
Sbjct: 2667 QCEVSDPEA-HVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEET 2725

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR                    +  +    I + LK   V EG++  F C +  +    
Sbjct: 2726 RAR-------------------VRVHDLHVGITKRLKTMEVLEGESCSFECVLSHESASD 2766

Query: 4654 -VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
               W  G K +  S  FQ +R   +Y L + EA P D G+   V ++  G +T  A L V
Sbjct: 2767 PAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGE---VVFSVRG-LTSKASLIV 2822

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
             +   A     + PL D  V  G+  + + +++    P + WL++   I ++  + ++ E
Sbjct: 2823 RERPAA----IIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCE 2877

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRA----TTAAGQVETSAKLVVKSKT 4814
            G  A+L+I     +D G +TC      +TA+  VE  A    +  T
Sbjct: 2878 GTMAMLVIRGASLKDAGEYTCEVEASKSTASLHVEEKANCFTEELT 2923



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 9/231 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYVA 2036
            P F   ++N EV +G+PV  +  +T    P   V W+ +G+ +++   +    D  G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096
            L I      D G Y C A N++G + T + ++VD  S  Y    D          + Y  
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243

Query: 2097 PKPIEEEQP----GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
             +  E  +     GQ P  +  L  L+       A F+ +V+    P L   WF +GQ +
Sbjct: 5244 SREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLY--WFKDGQPL 5301

Query: 2153 RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
             A    R T       L+I+    EDSG Y    +N +G A ++  L V G
Sbjct: 5302 TASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 100/393 (25%), Positives = 157/393 (39%), Gaps = 53/393 (13%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSILIIRQVFVEDSAV 4480
            V E   A F           + W+ +  P+  +   +I        +L +RQ+ ++DS  
Sbjct: 3016 VQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGT 3075

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
                A    G  + SA L V EK         P  F+    +  +T G+ + L  + T T
Sbjct: 3076 IYFEA----GDQRASAALRVTEK---------PSVFSRELTDATITEGEDLTLVCE-TST 3121

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
              I V W K+GK ++   R ++  E     LLI  A  QDSG+Y+C     AG A C + 
Sbjct: 3122 CDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC----EAGGA-CSSS 3176

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             V              +    P    E LKD  V EG A    C +     P V+W  G+
Sbjct: 3177 IV--------------RVHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGN 3221

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
             +++P   + + +      L +    P+D G Y C    S G  T +A L VT       
Sbjct: 3222 NVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTA------ 3271

Query: 4721 LPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778
            LPA  +  LR+    EG  A  + ++ SK  P ++W +    + +   + +  +G    L
Sbjct: 3272 LPAQFIGKLRNKEATEGATATLRCEL-SKAAP-VEWRKGSETLRDGDRYCLRQDGAMCEL 3329

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             I      D   ++C      G+  TSA L ++
Sbjct: 3330 QIRGLAMVDAAEYSC----VCGEERTSASLTIR 3358



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 106/440 (24%), Positives = 180/440 (40%), Gaps = 56/440 (12%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            I R++ + +  EI+  A+  E   +  VK   P    + ++     E  +   E +    
Sbjct: 2258 IYRRVLAEDAGEIQFVAENAESRAQLRVK-ELPVTLVRPLRDKIAMEKHRGVLECQVSRA 2316

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
                ++W++ +  ++  P +++ +      LII  V  ED   +   A    G  K SA 
Sbjct: 2317 SAQ-VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQ 2371

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVT--SGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              VEE+      G+         Q+V V   +      +T +   +P    WL  GK V 
Sbjct: 2372 FFVEEQSITIVRGL---------QDVTVMEPAPAWFECETSIPSVRPPK--WLL-GKTVL 2419

Query: 4556 PDIRNKILEEDGT-YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                N  LE++GT + L++       +G        + G++R  A  VVS          
Sbjct: 2420 QAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHF----TVGKSRSSARLVVS---------- 2465

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSR 4673
                 + P  +  PL+ K   E Q++  SC    +P P  VQWYK D  + PS+ F+MS 
Sbjct: 2466 -----DIPVVLTRPLEPKTGRELQSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSL 2518

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  LRI    P D G Y+C     AG    + ++ V    +A  +    PL+D    
Sbjct: 2519 EGQMAELRILRLMPADAGVYRC----QAGSAHSSTEVTV----EAREVTVTGPLQDAEAT 2570

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            E   A F  +++ +    ++W   G  +      ++ H+G    L++ +    D G    
Sbjct: 2571 EEGWASFSCELSHE-DEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG--IV 2627

Query: 4794 RATTAAGQVETSAKLVVKSK 4813
            RA++   +V TSA+L V+ K
Sbjct: 2628 RASSL--KVSTSARLEVRVK 2645



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 69/232 (29%), Positives = 99/232 (42%), Gaps = 13/232 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI-EASNRLTTMHDFGY 1767
            QAP F +    IRV E   A F  R+   G P+  V W ++G  + E       + + G 
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRV--GGSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165

Query: 1768 V-ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLED 1826
              AL ++   P D GTY  RA N LG A  ++ L V S A+        S    +  L+ 
Sbjct: 166  ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ- 224

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                +RRE +      A    T     T ++EG+ A   C +   P P     W  +G++
Sbjct: 225  ----RRREAMRAEGAPASPPSTGTRTCT-VTEGKHARLSCYVTGEPKP--ETVWKKDGQL 277

Query: 1887 LQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            +  G R+    D      L IL     D G YTC A N +GQ  SS+ + V+
Sbjct: 278  VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 92/386 (23%), Positives = 153/386 (39%), Gaps = 38/386 (9%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-TETNNFGFV 1635
            AP+  T L+N E+++G    F+   +        V W+ + K L+    +    +  G  
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFD--CVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY----LESQHEGALPRLNQL 1691
             L I + +P D G Y C A N++G + T     V    + Y      ++          L
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAE-NQAAHFEARLIPVGDPKLRVEWLRNG 1750
                +    S  DE   Q P     ++D++VA   + A F+ ++   G P  R+ W ++G
Sbjct: 5243 SSREQEGTESTTDE--GQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKDG 5298

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             P+ AS  +          L +  V  EDSG Y     N +G A +S+ L V+       
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD---- 5354

Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870
            E + + A    +QL                   PR + +   P K+ +G S  +  ++E 
Sbjct: 5355 EPEEKPASDVHEQL-----------------VPPRMLERFT-PKKVKKGSSITFSVKVEG 5396

Query: 1871 YPDPNMR-VEWYFNGKVLQSG---HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             P P +  +       VL  G     Y  ++     +L +L V  +  G YTC A N  G
Sbjct: 5397 RPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG 5456

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESAL 1952
            QA+ S  L+V     +    + + AL
Sbjct: 5457 QALCSASLHVSGLPKVEEQEKVKEAL 5482



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 84/325 (25%), Positives = 133/325 (40%), Gaps = 22/325 (6%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F T  K  V +S G+ A     ++  G+ +  + W  + + + A  R R      +  
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQIV--GNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKG---QKPRFTTHIQNIEGLKDG 3164
            L IL     DSG Y CRA N  G+A  +V L+ VD       Q P F     +I  +++G
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQ-VDAEAACAEQAPHFLLRPTSIR-VREG 124

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRH--STRIKTVSDFGFV-VLDIAYTQNHDSGE 3221
              A F C V     P   + W  +G+ +      R++ V + G    L I   +  D G 
Sbjct: 125  SEATFRCRV--GGSPRPAVSWSKDGRRLGEPDGPRVR-VEELGEASALRIRAARPRDGGT 181

Query: 3222 YVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            Y  RA N  G     A +                + A +  L+  + A  +    P A P
Sbjct: 182  YEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA-MRAEGAP-ASP 239

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIV 3340
            P   T+   VT   EG+ A     +    +P  +  W  +G+ +  G R+  + D     
Sbjct: 240  PSTGTRTCTVT---EGKHARLSCYV--TGEPKPETVWKKDGQLVTEGRRHVVYEDAQENF 294

Query: 3341 ILDILYCYEENSGEYECVATNKLGR 3365
            +L IL+C + + G Y C A+N +G+
Sbjct: 295  VLKILFCKQSDRGLYTCTASNLVGQ 319



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 63/233 (27%), Positives = 101/233 (43%), Gaps = 7/233 (3%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S + PVF+  L N   V +G  +  +C +   G P   V WF +G+ +     +    D 
Sbjct: 5122 SDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQL 1290
             G   L I     AD G Y   A N +G + T A +RV +  +D  T     ++      
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238

Query: 1291 LEDAARRTKQVREDITVM-QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN 1349
                + R ++  E  T   Q PQ    L +++   GT +  + +L+  G    R+ WF +
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFKD 5297

Query: 1350 GKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            G+P+      R   +     L+++SV  EDSG Y    +N +G A +S  L V
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 34/92 (36%), Positives = 54/92 (58%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F+   Q+++V +G    FDC VTG+P P V WF + + + +D ++ I  ++ G H L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            +IT V  +D GV  C+A N  G ++ +  L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 65/220 (29%), Positives = 94/220 (42%), Gaps = 15/220 (6%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT--GSRVHTLNDFGFIALDIDYIY 3761
            +I V EG    F CRV   G P   + W  +GR      G RV         AL I    
Sbjct: 118  SIRVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAAR 175

Query: 3762 ARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPK 3821
             RD G Y  RA N  G+A+  A +   +  D    +  P   +   +  L+R R  +A +
Sbjct: 176  PRDGGTYEVRAENPLGAASAAAALVVDS--DAADTASRPGTSTAALLAHLQRRR--EAMR 231

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
             E   ++PP   T  ++ TV E +  R  C V    +PK    W ++G+L+  G R+   
Sbjct: 232  AEGAPASPPS--TGTRTCTVTEGKHARLSCYVTG--EPKPETVWKKDGQLVTEGRRHVVY 287

Query: 3882 YDM--GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             D    FV L IL+    D G Y C A N  G+ ++   +
Sbjct: 288  EDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 57/200 (28%), Positives = 88/200 (44%), Gaps = 14/200 (7%)

Query: 4428 ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAEN 4487
            A+F+++  G P P + W+++  P+  S   ++        L I  V  EDS  +AA   N
Sbjct: 5278 AKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISN 5337

Query: 4488 RGGTAKCSANLVV------EEKRRQG-RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
              G A  SA L+V      EEK        +VPP          V  G  +    KV G 
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR 5397

Query: 4541 KPIDVYWLKNGKK-----VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
                V+WL+   +     + PD     +      ++L++L+   Q  G Y C+A N+AG+
Sbjct: 5398 PVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457

Query: 4595 ARCDAECVVS-LPATKDKPK 4613
            A C A   VS LP  +++ K
Sbjct: 5458 ALCSASLHVSGLPKVEEQEK 5477



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 79/288 (27%), Positives = 115/288 (39%), Gaps = 19/288 (6%)

Query: 1835 DVEVA-VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL--QSGH 1891
            D E A   QAP F+ +     ++ EG  A + CR+   P P   V W  +G+ L    G 
Sbjct: 100  DAEAACAEQAPHFLLRPTS-IRVREGSEATFRCRVGGSPRP--AVSWSKDGRRLGEPDGP 156

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
            R R       +AL I      D G Y  +A N LG A ++  L V S  +        S 
Sbjct: 157  RVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTST 216

Query: 1952 LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
               + +L+   R + A++ +      P  G   +   VTEG    L   +T   +P    
Sbjct: 217  AALLAHLQ---RRREAMRAEGAPASPPSTGT--RTCTVTEGKHARLSCYVT--GEPKPET 269

Query: 2012 EWYCNGRPVQQGHRFKTTYDFGY-VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             W  +G+ V +G R     D      L IL+    D G Y C A+N VG+  T SSV V 
Sbjct: 270  VWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ--TYSSVLVV 327

Query: 2071 AKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSL 2118
             +         ++RL+ ++  EK       E  QP     +    T L
Sbjct: 328  VREPA---VPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRL 372



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 32/108 (29%), Positives = 60/108 (55%), Gaps = 1/108 (0%)

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
            P    +P P    ++A P  +  L+++ V +G  + F C + G+P+P+V+W+K  KL++ 
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEE 5168

Query: 4666 SKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
              ++ ++      + L I+   P D G Y+C+A NS G  +  A+L+V
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 7/239 (2%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SL 2833
            VF++ L N   ++G  + F+C V  +  P   + WF + K L     Y    D      L
Sbjct: 5127 VFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             IT     D G+Y C A NS G ++T   LR       Y         +   + +    +
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
            R  +G   +  + + P+   ++    + Q+  G  L  + Q++ K  P  ++ W+ +G+ 
Sbjct: 5245 REQEGTESTTDEGQLPQ---VVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFKDGQP 5300

Query: 2954 LEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
            L   +  ++T      TL+++ V   DSG Y     N  G A++S+ +     D   E+
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEK 5359



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 95/421 (22%), Positives = 163/421 (38%), Gaps = 45/421 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +F KK++P  V E      EVE    P P ++W R    +    + +IH    +  L+
Sbjct: 1987 PVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  V   D   F     +     K  A L VE ++ +   G+   +     Q       Q
Sbjct: 2046 LHNVGFADRGFFGCETPDD----KTQAKLTVEMRQVRLVRGL--QAVEAREQGTATMEVQ 2099

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
            L   D        +D  W ++G + Q      +      +TL +    P+DSG     A 
Sbjct: 2100 LSHAD--------VDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAE 2151

Query: 4590 NSAGEARCDA-ECVVSLP------ATKDKPKPQTKAANAPPEI-IEPLKDKI-VAEGQAI 4640
                 AR    E  VS         T +K K   +   + P + +  LKD + +  G+ +
Sbjct: 2152 GVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTM 2211

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD------EYTLRISEAFPEDEGDYK 4694
              + +   + L   +    D+ +          +A        YTL       ED G+ +
Sbjct: 2212 AIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQ 2271

Query: 4695 CVAYNSAGRVTVAAK-LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
             VA N+  R  +  K L VT          + PLRD +  E      + Q+ S+    ++
Sbjct: 2272 FVAENAESRAQLRVKELPVT---------LVRPLRDKIAMEKHRGVLECQV-SRASAQVR 2321

Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            W +    +   P ++++ +G    L+I + + ED  T+TC     AG V+TSA+  V+ +
Sbjct: 2322 WFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTC----DAGDVKTSAQFFVEEQ 2377

Query: 4814 T 4814
            +
Sbjct: 2378 S 2378



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 84/370 (22%), Positives = 146/370 (39%), Gaps = 47/370 (12%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W + +  ++    + +    T+  L I  + V D+  ++ V     G  + SA L V 
Sbjct: 3831 VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVR 3886

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
              +         P F    Q++    G    L  +++      V W K G ++Q + R +
Sbjct: 3887 APQ---------PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKGGLQLQANGRRE 3936

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
               +  T  L++ +   +D+G+Y C   + A  A        +L  T            A
Sbjct: 3937 PRLQGCTAELVLQDLQREDTGEYTCTCGSQATSA--------TLTVTA-----------A 3977

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   +  L+ + V EG      C++  +   +V+W KG   + P   +QM +      L 
Sbjct: 3978 PVRFLRELQHQEVDEGGTAHLCCEL-SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELL 4036

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            +     ED GDY C      G     A L V  P         T L+ +    G  A+  
Sbjct: 4037 VRGVEQEDAGDYTC----DTGHTQSMASLSVRVPRPKFK----TRLQSLEQETGDIARLC 4088

Query: 4742 TQIT-SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             Q++ ++    +QWL+EG  +   P ++M  +G    LLI     +DTG + C      G
Sbjct: 4089 CQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC----VTG 4144

Query: 4801 QVETSAKLVV 4810
              +T+A L V
Sbjct: 4145 GQKTAASLRV 4154



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 99/448 (22%), Positives = 173/448 (38%), Gaps = 45/448 (10%)

Query: 4349 DPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPS 4408
            DP+  TV GK V  + + Q  ++      + R+   ++  E+    +         V+  
Sbjct: 2766 DPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVR-E 2824

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P    K ++   V   E      E      P + W ++   I+ S  + +    T ++L
Sbjct: 2825 RPAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAML 2883

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +IR   ++D+  +    E     +K +A+L VEEK            FT    N+ V   
Sbjct: 2884 VIRGASLKDAGEYTCEVE----ASKSTASLHVEEKAN---------CFTEELTNLQVEEK 2930

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                   K T      V W K   +++   +++  +E  T  L I      DS  Y C  
Sbjct: 2931 GTAVFTCK-TEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTC-- 2987

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
                G+A+  A+ +V           Q +  +    IIE L+D  V EG +  F C+I  
Sbjct: 2988 --DIGQAQSRAQLLV-----------QGRRVH----IIEDLEDVDVQEGSSATFRCRISP 3030

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                 V W+     +  ++  ++      Y  L + +   +D G      Y  AG    +
Sbjct: 3031 ANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG----TIYFEAGDQRAS 3086

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            A L+VT+     +      L D  + EG+      + TS     + W ++G  +  +   
Sbjct: 3087 AALRVTEKPSVFS----RELTDATITEGEDLTLVCE-TSTCDIPVCWTKDGKTLRGSARC 3141

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            Q+ HEG+ A LLI     +D+G + C A
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEA 3169



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 81/369 (21%), Positives = 144/369 (39%), Gaps = 49/369 (13%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W++ +  +++     +     +  L IR +  ED+  +  +     G  + SA L V 
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVR 3710

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
                      +P  F    +N   T G    L  +++   P++  W K  + ++   R+ 
Sbjct: 3711 A---------MPSKFIEGLRNEEATEGDTATLWCELSKAAPVE--WRKGHETLRDGDRHS 3759

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            + ++     L I      D+G+Y CV     G+ R  A   V                  
Sbjct: 3760 LRQDGSRCELQIRGLAVVDAGEYSCVC----GQERTSATLTVRA---------------L 3800

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   IE +K++   EG      C++  K  P V+W KG + ++    + + +      L+
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQ 3858

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I      D G+Y CV     G+   +A L V  P          PL+ +   EG  A  +
Sbjct: 3859 IHGLSVADTGEYSCV----CGQERTSATLTVRAPQPVFR----EPLQSLQAEEGSTATLQ 3910

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             ++ S+   T+ W + G  +      +   +G  A L++ +   EDTG +TC      G 
Sbjct: 3911 CEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC----TCGS 3965

Query: 4802 VETSAKLVV 4810
              TSA L V
Sbjct: 3966 QATSATLTV 3974



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 47/198 (23%), Positives = 82/198 (41%), Gaps = 9/198 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + + R ++  +      ++  +D DV EG    F CR++   Y  V WF++   +  +  
Sbjct: 2991 QAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANEL 3050

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
            ++I     G H L +  + L DSG +      ++G+      L V EK  V    F    
Sbjct: 3051 NEIDAQPGGYHVLTLRQLALKDSGTIYF----EAGDQRASAALRVTEKPSV----FSREL 3102

Query: 498  STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            +   + EGE + L         P + W KDG  +  +   ++  +G  + L I  A   D
Sbjct: 3103 TDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQD 3161

Query: 558  AAWYQCTAQNVAGSTATR 575
            +  Y+C A     S+  R
Sbjct: 3162 SGRYKCEAGGACSSSIVR 3179



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 117/538 (21%), Positives = 213/538 (39%), Gaps = 53/538 (9%)

Query: 4280 KLQELENEQVIKESRLRESTHQYAIP-GDKVTSNTVAKSMAQ-RYEDNLDQTEEVTEQRV 4337
            +LQ    E V+++ + RE T +Y    G + TS T+  + A  R+   L Q +EV E   
Sbjct: 3938 RLQGCTAELVLQDLQ-REDTGEYTCTCGSQATSATLTVTAAPVRFLREL-QHQEVDEGGT 3995

Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQ 4397
                 +  R     E      ++    + Q  ++    + + R +   +  +        
Sbjct: 3996 AHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHT 4055

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEF-DGEPLPLIKWYRENFPIKNSPD 4456
            + +    V+  +P  F  ++Q       + AR   +  D E   +++W +E   +   P 
Sbjct: 4056 QSMASLSVRVPRPK-FKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPK 4114

Query: 4457 FQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
            +++ +      L+I Q+  +D+  +A V     G  K +A+L V E       G+V    
Sbjct: 4115 YEMRSQGATRELLIHQLEAKDTGEYACVT----GGQKTAASLRVTEPEVTIVRGLV---- 4166

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLILE 4575
                 +  VT+ + V    +V+      V W   G  +Q +   ++   DG  +TL +  
Sbjct: 4167 -----DAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKG 4221

Query: 4576 AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA 4635
              P+D+G       N A  A    +  V  P                  I+EPL+D  ++
Sbjct: 4222 VTPEDAGTVSFHLGNHASSA----QLTVRAPEVT---------------ILEPLQDVQLS 4262

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            EGQ   F C++        +W  G   ++ ++   +  T ++ TL +         D   
Sbjct: 4263 EGQDASFQCRLSRASGQEARWALGGVPLQANEMNDI--TVEQGTLHLLTLHKVTLEDAGT 4320

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            V+++  G  +  A+LKVT    A N   +  L ++   EG  A F+ Q++        WL
Sbjct: 4321 VSFH-VGTCSSEAQLKVT----AKN-TVVRGLENVEALEGGEALFECQLSQPEVAAHTWL 4374

Query: 4756 REGALI--PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +   +   E  +      G   +LL+ N   +D    +CR T  AG + TSA L V+
Sbjct: 4375 LDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQD----SCRVTFLAGDMVTSAFLTVR 4428



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 103/439 (23%), Positives = 178/439 (40%), Gaps = 54/439 (12%)

Query: 2043 YAEDTGTYMCKATNAVGEA--VTTSSVKVDAKSGLYLDT-LDEQRLKKIQELEKYERPKP 2099
            Y ED   ++C    A+ EA    T   ++ A  G+ ++  L EQ  ++++     E P P
Sbjct: 5051 YREDEH-FICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPAP 5109

Query: 2100 IEEEQP-------GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
            +   +P          PVFLT L + E +++G    F+C V     P  ++ WF +G+ +
Sbjct: 5110 VVPPEPLPSLLTSDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLL 5166

Query: 2153 RAGHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
                 Y    D  G   L I      D G Y C A N +G +     L+V    +   DT
Sbjct: 5167 EEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV-DLTSTDYDT 5225

Query: 2212 QHPNGLEKIRQLEAQGHSTRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQV 2266
               +  E      AQG+ +  E E  + +      P+ V ELR        + A F+ +V
Sbjct: 5226 A-ADATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV 5284

Query: 2267 EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHC 2326
            +    P  R+ ++ +G+ L ++A   +T      +L+I     ED+G+Y+    NA+G  
Sbjct: 5285 KGYPAP--RLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342

Query: 2327 TSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNID 2386
             S+  + V              G ++  E  +++  ++   P  + R  P          
Sbjct: 5343 YSSARLLV-------------RGPDEPEEKPASDVHEQLVPPRMLERFTP---------K 5380

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK------LIEDSSRITKTHDFGYVSMTISH 2440
             +++G +  F  ++   G P   V W R E       +  D+   T        S+ +  
Sbjct: 5381 KVKKGSSITFSVKV--EGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLD 5438

Query: 2441 VRDEDEGVYMCRASNLLGE 2459
            V  + +G Y C ASN  G+
Sbjct: 5439 VGRQHQGTYTCIASNAAGQ 5457



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 86/408 (21%), Positives = 164/408 (40%), Gaps = 42/408 (10%)

Query: 4390 IEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449
            IE   + + R   G +  +KPP    +    R+  HE+A+   E   +    + W ++  
Sbjct: 689  IESSIRMEVRAAPG-LTANKPPAAAAREVLARL--HEEAQLLAELSDQAAA-VTWLKDGR 744

Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
             +   P +++   + + +L++R V  +D+ ++  V+  RGG  + +  L V     QG  
Sbjct: 745  TLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVS--RGG--RIAYQLSV-----QGLA 795

Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT- 4568
              +     +    V+  +G   + + + T    + V+W K+G ++       + E+ GT 
Sbjct: 796  RFLHKD--MAGSCVDAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTR 852

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            + L+      QD G Y C      GE   D    VS P          K   A  ++   
Sbjct: 853  HRLVAATVTRQDEGTYSC----RVGEDSVDFRLRVSEP----------KVVFAKEQLA-- 896

Query: 4629 LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
             + K+ AE G +   SC+ V +    V WYK  K +  S    M  T     L + +A  
Sbjct: 897  -RRKLQAEAGASATLSCE-VAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQ 954

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
             D G+Y C     AG   ++  L V +P        +    ++    G  A    ++ ++
Sbjct: 955  ADAGEYSC----EAGGQRLSFHLDVKEPKVVFAKDQVAH-SEVQAEAGASATLSCEV-AQ 1008

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
             +  + W ++G  +  +    +  +G    L++    + D G ++C A
Sbjct: 1009 AQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 115/497 (23%), Positives = 193/497 (38%), Gaps = 63/497 (12%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+++   C +  +  P   + W  + K +    +Y    + +   L I     +D+G YT
Sbjct: 2841 GEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897

Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTE 2907
            C+   SK +A    SL      N + +         L+  E+       K   P+   T 
Sbjct: 2898 CEVEASKSTA----SLHVEEKANCFTEEL-----TNLQVEEKGTAVFTCKTEHPAATVT- 2947

Query: 2908 YPKPEWIIPIAAEHQ-LVEGQVLHLEGQVEPKNDPDLKI----EWYFNGKVLEQGSRFKL 2962
            + K    +  + +HQ   EG  L L      K D D       +     ++L QG R  +
Sbjct: 2948 WRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHI 3007

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA---FTSSTVYCTSKDNLIERTQHPKGT 3019
              D     L+ VDV E  S  + C+      E    F   T    ++ N I+    P G 
Sbjct: 3008 IED-----LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDA--QPGGY 3060

Query: 3020 EGLEKIQ-NLEDS--LRKEPGQQPDDDTGRPPEFTTVF-KDIVD--ISEGQIAHYEASLI 3073
              L   Q  L+DS  +  E G Q      R  E  +VF +++ D  I+EG+    + +L+
Sbjct: 3061 HVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE----DLTLV 3116

Query: 3074 -PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
              T    + + W  +GKT+  S R +  +      L I G    DSG Y C A      +
Sbjct: 3117 CETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSS 3176

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
             + V    V        RF   ++++E L +G +A   C +  V  P   ++W +    +
Sbjct: 3177 IVRVHARPV--------RFQEALKDLEVL-EGGAATLRCVLSSVAAP---VKWCYGNNVL 3224

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESL 3252
            R   +     +   + L +   +  DSG Y C     +G+  T AT+         + +L
Sbjct: 3225 RPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLT--------VTAL 3272

Query: 3253 QPDSLAKIRELESLQGA 3269
                + K+R  E+ +GA
Sbjct: 3273 PAQFIGKLRNKEATEGA 3289



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 91/367 (24%), Positives = 140/367 (38%), Gaps = 27/367 (7%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR-ITSIFNFGYV 828
            P F+  LQ+  E+Q+G    F+  +T    P   V W+KDG+ +      + +    G  
Sbjct: 5126 PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXX 888
             L I  +   D G Y   A N +G + + A +RV   ST   D                 
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTST---DYDTAADATESSSYFSAQ 5239

Query: 889  XXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKD 948
                           +  Q P+    ++D         A F+ +++  G    R+ W KD
Sbjct: 5240 GYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFKD 5297

Query: 949  GRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
            G+P+ AS+ I          L I SVT  D+G Y     NA+G A +SA L +V   D  
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL-LVRGPD-- 5354

Query: 1009 AESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVE 1068
             E +     +  + L       + T ++VK      F   ++G        + H+  R E
Sbjct: 5355 -EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR----PVPTVHW-LREE 5408

Query: 1069 PQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQ 1128
             +      V W   G          +      V LD+     +  G YT +A NAAG+A 
Sbjct: 5409 AERG----VLWI--GPDTPGYTVASSAQQHSLVLLDVG---RQHQGTYTCIASNAAGQAL 5459

Query: 1129 LSASMTV 1135
             SAS+ V
Sbjct: 5460 CSASLHV 5466



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 78/337 (23%), Positives = 123/337 (36%), Gaps = 56/337 (16%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+   +P+   +  G DA    Q+ GNP P+V+W K+ Q +    +  +    +   L +
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
            +    DSG Y   A N  G    +  L V++  E+   +Q   ++              
Sbjct: 70  LDLALGDSGQYVCRARNAIGEAFAAVGLQVDA--EAACAEQAPHFL-------------- 113

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE- 444
               L P  ++V       EG    F CRV G P P V+W  + R++ +    ++ V E 
Sbjct: 114 ----LRPTSIRV------REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 445 ---------------SGNHALMITNVTLSDSGVVTCVARNKSGETA-------------F 476
                           G + +   N   + S     V  + + +TA              
Sbjct: 164 GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHL 223

Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536
           Q R   +  E   A        T  V EG+   L+    G P P   W+KDG  +     
Sbjct: 224 QRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR 283

Query: 537 LRIHTDGGAS-TLDIPRAKASDAAWYQCTAQNVAGST 572
             ++ D   +  L I   K SD   Y CTA N+ G T
Sbjct: 284 HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 68/236 (28%), Positives = 104/236 (44%), Gaps = 18/236 (7%)

Query: 1041 QKPRFLGPLKGTN-KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN--RIQTYHD 1097
            Q P FL  L+ T+ ++ EG  A F  RV         V W  +G+++   +  R++    
Sbjct: 108  QAPHFL--LRPTSIRVREGSEATFRCRVGGSP--RPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
                AL I + R  D G Y V A N  G A  +A++ V++ ++   S           H+
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHL 223

Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
            +  +  E M + E    S P      +    V+EGK+  L C +   G+P     W  +G
Sbjct: 224  QRRR--EAM-RAEGAPASPP---STGTRTCTVTEGKHARLSCYVT--GEPKPETVWKKDG 275

Query: 1218 RSVTVGSRFKTYYDF--GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            + VT G R   Y D    FV L I+    +D G YT  A N +G  ++S +V V E
Sbjct: 276  QLVTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 38/130 (29%), Positives = 68/130 (52%), Gaps = 6/130 (4%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V   PRF+ ++   +   EG+ A + C IE  P P +R  WY +G +L +G++++T 
Sbjct: 6101 KILVQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTL 6157

Query: 1897 ND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH-ESALE 1953
            ++   G   L I     ED G Y C+ +N LG A +S  L +QS     ++  H E  + 
Sbjct: 6158 SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVA 6217

Query: 1954 KIQYLEDDSR 1963
             ++  E +++
Sbjct: 6218 AVEVTEQETK 6227



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 17/241 (7%)

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGASTL 548
            AP F+       V++G PV  +    G P P + W KDG  +  +    I+ D  G   L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXX 608
             I     +D   Y+C A+N  G ++T+A L                              
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDT---------AADATESSSY 5235

Query: 609  XXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKI-HFETRIEPVGDPT 667
                 YL   E+        E       PQ +  L+ +    G ++  F+ +++  G P 
Sbjct: 5236 FSAQGYLSSREQEGTESTTDEGQL----PQVVEELRDLQVAPGTRLAKFQLKVK--GYPA 5289

Query: 668  MKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLH 727
             ++ W K+GQ + AS+      +    +L+++S+  +DSG+Y     +A G A + A L 
Sbjct: 5290 PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLL 5349

Query: 728  V 728
            V
Sbjct: 5350 V 5350



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 90/382 (23%), Positives = 154/382 (40%), Gaps = 32/382 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL-KVEWFKNGQPVTIGHRFRPIHDF-GY 1501
            P F+T  ++ E V +G  V F+C    VT   +  V WFK+G+ +     +    D  G 
Sbjct: 5126 PVFLTELQNQE-VQDGYPVSFDCV---VTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST-TDI---VRSTQNEAGLEQIQV 1557
              L I  ++  D G+Y C A N +G       L    T TD      +T++ +       
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 1558 LEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR-AHFERRLIPVSDATLKVEWYHN 1616
            L  R +       DE   Q P     L+++++  G R A F+ ++        ++ W+ +
Sbjct: 5242 LSSREQEGTESTTDE--GQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKD 5297

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY 1676
             +PL + +    T+      L+I+S   EDSG Y     NA+G A +S   +V       
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD--- 5354

Query: 1677 LESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
             E + + A     QL      +R + +      +  F++ ++   V        EA    
Sbjct: 5355 -EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---- 5409

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
                +  V W+    P          H     +L +  V  +  GTYTC A N  G+A+ 
Sbjct: 5410 ----ERGVLWIGPDTPGYTVASSAQQH-----SLVLLDVGRQHQGTYTCIASNAAGQALC 5460

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
            S++L V     ++ + + + AL
Sbjct: 5461 SASLHVSGLPKVEEQEKVKEAL 5482



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 90/366 (24%), Positives = 137/366 (37%), Gaps = 46/366 (12%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PRF+TRPK+   V  G+     C++  V +   +V W K+ QPV  G RFR         
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFR--------- 57

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
                  +A+D  +Y    ++L   D  S +  CR+   I  +     GL+          
Sbjct: 58   ------LAQDGDLYRLTILDLALGD--SGQYVCRARNAIGEAFA-AVGLQ---------- 98

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPL--K 1621
                D       QAP       ++ ++EG  A F  R+         V W  + + L   
Sbjct: 99   ---VDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRV--GGSPRPAVSWSKDGRRLGEP 153

Query: 1622 SGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQH 1681
             G R          AL I +  P D GTY  RA N LG A  +   +V S  +       
Sbjct: 154  DGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPG 213

Query: 1682 EGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPK 1741
                  L  L+     +R + + E    +P  T   +   V E + A     +   G+PK
Sbjct: 214  TSTAALLAHLQ----RRREAMRAEGAPASPPST-GTRTCTVTEGKHARLSCYV--TGEPK 266

Query: 1742 LRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
                W ++G  +    R     D      L + +    D G YTC A N +G+  +S  +
Sbjct: 267  PETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326

Query: 1801 FVQSKA 1806
             V+  A
Sbjct: 327  VVREPA 332



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 63/221 (28%), Positives = 88/221 (39%), Gaps = 13/221 (5%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KTGHRFRPAYEFD 1366
            QAP F     +I   EG+     CR+   G     V W  +G+ +    G R R     +
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426
              AL + +  P D G Y  +A N LG A  S A  ++   D    +  P G      L  
Sbjct: 166  ASALRIRAARPRDGGTYEVRAENPLGAA--SAAAALVVDSDAADTASRP-GTSTAALLAH 222

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
              R ++    + +    P   TR  +   V EG+H    C +    +   +  W K+GQ 
Sbjct: 223  LQRRREAMRAEGAPASPPSTGTRTCT---VTEGKHARLSCYV--TGEPKPETVWKKDGQL 277

Query: 1487 VTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            VT G R     D      L I+     D G+YTC A NLVG
Sbjct: 278  VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 89/404 (22%), Positives = 157/404 (38%), Gaps = 50/404 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            KP +F++++    + E E      E     +P+  W ++   ++ S   Q+     ++ L
Sbjct: 3094 KPSVFSRELTDATITEGEDLTLVCETSTCDIPVC-WTKDGKTLRGSARCQLSHEGHRAQL 3152

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +I    ++DS  +   A   GG   CS+++V    R        P  F    +++ V  G
Sbjct: 3153 LITGATLQDSGRYKCEA---GGA--CSSSIVRVHAR--------PVRFQEALKDLEVLEG 3199

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                L   V  +    V W      ++P  +  + +E     L++    PQDSG+Y C  
Sbjct: 3200 GAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC-- 3256

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
              S G+    A   V+                 P + I  L++K   EG      C++  
Sbjct: 3257 --SFGDQTTSATLTVTA---------------LPAQFIGKLRNKEATEGATATLRCEL-S 3298

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            K  P V+W KG + ++    + + +      L+I      D  +Y CV     G    +A
Sbjct: 3299 KAAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCV----CGEERTSA 3353

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L + +P  A  +  L     I   EG  A  + ++ SK  P ++W +    + +     
Sbjct: 3354 SLTI-RPMPAHFIGRLRHQESI---EGATATLRCEL-SKAAP-VEWRKGRESLRDGDRHS 3407

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +  +G    L I      D G ++C      G+  TSA L VK+
Sbjct: 3408 LRQDGAVCELQICGLAVADAGEYSC----VCGEERTSATLTVKA 3447



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 13/222 (5%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            +PP F +++  C     E  +      G P P+I WY++   ++  P    I        
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI+  +   DS  +   A +  G       ++V+          VPP F    +      
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----------VPPRFVNKVRASPFVE 6121

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLILEAYPQDSGKYE 4585
            G+  +    + G     + W K+G  +    + + L E   G   L+I  A  +D G YE
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            C  +N  G AR  AE  +  P  + + +   +   A  E+ E
Sbjct: 6182 CELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 6223



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 64/236 (27%), Positives = 102/236 (43%), Gaps = 12/236 (5%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTFFN 963
            S   P F T +++Q  +++G    F+  +   G     V W KDG+ +E     +     
Sbjct: 5122 SDAAPVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI---VTKKDIIAESQHPGGLEKI 1020
             G   L I +V   D G Y C A N++G ++T A L +    T  D  A++         
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238

Query: 1021 Q-YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEW 1079
            Q YL  +SR  + TE      Q P+ +  L+        + A F+ +V+        + W
Sbjct: 5239 QGYL--SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYP--APRLYW 5294

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            + +G+ +T++  I+         L+I SV  EDSG Y     NA G A  SA + V
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 62/213 (29%), Positives = 86/213 (40%), Gaps = 14/213 (6%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV--GSRFKTYYDFGFVALDIIHATSAD 1246
            V EG      CR+   G P   V W  +GR +    G R +        AL I  A   D
Sbjct: 121  VREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT 1306
             G Y VRA N LG+A  SA   ++  SD   DT +        LL    RR + +R +  
Sbjct: 179  GGTYEVRAENPLGAA--SAAAALVVDSD-AADTASRPGTSTAALLAHLQRRREAMRAEGA 235

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF- 1365
                P  S         EG +  L C +   G+      W  +G+ +  G R    YE  
Sbjct: 236  PASPP--STGTRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQLVTEGRR-HVVYEDA 290

Query: 1366 -DYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             +   L +L     D G+YTC A+N +G+  +S
Sbjct: 291  QENFVLKILFCKQSDRGLYTCTASNLVGQTYSS 323



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 101/447 (22%), Positives = 171/447 (38%), Gaps = 48/447 (10%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P F T   +  + +     F+C  +        V WF +GK L          D  G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V   D G+Y C A N  G ++   +L+V     +       +   + + S    +
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVD----LTSTDYDTAADATESSSYFSAQ 5239

Query: 3677 ETLHKREEITIED--EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
              L  RE+   E   ++   P+   E++D    P      F  +V+  G P  R+ WF +
Sbjct: 5240 GYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFKD 5297

Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            G+P    + +   +      L+I  +   D+G+Y    +N  G+A ++A++         
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL--------- 5348

Query: 3795 LESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVE 3854
                L +G       E E    SD    E +V  PP+ + +     V++   + F  +VE
Sbjct: 5349 ----LVRGPD-----EPEEKPASDV--HEQLV--PPRMLERFTPKKVKKGSSITFSVKVE 5395

Query: 3855 PKEDPKLRIEWYR----NGKLL--PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
             +  P   + W R     G L   P    Y         SL +L V  +  G Y C A N
Sbjct: 5396 GRPVP--TVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASN 5453

Query: 3909 DFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTED--DLYD 3966
              G+    A++    LP +  Q +V    K +   T ++ T +  +++   T    DL  
Sbjct: 5454 AAGQALCSASLHVSGLPKVEEQEKV----KEALISTFLQGTTQAISAQGLETASFADL-G 5508

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKF 3993
              +K+ P    +     SL E+ T +F
Sbjct: 5509 GQRKEEPLAAKEALGHLSLAEVGTEEF 5535



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 73/324 (22%), Positives = 126/324 (38%), Gaps = 29/324 (8%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P   + W+ +GK+LE+   + +  D  G   L +  V   D G+Y C A N  G + T +
Sbjct: 5153 PMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKA 5212

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD 3059
             +         +       +      Q    S R++ G +   D G+ P+     +D+  
Sbjct: 5213 ELRVDLTSTDYDTAADATESSSYFSAQGYLSS-REQEGTESTTDEGQLPQVVEELRDLQV 5271

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
                ++A ++  +   G  +  + WF +G+ + AS  IR      +  LEI+     DSG
Sbjct: 5272 APGTRLAKFQLKV--KGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSG 5329

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNI----------EGLKDGQSAH 3168
             Y+   +N  G A  S +L      +  +KP    H Q +          + +K G S  
Sbjct: 5330 QYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSIT 5389

Query: 3169 FECTV----VPV-----DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
            F   V    VP      ++ +  + W   G      T   +      V+LD+   + H  
Sbjct: 5390 FSVKVEGRPVPTVHWLREEAERGVLWI--GPDTPGYTVASSAQQHSLVLLDVG--RQH-Q 5444

Query: 3220 GEYVCRAYNKYGEDFTRATINCYG 3243
            G Y C A N  G+    A+++  G
Sbjct: 5445 GTYTCIASNAAGQALCSASLHVSG 5468



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 82/373 (21%), Positives = 150/373 (40%), Gaps = 54/373 (14%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W + +  +++   + +    TK  L IR + + D+  ++ V     G  + SA L V 
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVC----GQERTSAMLTVR 3622

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
                      +P  FT   +N   T G    L  +++   P++  W K  + ++   R+ 
Sbjct: 3623 A---------LPIKFTEGLRNEEATEGATAVLRCELSKMAPVE--WWKGHETLRDGDRHS 3671

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            + ++     L I     +D+G+Y C+     G+ R  A   V                  
Sbjct: 3672 LRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRA---------------M 3712

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P + IE L+++   EG      C++  K  P V+W KG + ++      + +      L+
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCEL-SKAAP-VEWRKGHETLRDGDRHSLRQDGSRCELQ 3770

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQ 4739
            I      D G+Y CV     G+   +A L V        LPA  +  +++    EG  A 
Sbjct: 3771 IRGLAVVDAGEYSCV----CGQERTSATLTVRA------LPARFIEDVKNQEAREGATAV 3820

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
             + ++ SK  P ++W +    +     + +  +G    L I      DTG ++C      
Sbjct: 3821 LQCEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC----VC 3874

Query: 4800 GQVETSAKLVVKS 4812
            GQ  TSA L V++
Sbjct: 3875 GQERTSATLTVRA 3887



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 6/133 (4%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD- 3883
            +V  PP+F+ ++++    E E  +F C +E    P++R  WY++G LL +G++++T+ + 
Sbjct: 6103 LVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 6160

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR-GMKRSE 3941
              G + L I     ED G Y C  VN  G     A +  +  P +  Q Q  R  +  + 
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS-PMLQAQEQCHREQLVAAV 6219

Query: 3942 ALTQMEATIKKYT 3954
             +T+ E  + K T
Sbjct: 6220 EVTEQETKVPKKT 6232



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 3/122 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
            PP+   K R S   EG DAQF   + G P P++ W+K+G  L   NK + ++        
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 6166

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP-TESYVQDQRSQYITDTQQRETEE 381
            L +R   K D G Y     N  G    S  L ++SP  ++  Q  R Q +   +  E E 
Sbjct: 6167 LVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQET 6226

Query: 382  RI 383
            ++
Sbjct: 6227 KV 6228



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 61/238 (25%), Positives = 105/238 (44%), Gaps = 15/238 (6%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GF 3477
            APVF   L N E +++G    F+  +T    P+  V W+ +GK L+    +    D  G 
Sbjct: 5125 APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPS--VRWFKDGKLLEEDDHYMINEDQQGG 5181

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIA 3536
              L I+   P D G Y C A N+ G + T A ++V      +  +      + T      
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-----LTSTDYDTAADATESSSYF 5236

Query: 3537 ALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSS-AHFECRLIPVNDSSMRVEW 3593
            + +GY  + +    E+  + G  P+      DL ++  +  A F+ ++      + R+ W
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYW 5294

Query: 3594 FHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            F +G+PL   + ++  +      LEI  V + D+G Y    +N  G A  S +L V+G
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 58/219 (26%), Positives = 95/219 (43%), Gaps = 16/219 (7%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            + V + P  FSR L ++ T E   V LEC L       + V W  +G  ++ G     A 
Sbjct: 2159 LVVTELPVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAA 2215

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK-DLILESQHPSGLEKIQ 1422
            +    +L +      D GVY C A     +A +S +++V  +   LI          +IQ
Sbjct: 2216 QGACRSLTIYRCEFADQGVYVCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQ 2271

Query: 1423 YLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK 1482
            ++ + +  +    + E     P  + RP   +  +E      EC+   V+ ++ +V WFK
Sbjct: 2272 FVAENAESRAQLRVKEL----PVTLVRPLRDKIAMEKHRGVLECQ---VSRASAQVRWFK 2324

Query: 1483 NGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
              Q +  G ++  + D  Y  L I D+ AED   YTC A
Sbjct: 2325 GSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 63/255 (24%), Positives = 108/255 (42%), Gaps = 28/255 (10%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            V WLK+G +++   R++   +  T+TL +  A   DS  Y C         R  AE    
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC---------RVGAE---- 1796

Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
                +D P    + A     ++EP+  ++   G  +  +C++       V W  G+  ++
Sbjct: 1797 ---GQDFPVQVEEVAAKFCRLLEPVCGEL---GGTVTLACEL-SPACAEVVWRCGNTQLR 1849

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
              K FQM       +L +     ED G+Y C + +       +A+L V+ P     +  +
Sbjct: 1850 VGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDD----HTSAQLTVSVPRV---VKFM 1902

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
            + L  +V  EG  A F+  + S     + W R+GAL+  +  F +   G +  L I +  
Sbjct: 1903 SGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLV 1961

Query: 4785 EEDTGTFTCRATTAA 4799
             ED G  T  A  A+
Sbjct: 1962 LEDAGQITVEAEGAS 1976



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 50/203 (24%), Positives = 86/203 (42%), Gaps = 12/203 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            E + V LE ++   + PN+ + W K+GV L  G  +         +L+I      D G+Y
Sbjct: 2179 EKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVY 2235

Query: 2716 TCKATNLLGEAVSTASIKIEDRHW-LLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXX 2774
             C A     +A S+AS+K++ R + L+   +  +    I  +                  
Sbjct: 2236 VCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVT 2291

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            + +  L + +  E      EC V  +   + ++ WF  ++ L  G +Y+   D  Y  L 
Sbjct: 2292 L-VRPLRDKIAMEKHRGVLECQVSRA---SAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347

Query: 2835 ITHTYEEDSGIYTCKATNSKGSA 2857
            I+  + ED   YTC A + K SA
Sbjct: 2348 ISDVHAEDEDTYTCDAGDVKTSA 2370



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 59/261 (22%), Positives = 108/261 (41%), Gaps = 29/261 (11%)

Query: 1700 HSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            H++   V+T+ PV F+ P++D+   E +    E  L     P + V WL++GV + A   
Sbjct: 2154 HTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKT 2210

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            +         +L +      D G Y C A +             QS AS++++ +  + +
Sbjct: 2211 MAIAAQGACRSLTIYRCEFADQGVYVCDAHD------------AQSSASVKVQGRTYTLI 2258

Query: 1819 QKIQQLEDSSRYQ-----RREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPD 1873
             +    ED+   Q          ++ V + P  + +        E      EC++     
Sbjct: 2259 YRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSR--- 2315

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             + +V W+   + LQ G +Y   +D  +  L I  V+ ED   YTC A    G   +S +
Sbjct: 2316 ASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQ 2371

Query: 1934 LNVQSKE-SIIRDSQHESALE 1953
              V+ +  +I+R  Q  + +E
Sbjct: 2372 FFVEEQSITIVRGLQDVTVME 2392



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 49/180 (27%), Positives = 78/180 (43%), Gaps = 15/180 (8%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            QD + TE     F C ++     EV W +N   + +D  H+I  ++   H L++ ++  +
Sbjct: 2565 QDAEATEEGWASFSCELSHED-EEVEWSLNGMPLYNDSFHEIS-HKGRRHTLVLKSIQRA 2622

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G+V    R  S + +   RL V  K  V    F++    L+  E   + L    V  P
Sbjct: 2623 DAGIV----RASSLKVSTSARLEVRVKPVV----FLKALDDLSAEERGTLALQCE-VSDP 2673

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               + W+KDGV + P+ +       G   L +      DA  Y C      GS  TRAR+
Sbjct: 2674 EAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARV 2729



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 60/234 (25%), Positives = 95/234 (40%), Gaps = 8/234 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIV 3340
            P F+T++Q+  ++ +G    F+   V    P   V WF +GK L     Y    D  G  
Sbjct: 5126 PVFLTELQN-QEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400
             L I      + G Y C+A N +G  STKA L+     +   D+             Q  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELR-VDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
              S   ++ T    ++G+ P     L +++       A F+ ++     P L   W+ +G
Sbjct: 5242 LSSR-EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRL--YWFKDG 5298

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            + L A +  R         LEI     EDSG+Y     N  G A ++A + V+G
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 65/284 (22%), Positives = 116/284 (40%), Gaps = 28/284 (9%)

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            ++ V   +G    L  +V   +  +V W K+GKK+    + ++     T  L++ EA   
Sbjct: 1541 SREVQAEAGTSATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQA 1599

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQ 4638
            D+G+Y C     AG+ R      V+ P          K   A  +   P   ++ AE G 
Sbjct: 1600 DAGEYSC----KAGDQRLSFHLHVAEP----------KVVFAKEQ---PAHREVQAEAGA 1642

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            +   SC+ V +    V WYK  K +  S   ++        L + +A   + G+Y C   
Sbjct: 1643 SATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSC--- 1698

Query: 4699 NSAGRVTVAAKLKVTQPD-QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
              AG   ++ +L+V + + Q    P       +VV E +       + +    T+ WL++
Sbjct: 1699 -EAGGQQLSFRLQVAELEPQISERPCRR--EPLVVKEHEDIILTATLATPSAATVTWLKD 1755

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
            G  I  +   +   +G+   L +      D+  ++CR   A GQ
Sbjct: 1756 GVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCR-VGAEGQ 1798



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 101/402 (25%), Positives = 157/402 (39%), Gaps = 48/402 (11%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLP-LIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            TK+++   V E E   FE     E       W      + +S  FQ      K IL++R+
Sbjct: 2739 TKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVRE 2798

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
                D+     V   RG T+K  A+L+V E+       I+ P   L  Q V       +R
Sbjct: 2799 AAPSDAG--EVVFSVRGLTSK--ASLIVRERP----AAIIKP---LEDQWVAPGEDVELR 2847

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
             +    GT    V+WLK+ K ++   +  ++ E GT  +L++             ++  A
Sbjct: 2848 CELSRAGTP---VHWLKDRKAIRKSQKYDVVCE-GTMAMLVIRG----------ASLKDA 2893

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
            GE  C+ E   S  +   + K     AN   E +  L+  +  +G A+ F+CK    P  
Sbjct: 2894 GEYTCEVEASKSTASLHVEEK-----ANCFTEELTNLQ--VEEKGTAV-FTCK-TEHPAA 2944

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            TV W KG   ++ S   Q S+      L IS     D   Y C      G+    A+L V
Sbjct: 2945 TVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLV 3000

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM-IH 4771
                Q   +  +  L D+ V EG  A F+ +I+      + W  +   +      ++   
Sbjct: 3001 ----QGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQ 3056

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             G   VL +     +D+GT        AG    SA L V  K
Sbjct: 3057 PGGYHVLTLRQLALKDSGTIYFE----AGDQRASAALRVTEK 3094



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 49/189 (25%), Positives = 77/189 (40%), Gaps = 14/189 (7%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS-HRIRTVYAFG 3104
            RPP+F    +++ D +       + +   TG    VI W+ +GK ++   H I      G
Sbjct: 6012 RPPDFE---EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG 6068

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +      DSG Y C A +  G      K+          PRF   ++      +G
Sbjct: 6069 SCALILDSLTGVDSGQYMCFAASAAGNCSTLGKI-----LVQVPPRFVNKVR-ASPFVEG 6122

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEY 3222
            + A F CT+     P  +I WY +G  +    + +T+S+   G +VL I      D G Y
Sbjct: 6123 EDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 6180

Query: 3223 VCRAYNKYG 3231
             C   N+ G
Sbjct: 6181 ECELVNRLG 6189



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 78/361 (21%), Positives = 140/361 (38%), Gaps = 38/361 (10%)

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
            +P   + WY++   + +S   ++        L+++QV   D+  ++  A    G  + S 
Sbjct: 1192 QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSF 1247

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             L + E +       V     L    V   +G    L  +V   +  +V W K+GKK+  
Sbjct: 1248 QLHITEPKA------VFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSS 1300

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
              + +I        L++ +A   D+G+Y C     AG  R      VS P          
Sbjct: 1301 SSKVRIEAAGCMRQLVVQQAGQADAGEYTC----EAGGQRLSFHLDVSEP---------- 1346

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIE-FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675
            KA  A  ++      K+ AE  AI   SC+ V +    V WYK  K +  S   +M    
Sbjct: 1347 KAVFAKEQLAHR---KVQAEAGAIATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRMEAVG 1402

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RDIVVYE 4734
                L + +A   D G+Y C     AG   ++  L V +P          P+ R++    
Sbjct: 1403 CTRRLVVQQACQADTGEYSC----EAGGQRLSFSLDVAEPKVV--FAKEQPVHREVQAQA 1456

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G       ++ ++ +  + W ++G  +  +   +M   G    L++    +   G ++C 
Sbjct: 1457 GASTTLSCEV-AQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCE 1515

Query: 4795 A 4795
            A
Sbjct: 1516 A 1516



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 76/357 (21%), Positives = 142/357 (39%), Gaps = 40/357 (11%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S   ++        L+++Q    D+  ++  A    G  + S +L V 
Sbjct: 1381 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVA 1436

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E +      +V        + V   +G    L  +V   +  +V W K+GKK+    + +
Sbjct: 1437 EPK------VVFAKEQPVHREVQAQAGASTTLSCEVAQAQT-EVMWYKDGKKLSFSSKVR 1489

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +     T  L++ +A    +G+Y C     AG  R      V+ P          KA  A
Sbjct: 1490 MEAVGCTRRLVVQQAGQAVAGEYSC----EAGSQRLSFHLHVAEP----------KAVFA 1535

Query: 4622 PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
              +   P   ++ AE G +   SC+ V +    V WYK  K +  S   +M        L
Sbjct: 1536 KEQ---PASREVQAEAGTSATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRL 1591

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ--ADNLPALTPLRDIVVYEGQPA 4738
             + EA   D G+Y C     AG   ++  L V +P    A   PA    R++    G  A
Sbjct: 1592 VVQEAGQADAGEYSC----KAGDQRLSFHLHVAEPKVVFAKEQPA---HREVQAEAGASA 1644

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
                ++ ++ +  + W ++G  +  +   ++   G    L++    + + G ++C A
Sbjct: 1645 TLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEA 1700



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 59/230 (25%), Positives = 95/230 (41%), Gaps = 8/230 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFV 2566
            P+F   L    E+ +G    ++  V     PS+R  W+ +G  L+    +    D  G  
Sbjct: 5126 PVFLTELQN-QEVQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAM-RPESWEQIQLKEAA 2625
             L I +VV  D G+Y C A N  G                 D A    ES      +   
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 2626 MNKVPEMFVDTGVQ-QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684
             ++  E    T  + Q P     L+   ++  G  +  + Q++ +  P  ++ WFK+G  
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDL-QVAPGTRL-AKFQLKVKGYPAPRLYWFKDGQP 5300

Query: 2685 LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            LT  A ++ T    L TL I S+  +DSG Y    +N +G A S+A + +
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 53/211 (25%), Positives = 88/211 (41%), Gaps = 10/211 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYV 4031
            P F+T++Q+Q  + +     F+C +   G P   V WF +GK L   + +    D  G  
Sbjct: 5126 PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE-- 4089
             +    V P D G Y C A N  G+  TKA ++        YD+       S     +  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-LTSTDYDTAADATESSSYFSAQGY 5241

Query: 4090 MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            + +  Q   E   +E +   P V   L D         A+F  +V G+P PR+ W  +G 
Sbjct: 5242 LSSREQEGTESTTDEGQL--PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQ 5299

Query: 4150 TIVNGSRYKLTYDGMYH-FDIPKTRQYDTGK 4179
             +   +  ++T   + H  +I    + D+G+
Sbjct: 5300 PLTASAHIRMTDKKILHTLEIISVTREDSGQ 5330



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+F           G +  L C++  VG+ T +V W  + +P+  G RFR A + D   
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
            L +L +   DSG Y C+A N +GEA  +  L+V A+     ++ H
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 64/252 (25%), Positives = 101/252 (40%), Gaps = 21/252 (8%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F+ PL ++    E E    E  L+    PN+ V W  +G  L+AG             L 
Sbjct: 2168 FSRPLQDVVTT-EKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGY 3541
            I      D G Y+C A+    +A ++AS+KVQG+   ++  ++     G I  +A  E  
Sbjct: 2224 IYRCEFADQGVYVCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVA--ENA 2277

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
                     E     P        D I  E      EC+   V+ +S +V WF   + L 
Sbjct: 2278 ESRAQLRVKEL----PVTLVRPLRDKIAMEKHRGVLECQ---VSRASAQVRWFKGSQELQ 2330

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ----VKGRQGIIL 3657
             G + + ++D  +  L I  V+  D   YTC A +    A    + Q    V+G Q + +
Sbjct: 2331 PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTV 2390

Query: 3658 EPQLPSHFKSGT 3669
                P+ F+  T
Sbjct: 2391 MEPAPAWFECET 2402



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 33/106 (31%), Positives = 57/106 (53%), Gaps = 3/106 (2%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            APRF+T+      +S G+ A   C+I   P P  +V W  + + + +G R+R + D    
Sbjct: 9    APRFLTRPKAFV-VSVGKDATLSCQIVGNPTP--QVSWEKDQQPVAAGARFRLAQDGDLY 65

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
             L IL +   DSG+Y C+A N +G+A +++ L V ++ +    + H
Sbjct: 66   RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 72/355 (20%), Positives = 139/355 (39%), Gaps = 36/355 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S    +     +  L+++Q    D+  ++   E RG       + + E
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC--EARGQRVSFRLH-ITE 1069

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
             K    +   V       A    + S ++ +  T+VT        W K+GKK+    +  
Sbjct: 1070 PKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVT--------WYKDGKKLSSSSKVG 1121

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +  +  T  L++ +A   D+G+Y C     AG  R      ++ P          K   A
Sbjct: 1122 MEVKGCTRRLVLPQAGKADAGEYSC----EAGGQRVSFHLHITEP----------KGVFA 1167

Query: 4622 PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
              + +    +++ AE G     SC+ V +P   V WYK  K +  S   +M        L
Sbjct: 1168 KEQSVH---NEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRL 1223

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             + +    D G+Y C     AG   V+ +L +T+P        L    ++    G  A  
Sbjct: 1224 VVQQVGKADAGEYSC----EAGGQRVSFQLHITEPKAVFAKEQLVH-NEVRTEAGASATL 1278

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
              ++ ++ +  + W ++G  +  +   ++   G    L++    + D G +TC A
Sbjct: 1279 SCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 143/711 (20%), Positives = 251/711 (35%), Gaps = 54/711 (7%)

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLT 4160
            E + A   P F+  P ++ V EG  A F CRV G P+P V W  +G  +   +G R ++ 
Sbjct: 102  EAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVE 161

Query: 4161 YDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR---GVLKNAPRP 4216
              G      I   R  D G  EV              L V     D     G    A   
Sbjct: 162  ELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLA 221

Query: 4217 WYDETTQYQRTE--TELEKTFEERQVLQRQGVIDHRPELKPKVIKEP--ETEWQQSVKRK 4272
                  +  R E       +   R     +G       L   V  EP  ET W++  +  
Sbjct: 222  HLQRRREAMRAEGAPASPPSTGTRTCTVTEG---KHARLSCYVTGEPKPETVWKKDGQLV 278

Query: 4273 KNEEYYNKLQELENEQVIKESRLRESTH-QYAIPGDKVTSNTVAKSMAQRYEDNLDQTEE 4331
                 +   ++ +   V+K    ++S    Y      +   T +  +    E  +   + 
Sbjct: 279  TEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKR 338

Query: 4332 VTEQRVQKK--VTQKPRIPDPS-ESTVHGKEVHV-AKQKQTQKEVVGDKEITRKITSTET 4387
            + +  V++K   T    +P PS E+    +E  + A  K   +E   ++ +T +  S + 
Sbjct: 339  LQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADD 398

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
              + +  +T E          +  +  K  +   V   + A F VE    P+  + W R 
Sbjct: 399  DAV-YICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVEL-AVPVGPVHWLRN 456

Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
               +       I    T+  L I Q  +ED    A +A    G  + S    V   R+  
Sbjct: 457  QEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMA----GDCQTSTQFCVSAPRKP- 511

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP--IDVYWLKNGK-KVQPDIRNKILE 4564
               + PP   +      + S  ++       G +P  ID Y ++  K      IR    E
Sbjct: 512  --PLQPPVDPVV--KARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAE 567

Query: 4565 EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD-KPKPQTKAANAPP 4623
               T  L + +   + + ++   A+NS G++       +  P T    PK   +      
Sbjct: 568  WVATPELTVADVAEEGNFQFRVSALNSFGQSP-----YLEFPGTVHLAPKLAVRT----- 617

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
                PLK     EG  + FS  +        +W+   + +K S  +++      +TL I 
Sbjct: 618  ----PLKAVQAVEGGEVTFSVDLT--VASAGEWFLDGQALKASSVYEIHCDRTRHTLTIR 671

Query: 4684 EAFPEDEG-DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
            E      G   K VA      + +  +     P    N P     R+++    + AQ   
Sbjct: 672  EVPASLHGAQLKFVANGIESSIRMEVR---AAPGLTANKPPAAAAREVLARLHEEAQLLA 728

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +++ +    + WL++G  +   P +++       VLL+ +   +D G + C
Sbjct: 729  ELSDQ-AAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 69/275 (25%), Positives = 110/275 (40%), Gaps = 25/275 (9%)

Query: 1974 VVEKP-QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P  F +P+++   TE   V LE  L+    P + V W  +G  ++ G         
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQG 2217

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG--LYLDTLDEQRLKKIQE 2090
               +L I      D G Y+C A +A   A    SVKV  ++   +Y   L E    +IQ 
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDAQSSA----SVKVQGRTYTLIYRRVLAEDA-GEIQF 2272

Query: 2091 LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQ 2150
            +   E  +   + +  + PV L      +   E  R   EC+V   +     + WF   Q
Sbjct: 2273 VA--ENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRAS---AQVRWFKGSQ 2327

Query: 2151 KIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILD 2210
            +++ G +Y    D  Y  L I   +AED  TY C A +     V T        ++I + 
Sbjct: 2328 ELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD-----VKTSAQFFVEEQSITI- 2381

Query: 2211 TQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV 2245
                 GL+ +  +E        E   P + PP+++
Sbjct: 2382 ---VRGLQDVTVMEPAPAWFECETSIPSVRPPKWL 2413



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 5/115 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            VQ  P F   +++    VEG+       +E    P  +I W+K+G  LTTG + ++  + 
Sbjct: 6104 VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEP 6160

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
              GL+ L I +   +D G+Y C+  N LG A ++A ++I+       E  H + L
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL 6215



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 4/128 (3%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
            ++P  S  P+F+T+ K+  V   +     C++     P+  + W ++ + + +G R+R  
Sbjct: 2    DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQ--VSWEKDQQPVAAGARFRLA 59

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSE 3941
             D     L IL +   DSG+Y+CRA N  GE F  A +  +   +     Q P  + R  
Sbjct: 60   QDGDLYRLTILDLALGDSGQYVCRARNAIGEAF--AAVGLQVDAEAACAEQAPHFLLRPT 117

Query: 3942 ALTQMEAT 3949
            ++   E +
Sbjct: 118  SIRVREGS 125



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 91/404 (22%), Positives = 155/404 (38%), Gaps = 48/404 (11%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFV 3207
            P F T +QN E ++DG    F+C V     P   + W+ +G+ +          D  G  
Sbjct: 5126 PVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQ 3267
             L I      D G Y C A N  G   T+A +       V L S   D+ A   E  S  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELR------VDLTSTDYDTAADATESSSYF 5236

Query: 3268 GAQQQTPS---------TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEW 3318
             AQ    S         T   + P+ + +++D+      + A F+ ++     P  ++ W
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYW 5294

Query: 3319 FYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            F +G+ L      R      +  L+I+    E+SG+Y    +N +G   + A L      
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL------ 5348

Query: 3379 NLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENA 3438
             L+     P          Q +   M+ R  T  + +KG +  F+V +      R     
Sbjct: 5349 -LVRGPDEPEEKPASDVHEQLVPPRMLER-FTPKKVKKGSSITFSVKVEG----RPVPTV 5402

Query: 3439 HFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAY 3498
            H+   L    +  +     W G      +   +      V+L++     +  G Y C A 
Sbjct: 5403 HW---LREEAERGV----LWIGPDTPGYTVASSAQQHSLVLLDVG---RQHQGTYTCIAS 5452

Query: 3499 NNYGEAVTTASMKVQG-----KRNIILESQLPKGMEGTIDKIAA 3537
            N  G+A+ +AS+ V G     ++  + E+ +   ++GT   I+A
Sbjct: 5453 NAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISA 5496



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 10/146 (6%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FGF 1234
            P FV  +   P V EG++    C +E  G P  ++ W+ +G  +T G++F+T  +   G 
Sbjct: 6108 PRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQLLED 1293
            + L I  A+  D G Y    VN LGSA  SA +R+             EQ +  +++ E 
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQ 6224

Query: 1294 ---AARRTKQVREDI-TVMQAPQFSR 1315
                 ++T  + E I TV+++P+  R
Sbjct: 6225 ETKVPKKTVIIEETITTVVKSPRGQR 6250



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 51/241 (21%), Positives = 103/241 (42%), Gaps = 24/241 (9%)

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            R  NTQ      + ++AE P   +   G  A ++           +Y+ +++   T  ++
Sbjct: 1842 RCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDA----------GEYVCESRDDHTSAQL 1891

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
             +S   +  +F+         EG    F C V+      V WF +   ++   + K  ++
Sbjct: 1892 TVSVPRVV-KFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQP--SEKFAIS 1947

Query: 444  ESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +SG +H+L I+++ L D+G +T  A   S   A + R   +  ++ + P+ VE  S++ +
Sbjct: 1948 QSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTL 2007

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             E E        +  P P + W ++   + P   + IH +G    L +     +D  ++ 
Sbjct: 2008 -EVE--------LTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFG 2058

Query: 563  C 563
            C
Sbjct: 2059 C 2059



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 36/138 (26%), Positives = 65/138 (47%), Gaps = 6/138 (4%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD- 1498
            V + PRFV + ++    +EG+   F C +E      ++  W+K+G  +T G++F+ + + 
Sbjct: 6104 VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 6160

Query: 1499 -FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLEQIQ 1556
              G + L I     ED G+Y C  VN +G+   S  L  +S           E  +  ++
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVE 6220

Query: 1557 VLEDRSKYHRTDMVDEVT 1574
            V E  +K  +  ++ E T
Sbjct: 6221 VTEQETKVPKKTVIIEET 6238



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 69/302 (22%), Positives = 120/302 (39%), Gaps = 39/302 (12%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT- 4570
            +P  FT   +N     G    L  +++   P++  W K  + ++   R  IL ++GT   
Sbjct: 3448 LPAKFTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCE 3504

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L I      D+G+Y CV     G+ R  A   +                  P   IE +K
Sbjct: 3505 LQICGLAMADAGEYLCVC----GQERTSATLTIRA---------------LPARFIEDVK 3545

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
            ++   EG      C++       V+W KG + ++    + + +   +  L+I      D 
Sbjct: 3546 NQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADT 3603

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G+Y CV     G+   +A L V    +A  +     LR+    EG  A  + ++ SK+ P
Sbjct: 3604 GEYSCV----CGQERTSAMLTV----RALPIKFTEGLRNEEATEGATAVLRCEL-SKMAP 3654

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             ++W +    + +     +  +G    L I     ED G + C      G+  TSA L V
Sbjct: 3655 -VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLC----MCGKERTSAMLTV 3709

Query: 4811 KS 4812
            ++
Sbjct: 3710 RA 3711



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 27/70 (38%), Positives = 40/70 (57%)

Query: 2004 VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            V +PT +V W  + +PV  G RF+   D     L IL     D+G Y+C+A NA+GEA  
Sbjct: 34   VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFA 93

Query: 2064 TSSVKVDAKS 2073
               ++VDA++
Sbjct: 94   AVGLQVDAEA 103



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 40/141 (28%), Positives = 67/141 (47%), Gaps = 6/141 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V   P+F   +     VEG +    C ++  G    ++ W+ +G  + TG++F+   E
Sbjct: 6102 ILVQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 1365 --FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL-EKI 1421
                 + L + +   ED G+Y C+  N+LG A  S  LR+ +      E  H   L   +
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAV 6219

Query: 1422 QYLE-DTSRYKKTDIIDESVT 1441
            +  E +T   KKT II+E++T
Sbjct: 6220 EVTEQETKVPKKTVIIEETIT 6240



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 4/78 (5%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEY 144
           G +A    ++ GNPTP VSW + + P+    ++ +    Q GD+  L I  +  GD G+Y
Sbjct: 24  GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA---QDGDLYRLTILDLALGDSGQY 80

Query: 145 TCTARNQYGEAICSVYIQ 162
            C ARN  GEA  +V +Q
Sbjct: 81  VCRARNAIGEAFAAVGLQ 98



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 40/164 (24%), Positives = 66/164 (40%), Gaps = 7/164 (4%)

Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           D   G   +F+C  T   +  V W+ +  ++       +  +    H L+   VT  D G
Sbjct: 808 DAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEG 866

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
             +C    + GE +   RL V E + V A + + R   L    G    L+       T  
Sbjct: 867 TYSC----RVGEDSVDFRLRVSEPKVVFAKEQLAR-RKLQAEAGASATLSCEVAQAQT-E 920

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           +TW KDG  +  + ++ +   G    L + +A  +DA  Y C A
Sbjct: 921 VTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 79/378 (20%), Positives = 148/378 (39%), Gaps = 33/378 (8%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GL 2699
            AP+F T L++ + + +G  V  +  V  +  P+++  WFK+G  L          D  G 
Sbjct: 5125 APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGG 5181

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE----DRHWLLGESLHPDSLDRIGA 2755
              L I ++   D G+Y C A N +G + + A ++++    D       +         G 
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 2756 LXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI-HFECNVEPSRDPTLKIEWFFNNK 2814
            L                    +  L ++    G  +  F+  V+    P  ++ WF + +
Sbjct: 5242 LSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGY--PAPRLYWFKDGQ 5299

Query: 2815 PLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFD 2874
            PL +    + T      +L+I     EDSG Y    +N+ G+A +S  L   G       
Sbjct: 5300 PLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG------- 5352

Query: 2875 TQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQ 2934
               P+ K   +  EQ    R+ +   P     +  K    I  + +   VEG+ +     
Sbjct: 5353 PDEPEEKPASDVHEQLVPPRMLERFTP-----KKVKKGSSITFSVK---VEGRPVPTVHW 5404

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            +  + + +  + W     +      + + S     +L L+DV  +  G YTC A N  G+
Sbjct: 5405 L--REEAERGVLW-----IGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457

Query: 2995 AFTSSTVYCTSKDNLIER 3012
            A  S++++ +    + E+
Sbjct: 5458 ALCSASLHVSGLPKVEEQ 5475



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 42/159 (26%), Positives = 68/159 (42%), Gaps = 9/159 (5%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +   EVTW+ + +++    + K+ V   G    L++     +++G  +
Sbjct: 1641 GASATLSCEVA-QAQTEVTWYKDGKKLSS--SSKVRVEAVGCTRRLVVQQAGQAEAGEYS 1697

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A    G      RL V E E  ++ +   R   L V+E E ++L A         +TW
Sbjct: 1698 CEA----GGQQLSFRLQVAELEPQISERPCRR-EPLVVKEHEDIILTATLATPSAATVTW 1752

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             KDGV I  +      + G   TL +  A+  D+A Y C
Sbjct: 1753 LKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC 1791



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 83/425 (19%), Positives = 158/425 (37%), Gaps = 53/425 (12%)

Query: 4380 RKITSTETTEIEH---KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            R+  ST T  +     K+++  R+V   +    P + T+ ++P    E +      +F  
Sbjct: 2439 RRTCSTMTGPVHFTVGKSRSSARLVVSDI----PVVLTRPLEPKTGRELQSVVLSCDFRP 2494

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
             P   ++WY+++ P+  S  F++      + L I ++   D+ V+   A    G+A  S 
Sbjct: 2495 AP-KAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSST 2549

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             + VE +     G +         Q+   T         +++  +  +V W  NG  +  
Sbjct: 2550 EVTVEAREVTVTGPL---------QDAEATEEGWASFSCELS-HEDEEVEWSLNGMPLYN 2599

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
            D  ++I  +   +TL++      D+G     ++  +  AR +                  
Sbjct: 2600 DSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVRV--------------- 2644

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
                 P   ++ L D    E   +   C+ V  P   V W K    + PS  +    TA 
Sbjct: 2645 ----KPVVFLKALDDLSAEERGTLALQCE-VSDPEAHVVWRKDGVQLGPSDKYDFLHTAG 2699

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L + +  PED G Y C      G     A+++V       ++     L+ + V EG+
Sbjct: 2700 TRGLVVHDVSPEDAGLYTC----HVGSEETRARVRVHDL----HVGITKRLKTMEVLEGE 2751

Query: 4737 PAQFKTQIT-SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG--TFTC 4793
               F+  ++         W   G  +  +  FQ   +G   +L++      D G   F+ 
Sbjct: 2752 SCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSV 2811

Query: 4794 RATTA 4798
            R  T+
Sbjct: 2812 RGLTS 2816



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 37/136 (27%), Positives = 64/136 (47%), Gaps = 8/136 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND--FGF 3614
            PP F          E   A F C +       +R  W+ +G  L TG++ +T+++   G 
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
            ++L I    + D GLY C+  NR G A  S +L++   Q  +L+ Q   H +    +++ 
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLVAAVEV 6221

Query: 3675 LE-ETLHKREEITIED 3689
             E ET   ++ + IE+
Sbjct: 6222 TEQETKVPKKTVIIEE 6237



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            P+ +  P F T  K  + +  G  A    ++  +G+ T +V W KD +PV A +R     
Sbjct: 4    PQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQ 60

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            +     LTI  + + D+G Y CRA NAIG+A  +  L +  +     ++ H
Sbjct: 61   DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 111/485 (22%), Positives = 188/485 (38%), Gaps = 51/485 (10%)

Query: 922  KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
            +EGG A F+  + P   S + V W +DG  ++ S +     +    +LTI  + + DAG 
Sbjct: 1911 EEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ 1967

Query: 982  YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
             T  A  A    ++SA L +     +  +   P  +E+   +      + R   E++ T+
Sbjct: 1968 ITVEAEGA----SSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTR 2022

Query: 1042 KPRFLGPLKGTNKIVEG-------QSAHFEAR----VEPQSDLT---MTVEWYFNGKQIT 1087
                L P K      EG        +  F  R     E   D T   +TVE     +Q+ 
Sbjct: 2023 NATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM----RQVR 2078

Query: 1088 SANRIQTYH--DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSS 1145
                +Q     + G   +++    A+  G +T   R+     Q   +  +  R  + T +
Sbjct: 2079 LVRGLQAVEAREQGTATMEVQLSHADVDGSWT---RDGL-RFQQGPTCHLAVRGPMHTLT 2134

Query: 1146 IHRGLYEKTRHIEESKFVEPMYQIEEISKSKPV-FVQPLSNPPPVSEGKNIHLECRLEPM 1204
            +  GL  +   +   K          +    PV F +PL +    +E + + LEC L   
Sbjct: 2135 LS-GLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVV-TTEKEKVTLECELSR- 2191

Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264
              P + V W  +G  +  G            +L I     AD G Y   A  H   A +S
Sbjct: 2192 --PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDA--H--DAQSS 2245

Query: 1265 AIVRVIERS-DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP-QFSRALHNIET 1322
            A V+V  R+  ++      +   +IQ + + A    Q+R    V + P    R L +   
Sbjct: 2246 ASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLR----VKELPVTLVRPLRDKIA 2301

Query: 1323 VEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGV 1382
            +E     LEC+   V   + +V WF   + ++ G ++    +  Y  L +  V+ ED   
Sbjct: 2302 MEKHRGVLECQ---VSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDT 2358

Query: 1383 YTCQA 1387
            YTC A
Sbjct: 2359 YTCDA 2363



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--H 4460
            G +    PP F  K++     E E A+F    +G P P I+WY++   +     FQ    
Sbjct: 6100 GKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              S   +L+IR    ED  ++     NR G+A+ SA L ++    Q +
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQ 6207



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 763 EEQTSQRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           + Q S  P+F+ RP   +  +  G++A    Q+  V +PT +V W KD +P+ A +R   
Sbjct: 3   QPQFSGAPRFLTRPKAFV--VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRL 58

Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
             +     L I+ L   D+G Y  RA N +GEA +   ++V A +
Sbjct: 59  AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEA 103



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 5/98 (5%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FG 3338
            PP+F+ +++  +  VEG+ A F   +     P ++  W+ +G  L  G++++T  +   G
Sbjct: 6107 PPRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 6163

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
            +++L I    +E+ G YEC   N+LG     A L+  S
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND--FG 3751
            PPRF  +++ +  V EG    F C +E  G P  +I W+ +G    TG++  TL++   G
Sbjct: 6107 PPRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 6163

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + L I      D G Y C   N+ GSA  +A++
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAEL 6197



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 88/408 (21%), Positives = 146/408 (35%), Gaps = 57/408 (13%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++P  F + ++   V E   A           P +KW   N  ++    + +        
Sbjct: 3182 ARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLE 3240

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L++R +  +DS  ++       G    SA L V           +P  F    +N   T 
Sbjct: 3241 LVVRNLRPQDSGRYSCSF----GDQTTSATLTVTA---------LPAQFIGKLRNKEATE 3287

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ-DSGKYEC 4586
            G    L  +++   P++  W K G +   D     L +DG    L +      D+ +Y C
Sbjct: 3288 GATATLRCELSKAAPVE--WRK-GSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC 3344

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            V     GE R  A   +         +P       P   I  L+ +   EG      C++
Sbjct: 3345 VC----GEERTSASLTI---------RPM------PAHFIGRLRHQESIEGATATLRCEL 3385

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
              K  P V+W KG + ++      + +      L+I      D G+Y CV        T+
Sbjct: 3386 -SKAAP-VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATL 3443

Query: 4707 AAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
              K           LPA     LR+    EG  A    ++ SK+ P ++W +    + + 
Sbjct: 3444 TVKA----------LPAKFTEGLRNEEAVEGATAMLWCEL-SKVAP-VEWRKGPENLRDG 3491

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  EG    L I      D G + C      GQ  TSA L +++
Sbjct: 3492 DRYILRQEGTRCELQICGLAMADAGEYLC----VCGQERTSATLTIRA 3535



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 2/104 (1%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F+   K+     G       +I  VG+PT ++ W K+ Q + A +RF          L
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRL 67

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQH 740
            +L L + DSG+Y CRA +A G A     L V   A     + H
Sbjct: 68  TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 2/81 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            VS GK+  L C++  +G+PT +V W  + + V  G+RF+   D     L I+     D+G
Sbjct: 21   VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSG 78

Query: 1249 EYTVRAVNHLGSAHTSAIVRV 1269
            +Y  RA N +G A  +  ++V
Sbjct: 79   QYVCRARNAIGEAFAAVGLQV 99



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 57/230 (24%), Positives = 91/230 (39%), Gaps = 19/230 (8%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL--PSGTRYKSTHDFSYVSL 2833
            F+    +I  +EG    F C V  S  P   + W  + + L  P G R +        +L
Sbjct: 112  FLLRPTSIRVREGSEATFRCRVGGSPRPA--VSWSKDGRRLGEPDGPRVRVEELGEASAL 169

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             I      D G Y  +A N  G+A+ + +L    D             A L  +++  EA
Sbjct: 170  RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
              A+G   S P T                + EG+   L   V    +P  +  W  +G++
Sbjct: 230  MRAEGAPASPPSTG----------TRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQL 277

Query: 2954 LEQGSRFKLTSDF--GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + +G R  +  D    FV L ++   + D G+YTC A N  G+ ++S  V
Sbjct: 278  VTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 58/224 (25%), Positives = 95/224 (42%), Gaps = 20/224 (8%)

Query: 2242 PRFVTELRGTT-HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL--QSAARFHITFDFG 2298
            P F+  LR T+  V EG  A F C+V     P   + +  +G+ L      R  +  + G
Sbjct: 110  PHFL--LRPTSIRVREGSEATFRCRVGG--SPRPAVSWSKDGRRLGEPDGPRVRVE-ELG 164

Query: 2299 YVS-LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELE 2357
              S L I+   P D G Y V+A N LG  ++A ++ V +  +  +          +  L+
Sbjct: 165  EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ 224

Query: 2358 SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK 2417
                  R E   P +   P  T        + EG+ A   C +   G+P  +  W ++ +
Sbjct: 225  RRREAMRAE-GAPAS---PPSTG--TRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQ 276

Query: 2418 LIEDSSRITKTHDF--GYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            L+ +  R     D    +V + I   +  D G+Y C ASNL+G+
Sbjct: 277  LVTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQ 319



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 93/458 (20%), Positives = 173/458 (37%), Gaps = 54/458 (11%)

Query: 4362 VAKQKQTQKEVVG--DKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK--KM 4417
            ++   + + E VG   + + ++    E  E   +A  Q+      V   +P I  +  + 
Sbjct: 1666 LSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAELEPQISERPCRR 1725

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477
            +P  V EHE               + W ++   I+ S   +  +      L +    V D
Sbjct: 1726 EPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLD 1785

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            SA+++     R G       + VEE         V   F    + V    G  V L  ++
Sbjct: 1786 SAIYSC----RVGAEGQDFPVQVEE---------VAAKFCRLLEPVCGELGGTVTLACEL 1832

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
            +     +V W     +++   R +++ E    +L +L    +D+G+Y C     + +   
Sbjct: 1833 SPACA-EVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVC----ESRDDHT 1887

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             A+  VS+P                 + +  L   +  EG    F C +V      V W+
Sbjct: 1888 SAQLTVSVPRVV--------------KFMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWF 1932

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            +   L++PS+ F +S++   ++L IS+   ED G     A  ++     +A L+V +   
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASS----SAALRVRE--- 1985

Query: 4718 ADNLPAL--TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                P L    L    V E      + ++T +  P ++W R    +    + ++  EG  
Sbjct: 1986 ---APVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGAR 2041

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              L++ N    D G F C         +T AKL V+ +
Sbjct: 2042 HRLVLHNVGFADRGFFGCETP----DDKTQAKLTVEMR 2075



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 13/212 (6%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P  F  PL+ V   E  K+  E  +     P + + WLK+G  + A        +    S
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACRS 2221

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L +      D G Y C A  A   A  K V   T      R     E    IQ + + ++
Sbjct: 2222 LTIYRCEFADQGVYVCDAHDAQSSASVK-VQGRTYTLIYRRVL--AEDAGEIQFVAENAE 2278

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
             + Q  ++E        +RPL+D   +++ R    E Q   VS  + +V W+K  + +  
Sbjct: 2279 SRAQLRVKELP---VTLVRPLRDKIAMEKHRGV-LECQ---VSRASAQVRWFKGSQELQP 2331

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
              +   + +  Y  L I  + AED  +YT  A
Sbjct: 2332 GPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 10/161 (6%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +P  EVTW+ + +++    + K+ +   G    L++  V  +D+G  +
Sbjct: 1181 GTTAMLSCEVA-QPQTEVTWYKDGKKLSS--SSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A  +    +FQ  L++ E + V A + +   + +    G    L+       T  +TW
Sbjct: 1238 CEAGGQ--RVSFQ--LHITEPKAVFAKEQLVH-NEVRTEAGASATLSCEVAQAQT-EVTW 1291

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             KDG  +  + ++RI   G    L + +A  +DA  Y C A
Sbjct: 1292 YKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 8/137 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FG 2298
            PPRFV ++R +  V EG+ A F C +E    P +R  +Y +G  L +  +F    +   G
Sbjct: 6107 PPRFVNKVRASPFV-EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 6163

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL---EKIRE 2355
             + L I+    ED G Y  + +N LG   ++  + + +      E    E L    ++ E
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 6223

Query: 2356 LESAEPFKRPEIPEPVT 2372
             E+  P K   I E +T
Sbjct: 6224 QETKVPKKTVIIEETIT 6240



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 51/200 (25%), Positives = 75/200 (37%), Gaps = 14/200 (7%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR-FTPIYDF 4028
            +Q P F+ +  S       E T F C++   G P   V W  +G+ L   +     + + 
Sbjct: 107  EQAPHFLLRPTSIRVREGSEAT-FRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 4029 GYV-AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKI 4087
            G   A+      P D G Y  RA N  G     A +       +V         +     
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAAL-------VVDSDAADTASRPGTST 216

Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
              + A  Q   E +  E     PP   +     TV EG+ AR  C VTG PKP  +W  +
Sbjct: 217  AALLAHLQRRREAMRAEGAPASPPSTGTR--TCTVTEGKHARLSCYVTGEPKPETVWKKD 274

Query: 4148 GNTIVNGSRYKLTYDGMYHF 4167
            G  +  G R+ +  D   +F
Sbjct: 275  GQLVTEGRRHVVYEDAQENF 294



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 76/280 (27%), Positives = 111/280 (39%), Gaps = 31/280 (11%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKA--GSRFRTFCDF 3475
            +AP F +  ++I  +REG  A F  R+  +  P   V W  +G+ L    G R R     
Sbjct: 108  QAPHFLLRPTSIR-VREGSEATFRCRVGGSPRP--AVSWSKDGRRLGEPDGPRVRVEELG 164

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKI 3535
                L I    P D G Y  RA N  G A   A++ V        ++       GT    
Sbjct: 165  EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS------DAADTASRPGT-STA 217

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A L       + +  E    +PP  +T      ++E   A   C +    +      W  
Sbjct: 218  ALLAHLQRRREAMRAEGAPASPP--STGTRTCTVTEGKHARLSCYV--TGEPKPETVWKK 273

Query: 3596 NGKPLLTGSRVKTINDFGF-VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQG 3654
            +G+ +  G R     D     +L+I    Q D GLYTC A+N  G+ T S  L V     
Sbjct: 274  DGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-TYSSVLVV----- 327

Query: 3655 IILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNP 3694
             + EP +P  FK   + +Q LE  + ++E  T   E P P
Sbjct: 328  -VREPAVP--FK---KRLQDLE--VREKESATFLCEVPQP 359



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 67/288 (23%), Positives = 114/288 (39%), Gaps = 24/288 (8%)

Query: 2941 PDLKIEWYFNGKVLEQ--GSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P   + W  +G+ L +  G R ++        L +     RD G Y  +A N  G A  +
Sbjct: 137  PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
            + +   S  +  +    P GT     + +L+   R+    + +     PP   T      
Sbjct: 197  AALVVDS--DAADTASRP-GTSTAALLAHLQ---RRREAMRAEGAPASPPSTGT---RTC 247

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTT 3116
             ++EG+  H   S   TG+      W  +G+ +    R   VY  A    VL+IL  K +
Sbjct: 248  TVTEGK--HARLSCYVTGEPKPETVWKKDGQLVTEGRR-HVVYEDAQENFVLKILFCKQS 304

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G Y+C A+N  GQ   SV +   + +   K R    +Q++E +++ +SA F C    V
Sbjct: 305  DRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKR----LQDLE-VREKESATFLC---EV 356

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              P  +  W+     +  S +     +     L +      D   Y+C
Sbjct: 357  PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC 404



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 5/137 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--R 690
            V  PP+F+  +++   +EG    F   IE  G P  +I W K+G  +   ++F ++   R
Sbjct: 6104 VQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPR 6161

Query: 691  FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQHPETLQYIQQ 749
             G + L + + + +D G Y C  V+  G A   A L + +P    +      + +  ++ 
Sbjct: 6162 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEV 6221

Query: 750  LEDYSKYQHQESIEEQT 766
             E  +K   +  I E+T
Sbjct: 6222 TEQETKVPKKTVIIEET 6238



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 3/95 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F T  K++   V G+   L  Q+     P  ++ W K+   +  GAR +   D  L 
Sbjct: 9    APRFLTRPKAFVVSV-GKDATLSCQIVGNPTP--QVSWEKDQQPVAAGARFRLAQDGDLY 65

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             L+I  L   DSG Y C+A N +GEA +   ++++
Sbjct: 66   RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 73/320 (22%), Positives = 126/320 (39%), Gaps = 35/320 (10%)

Query: 2993 GEAFTSSTVY---CTSKDNLIERTQHPKGTEG--LEKIQN-LEDSLRKEPGQQPDDDTGR 3046
            G+A  +S+VY   C    + +   + P    G  L+ + N +E S+R E    P     +
Sbjct: 648  GQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANK 707

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPT-GDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP      ++++        H EA L+    DQ+  + W  +G+T+    +     + G 
Sbjct: 708  PP--AAAAREVL-----ARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGR 760

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
             VL +      D+G Y C   ++ G+    + ++ + +    K    + +  +     G 
Sbjct: 761  RVLLVRDVARDDAGLYEC--VSRGGRIAYQLSVQGLARFL-HKDMAGSCVDAVA----GG 813

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYT-QNHDSGEYVC 3224
             A FEC      +  + + WY +G  + HS       D G     +A T    D G Y C
Sbjct: 814  PAQFEC---ETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            R     GED     +       V+ +    + LA+ R+L++  GA   T S   A+    
Sbjct: 871  RV----GEDSVDFRLRVSEPKVVFAK----EQLAR-RKLQAEAGA-SATLSCEVAQAQTE 920

Query: 3285 ITQIQDVTKLVEGQSAHFEA 3304
            +T  +D  KL        EA
Sbjct: 921  VTWYKDGKKLSSSSKVCMEA 940



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 12/163 (7%)

Query: 1701 SAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            S   +++ Q P  F   ++     E + A F   +   G P  ++ W ++G  +   N+ 
Sbjct: 6097 STLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKF 6154

Query: 1760 TTMHD--FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH-ES 1816
             T+ +   G + L ++  + ED G Y C  +N LG A  S+ L +QS      E  H E 
Sbjct: 6155 QTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQ 6214

Query: 1817 ALQKIQQLEDSSRYQRR----EDVEVAVNQAPRFITQLNGPTK 1855
             +  ++  E  ++  ++    E+    V ++PR   Q   P+K
Sbjct: 6215 LVAAVEVTEQETKVPKKTVIIEETITTVVKSPR--GQRRSPSK 6255



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 50/198 (25%), Positives = 77/198 (38%), Gaps = 9/198 (4%)

Query: 2007 PTMRVEWYCNGRPVQQ--GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            P   V W  +GR + +  G R +        AL I  A   D GTY  +A N +G A   
Sbjct: 137  PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196

Query: 2065 SSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEG 2124
            +++ VD+ +              +  L++  R     E  P   P   +  T    + EG
Sbjct: 197  AALVVDSDAADTASRPGTSTAALLAHLQR-RREAMRAEGAPASPP---STGTRTCTVTEG 252

Query: 2125 DRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY-VALDILYTYAEDSGTYM 2183
              A   C V    +P     W  +GQ +  G R+    D      L IL+    D G Y 
Sbjct: 253  KHARLSCYVT--GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYT 310

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C A+N +G+  ++  + V
Sbjct: 311  CTASNLVGQTYSSVLVVV 328



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 4/147 (2%)

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
            D+ T    + ++++  +   AA +  +VR+++   + P FS    + E   G  + LEC 
Sbjct: 4861 DLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECV 4920

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTG-HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            +    D  +R  W  +G  +  G H           +L +  +   D+G YTCQ +N+ G
Sbjct: 4921 VASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFG 4978

Query: 1393 EAVTSCALRVIAKKDLILESQHPSGLE 1419
            + VT  A  V++  +   ES     L+
Sbjct: 4979 Q-VTHSACVVVSGSESEAESSSGGELD 5004



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            +++ Q    P FLT   +   +  G  A   C++  + +P   + W  + Q + AG R+R
Sbjct: 1    MDQPQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFR 57

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               D     L IL     DSG Y+C+A N +GEA     L+V
Sbjct: 58   LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 58/269 (21%), Positives = 102/269 (37%), Gaps = 33/269 (12%)

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  V W K+   + P  + K+  E     L IL   P D+G Y C     AG A    E 
Sbjct: 2496 PKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC----QAGSAHSSTEV 2551

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V                     +  PL+D    E     FSC++  +    V+W     
Sbjct: 2552 TVEAREV---------------TVTGPLQDAEATEEGWASFSCELSHED-EEVEWSLNGM 2595

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +    + ++S     +TL +      D G    +   S+ +V+ +A+L+V    +   +
Sbjct: 2596 PLYNDSFHEISHKGRRHTLVLKSIQRADAG----IVRASSLKVSTSARLEV----RVKPV 2647

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L  L D+   E      + ++ S  +  + W ++G  +  +  +  +H      L++ 
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVH 2706

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED G +TC      G  ET A++ V
Sbjct: 2707 DVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 15/187 (8%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F++  Q ++V EG      C ++ R    V W     Q+     ++ +V +     L++
Sbjct: 3980 RFLRELQHQEVDEGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQ-MVQDGAAAELLV 4037

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
              V   D+G  TC     +G T     L+V    +V  PKF  R  +L    G+   L  
Sbjct: 4038 RGVEQEDAGDYTC----DTGHTQSMASLSV----RVPRPKFKTRLQSLEQETGDIARLCC 4089

Query: 513  RAVGTPTPRIT-WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +     +  +  W K+GV +   P+  + + G    L I + +A D   Y C    V G 
Sbjct: 4090 QLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC----VTGG 4145

Query: 572  TATRARL 578
              T A L
Sbjct: 4146 QKTAASL 4152



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 8/101 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL------VECNKYSMRYNE 124
            PP   + F   +  +G +  F  K+ G P P V W R++A         +   Y++  + 
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
            Q    SL++  +G   +G YTC A N  G+A+CS  +   G
Sbjct: 5430 QQH--SLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSG 5468



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 64/239 (26%), Positives = 88/239 (36%), Gaps = 22/239 (9%)

Query: 768  QRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI-TASSRITSIFNF 825
            Q P F+ RP      ++EG  A F  ++     P   V W KDGR +         +   
Sbjct: 108  QAPHFLLRPTSI--RVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 826  GYVS-LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKT 884
            G  S L I   R  D G+Y VRA N LG A + A++ V + +  TA       R      
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTAS------RPGTSTA 217

Query: 885  XXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVE 944
                              P S      +T      ++ EG  A     +   G+      
Sbjct: 218  ALLAHLQRRREAMRAEGAPASPPSTGTRT-----CTVTEGKHARLSCYVT--GEPKPETV 270

Query: 945  WLKDGRPVEASSRITTFFNFGY-VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG+ V    R   + +      L I      D G YTC A N +GQ T S+ L +V
Sbjct: 271  WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-TYSSVLVVV 328



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 3/90 (3%)

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            SA+ EV  +  VF   + D+   E      +     V DP+  V W ++GV +  S++  
Sbjct: 2637 SARLEVRVKPVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYD 2693

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
             +H  G   L +  V+PED+G YTC   +E
Sbjct: 2694 FLHTAGTRGLVVHDVSPEDAGLYTCHVGSE 2723



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSG 3491
            EGE+A F   +     P ++  WY +G  L  G++F+T  +   G ++L I     ED G
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 3492 EYLCRAYNNYGEAVTTASMKVQ 3513
             Y C   N  G A  +A +++Q
Sbjct: 6179 LYECELVNRLGSARASAELRIQ 6200



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 54/215 (25%), Positives = 87/215 (40%), Gaps = 12/215 (5%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            VT  P   +RP       E + V  EC+L   +  N+ V W K+G  +  G         
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQG 2217

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559
               +L I      D G+Y C A +       S ++  R+ T I R    E   E IQ + 
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHD--AQSSASVKVQGRTYTLIYRRVLAEDAGE-IQFVA 2274

Query: 1560 DRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKP 1619
            + ++      V E+    P+  T ++ +  K     H       VS A+ +V W+  ++ 
Sbjct: 2275 ENAESRAQLRVKEL----PV--TLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQE 2328

Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
            L+ G ++   ++  +  L I     ED  TYTC A
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 56/237 (23%), Positives = 95/237 (40%), Gaps = 21/237 (8%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++V  E + +  EC  E SR P + + W  +   L +G         +  SL I
Sbjct: 2168 FSRPLQDVVTTEKEKVTLEC--ELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                  D G+Y C A +++ SA+     R      + +     +    ++ V +  E+R 
Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQGRTY---TLIYRRVLAEDAGEIQFVAENAESR- 2280

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLE 2955
            A+ R   +P T        I +     ++E QV     QV           W+   + L+
Sbjct: 2281 AQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVR----------WFKGSQELQ 2330

Query: 2956 QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
             G +++L SD  +  L + DV+  D   YTC A    G+  TS+  +   +   I R
Sbjct: 2331 PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEEQSITIVR 2383



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ +   PRF+  ++ +   VEG+ A F   +E        + WY +G  +T+ N+ QT 
Sbjct: 6101 KILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAP--YPQIRWYKDGALLTTGNKFQTL 6157

Query: 1096 HD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             +   G + L I +   ED G+Y     N  G A+ SA + +++         HR
Sbjct: 6158 SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 6212



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/112 (26%), Positives = 57/112 (50%), Gaps = 4/112 (3%)

Query: 2234 VEEPKIS-PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292
            +++P+ S  PRF+T  +    V  GK A   CQ+  V +P  ++ +  + + + + ARF 
Sbjct: 1    MDQPQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFR 57

Query: 2293 ITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344
            +  D     L I      D+G+Y  +A NA+G   +A+ + V A+ +   ++
Sbjct: 58   LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA 109



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            PRF    K  + V  G      C++  VG+PT ++ W  + +P A G+R     D     
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            L I  +   D+G+Y CRA N  G A     +   A+
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 18/195 (9%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            ++ +AL  +F++  ++++  EG      C ++ +  P V W      +R    + +   +
Sbjct: 3795 LTVRALPARFIEDVKNQEAREGATAVLQCELS-KAAP-VEWRKGSETLRGGDRYSL--RQ 3850

Query: 445  SGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
             G    L I  ++++D+G  +CV     G+      L V    +   P F E   +L   
Sbjct: 3851 DGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTV----RAPQPVFREPLQSLQAE 3902

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            EG    L    +  PT  + W K G+ +  N        G  + L +   +  D   Y C
Sbjct: 3903 EGSTATLQCE-LSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC 3961

Query: 564  TAQNVAGSTATRARL 578
            T     GS AT A L
Sbjct: 3962 T----CGSQATSATL 3972



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/92 (28%), Positives = 43/92 (46%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F    + + F +G +A+F   + G P P + W +  A L   NK+      ++G + 
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 6166

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            L+I+     D G Y C   N+ G A  S  ++
Sbjct: 6167 LVIRAASKEDLGLYECELVNRLGSARASAELR 6198



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSG 2180
            EG+ A F C +E    P+  I W+ +G  +  G++++T  +   G + L I     ED G
Sbjct: 6121 EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
             Y C+  N+LG A  +  L++
Sbjct: 6179 LYECELVNRLGSARASAELRI 6199



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F    K   V+  + A    ++  VG+P  +V W ++  P+ A  R     D     
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814
            L +  +   DSG Y CRA N +GEA  +  L V ++A+   ++ H
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 56/218 (25%), Positives = 79/218 (36%), Gaps = 13/218 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKM--GSRFRTTHDFGFVTLDINSVVANDAG 2579
            EG  A +  RV   G P     W  +G  L    G R R         L I +    D G
Sbjct: 123  EGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG 180

Query: 2580 LYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQ 2639
             Y  +A N  G                 D A RP +     L  A + +  E     G  
Sbjct: 181  TYEVRAENPLGAASAAAALVVDSDAA--DTASRPGTSTAALL--AHLQRRREAMRAEGAP 236

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
             +P  T        + EG+H  L   V    +P  +  W K+G  +T G R     D   
Sbjct: 237  ASPPSTGTRTC--TVTEGKHARLSCYVTG--EPKPETVWKKDGQLVTEGRRHVVYEDAQE 292

Query: 2700 -VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               L I   +  D G+YTC A+NL+G+  S+  + + +
Sbjct: 293  NFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 58/217 (26%), Positives = 97/217 (44%), Gaps = 28/217 (12%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA---NL 999
            V WLKDG  + A   +         +LTI      D G Y C A++A   A+        
Sbjct: 2196 VRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTY 2255

Query: 1000 TIVTKKDIIAESQHPGGLEKIQYL-EDASRYSKRTEEEVKITQKPRFLGPLKGTNKI-VE 1057
            T++ ++ ++AE        +IQ++ E+A   ++   +E+ +T     + PL+  +KI +E
Sbjct: 2256 TLIYRR-VLAED-----AGEIQFVAENAESRAQLRVKELPVT----LVRPLR--DKIAME 2303

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
                  E +V   S  +  V W+   +++    + +   D  Y  L I+ V AED   YT
Sbjct: 2304 KHRGVLECQV---SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYT 2360

Query: 1118 VVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKT 1154
                  AG+ + SA   VE +S     +I RGL + T
Sbjct: 2361 C----DAGDVKTSAQFFVEEQS----ITIVRGLQDVT 2389



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP   T  K   +  G+ A    ++  V + T +V W  + +P+ +G+RF    +     
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEA 1661
            L I+     DSG Y CRA NA+GEA
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEA 91



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 43/198 (21%), Positives = 81/198 (40%), Gaps = 11/198 (5%)

Query: 370  YITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            Y  + + +    R+ I+E K +  +   V  +     G      C V  +   EVTW+ +
Sbjct: 1052 YSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVA-QAQTEVTWYKD 1110

Query: 429  DRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
             +++    + K+ +   G    L++     +D+G  +C A    G       L++ E + 
Sbjct: 1111 GKKLSS--SSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA----GGQRVSFHLHITEPKG 1164

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
            V A K     + +    G   +L+   V  P   +TW KDG  +  + ++R+   G    
Sbjct: 1165 VFA-KEQSVHNEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRR 1222

Query: 548  LDIPRAKASDAAWYQCTA 565
            L + +   +DA  Y C A
Sbjct: 1223 LVVQQVGKADAGEYSCEA 1240



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 41/199 (20%), Positives = 81/199 (40%), Gaps = 11/199 (5%)

Query: 369  QYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            +Y  +   +     + ++E KA+  +     ++     G      C V  +   EVTW+ 
Sbjct: 1511 EYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTEVTWYK 1569

Query: 428  NDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
            + +++    + K+ +   G    L++     +D+G  +C    K+G+      L+V E +
Sbjct: 1570 DGKKLSS--SSKVRMEAVGCTRRLVVQEAGQADAGEYSC----KAGDQRLSFHLHVAEPK 1623

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
             V A K       +    G    L+       T  +TW KDG  +  + ++R+   G   
Sbjct: 1624 VVFA-KEQPAHREVQAEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRVEAVGCTR 1681

Query: 547  TLDIPRAKASDAAWYQCTA 565
             L + +A  ++A  Y C A
Sbjct: 1682 RLVVQQAGQAEAGEYSCEA 1700



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 55/235 (23%), Positives = 98/235 (41%), Gaps = 15/235 (6%)

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            L   P   +V+ G       ++ + +D+ + Y  D    +T  +  + E+++    V+  
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDT-YTCDAGDVKTSAQFFVEEQSIT--IVRGL 2385

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            QD  V E     F+C  +        W +    ++   N   L  E   H LM+     +
Sbjct: 2386 QDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVG-LEQEGTVHRLMLRRTCST 2444

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
             +G V        G++    RL V+    VV  + +E  +    RE + VVL+      P
Sbjct: 2445 MTGPVHFTV----GKSRSSARL-VVSDIPVVLTRPLEPKTG---RELQSVVLSCDF--RP 2494

Query: 519  TPR-ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P+ + W KD  P+ P+ + ++  +G  + L I R   +DA  Y+C A +   ST
Sbjct: 2495 APKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSST 2549



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-F 691
            V+ PP F   L   TA  G  +    R+   G P   I W K+G++++       I    
Sbjct: 6010 VWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPD 6067

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
            G  +L + SL   DSG+Y C A SA G   T  K ++ V PR
Sbjct: 6068 GSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPR 6109



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P F++ P A  V  G+ A   C++ G+P P+V W  +   +  G+R++L  DG +Y   I
Sbjct: 10   PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 4170 PKTRQYDTGK 4179
                  D+G+
Sbjct: 70   LDLALGDSGQ 79



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 54/238 (22%), Positives = 94/238 (39%), Gaps = 23/238 (9%)

Query: 1573 VTTQAPIC-TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631
            V T+ P+  +  L++V   E ++   E  L   S   + V W  +   L++G        
Sbjct: 2160 VVTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQ 2216

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691
                +L I  C   D G Y C A +A             S  S+ ++ +    + R    
Sbjct: 2217 GACRSLTIYRCEFADQGVYVCDAHDA------------QSSASVKVQGRTYTLIYRRVLA 2264

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLI---PVGDPKLRVEWLR 1748
            ED  + Q  +   E   Q  V  +P+  +R   ++ A  + R +    V     +V W +
Sbjct: 2265 EDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFK 2324

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
                ++   +   + D  Y  L +  V+ ED  TYTC A    G+  TS+  FV+ ++
Sbjct: 2325 GSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEEQS 2378



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/350 (21%), Positives = 129/350 (36%), Gaps = 24/350 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P  +TRP   +   E Q V   C   P   +   V+W+K+  P++   +F+   +     
Sbjct: 2468 PVVLTRPLEPKTGRELQSVVLSCDFRPAPKA---VQWYKDDTPLSPSEKFKMSLEGQMAE 2524

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L I+ L+  D+G+Y C+A +   + EV+  +  R  T +    Q+    E+         
Sbjct: 2525 LRILRLMPADAGVYRCQAGSAHSSTEVT--VEAREVT-VTGPLQDAEATEEGWASFSCEL 2581

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
             H  + V+      P+   S   +  K G+R     + I  +DA   +    + K   S 
Sbjct: 2582 SHEDEEVEWSLNGMPLYNDSFHEISHK-GRRHTLVLKSIQRADA--GIVRASSLKVSTSA 2638

Query: 1624 SRFTETNNFGFV-ALDIMSCLPEDSGTYTCRAINALGEAV--TSGIAIVHSKKSIYLESQ 1680
                      F+ ALD +S     +    C   +     V    G+ +  S K  +L + 
Sbjct: 2639 RLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTA 2698

Query: 1681 -HEGALPRLNQLEDTSKYQRHSAQDEVITQAPV------FTMPMKDIRVAENQAAHFEAR 1733
               G +      ED   Y  H   +E   +  V       T  +K + V E ++  FE  
Sbjct: 2699 GTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECV 2758

Query: 1734 LI--PVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSG 1781
            L      DP +   W   G  + +S+R           L ++   P D+G
Sbjct: 2759 LSHESASDPAM---WTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG 2805



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F    +N     G    F+  + G P P V W  K   L+E + + M   +Q G   L
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWF-KDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 132  LIKQIGPGDEGEYTCTARNQYG 153
            +I  + P D G Y C A N  G
Sbjct: 5185 IITAVVPADMGVYRCLAENSMG 5206



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 98/470 (20%), Positives = 184/470 (39%), Gaps = 65/470 (13%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            V+W +    L   +K  M     T    L++ Q G  D GEY+C A  Q       +  +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTR--RLVLPQAGKADAGEYSCEAGGQRVSFHLHI-TE 1161

Query: 163  PEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR-QTQKVAYTNGTDHSSTDDF 221
            P+G              + V   V+ +A  T   + E ++ QT+   Y +G   SS+   
Sbjct: 1162 PKGVFAKE---------QSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKV 1212

Query: 222  KVDTFEYRLLREVSFRESITKRYVGESDVQISTE-IDRSLGPVSPPKIAQKPR----NSK 276
            +++       R +  ++ + K   GE   +   + +   L    P  +  K +      +
Sbjct: 1213 RMEV--KGCTRRLVVQQ-VGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVR 1269

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             + GA A    +++   +  VTW+K+G++L +S+K  I        L V+   ++D+G Y
Sbjct: 1270 TEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T  A    G    S +L V  P   + ++Q +             +++    A+A    +
Sbjct: 1329 TCEA----GGQRLSFHLDVSEPKAVFAKEQLA-----------HRKVQAEAGAIATLSCE 1373

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNV 455
            V Q +  TE                 VTW+ + +++    + K+ +   G    L++   
Sbjct: 1374 VAQAQ--TE-----------------VTWYKDGKKLSS--SSKVRMEAVGCTRRLVVQQA 1412

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
              +D+G  +C    ++G       L+V E  +VV  K       +  + G    L+    
Sbjct: 1413 CQADTGEYSC----EAGGQRLSFSLDVAE-PKVVFAKEQPVHREVQAQAGASTTLSCEVA 1467

Query: 516  GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
               T  + W KDG  +  + ++R+   G    L + +A  + A  Y C A
Sbjct: 1468 QAQT-EVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA 1516



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 113/481 (23%), Positives = 190/481 (39%), Gaps = 51/481 (10%)

Query: 1998 EATLTPVNDPT-MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
            EAT   V  P+ + V W+ +G  +Q   +F  +      +L I     ED G    +A  
Sbjct: 1915 EATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG 1974

Query: 2057 AVGEA-VTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKP-------IEEEQPGQR 2108
            A   A +      V  K  L   T++E R     E+E   RP P            PG+ 
Sbjct: 1975 ASSSAALRVREAPVLFKKKLEPQTVEE-RSSVTLEVE-LTRPWPELRWTRNATALAPGKN 2032

Query: 2109 PVFLTALTS-----LENLKEGDRAHFECRV-EPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
             V + A  +     L N+   DR  F C   +      LT++      ++  G +     
Sbjct: 2033 -VEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM--RQVRLVRGLQAVEAR 2089

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII-LDTQHP--NGLEK 2219
            + G   +++  ++A+  G++         +   TC L V G  + + L    P  +GL  
Sbjct: 2090 EQGTATMEVQLSHADVDGSWTRDGLRF--QQGPTCHLAVRGPMHTLTLSGLRPEDSGL-M 2146

Query: 2220 IRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
            + + E    S R+ V E  +S  R + ++  T    E +    EC++     PN+ + + 
Sbjct: 2147 VFKAEGVHTSARLVVTELPVSFSRPLQDVVTT----EKEKVTLECELSR---PNVDVRWL 2199

Query: 2280 HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKG- 2338
             +G  L++     I       SL I  C   D G Y   A +A     S+ S+ V  +  
Sbjct: 2200 KDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTY 2255

Query: 2339 SIISESQRPEGLEKIREL-ESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNI-QEGQTAH 2395
            ++I      E   +I+ + E+AE   +  + E PVT  RP+        D I  E     
Sbjct: 2256 TLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLR-------DKIAMEKHRGV 2308

Query: 2396 FDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
             +C+   V   + +V WF+  + ++   +     D  Y  + IS V  EDE  Y C A +
Sbjct: 2309 LECQ---VSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD 2365

Query: 2456 L 2456
            +
Sbjct: 2366 V 2366



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 8/109 (7%)

Query: 635  PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            P P F  PL+S+ A EG     +  +    +PT  + W K G  ++A+ R     +    
Sbjct: 3888 PQPVFREPLQSLQAEEGSTATLQCELS---EPTATVVWSKGGLQLQANGRREPRLQGCTA 3944

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR-ATIERTSQHPE 742
             L +  L  +D+GEYTC      G   T A L VT       R  QH E
Sbjct: 3945 ELVLQDLQREDTGEYTC----TCGSQATSATLTVTAAPVRFLRELQHQE 3989



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN--FGY 827
            P+F+  ++      EG +A F   +     P +R  WYKDG  +T  ++  ++     G 
Sbjct: 6108 PRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            + L I     ED G Y    VN+LG A ++A +R+
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 10/120 (8%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            AA +GY      +  E +    P F+ T  D       +   EC  +  + + +R  W  
Sbjct: 4881 AAFKGYK-----VRKEMKQQEGPMFSHTFGDTEAQVGDALRLEC--VVASKADVRARWLK 4933

Query: 3596 NGKPLLTGSR--VKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G  L  G    +  + D G   L I G+ + DAG YTC+ +N+ G+ T S  + V G +
Sbjct: 4934 DGVELTDGRHHHIDQLGD-GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSE 4992



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 2/72 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +  G+ A   C++  VG+PT +V W ++++ +   +R     D     +TI  +   D G
Sbjct: 21   VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSG 78

Query: 2448 VYMCRASNLLGE 2459
             Y+CRA N +GE
Sbjct: 79   QYVCRARNAIGE 90



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/76 (28%), Positives = 39/76 (51%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            +P  ++ W  + + +  G+RF+L  D     L ++D+   DSG Y C+A N  GEAF + 
Sbjct: 36   NPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95

Query: 3000 TVYCTSKDNLIERTQH 3015
             +   ++    E+  H
Sbjct: 96   GLQVDAEAACAEQAPH 111



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN------FPIKNSPDFQIHTFS 4463
            PP   ++  P +V +     F V+ +G P+P + W RE       +   ++P + + + +
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +  L++  V  +    +  +A N  G A CSA+L V
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 4/124 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYV 2035
            P+F   ++ +   EG       T+     P +R  WY +G  +  G++F+T  +   G +
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLL 6165

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L I  A  ED G Y C+  N +G A  ++ +++ +      +    ++L    E+ + E
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQE 6225

Query: 2096 RPKP 2099
               P
Sbjct: 6226 TKVP 6229



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R         L +      D+G YSC A    G   +S +L   
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSFQLHIT 1252

Query: 3142 D-KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            + K+   K +    + N    + G SA   C V        ++ WY +G+ +  S++++ 
Sbjct: 1253 EPKAVFAKEQL---VHNEVRTEAGASATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRI 1306

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             +      L +      D+GEY C A
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 9/156 (5%)

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            EV W   + Q+R     + +V E    +L +  +   D+G   C +R+    T+ Q  ++
Sbjct: 1838 EVVWRCGNTQLRVGKRFQ-MVAEGPVRSLTVLGLRAEDAGEYVCESRDD--HTSAQLTVS 1894

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V    +VV  KF+   ST+   EG         V      + W +DG  + P+ +  I  
Sbjct: 1895 V---PRVV--KFMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQ 1948

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
             G + +L I      DA      A+  + S A R R
Sbjct: 1949 SGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDF 2697
            Q+ P+F+ H     +   G  + LE  V  + D  ++  W K+GV LT G          
Sbjct: 4895 QEGPMFS-HTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD 4951

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  +L I  L   D+G YTC+ +N  G+   +A + +
Sbjct: 4952 GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 66/294 (22%), Positives = 104/294 (35%), Gaps = 34/294 (11%)

Query: 82  RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGD 140
           R  +G  A F  ++ G+P P VSW++    L E +   +R  E+ G+ S L I+   P D
Sbjct: 120 RVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRV-EELGEASALRIRAARPRD 178

Query: 141 EGEYTCTARNQYGEAICSVYIQPEGXXXXXXX---XXXXXXYRHVSETVE---------- 187
            G Y   A N  G A  +  +  +                   H+    E          
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPAS 238

Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSST---DDFKV-----------DTFEYRLLRE 233
             + GT+  T  + +  +   Y  G     T    D ++           D  E  +L+ 
Sbjct: 239 PPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKI 298

Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSG 291
           +  ++S    Y   +   +       L  V  P +  K R  + +++E   A F  ++  
Sbjct: 299 LFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVP- 357

Query: 292 NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            P     WFK   RL  S K+ I        L VRN    D   Y  + E P G
Sbjct: 358 QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVY--ICETPEG 409



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 80/375 (21%), Positives = 141/375 (37%), Gaps = 44/375 (11%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S   ++        L++++    D+  ++  A    G  + S +L V 
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVA 1620

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E +      +V        + V   +G    L  +V   +  +V W K+GKK+    + +
Sbjct: 1621 EPK------VVFAKEQPAHREVQAEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVR 1673

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL-PATKDKPKPQTKAAN 4620
            +     T  L++ +A   ++G+Y C A    G+       V  L P   ++P  +     
Sbjct: 1674 VEAVGCTRRLVVQQAGQAEAGEYSCEA---GGQQLSFRLQVAELEPQISERPCRR----- 1725

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
                  EPL   +V E + I  +  +      TV W K    I+ SK  + +   D +TL
Sbjct: 1726 ------EPL---VVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTL 1776

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYE-GQPA 4738
             +  A   D   Y C       RV    +     P Q + + A    L + V  E G   
Sbjct: 1777 TVHGAQVLDSAIYSC-------RVGAEGQ---DFPVQVEEVAAKFCRLLEPVCGELGGTV 1826

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC--RAT 4796
                +++      + W      +     FQM+ EG    L +     ED G + C  R  
Sbjct: 1827 TLACELSPACAEVV-WRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDD 1885

Query: 4797 TAAGQVETSAKLVVK 4811
              + Q+  S   VVK
Sbjct: 1886 HTSAQLTVSVPRVVK 1900



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            R    + V+  P  +T+   P    E QS    C   P P     V+WY +   L    +
Sbjct: 2457 RSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKA---VQWYKDDTPLSPSEK 2513

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++ S +   A L IL +   D+G Y C+A    G A SS  + V+++E
Sbjct: 2514 FKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVEARE 2557



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFV 3887
            PP F  ++   T E  E V+  CRV     PK  I WY++GK +     +  + D  G  
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 6070

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +L +  +   DSG+Y+C A +  G   T   I  +  P  +
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFV 6111



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP FE+   +     G   K   ++ G P PV+SW  K    V+ + + +   +  G  +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISW-YKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 131  LLIKQIGPGDEGEYTCTARNQYG 153
            L++  +   D G+Y C A +  G
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAG 6094



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EG++  F C +E +  P  +I W+ +   L +G ++++  +     + L I    +ED G
Sbjct: 6121 EGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2845 IYTCKATNSKGSATTSGSLR 2864
            +Y C+  N  GSA  S  LR
Sbjct: 6179 LYECELVNRLGSARASAELR 6198



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/67 (34%), Positives = 34/67 (50%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            +P  +V W  + + + AG+RFR   D     L I      DSG+Y+CRA N  GEA    
Sbjct: 36   NPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95

Query: 3509 SMKVQGK 3515
             ++V  +
Sbjct: 96   GLQVDAE 102



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG+ A +   +     P +R  WY +G  L  G++F+T  +   G + L I +    D G
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2580 LYMCKAINRAG 2590
            LY C+ +NR G
Sbjct: 6179 LYECELVNRLG 6189



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 145/671 (21%), Positives = 247/671 (36%), Gaps = 71/671 (10%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            +S    V  +PL  P    E +++ L C   P       V+W+ +   ++   +FK   +
Sbjct: 2464 VSDIPVVLTRPLE-PKTGRELQSVVLSCDFRPA---PKAVQWYKDDTPLSPSEKFKMSLE 2519

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT-DTQNEQAIEQ--I 1288
                 L I+    AD G Y  +A    GSAH+S  V V  R   VT   Q+ +A E+   
Sbjct: 2520 GQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWA 2575

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
                + +   ++V   +  M  P ++ + H I      +  +   +Q      +R     
Sbjct: 2576 SFSCELSHEDEEVEWSLNGM--PLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLK 2633

Query: 1349 NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN------------QLGEAVT 1396
                 +   R +P       ALD LS     +    C+ ++            QLG +  
Sbjct: 2634 VSTSARLEVRVKPVVFLK--ALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDK 2691

Query: 1397 SCALRVIAKKDLILESQHP--SGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIE 1454
               L     + L++    P  +GL       + +R  +  + D  V I  R     K++E
Sbjct: 2692 YDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETR-ARVRVHDLHVGITKRL----KTME 2746

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
             V+EG+   FEC L   + S+    W   G+ V    RF+         L + +    D+
Sbjct: 2747 -VLEGESCSFECVLSHESASD-PAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDA 2804

Query: 1515 G--IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDE 1572
            G  +++ R +    T + S  L  R     +     +  +   + +E R +  R      
Sbjct: 2805 GEVVFSVRGL----TSKAS--LIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVH 2858

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
                      S K   + EG  A    R   + DA    E+    +  KS +        
Sbjct: 2859 WLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAG---EYTCEVEASKSTASLHVEEKA 2915

Query: 1633 GFVALDIMSCLPEDSGT--YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRL-- 1688
                 ++ +   E+ GT  +TC+  +     VT    ++  + S   +   EG   RL  
Sbjct: 2916 NCFTEELTNLQVEEKGTAVFTCKTEHP-AATVTWRKGLLELRASGKHQPSQEGLTLRLTI 2974

Query: 1689 NQLE--DTSKYQRHSAQDEVITQAPV------FTMPMKDIRVAENQAAHFEARLIPVG-D 1739
            + LE  D+  Y     Q +   Q  V          ++D+ V E  +A F  R+ P   +
Sbjct: 2975 SALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYE 3034

Query: 1740 PKLRVEWLRNGVPIEASNRLTTM--HDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            P   V W  +  P+ A N L  +     GY  L ++ +  +DSGT       E G+   S
Sbjct: 3035 P---VHWFLDKTPLHA-NELNEIDAQPGGYHVLTLRQLALKDSGT----IYFEAGDQRAS 3086

Query: 1798 STLFVQSKASL 1808
            + L V  K S+
Sbjct: 3087 AALRVTEKPSV 3097



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 56/243 (23%), Positives = 94/243 (38%), Gaps = 23/243 (9%)

Query: 99   PTP-VVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
            P P  V W +   PL    K+ M    Q  ++ +L  ++ P D G Y C A    G A  
Sbjct: 2494 PAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRIL--RLMPADAGVYRCQA----GSAHS 2547

Query: 158  SVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSS 217
            S  +  E                  +E  E    G   ++ E S + ++V ++       
Sbjct: 2548 STEVTVEAREVTVTGPLQD------AEATEE---GWASFSCELSHEDEEVEWSLNGMPLY 2598

Query: 218  TDDFKVDTFEYRLLREVSFRESITKRYVG---ESDVQISTEIDRSLGPVSPPKIAQKPRN 274
             D F   + + R  R     +SI +   G    S +++ST     +  V P    +   +
Sbjct: 2599 NDSFHEISHKGR--RHTLVLKSIQRADAGIVRASSLKVSTSARLEVR-VKPVVFLKALDD 2655

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
               +E      Q ++S +P   V W K+G +L  S+K++ + T     L V +    D+G
Sbjct: 2656 LSAEERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAG 2714

Query: 335  HYT 337
             YT
Sbjct: 2715 LYT 2717



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/162 (22%), Positives = 66/162 (40%), Gaps = 10/162 (6%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +   EVTW+ + +++    + K+ +  +G    L++     +D+G  +
Sbjct: 905  GASATLSCEVA-QAQTEVTWYKDGKKLSS--SSKVCMEATGCTRRLVVQQAGQADAGEYS 961

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A    G       L+V E + V A   V   S +    G    L+       T  + W
Sbjct: 962  CEA----GGQRLSFHLDVKEPKVVFAKDQVAH-SEVQAEAGASATLSCEVAQAQT-EVMW 1015

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
             KDG  +  + ++ +   G    L + +A  +DA  Y C A+
Sbjct: 1016 YKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEAR 1057



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 82/367 (22%), Positives = 142/367 (38%), Gaps = 35/367 (9%)

Query: 1471 VTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEV 1530
            V+D    V W K+G  +    ++  +H  G   L + D+  ED+G+YTC     VG++E 
Sbjct: 2670 VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEET 2725

Query: 1531 SCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNV--- 1587
              R+        V  T+    L+ ++VLE  S      +  E  +   + T   K V   
Sbjct: 2726 RARVRVHDLH--VGITKR---LKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSS 2780

Query: 1588 ----EIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
                  ++G++     R    SDA  +V +       K+     E        L+     
Sbjct: 2781 SRFQATRQGRKYILVVREAAPSDAG-EVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVA 2839

Query: 1644 PEDSGTYTCRAINALGEAV---TSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKY-- 1697
            P +     C    A G  V       AI  S+K  +  E      + R   L+D  +Y  
Sbjct: 2840 PGEDVELRCELSRA-GTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTC 2898

Query: 1698 ----QRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753
                 + +A   V  +A  FT  + +++V E   A F  +      P   V W +  + +
Sbjct: 2899 EVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCK---TEHPAATVTWRKGLLEL 2955

Query: 1754 EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ 1813
             AS +     +   + L +  +   DS TYTC    ++G+A + + L VQ +    +E  
Sbjct: 2956 RASGKHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLVQGRRVHIIEDL 3011

Query: 1814 HESALQK 1820
             +  +Q+
Sbjct: 3012 EDVDVQE 3018



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 45/197 (22%), Positives = 79/197 (40%), Gaps = 15/197 (7%)

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            +++ +A     ++  QD  ++EG+   F CR++     E  W +    ++ +  + I V 
Sbjct: 4242 QLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVE 4301

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            +   H L +  VTL D+G V+       G  + + +L V  K  VV  + +E    L   
Sbjct: 4302 QGTLHLLTLHKVTLEDAGTVSF----HVGTCSSEAQLKVTAKNTVV--RGLENVEAL--- 4352

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            EG   +   +         TW  D  P+    N E+    +G    L +   +  D+   
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDS--- 4409

Query: 562  QCTAQNVAGSTATRARL 578
             C    +AG   T A L
Sbjct: 4410 -CRVTFLAGDMVTSAFL 4425



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 5/114 (4%)

Query: 941  LRVEWLKDGRPV-EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            +R  WLKDG  + +           G  +L I  +   DAG YTC+  N  GQ T SA  
Sbjct: 4927 VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSA-C 4985

Query: 1000 TIVTKKDIIAESQHPGGLEKIQYLEDASRYSK--RTEEEVKITQKPRFLGPLKG 1051
             +V+  +  AES   G L+   +   A R  +  RT+   +++ +  FL   +G
Sbjct: 4986 VVVSGSESEAESSSGGELDD-AFRRAARRLHRLFRTKSPAEVSDEELFLSADEG 5038



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 9/129 (6%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAG 980
            EG  A F   +E  G    ++ W KDG  +   ++  T      G + L I++ +  D G
Sbjct: 6121 EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGL-EKIQYLEDASRYSKRT---EEE 1036
             Y C   N +G A  SA L I +      E  H   L   ++  E  ++  K+T   EE 
Sbjct: 6179 LYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEET 6238

Query: 1037 V-KITQKPR 1044
            +  + + PR
Sbjct: 6239 ITTVVKSPR 6247



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            ++ EG  AH    L   G     +EW      +    + + V       L + G +  D+
Sbjct: 3989 EVDEGGTAHLCCELSRAGAS---VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA 4045

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            G Y+C   +    A +SV++         +P+F T +Q++E  + G  A   C +   + 
Sbjct: 4046 GDYTCDTGHTQSMASLSVRV--------PRPKFKTRLQSLE-QETGDIARLCCQLSDAES 4096

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              + ++W   G  +    + +  S      L I   +  D+GEY C
Sbjct: 4097 GAV-VQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC 4141



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 22/82 (26%), Positives = 35/82 (42%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F     D +   G   R +C V  +      W  +  ++ D  +H I     G  +L+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957

Query: 452  ITNVTLSDSGVVTCVARNKSGE 473
            IT +  +D+G  TC   NK G+
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQ 4979



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-ILI 4469
            P+F  ++Q   V +     F+    G+P+P ++W+++   ++    + I+        LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I  V   D  V+  +AEN  G +   A L V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 6/132 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++     V   G +    C +  +  PT ++ W  + +P+ +G R++   D     L I
Sbjct: 12   FLTRPKAFVVSVGKDATLSCQIVGN--PTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQH----PQGKAGLEAVEQAE 2891
                  DSG Y C+A N+ G A  +  L+   +        H    P      E  E   
Sbjct: 70   LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATF 129

Query: 2892 EARLAKGRRPSV 2903
              R+    RP+V
Sbjct: 130  RCRVGGSPRPAV 141



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 42/204 (20%), Positives = 80/204 (39%), Gaps = 11/204 (5%)

Query: 364  QDQRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            Q    +Y  +   +     ++++E K +  +   V ++     G  T   C V  +   E
Sbjct: 1414 QADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVA-QAQTE 1472

Query: 423  VTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            V W+ + +++   ++ K+ +   G    L++     + +G  +C A    G       L+
Sbjct: 1473 VMWYKDGKKL--SFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFHLH 1526

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V E + V A K       +    G    L+       T  +TW KDG  +  + ++R+  
Sbjct: 1527 VAEPKAVFA-KEQPASREVQAEAGTSATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEA 1584

Query: 542  DGGASTLDIPRAKASDAAWYQCTA 565
             G    L +  A  +DA  Y C A
Sbjct: 1585 VGCTRRLVVQEAGQADAGEYSCKA 1608



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            A +F R L  +    G  V L C L P       V W C    ++ G RF+   E    +
Sbjct: 1808 AAKFCRLLEPVCGELGGTVTLACELSPA---CAEVVWRCGNTQLRVGKRFQMVAEGPVRS 1864

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            L +L +  ED+G Y C++ +    A  + ++  + K
Sbjct: 1865 LTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVK 1900



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 13/122 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P KF   +++    E       C +  K  P   +EW++  + L  G R+    D     
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELS-KMAP---VEWWKGHETLRDGDRHSLRQDGARCE 3680

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  + AED+GEY+C      G++ T A ++ + +P   ++     G++  EA     A
Sbjct: 3681 LQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE-----GLRNEEATEGDTA 3731

Query: 3949 TI 3950
            T+
Sbjct: 3732 TL 3733



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 11/119 (9%)

Query: 1300 QVREDITV-MQAPQ--FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            Q R   T+ ++APQ  F   L +++  EG+   L+C L    + T  V W   G  ++  
Sbjct: 3876 QERTSATLTVRAPQPVFREPLQSLQAEEGSTATLQCELS---EPTATVVWSKGGLQLQAN 3932

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL-ESQH 1414
             R  P  +     L L  +  ED+G YTC      G   TS  L V A     L E QH
Sbjct: 3933 GRREPRLQGCTAELVLQDLQREDTGEYTCTC----GSQATSATLTVTAAPVRFLRELQH 3987



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTL 4571
            P F+ T  +     G  +RL+  V     +   WLK+G ++  D R+  +++  DGT +L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT-DGRHHHIDQLGDGTCSL 4956

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            LI      D+G Y C   N  G+    A  VVS
Sbjct: 4957 LITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGF 3752
            PP F  E+ D      G  V   CRV   G P   I W+ +G+          + D  G 
Sbjct: 6013 PPDFEEELAD-CTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGS 6069

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             AL +D +   D+G+Y C A +  G+ +T  KI
Sbjct: 6070 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKI 6102



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R   A  M  L +      D+G Y+C A    G   +S  L+ V
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRLSFHLD-V 1343

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             + K    +     + ++  + G  A   C V        ++ WY +G+ +  S++++  
Sbjct: 1344 SEPKAVFAKEQLAHRKVQA-EAGAIATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRME 1399

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            +      L +      D+GEY C A
Sbjct: 1400 AVGCTRRLVVQQACQADTGEYSCEA 1424



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165
            +AR   V   L DA   EEG WA F C ++ H    V W LNG  + N S +++++ G  
Sbjct: 2554 EAREVTVTGPLQDAEATEEG-WASFSCELS-HEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611

Query: 4166 HFDIPKTRQ 4174
            H  + K+ Q
Sbjct: 2612 HTLVLKSIQ 2620



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP FV+   A    EGE A+F C + G P P++ W  +G  +  G++++
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
           ES +++       L    PP  A +   ++L E  +AQ   +LS +    VTW K+G+ L
Sbjct: 690 ESSIRMEVRAAPGLTANKPPAAAAREVLARLHE--EAQLLAELS-DQAAAVTWLKDGRTL 746

Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               K+E+  +     L VR+  + D+G Y
Sbjct: 747 SPGPKYEVQASAGRRVLLVRDVARDDAGLY 776



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 11/175 (6%)

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            F K  + + V E      +  +T RP+PE+ W  N   +    N +I   E   H L++ 
Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHA-EGARHRLVLH 2047

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV  +D G   C    ++ +   Q +L V E  QV   + V     +  RE     +  +
Sbjct: 2048 NVGFADRGFFGC----ETPDDKTQAKLTV-EMRQV---RLVRGLQAVEAREQGTATMEVQ 2099

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
                     +W +DG+     P   +   G   TL +   +  D+      A+ V
Sbjct: 2100 LSHADVDG-SWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGV 2153



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371
            +F  AL ++E +EG    L C L  V      V+W      ++ G ++    E   + L 
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELV 3242

Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            + ++ P+DSG Y+C      G+  TS  L V A
Sbjct: 3243 VRNLRPQDSGRYSC----SFGDQTTSATLTVTA 3271



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
            +P F  PLQ L + +EG  A  + +L   S+PT  V W K G  + A+ R          
Sbjct: 3889 QPVFREPLQSL-QAEEGSTATLQCEL---SEPTATVVWSKGGLQLQANGRREPRLQGCTA 3944

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             L +  L+ ED G YT    ++   A  T +
Sbjct: 3945 ELVLQDLQREDTGEYTCTCGSQATSATLTVT 3975



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            Q  +A+ K   +++    Q+R  + + V + P F  +L   T    G++    CR+   P
Sbjct: 5985 QARTAIIKSSWVKEICGIQQR--LALPVWRPPDFEEELADCTA-ELGETVKLACRVTGTP 6041

Query: 1873 DPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             P   + WY +GK +Q   H     +  G  AL + ++ G DSG+Y C A +  G   + 
Sbjct: 6042 KPV--ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTL 6099

Query: 1932 IRLNVQ 1937
             ++ VQ
Sbjct: 6100 GKILVQ 6105



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 77/397 (19%), Positives = 149/397 (37%), Gaps = 37/397 (9%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            E  +K +      + ++     E  +A FE +     +    W  ++ P+  S + ++  
Sbjct: 4331 EAQLKVTAKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVF 4390

Query: 4462 FST--KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            F    + +L+++ +  +DS     +A    G    SA L V   R +    I+ P     
Sbjct: 4391 FENGLRHLLLLKNLRPQDSCRVTFLA----GDMVTSAFLTVRGWRLE----ILEP----- 4437

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGT-YTLLILEAY 4577
             +N  V +G        ++   P+ +  W  NG  VQPD  +  +  DG+ + LL+  A 
Sbjct: 4438 LKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQ 4497

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
            P  +G+      ++   AR     V+ LP   D P+     A +   +        +++G
Sbjct: 4498 PHHAGEVTFACRDAVASARL---TVLGLP---DPPEDAEVVARSSHTVTLSWAAP-MSDG 4550

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIK-PSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
                   ++  K   T QW    +L+  P          + Y  R++   P   G+    
Sbjct: 4551 GGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGE---- 4606

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
              +    V +A   K   P      P+    R +    G+    + ++ ++    I W +
Sbjct: 4607 PVHLPQTVRLAEPPKPVPPQ-----PSAPESRQVAA--GEDVSLELEVVAEAGEVI-WHK 4658

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                I     F+++ +G   +L+I     ED G + C
Sbjct: 4659 GMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 11/151 (7%)

Query: 4585 ECVAINSA-GEA-RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL----KDKIVAEGQ 4638
            ECV    A GE  R     V  + A +    PQT     PP+ + P     + + VA G+
Sbjct: 4580 ECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGE 4639

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC-VA 4697
             +    ++V +    + W+KG + I+P   F++     +  L I     ED+G+Y C +A
Sbjct: 4640 DVSLELEVVAEAGEVI-WHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLA 4698

Query: 4698 YNS--AGRVTVAAKLKVTQPDQADNLPALTP 4726
              S      T    L     D+A   P+L P
Sbjct: 4699 QGSICPAAATFQVALSPASVDEAPQ-PSLPP 4728



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/151 (23%), Positives = 51/151 (33%), Gaps = 4/151 (2%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            V PE +     +   PVF++      V++G    F C VTG P P V W  +G  +    
Sbjct: 5111 VPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD 5170

Query: 4156 RYKLTYD--GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNA 4213
             Y +  D  G +   I      D G    +             L+V     DY       
Sbjct: 5171 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADAT 5230

Query: 4214 PRPWYDETTQY--QRTETELEKTFEERQVLQ 4242
                Y     Y   R +   E T +E Q+ Q
Sbjct: 5231 ESSSYFSAQGYLSSREQEGTESTTDEGQLPQ 5261



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            PRF+T+ ++    V  + T   CQ+  VG+P  +V W  + +P+    RF    D     
Sbjct: 10   PRFLTRPKAFVVSVGKDAT-LSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 4033 MNFGWVYPEDSGEYLCRATNLYG 4055
            +    +   DSG+Y+CRA N  G
Sbjct: 67   LTILDLALGDSGQYVCRARNAIG 89



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R         L +      D+G YSC+A    G   +S  L   
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVA 1620

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            +           H + ++  + G SA   C V        ++ WY +G+ +  S++++  
Sbjct: 1621 EPKVVFAKEQPAH-REVQA-EAGASATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRVE 1675

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            +      L +      ++GEY C A
Sbjct: 1676 AVGCTRRLVVQQAGQAEAGEYSCEA 1700



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 12/111 (10%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            ++W+ +   +  S + +      M  L IL     D+G Y C+A +     E++V     
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTV----- 2553

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++   T  +Q+ E  ++G  A F C    +   D ++EW  NG P+
Sbjct: 2554 ---EAREVTVTGPLQDAEATEEGW-ASFSC---ELSHEDEEVEWSLNGMPL 2597



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 7/97 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P   I PL+      G  +     +   G P   + WLK+ ++I  S ++  +       
Sbjct: 2826 PAAIIKPLEDQWVAPGEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAM 2882

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            L +   +++D+GEYTC   +    +++ A LHV  +A
Sbjct: 2883 LVIRGASLKDAGEYTCEVEA----SKSTASLHVEEKA 2915



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 43/172 (25%), Positives = 64/172 (37%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +T+    R           L+I G    D+G YSC      GQ   S  L   
Sbjct: 3743 VEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVC----GQERTSATLTV- 3797

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
               +    RF   ++N E  ++G +A  +C +         +EW    + +R   R    
Sbjct: 3798 ---RALPARFIEDVKNQEA-REGATAVLQCEL----SKAAPVEWRKGSETLRGGDRYSLR 3849

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             D     L I      D+GEY C      G++ T AT+       V+ E LQ
Sbjct: 3850 QDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVRAPQPVFREPLQ 3897



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 17/143 (11%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S ++ V  P+++    + E      + EG+ A F+C++        R      G  LQ+ 
Sbjct: 4240 SAQLTVRAPEVT----ILEPLQDVQLSEGQDASFQCRLSRASGQEARWAL--GGVPLQAN 4293

Query: 2289 ARFHITFDFGYVSLDIQHCVP-EDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
                IT + G + L   H V  EDAG  S      +G C+S   + VTAK +++      
Sbjct: 4294 EMNDITVEQGTLHLLTLHKVTLEDAGTVSFH----VGTCSSEAQLKVTAKNTVV------ 4343

Query: 2348 EGLEKIRELESAEPFKRPEIPEP 2370
             GLE +  LE  E     ++ +P
Sbjct: 4344 RGLENVEALEGGEALFECQLSQP 4366



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+S L+ +V +EG    F+C V PS    + + WF +   L    ++  +   +  SL I
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPS---DVAVVWFRDGALLQPSEKFAISQSGASHSLTI 1957

Query: 2836 THTYEEDSGIYTCKATNSKGSA 2857
            +    ED+G  T +A  +  SA
Sbjct: 1958 SDLVLEDAGQITVEAEGASSSA 1979



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 57/275 (20%), Positives = 105/275 (38%), Gaps = 35/275 (12%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V     + V W ++G  +QP  +  I +   +++L I +   +D+G+   + + + G + 
Sbjct: 1921 VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ---ITVEAEGASS 1977

Query: 4597 CDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
              A  V   P   K K +PQT                 V E  ++    ++  +P P ++
Sbjct: 1978 SAALRVREAPVLFKKKLEPQT-----------------VEERSSVTLEVELT-RPWPELR 2019

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            W +    + P K  ++      + L +      D G + C   +   +    AKL V   
Sbjct: 2020 WTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ----AKLTV--- 2072

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
             +   +  +  L+ +   E   A  + Q+ S       W R+G    + P   +   G  
Sbjct: 2073 -EMRQVRLVRGLQAVEAREQGTATMEVQL-SHADVDGSWTRDGLRFQQGPTCHLAVRGPM 2130

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              L +     ED+G    +A      V TSA+LVV
Sbjct: 2131 HTLTLSGLRPEDSGLMVFKAE----GVHTSARLVV 2161



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 5/70 (7%)

Query: 804  VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            V+WYKD  P++ S +           L I+ L   DAG Y  +A    G A S+  + V 
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 864  ARS-TVTADL 872
            AR  TVT  L
Sbjct: 2555 AREVTVTGPL 2564



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 32/126 (25%), Positives = 56/126 (44%), Gaps = 11/126 (8%)

Query: 2617 EQIQLKEAAMNKVPEMFVDTG----VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            + IQ  +A + +   + V T     V+  P+    LK+ D L   +   L  Q E  +DP
Sbjct: 2617 KSIQRADAGIVRASSLKVSTSARLEVRVKPV--VFLKALDDLSAEERGTLALQCEV-SDP 2673

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
               + W K+GV L    +       G   L ++ +  +D+G+YTC     +G   + A +
Sbjct: 2674 EAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARV 2729

Query: 2733 KIEDRH 2738
            ++ D H
Sbjct: 2730 RVHDLH 2735



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 11/126 (8%)

Query: 1815 ESALQKIQQLEDSSRY-----QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRI 1868
            E  LQ +Q+ ED+  Y      +     + V  AP RF+ +L    ++ EG +AH  C +
Sbjct: 3945 ELVLQDLQR-EDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQ-EVDEGGTAHLCCEL 4002

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
                     VEW      L    +Y+   D   A L +  V  ED+G+YTC   +    A
Sbjct: 4003 SR---AGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMA 4059

Query: 1929 VSSIRL 1934
              S+R+
Sbjct: 4060 SLSVRV 4065



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 35/166 (21%), Positives = 63/166 (37%), Gaps = 10/166 (6%)

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            +Y   T  ++T   + ++E  +    V+   D +VT  +   F C V+      V W + 
Sbjct: 4138 EYACVTGGQKTAASLRVTEPEVT--IVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQ 4195

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
               ++ +   ++ V +   H L +  VT  D+G V+       G  A   +L V   E  
Sbjct: 4196 GLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF----HLGNHASSAQLTVRAPEVT 4251

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534
            +    +E    + + EG+      R          W   GVP+  N
Sbjct: 4252 I----LEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQAN 4293



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 4/106 (3%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG-HRYRT 1895
            E+   + P F +   G T+   G +   EC +    D  +R  W  +G  L  G H +  
Sbjct: 4891 EMKQQEGPMF-SHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHID 4947

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
                G  +L I  +   D+G YTC+  N  GQ   S  + V   ES
Sbjct: 4948 QLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSES 4993



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   ++  +   + G   +   +++G P+P ++W+K+G+ +     H +I   + +   
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 325  VRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESP 358
            + ++    DSG Y   A +  G   T G + V+ P
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 16/201 (7%)

Query: 2538 PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXX 2597
            P++   W  +GVEL+ G            +L I      D G+Y+C A +          
Sbjct: 2192 PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHD---AQSSASV 2248

Query: 2598 XXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEG 2657
                    +I + +  E   +IQ    A N   E      V++ P+ T      DK+   
Sbjct: 2249 KVQGRTYTLIYRRVLAEDAGEIQF--VAEN--AESRAQLRVKELPV-TLVRPLRDKIAME 2303

Query: 2658 QH-VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            +H   LE QV   +  + ++ WFK    L  G + +   D     L I+ +  +D   YT
Sbjct: 2304 KHRGVLECQV---SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYT 2360

Query: 2717 CKATNLLGEAVSTASIKIEDR 2737
            C A    G+  ++A   +E++
Sbjct: 2361 CDA----GDVKTSAQFFVEEQ 2377



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 8/96 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P RF   +KD ++V EGG     C +  V  P   + W +       G +     +   +
Sbjct: 3184 PVRFQEALKD-LEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAML 3239

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
             L +  +  +D+G Y+C     +G  TT+A +T +A
Sbjct: 3240 ELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTA 3271



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 7/87 (8%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            +LK++E+ EG  A    R + +S     V+W + N  L+ G +++       + L + + 
Sbjct: 3190 ALKDLEVLEGGAATL--RCV-LSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNL 3246

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIV 1669
             P+DSG Y+C    + G+  TS    V
Sbjct: 3247 RPQDSGRYSC----SFGDQTTSATLTV 3269



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 6/109 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P K  +  RN +  EGA A  + +LS      V W+K  + L + ++H +        L+
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELS--KMAPVEWWKGHETLRDGDRHSLRQDGARCELQ 3682

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            +R     D+G Y  +     G   TS  L V +    +++  R++  T+
Sbjct: 3683 IRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLRNEEATE 3727



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 9/124 (7%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P KFI  +++    E +     C +  K  P   +EW +  + L  G R+    D     
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS-KAAP---VEWRKGHETLRDGDRHSLRQDGSRCE 3768

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  +   D+GEY C      G++ T AT++ + LP   +++ V     R  A   ++ 
Sbjct: 3769 LQIRGLAVVDAGEYSCVC----GQERTSATLTVRALPARFIED-VKNQEAREGATAVLQC 3823

Query: 3949 TIKK 3952
             + K
Sbjct: 3824 ELSK 3827



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 7/121 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L N    EGD     C +  +      +EW   ++ L  G R+    D S   L I
Sbjct: 3716 FIEGLRNEEATEGDTATLWCELSKAAP----VEWRKGHETLRDGDRHSLRQDGSRCELQI 3771

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                  D+G Y+C     + SAT   ++R    + I  D ++ + + G  AV Q E ++ 
Sbjct: 3772 RGLAVVDAGEYSCVCGQERTSATL--TVRALPARFIE-DVKNQEAREGATAVLQCELSKA 3828

Query: 2896 A 2896
            A
Sbjct: 3829 A 3829



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 10/116 (8%)

Query: 1831 QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Q R    + V   P RFI  +    +  EG +A  +C +         VEW    + L+ 
Sbjct: 3788 QERTSATLTVRALPARFIEDVKNQ-EAREGATAVLQCELSKAAP----VEWRKGSETLRG 3842

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
            G RY    D     L I  +   D+GEY+C      GQ  +S  L V++ + + R+
Sbjct: 3843 GDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVRAPQPVFRE 3894



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 38/146 (26%), Positives = 59/146 (40%), Gaps = 12/146 (8%)

Query: 1385 CQATNQLGEAVTSCA---LRVIAKKDLILESQHPSGLEKIQYLEDTSRY---KKTDIIDE 1438
            C+ +    E V  C    LRV  +  ++ E    S        ED   Y    + D    
Sbjct: 1830 CELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSA 1889

Query: 1439 SVTIK-PRFVTRPKSIENVI--EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
             +T+  PR V     +  V+  EG    F+C + P   S++ V WF++G  +    +F  
Sbjct: 1890 QLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAI 1946

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRA 1521
                   +L I DL+ ED+G  T  A
Sbjct: 1947 SQSGASHSLTISDLVLEDAGQITVEA 1972



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 76/330 (23%), Positives = 129/330 (39%), Gaps = 41/330 (12%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P  F+  +   + EE   +  +C V    DP+  + W ++G  L    +Y  ++  G   
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCEVS---DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG 2702

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L +  V  ED+G Y C      G + T+A +   ++ D  L   + + +K  E L     
Sbjct: 2703 LVVHDVSPEDAGLYTCHV----GSEETRARV---RVHD--LHVGITKRLKTMEVLEGESC 2753

Query: 3949 TIKKYTSEVYLTEDDLYDVDKK---QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNM 4005
            + +   S    ++  ++ V  K      RF    Q +  ++ +     E   +  G+   
Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVR----EAAPSDAGEVVF 2809

Query: 4006 KVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCR----ATNLYGMDETKA 4061
             V    +   L+ + R   I       +   WV P +  E  C      T ++ + + KA
Sbjct: 2810 SVRGLTSKASLIVRERPAAIIK----PLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKA 2865

Query: 4062 VIKTTGKPGIVYDSQLP------KHMKSI-EKIREMEASWQVTPEQVVEESKARCPPVFV 4114
            + K+  K  +V +  +         +K   E   E+EAS + T    VEE KA C   F 
Sbjct: 2866 IRKSQ-KYDVVCEGTMAMLVIRGASLKDAGEYTCEVEAS-KSTASLHVEE-KANC---FT 2919

Query: 4115 SLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
                 + VEE   A F C+ T HP   V W
Sbjct: 2920 EELTNLQVEEKGTAVFTCK-TEHPAATVTW 2948



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 8/110 (7%)

Query: 1974 VVEKPQ-FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V EKP  F + + +A +TEG  + L    +  + P   V W  +G+ ++   R + +++ 
Sbjct: 3091 VTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP---VCWTKDGKTLRGSARCQLSHEG 3147

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082
                L I  A  +D+G Y C+A    G A ++S V+V A+   + + L +
Sbjct: 3148 HRAQLLITGATLQDSGRYKCEA----GGACSSSIVRVHARPVRFQEALKD 3193



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            I + P +FI  +K+    E      +C +         +EW +  + L  G RY    D 
Sbjct: 3533 IRALPARFIEDVKNQEAREGATAVLQCELNSAAP----VEWRKGSETLRDGDRYSLRQDG 3588

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+GEY C      G++ T A ++ + LP
Sbjct: 3589 TKCELQIRGLAMADTGEYSCVC----GQERTSAMLTVRALP 3625



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 9/124 (7%)

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            Q R    + V   P   T+     + +EG +A   C +         VEW+   + L+ G
Sbjct: 3612 QERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDG 3667

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES-IIRDSQHE 1949
             R+    D     L I  +  ED+GEY C      G+  +S  L V++  S  I   ++E
Sbjct: 3668 DRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLRNE 3723

Query: 1950 SALE 1953
             A E
Sbjct: 3724 EATE 3727



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 9/101 (8%)

Query: 1454 ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAED 1513
            E   EG      C+L  +      VEW+K  + +  G R     D     L I  L+AED
Sbjct: 3635 EEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAED 3690

Query: 1514 SGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLE 1553
            +G Y C    + G +  S  LT R+  +  +   +NE   E
Sbjct: 3691 AGEYLC----MCGKERTSAMLTVRAMPSKFIEGLRNEEATE 3727



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++          L +     TD+G YSC A    GQ  +S +L   
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEAR---GQ-RVSFRLHIT 1068

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            +         + H  N    + G SA   C V        ++ WY +G+ +  S+++   
Sbjct: 1069 EPKMMFAKEQSVH--NEVQAEAGASAMLSCEVA---QAQTEVTWYKDGKKLSSSSKVGME 1123

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
                   L +      D+GEY C A
Sbjct: 1124 VKGCTRRLVLPQAGKADAGEYSCEA 1148



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P  F++  K+    +GG A     L     PV  W      L   +KYS+R  ++   + 
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGDKYSLR--QEGAMLE 3240

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163
            L+++ + P D G Y+C+  +Q   A  +V   P
Sbjct: 3241 LVVRNLRPQDSGRYSCSFGDQTTSATLTVTALP 3273



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 8/97 (8%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P  FI +++     E       C +  K  P   +EW +  + L  G R+    D     
Sbjct: 3361 PAHFIGRLRHQESIEGATATLRCELS-KAAP---VEWRKGRESLRDGDRHSLRQDGAVCE 3416

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L I  +   D+GEY C      GE+ T AT++ K LP
Sbjct: 3417 LQICGLAVADAGEYSCVC----GEERTSATLTVKALP 3449



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 38/172 (22%), Positives = 67/172 (38%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +T+    R           L+I G    D+G YSC    +   A ++V+   +
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPI 3626

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                    +FT  ++N E   +G +A   C +  +      +EW+   + +R   R    
Sbjct: 3627 --------KFTEGLRNEEAT-EGATAVLRCELSKM----APVEWWKGHETLRDGDRHSLR 3673

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             D     L I      D+GEY+C      G++ T A +        ++E L+
Sbjct: 3674 QDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLR 3721



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 9/108 (8%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV   P +F+  L N E  EG    L C L  +      VEW+   + ++ G R     
Sbjct: 3619 LTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQ 3674

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILE 1411
            +     L +  +  ED+G Y C      G+  TS  L V A     +E
Sbjct: 3675 DGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE 3718



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 8/94 (8%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P +FI  +K+    E      +C +  K  P   +EW +  + L  G RY    D     
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCELS-KAAP---VEWRKGSETLRGGDRYSLRQDGTRCE 3856

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            L I  +   D+GEY C      G++ T AT++ +
Sbjct: 3857 LQIHGLSVADTGEYSCVC----GQERTSATLTVR 3886



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 60/272 (22%), Positives = 105/272 (38%), Gaps = 29/272 (10%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F +  ++ +  +G  A  + +L   PT  V W++    L    +   R    T +  L
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAE--L 3946

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            +++ +   D GEYTCT  +Q   A  +V   P               ++ V E       
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLTVTAAP-------VRFLRELQHQEVDEG------ 3993

Query: 192  GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE--SD 249
            GT     E SR    V +  G    S   F     +Y+++++ +  E + +    E   D
Sbjct: 3994 GTAHLCCELSRAGASVEWRKG----SLQLF--PCAKYQMVQDGAAAELLVRGVEQEDAGD 4047

Query: 250  VQISTEIDRSLGPVS----PPKIAQKPRNSKLQEGADAQFQVQLS-GNPRPRVTWFKNGQ 304
                T   +S+  +S     PK   + ++ + + G  A+   QLS       V W K G 
Sbjct: 4048 YTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGV 4107

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L    K+E+ +      L +   +  D+G Y
Sbjct: 4108 ELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 6/108 (5%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G   T  TLT  A    P  F        + E  +AH  C L     S   VEW      
Sbjct: 3964 GSQATSATLTVTAA---PVRFLRELQHQEVDEGGTAHLCCELSRAGAS---VEWRKGSLQ 4017

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
            L   ++ + + D     L + GV Q DAG YTC   +    A++S ++
Sbjct: 4018 LFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP F       T E GE  +  CRVTG PKP + W  +G  +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAV 6054



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/56 (32%), Positives = 28/56 (50%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            VG+P+ +  W  +   +  G+RFR   D     L I  +   D+G Y+C+A N  G
Sbjct: 34   VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIG 89



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 7/122 (5%)

Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
           VGE  V     +       +  ++A+  R  + + GA A    +++   +  VTW+K+G+
Sbjct: 872 VGEDSVDFRLRVSEPKVVFAKEQLAR--RKLQAEAGASATLSCEVA-QAQTEVTWYKDGK 928

Query: 305 RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           +L +S+K  +  T     L V+   ++D+G Y+  A    G    S +L V+ P   + +
Sbjct: 929 KLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA----GGQRLSFHLDVKEPKVVFAK 984

Query: 365 DQ 366
           DQ
Sbjct: 985 DQ 986



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 58/241 (24%), Positives = 96/241 (39%), Gaps = 21/241 (8%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVS-LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            V+W +    L   +K  M   E  G    L++++ G  D GEY+C A +Q       V  
Sbjct: 1565 VTWYKDGKKLSSSSKVRM---EAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHV-A 1620

Query: 162  QPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF 221
            +P+              +R V    E  A  T      Q+ QT+   Y +G   SS+   
Sbjct: 1621 EPK-----VVFAKEQPAHREVQ--AEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKV 1672

Query: 222  KVDTF--EYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKP-RNSKL- 277
            +V+      RL+ + + +    +        Q+S  +  +      P+I+++P R   L 
Sbjct: 1673 RVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVA---ELEPQISERPCRREPLV 1729

Query: 278  -QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +E  D      L+      VTW K+G  +  S +HE  +  +  TL V   Q  DS  Y
Sbjct: 1730 VKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIY 1789

Query: 337  T 337
            +
Sbjct: 1790 S 1790



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 45/172 (26%), Positives = 72/172 (41%), Gaps = 13/172 (7%)

Query: 2245 VTELRGTTHVFEGKTAHFECQV--EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
            +T+   T  V EG++  FEC +  E   DP +   +   GK + S++RF  T       L
Sbjct: 2738 ITKRLKTMEVLEGESCSFECVLSHESASDPAM---WTVGGKTVGSSSRFQATRQGRKYIL 2794

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPF 2362
             ++   P DAGE  V ++  L   TS  S+ V  + + I +    + +    ++E     
Sbjct: 2795 VVREAAPSDAGEV-VFSVRGL---TSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL 2850

Query: 2363 KRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCR---LIPVGDPTLKVE 2411
             R   P    + R    +  Q  D + EG  A    R   L   G+ T +VE
Sbjct: 2851 SRAGTPVHWLKDRKAIRKS-QKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 7/90 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KD+ V E  AA     L  V  P   V+W      +   ++ +   +   + L +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVV 3243

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            + + P+DSG Y+C      G+  TS+TL V
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTV 3269



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + + P +FI ++++    E       C +  K  P   +EW +  + L  G RY    D 
Sbjct: 3269 VTALPAQFIGKLRNKEATEGATATLRCELS-KAAP---VEWRKGSETLRDGDRYCLRQDG 3324

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+ EY C      GE+ T A+++ + +P
Sbjct: 3325 AMCELQIRGLAMVDAAEYSCVC----GEERTSASLTIRPMP 3361



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            K  ++  E ++   P F+    D  +   G  +  +C V    D  +R  W  +G     
Sbjct: 4884 KGYKVRKEMKQQEGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVELTD 4940

Query: 3741 GSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            G   H   L D G  +L I  +   DAG YTC+ +NK+G  T +A +  S
Sbjct: 4941 GRHHHIDQLGD-GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS--NRLTTMHDFG 1766
            + P+F+    D       A   E  +    D  +R  WL++GV +     + +  + D G
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD-G 4952

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
              +L +  ++  D+G YTC+  N+ G+ VT S   V S +  + ES
Sbjct: 4953 TCSLLITGLDRADAGCYTCQVSNKFGQ-VTHSACVVVSGSESEAES 4997



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 6/125 (4%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK-NGQRLI-----NSNKHEIITTH 318
            PP++ ++    K+++G+   F V++ G P P V W +   +R +     ++  + + ++ 
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 319  NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378
               +L + +  +   G YT +A N  G  + S  L V    +   Q++  + +  T  + 
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQG 5489

Query: 379  TEERI 383
            T + I
Sbjct: 5490 TTQAI 5494



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 12/117 (10%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI- 694
            PP+ +         +G  I F  ++E  G P   + WL+  +  E    +      GY  
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVE--GRPVPTVHWLR--EEAERGVLWIGPDTPGYTV 5425

Query: 695  -------SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
                   SL +L +  Q  G YTC A +A G A   A LHV+    +E   +  E L
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEAL 5482



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/90 (25%), Positives = 40/90 (44%)

Query: 4724 LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNT 4783
            LT  +  VV  G+ A    QI     P + W ++   +     F++  +G+   L I + 
Sbjct: 13   LTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDL 72

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               D+G + CRA  A G+   +  L V ++
Sbjct: 73   ALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 49/215 (22%), Positives = 84/215 (39%), Gaps = 18/215 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P  F+  ++D +   E   V  +C +     P + + W  +G     G  +         
Sbjct: 2165 PVSFSRPLQDVVTT-EKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACR 2220

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEK--IKEL 3811
            +L I      D G Y C A +    A ++A +    +   ++  ++    +GE   + E 
Sbjct: 2221 SLTIYRCEFADQGVYVCDAHD----AQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAEN 2276

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
               R     KE P+    P    +I    +E+  GV  EC+V        ++ W++  + 
Sbjct: 2277 AESRAQLRVKELPVTLVRP-LRDKI---AMEKHRGV-LECQVSRAS---AQVRWFKGSQE 2328

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906
            L  G +Y  V D  +  L I  V+AED   Y C A
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 47/224 (20%), Positives = 82/224 (36%), Gaps = 29/224 (12%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RP  F    KD+ ++ EG  A     L      +  ++W Y    +    +        M
Sbjct: 3183 RPVRFQEALKDL-EVLEGGAATLRCVL---SSVAAPVKWCYGNNVLRPGDKYSLRQEGAM 3238

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            + L +   +  DSG YSC   ++   A ++V             +F   ++N E   +G 
Sbjct: 3239 LELVVRNLRPQDSGRYSCSFGDQTTSATLTVT--------ALPAQFIGKLRNKEAT-EGA 3289

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A   C +         +EW    + +R   R     D     L I      D+ EY C 
Sbjct: 3290 TATLRCELSKA----APVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCV 3345

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269
                 GE+ T A++         +  +    + ++R  ES++GA
Sbjct: 3346 C----GEERTSASLT--------IRPMPAHFIGRLRHQESIEGA 3377



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PKF T+++S   E  +  R  C++   E   + ++W + G  L +G +Y          L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAV-VQWLKEGVELHAGPKYEMRSQGATREL 4126

Query: 3890 DILYVYAEDSGEYIC 3904
             I  + A+D+GEY C
Sbjct: 4127 LIHQLEAKDTGEYAC 4141



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFGYVA 2036
            P F + + +     G  V L   +T    P   + WY +G+ VQ   H        G  A
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +      D+G YMC A +A G   T   + V
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 9/115 (7%)

Query: 1825 EDSSRY--QRREDVEVA--VNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRV 1878
            ED+  Y  + R+D   A      PR +  ++G + +   EG  A ++C + P    ++ V
Sbjct: 1873 EDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP---SDVAV 1929

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             W+ +G +LQ   ++  S      +L I  +  ED+G+ T +A      A   +R
Sbjct: 1930 VWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P  F+  L  ++A E G +  +     V DP   + W K+G  +  S ++  +   G   
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG 2702

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +  ++ +D+G YTC      G  ET+A + V
Sbjct: 2703 LVVHDVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 7/123 (5%)

Query: 1831 QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Q R    + +   P RFI  +    +  EG +A  +C +         VEW    + L+ 
Sbjct: 3524 QERTSATLTIRALPARFIEDVKNQ-EAREGATAVLQCELNSAAP----VEWRKGSETLRD 3578

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR-LNVQSKESIIRDSQH 1948
            G RY    D     L I  +   D+GEY+C        A+ ++R L ++  E +  +   
Sbjct: 3579 GDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEAT 3638

Query: 1949 ESA 1951
            E A
Sbjct: 3639 EGA 3641



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 1581 TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIM 1640
            T  L+N E  EG  A     L  ++     VEW+  ++ L+ G R +   +     L I 
Sbjct: 3629 TEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQIR 3684

Query: 1641 SCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE 1678
              + ED+G Y C      G+  TS +  V +  S ++E
Sbjct: 3685 GLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE 3718



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            RP F T L SLE  + GD A   C++    +    + W   G ++ AG +Y         
Sbjct: 4067 RPKFKTRLQSLEQ-ETGDIARLCCQLSDA-ESGAVVQWLKEGVELHAGPKYEMRSQGATR 4124

Query: 2168 ALDILYTYAEDSGTYMC 2184
             L I    A+D+G Y C
Sbjct: 4125 ELLIHQLEAKDTGEYAC 4141



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 49/191 (25%), Positives = 77/191 (40%), Gaps = 21/191 (10%)

Query: 1678 ESQHEGALPRL--NQLE--DTSKY------QRHSAQDEVITQAPVFTMPMKDIRVAENQA 1727
            E + +GA   L  +QLE  DT +Y      Q+ +A   V          + D  V  ++ 
Sbjct: 4116 EMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADED 4175

Query: 1728 AHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT--TMHDFGYVALNMKYVNPEDSGTYTC 1785
              F   +   G     V+W   G+P++ SN +T   + D     L +K V PED+GT + 
Sbjct: 4176 VEFSCEVSRAG--ATGVQWCLQGLPLQ-SNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF 4232

Query: 1786 RAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEV--AVNQA 1843
                 LG   +S+ L V++     LE   +  L + Q      R  R    E   A+   
Sbjct: 4233 ----HLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGV 4288

Query: 1844 PRFITQLNGPT 1854
            P    ++N  T
Sbjct: 4289 PLQANEMNDIT 4299



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 6/112 (5%)

Query: 753  YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
            +  Y+ ++ +++Q  + P F     D  E Q G     E  +   +D  +R  W KDG  
Sbjct: 4883 FKGYKVRKEMKQQ--EGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVE 4937

Query: 813  IT-ASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            +T            G  SL I  L   DAG YT +  NK G+   +A + V+
Sbjct: 4938 LTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 10/137 (7%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYDFGY 2034
            E P F     + E   G  + LE  +    D  +R  W  +G  +  G H        G 
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGT 4953

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGE-------AVTTSSVKVDAKSGLYLDTLDEQRLKK 2087
             +L I      D G Y C+ +N  G+        V+ S  + ++ SG  LD    +  ++
Sbjct: 4954 CSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARR 5013

Query: 2088 IQELEKYERPKPIEEEQ 2104
            +  L + + P  + +E+
Sbjct: 5014 LHRLFRTKSPAEVSDEE 5030



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 1/58 (1%)

Query: 928 HFEARL-EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTC 984
           H EA+L   + D    V WLKDGR +    +     + G   L ++ V   DAG Y C
Sbjct: 721 HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/145 (20%), Positives = 59/145 (40%), Gaps = 11/145 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W      +    R + V    +  L +LG +  D+G Y C + +    A+++V +  V
Sbjct: 1839 VVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRV 1898

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             K       F + +  +   ++G  A F+C V P    D+ + W+ +G  ++ S +    
Sbjct: 1899 VK-------FMSGLSTVVA-EEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAIS 1947

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
                   L I+     D+G+    A
Sbjct: 1948 QSGASHSLTISDLVLEDAGQITVEA 1972



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 9/130 (6%)

Query: 448  HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            H L ++ +   DSG++  V + +   T+   RL V E    +   F      +   E E 
Sbjct: 2131 HTLTLSGLRPEDSGLM--VFKAEGVHTS--ARLVVTE----LPVSFSRPLQDVVTTEKEK 2182

Query: 508  VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            V L    +  P   + W KDGV +     + I   G   +L I R + +D   Y C A +
Sbjct: 2183 VTLECE-LSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHD 2241

Query: 568  VAGSTATRAR 577
               S + + +
Sbjct: 2242 AQSSASVKVQ 2251



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 43/206 (20%), Positives = 79/206 (38%), Gaps = 14/206 (6%)

Query: 370  YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE-VTWFIN 428
            Y       ET  R+ + +  L     K  +  +V EG+   F+C ++     +   W + 
Sbjct: 2716 YTCHVGSEETRARVRVHD--LHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVG 2773

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
             + +      +    +   + L++     SD+G V    R  + + +    L V E+   
Sbjct: 2774 GKTVGSSSRFQA-TRQGRKYILVVREAAPSDAGEVVFSVRGLTSKAS----LIVRERPAA 2828

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            +     +++    V  GE V L        TP + W KD   I  + +  +  +G  + L
Sbjct: 2829 IIKPLEDQW----VAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAML 2883

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTAT 574
             I  A   DA  Y C  +  + STA+
Sbjct: 2884 VIRGASLKDAGEYTCEVE-ASKSTAS 2908



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 5/92 (5%)

Query: 2108 RPV-FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            RPV F  AL  LE L EG  A   C +  +  P   + W +    +R G +Y    +   
Sbjct: 3183 RPVRFQEALKDLEVL-EGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAM 3238

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            + L +     +DSG Y C   ++   A  T T
Sbjct: 3239 LELVVRNLRPQDSGRYSCSFGDQTTSATLTVT 3270



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 6/109 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P +  +  +N + +EGA A  Q +L  N    V W K  + L + +++ +        L+
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQ 3594

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            +R    +D+G Y+ +     G   TS  L V +    + +  R++  T+
Sbjct: 3595 IRGLAMADTGEYSCVC----GQERTSAMLTVRALPIKFTEGLRNEEATE 3639



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 11/102 (10%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG--- 1911
            +LSEGQ A ++CR+        R  W   G  LQ+      + + G   L +LT++    
Sbjct: 4260 QLSEGQDASFQCRLSRASGQEAR--WALGGVPLQANEMNDITVEQG--TLHLLTLHKVTL 4315

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            ED+G  +     ++G   S  +L V +K +++R  ++  ALE
Sbjct: 4316 EDAGTVSF----HVGTCSSEAQLKVTAKNTVVRGLENVEALE 4353



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/105 (24%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            VPP  +   ++  V +G+ V L+ +V      +V W K  +++QP  R +++ + G   +
Sbjct: 4623 VPPQPS-APESRQVAAGEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQ-GRQQM 4679

Query: 4572 LILEAY-PQDSGKYEC-VAINSAGEARCDAECVVSLPATKDKPKP 4614
            L+++ +  +D G+Y C +A  S   A    +  +S  +  + P+P
Sbjct: 4680 LVIKGFTAEDQGEYHCGLAQGSICPAAATFQVALSPASVDEAPQP 4724



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG-HRYRTVYDMGFVS 3888
            P F         +  + +R EC V  K D  +R  W ++G  L  G H +      G  S
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCS 4955

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L I  +   D+G Y C+  N FG+
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQ 4979



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/86 (25%), Positives = 43/86 (50%), Gaps = 1/86 (1%)

Query: 4727 LRDIVVYEG-QPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
            LRD+ V  G + A+F+ ++     P + W ++G  +  +   +M  +     L I +   
Sbjct: 5266 LRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTR 5325

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            ED+G +    + A G   +SA+L+V+
Sbjct: 5326 EDSGQYAAYISNAMGAAYSSARLLVR 5351



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 10/151 (6%)

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPP--KFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            G+  E   E       D    +  VS P   KF++ + +   EE     F+C V P +  
Sbjct: 1869 GLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSD-- 1926

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             + + W+R+G LL    ++         SL I  +  ED+G+    A        + A +
Sbjct: 1927 -VAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAAL 1981

Query: 3920 SCKKLPDIILQNQVPRGM-KRSEALTQMEAT 3949
              ++ P +  +   P+ + +RS    ++E T
Sbjct: 1982 RVREAPVLFKKKLEPQTVEERSSVTLEVELT 2012



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 15/119 (12%)

Query: 751  EDYSKYQHQESIEEQTSQR-----PQFIRPLQDLGEL--QEGRNAHFEAQLTPVSDPTMR 803
            ED  +Y   ES ++ TS +     P+ ++ +  L  +  +EG  A F+  ++P SD  + 
Sbjct: 1873 EDAGEYVC-ESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP-SD--VA 1928

Query: 804  VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            V W++DG  +  S +     +    SL I  L  EDAG  TV A      A S+A++RV
Sbjct: 1929 VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAALRV 1983



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
            V +  P+  T  + +E K G+             A   V+WY ++ PL    +F  +   
Sbjct: 2463 VVSDIPVVLT--RPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEG 2520

Query: 1633 GFVALDIMSCLPEDSGTYTCRAINA 1657
                L I+  +P D+G Y C+A +A
Sbjct: 2521 QMAELRILRLMPADAGVYRCQAGSA 2545



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 772  FIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLN 831
            F++ L DL   + G  A  + +   VSDP   V W KDG  +  S +   +   G   L 
Sbjct: 2649 FLKALDDLSAEERGTLA-LQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV 2704

Query: 832  IMHLRAEDAGSYT 844
            +  +  EDAG YT
Sbjct: 2705 VHDVSPEDAGLYT 2717



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 8/119 (6%)

Query: 2883 GLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPD 2942
            GL  V+ AE + +    R S   T  P P   I      + +EG    L  ++  K  P 
Sbjct: 3333 GLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELS-KAAP- 3390

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
              +EW    + L  G R  L  D     L +  +   D+G Y+C      GE  TS+T+
Sbjct: 3391 --VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVC----GEERTSATL 3443



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 9/101 (8%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV   P +F+  L N E VEG    L C L  V      VEW    + ++ G R+    
Sbjct: 3443 LTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAP----VEWRKGPENLRDGDRYILRQ 3498

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            E     L +  +   D+G Y C      G+  TS  L + A
Sbjct: 3499 EGTRCELQICGLAMADAGEYLCVC----GQERTSATLTIRA 3535



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 2373 RQRPV-FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431
            R  P+ FT+ L+N +   EG TA   C L  +      VEW++  + + D  R +   D 
Sbjct: 3622 RALPIKFTEGLRN-EEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDG 3676

Query: 2432 GYVSMTISHVRDEDEGVYMC 2451
                + I  +  ED G Y+C
Sbjct: 3677 ARCELQIRGLVAEDAGEYLC 3696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
            +F + ++N E TEG    L   L+ +      VEW+     ++ G R     D     L 
Sbjct: 3627 KFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQ 3682

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL 2080
            I    AED G Y+C      G+  T++ + V A    +++ L
Sbjct: 3683 IRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGL 3720



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 90/376 (23%), Positives = 143/376 (38%), Gaps = 34/376 (9%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV  AP +F R L + E  EG   HL C L   G     VEW      +    +++   
Sbjct: 3972 LTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAG---ASVEWRKGSLQLFPCAKYQMVQ 4028

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK-DLILES--QHPSGLEK 1420
            +     L +  V  ED+G YTC   +   +++ S ++RV   K    L+S  Q    + +
Sbjct: 4029 DGAAAELLVRGVEQEDAGDYTCDTGHT--QSMASLSVRVPRPKFKTRLQSLEQETGDIAR 4086

Query: 1421 I-QYLEDTSRYKKTDIIDESVTIK--PRFVTRPKSI--ENVIEGQHVHFECKLEPVTDSN 1475
            +   L D         + E V +   P++  R +    E +I         +   VT   
Sbjct: 4087 LCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQ 4146

Query: 1476 LKVEWFKNGQP-VTIGHRFRPIHDFGYVALDIIDLIAEDS-----GIYTC-RAVNLVGTD 1528
                  +  +P VTI    R + D    A + ++   E S     G+  C + + L   +
Sbjct: 4147 KTAASLRVTEPEVTI---VRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNE 4203

Query: 1529 --EVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKN 1586
              EV+ R     T  +   T  +AG     +    S    T    EVT   P     L++
Sbjct: 4204 VTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEP-----LQD 4258

Query: 1587 VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV-ALDIMSCLPE 1645
            V++ EGQ A F+ RL   S    +  W     PL++      T   G +  L +     E
Sbjct: 4259 VQLSEGQDASFQCRLSRASGQ--EARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLE 4316

Query: 1646 DSGTYTCRAINALGEA 1661
            D+GT +        EA
Sbjct: 4317 DAGTVSFHVGTCSSEA 4332



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 13/134 (9%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            +++   VF + L++   ++EG+++ L C       P   V W  +G+++   +R +  ++
Sbjct: 3091 VTEKPSVFSRELTDAT-ITEGEDLTLVCETSTCDIP---VCWTKDGKTLRGSARCQLSHE 3146

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL 1291
                 L I  AT  D+G Y   A    G A +S+IVRV  R       + ++A++ +++L
Sbjct: 3147 GHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRVHAR-----PVRFQEALKDLEVL 3197

Query: 1292 EDAARRTKQVREDI 1305
            E  A   + V   +
Sbjct: 3198 EGGAATLRCVLSSV 3211



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 8/126 (6%)

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRR-----EDVEVAVNQAPRFITQLNGP 1853
            TL   ++  L  E      L     L+DS RY+           V V+  P    +    
Sbjct: 3134 TLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
             ++ EG +A   C +     P   V+W +   VL+ G +Y    +     L +  +  +D
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQD 3250

Query: 1914 SGEYTC 1919
            SG Y+C
Sbjct: 3251 SGRYSC 3256



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W KDG+ + +SS++          L ++ V   DAG Y+C A    G    S  L I 
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSFQLHIT 1252

Query: 1003 TKKDIIAESQ 1012
              K + A+ Q
Sbjct: 1253 EPKAVFAKEQ 1262



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 2011 VEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            V+WY +  P+    +FK + +     L IL     D G Y C+A    G A +++ V V+
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 2071 AK 2072
            A+
Sbjct: 2555 AR 2556



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/140 (24%), Positives = 60/140 (42%), Gaps = 9/140 (6%)

Query: 2197 CTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256
            C L   GHR  +L T          + EA G  +   +      P RF   L+    V E
Sbjct: 3141 CQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSS-SIVRVHARPVRFQEALKDL-EVLE 3198

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            G  A   C +  V  P   +++ +    L+   ++ +  +   + L +++  P+D+G YS
Sbjct: 3199 GGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255

Query: 2317 VKAINALGHCTSAISMTVTA 2336
                 + G  T++ ++TVTA
Sbjct: 3256 C----SFGDQTTSATLTVTA 3271



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 7/97 (7%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P +F   +K   V E       C +     P   ++W     +L  G +Y    +   + 
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLE 3240

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L +  +  +DSG Y C     FG+  T AT++   LP
Sbjct: 3241 LVVRNLRPQDSGRYSC----SFGDQTTSATLTVTALP 3273



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 38/172 (22%), Positives = 68/172 (39%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +++    R        +  L+I G    D+G YSC    +   A ++V     
Sbjct: 3391 VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTV----- 3445

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
               K    +FT  ++N E + +G +A   C +  V      +EW    + +R   R    
Sbjct: 3446 ---KALPAKFTEGLRNEEAV-EGATAMLWCELSKV----APVEWRKGPENLRDGDRYILR 3497

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             +     L I      D+GEY+C      G++ T AT+        ++E ++
Sbjct: 3498 QEGTRCELQICGLAMADAGEYLCVC----GQERTSATLTIRALPARFIEDVK 3545



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 6/105 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P K  +  RN +  EG  A    +LS    P V W K  + L + ++H +    +   L+
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS-KAAP-VEWRKGHETLRDGDRHSLRQDGSRCELQ 3770

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
            +R     D+G Y+ +     G   TS  L V +    +++D ++Q
Sbjct: 3771 IRGLAVVDAGEYSCVC----GQERTSATLTVRALPARFIEDVKNQ 3811



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 6/96 (6%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG +A  +C +    +P   V W   G  LQ+  R         A L +  +  ED+GEY
Sbjct: 3903 EGSTATLQCELS---EPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            TC   +   QA S+      +    +R+ QH+   E
Sbjct: 3960 TCTCGS---QATSATLTVTAAPVRFLRELQHQEVDE 3992



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 8/119 (6%)

Query: 2087 KIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWF 2146
            KIQ   K  + +   ++Q G  P+F       E  + GD    EC V    D  +   W 
Sbjct: 4878 KIQAAFKGYKVRKEMKQQEG--PMFSHTFGDTE-AQVGDALRLECVVASKAD--VRARWL 4932

Query: 2147 HNGQKIRAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKATNKLGEAVNTCTLKVAG 2203
             +G ++  G R+      G     +L T  +  D+G Y C+ +NK G+  ++  + V+G
Sbjct: 4933 KDGVELTDG-RHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSG 4990



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P   PP F  EL   T    G+T    C+V     P   I +Y +GKA+Q      +  D
Sbjct: 6009 PVWRPPDFEEELADCTAEL-GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIED 6065

Query: 2297 -FGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              G  +L +      D+G+Y   A +A G+C++
Sbjct: 6066 PDGSCALILDSLTGVDSGQYMCFAASAAGNCST 6098



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 3/113 (2%)

Query: 1035 EEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT 1094
            ++ + +  PRFL   K     V G+ A    ++    + T  V W  + + + +  R + 
Sbjct: 2    DQPQFSGAPRFLTRPKAFVVSV-GKDATLSCQIV--GNPTPQVSWEKDQQPVAAGARFRL 58

Query: 1095 YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIH 1147
              D     L I  +   DSG Y   ARNA GEA  +  + V+  ++    + H
Sbjct: 59   AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C +     P   V WY +GK L S  + R         L +  V   D+GEY+
Sbjct: 1181 GTTAMLSCEVA---QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            C+A    GQ V S +L++   +++    Q
Sbjct: 1238 CEA---GGQRV-SFQLHITEPKAVFAKEQ 1262



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 12/145 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  I  S R  T        L + G +  DS  YSCR   + GQ +  V++E V
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAE-GQ-DFPVQVEEV 1807

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                    +F   ++ + G + G +    C + P      ++ W      +R   R + V
Sbjct: 1808 ------AAKFCRLLEPVCG-ELGGTVTLACELSPA---CAEVVWRCGNTQLRVGKRFQMV 1857

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            ++     L +   +  D+GEYVC +
Sbjct: 1858 AEGPVRSLTVLGLRAEDAGEYVCES 1882



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 1024 EDASRY---SKRTEEEVKITQK-PRFLGPLKGTNKIV--EGQSAHFEARVEPQSDLTMTV 1077
            EDA  Y   S+      ++T   PR +  + G + +V  EG  A F+  V P SD+   V
Sbjct: 1873 EDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP-SDVA--V 1929

Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL 1129
             W+ +G  +  + +          +L I+ +  ED+G  TV A  A+  A L
Sbjct: 1930 VWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAAL 1981



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 4/62 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            ++W+K+   L+   + K + +  +  L I  L   D+G+Y C+A    G A S+  + +E
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 2736 DR 2737
             R
Sbjct: 2555 AR 2556



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF+  L+++  +E   +  +C V    DP   + W  +   L    +Y   H      L 
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEVS---DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV 2704

Query: 2835 ITHTYEEDSGIYTC 2848
            +     ED+G+YTC
Sbjct: 2705 VHDVSPEDAGLYTC 2718



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/49 (34%), Positives = 23/49 (46%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583
            V DP     W  +GV+L    ++   H  G   L ++ V   DAGLY C
Sbjct: 2670 VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC 2718



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 8/114 (7%)

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
            K T+    + KA  FT  L+N++ + E   A F  +   T+ P   V W      L+A  
Sbjct: 2904 KSTASLHVEEKANCFTEELTNLQ-VEEKGTAVFTCK---TEHPAATVTWRKGLLELRASG 2959

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            + +   +   + L IS     DS  Y C    + G+A + A + VQG+R  I+E
Sbjct: 2960 KHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLVQGRRVHIIE 3009



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 13/119 (10%)

Query: 1439 SVTIKP---RFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            S+TI+P    F+ R +  E+ IEG      C+L         VEW K  + +  G R   
Sbjct: 3354 SLTIRPMPAHFIGRLRHQES-IEGATATLRCELSKAAP----VEWRKGRESLRDGDRHSL 3408

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLE 1553
              D     L I  L   D+G Y+C    + G +  S  LT ++         +NE  +E
Sbjct: 3409 RQDGAVCELQICGLAVADAGEYSC----VCGEERTSATLTVKALPAKFTEGLRNEEAVE 3463



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + + P KF   +++    E       C +  K  P   +EW +  + L  G RY    + 
Sbjct: 3445 VKALPAKFTEGLRNEEAVEGATAMLWCELS-KVAP---VEWRKGPENLRDGDRYILRQEG 3500

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+GEY+C      G++ T AT++ + LP
Sbjct: 3501 TRCELQICGLAMADAGEYLCVC----GQERTSATLTIRALP 3537



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/90 (24%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P+F   L+S  +  EG    L+ ++   ++P   + W K G+ L    R +         
Sbjct: 3890 PVFREPLQSL-QAEEGSTATLQCEL---SEPTATVVWSKGGLQLQANGRREPRLQGCTAE 3945

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            L +  L+ +D+G YTC   +    A  T +
Sbjct: 3946 LVLQDLQREDTGEYTCTCGSQATSATLTVT 3975



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTC 4793
            G   + +  + SK     +WL++G  + +     +   G+    LLI      D G +TC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971

Query: 4794 RATTAAGQVETSAKLVV 4810
            + +   GQV  SA +VV
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 5/77 (6%)

Query: 3576 HFECRLIP-VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
            H E +L+  ++D +  V W  +G+ L  G + +     G  +L +  V + DAGLY C  
Sbjct: 721  HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC-- 778

Query: 3635 TNRHGEATVSCKLQVKG 3651
             +R G   ++ +L V+G
Sbjct: 779  VSRGGR--IAYQLSVQG 793



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 13/45 (28%), Positives = 21/45 (46%)

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
           +TW KDG  + P P+  +    G   L +      DA  Y+C ++
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSR 781



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 16/51 (31%), Positives = 26/51 (50%)

Query: 797  VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
            V+ P   V WYKDG+ +++SS++          L +  +   DAG Y+  A
Sbjct: 1190 VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 4/77 (5%)

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            +  +   V W KDG+ + +SS++          L ++     DAG YTC A    G    
Sbjct: 1282 VAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRL 1337

Query: 996  SANLTIVTKKDIIAESQ 1012
            S +L +   K + A+ Q
Sbjct: 1338 SFHLDVSEPKAVFAKEQ 1354



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 3/76 (3%)

Query: 1992 GHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYM 2051
            G  V L   L+P       V W C    ++ G RF+   +    +L +L   AED G Y+
Sbjct: 1823 GGTVTLACELSPA---CAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYV 1879

Query: 2052 CKATNAVGEAVTTSSV 2067
            C++ +    A  T SV
Sbjct: 1880 CESRDDHTSAQLTVSV 1895



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/94 (26%), Positives = 36/94 (38%), Gaps = 7/94 (7%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            KP       D +S +E G    +     + D    V W KDG  +  S +       G  
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTR 2701

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L +  V+  DAG YTC     +G   T A + +
Sbjct: 2702 GLVVHDVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 7/87 (8%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            GE+      L+    P   V W  + K+++   ++   C+    +L I     +D+GEY 
Sbjct: 2841 GEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897

Query: 3495 CRAYNNYGEAVTTASMKVQGKRNIILE 3521
            C        + +TAS+ V+ K N   E
Sbjct: 2898 CEV----EASKSTASLHVEEKANCFTE 2920



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 42/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F +  +D +V EG      C ++    P V W   +  +R    +  L  E     L++
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYS-LRQEGAMLELVV 3243

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             N+   DSG  +C      G+      L V      +  +F+ +       EG    L  
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVT----ALPAQFIGKLRNKEATEGATATLRC 3295

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
              +    P + W+K    +       +  DG    L I      DAA Y C    V G  
Sbjct: 3296 E-LSKAAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC----VCGEE 3349

Query: 573  ATRARL 578
             T A L
Sbjct: 3350 RTSASL 3355



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG      C +     P   ++W + N  L  G +Y    + + + L +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVV 3243

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
             +   +DSG Y+C    S G  TTS +L  T
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVT 3270



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P  F +  KN    +G  A  + +L  N    V W +    L + ++YS+R  +      
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLR--QDGTKCE 3592

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163
            L I+ +   D GEY+C    +   A+ +V   P
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALP 3625



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 4/83 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  + N   +EG     +C +  +      +EW   ++ L  G RY    D +   L I
Sbjct: 3804 FIEDVKNQEAREGATAVLQCELSKAAP----VEWRKGSETLRGGDRYSLRQDGTRCELQI 3859

Query: 2836 THTYEEDSGIYTCKATNSKGSAT 2858
                  D+G Y+C     + SAT
Sbjct: 3860 HGLSVADTGEYSCVCGQERTSAT 3882



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 9/102 (8%)

Query: 1690 QLEDTSKY-----QRHSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLR 1743
            Q EDT +Y      + ++    +T APV F   ++   V E   AH    L   G     
Sbjct: 3952 QREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAG---AS 4008

Query: 1744 VEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785
            VEW +  + +    +   + D     L ++ V  ED+G YTC
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC 4050



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG-HR 1358
            Q R  + V + P F   L +     G  V L CR+   G     + W+ +GK ++   H 
Sbjct: 6003 QQRLALPVWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHH 6060

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                      AL L S+   DSG Y C A +  G   T
Sbjct: 6061 ILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCST 6098



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 943  VEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+ V+     I      G  AL + S+T  D+G Y C A +A G  +T   + +
Sbjct: 6045 ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104


>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
           calmodulin and titin-interacting RhoGEF protein.
          Length = 6620

 Score =  124 bits (300), Expect = 6e-27
 Identities = 89/325 (27%), Positives = 141/325 (43%), Gaps = 14/325 (4%)

Query: 245 VGESDVQISTEIDRSLGPVSP-PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
           +GE+   +  ++D         P    +P + +++EG++A F+ ++ G+PRP V+W K+G
Sbjct: 88  IGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDG 147

Query: 304 QRLINSNKHEIITTH--NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP--- 358
           +RL   +   +        + LR+R  +  D G Y + AENP G    +  L V+S    
Sbjct: 148 RRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD 207

Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
           T S      +  +   Q+R    R E +  +      + C    VTEGK  R  C VTG 
Sbjct: 208 TASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCT---VTEGKHARLSCYVTGE 264

Query: 419 PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
           P PE  W  + + + +   H +  +   N  L I     SD G+ TC A N  G+T +  
Sbjct: 265 PKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT-YSS 323

Query: 479 RLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
            L V+ +  V    F +R   L VRE E        V  P+    W K+   +  + +  
Sbjct: 324 VLVVVREPAV---PFKKRLQDLEVREKESATFLCE-VPQPSTEAAWFKEETRLWASAKYG 379

Query: 539 IHTDGGASTLDIPRAKASDAAWYQC 563
           I  +G    L +    A D A Y C
Sbjct: 380 IEEEGTERRLTVRNVSADDDAVYIC 404



 Score =  122 bits (293), Expect = 4e-26
 Identities = 100/341 (29%), Positives = 149/341 (43%), Gaps = 44/341 (12%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLL 4572
            P F    QN  V  G  V  D  VTG     V W K+GK ++ D    I E+  G + L+
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK-DKPKPQTKAAN----------- 4620
            I    P D G Y C+A NS G +   AE  V L +T  D     T++++           
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245

Query: 4621 ------------APPEIIEPLKDKIVAEGQAI-EFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                          P+++E L+D  VA G  + +F  K+ G P P + W+K  + +  S 
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA---- 4723
            + +M+     +TL I     ED G Y     N+ G    +A+L V  PD+ +  PA    
Sbjct: 5306 HIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVH 5365

Query: 4724 --LTPLRDI------VVYEGQPAQFKTQITSKIKPTIQWLREGA------LIPETPDFQM 4769
              L P R +       V +G    F  ++  +  PT+ WLRE A      + P+TP + +
Sbjct: 5366 EQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV 5425

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                    L++ +   +  GT+TC A+ AAGQ   SA L V
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score =  103 bits (248), Expect = 1e-20
 Identities = 92/342 (26%), Positives = 141/342 (41%), Gaps = 30/342 (8%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--TL 323
            P    + +N ++Q+G    F   ++G P P V WFK+G +L+  + H +I         L
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDG-KLLEEDDHYMINEDQQGGHQL 5184

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY--VQD--QRSQYITDT---QQ 376
             +     +D G Y  LAEN  G   T   L V+  +  Y    D  + S Y +       
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244

Query: 377  RETEERIEISEKALAPQFVKVCQDRDVTEG-KMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            RE E     +++   PQ V+  +D  V  G ++ +F  +V G P P + WF  D Q    
Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF-KDGQPLTA 5303

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI------EK---- 485
              H  + ++   H L I +VT  DSG       N  G      RL V       EK    
Sbjct: 5304 SAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASD 5363

Query: 486  --EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPII--PNPEL 537
              EQ+V P+ +ERF+   V++G  +  + +  G P P + W ++    GV  I    P  
Sbjct: 5364 VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423

Query: 538  RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             + +     +L +          Y C A N AG     A L+
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLH 5465



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 103/424 (24%), Positives = 163/424 (38%), Gaps = 31/424 (7%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            S  P F  + +   V   + A    +  G P P + W ++  P+     F++        
Sbjct: 7    SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I  + + DS  +   A N  G A  +  L V+ +          P F L   ++ V  
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA---PHFLLRPTSIRVRE 123

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKV-QPDIRNKILEEDGTYTLL-ILEAYPQDSGKYE 4585
            G       +V G+    V W K+G+++ +PD     +EE G  + L I  A P+D G YE
Sbjct: 124  GSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYE 183

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQT----------------KAANAPPEIIEP- 4628
              A N  G A   A  VV   A     +P T                +A  AP       
Sbjct: 184  VRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTG 243

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-YTLRISEAFP 4687
             +   V EG+    SC + G+P P   W K  +L+   +   +   A E + L+I     
Sbjct: 244  TRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ 303

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
             D G Y C A N  G+   +  + V +P     +P    L+D+ V E + A F  ++   
Sbjct: 304  SDRGLYTCTASNLVGQTYSSVLVVVREP----AVPFKKRLQDLEVREKESATFLCEVPQP 359

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
                  W +E   +  +  + +  EG    L + N   +D   + C   T  G   T A+
Sbjct: 360  -STEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE--TPEGS-RTVAE 415

Query: 4808 LVVK 4811
            L V+
Sbjct: 416  LAVQ 419



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 87/334 (26%), Positives = 132/334 (39%), Gaps = 30/334 (8%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP+F+   +   V+ GK     C++ G P P+V+W  + + +      + L  +   + L
Sbjct: 9   APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFR-LAQDGDLYRL 67

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVERFSTLNVREGEPV 508
            I ++ L DSG   C ARN  GE      L V  +      AP F+ R +++ VREG   
Sbjct: 68  TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEA 127

Query: 509 VLNARAVGTPTPRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
               R  G+P P ++W KDG  +     P +R+   G AS L I  A+  D   Y+  A+
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187

Query: 567 NVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIP 626
           N  G+ +  A L                  RP                L H++R R  + 
Sbjct: 188 NPLGAASAAAALVVDSDAADTAS-------RP---------GTSTAALLAHLQRRREAM- 230

Query: 627 PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686
              E     PP      ++ T  EG   H        G+P  +  W K+GQ +    R  
Sbjct: 231 -RAEGAPASPPS--TGTRTCTVTEGK--HARLSCYVTGEPKPETVWKKDGQLVTEGRRHV 285

Query: 687 SIFRFGY--ISLDMLSLNIQDSGEYTCRAVSATG 718
            ++        L +L     D G YTC A +  G
Sbjct: 286 -VYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 8/194 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP+  E L D     G+ ++ +C++ G P P + WYK  K ++   +  +    D     
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 4682 ISEAFPE-DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I ++    D G Y C A ++AG  +   K+ V  P +  N    +P       EG+ AQF
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPF-----VEGEDAQF 6127

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRATTA 4798
               I     P I+W ++GAL+     FQ + E  +   VL+I    +ED G + C     
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187

Query: 4799 AGQVETSAKLVVKS 4812
             G    SA+L ++S
Sbjct: 6188 LGSARASAELRIQS 6201



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 57/208 (27%), Positives = 103/208 (49%), Gaps = 8/208 (3%)

Query: 4514 PSFTLTAQNVNVTSG-QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            P      +++ V  G +L +   KV G     +YW K+G+ +      ++ ++   +TL 
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLP-ATKDKPKPQTKAANAPPEIIEPLKD 4631
            I+    +DSG+Y     N+ G A   A  +V  P   ++KP         PP ++E    
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTP 5379

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWY-----KGDKLIKP-SKYFQMSRTADEYTLRISEA 4685
            K V +G +I FS K+ G+P+PTV W      +G   I P +  + ++ +A +++L + + 
Sbjct: 5380 KKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDV 5439

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
              + +G Y C+A N+AG+   +A L V+
Sbjct: 5440 GRQHQGTYTCIASNAAGQALCSASLHVS 5467



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIRNKILEE-DGTYT 4570
            PP F     +     G+ V+L  +VTGT KP+ + W K+GK VQ D  + ++E+ DG+  
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPV-ISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L++      DSG+Y C A ++AG      + +V +P                P  +  ++
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP----------------PRFVNKVR 6115

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--MSRTADEYTLRISEAFPE 4688
                 EG+  +F+C I G P P ++WYK   L+     FQ      +    L I  A  E
Sbjct: 6116 ASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKE 6175

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            D G Y+C   N  G    +A+L++  P
Sbjct: 6176 DLGLYECELVNRLGSARASAELRIQSP 6202



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/230 (29%), Positives = 107/230 (46%), Gaps = 9/230 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT-SIFRFGYIS 695
            P F+  L++    +G  + F+  +   G P   + W K+G+ +E    +  +  + G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT-IERTSQHPETLQYIQQLEDYS 754
            L + ++   D G Y C A ++ GV+ TKA L V   +T  +  +   E+  Y    + Y 
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA-QGYL 5242

Query: 755  KYQHQESIEEQTS--QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
              + QE  E  T   Q PQ +  L+DL      R A F  QL     P  R+ W+KDG+P
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKF--QLKVKGYPAPRLYWFKDGQP 5300

Query: 813  ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +TAS+ I         +L I+ +  ED+G Y     N +G A S+A + V
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 60/202 (29%), Positives = 92/202 (45%), Gaps = 5/202 (2%)

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
            Q + + AP  +  P K  +V+ G+    SC+IVG P P V W K  + +     F++++ 
Sbjct: 3    QPQFSGAPRFLTRP-KAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNLP-ALTPLRDIVV 4732
             D Y L I +    D G Y C A N+ G    A  L+V  +   A+  P  L     I V
Sbjct: 62   GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRV 121

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALI--PETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             EG  A F+ ++    +P + W ++G  +  P+ P  ++   G  + L I      D GT
Sbjct: 122  REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181

Query: 4791 FTCRATTAAGQVETSAKLVVKS 4812
            +  RA    G    +A LVV S
Sbjct: 182  YEVRAENPLGAASAAAALVVDS 203



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 92/364 (25%), Positives = 153/364 (42%), Gaps = 26/364 (7%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYV 1768
            APVF   +++  V +     F+   +  G P   V W ++G  +E  +      D  G  
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQ--LESQHESALQKIQQLED 1826
             L +  V P D G Y C A N +G + T + L V   ++         ES+     Q   
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
            SSR Q   +      Q P+ + +L         + A ++ +++ YP P  R+ W+ +G+ 
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYWFKDGQP 5300

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946
            L +    R ++      L+I++V  EDSG+Y     N +G A SS RL V+  +    + 
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD----EP 5356

Query: 1947 QHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND 2006
            + + A +  + L      +R      F  +K + G  I  +   EG PV     L    +
Sbjct: 5357 EEKPASDVHEQLVPPRMLER------FTPKKVKKGSSITFSVKVEGRPVPTVHWLR--EE 5408

Query: 2007 PTMRVEWYCNGRPVQQGHRF-KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
                V W     P   G+    +      V LD+     +  GTY C A+NA G+A+ ++
Sbjct: 5409 AERGVLWI---GPDTPGYTVASSAQQHSLVLLDV---GRQHQGTYTCIASNAAGQALCSA 5462

Query: 2066 SVKV 2069
            S+ V
Sbjct: 5463 SLHV 5466



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F +   D     G+  +  CRVTG P P ++W+ + + ++ D +H ++ +  G+ AL+
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            + ++T  DSG   C A + +G  +   ++ V      V P+FV +       EGE     
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFT 6128

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVA 569
                G P P+I W KDG  +    + +  ++   G   L I  A   D   Y+C   N  
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188

Query: 570  GSTATRARL 578
            GS    A L
Sbjct: 6189 GSARASAEL 6197



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 61/258 (23%), Positives = 111/258 (43%), Gaps = 22/258 (8%)

Query: 266  PKIAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P++ ++ R+ ++  G   A+FQ+++ G P PR+ WFK+GQ L  S    +       TL 
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            + +  + DSG Y     N  G   +S  L V  P E                 E +   +
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEP----------------EEKPASD 5363

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-----IRDDYNHK 439
            + E+ + P+ ++    + V +G    F  +V GRP P V W   + +     I  D    
Sbjct: 5364 VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423

Query: 440  ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
             + + +  H+L++ +V     G  TC+A N +G+      L+V    +V   + V+    
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 5483

Query: 500  LNVREGEPVVLNARAVGT 517
                +G    ++A+ + T
Sbjct: 5484 STFLQGTTQAISAQGLET 5501



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 90/406 (22%), Positives = 162/406 (39%), Gaps = 48/406 (11%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T  +Q     E   A F  E   E    ++W     P+ N    +I     +  L+++ +
Sbjct: 2561 TGPLQDAEATEEGWASFSCELSHEDEE-VEWSLNGMPLYNDSFHEISHKGRRHTLVLKSI 2619

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
               D+ +       R  + K S +  +E +       + P  F     +++      + L
Sbjct: 2620 QRADAGIV------RASSLKVSTSARLEVR-------VKPVVFLKALDDLSAEERGTLAL 2666

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              +V+  +   V W K+G ++ P  +   L   GT  L++ +  P+D+G Y C   +   
Sbjct: 2667 QCEVSDPEA-HVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEET 2725

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR                    +  +    I + LK   V EG++  F C +  +    
Sbjct: 2726 RAR-------------------VRVHDLHVGITKRLKTMEVLEGESCSFECVLSHESASD 2766

Query: 4654 -VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
               W  G K +  S  FQ +R   +Y L + EA P D G+   V ++  G +T  A L V
Sbjct: 2767 PAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGE---VVFSVRG-LTSKASLIV 2822

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
             +   A     + PL D  V  G+  + + +++    P + WL++   I ++  + ++ E
Sbjct: 2823 RERPAA----IIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCE 2877

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRA----TTAAGQVETSAKLVVKSKT 4814
            G  A+L+I     +D G +TC      +TA+  VE  A    +  T
Sbjct: 2878 GTMAMLVIRGASLKDAGEYTCEVEASKSTASLHVEEKANCFTEELT 2923



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 9/231 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYVA 2036
            P F   ++N EV +G+PV  +  +T    P   V W+ +G+ +++   +    D  G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096
            L I      D G Y C A N++G + T + ++VD  S  Y    D          + Y  
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243

Query: 2097 PKPIEEEQP----GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
             +  E  +     GQ P  +  L  L+       A F+ +V+    P L   WF +GQ +
Sbjct: 5244 SREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLY--WFKDGQPL 5301

Query: 2153 RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
             A    R T       L+I+    EDSG Y    +N +G A ++  L V G
Sbjct: 5302 TASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 100/393 (25%), Positives = 157/393 (39%), Gaps = 53/393 (13%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSILIIRQVFVEDSAV 4480
            V E   A F           + W+ +  P+  +   +I        +L +RQ+ ++DS  
Sbjct: 3016 VQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGT 3075

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
                A    G  + SA L V EK         P  F+    +  +T G+ + L  + T T
Sbjct: 3076 IYFEA----GDQRASAALRVTEK---------PSVFSRELTDATITEGEDLTLVCE-TST 3121

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
              I V W K+GK ++   R ++  E     LLI  A  QDSG+Y+C     AG A C + 
Sbjct: 3122 CDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC----EAGGA-CSSS 3176

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             V              +    P    E LKD  V EG A    C +     P V+W  G+
Sbjct: 3177 IV--------------RVHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGN 3221

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
             +++P   + + +      L +    P+D G Y C    S G  T +A L VT       
Sbjct: 3222 NVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTA------ 3271

Query: 4721 LPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778
            LPA  +  LR+    EG  A  + ++ SK  P ++W +    + +   + +  +G    L
Sbjct: 3272 LPAQFIGKLRNKEATEGATATLRCEL-SKAAP-VEWRKGSETLRDGDRYCLRQDGAMCEL 3329

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             I      D   ++C      G+  TSA L ++
Sbjct: 3330 QIRGLAMVDAAEYSC----VCGEERTSASLTIR 3358



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 106/440 (24%), Positives = 180/440 (40%), Gaps = 56/440 (12%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            I R++ + +  EI+  A+  E   +  VK   P    + ++     E  +   E +    
Sbjct: 2258 IYRRVLAEDAGEIQFVAENAESRAQLRVK-ELPVTLVRPLRDKIAMEKHRGVLECQVSRA 2316

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
                ++W++ +  ++  P +++ +      LII  V  ED   +   A    G  K SA 
Sbjct: 2317 SAQ-VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQ 2371

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVT--SGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              VEE+      G+         Q+V V   +      +T +   +P    WL  GK V 
Sbjct: 2372 FFVEEQSITIVRGL---------QDVTVMEPAPAWFECETSIPSVRPPK--WLL-GKTVL 2419

Query: 4556 PDIRNKILEEDGT-YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                N  LE++GT + L++       +G        + G++R  A  VVS          
Sbjct: 2420 QAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHF----TVGKSRSSARLVVS---------- 2465

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSR 4673
                 + P  +  PL+ K   E Q++  SC    +P P  VQWYK D  + PS+ F+MS 
Sbjct: 2466 -----DIPVVLTRPLEPKTGRELQSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSL 2518

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  LRI    P D G Y+C     AG    + ++ V    +A  +    PL+D    
Sbjct: 2519 EGQMAELRILRLMPADAGVYRC----QAGSAHSSTEVTV----EAREVTVTGPLQDAEAT 2570

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            E   A F  +++ +    ++W   G  +      ++ H+G    L++ +    D G    
Sbjct: 2571 EEGWASFSCELSHE-DEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG--IV 2627

Query: 4794 RATTAAGQVETSAKLVVKSK 4813
            RA++   +V TSA+L V+ K
Sbjct: 2628 RASSL--KVSTSARLEVRVK 2645



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 69/232 (29%), Positives = 99/232 (42%), Gaps = 13/232 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI-EASNRLTTMHDFGY 1767
            QAP F +    IRV E   A F  R+   G P+  V W ++G  + E       + + G 
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRV--GGSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165

Query: 1768 V-ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLED 1826
              AL ++   P D GTY  RA N LG A  ++ L V S A+        S    +  L+ 
Sbjct: 166  ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ- 224

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                +RRE +      A    T     T ++EG+ A   C +   P P     W  +G++
Sbjct: 225  ----RRREAMRAEGAPASPPSTGTRTCT-VTEGKHARLSCYVTGEPKP--ETVWKKDGQL 277

Query: 1887 LQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            +  G R+    D      L IL     D G YTC A N +GQ  SS+ + V+
Sbjct: 278  VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 92/386 (23%), Positives = 153/386 (39%), Gaps = 38/386 (9%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-TETNNFGFV 1635
            AP+  T L+N E+++G    F+   +        V W+ + K L+    +    +  G  
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFD--CVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY----LESQHEGALPRLNQL 1691
             L I + +P D G Y C A N++G + T     V    + Y      ++          L
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAE-NQAAHFEARLIPVGDPKLRVEWLRNG 1750
                +    S  DE   Q P     ++D++VA   + A F+ ++   G P  R+ W ++G
Sbjct: 5243 SSREQEGTESTTDE--GQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKDG 5298

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             P+ AS  +          L +  V  EDSG Y     N +G A +S+ L V+       
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD---- 5354

Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870
            E + + A    +QL                   PR + +   P K+ +G S  +  ++E 
Sbjct: 5355 EPEEKPASDVHEQL-----------------VPPRMLERFT-PKKVKKGSSITFSVKVEG 5396

Query: 1871 YPDPNMR-VEWYFNGKVLQSG---HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             P P +  +       VL  G     Y  ++     +L +L V  +  G YTC A N  G
Sbjct: 5397 RPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG 5456

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESAL 1952
            QA+ S  L+V     +    + + AL
Sbjct: 5457 QALCSASLHVSGLPKVEEQEKVKEAL 5482



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 84/325 (25%), Positives = 133/325 (40%), Gaps = 22/325 (6%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F T  K  V +S G+ A     ++  G+ +  + W  + + + A  R R      +  
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQIV--GNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKG---QKPRFTTHIQNIEGLKDG 3164
            L IL     DSG Y CRA N  G+A  +V L+ VD       Q P F     +I  +++G
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQ-VDAEAACAEQAPHFLLRPTSIR-VREG 124

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRH--STRIKTVSDFGFV-VLDIAYTQNHDSGE 3221
              A F C V     P   + W  +G+ +      R++ V + G    L I   +  D G 
Sbjct: 125  SEATFRCRV--GGSPRPAVSWSKDGRRLGEPDGPRVR-VEELGEASALRIRAARPRDGGT 181

Query: 3222 YVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            Y  RA N  G     A +                + A +  L+  + A  +    P A P
Sbjct: 182  YEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA-MRAEGAP-ASP 239

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIV 3340
            P   T+   VT   EG+ A     +    +P  +  W  +G+ +  G R+  + D     
Sbjct: 240  PSTGTRTCTVT---EGKHARLSCYV--TGEPKPETVWKKDGQLVTEGRRHVVYEDAQENF 294

Query: 3341 ILDILYCYEENSGEYECVATNKLGR 3365
            +L IL+C + + G Y C A+N +G+
Sbjct: 295  VLKILFCKQSDRGLYTCTASNLVGQ 319



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 63/233 (27%), Positives = 101/233 (43%), Gaps = 7/233 (3%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S + PVF+  L N   V +G  +  +C +   G P   V WF +G+ +     +    D 
Sbjct: 5122 SDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQL 1290
             G   L I     AD G Y   A N +G + T A +RV +  +D  T     ++      
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238

Query: 1291 LEDAARRTKQVREDITVM-QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN 1349
                + R ++  E  T   Q PQ    L +++   GT +  + +L+  G    R+ WF +
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFKD 5297

Query: 1350 GKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            G+P+      R   +     L+++SV  EDSG Y    +N +G A +S  L V
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 34/92 (36%), Positives = 54/92 (58%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F+   Q+++V +G    FDC VTG+P P V WF + + + +D ++ I  ++ G H L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            +IT V  +D GV  C+A N  G ++ +  L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 65/220 (29%), Positives = 94/220 (42%), Gaps = 15/220 (6%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT--GSRVHTLNDFGFIALDIDYIY 3761
            +I V EG    F CRV   G P   + W  +GR      G RV         AL I    
Sbjct: 118  SIRVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAAR 175

Query: 3762 ARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPK 3821
             RD G Y  RA N  G+A+  A +   +  D    +  P   +   +  L+R R  +A +
Sbjct: 176  PRDGGTYEVRAENPLGAASAAAALVVDS--DAADTASRPGTSTAALLAHLQRRR--EAMR 231

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
             E   ++PP   T  ++ TV E +  R  C V    +PK    W ++G+L+  G R+   
Sbjct: 232  AEGAPASPPS--TGTRTCTVTEGKHARLSCYVTG--EPKPETVWKKDGQLVTEGRRHVVY 287

Query: 3882 YDM--GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             D    FV L IL+    D G Y C A N  G+ ++   +
Sbjct: 288  EDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 57/200 (28%), Positives = 88/200 (44%), Gaps = 14/200 (7%)

Query: 4428 ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAEN 4487
            A+F+++  G P P + W+++  P+  S   ++        L I  V  EDS  +AA   N
Sbjct: 5278 AKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISN 5337

Query: 4488 RGGTAKCSANLVV------EEKRRQG-RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
              G A  SA L+V      EEK        +VPP          V  G  +    KV G 
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR 5397

Query: 4541 KPIDVYWLKNGKK-----VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
                V+WL+   +     + PD     +      ++L++L+   Q  G Y C+A N+AG+
Sbjct: 5398 PVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457

Query: 4595 ARCDAECVVS-LPATKDKPK 4613
            A C A   VS LP  +++ K
Sbjct: 5458 ALCSASLHVSGLPKVEEQEK 5477



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 79/288 (27%), Positives = 115/288 (39%), Gaps = 19/288 (6%)

Query: 1835 DVEVA-VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL--QSGH 1891
            D E A   QAP F+ +     ++ EG  A + CR+   P P   V W  +G+ L    G 
Sbjct: 100  DAEAACAEQAPHFLLRPTS-IRVREGSEATFRCRVGGSPRP--AVSWSKDGRRLGEPDGP 156

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
            R R       +AL I      D G Y  +A N LG A ++  L V S  +        S 
Sbjct: 157  RVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTST 216

Query: 1952 LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
               + +L+   R + A++ +      P  G   +   VTEG    L   +T   +P    
Sbjct: 217  AALLAHLQ---RRREAMRAEGAPASPPSTGT--RTCTVTEGKHARLSCYVT--GEPKPET 269

Query: 2012 EWYCNGRPVQQGHRFKTTYDFGY-VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             W  +G+ V +G R     D      L IL+    D G Y C A+N VG+  T SSV V 
Sbjct: 270  VWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ--TYSSVLVV 327

Query: 2071 AKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSL 2118
             +         ++RL+ ++  EK       E  QP     +    T L
Sbjct: 328  VREPA---VPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRL 372



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 32/108 (29%), Positives = 60/108 (55%), Gaps = 1/108 (0%)

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
            P    +P P    ++A P  +  L+++ V +G  + F C + G+P+P+V+W+K  KL++ 
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEE 5168

Query: 4666 SKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
              ++ ++      + L I+   P D G Y+C+A NS G  +  A+L+V
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 7/239 (2%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SL 2833
            VF++ L N   ++G  + F+C V  +  P   + WF + K L     Y    D      L
Sbjct: 5127 VFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             IT     D G+Y C A NS G ++T   LR       Y         +   + +    +
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
            R  +G   +  + + P+   ++    + Q+  G  L  + Q++ K  P  ++ W+ +G+ 
Sbjct: 5245 REQEGTESTTDEGQLPQ---VVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFKDGQP 5300

Query: 2954 LEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
            L   +  ++T      TL+++ V   DSG Y     N  G A++S+ +     D   E+
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEK 5359



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 95/421 (22%), Positives = 163/421 (38%), Gaps = 45/421 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +F KK++P  V E      EVE    P P ++W R    +    + +IH    +  L+
Sbjct: 1987 PVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  V   D   F     +     K  A L VE ++ +   G+   +     Q       Q
Sbjct: 2046 LHNVGFADRGFFGCETPDD----KTQAKLTVEMRQVRLVRGL--QAVEAREQGTATMEVQ 2099

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
            L   D        +D  W ++G + Q      +      +TL +    P+DSG     A 
Sbjct: 2100 LSHAD--------VDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAE 2151

Query: 4590 NSAGEARCDA-ECVVSLP------ATKDKPKPQTKAANAPPEI-IEPLKDKI-VAEGQAI 4640
                 AR    E  VS         T +K K   +   + P + +  LKD + +  G+ +
Sbjct: 2152 GVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTM 2211

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD------EYTLRISEAFPEDEGDYK 4694
              + +   + L   +    D+ +          +A        YTL       ED G+ +
Sbjct: 2212 AIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQ 2271

Query: 4695 CVAYNSAGRVTVAAK-LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
             VA N+  R  +  K L VT          + PLRD +  E      + Q+ S+    ++
Sbjct: 2272 FVAENAESRAQLRVKELPVT---------LVRPLRDKIAMEKHRGVLECQV-SRASAQVR 2321

Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            W +    +   P ++++ +G    L+I + + ED  T+TC     AG V+TSA+  V+ +
Sbjct: 2322 WFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTC----DAGDVKTSAQFFVEEQ 2377

Query: 4814 T 4814
            +
Sbjct: 2378 S 2378



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 84/370 (22%), Positives = 146/370 (39%), Gaps = 47/370 (12%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W + +  ++    + +    T+  L I  + V D+  ++ V     G  + SA L V 
Sbjct: 3831 VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVR 3886

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
              +         P F    Q++    G    L  +++      V W K G ++Q + R +
Sbjct: 3887 APQ---------PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKGGLQLQANGRRE 3936

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
               +  T  L++ +   +D+G+Y C   + A  A        +L  T            A
Sbjct: 3937 PRLQGCTAELVLQDLQREDTGEYTCTCGSQATSA--------TLTVTA-----------A 3977

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   +  L+ + V EG      C++  +   +V+W KG   + P   +QM +      L 
Sbjct: 3978 PVRFLRELQHQEVDEGGTAHLCCEL-SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELL 4036

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            +     ED GDY C      G     A L V  P         T L+ +    G  A+  
Sbjct: 4037 VRGVEQEDAGDYTC----DTGHTQSMASLSVRVPRPKFK----TRLQSLEQETGDIARLC 4088

Query: 4742 TQIT-SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             Q++ ++    +QWL+EG  +   P ++M  +G    LLI     +DTG + C      G
Sbjct: 4089 CQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC----VTG 4144

Query: 4801 QVETSAKLVV 4810
              +T+A L V
Sbjct: 4145 GQKTAASLRV 4154



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 99/448 (22%), Positives = 173/448 (38%), Gaps = 45/448 (10%)

Query: 4349 DPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPS 4408
            DP+  TV GK V  + + Q  ++      + R+   ++  E+    +         V+  
Sbjct: 2766 DPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVR-E 2824

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P    K ++   V   E      E      P + W ++   I+ S  + +    T ++L
Sbjct: 2825 RPAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAML 2883

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +IR   ++D+  +    E     +K +A+L VEEK            FT    N+ V   
Sbjct: 2884 VIRGASLKDAGEYTCEVE----ASKSTASLHVEEKAN---------CFTEELTNLQVEEK 2930

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                   K T      V W K   +++   +++  +E  T  L I      DS  Y C  
Sbjct: 2931 GTAVFTCK-TEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTC-- 2987

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
                G+A+  A+ +V           Q +  +    IIE L+D  V EG +  F C+I  
Sbjct: 2988 --DIGQAQSRAQLLV-----------QGRRVH----IIEDLEDVDVQEGSSATFRCRISP 3030

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                 V W+     +  ++  ++      Y  L + +   +D G      Y  AG    +
Sbjct: 3031 ANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG----TIYFEAGDQRAS 3086

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            A L+VT+     +      L D  + EG+      + TS     + W ++G  +  +   
Sbjct: 3087 AALRVTEKPSVFS----RELTDATITEGEDLTLVCE-TSTCDIPVCWTKDGKTLRGSARC 3141

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            Q+ HEG+ A LLI     +D+G + C A
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEA 3169



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 81/369 (21%), Positives = 144/369 (39%), Gaps = 49/369 (13%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W++ +  +++     +     +  L IR +  ED+  +  +     G  + SA L V 
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVR 3710

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
                      +P  F    +N   T G    L  +++   P++  W K  + ++   R+ 
Sbjct: 3711 A---------MPSKFIEGLRNEEATEGDTATLWCELSKAAPVE--WRKGHETLRDGDRHS 3759

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            + ++     L I      D+G+Y CV     G+ R  A   V                  
Sbjct: 3760 LRQDGSRCELQIRGLAVVDAGEYSCVC----GQERTSATLTVRA---------------L 3800

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   IE +K++   EG      C++  K  P V+W KG + ++    + + +      L+
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQ 3858

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I      D G+Y CV     G+   +A L V  P          PL+ +   EG  A  +
Sbjct: 3859 IHGLSVADTGEYSCV----CGQERTSATLTVRAPQPVFR----EPLQSLQAEEGSTATLQ 3910

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             ++ S+   T+ W + G  +      +   +G  A L++ +   EDTG +TC      G 
Sbjct: 3911 CEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC----TCGS 3965

Query: 4802 VETSAKLVV 4810
              TSA L V
Sbjct: 3966 QATSATLTV 3974



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 47/198 (23%), Positives = 82/198 (41%), Gaps = 9/198 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + + R ++  +      ++  +D DV EG    F CR++   Y  V WF++   +  +  
Sbjct: 2991 QAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANEL 3050

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
            ++I     G H L +  + L DSG +      ++G+      L V EK  V    F    
Sbjct: 3051 NEIDAQPGGYHVLTLRQLALKDSGTIYF----EAGDQRASAALRVTEKPSV----FSREL 3102

Query: 498  STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            +   + EGE + L         P + W KDG  +  +   ++  +G  + L I  A   D
Sbjct: 3103 TDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQD 3161

Query: 558  AAWYQCTAQNVAGSTATR 575
            +  Y+C A     S+  R
Sbjct: 3162 SGRYKCEAGGACSSSIVR 3179



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 117/538 (21%), Positives = 213/538 (39%), Gaps = 53/538 (9%)

Query: 4280 KLQELENEQVIKESRLRESTHQYAIP-GDKVTSNTVAKSMAQ-RYEDNLDQTEEVTEQRV 4337
            +LQ    E V+++ + RE T +Y    G + TS T+  + A  R+   L Q +EV E   
Sbjct: 3938 RLQGCTAELVLQDLQ-REDTGEYTCTCGSQATSATLTVTAAPVRFLREL-QHQEVDEGGT 3995

Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQ 4397
                 +  R     E      ++    + Q  ++    + + R +   +  +        
Sbjct: 3996 AHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHT 4055

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEF-DGEPLPLIKWYRENFPIKNSPD 4456
            + +    V+  +P  F  ++Q       + AR   +  D E   +++W +E   +   P 
Sbjct: 4056 QSMASLSVRVPRPK-FKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPK 4114

Query: 4457 FQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
            +++ +      L+I Q+  +D+  +A V     G  K +A+L V E       G+V    
Sbjct: 4115 YEMRSQGATRELLIHQLEAKDTGEYACVT----GGQKTAASLRVTEPEVTIVRGLV---- 4166

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLILE 4575
                 +  VT+ + V    +V+      V W   G  +Q +   ++   DG  +TL +  
Sbjct: 4167 -----DAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKG 4221

Query: 4576 AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA 4635
              P+D+G       N A  A    +  V  P                  I+EPL+D  ++
Sbjct: 4222 VTPEDAGTVSFHLGNHASSA----QLTVRAPEVT---------------ILEPLQDVQLS 4262

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            EGQ   F C++        +W  G   ++ ++   +  T ++ TL +         D   
Sbjct: 4263 EGQDASFQCRLSRASGQEARWALGGVPLQANEMNDI--TVEQGTLHLLTLHKVTLEDAGT 4320

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            V+++  G  +  A+LKVT    A N   +  L ++   EG  A F+ Q++        WL
Sbjct: 4321 VSFH-VGTCSSEAQLKVT----AKN-TVVRGLENVEALEGGEALFECQLSQPEVAAHTWL 4374

Query: 4756 REGALI--PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +   +   E  +      G   +LL+ N   +D    +CR T  AG + TSA L V+
Sbjct: 4375 LDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQD----SCRVTFLAGDMVTSAFLTVR 4428



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 103/439 (23%), Positives = 178/439 (40%), Gaps = 54/439 (12%)

Query: 2043 YAEDTGTYMCKATNAVGEA--VTTSSVKVDAKSGLYLDT-LDEQRLKKIQELEKYERPKP 2099
            Y ED   ++C    A+ EA    T   ++ A  G+ ++  L EQ  ++++     E P P
Sbjct: 5051 YREDEH-FICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPAP 5109

Query: 2100 IEEEQP-------GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
            +   +P          PVFLT L + E +++G    F+C V     P  ++ WF +G+ +
Sbjct: 5110 VVPPEPLPSLLTSDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLL 5166

Query: 2153 RAGHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
                 Y    D  G   L I      D G Y C A N +G +     L+V    +   DT
Sbjct: 5167 EEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV-DLTSTDYDT 5225

Query: 2212 QHPNGLEKIRQLEAQGHSTRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQV 2266
               +  E      AQG+ +  E E  + +      P+ V ELR        + A F+ +V
Sbjct: 5226 A-ADATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV 5284

Query: 2267 EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHC 2326
            +    P  R+ ++ +G+ L ++A   +T      +L+I     ED+G+Y+    NA+G  
Sbjct: 5285 KGYPAP--RLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342

Query: 2327 TSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNID 2386
             S+  + V              G ++  E  +++  ++   P  + R  P          
Sbjct: 5343 YSSARLLV-------------RGPDEPEEKPASDVHEQLVPPRMLERFTP---------K 5380

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK------LIEDSSRITKTHDFGYVSMTISH 2440
             +++G +  F  ++   G P   V W R E       +  D+   T        S+ +  
Sbjct: 5381 KVKKGSSITFSVKV--EGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLD 5438

Query: 2441 VRDEDEGVYMCRASNLLGE 2459
            V  + +G Y C ASN  G+
Sbjct: 5439 VGRQHQGTYTCIASNAAGQ 5457



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 86/408 (21%), Positives = 164/408 (40%), Gaps = 42/408 (10%)

Query: 4390 IEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449
            IE   + + R   G +  +KPP    +    R+  HE+A+   E   +    + W ++  
Sbjct: 689  IESSIRMEVRAAPG-LTANKPPAAAAREVLARL--HEEAQLLAELSDQAAA-VTWLKDGR 744

Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
             +   P +++   + + +L++R V  +D+ ++  V+  RGG  + +  L V     QG  
Sbjct: 745  TLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVS--RGG--RIAYQLSV-----QGLA 795

Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT- 4568
              +     +    V+  +G   + + + T    + V+W K+G ++       + E+ GT 
Sbjct: 796  RFLHKD--MAGSCVDAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTR 852

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            + L+      QD G Y C      GE   D    VS P          K   A  ++   
Sbjct: 853  HRLVAATVTRQDEGTYSC----RVGEDSVDFRLRVSEP----------KVVFAKEQLA-- 896

Query: 4629 LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
             + K+ AE G +   SC+ V +    V WYK  K +  S    M  T     L + +A  
Sbjct: 897  -RRKLQAEAGASATLSCE-VAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQ 954

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
             D G+Y C     AG   ++  L V +P        +    ++    G  A    ++ ++
Sbjct: 955  ADAGEYSC----EAGGQRLSFHLDVKEPKVVFAKDQVAH-SEVQAEAGASATLSCEV-AQ 1008

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
             +  + W ++G  +  +    +  +G    L++    + D G ++C A
Sbjct: 1009 AQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 115/497 (23%), Positives = 193/497 (38%), Gaps = 63/497 (12%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+++   C +  +  P   + W  + K +    +Y    + +   L I     +D+G YT
Sbjct: 2841 GEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897

Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTE 2907
            C+   SK +A    SL      N + +         L+  E+       K   P+   T 
Sbjct: 2898 CEVEASKSTA----SLHVEEKANCFTEEL-----TNLQVEEKGTAVFTCKTEHPAATVT- 2947

Query: 2908 YPKPEWIIPIAAEHQ-LVEGQVLHLEGQVEPKNDPDLKI----EWYFNGKVLEQGSRFKL 2962
            + K    +  + +HQ   EG  L L      K D D       +     ++L QG R  +
Sbjct: 2948 WRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHI 3007

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA---FTSSTVYCTSKDNLIERTQHPKGT 3019
              D     L+ VDV E  S  + C+      E    F   T    ++ N I+    P G 
Sbjct: 3008 IED-----LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDA--QPGGY 3060

Query: 3020 EGLEKIQ-NLEDS--LRKEPGQQPDDDTGRPPEFTTVF-KDIVD--ISEGQIAHYEASLI 3073
              L   Q  L+DS  +  E G Q      R  E  +VF +++ D  I+EG+    + +L+
Sbjct: 3061 HVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE----DLTLV 3116

Query: 3074 -PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
              T    + + W  +GKT+  S R +  +      L I G    DSG Y C A      +
Sbjct: 3117 CETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSS 3176

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
             + V    V        RF   ++++E L +G +A   C +  V  P   ++W +    +
Sbjct: 3177 IVRVHARPV--------RFQEALKDLEVL-EGGAATLRCVLSSVAAP---VKWCYGNNVL 3224

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESL 3252
            R   +     +   + L +   +  DSG Y C     +G+  T AT+         + +L
Sbjct: 3225 RPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLT--------VTAL 3272

Query: 3253 QPDSLAKIRELESLQGA 3269
                + K+R  E+ +GA
Sbjct: 3273 PAQFIGKLRNKEATEGA 3289



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 91/367 (24%), Positives = 140/367 (38%), Gaps = 27/367 (7%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR-ITSIFNFGYV 828
            P F+  LQ+  E+Q+G    F+  +T    P   V W+KDG+ +      + +    G  
Sbjct: 5126 PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXX 888
             L I  +   D G Y   A N +G + + A +RV   ST   D                 
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTST---DYDTAADATESSSYFSAQ 5239

Query: 889  XXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKD 948
                           +  Q P+    ++D         A F+ +++  G    R+ W KD
Sbjct: 5240 GYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFKD 5297

Query: 949  GRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
            G+P+ AS+ I          L I SVT  D+G Y     NA+G A +SA L +V   D  
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL-LVRGPD-- 5354

Query: 1009 AESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVE 1068
             E +     +  + L       + T ++VK      F   ++G        + H+  R E
Sbjct: 5355 -EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR----PVPTVHW-LREE 5408

Query: 1069 PQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQ 1128
             +      V W   G          +      V LD+     +  G YT +A NAAG+A 
Sbjct: 5409 AERG----VLWI--GPDTPGYTVASSAQQHSLVLLDVG---RQHQGTYTCIASNAAGQAL 5459

Query: 1129 LSASMTV 1135
             SAS+ V
Sbjct: 5460 CSASLHV 5466



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 78/337 (23%), Positives = 123/337 (36%), Gaps = 56/337 (16%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+   +P+   +  G DA    Q+ GNP P+V+W K+ Q +    +  +    +   L +
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
            +    DSG Y   A N  G    +  L V++  E+   +Q   ++              
Sbjct: 70  LDLALGDSGQYVCRARNAIGEAFAAVGLQVDA--EAACAEQAPHFL-------------- 113

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE- 444
               L P  ++V       EG    F CRV G P P V+W  + R++ +    ++ V E 
Sbjct: 114 ----LRPTSIRV------REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 445 ---------------SGNHALMITNVTLSDSGVVTCVARNKSGETA-------------F 476
                           G + +   N   + S     V  + + +TA              
Sbjct: 164 GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHL 223

Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536
           Q R   +  E   A        T  V EG+   L+    G P P   W+KDG  +     
Sbjct: 224 QRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR 283

Query: 537 LRIHTDGGAS-TLDIPRAKASDAAWYQCTAQNVAGST 572
             ++ D   +  L I   K SD   Y CTA N+ G T
Sbjct: 284 HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 68/236 (28%), Positives = 104/236 (44%), Gaps = 18/236 (7%)

Query: 1041 QKPRFLGPLKGTN-KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN--RIQTYHD 1097
            Q P FL  L+ T+ ++ EG  A F  RV         V W  +G+++   +  R++    
Sbjct: 108  QAPHFL--LRPTSIRVREGSEATFRCRVGGSP--RPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
                AL I + R  D G Y V A N  G A  +A++ V++ ++   S           H+
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHL 223

Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
            +  +  E M + E    S P      +    V+EGK+  L C +   G+P     W  +G
Sbjct: 224  QRRR--EAM-RAEGAPASPP---STGTRTCTVTEGKHARLSCYVT--GEPKPETVWKKDG 275

Query: 1218 RSVTVGSRFKTYYDF--GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            + VT G R   Y D    FV L I+    +D G YT  A N +G  ++S +V V E
Sbjct: 276  QLVTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 38/130 (29%), Positives = 68/130 (52%), Gaps = 6/130 (4%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V   PRF+ ++   +   EG+ A + C IE  P P +R  WY +G +L +G++++T 
Sbjct: 6101 KILVQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTL 6157

Query: 1897 ND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH-ESALE 1953
            ++   G   L I     ED G Y C+ +N LG A +S  L +QS     ++  H E  + 
Sbjct: 6158 SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVA 6217

Query: 1954 KIQYLEDDSR 1963
             ++  E +++
Sbjct: 6218 AVEVTEQETK 6227



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 17/241 (7%)

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGASTL 548
            AP F+       V++G PV  +    G P P + W KDG  +  +    I+ D  G   L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXX 608
             I     +D   Y+C A+N  G ++T+A L                              
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDT---------AADATESSSY 5235

Query: 609  XXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKI-HFETRIEPVGDPT 667
                 YL   E+        E       PQ +  L+ +    G ++  F+ +++  G P 
Sbjct: 5236 FSAQGYLSSREQEGTESTTDEGQL----PQVVEELRDLQVAPGTRLAKFQLKVK--GYPA 5289

Query: 668  MKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLH 727
             ++ W K+GQ + AS+      +    +L+++S+  +DSG+Y     +A G A + A L 
Sbjct: 5290 PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLL 5349

Query: 728  V 728
            V
Sbjct: 5350 V 5350



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 90/382 (23%), Positives = 154/382 (40%), Gaps = 32/382 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL-KVEWFKNGQPVTIGHRFRPIHDF-GY 1501
            P F+T  ++ E V +G  V F+C    VT   +  V WFK+G+ +     +    D  G 
Sbjct: 5126 PVFLTELQNQE-VQDGYPVSFDCV---VTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST-TDI---VRSTQNEAGLEQIQV 1557
              L I  ++  D G+Y C A N +G       L    T TD      +T++ +       
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 1558 LEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR-AHFERRLIPVSDATLKVEWYHN 1616
            L  R +       DE   Q P     L+++++  G R A F+ ++        ++ W+ +
Sbjct: 5242 LSSREQEGTESTTDE--GQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKD 5297

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY 1676
             +PL + +    T+      L+I+S   EDSG Y     NA+G A +S   +V       
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD--- 5354

Query: 1677 LESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
             E + + A     QL      +R + +      +  F++ ++   V        EA    
Sbjct: 5355 -EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---- 5409

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
                +  V W+    P          H     +L +  V  +  GTYTC A N  G+A+ 
Sbjct: 5410 ----ERGVLWIGPDTPGYTVASSAQQH-----SLVLLDVGRQHQGTYTCIASNAAGQALC 5460

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
            S++L V     ++ + + + AL
Sbjct: 5461 SASLHVSGLPKVEEQEKVKEAL 5482



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 90/366 (24%), Positives = 137/366 (37%), Gaps = 46/366 (12%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PRF+TRPK+   V  G+     C++  V +   +V W K+ QPV  G RFR         
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFR--------- 57

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
                  +A+D  +Y    ++L   D  S +  CR+   I  +     GL+          
Sbjct: 58   ------LAQDGDLYRLTILDLALGD--SGQYVCRARNAIGEAFA-AVGLQ---------- 98

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPL--K 1621
                D       QAP       ++ ++EG  A F  R+         V W  + + L   
Sbjct: 99   ---VDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRV--GGSPRPAVSWSKDGRRLGEP 153

Query: 1622 SGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQH 1681
             G R          AL I +  P D GTY  RA N LG A  +   +V S  +       
Sbjct: 154  DGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPG 213

Query: 1682 EGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPK 1741
                  L  L+     +R + + E    +P  T   +   V E + A     +   G+PK
Sbjct: 214  TSTAALLAHLQ----RRREAMRAEGAPASPPST-GTRTCTVTEGKHARLSCYV--TGEPK 266

Query: 1742 LRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
                W ++G  +    R     D      L + +    D G YTC A N +G+  +S  +
Sbjct: 267  PETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326

Query: 1801 FVQSKA 1806
             V+  A
Sbjct: 327  VVREPA 332



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 63/221 (28%), Positives = 88/221 (39%), Gaps = 13/221 (5%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KTGHRFRPAYEFD 1366
            QAP F     +I   EG+     CR+   G     V W  +G+ +    G R R     +
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426
              AL + +  P D G Y  +A N LG A  S A  ++   D    +  P G      L  
Sbjct: 166  ASALRIRAARPRDGGTYEVRAENPLGAA--SAAAALVVDSDAADTASRP-GTSTAALLAH 222

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
              R ++    + +    P   TR  +   V EG+H    C +    +   +  W K+GQ 
Sbjct: 223  LQRRREAMRAEGAPASPPSTGTRTCT---VTEGKHARLSCYV--TGEPKPETVWKKDGQL 277

Query: 1487 VTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            VT G R     D      L I+     D G+YTC A NLVG
Sbjct: 278  VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 89/404 (22%), Positives = 157/404 (38%), Gaps = 50/404 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            KP +F++++    + E E      E     +P+  W ++   ++ S   Q+     ++ L
Sbjct: 3094 KPSVFSRELTDATITEGEDLTLVCETSTCDIPVC-WTKDGKTLRGSARCQLSHEGHRAQL 3152

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +I    ++DS  +   A   GG   CS+++V    R        P  F    +++ V  G
Sbjct: 3153 LITGATLQDSGRYKCEA---GGA--CSSSIVRVHAR--------PVRFQEALKDLEVLEG 3199

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                L   V  +    V W      ++P  +  + +E     L++    PQDSG+Y C  
Sbjct: 3200 GAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC-- 3256

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
              S G+    A   V+                 P + I  L++K   EG      C++  
Sbjct: 3257 --SFGDQTTSATLTVTA---------------LPAQFIGKLRNKEATEGATATLRCEL-S 3298

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            K  P V+W KG + ++    + + +      L+I      D  +Y CV     G    +A
Sbjct: 3299 KAAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCV----CGEERTSA 3353

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L + +P  A  +  L     I   EG  A  + ++ SK  P ++W +    + +     
Sbjct: 3354 SLTI-RPMPAHFIGRLRHQESI---EGATATLRCEL-SKAAP-VEWRKGRESLRDGDRHS 3407

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +  +G    L I      D G ++C      G+  TSA L VK+
Sbjct: 3408 LRQDGAVCELQICGLAVADAGEYSC----VCGEERTSATLTVKA 3447



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 13/222 (5%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            +PP F +++  C     E  +      G P P+I WY++   ++  P    I        
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI+  +   DS  +   A +  G       ++V+          VPP F    +      
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----------VPPRFVNKVRASPFVE 6121

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLILEAYPQDSGKYE 4585
            G+  +    + G     + W K+G  +    + + L E   G   L+I  A  +D G YE
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            C  +N  G AR  AE  +  P  + + +   +   A  E+ E
Sbjct: 6182 CELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 6223



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 64/236 (27%), Positives = 102/236 (43%), Gaps = 12/236 (5%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTFFN 963
            S   P F T +++Q  +++G    F+  +   G     V W KDG+ +E     +     
Sbjct: 5122 SDAAPVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI---VTKKDIIAESQHPGGLEKI 1020
             G   L I +V   D G Y C A N++G ++T A L +    T  D  A++         
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238

Query: 1021 Q-YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEW 1079
            Q YL  +SR  + TE      Q P+ +  L+        + A F+ +V+        + W
Sbjct: 5239 QGYL--SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYP--APRLYW 5294

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            + +G+ +T++  I+         L+I SV  EDSG Y     NA G A  SA + V
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 62/213 (29%), Positives = 86/213 (40%), Gaps = 14/213 (6%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV--GSRFKTYYDFGFVALDIIHATSAD 1246
            V EG      CR+   G P   V W  +GR +    G R +        AL I  A   D
Sbjct: 121  VREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT 1306
             G Y VRA N LG+A  SA   ++  SD   DT +        LL    RR + +R +  
Sbjct: 179  GGTYEVRAENPLGAA--SAAAALVVDSD-AADTASRPGTSTAALLAHLQRRREAMRAEGA 235

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF- 1365
                P  S         EG +  L C +   G+      W  +G+ +  G R    YE  
Sbjct: 236  PASPP--STGTRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQLVTEGRR-HVVYEDA 290

Query: 1366 -DYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             +   L +L     D G+YTC A+N +G+  +S
Sbjct: 291  QENFVLKILFCKQSDRGLYTCTASNLVGQTYSS 323



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 101/447 (22%), Positives = 171/447 (38%), Gaps = 48/447 (10%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P F T   +  + +     F+C  +        V WF +GK L          D  G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V   D G+Y C A N  G ++   +L+V     +       +   + + S    +
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVD----LTSTDYDTAADATESSSYFSAQ 5239

Query: 3677 ETLHKREEITIED--EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
              L  RE+   E   ++   P+   E++D    P      F  +V+  G P  R+ WF +
Sbjct: 5240 GYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFKD 5297

Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            G+P    + +   +      L+I  +   D+G+Y    +N  G+A ++A++         
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL--------- 5348

Query: 3795 LESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVE 3854
                L +G       E E    SD    E +V  PP+ + +     V++   + F  +VE
Sbjct: 5349 ----LVRGPD-----EPEEKPASDV--HEQLV--PPRMLERFTPKKVKKGSSITFSVKVE 5395

Query: 3855 PKEDPKLRIEWYR----NGKLL--PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
             +  P   + W R     G L   P    Y         SL +L V  +  G Y C A N
Sbjct: 5396 GRPVP--TVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASN 5453

Query: 3909 DFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTED--DLYD 3966
              G+    A++    LP +  Q +V    K +   T ++ T +  +++   T    DL  
Sbjct: 5454 AAGQALCSASLHVSGLPKVEEQEKV----KEALISTFLQGTTQAISAQGLETASFADL-G 5508

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKF 3993
              +K+ P    +     SL E+ T +F
Sbjct: 5509 GQRKEEPLAAKEALGHLSLAEVGTEEF 5535



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 73/324 (22%), Positives = 126/324 (38%), Gaps = 29/324 (8%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P   + W+ +GK+LE+   + +  D  G   L +  V   D G+Y C A N  G + T +
Sbjct: 5153 PMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKA 5212

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD 3059
             +         +       +      Q    S R++ G +   D G+ P+     +D+  
Sbjct: 5213 ELRVDLTSTDYDTAADATESSSYFSAQGYLSS-REQEGTESTTDEGQLPQVVEELRDLQV 5271

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
                ++A ++  +   G  +  + WF +G+ + AS  IR      +  LEI+     DSG
Sbjct: 5272 APGTRLAKFQLKV--KGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSG 5329

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNI----------EGLKDGQSAH 3168
             Y+   +N  G A  S +L      +  +KP    H Q +          + +K G S  
Sbjct: 5330 QYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSIT 5389

Query: 3169 FECTV----VPV-----DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
            F   V    VP      ++ +  + W   G      T   +      V+LD+   + H  
Sbjct: 5390 FSVKVEGRPVPTVHWLREEAERGVLWI--GPDTPGYTVASSAQQHSLVLLDVG--RQH-Q 5444

Query: 3220 GEYVCRAYNKYGEDFTRATINCYG 3243
            G Y C A N  G+    A+++  G
Sbjct: 5445 GTYTCIASNAAGQALCSASLHVSG 5468



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 82/373 (21%), Positives = 150/373 (40%), Gaps = 54/373 (14%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W + +  +++   + +    TK  L IR + + D+  ++ V     G  + SA L V 
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVC----GQERTSAMLTVR 3622

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
                      +P  FT   +N   T G    L  +++   P++  W K  + ++   R+ 
Sbjct: 3623 A---------LPIKFTEGLRNEEATEGATAVLRCELSKMAPVE--WWKGHETLRDGDRHS 3671

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            + ++     L I     +D+G+Y C+     G+ R  A   V                  
Sbjct: 3672 LRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRA---------------M 3712

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P + IE L+++   EG      C++  K  P V+W KG + ++      + +      L+
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCEL-SKAAP-VEWRKGHETLRDGDRHSLRQDGSRCELQ 3770

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQ 4739
            I      D G+Y CV     G+   +A L V        LPA  +  +++    EG  A 
Sbjct: 3771 IRGLAVVDAGEYSCV----CGQERTSATLTVRA------LPARFIEDVKNQEAREGATAV 3820

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
             + ++ SK  P ++W +    +     + +  +G    L I      DTG ++C      
Sbjct: 3821 LQCEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC----VC 3874

Query: 4800 GQVETSAKLVVKS 4812
            GQ  TSA L V++
Sbjct: 3875 GQERTSATLTVRA 3887



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 6/133 (4%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD- 3883
            +V  PP+F+ ++++    E E  +F C +E    P++R  WY++G LL +G++++T+ + 
Sbjct: 6103 LVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 6160

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR-GMKRSE 3941
              G + L I     ED G Y C  VN  G     A +  +  P +  Q Q  R  +  + 
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS-PMLQAQEQCHREQLVAAV 6219

Query: 3942 ALTQMEATIKKYT 3954
             +T+ E  + K T
Sbjct: 6220 EVTEQETKVPKKT 6232



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 3/122 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
            PP+   K R S   EG DAQF   + G P P++ W+K+G  L   NK + ++        
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 6166

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP-TESYVQDQRSQYITDTQQRETEE 381
            L +R   K D G Y     N  G    S  L ++SP  ++  Q  R Q +   +  E E 
Sbjct: 6167 LVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQET 6226

Query: 382  RI 383
            ++
Sbjct: 6227 KV 6228



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 61/238 (25%), Positives = 105/238 (44%), Gaps = 15/238 (6%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GF 3477
            APVF   L N E +++G    F+  +T    P+  V W+ +GK L+    +    D  G 
Sbjct: 5125 APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPS--VRWFKDGKLLEEDDHYMINEDQQGG 5181

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIA 3536
              L I+   P D G Y C A N+ G + T A ++V      +  +      + T      
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-----LTSTDYDTAADATESSSYF 5236

Query: 3537 ALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSS-AHFECRLIPVNDSSMRVEW 3593
            + +GY  + +    E+  + G  P+      DL ++  +  A F+ ++      + R+ W
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYW 5294

Query: 3594 FHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            F +G+PL   + ++  +      LEI  V + D+G Y    +N  G A  S +L V+G
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 58/219 (26%), Positives = 95/219 (43%), Gaps = 16/219 (7%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            + V + P  FSR L ++ T E   V LEC L       + V W  +G  ++ G     A 
Sbjct: 2159 LVVTELPVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAA 2215

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK-DLILESQHPSGLEKIQ 1422
            +    +L +      D GVY C A     +A +S +++V  +   LI          +IQ
Sbjct: 2216 QGACRSLTIYRCEFADQGVYVCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQ 2271

Query: 1423 YLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK 1482
            ++ + +  +    + E     P  + RP   +  +E      EC+   V+ ++ +V WFK
Sbjct: 2272 FVAENAESRAQLRVKEL----PVTLVRPLRDKIAMEKHRGVLECQ---VSRASAQVRWFK 2324

Query: 1483 NGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
              Q +  G ++  + D  Y  L I D+ AED   YTC A
Sbjct: 2325 GSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 63/255 (24%), Positives = 108/255 (42%), Gaps = 28/255 (10%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            V WLK+G +++   R++   +  T+TL +  A   DS  Y C         R  AE    
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC---------RVGAE---- 1796

Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
                +D P    + A     ++EP+  ++   G  +  +C++       V W  G+  ++
Sbjct: 1797 ---GQDFPVQVEEVAAKFCRLLEPVCGEL---GGTVTLACEL-SPACAEVVWRCGNTQLR 1849

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
              K FQM       +L +     ED G+Y C + +       +A+L V+ P     +  +
Sbjct: 1850 VGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDD----HTSAQLTVSVPRV---VKFM 1902

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
            + L  +V  EG  A F+  + S     + W R+GAL+  +  F +   G +  L I +  
Sbjct: 1903 SGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLV 1961

Query: 4785 EEDTGTFTCRATTAA 4799
             ED G  T  A  A+
Sbjct: 1962 LEDAGQITVEAEGAS 1976



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 50/203 (24%), Positives = 86/203 (42%), Gaps = 12/203 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            E + V LE ++   + PN+ + W K+GV L  G  +         +L+I      D G+Y
Sbjct: 2179 EKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVY 2235

Query: 2716 TCKATNLLGEAVSTASIKIEDRHW-LLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXX 2774
             C A     +A S+AS+K++ R + L+   +  +    I  +                  
Sbjct: 2236 VCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVT 2291

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            + +  L + +  E      EC V  +   + ++ WF  ++ L  G +Y+   D  Y  L 
Sbjct: 2292 L-VRPLRDKIAMEKHRGVLECQVSRA---SAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347

Query: 2835 ITHTYEEDSGIYTCKATNSKGSA 2857
            I+  + ED   YTC A + K SA
Sbjct: 2348 ISDVHAEDEDTYTCDAGDVKTSA 2370



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 59/261 (22%), Positives = 108/261 (41%), Gaps = 29/261 (11%)

Query: 1700 HSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            H++   V+T+ PV F+ P++D+   E +    E  L     P + V WL++GV + A   
Sbjct: 2154 HTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKT 2210

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            +         +L +      D G Y C A +             QS AS++++ +  + +
Sbjct: 2211 MAIAAQGACRSLTIYRCEFADQGVYVCDAHD------------AQSSASVKVQGRTYTLI 2258

Query: 1819 QKIQQLEDSSRYQ-----RREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPD 1873
             +    ED+   Q          ++ V + P  + +        E      EC++     
Sbjct: 2259 YRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSR--- 2315

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             + +V W+   + LQ G +Y   +D  +  L I  V+ ED   YTC A    G   +S +
Sbjct: 2316 ASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQ 2371

Query: 1934 LNVQSKE-SIIRDSQHESALE 1953
              V+ +  +I+R  Q  + +E
Sbjct: 2372 FFVEEQSITIVRGLQDVTVME 2392



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 49/180 (27%), Positives = 78/180 (43%), Gaps = 15/180 (8%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            QD + TE     F C ++     EV W +N   + +D  H+I  ++   H L++ ++  +
Sbjct: 2565 QDAEATEEGWASFSCELSHED-EEVEWSLNGMPLYNDSFHEIS-HKGRRHTLVLKSIQRA 2622

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G+V    R  S + +   RL V  K  V    F++    L+  E   + L    V  P
Sbjct: 2623 DAGIV----RASSLKVSTSARLEVRVKPVV----FLKALDDLSAEERGTLALQCE-VSDP 2673

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               + W+KDGV + P+ +       G   L +      DA  Y C      GS  TRAR+
Sbjct: 2674 EAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARV 2729



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 60/234 (25%), Positives = 95/234 (40%), Gaps = 8/234 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIV 3340
            P F+T++Q+  ++ +G    F+   V    P   V WF +GK L     Y    D  G  
Sbjct: 5126 PVFLTELQN-QEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400
             L I      + G Y C+A N +G  STKA L+     +   D+             Q  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELR-VDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
              S   ++ T    ++G+ P     L +++       A F+ ++     P L   W+ +G
Sbjct: 5242 LSSR-EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRL--YWFKDG 5298

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            + L A +  R         LEI     EDSG+Y     N  G A ++A + V+G
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 65/284 (22%), Positives = 116/284 (40%), Gaps = 28/284 (9%)

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            ++ V   +G    L  +V   +  +V W K+GKK+    + ++     T  L++ EA   
Sbjct: 1541 SREVQAEAGTSATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQA 1599

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQ 4638
            D+G+Y C     AG+ R      V+ P          K   A  +   P   ++ AE G 
Sbjct: 1600 DAGEYSC----KAGDQRLSFHLHVAEP----------KVVFAKEQ---PAHREVQAEAGA 1642

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            +   SC+ V +    V WYK  K +  S   ++        L + +A   + G+Y C   
Sbjct: 1643 SATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSC--- 1698

Query: 4699 NSAGRVTVAAKLKVTQPD-QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
              AG   ++ +L+V + + Q    P       +VV E +       + +    T+ WL++
Sbjct: 1699 -EAGGQQLSFRLQVAELEPQISERPCRR--EPLVVKEHEDIILTATLATPSAATVTWLKD 1755

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
            G  I  +   +   +G+   L +      D+  ++CR   A GQ
Sbjct: 1756 GVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCR-VGAEGQ 1798



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 101/402 (25%), Positives = 157/402 (39%), Gaps = 48/402 (11%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLP-LIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            TK+++   V E E   FE     E       W      + +S  FQ      K IL++R+
Sbjct: 2739 TKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVRE 2798

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
                D+     V   RG T+K  A+L+V E+       I+ P   L  Q V       +R
Sbjct: 2799 AAPSDAG--EVVFSVRGLTSK--ASLIVRERP----AAIIKP---LEDQWVAPGEDVELR 2847

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
             +    GT    V+WLK+ K ++   +  ++ E GT  +L++             ++  A
Sbjct: 2848 CELSRAGTP---VHWLKDRKAIRKSQKYDVVCE-GTMAMLVIRG----------ASLKDA 2893

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
            GE  C+ E   S  +   + K     AN   E +  L+  +  +G A+ F+CK    P  
Sbjct: 2894 GEYTCEVEASKSTASLHVEEK-----ANCFTEELTNLQ--VEEKGTAV-FTCK-TEHPAA 2944

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            TV W KG   ++ S   Q S+      L IS     D   Y C      G+    A+L V
Sbjct: 2945 TVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLV 3000

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM-IH 4771
                Q   +  +  L D+ V EG  A F+ +I+      + W  +   +      ++   
Sbjct: 3001 ----QGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQ 3056

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             G   VL +     +D+GT        AG    SA L V  K
Sbjct: 3057 PGGYHVLTLRQLALKDSGTIYFE----AGDQRASAALRVTEK 3094



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 49/189 (25%), Positives = 77/189 (40%), Gaps = 14/189 (7%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS-HRIRTVYAFG 3104
            RPP+F    +++ D +       + +   TG    VI W+ +GK ++   H I      G
Sbjct: 6012 RPPDFE---EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG 6068

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +      DSG Y C A +  G      K+          PRF   ++      +G
Sbjct: 6069 SCALILDSLTGVDSGQYMCFAASAAGNCSTLGKI-----LVQVPPRFVNKVR-ASPFVEG 6122

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEY 3222
            + A F CT+     P  +I WY +G  +    + +T+S+   G +VL I      D G Y
Sbjct: 6123 EDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 6180

Query: 3223 VCRAYNKYG 3231
             C   N+ G
Sbjct: 6181 ECELVNRLG 6189



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 78/361 (21%), Positives = 140/361 (38%), Gaps = 38/361 (10%)

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
            +P   + WY++   + +S   ++        L+++QV   D+  ++  A    G  + S 
Sbjct: 1192 QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSF 1247

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             L + E +       V     L    V   +G    L  +V   +  +V W K+GKK+  
Sbjct: 1248 QLHITEPKA------VFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSS 1300

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
              + +I        L++ +A   D+G+Y C     AG  R      VS P          
Sbjct: 1301 SSKVRIEAAGCMRQLVVQQAGQADAGEYTC----EAGGQRLSFHLDVSEP---------- 1346

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIE-FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675
            KA  A  ++      K+ AE  AI   SC+ V +    V WYK  K +  S   +M    
Sbjct: 1347 KAVFAKEQLAHR---KVQAEAGAIATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRMEAVG 1402

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RDIVVYE 4734
                L + +A   D G+Y C     AG   ++  L V +P          P+ R++    
Sbjct: 1403 CTRRLVVQQACQADTGEYSC----EAGGQRLSFSLDVAEPKVV--FAKEQPVHREVQAQA 1456

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G       ++ ++ +  + W ++G  +  +   +M   G    L++    +   G ++C 
Sbjct: 1457 GASTTLSCEV-AQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCE 1515

Query: 4795 A 4795
            A
Sbjct: 1516 A 1516



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 76/357 (21%), Positives = 142/357 (39%), Gaps = 40/357 (11%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S   ++        L+++Q    D+  ++  A    G  + S +L V 
Sbjct: 1381 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVA 1436

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E +      +V        + V   +G    L  +V   +  +V W K+GKK+    + +
Sbjct: 1437 EPK------VVFAKEQPVHREVQAQAGASTTLSCEVAQAQT-EVMWYKDGKKLSFSSKVR 1489

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +     T  L++ +A    +G+Y C     AG  R      V+ P          KA  A
Sbjct: 1490 MEAVGCTRRLVVQQAGQAVAGEYSC----EAGSQRLSFHLHVAEP----------KAVFA 1535

Query: 4622 PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
              +   P   ++ AE G +   SC+ V +    V WYK  K +  S   +M        L
Sbjct: 1536 KEQ---PASREVQAEAGTSATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRL 1591

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ--ADNLPALTPLRDIVVYEGQPA 4738
             + EA   D G+Y C     AG   ++  L V +P    A   PA    R++    G  A
Sbjct: 1592 VVQEAGQADAGEYSC----KAGDQRLSFHLHVAEPKVVFAKEQPA---HREVQAEAGASA 1644

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
                ++ ++ +  + W ++G  +  +   ++   G    L++    + + G ++C A
Sbjct: 1645 TLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEA 1700



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 59/230 (25%), Positives = 95/230 (41%), Gaps = 8/230 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFV 2566
            P+F   L    E+ +G    ++  V     PS+R  W+ +G  L+    +    D  G  
Sbjct: 5126 PVFLTELQN-QEVQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAM-RPESWEQIQLKEAA 2625
             L I +VV  D G+Y C A N  G                 D A    ES      +   
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 2626 MNKVPEMFVDTGVQ-QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684
             ++  E    T  + Q P     L+   ++  G  +  + Q++ +  P  ++ WFK+G  
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDL-QVAPGTRL-AKFQLKVKGYPAPRLYWFKDGQP 5300

Query: 2685 LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            LT  A ++ T    L TL I S+  +DSG Y    +N +G A S+A + +
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 53/211 (25%), Positives = 88/211 (41%), Gaps = 10/211 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYV 4031
            P F+T++Q+Q  + +     F+C +   G P   V WF +GK L   + +    D  G  
Sbjct: 5126 PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE-- 4089
             +    V P D G Y C A N  G+  TKA ++        YD+       S     +  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-LTSTDYDTAADATESSSYFSAQGY 5241

Query: 4090 MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            + +  Q   E   +E +   P V   L D         A+F  +V G+P PR+ W  +G 
Sbjct: 5242 LSSREQEGTESTTDEGQL--PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQ 5299

Query: 4150 TIVNGSRYKLTYDGMYH-FDIPKTRQYDTGK 4179
             +   +  ++T   + H  +I    + D+G+
Sbjct: 5300 PLTASAHIRMTDKKILHTLEIISVTREDSGQ 5330



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+F           G +  L C++  VG+ T +V W  + +P+  G RFR A + D   
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
            L +L +   DSG Y C+A N +GEA  +  L+V A+     ++ H
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 64/252 (25%), Positives = 101/252 (40%), Gaps = 21/252 (8%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F+ PL ++    E E    E  L+    PN+ V W  +G  L+AG             L 
Sbjct: 2168 FSRPLQDVVTT-EKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGY 3541
            I      D G Y+C A+    +A ++AS+KVQG+   ++  ++     G I  +A  E  
Sbjct: 2224 IYRCEFADQGVYVCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVA--ENA 2277

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
                     E     P        D I  E      EC+   V+ +S +V WF   + L 
Sbjct: 2278 ESRAQLRVKEL----PVTLVRPLRDKIAMEKHRGVLECQ---VSRASAQVRWFKGSQELQ 2330

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ----VKGRQGIIL 3657
             G + + ++D  +  L I  V+  D   YTC A +    A    + Q    V+G Q + +
Sbjct: 2331 PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTV 2390

Query: 3658 EPQLPSHFKSGT 3669
                P+ F+  T
Sbjct: 2391 MEPAPAWFECET 2402



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 33/106 (31%), Positives = 57/106 (53%), Gaps = 3/106 (2%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            APRF+T+      +S G+ A   C+I   P P  +V W  + + + +G R+R + D    
Sbjct: 9    APRFLTRPKAFV-VSVGKDATLSCQIVGNPTP--QVSWEKDQQPVAAGARFRLAQDGDLY 65

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
             L IL +   DSG+Y C+A N +G+A +++ L V ++ +    + H
Sbjct: 66   RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 72/355 (20%), Positives = 139/355 (39%), Gaps = 36/355 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S    +     +  L+++Q    D+  ++   E RG       + + E
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC--EARGQRVSFRLH-ITE 1069

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
             K    +   V       A    + S ++ +  T+VT        W K+GKK+    +  
Sbjct: 1070 PKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVT--------WYKDGKKLSSSSKVG 1121

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +  +  T  L++ +A   D+G+Y C     AG  R      ++ P          K   A
Sbjct: 1122 MEVKGCTRRLVLPQAGKADAGEYSC----EAGGQRVSFHLHITEP----------KGVFA 1167

Query: 4622 PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
              + +    +++ AE G     SC+ V +P   V WYK  K +  S   +M        L
Sbjct: 1168 KEQSVH---NEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRL 1223

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             + +    D G+Y C     AG   V+ +L +T+P        L    ++    G  A  
Sbjct: 1224 VVQQVGKADAGEYSC----EAGGQRVSFQLHITEPKAVFAKEQLVH-NEVRTEAGASATL 1278

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
              ++ ++ +  + W ++G  +  +   ++   G    L++    + D G +TC A
Sbjct: 1279 SCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 143/711 (20%), Positives = 251/711 (35%), Gaps = 54/711 (7%)

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLT 4160
            E + A   P F+  P ++ V EG  A F CRV G P+P V W  +G  +   +G R ++ 
Sbjct: 102  EAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVE 161

Query: 4161 YDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR---GVLKNAPRP 4216
              G      I   R  D G  EV              L V     D     G    A   
Sbjct: 162  ELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLA 221

Query: 4217 WYDETTQYQRTE--TELEKTFEERQVLQRQGVIDHRPELKPKVIKEP--ETEWQQSVKRK 4272
                  +  R E       +   R     +G       L   V  EP  ET W++  +  
Sbjct: 222  HLQRRREAMRAEGAPASPPSTGTRTCTVTEG---KHARLSCYVTGEPKPETVWKKDGQLV 278

Query: 4273 KNEEYYNKLQELENEQVIKESRLRESTH-QYAIPGDKVTSNTVAKSMAQRYEDNLDQTEE 4331
                 +   ++ +   V+K    ++S    Y      +   T +  +    E  +   + 
Sbjct: 279  TEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKR 338

Query: 4332 VTEQRVQKK--VTQKPRIPDPS-ESTVHGKEVHV-AKQKQTQKEVVGDKEITRKITSTET 4387
            + +  V++K   T    +P PS E+    +E  + A  K   +E   ++ +T +  S + 
Sbjct: 339  LQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADD 398

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
              + +  +T E          +  +  K  +   V   + A F VE    P+  + W R 
Sbjct: 399  DAV-YICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVEL-AVPVGPVHWLRN 456

Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
               +       I    T+  L I Q  +ED    A +A    G  + S    V   R+  
Sbjct: 457  QEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMA----GDCQTSTQFCVSAPRKP- 511

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP--IDVYWLKNGK-KVQPDIRNKILE 4564
               + PP   +      + S  ++       G +P  ID Y ++  K      IR    E
Sbjct: 512  --PLQPPVDPVV--KARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAE 567

Query: 4565 EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD-KPKPQTKAANAPP 4623
               T  L + +   + + ++   A+NS G++       +  P T    PK   +      
Sbjct: 568  WVATPELTVADVAEEGNFQFRVSALNSFGQSP-----YLEFPGTVHLAPKLAVRT----- 617

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
                PLK     EG  + FS  +        +W+   + +K S  +++      +TL I 
Sbjct: 618  ----PLKAVQAVEGGEVTFSVDLT--VASAGEWFLDGQALKASSVYEIHCDRTRHTLTIR 671

Query: 4684 EAFPEDEG-DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
            E      G   K VA      + +  +     P    N P     R+++    + AQ   
Sbjct: 672  EVPASLHGAQLKFVANGIESSIRMEVR---AAPGLTANKPPAAAAREVLARLHEEAQLLA 728

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +++ +    + WL++G  +   P +++       VLL+ +   +D G + C
Sbjct: 729  ELSDQ-AAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 69/275 (25%), Positives = 110/275 (40%), Gaps = 25/275 (9%)

Query: 1974 VVEKP-QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P  F +P+++   TE   V LE  L+    P + V W  +G  ++ G         
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQG 2217

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG--LYLDTLDEQRLKKIQE 2090
               +L I      D G Y+C A +A   A    SVKV  ++   +Y   L E    +IQ 
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDAQSSA----SVKVQGRTYTLIYRRVLAEDA-GEIQF 2272

Query: 2091 LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQ 2150
            +   E  +   + +  + PV L      +   E  R   EC+V   +     + WF   Q
Sbjct: 2273 VA--ENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRAS---AQVRWFKGSQ 2327

Query: 2151 KIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILD 2210
            +++ G +Y    D  Y  L I   +AED  TY C A +     V T        ++I + 
Sbjct: 2328 ELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD-----VKTSAQFFVEEQSITI- 2381

Query: 2211 TQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV 2245
                 GL+ +  +E        E   P + PP+++
Sbjct: 2382 ---VRGLQDVTVMEPAPAWFECETSIPSVRPPKWL 2413



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 5/115 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            VQ  P F   +++    VEG+       +E    P  +I W+K+G  LTTG + ++  + 
Sbjct: 6104 VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEP 6160

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
              GL+ L I +   +D G+Y C+  N LG A ++A ++I+       E  H + L
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL 6215



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 4/128 (3%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
            ++P  S  P+F+T+ K+  V   +     C++     P+  + W ++ + + +G R+R  
Sbjct: 2    DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQ--VSWEKDQQPVAAGARFRLA 59

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSE 3941
             D     L IL +   DSG+Y+CRA N  GE F  A +  +   +     Q P  + R  
Sbjct: 60   QDGDLYRLTILDLALGDSGQYVCRARNAIGEAF--AAVGLQVDAEAACAEQAPHFLLRPT 117

Query: 3942 ALTQMEAT 3949
            ++   E +
Sbjct: 118  SIRVREGS 125



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 91/404 (22%), Positives = 155/404 (38%), Gaps = 48/404 (11%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFV 3207
            P F T +QN E ++DG    F+C V     P   + W+ +G+ +          D  G  
Sbjct: 5126 PVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQ 3267
             L I      D G Y C A N  G   T+A +       V L S   D+ A   E  S  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELR------VDLTSTDYDTAADATESSSYF 5236

Query: 3268 GAQQQTPS---------TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEW 3318
             AQ    S         T   + P+ + +++D+      + A F+ ++     P  ++ W
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYW 5294

Query: 3319 FYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            F +G+ L      R      +  L+I+    E+SG+Y    +N +G   + A L      
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL------ 5348

Query: 3379 NLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENA 3438
             L+     P          Q +   M+ R  T  + +KG +  F+V +      R     
Sbjct: 5349 -LVRGPDEPEEKPASDVHEQLVPPRMLER-FTPKKVKKGSSITFSVKVEG----RPVPTV 5402

Query: 3439 HFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAY 3498
            H+   L    +  +     W G      +   +      V+L++     +  G Y C A 
Sbjct: 5403 HW---LREEAERGV----LWIGPDTPGYTVASSAQQHSLVLLDVG---RQHQGTYTCIAS 5452

Query: 3499 NNYGEAVTTASMKVQG-----KRNIILESQLPKGMEGTIDKIAA 3537
            N  G+A+ +AS+ V G     ++  + E+ +   ++GT   I+A
Sbjct: 5453 NAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISA 5496



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 10/146 (6%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FGF 1234
            P FV  +   P V EG++    C +E  G P  ++ W+ +G  +T G++F+T  +   G 
Sbjct: 6108 PRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQLLED 1293
            + L I  A+  D G Y    VN LGSA  SA +R+             EQ +  +++ E 
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQ 6224

Query: 1294 ---AARRTKQVREDI-TVMQAPQFSR 1315
                 ++T  + E I TV+++P+  R
Sbjct: 6225 ETKVPKKTVIIEETITTVVKSPRGQR 6250



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 51/241 (21%), Positives = 103/241 (42%), Gaps = 24/241 (9%)

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            R  NTQ      + ++AE P   +   G  A ++           +Y+ +++   T  ++
Sbjct: 1842 RCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDA----------GEYVCESRDDHTSAQL 1891

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
             +S   +  +F+         EG    F C V+      V WF +   ++   + K  ++
Sbjct: 1892 TVSVPRVV-KFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQP--SEKFAIS 1947

Query: 444  ESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +SG +H+L I+++ L D+G +T  A   S   A + R   +  ++ + P+ VE  S++ +
Sbjct: 1948 QSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTL 2007

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             E E        +  P P + W ++   + P   + IH +G    L +     +D  ++ 
Sbjct: 2008 -EVE--------LTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFG 2058

Query: 563  C 563
            C
Sbjct: 2059 C 2059



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 36/138 (26%), Positives = 65/138 (47%), Gaps = 6/138 (4%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD- 1498
            V + PRFV + ++    +EG+   F C +E      ++  W+K+G  +T G++F+ + + 
Sbjct: 6104 VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 6160

Query: 1499 -FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLEQIQ 1556
              G + L I     ED G+Y C  VN +G+   S  L  +S           E  +  ++
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVE 6220

Query: 1557 VLEDRSKYHRTDMVDEVT 1574
            V E  +K  +  ++ E T
Sbjct: 6221 VTEQETKVPKKTVIIEET 6238



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 69/302 (22%), Positives = 120/302 (39%), Gaps = 39/302 (12%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT- 4570
            +P  FT   +N     G    L  +++   P++  W K  + ++   R  IL ++GT   
Sbjct: 3448 LPAKFTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCE 3504

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L I      D+G+Y CV     G+ R  A   +                  P   IE +K
Sbjct: 3505 LQICGLAMADAGEYLCVC----GQERTSATLTIRA---------------LPARFIEDVK 3545

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
            ++   EG      C++       V+W KG + ++    + + +   +  L+I      D 
Sbjct: 3546 NQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADT 3603

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G+Y CV     G+   +A L V    +A  +     LR+    EG  A  + ++ SK+ P
Sbjct: 3604 GEYSCV----CGQERTSAMLTV----RALPIKFTEGLRNEEATEGATAVLRCEL-SKMAP 3654

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             ++W +    + +     +  +G    L I     ED G + C      G+  TSA L V
Sbjct: 3655 -VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLC----MCGKERTSAMLTV 3709

Query: 4811 KS 4812
            ++
Sbjct: 3710 RA 3711



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 27/70 (38%), Positives = 40/70 (57%)

Query: 2004 VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            V +PT +V W  + +PV  G RF+   D     L IL     D+G Y+C+A NA+GEA  
Sbjct: 34   VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFA 93

Query: 2064 TSSVKVDAKS 2073
               ++VDA++
Sbjct: 94   AVGLQVDAEA 103



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 40/141 (28%), Positives = 67/141 (47%), Gaps = 6/141 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V   P+F   +     VEG +    C ++  G    ++ W+ +G  + TG++F+   E
Sbjct: 6102 ILVQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 1365 --FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL-EKI 1421
                 + L + +   ED G+Y C+  N+LG A  S  LR+ +      E  H   L   +
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAV 6219

Query: 1422 QYLE-DTSRYKKTDIIDESVT 1441
            +  E +T   KKT II+E++T
Sbjct: 6220 EVTEQETKVPKKTVIIEETIT 6240



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 4/78 (5%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEY 144
           G +A    ++ GNPTP VSW + + P+    ++ +    Q GD+  L I  +  GD G+Y
Sbjct: 24  GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA---QDGDLYRLTILDLALGDSGQY 80

Query: 145 TCTARNQYGEAICSVYIQ 162
            C ARN  GEA  +V +Q
Sbjct: 81  VCRARNAIGEAFAAVGLQ 98



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 40/164 (24%), Positives = 66/164 (40%), Gaps = 7/164 (4%)

Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           D   G   +F+C  T   +  V W+ +  ++       +  +    H L+   VT  D G
Sbjct: 808 DAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEG 866

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
             +C    + GE +   RL V E + V A + + R   L    G    L+       T  
Sbjct: 867 TYSC----RVGEDSVDFRLRVSEPKVVFAKEQLAR-RKLQAEAGASATLSCEVAQAQT-E 920

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           +TW KDG  +  + ++ +   G    L + +A  +DA  Y C A
Sbjct: 921 VTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 79/378 (20%), Positives = 148/378 (39%), Gaps = 33/378 (8%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GL 2699
            AP+F T L++ + + +G  V  +  V  +  P+++  WFK+G  L          D  G 
Sbjct: 5125 APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGG 5181

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE----DRHWLLGESLHPDSLDRIGA 2755
              L I ++   D G+Y C A N +G + + A ++++    D       +         G 
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 2756 LXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI-HFECNVEPSRDPTLKIEWFFNNK 2814
            L                    +  L ++    G  +  F+  V+    P  ++ WF + +
Sbjct: 5242 LSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGY--PAPRLYWFKDGQ 5299

Query: 2815 PLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFD 2874
            PL +    + T      +L+I     EDSG Y    +N+ G+A +S  L   G       
Sbjct: 5300 PLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG------- 5352

Query: 2875 TQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQ 2934
               P+ K   +  EQ    R+ +   P     +  K    I  + +   VEG+ +     
Sbjct: 5353 PDEPEEKPASDVHEQLVPPRMLERFTP-----KKVKKGSSITFSVK---VEGRPVPTVHW 5404

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            +  + + +  + W     +      + + S     +L L+DV  +  G YTC A N  G+
Sbjct: 5405 L--REEAERGVLW-----IGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457

Query: 2995 AFTSSTVYCTSKDNLIER 3012
            A  S++++ +    + E+
Sbjct: 5458 ALCSASLHVSGLPKVEEQ 5475



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 42/159 (26%), Positives = 68/159 (42%), Gaps = 9/159 (5%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +   EVTW+ + +++    + K+ V   G    L++     +++G  +
Sbjct: 1641 GASATLSCEVA-QAQTEVTWYKDGKKLSS--SSKVRVEAVGCTRRLVVQQAGQAEAGEYS 1697

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A    G      RL V E E  ++ +   R   L V+E E ++L A         +TW
Sbjct: 1698 CEA----GGQQLSFRLQVAELEPQISERPCRR-EPLVVKEHEDIILTATLATPSAATVTW 1752

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             KDGV I  +      + G   TL +  A+  D+A Y C
Sbjct: 1753 LKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC 1791



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 83/425 (19%), Positives = 158/425 (37%), Gaps = 53/425 (12%)

Query: 4380 RKITSTETTEIEH---KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            R+  ST T  +     K+++  R+V   +    P + T+ ++P    E +      +F  
Sbjct: 2439 RRTCSTMTGPVHFTVGKSRSSARLVVSDI----PVVLTRPLEPKTGRELQSVVLSCDFRP 2494

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
             P   ++WY+++ P+  S  F++      + L I ++   D+ V+   A    G+A  S 
Sbjct: 2495 AP-KAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSST 2549

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             + VE +     G +         Q+   T         +++  +  +V W  NG  +  
Sbjct: 2550 EVTVEAREVTVTGPL---------QDAEATEEGWASFSCELS-HEDEEVEWSLNGMPLYN 2599

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
            D  ++I  +   +TL++      D+G     ++  +  AR +                  
Sbjct: 2600 DSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVRV--------------- 2644

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
                 P   ++ L D    E   +   C+ V  P   V W K    + PS  +    TA 
Sbjct: 2645 ----KPVVFLKALDDLSAEERGTLALQCE-VSDPEAHVVWRKDGVQLGPSDKYDFLHTAG 2699

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L + +  PED G Y C      G     A+++V       ++     L+ + V EG+
Sbjct: 2700 TRGLVVHDVSPEDAGLYTC----HVGSEETRARVRVHDL----HVGITKRLKTMEVLEGE 2751

Query: 4737 PAQFKTQIT-SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG--TFTC 4793
               F+  ++         W   G  +  +  FQ   +G   +L++      D G   F+ 
Sbjct: 2752 SCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSV 2811

Query: 4794 RATTA 4798
            R  T+
Sbjct: 2812 RGLTS 2816



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 37/136 (27%), Positives = 64/136 (47%), Gaps = 8/136 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND--FGF 3614
            PP F          E   A F C +       +R  W+ +G  L TG++ +T+++   G 
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
            ++L I    + D GLY C+  NR G A  S +L++   Q  +L+ Q   H +    +++ 
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLVAAVEV 6221

Query: 3675 LE-ETLHKREEITIED 3689
             E ET   ++ + IE+
Sbjct: 6222 TEQETKVPKKTVIIEE 6237



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            P+ +  P F T  K  + +  G  A    ++  +G+ T +V W KD +PV A +R     
Sbjct: 4    PQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQ 60

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            +     LTI  + + D+G Y CRA NAIG+A  +  L +  +     ++ H
Sbjct: 61   DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 111/485 (22%), Positives = 188/485 (38%), Gaps = 51/485 (10%)

Query: 922  KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
            +EGG A F+  + P   S + V W +DG  ++ S +     +    +LTI  + + DAG 
Sbjct: 1911 EEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ 1967

Query: 982  YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
             T  A  A    ++SA L +     +  +   P  +E+   +      + R   E++ T+
Sbjct: 1968 ITVEAEGA----SSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTR 2022

Query: 1042 KPRFLGPLKGTNKIVEG-------QSAHFEAR----VEPQSDLT---MTVEWYFNGKQIT 1087
                L P K      EG        +  F  R     E   D T   +TVE     +Q+ 
Sbjct: 2023 NATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM----RQVR 2078

Query: 1088 SANRIQTYH--DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSS 1145
                +Q     + G   +++    A+  G +T   R+     Q   +  +  R  + T +
Sbjct: 2079 LVRGLQAVEAREQGTATMEVQLSHADVDGSWT---RDGL-RFQQGPTCHLAVRGPMHTLT 2134

Query: 1146 IHRGLYEKTRHIEESKFVEPMYQIEEISKSKPV-FVQPLSNPPPVSEGKNIHLECRLEPM 1204
            +  GL  +   +   K          +    PV F +PL +    +E + + LEC L   
Sbjct: 2135 LS-GLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVV-TTEKEKVTLECELSR- 2191

Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264
              P + V W  +G  +  G            +L I     AD G Y   A  H   A +S
Sbjct: 2192 --PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDA--H--DAQSS 2245

Query: 1265 AIVRVIERS-DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP-QFSRALHNIET 1322
            A V+V  R+  ++      +   +IQ + + A    Q+R    V + P    R L +   
Sbjct: 2246 ASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLR----VKELPVTLVRPLRDKIA 2301

Query: 1323 VEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGV 1382
            +E     LEC+   V   + +V WF   + ++ G ++    +  Y  L +  V+ ED   
Sbjct: 2302 MEKHRGVLECQ---VSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDT 2358

Query: 1383 YTCQA 1387
            YTC A
Sbjct: 2359 YTCDA 2363



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--H 4460
            G +    PP F  K++     E E A+F    +G P P I+WY++   +     FQ    
Sbjct: 6100 GKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              S   +L+IR    ED  ++     NR G+A+ SA L ++    Q +
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQ 6207



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 763 EEQTSQRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           + Q S  P+F+ RP   +  +  G++A    Q+  V +PT +V W KD +P+ A +R   
Sbjct: 3   QPQFSGAPRFLTRPKAFV--VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRL 58

Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
             +     L I+ L   D+G Y  RA N +GEA +   ++V A +
Sbjct: 59  AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEA 103



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 5/98 (5%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FG 3338
            PP+F+ +++  +  VEG+ A F   +     P ++  W+ +G  L  G++++T  +   G
Sbjct: 6107 PPRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 6163

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
            +++L I    +E+ G YEC   N+LG     A L+  S
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND--FG 3751
            PPRF  +++ +  V EG    F C +E  G P  +I W+ +G    TG++  TL++   G
Sbjct: 6107 PPRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 6163

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + L I      D G Y C   N+ GSA  +A++
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAEL 6197



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 88/408 (21%), Positives = 146/408 (35%), Gaps = 57/408 (13%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++P  F + ++   V E   A           P +KW   N  ++    + +        
Sbjct: 3182 ARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLE 3240

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L++R +  +DS  ++       G    SA L V           +P  F    +N   T 
Sbjct: 3241 LVVRNLRPQDSGRYSCSF----GDQTTSATLTVTA---------LPAQFIGKLRNKEATE 3287

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ-DSGKYEC 4586
            G    L  +++   P++  W K G +   D     L +DG    L +      D+ +Y C
Sbjct: 3288 GATATLRCELSKAAPVE--WRK-GSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC 3344

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            V     GE R  A   +         +P       P   I  L+ +   EG      C++
Sbjct: 3345 VC----GEERTSASLTI---------RPM------PAHFIGRLRHQESIEGATATLRCEL 3385

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
              K  P V+W KG + ++      + +      L+I      D G+Y CV        T+
Sbjct: 3386 -SKAAP-VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATL 3443

Query: 4707 AAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
              K           LPA     LR+    EG  A    ++ SK+ P ++W +    + + 
Sbjct: 3444 TVKA----------LPAKFTEGLRNEEAVEGATAMLWCEL-SKVAP-VEWRKGPENLRDG 3491

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  EG    L I      D G + C      GQ  TSA L +++
Sbjct: 3492 DRYILRQEGTRCELQICGLAMADAGEYLC----VCGQERTSATLTIRA 3535



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 2/104 (1%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F+   K+     G       +I  VG+PT ++ W K+ Q + A +RF          L
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRL 67

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQH 740
            +L L + DSG+Y CRA +A G A     L V   A     + H
Sbjct: 68  TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 2/81 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            VS GK+  L C++  +G+PT +V W  + + V  G+RF+   D     L I+     D+G
Sbjct: 21   VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSG 78

Query: 1249 EYTVRAVNHLGSAHTSAIVRV 1269
            +Y  RA N +G A  +  ++V
Sbjct: 79   QYVCRARNAIGEAFAAVGLQV 99



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 57/230 (24%), Positives = 91/230 (39%), Gaps = 19/230 (8%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL--PSGTRYKSTHDFSYVSL 2833
            F+    +I  +EG    F C V  S  P   + W  + + L  P G R +        +L
Sbjct: 112  FLLRPTSIRVREGSEATFRCRVGGSPRPA--VSWSKDGRRLGEPDGPRVRVEELGEASAL 169

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             I      D G Y  +A N  G+A+ + +L    D             A L  +++  EA
Sbjct: 170  RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
              A+G   S P T                + EG+   L   V    +P  +  W  +G++
Sbjct: 230  MRAEGAPASPPSTG----------TRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQL 277

Query: 2954 LEQGSRFKLTSDF--GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + +G R  +  D    FV L ++   + D G+YTC A N  G+ ++S  V
Sbjct: 278  VTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 58/224 (25%), Positives = 95/224 (42%), Gaps = 20/224 (8%)

Query: 2242 PRFVTELRGTT-HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL--QSAARFHITFDFG 2298
            P F+  LR T+  V EG  A F C+V     P   + +  +G+ L      R  +  + G
Sbjct: 110  PHFL--LRPTSIRVREGSEATFRCRVGG--SPRPAVSWSKDGRRLGEPDGPRVRVE-ELG 164

Query: 2299 YVS-LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELE 2357
              S L I+   P D G Y V+A N LG  ++A ++ V +  +  +          +  L+
Sbjct: 165  EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ 224

Query: 2358 SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK 2417
                  R E   P +   P  T        + EG+ A   C +   G+P  +  W ++ +
Sbjct: 225  RRREAMRAE-GAPAS---PPSTG--TRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQ 276

Query: 2418 LIEDSSRITKTHDF--GYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            L+ +  R     D    +V + I   +  D G+Y C ASNL+G+
Sbjct: 277  LVTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQ 319



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 93/458 (20%), Positives = 173/458 (37%), Gaps = 54/458 (11%)

Query: 4362 VAKQKQTQKEVVG--DKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK--KM 4417
            ++   + + E VG   + + ++    E  E   +A  Q+      V   +P I  +  + 
Sbjct: 1666 LSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAELEPQISERPCRR 1725

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477
            +P  V EHE               + W ++   I+ S   +  +      L +    V D
Sbjct: 1726 EPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLD 1785

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            SA+++     R G       + VEE         V   F    + V    G  V L  ++
Sbjct: 1786 SAIYSC----RVGAEGQDFPVQVEE---------VAAKFCRLLEPVCGELGGTVTLACEL 1832

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
            +     +V W     +++   R +++ E    +L +L    +D+G+Y C     + +   
Sbjct: 1833 SPACA-EVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVC----ESRDDHT 1887

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             A+  VS+P                 + +  L   +  EG    F C +V      V W+
Sbjct: 1888 SAQLTVSVPRVV--------------KFMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWF 1932

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            +   L++PS+ F +S++   ++L IS+   ED G     A  ++     +A L+V +   
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASS----SAALRVRE--- 1985

Query: 4718 ADNLPAL--TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                P L    L    V E      + ++T +  P ++W R    +    + ++  EG  
Sbjct: 1986 ---APVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGAR 2041

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              L++ N    D G F C         +T AKL V+ +
Sbjct: 2042 HRLVLHNVGFADRGFFGCETP----DDKTQAKLTVEMR 2075



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 13/212 (6%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P  F  PL+ V   E  K+  E  +     P + + WLK+G  + A        +    S
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACRS 2221

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L +      D G Y C A  A   A  K V   T      R     E    IQ + + ++
Sbjct: 2222 LTIYRCEFADQGVYVCDAHDAQSSASVK-VQGRTYTLIYRRVL--AEDAGEIQFVAENAE 2278

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
             + Q  ++E        +RPL+D   +++ R    E Q   VS  + +V W+K  + +  
Sbjct: 2279 SRAQLRVKELP---VTLVRPLRDKIAMEKHRGV-LECQ---VSRASAQVRWFKGSQELQP 2331

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
              +   + +  Y  L I  + AED  +YT  A
Sbjct: 2332 GPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 10/161 (6%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +P  EVTW+ + +++    + K+ +   G    L++  V  +D+G  +
Sbjct: 1181 GTTAMLSCEVA-QPQTEVTWYKDGKKLSS--SSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A  +    +FQ  L++ E + V A + +   + +    G    L+       T  +TW
Sbjct: 1238 CEAGGQ--RVSFQ--LHITEPKAVFAKEQLVH-NEVRTEAGASATLSCEVAQAQT-EVTW 1291

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             KDG  +  + ++RI   G    L + +A  +DA  Y C A
Sbjct: 1292 YKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 8/137 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FG 2298
            PPRFV ++R +  V EG+ A F C +E    P +R  +Y +G  L +  +F    +   G
Sbjct: 6107 PPRFVNKVRASPFV-EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 6163

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL---EKIRE 2355
             + L I+    ED G Y  + +N LG   ++  + + +      E    E L    ++ E
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 6223

Query: 2356 LESAEPFKRPEIPEPVT 2372
             E+  P K   I E +T
Sbjct: 6224 QETKVPKKTVIIEETIT 6240



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 51/200 (25%), Positives = 75/200 (37%), Gaps = 14/200 (7%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR-FTPIYDF 4028
            +Q P F+ +  S       E T F C++   G P   V W  +G+ L   +     + + 
Sbjct: 107  EQAPHFLLRPTSIRVREGSEAT-FRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 4029 GYV-AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKI 4087
            G   A+      P D G Y  RA N  G     A +       +V         +     
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAAL-------VVDSDAADTASRPGTST 216

Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
              + A  Q   E +  E     PP   +     TV EG+ AR  C VTG PKP  +W  +
Sbjct: 217  AALLAHLQRRREAMRAEGAPASPPSTGTR--TCTVTEGKHARLSCYVTGEPKPETVWKKD 274

Query: 4148 GNTIVNGSRYKLTYDGMYHF 4167
            G  +  G R+ +  D   +F
Sbjct: 275  GQLVTEGRRHVVYEDAQENF 294



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 76/280 (27%), Positives = 111/280 (39%), Gaps = 31/280 (11%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKA--GSRFRTFCDF 3475
            +AP F +  ++I  +REG  A F  R+  +  P   V W  +G+ L    G R R     
Sbjct: 108  QAPHFLLRPTSIR-VREGSEATFRCRVGGSPRP--AVSWSKDGRRLGEPDGPRVRVEELG 164

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKI 3535
                L I    P D G Y  RA N  G A   A++ V        ++       GT    
Sbjct: 165  EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS------DAADTASRPGT-STA 217

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A L       + +  E    +PP  +T      ++E   A   C +    +      W  
Sbjct: 218  ALLAHLQRRREAMRAEGAPASPP--STGTRTCTVTEGKHARLSCYV--TGEPKPETVWKK 273

Query: 3596 NGKPLLTGSRVKTINDFGF-VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQG 3654
            +G+ +  G R     D     +L+I    Q D GLYTC A+N  G+ T S  L V     
Sbjct: 274  DGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-TYSSVLVV----- 327

Query: 3655 IILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNP 3694
             + EP +P  FK   + +Q LE  + ++E  T   E P P
Sbjct: 328  -VREPAVP--FK---KRLQDLE--VREKESATFLCEVPQP 359



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 67/288 (23%), Positives = 114/288 (39%), Gaps = 24/288 (8%)

Query: 2941 PDLKIEWYFNGKVLEQ--GSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P   + W  +G+ L +  G R ++        L +     RD G Y  +A N  G A  +
Sbjct: 137  PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
            + +   S  +  +    P GT     + +L+   R+    + +     PP   T      
Sbjct: 197  AALVVDS--DAADTASRP-GTSTAALLAHLQ---RRREAMRAEGAPASPPSTGT---RTC 247

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTT 3116
             ++EG+  H   S   TG+      W  +G+ +    R   VY  A    VL+IL  K +
Sbjct: 248  TVTEGK--HARLSCYVTGEPKPETVWKKDGQLVTEGRR-HVVYEDAQENFVLKILFCKQS 304

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G Y+C A+N  GQ   SV +   + +   K R    +Q++E +++ +SA F C    V
Sbjct: 305  DRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKR----LQDLE-VREKESATFLC---EV 356

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              P  +  W+     +  S +     +     L +      D   Y+C
Sbjct: 357  PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC 404



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 5/137 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--R 690
            V  PP+F+  +++   +EG    F   IE  G P  +I W K+G  +   ++F ++   R
Sbjct: 6104 VQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPR 6161

Query: 691  FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQHPETLQYIQQ 749
             G + L + + + +D G Y C  V+  G A   A L + +P    +      + +  ++ 
Sbjct: 6162 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEV 6221

Query: 750  LEDYSKYQHQESIEEQT 766
             E  +K   +  I E+T
Sbjct: 6222 TEQETKVPKKTVIIEET 6238



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 3/95 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F T  K++   V G+   L  Q+     P  ++ W K+   +  GAR +   D  L 
Sbjct: 9    APRFLTRPKAFVVSV-GKDATLSCQIVGNPTP--QVSWEKDQQPVAAGARFRLAQDGDLY 65

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             L+I  L   DSG Y C+A N +GEA +   ++++
Sbjct: 66   RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 73/320 (22%), Positives = 126/320 (39%), Gaps = 35/320 (10%)

Query: 2993 GEAFTSSTVY---CTSKDNLIERTQHPKGTEG--LEKIQN-LEDSLRKEPGQQPDDDTGR 3046
            G+A  +S+VY   C    + +   + P    G  L+ + N +E S+R E    P     +
Sbjct: 648  GQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANK 707

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPT-GDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP      ++++        H EA L+    DQ+  + W  +G+T+    +     + G 
Sbjct: 708  PP--AAAAREVL-----ARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGR 760

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
             VL +      D+G Y C   ++ G+    + ++ + +    K    + +  +     G 
Sbjct: 761  RVLLVRDVARDDAGLYEC--VSRGGRIAYQLSVQGLARFL-HKDMAGSCVDAVA----GG 813

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYT-QNHDSGEYVC 3224
             A FEC      +  + + WY +G  + HS       D G     +A T    D G Y C
Sbjct: 814  PAQFEC---ETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            R     GED     +       V+ +    + LA+ R+L++  GA   T S   A+    
Sbjct: 871  RV----GEDSVDFRLRVSEPKVVFAK----EQLAR-RKLQAEAGA-SATLSCEVAQAQTE 920

Query: 3285 ITQIQDVTKLVEGQSAHFEA 3304
            +T  +D  KL        EA
Sbjct: 921  VTWYKDGKKLSSSSKVCMEA 940



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 12/163 (7%)

Query: 1701 SAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            S   +++ Q P  F   ++     E + A F   +   G P  ++ W ++G  +   N+ 
Sbjct: 6097 STLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKF 6154

Query: 1760 TTMHD--FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH-ES 1816
             T+ +   G + L ++  + ED G Y C  +N LG A  S+ L +QS      E  H E 
Sbjct: 6155 QTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQ 6214

Query: 1817 ALQKIQQLEDSSRYQRR----EDVEVAVNQAPRFITQLNGPTK 1855
             +  ++  E  ++  ++    E+    V ++PR   Q   P+K
Sbjct: 6215 LVAAVEVTEQETKVPKKTVIIEETITTVVKSPR--GQRRSPSK 6255



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 50/198 (25%), Positives = 77/198 (38%), Gaps = 9/198 (4%)

Query: 2007 PTMRVEWYCNGRPVQQ--GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            P   V W  +GR + +  G R +        AL I  A   D GTY  +A N +G A   
Sbjct: 137  PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196

Query: 2065 SSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEG 2124
            +++ VD+ +              +  L++  R     E  P   P   +  T    + EG
Sbjct: 197  AALVVDSDAADTASRPGTSTAALLAHLQR-RREAMRAEGAPASPP---STGTRTCTVTEG 252

Query: 2125 DRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY-VALDILYTYAEDSGTYM 2183
              A   C V    +P     W  +GQ +  G R+    D      L IL+    D G Y 
Sbjct: 253  KHARLSCYVT--GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYT 310

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C A+N +G+  ++  + V
Sbjct: 311  CTASNLVGQTYSSVLVVV 328



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 4/147 (2%)

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
            D+ T    + ++++  +   AA +  +VR+++   + P FS    + E   G  + LEC 
Sbjct: 4861 DLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECV 4920

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTG-HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            +    D  +R  W  +G  +  G H           +L +  +   D+G YTCQ +N+ G
Sbjct: 4921 VASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFG 4978

Query: 1393 EAVTSCALRVIAKKDLILESQHPSGLE 1419
            + VT  A  V++  +   ES     L+
Sbjct: 4979 Q-VTHSACVVVSGSESEAESSSGGELD 5004



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            +++ Q    P FLT   +   +  G  A   C++  + +P   + W  + Q + AG R+R
Sbjct: 1    MDQPQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFR 57

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               D     L IL     DSG Y+C+A N +GEA     L+V
Sbjct: 58   LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 58/269 (21%), Positives = 102/269 (37%), Gaps = 33/269 (12%)

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  V W K+   + P  + K+  E     L IL   P D+G Y C     AG A    E 
Sbjct: 2496 PKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC----QAGSAHSSTEV 2551

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V                     +  PL+D    E     FSC++  +    V+W     
Sbjct: 2552 TVEAREV---------------TVTGPLQDAEATEEGWASFSCELSHED-EEVEWSLNGM 2595

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +    + ++S     +TL +      D G    +   S+ +V+ +A+L+V    +   +
Sbjct: 2596 PLYNDSFHEISHKGRRHTLVLKSIQRADAG----IVRASSLKVSTSARLEV----RVKPV 2647

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L  L D+   E      + ++ S  +  + W ++G  +  +  +  +H      L++ 
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVH 2706

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED G +TC      G  ET A++ V
Sbjct: 2707 DVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 15/187 (8%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F++  Q ++V EG      C ++ R    V W     Q+     ++ +V +     L++
Sbjct: 3980 RFLRELQHQEVDEGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQ-MVQDGAAAELLV 4037

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
              V   D+G  TC     +G T     L+V    +V  PKF  R  +L    G+   L  
Sbjct: 4038 RGVEQEDAGDYTC----DTGHTQSMASLSV----RVPRPKFKTRLQSLEQETGDIARLCC 4089

Query: 513  RAVGTPTPRIT-WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +     +  +  W K+GV +   P+  + + G    L I + +A D   Y C    V G 
Sbjct: 4090 QLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC----VTGG 4145

Query: 572  TATRARL 578
              T A L
Sbjct: 4146 QKTAASL 4152



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 8/101 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL------VECNKYSMRYNE 124
            PP   + F   +  +G +  F  K+ G P P V W R++A         +   Y++  + 
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
            Q    SL++  +G   +G YTC A N  G+A+CS  +   G
Sbjct: 5430 QQH--SLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSG 5468



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 64/239 (26%), Positives = 88/239 (36%), Gaps = 22/239 (9%)

Query: 768  QRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI-TASSRITSIFNF 825
            Q P F+ RP      ++EG  A F  ++     P   V W KDGR +         +   
Sbjct: 108  QAPHFLLRPTSI--RVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 826  GYVS-LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKT 884
            G  S L I   R  D G+Y VRA N LG A + A++ V + +  TA       R      
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTAS------RPGTSTA 217

Query: 885  XXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVE 944
                              P S      +T      ++ EG  A     +   G+      
Sbjct: 218  ALLAHLQRRREAMRAEGAPASPPSTGTRT-----CTVTEGKHARLSCYVT--GEPKPETV 270

Query: 945  WLKDGRPVEASSRITTFFNFGY-VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG+ V    R   + +      L I      D G YTC A N +GQ T S+ L +V
Sbjct: 271  WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-TYSSVLVVV 328



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 3/90 (3%)

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            SA+ EV  +  VF   + D+   E      +     V DP+  V W ++GV +  S++  
Sbjct: 2637 SARLEVRVKPVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYD 2693

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
             +H  G   L +  V+PED+G YTC   +E
Sbjct: 2694 FLHTAGTRGLVVHDVSPEDAGLYTCHVGSE 2723



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSG 3491
            EGE+A F   +     P ++  WY +G  L  G++F+T  +   G ++L I     ED G
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 3492 EYLCRAYNNYGEAVTTASMKVQ 3513
             Y C   N  G A  +A +++Q
Sbjct: 6179 LYECELVNRLGSARASAELRIQ 6200



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 54/215 (25%), Positives = 87/215 (40%), Gaps = 12/215 (5%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            VT  P   +RP       E + V  EC+L   +  N+ V W K+G  +  G         
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQG 2217

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559
               +L I      D G+Y C A +       S ++  R+ T I R    E   E IQ + 
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHD--AQSSASVKVQGRTYTLIYRRVLAEDAGE-IQFVA 2274

Query: 1560 DRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKP 1619
            + ++      V E+    P+  T ++ +  K     H       VS A+ +V W+  ++ 
Sbjct: 2275 ENAESRAQLRVKEL----PV--TLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQE 2328

Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
            L+ G ++   ++  +  L I     ED  TYTC A
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 56/237 (23%), Positives = 95/237 (40%), Gaps = 21/237 (8%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++V  E + +  EC  E SR P + + W  +   L +G         +  SL I
Sbjct: 2168 FSRPLQDVVTTEKEKVTLEC--ELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                  D G+Y C A +++ SA+     R      + +     +    ++ V +  E+R 
Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQGRTY---TLIYRRVLAEDAGEIQFVAENAESR- 2280

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLE 2955
            A+ R   +P T        I +     ++E QV     QV           W+   + L+
Sbjct: 2281 AQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVR----------WFKGSQELQ 2330

Query: 2956 QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
             G +++L SD  +  L + DV+  D   YTC A    G+  TS+  +   +   I R
Sbjct: 2331 PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEEQSITIVR 2383



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ +   PRF+  ++ +   VEG+ A F   +E        + WY +G  +T+ N+ QT 
Sbjct: 6101 KILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAP--YPQIRWYKDGALLTTGNKFQTL 6157

Query: 1096 HD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             +   G + L I +   ED G+Y     N  G A+ SA + +++         HR
Sbjct: 6158 SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 6212



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/112 (26%), Positives = 57/112 (50%), Gaps = 4/112 (3%)

Query: 2234 VEEPKIS-PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292
            +++P+ S  PRF+T  +    V  GK A   CQ+  V +P  ++ +  + + + + ARF 
Sbjct: 1    MDQPQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFR 57

Query: 2293 ITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344
            +  D     L I      D+G+Y  +A NA+G   +A+ + V A+ +   ++
Sbjct: 58   LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA 109



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            PRF    K  + V  G      C++  VG+PT ++ W  + +P A G+R     D     
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            L I  +   D+G+Y CRA N  G A     +   A+
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 18/195 (9%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            ++ +AL  +F++  ++++  EG      C ++ +  P V W      +R    + +   +
Sbjct: 3795 LTVRALPARFIEDVKNQEAREGATAVLQCELS-KAAP-VEWRKGSETLRGGDRYSL--RQ 3850

Query: 445  SGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
             G    L I  ++++D+G  +CV     G+      L V    +   P F E   +L   
Sbjct: 3851 DGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTV----RAPQPVFREPLQSLQAE 3902

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            EG    L    +  PT  + W K G+ +  N        G  + L +   +  D   Y C
Sbjct: 3903 EGSTATLQCE-LSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC 3961

Query: 564  TAQNVAGSTATRARL 578
            T     GS AT A L
Sbjct: 3962 T----CGSQATSATL 3972



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/92 (28%), Positives = 43/92 (46%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F    + + F +G +A+F   + G P P + W +  A L   NK+      ++G + 
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 6166

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            L+I+     D G Y C   N+ G A  S  ++
Sbjct: 6167 LVIRAASKEDLGLYECELVNRLGSARASAELR 6198



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSG 2180
            EG+ A F C +E    P+  I W+ +G  +  G++++T  +   G + L I     ED G
Sbjct: 6121 EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
             Y C+  N+LG A  +  L++
Sbjct: 6179 LYECELVNRLGSARASAELRI 6199



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F    K   V+  + A    ++  VG+P  +V W ++  P+ A  R     D     
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814
            L +  +   DSG Y CRA N +GEA  +  L V ++A+   ++ H
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 56/218 (25%), Positives = 79/218 (36%), Gaps = 13/218 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKM--GSRFRTTHDFGFVTLDINSVVANDAG 2579
            EG  A +  RV   G P     W  +G  L    G R R         L I +    D G
Sbjct: 123  EGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG 180

Query: 2580 LYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQ 2639
             Y  +A N  G                 D A RP +     L  A + +  E     G  
Sbjct: 181  TYEVRAENPLGAASAAAALVVDSDAA--DTASRPGTSTAALL--AHLQRRREAMRAEGAP 236

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
             +P  T        + EG+H  L   V    +P  +  W K+G  +T G R     D   
Sbjct: 237  ASPPSTGTRTC--TVTEGKHARLSCYVTG--EPKPETVWKKDGQLVTEGRRHVVYEDAQE 292

Query: 2700 -VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               L I   +  D G+YTC A+NL+G+  S+  + + +
Sbjct: 293  NFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 58/217 (26%), Positives = 97/217 (44%), Gaps = 28/217 (12%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA---NL 999
            V WLKDG  + A   +         +LTI      D G Y C A++A   A+        
Sbjct: 2196 VRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTY 2255

Query: 1000 TIVTKKDIIAESQHPGGLEKIQYL-EDASRYSKRTEEEVKITQKPRFLGPLKGTNKI-VE 1057
            T++ ++ ++AE        +IQ++ E+A   ++   +E+ +T     + PL+  +KI +E
Sbjct: 2256 TLIYRR-VLAED-----AGEIQFVAENAESRAQLRVKELPVT----LVRPLR--DKIAME 2303

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
                  E +V   S  +  V W+   +++    + +   D  Y  L I+ V AED   YT
Sbjct: 2304 KHRGVLECQV---SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYT 2360

Query: 1118 VVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKT 1154
                  AG+ + SA   VE +S     +I RGL + T
Sbjct: 2361 C----DAGDVKTSAQFFVEEQS----ITIVRGLQDVT 2389



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP   T  K   +  G+ A    ++  V + T +V W  + +P+ +G+RF    +     
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEA 1661
            L I+     DSG Y CRA NA+GEA
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEA 91



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 43/198 (21%), Positives = 81/198 (40%), Gaps = 11/198 (5%)

Query: 370  YITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            Y  + + +    R+ I+E K +  +   V  +     G      C V  +   EVTW+ +
Sbjct: 1052 YSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVA-QAQTEVTWYKD 1110

Query: 429  DRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
             +++    + K+ +   G    L++     +D+G  +C A    G       L++ E + 
Sbjct: 1111 GKKLSS--SSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA----GGQRVSFHLHITEPKG 1164

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
            V A K     + +    G   +L+   V  P   +TW KDG  +  + ++R+   G    
Sbjct: 1165 VFA-KEQSVHNEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRR 1222

Query: 548  LDIPRAKASDAAWYQCTA 565
            L + +   +DA  Y C A
Sbjct: 1223 LVVQQVGKADAGEYSCEA 1240



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 41/199 (20%), Positives = 81/199 (40%), Gaps = 11/199 (5%)

Query: 369  QYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            +Y  +   +     + ++E KA+  +     ++     G      C V  +   EVTW+ 
Sbjct: 1511 EYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTEVTWYK 1569

Query: 428  NDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
            + +++    + K+ +   G    L++     +D+G  +C    K+G+      L+V E +
Sbjct: 1570 DGKKLSS--SSKVRMEAVGCTRRLVVQEAGQADAGEYSC----KAGDQRLSFHLHVAEPK 1623

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
             V A K       +    G    L+       T  +TW KDG  +  + ++R+   G   
Sbjct: 1624 VVFA-KEQPAHREVQAEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRVEAVGCTR 1681

Query: 547  TLDIPRAKASDAAWYQCTA 565
             L + +A  ++A  Y C A
Sbjct: 1682 RLVVQQAGQAEAGEYSCEA 1700



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 55/235 (23%), Positives = 98/235 (41%), Gaps = 15/235 (6%)

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            L   P   +V+ G       ++ + +D+ + Y  D    +T  +  + E+++    V+  
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDT-YTCDAGDVKTSAQFFVEEQSIT--IVRGL 2385

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            QD  V E     F+C  +        W +    ++   N   L  E   H LM+     +
Sbjct: 2386 QDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVG-LEQEGTVHRLMLRRTCST 2444

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
             +G V        G++    RL V+    VV  + +E  +    RE + VVL+      P
Sbjct: 2445 MTGPVHFTV----GKSRSSARL-VVSDIPVVLTRPLEPKTG---RELQSVVLSCDF--RP 2494

Query: 519  TPR-ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P+ + W KD  P+ P+ + ++  +G  + L I R   +DA  Y+C A +   ST
Sbjct: 2495 APKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSST 2549



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-F 691
            V+ PP F   L   TA  G  +    R+   G P   I W K+G++++       I    
Sbjct: 6010 VWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPD 6067

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
            G  +L + SL   DSG+Y C A SA G   T  K ++ V PR
Sbjct: 6068 GSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPR 6109



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P F++ P A  V  G+ A   C++ G+P P+V W  +   +  G+R++L  DG +Y   I
Sbjct: 10   PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 4170 PKTRQYDTGK 4179
                  D+G+
Sbjct: 70   LDLALGDSGQ 79



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 54/238 (22%), Positives = 94/238 (39%), Gaps = 23/238 (9%)

Query: 1573 VTTQAPIC-TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631
            V T+ P+  +  L++V   E ++   E  L   S   + V W  +   L++G        
Sbjct: 2160 VVTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQ 2216

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691
                +L I  C   D G Y C A +A             S  S+ ++ +    + R    
Sbjct: 2217 GACRSLTIYRCEFADQGVYVCDAHDA------------QSSASVKVQGRTYTLIYRRVLA 2264

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLI---PVGDPKLRVEWLR 1748
            ED  + Q  +   E   Q  V  +P+  +R   ++ A  + R +    V     +V W +
Sbjct: 2265 EDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFK 2324

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
                ++   +   + D  Y  L +  V+ ED  TYTC A    G+  TS+  FV+ ++
Sbjct: 2325 GSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEEQS 2378



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/350 (21%), Positives = 129/350 (36%), Gaps = 24/350 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P  +TRP   +   E Q V   C   P   +   V+W+K+  P++   +F+   +     
Sbjct: 2468 PVVLTRPLEPKTGRELQSVVLSCDFRPAPKA---VQWYKDDTPLSPSEKFKMSLEGQMAE 2524

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L I+ L+  D+G+Y C+A +   + EV+  +  R  T +    Q+    E+         
Sbjct: 2525 LRILRLMPADAGVYRCQAGSAHSSTEVT--VEAREVT-VTGPLQDAEATEEGWASFSCEL 2581

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
             H  + V+      P+   S   +  K G+R     + I  +DA   +    + K   S 
Sbjct: 2582 SHEDEEVEWSLNGMPLYNDSFHEISHK-GRRHTLVLKSIQRADA--GIVRASSLKVSTSA 2638

Query: 1624 SRFTETNNFGFV-ALDIMSCLPEDSGTYTCRAINALGEAV--TSGIAIVHSKKSIYLESQ 1680
                      F+ ALD +S     +    C   +     V    G+ +  S K  +L + 
Sbjct: 2639 RLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTA 2698

Query: 1681 -HEGALPRLNQLEDTSKYQRHSAQDEVITQAPV------FTMPMKDIRVAENQAAHFEAR 1733
               G +      ED   Y  H   +E   +  V       T  +K + V E ++  FE  
Sbjct: 2699 GTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECV 2758

Query: 1734 LI--PVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSG 1781
            L      DP +   W   G  + +S+R           L ++   P D+G
Sbjct: 2759 LSHESASDPAM---WTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG 2805



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F    +N     G    F+  + G P P V W  K   L+E + + M   +Q G   L
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWF-KDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 132  LIKQIGPGDEGEYTCTARNQYG 153
            +I  + P D G Y C A N  G
Sbjct: 5185 IITAVVPADMGVYRCLAENSMG 5206



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 98/470 (20%), Positives = 184/470 (39%), Gaps = 65/470 (13%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            V+W +    L   +K  M     T    L++ Q G  D GEY+C A  Q       +  +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTR--RLVLPQAGKADAGEYSCEAGGQRVSFHLHI-TE 1161

Query: 163  PEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR-QTQKVAYTNGTDHSSTDDF 221
            P+G              + V   V+ +A  T   + E ++ QT+   Y +G   SS+   
Sbjct: 1162 PKGVFAKE---------QSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKV 1212

Query: 222  KVDTFEYRLLREVSFRESITKRYVGESDVQISTE-IDRSLGPVSPPKIAQKPR----NSK 276
            +++       R +  ++ + K   GE   +   + +   L    P  +  K +      +
Sbjct: 1213 RMEV--KGCTRRLVVQQ-VGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVR 1269

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             + GA A    +++   +  VTW+K+G++L +S+K  I        L V+   ++D+G Y
Sbjct: 1270 TEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T  A    G    S +L V  P   + ++Q +             +++    A+A    +
Sbjct: 1329 TCEA----GGQRLSFHLDVSEPKAVFAKEQLA-----------HRKVQAEAGAIATLSCE 1373

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNV 455
            V Q +  TE                 VTW+ + +++    + K+ +   G    L++   
Sbjct: 1374 VAQAQ--TE-----------------VTWYKDGKKLSS--SSKVRMEAVGCTRRLVVQQA 1412

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
              +D+G  +C    ++G       L+V E  +VV  K       +  + G    L+    
Sbjct: 1413 CQADTGEYSC----EAGGQRLSFSLDVAE-PKVVFAKEQPVHREVQAQAGASTTLSCEVA 1467

Query: 516  GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
               T  + W KDG  +  + ++R+   G    L + +A  + A  Y C A
Sbjct: 1468 QAQT-EVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA 1516



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 113/481 (23%), Positives = 190/481 (39%), Gaps = 51/481 (10%)

Query: 1998 EATLTPVNDPT-MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
            EAT   V  P+ + V W+ +G  +Q   +F  +      +L I     ED G    +A  
Sbjct: 1915 EATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG 1974

Query: 2057 AVGEA-VTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKP-------IEEEQPGQR 2108
            A   A +      V  K  L   T++E R     E+E   RP P            PG+ 
Sbjct: 1975 ASSSAALRVREAPVLFKKKLEPQTVEE-RSSVTLEVE-LTRPWPELRWTRNATALAPGKN 2032

Query: 2109 PVFLTALTS-----LENLKEGDRAHFECRV-EPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
             V + A  +     L N+   DR  F C   +      LT++      ++  G +     
Sbjct: 2033 -VEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM--RQVRLVRGLQAVEAR 2089

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII-LDTQHP--NGLEK 2219
            + G   +++  ++A+  G++         +   TC L V G  + + L    P  +GL  
Sbjct: 2090 EQGTATMEVQLSHADVDGSWTRDGLRF--QQGPTCHLAVRGPMHTLTLSGLRPEDSGL-M 2146

Query: 2220 IRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
            + + E    S R+ V E  +S  R + ++  T    E +    EC++     PN+ + + 
Sbjct: 2147 VFKAEGVHTSARLVVTELPVSFSRPLQDVVTT----EKEKVTLECELSR---PNVDVRWL 2199

Query: 2280 HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKG- 2338
             +G  L++     I       SL I  C   D G Y   A +A     S+ S+ V  +  
Sbjct: 2200 KDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTY 2255

Query: 2339 SIISESQRPEGLEKIREL-ESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNI-QEGQTAH 2395
            ++I      E   +I+ + E+AE   +  + E PVT  RP+        D I  E     
Sbjct: 2256 TLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLR-------DKIAMEKHRGV 2308

Query: 2396 FDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
             +C+   V   + +V WF+  + ++   +     D  Y  + IS V  EDE  Y C A +
Sbjct: 2309 LECQ---VSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD 2365

Query: 2456 L 2456
            +
Sbjct: 2366 V 2366



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 8/109 (7%)

Query: 635  PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            P P F  PL+S+ A EG     +  +    +PT  + W K G  ++A+ R     +    
Sbjct: 3888 PQPVFREPLQSLQAEEGSTATLQCELS---EPTATVVWSKGGLQLQANGRREPRLQGCTA 3944

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR-ATIERTSQHPE 742
             L +  L  +D+GEYTC      G   T A L VT       R  QH E
Sbjct: 3945 ELVLQDLQREDTGEYTC----TCGSQATSATLTVTAAPVRFLRELQHQE 3989



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN--FGY 827
            P+F+  ++      EG +A F   +     P +R  WYKDG  +T  ++  ++     G 
Sbjct: 6108 PRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            + L I     ED G Y    VN+LG A ++A +R+
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 10/120 (8%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            AA +GY      +  E +    P F+ T  D       +   EC  +  + + +R  W  
Sbjct: 4881 AAFKGYK-----VRKEMKQQEGPMFSHTFGDTEAQVGDALRLEC--VVASKADVRARWLK 4933

Query: 3596 NGKPLLTGSR--VKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G  L  G    +  + D G   L I G+ + DAG YTC+ +N+ G+ T S  + V G +
Sbjct: 4934 DGVELTDGRHHHIDQLGD-GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSE 4992



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 2/72 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +  G+ A   C++  VG+PT +V W ++++ +   +R     D     +TI  +   D G
Sbjct: 21   VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSG 78

Query: 2448 VYMCRASNLLGE 2459
             Y+CRA N +GE
Sbjct: 79   QYVCRARNAIGE 90



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/76 (28%), Positives = 39/76 (51%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            +P  ++ W  + + +  G+RF+L  D     L ++D+   DSG Y C+A N  GEAF + 
Sbjct: 36   NPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95

Query: 3000 TVYCTSKDNLIERTQH 3015
             +   ++    E+  H
Sbjct: 96   GLQVDAEAACAEQAPH 111



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN------FPIKNSPDFQIHTFS 4463
            PP   ++  P +V +     F V+ +G P+P + W RE       +   ++P + + + +
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +  L++  V  +    +  +A N  G A CSA+L V
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 4/124 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYV 2035
            P+F   ++ +   EG       T+     P +R  WY +G  +  G++F+T  +   G +
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLL 6165

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L I  A  ED G Y C+  N +G A  ++ +++ +      +    ++L    E+ + E
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQE 6225

Query: 2096 RPKP 2099
               P
Sbjct: 6226 TKVP 6229



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R         L +      D+G YSC A    G   +S +L   
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSFQLHIT 1252

Query: 3142 D-KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            + K+   K +    + N    + G SA   C V        ++ WY +G+ +  S++++ 
Sbjct: 1253 EPKAVFAKEQL---VHNEVRTEAGASATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRI 1306

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             +      L +      D+GEY C A
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 9/156 (5%)

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            EV W   + Q+R     + +V E    +L +  +   D+G   C +R+    T+ Q  ++
Sbjct: 1838 EVVWRCGNTQLRVGKRFQ-MVAEGPVRSLTVLGLRAEDAGEYVCESRDD--HTSAQLTVS 1894

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V    +VV  KF+   ST+   EG         V      + W +DG  + P+ +  I  
Sbjct: 1895 V---PRVV--KFMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQ 1948

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
             G + +L I      DA      A+  + S A R R
Sbjct: 1949 SGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDF 2697
            Q+ P+F+ H     +   G  + LE  V  + D  ++  W K+GV LT G          
Sbjct: 4895 QEGPMFS-HTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD 4951

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  +L I  L   D+G YTC+ +N  G+   +A + +
Sbjct: 4952 GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 66/294 (22%), Positives = 104/294 (35%), Gaps = 34/294 (11%)

Query: 82  RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGD 140
           R  +G  A F  ++ G+P P VSW++    L E +   +R  E+ G+ S L I+   P D
Sbjct: 120 RVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRV-EELGEASALRIRAARPRD 178

Query: 141 EGEYTCTARNQYGEAICSVYIQPEGXXXXXXX---XXXXXXYRHVSETVE---------- 187
            G Y   A N  G A  +  +  +                   H+    E          
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPAS 238

Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSST---DDFKV-----------DTFEYRLLRE 233
             + GT+  T  + +  +   Y  G     T    D ++           D  E  +L+ 
Sbjct: 239 PPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKI 298

Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSG 291
           +  ++S    Y   +   +       L  V  P +  K R  + +++E   A F  ++  
Sbjct: 299 LFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVP- 357

Query: 292 NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            P     WFK   RL  S K+ I        L VRN    D   Y  + E P G
Sbjct: 358 QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVY--ICETPEG 409



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 80/375 (21%), Positives = 141/375 (37%), Gaps = 44/375 (11%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S   ++        L++++    D+  ++  A    G  + S +L V 
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVA 1620

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E +      +V        + V   +G    L  +V   +  +V W K+GKK+    + +
Sbjct: 1621 EPK------VVFAKEQPAHREVQAEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVR 1673

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL-PATKDKPKPQTKAAN 4620
            +     T  L++ +A   ++G+Y C A    G+       V  L P   ++P  +     
Sbjct: 1674 VEAVGCTRRLVVQQAGQAEAGEYSCEA---GGQQLSFRLQVAELEPQISERPCRR----- 1725

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
                  EPL   +V E + I  +  +      TV W K    I+ SK  + +   D +TL
Sbjct: 1726 ------EPL---VVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTL 1776

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYE-GQPA 4738
             +  A   D   Y C       RV    +     P Q + + A    L + V  E G   
Sbjct: 1777 TVHGAQVLDSAIYSC-------RVGAEGQ---DFPVQVEEVAAKFCRLLEPVCGELGGTV 1826

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC--RAT 4796
                +++      + W      +     FQM+ EG    L +     ED G + C  R  
Sbjct: 1827 TLACELSPACAEVV-WRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDD 1885

Query: 4797 TAAGQVETSAKLVVK 4811
              + Q+  S   VVK
Sbjct: 1886 HTSAQLTVSVPRVVK 1900



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            R    + V+  P  +T+   P    E QS    C   P P     V+WY +   L    +
Sbjct: 2457 RSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKA---VQWYKDDTPLSPSEK 2513

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++ S +   A L IL +   D+G Y C+A    G A SS  + V+++E
Sbjct: 2514 FKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVEARE 2557



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFV 3887
            PP F  ++   T E  E V+  CRV     PK  I WY++GK +     +  + D  G  
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 6070

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +L +  +   DSG+Y+C A +  G   T   I  +  P  +
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFV 6111



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP FE+   +     G   K   ++ G P PV+SW  K    V+ + + +   +  G  +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISW-YKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 131  LLIKQIGPGDEGEYTCTARNQYG 153
            L++  +   D G+Y C A +  G
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAG 6094



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EG++  F C +E +  P  +I W+ +   L +G ++++  +     + L I    +ED G
Sbjct: 6121 EGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2845 IYTCKATNSKGSATTSGSLR 2864
            +Y C+  N  GSA  S  LR
Sbjct: 6179 LYECELVNRLGSARASAELR 6198



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/67 (34%), Positives = 34/67 (50%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            +P  +V W  + + + AG+RFR   D     L I      DSG+Y+CRA N  GEA    
Sbjct: 36   NPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95

Query: 3509 SMKVQGK 3515
             ++V  +
Sbjct: 96   GLQVDAE 102



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG+ A +   +     P +R  WY +G  L  G++F+T  +   G + L I +    D G
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2580 LYMCKAINRAG 2590
            LY C+ +NR G
Sbjct: 6179 LYECELVNRLG 6189



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 145/671 (21%), Positives = 247/671 (36%), Gaps = 71/671 (10%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            +S    V  +PL  P    E +++ L C   P       V+W+ +   ++   +FK   +
Sbjct: 2464 VSDIPVVLTRPLE-PKTGRELQSVVLSCDFRPA---PKAVQWYKDDTPLSPSEKFKMSLE 2519

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT-DTQNEQAIEQ--I 1288
                 L I+    AD G Y  +A    GSAH+S  V V  R   VT   Q+ +A E+   
Sbjct: 2520 GQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWA 2575

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
                + +   ++V   +  M  P ++ + H I      +  +   +Q      +R     
Sbjct: 2576 SFSCELSHEDEEVEWSLNGM--PLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLK 2633

Query: 1349 NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN------------QLGEAVT 1396
                 +   R +P       ALD LS     +    C+ ++            QLG +  
Sbjct: 2634 VSTSARLEVRVKPVVFLK--ALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDK 2691

Query: 1397 SCALRVIAKKDLILESQHP--SGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIE 1454
               L     + L++    P  +GL       + +R  +  + D  V I  R     K++E
Sbjct: 2692 YDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETR-ARVRVHDLHVGITKRL----KTME 2746

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
             V+EG+   FEC L   + S+    W   G+ V    RF+         L + +    D+
Sbjct: 2747 -VLEGESCSFECVLSHESASD-PAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDA 2804

Query: 1515 G--IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDE 1572
            G  +++ R +    T + S  L  R     +     +  +   + +E R +  R      
Sbjct: 2805 GEVVFSVRGL----TSKAS--LIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVH 2858

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
                      S K   + EG  A    R   + DA    E+    +  KS +        
Sbjct: 2859 WLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAG---EYTCEVEASKSTASLHVEEKA 2915

Query: 1633 GFVALDIMSCLPEDSGT--YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRL-- 1688
                 ++ +   E+ GT  +TC+  +     VT    ++  + S   +   EG   RL  
Sbjct: 2916 NCFTEELTNLQVEEKGTAVFTCKTEHP-AATVTWRKGLLELRASGKHQPSQEGLTLRLTI 2974

Query: 1689 NQLE--DTSKYQRHSAQDEVITQAPV------FTMPMKDIRVAENQAAHFEARLIPVG-D 1739
            + LE  D+  Y     Q +   Q  V          ++D+ V E  +A F  R+ P   +
Sbjct: 2975 SALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYE 3034

Query: 1740 PKLRVEWLRNGVPIEASNRLTTM--HDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            P   V W  +  P+ A N L  +     GY  L ++ +  +DSGT       E G+   S
Sbjct: 3035 P---VHWFLDKTPLHA-NELNEIDAQPGGYHVLTLRQLALKDSGT----IYFEAGDQRAS 3086

Query: 1798 STLFVQSKASL 1808
            + L V  K S+
Sbjct: 3087 AALRVTEKPSV 3097



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 56/243 (23%), Positives = 94/243 (38%), Gaps = 23/243 (9%)

Query: 99   PTP-VVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
            P P  V W +   PL    K+ M    Q  ++ +L  ++ P D G Y C A    G A  
Sbjct: 2494 PAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRIL--RLMPADAGVYRCQA----GSAHS 2547

Query: 158  SVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSS 217
            S  +  E                  +E  E    G   ++ E S + ++V ++       
Sbjct: 2548 STEVTVEAREVTVTGPLQD------AEATEE---GWASFSCELSHEDEEVEWSLNGMPLY 2598

Query: 218  TDDFKVDTFEYRLLREVSFRESITKRYVG---ESDVQISTEIDRSLGPVSPPKIAQKPRN 274
             D F   + + R  R     +SI +   G    S +++ST     +  V P    +   +
Sbjct: 2599 NDSFHEISHKGR--RHTLVLKSIQRADAGIVRASSLKVSTSARLEVR-VKPVVFLKALDD 2655

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
               +E      Q ++S +P   V W K+G +L  S+K++ + T     L V +    D+G
Sbjct: 2656 LSAEERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAG 2714

Query: 335  HYT 337
             YT
Sbjct: 2715 LYT 2717



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/162 (22%), Positives = 66/162 (40%), Gaps = 10/162 (6%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +   EVTW+ + +++    + K+ +  +G    L++     +D+G  +
Sbjct: 905  GASATLSCEVA-QAQTEVTWYKDGKKLSS--SSKVCMEATGCTRRLVVQQAGQADAGEYS 961

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A    G       L+V E + V A   V   S +    G    L+       T  + W
Sbjct: 962  CEA----GGQRLSFHLDVKEPKVVFAKDQVAH-SEVQAEAGASATLSCEVAQAQT-EVMW 1015

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
             KDG  +  + ++ +   G    L + +A  +DA  Y C A+
Sbjct: 1016 YKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEAR 1057



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 82/367 (22%), Positives = 142/367 (38%), Gaps = 35/367 (9%)

Query: 1471 VTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEV 1530
            V+D    V W K+G  +    ++  +H  G   L + D+  ED+G+YTC     VG++E 
Sbjct: 2670 VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEET 2725

Query: 1531 SCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNV--- 1587
              R+        V  T+    L+ ++VLE  S      +  E  +   + T   K V   
Sbjct: 2726 RARVRVHDLH--VGITKR---LKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSS 2780

Query: 1588 ----EIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
                  ++G++     R    SDA  +V +       K+     E        L+     
Sbjct: 2781 SRFQATRQGRKYILVVREAAPSDAG-EVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVA 2839

Query: 1644 PEDSGTYTCRAINALGEAV---TSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKY-- 1697
            P +     C    A G  V       AI  S+K  +  E      + R   L+D  +Y  
Sbjct: 2840 PGEDVELRCELSRA-GTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTC 2898

Query: 1698 ----QRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753
                 + +A   V  +A  FT  + +++V E   A F  +      P   V W +  + +
Sbjct: 2899 EVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCK---TEHPAATVTWRKGLLEL 2955

Query: 1754 EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ 1813
             AS +     +   + L +  +   DS TYTC    ++G+A + + L VQ +    +E  
Sbjct: 2956 RASGKHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLVQGRRVHIIEDL 3011

Query: 1814 HESALQK 1820
             +  +Q+
Sbjct: 3012 EDVDVQE 3018



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 45/197 (22%), Positives = 79/197 (40%), Gaps = 15/197 (7%)

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            +++ +A     ++  QD  ++EG+   F CR++     E  W +    ++ +  + I V 
Sbjct: 4242 QLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVE 4301

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            +   H L +  VTL D+G V+       G  + + +L V  K  VV  + +E    L   
Sbjct: 4302 QGTLHLLTLHKVTLEDAGTVSF----HVGTCSSEAQLKVTAKNTVV--RGLENVEAL--- 4352

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            EG   +   +         TW  D  P+    N E+    +G    L +   +  D+   
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDS--- 4409

Query: 562  QCTAQNVAGSTATRARL 578
             C    +AG   T A L
Sbjct: 4410 -CRVTFLAGDMVTSAFL 4425



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 5/114 (4%)

Query: 941  LRVEWLKDGRPV-EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            +R  WLKDG  + +           G  +L I  +   DAG YTC+  N  GQ T SA  
Sbjct: 4927 VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSA-C 4985

Query: 1000 TIVTKKDIIAESQHPGGLEKIQYLEDASRYSK--RTEEEVKITQKPRFLGPLKG 1051
             +V+  +  AES   G L+   +   A R  +  RT+   +++ +  FL   +G
Sbjct: 4986 VVVSGSESEAESSSGGELDD-AFRRAARRLHRLFRTKSPAEVSDEELFLSADEG 5038



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 9/129 (6%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAG 980
            EG  A F   +E  G    ++ W KDG  +   ++  T      G + L I++ +  D G
Sbjct: 6121 EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGL-EKIQYLEDASRYSKRT---EEE 1036
             Y C   N +G A  SA L I +      E  H   L   ++  E  ++  K+T   EE 
Sbjct: 6179 LYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEET 6238

Query: 1037 V-KITQKPR 1044
            +  + + PR
Sbjct: 6239 ITTVVKSPR 6247



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            ++ EG  AH    L   G     +EW      +    + + V       L + G +  D+
Sbjct: 3989 EVDEGGTAHLCCELSRAGAS---VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA 4045

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            G Y+C   +    A +SV++         +P+F T +Q++E  + G  A   C +   + 
Sbjct: 4046 GDYTCDTGHTQSMASLSVRV--------PRPKFKTRLQSLE-QETGDIARLCCQLSDAES 4096

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              + ++W   G  +    + +  S      L I   +  D+GEY C
Sbjct: 4097 GAV-VQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC 4141



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 22/82 (26%), Positives = 35/82 (42%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F     D +   G   R +C V  +      W  +  ++ D  +H I     G  +L+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957

Query: 452  ITNVTLSDSGVVTCVARNKSGE 473
            IT +  +D+G  TC   NK G+
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQ 4979



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-ILI 4469
            P+F  ++Q   V +     F+    G+P+P ++W+++   ++    + I+        LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I  V   D  V+  +AEN  G +   A L V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 6/132 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++     V   G +    C +  +  PT ++ W  + +P+ +G R++   D     L I
Sbjct: 12   FLTRPKAFVVSVGKDATLSCQIVGN--PTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQH----PQGKAGLEAVEQAE 2891
                  DSG Y C+A N+ G A  +  L+   +        H    P      E  E   
Sbjct: 70   LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATF 129

Query: 2892 EARLAKGRRPSV 2903
              R+    RP+V
Sbjct: 130  RCRVGGSPRPAV 141



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 42/204 (20%), Positives = 80/204 (39%), Gaps = 11/204 (5%)

Query: 364  QDQRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            Q    +Y  +   +     ++++E K +  +   V ++     G  T   C V  +   E
Sbjct: 1414 QADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVA-QAQTE 1472

Query: 423  VTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            V W+ + +++   ++ K+ +   G    L++     + +G  +C A    G       L+
Sbjct: 1473 VMWYKDGKKL--SFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFHLH 1526

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V E + V A K       +    G    L+       T  +TW KDG  +  + ++R+  
Sbjct: 1527 VAEPKAVFA-KEQPASREVQAEAGTSATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEA 1584

Query: 542  DGGASTLDIPRAKASDAAWYQCTA 565
             G    L +  A  +DA  Y C A
Sbjct: 1585 VGCTRRLVVQEAGQADAGEYSCKA 1608



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            A +F R L  +    G  V L C L P       V W C    ++ G RF+   E    +
Sbjct: 1808 AAKFCRLLEPVCGELGGTVTLACELSPA---CAEVVWRCGNTQLRVGKRFQMVAEGPVRS 1864

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            L +L +  ED+G Y C++ +    A  + ++  + K
Sbjct: 1865 LTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVK 1900



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 13/122 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P KF   +++    E       C +  K  P   +EW++  + L  G R+    D     
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELS-KMAP---VEWWKGHETLRDGDRHSLRQDGARCE 3680

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  + AED+GEY+C      G++ T A ++ + +P   ++     G++  EA     A
Sbjct: 3681 LQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE-----GLRNEEATEGDTA 3731

Query: 3949 TI 3950
            T+
Sbjct: 3732 TL 3733



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 11/119 (9%)

Query: 1300 QVREDITV-MQAPQ--FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            Q R   T+ ++APQ  F   L +++  EG+   L+C L    + T  V W   G  ++  
Sbjct: 3876 QERTSATLTVRAPQPVFREPLQSLQAEEGSTATLQCELS---EPTATVVWSKGGLQLQAN 3932

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL-ESQH 1414
             R  P  +     L L  +  ED+G YTC      G   TS  L V A     L E QH
Sbjct: 3933 GRREPRLQGCTAELVLQDLQREDTGEYTCTC----GSQATSATLTVTAAPVRFLRELQH 3987



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTL 4571
            P F+ T  +     G  +RL+  V     +   WLK+G ++  D R+  +++  DGT +L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT-DGRHHHIDQLGDGTCSL 4956

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            LI      D+G Y C   N  G+    A  VVS
Sbjct: 4957 LITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGF 3752
            PP F  E+ D      G  V   CRV   G P   I W+ +G+          + D  G 
Sbjct: 6013 PPDFEEELAD-CTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGS 6069

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             AL +D +   D+G+Y C A +  G+ +T  KI
Sbjct: 6070 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKI 6102



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R   A  M  L +      D+G Y+C A    G   +S  L+ V
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRLSFHLD-V 1343

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             + K    +     + ++  + G  A   C V        ++ WY +G+ +  S++++  
Sbjct: 1344 SEPKAVFAKEQLAHRKVQA-EAGAIATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRME 1399

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            +      L +      D+GEY C A
Sbjct: 1400 AVGCTRRLVVQQACQADTGEYSCEA 1424



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165
            +AR   V   L DA   EEG WA F C ++ H    V W LNG  + N S +++++ G  
Sbjct: 2554 EAREVTVTGPLQDAEATEEG-WASFSCELS-HEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611

Query: 4166 HFDIPKTRQ 4174
            H  + K+ Q
Sbjct: 2612 HTLVLKSIQ 2620



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP FV+   A    EGE A+F C + G P P++ W  +G  +  G++++
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
           ES +++       L    PP  A +   ++L E  +AQ   +LS +    VTW K+G+ L
Sbjct: 690 ESSIRMEVRAAPGLTANKPPAAAAREVLARLHE--EAQLLAELS-DQAAAVTWLKDGRTL 746

Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               K+E+  +     L VR+  + D+G Y
Sbjct: 747 SPGPKYEVQASAGRRVLLVRDVARDDAGLY 776



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 11/175 (6%)

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            F K  + + V E      +  +T RP+PE+ W  N   +    N +I   E   H L++ 
Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHA-EGARHRLVLH 2047

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV  +D G   C    ++ +   Q +L V E  QV   + V     +  RE     +  +
Sbjct: 2048 NVGFADRGFFGC----ETPDDKTQAKLTV-EMRQV---RLVRGLQAVEAREQGTATMEVQ 2099

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
                     +W +DG+     P   +   G   TL +   +  D+      A+ V
Sbjct: 2100 LSHADVDG-SWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGV 2153



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371
            +F  AL ++E +EG    L C L  V      V+W      ++ G ++    E   + L 
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELV 3242

Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            + ++ P+DSG Y+C      G+  TS  L V A
Sbjct: 3243 VRNLRPQDSGRYSC----SFGDQTTSATLTVTA 3271



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
            +P F  PLQ L + +EG  A  + +L   S+PT  V W K G  + A+ R          
Sbjct: 3889 QPVFREPLQSL-QAEEGSTATLQCEL---SEPTATVVWSKGGLQLQANGRREPRLQGCTA 3944

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             L +  L+ ED G YT    ++   A  T +
Sbjct: 3945 ELVLQDLQREDTGEYTCTCGSQATSATLTVT 3975



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            Q  +A+ K   +++    Q+R  + + V + P F  +L   T    G++    CR+   P
Sbjct: 5985 QARTAIIKSSWVKEICGIQQR--LALPVWRPPDFEEELADCTA-ELGETVKLACRVTGTP 6041

Query: 1873 DPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             P   + WY +GK +Q   H     +  G  AL + ++ G DSG+Y C A +  G   + 
Sbjct: 6042 KPV--ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTL 6099

Query: 1932 IRLNVQ 1937
             ++ VQ
Sbjct: 6100 GKILVQ 6105



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 77/397 (19%), Positives = 149/397 (37%), Gaps = 37/397 (9%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            E  +K +      + ++     E  +A FE +     +    W  ++ P+  S + ++  
Sbjct: 4331 EAQLKVTAKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVF 4390

Query: 4462 FST--KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            F    + +L+++ +  +DS     +A    G    SA L V   R +    I+ P     
Sbjct: 4391 FENGLRHLLLLKNLRPQDSCRVTFLA----GDMVTSAFLTVRGWRLE----ILEP----- 4437

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGT-YTLLILEAY 4577
             +N  V +G        ++   P+ +  W  NG  VQPD  +  +  DG+ + LL+  A 
Sbjct: 4438 LKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQ 4497

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
            P  +G+      ++   AR     V+ LP   D P+     A +   +        +++G
Sbjct: 4498 PHHAGEVTFACRDAVASARL---TVLGLP---DPPEDAEVVARSSHTVTLSWAAP-MSDG 4550

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIK-PSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
                   ++  K   T QW    +L+  P          + Y  R++   P   G+    
Sbjct: 4551 GGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGE---- 4606

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
              +    V +A   K   P      P+    R +    G+    + ++ ++    I W +
Sbjct: 4607 PVHLPQTVRLAEPPKPVPPQ-----PSAPESRQVAA--GEDVSLELEVVAEAGEVI-WHK 4658

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                I     F+++ +G   +L+I     ED G + C
Sbjct: 4659 GMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 11/151 (7%)

Query: 4585 ECVAINSA-GEA-RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL----KDKIVAEGQ 4638
            ECV    A GE  R     V  + A +    PQT     PP+ + P     + + VA G+
Sbjct: 4580 ECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGE 4639

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC-VA 4697
             +    ++V +    + W+KG + I+P   F++     +  L I     ED+G+Y C +A
Sbjct: 4640 DVSLELEVVAEAGEVI-WHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLA 4698

Query: 4698 YNS--AGRVTVAAKLKVTQPDQADNLPALTP 4726
              S      T    L     D+A   P+L P
Sbjct: 4699 QGSICPAAATFQVALSPASVDEAPQ-PSLPP 4728



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/151 (23%), Positives = 51/151 (33%), Gaps = 4/151 (2%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            V PE +     +   PVF++      V++G    F C VTG P P V W  +G  +    
Sbjct: 5111 VPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD 5170

Query: 4156 RYKLTYD--GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNA 4213
             Y +  D  G +   I      D G    +             L+V     DY       
Sbjct: 5171 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADAT 5230

Query: 4214 PRPWYDETTQY--QRTETELEKTFEERQVLQ 4242
                Y     Y   R +   E T +E Q+ Q
Sbjct: 5231 ESSSYFSAQGYLSSREQEGTESTTDEGQLPQ 5261



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            PRF+T+ ++    V  + T   CQ+  VG+P  +V W  + +P+    RF    D     
Sbjct: 10   PRFLTRPKAFVVSVGKDAT-LSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 4033 MNFGWVYPEDSGEYLCRATNLYG 4055
            +    +   DSG+Y+CRA N  G
Sbjct: 67   LTILDLALGDSGQYVCRARNAIG 89



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R         L +      D+G YSC+A    G   +S  L   
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVA 1620

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            +           H + ++  + G SA   C V        ++ WY +G+ +  S++++  
Sbjct: 1621 EPKVVFAKEQPAH-REVQA-EAGASATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRVE 1675

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            +      L +      ++GEY C A
Sbjct: 1676 AVGCTRRLVVQQAGQAEAGEYSCEA 1700



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 12/111 (10%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            ++W+ +   +  S + +      M  L IL     D+G Y C+A +     E++V     
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTV----- 2553

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++   T  +Q+ E  ++G  A F C    +   D ++EW  NG P+
Sbjct: 2554 ---EAREVTVTGPLQDAEATEEGW-ASFSC---ELSHEDEEVEWSLNGMPL 2597



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 7/97 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P   I PL+      G  +     +   G P   + WLK+ ++I  S ++  +       
Sbjct: 2826 PAAIIKPLEDQWVAPGEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAM 2882

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            L +   +++D+GEYTC   +    +++ A LHV  +A
Sbjct: 2883 LVIRGASLKDAGEYTCEVEA----SKSTASLHVEEKA 2915



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 43/172 (25%), Positives = 64/172 (37%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +T+    R           L+I G    D+G YSC      GQ   S  L   
Sbjct: 3743 VEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVC----GQERTSATLTV- 3797

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
               +    RF   ++N E  ++G +A  +C +         +EW    + +R   R    
Sbjct: 3798 ---RALPARFIEDVKNQEA-REGATAVLQCEL----SKAAPVEWRKGSETLRGGDRYSLR 3849

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             D     L I      D+GEY C      G++ T AT+       V+ E LQ
Sbjct: 3850 QDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVRAPQPVFREPLQ 3897



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 17/143 (11%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S ++ V  P+++    + E      + EG+ A F+C++        R      G  LQ+ 
Sbjct: 4240 SAQLTVRAPEVT----ILEPLQDVQLSEGQDASFQCRLSRASGQEARWAL--GGVPLQAN 4293

Query: 2289 ARFHITFDFGYVSLDIQHCVP-EDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
                IT + G + L   H V  EDAG  S      +G C+S   + VTAK +++      
Sbjct: 4294 EMNDITVEQGTLHLLTLHKVTLEDAGTVSFH----VGTCSSEAQLKVTAKNTVV------ 4343

Query: 2348 EGLEKIRELESAEPFKRPEIPEP 2370
             GLE +  LE  E     ++ +P
Sbjct: 4344 RGLENVEALEGGEALFECQLSQP 4366



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+S L+ +V +EG    F+C V PS    + + WF +   L    ++  +   +  SL I
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPS---DVAVVWFRDGALLQPSEKFAISQSGASHSLTI 1957

Query: 2836 THTYEEDSGIYTCKATNSKGSA 2857
            +    ED+G  T +A  +  SA
Sbjct: 1958 SDLVLEDAGQITVEAEGASSSA 1979



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 57/275 (20%), Positives = 105/275 (38%), Gaps = 35/275 (12%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V     + V W ++G  +QP  +  I +   +++L I +   +D+G+   + + + G + 
Sbjct: 1921 VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ---ITVEAEGASS 1977

Query: 4597 CDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
              A  V   P   K K +PQT                 V E  ++    ++  +P P ++
Sbjct: 1978 SAALRVREAPVLFKKKLEPQT-----------------VEERSSVTLEVELT-RPWPELR 2019

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            W +    + P K  ++      + L +      D G + C   +   +    AKL V   
Sbjct: 2020 WTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ----AKLTV--- 2072

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
             +   +  +  L+ +   E   A  + Q+ S       W R+G    + P   +   G  
Sbjct: 2073 -EMRQVRLVRGLQAVEAREQGTATMEVQL-SHADVDGSWTRDGLRFQQGPTCHLAVRGPM 2130

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              L +     ED+G    +A      V TSA+LVV
Sbjct: 2131 HTLTLSGLRPEDSGLMVFKAE----GVHTSARLVV 2161



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 5/70 (7%)

Query: 804  VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            V+WYKD  P++ S +           L I+ L   DAG Y  +A    G A S+  + V 
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 864  ARS-TVTADL 872
            AR  TVT  L
Sbjct: 2555 AREVTVTGPL 2564



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 32/126 (25%), Positives = 56/126 (44%), Gaps = 11/126 (8%)

Query: 2617 EQIQLKEAAMNKVPEMFVDTG----VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            + IQ  +A + +   + V T     V+  P+    LK+ D L   +   L  Q E  +DP
Sbjct: 2617 KSIQRADAGIVRASSLKVSTSARLEVRVKPV--VFLKALDDLSAEERGTLALQCEV-SDP 2673

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
               + W K+GV L    +       G   L ++ +  +D+G+YTC     +G   + A +
Sbjct: 2674 EAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARV 2729

Query: 2733 KIEDRH 2738
            ++ D H
Sbjct: 2730 RVHDLH 2735



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 11/126 (8%)

Query: 1815 ESALQKIQQLEDSSRY-----QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRI 1868
            E  LQ +Q+ ED+  Y      +     + V  AP RF+ +L    ++ EG +AH  C +
Sbjct: 3945 ELVLQDLQR-EDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQ-EVDEGGTAHLCCEL 4002

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
                     VEW      L    +Y+   D   A L +  V  ED+G+YTC   +    A
Sbjct: 4003 SR---AGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMA 4059

Query: 1929 VSSIRL 1934
              S+R+
Sbjct: 4060 SLSVRV 4065



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 35/166 (21%), Positives = 63/166 (37%), Gaps = 10/166 (6%)

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            +Y   T  ++T   + ++E  +    V+   D +VT  +   F C V+      V W + 
Sbjct: 4138 EYACVTGGQKTAASLRVTEPEVT--IVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQ 4195

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
               ++ +   ++ V +   H L +  VT  D+G V+       G  A   +L V   E  
Sbjct: 4196 GLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF----HLGNHASSAQLTVRAPEVT 4251

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534
            +    +E    + + EG+      R          W   GVP+  N
Sbjct: 4252 I----LEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQAN 4293



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 4/106 (3%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG-HRYRT 1895
            E+   + P F +   G T+   G +   EC +    D  +R  W  +G  L  G H +  
Sbjct: 4891 EMKQQEGPMF-SHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHID 4947

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
                G  +L I  +   D+G YTC+  N  GQ   S  + V   ES
Sbjct: 4948 QLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSES 4993



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   ++  +   + G   +   +++G P+P ++W+K+G+ +     H +I   + +   
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 325  VRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESP 358
            + ++    DSG Y   A +  G   T G + V+ P
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 16/201 (7%)

Query: 2538 PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXX 2597
            P++   W  +GVEL+ G            +L I      D G+Y+C A +          
Sbjct: 2192 PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHD---AQSSASV 2248

Query: 2598 XXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEG 2657
                    +I + +  E   +IQ    A N   E      V++ P+ T      DK+   
Sbjct: 2249 KVQGRTYTLIYRRVLAEDAGEIQF--VAEN--AESRAQLRVKELPV-TLVRPLRDKIAME 2303

Query: 2658 QH-VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            +H   LE QV   +  + ++ WFK    L  G + +   D     L I+ +  +D   YT
Sbjct: 2304 KHRGVLECQV---SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYT 2360

Query: 2717 CKATNLLGEAVSTASIKIEDR 2737
            C A    G+  ++A   +E++
Sbjct: 2361 CDA----GDVKTSAQFFVEEQ 2377



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 8/96 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P RF   +KD ++V EGG     C +  V  P   + W +       G +     +   +
Sbjct: 3184 PVRFQEALKD-LEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAML 3239

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
             L +  +  +D+G Y+C     +G  TT+A +T +A
Sbjct: 3240 ELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTA 3271



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 7/87 (8%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            +LK++E+ EG  A    R + +S     V+W + N  L+ G +++       + L + + 
Sbjct: 3190 ALKDLEVLEGGAATL--RCV-LSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNL 3246

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIV 1669
             P+DSG Y+C    + G+  TS    V
Sbjct: 3247 RPQDSGRYSC----SFGDQTTSATLTV 3269



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 6/109 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P K  +  RN +  EGA A  + +LS      V W+K  + L + ++H +        L+
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELS--KMAPVEWWKGHETLRDGDRHSLRQDGARCELQ 3682

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            +R     D+G Y  +     G   TS  L V +    +++  R++  T+
Sbjct: 3683 IRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLRNEEATE 3727



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 9/124 (7%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P KFI  +++    E +     C +  K  P   +EW +  + L  G R+    D     
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS-KAAP---VEWRKGHETLRDGDRHSLRQDGSRCE 3768

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  +   D+GEY C      G++ T AT++ + LP   +++ V     R  A   ++ 
Sbjct: 3769 LQIRGLAVVDAGEYSCVC----GQERTSATLTVRALPARFIED-VKNQEAREGATAVLQC 3823

Query: 3949 TIKK 3952
             + K
Sbjct: 3824 ELSK 3827



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 7/121 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L N    EGD     C +  +      +EW   ++ L  G R+    D S   L I
Sbjct: 3716 FIEGLRNEEATEGDTATLWCELSKAAP----VEWRKGHETLRDGDRHSLRQDGSRCELQI 3771

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                  D+G Y+C     + SAT   ++R    + I  D ++ + + G  AV Q E ++ 
Sbjct: 3772 RGLAVVDAGEYSCVCGQERTSATL--TVRALPARFIE-DVKNQEAREGATAVLQCELSKA 3828

Query: 2896 A 2896
            A
Sbjct: 3829 A 3829



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 10/116 (8%)

Query: 1831 QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Q R    + V   P RFI  +    +  EG +A  +C +         VEW    + L+ 
Sbjct: 3788 QERTSATLTVRALPARFIEDVKNQ-EAREGATAVLQCELSKAAP----VEWRKGSETLRG 3842

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
            G RY    D     L I  +   D+GEY+C      GQ  +S  L V++ + + R+
Sbjct: 3843 GDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVRAPQPVFRE 3894



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 38/146 (26%), Positives = 59/146 (40%), Gaps = 12/146 (8%)

Query: 1385 CQATNQLGEAVTSCA---LRVIAKKDLILESQHPSGLEKIQYLEDTSRY---KKTDIIDE 1438
            C+ +    E V  C    LRV  +  ++ E    S        ED   Y    + D    
Sbjct: 1830 CELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSA 1889

Query: 1439 SVTIK-PRFVTRPKSIENVI--EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
             +T+  PR V     +  V+  EG    F+C + P   S++ V WF++G  +    +F  
Sbjct: 1890 QLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAI 1946

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRA 1521
                   +L I DL+ ED+G  T  A
Sbjct: 1947 SQSGASHSLTISDLVLEDAGQITVEA 1972



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 76/330 (23%), Positives = 129/330 (39%), Gaps = 41/330 (12%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P  F+  +   + EE   +  +C V    DP+  + W ++G  L    +Y  ++  G   
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCEVS---DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG 2702

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L +  V  ED+G Y C      G + T+A +   ++ D  L   + + +K  E L     
Sbjct: 2703 LVVHDVSPEDAGLYTCHV----GSEETRARV---RVHD--LHVGITKRLKTMEVLEGESC 2753

Query: 3949 TIKKYTSEVYLTEDDLYDVDKK---QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNM 4005
            + +   S    ++  ++ V  K      RF    Q +  ++ +     E   +  G+   
Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVR----EAAPSDAGEVVF 2809

Query: 4006 KVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCR----ATNLYGMDETKA 4061
             V    +   L+ + R   I       +   WV P +  E  C      T ++ + + KA
Sbjct: 2810 SVRGLTSKASLIVRERPAAIIK----PLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKA 2865

Query: 4062 VIKTTGKPGIVYDSQLP------KHMKSI-EKIREMEASWQVTPEQVVEESKARCPPVFV 4114
            + K+  K  +V +  +         +K   E   E+EAS + T    VEE KA C   F 
Sbjct: 2866 IRKSQ-KYDVVCEGTMAMLVIRGASLKDAGEYTCEVEAS-KSTASLHVEE-KANC---FT 2919

Query: 4115 SLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
                 + VEE   A F C+ T HP   V W
Sbjct: 2920 EELTNLQVEEKGTAVFTCK-TEHPAATVTW 2948



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 8/110 (7%)

Query: 1974 VVEKPQ-FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V EKP  F + + +A +TEG  + L    +  + P   V W  +G+ ++   R + +++ 
Sbjct: 3091 VTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP---VCWTKDGKTLRGSARCQLSHEG 3147

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082
                L I  A  +D+G Y C+A    G A ++S V+V A+   + + L +
Sbjct: 3148 HRAQLLITGATLQDSGRYKCEA----GGACSSSIVRVHARPVRFQEALKD 3193



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            I + P +FI  +K+    E      +C +         +EW +  + L  G RY    D 
Sbjct: 3533 IRALPARFIEDVKNQEAREGATAVLQCELNSAAP----VEWRKGSETLRDGDRYSLRQDG 3588

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+GEY C      G++ T A ++ + LP
Sbjct: 3589 TKCELQIRGLAMADTGEYSCVC----GQERTSAMLTVRALP 3625



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 9/124 (7%)

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            Q R    + V   P   T+     + +EG +A   C +         VEW+   + L+ G
Sbjct: 3612 QERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDG 3667

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES-IIRDSQHE 1949
             R+    D     L I  +  ED+GEY C      G+  +S  L V++  S  I   ++E
Sbjct: 3668 DRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLRNE 3723

Query: 1950 SALE 1953
             A E
Sbjct: 3724 EATE 3727



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 9/101 (8%)

Query: 1454 ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAED 1513
            E   EG      C+L  +      VEW+K  + +  G R     D     L I  L+AED
Sbjct: 3635 EEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAED 3690

Query: 1514 SGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLE 1553
            +G Y C    + G +  S  LT R+  +  +   +NE   E
Sbjct: 3691 AGEYLC----MCGKERTSAMLTVRAMPSKFIEGLRNEEATE 3727



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++          L +     TD+G YSC A    GQ  +S +L   
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEAR---GQ-RVSFRLHIT 1068

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            +         + H  N    + G SA   C V        ++ WY +G+ +  S+++   
Sbjct: 1069 EPKMMFAKEQSVH--NEVQAEAGASAMLSCEVA---QAQTEVTWYKDGKKLSSSSKVGME 1123

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
                   L +      D+GEY C A
Sbjct: 1124 VKGCTRRLVLPQAGKADAGEYSCEA 1148



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P  F++  K+    +GG A     L     PV  W      L   +KYS+R  ++   + 
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGDKYSLR--QEGAMLE 3240

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163
            L+++ + P D G Y+C+  +Q   A  +V   P
Sbjct: 3241 LVVRNLRPQDSGRYSCSFGDQTTSATLTVTALP 3273



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 8/97 (8%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P  FI +++     E       C +  K  P   +EW +  + L  G R+    D     
Sbjct: 3361 PAHFIGRLRHQESIEGATATLRCELS-KAAP---VEWRKGRESLRDGDRHSLRQDGAVCE 3416

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L I  +   D+GEY C      GE+ T AT++ K LP
Sbjct: 3417 LQICGLAVADAGEYSCVC----GEERTSATLTVKALP 3449



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 38/172 (22%), Positives = 67/172 (38%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +T+    R           L+I G    D+G YSC    +   A ++V+   +
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPI 3626

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                    +FT  ++N E   +G +A   C +  +      +EW+   + +R   R    
Sbjct: 3627 --------KFTEGLRNEEAT-EGATAVLRCELSKM----APVEWWKGHETLRDGDRHSLR 3673

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             D     L I      D+GEY+C      G++ T A +        ++E L+
Sbjct: 3674 QDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLR 3721



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 9/108 (8%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV   P +F+  L N E  EG    L C L  +      VEW+   + ++ G R     
Sbjct: 3619 LTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQ 3674

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILE 1411
            +     L +  +  ED+G Y C      G+  TS  L V A     +E
Sbjct: 3675 DGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE 3718



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 8/94 (8%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P +FI  +K+    E      +C +  K  P   +EW +  + L  G RY    D     
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCELS-KAAP---VEWRKGSETLRGGDRYSLRQDGTRCE 3856

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            L I  +   D+GEY C      G++ T AT++ +
Sbjct: 3857 LQIHGLSVADTGEYSCVC----GQERTSATLTVR 3886



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 60/272 (22%), Positives = 105/272 (38%), Gaps = 29/272 (10%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F +  ++ +  +G  A  + +L   PT  V W++    L    +   R    T +  L
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAE--L 3946

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            +++ +   D GEYTCT  +Q   A  +V   P               ++ V E       
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLTVTAAP-------VRFLRELQHQEVDEG------ 3993

Query: 192  GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE--SD 249
            GT     E SR    V +  G    S   F     +Y+++++ +  E + +    E   D
Sbjct: 3994 GTAHLCCELSRAGASVEWRKG----SLQLF--PCAKYQMVQDGAAAELLVRGVEQEDAGD 4047

Query: 250  VQISTEIDRSLGPVS----PPKIAQKPRNSKLQEGADAQFQVQLS-GNPRPRVTWFKNGQ 304
                T   +S+  +S     PK   + ++ + + G  A+   QLS       V W K G 
Sbjct: 4048 YTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGV 4107

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L    K+E+ +      L +   +  D+G Y
Sbjct: 4108 ELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 6/108 (5%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G   T  TLT  A    P  F        + E  +AH  C L     S   VEW      
Sbjct: 3964 GSQATSATLTVTAA---PVRFLRELQHQEVDEGGTAHLCCELSRAGAS---VEWRKGSLQ 4017

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
            L   ++ + + D     L + GV Q DAG YTC   +    A++S ++
Sbjct: 4018 LFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP F       T E GE  +  CRVTG PKP + W  +G  +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAV 6054



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/56 (32%), Positives = 28/56 (50%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            VG+P+ +  W  +   +  G+RFR   D     L I  +   D+G Y+C+A N  G
Sbjct: 34   VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIG 89



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 7/122 (5%)

Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
           VGE  V     +       +  ++A+  R  + + GA A    +++   +  VTW+K+G+
Sbjct: 872 VGEDSVDFRLRVSEPKVVFAKEQLAR--RKLQAEAGASATLSCEVA-QAQTEVTWYKDGK 928

Query: 305 RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           +L +S+K  +  T     L V+   ++D+G Y+  A    G    S +L V+ P   + +
Sbjct: 929 KLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA----GGQRLSFHLDVKEPKVVFAK 984

Query: 365 DQ 366
           DQ
Sbjct: 985 DQ 986



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 58/241 (24%), Positives = 96/241 (39%), Gaps = 21/241 (8%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVS-LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            V+W +    L   +K  M   E  G    L++++ G  D GEY+C A +Q       V  
Sbjct: 1565 VTWYKDGKKLSSSSKVRM---EAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHV-A 1620

Query: 162  QPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF 221
            +P+              +R V    E  A  T      Q+ QT+   Y +G   SS+   
Sbjct: 1621 EPK-----VVFAKEQPAHREVQ--AEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKV 1672

Query: 222  KVDTF--EYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKP-RNSKL- 277
            +V+      RL+ + + +    +        Q+S  +  +      P+I+++P R   L 
Sbjct: 1673 RVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVA---ELEPQISERPCRREPLV 1729

Query: 278  -QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +E  D      L+      VTW K+G  +  S +HE  +  +  TL V   Q  DS  Y
Sbjct: 1730 VKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIY 1789

Query: 337  T 337
            +
Sbjct: 1790 S 1790



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 45/172 (26%), Positives = 72/172 (41%), Gaps = 13/172 (7%)

Query: 2245 VTELRGTTHVFEGKTAHFECQV--EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
            +T+   T  V EG++  FEC +  E   DP +   +   GK + S++RF  T       L
Sbjct: 2738 ITKRLKTMEVLEGESCSFECVLSHESASDPAM---WTVGGKTVGSSSRFQATRQGRKYIL 2794

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPF 2362
             ++   P DAGE  V ++  L   TS  S+ V  + + I +    + +    ++E     
Sbjct: 2795 VVREAAPSDAGEV-VFSVRGL---TSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL 2850

Query: 2363 KRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCR---LIPVGDPTLKVE 2411
             R   P    + R    +  Q  D + EG  A    R   L   G+ T +VE
Sbjct: 2851 SRAGTPVHWLKDRKAIRKS-QKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 7/90 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KD+ V E  AA     L  V  P   V+W      +   ++ +   +   + L +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVV 3243

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            + + P+DSG Y+C      G+  TS+TL V
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTV 3269



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + + P +FI ++++    E       C +  K  P   +EW +  + L  G RY    D 
Sbjct: 3269 VTALPAQFIGKLRNKEATEGATATLRCELS-KAAP---VEWRKGSETLRDGDRYCLRQDG 3324

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+ EY C      GE+ T A+++ + +P
Sbjct: 3325 AMCELQIRGLAMVDAAEYSCVC----GEERTSASLTIRPMP 3361



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            K  ++  E ++   P F+    D  +   G  +  +C V    D  +R  W  +G     
Sbjct: 4884 KGYKVRKEMKQQEGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVELTD 4940

Query: 3741 GSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            G   H   L D G  +L I  +   DAG YTC+ +NK+G  T +A +  S
Sbjct: 4941 GRHHHIDQLGD-GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS--NRLTTMHDFG 1766
            + P+F+    D       A   E  +    D  +R  WL++GV +     + +  + D G
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD-G 4952

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
              +L +  ++  D+G YTC+  N+ G+ VT S   V S +  + ES
Sbjct: 4953 TCSLLITGLDRADAGCYTCQVSNKFGQ-VTHSACVVVSGSESEAES 4997



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 6/125 (4%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK-NGQRLI-----NSNKHEIITTH 318
            PP++ ++    K+++G+   F V++ G P P V W +   +R +     ++  + + ++ 
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 319  NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378
               +L + +  +   G YT +A N  G  + S  L V    +   Q++  + +  T  + 
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQG 5489

Query: 379  TEERI 383
            T + I
Sbjct: 5490 TTQAI 5494



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 12/117 (10%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI- 694
            PP+ +         +G  I F  ++E  G P   + WL+  +  E    +      GY  
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVE--GRPVPTVHWLR--EEAERGVLWIGPDTPGYTV 5425

Query: 695  -------SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
                   SL +L +  Q  G YTC A +A G A   A LHV+    +E   +  E L
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEAL 5482



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/90 (25%), Positives = 40/90 (44%)

Query: 4724 LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNT 4783
            LT  +  VV  G+ A    QI     P + W ++   +     F++  +G+   L I + 
Sbjct: 13   LTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDL 72

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               D+G + CRA  A G+   +  L V ++
Sbjct: 73   ALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 49/215 (22%), Positives = 84/215 (39%), Gaps = 18/215 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P  F+  ++D +   E   V  +C +     P + + W  +G     G  +         
Sbjct: 2165 PVSFSRPLQDVVTT-EKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACR 2220

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEK--IKEL 3811
            +L I      D G Y C A +    A ++A +    +   ++  ++    +GE   + E 
Sbjct: 2221 SLTIYRCEFADQGVYVCDAHD----AQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAEN 2276

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
               R     KE P+    P    +I    +E+  GV  EC+V        ++ W++  + 
Sbjct: 2277 AESRAQLRVKELPVTLVRP-LRDKI---AMEKHRGV-LECQVSRAS---AQVRWFKGSQE 2328

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906
            L  G +Y  V D  +  L I  V+AED   Y C A
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 47/224 (20%), Positives = 82/224 (36%), Gaps = 29/224 (12%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RP  F    KD+ ++ EG  A     L      +  ++W Y    +    +        M
Sbjct: 3183 RPVRFQEALKDL-EVLEGGAATLRCVL---SSVAAPVKWCYGNNVLRPGDKYSLRQEGAM 3238

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            + L +   +  DSG YSC   ++   A ++V             +F   ++N E   +G 
Sbjct: 3239 LELVVRNLRPQDSGRYSCSFGDQTTSATLTVT--------ALPAQFIGKLRNKEAT-EGA 3289

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A   C +         +EW    + +R   R     D     L I      D+ EY C 
Sbjct: 3290 TATLRCELSKA----APVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCV 3345

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269
                 GE+ T A++         +  +    + ++R  ES++GA
Sbjct: 3346 C----GEERTSASLT--------IRPMPAHFIGRLRHQESIEGA 3377



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PKF T+++S   E  +  R  C++   E   + ++W + G  L +G +Y          L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAV-VQWLKEGVELHAGPKYEMRSQGATREL 4126

Query: 3890 DILYVYAEDSGEYIC 3904
             I  + A+D+GEY C
Sbjct: 4127 LIHQLEAKDTGEYAC 4141



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFGYVA 2036
            P F + + +     G  V L   +T    P   + WY +G+ VQ   H        G  A
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +      D+G YMC A +A G   T   + V
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 9/115 (7%)

Query: 1825 EDSSRY--QRREDVEVA--VNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRV 1878
            ED+  Y  + R+D   A      PR +  ++G + +   EG  A ++C + P    ++ V
Sbjct: 1873 EDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP---SDVAV 1929

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             W+ +G +LQ   ++  S      +L I  +  ED+G+ T +A      A   +R
Sbjct: 1930 VWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P  F+  L  ++A E G +  +     V DP   + W K+G  +  S ++  +   G   
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG 2702

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +  ++ +D+G YTC      G  ET+A + V
Sbjct: 2703 LVVHDVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 7/123 (5%)

Query: 1831 QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Q R    + +   P RFI  +    +  EG +A  +C +         VEW    + L+ 
Sbjct: 3524 QERTSATLTIRALPARFIEDVKNQ-EAREGATAVLQCELNSAAP----VEWRKGSETLRD 3578

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR-LNVQSKESIIRDSQH 1948
            G RY    D     L I  +   D+GEY+C        A+ ++R L ++  E +  +   
Sbjct: 3579 GDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEAT 3638

Query: 1949 ESA 1951
            E A
Sbjct: 3639 EGA 3641



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 1581 TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIM 1640
            T  L+N E  EG  A     L  ++     VEW+  ++ L+ G R +   +     L I 
Sbjct: 3629 TEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQIR 3684

Query: 1641 SCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE 1678
              + ED+G Y C      G+  TS +  V +  S ++E
Sbjct: 3685 GLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE 3718



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            RP F T L SLE  + GD A   C++    +    + W   G ++ AG +Y         
Sbjct: 4067 RPKFKTRLQSLEQ-ETGDIARLCCQLSDA-ESGAVVQWLKEGVELHAGPKYEMRSQGATR 4124

Query: 2168 ALDILYTYAEDSGTYMC 2184
             L I    A+D+G Y C
Sbjct: 4125 ELLIHQLEAKDTGEYAC 4141



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 49/191 (25%), Positives = 77/191 (40%), Gaps = 21/191 (10%)

Query: 1678 ESQHEGALPRL--NQLE--DTSKY------QRHSAQDEVITQAPVFTMPMKDIRVAENQA 1727
            E + +GA   L  +QLE  DT +Y      Q+ +A   V          + D  V  ++ 
Sbjct: 4116 EMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADED 4175

Query: 1728 AHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT--TMHDFGYVALNMKYVNPEDSGTYTC 1785
              F   +   G     V+W   G+P++ SN +T   + D     L +K V PED+GT + 
Sbjct: 4176 VEFSCEVSRAG--ATGVQWCLQGLPLQ-SNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF 4232

Query: 1786 RAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEV--AVNQA 1843
                 LG   +S+ L V++     LE   +  L + Q      R  R    E   A+   
Sbjct: 4233 ----HLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGV 4288

Query: 1844 PRFITQLNGPT 1854
            P    ++N  T
Sbjct: 4289 PLQANEMNDIT 4299



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 6/112 (5%)

Query: 753  YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
            +  Y+ ++ +++Q  + P F     D  E Q G     E  +   +D  +R  W KDG  
Sbjct: 4883 FKGYKVRKEMKQQ--EGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVE 4937

Query: 813  IT-ASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            +T            G  SL I  L   DAG YT +  NK G+   +A + V+
Sbjct: 4938 LTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 10/137 (7%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYDFGY 2034
            E P F     + E   G  + LE  +    D  +R  W  +G  +  G H        G 
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGT 4953

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGE-------AVTTSSVKVDAKSGLYLDTLDEQRLKK 2087
             +L I      D G Y C+ +N  G+        V+ S  + ++ SG  LD    +  ++
Sbjct: 4954 CSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARR 5013

Query: 2088 IQELEKYERPKPIEEEQ 2104
            +  L + + P  + +E+
Sbjct: 5014 LHRLFRTKSPAEVSDEE 5030



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 1/58 (1%)

Query: 928 HFEARL-EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTC 984
           H EA+L   + D    V WLKDGR +    +     + G   L ++ V   DAG Y C
Sbjct: 721 HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/145 (20%), Positives = 59/145 (40%), Gaps = 11/145 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W      +    R + V    +  L +LG +  D+G Y C + +    A+++V +  V
Sbjct: 1839 VVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRV 1898

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             K       F + +  +   ++G  A F+C V P    D+ + W+ +G  ++ S +    
Sbjct: 1899 VK-------FMSGLSTVVA-EEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAIS 1947

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
                   L I+     D+G+    A
Sbjct: 1948 QSGASHSLTISDLVLEDAGQITVEA 1972



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 9/130 (6%)

Query: 448  HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            H L ++ +   DSG++  V + +   T+   RL V E    +   F      +   E E 
Sbjct: 2131 HTLTLSGLRPEDSGLM--VFKAEGVHTS--ARLVVTE----LPVSFSRPLQDVVTTEKEK 2182

Query: 508  VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            V L    +  P   + W KDGV +     + I   G   +L I R + +D   Y C A +
Sbjct: 2183 VTLECE-LSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHD 2241

Query: 568  VAGSTATRAR 577
               S + + +
Sbjct: 2242 AQSSASVKVQ 2251



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 43/206 (20%), Positives = 79/206 (38%), Gaps = 14/206 (6%)

Query: 370  YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE-VTWFIN 428
            Y       ET  R+ + +  L     K  +  +V EG+   F+C ++     +   W + 
Sbjct: 2716 YTCHVGSEETRARVRVHD--LHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVG 2773

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
             + +      +    +   + L++     SD+G V    R  + + +    L V E+   
Sbjct: 2774 GKTVGSSSRFQA-TRQGRKYILVVREAAPSDAGEVVFSVRGLTSKAS----LIVRERPAA 2828

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            +     +++    V  GE V L        TP + W KD   I  + +  +  +G  + L
Sbjct: 2829 IIKPLEDQW----VAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAML 2883

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTAT 574
             I  A   DA  Y C  +  + STA+
Sbjct: 2884 VIRGASLKDAGEYTCEVE-ASKSTAS 2908



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 5/92 (5%)

Query: 2108 RPV-FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            RPV F  AL  LE L EG  A   C +  +  P   + W +    +R G +Y    +   
Sbjct: 3183 RPVRFQEALKDLEVL-EGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAM 3238

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            + L +     +DSG Y C   ++   A  T T
Sbjct: 3239 LELVVRNLRPQDSGRYSCSFGDQTTSATLTVT 3270



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 6/109 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P +  +  +N + +EGA A  Q +L  N    V W K  + L + +++ +        L+
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQ 3594

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            +R    +D+G Y+ +     G   TS  L V +    + +  R++  T+
Sbjct: 3595 IRGLAMADTGEYSCVC----GQERTSAMLTVRALPIKFTEGLRNEEATE 3639



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 11/102 (10%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG--- 1911
            +LSEGQ A ++CR+        R  W   G  LQ+      + + G   L +LT++    
Sbjct: 4260 QLSEGQDASFQCRLSRASGQEAR--WALGGVPLQANEMNDITVEQG--TLHLLTLHKVTL 4315

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            ED+G  +     ++G   S  +L V +K +++R  ++  ALE
Sbjct: 4316 EDAGTVSF----HVGTCSSEAQLKVTAKNTVVRGLENVEALE 4353



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/105 (24%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            VPP  +   ++  V +G+ V L+ +V      +V W K  +++QP  R +++ + G   +
Sbjct: 4623 VPPQPS-APESRQVAAGEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQ-GRQQM 4679

Query: 4572 LILEAY-PQDSGKYEC-VAINSAGEARCDAECVVSLPATKDKPKP 4614
            L+++ +  +D G+Y C +A  S   A    +  +S  +  + P+P
Sbjct: 4680 LVIKGFTAEDQGEYHCGLAQGSICPAAATFQVALSPASVDEAPQP 4724



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG-HRYRTVYDMGFVS 3888
            P F         +  + +R EC V  K D  +R  W ++G  L  G H +      G  S
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCS 4955

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L I  +   D+G Y C+  N FG+
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQ 4979



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/86 (25%), Positives = 43/86 (50%), Gaps = 1/86 (1%)

Query: 4727 LRDIVVYEG-QPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
            LRD+ V  G + A+F+ ++     P + W ++G  +  +   +M  +     L I +   
Sbjct: 5266 LRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTR 5325

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            ED+G +    + A G   +SA+L+V+
Sbjct: 5326 EDSGQYAAYISNAMGAAYSSARLLVR 5351



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 10/151 (6%)

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPP--KFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            G+  E   E       D    +  VS P   KF++ + +   EE     F+C V P +  
Sbjct: 1869 GLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSD-- 1926

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             + + W+R+G LL    ++         SL I  +  ED+G+    A        + A +
Sbjct: 1927 -VAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAAL 1981

Query: 3920 SCKKLPDIILQNQVPRGM-KRSEALTQMEAT 3949
              ++ P +  +   P+ + +RS    ++E T
Sbjct: 1982 RVREAPVLFKKKLEPQTVEERSSVTLEVELT 2012



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 15/119 (12%)

Query: 751  EDYSKYQHQESIEEQTSQR-----PQFIRPLQDLGEL--QEGRNAHFEAQLTPVSDPTMR 803
            ED  +Y   ES ++ TS +     P+ ++ +  L  +  +EG  A F+  ++P SD  + 
Sbjct: 1873 EDAGEYVC-ESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP-SD--VA 1928

Query: 804  VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            V W++DG  +  S +     +    SL I  L  EDAG  TV A      A S+A++RV
Sbjct: 1929 VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAALRV 1983



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
            V +  P+  T  + +E K G+             A   V+WY ++ PL    +F  +   
Sbjct: 2463 VVSDIPVVLT--RPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEG 2520

Query: 1633 GFVALDIMSCLPEDSGTYTCRAINA 1657
                L I+  +P D+G Y C+A +A
Sbjct: 2521 QMAELRILRLMPADAGVYRCQAGSA 2545



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 772  FIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLN 831
            F++ L DL   + G  A  + +   VSDP   V W KDG  +  S +   +   G   L 
Sbjct: 2649 FLKALDDLSAEERGTLA-LQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV 2704

Query: 832  IMHLRAEDAGSYT 844
            +  +  EDAG YT
Sbjct: 2705 VHDVSPEDAGLYT 2717



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 8/119 (6%)

Query: 2883 GLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPD 2942
            GL  V+ AE + +    R S   T  P P   I      + +EG    L  ++  K  P 
Sbjct: 3333 GLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELS-KAAP- 3390

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
              +EW    + L  G R  L  D     L +  +   D+G Y+C      GE  TS+T+
Sbjct: 3391 --VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVC----GEERTSATL 3443



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 9/101 (8%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV   P +F+  L N E VEG    L C L  V      VEW    + ++ G R+    
Sbjct: 3443 LTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAP----VEWRKGPENLRDGDRYILRQ 3498

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            E     L +  +   D+G Y C      G+  TS  L + A
Sbjct: 3499 EGTRCELQICGLAMADAGEYLCVC----GQERTSATLTIRA 3535



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 2373 RQRPV-FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431
            R  P+ FT+ L+N +   EG TA   C L  +      VEW++  + + D  R +   D 
Sbjct: 3622 RALPIKFTEGLRN-EEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDG 3676

Query: 2432 GYVSMTISHVRDEDEGVYMC 2451
                + I  +  ED G Y+C
Sbjct: 3677 ARCELQIRGLVAEDAGEYLC 3696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
            +F + ++N E TEG    L   L+ +      VEW+     ++ G R     D     L 
Sbjct: 3627 KFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQ 3682

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL 2080
            I    AED G Y+C      G+  T++ + V A    +++ L
Sbjct: 3683 IRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGL 3720



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 90/376 (23%), Positives = 143/376 (38%), Gaps = 34/376 (9%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV  AP +F R L + E  EG   HL C L   G     VEW      +    +++   
Sbjct: 3972 LTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAG---ASVEWRKGSLQLFPCAKYQMVQ 4028

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK-DLILES--QHPSGLEK 1420
            +     L +  V  ED+G YTC   +   +++ S ++RV   K    L+S  Q    + +
Sbjct: 4029 DGAAAELLVRGVEQEDAGDYTCDTGHT--QSMASLSVRVPRPKFKTRLQSLEQETGDIAR 4086

Query: 1421 I-QYLEDTSRYKKTDIIDESVTIK--PRFVTRPKSI--ENVIEGQHVHFECKLEPVTDSN 1475
            +   L D         + E V +   P++  R +    E +I         +   VT   
Sbjct: 4087 LCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQ 4146

Query: 1476 LKVEWFKNGQP-VTIGHRFRPIHDFGYVALDIIDLIAEDS-----GIYTC-RAVNLVGTD 1528
                  +  +P VTI    R + D    A + ++   E S     G+  C + + L   +
Sbjct: 4147 KTAASLRVTEPEVTI---VRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNE 4203

Query: 1529 --EVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKN 1586
              EV+ R     T  +   T  +AG     +    S    T    EVT   P     L++
Sbjct: 4204 VTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEP-----LQD 4258

Query: 1587 VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV-ALDIMSCLPE 1645
            V++ EGQ A F+ RL   S    +  W     PL++      T   G +  L +     E
Sbjct: 4259 VQLSEGQDASFQCRLSRASGQ--EARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLE 4316

Query: 1646 DSGTYTCRAINALGEA 1661
            D+GT +        EA
Sbjct: 4317 DAGTVSFHVGTCSSEA 4332



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 13/134 (9%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            +++   VF + L++   ++EG+++ L C       P   V W  +G+++   +R +  ++
Sbjct: 3091 VTEKPSVFSRELTDAT-ITEGEDLTLVCETSTCDIP---VCWTKDGKTLRGSARCQLSHE 3146

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL 1291
                 L I  AT  D+G Y   A    G A +S+IVRV  R       + ++A++ +++L
Sbjct: 3147 GHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRVHAR-----PVRFQEALKDLEVL 3197

Query: 1292 EDAARRTKQVREDI 1305
            E  A   + V   +
Sbjct: 3198 EGGAATLRCVLSSV 3211



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 8/126 (6%)

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRR-----EDVEVAVNQAPRFITQLNGP 1853
            TL   ++  L  E      L     L+DS RY+           V V+  P    +    
Sbjct: 3134 TLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
             ++ EG +A   C +     P   V+W +   VL+ G +Y    +     L +  +  +D
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQD 3250

Query: 1914 SGEYTC 1919
            SG Y+C
Sbjct: 3251 SGRYSC 3256



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W KDG+ + +SS++          L ++ V   DAG Y+C A    G    S  L I 
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSFQLHIT 1252

Query: 1003 TKKDIIAESQ 1012
              K + A+ Q
Sbjct: 1253 EPKAVFAKEQ 1262



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 2011 VEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            V+WY +  P+    +FK + +     L IL     D G Y C+A    G A +++ V V+
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 2071 AK 2072
            A+
Sbjct: 2555 AR 2556



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/140 (24%), Positives = 60/140 (42%), Gaps = 9/140 (6%)

Query: 2197 CTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256
            C L   GHR  +L T          + EA G  +   +      P RF   L+    V E
Sbjct: 3141 CQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSS-SIVRVHARPVRFQEALKDL-EVLE 3198

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            G  A   C +  V  P   +++ +    L+   ++ +  +   + L +++  P+D+G YS
Sbjct: 3199 GGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255

Query: 2317 VKAINALGHCTSAISMTVTA 2336
                 + G  T++ ++TVTA
Sbjct: 3256 C----SFGDQTTSATLTVTA 3271



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 7/97 (7%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P +F   +K   V E       C +     P   ++W     +L  G +Y    +   + 
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLE 3240

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L +  +  +DSG Y C     FG+  T AT++   LP
Sbjct: 3241 LVVRNLRPQDSGRYSC----SFGDQTTSATLTVTALP 3273



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 38/172 (22%), Positives = 68/172 (39%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +++    R        +  L+I G    D+G YSC    +   A ++V     
Sbjct: 3391 VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTV----- 3445

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
               K    +FT  ++N E + +G +A   C +  V      +EW    + +R   R    
Sbjct: 3446 ---KALPAKFTEGLRNEEAV-EGATAMLWCELSKV----APVEWRKGPENLRDGDRYILR 3497

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             +     L I      D+GEY+C      G++ T AT+        ++E ++
Sbjct: 3498 QEGTRCELQICGLAMADAGEYLCVC----GQERTSATLTIRALPARFIEDVK 3545



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 6/105 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P K  +  RN +  EG  A    +LS    P V W K  + L + ++H +    +   L+
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS-KAAP-VEWRKGHETLRDGDRHSLRQDGSRCELQ 3770

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
            +R     D+G Y+ +     G   TS  L V +    +++D ++Q
Sbjct: 3771 IRGLAVVDAGEYSCVC----GQERTSATLTVRALPARFIEDVKNQ 3811



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 6/96 (6%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG +A  +C +    +P   V W   G  LQ+  R         A L +  +  ED+GEY
Sbjct: 3903 EGSTATLQCELS---EPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            TC   +   QA S+      +    +R+ QH+   E
Sbjct: 3960 TCTCGS---QATSATLTVTAAPVRFLRELQHQEVDE 3992



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 8/119 (6%)

Query: 2087 KIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWF 2146
            KIQ   K  + +   ++Q G  P+F       E  + GD    EC V    D  +   W 
Sbjct: 4878 KIQAAFKGYKVRKEMKQQEG--PMFSHTFGDTE-AQVGDALRLECVVASKAD--VRARWL 4932

Query: 2147 HNGQKIRAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKATNKLGEAVNTCTLKVAG 2203
             +G ++  G R+      G     +L T  +  D+G Y C+ +NK G+  ++  + V+G
Sbjct: 4933 KDGVELTDG-RHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSG 4990



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P   PP F  EL   T    G+T    C+V     P   I +Y +GKA+Q      +  D
Sbjct: 6009 PVWRPPDFEEELADCTAEL-GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIED 6065

Query: 2297 -FGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              G  +L +      D+G+Y   A +A G+C++
Sbjct: 6066 PDGSCALILDSLTGVDSGQYMCFAASAAGNCST 6098



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 3/113 (2%)

Query: 1035 EEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT 1094
            ++ + +  PRFL   K     V G+ A    ++    + T  V W  + + + +  R + 
Sbjct: 2    DQPQFSGAPRFLTRPKAFVVSV-GKDATLSCQIV--GNPTPQVSWEKDQQPVAAGARFRL 58

Query: 1095 YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIH 1147
              D     L I  +   DSG Y   ARNA GEA  +  + V+  ++    + H
Sbjct: 59   AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C +     P   V WY +GK L S  + R         L +  V   D+GEY+
Sbjct: 1181 GTTAMLSCEVA---QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            C+A    GQ V S +L++   +++    Q
Sbjct: 1238 CEA---GGQRV-SFQLHITEPKAVFAKEQ 1262



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 12/145 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  I  S R  T        L + G +  DS  YSCR   + GQ +  V++E V
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAE-GQ-DFPVQVEEV 1807

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                    +F   ++ + G + G +    C + P      ++ W      +R   R + V
Sbjct: 1808 ------AAKFCRLLEPVCG-ELGGTVTLACELSPA---CAEVVWRCGNTQLRVGKRFQMV 1857

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            ++     L +   +  D+GEYVC +
Sbjct: 1858 AEGPVRSLTVLGLRAEDAGEYVCES 1882



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 1024 EDASRY---SKRTEEEVKITQK-PRFLGPLKGTNKIV--EGQSAHFEARVEPQSDLTMTV 1077
            EDA  Y   S+      ++T   PR +  + G + +V  EG  A F+  V P SD+   V
Sbjct: 1873 EDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP-SDVA--V 1929

Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL 1129
             W+ +G  +  + +          +L I+ +  ED+G  TV A  A+  A L
Sbjct: 1930 VWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAAL 1981



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 4/62 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            ++W+K+   L+   + K + +  +  L I  L   D+G+Y C+A    G A S+  + +E
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 2736 DR 2737
             R
Sbjct: 2555 AR 2556



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF+  L+++  +E   +  +C V    DP   + W  +   L    +Y   H      L 
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEVS---DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV 2704

Query: 2835 ITHTYEEDSGIYTC 2848
            +     ED+G+YTC
Sbjct: 2705 VHDVSPEDAGLYTC 2718



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/49 (34%), Positives = 23/49 (46%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583
            V DP     W  +GV+L    ++   H  G   L ++ V   DAGLY C
Sbjct: 2670 VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC 2718



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 8/114 (7%)

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
            K T+    + KA  FT  L+N++ + E   A F  +   T+ P   V W      L+A  
Sbjct: 2904 KSTASLHVEEKANCFTEELTNLQ-VEEKGTAVFTCK---TEHPAATVTWRKGLLELRASG 2959

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            + +   +   + L IS     DS  Y C    + G+A + A + VQG+R  I+E
Sbjct: 2960 KHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLVQGRRVHIIE 3009



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 13/119 (10%)

Query: 1439 SVTIKP---RFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            S+TI+P    F+ R +  E+ IEG      C+L         VEW K  + +  G R   
Sbjct: 3354 SLTIRPMPAHFIGRLRHQES-IEGATATLRCELSKAAP----VEWRKGRESLRDGDRHSL 3408

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLE 1553
              D     L I  L   D+G Y+C    + G +  S  LT ++         +NE  +E
Sbjct: 3409 RQDGAVCELQICGLAVADAGEYSC----VCGEERTSATLTVKALPAKFTEGLRNEEAVE 3463



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + + P KF   +++    E       C +  K  P   +EW +  + L  G RY    + 
Sbjct: 3445 VKALPAKFTEGLRNEEAVEGATAMLWCELS-KVAP---VEWRKGPENLRDGDRYILRQEG 3500

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+GEY+C      G++ T AT++ + LP
Sbjct: 3501 TRCELQICGLAMADAGEYLCVC----GQERTSATLTIRALP 3537



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/90 (24%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P+F   L+S  +  EG    L+ ++   ++P   + W K G+ L    R +         
Sbjct: 3890 PVFREPLQSL-QAEEGSTATLQCEL---SEPTATVVWSKGGLQLQANGRREPRLQGCTAE 3945

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            L +  L+ +D+G YTC   +    A  T +
Sbjct: 3946 LVLQDLQREDTGEYTCTCGSQATSATLTVT 3975



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTC 4793
            G   + +  + SK     +WL++G  + +     +   G+    LLI      D G +TC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971

Query: 4794 RATTAAGQVETSAKLVV 4810
            + +   GQV  SA +VV
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 5/77 (6%)

Query: 3576 HFECRLIP-VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
            H E +L+  ++D +  V W  +G+ L  G + +     G  +L +  V + DAGLY C  
Sbjct: 721  HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC-- 778

Query: 3635 TNRHGEATVSCKLQVKG 3651
             +R G   ++ +L V+G
Sbjct: 779  VSRGGR--IAYQLSVQG 793



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 13/45 (28%), Positives = 21/45 (46%)

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
           +TW KDG  + P P+  +    G   L +      DA  Y+C ++
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSR 781



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 16/51 (31%), Positives = 26/51 (50%)

Query: 797  VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
            V+ P   V WYKDG+ +++SS++          L +  +   DAG Y+  A
Sbjct: 1190 VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 4/77 (5%)

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            +  +   V W KDG+ + +SS++          L ++     DAG YTC A    G    
Sbjct: 1282 VAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRL 1337

Query: 996  SANLTIVTKKDIIAESQ 1012
            S +L +   K + A+ Q
Sbjct: 1338 SFHLDVSEPKAVFAKEQ 1354



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 3/76 (3%)

Query: 1992 GHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYM 2051
            G  V L   L+P       V W C    ++ G RF+   +    +L +L   AED G Y+
Sbjct: 1823 GGTVTLACELSPA---CAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYV 1879

Query: 2052 CKATNAVGEAVTTSSV 2067
            C++ +    A  T SV
Sbjct: 1880 CESRDDHTSAQLTVSV 1895



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/94 (26%), Positives = 36/94 (38%), Gaps = 7/94 (7%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            KP       D +S +E G    +     + D    V W KDG  +  S +       G  
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTR 2701

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L +  V+  DAG YTC     +G   T A + +
Sbjct: 2702 GLVVHDVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 7/87 (8%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            GE+      L+    P   V W  + K+++   ++   C+    +L I     +D+GEY 
Sbjct: 2841 GEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897

Query: 3495 CRAYNNYGEAVTTASMKVQGKRNIILE 3521
            C        + +TAS+ V+ K N   E
Sbjct: 2898 CEV----EASKSTASLHVEEKANCFTE 2920



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 42/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F +  +D +V EG      C ++    P V W   +  +R    +  L  E     L++
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYS-LRQEGAMLELVV 3243

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             N+   DSG  +C      G+      L V      +  +F+ +       EG    L  
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVT----ALPAQFIGKLRNKEATEGATATLRC 3295

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
              +    P + W+K    +       +  DG    L I      DAA Y C    V G  
Sbjct: 3296 E-LSKAAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC----VCGEE 3349

Query: 573  ATRARL 578
             T A L
Sbjct: 3350 RTSASL 3355



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG      C +     P   ++W + N  L  G +Y    + + + L +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVV 3243

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
             +   +DSG Y+C    S G  TTS +L  T
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVT 3270



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P  F +  KN    +G  A  + +L  N    V W +    L + ++YS+R  +      
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLR--QDGTKCE 3592

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163
            L I+ +   D GEY+C    +   A+ +V   P
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALP 3625



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 4/83 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  + N   +EG     +C +  +      +EW   ++ L  G RY    D +   L I
Sbjct: 3804 FIEDVKNQEAREGATAVLQCELSKAAP----VEWRKGSETLRGGDRYSLRQDGTRCELQI 3859

Query: 2836 THTYEEDSGIYTCKATNSKGSAT 2858
                  D+G Y+C     + SAT
Sbjct: 3860 HGLSVADTGEYSCVCGQERTSAT 3882



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 9/102 (8%)

Query: 1690 QLEDTSKY-----QRHSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLR 1743
            Q EDT +Y      + ++    +T APV F   ++   V E   AH    L   G     
Sbjct: 3952 QREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAG---AS 4008

Query: 1744 VEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785
            VEW +  + +    +   + D     L ++ V  ED+G YTC
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC 4050



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG-HR 1358
            Q R  + V + P F   L +     G  V L CR+   G     + W+ +GK ++   H 
Sbjct: 6003 QQRLALPVWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHH 6060

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                      AL L S+   DSG Y C A +  G   T
Sbjct: 6061 ILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCST 6098



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 943  VEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+ V+     I      G  AL + S+T  D+G Y C A +A G  +T   + +
Sbjct: 6045 ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104


>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
           calmodulin and titin-interacting RhoGEF protein.
          Length = 6620

 Score =  124 bits (300), Expect = 6e-27
 Identities = 89/325 (27%), Positives = 141/325 (43%), Gaps = 14/325 (4%)

Query: 245 VGESDVQISTEIDRSLGPVSP-PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
           +GE+   +  ++D         P    +P + +++EG++A F+ ++ G+PRP V+W K+G
Sbjct: 88  IGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDG 147

Query: 304 QRLINSNKHEIITTH--NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP--- 358
           +RL   +   +        + LR+R  +  D G Y + AENP G    +  L V+S    
Sbjct: 148 RRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD 207

Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
           T S      +  +   Q+R    R E +  +      + C    VTEGK  R  C VTG 
Sbjct: 208 TASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCT---VTEGKHARLSCYVTGE 264

Query: 419 PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
           P PE  W  + + + +   H +  +   N  L I     SD G+ TC A N  G+T +  
Sbjct: 265 PKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT-YSS 323

Query: 479 RLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
            L V+ +  V    F +R   L VRE E        V  P+    W K+   +  + +  
Sbjct: 324 VLVVVREPAV---PFKKRLQDLEVREKESATFLCE-VPQPSTEAAWFKEETRLWASAKYG 379

Query: 539 IHTDGGASTLDIPRAKASDAAWYQC 563
           I  +G    L +    A D A Y C
Sbjct: 380 IEEEGTERRLTVRNVSADDDAVYIC 404



 Score =  122 bits (293), Expect = 4e-26
 Identities = 100/341 (29%), Positives = 149/341 (43%), Gaps = 44/341 (12%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLL 4572
            P F    QN  V  G  V  D  VTG     V W K+GK ++ D    I E+  G + L+
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK-DKPKPQTKAAN----------- 4620
            I    P D G Y C+A NS G +   AE  V L +T  D     T++++           
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245

Query: 4621 ------------APPEIIEPLKDKIVAEGQAI-EFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                          P+++E L+D  VA G  + +F  K+ G P P + W+K  + +  S 
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA---- 4723
            + +M+     +TL I     ED G Y     N+ G    +A+L V  PD+ +  PA    
Sbjct: 5306 HIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVH 5365

Query: 4724 --LTPLRDI------VVYEGQPAQFKTQITSKIKPTIQWLREGA------LIPETPDFQM 4769
              L P R +       V +G    F  ++  +  PT+ WLRE A      + P+TP + +
Sbjct: 5366 EQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV 5425

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                    L++ +   +  GT+TC A+ AAGQ   SA L V
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score =  103 bits (248), Expect = 1e-20
 Identities = 92/342 (26%), Positives = 141/342 (41%), Gaps = 30/342 (8%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--TL 323
            P    + +N ++Q+G    F   ++G P P V WFK+G +L+  + H +I         L
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDG-KLLEEDDHYMINEDQQGGHQL 5184

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY--VQD--QRSQYITDT---QQ 376
             +     +D G Y  LAEN  G   T   L V+  +  Y    D  + S Y +       
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244

Query: 377  RETEERIEISEKALAPQFVKVCQDRDVTEG-KMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            RE E     +++   PQ V+  +D  V  G ++ +F  +V G P P + WF  D Q    
Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF-KDGQPLTA 5303

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI------EK---- 485
              H  + ++   H L I +VT  DSG       N  G      RL V       EK    
Sbjct: 5304 SAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASD 5363

Query: 486  --EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPII--PNPEL 537
              EQ+V P+ +ERF+   V++G  +  + +  G P P + W ++    GV  I    P  
Sbjct: 5364 VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423

Query: 538  RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             + +     +L +          Y C A N AG     A L+
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLH 5465



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 103/424 (24%), Positives = 163/424 (38%), Gaps = 31/424 (7%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            S  P F  + +   V   + A    +  G P P + W ++  P+     F++        
Sbjct: 7    SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I  + + DS  +   A N  G A  +  L V+ +          P F L   ++ V  
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA---PHFLLRPTSIRVRE 123

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKV-QPDIRNKILEEDGTYTLL-ILEAYPQDSGKYE 4585
            G       +V G+    V W K+G+++ +PD     +EE G  + L I  A P+D G YE
Sbjct: 124  GSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYE 183

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQT----------------KAANAPPEIIEP- 4628
              A N  G A   A  VV   A     +P T                +A  AP       
Sbjct: 184  VRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTG 243

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-YTLRISEAFP 4687
             +   V EG+    SC + G+P P   W K  +L+   +   +   A E + L+I     
Sbjct: 244  TRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ 303

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
             D G Y C A N  G+   +  + V +P     +P    L+D+ V E + A F  ++   
Sbjct: 304  SDRGLYTCTASNLVGQTYSSVLVVVREP----AVPFKKRLQDLEVREKESATFLCEVPQP 359

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
                  W +E   +  +  + +  EG    L + N   +D   + C   T  G   T A+
Sbjct: 360  -STEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE--TPEGS-RTVAE 415

Query: 4808 LVVK 4811
            L V+
Sbjct: 416  LAVQ 419



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 87/334 (26%), Positives = 132/334 (39%), Gaps = 30/334 (8%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP+F+   +   V+ GK     C++ G P P+V+W  + + +      + L  +   + L
Sbjct: 9   APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFR-LAQDGDLYRL 67

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVERFSTLNVREGEPV 508
            I ++ L DSG   C ARN  GE      L V  +      AP F+ R +++ VREG   
Sbjct: 68  TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEA 127

Query: 509 VLNARAVGTPTPRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
               R  G+P P ++W KDG  +     P +R+   G AS L I  A+  D   Y+  A+
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187

Query: 567 NVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIP 626
           N  G+ +  A L                  RP                L H++R R  + 
Sbjct: 188 NPLGAASAAAALVVDSDAADTAS-------RP---------GTSTAALLAHLQRRREAM- 230

Query: 627 PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686
              E     PP      ++ T  EG   H        G+P  +  W K+GQ +    R  
Sbjct: 231 -RAEGAPASPPS--TGTRTCTVTEGK--HARLSCYVTGEPKPETVWKKDGQLVTEGRRHV 285

Query: 687 SIFRFGY--ISLDMLSLNIQDSGEYTCRAVSATG 718
            ++        L +L     D G YTC A +  G
Sbjct: 286 -VYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 8/194 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP+  E L D     G+ ++ +C++ G P P + WYK  K ++   +  +    D     
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 4682 ISEAFPE-DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I ++    D G Y C A ++AG  +   K+ V  P +  N    +P       EG+ AQF
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPF-----VEGEDAQF 6127

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRATTA 4798
               I     P I+W ++GAL+     FQ + E  +   VL+I    +ED G + C     
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187

Query: 4799 AGQVETSAKLVVKS 4812
             G    SA+L ++S
Sbjct: 6188 LGSARASAELRIQS 6201



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 57/208 (27%), Positives = 103/208 (49%), Gaps = 8/208 (3%)

Query: 4514 PSFTLTAQNVNVTSG-QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            P      +++ V  G +L +   KV G     +YW K+G+ +      ++ ++   +TL 
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLP-ATKDKPKPQTKAANAPPEIIEPLKD 4631
            I+    +DSG+Y     N+ G A   A  +V  P   ++KP         PP ++E    
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTP 5379

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWY-----KGDKLIKP-SKYFQMSRTADEYTLRISEA 4685
            K V +G +I FS K+ G+P+PTV W      +G   I P +  + ++ +A +++L + + 
Sbjct: 5380 KKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDV 5439

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
              + +G Y C+A N+AG+   +A L V+
Sbjct: 5440 GRQHQGTYTCIASNAAGQALCSASLHVS 5467



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIRNKILEE-DGTYT 4570
            PP F     +     G+ V+L  +VTGT KP+ + W K+GK VQ D  + ++E+ DG+  
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPV-ISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L++      DSG+Y C A ++AG      + +V +P                P  +  ++
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP----------------PRFVNKVR 6115

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--MSRTADEYTLRISEAFPE 4688
                 EG+  +F+C I G P P ++WYK   L+     FQ      +    L I  A  E
Sbjct: 6116 ASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKE 6175

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            D G Y+C   N  G    +A+L++  P
Sbjct: 6176 DLGLYECELVNRLGSARASAELRIQSP 6202



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/230 (29%), Positives = 107/230 (46%), Gaps = 9/230 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT-SIFRFGYIS 695
            P F+  L++    +G  + F+  +   G P   + W K+G+ +E    +  +  + G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT-IERTSQHPETLQYIQQLEDYS 754
            L + ++   D G Y C A ++ GV+ TKA L V   +T  +  +   E+  Y    + Y 
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA-QGYL 5242

Query: 755  KYQHQESIEEQTS--QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
              + QE  E  T   Q PQ +  L+DL      R A F  QL     P  R+ W+KDG+P
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKF--QLKVKGYPAPRLYWFKDGQP 5300

Query: 813  ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +TAS+ I         +L I+ +  ED+G Y     N +G A S+A + V
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 60/202 (29%), Positives = 92/202 (45%), Gaps = 5/202 (2%)

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
            Q + + AP  +  P K  +V+ G+    SC+IVG P P V W K  + +     F++++ 
Sbjct: 3    QPQFSGAPRFLTRP-KAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNLP-ALTPLRDIVV 4732
             D Y L I +    D G Y C A N+ G    A  L+V  +   A+  P  L     I V
Sbjct: 62   GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRV 121

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALI--PETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             EG  A F+ ++    +P + W ++G  +  P+ P  ++   G  + L I      D GT
Sbjct: 122  REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181

Query: 4791 FTCRATTAAGQVETSAKLVVKS 4812
            +  RA    G    +A LVV S
Sbjct: 182  YEVRAENPLGAASAAAALVVDS 203



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 92/364 (25%), Positives = 153/364 (42%), Gaps = 26/364 (7%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYV 1768
            APVF   +++  V +     F+   +  G P   V W ++G  +E  +      D  G  
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQ--LESQHESALQKIQQLED 1826
             L +  V P D G Y C A N +G + T + L V   ++         ES+     Q   
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
            SSR Q   +      Q P+ + +L         + A ++ +++ YP P  R+ W+ +G+ 
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYWFKDGQP 5300

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946
            L +    R ++      L+I++V  EDSG+Y     N +G A SS RL V+  +    + 
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD----EP 5356

Query: 1947 QHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND 2006
            + + A +  + L      +R      F  +K + G  I  +   EG PV     L    +
Sbjct: 5357 EEKPASDVHEQLVPPRMLER------FTPKKVKKGSSITFSVKVEGRPVPTVHWLR--EE 5408

Query: 2007 PTMRVEWYCNGRPVQQGHRF-KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
                V W     P   G+    +      V LD+     +  GTY C A+NA G+A+ ++
Sbjct: 5409 AERGVLWI---GPDTPGYTVASSAQQHSLVLLDV---GRQHQGTYTCIASNAAGQALCSA 5462

Query: 2066 SVKV 2069
            S+ V
Sbjct: 5463 SLHV 5466



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F +   D     G+  +  CRVTG P P ++W+ + + ++ D +H ++ +  G+ AL+
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            + ++T  DSG   C A + +G  +   ++ V      V P+FV +       EGE     
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFT 6128

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVA 569
                G P P+I W KDG  +    + +  ++   G   L I  A   D   Y+C   N  
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188

Query: 570  GSTATRARL 578
            GS    A L
Sbjct: 6189 GSARASAEL 6197



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 61/258 (23%), Positives = 111/258 (43%), Gaps = 22/258 (8%)

Query: 266  PKIAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P++ ++ R+ ++  G   A+FQ+++ G P PR+ WFK+GQ L  S    +       TL 
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            + +  + DSG Y     N  G   +S  L V  P E                 E +   +
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEP----------------EEKPASD 5363

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-----IRDDYNHK 439
            + E+ + P+ ++    + V +G    F  +V GRP P V W   + +     I  D    
Sbjct: 5364 VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423

Query: 440  ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
             + + +  H+L++ +V     G  TC+A N +G+      L+V    +V   + V+    
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 5483

Query: 500  LNVREGEPVVLNARAVGT 517
                +G    ++A+ + T
Sbjct: 5484 STFLQGTTQAISAQGLET 5501



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 90/406 (22%), Positives = 162/406 (39%), Gaps = 48/406 (11%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T  +Q     E   A F  E   E    ++W     P+ N    +I     +  L+++ +
Sbjct: 2561 TGPLQDAEATEEGWASFSCELSHEDEE-VEWSLNGMPLYNDSFHEISHKGRRHTLVLKSI 2619

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
               D+ +       R  + K S +  +E +       + P  F     +++      + L
Sbjct: 2620 QRADAGIV------RASSLKVSTSARLEVR-------VKPVVFLKALDDLSAEERGTLAL 2666

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              +V+  +   V W K+G ++ P  +   L   GT  L++ +  P+D+G Y C   +   
Sbjct: 2667 QCEVSDPEA-HVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEET 2725

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR                    +  +    I + LK   V EG++  F C +  +    
Sbjct: 2726 RAR-------------------VRVHDLHVGITKRLKTMEVLEGESCSFECVLSHESASD 2766

Query: 4654 -VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
               W  G K +  S  FQ +R   +Y L + EA P D G+   V ++  G +T  A L V
Sbjct: 2767 PAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGE---VVFSVRG-LTSKASLIV 2822

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
             +   A     + PL D  V  G+  + + +++    P + WL++   I ++  + ++ E
Sbjct: 2823 RERPAA----IIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCE 2877

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRA----TTAAGQVETSAKLVVKSKT 4814
            G  A+L+I     +D G +TC      +TA+  VE  A    +  T
Sbjct: 2878 GTMAMLVIRGASLKDAGEYTCEVEASKSTASLHVEEKANCFTEELT 2923



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 9/231 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYVA 2036
            P F   ++N EV +G+PV  +  +T    P   V W+ +G+ +++   +    D  G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096
            L I      D G Y C A N++G + T + ++VD  S  Y    D          + Y  
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243

Query: 2097 PKPIEEEQP----GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
             +  E  +     GQ P  +  L  L+       A F+ +V+    P L   WF +GQ +
Sbjct: 5244 SREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLY--WFKDGQPL 5301

Query: 2153 RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
             A    R T       L+I+    EDSG Y    +N +G A ++  L V G
Sbjct: 5302 TASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 100/393 (25%), Positives = 157/393 (39%), Gaps = 53/393 (13%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSILIIRQVFVEDSAV 4480
            V E   A F           + W+ +  P+  +   +I        +L +RQ+ ++DS  
Sbjct: 3016 VQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGT 3075

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
                A    G  + SA L V EK         P  F+    +  +T G+ + L  + T T
Sbjct: 3076 IYFEA----GDQRASAALRVTEK---------PSVFSRELTDATITEGEDLTLVCE-TST 3121

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
              I V W K+GK ++   R ++  E     LLI  A  QDSG+Y+C     AG A C + 
Sbjct: 3122 CDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC----EAGGA-CSSS 3176

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             V              +    P    E LKD  V EG A    C +     P V+W  G+
Sbjct: 3177 IV--------------RVHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGN 3221

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
             +++P   + + +      L +    P+D G Y C    S G  T +A L VT       
Sbjct: 3222 NVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTA------ 3271

Query: 4721 LPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778
            LPA  +  LR+    EG  A  + ++ SK  P ++W +    + +   + +  +G    L
Sbjct: 3272 LPAQFIGKLRNKEATEGATATLRCEL-SKAAP-VEWRKGSETLRDGDRYCLRQDGAMCEL 3329

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             I      D   ++C      G+  TSA L ++
Sbjct: 3330 QIRGLAMVDAAEYSC----VCGEERTSASLTIR 3358



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 106/440 (24%), Positives = 180/440 (40%), Gaps = 56/440 (12%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            I R++ + +  EI+  A+  E   +  VK   P    + ++     E  +   E +    
Sbjct: 2258 IYRRVLAEDAGEIQFVAENAESRAQLRVK-ELPVTLVRPLRDKIAMEKHRGVLECQVSRA 2316

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
                ++W++ +  ++  P +++ +      LII  V  ED   +   A    G  K SA 
Sbjct: 2317 SAQ-VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQ 2371

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVT--SGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              VEE+      G+         Q+V V   +      +T +   +P    WL  GK V 
Sbjct: 2372 FFVEEQSITIVRGL---------QDVTVMEPAPAWFECETSIPSVRPPK--WLL-GKTVL 2419

Query: 4556 PDIRNKILEEDGT-YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                N  LE++GT + L++       +G        + G++R  A  VVS          
Sbjct: 2420 QAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHF----TVGKSRSSARLVVS---------- 2465

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSR 4673
                 + P  +  PL+ K   E Q++  SC    +P P  VQWYK D  + PS+ F+MS 
Sbjct: 2466 -----DIPVVLTRPLEPKTGRELQSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSL 2518

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  LRI    P D G Y+C     AG    + ++ V    +A  +    PL+D    
Sbjct: 2519 EGQMAELRILRLMPADAGVYRC----QAGSAHSSTEVTV----EAREVTVTGPLQDAEAT 2570

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            E   A F  +++ +    ++W   G  +      ++ H+G    L++ +    D G    
Sbjct: 2571 EEGWASFSCELSHE-DEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG--IV 2627

Query: 4794 RATTAAGQVETSAKLVVKSK 4813
            RA++   +V TSA+L V+ K
Sbjct: 2628 RASSL--KVSTSARLEVRVK 2645



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 69/232 (29%), Positives = 99/232 (42%), Gaps = 13/232 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI-EASNRLTTMHDFGY 1767
            QAP F +    IRV E   A F  R+   G P+  V W ++G  + E       + + G 
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRV--GGSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165

Query: 1768 V-ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLED 1826
              AL ++   P D GTY  RA N LG A  ++ L V S A+        S    +  L+ 
Sbjct: 166  ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ- 224

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                +RRE +      A    T     T ++EG+ A   C +   P P     W  +G++
Sbjct: 225  ----RRREAMRAEGAPASPPSTGTRTCT-VTEGKHARLSCYVTGEPKP--ETVWKKDGQL 277

Query: 1887 LQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            +  G R+    D      L IL     D G YTC A N +GQ  SS+ + V+
Sbjct: 278  VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 92/386 (23%), Positives = 153/386 (39%), Gaps = 38/386 (9%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-TETNNFGFV 1635
            AP+  T L+N E+++G    F+   +        V W+ + K L+    +    +  G  
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFD--CVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY----LESQHEGALPRLNQL 1691
             L I + +P D G Y C A N++G + T     V    + Y      ++          L
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAE-NQAAHFEARLIPVGDPKLRVEWLRNG 1750
                +    S  DE   Q P     ++D++VA   + A F+ ++   G P  R+ W ++G
Sbjct: 5243 SSREQEGTESTTDE--GQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKDG 5298

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             P+ AS  +          L +  V  EDSG Y     N +G A +S+ L V+       
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD---- 5354

Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870
            E + + A    +QL                   PR + +   P K+ +G S  +  ++E 
Sbjct: 5355 EPEEKPASDVHEQL-----------------VPPRMLERFT-PKKVKKGSSITFSVKVEG 5396

Query: 1871 YPDPNMR-VEWYFNGKVLQSG---HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             P P +  +       VL  G     Y  ++     +L +L V  +  G YTC A N  G
Sbjct: 5397 RPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG 5456

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESAL 1952
            QA+ S  L+V     +    + + AL
Sbjct: 5457 QALCSASLHVSGLPKVEEQEKVKEAL 5482



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 84/325 (25%), Positives = 133/325 (40%), Gaps = 22/325 (6%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F T  K  V +S G+ A     ++  G+ +  + W  + + + A  R R      +  
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQIV--GNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKG---QKPRFTTHIQNIEGLKDG 3164
            L IL     DSG Y CRA N  G+A  +V L+ VD       Q P F     +I  +++G
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQ-VDAEAACAEQAPHFLLRPTSIR-VREG 124

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRH--STRIKTVSDFGFV-VLDIAYTQNHDSGE 3221
              A F C V     P   + W  +G+ +      R++ V + G    L I   +  D G 
Sbjct: 125  SEATFRCRV--GGSPRPAVSWSKDGRRLGEPDGPRVR-VEELGEASALRIRAARPRDGGT 181

Query: 3222 YVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            Y  RA N  G     A +                + A +  L+  + A  +    P A P
Sbjct: 182  YEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA-MRAEGAP-ASP 239

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIV 3340
            P   T+   VT   EG+ A     +    +P  +  W  +G+ +  G R+  + D     
Sbjct: 240  PSTGTRTCTVT---EGKHARLSCYV--TGEPKPETVWKKDGQLVTEGRRHVVYEDAQENF 294

Query: 3341 ILDILYCYEENSGEYECVATNKLGR 3365
            +L IL+C + + G Y C A+N +G+
Sbjct: 295  VLKILFCKQSDRGLYTCTASNLVGQ 319



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 63/233 (27%), Positives = 101/233 (43%), Gaps = 7/233 (3%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S + PVF+  L N   V +G  +  +C +   G P   V WF +G+ +     +    D 
Sbjct: 5122 SDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQL 1290
             G   L I     AD G Y   A N +G + T A +RV +  +D  T     ++      
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238

Query: 1291 LEDAARRTKQVREDITVM-QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN 1349
                + R ++  E  T   Q PQ    L +++   GT +  + +L+  G    R+ WF +
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFKD 5297

Query: 1350 GKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            G+P+      R   +     L+++SV  EDSG Y    +N +G A +S  L V
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 34/92 (36%), Positives = 54/92 (58%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F+   Q+++V +G    FDC VTG+P P V WF + + + +D ++ I  ++ G H L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            +IT V  +D GV  C+A N  G ++ +  L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 65/220 (29%), Positives = 94/220 (42%), Gaps = 15/220 (6%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT--GSRVHTLNDFGFIALDIDYIY 3761
            +I V EG    F CRV   G P   + W  +GR      G RV         AL I    
Sbjct: 118  SIRVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAAR 175

Query: 3762 ARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPK 3821
             RD G Y  RA N  G+A+  A +   +  D    +  P   +   +  L+R R  +A +
Sbjct: 176  PRDGGTYEVRAENPLGAASAAAALVVDS--DAADTASRPGTSTAALLAHLQRRR--EAMR 231

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
             E   ++PP   T  ++ TV E +  R  C V    +PK    W ++G+L+  G R+   
Sbjct: 232  AEGAPASPPS--TGTRTCTVTEGKHARLSCYVTG--EPKPETVWKKDGQLVTEGRRHVVY 287

Query: 3882 YDM--GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             D    FV L IL+    D G Y C A N  G+ ++   +
Sbjct: 288  EDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 57/200 (28%), Positives = 88/200 (44%), Gaps = 14/200 (7%)

Query: 4428 ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAEN 4487
            A+F+++  G P P + W+++  P+  S   ++        L I  V  EDS  +AA   N
Sbjct: 5278 AKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISN 5337

Query: 4488 RGGTAKCSANLVV------EEKRRQG-RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
              G A  SA L+V      EEK        +VPP          V  G  +    KV G 
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR 5397

Query: 4541 KPIDVYWLKNGKK-----VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
                V+WL+   +     + PD     +      ++L++L+   Q  G Y C+A N+AG+
Sbjct: 5398 PVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457

Query: 4595 ARCDAECVVS-LPATKDKPK 4613
            A C A   VS LP  +++ K
Sbjct: 5458 ALCSASLHVSGLPKVEEQEK 5477



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 79/288 (27%), Positives = 115/288 (39%), Gaps = 19/288 (6%)

Query: 1835 DVEVA-VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL--QSGH 1891
            D E A   QAP F+ +     ++ EG  A + CR+   P P   V W  +G+ L    G 
Sbjct: 100  DAEAACAEQAPHFLLRPTS-IRVREGSEATFRCRVGGSPRP--AVSWSKDGRRLGEPDGP 156

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
            R R       +AL I      D G Y  +A N LG A ++  L V S  +        S 
Sbjct: 157  RVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTST 216

Query: 1952 LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
               + +L+   R + A++ +      P  G   +   VTEG    L   +T   +P    
Sbjct: 217  AALLAHLQ---RRREAMRAEGAPASPPSTGT--RTCTVTEGKHARLSCYVT--GEPKPET 269

Query: 2012 EWYCNGRPVQQGHRFKTTYDFGY-VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             W  +G+ V +G R     D      L IL+    D G Y C A+N VG+  T SSV V 
Sbjct: 270  VWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ--TYSSVLVV 327

Query: 2071 AKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSL 2118
             +         ++RL+ ++  EK       E  QP     +    T L
Sbjct: 328  VREPA---VPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRL 372



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 32/108 (29%), Positives = 60/108 (55%), Gaps = 1/108 (0%)

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
            P    +P P    ++A P  +  L+++ V +G  + F C + G+P+P+V+W+K  KL++ 
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEE 5168

Query: 4666 SKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
              ++ ++      + L I+   P D G Y+C+A NS G  +  A+L+V
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 7/239 (2%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SL 2833
            VF++ L N   ++G  + F+C V  +  P   + WF + K L     Y    D      L
Sbjct: 5127 VFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             IT     D G+Y C A NS G ++T   LR       Y         +   + +    +
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
            R  +G   +  + + P+   ++    + Q+  G  L  + Q++ K  P  ++ W+ +G+ 
Sbjct: 5245 REQEGTESTTDEGQLPQ---VVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFKDGQP 5300

Query: 2954 LEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
            L   +  ++T      TL+++ V   DSG Y     N  G A++S+ +     D   E+
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEK 5359



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 95/421 (22%), Positives = 163/421 (38%), Gaps = 45/421 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +F KK++P  V E      EVE    P P ++W R    +    + +IH    +  L+
Sbjct: 1987 PVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  V   D   F     +     K  A L VE ++ +   G+   +     Q       Q
Sbjct: 2046 LHNVGFADRGFFGCETPDD----KTQAKLTVEMRQVRLVRGL--QAVEAREQGTATMEVQ 2099

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
            L   D        +D  W ++G + Q      +      +TL +    P+DSG     A 
Sbjct: 2100 LSHAD--------VDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAE 2151

Query: 4590 NSAGEARCDA-ECVVSLP------ATKDKPKPQTKAANAPPEI-IEPLKDKI-VAEGQAI 4640
                 AR    E  VS         T +K K   +   + P + +  LKD + +  G+ +
Sbjct: 2152 GVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTM 2211

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD------EYTLRISEAFPEDEGDYK 4694
              + +   + L   +    D+ +          +A        YTL       ED G+ +
Sbjct: 2212 AIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQ 2271

Query: 4695 CVAYNSAGRVTVAAK-LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
             VA N+  R  +  K L VT          + PLRD +  E      + Q+ S+    ++
Sbjct: 2272 FVAENAESRAQLRVKELPVT---------LVRPLRDKIAMEKHRGVLECQV-SRASAQVR 2321

Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            W +    +   P ++++ +G    L+I + + ED  T+TC     AG V+TSA+  V+ +
Sbjct: 2322 WFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTC----DAGDVKTSAQFFVEEQ 2377

Query: 4814 T 4814
            +
Sbjct: 2378 S 2378



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 84/370 (22%), Positives = 146/370 (39%), Gaps = 47/370 (12%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W + +  ++    + +    T+  L I  + V D+  ++ V     G  + SA L V 
Sbjct: 3831 VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVR 3886

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
              +         P F    Q++    G    L  +++      V W K G ++Q + R +
Sbjct: 3887 APQ---------PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKGGLQLQANGRRE 3936

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
               +  T  L++ +   +D+G+Y C   + A  A        +L  T            A
Sbjct: 3937 PRLQGCTAELVLQDLQREDTGEYTCTCGSQATSA--------TLTVTA-----------A 3977

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   +  L+ + V EG      C++  +   +V+W KG   + P   +QM +      L 
Sbjct: 3978 PVRFLRELQHQEVDEGGTAHLCCEL-SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELL 4036

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            +     ED GDY C      G     A L V  P         T L+ +    G  A+  
Sbjct: 4037 VRGVEQEDAGDYTC----DTGHTQSMASLSVRVPRPKFK----TRLQSLEQETGDIARLC 4088

Query: 4742 TQIT-SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             Q++ ++    +QWL+EG  +   P ++M  +G    LLI     +DTG + C      G
Sbjct: 4089 CQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC----VTG 4144

Query: 4801 QVETSAKLVV 4810
              +T+A L V
Sbjct: 4145 GQKTAASLRV 4154



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 99/448 (22%), Positives = 173/448 (38%), Gaps = 45/448 (10%)

Query: 4349 DPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPS 4408
            DP+  TV GK V  + + Q  ++      + R+   ++  E+    +         V+  
Sbjct: 2766 DPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVR-E 2824

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P    K ++   V   E      E      P + W ++   I+ S  + +    T ++L
Sbjct: 2825 RPAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAML 2883

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +IR   ++D+  +    E     +K +A+L VEEK            FT    N+ V   
Sbjct: 2884 VIRGASLKDAGEYTCEVE----ASKSTASLHVEEKAN---------CFTEELTNLQVEEK 2930

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                   K T      V W K   +++   +++  +E  T  L I      DS  Y C  
Sbjct: 2931 GTAVFTCK-TEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTC-- 2987

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
                G+A+  A+ +V           Q +  +    IIE L+D  V EG +  F C+I  
Sbjct: 2988 --DIGQAQSRAQLLV-----------QGRRVH----IIEDLEDVDVQEGSSATFRCRISP 3030

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                 V W+     +  ++  ++      Y  L + +   +D G      Y  AG    +
Sbjct: 3031 ANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG----TIYFEAGDQRAS 3086

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            A L+VT+     +      L D  + EG+      + TS     + W ++G  +  +   
Sbjct: 3087 AALRVTEKPSVFS----RELTDATITEGEDLTLVCE-TSTCDIPVCWTKDGKTLRGSARC 3141

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            Q+ HEG+ A LLI     +D+G + C A
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEA 3169



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 81/369 (21%), Positives = 144/369 (39%), Gaps = 49/369 (13%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W++ +  +++     +     +  L IR +  ED+  +  +     G  + SA L V 
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVR 3710

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
                      +P  F    +N   T G    L  +++   P++  W K  + ++   R+ 
Sbjct: 3711 A---------MPSKFIEGLRNEEATEGDTATLWCELSKAAPVE--WRKGHETLRDGDRHS 3759

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            + ++     L I      D+G+Y CV     G+ R  A   V                  
Sbjct: 3760 LRQDGSRCELQIRGLAVVDAGEYSCVC----GQERTSATLTVRA---------------L 3800

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   IE +K++   EG      C++  K  P V+W KG + ++    + + +      L+
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQ 3858

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I      D G+Y CV     G+   +A L V  P          PL+ +   EG  A  +
Sbjct: 3859 IHGLSVADTGEYSCV----CGQERTSATLTVRAPQPVFR----EPLQSLQAEEGSTATLQ 3910

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             ++ S+   T+ W + G  +      +   +G  A L++ +   EDTG +TC      G 
Sbjct: 3911 CEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC----TCGS 3965

Query: 4802 VETSAKLVV 4810
              TSA L V
Sbjct: 3966 QATSATLTV 3974



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 47/198 (23%), Positives = 82/198 (41%), Gaps = 9/198 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + + R ++  +      ++  +D DV EG    F CR++   Y  V WF++   +  +  
Sbjct: 2991 QAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANEL 3050

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
            ++I     G H L +  + L DSG +      ++G+      L V EK  V    F    
Sbjct: 3051 NEIDAQPGGYHVLTLRQLALKDSGTIYF----EAGDQRASAALRVTEKPSV----FSREL 3102

Query: 498  STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            +   + EGE + L         P + W KDG  +  +   ++  +G  + L I  A   D
Sbjct: 3103 TDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQD 3161

Query: 558  AAWYQCTAQNVAGSTATR 575
            +  Y+C A     S+  R
Sbjct: 3162 SGRYKCEAGGACSSSIVR 3179



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 117/538 (21%), Positives = 213/538 (39%), Gaps = 53/538 (9%)

Query: 4280 KLQELENEQVIKESRLRESTHQYAIP-GDKVTSNTVAKSMAQ-RYEDNLDQTEEVTEQRV 4337
            +LQ    E V+++ + RE T +Y    G + TS T+  + A  R+   L Q +EV E   
Sbjct: 3938 RLQGCTAELVLQDLQ-REDTGEYTCTCGSQATSATLTVTAAPVRFLREL-QHQEVDEGGT 3995

Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQ 4397
                 +  R     E      ++    + Q  ++    + + R +   +  +        
Sbjct: 3996 AHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHT 4055

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEF-DGEPLPLIKWYRENFPIKNSPD 4456
            + +    V+  +P  F  ++Q       + AR   +  D E   +++W +E   +   P 
Sbjct: 4056 QSMASLSVRVPRPK-FKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPK 4114

Query: 4457 FQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
            +++ +      L+I Q+  +D+  +A V     G  K +A+L V E       G+V    
Sbjct: 4115 YEMRSQGATRELLIHQLEAKDTGEYACVT----GGQKTAASLRVTEPEVTIVRGLV---- 4166

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLILE 4575
                 +  VT+ + V    +V+      V W   G  +Q +   ++   DG  +TL +  
Sbjct: 4167 -----DAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKG 4221

Query: 4576 AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA 4635
              P+D+G       N A  A    +  V  P                  I+EPL+D  ++
Sbjct: 4222 VTPEDAGTVSFHLGNHASSA----QLTVRAPEVT---------------ILEPLQDVQLS 4262

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            EGQ   F C++        +W  G   ++ ++   +  T ++ TL +         D   
Sbjct: 4263 EGQDASFQCRLSRASGQEARWALGGVPLQANEMNDI--TVEQGTLHLLTLHKVTLEDAGT 4320

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            V+++  G  +  A+LKVT    A N   +  L ++   EG  A F+ Q++        WL
Sbjct: 4321 VSFH-VGTCSSEAQLKVT----AKN-TVVRGLENVEALEGGEALFECQLSQPEVAAHTWL 4374

Query: 4756 REGALI--PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +   +   E  +      G   +LL+ N   +D    +CR T  AG + TSA L V+
Sbjct: 4375 LDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQD----SCRVTFLAGDMVTSAFLTVR 4428



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 103/439 (23%), Positives = 178/439 (40%), Gaps = 54/439 (12%)

Query: 2043 YAEDTGTYMCKATNAVGEA--VTTSSVKVDAKSGLYLDT-LDEQRLKKIQELEKYERPKP 2099
            Y ED   ++C    A+ EA    T   ++ A  G+ ++  L EQ  ++++     E P P
Sbjct: 5051 YREDEH-FICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPAP 5109

Query: 2100 IEEEQP-------GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
            +   +P          PVFLT L + E +++G    F+C V     P  ++ WF +G+ +
Sbjct: 5110 VVPPEPLPSLLTSDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLL 5166

Query: 2153 RAGHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
                 Y    D  G   L I      D G Y C A N +G +     L+V    +   DT
Sbjct: 5167 EEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV-DLTSTDYDT 5225

Query: 2212 QHPNGLEKIRQLEAQGHSTRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQV 2266
               +  E      AQG+ +  E E  + +      P+ V ELR        + A F+ +V
Sbjct: 5226 A-ADATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV 5284

Query: 2267 EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHC 2326
            +    P  R+ ++ +G+ L ++A   +T      +L+I     ED+G+Y+    NA+G  
Sbjct: 5285 KGYPAP--RLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342

Query: 2327 TSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNID 2386
             S+  + V              G ++  E  +++  ++   P  + R  P          
Sbjct: 5343 YSSARLLV-------------RGPDEPEEKPASDVHEQLVPPRMLERFTP---------K 5380

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK------LIEDSSRITKTHDFGYVSMTISH 2440
             +++G +  F  ++   G P   V W R E       +  D+   T        S+ +  
Sbjct: 5381 KVKKGSSITFSVKV--EGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLD 5438

Query: 2441 VRDEDEGVYMCRASNLLGE 2459
            V  + +G Y C ASN  G+
Sbjct: 5439 VGRQHQGTYTCIASNAAGQ 5457



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 86/408 (21%), Positives = 164/408 (40%), Gaps = 42/408 (10%)

Query: 4390 IEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449
            IE   + + R   G +  +KPP    +    R+  HE+A+   E   +    + W ++  
Sbjct: 689  IESSIRMEVRAAPG-LTANKPPAAAAREVLARL--HEEAQLLAELSDQAAA-VTWLKDGR 744

Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
             +   P +++   + + +L++R V  +D+ ++  V+  RGG  + +  L V     QG  
Sbjct: 745  TLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVS--RGG--RIAYQLSV-----QGLA 795

Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT- 4568
              +     +    V+  +G   + + + T    + V+W K+G ++       + E+ GT 
Sbjct: 796  RFLHKD--MAGSCVDAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTR 852

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            + L+      QD G Y C      GE   D    VS P          K   A  ++   
Sbjct: 853  HRLVAATVTRQDEGTYSC----RVGEDSVDFRLRVSEP----------KVVFAKEQLA-- 896

Query: 4629 LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
             + K+ AE G +   SC+ V +    V WYK  K +  S    M  T     L + +A  
Sbjct: 897  -RRKLQAEAGASATLSCE-VAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQ 954

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
             D G+Y C     AG   ++  L V +P        +    ++    G  A    ++ ++
Sbjct: 955  ADAGEYSC----EAGGQRLSFHLDVKEPKVVFAKDQVAH-SEVQAEAGASATLSCEV-AQ 1008

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
             +  + W ++G  +  +    +  +G    L++    + D G ++C A
Sbjct: 1009 AQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 115/497 (23%), Positives = 193/497 (38%), Gaps = 63/497 (12%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+++   C +  +  P   + W  + K +    +Y    + +   L I     +D+G YT
Sbjct: 2841 GEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897

Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTE 2907
            C+   SK +A    SL      N + +         L+  E+       K   P+   T 
Sbjct: 2898 CEVEASKSTA----SLHVEEKANCFTEEL-----TNLQVEEKGTAVFTCKTEHPAATVT- 2947

Query: 2908 YPKPEWIIPIAAEHQ-LVEGQVLHLEGQVEPKNDPDLKI----EWYFNGKVLEQGSRFKL 2962
            + K    +  + +HQ   EG  L L      K D D       +     ++L QG R  +
Sbjct: 2948 WRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHI 3007

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA---FTSSTVYCTSKDNLIERTQHPKGT 3019
              D     L+ VDV E  S  + C+      E    F   T    ++ N I+    P G 
Sbjct: 3008 IED-----LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDA--QPGGY 3060

Query: 3020 EGLEKIQ-NLEDS--LRKEPGQQPDDDTGRPPEFTTVF-KDIVD--ISEGQIAHYEASLI 3073
              L   Q  L+DS  +  E G Q      R  E  +VF +++ D  I+EG+    + +L+
Sbjct: 3061 HVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE----DLTLV 3116

Query: 3074 -PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
              T    + + W  +GKT+  S R +  +      L I G    DSG Y C A      +
Sbjct: 3117 CETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSS 3176

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
             + V    V        RF   ++++E L +G +A   C +  V  P   ++W +    +
Sbjct: 3177 IVRVHARPV--------RFQEALKDLEVL-EGGAATLRCVLSSVAAP---VKWCYGNNVL 3224

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESL 3252
            R   +     +   + L +   +  DSG Y C     +G+  T AT+         + +L
Sbjct: 3225 RPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLT--------VTAL 3272

Query: 3253 QPDSLAKIRELESLQGA 3269
                + K+R  E+ +GA
Sbjct: 3273 PAQFIGKLRNKEATEGA 3289



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 91/367 (24%), Positives = 140/367 (38%), Gaps = 27/367 (7%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR-ITSIFNFGYV 828
            P F+  LQ+  E+Q+G    F+  +T    P   V W+KDG+ +      + +    G  
Sbjct: 5126 PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXX 888
             L I  +   D G Y   A N +G + + A +RV   ST   D                 
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTST---DYDTAADATESSSYFSAQ 5239

Query: 889  XXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKD 948
                           +  Q P+    ++D         A F+ +++  G    R+ W KD
Sbjct: 5240 GYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFKD 5297

Query: 949  GRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
            G+P+ AS+ I          L I SVT  D+G Y     NA+G A +SA L +V   D  
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL-LVRGPD-- 5354

Query: 1009 AESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVE 1068
             E +     +  + L       + T ++VK      F   ++G        + H+  R E
Sbjct: 5355 -EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR----PVPTVHW-LREE 5408

Query: 1069 PQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQ 1128
             +      V W   G          +      V LD+     +  G YT +A NAAG+A 
Sbjct: 5409 AERG----VLWI--GPDTPGYTVASSAQQHSLVLLDVG---RQHQGTYTCIASNAAGQAL 5459

Query: 1129 LSASMTV 1135
             SAS+ V
Sbjct: 5460 CSASLHV 5466



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 78/337 (23%), Positives = 123/337 (36%), Gaps = 56/337 (16%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+   +P+   +  G DA    Q+ GNP P+V+W K+ Q +    +  +    +   L +
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
            +    DSG Y   A N  G    +  L V++  E+   +Q   ++              
Sbjct: 70  LDLALGDSGQYVCRARNAIGEAFAAVGLQVDA--EAACAEQAPHFL-------------- 113

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE- 444
               L P  ++V       EG    F CRV G P P V+W  + R++ +    ++ V E 
Sbjct: 114 ----LRPTSIRV------REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 445 ---------------SGNHALMITNVTLSDSGVVTCVARNKSGETA-------------F 476
                           G + +   N   + S     V  + + +TA              
Sbjct: 164 GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHL 223

Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536
           Q R   +  E   A        T  V EG+   L+    G P P   W+KDG  +     
Sbjct: 224 QRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR 283

Query: 537 LRIHTDGGAS-TLDIPRAKASDAAWYQCTAQNVAGST 572
             ++ D   +  L I   K SD   Y CTA N+ G T
Sbjct: 284 HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 68/236 (28%), Positives = 104/236 (44%), Gaps = 18/236 (7%)

Query: 1041 QKPRFLGPLKGTN-KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN--RIQTYHD 1097
            Q P FL  L+ T+ ++ EG  A F  RV         V W  +G+++   +  R++    
Sbjct: 108  QAPHFL--LRPTSIRVREGSEATFRCRVGGSP--RPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
                AL I + R  D G Y V A N  G A  +A++ V++ ++   S           H+
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHL 223

Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
            +  +  E M + E    S P      +    V+EGK+  L C +   G+P     W  +G
Sbjct: 224  QRRR--EAM-RAEGAPASPP---STGTRTCTVTEGKHARLSCYVT--GEPKPETVWKKDG 275

Query: 1218 RSVTVGSRFKTYYDF--GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            + VT G R   Y D    FV L I+    +D G YT  A N +G  ++S +V V E
Sbjct: 276  QLVTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 38/130 (29%), Positives = 68/130 (52%), Gaps = 6/130 (4%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V   PRF+ ++   +   EG+ A + C IE  P P +R  WY +G +L +G++++T 
Sbjct: 6101 KILVQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTL 6157

Query: 1897 ND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH-ESALE 1953
            ++   G   L I     ED G Y C+ +N LG A +S  L +QS     ++  H E  + 
Sbjct: 6158 SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVA 6217

Query: 1954 KIQYLEDDSR 1963
             ++  E +++
Sbjct: 6218 AVEVTEQETK 6227



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 17/241 (7%)

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGASTL 548
            AP F+       V++G PV  +    G P P + W KDG  +  +    I+ D  G   L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXX 608
             I     +D   Y+C A+N  G ++T+A L                              
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDT---------AADATESSSY 5235

Query: 609  XXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKI-HFETRIEPVGDPT 667
                 YL   E+        E       PQ +  L+ +    G ++  F+ +++  G P 
Sbjct: 5236 FSAQGYLSSREQEGTESTTDEGQL----PQVVEELRDLQVAPGTRLAKFQLKVK--GYPA 5289

Query: 668  MKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLH 727
             ++ W K+GQ + AS+      +    +L+++S+  +DSG+Y     +A G A + A L 
Sbjct: 5290 PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLL 5349

Query: 728  V 728
            V
Sbjct: 5350 V 5350



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 90/382 (23%), Positives = 154/382 (40%), Gaps = 32/382 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL-KVEWFKNGQPVTIGHRFRPIHDF-GY 1501
            P F+T  ++ E V +G  V F+C    VT   +  V WFK+G+ +     +    D  G 
Sbjct: 5126 PVFLTELQNQE-VQDGYPVSFDCV---VTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST-TDI---VRSTQNEAGLEQIQV 1557
              L I  ++  D G+Y C A N +G       L    T TD      +T++ +       
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 1558 LEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR-AHFERRLIPVSDATLKVEWYHN 1616
            L  R +       DE   Q P     L+++++  G R A F+ ++        ++ W+ +
Sbjct: 5242 LSSREQEGTESTTDE--GQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKD 5297

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY 1676
             +PL + +    T+      L+I+S   EDSG Y     NA+G A +S   +V       
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD--- 5354

Query: 1677 LESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
             E + + A     QL      +R + +      +  F++ ++   V        EA    
Sbjct: 5355 -EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---- 5409

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
                +  V W+    P          H     +L +  V  +  GTYTC A N  G+A+ 
Sbjct: 5410 ----ERGVLWIGPDTPGYTVASSAQQH-----SLVLLDVGRQHQGTYTCIASNAAGQALC 5460

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
            S++L V     ++ + + + AL
Sbjct: 5461 SASLHVSGLPKVEEQEKVKEAL 5482



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 90/366 (24%), Positives = 137/366 (37%), Gaps = 46/366 (12%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PRF+TRPK+   V  G+     C++  V +   +V W K+ QPV  G RFR         
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFR--------- 57

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
                  +A+D  +Y    ++L   D  S +  CR+   I  +     GL+          
Sbjct: 58   ------LAQDGDLYRLTILDLALGD--SGQYVCRARNAIGEAFA-AVGLQ---------- 98

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPL--K 1621
                D       QAP       ++ ++EG  A F  R+         V W  + + L   
Sbjct: 99   ---VDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRV--GGSPRPAVSWSKDGRRLGEP 153

Query: 1622 SGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQH 1681
             G R          AL I +  P D GTY  RA N LG A  +   +V S  +       
Sbjct: 154  DGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPG 213

Query: 1682 EGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPK 1741
                  L  L+     +R + + E    +P  T   +   V E + A     +   G+PK
Sbjct: 214  TSTAALLAHLQ----RRREAMRAEGAPASPPST-GTRTCTVTEGKHARLSCYV--TGEPK 266

Query: 1742 LRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
                W ++G  +    R     D      L + +    D G YTC A N +G+  +S  +
Sbjct: 267  PETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326

Query: 1801 FVQSKA 1806
             V+  A
Sbjct: 327  VVREPA 332



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 63/221 (28%), Positives = 88/221 (39%), Gaps = 13/221 (5%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KTGHRFRPAYEFD 1366
            QAP F     +I   EG+     CR+   G     V W  +G+ +    G R R     +
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426
              AL + +  P D G Y  +A N LG A  S A  ++   D    +  P G      L  
Sbjct: 166  ASALRIRAARPRDGGTYEVRAENPLGAA--SAAAALVVDSDAADTASRP-GTSTAALLAH 222

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
              R ++    + +    P   TR  +   V EG+H    C +    +   +  W K+GQ 
Sbjct: 223  LQRRREAMRAEGAPASPPSTGTRTCT---VTEGKHARLSCYV--TGEPKPETVWKKDGQL 277

Query: 1487 VTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            VT G R     D      L I+     D G+YTC A NLVG
Sbjct: 278  VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 89/404 (22%), Positives = 157/404 (38%), Gaps = 50/404 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            KP +F++++    + E E      E     +P+  W ++   ++ S   Q+     ++ L
Sbjct: 3094 KPSVFSRELTDATITEGEDLTLVCETSTCDIPVC-WTKDGKTLRGSARCQLSHEGHRAQL 3152

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +I    ++DS  +   A   GG   CS+++V    R        P  F    +++ V  G
Sbjct: 3153 LITGATLQDSGRYKCEA---GGA--CSSSIVRVHAR--------PVRFQEALKDLEVLEG 3199

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                L   V  +    V W      ++P  +  + +E     L++    PQDSG+Y C  
Sbjct: 3200 GAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC-- 3256

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
              S G+    A   V+                 P + I  L++K   EG      C++  
Sbjct: 3257 --SFGDQTTSATLTVTA---------------LPAQFIGKLRNKEATEGATATLRCEL-S 3298

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            K  P V+W KG + ++    + + +      L+I      D  +Y CV     G    +A
Sbjct: 3299 KAAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCV----CGEERTSA 3353

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L + +P  A  +  L     I   EG  A  + ++ SK  P ++W +    + +     
Sbjct: 3354 SLTI-RPMPAHFIGRLRHQESI---EGATATLRCEL-SKAAP-VEWRKGRESLRDGDRHS 3407

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +  +G    L I      D G ++C      G+  TSA L VK+
Sbjct: 3408 LRQDGAVCELQICGLAVADAGEYSC----VCGEERTSATLTVKA 3447



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 13/222 (5%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            +PP F +++  C     E  +      G P P+I WY++   ++  P    I        
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI+  +   DS  +   A +  G       ++V+          VPP F    +      
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----------VPPRFVNKVRASPFVE 6121

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLILEAYPQDSGKYE 4585
            G+  +    + G     + W K+G  +    + + L E   G   L+I  A  +D G YE
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            C  +N  G AR  AE  +  P  + + +   +   A  E+ E
Sbjct: 6182 CELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 6223



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 64/236 (27%), Positives = 102/236 (43%), Gaps = 12/236 (5%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTFFN 963
            S   P F T +++Q  +++G    F+  +   G     V W KDG+ +E     +     
Sbjct: 5122 SDAAPVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI---VTKKDIIAESQHPGGLEKI 1020
             G   L I +V   D G Y C A N++G ++T A L +    T  D  A++         
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238

Query: 1021 Q-YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEW 1079
            Q YL  +SR  + TE      Q P+ +  L+        + A F+ +V+        + W
Sbjct: 5239 QGYL--SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYP--APRLYW 5294

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            + +G+ +T++  I+         L+I SV  EDSG Y     NA G A  SA + V
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 62/213 (29%), Positives = 86/213 (40%), Gaps = 14/213 (6%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV--GSRFKTYYDFGFVALDIIHATSAD 1246
            V EG      CR+   G P   V W  +GR +    G R +        AL I  A   D
Sbjct: 121  VREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT 1306
             G Y VRA N LG+A  SA   ++  SD   DT +        LL    RR + +R +  
Sbjct: 179  GGTYEVRAENPLGAA--SAAAALVVDSD-AADTASRPGTSTAALLAHLQRRREAMRAEGA 235

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF- 1365
                P  S         EG +  L C +   G+      W  +G+ +  G R    YE  
Sbjct: 236  PASPP--STGTRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQLVTEGRR-HVVYEDA 290

Query: 1366 -DYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             +   L +L     D G+YTC A+N +G+  +S
Sbjct: 291  QENFVLKILFCKQSDRGLYTCTASNLVGQTYSS 323



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 101/447 (22%), Positives = 171/447 (38%), Gaps = 48/447 (10%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P F T   +  + +     F+C  +        V WF +GK L          D  G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V   D G+Y C A N  G ++   +L+V     +       +   + + S    +
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVD----LTSTDYDTAADATESSSYFSAQ 5239

Query: 3677 ETLHKREEITIED--EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
              L  RE+   E   ++   P+   E++D    P      F  +V+  G P  R+ WF +
Sbjct: 5240 GYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFKD 5297

Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            G+P    + +   +      L+I  +   D+G+Y    +N  G+A ++A++         
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL--------- 5348

Query: 3795 LESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVE 3854
                L +G       E E    SD    E +V  PP+ + +     V++   + F  +VE
Sbjct: 5349 ----LVRGPD-----EPEEKPASDV--HEQLV--PPRMLERFTPKKVKKGSSITFSVKVE 5395

Query: 3855 PKEDPKLRIEWYR----NGKLL--PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
             +  P   + W R     G L   P    Y         SL +L V  +  G Y C A N
Sbjct: 5396 GRPVP--TVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASN 5453

Query: 3909 DFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTED--DLYD 3966
              G+    A++    LP +  Q +V    K +   T ++ T +  +++   T    DL  
Sbjct: 5454 AAGQALCSASLHVSGLPKVEEQEKV----KEALISTFLQGTTQAISAQGLETASFADL-G 5508

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKF 3993
              +K+ P    +     SL E+ T +F
Sbjct: 5509 GQRKEEPLAAKEALGHLSLAEVGTEEF 5535



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 73/324 (22%), Positives = 126/324 (38%), Gaps = 29/324 (8%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P   + W+ +GK+LE+   + +  D  G   L +  V   D G+Y C A N  G + T +
Sbjct: 5153 PMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKA 5212

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD 3059
             +         +       +      Q    S R++ G +   D G+ P+     +D+  
Sbjct: 5213 ELRVDLTSTDYDTAADATESSSYFSAQGYLSS-REQEGTESTTDEGQLPQVVEELRDLQV 5271

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
                ++A ++  +   G  +  + WF +G+ + AS  IR      +  LEI+     DSG
Sbjct: 5272 APGTRLAKFQLKV--KGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSG 5329

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNI----------EGLKDGQSAH 3168
             Y+   +N  G A  S +L      +  +KP    H Q +          + +K G S  
Sbjct: 5330 QYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSIT 5389

Query: 3169 FECTV----VPV-----DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
            F   V    VP      ++ +  + W   G      T   +      V+LD+   + H  
Sbjct: 5390 FSVKVEGRPVPTVHWLREEAERGVLWI--GPDTPGYTVASSAQQHSLVLLDVG--RQH-Q 5444

Query: 3220 GEYVCRAYNKYGEDFTRATINCYG 3243
            G Y C A N  G+    A+++  G
Sbjct: 5445 GTYTCIASNAAGQALCSASLHVSG 5468



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 82/373 (21%), Positives = 150/373 (40%), Gaps = 54/373 (14%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W + +  +++   + +    TK  L IR + + D+  ++ V     G  + SA L V 
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVC----GQERTSAMLTVR 3622

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
                      +P  FT   +N   T G    L  +++   P++  W K  + ++   R+ 
Sbjct: 3623 A---------LPIKFTEGLRNEEATEGATAVLRCELSKMAPVE--WWKGHETLRDGDRHS 3671

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            + ++     L I     +D+G+Y C+     G+ R  A   V                  
Sbjct: 3672 LRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRA---------------M 3712

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P + IE L+++   EG      C++  K  P V+W KG + ++      + +      L+
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCEL-SKAAP-VEWRKGHETLRDGDRHSLRQDGSRCELQ 3770

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQ 4739
            I      D G+Y CV     G+   +A L V        LPA  +  +++    EG  A 
Sbjct: 3771 IRGLAVVDAGEYSCV----CGQERTSATLTVRA------LPARFIEDVKNQEAREGATAV 3820

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
             + ++ SK  P ++W +    +     + +  +G    L I      DTG ++C      
Sbjct: 3821 LQCEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC----VC 3874

Query: 4800 GQVETSAKLVVKS 4812
            GQ  TSA L V++
Sbjct: 3875 GQERTSATLTVRA 3887



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 6/133 (4%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD- 3883
            +V  PP+F+ ++++    E E  +F C +E    P++R  WY++G LL +G++++T+ + 
Sbjct: 6103 LVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 6160

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR-GMKRSE 3941
              G + L I     ED G Y C  VN  G     A +  +  P +  Q Q  R  +  + 
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS-PMLQAQEQCHREQLVAAV 6219

Query: 3942 ALTQMEATIKKYT 3954
             +T+ E  + K T
Sbjct: 6220 EVTEQETKVPKKT 6232



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 3/122 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
            PP+   K R S   EG DAQF   + G P P++ W+K+G  L   NK + ++        
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 6166

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP-TESYVQDQRSQYITDTQQRETEE 381
            L +R   K D G Y     N  G    S  L ++SP  ++  Q  R Q +   +  E E 
Sbjct: 6167 LVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQET 6226

Query: 382  RI 383
            ++
Sbjct: 6227 KV 6228



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 61/238 (25%), Positives = 105/238 (44%), Gaps = 15/238 (6%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GF 3477
            APVF   L N E +++G    F+  +T    P+  V W+ +GK L+    +    D  G 
Sbjct: 5125 APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPS--VRWFKDGKLLEEDDHYMINEDQQGG 5181

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIA 3536
              L I+   P D G Y C A N+ G + T A ++V      +  +      + T      
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-----LTSTDYDTAADATESSSYF 5236

Query: 3537 ALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSS-AHFECRLIPVNDSSMRVEW 3593
            + +GY  + +    E+  + G  P+      DL ++  +  A F+ ++      + R+ W
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYW 5294

Query: 3594 FHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            F +G+PL   + ++  +      LEI  V + D+G Y    +N  G A  S +L V+G
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 58/219 (26%), Positives = 95/219 (43%), Gaps = 16/219 (7%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            + V + P  FSR L ++ T E   V LEC L       + V W  +G  ++ G     A 
Sbjct: 2159 LVVTELPVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAA 2215

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK-DLILESQHPSGLEKIQ 1422
            +    +L +      D GVY C A     +A +S +++V  +   LI          +IQ
Sbjct: 2216 QGACRSLTIYRCEFADQGVYVCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQ 2271

Query: 1423 YLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK 1482
            ++ + +  +    + E     P  + RP   +  +E      EC+   V+ ++ +V WFK
Sbjct: 2272 FVAENAESRAQLRVKEL----PVTLVRPLRDKIAMEKHRGVLECQ---VSRASAQVRWFK 2324

Query: 1483 NGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
              Q +  G ++  + D  Y  L I D+ AED   YTC A
Sbjct: 2325 GSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 63/255 (24%), Positives = 108/255 (42%), Gaps = 28/255 (10%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            V WLK+G +++   R++   +  T+TL +  A   DS  Y C         R  AE    
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC---------RVGAE---- 1796

Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
                +D P    + A     ++EP+  ++   G  +  +C++       V W  G+  ++
Sbjct: 1797 ---GQDFPVQVEEVAAKFCRLLEPVCGEL---GGTVTLACEL-SPACAEVVWRCGNTQLR 1849

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
              K FQM       +L +     ED G+Y C + +       +A+L V+ P     +  +
Sbjct: 1850 VGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDD----HTSAQLTVSVPRV---VKFM 1902

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
            + L  +V  EG  A F+  + S     + W R+GAL+  +  F +   G +  L I +  
Sbjct: 1903 SGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLV 1961

Query: 4785 EEDTGTFTCRATTAA 4799
             ED G  T  A  A+
Sbjct: 1962 LEDAGQITVEAEGAS 1976



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 50/203 (24%), Positives = 86/203 (42%), Gaps = 12/203 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            E + V LE ++   + PN+ + W K+GV L  G  +         +L+I      D G+Y
Sbjct: 2179 EKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVY 2235

Query: 2716 TCKATNLLGEAVSTASIKIEDRHW-LLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXX 2774
             C A     +A S+AS+K++ R + L+   +  +    I  +                  
Sbjct: 2236 VCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVT 2291

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            + +  L + +  E      EC V  +   + ++ WF  ++ L  G +Y+   D  Y  L 
Sbjct: 2292 L-VRPLRDKIAMEKHRGVLECQVSRA---SAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347

Query: 2835 ITHTYEEDSGIYTCKATNSKGSA 2857
            I+  + ED   YTC A + K SA
Sbjct: 2348 ISDVHAEDEDTYTCDAGDVKTSA 2370



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 59/261 (22%), Positives = 108/261 (41%), Gaps = 29/261 (11%)

Query: 1700 HSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            H++   V+T+ PV F+ P++D+   E +    E  L     P + V WL++GV + A   
Sbjct: 2154 HTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKT 2210

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            +         +L +      D G Y C A +             QS AS++++ +  + +
Sbjct: 2211 MAIAAQGACRSLTIYRCEFADQGVYVCDAHD------------AQSSASVKVQGRTYTLI 2258

Query: 1819 QKIQQLEDSSRYQ-----RREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPD 1873
             +    ED+   Q          ++ V + P  + +        E      EC++     
Sbjct: 2259 YRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSR--- 2315

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             + +V W+   + LQ G +Y   +D  +  L I  V+ ED   YTC A    G   +S +
Sbjct: 2316 ASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQ 2371

Query: 1934 LNVQSKE-SIIRDSQHESALE 1953
              V+ +  +I+R  Q  + +E
Sbjct: 2372 FFVEEQSITIVRGLQDVTVME 2392



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 49/180 (27%), Positives = 78/180 (43%), Gaps = 15/180 (8%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            QD + TE     F C ++     EV W +N   + +D  H+I  ++   H L++ ++  +
Sbjct: 2565 QDAEATEEGWASFSCELSHED-EEVEWSLNGMPLYNDSFHEIS-HKGRRHTLVLKSIQRA 2622

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G+V    R  S + +   RL V  K  V    F++    L+  E   + L    V  P
Sbjct: 2623 DAGIV----RASSLKVSTSARLEVRVKPVV----FLKALDDLSAEERGTLALQCE-VSDP 2673

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               + W+KDGV + P+ +       G   L +      DA  Y C      GS  TRAR+
Sbjct: 2674 EAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARV 2729



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 60/234 (25%), Positives = 95/234 (40%), Gaps = 8/234 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIV 3340
            P F+T++Q+  ++ +G    F+   V    P   V WF +GK L     Y    D  G  
Sbjct: 5126 PVFLTELQN-QEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400
             L I      + G Y C+A N +G  STKA L+     +   D+             Q  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELR-VDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
              S   ++ T    ++G+ P     L +++       A F+ ++     P L   W+ +G
Sbjct: 5242 LSSR-EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRL--YWFKDG 5298

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            + L A +  R         LEI     EDSG+Y     N  G A ++A + V+G
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 65/284 (22%), Positives = 116/284 (40%), Gaps = 28/284 (9%)

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            ++ V   +G    L  +V   +  +V W K+GKK+    + ++     T  L++ EA   
Sbjct: 1541 SREVQAEAGTSATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQA 1599

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQ 4638
            D+G+Y C     AG+ R      V+ P          K   A  +   P   ++ AE G 
Sbjct: 1600 DAGEYSC----KAGDQRLSFHLHVAEP----------KVVFAKEQ---PAHREVQAEAGA 1642

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            +   SC+ V +    V WYK  K +  S   ++        L + +A   + G+Y C   
Sbjct: 1643 SATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSC--- 1698

Query: 4699 NSAGRVTVAAKLKVTQPD-QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
              AG   ++ +L+V + + Q    P       +VV E +       + +    T+ WL++
Sbjct: 1699 -EAGGQQLSFRLQVAELEPQISERPCRR--EPLVVKEHEDIILTATLATPSAATVTWLKD 1755

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
            G  I  +   +   +G+   L +      D+  ++CR   A GQ
Sbjct: 1756 GVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCR-VGAEGQ 1798



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 101/402 (25%), Positives = 157/402 (39%), Gaps = 48/402 (11%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLP-LIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            TK+++   V E E   FE     E       W      + +S  FQ      K IL++R+
Sbjct: 2739 TKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVRE 2798

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
                D+     V   RG T+K  A+L+V E+       I+ P   L  Q V       +R
Sbjct: 2799 AAPSDAG--EVVFSVRGLTSK--ASLIVRERP----AAIIKP---LEDQWVAPGEDVELR 2847

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
             +    GT    V+WLK+ K ++   +  ++ E GT  +L++             ++  A
Sbjct: 2848 CELSRAGTP---VHWLKDRKAIRKSQKYDVVCE-GTMAMLVIRG----------ASLKDA 2893

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
            GE  C+ E   S  +   + K     AN   E +  L+  +  +G A+ F+CK    P  
Sbjct: 2894 GEYTCEVEASKSTASLHVEEK-----ANCFTEELTNLQ--VEEKGTAV-FTCK-TEHPAA 2944

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            TV W KG   ++ S   Q S+      L IS     D   Y C      G+    A+L V
Sbjct: 2945 TVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLV 3000

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM-IH 4771
                Q   +  +  L D+ V EG  A F+ +I+      + W  +   +      ++   
Sbjct: 3001 ----QGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQ 3056

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             G   VL +     +D+GT        AG    SA L V  K
Sbjct: 3057 PGGYHVLTLRQLALKDSGTIYFE----AGDQRASAALRVTEK 3094



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 49/189 (25%), Positives = 77/189 (40%), Gaps = 14/189 (7%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS-HRIRTVYAFG 3104
            RPP+F    +++ D +       + +   TG    VI W+ +GK ++   H I      G
Sbjct: 6012 RPPDFE---EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG 6068

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +      DSG Y C A +  G      K+          PRF   ++      +G
Sbjct: 6069 SCALILDSLTGVDSGQYMCFAASAAGNCSTLGKI-----LVQVPPRFVNKVR-ASPFVEG 6122

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEY 3222
            + A F CT+     P  +I WY +G  +    + +T+S+   G +VL I      D G Y
Sbjct: 6123 EDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 6180

Query: 3223 VCRAYNKYG 3231
             C   N+ G
Sbjct: 6181 ECELVNRLG 6189



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 78/361 (21%), Positives = 140/361 (38%), Gaps = 38/361 (10%)

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
            +P   + WY++   + +S   ++        L+++QV   D+  ++  A    G  + S 
Sbjct: 1192 QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSF 1247

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             L + E +       V     L    V   +G    L  +V   +  +V W K+GKK+  
Sbjct: 1248 QLHITEPKA------VFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSS 1300

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
              + +I        L++ +A   D+G+Y C     AG  R      VS P          
Sbjct: 1301 SSKVRIEAAGCMRQLVVQQAGQADAGEYTC----EAGGQRLSFHLDVSEP---------- 1346

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIE-FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675
            KA  A  ++      K+ AE  AI   SC+ V +    V WYK  K +  S   +M    
Sbjct: 1347 KAVFAKEQLAHR---KVQAEAGAIATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRMEAVG 1402

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RDIVVYE 4734
                L + +A   D G+Y C     AG   ++  L V +P          P+ R++    
Sbjct: 1403 CTRRLVVQQACQADTGEYSC----EAGGQRLSFSLDVAEPKVV--FAKEQPVHREVQAQA 1456

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G       ++ ++ +  + W ++G  +  +   +M   G    L++    +   G ++C 
Sbjct: 1457 GASTTLSCEV-AQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCE 1515

Query: 4795 A 4795
            A
Sbjct: 1516 A 1516



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 76/357 (21%), Positives = 142/357 (39%), Gaps = 40/357 (11%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S   ++        L+++Q    D+  ++  A    G  + S +L V 
Sbjct: 1381 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVA 1436

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E +      +V        + V   +G    L  +V   +  +V W K+GKK+    + +
Sbjct: 1437 EPK------VVFAKEQPVHREVQAQAGASTTLSCEVAQAQT-EVMWYKDGKKLSFSSKVR 1489

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +     T  L++ +A    +G+Y C     AG  R      V+ P          KA  A
Sbjct: 1490 MEAVGCTRRLVVQQAGQAVAGEYSC----EAGSQRLSFHLHVAEP----------KAVFA 1535

Query: 4622 PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
              +   P   ++ AE G +   SC+ V +    V WYK  K +  S   +M        L
Sbjct: 1536 KEQ---PASREVQAEAGTSATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRL 1591

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ--ADNLPALTPLRDIVVYEGQPA 4738
             + EA   D G+Y C     AG   ++  L V +P    A   PA    R++    G  A
Sbjct: 1592 VVQEAGQADAGEYSC----KAGDQRLSFHLHVAEPKVVFAKEQPA---HREVQAEAGASA 1644

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
                ++ ++ +  + W ++G  +  +   ++   G    L++    + + G ++C A
Sbjct: 1645 TLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEA 1700



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 59/230 (25%), Positives = 95/230 (41%), Gaps = 8/230 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFV 2566
            P+F   L    E+ +G    ++  V     PS+R  W+ +G  L+    +    D  G  
Sbjct: 5126 PVFLTELQN-QEVQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAM-RPESWEQIQLKEAA 2625
             L I +VV  D G+Y C A N  G                 D A    ES      +   
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 2626 MNKVPEMFVDTGVQ-QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684
             ++  E    T  + Q P     L+   ++  G  +  + Q++ +  P  ++ WFK+G  
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDL-QVAPGTRL-AKFQLKVKGYPAPRLYWFKDGQP 5300

Query: 2685 LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            LT  A ++ T    L TL I S+  +DSG Y    +N +G A S+A + +
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 53/211 (25%), Positives = 88/211 (41%), Gaps = 10/211 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYV 4031
            P F+T++Q+Q  + +     F+C +   G P   V WF +GK L   + +    D  G  
Sbjct: 5126 PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE-- 4089
             +    V P D G Y C A N  G+  TKA ++        YD+       S     +  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-LTSTDYDTAADATESSSYFSAQGY 5241

Query: 4090 MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            + +  Q   E   +E +   P V   L D         A+F  +V G+P PR+ W  +G 
Sbjct: 5242 LSSREQEGTESTTDEGQL--PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQ 5299

Query: 4150 TIVNGSRYKLTYDGMYH-FDIPKTRQYDTGK 4179
             +   +  ++T   + H  +I    + D+G+
Sbjct: 5300 PLTASAHIRMTDKKILHTLEIISVTREDSGQ 5330



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+F           G +  L C++  VG+ T +V W  + +P+  G RFR A + D   
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
            L +L +   DSG Y C+A N +GEA  +  L+V A+     ++ H
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 64/252 (25%), Positives = 101/252 (40%), Gaps = 21/252 (8%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F+ PL ++    E E    E  L+    PN+ V W  +G  L+AG             L 
Sbjct: 2168 FSRPLQDVVTT-EKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGY 3541
            I      D G Y+C A+    +A ++AS+KVQG+   ++  ++     G I  +A  E  
Sbjct: 2224 IYRCEFADQGVYVCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVA--ENA 2277

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
                     E     P        D I  E      EC+   V+ +S +V WF   + L 
Sbjct: 2278 ESRAQLRVKEL----PVTLVRPLRDKIAMEKHRGVLECQ---VSRASAQVRWFKGSQELQ 2330

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ----VKGRQGIIL 3657
             G + + ++D  +  L I  V+  D   YTC A +    A    + Q    V+G Q + +
Sbjct: 2331 PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTV 2390

Query: 3658 EPQLPSHFKSGT 3669
                P+ F+  T
Sbjct: 2391 MEPAPAWFECET 2402



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 33/106 (31%), Positives = 57/106 (53%), Gaps = 3/106 (2%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            APRF+T+      +S G+ A   C+I   P P  +V W  + + + +G R+R + D    
Sbjct: 9    APRFLTRPKAFV-VSVGKDATLSCQIVGNPTP--QVSWEKDQQPVAAGARFRLAQDGDLY 65

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
             L IL +   DSG+Y C+A N +G+A +++ L V ++ +    + H
Sbjct: 66   RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 72/355 (20%), Positives = 139/355 (39%), Gaps = 36/355 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S    +     +  L+++Q    D+  ++   E RG       + + E
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC--EARGQRVSFRLH-ITE 1069

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
             K    +   V       A    + S ++ +  T+VT        W K+GKK+    +  
Sbjct: 1070 PKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVT--------WYKDGKKLSSSSKVG 1121

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +  +  T  L++ +A   D+G+Y C     AG  R      ++ P          K   A
Sbjct: 1122 MEVKGCTRRLVLPQAGKADAGEYSC----EAGGQRVSFHLHITEP----------KGVFA 1167

Query: 4622 PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
              + +    +++ AE G     SC+ V +P   V WYK  K +  S   +M        L
Sbjct: 1168 KEQSVH---NEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRL 1223

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             + +    D G+Y C     AG   V+ +L +T+P        L    ++    G  A  
Sbjct: 1224 VVQQVGKADAGEYSC----EAGGQRVSFQLHITEPKAVFAKEQLVH-NEVRTEAGASATL 1278

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
              ++ ++ +  + W ++G  +  +   ++   G    L++    + D G +TC A
Sbjct: 1279 SCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 143/711 (20%), Positives = 251/711 (35%), Gaps = 54/711 (7%)

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLT 4160
            E + A   P F+  P ++ V EG  A F CRV G P+P V W  +G  +   +G R ++ 
Sbjct: 102  EAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVE 161

Query: 4161 YDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR---GVLKNAPRP 4216
              G      I   R  D G  EV              L V     D     G    A   
Sbjct: 162  ELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLA 221

Query: 4217 WYDETTQYQRTE--TELEKTFEERQVLQRQGVIDHRPELKPKVIKEP--ETEWQQSVKRK 4272
                  +  R E       +   R     +G       L   V  EP  ET W++  +  
Sbjct: 222  HLQRRREAMRAEGAPASPPSTGTRTCTVTEG---KHARLSCYVTGEPKPETVWKKDGQLV 278

Query: 4273 KNEEYYNKLQELENEQVIKESRLRESTH-QYAIPGDKVTSNTVAKSMAQRYEDNLDQTEE 4331
                 +   ++ +   V+K    ++S    Y      +   T +  +    E  +   + 
Sbjct: 279  TEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKR 338

Query: 4332 VTEQRVQKK--VTQKPRIPDPS-ESTVHGKEVHV-AKQKQTQKEVVGDKEITRKITSTET 4387
            + +  V++K   T    +P PS E+    +E  + A  K   +E   ++ +T +  S + 
Sbjct: 339  LQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADD 398

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
              + +  +T E          +  +  K  +   V   + A F VE    P+  + W R 
Sbjct: 399  DAV-YICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVEL-AVPVGPVHWLRN 456

Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
               +       I    T+  L I Q  +ED    A +A    G  + S    V   R+  
Sbjct: 457  QEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMA----GDCQTSTQFCVSAPRKP- 511

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP--IDVYWLKNGK-KVQPDIRNKILE 4564
               + PP   +      + S  ++       G +P  ID Y ++  K      IR    E
Sbjct: 512  --PLQPPVDPVV--KARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAE 567

Query: 4565 EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD-KPKPQTKAANAPP 4623
               T  L + +   + + ++   A+NS G++       +  P T    PK   +      
Sbjct: 568  WVATPELTVADVAEEGNFQFRVSALNSFGQSP-----YLEFPGTVHLAPKLAVRT----- 617

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
                PLK     EG  + FS  +        +W+   + +K S  +++      +TL I 
Sbjct: 618  ----PLKAVQAVEGGEVTFSVDLT--VASAGEWFLDGQALKASSVYEIHCDRTRHTLTIR 671

Query: 4684 EAFPEDEG-DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
            E      G   K VA      + +  +     P    N P     R+++    + AQ   
Sbjct: 672  EVPASLHGAQLKFVANGIESSIRMEVR---AAPGLTANKPPAAAAREVLARLHEEAQLLA 728

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +++ +    + WL++G  +   P +++       VLL+ +   +D G + C
Sbjct: 729  ELSDQ-AAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 69/275 (25%), Positives = 110/275 (40%), Gaps = 25/275 (9%)

Query: 1974 VVEKP-QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P  F +P+++   TE   V LE  L+    P + V W  +G  ++ G         
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQG 2217

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG--LYLDTLDEQRLKKIQE 2090
               +L I      D G Y+C A +A   A    SVKV  ++   +Y   L E    +IQ 
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDAQSSA----SVKVQGRTYTLIYRRVLAEDA-GEIQF 2272

Query: 2091 LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQ 2150
            +   E  +   + +  + PV L      +   E  R   EC+V   +     + WF   Q
Sbjct: 2273 VA--ENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRAS---AQVRWFKGSQ 2327

Query: 2151 KIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILD 2210
            +++ G +Y    D  Y  L I   +AED  TY C A +     V T        ++I + 
Sbjct: 2328 ELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD-----VKTSAQFFVEEQSITI- 2381

Query: 2211 TQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV 2245
                 GL+ +  +E        E   P + PP+++
Sbjct: 2382 ---VRGLQDVTVMEPAPAWFECETSIPSVRPPKWL 2413



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 5/115 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            VQ  P F   +++    VEG+       +E    P  +I W+K+G  LTTG + ++  + 
Sbjct: 6104 VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEP 6160

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
              GL+ L I +   +D G+Y C+  N LG A ++A ++I+       E  H + L
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL 6215



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 4/128 (3%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
            ++P  S  P+F+T+ K+  V   +     C++     P+  + W ++ + + +G R+R  
Sbjct: 2    DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQ--VSWEKDQQPVAAGARFRLA 59

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSE 3941
             D     L IL +   DSG+Y+CRA N  GE F  A +  +   +     Q P  + R  
Sbjct: 60   QDGDLYRLTILDLALGDSGQYVCRARNAIGEAF--AAVGLQVDAEAACAEQAPHFLLRPT 117

Query: 3942 ALTQMEAT 3949
            ++   E +
Sbjct: 118  SIRVREGS 125



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 91/404 (22%), Positives = 155/404 (38%), Gaps = 48/404 (11%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFV 3207
            P F T +QN E ++DG    F+C V     P   + W+ +G+ +          D  G  
Sbjct: 5126 PVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQ 3267
             L I      D G Y C A N  G   T+A +       V L S   D+ A   E  S  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELR------VDLTSTDYDTAADATESSSYF 5236

Query: 3268 GAQQQTPS---------TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEW 3318
             AQ    S         T   + P+ + +++D+      + A F+ ++     P  ++ W
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYW 5294

Query: 3319 FYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            F +G+ L      R      +  L+I+    E+SG+Y    +N +G   + A L      
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL------ 5348

Query: 3379 NLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENA 3438
             L+     P          Q +   M+ R  T  + +KG +  F+V +      R     
Sbjct: 5349 -LVRGPDEPEEKPASDVHEQLVPPRMLER-FTPKKVKKGSSITFSVKVEG----RPVPTV 5402

Query: 3439 HFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAY 3498
            H+   L    +  +     W G      +   +      V+L++     +  G Y C A 
Sbjct: 5403 HW---LREEAERGV----LWIGPDTPGYTVASSAQQHSLVLLDVG---RQHQGTYTCIAS 5452

Query: 3499 NNYGEAVTTASMKVQG-----KRNIILESQLPKGMEGTIDKIAA 3537
            N  G+A+ +AS+ V G     ++  + E+ +   ++GT   I+A
Sbjct: 5453 NAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISA 5496



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 10/146 (6%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FGF 1234
            P FV  +   P V EG++    C +E  G P  ++ W+ +G  +T G++F+T  +   G 
Sbjct: 6108 PRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQLLED 1293
            + L I  A+  D G Y    VN LGSA  SA +R+             EQ +  +++ E 
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQ 6224

Query: 1294 ---AARRTKQVREDI-TVMQAPQFSR 1315
                 ++T  + E I TV+++P+  R
Sbjct: 6225 ETKVPKKTVIIEETITTVVKSPRGQR 6250



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 51/241 (21%), Positives = 103/241 (42%), Gaps = 24/241 (9%)

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            R  NTQ      + ++AE P   +   G  A ++           +Y+ +++   T  ++
Sbjct: 1842 RCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDA----------GEYVCESRDDHTSAQL 1891

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
             +S   +  +F+         EG    F C V+      V WF +   ++   + K  ++
Sbjct: 1892 TVSVPRVV-KFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQP--SEKFAIS 1947

Query: 444  ESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +SG +H+L I+++ L D+G +T  A   S   A + R   +  ++ + P+ VE  S++ +
Sbjct: 1948 QSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTL 2007

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             E E        +  P P + W ++   + P   + IH +G    L +     +D  ++ 
Sbjct: 2008 -EVE--------LTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFG 2058

Query: 563  C 563
            C
Sbjct: 2059 C 2059



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 36/138 (26%), Positives = 65/138 (47%), Gaps = 6/138 (4%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD- 1498
            V + PRFV + ++    +EG+   F C +E      ++  W+K+G  +T G++F+ + + 
Sbjct: 6104 VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 6160

Query: 1499 -FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLEQIQ 1556
              G + L I     ED G+Y C  VN +G+   S  L  +S           E  +  ++
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVE 6220

Query: 1557 VLEDRSKYHRTDMVDEVT 1574
            V E  +K  +  ++ E T
Sbjct: 6221 VTEQETKVPKKTVIIEET 6238



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 69/302 (22%), Positives = 120/302 (39%), Gaps = 39/302 (12%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT- 4570
            +P  FT   +N     G    L  +++   P++  W K  + ++   R  IL ++GT   
Sbjct: 3448 LPAKFTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCE 3504

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L I      D+G+Y CV     G+ R  A   +                  P   IE +K
Sbjct: 3505 LQICGLAMADAGEYLCVC----GQERTSATLTIRA---------------LPARFIEDVK 3545

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
            ++   EG      C++       V+W KG + ++    + + +   +  L+I      D 
Sbjct: 3546 NQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADT 3603

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G+Y CV     G+   +A L V    +A  +     LR+    EG  A  + ++ SK+ P
Sbjct: 3604 GEYSCV----CGQERTSAMLTV----RALPIKFTEGLRNEEATEGATAVLRCEL-SKMAP 3654

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             ++W +    + +     +  +G    L I     ED G + C      G+  TSA L V
Sbjct: 3655 -VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLC----MCGKERTSAMLTV 3709

Query: 4811 KS 4812
            ++
Sbjct: 3710 RA 3711



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 27/70 (38%), Positives = 40/70 (57%)

Query: 2004 VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            V +PT +V W  + +PV  G RF+   D     L IL     D+G Y+C+A NA+GEA  
Sbjct: 34   VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFA 93

Query: 2064 TSSVKVDAKS 2073
               ++VDA++
Sbjct: 94   AVGLQVDAEA 103



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 40/141 (28%), Positives = 67/141 (47%), Gaps = 6/141 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V   P+F   +     VEG +    C ++  G    ++ W+ +G  + TG++F+   E
Sbjct: 6102 ILVQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 1365 --FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL-EKI 1421
                 + L + +   ED G+Y C+  N+LG A  S  LR+ +      E  H   L   +
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAV 6219

Query: 1422 QYLE-DTSRYKKTDIIDESVT 1441
            +  E +T   KKT II+E++T
Sbjct: 6220 EVTEQETKVPKKTVIIEETIT 6240



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 4/78 (5%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEY 144
           G +A    ++ GNPTP VSW + + P+    ++ +    Q GD+  L I  +  GD G+Y
Sbjct: 24  GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA---QDGDLYRLTILDLALGDSGQY 80

Query: 145 TCTARNQYGEAICSVYIQ 162
            C ARN  GEA  +V +Q
Sbjct: 81  VCRARNAIGEAFAAVGLQ 98



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 40/164 (24%), Positives = 66/164 (40%), Gaps = 7/164 (4%)

Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           D   G   +F+C  T   +  V W+ +  ++       +  +    H L+   VT  D G
Sbjct: 808 DAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEG 866

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
             +C    + GE +   RL V E + V A + + R   L    G    L+       T  
Sbjct: 867 TYSC----RVGEDSVDFRLRVSEPKVVFAKEQLAR-RKLQAEAGASATLSCEVAQAQT-E 920

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           +TW KDG  +  + ++ +   G    L + +A  +DA  Y C A
Sbjct: 921 VTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 79/378 (20%), Positives = 148/378 (39%), Gaps = 33/378 (8%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GL 2699
            AP+F T L++ + + +G  V  +  V  +  P+++  WFK+G  L          D  G 
Sbjct: 5125 APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGG 5181

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE----DRHWLLGESLHPDSLDRIGA 2755
              L I ++   D G+Y C A N +G + + A ++++    D       +         G 
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 2756 LXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI-HFECNVEPSRDPTLKIEWFFNNK 2814
            L                    +  L ++    G  +  F+  V+    P  ++ WF + +
Sbjct: 5242 LSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGY--PAPRLYWFKDGQ 5299

Query: 2815 PLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFD 2874
            PL +    + T      +L+I     EDSG Y    +N+ G+A +S  L   G       
Sbjct: 5300 PLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG------- 5352

Query: 2875 TQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQ 2934
               P+ K   +  EQ    R+ +   P     +  K    I  + +   VEG+ +     
Sbjct: 5353 PDEPEEKPASDVHEQLVPPRMLERFTP-----KKVKKGSSITFSVK---VEGRPVPTVHW 5404

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            +  + + +  + W     +      + + S     +L L+DV  +  G YTC A N  G+
Sbjct: 5405 L--REEAERGVLW-----IGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457

Query: 2995 AFTSSTVYCTSKDNLIER 3012
            A  S++++ +    + E+
Sbjct: 5458 ALCSASLHVSGLPKVEEQ 5475



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 42/159 (26%), Positives = 68/159 (42%), Gaps = 9/159 (5%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +   EVTW+ + +++    + K+ V   G    L++     +++G  +
Sbjct: 1641 GASATLSCEVA-QAQTEVTWYKDGKKLSS--SSKVRVEAVGCTRRLVVQQAGQAEAGEYS 1697

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A    G      RL V E E  ++ +   R   L V+E E ++L A         +TW
Sbjct: 1698 CEA----GGQQLSFRLQVAELEPQISERPCRR-EPLVVKEHEDIILTATLATPSAATVTW 1752

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             KDGV I  +      + G   TL +  A+  D+A Y C
Sbjct: 1753 LKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC 1791



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 83/425 (19%), Positives = 158/425 (37%), Gaps = 53/425 (12%)

Query: 4380 RKITSTETTEIEH---KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            R+  ST T  +     K+++  R+V   +    P + T+ ++P    E +      +F  
Sbjct: 2439 RRTCSTMTGPVHFTVGKSRSSARLVVSDI----PVVLTRPLEPKTGRELQSVVLSCDFRP 2494

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
             P   ++WY+++ P+  S  F++      + L I ++   D+ V+   A    G+A  S 
Sbjct: 2495 AP-KAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSST 2549

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             + VE +     G +         Q+   T         +++  +  +V W  NG  +  
Sbjct: 2550 EVTVEAREVTVTGPL---------QDAEATEEGWASFSCELS-HEDEEVEWSLNGMPLYN 2599

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
            D  ++I  +   +TL++      D+G     ++  +  AR +                  
Sbjct: 2600 DSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVRV--------------- 2644

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
                 P   ++ L D    E   +   C+ V  P   V W K    + PS  +    TA 
Sbjct: 2645 ----KPVVFLKALDDLSAEERGTLALQCE-VSDPEAHVVWRKDGVQLGPSDKYDFLHTAG 2699

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L + +  PED G Y C      G     A+++V       ++     L+ + V EG+
Sbjct: 2700 TRGLVVHDVSPEDAGLYTC----HVGSEETRARVRVHDL----HVGITKRLKTMEVLEGE 2751

Query: 4737 PAQFKTQIT-SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG--TFTC 4793
               F+  ++         W   G  +  +  FQ   +G   +L++      D G   F+ 
Sbjct: 2752 SCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSV 2811

Query: 4794 RATTA 4798
            R  T+
Sbjct: 2812 RGLTS 2816



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 37/136 (27%), Positives = 64/136 (47%), Gaps = 8/136 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND--FGF 3614
            PP F          E   A F C +       +R  W+ +G  L TG++ +T+++   G 
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
            ++L I    + D GLY C+  NR G A  S +L++   Q  +L+ Q   H +    +++ 
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLVAAVEV 6221

Query: 3675 LE-ETLHKREEITIED 3689
             E ET   ++ + IE+
Sbjct: 6222 TEQETKVPKKTVIIEE 6237



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            P+ +  P F T  K  + +  G  A    ++  +G+ T +V W KD +PV A +R     
Sbjct: 4    PQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQ 60

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            +     LTI  + + D+G Y CRA NAIG+A  +  L +  +     ++ H
Sbjct: 61   DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 111/485 (22%), Positives = 188/485 (38%), Gaps = 51/485 (10%)

Query: 922  KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
            +EGG A F+  + P   S + V W +DG  ++ S +     +    +LTI  + + DAG 
Sbjct: 1911 EEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ 1967

Query: 982  YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
             T  A  A    ++SA L +     +  +   P  +E+   +      + R   E++ T+
Sbjct: 1968 ITVEAEGA----SSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTR 2022

Query: 1042 KPRFLGPLKGTNKIVEG-------QSAHFEAR----VEPQSDLT---MTVEWYFNGKQIT 1087
                L P K      EG        +  F  R     E   D T   +TVE     +Q+ 
Sbjct: 2023 NATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM----RQVR 2078

Query: 1088 SANRIQTYH--DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSS 1145
                +Q     + G   +++    A+  G +T   R+     Q   +  +  R  + T +
Sbjct: 2079 LVRGLQAVEAREQGTATMEVQLSHADVDGSWT---RDGL-RFQQGPTCHLAVRGPMHTLT 2134

Query: 1146 IHRGLYEKTRHIEESKFVEPMYQIEEISKSKPV-FVQPLSNPPPVSEGKNIHLECRLEPM 1204
            +  GL  +   +   K          +    PV F +PL +    +E + + LEC L   
Sbjct: 2135 LS-GLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVV-TTEKEKVTLECELSR- 2191

Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264
              P + V W  +G  +  G            +L I     AD G Y   A  H   A +S
Sbjct: 2192 --PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDA--H--DAQSS 2245

Query: 1265 AIVRVIERS-DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP-QFSRALHNIET 1322
            A V+V  R+  ++      +   +IQ + + A    Q+R    V + P    R L +   
Sbjct: 2246 ASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLR----VKELPVTLVRPLRDKIA 2301

Query: 1323 VEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGV 1382
            +E     LEC+   V   + +V WF   + ++ G ++    +  Y  L +  V+ ED   
Sbjct: 2302 MEKHRGVLECQ---VSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDT 2358

Query: 1383 YTCQA 1387
            YTC A
Sbjct: 2359 YTCDA 2363



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--H 4460
            G +    PP F  K++     E E A+F    +G P P I+WY++   +     FQ    
Sbjct: 6100 GKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              S   +L+IR    ED  ++     NR G+A+ SA L ++    Q +
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQ 6207



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 763 EEQTSQRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           + Q S  P+F+ RP   +  +  G++A    Q+  V +PT +V W KD +P+ A +R   
Sbjct: 3   QPQFSGAPRFLTRPKAFV--VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRL 58

Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
             +     L I+ L   D+G Y  RA N +GEA +   ++V A +
Sbjct: 59  AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEA 103



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 5/98 (5%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FG 3338
            PP+F+ +++  +  VEG+ A F   +     P ++  W+ +G  L  G++++T  +   G
Sbjct: 6107 PPRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 6163

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
            +++L I    +E+ G YEC   N+LG     A L+  S
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND--FG 3751
            PPRF  +++ +  V EG    F C +E  G P  +I W+ +G    TG++  TL++   G
Sbjct: 6107 PPRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 6163

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + L I      D G Y C   N+ GSA  +A++
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAEL 6197



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 88/408 (21%), Positives = 146/408 (35%), Gaps = 57/408 (13%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++P  F + ++   V E   A           P +KW   N  ++    + +        
Sbjct: 3182 ARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLE 3240

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L++R +  +DS  ++       G    SA L V           +P  F    +N   T 
Sbjct: 3241 LVVRNLRPQDSGRYSCSF----GDQTTSATLTVTA---------LPAQFIGKLRNKEATE 3287

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ-DSGKYEC 4586
            G    L  +++   P++  W K G +   D     L +DG    L +      D+ +Y C
Sbjct: 3288 GATATLRCELSKAAPVE--WRK-GSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC 3344

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            V     GE R  A   +         +P       P   I  L+ +   EG      C++
Sbjct: 3345 VC----GEERTSASLTI---------RPM------PAHFIGRLRHQESIEGATATLRCEL 3385

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
              K  P V+W KG + ++      + +      L+I      D G+Y CV        T+
Sbjct: 3386 -SKAAP-VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATL 3443

Query: 4707 AAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
              K           LPA     LR+    EG  A    ++ SK+ P ++W +    + + 
Sbjct: 3444 TVKA----------LPAKFTEGLRNEEAVEGATAMLWCEL-SKVAP-VEWRKGPENLRDG 3491

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  EG    L I      D G + C      GQ  TSA L +++
Sbjct: 3492 DRYILRQEGTRCELQICGLAMADAGEYLC----VCGQERTSATLTIRA 3535



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 2/104 (1%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F+   K+     G       +I  VG+PT ++ W K+ Q + A +RF          L
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRL 67

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQH 740
            +L L + DSG+Y CRA +A G A     L V   A     + H
Sbjct: 68  TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 2/81 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            VS GK+  L C++  +G+PT +V W  + + V  G+RF+   D     L I+     D+G
Sbjct: 21   VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSG 78

Query: 1249 EYTVRAVNHLGSAHTSAIVRV 1269
            +Y  RA N +G A  +  ++V
Sbjct: 79   QYVCRARNAIGEAFAAVGLQV 99



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 57/230 (24%), Positives = 91/230 (39%), Gaps = 19/230 (8%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL--PSGTRYKSTHDFSYVSL 2833
            F+    +I  +EG    F C V  S  P   + W  + + L  P G R +        +L
Sbjct: 112  FLLRPTSIRVREGSEATFRCRVGGSPRPA--VSWSKDGRRLGEPDGPRVRVEELGEASAL 169

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             I      D G Y  +A N  G+A+ + +L    D             A L  +++  EA
Sbjct: 170  RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
              A+G   S P T                + EG+   L   V    +P  +  W  +G++
Sbjct: 230  MRAEGAPASPPSTG----------TRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQL 277

Query: 2954 LEQGSRFKLTSDF--GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + +G R  +  D    FV L ++   + D G+YTC A N  G+ ++S  V
Sbjct: 278  VTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 58/224 (25%), Positives = 95/224 (42%), Gaps = 20/224 (8%)

Query: 2242 PRFVTELRGTT-HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL--QSAARFHITFDFG 2298
            P F+  LR T+  V EG  A F C+V     P   + +  +G+ L      R  +  + G
Sbjct: 110  PHFL--LRPTSIRVREGSEATFRCRVGG--SPRPAVSWSKDGRRLGEPDGPRVRVE-ELG 164

Query: 2299 YVS-LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELE 2357
              S L I+   P D G Y V+A N LG  ++A ++ V +  +  +          +  L+
Sbjct: 165  EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ 224

Query: 2358 SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK 2417
                  R E   P +   P  T        + EG+ A   C +   G+P  +  W ++ +
Sbjct: 225  RRREAMRAE-GAPAS---PPSTG--TRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQ 276

Query: 2418 LIEDSSRITKTHDF--GYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            L+ +  R     D    +V + I   +  D G+Y C ASNL+G+
Sbjct: 277  LVTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQ 319



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 93/458 (20%), Positives = 173/458 (37%), Gaps = 54/458 (11%)

Query: 4362 VAKQKQTQKEVVG--DKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK--KM 4417
            ++   + + E VG   + + ++    E  E   +A  Q+      V   +P I  +  + 
Sbjct: 1666 LSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAELEPQISERPCRR 1725

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477
            +P  V EHE               + W ++   I+ S   +  +      L +    V D
Sbjct: 1726 EPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLD 1785

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            SA+++     R G       + VEE         V   F    + V    G  V L  ++
Sbjct: 1786 SAIYSC----RVGAEGQDFPVQVEE---------VAAKFCRLLEPVCGELGGTVTLACEL 1832

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
            +     +V W     +++   R +++ E    +L +L    +D+G+Y C     + +   
Sbjct: 1833 SPACA-EVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVC----ESRDDHT 1887

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             A+  VS+P                 + +  L   +  EG    F C +V      V W+
Sbjct: 1888 SAQLTVSVPRVV--------------KFMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWF 1932

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            +   L++PS+ F +S++   ++L IS+   ED G     A  ++     +A L+V +   
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASS----SAALRVRE--- 1985

Query: 4718 ADNLPAL--TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                P L    L    V E      + ++T +  P ++W R    +    + ++  EG  
Sbjct: 1986 ---APVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGAR 2041

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              L++ N    D G F C         +T AKL V+ +
Sbjct: 2042 HRLVLHNVGFADRGFFGCETP----DDKTQAKLTVEMR 2075



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 13/212 (6%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P  F  PL+ V   E  K+  E  +     P + + WLK+G  + A        +    S
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACRS 2221

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L +      D G Y C A  A   A  K V   T      R     E    IQ + + ++
Sbjct: 2222 LTIYRCEFADQGVYVCDAHDAQSSASVK-VQGRTYTLIYRRVL--AEDAGEIQFVAENAE 2278

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
             + Q  ++E        +RPL+D   +++ R    E Q   VS  + +V W+K  + +  
Sbjct: 2279 SRAQLRVKELP---VTLVRPLRDKIAMEKHRGV-LECQ---VSRASAQVRWFKGSQELQP 2331

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
              +   + +  Y  L I  + AED  +YT  A
Sbjct: 2332 GPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 10/161 (6%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +P  EVTW+ + +++    + K+ +   G    L++  V  +D+G  +
Sbjct: 1181 GTTAMLSCEVA-QPQTEVTWYKDGKKLSS--SSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A  +    +FQ  L++ E + V A + +   + +    G    L+       T  +TW
Sbjct: 1238 CEAGGQ--RVSFQ--LHITEPKAVFAKEQLVH-NEVRTEAGASATLSCEVAQAQT-EVTW 1291

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             KDG  +  + ++RI   G    L + +A  +DA  Y C A
Sbjct: 1292 YKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 8/137 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FG 2298
            PPRFV ++R +  V EG+ A F C +E    P +R  +Y +G  L +  +F    +   G
Sbjct: 6107 PPRFVNKVRASPFV-EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 6163

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL---EKIRE 2355
             + L I+    ED G Y  + +N LG   ++  + + +      E    E L    ++ E
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 6223

Query: 2356 LESAEPFKRPEIPEPVT 2372
             E+  P K   I E +T
Sbjct: 6224 QETKVPKKTVIIEETIT 6240



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 51/200 (25%), Positives = 75/200 (37%), Gaps = 14/200 (7%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR-FTPIYDF 4028
            +Q P F+ +  S       E T F C++   G P   V W  +G+ L   +     + + 
Sbjct: 107  EQAPHFLLRPTSIRVREGSEAT-FRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 4029 GYV-AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKI 4087
            G   A+      P D G Y  RA N  G     A +       +V         +     
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAAL-------VVDSDAADTASRPGTST 216

Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
              + A  Q   E +  E     PP   +     TV EG+ AR  C VTG PKP  +W  +
Sbjct: 217  AALLAHLQRRREAMRAEGAPASPPSTGTR--TCTVTEGKHARLSCYVTGEPKPETVWKKD 274

Query: 4148 GNTIVNGSRYKLTYDGMYHF 4167
            G  +  G R+ +  D   +F
Sbjct: 275  GQLVTEGRRHVVYEDAQENF 294



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 76/280 (27%), Positives = 111/280 (39%), Gaps = 31/280 (11%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKA--GSRFRTFCDF 3475
            +AP F +  ++I  +REG  A F  R+  +  P   V W  +G+ L    G R R     
Sbjct: 108  QAPHFLLRPTSIR-VREGSEATFRCRVGGSPRP--AVSWSKDGRRLGEPDGPRVRVEELG 164

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKI 3535
                L I    P D G Y  RA N  G A   A++ V        ++       GT    
Sbjct: 165  EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS------DAADTASRPGT-STA 217

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A L       + +  E    +PP  +T      ++E   A   C +    +      W  
Sbjct: 218  ALLAHLQRRREAMRAEGAPASPP--STGTRTCTVTEGKHARLSCYV--TGEPKPETVWKK 273

Query: 3596 NGKPLLTGSRVKTINDFGF-VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQG 3654
            +G+ +  G R     D     +L+I    Q D GLYTC A+N  G+ T S  L V     
Sbjct: 274  DGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-TYSSVLVV----- 327

Query: 3655 IILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNP 3694
             + EP +P  FK   + +Q LE  + ++E  T   E P P
Sbjct: 328  -VREPAVP--FK---KRLQDLE--VREKESATFLCEVPQP 359



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 67/288 (23%), Positives = 114/288 (39%), Gaps = 24/288 (8%)

Query: 2941 PDLKIEWYFNGKVLEQ--GSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P   + W  +G+ L +  G R ++        L +     RD G Y  +A N  G A  +
Sbjct: 137  PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
            + +   S  +  +    P GT     + +L+   R+    + +     PP   T      
Sbjct: 197  AALVVDS--DAADTASRP-GTSTAALLAHLQ---RRREAMRAEGAPASPPSTGT---RTC 247

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTT 3116
             ++EG+  H   S   TG+      W  +G+ +    R   VY  A    VL+IL  K +
Sbjct: 248  TVTEGK--HARLSCYVTGEPKPETVWKKDGQLVTEGRR-HVVYEDAQENFVLKILFCKQS 304

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G Y+C A+N  GQ   SV +   + +   K R    +Q++E +++ +SA F C    V
Sbjct: 305  DRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKR----LQDLE-VREKESATFLC---EV 356

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              P  +  W+     +  S +     +     L +      D   Y+C
Sbjct: 357  PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC 404



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 5/137 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--R 690
            V  PP+F+  +++   +EG    F   IE  G P  +I W K+G  +   ++F ++   R
Sbjct: 6104 VQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPR 6161

Query: 691  FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQHPETLQYIQQ 749
             G + L + + + +D G Y C  V+  G A   A L + +P    +      + +  ++ 
Sbjct: 6162 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEV 6221

Query: 750  LEDYSKYQHQESIEEQT 766
             E  +K   +  I E+T
Sbjct: 6222 TEQETKVPKKTVIIEET 6238



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 3/95 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F T  K++   V G+   L  Q+     P  ++ W K+   +  GAR +   D  L 
Sbjct: 9    APRFLTRPKAFVVSV-GKDATLSCQIVGNPTP--QVSWEKDQQPVAAGARFRLAQDGDLY 65

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             L+I  L   DSG Y C+A N +GEA +   ++++
Sbjct: 66   RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 73/320 (22%), Positives = 126/320 (39%), Gaps = 35/320 (10%)

Query: 2993 GEAFTSSTVY---CTSKDNLIERTQHPKGTEG--LEKIQN-LEDSLRKEPGQQPDDDTGR 3046
            G+A  +S+VY   C    + +   + P    G  L+ + N +E S+R E    P     +
Sbjct: 648  GQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANK 707

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPT-GDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP      ++++        H EA L+    DQ+  + W  +G+T+    +     + G 
Sbjct: 708  PP--AAAAREVL-----ARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGR 760

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
             VL +      D+G Y C   ++ G+    + ++ + +    K    + +  +     G 
Sbjct: 761  RVLLVRDVARDDAGLYEC--VSRGGRIAYQLSVQGLARFL-HKDMAGSCVDAVA----GG 813

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYT-QNHDSGEYVC 3224
             A FEC      +  + + WY +G  + HS       D G     +A T    D G Y C
Sbjct: 814  PAQFEC---ETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            R     GED     +       V+ +    + LA+ R+L++  GA   T S   A+    
Sbjct: 871  RV----GEDSVDFRLRVSEPKVVFAK----EQLAR-RKLQAEAGA-SATLSCEVAQAQTE 920

Query: 3285 ITQIQDVTKLVEGQSAHFEA 3304
            +T  +D  KL        EA
Sbjct: 921  VTWYKDGKKLSSSSKVCMEA 940



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 12/163 (7%)

Query: 1701 SAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            S   +++ Q P  F   ++     E + A F   +   G P  ++ W ++G  +   N+ 
Sbjct: 6097 STLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKF 6154

Query: 1760 TTMHD--FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH-ES 1816
             T+ +   G + L ++  + ED G Y C  +N LG A  S+ L +QS      E  H E 
Sbjct: 6155 QTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQ 6214

Query: 1817 ALQKIQQLEDSSRYQRR----EDVEVAVNQAPRFITQLNGPTK 1855
             +  ++  E  ++  ++    E+    V ++PR   Q   P+K
Sbjct: 6215 LVAAVEVTEQETKVPKKTVIIEETITTVVKSPR--GQRRSPSK 6255



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 50/198 (25%), Positives = 77/198 (38%), Gaps = 9/198 (4%)

Query: 2007 PTMRVEWYCNGRPVQQ--GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            P   V W  +GR + +  G R +        AL I  A   D GTY  +A N +G A   
Sbjct: 137  PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196

Query: 2065 SSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEG 2124
            +++ VD+ +              +  L++  R     E  P   P   +  T    + EG
Sbjct: 197  AALVVDSDAADTASRPGTSTAALLAHLQR-RREAMRAEGAPASPP---STGTRTCTVTEG 252

Query: 2125 DRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY-VALDILYTYAEDSGTYM 2183
              A   C V    +P     W  +GQ +  G R+    D      L IL+    D G Y 
Sbjct: 253  KHARLSCYVT--GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYT 310

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C A+N +G+  ++  + V
Sbjct: 311  CTASNLVGQTYSSVLVVV 328



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 4/147 (2%)

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
            D+ T    + ++++  +   AA +  +VR+++   + P FS    + E   G  + LEC 
Sbjct: 4861 DLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECV 4920

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTG-HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            +    D  +R  W  +G  +  G H           +L +  +   D+G YTCQ +N+ G
Sbjct: 4921 VASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFG 4978

Query: 1393 EAVTSCALRVIAKKDLILESQHPSGLE 1419
            + VT  A  V++  +   ES     L+
Sbjct: 4979 Q-VTHSACVVVSGSESEAESSSGGELD 5004



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            +++ Q    P FLT   +   +  G  A   C++  + +P   + W  + Q + AG R+R
Sbjct: 1    MDQPQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFR 57

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               D     L IL     DSG Y+C+A N +GEA     L+V
Sbjct: 58   LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 58/269 (21%), Positives = 102/269 (37%), Gaps = 33/269 (12%)

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  V W K+   + P  + K+  E     L IL   P D+G Y C     AG A    E 
Sbjct: 2496 PKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC----QAGSAHSSTEV 2551

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V                     +  PL+D    E     FSC++  +    V+W     
Sbjct: 2552 TVEAREV---------------TVTGPLQDAEATEEGWASFSCELSHED-EEVEWSLNGM 2595

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +    + ++S     +TL +      D G    +   S+ +V+ +A+L+V    +   +
Sbjct: 2596 PLYNDSFHEISHKGRRHTLVLKSIQRADAG----IVRASSLKVSTSARLEV----RVKPV 2647

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L  L D+   E      + ++ S  +  + W ++G  +  +  +  +H      L++ 
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVH 2706

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED G +TC      G  ET A++ V
Sbjct: 2707 DVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 15/187 (8%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F++  Q ++V EG      C ++ R    V W     Q+     ++ +V +     L++
Sbjct: 3980 RFLRELQHQEVDEGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQ-MVQDGAAAELLV 4037

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
              V   D+G  TC     +G T     L+V    +V  PKF  R  +L    G+   L  
Sbjct: 4038 RGVEQEDAGDYTC----DTGHTQSMASLSV----RVPRPKFKTRLQSLEQETGDIARLCC 4089

Query: 513  RAVGTPTPRIT-WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +     +  +  W K+GV +   P+  + + G    L I + +A D   Y C    V G 
Sbjct: 4090 QLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC----VTGG 4145

Query: 572  TATRARL 578
              T A L
Sbjct: 4146 QKTAASL 4152



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 8/101 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL------VECNKYSMRYNE 124
            PP   + F   +  +G +  F  K+ G P P V W R++A         +   Y++  + 
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
            Q    SL++  +G   +G YTC A N  G+A+CS  +   G
Sbjct: 5430 QQH--SLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSG 5468



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 64/239 (26%), Positives = 88/239 (36%), Gaps = 22/239 (9%)

Query: 768  QRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI-TASSRITSIFNF 825
            Q P F+ RP      ++EG  A F  ++     P   V W KDGR +         +   
Sbjct: 108  QAPHFLLRPTSI--RVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 826  GYVS-LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKT 884
            G  S L I   R  D G+Y VRA N LG A + A++ V + +  TA       R      
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTAS------RPGTSTA 217

Query: 885  XXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVE 944
                              P S      +T      ++ EG  A     +   G+      
Sbjct: 218  ALLAHLQRRREAMRAEGAPASPPSTGTRT-----CTVTEGKHARLSCYVT--GEPKPETV 270

Query: 945  WLKDGRPVEASSRITTFFNFGY-VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG+ V    R   + +      L I      D G YTC A N +GQ T S+ L +V
Sbjct: 271  WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-TYSSVLVVV 328



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 3/90 (3%)

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            SA+ EV  +  VF   + D+   E      +     V DP+  V W ++GV +  S++  
Sbjct: 2637 SARLEVRVKPVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYD 2693

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
             +H  G   L +  V+PED+G YTC   +E
Sbjct: 2694 FLHTAGTRGLVVHDVSPEDAGLYTCHVGSE 2723



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSG 3491
            EGE+A F   +     P ++  WY +G  L  G++F+T  +   G ++L I     ED G
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 3492 EYLCRAYNNYGEAVTTASMKVQ 3513
             Y C   N  G A  +A +++Q
Sbjct: 6179 LYECELVNRLGSARASAELRIQ 6200



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 54/215 (25%), Positives = 87/215 (40%), Gaps = 12/215 (5%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            VT  P   +RP       E + V  EC+L   +  N+ V W K+G  +  G         
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQG 2217

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559
               +L I      D G+Y C A +       S ++  R+ T I R    E   E IQ + 
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHD--AQSSASVKVQGRTYTLIYRRVLAEDAGE-IQFVA 2274

Query: 1560 DRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKP 1619
            + ++      V E+    P+  T ++ +  K     H       VS A+ +V W+  ++ 
Sbjct: 2275 ENAESRAQLRVKEL----PV--TLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQE 2328

Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
            L+ G ++   ++  +  L I     ED  TYTC A
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 56/237 (23%), Positives = 95/237 (40%), Gaps = 21/237 (8%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++V  E + +  EC  E SR P + + W  +   L +G         +  SL I
Sbjct: 2168 FSRPLQDVVTTEKEKVTLEC--ELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                  D G+Y C A +++ SA+     R      + +     +    ++ V +  E+R 
Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQGRTY---TLIYRRVLAEDAGEIQFVAENAESR- 2280

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLE 2955
            A+ R   +P T        I +     ++E QV     QV           W+   + L+
Sbjct: 2281 AQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVR----------WFKGSQELQ 2330

Query: 2956 QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
             G +++L SD  +  L + DV+  D   YTC A    G+  TS+  +   +   I R
Sbjct: 2331 PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEEQSITIVR 2383



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ +   PRF+  ++ +   VEG+ A F   +E        + WY +G  +T+ N+ QT 
Sbjct: 6101 KILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAP--YPQIRWYKDGALLTTGNKFQTL 6157

Query: 1096 HD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             +   G + L I +   ED G+Y     N  G A+ SA + +++         HR
Sbjct: 6158 SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 6212



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/112 (26%), Positives = 57/112 (50%), Gaps = 4/112 (3%)

Query: 2234 VEEPKIS-PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292
            +++P+ S  PRF+T  +    V  GK A   CQ+  V +P  ++ +  + + + + ARF 
Sbjct: 1    MDQPQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFR 57

Query: 2293 ITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344
            +  D     L I      D+G+Y  +A NA+G   +A+ + V A+ +   ++
Sbjct: 58   LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA 109



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            PRF    K  + V  G      C++  VG+PT ++ W  + +P A G+R     D     
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            L I  +   D+G+Y CRA N  G A     +   A+
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 18/195 (9%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            ++ +AL  +F++  ++++  EG      C ++ +  P V W      +R    + +   +
Sbjct: 3795 LTVRALPARFIEDVKNQEAREGATAVLQCELS-KAAP-VEWRKGSETLRGGDRYSL--RQ 3850

Query: 445  SGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
             G    L I  ++++D+G  +CV     G+      L V    +   P F E   +L   
Sbjct: 3851 DGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTV----RAPQPVFREPLQSLQAE 3902

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            EG    L    +  PT  + W K G+ +  N        G  + L +   +  D   Y C
Sbjct: 3903 EGSTATLQCE-LSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC 3961

Query: 564  TAQNVAGSTATRARL 578
            T     GS AT A L
Sbjct: 3962 T----CGSQATSATL 3972



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/92 (28%), Positives = 43/92 (46%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F    + + F +G +A+F   + G P P + W +  A L   NK+      ++G + 
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 6166

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            L+I+     D G Y C   N+ G A  S  ++
Sbjct: 6167 LVIRAASKEDLGLYECELVNRLGSARASAELR 6198



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSG 2180
            EG+ A F C +E    P+  I W+ +G  +  G++++T  +   G + L I     ED G
Sbjct: 6121 EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
             Y C+  N+LG A  +  L++
Sbjct: 6179 LYECELVNRLGSARASAELRI 6199



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F    K   V+  + A    ++  VG+P  +V W ++  P+ A  R     D     
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814
            L +  +   DSG Y CRA N +GEA  +  L V ++A+   ++ H
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 56/218 (25%), Positives = 79/218 (36%), Gaps = 13/218 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKM--GSRFRTTHDFGFVTLDINSVVANDAG 2579
            EG  A +  RV   G P     W  +G  L    G R R         L I +    D G
Sbjct: 123  EGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG 180

Query: 2580 LYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQ 2639
             Y  +A N  G                 D A RP +     L  A + +  E     G  
Sbjct: 181  TYEVRAENPLGAASAAAALVVDSDAA--DTASRPGTSTAALL--AHLQRRREAMRAEGAP 236

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
             +P  T        + EG+H  L   V    +P  +  W K+G  +T G R     D   
Sbjct: 237  ASPPSTGTRTC--TVTEGKHARLSCYVTG--EPKPETVWKKDGQLVTEGRRHVVYEDAQE 292

Query: 2700 -VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               L I   +  D G+YTC A+NL+G+  S+  + + +
Sbjct: 293  NFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 58/217 (26%), Positives = 97/217 (44%), Gaps = 28/217 (12%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA---NL 999
            V WLKDG  + A   +         +LTI      D G Y C A++A   A+        
Sbjct: 2196 VRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTY 2255

Query: 1000 TIVTKKDIIAESQHPGGLEKIQYL-EDASRYSKRTEEEVKITQKPRFLGPLKGTNKI-VE 1057
            T++ ++ ++AE        +IQ++ E+A   ++   +E+ +T     + PL+  +KI +E
Sbjct: 2256 TLIYRR-VLAED-----AGEIQFVAENAESRAQLRVKELPVT----LVRPLR--DKIAME 2303

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
                  E +V   S  +  V W+   +++    + +   D  Y  L I+ V AED   YT
Sbjct: 2304 KHRGVLECQV---SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYT 2360

Query: 1118 VVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKT 1154
                  AG+ + SA   VE +S     +I RGL + T
Sbjct: 2361 C----DAGDVKTSAQFFVEEQS----ITIVRGLQDVT 2389



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP   T  K   +  G+ A    ++  V + T +V W  + +P+ +G+RF    +     
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEA 1661
            L I+     DSG Y CRA NA+GEA
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEA 91



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 43/198 (21%), Positives = 81/198 (40%), Gaps = 11/198 (5%)

Query: 370  YITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            Y  + + +    R+ I+E K +  +   V  +     G      C V  +   EVTW+ +
Sbjct: 1052 YSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVA-QAQTEVTWYKD 1110

Query: 429  DRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
             +++    + K+ +   G    L++     +D+G  +C A    G       L++ E + 
Sbjct: 1111 GKKLSS--SSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA----GGQRVSFHLHITEPKG 1164

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
            V A K     + +    G   +L+   V  P   +TW KDG  +  + ++R+   G    
Sbjct: 1165 VFA-KEQSVHNEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRR 1222

Query: 548  LDIPRAKASDAAWYQCTA 565
            L + +   +DA  Y C A
Sbjct: 1223 LVVQQVGKADAGEYSCEA 1240



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 41/199 (20%), Positives = 81/199 (40%), Gaps = 11/199 (5%)

Query: 369  QYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
            +Y  +   +     + ++E KA+  +     ++     G      C V  +   EVTW+ 
Sbjct: 1511 EYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTEVTWYK 1569

Query: 428  NDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
            + +++    + K+ +   G    L++     +D+G  +C    K+G+      L+V E +
Sbjct: 1570 DGKKLSS--SSKVRMEAVGCTRRLVVQEAGQADAGEYSC----KAGDQRLSFHLHVAEPK 1623

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
             V A K       +    G    L+       T  +TW KDG  +  + ++R+   G   
Sbjct: 1624 VVFA-KEQPAHREVQAEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRVEAVGCTR 1681

Query: 547  TLDIPRAKASDAAWYQCTA 565
             L + +A  ++A  Y C A
Sbjct: 1682 RLVVQQAGQAEAGEYSCEA 1700



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 55/235 (23%), Positives = 98/235 (41%), Gaps = 15/235 (6%)

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            L   P   +V+ G       ++ + +D+ + Y  D    +T  +  + E+++    V+  
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDT-YTCDAGDVKTSAQFFVEEQSIT--IVRGL 2385

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            QD  V E     F+C  +        W +    ++   N   L  E   H LM+     +
Sbjct: 2386 QDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVG-LEQEGTVHRLMLRRTCST 2444

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
             +G V        G++    RL V+    VV  + +E  +    RE + VVL+      P
Sbjct: 2445 MTGPVHFTV----GKSRSSARL-VVSDIPVVLTRPLEPKTG---RELQSVVLSCDF--RP 2494

Query: 519  TPR-ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P+ + W KD  P+ P+ + ++  +G  + L I R   +DA  Y+C A +   ST
Sbjct: 2495 APKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSST 2549



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-F 691
            V+ PP F   L   TA  G  +    R+   G P   I W K+G++++       I    
Sbjct: 6010 VWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPD 6067

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
            G  +L + SL   DSG+Y C A SA G   T  K ++ V PR
Sbjct: 6068 GSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPR 6109



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P F++ P A  V  G+ A   C++ G+P P+V W  +   +  G+R++L  DG +Y   I
Sbjct: 10   PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 4170 PKTRQYDTGK 4179
                  D+G+
Sbjct: 70   LDLALGDSGQ 79



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 54/238 (22%), Positives = 94/238 (39%), Gaps = 23/238 (9%)

Query: 1573 VTTQAPIC-TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631
            V T+ P+  +  L++V   E ++   E  L   S   + V W  +   L++G        
Sbjct: 2160 VVTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQ 2216

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691
                +L I  C   D G Y C A +A             S  S+ ++ +    + R    
Sbjct: 2217 GACRSLTIYRCEFADQGVYVCDAHDA------------QSSASVKVQGRTYTLIYRRVLA 2264

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLI---PVGDPKLRVEWLR 1748
            ED  + Q  +   E   Q  V  +P+  +R   ++ A  + R +    V     +V W +
Sbjct: 2265 EDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFK 2324

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
                ++   +   + D  Y  L +  V+ ED  TYTC A    G+  TS+  FV+ ++
Sbjct: 2325 GSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEEQS 2378



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/350 (21%), Positives = 129/350 (36%), Gaps = 24/350 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P  +TRP   +   E Q V   C   P   +   V+W+K+  P++   +F+   +     
Sbjct: 2468 PVVLTRPLEPKTGRELQSVVLSCDFRPAPKA---VQWYKDDTPLSPSEKFKMSLEGQMAE 2524

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L I+ L+  D+G+Y C+A +   + EV+  +  R  T +    Q+    E+         
Sbjct: 2525 LRILRLMPADAGVYRCQAGSAHSSTEVT--VEAREVT-VTGPLQDAEATEEGWASFSCEL 2581

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
             H  + V+      P+   S   +  K G+R     + I  +DA   +    + K   S 
Sbjct: 2582 SHEDEEVEWSLNGMPLYNDSFHEISHK-GRRHTLVLKSIQRADA--GIVRASSLKVSTSA 2638

Query: 1624 SRFTETNNFGFV-ALDIMSCLPEDSGTYTCRAINALGEAV--TSGIAIVHSKKSIYLESQ 1680
                      F+ ALD +S     +    C   +     V    G+ +  S K  +L + 
Sbjct: 2639 RLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTA 2698

Query: 1681 -HEGALPRLNQLEDTSKYQRHSAQDEVITQAPV------FTMPMKDIRVAENQAAHFEAR 1733
               G +      ED   Y  H   +E   +  V       T  +K + V E ++  FE  
Sbjct: 2699 GTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECV 2758

Query: 1734 LI--PVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSG 1781
            L      DP +   W   G  + +S+R           L ++   P D+G
Sbjct: 2759 LSHESASDPAM---WTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG 2805



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F    +N     G    F+  + G P P V W  K   L+E + + M   +Q G   L
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWF-KDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 132  LIKQIGPGDEGEYTCTARNQYG 153
            +I  + P D G Y C A N  G
Sbjct: 5185 IITAVVPADMGVYRCLAENSMG 5206



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 98/470 (20%), Positives = 184/470 (39%), Gaps = 65/470 (13%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            V+W +    L   +K  M     T    L++ Q G  D GEY+C A  Q       +  +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTR--RLVLPQAGKADAGEYSCEAGGQRVSFHLHI-TE 1161

Query: 163  PEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR-QTQKVAYTNGTDHSSTDDF 221
            P+G              + V   V+ +A  T   + E ++ QT+   Y +G   SS+   
Sbjct: 1162 PKGVFAKE---------QSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKV 1212

Query: 222  KVDTFEYRLLREVSFRESITKRYVGESDVQISTE-IDRSLGPVSPPKIAQKPR----NSK 276
            +++       R +  ++ + K   GE   +   + +   L    P  +  K +      +
Sbjct: 1213 RMEV--KGCTRRLVVQQ-VGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVR 1269

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             + GA A    +++   +  VTW+K+G++L +S+K  I        L V+   ++D+G Y
Sbjct: 1270 TEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T  A    G    S +L V  P   + ++Q +             +++    A+A    +
Sbjct: 1329 TCEA----GGQRLSFHLDVSEPKAVFAKEQLA-----------HRKVQAEAGAIATLSCE 1373

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNV 455
            V Q +  TE                 VTW+ + +++    + K+ +   G    L++   
Sbjct: 1374 VAQAQ--TE-----------------VTWYKDGKKLSS--SSKVRMEAVGCTRRLVVQQA 1412

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
              +D+G  +C    ++G       L+V E  +VV  K       +  + G    L+    
Sbjct: 1413 CQADTGEYSC----EAGGQRLSFSLDVAE-PKVVFAKEQPVHREVQAQAGASTTLSCEVA 1467

Query: 516  GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
               T  + W KDG  +  + ++R+   G    L + +A  + A  Y C A
Sbjct: 1468 QAQT-EVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA 1516



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 113/481 (23%), Positives = 190/481 (39%), Gaps = 51/481 (10%)

Query: 1998 EATLTPVNDPT-MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
            EAT   V  P+ + V W+ +G  +Q   +F  +      +L I     ED G    +A  
Sbjct: 1915 EATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG 1974

Query: 2057 AVGEA-VTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKP-------IEEEQPGQR 2108
            A   A +      V  K  L   T++E R     E+E   RP P            PG+ 
Sbjct: 1975 ASSSAALRVREAPVLFKKKLEPQTVEE-RSSVTLEVE-LTRPWPELRWTRNATALAPGKN 2032

Query: 2109 PVFLTALTS-----LENLKEGDRAHFECRV-EPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
             V + A  +     L N+   DR  F C   +      LT++      ++  G +     
Sbjct: 2033 -VEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM--RQVRLVRGLQAVEAR 2089

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII-LDTQHP--NGLEK 2219
            + G   +++  ++A+  G++         +   TC L V G  + + L    P  +GL  
Sbjct: 2090 EQGTATMEVQLSHADVDGSWTRDGLRF--QQGPTCHLAVRGPMHTLTLSGLRPEDSGL-M 2146

Query: 2220 IRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
            + + E    S R+ V E  +S  R + ++  T    E +    EC++     PN+ + + 
Sbjct: 2147 VFKAEGVHTSARLVVTELPVSFSRPLQDVVTT----EKEKVTLECELSR---PNVDVRWL 2199

Query: 2280 HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKG- 2338
             +G  L++     I       SL I  C   D G Y   A +A     S+ S+ V  +  
Sbjct: 2200 KDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTY 2255

Query: 2339 SIISESQRPEGLEKIREL-ESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNI-QEGQTAH 2395
            ++I      E   +I+ + E+AE   +  + E PVT  RP+        D I  E     
Sbjct: 2256 TLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLR-------DKIAMEKHRGV 2308

Query: 2396 FDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
             +C+   V   + +V WF+  + ++   +     D  Y  + IS V  EDE  Y C A +
Sbjct: 2309 LECQ---VSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD 2365

Query: 2456 L 2456
            +
Sbjct: 2366 V 2366



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 8/109 (7%)

Query: 635  PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            P P F  PL+S+ A EG     +  +    +PT  + W K G  ++A+ R     +    
Sbjct: 3888 PQPVFREPLQSLQAEEGSTATLQCELS---EPTATVVWSKGGLQLQANGRREPRLQGCTA 3944

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR-ATIERTSQHPE 742
             L +  L  +D+GEYTC      G   T A L VT       R  QH E
Sbjct: 3945 ELVLQDLQREDTGEYTC----TCGSQATSATLTVTAAPVRFLRELQHQE 3989



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN--FGY 827
            P+F+  ++      EG +A F   +     P +R  WYKDG  +T  ++  ++     G 
Sbjct: 6108 PRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            + L I     ED G Y    VN+LG A ++A +R+
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 10/120 (8%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            AA +GY      +  E +    P F+ T  D       +   EC  +  + + +R  W  
Sbjct: 4881 AAFKGYK-----VRKEMKQQEGPMFSHTFGDTEAQVGDALRLEC--VVASKADVRARWLK 4933

Query: 3596 NGKPLLTGSR--VKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G  L  G    +  + D G   L I G+ + DAG YTC+ +N+ G+ T S  + V G +
Sbjct: 4934 DGVELTDGRHHHIDQLGD-GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSE 4992



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 2/72 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +  G+ A   C++  VG+PT +V W ++++ +   +R     D     +TI  +   D G
Sbjct: 21   VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSG 78

Query: 2448 VYMCRASNLLGE 2459
             Y+CRA N +GE
Sbjct: 79   QYVCRARNAIGE 90



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/76 (28%), Positives = 39/76 (51%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            +P  ++ W  + + +  G+RF+L  D     L ++D+   DSG Y C+A N  GEAF + 
Sbjct: 36   NPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95

Query: 3000 TVYCTSKDNLIERTQH 3015
             +   ++    E+  H
Sbjct: 96   GLQVDAEAACAEQAPH 111



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN------FPIKNSPDFQIHTFS 4463
            PP   ++  P +V +     F V+ +G P+P + W RE       +   ++P + + + +
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +  L++  V  +    +  +A N  G A CSA+L V
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 4/124 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYV 2035
            P+F   ++ +   EG       T+     P +R  WY +G  +  G++F+T  +   G +
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLL 6165

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L I  A  ED G Y C+  N +G A  ++ +++ +      +    ++L    E+ + E
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQE 6225

Query: 2096 RPKP 2099
               P
Sbjct: 6226 TKVP 6229



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R         L +      D+G YSC A    G   +S +L   
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSFQLHIT 1252

Query: 3142 D-KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            + K+   K +    + N    + G SA   C V        ++ WY +G+ +  S++++ 
Sbjct: 1253 EPKAVFAKEQL---VHNEVRTEAGASATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRI 1306

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             +      L +      D+GEY C A
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 9/156 (5%)

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            EV W   + Q+R     + +V E    +L +  +   D+G   C +R+    T+ Q  ++
Sbjct: 1838 EVVWRCGNTQLRVGKRFQ-MVAEGPVRSLTVLGLRAEDAGEYVCESRDD--HTSAQLTVS 1894

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V    +VV  KF+   ST+   EG         V      + W +DG  + P+ +  I  
Sbjct: 1895 V---PRVV--KFMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQ 1948

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
             G + +L I      DA      A+  + S A R R
Sbjct: 1949 SGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDF 2697
            Q+ P+F+ H     +   G  + LE  V  + D  ++  W K+GV LT G          
Sbjct: 4895 QEGPMFS-HTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD 4951

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  +L I  L   D+G YTC+ +N  G+   +A + +
Sbjct: 4952 GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 66/294 (22%), Positives = 104/294 (35%), Gaps = 34/294 (11%)

Query: 82  RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGD 140
           R  +G  A F  ++ G+P P VSW++    L E +   +R  E+ G+ S L I+   P D
Sbjct: 120 RVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRV-EELGEASALRIRAARPRD 178

Query: 141 EGEYTCTARNQYGEAICSVYIQPEGXXXXXXX---XXXXXXYRHVSETVE---------- 187
            G Y   A N  G A  +  +  +                   H+    E          
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPAS 238

Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSST---DDFKV-----------DTFEYRLLRE 233
             + GT+  T  + +  +   Y  G     T    D ++           D  E  +L+ 
Sbjct: 239 PPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKI 298

Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSG 291
           +  ++S    Y   +   +       L  V  P +  K R  + +++E   A F  ++  
Sbjct: 299 LFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVP- 357

Query: 292 NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            P     WFK   RL  S K+ I        L VRN    D   Y  + E P G
Sbjct: 358 QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVY--ICETPEG 409



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 80/375 (21%), Positives = 141/375 (37%), Gaps = 44/375 (11%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S   ++        L++++    D+  ++  A    G  + S +L V 
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVA 1620

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E +      +V        + V   +G    L  +V   +  +V W K+GKK+    + +
Sbjct: 1621 EPK------VVFAKEQPAHREVQAEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVR 1673

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL-PATKDKPKPQTKAAN 4620
            +     T  L++ +A   ++G+Y C A    G+       V  L P   ++P  +     
Sbjct: 1674 VEAVGCTRRLVVQQAGQAEAGEYSCEA---GGQQLSFRLQVAELEPQISERPCRR----- 1725

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
                  EPL   +V E + I  +  +      TV W K    I+ SK  + +   D +TL
Sbjct: 1726 ------EPL---VVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTL 1776

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYE-GQPA 4738
             +  A   D   Y C       RV    +     P Q + + A    L + V  E G   
Sbjct: 1777 TVHGAQVLDSAIYSC-------RVGAEGQ---DFPVQVEEVAAKFCRLLEPVCGELGGTV 1826

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC--RAT 4796
                +++      + W      +     FQM+ EG    L +     ED G + C  R  
Sbjct: 1827 TLACELSPACAEVV-WRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDD 1885

Query: 4797 TAAGQVETSAKLVVK 4811
              + Q+  S   VVK
Sbjct: 1886 HTSAQLTVSVPRVVK 1900



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            R    + V+  P  +T+   P    E QS    C   P P     V+WY +   L    +
Sbjct: 2457 RSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKA---VQWYKDDTPLSPSEK 2513

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++ S +   A L IL +   D+G Y C+A    G A SS  + V+++E
Sbjct: 2514 FKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVEARE 2557



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFV 3887
            PP F  ++   T E  E V+  CRV     PK  I WY++GK +     +  + D  G  
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 6070

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +L +  +   DSG+Y+C A +  G   T   I  +  P  +
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFV 6111



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP FE+   +     G   K   ++ G P PV+SW  K    V+ + + +   +  G  +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISW-YKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 131  LLIKQIGPGDEGEYTCTARNQYG 153
            L++  +   D G+Y C A +  G
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAG 6094



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EG++  F C +E +  P  +I W+ +   L +G ++++  +     + L I    +ED G
Sbjct: 6121 EGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2845 IYTCKATNSKGSATTSGSLR 2864
            +Y C+  N  GSA  S  LR
Sbjct: 6179 LYECELVNRLGSARASAELR 6198



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/67 (34%), Positives = 34/67 (50%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            +P  +V W  + + + AG+RFR   D     L I      DSG+Y+CRA N  GEA    
Sbjct: 36   NPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95

Query: 3509 SMKVQGK 3515
             ++V  +
Sbjct: 96   GLQVDAE 102



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG+ A +   +     P +R  WY +G  L  G++F+T  +   G + L I +    D G
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2580 LYMCKAINRAG 2590
            LY C+ +NR G
Sbjct: 6179 LYECELVNRLG 6189



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 145/671 (21%), Positives = 247/671 (36%), Gaps = 71/671 (10%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            +S    V  +PL  P    E +++ L C   P       V+W+ +   ++   +FK   +
Sbjct: 2464 VSDIPVVLTRPLE-PKTGRELQSVVLSCDFRPA---PKAVQWYKDDTPLSPSEKFKMSLE 2519

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT-DTQNEQAIEQ--I 1288
                 L I+    AD G Y  +A    GSAH+S  V V  R   VT   Q+ +A E+   
Sbjct: 2520 GQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWA 2575

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
                + +   ++V   +  M  P ++ + H I      +  +   +Q      +R     
Sbjct: 2576 SFSCELSHEDEEVEWSLNGM--PLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLK 2633

Query: 1349 NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN------------QLGEAVT 1396
                 +   R +P       ALD LS     +    C+ ++            QLG +  
Sbjct: 2634 VSTSARLEVRVKPVVFLK--ALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDK 2691

Query: 1397 SCALRVIAKKDLILESQHP--SGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIE 1454
               L     + L++    P  +GL       + +R  +  + D  V I  R     K++E
Sbjct: 2692 YDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETR-ARVRVHDLHVGITKRL----KTME 2746

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
             V+EG+   FEC L   + S+    W   G+ V    RF+         L + +    D+
Sbjct: 2747 -VLEGESCSFECVLSHESASD-PAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDA 2804

Query: 1515 G--IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDE 1572
            G  +++ R +    T + S  L  R     +     +  +   + +E R +  R      
Sbjct: 2805 GEVVFSVRGL----TSKAS--LIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVH 2858

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
                      S K   + EG  A    R   + DA    E+    +  KS +        
Sbjct: 2859 WLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAG---EYTCEVEASKSTASLHVEEKA 2915

Query: 1633 GFVALDIMSCLPEDSGT--YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRL-- 1688
                 ++ +   E+ GT  +TC+  +     VT    ++  + S   +   EG   RL  
Sbjct: 2916 NCFTEELTNLQVEEKGTAVFTCKTEHP-AATVTWRKGLLELRASGKHQPSQEGLTLRLTI 2974

Query: 1689 NQLE--DTSKYQRHSAQDEVITQAPV------FTMPMKDIRVAENQAAHFEARLIPVG-D 1739
            + LE  D+  Y     Q +   Q  V          ++D+ V E  +A F  R+ P   +
Sbjct: 2975 SALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYE 3034

Query: 1740 PKLRVEWLRNGVPIEASNRLTTM--HDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            P   V W  +  P+ A N L  +     GY  L ++ +  +DSGT       E G+   S
Sbjct: 3035 P---VHWFLDKTPLHA-NELNEIDAQPGGYHVLTLRQLALKDSGT----IYFEAGDQRAS 3086

Query: 1798 STLFVQSKASL 1808
            + L V  K S+
Sbjct: 3087 AALRVTEKPSV 3097



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 56/243 (23%), Positives = 94/243 (38%), Gaps = 23/243 (9%)

Query: 99   PTP-VVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
            P P  V W +   PL    K+ M    Q  ++ +L  ++ P D G Y C A    G A  
Sbjct: 2494 PAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRIL--RLMPADAGVYRCQA----GSAHS 2547

Query: 158  SVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSS 217
            S  +  E                  +E  E    G   ++ E S + ++V ++       
Sbjct: 2548 STEVTVEAREVTVTGPLQD------AEATEE---GWASFSCELSHEDEEVEWSLNGMPLY 2598

Query: 218  TDDFKVDTFEYRLLREVSFRESITKRYVG---ESDVQISTEIDRSLGPVSPPKIAQKPRN 274
             D F   + + R  R     +SI +   G    S +++ST     +  V P    +   +
Sbjct: 2599 NDSFHEISHKGR--RHTLVLKSIQRADAGIVRASSLKVSTSARLEVR-VKPVVFLKALDD 2655

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
               +E      Q ++S +P   V W K+G +L  S+K++ + T     L V +    D+G
Sbjct: 2656 LSAEERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAG 2714

Query: 335  HYT 337
             YT
Sbjct: 2715 LYT 2717



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 37/162 (22%), Positives = 66/162 (40%), Gaps = 10/162 (6%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +   EVTW+ + +++    + K+ +  +G    L++     +D+G  +
Sbjct: 905  GASATLSCEVA-QAQTEVTWYKDGKKLSS--SSKVCMEATGCTRRLVVQQAGQADAGEYS 961

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A    G       L+V E + V A   V   S +    G    L+       T  + W
Sbjct: 962  CEA----GGQRLSFHLDVKEPKVVFAKDQVAH-SEVQAEAGASATLSCEVAQAQT-EVMW 1015

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
             KDG  +  + ++ +   G    L + +A  +DA  Y C A+
Sbjct: 1016 YKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEAR 1057



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 82/367 (22%), Positives = 142/367 (38%), Gaps = 35/367 (9%)

Query: 1471 VTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEV 1530
            V+D    V W K+G  +    ++  +H  G   L + D+  ED+G+YTC     VG++E 
Sbjct: 2670 VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEET 2725

Query: 1531 SCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNV--- 1587
              R+        V  T+    L+ ++VLE  S      +  E  +   + T   K V   
Sbjct: 2726 RARVRVHDLH--VGITKR---LKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSS 2780

Query: 1588 ----EIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
                  ++G++     R    SDA  +V +       K+     E        L+     
Sbjct: 2781 SRFQATRQGRKYILVVREAAPSDAG-EVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVA 2839

Query: 1644 PEDSGTYTCRAINALGEAV---TSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKY-- 1697
            P +     C    A G  V       AI  S+K  +  E      + R   L+D  +Y  
Sbjct: 2840 PGEDVELRCELSRA-GTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTC 2898

Query: 1698 ----QRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753
                 + +A   V  +A  FT  + +++V E   A F  +      P   V W +  + +
Sbjct: 2899 EVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCK---TEHPAATVTWRKGLLEL 2955

Query: 1754 EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ 1813
             AS +     +   + L +  +   DS TYTC    ++G+A + + L VQ +    +E  
Sbjct: 2956 RASGKHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLVQGRRVHIIEDL 3011

Query: 1814 HESALQK 1820
             +  +Q+
Sbjct: 3012 EDVDVQE 3018



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 45/197 (22%), Positives = 79/197 (40%), Gaps = 15/197 (7%)

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            +++ +A     ++  QD  ++EG+   F CR++     E  W +    ++ +  + I V 
Sbjct: 4242 QLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVE 4301

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            +   H L +  VTL D+G V+       G  + + +L V  K  VV  + +E    L   
Sbjct: 4302 QGTLHLLTLHKVTLEDAGTVSF----HVGTCSSEAQLKVTAKNTVV--RGLENVEAL--- 4352

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            EG   +   +         TW  D  P+    N E+    +G    L +   +  D+   
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDS--- 4409

Query: 562  QCTAQNVAGSTATRARL 578
             C    +AG   T A L
Sbjct: 4410 -CRVTFLAGDMVTSAFL 4425



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 5/114 (4%)

Query: 941  LRVEWLKDGRPV-EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            +R  WLKDG  + +           G  +L I  +   DAG YTC+  N  GQ T SA  
Sbjct: 4927 VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSA-C 4985

Query: 1000 TIVTKKDIIAESQHPGGLEKIQYLEDASRYSK--RTEEEVKITQKPRFLGPLKG 1051
             +V+  +  AES   G L+   +   A R  +  RT+   +++ +  FL   +G
Sbjct: 4986 VVVSGSESEAESSSGGELDD-AFRRAARRLHRLFRTKSPAEVSDEELFLSADEG 5038



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 9/129 (6%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAG 980
            EG  A F   +E  G    ++ W KDG  +   ++  T      G + L I++ +  D G
Sbjct: 6121 EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGL-EKIQYLEDASRYSKRT---EEE 1036
             Y C   N +G A  SA L I +      E  H   L   ++  E  ++  K+T   EE 
Sbjct: 6179 LYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEET 6238

Query: 1037 V-KITQKPR 1044
            +  + + PR
Sbjct: 6239 ITTVVKSPR 6247



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            ++ EG  AH    L   G     +EW      +    + + V       L + G +  D+
Sbjct: 3989 EVDEGGTAHLCCELSRAGAS---VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA 4045

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            G Y+C   +    A +SV++         +P+F T +Q++E  + G  A   C +   + 
Sbjct: 4046 GDYTCDTGHTQSMASLSVRV--------PRPKFKTRLQSLE-QETGDIARLCCQLSDAES 4096

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              + ++W   G  +    + +  S      L I   +  D+GEY C
Sbjct: 4097 GAV-VQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC 4141



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 22/82 (26%), Positives = 35/82 (42%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F     D +   G   R +C V  +      W  +  ++ D  +H I     G  +L+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957

Query: 452  ITNVTLSDSGVVTCVARNKSGE 473
            IT +  +D+G  TC   NK G+
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQ 4979



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-ILI 4469
            P+F  ++Q   V +     F+    G+P+P ++W+++   ++    + I+        LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I  V   D  V+  +AEN  G +   A L V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 6/132 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++     V   G +    C +  +  PT ++ W  + +P+ +G R++   D     L I
Sbjct: 12   FLTRPKAFVVSVGKDATLSCQIVGN--PTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQH----PQGKAGLEAVEQAE 2891
                  DSG Y C+A N+ G A  +  L+   +        H    P      E  E   
Sbjct: 70   LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATF 129

Query: 2892 EARLAKGRRPSV 2903
              R+    RP+V
Sbjct: 130  RCRVGGSPRPAV 141



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 42/204 (20%), Positives = 80/204 (39%), Gaps = 11/204 (5%)

Query: 364  QDQRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            Q    +Y  +   +     ++++E K +  +   V ++     G  T   C V  +   E
Sbjct: 1414 QADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVA-QAQTE 1472

Query: 423  VTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            V W+ + +++   ++ K+ +   G    L++     + +G  +C A    G       L+
Sbjct: 1473 VMWYKDGKKL--SFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFHLH 1526

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V E + V A K       +    G    L+       T  +TW KDG  +  + ++R+  
Sbjct: 1527 VAEPKAVFA-KEQPASREVQAEAGTSATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEA 1584

Query: 542  DGGASTLDIPRAKASDAAWYQCTA 565
             G    L +  A  +DA  Y C A
Sbjct: 1585 VGCTRRLVVQEAGQADAGEYSCKA 1608



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            A +F R L  +    G  V L C L P       V W C    ++ G RF+   E    +
Sbjct: 1808 AAKFCRLLEPVCGELGGTVTLACELSPA---CAEVVWRCGNTQLRVGKRFQMVAEGPVRS 1864

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            L +L +  ED+G Y C++ +    A  + ++  + K
Sbjct: 1865 LTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVK 1900



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 13/122 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P KF   +++    E       C +  K  P   +EW++  + L  G R+    D     
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELS-KMAP---VEWWKGHETLRDGDRHSLRQDGARCE 3680

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  + AED+GEY+C      G++ T A ++ + +P   ++     G++  EA     A
Sbjct: 3681 LQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE-----GLRNEEATEGDTA 3731

Query: 3949 TI 3950
            T+
Sbjct: 3732 TL 3733



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 11/119 (9%)

Query: 1300 QVREDITV-MQAPQ--FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            Q R   T+ ++APQ  F   L +++  EG+   L+C L    + T  V W   G  ++  
Sbjct: 3876 QERTSATLTVRAPQPVFREPLQSLQAEEGSTATLQCELS---EPTATVVWSKGGLQLQAN 3932

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL-ESQH 1414
             R  P  +     L L  +  ED+G YTC      G   TS  L V A     L E QH
Sbjct: 3933 GRREPRLQGCTAELVLQDLQREDTGEYTCTC----GSQATSATLTVTAAPVRFLRELQH 3987



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTL 4571
            P F+ T  +     G  +RL+  V     +   WLK+G ++  D R+  +++  DGT +L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT-DGRHHHIDQLGDGTCSL 4956

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            LI      D+G Y C   N  G+    A  VVS
Sbjct: 4957 LITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGF 3752
            PP F  E+ D      G  V   CRV   G P   I W+ +G+          + D  G 
Sbjct: 6013 PPDFEEELAD-CTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGS 6069

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             AL +D +   D+G+Y C A +  G+ +T  KI
Sbjct: 6070 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKI 6102



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R   A  M  L +      D+G Y+C A    G   +S  L+ V
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRLSFHLD-V 1343

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             + K    +     + ++  + G  A   C V        ++ WY +G+ +  S++++  
Sbjct: 1344 SEPKAVFAKEQLAHRKVQA-EAGAIATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRME 1399

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            +      L +      D+GEY C A
Sbjct: 1400 AVGCTRRLVVQQACQADTGEYSCEA 1424



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165
            +AR   V   L DA   EEG WA F C ++ H    V W LNG  + N S +++++ G  
Sbjct: 2554 EAREVTVTGPLQDAEATEEG-WASFSCELS-HEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611

Query: 4166 HFDIPKTRQ 4174
            H  + K+ Q
Sbjct: 2612 HTLVLKSIQ 2620



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP FV+   A    EGE A+F C + G P P++ W  +G  +  G++++
Sbjct: 6107 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
           ES +++       L    PP  A +   ++L E  +AQ   +LS +    VTW K+G+ L
Sbjct: 690 ESSIRMEVRAAPGLTANKPPAAAAREVLARLHE--EAQLLAELS-DQAAAVTWLKDGRTL 746

Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               K+E+  +     L VR+  + D+G Y
Sbjct: 747 SPGPKYEVQASAGRRVLLVRDVARDDAGLY 776



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 11/175 (6%)

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            F K  + + V E      +  +T RP+PE+ W  N   +    N +I   E   H L++ 
Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHA-EGARHRLVLH 2047

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV  +D G   C    ++ +   Q +L V E  QV   + V     +  RE     +  +
Sbjct: 2048 NVGFADRGFFGC----ETPDDKTQAKLTV-EMRQV---RLVRGLQAVEAREQGTATMEVQ 2099

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
                     +W +DG+     P   +   G   TL +   +  D+      A+ V
Sbjct: 2100 LSHADVDG-SWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGV 2153



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371
            +F  AL ++E +EG    L C L  V      V+W      ++ G ++    E   + L 
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELV 3242

Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            + ++ P+DSG Y+C      G+  TS  L V A
Sbjct: 3243 VRNLRPQDSGRYSC----SFGDQTTSATLTVTA 3271



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
            +P F  PLQ L + +EG  A  + +L   S+PT  V W K G  + A+ R          
Sbjct: 3889 QPVFREPLQSL-QAEEGSTATLQCEL---SEPTATVVWSKGGLQLQANGRREPRLQGCTA 3944

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             L +  L+ ED G YT    ++   A  T +
Sbjct: 3945 ELVLQDLQREDTGEYTCTCGSQATSATLTVT 3975



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            Q  +A+ K   +++    Q+R  + + V + P F  +L   T    G++    CR+   P
Sbjct: 5985 QARTAIIKSSWVKEICGIQQR--LALPVWRPPDFEEELADCTA-ELGETVKLACRVTGTP 6041

Query: 1873 DPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             P   + WY +GK +Q   H     +  G  AL + ++ G DSG+Y C A +  G   + 
Sbjct: 6042 KPV--ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTL 6099

Query: 1932 IRLNVQ 1937
             ++ VQ
Sbjct: 6100 GKILVQ 6105



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 77/397 (19%), Positives = 149/397 (37%), Gaps = 37/397 (9%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            E  +K +      + ++     E  +A FE +     +    W  ++ P+  S + ++  
Sbjct: 4331 EAQLKVTAKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVF 4390

Query: 4462 FST--KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            F    + +L+++ +  +DS     +A    G    SA L V   R +    I+ P     
Sbjct: 4391 FENGLRHLLLLKNLRPQDSCRVTFLA----GDMVTSAFLTVRGWRLE----ILEP----- 4437

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGT-YTLLILEAY 4577
             +N  V +G        ++   P+ +  W  NG  VQPD  +  +  DG+ + LL+  A 
Sbjct: 4438 LKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQ 4497

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
            P  +G+      ++   AR     V+ LP   D P+     A +   +        +++G
Sbjct: 4498 PHHAGEVTFACRDAVASARL---TVLGLP---DPPEDAEVVARSSHTVTLSWAAP-MSDG 4550

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIK-PSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
                   ++  K   T QW    +L+  P          + Y  R++   P   G+    
Sbjct: 4551 GGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGE---- 4606

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
              +    V +A   K   P      P+    R +    G+    + ++ ++    I W +
Sbjct: 4607 PVHLPQTVRLAEPPKPVPPQ-----PSAPESRQVAA--GEDVSLELEVVAEAGEVI-WHK 4658

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                I     F+++ +G   +L+I     ED G + C
Sbjct: 4659 GMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 11/151 (7%)

Query: 4585 ECVAINSA-GEA-RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL----KDKIVAEGQ 4638
            ECV    A GE  R     V  + A +    PQT     PP+ + P     + + VA G+
Sbjct: 4580 ECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGE 4639

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC-VA 4697
             +    ++V +    + W+KG + I+P   F++     +  L I     ED+G+Y C +A
Sbjct: 4640 DVSLELEVVAEAGEVI-WHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLA 4698

Query: 4698 YNS--AGRVTVAAKLKVTQPDQADNLPALTP 4726
              S      T    L     D+A   P+L P
Sbjct: 4699 QGSICPAAATFQVALSPASVDEAPQ-PSLPP 4728



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/151 (23%), Positives = 51/151 (33%), Gaps = 4/151 (2%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            V PE +     +   PVF++      V++G    F C VTG P P V W  +G  +    
Sbjct: 5111 VPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD 5170

Query: 4156 RYKLTYD--GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNA 4213
             Y +  D  G +   I      D G    +             L+V     DY       
Sbjct: 5171 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADAT 5230

Query: 4214 PRPWYDETTQY--QRTETELEKTFEERQVLQ 4242
                Y     Y   R +   E T +E Q+ Q
Sbjct: 5231 ESSSYFSAQGYLSSREQEGTESTTDEGQLPQ 5261



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            PRF+T+ ++    V  + T   CQ+  VG+P  +V W  + +P+    RF    D     
Sbjct: 10   PRFLTRPKAFVVSVGKDAT-LSCQI--VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR 66

Query: 4033 MNFGWVYPEDSGEYLCRATNLYG 4055
            +    +   DSG+Y+CRA N  G
Sbjct: 67   LTILDLALGDSGQYVCRARNAIG 89



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R         L +      D+G YSC+A    G   +S  L   
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVA 1620

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            +           H + ++  + G SA   C V        ++ WY +G+ +  S++++  
Sbjct: 1621 EPKVVFAKEQPAH-REVQA-EAGASATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRVE 1675

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            +      L +      ++GEY C A
Sbjct: 1676 AVGCTRRLVVQQAGQAEAGEYSCEA 1700



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 12/111 (10%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            ++W+ +   +  S + +      M  L IL     D+G Y C+A +     E++V     
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTV----- 2553

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++   T  +Q+ E  ++G  A F C    +   D ++EW  NG P+
Sbjct: 2554 ---EAREVTVTGPLQDAEATEEGW-ASFSC---ELSHEDEEVEWSLNGMPL 2597



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 7/97 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P   I PL+      G  +     +   G P   + WLK+ ++I  S ++  +       
Sbjct: 2826 PAAIIKPLEDQWVAPGEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAM 2882

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            L +   +++D+GEYTC   +    +++ A LHV  +A
Sbjct: 2883 LVIRGASLKDAGEYTCEVEA----SKSTASLHVEEKA 2915



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 43/172 (25%), Positives = 64/172 (37%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +T+    R           L+I G    D+G YSC      GQ   S  L   
Sbjct: 3743 VEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVC----GQERTSATLTV- 3797

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
               +    RF   ++N E  ++G +A  +C +         +EW    + +R   R    
Sbjct: 3798 ---RALPARFIEDVKNQEA-REGATAVLQCEL----SKAAPVEWRKGSETLRGGDRYSLR 3849

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             D     L I      D+GEY C      G++ T AT+       V+ E LQ
Sbjct: 3850 QDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVRAPQPVFREPLQ 3897



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 17/143 (11%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S ++ V  P+++    + E      + EG+ A F+C++        R      G  LQ+ 
Sbjct: 4240 SAQLTVRAPEVT----ILEPLQDVQLSEGQDASFQCRLSRASGQEARWAL--GGVPLQAN 4293

Query: 2289 ARFHITFDFGYVSLDIQHCVP-EDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
                IT + G + L   H V  EDAG  S      +G C+S   + VTAK +++      
Sbjct: 4294 EMNDITVEQGTLHLLTLHKVTLEDAGTVSFH----VGTCSSEAQLKVTAKNTVV------ 4343

Query: 2348 EGLEKIRELESAEPFKRPEIPEP 2370
             GLE +  LE  E     ++ +P
Sbjct: 4344 RGLENVEALEGGEALFECQLSQP 4366



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+S L+ +V +EG    F+C V PS    + + WF +   L    ++  +   +  SL I
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPS---DVAVVWFRDGALLQPSEKFAISQSGASHSLTI 1957

Query: 2836 THTYEEDSGIYTCKATNSKGSA 2857
            +    ED+G  T +A  +  SA
Sbjct: 1958 SDLVLEDAGQITVEAEGASSSA 1979



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 57/275 (20%), Positives = 105/275 (38%), Gaps = 35/275 (12%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V     + V W ++G  +QP  +  I +   +++L I +   +D+G+   + + + G + 
Sbjct: 1921 VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ---ITVEAEGASS 1977

Query: 4597 CDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
              A  V   P   K K +PQT                 V E  ++    ++  +P P ++
Sbjct: 1978 SAALRVREAPVLFKKKLEPQT-----------------VEERSSVTLEVELT-RPWPELR 2019

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            W +    + P K  ++      + L +      D G + C   +   +    AKL V   
Sbjct: 2020 WTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ----AKLTV--- 2072

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
             +   +  +  L+ +   E   A  + Q+ S       W R+G    + P   +   G  
Sbjct: 2073 -EMRQVRLVRGLQAVEAREQGTATMEVQL-SHADVDGSWTRDGLRFQQGPTCHLAVRGPM 2130

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              L +     ED+G    +A      V TSA+LVV
Sbjct: 2131 HTLTLSGLRPEDSGLMVFKAE----GVHTSARLVV 2161



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 5/70 (7%)

Query: 804  VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            V+WYKD  P++ S +           L I+ L   DAG Y  +A    G A S+  + V 
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 864  ARS-TVTADL 872
            AR  TVT  L
Sbjct: 2555 AREVTVTGPL 2564



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 32/126 (25%), Positives = 56/126 (44%), Gaps = 11/126 (8%)

Query: 2617 EQIQLKEAAMNKVPEMFVDTG----VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            + IQ  +A + +   + V T     V+  P+    LK+ D L   +   L  Q E  +DP
Sbjct: 2617 KSIQRADAGIVRASSLKVSTSARLEVRVKPV--VFLKALDDLSAEERGTLALQCEV-SDP 2673

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
               + W K+GV L    +       G   L ++ +  +D+G+YTC     +G   + A +
Sbjct: 2674 EAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARV 2729

Query: 2733 KIEDRH 2738
            ++ D H
Sbjct: 2730 RVHDLH 2735



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 11/126 (8%)

Query: 1815 ESALQKIQQLEDSSRY-----QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRI 1868
            E  LQ +Q+ ED+  Y      +     + V  AP RF+ +L    ++ EG +AH  C +
Sbjct: 3945 ELVLQDLQR-EDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQ-EVDEGGTAHLCCEL 4002

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
                     VEW      L    +Y+   D   A L +  V  ED+G+YTC   +    A
Sbjct: 4003 SR---AGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMA 4059

Query: 1929 VSSIRL 1934
              S+R+
Sbjct: 4060 SLSVRV 4065



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 35/166 (21%), Positives = 63/166 (37%), Gaps = 10/166 (6%)

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            +Y   T  ++T   + ++E  +    V+   D +VT  +   F C V+      V W + 
Sbjct: 4138 EYACVTGGQKTAASLRVTEPEVT--IVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQ 4195

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
               ++ +   ++ V +   H L +  VT  D+G V+       G  A   +L V   E  
Sbjct: 4196 GLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF----HLGNHASSAQLTVRAPEVT 4251

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534
            +    +E    + + EG+      R          W   GVP+  N
Sbjct: 4252 I----LEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQAN 4293



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 4/106 (3%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG-HRYRT 1895
            E+   + P F +   G T+   G +   EC +    D  +R  W  +G  L  G H +  
Sbjct: 4891 EMKQQEGPMF-SHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHID 4947

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
                G  +L I  +   D+G YTC+  N  GQ   S  + V   ES
Sbjct: 4948 QLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSES 4993



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   ++  +   + G   +   +++G P+P ++W+K+G+ +     H +I   + +   
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 325  VRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESP 358
            + ++    DSG Y   A +  G   T G + V+ P
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 16/201 (7%)

Query: 2538 PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXX 2597
            P++   W  +GVEL+ G            +L I      D G+Y+C A +          
Sbjct: 2192 PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHD---AQSSASV 2248

Query: 2598 XXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEG 2657
                    +I + +  E   +IQ    A N   E      V++ P+ T      DK+   
Sbjct: 2249 KVQGRTYTLIYRRVLAEDAGEIQF--VAEN--AESRAQLRVKELPV-TLVRPLRDKIAME 2303

Query: 2658 QH-VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            +H   LE QV   +  + ++ WFK    L  G + +   D     L I+ +  +D   YT
Sbjct: 2304 KHRGVLECQV---SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYT 2360

Query: 2717 CKATNLLGEAVSTASIKIEDR 2737
            C A    G+  ++A   +E++
Sbjct: 2361 CDA----GDVKTSAQFFVEEQ 2377



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 8/96 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P RF   +KD ++V EGG     C +  V  P   + W +       G +     +   +
Sbjct: 3184 PVRFQEALKD-LEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAML 3239

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
             L +  +  +D+G Y+C     +G  TT+A +T +A
Sbjct: 3240 ELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTA 3271



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 7/87 (8%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            +LK++E+ EG  A    R + +S     V+W + N  L+ G +++       + L + + 
Sbjct: 3190 ALKDLEVLEGGAATL--RCV-LSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNL 3246

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIV 1669
             P+DSG Y+C    + G+  TS    V
Sbjct: 3247 RPQDSGRYSC----SFGDQTTSATLTV 3269



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 6/109 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P K  +  RN +  EGA A  + +LS      V W+K  + L + ++H +        L+
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELS--KMAPVEWWKGHETLRDGDRHSLRQDGARCELQ 3682

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            +R     D+G Y  +     G   TS  L V +    +++  R++  T+
Sbjct: 3683 IRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLRNEEATE 3727



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 9/124 (7%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P KFI  +++    E +     C +  K  P   +EW +  + L  G R+    D     
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS-KAAP---VEWRKGHETLRDGDRHSLRQDGSRCE 3768

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  +   D+GEY C      G++ T AT++ + LP   +++ V     R  A   ++ 
Sbjct: 3769 LQIRGLAVVDAGEYSCVC----GQERTSATLTVRALPARFIED-VKNQEAREGATAVLQC 3823

Query: 3949 TIKK 3952
             + K
Sbjct: 3824 ELSK 3827



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 7/121 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L N    EGD     C +  +      +EW   ++ L  G R+    D S   L I
Sbjct: 3716 FIEGLRNEEATEGDTATLWCELSKAAP----VEWRKGHETLRDGDRHSLRQDGSRCELQI 3771

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                  D+G Y+C     + SAT   ++R    + I  D ++ + + G  AV Q E ++ 
Sbjct: 3772 RGLAVVDAGEYSCVCGQERTSATL--TVRALPARFIE-DVKNQEAREGATAVLQCELSKA 3828

Query: 2896 A 2896
            A
Sbjct: 3829 A 3829



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 10/116 (8%)

Query: 1831 QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Q R    + V   P RFI  +    +  EG +A  +C +         VEW    + L+ 
Sbjct: 3788 QERTSATLTVRALPARFIEDVKNQ-EAREGATAVLQCELSKAAP----VEWRKGSETLRG 3842

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
            G RY    D     L I  +   D+GEY+C      GQ  +S  L V++ + + R+
Sbjct: 3843 GDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVRAPQPVFRE 3894



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 38/146 (26%), Positives = 59/146 (40%), Gaps = 12/146 (8%)

Query: 1385 CQATNQLGEAVTSCA---LRVIAKKDLILESQHPSGLEKIQYLEDTSRY---KKTDIIDE 1438
            C+ +    E V  C    LRV  +  ++ E    S        ED   Y    + D    
Sbjct: 1830 CELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSA 1889

Query: 1439 SVTIK-PRFVTRPKSIENVI--EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
             +T+  PR V     +  V+  EG    F+C + P   S++ V WF++G  +    +F  
Sbjct: 1890 QLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAI 1946

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRA 1521
                   +L I DL+ ED+G  T  A
Sbjct: 1947 SQSGASHSLTISDLVLEDAGQITVEA 1972



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 76/330 (23%), Positives = 129/330 (39%), Gaps = 41/330 (12%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P  F+  +   + EE   +  +C V    DP+  + W ++G  L    +Y  ++  G   
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCEVS---DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG 2702

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L +  V  ED+G Y C      G + T+A +   ++ D  L   + + +K  E L     
Sbjct: 2703 LVVHDVSPEDAGLYTCHV----GSEETRARV---RVHD--LHVGITKRLKTMEVLEGESC 2753

Query: 3949 TIKKYTSEVYLTEDDLYDVDKK---QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNM 4005
            + +   S    ++  ++ V  K      RF    Q +  ++ +     E   +  G+   
Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVR----EAAPSDAGEVVF 2809

Query: 4006 KVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCR----ATNLYGMDETKA 4061
             V    +   L+ + R   I       +   WV P +  E  C      T ++ + + KA
Sbjct: 2810 SVRGLTSKASLIVRERPAAIIK----PLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKA 2865

Query: 4062 VIKTTGKPGIVYDSQLP------KHMKSI-EKIREMEASWQVTPEQVVEESKARCPPVFV 4114
            + K+  K  +V +  +         +K   E   E+EAS + T    VEE KA C   F 
Sbjct: 2866 IRKSQ-KYDVVCEGTMAMLVIRGASLKDAGEYTCEVEAS-KSTASLHVEE-KANC---FT 2919

Query: 4115 SLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
                 + VEE   A F C+ T HP   V W
Sbjct: 2920 EELTNLQVEEKGTAVFTCK-TEHPAATVTW 2948



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 8/110 (7%)

Query: 1974 VVEKPQ-FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V EKP  F + + +A +TEG  + L    +  + P   V W  +G+ ++   R + +++ 
Sbjct: 3091 VTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP---VCWTKDGKTLRGSARCQLSHEG 3147

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082
                L I  A  +D+G Y C+A    G A ++S V+V A+   + + L +
Sbjct: 3148 HRAQLLITGATLQDSGRYKCEA----GGACSSSIVRVHARPVRFQEALKD 3193



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            I + P +FI  +K+    E      +C +         +EW +  + L  G RY    D 
Sbjct: 3533 IRALPARFIEDVKNQEAREGATAVLQCELNSAAP----VEWRKGSETLRDGDRYSLRQDG 3588

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+GEY C      G++ T A ++ + LP
Sbjct: 3589 TKCELQIRGLAMADTGEYSCVC----GQERTSAMLTVRALP 3625



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 9/124 (7%)

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            Q R    + V   P   T+     + +EG +A   C +         VEW+   + L+ G
Sbjct: 3612 QERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDG 3667

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES-IIRDSQHE 1949
             R+    D     L I  +  ED+GEY C      G+  +S  L V++  S  I   ++E
Sbjct: 3668 DRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLRNE 3723

Query: 1950 SALE 1953
             A E
Sbjct: 3724 EATE 3727



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 9/101 (8%)

Query: 1454 ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAED 1513
            E   EG      C+L  +      VEW+K  + +  G R     D     L I  L+AED
Sbjct: 3635 EEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAED 3690

Query: 1514 SGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLE 1553
            +G Y C    + G +  S  LT R+  +  +   +NE   E
Sbjct: 3691 AGEYLC----MCGKERTSAMLTVRAMPSKFIEGLRNEEATE 3727



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++          L +     TD+G YSC A    GQ  +S +L   
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEAR---GQ-RVSFRLHIT 1068

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            +         + H  N    + G SA   C V        ++ WY +G+ +  S+++   
Sbjct: 1069 EPKMMFAKEQSVH--NEVQAEAGASAMLSCEVA---QAQTEVTWYKDGKKLSSSSKVGME 1123

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
                   L +      D+GEY C A
Sbjct: 1124 VKGCTRRLVLPQAGKADAGEYSCEA 1148



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P  F++  K+    +GG A     L     PV  W      L   +KYS+R  ++   + 
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGDKYSLR--QEGAMLE 3240

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163
            L+++ + P D G Y+C+  +Q   A  +V   P
Sbjct: 3241 LVVRNLRPQDSGRYSCSFGDQTTSATLTVTALP 3273



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 8/97 (8%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P  FI +++     E       C +  K  P   +EW +  + L  G R+    D     
Sbjct: 3361 PAHFIGRLRHQESIEGATATLRCELS-KAAP---VEWRKGRESLRDGDRHSLRQDGAVCE 3416

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L I  +   D+GEY C      GE+ T AT++ K LP
Sbjct: 3417 LQICGLAVADAGEYSCVC----GEERTSATLTVKALP 3449



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 38/172 (22%), Positives = 67/172 (38%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +T+    R           L+I G    D+G YSC    +   A ++V+   +
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPI 3626

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                    +FT  ++N E   +G +A   C +  +      +EW+   + +R   R    
Sbjct: 3627 --------KFTEGLRNEEAT-EGATAVLRCELSKM----APVEWWKGHETLRDGDRHSLR 3673

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             D     L I      D+GEY+C      G++ T A +        ++E L+
Sbjct: 3674 QDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLR 3721



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 9/108 (8%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV   P +F+  L N E  EG    L C L  +      VEW+   + ++ G R     
Sbjct: 3619 LTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQ 3674

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILE 1411
            +     L +  +  ED+G Y C      G+  TS  L V A     +E
Sbjct: 3675 DGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE 3718



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 8/94 (8%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P +FI  +K+    E      +C +  K  P   +EW +  + L  G RY    D     
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCELS-KAAP---VEWRKGSETLRGGDRYSLRQDGTRCE 3856

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            L I  +   D+GEY C      G++ T AT++ +
Sbjct: 3857 LQIHGLSVADTGEYSCVC----GQERTSATLTVR 3886



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 60/272 (22%), Positives = 105/272 (38%), Gaps = 29/272 (10%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F +  ++ +  +G  A  + +L   PT  V W++    L    +   R    T +  L
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAE--L 3946

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            +++ +   D GEYTCT  +Q   A  +V   P               ++ V E       
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLTVTAAP-------VRFLRELQHQEVDEG------ 3993

Query: 192  GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE--SD 249
            GT     E SR    V +  G    S   F     +Y+++++ +  E + +    E   D
Sbjct: 3994 GTAHLCCELSRAGASVEWRKG----SLQLF--PCAKYQMVQDGAAAELLVRGVEQEDAGD 4047

Query: 250  VQISTEIDRSLGPVS----PPKIAQKPRNSKLQEGADAQFQVQLS-GNPRPRVTWFKNGQ 304
                T   +S+  +S     PK   + ++ + + G  A+   QLS       V W K G 
Sbjct: 4048 YTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGV 4107

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L    K+E+ +      L +   +  D+G Y
Sbjct: 4108 ELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 6/108 (5%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G   T  TLT  A    P  F        + E  +AH  C L     S   VEW      
Sbjct: 3964 GSQATSATLTVTAA---PVRFLRELQHQEVDEGGTAHLCCELSRAGAS---VEWRKGSLQ 4017

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
            L   ++ + + D     L + GV Q DAG YTC   +    A++S ++
Sbjct: 4018 LFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP F       T E GE  +  CRVTG PKP + W  +G  +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAV 6054



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/56 (32%), Positives = 28/56 (50%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            VG+P+ +  W  +   +  G+RFR   D     L I  +   D+G Y+C+A N  G
Sbjct: 34   VGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIG 89



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 7/122 (5%)

Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
           VGE  V     +       +  ++A+  R  + + GA A    +++   +  VTW+K+G+
Sbjct: 872 VGEDSVDFRLRVSEPKVVFAKEQLAR--RKLQAEAGASATLSCEVA-QAQTEVTWYKDGK 928

Query: 305 RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           +L +S+K  +  T     L V+   ++D+G Y+  A    G    S +L V+ P   + +
Sbjct: 929 KLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA----GGQRLSFHLDVKEPKVVFAK 984

Query: 365 DQ 366
           DQ
Sbjct: 985 DQ 986



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 58/241 (24%), Positives = 96/241 (39%), Gaps = 21/241 (8%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVS-LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            V+W +    L   +K  M   E  G    L++++ G  D GEY+C A +Q       V  
Sbjct: 1565 VTWYKDGKKLSSSSKVRM---EAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHV-A 1620

Query: 162  QPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF 221
            +P+              +R V    E  A  T      Q+ QT+   Y +G   SS+   
Sbjct: 1621 EPK-----VVFAKEQPAHREVQ--AEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKV 1672

Query: 222  KVDTF--EYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKP-RNSKL- 277
            +V+      RL+ + + +    +        Q+S  +  +      P+I+++P R   L 
Sbjct: 1673 RVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVA---ELEPQISERPCRREPLV 1729

Query: 278  -QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             +E  D      L+      VTW K+G  +  S +HE  +  +  TL V   Q  DS  Y
Sbjct: 1730 VKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIY 1789

Query: 337  T 337
            +
Sbjct: 1790 S 1790



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 45/172 (26%), Positives = 72/172 (41%), Gaps = 13/172 (7%)

Query: 2245 VTELRGTTHVFEGKTAHFECQV--EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
            +T+   T  V EG++  FEC +  E   DP +   +   GK + S++RF  T       L
Sbjct: 2738 ITKRLKTMEVLEGESCSFECVLSHESASDPAM---WTVGGKTVGSSSRFQATRQGRKYIL 2794

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPF 2362
             ++   P DAGE  V ++  L   TS  S+ V  + + I +    + +    ++E     
Sbjct: 2795 VVREAAPSDAGEV-VFSVRGL---TSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL 2850

Query: 2363 KRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCR---LIPVGDPTLKVE 2411
             R   P    + R    +  Q  D + EG  A    R   L   G+ T +VE
Sbjct: 2851 SRAGTPVHWLKDRKAIRKS-QKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 7/90 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KD+ V E  AA     L  V  P   V+W      +   ++ +   +   + L +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVV 3243

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            + + P+DSG Y+C      G+  TS+TL V
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTV 3269



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + + P +FI ++++    E       C +  K  P   +EW +  + L  G RY    D 
Sbjct: 3269 VTALPAQFIGKLRNKEATEGATATLRCELS-KAAP---VEWRKGSETLRDGDRYCLRQDG 3324

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+ EY C      GE+ T A+++ + +P
Sbjct: 3325 AMCELQIRGLAMVDAAEYSCVC----GEERTSASLTIRPMP 3361



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            K  ++  E ++   P F+    D  +   G  +  +C V    D  +R  W  +G     
Sbjct: 4884 KGYKVRKEMKQQEGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVELTD 4940

Query: 3741 GSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            G   H   L D G  +L I  +   DAG YTC+ +NK+G  T +A +  S
Sbjct: 4941 GRHHHIDQLGD-GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS--NRLTTMHDFG 1766
            + P+F+    D       A   E  +    D  +R  WL++GV +     + +  + D G
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD-G 4952

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
              +L +  ++  D+G YTC+  N+ G+ VT S   V S +  + ES
Sbjct: 4953 TCSLLITGLDRADAGCYTCQVSNKFGQ-VTHSACVVVSGSESEAES 4997



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 6/125 (4%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK-NGQRLI-----NSNKHEIITTH 318
            PP++ ++    K+++G+   F V++ G P P V W +   +R +     ++  + + ++ 
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 319  NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378
               +L + +  +   G YT +A N  G  + S  L V    +   Q++  + +  T  + 
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQG 5489

Query: 379  TEERI 383
            T + I
Sbjct: 5490 TTQAI 5494



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 12/117 (10%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI- 694
            PP+ +         +G  I F  ++E  G P   + WL+  +  E    +      GY  
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVE--GRPVPTVHWLR--EEAERGVLWIGPDTPGYTV 5425

Query: 695  -------SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
                   SL +L +  Q  G YTC A +A G A   A LHV+    +E   +  E L
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEAL 5482



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/90 (25%), Positives = 40/90 (44%)

Query: 4724 LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNT 4783
            LT  +  VV  G+ A    QI     P + W ++   +     F++  +G+   L I + 
Sbjct: 13   LTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDL 72

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               D+G + CRA  A G+   +  L V ++
Sbjct: 73   ALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 49/215 (22%), Positives = 84/215 (39%), Gaps = 18/215 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P  F+  ++D +   E   V  +C +     P + + W  +G     G  +         
Sbjct: 2165 PVSFSRPLQDVVTT-EKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACR 2220

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEK--IKEL 3811
            +L I      D G Y C A +    A ++A +    +   ++  ++    +GE   + E 
Sbjct: 2221 SLTIYRCEFADQGVYVCDAHD----AQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAEN 2276

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
               R     KE P+    P    +I    +E+  GV  EC+V        ++ W++  + 
Sbjct: 2277 AESRAQLRVKELPVTLVRP-LRDKI---AMEKHRGV-LECQVSRAS---AQVRWFKGSQE 2328

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906
            L  G +Y  V D  +  L I  V+AED   Y C A
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 47/224 (20%), Positives = 82/224 (36%), Gaps = 29/224 (12%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RP  F    KD+ ++ EG  A     L      +  ++W Y    +    +        M
Sbjct: 3183 RPVRFQEALKDL-EVLEGGAATLRCVL---SSVAAPVKWCYGNNVLRPGDKYSLRQEGAM 3238

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            + L +   +  DSG YSC   ++   A ++V             +F   ++N E   +G 
Sbjct: 3239 LELVVRNLRPQDSGRYSCSFGDQTTSATLTVT--------ALPAQFIGKLRNKEAT-EGA 3289

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A   C +         +EW    + +R   R     D     L I      D+ EY C 
Sbjct: 3290 TATLRCELSKA----APVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCV 3345

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269
                 GE+ T A++         +  +    + ++R  ES++GA
Sbjct: 3346 C----GEERTSASLT--------IRPMPAHFIGRLRHQESIEGA 3377



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PKF T+++S   E  +  R  C++   E   + ++W + G  L +G +Y          L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAV-VQWLKEGVELHAGPKYEMRSQGATREL 4126

Query: 3890 DILYVYAEDSGEYIC 3904
             I  + A+D+GEY C
Sbjct: 4127 LIHQLEAKDTGEYAC 4141



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFGYVA 2036
            P F + + +     G  V L   +T    P   + WY +G+ VQ   H        G  A
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +      D+G YMC A +A G   T   + V
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 9/115 (7%)

Query: 1825 EDSSRY--QRREDVEVA--VNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRV 1878
            ED+  Y  + R+D   A      PR +  ++G + +   EG  A ++C + P    ++ V
Sbjct: 1873 EDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP---SDVAV 1929

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             W+ +G +LQ   ++  S      +L I  +  ED+G+ T +A      A   +R
Sbjct: 1930 VWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P  F+  L  ++A E G +  +     V DP   + W K+G  +  S ++  +   G   
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG 2702

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +  ++ +D+G YTC      G  ET+A + V
Sbjct: 2703 LVVHDVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 7/123 (5%)

Query: 1831 QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Q R    + +   P RFI  +    +  EG +A  +C +         VEW    + L+ 
Sbjct: 3524 QERTSATLTIRALPARFIEDVKNQ-EAREGATAVLQCELNSAAP----VEWRKGSETLRD 3578

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR-LNVQSKESIIRDSQH 1948
            G RY    D     L I  +   D+GEY+C        A+ ++R L ++  E +  +   
Sbjct: 3579 GDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEAT 3638

Query: 1949 ESA 1951
            E A
Sbjct: 3639 EGA 3641



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 1581 TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIM 1640
            T  L+N E  EG  A     L  ++     VEW+  ++ L+ G R +   +     L I 
Sbjct: 3629 TEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQIR 3684

Query: 1641 SCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE 1678
              + ED+G Y C      G+  TS +  V +  S ++E
Sbjct: 3685 GLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE 3718



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            RP F T L SLE  + GD A   C++    +    + W   G ++ AG +Y         
Sbjct: 4067 RPKFKTRLQSLEQ-ETGDIARLCCQLSDA-ESGAVVQWLKEGVELHAGPKYEMRSQGATR 4124

Query: 2168 ALDILYTYAEDSGTYMC 2184
             L I    A+D+G Y C
Sbjct: 4125 ELLIHQLEAKDTGEYAC 4141



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 49/191 (25%), Positives = 77/191 (40%), Gaps = 21/191 (10%)

Query: 1678 ESQHEGALPRL--NQLE--DTSKY------QRHSAQDEVITQAPVFTMPMKDIRVAENQA 1727
            E + +GA   L  +QLE  DT +Y      Q+ +A   V          + D  V  ++ 
Sbjct: 4116 EMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADED 4175

Query: 1728 AHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT--TMHDFGYVALNMKYVNPEDSGTYTC 1785
              F   +   G     V+W   G+P++ SN +T   + D     L +K V PED+GT + 
Sbjct: 4176 VEFSCEVSRAG--ATGVQWCLQGLPLQ-SNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF 4232

Query: 1786 RAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEV--AVNQA 1843
                 LG   +S+ L V++     LE   +  L + Q      R  R    E   A+   
Sbjct: 4233 ----HLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGV 4288

Query: 1844 PRFITQLNGPT 1854
            P    ++N  T
Sbjct: 4289 PLQANEMNDIT 4299



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 6/112 (5%)

Query: 753  YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
            +  Y+ ++ +++Q  + P F     D  E Q G     E  +   +D  +R  W KDG  
Sbjct: 4883 FKGYKVRKEMKQQ--EGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVE 4937

Query: 813  IT-ASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            +T            G  SL I  L   DAG YT +  NK G+   +A + V+
Sbjct: 4938 LTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 10/137 (7%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYDFGY 2034
            E P F     + E   G  + LE  +    D  +R  W  +G  +  G H        G 
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGT 4953

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGE-------AVTTSSVKVDAKSGLYLDTLDEQRLKK 2087
             +L I      D G Y C+ +N  G+        V+ S  + ++ SG  LD    +  ++
Sbjct: 4954 CSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARR 5013

Query: 2088 IQELEKYERPKPIEEEQ 2104
            +  L + + P  + +E+
Sbjct: 5014 LHRLFRTKSPAEVSDEE 5030



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 1/58 (1%)

Query: 928 HFEARL-EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTC 984
           H EA+L   + D    V WLKDGR +    +     + G   L ++ V   DAG Y C
Sbjct: 721 HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 30/145 (20%), Positives = 59/145 (40%), Gaps = 11/145 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W      +    R + V    +  L +LG +  D+G Y C + +    A+++V +  V
Sbjct: 1839 VVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRV 1898

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             K       F + +  +   ++G  A F+C V P    D+ + W+ +G  ++ S +    
Sbjct: 1899 VK-------FMSGLSTVVA-EEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAIS 1947

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
                   L I+     D+G+    A
Sbjct: 1948 QSGASHSLTISDLVLEDAGQITVEA 1972



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 9/130 (6%)

Query: 448  HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            H L ++ +   DSG++  V + +   T+   RL V E    +   F      +   E E 
Sbjct: 2131 HTLTLSGLRPEDSGLM--VFKAEGVHTS--ARLVVTE----LPVSFSRPLQDVVTTEKEK 2182

Query: 508  VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            V L    +  P   + W KDGV +     + I   G   +L I R + +D   Y C A +
Sbjct: 2183 VTLECE-LSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHD 2241

Query: 568  VAGSTATRAR 577
               S + + +
Sbjct: 2242 AQSSASVKVQ 2251



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 43/206 (20%), Positives = 79/206 (38%), Gaps = 14/206 (6%)

Query: 370  YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE-VTWFIN 428
            Y       ET  R+ + +  L     K  +  +V EG+   F+C ++     +   W + 
Sbjct: 2716 YTCHVGSEETRARVRVHD--LHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVG 2773

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
             + +      +    +   + L++     SD+G V    R  + + +    L V E+   
Sbjct: 2774 GKTVGSSSRFQA-TRQGRKYILVVREAAPSDAGEVVFSVRGLTSKAS----LIVRERPAA 2828

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            +     +++    V  GE V L        TP + W KD   I  + +  +  +G  + L
Sbjct: 2829 IIKPLEDQW----VAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAML 2883

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTAT 574
             I  A   DA  Y C  +  + STA+
Sbjct: 2884 VIRGASLKDAGEYTCEVE-ASKSTAS 2908



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 5/92 (5%)

Query: 2108 RPV-FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            RPV F  AL  LE L EG  A   C +  +  P   + W +    +R G +Y    +   
Sbjct: 3183 RPVRFQEALKDLEVL-EGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAM 3238

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            + L +     +DSG Y C   ++   A  T T
Sbjct: 3239 LELVVRNLRPQDSGRYSCSFGDQTTSATLTVT 3270



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 6/109 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P +  +  +N + +EGA A  Q +L  N    V W K  + L + +++ +        L+
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQ 3594

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            +R    +D+G Y+ +     G   TS  L V +    + +  R++  T+
Sbjct: 3595 IRGLAMADTGEYSCVC----GQERTSAMLTVRALPIKFTEGLRNEEATE 3639



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 11/102 (10%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG--- 1911
            +LSEGQ A ++CR+        R  W   G  LQ+      + + G   L +LT++    
Sbjct: 4260 QLSEGQDASFQCRLSRASGQEAR--WALGGVPLQANEMNDITVEQG--TLHLLTLHKVTL 4315

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            ED+G  +     ++G   S  +L V +K +++R  ++  ALE
Sbjct: 4316 EDAGTVSF----HVGTCSSEAQLKVTAKNTVVRGLENVEALE 4353



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/105 (24%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            VPP  +   ++  V +G+ V L+ +V      +V W K  +++QP  R +++ + G   +
Sbjct: 4623 VPPQPS-APESRQVAAGEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQ-GRQQM 4679

Query: 4572 LILEAY-PQDSGKYEC-VAINSAGEARCDAECVVSLPATKDKPKP 4614
            L+++ +  +D G+Y C +A  S   A    +  +S  +  + P+P
Sbjct: 4680 LVIKGFTAEDQGEYHCGLAQGSICPAAATFQVALSPASVDEAPQP 4724



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG-HRYRTVYDMGFVS 3888
            P F         +  + +R EC V  K D  +R  W ++G  L  G H +      G  S
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCS 4955

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L I  +   D+G Y C+  N FG+
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQ 4979



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/86 (25%), Positives = 43/86 (50%), Gaps = 1/86 (1%)

Query: 4727 LRDIVVYEG-QPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
            LRD+ V  G + A+F+ ++     P + W ++G  +  +   +M  +     L I +   
Sbjct: 5266 LRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTR 5325

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            ED+G +    + A G   +SA+L+V+
Sbjct: 5326 EDSGQYAAYISNAMGAAYSSARLLVR 5351



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 10/151 (6%)

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPP--KFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            G+  E   E       D    +  VS P   KF++ + +   EE     F+C V P +  
Sbjct: 1869 GLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSD-- 1926

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             + + W+R+G LL    ++         SL I  +  ED+G+    A        + A +
Sbjct: 1927 -VAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAAL 1981

Query: 3920 SCKKLPDIILQNQVPRGM-KRSEALTQMEAT 3949
              ++ P +  +   P+ + +RS    ++E T
Sbjct: 1982 RVREAPVLFKKKLEPQTVEERSSVTLEVELT 2012



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 15/119 (12%)

Query: 751  EDYSKYQHQESIEEQTSQR-----PQFIRPLQDLGEL--QEGRNAHFEAQLTPVSDPTMR 803
            ED  +Y   ES ++ TS +     P+ ++ +  L  +  +EG  A F+  ++P SD  + 
Sbjct: 1873 EDAGEYVC-ESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP-SD--VA 1928

Query: 804  VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            V W++DG  +  S +     +    SL I  L  EDAG  TV A      A S+A++RV
Sbjct: 1929 VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAALRV 1983



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
            V +  P+  T  + +E K G+             A   V+WY ++ PL    +F  +   
Sbjct: 2463 VVSDIPVVLT--RPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEG 2520

Query: 1633 GFVALDIMSCLPEDSGTYTCRAINA 1657
                L I+  +P D+G Y C+A +A
Sbjct: 2521 QMAELRILRLMPADAGVYRCQAGSA 2545



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 772  FIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLN 831
            F++ L DL   + G  A  + +   VSDP   V W KDG  +  S +   +   G   L 
Sbjct: 2649 FLKALDDLSAEERGTLA-LQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV 2704

Query: 832  IMHLRAEDAGSYT 844
            +  +  EDAG YT
Sbjct: 2705 VHDVSPEDAGLYT 2717



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 8/119 (6%)

Query: 2883 GLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPD 2942
            GL  V+ AE + +    R S   T  P P   I      + +EG    L  ++  K  P 
Sbjct: 3333 GLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELS-KAAP- 3390

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
              +EW    + L  G R  L  D     L +  +   D+G Y+C      GE  TS+T+
Sbjct: 3391 --VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVC----GEERTSATL 3443



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 9/101 (8%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV   P +F+  L N E VEG    L C L  V      VEW    + ++ G R+    
Sbjct: 3443 LTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAP----VEWRKGPENLRDGDRYILRQ 3498

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            E     L +  +   D+G Y C      G+  TS  L + A
Sbjct: 3499 EGTRCELQICGLAMADAGEYLCVC----GQERTSATLTIRA 3535



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 2373 RQRPV-FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431
            R  P+ FT+ L+N +   EG TA   C L  +      VEW++  + + D  R +   D 
Sbjct: 3622 RALPIKFTEGLRN-EEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDG 3676

Query: 2432 GYVSMTISHVRDEDEGVYMC 2451
                + I  +  ED G Y+C
Sbjct: 3677 ARCELQIRGLVAEDAGEYLC 3696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
            +F + ++N E TEG    L   L+ +      VEW+     ++ G R     D     L 
Sbjct: 3627 KFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQ 3682

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL 2080
            I    AED G Y+C      G+  T++ + V A    +++ L
Sbjct: 3683 IRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGL 3720



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 90/376 (23%), Positives = 143/376 (38%), Gaps = 34/376 (9%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV  AP +F R L + E  EG   HL C L   G     VEW      +    +++   
Sbjct: 3972 LTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAG---ASVEWRKGSLQLFPCAKYQMVQ 4028

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK-DLILES--QHPSGLEK 1420
            +     L +  V  ED+G YTC   +   +++ S ++RV   K    L+S  Q    + +
Sbjct: 4029 DGAAAELLVRGVEQEDAGDYTCDTGHT--QSMASLSVRVPRPKFKTRLQSLEQETGDIAR 4086

Query: 1421 I-QYLEDTSRYKKTDIIDESVTIK--PRFVTRPKSI--ENVIEGQHVHFECKLEPVTDSN 1475
            +   L D         + E V +   P++  R +    E +I         +   VT   
Sbjct: 4087 LCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQ 4146

Query: 1476 LKVEWFKNGQP-VTIGHRFRPIHDFGYVALDIIDLIAEDS-----GIYTC-RAVNLVGTD 1528
                  +  +P VTI    R + D    A + ++   E S     G+  C + + L   +
Sbjct: 4147 KTAASLRVTEPEVTI---VRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNE 4203

Query: 1529 --EVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKN 1586
              EV+ R     T  +   T  +AG     +    S    T    EVT   P     L++
Sbjct: 4204 VTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEP-----LQD 4258

Query: 1587 VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV-ALDIMSCLPE 1645
            V++ EGQ A F+ RL   S    +  W     PL++      T   G +  L +     E
Sbjct: 4259 VQLSEGQDASFQCRLSRASGQ--EARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLE 4316

Query: 1646 DSGTYTCRAINALGEA 1661
            D+GT +        EA
Sbjct: 4317 DAGTVSFHVGTCSSEA 4332



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 13/134 (9%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            +++   VF + L++   ++EG+++ L C       P   V W  +G+++   +R +  ++
Sbjct: 3091 VTEKPSVFSRELTDAT-ITEGEDLTLVCETSTCDIP---VCWTKDGKTLRGSARCQLSHE 3146

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL 1291
                 L I  AT  D+G Y   A    G A +S+IVRV  R       + ++A++ +++L
Sbjct: 3147 GHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRVHAR-----PVRFQEALKDLEVL 3197

Query: 1292 EDAARRTKQVREDI 1305
            E  A   + V   +
Sbjct: 3198 EGGAATLRCVLSSV 3211



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 8/126 (6%)

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRR-----EDVEVAVNQAPRFITQLNGP 1853
            TL   ++  L  E      L     L+DS RY+           V V+  P    +    
Sbjct: 3134 TLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
             ++ EG +A   C +     P   V+W +   VL+ G +Y    +     L +  +  +D
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQD 3250

Query: 1914 SGEYTC 1919
            SG Y+C
Sbjct: 3251 SGRYSC 3256



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W KDG+ + +SS++          L ++ V   DAG Y+C A    G    S  L I 
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSFQLHIT 1252

Query: 1003 TKKDIIAESQ 1012
              K + A+ Q
Sbjct: 1253 EPKAVFAKEQ 1262



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 2011 VEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            V+WY +  P+    +FK + +     L IL     D G Y C+A    G A +++ V V+
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 2071 AK 2072
            A+
Sbjct: 2555 AR 2556



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/140 (24%), Positives = 60/140 (42%), Gaps = 9/140 (6%)

Query: 2197 CTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256
            C L   GHR  +L T          + EA G  +   +      P RF   L+    V E
Sbjct: 3141 CQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSS-SIVRVHARPVRFQEALKDL-EVLE 3198

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            G  A   C +  V  P   +++ +    L+   ++ +  +   + L +++  P+D+G YS
Sbjct: 3199 GGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255

Query: 2317 VKAINALGHCTSAISMTVTA 2336
                 + G  T++ ++TVTA
Sbjct: 3256 C----SFGDQTTSATLTVTA 3271



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 7/97 (7%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P +F   +K   V E       C +     P   ++W     +L  G +Y    +   + 
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLE 3240

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L +  +  +DSG Y C     FG+  T AT++   LP
Sbjct: 3241 LVVRNLRPQDSGRYSC----SFGDQTTSATLTVTALP 3273



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 38/172 (22%), Positives = 68/172 (39%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +++    R        +  L+I G    D+G YSC    +   A ++V     
Sbjct: 3391 VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTV----- 3445

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
               K    +FT  ++N E + +G +A   C +  V      +EW    + +R   R    
Sbjct: 3446 ---KALPAKFTEGLRNEEAV-EGATAMLWCELSKV----APVEWRKGPENLRDGDRYILR 3497

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             +     L I      D+GEY+C      G++ T AT+        ++E ++
Sbjct: 3498 QEGTRCELQICGLAMADAGEYLCVC----GQERTSATLTIRALPARFIEDVK 3545



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 6/105 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P K  +  RN +  EG  A    +LS    P V W K  + L + ++H +    +   L+
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS-KAAP-VEWRKGHETLRDGDRHSLRQDGSRCELQ 3770

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
            +R     D+G Y+ +     G   TS  L V +    +++D ++Q
Sbjct: 3771 IRGLAVVDAGEYSCVC----GQERTSATLTVRALPARFIEDVKNQ 3811



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 6/96 (6%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG +A  +C +    +P   V W   G  LQ+  R         A L +  +  ED+GEY
Sbjct: 3903 EGSTATLQCELS---EPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            TC   +   QA S+      +    +R+ QH+   E
Sbjct: 3960 TCTCGS---QATSATLTVTAAPVRFLRELQHQEVDE 3992



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 8/119 (6%)

Query: 2087 KIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWF 2146
            KIQ   K  + +   ++Q G  P+F       E  + GD    EC V    D  +   W 
Sbjct: 4878 KIQAAFKGYKVRKEMKQQEG--PMFSHTFGDTE-AQVGDALRLECVVASKAD--VRARWL 4932

Query: 2147 HNGQKIRAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKATNKLGEAVNTCTLKVAG 2203
             +G ++  G R+      G     +L T  +  D+G Y C+ +NK G+  ++  + V+G
Sbjct: 4933 KDGVELTDG-RHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSG 4990



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P   PP F  EL   T    G+T    C+V     P   I +Y +GKA+Q      +  D
Sbjct: 6009 PVWRPPDFEEELADCTAEL-GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIED 6065

Query: 2297 -FGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              G  +L +      D+G+Y   A +A G+C++
Sbjct: 6066 PDGSCALILDSLTGVDSGQYMCFAASAAGNCST 6098



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 3/113 (2%)

Query: 1035 EEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT 1094
            ++ + +  PRFL   K     V G+ A    ++    + T  V W  + + + +  R + 
Sbjct: 2    DQPQFSGAPRFLTRPKAFVVSV-GKDATLSCQIV--GNPTPQVSWEKDQQPVAAGARFRL 58

Query: 1095 YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIH 1147
              D     L I  +   DSG Y   ARNA GEA  +  + V+  ++    + H
Sbjct: 59   AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C +     P   V WY +GK L S  + R         L +  V   D+GEY+
Sbjct: 1181 GTTAMLSCEVA---QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            C+A    GQ V S +L++   +++    Q
Sbjct: 1238 CEA---GGQRV-SFQLHITEPKAVFAKEQ 1262



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 12/145 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  I  S R  T        L + G +  DS  YSCR   + GQ +  V++E V
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAE-GQ-DFPVQVEEV 1807

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                    +F   ++ + G + G +    C + P      ++ W      +R   R + V
Sbjct: 1808 ------AAKFCRLLEPVCG-ELGGTVTLACELSPA---CAEVVWRCGNTQLRVGKRFQMV 1857

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            ++     L +   +  D+GEYVC +
Sbjct: 1858 AEGPVRSLTVLGLRAEDAGEYVCES 1882



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 1024 EDASRY---SKRTEEEVKITQK-PRFLGPLKGTNKIV--EGQSAHFEARVEPQSDLTMTV 1077
            EDA  Y   S+      ++T   PR +  + G + +V  EG  A F+  V P SD+   V
Sbjct: 1873 EDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP-SDVA--V 1929

Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL 1129
             W+ +G  +  + +          +L I+ +  ED+G  TV A  A+  A L
Sbjct: 1930 VWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAAL 1981



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 4/62 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            ++W+K+   L+   + K + +  +  L I  L   D+G+Y C+A    G A S+  + +E
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 2736 DR 2737
             R
Sbjct: 2555 AR 2556



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF+  L+++  +E   +  +C V    DP   + W  +   L    +Y   H      L 
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEVS---DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV 2704

Query: 2835 ITHTYEEDSGIYTC 2848
            +     ED+G+YTC
Sbjct: 2705 VHDVSPEDAGLYTC 2718



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/49 (34%), Positives = 23/49 (46%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583
            V DP     W  +GV+L    ++   H  G   L ++ V   DAGLY C
Sbjct: 2670 VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC 2718



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 8/114 (7%)

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
            K T+    + KA  FT  L+N++ + E   A F  +   T+ P   V W      L+A  
Sbjct: 2904 KSTASLHVEEKANCFTEELTNLQ-VEEKGTAVFTCK---TEHPAATVTWRKGLLELRASG 2959

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            + +   +   + L IS     DS  Y C    + G+A + A + VQG+R  I+E
Sbjct: 2960 KHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLVQGRRVHIIE 3009



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 13/119 (10%)

Query: 1439 SVTIKP---RFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            S+TI+P    F+ R +  E+ IEG      C+L         VEW K  + +  G R   
Sbjct: 3354 SLTIRPMPAHFIGRLRHQES-IEGATATLRCELSKAAP----VEWRKGRESLRDGDRHSL 3408

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLE 1553
              D     L I  L   D+G Y+C    + G +  S  LT ++         +NE  +E
Sbjct: 3409 RQDGAVCELQICGLAVADAGEYSC----VCGEERTSATLTVKALPAKFTEGLRNEEAVE 3463



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + + P KF   +++    E       C +  K  P   +EW +  + L  G RY    + 
Sbjct: 3445 VKALPAKFTEGLRNEEAVEGATAMLWCELS-KVAP---VEWRKGPENLRDGDRYILRQEG 3500

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+GEY+C      G++ T AT++ + LP
Sbjct: 3501 TRCELQICGLAMADAGEYLCVC----GQERTSATLTIRALP 3537



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/90 (24%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P+F   L+S  +  EG    L+ ++   ++P   + W K G+ L    R +         
Sbjct: 3890 PVFREPLQSL-QAEEGSTATLQCEL---SEPTATVVWSKGGLQLQANGRREPRLQGCTAE 3945

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            L +  L+ +D+G YTC   +    A  T +
Sbjct: 3946 LVLQDLQREDTGEYTCTCGSQATSATLTVT 3975



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTC 4793
            G   + +  + SK     +WL++G  + +     +   G+    LLI      D G +TC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971

Query: 4794 RATTAAGQVETSAKLVV 4810
            + +   GQV  SA +VV
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 5/77 (6%)

Query: 3576 HFECRLIP-VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
            H E +L+  ++D +  V W  +G+ L  G + +     G  +L +  V + DAGLY C  
Sbjct: 721  HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC-- 778

Query: 3635 TNRHGEATVSCKLQVKG 3651
             +R G   ++ +L V+G
Sbjct: 779  VSRGGR--IAYQLSVQG 793



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 13/45 (28%), Positives = 21/45 (46%)

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
           +TW KDG  + P P+  +    G   L +      DA  Y+C ++
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSR 781



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 16/51 (31%), Positives = 26/51 (50%)

Query: 797  VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
            V+ P   V WYKDG+ +++SS++          L +  +   DAG Y+  A
Sbjct: 1190 VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 4/77 (5%)

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            +  +   V W KDG+ + +SS++          L ++     DAG YTC A    G    
Sbjct: 1282 VAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRL 1337

Query: 996  SANLTIVTKKDIIAESQ 1012
            S +L +   K + A+ Q
Sbjct: 1338 SFHLDVSEPKAVFAKEQ 1354



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 3/76 (3%)

Query: 1992 GHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYM 2051
            G  V L   L+P       V W C    ++ G RF+   +    +L +L   AED G Y+
Sbjct: 1823 GGTVTLACELSPA---CAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYV 1879

Query: 2052 CKATNAVGEAVTTSSV 2067
            C++ +    A  T SV
Sbjct: 1880 CESRDDHTSAQLTVSV 1895



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/94 (26%), Positives = 36/94 (38%), Gaps = 7/94 (7%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            KP       D +S +E G    +     + D    V W KDG  +  S +       G  
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTR 2701

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L +  V+  DAG YTC     +G   T A + +
Sbjct: 2702 GLVVHDVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 7/87 (8%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            GE+      L+    P   V W  + K+++   ++   C+    +L I     +D+GEY 
Sbjct: 2841 GEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897

Query: 3495 CRAYNNYGEAVTTASMKVQGKRNIILE 3521
            C        + +TAS+ V+ K N   E
Sbjct: 2898 CEV----EASKSTASLHVEEKANCFTE 2920



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 42/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F +  +D +V EG      C ++    P V W   +  +R    +  L  E     L++
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYS-LRQEGAMLELVV 3243

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             N+   DSG  +C      G+      L V      +  +F+ +       EG    L  
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVT----ALPAQFIGKLRNKEATEGATATLRC 3295

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
              +    P + W+K    +       +  DG    L I      DAA Y C    V G  
Sbjct: 3296 E-LSKAAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC----VCGEE 3349

Query: 573  ATRARL 578
             T A L
Sbjct: 3350 RTSASL 3355



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG      C +     P   ++W + N  L  G +Y    + + + L +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVV 3243

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
             +   +DSG Y+C    S G  TTS +L  T
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVT 3270



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P  F +  KN    +G  A  + +L  N    V W +    L + ++YS+R  +      
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLR--QDGTKCE 3592

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163
            L I+ +   D GEY+C    +   A+ +V   P
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALP 3625



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 4/83 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  + N   +EG     +C +  +      +EW   ++ L  G RY    D +   L I
Sbjct: 3804 FIEDVKNQEAREGATAVLQCELSKAAP----VEWRKGSETLRGGDRYSLRQDGTRCELQI 3859

Query: 2836 THTYEEDSGIYTCKATNSKGSAT 2858
                  D+G Y+C     + SAT
Sbjct: 3860 HGLSVADTGEYSCVCGQERTSAT 3882



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 9/102 (8%)

Query: 1690 QLEDTSKY-----QRHSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLR 1743
            Q EDT +Y      + ++    +T APV F   ++   V E   AH    L   G     
Sbjct: 3952 QREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAG---AS 4008

Query: 1744 VEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785
            VEW +  + +    +   + D     L ++ V  ED+G YTC
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC 4050



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG-HR 1358
            Q R  + V + P F   L +     G  V L CR+   G     + W+ +GK ++   H 
Sbjct: 6003 QQRLALPVWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHH 6060

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                      AL L S+   DSG Y C A +  G   T
Sbjct: 6061 ILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCST 6098



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 943  VEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+ V+     I      G  AL + S+T  D+G Y C A +A G  +T   + +
Sbjct: 6045 ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104


>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
          Length = 6620

 Score =  124 bits (300), Expect = 6e-27
 Identities = 89/325 (27%), Positives = 141/325 (43%), Gaps = 14/325 (4%)

Query: 245 VGESDVQISTEIDRSLGPVSP-PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
           +GE+   +  ++D         P    +P + +++EG++A F+ ++ G+PRP V+W K+G
Sbjct: 88  IGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDG 147

Query: 304 QRLINSNKHEIITTH--NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP--- 358
           +RL   +   +        + LR+R  +  D G Y + AENP G    +  L V+S    
Sbjct: 148 RRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD 207

Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
           T S      +  +   Q+R    R E +  +      + C    VTEGK  R  C VTG 
Sbjct: 208 TASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCT---VTEGKHARLSCYVTGE 264

Query: 419 PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
           P PE  W  + + + +   H +  +   N  L I     SD G+ TC A N  G+T +  
Sbjct: 265 PKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT-YSS 323

Query: 479 RLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
            L V+ +  V    F +R   L VRE E        V  P+    W K+   +  + +  
Sbjct: 324 VLVVVREPAV---PFKKRLQDLEVREKESATFLCE-VPQPSTEAAWFKEETRLWASAKYG 379

Query: 539 IHTDGGASTLDIPRAKASDAAWYQC 563
           I  +G    L +    A D A Y C
Sbjct: 380 IEEEGTERRLTVRNVSADDDAVYIC 404



 Score =  122 bits (293), Expect = 4e-26
 Identities = 100/341 (29%), Positives = 149/341 (43%), Gaps = 44/341 (12%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLL 4572
            P F    QN  V  G  V  D  VTG     V W K+GK ++ D    I E+  G + L+
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK-DKPKPQTKAAN----------- 4620
            I    P D G Y C+A NS G +   AE  V L +T  D     T++++           
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245

Query: 4621 ------------APPEIIEPLKDKIVAEGQAI-EFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                          P+++E L+D  VA G  + +F  K+ G P P + W+K  + +  S 
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA---- 4723
            + +M+     +TL I     ED G Y     N+ G    +A+L V  PD+ +  PA    
Sbjct: 5306 HIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVH 5365

Query: 4724 --LTPLRDI------VVYEGQPAQFKTQITSKIKPTIQWLREGA------LIPETPDFQM 4769
              L P R +       V +G    F  ++  +  PT+ WLRE A      + P+TP + +
Sbjct: 5366 EQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV 5425

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                    L++ +   +  GT+TC A+ AAGQ   SA L V
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score =  103 bits (248), Expect = 1e-20
 Identities = 92/342 (26%), Positives = 141/342 (41%), Gaps = 30/342 (8%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--TL 323
            P    + +N ++Q+G    F   ++G P P V WFK+G +L+  + H +I         L
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDG-KLLEEDDHYMINEDQQGGHQL 5184

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY--VQD--QRSQYITDT---QQ 376
             +     +D G Y  LAEN  G   T   L V+  +  Y    D  + S Y +       
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244

Query: 377  RETEERIEISEKALAPQFVKVCQDRDVTEG-KMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            RE E     +++   PQ V+  +D  V  G ++ +F  +V G P P + WF  D Q    
Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF-KDGQPLTA 5303

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI------EK---- 485
              H  + ++   H L I +VT  DSG       N  G      RL V       EK    
Sbjct: 5304 SAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASD 5363

Query: 486  --EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPII--PNPEL 537
              EQ+V P+ +ERF+   V++G  +  + +  G P P + W ++    GV  I    P  
Sbjct: 5364 VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423

Query: 538  RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             + +     +L +          Y C A N AG     A L+
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLH 5465



 Score = 98.7 bits (235), Expect = 5e-19
 Identities = 103/424 (24%), Positives = 163/424 (38%), Gaps = 31/424 (7%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            S  P F  + +   V   + A    +  G P P + W ++  P+     F++        
Sbjct: 7    SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYR 66

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I  + + DS  +   A N  G A  +  L V+ +          P F L   ++ V  
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA---PHFLLRPTSIRVRE 123

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKV-QPDIRNKILEEDGTYTLL-ILEAYPQDSGKYE 4585
            G       +V G+    V W K+G+++ +PD     +EE G  + L I  A P+D G YE
Sbjct: 124  GSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYE 183

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQT----------------KAANAPPEIIEP- 4628
              A N  G A   A  VV   A     +P T                +A  AP       
Sbjct: 184  VRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTG 243

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-YTLRISEAFP 4687
             +   V EG+    SC + G+P P   W K  +L+   +   +   A E + L+I     
Sbjct: 244  TRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ 303

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
             D G Y C A N  G+   +  + V +P     +P    L+D+ V E + A F  ++   
Sbjct: 304  SDRGLYTCTASNLVGQTYSSVLVVVREP----AVPFKKRLQDLEVREKESATFLCEVPQP 359

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
                  W +E   +  +  + +  EG    L + N   +D   + C   T  G   T A+
Sbjct: 360  -STEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE--TPEGS-RTVAE 415

Query: 4808 LVVK 4811
            L V+
Sbjct: 416  LAVQ 419



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 87/334 (26%), Positives = 132/334 (39%), Gaps = 30/334 (8%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP+F+   +   V+ GK     C++ G P P+V+W  + + +      + L  +   + L
Sbjct: 9   APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFR-LAQDGDLYRL 67

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVERFSTLNVREGEPV 508
            I ++ L DSG   C ARN  GE      L V  +      AP F+ R +++ VREG   
Sbjct: 68  TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEA 127

Query: 509 VLNARAVGTPTPRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
               R  G+P P ++W KDG  +     P +R+   G AS L I  A+  D   Y+  A+
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187

Query: 567 NVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIP 626
           N  G+ +  A L                  RP                L H++R R  + 
Sbjct: 188 NPLGAASAAAALVVDSDAADTAS-------RP---------GTSTAALLAHLQRRREAM- 230

Query: 627 PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686
              E     PP      ++ T  EG   H        G+P  +  W K+GQ +    R  
Sbjct: 231 -RAEGAPASPPS--TGTRTCTVTEGK--HARLSCYVTGEPKPETVWKKDGQLVTEGRRHV 285

Query: 687 SIFRFGY--ISLDMLSLNIQDSGEYTCRAVSATG 718
            ++        L +L     D G YTC A +  G
Sbjct: 286 -VYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 55/194 (28%), Positives = 87/194 (44%), Gaps = 8/194 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTL 4680
            PP+  E L D     G+ ++ +C++ G P P + WYK  K ++   +  +    D    L
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             +      D G Y C A ++AG  +   K+ V  P +  N    +P       EG+ AQF
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVLASPF-----VEGEDAQF 6127

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRATTA 4798
               I     P I+W ++GAL+     FQ + E  +   VL+I    +ED G + C     
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187

Query: 4799 AGQVETSAKLVVKS 4812
             G    SA+L ++S
Sbjct: 6188 LGSARASAELRIQS 6201



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 57/208 (27%), Positives = 103/208 (49%), Gaps = 8/208 (3%)

Query: 4514 PSFTLTAQNVNVTSG-QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            P      +++ V  G +L +   KV G     +YW K+G+ +      ++ ++   +TL 
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLP-ATKDKPKPQTKAANAPPEIIEPLKD 4631
            I+    +DSG+Y     N+ G A   A  +V  P   ++KP         PP ++E    
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTP 5379

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWY-----KGDKLIKP-SKYFQMSRTADEYTLRISEA 4685
            K V +G +I FS K+ G+P+PTV W      +G   I P +  + ++ +A +++L + + 
Sbjct: 5380 KKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDV 5439

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
              + +G Y C+A N+AG+   +A L V+
Sbjct: 5440 GRQHQGTYTCIASNAAGQALCSASLHVS 5467



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/230 (29%), Positives = 107/230 (46%), Gaps = 9/230 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT-SIFRFGYIS 695
            P F+  L++    +G  + F+  +   G P   + W K+G+ +E    +  +  + G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT-IERTSQHPETLQYIQQLEDYS 754
            L + ++   D G Y C A ++ GV+ TKA L V   +T  +  +   E+  Y    + Y 
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA-QGYL 5242

Query: 755  KYQHQESIEEQTS--QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
              + QE  E  T   Q PQ +  L+DL      R A F  QL     P  R+ W+KDG+P
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKF--QLKVKGYPAPRLYWFKDGQP 5300

Query: 813  ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +TAS+ I         +L I+ +  ED+G Y     N +G A S+A + V
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 60/202 (29%), Positives = 92/202 (45%), Gaps = 5/202 (2%)

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
            Q + + AP  +  P K  +V+ G+    SC+IVG P P V W K  + +     F++++ 
Sbjct: 3    QPQFSGAPRFLTRP-KAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQD 61

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNLP-ALTPLRDIVV 4732
             D Y L I +    D G Y C A N+ G    A  L+V  +   A+  P  L     I V
Sbjct: 62   GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRV 121

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALI--PETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             EG  A F+ ++    +P + W ++G  +  P+ P  ++   G  + L I      D GT
Sbjct: 122  REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181

Query: 4791 FTCRATTAAGQVETSAKLVVKS 4812
            +  RA    G    +A LVV S
Sbjct: 182  YEVRAENPLGAASAAAALVVDS 203



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 92/364 (25%), Positives = 153/364 (42%), Gaps = 26/364 (7%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYV 1768
            APVF   +++  V +     F+   +  G P   V W ++G  +E  +      D  G  
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQ--LESQHESALQKIQQLED 1826
             L +  V P D G Y C A N +G + T + L V   ++         ES+     Q   
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
            SSR Q   +      Q P+ + +L         + A ++ +++ YP P  R+ W+ +G+ 
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYWFKDGQP 5300

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946
            L +    R ++      L+I++V  EDSG+Y     N +G A SS RL V+  +    + 
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD----EP 5356

Query: 1947 QHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND 2006
            + + A +  + L      +R      F  +K + G  I  +   EG PV     L    +
Sbjct: 5357 EEKPASDVHEQLVPPRMLER------FTPKKVKKGSSITFSVKVEGRPVPTVHWLR--EE 5408

Query: 2007 PTMRVEWYCNGRPVQQGHRF-KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
                V W     P   G+    +      V LD+     +  GTY C A+NA G+A+ ++
Sbjct: 5409 AERGVLWI---GPDTPGYTVASSAQQHSLVLLDV---GRQHQGTYTCIASNAAGQALCSA 5462

Query: 2066 SVKV 2069
            S+ V
Sbjct: 5463 SLHV 5466



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F +   D     G+  +  CRVTG P P ++W+ + + ++ D +H ++ +  G+ AL+
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            + ++T  DSG   C A + +G  +   ++ V      V P+FV +       EGE     
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVLASPFVEGEDAQFT 6128

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVA 569
                G P P+I W KDG  +    + +  ++   G   L I  A   D   Y+C   N  
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188

Query: 570  GSTATRARL 578
            GS    A L
Sbjct: 6189 GSARASAEL 6197



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 59/243 (24%), Positives = 106/243 (43%), Gaps = 27/243 (11%)

Query: 266  PKIAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P++ ++ R+ ++  G   A+FQ+++ G P PR+ WFK+GQ L  S    +       TL 
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            + +  + DSG Y     N  G   +S  L V  P E                 E +   +
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEP----------------EEKPASD 5363

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-----IRDDYNHK 439
            + E+ + P+ ++    + V +G    F  +V GRP P V W   + +     I  D    
Sbjct: 5364 VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423

Query: 440  ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-----IEKEQVVAPKFV 494
             + + +  H+L++ +V     G  TC+A N +G+      L+V     +E+++ V    +
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 5483

Query: 495  ERF 497
              F
Sbjct: 5484 STF 5486



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 90/406 (22%), Positives = 162/406 (39%), Gaps = 48/406 (11%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T  +Q     E   A F  E   E    ++W     P+ N    +I     +  L+++ +
Sbjct: 2561 TGPLQDAEATEEGWASFSCELSHEDEE-VEWSLNGMPLYNDSFHEISHKGRRHTLVLKSI 2619

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
               D+ +       R  + K S +  +E +       + P  F     +++      + L
Sbjct: 2620 QRADAGIV------RASSLKVSTSARLEVR-------VKPVVFLKALDDLSAEERGTLAL 2666

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              +V+  +   V W K+G ++ P  +   L   GT  L++ +  P+D+G Y C   +   
Sbjct: 2667 QCEVSDPEA-HVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEET 2725

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR                    +  +    I + LK   V EG++  F C +  +    
Sbjct: 2726 RAR-------------------VRVHDLHVGITKRLKTMEVLEGESCSFECVLSHESASD 2766

Query: 4654 -VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
               W  G K +  S  FQ +R   +Y L + EA P D G+   V ++  G +T  A L V
Sbjct: 2767 PAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGE---VVFSVRG-LTSKASLIV 2822

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
             +   A     + PL D  V  G+  + + +++    P + WL++   I ++  + ++ E
Sbjct: 2823 RERPAA----IIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCE 2877

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRA----TTAAGQVETSAKLVVKSKT 4814
            G  A+L+I     +D G +TC      +TA+  VE  A    +  T
Sbjct: 2878 GTMAMLVIRGASLKDAGEYTCEVEASKSTASLHVEEKANCFTEELT 2923



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 9/231 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYVA 2036
            P F   ++N EV +G+PV  +  +T    P   V W+ +G+ +++   +    D  G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096
            L I      D G Y C A N++G + T + ++VD  S  Y    D          + Y  
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243

Query: 2097 PKPIEEEQP----GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
             +  E  +     GQ P  +  L  L+       A F+ +V+    P L   WF +GQ +
Sbjct: 5244 SREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLY--WFKDGQPL 5301

Query: 2153 RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
             A    R T       L+I+    EDSG Y    +N +G A ++  L V G
Sbjct: 5302 TASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 99/393 (25%), Positives = 157/393 (39%), Gaps = 53/393 (13%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSILIIRQVFVEDSAV 4480
            V E   A F           + W+ +  P+  +   +I        +L +RQ+ ++DS  
Sbjct: 3016 VQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGT 3075

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
                A    G  + SA L V EK         P  F+    +  +T G+ + L  + T T
Sbjct: 3076 IYFEA----GDQRASAALRVTEK---------PSVFSRELTDATITEGEDLTLVCE-TST 3121

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
              I + W K+GK ++   R ++  E     LLI  A  QDSG+Y+C     AG A C + 
Sbjct: 3122 CDIPMCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC----EAGGA-CSSS 3176

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             V              +    P    E LKD  V EG A    C +     P V+W  G+
Sbjct: 3177 IV--------------RVHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGN 3221

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
             +++P   + + +      L +    P+D G Y C    S G  T +A L VT       
Sbjct: 3222 NVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTA------ 3271

Query: 4721 LPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778
            LPA  +  LR+    EG  A  + ++ SK  P ++W +    + +   + +  +G    L
Sbjct: 3272 LPAQFIGKLRNKEATEGATATLRCEL-SKTAP-VEWRKGSETLRDGDRYCLRQDGAMCEL 3329

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             I      D   ++C      G+  TSA L ++
Sbjct: 3330 QIRGLAMVDAAEYSC----VCGEERTSASLTIR 3358



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 106/440 (24%), Positives = 180/440 (40%), Gaps = 56/440 (12%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            I R++ + +  EI+  A+  E   +  VK   P    + ++     E  +   E +    
Sbjct: 2258 IYRRVLAEDAGEIQFVAENAESRAQLRVK-ELPVTLVRPLRDKIAMEKHRGVLECQVSRA 2316

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
                ++W++ +  ++  P +++ +      LII  V  ED   +   A    G  K SA 
Sbjct: 2317 SAQ-VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQ 2371

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVT--SGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              VEE+      G+         Q+V V   +      +T +   +P    WL  GK V 
Sbjct: 2372 FFVEEQSITIVRGL---------QDVTVMEPAPAWFECETSIPSVRPPK--WLL-GKTVL 2419

Query: 4556 PDIRNKILEEDGT-YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                N  LE++GT + L++       +G        + G++R  A  VVS          
Sbjct: 2420 QAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHF----TVGKSRSSARLVVS---------- 2465

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSR 4673
                 + P  +  PL+ K   E Q++  SC    +P P  VQWYK D  + PS+ F+MS 
Sbjct: 2466 -----DIPVVLTRPLEPKTGRELQSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSL 2518

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  LRI    P D G Y+C     AG    + ++ V    +A  +    PL+D    
Sbjct: 2519 EGQMAELRILRLMPADAGVYRC----QAGSAHSSTEVTV----EAREVTVTGPLQDAEAT 2570

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            E   A F  +++ +    ++W   G  +      ++ H+G    L++ +    D G    
Sbjct: 2571 EEGWASFSCELSHE-DEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG--IV 2627

Query: 4794 RATTAAGQVETSAKLVVKSK 4813
            RA++   +V TSA+L V+ K
Sbjct: 2628 RASSL--KVSTSARLEVRVK 2645



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 69/232 (29%), Positives = 99/232 (42%), Gaps = 13/232 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI-EASNRLTTMHDFGY 1767
            QAP F +    IRV E   A F  R+   G P+  V W ++G  + E       + + G 
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRV--GGSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165

Query: 1768 V-ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLED 1826
              AL ++   P D GTY  RA N LG A  ++ L V S A+        S    +  L+ 
Sbjct: 166  ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ- 224

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                +RRE +      A    T     T ++EG+ A   C +   P P     W  +G++
Sbjct: 225  ----RRREAMRAEGAPASPPSTGTRTCT-VTEGKHARLSCYVTGEPKP--ETVWKKDGQL 277

Query: 1887 LQSGHRYRTSNDF-GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            +  G R+    D      L IL     D G YTC A N +GQ  SS+ + V+
Sbjct: 278  VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 92/386 (23%), Positives = 153/386 (39%), Gaps = 38/386 (9%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-TETNNFGFV 1635
            AP+  T L+N E+++G    F+   +        V W+ + K L+    +    +  G  
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFD--CVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY----LESQHEGALPRLNQL 1691
             L I + +P D G Y C A N++G + T     V    + Y      ++          L
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAE-NQAAHFEARLIPVGDPKLRVEWLRNG 1750
                +    S  DE   Q P     ++D++VA   + A F+ ++   G P  R+ W ++G
Sbjct: 5243 SSREQEGTESTTDE--GQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKDG 5298

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             P+ AS  +          L +  V  EDSG Y     N +G A +S+ L V+       
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD---- 5354

Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870
            E + + A    +QL                   PR + +   P K+ +G S  +  ++E 
Sbjct: 5355 EPEEKPASDVHEQL-----------------VPPRMLERFT-PKKVKKGSSITFSVKVEG 5396

Query: 1871 YPDPNMR-VEWYFNGKVLQSG---HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             P P +  +       VL  G     Y  ++     +L +L V  +  G YTC A N  G
Sbjct: 5397 RPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG 5456

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESAL 1952
            QA+ S  L+V     +    + + AL
Sbjct: 5457 QALCSASLHVSGLPKVEEQEKVKEAL 5482



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 84/325 (25%), Positives = 133/325 (40%), Gaps = 22/325 (6%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F T  K  V +S G+ A     ++  G+ +  + W  + + + A  R R      +  
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQIV--GNPTPQVSWEKDQQPVTAGARFRLAQDGDLYR 66

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKG---QKPRFTTHIQNIEGLKDG 3164
            L IL     DSG Y CRA N  G+A  +V L+ VD       Q P F     +I  +++G
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQ-VDAEAACAEQAPHFLLRPTSIR-VREG 124

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRH--STRIKTVSDFGFV-VLDIAYTQNHDSGE 3221
              A F C V     P   + W  +G+ +      R++ V + G    L I   +  D G 
Sbjct: 125  SEATFRCRV--GGSPRPAVSWSKDGRRLGEPDGPRVR-VEELGEASALRIRAARPRDGGT 181

Query: 3222 YVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            Y  RA N  G     A +                + A +  L+  + A  +    P A P
Sbjct: 182  YEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA-MRAEGAP-ASP 239

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIV 3340
            P   T+   VT   EG+ A     +    +P  +  W  +G+ +  G R+  + D     
Sbjct: 240  PSTGTRTCTVT---EGKHARLSCYV--TGEPKPETVWKKDGQLVTEGRRHVVYEDAQENF 294

Query: 3341 ILDILYCYEENSGEYECVATNKLGR 3365
            +L IL+C + + G Y C A+N +G+
Sbjct: 295  VLKILFCKQSDRGLYTCTASNLVGQ 319



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 63/233 (27%), Positives = 101/233 (43%), Gaps = 7/233 (3%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S + PVF+  L N   V +G  +  +C +   G P   V WF +G+ +     +    D 
Sbjct: 5122 SDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQL 1290
             G   L I     AD G Y   A N +G + T A +RV +  +D  T     ++      
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238

Query: 1291 LEDAARRTKQVREDITVM-QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN 1349
                + R ++  E  T   Q PQ    L +++   GT +  + +L+  G    R+ WF +
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFKD 5297

Query: 1350 GKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            G+P+      R   +     L+++SV  EDSG Y    +N +G A +S  L V
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 34/92 (36%), Positives = 54/92 (58%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F+   Q+++V +G    FDC VTG+P P V WF + + + +D ++ I  ++ G H L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            +IT V  +D GV  C+A N  G ++ +  L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 65/220 (29%), Positives = 94/220 (42%), Gaps = 15/220 (6%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT--GSRVHTLNDFGFIALDIDYIY 3761
            +I V EG    F CRV   G P   + W  +GR      G RV         AL I    
Sbjct: 118  SIRVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAAR 175

Query: 3762 ARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPK 3821
             RD G Y  RA N  G+A+  A +   +  D    +  P   +   +  L+R R  +A +
Sbjct: 176  PRDGGTYEVRAENPLGAASAAAALVVDS--DAADTASRPGTSTAALLAHLQRRR--EAMR 231

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
             E   ++PP   T  ++ TV E +  R  C V    +PK    W ++G+L+  G R+   
Sbjct: 232  AEGAPASPPS--TGTRTCTVTEGKHARLSCYVTG--EPKPETVWKKDGQLVTEGRRHVVY 287

Query: 3882 YDM--GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             D    FV L IL+    D G Y C A N  G+ ++   +
Sbjct: 288  EDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 57/200 (28%), Positives = 88/200 (44%), Gaps = 14/200 (7%)

Query: 4428 ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAEN 4487
            A+F+++  G P P + W+++  P+  S   ++        L I  V  EDS  +AA   N
Sbjct: 5278 AKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISN 5337

Query: 4488 RGGTAKCSANLVV------EEKRRQG-RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
              G A  SA L+V      EEK        +VPP          V  G  +    KV G 
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR 5397

Query: 4541 KPIDVYWLKNGKK-----VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
                V+WL+   +     + PD     +      ++L++L+   Q  G Y C+A N+AG+
Sbjct: 5398 PVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457

Query: 4595 ARCDAECVVS-LPATKDKPK 4613
            A C A   VS LP  +++ K
Sbjct: 5458 ALCSASLHVSGLPKVEEQEK 5477



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 79/288 (27%), Positives = 115/288 (39%), Gaps = 19/288 (6%)

Query: 1835 DVEVA-VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL--QSGH 1891
            D E A   QAP F+ +     ++ EG  A + CR+   P P   V W  +G+ L    G 
Sbjct: 100  DAEAACAEQAPHFLLRPTS-IRVREGSEATFRCRVGGSPRP--AVSWSKDGRRLGEPDGP 156

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
            R R       +AL I      D G Y  +A N LG A ++  L V S  +        S 
Sbjct: 157  RVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTST 216

Query: 1952 LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
               + +L+   R + A++ +      P  G   +   VTEG    L   +T   +P    
Sbjct: 217  AALLAHLQ---RRREAMRAEGAPASPPSTGT--RTCTVTEGKHARLSCYVT--GEPKPET 269

Query: 2012 EWYCNGRPVQQGHRFKTTYDFGY-VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             W  +G+ V +G R     D      L IL+    D G Y C A+N VG+  T SSV V 
Sbjct: 270  VWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ--TYSSVLVV 327

Query: 2071 AKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSL 2118
             +         ++RL+ ++  EK       E  QP     +    T L
Sbjct: 328  VREPA---VPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRL 372



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 32/108 (29%), Positives = 60/108 (55%), Gaps = 1/108 (0%)

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
            P    +P P    ++A P  +  L+++ V +G  + F C + G+P+P+V+W+K  KL++ 
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEE 5168

Query: 4666 SKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
              ++ ++      + L I+   P D G Y+C+A NS G  +  A+L+V
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 7/239 (2%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SL 2833
            VF++ L N   ++G  + F+C V  +  P   + WF + K L     Y    D      L
Sbjct: 5127 VFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             IT     D G+Y C A NS G ++T   LR       Y         +   + +    +
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
            R  +G   +  + + P+   ++    + Q+  G  L  + Q++ K  P  ++ W+ +G+ 
Sbjct: 5245 REQEGTESTTDEGQLPQ---VVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFKDGQP 5300

Query: 2954 LEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
            L   +  ++T      TL+++ V   DSG Y     N  G A++S+ +     D   E+
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEK 5359



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 95/421 (22%), Positives = 163/421 (38%), Gaps = 45/421 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +F KK++P  V E      EVE    P P ++W R    +    + +IH    +  L+
Sbjct: 1987 PVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  V   D   F     +     K  A L VE ++ +   G+   +     Q       Q
Sbjct: 2046 LHNVGFADRGFFGCETPDD----KTQAKLTVEMRQVRLVRGL--QAVEAREQGTATMEVQ 2099

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
            L   D        +D  W ++G + Q      +      +TL +    P+DSG     A 
Sbjct: 2100 LSHAD--------VDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAE 2151

Query: 4590 NSAGEARCDA-ECVVSLP------ATKDKPKPQTKAANAPPEI-IEPLKDKI-VAEGQAI 4640
                 AR    E  VS         T +K K   +   + P + +  LKD + +  G+ +
Sbjct: 2152 GVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTM 2211

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD------EYTLRISEAFPEDEGDYK 4694
              + +   + L   +    D+ +          +A        YTL       ED G+ +
Sbjct: 2212 AIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQ 2271

Query: 4695 CVAYNSAGRVTVAAK-LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
             VA N+  R  +  K L VT          + PLRD +  E      + Q+ S+    ++
Sbjct: 2272 FVAENAESRAQLRVKELPVT---------LVRPLRDKIAMEKHRGVLECQV-SRASAQVR 2321

Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            W +    +   P ++++ +G    L+I + + ED  T+TC     AG V+TSA+  V+ +
Sbjct: 2322 WFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTC----DAGDVKTSAQFFVEEQ 2377

Query: 4814 T 4814
            +
Sbjct: 2378 S 2378



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 84/370 (22%), Positives = 146/370 (39%), Gaps = 47/370 (12%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W + +  ++    + +    T+  L I  + V D+  ++ V     G  + SA L V 
Sbjct: 3831 VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVR 3886

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
              +         P F    Q++    G    L  +++      V W K G ++Q + R +
Sbjct: 3887 APQ---------PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKGGLQLQANGRRE 3936

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
               +  T  L++ +   +D+G+Y C   + A  A        +L  T            A
Sbjct: 3937 PRLQGCTAELVLQDLQREDTGEYTCTCGSQATSA--------TLTVTA-----------A 3977

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   +  L+ + V EG      C++  +   +V+W KG   + P   +QM +      L 
Sbjct: 3978 PVRFLRELQHQEVDEGGTAHLCCEL-SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELL 4036

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            +     ED GDY C      G     A L V  P         T L+ +    G  A+  
Sbjct: 4037 VRGVEQEDAGDYTC----DTGHTQSMASLSVRVPRPKFK----TRLQSLEQETGDIARLC 4088

Query: 4742 TQIT-SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             Q++ ++    +QWL+EG  +   P ++M  +G    LLI     +DTG + C      G
Sbjct: 4089 CQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC----VTG 4144

Query: 4801 QVETSAKLVV 4810
              +T+A L V
Sbjct: 4145 GQKTAASLRV 4154



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 81/369 (21%), Positives = 144/369 (39%), Gaps = 49/369 (13%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W++ +  +++     +     +  L IR +  ED+  +  +     G  + SA L V 
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVR 3710

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
                      +P  F    +N   T G    L  +++   P++  W K  + ++   R+ 
Sbjct: 3711 A---------MPSKFIEGLRNEEATEGDTATLWCELSKAAPVE--WRKGHETLRDGDRHS 3759

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            + ++     L I      D+G+Y CV     G+ R  A   V                  
Sbjct: 3760 LRQDGSRCELQIRGLAVVDAGEYSCVC----GQERTSATLTVRA---------------L 3800

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   IE +K++   EG      C++  K  P V+W KG + ++    + + +      L+
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQ 3858

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I      D G+Y CV     G+   +A L V  P          PL+ +   EG  A  +
Sbjct: 3859 IHGLSVADTGEYSCV----CGQERTSATLTVRAPQPVFR----EPLQSLQAEEGSTATLQ 3910

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             ++ S+   T+ W + G  +      +   +G  A L++ +   EDTG +TC      G 
Sbjct: 3911 CEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC----TCGS 3965

Query: 4802 VETSAKLVV 4810
              TSA L V
Sbjct: 3966 QATSATLTV 3974



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 99/448 (22%), Positives = 173/448 (38%), Gaps = 45/448 (10%)

Query: 4349 DPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPS 4408
            DP+  TV GK V  + + Q  ++      + R+   ++  E+    +         V+  
Sbjct: 2766 DPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVR-E 2824

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +P    K ++   V   E      E      P + W ++   I+ S  + +    T ++L
Sbjct: 2825 RPAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAML 2883

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +IR   ++D+  +    E     +K +A+L VEEK            FT    N+ V   
Sbjct: 2884 VIRGASLKDAGEYTCEVE----ASKSTASLHVEEKAN---------CFTEELTNLQVEEK 2930

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                   K T      V W K   +++   +++  +E  T  L I      DS  Y C  
Sbjct: 2931 GTAVFTCK-TEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTC-- 2987

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
                G+A+  A+ +V           Q +  +    IIE L+D  V EG +  F C+I  
Sbjct: 2988 --DIGQAQSRAQLLV-----------QGRRVH----IIEDLEDVDVQEGSSATFRCRISP 3030

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
                 V W+     +  ++  ++      Y  L + +   +D G      Y  AG    +
Sbjct: 3031 ANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG----TIYFEAGDQRAS 3086

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            A L+VT+     +      L D  + EG+      + TS     + W ++G  +  +   
Sbjct: 3087 AALRVTEKPSVFS----RELTDATITEGEDLTLVCE-TSTCDIPMCWTKDGKTLRGSARC 3141

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            Q+ HEG+ A LLI     +D+G + C A
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEA 3169



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 47/198 (23%), Positives = 82/198 (41%), Gaps = 9/198 (4%)

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
            + + R ++  +      ++  +D DV EG    F CR++   Y  V WF++   +  +  
Sbjct: 2991 QAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANEL 3050

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
            ++I     G H L +  + L DSG +      ++G+      L V EK  V    F    
Sbjct: 3051 NEIDAQPGGYHVLTLRQLALKDSGTIYF----EAGDQRASAALRVTEKPSV----FSREL 3102

Query: 498  STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            +   + EGE + L         P + W KDG  +  +   ++  +G  + L I  A   D
Sbjct: 3103 TDATITEGEDLTLVCETSTCDIP-MCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQD 3161

Query: 558  AAWYQCTAQNVAGSTATR 575
            +  Y+C A     S+  R
Sbjct: 3162 SGRYKCEAGGACSSSIVR 3179



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 118/538 (21%), Positives = 212/538 (39%), Gaps = 53/538 (9%)

Query: 4280 KLQELENEQVIKESRLRESTHQYAIP-GDKVTSNTVAKSMAQ-RYEDNLDQTEEVTEQRV 4337
            +LQ    E V+++ + RE T +Y    G + TS T+  + A  R+   L Q +EV E   
Sbjct: 3938 RLQGCTAELVLQDLQ-REDTGEYTCTCGSQATSATLTVTAAPVRFLREL-QHQEVDEGGT 3995

Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQ 4397
                 +  R     E      ++    + Q  ++    + + R +   +  +        
Sbjct: 3996 AHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHT 4055

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEF-DGEPLPLIKWYRENFPIKNSPD 4456
            + +    V+  +P  F  ++Q       + AR   +  D E   +++W +E   +   P 
Sbjct: 4056 QSMASLSVRVPRPK-FKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPK 4114

Query: 4457 FQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
            +++ +      L+I Q+  +D+  +A V     G  K +A+L V E       G+V    
Sbjct: 4115 YEMRSQGATRELLIHQLEAKDTGEYACVT----GGQKTAASLRVTEPEVTIVRGLV---- 4166

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLILE 4575
                 +  VT+ + V    +V+      V W   G  +Q +   ++   DG  +TL +  
Sbjct: 4167 -----DAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKG 4221

Query: 4576 AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA 4635
              P+D+G       N A  A    +  V  P                  I+EPL+D  ++
Sbjct: 4222 VTPEDAGTVSFHLGNHASSA----QLTVRAPEVT---------------ILEPLQDVQLS 4262

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            EGQ   F C++        +W  G   ++ ++   +  T ++ TL +         D   
Sbjct: 4263 EGQDASFQCRLSRASGQEARWALGGVPLQANEMNDI--TVEQGTLHLLTLHKVTLEDAGT 4320

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            V+++  G  +  A+LKVT    A N   +  L ++   EG  A F+ Q++        WL
Sbjct: 4321 VSFH-VGTCSSEAQLKVT----AKN-TVVRGLENVEALEGGEALFECQLSQPEVAAHTWL 4374

Query: 4756 --REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               E     E  +      G   +LL+ N   +D    +CR T  AG + TSA L V+
Sbjct: 4375 LDDEPVRTSENAEVVFFENGLRHLLLLKNLRPQD----SCRVTFLAGDMVTSAFLTVR 4428



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 103/439 (23%), Positives = 178/439 (40%), Gaps = 54/439 (12%)

Query: 2043 YAEDTGTYMCKATNAVGEA--VTTSSVKVDAKSGLYLDT-LDEQRLKKIQELEKYERPKP 2099
            Y ED   ++C    A+ EA    T   ++ A  G+ ++  L EQ  ++++     E P P
Sbjct: 5051 YREDEH-FICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPAP 5109

Query: 2100 IEEEQP-------GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
            +   +P          PVFLT L + E +++G    F+C V     P  ++ WF +G+ +
Sbjct: 5110 VVPPEPLPSLLTSDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLL 5166

Query: 2153 RAGHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
                 Y    D  G   L I      D G Y C A N +G +     L+V    +   DT
Sbjct: 5167 EEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV-DLTSTDYDT 5225

Query: 2212 QHPNGLEKIRQLEAQGHSTRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQV 2266
               +  E      AQG+ +  E E  + +      P+ V ELR        + A F+ +V
Sbjct: 5226 A-ADATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV 5284

Query: 2267 EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHC 2326
            +    P  R+ ++ +G+ L ++A   +T      +L+I     ED+G+Y+    NA+G  
Sbjct: 5285 KGYPAP--RLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342

Query: 2327 TSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNID 2386
             S+  + V              G ++  E  +++  ++   P  + R  P          
Sbjct: 5343 YSSARLLV-------------RGPDEPEEKPASDVHEQLVPPRMLERFTP---------K 5380

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK------LIEDSSRITKTHDFGYVSMTISH 2440
             +++G +  F  ++   G P   V W R E       +  D+   T        S+ +  
Sbjct: 5381 KVKKGSSITFSVKV--EGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLD 5438

Query: 2441 VRDEDEGVYMCRASNLLGE 2459
            V  + +G Y C ASN  G+
Sbjct: 5439 VGRQHQGTYTCIASNAAGQ 5457



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 91/366 (24%), Positives = 138/366 (37%), Gaps = 46/366 (12%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PRF+TRPK+   V  G+     C++  V +   +V W K+ QPVT G RFR         
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFR--------- 57

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
                  +A+D  +Y    ++L   D  S +  CR+   I  +     GL+          
Sbjct: 58   ------LAQDGDLYRLTILDLALGD--SGQYVCRARNAIGEAFA-AVGLQ---------- 98

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPL--K 1621
                D       QAP       ++ ++EG  A F  R+         V W  + + L   
Sbjct: 99   ---VDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRV--GGSPRPAVSWSKDGRRLGEP 153

Query: 1622 SGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQH 1681
             G R          AL I +  P D GTY  RA N LG A  +   +V S  +       
Sbjct: 154  DGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPG 213

Query: 1682 EGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPK 1741
                  L  L+     +R + + E    +P  T   +   V E + A     +   G+PK
Sbjct: 214  TSTAALLAHLQ----RRREAMRAEGAPASPPST-GTRTCTVTEGKHARLSCYV--TGEPK 266

Query: 1742 LRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
                W ++G  +    R     D      L + +    D G YTC A N +G+  +S  +
Sbjct: 267  PETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326

Query: 1801 FVQSKA 1806
             V+  A
Sbjct: 327  VVREPA 332



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 91/367 (24%), Positives = 140/367 (38%), Gaps = 27/367 (7%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR-ITSIFNFGYV 828
            P F+  LQ+  E+Q+G    F+  +T    P   V W+KDG+ +      + +    G  
Sbjct: 5126 PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXX 888
             L I  +   D G Y   A N +G + + A +RV   ST   D                 
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTST---DYDTAADATESSSYFSAQ 5239

Query: 889  XXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKD 948
                           +  Q P+    ++D         A F+ +++  G    R+ W KD
Sbjct: 5240 GYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFKD 5297

Query: 949  GRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
            G+P+ AS+ I          L I SVT  D+G Y     NA+G A +SA L +V   D  
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL-LVRGPD-- 5354

Query: 1009 AESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVE 1068
             E +     +  + L       + T ++VK      F   ++G        + H+  R E
Sbjct: 5355 -EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR----PVPTVHW-LREE 5408

Query: 1069 PQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQ 1128
             +      V W   G          +      V LD+     +  G YT +A NAAG+A 
Sbjct: 5409 AERG----VLWI--GPDTPGYTVASSAQQHSLVLLDVG---RQHQGTYTCIASNAAGQAL 5459

Query: 1129 LSASMTV 1135
             SAS+ V
Sbjct: 5460 CSASLHV 5466



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 78/337 (23%), Positives = 123/337 (36%), Gaps = 56/337 (16%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+   +P+   +  G DA    Q+ GNP P+V+W K+ Q +    +  +    +   L +
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTI 69

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
            +    DSG Y   A N  G    +  L V++  E+   +Q   ++              
Sbjct: 70  LDLALGDSGQYVCRARNAIGEAFAAVGLQVDA--EAACAEQAPHFL-------------- 113

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE- 444
               L P  ++V       EG    F CRV G P P V+W  + R++ +    ++ V E 
Sbjct: 114 ----LRPTSIRV------REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 445 ---------------SGNHALMITNVTLSDSGVVTCVARNKSGETA-------------F 476
                           G + +   N   + S     V  + + +TA              
Sbjct: 164 GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHL 223

Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536
           Q R   +  E   A        T  V EG+   L+    G P P   W+KDG  +     
Sbjct: 224 QRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR 283

Query: 537 LRIHTDGGAS-TLDIPRAKASDAAWYQCTAQNVAGST 572
             ++ D   +  L I   K SD   Y CTA N+ G T
Sbjct: 284 HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 68/236 (28%), Positives = 104/236 (44%), Gaps = 18/236 (7%)

Query: 1041 QKPRFLGPLKGTN-KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN--RIQTYHD 1097
            Q P FL  L+ T+ ++ EG  A F  RV         V W  +G+++   +  R++    
Sbjct: 108  QAPHFL--LRPTSIRVREGSEATFRCRVGGSP--RPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
                AL I + R  D G Y V A N  G A  +A++ V++ ++   S           H+
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHL 223

Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
            +  +  E M + E    S P      +    V+EGK+  L C +   G+P     W  +G
Sbjct: 224  QRRR--EAM-RAEGAPASPP---STGTRTCTVTEGKHARLSCYVT--GEPKPETVWKKDG 275

Query: 1218 RSVTVGSRFKTYYDF--GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            + VT G R   Y D    FV L I+    +D G YT  A N +G  ++S +V V E
Sbjct: 276  QLVTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 86/408 (21%), Positives = 164/408 (40%), Gaps = 42/408 (10%)

Query: 4390 IEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449
            IE   + + R   G +  +KPP    +    R+  HE+A+   E   +    + W ++  
Sbjct: 689  IESSIRMEVRAAPG-LTANKPPAAAAREVLARL--HEEAQLLAELSDQAAA-VTWLKDGR 744

Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
             +   P +++   + + +L++R V  +D+ ++  V+  RGG  + +  L V     QG  
Sbjct: 745  TLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVS--RGG--RIAYQLSV-----QGLA 795

Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT- 4568
              +     +    V+  +G   + + + T    + V+W K+G ++       + E+ GT 
Sbjct: 796  RFLHKD--MAGSCVDAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTR 852

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            + L+      QD G Y C      GE   D    VS P          K   A  ++   
Sbjct: 853  HRLVAATVTRQDEGTYSC----RVGEDSVDFRLRVSEP----------KVVFAKEQLA-- 896

Query: 4629 LKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
             + K+ AE G +   SC+ V +    V WYK  K +  S    M  T     L + +A  
Sbjct: 897  -RRKLQAEAGASATLSCE-VAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQ 954

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
             D G+Y C     AG   ++  L V +P        +    ++    G  A    ++ ++
Sbjct: 955  ADAGEYSC----EAGGQRLSFHLDVKEPKVVFAKDQVAH-SEVQAEAGANATLSCEV-AQ 1008

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
             +  + W ++G  +  +    +  +G    L++    + D G ++C A
Sbjct: 1009 AQAEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 115/497 (23%), Positives = 193/497 (38%), Gaps = 63/497 (12%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+++   C +  +  P   + W  + K +    +Y    + +   L I     +D+G YT
Sbjct: 2841 GEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897

Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTE 2907
            C+   SK +A    SL      N + +         L+  E+       K   P+   T 
Sbjct: 2898 CEVEASKSTA----SLHVEEKANCFTEEL-----TNLQVEEKGTAVFTCKTEHPAATVT- 2947

Query: 2908 YPKPEWIIPIAAEHQ-LVEGQVLHLEGQVEPKNDPDLKI----EWYFNGKVLEQGSRFKL 2962
            + K    +  + +HQ   EG  L L      K D D       +     ++L QG R  +
Sbjct: 2948 WRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHI 3007

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA---FTSSTVYCTSKDNLIERTQHPKGT 3019
              D     L+ VDV E  S  + C+      E    F   T    ++ N I+    P G 
Sbjct: 3008 IED-----LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDA--QPGGY 3060

Query: 3020 EGLEKIQ-NLEDS--LRKEPGQQPDDDTGRPPEFTTVF-KDIVD--ISEGQIAHYEASLI 3073
              L   Q  L+DS  +  E G Q      R  E  +VF +++ D  I+EG+    + +L+
Sbjct: 3061 HVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE----DLTLV 3116

Query: 3074 -PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
              T    + + W  +GKT+  S R +  +      L I G    DSG Y C A      +
Sbjct: 3117 CETSTCDIPMCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSS 3176

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
             + V    V        RF   ++++E L +G +A   C +  V  P   ++W +    +
Sbjct: 3177 IVRVHARPV--------RFQEALKDLEVL-EGGAATLRCVLSSVAAP---VKWCYGNNVL 3224

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESL 3252
            R   +     +   + L +   +  DSG Y C     +G+  T AT+         + +L
Sbjct: 3225 RPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLT--------VTAL 3272

Query: 3253 QPDSLAKIRELESLQGA 3269
                + K+R  E+ +GA
Sbjct: 3273 PAQFIGKLRNKEATEGA 3289



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 101/447 (22%), Positives = 172/447 (38%), Gaps = 48/447 (10%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P F T   +  + +     F+C  +        V WF +GK L          D  G   
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 5183

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V   D G+Y C A N  G ++   +L+V     +       +   + + S    +
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVD----LTSTDYDTAADATESSSYFSAQ 5239

Query: 3677 ETLHKREEITIED--EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
              L  RE+   E   ++   P+   E++D    P      F  +V+  G P  R+ WF +
Sbjct: 5240 GYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFKD 5297

Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            G+P    + +   +      L+I  +   D+G+Y    +N  G+A ++A++         
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL--------- 5348

Query: 3795 LESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVE 3854
                L +G       E E    SD    E +V  PP+ + +     V++   + F  +VE
Sbjct: 5349 ----LVRGPD-----EPEEKPASDV--HEQLV--PPRMLERFTPKKVKKGSSITFSVKVE 5395

Query: 3855 PKEDPKLRIEWYR----NGKLL--PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
             +  P   + W R     G L   P    Y         SL +L V  +  G Y C A N
Sbjct: 5396 GRPVP--TVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASN 5453

Query: 3909 DFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTED--DLYD 3966
              G+    A++    LP +  Q +V    K +   T ++ T +  +++ + T    DL  
Sbjct: 5454 AAGQALCSASLHVSGLPKVEEQEKV----KEALISTFLQGTTQAISAQGFQTASFADL-G 5508

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKF 3993
              +K+ P    +     SL E+ T +F
Sbjct: 5509 GQRKEEPLAAKEALGHLSLAEVGTEEF 5535



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 17/241 (7%)

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGASTL 548
            AP F+       V++G PV  +    G P P + W KDG  +  +    I+ D  G   L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXX 608
             I     +D   Y+C A+N  G ++T+A L                              
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDT---------AADATESSSY 5235

Query: 609  XXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKI-HFETRIEPVGDPT 667
                 YL   E+        E       PQ +  L+ +    G ++  F+ +++  G P 
Sbjct: 5236 FSAQGYLSSREQEGTESTTDEGQL----PQVVEELRDLQVAPGTRLAKFQLKVK--GYPA 5289

Query: 668  MKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLH 727
             ++ W K+GQ + AS+      +    +L+++S+  +DSG+Y     +A G A + A L 
Sbjct: 5290 PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLL 5349

Query: 728  V 728
            V
Sbjct: 5350 V 5350



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 90/382 (23%), Positives = 154/382 (40%), Gaps = 32/382 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL-KVEWFKNGQPVTIGHRFRPIHDF-GY 1501
            P F+T  ++ E V +G  V F+C    VT   +  V WFK+G+ +     +    D  G 
Sbjct: 5126 PVFLTELQNQE-VQDGYPVSFDCV---VTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST-TDI---VRSTQNEAGLEQIQV 1557
              L I  ++  D G+Y C A N +G       L    T TD      +T++ +       
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 1558 LEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR-AHFERRLIPVSDATLKVEWYHN 1616
            L  R +       DE   Q P     L+++++  G R A F+ ++        ++ W+ +
Sbjct: 5242 LSSREQEGTESTTDE--GQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKD 5297

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY 1676
             +PL + +    T+      L+I+S   EDSG Y     NA+G A +S   +V       
Sbjct: 5298 GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD--- 5354

Query: 1677 LESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
             E + + A     QL      +R + +      +  F++ ++   V        EA    
Sbjct: 5355 -EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---- 5409

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
                +  V W+    P          H     +L +  V  +  GTYTC A N  G+A+ 
Sbjct: 5410 ----ERGVLWIGPDTPGYTVASSAQQH-----SLVLLDVGRQHQGTYTCIASNAAGQALC 5460

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
            S++L V     ++ + + + AL
Sbjct: 5461 SASLHVSGLPKVEEQEKVKEAL 5482



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 89/404 (22%), Positives = 157/404 (38%), Gaps = 50/404 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            KP +F++++    + E E      E     +P+  W ++   ++ S   Q+     ++ L
Sbjct: 3094 KPSVFSRELTDATITEGEDLTLVCETSTCDIPMC-WTKDGKTLRGSARCQLSHEGHRAQL 3152

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +I    ++DS  +   A   GG   CS+++V    R        P  F    +++ V  G
Sbjct: 3153 LITGATLQDSGRYKCEA---GGA--CSSSIVRVHAR--------PVRFQEALKDLEVLEG 3199

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                L   V  +    V W      ++P  +  + +E     L++    PQDSG+Y C  
Sbjct: 3200 GAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC-- 3256

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
              S G+    A   V+                 P + I  L++K   EG      C++  
Sbjct: 3257 --SFGDQTTSATLTVTA---------------LPAQFIGKLRNKEATEGATATLRCEL-S 3298

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            K  P V+W KG + ++    + + +      L+I      D  +Y CV     G    +A
Sbjct: 3299 KTAP-VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCV----CGEERTSA 3353

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L + +P  A  +  L     I   EG  A  + ++ SK  P ++W +    + +     
Sbjct: 3354 SLTI-RPMPAHFIGRLRHQESI---EGATATLRCEL-SKAAP-VEWRKGRESLRDGDRHS 3407

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            +  +G    L I      D G ++C      G+  TSA L VK+
Sbjct: 3408 LRQDGAVCELQICGLAVADAGEYSC----VCGEERTSATLTVKA 3447



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 38/130 (29%), Positives = 68/130 (52%), Gaps = 6/130 (4%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V   PRF+ ++   +   EG+ A + C IE  P P +R  WY +G +L +G++++T 
Sbjct: 6101 KILVQVPPRFVNKVLA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTL 6157

Query: 1897 ND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH-ESALE 1953
            ++   G   L I     ED G Y C+ +N LG A +S  L +QS     ++  H E  + 
Sbjct: 6158 SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVA 6217

Query: 1954 KIQYLEDDSR 1963
             ++  E +++
Sbjct: 6218 AVEVTEQETK 6227



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 63/221 (28%), Positives = 88/221 (39%), Gaps = 13/221 (5%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KTGHRFRPAYEFD 1366
            QAP F     +I   EG+     CR+   G     V W  +G+ +    G R R     +
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426
              AL + +  P D G Y  +A N LG A  S A  ++   D    +  P G      L  
Sbjct: 166  ASALRIRAARPRDGGTYEVRAENPLGAA--SAAAALVVDSDAADTASRP-GTSTAALLAH 222

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
              R ++    + +    P   TR  +   V EG+H    C +    +   +  W K+GQ 
Sbjct: 223  LQRRREAMRAEGAPASPPSTGTRTCT---VTEGKHARLSCYV--TGEPKPETVWKKDGQL 277

Query: 1487 VTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            VT G R     D      L I+     D G+YTC A NLVG
Sbjct: 278  VTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 78/361 (21%), Positives = 143/361 (39%), Gaps = 36/361 (9%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   +  S   ++        L+++Q    D+  ++  A    G+ + S +L V 
Sbjct: 1473 VMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQADAGEYSCEA----GSQRLSFHLHVA 1528

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E +       V       ++ V   +G    L  +V   +  +V W K+GKK+    + +
Sbjct: 1529 EPKA------VFAKEQPASREVQAEAGTSATLSCEVAQAQT-EVTWYKDGKKLSSSSKVR 1581

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +     T  L++ EA   D+G+Y C     AG+ R      V+ P          K   A
Sbjct: 1582 MEAVGCTRRLVVQEAGQADAGEYSC----KAGDQRLSFHLHVAEP----------KVVFA 1627

Query: 4622 PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
              +   P   ++ AE G +   SC+ V +    V WYK  K +  S   ++        L
Sbjct: 1628 KEQ---PAHREVQAEAGASATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRL 1683

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             + +A   D G+Y C A     R++    +   +P  ++      PL   VV E +    
Sbjct: 1684 VVQQAGQADAGEYSCEA--GGQRLSFRLHVAELEPQISERPCRREPL---VVKEHEDIIL 1738

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
               + +    T+ WL++G  I  +   +   +G+   L +      D+  ++CR   A G
Sbjct: 1739 TATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCR-VGAEG 1797

Query: 4801 Q 4801
            Q
Sbjct: 1798 Q 1798



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 64/236 (27%), Positives = 102/236 (43%), Gaps = 12/236 (5%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTFFN 963
            S   P F T +++Q  +++G    F+  +   G     V W KDG+ +E     +     
Sbjct: 5122 SDAAPVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI---VTKKDIIAESQHPGGLEKI 1020
             G   L I +V   D G Y C A N++G ++T A L +    T  D  A++         
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238

Query: 1021 Q-YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEW 1079
            Q YL  +SR  + TE      Q P+ +  L+        + A F+ +V+        + W
Sbjct: 5239 QGYL--SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYP--APRLYW 5294

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            + +G+ +T++  I+         L+I SV  EDSG Y     NA G A  SA + V
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 62/213 (29%), Positives = 86/213 (40%), Gaps = 14/213 (6%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV--GSRFKTYYDFGFVALDIIHATSAD 1246
            V EG      CR+   G P   V W  +GR +    G R +        AL I  A   D
Sbjct: 121  VREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT 1306
             G Y VRA N LG+A  SA   ++  SD   DT +        LL    RR + +R +  
Sbjct: 179  GGTYEVRAENPLGAA--SAAAALVVDSD-AADTASRPGTSTAALLAHLQRRREAMRAEGA 235

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF- 1365
                P  S         EG +  L C +   G+      W  +G+ +  G R    YE  
Sbjct: 236  PASPP--STGTRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQLVTEGRR-HVVYEDA 290

Query: 1366 -DYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             +   L +L     D G+YTC A+N +G+  +S
Sbjct: 291  QENFVLKILFCKQSDRGLYTCTASNLVGQTYSS 323



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 73/324 (22%), Positives = 126/324 (38%), Gaps = 29/324 (8%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P   + W+ +GK+LE+   + +  D  G   L +  V   D G+Y C A N  G + T +
Sbjct: 5153 PMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKA 5212

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD 3059
             +         +       +      Q    S R++ G +   D G+ P+     +D+  
Sbjct: 5213 ELRVDLTSTDYDTAADATESSSYFSAQGYLSS-REQEGTESTTDEGQLPQVVEELRDLQV 5271

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
                ++A ++  +   G  +  + WF +G+ + AS  IR      +  LEI+     DSG
Sbjct: 5272 APGTRLAKFQLKV--KGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSG 5329

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNI----------EGLKDGQSAH 3168
             Y+   +N  G A  S +L      +  +KP    H Q +          + +K G S  
Sbjct: 5330 QYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSIT 5389

Query: 3169 FECTV----VPV-----DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
            F   V    VP      ++ +  + W   G      T   +      V+LD+   + H  
Sbjct: 5390 FSVKVEGRPVPTVHWLREEAERGVLWI--GPDTPGYTVASSAQQHSLVLLDVG--RQH-Q 5444

Query: 3220 GEYVCRAYNKYGEDFTRATINCYG 3243
            G Y C A N  G+    A+++  G
Sbjct: 5445 GTYTCIASNAAGQALCSASLHVSG 5468



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 78/357 (21%), Positives = 143/357 (40%), Gaps = 40/357 (11%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S   ++        L+++Q    D+  ++  A    G  + S +L V 
Sbjct: 1381 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVA 1436

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E +      +V        + V   +G    L  +V   +  +V W K+GKK+    + +
Sbjct: 1437 EPK------VVFAKEQPVHREVQAQAGASTTLSCEVAQAQT-EVMWYKDGKKLSFSSKVR 1489

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +     T  L++ +A   D+G+Y C     AG  R      V+ P          KA  A
Sbjct: 1490 MEAVGCTRRLVVQQAGQADAGEYSC----EAGSQRLSFHLHVAEP----------KAVFA 1535

Query: 4622 PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
              +   P   ++ AE G +   SC+ V +    V WYK  K +  S   +M        L
Sbjct: 1536 KEQ---PASREVQAEAGTSATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRL 1591

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ--ADNLPALTPLRDIVVYEGQPA 4738
             + EA   D G+Y C     AG   ++  L V +P    A   PA    R++    G  A
Sbjct: 1592 VVQEAGQADAGEYSC----KAGDQRLSFHLHVAEPKVVFAKEQPA---HREVQAEAGASA 1644

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
                ++ ++ +  + W ++G  +  +   ++   G    L++    + D G ++C A
Sbjct: 1645 TLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA 1700



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 50/222 (22%), Positives = 84/222 (37%), Gaps = 13/222 (5%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            +PP F +++  C     E  +      G P P+I WY++   ++  P    I        
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI+  +   DS  +   A +  G       ++V+          VPP F           
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----------VPPRFVNKVLASPFVE 6121

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLILEAYPQDSGKYE 4585
            G+  +    + G     + W K+G  +    + + L E   G   L+I  A  +D G YE
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            C  +N  G AR  AE  +  P  + + +   +   A  E+ E
Sbjct: 6182 CELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 6223



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 79/361 (21%), Positives = 141/361 (39%), Gaps = 38/361 (10%)

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
            +P   + WY++   + +S   ++        L+++QV   D+  ++  A    G  + S 
Sbjct: 1192 QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSF 1247

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             L + E +       V     L    V   +G    L  +V   +  +V W K+GKK+  
Sbjct: 1248 QLHITEPKA------VFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSS 1300

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
              + +I        L++ +A   D+G+Y C     AG  R      VS P          
Sbjct: 1301 SSKVRIEAAGCMRQLVVQQAGQADAGEYTC----EAGGQRLSFHLDVSEP---------- 1346

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIE-FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675
            KA  A  ++      K+ AE  AI   SC+ V +    V WYK  K +  S   +M    
Sbjct: 1347 KAVFAKEQLAHR---KVQAEAGAIATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRMEAVG 1402

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RDIVVYE 4734
                L + +A   D G+Y C     AG   ++  L V +P          P+ R++    
Sbjct: 1403 CTRRLVVQQACQADTGEYSC----EAGGQRLSFSLDVAEPKVV--FAKEQPVHREVQAQA 1456

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G       ++ ++ +  + W ++G  +  +   +M   G    L++    + D G ++C 
Sbjct: 1457 GASTTLSCEV-AQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQADAGEYSCE 1515

Query: 4795 A 4795
            A
Sbjct: 1516 A 1516



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 82/373 (21%), Positives = 150/373 (40%), Gaps = 54/373 (14%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W + +  +++   + +    TK  L IR + + D+  ++ V     G  + SA L V 
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVC----GQERTSAMLTVR 3622

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
                      +P  FT   +N   T G    L  +++   P++  W K  + ++   R+ 
Sbjct: 3623 A---------LPIKFTEGLRNEEATEGATAVLRCELSKMAPVE--WWKGHETLRDGDRHS 3671

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            + ++     L I     +D+G+Y C+     G+ R  A   V                  
Sbjct: 3672 LRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRA---------------M 3712

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P + IE L+++   EG      C++  K  P V+W KG + ++      + +      L+
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCEL-SKAAP-VEWRKGHETLRDGDRHSLRQDGSRCELQ 3770

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQ 4739
            I      D G+Y CV     G+   +A L V        LPA  +  +++    EG  A 
Sbjct: 3771 IRGLAVVDAGEYSCV----CGQERTSATLTVRA------LPARFIEDVKNQEAREGATAV 3820

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
             + ++ SK  P ++W +    +     + +  +G    L I      DTG ++C      
Sbjct: 3821 LQCEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC----VC 3874

Query: 4800 GQVETSAKLVVKS 4812
            GQ  TSA L V++
Sbjct: 3875 GQERTSATLTVRA 3887



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 61/238 (25%), Positives = 105/238 (44%), Gaps = 15/238 (6%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GF 3477
            APVF   L N E +++G    F+  +T    P+  V W+ +GK L+    +    D  G 
Sbjct: 5125 APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPS--VRWFKDGKLLEEDDHYMINEDQQGG 5181

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIA 3536
              L I+   P D G Y C A N+ G + T A ++V      +  +      + T      
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-----LTSTDYDTAADATESSSYF 5236

Query: 3537 ALEGYSGTVDTLTPEA--ESGNPPEFTTTPSDLILSENSS-AHFECRLIPVNDSSMRVEW 3593
            + +GY  + +    E+  + G  P+      DL ++  +  A F+ ++      + R+ W
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYW 5294

Query: 3594 FHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            F +G+PL   + ++  +      LEI  V + D+G Y    +N  G A  S +L V+G
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 58/219 (26%), Positives = 95/219 (43%), Gaps = 16/219 (7%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            + V + P  FSR L ++ T E   V LEC L       + V W  +G  ++ G     A 
Sbjct: 2159 LVVTELPVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAA 2215

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK-DLILESQHPSGLEKIQ 1422
            +    +L +      D GVY C A     +A +S +++V  +   LI          +IQ
Sbjct: 2216 QGACRSLTIYRCEFADQGVYVCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQ 2271

Query: 1423 YLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK 1482
            ++ + +  +    + E     P  + RP   +  +E      EC+   V+ ++ +V WFK
Sbjct: 2272 FVAENAESRAQLRVKEL----PVTLVRPLRDKIAMEKHRGVLECQ---VSRASAQVRWFK 2324

Query: 1483 NGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
              Q +  G ++  + D  Y  L I D+ AED   YTC A
Sbjct: 2325 GSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 6/133 (4%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD- 3883
            +V  PP+F+ ++ +    E E  +F C +E    P++R  WY++G LL +G++++T+ + 
Sbjct: 6103 LVQVPPRFVNKVLASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 6160

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR-GMKRSE 3941
              G + L I     ED G Y C  VN  G     A +  +  P +  Q Q  R  +  + 
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS-PMLQAQEQCHREQLVAAV 6219

Query: 3942 ALTQMEATIKKYT 3954
             +T+ E  + K T
Sbjct: 6220 EVTEQETKVPKKT 6232



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 50/203 (24%), Positives = 86/203 (42%), Gaps = 12/203 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            E + V LE ++   + PN+ + W K+GV L  G  +         +L+I      D G+Y
Sbjct: 2179 EKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVY 2235

Query: 2716 TCKATNLLGEAVSTASIKIEDRHW-LLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXX 2774
             C A     +A S+AS+K++ R + L+   +  +    I  +                  
Sbjct: 2236 VCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVT 2291

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            + +  L + +  E      EC V  +   + ++ WF  ++ L  G +Y+   D  Y  L 
Sbjct: 2292 L-VRPLRDKIAMEKHRGVLECQVSRA---SAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347

Query: 2835 ITHTYEEDSGIYTCKATNSKGSA 2857
            I+  + ED   YTC A + K SA
Sbjct: 2348 ISDVHAEDEDTYTCDAGDVKTSA 2370



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 78/358 (21%), Positives = 141/358 (39%), Gaps = 38/358 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S   ++        L+++Q    D+  ++  A    G  + S  L V 
Sbjct: 1657 VTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA----GGQRLSFRLHVA 1712

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E   Q              + + V   + + L   +       V WLK+G +++   R++
Sbjct: 1713 ELEPQ------ISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHE 1766

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
               +  T+TL +  A   DS  Y C         R  AE        +D P    + A  
Sbjct: 1767 TASQGDTHTLTVHGAQVLDSAIYSC---------RVGAE-------GQDFPVQVEEVAAK 1810

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
               ++EP+  ++   G  +  +C++       V W  G+   +  K FQM       +L 
Sbjct: 1811 FCRLLEPVCGEL---GGTVTLACEL-SPACAEVVWRCGNTQPRVGKRFQMVAEGPVRSLT 1866

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            +     ED G+Y C + +       +A+L V+ P     +  ++ L  +V  EG  A F+
Sbjct: 1867 VLGLRAEDAGEYVCESRDD----HTSAQLTVSVPRV---VKFMSGLSTVVAEEGGEATFQ 1919

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              + S     + W R+GAL+  +  F +   G +  L I +   ED G  T  A  A+
Sbjct: 1920 C-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGAS 1976



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 59/261 (22%), Positives = 108/261 (41%), Gaps = 29/261 (11%)

Query: 1700 HSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            H++   V+T+ PV F+ P++D+   E +    E  L     P + V WL++GV + A   
Sbjct: 2154 HTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKT 2210

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            +         +L +      D G Y C A +             QS AS++++ +  + +
Sbjct: 2211 MAIAAQGACRSLTIYRCEFADQGVYVCDAHD------------AQSSASVKVQGRTYTLI 2258

Query: 1819 QKIQQLEDSSRYQ-----RREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPD 1873
             +    ED+   Q          ++ V + P  + +        E      EC++     
Sbjct: 2259 YRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSR--- 2315

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             + +V W+   + LQ G +Y   +D  +  L I  V+ ED   YTC A    G   +S +
Sbjct: 2316 ASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQ 2371

Query: 1934 LNVQSKE-SIIRDSQHESALE 1953
              V+ +  +I+R  Q  + +E
Sbjct: 2372 FFVEEQSITIVRGLQDVTVME 2392



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 49/180 (27%), Positives = 78/180 (43%), Gaps = 15/180 (8%)

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            QD + TE     F C ++     EV W +N   + +D  H+I  ++   H L++ ++  +
Sbjct: 2565 QDAEATEEGWASFSCELSHED-EEVEWSLNGMPLYNDSFHEIS-HKGRRHTLVLKSIQRA 2622

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D+G+V    R  S + +   RL V  K  V    F++    L+  E   + L    V  P
Sbjct: 2623 DAGIV----RASSLKVSTSARLEVRVKPVV----FLKALDDLSAEERGTLALQCE-VSDP 2673

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               + W+KDGV + P+ +       G   L +      DA  Y C      GS  TRAR+
Sbjct: 2674 EAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARV 2729



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 60/234 (25%), Positives = 95/234 (40%), Gaps = 8/234 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIV 3340
            P F+T++Q+  ++ +G    F+   V    P   V WF +GK L     Y    D  G  
Sbjct: 5126 PVFLTELQN-QEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400
             L I      + G Y C+A N +G  STKA L+     +   D+             Q  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELR-VDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
              S   ++ T    ++G+ P     L +++       A F+ ++     P L   W+ +G
Sbjct: 5242 LSSR-EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRL--YWFKDG 5298

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            + L A +  R         LEI     EDSG+Y     N  G A ++A + V+G
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 36/122 (29%), Positives = 54/122 (44%), Gaps = 3/122 (2%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
            PP+   K   S   EG DAQF   + G P P++ W+K+G  L   NK + ++        
Sbjct: 6107 PPRFVNKVLASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 6166

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP-TESYVQDQRSQYITDTQQRETEE 381
            L +R   K D G Y     N  G    S  L ++SP  ++  Q  R Q +   +  E E 
Sbjct: 6167 LVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQET 6226

Query: 382  RI 383
            ++
Sbjct: 6227 KV 6228



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 101/402 (25%), Positives = 157/402 (39%), Gaps = 48/402 (11%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLP-LIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            TK+++   V E E   FE     E       W      + +S  FQ      K IL++R+
Sbjct: 2739 TKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVRE 2798

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
                D+     V   RG T+K  A+L+V E+       I+ P   L  Q V       +R
Sbjct: 2799 AAPSDAG--EVVFSVRGLTSK--ASLIVRERP----AAIIKP---LEDQWVAPGEDVELR 2847

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
             +    GT    V+WLK+ K ++   +  ++ E GT  +L++             ++  A
Sbjct: 2848 CELSRAGTP---VHWLKDRKAIRKSQKYDVVCE-GTMAMLVIRG----------ASLKDA 2893

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
            GE  C+ E   S  +   + K     AN   E +  L+  +  +G A+ F+CK    P  
Sbjct: 2894 GEYTCEVEASKSTASLHVEEK-----ANCFTEELTNLQ--VEEKGTAV-FTCK-TEHPAA 2944

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            TV W KG   ++ S   Q S+      L IS     D   Y C      G+    A+L V
Sbjct: 2945 TVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLV 3000

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM-IH 4771
                Q   +  +  L D+ V EG  A F+ +I+      + W  +   +      ++   
Sbjct: 3001 ----QGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQ 3056

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             G   VL +     +D+GT        AG    SA L V  K
Sbjct: 3057 PGGYHVLTLRQLALKDSGTIYFE----AGDQRASAALRVTEK 3094



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 49/189 (25%), Positives = 76/189 (40%), Gaps = 14/189 (7%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS-HRIRTVYAFG 3104
            RPP+F    +++ D +       + +   TG    VI W+ +GK ++   H I      G
Sbjct: 6012 RPPDFE---EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG 6068

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +      DSG Y C A +  G      K+          PRF   +       +G
Sbjct: 6069 SCALILDSLTGVDSGQYMCFAASAAGNCSTLGKI-----LVQVPPRFVNKVL-ASPFVEG 6122

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEY 3222
            + A F CT+     P  +I WY +G  +    + +T+S+   G +VL I      D G Y
Sbjct: 6123 EDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 6180

Query: 3223 VCRAYNKYG 3231
             C   N+ G
Sbjct: 6181 ECELVNRLG 6189



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 59/230 (25%), Positives = 95/230 (41%), Gaps = 8/230 (3%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFV 2566
            P+F   L    E+ +G    ++  V     PS+R  W+ +G  L+    +    D  G  
Sbjct: 5126 PVFLTELQN-QEVQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAM-RPESWEQIQLKEAA 2625
             L I +VV  D G+Y C A N  G                 D A    ES      +   
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 2626 MNKVPEMFVDTGVQ-QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684
             ++  E    T  + Q P     L+   ++  G  +  + Q++ +  P  ++ WFK+G  
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDL-QVAPGTRL-AKFQLKVKGYPAPRLYWFKDGQP 5300

Query: 2685 LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            LT  A ++ T    L TL I S+  +DSG Y    +N +G A S+A + +
Sbjct: 5301 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 53/211 (25%), Positives = 88/211 (41%), Gaps = 10/211 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYV 4031
            P F+T++Q+Q  + +     F+C +   G P   V WF +GK L   + +    D  G  
Sbjct: 5126 PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIRE-- 4089
             +    V P D G Y C A N  G+  TKA ++        YD+       S     +  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-LTSTDYDTAADATESSSYFSAQGY 5241

Query: 4090 MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            + +  Q   E   +E +   P V   L D         A+F  +V G+P PR+ W  +G 
Sbjct: 5242 LSSREQEGTESTTDEGQL--PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQ 5299

Query: 4150 TIVNGSRYKLTYDGMYH-FDIPKTRQYDTGK 4179
             +   +  ++T   + H  +I    + D+G+
Sbjct: 5300 PLTASAHIRMTDKKILHTLEIISVTREDSGQ 5330



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+F           G +  L C++  VG+ T +V W  + +P+  G RFR A + D   
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYR 66

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
            L +L +   DSG Y C+A N +GEA  +  L+V A+     ++ H
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 64/252 (25%), Positives = 101/252 (40%), Gaps = 21/252 (8%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F+ PL ++    E E    E  L+    PN+ V W  +G  L+AG             L 
Sbjct: 2168 FSRPLQDVVTT-EKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGY 3541
            I      D G Y+C A+    +A ++AS+KVQG+   ++  ++     G I  +A  E  
Sbjct: 2224 IYRCEFADQGVYVCDAH----DAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVA--ENA 2277

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
                     E     P        D I  E      EC+   V+ +S +V WF   + L 
Sbjct: 2278 ESRAQLRVKEL----PVTLVRPLRDKIAMEKHRGVLECQ---VSRASAQVRWFKGSQELQ 2330

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ----VKGRQGIIL 3657
             G + + ++D  +  L I  V+  D   YTC A +    A    + Q    V+G Q + +
Sbjct: 2331 PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTV 2390

Query: 3658 EPQLPSHFKSGT 3669
                P+ F+  T
Sbjct: 2391 MEPAPAWFECET 2402



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 33/106 (31%), Positives = 57/106 (53%), Gaps = 3/106 (2%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            APRF+T+      +S G+ A   C+I   P P  +V W  + + + +G R+R + D    
Sbjct: 9    APRFLTRPKAFV-VSVGKDATLSCQIVGNPTP--QVSWEKDQQPVTAGARFRLAQDGDLY 65

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
             L IL +   DSG+Y C+A N +G+A +++ L V ++ +    + H
Sbjct: 66   RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 72/355 (20%), Positives = 139/355 (39%), Gaps = 36/355 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WY++   + +S    +     +  L+++Q    D+  ++   E RG       + + E
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC--EARGQRVSFRLH-ITE 1069

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
             K    +   V       A    + S ++ +  T+VT        W K+GKK+    +  
Sbjct: 1070 PKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVT--------WYKDGKKLSSSSKVG 1121

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +  +  T  L++ +A   D+G+Y C     AG  R      ++ P          K   A
Sbjct: 1122 MEVKGCTRRLVLPQAGKADAGEYSC----EAGGQRVSFHLHITEP----------KGVFA 1167

Query: 4622 PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
              + +    +++ AE G     SC+ V +P   V WYK  K +  S   +M        L
Sbjct: 1168 KEQSVH---NEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRL 1223

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             + +    D G+Y C     AG   V+ +L +T+P        L    ++    G  A  
Sbjct: 1224 VVQQVGKADAGEYSC----EAGGQRVSFQLHITEPKAVFAKEQLVH-NEVRTEAGASATL 1278

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
              ++ ++ +  + W ++G  +  +   ++   G    L++    + D G +TC A
Sbjct: 1279 SCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 143/711 (20%), Positives = 251/711 (35%), Gaps = 54/711 (7%)

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLT 4160
            E + A   P F+  P ++ V EG  A F CRV G P+P V W  +G  +   +G R ++ 
Sbjct: 102  EAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVE 161

Query: 4161 YDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYR---GVLKNAPRP 4216
              G      I   R  D G  EV              L V     D     G    A   
Sbjct: 162  ELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLA 221

Query: 4217 WYDETTQYQRTE--TELEKTFEERQVLQRQGVIDHRPELKPKVIKEP--ETEWQQSVKRK 4272
                  +  R E       +   R     +G       L   V  EP  ET W++  +  
Sbjct: 222  HLQRRREAMRAEGAPASPPSTGTRTCTVTEG---KHARLSCYVTGEPKPETVWKKDGQLV 278

Query: 4273 KNEEYYNKLQELENEQVIKESRLRESTH-QYAIPGDKVTSNTVAKSMAQRYEDNLDQTEE 4331
                 +   ++ +   V+K    ++S    Y      +   T +  +    E  +   + 
Sbjct: 279  TEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKR 338

Query: 4332 VTEQRVQKK--VTQKPRIPDPS-ESTVHGKEVHV-AKQKQTQKEVVGDKEITRKITSTET 4387
            + +  V++K   T    +P PS E+    +E  + A  K   +E   ++ +T +  S + 
Sbjct: 339  LQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADD 398

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
              + +  +T E          +  +  K  +   V   + A F VE    P+  + W R 
Sbjct: 399  DAV-YICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVEL-AVPVGPVHWLRN 456

Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
               +       I    T+  L I Q  +ED    A +A    G  + S    V   R+  
Sbjct: 457  QEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMA----GDCQTSTRFCVSAPRKP- 511

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP--IDVYWLKNGK-KVQPDIRNKILE 4564
               + PP   +      + S  ++       G +P  ID Y ++  K      IR    E
Sbjct: 512  --PLQPPVDPVV--KARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAE 567

Query: 4565 EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD-KPKPQTKAANAPP 4623
               T  L + +   + + ++   A+NS G++       +  P T    PK   +      
Sbjct: 568  WVATPELTVADVAEEGNFQFRVSALNSFGQSP-----YLEFPGTVHLAPKLAVRT----- 617

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
                PLK     EG  + FS  +        +W+   + +K S  +++      +TL I 
Sbjct: 618  ----PLKAVQAVEGGEVTFSVDLT--VASAGEWFLDGQALKASSVYEIHCDRTRHTLTIR 671

Query: 4684 EAFPEDEG-DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
            E      G   K VA      + +  +     P    N P     R+++    + AQ   
Sbjct: 672  EVPASLHGAQLKFVANGIESSIRMEVR---AAPGLTANKPPAAAAREVLARLHEEAQLLA 728

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +++ +    + WL++G  +   P +++       VLL+ +   +D G + C
Sbjct: 729  ELSDQ-AAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 69/275 (25%), Positives = 110/275 (40%), Gaps = 25/275 (9%)

Query: 1974 VVEKP-QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V E P  F +P+++   TE   V LE  L+    P + V W  +G  ++ G         
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQG 2217

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG--LYLDTLDEQRLKKIQE 2090
               +L I      D G Y+C A +A   A    SVKV  ++   +Y   L E    +IQ 
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDAQSSA----SVKVQGRTYTLIYRRVLAEDA-GEIQF 2272

Query: 2091 LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQ 2150
            +   E  +   + +  + PV L      +   E  R   EC+V   +     + WF   Q
Sbjct: 2273 VA--ENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRAS---AQVRWFKGSQ 2327

Query: 2151 KIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILD 2210
            +++ G +Y    D  Y  L I   +AED  TY C A +     V T        ++I + 
Sbjct: 2328 ELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD-----VKTSAQFFVEEQSITI- 2381

Query: 2211 TQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFV 2245
                 GL+ +  +E        E   P + PP+++
Sbjct: 2382 ---VRGLQDVTVMEPAPAWFECETSIPSVRPPKWL 2413



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 4/128 (3%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
            ++P  S  P+F+T+ K+  V   +     C++     P+  + W ++ + + +G R+R  
Sbjct: 2    DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQ--VSWEKDQQPVTAGARFRLA 59

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSE 3941
             D     L IL +   DSG+Y+CRA N  GE F  A +  +   +     Q P  + R  
Sbjct: 60   QDGDLYRLTILDLALGDSGQYVCRARNAIGEAF--AAVGLQVDAEAACAEQAPHFLLRPT 117

Query: 3942 ALTQMEAT 3949
            ++   E +
Sbjct: 118  SIRVREGS 125



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 51/241 (21%), Positives = 103/241 (42%), Gaps = 24/241 (9%)

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            R  NTQ      + ++AE P   +   G  A ++           +Y+ +++   T  ++
Sbjct: 1842 RCGNTQPRVGKRFQMVAEGPVRSLTVLGLRAEDA----------GEYVCESRDDHTSAQL 1891

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
             +S   +  +F+         EG    F C V+      V WF +   ++   + K  ++
Sbjct: 1892 TVSVPRVV-KFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQP--SEKFAIS 1947

Query: 444  ESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +SG +H+L I+++ L D+G +T  A   S   A + R   +  ++ + P+ VE  S++ +
Sbjct: 1948 QSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTL 2007

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             E E        +  P P + W ++   + P   + IH +G    L +     +D  ++ 
Sbjct: 2008 -EVE--------LTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFG 2058

Query: 563  C 563
            C
Sbjct: 2059 C 2059



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 91/404 (22%), Positives = 155/404 (38%), Gaps = 48/404 (11%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFV 3207
            P F T +QN E ++DG    F+C V     P   + W+ +G+ +          D  G  
Sbjct: 5126 PVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQ 3267
             L I      D G Y C A N  G   T+A +       V L S   D+ A   E  S  
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELR------VDLTSTDYDTAADATESSSYF 5236

Query: 3268 GAQQQTPS---------TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEW 3318
             AQ    S         T   + P+ + +++D+      + A F+ ++     P  ++ W
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYW 5294

Query: 3319 FYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            F +G+ L      R      +  L+I+    E+SG+Y    +N +G   + A L      
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL------ 5348

Query: 3379 NLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENA 3438
             L+     P          Q +   M+ R  T  + +KG +  F+V +      R     
Sbjct: 5349 -LVRGPDEPEEKPASDVHEQLVPPRMLER-FTPKKVKKGSSITFSVKVEG----RPVPTV 5402

Query: 3439 HFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAY 3498
            H+   L    +  +     W G      +   +      V+L++     +  G Y C A 
Sbjct: 5403 HW---LREEAERGV----LWIGPDTPGYTVASSAQQHSLVLLDVG---RQHQGTYTCIAS 5452

Query: 3499 NNYGEAVTTASMKVQG-----KRNIILESQLPKGMEGTIDKIAA 3537
            N  G+A+ +AS+ V G     ++  + E+ +   ++GT   I+A
Sbjct: 5453 NAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISA 5496



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 10/146 (6%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FGF 1234
            P FV  +   P V EG++    C +E  G P  ++ W+ +G  +T G++F+T  +   G 
Sbjct: 6108 PRFVNKVLASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQLLED 1293
            + L I  A+  D G Y    VN LGSA  SA +R+             EQ +  +++ E 
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQ 6224

Query: 1294 ---AARRTKQVREDI-TVMQAPQFSR 1315
                 ++T  + E I TV+++P+  R
Sbjct: 6225 ETKVPKKTVIIEETITTVVKSPRGQR 6250



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 43/159 (27%), Positives = 69/159 (43%), Gaps = 9/159 (5%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +   EVTW+ + +++    + K+ V   G    L++     +D+G  +
Sbjct: 1641 GASATLSCEVA-QAQTEVTWYKDGKKLSS--SSKVRVEAVGCTRRLVVQQAGQADAGEYS 1697

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A    G      RL+V E E  ++ +   R   L V+E E ++L A         +TW
Sbjct: 1698 CEA----GGQRLSFRLHVAELEPQISERPCRR-EPLVVKEHEDIILTATLATPSAATVTW 1752

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             KDGV I  +      + G   TL +  A+  D+A Y C
Sbjct: 1753 LKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSC 1791



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 69/302 (22%), Positives = 120/302 (39%), Gaps = 39/302 (12%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT- 4570
            +P  FT   +N     G    L  +++   P++  W K  + ++   R  IL ++GT   
Sbjct: 3448 LPAKFTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCE 3504

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L I      D+G+Y CV     G+ R  A   +                  P   IE +K
Sbjct: 3505 LQICGLAMADAGEYLCVC----GQERTSATLTIRA---------------LPARFIEDVK 3545

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
            ++   EG      C++       V+W KG + ++    + + +   +  L+I      D 
Sbjct: 3546 NQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADT 3603

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G+Y CV     G+   +A L V    +A  +     LR+    EG  A  + ++ SK+ P
Sbjct: 3604 GEYSCV----CGQERTSAMLTV----RALPIKFTEGLRNEEATEGATAVLRCEL-SKMAP 3654

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             ++W +    + +     +  +G    L I     ED G + C      G+  TSA L V
Sbjct: 3655 -VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLC----MCGKERTSAMLTV 3709

Query: 4811 KS 4812
            ++
Sbjct: 3710 RA 3711



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 27/70 (38%), Positives = 40/70 (57%)

Query: 2004 VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            V +PT +V W  + +PV  G RF+   D     L IL     D+G Y+C+A NA+GEA  
Sbjct: 34   VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFA 93

Query: 2064 TSSVKVDAKS 2073
               ++VDA++
Sbjct: 94   AVGLQVDAEA 103



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 5/115 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            VQ  P F   + +    VEG+       +E    P  +I W+K+G  LTTG + ++  + 
Sbjct: 6104 VQVPPRFVNKVLA-SPFVEGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEP 6160

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
              GL+ L I +   +D G+Y C+  N LG A ++A ++I+       E  H + L
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL 6215



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 5/105 (4%)

Query: 763 EEQTSQRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           + Q S  P+F+ RP   +  +  G++A    Q+  V +PT +V W KD +P+TA +R   
Sbjct: 3   QPQFSGAPRFLTRPKAFV--VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFRL 58

Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
             +     L I+ L   D+G Y  RA N +GEA +   ++V A +
Sbjct: 59  AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEA 103



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 4/78 (5%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEY 144
           G +A    ++ GNPTP VSW + + P+    ++ +    Q GD+  L I  +  GD G+Y
Sbjct: 24  GKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLA---QDGDLYRLTILDLALGDSGQY 80

Query: 145 TCTARNQYGEAICSVYIQ 162
            C ARN  GEA  +V +Q
Sbjct: 81  VCRARNAIGEAFAAVGLQ 98



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 40/164 (24%), Positives = 66/164 (40%), Gaps = 7/164 (4%)

Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           D   G   +F+C  T   +  V W+ +  ++       +  +    H L+   VT  D G
Sbjct: 808 DAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEG 866

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
             +C    + GE +   RL V E + V A + + R   L    G    L+       T  
Sbjct: 867 TYSC----RVGEDSVDFRLRVSEPKVVFAKEQLAR-RKLQAEAGASATLSCEVAQAQT-E 920

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           +TW KDG  +  + ++ +   G    L + +A  +DA  Y C A
Sbjct: 921 VTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 36/138 (26%), Positives = 64/138 (46%), Gaps = 6/138 (4%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD- 1498
            V + PRFV +  +    +EG+   F C +E      ++  W+K+G  +T G++F+ + + 
Sbjct: 6104 VQVPPRFVNKVLA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 6160

Query: 1499 -FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLEQIQ 1556
              G + L I     ED G+Y C  VN +G+   S  L  +S           E  +  ++
Sbjct: 6161 RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVE 6220

Query: 1557 VLEDRSKYHRTDMVDEVT 1574
            V E  +K  +  ++ E T
Sbjct: 6221 VTEQETKVPKKTVIIEET 6238



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 79/378 (20%), Positives = 148/378 (39%), Gaps = 33/378 (8%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GL 2699
            AP+F T L++ + + +G  V  +  V  +  P+++  WFK+G  L          D  G 
Sbjct: 5125 APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGG 5181

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE----DRHWLLGESLHPDSLDRIGA 2755
              L I ++   D G+Y C A N +G + + A ++++    D       +         G 
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 5241

Query: 2756 LXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI-HFECNVEPSRDPTLKIEWFFNNK 2814
            L                    +  L ++    G  +  F+  V+    P  ++ WF + +
Sbjct: 5242 LSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGY--PAPRLYWFKDGQ 5299

Query: 2815 PLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFD 2874
            PL +    + T      +L+I     EDSG Y    +N+ G+A +S  L   G       
Sbjct: 5300 PLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG------- 5352

Query: 2875 TQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQ 2934
               P+ K   +  EQ    R+ +   P     +  K    I  + +   VEG+ +     
Sbjct: 5353 PDEPEEKPASDVHEQLVPPRMLERFTP-----KKVKKGSSITFSVK---VEGRPVPTVHW 5404

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            +  + + +  + W     +      + + S     +L L+DV  +  G YTC A N  G+
Sbjct: 5405 L--REEAERGVLW-----IGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457

Query: 2995 AFTSSTVYCTSKDNLIER 3012
            A  S++++ +    + E+
Sbjct: 5458 ALCSASLHVSGLPKVEEQ 5475



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 40/141 (28%), Positives = 67/141 (47%), Gaps = 6/141 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V   P+F   +     VEG +    C ++  G    ++ W+ +G  + TG++F+   E
Sbjct: 6102 ILVQVPPRFVNKVLASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 1365 --FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL-EKI 1421
                 + L + +   ED G+Y C+  N+LG A  S  LR+ +      E  H   L   +
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAV 6219

Query: 1422 QYLE-DTSRYKKTDIIDESVT 1441
            +  E +T   KKT II+E++T
Sbjct: 6220 EVTEQETKVPKKTVIIEETIT 6240



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 83/425 (19%), Positives = 158/425 (37%), Gaps = 53/425 (12%)

Query: 4380 RKITSTETTEIEH---KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            R+  ST T  +     K+++  R+V   +    P + T+ ++P    E +      +F  
Sbjct: 2439 RRTCSTMTGPVHFTVGKSRSSARLVVSDI----PVVLTRPLEPKTGRELQSVVLSCDFRP 2494

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
             P   ++WY+++ P+  S  F++      + L I ++   D+ V+   A    G+A  S 
Sbjct: 2495 AP-KAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSST 2549

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             + VE +     G +         Q+   T         +++  +  +V W  NG  +  
Sbjct: 2550 EVTVEAREVTVTGPL---------QDAEATEEGWASFSCELS-HEDEEVEWSLNGMPLYN 2599

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
            D  ++I  +   +TL++      D+G     ++  +  AR +                  
Sbjct: 2600 DSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVRV--------------- 2644

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
                 P   ++ L D    E   +   C+ V  P   V W K    + PS  +    TA 
Sbjct: 2645 ----KPVVFLKALDDLSAEERGTLALQCE-VSDPEAHVVWRKDGVQLGPSDKYDFLHTAG 2699

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L + +  PED G Y C      G     A+++V       ++     L+ + V EG+
Sbjct: 2700 TRGLVVHDVSPEDAGLYTC----HVGSEETRARVRVHDL----HVGITKRLKTMEVLEGE 2751

Query: 4737 PAQFKTQIT-SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG--TFTC 4793
               F+  ++         W   G  +  +  FQ   +G   +L++      D G   F+ 
Sbjct: 2752 SCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSV 2811

Query: 4794 RATTA 4798
            R  T+
Sbjct: 2812 RGLTS 2816



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            P+ +  P F T  K  + +  G  A    ++  +G+ T +V W KD +PV A +R     
Sbjct: 4    PQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFRLAQ 60

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            +     LTI  + + D+G Y CRA NAIG+A  +  L +  +     ++ H
Sbjct: 61   DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 111/485 (22%), Positives = 188/485 (38%), Gaps = 51/485 (10%)

Query: 922  KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
            +EGG A F+  + P   S + V W +DG  ++ S +     +    +LTI  + + DAG 
Sbjct: 1911 EEGGEATFQCVVSP---SDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ 1967

Query: 982  YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
             T  A  A    ++SA L +     +  +   P  +E+   +      + R   E++ T+
Sbjct: 1968 ITVEAEGA----SSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTR 2022

Query: 1042 KPRFLGPLKGTNKIVEG-------QSAHFEAR----VEPQSDLT---MTVEWYFNGKQIT 1087
                L P K      EG        +  F  R     E   D T   +TVE     +Q+ 
Sbjct: 2023 NATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM----RQVR 2078

Query: 1088 SANRIQTYH--DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSS 1145
                +Q     + G   +++    A+  G +T   R+     Q   +  +  R  + T +
Sbjct: 2079 LVRGLQAVEAREQGTATMEVQLSHADVDGSWT---RDGL-RFQQGPTCHLAVRGPMHTLT 2134

Query: 1146 IHRGLYEKTRHIEESKFVEPMYQIEEISKSKPV-FVQPLSNPPPVSEGKNIHLECRLEPM 1204
            +  GL  +   +   K          +    PV F +PL +    +E + + LEC L   
Sbjct: 2135 LS-GLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVV-TTEKEKVTLECELSR- 2191

Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264
              P + V W  +G  +  G            +L I     AD G Y   A  H   A +S
Sbjct: 2192 --PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDA--H--DAQSS 2245

Query: 1265 AIVRVIERS-DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP-QFSRALHNIET 1322
            A V+V  R+  ++      +   +IQ + + A    Q+R    V + P    R L +   
Sbjct: 2246 ASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLR----VKELPVTLVRPLRDKIA 2301

Query: 1323 VEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGV 1382
            +E     LEC+   V   + +V WF   + ++ G ++    +  Y  L +  V+ ED   
Sbjct: 2302 MEKHRGVLECQ---VSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDT 2358

Query: 1383 YTCQA 1387
            YTC A
Sbjct: 2359 YTCDA 2363



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 89/408 (21%), Positives = 147/408 (36%), Gaps = 57/408 (13%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++P  F + ++   V E   A           P +KW   N  ++    + +        
Sbjct: 3182 ARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLE 3240

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L++R +  +DS  ++       G    SA L V           +P  F    +N   T 
Sbjct: 3241 LVVRNLRPQDSGRYSCSF----GDQTTSATLTVTA---------LPAQFIGKLRNKEATE 3287

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ-DSGKYEC 4586
            G    L  +++ T P++  W K G +   D     L +DG    L +      D+ +Y C
Sbjct: 3288 GATATLRCELSKTAPVE--WRK-GSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC 3344

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            V     GE R  A   +         +P       P   I  L+ +   EG      C++
Sbjct: 3345 VC----GEERTSASLTI---------RPM------PAHFIGRLRHQESIEGATATLRCEL 3385

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
              K  P V+W KG + ++      + +      L+I      D G+Y CV        T+
Sbjct: 3386 -SKAAP-VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATL 3443

Query: 4707 AAKLKVTQPDQADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
              K           LPA     LR+    EG  A    ++ SK+ P ++W +    + + 
Sbjct: 3444 TVKA----------LPAKFTEGLRNEEAVEGATAMLWCEL-SKVAP-VEWRKGPENLRDG 3491

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  EG    L I      D G + C      GQ  TSA L +++
Sbjct: 3492 DRYILRQEGTRCELQICGLAMADAGEYLC----VCGQERTSATLTIRA 3535



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 37/136 (27%), Positives = 64/136 (47%), Gaps = 8/136 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND--FGF 3614
            PP F          E   A F C +       +R  W+ +G  L TG++ +T+++   G 
Sbjct: 6107 PPRFVNKVLASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
            ++L I    + D GLY C+  NR G A  S +L++   Q  +L+ Q   H +    +++ 
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLVAAVEV 6221

Query: 3675 LE-ETLHKREEITIED 3689
             E ET   ++ + IE+
Sbjct: 6222 TEQETKVPKKTVIIEE 6237



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 2/81 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            VS GK+  L C++  +G+PT +V W  + + VT G+RF+   D     L I+     D+G
Sbjct: 21   VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSG 78

Query: 1249 EYTVRAVNHLGSAHTSAIVRV 1269
            +Y  RA N +G A  +  ++V
Sbjct: 79   QYVCRARNAIGEAFAAVGLQV 99



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 2/108 (1%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--H 4460
            G +    PP F  K+      E E A+F    +G P P I+WY++   +     FQ    
Sbjct: 6100 GKILVQVPPRFVNKVLASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              S   +L+IR    ED  ++     NR G+A+ SA L ++    Q +
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQ 6207



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 3/95 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F T  K++   V G+   L  Q+     P  ++ W K+   +T GAR +   D  L 
Sbjct: 9    APRFLTRPKAFVVSV-GKDATLSCQIVGNPTP--QVSWEKDQQPVTAGARFRLAQDGDLY 65

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             L+I  L   DSG Y C+A N +GEA +   ++++
Sbjct: 66   RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 2/104 (1%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F+   K+     G       +I  VG+PT ++ W K+ Q + A +RF          L
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRL 67

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQH 740
            +L L + DSG+Y CRA +A G A     L V   A     + H
Sbjct: 68  TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 57/230 (24%), Positives = 91/230 (39%), Gaps = 19/230 (8%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL--PSGTRYKSTHDFSYVSL 2833
            F+    +I  +EG    F C V  S  P   + W  + + L  P G R +        +L
Sbjct: 112  FLLRPTSIRVREGSEATFRCRVGGSPRPA--VSWSKDGRRLGEPDGPRVRVEELGEASAL 169

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             I      D G Y  +A N  G+A+ + +L    D             A L  +++  EA
Sbjct: 170  RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
              A+G   S P T                + EG+   L   V    +P  +  W  +G++
Sbjct: 230  MRAEGAPASPPSTG----------TRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQL 277

Query: 2954 LEQGSRFKLTSDF--GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + +G R  +  D    FV L ++   + D G+YTC A N  G+ ++S  V
Sbjct: 278  VTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQTYSSVLV 326



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 5/98 (5%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FG 3338
            PP+F+ ++   +  VEG+ A F   +     P ++  W+ +G  L  G++++T  +   G
Sbjct: 6107 PPRFVNKVL-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 6163

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
            +++L I    +E+ G YEC   N+LG     A L+  S
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 58/224 (25%), Positives = 95/224 (42%), Gaps = 20/224 (8%)

Query: 2242 PRFVTELRGTT-HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL--QSAARFHITFDFG 2298
            P F+  LR T+  V EG  A F C+V     P   + +  +G+ L      R  +  + G
Sbjct: 110  PHFL--LRPTSIRVREGSEATFRCRVGG--SPRPAVSWSKDGRRLGEPDGPRVRVE-ELG 164

Query: 2299 YVS-LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELE 2357
              S L I+   P D G Y V+A N LG  ++A ++ V +  +  +          +  L+
Sbjct: 165  EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQ 224

Query: 2358 SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK 2417
                  R E   P +   P  T        + EG+ A   C +   G+P  +  W ++ +
Sbjct: 225  RRREAMRAE-GAPAS---PPSTG--TRTCTVTEGKHARLSCYV--TGEPKPETVWKKDGQ 276

Query: 2418 LIEDSSRITKTHDF--GYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            L+ +  R     D    +V + I   +  D G+Y C ASNL+G+
Sbjct: 277  LVTEGRRHVVYEDAQENFV-LKILFCKQSDRGLYTCTASNLVGQ 319



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 13/212 (6%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P  F  PL+ V   E  K+  E  +     P + + WLK+G  + A        +    S
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACRS 2221

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L +      D G Y C A  A   A  K V   T      R     E    IQ + + ++
Sbjct: 2222 LTIYRCEFADQGVYVCDAHDAQSSASVK-VQGRTYTLIYRRVL--AEDAGEIQFVAENAE 2278

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
             + Q  ++E        +RPL+D   +++ R    E Q   VS  + +V W+K  + +  
Sbjct: 2279 SRAQLRVKELP---VTLVRPLRDKIAMEKHRGV-LECQ---VSRASAQVRWFKGSQELQP 2331

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
              +   + +  Y  L I  + AED  +YT  A
Sbjct: 2332 GPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND--FG 3751
            PPRF  ++  +  V EG    F C +E  G P  +I W+ +G    TG++  TL++   G
Sbjct: 6107 PPRFVNKVLASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 6163

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + L I      D G Y C   N+ GSA  +A++
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAEL 6197



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 10/161 (6%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +P  EVTW+ + +++    + K+ +   G    L++  V  +D+G  +
Sbjct: 1181 GTTAMLSCEVA-QPQTEVTWYKDGKKLSS--SSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A  +    +FQ  L++ E + V A + +   + +    G    L+       T  +TW
Sbjct: 1238 CEAGGQ--RVSFQ--LHITEPKAVFAKEQLVH-NEVRTEAGASATLSCEVAQAQT-EVTW 1291

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             KDG  +  + ++RI   G    L + +A  +DA  Y C A
Sbjct: 1292 YKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 51/200 (25%), Positives = 75/200 (37%), Gaps = 14/200 (7%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR-FTPIYDF 4028
            +Q P F+ +  S       E T F C++   G P   V W  +G+ L   +     + + 
Sbjct: 107  EQAPHFLLRPTSIRVREGSEAT-FRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 4029 GYV-AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKI 4087
            G   A+      P D G Y  RA N  G     A +       +V         +     
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAAL-------VVDSDAADTASRPGTST 216

Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
              + A  Q   E +  E     PP   +     TV EG+ AR  C VTG PKP  +W  +
Sbjct: 217  AALLAHLQRRREAMRAEGAPASPPSTGTR--TCTVTEGKHARLSCYVTGEPKPETVWKKD 274

Query: 4148 GNTIVNGSRYKLTYDGMYHF 4167
            G  +  G R+ +  D   +F
Sbjct: 275  GQLVTEGRRHVVYEDAQENF 294



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 76/280 (27%), Positives = 111/280 (39%), Gaps = 31/280 (11%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKA--GSRFRTFCDF 3475
            +AP F +  ++I  +REG  A F  R+  +  P   V W  +G+ L    G R R     
Sbjct: 108  QAPHFLLRPTSIR-VREGSEATFRCRVGGSPRP--AVSWSKDGRRLGEPDGPRVRVEELG 164

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKI 3535
                L I    P D G Y  RA N  G A   A++ V        ++       GT    
Sbjct: 165  EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS------DAADTASRPGT-STA 217

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A L       + +  E    +PP  +T      ++E   A   C +    +      W  
Sbjct: 218  ALLAHLQRRREAMRAEGAPASPP--STGTRTCTVTEGKHARLSCYV--TGEPKPETVWKK 273

Query: 3596 NGKPLLTGSRVKTINDFGF-VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQG 3654
            +G+ +  G R     D     +L+I    Q D GLYTC A+N  G+ T S  L V     
Sbjct: 274  DGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-TYSSVLVV----- 327

Query: 3655 IILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNP 3694
             + EP +P  FK   + +Q LE  + ++E  T   E P P
Sbjct: 328  -VREPAVP--FK---KRLQDLE--VREKESATFLCEVPQP 359



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 67/288 (23%), Positives = 114/288 (39%), Gaps = 24/288 (8%)

Query: 2941 PDLKIEWYFNGKVLEQ--GSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P   + W  +G+ L +  G R ++        L +     RD G Y  +A N  G A  +
Sbjct: 137  PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
            + +   S  +  +    P GT     + +L+   R+    + +     PP   T      
Sbjct: 197  AALVVDS--DAADTASRP-GTSTAALLAHLQ---RRREAMRAEGAPASPPSTGT---RTC 247

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTT 3116
             ++EG+  H   S   TG+      W  +G+ +    R   VY  A    VL+IL  K +
Sbjct: 248  TVTEGK--HARLSCYVTGEPKPETVWKKDGQLVTEGRR-HVVYEDAQENFVLKILFCKQS 304

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G Y+C A+N  GQ   SV +   + +   K R    +Q++E +++ +SA F C    V
Sbjct: 305  DRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKR----LQDLE-VREKESATFLC---EV 356

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              P  +  W+     +  S +     +     L +      D   Y+C
Sbjct: 357  PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC 404



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 73/320 (22%), Positives = 126/320 (39%), Gaps = 35/320 (10%)

Query: 2993 GEAFTSSTVY---CTSKDNLIERTQHPKGTEG--LEKIQN-LEDSLRKEPGQQPDDDTGR 3046
            G+A  +S+VY   C    + +   + P    G  L+ + N +E S+R E    P     +
Sbjct: 648  GQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANK 707

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPT-GDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP      ++++        H EA L+    DQ+  + W  +G+T+    +     + G 
Sbjct: 708  PP--AAAAREVL-----ARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGR 760

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
             VL +      D+G Y C   ++ G+    + ++ + +    K    + +  +     G 
Sbjct: 761  RVLLVRDVARDDAGLYEC--VSRGGRIAYQLSVQGLARFL-HKDMAGSCVDAVA----GG 813

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYT-QNHDSGEYVC 3224
             A FEC      +  + + WY +G  + HS       D G     +A T    D G Y C
Sbjct: 814  PAQFEC---ETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            R     GED     +       V+ +    + LA+ R+L++  GA   T S   A+    
Sbjct: 871  RV----GEDSVDFRLRVSEPKVVFAK----EQLAR-RKLQAEAGA-SATLSCEVAQAQTE 920

Query: 3285 ITQIQDVTKLVEGQSAHFEA 3304
            +T  +D  KL        EA
Sbjct: 921  VTWYKDGKKLSSSSKVCMEA 940



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 50/198 (25%), Positives = 77/198 (38%), Gaps = 9/198 (4%)

Query: 2007 PTMRVEWYCNGRPVQQ--GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            P   V W  +GR + +  G R +        AL I  A   D GTY  +A N +G A   
Sbjct: 137  PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196

Query: 2065 SSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEG 2124
            +++ VD+ +              +  L++  R     E  P   P   +  T    + EG
Sbjct: 197  AALVVDSDAADTASRPGTSTAALLAHLQR-RREAMRAEGAPASPP---STGTRTCTVTEG 252

Query: 2125 DRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY-VALDILYTYAEDSGTYM 2183
              A   C V    +P     W  +GQ +  G R+    D      L IL+    D G Y 
Sbjct: 253  KHARLSCYVT--GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYT 310

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C A+N +G+  ++  + V
Sbjct: 311  CTASNLVGQTYSSVLVVV 328



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 99/470 (21%), Positives = 185/470 (39%), Gaps = 65/470 (13%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            V+W +    L   +K  M     T    L++ Q G  D GEY+C A  Q       +  +
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTR--RLVLPQAGKADAGEYSCEAGGQRVSFHLHI-TE 1161

Query: 163  PEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR-QTQKVAYTNGTDHSSTDDF 221
            P+G              + V   V+ +A  T   + E ++ QT+   Y +G   SS+   
Sbjct: 1162 PKGVFAKE---------QSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKV 1212

Query: 222  KVDTFEYRLLREVSFRESITKRYVGESDVQISTE-IDRSLGPVSPPKIAQKPR----NSK 276
            +++       R +  ++ + K   GE   +   + +   L    P  +  K +      +
Sbjct: 1213 RMEV--KGCTRRLVVQQ-VGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVR 1269

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             + GA A    +++   +  VTW+K+G++L +S+K  I        L V+   ++D+G Y
Sbjct: 1270 TEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T  A    G    S +L V  P   + ++Q +             +++    A+A    +
Sbjct: 1329 TCEA----GGQRLSFHLDVSEPKAVFAKEQLA-----------HRKVQAEAGAIATLSCE 1373

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNV 455
            V Q +  TE                 VTW+ + +++    + K+ +   G    L++   
Sbjct: 1374 VAQAQ--TE-----------------VTWYKDGKKLSS--SSKVRMEAVGCTRRLVVQQA 1412

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
              +D+G  +C    ++G       L+V E  +VV  K       +  + G    L+    
Sbjct: 1413 CQADTGEYSC----EAGGQRLSFSLDVAE-PKVVFAKEQPVHREVQAQAGASTTLSCEVA 1467

Query: 516  GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
               T  + W KDG  +  + ++R+   G    L + +A  +DA  Y C A
Sbjct: 1468 QAQT-EVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQADAGEYSCEA 1516



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 4/147 (2%)

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
            D+ T    + ++++  +   AA +  +VR+++   + P FS    + E   G  + LEC 
Sbjct: 4861 DLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECV 4920

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTG-HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            +    D  +R  W  +G  +  G H           +L +  +   D+G YTCQ +N+ G
Sbjct: 4921 VASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCSLLIAGLDRADAGCYTCQVSNKFG 4978

Query: 1393 EAVTSCALRVIAKKDLILESQHPSGLE 1419
            + VT  A  V++  +   ES     L+
Sbjct: 4979 Q-VTHSACVVVSGSESEAESSSGGELD 5004



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 47/225 (20%), Positives = 91/225 (40%), Gaps = 19/225 (8%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL------VECNKYSMRYNE 124
            PP   + F   +  +G +  F  K+ G P P V W R++A         +   Y++  + 
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184
            Q    SL++  +G   +G YTC A N  G+A+CS  +   G                   
Sbjct: 5430 QQH--SLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFL 5487

Query: 185  TVEHKAYGTQGYTTEQ------SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE 238
                +A   QG+ T         R+ + +A      H S  +   + F  +L  +++  E
Sbjct: 5488 QGTTQAISAQGFQTASFADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQKLTSQIT--E 5545

Query: 239  SITKRYVGESDVQI--STEIDRSLGPVSPPKIAQKPRNSKLQEGA 281
             ++ + + ++ +Q+      + S  P + P+  +   +S +QE +
Sbjct: 5546 MVSAK-ITQAKLQVPGGDSDEDSKTPSASPRHGRSRPSSSIQESS 5589



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            +++ Q    P FLT   +   +  G  A   C++  + +P   + W  + Q + AG R+R
Sbjct: 1    MDQPQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFR 57

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               D     L IL     DSG Y+C+A N +GEA     L+V
Sbjct: 58   LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 43/204 (21%), Positives = 82/204 (40%), Gaps = 11/204 (5%)

Query: 364  QDQRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            Q    +Y  +   +     + ++E KA+  +     ++     G      C V  +   E
Sbjct: 1506 QADAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTE 1564

Query: 423  VTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            VTW+ + +++    + K+ +   G    L++     +D+G  +C    K+G+      L+
Sbjct: 1565 VTWYKDGKKLSS--SSKVRMEAVGCTRRLVVQEAGQADAGEYSC----KAGDQRLSFHLH 1618

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V E + V A K       +    G    L+       T  +TW KDG  +  + ++R+  
Sbjct: 1619 VAEPKVVFA-KEQPAHREVQAEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRVEA 1676

Query: 542  DGGASTLDIPRAKASDAAWYQCTA 565
             G    L + +A  +DA  Y C A
Sbjct: 1677 VGCTRRLVVQQAGQADAGEYSCEA 1700



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 83/400 (20%), Positives = 150/400 (37%), Gaps = 50/400 (12%)

Query: 4416 KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFV 4475
            + +P  V EHE               + W ++   I+ S   +  +      L +    V
Sbjct: 1724 RREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQV 1783

Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
             DSA+++     R G       + VEE         V   F    + V    G  V L  
Sbjct: 1784 LDSAIYSC----RVGAEGQDFPVQVEE---------VAAKFCRLLEPVCGELGGTVTLAC 1830

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            +++     +V W     + +   R +++ E    +L +L    +D+G+Y C     + + 
Sbjct: 1831 ELSPACA-EVVWRCGNTQPRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVC----ESRDD 1885

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
               A+  VS+P                 + +  L   +  EG    F C +V      V 
Sbjct: 1886 HTSAQLTVSVPRVV--------------KFMSGLSTVVAEEGGEATFQC-VVSPSDVAVV 1930

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            W++   L++PS+ F +S++   ++L IS+   ED G     A  ++     +A L+V + 
Sbjct: 1931 WFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASS----SAALRVRE- 1985

Query: 4716 DQADNLPAL--TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
                  P L    L    V E      + ++T +  P ++W R    +    + ++  EG
Sbjct: 1986 -----APVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEG 2039

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                L++ N    D G F C         +T AKL V+ +
Sbjct: 2040 ARHRLVLHNVGFADRGFFGCETP----DDKTQAKLTVEMR 2075



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 58/269 (21%), Positives = 102/269 (37%), Gaps = 33/269 (12%)

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  V W K+   + P  + K+  E     L IL   P D+G Y C     AG A    E 
Sbjct: 2496 PKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC----QAGSAHSSTEV 2551

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V                     +  PL+D    E     FSC++  +    V+W     
Sbjct: 2552 TVEAREV---------------TVTGPLQDAEATEEGWASFSCELSHED-EEVEWSLNGM 2595

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +    + ++S     +TL +      D G    +   S+ +V+ +A+L+V    +   +
Sbjct: 2596 PLYNDSFHEISHKGRRHTLVLKSIQRADAG----IVRASSLKVSTSARLEV----RVKPV 2647

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L  L D+   E      + ++ S  +  + W ++G  +  +  +  +H      L++ 
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVH 2706

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED G +TC      G  ET A++ V
Sbjct: 2707 DVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 15/187 (8%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F++  Q ++V EG      C ++ R    V W     Q+     ++ +V +     L++
Sbjct: 3980 RFLRELQHQEVDEGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQ-MVQDGAAAELLV 4037

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
              V   D+G  TC     +G T     L+V    +V  PKF  R  +L    G+   L  
Sbjct: 4038 RGVEQEDAGDYTC----DTGHTQSMASLSV----RVPRPKFKTRLQSLEQETGDIARLCC 4089

Query: 513  RAVGTPTPRIT-WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +     +  +  W K+GV +   P+  + + G    L I + +A D   Y C    V G 
Sbjct: 4090 QLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC----VTGG 4145

Query: 572  TATRARL 578
              T A L
Sbjct: 4146 QKTAASL 4152



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 64/239 (26%), Positives = 88/239 (36%), Gaps = 22/239 (9%)

Query: 768  QRPQFI-RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI-TASSRITSIFNF 825
            Q P F+ RP      ++EG  A F  ++     P   V W KDGR +         +   
Sbjct: 108  QAPHFLLRPTSI--RVREGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEEL 163

Query: 826  GYVS-LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKT 884
            G  S L I   R  D G+Y VRA N LG A + A++ V + +  TA       R      
Sbjct: 164  GEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTAS------RPGTSTA 217

Query: 885  XXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVE 944
                              P S      +T      ++ EG  A     +   G+      
Sbjct: 218  ALLAHLQRRREAMRAEGAPASPPSTGTRT-----CTVTEGKHARLSCYVT--GEPKPETV 270

Query: 945  WLKDGRPVEASSRITTFFNFGY-VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDG+ V    R   + +      L I      D G YTC A N +GQ T S+ L +V
Sbjct: 271  WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-TYSSVLVVV 328



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 3/90 (3%)

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            SA+ EV  +  VF   + D+   E      +     V DP+  V W ++GV +  S++  
Sbjct: 2637 SARLEVRVKPVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYD 2693

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
             +H  G   L +  V+PED+G YTC   +E
Sbjct: 2694 FLHTAGTRGLVVHDVSPEDAGLYTCHVGSE 2723



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 5/137 (3%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--R 690
            V  PP+F+  + +   +EG    F   IE  G P  +I W K+G  +   ++F ++   R
Sbjct: 6104 VQVPPRFVNKVLASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPR 6161

Query: 691  FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQHPETLQYIQQ 749
             G + L + + + +D G Y C  V+  G A   A L + +P    +      + +  ++ 
Sbjct: 6162 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEV 6221

Query: 750  LEDYSKYQHQESIEEQT 766
             E  +K   +  I E+T
Sbjct: 6222 TEQETKVPKKTVIIEET 6238



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSG 3491
            EGE+A F   +     P ++  WY +G  L  G++F+T  +   G ++L I     ED G
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 3492 EYLCRAYNNYGEAVTTASMKVQ 3513
             Y C   N  G A  +A +++Q
Sbjct: 6179 LYECELVNRLGSARASAELRIQ 6200



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 54/215 (25%), Positives = 87/215 (40%), Gaps = 12/215 (5%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            VT  P   +RP       E + V  EC+L   +  N+ V W K+G  +  G         
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQG 2217

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559
               +L I      D G+Y C A +       S ++  R+ T I R    E   E IQ + 
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHD--AQSSASVKVQGRTYTLIYRRVLAEDAGE-IQFVA 2274

Query: 1560 DRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKP 1619
            + ++      V E+    P+  T ++ +  K     H       VS A+ +V W+  ++ 
Sbjct: 2275 ENAESRAQLRVKEL----PV--TLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQE 2328

Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
            L+ G ++   ++  +  L I     ED  TYTC A
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 56/237 (23%), Positives = 95/237 (40%), Gaps = 21/237 (8%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++V  E + +  EC  E SR P + + W  +   L +G         +  SL I
Sbjct: 2168 FSRPLQDVVTTEKEKVTLEC--ELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                  D G+Y C A +++ SA+     R      + +     +    ++ V +  E+R 
Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQGRTY---TLIYRRVLAEDAGEIQFVAENAESR- 2280

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLE 2955
            A+ R   +P T        I +     ++E QV     QV           W+   + L+
Sbjct: 2281 AQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVR----------WFKGSQELQ 2330

Query: 2956 QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
             G +++L SD  +  L + DV+  D   YTC A    G+  TS+  +   +   I R
Sbjct: 2331 PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEEQSITIVR 2383



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 39/163 (23%), Positives = 71/163 (43%), Gaps = 12/163 (7%)

Query: 1701 SAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            S   +++ Q P  F   +      E + A F   +   G P  ++ W ++G  +   N+ 
Sbjct: 6097 STLGKILVQVPPRFVNKVLASPFVEGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKF 6154

Query: 1760 TTMHD--FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH-ES 1816
             T+ +   G + L ++  + ED G Y C  +N LG A  S+ L +QS      E  H E 
Sbjct: 6155 QTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQ 6214

Query: 1817 ALQKIQQLEDSSRYQRR----EDVEVAVNQAPRFITQLNGPTK 1855
             +  ++  E  ++  ++    E+    V ++PR   Q   P+K
Sbjct: 6215 LVAAVEVTEQETKVPKKTVIIEETITTVVKSPR--GQRRSPSK 6255



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/112 (26%), Positives = 57/112 (50%), Gaps = 4/112 (3%)

Query: 2234 VEEPKIS-PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292
            +++P+ S  PRF+T  +    V  GK A   CQ+  V +P  ++ +  + + + + ARF 
Sbjct: 1    MDQPQFSGAPRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFR 57

Query: 2293 ITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344
            +  D     L I      D+G+Y  +A NA+G   +A+ + V A+ +   ++
Sbjct: 58   LAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA 109



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 18/195 (9%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            ++ +AL  +F++  ++++  EG      C ++ +  P V W      +R    + +   +
Sbjct: 3795 LTVRALPARFIEDVKNQEAREGATAVLQCELS-KAAP-VEWRKGSETLRGGDRYSL--RQ 3850

Query: 445  SGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
             G    L I  ++++D+G  +CV     G+      L V    +   P F E   +L   
Sbjct: 3851 DGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTV----RAPQPVFREPLQSLQAE 3902

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            EG    L    +  PT  + W K G+ +  N        G  + L +   +  D   Y C
Sbjct: 3903 EGSTATLQCE-LSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC 3961

Query: 564  TAQNVAGSTATRARL 578
            T     GS AT A L
Sbjct: 3962 T----CGSQATSATL 3972



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 38/137 (27%), Positives = 62/137 (45%), Gaps = 8/137 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FG 2298
            PPRFV ++  +  V EG+ A F C +E    P +R  +Y +G  L +  +F    +   G
Sbjct: 6107 PPRFVNKVLASPFV-EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 6163

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL---EKIRE 2355
             + L I+    ED G Y  + +N LG   ++  + + +      E    E L    ++ E
Sbjct: 6164 LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 6223

Query: 2356 LESAEPFKRPEIPEPVT 2372
             E+  P K   I E +T
Sbjct: 6224 QETKVPKKTVIIEETIT 6240



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSG 2180
            EG+ A F C +E    P+  I W+ +G  +  G++++T  +   G + L I     ED G
Sbjct: 6121 EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
             Y C+  N+LG A  +  L++
Sbjct: 6179 LYECELVNRLGSARASAELRI 6199



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 2/105 (1%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F    K   V+  + A    ++  VG+P  +V W ++  P+ A  R     D     
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYR 66

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814
            L +  +   DSG Y CRA N +GEA  +  L V ++A+   ++ H
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 56/218 (25%), Positives = 79/218 (36%), Gaps = 13/218 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKM--GSRFRTTHDFGFVTLDINSVVANDAG 2579
            EG  A +  RV   G P     W  +G  L    G R R         L I +    D G
Sbjct: 123  EGSEATFRCRVG--GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG 180

Query: 2580 LYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQ 2639
             Y  +A N  G                 D A RP +     L  A + +  E     G  
Sbjct: 181  TYEVRAENPLGAASAAAALVVDSDAA--DTASRPGTSTAALL--AHLQRRREAMRAEGAP 236

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
             +P  T        + EG+H  L   V    +P  +  W K+G  +T G R     D   
Sbjct: 237  ASPPSTGTRTC--TVTEGKHARLSCYVTG--EPKPETVWKKDGQLVTEGRRHVVYEDAQE 292

Query: 2700 -VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               L I   +  D G+YTC A+NL+G+  S+  + + +
Sbjct: 293  NFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 58/217 (26%), Positives = 97/217 (44%), Gaps = 28/217 (12%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA---NL 999
            V WLKDG  + A   +         +LTI      D G Y C A++A   A+        
Sbjct: 2196 VRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTY 2255

Query: 1000 TIVTKKDIIAESQHPGGLEKIQYL-EDASRYSKRTEEEVKITQKPRFLGPLKGTNKI-VE 1057
            T++ ++ ++AE        +IQ++ E+A   ++   +E+ +T     + PL+  +KI +E
Sbjct: 2256 TLIYRR-VLAED-----AGEIQFVAENAESRAQLRVKELPVT----LVRPLR--DKIAME 2303

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
                  E +V   S  +  V W+   +++    + +   D  Y  L I+ V AED   YT
Sbjct: 2304 KHRGVLECQV---SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYT 2360

Query: 1118 VVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKT 1154
                  AG+ + SA   VE +S     +I RGL + T
Sbjct: 2361 C----DAGDVKTSAQFFVEEQS----ITIVRGLQDVT 2389



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP   T  K   +  G+ A    ++  V + T +V W  + +P+ +G+RF    +     
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYR 66

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEA 1661
            L I+     DSG Y CRA NA+GEA
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEA 91



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 43/198 (21%), Positives = 81/198 (40%), Gaps = 11/198 (5%)

Query: 370  YITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            Y  + + +    R+ I+E K +  +   V  +     G      C V  +   EVTW+ +
Sbjct: 1052 YSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVA-QAQTEVTWYKD 1110

Query: 429  DRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
             +++    + K+ +   G    L++     +D+G  +C A    G       L++ E + 
Sbjct: 1111 GKKLSS--SSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA----GGQRVSFHLHITEPKG 1164

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
            V A K     + +    G   +L+   V  P   +TW KDG  +  + ++R+   G    
Sbjct: 1165 VFA-KEQSVHNEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRR 1222

Query: 548  LDIPRAKASDAAWYQCTA 565
            L + +   +DA  Y C A
Sbjct: 1223 LVVQQVGKADAGEYSCEA 1240



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 55/235 (23%), Positives = 98/235 (41%), Gaps = 15/235 (6%)

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            L   P   +V+ G       ++ + +D+ + Y  D    +T  +  + E+++    V+  
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDT-YTCDAGDVKTSAQFFVEEQSIT--IVRGL 2385

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            QD  V E     F+C  +        W +    ++   N   L  E   H LM+     +
Sbjct: 2386 QDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVG-LEQEGTVHRLMLRRTCST 2444

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
             +G V        G++    RL V+    VV  + +E  +    RE + VVL+      P
Sbjct: 2445 MTGPVHFTV----GKSRSSARL-VVSDIPVVLTRPLEPKTG---RELQSVVLSCDF--RP 2494

Query: 519  TPR-ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
             P+ + W KD  P+ P+ + ++  +G  + L I R   +DA  Y+C A +   ST
Sbjct: 2495 APKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSST 2549



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-F 691
            V+ PP F   L   TA  G  +    R+   G P   I W K+G++++       I    
Sbjct: 6010 VWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPD 6067

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
            G  +L + SL   DSG+Y C A SA G   T  K ++ V PR
Sbjct: 6068 GSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPR 6109



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 5/115 (4%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ +   PRF+  +  +   VEG+ A F   +E        + WY +G  +T+ N+ QT 
Sbjct: 6101 KILVQVPPRFVNKVLAS-PFVEGEDAQFTCTIEGAP--YPQIRWYKDGALLTTGNKFQTL 6157

Query: 1096 HD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             +   G + L I +   ED G+Y     N  G A+ SA + +++         HR
Sbjct: 6158 SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 6212



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            PRF    K  + V  G      C++  VG+PT ++ W  + +P   G+R     D     
Sbjct: 10   PRFLTRPKAFV-VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYR 66

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            L I  +   D+G+Y CRA N  G A     +   A+
Sbjct: 67   LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P F++ P A  V  G+ A   C++ G+P P+V W  +   +  G+R++L  DG +Y   I
Sbjct: 10   PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTI 69

Query: 4170 PKTRQYDTGK 4179
                  D+G+
Sbjct: 70   LDLALGDSGQ 79



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 54/238 (22%), Positives = 94/238 (39%), Gaps = 23/238 (9%)

Query: 1573 VTTQAPIC-TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631
            V T+ P+  +  L++V   E ++   E  L   S   + V W  +   L++G        
Sbjct: 2160 VVTELPVSFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGVELRAGKTMAIAAQ 2216

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691
                +L I  C   D G Y C A +A             S  S+ ++ +    + R    
Sbjct: 2217 GACRSLTIYRCEFADQGVYVCDAHDA------------QSSASVKVQGRTYTLIYRRVLA 2264

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLI---PVGDPKLRVEWLR 1748
            ED  + Q  +   E   Q  V  +P+  +R   ++ A  + R +    V     +V W +
Sbjct: 2265 EDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFK 2324

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
                ++   +   + D  Y  L +  V+ ED  TYTC A    G+  TS+  FV+ ++
Sbjct: 2325 GSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEEQS 2378



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/350 (21%), Positives = 129/350 (36%), Gaps = 24/350 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P  +TRP   +   E Q V   C   P   +   V+W+K+  P++   +F+   +     
Sbjct: 2468 PVVLTRPLEPKTGRELQSVVLSCDFRPAPKA---VQWYKDDTPLSPSEKFKMSLEGQMAE 2524

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L I+ L+  D+G+Y C+A +   + EV+  +  R  T +    Q+    E+         
Sbjct: 2525 LRILRLMPADAGVYRCQAGSAHSSTEVT--VEAREVT-VTGPLQDAEATEEGWASFSCEL 2581

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
             H  + V+      P+   S   +  K G+R     + I  +DA   +    + K   S 
Sbjct: 2582 SHEDEEVEWSLNGMPLYNDSFHEISHK-GRRHTLVLKSIQRADA--GIVRASSLKVSTSA 2638

Query: 1624 SRFTETNNFGFV-ALDIMSCLPEDSGTYTCRAINALGEAV--TSGIAIVHSKKSIYLESQ 1680
                      F+ ALD +S     +    C   +     V    G+ +  S K  +L + 
Sbjct: 2639 RLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTA 2698

Query: 1681 -HEGALPRLNQLEDTSKYQRHSAQDEVITQAPV------FTMPMKDIRVAENQAAHFEAR 1733
               G +      ED   Y  H   +E   +  V       T  +K + V E ++  FE  
Sbjct: 2699 GTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECV 2758

Query: 1734 LI--PVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSG 1781
            L      DP +   W   G  + +S+R           L ++   P D+G
Sbjct: 2759 LSHESASDPAM---WTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG 2805



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 10/120 (8%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            AA +GY      +  E +    P F+ T  D       +   EC  +  + + +R  W  
Sbjct: 4881 AAFKGYK-----VRKEMKQQEGPMFSHTFGDTEAQVGDALRLEC--VVASKADVRARWLK 4933

Query: 3596 NGKPLLTGSR--VKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G  L  G    +  + D G   L I G+ + DAG YTC+ +N+ G+ T S  + V G +
Sbjct: 4934 DGVELTDGRHHHIDQLGD-GTCSLLIAGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSE 4992



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F    +N     G    F+  + G P P V W  K   L+E + + M   +Q G   L
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWF-KDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 132  LIKQIGPGDEGEYTCTARNQYG 153
            +I  + P D G Y C A N  G
Sbjct: 5185 IITAVVPADMGVYRCLAENSMG 5206



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 113/481 (23%), Positives = 190/481 (39%), Gaps = 51/481 (10%)

Query: 1998 EATLTPVNDPT-MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
            EAT   V  P+ + V W+ +G  +Q   +F  +      +L I     ED G    +A  
Sbjct: 1915 EATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG 1974

Query: 2057 AVGEA-VTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKP-------IEEEQPGQR 2108
            A   A +      V  K  L   T++E R     E+E   RP P            PG+ 
Sbjct: 1975 ASSSAALRVREAPVLFKKKLEPQTVEE-RSSVTLEVE-LTRPWPELRWTRNATALAPGKN 2032

Query: 2109 PVFLTALTS-----LENLKEGDRAHFECRV-EPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
             V + A  +     L N+   DR  F C   +      LT++      ++  G +     
Sbjct: 2033 -VEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEM--RQVRLVRGLQAVEAR 2089

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII-LDTQHP--NGLEK 2219
            + G   +++  ++A+  G++         +   TC L V G  + + L    P  +GL  
Sbjct: 2090 EQGTATMEVQLSHADVDGSWTRDGLRF--QQGPTCHLAVRGPMHTLTLSGLRPEDSGL-M 2146

Query: 2220 IRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
            + + E    S R+ V E  +S  R + ++  T    E +    EC++     PN+ + + 
Sbjct: 2147 VFKAEGVHTSARLVVTELPVSFSRPLQDVVTT----EKEKVTLECELSR---PNVDVRWL 2199

Query: 2280 HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKG- 2338
             +G  L++     I       SL I  C   D G Y   A +A     S+ S+ V  +  
Sbjct: 2200 KDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTY 2255

Query: 2339 SIISESQRPEGLEKIREL-ESAEPFKRPEIPE-PVTRQRPVFTQPLQNIDNI-QEGQTAH 2395
            ++I      E   +I+ + E+AE   +  + E PVT  RP+        D I  E     
Sbjct: 2256 TLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLR-------DKIAMEKHRGV 2308

Query: 2396 FDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
             +C+   V   + +V WF+  + ++   +     D  Y  + IS V  EDE  Y C A +
Sbjct: 2309 LECQ---VSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD 2365

Query: 2456 L 2456
            +
Sbjct: 2366 V 2366



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 8/109 (7%)

Query: 635  PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            P P F  PL+S+ A EG     +  +    +PT  + W K G  ++A+ R     +    
Sbjct: 3888 PQPVFREPLQSLQAEEGSTATLQCELS---EPTATVVWSKGGLQLQANGRREPRLQGCTA 3944

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR-ATIERTSQHPE 742
             L +  L  +D+GEYTC      G   T A L VT       R  QH E
Sbjct: 3945 ELVLQDLQREDTGEYTC----TCGSQATSATLTVTAAPVRFLRELQHQE 3989



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 26/92 (28%), Positives = 42/92 (45%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F      + F +G +A+F   + G P P + W +  A L   NK+      ++G + 
Sbjct: 6107 PPRFVNKVLASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 6166

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            L+I+     D G Y C   N+ G A  S  ++
Sbjct: 6167 LVIRAASKEDLGLYECELVNRLGSARASAELR 6198



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 78/397 (19%), Positives = 152/397 (38%), Gaps = 37/397 (9%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            E  +K +      + ++     E  +A FE +     +    W  ++ P++ S + ++  
Sbjct: 4331 EAQLKVTAKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVRTSENAEVVF 4390

Query: 4462 FST--KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            F    + +L+++ +  +DS     +A    G    SA L V   R +    I+ P     
Sbjct: 4391 FENGLRHLLLLKNLRPQDSCRVTFLA----GDMVTSAFLTVRGWRLE----ILEP----- 4437

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTY-TLLILEAY 4577
             +N  V +G   R    ++   P+ +  W  NG  VQPD  +  +  DG++  LL+  A 
Sbjct: 4438 LKNAAVRAGAQARFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHQALLLRSAQ 4497

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
            P  +G+      ++   AR     V+ LP   D P+     A++   +        +++G
Sbjct: 4498 PHHAGEVTFACRDAVASARL---TVLGLP---DPPEDAEVVAHSSHTVTLSWAAP-MSDG 4550

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIK-PSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
                   ++  K   T QW    +L+  P          + Y  R++   P   G+    
Sbjct: 4551 GGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGE---- 4606

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
              +    V +A   K   P      P+    R +    G+    + ++ ++    I W +
Sbjct: 4607 PVHLPQTVRLAEPPKPVPPQ-----PSAPESRQVAA--GEDVSLELEVVAEAGEVI-WHK 4658

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                I     F+++ +G   +L+I     ED G + C
Sbjct: 4659 GMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 2/72 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +  G+ A   C++  VG+PT +V W ++++ +   +R     D     +TI  +   D G
Sbjct: 21   VSVGKDATLSCQI--VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSG 78

Query: 2448 VYMCRASNLLGE 2459
             Y+CRA N +GE
Sbjct: 79   QYVCRARNAIGE 90



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 22/76 (28%), Positives = 39/76 (51%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            +P  ++ W  + + +  G+RF+L  D     L ++D+   DSG Y C+A N  GEAF + 
Sbjct: 36   NPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95

Query: 3000 TVYCTSKDNLIERTQH 3015
             +   ++    E+  H
Sbjct: 96   GLQVDAEAACAEQAPH 111



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN------FPIKNSPDFQIHTFS 4463
            PP   ++  P +V +     F V+ +G P+P + W RE       +   ++P + + + +
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +  L++  V  +    +  +A N  G A CSA+L V
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 11/146 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R         L +      D+G YSC A    G   +S +L   
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSFQLHIT 1252

Query: 3142 D-KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            + K+   K +    + N    + G SA   C V        ++ WY +G+ +  S++++ 
Sbjct: 1253 EPKAVFAKEQL---VHNEVRTEAGASATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRI 1306

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             +      L +      D+GEY C A
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYTCEA 1332



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 4/81 (4%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN--FGYVSLNIMHLRAEDAG 841
            EG +A F   +     P +R  WYKDG  +T  ++  ++     G + L I     ED G
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 842  SYTVRAVNKLGEAISTASIRV 862
             Y    VN+LG A ++A +R+
Sbjct: 6179 LYECELVNRLGSARASAELRI 6199



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 66/294 (22%), Positives = 104/294 (35%), Gaps = 34/294 (11%)

Query: 82  RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGD 140
           R  +G  A F  ++ G+P P VSW++    L E +   +R  E+ G+ S L I+   P D
Sbjct: 120 RVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRV-EELGEASALRIRAARPRD 178

Query: 141 EGEYTCTARNQYGEAICSVYIQPEGXXXXXXX---XXXXXXYRHVSETVE---------- 187
            G Y   A N  G A  +  +  +                   H+    E          
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPAS 238

Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSST---DDFKV-----------DTFEYRLLRE 233
             + GT+  T  + +  +   Y  G     T    D ++           D  E  +L+ 
Sbjct: 239 PPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKI 298

Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSG 291
           +  ++S    Y   +   +       L  V  P +  K R  + +++E   A F  ++  
Sbjct: 299 LFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVP- 357

Query: 292 NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            P     WFK   RL  S K+ I        L VRN    D   Y  + E P G
Sbjct: 358 QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVY--ICETPEG 409



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            R    + V+  P  +T+   P    E QS    C   P P     V+WY +   L    +
Sbjct: 2457 RSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKA---VQWYKDDTPLSPSEK 2513

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++ S +   A L IL +   D+G Y C+A    G A SS  + V+++E
Sbjct: 2514 FKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVEARE 2557



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDF 2697
            Q+ P+F+ H     +   G  + LE  V  + D  ++  W K+GV LT G          
Sbjct: 4895 QEGPMFS-HTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD 4951

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  +L I  L   D+G YTC+ +N  G+   +A + +
Sbjct: 4952 GTCSLLIAGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFV 3887
            PP F  ++   T E  E V+  CRV     PK  I WY++GK +     +  + D  G  
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 6070

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +L +  +   DSG+Y+C A +  G   T   I  +  P  +
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFV 6111



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP FE+   +     G   K   ++ G P PV+SW  K    V+ + + +   +  G  +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISW-YKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 131  LLIKQIGPGDEGEYTCTARNQYG 153
            L++  +   D G+Y C A +  G
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAG 6094



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EG++  F C +E +  P  +I W+ +   L +G ++++  +     + L I    +ED G
Sbjct: 6121 EGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2845 IYTCKATNSKGSATTSGSLR 2864
            +Y C+  N  GSA  S  LR
Sbjct: 6179 LYECELVNRLGSARASAELR 6198



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/67 (34%), Positives = 34/67 (50%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            +P  +V W  + + + AG+RFR   D     L I      DSG+Y+CRA N  GEA    
Sbjct: 36   NPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAV 95

Query: 3509 SMKVQGK 3515
             ++V  +
Sbjct: 96   GLQVDAE 102



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 4/124 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYV 2035
            P+F   +  +   EG       T+     P +R  WY +G  +  G++F+T  +   G +
Sbjct: 6108 PRFVNKVLASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLL 6165

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L I  A  ED G Y C+  N +G A  ++ +++ +      +    ++L    E+ + E
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQE 6225

Query: 2096 RPKP 2099
               P
Sbjct: 6226 TKVP 6229



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG+ A +   +     P +R  WY +G  L  G++F+T  +   G + L I +    D G
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 2580 LYMCKAINRAG 2590
            LY C+ +NR G
Sbjct: 6179 LYECELVNRLG 6189



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 145/671 (21%), Positives = 247/671 (36%), Gaps = 71/671 (10%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            +S    V  +PL  P    E +++ L C   P       V+W+ +   ++   +FK   +
Sbjct: 2464 VSDIPVVLTRPLE-PKTGRELQSVVLSCDFRPA---PKAVQWYKDDTPLSPSEKFKMSLE 2519

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT-DTQNEQAIEQ--I 1288
                 L I+    AD G Y  +A    GSAH+S  V V  R   VT   Q+ +A E+   
Sbjct: 2520 GQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWA 2575

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
                + +   ++V   +  M  P ++ + H I      +  +   +Q      +R     
Sbjct: 2576 SFSCELSHEDEEVEWSLNGM--PLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLK 2633

Query: 1349 NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN------------QLGEAVT 1396
                 +   R +P       ALD LS     +    C+ ++            QLG +  
Sbjct: 2634 VSTSARLEVRVKPVVFLK--ALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDK 2691

Query: 1397 SCALRVIAKKDLILESQHP--SGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIE 1454
               L     + L++    P  +GL       + +R  +  + D  V I  R     K++E
Sbjct: 2692 YDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETR-ARVRVHDLHVGITKRL----KTME 2746

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
             V+EG+   FEC L   + S+    W   G+ V    RF+         L + +    D+
Sbjct: 2747 -VLEGESCSFECVLSHESASD-PAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDA 2804

Query: 1515 G--IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDE 1572
            G  +++ R +    T + S  L  R     +     +  +   + +E R +  R      
Sbjct: 2805 GEVVFSVRGL----TSKAS--LIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVH 2858

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
                      S K   + EG  A    R   + DA    E+    +  KS +        
Sbjct: 2859 WLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAG---EYTCEVEASKSTASLHVEEKA 2915

Query: 1633 GFVALDIMSCLPEDSGT--YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRL-- 1688
                 ++ +   E+ GT  +TC+  +     VT    ++  + S   +   EG   RL  
Sbjct: 2916 NCFTEELTNLQVEEKGTAVFTCKTEHP-AATVTWRKGLLELRASGKHQPSQEGLTLRLTI 2974

Query: 1689 NQLE--DTSKYQRHSAQDEVITQAPV------FTMPMKDIRVAENQAAHFEARLIPVG-D 1739
            + LE  D+  Y     Q +   Q  V          ++D+ V E  +A F  R+ P   +
Sbjct: 2975 SALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYE 3034

Query: 1740 PKLRVEWLRNGVPIEASNRLTTM--HDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            P   V W  +  P+ A N L  +     GY  L ++ +  +DSGT       E G+   S
Sbjct: 3035 P---VHWFLDKTPLHA-NELNEIDAQPGGYHVLTLRQLALKDSGT----IYFEAGDQRAS 3086

Query: 1798 STLFVQSKASL 1808
            + L V  K S+
Sbjct: 3087 AALRVTEKPSV 3097



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 56/243 (23%), Positives = 94/243 (38%), Gaps = 23/243 (9%)

Query: 99   PTP-VVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
            P P  V W +   PL    K+ M    Q  ++ +L  ++ P D G Y C A    G A  
Sbjct: 2494 PAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRIL--RLMPADAGVYRCQA----GSAHS 2547

Query: 158  SVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSS 217
            S  +  E                  +E  E    G   ++ E S + ++V ++       
Sbjct: 2548 STEVTVEAREVTVTGPLQD------AEATEE---GWASFSCELSHEDEEVEWSLNGMPLY 2598

Query: 218  TDDFKVDTFEYRLLREVSFRESITKRYVG---ESDVQISTEIDRSLGPVSPPKIAQKPRN 274
             D F   + + R  R     +SI +   G    S +++ST     +  V P    +   +
Sbjct: 2599 NDSFHEISHKGR--RHTLVLKSIQRADAGIVRASSLKVSTSARLEVR-VKPVVFLKALDD 2655

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
               +E      Q ++S +P   V W K+G +L  S+K++ + T     L V +    D+G
Sbjct: 2656 LSAEERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAG 2714

Query: 335  HYT 337
             YT
Sbjct: 2715 LYT 2717



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 9/156 (5%)

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            EV W   + Q R     + +V E    +L +  +   D+G   C +R+    T+ Q  ++
Sbjct: 1838 EVVWRCGNTQPRVGKRFQ-MVAEGPVRSLTVLGLRAEDAGEYVCESRDD--HTSAQLTVS 1894

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            V    +VV  KF+   ST+   EG         V      + W +DG  + P+ +  I  
Sbjct: 1895 V---PRVV--KFMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQ 1948

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
             G + +L I      DA      A+  + S A R R
Sbjct: 1949 SGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 82/367 (22%), Positives = 142/367 (38%), Gaps = 35/367 (9%)

Query: 1471 VTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEV 1530
            V+D    V W K+G  +    ++  +H  G   L + D+  ED+G+YTC     VG++E 
Sbjct: 2670 VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEET 2725

Query: 1531 SCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNV--- 1587
              R+        V  T+    L+ ++VLE  S      +  E  +   + T   K V   
Sbjct: 2726 RARVRVHDLH--VGITKR---LKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSS 2780

Query: 1588 ----EIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
                  ++G++     R    SDA  +V +       K+     E        L+     
Sbjct: 2781 SRFQATRQGRKYILVVREAAPSDAG-EVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVA 2839

Query: 1644 PEDSGTYTCRAINALGEAV---TSGIAIVHSKK-SIYLESQHEGALPRLNQLEDTSKY-- 1697
            P +     C    A G  V       AI  S+K  +  E      + R   L+D  +Y  
Sbjct: 2840 PGEDVELRCELSRA-GTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTC 2898

Query: 1698 ----QRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753
                 + +A   V  +A  FT  + +++V E   A F  +      P   V W +  + +
Sbjct: 2899 EVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCK---TEHPAATVTWRKGLLEL 2955

Query: 1754 EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ 1813
             AS +     +   + L +  +   DS TYTC    ++G+A + + L VQ +    +E  
Sbjct: 2956 RASGKHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLVQGRRVHIIEDL 3011

Query: 1814 HESALQK 1820
             +  +Q+
Sbjct: 3012 EDVDVQE 3018



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 45/197 (22%), Positives = 79/197 (40%), Gaps = 15/197 (7%)

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            +++ +A     ++  QD  ++EG+   F CR++     E  W +    ++ +  + I V 
Sbjct: 4242 QLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVE 4301

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            +   H L +  VTL D+G V+       G  + + +L V  K  VV  + +E    L   
Sbjct: 4302 QGTLHLLTLHKVTLEDAGTVSF----HVGTCSSEAQLKVTAKNTVV--RGLENVEAL--- 4352

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            EG   +   +         TW  D  P+    N E+    +G    L +   +  D+   
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVRTSENAEVVFFENGLRHLLLLKNLRPQDS--- 4409

Query: 562  QCTAQNVAGSTATRARL 578
             C    +AG   T A L
Sbjct: 4410 -CRVTFLAGDMVTSAFL 4425



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 5/114 (4%)

Query: 941  LRVEWLKDGRPV-EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            +R  WLKDG  + +           G  +L I  +   DAG YTC+  N  GQ T SA  
Sbjct: 4927 VRARWLKDGVELTDGRHHHIDQLGDGTCSLLIAGLDRADAGCYTCQVSNKFGQVTHSA-C 4985

Query: 1000 TIVTKKDIIAESQHPGGLEKIQYLEDASRYSK--RTEEEVKITQKPRFLGPLKG 1051
             +V+  +  AES   G L+   +   A R  +  RT+   +++ +  FL   +G
Sbjct: 4986 VVVSGSESEAESSSGGELDD-AFRRAARRLHRLFRTKSPAEVSDEELFLSADEG 5038



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 9/129 (6%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAG 980
            EG  A F   +E  G    ++ W KDG  +   ++  T      G + L I++ +  D G
Sbjct: 6121 EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 6178

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGL-EKIQYLEDASRYSKRT---EEE 1036
             Y C   N +G A  SA L I +      E  H   L   ++  E  ++  K+T   EE 
Sbjct: 6179 LYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEET 6238

Query: 1037 V-KITQKPR 1044
            +  + + PR
Sbjct: 6239 ITTVVKSPR 6247



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            ++ EG  AH    L   G     +EW      +    + + V       L + G +  D+
Sbjct: 3989 EVDEGGTAHLCCELSRAGAS---VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA 4045

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            G Y+C   +    A +SV++         +P+F T +Q++E  + G  A   C +   + 
Sbjct: 4046 GDYTCDTGHTQSMASLSVRV--------PRPKFKTRLQSLE-QETGDIARLCCQLSDAES 4096

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
              + ++W   G  +    + +  S      L I   +  D+GEY C
Sbjct: 4097 GAV-VQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC 4141



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-ILI 4469
            P+F  ++Q   V +     F+    G+P+P ++W+++   ++    + I+        LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I  V   D  V+  +AEN  G +   A L V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 6/132 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++     V   G +    C +  +  PT ++ W  + +P+ +G R++   D     L I
Sbjct: 12   FLTRPKAFVVSVGKDATLSCQIVGN--PTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTI 69

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQH----PQGKAGLEAVEQAE 2891
                  DSG Y C+A N+ G A  +  L+   +        H    P      E  E   
Sbjct: 70   LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATF 129

Query: 2892 EARLAKGRRPSV 2903
              R+    RP+V
Sbjct: 130  RCRVGGSPRPAV 141



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R         L +      D+G YSC+A    G   +S  L   
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVA 1620

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            +           H + ++  + G SA   C V        ++ WY +G+ +  S++++  
Sbjct: 1621 EPKVVFAKEQPAH-REVQA-EAGASATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRVE 1675

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            +      L +      D+GEY C A
Sbjct: 1676 AVGCTRRLVVQQAGQADAGEYSCEA 1700



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 13/122 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P KF   +++    E       C +  K  P   +EW++  + L  G R+    D     
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELS-KMAP---VEWWKGHETLRDGDRHSLRQDGARCE 3680

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  + AED+GEY+C      G++ T A ++ + +P   ++     G++  EA     A
Sbjct: 3681 LQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE-----GLRNEEATEGDTA 3731

Query: 3949 TI 3950
            T+
Sbjct: 3732 TL 3733



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 11/119 (9%)

Query: 1300 QVREDITV-MQAPQ--FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            Q R   T+ ++APQ  F   L +++  EG+   L+C L    + T  V W   G  ++  
Sbjct: 3876 QERTSATLTVRAPQPVFREPLQSLQAEEGSTATLQCELS---EPTATVVWSKGGLQLQAN 3932

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL-ESQH 1414
             R  P  +     L L  +  ED+G YTC      G   TS  L V A     L E QH
Sbjct: 3933 GRREPRLQGCTAELVLQDLQREDTGEYTCTC----GSQATSATLTVTAAPVRFLRELQH 3987



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTL 4571
            P F+ T  +     G  +RL+  V     +   WLK+G ++  D R+  +++  DGT +L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT-DGRHHHIDQLGDGTCSL 4956

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            LI      D+G Y C   N  G+    A  VVS
Sbjct: 4957 LIAGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGF 3752
            PP F  E+ D      G  V   CRV   G P   I W+ +G+          + D  G 
Sbjct: 6013 PPDFEEELAD-CTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGS 6069

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             AL +D +   D+G+Y C A +  G+ +T  KI
Sbjct: 6070 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKI 6102



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 37/162 (22%), Positives = 66/162 (40%), Gaps = 10/162 (6%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
            G      C V  +   EVTW+ + +++    + K+ +  +G    L++     +D+G  +
Sbjct: 905  GASATLSCEVA-QAQTEVTWYKDGKKLSS--SSKVCMEATGCTRRLVVQQAGQADAGEYS 961

Query: 465  CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            C A    G       L+V E + V A   V   S +    G    L+   V      + W
Sbjct: 962  CEA----GGQRLSFHLDVKEPKVVFAKDQVAH-SEVQAEAGANATLSCE-VAQAQAEVMW 1015

Query: 525  QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
             KDG  +  + ++ +   G    L + +A  +DA  Y C A+
Sbjct: 1016 YKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEAR 1057



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++R   A  M  L +      D+G Y+C A    G   +S  L+ V
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRLSFHLD-V 1343

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             + K    +     + ++  + G  A   C V        ++ WY +G+ +  S++++  
Sbjct: 1344 SEPKAVFAKEQLAHRKVQA-EAGAIATLSCEVA---QAQTEVTWYKDGKKLSSSSKVRME 1399

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
            +      L +      D+GEY C A
Sbjct: 1400 AVGCTRRLVVQQACQADTGEYSCEA 1424



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165
            +AR   V   L DA   EEG WA F C ++ H    V W LNG  + N S +++++ G  
Sbjct: 2554 EAREVTVTGPLQDAEATEEG-WASFSCELS-HEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611

Query: 4166 HFDIPKTRQ 4174
            H  + K+ Q
Sbjct: 2612 HTLVLKSIQ 2620



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
           ES +++       L    PP  A +   ++L E  +AQ   +LS +    VTW K+G+ L
Sbjct: 690 ESSIRMEVRAAPGLTANKPPAAAAREVLARLHE--EAQLLAELS-DQAAAVTWLKDGRTL 746

Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               K+E+  +     L VR+  + D+G Y
Sbjct: 747 SPGPKYEVQASAGRRVLLVRDVARDDAGLY 776



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 11/175 (6%)

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            F K  + + V E      +  +T RP+PE+ W  N   +    N +I   E   H L++ 
Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHA-EGARHRLVLH 2047

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            NV  +D G   C    ++ +   Q +L V E  QV   + V     +  RE     +  +
Sbjct: 2048 NVGFADRGFFGC----ETPDDKTQAKLTV-EMRQV---RLVRGLQAVEAREQGTATMEVQ 2099

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
                     +W +DG+     P   +   G   TL +   +  D+      A+ V
Sbjct: 2100 LSHADVDG-SWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGV 2153



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371
            +F  AL ++E +EG    L C L  V      V+W      ++ G ++    E   + L 
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELV 3242

Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            + ++ P+DSG Y+C      G+  TS  L V A
Sbjct: 3243 VRNLRPQDSGRYSC----SFGDQTTSATLTVTA 3271



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
            +P F  PLQ L + +EG  A  + +L   S+PT  V W K G  + A+ R          
Sbjct: 3889 QPVFREPLQSL-QAEEGSTATLQCEL---SEPTATVVWSKGGLQLQANGRREPRLQGCTA 3944

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
             L +  L+ ED G YT    ++   A  T +
Sbjct: 3945 ELVLQDLQREDTGEYTCTCGSQATSATLTVT 3975



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            Q  +A+ K   +++    Q+R  + + V + P F  +L   T    G++    CR+   P
Sbjct: 5985 QARTAIIKSSWVKEICGIQQR--LALPVWRPPDFEEELADCTA-ELGETVKLACRVTGTP 6041

Query: 1873 DPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             P   + WY +GK +Q   H     +  G  AL + ++ G DSG+Y C A +  G   + 
Sbjct: 6042 KPV--ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTL 6099

Query: 1932 IRLNVQ 1937
             ++ VQ
Sbjct: 6100 GKILVQ 6105



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 11/151 (7%)

Query: 4585 ECVAINSA-GEA-RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL----KDKIVAEGQ 4638
            ECV    A GE  R     V  + A +    PQT     PP+ + P     + + VA G+
Sbjct: 4580 ECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGE 4639

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC-VA 4697
             +    ++V +    + W+KG + I+P   F++     +  L I     ED+G+Y C +A
Sbjct: 4640 DVSLELEVVAEAGEVI-WHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLA 4698

Query: 4698 YNS--AGRVTVAAKLKVTQPDQADNLPALTP 4726
              S      T    L     D+A   P+L P
Sbjct: 4699 QGSICPAAATFQVALSPASVDEAPQ-PSLPP 4728



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/151 (23%), Positives = 51/151 (33%), Gaps = 4/151 (2%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            V PE +     +   PVF++      V++G    F C VTG P P V W  +G  +    
Sbjct: 5111 VPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD 5170

Query: 4156 RYKLTYD--GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNA 4213
             Y +  D  G +   I      D G    +             L+V     DY       
Sbjct: 5171 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADAT 5230

Query: 4214 PRPWYDETTQY--QRTETELEKTFEERQVLQ 4242
                Y     Y   R +   E T +E Q+ Q
Sbjct: 5231 ESSSYFSAQGYLSSREQEGTESTTDEGQLPQ 5261



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP FV+   A    EGE A+F C + G P P++ W  +G  +  G++++
Sbjct: 6107 PPRFVNKVLASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            PRF+T+ ++    V  + T   CQ+  VG+P  +V W  + +P+    RF    D     
Sbjct: 10   PRFLTRPKAFVVSVGKDAT-LSCQI--VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYR 66

Query: 4033 MNFGWVYPEDSGEYLCRATNLYG 4055
            +    +   DSG+Y+CRA N  G
Sbjct: 67   LTILDLALGDSGQYVCRARNAIG 89



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 12/111 (10%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            ++W+ +   +  S + +      M  L IL     D+G Y C+A +     E++V     
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTV----- 2553

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++   T  +Q+ E  ++G  A F C    +   D ++EW  NG P+
Sbjct: 2554 ---EAREVTVTGPLQDAEATEEGW-ASFSC---ELSHEDEEVEWSLNGMPL 2597



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 7/97 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P   I PL+      G  +     +   G P   + WLK+ ++I  S ++  +       
Sbjct: 2826 PAAIIKPLEDQWVAPGEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAM 2882

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            L +   +++D+GEYTC   +    +++ A LHV  +A
Sbjct: 2883 LVIRGASLKDAGEYTCEVEA----SKSTASLHVEEKA 2915



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 43/172 (25%), Positives = 64/172 (37%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +T+    R           L+I G    D+G YSC      GQ   S  L   
Sbjct: 3743 VEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVC----GQERTSATLTV- 3797

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
               +    RF   ++N E  ++G +A  +C +         +EW    + +R   R    
Sbjct: 3798 ---RALPARFIEDVKNQEA-REGATAVLQCEL----SKAAPVEWRKGSETLRGGDRYSLR 3849

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             D     L I      D+GEY C      G++ T AT+       V+ E LQ
Sbjct: 3850 QDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVRAPQPVFREPLQ 3897



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 17/143 (11%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S ++ V  P+++    + E      + EG+ A F+C++        R      G  LQ+ 
Sbjct: 4240 SAQLTVRAPEVT----ILEPLQDVQLSEGQDASFQCRLSRASGQEARWAL--GGVPLQAN 4293

Query: 2289 ARFHITFDFGYVSLDIQHCVP-EDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
                IT + G + L   H V  EDAG  S      +G C+S   + VTAK +++      
Sbjct: 4294 EMNDITVEQGTLHLLTLHKVTLEDAGTVSFH----VGTCSSEAQLKVTAKNTVV------ 4343

Query: 2348 EGLEKIRELESAEPFKRPEIPEP 2370
             GLE +  LE  E     ++ +P
Sbjct: 4344 RGLENVEALEGGEALFECQLSQP 4366



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 21/82 (25%), Positives = 34/82 (41%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F     D +   G   R +C V  +      W  +  ++ D  +H I     G  +L+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957

Query: 452  ITNVTLSDSGVVTCVARNKSGE 473
            I  +  +D+G  TC   NK G+
Sbjct: 4958 IAGLDRADAGCYTCQVSNKFGQ 4979



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 39/154 (25%), Positives = 61/154 (39%), Gaps = 11/154 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            + W+ +GK + +S ++R V A G    L +      D+G YSC A    G   +S +L  
Sbjct: 1657 VTWYKDGKKLSSSSKVR-VEAVGCTRRLVVQQAGQADAGEYSCEA----GGQRLSFRLHV 1711

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
             +     +P+ +      E L   +      T          + W  +G  +R S R +T
Sbjct: 1712 AEL----EPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHET 1767

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
             S      L +   Q  DS  Y CR     G+DF
Sbjct: 1768 ASQGDTHTLTVHGAQVLDSAIYSCRV-GAEGQDF 1800



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            A +F R L  +    G  V L C L P       V W C     + G RF+   E    +
Sbjct: 1808 AAKFCRLLEPVCGELGGTVTLACELSPA---CAEVVWRCGNTQPRVGKRFQMVAEGPVRS 1864

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            L +L +  ED+G Y C++ +    A  + ++  + K
Sbjct: 1865 LTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVK 1900



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+S L+ +V +EG    F+C V PS    + + WF +   L    ++  +   +  SL I
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPS---DVAVVWFRDGALLQPSEKFAISQSGASHSLTI 1957

Query: 2836 THTYEEDSGIYTCKATNSKGSA 2857
            +    ED+G  T +A  +  SA
Sbjct: 1958 SDLVLEDAGQITVEAEGASSSA 1979



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 57/275 (20%), Positives = 105/275 (38%), Gaps = 35/275 (12%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V     + V W ++G  +QP  +  I +   +++L I +   +D+G+   + + + G + 
Sbjct: 1921 VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ---ITVEAEGASS 1977

Query: 4597 CDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
              A  V   P   K K +PQT                 V E  ++    ++  +P P ++
Sbjct: 1978 SAALRVREAPVLFKKKLEPQT-----------------VEERSSVTLEVELT-RPWPELR 2019

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            W +    + P K  ++      + L +      D G + C   +   +    AKL V   
Sbjct: 2020 WTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ----AKLTV--- 2072

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
             +   +  +  L+ +   E   A  + Q+ S       W R+G    + P   +   G  
Sbjct: 2073 -EMRQVRLVRGLQAVEAREQGTATMEVQL-SHADVDGSWTRDGLRFQQGPTCHLAVRGPM 2130

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              L +     ED+G    +A      V TSA+LVV
Sbjct: 2131 HTLTLSGLRPEDSGLMVFKAE----GVHTSARLVV 2161



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 5/70 (7%)

Query: 804  VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            V+WYKD  P++ S +           L I+ L   DAG Y  +A    G A S+  + V 
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 864  ARS-TVTADL 872
            AR  TVT  L
Sbjct: 2555 AREVTVTGPL 2564



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 32/126 (25%), Positives = 56/126 (44%), Gaps = 11/126 (8%)

Query: 2617 EQIQLKEAAMNKVPEMFVDTG----VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            + IQ  +A + +   + V T     V+  P+    LK+ D L   +   L  Q E  +DP
Sbjct: 2617 KSIQRADAGIVRASSLKVSTSARLEVRVKPV--VFLKALDDLSAEERGTLALQCEV-SDP 2673

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
               + W K+GV L    +       G   L ++ +  +D+G+YTC     +G   + A +
Sbjct: 2674 EAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARV 2729

Query: 2733 KIEDRH 2738
            ++ D H
Sbjct: 2730 RVHDLH 2735



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 11/126 (8%)

Query: 1815 ESALQKIQQLEDSSRY-----QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRI 1868
            E  LQ +Q+ ED+  Y      +     + V  AP RF+ +L    ++ EG +AH  C +
Sbjct: 3945 ELVLQDLQR-EDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQ-EVDEGGTAHLCCEL 4002

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
                     VEW      L    +Y+   D   A L +  V  ED+G+YTC   +    A
Sbjct: 4003 SR---AGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMA 4059

Query: 1929 VSSIRL 1934
              S+R+
Sbjct: 4060 SLSVRV 4065



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 35/166 (21%), Positives = 63/166 (37%), Gaps = 10/166 (6%)

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            +Y   T  ++T   + ++E  +    V+   D +VT  +   F C V+      V W + 
Sbjct: 4138 EYACVTGGQKTAASLRVTEPEVT--IVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQ 4195

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
               ++ +   ++ V +   H L +  VT  D+G V+       G  A   +L V   E  
Sbjct: 4196 GLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF----HLGNHASSAQLTVRAPEVT 4251

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534
            +    +E    + + EG+      R          W   GVP+  N
Sbjct: 4252 I----LEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQAN 4293



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 4/106 (3%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG-HRYRT 1895
            E+   + P F +   G T+   G +   EC +    D  +R  W  +G  L  G H +  
Sbjct: 4891 EMKQQEGPMF-SHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHID 4947

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
                G  +L I  +   D+G YTC+  N  GQ   S  + V   ES
Sbjct: 4948 QLGDGTCSLLIAGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSES 4993



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   ++  +   + G   +   +++G P+P ++W+K+G+ +     H +I   + +   
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 325  VRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESP 358
            + ++    DSG Y   A +  G   T G + V+ P
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 16/201 (7%)

Query: 2538 PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXX 2597
            P++   W  +GVEL+ G            +L I      D G+Y+C A +          
Sbjct: 2192 PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHD---AQSSASV 2248

Query: 2598 XXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEG 2657
                    +I + +  E   +IQ    A N   E      V++ P+ T      DK+   
Sbjct: 2249 KVQGRTYTLIYRRVLAEDAGEIQF--VAEN--AESRAQLRVKELPV-TLVRPLRDKIAME 2303

Query: 2658 QH-VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            +H   LE QV   +  + ++ WFK    L  G + +   D     L I+ +  +D   YT
Sbjct: 2304 KHRGVLECQV---SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYT 2360

Query: 2717 CKATNLLGEAVSTASIKIEDR 2737
            C A    G+  ++A   +E++
Sbjct: 2361 CDA----GDVKTSAQFFVEEQ 2377



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 8/96 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P RF   +KD ++V EGG     C +  V  P   + W +       G +     +   +
Sbjct: 3184 PVRFQEALKD-LEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAML 3239

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
             L +  +  +D+G Y+C     +G  TT+A +T +A
Sbjct: 3240 ELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTA 3271



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 7/87 (8%)

Query: 1583 SLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            +LK++E+ EG  A    R + +S     V+W + N  L+ G +++       + L + + 
Sbjct: 3190 ALKDLEVLEGGAATL--RCV-LSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNL 3246

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIV 1669
             P+DSG Y+C    + G+  TS    V
Sbjct: 3247 RPQDSGRYSC----SFGDQTTSATLTV 3269



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 6/109 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P K  +  RN +  EGA A  + +LS      V W+K  + L + ++H +        L+
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELS--KMAPVEWWKGHETLRDGDRHSLRQDGARCELQ 3682

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            +R     D+G Y  +     G   TS  L V +    +++  R++  T+
Sbjct: 3683 IRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLRNEEATE 3727



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 9/124 (7%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P KFI  +++    E +     C +  K  P   +EW +  + L  G R+    D     
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS-KAAP---VEWRKGHETLRDGDRHSLRQDGSRCE 3768

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L I  +   D+GEY C      G++ T AT++ + LP   +++ V     R  A   ++ 
Sbjct: 3769 LQIRGLAVVDAGEYSCVC----GQERTSATLTVRALPARFIED-VKNQEAREGATAVLQC 3823

Query: 3949 TIKK 3952
             + K
Sbjct: 3824 ELSK 3827



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 7/121 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L N    EGD     C +  +      +EW   ++ L  G R+    D S   L I
Sbjct: 3716 FIEGLRNEEATEGDTATLWCELSKAAP----VEWRKGHETLRDGDRHSLRQDGSRCELQI 3771

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                  D+G Y+C     + SAT   ++R    + I  D ++ + + G  AV Q E ++ 
Sbjct: 3772 RGLAVVDAGEYSCVCGQERTSATL--TVRALPARFIE-DVKNQEAREGATAVLQCELSKA 3828

Query: 2896 A 2896
            A
Sbjct: 3829 A 3829



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 10/116 (8%)

Query: 1831 QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Q R    + V   P RFI  +    +  EG +A  +C +         VEW    + L+ 
Sbjct: 3788 QERTSATLTVRALPARFIEDVKNQ-EAREGATAVLQCELSKAAP----VEWRKGSETLRG 3842

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
            G RY    D     L I  +   D+GEY+C      GQ  +S  L V++ + + R+
Sbjct: 3843 GDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVRAPQPVFRE 3894



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 76/330 (23%), Positives = 129/330 (39%), Gaps = 41/330 (12%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P  F+  +   + EE   +  +C V    DP+  + W ++G  L    +Y  ++  G   
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCEVS---DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG 2702

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
            L +  V  ED+G Y C      G + T+A +   ++ D  L   + + +K  E L     
Sbjct: 2703 LVVHDVSPEDAGLYTCHV----GSEETRARV---RVHD--LHVGITKRLKTMEVLEGESC 2753

Query: 3949 TIKKYTSEVYLTEDDLYDVDKK---QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNM 4005
            + +   S    ++  ++ V  K      RF    Q +  ++ +     E   +  G+   
Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVR----EAAPSDAGEVVF 2809

Query: 4006 KVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCR----ATNLYGMDETKA 4061
             V    +   L+ + R   I       +   WV P +  E  C      T ++ + + KA
Sbjct: 2810 SVRGLTSKASLIVRERPAAIIK----PLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKA 2865

Query: 4062 VIKTTGKPGIVYDSQLP------KHMKSI-EKIREMEASWQVTPEQVVEESKARCPPVFV 4114
            + K+  K  +V +  +         +K   E   E+EAS + T    VEE KA C   F 
Sbjct: 2866 IRKSQ-KYDVVCEGTMAMLVIRGASLKDAGEYTCEVEAS-KSTASLHVEE-KANC---FT 2919

Query: 4115 SLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
                 + VEE   A F C+ T HP   V W
Sbjct: 2920 EELTNLQVEEKGTAVFTCK-TEHPAATVTW 2948



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            I + P +FI  +K+    E      +C +         +EW +  + L  G RY    D 
Sbjct: 3533 IRALPARFIEDVKNQEAREGATAVLQCELNSAAP----VEWRKGSETLRDGDRYSLRQDG 3588

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+GEY C      G++ T A ++ + LP
Sbjct: 3589 TKCELQIRGLAMADTGEYSCVC----GQERTSAMLTVRALP 3625



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 9/124 (7%)

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            Q R    + V   P   T+     + +EG +A   C +         VEW+   + L+ G
Sbjct: 3612 QERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDG 3667

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES-IIRDSQHE 1949
             R+    D     L I  +  ED+GEY C      G+  +S  L V++  S  I   ++E
Sbjct: 3668 DRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLRNE 3723

Query: 1950 SALE 1953
             A E
Sbjct: 3724 EATE 3727



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 9/101 (8%)

Query: 1454 ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAED 1513
            E   EG      C+L  +      VEW+K  + +  G R     D     L I  L+AED
Sbjct: 3635 EEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAED 3690

Query: 1514 SGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLE 1553
            +G Y C    + G +  S  LT R+  +  +   +NE   E
Sbjct: 3691 AGEYLC----MCGKERTSAMLTVRAMPSKFIEGLRNEEATE 3727



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 9/145 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +GK + +S ++          L +     TD+G YSC A    GQ  +S +L   
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEAR---GQ-RVSFRLHIT 1068

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            +         + H  N    + G SA   C V        ++ WY +G+ +  S+++   
Sbjct: 1069 EPKMMFAKEQSVH--NEVQAEAGASAMLSCEVA---QAQTEVTWYKDGKKLSSSSKVGME 1123

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
                   L +      D+GEY C A
Sbjct: 1124 VKGCTRRLVLPQAGKADAGEYSCEA 1148



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P  F++  K+    +GG A     L     PV  W      L   +KYS+R  ++   + 
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGDKYSLR--QEGAMLE 3240

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163
            L+++ + P D G Y+C+  +Q   A  +V   P
Sbjct: 3241 LVVRNLRPQDSGRYSCSFGDQTTSATLTVTALP 3273



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 8/97 (8%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P  FI +++     E       C +  K  P   +EW +  + L  G R+    D     
Sbjct: 3361 PAHFIGRLRHQESIEGATATLRCELS-KAAP---VEWRKGRESLRDGDRHSLRQDGAVCE 3416

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L I  +   D+GEY C      GE+ T AT++ K LP
Sbjct: 3417 LQICGLAVADAGEYSCVC----GEERTSATLTVKALP 3449



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 38/172 (22%), Positives = 67/172 (38%), Gaps = 17/172 (9%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW    +T+    R           L+I G    D+G YSC    +   A ++V+   +
Sbjct: 3567 VEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPI 3626

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                    +FT  ++N E   +G +A   C +  +      +EW+   + +R   R    
Sbjct: 3627 --------KFTEGLRNEEAT-EGATAVLRCELSKM----APVEWWKGHETLRDGDRHSLR 3673

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             D     L I      D+GEY+C      G++ T A +        ++E L+
Sbjct: 3674 QDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGLR 3721



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 9/108 (8%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV   P +F+  L N E  EG    L C L  +      VEW+   + ++ G R     
Sbjct: 3619 LTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQ 3674

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILE 1411
            +     L +  +  ED+G Y C      G+  TS  L V A     +E
Sbjct: 3675 DGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE 3718



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 8/94 (8%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P +FI  +K+    E      +C +  K  P   +EW +  + L  G RY    D     
Sbjct: 3801 PARFIEDVKNQEAREGATAVLQCELS-KAAP---VEWRKGSETLRGGDRYSLRQDGTRCE 3856

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            L I  +   D+GEY C      G++ T AT++ +
Sbjct: 3857 LQIHGLSVADTGEYSCVC----GQERTSATLTVR 3886



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 60/272 (22%), Positives = 105/272 (38%), Gaps = 29/272 (10%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F +  ++ +  +G  A  + +L   PT  V W++    L    +   R    T +  L
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAE--L 3946

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            +++ +   D GEYTCT  +Q   A  +V   P               ++ V E       
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLTVTAAP-------VRFLRELQHQEVDEG------ 3993

Query: 192  GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE--SD 249
            GT     E SR    V +  G    S   F     +Y+++++ +  E + +    E   D
Sbjct: 3994 GTAHLCCELSRAGASVEWRKG----SLQLF--PCAKYQMVQDGAAAELLVRGVEQEDAGD 4047

Query: 250  VQISTEIDRSLGPVS----PPKIAQKPRNSKLQEGADAQFQVQLS-GNPRPRVTWFKNGQ 304
                T   +S+  +S     PK   + ++ + + G  A+   QLS       V W K G 
Sbjct: 4048 YTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGV 4107

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
             L    K+E+ +      L +   +  D+G Y
Sbjct: 4108 ELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 6/108 (5%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G   T  TLT  A    P  F        + E  +AH  C L     S   VEW      
Sbjct: 3964 GSQATSATLTVTAA---PVRFLRELQHQEVDEGGTAHLCCELSRAGAS---VEWRKGSLQ 4017

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
            L   ++ + + D     L + GV Q DAG YTC   +    A++S ++
Sbjct: 4018 LFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP F       T E GE  +  CRVTG PKP + W  +G  +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAV 6054



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/56 (32%), Positives = 28/56 (50%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            VG+P+ +  W  +   +  G+RFR   D     L I  +   D+G Y+C+A N  G
Sbjct: 34   VGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIG 89



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 7/122 (5%)

Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
           VGE  V     +       +  ++A+  R  + + GA A    +++   +  VTW+K+G+
Sbjct: 872 VGEDSVDFRLRVSEPKVVFAKEQLAR--RKLQAEAGASATLSCEVA-QAQTEVTWYKDGK 928

Query: 305 RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           +L +S+K  +  T     L V+   ++D+G Y+  A    G    S +L V+ P   + +
Sbjct: 929 KLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA----GGQRLSFHLDVKEPKVVFAK 984

Query: 365 DQ 366
           DQ
Sbjct: 985 DQ 986



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 45/172 (26%), Positives = 72/172 (41%), Gaps = 13/172 (7%)

Query: 2245 VTELRGTTHVFEGKTAHFECQV--EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
            +T+   T  V EG++  FEC +  E   DP +   +   GK + S++RF  T       L
Sbjct: 2738 ITKRLKTMEVLEGESCSFECVLSHESASDPAM---WTVGGKTVGSSSRFQATRQGRKYIL 2794

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPF 2362
             ++   P DAGE  V ++  L   TS  S+ V  + + I +    + +    ++E     
Sbjct: 2795 VVREAAPSDAGEV-VFSVRGL---TSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCEL 2850

Query: 2363 KRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCR---LIPVGDPTLKVE 2411
             R   P    + R    +  Q  D + EG  A    R   L   G+ T +VE
Sbjct: 2851 SRAGTPVHWLKDRKAIRKS-QKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 8/110 (7%)

Query: 1974 VVEKPQ-FGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V EKP  F + + +A +TEG  + L    +  + P     W  +G+ ++   R + +++ 
Sbjct: 3091 VTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPMC---WTKDGKTLRGSARCQLSHEG 3147

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082
                L I  A  +D+G Y C+A    G A ++S V+V A+   + + L +
Sbjct: 3148 HRAQLLITGATLQDSGRYKCEA----GGACSSSIVRVHARPVRFQEALKD 3193



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 7/90 (7%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            F   +KD+ V E  AA     L  V  P   V+W      +   ++ +   +   + L +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVV 3243

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            + + P+DSG Y+C      G+  TS+TL V
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTV 3269



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + + P +FI ++++    E       C +  K  P   +EW +  + L  G RY    D 
Sbjct: 3269 VTALPAQFIGKLRNKEATEGATATLRCELS-KTAP---VEWRKGSETLRDGDRYCLRQDG 3324

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+ EY C      GE+ T A+++ + +P
Sbjct: 3325 AMCELQIRGLAMVDAAEYSCVC----GEERTSASLTIRPMP 3361



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS--NRLTTMHDFG 1766
            + P+F+    D       A   E  +    D  +R  WL++GV +     + +  + D G
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD-G 4952

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
              +L +  ++  D+G YTC+  N+ G+ VT S   V S +  + ES
Sbjct: 4953 TCSLLIAGLDRADAGCYTCQVSNKFGQ-VTHSACVVVSGSESEAES 4997



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 6/125 (4%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK-NGQRLI-----NSNKHEIITTH 318
            PP++ ++    K+++G+   F V++ G P P V W +   +R +     ++  + + ++ 
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429

Query: 319  NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378
               +L + +  +   G YT +A N  G  + S  L V    +   Q++  + +  T  + 
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQG 5489

Query: 379  TEERI 383
            T + I
Sbjct: 5490 TTQAI 5494



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 12/117 (10%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI- 694
            PP+ +         +G  I F  ++E  G P   + WL+  +  E    +      GY  
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVE--GRPVPTVHWLR--EEAERGVLWIGPDTPGYTV 5425

Query: 695  -------SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
                   SL +L +  Q  G YTC A +A G A   A LHV+    +E   +  E L
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEAL 5482



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/90 (25%), Positives = 40/90 (44%)

Query: 4724 LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNT 4783
            LT  +  VV  G+ A    QI     P + W ++   +     F++  +G+   L I + 
Sbjct: 13   LTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDL 72

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               D+G + CRA  A G+   +  L V ++
Sbjct: 73   ALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 9/103 (8%)

Query: 1425 EDTSRY---KKTDIIDESVTIK-PRFVTRPKSIENVI--EGQHVHFECKLEPVTDSNLKV 1478
            ED   Y    + D     +T+  PR V     +  V+  EG    F+C + P   S++ V
Sbjct: 1873 EDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP---SDVAV 1929

Query: 1479 EWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
             WF++G  +    +F         +L I DL+ ED+G  T  A
Sbjct: 1930 VWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEA 1972



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 49/215 (22%), Positives = 84/215 (39%), Gaps = 18/215 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P  F+  ++D +   E   V  +C +     P + + W  +G     G  +         
Sbjct: 2165 PVSFSRPLQDVVTT-EKEKVTLECELSR---PNVDVRWLKDGVELRAGKTMAIAAQGACR 2220

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEK--IKEL 3811
            +L I      D G Y C A +    A ++A +    +   ++  ++    +GE   + E 
Sbjct: 2221 SLTIYRCEFADQGVYVCDAHD----AQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAEN 2276

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
               R     KE P+    P    +I    +E+  GV  EC+V        ++ W++  + 
Sbjct: 2277 AESRAQLRVKELPVTLVRP-LRDKI---AMEKHRGV-LECQVSRAS---AQVRWFKGSQE 2328

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906
            L  G +Y  V D  +  L I  V+AED   Y C A
Sbjct: 2329 LQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PKF T+++S   E  +  R  C++   E   + ++W + G  L +G +Y          L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAV-VQWLKEGVELHAGPKYEMRSQGATREL 4126

Query: 3890 DILYVYAEDSGEYIC 3904
             I  + A+D+GEY C
Sbjct: 4127 LIHQLEAKDTGEYAC 4141



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            K  ++  E ++   P F+    D  +   G  +  +C V    D  +R  W  +G     
Sbjct: 4884 KGYKVRKEMKQQEGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVELTD 4940

Query: 3741 GSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            G   H   L D G  +L I  +   DAG YTC+ +NK+G  T +A +  S
Sbjct: 4941 GRHHHIDQLGD-GTCSLLIAGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFGYVA 2036
            P F + + +     G  V L   +T    P   + WY +G+ VQ   H        G  A
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCA 6071

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +      D+G YMC A +A G   T   + V
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 3/113 (2%)

Query: 1035 EEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT 1094
            ++ + +  PRFL   K     V G+ A    ++    + T  V W  + + +T+  R + 
Sbjct: 2    DQPQFSGAPRFLTRPKAFVVSV-GKDATLSCQIV--GNPTPQVSWEKDQQPVTAGARFRL 58

Query: 1095 YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIH 1147
              D     L I  +   DSG Y   ARNA GEA  +  + V+  ++    + H
Sbjct: 59   AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH 111



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 9/115 (7%)

Query: 1825 EDSSRY--QRREDVEVA--VNQAPRFITQLNGPTKL--SEGQSAHYECRIEPYPDPNMRV 1878
            ED+  Y  + R+D   A      PR +  ++G + +   EG  A ++C + P    ++ V
Sbjct: 1873 EDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP---SDVAV 1929

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             W+ +G +LQ   ++  S      +L I  +  ED+G+ T +A      A   +R
Sbjct: 1930 VWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 7/93 (7%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P  F+  L  ++A E G +  +     V DP   + W K+G  +  S ++  +   G   
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG 2702

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +  ++ +D+G YTC      G  ET+A + V
Sbjct: 2703 LVVHDVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 7/123 (5%)

Query: 1831 QRREDVEVAVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Q R    + +   P RFI  +    +  EG +A  +C +         VEW    + L+ 
Sbjct: 3524 QERTSATLTIRALPARFIEDVKNQ-EAREGATAVLQCELNSAAP----VEWRKGSETLRD 3578

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR-LNVQSKESIIRDSQH 1948
            G RY    D     L I  +   D+GEY+C        A+ ++R L ++  E +  +   
Sbjct: 3579 GDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEAT 3638

Query: 1949 ESA 1951
            E A
Sbjct: 3639 EGA 3641



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 1581 TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIM 1640
            T  L+N E  EG  A     L  ++     VEW+  ++ L+ G R +   +     L I 
Sbjct: 3629 TEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQIR 3684

Query: 1641 SCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE 1678
              + ED+G Y C      G+  TS +  V +  S ++E
Sbjct: 3685 GLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIE 3718



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            RP F T L SLE  + GD A   C++    +    + W   G ++ AG +Y         
Sbjct: 4067 RPKFKTRLQSLEQ-ETGDIARLCCQLSDA-ESGAVVQWLKEGVELHAGPKYEMRSQGATR 4124

Query: 2168 ALDILYTYAEDSGTYMC 2184
             L I    A+D+G Y C
Sbjct: 4125 ELLIHQLEAKDTGEYAC 4141



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 49/191 (25%), Positives = 77/191 (40%), Gaps = 21/191 (10%)

Query: 1678 ESQHEGALPRL--NQLE--DTSKY------QRHSAQDEVITQAPVFTMPMKDIRVAENQA 1727
            E + +GA   L  +QLE  DT +Y      Q+ +A   V          + D  V  ++ 
Sbjct: 4116 EMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADED 4175

Query: 1728 AHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT--TMHDFGYVALNMKYVNPEDSGTYTC 1785
              F   +   G     V+W   G+P++ SN +T   + D     L +K V PED+GT + 
Sbjct: 4176 VEFSCEVSRAG--ATGVQWCLQGLPLQ-SNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF 4232

Query: 1786 RAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEV--AVNQA 1843
                 LG   +S+ L V++     LE   +  L + Q      R  R    E   A+   
Sbjct: 4233 ----HLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGV 4288

Query: 1844 PRFITQLNGPT 1854
            P    ++N  T
Sbjct: 4289 PLQANEMNDIT 4299



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 6/112 (5%)

Query: 753  YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
            +  Y+ ++ +++Q  + P F     D  E Q G     E  +   +D  +R  W KDG  
Sbjct: 4883 FKGYKVRKEMKQQ--EGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVE 4937

Query: 813  IT-ASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            +T            G  SL I  L   DAG YT +  NK G+   +A + V+
Sbjct: 4938 LTDGRHHHIDQLGDGTCSLLIAGLDRADAGCYTCQVSNKFGQVTHSACVVVS 4989



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 10/137 (7%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYDFGY 2034
            E P F     + E   G  + LE  +    D  +R  W  +G  +  G H        G 
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGT 4953

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGE-------AVTTSSVKVDAKSGLYLDTLDEQRLKK 2087
             +L I      D G Y C+ +N  G+        V+ S  + ++ SG  LD    +  ++
Sbjct: 4954 CSLLIAGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARR 5013

Query: 2088 IQELEKYERPKPIEEEQ 2104
            +  L + + P  + +E+
Sbjct: 5014 LHRLFRTKSPAEVSDEE 5030



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 1/58 (1%)

Query: 928 HFEARL-EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTC 984
           H EA+L   + D    V WLKDGR +    +     + G   L ++ V   DAG Y C
Sbjct: 721 HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 9/130 (6%)

Query: 448  HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            H L ++ +   DSG++  V + +   T+   RL V E    +   F      +   E E 
Sbjct: 2131 HTLTLSGLRPEDSGLM--VFKAEGVHTS--ARLVVTE----LPVSFSRPLQDVVTTEKEK 2182

Query: 508  VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            V L    +  P   + W KDGV +     + I   G   +L I R + +D   Y C A +
Sbjct: 2183 VTLECE-LSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHD 2241

Query: 568  VAGSTATRAR 577
               S + + +
Sbjct: 2242 AQSSASVKVQ 2251



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 43/206 (20%), Positives = 79/206 (38%), Gaps = 14/206 (6%)

Query: 370  YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE-VTWFIN 428
            Y       ET  R+ + +  L     K  +  +V EG+   F+C ++     +   W + 
Sbjct: 2716 YTCHVGSEETRARVRVHD--LHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVG 2773

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
             + +      +    +   + L++     SD+G V    R  + + +    L V E+   
Sbjct: 2774 GKTVGSSSRFQA-TRQGRKYILVVREAAPSDAGEVVFSVRGLTSKAS----LIVRERPAA 2828

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            +     +++    V  GE V L        TP + W KD   I  + +  +  +G  + L
Sbjct: 2829 IIKPLEDQW----VAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAML 2883

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTAT 574
             I  A   DA  Y C  +  + STA+
Sbjct: 2884 VIRGASLKDAGEYTCEVE-ASKSTAS 2908



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 5/92 (5%)

Query: 2108 RPV-FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            RPV F  AL  LE L EG  A   C +  +  P   + W +    +R G +Y    +   
Sbjct: 3183 RPVRFQEALKDLEVL-EGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAM 3238

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            + L +     +DSG Y C   ++   A  T T
Sbjct: 3239 LELVVRNLRPQDSGRYSCSFGDQTTSATLTVT 3270



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 6/109 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P +  +  +N + +EGA A  Q +L  N    V W K  + L + +++ +        L+
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQ 3594

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            +R    +D+G Y+ +     G   TS  L V +    + +  R++  T+
Sbjct: 3595 IRGLAMADTGEYSCVC----GQERTSAMLTVRALPIKFTEGLRNEEATE 3639



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 11/102 (10%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG--- 1911
            +LSEGQ A ++CR+        R  W   G  LQ+      + + G   L +LT++    
Sbjct: 4260 QLSEGQDASFQCRLSRASGQEAR--WALGGVPLQANEMNDITVEQG--TLHLLTLHKVTL 4315

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            ED+G  +     ++G   S  +L V +K +++R  ++  ALE
Sbjct: 4316 EDAGTVSF----HVGTCSSEAQLKVTAKNTVVRGLENVEALE 4353



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/105 (24%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            VPP  +   ++  V +G+ V L+ +V      +V W K  +++QP  R +++ + G   +
Sbjct: 4623 VPPQPS-APESRQVAAGEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQ-GRQQM 4679

Query: 4572 LILEAY-PQDSGKYEC-VAINSAGEARCDAECVVSLPATKDKPKP 4614
            L+++ +  +D G+Y C +A  S   A    +  +S  +  + P+P
Sbjct: 4680 LVIKGFTAEDQGEYHCGLAQGSICPAAATFQVALSPASVDEAPQP 4724



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG-HRYRTVYDMGFVS 3888
            P F         +  + +R EC V  K D  +R  W ++G  L  G H +      G  S
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCS 4955

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L I  +   D+G Y C+  N FG+
Sbjct: 4956 LLIAGLDRADAGCYTCQVSNKFGQ 4979



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/86 (25%), Positives = 43/86 (50%), Gaps = 1/86 (1%)

Query: 4727 LRDIVVYEG-QPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
            LRD+ V  G + A+F+ ++     P + W ++G  +  +   +M  +     L I +   
Sbjct: 5266 LRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTR 5325

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            ED+G +    + A G   +SA+L+V+
Sbjct: 5326 EDSGQYAAYISNAMGAAYSSARLLVR 5351



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 10/151 (6%)

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPP--KFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            G+  E   E       D    +  VS P   KF++ + +   EE     F+C V P +  
Sbjct: 1869 GLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSD-- 1926

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             + + W+R+G LL    ++         SL I  +  ED+G+    A        + A +
Sbjct: 1927 -VAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAAL 1981

Query: 3920 SCKKLPDIILQNQVPRGM-KRSEALTQMEAT 3949
              ++ P +  +   P+ + +RS    ++E T
Sbjct: 1982 RVREAPVLFKKKLEPQTVEERSSVTLEVELT 2012



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 15/119 (12%)

Query: 751  EDYSKYQHQESIEEQTSQR-----PQFIRPLQDLGEL--QEGRNAHFEAQLTPVSDPTMR 803
            ED  +Y   ES ++ TS +     P+ ++ +  L  +  +EG  A F+  ++P SD  + 
Sbjct: 1873 EDAGEYVC-ESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP-SD--VA 1928

Query: 804  VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            V W++DG  +  S +     +    SL I  L  EDAG  TV A      A S+A++RV
Sbjct: 1929 VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAALRV 1983



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
            V +  P+  T  + +E K G+             A   V+WY ++ PL    +F  +   
Sbjct: 2463 VVSDIPVVLT--RPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEG 2520

Query: 1633 GFVALDIMSCLPEDSGTYTCRAINA 1657
                L I+  +P D+G Y C+A +A
Sbjct: 2521 QMAELRILRLMPADAGVYRCQAGSA 2545



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 772  FIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLN 831
            F++ L DL   + G  A  + +   VSDP   V W KDG  +  S +   +   G   L 
Sbjct: 2649 FLKALDDLSAEERGTLA-LQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV 2704

Query: 832  IMHLRAEDAGSYT 844
            +  +  EDAG YT
Sbjct: 2705 VHDVSPEDAGLYT 2717



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 42/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%)

Query: 393  QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
            +F +  +D +V EG      C ++    P V W   +  +R    +  L  E     L++
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYS-LRQEGAMLELVV 3243

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
             N+   DSG  +C      G+      L V      +  +F+ +       EG    L  
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVT----ALPAQFIGKLRNKEATEGATATLRC 3295

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
                + T  + W+K    +       +  DG    L I      DAA Y C    V G  
Sbjct: 3296 EL--SKTAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC----VCGEE 3349

Query: 573  ATRARL 578
             T A L
Sbjct: 3350 RTSASL 3355



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 8/119 (6%)

Query: 2883 GLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPD 2942
            GL  V+ AE + +    R S   T  P P   I      + +EG    L  ++  K  P 
Sbjct: 3333 GLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELS-KAAP- 3390

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
              +EW    + L  G R  L  D     L +  +   D+G Y+C      GE  TS+T+
Sbjct: 3391 --VEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVC----GEERTSATL 3443



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 9/101 (8%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV   P +F+  L N E VEG    L C L  V      VEW    + ++ G R+    
Sbjct: 3443 LTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAP----VEWRKGPENLRDGDRYILRQ 3498

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            E     L +  +   D+G Y C      G+  TS  L + A
Sbjct: 3499 EGTRCELQICGLAMADAGEYLCVC----GQERTSATLTIRA 3535



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 2373 RQRPV-FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431
            R  P+ FT+ L+N +   EG TA   C L  +      VEW++  + + D  R +   D 
Sbjct: 3622 RALPIKFTEGLRN-EEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDG 3676

Query: 2432 GYVSMTISHVRDEDEGVYMC 2451
                + I  +  ED G Y+C
Sbjct: 3677 ARCELQIRGLVAEDAGEYLC 3696



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
            +F + ++N E TEG    L   L+ +      VEW+     ++ G R     D     L 
Sbjct: 3627 KFTEGLRNEEATEGATAVLRCELSKMAP----VEWWKGHETLRDGDRHSLRQDGARCELQ 3682

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL 2080
            I    AED G Y+C      G+  T++ + V A    +++ L
Sbjct: 3683 IRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKFIEGL 3720



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 90/376 (23%), Positives = 143/376 (38%), Gaps = 34/376 (9%)

Query: 1305 ITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV  AP +F R L + E  EG   HL C L   G     VEW      +    +++   
Sbjct: 3972 LTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAG---ASVEWRKGSLQLFPCAKYQMVQ 4028

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK-DLILES--QHPSGLEK 1420
            +     L +  V  ED+G YTC   +   +++ S ++RV   K    L+S  Q    + +
Sbjct: 4029 DGAAAELLVRGVEQEDAGDYTCDTGHT--QSMASLSVRVPRPKFKTRLQSLEQETGDIAR 4086

Query: 1421 I-QYLEDTSRYKKTDIIDESVTIK--PRFVTRPKSI--ENVIEGQHVHFECKLEPVTDSN 1475
            +   L D         + E V +   P++  R +    E +I         +   VT   
Sbjct: 4087 LCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQ 4146

Query: 1476 LKVEWFKNGQP-VTIGHRFRPIHDFGYVALDIIDLIAEDS-----GIYTC-RAVNLVGTD 1528
                  +  +P VTI    R + D    A + ++   E S     G+  C + + L   +
Sbjct: 4147 KTAASLRVTEPEVTI---VRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNE 4203

Query: 1529 --EVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKN 1586
              EV+ R     T  +   T  +AG     +    S    T    EVT   P     L++
Sbjct: 4204 VTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEP-----LQD 4258

Query: 1587 VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV-ALDIMSCLPE 1645
            V++ EGQ A F+ RL   S    +  W     PL++      T   G +  L +     E
Sbjct: 4259 VQLSEGQDASFQCRLSRASGQ--EARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLE 4316

Query: 1646 DSGTYTCRAINALGEA 1661
            D+GT +        EA
Sbjct: 4317 DAGTVSFHVGTCSSEA 4332



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 59/240 (24%), Positives = 94/240 (39%), Gaps = 19/240 (7%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVS-LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            V+W +    L   +K  M   E  G    L++++ G  D GEY+C A +Q       V  
Sbjct: 1565 VTWYKDGKKLSSSSKVRM---EAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHV-A 1620

Query: 162  QPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDF 221
            +P+              +R V    E  A  T      Q+ QT+   Y +G   SS+   
Sbjct: 1621 EPK-----VVFAKEQPAHREVQ--AEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKV 1672

Query: 222  KVDTFEY-RLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKP-RNSKL-- 277
            +V+     R L      ++    Y  E+  Q        +  + P +I+++P R   L  
Sbjct: 1673 RVEAVGCTRRLVVQQAGQADAGEYSCEAGGQ-RLSFRLHVAELEP-QISERPCRREPLVV 1730

Query: 278  QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337
            +E  D      L+      VTW K+G  +  S +HE  +  +  TL V   Q  DS  Y+
Sbjct: 1731 KEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYS 1790



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 8/126 (6%)

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRR-----EDVEVAVNQAPRFITQLNGP 1853
            TL   ++  L  E      L     L+DS RY+           V V+  P    +    
Sbjct: 3134 TLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
             ++ EG +A   C +     P   V+W +   VL+ G +Y    +     L +  +  +D
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQD 3250

Query: 1914 SGEYTC 1919
            SG Y+C
Sbjct: 3251 SGRYSC 3256



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTC 4793
            G   + +  + SK     +WL++G  + +     +   G+    LLI      D G +TC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLIAGLDRADAGCYTC 4971

Query: 4794 RATTAAGQVETSAKLVV 4810
            + +   GQV  SA +VV
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W KDG+ + +SS++          L ++ V   DAG Y+C A    G    S  L I 
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRVSFQLHIT 1252

Query: 1003 TKKDIIAESQ 1012
              K + A+ Q
Sbjct: 1253 EPKAVFAKEQ 1262



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/119 (22%), Positives = 52/119 (43%), Gaps = 11/119 (9%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L +LG +  D+G Y C + +    A+++V +  V K       F + +  +   ++G  A
Sbjct: 1865 LTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVK-------FMSGLSTVVA-EEGGEA 1916

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             F+C V P    D+ + W+ +G  ++ S +           L I+     D+G+    A
Sbjct: 1917 TFQCVVSP---SDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEA 1972



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 2011 VEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            V+WY +  P+    +FK + +     L IL     D G Y C+A    G A +++ V V+
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 2071 AK 2072
            A+
Sbjct: 2555 AR 2556



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/140 (24%), Positives = 60/140 (42%), Gaps = 9/140 (6%)

Query: 2197 CTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256
            C L   GHR  +L T          + EA G  +   +      P RF   L+    V E
Sbjct: 3141 CQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSS-SIVRVHARPVRFQEALKDL-EVLE 3198

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            G  A   C +  V  P   +++ +    L+   ++ +  +   + L +++  P+D+G YS
Sbjct: 3199 GGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255

Query: 2317 VKAINALGHCTSAISMTVTA 2336
                 + G  T++ ++TVTA
Sbjct: 3256 C----SFGDQTTSATLTVTA 3271



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 7/97 (7%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P +F   +K   V E       C +     P   ++W     +L  G +Y    +   + 
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLE 3240

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L +  +  +DSG Y C     FG+  T AT++   LP
Sbjct: 3241 LVVRNLRPQDSGRYSC----SFGDQTTSATLTVTALP 3273



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 6/105 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P K  +  RN +  EG  A    +LS    P V W K  + L + ++H +    +   L+
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS-KAAP-VEWRKGHETLRDGDRHSLRQDGSRCELQ 3770

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
            +R     D+G Y+ +     G   TS  L V +    +++D ++Q
Sbjct: 3771 IRGLAVVDAGEYSCVC----GQERTSATLTVRALPARFIEDVKNQ 3811



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 6/96 (6%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG +A  +C +    +P   V W   G  LQ+  R         A L +  +  ED+GEY
Sbjct: 3903 EGSTATLQCELS---EPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            TC   +   QA S+      +    +R+ QH+   E
Sbjct: 3960 TCTCGS---QATSATLTVTAAPVRFLRELQHQEVDE 3992



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P   PP F  EL   T    G+T    C+V     P   I +Y +GKA+Q      +  D
Sbjct: 6009 PVWRPPDFEEELADCTAEL-GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIED 6065

Query: 2297 -FGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              G  +L +      D+G+Y   A +A G+C++
Sbjct: 6066 PDGSCALILDSLTGVDSGQYMCFAASAAGNCST 6098



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C +     P   V WY +GK L S  + R         L +  V   D+GEY+
Sbjct: 1181 GTTAMLSCEVA---QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYS 1237

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            C+A    GQ V S +L++   +++    Q
Sbjct: 1238 CEA---GGQRV-SFQLHITEPKAVFAKEQ 1262



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 1024 EDASRY---SKRTEEEVKITQK-PRFLGPLKGTNKIV--EGQSAHFEARVEPQSDLTMTV 1077
            EDA  Y   S+      ++T   PR +  + G + +V  EG  A F+  V P SD+   V
Sbjct: 1873 EDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSP-SDVA--V 1929

Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL 1129
             W+ +G  +  + +          +L I+ +  ED+G  TV A  A+  A L
Sbjct: 1930 VWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAAL 1981



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 4/62 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            ++W+K+   L+   + K + +  +  L I  L   D+G+Y C+A    G A S+  + +E
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTVE 2554

Query: 2736 DR 2737
             R
Sbjct: 2555 AR 2556



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF+  L+++  +E   +  +C V    DP   + W  +   L    +Y   H      L 
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEVS---DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV 2704

Query: 2835 ITHTYEEDSGIYTC 2848
            +     ED+G+YTC
Sbjct: 2705 VHDVSPEDAGLYTC 2718



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/49 (34%), Positives = 23/49 (46%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583
            V DP     W  +GV+L    ++   H  G   L ++ V   DAGLY C
Sbjct: 2670 VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC 2718



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 8/114 (7%)

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
            K T+    + KA  FT  L+N++ + E   A F  +   T+ P   V W      L+A  
Sbjct: 2904 KSTASLHVEEKANCFTEELTNLQ-VEEKGTAVFTCK---TEHPAATVTWRKGLLELRASG 2959

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            + +   +   + L IS     DS  Y C    + G+A + A + VQG+R  I+E
Sbjct: 2960 KHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLVQGRRVHIIE 3009



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 45/210 (21%), Positives = 75/210 (35%), Gaps = 22/210 (10%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            T  P +F    ++  + +EG  A     L  T      +EW    +T+    R       
Sbjct: 3270 TALPAQFIGKLRN-KEATEGATATLRCELSKTAP----VEWRKGSETLRDGDRYCLRQDG 3324

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
             M  L+I G    D+  YSC    +   A +++        +     F   +++ E + +
Sbjct: 3325 AMCELQIRGLAMVDAAEYSCVCGEERTSASLTI--------RPMPAHFIGRLRHQESI-E 3375

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G +A   C +         +EW    + +R   R     D     L I      D+GEY 
Sbjct: 3376 GATATLRCEL----SKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYS 3431

Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
            C      GE+ T AT+        + E L+
Sbjct: 3432 CVC----GEERTSATLTVKALPAKFTEGLR 3457



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 13/119 (10%)

Query: 1439 SVTIKP---RFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            S+TI+P    F+ R +  E+ IEG      C+L         VEW K  + +  G R   
Sbjct: 3354 SLTIRPMPAHFIGRLRHQES-IEGATATLRCELSKAAP----VEWRKGRESLRDGDRHSL 3408

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLE 1553
              D     L I  L   D+G Y+C    + G +  S  LT ++         +NE  +E
Sbjct: 3409 RQDGAVCELQICGLAVADAGEYSC----VCGEERTSATLTVKALPAKFTEGLRNEEAVE 3463



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 8/101 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + + P KF   +++    E       C +  K  P   +EW +  + L  G RY    + 
Sbjct: 3445 VKALPAKFTEGLRNEEAVEGATAMLWCELS-KVAP---VEWRKGPENLRDGDRYILRQEG 3500

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
                L I  +   D+GEY+C      G++ T AT++ + LP
Sbjct: 3501 TRCELQICGLAMADAGEYLCVC----GQERTSATLTIRALP 3537



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/90 (24%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P+F   L+S  +  EG    L+ ++   ++P   + W K G+ L    R +         
Sbjct: 3890 PVFREPLQSL-QAEEGSTATLQCEL---SEPTATVVWSKGGLQLQANGRREPRLQGCTAE 3945

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            L +  L+ +D+G YTC   +    A  T +
Sbjct: 3946 LVLQDLQREDTGEYTCTCGSQATSATLTVT 3975



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 10/100 (10%)

Query: 1315 RALHNIETVEGTNVHLECRL-QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV--ALD 1371
            R L N+E +EG     EC+L QP   +     W  + +P++T       +  + +   L 
Sbjct: 4344 RGLENVEALEGGEALFECQLSQP---EVAAHTWLLDDEPVRTSENAEVVFFENGLRHLLL 4400

Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILE 1411
            L ++ P+DS    C+ T   G+ VTS  L V   +  ILE
Sbjct: 4401 LKNLRPQDS----CRVTFLAGDMVTSAFLTVRGWRLEILE 4436



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/118 (26%), Positives = 51/118 (43%), Gaps = 6/118 (5%)

Query: 2087 KIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWF 2146
            KIQ   K  + +   ++Q G  P+F       E  + GD    EC V    D  +   W 
Sbjct: 4878 KIQAAFKGYKVRKEMKQQEG--PMFSHTFGDTE-AQVGDALRLECVVASKAD--VRARWL 4932

Query: 2147 HNGQKIRAG-HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
             +G ++  G H +      G  +L I      D+G Y C+ +NK G+  ++  + V+G
Sbjct: 4933 KDGVELTDGRHHHIDQLGDGTCSLLIAGLDRADAGCYTCQVSNKFGQVTHSACVVVSG 4990



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 5/77 (6%)

Query: 3576 HFECRLIP-VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
            H E +L+  ++D +  V W  +G+ L  G + +     G  +L +  V + DAGLY C  
Sbjct: 721  HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC-- 778

Query: 3635 TNRHGEATVSCKLQVKG 3651
             +R G   ++ +L V+G
Sbjct: 779  VSRGGR--IAYQLSVQG 793



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 13/45 (28%), Positives = 21/45 (46%)

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
           +TW KDG  + P P+  +    G   L +      DA  Y+C ++
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSR 781



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 16/51 (31%), Positives = 26/51 (50%)

Query: 797  VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
            V+ P   V WYKDG+ +++SS++          L +  +   DAG Y+  A
Sbjct: 1190 VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 4/77 (5%)

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            +  +   V W KDG+ + +SS++          L ++     DAG YTC A    G    
Sbjct: 1282 VAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRL 1337

Query: 996  SANLTIVTKKDIIAESQ 1012
            S +L +   K + A+ Q
Sbjct: 1338 SFHLDVSEPKAVFAKEQ 1354



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/94 (26%), Positives = 36/94 (38%), Gaps = 7/94 (7%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            KP       D +S +E G    +     + D    V W KDG  +  S +       G  
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCE---VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTR 2701

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L +  V+  DAG YTC     +G   T A + +
Sbjct: 2702 GLVVHDVSPEDAGLYTCH----VGSEETRARVRV 2731



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 7/87 (8%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            GE+      L+    P   V W  + K+++   ++   C+    +L I     +D+GEY 
Sbjct: 2841 GEDVELRCELSRAGTP---VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYT 2897

Query: 3495 CRAYNNYGEAVTTASMKVQGKRNIILE 3521
            C        + +TAS+ V+ K N   E
Sbjct: 2898 CEV----EASKSTASLHVEEKANCFTE 2920



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG      C +     P   ++W + N  L  G +Y    + + + L +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSSVAAP---VKWCYGNNVLRPGDKYSLRQEGAMLELVV 3243

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
             +   +DSG Y+C    S G  TTS +L  T
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVT 3270



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P  F +  KN    +G  A  + +L  N    V W +    L + ++YS+R  +      
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLR--QDGTKCE 3592

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163
            L I+ +   D GEY+C    +   A+ +V   P
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALP 3625



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 4/83 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  + N   +EG     +C +  +      +EW   ++ L  G RY    D +   L I
Sbjct: 3804 FIEDVKNQEAREGATAVLQCELSKAAP----VEWRKGSETLRGGDRYSLRQDGTRCELQI 3859

Query: 2836 THTYEEDSGIYTCKATNSKGSAT 2858
                  D+G Y+C     + SAT
Sbjct: 3860 HGLSVADTGEYSCVCGQERTSAT 3882



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 9/102 (8%)

Query: 1690 QLEDTSKY-----QRHSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLR 1743
            Q EDT +Y      + ++    +T APV F   ++   V E   AH    L   G     
Sbjct: 3952 QREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAG---AS 4008

Query: 1744 VEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785
            VEW +  + +    +   + D     L ++ V  ED+G YTC
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC 4050



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG-HR 1358
            Q R  + V + P F   L +     G  V L CR+   G     + W+ +GK ++   H 
Sbjct: 6003 QQRLALPVWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHH 6060

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                      AL L S+   DSG Y C A +  G   T
Sbjct: 6061 ILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCST 6098



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 943  VEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+ V+     I      G  AL + S+T  D+G Y C A +A G  +T   + +
Sbjct: 6045 ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104


>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
          Length = 1496

 Score =  124 bits (298), Expect = 1e-26
 Identities = 106/401 (26%), Positives = 159/401 (39%), Gaps = 36/401 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P  T + Q   V       F    +G P P I W R N  +    D +++     + L+I
Sbjct: 263  PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGT-LMI 321

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            +     D  ++  +A+N  G  K       +E   +  G    P+F +  QN  V  G+ 
Sbjct: 322  QNTQETDQGIYQCMAKNVAGEVK------TQEVTLRYFGSPARPTFVIQPQNTEVLVGES 375

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQP-DIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
            V L+   TG  P  + W +  +   P D R  I    G Y   +++    DSG+Y C A 
Sbjct: 376  VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQG---DSGEYACSAT 432

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N+       A  +V                 A P+     +D++V EGQ ++F C+  G 
Sbjct: 433  NNIDSVHATAFIIVQ----------------ALPQFTVTPQDRVVIEGQTVDFQCEAKGN 476

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P P + W KG   +   +   +  +    TLRIS     D+G Y+C A N  G   V A 
Sbjct: 477  PPPVIAWTKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAH 533

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            L V QP +   + A  P  D  V  G   Q       + +P I W ++G  + E+  F +
Sbjct: 534  LTV-QP-RVTPVFASIP-SDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHI 590

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              EG    L I +    D G + C A    G    S  L V
Sbjct: 591  SPEG---FLTINDVGPADAGRYECVARNTIGSASVSMVLSV 628



 Score =  103 bits (247), Expect = 2e-20
 Identities = 94/346 (27%), Positives = 140/346 (40%), Gaps = 35/346 (10%)

Query: 4376 KEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFD 4435
            +E  + I       +  + +TQE  +     P++P  F  + Q   V   E    E    
Sbjct: 325  QETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPT-FVIQPQNTEVLVGESVTLECSAT 383

Query: 4436 GEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            G P P I W R +  P+   P   I   +    L I+ V   DS  +A  A N   +   
Sbjct: 384  GHPPPRISWTRGDRTPLPVDPRVNI---TPSGGLYIQNVVQGDSGEYACSATNNIDSVHA 440

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            +A ++V+            P FT+T Q+  V  GQ V    +  G  P  + W K G ++
Sbjct: 441  TAFIIVQAL----------PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQL 490

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
              D R+ +L      TL I      D G+YEC A+N  G  +  A   V       +P+ 
Sbjct: 491  SVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTV-------QPRV 540

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
                A+ P        D  V  G  ++  C   G+P P + W K    +  S  F +S  
Sbjct: 541  TPVFASIP-------SDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHIS-- 591

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
              E  L I++  P D G Y+CVA N+ G  +V+  L V  PD + N
Sbjct: 592  -PEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRN 636



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 77/301 (25%), Positives = 124/301 (41%), Gaps = 25/301 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P  T   Q+ +VTSG  V    +  G    ++ WL+N  ++     +++ L +DG  TL+
Sbjct: 263  PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--TLM 320

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            I      D G Y+C+A N AGE +           T++       +   P  +I+P   +
Sbjct: 321  IQNTQETDQGIYQCMAKNVAGEVK-----------TQEVTLRYFGSPARPTFVIQPQNTE 369

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            ++  G+++   C   G P P + W +GD+   P              L I      D G+
Sbjct: 370  VLV-GESVTLECSATGHPPPRISWTRGDR--TPLPVDPRVNITPSGGLYIQNVVQGDSGE 426

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
            Y C A N+   V   A + V    QA     +TP +D VV EGQ   F+ +      P I
Sbjct: 427  YACSATNNIDSVHATAFIIV----QALPQFTVTP-QDRVVIEGQTVDFQCEAKGNPPPVI 481

Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             W + G+ +       ++  G    L I      D G + C+A    G  +  A L V+ 
Sbjct: 482  AWTKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQP 538

Query: 4813 K 4813
            +
Sbjct: 539  R 539



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 57/177 (32%), Positives = 82/177 (46%), Gaps = 7/177 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+     QD DVT G    F CR  G P PE+ W  N+ ++    + ++ + + G   LM
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--TLM 320

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N   +D G+  C+A+N +GE   Q  + +        P FV +     V  GE V L 
Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQ-EVTLRYFGSPARPTFVIQPQNTEVLVGESVTLE 379

Query: 512 ARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
             A G P PRI+W + D  P+  +P + I   GG   L I      D+  Y C+A N
Sbjct: 380 CSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG---LYIQNVVQGDSGEYACSATN 433



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 76/241 (31%), Positives = 98/241 (40%), Gaps = 15/241 (6%)

Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD-TQQRETEERIEISEKALAP 392
           G  T L  +P   I  SG L +++     VQ    +Y    T   ++            P
Sbjct: 395 GDRTPLPVDPRVNITPSGGLYIQN----VVQGDSGEYACSATNNIDSVHATAFIIVQALP 450

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           QF    QDR V EG+   F C   G P P + W     Q+  D  H  LV  SG   L I
Sbjct: 451 QFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH--LVLSSG--TLRI 506

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
           + V L D G   C A N  G       L V   +  V P F    S   V  G  V L  
Sbjct: 507 SGVALHDQGQYECQAVNIIGSQKVVAHLTV---QPRVTPVFASIPSDTTVEVGANVQLPC 563

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            + G P P ITW KDGV +  + +  I  +G  +  D+  A   DA  Y+C A+N  GS 
Sbjct: 564 SSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPA---DAGRYECVARNTIGSA 620

Query: 573 A 573
           +
Sbjct: 621 S 621



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 79/313 (25%), Positives = 123/313 (39%), Gaps = 41/313 (13%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+I  +P+++ +  G    F  +  GNP+P + W +N   L +      +   +  TL +
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNEL-SMKTDSRLNLLDDGTLMI 321

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
           +NTQ++D G Y  +A+N  G + T      E     +    R  ++              
Sbjct: 322 QNTQETDQGIYQCMAKNVAGEVKTQ-----EVTLRYFGSPARPTFV-------------- 362

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
               + PQ  +V     VT       +C  TG P P ++W   DR      + ++ +  S
Sbjct: 363 ----IQPQNTEVLVGESVT------LECSATGHPPPRISWTRGDRTPL-PVDPRVNITPS 411

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
           G   L I NV   DSG   C A N   ++       +++      P+F        V EG
Sbjct: 412 G--GLYIQNVVQGDSGEYACSATNNI-DSVHATAFIIVQ----ALPQFTVTPQDRVVIEG 464

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           + V     A G P P I W K G  +  +   R H    + TL I      D   Y+C A
Sbjct: 465 QTVDFQCEAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 521

Query: 566 QNVAGSTATRARL 578
            N+ GS    A L
Sbjct: 522 VNIIGSQKVVAHL 534



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 73/321 (22%), Positives = 117/321 (36%), Gaps = 28/321 (8%)

Query: 48  MTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR 107
           M   V      Q +T    G P+ P F    +N     G +   E    G+P P +SWTR
Sbjct: 335 MAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR 394

Query: 108 -KKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGX 166
             + PL    + ++     T    L I+ +  GD GEY C+A N       + +I  +  
Sbjct: 395 GDRTPLPVDPRVNI-----TPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL 449

Query: 167 XXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTD--DFKVD 224
                            +TV+ +          +      +A+T G    S D     + 
Sbjct: 450 PQFTVTPQDRVVIE--GQTVDFQCEA-------KGNPPPVIAWTKGGSQLSVDRRHLVLS 500

Query: 225 TFEYRL----LREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEG 280
           +   R+    L +    E      +G   V     +   + PV     A  P ++ ++ G
Sbjct: 501 SGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPV----FASIPSDTTVEVG 556

Query: 281 ADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLA 340
           A+ Q      G P P +TW K+G ++  S K  I        L + +   +D+G Y  +A
Sbjct: 557 ANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHI---SPEGFLTINDVGPADAGRYECVA 613

Query: 341 ENPNGCIVTSGYLAVESPTES 361
            N  G    S  L+V  P  S
Sbjct: 614 RNTIGSASVSMVLSVNVPDVS 634



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 8/94 (8%)

Query: 2368 PEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRN--EKLIEDSSRI 2425
            PE +  +RP  T   Q+ D +  G T +F CR    G+P  ++ W RN  E  ++  SR+
Sbjct: 255  PEELNCERPRITSEPQDAD-VTSGNTVYFTCRA--EGNPKPEIIWLRNNNELSMKTDSRL 311

Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                D    ++ I + ++ D+G+Y C A N+ GE
Sbjct: 312  NLLDDG---TLMIQNTQETDQGIYQCMAKNVAGE 342



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 52/228 (22%), Positives = 86/228 (37%), Gaps = 22/228 (9%)

Query: 3075 TGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            TG     I W    +T +    R+    + G+ +  ++     DSG Y+C ATN      
Sbjct: 383  TGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVV---QGDSGEYACSATNNIDSVH 439

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
             +  +          P+FT   Q+   + +GQ+  F+C      +P   I W   G  + 
Sbjct: 440  ATAFIIVQ-----ALPQFTVTPQD-RVVIEGQTVDFQCEAK--GNPPPVIAWTKGGSQLS 491

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
               R   +S     +  +A    HD G+Y C+A N  G     A +    +      S+ 
Sbjct: 492  VDRRHLVLSSGTLRISGVAL---HDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIP 548

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAH 3301
             D+  ++       GA  Q P +   EP   IT  +D  ++ E    H
Sbjct: 549  SDTTVEV-------GANVQLPCSSQGEPEPAITWNKDGVQVTESGKFH 589



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 43/130 (33%), Positives = 58/130 (44%), Gaps = 12/130 (9%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA--TGS 3742
            IT E+     PR T E +D  DV  G  V+F CR E  G+P   I W  N    +  T S
Sbjct: 253  ITPEELNCERPRITSEPQD-ADVTSGNTVYFTCRAE--GNPKPEIIWLRNNNELSMKTDS 309

Query: 3743 RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT---TAKITCS-AKRDIVLESQ 3798
            R++ L+D     L I      D G Y C A N  G   T   T +   S A+   V++ Q
Sbjct: 310  RLNLLDDG---TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQ 366

Query: 3799 LPQGMSGEKI 3808
              + + GE +
Sbjct: 367  NTEVLVGESV 376



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 46/190 (24%), Positives = 73/190 (38%), Gaps = 12/190 (6%)

Query: 3040 PDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRT 3099
            P++     P  T+  +D  D++ G   ++       G+    I W  N   +      R 
Sbjct: 255  PEELNCERPRITSEPQD-ADVTSGNTVYFTCRA--EGNPKPEIIWLRNNNELSMKTDSR- 310

Query: 3100 VYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159
            +       L I  T+ TD G Y C A N  G+ + + ++         +P F    QN E
Sbjct: 311  LNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVK-TQEVTLRYFGSPARPTFVIQPQNTE 369

Query: 3160 GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ-PMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
             L  G+S   EC+      P  +I W    + P+    R+      G  + ++      D
Sbjct: 370  VLV-GESVTLECSA--TGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVV---QGD 423

Query: 3219 SGEYVCRAYN 3228
            SGEY C A N
Sbjct: 424  SGEYACSATN 433



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           PQF V  +    +EG  + F+   E  G+P   I W K G  +    R   +   G + +
Sbjct: 450 PQFTVTPQDRVVIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRHL-VLSSGTLRI 506

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             ++L+  D G+Y C+AV+  G  +  A L V PR T
Sbjct: 507 SGVALH--DQGQYECQAVNIIGSQKVVAHLTVQPRVT 541



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 11/123 (8%)

Query: 3544 TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL--L 3601
            +V T+TPE  +   P  T+ P D  ++  ++ +F CR     +    + W  N   L   
Sbjct: 249  SVATITPEELNCERPRITSEPQDADVTSGNTVYFTCR--AEGNPKPEIIWLRNNNELSMK 306

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA-TVSCKLQVKG---RQGIIL 3657
            T SR+  ++D G ++++     + D G+Y C A N  GE  T    L+  G   R   ++
Sbjct: 307  TDSRLNLLDD-GTLMIQ--NTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVI 363

Query: 3658 EPQ 3660
            +PQ
Sbjct: 364  QPQ 366



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 7/111 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+F   P+    VIEGQ V F+C  E   +    + W K G  +++  R   +       
Sbjct: 450  PQFTVTPQD-RVVIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG---T 503

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR-STTDIVRSTQNEAGLE 1553
            L I  +   D G Y C+AVN++G+ +V   LT +   T +  S  ++  +E
Sbjct: 504  LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVE 554



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 8/111 (7%)

Query: 3681 KREEITIED-EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR-PF 3738
            K +E+T+     P  P F ++   N +V  G  V  +C     G P  RI W    R P 
Sbjct: 344  KTQEVTLRYFGSPARPTFVIQ-PQNTEVLVGESVTLECSA--TGHPPPRISWTRGDRTPL 400

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
                RV+     G   L I  +   D+GEY C ATN   S   TA I   A
Sbjct: 401  PVDPRVNITPSGG---LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 448



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 6/92 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+FTV  +D + V EG  V F C  E  G+P   I W   G   +   R H +   G   
Sbjct: 450  PQFTVTPQDRV-VIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRR-HLVLSSG--T 503

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            L I  +   D G+Y C+A N  GS    A +T
Sbjct: 504  LRISGVALHDQGQYECQAVNIIGSQKVVAHLT 535



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 8/119 (6%)

Query: 2638 VQQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            VQ  P FT  +   D++V EGQ V  + Q E + +P   I W K G  L+   R      
Sbjct: 446  VQALPQFT--VTPQDRVVIEGQTV--DFQCEAKGNPPPVIAWTKGGSQLSVDRR-HLVLS 500

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGA 2755
             G  TL I+ +   D G Y C+A N++G     A + ++ R   +  S+  D+   +GA
Sbjct: 501  SG--TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGA 557



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 9/85 (10%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN--TIVN 4153
            +TPE++  E      P   S P    V  G    F CR  G+PKP ++WL N N  ++  
Sbjct: 253  ITPEELNCER-----PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKT 307

Query: 4154 GSRYKLTYDGMYHFDIPKTRQYDTG 4178
             SR  L  DG     I  T++ D G
Sbjct: 308  DSRLNLLDDGT--LMIQNTQETDQG 330



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/129 (22%), Positives = 56/129 (43%), Gaps = 4/129 (3%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + + K   GE   Q  T   R  G  + P    +P+N+++  G     +   +G+P PR+
Sbjct: 333 QCMAKNVAGEVKTQEVTL--RYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRI 390

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
           +W +  +  +  +    IT      L ++N  + DSG Y   A N    +  + ++ V++
Sbjct: 391 SWTRGDRTPLPVDPRVNITPSG--GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 448

Query: 358 PTESYVQDQ 366
             +  V  Q
Sbjct: 449 LPQFTVTPQ 457



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 5/95 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+FT TP D ++ E  +  F+C      +    + W   G  L    R   ++      L
Sbjct: 450  PQFTVTPQDRVVIEGQTVDFQCE--AKGNPPPVIAWTKGGSQLSVDRRHLVLSS---GTL 504

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             I GV   D G Y C+A N  G   V   L V+ R
Sbjct: 505  RISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR 539



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/92 (25%), Positives = 36/92 (39%), Gaps = 2/92 (2%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF 4167
            R  PVF S+P   TVE G   +  C   G P+P + W  +G  +    ++ ++ +G    
Sbjct: 539  RVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGF--L 596

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199
             I      D G+ E +             L V
Sbjct: 597  TINDVGPADAGRYECVARNTIGSASVSMVLSV 628



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           + P F  +  D  V  G   +  C   G P P +TW  +  Q+ +  + K  ++  G   
Sbjct: 540 VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTE--SGKFHISPEG--F 595

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           L I +V  +D+G   CVARN  G  +    L+V
Sbjct: 596 LTINDVGPADAGRYECVARNTIGSASVSMVLSV 628



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 6/93 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+F    +D++ I EG    F+   E  G+    + W K G  +    R     +     
Sbjct: 450  PQFTVTPQDRVVI-EGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG---T 503

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I  V +HD G Y C+A N IG     A+LT+
Sbjct: 504  LRISGVALHDQGQYECQAVNIIGSQKVVAHLTV 536



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 7/115 (6%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS-VTVGSRFKTYYD 1231
            S ++P FV    N   V  G+++ LEC     G P  R+ W    R+ + V  R      
Sbjct: 355  SPARPTFVIQPQNTE-VLVGESVTLEC--SATGHPPPRISWTRGDRTPLPVDPRVNITPS 411

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286
             G    +++     D+GEY   A N++ S H +A + V          Q+   IE
Sbjct: 412  GGLYIQNVVQG---DSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIE 463



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV   P+F    +   V E + V F+C  E K +P   I W + G  L    R+  V   
Sbjct: 445  IVQALPQFTVTPQDRVVIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRH-LVLSS 501

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911
            G  +L I  V   D G+Y C+AVN  G
Sbjct: 502  G--TLRISGVALHDQGQYECQAVNIIG 526



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            PVF   + +   V  G N+ L C  +  G+P   + W  +G  VT   +F    + GF+ 
Sbjct: 542  PVFAS-IPSDTTVEVGANVQLPCSSQ--GEPEPAITWNKDGVQVTESGKFHISPE-GFLT 597

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            ++ +    AD G Y   A N +GSA  S ++ V
Sbjct: 598  INDVGP--ADAGRYECVARNTIGSASVSMVLSV 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            PVF     D  V     A+ +      G+P+  + W ++GV +  S +     + G++ +
Sbjct: 542  PVFASIPSDTTV--EVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPE-GFLTI 598

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            N   V P D+G Y C A N +G A  S  L V
Sbjct: 599  ND--VGPADAGRYECVARNTIGSASVSMVLSV 628



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 6/103 (5%)

Query: 1706 VITQA-PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            +I QA P FT+  +D  V E Q   F+      G+P   + W + G  +    R   +  
Sbjct: 444  IIVQALPQFTVTPQDRVVIEGQTVDFQCEA--KGNPPPVIAWTKGGSQLSVDRRHLVLSS 501

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
                 L +  V   D G Y C+A+N +G     + L VQ + +
Sbjct: 502  G---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVT 541



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 7/95 (7%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG--VPIEASNRLTT 1761
            +E+  + P  T   +D  V      +F  R    G+PK  + WLRN   + ++  +RL  
Sbjct: 256  EELNCERPRITSEPQDADVTSGNTVYFTCRA--EGNPKPEIIWLRNNNELSMKTDSRLNL 313

Query: 1762 MHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            + D     L ++     D G Y C A N  GE  T
Sbjct: 314  LDDG---TLMIQNTQETDQGIYQCMAKNVAGEVKT 345



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 9/97 (9%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG--VTLTTGARLKSTFDF 2697
            + P  T+  +  D +  G  VY   + E    P  +I W +N   +++ T +RL +  D 
Sbjct: 261  ERPRITSEPQDAD-VTSGNTVYFTCRAEGNPKP--EIIWLRNNNELSMKTDSRL-NLLDD 316

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  TL I + +  D GIY C A N+ GE V T  + +
Sbjct: 317  G--TLMIQNTQETDQGIYQCMAKNVAGE-VKTQEVTL 350



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/104 (31%), Positives = 40/104 (38%), Gaps = 6/104 (5%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL-LPSGHRYRTVYDMGFVS 3888
            P F+ Q ++  V   E V  EC       P  RI W R  +  LP   R       G   
Sbjct: 359  PTFVIQPQNTEVLVGESVTLECSATGHPPP--RISWTRGDRTPLPVDPRVNITPSGG--- 413

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            L I  V   DSGEY C A N+       A I  + LP   +  Q
Sbjct: 414  LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQ 457



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 3/76 (3%)

Query: 79  KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
           ++A    G    F  +  GNP P + W R    L    K   R N    D +L+I+    
Sbjct: 270 QDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNEL--SMKTDSRLN-LLDDGTLMIQNTQE 326

Query: 139 GDEGEYTCTARNQYGE 154
            D+G Y C A+N  GE
Sbjct: 327 TDQGIYQCMAKNVAGE 342



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+ ++F C  E +  P  +I W  NN  L   T  +  +     +L I +T E D GIY 
Sbjct: 277  GNTVYFTCRAEGNPKP--EIIWLRNNNELSMKTDSR-LNLLDDGTLMIQNTQETDQGIYQ 333

Query: 2848 CKATNSKGSATT 2859
            C A N  G   T
Sbjct: 334  CMAKNVAGEVKT 345



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 9/113 (7%)

Query: 3147 QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP--MRHSTRIKTVSDF 3204
            ++PR T+  Q+ + +  G + +F C      +P  +I W  N     M+  +R+  + D 
Sbjct: 261  ERPRITSEPQDAD-VTSGNTVYFTCRAE--GNPKPEIIWLRNNNELSMKTDSRLNLLDDG 317

Query: 3205 GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR-ATINCYGKGGVYLESLQPDS 3256
                L I  TQ  D G Y C A N  GE  T+  T+  +G        +QP +
Sbjct: 318  ---TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQN 367



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 1322 TVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
            TVE G NV L C  Q  G+    + W  +G  +    +F  + E     L +  V P D+
Sbjct: 552  TVEVGANVQLPCSSQ--GEPEPAITWNKDGVQVTESGKFHISPEG---FLTINDVGPADA 606

Query: 1381 GVYTCQATNQLGEAVTSCALRV 1402
            G Y C A N +G A  S  L V
Sbjct: 607  GRYECVARNTIGSASVSMVLSV 628



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 6/96 (6%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGR-PVQQGHRFKTTYDFGYV 2035
            +P F    +N EV  G  V LE + T    P  R+ W    R P+    R   T   G  
Sbjct: 358  RPTFVIQPQNTEVLVGESVTLECSAT--GHPPPRISWTRGDRTPLPVDPRVNITPSGGLY 415

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
              +++     D+G Y C ATN +     T+ + V A
Sbjct: 416  IQNVVQG---DSGEYACSATNNIDSVHATAFIIVQA 448



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 7/96 (7%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV-LQSGHRYRTSNDFGFA 1902
            P F+ Q    T++  G+S   EC    +P P  R+ W    +  L    R   +   G  
Sbjct: 359  PTFVIQPQN-TEVLVGESVTLECSATGHPPP--RISWTRGDRTPLPVDPRVNITPSGG-- 413

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
             L I  V   DSGEY C A NN+    ++  + VQ+
Sbjct: 414  -LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 448



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 5/82 (6%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EGQ+  ++C  +  P P   + W   G  L    R+   +      L I  V   D G+Y
Sbjct: 463  EGQTVDFQCEAKGNPPPV--IAWTKGGSQLSVDRRHLVLSS---GTLRISGVALHDQGQY 517

Query: 1918 TCKAINNLGQAVSSIRLNVQSK 1939
             C+A+N +G       L VQ +
Sbjct: 518  ECQAVNIIGSQKVVAHLTVQPR 539



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G+    + W KDG  V  S +       G+  LTI  V   DAG Y C A N IG A+ S
Sbjct: 567  GEPEPAITWNKDGVQVTESGKFHISPE-GF--LTINDVGPADAGRYECVARNTIGSASVS 623

Query: 997  ANLTI 1001
              L++
Sbjct: 624  MVLSV 628



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/40 (40%), Positives = 17/40 (42%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT 4150
            P FV  P    V  GE     C  TGHP PR+ W     T
Sbjct: 359  PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRT 398



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 5/92 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F + PSD  +   ++    C      +    + W  +G  +    +   I+  GF  L
Sbjct: 542  PVFASIPSDTTVEVGANVQLPCS--SQGEPEPAITWNKDGVQVTESGKFH-ISPEGF--L 596

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I  V   DAG Y C A N  G A+VS  L V
Sbjct: 597  TINDVGPADAGRYECVARNTIGSASVSMVLSV 628



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 6/83 (7%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P+F  +   PS+      A+ +      G+P     W  +GV++    +F  + + GF+T
Sbjct: 542  PVFASI---PSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPE-GFLT 597

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
              IN V   DAG Y C A N  G
Sbjct: 598  --INDVGPADAGRYECVARNTIG 618



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 6/119 (5%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            + +P+  I W  +G  + +  +F ++ + GF+T++  DV   D+G Y C A N  G A  
Sbjct: 566  QGEPEPAITWNKDGVQVTESGKFHISPE-GFLTIN--DVGPADAGRYECVARNTIGSASV 622

Query: 2998 SSTVYCTSKDNLIERTQHP-KGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFK 3055
            S  +     D  + R   P   T  +E I  ++ ++        D     P +   +F+
Sbjct: 623  SMVLSVNVPD--VSRNGDPFVATSIVEAIATVDRAINSTRTHLFDSRPRSPNDLLALFR 679



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 8/91 (8%)

Query: 3695 PRFT---VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG 3751
            PR T     I  +  V  G  V   C  +  G+P   I W  +G       + H ++  G
Sbjct: 538  PRVTPVFASIPSDTTVEVGANVQLPCSSQ--GEPEPAITWNKDGVQVTESGKFH-ISPEG 594

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            F  L I+ +   DAG Y C A N  GSA+ +
Sbjct: 595  F--LTINDVGPADAGRYECVARNTIGSASVS 623


>BC098579-1|AAH98579.1|  722|Homo sapiens PXDN protein protein.
          Length = 722

 Score =  124 bits (298), Expect = 1e-26
 Identities = 106/401 (26%), Positives = 159/401 (39%), Gaps = 36/401 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P  T + Q   V       F    +G P P I W R N  +    D +++     + L+I
Sbjct: 241  PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGT-LMI 299

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            +     D  ++  +A+N  G  K       +E   +  G    P+F +  QN  V  G+ 
Sbjct: 300  QNTQETDQGIYQCMAKNVAGEVK------TQEVTLRYFGSPARPTFVIQPQNTEVLVGES 353

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQP-DIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
            V L+   TG  P  + W +  +   P D R  I    G Y   +++    DSG+Y C A 
Sbjct: 354  VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQG---DSGEYACSAT 410

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N+       A  +V                 A P+     +D++V EGQ ++F C+  G 
Sbjct: 411  NNIDSVHATAFIIVQ----------------ALPQFTVTPQDRVVIEGQTVDFQCEAKGN 454

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P P + W KG   +   +   +  +    TLRIS     D+G Y+C A N  G   V A 
Sbjct: 455  PPPVIAWTKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAH 511

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            L V QP +   + A  P  D  V  G   Q       + +P I W ++G  + E+  F +
Sbjct: 512  LTV-QP-RVTPVFASIP-SDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHI 568

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              EG    L I +    D G + C A    G    S  L V
Sbjct: 569  SPEG---FLTINDVGPADAGRYECVARNTIGSASVSMVLSV 606



 Score =  103 bits (247), Expect = 2e-20
 Identities = 94/346 (27%), Positives = 140/346 (40%), Gaps = 35/346 (10%)

Query: 4376 KEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFD 4435
            +E  + I       +  + +TQE  +     P++P  F  + Q   V   E    E    
Sbjct: 303  QETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPT-FVIQPQNTEVLVGESVTLECSAT 361

Query: 4436 GEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            G P P I W R +  P+   P   I   +    L I+ V   DS  +A  A N   +   
Sbjct: 362  GHPPPRISWTRGDRTPLPVDPRVNI---TPSGGLYIQNVVQGDSGEYACSATNNIDSVHA 418

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            +A ++V+            P FT+T Q+  V  GQ V    +  G  P  + W K G ++
Sbjct: 419  TAFIIVQAL----------PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQL 468

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
              D R+ +L      TL I      D G+YEC A+N  G  +  A   V       +P+ 
Sbjct: 469  SVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTV-------QPRV 518

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
                A+ P        D  V  G  ++  C   G+P P + W K    +  S  F +S  
Sbjct: 519  TPVFASIP-------SDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHIS-- 569

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
              E  L I++  P D G Y+CVA N+ G  +V+  L V  PD + N
Sbjct: 570  -PEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRN 614



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 77/301 (25%), Positives = 124/301 (41%), Gaps = 25/301 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P  T   Q+ +VTSG  V    +  G    ++ WL+N  ++     +++ L +DG  TL+
Sbjct: 241  PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--TLM 298

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            I      D G Y+C+A N AGE +           T++       +   P  +I+P   +
Sbjct: 299  IQNTQETDQGIYQCMAKNVAGEVK-----------TQEVTLRYFGSPARPTFVIQPQNTE 347

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            ++  G+++   C   G P P + W +GD+   P              L I      D G+
Sbjct: 348  VLV-GESVTLECSATGHPPPRISWTRGDR--TPLPVDPRVNITPSGGLYIQNVVQGDSGE 404

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
            Y C A N+   V   A + V    QA     +TP +D VV EGQ   F+ +      P I
Sbjct: 405  YACSATNNIDSVHATAFIIV----QALPQFTVTP-QDRVVIEGQTVDFQCEAKGNPPPVI 459

Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             W + G+ +       ++  G    L I      D G + C+A    G  +  A L V+ 
Sbjct: 460  AWTKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQP 516

Query: 4813 K 4813
            +
Sbjct: 517  R 517



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 57/177 (32%), Positives = 82/177 (46%), Gaps = 7/177 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+     QD DVT G    F CR  G P PE+ W  N+ ++    + ++ + + G   LM
Sbjct: 241 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--TLM 298

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N   +D G+  C+A+N +GE   Q  + +        P FV +     V  GE V L 
Sbjct: 299 IQNTQETDQGIYQCMAKNVAGEVKTQ-EVTLRYFGSPARPTFVIQPQNTEVLVGESVTLE 357

Query: 512 ARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
             A G P PRI+W + D  P+  +P + I   GG   L I      D+  Y C+A N
Sbjct: 358 CSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG---LYIQNVVQGDSGEYACSATN 411



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 76/241 (31%), Positives = 98/241 (40%), Gaps = 15/241 (6%)

Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD-TQQRETEERIEISEKALAP 392
           G  T L  +P   I  SG L +++     VQ    +Y    T   ++            P
Sbjct: 373 GDRTPLPVDPRVNITPSGGLYIQN----VVQGDSGEYACSATNNIDSVHATAFIIVQALP 428

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           QF    QDR V EG+   F C   G P P + W     Q+  D  H  LV  SG   L I
Sbjct: 429 QFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH--LVLSSG--TLRI 484

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
           + V L D G   C A N  G       L V   +  V P F    S   V  G  V L  
Sbjct: 485 SGVALHDQGQYECQAVNIIGSQKVVAHLTV---QPRVTPVFASIPSDTTVEVGANVQLPC 541

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            + G P P ITW KDGV +  + +  I  +G  +  D+  A   DA  Y+C A+N  GS 
Sbjct: 542 SSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPA---DAGRYECVARNTIGSA 598

Query: 573 A 573
           +
Sbjct: 599 S 599



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 79/313 (25%), Positives = 123/313 (39%), Gaps = 41/313 (13%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+I  +P+++ +  G    F  +  GNP+P + W +N   L +      +   +  TL +
Sbjct: 241 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNEL-SMKTDSRLNLLDDGTLMI 299

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
           +NTQ++D G Y  +A+N  G + T      E     +    R  ++              
Sbjct: 300 QNTQETDQGIYQCMAKNVAGEVKTQ-----EVTLRYFGSPARPTFV-------------- 340

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
               + PQ  +V     VT       +C  TG P P ++W   DR      + ++ +  S
Sbjct: 341 ----IQPQNTEVLVGESVT------LECSATGHPPPRISWTRGDRTPL-PVDPRVNITPS 389

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
           G   L I NV   DSG   C A N   ++       +++      P+F        V EG
Sbjct: 390 G--GLYIQNVVQGDSGEYACSATNNI-DSVHATAFIIVQ----ALPQFTVTPQDRVVIEG 442

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           + V     A G P P I W K G  +  +   R H    + TL I      D   Y+C A
Sbjct: 443 QTVDFQCEAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 499

Query: 566 QNVAGSTATRARL 578
            N+ GS    A L
Sbjct: 500 VNIIGSQKVVAHL 512



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 73/321 (22%), Positives = 117/321 (36%), Gaps = 28/321 (8%)

Query: 48  MTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR 107
           M   V      Q +T    G P+ P F    +N     G +   E    G+P P +SWTR
Sbjct: 313 MAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR 372

Query: 108 -KKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGX 166
             + PL    + ++     T    L I+ +  GD GEY C+A N       + +I  +  
Sbjct: 373 GDRTPLPVDPRVNI-----TPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL 427

Query: 167 XXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTD--DFKVD 224
                            +TV+ +          +      +A+T G    S D     + 
Sbjct: 428 PQFTVTPQDRVVIE--GQTVDFQCEA-------KGNPPPVIAWTKGGSQLSVDRRHLVLS 478

Query: 225 TFEYRL----LREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEG 280
           +   R+    L +    E      +G   V     +   + PV     A  P ++ ++ G
Sbjct: 479 SGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPV----FASIPSDTTVEVG 534

Query: 281 ADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLA 340
           A+ Q      G P P +TW K+G ++  S K  I        L + +   +D+G Y  +A
Sbjct: 535 ANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHI---SPEGFLTINDVGPADAGRYECVA 591

Query: 341 ENPNGCIVTSGYLAVESPTES 361
            N  G    S  L+V  P  S
Sbjct: 592 RNTIGSASVSMVLSVNVPDVS 612



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 8/94 (8%)

Query: 2368 PEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRN--EKLIEDSSRI 2425
            PE +  +RP  T   Q+ D +  G T +F CR    G+P  ++ W RN  E  ++  SR+
Sbjct: 233  PEELNCERPRITSEPQDAD-VTSGNTVYFTCRA--EGNPKPEIIWLRNNNELSMKTDSRL 289

Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                D    ++ I + ++ D+G+Y C A N+ GE
Sbjct: 290  NLLDDG---TLMIQNTQETDQGIYQCMAKNVAGE 320



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 52/228 (22%), Positives = 86/228 (37%), Gaps = 22/228 (9%)

Query: 3075 TGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            TG     I W    +T +    R+    + G+ +  ++     DSG Y+C ATN      
Sbjct: 361  TGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVV---QGDSGEYACSATNNIDSVH 417

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
             +  +          P+FT   Q+   + +GQ+  F+C      +P   I W   G  + 
Sbjct: 418  ATAFIIVQ-----ALPQFTVTPQD-RVVIEGQTVDFQCEAK--GNPPPVIAWTKGGSQLS 469

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
               R   +S     +  +A    HD G+Y C+A N  G     A +    +      S+ 
Sbjct: 470  VDRRHLVLSSGTLRISGVAL---HDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIP 526

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAH 3301
             D+  ++       GA  Q P +   EP   IT  +D  ++ E    H
Sbjct: 527  SDTTVEV-------GANVQLPCSSQGEPEPAITWNKDGVQVTESGKFH 567



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 43/130 (33%), Positives = 58/130 (44%), Gaps = 12/130 (9%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA--TGS 3742
            IT E+     PR T E +D  DV  G  V+F CR E  G+P   I W  N    +  T S
Sbjct: 231  ITPEELNCERPRITSEPQD-ADVTSGNTVYFTCRAE--GNPKPEIIWLRNNNELSMKTDS 287

Query: 3743 RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT---TAKITCS-AKRDIVLESQ 3798
            R++ L+D     L I      D G Y C A N  G   T   T +   S A+   V++ Q
Sbjct: 288  RLNLLDDG---TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQ 344

Query: 3799 LPQGMSGEKI 3808
              + + GE +
Sbjct: 345  NTEVLVGESV 354



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 46/190 (24%), Positives = 73/190 (38%), Gaps = 12/190 (6%)

Query: 3040 PDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRT 3099
            P++     P  T+  +D  D++ G   ++       G+    I W  N   +      R 
Sbjct: 233  PEELNCERPRITSEPQD-ADVTSGNTVYFTCRA--EGNPKPEIIWLRNNNELSMKTDSR- 288

Query: 3100 VYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159
            +       L I  T+ TD G Y C A N  G+ + + ++         +P F    QN E
Sbjct: 289  LNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVK-TQEVTLRYFGSPARPTFVIQPQNTE 347

Query: 3160 GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ-PMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
             L  G+S   EC+      P  +I W    + P+    R+      G  + ++      D
Sbjct: 348  VLV-GESVTLECSA--TGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVV---QGD 401

Query: 3219 SGEYVCRAYN 3228
            SGEY C A N
Sbjct: 402  SGEYACSATN 411



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           PQF V  +    +EG  + F+   E  G+P   I W K G  +    R   +   G + +
Sbjct: 428 PQFTVTPQDRVVIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRHL-VLSSGTLRI 484

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             ++L+  D G+Y C+AV+  G  +  A L V PR T
Sbjct: 485 SGVALH--DQGQYECQAVNIIGSQKVVAHLTVQPRVT 519



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 11/123 (8%)

Query: 3544 TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL--L 3601
            +V T+TPE  +   P  T+ P D  ++  ++ +F CR     +    + W  N   L   
Sbjct: 227  SVATITPEELNCERPRITSEPQDADVTSGNTVYFTCR--AEGNPKPEIIWLRNNNELSMK 284

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA-TVSCKLQVKG---RQGIIL 3657
            T SR+  ++D G ++++     + D G+Y C A N  GE  T    L+  G   R   ++
Sbjct: 285  TDSRLNLLDD-GTLMIQ--NTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVI 341

Query: 3658 EPQ 3660
            +PQ
Sbjct: 342  QPQ 344



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 7/111 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+F   P+    VIEGQ V F+C  E   +    + W K G  +++  R   +       
Sbjct: 428  PQFTVTPQD-RVVIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG---T 481

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR-STTDIVRSTQNEAGLE 1553
            L I  +   D G Y C+AVN++G+ +V   LT +   T +  S  ++  +E
Sbjct: 482  LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVE 532



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 8/111 (7%)

Query: 3681 KREEITIED-EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR-PF 3738
            K +E+T+     P  P F ++   N +V  G  V  +C     G P  RI W    R P 
Sbjct: 322  KTQEVTLRYFGSPARPTFVIQ-PQNTEVLVGESVTLECSA--TGHPPPRISWTRGDRTPL 378

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
                RV+     G   L I  +   D+GEY C ATN   S   TA I   A
Sbjct: 379  PVDPRVNITPSGG---LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 426



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 6/92 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+FTV  +D + V EG  V F C  E  G+P   I W   G   +   R H +   G   
Sbjct: 428  PQFTVTPQDRV-VIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRR-HLVLSSG--T 481

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            L I  +   D G+Y C+A N  GS    A +T
Sbjct: 482  LRISGVALHDQGQYECQAVNIIGSQKVVAHLT 513



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 8/119 (6%)

Query: 2638 VQQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            VQ  P FT  +   D++V EGQ V  + Q E + +P   I W K G  L+   R      
Sbjct: 424  VQALPQFT--VTPQDRVVIEGQTV--DFQCEAKGNPPPVIAWTKGGSQLSVDRR-HLVLS 478

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGA 2755
             G  TL I+ +   D G Y C+A N++G     A + ++ R   +  S+  D+   +GA
Sbjct: 479  SG--TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGA 535



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 9/85 (10%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN--TIVN 4153
            +TPE++  E      P   S P    V  G    F CR  G+PKP ++WL N N  ++  
Sbjct: 231  ITPEELNCER-----PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKT 285

Query: 4154 GSRYKLTYDGMYHFDIPKTRQYDTG 4178
             SR  L  DG     I  T++ D G
Sbjct: 286  DSRLNLLDDGT--LMIQNTQETDQG 308



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/129 (22%), Positives = 56/129 (43%), Gaps = 4/129 (3%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + + K   GE   Q  T   R  G  + P    +P+N+++  G     +   +G+P PR+
Sbjct: 311 QCMAKNVAGEVKTQEVTL--RYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRI 368

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
           +W +  +  +  +    IT      L ++N  + DSG Y   A N    +  + ++ V++
Sbjct: 369 SWTRGDRTPLPVDPRVNITPSG--GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 426

Query: 358 PTESYVQDQ 366
             +  V  Q
Sbjct: 427 LPQFTVTPQ 435



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 5/95 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+FT TP D ++ E  +  F+C      +    + W   G  L    R   ++      L
Sbjct: 428  PQFTVTPQDRVVIEGQTVDFQCE--AKGNPPPVIAWTKGGSQLSVDRRHLVLSS---GTL 482

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             I GV   D G Y C+A N  G   V   L V+ R
Sbjct: 483  RISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR 517



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/92 (25%), Positives = 36/92 (39%), Gaps = 2/92 (2%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF 4167
            R  PVF S+P   TVE G   +  C   G P+P + W  +G  +    ++ ++ +G    
Sbjct: 517  RVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGF--L 574

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199
             I      D G+ E +             L V
Sbjct: 575  TINDVGPADAGRYECVARNTIGSASVSMVLSV 606



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           + P F  +  D  V  G   +  C   G P P +TW  +  Q+ +  + K  ++  G   
Sbjct: 518 VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTE--SGKFHISPEG--F 573

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           L I +V  +D+G   CVARN  G  +    L+V
Sbjct: 574 LTINDVGPADAGRYECVARNTIGSASVSMVLSV 606



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 6/93 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+F    +D++ I EG    F+   E  G+    + W K G  +    R     +     
Sbjct: 428  PQFTVTPQDRVVI-EGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG---T 481

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I  V +HD G Y C+A N IG     A+LT+
Sbjct: 482  LRISGVALHDQGQYECQAVNIIGSQKVVAHLTV 514



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 7/115 (6%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS-VTVGSRFKTYYD 1231
            S ++P FV    N   V  G+++ LEC     G P  R+ W    R+ + V  R      
Sbjct: 333  SPARPTFVIQPQNTE-VLVGESVTLEC--SATGHPPPRISWTRGDRTPLPVDPRVNITPS 389

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286
             G    +++     D+GEY   A N++ S H +A + V          Q+   IE
Sbjct: 390  GGLYIQNVVQG---DSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIE 441



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV   P+F    +   V E + V F+C  E K +P   I W + G  L    R+  V   
Sbjct: 423  IVQALPQFTVTPQDRVVIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRH-LVLSS 479

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911
            G  +L I  V   D G+Y C+AVN  G
Sbjct: 480  G--TLRISGVALHDQGQYECQAVNIIG 504



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            PVF   + +   V  G N+ L C  +  G+P   + W  +G  VT   +F    + GF+ 
Sbjct: 520  PVFAS-IPSDTTVEVGANVQLPCSSQ--GEPEPAITWNKDGVQVTESGKFHISPE-GFLT 575

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            ++ +    AD G Y   A N +GSA  S ++ V
Sbjct: 576  INDVGP--ADAGRYECVARNTIGSASVSMVLSV 606



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            PVF     D  V     A+ +      G+P+  + W ++GV +  S +     + G++ +
Sbjct: 520  PVFASIPSDTTV--EVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPE-GFLTI 576

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            N   V P D+G Y C A N +G A  S  L V
Sbjct: 577  ND--VGPADAGRYECVARNTIGSASVSMVLSV 606



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 6/103 (5%)

Query: 1706 VITQA-PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            +I QA P FT+  +D  V E Q   F+      G+P   + W + G  +    R   +  
Sbjct: 422  IIVQALPQFTVTPQDRVVIEGQTVDFQCEA--KGNPPPVIAWTKGGSQLSVDRRHLVLSS 479

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
                 L +  V   D G Y C+A+N +G     + L VQ + +
Sbjct: 480  G---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVT 519



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 7/95 (7%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG--VPIEASNRLTT 1761
            +E+  + P  T   +D  V      +F  R    G+PK  + WLRN   + ++  +RL  
Sbjct: 234  EELNCERPRITSEPQDADVTSGNTVYFTCRA--EGNPKPEIIWLRNNNELSMKTDSRLNL 291

Query: 1762 MHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            + D     L ++     D G Y C A N  GE  T
Sbjct: 292  LDDG---TLMIQNTQETDQGIYQCMAKNVAGEVKT 323



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 9/97 (9%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG--VTLTTGARLKSTFDF 2697
            + P  T+  +  D +  G  VY   + E    P  +I W +N   +++ T +RL +  D 
Sbjct: 239  ERPRITSEPQDAD-VTSGNTVYFTCRAEGNPKP--EIIWLRNNNELSMKTDSRL-NLLDD 294

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  TL I + +  D GIY C A N+ GE V T  + +
Sbjct: 295  G--TLMIQNTQETDQGIYQCMAKNVAGE-VKTQEVTL 328



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/104 (31%), Positives = 40/104 (38%), Gaps = 6/104 (5%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL-LPSGHRYRTVYDMGFVS 3888
            P F+ Q ++  V   E V  EC       P  RI W R  +  LP   R       G   
Sbjct: 337  PTFVIQPQNTEVLVGESVTLECSATGHPPP--RISWTRGDRTPLPVDPRVNITPSGG--- 391

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            L I  V   DSGEY C A N+       A I  + LP   +  Q
Sbjct: 392  LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQ 435



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 3/76 (3%)

Query: 79  KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
           ++A    G    F  +  GNP P + W R    L    K   R N    D +L+I+    
Sbjct: 248 QDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNEL--SMKTDSRLN-LLDDGTLMIQNTQE 304

Query: 139 GDEGEYTCTARNQYGE 154
            D+G Y C A+N  GE
Sbjct: 305 TDQGIYQCMAKNVAGE 320



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+ ++F C  E +  P  +I W  NN  L   T  +  +     +L I +T E D GIY 
Sbjct: 255  GNTVYFTCRAEGNPKP--EIIWLRNNNELSMKTDSR-LNLLDDGTLMIQNTQETDQGIYQ 311

Query: 2848 CKATNSKGSATT 2859
            C A N  G   T
Sbjct: 312  CMAKNVAGEVKT 323



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 9/113 (7%)

Query: 3147 QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP--MRHSTRIKTVSDF 3204
            ++PR T+  Q+ + +  G + +F C      +P  +I W  N     M+  +R+  + D 
Sbjct: 239  ERPRITSEPQDAD-VTSGNTVYFTCRAE--GNPKPEIIWLRNNNELSMKTDSRLNLLDDG 295

Query: 3205 GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR-ATINCYGKGGVYLESLQPDS 3256
                L I  TQ  D G Y C A N  GE  T+  T+  +G        +QP +
Sbjct: 296  ---TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQN 345



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 1322 TVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
            TVE G NV L C  Q  G+    + W  +G  +    +F  + E     L +  V P D+
Sbjct: 530  TVEVGANVQLPCSSQ--GEPEPAITWNKDGVQVTESGKFHISPEG---FLTINDVGPADA 584

Query: 1381 GVYTCQATNQLGEAVTSCALRV 1402
            G Y C A N +G A  S  L V
Sbjct: 585  GRYECVARNTIGSASVSMVLSV 606



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 6/96 (6%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGR-PVQQGHRFKTTYDFGYV 2035
            +P F    +N EV  G  V LE + T    P  R+ W    R P+    R   T   G  
Sbjct: 336  RPTFVIQPQNTEVLVGESVTLECSAT--GHPPPRISWTRGDRTPLPVDPRVNITPSGGLY 393

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
              +++     D+G Y C ATN +     T+ + V A
Sbjct: 394  IQNVVQG---DSGEYACSATNNIDSVHATAFIIVQA 426



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 7/96 (7%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV-LQSGHRYRTSNDFGFA 1902
            P F+ Q    T++  G+S   EC    +P P  R+ W    +  L    R   +   G  
Sbjct: 337  PTFVIQPQN-TEVLVGESVTLECSATGHPPP--RISWTRGDRTPLPVDPRVNITPSGG-- 391

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
             L I  V   DSGEY C A NN+    ++  + VQ+
Sbjct: 392  -LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 426



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 5/82 (6%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EGQ+  ++C  +  P P   + W   G  L    R+   +      L I  V   D G+Y
Sbjct: 441  EGQTVDFQCEAKGNPPPV--IAWTKGGSQLSVDRRHLVLSS---GTLRISGVALHDQGQY 495

Query: 1918 TCKAINNLGQAVSSIRLNVQSK 1939
             C+A+N +G       L VQ +
Sbjct: 496  ECQAVNIIGSQKVVAHLTVQPR 517



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G+    + W KDG  V  S +       G+  LTI  V   DAG Y C A N IG A+ S
Sbjct: 545  GEPEPAITWNKDGVQVTESGKFHISPE-GF--LTINDVGPADAGRYECVARNTIGSASVS 601

Query: 997  ANLTI 1001
              L++
Sbjct: 602  MVLSV 606



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/40 (40%), Positives = 17/40 (42%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT 4150
            P FV  P    V  GE     C  TGHP PR+ W     T
Sbjct: 337  PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRT 376



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 5/92 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F + PSD  +   ++    C      +    + W  +G  +    +   I+  GF  L
Sbjct: 520  PVFASIPSDTTVEVGANVQLPCS--SQGEPEPAITWNKDGVQVTESGKFH-ISPEGF--L 574

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I  V   DAG Y C A N  G A+VS  L V
Sbjct: 575  TINDVGPADAGRYECVARNTIGSASVSMVLSV 606



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 6/83 (7%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P+F  +   PS+      A+ +      G+P     W  +GV++    +F  + + GF+T
Sbjct: 520  PVFASI---PSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPE-GFLT 575

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
              IN V   DAG Y C A N  G
Sbjct: 576  --INDVGPADAGRYECVARNTIG 596



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 6/119 (5%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            + +P+  I W  +G  + +  +F ++ + GF+T++  DV   D+G Y C A N  G A  
Sbjct: 544  QGEPEPAITWNKDGVQVTESGKFHISPE-GFLTIN--DVGPADAGRYECVARNTIGSASV 600

Query: 2998 SSTVYCTSKDNLIERTQHP-KGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFK 3055
            S  +     D  + R   P   T  +E I  ++ ++        D     P +   +F+
Sbjct: 601  SMVLSVNVPD--VSRNGDPFVATSIVEAIATVDRAINSTRTHLFDSRPRSPNDLLALFR 657



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 8/91 (8%)

Query: 3695 PRFT---VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG 3751
            PR T     I  +  V  G  V   C  +  G+P   I W  +G       + H ++  G
Sbjct: 516  PRVTPVFASIPSDTTVEVGANVQLPCSSQ--GEPEPAITWNKDGVQVTESGKFH-ISPEG 572

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            F  L I+ +   DAG Y C A N  GSA+ +
Sbjct: 573  F--LTINDVGPADAGRYECVARNTIGSASVS 601


>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated antigen
            MG50 protein.
          Length = 1496

 Score =  124 bits (298), Expect = 1e-26
 Identities = 106/401 (26%), Positives = 159/401 (39%), Gaps = 36/401 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P  T + Q   V       F    +G P P I W R N  +    D +++     + L+I
Sbjct: 263  PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGT-LMI 321

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            +     D  ++  +A+N  G  K       +E   +  G    P+F +  QN  V  G+ 
Sbjct: 322  QNTQETDQGIYQCMAKNVAGEVK------TQEVTLRYFGSPARPTFVIQPQNTEVLVGES 375

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQP-DIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
            V L+   TG  P  + W +  +   P D R  I    G Y   +++    DSG+Y C A 
Sbjct: 376  VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQG---DSGEYACSAT 432

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N+       A  +V                 A P+     +D++V EGQ ++F C+  G 
Sbjct: 433  NNIDSVHATAFIIVQ----------------ALPQFTVTPQDRVVIEGQTVDFQCEAKGN 476

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P P + W KG   +   +   +  +    TLRIS     D+G Y+C A N  G   V A 
Sbjct: 477  PPPVIAWTKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAH 533

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            L V QP +   + A  P  D  V  G   Q       + +P I W ++G  + E+  F +
Sbjct: 534  LTV-QP-RVTPVFASIP-SDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHI 590

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              EG    L I +    D G + C A    G    S  L V
Sbjct: 591  SPEG---FLTINDVGPADAGRYECVARNTIGSASVSMVLSV 628



 Score =  103 bits (247), Expect = 2e-20
 Identities = 94/346 (27%), Positives = 140/346 (40%), Gaps = 35/346 (10%)

Query: 4376 KEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFD 4435
            +E  + I       +  + +TQE  +     P++P  F  + Q   V   E    E    
Sbjct: 325  QETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPT-FVIQPQNTEVLVGESVTLECSAT 383

Query: 4436 GEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            G P P I W R +  P+   P   I   +    L I+ V   DS  +A  A N   +   
Sbjct: 384  GHPPPRISWTRGDRTPLPVDPRVNI---TPSGGLYIQNVVQGDSGEYACSATNNIDSVHA 440

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            +A ++V+            P FT+T Q+  V  GQ V    +  G  P  + W K G ++
Sbjct: 441  TAFIIVQAL----------PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQL 490

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
              D R+ +L      TL I      D G+YEC A+N  G  +  A   V       +P+ 
Sbjct: 491  SVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTV-------QPRV 540

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
                A+ P        D  V  G  ++  C   G+P P + W K    +  S  F +S  
Sbjct: 541  TPVFASIP-------SDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHIS-- 591

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
              E  L I++  P D G Y+CVA N+ G  +V+  L V  PD + N
Sbjct: 592  -PEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRN 636



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 77/301 (25%), Positives = 124/301 (41%), Gaps = 25/301 (8%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL 4572
            P  T   Q+ +VTSG  V    +  G    ++ WL+N  ++     +++ L +DG  TL+
Sbjct: 263  PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--TLM 320

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            I      D G Y+C+A N AGE +           T++       +   P  +I+P   +
Sbjct: 321  IQNTQETDQGIYQCMAKNVAGEVK-----------TQEVTLRYFGSPARPTFVIQPQNTE 369

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            ++  G+++   C   G P P + W +GD+   P              L I      D G+
Sbjct: 370  VLV-GESVTLECSATGHPPPRISWTRGDR--TPLPVDPRVNITPSGGLYIQNVVQGDSGE 426

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
            Y C A N+   V   A + V    QA     +TP +D VV EGQ   F+ +      P I
Sbjct: 427  YACSATNNIDSVHATAFIIV----QALPQFTVTP-QDRVVIEGQTVDFQCEAKGNPPPVI 481

Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             W + G+ +       ++  G    L I      D G + C+A    G  +  A L V+ 
Sbjct: 482  AWTKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQP 538

Query: 4813 K 4813
            +
Sbjct: 539  R 539



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 57/177 (32%), Positives = 82/177 (46%), Gaps = 7/177 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+     QD DVT G    F CR  G P PE+ W  N+ ++    + ++ + + G   LM
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--TLM 320

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I N   +D G+  C+A+N +GE   Q  + +        P FV +     V  GE V L 
Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQ-EVTLRYFGSPARPTFVIQPQNTEVLVGESVTLE 379

Query: 512 ARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
             A G P PRI+W + D  P+  +P + I   GG   L I      D+  Y C+A N
Sbjct: 380 CSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG---LYIQNVVQGDSGEYACSATN 433



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 76/241 (31%), Positives = 98/241 (40%), Gaps = 15/241 (6%)

Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD-TQQRETEERIEISEKALAP 392
           G  T L  +P   I  SG L +++     VQ    +Y    T   ++            P
Sbjct: 395 GDRTPLPVDPRVNITPSGGLYIQN----VVQGDSGEYACSATNNIDSVHATAFIIVQALP 450

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           QF    QDR V EG+   F C   G P P + W     Q+  D  H  LV  SG   L I
Sbjct: 451 QFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH--LVLSSG--TLRI 506

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
           + V L D G   C A N  G       L V   +  V P F    S   V  G  V L  
Sbjct: 507 SGVALHDQGQYECQAVNIIGSQKVVAHLTV---QPRVTPVFASIPSDTTVEVGANVQLPC 563

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            + G P P ITW KDGV +  + +  I  +G  +  D+  A   DA  Y+C A+N  GS 
Sbjct: 564 SSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPA---DAGRYECVARNTIGSA 620

Query: 573 A 573
           +
Sbjct: 621 S 621



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 79/313 (25%), Positives = 123/313 (39%), Gaps = 41/313 (13%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+I  +P+++ +  G    F  +  GNP+P + W +N   L +      +   +  TL +
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNEL-SMKTDSRLNLLDDGTLMI 321

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
           +NTQ++D G Y  +A+N  G + T      E     +    R  ++              
Sbjct: 322 QNTQETDQGIYQCMAKNVAGEVKTQ-----EVTLRYFGSPARPTFV-------------- 362

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
               + PQ  +V     VT       +C  TG P P ++W   DR      + ++ +  S
Sbjct: 363 ----IQPQNTEVLVGESVT------LECSATGHPPPRISWTRGDRTPL-PVDPRVNITPS 411

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
           G   L I NV   DSG   C A N   ++       +++      P+F        V EG
Sbjct: 412 G--GLYIQNVVQGDSGEYACSATNNI-DSVHATAFIIVQ----ALPQFTVTPQDRVVIEG 464

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           + V     A G P P I W K G  +  +   R H    + TL I      D   Y+C A
Sbjct: 465 QTVDFQCEAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 521

Query: 566 QNVAGSTATRARL 578
            N+ GS    A L
Sbjct: 522 VNIIGSQKVVAHL 534



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 73/321 (22%), Positives = 117/321 (36%), Gaps = 28/321 (8%)

Query: 48  MTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR 107
           M   V      Q +T    G P+ P F    +N     G +   E    G+P P +SWTR
Sbjct: 335 MAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR 394

Query: 108 -KKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGX 166
             + PL    + ++     T    L I+ +  GD GEY C+A N       + +I  +  
Sbjct: 395 GDRTPLPVDPRVNI-----TPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL 449

Query: 167 XXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTD--DFKVD 224
                            +TV+ +          +      +A+T G    S D     + 
Sbjct: 450 PQFTVTPQDRVVIE--GQTVDFQCEA-------KGNPPPVIAWTKGGSQLSVDRRHLVLS 500

Query: 225 TFEYRL----LREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEG 280
           +   R+    L +    E      +G   V     +   + PV     A  P ++ ++ G
Sbjct: 501 SGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPV----FASIPSDTTVEVG 556

Query: 281 ADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLA 340
           A+ Q      G P P +TW K+G ++  S K  I        L + +   +D+G Y  +A
Sbjct: 557 ANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHI---SPEGFLTINDVGPADAGRYECVA 613

Query: 341 ENPNGCIVTSGYLAVESPTES 361
            N  G    S  L+V  P  S
Sbjct: 614 RNTIGSASVSMVLSVNVPDVS 634



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 8/94 (8%)

Query: 2368 PEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRN--EKLIEDSSRI 2425
            PE +  +RP  T   Q+ D +  G T +F CR    G+P  ++ W RN  E  ++  SR+
Sbjct: 255  PEELNCERPRITSEPQDAD-VTSGNTVYFTCRA--EGNPKPEIIWLRNNNELSMKTDSRL 311

Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                D    ++ I + ++ D+G+Y C A N+ GE
Sbjct: 312  NLLDDG---TLMIQNTQETDQGIYQCMAKNVAGE 342



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 52/228 (22%), Positives = 86/228 (37%), Gaps = 22/228 (9%)

Query: 3075 TGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            TG     I W    +T +    R+    + G+ +  ++     DSG Y+C ATN      
Sbjct: 383  TGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVV---QGDSGEYACSATNNIDSVH 439

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
             +  +          P+FT   Q+   + +GQ+  F+C      +P   I W   G  + 
Sbjct: 440  ATAFIIVQ-----ALPQFTVTPQD-RVVIEGQTVDFQCEAK--GNPPPVIAWTKGGSQLS 491

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
               R   +S     +  +A    HD G+Y C+A N  G     A +    +      S+ 
Sbjct: 492  VDRRHLVLSSGTLRISGVAL---HDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIP 548

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAH 3301
             D+  ++       GA  Q P +   EP   IT  +D  ++ E    H
Sbjct: 549  SDTTVEV-------GANVQLPCSSQGEPEPAITWNKDGVQVTESGKFH 589



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 43/130 (33%), Positives = 58/130 (44%), Gaps = 12/130 (9%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA--TGS 3742
            IT E+     PR T E +D  DV  G  V+F CR E  G+P   I W  N    +  T S
Sbjct: 253  ITPEELNCERPRITSEPQD-ADVTSGNTVYFTCRAE--GNPKPEIIWLRNNNELSMKTDS 309

Query: 3743 RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT---TAKITCS-AKRDIVLESQ 3798
            R++ L+D     L I      D G Y C A N  G   T   T +   S A+   V++ Q
Sbjct: 310  RLNLLDDG---TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQ 366

Query: 3799 LPQGMSGEKI 3808
              + + GE +
Sbjct: 367  NTEVLVGESV 376



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 46/190 (24%), Positives = 73/190 (38%), Gaps = 12/190 (6%)

Query: 3040 PDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRT 3099
            P++     P  T+  +D  D++ G   ++       G+    I W  N   +      R 
Sbjct: 255  PEELNCERPRITSEPQD-ADVTSGNTVYFTCRA--EGNPKPEIIWLRNNNELSMKTDSR- 310

Query: 3100 VYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159
            +       L I  T+ TD G Y C A N  G+ + + ++         +P F    QN E
Sbjct: 311  LNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVK-TQEVTLRYFGSPARPTFVIQPQNTE 369

Query: 3160 GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ-PMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
             L  G+S   EC+      P  +I W    + P+    R+      G  + ++      D
Sbjct: 370  VLV-GESVTLECSA--TGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVV---QGD 423

Query: 3219 SGEYVCRAYN 3228
            SGEY C A N
Sbjct: 424  SGEYACSATN 433



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           PQF V  +    +EG  + F+   E  G+P   I W K G  +    R   +   G + +
Sbjct: 450 PQFTVTPQDRVVIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRHL-VLSSGTLRI 506

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             ++L+  D G+Y C+AV+  G  +  A L V PR T
Sbjct: 507 SGVALH--DQGQYECQAVNIIGSQKVVAHLTVQPRVT 541



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 11/123 (8%)

Query: 3544 TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL--L 3601
            +V T+TPE  +   P  T+ P D  ++  ++ +F CR     +    + W  N   L   
Sbjct: 249  SVATITPEELNCERPRITSEPQDADVTSGNTVYFTCR--AEGNPKPEIIWLRNNNELSMK 306

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA-TVSCKLQVKG---RQGIIL 3657
            T SR+  ++D G ++++     + D G+Y C A N  GE  T    L+  G   R   ++
Sbjct: 307  TDSRLNLLDD-GTLMIQ--NTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVI 363

Query: 3658 EPQ 3660
            +PQ
Sbjct: 364  QPQ 366



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 7/111 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+F   P+    VIEGQ V F+C  E   +    + W K G  +++  R   +       
Sbjct: 450  PQFTVTPQD-RVVIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG---T 503

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR-STTDIVRSTQNEAGLE 1553
            L I  +   D G Y C+AVN++G+ +V   LT +   T +  S  ++  +E
Sbjct: 504  LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVE 554



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 8/111 (7%)

Query: 3681 KREEITIED-EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR-PF 3738
            K +E+T+     P  P F ++   N +V  G  V  +C     G P  RI W    R P 
Sbjct: 344  KTQEVTLRYFGSPARPTFVIQ-PQNTEVLVGESVTLECSA--TGHPPPRISWTRGDRTPL 400

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
                RV+     G   L I  +   D+GEY C ATN   S   TA I   A
Sbjct: 401  PVDPRVNITPSGG---LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 448



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 6/92 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+FTV  +D + V EG  V F C  E  G+P   I W   G   +   R H +   G   
Sbjct: 450  PQFTVTPQDRV-VIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRR-HLVLSSG--T 503

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            L I  +   D G+Y C+A N  GS    A +T
Sbjct: 504  LRISGVALHDQGQYECQAVNIIGSQKVVAHLT 535



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 8/119 (6%)

Query: 2638 VQQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            VQ  P FT  +   D++V EGQ V  + Q E + +P   I W K G  L+   R      
Sbjct: 446  VQALPQFT--VTPQDRVVIEGQTV--DFQCEAKGNPPPVIAWTKGGSQLSVDRR-HLVLS 500

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGA 2755
             G  TL I+ +   D G Y C+A N++G     A + ++ R   +  S+  D+   +GA
Sbjct: 501  SG--TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGA 557



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 9/85 (10%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN--TIVN 4153
            +TPE++  E      P   S P    V  G    F CR  G+PKP ++WL N N  ++  
Sbjct: 253  ITPEELNCER-----PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKT 307

Query: 4154 GSRYKLTYDGMYHFDIPKTRQYDTG 4178
             SR  L  DG     I  T++ D G
Sbjct: 308  DSRLNLLDDGT--LMIQNTQETDQG 330



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/129 (22%), Positives = 56/129 (43%), Gaps = 4/129 (3%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           + + K   GE   Q  T   R  G  + P    +P+N+++  G     +   +G+P PR+
Sbjct: 333 QCMAKNVAGEVKTQEVTL--RYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRI 390

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
           +W +  +  +  +    IT      L ++N  + DSG Y   A N    +  + ++ V++
Sbjct: 391 SWTRGDRTPLPVDPRVNITPSG--GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 448

Query: 358 PTESYVQDQ 366
             +  V  Q
Sbjct: 449 LPQFTVTPQ 457



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 5/95 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+FT TP D ++ E  +  F+C      +    + W   G  L    R   ++      L
Sbjct: 450  PQFTVTPQDRVVIEGQTVDFQCE--AKGNPPPVIAWTKGGSQLSVDRRHLVLSS---GTL 504

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             I GV   D G Y C+A N  G   V   L V+ R
Sbjct: 505  RISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR 539



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/92 (25%), Positives = 36/92 (39%), Gaps = 2/92 (2%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF 4167
            R  PVF S+P   TVE G   +  C   G P+P + W  +G  +    ++ ++ +G    
Sbjct: 539  RVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGF--L 596

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199
             I      D G+ E +             L V
Sbjct: 597  TINDVGPADAGRYECVARNTIGSASVSMVLSV 628



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           + P F  +  D  V  G   +  C   G P P +TW  +  Q+ +  + K  ++  G   
Sbjct: 540 VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTE--SGKFHISPEG--F 595

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           L I +V  +D+G   CVARN  G  +    L+V
Sbjct: 596 LTINDVGPADAGRYECVARNTIGSASVSMVLSV 628



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 6/93 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+F    +D++ I EG    F+   E  G+    + W K G  +    R     +     
Sbjct: 450  PQFTVTPQDRVVI-EGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG---T 503

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I  V +HD G Y C+A N IG     A+LT+
Sbjct: 504  LRISGVALHDQGQYECQAVNIIGSQKVVAHLTV 536



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 7/115 (6%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS-VTVGSRFKTYYD 1231
            S ++P FV    N   V  G+++ LEC     G P  R+ W    R+ + V  R      
Sbjct: 355  SPARPTFVIQPQNTE-VLVGESVTLEC--SATGHPPPRISWTRGDRTPLPVDPRVNITPS 411

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286
             G    +++     D+GEY   A N++ S H +A + V          Q+   IE
Sbjct: 412  GGLYIQNVVQG---DSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIE 463



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV   P+F    +   V E + V F+C  E K +P   I W + G  L    R+  V   
Sbjct: 445  IVQALPQFTVTPQDRVVIEGQTVDFQC--EAKGNPPPVIAWTKGGSQLSVDRRH-LVLSS 501

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911
            G  +L I  V   D G+Y C+AVN  G
Sbjct: 502  G--TLRISGVALHDQGQYECQAVNIIG 526



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            PVF   + +   V  G N+ L C  +  G+P   + W  +G  VT   +F    + GF+ 
Sbjct: 542  PVFAS-IPSDTTVEVGANVQLPCSSQ--GEPEPAITWNKDGVQVTESGKFHISPE-GFLT 597

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            ++ +    AD G Y   A N +GSA  S ++ V
Sbjct: 598  INDVGP--ADAGRYECVARNTIGSASVSMVLSV 628



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            PVF     D  V     A+ +      G+P+  + W ++GV +  S +     + G++ +
Sbjct: 542  PVFASIPSDTTV--EVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPE-GFLTI 598

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            N   V P D+G Y C A N +G A  S  L V
Sbjct: 599  ND--VGPADAGRYECVARNTIGSASVSMVLSV 628



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 6/103 (5%)

Query: 1706 VITQA-PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            +I QA P FT+  +D  V E Q   F+      G+P   + W + G  +    R   +  
Sbjct: 444  IIVQALPQFTVTPQDRVVIEGQTVDFQCEA--KGNPPPVIAWTKGGSQLSVDRRHLVLSS 501

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
                 L +  V   D G Y C+A+N +G     + L VQ + +
Sbjct: 502  G---TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVT 541



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 7/95 (7%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG--VPIEASNRLTT 1761
            +E+  + P  T   +D  V      +F  R    G+PK  + WLRN   + ++  +RL  
Sbjct: 256  EELNCERPRITSEPQDADVTSGNTVYFTCRA--EGNPKPEIIWLRNNNELSMKTDSRLNL 313

Query: 1762 MHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            + D     L ++     D G Y C A N  GE  T
Sbjct: 314  LDDG---TLMIQNTQETDQGIYQCMAKNVAGEVKT 345



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 9/97 (9%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG--VTLTTGARLKSTFDF 2697
            + P  T+  +  D +  G  VY   + E    P  +I W +N   +++ T +RL +  D 
Sbjct: 261  ERPRITSEPQDAD-VTSGNTVYFTCRAEGNPKP--EIIWLRNNNELSMKTDSRL-NLLDD 316

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  TL I + +  D GIY C A N+ GE V T  + +
Sbjct: 317  G--TLMIQNTQETDQGIYQCMAKNVAGE-VKTQEVTL 350



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/104 (31%), Positives = 40/104 (38%), Gaps = 6/104 (5%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL-LPSGHRYRTVYDMGFVS 3888
            P F+ Q ++  V   E V  EC       P  RI W R  +  LP   R       G   
Sbjct: 359  PTFVIQPQNTEVLVGESVTLECSATGHPPP--RISWTRGDRTPLPVDPRVNITPSGG--- 413

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            L I  V   DSGEY C A N+       A I  + LP   +  Q
Sbjct: 414  LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQ 457



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 3/76 (3%)

Query: 79  KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
           ++A    G    F  +  GNP P + W R    L    K   R N    D +L+I+    
Sbjct: 270 QDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNEL--SMKTDSRLN-LLDDGTLMIQNTQE 326

Query: 139 GDEGEYTCTARNQYGE 154
            D+G Y C A+N  GE
Sbjct: 327 TDQGIYQCMAKNVAGE 342



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+ ++F C  E +  P  +I W  NN  L   T  +  +     +L I +T E D GIY 
Sbjct: 277  GNTVYFTCRAEGNPKP--EIIWLRNNNELSMKTDSR-LNLLDDGTLMIQNTQETDQGIYQ 333

Query: 2848 CKATNSKGSATT 2859
            C A N  G   T
Sbjct: 334  CMAKNVAGEVKT 345



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 9/113 (7%)

Query: 3147 QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP--MRHSTRIKTVSDF 3204
            ++PR T+  Q+ + +  G + +F C      +P  +I W  N     M+  +R+  + D 
Sbjct: 261  ERPRITSEPQDAD-VTSGNTVYFTCRAE--GNPKPEIIWLRNNNELSMKTDSRLNLLDDG 317

Query: 3205 GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR-ATINCYGKGGVYLESLQPDS 3256
                L I  TQ  D G Y C A N  GE  T+  T+  +G        +QP +
Sbjct: 318  ---TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQN 367



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 1322 TVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
            TVE G NV L C  Q  G+    + W  +G  +    +F  + E     L +  V P D+
Sbjct: 552  TVEVGANVQLPCSSQ--GEPEPAITWNKDGVQVTESGKFHISPEG---FLTINDVGPADA 606

Query: 1381 GVYTCQATNQLGEAVTSCALRV 1402
            G Y C A N +G A  S  L V
Sbjct: 607  GRYECVARNTIGSASVSMVLSV 628



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 6/96 (6%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGR-PVQQGHRFKTTYDFGYV 2035
            +P F    +N EV  G  V LE + T    P  R+ W    R P+    R   T   G  
Sbjct: 358  RPTFVIQPQNTEVLVGESVTLECSAT--GHPPPRISWTRGDRTPLPVDPRVNITPSGGLY 415

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
              +++     D+G Y C ATN +     T+ + V A
Sbjct: 416  IQNVVQG---DSGEYACSATNNIDSVHATAFIIVQA 448



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 7/96 (7%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV-LQSGHRYRTSNDFGFA 1902
            P F+ Q    T++  G+S   EC    +P P  R+ W    +  L    R   +   G  
Sbjct: 359  PTFVIQPQN-TEVLVGESVTLECSATGHPPP--RISWTRGDRTPLPVDPRVNITPSGG-- 413

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
             L I  V   DSGEY C A NN+    ++  + VQ+
Sbjct: 414  -LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 448



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 5/82 (6%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EGQ+  ++C  +  P P   + W   G  L    R+   +      L I  V   D G+Y
Sbjct: 463  EGQTVDFQCEAKGNPPPV--IAWTKGGSQLSVDRRHLVLSS---GTLRISGVALHDQGQY 517

Query: 1918 TCKAINNLGQAVSSIRLNVQSK 1939
             C+A+N +G       L VQ +
Sbjct: 518  ECQAVNIIGSQKVVAHLTVQPR 539



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G+    + W KDG  V  S +       G+  LTI  V   DAG Y C A N IG A+ S
Sbjct: 567  GEPEPAITWNKDGVQVTESGKFHISPE-GF--LTINDVGPADAGRYECVARNTIGSASVS 623

Query: 997  ANLTI 1001
              L++
Sbjct: 624  MVLSV 628



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/40 (40%), Positives = 17/40 (42%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT 4150
            P FV  P    V  GE     C  TGHP PR+ W     T
Sbjct: 359  PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRT 398



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 5/92 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F + PSD  +   ++    C      +    + W  +G  +    +   I+  GF  L
Sbjct: 542  PVFASIPSDTTVEVGANVQLPCS--SQGEPEPAITWNKDGVQVTESGKFH-ISPEGF--L 596

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I  V   DAG Y C A N  G A+VS  L V
Sbjct: 597  TINDVGPADAGRYECVARNTIGSASVSMVLSV 628



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 6/83 (7%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P+F  +   PS+      A+ +      G+P     W  +GV++    +F  + + GF+T
Sbjct: 542  PVFASI---PSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPE-GFLT 597

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
              IN V   DAG Y C A N  G
Sbjct: 598  --INDVGPADAGRYECVARNTIG 618



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 6/119 (5%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            + +P+  I W  +G  + +  +F ++ + GF+T++  DV   D+G Y C A N  G A  
Sbjct: 566  QGEPEPAITWNKDGVQVTESGKFHISPE-GFLTIN--DVGPADAGRYECVARNTIGSASV 622

Query: 2998 SSTVYCTSKDNLIERTQHP-KGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFK 3055
            S  +     D  + R   P   T  +E I  ++ ++        D     P +   +F+
Sbjct: 623  SMVLSVNVPD--VSRNGDPFVATSIVEAIATVDRAINSTRTHLFDSRPRSPNDLLALFR 679



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 8/91 (8%)

Query: 3695 PRFT---VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG 3751
            PR T     I  +  V  G  V   C  +  G+P   I W  +G       + H ++  G
Sbjct: 538  PRVTPVFASIPSDTTVEVGANVQLPCSSQ--GEPEPAITWNKDGVQVTESGKFH-ISPEG 594

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            F  L I+ +   DAG Y C A N  GSA+ +
Sbjct: 595  F--LTINDVGPADAGRYECVARNTIGSASVS 623


>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
          Length = 1378

 Score =  121 bits (292), Expect = 6e-26
 Identities = 110/414 (26%), Positives = 171/414 (41%), Gaps = 48/414 (11%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI---KNSPDFQIHTFSTKS 4466
            PP   +      V + E      + +G P P I+WY++   +   K+ P        + S
Sbjct: 30   PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 89

Query: 4467 ILIIRQVFVE----DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            +  +R V       D   +  VA N  G A  S N  +E         ++   F     +
Sbjct: 90   LFFLRIVHGRRSKPDEGSYVCVARNYLGEA-VSRNASLEV-------ALLRDDFRQNPTD 141

Query: 4523 VNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            V V +G+   L+ +     P   +YW K+  KV+ D + + +   G   L+I      D+
Sbjct: 142  VVVAAGEPAILECQPPRGHPEPTIYWKKD--KVRIDDKEERISIRGG-KLMISNTRKSDA 198

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G Y CV  N  GE              +D    +      P  +  P+ +++V E +A+E
Sbjct: 199  GMYTCVGTNMVGE--------------RDSDPAELTVFERPTFLRRPI-NQVVLEEEAVE 243

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            F C++ G P PTV+W K D  +   +Y       D+YTLRI +    DEG Y C+A N  
Sbjct: 244  FRCQVQGDPQPTVRWKKDDADLPRGRY----DIKDDYTLRIKKTMSTDEGTYMCIAENRV 299

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-- 4759
            G++  +A L V  P Q    P     RD +V +G+   F  +     +P + W +EG+  
Sbjct: 300  GKMEASATLTVRAPPQFVVRP-----RDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQN 354

Query: 4760 -LIPETPD--FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L P  P              L I N    D G + C+A T AG +   A+L V
Sbjct: 355  LLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 408



 Score =  105 bits (252), Expect = 4e-21
 Identities = 110/383 (28%), Positives = 157/383 (40%), Gaps = 44/383 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I +  + +I     K  L+I      D+ ++  V  N  G     
Sbjct: 159  GHPEPTIYWKKDKVRIDDKEE-RISIRGGK--LMISNTRKSDAGMYTCVGTNMVGERDSD 215

Query: 4496 -ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
             A L V E+          P+F     N  V   + V    +V G     V W K+   +
Sbjct: 216  PAELTVFER----------PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL 265

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R  I ++   YTL I +    D G Y C+A N  G+    A               
Sbjct: 266  -PRGRYDIKDD---YTLRIKKTMSTDEGTYMCIAENRVGKMEASA--------------- 306

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYFQM- 4671
             T    APP+ +   +D+IVA+G+ + F C+  G P P V W K     L+ P++  Q  
Sbjct: 307  -TLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPN 365

Query: 4672 SRTADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ--PDQADNLPALTPL 4727
            SR +   T  L I+     D G Y C A   AG +   A+L+VT    D+   +    P 
Sbjct: 366  SRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPA 425

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
               +  +G  A  K + T    P I WL+EG   P       I E     L I N    D
Sbjct: 426  NQTLAVDGT-ALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE--QGTLQIKNLRISD 482

Query: 4788 TGTFTCRATTAAGQVETSAKLVV 4810
            TGT+TC AT+++G+   SA L V
Sbjct: 483  TGTYTCVATSSSGETSWSAVLDV 505



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 87/350 (24%), Positives = 140/350 (40%), Gaps = 38/350 (10%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F ++     V E E   F  +  G+P P ++W +++  +        +       L I
Sbjct: 225  PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGR----YDIKDDYTLRI 280

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            ++    D   +  +AENR G  + SA L V            PP F +  ++  V  G+ 
Sbjct: 281  KKTMSTDEGTYMCIAENRVGKMEASATLTVR----------APPQFVVRPRDQIVAQGRT 330

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKV-----QPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            V    +  G     V+W K G +      QP   N       T  L I      D+G Y 
Sbjct: 331  VTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI 390

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLKDKIVAEGQAIEFSC 4644
            C A+  AG     A+  V+   T D+P         PP I++ P    +  +G A+   C
Sbjct: 391  CQALTVAGSILAKAQLEVTDVLT-DRP---------PPIILQGPANQTLAVDGTAL-LKC 439

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            K  G PLP + W K +    P +    +   ++ TL+I      D G Y CVA +S+G  
Sbjct: 440  KATGDPLPVISWLK-EGFTFPGRD-PRATIQEQGTLQIKNLRISDTGTYTCVATSSSGET 497

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
            + +A L VT+         ++   D+    G P++ +    +K   T+ W
Sbjct: 498  SWSAVLDVTESG-----ATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW 542



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 83/309 (26%), Positives = 129/309 (41%), Gaps = 35/309 (11%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-----PDIRNKILEEDG 4567
            PP       +V V+ G+   L+ K  G     + W K+G++V+     P     +L    
Sbjct: 30   PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 89

Query: 4568 TYTLLILEA--YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             + L I+       D G Y CVA N  GEA       VS  A+ +    +      P ++
Sbjct: 90   LFFLRIVHGRRSKPDEGSYVCVARNYLGEA-------VSRNASLEVALLRDDFRQNPTDV 142

Query: 4626 IEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
                   +VA G+     C+   G P PT+ W K DK+    K  ++S    +  L IS 
Sbjct: 143  -------VVAAGEPAILECQPPRGHPEPTIYW-KKDKVRIDDKEERISIRGGK--LMISN 192

Query: 4685 AFPEDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                D G Y CV  N  G R +  A+L V +       P      + VV E +  +F+ Q
Sbjct: 193  TRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPI-----NQVVLEEEAVEFRCQ 247

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            +    +PT++W ++ A +P           ++  L I  T   D GT+ C A    G++E
Sbjct: 248  VQGDPQPTVRWKKDDADLPR----GRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKME 303

Query: 4804 TSAKLVVKS 4812
             SA L V++
Sbjct: 304  ASATLTVRA 312



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 81/317 (25%), Positives = 125/317 (39%), Gaps = 41/317 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+I + P +  + +G       +  G P P + W+K+G+R+                  
Sbjct: 30  PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERV------------------ 71

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-SYVQDQRSQYITDTQQRETEERI 383
              T K D   + +L  + +   +   +     P E SYV   R+ Y+ +   R     +
Sbjct: 72  --ETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARN-YLGEAVSRNASLEV 128

Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILV 442
            +    L   F +   D  V  G+    +C+   G P P + W   D+   DD   +I +
Sbjct: 129 AL----LRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWK-KDKVRIDDKEERISI 183

Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGE-TAFQCRLNVIEKEQVVAPKFVERFSTLN 501
                  LMI+N   SD+G+ TCV  N  GE  +    L V E+     P F+ R     
Sbjct: 184 RGG---KLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFER-----PTFLRRPINQV 235

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V E E V    +  G P P + W+KD    +P     I  D    TL I +  ++D   Y
Sbjct: 236 VLEEEAVEFRCQVQGDPQPTVRWKKDDAD-LPRGRYDIKDD---YTLRIKKTMSTDEGTY 291

Query: 562 QCTAQNVAGSTATRARL 578
            C A+N  G     A L
Sbjct: 292 MCIAENRVGKMEASATL 308



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 13/193 (6%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR----DDYNHKI 440
           + ++   P+ V+   D  V++G+ T  +C+  GRP P + W+ +  ++     D  +H++
Sbjct: 24  LRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRM 83

Query: 441 LVNESGNHALMITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498
           L+       L I +   S  D G   CVARN  GE   +   N   +  ++   F +  +
Sbjct: 84  LLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR---NASLEVALLRDDFRQNPT 140

Query: 499 TLNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            + V  GEP +L  +   G P P I W+KD V  I + E RI   GG   L I   + SD
Sbjct: 141 DVVVAAGEPAILECQPPRGHPEPTIYWKKDKVR-IDDKEERISIRGG--KLMISNTRKSD 197

Query: 558 AAWYQCTAQNVAG 570
           A  Y C   N+ G
Sbjct: 198 AGMYTCVGTNMVG 210



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 96/404 (23%), Positives = 163/404 (40%), Gaps = 51/404 (12%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P + W + K   V  +    R + + G   L+I      D G YTC   N  GE 
Sbjct: 158 RGHPEPTIYWKKDK---VRIDDKEERISIRGG--KLMISNTRKSDAGMYTCVGTNMVGE- 211

Query: 156 ICSVYIQPEGXXXXXXXXXXXXXYRHVSETV-EHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                 +                 R +++ V E +A   +       + T +    +   
Sbjct: 212 ------RDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL 265

Query: 215 HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
                D K D +  R+ + +S  E  T   + E+ V    E   +L   +PP+   +PR+
Sbjct: 266 PRGRYDIK-DDYTLRIKKTMSTDEG-TYMCIAENRVG-KMEASATLTVRAPPQFVVRPRD 322

Query: 275 SKLQEGADAQFQVQLSGNPRPRVTWFKNG-QRLINSNKHEIITTHNHTT----LRVRNTQ 329
             + +G    F  +  GNP+P V W K G Q L+  N+ +   +    +    L + N Q
Sbjct: 323 QIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQ 382

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKA 389
           +SD+G+Y   A      +  +G +  ++  E          +TD     T+    I  + 
Sbjct: 383 RSDAGYYICQA------LTVAGSILAKAQLE----------VTDVL---TDRPPPIILQG 423

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
            A Q + V    D T        C+ TG P P ++W + +       + +  + E G   
Sbjct: 424 PANQTLAV----DGT----ALLKCKATGDPLPVISW-LKEGFTFPGRDPRATIQEQGT-- 472

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
           L I N+ +SD+G  TCVA + SGET++   L+V E    ++  +
Sbjct: 473 LQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNY 516



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 57/193 (29%), Positives = 84/193 (43%), Gaps = 17/193 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
           P F++   ++ V E +   F C+V G P P V W  +D  + R  Y+ K       ++ L
Sbjct: 225 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIK------DDYTL 278

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I     +D G   C+A N+ G+      L V        P+FV R     V +G  V  
Sbjct: 279 RIKKTMSTDEGTYMCIAENRVGKMEASATLTV-----RAPPQFVVRPRDQIVAQGRTVTF 333

Query: 511 NARAVGTPTPRITWQKDGVP--IIPNPELRIHTDGGAS---TLDIPRAKASDAAWYQCTA 565
                G P P + WQK+G    + PN   + ++    S    L I   + SDA +Y C A
Sbjct: 334 PCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQA 393

Query: 566 QNVAGSTATRARL 578
             VAGS   +A+L
Sbjct: 394 LTVAGSILAKAQL 406



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 55/195 (28%), Positives = 82/195 (42%), Gaps = 13/195 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ------IRDDYNHKILVNES 445
           PQFV   +D+ V +G+   F C   G P P V W     Q           N +  V+ +
Sbjct: 314 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 373

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVRE 504
           G+  L ITN+  SD+G   C A   +G    + +L V +       P  ++  +   +  
Sbjct: 374 GD--LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAV 431

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
               +L  +A G P P I+W K+G      +P   I   G   TL I   + SD   Y C
Sbjct: 432 DGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG---TLQIKNLRISDTGTYTC 488

Query: 564 TAQNVAGSTATRARL 578
            A + +G T+  A L
Sbjct: 489 VATSSSGETSWSAVL 503



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 70/293 (23%), Positives = 118/293 (40%), Gaps = 24/293 (8%)

Query: 90  KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149
           +F  +++G+P P V W +  A L    +Y ++      D +L IK+    DEG Y C A 
Sbjct: 243 EFRCQVQGDPQPTVRWKKDDADLPR-GRYDIK-----DDYTLRIKKTMSTDEGTYMCIAE 296

Query: 150 NQYG--EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKV 207
           N+ G  EA  ++ ++                 R V+   E K    Q     Q   +Q +
Sbjct: 297 NRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKG-NPQPAVFWQKEGSQNL 355

Query: 208 AYTNGTDH-------SSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSL 260
            + N           S T D  +   + R        +++T    G    +   E+   L
Sbjct: 356 LFPNQPQQPNSRCSVSPTGDLTITNIQ-RSDAGYYICQALT--VAGSILAKAQLEVTDVL 412

Query: 261 GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
               PP I Q P N  L     A  + + +G+P P ++W K G       +    T    
Sbjct: 413 TDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEG--FTFPGRDPRATIQEQ 470

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            TL+++N + SD+G YT +A + +G    + + AV   TES     ++  ++D
Sbjct: 471 GTLQIKNLRISDTGTYTCVATSSSG---ETSWSAVLDVTESGATISKNYDLSD 520



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 7/98 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-----IPNPELRI 539
           +++   P+ VE  S + V +GEP  LN +A G PTP I W KDG  +      P     +
Sbjct: 25  RQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRML 84

Query: 540 HTDGGASTLDIPRAKAS--DAAWYQCTAQNVAGSTATR 575
              G    L I   + S  D   Y C A+N  G   +R
Sbjct: 85  LPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR 122



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 7/104 (6%)

Query: 635 PPPQFIV-PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
           PPP  +  P     A++G  +    + +  GDP   I WLK G +        +I   G 
Sbjct: 416 PPPIILQGPANQTLAVDGTAL---LKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG- 471

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR-ATIER 736
            +L + +L I D+G YTC A S++G     AVL VT   ATI +
Sbjct: 472 -TLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISK 514



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
            D+   E  V   P F+ +  +  V E E V F C+V+   DP+  + W ++   LP G R
Sbjct: 213  DSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQ--GDPQPTVRWKKDDADLPRG-R 269

Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
            Y    D    +L I    + D G Y+C A N  G+    AT++ +  P  +++
Sbjct: 270  YDIKDD---YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVR 319



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 18/168 (10%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            +RP FL    +   L+E +   F C+V+   DP  T+ W  +   +  G RY    D+  
Sbjct: 223  ERPTFLRRPINQVVLEE-EAVEFRCQVQ--GDPQPTVRWKKDDADLPRG-RYDIKDDY-- 276

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226
              L I  T + D GTYMC A N++G+   + TL V      ++  +         Q+ AQ
Sbjct: 277  -TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRD--------QIVAQ 327

Query: 2227 GHSTRIEVEEPKISPPRFVTELRGTTHVF---EGKTAHFECQVEPVHD 2271
            G +     E      P    +  G+ ++    + +  +  C V P  D
Sbjct: 328  GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD 375



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 56/237 (23%), Positives = 81/237 (34%), Gaps = 14/237 (5%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN-----FPIKNSPDFQIHTFST 4464
            PP F  + +   V +     F  E  G P P + W +E      FP +        + S 
Sbjct: 313  PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 372

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
               L I  +   D+  +   A    G+    A L V +          PP       N  
Sbjct: 373  TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDR----PPPIILQGPANQT 428

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            +       L  K TG     + WLK G           ++E G  TL I      D+G Y
Sbjct: 429  LAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTY 486

Query: 4585 ECVAINSAGEARCDAEC-VVSLPATKDKPKPQTKAANAP--PEIIEPLKDKIVAEGQ 4638
             CVA +S+GE    A   V    AT  K    +     P  P++ +  K+ +    Q
Sbjct: 487  TCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQ 543



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 7/113 (6%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
            + +D  + +V  +P F+ RP + + V+E + V F C+++   D    V W K+   +  G
Sbjct: 212  RDSDPAELTVFERPTFLRRPIN-QVVLEEEAVEFRCQVQG--DPQPTVRWKKDDADLPRG 268

Query: 1491 HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
             R+    D+    L I   ++ D G Y C A N VG  E S  LT R+    V
Sbjct: 269  -RYDIKDDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFV 317



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 7/84 (8%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            +N +V +E + + F C V+    PT  + W  ++  LP G RY    D+   +L I  T 
Sbjct: 232  INQVVLEE-EAVEFRCQVQGDPQPT--VRWKKDDADLPRG-RYDIKDDY---TLRIKKTM 284

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
              D G Y C A N  G    S +L
Sbjct: 285  STDEGTYMCIAENRVGKMEASATL 308



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 19/140 (13%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I  T +TD GTY C A N+ G+ E S  L     +    P+F    ++ + +  G++ 
Sbjct: 278  LRIKKTMSTDEGTYMCIAENRVGKMEASATL-----TVRAPPQFVVRPRD-QIVAQGRTV 331

Query: 3168 HFECTVVPVDDPDMKIEWYHNG--------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
             F C      +P   + W   G        QP + ++R  +VS  G   L I   Q  D+
Sbjct: 332  TFPCET--KGNPQPAVFWQKEGSQNLLFPNQPQQPNSRC-SVSPTG--DLTITNIQRSDA 386

Query: 3220 GEYVCRAYNKYGEDFTRATI 3239
            G Y+C+A    G    +A +
Sbjct: 387  GYYICQALTVAGSILAKAQL 406



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PPI  Q   N   A  G A  + K  G+P PV+SW ++       +  +    + T    
Sbjct: 417 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT---- 472

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L IK +   D G YTC A +  GE   S  +
Sbjct: 473 LQIKNLRISDTGTYTCVATSSSGETSWSAVL 503



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 11/132 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I  T+ +D+G Y+C  TN  G+ +     +  + +  ++P F     N   L++ ++ 
Sbjct: 188  LMISNTRKSDAGMYTCVGTNMVGERD----SDPAELTVFERPTFLRRPINQVVLEE-EAV 242

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             F C V    DP   + W  +   +    R     D+    L I  T + D G Y+C A 
Sbjct: 243  EFRCQV--QGDPQPTVRWKKDDADLPRG-RYDIKDDY---TLRIKKTMSTDEGTYMCIAE 296

Query: 3228 NKYGEDFTRATI 3239
            N+ G+    AT+
Sbjct: 297  NRVGKMEASATL 308



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   + WL+ G      +   T+ + G   L +K +   D+GTYTC A +  GE   S
Sbjct: 443  GDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSWS 500

Query: 1798 STLFV 1802
            + L V
Sbjct: 501  AVLDV 505



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)

Query: 1834 EDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
            +  E+ V + P F+ +      L E ++  + C+++  P P +R  W  +   L  G RY
Sbjct: 215  DPAELTVFERPTFLRRPINQVVLEE-EAVEFRCQVQGDPQPTVR--WKKDDADLPRG-RY 270

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
               +D+    L I      D G Y C A N +G+  +S  L V++    +
Sbjct: 271  DIKDDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFV 317



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 7/95 (7%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT- 126
           E  PP   +   +   ++G       K  G PTP + W  K    VE +K   R +    
Sbjct: 27  EDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWY-KDGERVETDKDDPRSHRMLL 85

Query: 127 GDVSLLIKQIGPG-----DEGEYTCTARNQYGEAI 156
              SL   +I  G     DEG Y C ARN  GEA+
Sbjct: 86  PSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV 120



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 6/107 (5%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++TV + P F R   N   +E   V   C++Q  GD    V W  +   +  G   R   
Sbjct: 218  ELTVFERPTFLRRPINQVVLEEEAVEFRCQVQ--GDPQPTVRWKKDDADLPRG---RYDI 272

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
            + DY  L +      D G Y C A N++G+   S  L V A    ++
Sbjct: 273  KDDYT-LRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVV 318



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TGD   VI W   G T        T+   G   L+I   + +D+GTY+C AT+  G+   
Sbjct: 442  TGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSW 499

Query: 3135 SVKLECVD 3142
            S  L+  +
Sbjct: 500  SAVLDVTE 507



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 8/99 (8%)

Query: 1707 ITQAPVFTM-PMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + P F   P+  + V E +A  F  ++   GDP+  V W ++   +    R     D+
Sbjct: 221  VFERPTFLRRPINQV-VLEEEAVEFRCQV--QGDPQPTVRWKKDDADLPRG-RYDIKDDY 276

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
                L +K     D GTY C A N +G+   S+TL V++
Sbjct: 277  ---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA 312



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DP   I W K G T   G   ++T      TL I +LR  D+G YTC AT+  GE   +A
Sbjct: 444  DPLPVISWLKEGFTFP-GRDPRATIQ-EQGTLQIKNLRISDTGTYTCVATSSSGETSWSA 501

Query: 2731 SIKIED 2736
             + + +
Sbjct: 502  VLDVTE 507



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/72 (38%), Positives = 35/72 (48%), Gaps = 8/72 (11%)

Query: 800 PTMRVEWYKDGRPITAS-----SRITSIFNFGYVSLNIMHLRAE--DAGSYTVRAVNKLG 852
           PT  +EWYKDG  +        S    + +     L I+H R    D GSY   A N LG
Sbjct: 58  PTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLG 117

Query: 853 EAIS-TASIRVA 863
           EA+S  AS+ VA
Sbjct: 118 EAVSRNASLEVA 129



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 16/117 (13%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK---LLPSGHRYR--- 3879
            V  PP+F+ + +   V +   V F C  E K +P+  + W + G    L P+  +     
Sbjct: 310  VRAPPQFVVRPRDQIVAQGRTVTFPC--ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSR 367

Query: 3880 -TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL-----PDIILQ 3930
             +V   G   L I  +   D+G YIC+A+   G    KA +    +     P IILQ
Sbjct: 368  CSVSPTG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQ 422



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 5/124 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD    + WLK+G          T    G   L IK++ + D G YTC A ++ G+ + S
Sbjct: 443  GDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSWS 500

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIV 1056
            A L +      I+++     L  +       + +  T+  V ++ +P   G L  +  I+
Sbjct: 501  AVLDVTESGATISKNY---DLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYII 557

Query: 1057 EGQS 1060
            E  S
Sbjct: 558  EAFS 561



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 7/100 (7%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ + ++P FL   +  N++V  + A  E R + Q D   TV W  +   +    R    
Sbjct: 218  ELTVFERPTFLR--RPINQVVLEEEA-VEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIK 273

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             D+    L I    + D G Y  +A N  G+ + SA++TV
Sbjct: 274  DDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 310



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/77 (28%), Positives = 31/77 (40%)

Query: 4073 YDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCC 4132
            Y  ++ K M + E      A  +V   +       R PP FV  P    V +G    F C
Sbjct: 276  YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPC 335

Query: 4133 RVTGHPKPRVMWLLNGN 4149
               G+P+P V W   G+
Sbjct: 336  ETKGNPQPAVFWQKEGS 352



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 11/107 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTL--- 3747
            PPR  VE   ++ V +G P   +C+ E  G PT  I+W+ +G    T     R H +   
Sbjct: 30   PPRI-VEHPSDVIVSKGEPTTLNCKAE--GRPTPTIEWYKDGERVETDKDDPRSHRMLLP 86

Query: 3748 -NDFGFIALDIDYIYARDAGEYTCRATNKWGSATT-TAKITCSAKRD 3792
                 F+ +        D G Y C A N  G A +  A +  +  RD
Sbjct: 87   SGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD 133



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 4/69 (5%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   LE Q  PR  P   I W K+ V +      + +   G   L I++ R  D+G+YT
Sbjct: 147  GEPAILECQ-PPRGHPEPTIYWKKDKVRIDDKEE-RISIRGG--KLMISNTRKSDAGMYT 202

Query: 2717 CKATNLLGE 2725
            C  TN++GE
Sbjct: 203  CVGTNMVGE 211



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 6/103 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   P + ++ E  +  F C++    D    V W  +   L  G R    +D+    L
Sbjct: 225  PTFLRRPINQVVLEEEAVEFRCQV--QGDPQPTVRWKKDDADLPRG-RYDIKDDY---TL 278

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             I      D G Y C A NR G+   S  L V+     ++ P+
Sbjct: 279  RIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPR 321



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 3/68 (4%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIP 4170
            P F+  P    V E E   F C+V G P+P V W  +   +  G RY +  D  Y   I 
Sbjct: 225  PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDD--YTLRIK 281

Query: 4171 KTRQYDTG 4178
            KT   D G
Sbjct: 282  KTMSTDEG 289



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 13/105 (12%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASSR 684
           V  PPQF+V  +     +G  + F    E  G+P   + W K G        Q  + +SR
Sbjct: 310 VRAPPQFVVRPRDQIVAQGRTVTFPC--ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSR 367

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             S+   G   L + ++   D+G Y C+A++  G    KA L VT
Sbjct: 368 -CSVSPTG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVT 409



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 12/133 (9%)

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Y R +   +     P  I +      +S+G+     C+ E  P P   +EWY +G+ +++
Sbjct: 16   YVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPT--IEWYKDGERVET 73

Query: 1890 GHRYRTSNDFGFAALDIL---TVYGE----DSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
                  S+     +  +     V+G     D G Y C A N LG+AVS    N   + ++
Sbjct: 74   DKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR---NASLEVAL 130

Query: 1943 IRDSQHESALEKI 1955
            +RD   ++  + +
Sbjct: 131  LRDDFRQNPTDVV 143



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E+P F +   N  V E   V     +    DP   V W  +   + +G R+    D+ 
Sbjct: 221  VFERPTFLRRPINQVVLEEEAVEFRCQVQ--GDPQPTVRWKKDDADLPRG-RYDIKDDY- 276

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
               L I    + D GTYMC A N VG+   ++++ V A
Sbjct: 277  --TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA 312



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 2505 FEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG 2564
            FE+P F   L  P      +    E R    GDP     W  +  +L  G R+    D+ 
Sbjct: 222  FERPTF---LRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDDY- 276

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAG 2590
              TL I   ++ D G YMC A NR G
Sbjct: 277  --TLRIKKTMSTDEGTYMCIAENRVG 300



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 12/112 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL------PSGHRYRTVY 3882
            PP+ +       V + E     C+ E +  P   IEWY++G+ +      P  HR     
Sbjct: 30   PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPT--IEWYKDGERVETDKDDPRSHRMLLPS 87

Query: 3883 DMGFVSLDILYVYAE--DSGEYICRAVNDFGEDFTK-ATISCKKLPDIILQN 3931
               F  L I++      D G Y+C A N  GE  ++ A++    L D   QN
Sbjct: 88   GSLFF-LRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQN 138



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLR------- 2708
            +G+   L  + E R  P   IEW+K+G  + T      +    L + S+  LR       
Sbjct: 44   KGEPTTLNCKAEGRPTPT--IEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 101

Query: 2709 NDDSGIYTCKATNLLGEAVS-TASIKI 2734
              D G Y C A N LGEAVS  AS+++
Sbjct: 102  KPDEGSYVCVARNYLGEAVSRNASLEV 128



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-----MTISHVR 2442
            + +G+    +C+    G PT  +EW+++ + +E      ++H     S     + I H R
Sbjct: 42   VSKGEPTTLNCKA--EGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 99

Query: 2443 DE--DEGVYMCRASNLLGE 2459
                DEG Y+C A N LGE
Sbjct: 100  RSKPDEGSYVCVARNYLGE 118



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P++  L+ + +A  +C+     D    + W   G          TI + G   
Sbjct: 417  PPIILQGPANQTLAVDGTALLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG--T 472

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L+I  +   D G YTC AT+  GE + S  L V
Sbjct: 473  LQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 505



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 39/180 (21%), Positives = 61/180 (33%), Gaps = 10/180 (5%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   + +D+G Y C+A    G      +LE  D    + P         + L    +A
Sbjct: 376  LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTA 435

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
              +C      DP   I W   G          T+ + G   L I   +  D+G Y C A 
Sbjct: 436  LLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVAT 491

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQ------PDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            +  GE    A ++    G    ++        P S  ++ ++          P TP   P
Sbjct: 492  SSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLP 551



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 4/90 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP   ++   N  +   G     C+    GDP   I W   G  F       T+ + G  
Sbjct: 416  PPPIILQGPANQTLAVDGTALLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG-- 471

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
             L I  +   D G YTC AT+  G  + +A
Sbjct: 472  TLQIKNLRISDTGTYTCVATSSSGETSWSA 501


>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
          Length = 1394

 Score =  121 bits (292), Expect = 6e-26
 Identities = 110/414 (26%), Positives = 171/414 (41%), Gaps = 48/414 (11%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI---KNSPDFQIHTFSTKS 4466
            PP   +      V + E      + +G P P I+WY++   +   K+ P        + S
Sbjct: 46   PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 105

Query: 4467 ILIIRQVFVE----DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            +  +R V       D   +  VA N  G A  S N  +E         ++   F     +
Sbjct: 106  LFFLRIVHGRRSKPDEGSYVCVARNYLGEA-VSRNASLEV-------ALLRDDFRQNPTD 157

Query: 4523 VNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            V V +G+   L+ +     P   +YW K+  KV+ D + + +   G   L+I      D+
Sbjct: 158  VVVAAGEPAILECQPPRGHPEPTIYWKKD--KVRIDDKEERISIRGG-KLMISNTRKSDA 214

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G Y CV  N  GE              +D    +      P  +  P+ +++V E +A+E
Sbjct: 215  GMYTCVGTNMVGE--------------RDSDPAELTVFERPTFLRRPI-NQVVLEEEAVE 259

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            F C++ G P PTV+W K D  +   +Y       D+YTLRI +    DEG Y C+A N  
Sbjct: 260  FRCQVQGDPQPTVRWKKDDADLPRGRY----DIKDDYTLRIKKTMSTDEGTYMCIAENRV 315

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-- 4759
            G++  +A L V  P Q    P     RD +V +G+   F  +     +P + W +EG+  
Sbjct: 316  GKMEASATLTVRAPPQFVVRP-----RDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQN 370

Query: 4760 -LIPETPD--FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L P  P              L I N    D G + C+A T AG +   A+L V
Sbjct: 371  LLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 424



 Score =  105 bits (252), Expect = 4e-21
 Identities = 110/383 (28%), Positives = 157/383 (40%), Gaps = 44/383 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I +  + +I     K  L+I      D+ ++  V  N  G     
Sbjct: 175  GHPEPTIYWKKDKVRIDDKEE-RISIRGGK--LMISNTRKSDAGMYTCVGTNMVGERDSD 231

Query: 4496 -ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
             A L V E+          P+F     N  V   + V    +V G     V W K+   +
Sbjct: 232  PAELTVFER----------PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL 281

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R  I ++   YTL I +    D G Y C+A N  G+    A               
Sbjct: 282  -PRGRYDIKDD---YTLRIKKTMSTDEGTYMCIAENRVGKMEASA--------------- 322

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYFQM- 4671
             T    APP+ +   +D+IVA+G+ + F C+  G P P V W K     L+ P++  Q  
Sbjct: 323  -TLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPN 381

Query: 4672 SRTADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ--PDQADNLPALTPL 4727
            SR +   T  L I+     D G Y C A   AG +   A+L+VT    D+   +    P 
Sbjct: 382  SRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPA 441

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
               +  +G  A  K + T    P I WL+EG   P       I E     L I N    D
Sbjct: 442  NQTLAVDGT-ALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE--QGTLQIKNLRISD 498

Query: 4788 TGTFTCRATTAAGQVETSAKLVV 4810
            TGT+TC AT+++G+   SA L V
Sbjct: 499  TGTYTCVATSSSGETSWSAVLDV 521



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 87/350 (24%), Positives = 140/350 (40%), Gaps = 38/350 (10%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F ++     V E E   F  +  G+P P ++W +++  +        +       L I
Sbjct: 241  PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGR----YDIKDDYTLRI 296

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            ++    D   +  +AENR G  + SA L V            PP F +  ++  V  G+ 
Sbjct: 297  KKTMSTDEGTYMCIAENRVGKMEASATLTVR----------APPQFVVRPRDQIVAQGRT 346

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKV-----QPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            V    +  G     V+W K G +      QP   N       T  L I      D+G Y 
Sbjct: 347  VTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI 406

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLKDKIVAEGQAIEFSC 4644
            C A+  AG     A+  V+   T D+P         PP I++ P    +  +G A+   C
Sbjct: 407  CQALTVAGSILAKAQLEVTDVLT-DRP---------PPIILQGPANQTLAVDGTAL-LKC 455

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            K  G PLP + W K +    P +    +   ++ TL+I      D G Y CVA +S+G  
Sbjct: 456  KATGDPLPVISWLK-EGFTFPGRD-PRATIQEQGTLQIKNLRISDTGTYTCVATSSSGET 513

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
            + +A L VT+         ++   D+    G P++ +    +K   T+ W
Sbjct: 514  SWSAVLDVTESG-----ATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW 558



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 83/309 (26%), Positives = 129/309 (41%), Gaps = 35/309 (11%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-----PDIRNKILEEDG 4567
            PP       +V V+ G+   L+ K  G     + W K+G++V+     P     +L    
Sbjct: 46   PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 105

Query: 4568 TYTLLILEA--YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             + L I+       D G Y CVA N  GEA       VS  A+ +    +      P ++
Sbjct: 106  LFFLRIVHGRRSKPDEGSYVCVARNYLGEA-------VSRNASLEVALLRDDFRQNPTDV 158

Query: 4626 IEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
                   +VA G+     C+   G P PT+ W K DK+    K  ++S    +  L IS 
Sbjct: 159  -------VVAAGEPAILECQPPRGHPEPTIYW-KKDKVRIDDKEERISIRGGK--LMISN 208

Query: 4685 AFPEDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                D G Y CV  N  G R +  A+L V +       P      + VV E +  +F+ Q
Sbjct: 209  TRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPI-----NQVVLEEEAVEFRCQ 263

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            +    +PT++W ++ A +P           ++  L I  T   D GT+ C A    G++E
Sbjct: 264  VQGDPQPTVRWKKDDADLPR----GRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKME 319

Query: 4804 TSAKLVVKS 4812
             SA L V++
Sbjct: 320  ASATLTVRA 328



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 81/317 (25%), Positives = 125/317 (39%), Gaps = 41/317 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+I + P +  + +G       +  G P P + W+K+G+R+                  
Sbjct: 46  PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERV------------------ 87

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-SYVQDQRSQYITDTQQRETEERI 383
              T K D   + +L  + +   +   +     P E SYV   R+ Y+ +   R     +
Sbjct: 88  --ETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARN-YLGEAVSRNASLEV 144

Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILV 442
            +    L   F +   D  V  G+    +C+   G P P + W   D+   DD   +I +
Sbjct: 145 AL----LRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWK-KDKVRIDDKEERISI 199

Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGE-TAFQCRLNVIEKEQVVAPKFVERFSTLN 501
                  LMI+N   SD+G+ TCV  N  GE  +    L V E+     P F+ R     
Sbjct: 200 RGG---KLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFER-----PTFLRRPINQV 251

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V E E V    +  G P P + W+KD    +P     I  D    TL I +  ++D   Y
Sbjct: 252 VLEEEAVEFRCQVQGDPQPTVRWKKDDAD-LPRGRYDIKDD---YTLRIKKTMSTDEGTY 307

Query: 562 QCTAQNVAGSTATRARL 578
            C A+N  G     A L
Sbjct: 308 MCIAENRVGKMEASATL 324



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 13/193 (6%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR----DDYNHKI 440
           + ++   P+ V+   D  V++G+ T  +C+  GRP P + W+ +  ++     D  +H++
Sbjct: 40  LRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRM 99

Query: 441 LVNESGNHALMITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498
           L+       L I +   S  D G   CVARN  GE   +   N   +  ++   F +  +
Sbjct: 100 LLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR---NASLEVALLRDDFRQNPT 156

Query: 499 TLNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            + V  GEP +L  +   G P P I W+KD V  I + E RI   GG   L I   + SD
Sbjct: 157 DVVVAAGEPAILECQPPRGHPEPTIYWKKDKVR-IDDKEERISIRGG--KLMISNTRKSD 213

Query: 558 AAWYQCTAQNVAG 570
           A  Y C   N+ G
Sbjct: 214 AGMYTCVGTNMVG 226



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 96/404 (23%), Positives = 163/404 (40%), Gaps = 51/404 (12%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P + W + K   V  +    R + + G   L+I      D G YTC   N  GE 
Sbjct: 174 RGHPEPTIYWKKDK---VRIDDKEERISIRGG--KLMISNTRKSDAGMYTCVGTNMVGE- 227

Query: 156 ICSVYIQPEGXXXXXXXXXXXXXYRHVSETV-EHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                 +                 R +++ V E +A   +       + T +    +   
Sbjct: 228 ------RDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL 281

Query: 215 HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
                D K D +  R+ + +S  E  T   + E+ V    E   +L   +PP+   +PR+
Sbjct: 282 PRGRYDIK-DDYTLRIKKTMSTDEG-TYMCIAENRVG-KMEASATLTVRAPPQFVVRPRD 338

Query: 275 SKLQEGADAQFQVQLSGNPRPRVTWFKNG-QRLINSNKHEIITTHNHTT----LRVRNTQ 329
             + +G    F  +  GNP+P V W K G Q L+  N+ +   +    +    L + N Q
Sbjct: 339 QIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQ 398

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKA 389
           +SD+G+Y   A      +  +G +  ++  E          +TD     T+    I  + 
Sbjct: 399 RSDAGYYICQA------LTVAGSILAKAQLE----------VTDVL---TDRPPPIILQG 439

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
            A Q + V    D T        C+ TG P P ++W + +       + +  + E G   
Sbjct: 440 PANQTLAV----DGT----ALLKCKATGDPLPVISW-LKEGFTFPGRDPRATIQEQGT-- 488

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
           L I N+ +SD+G  TCVA + SGET++   L+V E    ++  +
Sbjct: 489 LQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNY 532



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 57/193 (29%), Positives = 84/193 (43%), Gaps = 17/193 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
           P F++   ++ V E +   F C+V G P P V W  +D  + R  Y+ K       ++ L
Sbjct: 241 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIK------DDYTL 294

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I     +D G   C+A N+ G+      L V        P+FV R     V +G  V  
Sbjct: 295 RIKKTMSTDEGTYMCIAENRVGKMEASATLTV-----RAPPQFVVRPRDQIVAQGRTVTF 349

Query: 511 NARAVGTPTPRITWQKDGVP--IIPNPELRIHTDGGAS---TLDIPRAKASDAAWYQCTA 565
                G P P + WQK+G    + PN   + ++    S    L I   + SDA +Y C A
Sbjct: 350 PCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQA 409

Query: 566 QNVAGSTATRARL 578
             VAGS   +A+L
Sbjct: 410 LTVAGSILAKAQL 422



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 55/195 (28%), Positives = 82/195 (42%), Gaps = 13/195 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ------IRDDYNHKILVNES 445
           PQFV   +D+ V +G+   F C   G P P V W     Q           N +  V+ +
Sbjct: 330 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 389

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVRE 504
           G+  L ITN+  SD+G   C A   +G    + +L V +       P  ++  +   +  
Sbjct: 390 GD--LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAV 447

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
               +L  +A G P P I+W K+G      +P   I   G   TL I   + SD   Y C
Sbjct: 448 DGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG---TLQIKNLRISDTGTYTC 504

Query: 564 TAQNVAGSTATRARL 578
            A + +G T+  A L
Sbjct: 505 VATSSSGETSWSAVL 519



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 70/293 (23%), Positives = 118/293 (40%), Gaps = 24/293 (8%)

Query: 90  KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149
           +F  +++G+P P V W +  A L    +Y ++      D +L IK+    DEG Y C A 
Sbjct: 259 EFRCQVQGDPQPTVRWKKDDADLPR-GRYDIK-----DDYTLRIKKTMSTDEGTYMCIAE 312

Query: 150 NQYG--EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKV 207
           N+ G  EA  ++ ++                 R V+   E K    Q     Q   +Q +
Sbjct: 313 NRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKG-NPQPAVFWQKEGSQNL 371

Query: 208 AYTNGTDH-------SSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSL 260
            + N           S T D  +   + R        +++T    G    +   E+   L
Sbjct: 372 LFPNQPQQPNSRCSVSPTGDLTITNIQ-RSDAGYYICQALT--VAGSILAKAQLEVTDVL 428

Query: 261 GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
               PP I Q P N  L     A  + + +G+P P ++W K G       +    T    
Sbjct: 429 TDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEG--FTFPGRDPRATIQEQ 486

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            TL+++N + SD+G YT +A + +G    + + AV   TES     ++  ++D
Sbjct: 487 GTLQIKNLRISDTGTYTCVATSSSG---ETSWSAVLDVTESGATISKNYDLSD 536



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 7/98 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-----IPNPELRI 539
           +++   P+ VE  S + V +GEP  LN +A G PTP I W KDG  +      P     +
Sbjct: 41  RQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRML 100

Query: 540 HTDGGASTLDIPRAKAS--DAAWYQCTAQNVAGSTATR 575
              G    L I   + S  D   Y C A+N  G   +R
Sbjct: 101 LPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR 138



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 7/104 (6%)

Query: 635 PPPQFIV-PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
           PPP  +  P     A++G  +    + +  GDP   I WLK G +        +I   G 
Sbjct: 432 PPPIILQGPANQTLAVDGTAL---LKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG- 487

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR-ATIER 736
            +L + +L I D+G YTC A S++G     AVL VT   ATI +
Sbjct: 488 -TLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISK 530



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
            D+   E  V   P F+ +  +  V E E V F C+V+   DP+  + W ++   LP G R
Sbjct: 229  DSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQ--GDPQPTVRWKKDDADLPRG-R 285

Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
            Y    D    +L I    + D G Y+C A N  G+    AT++ +  P  +++
Sbjct: 286  YDIKDD---YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVR 335



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 18/168 (10%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            +RP FL    +   L+E +   F C+V+   DP  T+ W  +   +  G RY    D+  
Sbjct: 239  ERPTFLRRPINQVVLEE-EAVEFRCQVQ--GDPQPTVRWKKDDADLPRG-RYDIKDDY-- 292

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226
              L I  T + D GTYMC A N++G+   + TL V      ++  +         Q+ AQ
Sbjct: 293  -TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRD--------QIVAQ 343

Query: 2227 GHSTRIEVEEPKISPPRFVTELRGTTHVF---EGKTAHFECQVEPVHD 2271
            G +     E      P    +  G+ ++    + +  +  C V P  D
Sbjct: 344  GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD 391



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 56/237 (23%), Positives = 81/237 (34%), Gaps = 14/237 (5%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN-----FPIKNSPDFQIHTFST 4464
            PP F  + +   V +     F  E  G P P + W +E      FP +        + S 
Sbjct: 329  PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 388

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
               L I  +   D+  +   A    G+    A L V +          PP       N  
Sbjct: 389  TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDR----PPPIILQGPANQT 444

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            +       L  K TG     + WLK G           ++E G  TL I      D+G Y
Sbjct: 445  LAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTY 502

Query: 4585 ECVAINSAGEARCDAEC-VVSLPATKDKPKPQTKAANAP--PEIIEPLKDKIVAEGQ 4638
             CVA +S+GE    A   V    AT  K    +     P  P++ +  K+ +    Q
Sbjct: 503  TCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQ 559



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 7/113 (6%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
            + +D  + +V  +P F+ RP + + V+E + V F C+++   D    V W K+   +  G
Sbjct: 228  RDSDPAELTVFERPTFLRRPIN-QVVLEEEAVEFRCQVQG--DPQPTVRWKKDDADLPRG 284

Query: 1491 HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
             R+    D+    L I   ++ D G Y C A N VG  E S  LT R+    V
Sbjct: 285  -RYDIKDDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFV 333



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 7/84 (8%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            +N +V +E + + F C V+    PT  + W  ++  LP G RY    D+   +L I  T 
Sbjct: 248  INQVVLEE-EAVEFRCQVQGDPQPT--VRWKKDDADLPRG-RYDIKDDY---TLRIKKTM 300

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
              D G Y C A N  G    S +L
Sbjct: 301  STDEGTYMCIAENRVGKMEASATL 324



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 19/140 (13%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I  T +TD GTY C A N+ G+ E S  L     +    P+F    ++ + +  G++ 
Sbjct: 294  LRIKKTMSTDEGTYMCIAENRVGKMEASATL-----TVRAPPQFVVRPRD-QIVAQGRTV 347

Query: 3168 HFECTVVPVDDPDMKIEWYHNG--------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
             F C      +P   + W   G        QP + ++R  +VS  G   L I   Q  D+
Sbjct: 348  TFPCET--KGNPQPAVFWQKEGSQNLLFPNQPQQPNSRC-SVSPTG--DLTITNIQRSDA 402

Query: 3220 GEYVCRAYNKYGEDFTRATI 3239
            G Y+C+A    G    +A +
Sbjct: 403  GYYICQALTVAGSILAKAQL 422



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PPI  Q   N   A  G A  + K  G+P PV+SW ++       +  +    + T    
Sbjct: 433 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT---- 488

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L IK +   D G YTC A +  GE   S  +
Sbjct: 489 LQIKNLRISDTGTYTCVATSSSGETSWSAVL 519



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 11/132 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I  T+ +D+G Y+C  TN  G+ +     +  + +  ++P F     N   L++ ++ 
Sbjct: 204  LMISNTRKSDAGMYTCVGTNMVGERD----SDPAELTVFERPTFLRRPINQVVLEE-EAV 258

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             F C V    DP   + W  +   +    R     D+    L I  T + D G Y+C A 
Sbjct: 259  EFRCQV--QGDPQPTVRWKKDDADLPRG-RYDIKDDY---TLRIKKTMSTDEGTYMCIAE 312

Query: 3228 NKYGEDFTRATI 3239
            N+ G+    AT+
Sbjct: 313  NRVGKMEASATL 324



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   + WL+ G      +   T+ + G   L +K +   D+GTYTC A +  GE   S
Sbjct: 459  GDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSWS 516

Query: 1798 STLFV 1802
            + L V
Sbjct: 517  AVLDV 521



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)

Query: 1834 EDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
            +  E+ V + P F+ +      L E ++  + C+++  P P +R  W  +   L  G RY
Sbjct: 231  DPAELTVFERPTFLRRPINQVVLEE-EAVEFRCQVQGDPQPTVR--WKKDDADLPRG-RY 286

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
               +D+    L I      D G Y C A N +G+  +S  L V++    +
Sbjct: 287  DIKDDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFV 333



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 7/95 (7%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT- 126
           E  PP   +   +   ++G       K  G PTP + W  K    VE +K   R +    
Sbjct: 43  EDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWY-KDGERVETDKDDPRSHRMLL 101

Query: 127 GDVSLLIKQIGPG-----DEGEYTCTARNQYGEAI 156
              SL   +I  G     DEG Y C ARN  GEA+
Sbjct: 102 PSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV 136



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 6/107 (5%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++TV + P F R   N   +E   V   C++Q  GD    V W  +   +  G   R   
Sbjct: 234  ELTVFERPTFLRRPINQVVLEEEAVEFRCQVQ--GDPQPTVRWKKDDADLPRG---RYDI 288

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
            + DY  L +      D G Y C A N++G+   S  L V A    ++
Sbjct: 289  KDDYT-LRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVV 334



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TGD   VI W   G T        T+   G   L+I   + +D+GTY+C AT+  G+   
Sbjct: 458  TGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSW 515

Query: 3135 SVKLECVD 3142
            S  L+  +
Sbjct: 516  SAVLDVTE 523



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 8/99 (8%)

Query: 1707 ITQAPVFTM-PMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + P F   P+  + V E +A  F  ++   GDP+  V W ++   +    R     D+
Sbjct: 237  VFERPTFLRRPINQV-VLEEEAVEFRCQV--QGDPQPTVRWKKDDADLPRG-RYDIKDDY 292

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
                L +K     D GTY C A N +G+   S+TL V++
Sbjct: 293  ---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA 328



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DP   I W K G T   G   ++T      TL I +LR  D+G YTC AT+  GE   +A
Sbjct: 460  DPLPVISWLKEGFTFP-GRDPRATIQ-EQGTLQIKNLRISDTGTYTCVATSSSGETSWSA 517

Query: 2731 SIKIED 2736
             + + +
Sbjct: 518  VLDVTE 523



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/72 (38%), Positives = 35/72 (48%), Gaps = 8/72 (11%)

Query: 800 PTMRVEWYKDGRPITAS-----SRITSIFNFGYVSLNIMHLRAE--DAGSYTVRAVNKLG 852
           PT  +EWYKDG  +        S    + +     L I+H R    D GSY   A N LG
Sbjct: 74  PTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLG 133

Query: 853 EAIS-TASIRVA 863
           EA+S  AS+ VA
Sbjct: 134 EAVSRNASLEVA 145



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 16/117 (13%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK---LLPSGHRYR--- 3879
            V  PP+F+ + +   V +   V F C  E K +P+  + W + G    L P+  +     
Sbjct: 326  VRAPPQFVVRPRDQIVAQGRTVTFPC--ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSR 383

Query: 3880 -TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL-----PDIILQ 3930
             +V   G   L I  +   D+G YIC+A+   G    KA +    +     P IILQ
Sbjct: 384  CSVSPTG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQ 438



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 5/124 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD    + WLK+G          T    G   L IK++ + D G YTC A ++ G+ + S
Sbjct: 459  GDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSWS 516

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIV 1056
            A L +      I+++     L  +       + +  T+  V ++ +P   G L  +  I+
Sbjct: 517  AVLDVTESGATISKNY---DLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYII 573

Query: 1057 EGQS 1060
            E  S
Sbjct: 574  EAFS 577



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 7/100 (7%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ + ++P FL   +  N++V  + A  E R + Q D   TV W  +   +    R    
Sbjct: 234  ELTVFERPTFLR--RPINQVVLEEEA-VEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIK 289

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             D+    L I    + D G Y  +A N  G+ + SA++TV
Sbjct: 290  DDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 326



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/77 (28%), Positives = 31/77 (40%)

Query: 4073 YDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCC 4132
            Y  ++ K M + E      A  +V   +       R PP FV  P    V +G    F C
Sbjct: 292  YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPC 351

Query: 4133 RVTGHPKPRVMWLLNGN 4149
               G+P+P V W   G+
Sbjct: 352  ETKGNPQPAVFWQKEGS 368



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 11/107 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTL--- 3747
            PPR  VE   ++ V +G P   +C+ E  G PT  I+W+ +G    T     R H +   
Sbjct: 46   PPRI-VEHPSDVIVSKGEPTTLNCKAE--GRPTPTIEWYKDGERVETDKDDPRSHRMLLP 102

Query: 3748 -NDFGFIALDIDYIYARDAGEYTCRATNKWGSATT-TAKITCSAKRD 3792
                 F+ +        D G Y C A N  G A +  A +  +  RD
Sbjct: 103  SGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD 149



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 4/69 (5%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   LE Q  PR  P   I W K+ V +      + +   G   L I++ R  D+G+YT
Sbjct: 163  GEPAILECQ-PPRGHPEPTIYWKKDKVRIDDKEE-RISIRGG--KLMISNTRKSDAGMYT 218

Query: 2717 CKATNLLGE 2725
            C  TN++GE
Sbjct: 219  CVGTNMVGE 227



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 6/103 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   P + ++ E  +  F C++    D    V W  +   L  G R    +D+    L
Sbjct: 241  PTFLRRPINQVVLEEEAVEFRCQV--QGDPQPTVRWKKDDADLPRG-RYDIKDDY---TL 294

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             I      D G Y C A NR G+   S  L V+     ++ P+
Sbjct: 295  RIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPR 337



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 3/68 (4%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIP 4170
            P F+  P    V E E   F C+V G P+P V W  +   +  G RY +  D  Y   I 
Sbjct: 241  PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDD--YTLRIK 297

Query: 4171 KTRQYDTG 4178
            KT   D G
Sbjct: 298  KTMSTDEG 305



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 13/105 (12%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASSR 684
           V  PPQF+V  +     +G  + F    E  G+P   + W K G        Q  + +SR
Sbjct: 326 VRAPPQFVVRPRDQIVAQGRTVTFPC--ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSR 383

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             S+   G   L + ++   D+G Y C+A++  G    KA L VT
Sbjct: 384 -CSVSPTG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVT 425



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E+P F +   N  V E   V     +    DP   V W  +   + +G R+    D+ 
Sbjct: 237  VFERPTFLRRPINQVVLEEEAVEFRCQVQ--GDPQPTVRWKKDDADLPRG-RYDIKDDY- 292

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
               L I    + D GTYMC A N VG+   ++++ V A
Sbjct: 293  --TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA 328



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 2505 FEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG 2564
            FE+P F   L  P      +    E R    GDP     W  +  +L  G R+    D+ 
Sbjct: 238  FERPTF---LRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDDY- 292

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAG 2590
              TL I   ++ D G YMC A NR G
Sbjct: 293  --TLRIKKTMSTDEGTYMCIAENRVG 316



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 12/112 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL------PSGHRYRTVY 3882
            PP+ +       V + E     C+ E +  P   IEWY++G+ +      P  HR     
Sbjct: 46   PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPT--IEWYKDGERVETDKDDPRSHRMLLPS 103

Query: 3883 DMGFVSLDILYVYAE--DSGEYICRAVNDFGEDFTK-ATISCKKLPDIILQN 3931
               F  L I++      D G Y+C A N  GE  ++ A++    L D   QN
Sbjct: 104  GSLFF-LRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQN 154



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 12/107 (11%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL---TVYGE 1912
            +S+G+     C+ E  P P   +EWY +G+ +++      S+     +  +     V+G 
Sbjct: 58   VSKGEPTTLNCKAEGRPTPT--IEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 115

Query: 1913 ----DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
                D G Y C A N LG+AVS    N   + +++RD   ++  + +
Sbjct: 116  RSKPDEGSYVCVARNYLGEAVSR---NASLEVALLRDDFRQNPTDVV 159



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLR------- 2708
            +G+   L  + E R  P   IEW+K+G  + T      +    L + S+  LR       
Sbjct: 60   KGEPTTLNCKAEGRPTPT--IEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 117

Query: 2709 NDDSGIYTCKATNLLGEAVS-TASIKI 2734
              D G Y C A N LGEAVS  AS+++
Sbjct: 118  KPDEGSYVCVARNYLGEAVSRNASLEV 144



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-----MTISHVR 2442
            + +G+    +C+    G PT  +EW+++ + +E      ++H     S     + I H R
Sbjct: 58   VSKGEPTTLNCKA--EGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 115

Query: 2443 DE--DEGVYMCRASNLLGE 2459
                DEG Y+C A N LGE
Sbjct: 116  RSKPDEGSYVCVARNYLGE 134



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P++  L+ + +A  +C+     D    + W   G          TI + G   
Sbjct: 433  PPIILQGPANQTLAVDGTALLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG--T 488

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L+I  +   D G YTC AT+  GE + S  L V
Sbjct: 489  LQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 521



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 39/180 (21%), Positives = 61/180 (33%), Gaps = 10/180 (5%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   + +D+G Y C+A    G      +LE  D    + P         + L    +A
Sbjct: 392  LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTA 451

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
              +C      DP   I W   G          T+ + G   L I   +  D+G Y C A 
Sbjct: 452  LLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVAT 507

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQ------PDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            +  GE    A ++    G    ++        P S  ++ ++          P TP   P
Sbjct: 508  SSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLP 567



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 4/90 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP   ++   N  +   G     C+    GDP   I W   G  F       T+ + G  
Sbjct: 432  PPPIILQGPANQTLAVDGTALLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG-- 487

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
             L I  +   D G YTC AT+  G  + +A
Sbjct: 488  TLQIKNLRISDTGTYTCVATSSSGETSWSA 517


>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
          Length = 1380

 Score =  121 bits (292), Expect = 6e-26
 Identities = 110/414 (26%), Positives = 171/414 (41%), Gaps = 48/414 (11%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI---KNSPDFQIHTFSTKS 4466
            PP   +      V + E      + +G P P I+WY++   +   K+ P        + S
Sbjct: 32   PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 91

Query: 4467 ILIIRQVFVE----DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            +  +R V       D   +  VA N  G A  S N  +E         ++   F     +
Sbjct: 92   LFFLRIVHGRRSKPDEGSYVCVARNYLGEA-VSRNASLEV-------ALLRDDFRQNPTD 143

Query: 4523 VNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            V V +G+   L+ +     P   +YW K+  KV+ D + + +   G   L+I      D+
Sbjct: 144  VVVAAGEPAILECQPPRGHPEPTIYWKKD--KVRIDDKEERISIRGG-KLMISNTRKSDA 200

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G Y CV  N  GE              +D    +      P  +  P+ +++V E +A+E
Sbjct: 201  GMYTCVGTNMVGE--------------RDSDPAELTVFERPTFLRRPI-NQVVLEEEAVE 245

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            F C++ G P PTV+W K D  +   +Y       D+YTLRI +    DEG Y C+A N  
Sbjct: 246  FRCQVQGDPQPTVRWKKDDADLPRGRY----DIKDDYTLRIKKTMSTDEGTYMCIAENRV 301

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-- 4759
            G++  +A L V  P Q    P     RD +V +G+   F  +     +P + W +EG+  
Sbjct: 302  GKMEASATLTVRAPPQFVVRP-----RDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQN 356

Query: 4760 -LIPETPD--FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L P  P              L I N    D G + C+A T AG +   A+L V
Sbjct: 357  LLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 410



 Score =  105 bits (252), Expect = 4e-21
 Identities = 110/383 (28%), Positives = 157/383 (40%), Gaps = 44/383 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   I +  + +I     K  L+I      D+ ++  V  N  G     
Sbjct: 161  GHPEPTIYWKKDKVRIDDKEE-RISIRGGK--LMISNTRKSDAGMYTCVGTNMVGERDSD 217

Query: 4496 -ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
             A L V E+          P+F     N  V   + V    +V G     V W K+   +
Sbjct: 218  PAELTVFER----------PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL 267

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R  I ++   YTL I +    D G Y C+A N  G+    A               
Sbjct: 268  -PRGRYDIKDD---YTLRIKKTMSTDEGTYMCIAENRVGKMEASA--------------- 308

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYFQM- 4671
             T    APP+ +   +D+IVA+G+ + F C+  G P P V W K     L+ P++  Q  
Sbjct: 309  -TLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPN 367

Query: 4672 SRTADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ--PDQADNLPALTPL 4727
            SR +   T  L I+     D G Y C A   AG +   A+L+VT    D+   +    P 
Sbjct: 368  SRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPA 427

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
               +  +G  A  K + T    P I WL+EG   P       I E     L I N    D
Sbjct: 428  NQTLAVDGT-ALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE--QGTLQIKNLRISD 484

Query: 4788 TGTFTCRATTAAGQVETSAKLVV 4810
            TGT+TC AT+++G+   SA L V
Sbjct: 485  TGTYTCVATSSSGETSWSAVLDV 507



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 87/350 (24%), Positives = 140/350 (40%), Gaps = 38/350 (10%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F ++     V E E   F  +  G+P P ++W +++  +        +       L I
Sbjct: 227  PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGR----YDIKDDYTLRI 282

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            ++    D   +  +AENR G  + SA L V            PP F +  ++  V  G+ 
Sbjct: 283  KKTMSTDEGTYMCIAENRVGKMEASATLTVR----------APPQFVVRPRDQIVAQGRT 332

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKV-----QPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            V    +  G     V+W K G +      QP   N       T  L I      D+G Y 
Sbjct: 333  VTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI 392

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLKDKIVAEGQAIEFSC 4644
            C A+  AG     A+  V+   T D+P         PP I++ P    +  +G A+   C
Sbjct: 393  CQALTVAGSILAKAQLEVTDVLT-DRP---------PPIILQGPANQTLAVDGTAL-LKC 441

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            K  G PLP + W K +    P +    +   ++ TL+I      D G Y CVA +S+G  
Sbjct: 442  KATGDPLPVISWLK-EGFTFPGRD-PRATIQEQGTLQIKNLRISDTGTYTCVATSSSGET 499

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
            + +A L VT+         ++   D+    G P++ +    +K   T+ W
Sbjct: 500  SWSAVLDVTESG-----ATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW 544



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 83/309 (26%), Positives = 129/309 (41%), Gaps = 35/309 (11%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-----PDIRNKILEEDG 4567
            PP       +V V+ G+   L+ K  G     + W K+G++V+     P     +L    
Sbjct: 32   PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 91

Query: 4568 TYTLLILEA--YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             + L I+       D G Y CVA N  GEA       VS  A+ +    +      P ++
Sbjct: 92   LFFLRIVHGRRSKPDEGSYVCVARNYLGEA-------VSRNASLEVALLRDDFRQNPTDV 144

Query: 4626 IEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
                   +VA G+     C+   G P PT+ W K DK+    K  ++S    +  L IS 
Sbjct: 145  -------VVAAGEPAILECQPPRGHPEPTIYW-KKDKVRIDDKEERISIRGGK--LMISN 194

Query: 4685 AFPEDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                D G Y CV  N  G R +  A+L V +       P      + VV E +  +F+ Q
Sbjct: 195  TRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPI-----NQVVLEEEAVEFRCQ 249

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            +    +PT++W ++ A +P           ++  L I  T   D GT+ C A    G++E
Sbjct: 250  VQGDPQPTVRWKKDDADLPR----GRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKME 305

Query: 4804 TSAKLVVKS 4812
             SA L V++
Sbjct: 306  ASATLTVRA 314



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 81/317 (25%), Positives = 125/317 (39%), Gaps = 41/317 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+I + P +  + +G       +  G P P + W+K+G+R+                  
Sbjct: 32  PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERV------------------ 73

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-SYVQDQRSQYITDTQQRETEERI 383
              T K D   + +L  + +   +   +     P E SYV   R+ Y+ +   R     +
Sbjct: 74  --ETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARN-YLGEAVSRNASLEV 130

Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILV 442
            +    L   F +   D  V  G+    +C+   G P P + W   D+   DD   +I +
Sbjct: 131 AL----LRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWK-KDKVRIDDKEERISI 185

Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGE-TAFQCRLNVIEKEQVVAPKFVERFSTLN 501
                  LMI+N   SD+G+ TCV  N  GE  +    L V E+     P F+ R     
Sbjct: 186 RGG---KLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFER-----PTFLRRPINQV 237

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V E E V    +  G P P + W+KD    +P     I  D    TL I +  ++D   Y
Sbjct: 238 VLEEEAVEFRCQVQGDPQPTVRWKKDDAD-LPRGRYDIKDD---YTLRIKKTMSTDEGTY 293

Query: 562 QCTAQNVAGSTATRARL 578
            C A+N  G     A L
Sbjct: 294 MCIAENRVGKMEASATL 310



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 13/193 (6%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR----DDYNHKI 440
           + ++   P+ V+   D  V++G+ T  +C+  GRP P + W+ +  ++     D  +H++
Sbjct: 26  LRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRM 85

Query: 441 LVNESGNHALMITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498
           L+       L I +   S  D G   CVARN  GE   +   N   +  ++   F +  +
Sbjct: 86  LLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR---NASLEVALLRDDFRQNPT 142

Query: 499 TLNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            + V  GEP +L  +   G P P I W+KD V  I + E RI   GG   L I   + SD
Sbjct: 143 DVVVAAGEPAILECQPPRGHPEPTIYWKKDKVR-IDDKEERISIRGG--KLMISNTRKSD 199

Query: 558 AAWYQCTAQNVAG 570
           A  Y C   N+ G
Sbjct: 200 AGMYTCVGTNMVG 212



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 96/404 (23%), Positives = 163/404 (40%), Gaps = 51/404 (12%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P + W + K   V  +    R + + G   L+I      D G YTC   N  GE 
Sbjct: 160 RGHPEPTIYWKKDK---VRIDDKEERISIRGG--KLMISNTRKSDAGMYTCVGTNMVGE- 213

Query: 156 ICSVYIQPEGXXXXXXXXXXXXXYRHVSETV-EHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                 +                 R +++ V E +A   +       + T +    +   
Sbjct: 214 ------RDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL 267

Query: 215 HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
                D K D +  R+ + +S  E  T   + E+ V    E   +L   +PP+   +PR+
Sbjct: 268 PRGRYDIK-DDYTLRIKKTMSTDEG-TYMCIAENRVG-KMEASATLTVRAPPQFVVRPRD 324

Query: 275 SKLQEGADAQFQVQLSGNPRPRVTWFKNG-QRLINSNKHEIITTHNHTT----LRVRNTQ 329
             + +G    F  +  GNP+P V W K G Q L+  N+ +   +    +    L + N Q
Sbjct: 325 QIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQ 384

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKA 389
           +SD+G+Y   A      +  +G +  ++  E          +TD     T+    I  + 
Sbjct: 385 RSDAGYYICQA------LTVAGSILAKAQLE----------VTDVL---TDRPPPIILQG 425

Query: 390 LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
            A Q + V    D T        C+ TG P P ++W + +       + +  + E G   
Sbjct: 426 PANQTLAV----DGT----ALLKCKATGDPLPVISW-LKEGFTFPGRDPRATIQEQGT-- 474

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
           L I N+ +SD+G  TCVA + SGET++   L+V E    ++  +
Sbjct: 475 LQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNY 518



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 57/193 (29%), Positives = 84/193 (43%), Gaps = 17/193 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
           P F++   ++ V E +   F C+V G P P V W  +D  + R  Y+ K       ++ L
Sbjct: 227 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIK------DDYTL 280

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I     +D G   C+A N+ G+      L V        P+FV R     V +G  V  
Sbjct: 281 RIKKTMSTDEGTYMCIAENRVGKMEASATLTV-----RAPPQFVVRPRDQIVAQGRTVTF 335

Query: 511 NARAVGTPTPRITWQKDGVP--IIPNPELRIHTDGGAS---TLDIPRAKASDAAWYQCTA 565
                G P P + WQK+G    + PN   + ++    S    L I   + SDA +Y C A
Sbjct: 336 PCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQA 395

Query: 566 QNVAGSTATRARL 578
             VAGS   +A+L
Sbjct: 396 LTVAGSILAKAQL 408



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 55/195 (28%), Positives = 82/195 (42%), Gaps = 13/195 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ------IRDDYNHKILVNES 445
           PQFV   +D+ V +G+   F C   G P P V W     Q           N +  V+ +
Sbjct: 316 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 375

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVRE 504
           G+  L ITN+  SD+G   C A   +G    + +L V +       P  ++  +   +  
Sbjct: 376 GD--LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAV 433

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
               +L  +A G P P I+W K+G      +P   I   G   TL I   + SD   Y C
Sbjct: 434 DGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG---TLQIKNLRISDTGTYTC 490

Query: 564 TAQNVAGSTATRARL 578
            A + +G T+  A L
Sbjct: 491 VATSSSGETSWSAVL 505



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 70/293 (23%), Positives = 118/293 (40%), Gaps = 24/293 (8%)

Query: 90  KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149
           +F  +++G+P P V W +  A L    +Y ++      D +L IK+    DEG Y C A 
Sbjct: 245 EFRCQVQGDPQPTVRWKKDDADLPR-GRYDIK-----DDYTLRIKKTMSTDEGTYMCIAE 298

Query: 150 NQYG--EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKV 207
           N+ G  EA  ++ ++                 R V+   E K    Q     Q   +Q +
Sbjct: 299 NRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKG-NPQPAVFWQKEGSQNL 357

Query: 208 AYTNGTDH-------SSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSL 260
            + N           S T D  +   + R        +++T    G    +   E+   L
Sbjct: 358 LFPNQPQQPNSRCSVSPTGDLTITNIQ-RSDAGYYICQALT--VAGSILAKAQLEVTDVL 414

Query: 261 GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
               PP I Q P N  L     A  + + +G+P P ++W K G       +    T    
Sbjct: 415 TDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEG--FTFPGRDPRATIQEQ 472

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            TL+++N + SD+G YT +A + +G    + + AV   TES     ++  ++D
Sbjct: 473 GTLQIKNLRISDTGTYTCVATSSSG---ETSWSAVLDVTESGATISKNYDLSD 522



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 7/98 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-----IPNPELRI 539
           +++   P+ VE  S + V +GEP  LN +A G PTP I W KDG  +      P     +
Sbjct: 27  RQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRML 86

Query: 540 HTDGGASTLDIPRAKAS--DAAWYQCTAQNVAGSTATR 575
              G    L I   + S  D   Y C A+N  G   +R
Sbjct: 87  LPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR 124



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 7/104 (6%)

Query: 635 PPPQFIV-PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
           PPP  +  P     A++G  +    + +  GDP   I WLK G +        +I   G 
Sbjct: 418 PPPIILQGPANQTLAVDGTAL---LKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG- 473

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR-ATIER 736
            +L + +L I D+G YTC A S++G     AVL VT   ATI +
Sbjct: 474 -TLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISK 516



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
            D+   E  V   P F+ +  +  V E E V F C+V+   DP+  + W ++   LP G R
Sbjct: 215  DSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQ--GDPQPTVRWKKDDADLPRG-R 271

Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
            Y    D    +L I    + D G Y+C A N  G+    AT++ +  P  +++
Sbjct: 272  YDIKDD---YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVR 321



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 18/168 (10%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            +RP FL    +   L+E +   F C+V+   DP  T+ W  +   +  G RY    D+  
Sbjct: 225  ERPTFLRRPINQVVLEE-EAVEFRCQVQ--GDPQPTVRWKKDDADLPRG-RYDIKDDY-- 278

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226
              L I  T + D GTYMC A N++G+   + TL V      ++  +         Q+ AQ
Sbjct: 279  -TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRD--------QIVAQ 329

Query: 2227 GHSTRIEVEEPKISPPRFVTELRGTTHVF---EGKTAHFECQVEPVHD 2271
            G +     E      P    +  G+ ++    + +  +  C V P  D
Sbjct: 330  GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD 377



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 56/237 (23%), Positives = 81/237 (34%), Gaps = 14/237 (5%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN-----FPIKNSPDFQIHTFST 4464
            PP F  + +   V +     F  E  G P P + W +E      FP +        + S 
Sbjct: 315  PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 374

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
               L I  +   D+  +   A    G+    A L V +          PP       N  
Sbjct: 375  TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDR----PPPIILQGPANQT 430

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            +       L  K TG     + WLK G           ++E G  TL I      D+G Y
Sbjct: 431  LAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTY 488

Query: 4585 ECVAINSAGEARCDAEC-VVSLPATKDKPKPQTKAANAP--PEIIEPLKDKIVAEGQ 4638
             CVA +S+GE    A   V    AT  K    +     P  P++ +  K+ +    Q
Sbjct: 489  TCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQ 545



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 7/113 (6%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
            + +D  + +V  +P F+ RP + + V+E + V F C+++   D    V W K+   +  G
Sbjct: 214  RDSDPAELTVFERPTFLRRPIN-QVVLEEEAVEFRCQVQG--DPQPTVRWKKDDADLPRG 270

Query: 1491 HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
             R+    D+    L I   ++ D G Y C A N VG  E S  LT R+    V
Sbjct: 271  -RYDIKDDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFV 319



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 7/84 (8%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            +N +V +E + + F C V+    PT  + W  ++  LP G RY    D+   +L I  T 
Sbjct: 234  INQVVLEE-EAVEFRCQVQGDPQPT--VRWKKDDADLPRG-RYDIKDDY---TLRIKKTM 286

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
              D G Y C A N  G    S +L
Sbjct: 287  STDEGTYMCIAENRVGKMEASATL 310



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 19/140 (13%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I  T +TD GTY C A N+ G+ E S  L     +    P+F    ++ + +  G++ 
Sbjct: 280  LRIKKTMSTDEGTYMCIAENRVGKMEASATL-----TVRAPPQFVVRPRD-QIVAQGRTV 333

Query: 3168 HFECTVVPVDDPDMKIEWYHNG--------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
             F C      +P   + W   G        QP + ++R  +VS  G   L I   Q  D+
Sbjct: 334  TFPCET--KGNPQPAVFWQKEGSQNLLFPNQPQQPNSRC-SVSPTG--DLTITNIQRSDA 388

Query: 3220 GEYVCRAYNKYGEDFTRATI 3239
            G Y+C+A    G    +A +
Sbjct: 389  GYYICQALTVAGSILAKAQL 408



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PPI  Q   N   A  G A  + K  G+P PV+SW ++       +  +    + T    
Sbjct: 419 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT---- 474

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L IK +   D G YTC A +  GE   S  +
Sbjct: 475 LQIKNLRISDTGTYTCVATSSSGETSWSAVL 505



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 11/132 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I  T+ +D+G Y+C  TN  G+ +     +  + +  ++P F     N   L++ ++ 
Sbjct: 190  LMISNTRKSDAGMYTCVGTNMVGERD----SDPAELTVFERPTFLRRPINQVVLEE-EAV 244

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             F C V    DP   + W  +   +    R     D+    L I  T + D G Y+C A 
Sbjct: 245  EFRCQV--QGDPQPTVRWKKDDADLPRG-RYDIKDDY---TLRIKKTMSTDEGTYMCIAE 298

Query: 3228 NKYGEDFTRATI 3239
            N+ G+    AT+
Sbjct: 299  NRVGKMEASATL 310



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   + WL+ G      +   T+ + G   L +K +   D+GTYTC A +  GE   S
Sbjct: 445  GDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSWS 502

Query: 1798 STLFV 1802
            + L V
Sbjct: 503  AVLDV 507



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)

Query: 1834 EDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
            +  E+ V + P F+ +      L E ++  + C+++  P P +R  W  +   L  G RY
Sbjct: 217  DPAELTVFERPTFLRRPINQVVLEE-EAVEFRCQVQGDPQPTVR--WKKDDADLPRG-RY 272

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
               +D+    L I      D G Y C A N +G+  +S  L V++    +
Sbjct: 273  DIKDDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFV 319



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 7/95 (7%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT- 126
           E  PP   +   +   ++G       K  G PTP + W  K    VE +K   R +    
Sbjct: 29  EDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWY-KDGERVETDKDDPRSHRMLL 87

Query: 127 GDVSLLIKQIGPG-----DEGEYTCTARNQYGEAI 156
              SL   +I  G     DEG Y C ARN  GEA+
Sbjct: 88  PSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV 122



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 6/107 (5%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++TV + P F R   N   +E   V   C++Q  GD    V W  +   +  G   R   
Sbjct: 220  ELTVFERPTFLRRPINQVVLEEEAVEFRCQVQ--GDPQPTVRWKKDDADLPRG---RYDI 274

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
            + DY  L +      D G Y C A N++G+   S  L V A    ++
Sbjct: 275  KDDYT-LRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVV 320



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TGD   VI W   G T        T+   G   L+I   + +D+GTY+C AT+  G+   
Sbjct: 444  TGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSW 501

Query: 3135 SVKLECVD 3142
            S  L+  +
Sbjct: 502  SAVLDVTE 509



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 8/99 (8%)

Query: 1707 ITQAPVFTM-PMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + P F   P+  + V E +A  F  ++   GDP+  V W ++   +    R     D+
Sbjct: 223  VFERPTFLRRPINQV-VLEEEAVEFRCQV--QGDPQPTVRWKKDDADLPRG-RYDIKDDY 278

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
                L +K     D GTY C A N +G+   S+TL V++
Sbjct: 279  ---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA 314



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DP   I W K G T   G   ++T      TL I +LR  D+G YTC AT+  GE   +A
Sbjct: 446  DPLPVISWLKEGFTFP-GRDPRATIQ-EQGTLQIKNLRISDTGTYTCVATSSSGETSWSA 503

Query: 2731 SIKIED 2736
             + + +
Sbjct: 504  VLDVTE 509



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/72 (38%), Positives = 35/72 (48%), Gaps = 8/72 (11%)

Query: 800 PTMRVEWYKDGRPITAS-----SRITSIFNFGYVSLNIMHLRAE--DAGSYTVRAVNKLG 852
           PT  +EWYKDG  +        S    + +     L I+H R    D GSY   A N LG
Sbjct: 60  PTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLG 119

Query: 853 EAIS-TASIRVA 863
           EA+S  AS+ VA
Sbjct: 120 EAVSRNASLEVA 131



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 16/117 (13%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK---LLPSGHRYR--- 3879
            V  PP+F+ + +   V +   V F C  E K +P+  + W + G    L P+  +     
Sbjct: 312  VRAPPQFVVRPRDQIVAQGRTVTFPC--ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSR 369

Query: 3880 -TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL-----PDIILQ 3930
             +V   G   L I  +   D+G YIC+A+   G    KA +    +     P IILQ
Sbjct: 370  CSVSPTG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQ 424



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 5/124 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD    + WLK+G          T    G   L IK++ + D G YTC A ++ G+ + S
Sbjct: 445  GDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSWS 502

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIV 1056
            A L +      I+++     L  +       + +  T+  V ++ +P   G L  +  I+
Sbjct: 503  AVLDVTESGATISKNY---DLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYII 559

Query: 1057 EGQS 1060
            E  S
Sbjct: 560  EAFS 563



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 7/100 (7%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ + ++P FL   +  N++V  + A  E R + Q D   TV W  +   +    R    
Sbjct: 220  ELTVFERPTFLR--RPINQVVLEEEA-VEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIK 275

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             D+    L I    + D G Y  +A N  G+ + SA++TV
Sbjct: 276  DDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 312



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/77 (28%), Positives = 31/77 (40%)

Query: 4073 YDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCC 4132
            Y  ++ K M + E      A  +V   +       R PP FV  P    V +G    F C
Sbjct: 278  YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPC 337

Query: 4133 RVTGHPKPRVMWLLNGN 4149
               G+P+P V W   G+
Sbjct: 338  ETKGNPQPAVFWQKEGS 354



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 11/107 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTL--- 3747
            PPR  VE   ++ V +G P   +C+ E  G PT  I+W+ +G    T     R H +   
Sbjct: 32   PPRI-VEHPSDVIVSKGEPTTLNCKAE--GRPTPTIEWYKDGERVETDKDDPRSHRMLLP 88

Query: 3748 -NDFGFIALDIDYIYARDAGEYTCRATNKWGSATT-TAKITCSAKRD 3792
                 F+ +        D G Y C A N  G A +  A +  +  RD
Sbjct: 89   SGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD 135



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 4/69 (5%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   LE Q  PR  P   I W K+ V +      + +   G   L I++ R  D+G+YT
Sbjct: 149  GEPAILECQ-PPRGHPEPTIYWKKDKVRIDDKEE-RISIRGG--KLMISNTRKSDAGMYT 204

Query: 2717 CKATNLLGE 2725
            C  TN++GE
Sbjct: 205  CVGTNMVGE 213



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 6/103 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   P + ++ E  +  F C++    D    V W  +   L  G R    +D+    L
Sbjct: 227  PTFLRRPINQVVLEEEAVEFRCQV--QGDPQPTVRWKKDDADLPRG-RYDIKDDY---TL 280

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             I      D G Y C A NR G+   S  L V+     ++ P+
Sbjct: 281  RIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPR 323



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 3/68 (4%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIP 4170
            P F+  P    V E E   F C+V G P+P V W  +   +  G RY +  D  Y   I 
Sbjct: 227  PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDD--YTLRIK 283

Query: 4171 KTRQYDTG 4178
            KT   D G
Sbjct: 284  KTMSTDEG 291



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 13/105 (12%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASSR 684
           V  PPQF+V  +     +G  + F    E  G+P   + W K G        Q  + +SR
Sbjct: 312 VRAPPQFVVRPRDQIVAQGRTVTFPC--ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSR 369

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             S+   G   L + ++   D+G Y C+A++  G    KA L VT
Sbjct: 370 -CSVSPTG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVT 411



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 12/133 (9%)

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Y R +   +     P  I +      +S+G+     C+ E  P P   +EWY +G+ +++
Sbjct: 18   YVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPT--IEWYKDGERVET 75

Query: 1890 GHRYRTSNDFGFAALDIL---TVYGE----DSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
                  S+     +  +     V+G     D G Y C A N LG+AVS    N   + ++
Sbjct: 76   DKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR---NASLEVAL 132

Query: 1943 IRDSQHESALEKI 1955
            +RD   ++  + +
Sbjct: 133  LRDDFRQNPTDVV 145



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V E+P F +   N  V E   V     +    DP   V W  +   + +G R+    D+ 
Sbjct: 223  VFERPTFLRRPINQVVLEEEAVEFRCQVQ--GDPQPTVRWKKDDADLPRG-RYDIKDDY- 278

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
               L I    + D GTYMC A N VG+   ++++ V A
Sbjct: 279  --TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA 314



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 2505 FEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG 2564
            FE+P F   L  P      +    E R    GDP     W  +  +L  G R+    D+ 
Sbjct: 224  FERPTF---LRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDDY- 278

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAG 2590
              TL I   ++ D G YMC A NR G
Sbjct: 279  --TLRIKKTMSTDEGTYMCIAENRVG 302



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 12/112 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL------PSGHRYRTVY 3882
            PP+ +       V + E     C+ E +  P   IEWY++G+ +      P  HR     
Sbjct: 32   PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPT--IEWYKDGERVETDKDDPRSHRMLLPS 89

Query: 3883 DMGFVSLDILYVYAE--DSGEYICRAVNDFGEDFTK-ATISCKKLPDIILQN 3931
               F  L I++      D G Y+C A N  GE  ++ A++    L D   QN
Sbjct: 90   GSLFF-LRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQN 140



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLR------- 2708
            +G+   L  + E R  P   IEW+K+G  + T      +    L + S+  LR       
Sbjct: 46   KGEPTTLNCKAEGRPTPT--IEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 103

Query: 2709 NDDSGIYTCKATNLLGEAVS-TASIKI 2734
              D G Y C A N LGEAVS  AS+++
Sbjct: 104  KPDEGSYVCVARNYLGEAVSRNASLEV 130



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-----MTISHVR 2442
            + +G+    +C+    G PT  +EW+++ + +E      ++H     S     + I H R
Sbjct: 44   VSKGEPTTLNCKA--EGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 101

Query: 2443 DE--DEGVYMCRASNLLGE 2459
                DEG Y+C A N LGE
Sbjct: 102  RSKPDEGSYVCVARNYLGE 120



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P++  L+ + +A  +C+     D    + W   G          TI + G   
Sbjct: 419  PPIILQGPANQTLAVDGTALLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG--T 474

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L+I  +   D G YTC AT+  GE + S  L V
Sbjct: 475  LQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 507



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 39/180 (21%), Positives = 61/180 (33%), Gaps = 10/180 (5%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   + +D+G Y C+A    G      +LE  D    + P         + L    +A
Sbjct: 378  LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTA 437

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
              +C      DP   I W   G          T+ + G   L I   +  D+G Y C A 
Sbjct: 438  LLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVAT 493

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQ------PDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            +  GE    A ++    G    ++        P S  ++ ++          P TP   P
Sbjct: 494  SSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLP 553



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 4/90 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP   ++   N  +   G     C+    GDP   I W   G  F       T+ + G  
Sbjct: 418  PPPIILQGPANQTLAVDGTALLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG-- 473

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
             L I  +   D G YTC AT+  G  + +A
Sbjct: 474  TLQIKNLRISDTGTYTCVATSSSGETSWSA 503


>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
          Length = 4650

 Score =  121 bits (291), Expect = 7e-26
 Identities = 89/309 (28%), Positives = 139/309 (44%), Gaps = 13/309 (4%)

Query: 278  QEGADAQFQVQLSG-NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +EG   ++  ++   +   +VTW+   ++L NS K+EI        L V++  K D G Y
Sbjct: 2807 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
                 N  G   +   L V+   E Y  D   +      +R T+  + + E+   P+F  
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREVY--DYYCRRTMKKIKRRTDT-MRLLERP--PEFTL 2921

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES--GNHALMITN 454
               ++    G+  RF   +T  P P VTW+ + ++I+   N K    ES  G + L I +
Sbjct: 2922 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 2981

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVI----EKEQVVAPKFVERFSTLNVREGEPVVL 510
            VT  D    T VARNK GE + + +L V       +  + P F    +    +EG+ V  
Sbjct: 2982 VTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCF 3041

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDG-GASTLDIPRAKASDAAWYQCTAQNVA 569
              R  G P P + W+KDG P+   P + I  +G     L I      D  +Y+ TA N A
Sbjct: 3042 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTA 3101

Query: 570  GSTATRARL 578
            GST+ +A L
Sbjct: 3102 GSTSCQAHL 3110



 Score =  116 bits (279), Expect = 2e-24
 Identities = 158/722 (21%), Positives = 282/722 (39%), Gaps = 63/722 (8%)

Query: 3807 KIKELERGRISDAPKEEPIVST-PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            K   LE   + +      I +T   + +T+ +S TV E E  RF C  + +  P   + W
Sbjct: 3764 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPT--VTW 3821

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             R G++L +  R++        + +I  V A D G Y     N  G+   + T++ +K  
Sbjct: 3822 LRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 3881

Query: 3926 DIILQNQVPRGMKRSEALTQMEATIKK----------YTSEVYLTEDDLYDVDKKQ---- 3971
                    P  +K  E   +    +K           +   V  TE     ++K Q    
Sbjct: 3882 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPIEKVQHLPV 3941

Query: 3972 --PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF- 4028
              PP+    ++++ S    E  K  C +        +V W+ +GK L     F   Y   
Sbjct: 3942 SAPPKITQFLKAEAS---KEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 3998

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD-SQLPKHMKSIEKI 4087
            G   +    +   D GEY+C  +   G  +T           I    S++ +  KS +K 
Sbjct: 3999 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 4058

Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
             E   + +  P+    E  +  P +   L D  TV     A+F  + TG P+P  +W  +
Sbjct: 4059 TESTVTRKTEPK--APEPISSKPVIVTGLQDT-TVSSDSVAKFAVKATGEPRPTAIWTKD 4115

Query: 4148 GNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDY 4206
            G  I  G +YKL+ D G +  +I KT   D+G                  L +    D  
Sbjct: 4116 GKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD-- 4173

Query: 4207 RGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQ 4266
                           T+ Q+  T  +KT E     Q++ V+  + E+  K ++  E +  
Sbjct: 4174 ---------------TEAQKVST--QKTSEITP--QKKAVV--QEEISQKALRSEEIKMS 4212

Query: 4267 QSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNL 4326
            ++  ++K        + L +E+V K +    ++ + +I  +++T  + A    + + +  
Sbjct: 4213 EAKSQEKLALKEEASKVLISEEVKKSA---ATSLEKSIVHEEITKTSQASEEVRTHAEIK 4269

Query: 4327 DQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVG-DKEITRKITST 4385
              + +++    Q+ V  K  I   ++       V +   ++ +  V G D+ +T K  S 
Sbjct: 4270 AFSTQMSINEGQRLVL-KANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASH 4328

Query: 4386 ETTEI-EHKAQTQERVVEGPV------KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438
                I    ++T+E +V+         + S  P F  + +   + E +   F  E  GEP
Sbjct: 4329 RDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTREISGEP 4388

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
             P I+W++ N PI  S +  I        L IR   V DS  +   A+N  G    +A+L
Sbjct: 4389 SPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 4448

Query: 4499 VV 4500
            +V
Sbjct: 4449 MV 4450



 Score =  109 bits (262), Expect = 2e-22
 Identities = 86/289 (29%), Positives = 125/289 (43%), Gaps = 24/289 (8%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            V W    ++++   + +I  EDG   L + +    D G Y C  +N  GE    AE  V 
Sbjct: 2827 VTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVK 2886

Query: 4605 ---------LPATKDKPKPQT---KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
                        T  K K +T   +    PPE   PL +K    G+ + F   I   P P
Sbjct: 2887 GVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEP 2946

Query: 4653 TVQWYKGDKLIKP---SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
             V WYK  + IKP    K +        Y L I+    +D+ +Y  VA N  G  +  AK
Sbjct: 2947 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 3006

Query: 4710 LKVT-QPDQADNLPALTP-----LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
            L VT  P   D+   L P     L +    EGQ   F+ +++    PT++W ++G  +  
Sbjct: 3007 LTVTLHPPPTDS--TLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSL 3064

Query: 4764 TPDFQMIHEG-NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             P+ ++IHEG +   L I +T  EDTG +   AT  AG     A L V+
Sbjct: 3065 GPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 3113



 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 142/664 (21%), Positives = 263/664 (39%), Gaps = 57/664 (8%)

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +G+SA F C      +P   + W   G+ +  S R +  +       +I+  Q  D G Y
Sbjct: 3801 EGESARFSCDTD--GEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 3858

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESL-------QPDSLAKIRE-LESLQGAQQQTP 3274
                 N  G+     T+    K  V  +++        P+   K  E ++S +  +   P
Sbjct: 3859 SVVVENSEGKQEAEFTLTIQ-KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEP 3917

Query: 3275 STPSAEPPKF-----ITQIQD--------VTKLVEGQSAHFEARLVPVDDPDL----KVE 3317
            S P A  P       I ++Q         +T+ ++ +++   A+L  V +  +    +V 
Sbjct: 3918 SHPKAVSPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVT 3977

Query: 3318 WFYNGKKLP-HGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
            W+ +GKKL  +GH    +   G   L I    E + GEY C  + + G  ++K NL+   
Sbjct: 3978 WYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGG--TSKTNLQFMG 4035

Query: 3377 KENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGE 3436
            +    +  ++ +  E      +T E ++ R+ +    E     PV    L +   +    
Sbjct: 4036 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT-TVSSDS 4094

Query: 3437 NAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCR 3496
             A F  + T   +P     W  +GK++  G +++   D G   LEI  T   DSG Y C 
Sbjct: 4095 VAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCT 4152

Query: 3497 AYNNYGEAVTTASMKVQGKRNIILES-QLPKGMEGTIDKIAALEGYSG-----TVDTLTP 3550
              N+ G   ++  + ++  ++   +     K  E T  K A ++         + +    
Sbjct: 4153 VKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS 4212

Query: 3551 EAESGNPPEFTTTPSDLILSE----NSSAHFECRLI--PVNDSSMRVEWFHNGKPLLTGS 3604
            EA+S          S +++SE    +++   E  ++   +  +S   E       +   S
Sbjct: 4213 EAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS 4272

Query: 3605 RVKTINDFGFVILE--IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662
               +IN+   ++L+  I G       L   + TN     +   +  V G    +   Q  
Sbjct: 4273 TQMSINEGQRLVLKANIAGATDVKWVLNGVELTN-----SEEYRYGVSGSDQTLTIKQAS 4327

Query: 3663 SHFKSGTESIQKLEETLHK-REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEP 3721
               +     I K +E + K + ++T+  E  + P F  + +   ++ EG  V F   +  
Sbjct: 4328 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQ-NINEGQNVLFTREIS- 4385

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
             G+P+  I+WF N  P +  S V         +L+I      D+G+YT +A N  G  + 
Sbjct: 4386 -GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSA 4444

Query: 3782 TAKI 3785
            TA +
Sbjct: 4445 TASL 4448



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 93/361 (25%), Positives = 145/361 (40%), Gaps = 49/361 (13%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P+  Q++    E  EG H  Y  ++    D S +  WY    +L+   ++  T++ G   
Sbjct: 2796 PVSGQIMHAVGE--EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAI 2852

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L +  +   D G Y CK +N  G               + D   R  + ++I+ +   M 
Sbjct: 2853 LYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCR-RTMKKIKRRTDTMR 2911

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                      +++ P FT  L +    V G++V     +    +P+  + W+K+G  +  
Sbjct: 2912 L---------LERPPEFTLPLYNKTAYV-GENVRFGVTITVHPEPH--VTWYKSGQKIKP 2959

Query: 2688 GAR-LKSTF--DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
            G    K TF  D GL  L+INS+  DD   YT  A N  GE    A + +         +
Sbjct: 2960 GDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV---------T 3010

Query: 2745 LHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPT 2804
            LHP   D                       +F   L N  C+EG ++ FE  V     PT
Sbjct: 3011 LHPPPTD------------------STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPT 3052

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHD-FSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            LK  W  + +PL  G   +  H+   Y +L I  T  ED+G Y   ATN+ GS +    L
Sbjct: 3053 LK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHL 3110

Query: 2864 R 2864
            +
Sbjct: 3111 Q 3111



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 93/345 (26%), Positives = 136/345 (39%), Gaps = 41/345 (11%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG    Y C+IE Y D + +V WYF  + L++  +Y  + + G A L +  +   D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK 1977
             CK +N+ G+  S   L V+    +  D      ++KI+   D  R          +   
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREVY-DYYCRRTMKKIKRRTDTMR---------LLERP 2916

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F  P+ N     G  V    T+T   +P   V WY +G+ ++ G              
Sbjct: 2917 PEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDN------------ 2962

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
            D  Y +  D G Y     +   +     +V    K G       E   K   +L     P
Sbjct: 2963 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG-------EDSCK--AKLTVTLHP 3013

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
             P +      RP+F   L + E  +EG    FE RV  I  P  T+ W  +GQ +  G  
Sbjct: 3014 PPTDST---LRPMFKRLLANAE-CQEGQSVCFEIRVSGIPPP--TLKWEKDGQPLSLGPN 3067

Query: 2158 YRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                H+   Y AL I  T  ED+G Y   ATN  G       L+V
Sbjct: 3068 IEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 3112



 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 147/718 (20%), Positives = 272/718 (37%), Gaps = 57/718 (7%)

Query: 1132 SMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
            S   ETR S+ +         K+  +EE K +E      +I  +    +        V E
Sbjct: 3743 SQMTETRESLSSYEHSASAEMKSAALEE-KSLEEKSTTRKIKTTLAARILTKPRSMTVYE 3801

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G++    C  +  G+P   V W   GR ++  +R +          +I    ++D G Y+
Sbjct: 3802 GESARFSCDTD--GEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYS 3859

Query: 1252 VRAVNHLGSAH---TSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVR------ 1302
            V   N  G      T  I +       VT     ++ E      +A +  K+V+      
Sbjct: 3860 VVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSH 3919

Query: 1303 -----------------EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVE 1345
                             + + V   P+ ++ L    + E     L C ++    +   V 
Sbjct: 3920 PKAVSPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAK--LTCVVESSVLRAKEVT 3977

Query: 1346 WFCNGKPIKTGHRFRPAYEFDYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            W+ +GK +K    F+  Y  D    L + ++   D G Y C+ + + G + T+      A
Sbjct: 3978 WYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQA 4037

Query: 1405 KKDLILESQHPSGLEKIQY--LEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHV 1462
             K +  +    S  +K      E T   K      E ++ KP  VT    +++       
Sbjct: 4038 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVT---GLQDTTVSSDS 4094

Query: 1463 HFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAV 1522
              +  ++   +      W K+G+ +T G +++   D G   L+I      DSG+YTC   
Sbjct: 4095 VAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK 4154

Query: 1523 NLVGTDEVSCRLTCRSTTDIVR---STQNEAGL---EQIQVLEDRS-KYHRTDMV--DEV 1573
            N  G+   SC+LT ++  D      STQ  + +   ++  V E+ S K  R++ +   E 
Sbjct: 4155 NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEA 4214

Query: 1574 TTQAPI-----CTTSLKNVEIKEGQRAHFERRLI--PVSDATLKVEWYHNNKPLKSGSRF 1626
             +Q  +      +  L + E+K+      E+ ++   ++  +   E    +  +K+ S  
Sbjct: 4215 KSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQ 4274

Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLES-QHEGAL 1685
               N    + L        D             E    G++      +I   S + EG L
Sbjct: 4275 MSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGIL 4334

Query: 1686 PRLNQL-EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRV 1744
              +++  E   K Q      + ++ AP F    +   + E Q   F   +   G+P   +
Sbjct: 4335 TCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTREI--SGEPSPEI 4392

Query: 1745 EWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            EW +N +PI  S+ ++        +L ++  +  DSG YT +A N  G+   +++L V
Sbjct: 4393 EWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 4450



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 68/206 (33%), Positives = 91/206 (44%), Gaps = 15/206 (7%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK--ILEED-GTY 4569
            PP FTL   N     G+ VR    +T      V W K+G+K++P   +K    E D G Y
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 2975

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL--PATKDKPKPQTKAANAPPEIIE 4627
             L I      D  +Y  VA N  GE  C A+  V+L  P T    +P  K   A  E   
Sbjct: 2976 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAE--- 3032

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAF 4686
                    EGQ++ F  ++ G P PT++W K G  L        +    D Y L I +  
Sbjct: 3033 ------CQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTL 3086

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            PED G Y+  A N+AG  +  A L+V
Sbjct: 3087 PEDTGYYRVTATNTAGSTSCQAHLQV 3112



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 97/434 (22%), Positives = 182/434 (41%), Gaps = 40/434 (9%)

Query: 1005 KDIIAESQHPGGLE-KIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF 1063
            ++ ++  +H    E K   LE+ S   K T  ++K T   R L   +    + EG+SA F
Sbjct: 3749 RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMT-VYEGESARF 3807

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNA 1123
                +   +   TV W   G+ ++++ R Q          +I+SV+A D G Y+VV  N+
Sbjct: 3808 SC--DTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 3865

Query: 1124 AGEAQLSASMTVE----TRSSIDTSSIHRGLYEKTRHIE------ESKFVEPMY-QIEEI 1172
             G+ +   ++T++    T  ++ +    +    + +  E        K  EP + +    
Sbjct: 3866 EGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSP 3925

Query: 1173 SKSKPVFVQ-----PLSNPPPVSE------GKNI-HLECRLEPMGDPTMRVEWFHNGRSV 1220
            +++KP  ++     P+S PP +++       K I  L C +E        V W+ +G+ +
Sbjct: 3926 TETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL 3985

Query: 1221 TVGSRFKTYYDF-GFVALDIIHATSADTGEYTVRAVNHLGSAHTS------AIVRVIERS 1273
                 F+ +Y   G   L I + T +D GEY        G++ T+      A   + E+ 
Sbjct: 3986 KENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKV 4045

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
              +++T+        +  E    R  + +    +   P     L +  TV   +V  +  
Sbjct: 4046 SKISETKKSDQ----KTTESTVTRKTEPKAPEPISSKPVIVTGLQD-TTVSSDSV-AKFA 4099

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            ++  G+      W  +GK I  G +++ + +     L++      DSG+YTC   N  G 
Sbjct: 4100 VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGS 4159

Query: 1394 AVTSCALRVIAKKD 1407
              +SC L + A KD
Sbjct: 4160 VSSSCKLTIKAIKD 4173



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 105/457 (22%), Positives = 180/457 (39%), Gaps = 38/457 (8%)

Query: 1774 YVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRR 1833
            Y  P    T    A + + E  +  T   +++ SL       SA  K   LE+ S  ++ 
Sbjct: 3721 YAVPSFKKTSEMEASSSVREVKSQMT---ETRESLSSYEHSASAEMKSAALEEKSLEEKS 3777

Query: 1834 EDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
               ++    A R +T+    T + EG+SA + C  +  P P   V W   G+VL +  R+
Sbjct: 3778 TTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPT--VTWLRKGRVLSTSARH 3834

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE-------SIIRDS 1946
            + +     +  +I +V   D G Y+    N+ G+  +   L +Q          S  R  
Sbjct: 3835 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVK 3894

Query: 1947 QHESALEKIQYLEDDSRYK-------RAV---QDDSFVVEKPQF---GKPIKNAEVTEGH 1993
              E  ++  + ++   R K       +AV   +     +EK Q      P K  +  +  
Sbjct: 3895 SPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPIEKVQHLPVSAPPKITQFLKAE 3954

Query: 1994 PVHLEATLTPVNDPTM----RVEWYCNGRPVQQGHRFKTTYDF-GYVALDILYAYAEDTG 2048
                 A LT V + ++     V WY +G+ +++   F+  Y   G   L I      D G
Sbjct: 3955 ASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQG 4014

Query: 2049 TYMCKATNAVGEAVTTSSVKVDAKSGLY--LDTLDEQRL--KKIQELEKYERPKPIEEEQ 2104
             Y+C+ +   G + T       A   ++  +  + E +   +K  E     + +P   E 
Sbjct: 4015 EYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEP 4074

Query: 2105 PGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF 2164
               +PV +T L     +     A F   V+   +P  T  W  +G+ I  G +Y+ + D 
Sbjct: 4075 ISSKPVIVTGLQDT-TVSSDSVAKFA--VKATGEPRPTAIWTKDGKAITQGGKYKLSEDK 4131

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            G   L+I  T   DSG Y C   N  G   ++C L +
Sbjct: 4132 GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 4168



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 107/507 (21%), Positives = 192/507 (37%), Gaps = 29/507 (5%)

Query: 4309 VTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQT 4368
            VT        +QR ++ + ++  V  +  + +    P     SE         V  Q   
Sbjct: 3690 VTGGDYTTYASQRRDEEVPRS--VFPELTRTEAYAVPSFKKTSEMEASSSVREVKSQMTE 3747

Query: 4369 QKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQA 4428
             +E +   E +      ++  +E K+  +E+     +K +       K +   V+E E A
Sbjct: 3748 TRESLSSYEHSAS-AEMKSAALEEKS-LEEKSTTRKIKTTLAARILTKPRSMTVYEGESA 3805

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
            RF  + DGEP+P + W R+   +  S   Q+ T   KS   I  V   D   ++ V EN 
Sbjct: 3806 RFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 3865

Query: 4489 GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
             G  +    L +++ R   +    PP   + +    V S + V+   +V   +P     +
Sbjct: 3866 EGKQEAEFTLTIQKARVTEKAVTSPP--RVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAV 3923

Query: 4549 K-NGKKVQP--DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
                 K  P   +++  +      T  +     ++  K  CV  +S   A+   E     
Sbjct: 3924 SPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK---EVTWYK 3980

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
               K K     +   +     E LK   + E    E+ C+I G+         G      
Sbjct: 3981 DGKKLKENGHFQFHYSADGTYE-LKINNLTESDQGEYVCEISGE--------GGTSKTNL 4031

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
                Q  ++  E   +ISE    D+         +   VT   + K  +P  +  +  +T
Sbjct: 4032 QFMGQAFKSIHEKVSKISETKKSDQ-------KTTESTVTRKTEPKAPEPISSKPV-IVT 4083

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             L+D  V     A+F  + T + +PT  W ++G  I +   +++  +     L I  T  
Sbjct: 4084 GLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDT 4143

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
             D+G +TC    +AG V +S KL +K+
Sbjct: 4144 SDSGLYTCTVKNSAGSVSSSCKLTIKA 4170



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 63/267 (23%), Positives = 106/267 (39%), Gaps = 7/267 (2%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            ++ R   G N +F   ++  PT  V W      L E +K  + Y   +G ++L I     
Sbjct: 3608 RSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSK--IHYTNTSGVLTLEILDCHT 3665

Query: 139  GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
             D G Y     N  GE   S Y   +                 V  +V  +   T+ Y  
Sbjct: 3666 DDSGTYRAVCTNYKGER--SDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAV 3723

Query: 199  EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDR 258
               ++T ++  ++      +     +T E     E S    +    + E  ++      R
Sbjct: 3724 PSFKKTSEMEASSSVREVKSQ--MTETRESLSSYEHSASAEMKSAALEEKSLE-EKSTTR 3780

Query: 259  SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
             +      +I  KPR+  + EG  A+F     G P P VTW + G+ L  S +H++ TT 
Sbjct: 3781 KIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTK 3840

Query: 319  NHTTLRVRNTQKSDSGHYTLLAENPNG 345
              +T  + + Q SD G+Y+++ EN  G
Sbjct: 3841 YKSTFEISSVQASDEGNYSVVVENSEG 3867



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 111/485 (22%), Positives = 183/485 (37%), Gaps = 37/485 (7%)

Query: 3534 KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEW 3593
            K AALE  S    + T + ++       T P  + + E  SA F C      +    V W
Sbjct: 3764 KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTD--GEPVPTVTW 3821

Query: 3594 FHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHG-------------- 3639
               G+ L T +R +          EI  V   D G Y+    N  G              
Sbjct: 3822 LRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 3881

Query: 3640 --EATVSCKLQVKGRQGIILEPQL---PSHFKSGTESIQK-LEETLHKREEITIEDEKP- 3692
              E  V+   +VK  +  +  P+    P   KS   S  K +  T  K   I      P 
Sbjct: 3882 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPIEKVQHLPV 3941

Query: 3693 -NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLND 3749
              PP+ T  +K              C VE        + W+ +G+        + H   D
Sbjct: 3942 SAPPKITQFLKAEASKEIA---KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 3998

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE-SQLPQGM-SGEK 3807
             G   L I+ +   D GEY C  + + G++ T  +    A + I  + S++ +   S +K
Sbjct: 3999 -GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQK 4057

Query: 3808 IKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR 3867
              E    R ++    EPI S+ P  +T ++  TV      +F   V+   +P+    W +
Sbjct: 4058 TTESTVTRKTEPKAPEPI-SSKPVIVTGLQDTTVSSDSVAKFA--VKATGEPRPTAIWTK 4114

Query: 3868 NGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            +GK +  G +Y+   D G   L+I      DSG Y C   N  G   +   ++ K + D 
Sbjct: 4115 DGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD- 4173

Query: 3928 ILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVE 3987
              + Q     K SE   Q +A +++  S+  L  +++   + K   +   + ++   L+ 
Sbjct: 4174 -TEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLIS 4232

Query: 3988 METTK 3992
             E  K
Sbjct: 4233 EEVKK 4237



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 59/199 (29%), Positives = 85/199 (42%), Gaps = 5/199 (2%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSI 4467
            +PP FT  +     +  E  RF V     P P + WY+    IK   + + +TF S K +
Sbjct: 2915 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGL 2974

Query: 4468 --LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
              L I  V  +D A +  VA N+ G   C A L V           + P F     N   
Sbjct: 2975 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-TLHPPPTDSTLRPMFKRLLANAEC 3033

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKY 4584
              GQ V  + +V+G  P  + W K+G+ +      +I+ E    Y L I +  P+D+G Y
Sbjct: 3034 QEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 3093

Query: 4585 ECVAINSAGEARCDAECVV 4603
               A N+AG   C A   V
Sbjct: 3094 RVTATNTAGSTSCQAHLQV 3112



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 56/208 (26%), Positives = 92/208 (44%), Gaps = 11/208 (5%)

Query: 371  ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430
            IT T Q   E R     KA + Q         + EG+       + G    +V W +N  
Sbjct: 4252 ITKTSQASEEVRTHAEIKAFSTQM-------SINEGQRLVLKANIAGAT--DVKWVLNGV 4302

Query: 431  QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490
            ++ +   ++  V+ S +  L I   +  D G++TC+++ K G    Q  L  + KE   A
Sbjct: 4303 ELTNSEEYRYGVSGS-DQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDA 4360

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P F+ +  + N+ EG+ V+      G P+P I W K+ +PI  +  + I       +L+I
Sbjct: 4361 PAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 4420

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A  SD+  Y   A+N  G  +  A L
Sbjct: 4421 RNASVSDSGKYTIKAKNFRGQCSATASL 4448



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 150/731 (20%), Positives = 277/731 (37%), Gaps = 78/731 (10%)

Query: 1529 EVSCRLTCRSTTDIVRSTQNEAGLE-QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNV 1587
            EV  ++T   T + + S ++ A  E +   LE++S   ++      TT A    T  +++
Sbjct: 3740 EVKSQMT--ETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSM 3797

Query: 1588 EIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDS 1647
             + EG+ A F        +    V W    + L + +R   T        +I S    D 
Sbjct: 3798 TVYEGESARFS--CDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDE 3855

Query: 1648 GTYTCRAINALGEAVTSGIAIVH----SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQ 1703
            G Y+    N+ G+        +     ++K++    + +   PR+   E     +R  + 
Sbjct: 3856 GNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSP 3915

Query: 1704 D-----------------EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL---- 1742
            +                 E +   PV + P K  +  + +A+   A+L  V +  +    
Sbjct: 3916 EPSHPKAVSPTETKPTPIEKVQHLPV-SAPPKITQFLKAEASKEIAKLTCVVESSVLRAK 3974

Query: 1743 RVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
             V W ++G  ++ +      +   G   L +  +   D G Y C    E G + T+    
Sbjct: 3975 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 4034

Query: 1802 VQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVA--VNQAPRFITQLNGPTKLSEG 1859
             Q+  S+  +    S  +K  Q    S   R+ + +    ++  P  +T L   T +S  
Sbjct: 4035 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSSD 4093

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
              A +  +    P P     W  +GK +  G +Y+ S D G   L+I      DSG YTC
Sbjct: 4094 SVAKFAVKATGEPRPT--AIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 4151

Query: 1920 KAINNLGQAVSSIRLNVQS--------------------KESIIRDSQHESAL--EKIQY 1957
               N+ G   SS +L +++                    K++++++   + AL  E+I+ 
Sbjct: 4152 TVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKM 4211

Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVT--EGHPVHLEATLTPVNDPTMR----V 2011
             E  S+ K A+++++    K    + +K +  T  E   VH E T T      +R    +
Sbjct: 4212 SEAKSQEKLALKEEA---SKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEI 4268

Query: 2012 EWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
            + +     + +G R     +    A D+ +      G  +   +      V+ S   +  
Sbjct: 4269 KAFSTQMSINEGQRLVLKANIA-GATDVKWVL---NGVELTN-SEEYRYGVSGSDQTLTI 4323

Query: 2072 KSGLYLDTLDEQRLKKIQE-LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFE 2130
            K   + D      + K +E + K +    + +E     P F++   S +N+ EG    F 
Sbjct: 4324 KQASHRDEGILTCISKTKEGIVKCQYDLTLSKEL-SDAPAFISQPRS-QNINEGQNVLFT 4381

Query: 2131 CRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKL 2190
              +    +P   I+WF N   I        +      +L+I      DSG Y  KA N  
Sbjct: 4382 REIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFR 4439

Query: 2191 GEAVNTCTLKV 2201
            G+   T +L V
Sbjct: 4440 GQCSATASLMV 4450



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 140/668 (20%), Positives = 250/668 (37%), Gaps = 65/668 (9%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
            EG +A F        +P   V W + GR ++ S+R          +  I  ++A D G+Y
Sbjct: 3801 EGESARFSCDTD--GEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 3858

Query: 844  TVRAVNKLG--EAISTASIRVA--ARSTVTADLGI--PEQRRYIEKTXXXXXXXXXXXXX 897
            +V   N  G  EA  T +I+ A      VT+   +  PE R    +              
Sbjct: 3859 SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPS 3918

Query: 898  XXXXVPESTQKPEFKTPIKDQISI------KEGGFAHFEARLE------PIGDSTLR--- 942
                V  +  KP   TPI+    +      K   F   EA  E       +  S LR   
Sbjct: 3919 HPKAVSPTETKP---TPIEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKE 3975

Query: 943  VEWLKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            V W KDG+ ++ +      ++  G   L I ++T  D G Y C      G + T+     
Sbjct: 3976 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 4035

Query: 1002 VTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK--ITQKPRFLGPLKGTNKIVEGQ 1059
               K I  +       +K       S  +++TE +    I+ KP  +  L+ T  +    
Sbjct: 4036 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSSDS 4094

Query: 1060 SAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVV 1119
             A F   V+   +   T  W  +GK IT   + +   D G   L+I      DSG+YT  
Sbjct: 4095 VAKFA--VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCT 4152

Query: 1120 ARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQI-EEISKSKPV 1178
             +N+AG    S  +T++     +   +     +KT  I   K      +I ++  +S+ +
Sbjct: 4153 VKNSAGSVSSSCKLTIKAIKDTEAQKVST---QKTSEITPQKKAVVQEEISQKALRSEEI 4209

Query: 1179 FVQPLSNPPPVS---EGKNIHLECRLEPMGDPTMRVEWFHNGRSVT--VGSRFKTYYDFG 1233
             +    +   ++   E   + +   ++     ++     H   + T       +T+ +  
Sbjct: 4210 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 4269

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLED 1293
              +  +    S + G+  V   N  G+     ++  +E ++           +Q   ++ 
Sbjct: 4270 AFSTQM----SINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQ 4325

Query: 1294 AARR----------TKQ----VREDITVMQ----APQFSRALHNIETVEGTNVHLECRLQ 1335
            A+ R          TK+     + D+T+ +    AP F     +    EG NV     + 
Sbjct: 4326 ASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTREIS 4385

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G+ +  +EWF N  PI        +   +  +L++ +    DSG YT +A N  G+  
Sbjct: 4386 --GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 4443

Query: 1396 TSCALRVI 1403
             + +L V+
Sbjct: 4444 ATASLMVL 4451



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 97/477 (20%), Positives = 190/477 (39%), Gaps = 37/477 (7%)

Query: 2243 RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
            R +T+ R  T V+EG++A F C  +   +P   + +   G+ L ++AR  +T      + 
Sbjct: 3789 RILTKPRSMT-VYEGESARFSCDTDG--EPVPTVTWLRKGRVLSTSARHQVTTTKYKSTF 3845

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMT----------VTAKGSIISESQR---PEG 2349
            +I      D G YSV   N+ G   +  ++T          VT+   + S   R   PE 
Sbjct: 3846 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 3905

Query: 2350 LEKIRELESAEPFKRPEI------PEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPV 2403
            ++  + ++S EP     +      P P+ + + +       I    + + +    +L  V
Sbjct: 3906 VKSPKRVKSPEPSHPKAVSPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAKLTCV 3965

Query: 2404 GDPTL----KVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLG 2458
             + ++    +V W+++ K ++++      +   G   + I+++ + D+G Y+C  S   G
Sbjct: 3966 VESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGG 4025

Query: 2459 EXXXXXXXXXXXXXXIQLETQH-PEGMKKIQKLEQPHERRSEEPDREFEKPIFTQ--VLT 2515
                           I  +     E  K  QK  +    R  EP  +  +PI ++  ++T
Sbjct: 4026 TSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP--KAPEPISSKPVIVT 4083

Query: 2516 GPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVA 2575
            G  +      +  +  V   G+P     W  +G  +  G +++ + D G   L+I+    
Sbjct: 4084 GLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDT 4143

Query: 2576 NDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVD 2635
            +D+GLY C   N AG                  Q +  +   +I  ++ A+  V E    
Sbjct: 4144 SDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAV--VQEEISQ 4201

Query: 2636 TGVQQAPIFTTHLKSYDKLV---EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA 2689
              ++   I  +  KS +KL    E   V +  +V+     +L+       +T T+ A
Sbjct: 4202 KALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQA 4258



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 82/333 (24%), Positives = 143/333 (42%), Gaps = 40/333 (12%)

Query: 2924 VEGQVLHLEGQ--------VEPKN-DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLV 2974
            V GQ++H  G+         + +N D   ++ WYF  + LE   ++++T + G   L + 
Sbjct: 2797 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVK 2856

Query: 2975 DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRK 3034
            D+ + D G Y CK  N  GE  + + ++      + +   + + T  ++KI+   D++R 
Sbjct: 2857 DITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYD--YYCRRT--MKKIKRRTDTMRL 2912

Query: 3035 EPGQQPDDDTGRPPEFT-TVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA 3093
                       RPPEFT  ++     + E    +    +  T      + W+ +G+ I+ 
Sbjct: 2913 ---------LERPPEFTLPLYNKTAYVGE----NVRFGVTITVHPEPHVTWYKSGQKIKP 2959

Query: 3094 SHRIRTVYAF----GMVVLEILGTKTTDSGTYSCRATNKWGQ----AEISVKLECVDKSK 3145
                +  Y F    G+  L I    T D   Y+  A NK+G+    A+++V L       
Sbjct: 2960 GDNDKK-YTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDS 3018

Query: 3146 GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD-F 3204
              +P F   + N E  ++GQS  FE  V  +  P +K  W  +GQP+     I+ + +  
Sbjct: 3019 TLRPMFKRLLANAE-CQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGL 3075

Query: 3205 GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
             +  L I  T   D+G Y   A N  G    +A
Sbjct: 3076 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQA 3108



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 65/233 (27%), Positives = 101/233 (43%), Gaps = 16/233 (6%)

Query: 262  PVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
            PVS PPKI Q  +    +E A     V+ S      VTW+K+G++L  +   +   + + 
Sbjct: 3940 PVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 3999

Query: 321  T-TLRVRNTQKSDSGHYTLLAENPNGCIVT----------SGYLAVESPTESYVQDQRSQ 369
            T  L++ N  +SD G Y        G   T          S +  V   +E+   DQ++ 
Sbjct: 4000 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 4059

Query: 370  YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIND 429
              T T++ E +    IS K   P  V   QD  V+   + +F  + TG P P   W  + 
Sbjct: 4060 ESTVTRKTEPKAPEPISSK---PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDG 4116

Query: 430  RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            + I     +K L  + G   L I     SDSG+ TC  +N +G  +  C+L +
Sbjct: 4117 KAITQGGKYK-LSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 4168



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 94/350 (26%), Positives = 148/350 (42%), Gaps = 53/350 (15%)

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
            EG ++   C++E   D + +V W+   R +    +++  Y+ G   L +   T  D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 1251 TVRAVNHLG--SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVM 1308
              + VN  G  S++    V+ +     V D    + +++I+      RRT  +R    + 
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVRE---VYDYYCRRTMKKIK------RRTDTMR---LLE 2914

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP-AYEFD- 1366
            + P+F+  L+N     G NV     +    +    V W+ +G+ IK G   +   +E D 
Sbjct: 2915 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDK 2972

Query: 1367 -YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
                L + SV  +D   YT  A N+ GE   SC     AK  + L   HP          
Sbjct: 2973 GLYQLTINSVTTDDDAEYTVVARNKYGE--DSCK----AKLTVTL---HP---------- 3013

Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485
                   TD      T++P F  R  +     EGQ V FE ++  +    LK  W K+GQ
Sbjct: 3014 -----PPTD-----STLRPMF-KRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQ 3060

Query: 1486 PVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            P+++G     IH+   Y AL I D + ED+G Y   A N  G+      L
Sbjct: 3061 PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHL 3110



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 113/510 (22%), Positives = 191/510 (37%), Gaps = 51/510 (10%)

Query: 1374 SVYPE--DSGVYTCQATNQLGEAVTSCALRVIAK-----KDLILESQHPSGLE-KIQYLE 1425
            SV+PE   +  Y   +  +  E   S ++R +       ++ +   +H +  E K   LE
Sbjct: 3710 SVFPELTRTEAYAVPSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALE 3769

Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKN 1483
            + S  +K+       T+  R +T+P+S+  V EG+   F C    EPV      V W + 
Sbjct: 3770 EKSLEEKSTTRKIKTTLAARILTKPRSM-TVYEGESARFSCDTDGEPVPT----VTWLRK 3824

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT---CRSTT 1540
            G+ ++   R +          +I  + A D G Y+    N  G  E    LT    R T 
Sbjct: 3825 GRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTE 3884

Query: 1541 DIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQ------- 1593
              V S       E      +  K  +     E +    +  T  K   I++ Q       
Sbjct: 3885 KAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPIEKVQHLPVSAP 3944

Query: 1594 -------RAHFERRLIP----VSDATLK---VEWYHNNKPLKSGSRFT-ETNNFGFVALD 1638
                   +A   + +      V  + L+   V WY + K LK    F    +  G   L 
Sbjct: 3945 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 4004

Query: 1639 IMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQ--LEDTSK 1696
            I +    D G Y C      G + T+   +  + KSI+ +        + +Q   E T  
Sbjct: 4005 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 4064

Query: 1697 YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
             +      E I+  PV    ++D  V+ +  A F  +    G+P+    W ++G  I   
Sbjct: 4065 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKA--TGEPRPTAIWTKDGKAITQG 4122

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-------KASLQ 1809
             +     D G   L +   +  DSG YTC   N  G   +S  L +++       K S Q
Sbjct: 4123 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 4182

Query: 1810 LESQHESALQKIQQLEDSSRYQRREDVEVA 1839
              S+     + + Q E S +  R E+++++
Sbjct: 4183 KTSEITPQKKAVVQEEISQKALRSEEIKMS 4212



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 94/417 (22%), Positives = 163/417 (39%), Gaps = 45/417 (10%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            S P+     ++   +    AKF  K  G P P   WT+    + +  KY +  +E  G  
Sbjct: 4077 SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL--SEDKGGF 4134

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
             L I +    D G YTCT +N  G    S  +  +               +  SE    K
Sbjct: 4135 FLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVST---QKTSEITPQK 4191

Query: 190  AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREV--SFRESITKRYVGE 247
                Q   ++++ +++++  +           K +  +  +  EV  S   S+ K  V E
Sbjct: 4192 KAVVQEEISQKALRSEEIKMSEAKSQEKLA-LKEEASKVLISEEVKKSAATSLEKSIVHE 4250

Query: 248  SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307
               +I+     S    +  +I        + EG     +  ++G     V W  NG  L 
Sbjct: 4251 ---EITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVELT 4305

Query: 308  NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
            NS ++    + +  TL ++     D G  T        CI         S T+  +   +
Sbjct: 4306 NSEEYRYGVSGSDQTLTIKQASHRDEGILT--------CI---------SKTKEGIV--K 4346

Query: 368  SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
             QY     +       E+S+   AP F+   + +++ EG+   F   ++G P PE+ WF 
Sbjct: 4347 CQYDLTLSK-------ELSD---APAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFK 4396

Query: 428  NDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            N+  I    N  + ++ S N ++L I N ++SDSG  T  A+N  G+ +    L V+
Sbjct: 4397 NNLPISISSN--VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 4451



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 67/284 (23%), Positives = 117/284 (41%), Gaps = 17/284 (5%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F    ++    +G N  F  ++ G P+P + W +   P+   +  S+  +      SL
Sbjct: 4361 PAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISRSRNV--YSL 4418

Query: 132  LIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
             I+     D G+YT  A+N  G+  A  S+ + P                R   +T    
Sbjct: 4419 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLP-----LVEEPSREVVLRTSGDTSLQG 4473

Query: 190  AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREV--SFRESITKRYVGE 247
            ++ +Q      S+Q    +  + +  SS  + K  +   + +  +  SF E  +  ++G 
Sbjct: 4474 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 4533

Query: 248  SDV-QISTEIDRSLGPVS---PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
            S++ Q+ +   + L       PPKI   P +  + EG         +G P P VTW   G
Sbjct: 4534 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 4593

Query: 304  QRLIN--SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            +++ +    +  I  T + TTL + + QK D G YTL   N  G
Sbjct: 4594 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 4637



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 85/361 (23%), Positives = 147/361 (40%), Gaps = 22/361 (6%)

Query: 513  RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN----V 568
            +A G P P   W KDG  I    + ++  D G   L+I +   SD+  Y CT +N    V
Sbjct: 4101 KATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSV 4160

Query: 569  AGSTATRARLYXXXXXXXXXXQKRLHLPRPTK--VXXXXXXXXXXXXYLRHVE-RARPYI 625
            + S     +            QK   +    K  V             ++  E +++  +
Sbjct: 4161 SSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKL 4220

Query: 626  PPGEE-DRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
               EE  +V    +  V   + T++E   +H     E +   +   E ++    I+A S 
Sbjct: 4221 ALKEEASKVLISEE--VKKSAATSLEKSIVH-----EEITKTSQASEEVRTHAEIKAFST 4273

Query: 685  FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK-AVLHVTPRATIERTSQHPE- 742
              SI     + L        D  ++    V  T   E +  V       TI++ S   E 
Sbjct: 4274 QMSINEGQRLVLKANIAGATDV-KWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 4332

Query: 743  TLQYIQQL-EDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPT 801
             L  I +  E   K Q+  ++ ++ S  P FI   +    + EG+N  F  +++   +P+
Sbjct: 4333 ILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQN-INEGQNVLFTREIS--GEPS 4389

Query: 802  MRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIR 861
              +EW+K+  PI+ SS ++   +    SL I +    D+G YT++A N  G+  +TAS+ 
Sbjct: 4390 PEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLM 4449

Query: 862  V 862
            V
Sbjct: 4450 V 4450



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 52/182 (28%), Positives = 81/182 (44%), Gaps = 2/182 (1%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHA 449
            AP F +  ++ +V         C+VTG P P V W+   ++I  D   ++I   + G H 
Sbjct: 2154 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 2213

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L+I +VT  D+ V    A N+ G  +    L V    ++  PK +E    ++   GE V 
Sbjct: 2214 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVS 2273

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR-AKASDAAWYQCTAQNV 568
            +     G P P ITWQK    I  N   ++      ++L  P   +  DA +Y   A+N 
Sbjct: 2274 IKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNR 2333

Query: 569  AG 570
             G
Sbjct: 2334 FG 2335



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 83/384 (21%), Positives = 153/384 (39%), Gaps = 28/384 (7%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG++  F C+ +    PT  + W    + L +  R++ T      + +I+     D G Y
Sbjct: 3801 EGESARFSCDTDGEPVPT--VTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 3858

Query: 2847 TCKATNSKGSATTSGSLRC----TGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPS 2902
            +    NS+G      +L        +K +    +    +  +++ E  +  +  K   PS
Sbjct: 3859 SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPS 3918

Query: 2903 VPDTEYP---KPEWI-----IPIAAEHQLVE-------GQVLHLEGQVEPKNDPDLKIEW 2947
             P    P   KP  I     +P++A  ++ +        ++  L   VE       ++ W
Sbjct: 3919 HPKAVSPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTW 3978

Query: 2948 YFNGKVLEQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            Y +GK L++   F+   S  G   L + ++ E D G Y C+   + G + T+      + 
Sbjct: 3979 YKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAF 4038

Query: 3007 DNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIA 3066
             ++ E+      T+  ++        RK   + P+  + +P    T  +D   +S   +A
Sbjct: 4039 KSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV-IVTGLQDTT-VSSDSVA 4096

Query: 3067 HYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRAT 3126
             +      TG+      W  +GK I    + +     G   LEI  T T+DSG Y+C   
Sbjct: 4097 KFAVKA--TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK 4154

Query: 3127 NKWGQAEISVKL--ECVDKSKGQK 3148
            N  G    S KL  + +  ++ QK
Sbjct: 4155 NSAGSVSSSCKLTIKAIKDTEAQK 4178



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 70/280 (25%), Positives = 120/280 (42%), Gaps = 20/280 (7%)

Query: 922  KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
            +EGG   +  ++E    ST +V W    R +E S +    +  G   L +K +T  D G 
Sbjct: 2807 EEGGHVKYVCKIENYDQST-QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 2865

Query: 982  YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            Y C+  N  G+ ++ A L +   +++              Y     +  KR  + +++ +
Sbjct: 2866 YRCKVVNDYGEDSSYAELFVKGVREVYD-----------YYCRRTMKKIKRRTDTMRLLE 2914

Query: 1042 K-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY---HD 1097
            + P F  PL      V G++  F   +    +  +T  WY +G++I   +  + Y    D
Sbjct: 2915 RPPEFTLPLYNKTAYV-GENVRFGVTITVHPEPHVT--WYKSGQKIKPGDNDKKYTFESD 2971

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
             G   L I SV  +D   YTVVARN  GE    A +TV T     T S  R ++++    
Sbjct: 2972 KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-TLHPPPTDSTLRPMFKRLLAN 3030

Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHL 1197
             E +  + +     +S   P  ++   +  P+S G NI +
Sbjct: 3031 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEI 3070



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 46/192 (23%), Positives = 84/192 (43%), Gaps = 3/192 (1%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I + +KD     G+A + SC+IVG+PLP ++WY+  K +  S+ ++MS     +TL +
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                 EDEG Y C+A N  G V  ++KL +    Q    P            G   +   
Sbjct: 1820 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFH--PGYPLKEKYYGAVGSTLRLHV 1877

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE-DTGTFTCRATTAAGQ 4801
                +  P + W     L+  + +  + +  +   L++ N   +   G +  + +   G 
Sbjct: 1878 MYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 1937

Query: 4802 VETSAKLVVKSK 4813
            V+    + ++ K
Sbjct: 1938 VDAILDVEIQDK 1949



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 64/235 (27%), Positives = 103/235 (43%), Gaps = 28/235 (11%)

Query: 3839 HTVEESEG-VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            H V E  G V++ C++E   D   ++ WY   + L +  +Y   Y+ G   L +  +   
Sbjct: 2803 HAVGEEGGHVKYVCKIE-NYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 2861

Query: 3898 DSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEV 3957
            D G Y C+ VND+GED + A +  K + + +      R MK+          IK+ T  +
Sbjct: 2862 DDGTYRCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKK----------IKRRTDTM 2910

Query: 3958 YLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG---K 4014
             L E         +PP F   + ++T+ V  E  +F   +    +P+  V W+ +G   K
Sbjct: 2911 RLLE---------RPPEFTLPLYNKTAYVG-ENVRFGVTITVHPEPH--VTWYKSGQKIK 2958

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            P  +  ++T   D G   +    V  +D  EY   A N YG D  KA +  T  P
Sbjct: 2959 PGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP 3013



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 85/377 (22%), Positives = 145/377 (38%), Gaps = 35/377 (9%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + EG++A F C     G+P   V W R  +++  S+R   T      +  IS V+  DEG
Sbjct: 3799 VYEGESARFSCDTD--GEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEG 3856

Query: 2448 VYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ-KLEQPHE----RRSEEPD 2502
             Y     N  G+               +     P  +K  + +++ P      +R + P+
Sbjct: 3857 NYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPE 3916

Query: 2503 REFEKPIFTQVLTGPSELWEGQH----------------AHYE-ARVVPVGDPSL----R 2541
                K + +   T P+ + + QH                A  E A++  V + S+     
Sbjct: 3917 PSHPKAV-SPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKE 3975

Query: 2542 FEWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXX 2600
              WY +G +LK    F+  +   G   L IN++  +D G Y+C+     G          
Sbjct: 3976 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 4035

Query: 2601 XXXXXIIDQAMRPESWEQIQLK--EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQ 2658
                 I ++  +    ++   K  E+ + +  E      +   P+  T L+  D  V   
Sbjct: 4036 QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQ--DTTVSSD 4093

Query: 2659 HVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCK 2718
             V   A V+   +P     W K+G  +T G + K + D G   L I+     DSG+YTC 
Sbjct: 4094 SVAKFA-VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCT 4152

Query: 2719 ATNLLGEAVSTASIKIE 2735
              N  G   S+  + I+
Sbjct: 4153 VKNSAGSVSSSCKLTIK 4169



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 87/390 (22%), Positives = 146/390 (37%), Gaps = 19/390 (4%)

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            +A + + +  ++ V EGE    +    G P P +TW + G  +  +   ++ T    ST 
Sbjct: 3786 LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTF 3845

Query: 549  DIPRAKASDAAWYQCTAQNVAGS-----TATRARLYXXXXXXXXXXQKRLHLPR---PTK 600
            +I   +ASD   Y    +N  G      T T  +            + +   PR   P  
Sbjct: 3846 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 3905

Query: 601  VXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYP---PPQFIVPLKSVTAMEGGKIHFE 657
            V            + + V        P E+ +  P   PP+    LK+  + E  K+   
Sbjct: 3906 VKSPKRVKSPEPSHPKAVSPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAKL--T 3963

Query: 658  TRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSA 716
              +E       ++ W K+G+ ++ +  F   +   G   L + +L   D GEY C     
Sbjct: 3964 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGE 4023

Query: 717  TGVAETKAVLHVTPRATI-ERTSQHPETLQYIQQLEDYSKYQHQE-SIEEQTSQRPQFIR 774
             G ++T          +I E+ S+  ET +  Q+  + +  +  E    E  S +P  + 
Sbjct: 4024 GGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVT 4083

Query: 775  PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMH 834
             LQD   +     A F  + T    PT    W KDG+ IT   +     + G   L I  
Sbjct: 4084 GLQDT-TVSSDSVAKFAVKATGEPRPT--AIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 4140

Query: 835  LRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
                D+G YT    N  G   S+  + + A
Sbjct: 4141 TDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 4170



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 91/390 (23%), Positives = 149/390 (38%), Gaps = 31/390 (7%)

Query: 3283 KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
            + +T+ + +T + EG+SA F        +P   V W   G+ L    R++          
Sbjct: 3789 RILTKPRSMT-VYEGESARFSCDTD--GEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTF 3845

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANL---KCTSKENLILDSQLPRGMEGGLEKLQT 3399
            +I      + G Y  V  N  G+   +  L   K    E  +      +  E  ++  + 
Sbjct: 3846 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 3905

Query: 3400 LEDSMVRRKDTSVEEEKGKAPVFT--VPLSNIENLR-----------EGENAHFEARLTP 3446
            ++ S  R K       K  +P  T   P+  +++L            + E +   A+LT 
Sbjct: 3906 VK-SPKRVKSPEPSHPKAVSPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAKLTC 3964

Query: 3447 TDDPNL----KVEWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNY 3501
              + ++    +V WY +GK LK    F+  +   G   L+I+     D GEY+C      
Sbjct: 3965 VVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEG 4024

Query: 3502 GEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIAALEGYSGTVDTLTPEAESGNPPEF 3560
            G + T      Q  ++I    ++ K  E    D+       +   +   PE  S  P   
Sbjct: 4025 GTSKTNLQFMGQAFKSI--HEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV-I 4081

Query: 3561 TTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIG 3620
             T   D  +S +S A F  +     +      W  +GK +  G + K   D G   LEI 
Sbjct: 4082 VTGLQDTTVSSDSVAKFAVKA--TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIH 4139

Query: 3621 GVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
                 D+GLYTC   N  G  + SCKL +K
Sbjct: 4140 KTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 4169



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 61/306 (19%), Positives = 128/306 (41%), Gaps = 17/306 (5%)

Query: 4308 KVTSNTVAKSMAQRYEDNLDQTEEVTEQR---VQKKVTQKPRIPDPSESTVHGKEVHVAK 4364
            K+T   +  + AQ+   +  +T E+T Q+   VQ++++QK    +  + +    +  +A 
Sbjct: 4165 KLTIKAIKDTEAQKV--STQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLAL 4222

Query: 4365 QKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFE 4424
            +++  K ++ ++      TS E + +  +     +  E     ++   F+ +M    + E
Sbjct: 4223 KEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMS---INE 4279

Query: 4425 HEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484
             ++   +    G     +KW      + NS +++     +   L I+Q    D  +   +
Sbjct: 4280 GQRLVLKANIAGATD--VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCI 4337

Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
            ++ + G  KC  +L + ++          P+F    ++ N+  GQ V    +++G    +
Sbjct: 4338 SKTKEGIVKCQYDLTLSKELSDA------PAFISQPRSQNINEGQNVLFTREISGEPSPE 4391

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            + W KN   +       I      Y+L I  A   DSGKY   A N  G+    A  +V 
Sbjct: 4392 IEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV- 4450

Query: 4605 LPATKD 4610
            LP  ++
Sbjct: 4451 LPLVEE 4456



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 56/215 (26%), Positives = 95/215 (44%), Gaps = 17/215 (7%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EGG V + C++E   D + ++ W+   R      +     + G   L +  I   D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C+  N +G  ++ A++     R+ V +    + M  +KIK     R +D  +   ++  
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTM--KKIK-----RRTDTMR---LLER 2915

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG---HRYRTVYDMG 3885
            PP+F   + + T    E VRF   +    +P   + WY++G+ +  G    +Y    D G
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 2973

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
               L I  V  +D  EY   A N +GED  KA ++
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLT 3008



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 80/338 (23%), Positives = 140/338 (41%), Gaps = 52/338 (15%)

Query: 1739 DPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
            D   +V W      +E S +    ++ G   L +K +   D GTY C+ +N+ GE  + +
Sbjct: 2822 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 2881

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE 1858
             LFV+    +  +      ++KI++  D+ R   R          P F   L   T    
Sbjct: 2882 ELFVKGVREVY-DYYCRRTMKKIKRRTDTMRLLERP---------PEFTLPLYNKTAYV- 2930

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G++  +   I  +P+P+  V WY +G+ ++ G      ND  +        +  D G Y 
Sbjct: 2931 GENVRFGVTITVHPEPH--VTWYKSGQKIKPG-----DNDKKYT-------FESDKGLYQ 2976

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQ-----DDSF 1973
                      ++S+  +         D    + + + +Y ED  + K  V       DS 
Sbjct: 2977 L--------TINSVTTD---------DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDST 3019

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD-F 2032
            +  +P F + + NAE  EG  V  E  ++ +  PT++  W  +G+P+  G   +  ++  
Sbjct: 3020 L--RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGL 3075

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             Y AL I     EDTG Y   ATN  G     + ++V+
Sbjct: 3076 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 3113



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 88/324 (27%), Positives = 125/324 (38%), Gaps = 61/324 (18%)

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ----A 3132
            DQS  + W++  + +E S +    Y  G+ +L +      D GTY C+  N +G+    A
Sbjct: 2822 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 2881

Query: 3133 EISVK-------LECVDKSKGQK------------PRFTTHIQNIEGLKDGQSAHFECTV 3173
            E+ VK         C    K  K            P FT  + N      G++  F  T+
Sbjct: 2882 ELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYV-GENVRFGVTI 2940

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTV---SDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
                 P+  + WY +GQ ++     K     SD G   L I      D  EY   A NKY
Sbjct: 2941 TV--HPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKY 2998

Query: 3231 GEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQD 3290
            GED      +C  K  V   +L P                   P T S   P F   + +
Sbjct: 2999 GED------SCKAKLTV---TLHP-------------------PPTDSTLRPMFKRLLAN 3030

Query: 3291 VTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD-FGIVILDILYCYE 3349
              +  EGQS  FE R+  +  P LK  W  +G+ L  G      H+      L I     
Sbjct: 3031 A-ECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLP 3087

Query: 3350 ENSGEYECVATNKLGRDSTKANLK 3373
            E++G Y   ATN  G  S +A+L+
Sbjct: 3088 EDTGYYRVTATNTAGSTSCQAHLQ 3111



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 50/190 (26%), Positives = 87/190 (45%), Gaps = 14/190 (7%)

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            +++  GQ + L   + G    DV W+ NG ++      +        TL I +A  +D G
Sbjct: 4275 MSINEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 4332

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
               C++    G  +C  +  +S            + ++AP  I +P + + + EGQ + F
Sbjct: 4333 ILTCISKTKEGIVKCQYDLTLS-----------KELSDAPAFISQP-RSQNINEGQNVLF 4380

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
            + +I G+P P ++W+K +  I  S    +SR+ + Y+L I  A   D G Y   A N  G
Sbjct: 4381 TREISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRG 4440

Query: 4703 RVTVAAKLKV 4712
            + +  A L V
Sbjct: 4441 QCSATASLMV 4450



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 46/174 (26%), Positives = 87/174 (50%), Gaps = 9/174 (5%)

Query: 235  SFRESITKRYVGESDVQISTE--IDRSLGPVSPPKIAQKP------RNSKLQEGADAQFQ 286
            S  E ++K    +   Q +TE  + R   P +P  I+ KP      +++ +   + A+F 
Sbjct: 4040 SIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFA 4099

Query: 287  VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC 346
            V+ +G PRP   W K+G+ +    K+++        L +  T  SDSG YT   +N  G 
Sbjct: 4100 VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGS 4159

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITD-TQQRETEERIEISEKALAPQFVKVCQ 399
            + +S  L +++  ++  Q   +Q  ++ T Q++   + EIS+KAL  + +K+ +
Sbjct: 4160 VSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSE 4213



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 57/205 (27%), Positives = 88/205 (42%), Gaps = 20/205 (9%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
            D   +V W++  ++L +  +Y   ++ G+ IL +    + + G Y C   N  G DS+ A
Sbjct: 2822 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 2881

Query: 3371 NLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIE 3430
             L        + D    R M+            + RR DT    E+   P FT+PL N +
Sbjct: 2882 ELFVKGVRE-VYDYYCRRTMK-----------KIKRRTDTMRLLER--PPEFTLPLYN-K 2926

Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC---DFGFVILEISPTYP 3487
                GEN  F   +T   +P+  V WY +G+ +K G   + +    D G   L I+    
Sbjct: 2927 TAYVGENVRFGVTITVHPEPH--VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTT 2984

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKV 3512
            +D  EY   A N YGE    A + V
Sbjct: 2985 DDDAEYTVVARNKYGEDSCKAKLTV 3009



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 62/243 (25%), Positives = 103/243 (42%), Gaps = 25/243 (10%)

Query: 4481 FAAVAENRGGTAKCSANLV-VEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG 4539
            F   AEN  G ++     + ++ K   G      P      ++V    G+  +L  ++ G
Sbjct: 1730 FRVFAENETGLSRPRRTAMSIKTKLTSGEA----PGIRKEMKDVTTKLGEAAQLSCQIVG 1785

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                D+ W + GK++    + K+  +  T+TL ++    +D G Y C+A N  GE    +
Sbjct: 1786 RPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSS 1845

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV-AEGQAIEFSCKIVGKPLPTVQWYK 4658
            + +  L AT     PQ            PLK+K   A G  +      +G+P+P + W+ 
Sbjct: 1846 KLL--LQAT-----PQFHPG-------YPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFH 1891

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPE--DEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            G KL++ S+   +  T + YT  + +        G YK    N  G  TV A L V   D
Sbjct: 1892 GQKLLQNSENITIENT-EHYTHLVMKNVQRKTHAGKYKVQLSNVFG--TVDAILDVEIQD 1948

Query: 4717 QAD 4719
            + D
Sbjct: 1949 KPD 1951



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 96/442 (21%), Positives = 164/442 (37%), Gaps = 42/442 (9%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVE--GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEF 4434
            E   KI+ T+ ++ +    T  R  E   P   S  P+    +Q   V     A+F V+ 
Sbjct: 4043 EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKA 4102

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
             GEP P   W ++   I     +++        L I +    DS ++    +N       
Sbjct: 4103 TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSA----- 4157

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
                           G V  S  LT + +  T  Q      KV+  K  ++   K    V
Sbjct: 4158 ---------------GSVSSSCKLTIKAIKDTEAQ------KVSTQKTSEITPQKKAV-V 4195

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQD--SGKYECVAINSAGEARCDAECVVSLPATKD-- 4610
            Q +I  K L  +    + + EA  Q+  + K E   +  + E +  A   +      +  
Sbjct: 4196 QEEISQKALRSE---EIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEI 4252

Query: 4611 -KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYF 4669
             K    ++      EI        + EGQ +     I G     V+W      +  S+ +
Sbjct: 4253 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEY 4310

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLR 4728
            +   +  + TL I +A   DEG   C++    G   V  +  +T   +  + PA ++  R
Sbjct: 4311 RYGVSGSDQTLTIKQASHRDEGILTCISKTKEG--IVKCQYDLTLSKELSDAPAFISQPR 4368

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
               + EGQ   F  +I+ +  P I+W +    I  + +  +    N   L I N    D+
Sbjct: 4369 SQNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 4428

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G +T +A    GQ   +A L+V
Sbjct: 4429 GKYTIKAKNFRGQCSATASLMV 4450



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 145/697 (20%), Positives = 268/697 (38%), Gaps = 67/697 (9%)

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            LE+ S  ++ + +    T A       + + V E ++A F       G+P   V WLR G
Sbjct: 3768 LEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTD--GEPVPTVTWLRKG 3825

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ----SKA 1806
              +  S R             +  V   D G Y+    N  G+     TL +Q    ++ 
Sbjct: 3826 RVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEK 3885

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQA-------PRFITQL-----NGPT 1854
            ++    + +S   +++  E     +R +  E +  +A       P  I ++     + P 
Sbjct: 3886 AVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPIEKVQHLPVSAPP 3945

Query: 1855 KLSE-------GQSAHYECRIEPYPDPNMRVEWYFNGKVL-QSGH-RYRTSNDFGFAALD 1905
            K+++        + A   C +E        V WY +GK L ++GH ++  S D G   L 
Sbjct: 3946 KITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD-GTYELK 4004

Query: 1906 ILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYK 1965
            I  +   D GEY C+     G + ++++   Q+ +SI       S  +K      +S   
Sbjct: 4005 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 4064

Query: 1966 RAVQDDSF--VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023
            R  +  +   +  KP     +++  V+           T   +P     W  +G+ + QG
Sbjct: 4065 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT--GEPRPTAIWTKDGKAITQG 4122

Query: 2024 HRFKTTYDFGYVALDILYAYAEDTGTYM-------------CKAT-NAVG--EAVTTSSV 2067
             ++K + D G   L+I      D+G Y              CK T  A+   EA   S+ 
Sbjct: 4123 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 4182

Query: 2068 KVDA----KSGLYLDTLDEQRLK----KIQELEKYERPKPIEEEQPG--QRPVFLTALTS 2117
            K       K  +  + + ++ L+    K+ E +  E+    EE         V  +A TS
Sbjct: 4183 KTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATS 4242

Query: 2118 LENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE 2177
            LE     +      +       H  I  F     I  G R     +    A D+ +    
Sbjct: 4243 LEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG-ATDVKWVLNG 4301

Query: 2178 DSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEP 2237
               T   +    +  +  T T+K A HR+  + T      E I + +       + + + 
Sbjct: 4302 VELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYD-----LTLSKE 4356

Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297
                P F+++ R + ++ EG+   F  ++    +P+  IE++ N   +  ++   I+   
Sbjct: 4357 LSDAPAFISQPR-SQNINEGQNVLFTREISG--EPSPEIEWFKNNLPISISSNVSISRSR 4413

Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
               SL+I++    D+G+Y++KA N  G C++  S+ V
Sbjct: 4414 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 4450



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 55/218 (25%), Positives = 95/218 (43%), Gaps = 18/218 (8%)

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            ++G    + C +   D    ++ WY   + + +S + +   + G  +L +      D G 
Sbjct: 2807 EEGGHVKYVCKIENYDQ-STQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 2865

Query: 3222 YVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE- 3280
            Y C+  N YGED + A +   G   VY      D   +     +++  +++T +    E 
Sbjct: 2866 YRCKVVNDYGEDSSYAELFVKGVREVY------DYYCR----RTMKKIKRRTDTMRLLER 2915

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG---HRYRTFHDF 3337
            PP+F   + + T  V G++  F   +     P+  V W+ +G+K+  G    +Y    D 
Sbjct: 2916 PPEFTLPLYNKTAYV-GENVRFGVTITV--HPEPHVTWYKSGQKIKPGDNDKKYTFESDK 2972

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
            G+  L I     ++  EY  VA NK G DS KA L  T
Sbjct: 2973 GLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 3010



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 6/136 (4%)

Query: 232  REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
            R+      I+K   G    Q    + + L     P    +PR+  + EG +  F  ++SG
Sbjct: 4329 RDEGILTCISKTKEGIVKCQYDLTLSKELSDA--PAFISQPRSQNINEGQNVLFTREISG 4386

Query: 292  NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG-CIVTS 350
             P P + WFKN   +  S+   I  + N  +L +RN   SDSG YT+ A+N  G C  T+
Sbjct: 4387 EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 4446

Query: 351  GYLA---VESPTESYV 363
              +    VE P+   V
Sbjct: 4447 SLMVLPLVEEPSREVV 4462



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 81/337 (24%), Positives = 134/337 (39%), Gaps = 43/337 (12%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
            EG +V   C+++   DQ+ +V W+   + ++   ++   YE     L +  +   D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 1384 TCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIK 1443
             C+  N  GE  +   L V   ++ + +      ++KI+   DT R  +          +
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKRRTDTMRLLE----------R 2915

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P   T P   +    G++V F   +    + +  V W+K+GQ +  G      +D  Y  
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPH--VTWYKSGQKIKPGD-----NDKKYT- 2967

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
                     D G+Y    +N V TD+ +        T + R+   E   +    +     
Sbjct: 2968 ------FESDKGLYQL-TINSVTTDDDA------EYTVVARNKYGEDSCKAKLTVTLHPP 3014

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
               TD     +T  P+    L N E +EGQ   FE R+  +   TLK  W  + +PL  G
Sbjct: 3015 --PTD-----STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLG 3065

Query: 1624 SRFTETN-NFGFVALDIMSCLPEDSGTYTCRAINALG 1659
                  +    + AL I   LPED+G Y   A N  G
Sbjct: 3066 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 3102



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 55/229 (24%), Positives = 92/229 (40%), Gaps = 16/229 (6%)

Query: 2122 KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
            +EG    + C++E   D    + W+   +++    +Y  T++ G   L +      D GT
Sbjct: 2807 EEGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 2865

Query: 2182 YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISP 2241
            Y CK  N  GE  +   L V G R  + D      ++KI++        R +       P
Sbjct: 2866 YRCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKR--------RTDTMRLLERP 2916

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ---SAARFHITFDFG 2298
            P F   L   T  + G+   F   +  VH P   + +Y +G+ ++   +  ++    D G
Sbjct: 2917 PEFTLPLYNKT-AYVGENVRFGVTI-TVH-PEPHVTWYKSGQKIKPGDNDKKYTFESDKG 2973

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
               L I     +D  EY+V A N  G  +    +TVT        + RP
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 3022



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 79/290 (27%), Positives = 112/290 (38%), Gaps = 26/290 (8%)

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG- 4539
            F    EN GG ++ S   + E    +    I  P F    +N+NV       L  KVTG 
Sbjct: 2124 FRVKCENLGGESEWSE--ISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGH 2181

Query: 4540 TKPIDVYWLKNGKKVQPD-IRNKILEEDGTYTLLILEAYPQDSGK-YECVAINSAGEARC 4597
             KPI V W + GK++  D ++ +I E  G Y  LI+ +   D    Y+  A N  G    
Sbjct: 2182 PKPI-VKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSG 2240

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             A   V +PA    PK            +E +       G+ +       GKP P + W 
Sbjct: 2241 TASLEVEVPAKIHLPK-----------TLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ 2289

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFP-EDEGDYKCVAYNSAGRVTVAAKLKVTQ-P 4715
            KG  LI  + ++Q+  T    +L        +D G Y   A N  G      +L V   P
Sbjct: 2290 KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVP 2349

Query: 4716 DQADNLPALTPLRDIV-VYEGQPA-----QFKTQITSKIKPTIQ-WLREG 4758
            D    +      RD V +   +PA     +    I  K   T + WLR G
Sbjct: 2350 DPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG 2399



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 81/358 (22%), Positives = 141/358 (39%), Gaps = 54/358 (15%)

Query: 3571 ENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLY 3630
            E     + C+ I   D S +V W+   + L    + +   + G  IL +  + + D G Y
Sbjct: 2808 EGGHVKYVCK-IENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 3631 TCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDE 3690
             CK  N +GE +   +L VKG + +        + +   + I++  +T+   E       
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREVY-----DYYCRRTMKKIKRRTDTMRLLER------ 2915

Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTL- 3747
               PP FT+ +  N     G  V F   +    +P   + W+ +G+    G   + +T  
Sbjct: 2916 ---PPEFTLPLY-NKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFE 2969

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEK 3807
            +D G   L I+ +   D  EYT  A NK+G  +      C AK  + L            
Sbjct: 2970 SDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS------CKAKLTVTLHPP--------- 3014

Query: 3808 IKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR 3867
                        P +  +    P F   + +   +E + V FE RV     P L+  W +
Sbjct: 3015 ------------PTDSTL---RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEK 3057

Query: 3868 NGKLLPSGHRYRTVYD-MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
            +G+ L  G     +++ + + +L I     ED+G Y   A N  G    +A +  ++L
Sbjct: 3058 DGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERL 3115



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 88/378 (23%), Positives = 137/378 (36%), Gaps = 41/378 (10%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            ++ V EG    F C  +  G+P   + W   GR  +T +R            +I  + A 
Sbjct: 3796 SMTVYEGESARFSCDTD--GEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQAS 3853

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIV--------LESQLPQGMSGEKIKELERGR 3815
            D G Y+    N  G       +T    R           ++S  P+  S E +K  +R +
Sbjct: 3854 DEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVK 3913

Query: 3816 ISD-------APKEE---PI-------VSTPPKFITQIKSHTVEESEGVRFECRVEPKED 3858
              +       +P E    PI       VS PPK    +K+   +E    +  C VE    
Sbjct: 3914 SPEPSHPKAVSPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEI--AKLTCVVESSVL 3971

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKA 3917
                + WY++GK L     ++  Y   G   L I  +   D GEY+C    + G   T  
Sbjct: 3972 RAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNL 4031

Query: 3918 TISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVT 3977
                +    I  +       K+S+  T  E+T+ + T E    E     +  K  P  VT
Sbjct: 4032 QFMGQAFKSIHEKVSKISETKKSDQKTT-ESTVTRKT-EPKAPEP----ISSK--PVIVT 4083

Query: 3978 QIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGW 4037
             +Q  T++      KF  +    G+P     W  +GK +    ++    D G   +    
Sbjct: 4084 GLQD-TTVSSDSVAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 4140

Query: 4038 VYPEDSGEYLCRATNLYG 4055
                DSG Y C   N  G
Sbjct: 4141 TDTSDSGLYTCTVKNSAG 4158



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 52/221 (23%), Positives = 90/221 (40%), Gaps = 27/221 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL---INSNKHEIITTHNHT 321
            PP+      N     G + +F V ++ +P P VTW+K+GQ++    N  K+   +     
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 2975

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
             L + +    D   YT++A N                   Y +D     +T T       
Sbjct: 2976 QLTINSVTTDDDAEYTVVARN------------------KYGEDSCKAKLTVTLHPPP-- 3015

Query: 382  RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
                ++  L P F ++  + +  EG+   F+ RV+G P P + W  + + +    N +I+
Sbjct: 3016 ----TDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII 3071

Query: 442  VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
                  +AL I +    D+G     A N +G T+ Q  L V
Sbjct: 3072 HEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 3112



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 52/229 (22%), Positives = 96/229 (41%), Gaps = 9/229 (3%)

Query: 2795 CNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVSLDITHTYEEDSGIYTCKATN 2852
            C VE S     ++ W+ + K L     ++  +  D +Y  L I +  E D G Y C+ + 
Sbjct: 3964 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTY-ELKINNLTESDQGEYVCEISG 4022

Query: 2853 SKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPE 2912
              G++ T+        K+I+            ++ ++  E+ + +   P  P+    KP 
Sbjct: 4023 EGGTSKTNLQFMGQAFKSIHEKVSKISETK--KSDQKTTESTVTRKTEPKAPEPISSKP- 4079

Query: 2913 WIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLD 2972
             +I    +   V    +  +  V+   +P     W  +GK + QG ++KL+ D G   L+
Sbjct: 4080 -VIVTGLQDTTVSSDSV-AKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 4137

Query: 2973 LVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS-KDNLIERTQHPKGTE 3020
            +      DSG+YTC   N  G   +S  +   + KD   ++    K +E
Sbjct: 4138 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSE 4186



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 65/299 (21%), Positives = 115/299 (38%), Gaps = 22/299 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P  TL  ++  V  GQ  R    V      +V W  NG ++Q   +       G  TL I
Sbjct: 3601 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 3660

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL-KDK 4632
            L+ +  DSG Y  V  N  GE R D   +            Q +    P  +   L + +
Sbjct: 3661 LDCHTDDSGTYRAVCTNYKGE-RSDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTE 3719

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
              A     + S       +  V+    +     S Y + S +A+  +  + E   E++  
Sbjct: 3720 AYAVPSFKKTSEMEASSSVREVKSQMTETRESLSSY-EHSASAEMKSAALEEKSLEEKST 3778

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
             + +      + T+AA++ +T+P            R + VYEG+ A+F      +  PT+
Sbjct: 3779 TRKI------KTTLAARI-LTKP------------RSMTVYEGESARFSCDTDGEPVPTV 3819

Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             WLR+G ++  +   Q+      +   I +    D G ++     + G+ E    L ++
Sbjct: 3820 TWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 3878



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 110/491 (22%), Positives = 178/491 (36%), Gaps = 38/491 (7%)

Query: 3182 KIEWYHNGQPMRHSTRIKT-VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
            ++ WY +G+ ++ +   +   S  G   L I      D GEYVC    + G   T     
Sbjct: 3975 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 4034

Query: 3241 CYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP----PKFITQIQDVTKLVE 3296
                  ++ E +   S  K  + ++ +    +     + EP    P  +T +QD T +  
Sbjct: 4035 GQAFKSIH-EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSS 4092

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDI---------LY- 3346
               A F  +     +P     W  +GK +  G +Y+   D G   L+I         LY 
Sbjct: 4093 DSVAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYT 4150

Query: 3347 CYEENSG---EYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK-LQTLED 3402
            C  +NS       C  T K  +D T+A    T K + I   +     E   +K L++ E 
Sbjct: 4151 CTVKNSAGSVSSSCKLTIKAIKD-TEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 4209

Query: 3403 SMVRRKDT---SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWN 3459
             M   K     +++EE  K  +      +     E    H E  +T T   + +V  +  
Sbjct: 4210 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEE--ITKTSQASEEVRTH-- 4265

Query: 3460 GKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNII 3519
               +KA S   +  +   ++L+ +     D    L        E        V G    +
Sbjct: 4266 -AEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYG---VSGSDQTL 4321

Query: 3520 LESQLPKGMEGTIDKIAAL-EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFE 3578
               Q     EG +  I+   EG       LT   E  + P F + P    ++E  +  F 
Sbjct: 4322 TIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFT 4381

Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
              +    + S  +EWF N  P+   S V          LEI      D+G YT KA N  
Sbjct: 4382 REIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFR 4439

Query: 3639 GEATVSCKLQV 3649
            G+ + +  L V
Sbjct: 4440 GQCSATASLMV 4450



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 101/468 (21%), Positives = 178/468 (38%), Gaps = 60/468 (12%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRAT 4051
            K+ C++    D + +V W+F  + L +  ++   Y+ G   +    +   D G Y C+  
Sbjct: 2813 KYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 2871

Query: 4052 NLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPP 4111
            N YG D + A +   G    VYD    + MK I++        +    +++E      PP
Sbjct: 2872 NDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKR--------RTDTMRLLER-----PP 2917

Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR-YKLTYD---GMYHF 4167
             F       T   GE  RF   +T HP+P V W  +G  I  G    K T++   G+Y  
Sbjct: 2918 EFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQL 2977

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRT 4227
             I      D  +  V+             L V          L    RP +         
Sbjct: 2978 TINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTL----RPMF--------- 3024

Query: 4228 ETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQ---QSVKRKKNEEYYNKLQEL 4284
                ++     +  + Q V     E++   I  P  +W+   Q +    N E  +  + L
Sbjct: 3025 ----KRLLANAECQEGQSVCF---EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH--EGL 3075

Query: 4285 ENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQ----RYEDNLDQTEEVTEQRVQKK 4340
            +   +     L E T  Y +       +T  ++  Q    RY+    +++E  E+ VQK+
Sbjct: 3076 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 3135

Query: 4341 VTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTE-TTEIEHKAQTQER 4399
            + +  R+ +    T       VAK+   +  V+    ++ K    E   EIE K   +ER
Sbjct: 3136 IDKTLRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEK--KEER 3193

Query: 4400 VVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
             +  P    +P    +K +   + E ++ +  V     P+  +KWY++
Sbjct: 3194 KLRMPYDVPEP----RKYKQTTIEEDQRIKQFV-----PMSDMKWYKK 3232



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 35/146 (23%), Positives = 65/146 (44%), Gaps = 4/146 (2%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP   K  +D     G+  +  C++ GRP P++ W+   +++     +K + ++   H L
Sbjct: 1759 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYK-MSSDGRTHTL 1817

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             +      D GV TC+A N+ GE     +L +++      P +  +        G  + L
Sbjct: 1818 TVMTEEQEDEGVYTCIATNEVGEVETSSKL-LLQATPQFHPGYPLKEKYYGA-VGSTLRL 1875

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPE 536
            +   +G P P +TW   G  ++ N E
Sbjct: 1876 HVMYIGRPVPAMTW-FHGQKLLQNSE 1900



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 82/372 (22%), Positives = 149/372 (40%), Gaps = 58/372 (15%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V +EG ++ + C +E + D + ++ W+F  + L +  +Y+ T++     L +    + D 
Sbjct: 2805 VGEEGGHVKYVCKIE-NYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDD 2863

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
            G Y CK  N  G  ++   L   G + +Y    +   +   +   + +  RL +  RP  
Sbjct: 2864 GTYRCKVVNDYGEDSSYAELFVKGVREVY---DYYCRRTMKKIKRRTDTMRLLE--RP-- 2916

Query: 2904 PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQG---SRF 2960
                   PE+ +P+  +   V G+  ++   V     P+  + WY +G+ ++ G    ++
Sbjct: 2917 -------PEFTLPLYNKTAYV-GE--NVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKY 2966

Query: 2961 KLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTE 3020
               SD G   L +  V   D   YT  A NK GE        C +K   +  T HP  T 
Sbjct: 2967 TFESDKGLYQLTINSVTTDDDAEYTVVARNKYGED------SCKAK---LTVTLHPPPT- 3016

Query: 3021 GLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSM 3080
                    + +LR              P F  +  +  +  EGQ   +E  +  +G    
Sbjct: 3017 --------DSTLR--------------PMFKRLLAN-AECQEGQSVCFEIRV--SGIPPP 3051

Query: 3081 VIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
             ++W  +G+ +     I  ++       L I  T   D+G Y   ATN  G       L+
Sbjct: 3052 TLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQ 3111

Query: 3140 CVDKSKGQKPRF 3151
             V++ + +K  F
Sbjct: 3112 -VERLRYKKQEF 3122



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 72/337 (21%), Positives = 133/337 (39%), Gaps = 44/337 (13%)

Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEY 2315
            EG    + C++E  +D + ++ +Y   + L+++ ++ IT++ G   L ++     D G Y
Sbjct: 2808 EGGHVKYVCKIEN-YDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 2316 SVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKI-RELESAEPFKRPEIPEPVTRQ 2374
              K +N  G  +S   + V     +     R   ++KI R  ++    +RP         
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREVYDYYCR-RTMKKIKRRTDTMRLLERP--------- 2916

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
             P FT PL N      G+   F   +    +P   V W+++ + I+      K + F   
Sbjct: 2917 -PEFTLPLYN-KTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDN-DKKYTF--- 2968

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494
                    + D+G+Y    +++  +              +    ++ E   K +     H
Sbjct: 2969 --------ESDKGLYQLTINSVTTDDDAEYT--------VVARNKYGEDSCKAKLTVTLH 3012

Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
                  P     +P+F ++L   +E  EGQ   +E RV  +  P+L+  W  +G  L +G
Sbjct: 3013 P----PPTDSTLRPMFKRLLAN-AECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLG 3065

Query: 2555 SRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
                  H+   +  L I   +  D G Y   A N AG
Sbjct: 3066 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAG 3102



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 100/478 (20%), Positives = 180/478 (37%), Gaps = 32/478 (6%)

Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITR--KITSTETTEIEHKAQTQ 4397
            K  ++ + P+PS    H K V   + K T  E V    ++   KIT     E   +    
Sbjct: 3907 KSPKRVKSPEPS----HPKAVSPTETKPTPIEKVQHLPVSAPPKITQFLKAEASKEIAKL 3962

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDF 4457
              VVE  V  +K   + K  +  +   H Q  F    DG     I    E+   +   + 
Sbjct: 3963 TCVVESSVLRAKEVTWYKDGKKLKENGHFQ--FHYSADGTYELKINNLTESDQGEYVCEI 4020

Query: 4458 QIHTFSTKSIL-IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
                 ++K+ L  + Q F       + ++E +    K + + V  +   +    I     
Sbjct: 4021 SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV 4080

Query: 4517 TLTA-QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE 4575
             +T  Q+  V+S  + +   K TG       W K+GK +    + K+ E+ G + L I +
Sbjct: 4081 IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 4140

Query: 4576 AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA 4635
                DSG Y C   NSAG     + C +++ A KD      K +      I P K  +V 
Sbjct: 4141 TDTSDSGLYTCTVKNSAGSV--SSSCKLTIKAIKD--TEAQKVSTQKTSEITPQKKAVVQ 4196

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            E    E S K +      +   K  + +   +  + S+      ++ S A   +    K 
Sbjct: 4197 E----EISQKALRSEEIKMSEAKSQEKLALKE--EASKVLISEEVKKSAATSLE----KS 4246

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            + +    + + A++   T  +    + A +    + + EGQ    K  I       ++W+
Sbjct: 4247 IVHEEITKTSQASEEVRTHAE----IKAFS--TQMSINEGQRLVLKANIAG--ATDVKWV 4298

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              G  +  + +++    G++  L I      D G  TC + T  G V+    L +  +
Sbjct: 4299 LNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 4356



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 48/200 (24%), Positives = 80/200 (40%), Gaps = 3/200 (1%)

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMS 4672
            P++      P   E L++  V         CK+ G P P V+WY+ G ++I     +++ 
Sbjct: 2146 PKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQ 2205

Query: 4673 RTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
                 Y  L I+    +D   Y+  A N  G V+  A L+V  P +      L  +  + 
Sbjct: 2206 EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVH 2265

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE-EDTGT 4790
               G+    K   + K  P I W +   LI     +Q+I   +   L+  N  E +D G 
Sbjct: 2266 ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGF 2325

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            +   A    G  + + +L V
Sbjct: 2326 YVVCAKNRFGIDQKTVELDV 2345



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I ++ ++   + G  AQ   Q+ G P P + W++ G+ LI S K+++ +     TL V
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
               ++ D G YT +A N  G + TS  L +++
Sbjct: 1820 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 4/169 (2%)

Query: 1520 RAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPI 1579
            R+ + V ++    R    +  DI    ++     + Q   +R KY            AP 
Sbjct: 3544 RSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSER-KYEVLSQQPFTLDHAPR 3602

Query: 1580 CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDI 1639
             T  +++  +  GQ   F   +   S  T +V+WYHN   L+  S+   TN  G + L+I
Sbjct: 3603 ITLRMRSHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 3660

Query: 1640 MSCLPEDSGTYTCRAINALGE-AVTSGIAIVHSKKSIYLESQHEGALPR 1687
            + C  +DSGTY     N  GE +  + + +     + Y   + +  +PR
Sbjct: 3661 LDCHTDDSGTYRAVCTNYKGERSDYATLDVTGGDYTTYASQRRDEEVPR 3709



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 44/200 (22%), Positives = 81/200 (40%), Gaps = 15/200 (7%)

Query: 1606 DATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG 1665
            D + +V WY   + L++  ++  T   G   L +      D GTY C+ +N  GE  +  
Sbjct: 2822 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 2881

Query: 1666 IAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAEN 1725
               V   + +Y +      + ++ +  DT +         ++ + P FT+P+ +      
Sbjct: 2882 ELFVKGVREVY-DYYCRRTMKKIKRRTDTMR---------LLERPPEFTLPLYNKTAYVG 2931

Query: 1726 QAAHFEARLIPVGDPKLRVEWLRNGVPIEASN---RLTTMHDFGYVALNMKYVNPEDSGT 1782
            +   F   +     P+  V W ++G  I+  +   + T   D G   L +  V  +D   
Sbjct: 2932 ENVRFGVTI--TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAE 2989

Query: 1783 YTCRAINELGEAVTSSTLFV 1802
            YT  A N+ GE    + L V
Sbjct: 2990 YTVVARNKYGEDSCKAKLTV 3009



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 2/105 (1%)

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
            R    ++  +T  +AP   + + ++ T  G    L C++  VG     ++W+  GK +  
Sbjct: 1745 RTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQ 1802

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
              +++ + +     L +++   ED GVYTC ATN++GE  TS  L
Sbjct: 1803 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 4/85 (4%)

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
            TKL  G++A   C+I   P P+  ++WY  GK L    +Y+ S+D     L ++T   ED
Sbjct: 1771 TKL--GEAAQLSCQIVGRPLPD--IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQED 1826

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQS 1938
             G YTC A N +G+  +S +L +Q+
Sbjct: 1827 EGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 53/204 (25%), Positives = 83/204 (40%), Gaps = 19/204 (9%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            D + +V WY+  + L+   ++    + G  IL +      D G Y C+  N+YGE  + A
Sbjct: 2822 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 2881

Query: 3509 SMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI 3568
             + V+G R +            T+ KI   +  + T+  L        PPEFT    +  
Sbjct: 2882 ELFVKGVREV-----YDYYCRRTMKKI---KRRTDTMRLLE------RPPEFTLPLYNKT 2927

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI---NDFGFVILEIGGVYQR 3625
                 +  F    I V+     V W+ +G+ +  G   K     +D G   L I  V   
Sbjct: 2928 AYVGENVRFGV-TITVHPEP-HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 2985

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            D   YT  A N++GE +   KL V
Sbjct: 2986 DDAEYTVVARNKYGEDSCKAKLTV 3009



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 4/95 (4%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGY 827
            RP F R L +  E QEG++  FE +++ +  PT++  W KDG+P++    I  I     Y
Sbjct: 3021 RPMFKRLLAN-AECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDY 3077

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             +L+I     ED G Y V A N  G     A ++V
Sbjct: 3078 YALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 3112



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 3/113 (2%)

Query: 2622 KEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKN 2681
            KE  +    ++ +   +  AP F +  +S + + EGQ+V    ++    +P+ +IEWFKN
Sbjct: 4341 KEGIVKCQYDLTLSKELSDAPAFISQPRSQN-INEGQNVLFTREISG--EPSPEIEWFKN 4397

Query: 2682 GVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + ++  + +  +    + +L I +    DSG YT KA N  G+  +TAS+ +
Sbjct: 4398 NLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 4450



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP     MKD+     +AA    ++  VG P   ++W R G  +  S +     D    
Sbjct: 1758 EAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH 1815

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L +     ED G YTC A NE+GE  TSS L +Q+
Sbjct: 1816 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 49/228 (21%), Positives = 89/228 (39%), Gaps = 15/228 (6%)

Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448
            +EG    + C+ I   D + +V W+   + +E+S +   T++ G   + +  +   D+G 
Sbjct: 2807 EEGGHVKYVCK-IENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 2865

Query: 2449 YMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKP 2508
            Y C+  N  GE              +  +      MKKI++  +    R  E   EF  P
Sbjct: 2866 YRCKVVNDYGEDSSYAELFVKGVREV-YDYYCRRTMKKIKR--RTDTMRLLERPPEFTLP 2922

Query: 2509 IFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG---SRFRTTHDFGF 2565
            ++ +        + G++  +   +    +P +   WY +G ++K G    ++    D G 
Sbjct: 2923 LYNKT------AYVGENVRFGVTITVHPEPHV--TWYKSGQKIKPGDNDKKYTFESDKGL 2974

Query: 2566 VTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRP 2613
              L INSV  +D   Y   A N+ G                 D  +RP
Sbjct: 2975 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 3022



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 1/102 (0%)

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTF 4462
            P   +  P+F + +      E +   FE+   G P P +KW ++  P+   P+ + IH  
Sbjct: 3015 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEG 3074

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR 4504
                 L IR    ED+  +   A N  G+  C A+L VE  R
Sbjct: 3075 LDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLR 3116



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 1/84 (1%)

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH-NHTTLRVRNTQKSD 332
            N++ QEG    F++++SG P P + W K+GQ L      EII    ++  L +R+T   D
Sbjct: 3030 NAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPED 3089

Query: 333  SGHYTLLAENPNGCIVTSGYLAVE 356
            +G+Y + A N  G      +L VE
Sbjct: 3090 TGYYRVTATNTAGSTSCQAHLQVE 3113



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FIS   +    EG N+ F   +  S +P+ +IEWF NN P+   +    +   +  SL+I
Sbjct: 4363 FISQPRSQNINEGQNVLFTREI--SGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 4420

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
             +    DSG YT KA N +G  + + SL
Sbjct: 4421 RNASVSDSGKYTIKAKNFRGQCSATASL 4448



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 49/204 (24%), Positives = 84/204 (41%), Gaps = 12/204 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P   K+M+       E A+   +  G PLP IKWYR    +  S  +++ +      L +
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                 ED  V+  +A N  G  + S+ L+++   +        P + L  +      G  
Sbjct: 1820 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ------FHPGYPLKEKYYGAV-GST 1872

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ--DSGKYECVA 4588
            +RL     G +P+      +G+K+  +  N  +E    YT L+++   +   +GKY+   
Sbjct: 1873 LRLHVMYIG-RPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQL 1931

Query: 4589 INSAGEARCDAECVVSLPATKDKP 4612
             N  G    DA   V +    DKP
Sbjct: 1932 SNVFGTV--DAILDVEIQDKPDKP 1953



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 2/74 (2%)

Query: 2926 GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
            G+   L  Q+  +  PD+K  WY  GK L Q  ++K++SD    TL ++   + D G+YT
Sbjct: 1774 GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 2986 CKAYNKRGEAFTSS 2999
            C A N+ GE  TSS
Sbjct: 1832 CIATNEVGEVETSS 1845



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 53/216 (24%), Positives = 83/216 (38%), Gaps = 17/216 (7%)

Query: 650  EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEY 709
            EGG + +  +IE   D + ++ W    + +E S ++   +  G   L +  +   D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 710  TCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQR 769
             C+ V+  G   + A L V             E   Y  +     K + +        + 
Sbjct: 2867 RCKVVNDYGEDSSYAELFV---------KGVREVYDYYCR-RTMKKIKRRTDTMRLLERP 2916

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG---RPITASSRITSIFNFG 826
            P+F  PL +      G N  F   +T   +P   V WYK G   +P     + T   + G
Sbjct: 2917 PEFTLPLYN-KTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 2973

Query: 827  YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               L I  +  +D   YTV A NK GE    A + V
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 3009



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 2/80 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G    F   V+  + P   + W+HNG +++   +   T+  G + L+IL  + +DSGTY 
Sbjct: 3615 GQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 3672

Query: 2184 CKATNKLGEAVNTCTLKVAG 2203
               TN  GE  +  TL V G
Sbjct: 3673 AVCTNYKGERSDYATLDVTG 3692



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 5/134 (3%)

Query: 354  AVESPTESYVQDQRSQY--ITDTQQRE--TEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            ++ S  ES+V+   S +  I++  Q E  T + ++   + + P+   +  D  + EGK+ 
Sbjct: 4514 SMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVL 4573

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHALMITNVTLSDSGVVTCVAR 468
               C  TG P PEVTW    R+I      +  + N      L+I +V   D G+ T    
Sbjct: 4574 TVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLG 4633

Query: 469  NKSGETAFQCRLNV 482
            N+ G  +    +++
Sbjct: 4634 NEFGSDSATVNIHI 4647



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 3/95 (3%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            S E P    +++DVT  + G++A    ++V    PD+K  W+  GK+L    +Y+   D 
Sbjct: 1756 SGEAPGIRKEMKDVTTKL-GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDG 1812

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
                L ++   +E+ G Y C+ATN++G   T + L
Sbjct: 1813 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 43/186 (23%), Positives = 76/186 (40%), Gaps = 8/186 (4%)

Query: 3054 FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGT 3113
            F   + I+EGQ    +A++    D    ++W  NG  +  S   R   +     L I   
Sbjct: 4271 FSTQMSINEGQRLVLKANIAGATD----VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQA 4326

Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173
               D G  +C +  K G  +    L  + K     P F +  ++ + + +GQ+  F   +
Sbjct: 4327 SHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDAPAFISQPRS-QNINEGQNVLFTREI 4384

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                +P  +IEW+ N  P+  S+ +          L+I      DSG+Y  +A N  G+ 
Sbjct: 4385 S--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQC 4442

Query: 3234 FTRATI 3239
               A++
Sbjct: 4443 SATASL 4448



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 25/89 (28%), Positives = 41/89 (46%)

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
            AP   +    +  + GE   L+ + VG P P I W + G  +I + + ++ +DG   TL 
Sbjct: 1759 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 1818

Query: 550  IPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +   +  D   Y C A N  G   T ++L
Sbjct: 1819 VMTEEQEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            +  AP  T  ++S+ ++  GQ+      V+ +  P  +++W+ NGV L   +++  T   
Sbjct: 3597 LDHAPRITLRMRSH-RVPCGQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTS 3653

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G++TL I     DDSG Y    TN  GE    A++ +
Sbjct: 3654 GVLTLEILDCHTDDSGTYRAVCTNYKGERSDYATLDV 3690



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 36/147 (24%), Positives = 68/147 (46%), Gaps = 9/147 (6%)

Query: 3391 EGGLEKLQTLEDSMVR-RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
            EG L  +   ++ +V+ + D ++ +E   AP F +     +N+ EG+N  F   ++   +
Sbjct: 4331 EGILTCISKTKEGIVKCQYDLTLSKELSDAPAF-ISQPRSQNINEGQNVLFTREIS--GE 4387

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P+ ++EW+ N   +   S            LEI      DSG+Y  +A N  G+   TAS
Sbjct: 4388 PSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATAS 4447

Query: 3510 MKV-----QGKRNIILESQLPKGMEGT 3531
            + V     +  R ++L +     ++G+
Sbjct: 4448 LMVLPLVEEPSREVVLRTSGDTSLQGS 4474



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 2/94 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P FI   +S    EG  + F   I   G+P+ +IEW KN   I  SS  +        SL
Sbjct: 4361 PAFISQPRSQNINEGQNVLFTREIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSL 4418

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTP 730
            ++ + ++ DSG+YT +A +  G     A L V P
Sbjct: 4419 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLP 4452



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P   K +K+     G    L   +  V  P   ++WY  G+ + Q  ++K + D    
Sbjct: 1758 EAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH 1815

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
             L ++    ED G Y C ATN VGE  T+S + + A
Sbjct: 1816 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 22/70 (31%), Positives = 39/70 (55%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            ++ P  +++WY NG  L++ S+   T+  G +TL+++D +  DSG Y     N +GE   
Sbjct: 3625 QSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSD 3684

Query: 2998 SSTVYCTSKD 3007
             +T+  T  D
Sbjct: 3685 YATLDVTGGD 3694



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 38/144 (26%), Positives = 62/144 (43%), Gaps = 8/144 (5%)

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
            +++ T  +I+ +   LA + +   +   V EG+  RF C   G P P VTW    R +  
Sbjct: 3774 EEKSTTRKIKTT---LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGRVLST 3830

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
               H++   +       I++V  SD G  + V  N  G+   +  L  I+K +V      
Sbjct: 3831 SARHQVTTTKY-KSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL-TIQKARVTEKAVT 3888

Query: 495  ERFSTLNVREGEPVVLNARAVGTP 518
               S   V+  EP V +  AV +P
Sbjct: 3889 ---SPPRVKSPEPRVKSPEAVKSP 3909



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 32/118 (27%), Positives = 55/118 (46%), Gaps = 7/118 (5%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-FG 1766
            T  P+F   + +    E Q+  FE R+  +  P L+  W ++G P+     +  +H+   
Sbjct: 3019 TLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLD 3076

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ----SKASLQLESQHESALQK 1820
            Y AL+++   PED+G Y   A N  G     + L V+     K   + + +HE  +QK
Sbjct: 3077 YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQK 3134



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 3/108 (2%)

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT 1087
            +Y   +++   +   PR    ++ ++++  GQ+  F   V  QS  T  V+WY NG ++ 
Sbjct: 3586 KYEVLSQQPFTLDHAPRITLRMR-SHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQ 3642

Query: 1088 SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             +++I   +  G + L+I     +DSG Y  V  N  GE    A++ V
Sbjct: 3643 ESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYATLDV 3690



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/74 (32%), Positives = 38/74 (51%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P  +V+W++NG +L    +    +  G++ L+IL C+ ++SG Y  V TN  G  S  A 
Sbjct: 3628 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYAT 3687

Query: 3372 LKCTSKENLILDSQ 3385
            L  T  +     SQ
Sbjct: 3688 LDVTGGDYTTYASQ 3701



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 4/135 (2%)

Query: 1803 QSKASLQLESQHESALQKIQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLSEGQS 1861
            +  A   + S++ES    ++  + S R Y+        ++ APR   ++    ++  GQ+
Sbjct: 3559 ERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH-RVPCGQN 3617

Query: 1862 AHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
              +   ++    P   V+WY NG  LQ   +   +N  G   L+IL  + +DSG Y    
Sbjct: 3618 TRFILNVQS--KPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVC 3675

Query: 1922 INNLGQAVSSIRLNV 1936
             N  G+      L+V
Sbjct: 3676 TNYKGERSDYATLDV 3690



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 32/107 (29%), Positives = 49/107 (45%), Gaps = 2/107 (1%)

Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
            KY+  S Q   +  AP  T+ M+  RV   Q   F   +     P   V+W  NGV ++ 
Sbjct: 3586 KYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQE 3643

Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            S+++   +  G + L +   + +DSGTY     N  GE    +TL V
Sbjct: 3644 SSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYATLDV 3690



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 2/69 (2%)

Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
           ++ GA  +  V +SG P P +TW K G  L  +++  I TT +++ L V    + D+G Y
Sbjct: 685 IRAGASLRLMVSVSGRPPPVITWSKQGIDL--ASRAIIDTTESYSLLIVDKVNRYDAGKY 742

Query: 337 TLLAENPNG 345
           T+ AEN +G
Sbjct: 743 TIEAENQSG 751



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 34/144 (23%), Positives = 63/144 (43%), Gaps = 5/144 (3%)

Query: 1946 SQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIKNAEVTEGHPVHLEATLTPV 2004
            S++ES    ++  +   R    +    F ++  P+    +++  V  G        L   
Sbjct: 3568 SRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRF--ILNVQ 3625

Query: 2005 NDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            + PT  V+WY NG  +Q+  +   T   G + L+IL  + +D+GTY    TN  GE   +
Sbjct: 3626 SKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE--RS 3683

Query: 2065 SSVKVDAKSGLYLDTLDEQRLKKI 2088
                +D   G Y     ++R +++
Sbjct: 3684 DYATLDVTGGDYTTYASQRRDEEV 3707



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 5/114 (4%)

Query: 3674 KLEETLHKREEITIEDE--KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731
            K ++T  ++ E+  +      + PR T+ ++ +  VP G    F   V+    PT  + W
Sbjct: 3578 KTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH-RVPCGQNTRFILNVQ--SKPTAEVKW 3634

Query: 3732 FHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +HNG      S++H  N  G + L+I   +  D+G Y    TN  G  +  A +
Sbjct: 3635 YHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYATL 3688



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 3/105 (2%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            PR    +R +  V  G+   F   V+    P   +++YHNG  LQ +++ H T   G ++
Sbjct: 3601 PRITLRMR-SHRVPCGQNTRFILNVQS--KPTAEVKWYHNGVELQESSKIHYTNTSGVLT 3657

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQR 2346
            L+I  C  +D+G Y     N  G  +   ++ VT        SQR
Sbjct: 3658 LEILDCHTDDSGTYRAVCTNYKGERSDYATLDVTGGDYTTYASQR 3702



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+   +++SH V   +  RF   V+ K  P   ++WY NG  L    +       G ++L
Sbjct: 3601 PRITLRMRSHRVPCGQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTSGVLTL 3658

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            +IL  + +DSG Y     N  GE    AT+
Sbjct: 3659 EILDCHTDDSGTYRAVCTNYKGERSDYATL 3688



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 6/127 (4%)

Query: 4058 ETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLP 4117
            E K+ +  T +    Y+      MKS   + E     + T  ++     AR     ++ P
Sbjct: 3740 EVKSQMTETRESLSSYEHSASAEMKSAA-LEEKSLEEKSTTRKIKTTLAAR----ILTKP 3794

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYD 4176
             ++TV EGE ARF C   G P P V WL  G  +   +R+++T       F+I   +  D
Sbjct: 3795 RSMTVYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASD 3854

Query: 4177 TGKIEVI 4183
             G   V+
Sbjct: 3855 EGNYSVV 3861



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 6/106 (5%)

Query: 3544 TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLI--PVNDSSMRVEWFHNGKPLL 3601
            T  ++  +  SG  P       D+      +A   C+++  P+ D    ++W+  GK L+
Sbjct: 1746 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD----IKWYRFGKELI 1801

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
               + K  +D     L +    Q D G+YTC ATN  GE   S KL
Sbjct: 1802 QSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 69/294 (23%), Positives = 119/294 (40%), Gaps = 28/294 (9%)

Query: 4218 YDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEY 4277
            Y +  Q QR   E E     R V   Q + +++ EL   + KE     ++S K+ + +  
Sbjct: 3414 YRQPKQRQRIMAEREDEELLRPVTTTQHLSEYKSELD-FMSKE-----EKSRKKSRRQRE 3467

Query: 4278 YNKLQELENEQVIKESRLRESTHQYA--IPGDKVTSNTVAKSMAQRYE------DNLDQT 4329
              ++ E+E E  I +   RES+   +  +   +  S T  + M    E         ++ 
Sbjct: 3468 VTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEY 3527

Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAK-QKQTQKEVVGDKEITRKITSTETT 4388
            E+ TE+R       +PR P P  S     E  +++ ++  + ++    E  +    T+ T
Sbjct: 3528 EDDTERRSPTPERTRPRSPSPVSS-----ERSLSRFERSARFDIFSRYESMKAALKTQKT 3582

Query: 4389 EIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN 4448
              E K    E + + P      P  T +M+  RV   +  RF +    +P   +KWY   
Sbjct: 3583 S-ERK---YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG 3638

Query: 4449 FPIKNSPDFQIHTFSTKSILI--IRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
              ++ S   +IH  +T  +L   I     +DS  + AV  N  G     A L V
Sbjct: 3639 VELQESS--KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYATLDV 3690



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G N  F  NV+    PT +++W+ N   L   ++   T+    ++L+I   + +DSG Y 
Sbjct: 3615 GQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 3672

Query: 2848 CKATNSKGSATTSGSLRCTG 2867
               TN KG  +   +L  TG
Sbjct: 3673 AVCTNYKGERSDYATLDVTG 3692



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            + ++  K G+     C +     P +K  W+   K L    +YK + D    +L +    
Sbjct: 1766 MKDVTTKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEE 1823

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
            +ED G+YTC ATN  G   TS  L
Sbjct: 1824 QEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F+++  NA   +G +  FE ++ G P P + W +   PL       +  +E     +L
Sbjct: 3022 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEI-IHEGLDYYAL 3080

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
             I+   P D G Y  TA N  G   C  ++Q E
Sbjct: 3081 HIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 3113



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   L  Q+  R  P++K  W++ G  L    + K + D    TL++ +   +D G+YT
Sbjct: 1774 GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 2717 CKATNLLGEAVSTASIKIE 2735
            C ATN +GE  +++ + ++
Sbjct: 1832 CIATNEVGEVETSSKLLLQ 1850



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 3/81 (3%)

Query: 1057 EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD-FGYVALDIASVRAEDSGV 1115
            EGQS  FE RV      T+  +W  +G+ ++    I+  H+   Y AL I     ED+G 
Sbjct: 3035 EGQSVCFEIRVSGIPPPTL--KWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGY 3092

Query: 1116 YTVVARNAAGEAQLSASMTVE 1136
            Y V A N AG     A + VE
Sbjct: 3093 YRVTATNTAGSTSCQAHLQVE 3113



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P    ++K  T +  E  +  C++  +  P   I+WYR GK L    +Y+   D    +L
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD--IKWYRFGKELIQSRKYKMSSDGRTHTL 1817

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             ++    ED G Y C A N+ GE  T + +  +  P
Sbjct: 1818 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATP 1853



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 4407 PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP-IKNSPDFQIHTF-ST 4464
            P + P F ++++   V     A    +  G P P++KWYR+    I +   ++I  F   
Sbjct: 2151 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 2210

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
               LII  V  +D+ V+   A N+GG+   +A+L VE
Sbjct: 2211 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 2247



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 5/103 (4%)

Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP-IKTGHRFR 1360
            + D+ + QAP F   L N+     +N  L C++   G     V+W+  GK  I  G ++R
Sbjct: 2147 KSDVPI-QAPHFKEELRNLNVRYQSNATLVCKV--TGHPKPIVKWYRQGKEIIADGLKYR 2203

Query: 1361 -PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
               ++  Y  L + SV  +D+ VY  +ATNQ G    + +L V
Sbjct: 2204 IQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 2246



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/93 (34%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHT-DGGA 545
            + AP F E    LNVR      L  +  G P P + W + G  II +  + RI    GG 
Sbjct: 2152 IQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGY 2211

Query: 546  STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              L I      DA  YQ  A N  GS +  A L
Sbjct: 2212 HQLIIASVTDDDATVYQVRATNQGGSVSGTASL 2244



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            PR T  +++   +  GQ+  F   V     P  +++WYHNG  ++ S++I   +  G + 
Sbjct: 3601 PRITLRMRS-HRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 3657

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
            L+I      DSG Y     N  GE    AT++  G
Sbjct: 3658 LEILDCHTDDSGTYRAVCTNYKGERSDYATLDVTG 3692



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
           ++ G+D      + G P P++ W K  + L    K  +  T    T  ++   +SDSG Y
Sbjct: 286 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKY 345

Query: 337 TLLAENPNGCIVTSGYLAV-ESP 358
           TL  +N +G    S  + V +SP
Sbjct: 346 TLTVKNASGTKAVSVMVKVLDSP 368



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +++G   +  + + G P P   W K GQ +  S +  I T+  HT L ++   + DSG Y
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTY 1432

Query: 337  TLLAENPNG 345
             L+ EN  G
Sbjct: 1433 DLVLENKCG 1441



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P   +  K+     G  A+   ++ G P P + W R    L++  KY M  + +T  +++
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819

Query: 132  LIKQIGPGDEGEYTCTARNQYGE 154
            + ++    DEG YTC A N+ GE
Sbjct: 1820 MTEE--QEDEGVYTCIATNEVGE 1840



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 2/69 (2%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G+ A   C++  VG P   ++W+R  K +  S +   + D    ++T+     EDEGVY 
Sbjct: 1774 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 2451 CRASNLLGE 2459
            C A+N +GE
Sbjct: 1832 CIATNEVGE 1840



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 3/68 (4%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH-EIITTHNHTTLRVRN-TQKSDSGHYT 337
            G     ++  SG P P +TW K GQ LI++N H ++I T + T+L   N  ++ D+G Y 
Sbjct: 2269 GEVVSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYV 2327

Query: 338  LLAENPNG 345
            + A+N  G
Sbjct: 2328 VCAKNRFG 2335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 3/89 (3%)

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
            + G+ P     ++++   K G++A   C +V    PD+K  WY  G+ +  S + K  SD
Sbjct: 1755 TSGEAPGIRKEMKDVT-TKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSD 1811

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                 L +   +  D G Y C A N+ GE
Sbjct: 1812 GRTHTLTVMTEEQEDEGVYTCIATNEVGE 1840



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 3/134 (2%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P+I  + R+ ++  G + +F + +   P   V W+ NG  L  S+K     T    TL +
Sbjct: 3601 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 3660

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
             +    DSG Y  +  N  G    S Y  ++     Y     SQ   +   R     +  
Sbjct: 3661 LDCHTDDSGTYRAVCTNYKG--ERSDYATLDVTGGDYT-TYASQRRDEEVPRSVFPELTR 3717

Query: 386  SEKALAPQFVKVCQ 399
            +E    P F K  +
Sbjct: 3718 TEAYAVPSFKKTSE 3731



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 2122 KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
            K G+ A   C++  +  P   I W+  G+++    +Y+ + D     L ++    ED G 
Sbjct: 1772 KLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 1829

Query: 2182 YMCKATNKLGEAVNTCTL 2199
            Y C ATN++GE   +  L
Sbjct: 1830 YTCIATNEVGEVETSSKL 1847



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 6/91 (6%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLI--PVSDATLKVEWYHNNKPLKSGSRFTETNNFG 1633
            +AP     +K+V  K G+ A    +++  P+ D    ++WY   K L    ++  +++  
Sbjct: 1758 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD----IKWYRFGKELIQSRKYKMSSDGR 1813

Query: 1634 FVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
               L +M+   ED G YTC A N +GE  TS
Sbjct: 1814 THTLTVMTEEQEDEGVYTCIATNEVGEVETS 1844



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 4/122 (3%)

Query: 246  GESD-VQISTEID-RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
            GES+  +IS  I  +S  P+  P   ++ RN  ++  ++A    +++G+P+P V W++ G
Sbjct: 2133 GESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQG 2192

Query: 304  QRLI-NSNKHEIIT-THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTES 361
            + +I +  K+ I      +  L + +    D+  Y + A N  G +  +  L VE P + 
Sbjct: 2193 KEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKI 2252

Query: 362  YV 363
            ++
Sbjct: 2253 HL 2254



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSI---EASSRFTSIFRFG 692
            PP+F +PL + TA  G  + F   I    +P   + W K+GQ I   +   ++T     G
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 2973

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
               L + S+   D  EYT  A +  G    KA L VT
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 3010



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR---KKAPLVECNKYSMRYNEQTG 127
            PP F     N     G N +F   +  +P P V+W +   K  P     KY+  +    G
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT--FESDKG 2973

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
               L I  +   D+ EYT  ARN+YGE  C
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSC 3003



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 12/172 (6%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGFIALDIDYIYA 3762
            N +  EG  V F+ RV  +  PT++  W  +G+P + G  +  +++   + AL I     
Sbjct: 3030 NAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLP 3087

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCS----AKRDIVLESQLPQGMSGEKIKELERGRISD 3818
             D G Y   ATN  GS +  A +        K++   + +  + +  +  K L    I  
Sbjct: 3088 EDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILS 3147

Query: 3819 APKEEPIVSTPPKFITQ--IKSHTVEESEGVRFECRV---EPKEDPKLRIEW 3865
              +  P+     + + +  +       ++ V+ E R+   E KE+ KLR+ +
Sbjct: 3148 GTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLRMPY 3199



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 19/50 (38%), Positives = 29/50 (58%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            ++W++NG  ++ S +I      G++ LEIL   T DSGTY    TN  G+
Sbjct: 3632 VKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 3681



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 48/245 (19%), Positives = 84/245 (34%), Gaps = 19/245 (7%)

Query: 522  ITWQKDGVPIIPNPELRIHTDG-GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
            +TW KDG  +  N   + H    G   L I     SD   Y C      G++ T  +   
Sbjct: 3976 VTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 4035

Query: 581  XXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFI 640
                      K +H  + +K+                  +  P  P    + +   P  +
Sbjct: 4036 QAF-------KSIH-EKVSKISETKKSDQKTTESTV-TRKTEPKAP----EPISSKPVIV 4082

Query: 641  VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLS 700
              L+  T        F   ++  G+P     W K+G++I    ++      G   L++  
Sbjct: 4083 TGLQDTTVSSDSVAKFA--VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 4140

Query: 701  LNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQE 760
             +  DSG YTC   ++ G   +   L +     I+ T     + Q   ++    K   QE
Sbjct: 4141 TDTSDSGLYTCTVKNSAGSVSSSCKLTI---KAIKDTEAQKVSTQKTSEITPQKKAVVQE 4197

Query: 761  SIEEQ 765
             I ++
Sbjct: 4198 EISQK 4202



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 12/133 (9%)

Query: 2366 EIPEPVTR------QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI 2419
            EI EP+T       Q P F + L+N+ N++    A   C++   G P   V+W+R  K I
Sbjct: 2139 EISEPITPKSDVPIQAPHFKEELRNL-NVRYQSNATLVCKV--TGHPKPIVKWYRQGKEI 2195

Query: 2420 EDSSRITKTHDF--GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE 2477
                   +  +F  GY  + I+ V D+D  VY  RA+N  G               I L 
Sbjct: 2196 IADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL- 2254

Query: 2478 TQHPEGMKKIQKL 2490
             +  EGM  +  L
Sbjct: 2255 PKTLEGMGAVHAL 2267



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 768  QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-- 825
            Q P F   L++L    +  NA    ++T    P   V+WY+ G+ I A      I  F  
Sbjct: 2153 QAPHFKEELRNLNVRYQS-NATLVCKVT--GHPKPIVKWYRQGKEIIADGLKYRIQEFKG 2209

Query: 826  GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            GY  L I  +  +DA  Y VRA N+ G    TAS+ V
Sbjct: 2210 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 2246



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G+N  F   L   S PT  V+WY +G  +  SS+I      G ++L I+    +D+G+Y 
Sbjct: 3615 GQNTRFI--LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 3672

Query: 845  VRAVNKLGEAISTASIRVAARSTVT 869
                N  GE    A++ V      T
Sbjct: 3673 AVCTNYKGERSDYATLDVTGGDYTT 3697



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/61 (36%), Positives = 30/61 (49%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V+W+HNG  L   S++   N  G + LEI   +  D+G Y    TN  GE +    L V 
Sbjct: 3632 VKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYATLDVT 3691

Query: 3651 G 3651
            G
Sbjct: 3692 G 3692



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
            NI EGQ   F   +   G+P+ ++EWF+N   I  SS ++ +      S+ I +    D 
Sbjct: 4371 NINEGQNVLFTREIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 4428

Query: 2447 GVYMCRASNLLGE 2459
            G Y  +A N  G+
Sbjct: 4429 GKYTIKAKNFRGQ 4441



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTG 4178
            VT + GE A+  C++ G P P + W   G  ++   +YK++ DG  H   +    Q D G
Sbjct: 1769 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEG 1828



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 4/110 (3%)

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
            + +V  QAP F   ++++ V     A    ++   G PK  V+W R G  I A      +
Sbjct: 2147 KSDVPIQAPHFKEELRNLNVRYQSNATLVCKV--TGHPKPIVKWYRQGKEIIADGLKYRI 2204

Query: 1763 HDF--GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             +F  GY  L +  V  +D+  Y  RA N+ G    +++L V+  A + L
Sbjct: 2205 QEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL 2254



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 2/80 (2%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            G+N  F   L     P  +V+WY NG  L+  S+       G + LEI   + +DSG Y 
Sbjct: 3615 GQNTRFI--LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 3672

Query: 3495 CRAYNNYGEAVTTASMKVQG 3514
                N  GE    A++ V G
Sbjct: 3673 AVCTNYKGERSDYATLDVTG 3692



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G +   +  + G P P + WT+    L  C K S++Y  +    + +IK     D G+YT
Sbjct: 289 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKR--ATAVIKFCDRSDSGKYT 346

Query: 146 CTARNQYGEAICSVYIQ 162
            T +N  G    SV ++
Sbjct: 347 LTVKNASGTKAVSVMVK 363



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/106 (31%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
           S+Y     + E  ERIEI +  LA    K    R    G   R    V+GRP P +TW  
Sbjct: 653 SEYSESIAEIEPVERIEIPDLELADDLKKTVTIR---AGASLRLMVSVSGRPPPVITW-- 707

Query: 428 NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
             +Q  D  +  I+        L++  V   D+G  T  A N+SG+
Sbjct: 708 -SKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGK 752



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 20/66 (30%), Positives = 31/66 (46%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
            G   +  + ++G P P  +WF  G +L  S +  + T      L +R T   D+G YTL 
Sbjct: 980  GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 1039

Query: 340  AENPNG 345
             +N  G
Sbjct: 1040 LKNVTG 1045



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 48/184 (26%), Positives = 80/184 (43%), Gaps = 10/184 (5%)

Query: 3774 NKWGSATTTA-KITCSAKRDIVLESQLPQGMSGEKIK-ELERGRISD--APKEEPIVSTP 3829
            NKW S TT   + T  + ++++   +    +  E +  E E   IS+   PK +  +  P
Sbjct: 2096 NKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAP 2155

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYR-TVYDMGFV 3887
              F  ++++  V         C+V     PK  ++WYR GK ++  G +YR   +  G+ 
Sbjct: 2156 -HFKEELRNLNVRYQSNATLVCKVTGH--PKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 2212

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQME 3947
             L I  V  +D+  Y  RA N  G     A++   ++P  I   +   GM    AL    
Sbjct: 2213 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTLEGMGAVHALRGEV 2271

Query: 3948 ATIK 3951
             +IK
Sbjct: 2272 VSIK 2275



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 4091 EASWQVTPEQVVEESKARCP-PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            E+ W    E +  +S      P F      + V     A   C+VTGHPKP V W   G 
Sbjct: 2134 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 2193

Query: 4150 TIV-NGSRYKL-TYDGMYH 4166
             I+ +G +Y++  + G YH
Sbjct: 2194 EIIADGLKYRIQEFKGGYH 2212



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 3403 SMVRRKDTSVEEE--KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
            S  RR   S++ +   G+AP     + ++   + GE A    ++     P++K  WY  G
Sbjct: 1741 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTT-KLGEAAQLSCQIVGRPLPDIK--WYRFG 1797

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            K L    +++   D     L +     ED G Y C A N  GE  T++ + +Q
Sbjct: 1798 KELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 1850



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/60 (28%), Positives = 32/60 (53%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            ++WY  GK++  + + +   D     L + +   ED GVYT +A N  GE + S+ + ++
Sbjct: 1791 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 1850



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 19/53 (35%), Positives = 28/53 (52%)

Query: 2538 PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            P+   +WY NGVEL+  S+   T+  G +TL+I     +D+G Y     N  G
Sbjct: 3628 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKG 3680



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 82/413 (19%), Positives = 159/413 (38%), Gaps = 55/413 (13%)

Query: 1017 LEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMT 1076
            LEK    E+ ++ S+ +EE     +   F   +     I EGQ    +A +   +D    
Sbjct: 4243 LEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMS----INEGQRLVLKANIAGATD---- 4294

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            V+W  NG ++T++   +         L I      D G+ T +++   G  +    +T+ 
Sbjct: 4295 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 4354

Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFV-----EPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
               S   + I +   +     +   F      EP  +IE    + P+ +   S+   +S 
Sbjct: 4355 KELSDAPAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPISI---SSNVSISR 4411

Query: 1192 GKNIH-LECRLEPMGDP---TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADT 1247
             +N++ LE R   + D    T++ + F    S T         +    + +++  TS DT
Sbjct: 4412 SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEP--SREVVLRTSGDT 4469

Query: 1248 ---GEYTVRAV-----------NHLGSAHTSAIVRV------------IERSDIVTDTQN 1281
               G ++ ++V           +   S+  S++  +            ++ S +   + +
Sbjct: 4470 SLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSS 4529

Query: 1282 EQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQT 1341
               I  +  LE +   +K ++  I  +  P+      +I   EG  + + C     G+ T
Sbjct: 4530 FMGISNMTQLESST--SKMLKAGIRGIP-PKIEALPSDISIDEGKVLTVACAF--TGEPT 4584

Query: 1342 MRVEWFCNGKPIKTGH--RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
              V W C G+ I +    RF      D   L ++ V  +D G+YT    N+ G
Sbjct: 4585 PEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 4637



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 2/79 (2%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V +G  I  +  I GKP P  +W K  + I        S T  E  L I EA   D G Y
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTE--LVIKEADRGDSGTY 1432

Query: 4694 KCVAYNSAGRVTVAAKLKV 4712
              V  N  G+  V  K++V
Sbjct: 1433 DLVLENKCGKKAVYIKVRV 1451



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/190 (21%), Positives = 75/190 (39%), Gaps = 11/190 (5%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            +G  P      KD+     G+ A     ++  G     I+W+  GK +  S + +     
Sbjct: 1756 SGEAPGIRKEMKDVTT-KLGEAAQLSCQIV--GRPLPDIKWYRFGKELIQSRKYKMSSDG 1812

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L ++  +  D G Y+C ATN+ G+ E S KL          P+F       E    
Sbjct: 1813 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL-----LLQATPQFHPGYPLKEKYYG 1867

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQNHDSGE 3221
               +     V+ +  P   + W+H  + +++S    I+    +  +V+     + H +G+
Sbjct: 1868 AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTH-AGK 1926

Query: 3222 YVCRAYNKYG 3231
            Y  +  N +G
Sbjct: 1927 YKVQLSNVFG 1936



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTLRVRNTQ-KSDSGHYT 337
            G+  +  V   G P P +TWF +GQ+L+ NS    I  T ++T L ++N Q K+ +G Y 
Sbjct: 1870 GSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYK 1928

Query: 338  LLAENPNGCI 347
            +   N  G +
Sbjct: 1929 VQLSNVFGTV 1938



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/164 (24%), Positives = 67/164 (40%), Gaps = 10/164 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEA---SHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            TG    +++W+  GK I A    +RI+  +  G   L I      D+  Y  RATN+ G 
Sbjct: 2179 TGHPKPIVKWYRQGKEIIADGLKYRIQE-FKGGYHQLIIASVTDDDATVYQVRATNQGGS 2237

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD-DPDMKIEWYHNGQ 3190
               +  LE    +K   P+    +  +  L+ G+    +   +P    PD  I W     
Sbjct: 2238 VSGTASLEVEVPAKIHLPKTLEGMGAVHALR-GEVVSIK---IPFSGKPDPVITWQKGQD 2293

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAY-TQNHDSGEYVCRAYNKYGED 3233
             + ++   + +    F  L      +  D+G YV  A N++G D
Sbjct: 2294 LIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGID 2337



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYT 4679
            PP+I     D  + EG+ +  +C   G+P P V W  G + I   +   F +  T D  T
Sbjct: 4555 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 4614

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            L I +   +D G Y     N  G  +    + +
Sbjct: 4615 LIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 4647



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 17/130 (13%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-FGYIS 695
            P F   L +    EG  + FE R+  +  PT+K  W K+GQ +        I     Y +
Sbjct: 3022 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYA 3079

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L +     +D+G Y   A +  G    +A L V             E L+Y +Q E  SK
Sbjct: 3080 LHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV-------------ERLRYKKQ-EFKSK 3125

Query: 756  YQHQESIEEQ 765
             +H+  +++Q
Sbjct: 3126 EEHERHVQKQ 3135



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHA 449
            AP+     +   V  G+ TRF   V  +P  EV W+ N  ++++  + KI   N SG   
Sbjct: 3600 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQE--SSKIHYTNTSGVLT 3657

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            L I +    DSG    V  N  GE +    L+V
Sbjct: 3658 LEILDCHTDDSGTYRAVCTNYKGERSDYATLDV 3690



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 1459 GQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGI 1516
            G+     C++   P+ D    ++W++ G+ +    +++   D     L ++    ED G+
Sbjct: 1774 GEAAQLSCQIVGRPLPD----IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 1829

Query: 1517 YTCRAVNLVGTDEVSCRLTCRST 1539
            YTC A N VG  E S +L  ++T
Sbjct: 1830 YTCIATNEVGEVETSSKLLLQAT 1852



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 17/54 (31%), Positives = 30/54 (55%)

Query: 2406 PTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            PT +V+W+ N   +++SS+I  T+  G +++ I     +D G Y    +N  GE
Sbjct: 3628 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 3681



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/74 (28%), Positives = 35/74 (47%)

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
           + +R G  +VL+A   G P P+I W K    +    ++ +   G  +T  I     SD+ 
Sbjct: 284 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 343

Query: 560 WYQCTAQNVAGSTA 573
            Y  T +N +G+ A
Sbjct: 344 KYTLTVKNASGTKA 357



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 3/95 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P    E+KD +    G      C++  VG P   I W+  G+      +    +D     
Sbjct: 1760 PGIRKEMKD-VTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT 1816

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
            L +      D G YTC ATN+ G   T++K+   A
Sbjct: 1817 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 19/64 (29%), Positives = 31/64 (48%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAV 725
            PT +++W  NG  ++ SS+       G ++L++L  +  DSG Y     +  G     A 
Sbjct: 3628 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYAT 3687

Query: 726  LHVT 729
            L VT
Sbjct: 3688 LDVT 3691



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/147 (19%), Positives = 60/147 (40%), Gaps = 8/147 (5%)

Query: 1794 AVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGP 1853
            ++++ ++    ++ +++ S     +  + QLE S+       ++  +   P  I  L   
Sbjct: 4509 SMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM----LKAGIRGIPPKIEALPSD 4564

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH--RYRTSNDFGFAALDILTVYG 1911
              + EG+     C     P P   V W   G+ + S    R+   N      L I+ V  
Sbjct: 4565 ISIDEGKVLTVACAFTGEPTPE--VTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQK 4622

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            +D G YT    N  G   +++ ++++S
Sbjct: 4623 QDGGLYTLSLGNEFGSDSATVNIHIRS 4649



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/79 (26%), Positives = 32/79 (40%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            +  G  +     + GKP P + W KGDK +   +   +  T    T  I      D G Y
Sbjct: 286  IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKY 345

Query: 4694 KCVAYNSAGRVTVAAKLKV 4712
                 N++G   V+  +KV
Sbjct: 346  TLTVKNASGTKAVSVMVKV 364



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 8/116 (6%)

Query: 48  MTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR 107
           M+   ES  + +P+   R   P   + + + K      G + +    + G P PV++W++
Sbjct: 652 MSEYSESIAEIEPVE--RIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK 709

Query: 108 KKAPLVECNKYSMRYNEQTGDVSLLI-KQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           +   L      S    + T   SLLI  ++   D G+YT  A NQ G+   +V ++
Sbjct: 710 QGIDLA-----SRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 760



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 15/42 (35%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP   +LP  ++++EG+     C  TG P P V W   G  I
Sbjct: 4555 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 4596



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 40/159 (25%), Positives = 55/159 (34%), Gaps = 5/159 (3%)

Query: 3629 LYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE 3688
            L  CKA        V+ K  V       L       F+   ++ + + E       +T++
Sbjct: 898  LEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQ 957

Query: 3689 DEKPNPP-RFTVEIKDNIDVPEGGPVHFDCRVEPV-GDPTMRIDWFHNGRPFATGSRVHT 3746
            D +  P    +   +  I VP G PV     V P+ G P     WF  G       RV  
Sbjct: 958  DLRVLPTIDLSTMPQKTIHVPAGRPVEL---VIPIAGRPPPAASWFFAGSKLRESERVTV 1014

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                    L I     RD GEYT    N  G+   T K+
Sbjct: 1015 ETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTLETIKV 1053



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 2/107 (1%)

Query: 59   QPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNK 117
            +PIT         P F++  +N       NA    K+ G+P P+V W R+ K  + +  K
Sbjct: 2142 EPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 2201

Query: 118  YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            Y ++   + G   L+I  +   D   Y   A NQ G    +  ++ E
Sbjct: 2202 YRIQ-EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 2247



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRG-NPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P+  QI  +A   +GG+ K+  K+   + +  V+W      L    KY + Y +  G   
Sbjct: 2796 PVSGQIM-HAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED--GVAI 2852

Query: 131  LLIKQIGPGDEGEYTCTARNQYGE 154
            L +K I   D+G Y C   N YGE
Sbjct: 2853 LYVKDITKLDDGTYRCKVVNDYGE 2876



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG--GAS 546
            + PK     S +++ EG+ + +     G PTP +TW   G  I    + R H +     +
Sbjct: 4554 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 4613

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            TL I   +  D   Y  +  N  GS +    ++
Sbjct: 4614 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIH 4646



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
            +PP       ++++  G+++ +    TG    +V W   G+K+  Q   R  I   D   
Sbjct: 4554 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 4613

Query: 4570 TLLILEAYPQDSGKYECVAINSAG 4593
            TL+I++   QD G Y     N  G
Sbjct: 4614 TLIIMDVQKQDGGLYTLSLGNEFG 4637



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNK 470
           D  V G+P P++ W   D+++  D   K+ +  +G  A  +I     SDSG  T   +N 
Sbjct: 295 DAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 352

Query: 471 SGETAFQCRLNVIE 484
           SG  A    + V++
Sbjct: 353 SGTKAVSVMVKVLD 366



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 2648 LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
            LK    +  G  + L   V  R  P   I W K G+ L + A + +T  + L  L ++ +
Sbjct: 679  LKKTVTIRAGASLRLMVSVSGRPPP--VITWSKQGIDLASRAIIDTTESYSL--LIVDKV 734

Query: 2708 RNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               D+G YT +A N  G+  +T  +K+ D
Sbjct: 735  NRYDAGKYTIEAENQSGKKSATVLVKVYD 763



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            +K VT   G       +I  VG P   I+W + G+ +  S ++         +L +++  
Sbjct: 1766 MKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEE 1823

Query: 703  IQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
             +D G YTC A +  G  ET  K +L  TP+
Sbjct: 1824 QEDEGVYTCIATNEVGEVETSSKLLLQATPQ 1854



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G  A    Q+  V  P   ++WY+ G+ +  S +     +    +L +M    ED G YT
Sbjct: 1774 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRY 880
              A N++GE + T+S ++  ++T     G P + +Y
Sbjct: 1832 CIATNEVGE-VETSS-KLLLQATPQFHPGYPLKEKY 1865



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 11/120 (9%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT-GARLK-STFDF 2697
            QAP F   L++ +   +  +  L  +V     P +K  W++ G  +   G + +   F  
Sbjct: 2153 QAPHFKEELRNLNVRYQS-NATLVCKVTGHPKPIVK--WYRQGKEIIADGLKYRIQEFKG 2209

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLH-PDSLDRIGAL 2756
            G   L I S+ +DD+ +Y  +ATN  G    TAS+++E     +   +H P +L+ +GA+
Sbjct: 2210 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-----VPAKIHLPKTLEGMGAV 2264



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 3/81 (3%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD-FGLVTLSINSLRNDDSGI 2714
            EGQ V  E +V     P LK  W K+G  L+ G  ++   +      L I     +D+G 
Sbjct: 3035 EGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGY 3092

Query: 2715 YTCKATNLLGEAVSTASIKIE 2735
            Y   ATN  G     A +++E
Sbjct: 3093 YRVTATNTAGSTSCQAHLQVE 3113



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 19/69 (27%), Positives = 30/69 (43%)

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
            L     PT  V+W+HNG  +   S+       G + L+I+   + D+G Y     N+ G 
Sbjct: 3622 LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 3681

Query: 1261 AHTSAIVRV 1269
                A + V
Sbjct: 3682 RSDYATLDV 3690



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 6/78 (7%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            QGG  +    ++G P P+  WT++     + +K +M    +T    L+IK+   GD G Y
Sbjct: 1377 QGGVIRLTIPIKGKPFPICKWTKEGQ---DISKRAMIATSET-HTELVIKEADRGDSGTY 1432

Query: 145  TCTARNQYGEAICSVYIQ 162
                 N+ G+   +VYI+
Sbjct: 1433 DLVLENKCGKK--AVYIK 1448



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 2/81 (2%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            E  +  CQ+  VG P   ++W+  GK L+   ++    D     +       ED G Y C
Sbjct: 1775 EAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC 1832

Query: 4049 RATNLYGMDETKAVIKTTGKP 4069
             ATN  G  ET + +     P
Sbjct: 1833 IATNEVGEVETSSKLLLQATP 1853



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
            ++  T+  AP+ +  + +     G N      +Q     T  V+W+ NG  ++   +   
Sbjct: 3592 QQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHY 3649

Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
                  + L++L  + +DSG Y    TN  GE
Sbjct: 3650 TNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 3681



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
            EGQ+  +   +   G+PS   EW+ N + + + S    +      +L+I +   +D+G Y
Sbjct: 4374 EGQNVLFTREIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 4431

Query: 2582 MCKAINRAG 2590
              KA N  G
Sbjct: 4432 TIKAKNFRG 4440



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 2/72 (2%)

Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           T+ +R G  + L     G P P ITW K G+ +       I T    S L + +    DA
Sbjct: 682 TVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTTESYSLLIVDKVNRYDA 739

Query: 559 AWYQCTAQNVAG 570
             Y   A+N +G
Sbjct: 740 GKYTIEAENQSG 751



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 3/97 (3%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            S + P  +  +KD ++ K G  A    ++  +G     ++W + G+ +  S +     + 
Sbjct: 1756 SGEAPGIRKEMKD-VTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDG 1812

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                LT+ +    D G YTC A N +G+  TS+ L +
Sbjct: 1813 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLL 1849



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+   L C++  +G P   ++W+  G+ +    ++K   D     L ++     D G YT
Sbjct: 1774 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 1252 VRAVNHLGSAHTSA 1265
              A N +G   TS+
Sbjct: 1832 CIATNEVGEVETSS 1845



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 41/163 (25%), Positives = 65/163 (39%), Gaps = 10/163 (6%)

Query: 4357 GKEVHVAKQKQTQKEVVGDKE--ITRKITSTETTEIEHKAQTQERVVEGPVK-----PSK 4409
            GKE+     K   +E  G     I   +T  + T  + +A  Q   V G        P+K
Sbjct: 2192 GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 2251

Query: 4410 P--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTFSTKS 4466
               P   + M        E    ++ F G+P P+I W +    I N+  +Q I T S  S
Sbjct: 2252 IHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTS 2311

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
            ++    V  +D+  +   A+NR G  + +  L V +     RG
Sbjct: 2312 LVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG 2354



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/66 (27%), Positives = 33/66 (50%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E   +P  +IEW+ N   +   S   ++      +L++ +    DSG YT KA N RG+ 
Sbjct: 4383 EISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQC 4442

Query: 2996 FTSSTV 3001
              ++++
Sbjct: 4443 SATASL 4448



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 4/62 (6%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EGQ + L+A +   TD    ++W  NGV LT     +        TL+I    + D GI 
Sbjct: 4279 EGQRLVLKANIAGATD----VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGIL 4334

Query: 2716 TC 2717
            TC
Sbjct: 4335 TC 4336



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 50   TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
            TQ+ESS  +  + AG  G   PP  E +  +    +G          G PTP V+W+   
Sbjct: 4537 TQLESSTSKM-LKAGIRG--IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWS-CG 4592

Query: 110  APLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
               +   +    + E T D+ +L+I  +   D G YT +  N++G    +V I
Sbjct: 4593 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 4645



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLNDFG 3751
            PP+    +  +I + EG  +   C     G+PT  + W   GR   +    R H  N   
Sbjct: 4555 PPKIEA-LPSDISIDEGKVLTVACAF--TGEPTPEVTWSCGGRKIHSQEQGRFHIENTDD 4611

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               L I  +  +D G YT    N++GS + T  I
Sbjct: 4612 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 4645



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ- 4579
            + V + +G  +RL   V+G  P  + W K G  +       I++   +Y+LLI++   + 
Sbjct: 681  KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL---ASRAIIDTTESYSLLIVDKVNRY 737

Query: 4580 DSGKYECVAINSAGE 4594
            D+GKY   A N +G+
Sbjct: 738  DAGKYTIEAENQSGK 752



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
            V  G+       + GRP P  +WF    ++R+  + ++ V      A L I   T+ D+G
Sbjct: 977  VPAGRPVELVIPIAGRPPPAASWFFAGSKLRE--SERVTVETHTKVAKLTIRETTIRDTG 1034

Query: 462  VVTCVARNKSGETAFQCRLNVIEK 485
              T   +N +G T    ++ +++K
Sbjct: 1035 EYTLELKNVTGTTLETIKVIILDK 1058



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/60 (28%), Positives = 25/60 (41%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            W   G  +  S R+T   +     LTI+  T+ D G YT    N  G    +  + I+ K
Sbjct: 999  WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTLETIKVIILDK 1058



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
            V +G + R    + G+P+P   W    +    D + + ++  S  H  L+I      DSG
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQ----DISKRAMIATSETHTELVIKEADRGDSG 1430

Query: 462  VVTCVARNKSGETAFQCRLNVI 483
                V  NK G+ A   ++ VI
Sbjct: 1431 TYDLVLENKCGKKAVYIKVRVI 1452



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
            R  +   G+P P+ KW +E   I  S    I T  T + L+I++    DS  +  V EN+
Sbjct: 1382 RLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENK 1439

Query: 4489 GG 4490
             G
Sbjct: 1440 CG 1441



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHV-RDEDEGVYMCRASNLLG 2458
            +G P   + WF  +KL+++S  IT  +   Y  + + +V R    G Y  + SN+ G
Sbjct: 1880 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG 1936



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 1/98 (1%)

Query: 4714 QPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
            QP   D+ P +T  +R   V  GQ  +F   + SK    ++W   G  + E+      + 
Sbjct: 3593 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 3652

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                 L I + + +D+GT+    T   G+    A L V
Sbjct: 3653 SGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYATLDV 3690



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PR   R +S   V  GQ+  F   ++  +    +V+W+ NG  +    +    +  G + 
Sbjct: 3601 PRITLRMRS-HRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 3657

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVG 1526
            L+I+D   +DSG Y     N  G
Sbjct: 3658 LEILDCHTDDSGTYRAVCTNYKG 3680



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/74 (27%), Positives = 30/74 (40%)

Query: 4003 PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAV 4062
            P  +V+W+ NG  L   ++       G + +     + +DSG Y    TN  G     A 
Sbjct: 3628 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYAT 3687

Query: 4063 IKTTGKPGIVYDSQ 4076
            +  TG     Y SQ
Sbjct: 3688 LDVTGGDYTTYASQ 3701



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/74 (27%), Positives = 30/74 (40%)

Query: 499  TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
            T++V  G PV L     G P P  +W   G  +  +  + + T    + L I      D 
Sbjct: 974  TIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 1033

Query: 559  AWYQCTAQNVAGST 572
              Y    +NV G+T
Sbjct: 1034 GEYTLELKNVTGTT 1047



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            VG P    +WY  G EL    +++ + D    TL + +    D G+Y C A N  G
Sbjct: 1784 VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 1839



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 9/114 (7%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PK +  + +      E V  +     K DP   I W +   L+ +   Y+ +    F SL
Sbjct: 2255 PKTLEGMGAVHALRGEVVSIKIPFSGKPDPV--ITWQKGQDLIDNNGHYQVIVTRSFTSL 2312

Query: 3890 DILY-VYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEA 3942
                 V  +D+G Y+  A N FG D     +    +PD       PRG+K S+A
Sbjct: 2313 VFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPD------PPRGVKVSDA 2360


>AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle
            preferentially expressed protein protein.
          Length = 3094

 Score =  121 bits (291), Expect = 7e-26
 Identities = 89/314 (28%), Positives = 146/314 (46%), Gaps = 18/314 (5%)

Query: 4501 EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIR 4559
            + +R    G   PP+F ++  + +V  GQ V +  +V G  KP+ V WL+N + V+PD R
Sbjct: 727  QNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPV-VSWLRNRQPVRPDQR 785

Query: 4560 NKILE-EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKA 4618
                E E G   L IL A   D+G Y C A+N  G  +C+A   V       +  P++++
Sbjct: 786  RFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV-------RAHPESRS 838

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY-FQMSRTADE 4677
                  ++ PL+D  V  G+   F C + G     V W    +L++P+    +M     +
Sbjct: 839  L----AVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRK 894

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
              L ++    +D G Y C    +   +T +A+L V +P  A     L  L D+ V EG+ 
Sbjct: 895  CKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV-RPSLAPLFTRL--LEDVEVLEGRA 951

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
            A+F  +I+    P + W   G  + E+ + ++  +G    L I +   ED G +   A  
Sbjct: 952  ARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVN 1011

Query: 4798 AAGQVETSAKLVVK 4811
              GQ   SA+L V+
Sbjct: 1012 THGQAHCSAQLYVE 1025



 Score =  111 bits (266), Expect = 8e-23
 Identities = 101/390 (25%), Positives = 159/390 (40%), Gaps = 51/390 (13%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP F   +    V E +     +   GEP P++ W R   P++  PD +      +  L 
Sbjct: 739  PPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVR--PDQRRFAEEAEGGLC 796

Query: 4470 -IRQVFVE--DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             +R +  E  D+  +   A N  G  +C A L V          ++ P      Q+V+V 
Sbjct: 797  RLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAP-----LQDVDVG 851

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT-LLILEAYPQDSGKYE 4585
            +G++   +  V G   ++V WL  G+ +QP +    +  DG    LL+   +  DSG Y 
Sbjct: 852  AGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYT 911

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C    +  E  C A   V         +P     +  P     L+D  V EG+A  F CK
Sbjct: 912  CKLSTAKDELTCSARLTV---------RP-----SLAPLFTRLLEDVEVLEGRAARFDCK 957

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            I G P P V W      ++ S+  ++ +    ++L I+    EDEG Y   A N+ G+  
Sbjct: 958  ISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAH 1017

Query: 4706 VAAKLKVTQPDQADNLPA--------------------------LTPLRDIVVYEGQPAQ 4739
             +A+L V +P  A + P+                          L PL+D+ V   + A 
Sbjct: 1018 CSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAM 1077

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQM 4769
             + Q+T    PTI W   G  I  + D +M
Sbjct: 1078 LECQVTGLPYPTISWFHNGHRIQSSDDRRM 1107



 Score =  105 bits (253), Expect = 3e-21
 Identities = 61/208 (29%), Positives = 100/208 (48%), Gaps = 2/208 (0%)

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
            P+     +     + APP     L D+ V EGQ +  S ++ G+P P V W +  + ++P
Sbjct: 723  PSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRP 782

Query: 4666 -SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
              + F          LRI  A   D G Y C A N  G     A+L+V    ++ +L  L
Sbjct: 783  DQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVL 842

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDFQMIHEGNNAVLLIGNT 4783
             PL+D+ V  G+ A F+  +       + WL  G L+ P     +M  +G    LL+ + 
Sbjct: 843  APLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSV 902

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +E+D+G +TC+ +TA  ++  SA+L V+
Sbjct: 903  HEDDSGVYTCKLSTAKDELTCSARLTVR 930



 Score =  103 bits (248), Expect = 1e-20
 Identities = 77/289 (26%), Positives = 120/289 (41%), Gaps = 30/289 (10%)

Query: 4458 QIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT 4517
            ++H    K  L++  V  +DS V+            CSA L V           + P FT
Sbjct: 887  KMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPS--------LAPLFT 938

Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577
               ++V V  G+  R D K++GT P  V W   G  ++     ++ ++ G ++L I    
Sbjct: 939  RLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVG 998

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP--------------- 4622
             +D G Y   A+N+ G+A C A+  V  P T     P +K    P               
Sbjct: 999  SEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASG-PSSKLEKMPSIPEEPEQGELERLS 1057

Query: 4623 -PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
             P+ + PL+D  V   +     C++ G P PT+ W+     I+ S   +M++  D + L 
Sbjct: 1058 IPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLV 1117

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-----PDQADNLPALT 4725
                 P+  G YK V  N  G+    A L VT      PD A  + A+T
Sbjct: 1118 FPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVT 1166



 Score = 96.7 bits (230), Expect = 2e-18
 Identities = 82/321 (25%), Positives = 124/321 (38%), Gaps = 34/321 (10%)

Query: 261  GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
            G  +PP       +  ++EG D    +++ G P+P V+W +N Q                
Sbjct: 735  GSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQP--------------- 779

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
                VR  Q+         AE   G +     LA E     +      + + +   R+ E
Sbjct: 780  ----VRPDQRR-------FAEEAEGGLCRLRILAAERGDAGFYT---CKAVNEYGARQCE 825

Query: 381  ERIEISEKALAPQFVKVC--QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
             R+E+     +     +   QD DV  G+M  F+C V G    EV W    R ++     
Sbjct: 826  ARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLK 885

Query: 439  KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498
              +  +     L++T+V   DSGV TC       E     RL V      +AP F     
Sbjct: 886  CKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV---RPSLAPLFTRLLE 942

Query: 499  TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             + V EG     + +  GTP P +TW   G P+  +  LR+  DGG  +L I    + D 
Sbjct: 943  DVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDE 1002

Query: 559  AWYQCTAQNVAGSTATRARLY 579
              Y  +A N  G     A+LY
Sbjct: 1003 GLYAVSAVNTHGQAHCSAQLY 1023



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 98/441 (22%), Positives = 179/441 (40%), Gaps = 23/441 (5%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            E  R   S  ++++E      E   +G ++    P F + +Q   V   ++A  E +  G
Sbjct: 1025 EEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTG 1084

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
             P P I W+     I++S D ++  +     L+   V  + + V+ +V  N+ G A C A
Sbjct: 1085 LPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYA 1144

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
            +L V +        +VP       Q V VT G++V L    T   P  +    +   +  
Sbjct: 1145 HLYVTD--------VVPGPPDGAPQVVAVT-GRMVTL----TWNPPRSLDMAIDPDSLTY 1191

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
             +++++L  D    L+     P  +       +              S P+   +P    
Sbjct: 1192 TVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLL 1251

Query: 4617 K---AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV-QWYKGDKLIKPSKYFQMS 4672
            +        P +++      V EGQ    +          V +  +G  L   +  +++S
Sbjct: 1252 EHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEARAGVYELS 1311

Query: 4673 RTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
            +  D +Y LRI      D G   C A N  G  T +  L++ +  + +++     + D+ 
Sbjct: 1312 QPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESI-----MEDVE 1366

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
            V  G+ A+F   +  K  P I W ++  L+ E+     ++E N   L++ +T  +D G +
Sbjct: 1367 VGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVY 1426

Query: 4792 TCRATTAAGQVETSAKLVVKS 4812
            TC A   AG+V   A+L V S
Sbjct: 1427 TCTAQNLAGEVSCKAELAVHS 1447



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 61/221 (27%), Positives = 95/221 (42%), Gaps = 21/221 (9%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V+PS  P+FT+ ++   V E   ARF+ +  G P P++ W     P++ S + ++     
Sbjct: 929  VRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGG 988

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG--------GIVP--- 4513
               L I  V  ED  ++A  A N  G A CSA L VEE R    G          +P   
Sbjct: 989  LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEP 1048

Query: 4514 ----------PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                      P F    Q++ V   +   L+ +VTG     + W  NG ++Q     ++ 
Sbjct: 1049 EQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMT 1108

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            +    + L+     PQ +G Y+ V  N  G+A C A   V+
Sbjct: 1109 QYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVT 1149



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 63/227 (27%), Positives = 101/227 (44%), Gaps = 12/227 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP+FT  ++D+ V E +AA F+ ++   G P   V W   G P+E S  L    D G  +
Sbjct: 934  APLFTRLLEDVEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 991

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829
            L++ +V  ED G Y   A+N  G+A  S+ L+V+   +    S   S L+K+  + +   
Sbjct: 992  LHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRT--AASGPSSKLEKMPSIPEEPE 1049

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
                E + +     P F+  L    ++   + A  EC++   P P   + W+ NG  +QS
Sbjct: 1050 QGELERLSI-----PDFLRPLQ-DLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQS 1101

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
                R +       L    V  + +G Y     N LG+A     L V
Sbjct: 1102 SDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 1148



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 80/339 (23%), Positives = 125/339 (36%), Gaps = 22/339 (6%)

Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           P+  P      +N  +  GAD   +  ++ NP P+V+W K+G  L +  +  +       
Sbjct: 589 PLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERH 648

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-------------------SPTESY 362
           TL +R  + +D+G Y   A N  G    +  L V                    SP E +
Sbjct: 649 TLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEF 708

Query: 363 VQDQRSQYITDTQQRETEERIEISEK-ALAPQFVKV-CQDRDVTEGKMTRFDCRVTGRPY 420
            +   +   T T +    +    S+  + AP   KV   D+ V EG+      RV G P 
Sbjct: 709 PEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPK 768

Query: 421 PEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
           P V+W  N + +R D        E G   L I      D+G  TC A N+ G    + RL
Sbjct: 769 PVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARL 828

Query: 481 NVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN-PELRI 539
            V    +  +   +     ++V  GE  +      G     + W   G  + P   + ++
Sbjct: 829 EVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKM 888

Query: 540 HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           H DG    L +      D+  Y C            ARL
Sbjct: 889 HFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARL 927



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 3/223 (1%)

Query: 262  PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            P   P   +   + ++ EG  A+F  ++SG P P VTW   G  +  S    +       
Sbjct: 931  PSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLH 990

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
            +L + +    D G Y + A N +G    S  L VE P  +      S+        E  E
Sbjct: 991  SLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTA-ASGPSSKLEKMPSIPEEPE 1049

Query: 382  RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            + E+ E+   P F++  QD +V   K    +C+VTG PYP ++WF N  +I+   + + +
Sbjct: 1050 QGEL-ERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRR-M 1107

Query: 442  VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
                  H L+   V    +GV   V  NK G+ A    L V +
Sbjct: 1108 TQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTD 1150



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/322 (22%), Positives = 141/322 (43%), Gaps = 24/322 (7%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIE-ASHRIRTVYAFGMVVLEILGTKTT 3116
            VD+  G++A +E   +  G   + ++W   G+ ++ A  + +  +      L +      
Sbjct: 848  VDVGAGEMALFEC--LVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHED 905

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            DSG Y+C+ +    +   S +L          P FT  ++++E L +G++A F+C +   
Sbjct: 906  DSGVYTCKLSTAKDELTCSARLTV---RPSLAPLFTRLLEDVEVL-EGRAARFDCKISGT 961

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P   + W H G PM  S  ++   D G   L IA+  + D G Y   A N +G+    
Sbjct: 962  PPP--VVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQ---- 1015

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP---PKFITQIQDVTK 3293
               +C  +  +Y+E  +  +     +LE +    ++ P     E    P F+  +QD+ +
Sbjct: 1016 --AHCSAQ--LYVEEPRTAASGPSSKLEKMPSIPEE-PEQGELERLSIPDFLRPLQDL-E 1069

Query: 3294 LVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSG 3353
            +   + A  E ++  +  P   + WF+NG ++      R      +  L       +++G
Sbjct: 1070 VGLAKEAMLECQVTGLPYP--TISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAG 1127

Query: 3354 EYECVATNKLGRDSTKANLKCT 3375
             Y+ V  NKLG+ +  A+L  T
Sbjct: 1128 VYKSVIANKLGKAACYAHLYVT 1149



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 63/250 (25%), Positives = 96/250 (38%), Gaps = 12/250 (4%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
           +E + AP F      + V  G  V+L       P P+++W KDG  +     L +  +G 
Sbjct: 587 EEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGE 646

Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRL-----HLPRPT 599
             TL +  A+A+DA  Y  TA N  G     A L              +     +L  P 
Sbjct: 647 RHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPE 706

Query: 600 KVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETR 659
           +                   + R     G +     PP F V L   +  EG  +    R
Sbjct: 707 EFPEPGETWPRTPTMKPSPSQNRRSSDTGSK----APPTFKVSLMDQSVREGQDVIMSIR 762

Query: 660 IEPVGDPTMKIEWLKNGQSIEASS-RFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718
           ++  G+P   + WL+N Q +     RF      G   L +L+    D+G YTC+AV+  G
Sbjct: 763 VQ--GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYG 820

Query: 719 VAETKAVLHV 728
             + +A L V
Sbjct: 821 ARQCEARLEV 830



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 64/226 (28%), Positives = 96/226 (42%), Gaps = 12/226 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P+F + L +   V EG+    +C++   G P   V W H G  +      +   D G  +
Sbjct: 935  PLFTRLLEDVE-VLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 991

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I H  S D G Y V AVN  G AH SA + V E     +   ++  +E++  + +   
Sbjct: 992  LHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSK--LEKMPSIPEEPE 1049

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            + +  R     +  P F R L ++E        LEC  Q  G     + WF NG  I++ 
Sbjct: 1050 QGELER-----LSIPDFLRPLQDLEVGLAKEAMLEC--QVTGLPYPTISWFHNGHRIQSS 1102

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
               R     D   L   +V P+ +GVY     N+LG+A     L V
Sbjct: 1103 DDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 1148



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 61/229 (26%), Positives = 97/229 (42%), Gaps = 17/229 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP+ T  L++VE+ EG+ A F+ ++         V W H   P++         + G  +
Sbjct: 934  APLFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHS 991

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696
            L I     ED G Y   A+N  G+A        H    +Y+E     A    ++LE    
Sbjct: 992  LHIAHVGSEDEGLYAVSAVNTHGQA--------HCSAQLYVEEPRTAASGPSSKLEKMPS 1043

Query: 1697 YQRHSAQDEV-ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
                  Q E+     P F  P++D+ V   + A  E ++   G P   + W  NG  I++
Sbjct: 1044 IPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQV--TGLPYPTISWFHNGHRIQS 1101

Query: 1756 SN--RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            S+  R+T   D     L    V P+ +G Y     N+LG+A   + L+V
Sbjct: 1102 SDDRRMTQYRDVH--RLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 1148



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 69/277 (24%), Positives = 116/277 (41%), Gaps = 22/277 (7%)

Query: 1679 SQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVG 1738
            SQ +G   R    E  S    + +  E   +APVF +P++++ VA    A    + I   
Sbjct: 561  SQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPG--ADVLLKCIITA 618

Query: 1739 DPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
            +P  +V W ++G  + +  RL    +     L ++     D+G+Y   A NELG+A  ++
Sbjct: 619  NPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAA 678

Query: 1799 TLFVQSKAS-------LQLESQHESALQKIQQLEDS---------SRYQRREDVEVAVNQ 1842
            +L V+   S       +  + ++ S  ++  +  ++         S  Q R   +     
Sbjct: 679  SLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKA 738

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQSGHRYRTSNDFGF 1901
             P F   L   + + EGQ      R++  P P   V W  N + V     R+    + G 
Sbjct: 739  PPTFKVSLMDQS-VREGQDVIMSIRVQGEPKP--VVSWLRNRQPVRPDQRRFAEEAEGGL 795

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
              L IL     D+G YTCKA+N  G      RL V++
Sbjct: 796  CRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRA 832



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 70/253 (27%), Positives = 106/253 (41%), Gaps = 18/253 (7%)

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
            S  E+  + P F  PLQ++  +  G +   +  +T  ++P  +V W+KDG  + +  R+ 
Sbjct: 584  SAGEEPLEAPVFEIPLQNV-VVAPGADVLLKCIIT--ANPPPQVSWHKDGSALRSEGRLL 640

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA-------RSTVTAD-- 871
                    +L +   RA DAGSY   A N+LG+A   AS+ V          S +T+D  
Sbjct: 641  LRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEE 700

Query: 872  -LGIPEQRRYIEKT-XXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHF 929
             L  PE+     +T                     S   P FK  + DQ S++EG     
Sbjct: 701  YLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQ-SVREGQDVIM 759

Query: 930  EARLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
              R++  G+    V WL++ +PV     R       G   L I +    DAG YTC+A N
Sbjct: 760  SIRVQ--GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVN 817

Query: 989  AIGQATTSANLTI 1001
              G     A L +
Sbjct: 818  EYGARQCEARLEV 830



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 71/261 (27%), Positives = 110/261 (42%), Gaps = 18/261 (6%)

Query: 1805 KASLQLESQHE--SALQ--KIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQ 1860
            K  L L S HE  S +   K+   +D      R  V  ++  AP F T+L    ++ EG+
Sbjct: 894  KCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSL--APLF-TRLLEDVEVLEGR 950

Query: 1861 SAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920
            +A ++C+I   P P   V W   G  ++     R   D G  +L I  V  ED G Y   
Sbjct: 951  AARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVS 1008

Query: 1921 AINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQF 1980
            A+N  GQA  S +L V+   +    S   S LEK+  + ++       Q +   +  P F
Sbjct: 1009 AVNTHGQAHCSAQLYVEEPRTAA--SGPSSKLEKMPSIPEEPE-----QGELERLSIPDF 1061

Query: 1981 GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDIL 2040
             +P+++ EV       LE  +T +  PT  + W+ NG  +Q     + T       L   
Sbjct: 1062 LRPLQDLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQSSDDRRMTQYRDVHRLVFP 1119

Query: 2041 YAYAEDTGTYMCKATNAVGEA 2061
                +  G Y     N +G+A
Sbjct: 1120 AVGPQHAGVYKSVIANKLGKA 1140



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 59/216 (27%), Positives = 95/216 (43%), Gaps = 10/216 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++ EV EG     +  ++    P   V W   G P+++    +   D G  +L
Sbjct: 935  PLFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHSL 992

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             I +  +ED G Y   A N  G+A  ++ + V+        +    +L+K+  +   E P
Sbjct: 993  HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPR--TAASGPSSKLEKMPSIP--EEP 1048

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
            +  E E+    P FL  L  LE +     A  EC+V  +  P+ TI WFHNG +I++   
Sbjct: 1049 EQGELERL-SIPDFLRPLQDLE-VGLAKEAMLECQVTGL--PYPTISWFHNGHRIQSSDD 1104

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
             R T       L       + +G Y     NKLG+A
Sbjct: 1105 RRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKA 1140



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 70/260 (26%), Positives = 110/260 (42%), Gaps = 30/260 (11%)

Query: 1970 DDSFV------VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023
            DDS+V      +E P F  P++N  V  G  V L+  +T   +P  +V W+ +G  ++  
Sbjct: 579  DDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITA--NPPPQVSWHKDGSALRSE 636

Query: 2024 HRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV--DAKSGLYLD--T 2079
             R     +     L +  A A D G+YM  ATN +G+A   +S+ V     +  +    T
Sbjct: 637  GRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPIT 696

Query: 2080 LDEQRLKKIQEL----EKYER-----PKPIEEEQPGQR-----PVFLTALTSLENLKEGD 2125
             DE+ L   +E     E + R     P P +  +         P F  +L   ++++EG 
Sbjct: 697  SDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMD-QSVREGQ 755

Query: 2126 RAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-YRTTHDFGYVALDILYTYAEDSGTYMC 2184
                  RV+   +P   + W  N Q +R   R +    + G   L IL     D+G Y C
Sbjct: 756  DVIMSIRVQ--GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTC 813

Query: 2185 KATNKLGEAVNTCTLKVAGH 2204
            KA N+ G       L+V  H
Sbjct: 814  KAVNEYGARQCEARLEVRAH 833



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 79/363 (21%), Positives = 147/363 (40%), Gaps = 30/363 (8%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            +P  ++ W+ +G  L    R  L ++    TL L +    D+G Y   A N+ G+A  ++
Sbjct: 619  NPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAA 678

Query: 3000 TV--------------YCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTG 3045
            ++                + ++ L    + P+  E   +   ++ S   +  +  D  + 
Sbjct: 679  SLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPS-PSQNRRSSDTGSK 737

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG- 3104
             PP F     D   + EGQ      S+   G+   V+ W  N + +    R     A G 
Sbjct: 738  APPTFKVSLMD-QSVREGQ--DVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGG 794

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +  L IL  +  D+G Y+C+A N++G  +   +LE     + +       +Q+++ +  G
Sbjct: 795  LCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVD-VGAG 853

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHS-TRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            + A FEC V      D++++W   G+ ++ +  + K   D     L +      DSG Y 
Sbjct: 854  EMALFECLV--AGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYT 911

Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPK 3283
            C+      E      + C  +  V   SL P     + ++E L+G   +     S  PP 
Sbjct: 912  CKLSTAKDE------LTCSARLTV-RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPP 964

Query: 3284 FIT 3286
             +T
Sbjct: 965  VVT 967



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/217 (26%), Positives = 89/217 (41%), Gaps = 27/217 (12%)

Query: 389  ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
            +LAP F ++ +D +V EG+  RFDC+++G P P VTW      + +  N + L  + G H
Sbjct: 932  SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLR-LRQDGGLH 990

Query: 449  ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-------------IEK---------- 485
            +L I +V   D G+    A N  G+     +L V             +EK          
Sbjct: 991  SLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQ 1050

Query: 486  ---EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542
               E++  P F+     L V   +  +L  +  G P P I+W  +G  I  + + R+   
Sbjct: 1051 GELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQY 1110

Query: 543  GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
                 L  P      A  Y+    N  G  A  A LY
Sbjct: 1111 RDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLY 1147



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 62/235 (26%), Positives = 105/235 (44%), Gaps = 23/235 (9%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S R+ V  P ++P    T L     V EG+ A F+C++     P   + + H G  ++ +
Sbjct: 924  SARLTVR-PSLAP--LFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEES 978

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALG--HCTSAISMTVTAKGSIISESQR 2346
                +  D G  SL I H   ED G Y+V A+N  G  HC++ + +    + +    S +
Sbjct: 979  ENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE-EPRTAASGPSSK 1037

Query: 2347 PEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDP 2406
             E +  I E       +R  IP+        F +PLQ+++ +   + A  +C++  +  P
Sbjct: 1038 LEKMPSIPEEPEQGELERLSIPD--------FLRPLQDLE-VGLAKEAMLECQVTGLPYP 1088

Query: 2407 TLKVEWFRNEKLIE--DSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            T  + WF N   I+  D  R+T+  D     +    V  +  GVY    +N LG+
Sbjct: 1089 T--ISWFHNGHRIQSSDDRRMTQYRDVH--RLVFPAVGPQHAGVYKSVIANKLGK 1139



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 37/117 (31%), Positives = 61/117 (52%), Gaps = 3/117 (2%)

Query: 49   TTQVESSGDRQPITAGRPGEPS-PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR 107
            T ++ ++ D    +A     PS  P+F ++ ++    +G  A+F+ K+ G P PVV+WT 
Sbjct: 911  TCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTH 970

Query: 108  KKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
               P+ E    ++R  +  G  SL I  +G  DEG Y  +A N +G+A CS  +  E
Sbjct: 971  FGCPMEESE--NLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1025



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 40/135 (29%), Positives = 57/135 (42%), Gaps = 5/135 (3%)

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            +   + L I  V+  D G +TC ARN+ G       L + E     AP+F      + V 
Sbjct: 1314 DDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAE-----APRFESIMEDVEVG 1368

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             GE         G P P I W KD V +  +  +    +    +L +    A D   Y C
Sbjct: 1369 AGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTC 1428

Query: 564  TAQNVAGSTATRARL 578
            TAQN+AG  + +A L
Sbjct: 1429 TAQNLAGEVSCKAEL 1443



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 62/210 (29%), Positives = 92/210 (43%), Gaps = 16/210 (7%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            +++EG++A F+ ++       +T  W   G  +  +  ++   D G  +L IA V +ED 
Sbjct: 945  EVLEGRAARFDCKISGTPPPVVT--WTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDE 1002

Query: 1114 GVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEIS 1173
            G+Y V A N  G+A  SA + VE   +   +S      EK   I E    EP  Q E   
Sbjct: 1003 GLYAVSAVNTHGQAHCSAQLYVEEPRT--AASGPSSKLEKMPSIPE----EP-EQGELER 1055

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS--RFKTYYD 1231
             S P F++PL +   V   K   LEC++  +  PT  + WFHNG  +      R   Y D
Sbjct: 1056 LSIPDFLRPLQD-LEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQSSDDRRMTQYRD 1112

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSA 1261
               +    +    A  G Y     N LG A
Sbjct: 1113 VHRLVFPAVGPQHA--GVYKSVIANKLGKA 1140



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 14/227 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F   L+ V  +EG    F+ +I   G P   + W   G  +E S         G  SL
Sbjct: 935  PLFTRLLEDVEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSL 992

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQHPETLQYIQQLEDYSK 755
             +  +  +D G Y   AV+  G A   A L+V  PR      S   E +  I        
Sbjct: 993  HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIP------- 1045

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
             +  E  E +    P F+RPLQDL E+   + A  E Q+T +  PT  + W+ +G  I +
Sbjct: 1046 -EEPEQGELERLSIPDFLRPLQDL-EVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQS 1101

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            S             L    +  + AG Y     NKLG+A   A + V
Sbjct: 1102 SDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 1148



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 62/229 (27%), Positives = 94/229 (41%), Gaps = 18/229 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P FT    D+ + E  +A F+C++         V W H G P+     ++   D G   L
Sbjct: 935  PLFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHSL 992

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES-IQKLE 3676
             I  V   D GLY   A N HG+A  S +L V+       EP+  +   SG  S ++K+ 
Sbjct: 993  HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE-------EPRTAA---SGPSSKLEKMP 1042

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
                + E+   E E+ + P F   ++D ++V        +C+V  +  PT  I WFHNG 
Sbjct: 1043 SIPEEPEQ--GELERLSIPDFLRPLQD-LEVGLAKEAMLECQVTGLPYPT--ISWFHNGH 1097

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               +              L    +  + AG Y     NK G A   A +
Sbjct: 1098 RIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHL 1146



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 1/96 (1%)

Query: 387  EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
            E A AP+F  + +D +V  G+  RF   V G+P P++ W+  D  +  + +H   V E  
Sbjct: 1351 ELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWY-KDEVLLTESSHVSFVYEEN 1409

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
              +L++ +    D GV TC A+N +GE + +  L V
Sbjct: 1410 ECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1445



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 58/258 (22%), Positives = 104/258 (40%), Gaps = 21/258 (8%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            ++  +E    P F + ++ N+ V  G  V   C +    +P  ++ W  +G    +  R+
Sbjct: 583  VSAGEEPLEAPVFEIPLQ-NVVVAPGADVLLKCII--TANPPPQVSWHKDGSALRSEGRL 639

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC--------------SAK 3790
                +     L +    A DAG Y   ATN+ G AT  A +T               S +
Sbjct: 640  LLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDE 699

Query: 3791 RDIVLESQLPQ-GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRF 3849
              +    + P+ G +  +   ++     +    +     PP F   +   +V E + V  
Sbjct: 700  EYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIM 759

Query: 3850 ECRVEPKEDPKLRIEWYRNGK-LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
              RV+   +PK  + W RN + + P   R+    + G   L IL     D+G Y C+AVN
Sbjct: 760  SIRVQG--EPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVN 817

Query: 3909 DFGEDFTKATISCKKLPD 3926
            ++G    +A +  +  P+
Sbjct: 818  EYGARQCEARLEVRAHPE 835



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 65/268 (24%), Positives = 109/268 (40%), Gaps = 23/268 (8%)

Query: 3396 KLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVE 3455
            +L++ +DS V     S  EE  +APVF +PL N+  +  G +   +  +T    P  +V 
Sbjct: 574  ELESSDDSYV-----SAGEEPLEAPVFEIPLQNVV-VAPGADVLLKCIITANPPP--QVS 625

Query: 3456 WYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ-G 3514
            W+ +G +L++  R     +     L +      D+G Y+  A N  G+A   AS+ V+ G
Sbjct: 626  WHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPG 685

Query: 3515 KRNIILESQLPKGME--GTIDKIAALEGYSGTVDTLTP-------EAESGN--PPEFTTT 3563
                   S +    E     ++            T+ P        +++G+  PP F  +
Sbjct: 686  GSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVS 745

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS-RVKTINDFGFVILEIGGV 3622
              D  + E        R+    +    V W  N +P+     R     + G   L I   
Sbjct: 746  LMDQSVREGQDVIMSIRV--QGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAA 803

Query: 3623 YQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             + DAG YTCKA N +G      +L+V+
Sbjct: 804  ERGDAGFYTCKAVNEYGARQCEARLEVR 831



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 57/216 (26%), Positives = 92/216 (42%), Gaps = 13/216 (6%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P+FT+ L++++ + EG+ A FDC++   G P   V W      +E+S  +    D G  S
Sbjct: 935  PLFTRLLEDVE-VLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 991

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQ-PH 2494
            + I+HV  EDEG+Y   A N  G+               +  T       K++K+   P 
Sbjct: 992  LHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE-----EPRTAASGPSSKLEKMPSIPE 1046

Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
            E    E +R    P F + L    E+   + A  E +V  +  P++   W+ NG  ++  
Sbjct: 1047 EPEQGELER-LSIPDFLRPLQ-DLEVGLAKEAMLECQVTGLPYPTI--SWFHNGHRIQSS 1102

Query: 2555 SRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
               R T       L   +V    AG+Y     N+ G
Sbjct: 1103 DDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLG 1138



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 66/254 (25%), Positives = 101/254 (39%), Gaps = 24/254 (9%)

Query: 2222 QLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHN 2281
            +LE+   S     EEP +  P F   L+    V  G     +C +    +P  ++ ++ +
Sbjct: 574  ELESSDDSYVSAGEEP-LEAPVFEIPLQNVV-VAPGADVLLKCIITA--NPPPQVSWHKD 629

Query: 2282 GKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGS-- 2339
            G AL+S  R  +  +    +L ++     DAG Y   A N LG  T A S+TV   GS  
Sbjct: 630  GSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTS 689

Query: 2340 -----IISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQR---------PVFTQPLQNI 2385
                 I S+ +     E+  E     P      P P   +R         P F   L + 
Sbjct: 690  PFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMD- 748

Query: 2386 DNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-DSSRITKTHDFGYVSMTISHVRDE 2444
             +++EGQ      R+   G+P   V W RN + +  D  R  +  + G   + I      
Sbjct: 749  QSVREGQDVIMSIRV--QGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERG 806

Query: 2445 DEGVYMCRASNLLG 2458
            D G Y C+A N  G
Sbjct: 807  DAGFYTCKAVNEYG 820



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 68/268 (25%), Positives = 110/268 (41%), Gaps = 25/268 (9%)

Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367
            ++AP F   L N+    G +V L+C +    +   +V W  +G  +++  R     E + 
Sbjct: 590  LEAPVFEIPLQNVVVAPGADVLLKCII--TANPPPQVSWHKDGSALRSEGRLLLRAEGER 647

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
              L L      D+G Y   ATN+LG+A  + +L V         S   +  E  +YL   
Sbjct: 648  HTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDE--EYLSPP 705

Query: 1428 SRYKKT-DIIDESVTIKPRFVTRPKSI----------------ENVIEGQHVHFECKLEP 1470
              + +  +    + T+KP      +S                 ++V EGQ V    +++ 
Sbjct: 706  EEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQ- 764

Query: 1471 VTDSNLKVEWFKNGQPVTIG-HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
              +    V W +N QPV     RF    + G   L I+     D+G YTC+AVN  G  +
Sbjct: 765  -GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQ 823

Query: 1530 VSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
               RL  R+  +  RS    A L+ + V
Sbjct: 824  CEARLEVRAHPE-SRSLAVLAPLQDVDV 850



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 64/245 (26%), Positives = 99/245 (40%), Gaps = 22/245 (8%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            PVF  PL N   V+ G ++ L+C +    +P  +V W  +G ++    R     +     
Sbjct: 593  PVFEIPLQNVV-VAPGADVLLKCIIT--ANPPPQVSWHKDGSALRSEGRLLLRAEGERHT 649

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE-------RSDIVTDTQNEQAIEQIQ 1289
            L +  A +AD G Y   A N LG A  +A + V          S I +D +     E+  
Sbjct: 650  LLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFP 709

Query: 1290 LLEDAARRTKQVR---------EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQ 1340
               +   RT  ++          D      P F  +L +    EG +V +  R+Q  G+ 
Sbjct: 710  EPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQ--GEP 767

Query: 1341 TMRVEWFCNGKPIKTG-HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCA 1399
               V W  N +P++    RF    E     L +L+    D+G YTC+A N+ G       
Sbjct: 768  KPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEAR 827

Query: 1400 LRVIA 1404
            L V A
Sbjct: 828  LEVRA 832



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 63/254 (24%), Positives = 102/254 (40%), Gaps = 18/254 (7%)

Query: 3396 KLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVE 3455
            KL T +D +      +V      AP+FT  L ++E L EG  A F+ +++ T  P   V 
Sbjct: 913  KLSTAKDELTCSARLTVRPSL--APLFTRLLEDVEVL-EGRAARFDCKISGTPPP--VVT 967

Query: 3456 WYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            W   G  ++     R   D G   L I+    ED G Y   A N +G+A  +A + V+  
Sbjct: 968  WTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEP 1027

Query: 3516 RNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSA 3575
            R          G    ++K+ ++       +    E E  + P+F     DL +     A
Sbjct: 1028 RT------AASGPSSKLEKMPSI-----PEEPEQGELERLSIPDFLRPLQDLEVGLAKEA 1076

Query: 3576 HFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKAT 3635
              EC++  +   +  + WFHNG  + +    +         L    V  + AG+Y     
Sbjct: 1077 MLECQVTGLPYPT--ISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIA 1134

Query: 3636 NRHGEATVSCKLQV 3649
            N+ G+A     L V
Sbjct: 1135 NKLGKAACYAHLYV 1148



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P FE I ++     G  A+F   + G P P + W + +  L E +  S  Y E   + SL
Sbjct: 1356 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEE--NECSL 1413

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAIC 157
            ++   G  D G YTCTA+N  GE  C
Sbjct: 1414 VVLSTGAQDGGVYTCTAQNLAGEVSC 1439



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 60/246 (24%), Positives = 100/246 (40%), Gaps = 21/246 (8%)

Query: 3641 ATVSCKLQVKGRQGIILEPQLPSHFKSG--TESIQKLEETLHKREEITIEDEKPNPPRFT 3698
            A + CK+   GR+  +L   +     SG  T  +   ++ L     +T+       P FT
Sbjct: 882  ALLKCKMHFDGRKCKLLLTSVHED-DSGVYTCKLSTAKDELTCSARLTVRPSLA--PLFT 938

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDID 3758
              ++D ++V EG    FDC++   G P   + W H G P      +    D G  +L I 
Sbjct: 939  RLLED-VEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIA 995

Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISD 3818
            ++ + D G Y   A N  G A  +A++     R            SG   K  +   I +
Sbjct: 996  HVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPR---------TAASGPSSKLEKMPSIPE 1046

Query: 3819 APKEEPIVS-TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG-KLLPSGH 3876
             P++  +   + P F+  ++   V  ++    EC+V     P   I W+ NG ++  S  
Sbjct: 1047 EPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYP--TISWFHNGHRIQSSDD 1104

Query: 3877 RYRTVY 3882
            R  T Y
Sbjct: 1105 RRMTQY 1110



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 61/225 (27%), Positives = 98/225 (43%), Gaps = 16/225 (7%)

Query: 913  TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIK 972
            T + + + + EG  A F+ ++   G     V W   G P+E S  +    + G  +L I 
Sbjct: 938  TRLLEDVEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIA 995

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKR 1032
             V   D G Y   A N  GQA  SA L +  ++   A S     LEK+  + +     + 
Sbjct: 996  HVGSEDEGLYAVSAVNTHGQAHCSAQLYV--EEPRTAASGPSSKLEKMPSIPE-----EP 1048

Query: 1033 TEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN-- 1090
             + E++    P FL PL+   ++   + A  E +V        T+ W+ NG +I S++  
Sbjct: 1049 EQGELERLSIPDFLRPLQDL-EVGLAKEAMLECQVTGLP--YPTISWFHNGHRIQSSDDR 1105

Query: 1091 RIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            R+  Y D     L   +V  + +GVY  V  N  G+A   A + V
Sbjct: 1106 RMTQYRDVH--RLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 1148



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 2/113 (1%)

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
            PL++ +VA G  +   C I   P P V W+K    ++      +    + +TL + EA  
Sbjct: 598  PLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARA 657

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             D G Y   A N  G+ T AA L V +P  + + P  +P+     Y   P +F
Sbjct: 658  ADAGSYMATATNELGQATCAASLTV-RPGGSTS-PFSSPITSDEEYLSPPEEF 708



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 33/97 (34%), Positives = 45/97 (46%)

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
            G   +  P F +  QNV V  G  V L   +T   P  V W K+G  ++ + R  +  E 
Sbjct: 586  GEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEG 645

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
              +TLL+ EA   D+G Y   A N  G+A C A   V
Sbjct: 646  ERHTLLLREARAADAGSYMATATNELGQATCAASLTV 682



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 62/237 (26%), Positives = 102/237 (43%), Gaps = 22/237 (9%)

Query: 767  SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG 826
            S  P F R L+D+ E+ EGR A F+ +++    P   V W   G P+  S  +    + G
Sbjct: 932  SLAPLFTRLLEDV-EVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGG 988

Query: 827  YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXX 886
              SL+I H+ +ED G Y V AVN  G+A  +A + V    T  +    P  +  +EK   
Sbjct: 989  LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASG---PSSK--LEKMPS 1043

Query: 887  XXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWL 946
                             E    P+F  P++D + +     A  E ++  +   T  + W 
Sbjct: 1044 IPEEPEQGEL-------ERLSIPDFLRPLQD-LEVGLAKEAMLECQVTGLPYPT--ISWF 1093

Query: 947  KDGRPVEASS--RITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +G  +++S   R+T + +     L   +V    AG Y     N +G+A   A+L +
Sbjct: 1094 HNGHRIQSSDDRRMTQYRDVH--RLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 1148



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 57/231 (24%), Positives = 88/231 (38%), Gaps = 18/231 (7%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            +F   L ++   EG    F+C +  +  P   + W     P+      +   D    SL 
Sbjct: 936  LFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHSLH 993

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQ-AEEA 2893
            I H   ED G+Y   A N+ G A  S  L     +        P  K  LE +    EE 
Sbjct: 994  IAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTA---ASGPSSK--LEKMPSIPEEP 1048

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
               +  R S+PD   P  +  + +A E  ++E QV  L         P   I W+ NG  
Sbjct: 1049 EQGELERLSIPDFLRPLQDLEVGLAKE-AMLECQVTGL---------PYPTISWFHNGHR 1098

Query: 2954 LEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCT 3004
            ++     ++T       L    V  + +G+Y     NK G+A   + +Y T
Sbjct: 1099 IQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVT 1149



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 54/225 (24%), Positives = 91/225 (40%), Gaps = 15/225 (6%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            +++EG+    + ++     P   + W   G  +E+    +L  D G  +L +  V   D 
Sbjct: 945  EVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDE 1002

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD 3041
            G+Y   A N  G+A  S+ +Y         RT     +  LEK+     S+ +EP +Q +
Sbjct: 1003 GLYAVSAVNTHGQAHCSAQLYVEE-----PRTAASGPSSKLEKM----PSIPEEP-EQGE 1052

Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY 3101
             +    P+F    +D+ ++   + A  E  +  TG     I WF+NG  I++S   R   
Sbjct: 1053 LERLSIPDFLRPLQDL-EVGLAKEAMLECQV--TGLPYPTISWFHNGHRIQSSDDRRMTQ 1109

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKG 3146
               +  L         +G Y     NK G+A     L   D   G
Sbjct: 1110 YRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPG 1154



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 22/211 (10%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            V W+ +G  + S  R+    +     L +   RA D+G Y   A N  G+A  +AS+TV 
Sbjct: 624  VSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVR 683

Query: 1137 TRSSIDTSSIHRGLYEKTRHIEE-SKFVEPMYQIEEISKSKPVFVQPL------SNPPP- 1188
               S  TS     +     ++    +F EP          KP   Q        S  PP 
Sbjct: 684  PGGS--TSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPT 741

Query: 1189 ---------VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR-FKTYYDFGFVALD 1238
                     V EG+++ +  R++  G+P   V W  N + V    R F    + G   L 
Sbjct: 742  FKVSLMDQSVREGQDVIMSIRVQ--GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 799

Query: 1239 IIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            I+ A   D G YT +AVN  G+    A + V
Sbjct: 800  ILAAERGDAGFYTCKAVNEYGARQCEARLEV 830



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 60/258 (23%), Positives = 102/258 (39%), Gaps = 24/258 (9%)

Query: 624 YIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS 683
           Y+  GEE      P F +PL++V    G  +  +  I    +P  ++ W K+G ++ +  
Sbjct: 582 YVSAGEEP--LEAPVFEIPLQNVVVAPGADVLLKCII--TANPPPQVSWHKDGSALRSEG 637

Query: 684 RFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR-ATIERTSQHPE 742
           R          +L +      D+G Y   A +  G A   A L V P  +T   +S    
Sbjct: 638 RLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITS 697

Query: 743 TLQYIQQLEDY---------------SKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRN 787
             +Y+   E++               S  Q++ S +  +   P F   L D   ++EG++
Sbjct: 698 DEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQS-VREGQD 756

Query: 788 AHFEAQLTPVSDPTMRVEWYKDGRPITASSR-ITSIFNFGYVSLNIMHLRAEDAGSYTVR 846
                ++    +P   V W ++ +P+    R        G   L I+     DAG YT +
Sbjct: 757 VIMSIRVQ--GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCK 814

Query: 847 AVNKLGEAISTASIRVAA 864
           AVN+ G     A + V A
Sbjct: 815 AVNEYGARQCEARLEVRA 832



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 1/96 (1%)

Query: 67  GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
           G  +PP F+    +    +G +     +++G P PVVSW R + P V  ++       + 
Sbjct: 735 GSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQP-VRPDQRRFAEEAEG 793

Query: 127 GDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           G   L I     GD G YTC A N+YG   C   ++
Sbjct: 794 GLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLE 829



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 8/123 (6%)

Query: 46  RQMTTQVESSGDRQPITAGRPGEP-SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVS 104
           R  + ++ESS D   ++AG   EP   P+FE   +N   A G +   +  +  NP P VS
Sbjct: 569 RPTSPELESSDDSY-VSAGE--EPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVS 625

Query: 105 WTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC--SVYIQ 162
           W +  + L    +  +R   +    +LL+++    D G Y  TA N+ G+A C  S+ ++
Sbjct: 626 WHKDGSALRSEGRLLLRAEGERH--TLLLREARAADAGSYMATATNELGQATCAASLTVR 683

Query: 163 PEG 165
           P G
Sbjct: 684 PGG 686



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 3/116 (2%)

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
            S+  + ++ P+F   ++D+ E+  G  A F   +     P   + WYKD   +T SS ++
Sbjct: 1347 SVTLELAEAPRFESIMEDV-EVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVS 1403

Query: 821  SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPE 876
             ++     SL ++   A+D G YT  A N  GE    A + V +  T     G+ E
Sbjct: 1404 FVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGE 1459



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 49/221 (22%), Positives = 88/221 (39%), Gaps = 12/221 (5%)

Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG 1500
            ++ P F    + +E V+EG+   F+CK+         V W   G P+      R   D G
Sbjct: 932  SLAPLFTRLLEDVE-VLEGRAARFDCKISGTPPP--VVTWTHFGCPMEESENLRLRQDGG 988

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLED 1560
              +L I  + +ED G+Y   AVN  G    S +L             ++  LE++  + +
Sbjct: 989  LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSK--LEKMPSIPE 1046

Query: 1561 RSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPL 1620
              +    + +       P     L+++E+   + A  E ++  +   T  + W+HN   +
Sbjct: 1047 EPEQGELERL-----SIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRI 1099

Query: 1621 KSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            +S      T       L   +  P+ +G Y     N LG+A
Sbjct: 1100 QSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKA 1140



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 55/231 (23%), Positives = 90/231 (38%), Gaps = 16/231 (6%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF   L N+V   G ++  +C +  + +P  ++ W  +   L S  R     +    +L 
Sbjct: 594  VFEIPLQNVVVAPGADVLLKCII--TANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLL 651

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCT-GDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
            +      D+G Y   ATN  G AT + SL    G     F +     +  L   E+  E 
Sbjct: 652  LREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEP 711

Query: 2894 RLAKGRRPSVP----------DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDL 2943
                 R P++           DT    P        +  + EGQ + +  +V+   +P  
Sbjct: 712  GETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQ--GEPKP 769

Query: 2944 KIEWYFNGK-VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
             + W  N + V     RF   ++ G   L ++     D+G YTCKA N+ G
Sbjct: 770  VVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYG 820



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 44/178 (24%), Positives = 76/178 (42%), Gaps = 12/178 (6%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F+R L ++E +EG     +C++   G     V W   G P++     R   +    +
Sbjct: 934  APLFTRLLEDVEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 991

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSR 1429
            L +  V  ED G+Y   A N  G+A   C+ ++  ++     S   S LEK+  + +   
Sbjct: 992  LHIAHVGSEDEGLYAVSAVNTHGQA--HCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPE 1049

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
              +     E ++I P F+ RP     V   +    EC++  +      + WF NG  +
Sbjct: 1050 QGEL----ERLSI-PDFL-RPLQDLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRI 1099



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 43/166 (25%), Positives = 69/166 (41%), Gaps = 9/166 (5%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I      D G  +C A N+ G    SV LE  +      PRF + ++++E +  G++A
Sbjct: 1320 LRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-----PRFESIMEDVE-VGAGETA 1373

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             F   V     PD  I WY +   +  S+ +  V +     L +  T   D G Y C A 
Sbjct: 1374 RFAVVVEGKPLPD--IMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQ 1431

Query: 3228 NKYGEDFTRATINCY-GKGGVYLESLQPDSLAKIRELESLQGAQQQ 3272
            N  GE   +A +  +  +  + +E +  D   + R L       Q+
Sbjct: 1432 NLAGEVSCKAELAVHSAQTAMEVEGVGEDEDHRGRRLSDFYDIHQE 1477



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/86 (27%), Positives = 47/86 (54%), Gaps = 3/86 (3%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            + P F   +++++ +  G+TA F   ++  G P   + W+++E L+ +SS ++  ++   
Sbjct: 1354 EAPRFESIMEDVE-VGAGETARF--AVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE 1410

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             S+ +     +D GVY C A NL GE
Sbjct: 1411 CSLVVLSTGAQDGGVYTCTAQNLAGE 1436



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 3/121 (2%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + +AP F   M+D+ V   + A F   ++  G P   + W ++ V +  S+ ++ +++  
Sbjct: 1352 LAEAPRFESIMEDVEVGAGETARFA--VVVEGKPLPDIMWYKDEVLLTESSHVSFVYEEN 1409

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-KASLQLESQHESALQKIQQLE 1825
              +L +     +D G YTC A N  GE    + L V S + ++++E   E    + ++L 
Sbjct: 1410 ECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDEDHRGRRLS 1469

Query: 1826 D 1826
            D
Sbjct: 1470 D 1470



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 3/116 (2%)

Query: 3552 AESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN- 3610
            +ES  PP F     D +L E  +A   C  +P    +  + W  + K L +   V  ++ 
Sbjct: 2449 SESDFPPVFHIKLKDQVLLEGEAATLLC--LPAACPAPHISWMKDKKSLRSEPSVIIVSC 2506

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
              G  +L I    +R AGLY C ATN  G  T SC + V    G +  P++   ++
Sbjct: 2507 KDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVTQTYQ 2562



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 53/212 (25%), Positives = 83/212 (39%), Gaps = 14/212 (6%)

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
            T K  T++  LT      V     P F T++     ++E    +F+C+++  G P   V 
Sbjct: 911  TCKLSTAKDELTCSARLTVRPSLAPLF-TRLLEDVEVLEGRAARFDCKIS--GTPPPVVT 967

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
            W   G P+          D G  +++   V  ED G Y   A N +G     A +    +
Sbjct: 968  WTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE-E 1026

Query: 4069 PGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWA 4128
            P         K    +EK+  +       PEQ  E  +   P     L D + V   + A
Sbjct: 1027 PRTAASGPSSK----LEKMPSIPEE----PEQG-ELERLSIPDFLRPLQD-LEVGLAKEA 1076

Query: 4129 RFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
               C+VTG P P + W  NG+ I +    ++T
Sbjct: 1077 MLECQVTGLPYPTISWFHNGHRIQSSDDRRMT 1108



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 267  KIAQKPRNSKLQE------GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
            ++A+ PR   + E      G  A+F V + G P P + W+K+   L  S+    +   N 
Sbjct: 1351 ELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE 1410

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
             +L V +T   D G YT  A+N  G +     LAV S
Sbjct: 1411 CSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHS 1447



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 1/90 (1%)

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT- 541
            +  E    P F  +     + EGE   L       P P I+W KD   +   P + I + 
Sbjct: 2447 VRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSC 2506

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              G   L IPRA    A  Y+C+A NV GS
Sbjct: 2507 KDGRQLLSIPRAGKRHAGLYECSATNVLGS 2536



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 60/254 (23%), Positives = 91/254 (35%), Gaps = 25/254 (9%)

Query: 2355 ELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
            ELES++        EP+  + PVF  PLQN+  +  G      C  I   +P  +V W +
Sbjct: 574  ELESSDDSYVSAGEEPL--EAPVFEIPLQNVV-VAPGADVLLKC--IITANPPPQVSWHK 628

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXX----XXX 2470
            +   +    R+    +    ++ +   R  D G YM  A+N LG+               
Sbjct: 629  DGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGST 688

Query: 2471 XXXIQLETQHPEGMKKIQKLEQPHERRSEEP-------------DREFEKPIFTQVLTGP 2517
                   T   E +   ++  +P E     P             D   + P   +V    
Sbjct: 689  SPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMD 748

Query: 2518 SELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS-RFRTTHDFGFVTLDINSVVAN 2576
              + EGQ      RV   G+P     W  N   ++    RF    + G   L I +    
Sbjct: 749  QSVREGQDVIMSIRV--QGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERG 806

Query: 2577 DAGLYMCKAINRAG 2590
            DAG Y CKA+N  G
Sbjct: 807  DAGFYTCKAVNEYG 820



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 24/86 (27%), Positives = 39/86 (45%)

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
            PL+++VV  G     K  IT+   P + W ++G+ +       +  EG    LL+     
Sbjct: 598  PLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARA 657

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
             D G++   AT   GQ   +A L V+
Sbjct: 658  ADAGSYMATATNELGQATCAASLTVR 683



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096
            +++ + PRF   ++   ++  G++A F   VE +      + WY +   +T ++ +   +
Sbjct: 1350 LELAEAPRFESIMEDV-EVGAGETARFAVVVEGKP--LPDIMWYKDEVLLTESSHVSFVY 1406

Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
            +    +L + S  A+D GVYT  A+N AGE    A + V +
Sbjct: 1407 EENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHS 1447



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 56/259 (21%), Positives = 99/259 (38%), Gaps = 22/259 (8%)

Query: 3822 EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
            EEP+ +  P F   +++  V     V  +C +     P+  + W+++G  L S  R    
Sbjct: 587  EEPLEA--PVFEIPLQNVVVAPGADVLLKCIITANPPPQ--VSWHKDGSALRSEGRLLLR 642

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI------SCKKLPDIILQNQV-- 3933
             +    +L +    A D+G Y+  A N+ G+    A++      S       I  ++   
Sbjct: 643  AEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYL 702

Query: 3934 --PRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETT 3991
              P              T+K   S+   + D       K PP F   +  Q S+ E +  
Sbjct: 703  SPPEEFPEPGETWPRTPTMKPSPSQNRRSSD----TGSKAPPTFKVSLMDQ-SVREGQDV 757

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLL-HKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRA 4050
                ++   G+P   V W  N +P+   + RF    + G   +        D+G Y C+A
Sbjct: 758  IMSIRVQ--GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKA 815

Query: 4051 TNLYGMDETKAVIKTTGKP 4069
             N YG  + +A ++    P
Sbjct: 816  VNEYGARQCEARLEVRAHP 834



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 51/231 (22%), Positives = 87/231 (37%), Gaps = 20/231 (8%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP+FT  L+  + L EG+    + ++     P   + W   G  +     L+   D GL 
Sbjct: 934  APLFTRLLEDVEVL-EGRAARFDCKISGTPPP--VVTWTHFGCPMEESENLRLRQDGGLH 990

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXX 2760
            +L I  + ++D G+Y   A N  G+A  +A + +E+       S     L+++ ++    
Sbjct: 991  SLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPR--TAASGPSSKLEKMPSIPEEP 1048

Query: 2761 XXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSG- 2819
                           F+  L ++          EC V     PT  I WF N   + S  
Sbjct: 1049 EQGELERLSIPD---FLRPLQDLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQSSD 1103

Query: 2820 ----TRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
                T+Y+  H   + ++   H     +G+Y     N  G A     L  T
Sbjct: 1104 DRRMTQYRDVHRLVFPAVGPQH-----AGVYKSVIANKLGKAACYAHLYVT 1149



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+F + ++   V   E  RF   VE K  P   I WY++  LL        VY+    SL
Sbjct: 1356 PRFESIMEDVEVGAGETARFAVVVEGKPLPD--IMWYKDEVLLTESSHVSFVYEENECSL 1413

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
             +L   A+D G Y C A N  GE   KA ++
Sbjct: 1414 VVLSTGAQDGGVYTCTAQNLAGEVSCKAELA 1444



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYVSLDI 2835
            ++ L ++    G+   FEC V    D  ++++W    + L P+  + K   D     L +
Sbjct: 842  LAPLQDVDVGAGEMALFECLVAGPTD--VEVDWLCRGRLLQPALLKCKMHFDGRKCKLLL 899

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            T  +E+DSG+YTCK + +K   T S  L
Sbjct: 900  TSVHEDDSGVYTCKLSTAKDELTCSARL 927



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/92 (31%), Positives = 40/92 (43%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+F   ++ V    G    F   +E  G P   I W K+   +  SS  + ++     SL
Sbjct: 1356 PRFESIMEDVEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVSFVYEENECSL 1413

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +LS   QD G YTC A +  G    KA L V
Sbjct: 1414 VVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1445



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 5/106 (4%)

Query: 2631 EMFVDTGVQ--QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
            + +V  G +  +AP+F   L++   +  G  V L+  +     P  ++ W K+G  L + 
Sbjct: 580  DSYVSAGEEPLEAPVFEIPLQNV-VVAPGADVLLKCIITANPPP--QVSWHKDGSALRSE 636

Query: 2689 ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             RL    +    TL +   R  D+G Y   ATN LG+A   AS+ +
Sbjct: 637  GRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTV 682



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 2635 DTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR-LKS 2693
            DTG +  P F   L     + EGQ V +  +V+   +P   + W +N   +    R    
Sbjct: 733  DTGSKAPPTFKVSLMD-QSVREGQDVIMSIRVQG--EPKPVVSWLRNRQPVRPDQRRFAE 789

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
              + GL  L I +    D+G YTCKA N  G     A +++
Sbjct: 790  EAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 830



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 56/231 (24%), Positives = 88/231 (38%), Gaps = 26/231 (11%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            S  P F   ++   V E    RF+C++     P   + W   G  +      R   D G 
Sbjct: 932  SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGL 989

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQM 3946
             SL I +V +ED G Y   AVN  G+    A +  ++          PR      A +  
Sbjct: 990  HSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEE----------PR-----TAASGP 1034

Query: 3947 EATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMK 4006
             + ++K  S     E +  ++++   P F+  +Q     +  E    ECQ+   G P   
Sbjct: 1035 SSKLEKMPS--IPEEPEQGELERLSIPDFLRPLQDLEVGLAKE-AMLECQV--TGLPYPT 1089

Query: 4007 VEWFFNGKPLLHKN--RFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            + WF NG  +   +  R T   D   +   F  V P+ +G Y     N  G
Sbjct: 1090 ISWFHNGHRIQSSDDRRMTQYRDVHRLV--FPAVGPQHAGVYKSVIANKLG 1138



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 3/98 (3%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN 963
            E  + P F++ ++D + +  G  A F   +E  G     + W KD   +  SS ++  + 
Sbjct: 1351 ELAEAPRFESIMED-VEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVSFVYE 1407

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                +L + S    D G YTC A N  G+ +  A L +
Sbjct: 1408 ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1445



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 3/95 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP F + ++  + +  G+       VE +  P+  I W+K+ V LT  + +   ++   
Sbjct: 1354 EAPRFESIMEDVE-VGAGETARFAVVVEGKPLPD--IMWYKDEVLLTESSHVSFVYEENE 1410

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +L + S    D G+YTC A NL GE    A + +
Sbjct: 1411 CSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1445



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 1/94 (1%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTL 4680
            PP     LKD+++ EG+A    C     P P + W K  K ++      +    D    L
Sbjct: 2454 PPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLL 2513

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
             I  A     G Y+C A N  G +T +  + V +
Sbjct: 2514 SIPRAGKRHAGLYECSATNVLGSITSSCTVAVAR 2547



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 2370 PVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH 2429
            P +R   V   PLQ++D +  G+ A F+C  +  G   ++V+W    +L++ +    K H
Sbjct: 834  PESRSLAVLA-PLQDVD-VGAGEMALFEC--LVAGPTDVEVDWLCRGRLLQPALLKCKMH 889

Query: 2430 -DFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             D     + ++ V ++D GVY C+ S    E
Sbjct: 890  FDGRKCKLLLTSVHEDDSGVYTCKLSTAKDE 920



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 21/56 (37%), Positives = 28/56 (50%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH 4166
            P+F  L + V V EG  ARF C+++G P P V W   G  +      +L  DG  H
Sbjct: 935  PLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLH 990



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 3/83 (3%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFGFVA 1636
            P    SL +  ++EGQ      R+    +    V W  N +P++   R F E    G   
Sbjct: 740  PTFKVSLMDQSVREGQDVIMSIRV--QGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCR 797

Query: 1637 LDIMSCLPEDSGTYTCRAINALG 1659
            L I++    D+G YTC+A+N  G
Sbjct: 798  LRILAAERGDAGFYTCKAVNEYG 820



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 21/105 (20%), Positives = 44/105 (41%)

Query: 4396 TQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP 4455
            + +  V    +P + P+F   +Q   V        +      P P + W+++   +++  
Sbjct: 578  SDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEG 637

Query: 4456 DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
               +     +  L++R+    D+  + A A N  G A C+A+L V
Sbjct: 638  RLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTV 682



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 45/161 (27%), Positives = 65/161 (40%), Gaps = 18/161 (11%)

Query: 4002 DPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
            +P  +V W  +G  L  + R     +     +        D+G Y+  ATN  G     A
Sbjct: 619  NPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAA 678

Query: 4062 VIKTTGKPG---IVYDSQLP---KHMKSIEKIREMEASWQVTPEQVVEESKAR------- 4108
             +  T +PG     + S +    +++   E+  E   +W  TP      S+ R       
Sbjct: 679  SL--TVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGS 736

Query: 4109 -CPPVF-VSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
              PP F VSL D  +V EG+      RV G PKP V WL N
Sbjct: 737  KAPPTFKVSLMDQ-SVREGQDVIMSIRVQGEPKPVVSWLRN 776



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/116 (23%), Positives = 45/116 (38%)

Query: 376  QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            Q E   +   SE    P F    +D+ + EG+     C     P P ++W  + + +R +
Sbjct: 2439 QEELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSE 2498

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
             +  I+  + G   L I       +G+  C A N  G     C + V      +AP
Sbjct: 2499 PSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAP 2554



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 5/92 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F ++ +D V++  G+ A +  +++  G     I W+ +   +  S  +  VY      
Sbjct: 1356 PRFESIMED-VEVGAGETARF--AVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECS 1412

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
            L +L T   D G Y+C A N  G  E+S K E
Sbjct: 1413 LVVLSTGAQDGGVYTCTAQNLAG--EVSCKAE 1442



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 2/118 (1%)

Query: 366 QRSQYITDTQQRETEERIEISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
           +R++  +   +   +  +   E+ L AP F    Q+  V  G      C +T  P P+V+
Sbjct: 566 RRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVS 625

Query: 425 WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           W  +   +R +    +L  E   H L++     +D+G     A N+ G+      L V
Sbjct: 626 WHKDGSALRSE-GRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTV 682



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 1/87 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDFQMIHEGNNAVLLIGNTYE 4785
            L D  V EGQ      ++  + KP + WLR    + P+   F    EG    L I     
Sbjct: 746  LMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAER 805

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
             D G +TC+A    G  +  A+L V++
Sbjct: 806  GDAGFYTCKAVNEYGARQCEARLEVRA 832



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 14/130 (10%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLE--PVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            PRF +  + +E V  G+   F   +E  P+ D    + W+K+   +T       +++   
Sbjct: 1356 PRFESIMEDVE-VGAGETARFAVVVEGKPLPD----IMWYKDEVLLTESSHVSFVYEENE 1410

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDR 1561
             +L ++   A+D G+YTC A NL G  EVSC+         V S Q    +E +   ED 
Sbjct: 1411 CSLVVLSTGAQDGGVYTCTAQNLAG--EVSCKAEL-----AVHSAQTAMEVEGVGEDEDH 1463

Query: 1562 SKYHRTDMVD 1571
                 +D  D
Sbjct: 1464 RGRRLSDFYD 1473



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 4/89 (4%)

Query: 914  PIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVE-ASSRITTFFNFGYVALTIK 972
            P++D + +  G  A FE  +   G + + V+WL  GR ++ A  +    F+     L + 
Sbjct: 844  PLQD-VDVGAGEMALFECLVA--GPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLT 900

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            SV   D+G YTC+   A  + T SA LT+
Sbjct: 901  SVHEDDSGVYTCKLSTAKDELTCSARLTV 929



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 2/99 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            +AP   + +++VE+  G+ A F   ++        + WY +   L   S  +        
Sbjct: 1354 EAPRFESIMEDVEVGAGETARFA--VVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENEC 1411

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674
            +L ++S   +D G YTC A N  GE        VHS ++
Sbjct: 1412 SLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQT 1450



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 3/106 (2%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + + +APRF + +    ++  G++A +   +E  P P+  + WY +  +L        
Sbjct: 1348 VTLELAEAPRFESIMED-VEVGAGETARFAVVVEGKPLPD--IMWYKDEVLLTESSHVSF 1404

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
              +    +L +L+   +D G YTC A N  G+      L V S ++
Sbjct: 1405 VYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQT 1450



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + + +AP+F   + ++E   G        ++  G     + W+ +   +         YE
Sbjct: 1350 LELAEAPRFESIMEDVEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVSFVYE 1407

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +  +L +LS   +D GVYTC A N  GE      L V
Sbjct: 1408 ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1445



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 3/112 (2%)

Query: 2090 ELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
            ELE  +       E+P + PVF   L ++  +  G     +C +    +P   + W  +G
Sbjct: 574  ELESSDDSYVSAGEEPLEAPVFEIPLQNVV-VAPGADVLLKCIITA--NPPPQVSWHKDG 630

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              +R+  R     +     L +    A D+G+YM  ATN+LG+A    +L V
Sbjct: 631  SALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTV 682



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA-RLKSTFDFGLVTLSINSLRNDDSGIY 2715
            G+    E  V   TD  ++++W   G  L     + K  FD     L + S+  DDSG+Y
Sbjct: 853  GEMALFECLVAGPTD--VEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVY 910

Query: 2716 TCKATNLLGEAVSTASIKI 2734
            TCK +    E   +A + +
Sbjct: 911  TCKLSTAKDELTCSARLTV 929



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 8/117 (6%)

Query: 2621 LKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDK-LVEGQHVYLEAQVEPRTDPNLKIEWF 2679
            L  +   ++   +V +     P+F  H+K  D+ L+EG+   L     P   P   I W 
Sbjct: 2434 LSASVQEELGHQYVRSESDFPPVF--HIKLKDQVLLEGEAATLLCL--PAACPAPHISWM 2489

Query: 2680 KNGVTLTT--GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            K+  +L +     + S  D G   LSI       +G+Y C ATN+LG   S+ ++ +
Sbjct: 2490 KDKKSLRSEPSVIIVSCKD-GRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 2545



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746
            +  E   PP F +++KD + + EG      C   P   P   I W  + +   +   V  
Sbjct: 2447 VRSESDFPPVFHIKLKDQV-LLEGEAATLLCL--PAACPAPHISWMKDKKSLRSEPSVII 2503

Query: 3747 LN-DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            ++   G   L I     R AG Y C ATN  GS T++  +
Sbjct: 2504 VSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTV 2543



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 3/88 (3%)

Query: 1983 PIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH-RFKTTYDFGYVALDILY 2041
            P+++ +V  G     E  +    D  + V+W C GR +Q    + K  +D     L +  
Sbjct: 844  PLQDVDVGAGEMALFECLVAGPTD--VEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTS 901

Query: 2042 AYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             + +D+G Y CK + A  E   ++ + V
Sbjct: 902  VHEDDSGVYTCKLSTAKDELTCSARLTV 929



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 3/106 (2%)

Query: 3680 HKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA 3739
            H  +  ++  E    PRF   I ++++V  G    F   VE  G P   I W+ +     
Sbjct: 1341 HGTQTCSVTLELAEAPRFE-SIMEDVEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLT 1397

Query: 3740 TGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
              S V  + +    +L +    A+D G YTC A N  G  +  A++
Sbjct: 1398 ESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAEL 1443



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/110 (21%), Positives = 46/110 (41%), Gaps = 3/110 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            + E P+F   +++ EV  G        +     P   + WY +   + +       Y+  
Sbjct: 1352 LAEAPRFESIMEDVEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVSFVYEEN 1409

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDE 2082
              +L +L   A+D G Y C A N  GE    + + V  A++ + ++ + E
Sbjct: 1410 ECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGE 1459



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 3/86 (3%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS-RVKTINDFGFVILEIGGVYQ 3624
            D+ +     A FEC +    D  + V+W   G+ L     + K   D     L +  V++
Sbjct: 847  DVDVGAGEMALFECLVAGPTD--VEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHE 904

Query: 3625 RDAGLYTCKATNRHGEATVSCKLQVK 3650
             D+G+YTCK +    E T S +L V+
Sbjct: 905  DDSGVYTCKLSTAKDELTCSARLTVR 930



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/52 (34%), Positives = 24/52 (46%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P F S+ + V V  GE ARF   V G P P +MW  +   +   S     Y+
Sbjct: 1356 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYE 1407



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI--EASNRLTTMHDFGYV 1768
            PVF + +KD  + E +AA      +P   P   + W+++   +  E S  + +  D G  
Sbjct: 2455 PVFHIKLKDQVLLEGEAATLLC--LPAACPAPHISWMKDKKSLRSEPSVIIVSCKD-GRQ 2511

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             L++       +G Y C A N LG   +S T+ V
Sbjct: 2512 LLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 2545



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 10/106 (9%)

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            T +   E    P F +   D+ +    +A F   ++        + W+ +   L   S V
Sbjct: 1345 TCSVTLELAEAPRFESIMEDVEVGAGETARFA--VVVEGKPLPDIMWYKDEVLLTESSHV 1402

Query: 3607 KTI---NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              +   N+   V+L  G    +D G+YTC A N  GE  VSCK ++
Sbjct: 1403 SFVYEENECSLVVLSTGA---QDGGVYTCTAQNLAGE--VSCKAEL 1443



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F S + ++    G+   F   VE    P   I W+ +   L   +     ++ +  SL +
Sbjct: 1358 FESIMEDVEVGAGETARFAVVVEGK--PLPDIMWYKDEVLLTESSHVSFVYEENECSLVV 1415

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
              T  +D G+YTC A N  G  +    L
Sbjct: 1416 LSTGAQDGGVYTCTAQNLAGEVSCKAEL 1443



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 2926 GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
            G+       VE K  PD  I WY +  +L + S      +    +L ++    +D G+YT
Sbjct: 1370 GETARFAVVVEGKPLPD--IMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYT 1427

Query: 2986 CKAYNKRGEAFTSSTVYCTSKDNLIE 3011
            C A N  GE    + +   S    +E
Sbjct: 1428 CTAQNLAGEVSCKAELAVHSAQTAME 1453



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH-DFGYV 2167
            PVF   L   + L EG+ A   C       PH  I W  + + +R+           G  
Sbjct: 2455 PVFHIKLKD-QVLLEGEAATLLCLPAACPAPH--ISWMKDKKSLRSEPSVIIVSCKDGRQ 2511

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
             L I       +G Y C ATN LG   ++CT+ VA
Sbjct: 2512 LLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVA 2546


>EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform A
            protein.
          Length = 1896

 Score =  120 bits (290), Expect = 1e-25
 Identities = 117/429 (27%), Positives = 176/429 (41%), Gaps = 39/429 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP F +  +P RV    +A  +    GEP P++ W +    +  S          +  L+
Sbjct: 11   PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 70

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVV-------------EEKRRQGRGGIVPPSF 4516
            +      D+ V+   A N  G A  +A + V             E        G   P F
Sbjct: 71   LTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVF 130

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP--DIRNKILE----EDG--- 4567
                ++  V  G  V L  +  G     +YW K+G  +    D  +  L+    EDG   
Sbjct: 131  LTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGA 190

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            +  L IL A   DSG Y C A N+ G A+  A   V  P       P      AP  ++E
Sbjct: 191  SLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPD----EAPAPVVE 246

Query: 4628 PLK--DKI--VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-YTLRI 4682
            PLK   K   V EG+  +F C ++GKP P ++W+   + + P +   M R  D  + L++
Sbjct: 247  PLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKV 306

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                 +D G Y C A NSAG+   A +L V +P     L    PL+D+   E   A  + 
Sbjct: 307  LYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP----RLRFTRPLQDVEGREHGIAVLEC 362

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            ++ +   PT  W RE   +     ++ I EG    L+I     +D G + C      G+V
Sbjct: 363  KVPNSRIPT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE---MRGRV 418

Query: 4803 ETSAKLVVK 4811
             T A + VK
Sbjct: 419  RTVANVTVK 427



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 90/338 (26%), Positives = 133/338 (39%), Gaps = 34/338 (10%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           SPP   + PR  ++  GA+A+ +  + G P P V W K GQ+L  S +           L
Sbjct: 10  SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +     +D+G Y   A N  G    +  + V  P  S           D + +  E  +
Sbjct: 70  LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAS-----------DPELQPAERPL 118

Query: 384 EISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD--DYNHKI 440
                   AP F+   + + V  G      CR  G P P + W  +   + +  D +H  
Sbjct: 119 PSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFA 178

Query: 441 LVN---ESG---NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV--------IEKE 486
           L     E G   + AL I    L DSGV  C ARN  G       L V         + +
Sbjct: 179 LQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPD 238

Query: 487 QVVAPKFVERFS----TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542
           +  AP  VE       T  V EG+        +G P P I W  +G P++P+    ++ D
Sbjct: 239 EAPAP-VVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRD 297

Query: 543 -GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             G   L +   +A D   Y C A+N AG T +  +L+
Sbjct: 298 RDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLH 335



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 75/307 (24%), Positives = 112/307 (36%), Gaps = 31/307 (10%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL--INSNKHEIITTHN---- 319
           P     PR+  +  GA+     +  G P P + W K+G  L  +  + H  +        
Sbjct: 128 PVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDG 187

Query: 320 ---HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
                 LR+   +  DSG Y   A N +G       L V  P ES   D       D   
Sbjct: 188 PGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP------DEAP 241

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
               E ++ + K              V EGK  +F C V G+P PE+ W    R +  D 
Sbjct: 242 APVVEPLKCAPKTFW-----------VNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDR 290

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER 496
              +  +  G   L +      D G+  C ARN +G+T    +L+V E       +F   
Sbjct: 291 RRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRL----RFTRP 346

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
              +  RE    VL  +   +  P   W ++   ++P  +     +G    L I R KA 
Sbjct: 347 LQDVEGREHGIAVLECKVPNSRIP-TAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKAD 405

Query: 557 DAAWYQC 563
           D   Y C
Sbjct: 406 DDGIYLC 412



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 99/399 (24%), Positives = 168/399 (42%), Gaps = 50/399 (12%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            + ++   + E   A F++E   E +   +W R    +   P   IH+   +  L++  + 
Sbjct: 1544 RPLEDVTISEGGSATFQLELSQEGVTG-EWARGGVQLYPGPKCHIHSDGHRHRLVLNGLG 1602

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            + DS   +  A++     +C+A L+V E         VP +      ++ VT G     +
Sbjct: 1603 LADSGCVSFTADS----LRCAARLIVRE---------VPVTIVRGPHDLEVTEGDTATFE 1649

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY-PQDSGKYECVAINSAG 4593
             +++     DV W K+G  + P  R + L+  GT  LL L    P D+G Y C    + G
Sbjct: 1650 CELSQALA-DVTWEKDGNALTPSPRLR-LQALGTRRLLQLRRCGPSDAGTYSC----AVG 1703

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
             AR      V L       + +T A      ++  L+     EG    F C  V +   T
Sbjct: 1704 TARAGP---VRLTV-----RERTVA------VLSELRSVSAREGDGATFECT-VSEVETT 1748

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             +W  G + ++P    ++ +   ++ L +SE   ED G+ +      AG     A L+V 
Sbjct: 1749 GRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGEVRF----QAGPAQSLALLEVE 1804

Query: 4714 Q-PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
              P Q    P     R+  V  G+ A  +  + S+    + WLREGA +     ++M   
Sbjct: 1805 ALPLQMCRHPP----REKTVLVGRRAVLEVTV-SRSGGHVCWLREGAELCPGDKYEMRSH 1859

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G    L+I +   ED GT+ C+    AGQ  T  +L+V+
Sbjct: 1860 GPTHSLVIHDVRPEDQGTYCCQ----AGQDSTHTRLLVE 1894



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 91/370 (24%), Positives = 149/370 (40%), Gaps = 36/370 (9%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++WY++   ++ S   Q+        L +     ED+  +  V E R      + N+++ 
Sbjct: 1112 VRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEY--VCETRHEAI--TFNVILA 1167

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E   Q       PS       + V  G+ V L  +++      V W  NG+ VQ     +
Sbjct: 1168 EPPVQFLALETTPS------PLCVAPGEPVVLSCELSRAGA-PVVWSHNGRPVQEGEGLE 1220

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +  E     L I  A P  +G Y C +  + G          SL  T    +P  +   A
Sbjct: 1221 LHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAP--------SLSFTVQVAEPPVRVV-A 1271

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P      ++      G  +E    + G   P V+WYK  + +      Q+ +      LR
Sbjct: 1272 PEAAQTRVRS---TPGGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLR 1327

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            +  A   D G+Y C A   + R+ + +   V +P     +  LTPL    V+EG  A F+
Sbjct: 1328 VQGARSGDAGEYLCDAPQDS-RIFLVS---VEEPLLVKLVSELTPL---TVHEGDDATFR 1380

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             ++ S     + WLR GA++   P  +M   G++ +L +      D GT T R    AG 
Sbjct: 1381 CEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLR----AGS 1435

Query: 4802 VETSAKLVVK 4811
              TSA+L V+
Sbjct: 1436 TATSARLHVR 1445



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 101/459 (22%), Positives = 162/459 (35%), Gaps = 51/459 (11%)

Query: 4370 KEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQAR 4429
            +   G+      +T  E    + + Q  ER +  P      P+F    +   V    +  
Sbjct: 87   RNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVV 146

Query: 4430 FEVEFDGEPLPLIKWYRENFPIK---NSPDFQIHTFSTKS------ILIIRQVFVEDSAV 4480
                  G P P + W ++   +    +S  F +     +        L I    + DS V
Sbjct: 147  LTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGV 206

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRR-------QGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
            +   A N  G A+  A L V +          +    +V P      +   V  G+  + 
Sbjct: 207  YVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEP-LKCAPKTFWVNEGKHAKF 265

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECVAINSA 4592
               V G    ++ W   G+ + PD R  +  + DG + L +L    +D G Y C A NSA
Sbjct: 266  RCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSA 325

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
            G+     +  V  P  +                  PL+D    E       CK+    +P
Sbjct: 326  GQTLSAVQLHVKEPRLR---------------FTRPLQDVEGREHGIAVLECKVPNSRIP 370

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            T  W++ D+ + P + ++         L I     +D+G Y C      GRV   A + V
Sbjct: 371  TA-WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC---EMRGRVRTVANVTV 426

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
              P     LP     R + V EG+ A    + T +     +W R+G    E P       
Sbjct: 427  KGP-ILKRLP-----RKLDVLEGENAVLLVE-TLEAGVEGRWSRDG---EELPVICQSSS 476

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G+   L++     ED G      T + G   T+  L VK
Sbjct: 477  GHMHALVLPGVTREDAG----EVTFSLGNSRTTTLLRVK 511



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 103/376 (27%), Positives = 144/376 (38%), Gaps = 64/376 (17%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F    + +RV     A  E + + +G+P   V W + G  + AS RL+   D     L
Sbjct: 12   PCFLRFPRPVRVVSGAEA--ELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +    P D+G Y CRA N  GEA  ++ + V    +   E Q                 
Sbjct: 70   LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPA--------------- 114

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTK--LSEGQSAHYECRIEPYPDPNMRVEWYFNG---- 1884
            +R      +   AP F+T   GP    +  G      CR    P+P +   W  +G    
Sbjct: 115  ERPLPSPGSGEGAPVFLT---GPRSQWVLRGAEVVLTCRAGGLPEPTL--YWEKDGMALD 169

Query: 1885 KVLQSGH----RYRTSNDFGFA-ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-QS 1938
            +V  S H      R  +  G + AL IL     DSG Y C A N  G A +   L V Q 
Sbjct: 170  EVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQP 229

Query: 1939 KESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLE 1998
             ES   D     A                       V +P    P K   V EG   H +
Sbjct: 230  PESPPADPDEAPA----------------------PVVEPLKCAP-KTFWVNEGK--HAK 264

Query: 1999 ATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
                 +  P   +EW+  GRP+    R       D G+V L +LY  A+D G Y+C A N
Sbjct: 265  FRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARN 323

Query: 2057 AVGEAVTTSSVKVDAK 2072
            + G+  T S+V++  K
Sbjct: 324  SAGQ--TLSAVQLHVK 337



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 97/381 (25%), Positives = 143/381 (37%), Gaps = 59/381 (15%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            + G+PP F   P  + +   + A  +C  + + +    V W   G+ L    R+    D 
Sbjct: 7    DQGSPPCFLRFPRPVRVVSGAEAELKC--VVLGEPPPVVVWEKGGQQLAASERLSFPADG 64

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
                L +      DAG+Y C+A N  GEA  +  + V       LEP       +    +
Sbjct: 65   AEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV-------LEPP------ASDPEL 111

Query: 3673 QKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT------ 3726
            Q  E  L               P F    +    V  G  V   CR   + +PT      
Sbjct: 112  QPAERPLPS------PGSGEGAPVFLTGPRSQW-VLRGAEVVLTCRAGGLPEPTLYWEKD 164

Query: 3727 -MRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             M +D   +   FA             +AL I      D+G Y C A N  G A   A  
Sbjct: 165  GMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGA-- 222

Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESE 3845
                   ++   Q P+    +  +       + AP  EP+   P       K+  V E +
Sbjct: 223  -------LLQVHQPPESPPADPDE-------APAPVVEPLKCAP-------KTFWVNEGK 261

Query: 3846 GVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHR--YRTVYDMGFVSLDILYVYAEDSGEY 3902
              +F C V  K +P+  IEW+  G+ LLP   R  YR   D GFV L +LY  A+D G Y
Sbjct: 262  HAKFRCYVMGKPEPE--IEWHWEGRPLLPDRRRLMYRD-RDGGFV-LKVLYCQAKDRGLY 317

Query: 3903 ICRAVNDFGEDFTKATISCKK 3923
            +C A N  G+  +   +  K+
Sbjct: 318  VCAARNSAGQTLSAVQLHVKE 338



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 45/141 (31%), Positives = 62/141 (43%), Gaps = 9/141 (6%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            +PP  +   +   V  G   E  C ++G+P P V W KG + +  S+         E+ L
Sbjct: 10   SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN--LPALTPLRDIVVYEGQPA 4738
             ++ A P D G Y C A N+AG    AA + V +P  +D    PA  PL      EG P 
Sbjct: 70   LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPV 129

Query: 4739 QFKTQITSKIKPTIQWLREGA 4759
             F T       P  QW+  GA
Sbjct: 130  -FLT------GPRSQWVLRGA 143



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 97/364 (26%), Positives = 139/364 (38%), Gaps = 60/364 (16%)

Query: 2240 SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY 2299
            SPP F+   R    V  G  A  +C V  + +P   + +   G+ L ++ R     D   
Sbjct: 10   SPPCFLRFPR-PVRVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAE 66

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L +   +P DAG Y  +A NA G   +A ++TV               LE        
Sbjct: 67   HGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV---------------LEPPASDPEL 111

Query: 2360 EPFKRPEIPEPVTRQ-RPVF-TQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK 2417
            +P +RP +P P + +  PVF T P      +  G      CR   + +PTL   W ++  
Sbjct: 112  QPAERP-LPSPGSGEGAPVFLTGPRSQW--VLRGAEVVLTCRAGGLPEPTLY--WEKDGM 166

Query: 2418 LIE---DSSRIT----KTHDFGYVSMT--ISHVRDEDEGVYMCRASNLLGEXXXXXXXXX 2468
             ++   DSS       +  D    S+   I   R  D GVY+C A N  G          
Sbjct: 167  ALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHG---------- 216

Query: 2469 XXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528
                       H +    +Q + QP E    +PD E   P+   +   P   W  +  H 
Sbjct: 217  -----------HAQAGALLQ-VHQPPESPPADPD-EAPAPVVEPLKCAPKTFWVNEGKHA 263

Query: 2529 EARVVPVGDPSLRFEWYINGVELKMGSR--FRTTHDFGFVTLDINSVVANDAGLYMCKAI 2586
            + R   +G P    EW+  G  L    R       D GFV L +    A D GLY+C A 
Sbjct: 264  KFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAAR 322

Query: 2587 NRAG 2590
            N AG
Sbjct: 323  NSAG 326



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 116/426 (27%), Positives = 163/426 (38%), Gaps = 62/426 (14%)

Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
            +F +P++   V  G    L+  +  + +P   V W   G+ +    R     D     L 
Sbjct: 16   RFPRPVR---VVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 70

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPK 2098
            +  A   D G Y+C+A NA GEA   ++V V     L     D        EL+  ERP 
Sbjct: 71   LTAALPTDAGVYVCRARNAAGEAYAAAAVTV-----LEPPASDP-------ELQPAERPL 118

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR----- 2153
            P      G  PVFLT   S   L+ G      CR   + +P  T+ W  +G  +      
Sbjct: 119  PSPGSGEGA-PVFLTGPRSQWVLR-GAEVVLTCRAGGLPEP--TLYWEKDGMALDEVWDS 174

Query: 2154 ---AGHRYRTTHDFGY-VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
               A    R     G  +AL IL     DSG Y+C A N  G A     L+V  H+    
Sbjct: 175  SHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--HQPPES 232

Query: 2210 DTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPV 2269
                P+                 E   P + P +   +   T  V EGK A F C V  +
Sbjct: 233  PPADPD-----------------EAPAPVVEPLKCAPK---TFWVNEGKHAKFRCYV--M 270

Query: 2270 HDPNLRIEFYHNGKALQSAAR--FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCT 2327
              P   IE++  G+ L    R   +   D G+V L + +C  +D G Y   A N+ G   
Sbjct: 271  GKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTL 329

Query: 2328 SAISMTV-TAKGSIISESQRPEGLEK-IRELESAEPFKRPEIPEPVTRQRPVFTQPLQNI 2385
            SA+ + V   +       Q  EG E  I  LE   P  R  IP    R+      P +  
Sbjct: 330  SAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSR--IPTAWFREDQRLL-PCRKY 386

Query: 2386 DNIQEG 2391
            + I+EG
Sbjct: 387  EQIEEG 392



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 95/450 (21%), Positives = 172/450 (38%), Gaps = 47/450 (10%)

Query: 4362 VAKQKQTQKEVVGDKEITRK--ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQP 4419
            +A Q + Q E  G +++ R     S +  E    A    R+    V+         ++ P
Sbjct: 1309 LASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSELTP 1368

Query: 4420 CRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSA 4479
              V E + A F  E    P   + W R    +   P  ++    +  IL +R   + D  
Sbjct: 1369 LTVHEGDDATFRCEVS-PPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGD-- 1425

Query: 4480 VFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG 4539
              A     R G+   SA L V E             F    Q+V    GQ V L+ +   
Sbjct: 1426 --AGTVTLRAGSTATSARLHVRETELL---------FLRRLQDVRAEEGQDVCLEVETGR 1474

Query: 4540 TKPID-VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
                  V W++ G+ +  D R  + ++   + L I      D G Y C + +    AR  
Sbjct: 1475 VGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLARLS 1534

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
                        +P+           ++ PL+D  ++EG +  F  ++  + + T +W +
Sbjct: 1535 V-----------RPRQL--------RVLRPLEDVTISEGGSATFQLELSQEGV-TGEWAR 1574

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718
            G   + P     +      + L ++     D G   CV++ +A  +  AA+L V +    
Sbjct: 1575 GGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSG---CVSF-TADSLRCAARLIVREVP-- 1628

Query: 4719 DNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778
              +  +    D+ V EG  A F+ ++ S+    + W ++G  +  +P  ++   G   +L
Sbjct: 1629 --VTIVRGPHDLEVTEGDTATFECEL-SQALADVTWEKDGNALTPSPRLRLQALGTRRLL 1685

Query: 4779 LIGNTYEEDTGTFTCRATTA-AGQVETSAK 4807
             +      D GT++C   TA AG V  + +
Sbjct: 1686 QLRRCGPSDAGTYSCAVGTARAGPVRLTVR 1715



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 85/348 (24%), Positives = 135/348 (38%), Gaps = 39/348 (11%)

Query: 927  AHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
            A  E +   +G+    V W K G+ + AS R++   +     L + +    DAG Y CRA
Sbjct: 27   AEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRA 86

Query: 987  YNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFL 1046
             NA G+A  +A +T++         + P    ++Q  E         E        PR  
Sbjct: 87   RNAAGEAYAAAAVTVL---------EPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQ 137

Query: 1047 GPLKGTNKIVEGQSAHF-EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDI 1105
              L+G   ++  ++    E  +  + D     E + +        R +       +AL I
Sbjct: 138  WVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED-GPGASLALRI 196

Query: 1106 ASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEP 1165
             + R  DSGVY   ARNA G AQ  A +            +H+         +E+    P
Sbjct: 197  LAARLPDSGVYVCHARNAHGHAQAGALL-----------QVHQPPESPPADPDEA----P 241

Query: 1166 MYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR 1225
               +E +  +   F         V+EGK+    C +  MG P   +EW   GR +    R
Sbjct: 242  APVVEPLKCAPKTFW--------VNEGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRR 291

Query: 1226 FKTY--YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               Y   D GFV L +++  + D G Y   A N  G   ++  + V E
Sbjct: 292  RLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKE 338



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 74/363 (20%), Positives = 138/363 (38%), Gaps = 31/363 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E   E  P ++WY++   ++ S    +     +  L++     ED   F  V +    +A
Sbjct: 1012 ELSREDAP-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEF--VCDAGDDSA 1068

Query: 4493 KCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGK 4552
              +  +    +R      IV P+      +        +R +    G++   V W K+G 
Sbjct: 1069 FFTVTVTAPPER------IVHPAARSLDLHFGAPGRVELRCEVAPAGSQ---VRWYKDGL 1119

Query: 4553 KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
            +V+     ++  E  T TL +  A P+D+G+Y C       E R +A   ++      +P
Sbjct: 1120 EVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVC-------ETRHEA---ITFNVILAEP 1169

Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672
              Q  A    P    PL    VA G+ +  SC++     P V W    + ++  +  ++ 
Sbjct: 1170 PVQFLALETTP---SPL---CVAPGEPVVLSCELSRAGAPVV-WSHNGRPVQEGEGLELH 1222

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
                   L I  A P   G Y C +  + G  +++  ++V +P      P     R +  
Sbjct: 1223 AEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTR-VRS 1281

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
              G   +    ++    P ++W ++G  +      Q+   G   VL +      D G + 
Sbjct: 1282 TPGGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYL 1340

Query: 4793 CRA 4795
            C A
Sbjct: 1341 CDA 1343



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 143/389 (36%), Gaps = 45/389 (11%)

Query: 4412 IFTKKMQPCRVFEHEQARFEVEFDGEPLP-LIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            +F +++Q  R  E +    EVE         ++W R   P+ +     +        L I
Sbjct: 1450 LFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFI 1509

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
              V + D   +   + +    A+ S       + RQ R  ++ P   +T       + QL
Sbjct: 1510 HGVILADQGTYGCESHHDRTLARLSV------RPRQLR--VLRPLEDVTISEGGSATFQL 1561

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
                  VTG       W + G ++ P  +  I  +   + L++      DSG   CV+  
Sbjct: 1562 ELSQEGVTGE------WARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSG---CVSF- 1611

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
            +A   RC A  +V                  P  I+    D  V EG    F C++  + 
Sbjct: 1612 TADSLRCAARLIVR---------------EVPVTIVRGPHDLEVTEGDTATFECEL-SQA 1655

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC-VAYNSAGRVTVAAK 4709
            L  V W K    + PS   ++        L++    P D G Y C V    AG V +  +
Sbjct: 1656 LADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVR 1715

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
             +         +  L+ LR +   EG  A F+  + S+++ T +W   G  +      ++
Sbjct: 1716 ER--------TVAVLSELRSVSAREGDGATFECTV-SEVETTGRWELGGRPLRPGARVRI 1766

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              EG   +L++     ED G    +A  A
Sbjct: 1767 RQEGKKHILVLSELRAEDAGEVRFQAGPA 1795



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 89/366 (24%), Positives = 146/366 (39%), Gaps = 58/366 (15%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR-PAYEFDYVA 1369
            P F R    +  V G    L+C +  +G+    V W   G+ +    R   PA   ++  
Sbjct: 12   PCFLRFPRPVRVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSR 1429
            L L +  P D+GVY C+A N  GEA  + A+ V+         + P+   ++Q  E   R
Sbjct: 70   L-LTAALPTDAGVYVCRARNAAGEAYAAAAVTVL---------EPPASDPELQPAE---R 116

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-- 1487
               +    E     P F+T P+S + V+ G  V   C+   + +  L   W K+G  +  
Sbjct: 117  PLPSPGSGEGA---PVFLTGPRS-QWVLRGAEVVLTCRAGGLPEPTL--YWEKDGMALDE 170

Query: 1488 ---TIGHRFRP--IHD--FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540
               +     +P    D     +AL I+     DSG+Y C A N  G  +    L      
Sbjct: 171  VWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPP 230

Query: 1541 DIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERR 1600
            +   +  +EA    ++ L+                 AP      K   + EG+ A F  R
Sbjct: 231  ESPPADPDEAPAPVVEPLK----------------CAP------KTFWVNEGKHAKF--R 266

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSR--FTETNNFGFVALDIMSCLPEDSGTYTCRAINAL 1658
               +     ++EW+   +PL    R       + GFV L ++ C  +D G Y C A N+ 
Sbjct: 267  CYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSA 325

Query: 1659 GEAVTS 1664
            G+ +++
Sbjct: 326  GQTLSA 331



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 61/256 (23%), Positives = 108/256 (42%), Gaps = 36/256 (14%)

Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            +V W K+G++V       + +ED    L++     +DSG+Y C           D E   
Sbjct: 928  EVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLC---------EIDDESA- 977

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE---FSCKIVGKPLPTVQWYKGD 4660
            S   T  +P         P  II P +D++      +E     C++  +  P V+WYK  
Sbjct: 978  SFTVTVTEP---------PVRIIYP-RDEVTLIAVTLECVVLMCELSREDAP-VRWYKDG 1026

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
              ++ S+   + R      L +  A PED G++ C A + +   TV     VT P +   
Sbjct: 1027 LEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVT----VTAPPERIV 1082

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPT---IQWLREGALIPETPDFQMIHEGNNAV 4777
             PA    R + ++ G P   + ++  ++ P    ++W ++G  +  +   Q+  EG    
Sbjct: 1083 HPA---ARSLDLHFGAPG--RVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRT 1137

Query: 4778 LLIGNTYEEDTGTFTC 4793
            L + +   ED G + C
Sbjct: 1138 LTLPHAQPEDAGEYVC 1153



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 73/339 (21%), Positives = 125/339 (36%), Gaps = 20/339 (5%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D G PP F   F   V +  G  A  E   +  G+   V+ W   G+ + AS R+     
Sbjct: 7    DQGSPPCFLR-FPRPVRVVSG--AEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPAD 63

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
                 L +     TD+G Y CRA N  G+A  +  +  ++      P      + +    
Sbjct: 64   GAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLE-PPASDPELQPAERPLPSPG 122

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSG 3220
             G+ A       PV     + +W   G  +  + R   + +    +    +A  +  DS 
Sbjct: 123  SGEGA-------PVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSS 175

Query: 3221 EYVC---RAYNKYGEDFT-RATINCYGKGGVYL-ESLQPDSLAKIRELESLQGAQQQTPS 3275
             +     RA +  G     R         GVY+  +      A+   L  +    +  P+
Sbjct: 176  HFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPA 235

Query: 3276 TPSAEPPKFITQIQDVTKLV-EGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334
             P   P   +  ++   K     +  H + R   +  P+ ++EW + G+ L    R   +
Sbjct: 236  DPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMY 295

Query: 3335 HD-FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             D  G  +L +LYC  ++ G Y C A N  G+  +   L
Sbjct: 296  RDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQL 334



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 15/147 (10%)

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQN--IEGLK- 3162
            + L IL  +  DSG Y C A N  G A+    L+ V +     P          +E LK 
Sbjct: 192  LALRILAARLPDSGVYVCHARNAHGHAQAGALLQ-VHQPPESPPADPDEAPAPVVEPLKC 250

Query: 3163 --------DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAY 3213
                    +G+ A F C V+   +P+  IEW+  G+P+    R     D  G  VL + Y
Sbjct: 251  APKTFWVNEGKHAKFRCYVMGKPEPE--IEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLY 308

Query: 3214 TQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             Q  D G YVC A N  G+  +   ++
Sbjct: 309  CQAKDRGLYVCAARNSAGQTLSAVQLH 335



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 81/411 (19%), Positives = 154/411 (37%), Gaps = 42/411 (10%)

Query: 4391 EHKAQTQERVVEGPVKPSKPPIFTKKMQ----PCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            E+  +T+   +   V  ++PP+    ++    P  V   E      E      P++ W  
Sbjct: 1150 EYVCETRHEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPVV-WSH 1208

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
               P++     ++H    + +L I+      + ++   +    G    S  + V E   +
Sbjct: 1209 NGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVR 1268

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
                +V P    T   V  T G  + L   ++G     V W K+G+++    R ++ +  
Sbjct: 1269 ----VVAPEAAQT--RVRSTPGGDLELVVHLSGPGG-PVRWYKDGERLASQGRVQLEQAG 1321

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
                L +  A   D+G+Y C       +A  D+   +    + ++P           +++
Sbjct: 1322 ARQVLRVQGARSGDAGEYLC-------DAPQDSRIFL---VSVEEP--------LLVKLV 1363

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              L    V EG    F C+ V  P   V W +   ++ P    +M++      L +    
Sbjct: 1364 SELTPLTVHEGDDATFRCE-VSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQ 1422

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
              D G         AG    +A+L V + +    L  L  L+D+   EGQ    + + T 
Sbjct: 1423 LGDAGTVTL----RAGSTATSARLHVRETE----LLFLRRLQDVRAEEGQDVCLEVE-TG 1473

Query: 4747 KIKPT--IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            ++     ++W+R G  +P      M  +G+   L I      D GT+ C +
Sbjct: 1474 RVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCES 1524



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 52/201 (25%), Positives = 80/201 (39%), Gaps = 14/201 (6%)

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            +Y+ D  Q      + + E  L  + V       V EG    F C V+  P  +VTW  N
Sbjct: 1338 EYLCDAPQDSRIFLVSVEEPLLV-KLVSELTPLTVHEGDDATFRCEVSP-PDADVTWLRN 1395

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
               +      ++  N S +  L +    L D+G VT     ++G TA   RL+V E E +
Sbjct: 1396 GAVVTPGPQVEMAQNGS-SRILTLRGCQLGDAGTVTL----RAGSTATSARLHVRETELL 1450

Query: 489  VAPKFVERFSTLNVREGEPVVLNARA--VGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
                F+ R   +   EG+ V L      VG     + W + G P+  +  L +  DG   
Sbjct: 1451 ----FLRRLQDVRAEEGQDVCLEVETGRVGA-AGAVRWVRGGQPLPHDSRLSMAQDGHIH 1505

Query: 547  TLDIPRAKASDAAWYQCTAQN 567
             L I     +D   Y C + +
Sbjct: 1506 RLFIHGVILADQGTYGCESHH 1526



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 89/365 (24%), Positives = 138/365 (37%), Gaps = 57/365 (15%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G  P FL     +  +  G  A  +C V  + +P   + W   GQ++ A  R     D  
Sbjct: 9    GSPPCFLRFPRPVR-VVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGA 65

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225
               L +      D+G Y+C+A N  GEA     + V     +      P      R L +
Sbjct: 66   EHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV-----LEPPASDPELQPAERPLPS 120

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
             G              P F+T  R +  V  G      C+   + +P L  E   +G AL
Sbjct: 121  PGSGE---------GAPVFLTGPR-SQWVLRGAEVVLTCRAGGLPEPTLYWE--KDGMAL 168

Query: 2286 QSA-ARFHITFDFGY--------VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
                   H     G         ++L I      D+G Y   A NA GH  +        
Sbjct: 169  DEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQA-------- 220

Query: 2337 KGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHF 2396
             G+++   Q PE          A+P    E P PV    P+   P      + EG+ A F
Sbjct: 221  -GALLQVHQPPES-------PPADP---DEAPAPVVE--PLKCAP--KTFWVNEGKHAKF 265

Query: 2397 DCRLIPVGDPTLKVEW-FRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
             C ++  G P  ++EW +    L+ D  R+  +  D G+V + + + + +D G+Y+C A 
Sbjct: 266  RCYVM--GKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAAR 322

Query: 2455 NLLGE 2459
            N  G+
Sbjct: 323  NSAGQ 327



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 83/364 (22%), Positives = 127/364 (34%), Gaps = 42/364 (11%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F+  P+ +  V+ G     +C +  + +    V W K GQ +    R     D     
Sbjct: 12   PCFLRFPRPVR-VVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 68

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L +   +  D+G+Y CRA N  G    +  +T           +  A   ++Q  E    
Sbjct: 69   LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV---------LEPPASDPELQPAERPLP 119

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHF--ERRLIPVSDA-TLKVEWYHNNKPL 1620
               +     V    P     L+  E+    RA    E  L    D   L   W  ++  L
Sbjct: 120  SPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFAL 179

Query: 1621 KSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQ 1680
            + G    E      +AL I++    DSG Y C A NA G A    +  VH          
Sbjct: 180  QPGR--AEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP 237

Query: 1681 HEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDP 1740
             E   P +  L+   K                F +         N+  H + R   +G P
Sbjct: 238  DEAPAPVVEPLKCAPK---------------TFWV---------NEGKHAKFRCYVMGKP 273

Query: 1741 KLRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799
            +  +EW   G P+    R     D  G   L + Y   +D G Y C A N  G+ +++  
Sbjct: 274  EPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQ 333

Query: 1800 LFVQ 1803
            L V+
Sbjct: 334  LHVK 337



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 13/167 (7%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF--GMVVLEILGTKTTD 3117
            ++EG+ A +   ++  G     IEW + G+ +    R R +Y    G  VL++L  +  D
Sbjct: 257  VNEGKHAKFRCYVM--GKPEPEIEWHWEGRPLLPDRR-RLMYRDRDGGFVLKVLYCQAKD 313

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             G Y C A N  GQ   +V+L      K  + RFT  +Q++EG + G  A  EC    V 
Sbjct: 314  RGLYVCAARNSAGQTLSAVQLHV----KEPRLRFTRPLQDVEGREHG-IAVLEC---KVP 365

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +  +   W+   Q +    + + + +     L I   +  D G Y+C
Sbjct: 366  NSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC 412



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 39/162 (24%), Positives = 69/162 (42%), Gaps = 15/162 (9%)

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P   V W+ +  ++      ++ + ++G    L +      D+G   C A   S      
Sbjct: 1296 PGGPVRWYKDGERLASQ--GRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDS------ 1347

Query: 478  CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
             R+ ++  E+ +  K V   + L V EG+        V  P   +TW ++G  + P P++
Sbjct: 1348 -RIFLVSVEEPLLVKLVSELTPLTVHEGDDATFRCE-VSPPDADVTWLRNGAVVTPGPQV 1405

Query: 538  RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             +  +G +  L +   +  DA     T    AGSTAT ARL+
Sbjct: 1406 EMAQNGSSRILTLRGCQLGDAG----TVTLRAGSTATSARLH 1443



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 9/121 (7%)

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            ++   H L++  + L+DSG V+  A       + +C   +I +E  V    V     L V
Sbjct: 1589 SDGHRHRLVLNGLGLADSGCVSFTA------DSLRCAARLIVREVPVT--IVRGPHDLEV 1640

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             EG+        +      +TW+KDG  + P+P LR+   G    L + R   SDA  Y 
Sbjct: 1641 TEGDTATFECE-LSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTYS 1699

Query: 563  C 563
            C
Sbjct: 1700 C 1700



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 11/145 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +G+ + +  R++   A    VL + G ++ D+G Y C A        +SV+   +
Sbjct: 1300 VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLL 1359

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             K   +    T H        +G  A F C V P   PD  + W  NG  +    +++  
Sbjct: 1360 VKLVSELTPLTVH--------EGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQVEMA 1408

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
             +    +L +   Q  D+G    RA
Sbjct: 1409 QNGSSRILTLRGCQLGDAGTVTLRA 1433



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 96/397 (24%), Positives = 144/397 (36%), Gaps = 57/397 (14%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            S P F++    P  V  G    L+C +  +G+P   V W   G+ +    R     D   
Sbjct: 10   SPPCFLR-FPRPVRVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAE 66

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDA 1294
              L +  A   D G Y  RA N  G A+ +A V V+E     +D +          L+ A
Sbjct: 67   HGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPP--ASDPE----------LQPA 114

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
             R             AP F     +   + G  V L CR   + + T+   W  +G  + 
Sbjct: 115  ERPLPSPGSG---EGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLY--WEKDGMALD 169

Query: 1355 ----TGH-RFRPAYEFD----YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                + H   +P    D     +AL +L+    DSGVY C A N  G           A+
Sbjct: 170  EVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGH----------AQ 219

Query: 1406 KDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFE 1465
               +L+   P                  D  +    +       PK+   V EG+H  F 
Sbjct: 220  AGALLQVHQPP------------ESPPADPDEAPAPVVEPLKCAPKTFW-VNEGKHAKFR 266

Query: 1466 CKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNL 1524
            C +    +   ++EW   G+P+    R     D  G   L ++   A+D G+Y C A N 
Sbjct: 267  CYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNS 324

Query: 1525 VGTDEVSCRLTCRS-TTDIVRSTQNEAGLEQ-IQVLE 1559
             G    + +L  +       R  Q+  G E  I VLE
Sbjct: 325  AGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLE 361



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP F +  +  R   G  A+ +  + G P PVV W +    L    + S  +     + 
Sbjct: 10  SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLS--FPADGAEH 67

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            LL+    P D G Y C ARN  GEA  +  +
Sbjct: 68  GLLLTAALPTDAGVYVCRARNAAGEAYAAAAV 99



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 86/360 (23%), Positives = 139/360 (38%), Gaps = 56/360 (15%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            ++V G  A  +  V    +    V W   G+Q+ ++ R+    D     L + +    D+
Sbjct: 22   RVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDA 79

Query: 1114 GVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEIS 1173
            GVY   ARNAAGEA  +A++TV    + D                E +  E         
Sbjct: 80   GVYVCRARNAAGEAYAAAAVTVLEPPASD---------------PELQPAERPLPSPGSG 124

Query: 1174 KSKPVFVQ-PLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS---VTVGSRFKTY 1229
            +  PVF+  P S    V  G  + L CR   + +PT+   W  +G +   V   S F   
Sbjct: 125  EGAPVFLTGPRSQ--WVLRGAEVVLTCRAGGLPEPTL--YWEKDGMALDEVWDSSHFALQ 180

Query: 1230 ---YDFG---FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
                + G    +AL I+ A   D+G Y   A N  G A   A+++V +  +      +E 
Sbjct: 181  PGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEA 240

Query: 1284 AIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMR 1343
                ++ L+  A +T  V E                     G +    C +  +G     
Sbjct: 241  PAPVVEPLK-CAPKTFWVNE---------------------GKHAKFRCYV--MGKPEPE 276

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFD-YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +EW   G+P+    R     + D    L +L    +D G+Y C A N  G+ +++  L V
Sbjct: 277  IEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV 336



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 18/166 (10%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMV-IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTT 3116
            ++++EG  A +E  L     Q++  + W  +G  +  S R+R        +L++     +
Sbjct: 1638 LEVTEGDTATFECEL----SQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPS 1693

Query: 3117 DSGTYSCR-ATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
            D+GTYSC   T + G   ++V+   V           + ++++   ++G  A FECTV  
Sbjct: 1694 DAGTYSCAVGTARAGPVRLTVRERTV--------AVLSELRSVSA-REGDGATFECTVSE 1744

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            V+       W   G+P+R   R++   +    +L ++  +  D+GE
Sbjct: 1745 VETTG---RWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGE 1787



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 65/285 (22%), Positives = 117/285 (41%), Gaps = 45/285 (15%)

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLIL 4574
            S T T     V + +L R+D   T        W K+G+KV+ +    +++ DG    LIL
Sbjct: 725  SLTFTTSERVVLTCELSRVDFPAT--------WYKDGQKVE-ESELLVVKMDGRKHRLIL 775

Query: 4575 -EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
             EA  QDSG++EC    + G +            T   P         P  I++P +   
Sbjct: 776  PEAKVQDSGEFEC---RTEGVS-------AFFGVTVQDP---------PVHIVDPREHVF 816

Query: 4634 V--AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            V     + +  +C++  +  P V+WYK  + ++ S +  +        L +    P D G
Sbjct: 817  VHAITSECVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGG 875

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI-KP 4750
            +++CVA +     TV     +T        P+        VY       +  +T ++ +P
Sbjct: 876  EFQCVAGDECAYFTVT----ITDVSSWIVYPSGK------VYVAAVRLERVVLTCELCRP 925

Query: 4751 --TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
               ++W ++G  + E+P   +  E     L++     ED+G + C
Sbjct: 926  WAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLC 970



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 66  PGEPSPPIFEQIF---KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRY 122
           P E   P+ E +    K     +G +AKF   + G P P + W  +  PL+  ++  + Y
Sbjct: 237 PDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMY 295

Query: 123 NEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            ++ G   L +      D G Y C ARN  G+ + +V +
Sbjct: 296 RDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQL 334



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 48/185 (25%), Positives = 83/185 (44%), Gaps = 16/185 (8%)

Query: 4629 LKDKIVAEGQ--AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
            L+D    EGQ   +E     VG     V+W +G + +       M++    + L I    
Sbjct: 1455 LQDVRAEEGQDVCLEVETGRVGAA-GAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVI 1513

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
              D+G Y C +++        A+L V +P Q   L  L PL D+ + EG  A F+ ++ S
Sbjct: 1514 LADQGTYGCESHHD----RTLARLSV-RPRQ---LRVLRPLEDVTISEGGSATFQLEL-S 1564

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
            +   T +W R G  +   P   +  +G+   L++      D+G   C + T A  +  +A
Sbjct: 1565 QEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSG---CVSFT-ADSLRCAA 1620

Query: 4807 KLVVK 4811
            +L+V+
Sbjct: 1621 RLIVR 1625



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/91 (28%), Positives = 37/91 (40%)

Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545
           +Q   P F+     + V  G    L    +G P P + W+K G  +  +  L    DG  
Sbjct: 7   DQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAE 66

Query: 546 STLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
             L +  A  +DA  Y C A+N AG     A
Sbjct: 67  HGLLLTAALPTDAGVYVCRARNAAGEAYAAA 97



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 29/109 (26%), Positives = 55/109 (50%), Gaps = 5/109 (4%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GFVILEISPTYPEDS 3490
            + EG++A F   +    +P  ++EW+W G+ L    R   + D  G  +L++     +D 
Sbjct: 257  VNEGKHAKFRCYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDR 314

Query: 3491 GEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            G Y+C A N+ G+ ++   + V+  R  +  ++  + +EG    IA LE
Sbjct: 315  GLYVCAARNSAGQTLSAVQLHVKEPR--LRFTRPLQDVEGREHGIAVLE 361



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 77/358 (21%), Positives = 146/358 (40%), Gaps = 49/358 (13%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            WY++   ++ S    +     K  LI+ +  V+DS  F    E           + V++ 
Sbjct: 749  WYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEG----VSAFFGVTVQDP 804

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                   IV P   +    V+  + + V L  +V   +   V W K+G++V+ +    +L
Sbjct: 805  PVH----IVDPREHVF---VHAITSECVMLACEVD-REDAPVRWYKDGQEVE-ESDFVVL 855

Query: 4564 EEDGTYTLLILEA-YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
            E +G +  L+L A  P D G+++CVA    G+  C    V     +     P  K   A 
Sbjct: 856  ENEGPHRRLVLPATQPSDGGEFQCVA----GD-ECAYFTVTITDVSSWIVYPSGKVYVAA 910

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIK-PSKYFQMSRTADEYTL 4680
              +            + +  +C++  +P   V+W K G+++++ P+   Q   T     L
Sbjct: 911  VRL------------ERVVLTCELC-RPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVL 957

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAK---LKVTQPDQADNLPALTPLRDIVVYEGQP 4737
               +   ED G+Y C   + +   TV      +++  P     L A+T L  +V+     
Sbjct: 958  PAVQL--EDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVT-LECVVLM---- 1010

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
                 +++ +  P ++W ++G  + E+    +  +G    L++     ED G F C A
Sbjct: 1011 ----CELSREDAP-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDA 1063



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 10/147 (6%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYK-STHDFSYVSLDITHTYEEDSG 2844
            EG +  F C V    +P  +IEW +  +PL P   R      D  +V L + +   +D G
Sbjct: 259  EGKHAKFRCYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRG 315

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904
            +Y C A NS G   ++  L    +  + F T+  Q   G E      E ++   R   +P
Sbjct: 316  LYVCAARNSAGQTLSAVQLH-VKEPRLRF-TRPLQDVEGREHGIAVLECKVPNSR---IP 370

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHL 2931
               + + + ++P     Q+ EG V  L
Sbjct: 371  TAWFREDQRLLPCRKYEQIEEGTVRRL 397



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 2/103 (1%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D +  PV  P +   P+   + EG  A+F+  + G P P + W   G+ L+   +  +  
Sbjct: 238 DEAPAPVVEP-LKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYR 296

Query: 317 THN-HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             +    L+V   Q  D G Y   A N  G  +++  L V+ P
Sbjct: 297 DRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 339



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 9/159 (5%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C V     P V W+ + +++ +  +  +L NE  +  L++     SD G   CVA +   
Sbjct: 829 CEVDREDAP-VRWYKDGQEVEES-DFVVLENEGPHRRLVLPATQPSDGGEFQCVAGD--- 883

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
           E A+           +V P      + + +   E VVL       P   + W KDG  ++
Sbjct: 884 ECAYFTVTITDVSSWIVYPSGKVYVAAVRL---ERVVLTCELC-RPWAEVRWTKDGEEVV 939

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +P L +  +     L +P  +  D+  Y C   + + S
Sbjct: 940 ESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESAS 978



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/158 (22%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C ++    P V W+ +  ++ +     +L  +     L++      D G   C A + S 
Sbjct: 1011 CELSREDAP-VRWYKDGLEVEES-EALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDS- 1067

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT-PRITWQKDGVPI 531
              AF         E++V P       +L++  G P  +  R    P   ++ W KDG+ +
Sbjct: 1068 --AFFTVTVTAPPERIVHPAA----RSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEV 1121

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
              +  L++  +G   TL +P A+  DA  Y C  ++ A
Sbjct: 1122 EASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEA 1159



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/101 (24%), Positives = 41/101 (40%)

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            +K +  DQ      L   R + V  G  A+ K  +  +  P + W + G  +  +     
Sbjct: 1    MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSF 60

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              +G    LL+      D G + CRA  AAG+   +A + V
Sbjct: 61   PADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV 101



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 53/218 (24%), Positives = 80/218 (36%), Gaps = 12/218 (5%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491
            +R    A  E +     +P   V W   G+ L A  R     D     L ++   P D+G
Sbjct: 21   VRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAG 80

Query: 3492 EYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPE 3551
             Y+CRA N  GEA   A++ V        E Q     E  +    + EG         P 
Sbjct: 81   VYVCRARNAAGEAYAAAAVTVLEPPASDPELQ---PAERPLPSPGSGEG--------APV 129

Query: 3552 AESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND 3611
              +G   ++    ++++L+  +    E  L    D     E + +    L   R +    
Sbjct: 130  FLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED-GP 188

Query: 3612 FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
               + L I      D+G+Y C A N HG A     LQV
Sbjct: 189  GASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV 226



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIFNFGYVSLNIMHLRAED 839
           + EG++A F   +  +  P   +EW+ +GRP+    R  +    + G+V L +++ +A+D
Sbjct: 257 VNEGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKD 313

Query: 840 AGSYTVRAVNKLGEAISTASIRV 862
            G Y   A N  G+ +S   + V
Sbjct: 314 RGLYVCAARNSAGQTLSAVQLHV 336



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 35/129 (27%), Positives = 51/129 (39%), Gaps = 8/129 (6%)

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNV 502
            E     L + +    D+G   C  R+++         NVI  E  V    +E   S L V
Sbjct: 1132 EGPTRTLTLPHAQPEDAGEYVCETRHEA------ITFNVILAEPPVQFLALETTPSPLCV 1185

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              GEPVVL+        P + W  +G P+     L +H +G    L I  A  + A  Y 
Sbjct: 1186 APGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYT 1244

Query: 563  CTAQNVAGS 571
            C +    G+
Sbjct: 1245 CQSGAAPGA 1253



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 37/180 (20%), Positives = 81/180 (45%), Gaps = 16/180 (8%)

Query: 4621 APPEIIEPLKDKI---VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
            +P  I+ P +D++       + +  +C++     P   WYK  + ++ S+   +     +
Sbjct: 713  SPVHILSP-QDRVSLTFTTSERVVLTCELSRVDFPAT-WYKDGQKVEESELLVVKMDGRK 770

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE--G 4735
            + L + EA  +D G+++C    + G   V+A   VT  D   ++  + P   + V+    
Sbjct: 771  HRLILPEAKVQDSGEFEC---RTEG---VSAFFGVTVQDPPVHI--VDPREHVFVHAITS 822

Query: 4736 QPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            +      ++  +  P ++W ++G  + E+    + +EG +  L++  T   D G F C A
Sbjct: 823  ECVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVA 881



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/161 (24%), Positives = 70/161 (43%), Gaps = 14/161 (8%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM-ITNVTLS 458
            D +VTEG    F+C ++ +   +VTW  +   +    + ++ +   G   L+ +     S
Sbjct: 1637 DLEVTEGDTATFECELS-QALADVTWEKDGNALTP--SPRLRLQALGTRRLLQLRRCGPS 1693

Query: 459  DSGVVTC-VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
            D+G  +C V   ++G      RL V  +E+ VA   +    +++ REG+           
Sbjct: 1694 DAGTYSCAVGTARAGPV----RLTV--RERTVA--VLSELRSVSAREGDGATFECTVSEV 1745

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
             T    W+  G P+ P   +RI  +G    L +   +A DA
Sbjct: 1746 ETTG-RWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDA 1785



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/57 (35%), Positives = 23/57 (40%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH 4166
            PP F+  P  V V  G  A   C V G P P V+W   G  +    R     DG  H
Sbjct: 11   PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEH 67



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            TTPS L ++        C L   + +   V W HNG+P+  G  ++   +    +L I  
Sbjct: 1178 TTPSPLCVAPGEPVVLSCEL---SRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQA 1234

Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                 AGLYTC++    G  ++S  +QV
Sbjct: 1235 AGPAHAGLYTCQSGAAPGAPSLSFTVQV 1262



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            G D +  V LSG   P V W+K+G+RL +  + ++        LRV+  +  D+G Y
Sbjct: 1284 GGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEY 1339



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 2/103 (1%)

Query: 2632 MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691
            M   +G Q +P          ++V G    L+  V     P   + W K G  L    RL
Sbjct: 1    MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPP--VVVWEKGGQQLAASERL 58

Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                D     L + +    D+G+Y C+A N  GEA + A++ +
Sbjct: 59   SFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV 101



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+   + V  + G +   E +   +G+P   + W K GQ + AS R +         
Sbjct: 11  PPCFLRFPRPVRVVSGAEA--ELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 68

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           L + +    D+G Y CRA +A G A   A + V
Sbjct: 69  LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV 101



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 37/125 (29%), Positives = 50/125 (40%), Gaps = 8/125 (6%)

Query: 623 PYIPPGEEDRVYPPPQFIVPLKSVTA---MEGGKIHFETRIEPVGDPTMKIEWLKNGQSI 679
           P  PP + D    P   + PLK       +  GK H + R   +G P  +IEW   G+ +
Sbjct: 230 PESPPADPDEA--PAPVVEPLKCAPKTFWVNEGK-HAKFRCYVMGKPEPEIEWHWEGRPL 286

Query: 680 EASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERT 737
               R      R G   L +L    +D G Y C A ++ G   +   LHV  PR    R 
Sbjct: 287 LPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP 346

Query: 738 SQHPE 742
            Q  E
Sbjct: 347 LQDVE 351



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 17/156 (10%)

Query: 424 TWFINDRQIRDDYNH--------KILVNESG-NHALMITNVTLSDSGVVTCVARNKSGET 474
           TWF+N  +++ +           +  + + G  H L++  V   DSG +   +     ++
Sbjct: 646 TWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDS 705

Query: 475 AFQCRLNVIEKE-QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
           A    L + E    +++P+  +R S L     E VVL         P  TW KDG  +  
Sbjct: 706 A---ALTIQESPVHILSPQ--DRVS-LTFTTSERVVLTCELSRVDFPA-TWYKDGQKVEE 758

Query: 534 NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           +  L +  DG    L +P AK  D+  ++C  + V+
Sbjct: 759 SELLVVKMDGRKHRLILPEAKVQDSGEFECRTEGVS 794



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 36/169 (21%), Positives = 63/169 (37%), Gaps = 13/169 (7%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + EG  A +   + P       + W  NG  +    ++         +L + G +  D+G
Sbjct: 1371 VHEGDDATFRCEVSPPDAD---VTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAG 1427

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
            T + RA    G    S +L      +  +  F   +Q++   ++GQ    E     V   
Sbjct: 1428 TVTLRA----GSTATSARLHV----RETELLFLRRLQDVRA-EEGQDVCLEVETGRVGAA 1478

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
               + W   GQP+ H +R+    D     L I      D G Y C +++
Sbjct: 1479 G-AVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHH 1526



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/75 (30%), Positives = 35/75 (46%)

Query: 788 AHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
           A  E +   + +P   V W K G+ + AS R++   +     L +      DAG Y  RA
Sbjct: 27  AEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRA 86

Query: 848 VNKLGEAISTASIRV 862
            N  GEA + A++ V
Sbjct: 87  RNAAGEAYAAAAVTV 101



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 5/85 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKL--TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P+ +IEW++ G+ L    R  +    D GFV L ++    +D G+Y C A N  G+  T 
Sbjct: 273  PEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQ--TL 329

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLE 3023
            S V    K+  +  T+  +  EG E
Sbjct: 330  SAVQLHVKEPRLRFTRPLQDVEGRE 354



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 3/70 (4%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD-FGYVAMNFGWVYPEDSGE 4045
            E +  KF C +  +G P  ++EW + G+PLL   R     D  G   +   +   +D G 
Sbjct: 259  EGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGL 316

Query: 4046 YLCRATNLYG 4055
            Y+C A N  G
Sbjct: 317  YVCAARNSAG 326



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V   R  FT+PLQ+++  + G  A  +C+   V +  +   WFR ++ +    +  +  +
Sbjct: 336  VKEPRLRFTRPLQDVEGREHG-IAVLECK---VPNSRIPTAWFREDQRLLPCRKYEQIEE 391

Query: 2431 FGYVSMTISHVRDEDEGVYMC 2451
                 + I  ++ +D+G+Y+C
Sbjct: 392  GTVRRLIIHRLKADDDGIYLC 412



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 9/102 (8%)

Query: 1172 ISKSKPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            +S  +P+ V+ +S   P  V EG +    C + P   P   V W  NG  VT G + +  
Sbjct: 1352 VSVEEPLLVKLVSELTPLTVHEGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQVEMA 1408

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             +     L +      D G  T+RA    GS  TSA + V E
Sbjct: 1409 QNGSSRILTLRGCQLGDAGTVTLRA----GSTATSARLHVRE 1446



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            +P   + W   G+ L    R    +D     L L      D+G+Y C+A N  GEA+ ++
Sbjct: 38   EPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAA 97

Query: 3000 TV 3001
             V
Sbjct: 98   AV 99



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1185 NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244
            +P  V+ G+ + L C L   G P   V W HNGR V  G   + + +     L I  A  
Sbjct: 1181 SPLCVAPGEPVVLSCELSRAGAP---VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGP 1237

Query: 1245 ADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            A  G YT ++    G+   S  V+V E
Sbjct: 1238 AHAGLYTCQSGAAPGAPSLSFTVQVAE 1264



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V W   G+PL   SR+    D     L I GV   D G Y C++   H + T++ +L V+
Sbjct: 1481 VRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCES---HHDRTLA-RLSVR 1536

Query: 3651 GRQGIILEPQLPSHFKSGTESIQKLE 3676
             RQ  +L P        G  +  +LE
Sbjct: 1537 PRQLRVLRPLEDVTISEGGSATFQLE 1562



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 15/48 (31%), Positives = 26/48 (54%)

Query: 1743 RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            +V W ++G+ +EAS+ L    +     L + +  PED+G Y C   +E
Sbjct: 1111 QVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHE 1158



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 8/96 (8%)

Query: 1845 RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAAL 1904
            + +++L  P  + EG  A + C + P   P+  V W  NG V+  G +   + +     L
Sbjct: 1361 KLVSELT-PLTVHEGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQVEMAQNGSSRIL 1416

Query: 1905 DILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             +      D+G  T +A    G   +S RL+V+  E
Sbjct: 1417 TLRGCQLGDAGTVTLRA----GSTATSARLHVRETE 1448



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P  I + P + ++ EG  A F+ +LS      VTW K+G  L  S +  +        L+
Sbjct: 1628 PVTIVRGPHDLEVTEGDTATFECELS-QALADVTWEKDGNALTPSPRLRLQALGTRRLLQ 1686

Query: 325  VRNTQKSDSGHYT 337
            +R    SD+G Y+
Sbjct: 1687 LRRCGPSDAGTYS 1699



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQA 1387
            V L C + P G Q   V W+ +G  ++     +   E     L L    PED+G Y C+ 
Sbjct: 1099 VELRCEVAPAGSQ---VRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCET 1155

Query: 1388 TNQ 1390
             ++
Sbjct: 1156 RHE 1158



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
            +F   ++D+R  E Q    E     VG     V W+R G P+   +RL+   D     L 
Sbjct: 1450 LFLRRLQDVRAEEGQDVCLEVETGRVGAAGA-VRWVRGGQPLPHDSRLSMAQDGHIHRLF 1508

Query: 1772 MKYVNPEDSGTYTCRA 1787
            +  V   D GTY C +
Sbjct: 1509 IHGVILADQGTYGCES 1524



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 3/81 (3%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V  G PV L   L+    P   V W  NGRPVQ+G   +   +     L I  A     G
Sbjct: 1185 VAPGEPVVLSCELSRAGAP---VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAG 1241

Query: 2049 TYMCKATNAVGEAVTTSSVKV 2069
             Y C++  A G    + +V+V
Sbjct: 1242 LYTCQSGAAPGAPSLSFTVQV 1262



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            + EG DA F+ ++S  P   VTW +NG  +    + E+    +   L +R  Q  D+G  
Sbjct: 1371 VHEGDDATFRCEVSP-PDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTV 1429

Query: 337  TLLA 340
            TL A
Sbjct: 1430 TLRA 1433



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 2/46 (4%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTA 148
            V W R+ A L   +KY MR +  T   SL+I  + P D+G Y C A
Sbjct: 1839 VCWLREGAELCPGDKYEMRSHGPTH--SLVIHDVRPEDQGTYCCQA 1882



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 2/98 (2%)

Query: 3828 TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887
            +PP F+   +   V        +C V  +  P   + W + G+ L +  R     D    
Sbjct: 10   SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPV--VVWEKGGQQLAASERLSFPADGAEH 67

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             L +      D+G Y+CRA N  GE +  A ++  + P
Sbjct: 68   GLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPP 105


>EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform C
            protein.
          Length = 1544

 Score =  120 bits (290), Expect = 1e-25
 Identities = 117/429 (27%), Positives = 176/429 (41%), Gaps = 39/429 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP F +  +P RV    +A  +    GEP P++ W +    +  S          +  L+
Sbjct: 11   PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 70

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVV-------------EEKRRQGRGGIVPPSF 4516
            +      D+ V+   A N  G A  +A + V             E        G   P F
Sbjct: 71   LTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVF 130

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP--DIRNKILE----EDG--- 4567
                ++  V  G  V L  +  G     +YW K+G  +    D  +  L+    EDG   
Sbjct: 131  LTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGA 190

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            +  L IL A   DSG Y C A N+ G A+  A   V  P       P      AP  ++E
Sbjct: 191  SLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPD----EAPAPVVE 246

Query: 4628 PLK--DKI--VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-YTLRI 4682
            PLK   K   V EG+  +F C ++GKP P ++W+   + + P +   M R  D  + L++
Sbjct: 247  PLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKV 306

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                 +D G Y C A NSAG+   A +L V +P     L    PL+D+   E   A  + 
Sbjct: 307  LYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP----RLRFTRPLQDVEGREHGIAVLEC 362

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            ++ +   PT  W RE   +     ++ I EG    L+I     +D G + C      G+V
Sbjct: 363  KVPNSRIPT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE---MRGRV 418

Query: 4803 ETSAKLVVK 4811
             T A + VK
Sbjct: 419  RTVANVTVK 427



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 90/338 (26%), Positives = 133/338 (39%), Gaps = 34/338 (10%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           SPP   + PR  ++  GA+A+ +  + G P P V W K GQ+L  S +           L
Sbjct: 10  SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +     +D+G Y   A N  G    +  + V  P  S           D + +  E  +
Sbjct: 70  LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAS-----------DPELQPAERPL 118

Query: 384 EISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD--DYNHKI 440
                   AP F+   + + V  G      CR  G P P + W  +   + +  D +H  
Sbjct: 119 PSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFA 178

Query: 441 LVN---ESG---NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV--------IEKE 486
           L     E G   + AL I    L DSGV  C ARN  G       L V         + +
Sbjct: 179 LQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPD 238

Query: 487 QVVAPKFVERFS----TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542
           +  AP  VE       T  V EG+        +G P P I W  +G P++P+    ++ D
Sbjct: 239 EAPAP-VVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRD 297

Query: 543 -GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             G   L +   +A D   Y C A+N AG T +  +L+
Sbjct: 298 RDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLH 335



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 75/307 (24%), Positives = 112/307 (36%), Gaps = 31/307 (10%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL--INSNKHEIITTHN---- 319
           P     PR+  +  GA+     +  G P P + W K+G  L  +  + H  +        
Sbjct: 128 PVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDG 187

Query: 320 ---HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
                 LR+   +  DSG Y   A N +G       L V  P ES   D       D   
Sbjct: 188 PGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP------DEAP 241

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
               E ++ + K              V EGK  +F C V G+P PE+ W    R +  D 
Sbjct: 242 APVVEPLKCAPKTFW-----------VNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDR 290

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER 496
              +  +  G   L +      D G+  C ARN +G+T    +L+V E       +F   
Sbjct: 291 RRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRL----RFTRP 346

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
              +  RE    VL  +   +  P   W ++   ++P  +     +G    L I R KA 
Sbjct: 347 LQDVEGREHGIAVLECKVPNSRIP-TAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKAD 405

Query: 557 DAAWYQC 563
           D   Y C
Sbjct: 406 DDGIYLC 412



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 91/370 (24%), Positives = 149/370 (40%), Gaps = 36/370 (9%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++WY++   ++ S   Q+        L +     ED+  +  V E R      + N+++ 
Sbjct: 1113 VRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEY--VCETRHEAI--TFNVILA 1168

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E   Q       PS       + V  G+ V L  +++      V W  NG+ VQ     +
Sbjct: 1169 EPPVQFLALETTPS------PLCVAPGEPVVLSCELSRAGA-PVVWSHNGRPVQEGEGLE 1221

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +  E     L I  A P  +G Y C +  + G          SL  T    +P  +   A
Sbjct: 1222 LHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAP--------SLSFTVQVAEPPVRVV-A 1272

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P      ++      G  +E    + G   P V+WYK  + +      Q+ +      LR
Sbjct: 1273 PEAAQTRVRS---TPGGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLR 1328

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            +  A   D G+Y C A   + R+ + +   V +P     +  LTPL    V+EG  A F+
Sbjct: 1329 VQGARSGDAGEYLCDAPQDS-RIFLVS---VEEPLLVKLVSELTPL---TVHEGDDATFR 1381

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             ++ S     + WLR GA++   P  +M   G++ +L +      D GT T R    AG 
Sbjct: 1382 CEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLR----AGS 1436

Query: 4802 VETSAKLVVK 4811
              TSA+L V+
Sbjct: 1437 TATSARLHVR 1446



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 101/459 (22%), Positives = 162/459 (35%), Gaps = 51/459 (11%)

Query: 4370 KEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQAR 4429
            +   G+      +T  E    + + Q  ER +  P      P+F    +   V    +  
Sbjct: 87   RNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVV 146

Query: 4430 FEVEFDGEPLPLIKWYRENFPIK---NSPDFQIHTFSTKS------ILIIRQVFVEDSAV 4480
                  G P P + W ++   +    +S  F +     +        L I    + DS V
Sbjct: 147  LTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGV 206

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRR-------QGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
            +   A N  G A+  A L V +          +    +V P      +   V  G+  + 
Sbjct: 207  YVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEP-LKCAPKTFWVNEGKHAKF 265

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECVAINSA 4592
               V G    ++ W   G+ + PD R  +  + DG + L +L    +D G Y C A NSA
Sbjct: 266  RCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSA 325

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
            G+     +  V  P  +                  PL+D    E       CK+    +P
Sbjct: 326  GQTLSAVQLHVKEPRLR---------------FTRPLQDVEGREHGIAVLECKVPNSRIP 370

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            T  W++ D+ + P + ++         L I     +D+G Y C      GRV   A + V
Sbjct: 371  TA-WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC---EMRGRVRTVANVTV 426

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
              P     LP     R + V EG+ A    + T +     +W R+G    E P       
Sbjct: 427  KGP-ILKRLP-----RKLDVLEGENAVLLVE-TLEAGVEGRWSRDG---EELPVICQSSS 476

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G+   L++     ED G      T + G   T+  L VK
Sbjct: 477  GHMHALVLPGVTREDAG----EVTFSLGNSRTTTLLRVK 511



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 103/376 (27%), Positives = 144/376 (38%), Gaps = 64/376 (17%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F    + +RV     A  E + + +G+P   V W + G  + AS RL+   D     L
Sbjct: 12   PCFLRFPRPVRVVSGAEA--ELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +    P D+G Y CRA N  GEA  ++ + V    +   E Q                 
Sbjct: 70   LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPA--------------- 114

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTK--LSEGQSAHYECRIEPYPDPNMRVEWYFNG---- 1884
            +R      +   AP F+T   GP    +  G      CR    P+P +   W  +G    
Sbjct: 115  ERPLPSPGSGEGAPVFLT---GPRSQWVLRGAEVVLTCRAGGLPEPTL--YWEKDGMALD 169

Query: 1885 KVLQSGH----RYRTSNDFGFA-ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-QS 1938
            +V  S H      R  +  G + AL IL     DSG Y C A N  G A +   L V Q 
Sbjct: 170  EVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQP 229

Query: 1939 KESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLE 1998
             ES   D     A                       V +P    P K   V EG   H +
Sbjct: 230  PESPPADPDEAPA----------------------PVVEPLKCAP-KTFWVNEGK--HAK 264

Query: 1999 ATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
                 +  P   +EW+  GRP+    R       D G+V L +LY  A+D G Y+C A N
Sbjct: 265  FRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARN 323

Query: 2057 AVGEAVTTSSVKVDAK 2072
            + G+  T S+V++  K
Sbjct: 324  SAGQ--TLSAVQLHVK 337



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 97/381 (25%), Positives = 143/381 (37%), Gaps = 59/381 (15%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            + G+PP F   P  + +   + A  +C  + + +    V W   G+ L    R+    D 
Sbjct: 7    DQGSPPCFLRFPRPVRVVSGAEAELKC--VVLGEPPPVVVWEKGGQQLAASERLSFPADG 64

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
                L +      DAG+Y C+A N  GEA  +  + V       LEP       +    +
Sbjct: 65   AEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV-------LEPP------ASDPEL 111

Query: 3673 QKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT------ 3726
            Q  E  L               P F    +    V  G  V   CR   + +PT      
Sbjct: 112  QPAERPLPS------PGSGEGAPVFLTGPRSQW-VLRGAEVVLTCRAGGLPEPTLYWEKD 164

Query: 3727 -MRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             M +D   +   FA             +AL I      D+G Y C A N  G A   A  
Sbjct: 165  GMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGA-- 222

Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESE 3845
                   ++   Q P+    +  +       + AP  EP+   P       K+  V E +
Sbjct: 223  -------LLQVHQPPESPPADPDE-------APAPVVEPLKCAP-------KTFWVNEGK 261

Query: 3846 GVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHR--YRTVYDMGFVSLDILYVYAEDSGEY 3902
              +F C V  K +P+  IEW+  G+ LLP   R  YR   D GFV L +LY  A+D G Y
Sbjct: 262  HAKFRCYVMGKPEPE--IEWHWEGRPLLPDRRRLMYRD-RDGGFV-LKVLYCQAKDRGLY 317

Query: 3903 ICRAVNDFGEDFTKATISCKK 3923
            +C A N  G+  +   +  K+
Sbjct: 318  VCAARNSAGQTLSAVQLHVKE 338



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 45/141 (31%), Positives = 62/141 (43%), Gaps = 9/141 (6%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            +PP  +   +   V  G   E  C ++G+P P V W KG + +  S+         E+ L
Sbjct: 10   SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN--LPALTPLRDIVVYEGQPA 4738
             ++ A P D G Y C A N+AG    AA + V +P  +D    PA  PL      EG P 
Sbjct: 70   LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPV 129

Query: 4739 QFKTQITSKIKPTIQWLREGA 4759
             F T       P  QW+  GA
Sbjct: 130  -FLT------GPRSQWVLRGA 143



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 97/364 (26%), Positives = 139/364 (38%), Gaps = 60/364 (16%)

Query: 2240 SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY 2299
            SPP F+   R    V  G  A  +C V  + +P   + +   G+ L ++ R     D   
Sbjct: 10   SPPCFLRFPR-PVRVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAE 66

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L +   +P DAG Y  +A NA G   +A ++TV               LE        
Sbjct: 67   HGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV---------------LEPPASDPEL 111

Query: 2360 EPFKRPEIPEPVTRQ-RPVF-TQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK 2417
            +P +RP +P P + +  PVF T P      +  G      CR   + +PTL   W ++  
Sbjct: 112  QPAERP-LPSPGSGEGAPVFLTGPRSQW--VLRGAEVVLTCRAGGLPEPTLY--WEKDGM 166

Query: 2418 LIE---DSSRIT----KTHDFGYVSMT--ISHVRDEDEGVYMCRASNLLGEXXXXXXXXX 2468
             ++   DSS       +  D    S+   I   R  D GVY+C A N  G          
Sbjct: 167  ALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHG---------- 216

Query: 2469 XXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528
                       H +    +Q + QP E    +PD E   P+   +   P   W  +  H 
Sbjct: 217  -----------HAQAGALLQ-VHQPPESPPADPD-EAPAPVVEPLKCAPKTFWVNEGKHA 263

Query: 2529 EARVVPVGDPSLRFEWYINGVELKMGSR--FRTTHDFGFVTLDINSVVANDAGLYMCKAI 2586
            + R   +G P    EW+  G  L    R       D GFV L +    A D GLY+C A 
Sbjct: 264  KFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAAR 322

Query: 2587 NRAG 2590
            N AG
Sbjct: 323  NSAG 326



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 116/426 (27%), Positives = 163/426 (38%), Gaps = 62/426 (14%)

Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
            +F +P++   V  G    L+  +  + +P   V W   G+ +    R     D     L 
Sbjct: 16   RFPRPVR---VVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 70

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPK 2098
            +  A   D G Y+C+A NA GEA   ++V V     L     D        EL+  ERP 
Sbjct: 71   LTAALPTDAGVYVCRARNAAGEAYAAAAVTV-----LEPPASDP-------ELQPAERPL 118

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR----- 2153
            P      G  PVFLT   S   L+ G      CR   + +P  T+ W  +G  +      
Sbjct: 119  PSPGSGEGA-PVFLTGPRSQWVLR-GAEVVLTCRAGGLPEP--TLYWEKDGMALDEVWDS 174

Query: 2154 ---AGHRYRTTHDFGY-VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
               A    R     G  +AL IL     DSG Y+C A N  G A     L+V  H+    
Sbjct: 175  SHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--HQPPES 232

Query: 2210 DTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPV 2269
                P+                 E   P + P +   +   T  V EGK A F C V  +
Sbjct: 233  PPADPD-----------------EAPAPVVEPLKCAPK---TFWVNEGKHAKFRCYV--M 270

Query: 2270 HDPNLRIEFYHNGKALQSAAR--FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCT 2327
              P   IE++  G+ L    R   +   D G+V L + +C  +D G Y   A N+ G   
Sbjct: 271  GKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTL 329

Query: 2328 SAISMTV-TAKGSIISESQRPEGLEK-IRELESAEPFKRPEIPEPVTRQRPVFTQPLQNI 2385
            SA+ + V   +       Q  EG E  I  LE   P  R  IP    R+      P +  
Sbjct: 330  SAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSR--IPTAWFREDQRLL-PCRKY 386

Query: 2386 DNIQEG 2391
            + I+EG
Sbjct: 387  EQIEEG 392



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 85/348 (24%), Positives = 135/348 (38%), Gaps = 39/348 (11%)

Query: 927  AHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
            A  E +   +G+    V W K G+ + AS R++   +     L + +    DAG Y CRA
Sbjct: 27   AEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRA 86

Query: 987  YNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFL 1046
             NA G+A  +A +T++         + P    ++Q  E         E        PR  
Sbjct: 87   RNAAGEAYAAAAVTVL---------EPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQ 137

Query: 1047 GPLKGTNKIVEGQSAHF-EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDI 1105
              L+G   ++  ++    E  +  + D     E + +        R +       +AL I
Sbjct: 138  WVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED-GPGASLALRI 196

Query: 1106 ASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEP 1165
             + R  DSGVY   ARNA G AQ  A +            +H+         +E+    P
Sbjct: 197  LAARLPDSGVYVCHARNAHGHAQAGALL-----------QVHQPPESPPADPDEA----P 241

Query: 1166 MYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR 1225
               +E +  +   F         V+EGK+    C +  MG P   +EW   GR +    R
Sbjct: 242  APVVEPLKCAPKTFW--------VNEGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRR 291

Query: 1226 FKTY--YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               Y   D GFV L +++  + D G Y   A N  G   ++  + V E
Sbjct: 292  RLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKE 338



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 74/363 (20%), Positives = 138/363 (38%), Gaps = 31/363 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E   E  P ++WY++   ++ S    +     +  L++     ED   F  V +    +A
Sbjct: 1013 ELSREDAP-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEF--VCDAGDDSA 1069

Query: 4493 KCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGK 4552
              +  +    +R      IV P+      +        +R +    G++   V W K+G 
Sbjct: 1070 FFTVTVTAPPER------IVHPAARSLDLHFGAPGRVELRCEVAPAGSQ---VRWYKDGL 1120

Query: 4553 KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
            +V+     ++  E  T TL +  A P+D+G+Y C       E R +A   ++      +P
Sbjct: 1121 EVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVC-------ETRHEA---ITFNVILAEP 1170

Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672
              Q  A    P    PL    VA G+ +  SC++     P V W    + ++  +  ++ 
Sbjct: 1171 PVQFLALETTP---SPL---CVAPGEPVVLSCELSRAGAPVV-WSHNGRPVQEGEGLELH 1223

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
                   L I  A P   G Y C +  + G  +++  ++V +P      P     R +  
Sbjct: 1224 AEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTR-VRS 1282

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
              G   +    ++    P ++W ++G  +      Q+   G   VL +      D G + 
Sbjct: 1283 TPGGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYL 1341

Query: 4793 CRA 4795
            C A
Sbjct: 1342 CDA 1344



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 89/366 (24%), Positives = 146/366 (39%), Gaps = 58/366 (15%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR-PAYEFDYVA 1369
            P F R    +  V G    L+C +  +G+    V W   G+ +    R   PA   ++  
Sbjct: 12   PCFLRFPRPVRVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSR 1429
            L L +  P D+GVY C+A N  GEA  + A+ V+         + P+   ++Q  E   R
Sbjct: 70   L-LTAALPTDAGVYVCRARNAAGEAYAAAAVTVL---------EPPASDPELQPAE---R 116

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-- 1487
               +    E     P F+T P+S + V+ G  V   C+   + +  L   W K+G  +  
Sbjct: 117  PLPSPGSGEGA---PVFLTGPRS-QWVLRGAEVVLTCRAGGLPEPTL--YWEKDGMALDE 170

Query: 1488 ---TIGHRFRP--IHD--FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540
               +     +P    D     +AL I+     DSG+Y C A N  G  +    L      
Sbjct: 171  VWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPP 230

Query: 1541 DIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERR 1600
            +   +  +EA    ++ L+                 AP      K   + EG+ A F  R
Sbjct: 231  ESPPADPDEAPAPVVEPLK----------------CAP------KTFWVNEGKHAKF--R 266

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSR--FTETNNFGFVALDIMSCLPEDSGTYTCRAINAL 1658
               +     ++EW+   +PL    R       + GFV L ++ C  +D G Y C A N+ 
Sbjct: 267  CYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSA 325

Query: 1659 GEAVTS 1664
            G+ +++
Sbjct: 326  GQTLSA 331



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 61/256 (23%), Positives = 108/256 (42%), Gaps = 36/256 (14%)

Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            +V W K+G++V       + +ED    L++     +DSG+Y C           D E   
Sbjct: 929  EVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLC---------EIDDESA- 978

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE---FSCKIVGKPLPTVQWYKGD 4660
            S   T  +P         P  II P +D++      +E     C++  +  P V+WYK  
Sbjct: 979  SFTVTVTEP---------PVRIIYP-RDEVTLIAVTLECVVLMCELSREDAP-VRWYKDG 1027

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
              ++ S+   + R      L +  A PED G++ C A + +   TV     VT P +   
Sbjct: 1028 LEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVT----VTAPPERIV 1083

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPT---IQWLREGALIPETPDFQMIHEGNNAV 4777
             PA    R + ++ G P   + ++  ++ P    ++W ++G  +  +   Q+  EG    
Sbjct: 1084 HPA---ARSLDLHFGAPG--RVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRT 1138

Query: 4778 LLIGNTYEEDTGTFTC 4793
            L + +   ED G + C
Sbjct: 1139 LTLPHAQPEDAGEYVC 1154



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 73/339 (21%), Positives = 125/339 (36%), Gaps = 20/339 (5%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D G PP F   F   V +  G  A  E   +  G+   V+ W   G+ + AS R+     
Sbjct: 7    DQGSPPCFLR-FPRPVRVVSG--AEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPAD 63

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
                 L +     TD+G Y CRA N  G+A  +  +  ++      P      + +    
Sbjct: 64   GAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLE-PPASDPELQPAERPLPSPG 122

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSG 3220
             G+ A       PV     + +W   G  +  + R   + +    +    +A  +  DS 
Sbjct: 123  SGEGA-------PVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSS 175

Query: 3221 EYVC---RAYNKYGEDFT-RATINCYGKGGVYL-ESLQPDSLAKIRELESLQGAQQQTPS 3275
             +     RA +  G     R         GVY+  +      A+   L  +    +  P+
Sbjct: 176  HFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPA 235

Query: 3276 TPSAEPPKFITQIQDVTKLV-EGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334
             P   P   +  ++   K     +  H + R   +  P+ ++EW + G+ L    R   +
Sbjct: 236  DPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMY 295

Query: 3335 HD-FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             D  G  +L +LYC  ++ G Y C A N  G+  +   L
Sbjct: 296  RDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQL 334



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 15/147 (10%)

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQN--IEGLK- 3162
            + L IL  +  DSG Y C A N  G A+    L+ V +     P          +E LK 
Sbjct: 192  LALRILAARLPDSGVYVCHARNAHGHAQAGALLQ-VHQPPESPPADPDEAPAPVVEPLKC 250

Query: 3163 --------DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAY 3213
                    +G+ A F C V+   +P+  IEW+  G+P+    R     D  G  VL + Y
Sbjct: 251  APKTFWVNEGKHAKFRCYVMGKPEPE--IEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLY 308

Query: 3214 TQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             Q  D G YVC A N  G+  +   ++
Sbjct: 309  CQAKDRGLYVCAARNSAGQTLSAVQLH 335



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 81/411 (19%), Positives = 154/411 (37%), Gaps = 42/411 (10%)

Query: 4391 EHKAQTQERVVEGPVKPSKPPIFTKKMQ----PCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            E+  +T+   +   V  ++PP+    ++    P  V   E      E      P++ W  
Sbjct: 1151 EYVCETRHEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPVV-WSH 1209

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
               P++     ++H    + +L I+      + ++   +    G    S  + V E   +
Sbjct: 1210 NGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVR 1269

Query: 4507 GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
                +V P    T   V  T G  + L   ++G     V W K+G+++    R ++ +  
Sbjct: 1270 ----VVAPEAAQT--RVRSTPGGDLELVVHLSGPGG-PVRWYKDGERLASQGRVQLEQAG 1322

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
                L +  A   D+G+Y C       +A  D+   +    + ++P           +++
Sbjct: 1323 ARQVLRVQGARSGDAGEYLC-------DAPQDSRIFL---VSVEEP--------LLVKLV 1364

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              L    V EG    F C+ V  P   V W +   ++ P    +M++      L +    
Sbjct: 1365 SELTPLTVHEGDDATFRCE-VSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQ 1423

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
              D G         AG    +A+L V + +    L  L  L+D+   EGQ    + + T 
Sbjct: 1424 LGDAGTVTL----RAGSTATSARLHVRETE----LLFLRRLQDVRAEEGQDVCLEVE-TG 1474

Query: 4747 KIKPT--IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            ++     ++W+R G  +P      M  +G+   L I      D GT+ C +
Sbjct: 1475 RVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCES 1525



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 52/201 (25%), Positives = 80/201 (39%), Gaps = 14/201 (6%)

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            +Y+ D  Q      + + E  L  + V       V EG    F C V+  P  +VTW  N
Sbjct: 1339 EYLCDAPQDSRIFLVSVEEPLLV-KLVSELTPLTVHEGDDATFRCEVSP-PDADVTWLRN 1396

Query: 429  DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
               +      ++  N S +  L +    L D+G VT     ++G TA   RL+V E E +
Sbjct: 1397 GAVVTPGPQVEMAQNGS-SRILTLRGCQLGDAGTVTL----RAGSTATSARLHVRETELL 1451

Query: 489  VAPKFVERFSTLNVREGEPVVLNARA--VGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
                F+ R   +   EG+ V L      VG     + W + G P+  +  L +  DG   
Sbjct: 1452 ----FLRRLQDVRAEEGQDVCLEVETGRVGA-AGAVRWVRGGQPLPHDSRLSMAQDGHIH 1506

Query: 547  TLDIPRAKASDAAWYQCTAQN 567
             L I     +D   Y C + +
Sbjct: 1507 RLFIHGVILADQGTYGCESHH 1527



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 89/365 (24%), Positives = 138/365 (37%), Gaps = 57/365 (15%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G  P FL     +  +  G  A  +C V  + +P   + W   GQ++ A  R     D  
Sbjct: 9    GSPPCFLRFPRPVR-VVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGA 65

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225
               L +      D+G Y+C+A N  GEA     + V     +      P      R L +
Sbjct: 66   EHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV-----LEPPASDPELQPAERPLPS 120

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
             G              P F+T  R +  V  G      C+   + +P L  E   +G AL
Sbjct: 121  PGSGE---------GAPVFLTGPR-SQWVLRGAEVVLTCRAGGLPEPTLYWE--KDGMAL 168

Query: 2286 QSA-ARFHITFDFGY--------VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
                   H     G         ++L I      D+G Y   A NA GH  +        
Sbjct: 169  DEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQA-------- 220

Query: 2337 KGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHF 2396
             G+++   Q PE          A+P    E P PV    P+   P      + EG+ A F
Sbjct: 221  -GALLQVHQPPES-------PPADP---DEAPAPVVE--PLKCAP--KTFWVNEGKHAKF 265

Query: 2397 DCRLIPVGDPTLKVEW-FRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
             C ++  G P  ++EW +    L+ D  R+  +  D G+V + + + + +D G+Y+C A 
Sbjct: 266  RCYVM--GKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAAR 322

Query: 2455 NLLGE 2459
            N  G+
Sbjct: 323  NSAGQ 327



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 83/364 (22%), Positives = 127/364 (34%), Gaps = 42/364 (11%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F+  P+ +  V+ G     +C +  + +    V W K GQ +    R     D     
Sbjct: 12   PCFLRFPRPVR-VVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 68

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L +   +  D+G+Y CRA N  G    +  +T           +  A   ++Q  E    
Sbjct: 69   LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV---------LEPPASDPELQPAERPLP 119

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHF--ERRLIPVSDA-TLKVEWYHNNKPL 1620
               +     V    P     L+  E+    RA    E  L    D   L   W  ++  L
Sbjct: 120  SPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFAL 179

Query: 1621 KSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQ 1680
            + G    E      +AL I++    DSG Y C A NA G A    +  VH          
Sbjct: 180  QPGR--AEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP 237

Query: 1681 HEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDP 1740
             E   P +  L+   K                F +         N+  H + R   +G P
Sbjct: 238  DEAPAPVVEPLKCAPK---------------TFWV---------NEGKHAKFRCYVMGKP 273

Query: 1741 KLRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799
            +  +EW   G P+    R     D  G   L + Y   +D G Y C A N  G+ +++  
Sbjct: 274  EPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQ 333

Query: 1800 LFVQ 1803
            L V+
Sbjct: 334  LHVK 337



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 13/167 (7%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF--GMVVLEILGTKTTD 3117
            ++EG+ A +   ++  G     IEW + G+ +    R R +Y    G  VL++L  +  D
Sbjct: 257  VNEGKHAKFRCYVM--GKPEPEIEWHWEGRPLLPDRR-RLMYRDRDGGFVLKVLYCQAKD 313

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             G Y C A N  GQ   +V+L      K  + RFT  +Q++EG + G  A  EC    V 
Sbjct: 314  RGLYVCAARNSAGQTLSAVQLHV----KEPRLRFTRPLQDVEGREHG-IAVLEC---KVP 365

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +  +   W+   Q +    + + + +     L I   +  D G Y+C
Sbjct: 366  NSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC 412



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 39/162 (24%), Positives = 69/162 (42%), Gaps = 15/162 (9%)

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P   V W+ +  ++      ++ + ++G    L +      D+G   C A   S      
Sbjct: 1297 PGGPVRWYKDGERLASQ--GRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDS------ 1348

Query: 478  CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
             R+ ++  E+ +  K V   + L V EG+        V  P   +TW ++G  + P P++
Sbjct: 1349 -RIFLVSVEEPLLVKLVSELTPLTVHEGDDATFRCE-VSPPDADVTWLRNGAVVTPGPQV 1406

Query: 538  RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             +  +G +  L +   +  DA     T    AGSTAT ARL+
Sbjct: 1407 EMAQNGSSRILTLRGCQLGDAG----TVTLRAGSTATSARLH 1444



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 11/145 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +G+ + +  R++   A    VL + G ++ D+G Y C A        +SV+   +
Sbjct: 1301 VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLL 1360

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             K   +    T H        +G  A F C V P   PD  + W  NG  +    +++  
Sbjct: 1361 VKLVSELTPLTVH--------EGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQVEMA 1409

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRA 3226
             +    +L +   Q  D+G    RA
Sbjct: 1410 QNGSSRILTLRGCQLGDAGTVTLRA 1434



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 96/397 (24%), Positives = 144/397 (36%), Gaps = 57/397 (14%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            S P F++    P  V  G    L+C +  +G+P   V W   G+ +    R     D   
Sbjct: 10   SPPCFLR-FPRPVRVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAE 66

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDA 1294
              L +  A   D G Y  RA N  G A+ +A V V+E     +D +          L+ A
Sbjct: 67   HGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPP--ASDPE----------LQPA 114

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
             R             AP F     +   + G  V L CR   + + T+   W  +G  + 
Sbjct: 115  ERPLPSPGSG---EGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLY--WEKDGMALD 169

Query: 1355 ----TGH-RFRPAYEFD----YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                + H   +P    D     +AL +L+    DSGVY C A N  G           A+
Sbjct: 170  EVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGH----------AQ 219

Query: 1406 KDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFE 1465
               +L+   P                  D  +    +       PK+   V EG+H  F 
Sbjct: 220  AGALLQVHQPP------------ESPPADPDEAPAPVVEPLKCAPKTFW-VNEGKHAKFR 266

Query: 1466 CKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNL 1524
            C +    +   ++EW   G+P+    R     D  G   L ++   A+D G+Y C A N 
Sbjct: 267  CYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNS 324

Query: 1525 VGTDEVSCRLTCRS-TTDIVRSTQNEAGLEQ-IQVLE 1559
             G    + +L  +       R  Q+  G E  I VLE
Sbjct: 325  AGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLE 361



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP F +  +  R   G  A+ +  + G P PVV W +    L    + S  +     + 
Sbjct: 10  SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLS--FPADGAEH 67

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            LL+    P D G Y C ARN  GEA  +  +
Sbjct: 68  GLLLTAALPTDAGVYVCRARNAAGEAYAAAAV 99



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 86/360 (23%), Positives = 139/360 (38%), Gaps = 56/360 (15%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            ++V G  A  +  V    +    V W   G+Q+ ++ R+    D     L + +    D+
Sbjct: 22   RVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDA 79

Query: 1114 GVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEIS 1173
            GVY   ARNAAGEA  +A++TV    + D                E +  E         
Sbjct: 80   GVYVCRARNAAGEAYAAAAVTVLEPPASD---------------PELQPAERPLPSPGSG 124

Query: 1174 KSKPVFVQ-PLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS---VTVGSRFKTY 1229
            +  PVF+  P S    V  G  + L CR   + +PT+   W  +G +   V   S F   
Sbjct: 125  EGAPVFLTGPRSQ--WVLRGAEVVLTCRAGGLPEPTL--YWEKDGMALDEVWDSSHFALQ 180

Query: 1230 ---YDFG---FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
                + G    +AL I+ A   D+G Y   A N  G A   A+++V +  +      +E 
Sbjct: 181  PGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEA 240

Query: 1284 AIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMR 1343
                ++ L+  A +T  V E                     G +    C +  +G     
Sbjct: 241  PAPVVEPLK-CAPKTFWVNE---------------------GKHAKFRCYV--MGKPEPE 276

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFD-YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +EW   G+P+    R     + D    L +L    +D G+Y C A N  G+ +++  L V
Sbjct: 277  IEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV 336



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 65/285 (22%), Positives = 117/285 (41%), Gaps = 45/285 (15%)

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLIL 4574
            S T T     V + +L R+D   T        W K+G+KV+ +    +++ DG    LIL
Sbjct: 726  SLTFTTSERVVLTCELSRVDFPAT--------WYKDGQKVE-ESELLVVKMDGRKHRLIL 776

Query: 4575 -EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
             EA  QDSG++EC    + G +            T   P         P  I++P +   
Sbjct: 777  PEAKVQDSGEFEC---RTEGVS-------AFFGVTVQDP---------PVHIVDPREHVF 817

Query: 4634 V--AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            V     + +  +C++  +  P V+WYK  + ++ S +  +        L +    P D G
Sbjct: 818  VHAITSECVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGG 876

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI-KP 4750
            +++CVA +     TV     +T        P+        VY       +  +T ++ +P
Sbjct: 877  EFQCVAGDECAYFTVT----ITDVSSWIVYPSGK------VYVAAVRLERVVLTCELCRP 926

Query: 4751 --TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
               ++W ++G  + E+P   +  E     L++     ED+G + C
Sbjct: 927  WAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLC 971



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 66  PGEPSPPIFEQIF---KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRY 122
           P E   P+ E +    K     +G +AKF   + G P P + W  +  PL+  ++  + Y
Sbjct: 237 PDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMY 295

Query: 123 NEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            ++ G   L +      D G Y C ARN  G+ + +V +
Sbjct: 296 RDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQL 334



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/91 (28%), Positives = 37/91 (40%)

Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545
           +Q   P F+     + V  G    L    +G P P + W+K G  +  +  L    DG  
Sbjct: 7   DQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAE 66

Query: 546 STLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
             L +  A  +DA  Y C A+N AG     A
Sbjct: 67  HGLLLTAALPTDAGVYVCRARNAAGEAYAAA 97



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 29/109 (26%), Positives = 55/109 (50%), Gaps = 5/109 (4%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GFVILEISPTYPEDS 3490
            + EG++A F   +    +P  ++EW+W G+ L    R   + D  G  +L++     +D 
Sbjct: 257  VNEGKHAKFRCYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDR 314

Query: 3491 GEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            G Y+C A N+ G+ ++   + V+  R  +  ++  + +EG    IA LE
Sbjct: 315  GLYVCAARNSAGQTLSAVQLHVKEPR--LRFTRPLQDVEGREHGIAVLE 361



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 77/358 (21%), Positives = 146/358 (40%), Gaps = 49/358 (13%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            WY++   ++ S    +     K  LI+ +  V+DS  F    E           + V++ 
Sbjct: 750  WYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEG----VSAFFGVTVQDP 805

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                   IV P   +    V+  + + V L  +V   +   V W K+G++V+ +    +L
Sbjct: 806  PVH----IVDPREHVF---VHAITSECVMLACEVD-REDAPVRWYKDGQEVE-ESDFVVL 856

Query: 4564 EEDGTYTLLILEA-YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
            E +G +  L+L A  P D G+++CVA    G+  C    V     +     P  K   A 
Sbjct: 857  ENEGPHRRLVLPATQPSDGGEFQCVA----GD-ECAYFTVTITDVSSWIVYPSGKVYVAA 911

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIK-PSKYFQMSRTADEYTL 4680
              +            + +  +C++  +P   V+W K G+++++ P+   Q   T     L
Sbjct: 912  VRL------------ERVVLTCELC-RPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVL 958

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAK---LKVTQPDQADNLPALTPLRDIVVYEGQP 4737
               +   ED G+Y C   + +   TV      +++  P     L A+T L  +V+     
Sbjct: 959  PAVQL--EDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVT-LECVVLM---- 1011

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
                 +++ +  P ++W ++G  + E+    +  +G    L++     ED G F C A
Sbjct: 1012 ----CELSREDAP-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDA 1064



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 10/147 (6%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYK-STHDFSYVSLDITHTYEEDSG 2844
            EG +  F C V    +P  +IEW +  +PL P   R      D  +V L + +   +D G
Sbjct: 259  EGKHAKFRCYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRG 315

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904
            +Y C A NS G   ++  L    +  + F T+  Q   G E      E ++   R   +P
Sbjct: 316  LYVCAARNSAGQTLSAVQLH-VKEPRLRF-TRPLQDVEGREHGIAVLECKVPNSR---IP 370

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHL 2931
               + + + ++P     Q+ EG V  L
Sbjct: 371  TAWFREDQRLLPCRKYEQIEEGTVRRL 397



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 2/103 (1%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D +  PV  P +   P+   + EG  A+F+  + G P P + W   G+ L+   +  +  
Sbjct: 238 DEAPAPVVEP-LKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYR 296

Query: 317 THN-HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             +    L+V   Q  D G Y   A N  G  +++  L V+ P
Sbjct: 297 DRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 339



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 9/159 (5%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C V     P V W+ + +++ +  +  +L NE  +  L++     SD G   CVA +   
Sbjct: 830 CEVDREDAP-VRWYKDGQEVEES-DFVVLENEGPHRRLVLPATQPSDGGEFQCVAGD--- 884

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
           E A+           +V P      + + +   E VVL       P   + W KDG  ++
Sbjct: 885 ECAYFTVTITDVSSWIVYPSGKVYVAAVRL---ERVVLTCELC-RPWAEVRWTKDGEEVV 940

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +P L +  +     L +P  +  D+  Y C   + + S
Sbjct: 941 ESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESAS 979



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/158 (22%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C ++    P V W+ +  ++ +     +L  +     L++      D G   C A + S 
Sbjct: 1012 CELSREDAP-VRWYKDGLEVEES-EALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDS- 1068

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT-PRITWQKDGVPI 531
              AF         E++V P       +L++  G P  +  R    P   ++ W KDG+ +
Sbjct: 1069 --AFFTVTVTAPPERIVHPAA----RSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEV 1122

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
              +  L++  +G   TL +P A+  DA  Y C  ++ A
Sbjct: 1123 EASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEA 1160



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/101 (24%), Positives = 41/101 (40%)

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            +K +  DQ      L   R + V  G  A+ K  +  +  P + W + G  +  +     
Sbjct: 1    MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSF 60

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              +G    LL+      D G + CRA  AAG+   +A + V
Sbjct: 61   PADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV 101



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 53/218 (24%), Positives = 80/218 (36%), Gaps = 12/218 (5%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491
            +R    A  E +     +P   V W   G+ L A  R     D     L ++   P D+G
Sbjct: 21   VRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAG 80

Query: 3492 EYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPE 3551
             Y+CRA N  GEA   A++ V        E Q     E  +    + EG         P 
Sbjct: 81   VYVCRARNAAGEAYAAAAVTVLEPPASDPELQ---PAERPLPSPGSGEG--------APV 129

Query: 3552 AESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND 3611
              +G   ++    ++++L+  +    E  L    D     E + +    L   R +    
Sbjct: 130  FLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED-GP 188

Query: 3612 FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
               + L I      D+G+Y C A N HG A     LQV
Sbjct: 189  GASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV 226



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIFNFGYVSLNIMHLRAED 839
           + EG++A F   +  +  P   +EW+ +GRP+    R  +    + G+V L +++ +A+D
Sbjct: 257 VNEGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKD 313

Query: 840 AGSYTVRAVNKLGEAISTASIRV 862
            G Y   A N  G+ +S   + V
Sbjct: 314 RGLYVCAARNSAGQTLSAVQLHV 336



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 35/129 (27%), Positives = 51/129 (39%), Gaps = 8/129 (6%)

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNV 502
            E     L + +    D+G   C  R+++         NVI  E  V    +E   S L V
Sbjct: 1133 EGPTRTLTLPHAQPEDAGEYVCETRHEA------ITFNVILAEPPVQFLALETTPSPLCV 1186

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              GEPVVL+        P + W  +G P+     L +H +G    L I  A  + A  Y 
Sbjct: 1187 APGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYT 1245

Query: 563  CTAQNVAGS 571
            C +    G+
Sbjct: 1246 CQSGAAPGA 1254



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 37/180 (20%), Positives = 81/180 (45%), Gaps = 16/180 (8%)

Query: 4621 APPEIIEPLKDKI---VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
            +P  I+ P +D++       + +  +C++     P   WYK  + ++ S+   +     +
Sbjct: 714  SPVHILSP-QDRVSLTFTTSERVVLTCELSRVDFPAT-WYKDGQKVEESELLVVKMDGRK 771

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE--G 4735
            + L + EA  +D G+++C    + G   V+A   VT  D   ++  + P   + V+    
Sbjct: 772  HRLILPEAKVQDSGEFEC---RTEG---VSAFFGVTVQDPPVHI--VDPREHVFVHAITS 823

Query: 4736 QPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            +      ++  +  P ++W ++G  + E+    + +EG +  L++  T   D G F C A
Sbjct: 824  ECVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVA 882



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/57 (35%), Positives = 23/57 (40%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH 4166
            PP F+  P  V V  G  A   C V G P P V+W   G  +    R     DG  H
Sbjct: 11   PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEH 67



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            TTPS L ++        C L   + +   V W HNG+P+  G  ++   +    +L I  
Sbjct: 1179 TTPSPLCVAPGEPVVLSCEL---SRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQA 1235

Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                 AGLYTC++    G  ++S  +QV
Sbjct: 1236 AGPAHAGLYTCQSGAAPGAPSLSFTVQV 1263



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            G D +  V LSG   P V W+K+G+RL +  + ++        LRV+  +  D+G Y
Sbjct: 1285 GGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEY 1340



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 2/103 (1%)

Query: 2632 MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691
            M   +G Q +P          ++V G    L+  V     P   + W K G  L    RL
Sbjct: 1    MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPP--VVVWEKGGQQLAASERL 58

Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                D     L + +    D+G+Y C+A N  GEA + A++ +
Sbjct: 59   SFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV 101



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+   + V  + G +   E +   +G+P   + W K GQ + AS R +         
Sbjct: 11  PPCFLRFPRPVRVVSGAEA--ELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 68

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           L + +    D+G Y CRA +A G A   A + V
Sbjct: 69  LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV 101



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 37/125 (29%), Positives = 50/125 (40%), Gaps = 8/125 (6%)

Query: 623 PYIPPGEEDRVYPPPQFIVPLKSVTA---MEGGKIHFETRIEPVGDPTMKIEWLKNGQSI 679
           P  PP + D    P   + PLK       +  GK H + R   +G P  +IEW   G+ +
Sbjct: 230 PESPPADPDEA--PAPVVEPLKCAPKTFWVNEGK-HAKFRCYVMGKPEPEIEWHWEGRPL 286

Query: 680 EASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERT 737
               R      R G   L +L    +D G Y C A ++ G   +   LHV  PR    R 
Sbjct: 287 LPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP 346

Query: 738 SQHPE 742
            Q  E
Sbjct: 347 LQDVE 351



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 17/156 (10%)

Query: 424 TWFINDRQIRDDYNH--------KILVNESG-NHALMITNVTLSDSGVVTCVARNKSGET 474
           TWF+N  +++ +           +  + + G  H L++  V   DSG +   +     ++
Sbjct: 647 TWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDS 706

Query: 475 AFQCRLNVIEKE-QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
           A    L + E    +++P+  +R S L     E VVL         P  TW KDG  +  
Sbjct: 707 A---ALTIQESPVHILSPQ--DRVS-LTFTTSERVVLTCELSRVDFPA-TWYKDGQKVEE 759

Query: 534 NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           +  L +  DG    L +P AK  D+  ++C  + V+
Sbjct: 760 SELLVVKMDGRKHRLILPEAKVQDSGEFECRTEGVS 795



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 36/169 (21%), Positives = 63/169 (37%), Gaps = 13/169 (7%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + EG  A +   + P       + W  NG  +    ++         +L + G +  D+G
Sbjct: 1372 VHEGDDATFRCEVSPPDAD---VTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAG 1428

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
            T + RA    G    S +L      +  +  F   +Q++   ++GQ    E     V   
Sbjct: 1429 TVTLRA----GSTATSARLHV----RETELLFLRRLQDVRA-EEGQDVCLEVETGRVGAA 1479

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
               + W   GQP+ H +R+    D     L I      D G Y C +++
Sbjct: 1480 G-AVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHH 1527



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 56/247 (22%), Positives = 88/247 (35%), Gaps = 19/247 (7%)

Query: 4362 VAKQKQTQKEVVGDKEITRK--ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQP 4419
            +A Q + Q E  G +++ R     S +  E    A    R+    V+         ++ P
Sbjct: 1310 LASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSELTP 1369

Query: 4420 CRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSA 4479
              V E + A F  E    P   + W R    +   P  ++    +  IL +R   + D  
Sbjct: 1370 LTVHEGDDATFRCEVS-PPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGD-- 1426

Query: 4480 VFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG 4539
              A     R G+   SA L V E             F    Q+V    GQ V L+ +   
Sbjct: 1427 --AGTVTLRAGSTATSARLHVRETELL---------FLRRLQDVRAEEGQDVCLEVETGR 1475

Query: 4540 TKPID-VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
                  V W++ G+ +  D R  + ++   + L I      D G Y C + +    AR  
Sbjct: 1476 VGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLARLS 1535

Query: 4599 A--ECVV 4603
               EC V
Sbjct: 1536 VRRECPV 1542



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/75 (30%), Positives = 35/75 (46%)

Query: 788 AHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
           A  E +   + +P   V W K G+ + AS R++   +     L +      DAG Y  RA
Sbjct: 27  AEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRA 86

Query: 848 VNKLGEAISTASIRV 862
            N  GEA + A++ V
Sbjct: 87  RNAAGEAYAAAAVTV 101



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 5/85 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKL--TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P+ +IEW++ G+ L    R  +    D GFV L ++    +D G+Y C A N  G+  T 
Sbjct: 273  PEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQ--TL 329

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLE 3023
            S V    K+  +  T+  +  EG E
Sbjct: 330  SAVQLHVKEPRLRFTRPLQDVEGRE 354



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 3/70 (4%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD-FGYVAMNFGWVYPEDSGE 4045
            E +  KF C +  +G P  ++EW + G+PLL   R     D  G   +   +   +D G 
Sbjct: 259  EGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGL 316

Query: 4046 YLCRATNLYG 4055
            Y+C A N  G
Sbjct: 317  YVCAARNSAG 326



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V   R  FT+PLQ+++  + G  A  +C+   V +  +   WFR ++ +    +  +  +
Sbjct: 336  VKEPRLRFTRPLQDVEGREHG-IAVLECK---VPNSRIPTAWFREDQRLLPCRKYEQIEE 391

Query: 2431 FGYVSMTISHVRDEDEGVYMC 2451
                 + I  ++ +D+G+Y+C
Sbjct: 392  GTVRRLIIHRLKADDDGIYLC 412



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 9/102 (8%)

Query: 1172 ISKSKPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            +S  +P+ V+ +S   P  V EG +    C + P   P   V W  NG  VT G + +  
Sbjct: 1353 VSVEEPLLVKLVSELTPLTVHEGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQVEMA 1409

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             +     L +      D G  T+RA    GS  TSA + V E
Sbjct: 1410 QNGSSRILTLRGCQLGDAGTVTLRA----GSTATSARLHVRE 1447



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            +P   + W   G+ L    R    +D     L L      D+G+Y C+A N  GEA+ ++
Sbjct: 38   EPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAA 97

Query: 3000 TV 3001
             V
Sbjct: 98   AV 99



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1185 NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244
            +P  V+ G+ + L C L   G P   V W HNGR V  G   + + +     L I  A  
Sbjct: 1182 SPLCVAPGEPVVLSCELSRAGAP---VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGP 1238

Query: 1245 ADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            A  G YT ++    G+   S  V+V E
Sbjct: 1239 AHAGLYTCQSGAAPGAPSLSFTVQVAE 1265



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 15/48 (31%), Positives = 26/48 (54%)

Query: 1743 RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            +V W ++G+ +EAS+ L    +     L + +  PED+G Y C   +E
Sbjct: 1112 QVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHE 1159



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 8/96 (8%)

Query: 1845 RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAAL 1904
            + +++L  P  + EG  A + C + P   P+  V W  NG V+  G +   + +     L
Sbjct: 1362 KLVSELT-PLTVHEGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQVEMAQNGSSRIL 1417

Query: 1905 DILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             +      D+G  T +A    G   +S RL+V+  E
Sbjct: 1418 TLRGCQLGDAGTVTLRA----GSTATSARLHVRETE 1449



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQA 1387
            V L C + P G Q   V W+ +G  ++     +   E     L L    PED+G Y C+ 
Sbjct: 1100 VELRCEVAPAGSQ---VRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCET 1156

Query: 1388 TNQ 1390
             ++
Sbjct: 1157 RHE 1159



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
            +F   ++D+R  E Q    E     VG     V W+R G P+   +RL+   D     L 
Sbjct: 1451 LFLRRLQDVRAEEGQDVCLEVETGRVGAAGA-VRWVRGGQPLPHDSRLSMAQDGHIHRLF 1509

Query: 1772 MKYVNPEDSGTYTCRA 1787
            +  V   D GTY C +
Sbjct: 1510 IHGVILADQGTYGCES 1525



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 3/81 (3%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V  G PV L   L+    P   V W  NGRPVQ+G   +   +     L I  A     G
Sbjct: 1186 VAPGEPVVLSCELSRAGAP---VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAG 1242

Query: 2049 TYMCKATNAVGEAVTTSSVKV 2069
             Y C++  A G    + +V+V
Sbjct: 1243 LYTCQSGAAPGAPSLSFTVQV 1263



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            + EG DA F+ ++S  P   VTW +NG  +    + E+    +   L +R  Q  D+G  
Sbjct: 1372 VHEGDDATFRCEVSP-PDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTV 1430

Query: 337  TLLA 340
            TL A
Sbjct: 1431 TLRA 1434



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 2/98 (2%)

Query: 3828 TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887
            +PP F+   +   V        +C V  +  P   + W + G+ L +  R     D    
Sbjct: 10   SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPV--VVWEKGGQQLAASERLSFPADGAEH 67

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             L +      D+G Y+CRA N  GE +  A ++  + P
Sbjct: 68   GLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPP 105


>BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein.
          Length = 1044

 Score =  120 bits (290), Expect = 1e-25
 Identities = 117/429 (27%), Positives = 176/429 (41%), Gaps = 39/429 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP F +  +P RV    +A  +    GEP P++ W +    +  S          +  L+
Sbjct: 30   PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 89

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVV-------------EEKRRQGRGGIVPPSF 4516
            +      D+ V+   A N  G A  +A + V             E        G   P F
Sbjct: 90   LTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVF 149

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP--DIRNKILE----EDG--- 4567
                ++  V  G  V L  +  G     +YW K+G  +    D  +  L+    EDG   
Sbjct: 150  LTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGA 209

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            +  L IL A   DSG Y C A N+ G A+  A   V  P       P      AP  ++E
Sbjct: 210  SLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPD----EAPAPVVE 265

Query: 4628 PLK--DKI--VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-YTLRI 4682
            PLK   K   V EG+  +F C ++GKP P ++W+   + + P +   M R  D  + L++
Sbjct: 266  PLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKV 325

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                 +D G Y C A NSAG+   A +L V +P     L    PL+D+   E   A  + 
Sbjct: 326  LYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP----RLRFTRPLQDVEGREHGIAVLEC 381

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            ++ +   PT  W RE   +     ++ I EG    L+I     +D G + C      G+V
Sbjct: 382  KVPNSRIPT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE---MRGRV 437

Query: 4803 ETSAKLVVK 4811
             T A + VK
Sbjct: 438  RTVANVTVK 446



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 90/338 (26%), Positives = 133/338 (39%), Gaps = 34/338 (10%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           SPP   + PR  ++  GA+A+ +  + G P P V W K GQ+L  S +           L
Sbjct: 29  SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 88

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +     +D+G Y   A N  G    +  + V  P  S           D + +  E  +
Sbjct: 89  LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPAS-----------DPELQPAERPL 137

Query: 384 EISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD--DYNHKI 440
                   AP F+   + + V  G      CR  G P P + W  +   + +  D +H  
Sbjct: 138 PSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFA 197

Query: 441 LVN---ESG---NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV--------IEKE 486
           L     E G   + AL I    L DSGV  C ARN  G       L V         + +
Sbjct: 198 LQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPD 257

Query: 487 QVVAPKFVERFS----TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542
           +  AP  VE       T  V EG+        +G P P I W  +G P++P+    ++ D
Sbjct: 258 EAPAP-VVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRD 316

Query: 543 -GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             G   L +   +A D   Y C A+N AG T +  +L+
Sbjct: 317 RDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLH 354



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 75/307 (24%), Positives = 112/307 (36%), Gaps = 31/307 (10%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL--INSNKHEIITTHN---- 319
           P     PR+  +  GA+     +  G P P + W K+G  L  +  + H  +        
Sbjct: 147 PVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDG 206

Query: 320 ---HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
                 LR+   +  DSG Y   A N +G       L V  P ES   D       D   
Sbjct: 207 PGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP------DEAP 260

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
               E ++ + K              V EGK  +F C V G+P PE+ W    R +  D 
Sbjct: 261 APVVEPLKCAPKTFW-----------VNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDR 309

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER 496
              +  +  G   L +      D G+  C ARN +G+T    +L+V E       +F   
Sbjct: 310 RRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRL----RFTRP 365

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
              +  RE    VL  +   +  P   W ++   ++P  +     +G    L I R KA 
Sbjct: 366 LQDVEGREHGIAVLECKVPNSRIP-TAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKAD 424

Query: 557 DAAWYQC 563
           D   Y C
Sbjct: 425 DDGIYLC 431



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 101/459 (22%), Positives = 162/459 (35%), Gaps = 51/459 (11%)

Query: 4370 KEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQAR 4429
            +   G+      +T  E    + + Q  ER +  P      P+F    +   V    +  
Sbjct: 106  RNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVV 165

Query: 4430 FEVEFDGEPLPLIKWYRENFPIK---NSPDFQIHTFSTKS------ILIIRQVFVEDSAV 4480
                  G P P + W ++   +    +S  F +     +        L I    + DS V
Sbjct: 166  LTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGV 225

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRR-------QGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
            +   A N  G A+  A L V +          +    +V P      +   V  G+  + 
Sbjct: 226  YVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEP-LKCAPKTFWVNEGKHAKF 284

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECVAINSA 4592
               V G    ++ W   G+ + PD R  +  + DG + L +L    +D G Y C A NSA
Sbjct: 285  RCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSA 344

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
            G+     +  V  P  +                  PL+D    E       CK+    +P
Sbjct: 345  GQTLSAVQLHVKEPRLR---------------FTRPLQDVEGREHGIAVLECKVPNSRIP 389

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            T  W++ D+ + P + ++         L I     +D+G Y C      GRV   A + V
Sbjct: 390  TA-WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC---EMRGRVRTVANVTV 445

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
              P     LP     R + V EG+ A    + T +     +W R+G    E P       
Sbjct: 446  KGP-ILKRLP-----RKLDVLEGENAVLLVE-TLEAGVEGRWSRDG---EELPVICQSSS 495

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G+   L++     ED G      T + G   T+  L VK
Sbjct: 496  GHMHALVLPGVTREDAG----EVTFSLGNSRTTTLLRVK 530



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 103/376 (27%), Positives = 144/376 (38%), Gaps = 64/376 (17%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F    + +RV     A  E + + +G+P   V W + G  + AS RL+   D     L
Sbjct: 31   PCFLRFPRPVRVVSGAEA--ELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 88

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +    P D+G Y CRA N  GEA  ++ + V    +   E Q                 
Sbjct: 89   LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPA--------------- 133

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTK--LSEGQSAHYECRIEPYPDPNMRVEWYFNG---- 1884
            +R      +   AP F+T   GP    +  G      CR    P+P +   W  +G    
Sbjct: 134  ERPLPSPGSGEGAPVFLT---GPRSQWVLRGAEVVLTCRAGGLPEPTL--YWEKDGMALD 188

Query: 1885 KVLQSGH----RYRTSNDFGFA-ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV-QS 1938
            +V  S H      R  +  G + AL IL     DSG Y C A N  G A +   L V Q 
Sbjct: 189  EVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQP 248

Query: 1939 KESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLE 1998
             ES   D     A                       V +P    P K   V EG   H +
Sbjct: 249  PESPPADPDEAPA----------------------PVVEPLKCAP-KTFWVNEGK--HAK 283

Query: 1999 ATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
                 +  P   +EW+  GRP+    R       D G+V L +LY  A+D G Y+C A N
Sbjct: 284  FRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARN 342

Query: 2057 AVGEAVTTSSVKVDAK 2072
            + G+  T S+V++  K
Sbjct: 343  SAGQ--TLSAVQLHVK 356



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 97/381 (25%), Positives = 143/381 (37%), Gaps = 59/381 (15%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            + G+PP F   P  + +   + A  +C  + + +    V W   G+ L    R+    D 
Sbjct: 26   DQGSPPCFLRFPRPVRVVSGAEAELKC--VVLGEPPPVVVWEKGGQQLAASERLSFPADG 83

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
                L +      DAG+Y C+A N  GEA  +  + V       LEP       +    +
Sbjct: 84   AEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV-------LEPP------ASDPEL 130

Query: 3673 QKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT------ 3726
            Q  E  L               P F    +    V  G  V   CR   + +PT      
Sbjct: 131  QPAERPLPS------PGSGEGAPVFLTGPRSQW-VLRGAEVVLTCRAGGLPEPTLYWEKD 183

Query: 3727 -MRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             M +D   +   FA             +AL I      D+G Y C A N  G A   A  
Sbjct: 184  GMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGA-- 241

Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESE 3845
                   ++   Q P+    +  +       + AP  EP+   P       K+  V E +
Sbjct: 242  -------LLQVHQPPESPPADPDE-------APAPVVEPLKCAP-------KTFWVNEGK 280

Query: 3846 GVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHR--YRTVYDMGFVSLDILYVYAEDSGEY 3902
              +F C V  K +P+  IEW+  G+ LLP   R  YR   D GFV L +LY  A+D G Y
Sbjct: 281  HAKFRCYVMGKPEPE--IEWHWEGRPLLPDRRRLMYRD-RDGGFV-LKVLYCQAKDRGLY 336

Query: 3903 ICRAVNDFGEDFTKATISCKK 3923
            +C A N  G+  +   +  K+
Sbjct: 337  VCAARNSAGQTLSAVQLHVKE 357



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 45/141 (31%), Positives = 62/141 (43%), Gaps = 9/141 (6%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            +PP  +   +   V  G   E  C ++G+P P V W KG + +  S+         E+ L
Sbjct: 29   SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 88

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN--LPALTPLRDIVVYEGQPA 4738
             ++ A P D G Y C A N+AG    AA + V +P  +D    PA  PL      EG P 
Sbjct: 89   LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPV 148

Query: 4739 QFKTQITSKIKPTIQWLREGA 4759
             F T       P  QW+  GA
Sbjct: 149  -FLT------GPRSQWVLRGA 162



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 97/364 (26%), Positives = 139/364 (38%), Gaps = 60/364 (16%)

Query: 2240 SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY 2299
            SPP F+   R    V  G  A  +C V  + +P   + +   G+ L ++ R     D   
Sbjct: 29   SPPCFLRFPR-PVRVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAE 85

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L +   +P DAG Y  +A NA G   +A ++TV               LE        
Sbjct: 86   HGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV---------------LEPPASDPEL 130

Query: 2360 EPFKRPEIPEPVTRQ-RPVF-TQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK 2417
            +P +RP +P P + +  PVF T P      +  G      CR   + +PTL   W ++  
Sbjct: 131  QPAERP-LPSPGSGEGAPVFLTGPRSQW--VLRGAEVVLTCRAGGLPEPTLY--WEKDGM 185

Query: 2418 LIE---DSSRIT----KTHDFGYVSMT--ISHVRDEDEGVYMCRASNLLGEXXXXXXXXX 2468
             ++   DSS       +  D    S+   I   R  D GVY+C A N  G          
Sbjct: 186  ALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHG---------- 235

Query: 2469 XXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528
                       H +    +Q + QP E    +PD E   P+   +   P   W  +  H 
Sbjct: 236  -----------HAQAGALLQ-VHQPPESPPADPD-EAPAPVVEPLKCAPKTFWVNEGKHA 282

Query: 2529 EARVVPVGDPSLRFEWYINGVELKMGSR--FRTTHDFGFVTLDINSVVANDAGLYMCKAI 2586
            + R   +G P    EW+  G  L    R       D GFV L +    A D GLY+C A 
Sbjct: 283  KFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAAR 341

Query: 2587 NRAG 2590
            N AG
Sbjct: 342  NSAG 345



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 116/426 (27%), Positives = 163/426 (38%), Gaps = 62/426 (14%)

Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
            +F +P++   V  G    L+  +  + +P   V W   G+ +    R     D     L 
Sbjct: 35   RFPRPVR---VVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 89

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPK 2098
            +  A   D G Y+C+A NA GEA   ++V V     L     D        EL+  ERP 
Sbjct: 90   LTAALPTDAGVYVCRARNAAGEAYAAAAVTV-----LEPPASDP-------ELQPAERPL 137

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR----- 2153
            P      G  PVFLT   S   L+ G      CR   + +P  T+ W  +G  +      
Sbjct: 138  PSPGSGEGA-PVFLTGPRSQWVLR-GAEVVLTCRAGGLPEP--TLYWEKDGMALDEVWDS 193

Query: 2154 ---AGHRYRTTHDFGY-VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL 2209
               A    R     G  +AL IL     DSG Y+C A N  G A     L+V  H+    
Sbjct: 194  SHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--HQPPES 251

Query: 2210 DTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPV 2269
                P+                 E   P + P +   +   T  V EGK A F C V  +
Sbjct: 252  PPADPD-----------------EAPAPVVEPLKCAPK---TFWVNEGKHAKFRCYV--M 289

Query: 2270 HDPNLRIEFYHNGKALQSAAR--FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCT 2327
              P   IE++  G+ L    R   +   D G+V L + +C  +D G Y   A N+ G   
Sbjct: 290  GKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTL 348

Query: 2328 SAISMTV-TAKGSIISESQRPEGLEK-IRELESAEPFKRPEIPEPVTRQRPVFTQPLQNI 2385
            SA+ + V   +       Q  EG E  I  LE   P  R  IP    R+      P +  
Sbjct: 349  SAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSR--IPTAWFREDQRLL-PCRKY 405

Query: 2386 DNIQEG 2391
            + I+EG
Sbjct: 406  EQIEEG 411



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 85/348 (24%), Positives = 135/348 (38%), Gaps = 39/348 (11%)

Query: 927  AHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRA 986
            A  E +   +G+    V W K G+ + AS R++   +     L + +    DAG Y CRA
Sbjct: 46   AEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRA 105

Query: 987  YNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFL 1046
             NA G+A  +A +T++         + P    ++Q  E         E        PR  
Sbjct: 106  RNAAGEAYAAAAVTVL---------EPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQ 156

Query: 1047 GPLKGTNKIVEGQSAHF-EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDI 1105
              L+G   ++  ++    E  +  + D     E + +        R +       +AL I
Sbjct: 157  WVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED-GPGASLALRI 215

Query: 1106 ASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEP 1165
             + R  DSGVY   ARNA G AQ  A +            +H+         +E+    P
Sbjct: 216  LAARLPDSGVYVCHARNAHGHAQAGALL-----------QVHQPPESPPADPDEA----P 260

Query: 1166 MYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR 1225
               +E +  +   F         V+EGK+    C +  MG P   +EW   GR +    R
Sbjct: 261  APVVEPLKCAPKTFW--------VNEGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRR 310

Query: 1226 FKTY--YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
               Y   D GFV L +++  + D G Y   A N  G   ++  + V E
Sbjct: 311  RLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKE 357



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 89/366 (24%), Positives = 146/366 (39%), Gaps = 58/366 (15%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR-PAYEFDYVA 1369
            P F R    +  V G    L+C +  +G+    V W   G+ +    R   PA   ++  
Sbjct: 31   PCFLRFPRPVRVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 88

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSR 1429
            L L +  P D+GVY C+A N  GEA  + A+ V+         + P+   ++Q  E   R
Sbjct: 89   L-LTAALPTDAGVYVCRARNAAGEAYAAAAVTVL---------EPPASDPELQPAE---R 135

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-- 1487
               +    E     P F+T P+S + V+ G  V   C+   + +  L   W K+G  +  
Sbjct: 136  PLPSPGSGEGA---PVFLTGPRS-QWVLRGAEVVLTCRAGGLPEPTL--YWEKDGMALDE 189

Query: 1488 ---TIGHRFRP--IHD--FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540
               +     +P    D     +AL I+     DSG+Y C A N  G  +    L      
Sbjct: 190  VWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPP 249

Query: 1541 DIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERR 1600
            +   +  +EA    ++ L+                 AP      K   + EG+ A F  R
Sbjct: 250  ESPPADPDEAPAPVVEPLK----------------CAP------KTFWVNEGKHAKF--R 285

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSR--FTETNNFGFVALDIMSCLPEDSGTYTCRAINAL 1658
               +     ++EW+   +PL    R       + GFV L ++ C  +D G Y C A N+ 
Sbjct: 286  CYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSA 344

Query: 1659 GEAVTS 1664
            G+ +++
Sbjct: 345  GQTLSA 350



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 73/339 (21%), Positives = 125/339 (36%), Gaps = 20/339 (5%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            D G PP F   F   V +  G  A  E   +  G+   V+ W   G+ + AS R+     
Sbjct: 26   DQGSPPCFLR-FPRPVRVVSG--AEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPAD 82

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
                 L +     TD+G Y CRA N  G+A  +  +  ++      P      + +    
Sbjct: 83   GAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLE-PPASDPELQPAERPLPSPG 141

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSG 3220
             G+ A       PV     + +W   G  +  + R   + +    +    +A  +  DS 
Sbjct: 142  SGEGA-------PVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSS 194

Query: 3221 EYVC---RAYNKYGEDFT-RATINCYGKGGVYL-ESLQPDSLAKIRELESLQGAQQQTPS 3275
             +     RA +  G     R         GVY+  +      A+   L  +    +  P+
Sbjct: 195  HFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPA 254

Query: 3276 TPSAEPPKFITQIQDVTKLV-EGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334
             P   P   +  ++   K     +  H + R   +  P+ ++EW + G+ L    R   +
Sbjct: 255  DPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMY 314

Query: 3335 HD-FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             D  G  +L +LYC  ++ G Y C A N  G+  +   L
Sbjct: 315  RDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQL 353



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 15/147 (10%)

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQN--IEGLK- 3162
            + L IL  +  DSG Y C A N  G A+    L+ V +     P          +E LK 
Sbjct: 211  LALRILAARLPDSGVYVCHARNAHGHAQAGALLQ-VHQPPESPPADPDEAPAPVVEPLKC 269

Query: 3163 --------DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAY 3213
                    +G+ A F C V+   +P+  IEW+  G+P+    R     D  G  VL + Y
Sbjct: 270  APKTFWVNEGKHAKFRCYVMGKPEPE--IEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLY 327

Query: 3214 TQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             Q  D G YVC A N  G+  +   ++
Sbjct: 328  CQAKDRGLYVCAARNSAGQTLSAVQLH 354



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 89/365 (24%), Positives = 138/365 (37%), Gaps = 57/365 (15%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G  P FL     +  +  G  A  +C V  + +P   + W   GQ++ A  R     D  
Sbjct: 28   GSPPCFLRFPRPVR-VVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGA 84

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225
               L +      D+G Y+C+A N  GEA     + V     +      P      R L +
Sbjct: 85   EHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV-----LEPPASDPELQPAERPLPS 139

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
             G              P F+T  R +  V  G      C+   + +P L  E   +G AL
Sbjct: 140  PGSGE---------GAPVFLTGPR-SQWVLRGAEVVLTCRAGGLPEPTLYWE--KDGMAL 187

Query: 2286 QSA-ARFHITFDFGY--------VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
                   H     G         ++L I      D+G Y   A NA GH  +        
Sbjct: 188  DEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQA-------- 239

Query: 2337 KGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHF 2396
             G+++   Q PE          A+P    E P PV    P+   P      + EG+ A F
Sbjct: 240  -GALLQVHQPPES-------PPADP---DEAPAPVVE--PLKCAP--KTFWVNEGKHAKF 284

Query: 2397 DCRLIPVGDPTLKVEW-FRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
             C ++  G P  ++EW +    L+ D  R+  +  D G+V + + + + +D G+Y+C A 
Sbjct: 285  RCYVM--GKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAAR 341

Query: 2455 NLLGE 2459
            N  G+
Sbjct: 342  NSAGQ 346



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 83/364 (22%), Positives = 127/364 (34%), Gaps = 42/364 (11%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F+  P+ +  V+ G     +C +  + +    V W K GQ +    R     D     
Sbjct: 31   PCFLRFPRPVR-VVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 87

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L +   +  D+G+Y CRA N  G    +  +T           +  A   ++Q  E    
Sbjct: 88   LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV---------LEPPASDPELQPAERPLP 138

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHF--ERRLIPVSDA-TLKVEWYHNNKPL 1620
               +     V    P     L+  E+    RA    E  L    D   L   W  ++  L
Sbjct: 139  SPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFAL 198

Query: 1621 KSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQ 1680
            + G    E      +AL I++    DSG Y C A NA G A    +  VH          
Sbjct: 199  QPGR--AEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP 256

Query: 1681 HEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDP 1740
             E   P +  L+   K                F +         N+  H + R   +G P
Sbjct: 257  DEAPAPVVEPLKCAPK---------------TFWV---------NEGKHAKFRCYVMGKP 292

Query: 1741 KLRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799
            +  +EW   G P+    R     D  G   L + Y   +D G Y C A N  G+ +++  
Sbjct: 293  EPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQ 352

Query: 1800 LFVQ 1803
            L V+
Sbjct: 353  LHVK 356



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 13/167 (7%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF--GMVVLEILGTKTTD 3117
            ++EG+ A +   ++  G     IEW + G+ +    R R +Y    G  VL++L  +  D
Sbjct: 276  VNEGKHAKFRCYVM--GKPEPEIEWHWEGRPLLPDRR-RLMYRDRDGGFVLKVLYCQAKD 332

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             G Y C A N  GQ   +V+L      K  + RFT  +Q++EG + G  A  EC    V 
Sbjct: 333  RGLYVCAARNSAGQTLSAVQLHV----KEPRLRFTRPLQDVEGREHG-IAVLEC---KVP 384

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +  +   W+   Q +    + + + +     L I   +  D G Y+C
Sbjct: 385  NSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC 431



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 96/397 (24%), Positives = 144/397 (36%), Gaps = 57/397 (14%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            S P F++    P  V  G    L+C +  +G+P   V W   G+ +    R     D   
Sbjct: 29   SPPCFLR-FPRPVRVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAE 85

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDA 1294
              L +  A   D G Y  RA N  G A+ +A V V+E     +D +          L+ A
Sbjct: 86   HGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPP--ASDPE----------LQPA 133

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
             R             AP F     +   + G  V L CR   + + T+   W  +G  + 
Sbjct: 134  ERPLPSPGSG---EGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLY--WEKDGMALD 188

Query: 1355 ----TGH-RFRPAYEFD----YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                + H   +P    D     +AL +L+    DSGVY C A N  G           A+
Sbjct: 189  EVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGH----------AQ 238

Query: 1406 KDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFE 1465
               +L+   P                  D  +    +       PK+   V EG+H  F 
Sbjct: 239  AGALLQVHQPP------------ESPPADPDEAPAPVVEPLKCAPKTFW-VNEGKHAKFR 285

Query: 1466 CKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDSGIYTCRAVNL 1524
            C +    +   ++EW   G+P+    R     D  G   L ++   A+D G+Y C A N 
Sbjct: 286  CYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNS 343

Query: 1525 VGTDEVSCRLTCRS-TTDIVRSTQNEAGLEQ-IQVLE 1559
             G    + +L  +       R  Q+  G E  I VLE
Sbjct: 344  AGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLE 380



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP F +  +  R   G  A+ +  + G P PVV W +    L    + S  +     + 
Sbjct: 29  SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLS--FPADGAEH 86

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            LL+    P D G Y C ARN  GEA  +  +
Sbjct: 87  GLLLTAALPTDAGVYVCRARNAAGEAYAAAAV 118



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 86/360 (23%), Positives = 139/360 (38%), Gaps = 56/360 (15%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            ++V G  A  +  V    +    V W   G+Q+ ++ R+    D     L + +    D+
Sbjct: 41   RVVSGAEAELKCVV--LGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDA 98

Query: 1114 GVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEIS 1173
            GVY   ARNAAGEA  +A++TV    + D                E +  E         
Sbjct: 99   GVYVCRARNAAGEAYAAAAVTVLEPPASD---------------PELQPAERPLPSPGSG 143

Query: 1174 KSKPVFVQ-PLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS---VTVGSRFKTY 1229
            +  PVF+  P S    V  G  + L CR   + +PT+   W  +G +   V   S F   
Sbjct: 144  EGAPVFLTGPRSQ--WVLRGAEVVLTCRAGGLPEPTL--YWEKDGMALDEVWDSSHFALQ 199

Query: 1230 ---YDFG---FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
                + G    +AL I+ A   D+G Y   A N  G A   A+++V +  +      +E 
Sbjct: 200  PGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEA 259

Query: 1284 AIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMR 1343
                ++ L+  A +T  V E                     G +    C +  +G     
Sbjct: 260  PAPVVEPLK-CAPKTFWVNE---------------------GKHAKFRCYV--MGKPEPE 295

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFD-YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +EW   G+P+    R     + D    L +L    +D G+Y C A N  G+ +++  L V
Sbjct: 296  IEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV 355



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 65/285 (22%), Positives = 117/285 (41%), Gaps = 45/285 (15%)

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLIL 4574
            S T T     V + +L R+D   T        W K+G+KV+ +    +++ DG    LIL
Sbjct: 744  SLTFTTSERVVLTCELSRVDFPAT--------WYKDGQKVE-ESELLVVKMDGRKHRLIL 794

Query: 4575 -EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
             EA  QDSG++EC    + G +            T   P         P  I++P +   
Sbjct: 795  PEAKVQDSGEFEC---RTEGVS-------AFFGVTVQDP---------PVHIVDPREHVF 835

Query: 4634 V--AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            V     + +  +C++  +  P V+WYK  + ++ S +  +        L +    P D G
Sbjct: 836  VHAITSECVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGG 894

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI-KP 4750
            +++CVA +     TV     +T        P+        VY       +  +T ++ +P
Sbjct: 895  EFQCVAGDECAYFTVT----ITDVSSWIVYPSGK------VYVAAVRLERVVLTCELCRP 944

Query: 4751 --TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
               ++W ++G  + E+P   +  E     L++     ED+G + C
Sbjct: 945  WAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLC 989



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 66  PGEPSPPIFEQIF---KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRY 122
           P E   P+ E +    K     +G +AKF   + G P P + W  +  PL+  ++  + Y
Sbjct: 256 PDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMY 314

Query: 123 NEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            ++ G   L +      D G Y C ARN  G+ + +V +
Sbjct: 315 RDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQL 353



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/91 (28%), Positives = 37/91 (40%)

Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545
           +Q   P F+     + V  G    L    +G P P + W+K G  +  +  L    DG  
Sbjct: 26  DQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAE 85

Query: 546 STLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
             L +  A  +DA  Y C A+N AG     A
Sbjct: 86  HGLLLTAALPTDAGVYVCRARNAAGEAYAAA 116



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 29/109 (26%), Positives = 55/109 (50%), Gaps = 5/109 (4%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GFVILEISPTYPEDS 3490
            + EG++A F   +    +P  ++EW+W G+ L    R   + D  G  +L++     +D 
Sbjct: 276  VNEGKHAKFRCYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDR 333

Query: 3491 GEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            G Y+C A N+ G+ ++   + V+  R  +  ++  + +EG    IA LE
Sbjct: 334  GLYVCAARNSAGQTLSAVQLHVKEPR--LRFTRPLQDVEGREHGIAVLE 380



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 27/104 (25%), Positives = 43/104 (41%)

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
            AA +K +  DQ      L   R + V  G  A+ K  +  +  P + W + G  +  +  
Sbjct: 17   AAAMKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASER 76

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                 +G    LL+      D G + CRA  AAG+   +A + V
Sbjct: 77   LSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV 120



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 10/147 (6%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYK-STHDFSYVSLDITHTYEEDSG 2844
            EG +  F C V    +P  +IEW +  +PL P   R      D  +V L + +   +D G
Sbjct: 278  EGKHAKFRCYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRG 334

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904
            +Y C A NS G   ++  L    +  + F T+  Q   G E      E ++   R   +P
Sbjct: 335  LYVCAARNSAGQTLSAVQLH-VKEPRLRF-TRPLQDVEGREHGIAVLECKVPNSR---IP 389

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHL 2931
               + + + ++P     Q+ EG V  L
Sbjct: 390  TAWFREDQRLLPCRKYEQIEEGTVRRL 416



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 39/168 (23%), Positives = 67/168 (39%), Gaps = 10/168 (5%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C V     P V W+ + +++ +  +  +L NE  +  L++     SD G   CVA +   
Sbjct: 848  CEVDREDAP-VRWYKDGQEVEES-DFVVLENEGPHRRLVLPATQPSDGGEFQCVAGD--- 902

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            E A+           +V P      + + +   E VVL       P   + W KDG  ++
Sbjct: 903  ECAYFTVTITDVSSWIVYPSGKVYVAAVRL---ERVVLTCELC-RPWAEVRWTKDGEEVV 958

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS-TATRARLY 579
             +P L +  +     L +P  +  D+  Y C   + + S T T    Y
Sbjct: 959  ESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTESY 1006



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 2/103 (1%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D +  PV  P +   P+   + EG  A+F+  + G P P + W   G+ L+   +  +  
Sbjct: 257 DEAPAPVVEP-LKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYR 315

Query: 317 THN-HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             +    L+V   Q  D G Y   A N  G  +++  L V+ P
Sbjct: 316 DRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 358



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/180 (21%), Positives = 81/180 (45%), Gaps = 16/180 (8%)

Query: 4621 APPEIIEPLKDKI---VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
            +P  I+ P +DK+       + +  +C++     P   WYK  + ++ S+   +     +
Sbjct: 732  SPVHILSP-QDKVSLTFTTSERVVLTCELSRVDFPAT-WYKDGQKVEESELLVVKMDGRK 789

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE--G 4735
            + L + EA  +D G+++C    + G   V+A   VT  D   ++  + P   + V+    
Sbjct: 790  HRLILPEAKVQDSGEFEC---RTEG---VSAFFGVTVQDPPVHI--VDPREHVFVHAITS 841

Query: 4736 QPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            +      ++  +  P ++W ++G  + E+    + +EG +  L++  T   D G F C A
Sbjct: 842  ECVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVA 900



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 53/218 (24%), Positives = 80/218 (36%), Gaps = 12/218 (5%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491
            +R    A  E +     +P   V W   G+ L A  R     D     L ++   P D+G
Sbjct: 40   VRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAG 99

Query: 3492 EYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPE 3551
             Y+CRA N  GEA   A++ V        E Q     E  +    + EG         P 
Sbjct: 100  VYVCRARNAAGEAYAAAAVTVLEPPASDPELQ---PAERPLPSPGSGEG--------APV 148

Query: 3552 AESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND 3611
              +G   ++    ++++L+  +    E  L    D     E + +    L   R +    
Sbjct: 149  FLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED-GP 207

Query: 3612 FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
               + L I      D+G+Y C A N HG A     LQV
Sbjct: 208  GASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV 245



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIFNFGYVSLNIMHLRAED 839
           + EG++A F   +  +  P   +EW+ +GRP+    R  +    + G+V L +++ +A+D
Sbjct: 276 VNEGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKD 332

Query: 840 AGSYTVRAVNKLGEAISTASIRV 862
            G Y   A N  G+ +S   + V
Sbjct: 333 RGLYVCAARNSAGQTLSAVQLHV 355



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/57 (35%), Positives = 23/57 (40%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH 4166
            PP F+  P  V V  G  A   C V G P P V+W   G  +    R     DG  H
Sbjct: 30   PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEH 86



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 2/103 (1%)

Query: 2632 MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691
            M   +G Q +P          ++V G    L+  V     P   + W K G  L    RL
Sbjct: 20   MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPP--VVVWEKGGQQLAASERL 77

Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                D     L + +    D+G+Y C+A N  GEA + A++ +
Sbjct: 78   SFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV 120



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+   + V  + G +   E +   +G+P   + W K GQ + AS R +         
Sbjct: 30  PPCFLRFPRPVRVVSGAEA--ELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 87

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           L + +    D+G Y CRA +A G A   A + V
Sbjct: 88  LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTV 120



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 37/125 (29%), Positives = 50/125 (40%), Gaps = 8/125 (6%)

Query: 623 PYIPPGEEDRVYPPPQFIVPLKSVTA---MEGGKIHFETRIEPVGDPTMKIEWLKNGQSI 679
           P  PP + D    P   + PLK       +  GK H + R   +G P  +IEW   G+ +
Sbjct: 249 PESPPADPDEA--PAPVVEPLKCAPKTFWVNEGK-HAKFRCYVMGKPEPEIEWHWEGRPL 305

Query: 680 EASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERT 737
               R      R G   L +L    +D G Y C A ++ G   +   LHV  PR    R 
Sbjct: 306 LPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP 365

Query: 738 SQHPE 742
            Q  E
Sbjct: 366 LQDVE 370



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/75 (30%), Positives = 35/75 (46%)

Query: 788 AHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
           A  E +   + +P   V W K G+ + AS R++   +     L +      DAG Y  RA
Sbjct: 46  AEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRA 105

Query: 848 VNKLGEAISTASIRV 862
            N  GEA + A++ V
Sbjct: 106 RNAAGEAYAAAAVTV 120



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 17/156 (10%)

Query: 424 TWFINDRQIRDDYNH--------KILVNESG-NHALMITNVTLSDSGVVTCVARNKSGET 474
           TWF+N  +++ +           +  + + G  H L++  V   DSG +   +     ++
Sbjct: 665 TWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDS 724

Query: 475 AFQCRLNVIEKE-QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
           A    L + E    +++P+  ++ S L     E VVL         P  TW KDG  +  
Sbjct: 725 A---ALTIQESPVHILSPQ--DKVS-LTFTTSERVVLTCELSRVDFPA-TWYKDGQKVEE 777

Query: 534 NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           +  L +  DG    L +P AK  D+  ++C  + V+
Sbjct: 778 SELLVVKMDGRKHRLILPEAKVQDSGEFECRTEGVS 813



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 5/85 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKL--TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P+ +IEW++ G+ L    R  +    D GFV L ++    +D G+Y C A N  G+  T 
Sbjct: 292  PEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQ--TL 348

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLE 3023
            S V    K+  +  T+  +  EG E
Sbjct: 349  SAVQLHVKEPRLRFTRPLQDVEGRE 373



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 3/70 (4%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD-FGYVAMNFGWVYPEDSGE 4045
            E +  KF C +  +G P  ++EW + G+PLL   R     D  G   +   +   +D G 
Sbjct: 278  EGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGL 335

Query: 4046 YLCRATNLYG 4055
            Y+C A N  G
Sbjct: 336  YVCAARNSAG 345



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V   R  FT+PLQ+++  + G  A  +C+   V +  +   WFR ++ +    +  +  +
Sbjct: 355  VKEPRLRFTRPLQDVEGREHG-IAVLECK---VPNSRIPTAWFREDQRLLPCRKYEQIEE 410

Query: 2431 FGYVSMTISHVRDEDEGVYMC 2451
                 + I  ++ +D+G+Y+C
Sbjct: 411  GTVRRLIIHRLKADDDGIYLC 431



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            +P   + W   G+ L    R    +D     L L      D+G+Y C+A N  GEA+ ++
Sbjct: 57   EPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAA 116

Query: 3000 TV 3001
             V
Sbjct: 117  AV 118



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 2/98 (2%)

Query: 3828 TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887
            +PP F+   +   V        +C V  +  P   + W + G+ L +  R     D    
Sbjct: 29   SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPV--VVWEKGGQQLAASERLSFPADGAEH 86

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             L +      D+G Y+CRA N  GE +  A ++  + P
Sbjct: 87   GLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPP 124


>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens cDNA
            FLJ31995 fis, clone NT2RP7009236, weakly similar to
            BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
            CORE ).
          Length = 1252

 Score =  118 bits (285), Expect = 4e-25
 Identities = 103/380 (27%), Positives = 153/380 (40%), Gaps = 33/380 (8%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V   E+     E    P P+I W +E   I  SP    HTF     + I +    DS ++
Sbjct: 162  VLAGEEVTLPCEVKSLPPPIITWAKETQLI--SPFSPRHTFLPSGSMKITETRTSDSGMY 219

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    +  L V           VPP      +++ V  GQ V +     GT 
Sbjct: 220  LCVAINIAGNVTQAVKLNVH----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 269

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W K G  +  D  + +   DGT  L I +A P D+G Y CVA N AG    +   
Sbjct: 270  LPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITL 327

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGD 4660
             V  P T +  +P               ++++    Q IEF C   G P PT++W + G 
Sbjct: 328  HVQEPPTVEDLEPPYNTT---------FQERVA--NQRIEFPCPAKGTPKPTIKWLHNGR 376

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            +L    +   +S   D   L I+   P D G+Y CVA N AG       LKV  P    +
Sbjct: 377  EL--TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 434

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
               +T   ++ V   Q      ++     P I W ++   + E+   Q ++ G   +L +
Sbjct: 435  KEQVT---NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGR--ILKL 489

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                 ED G ++C+A   AG
Sbjct: 490  FRATPEDAGRYSCKAINIAG 509



 Score =  112 bits (270), Expect = 3e-23
 Identities = 103/405 (25%), Positives = 158/405 (39%), Gaps = 36/405 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP   +  +  +V   ++        G PLP+I W +    +    D + H  +    L 
Sbjct: 241  PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML--VDGEHHVSNPDGTLS 298

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I Q    D+ ++  VA N  GT +    L V+E        + PP  T   + V   + Q
Sbjct: 299  IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVE--DLEPPYNTTFQERV---ANQ 353

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             +       GT    + WL NG+++        + EDGT  L+I    P D+G+Y CVA+
Sbjct: 354  RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAV 412

Query: 4590 NSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N AG         V +P   KDK               E + +  V   Q     C++ G
Sbjct: 413  NEAGTTERKYNLKVHVPPVIKDK---------------EQVTNVSVLLNQLTNLFCEVEG 457

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + WYK +  +  S   Q         L++  A PED G Y C A N AG      
Sbjct: 458  TPSPIIMWYKDNVQVTESSTIQTVNNGR--ILKLFRATPEDAGRYSCKAINIAGTSQKYF 515

Query: 4709 KLKVTQPDQ--ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETP 4765
             + V  P      N P      ++ V   +    + Q+     P I W ++G  L    P
Sbjct: 516  NIDVLVPPTIIGTNFP-----NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 570

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            + +++  G   VL + N    D G + C  + AAG+     KL +
Sbjct: 571  NVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 613



 Score =  106 bits (255), Expect = 2e-21
 Identities = 92/382 (24%), Positives = 165/382 (43%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P++ W ++  P+K + + +I     K  ++  Q    D   +  VA +  G
Sbjct: 733  ECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAG 790

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWL 4548
              +    + V          +VPP+     +     V    L+ LD  VTG+ P  + WL
Sbjct: 791  EKEIKYEVDV----------LVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWL 840

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ V      KIL       L+I +A   ++G Y C+A N+AG+ + + E  V +P  
Sbjct: 841  KDGQLVDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKEEFEVTVHVP-- 896

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  K++         L +++V + + +   C   G P P++ W K D+ +  ++ 
Sbjct: 897  -----PTIKSSG--------LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ- 942

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
              +   +    L+I++   ED G Y CVA N+AG      +L V +P   ++   +  L 
Sbjct: 943  GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKM--LN 1000

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            + V+    P Q + +      P I W ++  L+  +     ++ G   ++ I +    D 
Sbjct: 1001 ETVLV-SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDA 1057

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A  +AG  E    L V
Sbjct: 1058 GIYKCVAINSAGATELFYSLQV 1079



 Score =  103 bits (248), Expect = 1e-20
 Identities = 102/380 (26%), Positives = 149/380 (39%), Gaps = 35/380 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   I  S   +    +  S+ ++     E+S  +   A N  G AK  
Sbjct: 77   GNPKPSVIWSKKGELISTS-SAKFSAGADGSLYVVSPGG-EESGEYVCTATNTAGYAKRK 134

Query: 4496 ANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V  + R    + G+           ++V +G+ V L  +V    P  + W K  + 
Sbjct: 135  VQLTVYVRPRVFGDQRGLSQDK----PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 190

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P          G+  + I E    DSG Y CVAIN AG      +  V          
Sbjct: 191  ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVAINIAGNVTQAVKLNV---------- 238

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  + PP+I    K   V  GQ ++  C   G PLP + W KG   +       +S 
Sbjct: 239  ------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 292

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRDIV 4731
               + TL I +A P D G Y CVA N AG       L V +P   ++L  P  T  ++ V
Sbjct: 293  P--DGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 350

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                Q  +F        KPTI+WL  G  L    P   ++ +G   +L+I +    D G 
Sbjct: 351  A--NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGE 406

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A   AG  E    L V
Sbjct: 407  YICVAVNEAGTTERKYNLKV 426



 Score =  103 bits (248), Expect = 1e-20
 Identities = 94/376 (25%), Positives = 157/376 (41%), Gaps = 36/376 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++   +     F+I     K  L+I Q  V ++ ++  +A N  G  K  
Sbjct: 831  GSPPPTIMWLKDGQLVDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANTAGDHKEE 888

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + V           VPP+   +  +  V    + V L     G     + WLK+ + V
Sbjct: 889  FEVTVH----------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV 938

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 N  ++  G   L I +   +D+G+Y CVA N+AGE +   +  V  P       P
Sbjct: 939  NTAQGNLKIQSSGR-VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP-------P 990

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              + A         + ++ V     ++  CK  G P+P + WYK ++L+  S    M+  
Sbjct: 991  SLEDAGK-------MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFL 1041

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 + I  A   D G YKCVA NSAG   +   L+V     A ++     +  +VV  
Sbjct: 1042 NRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV---HVAPSISGSNNMVAVVV-- 1096

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
              P + + +      P++ WL++G+ +    +   +  G   +L + +    DTG +TC 
Sbjct: 1097 NNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILALTSAQISDTGRYTCV 1155

Query: 4795 ATTAAGQVETSAKLVV 4810
            A  AAG+ +    L V
Sbjct: 1156 AVNAAGEKQRDIDLRV 1171



 Score =  100 bits (239), Expect = 1e-19
 Identities = 111/431 (25%), Positives = 160/431 (37%), Gaps = 45/431 (10%)

Query: 4378 ITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGE 4437
            +   I  T+ TEI    Q      E P      P +    Q  RV  +++  F     G 
Sbjct: 313  VATNIAGTDETEITLHVQ------EPPTVEDLEPPYNTTFQE-RV-ANQRIEFPCPAKGT 364

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P IKW      +       I      ++L+I  V   D+  +  VA N  GT +   N
Sbjct: 365  PKPTIKWLHNGRELTGREP-GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYN 423

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            L V           VPP      Q  NV+V   QL  L  +V GT    + W K+   VQ
Sbjct: 424  LKVH----------VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN--VQ 471

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                + I   +    L +  A P+D+G+Y C AIN AG ++      V +P       P 
Sbjct: 472  VTESSTIQTVNNGRILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVP-------PT 524

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRT 4674
                N P E+   L   +  E       C++ G P P + W+K G  L       ++   
Sbjct: 525  IIGTNFPNEVSVVLNRDVALE-------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDR 577

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                 L +  A   D+G Y+C   N+AG+     KL +  P         T   DI V  
Sbjct: 578  GQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTT---DISVLI 632

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
                + + +      P I W ++G  I  +     I +G    L I      D+ T+TC 
Sbjct: 633  NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ--YLHIPRAQVSDSATYTCH 690

Query: 4795 ATTAAGQVETS 4805
                AG  E S
Sbjct: 691  VANVAGTAEKS 701



 Score = 98.3 bits (234), Expect = 6e-19
 Identities = 92/352 (26%), Positives = 143/352 (40%), Gaps = 31/352 (8%)

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
            T  +   L I +V ++D   +  VA N  GT   + ++VV           V P+     
Sbjct: 9    TVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH----------VLPTIQHGQ 58

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580
            Q ++   G  V L  K +G     V W K G+ +           DG+  L ++    ++
Sbjct: 59   QILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEE 116

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
            SG+Y C A N+AG A+   +  V +       +P+           +P++  ++A G+ +
Sbjct: 117  SGEYVCTATNTAGYAKRKVQLTVYV-------RPRVFGDQRGLSQDKPVEISVLA-GEEV 168

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT-ADEYTLRISEAFPEDEGDYKCVAYN 4699
               C++   P P + W K  +LI P   F    T     +++I+E    D G Y CVA N
Sbjct: 169  TLPCEVKSLPPPIITWAKETQLISP---FSPRHTFLPSGSMKITETRTSDSGMYLCVAIN 225

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
             AG VT A KL V  P +    P     + + V  GQ             P I W + G+
Sbjct: 226  IAGNVTQAVKLNVHVPPKIQRGP-----KHLKVQVGQRVDIPCNAQGTPLPVITWSKGGS 280

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +    D +      +  L I      D G +TC AT  AG  ET   L V+
Sbjct: 281  TM--LVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQ 330



 Score = 98.3 bits (234), Expect = 6e-19
 Identities = 88/301 (29%), Positives = 127/301 (42%), Gaps = 37/301 (12%)

Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
           EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 65  EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 122

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 123 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 161

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
               V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 162 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 214

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           DSG+  CVA N +G      +LNV      V PK       L V+ G+ V +   A GTP
Sbjct: 215 DSGMYLCVAINIAGNVTQAVKLNVH-----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 269

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            P ITW K G  ++ + E  +    G  TL I +A  SDA  Y C A N+AG+  T   L
Sbjct: 270 LPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITL 327

Query: 579 Y 579
           +
Sbjct: 328 H 328



 Score = 98.3 bits (234), Expect = 6e-19
 Identities = 88/308 (28%), Positives = 130/308 (42%), Gaps = 37/308 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PPKI + P++ K+Q G          G P P +TW K G  ++   +H +  ++   TL 
Sbjct: 241 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLS 298

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +     SD+G YT +A N  G   T   L V                   Q+  T E +E
Sbjct: 299 IDQATPSDAGIYTCVATNIAGTDETEITLHV-------------------QEPPTVEDLE 339

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
                  P +    Q+R     +   F C   G P P + W  N R++       I + E
Sbjct: 340 -------PPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGR-EPGISILE 389

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
            G   L+I +VT  D+G   CVA N++G T  +  L V     V+  K  E+ + ++V  
Sbjct: 390 DGT-LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-HVPPVIKDK--EQVTNVSVLL 445

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            +   L     GTP+P I W KD V +  +    I T      L + RA   DA  Y C 
Sbjct: 446 NQLTNLFCEVEGTPSPIIMWYKDNVQVTESS--TIQTVNNGRILKLFRATPEDAGRYSCK 503

Query: 565 AQNVAGST 572
           A N+AG++
Sbjct: 504 AINIAGTS 511



 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 98/394 (24%), Positives = 157/394 (39%), Gaps = 41/394 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I +  +    V +++    +   +G P P I W +++ P+ N+    +   S+  +L 
Sbjct: 897  PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 955

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS-- 4527
            I +  +ED+  +  VA N  G  +    L V E          PPS     + +N T   
Sbjct: 956  IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHE----------PPSLEDAGKMLNETVLV 1005

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               V+L+ K  G     + W K+ + +        L       + I  A   D+G Y+CV
Sbjct: 1006 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCV 1063

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            AINSAG      E   SL              +  P I        V     +   C+  
Sbjct: 1064 AINSAGAT----ELFYSLQV------------HVAPSISGSNNMVAVVVNNPVRLECEAR 1107

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P P++ W K G  +   S   Q+   +    L ++ A   D G Y CVA N+AG    
Sbjct: 1108 GIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 1165

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L+V  P        +   +++ V   Q  +   Q  +   PT+ WL++G  + + P 
Sbjct: 1166 DIDLRVYVPPNI-----MGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPG 1220

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
              +    N +VL I +   +DTG +TC AT  AG
Sbjct: 1221 LSISE--NRSVLKIEDAQVQDTGRYTCEATNVAG 1252



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 85/382 (22%), Positives = 145/382 (37%), Gaps = 35/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P I W+++  P+    D  +       +L ++     D   +     N  G
Sbjct: 545  ECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 603

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                   L +           +PPS        +++V    L++L+ +  G     + W 
Sbjct: 604  KQAKDIKLTI----------YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY 653

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            K+G+ +    +   +++ G Y L I  A   DS  Y C   N AG A       V +P  
Sbjct: 654  KDGQPIMSSSQALYIDK-GQY-LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVP-- 709

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P  +       +  PL  ++V    ++   CK  G P P + W K    +K +  
Sbjct: 710  -----PMIEG-----NLATPLNKQVVI-AHSLTLECKAAGNPSPILTWLKDGVPVKANDN 758

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             ++   A    L I  A   D G Y CVA + AG   +  ++ V  P   +     +   
Sbjct: 759  IRIE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETS--- 813

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
              +V      +    +T    PTI WL++G L+ E   F+++  G    L+I      +T
Sbjct: 814  YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLVDERDGFKILLNGRK--LVIAQAQVSNT 871

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            G + C A   AG  +   ++ V
Sbjct: 872  GLYRCMAANTAGDHKEEFEVTV 893



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 11/175 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            +R V + K     C   G P P +TW  +D+ +     +  L  +S    L I    L D
Sbjct: 906  ERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN--LKIQSSGRVLQIAKTLLED 963

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN--VREGEPVVLNARAVGT 517
            +G  TCVA N +GET    +L+V E      P   +    LN  V    PV L  +A G 
Sbjct: 964  AGRYTCVATNAAGETQQHIQLHVHE-----PPSLEDAGKMLNETVLVSNPVQLECKAAGN 1018

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P P ITW KD   +  +  +     G    +DI  A+ SDA  Y+C A N AG+T
Sbjct: 1019 PVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGAT 1071



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 64/218 (29%), Positives = 96/218 (44%), Gaps = 15/218 (6%)

Query: 367 RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEV 423
           R QYI        E+ I+     L P  ++   +     V    +   DC VTG P P +
Sbjct: 778 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 837

Query: 424 TWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            W + D Q+ D+ +  KIL+N      L+I    +S++G+  C+A N +G+   +  + V
Sbjct: 838 MW-LKDGQLVDERDGFKILLN---GRKLVIAQAQVSNTGLYRCMAANTAGDHKEEFEVTV 893

Query: 483 IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHT 541
                + +    ER     V + +PV L   A G P P ITW KD  P+      L+I +
Sbjct: 894 HVPPTIKSSGLSERV----VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQS 949

Query: 542 DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            G    L I +    DA  Y C A N AG T    +L+
Sbjct: 950 SG--RVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 985



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 53/161 (32%), Positives = 76/161 (47%), Gaps = 9/161 (5%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R +C   G P P +TW + D      +++ + V  SG   L +T+  +SD+G  TCVA N
Sbjct: 1101 RLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVL-SGGRILALTSAQISDTGRYTCVAVN 1158

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +GE      L V      V P  +     ++V   + V L  ++   P P +TW KDG 
Sbjct: 1159 AAGEKQRDIDLRVY-----VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGH 1213

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P++  P L I  +   S L I  A+  D   Y C A NVAG
Sbjct: 1214 PLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAG 1252



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 15/181 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHAL 450
           P  V V  +RDV        +C+V G P+P++ WF + + +   D N ++L        L
Sbjct: 531 PNEVSVVLNRDVA------LECQVKGTPFPDIHWFKDGKPLFLGDPNVELL---DRGQVL 581

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            + N   +D G   C   N +G+ A   +L +     +         S L       + L
Sbjct: 582 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLI---NSLIKL 638

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P ITW KDG PI+ + +  ++ D G   L IPRA+ SD+A Y C   NVAG
Sbjct: 639 ECETRGLPMPAITWYKDGQPIMSSSQA-LYIDKG-QYLHIPRAQVSDSATYTCHVANVAG 696

Query: 571 S 571
           +
Sbjct: 697 T 697



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 70/281 (24%), Positives = 114/281 (40%), Gaps = 41/281 (14%)

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
            +G P P +TW K+ Q  +N+ +  +    +   L++  T   D+G YT        C+ T
Sbjct: 922  NGIPNPSITWLKDDQP-VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT--------CVAT 972

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            +     +   + +V +  S              +E + K L         +  V      
Sbjct: 973  NAAGETQQHIQLHVHEPPS--------------LEDAGKML---------NETVLVSNPV 1009

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            + +C+  G P P +TW+ ++R +    +   L   +    + I +  +SD+G+  CVA N
Sbjct: 1010 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFL---NRGQIIDIESAQISDAGIYKCVAIN 1066

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
             +G T     L V      VAP      + + V    PV L   A G P P +TW KDG 
Sbjct: 1067 SAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 1121

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P + +    +    G   L +  A+ SD   Y C A N AG
Sbjct: 1122 P-VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 1161



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 13/177 (7%)

Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
           V  D  V    + + +C   G P P +TW+ + + I    + + L  + G + L I    
Sbjct: 624 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS--SSQALYIDKGQY-LHIPRAQ 680

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST-LN--VREGEPVVLNAR 513
           +SDS   TC   N +G       ++V      V P      +T LN  V     + L  +
Sbjct: 681 VSDSATYTCHVANVAGTAEKSFHVDVY-----VPPMIEGNLATPLNKQVVIAHSLTLECK 735

Query: 514 AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           A G P+P +TW KDGVP+  N  +RI  + G   L+I  A+  D   Y C A +VAG
Sbjct: 736 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAG 790



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 338 LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
           L    P   I+  G L V +    Y  D          +  T ER + + K   P  +K 
Sbjct: 378 LTGREPGISILEDGTLLVIASVTPY--DNGEYICVAVNEAGTTER-KYNLKVHVPPVIKD 434

Query: 398 CQ---DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
            +   +  V   ++T   C V G P P + W+ ++ Q+ +    + + N      L +  
Sbjct: 435 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNN---GRILKLFR 491

Query: 455 VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
            T  D+G  +C A N +G +     ++V+    ++   F    S +  R+   V L  + 
Sbjct: 492 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRD---VALECQV 548

Query: 515 VGTPTPRITWQKDGVPII---PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            GTP P I W KDG P+    PN EL    D G   L +  A+ +D   YQCT  N AG 
Sbjct: 549 KGTPFPDIHWFKDGKPLFLGDPNVEL---LDRG-QVLHLKNARRNDKGRYQCTVSNAAGK 604

Query: 572 TATRARL 578
            A   +L
Sbjct: 605 QAKDIKL 611



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           +C+  G P P +TW  +   ++ + N +I   E+G   L I +    D G   CVA + +
Sbjct: 733 ECKAAGNPSPILTWLKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVA 789

Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
           GE   +  ++V+    +      +  S   V     + L+    G+P P I W KDG  +
Sbjct: 790 GEKEIKYEVDVLVPPAIEGG---DETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLV 846

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 +I  +G    L I +A+ S+   Y+C A N AG
Sbjct: 847 DERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAANTAG 883



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 10/179 (5%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G+     C   G P P +TW      +  D  H +  N  G   L I   T SD+G+
Sbjct: 253 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDGT--LSIDQATPSDAGI 309

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            TCVA N +G    +  L+V E   V  + P +   F        + +     A GTP P
Sbjct: 310 YTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA--NQRIEFPCPAKGTPKP 367

Query: 521 RITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            I W  +G  +    P + I  DG  + L I      D   Y C A N AG+T  +  L
Sbjct: 368 TIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 424



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 47/165 (28%), Positives = 67/165 (40%), Gaps = 9/165 (5%)

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER 496
           N  I V   G+  L I  V L D G  TCVA N +G T  +    V+     V P     
Sbjct: 5   NPYITVRSDGS--LHIERVQLQDGGEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHG 57

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
              L+  EG PV L  +A G P P + W K G  +I     +  + G   +L +      
Sbjct: 58  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGE 115

Query: 557 DAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKV 601
           ++  Y CTA N AG    + +L           Q+ L   +P ++
Sbjct: 116 ESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEI 160



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 65/279 (23%), Positives = 101/279 (36%), Gaps = 19/279 (6%)

Query: 71   PPIFEQIFK--NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
            PP  E   K  N         + E K  GNP PV++W +    L      SM +  +   
Sbjct: 989  PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQI 1046

Query: 129  VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH 188
            + +   QI   D G Y C A N  G       +Q                  +    +E 
Sbjct: 1047 IDIESAQIS--DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC 1104

Query: 189  KAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247
            +A G    +    +    V+ ++NG    S           R+L   S + S T RY   
Sbjct: 1105 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG---------RILALTSAQISDTGRYTCV 1155

Query: 248  S-DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
            + +     + D  L    PP I  + +N  +      +   Q    P P +TW K+G  L
Sbjct: 1156 AVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPL 1215

Query: 307  INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            +   K  +  + N + L++ + Q  D+G YT  A N  G
Sbjct: 1216 L--KKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 1252



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 3081 VIEWFYNGKT--IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISV 3136
            VI W   G T  ++  H +          L I     +D+G Y+C ATN  G  + EI++
Sbjct: 272  VITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDETEITL 327

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
             ++     +  +P + T  Q        Q   F C       P +K  W HNG+ +    
Sbjct: 328  HVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK--WLHNGRELTGRE 382

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               ++ + G  +L IA    +D+GEY+C A N+ G
Sbjct: 383  PGISILEDG-TLLVIASVTPYDNGEYICVAVNEAG 416



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLKDG PV + S      + G + L + S  + D G YTC A NA G+     +L +   
Sbjct: 1116 WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 1174

Query: 1005 KDIIAESQH 1013
             +I+ E Q+
Sbjct: 1175 PNIMGEEQN 1183



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 70/270 (25%), Positives = 98/270 (36%), Gaps = 42/270 (15%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     K ++ V  G  V   C  +  G P   I W   G         H  N  G  
Sbjct: 241  PPKIQRGPK-HLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 295

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L ID     DAG YTC ATN  G+  T          +I L  Q P       +++LE 
Sbjct: 296  TLSIDQATPSDAGIYTCVATNIAGTDET----------EITLHVQEP-----PTVEDLE- 339

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
                            P + T  +     +   + F C    K  PK  I+W  NG+ L 
Sbjct: 340  ----------------PPYNTTFQERVANQR--IEFPC--PAKGTPKPTIKWLHNGRELT 379

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
                  ++ + G + L I  V   D+GEYIC AVN+ G    K  +     P I  + QV
Sbjct: 380  GREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 438

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDD 3963
                     LT +   ++   S + +   D
Sbjct: 439  TNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 468



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 29/359 (8%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+  Q  +  C++E  T S + + W+K+   VT     + +++ G + L +     ED+
Sbjct: 442  SVLLNQLTNLFCEVEG-TPSPI-IMWYKDNVQVTESSTIQTVNN-GRI-LKLFRATPEDA 497

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST-QNEAG--LEQIQVLEDRSKYHRTDMVD 1571
            G Y+C+A+N+ GT +    +       I+ +   NE    L +   LE + K      + 
Sbjct: 498  GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 557

Query: 1572 EVTTQAPICTTSLKNVEIKE-GQRAHFE---RRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
                  P+      NVE+ + GQ  H +   R        T+        K +K      
Sbjct: 558  WFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIP 616

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---SGIAIVHSKKSIYLESQHEGA 1684
             +   G V  DI S L        C        A+T    G  I+ S +++Y++      
Sbjct: 617  PSIKGGNVTTDI-SVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH 675

Query: 1685 LPRLNQLEDTSKYQRHSAQ----DEVITQAPVFTMPMKDIRVAE--NQA---AH-FEARL 1734
            +PR  Q+ D++ Y  H A      E      V+  PM +  +A   N+    AH      
Sbjct: 676  IPRA-QVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLEC 734

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
               G+P   + WL++GVP++A++ +    + G   L +      D G Y C A +  GE
Sbjct: 735  KAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGE 791



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 40/167 (23%), Positives = 68/167 (40%), Gaps = 9/167 (5%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S +I W+ +   +  S  I+TV   G + L++      D+G YSC+A N  G ++  
Sbjct: 457  GTPSPIIMWYKDNVQVTESSTIQTVNN-GRI-LKLFRATPEDAGRYSCKAINIAGTSQKY 514

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
              ++ +           T+  N   +   +    EC V     PD  I W+ +G+P+   
Sbjct: 515  FNIDVL----VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLG 568

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                 + D G  VL +   + +D G Y C   N  G+      +  Y
Sbjct: 569  DPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 614



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 3955 SEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGK 4014
            +E+ L   +   V+  +PP + T  Q + +   +E   F C     G P   ++W  NG+
Sbjct: 323  TEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIE---FPCPAK--GTPKPTIKWLHNGR 376

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD 4074
             L  +     I + G + +    V P D+GEY+C A N  G  E K  +K    P I   
Sbjct: 377  ELTGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 435

Query: 4075 SQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             Q+      + ++  +    + TP  ++
Sbjct: 436  EQVTNVSVLLNQLTNLFCEVEGTPSPII 463



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+ +G+ I +S +   +Y      L I   + +DS TY+C   N  G AE S  ++ V
Sbjct: 650  ITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVD-V 706

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                  +    T +   + +    S   EC      +P   + W  +G P++ +  I+  
Sbjct: 707  YVPPMIEGNLATPLN--KQVVIAHSLTLECKA--AGNPSPILTWLKDGVPVKANDNIRI- 761

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             + G   L+I   Q  D G+Y+C A +  GE
Sbjct: 762  -EAGGKKLEIMSAQEIDRGQYICVATSVAGE 791



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T  +  +V + P+    PK ++ V  GQ V   C  +        + W K G  + +   
Sbjct: 231  TQAVKLNVHVPPKIQRGPKHLK-VQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGE 287

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                +  G +++D       D+GIYTC A N+ GTDE    L
Sbjct: 288  HHVSNPDGTLSID--QATPSDAGIYTCVATNIAGTDETEITL 327



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3960 TEDDLYDVDKKQPPRFV-TQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            T    +++D   PP  + T   ++ S+V       ECQ+   G P   + WF +GKPL  
Sbjct: 510  TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKPLFL 567

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             +    + D G V ++       D G Y C  +N  G
Sbjct: 568  GDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAG 603



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     I+W +NG+ +       ++   G  +L I      D+G Y C A N+ G  E  
Sbjct: 363  GTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERK 421

Query: 3134 --ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
              + V +  V K K Q       + N+  L + Q  +  C V     P   I WY +   
Sbjct: 422  YNLKVHVPPVIKDKEQ-------VTNVSVLLN-QLTNLFCEVEGTPSP--IIMWYKDNVQ 471

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  S+ I+TV++    +L +      D+G Y C+A N  G
Sbjct: 472  VTESSTIQTVNNGR--ILKLFRATPEDAGRYSCKAINIAG 509



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ S ++ W  +G  ++A+  IR + A G   LEI+  +  D G Y C AT+  G+ EI 
Sbjct: 738  GNPSPILTWLKDGVPVKANDNIR-IEAGGKK-LEIMSAQEIDRGQYICVATSVAGEKEIK 795

Query: 3136 VKLECVDKSKGQKPRFTTH-IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +++ +     +    T++ I  +  L +      +C V     P   I W  +GQ +  
Sbjct: 796  YEVDVLVPPAIEGGDETSYFIVMVNNLLE-----LDCHV--TGSPPPTIMWLKDGQLVDE 848

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                K + +   +V  IA  Q  ++G Y C A N  G+
Sbjct: 849  RDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGD 884



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   + WLK+G  + + S    +   G I L + S  I D+G YTC AV+A G  
Sbjct: 1105 EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEK 1163

Query: 721  ETKAVLHV 728
            +    L V
Sbjct: 1164 QRDIDLRV 1171



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P   + WYKDG+PI +SS+   I    Y  L+I   +  D+ +YT    N  G A  +  
Sbjct: 646 PMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFH 703

Query: 860 IRVAARSTVTADLGIPEQRRYI 881
           + V     +  +L  P  ++ +
Sbjct: 704 VDVYVPPMIEGNLATPLNKQVV 725



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 17/160 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G+   VI W+ + + +  S  + T    G ++ +I   + +D+G Y C A N  G  E+ 
Sbjct: 1017 GNPVPVITWYKDNRLLSGSTSM-TFLNRGQII-DIESAQISDAGIYKCVAINSAGATELF 1074

Query: 3135 -SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM- 3192
             S+++       G        + N            EC    +  P   + W  +G P+ 
Sbjct: 1075 YSLQVHVAPSISGSNNMVAVVVNN--------PVRLECEARGIPAP--SLTWLKDGSPVS 1124

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              S  ++ +S  G  +L +   Q  D+G Y C A N  GE
Sbjct: 1125 SFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVNAAGE 1162



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   I+WL NG+ +       SI   G + L + S+   D+GEY C AV+  G  E K
Sbjct: 363 GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGTTERK 421

Query: 724 AVL--HVTP 730
             L  HV P
Sbjct: 422 YNLKVHVPP 430



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 40/150 (26%), Positives = 56/150 (37%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I WF +GK +        +   G V L +   +  D G Y C  +N  G+    +KL   
Sbjct: 556  IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 614

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                 +    TT I     +        EC    +  P   I WY +GQP+  S++   +
Sbjct: 615  IPPSIKGGNVTTDI----SVLINSLIKLECETRGLPMP--AITWYKDGQPIMSSSQALYI 668

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             D G   L I   Q  DS  Y C   N  G
Sbjct: 669  -DKG-QYLHIPRAQVSDSATYTCHVANVAG 696



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP  S + + +  V    V LEC  +  G     + W  +G P+ +         
Sbjct: 1077 LQVHVAPSISGSNNMVAVVVNNPVRLECEAR--GIPAPSLTWLKDGSPVSSFSNGLQVLS 1134

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
               + L L S    D+G YTC A N  GE      LRV    +++ E Q+ S L
Sbjct: 1135 GGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL 1187



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 47/174 (27%), Positives = 69/174 (39%), Gaps = 12/174 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            ++I  T+T+DSG Y C A N  G    +VKL      K Q  R   H++    ++ GQ  
Sbjct: 206  MKITETRTSDSGMYLCVAINIAGNVTQAVKLNVHVPPKIQ--RGPKHLK----VQVGQRV 259

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P   I W   G  M         +  G + +D A     D+G Y C A 
Sbjct: 260  DIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS--DAGIYTCVAT 315

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            N  G D T  T++      V  E L+P      +E  + Q  +   P+  + +P
Sbjct: 316  NIAGTDETEITLHVQEPPTV--EDLEPPYNTTFQERVANQRIEFPCPAKGTPKP 367



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
           V+ PP+     K +    G ++      +  G P   I W K G ++            G
Sbjct: 238 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNPDG 295

Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
            +S+D  + +  D+G YTC A +  G  ET+  LHV    T+E
Sbjct: 296 TLSIDQATPS--DAGIYTCVATNIAGTDETEITLHVQEPPTVE 336



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  I W  + + +  +     + + G V L+I  T   D+G Y+C ATN  G+ 
Sbjct: 920  IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGET 978

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            +  ++L   +    +      +    E +        EC      +P   I WY + + +
Sbjct: 979  QQHIQLHVHEPPSLEDAGKMLN----ETVLVSNPVQLECKA--AGNPVPVITWYKDNRLL 1032

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              ST + T  + G  ++DI   Q  D+G Y C A N  G
Sbjct: 1033 SGSTSM-TFLNRG-QIIDIESAQISDAGIYKCVAINSAG 1069



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 17/168 (10%)

Query: 1392 GEAVTSCALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF-- 1446
            GE +++ + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR   
Sbjct: 89   GELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFG 147

Query: 1447 ----VTRPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-G 1500
                +++ K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F  
Sbjct: 148  DQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLP 202

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
              ++ I +    DSG+Y C A+N+ G    + +L       I R  ++
Sbjct: 203  SGSMKITETRTSDSGMYLCVAINIAGNVTQAVKLNVHVPPKIQRGPKH 250



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 62/283 (21%), Positives = 111/283 (39%), Gaps = 22/283 (7%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP  ++  K+ +   G         +G P PV++W++  + ++   ++ +       D +
Sbjct: 241 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV----SNPDGT 296

Query: 131 LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE 187
           L I Q  P D G YTC A N  G  E   ++++Q P                R  ++ +E
Sbjct: 297 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 356

Query: 188 H--KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
               A GT        + T K  + NG + +  +       +  LL   S        Y+
Sbjct: 357 FPCPAKGT-------PKPTIKWLH-NGRELTGREPGISILEDGTLLVIASVTPYDNGEYI 408

Query: 246 GESDVQI-STEIDRSLGPVSPPKIAQKPR--NSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
             +  +  +TE   +L    PP I  K +  N  +          ++ G P P + W+K+
Sbjct: 409 CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD 468

Query: 303 GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             ++  S+   I T +N   L++      D+G Y+  A N  G
Sbjct: 469 NVQVTESS--TIQTVNNGRILKLFRATPEDAGRYSCKAINIAG 509



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   I WLK+ Q +  +     I   G + L +    ++D+G YTC A +A G  +  
Sbjct: 923 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 981

Query: 724 AVLHVTPRATIE 735
             LHV    ++E
Sbjct: 982 IQLHVHEPPSLE 993



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P   + WL++G P+ + SN L  +     +AL    ++  D+G YTC A+N  GE   
Sbjct: 1108 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQIS--DTGRYTCVAVNAAGEKQR 1165

Query: 1797 SSTLFVQSKASLQLESQHESAL 1818
               L V    ++  E Q+ S L
Sbjct: 1166 DIDLRVYVPPNIMGEEQNVSVL 1187



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 77  GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 134

Query: 724 AVL--HVTPR 731
             L  +V PR
Sbjct: 135 VQLTVYVRPR 144



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P+  + WYKD   +T SS I ++ N G + L +     EDAG Y+ +A+N  G +    +
Sbjct: 459 PSPIIMWYKDNVQVTESSTIQTV-NNGRI-LKLFRATPEDAGRYSCKAINIAGTSQKYFN 516

Query: 860 IRVAARSTV 868
           I V    T+
Sbjct: 517 IDVLVPPTI 525



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I  T+  +   +V  + V LE QV+    P+  I WFK+G  L  G       D G V L
Sbjct: 525  IIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRGQV-L 581

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + + R +D G Y C  +N  G+      + I
Sbjct: 582  HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 613



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 39/162 (24%), Positives = 64/162 (39%), Gaps = 18/162 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     I W  +G+ ++     + +     +V  I   + +++G Y C A N  G    
Sbjct: 830  TGSPPPTIMWLKDGQLVDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKE 887

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            + E++V +    KS G   R     + +           +C    + +P   I W  + Q
Sbjct: 888  EFEVTVHVPPTIKSSGLSERVVVKYKPVA---------LQCIANGIPNPS--ITWLKDDQ 936

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+  +     +   G V L IA T   D+G Y C A N  GE
Sbjct: 937  PVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 977



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + + S +   T+ + G + +DI S +  D+G+Y  VA N+AG  +L  S+ V 
Sbjct: 1023 ITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVH 1080

Query: 1137 TRSSIDTSS 1145
               SI  S+
Sbjct: 1081 VAPSISGSN 1089



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 18/270 (6%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           +++  P P+++W  K+  L+  + +S R+       S+ I +    D G Y C A N  G
Sbjct: 173 EVKSLPPPIITWA-KETQLI--SPFSPRHTFLPSG-SMKITETRTSDSGMYLCVAINIAG 228

Query: 154 EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
               +V +                        +   A GT       S+    +   +G 
Sbjct: 229 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGE 287

Query: 214 DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA--QK 271
            H S  D  + + +     +      +     G  + +I+  +        PP +   + 
Sbjct: 288 HHVSNPDGTL-SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE------PPTVEDLEP 340

Query: 272 PRNSKLQEGADAQ---FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
           P N+  QE    Q   F     G P+P + W  NG+ L    +  I    + T L + + 
Sbjct: 341 PYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISILEDGTLLVIASV 399

Query: 329 QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
              D+G Y  +A N  G       L V  P
Sbjct: 400 TPYDNGEYICVAVNEAGTTERKYNLKVHVP 429



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLT 3602
            +D L P    G     T  P+++ +  N     EC++   P  D    + WF +GKPL  
Sbjct: 517  IDVLVPPTIIG-----TNFPNEVSVVLNRDVALECQVKGTPFPD----IHWFKDGKPLFL 567

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            G     + D G  +L +    + D G Y C  +N  G+     KL +
Sbjct: 568  GDPNVELLDRG-QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 613



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 65   EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 120

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 121  VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 150



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 74  KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 129

Query: 154 EA----ICSVYIQP 163
            A      +VY++P
Sbjct: 130 YAKRKVQLTVYVRP 143



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 35/150 (23%), Positives = 60/150 (40%), Gaps = 11/150 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W  +G  + +      V + G + L +   + +D+G Y+C A N  G+ +  + L   
Sbjct: 1114 LTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVY 1172

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                   P      QN+  L   Q+    C    +  P   + W  +G P+     + ++
Sbjct: 1173 -----VPPNIMGEEQNVSVL-ISQAVELLCQSDAIPPP--TLTWLKDGHPLLKKPGL-SI 1223

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            S+    VL I   Q  D+G Y C A N  G
Sbjct: 1224 SE-NRSVLKIEDAQVQDTGRYTCEATNVAG 1252



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E TLH +E  T+ED +P    +    ++ +       + F C  +  G P   I W HNG
Sbjct: 324  EITLHVQEPPTVEDLEPP---YNTTFQERV---ANQRIEFPCPAK--GTPKPTIKWLHNG 375

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            R         ++ + G + L I  +   D GEY C A N+ G+
Sbjct: 376  RELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 417



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 7/103 (6%)

Query: 3271 QQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR 3330
            Q+ P+    EPP + T  Q+    V  Q   F         P +K  W +NG++L     
Sbjct: 330  QEPPTVEDLEPP-YNTTFQE---RVANQRIEFPCPAKGTPKPTIK--WLHNGRELTGREP 383

Query: 3331 YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
              +  + G +++ I      ++GEY CVA N+ G    K NLK
Sbjct: 384  GISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYNLK 425



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 653 KIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCR 712
           K+  ETR    G P   I W K+GQ I +SS+   I +  Y+ +      + DS  YTC 
Sbjct: 637 KLECETR----GLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP--RAQVSDSATYTCH 690

Query: 713 AVSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
             +  G AE    + V     IE     P   Q +
Sbjct: 691 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV 725



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 284 QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
           + + +  G P P +TW+K+GQ +++S++   I    +  L +   Q SDS  YT    N 
Sbjct: 637 KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANV 694

Query: 344 NGCIVTSGYLAVESP 358
            G    S ++ V  P
Sbjct: 695 AGTAEKSFHVDVYVP 709



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WLKD +PV  +       + G V L I    + DAG YTC A NA G+      L +
Sbjct: 929  ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 986



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET- 722
            G+P   I W K+ + +  S+  T + R G I +D+ S  I D+G Y C A+++ G  E  
Sbjct: 1017 GNPVPVITWYKDNRLLSGSTSMTFLNR-GQI-IDIESAQISDAGIYKCVAINSAGATELF 1074

Query: 723  -KAVLHVTP 730
                +HV P
Sbjct: 1075 YSLQVHVAP 1083



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 65   EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 120

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 121  VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 177

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 178  PPPIITWAK 186



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 265 PPKI--AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           PP I     P    +    D   + Q+ G P P + WFK+G+ L   + +  +       
Sbjct: 522 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-V 580

Query: 323 LRVRNTQKSDSGHYTLLAENPNG 345
           L ++N +++D G Y     N  G
Sbjct: 581 LHLKNARRNDKGRYQCTVSNAAG 603



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V + P   +   S   V++ + V  +C    +   N  + W K+ QPV        I  
Sbjct: 892  TVHVPPTIKSSGLSERVVVKYKPVALQCIANGIP--NPSITWLKDDQPVNTAQGNLKIQS 949

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
             G V L I   + ED+G YTC A N  G  +   +L
Sbjct: 950  SGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQL 984



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   V  SS I T  N G + L +   T  DAG Y+C+A N  G +    N+ ++
Sbjct: 463  IMWYKDNVQVTESSTIQTVNN-GRI-LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 520

Query: 1003 TKKDII 1008
                II
Sbjct: 521  VPPTII 526



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+  GQ V +    +    P   I W K G T+        +   G  TLSI+     D+
Sbjct: 252  KVQVGQRVDIPCNAQGTPLP--VITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDA 307

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            GIYTC ATN+ G   +  ++ +++
Sbjct: 308  GIYTCVATNIAGTDETEITLHVQE 331



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+          + G V L +K+   +D G Y C   NA G+      LTI
Sbjct: 556  IHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 613



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFET-RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
           VY PP     L +    +    H  T   +  G+P+  + WLK+G  ++A+         
Sbjct: 706 VYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR--IEA 763

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
           G   L+++S    D G+Y C A S  G  E K  + V     IE
Sbjct: 764 GGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 807



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W KDG P+++ S    + + G + L +   +  D G YT  AVN  GE      
Sbjct: 1110 PAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDID 1168

Query: 860  IRV 862
            +RV
Sbjct: 1169 LRV 1171



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + W KD R +  S+ +T F N G + + I+S  + DAG Y C A N+ G
Sbjct: 1023 ITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAG 1069



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + LEC  E  G P   + W  +G  V+  S        G + L +  A  +DTG YT  A
Sbjct: 1100 VRLEC--EARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVA 1156

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAI--EQIQLL 1291
            VN  G       +RV    +I+ + QN   +  + ++LL
Sbjct: 1157 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 1195



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            K+  GQ     C  +  P P   + W   G  +     +  SN  G  ++D  T    D+
Sbjct: 252  KVQVGQRVDIPCNAQGTPLPV--ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATP--SDA 307

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            G YTC A N  G   + I L+VQ   ++
Sbjct: 308  GIYTCVATNIAGTDETEITLHVQEPPTV 335



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            + TV  S  V+ EC+      P   I WY++ +LL SG    T  + G + +DI      
Sbjct: 1000 NETVLVSNPVQLECKAAGNPVPV--ITWYKDNRLL-SGSTSMTFLNRGQI-IDIESAQIS 1055

Query: 3898 DSGEYICRAVNDFG 3911
            D+G Y C A+N  G
Sbjct: 1056 DAGIYKCVAINSAG 1069



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 15/167 (8%)

Query: 1792 GEAV-TSSTLF-VQSKASLQLESQH-ESALQKIQQLEDSSRYQRREDVEVAVNQAPRFIT 1848
            GE + TSS  F   +  SL + S   E + + +    +++ Y +R+ V++ V   PR   
Sbjct: 89   GELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRK-VQLTVYVRPRVFG 147

Query: 1849 QLNG-----PTKLS--EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
               G     P ++S   G+     C ++  P P   + W    +++       T    G 
Sbjct: 148  DQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLISPFSPRHTFLPSG- 204

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
             ++ I      DSG Y C AIN  G    +++LNV     I R  +H
Sbjct: 205  -SMKITETRTSDSGMYLCVAINIAGNVTQAVKLNVHVPPKIQRGPKH 250



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            N  +E      G P   ++W HNGR +T      +  + G   L I   T  D GEY   
Sbjct: 352  NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICV 410

Query: 1254 AVNHLGSAHTSAIVRV 1269
            AVN  G+      ++V
Sbjct: 411  AVNEAGTTERKYNLKV 426



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  ++WL NG  +       ++ + G + L +  V P D+G Y C A+NE G
Sbjct: 363  GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAG 416



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
            + +Y   D++     I   F   P  + +V+  + V  EC+++     +  + WFK+G+P
Sbjct: 511  SQKYFNIDVLVPPTIIGTNF---PNEV-SVVLNRDVALECQVKGTPFPD--IHWFKDGKP 564

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            + +G     + D G V L + +    D G Y C   N  G      +LT
Sbjct: 565  LFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 612



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRA 3772
            V  +C+V+  G P   I WF +G+P   G     L D G + L +      D G Y C  
Sbjct: 542  VALECQVK--GTPFPDIHWFKDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTV 598

Query: 3773 TNKWGSATTTAKIT 3786
            +N  G      K+T
Sbjct: 599  SNAAGKQAKDIKLT 612



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++  P+  +     +   G V L +     ED+G YTC A N  GE    
Sbjct: 923  GIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQH 981

Query: 1798 STLFVQSKASLQ 1809
              L V    SL+
Sbjct: 982  IQLHVHEPPSLE 993



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            ++ W  + + + +A         G V L IA    ED+G YT VA NAAGE Q    + V
Sbjct: 928  SITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 986

Query: 1136 ETRSSID 1142
                S++
Sbjct: 987  HEPPSLE 993



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/87 (22%), Positives = 39/87 (44%), Gaps = 4/87 (4%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RVY PP  +   ++V+ +    +    + + +  PT+   WLK+G  +      +     
Sbjct: 1170 RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT--WLKDGHPLLKKPGLSISENR 1227

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATG 718
              + ++     +QD+G YTC A +  G
Sbjct: 1228 SVLKIE--DAQVQDTGRYTCEATNVAG 1252



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V    PV  +C+    G+P   I W+ + R   +GS   T  + G I +DI+     
Sbjct: 1000 NETVLVSNPVQLECKA--AGNPVPVITWYKDNR-LLSGSTSMTFLNRGQI-IDIESAQIS 1055

Query: 3764 DAGEYTCRATNKWGS 3778
            DAG Y C A N  G+
Sbjct: 1056 DAGIYKCVAINSAGA 1070



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            T+ +      R  F C  +    P  TI W HNG+++       +  + G + L I    
Sbjct: 344  TTFQERVANQRIEFPCPAK--GTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVT 400

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKV 2201
              D+G Y+C A N+ G       LKV
Sbjct: 401  PYDNGEYICVAVNEAGTTERKYNLKV 426



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   ++W  NG+ L       +  + G  +L I+   P D+GEY+C A N  G      +
Sbjct: 365  PKPTIKWLHNGRELTGREPGISILEDG-TLLVIASVTPYDNGEYICVAVNEAGTTERKYN 423

Query: 3510 MKV 3512
            +KV
Sbjct: 424  LKV 426



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G PS    WY + V++   S  +T ++ G + L +      DAG Y CKAIN AG
Sbjct: 457  GTPSPIIMWYKDNVQVTESSTIQTVNN-GRI-LKLFRATPEDAGRYSCKAINIAG 509



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+P+ +SS+        Y  L I    V D+  YTC   N  G A  S ++ +
Sbjct: 650  ITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 706



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           P   + W KD +P+  +     I + G V L I     EDAG YT  A N  GE
Sbjct: 925 PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE 977



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  +++P+ +     +  + G V L I   L ED+G YTC A NA GE        VH
Sbjct: 929  ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 987

Query: 1671 SKKSI 1675
               S+
Sbjct: 988  EPPSL 992



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W  + +P+ T      I   G V L+I      DAG YTC ATN  GE     +L V
Sbjct: 929  ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 986



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P     WY +   L  GS   T  + G + +DI S   +DAG+Y C AIN AG
Sbjct: 1017 GNPVPVITWYKDN-RLLSGSTSMTFLNRGQI-IDIESAQISDAGIYKCVAINSAG 1069



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 6/109 (5%)

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            T      + V   P        + T+EG  V L C+    G+    V W   G+ I T  
Sbjct: 39   TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKAS--GNPKPSVIWSKKGELISTSS 96

Query: 1358 -RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
             +F    +    +L ++S   E+SG Y C ATN  G A     L V  +
Sbjct: 97   AKFSAGADG---SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 142



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            +L C +E  G P+  + W+ +   VT  S  +T  + G + L +  AT  D G Y+ +A+
Sbjct: 450  NLFCEVE--GTPSPIIMWYKDNVQVTESSTIQTVNN-GRI-LKLFRATPEDAGRYSCKAI 505

Query: 1256 NHLGSAHTSAIVRVIERSDIV-TDTQNEQAI 1285
            N  G++     + V+    I+ T+  NE ++
Sbjct: 506  NIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 536



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   + WYKD R ++ S+ +T   N G + ++I   +  DAG Y   A+N  G      
Sbjct: 1018 NPVPVITWYKDNRLLSGSTSMT-FLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFY 1075

Query: 859  SIRVAARSTVT 869
            S++V    +++
Sbjct: 1076 SLQVHVAPSIS 1086



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 2/47 (4%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            WLKDG P+     ++   N     L I+   V D G YTC A N  G
Sbjct: 1208 WLKDGHPLLKKPGLSISENRS--VLKIEDAQVQDTGRYTCEATNVAG 1252



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)

Query: 695 SLDMLSLNIQDSGEYTCRA--VSATGVAETKAVLHVTPRATIERTSQHPETLQYI 747
           SL +  + +QD GEYTC A  V+ T    T  V+HV P  TI+   Q   T++ I
Sbjct: 15  SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP--TIQHGQQILSTIEGI 67



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 78   NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 134

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 135  VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 189

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 190  LISPFSPRH 198



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 4/98 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V   P+  R   +++   G  V + C  Q  G     + W   G  +        +  
Sbjct: 236  LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDGEHHVSNP 293

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
               +++D  +  P D+G+YTC ATN  G   T   L V
Sbjct: 294  DGTLSIDQAT--PSDAGIYTCVATNIAGTDETEITLHV 329



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + G  +         +  G   L++    P D+G YTC A N  G   T 
Sbjct: 267  GTPLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETE 324

Query: 1798 STLFVQSKASLQ-LESQHESALQK 1820
             TL VQ   +++ LE  + +  Q+
Sbjct: 325  ITLHVQEPPTVEDLEPPYNTTFQE 348



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +E  P P   + WY +   +      +T N+     L +     ED+G Y+CKAIN  
Sbjct: 453  CEVEGTPSPI--IMWYKDNVQVTESSTIQTVNNGRI--LKLFRATPEDAGRYSCKAINIA 508

Query: 1926 GQAVSSIRLNVQSKESII 1943
            G +     ++V    +II
Sbjct: 509  GTSQKYFNIDVLVPPTII 526



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1844 PRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            P  I   N P ++S    +    EC+++  P P+  + W+ +GK L  G       D G 
Sbjct: 522  PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD--IHWFKDGKPLFLGDPNVELLDRG- 578

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L +      D G Y C   N  G+    I+L +    SI
Sbjct: 579  QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI 619



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N +V   H + LE       +P+  + W  +G PV+     +   + G   L+I+ A   
Sbjct: 721  NKQVVIAHSLTLECKAA--GNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEI 776

Query: 2046 DTGTYMCKATNAVGE 2060
            D G Y+C AT+  GE
Sbjct: 777  DRGQYICVATSVAGE 791



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V +  PV L+     + +P+  + W  + +PV            G V L I     ED G
Sbjct: 909  VVKYKPVALQCIANGIPNPS--ITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAG 965

Query: 2049 TYMCKATNAVGE 2060
             Y C ATNA GE
Sbjct: 966  RYTCVATNAAGE 977



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P+ +I W  + Q +            G V L I  T  ED+G Y C ATN  GE      
Sbjct: 925  PNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQ 983

Query: 2199 LKV 2201
            L V
Sbjct: 984  LHV 986



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+F    V  AP  +    +   +V    V LE   E R  P   + W K+G  +++ + 
Sbjct: 1072 ELFYSLQVHVAPSISGS-NNMVAVVVNNPVRLEC--EARGIPAPSLTWLKDGSPVSSFSN 1128

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
                   G + L++ S +  D+G YTC A N  GE      +++     ++GE
Sbjct: 1129 GLQVLSGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGE 1180



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/72 (31%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V   +PV LE     +  P++   W  +G PV            G + L +  A   DTG
Sbjct: 1094 VVVNNPVRLECEARGIPAPSLT--WLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTG 1150

Query: 2049 TYMCKATNAVGE 2060
             Y C A NA GE
Sbjct: 1151 RYTCVAVNAAGE 1162



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITS-ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EAR  P   LT    W  +G  ++S +N +Q     G   L + S +  D+G YT VA N
Sbjct: 1105 EARGIPAPSLT----WLKDGSPVSSFSNGLQVLS--GGRILALTSAQISDTGRYTCVAVN 1158

Query: 1123 AAGEAQLSASMTV 1135
            AAGE Q    + V
Sbjct: 1159 AAGEKQRDIDLRV 1171


>AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein.
          Length = 1040

 Score =  116 bits (280), Expect = 2e-24
 Identities = 99/342 (28%), Positives = 149/342 (43%), Gaps = 45/342 (13%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLL 4572
            P F    QN  V  G  V  D  VTG     V W K+GK ++ D    I E+  G + L+
Sbjct: 697  PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 756

Query: 4573 ILEAYPQDSGKYECVAINSAG------EARCD---------AECVVS---------LPAT 4608
            I    P D G Y C+A NS G      E R D         A+   S         L  +
Sbjct: 757  ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSTS 816

Query: 4609 KDKPKPQTKAANAP-PEIIEPLKDKIVAEGQAI-EFSCKIVGKPLPTVQWYKGDKLIKPS 4666
            +++   ++       P+++E L+D  VA G  + +F  K+ G P P + W+K  + +  S
Sbjct: 817  REQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTAS 876

Query: 4667 KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA--- 4723
             + +M+     +TL I     ED G Y     N+ G    +A+L V  PD+ +  PA   
Sbjct: 877  AHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDV 936

Query: 4724 ---LTPLRDI------VVYEGQPAQFKTQITSKIKPTIQWLREGA------LIPETPDFQ 4768
               L P R +       V +G    F  ++  +  PT+ WLRE A      + P+TP + 
Sbjct: 937  HEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYT 996

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +        L++ +   +  GT+TC A+ AAGQ   SA L V
Sbjct: 997  VASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 1038



 Score =  103 bits (247), Expect = 2e-20
 Identities = 92/343 (26%), Positives = 142/343 (41%), Gaps = 31/343 (9%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--TL 323
            P    + +N ++Q+G    F   ++G P P V WFK+G +L+  + H +I         L
Sbjct: 697  PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDG-KLLEEDDHYMINEDQQGGHQL 755

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY--VQD--QRSQYITD----TQ 375
             +     +D G Y  LAEN  G   T   L V+  +  Y    D  + S Y +     + 
Sbjct: 756  IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLST 815

Query: 376  QRETEERIEISEKALAPQFVKVCQDRDVTEG-KMTRFDCRVTGRPYPEVTWFINDRQIRD 434
             RE E     +++   PQ V+  +D  V  G ++ +F  +V G P P + WF  D Q   
Sbjct: 816  SREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF-KDGQPLT 874

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI------EK--- 485
               H  + ++   H L I +VT  DSG       N  G      RL V       EK   
Sbjct: 875  ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPAS 934

Query: 486  ---EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPII--PNPE 536
               EQ+V P+ +ERF+   V++G  +  + +  G P P + W ++    GV  I    P 
Sbjct: 935  DVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPG 994

Query: 537  LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
              + +     +L +          Y C A N AG     A L+
Sbjct: 995  YTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLH 1037



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 57/208 (27%), Positives = 103/208 (49%), Gaps = 8/208 (3%)

Query: 4514 PSFTLTAQNVNVTSG-QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            P      +++ V  G +L +   KV G     +YW K+G+ +      ++ ++   +TL 
Sbjct: 832  PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 891

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLP-ATKDKPKPQTKAANAPPEIIEPLKD 4631
            I+    +DSG+Y     N+ G A   A  +V  P   ++KP         PP ++E    
Sbjct: 892  IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTP 951

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWY-----KGDKLIKP-SKYFQMSRTADEYTLRISEA 4685
            K V +G +I FS K+ G+P+PTV W      +G   I P +  + ++ +A +++L + + 
Sbjct: 952  KKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDV 1011

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
              + +G Y C+A N+AG+   +A L V+
Sbjct: 1012 GRQHQGTYTCIASNAAGQALCSASLHVS 1039



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 67/230 (29%), Positives = 106/230 (46%), Gaps = 8/230 (3%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT-SIFRFGYIS 695
           P F+  L++    +G  + F+  +   G P   + W K+G+ +E    +  +  + G   
Sbjct: 697 PVFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 754

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT-IERTSQHPETLQYIQQLEDYS 754
           L + ++   D G Y C A ++ GV+ TKA L V   +T  +  +   E+  Y       S
Sbjct: 755 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 814

Query: 755 KYQHQESIEEQT--SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
             + QE  E  T   Q PQ +  L+DL      R A F  QL     P  R+ W+KDG+P
Sbjct: 815 TSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKF--QLKVKGYPAPRLYWFKDGQP 872

Query: 813 ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           +TAS+ I         +L I+ +  ED+G Y     N +G A S+A + V
Sbjct: 873 LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 922



 Score = 88.2 bits (209), Expect = 6e-16
 Identities = 90/365 (24%), Positives = 154/365 (42%), Gaps = 27/365 (7%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYV 1768
            APVF   +++  V +     F+   +  G P   V W ++G  +E  +      D  G  
Sbjct: 696  APVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 753

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS---LQLESQHESALQKIQQLE 1825
             L +  V P D G Y C A N +G + T + L V   ++      ++   S+    Q   
Sbjct: 754  QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 813

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
             +SR Q   +      Q P+ + +L         + A ++ +++ YP P  R+ W+ +G+
Sbjct: 814  STSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYWFKDGQ 871

Query: 1886 VLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
             L +    R ++      L+I++V  EDSG+Y     N +G A SS RL V+  +    +
Sbjct: 872  PLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD----E 927

Query: 1946 SQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVN 2005
             + + A +  + L      +R      F  +K + G  I  +   EG PV     L    
Sbjct: 928  PEEKPASDVHEQLVPPRMLER------FTPKKVKKGSSITFSVKVEGRPVPTVHWLR--E 979

Query: 2006 DPTMRVEWYCNGRPVQQGHRF-KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            +    V W     P   G+    +      V LD+     +  GTY C A+NA G+A+ +
Sbjct: 980  EAERGVLWI---GPDTPGYTVASSAQQHSLVLLDV---GRQHQGTYTCIASNAAGQALCS 1033

Query: 2065 SSVKV 2069
            +S+ V
Sbjct: 1034 ASLHV 1038



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 62/245 (25%), Positives = 106/245 (43%), Gaps = 24/245 (9%)

Query: 244  YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKN 302
            Y+  S  Q  TE     G +  P++ ++ R+ ++  G   A+FQ+++ G P PR+ WFK+
Sbjct: 812  YLSTSREQEGTESTTDEGQL--PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKD 869

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
            GQ L  S    +       TL + +  + DSG Y     N  G   +S  L V  P E  
Sbjct: 870  GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEP- 928

Query: 363  VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
                           E +   ++ E+ + P+ ++    + V +G    F  +V GRP P 
Sbjct: 929  ---------------EEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPT 973

Query: 423  VTWFINDRQ-----IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            V W   + +     I  D     + + +  H+L++ +V     G  TC+A N +G+    
Sbjct: 974  VHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCS 1033

Query: 478  CRLNV 482
              L+V
Sbjct: 1034 ASLHV 1038



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 62/232 (26%), Positives = 96/232 (41%), Gaps = 10/232 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYVA 2036
            P F   ++N EV +G+PV  +  +T    P   V W+ +G+ +++   +    D  G   
Sbjct: 697  PVFLTELQNQEVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 754

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY-- 2094
            L I      D G Y C A N++G + T + ++VD  S  Y    D          + Y  
Sbjct: 755  LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 814

Query: 2095 ---ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
               E+         GQ P  +  L  L+       A F+ +V+    P L   WF +GQ 
Sbjct: 815  TSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLY--WFKDGQP 872

Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
            + A    R T       L+I+    EDSG Y    +N +G A ++  L V G
Sbjct: 873  LTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 924



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 89/369 (24%), Positives = 149/369 (40%), Gaps = 35/369 (9%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-TETNNFGFV 1635
            AP+  T L+N E+++G    F+   +        V W+ + K L+    +    +  G  
Sbjct: 696  APVFLTELQNQEVQDGYPVSFD--CVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 753

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY---LESQHEGALPRLNQLE 1692
             L I + +P D G Y C A N++G + T     V    + Y    ++    +        
Sbjct: 754  QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 813

Query: 1693 DTSKYQRHSAQDEVITQAPVFTMPMKDIRVAE-NQAAHFEARLIPVGDPKLRVEWLRNGV 1751
             TS+ Q  +       Q P     ++D++VA   + A F+ ++   G P  R+ W ++G 
Sbjct: 814  STSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKDGQ 871

Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLE 1811
            P+ AS  +          L +  V  EDSG Y     N +G A +S+ L V+       E
Sbjct: 872  PLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD----E 927

Query: 1812 SQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPY 1871
             + + A    +QL                   PR + +   P K+ +G S  +  ++E  
Sbjct: 928  PEEKPASDVHEQL-----------------VPPRMLERFT-PKKVKKGSSITFSVKVEGR 969

Query: 1872 PDPNMR-VEWYFNGKVLQSG---HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
            P P +  +       VL  G     Y  ++     +L +L V  +  G YTC A N  GQ
Sbjct: 970  PVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 1029

Query: 1928 AVSSIRLNV 1936
            A+ S  L+V
Sbjct: 1030 ALCSASLHV 1038



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 63/234 (26%), Positives = 97/234 (41%), Gaps = 8/234 (3%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S + PVF+  L N   V +G  +  +C +   G P   V WF +G+ +     +    D 
Sbjct: 693  SDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 749

Query: 1233 -GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS---DIVTDTQNEQAIEQI 1288
             G   L I     AD G Y   A N +G + T A +RV   S   D   D     +    
Sbjct: 750  QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 809

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
            Q     +R  +         Q PQ    L +++   GT +  + +L+  G    R+ WF 
Sbjct: 810  QGYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFK 868

Query: 1349 NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +G+P+      R   +     L+++SV  EDSG Y    +N +G A +S  L V
Sbjct: 869  DGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 922



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 34/92 (36%), Positives = 54/92 (58%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP F+   Q+++V +G    FDC VTG+P P V WF + + + +D ++ I  ++ G H L
Sbjct: 696 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 755

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           +IT V  +D GV  C+A N  G ++ +  L V
Sbjct: 756 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 787



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 32/108 (29%), Positives = 60/108 (55%), Gaps = 1/108 (0%)

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
            P    +P P    ++A P  +  L+++ V +G  + F C + G+P+P+V+W+K  KL++ 
Sbjct: 680  PVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEE 739

Query: 4666 SKYFQMSRTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
              ++ ++      + L I+   P D G Y+C+A NS G  +  A+L+V
Sbjct: 740  DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 787



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 59/241 (24%), Positives = 102/241 (42%), Gaps = 10/241 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SL 2833
            VF++ L N   ++G  + F+C V  +  P   + WF + K L     Y    D      L
Sbjct: 698  VFLTELQNQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 755

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDT--QHPQGKAGLEAVEQAE 2891
             IT     D G+Y C A NS G ++T   LR       Y DT     +  +   A     
Sbjct: 756  IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDY-DTAADATESSSYFSAQGYLS 814

Query: 2892 EARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNG 2951
             +R  +G   +  + + P+   ++    + Q+  G  L  + Q++ K  P  ++ W+ +G
Sbjct: 815  TSREQEGTESTTDEGQLPQ---VVEELRDLQVAPGTRL-AKFQLKVKGYPAPRLYWFKDG 870

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011
            + L   +  ++T      TL+++ V   DSG Y     N  G A++S+ +     D   E
Sbjct: 871  QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEE 930

Query: 3012 R 3012
            +
Sbjct: 931  K 931



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 54/190 (28%), Positives = 82/190 (43%), Gaps = 13/190 (6%)

Query: 4428 ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAEN 4487
            A+F+++  G P P + W+++  P+  S   ++        L I  V  EDS  +AA   N
Sbjct: 850  AKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISN 909

Query: 4488 RGGTAKCSANLVV------EEKRRQG-RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
              G A  SA L+V      EEK        +VPP          V  G  +    KV G 
Sbjct: 910  AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR 969

Query: 4541 KPIDVYWLKNGKK-----VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
                V+WL+   +     + PD     +      ++L++L+   Q  G Y C+A N+AG+
Sbjct: 970  PVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 1029

Query: 4595 ARCDAECVVS 4604
            A C A   VS
Sbjct: 1030 ALCSASLHVS 1039



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 105/440 (23%), Positives = 179/440 (40%), Gaps = 55/440 (12%)

Query: 2043 YAEDTGTYMCKATNAVGEA--VTTSSVKVDAKSGLYLDT-LDEQRLKKIQELEKYERPKP 2099
            Y ED   ++C    A+ EA    T   ++ A  G+ ++  L EQ  ++++     E P P
Sbjct: 622  YREDEH-FICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPAP 680

Query: 2100 IEEEQP-------GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
            +   +P          PVFLT L + E +++G    F+C V     P  ++ WF +G+ +
Sbjct: 681  VVPPEPLPSLLTSDAAPVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLL 737

Query: 2153 RAGHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
                 Y    D  G   L I      D G Y C A N +G +     L+V    +   DT
Sbjct: 738  EEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV-DLTSTDYDT 796

Query: 2212 QHPNGLEKIRQLEAQGH-STRIEVEEPKISP-----PRFVTELRGTTHVFEGKTAHFECQ 2265
               +  E      AQG+ ST  E E  + +      P+ V ELR        + A F+ +
Sbjct: 797  A-ADATESSSYFSAQGYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLK 855

Query: 2266 VEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH 2325
            V+    P  R+ ++ +G+ L ++A   +T      +L+I     ED+G+Y+    NA+G 
Sbjct: 856  VKGYPAP--RLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGA 913

Query: 2326 CTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNI 2385
              S+  + V              G ++  E  +++  ++   P  + R  P         
Sbjct: 914  AYSSARLLV-------------RGPDEPEEKPASDVHEQLVPPRMLERFTP--------- 951

Query: 2386 DNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK------LIEDSSRITKTHDFGYVSMTIS 2439
              +++G +  F  ++   G P   V W R E       +  D+   T        S+ + 
Sbjct: 952  KKVKKGSSITFSVKV--EGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLL 1009

Query: 2440 HVRDEDEGVYMCRASNLLGE 2459
             V  + +G Y C ASN  G+
Sbjct: 1010 DVGRQHQGTYTCIASNAAGQ 1029



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 62/235 (26%), Positives = 99/235 (42%), Gaps = 9/235 (3%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTFFN 963
            S   P F T +++Q  +++G    F+  +   G     V W KDG+ +E     +     
Sbjct: 693  SDAAPVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQ 749

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI---VTKKDIIAESQHPGGLEKI 1020
             G   L I +V   D G Y C A N++G ++T A L +    T  D  A++         
Sbjct: 750  QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 809

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            Q     SR  + TE      Q P+ +  L+        + A F+ +V+        + W+
Sbjct: 810  QGYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYP--APRLYWF 867

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             +G+ +T++  I+         L+I SV  EDSG Y     NA G A  SA + V
Sbjct: 868  KDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 922



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 56/241 (23%), Positives = 97/241 (40%), Gaps = 16/241 (6%)

Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGASTL 548
           AP F+       V++G PV  +    G P P + W KDG  +  +    I+ D  G   L
Sbjct: 696 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 755

Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXX 608
            I     +D   Y+C A+N  G ++T+A L                              
Sbjct: 756 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDT---------AADATESSSY 806

Query: 609 XXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKI-HFETRIEPVGDPT 667
                YL             +E ++   PQ +  L+ +    G ++  F+ +++  G P 
Sbjct: 807 FSAQGYLSTSREQEGTESTTDEGQL---PQVVEELRDLQVAPGTRLAKFQLKVK--GYPA 861

Query: 668 MKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLH 727
            ++ W K+GQ + AS+      +    +L+++S+  +DSG+Y     +A G A + A L 
Sbjct: 862 PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLL 921

Query: 728 V 728
           V
Sbjct: 922 V 922



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 92/368 (25%), Positives = 141/368 (38%), Gaps = 28/368 (7%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR-ITSIFNFGYV 828
            P F+  LQ+  E+Q+G    F+  +T    P   V W+KDG+ +      + +    G  
Sbjct: 697  PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 753

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARST-VTADLGIPEQRRYIEKTXXX 887
             L I  +   D G Y   A N +G + + A +RV   ST         E   Y       
Sbjct: 754  QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF---SAQ 810

Query: 888  XXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLK 947
                            +  Q P+    ++D         A F+ +++  G    R+ W K
Sbjct: 811  GYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFK 868

Query: 948  DGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
            DG+P+ AS+ I          L I SVT  D+G Y     NA+G A +SA L +V   D 
Sbjct: 869  DGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL-LVRGPD- 926

Query: 1008 IAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV 1067
              E +     +  + L       + T ++VK      F   ++G        + H+  R 
Sbjct: 927  --EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR----PVPTVHW-LRE 979

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E +      V W   G          +      V LD+     +  G YT +A NAAG+A
Sbjct: 980  EAERG----VLWI--GPDTPGYTVASSAQQHSLVLLDVG---RQHQGTYTCIASNAAGQA 1030

Query: 1128 QLSASMTV 1135
              SAS+ V
Sbjct: 1031 LCSASLHV 1038



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 72/324 (22%), Positives = 126/324 (38%), Gaps = 28/324 (8%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P   + W+ +GK+LE+   + +  D  G   L +  V   D G+Y C A N  G + T +
Sbjct: 724  PMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKA 783

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD 3059
             +         +       +      Q    + R++ G +   D G+ P+     +D+  
Sbjct: 784  ELRVDLTSTDYDTAADATESSSYFSAQGYLSTSREQEGTESTTDEGQLPQVVEELRDLQV 843

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
                ++A ++  +   G  +  + WF +G+ + AS  IR      +  LEI+     DSG
Sbjct: 844  APGTRLAKFQLKV--KGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSG 901

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSK-GQKPRFTTHIQNI----------EGLKDGQSAH 3168
             Y+   +N  G A  S +L      +  +KP    H Q +          + +K G S  
Sbjct: 902  QYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSIT 961

Query: 3169 FECTV----VPV-----DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
            F   V    VP      ++ +  + W   G      T   +      V+LD+   + H  
Sbjct: 962  FSVKVEGRPVPTVHWLREEAERGVLWI--GPDTPGYTVASSAQQHSLVLLDVG--RQH-Q 1016

Query: 3220 GEYVCRAYNKYGEDFTRATINCYG 3243
            G Y C A N  G+    A+++  G
Sbjct: 1017 GTYTCIASNAAGQALCSASLHVSG 1040



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 59/234 (25%), Positives = 95/234 (40%), Gaps = 7/234 (2%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIV 3340
            P F+T++Q+  ++ +G    F+   V    P   V WF +GK L     Y    D  G  
Sbjct: 697  PVFLTELQN-QEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 753

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400
             L I      + G Y C+A N +G  STKA L+     +   D+             Q  
Sbjct: 754  QLIITAVVPADMGVYRCLAENSMGVSSTKAELR-VDLTSTDYDTAADATESSSYFSAQGY 812

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
              +   ++ T    ++G+ P     L +++       A F+ ++     P L   W+ +G
Sbjct: 813  LSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRL--YWFKDG 870

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            + L A +  R         LEI     EDSG+Y     N  G A ++A + V+G
Sbjct: 871  QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 924



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 61/239 (25%), Positives = 103/239 (43%), Gaps = 16/239 (6%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GF 3477
            APVF   L N E +++G    F+  +T    P+  V W+ +GK L+    +    D  G 
Sbjct: 696  APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPS--VRWFKDGKLLEEDDHYMINEDQQGG 752

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIA 3536
              L I+   P D G Y C A N+ G + T A ++V      +  +      + T      
Sbjct: 753  HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-----LTSTDYDTAADATESSSYF 807

Query: 3537 ALEGYSGTV---DTLTPEAESGNPPEFTTTPSDLILSENSS-AHFECRLIPVNDSSMRVE 3592
            + +GY  T    +      + G  P+      DL ++  +  A F+ ++      + R+ 
Sbjct: 808  SAQGYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLY 865

Query: 3593 WFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            WF +G+PL   + ++  +      LEI  V + D+G Y    +N  G A  S +L V+G
Sbjct: 866  WFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 924



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 55/229 (24%), Positives = 97/229 (42%), Gaps = 9/229 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GFI 3753
            P F  E++ N +V +G PV FDC V   G P   + WF +G+            D  G  
Sbjct: 697  PVFLTELQ-NQEVQDGYPVSFDCVV--TGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 753

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS-AKRDIVLESQLPQGMSGEKIKE-L 3811
             L I  +   D G Y C A N  G ++T A++       D    +   +  S    +  L
Sbjct: 754  QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 813

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRF-ECRVEPKEDPKLRIEWYRNGK 3870
               R  +  +        P+ + +++   ++ + G R  + +++ K  P  R+ W+++G+
Sbjct: 814  STSREQEGTESTTDEGQLPQVVEELRD--LQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQ 871

Query: 3871 LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             L +    R        +L+I+ V  EDSG+Y     N  G  ++ A +
Sbjct: 872  PLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL 920



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 84/369 (22%), Positives = 138/369 (37%), Gaps = 36/369 (9%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P F T   +  + +     F+C  +        V WF +GK L          D  G   
Sbjct: 697  PVFLTELQNQEVQDGYPVSFDC--VVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQ 754

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V   D G+Y C A N  G ++   +L+V        +    +   S   S Q   
Sbjct: 755  LIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-LTSTDYDTAADATESSSYFSAQGYL 813

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
             T  ++E      ++   P+   E++D    P      F  +V+  G P  R+ WF +G+
Sbjct: 814  STSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVK--GYPAPRLYWFKDGQ 871

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            P    + +   +      L+I  +   D+G+Y    +N  G+A ++A++           
Sbjct: 872  PLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL----------- 920

Query: 3797 SQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPK 3856
              L +G       E E    SD    E +V  PP+ + +     V++   + F  +VE +
Sbjct: 921  --LVRGPD-----EPEEKPASDV--HEQLV--PPRMLERFTPKKVKKGSSITFSVKVEGR 969

Query: 3857 EDPKLRIEWYR----NGKLL--PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910
              P   + W R     G L   P    Y         SL +L V  +  G Y C A N  
Sbjct: 970  PVP--TVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAA 1027

Query: 3911 GEDFTKATI 3919
            G+    A++
Sbjct: 1028 GQALCSASL 1036



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 86/366 (23%), Positives = 147/366 (40%), Gaps = 31/366 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL-KVEWFKNGQPVTIGHRFRPIHDF-GY 1501
            P F+T  ++ E V +G  V F+C    VT   +  V WFK+G+ +     +    D  G 
Sbjct: 697  PVFLTELQNQE-VQDGYPVSFDCV---VTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 752

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST-TDI---VRSTQNEAGLEQIQV 1557
              L I  ++  D G+Y C A N +G       L    T TD      +T++ +       
Sbjct: 753  HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 812

Query: 1558 LEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR-AHFERRLIPVSDATLKVEWYHN 1616
            L    +   T+   +   Q P     L+++++  G R A F+ ++        ++ W+ +
Sbjct: 813  LSTSREQEGTESTTD-EGQLPQVVEELRDLQVAPGTRLAKFQLKV--KGYPAPRLYWFKD 869

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY 1676
             +PL + +    T+      L+I+S   EDSG Y     NA+G A +S   +V       
Sbjct: 870  GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD--- 926

Query: 1677 LESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIP 1736
             E + + A     QL      +R + +      +  F++ ++   V        EA    
Sbjct: 927  -EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---- 981

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
                +  V W+    P          H     +L +  V  +  GTYTC A N  G+A+ 
Sbjct: 982  ----ERGVLWIGPDTPGYTVASSAQQH-----SLVLLDVGRQHQGTYTCIASNAAGQALC 1032

Query: 1797 SSTLFV 1802
            S++L V
Sbjct: 1033 SASLHV 1038



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 61/233 (26%), Positives = 96/233 (41%), Gaps = 13/233 (5%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-GFV 2566
            P+F   L    E+ +G    ++  V     PS+R  W+ +G  L+    +    D  G  
Sbjct: 697  PVFLTELQN-QEVQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGGH 753

Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIID---QAMRPESWEQIQ--L 2621
             L I +VV  D G+Y C A N  G                 D    A    S+   Q  L
Sbjct: 754  QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 813

Query: 2622 KEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKN 2681
              +   +  E   D G  Q P     L+   ++  G  +  + Q++ +  P  ++ WFK+
Sbjct: 814  STSREQEGTESTTDEG--QLPQVVEELRDL-QVAPGTRL-AKFQLKVKGYPAPRLYWFKD 869

Query: 2682 GVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  LT  A ++ T    L TL I S+  +DSG Y    +N +G A S+A + +
Sbjct: 870  GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 922



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 54/212 (25%), Positives = 88/212 (41%), Gaps = 11/212 (5%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF-GYV 4031
            P F+T++Q+Q  + +     F+C +   G P   V WF +GK L   + +    D  G  
Sbjct: 697  PVFLTELQNQ-EVQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 753

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
             +    V P D G Y C A N  G+  TKA ++        YD+       S       +
Sbjct: 754  QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-LTSTDYDTAADATESS--SYFSAQ 810

Query: 4092 ASWQVTPEQVVEES---KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
                 + EQ   ES   + + P V   L D         A+F  +V G+P PR+ W  +G
Sbjct: 811  GYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDG 870

Query: 4149 NTIVNGSRYKLTYDGMYH-FDIPKTRQYDTGK 4179
              +   +  ++T   + H  +I    + D+G+
Sbjct: 871  QPLTASAHIRMTDKKILHTLEIISVTREDSGQ 902



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 54/229 (23%), Positives = 93/229 (40%), Gaps = 10/229 (4%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFV 3207
            P F T +QN E ++DG    F+C V     P   + W+ +G+ +          D  G  
Sbjct: 697  PVFLTELQNQE-VQDGYPVSFDCVVT--GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 753

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVY---LESLQPDSLAKIRELE 3264
             L I      D G Y C A N  G   T+A +        Y    ++ +  S    +   
Sbjct: 754  QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 813

Query: 3265 SLQGAQQQTPSTPS-AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGK 3323
            S    Q+ T ST    + P+ + +++D+      + A F+ ++     P  ++ WF +G+
Sbjct: 814  STSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAP--RLYWFKDGQ 871

Query: 3324 KLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             L      R      +  L+I+    E+SG+Y    +N +G   + A L
Sbjct: 872  PLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL 920



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 78/369 (21%), Positives = 144/369 (39%), Gaps = 34/369 (9%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GL 2699
            AP+F T L++ + + +G  V  +  V  +  P+++  WFK+G  L          D  G 
Sbjct: 696  APVFLTELQNQE-VQDGYPVSFDCVVTGQPMPSVR--WFKDGKLLEEDDHYMINEDQQGG 752

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE----DRHWLLGESLHPDSLDRIGA 2755
              L I ++   D G+Y C A N +G + + A ++++    D       +         G 
Sbjct: 753  HQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGY 812

Query: 2756 LXXXXXXXXXXXXXXXXXX-VFISHLNNIVCKEGDNI-HFECNVEPSRDPTLKIEWFFNN 2813
            L                     +  L ++    G  +  F+  V+    P  ++ WF + 
Sbjct: 813  LSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGY--PAPRLYWFKDG 870

Query: 2814 KPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYF 2873
            +PL +    + T      +L+I     EDSG Y    +N+ G+A +S  L   G      
Sbjct: 871  QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG------ 924

Query: 2874 DTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEG 2933
                P+ K   +  EQ    R+ +   P     +  K    I  + +   VEG+ +    
Sbjct: 925  -PDEPEEKPASDVHEQLVPPRMLERFTP-----KKVKKGSSITFSVK---VEGRPVPTVH 975

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
             +  + + +  + W     +      + + S     +L L+DV  +  G YTC A N  G
Sbjct: 976  WL--REEAERGVLW-----IGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG 1028

Query: 2994 EAFTSSTVY 3002
            +A  S++++
Sbjct: 1029 QALCSASLH 1037



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 4/147 (2%)

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
            D+ T    + ++++  +   AA +  +VR+++   + P FS    + E   G  + LEC 
Sbjct: 432  DLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECV 491

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTG-HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            +    D  +R  W  +G  +  G H           +L +  +   D+G YTCQ +N+ G
Sbjct: 492  VASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFG 549

Query: 1393 EAVTSCALRVIAKKDLILESQHPSGLE 1419
            + VT  A  V++  +   ES     L+
Sbjct: 550  Q-VTHSACVVVSGSESEAESSSGGELD 575



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 8/101 (7%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL------VECNKYSMRYNE 124
            PP   + F   +  +G +  F  K+ G P P V W R++A         +   Y++  + 
Sbjct: 942  PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 1001

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
            Q    SL++  +G   +G YTC A N  G+A+CS  +   G
Sbjct: 1002 QQH--SLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSG 1040



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P+F    +N     G    F+  + G P P V W  K   L+E + + M   +Q G   L
Sbjct: 697 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWF-KDGKLLEEDDHYMINEDQQGGHQL 755

Query: 132 LIKQIGPGDEGEYTCTARNQYG 153
           +I  + P D G Y C A N  G
Sbjct: 756 IITAVVPADMGVYRCLAENSMG 777



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 10/120 (8%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            AA +GY      +  E +    P F+ T  D       +   EC  +  + + +R  W  
Sbjct: 452  AAFKGYK-----VRKEMKQQEGPMFSHTFGDTEAQVGDALRLEC--VVASKADVRARWLK 504

Query: 3596 NGKPLLTGSR--VKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            +G  L  G    +  + D G   L I G+ + DAG YTC+ +N+ G+ T S  + V G +
Sbjct: 505  DGVELTDGRHHHIDQLGD-GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSE 563



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN------FPIKNSPDFQIHTFS 4463
            PP   ++  P +V +     F V+ +G P+P + W RE       +   ++P + + + +
Sbjct: 942  PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 1001

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +  L++  V  +    +  +A N  G A CSA+L V
Sbjct: 1002 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 1038



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDF 2697
            Q+ P+F+ H     +   G  + LE  V  + D  ++  W K+GV LT G          
Sbjct: 466  QEGPMFS-HTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD 522

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  +L I  L   D+G YTC+ +N  G+   +A + +
Sbjct: 523  GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVV 559



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 5/114 (4%)

Query: 941  LRVEWLKDGRPV-EASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            +R  WLKDG  + +           G  +L I  +   DAG YTC+  N  GQ T SA  
Sbjct: 498  VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSA-C 556

Query: 1000 TIVTKKDIIAESQHPGGLEKIQYLEDASRYSK--RTEEEVKITQKPRFLGPLKG 1051
             +V+  +  AES   G L+   +   A R  +  RT+   +++ +  FL   +G
Sbjct: 557  VVVSGSESEAESSSGGELDD-AFRRAARRLHRLFRTKSPAEVSDEELFLSADEG 609



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 22/82 (26%), Positives = 35/82 (42%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F     D +   G   R +C V  +      W  +  ++ D  +H I     G  +L+
Sbjct: 469 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 528

Query: 452 ITNVTLSDSGVVTCVARNKSGE 473
           IT +  +D+G  TC   NK G+
Sbjct: 529 ITGLDRADAGCYTCQVSNKFGQ 550



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-ILI 4469
            P+F  ++Q   V +     F+    G+P+P ++W+++   ++    + I+        LI
Sbjct: 697  PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 756

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I  V   D  V+  +AEN  G +   A L V+
Sbjct: 757  ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 788



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTL 4571
            P F+ T  +     G  +RL+  V     +   WLK+G ++  D R+  +++  DGT +L
Sbjct: 469  PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT-DGRHHHIDQLGDGTCSL 527

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            LI      D+G Y C   N  G+    A  VVS
Sbjct: 528  LITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 560



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 37/161 (22%), Positives = 53/161 (32%), Gaps = 2/161 (1%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            V PE +     +   PVF++      V++G    F C VTG P P V W  +G  +    
Sbjct: 682  VPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD 741

Query: 4156 RYKLTYD--GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNA 4213
             Y +  D  G +   I      D G    +             L+V     DY       
Sbjct: 742  HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADAT 801

Query: 4214 PRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELK 4254
                Y     Y  T  E E T       Q   V++   +L+
Sbjct: 802  ESSSYFSAQGYLSTSREQEGTESTTDEGQLPQVVEELRDLQ 842



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 11/151 (7%)

Query: 4585 ECVAINSA-GEA-RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL----KDKIVAEGQ 4638
            ECV    A GE  R     V  + A +    PQT     PP+ + P     + + VA G+
Sbjct: 151  ECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGE 210

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC-VA 4697
             +    ++V +    + W+KG + I+P   F++     +  L I     ED+G+Y C +A
Sbjct: 211  DVSLELEVVAEAGEVI-WHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLA 269

Query: 4698 YNS--AGRVTVAAKLKVTQPDQADNLPALTP 4726
              S      T    L     D+A   P+L P
Sbjct: 270  QGSICPAAATFQVALSPASVDEAPQ-PSLPP 299



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 4/106 (3%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG-HRYRT 1895
            E+   + P F +   G T+   G +   EC +    D  +R  W  +G  L  G H +  
Sbjct: 462  EMKQQEGPMF-SHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHID 518

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
                G  +L I  +   D+G YTC+  N  GQ   S  + V   ES
Sbjct: 519  QLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSES 564



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            K  ++  E ++   P F+    D  +   G  +  +C V    D  +R  W  +G     
Sbjct: 455  KGYKVRKEMKQQEGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVELTD 511

Query: 3741 GSRVHT--LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            G   H   L D G  +L I  +   DAG YTC+ +NK+G  T +A +  S
Sbjct: 512  GRHHHIDQLGD-GTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 560



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS--NRLTTMHDFG 1766
            + P+F+    D       A   E  +    D  +R  WL++GV +     + +  + D G
Sbjct: 467  EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGD-G 523

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
              +L +  ++  D+G YTC+  N+ G+ VT S   V S +  + ES
Sbjct: 524  TCSLLITGLDRADAGCYTCQVSNKFGQ-VTHSACVVVSGSESEAES 568



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 6/112 (5%)

Query: 753 YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
           +  Y+ ++ +++Q  + P F     D  E Q G     E  +   +D  +R  W KDG  
Sbjct: 454 FKGYKVRKEMKQQ--EGPMFSHTFGDT-EAQVGDALRLECVVASKAD--VRARWLKDGVE 508

Query: 813 IT-ASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
           +T            G  SL I  L   DAG YT +  NK G+   +A + V+
Sbjct: 509 LTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS 560



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 10/137 (7%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYDFGY 2034
            E P F     + E   G  + LE  +    D  +R  W  +G  +  G H        G 
Sbjct: 467  EGPMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGT 524

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGE-------AVTTSSVKVDAKSGLYLDTLDEQRLKK 2087
             +L I      D G Y C+ +N  G+        V+ S  + ++ SG  LD    +  ++
Sbjct: 525  CSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARR 584

Query: 2088 IQELEKYERPKPIEEEQ 2104
            +  L + + P  + +E+
Sbjct: 585  LHRLFRTKSPAEVSDEE 601



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/105 (24%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            VPP  +   ++  V +G+ V L+ +V      +V W K  +++QP  R +++ + G   +
Sbjct: 194  VPPQPS-APESRQVAAGEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQ-GRQQM 250

Query: 4572 LILEAY-PQDSGKYEC-VAINSAGEARCDAECVVSLPATKDKPKP 4614
            L+++ +  +D G+Y C +A  S   A    +  +S  +  + P+P
Sbjct: 251  LVIKGFTAEDQGEYHCGLAQGSICPAAATFQVALSPASVDEAPQP 295



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG-HRYRTVYDMGFVS 3888
            P F         +  + +R EC V  K D  +R  W ++G  L  G H +      G  S
Sbjct: 469  PMFSHTFGDTEAQVGDALRLECVVASKAD--VRARWLKDGVELTDGRHHHIDQLGDGTCS 526

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L I  +   D+G Y C+  N FG+
Sbjct: 527  LLITGLDRADAGCYTCQVSNKFGQ 550



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/86 (25%), Positives = 43/86 (50%), Gaps = 1/86 (1%)

Query: 4727 LRDIVVYEG-QPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
            LRD+ V  G + A+F+ ++     P + W ++G  +  +   +M  +     L I +   
Sbjct: 838  LRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTR 897

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVK 4811
            ED+G +    + A G   +SA+L+V+
Sbjct: 898  EDSGQYAAYISNAMGAAYSSARLLVR 923



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 8/119 (6%)

Query: 2087 KIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWF 2146
            KIQ   K  + +   ++Q G  P+F       E  + GD    EC V    D  +   W 
Sbjct: 449  KIQAAFKGYKVRKEMKQQEG--PMFSHTFGDTE-AQVGDALRLECVVASKAD--VRARWL 503

Query: 2147 HNGQKIRAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKATNKLGEAVNTCTLKVAG 2203
             +G ++  G R+      G     +L T  +  D+G Y C+ +NK G+  ++  + V+G
Sbjct: 504  KDGVELTDG-RHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSG 561



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTC 4793
            G   + +  + SK     +WL++G  + +     +   G+    LLI      D G +TC
Sbjct: 483  GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 542

Query: 4794 RATTAAGQVETSAKLVV 4810
            + +   GQV  SA +VV
Sbjct: 543  QVSNKFGQVTHSACVVV 559



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 12/102 (11%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI- 694
            PP+ +         +G  I F  ++E  G P   + WL+  +  E    +      GY  
Sbjct: 942  PPRMLERFTPKKVKKGSSITFSVKVE--GRPVPTVHWLR--EEAERGVLWIGPDTPGYTV 997

Query: 695  -------SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
                   SL +L +  Q  G YTC A +A G A   A LHV+
Sbjct: 998  ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVS 1039


>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
          Length = 2673

 Score =  115 bits (276), Expect = 5e-24
 Identities = 114/390 (29%), Positives = 162/390 (41%), Gaps = 42/390 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E+ QA      DG P P I W ++N  + N      +T      LI+  V +EDS  +
Sbjct: 1218 VNENSQAILPCVADGIPTPAINWKKDNVLLANL--LGKYTAEPYGELILENVVLEDSGFY 1275

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
              VA N  G    + +L V           V P+FT    +V++  G+ +RL  K TG  
Sbjct: 1276 TCVANNAAGEDTHTVSLTVH----------VLPTFTELPGDVSLNKGEQLRLSCKATGIP 1325

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               + W  N   +     +     +G   L+I     +DSG Y C A NS G  +     
Sbjct: 1326 LPKLTWTFNNNIIPAHFDSV----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 1381

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V  P       P  K  + P   IEPL       G AI  +C++ G P PT+QW +   
Sbjct: 1382 YVKEP-------PVFKG-DYPSHWIEPLG------GNAI-LNCEVKGDPTPTIQWNRKGV 1426

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             I+ S      R     +L I     ED GDY CVA N AG V  +  L +  P     +
Sbjct: 1427 DIEISHRI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP----I 1479

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              L P+ + V+  G       Q T + +PTI W R+G  I       ++   NN+ L I 
Sbjct: 1480 ITLEPV-ETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL--SNNS-LYIA 1535

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  +EDT  F C A    G V     ++V+
Sbjct: 1536 DAQKEDTSEFECVARNLMGSVLVRVPVIVQ 1565



 Score =  110 bits (265), Expect = 1e-22
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 36/396 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P +   K +   V  +       E  G P P + W +   PIK + +  I     +++ I
Sbjct: 2    PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI-VPGGRTLQI 60

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF----TLTAQNVNV 4525
            IR   V D   +  +A N+ G +K   +L V           VPPS     + +   VNV
Sbjct: 61   IR-AKVSDGGEYTCIAINQAGESKKKFSLTV----------YVPPSIKDHDSESLSVVNV 109

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  V L+ +     P  + W KNG+ +      +IL  DG   L I +A   D+G+Y 
Sbjct: 110  REGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEIL-ADG-QMLHIKKAEVSDTGQYV 167

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C AIN AG    +    V +P + + P+ +         I+E + + +         +C 
Sbjct: 168  CRAINVAGRDDKNFHLNVYVPPSIEGPEREV--------IVETISNPVT-------LTCD 212

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P PT+ W K  K I+ S   ++   +    L+I+ +   D G+Y C+A N  G+  
Sbjct: 213  ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 272

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                L +  P       A  P  D+ V  G+  +          P IQWL++G  I    
Sbjct: 273  KYYFLSIQVPPSVAG--AEIP-SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 329

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              ++    N + L I      DTG +TC AT  AG+
Sbjct: 330  TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 365



 Score =  109 bits (261), Expect = 3e-22
 Identities = 100/368 (27%), Positives = 151/368 (41%), Gaps = 34/368 (9%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P PLI+W ++  PI +    +I   +  S L I      D+  +  VA N  G    
Sbjct: 309  NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR 368

Query: 4495 SANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              NL V      +G         TL   ++N+        + + TGT P  + WLKNG  
Sbjct: 369  IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI--------ECRATGTPPPQINWLKNGLP 420

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      ++L       + I+ A   D   Y CVA N AG         V  P   D   
Sbjct: 421  LPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN-- 476

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                  +   E I  LK      G +   +C   G P P++ W +  + +    +  +S 
Sbjct: 477  ------SMGTEEITVLK------GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST 524

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                  L++ +A  ED G Y C+A N AG V+    LKV +P    ++       +I V 
Sbjct: 525  HG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP---PHINGSEEHEEISVI 579

Query: 4734 EGQPAQFKTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
               P +  T I S I  P + W+++G  +P+T   Q +  G   VL I     EDTG +T
Sbjct: 580  VNNPLEL-TCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYT 636

Query: 4793 CRATTAAG 4800
            C A++ AG
Sbjct: 637  CLASSPAG 644



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/398 (26%), Positives = 155/398 (38%), Gaps = 33/398 (8%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V PS     ++ +    V E      E E +  P P+I WY+    I  S   +I   + 
Sbjct: 92   VPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEI--LAD 149

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
              +L I++  V D+  +   A N  G    + +L V           VPPS     + V 
Sbjct: 150  GQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----------YVPPSIEGPEREVI 199

Query: 4525 V-TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            V T    V L    TG  P  + WLKN K+++     ++    G   L I  +   DSG 
Sbjct: 200  VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 259

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C+A N  G+A+      + +P       P    A  P ++        V  G+ +E  
Sbjct: 260  YTCIASNMEGKAQKYYFLSIQVP-------PSVAGAEIPSDVS-------VLLGENVELV 305

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C   G P P +QW K  K I   +  ++  +A+  TL I  A   D G Y CVA N AG 
Sbjct: 306  CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 365

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                  L V   P    N      L  +V         + + T    P I WL+ G  +P
Sbjct: 366  EDRIFNLNVYVTPTIRGNKDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLP 422

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +   +++  G   V+ I      D   +TC A+  AG
Sbjct: 423  LSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAG 458



 Score =  107 bits (257), Expect = 1e-21
 Identities = 105/407 (25%), Positives = 164/407 (40%), Gaps = 50/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP+   +     V  +       E  G P P I W +E   +  S   + H       L
Sbjct: 1024 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG--RNHAVLPSGGL 1081

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I +   ED+  +  VA+N  GTA     L V+          VPP  +   +   +   
Sbjct: 1082 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ----------VPPVISPHLKEYVIAVD 1131

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            + + L  +  G  P D+ W K+G+ +   IR ++L      +L I    P D+G Y C+A
Sbjct: 1132 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---SLQITFVQPGDAGHYTCMA 1188

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG +    +  V +P       P+ ++      + E          QAI   C   G
Sbjct: 1189 ANVAGSSSTSTKLTVHVP-------PRIRSTEGHYTVNE--------NSQAI-LPCVADG 1232

Query: 4649 KPLPTVQWYKGDKLIKP--SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P + W K + L+     KY     TA+ Y  L +     ED G Y CVA N+AG  T
Sbjct: 1233 IPTPAINWKKDNVLLANLLGKY-----TAEPYGELILENVVLEDSGFYTCVANNAAGEDT 1287

Query: 4706 VAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
                L V        LP  T L  D+ + +G+  +   + T    P + W     +IP  
Sbjct: 1288 HTVSLTV------HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-- 1339

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F  ++   ++ L+I    +ED+GT+ C A  + G V+    + VK
Sbjct: 1340 AHFDSVN--GHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 1384



 Score =  106 bits (255), Expect = 2e-21
 Identities = 82/293 (27%), Positives = 127/293 (43%), Gaps = 23/293 (7%)

Query: 4513 PPSFT-LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            PPS     ++N+ V     + L  +V+G  P D+ WLKN + ++ +    I+   G  TL
Sbjct: 1    PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTL 58

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I+ A   D G+Y C+AIN AGE++      V +P       P  K  ++     E L  
Sbjct: 59   QIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP-------PSIKDHDS-----ESLSV 106

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V EG ++    +    P P + WYK  ++I  S + ++   AD   L I +A   D G
Sbjct: 107  VNVREGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEI--LADGQMLHIKKAEVSDTG 164

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE-GQPAQFKTQITSKIKP 4750
             Y C A N AGR      L V  P   +      P R+++V     P       T    P
Sbjct: 165  QYVCRAINVAGRDDKNFHLNVYVPPSIEG-----PEREVIVETISNPVTLTCDATGIPPP 219

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            TI WL+    I  +   ++      + L I  +   D+G +TC A+   G+ +
Sbjct: 220  TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 272



 Score =  106 bits (255), Expect = 2e-21
 Identities = 122/485 (25%), Positives = 195/485 (40%), Gaps = 59/485 (12%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           ++ G P P +SW + + P+    K +       G  +L I +    D GEYTC A NQ G
Sbjct: 25  EVSGFPPPDLSWLKNEQPI----KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAG 80

Query: 154 EA----ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAY 209
           E+      +VY+ P                   S ++E ++                  Y
Sbjct: 81  ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPVITW--------Y 132

Query: 210 TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS--LGPVSPPK 267
            NG   + +   ++   + ++L       S T +YV  + + ++   D++  L    PP 
Sbjct: 133 KNGRMITESTHVEI-LADGQMLHIKKAEVSDTGQYVCRA-INVAGRDDKNFHLNVYVPPS 190

Query: 268 IAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
           I    R   ++  ++        +G P P + W KN +R+ NS+  E+      + L++ 
Sbjct: 191 IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIA 250

Query: 327 NTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
            +Q SDSG+YT        CI ++    +E   + Y       Y    Q   +    EI 
Sbjct: 251 RSQHSDSGNYT--------CIASN----MEGKAQKY-------YFLSIQVPPSVAGAEIP 291

Query: 387 EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
                        D  V  G+     C   G P P + W  + + I      +I V+ +G
Sbjct: 292 S------------DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 339

Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREG 505
           +  L I     SD+G  TCVA N +GE      LNV     +   K   E+  TL     
Sbjct: 340 S-TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTL---VD 395

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             + +  RA GTP P+I W K+G+P+  +  +R+   G    + I RA+ SD A Y C A
Sbjct: 396 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVIRIVRAQVSDVAVYTCVA 453

Query: 566 QNVAG 570
            N AG
Sbjct: 454 SNRAG 458



 Score =  105 bits (252), Expect = 4e-21
 Identities = 101/382 (26%), Positives = 148/382 (38%), Gaps = 37/382 (9%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E    G P P I W +   P+  S    I   +   ++ I +  V D AV+  VA NR G
Sbjct: 401  ECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 458

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
                  NL V            PP+   ++  + + V  G    +     GT    + WL
Sbjct: 459  VDNKHYNLQV----------FAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 508

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            ++G+ +  D    +        L +L+A  +DSGKY C+A N AGE        V  P  
Sbjct: 509  RDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEP-- 564

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                 P    +    EI        V     +E +C   G P P + W K  + +  +  
Sbjct: 565  -----PHINGSEEHEEI-------SVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD- 611

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             Q+        LRIS A  ED G Y C+A + AG       ++V  P    N+      R
Sbjct: 612  -QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVP---PNIAGTDEPR 667

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            DI V   +    + +  +   P I WLR G  +  TP  +++  G    L I N    DT
Sbjct: 668  DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR--YLQINNADLGDT 725

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
              +TC A+  AG+      L V
Sbjct: 726  ANYTCVASNIAGKTTREFILTV 747



 Score =  104 bits (250), Expect = 7e-21
 Identities = 102/369 (27%), Positives = 147/369 (39%), Gaps = 32/369 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W + +  I+NS   ++   S  S L I +    DS  +  +A N  G A+  
Sbjct: 215  GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 274

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTA--QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L ++          VPPS        +V+V  G+ V L     G     + WLK+GK 
Sbjct: 275  YFLSIQ----------VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKP 324

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +      +I       TL I  A   D+GKY CVA N AGE   D    +++  T     
Sbjct: 325  IASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE--DRIFNLNVYVT----- 377

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  +      E +  L D       +I   C+  G P P + W K    +  S + ++  
Sbjct: 378  PTIRGNKDEAEKLMTLVDT------SINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 429

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             A    +RI  A   D   Y CVA N AG       L+V  P   DN        +I V 
Sbjct: 430  LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT---EEITVL 486

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G              P++ WLR+G   P   D  +    +  VL +     ED+G +TC
Sbjct: 487  KGSSTSMACITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC 544

Query: 4794 RATTAAGQV 4802
             A+  AG+V
Sbjct: 545  IASNEAGEV 553



 Score =  100 bits (239), Expect = 1e-19
 Identities = 101/403 (25%), Positives = 153/403 (37%), Gaps = 42/403 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP          V  + Q     E  G P P I W +    +    +   +   +   L+
Sbjct: 841  PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 900

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    V+D+A +     N  G  K + +L V+          VPPS      +  VT   
Sbjct: 901  IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----------VPPSIADEPTDFLVTKHA 950

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               +    +G     ++W KNG ++ P      +   G   +L  +     +G+Y CVA 
Sbjct: 951  PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL--NHAGRYTCVAR 1008

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVG 4648
            N+AG A                 +  T   + PP +I+P   ++ V     I   C+  G
Sbjct: 1009 NAAGSAH----------------RHVTLHVHEPP-VIQPQPSELHVILNNPILLPCEATG 1051

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P + W K    +  S   +         L+IS A  ED G Y CVA N AG      
Sbjct: 1052 TPSPFITWQKEGINVNTSG--RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKI 1109

Query: 4709 KLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            KL V  P      P ++P L++ V+   +P     +      P I W ++G  I E+   
Sbjct: 1110 KLNVQVP------PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 1163

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +++  G+   L I      D G +TC A   AG   TS KL V
Sbjct: 1164 RVLSSGS---LQITFVQPGDAGHYTCMAANVAGSSSTSTKLTV 1203



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 109/407 (26%), Positives = 170/407 (41%), Gaps = 50/407 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ +  ++   +   +      E DG P P I W+++   I  S   ++ +  +  I  
Sbjct: 1116 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQITF 1175

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++     D+  +  +A N  G++  S  L V           VPP    T  +  V    
Sbjct: 1176 VQP---GDAGHYTCMAANVAGSSSTSTKLTVH----------VPPRIRSTEGHYTVNENS 1222

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILE-AYPQDSGKYECVA 4588
               L     G     + W K+   +  ++  K   E   Y  LILE    +DSG Y CVA
Sbjct: 1223 QAILPCVADGIPTPAINWKKDNVLLA-NLLGKYTAEP--YGELILENVVLEDSGFYTCVA 1279

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+AGE   D    VSL              +  P   E   D  + +G+ +  SCK  G
Sbjct: 1280 NNAAGE---DTH-TVSL------------TVHVLPTFTELPGDVSLNKGEQLRLSCKATG 1323

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             PLP + W   + +I P+ +  ++  ++    R+S+   ED G Y C A NS G V    
Sbjct: 1324 IPLPKLTWTFNNNII-PAHFDSVNGHSELVIERVSK---EDSGTYVCTAENSVGFVKAIG 1379

Query: 4709 KLKVTQPDQ-ADNLPA--LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + V +P     + P+  + PL       G  A    ++     PTIQW R+G  I  + 
Sbjct: 1380 FVYVKEPPVFKGDYPSHWIEPL-------GGNAILNCEVKGDPTPTIQWNRKGVDIEISH 1432

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
              + +  GN ++ + G T  ED G +TC AT  AG VE S  L ++S
Sbjct: 1433 RIRQL--GNGSLAIYG-TVNEDAGDYTCVATNEAGVVERSMSLTLQS 1476



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 79/249 (31%), Positives = 116/249 (46%), Gaps = 18/249 (7%)

Query: 333  SGHYTLLAENPNGC-IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            +GH   + +N N   +++SG L + SP+   V D  +   T T     ++R       + 
Sbjct: 878  NGHLLNVDQNQNSYRLLSSGSLVIISPS---VDDTATYECTVTNGAGDDKRTVDLTVQVP 934

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHA 449
            P       D  VT+       C  +G P+P + W  N  ++  R D  ++IL   SG  A
Sbjct: 935  PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGD-GYRIL--SSG--A 989

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            + I    L+ +G  TCVARN +G       L+V E   V+ P+  E    LN     P++
Sbjct: 990  IEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP-VIQPQPSELHVILN----NPIL 1044

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A GTP+P ITWQK+G+ +  N   R H    +  L I RA   DA  Y C AQN A
Sbjct: 1045 LPCEATGTPSPFITWQKEGINV--NTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 1102

Query: 570  GSTATRARL 578
            G+   + +L
Sbjct: 1103 GTALGKIKL 1111



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 6/158 (3%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C V+G P P+++W  N++ I+ + N  I+    G   L I    +SD G  TC+A N++G
Sbjct: 24  CEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAKVSDGGEYTCIAINQAG 80

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
           E+  +  L V     +      E  S +NVREG  V L   +   P P ITW K+G  I 
Sbjct: 81  ESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLEXESNAVPPPVITWYKNGRMIT 139

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +  + I  DG    L I +A+ SD   Y C A NVAG
Sbjct: 140 ESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAG 175



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 97/379 (25%), Positives = 156/379 (41%), Gaps = 41/379 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++  P+  +   Q+ T     +L I    VED+  +  +A +  G     
Sbjct: 592  GIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD---- 645

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQ--NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++K    R   VPP+   T +  ++ V   + V L+ K     P  + WL+NG++
Sbjct: 646  -----DDKEYLVRVH-VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER 699

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            +Q   R +IL   G Y L I  A   D+  Y CVA N AG+   +    V++P       
Sbjct: 700  LQATPRVRIL-SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP------- 750

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P  K    P  ++  L    V E       C   G P P + W K D  +    + + S 
Sbjct: 751  PNIK--GGPQSLVILLNKSTVLE-------CIAEGVPTPRITWRK-DGAVLAGNHARYSI 800

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVV 4732
              + + L I  A   D G Y C+A N+AG       L+V  P      P++ P   ++ V
Sbjct: 801  LENGF-LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP------PSIAPGPTNMTV 853

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                      + T   KP+I W + G L+    +       ++  L+I +   +DT T+ 
Sbjct: 854  IVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE 913

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C  T  AG  + +  L V+
Sbjct: 914  CTVTNGAGDDKRTVDLTVQ 932



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 84/289 (29%), Positives = 122/289 (42%), Gaps = 43/289 (14%)

Query: 290 SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
           SG P P++TW K+G+ L  ++  ++ T      LR+   Q  D+G YT        C+ +
Sbjct: 591 SGIPAPKMTWMKDGRPLPQTD--QVQTLGGGEVLRISTAQVEDTGRYT--------CLAS 640

Query: 350 SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
           S   A +   E  V+      I  T +               P+ + V ++R VT     
Sbjct: 641 SP--AGDDDKEYLVRVHVPPNIAGTDE---------------PRDITVLRNRQVT----- 678

Query: 410 RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
             +C+    P P +TW  N  +++     +IL   SG   L I N  L D+   TCVA N
Sbjct: 679 -LECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASN 734

Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
            +G+T  +  L V      V P       +L +   +  VL   A G PTPRITW+KDG 
Sbjct: 735 IAGKTTREFILTVN-----VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 789

Query: 530 PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +  N       + G   L I  A  +D   Y C A N AG+   R  L
Sbjct: 790 VLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 836



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 13/167 (7%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            C  TG P P +TW      +     NH +L   SG   L I+     D+G   CVA+N +
Sbjct: 1047 CEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGG--LQISRAVREDAGTYMCVAQNPA 1102

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G    + +LNV +   V++P   E    ++    +P+ L+  A G P P ITW KDG  I
Sbjct: 1103 GTALGKIKLNV-QVPPVISPHLKEYVIAVD----KPITLSCEADGLPPPDITWHKDGRAI 1157

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + +   R+ + G   +L I   +  DA  Y C A NVAGS++T  +L
Sbjct: 1158 VESIRQRVLSSG---SLQITFVQPGDAGHYTCMAANVAGSSSTSTKL 1201



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 74/311 (23%), Positives = 128/311 (41%), Gaps = 40/311 (12%)

Query: 265 PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           PP +A  + P +  +  G + +     +G P P + W K+G+ + +     I  + N +T
Sbjct: 282 PPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGST 341

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
           L +     SD+G YT        C+ T+      +  E  + +  + Y+T T +   +E 
Sbjct: 342 LNIYGALTSDTGKYT--------CVATN-----PAGEEDRIFNL-NVYVTPTIRGNKDE- 386

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
              +EK +         D  +        +CR TG P P++ W  N   +    + ++L 
Sbjct: 387 ---AEKLMT------LVDTSIN------IECRATGTPPPQINWLKNGLPLPLSSHIRLL- 430

Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
             +    + I    +SD  V TCVA N++G       L V     +      E  + L  
Sbjct: 431 --AAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL-- 486

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
            +G    +     GTP P + W +DG P+  +  L + T G    L + +A+  D+  Y 
Sbjct: 487 -KGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG--MVLQLLKAETEDSGKYT 543

Query: 563 CTAQNVAGSTA 573
           C A N AG  +
Sbjct: 544 CIASNEAGEVS 554



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 92/398 (23%), Positives = 147/398 (36%), Gaps = 39/398 (9%)

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            T + +   V  + Q   E + D  P P+I W R    ++ +P  ++   S    L I   
Sbjct: 663  TDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--RVRILSGGRYLQINNA 720

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRL 4533
             + D+A +  VA N  G       L V           VPP+     Q++ +   +   L
Sbjct: 721  DLGDTANYTCVASNIAGKTTREFILTVN----------VPPNIKGGPQSLVILLNKSTVL 770

Query: 4534 DTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    G     + W K+G  +  +     + E+G   L I  A+  D+G+Y C+A N+AG
Sbjct: 771  ECIAEGVPTPRITWRKDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAG 828

Query: 4594 EARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
              R   +  V                + PP I     +  V        +C+  G P P+
Sbjct: 829  TDRRRIDLQV----------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 872

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + W K   L+   +     R     +L I     +D   Y+C   N AG       L V 
Sbjct: 873  INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 932

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG-ALIPETPDFQMIHE 4772
             P    + P      D +V +  PA      +    P+I W + G  L+P    ++++  
Sbjct: 933  VPPSIADEPT-----DFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 987

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G   +L    T     G +TC A  AAG       L V
Sbjct: 988  GAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLHV 1022



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 39/403 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP      Q   +  ++    E   +G P P I W ++   +  +     ++      L 
Sbjct: 750  PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGN--HARYSILENGFLH 807

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+   V D+  +  +A N  GT +   +L V           VPPS      N+ V    
Sbjct: 808  IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----------VPPSIAPGPTNMTVIVNV 857

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
               L  + TG     + W KNG  +  D          + +L+I+     D+  YEC   
Sbjct: 858  QTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 917

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AG+ +   +  V +P                P I +   D +V +      +C   G 
Sbjct: 918  NGAGDDKRTVDLTVQVP----------------PSIADEPTDFLVTKHAPAVITCTASGV 961

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P++ W K G +L+     +++  +     + I        G Y CVA N+AG      
Sbjct: 962  PFPSIHWTKNGIRLLPRGDGYRILSSG---AIEILATQLNHAGRYTCVARNAAGSAHRHV 1018

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             L V +P      P+     ++ V    P     + T    P I W +EG  +  +    
Sbjct: 1019 TLHVHEPPVIQPQPS-----ELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNH 1073

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +       L I     ED GT+ C A   AG      KL V+
Sbjct: 1074 AVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 1114



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 51/168 (30%), Positives = 77/168 (45%), Gaps = 8/168 (4%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V +G  T   C   G P P + W  + + +  D +  + V+  G   L +      DSG 
Sbjct: 485 VLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAH--LTVSTHGM-VLQLLKAETEDSGK 541

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TC+A N++GE +    L V+E   +      E    ++V    P+ L   A G P P++
Sbjct: 542 YTCIASNEAGEVSKHFILKVLEPPHINGS---EEHEEISVIVNNPLELTCIASGIPAPKM 598

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           TW KDG P +P  + ++ T GG   L I  A+  D   Y C A + AG
Sbjct: 599 TWMKDGRP-LPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 644



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 12/168 (7%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V E       C   G P P + W   D  +  +   K      G   L++ NV L DSG 
Sbjct: 1218 VNENSQAILPCVADGIPTPAINWK-KDNVLLANLLGKYTAEPYGE--LILENVVLEDSGF 1274

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             TCVA N +GE      L V      V P F E    +++ +GE + L+ +A G P P++
Sbjct: 1275 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 1329

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            TW  +   IIP       +  G S L I R    D+  Y CTA+N  G
Sbjct: 1330 TWTFNN-NIIP---AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 1373



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 41/299 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+      + + EQ R   +  G PLP + W   N    N       + +  S L+I
Sbjct: 1298 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN----NIIPAHFDSVNGHSELVI 1353

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVTSG 4528
             +V  EDS  +   AEN  G  K    + V+E          PP F     +  +    G
Sbjct: 1354 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKE----------PPVFKGDYPSHWIEPLGG 1403

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ +V G     + W  N K V  +I ++I  + G  +L I     +D+G Y CVA
Sbjct: 1404 NAI-LNCEVKGDPTPTIQW--NRKGVDIEISHRI-RQLGNGSLAIYGTVNEDAGDYTCVA 1459

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIV 4647
             N AG        VV         +  +    +PP I +EP++  I A G+ I  +C+  
Sbjct: 1460 TNEAG--------VVE--------RSMSLTLQSPPIITLEPVETVINAGGKII-LNCQAT 1502

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G+P PT+ W +    I    +          +L I++A  ED  +++CVA N  G V V
Sbjct: 1503 GEPQPTITWSRQGHSI---SWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLV 1558



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 6/190 (3%)

Query: 4622 PPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            PP +I P  + + V     I  +C++ G P P + W K ++ IK +    +       TL
Sbjct: 1    PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI--VPGGRTL 58

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            +I  A   D G+Y C+A N AG       L V  P    +  + + L  + V EG     
Sbjct: 59   QIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-LSVVNVREGTSVSL 117

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + +  +   P I W + G +I E+   +++ +G   +L I      DTG + CRA   AG
Sbjct: 118  EXESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAG 175

Query: 4801 QVETSAKLVV 4810
            + + +  L V
Sbjct: 176  RDDKNFHLNV 185



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 46/164 (28%), Positives = 81/164 (49%), Gaps = 12/164 (7%)

Query: 412  DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
            +C V G P P + W  N + +  + +H+I   + GN +L I      D+G  TCVA N++
Sbjct: 1408 NCEVKGDPTPTIQW--NRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEA 1463

Query: 472  GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            G       L  ++   ++  + VE      +  G  ++LN +A G P P ITW + G  I
Sbjct: 1464 GVVERSMSLT-LQSPPIITLEPVETV----INAGGKIILNCQATGEPQPTITWSRQGHSI 1518

Query: 532  IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
              +  + + ++   ++L I  A+  D + ++C A+N+ GS   R
Sbjct: 1519 SWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLMGSVLVR 1559



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 51/164 (31%), Positives = 73/164 (44%), Gaps = 11/164 (6%)

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            K     C   G P P++TW  + R I +    ++L   SG+  L IT V   D+G  TC+
Sbjct: 1132 KPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL--SSGS--LQITFVQPGDAGHYTCM 1187

Query: 467  ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
            A N +G ++   +L V      V P+         V E    +L   A G PTP I W+K
Sbjct: 1188 AANVAGSSSTSTKLTVH-----VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 1242

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            D V ++ N  L  +T      L +      D+ +Y C A N AG
Sbjct: 1243 DNV-LLAN-LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 1284



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 14/180 (7%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F ++  D  + +G+  R  C+ TG P P++TW  N+  I   ++     + +G+  L+
Sbjct: 1298 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELV 1352

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVL 510
            I  V+  DSG   C A N  G   F   +  +  ++   P F   + +  +   G   +L
Sbjct: 1353 IERVSKEDSGTYVCTAENSVG---FVKAIGFVYVKE--PPVFKGDYPSHWIEPLGGNAIL 1407

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            N    G PTP I W + GV I  +  +R     G  +L I      DA  Y C A N AG
Sbjct: 1408 NCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 1464



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 15/235 (6%)

Query: 347  IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
            I+ +G+L ++S   ++V D        T    T+ R    +  + P       +  V   
Sbjct: 800  ILENGFLHIQS---AHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 856

Query: 407  KMTRFDCRVTGRPYPEVTWFINDRQIRDDYN-HKILVNESGNHALMITNVTLSDSGVVTC 465
              T   C  TG P P + W  N   +  D N +   +  SG+  L+I + ++ D+    C
Sbjct: 857  VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS--LVIISPSVDDTATYEC 914

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
               N +G+      L V      V P   +  +   V +  P V+   A G P P I W 
Sbjct: 915  TVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 969

Query: 526  KDGVPIIPNPE-LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            K+G+ ++P  +  RI + G    ++I   + + A  Y C A+N AGS      L+
Sbjct: 970  KNGIRLLPRGDGYRILSSGA---IEILATQLNHAGRYTCVARNAAGSAHRHVTLH 1021



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 74/294 (25%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
           +G+         G P P + W ++GQ L   + H  ++TH    L++   +  DSG YT 
Sbjct: 487 KGSSTSMACITDGTPAPSMAWLRDGQPL-GLDAHLTVSTHG-MVLQLLKAETEDSGKYTC 544

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
           +A N  G +     L V  P           +I  +++ E     EIS     P     C
Sbjct: 545 IASNEAGEVSKHFILKVLEP----------PHINGSEEHE-----EISVIVNNP-LELTC 588

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
               +   KMT       GRP P+        Q++            G   L I+   + 
Sbjct: 589 IASGIPAPKMTWMK---DGRPLPQTD------QVQ---------TLGGGEVLRISTAQVE 630

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           D+G  TC+A + +G+   +  + V     +         + L  R+   V L  ++   P
Sbjct: 631 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ---VTLECKSDAVP 687

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            P ITW ++G  +   P +RI +  G   L I  A   D A Y C A N+AG T
Sbjct: 688 PPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGKT 739



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 16/172 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD +  I+W   G  IE SHRIR +   G   L I GT   D+G Y+C ATN+ G  E S
Sbjct: 1413 GDPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 1469

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + L        Q P   T ++ +E  +  G      C      +P   I W   G  +  
Sbjct: 1470 MSLTL------QSPPIIT-LEPVETVINAGGKIILNCQA--TGEPQPTITWSRQGHSISW 1520

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGG 3246
              R+  +S+    + D    Q  D+ E+ C A N  G    R  +     GG
Sbjct: 1521 DDRVNVLSNNSLYIAD---AQKEDTSEFECVARNLMGSVLVRVPVIVQVHGG 1569



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 77/307 (25%), Positives = 121/307 (39%), Gaps = 40/307 (13%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P  I  K  N  +          ++SG P P ++W KN Q  I  N + +I      TL+
Sbjct: 2   PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQP-IKLNTNTLIVPGGR-TLQ 59

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE-TEERI 383
           +   + SD G YT +A N  G       L V  P    ++D  S+ ++    RE T   +
Sbjct: 60  IIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTSVSL 117

Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
           E    A+ P  +   ++     G+M      +T   + E+   + D Q+   +  K  V+
Sbjct: 118 EXESNAVPPPVITWYKN-----GRM------ITESTHVEI---LADGQML--HIKKAEVS 161

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
           ++G +     NV               +G       LNV     +  P+      T++  
Sbjct: 162 DTGQYVCRAINV---------------AGRDDKNFHLNVYVPPSIEGPEREVIVETIS-- 204

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
              PV L   A G P P I W K+   I  +  L +    G S L I R++ SD+  Y C
Sbjct: 205 --NPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTC 262

Query: 564 TAQNVAG 570
            A N+ G
Sbjct: 263 IASNMEG 269



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 46/162 (28%), Positives = 75/162 (46%), Gaps = 10/162 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + W  N + I+ +    T+   G   L+I+  K +D G Y+C A N+ G+++    L   
Sbjct: 34   LSWLKNEQPIKLN--TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 91

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S       +  + N+   ++G S   E     V  P   I WY NG+ +  ST ++ 
Sbjct: 92   VPPSIKDHDSESLSVVNV---REGTSVSLEXESNAVPPP--VITWYKNGRMITESTHVEI 146

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++D    +L I   +  D+G+YVCRA N  G D     +N Y
Sbjct: 147  LADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY 186



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 62/288 (21%), Positives = 104/288 (36%), Gaps = 17/288 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP+     K    A         +  G P P ++W +    +VE    S+R    +   S
Sbjct: 1116 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE----SIRQRVLSSG-S 1170

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I  + PGD G YTC A N  G +  S  +                   +    +   A
Sbjct: 1171 LQITFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA 1230

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             G    T   + +   V   N     + + +     E  +L +  F   +     GE   
Sbjct: 1231 DGIP--TPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTH 1288

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +S  +         P   + P +  L +G   +   + +G P P++TW  N   +I ++
Sbjct: 1289 TVSLTVHVL------PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNN-IIPAH 1341

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
               +   + H+ L +    K DSG Y   AEN  G +   G++ V+ P
Sbjct: 1342 FDSV---NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 1386



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            I  G  +  + W  +G+ +     + TV   GMV L++L  +T DSG Y+C A+N+ G+ 
Sbjct: 496  ITDGTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSGKYTCIASNEAGEV 553

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
                 L+ ++      P      +  E +    +   E T +    P  K+ W  +G+P+
Sbjct: 554  SKHFILKVLE------PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL 607

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              + +++T+   G  VL I+  Q  D+G Y C A +  G+D
Sbjct: 608  PQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSPAGDD 646



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +  S  IR + A G V+  I+  + +D   Y+C A+N+ G    
Sbjct: 405  TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYTCVASNRAGVDNK 462

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               L+            T  I  ++    G S    C       P M   W  +GQP+  
Sbjct: 463  HYNLQVFAPPNMDNSMGTEEITVLK----GSSTSMACITDGTPAPSM--AWLRDGQPLGL 516

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + TVS  G +VL +   +  DSG+Y C A N+ GE
Sbjct: 517  DAHL-TVSTHG-MVLQLLKAETEDSGKYTCIASNEAGE 552



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 8/164 (4%)

Query: 407 KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
           K T  +C   G P P +TW   D  +    + +  + E+G   L I +  ++D+G   C+
Sbjct: 766 KSTVLECIAEGVPTPRITWR-KDGAVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCM 822

Query: 467 ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
           A N +G    +  L V      V P      + + V       L   A G P P I W+K
Sbjct: 823 ATNAAGTDRRRIDLQVH-----VPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK 877

Query: 527 DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           +G  +  +     +    + +L I      D A Y+CT  N AG
Sbjct: 878 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAG 921



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 10/170 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     I W  N K IE S  +      G   L+I  ++ +DSG Y+C A+N  G+A+ 
Sbjct: 214  TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 273

Query: 3134 -ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
               + ++      G        I +   +  G++    C    +  P   I+W  +G+P+
Sbjct: 274  YYFLSIQVPPSVAG------AEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPI 325

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
                  +         L+I      D+G+Y C A N  GE+     +N Y
Sbjct: 326  ASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 375



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   ++W R GV IE S+R+  + + G +A+    VN ED+G YTC A NE G    S
Sbjct: 1413 GDPTPTIQWNRKGVDIEISHRIRQLGN-GSLAI-YGTVN-EDAGDYTCVATNEAGVVERS 1469

Query: 1798 STLFVQSKASLQLE 1811
             +L +QS   + LE
Sbjct: 1470 MSLTLQSPPIITLE 1483



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 13/168 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  S  I W   G  +  S R   V   G   L+I      D+GTY C A N  G A  
Sbjct: 1050 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 1107

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
             +KL          P  + H++      D +     C    +  PD  I W+ +G+ +  
Sbjct: 1108 KIKLNVQ-----VPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVE 1159

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            S R + +S      L I + Q  D+G Y C A N  G   T   +  +
Sbjct: 1160 SIRQRVLSSGS---LQITFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 1204



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  + G NV L C     G  T  ++W  +GKPI +G   R     +   L++      
Sbjct: 293  DVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTS 350

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            D+G YTC ATN  GE      L V     +     +    EK+  L DTS
Sbjct: 351  DTGKYTCVATNPAGEEDRIFNLNVYVTPTI---RGNKDEAEKLMTLVDTS 397



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP F     SH +E   G       E K DP   I+W R G  +   HR R    +G
Sbjct: 1383 VKEPPVFKGDYPSHWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLG 1438

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              SL I     ED+G+Y C A N+ G      +++ +  P I L+
Sbjct: 1439 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 1483



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F  +   +   P GG    +C V+  GDPT  I W   G       R+  L + G +
Sbjct: 1386 PPVFKGDYPSHWIEPLGGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIRQLGN-GSL 1442

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
            A  I      DAG+YTC ATN+ G    +  +T  +   I LE
Sbjct: 1443 A--IYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 1483



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +  +K+ + +    P+   C  +  G P   I W  +GR      R   L+     
Sbjct: 1116 PPVISPHLKEYV-IAVDKPITLSCEAD--GLPPPDITWHKDGRAIVESIRQRVLSSG--- 1169

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +L I ++   DAG YTC A N  GS++T+ K+T
Sbjct: 1170 SLQITFVQPGDAGHYTCMAANVAGSSSTSTKLT 1202



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 71   PPIFEQIFKNARFAQ-GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP+F+  + +      GGNA    +++G+PTP + W RK   +    + S R   Q G+ 
Sbjct: 1386 PPVFKGDYPSHWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDI----EISHRI-RQLGNG 1440

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I      D G+YTC A N+ G
Sbjct: 1441 SLAIYGTVNEDAGDYTCVATNEAG 1464



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 58/262 (22%), Positives = 97/262 (37%), Gaps = 16/262 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G PTP ++W  KK  ++  N       E  G+  L+++ +   D G YTC A N  GE  
Sbjct: 1232 GIPTPAINW--KKDNVLLANLLGKYTAEPYGE--LILENVVLEDSGFYTCVANNAAGEDT 1287

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +                  +     +  KA G             K+ +T   +  
Sbjct: 1288 HTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIP---------LPKLTWTFNNNII 1338

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  V+     ++  VS  +S T     E+ V     I        P      P +  
Sbjct: 1339 PAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSHWI 1398

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
               G +A    ++ G+P P + W + G  +  S++   I    + +L +  T   D+G Y
Sbjct: 1399 EPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDY 1455

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
            T +A N  G +  S  L ++SP
Sbjct: 1456 TCVATNEAGVVERSMSLTLQSP 1477



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 35/163 (21%), Positives = 68/163 (41%), Gaps = 4/163 (2%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E   SL   SPP I  +P  + +  G       Q +G P+P +TW + G  +   ++  +
Sbjct: 1467 ERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 1526

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
            +   ++ +L + + QK D+  +  +A N  G ++    + V+     + Q    +  + T
Sbjct: 1527 L---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ-VHGGFSQWSAWRACSVT 1582

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              +  ++R  +  + L     K CQ  D+         C V G
Sbjct: 1583 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 1625



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 1318 HNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYP 1377
            H IE + G N  L C ++  GD T  ++W   G  I+  HR R   +    +L +     
Sbjct: 1396 HWIEPLGG-NAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVN 1449

Query: 1378 EDSGVYTCQATNQLGEAVTSCALRVIAKKDLILE 1411
            ED+G YTC ATN+ G    S +L + +   + LE
Sbjct: 1450 EDAGDYTCVATNEAGVVERSMSLTLQSPPIITLE 1483



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKL 3138
            VI W  NG+ ++A+ R+R +   G   L+I      D+  Y+C A+N  G+   E  + +
Sbjct: 690  VITWLRNGERLQATPRVRIL--SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 747

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
                  KG  P+    + N       +S   EC    V  P  +I W  +G  +  +   
Sbjct: 748  NVPPNIKG-GPQSLVILLN-------KSTVLECIAEGVPTP--RITWRKDGAVLAGNHAR 797

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
             ++ + GF+ +  A+    D+G Y+C A N  G D  R  +  +
Sbjct: 798  YSILENGFLHIQSAHVT--DTGRYLCMATNAAGTDRRRIDLQVH 839



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTL 323
            PP IA +P +  + + A A      SG P P + W KNG RL+   + + I+++     +
Sbjct: 934  PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS---GAI 990

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             +  TQ + +G YT +A N  G       L V  P    +Q Q S+
Sbjct: 991  EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP--PVIQPQPSE 1034



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 7/123 (5%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            Q P  +     P+ +S   G++    C     P P   ++W  +GK + SG   R     
Sbjct: 280  QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSA 337

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              + L+I      D+G+YTC A N  G+      LNV    + IR ++ E+  EK+  L 
Sbjct: 338  NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEA--EKLMTLV 394

Query: 1960 DDS 1962
            D S
Sbjct: 395  DTS 397



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + V+  P F T+L G   L++G+     C+    P P  ++ W FN  ++ +   + +
Sbjct: 1290 VSLTVHVLPTF-TELPGDVSLNKGEQLRLSCKATGIPLP--KLTWTFNNNIIPA--HFDS 1344

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
             N  G + L I  V  EDSG Y C A N++G
Sbjct: 1345 VN--GHSELVIERVSKEDSGTYVCTAENSVG 1373



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A   C ++  P P   ++W   G  ++  HR R     G  +L I     ED+G+YT
Sbjct: 1402 GGNAILNCEVKGDPTPT--IQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 1456

Query: 1919 CKAINNLGQAVSSIRLNVQS 1938
            C A N  G    S+ L +QS
Sbjct: 1457 CVATNEAGVVERSMSLTLQS 1476



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDGR +  S R     + G + +T   V   DAGHYTC A N  G ++TS  LT+
Sbjct: 1148 ITWHKDGRAIVESIR-QRVLSSGSLQITF--VQPGDAGHYTCMAANVAGSSSTSTKLTV 1203



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 265 PPKIA--QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           PP IA   +PR+  +        + +    P P +TW +NG+RL  + +  I++   +  
Sbjct: 657 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY-- 714

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           L++ N    D+ +YT +A N  G       L V  P
Sbjct: 715 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVP 750



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A   C V+   DP  TI W   G  I   HR R     G  +L I  T  ED+G Y 
Sbjct: 1402 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 1456

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILD 2210
            C ATN+ G    + +L +     I L+
Sbjct: 1457 CVATNEAGVVERSMSLTLQSPPIITLE 1483



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  GDPT  I+W + G  IE S R   I + G  SL +     +D+G+YTC A +  GV 
Sbjct: 1410 EVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 1466

Query: 721  E--TKAVLHVTPRATIE 735
            E      L   P  T+E
Sbjct: 1467 ERSMSLTLQSPPIITLE 1483



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 632 RVYPPPQF--IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
           +V+ PP     +  + +T ++G         +  G P   + WL++GQ +   +  T + 
Sbjct: 467 QVFAPPNMDNSMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLT-VS 523

Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE 742
             G + L +L    +DSG+YTC A +  G      +L V     I  + +H E
Sbjct: 524 THGMV-LQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 575



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WLR+G P+     LT +   G V L +     EDSG YTC A NE GE    
Sbjct: 499  GTPAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGEVSKH 556

Query: 1798 STLFVQSKASLQLESQHE 1815
              L V     +    +HE
Sbjct: 557  FILKVLEPPHINGSEEHE 574



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E + I +G  +  + W  +G+ +  + +++T+   G  VL I   +  D+G Y+C A++ 
Sbjct: 585  ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 642

Query: 3129 WGQ--AEISVKLECVDKSKG-QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
             G    E  V++       G  +PR  T ++N       +    EC    V  P   I W
Sbjct: 643  AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN-------RQVTLECKSDAVPPP--VITW 693

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              NG+ ++ + R++ +S  G   L I      D+  Y C A N  G+
Sbjct: 694  LRNGERLQATPRVRILS--GGRYLQINNADLGDTANYTCVASNIAGK 738



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V+ PP      +S  +  ++    EC  E    P  RI W ++G +L   H   ++ + G
Sbjct: 747  VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENG 804

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            F  L I   +  D+G Y+C A N  G D  +  +     P I
Sbjct: 805  F--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 844



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F  LP  V++ +GE  R  C+ TG P P++ W  N N I
Sbjct: 1298 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 1338



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            +V+ G++V   C    +      ++W K+G+P+  G   R         L+I   +  D+
Sbjct: 295  SVLLGENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 352

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            G YTC A N  G ++    L     T  +R  ++EA  E++  L D S
Sbjct: 353  GKYTCVATNPAGEEDRIFNLNV-YVTPTIRGNKDEA--EKLMTLVDTS 397



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+N+   CN      PT  I+W  + KP+ SG   +     +  +L+I      D+G YT
Sbjct: 299  GENVELVCNANGI--PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 356

Query: 2848 CKATNSKG 2855
            C ATN  G
Sbjct: 357  CVATNPAG 364



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP     +K + +   + +   C  +    P   I W+++G+ +    R R V   G
Sbjct: 1113 VQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR-VLSSG 1169

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
              SL I +V   D+G Y C A N  G   T   ++    P I
Sbjct: 1170 --SLQITFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 1209



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+F     S+     G +  L  +V  + DP   I+W + GV +    R++     
Sbjct: 1383 VKEPPVFKGDYPSHWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQ---L 1437

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G  +L+I    N+D+G YTC ATN  G    + S+ ++
Sbjct: 1438 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 1475



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 8/137 (5%)

Query: 3171 CTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
            C V     PD+   W  N QP++ +T    V   G   L I   +  D GEY C A N+ 
Sbjct: 24   CEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAINQA 79

Query: 3231 GEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA----EPPKFIT 3286
            GE   + ++  Y    +     +  S+  +RE  S+    +     P      +  + IT
Sbjct: 80   GESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPVITWYKNGRMIT 139

Query: 3287 QIQDVTKLVEGQSAHFE 3303
            +   V  L +GQ  H +
Sbjct: 140  ESTHVEILADGQMLHIK 156



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            D    ++W + G  + I HR R +   G  +L I   + ED+G YTC A N  G  E S 
Sbjct: 1414 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 1470

Query: 1533 RLTCRS 1538
             LT +S
Sbjct: 1471 SLTLQS 1476



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     EI  ++ V  G  V   C     G PT  I W  +G+P A+G           
Sbjct: 282  PPSVAGAEIPSDVSVLLGENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANG 339

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L+I      D G+YTC ATN  G
Sbjct: 340  STLNIYGALTSDTGKYTCVATNPAG 364



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            PT  ++W  +G+P+  G   +         L+I  A   DTG Y C ATN  GE
Sbjct: 312  PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 365



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)

Query: 3047 PPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP  +   K+ ++ + +      EA  +P  D    I W  +G+ I  S R R V + G 
Sbjct: 1116 PPVISPHLKEYVIAVDKPITLSCEADGLPPPD----ITWHKDGRAIVESIRQR-VLSSGS 1170

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LK 3162
              L+I   +  D+G Y+C A N  G +  S KL     +    PR    I++ EG   + 
Sbjct: 1171 --LQITFVQPGDAGHYTCMAANVAGSSSTSTKL-----TVHVPPR----IRSTEGHYTVN 1219

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +   A   C    +  P   I W  +   + +     T   +G ++L+    +  DSG Y
Sbjct: 1220 ENSQAILPCVADGIPTP--AINWKKDNVLLANLLGKYTAEPYGELILENVVLE--DSGFY 1275

Query: 3223 VCRAYNKYGED 3233
             C A N  GED
Sbjct: 1276 TCVANNAAGED 1286



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 2/71 (2%)

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           + L     G P P ++W K+  PI  N    I    G  TL I RAK SD   Y C A N
Sbjct: 20  ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGRTLQIIRAKVSDGGEYTCIAIN 77

Query: 568 VAGSTATRARL 578
            AG +  +  L
Sbjct: 78  QAGESKKKFSL 88



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 1068 EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            E + D T T++W   G  I  ++RI+     G  +L I     ED+G YT VA N AG  
Sbjct: 1410 EVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 1466

Query: 1128 QLSASMTVET 1137
            + S S+T+++
Sbjct: 1467 ERSMSLTLQS 1476



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  ++W + G  +E S RI      G  +L I      DAG YTC A N  G    S
Sbjct: 1413 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERS 1469

Query: 997  ANLTIVTKKDIIAE 1010
             +LT+ +   I  E
Sbjct: 1470 MSLTLQSPPIITLE 1483



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 633 VYPPPQF----IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
           VY PP         L  V   EG  +  E     V  P   I W KNG+ I  S+    I
Sbjct: 90  VYVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPV--ITWYKNGRMITESTH-VEI 146

Query: 689 FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE 735
              G + L +    + D+G+Y CRA++  G  +    L+V    +IE
Sbjct: 147 LADGQM-LHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE 192



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+N+ L C     G PT  ++W  +G+ +  G   +         L+I  A ++DTG+YT
Sbjct: 299  GENVELVCNAN--GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 356

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDT--QNEQAIEQIQLLEDAA 1295
              A N  G        R+   +  VT T   N+   E++  L D +
Sbjct: 357  CVATNPAGEED-----RIFNLNVYVTPTIRGNKDEAEKLMTLVDTS 397



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 5/94 (5%)

Query: 636 PPQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PP  I P  +++T +    I     +   G P   + WLKN Q I+ ++   ++   G  
Sbjct: 1   PPSVIGPKSENLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTN--TLIVPGGR 56

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           +L ++   + D GEYTC A++  G ++ K  L V
Sbjct: 57  TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 90



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 2/73 (2%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V   EG       E    P   I WY+NG+++        + D     L I      D+G
Sbjct: 107  VNVREGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 164

Query: 3901 EYICRAVNDFGED 3913
            +Y+CRA+N  G D
Sbjct: 165  QYVCRAINVAGRD 177



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
           ++EG +   E +   V  P   + WYK+GR IT S+ +  I   G + L+I      D G
Sbjct: 109 VREGTSVSLEXESNAVPPPV--ITWYKNGRMITESTHV-EILADGQM-LHIKKAEVSDTG 164

Query: 842 SYTVRAVNKLG 852
            Y  RA+N  G
Sbjct: 165 QYVCRAINVAG 175



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  ++WLKDG+P+ +        +     L I      D G YTC A N  G+    
Sbjct: 310  GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 369

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
             NL +     I          EK+  L D S
Sbjct: 370  FNLNVYVTPTIRGNKDE---AEKLMTLVDTS 397



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYP 3487
            ++ N+REG +   E        P   + WY NG+ +   +      D    +L I     
Sbjct: 105  SVVNVREGTSVSLEXESNAVPPP--VITWYKNGRMITESTHVEILADGQ--MLHIKKAEV 160

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
             D+G+Y+CRA N  G          +  +N  L   +P  +EG  ++   +E  S  V T
Sbjct: 161  SDTGQYVCRAINVAG----------RDDKNFHLNVYVPPSIEGP-EREVIVETISNPV-T 208

Query: 3548 LTPEAESGNPP 3558
            LT +A +G PP
Sbjct: 209  LTCDA-TGIPP 218



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 4/83 (4%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S+ NV EG  V  E +   V      + W+KNG+ +T       + D G + L I     
Sbjct: 105  SVVNVREGTSVSLEXESNAVPPP--VITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 160

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRL 1534
             D+G Y CRA+N+ G D+ +  L
Sbjct: 161  SDTGQYVCRAINVAGRDDKNFHL 183



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            +   VQ  P+ + HLK Y   V+ + + L  + +    P+  I W K+G  +    R + 
Sbjct: 1109 IKLNVQVPPVISPHLKEYVIAVD-KPITLSCEADGLPPPD--ITWHKDGRAIVESIRQR- 1164

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                G  +L I  ++  D+G YTC A N+ G + ++  + +
Sbjct: 1165 VLSSG--SLQITFVQPGDAGHYTCMAANVAGSSSTSTKLTV 1203



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  V LE     V  P   + WY NGR + +    +   D G + L I  A   DTG
Sbjct: 109  VREGTSVSLEXESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSDTG 164

Query: 2049 TYMCKATNAVG 2059
             Y+C+A N  G
Sbjct: 165  QYVCRAINVAG 175



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 11/110 (10%)

Query: 626 PPGEED-----RVYPPPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
           P G++D     RV+ PP        + +T +   ++  E + + V  P   I WL+NG+ 
Sbjct: 642 PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGER 699

Query: 679 IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           ++A+ R   +    Y+ ++  + ++ D+  YTC A +  G    + +L V
Sbjct: 700 LQATPRVRILSGGRYLQIN--NADLGDTANYTCVASNIAGKTTREFILTV 747



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 7/131 (5%)

Query: 3557 PPEFTTT-PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP F    PS  I     +A   C +    D +  ++W   G  +    R++ + +    
Sbjct: 1386 PPVFKGDYPSHWIEPLGGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRIRQLGNGS-- 1441

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I G    DAG YTC ATN  G    S  L ++    I LEP + +   +G + I   
Sbjct: 1442 -LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEP-VETVINAGGKIILNC 1499

Query: 3676 EETLHKREEIT 3686
            + T   +  IT
Sbjct: 1500 QATGEPQPTIT 1510



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/69 (30%), Positives = 30/69 (43%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           PT  ++W KDG+PI +        +    +LNI      D G YT  A N  GE     +
Sbjct: 312 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 371

Query: 860 IRVAARSTV 868
           + V    T+
Sbjct: 372 LNVYVTPTI 380



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 47/262 (17%), Positives = 93/262 (35%), Gaps = 12/262 (4%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P ++W RK   L+  ++    Y   +   SL+I      D   Y CT  N  G+  
Sbjct: 867  GIPKPSINW-RKNGHLLNVDQNQNSYRLLSSG-SLVIISPSVDDTATYECTVTNGAGDDK 924

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
             +V +  +               +H    +   A G    +   ++   ++    G  + 
Sbjct: 925  RTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLL-PRGDGYR 983

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                  ++    +L     +   + +   G +   ++  +        PP I  +P    
Sbjct: 984  ILSSGAIEILATQLNHAGRYT-CVARNAAGSAHRHVTLHVHE------PPVIQPQPSELH 1036

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +          + +G P P +TW K G  +  S ++  +       L++    + D+G Y
Sbjct: 1037 VILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTY 1094

Query: 337  TLLAENPNGCIVTSGYLAVESP 358
              +A+NP G  +    L V+ P
Sbjct: 1095 MCVAQNPAGTALGKIKLNVQVP 1116



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 626 PPGEEDRVYPPPQFIVPLKSVTAMEGGKIH--FETRIE----PVGDPTMKIEWLKNGQSI 679
           P GEEDR++    ++ P       E  K+    +T I       G P  +I WLKNG  +
Sbjct: 362 PAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL 421

Query: 680 EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
             SS    +   G + + ++   + D   YTC A +  GV
Sbjct: 422 PLSSHI-RLLAAGQV-IRIVRAQVSDVAVYTCVASNRAGV 459



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +S   EC  E  P P  R+ W  +G VL   H   +  + GF  L I + +  D+G Y C
Sbjct: 766  KSTVLECIAEGVPTP--RITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 821

Query: 1920 KAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
             A N  G     I L V    SI     + + +  +Q
Sbjct: 822  MATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 858



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G PT +I W K+G  +  +    SI   G++ +   S ++ D+G Y C A +A G    +
Sbjct: 776 GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ--SAHVTDTGRYLCMATNAAGTDRRR 833

Query: 724 AVL--HVTP 730
             L  HV P
Sbjct: 834 IDLQVHVPP 842



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT R+ W  +G  +   H   +  + G+  L I  A+  DTG Y+C ATNA G
Sbjct: 778  PTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 828



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
            A + G S T   LT       PP   +T     ++ENS A   C  +     +  + W  
Sbjct: 1189 ANVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQAILPC--VADGIPTPAINWKK 1242

Query: 3596 NGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   L       T   +G +ILE   V   D+G YTC A N  GE T +  L V
Sbjct: 1243 DNVLLANLLGKYTAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTV 1294



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 3564 PSDL--ILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            PSD+  +L EN         IP    +  ++W  +GKP+ +G   +         L I G
Sbjct: 291  PSDVSVLLGENVELVCNANGIP----TPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 346

Query: 3622 VYQRDAGLYTCKATNRHGE 3640
                D G YTC ATN  GE
Sbjct: 347  ALTSDTGKYTCVATNPAGE 365



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WL+DG+P+   + +T   + G V   +K+ T  D+G YTC A N  G+ +    L ++  
Sbjct: 507  WLRDGQPLGLDAHLTVSTH-GMVLQLLKAET-EDSGKYTCIASNEAGEVSKHFILKVLEP 564

Query: 1005 KDIIAESQH 1013
              I    +H
Sbjct: 565  PHINGSEEH 573



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P      ++ E++      LE T      P  ++ W  +GRP+ Q  + +T    G
Sbjct: 561  VLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--G 618

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGE 2060
               L I  A  EDTG Y C A++  G+
Sbjct: 619  GEVLRISTAQVEDTGRYTCLASSPAGD 645



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 942 RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
           ++ W+KDGRP+  + ++ T    G   L I +  V D G YTC A +  G
Sbjct: 597 KMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAG 644



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P  L++  N S   EC  I     + R+ W  +G  L       +I + GF  
Sbjct: 750  PPNIKGGPQSLVILLNKSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGF-- 805

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I   +  D G Y C ATN  G       LQV
Sbjct: 806  LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 838



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
            T  + W      +  AN +  Y    Y  L + +V  EDSG YT VA NAAGE   + S+
Sbjct: 1235 TPAINW--KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 1292

Query: 1134 TV 1135
            TV
Sbjct: 1293 TV 1294



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   +G+ +   C    +  P  K+ W FNN  +P+   + S +  S   L I    +E
Sbjct: 1306 DVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIPA--HFDSVNGHS--ELVIERVSKE 1359

Query: 2842 DSGIYTCKATNSKGSATTSG 2861
            DSG Y C A NS G     G
Sbjct: 1360 DSGTYVCTAENSVGFVKAIG 1379



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +  G     +C+ TG P P +TW      I  D      VN   N++L I +    D+  
Sbjct: 1489 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSE 1544

Query: 463  VTCVARNKSG 472
              CVARN  G
Sbjct: 1545 FECVARNLMG 1554



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            ++++EG     E     +      + W K+GR +  S+ +    + G + L IK   V D
Sbjct: 107  VNVREGTSVSLEXESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEVSD 162

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
             G Y CRA N  G+   + +L +     I
Sbjct: 163  TGQYVCRAINVAGRDDKNFHLNVYVPPSI 191



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/71 (29%), Positives = 37/71 (52%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  N K+I +++ ++     G   L IA  +  DSG YT +A N  G+AQ    +++
Sbjct: 220  TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 279

Query: 1136 ETRSSIDTSSI 1146
            +   S+  + I
Sbjct: 280  QVPPSVAGAEI 290



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 4/101 (3%)

Query: 1314 SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            S     I  ++G++  + C     G     + W  +G+P+  G           + L LL
Sbjct: 477  SMGTEEITVLKGSSTSMACITD--GTPAPSMAWLRDGQPL--GLDAHLTVSTHGMVLQLL 532

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                EDSG YTC A+N+ GE      L+V+    +    +H
Sbjct: 533  KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH 573



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C  +  P P+  + W+ +G+ +    R R  +     +L I  V   D+G YTC A N  
Sbjct: 1138 CEADGLPPPD--ITWHKDGRAIVESIRQRVLSS---GSLQITFVQPGDAGHYTCMAANVA 1192

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQ 1956
            G + +S +L V     I     H +  E  Q
Sbjct: 1193 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 1223



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E  G P   I W K+G++I  S R   +   G  SL +  +   D+G YTC A +  G +
Sbjct: 1139 EADGLPPPDITWHKDGRAIVESIR-QRVLSSG--SLQITFVQPGDAGHYTCMAANVAGSS 1195

Query: 721  --ETKAVLHVTPRATIERTSQH 740
               TK  +HV PR  I  T  H
Sbjct: 1196 STSTKLTVHVPPR--IRSTEGH 1215



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KD   V  ++ +  +    Y  L +++V + D+G YTC A NA G+ T +
Sbjct: 1232 GIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT 1289

Query: 997  ANLTI 1001
             +LT+
Sbjct: 1290 VSLTV 1294



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            GDP+   +W   GV++++  R R     G  +L I   V  DAG Y C A N AG
Sbjct: 1413 GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAG 1464



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ LE     +  P   + W+ NGR +T  +  +   D     L I  A  +DTG
Sbjct: 109  VREGTSVSLEXESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTG 164

Query: 1249 EYTVRAVNHLG 1259
            +Y  RA+N  G
Sbjct: 165  QYVCRAINVAG 175



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   ++W  +GK +  G   R         L+I      ++G+Y CVATN  G +    N
Sbjct: 312  PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFN 371

Query: 3372 LKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMV 3405
            L      N+ +   + RG +   EKL TL D+ +
Sbjct: 372  L------NVYVTPTI-RGNKDEAEKLMTLVDTSI 398



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 5/85 (5%)

Query: 3694 PPRFT-VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            PP     E  + I V    P+   C     G P  ++ W  +GRP     +V TL   G 
Sbjct: 564  PPHINGSEEHEEISVIVNNPLELTCIAS--GIPAPKMTWMKDGRPLPQTDQVQTLG--GG 619

Query: 3753 IALDIDYIYARDAGEYTCRATNKWG 3777
              L I      D G YTC A++  G
Sbjct: 620  EVLRISTAQVEDTGRYTCLASSPAG 644



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 14/153 (9%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +DI V  N+    E +   V  P   + WLRNG  ++A+ R+  +    Y+ +N   +  
Sbjct: 667  RDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILSGGRYLQINNADLG- 723

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQ-------SKASLQLESQHESALQKIQQLEDSSRY 1830
             D+  YTC A N  G+      L V           SL +     + L+ I +   + R 
Sbjct: 724  -DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRI 782

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAH 1863
              R+D  V      R+    NG   +   QSAH
Sbjct: 783  TWRKDGAVLAGNHARYSILENGFLHI---QSAH 812



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            DPT  ++W + G  I  S RI  +   G  SL I     EDAG YT  A N+ G    + 
Sbjct: 1414 DPTPTIQWNRKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 1470

Query: 859  SIRVAARSTVTAD 871
            S+ + +   +T +
Sbjct: 1471 SLTLQSPPIITLE 1483



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 4/85 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   E      P P   + WY NG+++          D     L I      D+G+Y
Sbjct: 111  EGTSVSLEXESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 166

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C+AIN  G+   +  LNV    SI
Sbjct: 167  VCRAINVAGRDDKNFHLNVYVPPSI 191



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 1/89 (1%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
           VY PP    P + V  +E          +  G P   I WLKN + IE S         G
Sbjct: 185 VYVPPSIEGPEREVI-VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 243

Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              L +      DSG YTC A +  G A+
Sbjct: 244 GSKLQIARSQHSDSGNYTCIASNMEGKAQ 272



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G S    C  +  P P+M   W  +G+ L     + T +  G   L +L    EDSG+Y
Sbjct: 487  KGSSTSMACITDGTPAPSMA--WLRDGQPLGLD-AHLTVSTHGMV-LQLLKAETEDSGKY 542

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
            TC A N  G+      L V     I    +HE
Sbjct: 543  TCIASNEAGEVSKHFILKVLEPPHINGSEEHE 574



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP I   P++  +        +    G P PR+TW K+G  L  +  H   +   +  L 
Sbjct: 750 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLH 807

Query: 325 VRNTQKSDSGHYTLLAENPNG 345
           +++   +D+G Y  +A N  G
Sbjct: 808 IQSAHVTDTGRYLCMATNAAG 828



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   + W+KDGR I  S R   + + G  SL I  ++  DAG YT  A N  G + ++  
Sbjct: 1144 PPPDITWHKDGRAIVESIR-QRVLSSG--SLQITFVQPGDAGHYTCMAANVAGSSSTSTK 1200

Query: 860  IRV 862
            + V
Sbjct: 1201 LTV 1203



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N  L C ++  GDPT  ++W   G  + +  R +     G  +L I    + D G+YT
Sbjct: 1402 GGNAILNCEVK--GDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYT 1456

Query: 1252 VRAVNHLGSAHTS 1264
              A N  G    S
Sbjct: 1457 CVATNEAGVVERS 1469



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E   DPT  I+W  N K +     ++        SL I  T  ED+G YTC ATN  G
Sbjct: 1408 NCEVKGDPTPTIQW--NRKGVDIEISHR-IRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 1464

Query: 2856 SATTSGSL 2863
                S SL
Sbjct: 1465 VVERSMSL 1472



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            DPT  ++W   G  ++  HR +     G  +L I     ED G Y C ATN  G    + 
Sbjct: 1414 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 1470

Query: 2066 SVKVDAKSGLYLDTLD 2081
            S+ + +   + L+ ++
Sbjct: 1471 SLTLQSPPIITLEPVE 1486



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G+     C    I  P   I W  +G+ I +G   R         L+I      D+G Y 
Sbjct: 299  GENVELVCNANGIPTP--LIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 356

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C ATN  GE      L V
Sbjct: 357  CVATNPAGEEDRIFNLNV 374



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            P   I+W K+G  + +G   +        TL+I      D+G YTC ATN  GE
Sbjct: 312  PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 365



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++G  I  S R   +      +L + +V P D+G YTC A N  G + TS
Sbjct: 1142 GLPPPDITWHKDGRAIVESIRQRVLSSG---SLQITFVQPGDAGHYTCMAANVAGSSSTS 1198

Query: 1798 STLFVQSKASLQLESQHESALQKIQQL 1824
            + L V     ++    H +  +  Q +
Sbjct: 1199 TKLTVHVPPRIRSTEGHYTVNENSQAI 1225



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N  PI+ +    T+   G   L +      D G YTC AIN+ GE+   
Sbjct: 28   GFPPPDLSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 85

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAV---NQAPRFITQLNGPT 1854
             +L V    S++       ++  +++    S       V   V    +  R IT+     
Sbjct: 86   FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPVITWYKNGRMITESTHVE 145

Query: 1855 KLSEGQSAH 1863
             L++GQ  H
Sbjct: 146  ILADGQMLH 154



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P   I+W ++GK + SG   R        +L+I      D+G+Y C A N  GE+
Sbjct: 312  PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 366



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSG 1381
            T+  T++++ECR    G    ++ W  NG P+      R       + +    V   D  
Sbjct: 392  TLVDTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SDVA 447

Query: 1382 VYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
            VYTC A+N+ G       L+V A  ++     +  G E+I  L+ +S
Sbjct: 448  VYTCVASNRAGVDNKHYNLQVFAPPNM----DNSMGTEEITVLKGSS 490



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 11/86 (12%)

Query: 2139 PHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            P  ++ W  +GQ +    H   +TH    + L +L    EDSG Y C A+N+ GE     
Sbjct: 501  PAPSMAWLRDGQPLGLDAHLTVSTHG---MVLQLLKAETEDSGKYTCIASNEAGEVSKHF 557

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQL 2223
             LKV       L+  H NG E+  ++
Sbjct: 558  ILKV-------LEPPHINGSEEHEEI 576



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           P   + W +DG+P+   + +T +   G V L ++    ED+G YT  A N+ GE
Sbjct: 501 PAPSMAWLRDGQPLGLDAHLT-VSTHGMV-LQLLKAETEDSGKYTCIASNEAGE 552



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T+E  + + +  GG +  +C+    G+P   I W   G   +   RV+ L++   
Sbjct: 1476 SPPIITLEPVETV-INAGGKIILNCQA--TGEPQPTITWSRQGHSISWDDRVNVLSNNSL 1532

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
               D       D  E+ C A N  GS
Sbjct: 1533 YIADAQ---KEDTSEFECVARNLMGS 1555



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +  +P P++   W  N + ++      T    G   L I+     D GEYTC AIN  
Sbjct: 24   CEVSGFPPPDL--SWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 79

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHES 1950
            G++     L V    S I+D   ES
Sbjct: 80   GESKKKFSLTVYVPPS-IKDHDSES 103



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V +G +  + C  +  G P   + W  +G+ + + +   T    G V L ++ A + D+G
Sbjct: 485  VLKGSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHL-TVSTHGMV-LQLLKAETEDSG 540

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
            +YT  A N  G      I++V+E   I    ++E+
Sbjct: 541  KYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE 575



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 3557 PPEFTTT--PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP    T  P D+ +  N     EC+   V      + W  NG+ L    RV+ ++  G 
Sbjct: 657  PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV--ITWLRNGERLQATPRVRILS--GG 712

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
              L+I      D   YTC A+N  G+ T          +  IL   +P + K G +S+
Sbjct: 713  RYLQINNADLGDTANYTCVASNIAGKTT----------REFILTVNVPPNIKGGPQSL 760



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G P   I W KNG  +        I   G  ++++L+  +  +G YTC A +A G A   
Sbjct: 960  GVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYTCVARNAAGSAHRH 1017

Query: 724  AVLHV 728
              LHV
Sbjct: 1018 VTLHV 1022



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 3/81 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W+ +G+ I  + R Q     G  +L I  V+  D+G YT +A N AG +  S  +TV 
Sbjct: 1148 ITWHKDGRAIVESIR-QRVLSSG--SLQITFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 1204

Query: 1137 TRSSIDTSSIHRGLYEKTRHI 1157
                I ++  H  + E ++ I
Sbjct: 1205 VPPRIRSTEGHYTVNENSQAI 1225



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 14/133 (10%)

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            T   +G ++LE       DSG Y+C A N  G+   +V L     +    P FT  +   
Sbjct: 1255 TAEPYGELILE--NVVLEDSGFYTCVANNAAGEDTHTVSL-----TVHVLPTFT-ELPGD 1306

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
              L  G+     C    +  P  K+ W  N   +       +V+  G   L I      D
Sbjct: 1307 VSLNKGEQLRLSCKATGIPLP--KLTWTFNNNII--PAHFDSVN--GHSELVIERVSKED 1360

Query: 3219 SGEYVCRAYNKYG 3231
            SG YVC A N  G
Sbjct: 1361 SGTYVCTAENSVG 1373



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 14/146 (9%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYVALDLLSVY 1376
            N+  V    + L C +   G     + W  N +PIK  T     P        L ++   
Sbjct: 11   NLTVVVNNFISLTCEVS--GFPPPDLSWLKNEQPIKLNTNTLIVPGGR----TLQIIRAK 64

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              D G YTC A NQ GE+    +L V       ++      L  +   E TS      + 
Sbjct: 65   VSDGGEYTCIAINQAGESKKKFSLTVYVPPS--IKDHDSESLSVVNVREGTS----VSLE 118

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHV 1462
             ES  + P  +T  K+   + E  HV
Sbjct: 119  XESNAVPPPVITWYKNGRMITESTHV 144



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLK+ +P++ ++   T    G   L I    V D G YTC A N  G++    +LT+ 
Sbjct: 34   LSWLKNEQPIKLNTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 91

Query: 1003 TKKDI 1007
                I
Sbjct: 92   VPPSI 96



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/81 (28%), Positives = 35/81 (43%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G PT  I+WLK+G+ I +             +L++      D+G+YTC A +  G  +  
Sbjct: 310 GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI 369

Query: 724 AVLHVTPRATIERTSQHPETL 744
             L+V    TI       E L
Sbjct: 370 FNLNVYVTPTIRGNKDEAEKL 390



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            ++W  + KP+ SG       +     L+I   L  D+G YTC A N  GE
Sbjct: 316  IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 365



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E   I  G P  ++ W+++G P+  ++++ T+   G   L +     ED+G YTC A + 
Sbjct: 585  ELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLG--GGEVLRISTAQVEDTGRYTCLASSP 642

Query: 1791 LGE 1793
             G+
Sbjct: 643  AGD 645



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + WL++G  ++A+ R+       Y  L I +  + D  +YTC A N  G+ T    LT+
Sbjct: 691  ITWLRNGERLQATPRVRILSGGRY--LQINNADLGDTANYTCVASNIAGKTTREFILTV 747



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP      QS   L+  ++T  EC     G P  ++ W  +G  L   +    I + G++
Sbjct: 750  PPNIKGGPQSLVILLN-KSTVLEC--IAEGVPTPRITWRKDGAVLAGNHARYSILENGFL 806

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
             +    V   D+G YLC ATN  G D  +  ++    P I
Sbjct: 807  HIQSAHV--TDTGRYLCMATNAAGTDRRRIDLQVHVPPSI 844



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 12/169 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NG  +       +        L I+     D+ TY C  TN  G  + 
Sbjct: 866  TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKR 925

Query: 3135 SVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +V L   V  S   +P  T  +     +     A   CT   V  P   I W  NG  +R
Sbjct: 926  TVDLTVQVPPSIADEP--TDFL-----VTKHAPAVITCTASGVPFP--SIHWTKNG--IR 974

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
               R           ++I  TQ + +G Y C A N  G      T++ +
Sbjct: 975  LLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVH 1023



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P+D ++++++ A   C    V   S  + W  NG  LL       I   G + 
Sbjct: 934  PPSIADEPTDFLVTKHAPAVITCTASGVPFPS--IHWTKNGIRLLPRGDGYRILSSGAI- 990

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             EI       AG YTC A N  G A     L V   +  +++PQ
Sbjct: 991  -EILATQLNHAGRYTCVARNAAGSAHRHVTLHV--HEPPVIQPQ 1031



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F T L    +L +G++    C+   I  P LT  W  N   I A   + + +  G+  
Sbjct: 1298 PTF-TELPGDVSLNKGEQLRLSCKATGIPLPKLT--WTFNNNIIPA--HFDSVN--GHSE 1350

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L I     EDSGTY+C A N +G
Sbjct: 1351 LVIERVSKEDSGTYVCTAENSVG 1373



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   ++W   G  ++   R R     G   L I  T  ED+G+Y C A N  G    + 
Sbjct: 1414 DPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 1470

Query: 3509 SMKVQGKRNIILE 3521
            S+ +Q    I LE
Sbjct: 1471 SLTLQSPPIITLE 1483



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 1444 PRFVTRPKSIEN--VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V  PKS EN  V+    +   C++      +L   W KN QP+ +      +   G 
Sbjct: 1    PPSVIGPKS-ENLTVVVNNFISLTCEVSGFPPPDLS--WLKNEQPIKLNTNTLIVP--GG 55

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              L II     D G YTC A+N  G  +    LT
Sbjct: 56   RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 89



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 4/73 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V EG  V  +     V  P   I W+ NGR     + V  L D     L I      D
Sbjct: 107  VNVREGTSVSLEXESNAVPPPV--ITWYKNGRMITESTHVEILADGQM--LHIKKAEVSD 162

Query: 3765 AGEYTCRATNKWG 3777
             G+Y CRA N  G
Sbjct: 163  TGQYVCRAINVAG 175



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            ++ W KNG P+ +    R +   G V + I+     D  +YTC A N  G D     L  
Sbjct: 411  QINWLKNGLPLPLSSHIRLLAA-GQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV 468

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             +  ++     N  G E+I VL+  S
Sbjct: 469  FAPPNM----DNSMGTEEITVLKGSS 490



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            G PT RI W  +G   A     +++ + GF  L I   +  D G Y C ATN  G+
Sbjct: 776  GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGT 829



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            I W  +G  +  +H   ++   G   L I     TD+G Y C ATN  G     + L+  
Sbjct: 782  ITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH 839

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            V  S    P   T I N++           C    +  P   I W  NG  +       +
Sbjct: 840  VPPSIAPGPTNMTVIVNVQ-------TTLACEATGIPKP--SINWRKNGHLLNVDQNQNS 890

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                    L I      D+  Y C   N  G+D
Sbjct: 891  YRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 923



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 5/89 (5%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            V   HL   V      I   C  +    P   I W  + + +    R +     S  SL 
Sbjct: 1118 VISPHLKEYVIAVDKPITLSCEADGLPPPD--ITWHKDGRAIVESIRQRV---LSSGSLQ 1172

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            IT     D+G YTC A N  GS++TS  L
Sbjct: 1173 ITFVQPGDAGHYTCMAANVAGSSSTSTKL 1201



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ L    ++ +G+     C+    G P  K+ W  N  +I   +     +  G+  
Sbjct: 1298 PTFTE-LPGDVSLNKGEQLRLSCKA--TGIPLPKLTWTFNNNIIP--AHFDSVN--GHSE 1350

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  V  ED G Y+C A N +G
Sbjct: 1351 LVIERVSKEDSGTYVCTAENSVG 1373



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N++EG +   +     V  P   + W++N ++I +S+ +    D G + + I     
Sbjct: 105  SVVNVREGTSVSLEXESNAVPPPV--ITWYKNGRMITESTHVEILAD-GQM-LHIKKAEV 160

Query: 2444 EDEGVYMCRASNLLG 2458
             D G Y+CRA N+ G
Sbjct: 161  SDTGQYVCRAINVAG 175



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V LE   E    P   I W+KNG  +T    ++   D  +  L I      D+G Y
Sbjct: 111  EGTSVSLEX--ESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAEVSDTGQY 166

Query: 2716 TCKATNLLG 2724
             C+A N+ G
Sbjct: 167  VCRAINVAG 175



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W +N K IE+S  +      G   + I+  +  D G Y C ASN+ G+
Sbjct: 215  GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 270



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G N +      G PTP++ W +   P+       +R +      +L I      D G+YT
Sbjct: 299 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYT 356

Query: 146 CTARNQYGE 154
           C A N  GE
Sbjct: 357 CVATNPAGE 365



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            ++S + ECR         ++ W  NG PL   S ++ +   G VI  I      D  +YT
Sbjct: 395  DTSINIECRA--TGTPPPQINWLKNGLPLPLSSHIRLLAA-GQVI-RIVRAQVSDVAVYT 450

Query: 3632 CKATNRHGEATVSCKLQV 3649
            C A+NR G       LQV
Sbjct: 451  CVASNRAGVDNKHYNLQV 468



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P  ++ W KDGRP+  + ++ ++   G   L I   + ED G YT  A +  G+      
Sbjct: 594 PAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYL 651

Query: 860 IRV 862
           +RV
Sbjct: 652 VRV 654



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)

Query: 1193 KNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYT 1251
            K+  LEC  E  G PT R+ W  +G +V  G+  + +  + GF+ +   H T  DTG Y 
Sbjct: 766  KSTVLECIAE--GVPTPRITWRKDG-AVLAGNHARYSILENGFLHIQSAHVT--DTGRYL 820

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
              A N  G+      ++V     I     N   I  +Q
Sbjct: 821  CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQ 858



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G  A  +C +   GDPT  ++W R    IE S RI      G  S+ I    +ED G Y 
Sbjct: 1402 GGNAILNCEV--KGDPTPTIQWNRKGVDIEISHRI---RQLGNGSLAIYGTVNEDAGDYT 1456

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 1457 CVATNEAG 1464



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 5/100 (5%)

Query: 3829 PPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887
            PP  I  + ++ TV  +  +   C V     P L   W +N +  P      T+   G  
Sbjct: 1    PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDL--SWLKNEQ--PIKLNTNTLIVPGGR 56

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            +L I+     D GEY C A+N  GE   K +++    P I
Sbjct: 57   TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI 96



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/71 (33%), Positives = 31/71 (43%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL+N   IE S+ L      G   L +      DSG YTC A N  G+A   
Sbjct: 215  GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 274

Query: 1798 STLFVQSKASL 1808
              L +Q   S+
Sbjct: 275  YFLSIQVPPSV 285



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
           G  T R+ W KDG  +  +    +    G+  L I+S  V D G Y C A NA G
Sbjct: 776 GVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG 828



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP+  +    +TV E+      C  +    P   I W ++  LL +     T    G
Sbjct: 1203 VHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA--INWKKDNVLLANLLGKYTAEPYG 1260

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             + L+   V  EDSG Y C A N  GED    +++   LP
Sbjct: 1261 ELILE--NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 1298



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            DP   ++W   G  +   HR R   +  + I   +    E++G+Y CVATN+ G
Sbjct: 1414 DPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV---NEDAGDYTCVATNEAG 1464


>AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein
            protein.
          Length = 1232

 Score =  114 bits (275), Expect = 6e-24
 Identities = 157/722 (21%), Positives = 282/722 (39%), Gaps = 63/722 (8%)

Query: 3807 KIKELERGRISDAPKEEPIVST-PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            K   LE   + +      I +T   + +T+ +S TV E E  RF C  + +  P   + W
Sbjct: 346  KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPT--VTW 403

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             R G++L +  R++        + +I  V A D G Y     N  G+   + T++ +K  
Sbjct: 404  LRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 463

Query: 3926 DIILQNQVPRGMKRSEALTQMEATIKK----------YTSEVYLTEDDLYDVDKKQ---- 3971
                    P  +K  E   +    +K           +   V  TE      +K Q    
Sbjct: 464  VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 523

Query: 3972 --PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF- 4028
              PP+    ++++ S    E  K  C +        +V W+ +GK L     F   Y   
Sbjct: 524  SAPPKITQFLKAEAS---KEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 580

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYD-SQLPKHMKSIEKI 4087
            G   +    +   D GE++C  +   G  +T           I    S++ +  KS +K 
Sbjct: 581  GTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 640

Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
             E   + +  P+    E  +  P +   L D  TV     A+F  + TG P+P  +W  +
Sbjct: 641  TESTVTRKTEPK--APEPISSKPVIVTGLQDT-TVSSDSVAKFAVKATGEPRPTAIWTKD 697

Query: 4148 GNTIVNGSRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDY 4206
            G  I  G +YKL+ D G +  +I KT   D+G                  L +    D  
Sbjct: 698  GKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD-- 755

Query: 4207 RGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQ 4266
                           T+ Q+  T  +KT E     Q++ V+  + E+  K ++  E +  
Sbjct: 756  ---------------TEAQKVST--QKTSEITP--QKKAVV--QEEISQKALRSEEIKMS 794

Query: 4267 QSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNL 4326
            ++  ++K        + L +E+V K +    ++ + +I  +++T  + A    + + +  
Sbjct: 795  EAKSQEKLALKEEASKVLISEEVKKSA---ATSLEKSIVHEEITKTSQASEEVRTHAEIK 851

Query: 4327 DQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVG-DKEITRKITST 4385
              + +++    Q+ V  K  I   +++      V +   ++ +  V G D+ +T K  S 
Sbjct: 852  AFSTQMSINEGQRLVL-KANIAGATDAKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASH 910

Query: 4386 ETTEI-EHKAQTQERVVEGPV------KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438
                I    ++T+E +V+         + S  P F  + +   + E +   F  E  GEP
Sbjct: 911  RDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEP 970

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
             P I+W++ N PI  S +  I        L IR   V DS  +   A+N  G    +A+L
Sbjct: 971  SPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 1030

Query: 4499 VV 4500
            +V
Sbjct: 1031 MV 1032



 Score =  100 bits (240), Expect = 1e-19
 Identities = 141/664 (21%), Positives = 262/664 (39%), Gaps = 57/664 (8%)

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +G+SA F C      +P   + W   GQ +  S R +  +       +I+  Q  D G Y
Sbjct: 383  EGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 440

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESL-------QPDSLAKIRE-LESLQGAQQQTP 3274
                 N  G+     T+    K  V  +++        P+   K  E ++S +  +   P
Sbjct: 441  SVVVENSEGKQEAEFTLTIQ-KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEP 499

Query: 3275 STPSAEPPKF-------------ITQIQDVTKLVEGQSAHFEARLVPVDDPDL----KVE 3317
            S P A  P               ++    +T+ ++ +++   A+L  V +  +    +V 
Sbjct: 500  SHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVT 559

Query: 3318 WFYNGKKLP-HGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
            W+ +GKKL  +GH    +   G   L I    E + GE+ C  + + G  ++K NL+   
Sbjct: 560  WYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGG--TSKTNLQFMG 617

Query: 3377 KENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGE 3436
            +    +  ++ +  E      +T E ++ R+ +    E     PV    L +   +    
Sbjct: 618  QAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT-TVSSDS 676

Query: 3437 NAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCR 3496
             A F  + T   +P     W  +GK++  G +++   D G   LEI  T   DSG Y C 
Sbjct: 677  VAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCT 734

Query: 3497 AYNNYGEAVTTASMKVQGKRNIILES-QLPKGMEGTIDKIAALEGYSG-----TVDTLTP 3550
              N+ G   ++  + ++  ++   +     K  E T  K A ++         + +    
Sbjct: 735  VKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS 794

Query: 3551 EAESGNPPEFTTTPSDLILSE----NSSAHFECRLI--PVNDSSMRVEWFHNGKPLLTGS 3604
            EA+S          S +++SE    +++   E  ++   +  +S   E       +   S
Sbjct: 795  EAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS 854

Query: 3605 RVKTINDFGFVILE--IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662
               +IN+   ++L+  I G       L   + TN     +   +  V G    +   Q  
Sbjct: 855  TQMSINEGQRLVLKANIAGATDAKWVLNGVELTN-----SEEYRYGVSGSDQTLTIKQAS 909

Query: 3663 SHFKSGTESIQKLEETLHK-REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEP 3721
               +     I K +E + K + ++T+  E  + P F  + +   ++ EG  V F C +  
Sbjct: 910  HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQ-NINEGQNVLFTCEIS- 967

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
             G+P+  I+WF N  P +  S V         +L+I      D+G+YT +A N  G  + 
Sbjct: 968  -GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSA 1026

Query: 3782 TAKI 3785
            TA +
Sbjct: 1027 TASL 1030



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 145/718 (20%), Positives = 273/718 (38%), Gaps = 57/718 (7%)

Query: 1132 SMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
            S   ETR S+ +         K+  +EE K +E      +I  +    +        V E
Sbjct: 325  SQMTETRESLSSYEHSASAEMKSAALEE-KSLEEKSTTRKIKTTLAARILTKPRSMTVYE 383

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G++    C  +  G+P   V W   G+ ++  +R +          +I    ++D G Y+
Sbjct: 384  GESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYS 441

Query: 1252 VRAVNHLGSAH---TSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVR------ 1302
            V   N  G      T  I +       VT     ++ E      +A +  K+V+      
Sbjct: 442  VVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSH 501

Query: 1303 -----------------EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVE 1345
                             + + V   P+ ++ L    + E     L C ++    +   V 
Sbjct: 502  PKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAK--LTCVVESSVLRAKEVT 559

Query: 1346 WFCNGKPIKTGHRFRPAYEFDYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            W+ +GK +K    F+  Y  D    L + ++   D G + C+ + + G + T+      A
Sbjct: 560  WYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQA 619

Query: 1405 KKDLILESQHPSGLEKIQY--LEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHV 1462
             K +  +    S  +K      E T   K      E ++ KP  VT    +++       
Sbjct: 620  FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVT---GLQDTTVSSDS 676

Query: 1463 HFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAV 1522
              +  ++   +      W K+G+ +T G +++   D G   L+I      DSG+YTC   
Sbjct: 677  VAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK 736

Query: 1523 NLVGTDEVSCRLTCRSTTDIVR---STQNEAGL---EQIQVLEDRS-KYHRTDMV--DEV 1573
            N  G+   SC+LT ++  D      STQ  + +   ++  V E+ S K  R++ +   E 
Sbjct: 737  NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEA 796

Query: 1574 TTQAPI-----CTTSLKNVEIKEGQRAHFERRLI--PVSDATLKVEWYHNNKPLKSGSRF 1626
             +Q  +      +  L + E+K+      E+ ++   ++  +   E    +  +K+ S  
Sbjct: 797  KSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQ 856

Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLES-QHEGAL 1685
               N    + L        D+            E    G++      +I   S + EG L
Sbjct: 857  MSINEGQRLVLKANIAGATDAKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGIL 916

Query: 1686 PRLNQL-EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRV 1744
              +++  E   K Q      + ++ AP F    +   + E Q   F   +   G+P   +
Sbjct: 917  TCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEI--SGEPSPEI 974

Query: 1745 EWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            EW +N +PI  S+ ++        +L ++  +  DSG YT +A N  G+   +++L V
Sbjct: 975  EWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 1032



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 65/267 (24%), Positives = 107/267 (40%), Gaps = 7/267 (2%)

Query: 79  KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
           ++ R   G N +F   ++  PT  V W      L E +K  + Y   +G ++L I     
Sbjct: 190 RSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSK--IHYTNTSGVLTLEILDCHT 247

Query: 139 GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
            D G Y     N  GEA  S Y   +                 V  +V  +   T+ Y  
Sbjct: 248 DDSGTYRAVCTNYKGEA--SDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAV 305

Query: 199 EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDR 258
              ++T ++  ++      +     +T E     E S    +    + E  ++      R
Sbjct: 306 SSFKKTSEMEASSSVREVKSQ--MTETRESLSSYEHSASAEMKSAALEEKSLE-EKSTTR 362

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
            +      +I  KPR+  + EG  A+F     G P P VTW + GQ L  S +H++ TT 
Sbjct: 363 KIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK 422

Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +T  + + Q SD G+Y+++ EN  G
Sbjct: 423 YKSTFEISSVQASDEGNYSVVVENSEG 449



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 155/764 (20%), Positives = 275/764 (35%), Gaps = 64/764 (8%)

Query: 4058 ETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLP 4117
            E K+ +  T +    Y+      MKS   + E     + T  ++     AR     ++ P
Sbjct: 322  EVKSQMTETRESLSSYEHSASAEMKSAA-LEEKSLEEKSTTRKIKTTLAAR----ILTKP 376

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYD 4176
             ++TV EGE ARF C   G P P V WL  G  +   +R+++T       F+I   +  D
Sbjct: 377  RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASD 436

Query: 4177 TGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFE 4236
             G   V+             L +       + V  + PR    E         +  K  +
Sbjct: 437  EGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVT-SPPRVKSPEPRVKSPEAVKSPKRVK 495

Query: 4237 ERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLR 4296
              +         H   + P   K   TE  Q +      +    L+   ++++ K + + 
Sbjct: 496  SPEP-------SHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVV 548

Query: 4297 ESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVH 4356
            ES+    +   +VT     K + +        + + T +     +T+  +     E +  
Sbjct: 549  ESS---VLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGE 605

Query: 4357 G--KEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE--GPVKPSKPPI 4412
            G   + ++    Q  K +    E   KI+ T+ ++ +    T  R  E   P   S  P+
Sbjct: 606  GGTSKTNLQFMGQAFKSI---HEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV 662

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
                +Q   V     A+F V+  GEP P   W ++   I     +++        L I +
Sbjct: 663  IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 722

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
                DS ++    +N                      G V  S  LT + +  T  Q   
Sbjct: 723  TDTSDSGLYTCTVKNSA--------------------GSVSSSCKLTIKAIKDTEAQ--- 759

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD--SGKYECVAIN 4590
               KV+  K  ++   K    VQ +I  K L  +    + + EA  Q+  + K E   + 
Sbjct: 760  ---KVSTQKTSEITPQKKAV-VQEEISQKALRSE---EIKMSEAKSQEKLALKEEASKVL 812

Query: 4591 SAGEARCDAECVVSLPATKD---KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
             + E +  A   +      +   K    ++      EI        + EGQ +     I 
Sbjct: 813  ISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIA 872

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G      +W      +  S+ ++   +  + TL I +A   DEG   C++    G   V 
Sbjct: 873  GAT--DAKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEG--IVK 928

Query: 4708 AKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
             +  +T   +  + PA ++  R   + EGQ   F  +I+ +  P I+W +    I  + +
Sbjct: 929  CQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN 988

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
              +    N   L I N    D+G +T +A    GQ   +A L+V
Sbjct: 989  VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 1032



 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 96/434 (22%), Positives = 181/434 (41%), Gaps = 40/434 (9%)

Query: 1005 KDIIAESQHPGGLE-KIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF 1063
            ++ ++  +H    E K   LE+ S   K T  ++K T   R L   +    + EG+SA F
Sbjct: 331  RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMT-VYEGESARF 389

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNA 1123
                +   +   TV W   G+ ++++ R Q          +I+SV+A D G Y+VV  N+
Sbjct: 390  SC--DTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 447

Query: 1124 AGEAQLSASMTVE----TRSSIDTSSIHRGLYEKTRHIE------ESKFVEPMY-QIEEI 1172
             G+ +   ++T++    T  ++ +    +    + +  E        K  EP + +    
Sbjct: 448  EGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSP 507

Query: 1173 SKSKPVFVQ-----PLSNPPPVSE------GKNI-HLECRLEPMGDPTMRVEWFHNGRSV 1220
            +++KP   +     P+S PP +++       K I  L C +E        V W+ +G+ +
Sbjct: 508  TETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL 567

Query: 1221 TVGSRFKTYYDF-GFVALDIIHATSADTGEYTVRAVNHLGSAHTS------AIVRVIERS 1273
                 F+ +Y   G   L I + T +D GE+        G++ T+      A   + E+ 
Sbjct: 568  KENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQAFKSIHEKV 627

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
              +++T+        +  E    R  + +    +   P     L +  TV   +V  +  
Sbjct: 628  SKISETKKSDQ----KTTESTVTRKTEPKAPEPISSKPVIVTGLQD-TTVSSDSV-AKFA 681

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            ++  G+      W  +GK I  G +++ + +     L++      DSG+YTC   N  G 
Sbjct: 682  VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGS 741

Query: 1394 AVTSCALRVIAKKD 1407
              +SC L + A KD
Sbjct: 742  VSSSCKLTIKAIKD 755



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 140/682 (20%), Positives = 249/682 (36%), Gaps = 52/682 (7%)

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            +A + + +  ++ V EGE    +    G P P +TW + G  +  +   ++ T    ST 
Sbjct: 368  LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF 427

Query: 549  DIPRAKASDAAWYQCTAQNVAGS-----TATRARLYXXXXXXXXXXQKRLHLPR---PTK 600
            +I   +ASD   Y    +N  G      T T  +            + +   PR   P  
Sbjct: 428  EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 487

Query: 601  VXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYP---PPQFIVPLKSVTAMEGGKIHFE 657
            V            + + V        P E+ +  P   PP+    LK+  + E  K+   
Sbjct: 488  VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKL--T 545

Query: 658  TRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSA 716
              +E       ++ W K+G+ ++ +  F   +   G   L + +L   D GE+ C     
Sbjct: 546  CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGE 605

Query: 717  TGVAETKAVLHVTPRATI-ERTSQHPETLQYIQQLEDYSKYQHQE-SIEEQTSQRPQFIR 774
             G ++T          +I E+ S+  ET +  Q+  + +  +  E    E  S +P  + 
Sbjct: 606  GGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVT 665

Query: 775  PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMH 834
             LQD   +     A F  + T    PT    W KDG+ IT   +     + G   L I  
Sbjct: 666  GLQDT-TVSSDSVAKFAVKATGEPRPT--AIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 722

Query: 835  LRAEDAGSYTVRAVNKLGEAISTASIRV-AARSTVTADLGIPEQRRYIEKTXXXXXXXXX 893
                D+G YT    N  G   S+  + + A + T    +   +      +          
Sbjct: 723  TDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEIS 782

Query: 894  XXXXXXXXVPESTQKPEFKTPIKDQIS-------IKEGGFAHFEARL--EPIGDSTLRVE 944
                    +  S  K + K  +K++ S       +K+      E  +  E I  ++   E
Sbjct: 783  QKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASE 842

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG------HYTCRAYNAIGQATTSAN 998
             ++    ++A S   +      + L        DA         T       G + +   
Sbjct: 843  EVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDAKWVLNGVELTNSEEYRYGVSGSDQT 902

Query: 999  LTI--VTKKD---IIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTN 1053
            LTI   + +D   +   S+   G+ K QY  D +  SK   +      +PR       + 
Sbjct: 903  LTIKQASHRDEGILTCISKTKEGIVKCQY--DLT-LSKELSDAPAFISQPR-------SQ 952

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
             I EGQ+  F   +    + +  +EW+ N   I+ ++ +         +L+I +    DS
Sbjct: 953  NINEGQNVLFTCEI--SGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 1010

Query: 1114 GVYTVVARNAAGEAQLSASMTV 1135
            G YT+ A+N  G+   +AS+ V
Sbjct: 1011 GKYTIKAKNFRGQCSATASLMV 1032



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 98/428 (22%), Positives = 170/428 (39%), Gaps = 35/428 (8%)

Query: 1803 QSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSA 1862
            +++ SL       SA  K   LE+ S  ++    ++    A R +T+    T + EG+SA
Sbjct: 329  ETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMT-VYEGESA 387

Query: 1863 HYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAI 1922
             + C  +  P P   V W   G+VL +  R++ +     +  +I +V   D G Y+    
Sbjct: 388  RFSCDTDGEPVPT--VTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVE 445

Query: 1923 NNLGQAVSSIRLNVQSKE-------SIIRDSQHESALEKIQYLEDDSRYK-------RAV 1968
            N+ G+  +   L +Q          S  R    E  ++  + ++   R K       +AV
Sbjct: 446  NSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAV 505

Query: 1969 ---QDDSFVVEKPQF---GKPIKNAEVTEGHPVHLEATLTPVNDPTM----RVEWYCNGR 2018
               +      EK Q      P K  +  +       A LT V + ++     V WY +G+
Sbjct: 506  SPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGK 565

Query: 2019 PVQQGHRFKTTYDF-GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLY- 2076
             +++   F+  Y   G   L I      D G ++C+ +   G + T       A   ++ 
Sbjct: 566  KLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQAFKSIHE 625

Query: 2077 -LDTLDEQRL--KKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRV 2133
             +  + E +   +K  E     + +P   E    +PV +T L     +     A F   V
Sbjct: 626  KVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT-TVSSDSVAKFA--V 682

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            +   +P  T  W  +G+ I  G +Y+ + D G   L+I  T   DSG Y C   N  G  
Sbjct: 683  KATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSV 742

Query: 2194 VNTCTLKV 2201
             ++C L +
Sbjct: 743  SSSCKLTI 750



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 106/510 (20%), Positives = 194/510 (38%), Gaps = 35/510 (6%)

Query: 4309 VTSNTVAKSMAQRYEDNLDQT--EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQK 4366
            VT        +QR ++ + ++   E+T        + K      + S+V   +  + + +
Sbjct: 272  VTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETR 331

Query: 4367 QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHE 4426
            ++            K  + E   +E K+ T++      +K +       K +   V+E E
Sbjct: 332  ESLSSYEHSASAEMKSAALEEKSLEEKSTTRK------IKTTLAARILTKPRSMTVYEGE 385

Query: 4427 QARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAE 4486
             ARF  + DGEP+P + W R+   +  S   Q+ T   KS   I  V   D   ++ V E
Sbjct: 386  SARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVE 445

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            N  G  +    L +++ R   +    PP   + +    V S + V+   +V   +P    
Sbjct: 446  NSEGKQEAEFTLTIQKARVTEKAVTSPP--RVKSPEPRVKSPEAVKSPKRVKSPEPSHPK 503

Query: 4547 WLKNGKKVQPDIRNKI----LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             + +  + +P    K+    +      T  +     ++  K  CV  +S   A+   E  
Sbjct: 504  AV-SPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK---EVT 559

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
                  K K     +   +     E LK   + E    E  C+I G+         G   
Sbjct: 560  WYKDGKKLKENGHFQFHYSADGTYE-LKINNLTESDQGEHVCEISGE--------GGTSK 610

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
                   Q  ++  E   +ISE    D+         +   VT   + K  +P  +  + 
Sbjct: 611  TNLQFMGQAFKSIHEKVSKISETKKSDQ-------KTTESTVTRKTEPKAPEPISSKPV- 662

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782
             +T L+D  V     A+F  + T + +PT  W ++G  I +   +++  +     L I  
Sbjct: 663  IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 722

Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            T   D+G +TC    +AG V +S KL +K+
Sbjct: 723  TDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 752



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 137/665 (20%), Positives = 250/665 (37%), Gaps = 59/665 (8%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
            EG +A F        +P   V W + G+ ++ S+R          +  I  ++A D G+Y
Sbjct: 383  EGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 440

Query: 844  TVRAVNKLG--EAISTASIRVA--ARSTVTADLGI--PEQRRYIEKTXXXXXXXXXXXXX 897
            +V   N  G  EA  T +I+ A      VT+   +  PE R    +              
Sbjct: 441  SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPS 500

Query: 898  XXXXVPESTQKPEFKTPIKD-QISI--KEGGFAHFEARLE------PIGDSTLR---VEW 945
                V  +  KP     ++   +S   K   F   EA  E       +  S LR   V W
Sbjct: 501  HPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTW 560

Query: 946  LKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
             KDG+ ++ +      ++  G   L I ++T  D G + C      G + T+        
Sbjct: 561  YKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQAF 620

Query: 1005 KDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVK--ITQKPRFLGPLKGTNKIVEGQSAH 1062
            K I  +       +K       S  +++TE +    I+ KP  +  L+ T  +     A 
Sbjct: 621  KSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSSDSVAK 679

Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            F   V+   +   T  W  +GK IT   + +   D G   L+I      DSG+YT   +N
Sbjct: 680  FA--VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKN 737

Query: 1123 AAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQI-EEISKSKPVFVQ 1181
            +AG    S  +T++     +   +     +KT  I   K      +I ++  +S+ + + 
Sbjct: 738  SAGSVSSSCKLTIKAIKDTEAQKVST---QKTSEITPQKKAVVQEEISQKALRSEEIKMS 794

Query: 1182 PLSNPPPVS---EGKNIHLECRLEPMGDPTMRVEWFHNGRSVT--VGSRFKTYYDFGFVA 1236
               +   ++   E   + +   ++     ++     H   + T       +T+ +    +
Sbjct: 795  EAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS 854

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
              +    S + G+  V   N  G+     ++  +E ++           +Q   ++ A+ 
Sbjct: 855  TQM----SINEGQRLVLKANIAGATDAKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASH 910

Query: 1297 R----------TKQ----VREDITVMQ----APQFSRALHNIETVEGTNVHLECRLQPVG 1338
            R          TK+     + D+T+ +    AP F     +    EG NV   C +   G
Sbjct: 911  RDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEIS--G 968

Query: 1339 DQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSC 1398
            + +  +EWF N  PI        +   +  +L++ +    DSG YT +A N  G+   + 
Sbjct: 969  EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 1028

Query: 1399 ALRVI 1403
            +L V+
Sbjct: 1029 SLMVL 1033



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 150/731 (20%), Positives = 277/731 (37%), Gaps = 78/731 (10%)

Query: 1529 EVSCRLTCRSTTDIVRSTQNEAGLE-QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNV 1587
            EV  ++T   T + + S ++ A  E +   LE++S   ++      TT A    T  +++
Sbjct: 322  EVKSQMT--ETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSM 379

Query: 1588 EIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDS 1647
             + EG+ A F        +    V W    + L + +R   T        +I S    D 
Sbjct: 380  TVYEGESARFS--CDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDE 437

Query: 1648 GTYTCRAINALGEAVTSGIAIVH----SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQ 1703
            G Y+    N+ G+        +     ++K++    + +   PR+   E     +R  + 
Sbjct: 438  GNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSP 497

Query: 1704 D-----------------EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKL---- 1742
            +                 E +   PV + P K  +  + +A+   A+L  V +  +    
Sbjct: 498  EPSHPKAVSPTETKPTPTEKVQHLPV-SAPPKITQFLKAEASKEIAKLTCVVESSVLRAK 556

Query: 1743 RVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
             V W ++G  ++ +      +   G   L +  +   D G + C    E G + T+    
Sbjct: 557  EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFM 616

Query: 1802 VQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVA--VNQAPRFITQLNGPTKLSEG 1859
             Q+  S+  +    S  +K  Q    S   R+ + +    ++  P  +T L   T +S  
Sbjct: 617  GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSSD 675

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
              A +  +    P P     W  +GK +  G +Y+ S D G   L+I      DSG YTC
Sbjct: 676  SVAKFAVKATGEPRPT--AIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 733

Query: 1920 KAINNLGQAVSSIRLNVQS--------------------KESIIRDSQHESAL--EKIQY 1957
               N+ G   SS +L +++                    K++++++   + AL  E+I+ 
Sbjct: 734  TVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKM 793

Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVT--EGHPVHLEATLTPVNDPTMR----V 2011
             E  S+ K A+++++    K    + +K +  T  E   VH E T T      +R    +
Sbjct: 794  SEAKSQEKLALKEEA---SKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEI 850

Query: 2012 EWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
            + +     + +G R     +    A D  +      G  +   +      V+ S   +  
Sbjct: 851  KAFSTQMSINEGQRLVLKANIA-GATDAKWVL---NGVELTN-SEEYRYGVSGSDQTLTI 905

Query: 2072 KSGLYLDTLDEQRLKKIQE-LEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFE 2130
            K   + D      + K +E + K +    + +E     P F++   S +N+ EG    F 
Sbjct: 906  KQASHRDEGILTCISKTKEGIVKCQYDLTLSKEL-SDAPAFISQPRS-QNINEGQNVLFT 963

Query: 2131 CRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKL 2190
            C +    +P   I+WF N   I        +      +L+I      DSG Y  KA N  
Sbjct: 964  CEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFR 1021

Query: 2191 GEAVNTCTLKV 2201
            G+   T +L V
Sbjct: 1022 GQCSATASLMV 1032



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 107/486 (22%), Positives = 187/486 (38%), Gaps = 39/486 (8%)

Query: 3534 KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEW 3593
            K AALE  S    + T + ++       T P  + + E  SA F C      +    V W
Sbjct: 346  KSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTD--GEPVPTVTW 403

Query: 3594 FHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV-KGR 3652
               G+ L T +R +          EI  V   D G Y+    N  G+      L + K R
Sbjct: 404  LRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 463

Query: 3653 ---QGIILEPQL--PSHFKSGTESIQ-----KLEETLHKREEITIEDEKPNP-------- 3694
               + +   P++  P       E+++     K  E  H +  ++  + KP P        
Sbjct: 464  VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKA-VSPTETKPTPTEKVQHLP 522

Query: 3695 ----PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLN 3748
                P+ T  +K              C VE        + W+ +G+        + H   
Sbjct: 523  VSAPPKITQFLKAEASKEIA---KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSA 579

Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE-SQLPQGM-SGE 3806
            D G   L I+ +   D GE+ C  + + G++ T  +    A + I  + S++ +   S +
Sbjct: 580  D-GTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQ 638

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866
            K  E    R ++    EPI S+ P  +T ++  TV      +F   V+   +P+    W 
Sbjct: 639  KTTESTVTRKTEPKAPEPI-SSKPVIVTGLQDTTVSSDSVAKFA--VKATGEPRPTAIWT 695

Query: 3867 RNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
            ++GK +  G +Y+   D G   L+I      DSG Y C   N  G   +   ++ K + D
Sbjct: 696  KDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 755

Query: 3927 IILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLV 3986
               + Q     K SE   Q +A +++  S+  L  +++   + K   +   + ++   L+
Sbjct: 756  --TEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLI 813

Query: 3987 EMETTK 3992
              E  K
Sbjct: 814  SEEVKK 819



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 94/417 (22%), Positives = 164/417 (39%), Gaps = 45/417 (10%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            S P+     ++   +    AKF  K  G P P   WT+    + +  KY +  +E  G  
Sbjct: 659  SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL--SEDKGGF 716

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
             L I +    D G YTCT +N  G    S  +  +               +  SE    K
Sbjct: 717  FLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVST---QKTSEITPQK 773

Query: 190  AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREV--SFRESITKRYVGE 247
                Q   ++++ +++++  +           K +  +  +  EV  S   S+ K  V E
Sbjct: 774  KAVVQEEISQKALRSEEIKMSEAKSQEKLA-LKEEASKVLISEEVKKSAATSLEKSIVHE 832

Query: 248  SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307
               +I+     S    +  +I        + EG     +  ++G    +  W  NG  L 
Sbjct: 833  ---EITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDAK--WVLNGVELT 887

Query: 308  NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
            NS ++    + +  TL ++     D G  T        CI         S T+  +   +
Sbjct: 888  NSEEYRYGVSGSDQTLTIKQASHRDEGILT--------CI---------SKTKEGIV--K 928

Query: 368  SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
             QY     +       E+S+   AP F+   + +++ EG+   F C ++G P PE+ WF 
Sbjct: 929  CQYDLTLSK-------ELSD---APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK 978

Query: 428  NDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            N+  I    N  + ++ S N ++L I N ++SDSG  T  A+N  G+ +    L V+
Sbjct: 979  NNLPISISSN--VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 1033



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 100/479 (20%), Positives = 194/479 (40%), Gaps = 41/479 (8%)

Query: 2243 RFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSL 2302
            R +T+ R  T V+EG++A F C  +   +P   + +   G+ L ++AR  +T      + 
Sbjct: 371  RILTKPRSMT-VYEGESARFSCDTDG--EPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF 427

Query: 2303 DIQHCVPEDAGEYSVKAINALGHCTSAISMT----------VTAKGSIISESQR---PEG 2349
            +I      D G YSV   N+ G   +  ++T          VT+   + S   R   PE 
Sbjct: 428  EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 487

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQN--------IDNIQEGQTAHFDCRLI 2401
            ++  + ++S EP   P+   P T  +P  T+ +Q+        I    + + +    +L 
Sbjct: 488  VKSPKRVKSPEP-SHPKAVSP-TETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLT 545

Query: 2402 PVGDPTL----KVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNL 2456
             V + ++    +V W+++ K ++++      +   G   + I+++ + D+G ++C  S  
Sbjct: 546  CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGE 605

Query: 2457 LGEXXXXXXXXXXXXXXIQLETQH-PEGMKKIQKLEQPHERRSEEPDREFEKPIFTQ--V 2513
             G               I  +     E  K  QK  +    R  EP  +  +PI ++  +
Sbjct: 606  GGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP--KAPEPISSKPVI 663

Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSV 2573
            +TG  +      +  +  V   G+P     W  +G  +  G +++ + D G   L+I+  
Sbjct: 664  VTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKT 723

Query: 2574 VANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMF 2633
              +D+GLY C   N AG                  Q +  +   +I  ++ A+  V E  
Sbjct: 724  DTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAV--VQEEI 781

Query: 2634 VDTGVQQAPIFTTHLKSYDKLV---EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA 2689
                ++   I  +  KS +KL    E   V +  +V+     +L+       +T T+ A
Sbjct: 782  SQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQA 840



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 55/208 (26%), Positives = 91/208 (43%), Gaps = 11/208 (5%)

Query: 371  ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430
            IT T Q   E R     KA + Q         + EG+       + G    +  W +N  
Sbjct: 834  ITKTSQASEEVRTHAEIKAFSTQM-------SINEGQRLVLKANIAGAT--DAKWVLNGV 884

Query: 431  QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490
            ++ +   ++  V+ S +  L I   +  D G++TC+++ K G    Q  L  + KE   A
Sbjct: 885  ELTNSEEYRYGVSGS-DQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDA 942

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P F+ +  + N+ EG+ V+      G P+P I W K+ +PI  +  + I       +L+I
Sbjct: 943  PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 1002

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A  SD+  Y   A+N  G  +  A L
Sbjct: 1003 RNASVSDSGKYTIKAKNFRGQCSATASL 1030



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 79/316 (25%), Positives = 131/316 (41%), Gaps = 17/316 (5%)

Query: 179 YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE 238
           Y  V E  E K       T +++R T+K A T+     S +         +  + V   E
Sbjct: 440 YSVVVENSEGKQEAEFTLTIQKARVTEK-AVTSPPRVKSPEPRVKSPEAVKSPKRVKSPE 498

Query: 239 SITKRYVGESDVQIS-TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
               + V  ++ + + TE  + L   +PPKI Q  +    +E A     V+ S      V
Sbjct: 499 PSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEV 558

Query: 298 TWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVT------- 349
           TW+K+G++L  +   +   + + T  L++ N  +SD G +        G   T       
Sbjct: 559 TWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQ 618

Query: 350 ---SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
              S +  V   +E+   DQ++   T T++ E +    IS K   P  V   QD  V+  
Sbjct: 619 AFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSK---PVIVTGLQDTTVSSD 675

Query: 407 KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
            + +F  + TG P P   W  + + I     +K L  + G   L I     SDSG+ TC 
Sbjct: 676 SVAKFAVKATGEPRPTAIWTKDGKAITQGGKYK-LSEDKGGFFLEIHKTDTSDSGLYTCT 734

Query: 467 ARNKSGETAFQCRLNV 482
            +N +G  +  C+L +
Sbjct: 735 VKNSAGSVSSSCKLTI 750



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 109/510 (21%), Positives = 197/510 (38%), Gaps = 51/510 (10%)

Query: 1374 SVYPE--DSGVYTCQATNQLGEAVTSCALRVIAK-----KDLILESQHPSGLE-KIQYLE 1425
            SV+PE   +  Y   +  +  E   S ++R +       ++ +   +H +  E K   LE
Sbjct: 292  SVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALE 351

Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKN 1483
            + S  +K+       T+  R +T+P+S+  V EG+   F C    EPV      V W + 
Sbjct: 352  EKSLEEKSTTRKIKTTLAARILTKPRSM-TVYEGESARFSCDTDGEPVPT----VTWLRK 406

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS-------CRLTC 1536
            GQ ++   R +          +I  + A D G Y+    N  G  E          R+T 
Sbjct: 407  GQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTE 466

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTD----MVDEVTTQAPICTTSLKNV----- 1587
            ++ T   R    E  ++  + ++   +    +         T   P  T  ++++     
Sbjct: 467  KAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAP 526

Query: 1588 -EIKEGQRAHFERRLIP----VSDATLK---VEWYHNNKPLKSGSRFT-ETNNFGFVALD 1638
             +I +  +A   + +      V  + L+   V WY + K LK    F    +  G   L 
Sbjct: 527  PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 586

Query: 1639 IMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQ--LEDTSK 1696
            I +    D G + C      G + T+   +  + KSI+ +        + +Q   E T  
Sbjct: 587  INNLTESDQGEHVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 646

Query: 1697 YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
             +      E I+  PV    ++D  V+ +  A F  +    G+P+    W ++G  I   
Sbjct: 647  RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKA--TGEPRPTAIWTKDGKAITQG 704

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-------KASLQ 1809
             +     D G   L +   +  DSG YTC   N  G   +S  L +++       K S Q
Sbjct: 705  GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 764

Query: 1810 LESQHESALQKIQQLEDSSRYQRREDVEVA 1839
              S+     + + Q E S +  R E+++++
Sbjct: 765  KTSEITPQKKAVVQEEISQKALRSEEIKMS 794



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 67/284 (23%), Positives = 117/284 (41%), Gaps = 17/284 (5%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F    ++    +G N  F  ++ G P+P + W +   P+   +  S+  +      SL
Sbjct: 943  PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV--YSL 1000

Query: 132  LIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
             I+     D G+YT  A+N  G+  A  S+ + P                R   +T    
Sbjct: 1001 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLP-----LVEEPSREVVLRTSGDTSLQG 1055

Query: 190  AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREV--SFRESITKRYVGE 247
            ++ +Q      S+Q    +  + +  SS  + K  +   + +  +  SF E  +  ++G 
Sbjct: 1056 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 1115

Query: 248  SDV-QISTEIDRSLGPVS---PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
            S++ Q+ +   + L       PPKI   P +  + EG         +G P P VTW   G
Sbjct: 1116 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 1175

Query: 304  QRLIN--SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            +++ +    +  I  T + TTL + + QK D G YTL   N  G
Sbjct: 1176 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 1219



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 82/384 (21%), Positives = 154/384 (40%), Gaps = 28/384 (7%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG++  F C+ +    PT  + W    + L +  R++ T      + +I+     D G Y
Sbjct: 383  EGESARFSCDTDGEPVPT--VTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 440

Query: 2847 TCKATNSKGSATTSGSLRC----TGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPS 2902
            +    NS+G      +L        +K +    +    +  +++ E  +  +  K   PS
Sbjct: 441  SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPS 500

Query: 2903 VPDTEYP---KP---EWI--IPIAAEHQLVE-------GQVLHLEGQVEPKNDPDLKIEW 2947
             P    P   KP   E +  +P++A  ++ +        ++  L   VE       ++ W
Sbjct: 501  HPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTW 560

Query: 2948 YFNGKVLEQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            Y +GK L++   F+   S  G   L + ++ E D G + C+   + G + T+      + 
Sbjct: 561  YKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQAF 620

Query: 3007 DNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIA 3066
             ++ E+      T+  ++        RK   + P+  + +P    T  +D   +S   +A
Sbjct: 621  KSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV-IVTGLQDTT-VSSDSVA 678

Query: 3067 HYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRAT 3126
             +      TG+      W  +GK I    + +     G   LEI  T T+DSG Y+C   
Sbjct: 679  KFAVKA--TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK 736

Query: 3127 NKWGQAEISVKL--ECVDKSKGQK 3148
            N  G    S KL  + +  ++ QK
Sbjct: 737  NSAGSVSSSCKLTIKAIKDTEAQK 760



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 81/376 (21%), Positives = 142/376 (37%), Gaps = 33/376 (8%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + EG++A F C     G+P   V W R  +++  S+R   T      +  IS V+  DEG
Sbjct: 381  VYEGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEG 438

Query: 2448 VYMCRASNLLGEXXXXXXXXXXXXXXIQL-------------ETQHPEGMKKIQKLEQPH 2494
             Y     N  G+               +                + PE +K  ++++ P 
Sbjct: 439  NYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPE 498

Query: 2495 ERRSEEPDREFEKPIFTQVL-----TGPSELWEGQHAHYE---ARVVPVGDPSL----RF 2542
                +       KP  T+ +     + P ++ +   A      A++  V + S+      
Sbjct: 499  PSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEV 558

Query: 2543 EWYINGVELKMGSRFRTTHDF-GFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXX 2601
             WY +G +LK    F+  +   G   L IN++  +D G ++C+     G           
Sbjct: 559  TWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQ 618

Query: 2602 XXXXIIDQAMRPESWEQIQLK--EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQH 2659
                I ++  +    ++   K  E+ + +  E      +   P+  T L+  D  V    
Sbjct: 619  AFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQ--DTTVSSDS 676

Query: 2660 VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKA 2719
            V   A V+   +P     W K+G  +T G + K + D G   L I+     DSG+YTC  
Sbjct: 677  VAKFA-VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTV 735

Query: 2720 TNLLGEAVSTASIKIE 2735
             N  G   S+  + I+
Sbjct: 736  KNSAGSVSSSCKLTIK 751



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 46/174 (26%), Positives = 87/174 (50%), Gaps = 9/174 (5%)

Query: 235 SFRESITKRYVGESDVQISTE--IDRSLGPVSPPKIAQKP------RNSKLQEGADAQFQ 286
           S  E ++K    +   Q +TE  + R   P +P  I+ KP      +++ +   + A+F 
Sbjct: 622 SIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFA 681

Query: 287 VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC 346
           V+ +G PRP   W K+G+ +    K+++        L +  T  SDSG YT   +N  G 
Sbjct: 682 VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGS 741

Query: 347 IVTSGYLAVESPTESYVQDQRSQYITD-TQQRETEERIEISEKALAPQFVKVCQ 399
           + +S  L +++  ++  Q   +Q  ++ T Q++   + EIS+KAL  + +K+ +
Sbjct: 742 VSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSE 795



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 61/306 (19%), Positives = 127/306 (41%), Gaps = 17/306 (5%)

Query: 4308 KVTSNTVAKSMAQRYEDNLDQTEEVTEQR---VQKKVTQKPRIPDPSESTVHGKEVHVAK 4364
            K+T   +  + AQ+   +  +T E+T Q+   VQ++++QK    +  + +    +  +A 
Sbjct: 747  KLTIKAIKDTEAQKV--STQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLAL 804

Query: 4365 QKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFE 4424
            +++  K ++ ++      TS E + +  +     +  E     ++   F+ +M    + E
Sbjct: 805  KEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMS---INE 861

Query: 4425 HEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484
             ++   +    G      KW      + NS +++     +   L I+Q    D  +   +
Sbjct: 862  GQRLVLKANIAGATDA--KWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCI 919

Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
            ++ + G  KC  +L + ++          P+F    ++ N+  GQ V    +++G    +
Sbjct: 920  SKTKEGIVKCQYDLTLSKELSDA------PAFISQPRSQNINEGQNVLFTCEISGEPSPE 973

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            + W KN   +       I      Y+L I  A   DSGKY   A N  G+    A  +V 
Sbjct: 974  IEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV- 1032

Query: 4605 LPATKD 4610
            LP  ++
Sbjct: 1033 LPLVEE 1038



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 91/390 (23%), Positives = 148/390 (37%), Gaps = 31/390 (7%)

Query: 3283 KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVIL 3342
            + +T+ + +T + EG+SA F        +P   V W   G+ L    R++          
Sbjct: 371  RILTKPRSMT-VYEGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF 427

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANL---KCTSKENLILDSQLPRGMEGGLEKLQT 3399
            +I      + G Y  V  N  G+   +  L   K    E  +      +  E  ++  + 
Sbjct: 428  EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEA 487

Query: 3400 LEDSMVRRKDTSVEEEKGKAPVFT----------VPLS---NIENLREGENAHFEARLTP 3446
            ++ S  R K       K  +P  T          +P+S    I    + E +   A+LT 
Sbjct: 488  VK-SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTC 546

Query: 3447 TDDPNL----KVEWYWNGKSLKAGSRFRT-FCDFGFVILEISPTYPEDSGEYLCRAYNNY 3501
              + ++    +V WY +GK LK    F+  +   G   L+I+     D GE++C      
Sbjct: 547  VVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEG 606

Query: 3502 GEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIAALEGYSGTVDTLTPEAESGNPPEF 3560
            G + T      Q  ++I    ++ K  E    D+       +   +   PE  S  P   
Sbjct: 607  GTSKTNLQFMGQAFKSI--HEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPV-I 663

Query: 3561 TTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIG 3620
             T   D  +S +S A F  +     +      W  +GK +  G + K   D G   LEI 
Sbjct: 664  VTGLQDTTVSSDSVAKFAVKA--TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIH 721

Query: 3621 GVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
                 D+GLYTC   N  G  + SCKL +K
Sbjct: 722  KTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 751



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 6/136 (4%)

Query: 232  REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG 291
            R+      I+K   G    Q    + + L     P    +PR+  + EG +  F  ++SG
Sbjct: 911  RDEGILTCISKTKEGIVKCQYDLTLSKELSDA--PAFISQPRSQNINEGQNVLFTCEISG 968

Query: 292  NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG-CIVTS 350
             P P + WFKN   +  S+   I  + N  +L +RN   SDSG YT+ A+N  G C  T+
Sbjct: 969  EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 1028

Query: 351  GYLA---VESPTESYV 363
              +    VE P+   V
Sbjct: 1029 SLMVLPLVEEPSREVV 1044



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 110/491 (22%), Positives = 180/491 (36%), Gaps = 38/491 (7%)

Query: 3182 KIEWYHNGQPMRHSTRIKT-VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
            ++ WY +G+ ++ +   +   S  G   L I      D GE+VC    + G   T     
Sbjct: 557  EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFM 616

Query: 3241 CYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP----PKFITQIQDVTKLVE 3296
                  ++ E +   S  K  + ++ +    +     + EP    P  +T +QD T +  
Sbjct: 617  GQAFKSIH-EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTT-VSS 674

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDI---------LY- 3346
               A F  +     +P     W  +GK +  G +Y+   D G   L+I         LY 
Sbjct: 675  DSVAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYT 732

Query: 3347 CYEENSG---EYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK-LQTLED 3402
            C  +NS       C  T K  +D T+A    T K + I   +     E   +K L++ E 
Sbjct: 733  CTVKNSAGSVSSSCKLTIKAIKD-TEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 791

Query: 3403 SMVRRKDT---SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWN 3459
             M   K     +++EE  K  +      +     E    H E  +T T   + +V  +  
Sbjct: 792  KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEE--ITKTSQASEEVRTH-- 847

Query: 3460 GKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNII 3519
               +KA S   +  +   ++L+ +     D+   L        E        V G    +
Sbjct: 848  -AEIKAFSTQMSINEGQRLVLKANIAGATDAKWVLNGVELTNSEEYRYG---VSGSDQTL 903

Query: 3520 LESQLPKGMEGTIDKIAAL-EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFE 3578
               Q     EG +  I+   EG       LT   E  + P F + P    ++E  +  F 
Sbjct: 904  TIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFT 963

Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
            C +    + S  +EWF N  P+   S V          LEI      D+G YT KA N  
Sbjct: 964  CEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFR 1021

Query: 3639 GEATVSCKLQV 3649
            G+ + +  L V
Sbjct: 1022 GQCSATASLMV 1032



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 66/299 (22%), Positives = 116/299 (38%), Gaps = 22/299 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P  TL  ++  V  GQ  R    V      +V W  NG ++Q   +       G  TL I
Sbjct: 183  PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 242

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL-KDK 4632
            L+ +  DSG Y  V  N  GEA   A   V+          Q +    P  +   L + +
Sbjct: 243  LDCHTDDSGTYRAVCTNYKGEASDYATLDVT-GGDYTTYASQRRDEEVPRSVFPELTRTE 301

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
              A     + S       +  V+    +     S Y + S +A+  +  + E   E++  
Sbjct: 302  AYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSY-EHSASAEMKSAALEEKSLEEKST 360

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
             + +      + T+AA++ +T+P            R + VYEG+ A+F      +  PT+
Sbjct: 361  TRKI------KTTLAARI-LTKP------------RSMTVYEGESARFSCDTDGEPVPTV 401

Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             WLR+G ++  +   Q+      +   I +    D G ++     + G+ E    L ++
Sbjct: 402  TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 460



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 51/229 (22%), Positives = 96/229 (41%), Gaps = 9/229 (3%)

Query: 2795 CNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVSLDITHTYEEDSGIYTCKATN 2852
            C VE S     ++ W+ + K L     ++  +  D +Y  L I +  E D G + C+ + 
Sbjct: 546  CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTY-ELKINNLTESDQGEHVCEISG 604

Query: 2853 SKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPE 2912
              G++ T+        K+I+            ++ ++  E+ + +   P  P+    KP 
Sbjct: 605  EGGTSKTNLQFMGQAFKSIHEKVSKISETK--KSDQKTTESTVTRKTEPKAPEPISSKP- 661

Query: 2913 WIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLD 2972
             +I    +   V    +  +  V+   +P     W  +GK + QG ++KL+ D G   L+
Sbjct: 662  -VIVTGLQDTTVSSDSV-AKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 719

Query: 2973 LVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS-KDNLIERTQHPKGTE 3020
            +      DSG+YTC   N  G   +S  +   + KD   ++    K +E
Sbjct: 720  IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSE 768



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 85/378 (22%), Positives = 137/378 (36%), Gaps = 41/378 (10%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            ++ V EG    F C  +  G+P   + W   G+  +T +R            +I  + A 
Sbjct: 378  SMTVYEGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQAS 435

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIV--------LESQLPQGMSGEKIKELERGR 3815
            D G Y+    N  G       +T    R           ++S  P+  S E +K  +R +
Sbjct: 436  DEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVK 495

Query: 3816 ISD-------APKE------EPI----VSTPPKFITQIKSHTVEESEGVRFECRVEPKED 3858
              +       +P E      E +    VS PPK    +K+   +E    +  C VE    
Sbjct: 496  SPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEI--AKLTCVVESSVL 553

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKA 3917
                + WY++GK L     ++  Y   G   L I  +   D GE++C    + G   T  
Sbjct: 554  RAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNL 613

Query: 3918 TISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVT 3977
                +    I  +       K+S+  T  E+T+ + T E    E     +  K  P  VT
Sbjct: 614  QFMGQAFKSIHEKVSKISETKKSDQKTT-ESTVTRKT-EPKAPEP----ISSK--PVIVT 665

Query: 3978 QIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGW 4037
             +Q  T++      KF  +    G+P     W  +GK +    ++    D G   +    
Sbjct: 666  GLQD-TTVSSDSVAKFAVKAT--GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 722

Query: 4038 VYPEDSGEYLCRATNLYG 4055
                DSG Y C   N  G
Sbjct: 723  TDTSDSGLYTCTVKNSAG 740



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 82/365 (22%), Positives = 133/365 (36%), Gaps = 36/365 (9%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG+ A F C  +   +P  T+ W   GQ +    R++ T        +I    A D G Y
Sbjct: 383  EGESARFSCDTD--GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 440

Query: 2183 MCKATNKLG--EAVNTCTLKVA--GHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPK 2238
                 N  G  EA  T T++ A    + +    +  +   +++  EA     R++  EP 
Sbjct: 441  SVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPS 500

Query: 2239 ISPPRFVTELRGT----------------THVFEGKT----AHFECQVEPVHDPNLRIEF 2278
                   TE + T                T   + +     A   C VE        + +
Sbjct: 501  HPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTW 560

Query: 2279 YHNGKALQSAA--RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
            Y +GK L+     +FH + D G   L I +    D GE+  +     G   + +     A
Sbjct: 561  YKDGKKLKENGHFQFHYSAD-GTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQA 619

Query: 2337 KGSIISESQRPEGLEKI--RELESAEPFK-RPEIPEPVTRQRPVFTQPLQNIDNIQEGQT 2393
              SI  +  +    +K   +  ES    K  P+ PEP++  +PV    LQ+   +     
Sbjct: 620  FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPIS-SKPVIVTGLQD-TTVSSDSV 677

Query: 2394 AHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453
            A F  +    G+P     W ++ K I    +   + D G   + I      D G+Y C  
Sbjct: 678  AKFAVK--ATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTV 735

Query: 2454 SNLLG 2458
             N  G
Sbjct: 736  KNSAG 740



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FIS   +    EG N+ F C +  S +P+ +IEWF NN P+   +    +   +  SL+I
Sbjct: 945  FISQPRSQNINEGQNVLFTCEI--SGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 1002

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
             +    DSG YT KA N +G  + + SL
Sbjct: 1003 RNASVSDSGKYTIKAKNFRGQCSATASL 1030



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 42/169 (24%), Positives = 71/169 (42%), Gaps = 4/169 (2%)

Query: 1520 RAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPI 1579
            R+ + V ++    R    +  DI    ++     + Q   +R KY            AP 
Sbjct: 126  RSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSER-KYEVLSQQPFTLDHAPR 184

Query: 1580 CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDI 1639
             T  +++  +  GQ   F   +   S  T +V+WYHN   L+  S+   TN  G + L+I
Sbjct: 185  ITLRMRSHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 242

Query: 1640 MSCLPEDSGTYTCRAINALGEAVT-SGIAIVHSKKSIYLESQHEGALPR 1687
            + C  +DSGTY     N  GEA   + + +     + Y   + +  +PR
Sbjct: 243  LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPR 291



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 3/113 (2%)

Query: 2622 KEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKN 2681
            KE  +    ++ +   +  AP F +  +S + + EGQ+V    ++    +P+ +IEWFKN
Sbjct: 923  KEGIVKCQYDLTLSKELSDAPAFISQPRSQN-INEGQNVLFTCEISG--EPSPEIEWFKN 979

Query: 2682 GVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + ++  + +  +    + +L I +    DSG YT KA N  G+  +TAS+ +
Sbjct: 980  NLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 1032



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 44/186 (23%), Positives = 76/186 (40%), Gaps = 8/186 (4%)

Query: 3054 FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGT 3113
            F   + I+EGQ    +A++    D     +W  NG  +  S   R   +     L I   
Sbjct: 853  FSTQMSINEGQRLVLKANIAGATDA----KWVLNGVELTNSEEYRYGVSGSDQTLTIKQA 908

Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173
               D G  +C +  K G  +    L  + K     P F +  ++ + + +GQ+  F C +
Sbjct: 909  SHRDEGILTCISKTKEGIVKCQYDLT-LSKELSDAPAFISQPRS-QNINEGQNVLFTCEI 966

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                +P  +IEW+ N  P+  S+ +          L+I      DSG+Y  +A N  G+ 
Sbjct: 967  S--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQC 1024

Query: 3234 FTRATI 3239
               A++
Sbjct: 1025 SATASL 1030



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G    F   V+  + P   + W+HNG +++   +   T+  G + L+IL  + +DSGTY 
Sbjct: 197  GQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 254

Query: 2184 CKATNKLGEAVNTCTLKVAG 2203
               TN  GEA +  TL V G
Sbjct: 255  AVCTNYKGEASDYATLDVTG 274



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            +  AP  T  ++S+ ++  GQ+      V+ +  P  +++W+ NGV L   +++  T   
Sbjct: 179  LDHAPRITLRMRSH-RVPCGQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTS 235

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G++TL I     DDSG Y    TN  GEA   A++ +
Sbjct: 236  GVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 272



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 23/70 (32%), Positives = 40/70 (57%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            ++ P  +++WY NG  L++ S+   T+  G +TL+++D +  DSG Y     N +GEA  
Sbjct: 207  QSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASD 266

Query: 2998 SSTVYCTSKD 3007
             +T+  T  D
Sbjct: 267  YATLDVTGGD 276



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 30/108 (27%), Positives = 54/108 (50%), Gaps = 3/108 (2%)

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT 1087
            +Y   +++   +   PR    ++ ++++  GQ+  F   V  QS  T  V+WY NG ++ 
Sbjct: 168  KYEVLSQQPFTLDHAPRITLRMR-SHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQ 224

Query: 1088 SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             +++I   +  G + L+I     +DSG Y  V  N  GEA   A++ V
Sbjct: 225  ESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 272



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 5/134 (3%)

Query: 354  AVESPTESYVQDQRSQY--ITDTQQRE--TEERIEISEKALAPQFVKVCQDRDVTEGKMT 409
            ++ S  ES+V+   S +  I++  Q E  T + ++   + + P+   +  D  + EGK+ 
Sbjct: 1096 SMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVL 1155

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHALMITNVTLSDSGVVTCVAR 468
               C  TG P PEVTW    R+I      +  + N      L+I +V   D G+ T    
Sbjct: 1156 TVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLG 1215

Query: 469  NKSGETAFQCRLNV 482
            N+ G  +    +++
Sbjct: 1216 NEFGSDSATVNIHI 1229



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 4/135 (2%)

Query: 1803 QSKASLQLESQHESALQKIQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLSEGQS 1861
            +  A   + S++ES    ++  + S R Y+        ++ APR   ++    ++  GQ+
Sbjct: 141  ERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH-RVPCGQN 199

Query: 1862 AHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
              +   ++    P   V+WY NG  LQ   +   +N  G   L+IL  + +DSG Y    
Sbjct: 200  TRFILNVQS--KPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVC 257

Query: 1922 INNLGQAVSSIRLNV 1936
             N  G+A     L+V
Sbjct: 258  TNYKGEASDYATLDV 272



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 2/107 (1%)

Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
            KY+  S Q   +  AP  T+ M+  RV   Q   F   +     P   V+W  NGV ++ 
Sbjct: 168  KYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNV--QSKPTAEVKWYHNGVELQE 225

Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            S+++   +  G + L +   + +DSGTY     N  GEA   +TL V
Sbjct: 226  SSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 272



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 36/147 (24%), Positives = 68/147 (46%), Gaps = 9/147 (6%)

Query: 3391 EGGLEKLQTLEDSMVR-RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
            EG L  +   ++ +V+ + D ++ +E   AP F +     +N+ EG+N  F   ++   +
Sbjct: 913  EGILTCISKTKEGIVKCQYDLTLSKELSDAPAF-ISQPRSQNINEGQNVLFTCEIS--GE 969

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P+ ++EW+ N   +   S            LEI      DSG+Y  +A N  G+   TAS
Sbjct: 970  PSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATAS 1029

Query: 3510 MKV-----QGKRNIILESQLPKGMEGT 3531
            + V     +  R ++L +     ++G+
Sbjct: 1030 LMVLPLVEEPSREVVLRTSGDTSLQGS 1056



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 2/94 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P FI   +S    EG  + F   I   G+P+ +IEW KN   I  SS  +        SL
Sbjct: 943  PAFISQPRSQNINEGQNVLFTCEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSL 1000

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTP 730
            ++ + ++ DSG+YT +A +  G     A L V P
Sbjct: 1001 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLP 1034



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 35/144 (24%), Positives = 64/144 (44%), Gaps = 5/144 (3%)

Query: 1946 SQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIKNAEVTEGHPVHLEATLTPV 2004
            S++ES    ++  +   R    +    F ++  P+    +++  V  G        L   
Sbjct: 150  SRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRF--ILNVQ 207

Query: 2005 NDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            + PT  V+WY NG  +Q+  +   T   G + L+IL  + +D+GTY    TN  GEA  +
Sbjct: 208  SKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA--S 265

Query: 2065 SSVKVDAKSGLYLDTLDEQRLKKI 2088
                +D   G Y     ++R +++
Sbjct: 266  DYATLDVTGGDYTTYASQRRDEEV 289



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 5/114 (4%)

Query: 3674 KLEETLHKREEITIEDE--KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731
            K ++T  ++ E+  +      + PR T+ ++ +  VP G    F   V+    PT  + W
Sbjct: 160  KTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH-RVPCGQNTRFILNVQ--SKPTAEVKW 216

Query: 3732 FHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +HNG      S++H  N  G + L+I   +  D+G Y    TN  G A+  A +
Sbjct: 217  YHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATL 270



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 3/105 (2%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            PR    +R +  V  G+   F   V+    P   +++YHNG  LQ +++ H T   G ++
Sbjct: 183  PRITLRMR-SHRVPCGQNTRFILNVQS--KPTAEVKWYHNGVELQESSKIHYTNTSGVLT 239

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQR 2346
            L+I  C  +D+G Y     N  G  +   ++ VT        SQR
Sbjct: 240  LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQR 284



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G N  F  NV+    PT +++W+ N   L   ++   T+    ++L+I   + +DSG Y 
Sbjct: 197  GQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 254

Query: 2848 CKATNSKGSATTSGSLRCTG 2867
               TN KG A+   +L  TG
Sbjct: 255  AVCTNYKGEASDYATLDVTG 274



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/74 (32%), Positives = 38/74 (51%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P  +V+W++NG +L    +    +  G++ L+IL C+ ++SG Y  V TN  G  S  A 
Sbjct: 210  PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYAT 269

Query: 3372 LKCTSKENLILDSQ 3385
            L  T  +     SQ
Sbjct: 270  LDVTGGDYTTYASQ 283



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 69/289 (23%), Positives = 119/289 (41%), Gaps = 28/289 (9%)

Query: 4223 QYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQ 4282
            Q+QR   E E     R V   Q + +++ EL   + KE     ++S K+ + +    ++ 
Sbjct: 1    QWQRIMAEREDEELLRPVTTTQHLSEYKSELD-FMSKE-----EKSRKKSRRQREVTEIT 54

Query: 4283 ELENEQVIKESRLRESTHQYA--IPGDKVTSNTVAKSMAQRYE------DNLDQTEEVTE 4334
            E+E E  I +   RES+   +  +   +  S T  + M    E         ++ E+ TE
Sbjct: 55   EIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTE 114

Query: 4335 QRVQKKVTQKPRIPDPSESTVHGKEVHVAK-QKQTQKEVVGDKEITRKITSTETTEIEHK 4393
            +R       +PR P P  S     E  +++ ++  + ++    E  +    T+ T  E K
Sbjct: 115  RRSPTPERTRPRSPSPVSS-----ERSLSRFERSARFDIFSRYESMKAALKTQKTS-ERK 168

Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
                E + + P      P  T +M+  RV   +  RF +    +P   +KWY     ++ 
Sbjct: 169  ---YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQE 225

Query: 4454 SPDFQIHTFSTKSILI--IRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
            S   +IH  +T  +L   I     +DS  + AV  N  G A   A L V
Sbjct: 226  SS--KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 272



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 25/93 (26%), Positives = 52/93 (55%), Gaps = 3/93 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F+++ R + ++ EG+   F C++    +P+  IE++ N   +  ++   I+      S
Sbjct: 943  PAFISQPR-SQNINEGQNVLFTCEISG--EPSPEIEWFKNNLPISISSNVSISRSRNVYS 999

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
            L+I++    D+G+Y++KA N  G C++  S+ V
Sbjct: 1000 LEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 1032



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 8/144 (5%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           +++ T  +I+ +   LA + +   +   V EG+  RF C   G P P VTW    + +  
Sbjct: 356 EEKSTTRKIKTT---LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLST 412

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
              H++   +       I++V  SD G  + V  N  G+   +  L  I+K +V      
Sbjct: 413 SARHQVTTTKY-KSTFEISSVQASDEGNYSVVVENSEGKQEAEFTL-TIQKARVTEKAVT 470

Query: 495 ERFSTLNVREGEPVVLNARAVGTP 518
              S   V+  EP V +  AV +P
Sbjct: 471 ---SPPRVKSPEPRVKSPEAVKSP 491



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 4/100 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            +S  P FI+Q +S  + E + V F C +  +  P+  IEW++N   +             
Sbjct: 939  LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPE--IEWFKNNLPISISSNVSISRSRN 996

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              SL+I      DSG+Y  +A N  G+    AT S   LP
Sbjct: 997  VYSLEIRNASVSDSGKYTIKAKNFRGQ--CSATASLMVLP 1034



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+   +++SH V   +  RF   V+ K  P   ++WY NG  L    +       G ++L
Sbjct: 183  PRITLRMRSHRVPCGQNTRFILNVQSK--PTAEVKWYHNGVELQESSKIHYTNTSGVLTL 240

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            +IL  + +DSG Y     N  GE    AT+
Sbjct: 241  EILDCHTDDSGTYRAVCTNYKGEASDYATL 270



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
            NI EGQ   F C +   G+P+ ++EWF+N   I  SS ++ +      S+ I +    D 
Sbjct: 953  NINEGQNVLFTCEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDS 1010

Query: 2447 GVYMCRASNLLGE 2459
            G Y  +A N  G+
Sbjct: 1011 GKYTIKAKNFRGQ 1023



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            PR T  +++   +  GQ+  F   V     P  +++WYHNG  ++ S++I   +  G + 
Sbjct: 183  PRITLRMRS-HRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 239

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
            L+I      DSG Y     N  GE    AT++  G
Sbjct: 240  LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 274



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 23/92 (25%), Positives = 37/92 (40%), Gaps = 1/92 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD-GMYHFDI 4169
            P F+S P +  + EG+   F C ++G P P + W  N   I   S   ++    +Y  +I
Sbjct: 943  PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 1002

Query: 4170 PKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIP 4201
                  D+GK  +              L V+P
Sbjct: 1003 RNASVSDSGKYTIKAKNFRGQCSATASLMVLP 1034



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 785 GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
           G+N  F   L   S PT  V+WY +G  +  SS+I      G ++L I+    +D+G+Y 
Sbjct: 197 GQNTRFI--LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 254

Query: 845 VRAVNKLGEAISTASIRVAARSTVT 869
               N  GEA   A++ V      T
Sbjct: 255 AVCTNYKGEASDYATLDVTGGDYTT 279



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 23/61 (37%), Positives = 31/61 (50%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V+W+HNG  L   S++   N  G + LEI   +  D+G Y    TN  GEA+    L V 
Sbjct: 214  VKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 273

Query: 3651 G 3651
            G
Sbjct: 274  G 274



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 20/51 (39%), Positives = 30/51 (58%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            ++W++NG  ++ S +I      G++ LEIL   T DSGTY    TN  G+A
Sbjct: 214  VKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA 264



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 2/80 (2%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            G+N  F   L     P  +V+WY NG  L+  S+       G + LEI   + +DSG Y 
Sbjct: 197  GQNTRFI--LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYR 254

Query: 3495 CRAYNNYGEAVTTASMKVQG 3514
                N  GEA   A++ V G
Sbjct: 255  AVCTNYKGEASDYATLDVTG 274



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/80 (27%), Positives = 36/80 (45%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+I  + R+ ++  G + +F + +   P   V W+ NG  L  S+K     T    TL +
Sbjct: 183 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 242

Query: 326 RNTQKSDSGHYTLLAENPNG 345
            +    DSG Y  +  N  G
Sbjct: 243 LDCHTDDSGTYRAVCTNYKG 262



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 20/64 (31%), Positives = 32/64 (50%)

Query: 666 PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAV 725
           PT +++W  NG  ++ SS+       G ++L++L  +  DSG Y     +  G A   A 
Sbjct: 210 PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYAT 269

Query: 726 LHVT 729
           L VT
Sbjct: 270 LDVT 273



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 19/53 (35%), Positives = 28/53 (52%)

Query: 2538 PSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            P+   +WY NGVEL+  S+   T+  G +TL+I     +D+G Y     N  G
Sbjct: 210  PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKG 262



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHA 449
           AP+     +   V  G+ TRF   V  +P  EV W+ N  ++++  + KI   N SG   
Sbjct: 182 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQE--SSKIHYTNTSGVLT 239

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           L I +    DSG    V  N  GE +    L+V
Sbjct: 240 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 272



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYT 4679
            PP+I     D  + EG+ +  +C   G+P P V W  G + I   +   F +  T D  T
Sbjct: 1137 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 1196

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            L I +   +D G Y     N  G  +    + +
Sbjct: 1197 LIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 1229



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 20/69 (28%), Positives = 31/69 (44%)

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
            L     PT  V+W+HNG  +   S+       G + L+I+   + D+G Y     N+ G 
Sbjct: 204  LNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 263

Query: 1261 AHTSAIVRV 1269
            A   A + V
Sbjct: 264  ASDYATLDV 272



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/101 (23%), Positives = 42/101 (41%), Gaps = 2/101 (1%)

Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
            ++  T+  AP+ +  + +     G N      +Q     T  V+W+ NG  ++   +   
Sbjct: 174  QQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHY 231

Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                  + L++L  + +DSG Y    TN  GEA     L V
Sbjct: 232  TNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 272



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 17/54 (31%), Positives = 30/54 (55%)

Query: 2406 PTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            PT +V+W+ N   +++SS+I  T+  G +++ I     +D G Y    +N  GE
Sbjct: 210  PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 263



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 81/413 (19%), Positives = 158/413 (38%), Gaps = 55/413 (13%)

Query: 1017 LEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMT 1076
            LEK    E+ ++ S+ +EE     +   F   +     I EGQ    +A +   +D    
Sbjct: 825  LEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMS----INEGQRLVLKANIAGATD---- 876

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             +W  NG ++T++   +         L I      D G+ T +++   G  +    +T+ 
Sbjct: 877  AKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS 936

Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFV-----EPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
               S   + I +   +     +   F      EP  +IE    + P+ +   S+   +S 
Sbjct: 937  KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISI---SSNVSISR 993

Query: 1192 GKNIH-LECRLEPMGDP---TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADT 1247
             +N++ LE R   + D    T++ + F    S T         +    + +++  TS DT
Sbjct: 994  SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEP--SREVVLRTSGDT 1051

Query: 1248 ---GEYTVRAV-----------NHLGSAHTSAIVRV------------IERSDIVTDTQN 1281
               G ++ ++V           +   S+  S++  +            ++ S +   + +
Sbjct: 1052 SLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSS 1111

Query: 1282 EQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQT 1341
               I  +  LE +   +K ++  I  +  P+      +I   EG  + + C     G+ T
Sbjct: 1112 FMGISNMTQLESST--SKMLKAGIRGIP-PKIEALPSDISIDEGKVLTVACAF--TGEPT 1166

Query: 1342 MRVEWFCNGKPIKTGH--RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
              V W C G+ I +    RF      D   L ++ V  +D G+YT    N+ G
Sbjct: 1167 PEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 1219



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/147 (19%), Positives = 60/147 (40%), Gaps = 8/147 (5%)

Query: 1794 AVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGP 1853
            ++++ ++    ++ +++ S     +  + QLE S+       ++  +   P  I  L   
Sbjct: 1091 SMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM----LKAGIRGIPPKIEALPSD 1146

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH--RYRTSNDFGFAALDILTVYG 1911
              + EG+     C     P P   V W   G+ + S    R+   N      L I+ V  
Sbjct: 1147 ISIDEGKVLTVACAFTGEPTPE--VTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQK 1204

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            +D G YT    N  G   +++ ++++S
Sbjct: 1205 QDGGLYTLSLGNEFGSDSATVNIHIRS 1231



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 15/42 (35%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP   +LP  ++++EG+     C  TG P P V W   G  I
Sbjct: 1137 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 1178



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG--GAS 546
            + PK     S +++ EG+ + +     G PTP +TW   G  I    + R H +     +
Sbjct: 1136 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 1195

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            TL I   +  D   Y  +  N  GS +    ++
Sbjct: 1196 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIH 1228



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
            +PP       ++++  G+++ +    TG    +V W   G+K+  Q   R  I   D   
Sbjct: 1136 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 1195

Query: 4570 TLLILEAYPQDSGKYECVAINSAG 4593
            TL+I++   QD G Y     N  G
Sbjct: 1196 TLIIMDVQKQDGGLYTLSLGNEFG 1219



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
            EGQ+  +   +   G+PS   EW+ N + + + S    +      +L+I +   +D+G Y
Sbjct: 956  EGQNVLFTCEIS--GEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 1013

Query: 2582 MCKAINRAG 2590
              KA N  G
Sbjct: 1014 TIKAKNFRG 1022



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/66 (27%), Positives = 33/66 (50%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E   +P  +IEW+ N   +   S   ++      +L++ +    DSG YT KA N RG+ 
Sbjct: 965  EISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQC 1024

Query: 2996 FTSSTV 3001
              ++++
Sbjct: 1025 SATASL 1030



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 1/98 (1%)

Query: 4714 QPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHE 4772
            QP   D+ P +T  +R   V  GQ  +F   + SK    ++W   G  + E+      + 
Sbjct: 175  QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 234

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                 L I + + +D+GT+    T   G+    A L V
Sbjct: 235  SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 272



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 50   TQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
            TQ+ESS  +  + AG  G   PP  E +  +    +G          G PTP V+W+   
Sbjct: 1119 TQLESSTSKM-LKAGIRG--IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWS-CG 1174

Query: 110  APLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
               +   +    + E T D+ +L+I  +   D G YT +  N++G    +V I
Sbjct: 1175 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 1227



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLNDFG 3751
            PP+    +  +I + EG  +   C     G+PT  + W   GR   +    R H  N   
Sbjct: 1137 PPKIEA-LPSDISIDEGKVLTVACAF--TGEPTPEVTWSCGGRKIHSQEQGRFHIENTDD 1193

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               L I  +  +D G YT    N++GS + T  I
Sbjct: 1194 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 1227



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PR   R +S   V  GQ+  F   ++  +    +V+W+ NG  +    +    +  G + 
Sbjct: 183  PRITLRMRS-HRVPCGQNTRFILNVQ--SKPTAEVKWYHNGVELQESSKIHYTNTSGVLT 239

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVG 1526
            L+I+D   +DSG Y     N  G
Sbjct: 240  LEILDCHTDDSGTYRAVCTNYKG 262



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/74 (27%), Positives = 30/74 (40%)

Query: 4003 PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAV 4062
            P  +V+W+ NG  L   ++       G + +     + +DSG Y    TN  G     A 
Sbjct: 210  PTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYAT 269

Query: 4063 IKTTGKPGIVYDSQ 4076
            +  TG     Y SQ
Sbjct: 270  LDVTGGDYTTYASQ 283



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 4/62 (6%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EGQ + L+A +   TD     +W  NGV LT     +        TL+I    + D GI 
Sbjct: 861  EGQRLVLKANIAGATDA----KWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGIL 916

Query: 2716 TC 2717
            TC
Sbjct: 917  TC 918


>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
          Length = 1100

 Score =  114 bits (274), Expect = 9e-24
 Identities = 106/383 (27%), Positives = 163/383 (42%), Gaps = 47/383 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P I W + N  I +    +     ++++L I  V ++D+ ++   AEN  G     
Sbjct: 326  GNPVPTITWMKVNGYIPSKARLR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFR 381

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKV 4554
              L V             P +     +  + SG  +R + K TG KP   Y WLKNG  +
Sbjct: 382  GQLQV----------YTYPHWVEKLNDTQLDSGSPLRWECKATG-KPRPTYRWLKNGVPL 430

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R +++       L+I      D+G Y+C+A N  G     AE  +           
Sbjct: 431  SPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI----------- 475

Query: 4615 QTKAANAPPEIIEPLKDK-IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                A+AP   +  LK   IV + Q +   CK  G P PT+ W KGD+ ++ +K   +  
Sbjct: 476  ---LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAI-- 530

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR-DIVV 4732
               + +LRI  A   DEG Y C   N  G   + A L V +P + +    LTP R ++ V
Sbjct: 531  -LPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE----LTPKRTELTV 585

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALI---PETPDFQMIH-EGNNAVLLIGNTYEEDT 4788
             E      K    + +  T  W  +G  I    E   F+ I  + ++A L+I N      
Sbjct: 586  GESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHA 645

Query: 4789 GTFTCRATTAAGQVETSAKLVVK 4811
            G + CR  T A  V   A+L+V+
Sbjct: 646  GRYGCRVQTTADSVSDEAELLVR 668



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 100/391 (25%), Positives = 159/391 (40%), Gaps = 34/391 (8%)

Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            + ++     E  G P+P  +W R    I    D++ ++    + +I      +DS  +  
Sbjct: 115  DEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYR-YSLIDGTFIISNPSEAKDSGHYQC 173

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543
            +A N  G+   S    ++        G        T   V+V  GQ V L        P 
Sbjct: 174  LATNTVGSI-LSREATLQFAYLGNFSG-------RTRSAVSVREGQGVVLMCSPPPHSPE 225

Query: 4544 DVY-WLKNG--KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             +Y W+ N     V  D R  I +E G   L I +    D G Y C+  N+   AR    
Sbjct: 226  IIYSWVFNEFPSFVAEDSRRFISQETGN--LYISKVQTSDVGSYICLVKNTVTNAR---- 279

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             V+S P               P   +        A+G  ++  C  +G P+PT+ W K +
Sbjct: 280  -VLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVN 338

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQAD 4719
              I PSK         +  L I     +D G Y+C A NS G+ +   +L+V T P   +
Sbjct: 339  GYI-PSK---ARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 394

Query: 4720 NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                   L D  +  G P +++ + T K +PT +WL+ G  +P +P  ++  E  N VL+
Sbjct: 395  K------LNDTQLDSGSPLRWECKATGKPRPTYRWLKNG--VPLSPQSRV--EMVNGVLM 444

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            I N  + D G + C A    G +  SA+L +
Sbjct: 445  IHNVNQSDAGMYQCLAENKYGAIYASAELKI 475



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 90/378 (23%), Positives = 137/378 (36%), Gaps = 30/378 (7%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P  +  W    FP   + D +         L I +V   D   +  + +N    A+  + 
Sbjct: 224  PEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSP 283

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ-NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
                  R  G  G   P   +     V    G  V+++    G     + W+K    V  
Sbjct: 284  PTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK----VNG 339

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
             I +K         L I      D+G YEC A NS G               K+  + Q 
Sbjct: 340  YIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRG---------------KNSFRGQL 384

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
            +    P   +E L D  +  G  + + CK  GKP PT +W K    + P    +M     
Sbjct: 385  QVYTYP-HWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG-- 441

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L I      D G Y+C+A N  G +  +A+LK+        L  L   + I+V + Q
Sbjct: 442  --VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLK--KTIIVTKDQ 497

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
                + +     KPTI W +    + E     ++ +G+  +L   N  + D G + CR  
Sbjct: 498  EVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRIL---NASKSDEGKYVCRGE 554

Query: 4797 TAAGQVETSAKLVVKSKT 4814
               G  E  A L VK  T
Sbjct: 555  NVFGSAEIIASLSVKEPT 572



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 58/204 (28%), Positives = 89/204 (43%), Gaps = 10/204 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P +V+   D  +  G   R++C+ TG+P P   W  N   +      +++     N  LM
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV-----NGVLM 444

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I NV  SD+G+  C+A NK G       L ++      A   +++  T+ V + + VV+ 
Sbjct: 445 IHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK--TIIVTKDQEVVIE 502

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G+P P I+W+K    +  N  + I  DG   +L I  A  SD   Y C  +NV GS
Sbjct: 503 CKPQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEGKYVCRGENVFGS 559

Query: 572 TATRARLYXXXXXXXXXXQKRLHL 595
               A L            KR  L
Sbjct: 560 AEIIASLSVKEPTRIELTPKRTEL 583



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 53/174 (30%), Positives = 80/174 (45%), Gaps = 14/174 (8%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G   + +C   G P P +TW     ++      K  + +S    L I NV L D+G+  
Sbjct: 314 KGTTVKMECFALGNPVPTITWM----KVNGYIPSKARLRKS-QAVLEIPNVQLDDAGIYE 368

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C A N  G+ +F+ +L V        P +VE+ +   +  G P+    +A G P P   W
Sbjct: 369 CRAENSRGKNSFRGQLQVY-----TYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRW 423

Query: 525 QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            K+GVP+  +P+ R+    G   L I     SDA  YQC A+N  G+    A L
Sbjct: 424 LKNGVPL--SPQSRVEMVNG--VLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 473



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 80/313 (25%), Positives = 127/313 (40%), Gaps = 40/313 (12%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P + +K+   ++      R+E +  G+P P  +W +   P+  SP  ++       +L+I
Sbjct: 390  PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVE--MVNGVLMI 445

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT--AQNVNVTSG 4528
              V   D+ ++  +AEN+ G    SA L +             P+F L    + + VT  
Sbjct: 446  HNVNQSDAGMYQCLAENKYGAIYASAELKILAS---------APTFALNQLKKTIIVTKD 496

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            Q V ++ K  G+    + W K  + V+ + R  IL  DG  +L IL A   D GKY C  
Sbjct: 497  QEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL-PDG--SLRILNASKSDEGKYVCRG 553

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N  G     AE + SL       K  T+    P       K   +  G++I  +CK + 
Sbjct: 554  ENVFG----SAEIIASLSV-----KEPTRIELTP-------KRTELTVGESIVLNCKAIH 597

Query: 4649 KPLPTVQWY---KGDKL--IKPSKYFQMSRT-ADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                 V +Y   KG  +   +   +F+  R  A    L I        G Y C    +A 
Sbjct: 598  DASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTAD 657

Query: 4703 RVTVAAKLKVTQP 4715
             V+  A+L V  P
Sbjct: 658  SVSDEAELLVRGP 670



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 4/113 (3%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P   +K  +++L  G+  +++ + +G PRP   W KNG  L   ++ E++    +  L +
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV----NGVLMI 445

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378
            N  +SD+G Y  LAEN  G I  S  L + +   ++  +Q  + I  T+ +E
Sbjct: 446 HNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQE 498



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 50/192 (26%), Positives = 76/192 (39%), Gaps = 18/192 (9%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+    F   V  ++G     E   +  G+    I W      I +  R+R   A    V
Sbjct: 300  PKIEVHFPFTVTAAKGTTVKMECFAL--GNPVPTITWMKVNGYIPSKARLRKSQA----V 353

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   +  D+G Y CRA N  G+     +L+         P +   + + + L  G   
Sbjct: 354  LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY-----PHWVEKLNDTQ-LDSGSPL 407

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             +EC       P  +  W  NG P+   +R++ V+     VL I      D+G Y C A 
Sbjct: 408  RWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAE 461

Query: 3228 NKYGEDFTRATI 3239
            NKYG  +  A +
Sbjct: 462  NKYGAIYASAEL 473



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 43/158 (27%), Positives = 60/158 (37%), Gaps = 14/158 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG       W  NG  +    R+  V      VL I     +D+G Y C A NK+G    
Sbjct: 414  TGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYA 469

Query: 3135 SVKLECVDKSKGQKPRFT-THIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            S +L    K     P F    ++    +   Q    EC   P   P   I W    + +R
Sbjct: 470  SAEL----KILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVR 523

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             + RI  + D    +L+       D G+YVCR  N +G
Sbjct: 524  ENKRIAILPDGSLRILN---ASKSDEGKYVCRGENVFG 558



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 49/170 (28%), Positives = 74/170 (43%), Gaps = 21/170 (12%)

Query: 421 PEV--TWFINDRQ--IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK------ 470
           PE+  +W  N+    + +D + + +  E+GN  L I+ V  SD G   C+ +N       
Sbjct: 224 PEIIYSWVFNEFPSFVAED-SRRFISQETGN--LYISKVQTSDVGSYICLVKNTVTNARV 280

Query: 471 -SGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            S  T    R + +  E    PK    F  T+   +G  V +   A+G P P ITW K  
Sbjct: 281 LSPPTPLTLRNDGVMGEY--EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVN 338

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I     LR       + L+IP  +  DA  Y+C A+N  G  + R +L
Sbjct: 339 GYIPSKARLR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQL 384



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 6/92 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P +    +D  L   S   +EC+       + R  W  NG PL   SRV+ +N     +L
Sbjct: 390  PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VL 443

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I  V Q DAG+Y C A N++G    S +L++
Sbjct: 444  MIHNVNQSDAGMYQCLAENKYGAIYASAELKI 475



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDID 3758
            VE  ++  +  G P+ ++C+      PT R  W  NG P +  SRV  +N      L I 
Sbjct: 393  VEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VLMIH 446

Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
             +   DAG Y C A NK+G+   +A++   A       +QL + +   K +E+
Sbjct: 447  NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEV 499



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
           G+P+P ++W K G R +  NK   I      +LR+ N  KSD G Y    EN  G     
Sbjct: 507 GSPKPTISW-KKGDRAVRENKRIAILPDG--SLRILNASKSDEGKYVCRGENVFGSAEII 563

Query: 351 GYLAVESPTESYVQDQRSQ 369
             L+V+ PT   +  +R++
Sbjct: 564 ASLSVKEPTRIELTPKRTE 582



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 1701 SAQDEVITQAPVFTMPM--KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            SA+ +++  AP F +    K I V ++Q    E +  P G PK  + W +    +  + R
Sbjct: 470  SAELKILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKR 527

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
            +  + D     LN    +  D G Y CR  N  G A   ++L V+    ++L
Sbjct: 528  IAILPDGSLRILN---ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIEL 576



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 3819 APKEEPIVSTPPKF-ITQIKSHT-VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            A  E  I+++ P F + Q+K    V + + V  EC+  P+  PK  I W +  + +    
Sbjct: 469  ASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENK 526

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
            R   + D    SL IL     D G+Y+CR  N FG     A++S K+
Sbjct: 527  RIAILPDG---SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 570



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 7/101 (6%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P ++  L D  +L  G    +E + T    PT R  W K+G P++  SR+  +       
Sbjct: 390 PHWVEKLNDT-QLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV---- 442

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I ++   DAG Y   A NK G   ++A +++ A +   A
Sbjct: 443 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA 483



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 26/184 (14%)

Query: 404 TEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVT-LSDS 460
           ++ K    +C V G P P   W  N  +I    DY + ++     +   +I+N +   DS
Sbjct: 114 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLI-----DGTFIISNPSEAKDS 168

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-----STLNVREGEPVVLN-ARA 514
           G   C+A N  G        +++ +E  +   ++  F     S ++VREG+ VVL  +  
Sbjct: 169 GHYQCLATNTVG--------SILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 220

Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
             +P    +W  +  P     + R         L I + + SD   Y C  +N    T T
Sbjct: 221 PHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKN----TVT 276

Query: 575 RARL 578
            AR+
Sbjct: 277 NARV 280



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 6/96 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P +   + D ++       +E +    G P+    WL+NGVP+   +R+  ++      L
Sbjct: 390  PHWVEKLNDTQLDSGSPLRWECKA--TGKPRPTYRWLKNGVPLSPQSRVEMVNG----VL 443

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +  VN  D+G Y C A N+ G    S+ L + + A
Sbjct: 444  MIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA 479



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 41/145 (28%), Positives = 62/145 (42%), Gaps = 18/145 (12%)

Query: 1801 FVQSKASLQLESQHESALQKIQQLEDSSRYQRREDV---------EVAVNQAPRFITQLN 1851
            ++ SKA L+ +SQ    +  +Q L+D+  Y+ R +          ++ V   P ++ +LN
Sbjct: 340  YIPSKARLR-KSQAVLEIPNVQ-LDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLN 397

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
              T+L  G    +EC+    P P  R  W  NG  L    R    N      L I  V  
Sbjct: 398  D-TQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVN----GVLMIHNVNQ 450

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNV 1936
             D+G Y C A N  G   +S  L +
Sbjct: 451  SDAGMYQCLAENKYGAIYASAELKI 475



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 1171 EISKSKPVF-VQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            +I  S P F +  L     V++ + + +EC+  P G P   + W    R+V    R    
Sbjct: 474  KILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAIL 531

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
             D    +L I++A+ +D G+Y  R  N  GSA   A + V E + I
Sbjct: 532  PDG---SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRI 574



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 3/82 (3%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           +P G P   I W K  +++  + R  +I   G  SL +L+ +  D G+Y CR  +  G A
Sbjct: 504 KPQGSPKPTISWKKGDRAVRENKRI-AILPDG--SLRILNASKSDEGKYVCRGENVFGSA 560

Query: 721 ETKAVLHVTPRATIERTSQHPE 742
           E  A L V     IE T +  E
Sbjct: 561 EIIASLSVKEPTRIELTPKRTE 582



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +   +G  +  EC    +  PT  I W   N  +PS  R +     S   L+I +   +D
Sbjct: 310  VTAAKGTTVKMECFALGNPVPT--ITWMKVNGYIPSKARLRK----SQAVLEIPNVQLDD 363

Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864
            +GIY C+A NS+G  +  G L+
Sbjct: 364  AGIYECRAENSRGKNSFRGQLQ 385



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/115 (27%), Positives = 46/115 (40%), Gaps = 6/115 (5%)

Query: 3695 PRFTV-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P F + ++K  I V +   V  +C+  P G P   I W    R      R+  L D    
Sbjct: 480  PTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDGSLR 537

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
             L+       D G+Y CR  N +GSA   A ++      I L  +  +   GE I
Sbjct: 538  ILNAS---KSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESI 589



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/120 (26%), Positives = 47/120 (39%), Gaps = 11/120 (9%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            P G     I W    + +  + RI  +   G   L IL    +D G Y CR  N +G AE
Sbjct: 505  PQGSPKPTISWKKGDRAVRENKRI-AILPDGS--LRILNASKSDEGKYVCRGENVFGSAE 561

Query: 3134 ISVKLECVDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            I   L   + ++ +  P+ T        L  G+S    C  +     D+   W   GQP+
Sbjct: 562  IIASLSVKEPTRIELTPKRTE-------LTVGESIVLNCKAIHDASLDVTFYWTLKGQPI 614



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 5/95 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + + Q    +C+  P G P   + W + ++ + ++ RI    D    S+ I +    DEG
Sbjct: 493  VTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 547

Query: 2448 VYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPE 2482
             Y+CR  N+ G               I+L  +  E
Sbjct: 548  KYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTE 582



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 54/238 (22%), Positives = 86/238 (36%), Gaps = 23/238 (9%)

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
           V NAR +  PTP +T + DGV     P++ +H         +  AK +     +C A   
Sbjct: 275 VTNARVLSPPTP-LTLRNDGVMGEYEPKIEVHFP-----FTVTAAKGTTVKM-ECFALGN 327

Query: 569 AGSTATRARL--YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIP 626
              T T  ++  Y          Q  L +P                 Y    E +R    
Sbjct: 328 PVPTITWMKVNGYIPSKARLRKSQAVLEIPN--------VQLDDAGIYECRAENSRGKNS 379

Query: 627 PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686
              + +VY  P ++  L       G  + +E +    G P     WLKNG  +   SR  
Sbjct: 380 FRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKA--TGKPRPTYRWLKNGVPLSPQSRVE 437

Query: 687 SIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
            +   G + +   ++N  D+G Y C A +  G     A L +   A     +Q  +T+
Sbjct: 438 MV--NGVLMIH--NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTI 491



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            +R     R  + V   P +   L++ +   G+ +  EC+       T R  W  NG P+ 
Sbjct: 374  SRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLS 431

Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
               R     E     L + +V   D+G+Y C A N+ G    S  L+++A
Sbjct: 432  PQSRV----EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILA 477



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 6/91 (6%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P + +   + +   G   ++E K  G P P   W +   PL   ++  M        V L
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM-----VNGV-L 443

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           +I  +   D G Y C A N+YG    S  ++
Sbjct: 444 MIHNVNQSDAGMYQCLAENKYGAIYASAELK 474



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P     W KNGV L+  +R++         L I+++   D+G+Y C A N  G   ++A 
Sbjct: 417  PRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAE 472

Query: 2732 IKI 2734
            +KI
Sbjct: 473  LKI 475



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPV-GDPKLRVEWLRNGVPIE-ASNRLT 1760
            QDE +   PVF     DI    +      A    V G+P     WLRNG  I+  S+   
Sbjct: 91   QDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRY 150

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            ++ D  ++  N      +DSG Y C A N +G  ++
Sbjct: 151  SLIDGTFIISNPS--EAKDSGHYQCLATNTVGSILS 184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 10/128 (7%)

Query: 3416 KGKAPVFTVP----LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            +G+  V+T P      N   L  G    +E + T    P  +  W  NG  L   SR   
Sbjct: 381  RGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEM 438

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT 3531
                   +L I      D+G Y C A N YG    +A +K+         +QL K +  T
Sbjct: 439  VNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVT 494

Query: 3532 IDKIAALE 3539
             D+   +E
Sbjct: 495  KDQEVVIE 502



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 6/110 (5%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V T P ++ ++    ++    +R+EC+   K  P  R  W +NG  L    R   V  + 
Sbjct: 386  VYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV- 442

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
               L I  V   D+G Y C A N +G  +  A +           NQ+ +
Sbjct: 443  ---LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK 489



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLK+G P+   SR+          L I +V   DAG Y C A N  G    SA L I+  
Sbjct: 423  WLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILAS 478

Query: 1005 KDIIAESQ 1012
                A +Q
Sbjct: 479  APTFALNQ 486



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 13/106 (12%)

Query: 3556 NPPEFTTTPSDLILSENS---SAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            +PP   T  +D ++ E       HF   +     +++++E F  G P+ T + +K +N +
Sbjct: 282  SPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK-VNGY 340

Query: 3613 ---------GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                        +LEI  V   DAG+Y C+A N  G+ +   +LQV
Sbjct: 341  IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 386



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 12/157 (7%)

Query: 1960 DDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRP 2019
            ++SR K + +    V   P + + + + ++  G P+  E   T    PT R  W  NG P
Sbjct: 372  ENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVP 429

Query: 2020 VQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLY-LD 2078
            +    R +         L I      D G Y C A N  G    ++ +K+ A +  + L+
Sbjct: 430  LSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALN 485

Query: 2079 TLDEQRL-----KKIQELEKYERPKPIEEEQPGQRPV 2110
             L +  +     + + E +    PKP    + G R V
Sbjct: 486  QLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAV 522



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 33/122 (27%), Positives = 49/122 (40%), Gaps = 6/122 (4%)

Query: 1410 LESQHPSGLEKIQ-YLEDTSRYKKTDII--DESVTIKPRFVTRPKSIENVIEGQHVHFEC 1466
            L +  PS L   Q Y    + Y  +D    DESV   P FV  P  I    +        
Sbjct: 62   LSASSPSWLGAAQNYYSPINLYHSSDAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVAL 121

Query: 1467 KLEPVTDSNLKVEWFKNGQPVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525
              E   +      W +NG  + +   +R  + D  ++  +  +  A+DSG Y C A N V
Sbjct: 122  NCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSE--AKDSGHYQCLATNTV 179

Query: 1526 GT 1527
            G+
Sbjct: 180  GS 181



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 43/193 (22%), Positives = 70/193 (36%), Gaps = 12/193 (6%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            +  V + EGQ      S  P   + ++  W +N      +   R   +     L I   +
Sbjct: 202  RSAVSVREGQGVVLMCSPPPHSPE-IIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQ 260

Query: 3115 TTDSGTYSCRATNKWGQAEI-SVKLECVDKSKG----QKPRFTTHIQNIEGLKDGQSAHF 3169
            T+D G+Y C   N    A + S       ++ G     +P+   H         G +   
Sbjct: 261  TSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKM 320

Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229
            EC  +   +P   I W      +    R++        VL+I   Q  D+G Y CRA N 
Sbjct: 321  ECFAL--GNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIYECRAENS 374

Query: 3230 YGEDFTRATINCY 3242
             G++  R  +  Y
Sbjct: 375  RGKNSFRGQLQVY 387



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 7/92 (7%)

Query: 2908 YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFG 2967
            Y  P W+  +  + QL  G  L  E +   K  P  +  W  NG  L   SR ++ +   
Sbjct: 387  YTYPHWVEKLN-DTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG-- 441

Query: 2968 FVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
               L + +V + D+G+Y C A NK G  + S+
Sbjct: 442  --VLMIHNVNQSDAGMYQCLAENKYGAIYASA 471



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            ++  LN+     G  + +EC       PT +  W  N  PL   +R +  +      L I
Sbjct: 392  WVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV----LMI 445

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLR 2864
             +  + D+G+Y C A N  G+   S  L+
Sbjct: 446  HNVNQSDAGMYQCLAENKYGAIYASAELK 474



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 7/88 (7%)

Query: 70  SPPIF--EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           S P F   Q+ K     +      E K +G+P P +SW +    + E  + ++       
Sbjct: 478 SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAI-----LP 532

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           D SL I      DEG+Y C   N +G A
Sbjct: 533 DGSLRILNASKSDEGKYVCRGENVFGSA 560



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 3446 PTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505
            P   P   + W    ++++   R     D    IL  S +   D G+Y+CR  N +G A 
Sbjct: 505  PQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKS---DEGKYVCRGENVFGSAE 561

Query: 3506 TTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
              AS+ V+    I L    PK  E T+ +   L
Sbjct: 562  IIASLSVKEPTRIEL---TPKRTELTVGESIVL 591



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 6/120 (5%)

Query: 237 RESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPR 296
           + ++T   V      ++   D  +G   P      P      +G   + +    GNP P 
Sbjct: 272 KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 331

Query: 297 VTWFK-NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           +TW K NG   I S         +   L + N Q  D+G Y   AEN  G     G L V
Sbjct: 332 ITWMKVNG--YIPSKAR---LRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 39/188 (20%), Positives = 64/188 (34%), Gaps = 6/188 (3%)

Query: 3041 DDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
            D+     P F     DI+  ++        +    G+      W  NG  I+     R  
Sbjct: 92   DESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYS 151

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
               G  ++    ++  DSG Y C ATN  G    S+              F+   ++   
Sbjct: 152  LIDGTFIISN-PSEAKDSGHYQCLATNTVG----SILSREATLQFAYLGNFSGRTRSAVS 206

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            +++GQ     C+  P   P++   W  N  P   +   +         L I+  Q  D G
Sbjct: 207  VREGQGVVLMCS-PPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVG 265

Query: 3221 EYVCRAYN 3228
             Y+C   N
Sbjct: 266  SYICLVKN 273



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 7/87 (8%)

Query: 1177 PVFVQPLSNP--PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFG 1233
            PVFVQ   +   P  S+ K + L C  E  G+P     W  NG  + + S ++ +  D  
Sbjct: 99   PVFVQEPDDIIFPTDSDEKKVALNC--EVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT 156

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGS 1260
            F+  +   + + D+G Y   A N +GS
Sbjct: 157  FIISN--PSEAKDSGHYQCLATNTVGS 181



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL- 4680
            P +II P      ++ + +  +C++ G P+P+ +W +    I     ++ S     + + 
Sbjct: 105  PDDIIFPTD----SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIIS 160

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRV 4704
              SEA  +D G Y+C+A N+ G +
Sbjct: 161  NPSEA--KDSGHYQCLATNTVGSI 182



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            +G T   +C    +G+P   + W +    I   +R+ K+       + I +V+ +D G+Y
Sbjct: 314  KGTTVKMEC--FALGNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIY 367

Query: 2450 MCRASNLLGE 2459
             CRA N  G+
Sbjct: 368  ECRAENSRGK 377



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 5/87 (5%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V + Q V  ECK  P       + W K  + V    R   + D    +L I++    D G
Sbjct: 493  VTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 547

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
             Y CR  N+ G+ E+   L+ +  T I
Sbjct: 548  KYVCRGENVFGSAEIIASLSVKEPTRI 574



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 32/100 (32%), Positives = 42/100 (42%), Gaps = 10/100 (10%)

Query: 3817 SDAPKEEPIVSTPPKFITQ---IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL-- 3871
            SDA K++  V   P F+ +   I   T  + + V   C V     P  R  W RNG    
Sbjct: 86   SDAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYR--WLRNGTEID 143

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            L S +RY  +     +S       A+DSG Y C A N  G
Sbjct: 144  LESDYRYSLIDGTFIISNPS---EAKDSGHYQCLATNTVG 180



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 4111 PVFVSLPDAV---TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGMYH 4166
            PVFV  PD +   T  + +     C V G+P P   WL NG  I   S Y+ +  DG + 
Sbjct: 99   PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158

Query: 4167 FDIPKTRQYDTGKIEVI 4183
               P   + D+G  + +
Sbjct: 159  ISNPSEAK-DSGHYQCL 174



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)

Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
           ++ GNP P   W +NG  +   + +   +  + T +    ++  DSGHY  LA N  G I
Sbjct: 124 EVRGNPVPSYRWLRNGTEIDLESDYRY-SLIDGTFIISNPSEAKDSGHYQCLATNTVGSI 182

Query: 348 VT 349
           ++
Sbjct: 183 LS 184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 2518 SELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAND 2577
            ++L  G    +E +    G P   + W  NGV L   SR    +      L I++V  +D
Sbjct: 399  TQLDSGSPLRWECKAT--GKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSD 452

Query: 2578 AGLYMCKAINRAG 2590
            AG+Y C A N+ G
Sbjct: 453  AGMYQCLAENKYG 465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 1/94 (1%)

Query: 2635 DTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKST 2694
            D  V   P+F           +     +    E R +P     W +NG  +   +  + +
Sbjct: 92   DESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYS 151

Query: 2695 FDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
               G   +S N     DSG Y C ATN +G  +S
Sbjct: 152  LIDGTFIIS-NPSEAKDSGHYQCLATNTVGSILS 184



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 6/97 (6%)

Query: 2641 APIFTTH-LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            AP F  + LK    + + Q V +E +  P+  P   I W K    +    R+    D  L
Sbjct: 479  APTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDGSL 536

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              L+ +     D G Y C+  N+ G A   AS+ +++
Sbjct: 537  RILNASK---SDEGKYVCRGENVFGSAEIIASLSVKE 570


>BC039255-1|AAH39255.1|  617|Homo sapiens CNTN5 protein protein.
          Length = 617

 Score =  114 bits (274), Expect = 9e-24
 Identities = 106/383 (27%), Positives = 163/383 (42%), Gaps = 47/383 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P I W + N  I +    +     ++++L I  V ++D+ ++   AEN  G     
Sbjct: 32   GNPVPTITWMKVNGYIPSKARLR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFR 87

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKV 4554
              L V             P +     +  + SG  +R + K TG KP   Y WLKNG  +
Sbjct: 88   GQLQV----------YTYPHWVEKLNDTQLDSGSPLRWECKATG-KPRPTYRWLKNGVPL 136

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R +++       L+I      D+G Y+C+A N  G     AE  +           
Sbjct: 137  SPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI----------- 181

Query: 4615 QTKAANAPPEIIEPLKDK-IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                A+AP   +  LK   IV + Q +   CK  G P PT+ W KGD+ ++ +K   +  
Sbjct: 182  ---LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAI-- 236

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR-DIVV 4732
               + +LRI  A   DEG Y C   N  G   + A L V +P + +    LTP R ++ V
Sbjct: 237  -LPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE----LTPKRTELTV 291

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALI---PETPDFQMIH-EGNNAVLLIGNTYEEDT 4788
             E      K    + +  T  W  +G  I    E   F+ I  + ++A L+I N      
Sbjct: 292  GESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHA 351

Query: 4789 GTFTCRATTAAGQVETSAKLVVK 4811
            G + CR  T A  V   A+L+V+
Sbjct: 352  GRYGCRVQTTADSVSDEAELLVR 374



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 58/204 (28%), Positives = 89/204 (43%), Gaps = 10/204 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P +V+   D  +  G   R++C+ TG+P P   W  N   +      +++     N  LM
Sbjct: 96  PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV-----NGVLM 150

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I NV  SD+G+  C+A NK G       L ++      A   +++  T+ V + + VV+ 
Sbjct: 151 IHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK--TIIVTKDQEVVIE 208

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G+P P I+W+K    +  N  + I  DG   +L I  A  SD   Y C  +NV GS
Sbjct: 209 CKPQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEGKYVCRGENVFGS 265

Query: 572 TATRARLYXXXXXXXXXXQKRLHL 595
               A L            KR  L
Sbjct: 266 AEIIASLSVKEPTRIELTPKRTEL 289



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 75/292 (25%), Positives = 112/292 (38%), Gaps = 29/292 (9%)

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            V    G  V+++    G     + W+K    V   I +K         L I      D+G
Sbjct: 16   VTAAKGTTVKMECFALGNPVPTITWMK----VNGYIPSKARLRKSQAVLEIPNVQLDDAG 71

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             YEC A NS G               K+  + Q +    P   +E L D  +  G  + +
Sbjct: 72   IYECRAENSRG---------------KNSFRGQLQVYTYP-HWVEKLNDTQLDSGSPLRW 115

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
             CK  GKP PT +W K    + P    +M        L I      D G Y+C+A N  G
Sbjct: 116  ECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYG 171

Query: 4703 RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
             +  +A+LK+        L  L   + I+V + Q    + +     KPTI W +    + 
Sbjct: 172  AIYASAELKILASAPTFALNQLK--KTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVR 229

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            E     ++ +G+  +L   N  + D G + CR     G  E  A L VK  T
Sbjct: 230  ENKRIAILPDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIASLSVKEPT 278



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 53/174 (30%), Positives = 80/174 (45%), Gaps = 14/174 (8%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G   + +C   G P P +TW     ++      K  + +S    L I NV L D+G+  
Sbjct: 20  KGTTVKMECFALGNPVPTITWM----KVNGYIPSKARLRKS-QAVLEIPNVQLDDAGIYE 74

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C A N  G+ +F+ +L V        P +VE+ +   +  G P+    +A G P P   W
Sbjct: 75  CRAENSRGKNSFRGQLQVY-----TYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRW 129

Query: 525 QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            K+GVP+  +P+ R+    G   L I     SDA  YQC A+N  G+    A L
Sbjct: 130 LKNGVPL--SPQSRVEMVNG--VLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 179



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 80/313 (25%), Positives = 127/313 (40%), Gaps = 40/313 (12%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P + +K+   ++      R+E +  G+P P  +W +   P+  SP  ++       +L+I
Sbjct: 96   PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVE--MVNGVLMI 151

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT--AQNVNVTSG 4528
              V   D+ ++  +AEN+ G    SA L +             P+F L    + + VT  
Sbjct: 152  HNVNQSDAGMYQCLAENKYGAIYASAELKILAS---------APTFALNQLKKTIIVTKD 202

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            Q V ++ K  G+    + W K  + V+ + R  IL  DG  +L IL A   D GKY C  
Sbjct: 203  QEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL-PDG--SLRILNASKSDEGKYVCRG 259

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N  G     AE + SL       K  T+    P       K   +  G++I  +CK + 
Sbjct: 260  ENVFG----SAEIIASLSV-----KEPTRIELTP-------KRTELTVGESIVLNCKAIH 303

Query: 4649 KPLPTVQWY---KGDKL--IKPSKYFQMSRT-ADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                 V +Y   KG  +   +   +F+  R  A    L I        G Y C    +A 
Sbjct: 304  DASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTAD 363

Query: 4703 RVTVAAKLKVTQP 4715
             V+  A+L V  P
Sbjct: 364  SVSDEAELLVRGP 376



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 4/113 (3%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P   +K  +++L  G+  +++ + +G PRP   W KNG  L   ++ E++    +  L +
Sbjct: 96  PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV----NGVLMI 151

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378
            N  +SD+G Y  LAEN  G I  S  L + +   ++  +Q  + I  T+ +E
Sbjct: 152 HNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQE 204



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 50/192 (26%), Positives = 76/192 (39%), Gaps = 18/192 (9%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+    F   V  ++G     E   +  G+    I W      I +  R+R   A    V
Sbjct: 6    PKIEVHFPFTVTAAKGTTVKMECFAL--GNPVPTITWMKVNGYIPSKARLRKSQA----V 59

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   +  D+G Y CRA N  G+     +L+         P +   + + + L  G   
Sbjct: 60   LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVY-----TYPHWVEKLNDTQ-LDSGSPL 113

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             +EC       P  +  W  NG P+   +R++ V+     VL I      D+G Y C A 
Sbjct: 114  RWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAE 167

Query: 3228 NKYGEDFTRATI 3239
            NKYG  +  A +
Sbjct: 168  NKYGAIYASAEL 179



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 43/158 (27%), Positives = 60/158 (37%), Gaps = 14/158 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG       W  NG  +    R+  V      VL I     +D+G Y C A NK+G    
Sbjct: 120  TGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYA 175

Query: 3135 SVKLECVDKSKGQKPRFT-THIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            S +L    K     P F    ++    +   Q    EC   P   P   I W    + +R
Sbjct: 176  SAEL----KILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVR 229

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             + RI  + D    +L+       D G+YVCR  N +G
Sbjct: 230  ENKRIAILPDGSLRILN---ASKSDEGKYVCRGENVFG 264



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 6/92 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P +    +D  L   S   +EC+       + R  W  NG PL   SRV+ +N     +L
Sbjct: 96   PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VL 149

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I  V Q DAG+Y C A N++G    S +L++
Sbjct: 150  MIHNVNQSDAGMYQCLAENKYGAIYASAELKI 181



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDID 3758
            VE  ++  +  G P+ ++C+      PT R  W  NG P +  SRV  +N      L I 
Sbjct: 99   VEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VLMIH 152

Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
             +   DAG Y C A NK+G+   +A++   A       +QL + +   K +E+
Sbjct: 153  NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEV 205



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
           G+P+P ++W K G R +  NK   I      +LR+ N  KSD G Y    EN  G     
Sbjct: 213 GSPKPTISW-KKGDRAVRENKRIAILPDG--SLRILNASKSDEGKYVCRGENVFGSAEII 269

Query: 351 GYLAVESPTESYVQDQRSQ 369
             L+V+ PT   +  +R++
Sbjct: 270 ASLSVKEPTRIELTPKRTE 288



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 5/89 (5%)

Query: 491 PKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
           PK    F  T+   +G  V +   A+G P P ITW K    I     LR       + L+
Sbjct: 6   PKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLR----KSQAVLE 61

Query: 550 IPRAKASDAAWYQCTAQNVAGSTATRARL 578
           IP  +  DA  Y+C A+N  G  + R +L
Sbjct: 62  IPNVQLDDAGIYECRAENSRGKNSFRGQL 90



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 1701 SAQDEVITQAPVFTMPM--KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            SA+ +++  AP F +    K I V ++Q    E +  P G PK  + W +    +  + R
Sbjct: 176  SAELKILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKR 233

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
            +  + D     LN    +  D G Y CR  N  G A   ++L V+    ++L
Sbjct: 234  IAILPDGSLRILN---ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIEL 282



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 3819 APKEEPIVSTPPKF-ITQIKSHT-VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            A  E  I+++ P F + Q+K    V + + V  EC+  P+  PK  I W +  + +    
Sbjct: 175  ASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENK 232

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
            R   + D    SL IL     D G+Y+CR  N FG     A++S K+
Sbjct: 233  RIAILPDG---SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 276



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 7/101 (6%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P ++  L D  +L  G    +E + T    PT R  W K+G P++  SR+  +       
Sbjct: 96  PHWVEKLNDT-QLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV---- 148

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I ++   DAG Y   A NK G   ++A +++ A +   A
Sbjct: 149 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA 189



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 6/96 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P +   + D ++       +E +    G P+    WL+NGVP+   +R+  ++      L
Sbjct: 96   PHWVEKLNDTQLDSGSPLRWECKA--TGKPRPTYRWLKNGVPLSPQSRVEMVNG----VL 149

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +  VN  D+G Y C A N+ G    S+ L + + A
Sbjct: 150  MIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA 185



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 41/145 (28%), Positives = 62/145 (42%), Gaps = 18/145 (12%)

Query: 1801 FVQSKASLQLESQHESALQKIQQLEDSSRYQRREDV---------EVAVNQAPRFITQLN 1851
            ++ SKA L+ +SQ    +  +Q L+D+  Y+ R +          ++ V   P ++ +LN
Sbjct: 46   YIPSKARLR-KSQAVLEIPNVQ-LDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLN 103

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
              T+L  G    +EC+    P P  R  W  NG  L    R    N      L I  V  
Sbjct: 104  D-TQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVN----GVLMIHNVNQ 156

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNV 1936
             D+G Y C A N  G   +S  L +
Sbjct: 157  SDAGMYQCLAENKYGAIYASAELKI 181



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 1171 EISKSKPVF-VQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            +I  S P F +  L     V++ + + +EC+  P G P   + W    R+V    R    
Sbjct: 180  KILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAIL 237

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
             D    +L I++A+ +D G+Y  R  N  GSA   A + V E + I
Sbjct: 238  PDG---SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRI 280



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 3/82 (3%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           +P G P   I W K  +++  + R  +I   G  SL +L+ +  D G+Y CR  +  G A
Sbjct: 210 KPQGSPKPTISWKKGDRAVRENKRI-AILPDG--SLRILNASKSDEGKYVCRGENVFGSA 266

Query: 721 ETKAVLHVTPRATIERTSQHPE 742
           E  A L V     IE T +  E
Sbjct: 267 EIIASLSVKEPTRIELTPKRTE 288



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +   +G  +  EC    +  PT  I W   N  +PS  R +     S   L+I +   +D
Sbjct: 16   VTAAKGTTVKMECFALGNPVPT--ITWMKVNGYIPSKARLRK----SQAVLEIPNVQLDD 69

Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864
            +GIY C+A NS+G  +  G L+
Sbjct: 70   AGIYECRAENSRGKNSFRGQLQ 91



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/115 (27%), Positives = 46/115 (40%), Gaps = 6/115 (5%)

Query: 3695 PRFTV-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P F + ++K  I V +   V  +C+  P G P   I W    R      R+  L D    
Sbjct: 186  PTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDGSLR 243

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
             L+       D G+Y CR  N +GSA   A ++      I L  +  +   GE I
Sbjct: 244  ILNAS---KSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESI 295



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/120 (26%), Positives = 47/120 (39%), Gaps = 11/120 (9%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            P G     I W    + +  + RI  +   G   L IL    +D G Y CR  N +G AE
Sbjct: 211  PQGSPKPTISWKKGDRAVRENKRI-AILPDGS--LRILNASKSDEGKYVCRGENVFGSAE 267

Query: 3134 ISVKLECVDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            I   L   + ++ +  P+ T        L  G+S    C  +     D+   W   GQP+
Sbjct: 268  IIASLSVKEPTRIELTPKRTE-------LTVGESIVLNCKAIHDASLDVTFYWTLKGQPI 320



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 5/95 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + + Q    +C+  P G P   + W + ++ + ++ RI    D    S+ I +    DEG
Sbjct: 199  VTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 253

Query: 2448 VYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPE 2482
             Y+CR  N+ G               I+L  +  E
Sbjct: 254  KYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTE 288



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            +R     R  + V   P +   L++ +   G+ +  EC+       T R  W  NG P+ 
Sbjct: 80   SRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLS 137

Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
               R     E     L + +V   D+G+Y C A N+ G    S  L+++A
Sbjct: 138  PQSRV----EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILA 183



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 6/91 (6%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P + +   + +   G   ++E K  G P P   W +   PL   ++  M        V L
Sbjct: 96  PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM-----VNGV-L 149

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           +I  +   D G Y C A N+YG    S  ++
Sbjct: 150 MIHNVNQSDAGMYQCLAENKYGAIYASAELK 180



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P     W KNGV L+  +R++         L I+++   D+G+Y C A N  G   ++A 
Sbjct: 123  PRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAE 178

Query: 2732 IKI 2734
            +KI
Sbjct: 179  LKI 181



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 10/128 (7%)

Query: 3416 KGKAPVFTVP----LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            +G+  V+T P      N   L  G    +E + T    P  +  W  NG  L   SR   
Sbjct: 87   RGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEM 144

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT 3531
                   +L I      D+G Y C A N YG    +A +K+         +QL K +  T
Sbjct: 145  VNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVT 200

Query: 3532 IDKIAALE 3539
             D+   +E
Sbjct: 201  KDQEVVIE 208



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/113 (24%), Positives = 46/113 (40%), Gaps = 6/113 (5%)

Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
           +VY  P ++  L       G  + +E +    G P     WLKNG  +   SR   +   
Sbjct: 91  QVYTYPHWVEKLNDTQLDSGSPLRWECKA--TGKPRPTYRWLKNGVPLSPQSRVEMV--N 146

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
           G + +   ++N  D+G Y C A +  G     A L +   A     +Q  +T+
Sbjct: 147 GVLMIH--NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTI 197



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 6/110 (5%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V T P ++ ++    ++    +R+EC+   K  P  R  W +NG  L    R   V  + 
Sbjct: 92   VYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV- 148

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
               L I  V   D+G Y C A N +G  +  A +           NQ+ +
Sbjct: 149  ---LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK 195



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLK+G P+   SR+          L I +V   DAG Y C A N  G    SA L I+  
Sbjct: 129  WLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILAS 184

Query: 1005 KDIIAESQ 1012
                A +Q
Sbjct: 185  APTFALNQ 192



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 12/157 (7%)

Query: 1960 DDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRP 2019
            ++SR K + +    V   P + + + + ++  G P+  E   T    PT R  W  NG P
Sbjct: 78   ENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVP 135

Query: 2020 VQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLY-LD 2078
            +    R +         L I      D G Y C A N  G    ++ +K+ A +  + L+
Sbjct: 136  LSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALN 191

Query: 2079 TLDEQRL-----KKIQELEKYERPKPIEEEQPGQRPV 2110
             L +  +     + + E +    PKP    + G R V
Sbjct: 192  QLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAV 228



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 7/92 (7%)

Query: 2908 YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFG 2967
            Y  P W+  +  + QL  G  L  E +   K  P  +  W  NG  L   SR ++ +   
Sbjct: 93   YTYPHWVEKLN-DTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG-- 147

Query: 2968 FVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
               L + +V + D+G+Y C A NK G  + S+
Sbjct: 148  --VLMIHNVNQSDAGMYQCLAENKYGAIYASA 177



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            ++  LN+     G  + +EC       PT +  W  N  PL   +R +  +      L I
Sbjct: 98   WVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV----LMI 151

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLR 2864
             +  + D+G+Y C A N  G+   S  L+
Sbjct: 152  HNVNQSDAGMYQCLAENKYGAIYASAELK 180



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 7/88 (7%)

Query: 70  SPPIF--EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           S P F   Q+ K     +      E K +G+P P +SW +    + E  + ++       
Sbjct: 184 SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAI-----LP 238

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           D SL I      DEG+Y C   N +G A
Sbjct: 239 DGSLRILNASKSDEGKYVCRGENVFGSA 266



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 3446 PTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505
            P   P   + W    ++++   R     D    IL  S +   D G+Y+CR  N +G A 
Sbjct: 211  PQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKS---DEGKYVCRGENVFGSAE 267

Query: 3506 TTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
              AS+ V+    I L    PK  E T+ +   L
Sbjct: 268  IIASLSVKEPTRIEL---TPKRTELTVGESIVL 297



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            +G T   +C    +G+P   + W +    I   +R+ K+       + I +V+ +D G+Y
Sbjct: 20   KGTTVKMEC--FALGNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIY 73

Query: 2450 MCRASNLLGE 2459
             CRA N  G+
Sbjct: 74   ECRAENSRGK 83



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 5/87 (5%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V + Q V  ECK  P       + W K  + V    R   + D    +L I++    D G
Sbjct: 199  VTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 253

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
             Y CR  N+ G+ E+   L+ +  T I
Sbjct: 254  KYVCRGENVFGSAEIIASLSVKEPTRI 280



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 2518 SELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAND 2577
            ++L  G    +E +    G P   + W  NGV L   SR    +      L I++V  +D
Sbjct: 105  TQLDSGSPLRWECKAT--GKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSD 158

Query: 2578 AGLYMCKAINRAG 2590
            AG+Y C A N+ G
Sbjct: 159  AGMYQCLAENKYG 171



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 6/97 (6%)

Query: 2641 APIFTTH-LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            AP F  + LK    + + Q V +E +  P+  P   I W K    +    R+    D  L
Sbjct: 185  APTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDGSL 242

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              L+ +     D G Y C+  N+ G A   AS+ +++
Sbjct: 243  RILNASK---SDEGKYVCRGENVFGSAEIIASLSVKE 276


>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
          Length = 1026

 Score =  114 bits (274), Expect = 9e-24
 Identities = 106/383 (27%), Positives = 163/383 (42%), Gaps = 47/383 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P I W + N  I +    +     ++++L I  V ++D+ ++   AEN  G     
Sbjct: 252  GNPVPTITWMKVNGYIPSKARLR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFR 307

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKV 4554
              L V             P +     +  + SG  +R + K TG KP   Y WLKNG  +
Sbjct: 308  GQLQV----------YTYPHWVEKLNDTQLDSGSPLRWECKATG-KPRPTYRWLKNGVPL 356

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R +++       L+I      D+G Y+C+A N  G     AE  +           
Sbjct: 357  SPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI----------- 401

Query: 4615 QTKAANAPPEIIEPLKDK-IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                A+AP   +  LK   IV + Q +   CK  G P PT+ W KGD+ ++ +K   +  
Sbjct: 402  ---LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAI-- 456

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR-DIVV 4732
               + +LRI  A   DEG Y C   N  G   + A L V +P + +    LTP R ++ V
Sbjct: 457  -LPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE----LTPKRTELTV 511

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALI---PETPDFQMIH-EGNNAVLLIGNTYEEDT 4788
             E      K    + +  T  W  +G  I    E   F+ I  + ++A L+I N      
Sbjct: 512  GESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHA 571

Query: 4789 GTFTCRATTAAGQVETSAKLVVK 4811
            G + CR  T A  V   A+L+V+
Sbjct: 572  GRYGCRVQTTADSVSDEAELLVR 594



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 100/391 (25%), Positives = 159/391 (40%), Gaps = 34/391 (8%)

Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            + ++     E  G P+P  +W R    I    D++ ++    + +I      +DS  +  
Sbjct: 41   DEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYR-YSLIDGTFIISNPSEAKDSGHYQC 99

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543
            +A N  G+   S    ++        G        T   V+V  GQ V L        P 
Sbjct: 100  LATNTVGSI-LSREATLQFAYLGNFSG-------RTRSAVSVREGQGVVLMCSPPPHSPE 151

Query: 4544 DVY-WLKNG--KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             +Y W+ N     V  D R  I +E G   L I +    D G Y C+  N+   AR    
Sbjct: 152  IIYSWVFNEFPSFVAEDSRRFISQETGN--LYISKVQTSDVGSYICLVKNTVTNAR---- 205

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             V+S P               P   +        A+G  ++  C  +G P+PT+ W K +
Sbjct: 206  -VLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVN 264

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQAD 4719
              I PSK         +  L I     +D G Y+C A NS G+ +   +L+V T P   +
Sbjct: 265  GYI-PSK---ARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 320

Query: 4720 NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                   L D  +  G P +++ + T K +PT +WL+ G  +P +P  ++  E  N VL+
Sbjct: 321  K------LNDTQLDSGSPLRWECKATGKPRPTYRWLKNG--VPLSPQSRV--EMVNGVLM 370

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            I N  + D G + C A    G +  SA+L +
Sbjct: 371  IHNVNQSDAGMYQCLAENKYGAIYASAELKI 401



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 90/378 (23%), Positives = 137/378 (36%), Gaps = 30/378 (7%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P  +  W    FP   + D +         L I +V   D   +  + +N    A+  + 
Sbjct: 150  PEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSP 209

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ-NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
                  R  G  G   P   +     V    G  V+++    G     + W+K    V  
Sbjct: 210  PTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK----VNG 265

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
             I +K         L I      D+G YEC A NS G               K+  + Q 
Sbjct: 266  YIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRG---------------KNSFRGQL 310

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
            +    P   +E L D  +  G  + + CK  GKP PT +W K    + P    +M     
Sbjct: 311  QVYTYP-HWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG-- 367

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L I      D G Y+C+A N  G +  +A+LK+        L  L   + I+V + Q
Sbjct: 368  --VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLK--KTIIVTKDQ 423

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
                + +     KPTI W +    + E     ++ +G+  +L   N  + D G + CR  
Sbjct: 424  EVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRIL---NASKSDEGKYVCRGE 480

Query: 4797 TAAGQVETSAKLVVKSKT 4814
               G  E  A L VK  T
Sbjct: 481  NVFGSAEIIASLSVKEPT 498



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 58/204 (28%), Positives = 89/204 (43%), Gaps = 10/204 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P +V+   D  +  G   R++C+ TG+P P   W  N   +      +++     N  LM
Sbjct: 316 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV-----NGVLM 370

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I NV  SD+G+  C+A NK G       L ++      A   +++  T+ V + + VV+ 
Sbjct: 371 IHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK--TIIVTKDQEVVIE 428

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G+P P I+W+K    +  N  + I  DG   +L I  A  SD   Y C  +NV GS
Sbjct: 429 CKPQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEGKYVCRGENVFGS 485

Query: 572 TATRARLYXXXXXXXXXXQKRLHL 595
               A L            KR  L
Sbjct: 486 AEIIASLSVKEPTRIELTPKRTEL 509



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 53/174 (30%), Positives = 80/174 (45%), Gaps = 14/174 (8%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G   + +C   G P P +TW     ++      K  + +S    L I NV L D+G+  
Sbjct: 240 KGTTVKMECFALGNPVPTITWM----KVNGYIPSKARLRKS-QAVLEIPNVQLDDAGIYE 294

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C A N  G+ +F+ +L V        P +VE+ +   +  G P+    +A G P P   W
Sbjct: 295 CRAENSRGKNSFRGQLQVY-----TYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRW 349

Query: 525 QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            K+GVP+  +P+ R+    G   L I     SDA  YQC A+N  G+    A L
Sbjct: 350 LKNGVPL--SPQSRVEMVNG--VLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 399



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 80/313 (25%), Positives = 127/313 (40%), Gaps = 40/313 (12%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P + +K+   ++      R+E +  G+P P  +W +   P+  SP  ++       +L+I
Sbjct: 316  PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVE--MVNGVLMI 371

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT--AQNVNVTSG 4528
              V   D+ ++  +AEN+ G    SA L +             P+F L    + + VT  
Sbjct: 372  HNVNQSDAGMYQCLAENKYGAIYASAELKILAS---------APTFALNQLKKTIIVTKD 422

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            Q V ++ K  G+    + W K  + V+ + R  IL  DG  +L IL A   D GKY C  
Sbjct: 423  QEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL-PDG--SLRILNASKSDEGKYVCRG 479

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N  G     AE + SL       K  T+    P       K   +  G++I  +CK + 
Sbjct: 480  ENVFG----SAEIIASLSV-----KEPTRIELTP-------KRTELTVGESIVLNCKAIH 523

Query: 4649 KPLPTVQWY---KGDKL--IKPSKYFQMSRT-ADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                 V +Y   KG  +   +   +F+  R  A    L I        G Y C    +A 
Sbjct: 524  DASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTAD 583

Query: 4703 RVTVAAKLKVTQP 4715
             V+  A+L V  P
Sbjct: 584  SVSDEAELLVRGP 596



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 4/113 (3%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P   +K  +++L  G+  +++ + +G PRP   W KNG  L   ++ E++    +  L +
Sbjct: 316 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV----NGVLMI 371

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378
            N  +SD+G Y  LAEN  G I  S  L + +   ++  +Q  + I  T+ +E
Sbjct: 372 HNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQE 424



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 50/192 (26%), Positives = 76/192 (39%), Gaps = 18/192 (9%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+    F   V  ++G     E   +  G+    I W      I +  R+R   A    V
Sbjct: 226  PKIEVHFPFTVTAAKGTTVKMECFAL--GNPVPTITWMKVNGYIPSKARLRKSQA----V 279

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   +  D+G Y CRA N  G+     +L+         P +   + + + L  G   
Sbjct: 280  LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY-----PHWVEKLNDTQ-LDSGSPL 333

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             +EC       P  +  W  NG P+   +R++ V+     VL I      D+G Y C A 
Sbjct: 334  RWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAE 387

Query: 3228 NKYGEDFTRATI 3239
            NKYG  +  A +
Sbjct: 388  NKYGAIYASAEL 399



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 43/158 (27%), Positives = 60/158 (37%), Gaps = 14/158 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG       W  NG  +    R+  V      VL I     +D+G Y C A NK+G    
Sbjct: 340  TGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYA 395

Query: 3135 SVKLECVDKSKGQKPRFT-THIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            S +L    K     P F    ++    +   Q    EC   P   P   I W    + +R
Sbjct: 396  SAEL----KILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVR 449

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             + RI  + D    +L+       D G+YVCR  N +G
Sbjct: 450  ENKRIAILPDGSLRILN---ASKSDEGKYVCRGENVFG 484



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 49/170 (28%), Positives = 74/170 (43%), Gaps = 21/170 (12%)

Query: 421 PEV--TWFINDRQ--IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK------ 470
           PE+  +W  N+    + +D + + +  E+GN  L I+ V  SD G   C+ +N       
Sbjct: 150 PEIIYSWVFNEFPSFVAED-SRRFISQETGN--LYISKVQTSDVGSYICLVKNTVTNARV 206

Query: 471 -SGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            S  T    R + +  E    PK    F  T+   +G  V +   A+G P P ITW K  
Sbjct: 207 LSPPTPLTLRNDGVMGEY--EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVN 264

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I     LR       + L+IP  +  DA  Y+C A+N  G  + R +L
Sbjct: 265 GYIPSKARLR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQL 310



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 6/92 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P +    +D  L   S   +EC+       + R  W  NG PL   SRV+ +N     +L
Sbjct: 316  PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VL 369

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I  V Q DAG+Y C A N++G    S +L++
Sbjct: 370  MIHNVNQSDAGMYQCLAENKYGAIYASAELKI 401



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDID 3758
            VE  ++  +  G P+ ++C+      PT R  W  NG P +  SRV  +N      L I 
Sbjct: 319  VEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VLMIH 372

Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
             +   DAG Y C A NK+G+   +A++   A       +QL + +   K +E+
Sbjct: 373  NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEV 425



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
           G+P+P ++W K G R +  NK   I      +LR+ N  KSD G Y    EN  G     
Sbjct: 433 GSPKPTISW-KKGDRAVRENKRIAILPDG--SLRILNASKSDEGKYVCRGENVFGSAEII 489

Query: 351 GYLAVESPTESYVQDQRSQ 369
             L+V+ PT   +  +R++
Sbjct: 490 ASLSVKEPTRIELTPKRTE 508



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 1701 SAQDEVITQAPVFTMPM--KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            SA+ +++  AP F +    K I V ++Q    E +  P G PK  + W +    +  + R
Sbjct: 396  SAELKILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKR 453

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
            +  + D     LN    +  D G Y CR  N  G A   ++L V+    ++L
Sbjct: 454  IAILPDGSLRILN---ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIEL 502



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 3819 APKEEPIVSTPPKF-ITQIKSHT-VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            A  E  I+++ P F + Q+K    V + + V  EC+  P+  PK  I W +  + +    
Sbjct: 395  ASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENK 452

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
            R   + D    SL IL     D G+Y+CR  N FG     A++S K+
Sbjct: 453  RIAILPDG---SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 496



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 7/101 (6%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P ++  L D  +L  G    +E + T    PT R  W K+G P++  SR+  +       
Sbjct: 316 PHWVEKLNDT-QLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV---- 368

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I ++   DAG Y   A NK G   ++A +++ A +   A
Sbjct: 369 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA 409



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 26/184 (14%)

Query: 404 TEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVT-LSDS 460
           ++ K    +C V G P P   W  N  +I    DY + ++     +   +I+N +   DS
Sbjct: 40  SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLI-----DGTFIISNPSEAKDS 94

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-----STLNVREGEPVVLN-ARA 514
           G   C+A N  G        +++ +E  +   ++  F     S ++VREG+ VVL  +  
Sbjct: 95  GHYQCLATNTVG--------SILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 146

Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
             +P    +W  +  P     + R         L I + + SD   Y C  +N    T T
Sbjct: 147 PHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKN----TVT 202

Query: 575 RARL 578
            AR+
Sbjct: 203 NARV 206



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 6/96 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P +   + D ++       +E +    G P+    WL+NGVP+   +R+  ++      L
Sbjct: 316  PHWVEKLNDTQLDSGSPLRWECKA--TGKPRPTYRWLKNGVPLSPQSRVEMVNG----VL 369

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +  VN  D+G Y C A N+ G    S+ L + + A
Sbjct: 370  MIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA 405



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 41/145 (28%), Positives = 62/145 (42%), Gaps = 18/145 (12%)

Query: 1801 FVQSKASLQLESQHESALQKIQQLEDSSRYQRREDV---------EVAVNQAPRFITQLN 1851
            ++ SKA L+ +SQ    +  +Q L+D+  Y+ R +          ++ V   P ++ +LN
Sbjct: 266  YIPSKARLR-KSQAVLEIPNVQ-LDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLN 323

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
              T+L  G    +EC+    P P  R  W  NG  L    R    N      L I  V  
Sbjct: 324  D-TQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVN----GVLMIHNVNQ 376

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNV 1936
             D+G Y C A N  G   +S  L +
Sbjct: 377  SDAGMYQCLAENKYGAIYASAELKI 401



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 1171 EISKSKPVF-VQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            +I  S P F +  L     V++ + + +EC+  P G P   + W    R+V    R    
Sbjct: 400  KILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAIL 457

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
             D    +L I++A+ +D G+Y  R  N  GSA   A + V E + I
Sbjct: 458  PDG---SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRI 500



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 3/82 (3%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           +P G P   I W K  +++  + R  +I   G  SL +L+ +  D G+Y CR  +  G A
Sbjct: 430 KPQGSPKPTISWKKGDRAVRENKRI-AILPDG--SLRILNASKSDEGKYVCRGENVFGSA 486

Query: 721 ETKAVLHVTPRATIERTSQHPE 742
           E  A L V     IE T +  E
Sbjct: 487 EIIASLSVKEPTRIELTPKRTE 508



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +   +G  +  EC    +  PT  I W   N  +PS  R +     S   L+I +   +D
Sbjct: 236  VTAAKGTTVKMECFALGNPVPT--ITWMKVNGYIPSKARLRK----SQAVLEIPNVQLDD 289

Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864
            +GIY C+A NS+G  +  G L+
Sbjct: 290  AGIYECRAENSRGKNSFRGQLQ 311



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/115 (27%), Positives = 46/115 (40%), Gaps = 6/115 (5%)

Query: 3695 PRFTV-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P F + ++K  I V +   V  +C+  P G P   I W    R      R+  L D    
Sbjct: 406  PTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDGSLR 463

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
             L+       D G+Y CR  N +GSA   A ++      I L  +  +   GE I
Sbjct: 464  ILNAS---KSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESI 515



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/120 (26%), Positives = 47/120 (39%), Gaps = 11/120 (9%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            P G     I W    + +  + RI  +   G   L IL    +D G Y CR  N +G AE
Sbjct: 431  PQGSPKPTISWKKGDRAVRENKRI-AILPDGS--LRILNASKSDEGKYVCRGENVFGSAE 487

Query: 3134 ISVKLECVDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            I   L   + ++ +  P+ T        L  G+S    C  +     D+   W   GQP+
Sbjct: 488  IIASLSVKEPTRIELTPKRTE-------LTVGESIVLNCKAIHDASLDVTFYWTLKGQPI 540



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 5/95 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + + Q    +C+  P G P   + W + ++ + ++ RI    D    S+ I +    DEG
Sbjct: 419  VTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 473

Query: 2448 VYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPE 2482
             Y+CR  N+ G               I+L  +  E
Sbjct: 474  KYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTE 508



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 54/238 (22%), Positives = 86/238 (36%), Gaps = 23/238 (9%)

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
           V NAR +  PTP +T + DGV     P++ +H         +  AK +     +C A   
Sbjct: 201 VTNARVLSPPTP-LTLRNDGVMGEYEPKIEVHFP-----FTVTAAKGTTVKM-ECFALGN 253

Query: 569 AGSTATRARL--YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIP 626
              T T  ++  Y          Q  L +P                 Y    E +R    
Sbjct: 254 PVPTITWMKVNGYIPSKARLRKSQAVLEIPN--------VQLDDAGIYECRAENSRGKNS 305

Query: 627 PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686
              + +VY  P ++  L       G  + +E +    G P     WLKNG  +   SR  
Sbjct: 306 FRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKA--TGKPRPTYRWLKNGVPLSPQSRVE 363

Query: 687 SIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
            +   G + +   ++N  D+G Y C A +  G     A L +   A     +Q  +T+
Sbjct: 364 MV--NGVLMIH--NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTI 417



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            +R     R  + V   P +   L++ +   G+ +  EC+       T R  W  NG P+ 
Sbjct: 300  SRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLS 357

Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
               R     E     L + +V   D+G+Y C A N+ G    S  L+++A
Sbjct: 358  PQSRV----EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILA 403



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 6/91 (6%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P + +   + +   G   ++E K  G P P   W +   PL   ++  M        V L
Sbjct: 316 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM-----VNGV-L 369

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           +I  +   D G Y C A N+YG    S  ++
Sbjct: 370 MIHNVNQSDAGMYQCLAENKYGAIYASAELK 400



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P     W KNGV L+  +R++         L I+++   D+G+Y C A N  G   ++A 
Sbjct: 343  PRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAE 398

Query: 2732 IKI 2734
            +KI
Sbjct: 399  LKI 401



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 10/128 (7%)

Query: 3416 KGKAPVFTVP----LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            +G+  V+T P      N   L  G    +E + T    P  +  W  NG  L   SR   
Sbjct: 307  RGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEM 364

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT 3531
                   +L I      D+G Y C A N YG    +A +K+         +QL K +  T
Sbjct: 365  VNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVT 420

Query: 3532 IDKIAALE 3539
             D+   +E
Sbjct: 421  KDQEVVIE 428



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 6/110 (5%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V T P ++ ++    ++    +R+EC+   K  P  R  W +NG  L    R   V  + 
Sbjct: 312  VYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV- 368

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
               L I  V   D+G Y C A N +G  +  A +           NQ+ +
Sbjct: 369  ---LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK 415



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLK+G P+   SR+          L I +V   DAG Y C A N  G    SA L I+  
Sbjct: 349  WLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILAS 404

Query: 1005 KDIIAESQ 1012
                A +Q
Sbjct: 405  APTFALNQ 412



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 13/106 (12%)

Query: 3556 NPPEFTTTPSDLILSENS---SAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            +PP   T  +D ++ E       HF   +     +++++E F  G P+ T + +K +N +
Sbjct: 208  SPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK-VNGY 266

Query: 3613 ---------GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                        +LEI  V   DAG+Y C+A N  G+ +   +LQV
Sbjct: 267  IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 312



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 12/157 (7%)

Query: 1960 DDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRP 2019
            ++SR K + +    V   P + + + + ++  G P+  E   T    PT R  W  NG P
Sbjct: 298  ENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVP 355

Query: 2020 VQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLY-LD 2078
            +    R +         L I      D G Y C A N  G    ++ +K+ A +  + L+
Sbjct: 356  LSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALN 411

Query: 2079 TLDEQRL-----KKIQELEKYERPKPIEEEQPGQRPV 2110
             L +  +     + + E +    PKP    + G R V
Sbjct: 412  QLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAV 448



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 43/193 (22%), Positives = 70/193 (36%), Gaps = 12/193 (6%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            +  V + EGQ      S  P   + ++  W +N      +   R   +     L I   +
Sbjct: 128  RSAVSVREGQGVVLMCSPPPHSPE-IIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQ 186

Query: 3115 TTDSGTYSCRATNKWGQAEI-SVKLECVDKSKG----QKPRFTTHIQNIEGLKDGQSAHF 3169
            T+D G+Y C   N    A + S       ++ G     +P+   H         G +   
Sbjct: 187  TSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKM 246

Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229
            EC  +   +P   I W      +    R++        VL+I   Q  D+G Y CRA N 
Sbjct: 247  ECFAL--GNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIYECRAENS 300

Query: 3230 YGEDFTRATINCY 3242
             G++  R  +  Y
Sbjct: 301  RGKNSFRGQLQVY 313



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 7/92 (7%)

Query: 2908 YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFG 2967
            Y  P W+  +  + QL  G  L  E +   K  P  +  W  NG  L   SR ++ +   
Sbjct: 313  YTYPHWVEKLN-DTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG-- 367

Query: 2968 FVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
               L + +V + D+G+Y C A NK G  + S+
Sbjct: 368  --VLMIHNVNQSDAGMYQCLAENKYGAIYASA 397



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            ++  LN+     G  + +EC       PT +  W  N  PL   +R +  +      L I
Sbjct: 318  WVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV----LMI 371

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLR 2864
             +  + D+G+Y C A N  G+   S  L+
Sbjct: 372  HNVNQSDAGMYQCLAENKYGAIYASAELK 400



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 7/88 (7%)

Query: 70  SPPIF--EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           S P F   Q+ K     +      E K +G+P P +SW +    + E  + ++       
Sbjct: 404 SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAI-----LP 458

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           D SL I      DEG+Y C   N +G A
Sbjct: 459 DGSLRILNASKSDEGKYVCRGENVFGSA 486



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 3446 PTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505
            P   P   + W    ++++   R     D    IL  S +   D G+Y+CR  N +G A 
Sbjct: 431  PQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKS---DEGKYVCRGENVFGSAE 487

Query: 3506 TTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
              AS+ V+    I L    PK  E T+ +   L
Sbjct: 488  IIASLSVKEPTRIEL---TPKRTELTVGESIVL 517



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 6/120 (5%)

Query: 237 RESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPR 296
           + ++T   V      ++   D  +G   P      P      +G   + +    GNP P 
Sbjct: 198 KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 257

Query: 297 VTWFK-NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           +TW K NG   I S         +   L + N Q  D+G Y   AEN  G     G L V
Sbjct: 258 ITWMKVNG--YIPSKAR---LRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 312



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 7/87 (8%)

Query: 1177 PVFVQPLSNP--PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFG 1233
            PVFVQ   +   P  S+ K + L C  E  G+P     W  NG  + + S ++ +  D  
Sbjct: 25   PVFVQEPDDIIFPTDSDEKKVALNC--EVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT 82

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGS 1260
            F+  +   + + D+G Y   A N +GS
Sbjct: 83   FIISN--PSEAKDSGHYQCLATNTVGS 107



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL- 4680
            P +II P      ++ + +  +C++ G P+P+ +W +    I     ++ S     + + 
Sbjct: 31   PDDIIFPTD----SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIIS 86

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRV 4704
              SEA  +D G Y+C+A N+ G +
Sbjct: 87   NPSEA--KDSGHYQCLATNTVGSI 108



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            +G T   +C    +G+P   + W +    I   +R+ K+       + I +V+ +D G+Y
Sbjct: 240  KGTTVKMEC--FALGNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIY 293

Query: 2450 MCRASNLLGE 2459
             CRA N  G+
Sbjct: 294  ECRAENSRGK 303



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 5/87 (5%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V + Q V  ECK  P       + W K  + V    R   + D    +L I++    D G
Sbjct: 419  VTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 473

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
             Y CR  N+ G+ E+   L+ +  T I
Sbjct: 474  KYVCRGENVFGSAEIIASLSVKEPTRI 500



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 4111 PVFVSLPDAV---TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGMYH 4166
            PVFV  PD +   T  + +     C V G+P P   WL NG  I   S Y+ +  DG + 
Sbjct: 25   PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 84

Query: 4167 FDIPKTRQYDTGKIEVI 4183
               P   + D+G  + +
Sbjct: 85   ISNPSEAK-DSGHYQCL 100



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)

Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
           ++ GNP P   W +NG  +   + +   +  + T +    ++  DSGHY  LA N  G I
Sbjct: 50  EVRGNPVPSYRWLRNGTEIDLESDYRY-SLIDGTFIISNPSEAKDSGHYQCLATNTVGSI 108

Query: 348 VT 349
           ++
Sbjct: 109 LS 110



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/145 (22%), Positives = 52/145 (35%), Gaps = 6/145 (4%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W  NG  I+     R     G  ++    ++  DSG Y C ATN  G    S+       
Sbjct: 61   WLRNGTEIDLESDYRYSLIDGTFIISN-PSEAKDSGHYQCLATNTVG----SILSREATL 115

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
                   F+   ++   +++GQ     C+  P   P++   W  N  P   +   +    
Sbjct: 116  QFAYLGNFSGRTRSAVSVREGQGVVLMCS-PPPHSPEIIYSWVFNEFPSFVAEDSRRFIS 174

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYN 3228
                 L I+  Q  D G Y+C   N
Sbjct: 175  QETGNLYISKVQTSDVGSYICLVKN 199



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 2518 SELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAND 2577
            ++L  G    +E +    G P   + W  NGV L   SR    +      L I++V  +D
Sbjct: 325  TQLDSGSPLRWECKAT--GKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSD 378

Query: 2578 AGLYMCKAINRAG 2590
            AG+Y C A N+ G
Sbjct: 379  AGMYQCLAENKYG 391



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 6/97 (6%)

Query: 2641 APIFTTH-LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            AP F  + LK    + + Q V +E +  P+  P   I W K    +    R+    D  L
Sbjct: 405  APTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDGSL 462

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              L+ +     D G Y C+  N+ G A   AS+ +++
Sbjct: 463  RILNASK---SDEGKYVCRGENVFGSAEIIASLSVKE 496


>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
          Length = 1100

 Score =  114 bits (274), Expect = 9e-24
 Identities = 106/383 (27%), Positives = 163/383 (42%), Gaps = 47/383 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P I W + N  I +    +     ++++L I  V ++D+ ++   AEN  G     
Sbjct: 326  GNPVPTITWMKVNGYIPSKARLR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFR 381

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKV 4554
              L V             P +     +  + SG  +R + K TG KP   Y WLKNG  +
Sbjct: 382  GQLQV----------YTYPHWVEKLNDTQLDSGSPLRWECKATG-KPRPTYRWLKNGVPL 430

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R +++       L+I      D+G Y+C+A N  G     AE  +           
Sbjct: 431  SPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI----------- 475

Query: 4615 QTKAANAPPEIIEPLKDK-IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                A+AP   +  LK   IV + Q +   CK  G P PT+ W KGD+ ++ +K   +  
Sbjct: 476  ---LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAI-- 530

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR-DIVV 4732
               + +LRI  A   DEG Y C   N  G   + A L V +P + +    LTP R ++ V
Sbjct: 531  -LPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE----LTPKRTELTV 585

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALI---PETPDFQMIH-EGNNAVLLIGNTYEEDT 4788
             E      K    + +  T  W  +G  I    E   F+ I  + ++A L+I N      
Sbjct: 586  GESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHA 645

Query: 4789 GTFTCRATTAAGQVETSAKLVVK 4811
            G + CR  T A  V   A+L+V+
Sbjct: 646  GRYGCRVQTTADSVSDEAELLVR 668



 Score = 95.1 bits (226), Expect = 6e-18
 Identities = 100/391 (25%), Positives = 159/391 (40%), Gaps = 34/391 (8%)

Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            + ++     E  G P+P  +W R    I    D++ ++    + +I      +DS  +  
Sbjct: 115  DEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYR-YSLIDGTFIISNPSEAKDSGHYQC 173

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543
            +A N  G+   S    ++        G        T   V+V  GQ V L        P 
Sbjct: 174  LATNTVGSI-LSREATLQFAYLGNFSG-------RTRSAVSVREGQGVVLMCSPPPHSPE 225

Query: 4544 DVY-WLKNG--KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             +Y W+ N     V  D R  I +E G   L I +    D G Y C+  N+   AR    
Sbjct: 226  IIYSWVFNEFPSFVAEDSRRFISQETGN--LYISKVQTSDVGSYICLVKNTVTNAR---- 279

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             V+S P               P   +        A+G  ++  C  +G P+PT+ W K +
Sbjct: 280  -VLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVN 338

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQAD 4719
              I PSK         +  L I     +D G Y+C A NS G+ +   +L+V T P   +
Sbjct: 339  GYI-PSK---ARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 394

Query: 4720 NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
                   L D  +  G P +++ + T K +PT +WL+ G  +P +P  ++  E  N VL+
Sbjct: 395  K------LNDTQLDSGSPLRWECKATGKPRPTYRWLKNG--VPLSPQSRV--EMVNGVLM 444

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            I N  + D G + C A    G +  SA+L +
Sbjct: 445  IHNVNQSDAGMYQCLAENKYGAIYASAELKI 475



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 90/378 (23%), Positives = 137/378 (36%), Gaps = 30/378 (7%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P  +  W    FP   + D +         L I +V   D   +  + +N    A+  + 
Sbjct: 224  PEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSP 283

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQ-NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
                  R  G  G   P   +     V    G  V+++    G     + W+K    V  
Sbjct: 284  PTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK----VNG 339

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
             I +K         L I      D+G YEC A NS G               K+  + Q 
Sbjct: 340  YIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRG---------------KNSFRGQL 384

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
            +    P   +E L D  +  G  + + CK  GKP PT +W K    + P    +M     
Sbjct: 385  QVYTYP-HWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNG-- 441

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L I      D G Y+C+A N  G +  +A+LK+        L  L   + I+V + Q
Sbjct: 442  --VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLK--KTIIVTKDQ 497

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
                + +     KPTI W +    + E     ++ +G+  +L   N  + D G + CR  
Sbjct: 498  EVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRIL---NASKSDEGKYVCRGE 554

Query: 4797 TAAGQVETSAKLVVKSKT 4814
               G  E  A L VK  T
Sbjct: 555  NVFGSAEIIASLSVKEPT 572



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 58/204 (28%), Positives = 89/204 (43%), Gaps = 10/204 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P +V+   D  +  G   R++C+ TG+P P   W  N   +      +++     N  LM
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV-----NGVLM 444

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I NV  SD+G+  C+A NK G       L ++      A   +++  T+ V + + VV+ 
Sbjct: 445 IHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK--TIIVTKDQEVVIE 502

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +  G+P P I+W+K    +  N  + I  DG   +L I  A  SD   Y C  +NV GS
Sbjct: 503 CKPQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEGKYVCRGENVFGS 559

Query: 572 TATRARLYXXXXXXXXXXQKRLHL 595
               A L            KR  L
Sbjct: 560 AEIIASLSVKEPTRIELTPKRTEL 583



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 53/174 (30%), Positives = 80/174 (45%), Gaps = 14/174 (8%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G   + +C   G P P +TW     ++      K  + +S    L I NV L D+G+  
Sbjct: 314 KGTTVKMECFALGNPVPTITWM----KVNGYIPSKARLRKS-QAVLEIPNVQLDDAGIYE 368

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C A N  G+ +F+ +L V        P +VE+ +   +  G P+    +A G P P   W
Sbjct: 369 CRAENSRGKNSFRGQLQVY-----TYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRW 423

Query: 525 QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            K+GVP+  +P+ R+    G   L I     SDA  YQC A+N  G+    A L
Sbjct: 424 LKNGVPL--SPQSRVEMVNG--VLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 473



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 80/313 (25%), Positives = 127/313 (40%), Gaps = 40/313 (12%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P + +K+   ++      R+E +  G+P P  +W +   P+  SP  ++       +L+I
Sbjct: 390  PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVE--MVNGVLMI 445

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT--AQNVNVTSG 4528
              V   D+ ++  +AEN+ G    SA L +             P+F L    + + VT  
Sbjct: 446  HNVNQSDAGMYQCLAENKYGAIYASAELKILAS---------APTFALNQLKKTIIVTKD 496

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            Q V ++ K  G+    + W K  + V+ + R  IL  DG  +L IL A   D GKY C  
Sbjct: 497  QEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL-PDG--SLRILNASKSDEGKYVCRG 553

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N  G     AE + SL       K  T+    P       K   +  G++I  +CK + 
Sbjct: 554  ENVFG----SAEIIASLSV-----KEPTRIELTP-------KRTELTVGESIVLNCKAIH 597

Query: 4649 KPLPTVQWY---KGDKL--IKPSKYFQMSRT-ADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                 V +Y   KG  +   +   +F+  R  A    L I        G Y C    +A 
Sbjct: 598  DASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTAD 657

Query: 4703 RVTVAAKLKVTQP 4715
             V+  A+L V  P
Sbjct: 658  SVSDEAELLVRGP 670



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 4/113 (3%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P   +K  +++L  G+  +++ + +G PRP   W KNG  L   ++ E++    +  L +
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV----NGVLMI 445

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378
            N  +SD+G Y  LAEN  G I  S  L + +   ++  +Q  + I  T+ +E
Sbjct: 446 HNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQE 498



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 50/192 (26%), Positives = 76/192 (39%), Gaps = 18/192 (9%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+    F   V  ++G     E   +  G+    I W      I +  R+R   A    V
Sbjct: 300  PKIEVHFPFTVTAAKGTTVKMECFAL--GNPVPTITWMKVNGYIPSKARLRKSQA----V 353

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   +  D+G Y CRA N  G+     +L+         P +   + + + L  G   
Sbjct: 354  LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY-----PHWVEKLNDTQ-LDSGSPL 407

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             +EC       P  +  W  NG P+   +R++ V+     VL I      D+G Y C A 
Sbjct: 408  RWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAE 461

Query: 3228 NKYGEDFTRATI 3239
            NKYG  +  A +
Sbjct: 462  NKYGAIYASAEL 473



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 43/158 (27%), Positives = 60/158 (37%), Gaps = 14/158 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG       W  NG  +    R+  V      VL I     +D+G Y C A NK+G    
Sbjct: 414  TGKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYA 469

Query: 3135 SVKLECVDKSKGQKPRFT-THIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            S +L    K     P F    ++    +   Q    EC   P   P   I W    + +R
Sbjct: 470  SAEL----KILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVR 523

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             + RI  + D    +L+       D G+YVCR  N +G
Sbjct: 524  ENKRIAILPDGSLRILN---ASKSDEGKYVCRGENVFG 558



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 49/170 (28%), Positives = 74/170 (43%), Gaps = 21/170 (12%)

Query: 421 PEV--TWFINDRQ--IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK------ 470
           PE+  +W  N+    + +D + + +  E+GN  L I+ V  SD G   C+ +N       
Sbjct: 224 PEIIYSWVFNEFPSFVAED-SRRFISQETGN--LYISKVQTSDVGSYICLVKNTVTNARV 280

Query: 471 -SGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            S  T    R + +  E    PK    F  T+   +G  V +   A+G P P ITW K  
Sbjct: 281 LSPPTPLTLRNDGVMGEY--EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVN 338

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I     LR       + L+IP  +  DA  Y+C A+N  G  + R +L
Sbjct: 339 GYIPSKARLR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQL 384



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 6/92 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P +    +D  L   S   +EC+       + R  W  NG PL   SRV+ +N     +L
Sbjct: 390  PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VL 443

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I  V Q DAG+Y C A N++G    S +L++
Sbjct: 444  MIHNVNQSDAGMYQCLAENKYGAIYASAELKI 475



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDID 3758
            VE  ++  +  G P+ ++C+      PT R  W  NG P +  SRV  +N      L I 
Sbjct: 393  VEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG----VLMIH 446

Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
             +   DAG Y C A NK+G+   +A++   A       +QL + +   K +E+
Sbjct: 447  NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEV 499



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
           G+P+P ++W K G R +  NK   I      +LR+ N  KSD G Y    EN  G     
Sbjct: 507 GSPKPTISW-KKGDRAVRENKRIAILPDG--SLRILNASKSDEGKYVCRGENVFGSAEII 563

Query: 351 GYLAVESPTESYVQDQRSQ 369
             L+V+ PT   +  +R++
Sbjct: 564 ASLSVKEPTRIELTPKRTE 582



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 1701 SAQDEVITQAPVFTMPM--KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            SA+ +++  AP F +    K I V ++Q    E +  P G PK  + W +    +  + R
Sbjct: 470  SAELKILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKR 527

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
            +  + D     LN    +  D G Y CR  N  G A   ++L V+    ++L
Sbjct: 528  IAILPDGSLRILN---ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIEL 576



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 7/107 (6%)

Query: 3819 APKEEPIVSTPPKF-ITQIKSHT-VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
            A  E  I+++ P F + Q+K    V + + V  EC+  P+  PK  I W +  + +    
Sbjct: 469  ASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENK 526

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
            R   + D    SL IL     D G+Y+CR  N FG     A++S K+
Sbjct: 527  RIAILPDG---SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 570



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 7/101 (6%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P ++  L D  +L  G    +E + T    PT R  W K+G P++  SR+  +       
Sbjct: 390 PHWVEKLNDT-QLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV---- 442

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I ++   DAG Y   A NK G   ++A +++ A +   A
Sbjct: 443 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA 483



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 26/184 (14%)

Query: 404 TEGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVT-LSDS 460
           ++ K    +C V G P P   W  N  +I    DY + ++     +   +I+N +   DS
Sbjct: 114 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLI-----DGTFIISNPSEAKDS 168

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-----STLNVREGEPVVLN-ARA 514
           G   C+A N  G        +++ +E  +   ++  F     S ++VREG+ VVL  +  
Sbjct: 169 GHYQCLATNTVG--------SILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 220

Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
             +P    +W  +  P     + R         L I + + SD   Y C  +N    T T
Sbjct: 221 PHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKN----TVT 276

Query: 575 RARL 578
            AR+
Sbjct: 277 NARV 280



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 6/96 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P +   + D ++       +E +    G P+    WL+NGVP+   +R+  ++      L
Sbjct: 390  PHWVEKLNDTQLDSGSPLRWECKA--TGKPRPTYRWLKNGVPLSPQSRVEMVNG----VL 443

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +  VN  D+G Y C A N+ G    S+ L + + A
Sbjct: 444  MIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA 479



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 41/145 (28%), Positives = 62/145 (42%), Gaps = 18/145 (12%)

Query: 1801 FVQSKASLQLESQHESALQKIQQLEDSSRYQRREDV---------EVAVNQAPRFITQLN 1851
            ++ SKA L+ +SQ    +  +Q L+D+  Y+ R +          ++ V   P ++ +LN
Sbjct: 340  YIPSKARLR-KSQAVLEIPNVQ-LDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLN 397

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
              T+L  G    +EC+    P P  R  W  NG  L    R    N      L I  V  
Sbjct: 398  D-TQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVN----GVLMIHNVNQ 450

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNV 1936
             D+G Y C A N  G   +S  L +
Sbjct: 451  SDAGMYQCLAENKYGAIYASAELKI 475



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 1171 EISKSKPVF-VQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            +I  S P F +  L     V++ + + +EC+  P G P   + W    R+V    R    
Sbjct: 474  KILASAPTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAIL 531

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
             D    +L I++A+ +D G+Y  R  N  GSA   A + V E + I
Sbjct: 532  PDG---SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRI 574



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 3/82 (3%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           +P G P   I W K  +++  + R  +I   G  SL +L+ +  D G+Y CR  +  G A
Sbjct: 504 KPQGSPKPTISWKKGDRAVRENKRI-AILPDG--SLRILNASKSDEGKYVCRGENVFGSA 560

Query: 721 ETKAVLHVTPRATIERTSQHPE 742
           E  A L V     IE T +  E
Sbjct: 561 EIIASLSVKEPTRIELTPKRTE 582



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +   +G  +  EC    +  PT  I W   N  +PS  R +     S   L+I +   +D
Sbjct: 310  VTAAKGTTVKMECFALGNPVPT--ITWMKVNGYIPSKARLRK----SQAVLEIPNVQLDD 363

Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864
            +GIY C+A NS+G  +  G L+
Sbjct: 364  AGIYECRAENSRGKNSFRGQLQ 385



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/115 (27%), Positives = 46/115 (40%), Gaps = 6/115 (5%)

Query: 3695 PRFTV-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P F + ++K  I V +   V  +C+  P G P   I W    R      R+  L D    
Sbjct: 480  PTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDGSLR 537

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
             L+       D G+Y CR  N +GSA   A ++      I L  +  +   GE I
Sbjct: 538  ILNAS---KSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESI 589



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/120 (26%), Positives = 47/120 (39%), Gaps = 11/120 (9%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            P G     I W    + +  + RI  +   G   L IL    +D G Y CR  N +G AE
Sbjct: 505  PQGSPKPTISWKKGDRAVRENKRI-AILPDGS--LRILNASKSDEGKYVCRGENVFGSAE 561

Query: 3134 ISVKLECVDKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
            I   L   + ++ +  P+ T        L  G+S    C  +     D+   W   GQP+
Sbjct: 562  IIASLSVKEPTRIELTPKRTE-------LTVGESIVLNCKAIHDASLDVTFYWTLKGQPI 614



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 5/95 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + + Q    +C+  P G P   + W + ++ + ++ RI    D    S+ I +    DEG
Sbjct: 493  VTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 547

Query: 2448 VYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPE 2482
             Y+CR  N+ G               I+L  +  E
Sbjct: 548  KYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTE 582



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 54/238 (22%), Positives = 86/238 (36%), Gaps = 23/238 (9%)

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
           V NAR +  PTP +T + DGV     P++ +H         +  AK +     +C A   
Sbjct: 275 VTNARVLSPPTP-LTLRNDGVMGEYEPKIEVHFP-----FTVTAAKGTTVKM-ECFALGN 327

Query: 569 AGSTATRARL--YXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIP 626
              T T  ++  Y          Q  L +P                 Y    E +R    
Sbjct: 328 PVPTITWMKVNGYIPSKARLRKSQAVLEIPN--------VQLDDAGIYECRAENSRGKNS 379

Query: 627 PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686
              + +VY  P ++  L       G  + +E +    G P     WLKNG  +   SR  
Sbjct: 380 FRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKA--TGKPRPTYRWLKNGVPLSPQSRVE 437

Query: 687 SIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
            +   G + +   ++N  D+G Y C A +  G     A L +   A     +Q  +T+
Sbjct: 438 MV--NGVLMIH--NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTI 491



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            +R     R  + V   P +   L++ +   G+ +  EC+       T R  W  NG P+ 
Sbjct: 374  SRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLS 431

Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
               R     E     L + +V   D+G+Y C A N+ G    S  L+++A
Sbjct: 432  PQSRV----EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILA 477



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 6/91 (6%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P + +   + +   G   ++E K  G P P   W +   PL   ++  M        V L
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM-----VNGV-L 443

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           +I  +   D G Y C A N+YG    S  ++
Sbjct: 444 MIHNVNQSDAGMYQCLAENKYGAIYASAELK 474



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P     W KNGV L+  +R++         L I+++   D+G+Y C A N  G   ++A 
Sbjct: 417  PRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAE 472

Query: 2732 IKI 2734
            +KI
Sbjct: 473  LKI 475



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPV-GDPKLRVEWLRNGVPIE-ASNRLT 1760
            QDE +   PVF     DI    +      A    V G+P     WLRNG  I+  S+   
Sbjct: 91   QDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRY 150

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            ++ D  ++  N      +DSG Y C A N +G  ++
Sbjct: 151  SLIDGTFIISNPS--EAKDSGHYQCLATNTVGSILS 184



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 10/128 (7%)

Query: 3416 KGKAPVFTVP----LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            +G+  V+T P      N   L  G    +E + T    P  +  W  NG  L   SR   
Sbjct: 381  RGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEM 438

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT 3531
                   +L I      D+G Y C A N YG    +A +K+         +QL K +  T
Sbjct: 439  VNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVT 494

Query: 3532 IDKIAALE 3539
             D+   +E
Sbjct: 495  KDQEVVIE 502



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 6/110 (5%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V T P ++ ++    ++    +R+EC+   K  P  R  W +NG  L    R   V  + 
Sbjct: 386  VYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV- 442

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
               L I  V   D+G Y C A N +G  +  A +           NQ+ +
Sbjct: 443  ---LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK 489



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            WLK+G P+   SR+          L I +V   DAG Y C A N  G    SA L I+  
Sbjct: 423  WLKNGVPLSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILAS 478

Query: 1005 KDIIAESQ 1012
                A +Q
Sbjct: 479  APTFALNQ 486



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 13/106 (12%)

Query: 3556 NPPEFTTTPSDLILSENS---SAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            +PP   T  +D ++ E       HF   +     +++++E F  G P+ T + +K +N +
Sbjct: 282  SPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK-VNGY 340

Query: 3613 ---------GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                        +LEI  V   DAG+Y C+A N  G+ +   +LQV
Sbjct: 341  IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 386



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 12/157 (7%)

Query: 1960 DDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRP 2019
            ++SR K + +    V   P + + + + ++  G P+  E   T    PT R  W  NG P
Sbjct: 372  ENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVP 429

Query: 2020 VQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLY-LD 2078
            +    R +         L I      D G Y C A N  G    ++ +K+ A +  + L+
Sbjct: 430  LSPQSRVEMVNG----VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALN 485

Query: 2079 TLDEQRL-----KKIQELEKYERPKPIEEEQPGQRPV 2110
             L +  +     + + E +    PKP    + G R V
Sbjct: 486  QLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAV 522



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 33/122 (27%), Positives = 49/122 (40%), Gaps = 6/122 (4%)

Query: 1410 LESQHPSGLEKIQ-YLEDTSRYKKTDII--DESVTIKPRFVTRPKSIENVIEGQHVHFEC 1466
            L +  PS L   Q Y    + Y  +D    DESV   P FV  P  I    +        
Sbjct: 62   LSASSPSWLGAAQNYYSPINLYHSSDAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVAL 121

Query: 1467 KLEPVTDSNLKVEWFKNGQPVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525
              E   +      W +NG  + +   +R  + D  ++  +  +  A+DSG Y C A N V
Sbjct: 122  NCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSE--AKDSGHYQCLATNTV 179

Query: 1526 GT 1527
            G+
Sbjct: 180  GS 181



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 43/193 (22%), Positives = 70/193 (36%), Gaps = 12/193 (6%)

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTK 3114
            +  V + EGQ      S  P   + ++  W +N      +   R   +     L I   +
Sbjct: 202  RSAVSVREGQGVVLMCSPPPHSPE-IIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQ 260

Query: 3115 TTDSGTYSCRATNKWGQAEI-SVKLECVDKSKG----QKPRFTTHIQNIEGLKDGQSAHF 3169
            T+D G+Y C   N    A + S       ++ G     +P+   H         G +   
Sbjct: 261  TSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKM 320

Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229
            EC  +   +P   I W      +    R++        VL+I   Q  D+G Y CRA N 
Sbjct: 321  ECFAL--GNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIYECRAENS 374

Query: 3230 YGEDFTRATINCY 3242
             G++  R  +  Y
Sbjct: 375  RGKNSFRGQLQVY 387



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 7/92 (7%)

Query: 2908 YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFG 2967
            Y  P W+  +  + QL  G  L  E +   K  P  +  W  NG  L   SR ++ +   
Sbjct: 387  YTYPHWVEKLN-DTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNG-- 441

Query: 2968 FVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
               L + +V + D+G+Y C A NK G  + S+
Sbjct: 442  --VLMIHNVNQSDAGMYQCLAENKYGAIYASA 471



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            ++  LN+     G  + +EC       PT +  W  N  PL   +R +  +      L I
Sbjct: 392  WVEKLNDTQLDSGSPLRWECKATGKPRPTYR--WLKNGVPLSPQSRVEMVNGV----LMI 445

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLR 2864
             +  + D+G+Y C A N  G+   S  L+
Sbjct: 446  HNVNQSDAGMYQCLAENKYGAIYASAELK 474



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 7/88 (7%)

Query: 70  SPPIF--EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           S P F   Q+ K     +      E K +G+P P +SW +    + E  + ++       
Sbjct: 478 SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAI-----LP 532

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           D SL I      DEG+Y C   N +G A
Sbjct: 533 DGSLRILNASKSDEGKYVCRGENVFGSA 560



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 3446 PTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505
            P   P   + W    ++++   R     D    IL  S +   D G+Y+CR  N +G A 
Sbjct: 505  PQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKS---DEGKYVCRGENVFGSAE 561

Query: 3506 TTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
              AS+ V+    I L    PK  E T+ +   L
Sbjct: 562  IIASLSVKEPTRIEL---TPKRTELTVGESIVL 591



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 6/120 (5%)

Query: 237 RESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPR 296
           + ++T   V      ++   D  +G   P      P      +G   + +    GNP P 
Sbjct: 272 KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 331

Query: 297 VTWFK-NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           +TW K NG   I S         +   L + N Q  D+G Y   AEN  G     G L V
Sbjct: 332 ITWMKVNG--YIPSKAR---LRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 386



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 39/188 (20%), Positives = 64/188 (34%), Gaps = 6/188 (3%)

Query: 3041 DDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV 3100
            D+     P F     DI+  ++        +    G+      W  NG  I+     R  
Sbjct: 92   DESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYS 151

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
               G  ++    ++  DSG Y C ATN  G    S+              F+   ++   
Sbjct: 152  LIDGTFIISN-PSEAKDSGHYQCLATNTVG----SILSREATLQFAYLGNFSGRTRSAVS 206

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            +++GQ     C+  P   P++   W  N  P   +   +         L I+  Q  D G
Sbjct: 207  VREGQGVVLMCS-PPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVG 265

Query: 3221 EYVCRAYN 3228
             Y+C   N
Sbjct: 266  SYICLVKN 273



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 7/87 (8%)

Query: 1177 PVFVQPLSNP--PPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFG 1233
            PVFVQ   +   P  S+ K + L C  E  G+P     W  NG  + + S ++ +  D  
Sbjct: 99   PVFVQEPDDIIFPTDSDEKKVALNC--EVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT 156

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGS 1260
            F+  +   + + D+G Y   A N +GS
Sbjct: 157  FIISN--PSEAKDSGHYQCLATNTVGS 181



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL- 4680
            P +II P      ++ + +  +C++ G P+P+ +W +    I     ++ S     + + 
Sbjct: 105  PDDIIFPTD----SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIIS 160

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRV 4704
              SEA  +D G Y+C+A N+ G +
Sbjct: 161  NPSEA--KDSGHYQCLATNTVGSI 182



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            +G T   +C    +G+P   + W +    I   +R+ K+       + I +V+ +D G+Y
Sbjct: 314  KGTTVKMEC--FALGNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIY 367

Query: 2450 MCRASNLLGE 2459
             CRA N  G+
Sbjct: 368  ECRAENSRGK 377



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 5/87 (5%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V + Q V  ECK  P       + W K  + V    R   + D    +L I++    D G
Sbjct: 493  VTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 547

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
             Y CR  N+ G+ E+   L+ +  T I
Sbjct: 548  KYVCRGENVFGSAEIIASLSVKEPTRI 574



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 32/100 (32%), Positives = 42/100 (42%), Gaps = 10/100 (10%)

Query: 3817 SDAPKEEPIVSTPPKFITQ---IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL-- 3871
            SDA K++  V   P F+ +   I   T  + + V   C V     P  R  W RNG    
Sbjct: 86   SDAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYR--WLRNGTEID 143

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            L S +RY  +     +S       A+DSG Y C A N  G
Sbjct: 144  LESDYRYSLIDGTFIISNPS---EAKDSGHYQCLATNTVG 180



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 4111 PVFVSLPDAV---TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGMYH 4166
            PVFV  PD +   T  + +     C V G+P P   WL NG  I   S Y+ +  DG + 
Sbjct: 99   PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158

Query: 4167 FDIPKTRQYDTGKIEVI 4183
               P   + D+G  + +
Sbjct: 159  ISNPSEAK-DSGHYQCL 174



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)

Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
           ++ GNP P   W +NG  +   + +   +  + T +    ++  DSGHY  LA N  G I
Sbjct: 124 EVRGNPVPSYRWLRNGTEIDLESDYRY-SLIDGTFIISNPSEAKDSGHYQCLATNTVGSI 182

Query: 348 VT 349
           ++
Sbjct: 183 LS 184



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 2518 SELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAND 2577
            ++L  G    +E +    G P   + W  NGV L   SR    +      L I++V  +D
Sbjct: 399  TQLDSGSPLRWECKAT--GKPRPTYRWLKNGVPLSPQSRVEMVNG----VLMIHNVNQSD 452

Query: 2578 AGLYMCKAINRAG 2590
            AG+Y C A N+ G
Sbjct: 453  AGMYQCLAENKYG 465



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 1/94 (1%)

Query: 2635 DTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKST 2694
            D  V   P+F           +     +    E R +P     W +NG  +   +  + +
Sbjct: 92   DESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYS 151

Query: 2695 FDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
               G   +S N     DSG Y C ATN +G  +S
Sbjct: 152  LIDGTFIIS-NPSEAKDSGHYQCLATNTVGSILS 184



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 6/97 (6%)

Query: 2641 APIFTTH-LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            AP F  + LK    + + Q V +E +  P+  P   I W K    +    R+    D  L
Sbjct: 479  APTFALNQLKKTIIVTKDQEVVIECK--PQGSPKPTISWKKGDRAVRENKRIAILPDGSL 536

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              L+ +     D G Y C+  N+ G A   AS+ +++
Sbjct: 537  RILNASK---SDEGKYVCRGENVFGSAEIIASLSVKE 570


>AL163282-1|CAB90436.1|  812|Homo sapiens human CHD2-52 down syndrome
            cell adhesion molecule protein.
          Length = 812

 Score =  112 bits (269), Expect = 3e-23
 Identities = 97/383 (25%), Positives = 160/383 (41%), Gaps = 43/383 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P  +W ++N P++ S  FQ     T + L+I  +   DS  +     NR GTAK  
Sbjct: 80   GHPEPDYRWLKDNMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVI 135

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              L V++          P   T++ + V  + G  V L   VTGT+  ++ W +NG+ + 
Sbjct: 136  GRLYVKQ----------PLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILN 185

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P  +N  +       L++      D G Y+C        A+   + V+            
Sbjct: 186  PG-KNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLE----------- 233

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKY--FQMS 4672
                +  P+II    +K+V+  + +   C + G PLPT+ W    D ++K   +   QM 
Sbjct: 234  ----DGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMI 289

Query: 4673 RTADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
             +       L IS +   D G Y+C A NSAG V   A++ V  P       ++ P+++I
Sbjct: 290  TSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGP------ASIRPMKNI 343

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                G+      ++      +I+W +   L+P     Q+  E N  + L     E D G 
Sbjct: 344  TAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGE 402

Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813
            +TC       Q+ TS  + V  K
Sbjct: 403  YTCNVLVQP-QLSTSQSVHVTVK 424



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 94/382 (24%), Positives = 145/382 (37%), Gaps = 34/382 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G PLP I W  ++ PI      +I    T    ++  + +  S V        GG  +C+
Sbjct: 262  GTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQV------RDGGVYRCT 315

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            AN        Q R  +  P+     +N+   +G+   +  +V G     + W KN   + 
Sbjct: 316  ANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLP 375

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
             + R    E +GT  L  ++    D G+Y C  +            V    +T       
Sbjct: 376  FNHRQVAFENNGTLKLSDVQK-EVDEGEYTCNVL------------VQPQLSTSQSVHVT 422

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRT 4674
             K     P  I+P +    + GQ +   C +V   LP T+ W K  + I  S    +   
Sbjct: 423  VKV----PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI 478

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +LRIS       G+Y C+A N A  V   ++L V  P +    P     RD     
Sbjct: 479  DFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP-----RDQDGIY 533

Query: 4735 GQPAQFKTQITSKIKPTIQW-LREGALIPETPDFQM---IHEGNNAVLLIGNTYEEDTGT 4790
            G+             PTI W   +GA +P+     +   I   +N  LLI +  EED+G 
Sbjct: 534  GKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGY 593

Query: 4791 FTCRATTAAG-QVETSAKLVVK 4811
            + C+ +   G  V  S  L VK
Sbjct: 594  YLCKVSNDVGADVSKSMYLTVK 615



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 79/336 (23%), Positives = 133/336 (39%), Gaps = 49/336 (14%)

Query: 235 SFRESITKRYVGESDVQIST-EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293
           + R S +  YV E   +  T ++   L    P K    PR  K   G+       ++G  
Sbjct: 112 NIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTE 171

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
              ++W++NG+ ++N  K+  IT  NH  L + +  KSD G Y         C V    L
Sbjct: 172 DQELSWYRNGE-ILNPGKNVRITGINHENLIMDHMVKSDGGAYQ--------CFVRKDKL 222

Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
           + +   +  ++D   + I+             SEK ++P              +     C
Sbjct: 223 SAQDYVQVVLEDGTPKIIS-----------AFSEKVVSP-------------AEPVSLMC 258

Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKI--LVNESGN--HALMITNVTLSDSGVVTCVARN 469
            V G P P +TW ++D  I    +H+I  ++   GN    L I++  + D GV  C A N
Sbjct: 259 NVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANN 318

Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
            +G   +Q R+N      V  P  +     +    G    ++ R +G P   I W K+  
Sbjct: 319 SAGVVLYQARIN------VRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNS- 371

Query: 530 PIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            ++P  + ++    +G     D+   K  D   Y C
Sbjct: 372 NLLPFNHRQVAFENNGTLKLSDV--QKEVDEGEYTC 405



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 55/178 (30%), Positives = 78/178 (43%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C VTG    E++W+ N   +    N +I      N  L++ ++  SD G   C
Sbjct: 158 GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQC 215

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
             R    + + Q  + V+ ++    PK +  FS   V   EPV L     GTP P ITW 
Sbjct: 216 FVRKD--KLSAQDYVQVVLEDGT--PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWT 271

Query: 526 KDGVPIIPNPELRIH---TDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+     RI    T  G   S L+I  ++  D   Y+CTA N AG    +AR+
Sbjct: 272 LDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 329



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 68/285 (23%), Positives = 115/285 (40%), Gaps = 31/285 (10%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V+G  PI + W K+G+ +   +   I   D T +L I       +G Y C+A N A    
Sbjct: 450  VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 509

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
              ++ +V +P               P  +++P +D+    G+A+  +C   G P+PT+ W
Sbjct: 510  HQSQLIVRVP---------------PKFVVQP-RDQDGIYGKAVILNCSAEGYPVPTIVW 553

Query: 4657 Y----KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLK 4711
                  G    +P       +     +L I     ED G Y C   N  G  V+ +  L 
Sbjct: 554  KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 613

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDF--- 4767
            V  P    + P  T     +  +GQ  +       +    ++W +E  +I PE   +   
Sbjct: 614  VKIPAMITSYPNTT-----LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 668

Query: 4768 -QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             + + E   + L I  T  ED+G F+C A  + G+     +L V+
Sbjct: 669  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 713



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 46/175 (26%), Positives = 72/175 (41%), Gaps = 10/175 (5%)

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
            AN+ P I++    +    GQ +E  CK +G P P  +W K +  ++ S  FQ + T    
Sbjct: 51   ANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG--- 107

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
             L I    P D G Y C   N  G   V  +L V QP +A   P     R +    G   
Sbjct: 108  -LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISP-----RKVKSSVGSQV 161

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                 +T      + W R G ++    + + I   N+  L++ +  + D G + C
Sbjct: 162  SLSCSVTGTEDQELSWYRNGEILNPGKNVR-ITGINHENLIMDHMVKSDGGAYQC 215



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 70/290 (24%), Positives = 114/290 (39%), Gaps = 30/290 (10%)

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
            +GQ V L  K  G    D  WLK+   ++   R    ++  T  LLI    P DSG Y C
Sbjct: 68   AGQRVELPCKALGHPEPDYRWLKDNMPLELSGR---FQKTVT-GLLIENIRPSDSGSYVC 123

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
               N  G A+      V  P          KA  +P ++    K  +   G  +  SC +
Sbjct: 124  EVSNRYGTAKVIGRLYVKQP---------LKATISPRKV----KSSV---GSQVSLSCSV 167

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G     + WY+  +++ P K  +++    E  L +      D G Y+C  +    +++ 
Sbjct: 168  TGTEDQELSWYRNGEILNPGKNVRITGINHE-NLIMDHMVKSDGGAYQC--FVRKDKLSA 224

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               ++V   D    +  ++   + VV   +P      +     PTI W  +   I +   
Sbjct: 225  QDYVQVVLEDGTPKI--ISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGS 282

Query: 4767 F---QMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                QMI    N V  L I ++   D G + C A  +AG V   A++ V+
Sbjct: 283  HRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR 332



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 73/287 (25%), Positives = 111/287 (38%), Gaps = 35/287 (12%)

Query: 4439 LPL-IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            LP+ I W ++  PI  S    I      S L I  + +  +  +  +A N     +  + 
Sbjct: 454  LPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQ 513

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKV-- 4554
            L+V           VPP F +  ++ +   G+ V L+    G     + W    G  V  
Sbjct: 514  LIVR----------VPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQ 563

Query: 4555 -QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
             QP   N  ++     +LLI     +DSG Y C   N  G     A+   S+  T   P 
Sbjct: 564  FQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG-----ADVSKSMYLTVKIPA 618

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP--SKYFQM 4671
              T   N            +  +GQ  E SC   G+    V+W K D++I P  ++Y   
Sbjct: 619  MITSYPNTT----------LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 668

Query: 4672 SRTADE---YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            ++   E    TL+I     ED G + C A NS G      +L V +P
Sbjct: 669  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP 715



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 19/209 (9%)

Query: 376 QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRD 434
           Q  T + + ++ K   P F++  +    + G+     C V     P  +TW  + R I  
Sbjct: 412 QLSTSQSVHVTVKV--PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPG 469

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
                I  N     +L I+N++L  +G  TC+ARN++     Q +L V      V PKFV
Sbjct: 470 SLGVTI-DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIV-----RVPPKFV 523

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKD---GV----PIIPNPELRIHTDGGAST 547
            +    +   G+ V+LN  A G P P I W+     GV    PI  N  +++ ++G   +
Sbjct: 524 VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG---S 580

Query: 548 LDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           L I      D+ +Y C   N  G+  +++
Sbjct: 581 LLIKHVVEEDSGYYLCKVSNDVGADVSKS 609



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 50/191 (26%), Positives = 80/191 (41%), Gaps = 14/191 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T   CRV G PY  + W+ N   +   +NH+ +  E+ N  L 
Sbjct: 334 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFEN-NGTLK 390

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +++V    D G  TC           Q +L+  +   V    P F++ F       G+ V
Sbjct: 391 LSDVQKEVDEGEYTC-------NVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRV 443

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +    V    P  ITWQKDG PI  +  + I      S+L I          Y C A+N
Sbjct: 444 FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARN 503

Query: 568 VAGSTATRARL 578
            A +   +++L
Sbjct: 504 EAAAVEHQSQL 514



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 50/199 (25%), Positives = 87/199 (43%), Gaps = 15/199 (7%)

Query: 367 RSQYITDTQQRETEERIEISEKA-LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           R +Y  +T+Q  +  R+ +S+ A  AP  +     R    G+     C+  G P P+  W
Sbjct: 30  RHRYTGETRQSNSA-RLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRW 88

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             ++  +  + + +     +G   L+I N+  SDSG   C   N+ G      RL V + 
Sbjct: 89  LKDNMPL--ELSGRFQKTVTG---LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 143

Query: 486 -EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            +  ++P+ V+  S++    G  V L+    GT    ++W ++G  + P   +RI T   
Sbjct: 144 LKATISPRKVK--SSV----GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI-TGIN 196

Query: 545 ASTLDIPRAKASDAAWYQC 563
              L +     SD   YQC
Sbjct: 197 HENLIMDHMVKSDGGAYQC 215



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 68/252 (26%), Positives = 95/252 (37%), Gaps = 35/252 (13%)

Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
            I   E   +EH++Q   RV         PP F  + +       +        +G P+P 
Sbjct: 500  IARNEAAAVEHQSQLIVRV---------PPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT 550

Query: 4442 IKWYRENFPIKNSPDFQ-------IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            I W          P FQ       I   S  S+LI + V  EDS  +     N  G A  
Sbjct: 551  IVWKFSKGA--GVPQFQPIALNGRIQVLSNGSLLI-KHVVEEDSGYYLCKVSNDVG-ADV 606

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            S ++ +  K        +P   T        T GQ   +     G KPI V W K  + +
Sbjct: 607  SKSMYLTVK--------IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRII 658

Query: 4555 QPD-----IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             P+     +  K + E+   TL IL    +DSG + C AINS GE R   +  V  P   
Sbjct: 659  NPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP--P 716

Query: 4610 DKPKPQTKAANA 4621
            D P+ + K   A
Sbjct: 717  DPPEIEIKDVKA 728



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 64/322 (19%), Positives = 110/322 (34%), Gaps = 24/322 (7%)

Query: 45  TRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVS 104
           TR   T      +   +    P   +P I +  F + +   G   +   K  G+P P   
Sbjct: 29  TRHRYTGETRQSNSARLFVSDPANSAPSILDG-FDHRKAMAGQRVELPCKALGHPEPDYR 87

Query: 105 WTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
           W +   PL    + S R+ +      LLI+ I P D G Y C   N+YG A      +  
Sbjct: 88  WLKDNMPL----ELSGRFQKTV--TGLLIENIRPSDSGSYVCEVSNRYGTA------KVI 135

Query: 165 GXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVD 224
           G              R V  +V  +   +   T  + ++     Y NG   +   + ++ 
Sbjct: 136 GRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS--WYRNGEILNPGKNVRIT 193

Query: 225 TFEYRLL---REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGA 281
              +  L     V       + +V +  +     +   L   +P KI        +    
Sbjct: 194 GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP-KIISAFSEKVVSPAE 252

Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI---ITTHNHTT--LRVRNTQKSDSGHY 336
                  + G P P +TW  +   ++    H I   IT+  +    L + ++Q  D G Y
Sbjct: 253 PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVY 312

Query: 337 TLLAENPNGCIVTSGYLAVESP 358
              A N  G ++    + V  P
Sbjct: 313 RCTANNSAGVVLYQARINVRGP 334



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 4/93 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P+K++TA+ G   +   R+  +G P   I+W KN   +  + R  +    G + L
Sbjct: 334 PASIRPMKNITAIAGRDTYIHCRV--IGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 391

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             +   + D GEYTC  +    ++ +++V HVT
Sbjct: 392 SDVQKEV-DEGEYTCNVLVQPQLSTSQSV-HVT 422



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 11/145 (7%)

Query: 439 KILVNESGNHALMITNVTLSDSGV-VTCVARNK-SGET--AFQCRLNVIEKEQVVAPKFV 494
           + L+  +G  AL I +V   D      C+ R++ +GET  +   RL V +     AP  +
Sbjct: 2   RFLITSTG--ALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANS-APSIL 58

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
           + F       G+ V L  +A+G P P   W KD +P+    EL        + L I   +
Sbjct: 59  DGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPL----ELSGRFQKTVTGLLIENIR 114

Query: 555 ASDAAWYQCTAQNVAGSTATRARLY 579
            SD+  Y C   N  G+     RLY
Sbjct: 115 PSDSGSYVCEVSNRYGTAKVIGRLY 139



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/108 (30%), Positives = 47/108 (43%), Gaps = 6/108 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW-YRNGKLLPSGHRYRT--- 3880
            IV  PPKF+ Q +       + V   C  E    P   I W +  G  +P          
Sbjct: 515  IVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT--IVWKFSKGAGVPQFQPIALNGR 572

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +  +   SL I +V  EDSG Y+C+  ND G D +K+     K+P +I
Sbjct: 573  IQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMI 620



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 63/281 (22%), Positives = 105/281 (37%), Gaps = 26/281 (9%)

Query: 95  LRGNPTPVVSWTRKKAPLVE--CNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQ 151
           ++G P P ++WT    P+++   ++ S     +   VS L I      D G Y CTA N 
Sbjct: 260 VKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 319

Query: 152 YGEAICSVYIQPEGXXXXX-----XXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR--QT 204
            G  +    I   G                  Y H    + +  Y  + Y          
Sbjct: 320 AGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHC-RVIGYPYYSIKWYKNSNLLPFNH 378

Query: 205 QKVAY-TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
           ++VA+  NGT   S    +VD  EY     V  + S ++       V ++ ++   + P 
Sbjct: 379 RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQ------SVHVTVKVPPFIQPF 432

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
             P+ +   R             V +SG+    +TW K+G+ +  S    I      ++L
Sbjct: 433 EFPRFSIGQRVFIPC--------VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSL 484

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           R+ N     +G+YT +A N    +     L V  P +  VQ
Sbjct: 485 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQ 525



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 8/120 (6%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV--- 3173
            DSG Y C+ +N  G A++S  +    K     P   T   N      GQ     CT    
Sbjct: 590  DSGYYLCKVSNDVG-ADVSKSMYLTVKI----PAMITSYPNTTLATQGQKKEMSCTAHGE 644

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+     K +   N +  R+    K V +     L I  T   DSG + C A N YGED
Sbjct: 645  KPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGED 704



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 4/125 (3%)

Query: 243 RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
           RY GE+    S  +  S    S P I     + K   G   +   +  G+P P   W K+
Sbjct: 32  RYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKD 91

Query: 303 GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
              L  S + +   T     L + N + SDSG Y     N  G     G L V+ P ++ 
Sbjct: 92  NMPLELSGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKAT 147

Query: 363 VQDQR 367
           +  ++
Sbjct: 148 ISPRK 152



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            +G P+    WL++ +P+E S R           L ++ + P DSG+Y C   N  G A  
Sbjct: 79   LGHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTAKV 134

Query: 1797 SSTLFVQ 1803
               L+V+
Sbjct: 135  IGRLYVK 141



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/141 (21%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W  +   +E S R +     G+++  I   + +DSG+Y C  +N++G A++  +L     
Sbjct: 88   WLKDNMPLELSGRFQKTVT-GLLIENI---RPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 143

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             K      T   + ++    G      C+V   +  D ++ WY NG+ +     ++ ++ 
Sbjct: 144  LKA-----TISPRKVKS-SVGSQVSLSCSVTGTE--DQELSWYRNGEILNPGKNVR-ITG 194

Query: 3204 FGFVVLDIAYTQNHDSGEYVC 3224
                 L + +    D G Y C
Sbjct: 195  INHENLIMDHMVKSDGGAYQC 215



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 43/190 (22%), Positives = 73/190 (38%), Gaps = 18/190 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL---VNESGNH 448
           P+FV   +D+D   GK    +C   G P P + W  +       +    L   +    N 
Sbjct: 520 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG 579

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEP 507
           +L+I +V   DSG   C   N  G    +     ++      P  +  + +T    +G+ 
Sbjct: 580 SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVK-----IPAMITSYPNTTLATQGQK 634

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT-------DGGASTLDIPRAKASDAAW 560
             ++  A G     + W+K+    I NPE+  +        +   STL I      D+ +
Sbjct: 635 KEMSCTAHGEKPIIVRWEKE--DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 692

Query: 561 YQCTAQNVAG 570
           + C A N  G
Sbjct: 693 FSCHAINSYG 702



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYV-ALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            GD  + + W KDGRP+  S  + T  N  +  +L I ++++   G+YTC A N       
Sbjct: 452  GDLPITITWQKDGRPIPGSLGV-TIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEH 510

Query: 996  SANLTIVTKKDIIAESQHPGGL 1017
             + L +      + + +   G+
Sbjct: 511  QSQLIVRVPPKFVVQPRDQDGI 532



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   +P++NI  I  G+  +  CR+I  G P   ++W++N  L+  + R     + G  +
Sbjct: 334  PASIRPMKNITAIA-GRDTYIHCRVI--GYPYYSIKWYKNSNLLPFNHRQVAFENNG--T 388

Query: 2436 MTISHVRDE-DEGVYMC 2451
            + +S V+ E DEG Y C
Sbjct: 389  LKLSDVQKEVDEGEYTC 405



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 7/104 (6%)

Query: 2623 EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG 2682
            E   +    +FV      AP        + K + GQ V L  +     +P+ +  W K+ 
Sbjct: 36   ETRQSNSARLFVSDPANSAPSILDGF-DHRKAMAGQRVELPCKALGHPEPDYR--WLKDN 92

Query: 2683 VTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            + L    R + T    +  L I ++R  DSG Y C+ +N  G A
Sbjct: 93   MPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTA 132



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  I  +K+ T          CRV     P   I+WY+N  LLP  HR     + G + L
Sbjct: 334  PASIRPMKNITAIAGRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 391

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              +     D GEY C  +       +++     K+P  I   + PR
Sbjct: 392  SDVQKEV-DEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR 436



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSG 3875
            +D  K   +    P  IT   + T+  ++G + E       +  + + W +  +++ P  
Sbjct: 604  ADVSKSMYLTVKIPAMITSYPNTTLA-TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEM 662

Query: 3876 HRY----RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             RY    + V +    +L IL    EDSG + C A+N +GED     ++ ++ PD
Sbjct: 663  ARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD 717



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 13/134 (9%)

Query: 3094 SHRI-RTVYAFGMVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPR 3150
            SHRI + + + G VV  L I  ++  D G Y C A N  G      ++        + P 
Sbjct: 282  SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV------RGPA 335

Query: 3151 FTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLD 3210
                ++NI  +  G+  +  C V+    P   I+WY N   +  + R     + G + L 
Sbjct: 336  SIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKLS 392

Query: 3211 IAYTQNHDSGEYVC 3224
                +  D GEY C
Sbjct: 393  -DVQKEVDEGEYTC 405



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 32/130 (24%), Positives = 48/130 (36%), Gaps = 13/130 (10%)

Query: 1543 VRSTQNEAGLEQIQVL-------EDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRA 1595
            ++  QNE GL   + +       E R        V +    AP       + +   GQR 
Sbjct: 13   IKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRV 72

Query: 1596 HFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAI 1655
                + +   +   +  W  +N PL+   RF +T       L I +  P DSG+Y C   
Sbjct: 73   ELPCKALGHPEPDYR--WLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVS 126

Query: 1656 NALGEAVTSG 1665
            N  G A   G
Sbjct: 127  NRYGTAKVIG 136



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 7/100 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKS----THDFSYVS 2832
            IS  +  V    + +   CNV+ +  PT  I W  ++ P+  G  ++     T + + VS
Sbjct: 240  ISAFSEKVVSPAEPVSLMCNVKGTPLPT--ITWTLDDDPILKGGSHRISQMITSEGNVVS 297

Query: 2833 -LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
             L+I+ +   D G+Y C A NS G       +   G  +I
Sbjct: 298  YLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI 337



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 7/99 (7%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH-RYRTSN-DFG- 1900
            P  IT     T  ++GQ     C    + +  + V W    +++     RY  S  + G 
Sbjct: 617  PAMITSYPNTTLATQGQKKEMSCTA--HGEKPIIVRWEKEDRIINPEMARYLVSTKEVGE 674

Query: 1901 --FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               + L IL    EDSG ++C AIN+ G+    I+L VQ
Sbjct: 675  EVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 713



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + P  I  +   T ++ G+  +  CR+  YP     ++WY N  +L   HR     + G 
Sbjct: 332  RGPASIRPMKNITAIA-GRDTYIHCRVIGYP--YYSIKWYKNSNLLPFNHRQVAFENNG- 387

Query: 1902 AALDILTVYGE-DSGEYTCKAI 1922
              L +  V  E D GEYTC  +
Sbjct: 388  -TLKLSDVQKEVDEGEYTCNVL 408



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 6/68 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            GQ     C+ +  G P     W ++   +E S R  KT       + I ++R  D G Y+
Sbjct: 69   GQRVELPCKAL--GHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYV 122

Query: 2451 CRASNLLG 2458
            C  SN  G
Sbjct: 123  CEVSNRYG 130



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI-KTVSDFGFVVLDIAYTQNHDSGEY 3222
            GQ     C  +   +PD +  W  +  P+  S R  KTV+  G ++ +I   +  DSG Y
Sbjct: 69   GQRVELPCKALGHPEPDYR--WLKDNMPLELSGRFQKTVT--GLLIENI---RPSDSGSY 121

Query: 3223 VCRAYNKYG 3231
            VC   N+YG
Sbjct: 122  VCEVSNRYG 130



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 9/94 (9%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG-----QPVTIGHRFR 1494
            V + P+FV +P+  ++ I G+ V   C  E      +  ++ K       QP+ +  R +
Sbjct: 516  VRVPPKFVVQPRD-QDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQ 574

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             + +   +   +++   EDSG Y C+  N VG D
Sbjct: 575  VLSNGSLLIKHVVE---EDSGYYLCKVSNDVGAD 605



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKD  P+E S R    F      L I+++   D+G Y C   N  G A     L +
Sbjct: 88   WLKDNMPLELSGR----FQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 140



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 1/98 (1%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V  + P F  P +  R +  Q   F   ++  GD  + + W ++G PI  S  +T  +  
Sbjct: 421  VTVKVPPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNID 479

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
               +L +  ++   +G YTC A NE       S L V+
Sbjct: 480  FTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR 517



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP       + + + G  V L C+   +G       W  +  P++   RF+         
Sbjct: 54   APSILDGFDHRKAMAGQRVELPCKA--LGHPEPDYRWLKDNMPLELSGRFQKTV----TG 107

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEA 1394
            L + ++ P DSG Y C+ +N+ G A
Sbjct: 108  LLIENIRPSDSGSYVCEVSNRYGTA 132



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 35/171 (20%), Positives = 70/171 (40%), Gaps = 14/171 (8%)

Query: 3072 LIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            ++ +GD  + I W  +G+ I  S  +          L I       +G Y+C A N+   
Sbjct: 448  VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 507

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-- 3189
             E   +L          P+F    ++ +G+  G++    C+      P +  ++      
Sbjct: 508  VEHQSQLIV-----RVPPKFVVQPRDQDGIY-GKAVILNCSAEGYPVPTIVWKFSKGAGV 561

Query: 3190 ---QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
               QP+  + RI+ +S+   ++  +      DSG Y+C+  N  G D +++
Sbjct: 562  PQFQPIALNGRIQVLSNGSLLIKHVV---EEDSGYYLCKVSNDVGADVSKS 609



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P  I  ++++T +  G+  +   R++    P   ++W+ N   LP  HR   F + G + 
Sbjct: 334  PASIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLK 390

Query: 3342 LDILYCYEENSGEYEC 3357
            L  +   E + GEY C
Sbjct: 391  LSDVQ-KEVDEGEYTC 405



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
           T + P FI+P +       G+       +    D  + + W KDGRPI  S  +T I N 
Sbjct: 422 TVKVPPFIQPFE-FPRFSIGQRVFIPCVVVS-GDLPITITWQKDGRPIPGSLGVT-IDNI 478

Query: 826 GYV-SLNIMHLRAEDAGSYTVRAVNK 850
            +  SL I +L     G+YT  A N+
Sbjct: 479 DFTSSLRISNLSLMHNGNYTCIARNE 504



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 5/106 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS- 695
           P FI P +      G ++ F   +   GD  + I W K+G+ I  S   T I    + S 
Sbjct: 426 PPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVT-IDNIDFTSS 483

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAE--TKAVLHVTPRATIERTSQ 739
           L + +L++  +G YTC A +     E  ++ ++ V P+  ++   Q
Sbjct: 484 LRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQ 529



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 13/92 (14%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW-FHNG------RPFATGSRVHT 3746
            PP+F V+ +D  D   G  V  +C  E  G P   I W F  G      +P A   R+  
Sbjct: 519  PPKFVVQPRDQ-DGIYGKAVILNCSAE--GYPVPTIVWKFSKGAGVPQFQPIALNGRIQV 575

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            L++   +   I ++   D+G Y C+ +N  G+
Sbjct: 576  LSNGSLL---IKHVVEEDSGYYLCKVSNDVGA 604


>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhesion
            molecule splice variant protein.
          Length = 1746

 Score =  112 bits (269), Expect = 3e-23
 Identities = 97/383 (25%), Positives = 160/383 (41%), Gaps = 43/383 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P  +W ++N P++ S  FQ     T + L+I  +   DS  +     NR GTAK  
Sbjct: 2    GHPEPDYRWLKDNMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVI 57

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              L V++          P   T++ + V  + G  V L   VTGT+  ++ W +NG+ + 
Sbjct: 58   GRLYVKQ----------PLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILN 107

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P  +N  +       L++      D G Y+C        A+   + V+            
Sbjct: 108  PG-KNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLE----------- 155

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKY--FQMS 4672
                +  P+II    +K+V+  + +   C + G PLPT+ W    D ++K   +   QM 
Sbjct: 156  ----DGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMI 211

Query: 4673 RTADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
             +       L IS +   D G Y+C A NSAG V   A++ V  P       ++ P+++I
Sbjct: 212  TSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGP------ASIRPMKNI 265

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                G+      ++      +I+W +   L+P     Q+  E N  + L     E D G 
Sbjct: 266  TAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGE 324

Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813
            +TC       Q+ TS  + V  K
Sbjct: 325  YTCNVLVQP-QLSTSQSVHVTVK 346



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 94/382 (24%), Positives = 145/382 (37%), Gaps = 34/382 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G PLP I W  ++ PI      +I    T    ++  + +  S V        GG  +C+
Sbjct: 184  GTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQV------RDGGVYRCT 237

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            AN        Q R  +  P+     +N+   +G+   +  +V G     + W KN   + 
Sbjct: 238  ANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLP 297

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
             + R    E +GT  L  ++    D G+Y C  +            V    +T       
Sbjct: 298  FNHRQVAFENNGTLKLSDVQK-EVDEGEYTCNVL------------VQPQLSTSQSVHVT 344

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRT 4674
             K     P  I+P +    + GQ +   C +V   LP T+ W K  + I  S    +   
Sbjct: 345  VKV----PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI 400

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +LRIS       G+Y C+A N A  V   ++L V  P +    P     RD     
Sbjct: 401  DFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP-----RDQDGIY 455

Query: 4735 GQPAQFKTQITSKIKPTIQW-LREGALIPETPDFQM---IHEGNNAVLLIGNTYEEDTGT 4790
            G+             PTI W   +GA +P+     +   I   +N  LLI +  EED+G 
Sbjct: 456  GKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGY 515

Query: 4791 FTCRATTAAG-QVETSAKLVVK 4811
            + C+ +   G  V  S  L VK
Sbjct: 516  YLCKVSNDVGADVSKSMYLTVK 537



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 79/336 (23%), Positives = 133/336 (39%), Gaps = 49/336 (14%)

Query: 235 SFRESITKRYVGESDVQIST-EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293
           + R S +  YV E   +  T ++   L    P K    PR  K   G+       ++G  
Sbjct: 34  NIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTE 93

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
              ++W++NG+ ++N  K+  IT  NH  L + +  KSD G Y         C V    L
Sbjct: 94  DQELSWYRNGE-ILNPGKNVRITGINHENLIMDHMVKSDGGAYQ--------CFVRKDKL 144

Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
           + +   +  ++D   + I+             SEK ++P              +     C
Sbjct: 145 SAQDYVQVVLEDGTPKIIS-----------AFSEKVVSP-------------AEPVSLMC 180

Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKI--LVNESGN--HALMITNVTLSDSGVVTCVARN 469
            V G P P +TW ++D  I    +H+I  ++   GN    L I++  + D GV  C A N
Sbjct: 181 NVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANN 240

Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
            +G   +Q R+N      V  P  +     +    G    ++ R +G P   I W K+  
Sbjct: 241 SAGVVLYQARIN------VRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNS- 293

Query: 530 PIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            ++P  + ++    +G     D+   K  D   Y C
Sbjct: 294 NLLPFNHRQVAFENNGTLKLSDV--QKEVDEGEYTC 327



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 55/178 (30%), Positives = 78/178 (43%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C VTG    E++W+ N   +    N +I      N  L++ ++  SD G   C
Sbjct: 80  GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQC 137

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
             R    + + Q  + V+ ++    PK +  FS   V   EPV L     GTP P ITW 
Sbjct: 138 FVRKD--KLSAQDYVQVVLEDGT--PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWT 193

Query: 526 KDGVPIIPNPELRIH---TDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+     RI    T  G   S L+I  ++  D   Y+CTA N AG    +AR+
Sbjct: 194 LDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 251



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 68/285 (23%), Positives = 115/285 (40%), Gaps = 31/285 (10%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V+G  PI + W K+G+ +   +   I   D T +L I       +G Y C+A N A    
Sbjct: 372  VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 431

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
              ++ +V +P               P  +++P +D+    G+A+  +C   G P+PT+ W
Sbjct: 432  HQSQLIVRVP---------------PKFVVQP-RDQDGIYGKAVILNCSAEGYPVPTIVW 475

Query: 4657 Y----KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLK 4711
                  G    +P       +     +L I     ED G Y C   N  G  V+ +  L 
Sbjct: 476  KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 535

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDF--- 4767
            V  P    + P  T     +  +GQ  +       +    ++W +E  +I PE   +   
Sbjct: 536  VKIPAMITSYPNTT-----LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 590

Query: 4768 -QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             + + E   + L I  T  ED+G F+C A  + G+     +L V+
Sbjct: 591  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 635



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 73/287 (25%), Positives = 111/287 (38%), Gaps = 35/287 (12%)

Query: 4439 LPL-IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            LP+ I W ++  PI  S    I      S L I  + +  +  +  +A N     +  + 
Sbjct: 376  LPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQ 435

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKV-- 4554
            L+V           VPP F +  ++ +   G+ V L+    G     + W    G  V  
Sbjct: 436  LIVR----------VPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQ 485

Query: 4555 -QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
             QP   N  ++     +LLI     +DSG Y C   N  G     A+   S+  T   P 
Sbjct: 486  FQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG-----ADVSKSMYLTVKIPA 540

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP--SKYFQM 4671
              T   N            +  +GQ  E SC   G+    V+W K D++I P  ++Y   
Sbjct: 541  MITSYPNTT----------LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 590

Query: 4672 SRTADE---YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            ++   E    TL+I     ED G + C A NS G      +L V +P
Sbjct: 591  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP 637



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 19/209 (9%)

Query: 376 QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRD 434
           Q  T + + ++ K   P F++  +    + G+     C V     P  +TW  + R I  
Sbjct: 334 QLSTSQSVHVTVKV--PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPG 391

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
                I  N     +L I+N++L  +G  TC+ARN++     Q +L V      V PKFV
Sbjct: 392 SLGVTI-DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIV-----RVPPKFV 445

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKD---GV----PIIPNPELRIHTDGGAST 547
            +    +   G+ V+LN  A G P P I W+     GV    PI  N  +++ ++G   +
Sbjct: 446 VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG---S 502

Query: 548 LDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           L I      D+ +Y C   N  G+  +++
Sbjct: 503 LLIKHVVEEDSGYYLCKVSNDVGADVSKS 531



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 50/191 (26%), Positives = 80/191 (41%), Gaps = 14/191 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T   CRV G PY  + W+ N   +   +NH+ +  E+ N  L 
Sbjct: 256 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFEN-NGTLK 312

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +++V    D G  TC           Q +L+  +   V    P F++ F       G+ V
Sbjct: 313 LSDVQKEVDEGEYTC-------NVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRV 365

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +    V    P  ITWQKDG PI  +  + I      S+L I          Y C A+N
Sbjct: 366 FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARN 425

Query: 568 VAGSTATRARL 578
            A +   +++L
Sbjct: 426 EAAAVEHQSQL 436



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 68/252 (26%), Positives = 95/252 (37%), Gaps = 35/252 (13%)

Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
            I   E   +EH++Q   RV         PP F  + +       +        +G P+P 
Sbjct: 422  IARNEAAAVEHQSQLIVRV---------PPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT 472

Query: 4442 IKWYRENFPIKNSPDFQ-------IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            I W          P FQ       I   S  S+LI + V  EDS  +     N  G A  
Sbjct: 473  IVWKFSKGA--GVPQFQPIALNGRIQVLSNGSLLI-KHVVEEDSGYYLCKVSNDVG-ADV 528

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            S ++ +  K        +P   T        T GQ   +     G KPI V W K  + +
Sbjct: 529  SKSMYLTVK--------IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRII 580

Query: 4555 QPD-----IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             P+     +  K + E+   TL IL    +DSG + C AINS GE R   +  V  P   
Sbjct: 581  NPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP--P 638

Query: 4610 DKPKPQTKAANA 4621
            D P+ + K   A
Sbjct: 639  DPPEIEIKDVKA 650



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 37/147 (25%), Positives = 58/147 (39%), Gaps = 10/147 (6%)

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            +G P P  +W K +  ++ S  FQ + T     L I    P D G Y C   N  G   V
Sbjct: 1    LGHPEPDYRWLKDNMPLELSGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKV 56

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
              +L V QP +A   P     R +    G        +T      + W R G ++    +
Sbjct: 57   IGRLYVKQPLKATISP-----RKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKN 111

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
             + I   N+  L++ +  + D G + C
Sbjct: 112  VR-ITGINHENLIMDHMVKSDGGAYQC 137



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 4/93 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P+K++TA+ G   +   R+  +G P   I+W KN   +  + R  +    G + L
Sbjct: 256 PASIRPMKNITAIAGRDTYIHCRV--IGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 313

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             +   + D GEYTC  +    ++ +++V HVT
Sbjct: 314 SDVQKEV-DEGEYTCNVLVQPQLSTSQSV-HVT 344



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 55/270 (20%), Positives = 94/270 (34%), Gaps = 23/270 (8%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G+P P   W +   PL    + S R+ +      LLI+ I P D G Y C   N+YG A 
Sbjct: 2   GHPEPDYRWLKDNMPL----ELSGRFQKTV--TGLLIENIRPSDSGSYVCEVSNRYGTA- 54

Query: 157 CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
                +  G              R V  +V  +   +   T  + ++     Y NG   +
Sbjct: 55  -----KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS--WYRNGEILN 107

Query: 217 STDDFKVDTFEYRLL---REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
              + ++    +  L     V       + +V +  +     +   L   +P KI     
Sbjct: 108 PGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP-KIISAFS 166

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI---ITTHNHTT--LRVRNT 328
              +           + G P P +TW  +   ++    H I   IT+  +    L + ++
Sbjct: 167 EKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSS 226

Query: 329 QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           Q  D G Y   A N  G ++    + V  P
Sbjct: 227 QVRDGGVYRCTANNSAGVVLYQARINVRGP 256



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/108 (30%), Positives = 47/108 (43%), Gaps = 6/108 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW-YRNGKLLPSGHRYRT--- 3880
            IV  PPKF+ Q +       + V   C  E    P   I W +  G  +P          
Sbjct: 437  IVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT--IVWKFSKGAGVPQFQPIALNGR 494

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +  +   SL I +V  EDSG Y+C+  ND G D +K+     K+P +I
Sbjct: 495  IQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMI 542



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 63/281 (22%), Positives = 105/281 (37%), Gaps = 26/281 (9%)

Query: 95  LRGNPTPVVSWTRKKAPLVE--CNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQ 151
           ++G P P ++WT    P+++   ++ S     +   VS L I      D G Y CTA N 
Sbjct: 182 VKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 241

Query: 152 YGEAICSVYIQPEGXXXXX-----XXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR--QT 204
            G  +    I   G                  Y H    + +  Y  + Y          
Sbjct: 242 AGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHC-RVIGYPYYSIKWYKNSNLLPFNH 300

Query: 205 QKVAY-TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
           ++VA+  NGT   S    +VD  EY     V  + S ++       V ++ ++   + P 
Sbjct: 301 RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQ------SVHVTVKVPPFIQPF 354

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
             P+ +   R             V +SG+    +TW K+G+ +  S    I      ++L
Sbjct: 355 EFPRFSIGQRVFIPC--------VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSL 406

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           R+ N     +G+YT +A N    +     L V  P +  VQ
Sbjct: 407 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQ 447



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 8/120 (6%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV--- 3173
            DSG Y C+ +N  G A++S  +    K     P   T   N      GQ     CT    
Sbjct: 512  DSGYYLCKVSNDVG-ADVSKSMYLTVKI----PAMITSYPNTTLATQGQKKEMSCTAHGE 566

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+     K +   N +  R+    K V +     L I  T   DSG + C A N YGED
Sbjct: 567  KPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGED 626



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 490  APKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKD--GVPIIPNPELRIHTDGGAS 546
            AP  +  FS T+     + +VL  +AVG P+P + W KD  G P +   + R       S
Sbjct: 1036 APARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS 1095

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGS 571
             + I   KA D+ +Y C A N  GS
Sbjct: 1096 FI-IRTVKAEDSGYYSCIANNNWGS 1119



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
            RG  S+    EP+   P + +T   + T    + +   C+     DP   ++W ++    
Sbjct: 1021 RGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVG--DPSPAVKWMKDSNGT 1078

Query: 3873 PSGHRY---RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
            PS       R+++  G  S  I  V AEDSG Y C A N++G D     +  +  PD
Sbjct: 1079 PSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPD 1133



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            +G P+    WL++ +P+E S R           L ++ + P DSG+Y C   N  G A  
Sbjct: 1    LGHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTAKV 56

Query: 1797 SSTLFVQ 1803
               L+V+
Sbjct: 57   IGRLYVK 63



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/141 (21%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W  +   +E S R +     G+++  I   + +DSG+Y C  +N++G A++  +L     
Sbjct: 10   WLKDNMPLELSGRFQKTVT-GLLIENI---RPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 65

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             K      T   + ++    G      C+V   +  D ++ WY NG+ +     ++ ++ 
Sbjct: 66   LKA-----TISPRKVKS-SVGSQVSLSCSVTGTE--DQELSWYRNGEILNPGKNVR-ITG 116

Query: 3204 FGFVVLDIAYTQNHDSGEYVC 3224
                 L + +    D G Y C
Sbjct: 117  INHENLIMDHMVKSDGGAYQC 137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 43/190 (22%), Positives = 73/190 (38%), Gaps = 18/190 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL---VNESGNH 448
           P+FV   +D+D   GK    +C   G P P + W  +       +    L   +    N 
Sbjct: 442 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG 501

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEP 507
           +L+I +V   DSG   C   N  G    +     ++      P  +  + +T    +G+ 
Sbjct: 502 SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVK-----IPAMITSYPNTTLATQGQK 556

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT-------DGGASTLDIPRAKASDAAW 560
             ++  A G     + W+K+    I NPE+  +        +   STL I      D+ +
Sbjct: 557 KEMSCTAHGEKPIIVRWEKE--DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 614

Query: 561 YQCTAQNVAG 570
           + C A N  G
Sbjct: 615 FSCHAINSYG 624



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYV-ALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            GD  + + W KDGRP+  S  + T  N  +  +L I ++++   G+YTC A N       
Sbjct: 374  GDLPITITWQKDGRPIPGSLGV-TIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEH 432

Query: 996  SANLTIVTKKDIIAESQHPGGL 1017
             + L +      + + +   G+
Sbjct: 433  QSQLIVRVPPKFVVQPRDQDGI 454



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   +P++NI  I  G+  +  CR+I  G P   ++W++N  L+  + R     + G  +
Sbjct: 256  PASIRPMKNITAIA-GRDTYIHCRVI--GYPYYSIKWYKNSNLLPFNHRQVAFENNG--T 310

Query: 2436 MTISHVRDE-DEGVYMC 2451
            + +S V+ E DEG Y C
Sbjct: 311  LKLSDVQKEVDEGEYTC 327



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 5/67 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRI---RTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            GD S  ++W  +     +   I   R++++ G  ++  +  K  DSG YSC A N WG  
Sbjct: 1063 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV--KAEDSGYYSCIANNNWGSD 1120

Query: 3133 EISVKLE 3139
            EI + L+
Sbjct: 1121 EIILNLQ 1127



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  I  +K+ T          CRV     P   I+WY+N  LLP  HR     + G + L
Sbjct: 256  PASIRPMKNITAIAGRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 313

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              +     D GEY C  +       +++     K+P  I   + PR
Sbjct: 314  SDVQKEV-DEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR 358



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSG 3875
            +D  K   +    P  IT   + T+  ++G + E       +  + + W +  +++ P  
Sbjct: 526  ADVSKSMYLTVKIPAMITSYPNTTLA-TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEM 584

Query: 3876 HRY----RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             RY    + V +    +L IL    EDSG + C A+N +GED     ++ ++ PD
Sbjct: 585  ARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD 639



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 13/134 (9%)

Query: 3094 SHRI-RTVYAFGMVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPR 3150
            SHRI + + + G VV  L I  ++  D G Y C A N  G      ++        + P 
Sbjct: 204  SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV------RGPA 257

Query: 3151 FTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLD 3210
                ++NI  +  G+  +  C V+    P   I+WY N   +  + R     + G + L 
Sbjct: 258  SIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKLS 314

Query: 3211 IAYTQNHDSGEYVC 3224
                +  D GEY C
Sbjct: 315  -DVQKEVDEGEYTC 327



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 10/100 (10%)

Query: 3683 EEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRP--F 3738
            E IT+E     P R  +     +  P    +   C+   VGDP+  + W    NG P   
Sbjct: 1026 EIITVEPLAKAPARI-LTFSGTVTTPWMKDIVLPCKA--VGDPSPAVKWMKDSNGTPSLV 1082

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
                R    ++  FI   I  + A D+G Y+C A N WGS
Sbjct: 1083 TIDGRRSIFSNGSFI---IRTVKAEDSGYYSCIANNNWGS 1119



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKD--GRP--VEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD +  V+W+KD  G P  V    R + F N  ++  T+K+    D+G+Y+C A N  G
Sbjct: 1062 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKA---EDSGYYSCIANNNWG 1118

Query: 992  QATTSANLTIVTKKD 1006
                  NL +    D
Sbjct: 1119 SDEIILNLQVQVPPD 1133



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 4436 GEPLPLIKWYREN--FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            G+P P +KW +++   P   + D +   FS  S  IIR V  EDS  ++ +A N  G+ +
Sbjct: 1063 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF-IIRTVKAEDSGYYSCIANNNWGSDE 1121

Query: 4494 CSANLVVEEKRRQGR 4508
               NL V+    Q R
Sbjct: 1122 IILNLQVQVPPDQPR 1136



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 7/100 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKS----THDFSYVS 2832
            IS  +  V    + +   CNV+ +  PT  I W  ++ P+  G  ++     T + + VS
Sbjct: 162  ISAFSEKVVSPAEPVSLMCNVKGTPLPT--ITWTLDDDPILKGGSHRISQMITSEGNVVS 219

Query: 2833 -LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
             L+I+ +   D G+Y C A NS G       +   G  +I
Sbjct: 220  YLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI 259



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 7/99 (7%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH-RYRTSN-DFG- 1900
            P  IT     T  ++GQ     C    + +  + V W    +++     RY  S  + G 
Sbjct: 539  PAMITSYPNTTLATQGQKKEMSCTA--HGEKPIIVRWEKEDRIINPEMARYLVSTKEVGE 596

Query: 1901 --FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               + L IL    EDSG ++C AIN+ G+    I+L VQ
Sbjct: 597  EVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 635



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA----DEYTLRISEAFPEDEGDYKC 4695
            I   CK VG P P V+W K D    PS      R +      + +R  +A  ED G Y C
Sbjct: 1055 IVLPCKAVGDPSPAVKWMK-DSNGTPSLVTIDGRRSIFSNGSFIIRTVKA--EDSGYYSC 1111

Query: 4696 VAYNSAGRVTVAAKLKV-TQPDQ 4717
            +A N+ G   +   L+V   PDQ
Sbjct: 1112 IANNNWGSDEIILNLQVQVPPDQ 1134



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + P  I  +   T ++ G+  +  CR+  YP     ++WY N  +L   HR     + G 
Sbjct: 254  RGPASIRPMKNITAIA-GRDTYIHCRVIGYP--YYSIKWYKNSNLLPFNHRQVAFENNG- 309

Query: 1902 AALDILTVYGE-DSGEYTCKAI 1922
              L +  V  E D GEYTC  +
Sbjct: 310  -TLKLSDVQKEVDEGEYTCNVL 330



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 10/93 (10%)

Query: 663  VGDPTMKIEWLK--NG-QSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
            VGDP+  ++W+K  NG  S+       SIF  G  S  + ++  +DSG Y+C A +  G 
Sbjct: 1062 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGS 1119

Query: 720  AETKAVLHV-----TPRATIERTSQHPETLQYI 747
             E    L V      PR T+ +T+    TL ++
Sbjct: 1120 DEIILNLQVQVPPDQPRLTVSKTTSSSITLSWL 1152



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 7/80 (8%)

Query: 1471 VTDSNLKVEWFK--NGQP--VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            V D +  V+W K  NG P  VTI  R R I   G   +  +   AEDSG Y+C A N  G
Sbjct: 1062 VGDPSPAVKWMKDSNGTPSLVTIDGR-RSIFSNGSFIIRTVK--AEDSGYYSCIANNNWG 1118

Query: 1527 TDEVSCRLTCRSTTDIVRST 1546
            +DE+   L  +   D  R T
Sbjct: 1119 SDEIILNLQVQVPPDQPRLT 1138



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 9/94 (9%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG-----QPVTIGHRFR 1494
            V + P+FV +P+  ++ I G+ V   C  E      +  ++ K       QP+ +  R +
Sbjct: 438  VRVPPKFVVQPRD-QDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQ 496

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             + +   +   +++   EDSG Y C+  N VG D
Sbjct: 497  VLSNGSLLIKHVVE---EDSGYYLCKVSNDVGAD 527



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKD  P+E S R    F      L I+++   D+G Y C   N  G A     L +
Sbjct: 10   WLKDNMPLELSGR----FQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 62



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 1/98 (1%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V  + P F  P +  R +  Q   F   ++  GD  + + W ++G PI  S  +T  +  
Sbjct: 343  VTVKVPPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNID 401

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
               +L +  ++   +G YTC A NE       S L V+
Sbjct: 402  FTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR 439



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 35/171 (20%), Positives = 70/171 (40%), Gaps = 14/171 (8%)

Query: 3072 LIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            ++ +GD  + I W  +G+ I  S  +          L I       +G Y+C A N+   
Sbjct: 370  VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 429

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-- 3189
             E   +L          P+F    ++ +G+  G++    C+      P +  ++      
Sbjct: 430  VEHQSQLIV-----RVPPKFVVQPRDQDGIY-GKAVILNCSAEGYPVPTIVWKFSKGAGV 483

Query: 3190 ---QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
               QP+  + RI+ +S+   ++  +      DSG Y+C+  N  G D +++
Sbjct: 484  PQFQPIALNGRIQVLSNGSLLIKHVV---EEDSGYYLCKVSNDVGADVSKS 531



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 1613 WYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG 1665
            W  +N PL+   RF +T       L I +  P DSG+Y C   N  G A   G
Sbjct: 10   WLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTAKVIG 58



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P  I  ++++T +  G+  +   R++    P   ++W+ N   LP  HR   F + G + 
Sbjct: 256  PASIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLK 312

Query: 3342 LDILYCYEENSGEYEC 3357
            L  +   E + GEY C
Sbjct: 313  LSDVQ-KEVDEGEYTC 327



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
           T + P FI+P +       G+       +    D  + + W KDGRPI  S  +T I N 
Sbjct: 344 TVKVPPFIQPFE-FPRFSIGQRVFIPCVVVS-GDLPITITWQKDGRPIPGSLGVT-IDNI 400

Query: 826 GYV-SLNIMHLRAEDAGSYTVRAVNK 850
            +  SL I +L     G+YT  A N+
Sbjct: 401 DFTSSLRISNLSLMHNGNYTCIARNE 426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 5/106 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS- 695
           P FI P +      G ++ F   +   GD  + I W K+G+ I  S   T I    + S 
Sbjct: 348 PPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVT-IDNIDFTSS 405

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAE--TKAVLHVTPRATIERTSQ 739
           L + +L++  +G YTC A +     E  ++ ++ V P+  ++   Q
Sbjct: 406 LRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQ 451



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 13/92 (14%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW-FHNG------RPFATGSRVHT 3746
            PP+F V+ +D  D   G  V  +C  E  G P   I W F  G      +P A   R+  
Sbjct: 441  PPKFVVQPRDQ-DGIYGKAVILNCSAE--GYPVPTIVWKFSKGAGVPQFQPIALNGRIQV 497

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            L++   +   I ++   D+G Y C+ +N  G+
Sbjct: 498  LSNGSLL---IKHVVEEDSGYYLCKVSNDVGA 526


>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhesion
            molecule protein.
          Length = 2012

 Score =  112 bits (269), Expect = 3e-23
 Identities = 97/383 (25%), Positives = 160/383 (41%), Gaps = 43/383 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P  +W ++N P++ S  FQ     T + L+I  +   DS  +     NR GTAK  
Sbjct: 250  GHPEPDYRWLKDNMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVI 305

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              L V++          P   T++ + V  + G  V L   VTGT+  ++ W +NG+ + 
Sbjct: 306  GRLYVKQ----------PLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILN 355

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P  +N  +       L++      D G Y+C        A+   + V+            
Sbjct: 356  PG-KNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLE----------- 403

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKY--FQMS 4672
                +  P+II    +K+V+  + +   C + G PLPT+ W    D ++K   +   QM 
Sbjct: 404  ----DGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMI 459

Query: 4673 RTADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
             +       L IS +   D G Y+C A NSAG V   A++ V  P       ++ P+++I
Sbjct: 460  TSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGP------ASIRPMKNI 513

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                G+      ++      +I+W +   L+P     Q+  E N  + L     E D G 
Sbjct: 514  TAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGE 572

Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813
            +TC       Q+ TS  + V  K
Sbjct: 573  YTCNVLVQP-QLSTSQSVHVTVK 594



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 94/382 (24%), Positives = 145/382 (37%), Gaps = 34/382 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G PLP I W  ++ PI      +I    T    ++  + +  S V        GG  +C+
Sbjct: 432  GTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQV------RDGGVYRCT 485

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            AN        Q R  +  P+     +N+   +G+   +  +V G     + W KN   + 
Sbjct: 486  ANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLP 545

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
             + R    E +GT  L  ++    D G+Y C  +            V    +T       
Sbjct: 546  FNHRQVAFENNGTLKLSDVQK-EVDEGEYTCNVL------------VQPQLSTSQSVHVT 592

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRT 4674
             K     P  I+P +    + GQ +   C +V   LP T+ W K  + I  S    +   
Sbjct: 593  VKV----PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI 648

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +LRIS       G+Y C+A N A  V   ++L V  P +    P     RD     
Sbjct: 649  DFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP-----RDQDGIY 703

Query: 4735 GQPAQFKTQITSKIKPTIQW-LREGALIPETPDFQM---IHEGNNAVLLIGNTYEEDTGT 4790
            G+             PTI W   +GA +P+     +   I   +N  LLI +  EED+G 
Sbjct: 704  GKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGY 763

Query: 4791 FTCRATTAAG-QVETSAKLVVK 4811
            + C+ +   G  V  S  L VK
Sbjct: 764  YLCKVSNDVGADVSKSMYLTVK 785



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 79/336 (23%), Positives = 133/336 (39%), Gaps = 49/336 (14%)

Query: 235 SFRESITKRYVGESDVQIST-EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293
           + R S +  YV E   +  T ++   L    P K    PR  K   G+       ++G  
Sbjct: 282 NIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTE 341

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
              ++W++NG+ ++N  K+  IT  NH  L + +  KSD G Y         C V    L
Sbjct: 342 DQELSWYRNGE-ILNPGKNVRITGINHENLIMDHMVKSDGGAYQ--------CFVRKDKL 392

Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
           + +   +  ++D   + I+             SEK ++P              +     C
Sbjct: 393 SAQDYVQVVLEDGTPKIIS-----------AFSEKVVSP-------------AEPVSLMC 428

Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKI--LVNESGN--HALMITNVTLSDSGVVTCVARN 469
            V G P P +TW ++D  I    +H+I  ++   GN    L I++  + D GV  C A N
Sbjct: 429 NVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANN 488

Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
            +G   +Q R+N      V  P  +     +    G    ++ R +G P   I W K+  
Sbjct: 489 SAGVVLYQARIN------VRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNS- 541

Query: 530 PIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            ++P  + ++    +G     D+   K  D   Y C
Sbjct: 542 NLLPFNHRQVAFENNGTLKLSDV--QKEVDEGEYTC 575



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 55/178 (30%), Positives = 78/178 (43%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C VTG    E++W+ N   +    N +I      N  L++ ++  SD G   C
Sbjct: 328 GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQC 385

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
             R    + + Q  + V+ ++    PK +  FS   V   EPV L     GTP P ITW 
Sbjct: 386 FVRKD--KLSAQDYVQVVLEDGT--PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWT 441

Query: 526 KDGVPIIPNPELRIH---TDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+     RI    T  G   S L+I  ++  D   Y+CTA N AG    +AR+
Sbjct: 442 LDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 499



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 68/285 (23%), Positives = 115/285 (40%), Gaps = 31/285 (10%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V+G  PI + W K+G+ +   +   I   D T +L I       +G Y C+A N A    
Sbjct: 620  VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 679

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
              ++ +V +P               P  +++P +D+    G+A+  +C   G P+PT+ W
Sbjct: 680  HQSQLIVRVP---------------PKFVVQP-RDQDGIYGKAVILNCSAEGYPVPTIVW 723

Query: 4657 Y----KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLK 4711
                  G    +P       +     +L I     ED G Y C   N  G  V+ +  L 
Sbjct: 724  KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 783

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDF--- 4767
            V  P    + P  T     +  +GQ  +       +    ++W +E  +I PE   +   
Sbjct: 784  VKIPAMITSYPNTT-----LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 838

Query: 4768 -QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             + + E   + L I  T  ED+G F+C A  + G+     +L V+
Sbjct: 839  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 883



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 46/175 (26%), Positives = 72/175 (41%), Gaps = 10/175 (5%)

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
            AN+ P I++    +    GQ +E  CK +G P P  +W K +  ++ S  FQ + T    
Sbjct: 221  ANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG--- 277

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
             L I    P D G Y C   N  G   V  +L V QP +A   P     R +    G   
Sbjct: 278  -LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISP-----RKVKSSVGSQV 331

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                 +T      + W R G ++    + + I   N+  L++ +  + D G + C
Sbjct: 332  SLSCSVTGTEDQELSWYRNGEILNPGKNVR-ITGINHENLIMDHMVKSDGGAYQC 385



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 70/290 (24%), Positives = 114/290 (39%), Gaps = 30/290 (10%)

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
            +GQ V L  K  G    D  WLK+   ++   R    ++  T  LLI    P DSG Y C
Sbjct: 238  AGQRVELPCKALGHPEPDYRWLKDNMPLELSGR---FQKTVT-GLLIENIRPSDSGSYVC 293

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
               N  G A+      V  P          KA  +P ++    K  +   G  +  SC +
Sbjct: 294  EVSNRYGTAKVIGRLYVKQP---------LKATISPRKV----KSSV---GSQVSLSCSV 337

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G     + WY+  +++ P K  +++    E  L +      D G Y+C  +    +++ 
Sbjct: 338  TGTEDQELSWYRNGEILNPGKNVRITGINHE-NLIMDHMVKSDGGAYQC--FVRKDKLSA 394

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               ++V   D    +  ++   + VV   +P      +     PTI W  +   I +   
Sbjct: 395  QDYVQVVLEDGTPKI--ISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGS 452

Query: 4767 F---QMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                QMI    N V  L I ++   D G + C A  +AG V   A++ V+
Sbjct: 453  HRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR 502



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 73/287 (25%), Positives = 111/287 (38%), Gaps = 35/287 (12%)

Query: 4439 LPL-IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            LP+ I W ++  PI  S    I      S L I  + +  +  +  +A N     +  + 
Sbjct: 624  LPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQ 683

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKV-- 4554
            L+V           VPP F +  ++ +   G+ V L+    G     + W    G  V  
Sbjct: 684  LIVR----------VPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQ 733

Query: 4555 -QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
             QP   N  ++     +LLI     +DSG Y C   N  G     A+   S+  T   P 
Sbjct: 734  FQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG-----ADVSKSMYLTVKIPA 788

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP--SKYFQM 4671
              T   N            +  +GQ  E SC   G+    V+W K D++I P  ++Y   
Sbjct: 789  MITSYPNTT----------LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 838

Query: 4672 SRTADE---YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            ++   E    TL+I     ED G + C A NS G      +L V +P
Sbjct: 839  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP 885



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 19/209 (9%)

Query: 376 QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRD 434
           Q  T + + ++ K   P F++  +    + G+     C V     P  +TW  + R I  
Sbjct: 582 QLSTSQSVHVTVKV--PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPG 639

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
                I  N     +L I+N++L  +G  TC+ARN++     Q +L V      V PKFV
Sbjct: 640 SLGVTI-DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIV-----RVPPKFV 693

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKD---GV----PIIPNPELRIHTDGGAST 547
            +    +   G+ V+LN  A G P P I W+     GV    PI  N  +++ ++G   +
Sbjct: 694 VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG---S 750

Query: 548 LDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           L I      D+ +Y C   N  G+  +++
Sbjct: 751 LLIKHVVEEDSGYYLCKVSNDVGADVSKS 779



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 50/191 (26%), Positives = 80/191 (41%), Gaps = 14/191 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T   CRV G PY  + W+ N   +   +NH+ +  E+ N  L 
Sbjct: 504 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFEN-NGTLK 560

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +++V    D G  TC           Q +L+  +   V    P F++ F       G+ V
Sbjct: 561 LSDVQKEVDEGEYTC-------NVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRV 613

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +    V    P  ITWQKDG PI  +  + I      S+L I          Y C A+N
Sbjct: 614 FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARN 673

Query: 568 VAGSTATRARL 578
            A +   +++L
Sbjct: 674 EAAAVEHQSQL 684



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 50/199 (25%), Positives = 87/199 (43%), Gaps = 15/199 (7%)

Query: 367 RSQYITDTQQRETEERIEISEKA-LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           R +Y  +T+Q  +  R+ +S+ A  AP  +     R    G+     C+  G P P+  W
Sbjct: 200 RHRYTGETRQSNSA-RLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRW 258

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             ++  +  + + +     +G   L+I N+  SDSG   C   N+ G      RL V + 
Sbjct: 259 LKDNMPL--ELSGRFQKTVTG---LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 313

Query: 486 -EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            +  ++P+ V+  S++    G  V L+    GT    ++W ++G  + P   +RI T   
Sbjct: 314 LKATISPRKVK--SSV----GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI-TGIN 366

Query: 545 ASTLDIPRAKASDAAWYQC 563
              L +     SD   YQC
Sbjct: 367 HENLIMDHMVKSDGGAYQC 385



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 68/252 (26%), Positives = 95/252 (37%), Gaps = 35/252 (13%)

Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
            I   E   +EH++Q   RV         PP F  + +       +        +G P+P 
Sbjct: 670  IARNEAAAVEHQSQLIVRV---------PPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT 720

Query: 4442 IKWYRENFPIKNSPDFQ-------IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            I W          P FQ       I   S  S+LI + V  EDS  +     N  G A  
Sbjct: 721  IVWKFSKGA--GVPQFQPIALNGRIQVLSNGSLLI-KHVVEEDSGYYLCKVSNDVG-ADV 776

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            S ++ +  K        +P   T        T GQ   +     G KPI V W K  + +
Sbjct: 777  SKSMYLTVK--------IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRII 828

Query: 4555 QPD-----IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             P+     +  K + E+   TL IL    +DSG + C AINS GE R   +  V  P   
Sbjct: 829  NPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP--P 886

Query: 4610 DKPKPQTKAANA 4621
            D P+ + K   A
Sbjct: 887  DPPEIEIKDVKA 898



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 64/322 (19%), Positives = 110/322 (34%), Gaps = 24/322 (7%)

Query: 45  TRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVS 104
           TR   T      +   +    P   +P I +  F + +   G   +   K  G+P P   
Sbjct: 199 TRHRYTGETRQSNSARLFVSDPANSAPSILDG-FDHRKAMAGQRVELPCKALGHPEPDYR 257

Query: 105 WTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
           W +   PL    + S R+ +      LLI+ I P D G Y C   N+YG A      +  
Sbjct: 258 WLKDNMPL----ELSGRFQKTV--TGLLIENIRPSDSGSYVCEVSNRYGTA------KVI 305

Query: 165 GXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVD 224
           G              R V  +V  +   +   T  + ++     Y NG   +   + ++ 
Sbjct: 306 GRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS--WYRNGEILNPGKNVRIT 363

Query: 225 TFEYRLL---REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGA 281
              +  L     V       + +V +  +     +   L   +P KI        +    
Sbjct: 364 GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP-KIISAFSEKVVSPAE 422

Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI---ITTHNHTT--LRVRNTQKSDSGHY 336
                  + G P P +TW  +   ++    H I   IT+  +    L + ++Q  D G Y
Sbjct: 423 PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVY 482

Query: 337 TLLAENPNGCIVTSGYLAVESP 358
              A N  G ++    + V  P
Sbjct: 483 RCTANNSAGVVLYQARINVRGP 504



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 13/193 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-IRDDYNHKILVNESGNHAL 450
           P  V+V +D+    G +  F C +       +T    ++  +      + L+  +G  AL
Sbjct: 125 PYTVRV-EDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTG--AL 181

Query: 451 MITNVTLSDSGV-VTCVARNK-SGET--AFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            I +V   D      C+ R++ +GET  +   RL V +     AP  ++ F       G+
Sbjct: 182 YIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANS-APSILDGFDHRKAMAGQ 240

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            V L  +A+G P P   W KD +P+    EL        + L I   + SD+  Y C   
Sbjct: 241 RVELPCKALGHPEPDYRWLKDNMPL----ELSGRFQKTVTGLLIENIRPSDSGSYVCEVS 296

Query: 567 NVAGSTATRARLY 579
           N  G+     RLY
Sbjct: 297 NRYGTAKVIGRLY 309



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 4/93 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P+K++TA+ G   +   R+  +G P   I+W KN   +  + R  +    G + L
Sbjct: 504 PASIRPMKNITAIAGRDTYIHCRV--IGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 561

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             +   + D GEYTC  +    ++ +++V HVT
Sbjct: 562 SDVQKEV-DEGEYTCNVLVQPQLSTSQSV-HVT 592



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/108 (30%), Positives = 47/108 (43%), Gaps = 6/108 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW-YRNGKLLPSGHRYRT--- 3880
            IV  PPKF+ Q +       + V   C  E    P   I W +  G  +P          
Sbjct: 685  IVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT--IVWKFSKGAGVPQFQPIALNGR 742

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +  +   SL I +V  EDSG Y+C+  ND G D +K+     K+P +I
Sbjct: 743  IQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMI 790



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 63/281 (22%), Positives = 105/281 (37%), Gaps = 26/281 (9%)

Query: 95  LRGNPTPVVSWTRKKAPLVE--CNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQ 151
           ++G P P ++WT    P+++   ++ S     +   VS L I      D G Y CTA N 
Sbjct: 430 VKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 489

Query: 152 YGEAICSVYIQPEGXXXXX-----XXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR--QT 204
            G  +    I   G                  Y H    + +  Y  + Y          
Sbjct: 490 AGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHC-RVIGYPYYSIKWYKNSNLLPFNH 548

Query: 205 QKVAY-TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
           ++VA+  NGT   S    +VD  EY     V  + S ++       V ++ ++   + P 
Sbjct: 549 RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQ------SVHVTVKVPPFIQPF 602

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
             P+ +   R             V +SG+    +TW K+G+ +  S    I      ++L
Sbjct: 603 EFPRFSIGQRVFIPC--------VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSL 654

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           R+ N     +G+YT +A N    +     L V  P +  VQ
Sbjct: 655 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQ 695



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 8/120 (6%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV--- 3173
            DSG Y C+ +N  G A++S  +    K     P   T   N      GQ     CT    
Sbjct: 760  DSGYYLCKVSNDVG-ADVSKSMYLTVKI----PAMITSYPNTTLATQGQKKEMSCTAHGE 814

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+     K +   N +  R+    K V +     L I  T   DSG + C A N YGED
Sbjct: 815  KPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGED 874



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 490  APKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKD--GVPIIPNPELRIHTDGGAS 546
            AP  +  FS T+     + +VL  +AVG P+P + W KD  G P +   + R       S
Sbjct: 1284 APARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS 1343

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGS 571
             + I   KA D+ +Y C A N  GS
Sbjct: 1344 FI-IRTVKAEDSGYYSCIANNNWGS 1367



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 4/125 (3%)

Query: 243 RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
           RY GE+    S  +  S    S P I     + K   G   +   +  G+P P   W K+
Sbjct: 202 RYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKD 261

Query: 303 GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
              L  S + +   T     L + N + SDSG Y     N  G     G L V+ P ++ 
Sbjct: 262 NMPLELSGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKAT 317

Query: 363 VQDQR 367
           +  ++
Sbjct: 318 ISPRK 322



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
            RG  S+    EP+   P + +T   + T    + +   C+     DP   ++W ++    
Sbjct: 1269 RGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVG--DPSPAVKWMKDSNGT 1326

Query: 3873 PSGHRY---RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
            PS       R+++  G  S  I  V AEDSG Y C A N++G D     +  +  PD
Sbjct: 1327 PSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPD 1381



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            +G P+    WL++ +P+E S R           L ++ + P DSG+Y C   N  G A  
Sbjct: 249  LGHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTAKV 304

Query: 1797 SSTLFVQ 1803
               L+V+
Sbjct: 305  IGRLYVK 311



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/141 (21%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W  +   +E S R +     G+++  I   + +DSG+Y C  +N++G A++  +L     
Sbjct: 258  WLKDNMPLELSGRFQKTVT-GLLIENI---RPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 313

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             K      T   + ++    G      C+V   +  D ++ WY NG+ +     ++ ++ 
Sbjct: 314  LKA-----TISPRKVKS-SVGSQVSLSCSVTGTE--DQELSWYRNGEILNPGKNVR-ITG 364

Query: 3204 FGFVVLDIAYTQNHDSGEYVC 3224
                 L + +    D G Y C
Sbjct: 365  INHENLIMDHMVKSDGGAYQC 385



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 43/190 (22%), Positives = 73/190 (38%), Gaps = 18/190 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL---VNESGNH 448
           P+FV   +D+D   GK    +C   G P P + W  +       +    L   +    N 
Sbjct: 690 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG 749

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEP 507
           +L+I +V   DSG   C   N  G    +     ++      P  +  + +T    +G+ 
Sbjct: 750 SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVK-----IPAMITSYPNTTLATQGQK 804

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT-------DGGASTLDIPRAKASDAAW 560
             ++  A G     + W+K+    I NPE+  +        +   STL I      D+ +
Sbjct: 805 KEMSCTAHGEKPIIVRWEKE--DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 862

Query: 561 YQCTAQNVAG 570
           + C A N  G
Sbjct: 863 FSCHAINSYG 872



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYV-ALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            GD  + + W KDGRP+  S  + T  N  +  +L I ++++   G+YTC A N       
Sbjct: 622  GDLPITITWQKDGRPIPGSLGV-TIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEH 680

Query: 996  SANLTIVTKKDIIAESQHPGGL 1017
             + L +      + + +   G+
Sbjct: 681  QSQLIVRVPPKFVVQPRDQDGI 702



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   +P++NI  I  G+  +  CR+I  G P   ++W++N  L+  + R     + G  +
Sbjct: 504  PASIRPMKNITAIA-GRDTYIHCRVI--GYPYYSIKWYKNSNLLPFNHRQVAFENNG--T 558

Query: 2436 MTISHVRDE-DEGVYMC 2451
            + +S V+ E DEG Y C
Sbjct: 559  LKLSDVQKEVDEGEYTC 575



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 5/67 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRI---RTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            GD S  ++W  +     +   I   R++++ G  ++  +  K  DSG YSC A N WG  
Sbjct: 1311 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV--KAEDSGYYSCIANNNWGSD 1368

Query: 3133 EISVKLE 3139
            EI + L+
Sbjct: 1369 EIILNLQ 1375



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 7/104 (6%)

Query: 2623 EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG 2682
            E   +    +FV      AP        + K + GQ V L  +     +P+ +  W K+ 
Sbjct: 206  ETRQSNSARLFVSDPANSAPSILDGF-DHRKAMAGQRVELPCKALGHPEPDYR--WLKDN 262

Query: 2683 VTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            + L    R + T    +  L I ++R  DSG Y C+ +N  G A
Sbjct: 263  MPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTA 302



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  I  +K+ T          CRV     P   I+WY+N  LLP  HR     + G + L
Sbjct: 504  PASIRPMKNITAIAGRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 561

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              +     D GEY C  +       +++     K+P  I   + PR
Sbjct: 562  SDVQKEV-DEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR 606



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSG 3875
            +D  K   +    P  IT   + T+  ++G + E       +  + + W +  +++ P  
Sbjct: 774  ADVSKSMYLTVKIPAMITSYPNTTLA-TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEM 832

Query: 3876 HRY----RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             RY    + V +    +L IL    EDSG + C A+N +GED     ++ ++ PD
Sbjct: 833  ARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD 887



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 13/134 (9%)

Query: 3094 SHRI-RTVYAFGMVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPR 3150
            SHRI + + + G VV  L I  ++  D G Y C A N  G      ++        + P 
Sbjct: 452  SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV------RGPA 505

Query: 3151 FTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLD 3210
                ++NI  +  G+  +  C V+    P   I+WY N   +  + R     + G + L 
Sbjct: 506  SIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKLS 562

Query: 3211 IAYTQNHDSGEYVC 3224
                +  D GEY C
Sbjct: 563  -DVQKEVDEGEYTC 575



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 10/100 (10%)

Query: 3683 EEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRP--F 3738
            E IT+E     P R  +     +  P    +   C+   VGDP+  + W    NG P   
Sbjct: 1274 EIITVEPLAKAPARI-LTFSGTVTTPWMKDIVLPCKA--VGDPSPAVKWMKDSNGTPSLV 1330

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
                R    ++  FI   I  + A D+G Y+C A N WGS
Sbjct: 1331 TIDGRRSIFSNGSFI---IRTVKAEDSGYYSCIANNNWGS 1367



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKD--GRP--VEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD +  V+W+KD  G P  V    R + F N  ++  T+K+    D+G+Y+C A N  G
Sbjct: 1310 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKA---EDSGYYSCIANNNWG 1366

Query: 992  QATTSANLTIVTKKD 1006
                  NL +    D
Sbjct: 1367 SDEIILNLQVQVPPD 1381



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 4436 GEPLPLIKWYREN--FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            G+P P +KW +++   P   + D +   FS  S  IIR V  EDS  ++ +A N  G+ +
Sbjct: 1311 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF-IIRTVKAEDSGYYSCIANNNWGSDE 1369

Query: 4494 CSANLVVEEKRRQGR 4508
               NL V+    Q R
Sbjct: 1370 IILNLQVQVPPDQPR 1384



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 32/130 (24%), Positives = 48/130 (36%), Gaps = 13/130 (10%)

Query: 1543 VRSTQNEAGLEQIQVL-------EDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRA 1595
            ++  QNE GL   + +       E R        V +    AP       + +   GQR 
Sbjct: 183  IKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRV 242

Query: 1596 HFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAI 1655
                + +   +   +  W  +N PL+   RF +T       L I +  P DSG+Y C   
Sbjct: 243  ELPCKALGHPEPDYR--WLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVS 296

Query: 1656 NALGEAVTSG 1665
            N  G A   G
Sbjct: 297  NRYGTAKVIG 306



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 7/100 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKS----THDFSYVS 2832
            IS  +  V    + +   CNV+ +  PT  I W  ++ P+  G  ++     T + + VS
Sbjct: 410  ISAFSEKVVSPAEPVSLMCNVKGTPLPT--ITWTLDDDPILKGGSHRISQMITSEGNVVS 467

Query: 2833 -LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
             L+I+ +   D G+Y C A NS G       +   G  +I
Sbjct: 468  YLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI 507



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 7/99 (7%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH-RYRTSN-DFG- 1900
            P  IT     T  ++GQ     C    + +  + V W    +++     RY  S  + G 
Sbjct: 787  PAMITSYPNTTLATQGQKKEMSCTA--HGEKPIIVRWEKEDRIINPEMARYLVSTKEVGE 844

Query: 1901 --FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               + L IL    EDSG ++C AIN+ G+    I+L VQ
Sbjct: 845  EVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 883



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA----DEYTLRISEAFPEDEGDYKC 4695
            I   CK VG P P V+W K D    PS      R +      + +R  +A  ED G Y C
Sbjct: 1303 IVLPCKAVGDPSPAVKWMK-DSNGTPSLVTIDGRRSIFSNGSFIIRTVKA--EDSGYYSC 1359

Query: 4696 VAYNSAGRVTVAAKLKV-TQPDQ 4717
            +A N+ G   +   L+V   PDQ
Sbjct: 1360 IANNNWGSDEIILNLQVQVPPDQ 1382



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + P  I  +   T ++ G+  +  CR+  YP     ++WY N  +L   HR     + G 
Sbjct: 502  RGPASIRPMKNITAIA-GRDTYIHCRVIGYP--YYSIKWYKNSNLLPFNHRQVAFENNG- 557

Query: 1902 AALDILTVYGE-DSGEYTCKAI 1922
              L +  V  E D GEYTC  +
Sbjct: 558  -TLKLSDVQKEVDEGEYTCNVL 578



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 6/68 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            GQ     C+ +  G P     W ++   +E S R  KT       + I ++R  D G Y+
Sbjct: 239  GQRVELPCKAL--GHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYV 292

Query: 2451 CRASNLLG 2458
            C  SN  G
Sbjct: 293  CEVSNRYG 300



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 10/93 (10%)

Query: 663  VGDPTMKIEWLK--NG-QSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
            VGDP+  ++W+K  NG  S+       SIF  G  S  + ++  +DSG Y+C A +  G 
Sbjct: 1310 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGS 1367

Query: 720  AETKAVLHV-----TPRATIERTSQHPETLQYI 747
             E    L V      PR T+ +T+    TL ++
Sbjct: 1368 DEIILNLQVQVPPDQPRLTVSKTTSSSITLSWL 1400



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 7/80 (8%)

Query: 1471 VTDSNLKVEWFK--NGQP--VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            V D +  V+W K  NG P  VTI  R R I   G   +  +   AEDSG Y+C A N  G
Sbjct: 1310 VGDPSPAVKWMKDSNGTPSLVTIDGR-RSIFSNGSFIIRTVK--AEDSGYYSCIANNNWG 1366

Query: 1527 TDEVSCRLTCRSTTDIVRST 1546
            +DE+   L  +   D  R T
Sbjct: 1367 SDEIILNLQVQVPPDQPRLT 1386



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI-KTVSDFGFVVLDIAYTQNHDSGEY 3222
            GQ     C  +   +PD +  W  +  P+  S R  KTV+  G ++ +I   +  DSG Y
Sbjct: 239  GQRVELPCKALGHPEPDYR--WLKDNMPLELSGRFQKTVT--GLLIENI---RPSDSGSY 291

Query: 3223 VCRAYNKYG 3231
            VC   N+YG
Sbjct: 292  VCEVSNRYG 300



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 9/94 (9%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG-----QPVTIGHRFR 1494
            V + P+FV +P+  ++ I G+ V   C  E      +  ++ K       QP+ +  R +
Sbjct: 686  VRVPPKFVVQPRD-QDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQ 744

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             + +   +   +++   EDSG Y C+  N VG D
Sbjct: 745  VLSNGSLLIKHVVE---EDSGYYLCKVSNDVGAD 775



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKD  P+E S R    F      L I+++   D+G Y C   N  G A     L +
Sbjct: 258  WLKDNMPLELSGR----FQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 310



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 1/98 (1%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V  + P F  P +  R +  Q   F   ++  GD  + + W ++G PI  S  +T  +  
Sbjct: 591  VTVKVPPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNID 649

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
               +L +  ++   +G YTC A NE       S L V+
Sbjct: 650  FTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR 687



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP       + + + G  V L C+   +G       W  +  P++   RF+         
Sbjct: 224  APSILDGFDHRKAMAGQRVELPCKA--LGHPEPDYRWLKDNMPLELSGRFQKTV----TG 277

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEA 1394
            L + ++ P DSG Y C+ +N+ G A
Sbjct: 278  LLIENIRPSDSGSYVCEVSNRYGTA 302



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 35/171 (20%), Positives = 70/171 (40%), Gaps = 14/171 (8%)

Query: 3072 LIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            ++ +GD  + I W  +G+ I  S  +          L I       +G Y+C A N+   
Sbjct: 618  VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 677

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-- 3189
             E   +L          P+F    ++ +G+  G++    C+      P +  ++      
Sbjct: 678  VEHQSQLIV-----RVPPKFVVQPRDQDGIY-GKAVILNCSAEGYPVPTIVWKFSKGAGV 731

Query: 3190 ---QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
               QP+  + RI+ +S+   ++  +      DSG Y+C+  N  G D +++
Sbjct: 732  PQFQPIALNGRIQVLSNGSLLIKHVV---EEDSGYYLCKVSNDVGADVSKS 779



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P  I  ++++T +  G+  +   R++    P   ++W+ N   LP  HR   F + G + 
Sbjct: 504  PASIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLK 560

Query: 3342 LDILYCYEENSGEYEC 3357
            L  +   E + GEY C
Sbjct: 561  LSDVQ-KEVDEGEYTC 575



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
           T + P FI+P +       G+       +    D  + + W KDGRPI  S  +T I N 
Sbjct: 592 TVKVPPFIQPFE-FPRFSIGQRVFIPCVVVS-GDLPITITWQKDGRPIPGSLGVT-IDNI 648

Query: 826 GYV-SLNIMHLRAEDAGSYTVRAVNK 850
            +  SL I +L     G+YT  A N+
Sbjct: 649 DFTSSLRISNLSLMHNGNYTCIARNE 674



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 5/106 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS- 695
           P FI P +      G ++ F   +   GD  + I W K+G+ I  S   T I    + S 
Sbjct: 596 PPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVT-IDNIDFTSS 653

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAE--TKAVLHVTPRATIERTSQ 739
           L + +L++  +G YTC A +     E  ++ ++ V P+  ++   Q
Sbjct: 654 LRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQ 699



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 13/92 (14%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW-FHNG------RPFATGSRVHT 3746
            PP+F V+ +D  D   G  V  +C  E  G P   I W F  G      +P A   R+  
Sbjct: 689  PPKFVVQPRDQ-DGIYGKAVILNCSAE--GYPVPTIVWKFSKGAGVPQFQPIALNGRIQV 745

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            L++   +   I ++   D+G Y C+ +N  G+
Sbjct: 746  LSNGSLL---IKHVVEEDSGYYLCKVSNDVGA 774


>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhesion
            molecule protein.
          Length = 1571

 Score =  112 bits (269), Expect = 3e-23
 Identities = 97/383 (25%), Positives = 160/383 (41%), Gaps = 43/383 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P  +W ++N P++ S  FQ     T + L+I  +   DS  +     NR GTAK  
Sbjct: 250  GHPEPDYRWLKDNMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVI 305

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              L V++          P   T++ + V  + G  V L   VTGT+  ++ W +NG+ + 
Sbjct: 306  GRLYVKQ----------PLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILN 355

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P  +N  +       L++      D G Y+C        A+   + V+            
Sbjct: 356  PG-KNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLE----------- 403

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKY--FQMS 4672
                +  P+II    +K+V+  + +   C + G PLPT+ W    D ++K   +   QM 
Sbjct: 404  ----DGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMI 459

Query: 4673 RTADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
             +       L IS +   D G Y+C A NSAG V   A++ V  P       ++ P+++I
Sbjct: 460  TSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGP------ASIRPMKNI 513

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                G+      ++      +I+W +   L+P     Q+  E N  + L     E D G 
Sbjct: 514  TAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGE 572

Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813
            +TC       Q+ TS  + V  K
Sbjct: 573  YTCNVLVQP-QLSTSQSVHVTVK 594



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 94/382 (24%), Positives = 145/382 (37%), Gaps = 34/382 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G PLP I W  ++ PI      +I    T    ++  + +  S V        GG  +C+
Sbjct: 432  GTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQV------RDGGVYRCT 485

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            AN        Q R  +  P+     +N+   +G+   +  +V G     + W KN   + 
Sbjct: 486  ANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLP 545

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
             + R    E +GT  L  ++    D G+Y C  +            V    +T       
Sbjct: 546  FNHRQVAFENNGTLKLSDVQK-EVDEGEYTCNVL------------VQPQLSTSQSVHVT 592

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRT 4674
             K     P  I+P +    + GQ +   C +V   LP T+ W K  + I  S    +   
Sbjct: 593  VKV----PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI 648

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +LRIS       G+Y C+A N A  V   ++L V  P +    P     RD     
Sbjct: 649  DFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP-----RDQDGIY 703

Query: 4735 GQPAQFKTQITSKIKPTIQW-LREGALIPETPDFQM---IHEGNNAVLLIGNTYEEDTGT 4790
            G+             PTI W   +GA +P+     +   I   +N  LLI +  EED+G 
Sbjct: 704  GKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGY 763

Query: 4791 FTCRATTAAG-QVETSAKLVVK 4811
            + C+ +   G  V  S  L VK
Sbjct: 764  YLCKVSNDVGADVSKSMYLTVK 785



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 79/336 (23%), Positives = 133/336 (39%), Gaps = 49/336 (14%)

Query: 235 SFRESITKRYVGESDVQIST-EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293
           + R S +  YV E   +  T ++   L    P K    PR  K   G+       ++G  
Sbjct: 282 NIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTE 341

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
              ++W++NG+ ++N  K+  IT  NH  L + +  KSD G Y         C V    L
Sbjct: 342 DQELSWYRNGE-ILNPGKNVRITGINHENLIMDHMVKSDGGAYQ--------CFVRKDKL 392

Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
           + +   +  ++D   + I+             SEK ++P              +     C
Sbjct: 393 SAQDYVQVVLEDGTPKIIS-----------AFSEKVVSP-------------AEPVSLMC 428

Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKI--LVNESGN--HALMITNVTLSDSGVVTCVARN 469
            V G P P +TW ++D  I    +H+I  ++   GN    L I++  + D GV  C A N
Sbjct: 429 NVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANN 488

Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
            +G   +Q R+N      V  P  +     +    G    ++ R +G P   I W K+  
Sbjct: 489 SAGVVLYQARIN------VRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNS- 541

Query: 530 PIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            ++P  + ++    +G     D+   K  D   Y C
Sbjct: 542 NLLPFNHRQVAFENNGTLKLSDV--QKEVDEGEYTC 575



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 55/178 (30%), Positives = 78/178 (43%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C VTG    E++W+ N   +    N +I      N  L++ ++  SD G   C
Sbjct: 328 GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQC 385

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
             R    + + Q  + V+ ++    PK +  FS   V   EPV L     GTP P ITW 
Sbjct: 386 FVRKD--KLSAQDYVQVVLEDGT--PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWT 441

Query: 526 KDGVPIIPNPELRIH---TDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+     RI    T  G   S L+I  ++  D   Y+CTA N AG    +AR+
Sbjct: 442 LDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 499



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 68/285 (23%), Positives = 115/285 (40%), Gaps = 31/285 (10%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V+G  PI + W K+G+ +   +   I   D T +L I       +G Y C+A N A    
Sbjct: 620  VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 679

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
              ++ +V +P               P  +++P +D+    G+A+  +C   G P+PT+ W
Sbjct: 680  HQSQLIVRVP---------------PKFVVQP-RDQDGIYGKAVILNCSAEGYPVPTIVW 723

Query: 4657 Y----KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLK 4711
                  G    +P       +     +L I     ED G Y C   N  G  V+ +  L 
Sbjct: 724  KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 783

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDF--- 4767
            V  P    + P  T     +  +GQ  +       +    ++W +E  +I PE   +   
Sbjct: 784  VKIPAMITSYPNTT-----LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 838

Query: 4768 -QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             + + E   + L I  T  ED+G F+C A  + G+     +L V+
Sbjct: 839  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 883



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 46/175 (26%), Positives = 72/175 (41%), Gaps = 10/175 (5%)

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
            AN+ P I++    +    GQ +E  CK +G P P  +W K +  ++ S  FQ + T    
Sbjct: 221  ANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG--- 277

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
             L I    P D G Y C   N  G   V  +L V QP +A   P     R +    G   
Sbjct: 278  -LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISP-----RKVKSSVGSQV 331

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                 +T      + W R G ++    + + I   N+  L++ +  + D G + C
Sbjct: 332  SLSCSVTGTEDQELSWYRNGEILNPGKNVR-ITGINHENLIMDHMVKSDGGAYQC 385



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 70/290 (24%), Positives = 114/290 (39%), Gaps = 30/290 (10%)

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
            +GQ V L  K  G    D  WLK+   ++   R    ++  T  LLI    P DSG Y C
Sbjct: 238  AGQRVELPCKALGHPEPDYRWLKDNMPLELSGR---FQKTVT-GLLIENIRPSDSGSYVC 293

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
               N  G A+      V  P          KA  +P ++    K  +   G  +  SC +
Sbjct: 294  EVSNRYGTAKVIGRLYVKQP---------LKATISPRKV----KSSV---GSQVSLSCSV 337

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G     + WY+  +++ P K  +++    E  L +      D G Y+C  +    +++ 
Sbjct: 338  TGTEDQELSWYRNGEILNPGKNVRITGINHE-NLIMDHMVKSDGGAYQC--FVRKDKLSA 394

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               ++V   D    +  ++   + VV   +P      +     PTI W  +   I +   
Sbjct: 395  QDYVQVVLEDGTPKI--ISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGS 452

Query: 4767 F---QMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                QMI    N V  L I ++   D G + C A  +AG V   A++ V+
Sbjct: 453  HRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR 502



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 73/287 (25%), Positives = 111/287 (38%), Gaps = 35/287 (12%)

Query: 4439 LPL-IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            LP+ I W ++  PI  S    I      S L I  + +  +  +  +A N     +  + 
Sbjct: 624  LPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQ 683

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKV-- 4554
            L+V           VPP F +  ++ +   G+ V L+    G     + W    G  V  
Sbjct: 684  LIVR----------VPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQ 733

Query: 4555 -QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
             QP   N  ++     +LLI     +DSG Y C   N  G     A+   S+  T   P 
Sbjct: 734  FQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG-----ADVSKSMYLTVKIPA 788

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP--SKYFQM 4671
              T   N            +  +GQ  E SC   G+    V+W K D++I P  ++Y   
Sbjct: 789  MITSYPNTT----------LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 838

Query: 4672 SRTADE---YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            ++   E    TL+I     ED G + C A NS G      +L V +P
Sbjct: 839  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP 885



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 19/209 (9%)

Query: 376 QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRD 434
           Q  T + + ++ K   P F++  +    + G+     C V     P  +TW  + R I  
Sbjct: 582 QLSTSQSVHVTVKV--PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPG 639

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
                I  N     +L I+N++L  +G  TC+ARN++     Q +L V      V PKFV
Sbjct: 640 SLGVTI-DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIV-----RVPPKFV 693

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKD---GV----PIIPNPELRIHTDGGAST 547
            +    +   G+ V+LN  A G P P I W+     GV    PI  N  +++ ++G   +
Sbjct: 694 VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG---S 750

Query: 548 LDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           L I      D+ +Y C   N  G+  +++
Sbjct: 751 LLIKHVVEEDSGYYLCKVSNDVGADVSKS 779



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 50/191 (26%), Positives = 80/191 (41%), Gaps = 14/191 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T   CRV G PY  + W+ N   +   +NH+ +  E+ N  L 
Sbjct: 504 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFEN-NGTLK 560

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +++V    D G  TC           Q +L+  +   V    P F++ F       G+ V
Sbjct: 561 LSDVQKEVDEGEYTC-------NVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRV 613

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +    V    P  ITWQKDG PI  +  + I      S+L I          Y C A+N
Sbjct: 614 FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARN 673

Query: 568 VAGSTATRARL 578
            A +   +++L
Sbjct: 674 EAAAVEHQSQL 684



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 50/199 (25%), Positives = 87/199 (43%), Gaps = 15/199 (7%)

Query: 367 RSQYITDTQQRETEERIEISEKA-LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           R +Y  +T+Q  +  R+ +S+ A  AP  +     R    G+     C+  G P P+  W
Sbjct: 200 RHRYTGETRQSNSA-RLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRW 258

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             ++  +  + + +     +G   L+I N+  SDSG   C   N+ G      RL V + 
Sbjct: 259 LKDNMPL--ELSGRFQKTVTG---LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 313

Query: 486 -EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            +  ++P+ V+  S++    G  V L+    GT    ++W ++G  + P   +RI T   
Sbjct: 314 LKATISPRKVK--SSV----GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI-TGIN 366

Query: 545 ASTLDIPRAKASDAAWYQC 563
              L +     SD   YQC
Sbjct: 367 HENLIMDHMVKSDGGAYQC 385



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 68/252 (26%), Positives = 95/252 (37%), Gaps = 35/252 (13%)

Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
            I   E   +EH++Q   RV         PP F  + +       +        +G P+P 
Sbjct: 670  IARNEAAAVEHQSQLIVRV---------PPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT 720

Query: 4442 IKWYRENFPIKNSPDFQ-------IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            I W          P FQ       I   S  S+LI + V  EDS  +     N  G A  
Sbjct: 721  IVWKFSKGA--GVPQFQPIALNGRIQVLSNGSLLI-KHVVEEDSGYYLCKVSNDVG-ADV 776

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            S ++ +  K        +P   T        T GQ   +     G KPI V W K  + +
Sbjct: 777  SKSMYLTVK--------IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRII 828

Query: 4555 QPD-----IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             P+     +  K + E+   TL IL    +DSG + C AINS GE R   +  V  P   
Sbjct: 829  NPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP--P 886

Query: 4610 DKPKPQTKAANA 4621
            D P+ + K   A
Sbjct: 887  DPPEIEIKDVKA 898



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 64/322 (19%), Positives = 110/322 (34%), Gaps = 24/322 (7%)

Query: 45  TRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVS 104
           TR   T      +   +    P   +P I +  F + +   G   +   K  G+P P   
Sbjct: 199 TRHRYTGETRQSNSARLFVSDPANSAPSILDG-FDHRKAMAGQRVELPCKALGHPEPDYR 257

Query: 105 WTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
           W +   PL    + S R+ +      LLI+ I P D G Y C   N+YG A      +  
Sbjct: 258 WLKDNMPL----ELSGRFQKTV--TGLLIENIRPSDSGSYVCEVSNRYGTA------KVI 305

Query: 165 GXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVD 224
           G              R V  +V  +   +   T  + ++     Y NG   +   + ++ 
Sbjct: 306 GRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS--WYRNGEILNPGKNVRIT 363

Query: 225 TFEYRLL---REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGA 281
              +  L     V       + +V +  +     +   L   +P KI        +    
Sbjct: 364 GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP-KIISAFSEKVVSPAE 422

Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI---ITTHNHTT--LRVRNTQKSDSGHY 336
                  + G P P +TW  +   ++    H I   IT+  +    L + ++Q  D G Y
Sbjct: 423 PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVY 482

Query: 337 TLLAENPNGCIVTSGYLAVESP 358
              A N  G ++    + V  P
Sbjct: 483 RCTANNSAGVVLYQARINVRGP 504



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 13/193 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-IRDDYNHKILVNESGNHAL 450
           P  V+V +D+    G +  F C +       +T    ++  +      + L+  +G  AL
Sbjct: 125 PYTVRV-EDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTG--AL 181

Query: 451 MITNVTLSDSGV-VTCVARNK-SGET--AFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            I +V   D      C+ R++ +GET  +   RL V +     AP  ++ F       G+
Sbjct: 182 YIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANS-APSILDGFDHRKAMAGQ 240

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            V L  +A+G P P   W KD +P+    EL        + L I   + SD+  Y C   
Sbjct: 241 RVELPCKALGHPEPDYRWLKDNMPL----ELSGRFQKTVTGLLIENIRPSDSGSYVCEVS 296

Query: 567 NVAGSTATRARLY 579
           N  G+     RLY
Sbjct: 297 NRYGTAKVIGRLY 309



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 4/93 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P+K++TA+ G   +   R+  +G P   I+W KN   +  + R  +    G + L
Sbjct: 504 PASIRPMKNITAIAGRDTYIHCRV--IGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 561

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             +   + D GEYTC  +    ++ +++V HVT
Sbjct: 562 SDVQKEV-DEGEYTCNVLVQPQLSTSQSV-HVT 592



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/108 (30%), Positives = 47/108 (43%), Gaps = 6/108 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW-YRNGKLLPSGHRYRT--- 3880
            IV  PPKF+ Q +       + V   C  E    P   I W +  G  +P          
Sbjct: 685  IVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT--IVWKFSKGAGVPQFQPIALNGR 742

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +  +   SL I +V  EDSG Y+C+  ND G D +K+     K+P +I
Sbjct: 743  IQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMI 790



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 63/281 (22%), Positives = 105/281 (37%), Gaps = 26/281 (9%)

Query: 95  LRGNPTPVVSWTRKKAPLVE--CNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQ 151
           ++G P P ++WT    P+++   ++ S     +   VS L I      D G Y CTA N 
Sbjct: 430 VKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 489

Query: 152 YGEAICSVYIQPEGXXXXX-----XXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR--QT 204
            G  +    I   G                  Y H    + +  Y  + Y          
Sbjct: 490 AGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHC-RVIGYPYYSIKWYKNSNLLPFNH 548

Query: 205 QKVAY-TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
           ++VA+  NGT   S    +VD  EY     V  + S ++       V ++ ++   + P 
Sbjct: 549 RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQ------SVHVTVKVPPFIQPF 602

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
             P+ +   R             V +SG+    +TW K+G+ +  S    I      ++L
Sbjct: 603 EFPRFSIGQRVFIPC--------VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSL 654

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           R+ N     +G+YT +A N    +     L V  P +  VQ
Sbjct: 655 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQ 695



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 8/120 (6%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV--- 3173
            DSG Y C+ +N  G A++S  +    K     P   T   N      GQ     CT    
Sbjct: 760  DSGYYLCKVSNDVG-ADVSKSMYLTVKI----PAMITSYPNTTLATQGQKKEMSCTAHGE 814

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+     K +   N +  R+    K V +     L I  T   DSG + C A N YGED
Sbjct: 815  KPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGED 874



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 490  APKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKD--GVPIIPNPELRIHTDGGAS 546
            AP  +  FS T+     + +VL  +AVG P+P + W KD  G P +   + R       S
Sbjct: 1284 APARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS 1343

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGS 571
             + I   KA D+ +Y C A N  GS
Sbjct: 1344 FI-IRTVKAEDSGYYSCIANNNWGS 1367



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 4/125 (3%)

Query: 243 RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
           RY GE+    S  +  S    S P I     + K   G   +   +  G+P P   W K+
Sbjct: 202 RYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKD 261

Query: 303 GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
              L  S + +   T     L + N + SDSG Y     N  G     G L V+ P ++ 
Sbjct: 262 NMPLELSGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKAT 317

Query: 363 VQDQR 367
           +  ++
Sbjct: 318 ISPRK 322



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
            RG  S+    EP+   P + +T   + T    + +   C+     DP   ++W ++    
Sbjct: 1269 RGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVG--DPSPAVKWMKDSNGT 1326

Query: 3873 PSGHRY---RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
            PS       R+++  G  S  I  V AEDSG Y C A N++G D     +  +  PD
Sbjct: 1327 PSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPD 1381



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            +G P+    WL++ +P+E S R           L ++ + P DSG+Y C   N  G A  
Sbjct: 249  LGHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTAKV 304

Query: 1797 SSTLFVQ 1803
               L+V+
Sbjct: 305  IGRLYVK 311



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/141 (21%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W  +   +E S R +     G+++  I   + +DSG+Y C  +N++G A++  +L     
Sbjct: 258  WLKDNMPLELSGRFQKTVT-GLLIENI---RPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 313

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             K      T   + ++    G      C+V   +  D ++ WY NG+ +     ++ ++ 
Sbjct: 314  LKA-----TISPRKVKS-SVGSQVSLSCSVTGTE--DQELSWYRNGEILNPGKNVR-ITG 364

Query: 3204 FGFVVLDIAYTQNHDSGEYVC 3224
                 L + +    D G Y C
Sbjct: 365  INHENLIMDHMVKSDGGAYQC 385



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 43/190 (22%), Positives = 73/190 (38%), Gaps = 18/190 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL---VNESGNH 448
           P+FV   +D+D   GK    +C   G P P + W  +       +    L   +    N 
Sbjct: 690 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG 749

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEP 507
           +L+I +V   DSG   C   N  G    +     ++      P  +  + +T    +G+ 
Sbjct: 750 SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVK-----IPAMITSYPNTTLATQGQK 804

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT-------DGGASTLDIPRAKASDAAW 560
             ++  A G     + W+K+    I NPE+  +        +   STL I      D+ +
Sbjct: 805 KEMSCTAHGEKPIIVRWEKE--DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 862

Query: 561 YQCTAQNVAG 570
           + C A N  G
Sbjct: 863 FSCHAINSYG 872



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYV-ALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            GD  + + W KDGRP+  S  + T  N  +  +L I ++++   G+YTC A N       
Sbjct: 622  GDLPITITWQKDGRPIPGSLGV-TIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEH 680

Query: 996  SANLTIVTKKDIIAESQHPGGL 1017
             + L +      + + +   G+
Sbjct: 681  QSQLIVRVPPKFVVQPRDQDGI 702



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   +P++NI  I  G+  +  CR+I  G P   ++W++N  L+  + R     + G  +
Sbjct: 504  PASIRPMKNITAIA-GRDTYIHCRVI--GYPYYSIKWYKNSNLLPFNHRQVAFENNG--T 558

Query: 2436 MTISHVRDE-DEGVYMC 2451
            + +S V+ E DEG Y C
Sbjct: 559  LKLSDVQKEVDEGEYTC 575



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 5/67 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRI---RTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            GD S  ++W  +     +   I   R++++ G  ++  +  K  DSG YSC A N WG  
Sbjct: 1311 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV--KAEDSGYYSCIANNNWGSD 1368

Query: 3133 EISVKLE 3139
            EI + L+
Sbjct: 1369 EIILNLQ 1375



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 7/104 (6%)

Query: 2623 EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG 2682
            E   +    +FV      AP        + K + GQ V L  +     +P+ +  W K+ 
Sbjct: 206  ETRQSNSARLFVSDPANSAPSILDGF-DHRKAMAGQRVELPCKALGHPEPDYR--WLKDN 262

Query: 2683 VTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            + L    R + T    +  L I ++R  DSG Y C+ +N  G A
Sbjct: 263  MPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTA 302



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  I  +K+ T          CRV     P   I+WY+N  LLP  HR     + G + L
Sbjct: 504  PASIRPMKNITAIAGRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 561

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              +     D GEY C  +       +++     K+P  I   + PR
Sbjct: 562  SDVQKEV-DEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR 606



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSG 3875
            +D  K   +    P  IT   + T+  ++G + E       +  + + W +  +++ P  
Sbjct: 774  ADVSKSMYLTVKIPAMITSYPNTTLA-TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEM 832

Query: 3876 HRY----RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             RY    + V +    +L IL    EDSG + C A+N +GED     ++ ++ PD
Sbjct: 833  ARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD 887



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 13/134 (9%)

Query: 3094 SHRI-RTVYAFGMVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPR 3150
            SHRI + + + G VV  L I  ++  D G Y C A N  G      ++        + P 
Sbjct: 452  SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV------RGPA 505

Query: 3151 FTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLD 3210
                ++NI  +  G+  +  C V+    P   I+WY N   +  + R     + G + L 
Sbjct: 506  SIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKLS 562

Query: 3211 IAYTQNHDSGEYVC 3224
                +  D GEY C
Sbjct: 563  -DVQKEVDEGEYTC 575



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 10/100 (10%)

Query: 3683 EEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRP--F 3738
            E IT+E     P R  +     +  P    +   C+   VGDP+  + W    NG P   
Sbjct: 1274 EIITVEPLAKAPARI-LTFSGTVTTPWMKDIVLPCKA--VGDPSPAVKWMKDSNGTPSLV 1330

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
                R    ++  FI   I  + A D+G Y+C A N WGS
Sbjct: 1331 TIDGRRSIFSNGSFI---IRTVKAEDSGYYSCIANNNWGS 1367



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKD--GRP--VEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD +  V+W+KD  G P  V    R + F N  ++  T+K+    D+G+Y+C A N  G
Sbjct: 1310 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKA---EDSGYYSCIANNNWG 1366

Query: 992  QATTSANLTIVTKKD 1006
                  NL +    D
Sbjct: 1367 SDEIILNLQVQVPPD 1381



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 4436 GEPLPLIKWYREN--FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            G+P P +KW +++   P   + D +   FS  S  IIR V  EDS  ++ +A N  G+ +
Sbjct: 1311 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF-IIRTVKAEDSGYYSCIANNNWGSDE 1369

Query: 4494 CSANLVVEEKRRQGR 4508
               NL V+    Q R
Sbjct: 1370 IILNLQVQVPPDQPR 1384



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 32/130 (24%), Positives = 48/130 (36%), Gaps = 13/130 (10%)

Query: 1543 VRSTQNEAGLEQIQVL-------EDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRA 1595
            ++  QNE GL   + +       E R        V +    AP       + +   GQR 
Sbjct: 183  IKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRV 242

Query: 1596 HFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAI 1655
                + +   +   +  W  +N PL+   RF +T       L I +  P DSG+Y C   
Sbjct: 243  ELPCKALGHPEPDYR--WLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVS 296

Query: 1656 NALGEAVTSG 1665
            N  G A   G
Sbjct: 297  NRYGTAKVIG 306



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 7/100 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKS----THDFSYVS 2832
            IS  +  V    + +   CNV+ +  PT  I W  ++ P+  G  ++     T + + VS
Sbjct: 410  ISAFSEKVVSPAEPVSLMCNVKGTPLPT--ITWTLDDDPILKGGSHRISQMITSEGNVVS 467

Query: 2833 -LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
             L+I+ +   D G+Y C A NS G       +   G  +I
Sbjct: 468  YLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI 507



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 7/99 (7%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH-RYRTSN-DFG- 1900
            P  IT     T  ++GQ     C    + +  + V W    +++     RY  S  + G 
Sbjct: 787  PAMITSYPNTTLATQGQKKEMSCTA--HGEKPIIVRWEKEDRIINPEMARYLVSTKEVGE 844

Query: 1901 --FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               + L IL    EDSG ++C AIN+ G+    I+L VQ
Sbjct: 845  EVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 883



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA----DEYTLRISEAFPEDEGDYKC 4695
            I   CK VG P P V+W K D    PS      R +      + +R  +A  ED G Y C
Sbjct: 1303 IVLPCKAVGDPSPAVKWMK-DSNGTPSLVTIDGRRSIFSNGSFIIRTVKA--EDSGYYSC 1359

Query: 4696 VAYNSAGRVTVAAKLKV-TQPDQ 4717
            +A N+ G   +   L+V   PDQ
Sbjct: 1360 IANNNWGSDEIILNLQVQVPPDQ 1382



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + P  I  +   T ++ G+  +  CR+  YP     ++WY N  +L   HR     + G 
Sbjct: 502  RGPASIRPMKNITAIA-GRDTYIHCRVIGYP--YYSIKWYKNSNLLPFNHRQVAFENNG- 557

Query: 1902 AALDILTVYGE-DSGEYTCKAI 1922
              L +  V  E D GEYTC  +
Sbjct: 558  -TLKLSDVQKEVDEGEYTCNVL 578



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 6/68 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            GQ     C+ +  G P     W ++   +E S R  KT       + I ++R  D G Y+
Sbjct: 239  GQRVELPCKAL--GHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYV 292

Query: 2451 CRASNLLG 2458
            C  SN  G
Sbjct: 293  CEVSNRYG 300



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 10/93 (10%)

Query: 663  VGDPTMKIEWLK--NG-QSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
            VGDP+  ++W+K  NG  S+       SIF  G  S  + ++  +DSG Y+C A +  G 
Sbjct: 1310 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGS 1367

Query: 720  AETKAVLHV-----TPRATIERTSQHPETLQYI 747
             E    L V      PR T+ +T+    TL ++
Sbjct: 1368 DEIILNLQVQVPPDQPRLTVSKTTSSSITLSWL 1400



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 7/80 (8%)

Query: 1471 VTDSNLKVEWFK--NGQP--VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            V D +  V+W K  NG P  VTI  R R I   G   +  +   AEDSG Y+C A N  G
Sbjct: 1310 VGDPSPAVKWMKDSNGTPSLVTIDGR-RSIFSNGSFIIRTVK--AEDSGYYSCIANNNWG 1366

Query: 1527 TDEVSCRLTCRSTTDIVRST 1546
            +DE+   L  +   D  R T
Sbjct: 1367 SDEIILNLQVQVPPDQPRLT 1386



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI-KTVSDFGFVVLDIAYTQNHDSGEY 3222
            GQ     C  +   +PD +  W  +  P+  S R  KTV+  G ++ +I   +  DSG Y
Sbjct: 239  GQRVELPCKALGHPEPDYR--WLKDNMPLELSGRFQKTVT--GLLIENI---RPSDSGSY 291

Query: 3223 VCRAYNKYG 3231
            VC   N+YG
Sbjct: 292  VCEVSNRYG 300



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 9/94 (9%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG-----QPVTIGHRFR 1494
            V + P+FV +P+  ++ I G+ V   C  E      +  ++ K       QP+ +  R +
Sbjct: 686  VRVPPKFVVQPRD-QDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQ 744

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             + +   +   +++   EDSG Y C+  N VG D
Sbjct: 745  VLSNGSLLIKHVVE---EDSGYYLCKVSNDVGAD 775



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKD  P+E S R    F      L I+++   D+G Y C   N  G A     L +
Sbjct: 258  WLKDNMPLELSGR----FQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 310



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 1/98 (1%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V  + P F  P +  R +  Q   F   ++  GD  + + W ++G PI  S  +T  +  
Sbjct: 591  VTVKVPPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNID 649

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
               +L +  ++   +G YTC A NE       S L V+
Sbjct: 650  FTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR 687



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP       + + + G  V L C+   +G       W  +  P++   RF+         
Sbjct: 224  APSILDGFDHRKAMAGQRVELPCKA--LGHPEPDYRWLKDNMPLELSGRFQKTV----TG 277

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEA 1394
            L + ++ P DSG Y C+ +N+ G A
Sbjct: 278  LLIENIRPSDSGSYVCEVSNRYGTA 302



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 35/171 (20%), Positives = 70/171 (40%), Gaps = 14/171 (8%)

Query: 3072 LIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            ++ +GD  + I W  +G+ I  S  +          L I       +G Y+C A N+   
Sbjct: 618  VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 677

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-- 3189
             E   +L          P+F    ++ +G+  G++    C+      P +  ++      
Sbjct: 678  VEHQSQLIV-----RVPPKFVVQPRDQDGIY-GKAVILNCSAEGYPVPTIVWKFSKGAGV 731

Query: 3190 ---QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
               QP+  + RI+ +S+   ++  +      DSG Y+C+  N  G D +++
Sbjct: 732  PQFQPIALNGRIQVLSNGSLLIKHVV---EEDSGYYLCKVSNDVGADVSKS 779



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P  I  ++++T +  G+  +   R++    P   ++W+ N   LP  HR   F + G + 
Sbjct: 504  PASIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLK 560

Query: 3342 LDILYCYEENSGEYEC 3357
            L  +   E + GEY C
Sbjct: 561  LSDVQ-KEVDEGEYTC 575



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
           T + P FI+P +       G+       +    D  + + W KDGRPI  S  +T I N 
Sbjct: 592 TVKVPPFIQPFE-FPRFSIGQRVFIPCVVVS-GDLPITITWQKDGRPIPGSLGVT-IDNI 648

Query: 826 GYV-SLNIMHLRAEDAGSYTVRAVNK 850
            +  SL I +L     G+YT  A N+
Sbjct: 649 DFTSSLRISNLSLMHNGNYTCIARNE 674



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 5/106 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS- 695
           P FI P +      G ++ F   +   GD  + I W K+G+ I  S   T I    + S 
Sbjct: 596 PPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVT-IDNIDFTSS 653

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAE--TKAVLHVTPRATIERTSQ 739
           L + +L++  +G YTC A +     E  ++ ++ V P+  ++   Q
Sbjct: 654 LRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQ 699



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 13/92 (14%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW-FHNG------RPFATGSRVHT 3746
            PP+F V+ +D  D   G  V  +C  E  G P   I W F  G      +P A   R+  
Sbjct: 689  PPKFVVQPRDQ-DGIYGKAVILNCSAE--GYPVPTIVWKFSKGAGVPQFQPIALNGRIQV 745

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            L++   +   I ++   D+G Y C+ +N  G+
Sbjct: 746  LSNGSLL---IKHVVEEDSGYYLCKVSNDVGA 774


>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhesion
            molecule protein.
          Length = 1896

 Score =  112 bits (269), Expect = 3e-23
 Identities = 97/383 (25%), Positives = 160/383 (41%), Gaps = 43/383 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P  +W ++N P++ S  FQ     T + L+I  +   DS  +     NR GTAK  
Sbjct: 236  GHPEPDYRWLKDNMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVI 291

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              L V++          P   T++ + V  + G  V L   VTGT+  ++ W +NG+ + 
Sbjct: 292  GRLYVKQ----------PLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILN 341

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P  +N  +       L++      D G Y+C        A+   + V+            
Sbjct: 342  PG-KNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLE----------- 389

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKY--FQMS 4672
                +  P+II    +K+V+  + +   C + G PLPT+ W    D ++K   +   QM 
Sbjct: 390  ----DGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMI 445

Query: 4673 RTADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
             +       L IS +   D G Y+C A NSAG V   A++ V  P       ++ P+++I
Sbjct: 446  TSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGP------ASIRPMKNI 499

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                G+      ++      +I+W +   L+P     Q+  E N  + L     E D G 
Sbjct: 500  TAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGE 558

Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813
            +TC       Q+ TS  + V  K
Sbjct: 559  YTCNVLVQP-QLSTSQSVHVTVK 580



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 94/382 (24%), Positives = 145/382 (37%), Gaps = 34/382 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G PLP I W  ++ PI      +I    T    ++  + +  S V        GG  +C+
Sbjct: 418  GTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQV------RDGGVYRCT 471

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            AN        Q R  +  P+     +N+   +G+   +  +V G     + W KN   + 
Sbjct: 472  ANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLP 531

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
             + R    E +GT  L  ++    D G+Y C  +            V    +T       
Sbjct: 532  FNHRQVAFENNGTLKLSDVQK-EVDEGEYTCNVL------------VQPQLSTSQSVHVT 578

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRT 4674
             K     P  I+P +    + GQ +   C +V   LP T+ W K  + I  S    +   
Sbjct: 579  VKV----PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI 634

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +LRIS       G+Y C+A N A  V   ++L V  P +    P     RD     
Sbjct: 635  DFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP-----RDQDGIY 689

Query: 4735 GQPAQFKTQITSKIKPTIQW-LREGALIPETPDFQM---IHEGNNAVLLIGNTYEEDTGT 4790
            G+             PTI W   +GA +P+     +   I   +N  LLI +  EED+G 
Sbjct: 690  GKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGY 749

Query: 4791 FTCRATTAAG-QVETSAKLVVK 4811
            + C+ +   G  V  S  L VK
Sbjct: 750  YLCKVSNDVGADVSKSMYLTVK 771



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 79/336 (23%), Positives = 133/336 (39%), Gaps = 49/336 (14%)

Query: 235 SFRESITKRYVGESDVQIST-EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293
           + R S +  YV E   +  T ++   L    P K    PR  K   G+       ++G  
Sbjct: 268 NIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTE 327

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
              ++W++NG+ ++N  K+  IT  NH  L + +  KSD G Y         C V    L
Sbjct: 328 DQELSWYRNGE-ILNPGKNVRITGINHENLIMDHMVKSDGGAYQ--------CFVRKDKL 378

Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
           + +   +  ++D   + I+             SEK ++P              +     C
Sbjct: 379 SAQDYVQVVLEDGTPKIIS-----------AFSEKVVSP-------------AEPVSLMC 414

Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKI--LVNESGN--HALMITNVTLSDSGVVTCVARN 469
            V G P P +TW ++D  I    +H+I  ++   GN    L I++  + D GV  C A N
Sbjct: 415 NVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANN 474

Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
            +G   +Q R+N      V  P  +     +    G    ++ R +G P   I W K+  
Sbjct: 475 SAGVVLYQARIN------VRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNS- 527

Query: 530 PIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            ++P  + ++    +G     D+   K  D   Y C
Sbjct: 528 NLLPFNHRQVAFENNGTLKLSDV--QKEVDEGEYTC 561



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 55/178 (30%), Positives = 78/178 (43%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C VTG    E++W+ N   +    N +I      N  L++ ++  SD G   C
Sbjct: 314 GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQC 371

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
             R    + + Q  + V+ ++    PK +  FS   V   EPV L     GTP P ITW 
Sbjct: 372 FVRKD--KLSAQDYVQVVLEDGT--PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWT 427

Query: 526 KDGVPIIPNPELRIH---TDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+     RI    T  G   S L+I  ++  D   Y+CTA N AG    +AR+
Sbjct: 428 LDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 485



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 68/285 (23%), Positives = 115/285 (40%), Gaps = 31/285 (10%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V+G  PI + W K+G+ +   +   I   D T +L I       +G Y C+A N A    
Sbjct: 606  VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 665

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
              ++ +V +P               P  +++P +D+    G+A+  +C   G P+PT+ W
Sbjct: 666  HQSQLIVRVP---------------PKFVVQP-RDQDGIYGKAVILNCSAEGYPVPTIVW 709

Query: 4657 Y----KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLK 4711
                  G    +P       +     +L I     ED G Y C   N  G  V+ +  L 
Sbjct: 710  KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 769

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDF--- 4767
            V  P    + P  T     +  +GQ  +       +    ++W +E  +I PE   +   
Sbjct: 770  VKIPAMITSYPNTT-----LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 824

Query: 4768 -QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             + + E   + L I  T  ED+G F+C A  + G+     +L V+
Sbjct: 825  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 869



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 46/175 (26%), Positives = 72/175 (41%), Gaps = 10/175 (5%)

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
            AN+ P I++    +    GQ +E  CK +G P P  +W K +  ++ S  FQ + T    
Sbjct: 207  ANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG--- 263

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
             L I    P D G Y C   N  G   V  +L V QP +A   P     R +    G   
Sbjct: 264  -LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISP-----RKVKSSVGSQV 317

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                 +T      + W R G ++    + + I   N+  L++ +  + D G + C
Sbjct: 318  SLSCSVTGTEDQELSWYRNGEILNPGKNVR-ITGINHENLIMDHMVKSDGGAYQC 371



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 70/290 (24%), Positives = 114/290 (39%), Gaps = 30/290 (10%)

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
            +GQ V L  K  G    D  WLK+   ++   R    ++  T  LLI    P DSG Y C
Sbjct: 224  AGQRVELPCKALGHPEPDYRWLKDNMPLELSGR---FQKTVT-GLLIENIRPSDSGSYVC 279

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
               N  G A+      V  P          KA  +P ++    K  +   G  +  SC +
Sbjct: 280  EVSNRYGTAKVIGRLYVKQP---------LKATISPRKV----KSSV---GSQVSLSCSV 323

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G     + WY+  +++ P K  +++    E  L +      D G Y+C  +    +++ 
Sbjct: 324  TGTEDQELSWYRNGEILNPGKNVRITGINHE-NLIMDHMVKSDGGAYQC--FVRKDKLSA 380

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               ++V   D    +  ++   + VV   +P      +     PTI W  +   I +   
Sbjct: 381  QDYVQVVLEDGTPKI--ISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGS 438

Query: 4767 F---QMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                QMI    N V  L I ++   D G + C A  +AG V   A++ V+
Sbjct: 439  HRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR 488



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 73/287 (25%), Positives = 111/287 (38%), Gaps = 35/287 (12%)

Query: 4439 LPL-IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            LP+ I W ++  PI  S    I      S L I  + +  +  +  +A N     +  + 
Sbjct: 610  LPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQ 669

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKV-- 4554
            L+V           VPP F +  ++ +   G+ V L+    G     + W    G  V  
Sbjct: 670  LIVR----------VPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQ 719

Query: 4555 -QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
             QP   N  ++     +LLI     +DSG Y C   N  G     A+   S+  T   P 
Sbjct: 720  FQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG-----ADVSKSMYLTVKIPA 774

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP--SKYFQM 4671
              T   N            +  +GQ  E SC   G+    V+W K D++I P  ++Y   
Sbjct: 775  MITSYPNTT----------LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 824

Query: 4672 SRTADE---YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            ++   E    TL+I     ED G + C A NS G      +L V +P
Sbjct: 825  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP 871



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 19/209 (9%)

Query: 376 QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRD 434
           Q  T + + ++ K   P F++  +    + G+     C V     P  +TW  + R I  
Sbjct: 568 QLSTSQSVHVTVKV--PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPG 625

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
                I  N     +L I+N++L  +G  TC+ARN++     Q +L V      V PKFV
Sbjct: 626 SLGVTI-DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIV-----RVPPKFV 679

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKD---GV----PIIPNPELRIHTDGGAST 547
            +    +   G+ V+LN  A G P P I W+     GV    PI  N  +++ ++G   +
Sbjct: 680 VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG---S 736

Query: 548 LDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           L I      D+ +Y C   N  G+  +++
Sbjct: 737 LLIKHVVEEDSGYYLCKVSNDVGADVSKS 765



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 50/191 (26%), Positives = 80/191 (41%), Gaps = 14/191 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T   CRV G PY  + W+ N   +   +NH+ +  E+ N  L 
Sbjct: 490 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFEN-NGTLK 546

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +++V    D G  TC           Q +L+  +   V    P F++ F       G+ V
Sbjct: 547 LSDVQKEVDEGEYTC-------NVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRV 599

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +    V    P  ITWQKDG PI  +  + I      S+L I          Y C A+N
Sbjct: 600 FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARN 659

Query: 568 VAGSTATRARL 578
            A +   +++L
Sbjct: 660 EAAAVEHQSQL 670



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 50/199 (25%), Positives = 87/199 (43%), Gaps = 15/199 (7%)

Query: 367 RSQYITDTQQRETEERIEISEKA-LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           R +Y  +T+Q  +  R+ +S+ A  AP  +     R    G+     C+  G P P+  W
Sbjct: 186 RHRYTGETRQSNSA-RLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRW 244

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             ++  +  + + +     +G   L+I N+  SDSG   C   N+ G      RL V + 
Sbjct: 245 LKDNMPL--ELSGRFQKTVTG---LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 299

Query: 486 -EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            +  ++P+ V+  S++    G  V L+    GT    ++W ++G  + P   +RI T   
Sbjct: 300 LKATISPRKVK--SSV----GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI-TGIN 352

Query: 545 ASTLDIPRAKASDAAWYQC 563
              L +     SD   YQC
Sbjct: 353 HENLIMDHMVKSDGGAYQC 371



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 68/252 (26%), Positives = 95/252 (37%), Gaps = 35/252 (13%)

Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
            I   E   +EH++Q   RV         PP F  + +       +        +G P+P 
Sbjct: 656  IARNEAAAVEHQSQLIVRV---------PPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT 706

Query: 4442 IKWYRENFPIKNSPDFQ-------IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            I W          P FQ       I   S  S+LI + V  EDS  +     N  G A  
Sbjct: 707  IVWKFSKGA--GVPQFQPIALNGRIQVLSNGSLLI-KHVVEEDSGYYLCKVSNDVG-ADV 762

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            S ++ +  K        +P   T        T GQ   +     G KPI V W K  + +
Sbjct: 763  SKSMYLTVK--------IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRII 814

Query: 4555 QPD-----IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             P+     +  K + E+   TL IL    +DSG + C AINS GE R   +  V  P   
Sbjct: 815  NPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP--P 872

Query: 4610 DKPKPQTKAANA 4621
            D P+ + K   A
Sbjct: 873  DPPEIEIKDVKA 884



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 64/322 (19%), Positives = 110/322 (34%), Gaps = 24/322 (7%)

Query: 45  TRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVS 104
           TR   T      +   +    P   +P I +  F + +   G   +   K  G+P P   
Sbjct: 185 TRHRYTGETRQSNSARLFVSDPANSAPSILDG-FDHRKAMAGQRVELPCKALGHPEPDYR 243

Query: 105 WTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
           W +   PL    + S R+ +      LLI+ I P D G Y C   N+YG A      +  
Sbjct: 244 WLKDNMPL----ELSGRFQKTV--TGLLIENIRPSDSGSYVCEVSNRYGTA------KVI 291

Query: 165 GXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVD 224
           G              R V  +V  +   +   T  + ++     Y NG   +   + ++ 
Sbjct: 292 GRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS--WYRNGEILNPGKNVRIT 349

Query: 225 TFEYRLL---REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGA 281
              +  L     V       + +V +  +     +   L   +P KI        +    
Sbjct: 350 GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP-KIISAFSEKVVSPAE 408

Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI---ITTHNHTT--LRVRNTQKSDSGHY 336
                  + G P P +TW  +   ++    H I   IT+  +    L + ++Q  D G Y
Sbjct: 409 PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVY 468

Query: 337 TLLAENPNGCIVTSGYLAVESP 358
              A N  G ++    + V  P
Sbjct: 469 RCTANNSAGVVLYQARINVRGP 490



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 13/193 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-IRDDYNHKILVNESGNHAL 450
           P  V+V +D+    G +  F C +       +T    ++  +      + L+  +G  AL
Sbjct: 111 PYTVRV-EDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTG--AL 167

Query: 451 MITNVTLSDSGV-VTCVARNK-SGET--AFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            I +V   D      C+ R++ +GET  +   RL V +     AP  ++ F       G+
Sbjct: 168 YIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANS-APSILDGFDHRKAMAGQ 226

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            V L  +A+G P P   W KD +P+    EL        + L I   + SD+  Y C   
Sbjct: 227 RVELPCKALGHPEPDYRWLKDNMPL----ELSGRFQKTVTGLLIENIRPSDSGSYVCEVS 282

Query: 567 NVAGSTATRARLY 579
           N  G+     RLY
Sbjct: 283 NRYGTAKVIGRLY 295



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 4/93 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P+K++TA+ G   +   R+  +G P   I+W KN   +  + R  +    G + L
Sbjct: 490 PASIRPMKNITAIAGRDTYIHCRV--IGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 547

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             +   + D GEYTC  +    ++ +++V HVT
Sbjct: 548 SDVQKEV-DEGEYTCNVLVQPQLSTSQSV-HVT 578



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/108 (30%), Positives = 47/108 (43%), Gaps = 6/108 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW-YRNGKLLPSGHRYRT--- 3880
            IV  PPKF+ Q +       + V   C  E    P   I W +  G  +P          
Sbjct: 671  IVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT--IVWKFSKGAGVPQFQPIALNGR 728

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +  +   SL I +V  EDSG Y+C+  ND G D +K+     K+P +I
Sbjct: 729  IQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMI 776



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 63/281 (22%), Positives = 105/281 (37%), Gaps = 26/281 (9%)

Query: 95  LRGNPTPVVSWTRKKAPLVE--CNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQ 151
           ++G P P ++WT    P+++   ++ S     +   VS L I      D G Y CTA N 
Sbjct: 416 VKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 475

Query: 152 YGEAICSVYIQPEGXXXXX-----XXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR--QT 204
            G  +    I   G                  Y H    + +  Y  + Y          
Sbjct: 476 AGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHC-RVIGYPYYSIKWYKNSNLLPFNH 534

Query: 205 QKVAY-TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
           ++VA+  NGT   S    +VD  EY     V  + S ++       V ++ ++   + P 
Sbjct: 535 RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQ------SVHVTVKVPPFIQPF 588

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
             P+ +   R             V +SG+    +TW K+G+ +  S    I      ++L
Sbjct: 589 EFPRFSIGQRVFIPC--------VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSL 640

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           R+ N     +G+YT +A N    +     L V  P +  VQ
Sbjct: 641 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQ 681



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 8/120 (6%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV--- 3173
            DSG Y C+ +N  G A++S  +    K     P   T   N      GQ     CT    
Sbjct: 746  DSGYYLCKVSNDVG-ADVSKSMYLTVKI----PAMITSYPNTTLATQGQKKEMSCTAHGE 800

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+     K +   N +  R+    K V +     L I  T   DSG + C A N YGED
Sbjct: 801  KPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGED 860



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 490  APKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKD--GVPIIPNPELRIHTDGGAS 546
            AP  +  FS T+     + +VL  +AVG P+P + W KD  G P +   + R       S
Sbjct: 1270 APARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS 1329

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGS 571
             + I   KA D+ +Y C A N  GS
Sbjct: 1330 FI-IRTVKAEDSGYYSCIANNNWGS 1353



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 4/125 (3%)

Query: 243 RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
           RY GE+    S  +  S    S P I     + K   G   +   +  G+P P   W K+
Sbjct: 188 RYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKD 247

Query: 303 GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
              L  S + +   T     L + N + SDSG Y     N  G     G L V+ P ++ 
Sbjct: 248 NMPLELSGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKAT 303

Query: 363 VQDQR 367
           +  ++
Sbjct: 304 ISPRK 308



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
            RG  S+    EP+   P + +T   + T    + +   C+     DP   ++W ++    
Sbjct: 1255 RGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVG--DPSPAVKWMKDSNGT 1312

Query: 3873 PSGHRY---RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
            PS       R+++  G  S  I  V AEDSG Y C A N++G D     +  +  PD
Sbjct: 1313 PSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPD 1367



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            +G P+    WL++ +P+E S R           L ++ + P DSG+Y C   N  G A  
Sbjct: 235  LGHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTAKV 290

Query: 1797 SSTLFVQ 1803
               L+V+
Sbjct: 291  IGRLYVK 297



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/141 (21%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W  +   +E S R +     G+++  I   + +DSG+Y C  +N++G A++  +L     
Sbjct: 244  WLKDNMPLELSGRFQKTVT-GLLIENI---RPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 299

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             K      T   + ++    G      C+V   +  D ++ WY NG+ +     ++ ++ 
Sbjct: 300  LKA-----TISPRKVKS-SVGSQVSLSCSVTGTE--DQELSWYRNGEILNPGKNVR-ITG 350

Query: 3204 FGFVVLDIAYTQNHDSGEYVC 3224
                 L + +    D G Y C
Sbjct: 351  INHENLIMDHMVKSDGGAYQC 371



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 43/190 (22%), Positives = 73/190 (38%), Gaps = 18/190 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL---VNESGNH 448
           P+FV   +D+D   GK    +C   G P P + W  +       +    L   +    N 
Sbjct: 676 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG 735

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEP 507
           +L+I +V   DSG   C   N  G    +     ++      P  +  + +T    +G+ 
Sbjct: 736 SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVK-----IPAMITSYPNTTLATQGQK 790

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT-------DGGASTLDIPRAKASDAAW 560
             ++  A G     + W+K+    I NPE+  +        +   STL I      D+ +
Sbjct: 791 KEMSCTAHGEKPIIVRWEKE--DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 848

Query: 561 YQCTAQNVAG 570
           + C A N  G
Sbjct: 849 FSCHAINSYG 858



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYV-ALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            GD  + + W KDGRP+  S  + T  N  +  +L I ++++   G+YTC A N       
Sbjct: 608  GDLPITITWQKDGRPIPGSLGV-TIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEH 666

Query: 996  SANLTIVTKKDIIAESQHPGGL 1017
             + L +      + + +   G+
Sbjct: 667  QSQLIVRVPPKFVVQPRDQDGI 688



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   +P++NI  I  G+  +  CR+I  G P   ++W++N  L+  + R     + G  +
Sbjct: 490  PASIRPMKNITAIA-GRDTYIHCRVI--GYPYYSIKWYKNSNLLPFNHRQVAFENNG--T 544

Query: 2436 MTISHVRDE-DEGVYMC 2451
            + +S V+ E DEG Y C
Sbjct: 545  LKLSDVQKEVDEGEYTC 561



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 5/67 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRI---RTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            GD S  ++W  +     +   I   R++++ G  ++  +  K  DSG YSC A N WG  
Sbjct: 1297 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV--KAEDSGYYSCIANNNWGSD 1354

Query: 3133 EISVKLE 3139
            EI + L+
Sbjct: 1355 EIILNLQ 1361



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 7/104 (6%)

Query: 2623 EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG 2682
            E   +    +FV      AP        + K + GQ V L  +     +P+ +  W K+ 
Sbjct: 192  ETRQSNSARLFVSDPANSAPSILDGF-DHRKAMAGQRVELPCKALGHPEPDYR--WLKDN 248

Query: 2683 VTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            + L    R + T    +  L I ++R  DSG Y C+ +N  G A
Sbjct: 249  MPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTA 288



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  I  +K+ T          CRV     P   I+WY+N  LLP  HR     + G + L
Sbjct: 490  PASIRPMKNITAIAGRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 547

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              +     D GEY C  +       +++     K+P  I   + PR
Sbjct: 548  SDVQKEV-DEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR 592



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSG 3875
            +D  K   +    P  IT   + T+  ++G + E       +  + + W +  +++ P  
Sbjct: 760  ADVSKSMYLTVKIPAMITSYPNTTLA-TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEM 818

Query: 3876 HRY----RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             RY    + V +    +L IL    EDSG + C A+N +GED     ++ ++ PD
Sbjct: 819  ARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD 873



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 13/134 (9%)

Query: 3094 SHRI-RTVYAFGMVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPR 3150
            SHRI + + + G VV  L I  ++  D G Y C A N  G      ++        + P 
Sbjct: 438  SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV------RGPA 491

Query: 3151 FTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLD 3210
                ++NI  +  G+  +  C V+    P   I+WY N   +  + R     + G + L 
Sbjct: 492  SIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKLS 548

Query: 3211 IAYTQNHDSGEYVC 3224
                +  D GEY C
Sbjct: 549  -DVQKEVDEGEYTC 561



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 10/100 (10%)

Query: 3683 EEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRP--F 3738
            E IT+E     P R  +     +  P    +   C+   VGDP+  + W    NG P   
Sbjct: 1260 EIITVEPLAKAPARI-LTFSGTVTTPWMKDIVLPCKA--VGDPSPAVKWMKDSNGTPSLV 1316

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
                R    ++  FI   I  + A D+G Y+C A N WGS
Sbjct: 1317 TIDGRRSIFSNGSFI---IRTVKAEDSGYYSCIANNNWGS 1353



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKD--GRP--VEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD +  V+W+KD  G P  V    R + F N  ++  T+K+    D+G+Y+C A N  G
Sbjct: 1296 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKA---EDSGYYSCIANNNWG 1352

Query: 992  QATTSANLTIVTKKD 1006
                  NL +    D
Sbjct: 1353 SDEIILNLQVQVPPD 1367



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 4436 GEPLPLIKWYREN--FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            G+P P +KW +++   P   + D +   FS  S  IIR V  EDS  ++ +A N  G+ +
Sbjct: 1297 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF-IIRTVKAEDSGYYSCIANNNWGSDE 1355

Query: 4494 CSANLVVEEKRRQGR 4508
               NL V+    Q R
Sbjct: 1356 IILNLQVQVPPDQPR 1370



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 32/130 (24%), Positives = 48/130 (36%), Gaps = 13/130 (10%)

Query: 1543 VRSTQNEAGLEQIQVL-------EDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRA 1595
            ++  QNE GL   + +       E R        V +    AP       + +   GQR 
Sbjct: 169  IKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRV 228

Query: 1596 HFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAI 1655
                + +   +   +  W  +N PL+   RF +T       L I +  P DSG+Y C   
Sbjct: 229  ELPCKALGHPEPDYR--WLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVS 282

Query: 1656 NALGEAVTSG 1665
            N  G A   G
Sbjct: 283  NRYGTAKVIG 292



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 7/100 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKS----THDFSYVS 2832
            IS  +  V    + +   CNV+ +  PT  I W  ++ P+  G  ++     T + + VS
Sbjct: 396  ISAFSEKVVSPAEPVSLMCNVKGTPLPT--ITWTLDDDPILKGGSHRISQMITSEGNVVS 453

Query: 2833 -LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
             L+I+ +   D G+Y C A NS G       +   G  +I
Sbjct: 454  YLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI 493



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 7/99 (7%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH-RYRTSN-DFG- 1900
            P  IT     T  ++GQ     C    + +  + V W    +++     RY  S  + G 
Sbjct: 773  PAMITSYPNTTLATQGQKKEMSCTA--HGEKPIIVRWEKEDRIINPEMARYLVSTKEVGE 830

Query: 1901 --FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               + L IL    EDSG ++C AIN+ G+    I+L VQ
Sbjct: 831  EVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 869



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA----DEYTLRISEAFPEDEGDYKC 4695
            I   CK VG P P V+W K D    PS      R +      + +R  +A  ED G Y C
Sbjct: 1289 IVLPCKAVGDPSPAVKWMK-DSNGTPSLVTIDGRRSIFSNGSFIIRTVKA--EDSGYYSC 1345

Query: 4696 VAYNSAGRVTVAAKLKV-TQPDQ 4717
            +A N+ G   +   L+V   PDQ
Sbjct: 1346 IANNNWGSDEIILNLQVQVPPDQ 1368



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + P  I  +   T ++ G+  +  CR+  YP     ++WY N  +L   HR     + G 
Sbjct: 488  RGPASIRPMKNITAIA-GRDTYIHCRVIGYP--YYSIKWYKNSNLLPFNHRQVAFENNG- 543

Query: 1902 AALDILTVYGE-DSGEYTCKAI 1922
              L +  V  E D GEYTC  +
Sbjct: 544  -TLKLSDVQKEVDEGEYTCNVL 564



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 6/68 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            GQ     C+ +  G P     W ++   +E S R  KT       + I ++R  D G Y+
Sbjct: 225  GQRVELPCKAL--GHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYV 278

Query: 2451 CRASNLLG 2458
            C  SN  G
Sbjct: 279  CEVSNRYG 286



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 10/93 (10%)

Query: 663  VGDPTMKIEWLK--NG-QSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
            VGDP+  ++W+K  NG  S+       SIF  G  S  + ++  +DSG Y+C A +  G 
Sbjct: 1296 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGS 1353

Query: 720  AETKAVLHV-----TPRATIERTSQHPETLQYI 747
             E    L V      PR T+ +T+    TL ++
Sbjct: 1354 DEIILNLQVQVPPDQPRLTVSKTTSSSITLSWL 1386



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 7/80 (8%)

Query: 1471 VTDSNLKVEWFK--NGQP--VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            V D +  V+W K  NG P  VTI  R R I   G   +  +   AEDSG Y+C A N  G
Sbjct: 1296 VGDPSPAVKWMKDSNGTPSLVTIDGR-RSIFSNGSFIIRTVK--AEDSGYYSCIANNNWG 1352

Query: 1527 TDEVSCRLTCRSTTDIVRST 1546
            +DE+   L  +   D  R T
Sbjct: 1353 SDEIILNLQVQVPPDQPRLT 1372



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI-KTVSDFGFVVLDIAYTQNHDSGEY 3222
            GQ     C  +   +PD +  W  +  P+  S R  KTV+  G ++ +I   +  DSG Y
Sbjct: 225  GQRVELPCKALGHPEPDYR--WLKDNMPLELSGRFQKTVT--GLLIENI---RPSDSGSY 277

Query: 3223 VCRAYNKYG 3231
            VC   N+YG
Sbjct: 278  VCEVSNRYG 286



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 9/94 (9%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG-----QPVTIGHRFR 1494
            V + P+FV +P+  ++ I G+ V   C  E      +  ++ K       QP+ +  R +
Sbjct: 672  VRVPPKFVVQPRD-QDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQ 730

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             + +   +   +++   EDSG Y C+  N VG D
Sbjct: 731  VLSNGSLLIKHVVE---EDSGYYLCKVSNDVGAD 761



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKD  P+E S R    F      L I+++   D+G Y C   N  G A     L +
Sbjct: 244  WLKDNMPLELSGR----FQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 296



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 1/98 (1%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V  + P F  P +  R +  Q   F   ++  GD  + + W ++G PI  S  +T  +  
Sbjct: 577  VTVKVPPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNID 635

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
               +L +  ++   +G YTC A NE       S L V+
Sbjct: 636  FTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR 673



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP       + + + G  V L C+   +G       W  +  P++   RF+         
Sbjct: 210  APSILDGFDHRKAMAGQRVELPCKA--LGHPEPDYRWLKDNMPLELSGRFQKTV----TG 263

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEA 1394
            L + ++ P DSG Y C+ +N+ G A
Sbjct: 264  LLIENIRPSDSGSYVCEVSNRYGTA 288



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 35/171 (20%), Positives = 70/171 (40%), Gaps = 14/171 (8%)

Query: 3072 LIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            ++ +GD  + I W  +G+ I  S  +          L I       +G Y+C A N+   
Sbjct: 604  VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 663

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-- 3189
             E   +L          P+F    ++ +G+  G++    C+      P +  ++      
Sbjct: 664  VEHQSQLIV-----RVPPKFVVQPRDQDGIY-GKAVILNCSAEGYPVPTIVWKFSKGAGV 717

Query: 3190 ---QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
               QP+  + RI+ +S+   ++  +      DSG Y+C+  N  G D +++
Sbjct: 718  PQFQPIALNGRIQVLSNGSLLIKHVV---EEDSGYYLCKVSNDVGADVSKS 765



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P  I  ++++T +  G+  +   R++    P   ++W+ N   LP  HR   F + G + 
Sbjct: 490  PASIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLK 546

Query: 3342 LDILYCYEENSGEYEC 3357
            L  +   E + GEY C
Sbjct: 547  LSDVQ-KEVDEGEYTC 561



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
           T + P FI+P +       G+       +    D  + + W KDGRPI  S  +T I N 
Sbjct: 578 TVKVPPFIQPFE-FPRFSIGQRVFIPCVVVS-GDLPITITWQKDGRPIPGSLGVT-IDNI 634

Query: 826 GYV-SLNIMHLRAEDAGSYTVRAVNK 850
            +  SL I +L     G+YT  A N+
Sbjct: 635 DFTSSLRISNLSLMHNGNYTCIARNE 660



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 5/106 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS- 695
           P FI P +      G ++ F   +   GD  + I W K+G+ I  S   T I    + S 
Sbjct: 582 PPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVT-IDNIDFTSS 639

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAE--TKAVLHVTPRATIERTSQ 739
           L + +L++  +G YTC A +     E  ++ ++ V P+  ++   Q
Sbjct: 640 LRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQ 685



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 13/92 (14%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW-FHNG------RPFATGSRVHT 3746
            PP+F V+ +D  D   G  V  +C  E  G P   I W F  G      +P A   R+  
Sbjct: 675  PPKFVVQPRDQ-DGIYGKAVILNCSAE--GYPVPTIVWKFSKGAGVPQFQPIALNGRIQV 731

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            L++   +   I ++   D+G Y C+ +N  G+
Sbjct: 732  LSNGSLL---IKHVVEEDSGYYLCKVSNDVGA 760


>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhesion
            molecule isoform CHD2-42 precursor variant protein.
          Length = 2023

 Score =  112 bits (269), Expect = 3e-23
 Identities = 97/383 (25%), Positives = 160/383 (41%), Gaps = 43/383 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P  +W ++N P++ S  FQ     T + L+I  +   DS  +     NR GTAK  
Sbjct: 261  GHPEPDYRWLKDNMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVI 316

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              L V++          P   T++ + V  + G  V L   VTGT+  ++ W +NG+ + 
Sbjct: 317  GRLYVKQ----------PLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILN 366

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P  +N  +       L++      D G Y+C        A+   + V+            
Sbjct: 367  PG-KNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLE----------- 414

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKY--FQMS 4672
                +  P+II    +K+V+  + +   C + G PLPT+ W    D ++K   +   QM 
Sbjct: 415  ----DGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMI 470

Query: 4673 RTADEYT--LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
             +       L IS +   D G Y+C A NSAG V   A++ V  P       ++ P+++I
Sbjct: 471  TSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGP------ASIRPMKNI 524

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
                G+      ++      +I+W +   L+P     Q+  E N  + L     E D G 
Sbjct: 525  TAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGE 583

Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813
            +TC       Q+ TS  + V  K
Sbjct: 584  YTCNVLVQP-QLSTSQSVHVTVK 605



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 94/382 (24%), Positives = 145/382 (37%), Gaps = 34/382 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G PLP I W  ++ PI      +I    T    ++  + +  S V        GG  +C+
Sbjct: 443  GTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQV------RDGGVYRCT 496

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            AN        Q R  +  P+     +N+   +G+   +  +V G     + W KN   + 
Sbjct: 497  ANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLP 556

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
             + R    E +GT  L  ++    D G+Y C  +            V    +T       
Sbjct: 557  FNHRQVAFENNGTLKLSDVQK-EVDEGEYTCNVL------------VQPQLSTSQSVHVT 603

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRT 4674
             K     P  I+P +    + GQ +   C +V   LP T+ W K  + I  S    +   
Sbjct: 604  VKV----PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI 659

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
                +LRIS       G+Y C+A N A  V   ++L V  P +    P     RD     
Sbjct: 660  DFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP-----RDQDGIY 714

Query: 4735 GQPAQFKTQITSKIKPTIQW-LREGALIPETPDFQM---IHEGNNAVLLIGNTYEEDTGT 4790
            G+             PTI W   +GA +P+     +   I   +N  LLI +  EED+G 
Sbjct: 715  GKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGY 774

Query: 4791 FTCRATTAAG-QVETSAKLVVK 4811
            + C+ +   G  V  S  L VK
Sbjct: 775  YLCKVSNDVGADVSKSMYLTVK 796



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 79/336 (23%), Positives = 133/336 (39%), Gaps = 49/336 (14%)

Query: 235 SFRESITKRYVGESDVQIST-EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293
           + R S +  YV E   +  T ++   L    P K    PR  K   G+       ++G  
Sbjct: 293 NIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTE 352

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
              ++W++NG+ ++N  K+  IT  NH  L + +  KSD G Y         C V    L
Sbjct: 353 DQELSWYRNGE-ILNPGKNVRITGINHENLIMDHMVKSDGGAYQ--------CFVRKDKL 403

Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
           + +   +  ++D   + I+             SEK ++P              +     C
Sbjct: 404 SAQDYVQVVLEDGTPKIIS-----------AFSEKVVSP-------------AEPVSLMC 439

Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKI--LVNESGN--HALMITNVTLSDSGVVTCVARN 469
            V G P P +TW ++D  I    +H+I  ++   GN    L I++  + D GV  C A N
Sbjct: 440 NVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANN 499

Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
            +G   +Q R+N      V  P  +     +    G    ++ R +G P   I W K+  
Sbjct: 500 SAGVVLYQARIN------VRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNS- 552

Query: 530 PIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            ++P  + ++    +G     D+   K  D   Y C
Sbjct: 553 NLLPFNHRQVAFENNGTLKLSDV--QKEVDEGEYTC 586



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 55/178 (30%), Positives = 78/178 (43%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C VTG    E++W+ N   +    N +I      N  L++ ++  SD G   C
Sbjct: 339 GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN--LIMDHMVKSDGGAYQC 396

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
             R    + + Q  + V+ ++    PK +  FS   V   EPV L     GTP P ITW 
Sbjct: 397 FVRKD--KLSAQDYVQVVLEDGT--PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWT 452

Query: 526 KDGVPIIPNPELRIH---TDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+     RI    T  G   S L+I  ++  D   Y+CTA N AG    +AR+
Sbjct: 453 LDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 510



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 68/285 (23%), Positives = 115/285 (40%), Gaps = 31/285 (10%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V+G  PI + W K+G+ +   +   I   D T +L I       +G Y C+A N A    
Sbjct: 631  VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 690

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
              ++ +V +P               P  +++P +D+    G+A+  +C   G P+PT+ W
Sbjct: 691  HQSQLIVRVP---------------PKFVVQP-RDQDGIYGKAVILNCSAEGYPVPTIVW 734

Query: 4657 Y----KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLK 4711
                  G    +P       +     +L I     ED G Y C   N  G  V+ +  L 
Sbjct: 735  KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 794

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PETPDF--- 4767
            V  P    + P  T     +  +GQ  +       +    ++W +E  +I PE   +   
Sbjct: 795  VKIPAMITSYPNTT-----LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 849

Query: 4768 -QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             + + E   + L I  T  ED+G F+C A  + G+     +L V+
Sbjct: 850  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 894



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 46/175 (26%), Positives = 73/175 (41%), Gaps = 10/175 (5%)

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
            AN+ P I++  + +    GQ +E  CK +G P P  +W K +  ++ S  FQ + T    
Sbjct: 232  ANSAPSILDGFEHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG--- 288

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
             L I    P D G Y C   N  G   V  +L V QP +A   P     R +    G   
Sbjct: 289  -LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISP-----RKVKSSVGSQV 342

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                 +T      + W R G ++    + + I   N+  L++ +  + D G + C
Sbjct: 343  SLSCSVTGTEDQELSWYRNGEILNPGKNVR-ITGINHENLIMDHMVKSDGGAYQC 396



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 43/382 (11%)

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAV-FAAVAENR--GGTAKC- 4494
            + ++ W ++   + +   F I   ++   L I+ V  ED    +  +  +R  G T +  
Sbjct: 166  ITVVSWEKDTVSLVSGSRFLI---TSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSN 222

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            SA L V +           PS     ++    +GQ V L  K  G    D  WLK+   +
Sbjct: 223  SARLFVSDPANSA------PSILDGFEHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPL 276

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            +   R    ++  T  LLI    P DSG Y C   N  G A+      V  P        
Sbjct: 277  ELSGR---FQKTVT-GLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP-------- 324

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
              KA  +P ++    K  +   G  +  SC + G     + WY+  +++ P K  +++  
Sbjct: 325  -LKATISPRKV----KSSV---GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGI 376

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
              E  L +      D G Y+C  +    +++    ++V   D    +  ++   + VV  
Sbjct: 377  NHE-NLIMDHMVKSDGGAYQC--FVRKDKLSAQDYVQVVLEDGTPKI--ISAFSEKVVSP 431

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDF---QMIHEGNNAV--LLIGNTYEEDTG 4789
             +P      +     PTI W  +   I +       QMI    N V  L I ++   D G
Sbjct: 432  AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGG 491

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
             + C A  +AG V   A++ V+
Sbjct: 492  VYRCTANNSAGVVLYQARINVR 513



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 73/287 (25%), Positives = 111/287 (38%), Gaps = 35/287 (12%)

Query: 4439 LPL-IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            LP+ I W ++  PI  S    I      S L I  + +  +  +  +A N     +  + 
Sbjct: 635  LPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQ 694

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKV-- 4554
            L+V           VPP F +  ++ +   G+ V L+    G     + W    G  V  
Sbjct: 695  LIVR----------VPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQ 744

Query: 4555 -QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
             QP   N  ++     +LLI     +DSG Y C   N  G     A+   S+  T   P 
Sbjct: 745  FQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG-----ADVSKSMYLTVKIPA 799

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP--SKYFQM 4671
              T   N            +  +GQ  E SC   G+    V+W K D++I P  ++Y   
Sbjct: 800  MITSYPNTT----------LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVS 849

Query: 4672 SRTADE---YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            ++   E    TL+I     ED G + C A NS G      +L V +P
Sbjct: 850  TKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP 896



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 19/209 (9%)

Query: 376 QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRD 434
           Q  T + + ++ K   P F++  +    + G+     C V     P  +TW  + R I  
Sbjct: 593 QLSTSQSVHVTVKV--PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPG 650

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
                I  N     +L I+N++L  +G  TC+ARN++     Q +L V      V PKFV
Sbjct: 651 SLGVTI-DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIV-----RVPPKFV 704

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKD---GV----PIIPNPELRIHTDGGAST 547
            +    +   G+ V+LN  A G P P I W+     GV    PI  N  +++ ++G   +
Sbjct: 705 VQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG---S 761

Query: 548 LDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           L I      D+ +Y C   N  G+  +++
Sbjct: 762 LLIKHVVEEDSGYYLCKVSNDVGADVSKS 790



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 50/199 (25%), Positives = 88/199 (44%), Gaps = 15/199 (7%)

Query: 367 RSQYITDTQQRETEERIEISEKA-LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           R +Y  +T+Q  +  R+ +S+ A  AP  +   + R    G+     C+  G P P+  W
Sbjct: 211 RHRYTGETRQSNSA-RLFVSDPANSAPSILDGFEHRKAMAGQRVELPCKALGHPEPDYRW 269

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
             ++  +  + + +     +G   L+I N+  SDSG   C   N+ G      RL V + 
Sbjct: 270 LKDNMPL--ELSGRFQKTVTG---LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 324

Query: 486 -EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            +  ++P+ V+  S++    G  V L+    GT    ++W ++G  + P   +RI T   
Sbjct: 325 LKATISPRKVK--SSV----GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI-TGIN 377

Query: 545 ASTLDIPRAKASDAAWYQC 563
              L +     SD   YQC
Sbjct: 378 HENLIMDHMVKSDGGAYQC 396



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 50/191 (26%), Positives = 80/191 (41%), Gaps = 14/191 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T   CRV G PY  + W+ N   +   +NH+ +  E+ N  L 
Sbjct: 515 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL--PFNHRQVAFEN-NGTLK 571

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +++V    D G  TC           Q +L+  +   V    P F++ F       G+ V
Sbjct: 572 LSDVQKEVDEGEYTC-------NVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRV 624

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +    V    P  ITWQKDG PI  +  + I      S+L I          Y C A+N
Sbjct: 625 FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARN 684

Query: 568 VAGSTATRARL 578
            A +   +++L
Sbjct: 685 EAAAVEHQSQL 695



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 68/252 (26%), Positives = 95/252 (37%), Gaps = 35/252 (13%)

Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
            I   E   +EH++Q   RV         PP F  + +       +        +G P+P 
Sbjct: 681  IARNEAAAVEHQSQLIVRV---------PPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT 731

Query: 4442 IKWYRENFPIKNSPDFQ-------IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            I W          P FQ       I   S  S+LI + V  EDS  +     N  G A  
Sbjct: 732  IVWKFSKGA--GVPQFQPIALNGRIQVLSNGSLLI-KHVVEEDSGYYLCKVSNDVG-ADV 787

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            S ++ +  K        +P   T        T GQ   +     G KPI V W K  + +
Sbjct: 788  SKSMYLTVK--------IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRII 839

Query: 4555 QPD-----IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             P+     +  K + E+   TL IL    +DSG + C AINS GE R   +  V  P   
Sbjct: 840  NPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEP--P 897

Query: 4610 DKPKPQTKAANA 4621
            D P+ + K   A
Sbjct: 898  DPPEIEIKDVKA 909



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 64/322 (19%), Positives = 111/322 (34%), Gaps = 24/322 (7%)

Query: 45  TRQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVS 104
           TR   T      +   +    P   +P I +  F++ +   G   +   K  G+P P   
Sbjct: 210 TRHRYTGETRQSNSARLFVSDPANSAPSILDG-FEHRKAMAGQRVELPCKALGHPEPDYR 268

Query: 105 WTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
           W +   PL    + S R+ +      LLI+ I P D G Y C   N+YG A      +  
Sbjct: 269 WLKDNMPL----ELSGRFQKTV--TGLLIENIRPSDSGSYVCEVSNRYGTA------KVI 316

Query: 165 GXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVD 224
           G              R V  +V  +   +   T  + ++     Y NG   +   + ++ 
Sbjct: 317 GRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELS--WYRNGEILNPGKNVRIT 374

Query: 225 TFEYRLL---REVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGA 281
              +  L     V       + +V +  +     +   L   +P KI        +    
Sbjct: 375 GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP-KIISAFSEKVVSPAE 433

Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI---ITTHNHTT--LRVRNTQKSDSGHY 336
                  + G P P +TW  +   ++    H I   IT+  +    L + ++Q  D G Y
Sbjct: 434 PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVY 493

Query: 337 TLLAENPNGCIVTSGYLAVESP 358
              A N  G ++    + V  P
Sbjct: 494 RCTANNSAGVVLYQARINVRGP 515



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 13/193 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-IRDDYNHKILVNESGNHAL 450
           P  V+V +D+    G +  F C +       +T    ++  +      + L+  +G  AL
Sbjct: 136 PYTVRV-EDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTG--AL 192

Query: 451 MITNVTLSDSGV-VTCVARNK-SGET--AFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            I +V   D      C+ R++ +GET  +   RL V +     AP  ++ F       G+
Sbjct: 193 YIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANS-APSILDGFEHRKAMAGQ 251

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            V L  +A+G P P   W KD +P+    EL        + L I   + SD+  Y C   
Sbjct: 252 RVELPCKALGHPEPDYRWLKDNMPL----ELSGRFQKTVTGLLIENIRPSDSGSYVCEVS 307

Query: 567 NVAGSTATRARLY 579
           N  G+     RLY
Sbjct: 308 NRYGTAKVIGRLY 320



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 4/93 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P+K++TA+ G   +   R+  +G P   I+W KN   +  + R  +    G + L
Sbjct: 515 PASIRPMKNITAIAGRDTYIHCRV--IGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 572

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             +   + D GEYTC  +    ++ +++V HVT
Sbjct: 573 SDVQKEV-DEGEYTCNVLVQPQLSTSQSV-HVT 603



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 33/108 (30%), Positives = 47/108 (43%), Gaps = 6/108 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW-YRNGKLLPSGHRYRT--- 3880
            IV  PPKF+ Q +       + V   C  E    P   I W +  G  +P          
Sbjct: 696  IVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT--IVWKFSKGAGVPQFQPIALNGR 753

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +  +   SL I +V  EDSG Y+C+  ND G D +K+     K+P +I
Sbjct: 754  IQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMI 801



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 4/125 (3%)

Query: 243 RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
           RY GE+    S  +  S    S P I     + K   G   +   +  G+P P   W K+
Sbjct: 213 RYTGETRQSNSARLFVSDPANSAPSILDGFEHRKAMAGQRVELPCKALGHPEPDYRWLKD 272

Query: 303 GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
              L  S + +       T L + N + SDSG Y     N  G     G L V+ P ++ 
Sbjct: 273 NMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKAT 328

Query: 363 VQDQR 367
           +  ++
Sbjct: 329 ISPRK 333



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 63/281 (22%), Positives = 105/281 (37%), Gaps = 26/281 (9%)

Query: 95  LRGNPTPVVSWTRKKAPLVE--CNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQ 151
           ++G P P ++WT    P+++   ++ S     +   VS L I      D G Y CTA N 
Sbjct: 441 VKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 500

Query: 152 YGEAICSVYIQPEGXXXXX-----XXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR--QT 204
            G  +    I   G                  Y H    + +  Y  + Y          
Sbjct: 501 AGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHC-RVIGYPYYSIKWYKNSNLLPFNH 559

Query: 205 QKVAY-TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
           ++VA+  NGT   S    +VD  EY     V  + S ++       V ++ ++   + P 
Sbjct: 560 RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQ------SVHVTVKVPPFIQPF 613

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
             P+ +   R             V +SG+    +TW K+G+ +  S    I      ++L
Sbjct: 614 EFPRFSIGQRVFIPC--------VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSL 665

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           R+ N     +G+YT +A N    +     L V  P +  VQ
Sbjct: 666 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQ 706



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 8/120 (6%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV--- 3173
            DSG Y C+ +N  G A++S  +    K     P   T   N      GQ     CT    
Sbjct: 771  DSGYYLCKVSNDVG-ADVSKSMYLTVKI----PAMITSYPNTTLATQGQKKEMSCTAHGE 825

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             P+     K +   N +  R+    K V +     L I  T   DSG + C A N YGED
Sbjct: 826  KPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGED 885



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 490  APKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKD--GVPIIPNPELRIHTDGGAS 546
            AP  +  FS T+     + +VL  +AVG P+P + W KD  G P +   + R       S
Sbjct: 1295 APARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS 1354

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGS 571
             + I   KA D+ +Y C A N  GS
Sbjct: 1355 FI-IRTVKAEDSGYYSCIANNNWGS 1378



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
            RG  S+    EP+   P + +T   + T    + +   C+     DP   ++W ++    
Sbjct: 1280 RGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVG--DPSPAVKWMKDSNGT 1337

Query: 3873 PSGHRY---RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
            PS       R+++  G  S  I  V AEDSG Y C A N++G D     +  +  PD
Sbjct: 1338 PSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPD 1392



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            +G P+    WL++ +P+E S R           L ++ + P DSG+Y C   N  G A  
Sbjct: 260  LGHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTAKV 315

Query: 1797 SSTLFVQ 1803
               L+V+
Sbjct: 316  IGRLYVK 322



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/141 (21%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W  +   +E S R +     G+++  I   + +DSG+Y C  +N++G A++  +L     
Sbjct: 269  WLKDNMPLELSGRFQKTVT-GLLIENI---RPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 324

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
             K      T   + ++    G      C+V   +  D ++ WY NG+ +     ++ ++ 
Sbjct: 325  LKA-----TISPRKVKS-SVGSQVSLSCSVTGTE--DQELSWYRNGEILNPGKNVR-ITG 375

Query: 3204 FGFVVLDIAYTQNHDSGEYVC 3224
                 L + +    D G Y C
Sbjct: 376  INHENLIMDHMVKSDGGAYQC 396



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 43/190 (22%), Positives = 73/190 (38%), Gaps = 18/190 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL---VNESGNH 448
           P+FV   +D+D   GK    +C   G P P + W  +       +    L   +    N 
Sbjct: 701 PKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG 760

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEP 507
           +L+I +V   DSG   C   N  G    +     ++      P  +  + +T    +G+ 
Sbjct: 761 SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVK-----IPAMITSYPNTTLATQGQK 815

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT-------DGGASTLDIPRAKASDAAW 560
             ++  A G     + W+K+    I NPE+  +        +   STL I      D+ +
Sbjct: 816 KEMSCTAHGEKPIIVRWEKE--DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 873

Query: 561 YQCTAQNVAG 570
           + C A N  G
Sbjct: 874 FSCHAINSYG 883



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYV-ALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            GD  + + W KDGRP+  S  + T  N  +  +L I ++++   G+YTC A N       
Sbjct: 633  GDLPITITWQKDGRPIPGSLGV-TIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEH 691

Query: 996  SANLTIVTKKDIIAESQHPGGL 1017
             + L +      + + +   G+
Sbjct: 692  QSQLIVRVPPKFVVQPRDQDGI 713



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 7/104 (6%)

Query: 2623 EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG 2682
            E   +    +FV      AP      + + K + GQ V L  +     +P+ +  W K+ 
Sbjct: 217  ETRQSNSARLFVSDPANSAPSILDGFE-HRKAMAGQRVELPCKALGHPEPDYR--WLKDN 273

Query: 2683 VTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            + L    R + T    +  L I ++R  DSG Y C+ +N  G A
Sbjct: 274  MPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVSNRYGTA 313



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   +P++NI  I  G+  +  CR+I  G P   ++W++N  L+  + R     + G  +
Sbjct: 515  PASIRPMKNITAIA-GRDTYIHCRVI--GYPYYSIKWYKNSNLLPFNHRQVAFENNG--T 569

Query: 2436 MTISHVRDE-DEGVYMC 2451
            + +S V+ E DEG Y C
Sbjct: 570  LKLSDVQKEVDEGEYTC 586



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 5/67 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRI---RTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            GD S  ++W  +     +   I   R++++ G  ++  +  K  DSG YSC A N WG  
Sbjct: 1322 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTV--KAEDSGYYSCIANNNWGSD 1379

Query: 3133 EISVKLE 3139
            EI + L+
Sbjct: 1380 EIILNLQ 1386



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  I  +K+ T          CRV     P   I+WY+N  LLP  HR     + G + L
Sbjct: 515  PASIRPMKNITAIAGRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKL 572

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              +     D GEY C  +       +++     K+P  I   + PR
Sbjct: 573  SDVQKEV-DEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR 617



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/130 (24%), Positives = 49/130 (37%), Gaps = 13/130 (10%)

Query: 1543 VRSTQNEAGLEQIQVL-------EDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRA 1595
            ++  QNE GL   + +       E R        V +    AP      ++ +   GQR 
Sbjct: 194  IKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFEHRKAMAGQRV 253

Query: 1596 HFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAI 1655
                + +   +   +  W  +N PL+   RF +T       L I +  P DSG+Y C   
Sbjct: 254  ELPCKALGHPEPDYR--WLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYVCEVS 307

Query: 1656 NALGEAVTSG 1665
            N  G A   G
Sbjct: 308  NRYGTAKVIG 317



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSG 3875
            +D  K   +    P  IT   + T+  ++G + E       +  + + W +  +++ P  
Sbjct: 785  ADVSKSMYLTVKIPAMITSYPNTTLA-TQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEM 843

Query: 3876 HRY----RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             RY    + V +    +L IL    EDSG + C A+N +GED     ++ ++ PD
Sbjct: 844  ARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD 898



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 13/134 (9%)

Query: 3094 SHRI-RTVYAFGMVV--LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPR 3150
            SHRI + + + G VV  L I  ++  D G Y C A N  G      ++        + P 
Sbjct: 463  SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINV------RGPA 516

Query: 3151 FTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLD 3210
                ++NI  +  G+  +  C V+    P   I+WY N   +  + R     + G + L 
Sbjct: 517  SIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLKLS 573

Query: 3211 IAYTQNHDSGEYVC 3224
                +  D GEY C
Sbjct: 574  -DVQKEVDEGEYTC 586



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 10/100 (10%)

Query: 3683 EEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRP--F 3738
            E IT+E     P R  +     +  P    +   C+   VGDP+  + W    NG P   
Sbjct: 1285 EIITVEPLAKAPARI-LTFSGTVTTPWMKDIVLPCKA--VGDPSPAVKWMKDSNGTPSLV 1341

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
                R    ++  FI   I  + A D+G Y+C A N WGS
Sbjct: 1342 TIDGRRSIFSNGSFI---IRTVKAEDSGYYSCIANNNWGS 1378



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKD--GRP--VEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD +  V+W+KD  G P  V    R + F N  ++  T+K+    D+G+Y+C A N  G
Sbjct: 1321 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKA---EDSGYYSCIANNNWG 1377

Query: 992  QATTSANLTIVTKKD 1006
                  NL +    D
Sbjct: 1378 SDEIILNLQVQVPPD 1392



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 4436 GEPLPLIKWYREN--FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            G+P P +KW +++   P   + D +   FS  S  IIR V  EDS  ++ +A N  G+ +
Sbjct: 1322 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF-IIRTVKAEDSGYYSCIANNNWGSDE 1380

Query: 4494 CSANLVVEEKRRQGR 4508
               NL V+    Q R
Sbjct: 1381 IILNLQVQVPPDQPR 1395



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 7/100 (7%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKS----THDFSYVS 2832
            IS  +  V    + +   CNV+ +  PT  I W  ++ P+  G  ++     T + + VS
Sbjct: 421  ISAFSEKVVSPAEPVSLMCNVKGTPLPT--ITWTLDDDPILKGGSHRISQMITSEGNVVS 478

Query: 2833 -LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
             L+I+ +   D G+Y C A NS G       +   G  +I
Sbjct: 479  YLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI 518



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 7/99 (7%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH-RYRTSN-DFG- 1900
            P  IT     T  ++GQ     C    + +  + V W    +++     RY  S  + G 
Sbjct: 798  PAMITSYPNTTLATQGQKKEMSCTA--HGEKPIIVRWEKEDRIINPEMARYLVSTKEVGE 855

Query: 1901 --FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               + L IL    EDSG ++C AIN+ G+    I+L VQ
Sbjct: 856  EVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 894



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA----DEYTLRISEAFPEDEGDYKC 4695
            I   CK VG P P V+W K D    PS      R +      + +R  +A  ED G Y C
Sbjct: 1314 IVLPCKAVGDPSPAVKWMK-DSNGTPSLVTIDGRRSIFSNGSFIIRTVKA--EDSGYYSC 1370

Query: 4696 VAYNSAGRVTVAAKLKV-TQPDQ 4717
            +A N+ G   +   L+V   PDQ
Sbjct: 1371 IANNNWGSDEIILNLQVQVPPDQ 1393



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + P  I  +   T ++ G+  +  CR+  YP     ++WY N  +L   HR     + G 
Sbjct: 513  RGPASIRPMKNITAIA-GRDTYIHCRVIGYP--YYSIKWYKNSNLLPFNHRQVAFENNG- 568

Query: 1902 AALDILTVYGE-DSGEYTCKAI 1922
              L +  V  E D GEYTC  +
Sbjct: 569  -TLKLSDVQKEVDEGEYTCNVL 589



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 6/68 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            GQ     C+ +  G P     W ++   +E S R  KT       + I ++R  D G Y+
Sbjct: 250  GQRVELPCKAL--GHPEPDYRWLKDNMPLELSGRFQKT----VTGLLIENIRPSDSGSYV 303

Query: 2451 CRASNLLG 2458
            C  SN  G
Sbjct: 304  CEVSNRYG 311



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 10/93 (10%)

Query: 663  VGDPTMKIEWLK--NG-QSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
            VGDP+  ++W+K  NG  S+       SIF  G  S  + ++  +DSG Y+C A +  G 
Sbjct: 1321 VGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG--SFIIRTVKAEDSGYYSCIANNNWGS 1378

Query: 720  AETKAVLHV-----TPRATIERTSQHPETLQYI 747
             E    L V      PR T+ +T+    TL ++
Sbjct: 1379 DEIILNLQVQVPPDQPRLTVSKTTSSSITLSWL 1411



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 7/80 (8%)

Query: 1471 VTDSNLKVEWFK--NGQP--VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            V D +  V+W K  NG P  VTI  R R I   G   +  +   AEDSG Y+C A N  G
Sbjct: 1321 VGDPSPAVKWMKDSNGTPSLVTIDGR-RSIFSNGSFIIRTVK--AEDSGYYSCIANNNWG 1377

Query: 1527 TDEVSCRLTCRSTTDIVRST 1546
            +DE+   L  +   D  R T
Sbjct: 1378 SDEIILNLQVQVPPDQPRLT 1397



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI-KTVSDFGFVVLDIAYTQNHDSGEY 3222
            GQ     C  +   +PD +  W  +  P+  S R  KTV+  G ++ +I   +  DSG Y
Sbjct: 250  GQRVELPCKALGHPEPDYR--WLKDNMPLELSGRFQKTVT--GLLIENI---RPSDSGSY 302

Query: 3223 VCRAYNKYG 3231
            VC   N+YG
Sbjct: 303  VCEVSNRYG 311



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 9/94 (9%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG-----QPVTIGHRFR 1494
            V + P+FV +P+  ++ I G+ V   C  E      +  ++ K       QP+ +  R +
Sbjct: 697  VRVPPKFVVQPRD-QDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQ 755

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             + +   +   +++   EDSG Y C+  N VG D
Sbjct: 756  VLSNGSLLIKHVVE---EDSGYYLCKVSNDVGAD 786



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP       + + + G  V L C+   +G       W  +  P++   RF+         
Sbjct: 235  APSILDGFEHRKAMAGQRVELPCKA--LGHPEPDYRWLKDNMPLELSGRFQKTV----TG 288

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEA 1394
            L + ++ P DSG Y C+ +N+ G A
Sbjct: 289  LLIENIRPSDSGSYVCEVSNRYGTA 313



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            WLKD  P+E S R    F      L I+++   D+G Y C   N  G A     L +
Sbjct: 269  WLKDNMPLELSGR----FQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 321



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 1/98 (1%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V  + P F  P +  R +  Q   F   ++  GD  + + W ++G PI  S  +T  +  
Sbjct: 602  VTVKVPPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNID 660

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
               +L +  ++   +G YTC A NE       S L V+
Sbjct: 661  FTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR 698



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 35/171 (20%), Positives = 70/171 (40%), Gaps = 14/171 (8%)

Query: 3072 LIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            ++ +GD  + I W  +G+ I  S  +          L I       +G Y+C A N+   
Sbjct: 629  VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 688

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-- 3189
             E   +L          P+F    ++ +G+  G++    C+      P +  ++      
Sbjct: 689  VEHQSQLIV-----RVPPKFVVQPRDQDGIY-GKAVILNCSAEGYPVPTIVWKFSKGAGV 742

Query: 3190 ---QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
               QP+  + RI+ +S+   ++  +      DSG Y+C+  N  G D +++
Sbjct: 743  PQFQPIALNGRIQVLSNGSLLIKHVV---EEDSGYYLCKVSNDVGADVSKS 790



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P  I  ++++T +  G+  +   R++    P   ++W+ N   LP  HR   F + G + 
Sbjct: 515  PASIRPMKNITAIA-GRDTYIHCRVIGY--PYYSIKWYKNSNLLPFNHRQVAFENNGTLK 571

Query: 3342 LDILYCYEENSGEYEC 3357
            L  +   E + GEY C
Sbjct: 572  LSDVQ-KEVDEGEYTC 586



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
           T + P FI+P +       G+       +    D  + + W KDGRPI  S  +T I N 
Sbjct: 603 TVKVPPFIQPFE-FPRFSIGQRVFIPCVVVS-GDLPITITWQKDGRPIPGSLGVT-IDNI 659

Query: 826 GYV-SLNIMHLRAEDAGSYTVRAVNK 850
            +  SL I +L     G+YT  A N+
Sbjct: 660 DFTSSLRISNLSLMHNGNYTCIARNE 685



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 5/106 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS- 695
           P FI P +      G ++ F   +   GD  + I W K+G+ I  S   T I    + S 
Sbjct: 607 PPFIQPFEFPRFSIGQRV-FIPCVVVSGDLPITITWQKDGRPIPGSLGVT-IDNIDFTSS 664

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAE--TKAVLHVTPRATIERTSQ 739
           L + +L++  +G YTC A +     E  ++ ++ V P+  ++   Q
Sbjct: 665 LRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQ 710



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 13/92 (14%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW-FHNG------RPFATGSRVHT 3746
            PP+F V+ +D  D   G  V  +C  E  G P   I W F  G      +P A   R+  
Sbjct: 700  PPKFVVQPRDQ-DGIYGKAVILNCSAE--GYPVPTIVWKFSKGAGVPQFQPIALNGRIQV 756

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            L++   +   I ++   D+G Y C+ +N  G+
Sbjct: 757  LSNGSLL---IKHVVEEDSGYYLCKVSNDVGA 785


>BC070170-1|AAH70170.1|  637|Homo sapiens TTN protein protein.
          Length = 637

 Score =  111 bits (266), Expect = 8e-23
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 11/228 (4%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS--PDFQIHTFSTK 4465
            ++ P FT+ +Q   V E   A FE    G P+P + W+R+   I  S  P  QI     +
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            + L I  V   +S  ++  A N  G A  +A L+V+ +         PP+F    Q++ V
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET-------APPNFVQRLQSMTV 115

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  VRL  +VTG     V + ++G ++Q  +  +I +E   Y+LLI EAYP+DSG Y 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
              A NS G A   AE +V     ++ P  +TK   +  +I E  + +I
Sbjct: 176  VNATNSVGRATSTAELLVQ--GEEEVPAKKTKTIVSTAQISESRQTRI 221



 Score =  104 bits (249), Expect = 9e-21
 Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 19/258 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN--KILEEDGTYTL 4571
            P+FT   Q+V V  G     +  ++G    +V W ++G+ +        +I   DG   L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      +SG+Y   A N +G+A   AE +V             KA  APP  ++ L+ 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------KAETAPPNFVQRLQS 112

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V +G  +    ++ G P P V++Y+    I+ S  FQ+S+  D Y+L I+EA+PED G
Sbjct: 113  MTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK-- 4749
             Y   A NS GR T  A+L V   ++       T +    + E +  + + +I +     
Sbjct: 173  TYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDAR 232

Query: 4750 --PTIQWLREGALIPETP 4765
               T++ + +GA   + P
Sbjct: 233  SIATVEMVIDGAAGQQLP 250



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 57/193 (29%), Positives = 97/193 (50%), Gaps = 4/193 (2%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYTL 4680
            P   +PL+  +V EG    F   I G P+P V W++  ++I  S     Q+S +     L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             I      + G Y   A N +G+ T  A+L V       N   +  L+ + V +G   + 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNF--VQRLQSMTVRQGSQVRL 123

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + ++T    P +++ R+GA I  + DFQ+  EG+   LLI   Y ED+GT++  AT + G
Sbjct: 124  QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183

Query: 4801 QVETSAKLVVKSK 4813
            +  ++A+L+V+ +
Sbjct: 184  RATSTAELLVQGE 196



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 60/189 (31%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F +  Q   V EG    F+  ++G P PEV+WF + + I       + ++ S   A 
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I  VT ++SG  +  A N SG+      L V  K +   P FV+R  ++ VR+G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV--KAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L  R  G PTP + + +DG  I  + + +I  +G   +L I  A   D+  Y   A N  
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182

Query: 570 GSTATRARL 578
           G   + A L
Sbjct: 183 GRATSTAEL 191



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 10/203 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVY 3101
            T + P FT   + +V + EG  A +EA +  +G     + WF +G+ I  S    ++  +
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
            + G   L I      +SG YS +ATN  GQA  + +L  + K++   P F   +Q++  +
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMT-V 115

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            + G     +  V  +  P +K  +Y +G  ++ S   +   +     L IA     DSG 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGT 173

Query: 3222 YVCRAYNKYGEDFTRATINCYGK 3244
            Y   A N  G   + A +   G+
Sbjct: 174  YSVNATNSVGRATSTAELLVQGE 196



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 13/141 (9%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFF 962
            +TQ P F  P++  + + EG  A FEA +   G     V W +DG+ +  S+   +   F
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            + G   LTI +VT  ++G Y+ +A N  GQAT++A L +       AE+  P  ++++Q 
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK------AETAPPNFVQRLQS 112

Query: 1023 LEDASRYSKRTEEEVKITQKP 1043
            +    R   +   +V++T  P
Sbjct: 113  M--TVRQGSQVRLQVRVTGIP 131



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 3/115 (2%)

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
            Q  ST   + + + +PP FV  L+  T V +G     + +V  +  P   ++FY +G  +
Sbjct: 88   QATSTAELLVKAETAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEI 144

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
            QS+  F I+ +    SL I    PED+G YSV A N++G  TS   + V  +  +
Sbjct: 145  QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIF 823
           T+Q P F +PLQ +  L EG  A FEA ++    P   V W++DG+ I+ S+   +   F
Sbjct: 2   TTQAPTFTQPLQSVVVL-EGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           + G   L I  +   ++G Y+++A N  G+A STA + V A +
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 4722 PALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMIHEGNNAVL 4778
            P  T PL+ +VV EG  A F+  I+    P + W R+G +I  +  P  Q+      A L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             I    + ++G ++ +AT  +GQ  ++A+L+VK++T
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++  V +G  V L+  +T +  PT  V++Y +G  +Q    F+ + +    +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             I  AY ED+GTY   ATN+VG A +T+ + V  +
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765
            TQAP FT P++ + V E   A FEA +   G P   V W R+G  I  S        F  
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSD 60

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            G   L +  V   +SG Y+ +A N  G+A +++ L V+++ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 4/137 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH--EIITTHNHTTL 323
           P   Q  ++  + EG+ A F+  +SG P P V+WF++GQ +  S     +I  +     L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +    K++SG Y+L A N +G   ++  L V++ T      QR Q +T  Q   ++ R+
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQ--GSQVRL 123

Query: 384 EISEKALAPQFVKVCQD 400
           ++    +    VK  +D
Sbjct: 124 QVRVTGIPTPVVKFYRD 140



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 30/98 (30%), Positives = 55/98 (56%), Gaps = 2/98 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L ++   +G+ V L+ R+   G  T  V+++ +G  I++   F+ + E D  +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
             +   YPEDSG Y+  ATN +G A ++  L V  ++++
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 12/160 (7%)

Query: 1792 GEAVTSSTL------FVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQA 1843
            G+ +++STL      F   +A L + +  +  S    ++    S +     ++ V    A
Sbjct: 43   GQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102

Query: 1844 P-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            P  F+ +L   T + +G     + R+   P P   V++Y +G  +QS   ++ S +    
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +L I   Y EDSG Y+  A N++G+A S+  L VQ +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 2/130 (1%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           Q   T E +  +E A  P FV+  Q   V +G   R   RVTG P P V ++ +  +I+ 
Sbjct: 88  QATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             + +I   E   ++L+I      DSG  +  A N  G       L V  +E+V A K  
Sbjct: 147 SLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTK 205

Query: 495 ERFSTLNVRE 504
              ST  + E
Sbjct: 206 TIVSTAQISE 215



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F++ LQ +  +++G     + ++T +  PT  V++Y+DG  I +S            S
Sbjct: 104 PNFVQRLQSM-TVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I     ED+G+Y+V A N +G A STA + V     V A
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPA 201



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L S+  +++G +   + RV  I  P   + ++ +G +I++   ++ + +    +
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
            L I   Y EDSGTY   ATN +G A +T  L V G   +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 2/125 (1%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +PP   Q+ ++  +++G+  + QV+++G P P V ++++G  + +S   +I    +  +L
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +      DSG Y++ A N  G   ++  L V+   E  V  ++++ I  T Q     + 
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG--EEEVPAKKTKTIVSTAQISESRQT 219

Query: 384 EISEK 388
            I +K
Sbjct: 220 RIEKK 224



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L ++  +R+G     + R+T    P +K  +Y +G  +++   F+   +     
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            L I+  YPEDSG Y   A N+ G A +TA + VQG+  +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 11/122 (9%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKT 2428
            +T Q P FTQPLQ++  + EG TA F+  +   G P  +V WFR+ ++I  S+   +  +
Sbjct: 1    MTTQAPTFTQPLQSV-VVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQIS 57

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ 2488
               G   +TI  V   + G Y  +A+N  G+              ++ ET  P  ++++Q
Sbjct: 58   FSDGRAKLTIPAVTKANSGRYSLKATNGSGQ------ATSTAELLVKAETAPPNFVQRLQ 111

Query: 2489 KL 2490
             +
Sbjct: 112  SM 113



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 5/98 (5%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDF 2697
            QAP FT  L+S   ++EG     EA +     P  ++ WF++G  ++T     ++ +F  
Sbjct: 4    QAPTFTQPLQSV-VVLEGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G   L+I ++   +SG Y+ KATN  G+A STA + ++
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E +PP F Q  ++    QG   + + ++ G PTPVV + R  A +     + +    Q G
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQI---SQEG 156

Query: 128 DV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           D+ SLLI +  P D G Y+  A N  G A  +  +  +G
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L ++  ++G  +  +  V  +  PT  ++++ +   + S   ++ + +    SL I
Sbjct: 106  FVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               Y EDSG Y+  ATNS G AT++  L   G++ +    +  +       + ++ + R+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV--PAKKTKTIVSTAQISESRQTRI 221

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923
             K              E +I  AA  QL
Sbjct: 222  EKKIEAHFDARSIATVEMVIDGAAGQQL 249



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F+ +++S TV +   VR + RV     P   +++YR+G  + S   ++   +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDL 158

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             SL I   Y EDSG Y   A N  G   + A +
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 12/139 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-- 2164
            Q P F   L S+  L EG  A FE  +     P   + WF +GQ I           F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSD 60

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
            G   L I      +SG Y  KATN  G+A +T  L V        +T  PN +++++ + 
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------ETAPPNFVQRLQSMT 114

Query: 2225 A-QGHSTRIEVEEPKISPP 2242
              QG   R++V    I  P
Sbjct: 115  VRQGSQVRLQVRVTGIPTP 133



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 4/130 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P F   ++ + V +      + R+   G P   V++ R+G  I++S       +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L +    PEDSGTY+  A N +G A +++ L VQ +   ++ ++    +    Q+ +S
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--EVPAKKTKTIVSTAQISES 216

Query: 1828 SRYQRREDVE 1837
             + +  + +E
Sbjct: 217  RQTRIEKKIE 226



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 4/134 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+  L+S+T  +G ++  + R+   G PT  +++ ++G  I++S  F         S
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
           L +     +DSG Y+  A ++ G A + A L V  +   E  ++  +T+    Q+ +  +
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV--QGEEEVPAKKTKTIVSTAQISESRQ 218

Query: 756 YQHQESIEEQTSQR 769
            + ++ IE     R
Sbjct: 219 TRIEKKIEAHFDAR 232



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS--RFTSIFRFGYI 694
           P F  PL+SV  +EG    FE  I   G P  ++ W ++GQ I  S+       F  G  
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + ++   +SG Y+ +A + +G A + A L V
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHD 1097
            TQ P F  PL+    ++EG +A FEA +         V W+ +G+ I+++    +Q    
Sbjct: 3    TQAPTFTQPLQSV-VVLEGSTATFEAHISGFP--VPEVSWFRDGQVISTSTLPGVQISFS 59

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             G   L I +V   +SG Y++ A N +G+A  +A + V+  ++
Sbjct: 60   DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/108 (22%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +++ +  T  P     L+++ +++G +   + R+  +   T  V++Y +   ++S   F 
Sbjct: 94   ELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQ 151

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             +      +L I    PEDSGTY+  A N++G A ++   +V  ++ +
Sbjct: 152  ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGY 2299
            P F   L+    V EG TA FE  +     P   + ++ +G+ + ++      I+F  G 
Sbjct: 6    PTFTQPLQSVV-VLEGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L I      ++G YS+KA N  G  TS   + V A+ +  +  QR + +   +  +  
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 2360 EPFKRPEIPEPVTR 2373
               +   IP PV +
Sbjct: 123  LQVRVTGIPTPVVK 136



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDF--G 3613
            P FT     +++ E S+A FE  +   PV +    V WF +G+ + T +       F  G
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQISFSDG 61

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
               L I  V + ++G Y+ KATN  G+AT + +L VK
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-- 3475
            +AP FT PL ++  L EG  A FEA ++    P  +V W+ +G+ +   +       F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            G   L I      +SG Y  +A N  G+A +TA + V+ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GF 3752
            P FT  ++ ++ V EG    F+  +   G P   + WF +G+  +T +       F  G 
Sbjct: 6    PTFTQPLQ-SVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L I  +   ++G Y+ +ATN  G AT+TA++   A+
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 3/153 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T E +V+   A  PP FV    ++TV +G   R   RVTG P P V +  +G  I +   
Sbjct: 92   TAELLVKAETA--PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 4157 YKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
            ++++ +G +Y   I +    D+G   V              L V    +      K    
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVID 4248
                  ++  R E ++E  F+ R +   + VID
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVID 242



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F+ ++Q +T + +G     + R+  +  P +K  ++ +G ++     ++   +  + 
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLY 159

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             L I   Y E+SG Y   ATN +GR ++ A L    +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F   ++ ++ V +G  V    RV   G PT  + ++ +G    +        +    
Sbjct: 103  PPNFVQRLQ-SMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            +L I   Y  D+G Y+  ATN  G AT+TA++    + ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FVQ L +   V +G  + L+ R+   G PT  V+++ +G  +     F+   +    +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I  A   D+G Y+V A N +G A TS    +++  + V   + +  +   Q+ E    
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRA-TSTAELLVQGEEEVPAKKTKTIVSTAQISESRQT 219

Query: 1297 RTKQ 1300
            R ++
Sbjct: 220  RIEK 223



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033
            + P F +P+++  V EG     EA ++    P   V W+ +G+ +        + ++  G
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
               L I      ++G Y  KATN  G+A +T+ + V A++
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFD 1366
            QAP F++ L ++  +EG+    E  +   G     V WF +G+ I T      + ++   
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
               L + +V   +SG Y+ +ATN  G+A ++  L V A+
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/84 (27%), Positives = 35/84 (41%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F Q  ++    +G  A FE  + G P P VSW R    +       ++ +   G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155
            I  +   + G Y+  A N  G+A
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA 89



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            T  P F+  L+    + +G     + RV      T  V++Y +G +I S+   Q   +  
Sbjct: 101  TAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQISQEGD 157

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
              +L IA    EDSG Y+V A N+ G A  +A + V+    +
Sbjct: 158  LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 10/133 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP FV ++QS T     + ++   Q+   G P   V+++ +G  +     F    +    
Sbjct: 103  PPNFVQRLQSMTV---RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP-KHMKSIEKIREM 4090
            ++     YPEDSG Y   ATN  G   + A +   G      + ++P K  K+I    ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EEEVPAKKTKTIVSTAQI 213

Query: 4091 EASWQVTPEQVVE 4103
              S Q   E+ +E
Sbjct: 214  SESRQTRIEKKIE 226



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +TTQAP  T  L++V + EG  A FE  +   PV +    V W+ + + + + +      
Sbjct: 1    MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQI 56

Query: 1631 NF--GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            +F  G   L I +    +SG Y+ +A N  G+A ++   +V ++
Sbjct: 57   SFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSL 2833
            F   L ++V  EG    FE ++  S  P  ++ WF + + + + T       FS     L
Sbjct: 8    FTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I    + +SG Y+ KATN  G AT++  L
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 9/149 (6%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G + +   L  +AE+  PP F      + + + S    + R+  +   +  V+++ +G  
Sbjct: 87   GQATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAE 143

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            + +    +   +     L I   Y  D+G Y+  ATN  G AT + +L V+G      E 
Sbjct: 144  IQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EE 197

Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIE 3688
            ++P+       S  ++ E+   R E  IE
Sbjct: 198  EVPAKKTKTIVSTAQISESRQTRIEKKIE 226



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/109 (22%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V   T  P F   ++  +++++G     + R+   G  T  V++ +DG  +++S      
Sbjct: 97   VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQIS 153

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                  +L I      D+G Y+  A N++G+AT++A L +  ++++ A+
Sbjct: 154  QEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+S   + +G  V L+ +V     P +K  ++++G  + +    + + +  L +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L I     +DSG Y+  ATN +G A STA + ++
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++  +++G       R+   G PT  V+++R+   I+ S     + +    S
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+    ED G Y   A+N +G
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVG 183



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            + + P F   +Q V  L EG +A FEA +     P+  V WF +G+ +           F
Sbjct: 2    TTQAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISF 58

Query: 3338 --GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              G   L I    + NSG Y   ATN  G+ ++ A L
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/123 (21%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            +++ ++ T  P FV R +S+  V +G  V  + ++  +    +K  ++++G  +     F
Sbjct: 94   ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDF 150

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEAGL 1552
            +   +    +L I +   EDSG Y+  A N VG    +  L  +   ++  + T+     
Sbjct: 151  QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVST 210

Query: 1553 EQI 1555
             QI
Sbjct: 211  AQI 213


>BC058824-1|AAH58824.1|  558|Homo sapiens TTN protein protein.
          Length = 558

 Score =  111 bits (266), Expect = 8e-23
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 11/228 (4%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS--PDFQIHTFSTK 4465
            ++ P FT+ +Q   V E   A FE    G P+P + W+R+   I  S  P  QI     +
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            + L I  V   +S  ++  A N  G A  +A L+V+ +         PP+F    Q++ V
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET-------APPNFVQRLQSMTV 115

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  VRL  +VTG     V + ++G ++Q  +  +I +E   Y+LLI EAYP+DSG Y 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
              A NS G A   AE +V     ++ P  +TK   +  +I E  + +I
Sbjct: 176  VNATNSVGRATSTAELLVQ--GEEEVPAKKTKTIVSTAQISESRQTRI 221



 Score =  104 bits (249), Expect = 9e-21
 Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 19/258 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN--KILEEDGTYTL 4571
            P+FT   Q+V V  G     +  ++G    +V W ++G+ +        +I   DG   L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      +SG+Y   A N +G+A   AE +V             KA  APP  ++ L+ 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------KAETAPPNFVQRLQS 112

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V +G  +    ++ G P P V++Y+    I+ S  FQ+S+  D Y+L I+EA+PED G
Sbjct: 113  MTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK-- 4749
             Y   A NS GR T  A+L V   ++       T +    + E +  + + +I +     
Sbjct: 173  TYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDAR 232

Query: 4750 --PTIQWLREGALIPETP 4765
               T++ + +GA   + P
Sbjct: 233  SIATVEMVIDGAAGQQLP 250



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 57/193 (29%), Positives = 97/193 (50%), Gaps = 4/193 (2%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYTL 4680
            P   +PL+  +V EG    F   I G P+P V W++  ++I  S     Q+S +     L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             I      + G Y   A N +G+ T  A+L V       N   +  L+ + V +G   + 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNF--VQRLQSMTVRQGSQVRL 123

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + ++T    P +++ R+GA I  + DFQ+  EG+   LLI   Y ED+GT++  AT + G
Sbjct: 124  QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183

Query: 4801 QVETSAKLVVKSK 4813
            +  ++A+L+V+ +
Sbjct: 184  RATSTAELLVQGE 196



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 60/189 (31%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F +  Q   V EG    F+  ++G P PEV+WF + + I       + ++ S   A 
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I  VT ++SG  +  A N SG+      L V  K +   P FV+R  ++ VR+G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV--KAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L  R  G PTP + + +DG  I  + + +I  +G   +L I  A   D+  Y   A N  
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182

Query: 570 GSTATRARL 578
           G   + A L
Sbjct: 183 GRATSTAEL 191



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 10/203 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVY 3101
            T + P FT   + +V + EG  A +EA +  +G     + WF +G+ I  S    ++  +
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
            + G   L I      +SG YS +ATN  GQA  + +L  + K++   P F   +Q++  +
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMT-V 115

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            + G     +  V  +  P +K  +Y +G  ++ S   +   +     L IA     DSG 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGT 173

Query: 3222 YVCRAYNKYGEDFTRATINCYGK 3244
            Y   A N  G   + A +   G+
Sbjct: 174  YSVNATNSVGRATSTAELLVQGE 196



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 13/141 (9%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFF 962
            +TQ P F  P++  + + EG  A FEA +   G     V W +DG+ +  S+   +   F
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            + G   LTI +VT  ++G Y+ +A N  GQAT++A L +       AE+  P  ++++Q 
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK------AETAPPNFVQRLQS 112

Query: 1023 LEDASRYSKRTEEEVKITQKP 1043
            +    R   +   +V++T  P
Sbjct: 113  M--TVRQGSQVRLQVRVTGIP 131



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 3/115 (2%)

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
            Q  ST   + + + +PP FV  L+  T V +G     + +V  +  P   ++FY +G  +
Sbjct: 88   QATSTAELLVKAETAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEI 144

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
            QS+  F I+ +    SL I    PED+G YSV A N++G  TS   + V  +  +
Sbjct: 145  QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIF 823
           T+Q P F +PLQ +  L EG  A FEA ++    P   V W++DG+ I+ S+   +   F
Sbjct: 2   TTQAPTFTQPLQSVVVL-EGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           + G   L I  +   ++G Y+++A N  G+A STA + V A +
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 4722 PALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMIHEGNNAVL 4778
            P  T PL+ +VV EG  A F+  I+    P + W R+G +I  +  P  Q+      A L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             I    + ++G ++ +AT  +GQ  ++A+L+VK++T
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++  V +G  V L+  +T +  PT  V++Y +G  +Q    F+ + +    +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             I  AY ED+GTY   ATN+VG A +T+ + V  +
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765
            TQAP FT P++ + V E   A FEA +   G P   V W R+G  I  S        F  
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSD 60

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            G   L +  V   +SG Y+ +A N  G+A +++ L V+++ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 4/137 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH--EIITTHNHTTL 323
           P   Q  ++  + EG+ A F+  +SG P P V+WF++GQ +  S     +I  +     L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +    K++SG Y+L A N +G   ++  L V++ T      QR Q +T  Q   ++ R+
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQ--GSQVRL 123

Query: 384 EISEKALAPQFVKVCQD 400
           ++    +    VK  +D
Sbjct: 124 QVRVTGIPTPVVKFYRD 140



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 30/98 (30%), Positives = 55/98 (56%), Gaps = 2/98 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L ++   +G+ V L+ R+   G  T  V+++ +G  I++   F+ + E D  +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
             +   YPEDSG Y+  ATN +G A ++  L V  ++++
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 12/160 (7%)

Query: 1792 GEAVTSSTL------FVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQA 1843
            G+ +++STL      F   +A L + +  +  S    ++    S +     ++ V    A
Sbjct: 43   GQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102

Query: 1844 P-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            P  F+ +L   T + +G     + R+   P P   V++Y +G  +QS   ++ S +    
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +L I   Y EDSG Y+  A N++G+A S+  L VQ +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 2/130 (1%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           Q   T E +  +E A  P FV+  Q   V +G   R   RVTG P P V ++ +  +I+ 
Sbjct: 88  QATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             + +I   E   ++L+I      DSG  +  A N  G       L V  +E+V A K  
Sbjct: 147 SLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTK 205

Query: 495 ERFSTLNVRE 504
              ST  + E
Sbjct: 206 TIVSTAQISE 215



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F++ LQ +  +++G     + ++T +  PT  V++Y+DG  I +S            S
Sbjct: 104 PNFVQRLQSM-TVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I     ED+G+Y+V A N +G A STA + V     V A
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPA 201



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L S+  +++G +   + RV  I  P   + ++ +G +I++   ++ + +    +
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
            L I   Y EDSGTY   ATN +G A +T  L V G   +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 2/125 (1%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +PP   Q+ ++  +++G+  + QV+++G P P V ++++G  + +S   +I    +  +L
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +      DSG Y++ A N  G   ++  L V+   E  V  ++++ I  T Q     + 
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG--EEEVPAKKTKTIVSTAQISESRQT 219

Query: 384 EISEK 388
            I +K
Sbjct: 220 RIEKK 224



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L ++  +R+G     + R+T    P +K  +Y +G  +++   F+   +     
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            L I+  YPEDSG Y   A N+ G A +TA + VQG+  +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 11/122 (9%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKT 2428
            +T Q P FTQPLQ++  + EG TA F+  +   G P  +V WFR+ ++I  S+   +  +
Sbjct: 1    MTTQAPTFTQPLQSV-VVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQIS 57

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ 2488
               G   +TI  V   + G Y  +A+N  G+              ++ ET  P  ++++Q
Sbjct: 58   FSDGRAKLTIPAVTKANSGRYSLKATNGSGQ------ATSTAELLVKAETAPPNFVQRLQ 111

Query: 2489 KL 2490
             +
Sbjct: 112  SM 113



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 5/98 (5%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDF 2697
            QAP FT  L+S   ++EG     EA +     P  ++ WF++G  ++T     ++ +F  
Sbjct: 4    QAPTFTQPLQSV-VVLEGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G   L+I ++   +SG Y+ KATN  G+A STA + ++
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E +PP F Q  ++    QG   + + ++ G PTPVV + R  A +     + +    Q G
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQI---SQEG 156

Query: 128 DV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           D+ SLLI +  P D G Y+  A N  G A  +  +  +G
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L ++  ++G  +  +  V  +  PT  ++++ +   + S   ++ + +    SL I
Sbjct: 106  FVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               Y EDSG Y+  ATNS G AT++  L   G++ +    +  +       + ++ + R+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV--PAKKTKTIVSTAQISESRQTRI 221

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923
             K              E +I  AA  QL
Sbjct: 222  EKKIEAHFDARSIATVEMVIDGAAGQQL 249



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F+ +++S TV +   VR + RV     P   +++YR+G  + S   ++   +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDL 158

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             SL I   Y EDSG Y   A N  G   + A +
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 12/139 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-- 2164
            Q P F   L S+  L EG  A FE  +     P   + WF +GQ I           F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSD 60

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
            G   L I      +SG Y  KATN  G+A +T  L V        +T  PN +++++ + 
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------ETAPPNFVQRLQSMT 114

Query: 2225 A-QGHSTRIEVEEPKISPP 2242
              QG   R++V    I  P
Sbjct: 115  VRQGSQVRLQVRVTGIPTP 133



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 4/130 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P F   ++ + V +      + R+   G P   V++ R+G  I++S       +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L +    PEDSGTY+  A N +G A +++ L VQ +   ++ ++    +    Q+ +S
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--EVPAKKTKTIVSTAQISES 216

Query: 1828 SRYQRREDVE 1837
             + +  + +E
Sbjct: 217  RQTRIEKKIE 226



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 4/134 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+  L+S+T  +G ++  + R+   G PT  +++ ++G  I++S  F         S
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
           L +     +DSG Y+  A ++ G A + A L V  +   E  ++  +T+    Q+ +  +
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV--QGEEEVPAKKTKTIVSTAQISESRQ 218

Query: 756 YQHQESIEEQTSQR 769
            + ++ IE     R
Sbjct: 219 TRIEKKIEAHFDAR 232



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS--RFTSIFRFGYI 694
           P F  PL+SV  +EG    FE  I   G P  ++ W ++GQ I  S+       F  G  
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + ++   +SG Y+ +A + +G A + A L V
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHD 1097
            TQ P F  PL+    ++EG +A FEA +         V W+ +G+ I+++    +Q    
Sbjct: 3    TQAPTFTQPLQSV-VVLEGSTATFEAHISGFP--VPEVSWFRDGQVISTSTLPGVQISFS 59

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             G   L I +V   +SG Y++ A N +G+A  +A + V+  ++
Sbjct: 60   DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/108 (22%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +++ +  T  P     L+++ +++G +   + R+  +   T  V++Y +   ++S   F 
Sbjct: 94   ELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQ 151

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             +      +L I    PEDSGTY+  A N++G A ++   +V  ++ +
Sbjct: 152  ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGY 2299
            P F   L+    V EG TA FE  +     P   + ++ +G+ + ++      I+F  G 
Sbjct: 6    PTFTQPLQSVV-VLEGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L I      ++G YS+KA N  G  TS   + V A+ +  +  QR + +   +  +  
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 2360 EPFKRPEIPEPVTR 2373
               +   IP PV +
Sbjct: 123  LQVRVTGIPTPVVK 136



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDF--G 3613
            P FT     +++ E S+A FE  +   PV +    V WF +G+ + T +       F  G
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQISFSDG 61

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
               L I  V + ++G Y+ KATN  G+AT + +L VK
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-- 3475
            +AP FT PL ++  L EG  A FEA ++    P  +V W+ +G+ +   +       F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            G   L I      +SG Y  +A N  G+A +TA + V+ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GF 3752
            P FT  ++ ++ V EG    F+  +   G P   + WF +G+  +T +       F  G 
Sbjct: 6    PTFTQPLQ-SVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L I  +   ++G Y+ +ATN  G AT+TA++   A+
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 3/153 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T E +V+   A  PP FV    ++TV +G   R   RVTG P P V +  +G  I +   
Sbjct: 92   TAELLVKAETA--PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 4157 YKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
            ++++ +G +Y   I +    D+G   V              L V    +      K    
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVID 4248
                  ++  R E ++E  F+ R +   + VID
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVID 242



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F+ ++Q +T + +G     + R+  +  P +K  ++ +G ++     ++   +  + 
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLY 159

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             L I   Y E+SG Y   ATN +GR ++ A L    +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F   ++ ++ V +G  V    RV   G PT  + ++ +G    +        +    
Sbjct: 103  PPNFVQRLQ-SMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            +L I   Y  D+G Y+  ATN  G AT+TA++    + ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FVQ L +   V +G  + L+ R+   G PT  V+++ +G  +     F+   +    +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I  A   D+G Y+V A N +G A TS    +++  + V   + +  +   Q+ E    
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRA-TSTAELLVQGEEEVPAKKTKTIVSTAQISESRQT 219

Query: 1297 RTKQ 1300
            R ++
Sbjct: 220  RIEK 223



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033
            + P F +P+++  V EG     EA ++    P   V W+ +G+ +        + ++  G
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
               L I      ++G Y  KATN  G+A +T+ + V A++
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFD 1366
            QAP F++ L ++  +EG+    E  +   G     V WF +G+ I T      + ++   
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
               L + +V   +SG Y+ +ATN  G+A ++  L V A+
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/84 (27%), Positives = 35/84 (41%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F Q  ++    +G  A FE  + G P P VSW R    +       ++ +   G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155
            I  +   + G Y+  A N  G+A
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA 89



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            T  P F+  L+    + +G     + RV      T  V++Y +G +I S+   Q   +  
Sbjct: 101  TAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQISQEGD 157

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
              +L IA    EDSG Y+V A N+ G A  +A + V+    +
Sbjct: 158  LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 10/133 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP FV ++QS T     + ++   Q+   G P   V+++ +G  +     F    +    
Sbjct: 103  PPNFVQRLQSMTV---RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP-KHMKSIEKIREM 4090
            ++     YPEDSG Y   ATN  G   + A +   G      + ++P K  K+I    ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EEEVPAKKTKTIVSTAQI 213

Query: 4091 EASWQVTPEQVVE 4103
              S Q   E+ +E
Sbjct: 214  SESRQTRIEKKIE 226



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +TTQAP  T  L++V + EG  A FE  +   PV +    V W+ + + + + +      
Sbjct: 1    MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQI 56

Query: 1631 NF--GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            +F  G   L I +    +SG Y+ +A N  G+A ++   +V ++
Sbjct: 57   SFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSL 2833
            F   L ++V  EG    FE ++  S  P  ++ WF + + + + T       FS     L
Sbjct: 8    FTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I    + +SG Y+ KATN  G AT++  L
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 9/149 (6%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G + +   L  +AE+  PP F      + + + S    + R+  +   +  V+++ +G  
Sbjct: 87   GQATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAE 143

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            + +    +   +     L I   Y  D+G Y+  ATN  G AT + +L V+G      E 
Sbjct: 144  IQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EE 197

Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIE 3688
            ++P+       S  ++ E+   R E  IE
Sbjct: 198  EVPAKKTKTIVSTAQISESRQTRIEKKIE 226



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/109 (22%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V   T  P F   ++  +++++G     + R+   G  T  V++ +DG  +++S      
Sbjct: 97   VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQIS 153

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                  +L I      D+G Y+  A N++G+AT++A L +  ++++ A+
Sbjct: 154  QEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+S   + +G  V L+ +V     P +K  ++++G  + +    + + +  L +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L I     +DSG Y+  ATN +G A STA + ++
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++  +++G       R+   G PT  V+++R+   I+ S     + +    S
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+    ED G Y   A+N +G
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVG 183



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            + + P F   +Q V  L EG +A FEA +     P+  V WF +G+ +           F
Sbjct: 2    TTQAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISF 58

Query: 3338 --GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              G   L I    + NSG Y   ATN  G+ ++ A L
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/123 (21%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            +++ ++ T  P FV R +S+  V +G  V  + ++  +    +K  ++++G  +     F
Sbjct: 94   ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDF 150

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEAGL 1552
            +   +    +L I +   EDSG Y+  A N VG    +  L  +   ++  + T+     
Sbjct: 151  QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVST 210

Query: 1553 EQI 1555
             QI
Sbjct: 211  AQI 213


>BC013396-1|AAH13396.1|  305|Homo sapiens TTN protein protein.
          Length = 305

 Score =  111 bits (266), Expect = 8e-23
 Identities = 73/228 (32%), Positives = 112/228 (49%), Gaps = 11/228 (4%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS--PDFQIHTFSTK 4465
            ++ P FT+ +Q   V E   A FE    G P+P + W+R+   I  S  P  QI     +
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            + L I  V   +S  ++  A N  G A  +A L+V+ +         PP+F    Q++ V
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET-------APPNFVQRLQSMTV 115

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  VRL  +VTG     V + ++G ++Q  +  +I +E   Y+LLI EAYP+DSG Y 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
              A NS G A   AE +V     ++ P  +TK   +  +I E  + +I
Sbjct: 176  VNATNSVGRATSTAELLVQ--GEEEVPAKKTKTIVSTAQISESRQTRI 221



 Score =  104 bits (249), Expect = 9e-21
 Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 19/258 (7%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN--KILEEDGTYTL 4571
            P+FT   Q+V V  G     +  ++G    +V W ++G+ +        +I   DG   L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      +SG+Y   A N +G+A   AE +V             KA  APP  ++ L+ 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------KAETAPPNFVQRLQS 112

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V +G  +    ++ G P P V++Y+    I+ S  FQ+S+  D Y+L I+EA+PED G
Sbjct: 113  MTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSG 172

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK-- 4749
             Y   A NS GR T  A+L V   ++       T +    + E +  + + +I +     
Sbjct: 173  TYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDAR 232

Query: 4750 --PTIQWLREGALIPETP 4765
               T++ + +GA   + P
Sbjct: 233  SIATVEMVIDGAAGQQLP 250



 Score = 99.5 bits (237), Expect = 3e-19
 Identities = 57/193 (29%), Positives = 97/193 (50%), Gaps = 4/193 (2%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTADEYTL 4680
            P   +PL+  +V EG    F   I G P+P V W++  ++I  S     Q+S +     L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             I      + G Y   A N +G+ T  A+L V       N   +  L+ + V +G   + 
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNF--VQRLQSMTVRQGSQVRL 123

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + ++T    P +++ R+GA I  + DFQ+  EG+   LLI   Y ED+GT++  AT + G
Sbjct: 124  QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183

Query: 4801 QVETSAKLVVKSK 4813
            +  ++A+L+V+ +
Sbjct: 184  RATSTAELLVQGE 196



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 60/189 (31%), Positives = 89/189 (47%), Gaps = 3/189 (1%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA- 449
           AP F +  Q   V EG    F+  ++G P PEV+WF + + I       + ++ S   A 
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I  VT ++SG  +  A N SG+      L V  K +   P FV+R  ++ VR+G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV--KAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L  R  G PTP + + +DG  I  + + +I  +G   +L I  A   D+  Y   A N  
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182

Query: 570 GSTATRARL 578
           G   + A L
Sbjct: 183 GRATSTAEL 191



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 10/203 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVY 3101
            T + P FT   + +V + EG  A +EA +  +G     + WF +G+ I  S    ++  +
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
            + G   L I      +SG YS +ATN  GQA  + +L  + K++   P F   +Q++  +
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMT-V 115

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            + G     +  V  +  P +K  +Y +G  ++ S   +   +     L IA     DSG 
Sbjct: 116  RQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGT 173

Query: 3222 YVCRAYNKYGEDFTRATINCYGK 3244
            Y   A N  G   + A +   G+
Sbjct: 174  YSVNATNSVGRATSTAELLVQGE 196



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 13/141 (9%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFF 962
            +TQ P F  P++  + + EG  A FEA +   G     V W +DG+ +  S+   +   F
Sbjct: 2    TTQAPTFTQPLQSVV-VLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            + G   LTI +VT  ++G Y+ +A N  GQAT++A L +       AE+  P  ++++Q 
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK------AETAPPNFVQRLQS 112

Query: 1023 LEDASRYSKRTEEEVKITQKP 1043
            +    R   +   +V++T  P
Sbjct: 113  M--TVRQGSQVRLQVRVTGIP 131



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 3/115 (2%)

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
            Q  ST   + + + +PP FV  L+  T V +G     + +V  +  P   ++FY +G  +
Sbjct: 88   QATSTAELLVKAETAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEI 144

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSI 2340
            QS+  F I+ +    SL I    PED+G YSV A N++G  TS   + V  +  +
Sbjct: 145  QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIF 823
           T+Q P F +PLQ +  L EG  A FEA ++    P   V W++DG+ I+ S+   +   F
Sbjct: 2   TTQAPTFTQPLQSVVVL-EGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           + G   L I  +   ++G Y+++A N  G+A STA + V A +
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 4722 PALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMIHEGNNAVL 4778
            P  T PL+ +VV EG  A F+  I+    P + W R+G +I  +  P  Q+      A L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             I    + ++G ++ +AT  +GQ  ++A+L+VK++T
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++  V +G  V L+  +T +  PT  V++Y +G  +Q    F+ + +    +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             I  AY ED+GTY   ATN+VG A +T+ + V  +
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765
            TQAP FT P++ + V E   A FEA +   G P   V W R+G  I  S        F  
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSD 60

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            G   L +  V   +SG Y+ +A N  G+A +++ L V+++ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 4/137 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH--EIITTHNHTTL 323
           P   Q  ++  + EG+ A F+  +SG P P V+WF++GQ +  S     +I  +     L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +    K++SG Y+L A N +G   ++  L V++ T      QR Q +T  Q   ++ R+
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQ--GSQVRL 123

Query: 384 EISEKALAPQFVKVCQD 400
           ++    +    VK  +D
Sbjct: 124 QVRVTGIPTPVVKFYRD 140



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 30/98 (30%), Positives = 55/98 (56%), Gaps = 2/98 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L ++   +G+ V L+ R+   G  T  V+++ +G  I++   F+ + E D  +L
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
             +   YPEDSG Y+  ATN +G A ++  L V  ++++
Sbjct: 162  LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 12/160 (7%)

Query: 1792 GEAVTSSTL------FVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQA 1843
            G+ +++STL      F   +A L + +  +  S    ++    S +     ++ V    A
Sbjct: 43   GQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102

Query: 1844 P-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            P  F+ +L   T + +G     + R+   P P   V++Y +G  +QS   ++ S +    
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +L I   Y EDSG Y+  A N++G+A S+  L VQ +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 2/130 (1%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           Q   T E +  +E A  P FV+  Q   V +G   R   RVTG P P V ++ +  +I+ 
Sbjct: 88  QATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS 146

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             + +I   E   ++L+I      DSG  +  A N  G       L V  +E+V A K  
Sbjct: 147 SLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTK 205

Query: 495 ERFSTLNVRE 504
              ST  + E
Sbjct: 206 TIVSTAQISE 215



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F++ LQ +  +++G     + ++T +  PT  V++Y+DG  I +S            S
Sbjct: 104 PNFVQRLQSM-TVRQGSQVRLQVRVTGI--PTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
           L I     ED+G+Y+V A N +G A STA + V     V A
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPA 201



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  L S+  +++G +   + RV  I  P   + ++ +G +I++   ++ + +    +
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
            L I   Y EDSGTY   ATN +G A +T  L V G   +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 2/125 (1%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +PP   Q+ ++  +++G+  + QV+++G P P V ++++G  + +S   +I    +  +L
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            +      DSG Y++ A N  G   ++  L V+   E  V  ++++ I  T Q     + 
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG--EEEVPAKKTKTIVSTAQISESRQT 219

Query: 384 EISEK 388
            I +K
Sbjct: 220 RIEKK 224



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L ++  +R+G     + R+T    P +K  +Y +G  +++   F+   +     
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            L I+  YPEDSG Y   A N+ G A +TA + VQG+  +
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 11/122 (9%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS--RITKT 2428
            +T Q P FTQPLQ++  + EG TA F+  +   G P  +V WFR+ ++I  S+   +  +
Sbjct: 1    MTTQAPTFTQPLQSV-VVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQIS 57

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQ 2488
               G   +TI  V   + G Y  +A+N  G+              ++ ET  P  ++++Q
Sbjct: 58   FSDGRAKLTIPAVTKANSGRYSLKATNGSGQ------ATSTAELLVKAETAPPNFVQRLQ 111

Query: 2489 KL 2490
             +
Sbjct: 112  SM 113



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 5/98 (5%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDF 2697
            QAP FT  L+S   ++EG     EA +     P  ++ WF++G  ++T     ++ +F  
Sbjct: 4    QAPTFTQPLQSV-VVLEGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G   L+I ++   +SG Y+ KATN  G+A STA + ++
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E +PP F Q  ++    QG   + + ++ G PTPVV + R  A +     + +    Q G
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQI---SQEG 156

Query: 128 DV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
           D+ SLLI +  P D G Y+  A N  G A  +  +  +G
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L ++  ++G  +  +  V  +  PT  ++++ +   + S   ++ + +    SL I
Sbjct: 106  FVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
               Y EDSG Y+  ATNS G AT++  L   G++ +    +  +       + ++ + R+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV--PAKKTKTIVSTAQISESRQTRI 221

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923
             K              E +I  AA  QL
Sbjct: 222  EKKIEAHFDARSIATVEMVIDGAAGQQL 249



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            + PP F+ +++S TV +   VR + RV     P   +++YR+G  + S   ++   +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV--VKFYRDGAEIQSSLDFQISQEGDL 158

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             SL I   Y EDSG Y   A N  G   + A +
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 12/139 (8%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-- 2164
            Q P F   L S+  L EG  A FE  +     P   + WF +GQ I           F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSD 60

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
            G   L I      +SG Y  KATN  G+A +T  L V        +T  PN +++++ + 
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------ETAPPNFVQRLQSMT 114

Query: 2225 A-QGHSTRIEVEEPKISPP 2242
              QG   R++V    I  P
Sbjct: 115  VRQGSQVRLQVRVTGIPTP 133



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 4/130 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P F   ++ + V +      + R+   G P   V++ R+G  I++S       +   
Sbjct: 101  TAPPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L +    PEDSGTY+  A N +G A +++ L VQ +   ++ ++    +    Q+ +S
Sbjct: 159  YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEE--EVPAKKTKTIVSTAQISES 216

Query: 1828 SRYQRREDVE 1837
             + +  + +E
Sbjct: 217  RQTRIEKKIE 226



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 4/134 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F+  L+S+T  +G ++  + R+   G PT  +++ ++G  I++S  F         S
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
           L +     +DSG Y+  A ++ G A + A L V  +   E  ++  +T+    Q+ +  +
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLV--QGEEEVPAKKTKTIVSTAQISESRQ 218

Query: 756 YQHQESIEEQTSQR 769
            + ++ IE     R
Sbjct: 219 TRIEKKIEAHFDAR 232



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS--RFTSIFRFGYI 694
           P F  PL+SV  +EG    FE  I   G P  ++ W ++GQ I  S+       F  G  
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L + ++   +SG Y+ +A + +G A + A L V
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHD 1097
            TQ P F  PL+    ++EG +A FEA +         V W+ +G+ I+++    +Q    
Sbjct: 3    TQAPTFTQPLQSV-VVLEGSTATFEAHISGFP--VPEVSWFRDGQVISTSTLPGVQISFS 59

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             G   L I +V   +SG Y++ A N +G+A  +A + V+  ++
Sbjct: 60   DGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/108 (22%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +++ +  T  P     L+++ +++G +   + R+  +   T  V++Y +   ++S   F 
Sbjct: 94   ELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQ 151

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             +      +L I    PEDSGTY+  A N++G A ++   +V  ++ +
Sbjct: 152  ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 5/134 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGY 2299
            P F   L+    V EG TA FE  +     P   + ++ +G+ + ++      I+F  G 
Sbjct: 6    PTFTQPLQSVV-VLEGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
              L I      ++G YS+KA N  G  TS   + V A+ +  +  QR + +   +  +  
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVR 122

Query: 2360 EPFKRPEIPEPVTR 2373
               +   IP PV +
Sbjct: 123  LQVRVTGIPTPVVK 136



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDF--G 3613
            P FT     +++ E S+A FE  +   PV +    V WF +G+ + T +       F  G
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQISFSDG 61

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
               L I  V + ++G Y+ KATN  G+AT + +L VK
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-- 3475
            +AP FT PL ++  L EG  A FEA ++    P  +V W+ +G+ +   +       F  
Sbjct: 4    QAPTFTQPLQSVVVL-EGSTATFEAHISGFPVP--EVSWFRDGQVISTSTLPGVQISFSD 60

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            G   L I      +SG Y  +A N  G+A +TA + V+ +
Sbjct: 61   GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GF 3752
            P FT  ++ ++ V EG    F+  +   G P   + WF +G+  +T +       F  G 
Sbjct: 6    PTFTQPLQ-SVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L I  +   ++G Y+ +ATN  G AT+TA++   A+
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 3/153 (1%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T E +V+   A  PP FV    ++TV +G   R   RVTG P P V +  +G  I +   
Sbjct: 92   TAELLVKAETA--PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 4157 YKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
            ++++ +G +Y   I +    D+G   V              L V    +      K    
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVID 4248
                  ++  R E ++E  F+ R +   + VID
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVID 242



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP F+ ++Q +T + +G     + R+  +  P +K  ++ +G ++     ++   +  + 
Sbjct: 103  PPNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLY 159

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             L I   Y E+SG Y   ATN +GR ++ A L    +E +
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F   ++ ++ V +G  V    RV   G PT  + ++ +G    +        +    
Sbjct: 103  PPNFVQRLQ-SMTVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            +L I   Y  D+G Y+  ATN  G AT+TA++    + ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FVQ L +   V +G  + L+ R+   G PT  V+++ +G  +     F+   +    +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I  A   D+G Y+V A N +G A TS    +++  + V   + +  +   Q+ E    
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRA-TSTAELLVQGEEEVPAKKTKTIVSTAQISESRQT 219

Query: 1297 RTKQ 1300
            R ++
Sbjct: 220  RIEK 223



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 4/100 (4%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033
            + P F +P+++  V EG     EA ++    P   V W+ +G+ +        + ++  G
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHISGF--PVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
               L I      ++G Y  KATN  G+A +T+ + V A++
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAET 101



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFD 1366
            QAP F++ L ++  +EG+    E  +   G     V WF +G+ I T      + ++   
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHIS--GFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
               L + +V   +SG Y+ +ATN  G+A ++  L V A+
Sbjct: 62   RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/84 (27%), Positives = 35/84 (41%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F Q  ++    +G  A FE  + G P P VSW R    +       ++ +   G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155
            I  +   + G Y+  A N  G+A
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA 89



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            T  P F+  L+    + +G     + RV      T  V++Y +G +I S+   Q   +  
Sbjct: 101  TAPPNFVQRLQSMT-VRQGSQVRLQVRVTGIP--TPVVKFYRDGAEIQSSLDFQISQEGD 157

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
              +L IA    EDSG Y+V A N+ G A  +A + V+    +
Sbjct: 158  LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEV 199



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 10/133 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP FV ++QS T     + ++   Q+   G P   V+++ +G  +     F    +    
Sbjct: 103  PPNFVQRLQSMTV---RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY 159

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP-KHMKSIEKIREM 4090
            ++     YPEDSG Y   ATN  G   + A +   G      + ++P K  K+I    ++
Sbjct: 160  SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EEEVPAKKTKTIVSTAQI 213

Query: 4091 EASWQVTPEQVVE 4103
              S Q   E+ +E
Sbjct: 214  SESRQTRIEKKIE 226



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFTETN 1630
            +TTQAP  T  L++V + EG  A FE  +   PV +    V W+ + + + + +      
Sbjct: 1    MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPE----VSWFRDGQVISTSTLPGVQI 56

Query: 1631 NF--GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            +F  G   L I +    +SG Y+ +A N  G+A ++   +V ++
Sbjct: 57   SFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAE 100



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSL 2833
            F   L ++V  EG    FE ++  S  P  ++ WF + + + + T       FS     L
Sbjct: 8    FTQPLQSVVVLEGSTATFEAHI--SGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I    + +SG Y+ KATN  G AT++  L
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 9/149 (6%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G + +   L  +AE+  PP F      + + + S    + R+  +   +  V+++ +G  
Sbjct: 87   GQATSTAELLVKAETA-PPNFVQRLQSMTVRQGSQVRLQVRVTGI--PTPVVKFYRDGAE 143

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            + +    +   +     L I   Y  D+G Y+  ATN  G AT + +L V+G      E 
Sbjct: 144  IQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG------EE 197

Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIE 3688
            ++P+       S  ++ E+   R E  IE
Sbjct: 198  EVPAKKTKTIVSTAQISESRQTRIEKKIE 226



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/109 (22%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V   T  P F   ++  +++++G     + R+   G  T  V++ +DG  +++S      
Sbjct: 97   VKAETAPPNFVQRLQS-MTVRQGSQVRLQVRVT--GIPTPVVKFYRDGAEIQSSLDFQIS 153

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAE 1010
                  +L I      D+G Y+  A N++G+AT++A L +  ++++ A+
Sbjct: 154  QEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+S   + +G  V L+ +V     P +K  ++++G  + +    + + +  L +
Sbjct: 104  PNFVQRLQSMT-VRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L I     +DSG Y+  ATN +G A STA + ++
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q LQ++  +++G       R+   G PT  V+++R+   I+ S     + +    S
Sbjct: 104  PNFVQRLQSM-TVRQGSQVRLQVRV--TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS 160

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I+    ED G Y   A+N +G
Sbjct: 161  LLIAEAYPEDSGTYSVNATNSVG 183



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            + + P F   +Q V  L EG +A FEA +     P+  V WF +G+ +           F
Sbjct: 2    TTQAPTFTQPLQSVVVL-EGSTATFEAHISGFPVPE--VSWFRDGQVISTSTLPGVQISF 58

Query: 3338 --GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              G   L I    + NSG Y   ATN  G+ ++ A L
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL 95



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/123 (21%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            +++ ++ T  P FV R +S+  V +G  V  + ++  +    +K  ++++G  +     F
Sbjct: 94   ELLVKAETAPPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVK--FYRDGAEIQSSLDF 150

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEAGL 1552
            +   +    +L I +   EDSG Y+  A N VG    +  L  +   ++  + T+     
Sbjct: 151  QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVST 210

Query: 1553 EQI 1555
             QI
Sbjct: 211  AQI 213


>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
          Length = 3100

 Score =  109 bits (263), Expect = 2e-22
 Identities = 83/298 (27%), Positives = 131/298 (43%), Gaps = 13/298 (4%)

Query: 278  QEGADAQFQVQLSG-NPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +EG   ++  ++   +   +VTW+   ++L NS K+EI        L V++  K D G Y
Sbjct: 2807 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
                 N  G   +   L V+   E Y  D   +      +R T+  + + E+   P+F  
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREVY--DYYCRRTMKKIKRRTDT-MRLLERP--PEFTL 2921

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES--GNHALMITN 454
               ++    G+  RF   +T  P P VTW+ + ++I+   N K    ES  G + L I +
Sbjct: 2922 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 2981

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVI----EKEQVVAPKFVERFSTLNVREGEPVVL 510
            VT  D    T VARNK GE + + +L V       +  + P F    +    +EG+ V  
Sbjct: 2982 VTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCF 3041

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDG-GASTLDIPRAKASDAAWYQCTAQN 567
              R  G P P + W+KDG P+   P + I  +G     L I      D  +Y+ TA N
Sbjct: 3042 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATN 3099



 Score =  101 bits (243), Expect = 5e-20
 Identities = 81/274 (29%), Positives = 119/274 (43%), Gaps = 24/274 (8%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            V W    ++++   + +I  EDG   L + +    D G Y C  +N  GE    AE  V 
Sbjct: 2827 VTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVK 2886

Query: 4605 ---------LPATKDKPKPQT---KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
                        T  K K +T   +    PPE   PL +K    G+ + F   I   P P
Sbjct: 2887 GVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEP 2946

Query: 4653 TVQWYKGDKLIKP---SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
             V WYK  + IKP    K +        Y L I+    +D+ +Y  VA N  G  +  AK
Sbjct: 2947 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 3006

Query: 4710 LKVT-QPDQADNLPALTP-----LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
            L VT  P   D+   L P     L +    EGQ   F+ +++    PT++W ++G  +  
Sbjct: 3007 LTVTLHPPPTDS--TLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSL 3064

Query: 4764 TPDFQMIHEG-NNAVLLIGNTYEEDTGTFTCRAT 4796
             P+ ++IHEG +   L I +T  EDTG +   AT
Sbjct: 3065 GPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTAT 3098



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 90/332 (27%), Positives = 132/332 (39%), Gaps = 41/332 (12%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG    Y C+IE Y D + +V WYF  + L++  +Y  + + G A L +  +   D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK 1977
             CK +N+ G+  S   L V+    +  D      ++KI+   D  R          +   
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREVY-DYYCRRTMKKIKRRTDTMR---------LLERP 2916

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F  P+ N     G  V    T+T   +P   V WY +G+ ++ G              
Sbjct: 2917 PEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDN------------ 2962

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
            D  Y +  D G Y     +   +     +V    K G       E   K   +L     P
Sbjct: 2963 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG-------EDSCK--AKLTVTLHP 3013

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
             P +      RP+F   L + E  +EG    FE RV  I  P  T+ W  +GQ +  G  
Sbjct: 3014 PPTDST---LRPMFKRLLANAE-CQEGQSVCFEIRVSGIPPP--TLKWEKDGQPLSLGPN 3067

Query: 2158 YRTTHD-FGYVALDILYTYAEDSGTYMCKATN 2188
                H+   Y AL I  T  ED+G Y   ATN
Sbjct: 3068 IEIIHEGLDYYALHIRDTLPEDTGYYRVTATN 3099



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 90/350 (25%), Positives = 140/350 (40%), Gaps = 49/350 (14%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P+  Q++    E  EG H  Y  ++    D S +  WY    +L+   ++  T++ G   
Sbjct: 2796 PVSGQIMHAVGE--EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAI 2852

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L +  +   D G Y CK +N  G               + D   R  + ++I+ +   M 
Sbjct: 2853 LYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCR-RTMKKIKRRTDTMR 2911

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                      +++ P FT  L +    V G++V     +    +P+  + W+K+G  +  
Sbjct: 2912 L---------LERPPEFTLPLYNKTAYV-GENVRFGVTITVHPEPH--VTWYKSGQKIKP 2959

Query: 2688 GAR-LKSTF--DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
            G    K TF  D GL  L+INS+  DD   YT  A N  GE    A + +         +
Sbjct: 2960 GDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV---------T 3010

Query: 2745 LHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPT 2804
            LHP   D                       +F   L N  C+EG ++ FE  V     PT
Sbjct: 3011 LHPPPTD------------------STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPT 3052

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHD-FSYVSLDITHTYEEDSGIYTCKATNS 2853
            LK  W  + +PL  G   +  H+   Y +L I  T  ED+G Y   ATN+
Sbjct: 3053 LK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNT 3100



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 63/194 (32%), Positives = 84/194 (43%), Gaps = 15/194 (7%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK--ILEED-GTY 4569
            PP FTL   N     G+ VR    +T      V W K+G+K++P   +K    E D G Y
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 2975

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL--PATKDKPKPQTKAANAPPEIIE 4627
             L I      D  +Y  VA N  GE  C A+  V+L  P T    +P  K   A  E   
Sbjct: 2976 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAE--- 3032

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAF 4686
                    EGQ++ F  ++ G P PT++W K G  L        +    D Y L I +  
Sbjct: 3033 ------CQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTL 3086

Query: 4687 PEDEGDYKCVAYNS 4700
            PED G Y+  A N+
Sbjct: 3087 PEDTGYYRVTATNT 3100



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 80/324 (24%), Positives = 140/324 (43%), Gaps = 40/324 (12%)

Query: 2924 VEGQVLHLEGQ--------VEPKN-DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLV 2974
            V GQ++H  G+         + +N D   ++ WYF  + LE   ++++T + G   L + 
Sbjct: 2797 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVK 2856

Query: 2975 DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRK 3034
            D+ + D G Y CK  N  GE  + + ++      + +   + + T  ++KI+   D++R 
Sbjct: 2857 DITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYD--YYCRRT--MKKIKRRTDTMRL 2912

Query: 3035 EPGQQPDDDTGRPPEFT-TVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA 3093
                       RPPEFT  ++     + E    +    +  T      + W+ +G+ I+ 
Sbjct: 2913 ---------LERPPEFTLPLYNKTAYVGE----NVRFGVTITVHPEPHVTWYKSGQKIKP 2959

Query: 3094 SHRIRTVYAF----GMVVLEILGTKTTDSGTYSCRATNKWGQ----AEISVKLECVDKSK 3145
                +  Y F    G+  L I    T D   Y+  A NK+G+    A+++V L       
Sbjct: 2960 GDNDKK-YTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDS 3018

Query: 3146 GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD-F 3204
              +P F   + N E  ++GQS  FE  V  +  P +K  W  +GQP+     I+ + +  
Sbjct: 3019 TLRPMFKRLLANAE-CQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGL 3075

Query: 3205 GFVVLDIAYTQNHDSGEYVCRAYN 3228
             +  L I  T   D+G Y   A N
Sbjct: 3076 DYYALHIRDTLPEDTGYYRVTATN 3099



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 92/339 (27%), Positives = 145/339 (42%), Gaps = 53/339 (15%)

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
            EG ++   C++E   D + +V W+   R +    +++  Y+ G   L +   T  D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 1251 TVRAVNHLG--SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVM 1308
              + VN  G  S++    V+ +     V D    + +++I+      RRT  +R    + 
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVRE---VYDYYCRRTMKKIK------RRTDTMR---LLE 2914

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP-AYEFD- 1366
            + P+F+  L+N     G NV     +    +    V W+ +G+ IK G   +   +E D 
Sbjct: 2915 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDK 2972

Query: 1367 -YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
                L + SV  +D   YT  A N+ GE   SC     AK  + L   HP          
Sbjct: 2973 GLYQLTINSVTTDDDAEYTVVARNKYGE--DSCK----AKLTVTL---HP---------- 3013

Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485
                   TD      T++P F  R  +     EGQ V FE ++  +    LK  W K+GQ
Sbjct: 3014 -----PPTD-----STLRPMF-KRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQ 3060

Query: 1486 PVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVN 1523
            P+++G     IH+   Y AL I D + ED+G Y   A N
Sbjct: 3061 PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATN 3099



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 54/187 (28%), Positives = 80/187 (42%), Gaps = 5/187 (2%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSI 4467
            +PP FT  +     +  E  RF V     P P + WY+    IK   + + +TF S K +
Sbjct: 2915 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGL 2974

Query: 4468 --LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
              L I  V  +D A +  VA N+ G   C A L V           + P F     N   
Sbjct: 2975 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-TLHPPPTDSTLRPMFKRLLANAEC 3033

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKY 4584
              GQ V  + +V+G  P  + W K+G+ +      +I+ E    Y L I +  P+D+G Y
Sbjct: 3034 QEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 3093

Query: 4585 ECVAINS 4591
               A N+
Sbjct: 3094 RVTATNT 3100



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 52/182 (28%), Positives = 81/182 (44%), Gaps = 2/182 (1%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNHKILVNESGNHA 449
            AP F +  ++ +V         C+VTG P P V W+   ++I  D   ++I   + G H 
Sbjct: 2154 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 2213

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L+I +VT  D+ V    A N+ G  +    L V    ++  PK +E    ++   GE V 
Sbjct: 2214 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVS 2273

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR-AKASDAAWYQCTAQNV 568
            +     G P P ITWQK    I  N   ++      ++L  P   +  DA +Y   A+N 
Sbjct: 2274 IKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNR 2333

Query: 569  AG 570
             G
Sbjct: 2334 FG 2335



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 70/280 (25%), Positives = 120/280 (42%), Gaps = 20/280 (7%)

Query: 922  KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
            +EGG   +  ++E    ST +V W    R +E S +    +  G   L +K +T  D G 
Sbjct: 2807 EEGGHVKYVCKIENYDQST-QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 2865

Query: 982  YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            Y C+  N  G+ ++ A L +   +++              Y     +  KR  + +++ +
Sbjct: 2866 YRCKVVNDYGEDSSYAELFVKGVREVYD-----------YYCRRTMKKIKRRTDTMRLLE 2914

Query: 1042 K-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY---HD 1097
            + P F  PL      V G++  F   +    +  +T  WY +G++I   +  + Y    D
Sbjct: 2915 RPPEFTLPLYNKTAYV-GENVRFGVTITVHPEPHVT--WYKSGQKIKPGDNDKKYTFESD 2971

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
             G   L I SV  +D   YTVVARN  GE    A +TV T     T S  R ++++    
Sbjct: 2972 KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-TLHPPPTDSTLRPMFKRLLAN 3030

Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHL 1197
             E +  + +     +S   P  ++   +  P+S G NI +
Sbjct: 3031 AECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEI 3070



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 46/192 (23%), Positives = 84/192 (43%), Gaps = 3/192 (1%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I + +KD     G+A + SC+IVG+PLP ++WY+  K +  S+ ++MS     +TL +
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                 EDEG Y C+A N  G V  ++KL +    Q    P            G   +   
Sbjct: 1820 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFH--PGYPLKEKYYGAVGSTLRLHV 1877

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE-DTGTFTCRATTAAGQ 4801
                +  P + W     L+  + +  + +  +   L++ N   +   G +  + +   G 
Sbjct: 1878 MYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 1937

Query: 4802 VETSAKLVVKSK 4813
            V+    + ++ K
Sbjct: 1938 VDAILDVEIQDK 1949



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 64/235 (27%), Positives = 103/235 (43%), Gaps = 28/235 (11%)

Query: 3839 HTVEESEG-VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE 3897
            H V E  G V++ C++E   D   ++ WY   + L +  +Y   Y+ G   L +  +   
Sbjct: 2803 HAVGEEGGHVKYVCKIE-NYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 2861

Query: 3898 DSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEV 3957
            D G Y C+ VND+GED + A +  K + + +      R MK+          IK+ T  +
Sbjct: 2862 DDGTYRCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKK----------IKRRTDTM 2910

Query: 3958 YLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG---K 4014
             L E         +PP F   + ++T+ V  E  +F   +    +P+  V W+ +G   K
Sbjct: 2911 RLLE---------RPPEFTLPLYNKTAYVG-ENVRFGVTITVHPEPH--VTWYKSGQKIK 2958

Query: 4015 PLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            P  +  ++T   D G   +    V  +D  EY   A N YG D  KA +  T  P
Sbjct: 2959 PGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP 3013



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 56/215 (26%), Positives = 95/215 (44%), Gaps = 17/215 (7%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EGG V + C++E   D + ++ W+   R      +     + G   L +  I   D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C+  N +G  ++ A++     R+ V +    + M  +KIK     R +D  +   ++  
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTM--KKIK-----RRTDTMR---LLER 2915

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG---HRYRTVYDMG 3885
            PP+F   + + T    E VRF   +    +P   + WY++G+ +  G    +Y    D G
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 2973

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
               L I  V  +D  EY   A N +GED  KA ++
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLT 3008



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 57/205 (27%), Positives = 88/205 (42%), Gaps = 20/205 (9%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
            D   +V W++  ++L +  +Y   ++ G+ IL +    + + G Y C   N  G DS+ A
Sbjct: 2822 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 2881

Query: 3371 NLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIE 3430
             L        + D    R M+            + RR DT    E+   P FT+PL N +
Sbjct: 2882 ELFVKGVRE-VYDYYCRRTMK-----------KIKRRTDTMRLLER--PPEFTLPLYN-K 2926

Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC---DFGFVILEISPTYP 3487
                GEN  F   +T   +P+  V WY +G+ +K G   + +    D G   L I+    
Sbjct: 2927 TAYVGENVRFGVTITVHPEPH--VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTT 2984

Query: 3488 EDSGEYLCRAYNNYGEAVTTASMKV 3512
            +D  EY   A N YGE    A + V
Sbjct: 2985 DDDAEYTVVARNKYGEDSCKAKLTV 3009



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 62/243 (25%), Positives = 103/243 (42%), Gaps = 25/243 (10%)

Query: 4481 FAAVAENRGGTAKCSANLV-VEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG 4539
            F   AEN  G ++     + ++ K   G      P      ++V    G+  +L  ++ G
Sbjct: 1730 FRVFAENETGLSRPRRTAMSIKTKLTSGEA----PGIRKEMKDVTTKLGEAAQLSCQIVG 1785

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
                D+ W + GK++    + K+  +  T+TL ++    +D G Y C+A N  GE    +
Sbjct: 1786 RPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSS 1845

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV-AEGQAIEFSCKIVGKPLPTVQWYK 4658
            + +  L AT     PQ            PLK+K   A G  +      +G+P+P + W+ 
Sbjct: 1846 KLL--LQAT-----PQFHPG-------YPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFH 1891

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPE--DEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            G KL++ S+   +  T + YT  + +        G YK    N  G  TV A L V   D
Sbjct: 1892 GQKLLQNSENITIENT-EHYTHLVMKNVQRKTHAGKYKVQLSNVFG--TVDAILDVEIQD 1948

Query: 4717 QAD 4719
            + D
Sbjct: 1949 KPD 1951



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 55/218 (25%), Positives = 95/218 (43%), Gaps = 18/218 (8%)

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            ++G    + C +   D    ++ WY   + + +S + +   + G  +L +      D G 
Sbjct: 2807 EEGGHVKYVCKIENYDQ-STQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 2865

Query: 3222 YVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE- 3280
            Y C+  N YGED + A +   G   VY      D   +     +++  +++T +    E 
Sbjct: 2866 YRCKVVNDYGEDSSYAELFVKGVREVY------DYYCR----RTMKKIKRRTDTMRLLER 2915

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG---HRYRTFHDF 3337
            PP+F   + + T  V G++  F   +     P+  V W+ +G+K+  G    +Y    D 
Sbjct: 2916 PPEFTLPLYNKTAYV-GENVRFGVTITV--HPEPHVTWYKSGQKIKPGDNDKKYTFESDK 2972

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
            G+  L I     ++  EY  VA NK G DS KA L  T
Sbjct: 2973 GLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 3010



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 52/201 (25%), Positives = 88/201 (43%), Gaps = 16/201 (7%)

Query: 1739 DPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
            D   +V W      +E S +    ++ G   L +K +   D GTY C+ +N+ GE  + +
Sbjct: 2822 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 2881

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE 1858
             LFV+    +  +      ++KI         +RR D    + + P F   L   T    
Sbjct: 2882 ELFVKGVREV-YDYYCRRTMKKI---------KRRTDTMRLLERPPEFTLPLYNKTAY-V 2930

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG---HRYRTSNDFGFAALDILTVYGEDSG 1915
            G++  +   I  +P+P+  V WY +G+ ++ G    +Y   +D G   L I +V  +D  
Sbjct: 2931 GENVRFGVTITVHPEPH--VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA 2988

Query: 1916 EYTCKAINNLGQAVSSIRLNV 1936
            EYT  A N  G+     +L V
Sbjct: 2989 EYTVVARNKYGEDSCKAKLTV 3009



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 55/229 (24%), Positives = 92/229 (40%), Gaps = 16/229 (6%)

Query: 2122 KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
            +EG    + C++E   D    + W+   +++    +Y  T++ G   L +      D GT
Sbjct: 2807 EEGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 2865

Query: 2182 YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISP 2241
            Y CK  N  GE  +   L V G R  + D      ++KI++        R +       P
Sbjct: 2866 YRCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKR--------RTDTMRLLERP 2916

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ---SAARFHITFDFG 2298
            P F   L   T  + G+   F   +  VH P   + +Y +G+ ++   +  ++    D G
Sbjct: 2917 PEFTLPLYNKT-AYVGENVRFGVTI-TVH-PEPHVTWYKSGQKIKPGDNDKKYTFESDKG 2973

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
               L I     +D  EY+V A N  G  +    +TVT        + RP
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 3022



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 80/334 (23%), Positives = 133/334 (39%), Gaps = 43/334 (12%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
            EG +V   C+++   DQ+ +V W+   + ++   ++   YE     L +  +   D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 1384 TCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIK 1443
             C+  N  GE  +   L V   ++ + +      ++KI+   DT R  +          +
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKRRTDTMRLLE----------R 2915

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P   T P   +    G++V F   +    + +  V W+K+GQ +  G      +D  Y  
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPH--VTWYKSGQKIKPGD-----NDKKYT- 2967

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
                     D G+Y    +N V TD+ +        T + R+   E   +    +     
Sbjct: 2968 ------FESDKGLYQL-TINSVTTDDDA------EYTVVARNKYGEDSCKAKLTVTLHPP 3014

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
               TD     +T  P+    L N E +EGQ   FE R+  +   TLK  W  + +PL  G
Sbjct: 3015 --PTD-----STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLG 3065

Query: 1624 SRFTETN-NFGFVALDIMSCLPEDSGTYTCRAIN 1656
                  +    + AL I   LPED+G Y   A N
Sbjct: 3066 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATN 3099



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 79/290 (27%), Positives = 112/290 (38%), Gaps = 26/290 (8%)

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG- 4539
            F    EN GG ++ S   + E    +    I  P F    +N+NV       L  KVTG 
Sbjct: 2124 FRVKCENLGGESEWSE--ISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGH 2181

Query: 4540 TKPIDVYWLKNGKKVQPD-IRNKILEEDGTYTLLILEAYPQDSGK-YECVAINSAGEARC 4597
             KPI V W + GK++  D ++ +I E  G Y  LI+ +   D    Y+  A N  G    
Sbjct: 2182 PKPI-VKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSG 2240

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             A   V +PA    PK            +E +       G+ +       GKP P + W 
Sbjct: 2241 TASLEVEVPAKIHLPK-----------TLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ 2289

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFP-EDEGDYKCVAYNSAGRVTVAAKLKVTQ-P 4715
            KG  LI  + ++Q+  T    +L        +D G Y   A N  G      +L V   P
Sbjct: 2290 KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVP 2349

Query: 4716 DQADNLPALTPLRDIV-VYEGQPA-----QFKTQITSKIKPTIQ-WLREG 4758
            D    +      RD V +   +PA     +    I  K   T + WLR G
Sbjct: 2350 DPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG 2399



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 54/219 (24%), Positives = 93/219 (42%), Gaps = 21/219 (9%)

Query: 3571 ENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLY 3630
            E     + C+ I   D S +V W+   + L    + +   + G  IL +  + + D G Y
Sbjct: 2808 EGGHVKYVCK-IENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 3631 TCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDE 3690
             CK  N +GE +   +L VKG + +        + +   + I++  +T+   E       
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREV-----YDYYCRRTMKKIKRRTDTMRLLE------- 2914

Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG--SRVHTL- 3747
               PP FT+ +  N     G  V F   +    +P   + W+ +G+    G   + +T  
Sbjct: 2915 --RPPEFTLPLY-NKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFE 2969

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +D G   L I+ +   D  EYT  A NK+G  +  AK+T
Sbjct: 2970 SDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLT 3008



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 35/146 (23%), Positives = 65/146 (44%), Gaps = 4/146 (2%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP   K  +D     G+  +  C++ GRP P++ W+   +++     +K + ++   H L
Sbjct: 1759 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYK-MSSDGRTHTL 1817

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             +      D GV TC+A N+ GE     +L +++      P +  +        G  + L
Sbjct: 1818 TVMTEEQEDEGVYTCIATNEVGEVETSSKL-LLQATPQFHPGYPLKEKYYGA-VGSTLRL 1875

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPE 536
            +   +G P P +TW   G  ++ N E
Sbjct: 1876 HVMYIGRPVPAMTW-FHGQKLLQNSE 1900



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 50/214 (23%), Positives = 94/214 (43%), Gaps = 21/214 (9%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V +EG ++ + C +E + D + ++ W+F  + L +  +Y+ T++     L +    + D 
Sbjct: 2805 VGEEGGHVKYVCKIE-NYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDD 2863

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
            G Y CK  N  G  ++   L   G + +Y    +   +   +   + +  RL +  RP  
Sbjct: 2864 GTYRCKVVNDYGEDSSYAELFVKGVREVY---DYYCRRTMKKIKRRTDTMRLLE--RP-- 2916

Query: 2904 PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQG---SRF 2960
                   PE+ +P+  +   V G+  ++   V     P+  + WY +G+ ++ G    ++
Sbjct: 2917 -------PEFTLPLYNKTAYV-GE--NVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKY 2966

Query: 2961 KLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
               SD G   L +  V   D   YT  A NK GE
Sbjct: 2967 TFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 3000



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 48/200 (24%), Positives = 80/200 (40%), Gaps = 3/200 (1%)

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMS 4672
            P++      P   E L++  V         CK+ G P P V+WY+ G ++I     +++ 
Sbjct: 2146 PKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQ 2205

Query: 4673 RTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
                 Y  L I+    +D   Y+  A N  G V+  A L+V  P +      L  +  + 
Sbjct: 2206 EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVH 2265

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE-EDTGT 4790
               G+    K   + K  P I W +   LI     +Q+I   +   L+  N  E +D G 
Sbjct: 2266 ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGF 2325

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            +   A    G  + + +L V
Sbjct: 2326 YVVCAKNRFGIDQKTVELDV 2345



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 50/196 (25%), Positives = 81/196 (41%), Gaps = 19/196 (9%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRAT 4051
            K+ C++    D + +V W+F  + L +  ++   Y+ G   +    +   D G Y C+  
Sbjct: 2813 KYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 2871

Query: 4052 NLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPP 4111
            N YG D + A +   G    VYD    + MK I++        +    +++E      PP
Sbjct: 2872 NDYGEDSSYAELFVKGVRE-VYDYYCRRTMKKIKR--------RTDTMRLLER-----PP 2917

Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR-YKLTYD---GMYHF 4167
             F       T   GE  RF   +T HP+P V W  +G  I  G    K T++   G+Y  
Sbjct: 2918 EFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQL 2977

Query: 4168 DIPKTRQYDTGKIEVI 4183
             I      D  +  V+
Sbjct: 2978 TINSVTTDDDAEYTVV 2993



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 28/92 (30%), Positives = 49/92 (53%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I ++ ++   + G  AQ   Q+ G P P + W++ G+ LI S K+++ +     TL V
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
               ++ D G YT +A N  G + TS  L +++
Sbjct: 1820 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 44/200 (22%), Positives = 81/200 (40%), Gaps = 15/200 (7%)

Query: 1606 DATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG 1665
            D + +V WY   + L++  ++  T   G   L +      D GTY C+ +N  GE  +  
Sbjct: 2822 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 2881

Query: 1666 IAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAEN 1725
               V   + +Y +      + ++ +  DT +         ++ + P FT+P+ +      
Sbjct: 2882 ELFVKGVREVY-DYYCRRTMKKIKRRTDTMR---------LLERPPEFTLPLYNKTAYVG 2931

Query: 1726 QAAHFEARLIPVGDPKLRVEWLRNGVPIEASN---RLTTMHDFGYVALNMKYVNPEDSGT 1782
            +   F   +     P+  V W ++G  I+  +   + T   D G   L +  V  +D   
Sbjct: 2932 ENVRFGVTI--TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAE 2989

Query: 1783 YTCRAINELGEAVTSSTLFV 1802
            YT  A N+ GE    + L V
Sbjct: 2990 YTVVARNKYGEDSCKAKLTV 3009



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 2/105 (1%)

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
            R    ++  +T  +AP   + + ++ T  G    L C++  VG     ++W+  GK +  
Sbjct: 1745 RTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQ 1802

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
              +++ + +     L +++   ED GVYTC ATN++GE  TS  L
Sbjct: 1803 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 4/85 (4%)

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
            TKL  G++A   C+I   P P+  ++WY  GK L    +Y+ S+D     L ++T   ED
Sbjct: 1771 TKL--GEAAQLSCQIVGRPLPD--IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQED 1826

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQS 1938
             G YTC A N +G+  +S +L +Q+
Sbjct: 1827 EGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 70/334 (20%), Positives = 131/334 (39%), Gaps = 44/334 (13%)

Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEY 2315
            EG    + C++E  +D + ++ +Y   + L+++ ++ IT++ G   L ++     D G Y
Sbjct: 2808 EGGHVKYVCKIEN-YDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 2316 SVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKI-RELESAEPFKRPEIPEPVTRQ 2374
              K +N  G  +S   + V     +     R   ++KI R  ++    +RP         
Sbjct: 2867 RCKVVNDYGEDSSYAELFVKGVREVYDYYCR-RTMKKIKRRTDTMRLLERP--------- 2916

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
             P FT PL N      G+   F   +    +P   V W+++ + I+      K + F   
Sbjct: 2917 -PEFTLPLYN-KTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDN-DKKYTF--- 2968

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494
                    + D+G+Y    +++  +              +    ++ E   K +     H
Sbjct: 2969 --------ESDKGLYQLTINSVTTDDDAEYT--------VVARNKYGEDSCKAKLTVTLH 3012

Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
                  P     +P+F ++L   +E  EGQ   +E RV  +  P+L+  W  +G  L +G
Sbjct: 3013 P----PPTDSTLRPMFKRLLAN-AECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLG 3065

Query: 2555 SRFRTTHD-FGFVTLDINSVVANDAGLYMCKAIN 2587
                  H+   +  L I   +  D G Y   A N
Sbjct: 3066 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATN 3099



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 53/204 (25%), Positives = 83/204 (40%), Gaps = 19/204 (9%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            D + +V WY+  + L+   ++    + G  IL +      D G Y C+  N+YGE  + A
Sbjct: 2822 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 2881

Query: 3509 SMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI 3568
             + V+G R +            T+ KI   +  + T+  L        PPEFT    +  
Sbjct: 2882 ELFVKGVREV-----YDYYCRRTMKKI---KRRTDTMRLLE------RPPEFTLPLYNKT 2927

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI---NDFGFVILEIGGVYQR 3625
                 +  F    I V+     V W+ +G+ +  G   K     +D G   L I  V   
Sbjct: 2928 AYVGENVRFGV-TITVHPEP-HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 2985

Query: 3626 DAGLYTCKATNRHGEATVSCKLQV 3649
            D   YT  A N++GE +   KL V
Sbjct: 2986 DDAEYTVVARNKYGEDSCKAKLTV 3009



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP     MKD+     +AA    ++  VG P   ++W R G  +  S +     D    
Sbjct: 1758 EAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH 1815

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L +     ED G YTC A NE+GE  TSS L +Q+
Sbjct: 1816 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 49/228 (21%), Positives = 89/228 (39%), Gaps = 15/228 (6%)

Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448
            +EG    + C+ I   D + +V W+   + +E+S +   T++ G   + +  +   D+G 
Sbjct: 2807 EEGGHVKYVCK-IENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGT 2865

Query: 2449 YMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKP 2508
            Y C+  N  GE              +  +      MKKI++  +    R  E   EF  P
Sbjct: 2866 YRCKVVNDYGEDSSYAELFVKGVREV-YDYYCRRTMKKIKR--RTDTMRLLERPPEFTLP 2922

Query: 2509 IFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG---SRFRTTHDFGF 2565
            ++ +        + G++  +   +    +P +   WY +G ++K G    ++    D G 
Sbjct: 2923 LYNKT------AYVGENVRFGVTITVHPEPHV--TWYKSGQKIKPGDNDKKYTFESDKGL 2974

Query: 2566 VTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRP 2613
              L INSV  +D   Y   A N+ G                 D  +RP
Sbjct: 2975 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRP 3022



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 47/208 (22%), Positives = 83/208 (39%), Gaps = 27/208 (12%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL---INSNKHEIITTHNHT 321
            PP+      N     G + +F V ++ +P P VTW+K+GQ++    N  K+   +     
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 2975

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
             L + +    D   YT++A N                   Y +D     +T T       
Sbjct: 2976 QLTINSVTTDDDAEYTVVARN------------------KYGEDSCKAKLTVTLHPPP-- 3015

Query: 382  RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
                ++  L P F ++  + +  EG+   F+ RV+G P P + W  + + +    N +I+
Sbjct: 3016 ----TDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII 3071

Query: 442  VNESGNHALMITNVTLSDSGVVTCVARN 469
                  +AL I +    D+G     A N
Sbjct: 3072 HEGLDYYALHIRDTLPEDTGYYRVTATN 3099



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 49/204 (24%), Positives = 84/204 (41%), Gaps = 12/204 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P   K+M+       E A+   +  G PLP IKWYR    +  S  +++ +      L +
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                 ED  V+  +A N  G  + S+ L+++   +        P + L  +      G  
Sbjct: 1820 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ------FHPGYPLKEKYYGAV-GST 1872

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ--DSGKYECVA 4588
            +RL     G +P+      +G+K+  +  N  +E    YT L+++   +   +GKY+   
Sbjct: 1873 LRLHVMYIG-RPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQL 1931

Query: 4589 INSAGEARCDAECVVSLPATKDKP 4612
             N  G    DA   V +    DKP
Sbjct: 1932 SNVFGTV--DAILDVEIQDKPDKP 1953



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 2/74 (2%)

Query: 2926 GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
            G+   L  Q+  +  PD+K  WY  GK L Q  ++K++SD    TL ++   + D G+YT
Sbjct: 1774 GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 2986 CKAYNKRGEAFTSS 2999
            C A N+ GE  TSS
Sbjct: 1832 CIATNEVGEVETSS 1845



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 53/216 (24%), Positives = 83/216 (38%), Gaps = 17/216 (7%)

Query: 650  EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEY 709
            EGG + +  +IE   D + ++ W    + +E S ++   +  G   L +  +   D G Y
Sbjct: 2808 EGGHVKYVCKIENY-DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 2866

Query: 710  TCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQR 769
             C+ V+  G   + A L V             E   Y  +     K + +        + 
Sbjct: 2867 RCKVVNDYGEDSSYAELFV---------KGVREVYDYYCR-RTMKKIKRRTDTMRLLERP 2916

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDG---RPITASSRITSIFNFG 826
            P+F  PL +      G N  F   +T   +P   V WYK G   +P     + T   + G
Sbjct: 2917 PEFTLPLYN-KTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 2973

Query: 827  YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               L I  +  +D   YTV A NK GE    A + V
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 3009



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 3/95 (3%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            S E P    +++DVT  + G++A    ++V    PD+K  W+  GK+L    +Y+   D 
Sbjct: 1756 SGEAPGIRKEMKDVTTKL-GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDG 1812

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
                L ++   +E+ G Y C+ATN++G   T + L
Sbjct: 1813 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 25/89 (28%), Positives = 41/89 (46%)

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
            AP   +    +  + GE   L+ + VG P P I W + G  +I + + ++ +DG   TL 
Sbjct: 1759 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 1818

Query: 550  IPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +   +  D   Y C A N  G   T ++L
Sbjct: 1819 VMTEEQEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P   K +K+     G    L   +  V  P   ++WY  G+ + Q  ++K + D    
Sbjct: 1758 EAPGIRKEMKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTH 1815

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
             L ++    ED G Y C ATN VGE  T+S + + A
Sbjct: 1816 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 30/82 (36%), Positives = 44/82 (53%), Gaps = 4/82 (4%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF-NFGY 827
            RP F R L +  E QEG++  FE +++ +  PT++  W KDG+P++    I  I     Y
Sbjct: 3021 RPMFKRLLAN-AECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDY 3077

Query: 828  VSLNIMHLRAEDAGSYTVRAVN 849
             +L+I     ED G Y V A N
Sbjct: 3078 YALHIRDTLPEDTGYYRVTATN 3099



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 2/69 (2%)

Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
           ++ GA  +  V +SG P P +TW K G  L  +++  I TT +++ L V    + D+G Y
Sbjct: 685 IRAGASLRLMVSVSGRPPPVITWSKQGIDL--ASRAIIDTTESYSLLIVDKVNRYDAGKY 742

Query: 337 TLLAENPNG 345
           T+ AEN +G
Sbjct: 743 TIEAENQSG 751



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 6/106 (5%)

Query: 3544 TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLI--PVNDSSMRVEWFHNGKPLL 3601
            T  ++  +  SG  P       D+      +A   C+++  P+ D    ++W+  GK L+
Sbjct: 1746 TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD----IKWYRFGKELI 1801

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
               + K  +D     L +    Q D G+YTC ATN  GE   S KL
Sbjct: 1802 QSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            + ++  K G+     C +     P +K  W+   K L    +YK + D    +L +    
Sbjct: 1766 MKDVTTKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEE 1823

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
            +ED G+YTC ATN  G   TS  L
Sbjct: 1824 QEDEGVYTCIATNEVGEVETSSKL 1847



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   L  Q+  R  P++K  W++ G  L    + K + D    TL++ +   +D G+YT
Sbjct: 1774 GEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 2717 CKATNLLGEAVSTASIKIE 2735
            C ATN +GE  +++ + ++
Sbjct: 1832 CIATNEVGEVETSSKLLLQ 1850



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P    ++K  T +  E  +  C++  +  P   I+WYR GK L    +Y+   D    +L
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD--IKWYRFGKELIQSRKYKMSSDGRTHTL 1817

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             ++    ED G Y C A N+ GE  T + +  +  P
Sbjct: 1818 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATP 1853



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 4407 PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP-IKNSPDFQIHTF-ST 4464
            P + P F ++++   V     A    +  G P P++KWYR+    I +   ++I  F   
Sbjct: 2151 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 2210

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
               LII  V  +D+ V+   A N+GG+   +A+L VE
Sbjct: 2211 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 2247



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 5/103 (4%)

Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP-IKTGHRFR 1360
            + D+ + QAP F   L N+     +N  L C++   G     V+W+  GK  I  G ++R
Sbjct: 2147 KSDVPI-QAPHFKEELRNLNVRYQSNATLVCKV--TGHPKPIVKWYRQGKEIIADGLKYR 2203

Query: 1361 -PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
               ++  Y  L + SV  +D+ VY  +ATNQ G    + +L V
Sbjct: 2204 IQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 2246



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 32/93 (34%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHT-DGGA 545
            + AP F E    LNVR      L  +  G P P + W + G  II +  + RI    GG 
Sbjct: 2152 IQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGY 2211

Query: 546  STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              L I      DA  YQ  A N  GS +  A L
Sbjct: 2212 HQLIIASVTDDDATVYQVRATNQGGSVSGTASL 2244



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
           ++ G+D      + G P P++ W K  + L    K  +  T    T  ++   +SDSG Y
Sbjct: 286 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKY 345

Query: 337 TLLAENPNGCIVTSGYLAV-ESP 358
           TL  +N +G    S  + V +SP
Sbjct: 346 TLTVKNASGTKAVSVMVKVLDSP 368



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            +++G   +  + + G P P   W K GQ +  S +  I T+  HT L ++   + DSG Y
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTY 1432

Query: 337  TLLAENPNG 345
             L+ EN  G
Sbjct: 1433 DLVLENKCG 1441



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P   +  K+     G  A+   ++ G P P + W R    L++  KY M  + +T  +++
Sbjct: 1760 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 1819

Query: 132  LIKQIGPGDEGEYTCTARNQYGE 154
            + ++    DEG YTC A N+ GE
Sbjct: 1820 MTEE--QEDEGVYTCIATNEVGE 1840



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 2/69 (2%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G+ A   C++  VG P   ++W+R  K +  S +   + D    ++T+     EDEGVY 
Sbjct: 1774 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 2451 CRASNLLGE 2459
            C A+N +GE
Sbjct: 1832 CIATNEVGE 1840



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 3/68 (4%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH-EIITTHNHTTLRVRN-TQKSDSGHYT 337
            G     ++  SG P P +TW K GQ LI++N H ++I T + T+L   N  ++ D+G Y 
Sbjct: 2269 GEVVSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYV 2327

Query: 338  LLAENPNG 345
            + A+N  G
Sbjct: 2328 VCAKNRFG 2335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 3/89 (3%)

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
            + G+ P     ++++   K G++A   C +V    PD+K  WY  G+ +  S + K  SD
Sbjct: 1755 TSGEAPGIRKEMKDVT-TKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSRKYKMSSD 1811

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                 L +   +  D G Y C A N+ GE
Sbjct: 1812 GRTHTLTVMTEEQEDEGVYTCIATNEVGE 1840



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 2122 KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
            K G+ A   C++  +  P   I W+  G+++    +Y+ + D     L ++    ED G 
Sbjct: 1772 KLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 1829

Query: 2182 YMCKATNKLGEAVNTCTL 2199
            Y C ATN++GE   +  L
Sbjct: 1830 YTCIATNEVGEVETSSKL 1847



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 6/91 (6%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLI--PVSDATLKVEWYHNNKPLKSGSRFTETNNFG 1633
            +AP     +K+V  K G+ A    +++  P+ D    ++WY   K L    ++  +++  
Sbjct: 1758 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPD----IKWYRFGKELIQSRKYKMSSDGR 1813

Query: 1634 FVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
               L +M+   ED G YTC A N +GE  TS
Sbjct: 1814 THTLTVMTEEQEDEGVYTCIATNEVGEVETS 1844



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 4/122 (3%)

Query: 246  GESD-VQISTEID-RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
            GES+  +IS  I  +S  P+  P   ++ RN  ++  ++A    +++G+P+P V W++ G
Sbjct: 2133 GESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQG 2192

Query: 304  QRLI-NSNKHEIIT-THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTES 361
            + +I +  K+ I      +  L + +    D+  Y + A N  G +  +  L VE P + 
Sbjct: 2193 KEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKI 2252

Query: 362  YV 363
            ++
Sbjct: 2253 HL 2254



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSI---EASSRFTSIFRFG 692
            PP+F +PL + TA  G  + F   I    +P   + W K+GQ I   +   ++T     G
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEP--HVTWYKSGQKIKPGDNDKKYTFESDKG 2973

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
               L + S+   D  EYT  A +  G    KA L VT
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 3010



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR---KKAPLVECNKYSMRYNEQTG 127
            PP F     N     G N +F   +  +P P V+W +   K  P     KY+  +    G
Sbjct: 2916 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT--FESDKG 2973

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
               L I  +   D+ EYT  ARN+YGE  C
Sbjct: 2974 LYQLTINSVTTDDDAEYTVVARNKYGEDSC 3003



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 12/133 (9%)

Query: 2366 EIPEPVTR------QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI 2419
            EI EP+T       Q P F + L+N+ N++    A   C++   G P   V+W+R  K I
Sbjct: 2139 EISEPITPKSDVPIQAPHFKEELRNL-NVRYQSNATLVCKV--TGHPKPIVKWYRQGKEI 2195

Query: 2420 EDSSRITKTHDF--GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE 2477
                   +  +F  GY  + I+ V D+D  VY  RA+N  G               I L 
Sbjct: 2196 IADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL- 2254

Query: 2478 TQHPEGMKKIQKL 2490
             +  EGM  +  L
Sbjct: 2255 PKTLEGMGAVHAL 2267



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 768  QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-- 825
            Q P F   L++L    +  NA    ++T    P   V+WY+ G+ I A      I  F  
Sbjct: 2153 QAPHFKEELRNLNVRYQS-NATLVCKVT--GHPKPIVKWYRQGKEIIADGLKYRIQEFKG 2209

Query: 826  GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            GY  L I  +  +DA  Y VRA N+ G    TAS+ V
Sbjct: 2210 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 2246



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTG 4178
            VT + GE A+  C++ G P P + W   G  ++   +YK++ DG  H   +    Q D G
Sbjct: 1769 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEG 1828



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-FG 1766
            T  P+F   + +    E Q+  FE R+  +  P L+  W ++G P+     +  +H+   
Sbjct: 3019 TLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLD 3076

Query: 1767 YVALNMKYVNPEDSGTYTCRAIN 1789
            Y AL+++   PED+G Y   A N
Sbjct: 3077 YYALHIRDTLPEDTGYYRVTATN 3099



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 4/110 (3%)

Query: 1703 QDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
            + +V  QAP F   ++++ V     A    ++   G PK  V+W R G  I A      +
Sbjct: 2147 KSDVPIQAPHFKEELRNLNVRYQSNATLVCKV--TGHPKPIVKWYRQGKEIIADGLKYRI 2204

Query: 1763 HDF--GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             +F  GY  L +  V  +D+  Y  RA N+ G    +++L V+  A + L
Sbjct: 2205 QEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL 2254



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G +   +  + G P P + WT+    L  C K S++Y  +    + +IK     D G+YT
Sbjct: 289 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKR--ATAVIKFCDRSDSGKYT 346

Query: 146 CTARNQYGEAICSVYIQ 162
            T +N  G    SV ++
Sbjct: 347 LTVKNASGTKAVSVMVK 363



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 33/106 (31%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
           S+Y     + E  ERIEI +  LA    K    R    G   R    V+GRP P +TW  
Sbjct: 653 SEYSESIAEIEPVERIEIPDLELADDLKKTVTIR---AGASLRLMVSVSGRPPPVITW-- 707

Query: 428 NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
             +Q  D  +  I+        L++  V   D+G  T  A N+SG+
Sbjct: 708 -SKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGK 752



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 20/66 (30%), Positives = 31/66 (46%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
            G   +  + ++G P P  +WF  G +L  S +  + T      L +R T   D+G YTL 
Sbjct: 980  GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 1039

Query: 340  AENPNG 345
             +N  G
Sbjct: 1040 LKNVTG 1045



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 48/184 (26%), Positives = 80/184 (43%), Gaps = 10/184 (5%)

Query: 3774 NKWGSATTTA-KITCSAKRDIVLESQLPQGMSGEKIK-ELERGRISD--APKEEPIVSTP 3829
            NKW S TT   + T  + ++++   +    +  E +  E E   IS+   PK +  +  P
Sbjct: 2096 NKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAP 2155

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYR-TVYDMGFV 3887
              F  ++++  V         C+V     PK  ++WYR GK ++  G +YR   +  G+ 
Sbjct: 2156 -HFKEELRNLNVRYQSNATLVCKVTGH--PKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 2212

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQME 3947
             L I  V  +D+  Y  RA N  G     A++   ++P  I   +   GM    AL    
Sbjct: 2213 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTLEGMGAVHALRGEV 2271

Query: 3948 ATIK 3951
             +IK
Sbjct: 2272 VSIK 2275



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 4091 EASWQVTPEQVVEESKARCP-PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            E+ W    E +  +S      P F      + V     A   C+VTGHPKP V W   G 
Sbjct: 2134 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 2193

Query: 4150 TIV-NGSRYKL-TYDGMYH 4166
             I+ +G +Y++  + G YH
Sbjct: 2194 EIIADGLKYRIQEFKGGYH 2212



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)

Query: 3403 SMVRRKDTSVEEE--KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
            S  RR   S++ +   G+AP     + ++   + GE A    ++     P++K  WY  G
Sbjct: 1741 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTT-KLGEAAQLSCQIVGRPLPDIK--WYRFG 1797

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            K L    +++   D     L +     ED G Y C A N  GE  T++ + +Q
Sbjct: 1798 KELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 1850



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/60 (28%), Positives = 32/60 (53%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            ++WY  GK++  + + +   D     L + +   ED GVYT +A N  GE + S+ + ++
Sbjct: 1791 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 1850



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 2/79 (2%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V +G  I  +  I GKP P  +W K  + I        S T  E  L I EA   D G Y
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTE--LVIKEADRGDSGTY 1432

Query: 4694 KCVAYNSAGRVTVAAKLKV 4712
              V  N  G+  V  K++V
Sbjct: 1433 DLVLENKCGKKAVYIKVRV 1451



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/190 (21%), Positives = 75/190 (39%), Gaps = 11/190 (5%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            +G  P      KD+     G+ A     ++  G     I+W+  GK +  S + +     
Sbjct: 1756 SGEAPGIRKEMKDVTT-KLGEAAQLSCQIV--GRPLPDIKWYRFGKELIQSRKYKMSSDG 1812

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L ++  +  D G Y+C ATN+ G+ E S KL          P+F       E    
Sbjct: 1813 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL-----LLQATPQFHPGYPLKEKYYG 1867

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQNHDSGE 3221
               +     V+ +  P   + W+H  + +++S    I+    +  +V+     + H +G+
Sbjct: 1868 AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTH-AGK 1926

Query: 3222 YVCRAYNKYG 3231
            Y  +  N +G
Sbjct: 1927 YKVQLSNVFG 1936



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 3/70 (4%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLI-NSNKHEIITTHNHTTLRVRNTQ-KSDSGHYT 337
            G+  +  V   G P P +TWF +GQ+L+ NS    I  T ++T L ++N Q K+ +G Y 
Sbjct: 1870 GSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYK 1928

Query: 338  LLAENPNGCI 347
            +   N  G +
Sbjct: 1929 VQLSNVFGTV 1938



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/164 (24%), Positives = 67/164 (40%), Gaps = 10/164 (6%)

Query: 3075 TGDQSMVIEWFYNGKTIEA---SHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            TG    +++W+  GK I A    +RI+  +  G   L I      D+  Y  RATN+ G 
Sbjct: 2179 TGHPKPIVKWYRQGKEIIADGLKYRIQE-FKGGYHQLIIASVTDDDATVYQVRATNQGGS 2237

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD-DPDMKIEWYHNGQ 3190
               +  LE    +K   P+    +  +  L+ G+    +   +P    PD  I W     
Sbjct: 2238 VSGTASLEVEVPAKIHLPKTLEGMGAVHALR-GEVVSIK---IPFSGKPDPVITWQKGQD 2293

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAY-TQNHDSGEYVCRAYNKYGED 3233
             + ++   + +    F  L      +  D+G YV  A N++G D
Sbjct: 2294 LIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGID 2337



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 1/85 (1%)

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTF 4462
            P   +  P+F + +      E +   FE+   G P P +KW ++  P+   P+ + IH  
Sbjct: 3015 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEG 3074

Query: 4463 STKSILIIRQVFVEDSAVFAAVAEN 4487
                 L IR    ED+  +   A N
Sbjct: 3075 LDYYALHIRDTLPEDTGYYRVTATN 3099



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 1459 GQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGI 1516
            G+     C++   P+ D    ++W++ G+ +    +++   D     L ++    ED G+
Sbjct: 1774 GEAAQLSCQIVGRPLPD----IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 1829

Query: 1517 YTCRAVNLVGTDEVSCRLTCRST 1539
            YTC A N VG  E S +L  ++T
Sbjct: 1830 YTCIATNEVGEVETSSKLLLQAT 1852



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 21/74 (28%), Positives = 35/74 (47%)

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
           + +R G  +VL+A   G P P+I W K    +    ++ +   G  +T  I     SD+ 
Sbjct: 284 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 343

Query: 560 WYQCTAQNVAGSTA 573
            Y  T +N +G+ A
Sbjct: 344 KYTLTVKNASGTKA 357



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 3/95 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P    E+KD +    G      C++  VG P   I W+  G+      +    +D     
Sbjct: 1760 PGIRKEMKD-VTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT 1816

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
            L +      D G YTC ATN+ G   T++K+   A
Sbjct: 1817 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 1851



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 3/72 (4%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGFIALDIDYIYA 3762
            N +  EG  V F+ RV  +  PT++  W  +G+P + G  +  +++   + AL I     
Sbjct: 3030 NAECQEGQSVCFEIRVSGIPPPTLK--WEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLP 3087

Query: 3763 RDAGEYTCRATN 3774
             D G Y   ATN
Sbjct: 3088 EDTGYYRVTATN 3099



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 21/79 (26%), Positives = 32/79 (40%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            +  G  +     + GKP P + W KGDK +   +   +  T    T  I      D G Y
Sbjct: 286  IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKY 345

Query: 4694 KCVAYNSAGRVTVAAKLKV 4712
                 N++G   V+  +KV
Sbjct: 346  TLTVKNASGTKAVSVMVKV 364



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 8/116 (6%)

Query: 48  MTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR 107
           M+   ES  + +P+   R   P   + + + K      G + +    + G P PV++W++
Sbjct: 652 MSEYSESIAEIEPVE--RIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK 709

Query: 108 KKAPLVECNKYSMRYNEQTGDVSLLI-KQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           +   L      S    + T   SLLI  ++   D G+YT  A NQ G+   +V ++
Sbjct: 710 QGIDLA-----SRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 760



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 40/159 (25%), Positives = 55/159 (34%), Gaps = 5/159 (3%)

Query: 3629 LYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE 3688
            L  CKA        V+ K  V       L       F+   ++ + + E       +T++
Sbjct: 898  LEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQ 957

Query: 3689 DEKPNPP-RFTVEIKDNIDVPEGGPVHFDCRVEPV-GDPTMRIDWFHNGRPFATGSRVHT 3746
            D +  P    +   +  I VP G PV     V P+ G P     WF  G       RV  
Sbjct: 958  DLRVLPTIDLSTMPQKTIHVPAGRPVEL---VIPIAGRPPPAASWFFAGSKLRESERVTV 1014

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                    L I     RD GEYT    N  G+   T K+
Sbjct: 1015 ETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTLETIKV 1053



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 2/107 (1%)

Query: 59   QPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK-KAPLVECNK 117
            +PIT         P F++  +N       NA    K+ G+P P+V W R+ K  + +  K
Sbjct: 2142 EPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 2201

Query: 118  YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            Y ++   + G   L+I  +   D   Y   A NQ G    +  ++ E
Sbjct: 2202 YRIQ-EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 2247



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRG-NPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P+  QI  +A   +GG+ K+  K+   + +  V+W      L    KY + Y +  G   
Sbjct: 2796 PVSGQIM-HAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED--GVAI 2852

Query: 131  LLIKQIGPGDEGEYTCTARNQYGE 154
            L +K I   D+G Y C   N YGE
Sbjct: 2853 LYVKDITKLDDGTYRCKVVNDYGE 2876



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 1/79 (1%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F+++  NA   +G +  FE ++ G P P + W +   PL       +  +E     +L
Sbjct: 3022 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEI-IHEGLDYYAL 3080

Query: 132  LIKQIGPGDEGEYTCTARN 150
             I+   P D G Y  TA N
Sbjct: 3081 HIRDTLPEDTGYYRVTATN 3099



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNK 470
           D  V G+P P++ W   D+++  D   K+ +  +G  A  +I     SDSG  T   +N 
Sbjct: 295 DAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 352

Query: 471 SGETAFQCRLNVIE 484
           SG  A    + V++
Sbjct: 353 SGTKAVSVMVKVLD 366



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 2648 LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSL 2707
            LK    +  G  + L   V  R  P   I W K G+ L + A + +T  + L  L ++ +
Sbjct: 679  LKKTVTIRAGASLRLMVSVSGRPPP--VITWSKQGIDLASRAIIDTTESYSL--LIVDKV 734

Query: 2708 RNDDSGIYTCKATNLLGEAVSTASIKIED 2736
               D+G YT +A N  G+  +T  +K+ D
Sbjct: 735  NRYDAGKYTIEAENQSGKKSATVLVKVYD 763



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            +K VT   G       +I  VG P   I+W + G+ +  S ++         +L +++  
Sbjct: 1766 MKDVTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEE 1823

Query: 703  IQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
             +D G YTC A +  G  ET  K +L  TP+
Sbjct: 1824 QEDEGVYTCIATNEVGEVETSSKLLLQATPQ 1854



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 785  GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
            G  A    Q+  V  P   ++WY+ G+ +  S +     +    +L +M    ED G YT
Sbjct: 1774 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 845  VRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRY 880
              A N++GE + T+S ++  ++T     G P + +Y
Sbjct: 1832 CIATNEVGE-VETSS-KLLLQATPQFHPGYPLKEKY 1865



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 11/120 (9%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT-GARLK-STFDF 2697
            QAP F   L++ +   +  +  L  +V     P +K  W++ G  +   G + +   F  
Sbjct: 2153 QAPHFKEELRNLNVRYQS-NATLVCKVTGHPKPIVK--WYRQGKEIIADGLKYRIQEFKG 2209

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLH-PDSLDRIGAL 2756
            G   L I S+ +DD+ +Y  +ATN  G    TAS+++E     +   +H P +L+ +GA+
Sbjct: 2210 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-----VPAKIHLPKTLEGMGAV 2264



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 3/67 (4%)

Query: 1057 EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD-FGYVALDIASVRAEDSGV 1115
            EGQS  FE RV      T+  +W  +G+ ++    I+  H+   Y AL I     ED+G 
Sbjct: 3035 EGQSVCFEIRVSGIPPPTL--KWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGY 3092

Query: 1116 YTVVARN 1122
            Y V A N
Sbjct: 3093 YRVTATN 3099



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 6/78 (7%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            QGG  +    ++G P P+  WT++     + +K +M    +T    L+IK+   GD G Y
Sbjct: 1377 QGGVIRLTIPIKGKPFPICKWTKEGQ---DISKRAMIATSET-HTELVIKEADRGDSGTY 1432

Query: 145  TCTARNQYGEAICSVYIQ 162
                 N+ G+   +VYI+
Sbjct: 1433 DLVLENKCGKK--AVYIK 1448



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 2/81 (2%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            E  +  CQ+  VG P   ++W+  GK L+   ++    D     +       ED G Y C
Sbjct: 1775 EAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC 1832

Query: 4049 RATNLYGMDETKAVIKTTGKP 4069
             ATN  G  ET + +     P
Sbjct: 1833 IATNEVGEVETSSKLLLQATP 1853



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 2/72 (2%)

Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           T+ +R G  + L     G P P ITW K G+ +       I T    S L + +    DA
Sbjct: 682 TVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLA--SRAIIDTTESYSLLIVDKVNRYDA 739

Query: 559 AWYQCTAQNVAG 570
             Y   A+N +G
Sbjct: 740 GKYTIEAENQSG 751



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 3/97 (3%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            S + P  +  +KD ++ K G  A    ++  +G     ++W + G+ +  S +     + 
Sbjct: 1756 SGEAPGIRKEMKD-VTTKLGEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDG 1812

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                LT+ +    D G YTC A N +G+  TS+ L +
Sbjct: 1813 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLL 1849



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+   L C++  +G P   ++W+  G+ +    ++K   D     L ++     D G YT
Sbjct: 1774 GEAAQLSCQI--VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYT 1831

Query: 1252 VRAVNHLGSAHTSA 1265
              A N +G   TS+
Sbjct: 1832 CIATNEVGEVETSS 1845



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 41/163 (25%), Positives = 65/163 (39%), Gaps = 10/163 (6%)

Query: 4357 GKEVHVAKQKQTQKEVVGDKE--ITRKITSTETTEIEHKAQTQERVVEGPVK-----PSK 4409
            GKE+     K   +E  G     I   +T  + T  + +A  Q   V G        P+K
Sbjct: 2192 GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 2251

Query: 4410 P--PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTFSTKS 4466
               P   + M        E    ++ F G+P P+I W +    I N+  +Q I T S  S
Sbjct: 2252 IHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTS 2311

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
            ++    V  +D+  +   A+NR G  + +  L V +     RG
Sbjct: 2312 LVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG 2354



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ- 4579
            + V + +G  +RL   V+G  P  + W K G  +       I++   +Y+LLI++   + 
Sbjct: 681  KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL---ASRAIIDTTESYSLLIVDKVNRY 737

Query: 4580 DSGKYECVAINSAGE 4594
            D+GKY   A N +G+
Sbjct: 738  DAGKYTIEAENQSGK 752



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
            V  G+       + GRP P  +WF    ++R+  + ++ V      A L I   T+ D+G
Sbjct: 977  VPAGRPVELVIPIAGRPPPAASWFFAGSKLRE--SERVTVETHTKVAKLTIRETTIRDTG 1034

Query: 462  VVTCVARNKSGETAFQCRLNVIEK 485
              T   +N +G T    ++ +++K
Sbjct: 1035 EYTLELKNVTGTTLETIKVIILDK 1058



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/60 (28%), Positives = 25/60 (41%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            W   G  +  S R+T   +     LTI+  T+ D G YT    N  G    +  + I+ K
Sbjct: 999  WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTLETIKVIILDK 1058



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSG 461
            V +G + R    + G+P+P   W    +    D + + ++  S  H  L+I      DSG
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQ----DISKRAMIATSETHTELVIKEADRGDSG 1430

Query: 462  VVTCVARNKSGETAFQCRLNVI 483
                V  NK G+ A   ++ VI
Sbjct: 1431 TYDLVLENKCGKKAVYIKVRVI 1452



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
            R  +   G+P P+ KW +E   I  S    I T  T + L+I++    DS  +  V EN+
Sbjct: 1382 RLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENK 1439

Query: 4489 GG 4490
             G
Sbjct: 1440 CG 1441



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHV-RDEDEGVYMCRASNLLG 2458
            +G P   + WF  +KL+++S  IT  +   Y  + + +V R    G Y  + SN+ G
Sbjct: 1880 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG 1936



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/74 (27%), Positives = 30/74 (40%)

Query: 499  TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
            T++V  G PV L     G P P  +W   G  +  +  + + T    + L I      D 
Sbjct: 974  TIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 1033

Query: 559  AWYQCTAQNVAGST 572
              Y    +NV G+T
Sbjct: 1034 GEYTLELKNVTGTT 1047



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/56 (32%), Positives = 26/56 (46%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            VG P    +WY  G EL    +++ + D    TL + +    D G+Y C A N  G
Sbjct: 1784 VGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 1839



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 9/114 (7%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PK +  + +      E V  +     K DP   I W +   L+ +   Y+ +    F SL
Sbjct: 2255 PKTLEGMGAVHALRGEVVSIKIPFSGKPDPV--ITWQKGQDLIDNNGHYQVIVTRSFTSL 2312

Query: 3890 DILY-VYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEA 3942
                 V  +D+G Y+  A N FG D     +    +PD       PRG+K S+A
Sbjct: 2313 VFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPD------PPRGVKVSDA 2360


>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase protein.
          Length = 1463

 Score =  107 bits (258), Expect = 7e-22
 Identities = 107/404 (26%), Positives = 164/404 (40%), Gaps = 44/404 (10%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P  T + Q   V       F    +G P P I W   N  +    D +++ F   + L+I
Sbjct: 234  PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGT-LMI 292

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP--PSFTLTAQNVNVTSG 4528
            R     D  V+  +A N  G AK  + ++        R   +P  PSF +  Q+  V  G
Sbjct: 293  RNTRESDQGVYQCMARNSAGEAKTQSAML--------RYSSLPAKPSFVIQPQDTEVLIG 344

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
                L+   TG     + W ++   ++ D    +    G Y   I +   +D G++ C A
Sbjct: 345  TSTTLECMATGHPHPLITWTRDNG-LELDGSRHVATSSGLYLQNITQ---RDHGRFTCHA 400

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             NS G  +  A  +V                 APP+     KD++V E  A+E+ C+  G
Sbjct: 401  NNSHGTVQAAANIIVQ----------------APPQFTVTPKDQVVLEEHAVEWLCEADG 444

Query: 4649 KPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             P P + W K G +L    ++  +S      TLRI  A   D+G Y+C A +S G   V+
Sbjct: 445  NPPPVIVWTKTGGQLPVEGQHTVLS----SGTLRIDRAAQHDQGQYECQAVSSLGVKKVS 500

Query: 4708 AKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
             +L V    +   L   T L +D  V  G+          + +P I W +EG  I E+  
Sbjct: 501  VQLTV----KPKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGK 556

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            F +  EG    L I +    D G + C A  + G   T+  L V
Sbjct: 557  FHVDDEG---TLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTV 597



 Score =  104 bits (249), Expect = 9e-21
 Identities = 94/321 (29%), Positives = 134/321 (41%), Gaps = 35/321 (10%)

Query: 4393 KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK 4452
            +A+TQ  ++     P+KP  F  + Q   V        E    G P PLI W R+N    
Sbjct: 313  EAKTQSAMLRYSSLPAKPS-FVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDN---G 368

Query: 4453 NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
               D   H  +T S L ++ +   D   F   A N  GT + +AN++V+           
Sbjct: 369  LELDGSRHV-ATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQ----------A 417

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP FT+T ++  V     V    +  G  P  + W K G ++  + ++ +L      TL 
Sbjct: 418  PPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSG---TLR 474

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            I  A   D G+YEC A++S G  +   +  V       KPK        P       +D 
Sbjct: 475  IDRAAQHDQGQYECQAVSSLGVKKVSVQLTV-------KPKALAVFTQLP-------QDT 520

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
             V  G+ I  SC   G+P P + W K    I  S  F +    DE TL I +A   D+G 
Sbjct: 521  SVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVD---DEGTLTIYDAGFPDQGR 577

Query: 4693 YKCVAYNSAGRVTVAAKLKVT 4713
            Y+CVA NS G       L VT
Sbjct: 578  YECVARNSFGLAVTNMFLTVT 598



 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 85/305 (27%), Positives = 134/305 (43%), Gaps = 35/305 (11%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTYTL 4571
            P  T   Q+V V SG  V    +  G    ++ W+ N   +  + D R  + + DGT  L
Sbjct: 234  PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFD-DGT--L 290

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECV--VSLPATKDKPKPQTKAANAPPEIIEPL 4629
            +I      D G Y+C+A NSAGEA+  +  +   SLPA              P  +I+P 
Sbjct: 291  MIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPA-------------KPSFVIQP- 336

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL-IKPSKYFQMSRTADEYTLRISEAFPE 4688
            +D  V  G +    C   G P P + W + + L +  S++  ++ ++  Y   I++    
Sbjct: 337  QDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRH--VATSSGLYLQNITQ---R 391

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            D G + C A NS G V  AA + V  P Q      +TP +D VV E    ++  +     
Sbjct: 392  DHGRFTCHANNSHGTVQAAANIIVQAPPQF----TVTP-KDQVVLEEHAVEWLCEADGNP 446

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             P I W + G  +P      ++  G    L I    + D G + C+A ++ G  + S +L
Sbjct: 447  PPVIVWTKTGGQLPVEGQHTVLSSG---TLRIDRAAQHDQGQYECQAVSSLGVKKVSVQL 503

Query: 4809 VVKSK 4813
             VK K
Sbjct: 504  TVKPK 508



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 86/305 (28%), Positives = 122/305 (40%), Gaps = 43/305 (14%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+I  +P++ ++  G    F  +  GNP+P + W  N   L +      +   +  TL +
Sbjct: 234 PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSL-DLEDDTRLNVFDDGTLMI 292

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
           RNT++SD G Y  +A N  G          E+ T+S +                   +  
Sbjct: 293 RNTRESDQGVYQCMARNSAG----------EAKTQSAM-------------------LRY 323

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
           S     P FV   QD +V  G  T  +C  TG P+P +TW  ++    D   H  +   S
Sbjct: 324 SSLPAKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRH--VATSS 381

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
           G   L + N+T  D G  TC A N  G    Q   N+I +     P+F        V E 
Sbjct: 382 G---LYLQNITQRDHGRFTCHANNSHG--TVQAAANIIVQ---APPQFTVTPKDQVVLEE 433

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             V     A G P P I W K G  +   P    HT   + TL I RA   D   Y+C A
Sbjct: 434 HAVEWLCEADGNPPPVIVWTKTGGQL---PVEGQHTVLSSGTLRIDRAAQHDQGQYECQA 490

Query: 566 QNVAG 570
            +  G
Sbjct: 491 VSSLG 495



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 55/189 (29%), Positives = 80/189 (42%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           +P+     QD +V  G    F CR  G P PE+ W  N+  +  + + ++ V + G   L
Sbjct: 233 SPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDG--TL 290

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           MI N   SD GV  C+ARN +GE   Q  + +        P FV +     V  G    L
Sbjct: 291 MIRNTRESDQGVYQCMARNSAGEAKTQSAM-LRYSSLPAKPSFVIQPQDTEVLIGTSTTL 349

Query: 511 NARAVGTPTPRITWQKD-GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
              A G P P ITW +D G+ +  +    + T  G   L +      D   + C A N  
Sbjct: 350 ECMATGHPHPLITWTRDNGLEL--DGSRHVATSSG---LYLQNITQRDHGRFTCHANNSH 404

Query: 570 GSTATRARL 578
           G+    A +
Sbjct: 405 GTVQAAANI 413



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 10/183 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           PQF    +D+ V E     + C   G P P + W     Q+  +  H +L   SG   L 
Sbjct: 419 PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVL--SSGT--LR 474

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I      D G   C A +  G      +L V  K   V   F +     +V  G+ + ++
Sbjct: 475 IDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAV---FTQLPQDTSVEVGKNINIS 531

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             A G P P ITW K+GV I  + +  +  +G   TL I  A   D   Y+C A+N  G 
Sbjct: 532 CHAQGEPQPIITWNKEGVQITESGKFHVDDEG---TLTIYDAGFPDQGRYECVARNSFGL 588

Query: 572 TAT 574
             T
Sbjct: 589 AVT 591



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 42/126 (33%), Positives = 55/126 (43%), Gaps = 10/126 (7%)

Query: 3679 LHKRE--EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
            LH R    +T+E+     PR T E +D ++VP G  V+F CR E  G+P   I W HN  
Sbjct: 216  LHGRAVASVTVEEFNCQSPRITFEPQD-VEVPSGNTVYFTCRAE--GNPKPEIIWIHNNH 272

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI----TCSAKRD 3792
                      LN F    L I      D G Y C A N  G A T + +    +  AK  
Sbjct: 273  SLDLEDDTR-LNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPS 331

Query: 3793 IVLESQ 3798
             V++ Q
Sbjct: 332  FVIQPQ 337



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 56/289 (19%), Positives = 112/289 (38%), Gaps = 20/289 (6%)

Query: 69  PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
           P+ P F    ++     G +   E    G+P P+++WTR     ++ +++    +     
Sbjct: 327 PAKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSS----- 381

Query: 129 VSLLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETV 186
             L ++ I   D G +TC A N +G  +A  ++ +Q                   V    
Sbjct: 382 -GLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLC 440

Query: 187 EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG 246
           E  A G        ++   ++         S+   ++D        +    ++++   V 
Sbjct: 441 E--ADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYEC-QAVSSLGVK 497

Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
           +  VQ++ +      P +     Q P+++ ++ G +        G P+P +TW K G ++
Sbjct: 498 KVSVQLTVK------PKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQI 551

Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
             S K  +    +  TL + +    D G Y  +A N  G  VT+ +L V
Sbjct: 552 TESGKFHV---DDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTV 597



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
           V  PPQF V  K    +E   +  E   E  G+P   I W K G  +    + T +   G
Sbjct: 415 VQAPPQFTVTPKDQVVLEEHAV--EWLCEADGNPPPVIVWTKTGGQLPVEGQHT-VLSSG 471

Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            + +D  + +  D G+Y C+AVS+ GV +    L V P+A
Sbjct: 472 TLRIDRAAQH--DQGQYECQAVSSLGVKKVSVQLTVKPKA 509



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 48/175 (27%), Positives = 71/175 (40%), Gaps = 13/175 (7%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V++  G   ++       G+    I W +N  +++     R +  F    L I  T+ +D
Sbjct: 243  VEVPSGNTVYFTCRA--EGNPKPEIIWIHNNHSLDLEDDTR-LNVFDDGTLMIRNTRESD 299

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             G Y C A N  G+A+    +     S   KP F    Q+ E L  G S   EC  +   
Sbjct: 300  QGVYQCMARNSAGEAKTQSAM-LRYSSLPAKPSFVIQPQDTEVL-IGTSTTLEC--MATG 355

Query: 3178 DPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             P   I W   NG  +  S  + T S  G  + +I  TQ  D G + C A N +G
Sbjct: 356  HPHPLITWTRDNGLELDGSRHVATSS--GLYLQNI--TQ-RDHGRFTCHANNSHG 405



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 34/149 (22%), Positives = 73/149 (48%), Gaps = 13/149 (8%)

Query: 219 DDFKVDTFEYRLLREVSFRES-------ITKRYVGESDVQISTEIDRSLGPVSPPKIAQK 271
           DD +++ F+   L   + RES       + +   GE+  Q S  +  S  P  P  + Q 
Sbjct: 278 DDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQ-SAMLRYSSLPAKPSFVIQ- 335

Query: 272 PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
           P+++++  G     +   +G+P P +TW ++    ++ ++H + T+   + L ++N  + 
Sbjct: 336 PQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRH-VATS---SGLYLQNITQR 391

Query: 332 DSGHYTLLAENPNGCIVTSGYLAVESPTE 360
           D G +T  A N +G +  +  + V++P +
Sbjct: 392 DHGRFTCHANNSHGTVQAAANIIVQAPPQ 420



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            +E   Q+P  T   +D+ V      +F  R    G+PK  + W+ N   ++  +  T ++
Sbjct: 227  EEFNCQSPRITFEPQDVEVPSGNTVYFTCRA--EGNPKPEIIWIHNNHSLDLEDD-TRLN 283

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
             F    L ++     D G Y C A N  GEA T S +
Sbjct: 284  VFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAM 320



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            Q P  T   Q+++ +  G T +F CR    G+P  ++ W  N   + D    T+ + F  
Sbjct: 232  QSPRITFEPQDVE-VPSGNTVYFTCRA--EGNPKPEIIWIHNNHSL-DLEDDTRLNVFDD 287

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             ++ I + R+ D+GVY C A N  GE
Sbjct: 288  GTLMIRNTRESDQGVYQCMARNSAGE 313



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 37/118 (31%), Positives = 54/118 (45%), Gaps = 7/118 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+FTV  KD + V E   V + C  +  G+P   I W   G       + HT+   G  
Sbjct: 418  PPQFTVTPKDQV-VLEEHAVEWLCEAD--GNPPPVIVWTKTGGQLPVEGQ-HTVLSSG-- 471

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
             L ID     D G+Y C+A +  G    + ++T   K  + + +QLPQ  S E  K +
Sbjct: 472  TLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKA-LAVFTQLPQDTSVEVGKNI 528



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 5/98 (5%)

Query: 483 IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW--QKDGVPIIPNPELRIH 540
           +E+    +P+       + V  G  V    RA G P P I W      + +  +  L + 
Sbjct: 226 VEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVF 285

Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            DG   TL I   + SD   YQC A+N AG   T++ +
Sbjct: 286 DDG---TLMIRNTRESDQGVYQCMARNSAGEAKTQSAM 320



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 45/185 (24%), Positives = 71/185 (38%), Gaps = 15/185 (8%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP+FT   KD V + E  +   E      G+   VI W   G  +    +  TV + G  
Sbjct: 418  PPQFTVTPKDQVVLEEHAV---EWLCEADGNPPPVIVWTKTGGQLPVEGQ-HTVLSSG-- 471

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L I      D G Y C+A +  G  ++SV+L    K+        T +     ++ G++
Sbjct: 472  TLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALA----VFTQLPQDTSVEVGKN 527

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             +  C      +P   I W   G  +  S +     +    + D  +    D G Y C A
Sbjct: 528  INISCHA--QGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFP---DQGRYECVA 582

Query: 3227 YNKYG 3231
             N +G
Sbjct: 583  RNSFG 587



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 87/391 (22%), Positives = 145/391 (37%), Gaps = 35/391 (8%)

Query: 1967 AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHR 2025
            +V  + F  + P+     ++ EV  G+ V+   T     +P   + W  N   +  +   
Sbjct: 223  SVTVEEFNCQSPRITFEPQDVEVPSGNTVYF--TCRAEGNPKPEIIWIHNNHSLDLEDDT 280

Query: 2026 FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSV----KVDAKSGLYLDTLD 2081
                +D G   L I      D G Y C A N+ GEA T S++     + AK    +   D
Sbjct: 281  RLNVFDDG--TLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQD 338

Query: 2082 EQRL---KKIQELEKYERPKPIEE-------EQPGQRPVFLTALTSLENLKEGDRAHFEC 2131
             + L       E      P P+         E  G R V  ++   L+N+ + D   F C
Sbjct: 339  TEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTC 398

Query: 2132 RVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALD--ILYTYAEDSGTYMCKATNK 2189
                 N+ H T+    N   ++A  ++  T     V  +  + +    D          K
Sbjct: 399  HA---NNSHGTVQAAAN-IIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTK 454

Query: 2190 LGEAV---NTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE-EPKISPPRFV 2245
             G  +      T+  +G   I    QH  G  + + + + G   ++ V+   K       
Sbjct: 455  TGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLG-VKKVSVQLTVKPKALAVF 513

Query: 2246 TELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQ 2305
            T+L   T V  GK  +  C  +   +P   I +   G  +  + +FH+  D G  +L I 
Sbjct: 514  TQLPQDTSVEVGKNINISCHAQ--GEPQPIITWNKEGVQITESGKFHVD-DEG--TLTIY 568

Query: 2306 HCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
                 D G Y   A N+ G   + + +TVTA
Sbjct: 569  DAGFPDQGRYECVARNSFGLAVTNMFLTVTA 599



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 87/398 (21%), Positives = 148/398 (37%), Gaps = 42/398 (10%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL--KAGSR 3468
            +VEE   ++P  T    ++E +  G   +F  R     +P  ++ W  N  SL  +  +R
Sbjct: 225  TVEEFNCQSPRITFEPQDVE-VPSGNTVYFTCRAE--GNPKPEIIWIHNNHSLDLEDDTR 281

Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASM----KVQGKRNIILESQL 3524
               F D     L I  T   D G Y C A N+ GEA T ++M     +  K + +++ Q 
Sbjct: 282  LNVFDDG---TLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQD 338

Query: 3525 PKGMEGTIDKIAAL-EGYSGTVDTLTPE-AESGNPPEFTTTPSDLIL---SENSSAHFEC 3579
             + + GT   +  +  G+   + T T +     +      T S L L   ++     F C
Sbjct: 339  TEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTC 398

Query: 3580 RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHG 3639
                 N+S   V+   N   ++      T+     V+LE        A  + C+A     
Sbjct: 399  H---ANNSHGTVQAAAN--IIVQAPPQFTVTPKDQVVLE------EHAVEWLCEADGNPP 447

Query: 3640 EATVSCK----LQVKGRQGII----LEPQLPSHFKSGTESIQKLEETLHKREEITIEDEK 3691
               V  K    L V+G+  ++    L     +    G    Q +     K+  + +   K
Sbjct: 448  PVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQL-TVK 506

Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG 3751
            P       ++  +  V  G  ++  C  +  G+P   I W   G       + H  ++  
Sbjct: 507  PKALAVFTQLPQDTSVEVGKNINISCHAQ--GEPQPIITWNKEGVQITESGKFHVDDEGT 564

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
                D  +    D G Y C A N +G A T   +T +A
Sbjct: 565  LTIYDAGF---PDQGRYECVARNSFGLAVTNMFLTVTA 599



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 3/102 (2%)

Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629
            V+E   Q+P  T   ++VE+  G   +F  R     +   ++ W HNN  L      T  
Sbjct: 226  VEEFNCQSPRITFEPQDVEVPSGNTVYFTCRA--EGNPKPEIIWIHNNHSLDLEDD-TRL 282

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
            N F    L I +    D G Y C A N+ GEA T    + +S
Sbjct: 283  NVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYS 324



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 38/146 (26%), Positives = 61/146 (41%), Gaps = 8/146 (5%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            V ++T E  +   P  T  P D+ +   ++ +F CR     +    + W HN   L    
Sbjct: 221  VASVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRA--EGNPKPEIIWIHNNHSLDLED 278

Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA-TVSCKLQ---VKGRQGIILEPQ 3660
              + +N F    L I    + D G+Y C A N  GEA T S  L+   +  +   +++PQ
Sbjct: 279  DTR-LNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQ 337

Query: 3661 LPSHFKSGTESIQKLEETLHKREEIT 3686
              +    GT +  +   T H    IT
Sbjct: 338  -DTEVLIGTSTTLECMATGHPHPLIT 362



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 13/152 (8%)

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM--RHSTRI 3198
            V++   Q PR T   Q++E +  G + +F C      +P  +I W HN   +     TR+
Sbjct: 226  VEEFNCQSPRITFEPQDVE-VPSGNTVYFTCRAE--GNPKPEIIWIHNNHSLDLEDDTRL 282

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLA 3258
                D     L I  T+  D G Y C A N  GE  T++ +  Y          +P  + 
Sbjct: 283  NVFDDG---TLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSS-----LPAKPSFVI 334

Query: 3259 KIRELESLQGAQQQTPSTPSAEPPKFITQIQD 3290
            + ++ E L G         +  P   IT  +D
Sbjct: 335  QPQDTEVLIGTSTTLECMATGHPHPLITWTRD 366



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 3/76 (3%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+ ++F C  E +  P  +I W  NN  L      +  + F   +L I +T E D G+Y 
Sbjct: 248  GNTVYFTCRAEGNPKP--EIIWIHNNHSLDLEDDTR-LNVFDDGTLMIRNTRESDQGVYQ 304

Query: 2848 CKATNSKGSATTSGSL 2863
            C A NS G A T  ++
Sbjct: 305  CMARNSAGEAKTQSAM 320



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +PP+    P++  + E    ++  +  GNP P + W K G +L    +H ++++    TL
Sbjct: 417 APPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSS---GTL 473

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
           R+    + D G Y   A +  G    S  L V+
Sbjct: 474 RIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVK 506



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q+P+ +    ++E   G  V+  CR +  G+    + W  N   +      R    FD  
Sbjct: 232  QSPRITFEPQDVEVPSGNTVYFTCRAE--GNPKPEIIWIHNNHSLDLEDDTR-LNVFDDG 288

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
             L + +    D GVY C A N  GEA T  A+
Sbjct: 289  TLMIRNTRESDQGVYQCMARNSAGEAKTQSAM 320



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 21/69 (30%), Positives = 29/69 (42%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T   ++  S     P FV  P    V  G      C  TGHP P + W  +    ++GSR
Sbjct: 316  TQSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSR 375

Query: 4157 YKLTYDGMY 4165
            +  T  G+Y
Sbjct: 376  HVATSSGLY 384



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV  PP+F    K   V E   V + C  +    P   I W + G  LP   ++ TV   
Sbjct: 414  IVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPV--IVWTKTGGQLPVEGQH-TVLSS 470

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911
            G + +D       D G+Y C+AV+  G
Sbjct: 471  GTLRID--RAAQHDQGQYECQAVSSLG 495



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT--IVNGSRYKL 4159
            VEE   + P +    P  V V  G    F CR  G+PKP ++W+ N ++  + + +R  +
Sbjct: 226  VEEFNCQSPRITFE-PQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNV 284

Query: 4160 TYDGMYHFDIPKTRQYDTG 4178
              DG     I  TR+ D G
Sbjct: 285  FDDGT--LMIRNTRESDQG 301



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 10/138 (7%)

Query: 1802 VQSKASLQLE--SQHESALQKIQQLEDSSRYQRREDVEVAVN-QAPRFITQLNGPTKLSE 1858
            V S  +L+++  +QH+    + Q +  SS   ++  V++ V  +A    TQL   T +  
Sbjct: 467  VLSSGTLRIDRAAQHDQGQYECQAV--SSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEV 524

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G++ +  C  +  P P   + W   G  +    ++   ++     L I      D G Y 
Sbjct: 525  GKNINISCHAQGEPQPI--ITWNKEGVQITESGKFHVDDE---GTLTIYDAGFPDQGRYE 579

Query: 1919 CKAINNLGQAVSSIRLNV 1936
            C A N+ G AV+++ L V
Sbjct: 580  CVARNSFGLAVTNMFLTV 597



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 35/125 (28%), Positives = 46/125 (36%), Gaps = 4/125 (3%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            V+  VKP    +FT+  Q   V   +         GEP P+I W +E   I  S  F + 
Sbjct: 501  VQLTVKPKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVD 560

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE-KRRQGRGGIVPPSFTLT 4519
               T   L I      D   +  VA N  G A  +  L V   + RQ     V  S    
Sbjct: 561  DEGT---LTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQAGDDFVESSILDA 617

Query: 4520 AQNVN 4524
             Q V+
Sbjct: 618  VQRVD 622



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 7/78 (8%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNG--VTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714
            G  VY   + E    P  +I W  N   + L    RL + FD G  TL I + R  D G+
Sbjct: 248  GNTVYFTCRAEGNPKP--EIIWIHNNHSLDLEDDTRL-NVFDDG--TLMIRNTRESDQGV 302

Query: 2715 YTCKATNLLGEAVSTASI 2732
            Y C A N  GEA + +++
Sbjct: 303  YQCMARNSAGEAKTQSAM 320



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 32/138 (23%), Positives = 55/138 (39%), Gaps = 5/138 (3%)

Query: 1669 VHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAA 1728
            V +   +YL++  +    R     + S     +A + ++   P FT+  KD  V E  A 
Sbjct: 377  VATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAV 436

Query: 1729 HFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAI 1788
             +       G+P   + W + G  +    + T +       L +      D G Y C+A+
Sbjct: 437  EWLCEAD--GNPPPVIVWTKTGGQLPVEGQHTVLSSG---TLRIDRAAQHDQGQYECQAV 491

Query: 1789 NELGEAVTSSTLFVQSKA 1806
            + LG    S  L V+ KA
Sbjct: 492  SSLGVKKVSVQLTVKPKA 509



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 6/96 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+F    KDQ+ ++E      E   E  G+    + W K G  +    + T   +     
Sbjct: 419  PQFTVTPKDQVVLEEHAV---EWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSG---T 472

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            L I     HD G Y C+A +++G    S  LT+  K
Sbjct: 473  LRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPK 508



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 6/82 (7%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADT 1247
            V  G  ++  CR E  G+P   + W HN  S+ +    +   +D G   L I +   +D 
Sbjct: 245  VPSGNTVYFTCRAE--GNPKPEIIWIHNNHSLDLEDDTRLNVFDDG--TLMIRNTRESDQ 300

Query: 1248 GEYTVRAVNHLGSAHT-SAIVR 1268
            G Y   A N  G A T SA++R
Sbjct: 301  GVYQCMARNSAGEAKTQSAMLR 322



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 3/74 (4%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-- 4163
            K +   VF  LP   +VE G+     C   G P+P + W   G  I    ++ +  +G  
Sbjct: 506  KPKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTL 565

Query: 4164 -MYHFDIPKTRQYD 4176
             +Y    P   +Y+
Sbjct: 566  TIYDAGFPDQGRYE 579



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+     + V    G  ++F  R E  G+P  +I W+ N  S++     T +  F   +L
Sbjct: 234 PRITFEPQDVEVPSGNTVYFTCRAE--GNPKPEIIWIHNNHSLDLEDD-TRLNVFDDGTL 290

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVL 726
            + +    D G Y C A ++ G A+T++ +
Sbjct: 291 MIRNTRESDQGVYQCMARNSAGEAKTQSAM 320



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 3/70 (4%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G    F  +  GNP P + W      L   +   +   +   D +L+I+     D+G Y 
Sbjct: 248 GNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFD---DGTLMIRNTRESDQGVYQ 304

Query: 146 CTARNQYGEA 155
           C ARN  GEA
Sbjct: 305 CMARNSAGEA 314



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 4/87 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            Q+PR IT      ++  G + ++ CR E  P P   + W  N   L      R  N F  
Sbjct: 232  QSPR-ITFEPQDVEVPSGNTVYFTCRAEGNPKPE--IIWIHNNHSLDLEDDTRL-NVFDD 287

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQA 1928
              L I      D G Y C A N+ G+A
Sbjct: 288  GTLMIRNTRESDQGVYQCMARNSAGEA 314



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/111 (21%), Positives = 46/111 (41%), Gaps = 8/111 (7%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR-NGVPIEASNRLTTMHDFGYVA 1769
            P F +  +D  V    +   E   +  G P   + W R NG+ ++ S  + T        
Sbjct: 330  PSFVIQPQDTEVLIGTSTTLEC--MATGHPHPLITWTRDNGLELDGSRHVATSS-----G 382

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQK 1820
            L ++ +   D G +TC A N  G    ++ + VQ+     +  + +  L++
Sbjct: 383  LYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEE 433



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 7/82 (8%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN--RIQTYHDFGYVALDIASVRAE 1111
            ++  G + +F  R E   +    + W  N   +   +  R+  + D     L I + R  
Sbjct: 244  EVPSGNTVYFTCRAE--GNPKPEIIWIHNNHSLDLEDDTRLNVFDDG---TLMIRNTRES 298

Query: 1112 DSGVYTVVARNAAGEAQLSASM 1133
            D GVY  +ARN+AGEA+  ++M
Sbjct: 299  DQGVYQCMARNSAGEAKTQSAM 320



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 2/74 (2%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF 4167
            + PP F   P    V E     + C   G+P P ++W   G  +    ++ +   G    
Sbjct: 416  QAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRI 475

Query: 4168 DIPKTRQYDTGKIE 4181
            D  +  Q+D G+ E
Sbjct: 476  D--RAAQHDQGQYE 487



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/125 (24%), Positives = 49/125 (39%), Gaps = 5/125 (4%)

Query: 1280 QNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGD 1339
            Q++Q   + Q +     +   V+  +       F++   +     G N+++ C  Q  G+
Sbjct: 480  QHDQGQYECQAVSSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINISCHAQ--GE 537

Query: 1340 QTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCA 1399
                + W   G  I    +F    E      D  + +P D G Y C A N  G AVT+  
Sbjct: 538  PQPIITWNKEGVQITESGKFHVDDEGTLTIYD--AGFP-DQGRYECVARNSFGLAVTNMF 594

Query: 1400 LRVIA 1404
            L V A
Sbjct: 595  LTVTA 599


>AK092284-1|BAC03850.1|  885|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34965 fis, clone NTONG2004308. ).
          Length = 885

 Score =  106 bits (255), Expect = 2e-21
 Identities = 111/421 (26%), Positives = 164/421 (38%), Gaps = 28/421 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129
           PP F +     +  +     F  ++ G P P V W R K+ L    +  M   E+ G+V 
Sbjct: 463 PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKM---ERVGNVC 519

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEA--ICSVYIQPEGXXXXXXXXXXXXXYRHVSE--- 184
           SL I  I  G+ GEY C A N  GEA    +V I P+              ++HV E   
Sbjct: 520 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQ--EERVVALPPPVTHQHVMEFDL 577

Query: 185 --TVEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
             T   +    Q    E     + V  +       +  DF  D     +  +V     + 
Sbjct: 578 EHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPDFTPDHKSMIVSLDVLPFNFVD 637

Query: 242 KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
                        +ID  +  + PP+      + K+ E +DA F+  + G P P V W+K
Sbjct: 638 PNMDSREGEDKELKIDLEVFEM-PPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYK 696

Query: 302 NGQRLINSN-KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
               +   N K+ I       TL++RN   SDS  Y   A N  G  +  G+L +     
Sbjct: 697 EYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEI 756

Query: 361 SYVQDQRSQYITDTQQRE-------TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
             V  ++S+    +   E       T+   E       P+F+K   D     G    F C
Sbjct: 757 FAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC 816

Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN--HALMITNVTLSDSGVVTCVARNKS 471
            V G P P V W+ + + ++     +  V ESG   H L IT++  SD G   CVA NKS
Sbjct: 817 LVRGSPRPTVYWYKDGKLVQ---GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKS 873

Query: 472 G 472
           G
Sbjct: 874 G 874



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 71/236 (30%), Positives = 110/236 (46%), Gaps = 10/236 (4%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMH 1763
            EV    P F MP+ D ++ EN  A F+  +I +  P+  V+W +  + IE  N +     
Sbjct: 655  EVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISE 712

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-QSKASLQLESQHESALQKI- 1821
            + G   L ++ V   DS TY CRA+N +GEA+    L +  S+    +  + +  L  + 
Sbjct: 713  EKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLM 772

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            ++L   S Y         V   PRFI  ++       G +A+++C +   P P   V WY
Sbjct: 773  EELVLKSNYTDSFFEFQVVEGPPRFIKGISD-CYAPIGTAAYFQCLVRGSPRPT--VYWY 829

Query: 1882 FNGKVLQSGHRYRTSND-FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +GK++Q G R+       GF  L I ++   D GEY C A N  G A S   L +
Sbjct: 830  KDGKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 884



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 104/467 (22%), Positives = 175/467 (37%), Gaps = 46/467 (9%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP   +     K+ E     F V++ G P P V W++N   L    + ++    N  +L 
Sbjct: 463 PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLE 522

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           + N QK + G Y   A N  G   +   + +  P E  V          T Q   E  +E
Sbjct: 523 ISNIQKGEGGEYMCHAVNIIGEAKSFANVDI-MPQEERVVALPPPV---THQHVMEFDLE 578

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            +  +  P   ++  + +++E  +  F+ +V     P+ T                    
Sbjct: 579 HTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPDFT-------------------- 618

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETA-FQCRLNVIEKEQVVAPKFVERFSTLNVR 503
             +H  MI ++ +     V     ++ GE    +  L V E    + P+F+       + 
Sbjct: 619 -PDHKSMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFE----MPPRFIMPICDFKIP 673

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQ 562
           E    V     +G PTP + W K+ + I P N +  I  + G+ TL I     SD+A Y+
Sbjct: 674 ENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYR 733

Query: 563 CTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERAR 622
           C A N  G    R  L            K+  +   + +            +        
Sbjct: 734 CRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFF------- 786

Query: 623 PYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEAS 682
                 E   V  PP+FI  +    A  G   +F+  +   G P   + W K+G+ ++  
Sbjct: 787 ------EFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVR--GSPRPTVYWYKDGKLVQGR 838

Query: 683 SRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
                    G+ +L + SL   D GEY C A + +G+AE+ A L +T
Sbjct: 839 RFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 885



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 65/228 (28%), Positives = 95/228 (41%), Gaps = 27/228 (11%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD-IRNKILEEDGTYT 4570
            +PP F +   +  +           V G    +V W K    ++PD I+  I EE G++T
Sbjct: 659  MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHT 718

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARC-------DAECVVSLPATKDKPKPQT------- 4616
            L I      DS  Y C A+N  GEA C       D+E + ++ A K K    +       
Sbjct: 719  LKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSE-IFAVIAKKSKVTLSSLMEELVL 777

Query: 4617 -----------KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                       +    PP  I+ + D     G A  F C + G P PTV WYK  KL++ 
Sbjct: 778  KSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQG 837

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             ++         + L I+     DEG+Y+CVA N +G     A L +T
Sbjct: 838  RRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 885



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 101/454 (22%), Positives = 172/454 (37%), Gaps = 58/454 (12%)

Query: 4396 TQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP 4455
            T    +E P     PP F + +   +V+E+    F VE +G P+P +KWYR    ++  P
Sbjct: 450  TPNEAIE-PKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLE--P 506

Query: 4456 DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
            D +I      ++          S   + + +  GG   C A  ++ E +      I+P  
Sbjct: 507  DERIKMERVGNVC---------SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQE 557

Query: 4516 FTLTAQNVNVTSGQLVRLDTKVTGTK--PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
              + A    VT   ++  D + T +   P     +   +  + D++    E +    ++ 
Sbjct: 558  ERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLEVELSEKDVK----EFEKQVKIVT 613

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
            +  +  D  K   V+++       D   + S      + K   +    PP  I P+ D  
Sbjct: 614  VPDFTPDH-KSMIVSLDVLPFNFVDPN-MDSREGEDKELKIDLEVFEMPPRFIMPICDFK 671

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY-FQMSRTADEYTLRISEAFPEDEGD 4692
            + E     F C ++G P P V+WYK    I+P    + +S     +TL+I      D   
Sbjct: 672  IPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSAT 731

Query: 4693 YKCVAYNSAGR---------------VTVAAKLKVTQPDQADNLPALTPLRD----IVVY 4733
            Y+C A N  G                  +A K KVT     + L   +   D      V 
Sbjct: 732  YRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVV 791

Query: 4734 EGQP----------------AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN-A 4776
            EG P                A F+  +    +PT+ W ++G L+ +   F +   G    
Sbjct: 792  EGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRRFTVEESGTGFH 850

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L I +  + D G + C AT  +G  E+ A L +
Sbjct: 851  NLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 884



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 65/233 (27%), Positives = 102/233 (43%), Gaps = 13/233 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GF 3752
            PPRF + I D   +PE     F C V  +G PT  + W+         +  + +++  G 
Sbjct: 660  PPRFIMPICD-FKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGS 716

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
              L I  +   D+  Y CRA N  G A     +T        + ++  +      ++EL 
Sbjct: 717  HTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELV 776

Query: 3813 -RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
             +   +D+  E  +V  PP+FI  I            F+C V  +  P+  + WY++GKL
Sbjct: 777  LKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLV--RGSPRPTVYWYKDGKL 834

Query: 3872 LPSGHRYRTVYD--MGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKATIS 3920
            +  G R+ TV +   GF +L I  +   D GEY C A N  G  E F   T++
Sbjct: 835  V-QGRRF-TVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 885



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 60/228 (26%), Positives = 99/228 (43%), Gaps = 8/228 (3%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS-RFTSIFRFGYI 694
           PP+FI+P+      E     F+  +  +G PT +++W K    IE  + ++      G  
Sbjct: 660 PPRFIMPICDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 717

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE-TLQYI-QQLED 752
           +L + ++ + DS  Y CRAV+  G A  +  L +         ++  + TL  + ++L  
Sbjct: 718 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 777

Query: 753 YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
            S Y       +     P+FI+ + D      G  A+F+  +     PT  V WYKDG+ 
Sbjct: 778 KSNYTDSFFEFQVVEGPPRFIKGISDC-YAPIGTAAYFQCLVRGSPRPT--VYWYKDGKL 834

Query: 813 ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
           +            G+ +L I  L   D G Y   A NK G A S A++
Sbjct: 835 VQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 882



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 64/244 (26%), Positives = 105/244 (43%), Gaps = 16/244 (6%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSGHRYRTVYD 3883
            +   PP+FI  I    + E+    F+C V     P+  ++WY+    + P   +Y    +
Sbjct: 656  VFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISEE 713

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEAL 3943
             G  +L I  V   DS  Y CRAVN  GE   +  ++   + D  +   + +  K + + 
Sbjct: 714  KGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLT---MGDSEIFAVIAKKSKVTLSS 770

Query: 3944 TQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDP 4003
               E  +K   ++ +      + V  + PPRF+  I    + +      F+C +   G P
Sbjct: 771  LMEELVLKSNYTDSFFE----FQV-VEGPPRFIKGISDCYAPIG-TAAYFQCLVR--GSP 822

Query: 4004 NMKVEWFFNGKPLLHKNRFT-PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAV 4062
               V W+ +GK L+   RFT      G+  +    +   D GEY C ATN  GM E+ A 
Sbjct: 823  RPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAA 881

Query: 4063 IKTT 4066
            +  T
Sbjct: 882  LTLT 885



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 63/230 (27%), Positives = 100/230 (43%), Gaps = 9/230 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYV 967
            P F  PI D   I E   A F+  +  IG  T  V+W K+   +E  + +       G  
Sbjct: 661  PRFIMPICD-FKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 717

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK--DIIAESQHPGGLEKIQYLED 1025
             L I++V + D+  Y CRA N +G+A     LT+   +   +IA+         ++ L  
Sbjct: 718  TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 777

Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQ 1085
             S Y+    E   +   PRF+  +      + G +A+F+  V  +     TV WY +GK 
Sbjct: 778  KSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLV--RGSPRPTVYWYKDGKL 834

Query: 1086 ITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +            G+  L I S+   D G Y  VA N +G A+  A++T+
Sbjct: 835  VQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 884



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 67/235 (28%), Positives = 97/235 (41%), Gaps = 16/235 (6%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI--NDFGF 3614
            PP F     D  + ENS A F+C +I +   +  V+W+      +    +K +   + G 
Sbjct: 660  PPRFIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKE-YMCIEPDNIKYVISEEKGS 716

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ--GIILEPQLPSHFKSGTESI 3672
              L+I  V   D+  Y C+A N  GEA     L +   +   +I +    +      E +
Sbjct: 717  HTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELV 776

Query: 3673 QKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWF 3732
             K   T    E   +E     PPRF   I D    P G   +F C V   G P   + W+
Sbjct: 777  LKSNYTDSFFEFQVVE----GPPRFIKGISD-CYAPIGTAAYFQCLVR--GSPRPTVYWY 829

Query: 3733 HNGRPFATGSRVHT-LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             +G+    G R     +  GF  L I  +   D GEY C ATNK G A + A +T
Sbjct: 830  KDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALT 883



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 89/331 (26%), Positives = 136/331 (41%), Gaps = 32/331 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI---EASHRIRTVYAF-----GMVV-LEI 3110
            + E  + H  +S  P+  Q +V+E   + K +   E   +I TV  F      M+V L++
Sbjct: 572  VMEFDLEHTTSSRTPS-PQEIVLEVELSEKDVKEFEKQVKIVTVPDFTPDHKSMIVSLDV 630

Query: 3111 LGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            L     D    S    +K    E+ + LE  +      PRF   I + + + +   A F+
Sbjct: 631  LPFNFVDPNMDSREGEDK----ELKIDLEVFE----MPPRFIMPICDFK-IPENSDAVFK 681

Query: 3171 CTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNK 3229
            C+V+ +  P++K  WY     +        +S+  G   L I      DS  Y CRA N 
Sbjct: 682  CSVIGIPTPEVK--WYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNC 739

Query: 3230 YGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE----PPKFI 3285
             GE   R  +   G   ++    +   +     +E L      T S    +    PP+FI
Sbjct: 740  VGEAICRGFLTM-GDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFI 798

Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD-FGIVILDI 3344
              I D    + G +A+F+  LV    P   V W+ +GK L  G R+       G   L I
Sbjct: 799  KGISDCYAPI-GTAAYFQC-LVR-GSPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFI 854

Query: 3345 LYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
                + + GEY CVATNK G   + A L  T
Sbjct: 855  TSLVKSDEGEYRCVATNKSGMAESFAALTLT 885



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 63/235 (26%), Positives = 99/235 (42%), Gaps = 15/235 (6%)

Query: 2363 KRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-D 2421
            K  +I   V    P F  P+ +   I E   A F C +I  G PT +V+W++    IE D
Sbjct: 648  KELKIDLEVFEMPPRFIMPICDF-KIPENSDAVFKCSVI--GIPTPEVKWYKEYMCIEPD 704

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHP 2481
            + +   + + G  ++ I +V   D   Y CRA N +GE                +  +  
Sbjct: 705  NIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAK-- 762

Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIF---TQVLTGPSELWE--GQHAHYEARVVPVG 2536
            +    +  L +    +S   D  FE  +     + + G S+ +   G  A+++  V   G
Sbjct: 763  KSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLV--RG 820

Query: 2537 DPSLRFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
             P     WY +G +L  G RF       GF  L I S+V +D G Y C A N++G
Sbjct: 821  SPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 874



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 56/232 (24%), Positives = 99/232 (42%), Gaps = 7/232 (3%)

Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGS-RFTETN 1630
            EV    P     + + +I E   A F+  +I +   T +V+WY     ++  + ++  + 
Sbjct: 655  EVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIP--TPEVKWYKEYMCIEPDNIKYVISE 712

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG-IAIVHSKKSIYLESQHEGALPRL- 1688
              G   L I +    DS TY CRA+N +GEA+  G + +  S+    +  + +  L  L 
Sbjct: 713  EKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLM 772

Query: 1689 NQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748
             +L   S Y     + +V+   P F   + D       AA+F+   +  G P+  V W +
Sbjct: 773  EELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC--LVRGSPRPTVYWYK 830

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
            +G  ++           G+  L +  +   D G Y C A N+ G A + + L
Sbjct: 831  DGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 882



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 60/233 (25%), Positives = 101/233 (43%), Gaps = 22/233 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH-RFKTTYDFGYVA 2036
            P+F  PI + ++ E      + ++  +  PT  V+WY     ++  + ++  + + G   
Sbjct: 661  PRFIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYMCIEPDNIKYVISEEKGSHT 718

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAV-----TTSSVKVDA----KSGLYLDTLDEQRLKK 2087
            L I      D+ TY C+A N VGEA+     T    ++ A    KS + L +L E+ + K
Sbjct: 719  LKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLK 778

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                + +   + +E       P F+  ++       G  A+F+C V     P  T+ W+ 
Sbjct: 779  SNYTDSFFEFQVVEGP-----PRFIKGISDC-YAPIGTAAYFQCLVR--GSPRPTVYWYK 830

Query: 2148 NGQKIRAGHRYRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
            +G K+  G R+       G+  L I      D G Y C ATNK G A +   L
Sbjct: 831  DG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 882



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 60/232 (25%), Positives = 96/232 (41%), Gaps = 12/232 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH-RYRTTHDFGYV 2167
            P F+  +   + + E   A F+C V  I  P   + W+     I   + +Y  + + G  
Sbjct: 661  PRFIMPICDFK-IPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISEEKGSH 717

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR--NIILDTQHPNGLEKIRQLEA 2225
             L I      DS TY C+A N +GEA+    L +       +I           + +L  
Sbjct: 718  TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 777

Query: 2226 QGHSTRIEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKA 2284
            + + T    E   +  PPRF+  +    +   G  A+F+C V     P   + +Y +GK 
Sbjct: 778  KSNYTDSFFEFQVVEGPPRFIKGI-SDCYAPIGTAAYFQCLVR--GSPRPTVYWYKDGKL 834

Query: 2285 LQSAARFHI-TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
            +Q   RF +     G+ +L I   V  D GEY   A N  G   S  ++T+T
Sbjct: 835  VQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 885



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 51/238 (21%), Positives = 105/238 (44%), Gaps = 10/238 (4%)

Query: 2224 EAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGK 2283
            E +    +I++E  ++ PPRF+  +     + E   A F+C V  +  P   +++Y    
Sbjct: 644  EGEDKELKIDLEVFEM-PPRFIMPICDFK-IPENSDAVFKCSVIGIPTPE--VKWYKEYM 699

Query: 2284 ALQ-SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAISMTVTAKGSI 2340
             ++    ++ I+ + G  +L I++    D+  Y  +A+N +G   C   ++M  +   ++
Sbjct: 700  CIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAV 759

Query: 2341 ISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRL 2400
            I++  +      + EL     +        V    P F + + +      G  A+F C  
Sbjct: 760  IAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDC-YAPIGTAAYFQC-- 816

Query: 2401 IPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            +  G P   V W+++ KL++      +    G+ ++ I+ +   DEG Y C A+N  G
Sbjct: 817  LVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 874



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 62/232 (26%), Positives = 102/232 (43%), Gaps = 16/232 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYVSLD 2834
            FI  + +    E  +  F+C+V     PT +++W+     + P   +Y  + +    +L 
Sbjct: 663  FIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 720

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I +    DS  Y C+A N  G A   G L   GD  I F     + K  L ++   EE  
Sbjct: 721  IRNVCLSDSATYRCRAVNCVGEAICRGFLTM-GDSEI-FAVIAKKSKVTLSSL--MEELV 776

Query: 2895 LAKGRRPSVPDTEYPK--PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            L      S  + +  +  P +I  I+  +  + G   + +  V  +  P   + WY +GK
Sbjct: 777  LKSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLV--RGSPRPTVYWYKDGK 833

Query: 2953 VLEQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRG--EAFTSSTV 3001
            ++ QG RF +  S  GF  L +  + + D G Y C A NK G  E+F + T+
Sbjct: 834  LV-QGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 884



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 61/237 (25%), Positives = 96/237 (40%), Gaps = 14/237 (5%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
            K+  I  E   + PRF+  P     + E     F+C +  +    +K  W+K    +   
Sbjct: 648  KELKIDLEVFEMPPRFIM-PICDFKIPENSDAVFKCSVIGIPTPEVK--WYKEYMCIEPD 704

Query: 1491 H-RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR-LTCRSTTDIVRSTQN 1548
            + ++    + G   L I ++   DS  Y CRAVN VG  E  CR       ++I      
Sbjct: 705  NIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVG--EAICRGFLTMGDSEIFAVIAK 762

Query: 1549 EAGLEQIQVLED---RSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVS 1605
            ++ +    ++E+   +S Y  +    +V    P     + +     G  A+F+   +   
Sbjct: 763  KSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQ--CLVRG 820

Query: 1606 DATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
                 V WY + K L  G RFT E +  GF  L I S +  D G Y C A N  G A
Sbjct: 821  SPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 876



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 12/225 (5%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFRTFCDFGFV 3478
            P F +P+ + + + E  +A F+  +     P +K  WY     ++  + ++    + G  
Sbjct: 661  PRFIMPICDFK-IPENSDAVFKCSVIGIPTPEVK--WYKEYMCIEPDNIKYVISEEKGSH 717

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
             L+I      DS  Y CRA N  GEA+    + +       + ++  K    ++ +   L
Sbjct: 718  TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 777

Query: 3539 EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGK 3598
            +  S   D+         PP F    SD      ++A+F+C  +        V W+ +GK
Sbjct: 778  K--SNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC--LVRGSPRPTVYWYKDGK 833

Query: 3599 PLLTGSRVKTINDFG--FVILEIGGVYQRDAGLYTCKATNRHGEA 3641
             L+ G R  T+ + G  F  L I  + + D G Y C ATN+ G A
Sbjct: 834  -LVQGRRF-TVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 876



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 59/243 (24%), Positives = 102/243 (41%), Gaps = 13/243 (5%)

Query: 1299 KQVREDITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            K+++ D+ V + P +F   + + +  E ++   +C +  +G  T  V+W+     I+  +
Sbjct: 648  KELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDN 705

Query: 1358 -RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
             ++  + E     L + +V   DS  Y C+A N +GEA+    L  +   ++       S
Sbjct: 706  IKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL-TMGDSEIFAVIAKKS 764

Query: 1417 GLEKIQYLED---TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTD 1473
             +     +E+    S Y  +    + V   PRF+         I G   +F+C +     
Sbjct: 765  KVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLVR--GS 821

Query: 1474 SNLKVEWFKNGQPVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
                V W+K+G+ V  G RF       G+  L I  L+  D G Y C A N  G  E   
Sbjct: 822  PRPTVYWYKDGKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFA 880

Query: 1533 RLT 1535
             LT
Sbjct: 881  ALT 883



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 48/201 (23%), Positives = 80/201 (39%), Gaps = 9/201 (4%)

Query: 2672 PNLKIEWFKNGVTLTT-GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P  +++W+K  + +     +   + + G  TL I ++   DS  Y C+A N +GEA+   
Sbjct: 688  PTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRG 747

Query: 2731 SIKIEDRHWLL----GESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCK 2786
             + + D            +   SL     L                   FI  +++    
Sbjct: 748  FLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAP 807

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSLDITHTYEEDSGI 2845
             G   +F+C V  S  PT  + W+ + K L  G R+      + + +L IT   + D G 
Sbjct: 808  IGTAAYFQCLVRGSPRPT--VYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGE 864

Query: 2846 YTCKATNSKGSATTSGSLRCT 2866
            Y C ATN  G A +  +L  T
Sbjct: 865  YRCVATNKSGMAESFAALTLT 885



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 5/107 (4%)

Query: 2355 ELESAEPFKRP-EIPEPVTRQRPV-FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEW 2412
            E+  ++ F  P E  EP   + P  F +PL     + E  T  F   +   G P   V+W
Sbjct: 441  EIWRSDSFGTPNEAIEPKDNEMPPSFIEPLTK-RKVYENTTLGFIVEV--EGLPVPGVKW 497

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +RN+ L+E   RI         S+ IS+++  + G YMC A N++GE
Sbjct: 498  YRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGE 544



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 14/166 (8%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI- 694
           PP FI PL      E   + F   +E  G P   ++W +N   +E   R   + R G + 
Sbjct: 463 PPSFIEPLTKRKVYENTTLGFIVEVE--GLPVPGVKWYRNKSLLEPDERI-KMERVGNVC 519

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
           SL++ ++   + GEY C AV+  G A++ A + + P+         P T Q++ + +   
Sbjct: 520 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFD--- 576

Query: 755 KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDP 800
                  +E  TS R    + +    EL E     FE Q+  V+ P
Sbjct: 577 -------LEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVP 615



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI  +    V E+  + F   VE    P   ++WYRN  LL    R +        S
Sbjct: 463  PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDERIKMERVGNVCS 520

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L+I  +   + GEY+C AVN  GE
Sbjct: 521  LEISNIQKGEGGEYMCHAVNIIGE 544



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 49/204 (24%), Positives = 80/204 (39%), Gaps = 8/204 (3%)

Query: 2535 VGDPSLRFEWYINGVELKMGS-RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXX 2593
            +G P+   +WY   + ++  + ++  + + G  TL I +V  +D+  Y C+A+N  G   
Sbjct: 685  IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAI 744

Query: 2594 XXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAM--NKVPEMFVDTGVQQAPIFTTHLKSY 2651
                            A + +      ++E  +  N     F    V+  P F   +   
Sbjct: 745  CRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDC 804

Query: 2652 DKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRND 2710
               + G   Y +  V  R  P   + W+K+G  L  G R        G   L I SL   
Sbjct: 805  YAPI-GTAAYFQCLV--RGSPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKS 860

Query: 2711 DSGIYTCKATNLLGEAVSTASIKI 2734
            D G Y C ATN  G A S A++ +
Sbjct: 861  DEGEYRCVATNKSGMAESFAALTL 884



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 4/112 (3%)

Query: 381 ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
           E IE  +  + P F++    R V E     F   V G P P V W+ N   +  D   +I
Sbjct: 453 EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPD--ERI 510

Query: 441 LVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI-EKEQVVA 490
            +   GN  +L I+N+   + G   C A N  GE      ++++ ++E+VVA
Sbjct: 511 KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVA 562



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 2/107 (1%)

Query: 1834 EDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
            E +E   N+ P    +     K+ E  +  +   +E  P P   V+WY N  +L+   R 
Sbjct: 453  EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDERI 510

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            +        +L+I  +   + GEY C A+N +G+A S   +++  +E
Sbjct: 511  KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQE 557



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 47/195 (24%), Positives = 74/195 (37%), Gaps = 7/195 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKN-RFTPIYDF 4028
            + PPRF+  I     + E     F+C +  +G P  +V+W+     +   N ++    + 
Sbjct: 658  EMPPRFIMPI-CDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEK 714

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIR 4088
            G   +    V   DS  Y CRA N  G    +  + T G   I +     K   ++  + 
Sbjct: 715  GSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL-TMGDSEI-FAVIAKKSKVTLSSLM 772

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            E         +   E      PP F+          G  A F C V G P+P V W  +G
Sbjct: 773  EELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDG 832

Query: 4149 NTIVNGSRYKLTYDG 4163
              +V G R+ +   G
Sbjct: 833  K-LVQGRRFTVEESG 846



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 48/197 (24%), Positives = 78/197 (39%), Gaps = 11/197 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGS-RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P  +++WY     +E  + ++ ++ + G  TL + +V   DS  Y C+A N  GEA    
Sbjct: 688  PTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRG 747

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDD---TGRPPEFTTVFKD 3056
              + T  D+ I      K    L  +  +E+ + K        +      PP F     D
Sbjct: 748  --FLTMGDSEIFAVIAKKSKVTLSSL--MEELVLKSNYTDSFFEFQVVEGPPRFIKGISD 803

Query: 3057 IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTT 3116
                  G  A+++   +  G     + W+ +GK ++           G   L I     +
Sbjct: 804  CY-APIGTAAYFQC--LVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKS 860

Query: 3117 DSGTYSCRATNKWGQAE 3133
            D G Y C ATNK G AE
Sbjct: 861  DEGEYRCVATNKSGMAE 877



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 62/230 (26%), Positives = 94/230 (40%), Gaps = 17/230 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN-RIQTYHDFGYV 1101
            PRF+ P+    KI E   A F+  V      T  V+WY     I   N +     + G  
Sbjct: 661  PRFIMPICDF-KIPENSDAVFKCSVIGIP--TPEVKWYKEYMCIEPDNIKYVISEEKGSH 717

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEE-- 1159
             L I +V   DS  Y   A N  GEA     +T+   S I      +     +  +EE  
Sbjct: 718  TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGD-SEIFAVIAKKSKVTLSSLMEELV 776

Query: 1160 --SKFVEPMYQIEEISKSKPVFVQPLSNP-PPVSEGKNIHLECRLEPMGDPTMRVEWFHN 1216
              S + +  ++ + + +  P F++ +S+   P+  G   + +C +   G P   V W+ +
Sbjct: 777  LKSNYTDSFFEFQVV-EGPPRFIKGISDCYAPI--GTAAYFQCLVR--GSPRPTVYWYKD 831

Query: 1217 GRSVTVGSRFKTYYD-FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
            G+ V  G RF       GF  L I     +D GEY   A N  G A + A
Sbjct: 832  GKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFA 880



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F +   +     G  A F+  +RG+P P V W  K   LV+  ++++     TG  +
Sbjct: 794 PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWY-KDGKLVQGRRFTVE-ESGTGFHN 851

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEA 155
           L I  +   DEGEY C A N+ G A
Sbjct: 852 LFITSLVKSDEGEYRCVATNKSGMA 876



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 20/94 (21%), Positives = 40/94 (42%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
           K+  + P F+E  +   V E   +       G P P + W ++   + P+  +++   G 
Sbjct: 458 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 517

Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +L+I   +  +   Y C A N+ G   + A +
Sbjct: 518 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 551



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 2/82 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+ E   +    +VE    P +K  W++N   L    R+K      + +L I++++  + 
Sbjct: 474  KVYENTTLGFIVEVEGLPVPGVK--WYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEG 531

Query: 2713 GIYTCKATNLLGEAVSTASIKI 2734
            G Y C A N++GEA S A++ I
Sbjct: 532  GEYMCHAVNIIGEAKSFANVDI 553



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 4/97 (4%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            D E P P +I P+  + ++ E   L    +VE    P +K  WY N  +LE   R K+  
Sbjct: 459  DNEMP-PSFIEPLT-KRKVYENTTLGFIVEVEGLPVPGVK--WYRNKSLLEPDERIKMER 514

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
                 +L++ ++ + + G Y C A N  GEA + + V
Sbjct: 515  VGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 551



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 760 ESIEEQTSQRP-QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
           E+IE + ++ P  FI PL    ++ E     F  ++  +  P   V+WY++   +    R
Sbjct: 453 EAIEPKDNEMPPSFIEPLTKR-KVYENTTLGFIVEVEGL--PVPGVKWYRNKSLLEPDER 509

Query: 819 ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQR 878
           I         SL I +++  + G Y   AVN +GEA S A++ +  +      L  P   
Sbjct: 510 IKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTH 569

Query: 879 RYI 881
           +++
Sbjct: 570 QHV 572



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/150 (20%), Positives = 62/150 (41%), Gaps = 6/150 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F  P+   +V EN    F   +   G P   V+W RN   +E   R+         +L
Sbjct: 464  PSFIEPLTKRKVYENTTLGFIVEV--EGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSL 521

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK----ASLQLESQHESALQKIQQLED 1826
             +  +   + G Y C A+N +GEA + + + +  +     +L     H+  ++   +   
Sbjct: 522  EISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHTT 581

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856
            SSR    +++ + V  + + + +     K+
Sbjct: 582  SSRTPSPQEIVLEVELSEKDVKEFEKQVKI 611



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 2233 EVEEPKIS--PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            E  EPK +  PP F+  L     V+E  T  F  +VE +  P   +++Y N   L+   R
Sbjct: 453  EAIEPKDNEMPPSFIEPLT-KRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDER 509

Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              +       SL+I +    + GEY   A+N +G   S  ++ +
Sbjct: 510  IKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 553



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 7/135 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F +E      V E   + F   VE  G P   + W+ N        R+         
Sbjct: 463  PPSF-IEPLTKRKVYENTTLGFIVEVE--GLPVPGVKWYRNKSLLEPDERIKMERVGNVC 519

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE--L 3811
            +L+I  I   + GEY C A N  G A + A +    + + V+   LP  ++ + + E  L
Sbjct: 520  SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVV--ALPPPVTHQHVMEFDL 577

Query: 3812 ERGRISDAPKEEPIV 3826
            E    S  P  + IV
Sbjct: 578  EHTTSSRTPSPQEIV 592



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 5/133 (3%)

Query: 3183 IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++WY N   +    RIK         L+I+  Q  + GEY+C A N  GE  + A ++  
Sbjct: 495  VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 554

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +    +    P +   + E +       +TPS     P + + +++   K V+      
Sbjct: 555  PQEERVVALPPPVTHQHVMEFDLEHTTSSRTPS-----PQEIVLEVELSEKDVKEFEKQV 609

Query: 3303 EARLVPVDDPDLK 3315
            +   VP   PD K
Sbjct: 610  KIVTVPDFTPDHK 622



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 6/130 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++PL+        +N  L   +E  G P   V+W+ N   +    R K        +
Sbjct: 464  PSFIEPLTKRKVY---ENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCS 520

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI---ERSDIVTDTQNEQAIEQIQLLED 1293
            L+I +    + GEY   AVN +G A + A V ++   ER   +      Q + +  L   
Sbjct: 521  LEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHT 580

Query: 1294 AARRTKQVRE 1303
             + RT   +E
Sbjct: 581  TSSRTPSPQE 590



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 7/144 (4%)

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            E  +P + E P   P F+  LT    + E     F   VE +  P   + W+ N   +  
Sbjct: 453  EAIEPKDNEMP---PSFIEPLTK-RKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEP 506

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
              R +        +L+I      + G YMC A N +GEA +   + +      ++    P
Sbjct: 507  DERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPP 566

Query: 2215 NGLEKIRQLEAQGHSTRIEVEEPK 2238
               + + + + + H+T      P+
Sbjct: 567  VTHQHVMEFDLE-HTTSSRTPSPQ 589



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F +P+   +V E   +     +  +  P   V+WY N   ++   R K        +L
Sbjct: 464  PSFIEPLTKRKVYENTTLGFIVEVEGL--PVPGVKWYRNKSLLEPDERIKMERVGNVCSL 521

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +I      + G YMC A N +GEA + ++V +
Sbjct: 522  EISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 553



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/97 (23%), Positives = 43/97 (44%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V+W ++   +E   RI         +L I ++   + G Y C A N IG+A + AN+ I+
Sbjct: 495  VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 554

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKI 1039
             +++ +     P   + +   +     S RT    +I
Sbjct: 555  PQEERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEI 591



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/59 (33%), Positives = 29/59 (49%)

Query: 3454 VEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            V+WY N   L+   R +         LEIS     + GEY+C A N  GEA + A++ +
Sbjct: 495  VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 553



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 44/180 (24%), Positives = 73/180 (40%), Gaps = 15/180 (8%)

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHF--ECRLIPVNDSSMRVEWFHNGKPL 3600
            GT +      ++  PP F    +   + EN++  F  E   +PV      V+W+ N   L
Sbjct: 449  GTPNEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG----VKWYRNKSLL 504

Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
                R+K         LEI  + + + G Y C A N  GEA     + +  ++  ++   
Sbjct: 505  EPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALP 564

Query: 3661 LPSHFKSGTESIQKLEETLHKR----EEITIEDE--KPNPPRFTVEIKDNIDVPEGGPVH 3714
             P   +   E    LE T   R    +EI +E E  + +   F  ++K  + VP+  P H
Sbjct: 565  PPVTHQHVMEF--DLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVK-IVTVPDFTPDH 621



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/51 (31%), Positives = 24/51 (47%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            V+WY N   L+   R          +L+I +    + G Y C A+N +GEA
Sbjct: 495  VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEA 545


>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
          Length = 1651

 Score =  105 bits (253), Expect = 3e-21
 Identities = 110/414 (26%), Positives = 161/414 (38%), Gaps = 48/414 (11%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI---KNSPDFQIHTFSTKS 4466
            PP   +      V + E A    + +G P P I+WY+    +   K+ P        + S
Sbjct: 67   PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 126

Query: 4467 ILIIRQVFVE----DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            +  +R V       D  V+  VA N  G A  S N  +E         I+   F     +
Sbjct: 127  LFFLRIVHGRKSRPDEGVYVCVARNYLGEA-VSHNASLEV-------AILRDDFRQNPSD 178

Query: 4523 VNVTSGQLVRLDTK-VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            V V  G+   ++ +   G     + W K+G  +  D   +I    G   L+I      D+
Sbjct: 179  VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG--KLMITYTRKSDA 235

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            GKY CV  N  GE   +   V  L   +             P  ++   +  V    + E
Sbjct: 236  GKYVCVGTNMVGERESE---VAELTVLE------------RPSFVKRPSNLAVTVDDSAE 280

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            F C+  G P+PTV+W K D  +  S+Y       D++TL+I +    D G Y CVA N  
Sbjct: 281  FKCEARGDPVPTVRWRKDDGELPKSRY----EIRDDHTLKIRKVTAGDMGSYTCVAENMV 336

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-- 4759
            G+   +A L V +P      P     RD VV  G+   F+ + T   +P I W REG+  
Sbjct: 337  GKAEASATLTVQEPPHFVVKP-----RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQN 391

Query: 4760 -LIPETP--DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L    P              L I N    D G + C+    AG + T A L V
Sbjct: 392  LLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 445



 Score =  100 bits (239), Expect = 1e-19
 Identities = 107/387 (27%), Positives = 161/387 (41%), Gaps = 50/387 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++  P+ +  D +I     K  L+I      D+  +  V  N  G  +  
Sbjct: 196  GHPEPTISWKKDGSPLDDK-DERITIRGGK--LMITYTRKSDAGKYVCVGTNMVGERESE 252

Query: 4496 -ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
             A L V E+          PSF     N+ VT         +  G     V W K+  ++
Sbjct: 253  VAELTVLER----------PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL 302

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R +I ++   +TL I +    D G Y CVA N  G+A   A   V  P        
Sbjct: 303  -PKSRYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEP-------- 350

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLI-------KPS 4666
                   P  +++P +D++VA G+ + F C+  G P P + W + G + +       + S
Sbjct: 351  -------PHFVVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSS 402

Query: 4667 KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ--PDQADNLPAL 4724
              F +S+T D   L I+     D G Y C   N AG +   A L+VT    D+   +   
Sbjct: 403  SRFSVSQTGD---LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ 459

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
             P+   V  +G         T    PTI W ++G L+  T D   I +  N VL I    
Sbjct: 460  GPVNQTVAVDG-TFVLSCVATGSPVPTILWRKDGVLV-STQD-SRIKQLENGVLQIRYAK 516

Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVVK 4811
              DTG +TC A+T +G+   SA + V+
Sbjct: 517  LGDTGRYTCIASTPSGEATWSAYIEVQ 543



 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 81/309 (26%), Positives = 128/309 (41%), Gaps = 31/309 (10%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F K+     V   + A F+ E  G+P+P ++W +++  +  S  ++I    T   L I
Sbjct: 262  PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHT---LKI 317

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            R+V   D   +  VAEN  G A+ SA L V+E          PP F +  ++  V  G+ 
Sbjct: 318  RKVTAGDMGSYTCVAENMVGKAEASATLTVQE----------PPHFVVKPRDQVVALGRT 367

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKK-----VQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            V    + TG     ++W + G +      QP   +       T  L I      D G Y 
Sbjct: 368  VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 427

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C  +N AG     A   V+     D+P P  +          P+   +  +G  +  SC 
Sbjct: 428  CQTLNVAGSIITKAYLEVT-DVIADRPPPVIRQG--------PVNQTVAVDGTFV-LSCV 477

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P+PT+ W K   L+  S      +  +   L+I  A   D G Y C+A   +G  T
Sbjct: 478  ATGSPVPTILWRKDGVLV--STQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 535

Query: 4706 VAAKLKVTQ 4714
             +A ++V +
Sbjct: 536  WSAYIEVQE 544



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 79/316 (25%), Positives = 119/316 (37%), Gaps = 39/316 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+I + P +  + +G  A    +  G P P + W+K G+R+                  
Sbjct: 67  PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERV------------------ 108

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
              T K D   + +L  + +   +   +     P E         Y+ +         + 
Sbjct: 109 --ETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA 166

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVN 443
           I    L   F +   D  V  G+    +C+   G P P ++W   D    DD + +I + 
Sbjct: 167 I----LRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWK-KDGSPLDDKDERITIR 221

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ-CRLNVIEKEQVVAPKFVERFSTLNV 502
                 LMIT    SD+G   CV  N  GE   +   L V+E+     P FV+R S L V
Sbjct: 222 GG---KLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLER-----PSFVKRPSNLAV 273

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              +       A G P P + W+KD    +P     I  D    TL I +  A D   Y 
Sbjct: 274 TVDDSAEFKCEARGDPVPTVRWRKDDGE-LPKSRYEIRDD---HTLKIRKVTAGDMGSYT 329

Query: 563 CTAQNVAGSTATRARL 578
           C A+N+ G     A L
Sbjct: 330 CVAENMVGKAEASATL 345



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 58/193 (30%), Positives = 89/193 (46%), Gaps = 13/193 (6%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR----DDYNHKI 440
           + ++   P+ V+   D  V++G+    +C+  GRP P + W+    ++     D  +H++
Sbjct: 61  LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 120

Query: 441 LVNESGNHALMITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498
           L+       L I +   S  D GV  CVARN  GE       N   +  ++   F +  S
Sbjct: 121 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH---NASLEVAILRDDFRQNPS 177

Query: 499 TLNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            + V  GEP V+  +   G P P I+W+KDG P+    E RI   GG   L I   + SD
Sbjct: 178 DVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDE-RITIRGG--KLMITYTRKSD 234

Query: 558 AAWYQCTAQNVAG 570
           A  Y C   N+ G
Sbjct: 235 AGKYVCVGTNMVG 247



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 62/206 (30%), Positives = 82/206 (39%), Gaps = 17/206 (8%)

Query: 380 EERIEISEKALA--PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
           E   E++E  +   P FVK   +  VT      F C   G P P V W  +D ++     
Sbjct: 248 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-R 306

Query: 438 HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
           ++I      +H L I  VT  D G  TCVA N  G+      L V E      P FV + 
Sbjct: 307 YEI----RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQE-----PPHFVVKP 357

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPII-----PNPELRIHTDGGASTLDIPR 552
               V  G  V     A G P P I W+++G   +     P       +      L I  
Sbjct: 358 RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITN 417

Query: 553 AKASDAAWYQCTAQNVAGSTATRARL 578
            + SD  +Y C   NVAGS  T+A L
Sbjct: 418 VQRSDVGYYICQTLNVAGSIITKAYL 443



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 66/290 (22%), Positives = 117/290 (40%), Gaps = 13/290 (4%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F +   N       +A+F+ + RG+P P V W +    L + ++Y +R      D +L
Sbjct: 262 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEIR-----DDHTL 315

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            I+++  GD G YTC A N  G+A  S  +  +                  + T + +A 
Sbjct: 316 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEAT 375

Query: 192 GTQGYTTEQSRQ-TQKVAYTNGTDHSSTDDFKVDTFEYRLLR----EVSFRESITKRYVG 246
           G         R+ +Q + ++     SS+      T +  +      +V +    T    G
Sbjct: 376 GNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAG 435

Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
               +   E+   +    PP I Q P N  +            +G+P P + W K+G  +
Sbjct: 436 SIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDG--V 493

Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
           + S +   I    +  L++R  +  D+G YT +A  P+G    S Y+ V+
Sbjct: 494 LVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 543



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 62/196 (31%), Positives = 86/196 (43%), Gaps = 19/196 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-IRDDY-----NHKILVNES 445
           P FV   +D+ V  G+   F C  TG P P + W     Q +   Y     + +  V+++
Sbjct: 351 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 410

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLN-- 501
           G+  L ITNV  SD G   C   N +G    +  L V +   V+A  P  V R   +N  
Sbjct: 411 GD--LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD---VIADRPPPVIRQGPVNQT 465

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-HTDGGASTLDIPRAKASDAAW 560
           V      VL+  A G+P P I W+KDGV ++   + RI   + G   L I  AK  D   
Sbjct: 466 VAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENG--VLQIRYAKLGDTGR 522

Query: 561 YQCTAQNVAGSTATRA 576
           Y C A   +G     A
Sbjct: 523 YTCIASTPSGEATWSA 538



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 100/435 (22%), Positives = 157/435 (36%), Gaps = 52/435 (11%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P +SW +  +PL + ++   R   + G   L+I      D G+Y C   N  GE 
Sbjct: 195 RGHPEPTISWKKDGSPLDDKDE---RITIRGG--KLMITYTRKSDAGKYVCVGTNMVGER 249

Query: 156 ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDH 215
              V                     +++ TV+  A   +     +      V +      
Sbjct: 250 ESEV-----AELTVLERPSFVKRPSNLAVTVDDSA---EFKCEARGDPVPTVRWRKDDGE 301

Query: 216 SSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNS 275
                +++       +R+V+  +  +   V E+ V    E   +L    PP    KPR+ 
Sbjct: 302 LPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVG-KAEASATLTVQEPPHFVVKPRDQ 360

Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNG-QRLINS----NKHEIITTHNHTTLRVRNTQK 330
            +  G    FQ + +GNP+P + W + G Q L+ S          +      L + N Q+
Sbjct: 361 VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQR 420

Query: 331 SDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKAL 390
           SD G+Y     N  G I+T  YL V       + D+    I      +T         A+
Sbjct: 421 SDVGYYICQTLNVAGSIITKAYLEV----TDVIADRPPPVIRQGPVNQT--------VAV 468

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
              FV  C    V  G            P P + W   D  +    + +I   E+G   L
Sbjct: 469 DGTFVLSC----VATGS-----------PVPTILW-RKDGVLVSTQDSRIKQLENG--VL 510

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I    L D+G  TC+A   SGE  +   + V E    V P    R +  N+    P   
Sbjct: 511 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQP---PRPTDPNLIPSAPSKP 567

Query: 511 NARAVGTPTPRITWQ 525
               V   T  ++WQ
Sbjct: 568 EVTDVSRNTVTLSWQ 582



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 75/310 (24%), Positives = 113/310 (36%), Gaps = 17/310 (5%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT- 126
           E  PP   +   +   ++G  A    K  G PTP + W  K    VE +K   R +    
Sbjct: 64  EDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWY-KGGERVETDKDDPRSHRMLL 122

Query: 127 GDVSLLIKQIGPG-----DEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRH 181
              SL   +I  G     DEG Y C ARN  GEA+                         
Sbjct: 123 PSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVA 182

Query: 182 VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
           V E    +    +G+        +  +  +  D   T         Y    +      + 
Sbjct: 183 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVG 242

Query: 242 KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
              VGE + +++      L  +  P   ++P N  +     A+F+ +  G+P P V W K
Sbjct: 243 TNMVGERESEVA-----ELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRK 297

Query: 302 NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTES 361
           +   L  S ++EI   H   TL++R     D G YT +AEN  G    S  L V+ P   
Sbjct: 298 DDGELPKS-RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPH- 352

Query: 362 YVQDQRSQYI 371
           +V   R Q +
Sbjct: 353 FVVKPRDQVV 362



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 77/308 (25%), Positives = 119/308 (38%), Gaps = 35/308 (11%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-----PDIRNKILEEDG 4567
            PP       ++ V+ G+   L+ K  G     + W K G++V+     P     +L    
Sbjct: 67   PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 126

Query: 4568 TYTLLILEAYPQ--DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             + L I+       D G Y CVA N  GEA       VS  A+        + A    + 
Sbjct: 127  LFFLRIVHGRKSRPDEGVYVCVARNYLGEA-------VSHNAS-------LEVAILRDDF 172

Query: 4626 IEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
             +   D +VA G+     C+   G P PT+ W K      P        T     L I+ 
Sbjct: 173  RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDG---SPLDDKDERITIRGGKLMITY 229

Query: 4685 AFPEDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                D G Y CV  N  G R +  A+L V +       P+     ++ V     A+FK +
Sbjct: 230  TRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPS-----NLAVTVDDSAEFKCE 284

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                  PT++W ++   +P++         ++  L I      D G++TC A    G+ E
Sbjct: 285  ARGDPVPTVRWRKDDGELPKS----RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAE 340

Query: 4804 TSAKLVVK 4811
             SA L V+
Sbjct: 341  ASATLTVQ 348



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 7/97 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-----IPNPELRI 539
           +++   P+ VE  S L V +GEP  LN +A G PTP I W K G  +      P     +
Sbjct: 62  RQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRML 121

Query: 540 HTDGGASTLDIPRAKAS--DAAWYQCTAQNVAGSTAT 574
              G    L I   + S  D   Y C A+N  G   +
Sbjct: 122 LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 158



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 91/354 (25%), Positives = 135/354 (38%), Gaps = 93/354 (26%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL---TVYGE 1912
            +S+G+ A   C+ E  P P   +EWY  G+ +++      S+     +  +     V+G 
Sbjct: 79   VSKGEPATLNCKAEGRPTPT--IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 136

Query: 1913 ----DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAV 1968
                D G Y C A N LG+AVS                 H ++LE +  L DD  +++  
Sbjct: 137  KSRPDEGVYVCVARNYLGEAVS-----------------HNASLE-VAILRDD--FRQNP 176

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
             D    V +P     +   +   GHP           +PT  + W  +G P+      + 
Sbjct: 177  SDVMVAVGEP----AVMECQPPRGHP-----------EPT--ISWKKDGSPLDDKDE-RI 218

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKI 2088
            T   G   L I Y    D G Y+C  TN VGE                       R  ++
Sbjct: 219  TIRGG--KLMITYTRKSDAGKYVCVGTNMVGE-----------------------RESEV 253

Query: 2089 QELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW-FH 2147
             EL   ERP  +      +RP  L            D A F+C  E   DP  T+ W   
Sbjct: 254  AELTVLERPSFV------KRPSNLAVTVD-------DSAEFKC--EARGDPVPTVRWRKD 298

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +G+  ++ +  R  H      L I    A D G+Y C A N +G+A  + TL V
Sbjct: 299  DGELPKSRYEIRDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 63/241 (26%), Positives = 84/241 (34%), Gaps = 18/241 (7%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE---NFPIKNSPDFQIHTFSTK 4465
            +PP F  K +   V       F+ E  G P P I W RE   N      P      FS  
Sbjct: 349  EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVS 408

Query: 4466 SI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523
                L I  V   D   +     N  G+    A L V +          PP       N 
Sbjct: 409  QTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR----PPPVIRQGPVNQ 464

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEAYPQDSG 4582
             V       L    TG+    + W K+G  V   D R K LE      L I  A   D+G
Sbjct: 465  TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG---VLQIRYAKLGDTG 521

Query: 4583 KYECVAINSAGEARCDAECVV---SLPATKDKPKPQTKAANAP--PEIIEPLKDKIVAEG 4637
            +Y C+A   +GEA   A   V    +P    +P       +AP  PE+ +  ++ +    
Sbjct: 522  RYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSW 581

Query: 4638 Q 4638
            Q
Sbjct: 582  Q 582



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 50/196 (25%), Positives = 78/196 (39%), Gaps = 24/196 (12%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA------SHRIRTV 3100
            PP       D++ +S+G+ A         G  +  IEW+  G+ +E       SHR+   
Sbjct: 67   PPRIVEHPSDLI-VSKGEPATLNCKA--EGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 123

Query: 3101 YAFGMVVLEILGTKTT-DSGTYSCRATNKWGQA---EISVKLECVDKSKGQKPRFTTHIQ 3156
                  +  + G K+  D G Y C A N  G+A     S+++  +     Q P       
Sbjct: 124  SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVM--- 180

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
                +  G+ A  EC   P   P+  I W  +G P+       T+     +   I YT+ 
Sbjct: 181  ----VAVGEPAVMECQP-PRGHPEPTISWKKDGSPLDDKDERITIRGGKLM---ITYTRK 232

Query: 3217 HDSGEYVCRAYNKYGE 3232
             D+G+YVC   N  GE
Sbjct: 233  SDAGKYVCVGTNMVGE 248



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 61/238 (25%), Positives = 94/238 (39%), Gaps = 48/238 (20%)

Query: 1700 HSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            H+A  EV      F     D+ VA  + A  E +  P G P+  + W ++G P++  +  
Sbjct: 159  HNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQP-PRGHPEPTISWKKDGSPLDDKDER 217

Query: 1760 TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
             T+       L + Y    D+G Y C   N +GE                     ES + 
Sbjct: 218  ITIRGG---KLMITYTRKSDAGKYVCVGTNMVGE--------------------RESEVA 254

Query: 1820 KIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879
            ++  LE  S  +R  ++ V V+ +  F                  E R +P P    R +
Sbjct: 255  ELTVLERPSFVKRPSNLAVTVDDSAEF----------------KCEARGDPVPTVRWRKD 298

Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               +G++ +S  RY   +D     L I  V   D G YTC A N +G+A +S  L VQ
Sbjct: 299  ---DGELPKS--RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 348



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/92 (32%), Positives = 38/92 (41%), Gaps = 4/92 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+  Q   N   A  G         G+P P + W RK   LV      ++   Q  +  
Sbjct: 454 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILW-RKDGVLVSTQDSRIK---QLENGV 509

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L I+    GD G YTC A    GEA  S YI+
Sbjct: 510 LQIRYAKLGDTGRYTCIASTPSGEATWSAYIE 541



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 9/114 (7%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN-GQPVTI 1489
            +++++ + +V  +P FV RP ++   ++     F+C  E   D    V W K+ G+    
Sbjct: 249  RESEVAELTVLERPSFVKRPSNLAVTVDDS-AEFKC--EARGDPVPTVRWRKDDGELPKS 305

Query: 1490 GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
             +  R  H      L I  + A D G YTC A N+VG  E S  LT +     V
Sbjct: 306  RYEIRDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV 354



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 9/96 (9%)

Query: 907  QKPEF-KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            ++P F K P    +++ +      EAR    GD    V W KD   +   SR     +  
Sbjct: 260  ERPSFVKRPSNLAVTVDDSAEFKCEAR----GDPVPTVRWRKDDGELP-KSRYEIRDDH- 313

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
               L I+ VT  D G YTC A N +G+A  SA LT+
Sbjct: 314  --TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 6/103 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   PS+L ++ + SA F+C      D    V W  +   L   SR +  +D     L
Sbjct: 262  PSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGEL-PKSRYEIRDDH---TL 315

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
            +I  V   D G YTC A N  G+A  S  L V+     +++P+
Sbjct: 316  KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPR 358



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 19/138 (13%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L+I      D G+Y+C A N  G+AE S  L     +  + P F    ++ + +  G++ 
Sbjct: 315  LKIRKVTAGDMGSYTCVAENMVGKAEASATL-----TVQEPPHFVVKPRD-QVVALGRTV 368

Query: 3168 HFECTVVPVDDPDMKIEWYHNG--------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
             F+C      +P   I W   G        QP + S+R  +VS  G   L I   Q  D 
Sbjct: 369  TFQCEA--TGNPQPAIFWRREGSQNLLFSYQPPQSSSRF-SVSQTG--DLTITNVQRSDV 423

Query: 3220 GEYVCRAYNKYGEDFTRA 3237
            G Y+C+  N  G   T+A
Sbjct: 424  GYYICQTLNVAGSIITKA 441



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 14/166 (8%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            P G     I W  +G  ++      T+    +++     T+ +D+G Y C  TN  G+ E
Sbjct: 194  PRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITY---TRKSDAGKYVCVGTNMVGERE 250

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
                 E  + +  ++P F     N+    D  SA F+C      DP   + W  +   + 
Sbjct: 251  ----SEVAELTVLERPSFVKRPSNLAVTVD-DSAEFKCEA--RGDPVPTVRWRKDDGELP 303

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
             S R +   D     L I      D G Y C A N  G+    AT+
Sbjct: 304  KS-RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATL 345



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 7/101 (6%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ + ++P F+         V+  SA F+   E + D   TV W  +  ++  + R +  
Sbjct: 255  ELTVLERPSFVKRPSNLAVTVD-DSAEFKC--EARGDPVPTVRWRKDDGELPKS-RYEIR 310

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             D     L I  V A D G YT VA N  G+A+ SA++TV+
Sbjct: 311  DDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 348



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 1698 QRHSAQDEV-ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
            +R S   E+ + + P F     ++ V  + +A F+      GDP   V W ++   +  S
Sbjct: 248  ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGELPKS 305

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
             R     D     L ++ V   D G+YTC A N +G+A  S+TL VQ
Sbjct: 306  -RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 348



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 6/101 (5%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F+ +  +  V   +   F+C  E + DP   + W ++   LP   RY    D    +L
Sbjct: 262  PSFVKRPSNLAVTVDDSAEFKC--EARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TL 315

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
             I  V A D G Y C A N  G+    AT++ ++ P  +++
Sbjct: 316  KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVK 356



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+   +N+     D+  F+C  E   DP   + W  ++  LP  +RY+   D +   L I
Sbjct: 264  FVKRPSNLAVTVDDSAEFKC--EARGDPVPTVRWRKDDGELPK-SRYEIRDDHT---LKI 317

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                  D G YTC A N  G A  S +L
Sbjct: 318  RKVTAGDMGSYTCVAENMVGKAEASATL 345



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 13/105 (12%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASSR 684
           V  PP F+V  +      G  + F+   E  G+P   I W + G        Q  ++SSR
Sbjct: 347 VQEPPHFVVKPRDQVVALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQSSSR 404

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           F S+ + G   L + ++   D G Y C+ ++  G   TKA L VT
Sbjct: 405 F-SVSQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT 446



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 9/79 (11%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-----MTISHVR 2442
            + +G+ A  +C+    G PT  +EW++  + +E      ++H     S     + I H R
Sbjct: 79   VSKGEPATLNCKA--EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 136

Query: 2443 DE--DEGVYMCRASNLLGE 2459
                DEGVY+C A N LGE
Sbjct: 137  KSRPDEGVYVCVARNYLGE 155



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 9/107 (8%)

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN-GKPIKT 1355
            R  +V E +TV++ P F +   N+      +   +C  +  GD    V W  + G+  K+
Sbjct: 249  RESEVAE-LTVLERPSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGELPKS 305

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +  R     D   L +  V   D G YTC A N +G+A  S  L V
Sbjct: 306  RYEIR-----DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 7/97 (7%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLV----ECNKYSMRYN-EQ 125
           PP F    ++   A G    F+ +  GNP P + W R+ +  +    +  + S R++  Q
Sbjct: 350 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 409

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           TGD  L I  +   D G Y C   N  G  I   Y++
Sbjct: 410 TGD--LTITNVQRSDVGYYICQTLNVAGSIITKAYLE 444



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/116 (30%), Positives = 48/116 (41%), Gaps = 14/116 (12%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK--LL-----PSGHRY 3878
            V  PP F+ + +   V     V F+C  E   +P+  I W R G   LL     P     
Sbjct: 347  VQEPPHFVVKPRDQVVALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQSSSR 404

Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVP 3934
             +V   G   L I  V   D G YIC+ +N  G   TKA +   ++ D+I     P
Sbjct: 405  FSVSQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYL---EVTDVIADRPPP 455



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 4/74 (5%)

Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNL 2722
            E + E R DP   + W K+   L   +R +   D    TL I  +   D G YTC A N+
Sbjct: 280  EFKCEARGDPVPTVRWRKDDGELPK-SRYEIRDDH---TLKIRKVTAGDMGSYTCVAENM 335

Query: 2723 LGEAVSTASIKIED 2736
            +G+A ++A++ +++
Sbjct: 336  VGKAEASATLTVQE 349



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLR------- 2708
            +G+   L  + E R  P   IEW+K G  + T      +    L + S+  LR       
Sbjct: 81   KGEPATLNCKAEGRPTPT--IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 138

Query: 2709 NDDSGIYTCKATNLLGEAVS-TASIKI 2734
              D G+Y C A N LGEAVS  AS+++
Sbjct: 139  RPDEGVYVCVARNYLGEAVSHNASLEV 165



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 15/91 (16%)

Query: 4074 DSQLPKHMKSIE-----KIREMEA----SWQVTPEQVVEESKARC------PPVFVSLPD 4118
            D +LPK    I      KIR++ A    S+    E +V +++A        PP FV  P 
Sbjct: 299  DGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPR 358

Query: 4119 AVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
               V  G    F C  TG+P+P + W   G+
Sbjct: 359  DQVVALGRTVTFQCEATGNPQPAIFWRREGS 389



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 2/74 (2%)

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
            F    +  G P   + W ++GV +   +      + G   L ++Y    D+G YTC A  
Sbjct: 472  FVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIAST 529

Query: 1790 ELGEAVTSSTLFVQ 1803
              GEA  S+ + VQ
Sbjct: 530  PSGEATWSAYIEVQ 543



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 7/107 (6%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P FV+  SN   V+   +   +C  E  GDP   V W  +   +   SR++   D    
Sbjct: 261  RPSFVKRPSNLA-VTVDDSAEFKC--EARGDPVPTVRWRKDDGELPK-SRYEIRDDH--- 313

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
             L I   T+ D G YT  A N +G A  SA + V E    V   +++
Sbjct: 314  TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQ 360



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 11/107 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTL--- 3747
            PPR  VE   ++ V +G P   +C+ E  G PT  I+W+  G    T     R H +   
Sbjct: 67   PPRI-VEHPSDLIVSKGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLP 123

Query: 3748 -NDFGFIALDIDYIYARDAGEYTCRATNKWGSATT-TAKITCSAKRD 3792
                 F+ +        D G Y C A N  G A +  A +  +  RD
Sbjct: 124  SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRD 170



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT------GSRVKTIN 3610
            PP     PSDLI+S+   A   C+       +  +EW+  G+ + T        R+   +
Sbjct: 67   PPRIVEHPSDLIVSKGEPATLNCK--AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 124

Query: 3611 DFGFVILEIGGVYQR-DAGLYTCKATNRHGEA 3641
               F +  + G   R D G+Y C A N  GEA
Sbjct: 125  GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEA 156



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 5/82 (6%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   +E Q  PR  P   I W K+G  L      + T   G   L I   R  D+G Y 
Sbjct: 184  GEPAVMECQ-PPRGHPEPTISWKKDGSPLDDKDE-RITIRGG--KLMITYTRKSDAGKYV 239

Query: 2717 CKATNLLGEAVS-TASIKIEDR 2737
            C  TN++GE  S  A + + +R
Sbjct: 240  CVGTNMVGERESEVAELTVLER 261



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            E    ECQ  P G P   + W  +G PL  K+    I   G + + +      D+G+Y+C
Sbjct: 185  EPAVMECQ-PPRGHPEPTISWKKDGSPLDDKDERITIRG-GKLMITY--TRKSDAGKYVC 240

Query: 4049 RATNLYGMDETK-AVIKTTGKPGIV 4072
              TN+ G  E++ A +    +P  V
Sbjct: 241  VGTNMVGERESEVAELTVLERPSFV 265



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-----GYVALDILYTY 2175
            + +G+ A   C+ E    P  TI+W+  G+++        +H           L I++  
Sbjct: 79   VSKGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 136

Query: 2176 AE--DSGTYMCKATNKLGEAV-NTCTLKVA 2202
                D G Y+C A N LGEAV +  +L+VA
Sbjct: 137  KSRPDEGVYVCVARNYLGEAVSHNASLEVA 166



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 10/92 (10%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT------GHRFR-PAYEFDYVALDLLSVY 1376
            +G    L C+ +  G  T  +EW+  G+ ++T       HR   P+    ++ +      
Sbjct: 81   KGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 138

Query: 1377 PEDSGVYTCQATNQLGEAVT-SCALRVIAKKD 1407
              D GVY C A N LGEAV+ + +L V   +D
Sbjct: 139  RPDEGVYVCVARNYLGEAVSHNASLEVAILRD 170


>BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein
            protein.
          Length = 1263

 Score =  105 bits (251), Expect = 5e-21
 Identities = 110/421 (26%), Positives = 164/421 (38%), Gaps = 28/421 (6%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129
            PP F +     +  +     F  ++ G P P V W R K+ L    +  M   E+ G+V 
Sbjct: 841  PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKM---ERVGNVC 897

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEA--ICSVYIQPEGXXXXXXXXXXXXXYRHVSE--- 184
            SL I  I  G+ GEY C A N  GEA    +V I P+              ++HV E   
Sbjct: 898  SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQ--EERVVALPPPVTHQHVMEFDL 955

Query: 185  --TVEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
              T   +    Q    E     + V  +       +  +F  D     +  +V     + 
Sbjct: 956  EHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPDHKSMIVSLDVLPFNFVD 1015

Query: 242  KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
                         +ID  +  + PP+      + K+ E +DA F+  + G P P V W+K
Sbjct: 1016 PNMDSREGEDKELKIDLEVFEM-PPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYK 1074

Query: 302  NGQRLINSN-KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
                +   N K+ I       TL++RN   SDS  Y   A N  G  +  G+L +     
Sbjct: 1075 EYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEI 1134

Query: 361  SYVQDQRSQYITDTQQRE-------TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
              V  ++S+    +   E       T+   E       P+F+K   D     G    F C
Sbjct: 1135 FAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC 1194

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN--HALMITNVTLSDSGVVTCVARNKS 471
             V G P P V W+ + + ++     +  V ESG   H L IT++  SD G   CVA NKS
Sbjct: 1195 LVRGSPRPTVYWYKDGKLVQ---GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKS 1251

Query: 472  G 472
            G
Sbjct: 1252 G 1252



 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 71/236 (30%), Positives = 110/236 (46%), Gaps = 10/236 (4%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMH 1763
            EV    P F MP+ D ++ EN  A F+  +I +  P+  V+W +  + IE  N +     
Sbjct: 1033 EVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISE 1090

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV-QSKASLQLESQHESALQKI- 1821
            + G   L ++ V   DS TY CRA+N +GEA+    L +  S+    +  + +  L  + 
Sbjct: 1091 EKGSYTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLM 1150

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            ++L   S Y         V   PRFI  ++       G +A+++C +   P P   V WY
Sbjct: 1151 EELVLKSNYTDSFFEFQVVEGPPRFIKGISD-CYAPIGTAAYFQCLVRGSPRPT--VYWY 1207

Query: 1882 FNGKVLQSGHRYRTSND-FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +GK++Q G R+       GF  L I ++   D GEY C A N  G A S   L +
Sbjct: 1208 KDGKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 1262



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 105/467 (22%), Positives = 175/467 (37%), Gaps = 46/467 (9%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP   +     K+ E     F V++ G P P V W++N   L    + ++    N  +L 
Sbjct: 841  PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLE 900

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
            + N QK + G Y   A N  G   +   + +  P E  V          T Q   E  +E
Sbjct: 901  ISNIQKGEGGEYMCHAVNIIGEAKSFANVDI-MPQEERVVALPPPV---THQHVMEFDLE 956

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
             +  +  P   ++  + +++E  +  F+ +V     PE T                    
Sbjct: 957  HTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFT-------------------- 996

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETA-FQCRLNVIEKEQVVAPKFVERFSTLNVR 503
              +H  MI ++ +     V     ++ GE    +  L V E    + P+F+       + 
Sbjct: 997  -PDHKSMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFE----MPPRFIMPICDFKIP 1051

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQ 562
            E    V     +G PTP + W K+ + I P N +  I  + G+ TL I     SD+A Y+
Sbjct: 1052 ENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDSATYR 1111

Query: 563  CTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERAR 622
            C A N  G    R  L            K+  +   + +            +        
Sbjct: 1112 CRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFF------- 1164

Query: 623  PYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEAS 682
                  E   V  PP+FI  +    A  G   +F+  +   G P   + W K+G+ ++  
Sbjct: 1165 ------EFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVR--GSPRPTVYWYKDGKLVQGR 1216

Query: 683  SRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
                     G+ +L + SL   D GEY C A + +G+AE+ A L +T
Sbjct: 1217 RFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 1263



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 66/228 (28%), Positives = 95/228 (41%), Gaps = 27/228 (11%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD-IRNKILEEDGTYT 4570
            +PP F +   +  +           V G    +V W K    ++PD I+  I EE G+YT
Sbjct: 1037 MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSYT 1096

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARC-------DAECVVSLPATKDKPKPQT------- 4616
            L I      DS  Y C A+N  GEA C       D+E + ++ A K K    +       
Sbjct: 1097 LKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSE-IFAVIAKKSKVTLSSLMEELVL 1155

Query: 4617 -----------KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
                       +    PP  I+ + D     G A  F C + G P PTV WYK  KL++ 
Sbjct: 1156 KSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQG 1215

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
             ++         + L I+     DEG+Y+CVA N +G     A L +T
Sbjct: 1216 RRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 1263



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 102/454 (22%), Positives = 172/454 (37%), Gaps = 58/454 (12%)

Query: 4396 TQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP 4455
            T    +E P     PP F + +   +V+E+    F VE +G P+P +KWYR    ++  P
Sbjct: 828  TPNEAIE-PKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLE--P 884

Query: 4456 DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
            D +I      ++          S   + + +  GG   C A  ++ E +      I+P  
Sbjct: 885  DERIKMERVGNVC---------SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQE 935

Query: 4516 FTLTAQNVNVTSGQLVRLDTKVTGTK--PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
              + A    VT   ++  D + T +   P     +   +  + D++    E +    ++ 
Sbjct: 936  ERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLEVELSEKDVK----EFEKQVKIVT 991

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
            +  +  D  K   V+++       D   + S      + K   +    PP  I P+ D  
Sbjct: 992  VPEFTPDH-KSMIVSLDVLPFNFVDPN-MDSREGEDKELKIDLEVFEMPPRFIMPICDFK 1049

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY-FQMSRTADEYTLRISEAFPEDEGD 4692
            + E     F C ++G P P V+WYK    I+P    + +S     YTL+I      D   
Sbjct: 1050 IPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDSAT 1109

Query: 4693 YKCVAYNSAGR---------------VTVAAKLKVTQPDQADNLPALTPLRD----IVVY 4733
            Y+C A N  G                  +A K KVT     + L   +   D      V 
Sbjct: 1110 YRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVV 1169

Query: 4734 EGQP----------------AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN-A 4776
            EG P                A F+  +    +PT+ W ++G L+ +   F +   G    
Sbjct: 1170 EGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRRFTVEESGTGFH 1228

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L I +  + D G + C AT  +G  E+ A L +
Sbjct: 1229 NLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 1262



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 73/288 (25%), Positives = 118/288 (40%), Gaps = 17/288 (5%)

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
            T  + T   K  IV    LP       +   E G   +   +  +   PP+FI  I    
Sbjct: 991  TVPEFTPDHKSMIVSLDVLPFNFVDPNMDSRE-GEDKELKIDLEVFEMPPRFIMPICDFK 1049

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSGHRYRTVYDMGFVSLDILYVYAEDS 3899
            + E+    F+C V     P+  ++WY+    + P   +Y    + G  +L I  V   DS
Sbjct: 1050 IPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDS 1107

Query: 3900 GEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYL 3959
              Y CRAVN  GE   +  ++   + D  +   + +  K + +    E  +K   ++ + 
Sbjct: 1108 ATYRCRAVNCVGEAICRGFLT---MGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFF 1164

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
                 + V  + PPRF+  I    + +      F+C +   G P   V W+ +GK L+  
Sbjct: 1165 E----FQV-VEGPPRFIKGISDCYAPIG-TAAYFQCLVR--GSPRPTVYWYKDGK-LVQG 1215

Query: 4020 NRFT-PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
             RFT      G+  +    +   D GEY C ATN  GM E+ A +  T
Sbjct: 1216 RRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 1263



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 60/228 (26%), Positives = 99/228 (43%), Gaps = 8/228 (3%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASS-RFTSIFRFGYI 694
            PP+FI+P+      E     F+  +  +G PT +++W K    IE  + ++      G  
Sbjct: 1038 PPRFIMPICDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSY 1095

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPE-TLQYI-QQLED 752
            +L + ++ + DS  Y CRAV+  G A  +  L +         ++  + TL  + ++L  
Sbjct: 1096 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 1155

Query: 753  YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
             S Y       +     P+FI+ + D      G  A+F+  +     PT  V WYKDG+ 
Sbjct: 1156 KSNYTDSFFEFQVVEGPPRFIKGISDC-YAPIGTAAYFQCLVRGSPRPT--VYWYKDGKL 1212

Query: 813  ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            +            G+ +L I  L   D G Y   A NK G A S A++
Sbjct: 1213 VQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 1260



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 63/230 (27%), Positives = 100/230 (43%), Gaps = 9/230 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYV 967
            P F  PI D   I E   A F+  +  IG  T  V+W K+   +E  + +       G  
Sbjct: 1039 PRFIMPICD-FKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSY 1095

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK--DIIAESQHPGGLEKIQYLED 1025
             L I++V + D+  Y CRA N +G+A     LT+   +   +IA+         ++ L  
Sbjct: 1096 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 1155

Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQ 1085
             S Y+    E   +   PRF+  +      + G +A+F+  V  +     TV WY +GK 
Sbjct: 1156 KSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLV--RGSPRPTVYWYKDGKL 1212

Query: 1086 ITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +            G+  L I S+   D G Y  VA N +G A+  A++T+
Sbjct: 1213 VQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 1262



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 67/235 (28%), Positives = 96/235 (40%), Gaps = 16/235 (6%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI--NDFGF 3614
            PP F     D  + ENS A F+C +I +   +  V+W+      +    +K +   + G 
Sbjct: 1038 PPRFIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYM-CIEPDNIKYVISEEKGS 1094

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ--GIILEPQLPSHFKSGTESI 3672
              L+I  V   D+  Y C+A N  GEA     L +   +   +I +    +      E +
Sbjct: 1095 YTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELV 1154

Query: 3673 QKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWF 3732
             K   T    E   +E     PPRF   I D    P G   +F C V   G P   + W+
Sbjct: 1155 LKSNYTDSFFEFQVVE----GPPRFIKGISDCY-APIGTAAYFQCLVR--GSPRPTVYWY 1207

Query: 3733 HNGRPFATGSRVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             +G+    G R        GF  L I  +   D GEY C ATNK G A + A +T
Sbjct: 1208 KDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALT 1261



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 89/331 (26%), Positives = 136/331 (41%), Gaps = 32/331 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI---EASHRIRTVYAF-----GMVV-LEI 3110
            + E  + H  +S  P+  Q +V+E   + K +   E   +I TV  F      M+V L++
Sbjct: 950  VMEFDLEHTTSSRTPS-PQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPDHKSMIVSLDV 1008

Query: 3111 LGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            L     D    S    +K    E+ + LE  +      PRF   I + + + +   A F+
Sbjct: 1009 LPFNFVDPNMDSREGEDK----ELKIDLEVFE----MPPRFIMPICDFK-IPENSDAVFK 1059

Query: 3171 CTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEYVCRAYNK 3229
            C+V+ +  P++K  WY     +        +S+  G   L I      DS  Y CRA N 
Sbjct: 1060 CSVIGIPTPEVK--WYKEYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNC 1117

Query: 3230 YGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE----PPKFI 3285
             GE   R  +   G   ++    +   +     +E L      T S    +    PP+FI
Sbjct: 1118 VGEAICRGFLTM-GDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFI 1176

Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD-FGIVILDI 3344
              I D    + G +A+F+  LV    P   V W+ +GK L  G R+       G   L I
Sbjct: 1177 KGISDCYAPI-GTAAYFQC-LVR-GSPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFI 1232

Query: 3345 LYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
                + + GEY CVATNK G   + A L  T
Sbjct: 1233 TSLVKSDEGEYRCVATNKSGMAESFAALTLT 1263



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 63/235 (26%), Positives = 99/235 (42%), Gaps = 15/235 (6%)

Query: 2363 KRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE-D 2421
            K  +I   V    P F  P+ +   I E   A F C +I  G PT +V+W++    IE D
Sbjct: 1026 KELKIDLEVFEMPPRFIMPICDF-KIPENSDAVFKCSVI--GIPTPEVKWYKEYMCIEPD 1082

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHP 2481
            + +   + + G  ++ I +V   D   Y CRA N +GE                +  +  
Sbjct: 1083 NIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAK-- 1140

Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIF---TQVLTGPSELWE--GQHAHYEARVVPVG 2536
            +    +  L +    +S   D  FE  +     + + G S+ +   G  A+++  V   G
Sbjct: 1141 KSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLV--RG 1198

Query: 2537 DPSLRFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
             P     WY +G +L  G RF       GF  L I S+V +D G Y C A N++G
Sbjct: 1199 SPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 1252



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 56/232 (24%), Positives = 99/232 (42%), Gaps = 7/232 (3%)

Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGS-RFTETN 1630
            EV    P     + + +I E   A F+  +I +   T +V+WY     ++  + ++  + 
Sbjct: 1033 EVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIP--TPEVKWYKEYMCIEPDNIKYVISE 1090

Query: 1631 NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG-IAIVHSKKSIYLESQHEGALPRL- 1688
              G   L I +    DS TY CRA+N +GEA+  G + +  S+    +  + +  L  L 
Sbjct: 1091 EKGSYTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLM 1150

Query: 1689 NQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748
             +L   S Y     + +V+   P F   + D       AA+F+   +  G P+  V W +
Sbjct: 1151 EELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC--LVRGSPRPTVYWYK 1208

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
            +G  ++           G+  L +  +   D G Y C A N+ G A + + L
Sbjct: 1209 DGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 1260



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 60/233 (25%), Positives = 101/233 (43%), Gaps = 22/233 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH-RFKTTYDFGYVA 2036
            P+F  PI + ++ E      + ++  +  PT  V+WY     ++  + ++  + + G   
Sbjct: 1039 PRFIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYMCIEPDNIKYVISEEKGSYT 1096

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAV-----TTSSVKVDA----KSGLYLDTLDEQRLKK 2087
            L I      D+ TY C+A N VGEA+     T    ++ A    KS + L +L E+ + K
Sbjct: 1097 LKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLK 1156

Query: 2088 IQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH 2147
                + +   + +E       P F+  ++       G  A+F+C V     P  T+ W+ 
Sbjct: 1157 SNYTDSFFEFQVVEGP-----PRFIKGISDC-YAPIGTAAYFQCLVR--GSPRPTVYWYK 1208

Query: 2148 NGQKIRAGHRYRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
            +G K+  G R+       G+  L I      D G Y C ATNK G A +   L
Sbjct: 1209 DG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 1260



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 60/232 (25%), Positives = 96/232 (41%), Gaps = 12/232 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH-RYRTTHDFGYV 2167
            P F+  +   + + E   A F+C V  I  P   + W+     I   + +Y  + + G  
Sbjct: 1039 PRFIMPICDFK-IPENSDAVFKCSVIGIPTPE--VKWYKEYMCIEPDNIKYVISEEKGSY 1095

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR--NIILDTQHPNGLEKIRQLEA 2225
             L I      DS TY C+A N +GEA+    L +       +I           + +L  
Sbjct: 1096 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 1155

Query: 2226 QGHSTRIEVEEPKI-SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKA 2284
            + + T    E   +  PPRF+  +    +   G  A+F+C V     P   + +Y +GK 
Sbjct: 1156 KSNYTDSFFEFQVVEGPPRFIKGI-SDCYAPIGTAAYFQCLVR--GSPRPTVYWYKDGKL 1212

Query: 2285 LQSAARFHI-TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
            +Q   RF +     G+ +L I   V  D GEY   A N  G   S  ++T+T
Sbjct: 1213 VQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 1263



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 51/238 (21%), Positives = 105/238 (44%), Gaps = 10/238 (4%)

Query: 2224 EAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGK 2283
            E +    +I++E  ++ PPRF+  +     + E   A F+C V  +  P   +++Y    
Sbjct: 1022 EGEDKELKIDLEVFEM-PPRFIMPICDFK-IPENSDAVFKCSVIGIPTPE--VKWYKEYM 1077

Query: 2284 ALQ-SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH--CTSAISMTVTAKGSI 2340
             ++    ++ I+ + G  +L I++    D+  Y  +A+N +G   C   ++M  +   ++
Sbjct: 1078 CIEPDNIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAV 1137

Query: 2341 ISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRL 2400
            I++  +      + EL     +        V    P F + + +      G  A+F C  
Sbjct: 1138 IAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDC-YAPIGTAAYFQC-- 1194

Query: 2401 IPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            +  G P   V W+++ KL++      +    G+ ++ I+ +   DEG Y C A+N  G
Sbjct: 1195 LVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 1252



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 62/232 (26%), Positives = 102/232 (43%), Gaps = 16/232 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYVSLD 2834
            FI  + +    E  +  F+C+V     PT +++W+     + P   +Y  + +    +L 
Sbjct: 1041 FIMPICDFKIPENSDAVFKCSVIGI--PTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLK 1098

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I +    DS  Y C+A N  G A   G L   GD  I F     + K  L ++   EE  
Sbjct: 1099 IRNVCLSDSATYRCRAVNCVGEAICRGFLTM-GDSEI-FAVIAKKSKVTLSSL--MEELV 1154

Query: 2895 LAKGRRPSVPDTEYPK--PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            L      S  + +  +  P +I  I+  +  + G   + +  V  +  P   + WY +GK
Sbjct: 1155 LKSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLV--RGSPRPTVYWYKDGK 1211

Query: 2953 VLEQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRG--EAFTSSTV 3001
            ++ QG RF +  S  GF  L +  + + D G Y C A NK G  E+F + T+
Sbjct: 1212 LV-QGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 1262



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 61/237 (25%), Positives = 96/237 (40%), Gaps = 14/237 (5%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
            K+  I  E   + PRF+  P     + E     F+C +  +    +K  W+K    +   
Sbjct: 1026 KELKIDLEVFEMPPRFIM-PICDFKIPENSDAVFKCSVIGIPTPEVK--WYKEYMCIEPD 1082

Query: 1491 H-RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR-LTCRSTTDIVRSTQN 1548
            + ++    + G   L I ++   DS  Y CRAVN VG  E  CR       ++I      
Sbjct: 1083 NIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVG--EAICRGFLTMGDSEIFAVIAK 1140

Query: 1549 EAGLEQIQVLED---RSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVS 1605
            ++ +    ++E+   +S Y  +    +V    P     + +     G  A+F+   +   
Sbjct: 1141 KSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQ--CLVRG 1198

Query: 1606 DATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
                 V WY + K L  G RFT E +  GF  L I S +  D G Y C A N  G A
Sbjct: 1199 SPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 1254



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 12/225 (5%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFRTFCDFGFV 3478
            P F +P+ + + + E  +A F+  +     P +K  WY     ++  + ++    + G  
Sbjct: 1039 PRFIMPICDFK-IPENSDAVFKCSVIGIPTPEVK--WYKEYMCIEPDNIKYVISEEKGSY 1095

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAAL 3538
             L+I      DS  Y CRA N  GEA+    + +       + ++  K    ++ +   L
Sbjct: 1096 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVL 1155

Query: 3539 EGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGK 3598
            +  S   D+         PP F    SD      ++A+F+C  +        V W+ +GK
Sbjct: 1156 K--SNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQC--LVRGSPRPTVYWYKDGK 1211

Query: 3599 PLLTGSRVKTIND--FGFVILEIGGVYQRDAGLYTCKATNRHGEA 3641
             L+ G R  T+ +   GF  L I  + + D G Y C ATN+ G A
Sbjct: 1212 -LVQGRRF-TVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 1254



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 59/243 (24%), Positives = 102/243 (41%), Gaps = 13/243 (5%)

Query: 1299 KQVREDITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            K+++ D+ V + P +F   + + +  E ++   +C +  +G  T  V+W+     I+  +
Sbjct: 1026 KELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDN 1083

Query: 1358 -RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
             ++  + E     L + +V   DS  Y C+A N +GEA+    L  +   ++       S
Sbjct: 1084 IKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL-TMGDSEIFAVIAKKS 1142

Query: 1417 GLEKIQYLED---TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTD 1473
             +     +E+    S Y  +    + V   PRF+         I G   +F+C +     
Sbjct: 1143 KVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLVR--GS 1199

Query: 1474 SNLKVEWFKNGQPVTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
                V W+K+G+ V  G RF       G+  L I  L+  D G Y C A N  G  E   
Sbjct: 1200 PRPTVYWYKDGKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFA 1258

Query: 1533 RLT 1535
             LT
Sbjct: 1259 ALT 1261



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 48/201 (23%), Positives = 80/201 (39%), Gaps = 9/201 (4%)

Query: 2672 PNLKIEWFKNGVTLTT-GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P  +++W+K  + +     +   + + G  TL I ++   DS  Y C+A N +GEA+   
Sbjct: 1066 PTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVGEAICRG 1125

Query: 2731 SIKIEDRHWLL----GESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCK 2786
             + + D            +   SL     L                   FI  +++    
Sbjct: 1126 FLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAP 1185

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSLDITHTYEEDSGI 2845
             G   +F+C V  S  PT  + W+ + K L  G R+      + + +L IT   + D G 
Sbjct: 1186 IGTAAYFQCLVRGSPRPT--VYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGE 1242

Query: 2846 YTCKATNSKGSATTSGSLRCT 2866
            Y C ATN  G A +  +L  T
Sbjct: 1243 YRCVATNKSGMAESFAALTLT 1263



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 21/205 (10%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI- 694
            PP FI PL      E   + F   +E  G P   ++W +N   +E   R   + R G + 
Sbjct: 841  PPSFIEPLTKRKVYENTTLGFIVEVE--GLPVPGVKWYRNKSLLEPDERI-KMERVGNVC 897

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYS 754
            SL++ ++   + GEY C AV+  G A++ A + + P+         P T Q++ + +   
Sbjct: 898  SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFD--- 954

Query: 755  KYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT 814
                   +E  TS R    + +    EL E     FE Q+  V+ P    E+  D + + 
Sbjct: 955  -------LEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVP----EFTPDHKSMI 1003

Query: 815  ASSRITSIFNFGYVSLNIMHLRAED 839
             S     +  F +V  N+     ED
Sbjct: 1004 VS---LDVLPFNFVDPNMDSREGED 1025



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 5/107 (4%)

Query: 2355 ELESAEPFKRP-EIPEPVTRQRPV-FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEW 2412
            E+  ++ F  P E  EP   + P  F +PL     + E  T  F   +   G P   V+W
Sbjct: 819  EIWRSDSFGTPNEAIEPKDNEMPPSFIEPLTK-RKVYENTTLGFIVEV--EGLPVPGVKW 875

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +RN+ L+E   RI         S+ IS+++  + G YMC A N++GE
Sbjct: 876  YRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGE 922



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 49/204 (24%), Positives = 80/204 (39%), Gaps = 8/204 (3%)

Query: 2535 VGDPSLRFEWYINGVELKMGS-RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXX 2593
            +G P+   +WY   + ++  + ++  + + G  TL I +V  +D+  Y C+A+N  G   
Sbjct: 1063 IGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVGEAI 1122

Query: 2594 XXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAM--NKVPEMFVDTGVQQAPIFTTHLKSY 2651
                            A + +      ++E  +  N     F    V+  P F   +   
Sbjct: 1123 CRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDC 1182

Query: 2652 DKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRND 2710
               + G   Y +  V  R  P   + W+K+G  L  G R        G   L I SL   
Sbjct: 1183 YAPI-GTAAYFQCLV--RGSPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKS 1238

Query: 2711 DSGIYTCKATNLLGEAVSTASIKI 2734
            D G Y C ATN  G A S A++ +
Sbjct: 1239 DEGEYRCVATNKSGMAESFAALTL 1262



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP FI  +    V E+  + F   VE    P   ++WYRN  LL    R +        S
Sbjct: 841  PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDERIKMERVGNVCS 898

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L+I  +   + GEY+C AVN  GE
Sbjct: 899  LEISNIQKGEGGEYMCHAVNIIGE 922



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 4/112 (3%)

Query: 381 ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
           E IE  +  + P F++    R V E     F   V G P P V W+ N   +  D   +I
Sbjct: 831 EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPD--ERI 888

Query: 441 LVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI-EKEQVVA 490
            +   GN  +L I+N+   + G   C A N  GE      ++++ ++E+VVA
Sbjct: 889 KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVA 940



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 2/107 (1%)

Query: 1834 EDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
            E +E   N+ P    +     K+ E  +  +   +E  P P   V+WY N  +L+   R 
Sbjct: 831  EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDERI 888

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            +        +L+I  +   + GEY C A+N +G+A S   +++  +E
Sbjct: 889  KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQE 935



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 47/195 (24%), Positives = 74/195 (37%), Gaps = 7/195 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKN-RFTPIYDF 4028
            + PPRF+  I     + E     F+C +  +G P  +V+W+     +   N ++    + 
Sbjct: 1036 EMPPRFIMPI-CDFKIPENSDAVFKCSV--IGIPTPEVKWYKEYMCIEPDNIKYVISEEK 1092

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIR 4088
            G   +    V   DS  Y CRA N  G    +  + T G   I +     K   ++  + 
Sbjct: 1093 GSYTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL-TMGDSEI-FAVIAKKSKVTLSSLM 1150

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            E         +   E      PP F+          G  A F C V G P+P V W  +G
Sbjct: 1151 EELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDG 1210

Query: 4149 NTIVNGSRYKLTYDG 4163
              +V G R+ +   G
Sbjct: 1211 K-LVQGRRFTVEESG 1224



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 48/197 (24%), Positives = 78/197 (39%), Gaps = 11/197 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGS-RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P  +++WY     +E  + ++ ++ + G  TL + +V   DS  Y C+A N  GEA    
Sbjct: 1066 PTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVGEAICRG 1125

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDD---TGRPPEFTTVFKD 3056
              + T  D+ I      K    L  +  +E+ + K        +      PP F     D
Sbjct: 1126 --FLTMGDSEIFAVIAKKSKVTLSSL--MEELVLKSNYTDSFFEFQVVEGPPRFIKGISD 1181

Query: 3057 IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTT 3116
                  G  A+++   +  G     + W+ +GK ++           G   L I     +
Sbjct: 1182 CY-APIGTAAYFQC--LVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKS 1238

Query: 3117 DSGTYSCRATNKWGQAE 3133
            D G Y C ATNK G AE
Sbjct: 1239 DEGEYRCVATNKSGMAE 1255



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 62/230 (26%), Positives = 94/230 (40%), Gaps = 17/230 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN-RIQTYHDFGYV 1101
            PRF+ P+    KI E   A F+  V      T  V+WY     I   N +     + G  
Sbjct: 1039 PRFIMPICDF-KIPENSDAVFKCSVIGIP--TPEVKWYKEYMCIEPDNIKYVISEEKGSY 1095

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEE-- 1159
             L I +V   DS  Y   A N  GEA     +T+   S I      +     +  +EE  
Sbjct: 1096 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGD-SEIFAVIAKKSKVTLSSLMEELV 1154

Query: 1160 --SKFVEPMYQIEEISKSKPVFVQPLSNP-PPVSEGKNIHLECRLEPMGDPTMRVEWFHN 1216
              S + +  ++ + + +  P F++ +S+   P+  G   + +C +   G P   V W+ +
Sbjct: 1155 LKSNYTDSFFEFQVV-EGPPRFIKGISDCYAPI--GTAAYFQCLVR--GSPRPTVYWYKD 1209

Query: 1217 GRSVTVGSRFKTYYD-FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
            G+ V  G RF       GF  L I     +D GEY   A N  G A + A
Sbjct: 1210 GKLVQ-GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFA 1258



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +   +     G  A F+  +RG+P P V W  K   LV+  ++++     TG  +
Sbjct: 1172 PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWY-KDGKLVQGRRFTVE-ESGTGFHN 1229

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEA 155
            L I  +   DEGEY C A N+ G A
Sbjct: 1230 LFITSLVKSDEGEYRCVATNKSGMA 1254



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 20/94 (21%), Positives = 40/94 (42%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
           K+  + P F+E  +   V E   +       G P P + W ++   + P+  +++   G 
Sbjct: 836 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 895

Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +L+I   +  +   Y C A N+ G   + A +
Sbjct: 896 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 929



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 2/82 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K+ E   +    +VE    P +K  W++N   L    R+K      + +L I++++  + 
Sbjct: 852  KVYENTTLGFIVEVEGLPVPGVK--WYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEG 909

Query: 2713 GIYTCKATNLLGEAVSTASIKI 2734
            G Y C A N++GEA S A++ I
Sbjct: 910  GEYMCHAVNIIGEAKSFANVDI 931



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 4/97 (4%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            D E P P +I P+  + ++ E   L    +VE    P +K  WY N  +LE   R K+  
Sbjct: 837  DNEMP-PSFIEPLT-KRKVYENTTLGFIVEVEGLPVPGVK--WYRNKSLLEPDERIKMER 892

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
                 +L++ ++ + + G Y C A N  GEA + + V
Sbjct: 893  VGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 929



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 4/123 (3%)

Query: 760 ESIEEQTSQRP-QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
           E+IE + ++ P  FI PL    ++ E     F  ++  +  P   V+WY++   +    R
Sbjct: 831 EAIEPKDNEMPPSFIEPLTKR-KVYENTTLGFIVEVEGL--PVPGVKWYRNKSLLEPDER 887

Query: 819 ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQR 878
           I         SL I +++  + G Y   AVN +GEA S A++ +  +      L  P   
Sbjct: 888 IKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTH 947

Query: 879 RYI 881
           +++
Sbjct: 948 QHV 950



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/150 (20%), Positives = 62/150 (41%), Gaps = 6/150 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F  P+   +V EN    F   +   G P   V+W RN   +E   R+         +L
Sbjct: 842  PSFIEPLTKRKVYENTTLGFIVEV--EGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSL 899

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK----ASLQLESQHESALQKIQQLED 1826
             +  +   + G Y C A+N +GEA + + + +  +     +L     H+  ++   +   
Sbjct: 900  EISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHTT 959

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856
            SSR    +++ + V  + + + +     K+
Sbjct: 960  SSRTPSPQEIVLEVELSEKDVKEFEKQVKI 989



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 2233 EVEEPKIS--PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            E  EPK +  PP F+  L     V+E  T  F  +VE +  P   +++Y N   L+   R
Sbjct: 831  EAIEPKDNEMPPSFIEPLT-KRKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEPDER 887

Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              +       SL+I +    + GEY   A+N +G   S  ++ +
Sbjct: 888  IKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 931



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 5/133 (3%)

Query: 3183 IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            ++WY N   +    RIK         L+I+  Q  + GEY+C A N  GE  + A ++  
Sbjct: 873  VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 932

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
             +    +    P +   + E +       +TPS     P + + +++   K V+      
Sbjct: 933  PQEERVVALPPPVTHQHVMEFDLEHTTSSRTPS-----PQEIVLEVELSEKDVKEFEKQV 987

Query: 3303 EARLVPVDDPDLK 3315
            +   VP   PD K
Sbjct: 988  KIVTVPEFTPDHK 1000



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 7/135 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F +E      V E   + F   VE  G P   + W+ N        R+         
Sbjct: 841  PPSF-IEPLTKRKVYENTTLGFIVEVE--GLPVPGVKWYRNKSLLEPDERIKMERVGNVC 897

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE--L 3811
            +L+I  I   + GEY C A N  G A + A +    + + V+   LP  ++ + + E  L
Sbjct: 898  SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVV--ALPPPVTHQHVMEFDL 955

Query: 3812 ERGRISDAPKEEPIV 3826
            E    S  P  + IV
Sbjct: 956  EHTTSSRTPSPQEIV 970



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 6/130 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++PL+        +N  L   +E  G P   V+W+ N   +    R K        +
Sbjct: 842  PSFIEPLTKRKVY---ENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCS 898

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI---ERSDIVTDTQNEQAIEQIQLLED 1293
            L+I +    + GEY   AVN +G A + A V ++   ER   +      Q + +  L   
Sbjct: 899  LEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHT 958

Query: 1294 AARRTKQVRE 1303
             + RT   +E
Sbjct: 959  TSSRTPSPQE 968



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 7/144 (4%)

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            E  +P + E P   P F+  LT    + E     F   VE +  P   + W+ N   +  
Sbjct: 831  EAIEPKDNEMP---PSFIEPLTK-RKVYENTTLGFIVEVEGLPVPG--VKWYRNKSLLEP 884

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
              R +        +L+I      + G YMC A N +GEA +   + +      ++    P
Sbjct: 885  DERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPP 944

Query: 2215 NGLEKIRQLEAQGHSTRIEVEEPK 2238
               + + + + + H+T      P+
Sbjct: 945  VTHQHVMEFDLE-HTTSSRTPSPQ 967



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F +P+   +V E   +     +  +  P   V+WY N   ++   R K        +L
Sbjct: 842  PSFIEPLTKRKVYENTTLGFIVEVEGL--PVPGVKWYRNKSLLEPDERIKMERVGNVCSL 899

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +I      + G YMC A N +GEA + ++V +
Sbjct: 900  EISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 931



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 15/180 (8%)

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHF--ECRLIPVNDSSMRVEWFHNGKPL 3600
            GT +      ++  PP F    +   + EN++  F  E   +PV      V+W+ N   L
Sbjct: 827  GTPNEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPG----VKWYRNKSLL 882

Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
                R+K         LEI  + + + G Y C A N  GEA     + +  ++  ++   
Sbjct: 883  EPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALP 942

Query: 3661 LPSHFKSGTESIQKLEETLHKR----EEITIEDE--KPNPPRFTVEIKDNIDVPEGGPVH 3714
             P   +   E    LE T   R    +EI +E E  + +   F  ++K  + VPE  P H
Sbjct: 943  PPVTHQHVMEF--DLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVK-IVTVPEFTPDH 999



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/97 (23%), Positives = 43/97 (44%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V+W ++   +E   RI         +L I ++   + G Y C A N IG+A + AN+ I+
Sbjct: 873  VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 932

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKI 1039
             +++ +     P   + +   +     S RT    +I
Sbjct: 933  PQEERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEI 969



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/59 (33%), Positives = 29/59 (49%)

Query: 3454 VEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            V+WY N   L+   R +         LEIS     + GEY+C A N  GEA + A++ +
Sbjct: 873  VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 931



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/51 (31%), Positives = 24/51 (47%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            V+WY N   L+   R          +L+I +    + G Y C A+N +GEA
Sbjct: 873  VKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEA 923


>AK056336-1|BAB71154.1|  512|Homo sapiens protein ( Homo sapiens cDNA
            FLJ31774 fis, clone NT2RI2008050, weakly similar to
            BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
            CORE ).
          Length = 512

 Score =  105 bits (251), Expect = 5e-21
 Identities = 109/413 (26%), Positives = 169/413 (40%), Gaps = 41/413 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFST--KS 4466
            PP+F ++     +             G P P IKW R +N PI + P F + + S     
Sbjct: 133  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRP-FSVSSISQLRTG 191

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L I  ++  D   +   AEN+ G  +    + V         G+V P   ++    NV 
Sbjct: 192  ALFILNLWASDKGTYICEAENQFGKIQSETTVTVT--------GLVAPLIGISPSVANVI 243

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ + L   +    PI +  W+KN   +   ++N  +      +L I     QD G+Y 
Sbjct: 244  EGQQLTLPCTLLAGNPIPERRWIKNSAML---LQNPYITVRSDGSLHIERVQLQDGGEYT 300

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG        VV +  T    +          +I+  +      EG  +   CK
Sbjct: 301  CVASNVAGTNNKTTSVVVHVLPTIQHGQ----------QILSTI------EGIPVTLPCK 344

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P P+V W K  +LI  S   + S  AD  +L +     E+ G+Y C A N+AG   
Sbjct: 345  ASGNPKPSVIWSKKGELISTSSA-KFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYAK 402

Query: 4706 VAAKLKV-TQPDQADNLPALTPLR--DIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +L V  +P    +   L+  +  +I V  G+      ++ S   P I W +E  LI 
Sbjct: 403  RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS 462

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            P +P    +  G+   + I  T   D+G + C AT  AG V  + KL V  ++
Sbjct: 463  PFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHGES 512



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 73/243 (30%), Positives = 103/243 (42%), Gaps = 25/243 (10%)

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            TL I  A P+D+G Y C+A NSAG                DK     +   AP +++   
Sbjct: 6    TLFIKNAAPKDAGIYGCLASNSAGT---------------DKQNSTLRYIEAP-KLMVVQ 49

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
             + +VA G      CK  G P P V+W+KGD  ++PS +  +        L+I E    D
Sbjct: 50   SELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG--LLKIQETQDLD 107

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749
             GDY CVA N AGR T    L V  P      PA     D+ +  G        +    +
Sbjct: 108  AGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA-----DVSMEIGSNVTLPCYVQGYPE 162

Query: 4750 PTIQWLR-EGALIPETP-DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            PTI+W R +   I   P     I +     L I N +  D GT+ C A    G++++   
Sbjct: 163  PTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETT 222

Query: 4808 LVV 4810
            + V
Sbjct: 223  VTV 225



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 88/347 (25%), Positives = 143/347 (41%), Gaps = 39/347 (11%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I+    +D+ ++  +A N  GT K ++ L   E           P   +    + V  
Sbjct: 7    LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEA----------PKLMVVQSELLVAL 56

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL-ILEAYPQDSGKYEC 4586
            G +  ++ K +G  P  V W K   +++P   +  L  D    LL I E    D+G Y C
Sbjct: 57   GDITVMECKTSGIPPPQVKWFKGDLELRP---STFLIIDPLLGLLKIQETQDLDAGDYTC 113

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VAIN AG A                    T    +PP  I+   D  +  G  +   C +
Sbjct: 114  VAINEAGRATGKI----------------TLDVGSPPVFIQEPADVSMEIGSNVTLPCYV 157

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT--LRISEAFPEDEGDYKCVAYNSAGRV 4704
             G P PT++W + D +   S+ F +S  +   T  L I   +  D+G Y C A N  G+ 
Sbjct: 158  QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGK- 216

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK-TQITSKIKPTIQWLREGALIPE 4763
             + ++  VT       L  ++P    V+ EGQ      T +     P  +W++  A++ +
Sbjct: 217  -IQSETTVTVTGLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 274

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             P   +  +G+   L I     +D G +TC A+  AG    +  +VV
Sbjct: 275  NPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV 318



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 91/384 (23%), Positives = 148/384 (38%), Gaps = 41/384 (10%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  G P P +KW++ +  ++ S    I       +L I++    D+  +  VA N  G
Sbjct: 63   ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAG 120

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--L 4548
             A     L V            PP F     +V++  G  V L   V G     + W  L
Sbjct: 121  RATGKITLDVGS----------PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL 170

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
             N            + +  T  L IL  +  D G Y C A N  G+ + +    V+    
Sbjct: 171  DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT---- 226

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSK 4667
                        AP   I P    ++ EGQ +   C ++ G P+P  +W K   ++  + 
Sbjct: 227  ---------GLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 276

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y  +     + +L I     +D G+Y CVA N AG       + V        LP +   
Sbjct: 277  YITV---RSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV------HVLPTIQHG 327

Query: 4728 RDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + I+   EG P     + +   KP++ W ++G LI  +        G +  L + +   E
Sbjct: 328  QQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI--STSSAKFSAGADGSLYVVSPGGE 385

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            ++G + C AT  AG  +   +L V
Sbjct: 386  ESGEYVCTATNTAGYAKRKVQLTV 409



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P F++   D  +  G      C V G P P + W  +++  I         +++    AL
Sbjct: 134 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 193

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I N+  SD G   C A N+ G+   +  + V     +VAP      S  NV EG+ + L
Sbjct: 194 FILNLWASDKGTYICEAENQFGKIQSETTVTV---TGLVAPLIGISPSVANVIEGQQLTL 250

Query: 511 NARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               + G P P   W K+   ++ NP + + +DG   +L I R +  D   Y C A NVA
Sbjct: 251 PCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVA 307

Query: 570 GS 571
           G+
Sbjct: 308 GT 309



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 12/201 (5%)

Query: 402 DVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
           +V EG+     C +  G P PE  W  N   +    N  I V   G+  L I  V L D 
Sbjct: 241 NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ--NPYITVRSDGS--LHIERVQLQDG 296

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
           G  TCVA N +G T  +    V+     V P        L+  EG PV L  +A G P P
Sbjct: 297 GEYTCVASNVAG-TNNKTTSVVVH----VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP 351

Query: 521 RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYX 580
            + W K G  +I     +  + G   +L +      ++  Y CTA N AG    + +L  
Sbjct: 352 SVIWSKKG-ELISTSSAKF-SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 409

Query: 581 XXXXXXXXXQKRLHLPRPTKV 601
                    Q+ L   +P ++
Sbjct: 410 YVRPRVFGDQRGLSQDKPVEI 430



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 52/182 (28%), Positives = 81/182 (44%), Gaps = 10/182 (5%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP+ + V  +  V  G +T  +C+ +G P P+V WF  D ++R       L+ +     L
Sbjct: 42  APKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLL 98

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I      D+G  TCVA N++G    +  L+V        P F++  + +++  G  V L
Sbjct: 99  KIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEIGSNVTL 153

Query: 511 NARAVGTPTPRITWQK-DGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
                G P P I W++ D +PI   P  +   +      L I    ASD   Y C A+N 
Sbjct: 154 PCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQ 213

Query: 569 AG 570
            G
Sbjct: 214 FG 215



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 47/178 (26%), Positives = 74/178 (41%), Gaps = 10/178 (5%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           EG      C+ +G P P V W      I    + K      G+  L + +    +SG   
Sbjct: 335 EGIPVTLPCKASGNPKPSVIWSKKGELISTS-SAKFSAGADGS--LYVVSPGGEESGEYV 391

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPK---FVERFSTLNVREGEPVVLNARAVGTPTPR 521
           C A N +G    + +L V  + +V   +     ++   ++V  GE V L       P P 
Sbjct: 392 CTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI 451

Query: 522 ITWQKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           ITW K+   I P +P    HT   + ++ I   + SD+  Y C A N+AG+     +L
Sbjct: 452 ITWAKETQLISPFSPR---HTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKL 506



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 7/129 (5%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I N    D+G+  C+A N +G       L  IE     APK +   S L V  G+  V
Sbjct: 7   LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITV 61

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           +  +  G P P++ W K  + + P+  L I  D     L I   +  DA  Y C A N A
Sbjct: 62  MECKTSGIPPPQVKWFKGDLELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEA 119

Query: 570 GSTATRARL 578
           G    +  L
Sbjct: 120 GRATGKITL 128



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 30/204 (14%)

Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
           EG       + SGNP+P V W K G+ +  S+     +     +L V +    +SG Y  
Sbjct: 335 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVC 392

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
            A N      T+GY   +     YV   R +   D +    ++ +EIS            
Sbjct: 393 TATN------TAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEIS------------ 431

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
               V  G+     C V   P P +TW   + Q+   ++ +     SG+  + IT    S
Sbjct: 432 ----VLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFSPRHTFLPSGS--MKITETRTS 484

Query: 459 DSGVVTCVARNKSGETAFQCRLNV 482
           DSG+  CVA N +G      +LNV
Sbjct: 485 DSGMYLCVATNIAGNVTQAVKLNV 508



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 24/85 (28%), Positives = 37/85 (43%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           SPP+F Q   +     G N      ++G P P + W R     +    +S+    Q    
Sbjct: 132 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 191

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           +L I  +   D+G Y C A NQ+G+
Sbjct: 192 ALFILNLWASDKGTYICEAENQFGK 216



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 6/137 (4%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L+I  T+  D+G Y+C A N+ G+A   + L+      G  P F     ++  ++ G +
Sbjct: 97   LLKIQETQDLDAGDYTCVAINEAGRATGKITLDV-----GSPPVFIQEPADVS-MEIGSN 150

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C V    +P +K     N         + ++S      L I      D G Y+C A
Sbjct: 151  VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEA 210

Query: 3227 YNKYGEDFTRATINCYG 3243
             N++G+  +  T+   G
Sbjct: 211  ENQFGKIQSETTVTVTG 227



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V +PP FI +    ++E    V   C V+   +P ++     N  +        ++  + 
Sbjct: 130  VGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 189

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +L IL ++A D G YIC A N FG+  ++ T++
Sbjct: 190  TGALFILNLWASDKGTYICEAENQFGKIQSETTVT 224



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 63/269 (23%), Positives = 96/269 (35%), Gaps = 22/269 (8%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A G     E K  G P P V W +    L       +  +   G   L I++    D G+
Sbjct: 55  ALGDITVMECKTSGIPPPQVKWFKGDLELRPST--FLIIDPLLG--LLKIQETQDLDAGD 110

Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGY---TTEQ 200
           YTC A N+ G A   + +                    +   V    Y  QGY   T + 
Sbjct: 111 YTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTLPCY-VQGYPEPTIKW 167

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQ---ISTEID 257
            R      ++     SS    +        L  ++   S    Y+ E++ Q   I +E  
Sbjct: 168 RRLDNMPIFSRPFSVSSISQLRTGA-----LFILNLWASDKGTYICEAENQFGKIQSETT 222

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKNGQRLINSNKHEIIT 316
            ++  +  P I   P  + + EG        L +GNP P   W KN   L+   ++  IT
Sbjct: 223 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLL---QNPYIT 279

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             +  +L +   Q  D G YT +A N  G
Sbjct: 280 VRSDGSLHIERVQLQDGGEYTCVASNVAG 308



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 13/191 (6%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW--FYNGKTIEASHRIRTV 3100
            D G PP F    ++  D+S    ++        G     I+W    N         + ++
Sbjct: 129  DVGSPPVF---IQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 185

Query: 3101 YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG 3160
                   L IL    +D GTY C A N++G+    ++ E      G          ++  
Sbjct: 186  SQLRTGALFILNLWASDKGTYICEAENQFGK----IQSETTVTVTGLVAPLIGISPSVAN 241

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
            + +GQ     CT++   +P  +  W  N   +  +  I   SD     L I   Q  D G
Sbjct: 242  VIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGG 297

Query: 3221 EYVCRAYNKYG 3231
            EY C A N  G
Sbjct: 298  EYTCVASNVAG 308



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            ++ N+ EGQ     C L+  G+P  +  W +N  ++  +  IT   D    S+ I  V+ 
Sbjct: 238  SVANVIEGQQLTLPCTLL-AGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQL 293

Query: 2444 EDEGVYMCRASNLLG 2458
            +D G Y C ASN+ G
Sbjct: 294  QDGGEYTCVASNVAG 308



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 84/380 (22%), Positives = 149/380 (39%), Gaps = 41/380 (10%)

Query: 1175 SKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S PVF+Q    P  VS   G N+ L C ++   +PT++     N    +      +    
Sbjct: 132  SPPVFIQ---EPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL 188

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS--AHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
               AL I++  ++D G Y   A N  G   + T+  V  +    I         IE  QL
Sbjct: 189  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 248

Query: 1291 -LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLE-CRLQPVGDQTMRVEWFC 1348
             L         + E   +  +    +  +     +G+ +H+E  +LQ  G+ T       
Sbjct: 249  TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCVASNVA 307

Query: 1349 --NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT---------NQLGEAVTS 1397
              N K         P  +     L  +   P       C+A+         ++ GE +++
Sbjct: 308  GTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV---TLPCKASGNPKPSVIWSKKGELIST 364

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYL---EDTSRYKKTDIIDESVTIKPRF------VT 1448
             + +  A  D  L    P G E  +Y+    +T+ Y K  +   +V ++PR       ++
Sbjct: 365  SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKV-QLTVYVRPRVFGDQRGLS 423

Query: 1449 RPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDI 1506
            + K +E +V+ G+ V   C+++ +      + W K  Q ++    F P H F    ++ I
Sbjct: 424  QDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQLIS---PFSPRHTFLPSGSMKI 478

Query: 1507 IDLIAEDSGIYTCRAVNLVG 1526
             +    DSG+Y C A N+ G
Sbjct: 479  TETRTSDSGMYLCVATNIAG 498



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 1/101 (0%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + + V   P FI Q      +  G +    C ++ YP+P ++     N  +        +
Sbjct: 126  ITLDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS 184

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +     AL IL ++  D G Y C+A N  G+  S   + V
Sbjct: 185  ISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 225



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G+P   + W K G+ I  SS   S    G  SL ++S   ++SGEY C A +  G A+ K
Sbjct: 347 GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRK 404

Query: 724 AVL--HVTPR 731
             L  +V PR
Sbjct: 405 VQLTVYVRPR 414



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 7/134 (5%)

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
            TL I  A P+D G Y C+A NSAG     + L+  +  +      +    +++V  G   
Sbjct: 6    TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-----LMVVQSELLVALGDIT 60

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              + + +    P ++W +    +   P   +I +    +L I  T + D G +TC A   
Sbjct: 61   VMECKTSGIPPPQVKWFKGD--LELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINE 118

Query: 4799 AGQVETSAKLVVKS 4812
            AG+      L V S
Sbjct: 119  AGRATGKITLDVGS 132



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA--VSATGVAE 721
           G+P  +  W+KN   +   + + ++   G + ++ + L  QD GEYTC A  V+ T    
Sbjct: 257 GNPIPERRWIKNSAML-LQNPYITVRSDGSLHIERVQL--QDGGEYTCVASNVAGTNNKT 313

Query: 722 TKAVLHVTPRATIERTSQHPETLQYI 747
           T  V+HV P  TI+   Q   T++ I
Sbjct: 314 TSVVVHVLP--TIQHGQQILSTIEGI 337



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 11/134 (8%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D+G Y C A+N  G  + +  L  ++  K         +Q+   +  G     EC    +
Sbjct: 16   DAGIYGCLASNSAGTDKQNSTLRYIEAPK------LMVVQSELLVALGDITVMECKTSGI 69

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P +K  W+     +R ST +  + D    +L I  TQ+ D+G+Y C A N+ G    +
Sbjct: 70   PPPQVK--WFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK 125

Query: 3237 ATINCYGKGGVYLE 3250
             T++  G   V+++
Sbjct: 126  ITLD-VGSPPVFIQ 138



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP F  E  D + +  G  V   C V+   +PT++     N   F+    V +++    
Sbjct: 132  SPPVFIQEPAD-VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 190

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             AL I  ++A D G Y C A N++G   +   +T
Sbjct: 191  GALFILNLWASDKGTYICEAENQFGKIQSETTVT 224



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P+  V W   G+++ +     ++   G  +L +++  GE+SGEY
Sbjct: 335  EGIPVTLPCKASGNPKPS--VIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 390

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
             C A N  G A   ++L V  +  +  D +
Sbjct: 391  VCTATNTAGYAKRKVQLTVYVRPRVFGDQR 420



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           K  GNP P V W+ KK  L+  +  S +++    D SL +   G  + GEY CTA N  G
Sbjct: 344 KASGNPKPSVIWS-KKGELISTS--SAKFSAGA-DGSLYVVSPGGEESGEYVCTATNTAG 399

Query: 154 EA----ICSVYIQP 163
            A      +VY++P
Sbjct: 400 YAKRKVQLTVYVRP 413



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            EG PV   C+    G+P   + W   G   +T S   +    G  +L +      ++GEY
Sbjct: 335  EGIPVTLPCKAS--GNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEY 390

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C ATN  G A    ++T    R  V   Q  +G+S +K  E+      +      + S 
Sbjct: 391  VCTATNTAGYAKRKVQLTVYV-RPRVFGDQ--RGLSQDKPVEISVLAGEEVTLPCEVKSL 447

Query: 3829 PPKFITQIK 3837
            PP  IT  K
Sbjct: 448  PPPIITWAK 456



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + +A R T ++  D+     P F +   ++    G+NV L C +Q   + T++     N 
Sbjct: 116  INEAGRATGKITLDVG--SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 173

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                         +    AL +L+++  D G Y C+A NQ G+  +   + V
Sbjct: 174  PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 225



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW--FHNGQKIRAGHRYRTTHD 2163
            G  PVF+     + +++ G      C V+   +P  TI W    N           +   
Sbjct: 131  GSPPVFIQEPADV-SMEIGSNVTLPCYVQGYPEP--TIKWRRLDNMPIFSRPFSVSSISQ 187

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                AL IL  +A D GTY+C+A N+ G+  +  T+ V G
Sbjct: 188  LRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 227



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 10/109 (9%)

Query: 1452 SIENVIEGQHVHFECKL---EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            S+ NVIEGQ +   C L    P+ +      W KN   + + + +  +   G + ++ + 
Sbjct: 238  SVANVIEGQQLTLPCTLLAGNPIPERR----WIKNSA-MLLQNPYITVRSDGSLHIERVQ 292

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            L  +D G YTC A N+ GT+  +  +       I    Q  + +E I V
Sbjct: 293  L--QDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 339



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           SPP   Q+P +  ++ G++      + G P P + W +     I S    + +     T 
Sbjct: 132 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 191

Query: 323 -LRVRNTQKSDSGHYTLLAENPNGCI 347
            L + N   SD G Y   AEN  G I
Sbjct: 192 ALFILNLWASDKGTYICEAENQFGKI 217



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+ +  +     ++ G     EC+    P P  +V+W F G +      +   +    
Sbjct: 41   EAPKLMV-VQSELLVALGDITVMECKTSGIPPP--QVKW-FKGDLELRPSTFLIIDPL-L 95

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              L I      D+G+YTC AIN  G+A   I L+V S    I++
Sbjct: 96   GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQE 139



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP   +   ++ VA       E +    G P  +V+W +  + +  S  L      G  
Sbjct: 41   EAPKLMVVQSELLVALGDITVMECKTS--GIPPPQVKWFKGDLELRPSTFLIIDPLLGL- 97

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             L ++     D+G YTC AINE G A    TL V S
Sbjct: 98   -LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 132



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/93 (24%), Positives = 37/93 (39%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI    ++  + G N+   C V+   +PT+K     N           S       +L 
Sbjct: 135  VFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF 194

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I + +  D G Y C+A N  G   +  ++  TG
Sbjct: 195  ILNLWASDKGTYICEAENQFGKIQSETTVTVTG 227



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 43/173 (24%), Positives = 70/173 (40%), Gaps = 10/173 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            +G+    + W   G+ I  S    +  A G   L ++     +SG Y C ATN  G A+ 
Sbjct: 346  SGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVCTATNTAGYAKR 403

Query: 3135 SVKLECVDKSK--GQKPRFTTHIQNIE-GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
             V+L    + +  G + R  +  + +E  +  G+     C V  +  P   I W    Q 
Sbjct: 404  KVQLTVYVRPRVFGDQ-RGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI--ITWAKETQL 460

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244
            +   +   T    G   + I  T+  DSG Y+C A N  G       +N +G+
Sbjct: 461  ISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHGE 511



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           +  PK+        +  G     + + SG P P+V WFK    L  S    +I       
Sbjct: 40  IEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTF--LIIDPLLGL 97

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           L+++ TQ  D+G YT +A N  G       L V SP
Sbjct: 98  LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP 133



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PPVF+  P  V++E G      C V G+P+P + W
Sbjct: 133  PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW 167



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+     S+L+++       EC+   +     +V+WF     L   + +  I D    +L
Sbjct: 43   PKLMVVQSELLVALGDITVMECKTSGIPPP--QVKWFKGDLELRPSTFL--IIDPLLGLL 98

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I      DAG YTC A N  G AT    L V      I EP
Sbjct: 99   KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEP 140



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/94 (25%), Positives = 40/94 (42%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP FI     V+   G  +     ++   +PT+K   L N          +SI +    +
Sbjct: 133 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 192

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           L +L+L   D G Y C A +  G  +++  + VT
Sbjct: 193 LFILNLWASDKGTYICEAENQFGKIQSETTVTVT 226



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            +P   V W   G+ +   S +F    D    +  +SP   E+SGEY+C A N  G A   
Sbjct: 348  NPKPSVIWSKKGELISTSSAKFSAGADGSLYV--VSPG-GEESGEYVCTATNTAGYAKRK 404

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
              + V  +  +  +    +G+  + DK   +   +G   TL  E +S  PP  T      
Sbjct: 405  VQLTVYVRPRVFGDQ---RGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQ 459

Query: 3568 ILSENSSAH 3576
            ++S  S  H
Sbjct: 460  LISPFSPRH 468



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 16/37 (43%), Positives = 21/37 (56%)

Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGD 2868
            S+ IT T   DSG+Y C ATN  G+ T +  L   G+
Sbjct: 475  SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHGE 511


>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
          Length = 1551

 Score =  104 bits (249), Expect = 9e-21
 Identities = 109/414 (26%), Positives = 162/414 (39%), Gaps = 45/414 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI---KNSPDFQIHTFSTKS 4466
            PP   +      V + E A    + +G P P I+WY+    +   K+ P        + S
Sbjct: 28   PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 87

Query: 4467 ILIIRQVFVE----DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            +  +R V       D  V+  VA N  G A  S N  +E         I+   F     +
Sbjct: 88   LFFLRIVHGRKSRPDEGVYVCVARNYLGEA-VSHNASLEV-------AILRDDFRQNPSD 139

Query: 4523 VNVTSGQLVRLDTK-VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            V V  G+   ++ +   G     + W K+G  +  D   +I    G   L+I      D+
Sbjct: 140  VMVVVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG--KLMITYTRKSDA 196

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            GKY CV  N  GE   +   V  L   +             P  ++   +  V    + E
Sbjct: 197  GKYVCVGTNMVGERESE---VAELTVLE------------RPSFVKRPSNLAVTVDDSAE 241

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            F C+  G P+PTV+W K D  +  S+Y       D++TL+I +    D G Y CVA N  
Sbjct: 242  FKCEARGDPVPTVRWRKDDGELPKSRY----EIRDDHTLKIRKVTAGDMGSYTCVAENMV 297

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-- 4759
            G+   +A L V    +  +   + P RD VV  G+   F+ + T   +P I W REG+  
Sbjct: 298  GKAEASATLTVQVGSEPPHF-VVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQN 355

Query: 4760 -LIPETP--DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L    P              L I N    D G + C+    AG + T A L V
Sbjct: 356  LLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 409



 Score =  103 bits (246), Expect = 2e-20
 Identities = 106/387 (27%), Positives = 160/387 (41%), Gaps = 47/387 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++  P+ +  D +I     K  L+I      D+  +  V  N  G  +  
Sbjct: 157  GHPEPTISWKKDGSPLDDK-DERITIRGGK--LMITYTRKSDAGKYVCVGTNMVGERESE 213

Query: 4496 -ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
             A L V E+          PSF     N+ VT         +  G     V W K+  ++
Sbjct: 214  VAELTVLER----------PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL 263

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R +I ++   +TL I +    D G Y CVA N  G+A   A   V +         
Sbjct: 264  -PKSRYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--------- 310

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLI-------KPS 4666
                 + PP  +   +D++VA G+ + F C+  G P P + W + G + +       + S
Sbjct: 311  ----GSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSS 366

Query: 4667 KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ--PDQADNLPAL 4724
              F +S+T D   L I+     D G Y C   N AG +   A L+VT    D+   +   
Sbjct: 367  SRFSVSQTGD---LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ 423

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
             P+   V  +G         T    PTI W ++G L+  T D   I +  N VL I    
Sbjct: 424  GPVNQTVAVDG-TFVLSCVATGSPVPTILWRKDGVLV-STQD-SRIKQLENGVLQIRYAK 480

Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVVK 4811
              DTG +TC A+T +G+   SA + V+
Sbjct: 481  LGDTGRYTCIASTPSGEATWSAYIEVQ 507



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 81/309 (26%), Positives = 128/309 (41%), Gaps = 28/309 (9%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F K+     V   + A F+ E  G+P+P ++W +++  +  S  ++I    T   L I
Sbjct: 223  PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHT---LKI 278

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            R+V   D   +  VAEN  G A+ SA L V+        G  PP F +  ++  V  G+ 
Sbjct: 279  RKVTAGDMGSYTCVAENMVGKAEASATLTVQV-------GSEPPHFVVKPRDQVVALGRT 331

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKK-----VQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            V    + TG     ++W + G +      QP   +       T  L I      D G Y 
Sbjct: 332  VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C  +N AG     A   V+     D+P P  +          P+   +  +G  +  SC 
Sbjct: 392  CQTLNVAGSIITKAYLEVT-DVIADRPPPVIRQG--------PVNQTVAVDGTFV-LSCV 441

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P+PT+ W K   L+  S      +  +   L+I  A   D G Y C+A   +G  T
Sbjct: 442  ATGSPVPTILWRKDGVLV--STQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 499

Query: 4706 VAAKLKVTQ 4714
             +A ++V +
Sbjct: 500  WSAYIEVQE 508



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 79/316 (25%), Positives = 119/316 (37%), Gaps = 39/316 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+I + P +  + +G  A    +  G P P + W+K G+R+                  
Sbjct: 28  PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERV------------------ 69

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
              T K D   + +L  + +   +   +     P E         Y+ +         + 
Sbjct: 70  --ETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA 127

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVN 443
           I    L   F +   D  V  G+    +C+   G P P ++W   D    DD + +I + 
Sbjct: 128 I----LRDDFRQNPSDVMVVVGEPAVMECQPPRGHPEPTISWK-KDGSPLDDKDERITIR 182

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ-CRLNVIEKEQVVAPKFVERFSTLNV 502
                 LMIT    SD+G   CV  N  GE   +   L V+E+     P FV+R S L V
Sbjct: 183 GG---KLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLER-----PSFVKRPSNLAV 234

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              +       A G P P + W+KD    +P     I  D    TL I +  A D   Y 
Sbjct: 235 TVDDSAEFKCEARGDPVPTVRWRKDDGE-LPKSRYEIRDD---HTLKIRKVTAGDMGSYT 290

Query: 563 CTAQNVAGSTATRARL 578
           C A+N+ G     A L
Sbjct: 291 CVAENMVGKAEASATL 306



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 58/193 (30%), Positives = 89/193 (46%), Gaps = 13/193 (6%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR----DDYNHKI 440
           + ++   P+ V+   D  V++G+    +C+  GRP P + W+    ++     D  +H++
Sbjct: 22  LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81

Query: 441 LVNESGNHALMITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498
           L+       L I +   S  D GV  CVARN  GE       N   +  ++   F +  S
Sbjct: 82  LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH---NASLEVAILRDDFRQNPS 138

Query: 499 TLNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            + V  GEP V+  +   G P P I+W+KDG P+    E RI   GG   L I   + SD
Sbjct: 139 DVMVVVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDE-RITIRGG--KLMITYTRKSD 195

Query: 558 AAWYQCTAQNVAG 570
           A  Y C   N+ G
Sbjct: 196 AGKYVCVGTNMVG 208



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 61/206 (29%), Positives = 82/206 (39%), Gaps = 14/206 (6%)

Query: 380 EERIEISEKALA--PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
           E   E++E  +   P FVK   +  VT      F C   G P P V W  +D ++     
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-R 267

Query: 438 HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
           ++I      +H L I  VT  D G  TCVA N  G+      L V    +   P FV + 
Sbjct: 268 YEI----RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSE--PPHFVVKP 321

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPII-----PNPELRIHTDGGASTLDIPR 552
               V  G  V     A G P P I W+++G   +     P       +      L I  
Sbjct: 322 RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITN 381

Query: 553 AKASDAAWYQCTAQNVAGSTATRARL 578
            + SD  +Y C   NVAGS  T+A L
Sbjct: 382 VQRSDVGYYICQTLNVAGSIITKAYL 407



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 67/293 (22%), Positives = 117/293 (39%), Gaps = 16/293 (5%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F +   N       +A+F+ + RG+P P V W +    L + ++Y +R      D +L
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEIR-----DDHTL 276

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE-GXXXXXXXXXXXXXYRHVSETVEHKA 190
            I+++  GD G YTC A N  G+A  S  +  + G                +  TV  + 
Sbjct: 277 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQC 336

Query: 191 YGT---QGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLR----EVSFRESITKR 243
             T   Q     +   +Q + ++     SS+      T +  +      +V +    T  
Sbjct: 337 EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLN 396

Query: 244 YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             G    +   E+   +    PP I Q P N  +            +G+P P + W K+G
Sbjct: 397 VAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDG 456

Query: 304 QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
             ++ S +   I    +  L++R  +  D+G YT +A  P+G    S Y+ V+
Sbjct: 457 --VLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 62/196 (31%), Positives = 86/196 (43%), Gaps = 19/196 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-IRDDY-----NHKILVNES 445
           P FV   +D+ V  G+   F C  TG P P + W     Q +   Y     + +  V+++
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 374

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLN-- 501
           G+  L ITNV  SD G   C   N +G    +  L V +   V+A  P  V R   +N  
Sbjct: 375 GD--LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD---VIADRPPPVIRQGPVNQT 429

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-HTDGGASTLDIPRAKASDAAW 560
           V      VL+  A G+P P I W+KDGV ++   + RI   + G   L I  AK  D   
Sbjct: 430 VAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENG--VLQIRYAKLGDTGR 486

Query: 561 YQCTAQNVAGSTATRA 576
           Y C A   +G     A
Sbjct: 487 YTCIASTPSGEATWSA 502



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 99/435 (22%), Positives = 158/435 (36%), Gaps = 49/435 (11%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P +SW +  +PL + ++   R   + G   L+I      D G+Y C   N  GE 
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDE---RITIRGG--KLMITYTRKSDAGKYVCVGTNMVGER 210

Query: 156 ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDH 215
              V  +                   V ++ E K    +G      R  +       + +
Sbjct: 211 ESEV-AELTVLERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRY 268

Query: 216 SSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNS 275
              DD  +   +     ++     + +  VG+++   +  +   +G   PP    KPR+ 
Sbjct: 269 EIRDDHTLKIRKVTA-GDMGSYTCVAENMVGKAEASATLTVQ--VGS-EPPHFVVKPRDQ 324

Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNG-QRLINS----NKHEIITTHNHTTLRVRNTQK 330
            +  G    FQ + +GNP+P + W + G Q L+ S          +      L + N Q+
Sbjct: 325 VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQR 384

Query: 331 SDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKAL 390
           SD G+Y     N  G I+T  YL V       + D+    I      +T         A+
Sbjct: 385 SDVGYYICQTLNVAGSIITKAYLEV----TDVIADRPPPVIRQGPVNQT--------VAV 432

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
              FV  C    V  G            P P + W   D  +    + +I   E+G   L
Sbjct: 433 DGTFVLSC----VATGS-----------PVPTILW-RKDGVLVSTQDSRIKQLENG--VL 474

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I    L D+G  TC+A   SGE  +   + V E    V P    R +  N+    P   
Sbjct: 475 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQP---PRPTDPNLIPSAPSKP 531

Query: 511 NARAVGTPTPRITWQ 525
               V   T  ++WQ
Sbjct: 532 EVTDVSRNTVTLSWQ 546



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 75/312 (24%), Positives = 114/312 (36%), Gaps = 18/312 (5%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT- 126
           E  PP   +   +   ++G  A    K  G PTP + W  K    VE +K   R +    
Sbjct: 25  EDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWY-KGGERVETDKDDPRSHRMLL 83

Query: 127 GDVSLLIKQIGPG-----DEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRH 181
              SL   +I  G     DEG Y C ARN  GEA+                         
Sbjct: 84  PSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVV 143

Query: 182 VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
           V E    +    +G+        +  +  +  D   T         Y    +      + 
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVG 203

Query: 242 KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
              VGE + +++      L  +  P   ++P N  +     A+F+ +  G+P P V W K
Sbjct: 204 TNMVGERESEVA-----ELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRK 258

Query: 302 NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE- 360
           +   L  S ++EI   H   TL++R     D G YT +AEN  G    S  L V+  +E 
Sbjct: 259 DDGELPKS-RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314

Query: 361 -SYVQDQRSQYI 371
             +V   R Q +
Sbjct: 315 PHFVVKPRDQVV 326



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 92/354 (25%), Positives = 136/354 (38%), Gaps = 93/354 (26%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL---TVYGE 1912
            +S+G+ A   C+ E  P P   +EWY  G+ +++      S+     +  +     V+G 
Sbjct: 40   VSKGEPATLNCKAEGRPTPT--IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97

Query: 1913 ----DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAV 1968
                D G Y C A N LG+AVS                 H ++LE +  L DD  +++  
Sbjct: 98   KSRPDEGVYVCVARNYLGEAVS-----------------HNASLE-VAILRDD--FRQNP 137

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
             D   VV +P     +   +   GHP           +PT  + W  +G P+      + 
Sbjct: 138  SDVMVVVGEP----AVMECQPPRGHP-----------EPT--ISWKKDGSPLDDKDE-RI 179

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKI 2088
            T   G   L I Y    D G Y+C  TN VGE                       R  ++
Sbjct: 180  TIRGG--KLMITYTRKSDAGKYVCVGTNMVGE-----------------------RESEV 214

Query: 2089 QELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW-FH 2147
             EL   ERP  +      +RP  L            D A F+C  E   DP  T+ W   
Sbjct: 215  AELTVLERPSFV------KRPSNLAVTVD-------DSAEFKC--EARGDPVPTVRWRKD 259

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +G+  ++ +  R  H      L I    A D G+Y C A N +G+A  + TL V
Sbjct: 260  DGELPKSRYEIRDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 64/242 (26%), Positives = 85/242 (35%), Gaps = 18/242 (7%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE---NFPIKNSPDFQIHTFST 4464
            S+PP F  K +   V       F+ E  G P P I W RE   N      P      FS 
Sbjct: 312  SEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV 371

Query: 4465 KSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
                 L I  V   D   +     N  G+    A L V +          PP       N
Sbjct: 372  SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR----PPPVIRQGPVN 427

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEAYPQDS 4581
              V       L    TG+    + W K+G  V   D R K LE      L I  A   D+
Sbjct: 428  QTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG---VLQIRYAKLGDT 484

Query: 4582 GKYECVAINSAGEARCDAECVV---SLPATKDKPKPQTKAANAP--PEIIEPLKDKIVAE 4636
            G+Y C+A   +GEA   A   V    +P    +P       +AP  PE+ +  ++ +   
Sbjct: 485  GRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLS 544

Query: 4637 GQ 4638
             Q
Sbjct: 545  WQ 546



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 7/97 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-----IPNPELRI 539
           +++   P+ VE  S L V +GEP  LN +A G PTP I W K G  +      P     +
Sbjct: 23  RQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRML 82

Query: 540 HTDGGASTLDIPRAKAS--DAAWYQCTAQNVAGSTAT 574
              G    L I   + S  D   Y C A+N  G   +
Sbjct: 83  LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 119



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 50/196 (25%), Positives = 78/196 (39%), Gaps = 24/196 (12%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA------SHRIRTV 3100
            PP       D++ +S+G+ A         G  +  IEW+  G+ +E       SHR+   
Sbjct: 28   PPRIVEHPSDLI-VSKGEPATLNCKA--EGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84

Query: 3101 YAFGMVVLEILGTKTT-DSGTYSCRATNKWGQA---EISVKLECVDKSKGQKPRFTTHIQ 3156
                  +  + G K+  D G Y C A N  G+A     S+++  +     Q P     + 
Sbjct: 85   SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVVV 144

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
                   G+ A  EC   P   P+  I W  +G P+       T+     +   I YT+ 
Sbjct: 145  -------GEPAVMECQP-PRGHPEPTISWKKDGSPLDDKDERITIRGGKLM---ITYTRK 193

Query: 3217 HDSGEYVCRAYNKYGE 3232
             D+G+YVC   N  GE
Sbjct: 194  SDAGKYVCVGTNMVGE 209



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 60/238 (25%), Positives = 93/238 (39%), Gaps = 48/238 (20%)

Query: 1700 HSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            H+A  EV      F     D+ V   + A  E +  P G P+  + W ++G P++  +  
Sbjct: 120  HNASLEVAILRDDFRQNPSDVMVVVGEPAVMECQP-PRGHPEPTISWKKDGSPLDDKDER 178

Query: 1760 TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
             T+       L + Y    D+G Y C   N +GE                     ES + 
Sbjct: 179  ITIRGG---KLMITYTRKSDAGKYVCVGTNMVGE--------------------RESEVA 215

Query: 1820 KIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879
            ++  LE  S  +R  ++ V V+ +  F                  E R +P P    R +
Sbjct: 216  ELTVLERPSFVKRPSNLAVTVDDSAEF----------------KCEARGDPVPTVRWRKD 259

Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               +G++ +S  RY   +D     L I  V   D G YTC A N +G+A +S  L VQ
Sbjct: 260  ---DGELPKS--RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/92 (32%), Positives = 38/92 (41%), Gaps = 4/92 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+  Q   N   A  G         G+P P + W RK   LV      ++   Q  +  
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILW-RKDGVLVSTQDSRIK---QLENGV 473

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L I+    GD G YTC A    GEA  S YI+
Sbjct: 474 LQIRYAKLGDTGRYTCIASTPSGEATWSAYIE 505



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 16/138 (11%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L+I      D G+Y+C A N  G+AE S  L    +   + P F    ++ + +  G++ 
Sbjct: 276  LKIRKVTAGDMGSYTCVAENMVGKAEASATLTV--QVGSEPPHFVVKPRD-QVVALGRTV 332

Query: 3168 HFECTVVPVDDPDMKIEWYHNG--------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
             F+C      +P   I W   G        QP + S+R  +VS  G   L I   Q  D 
Sbjct: 333  TFQCEA--TGNPQPAIFWRREGSQNLLFSYQPPQSSSRF-SVSQTG--DLTITNVQRSDV 387

Query: 3220 GEYVCRAYNKYGEDFTRA 3237
            G Y+C+  N  G   T+A
Sbjct: 388  GYYICQTLNVAGSIITKA 405



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 9/106 (8%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN-GQPVTI 1489
            +++++ + +V  +P FV RP ++   ++     F+C  E   D    V W K+ G+    
Sbjct: 210  RESEVAELTVLERPSFVKRPSNLAVTVDDS-AEFKC--EARGDPVPTVRWRKDDGELPKS 266

Query: 1490 GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             +  R  H      L I  + A D G YTC A N+VG  E S  LT
Sbjct: 267  RYEIRDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLT 307



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 7/104 (6%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ + ++P F+         V+  SA F+   E + D   TV W  +  ++  + R +  
Sbjct: 216  ELTVLERPSFVKRPSNLAVTVD-DSAEFKC--EARGDPVPTVRWRKDDGELPKS-RYEIR 271

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139
             D     L I  V A D G YT VA N  G+A+ SA++TV+  S
Sbjct: 272  DDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGS 312



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 9/96 (9%)

Query: 907  QKPEF-KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            ++P F K P    +++ +      EAR    GD    V W KD   +   SR     +  
Sbjct: 221  ERPSFVKRPSNLAVTVDDSAEFKCEAR----GDPVPTVRWRKDDGELP-KSRYEIRDDH- 274

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
               L I+ VT  D G YTC A N +G+A  SA LT+
Sbjct: 275  --TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 14/166 (8%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            P G     I W  +G  ++      T+    +++     T+ +D+G Y C  TN  G+ E
Sbjct: 155  PRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITY---TRKSDAGKYVCVGTNMVGERE 211

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
                 E  + +  ++P F     N+    D  SA F+C      DP   + W  +   + 
Sbjct: 212  ----SEVAELTVLERPSFVKRPSNLAVTVD-DSAEFKCEA--RGDPVPTVRWRKDDGELP 264

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
             S R +   D     L I      D G Y C A N  G+    AT+
Sbjct: 265  KS-RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATL 306



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 1698 QRHSAQDEV-ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
            +R S   E+ + + P F     ++ V  + +A F+      GDP   V W ++   +  S
Sbjct: 209  ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGELPKS 266

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
             R     D     L ++ V   D G+YTC A N +G+A  S+TL VQ
Sbjct: 267  -RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+   +N+     D+  F+C  E   DP   + W  ++  LP  +RY+   D +   L I
Sbjct: 225  FVKRPSNLAVTVDDSAEFKC--EARGDPVPTVRWRKDDGELPK-SRYEIRDDHT---LKI 278

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                  D G YTC A N  G A  S +L
Sbjct: 279  RKVTAGDMGSYTCVAENMVGKAEASATL 306



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 9/79 (11%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-----MTISHVR 2442
            + +G+ A  +C+    G PT  +EW++  + +E      ++H     S     + I H R
Sbjct: 40   VSKGEPATLNCKA--EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97

Query: 2443 DE--DEGVYMCRASNLLGE 2459
                DEGVY+C A N LGE
Sbjct: 98   KSRPDEGVYVCVARNYLGE 116



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 13/102 (12%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASSRFTS 687
           PP F+V  +      G  + F+   E  G+P   I W + G        Q  ++SSRF S
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF-S 370

Query: 688 IFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           + + G   L + ++   D G Y C+ ++  G   TKA L VT
Sbjct: 371 VSQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT 410



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 9/107 (8%)

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN-GKPIKT 1355
            R  +V E +TV++ P F +   N+      +   +C  +  GD    V W  + G+  K+
Sbjct: 210  RESEVAE-LTVLERPSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGELPKS 266

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +  R     D   L +  V   D G YTC A N +G+A  S  L V
Sbjct: 267  RYEIR-----DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 7/97 (7%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLV----ECNKYSMRYN-EQ 125
           PP F    ++   A G    F+ +  GNP P + W R+ +  +    +  + S R++  Q
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 373

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           TGD  L I  +   D G Y C   N  G  I   Y++
Sbjct: 374 TGD--LTITNVQRSDVGYYICQTLNVAGSIITKAYLE 408



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 6/93 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   PS+L ++ + SA F+C      D    V W  +   L   SR +  +D     L
Sbjct: 223  PSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGEL-PKSRYEIRDDH---TL 276

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            +I  V   D G YTC A N  G+A  S  L V+
Sbjct: 277  KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/115 (30%), Positives = 48/115 (41%), Gaps = 14/115 (12%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK--LL-----PSGHRYR 3879
            S PP F+ + +   V     V F+C  E   +P+  I W R G   LL     P      
Sbjct: 312  SEPPHFVVKPRDQVVALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 369

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVP 3934
            +V   G   L I  V   D G YIC+ +N  G   TKA +   ++ D+I     P
Sbjct: 370  SVSQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYL---EVTDVIADRPPP 419



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLR------- 2708
            +G+   L  + E R  P   IEW+K G  + T      +    L + S+  LR       
Sbjct: 42   KGEPATLNCKAEGRPTPT--IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99

Query: 2709 NDDSGIYTCKATNLLGEAVS-TASIKI 2734
              D G+Y C A N LGEAVS  AS+++
Sbjct: 100  RPDEGVYVCVARNYLGEAVSHNASLEV 126



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 5/96 (5%)

Query: 3978 QIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGW 4037
            Q  S   +V  E    ECQ  P G P   + W  +G PL  K+    I   G + + +  
Sbjct: 135  QNPSDVMVVVGEPAVMECQ-PPRGHPEPTISWKKDGSPLDDKDERITIRG-GKLMITY-- 190

Query: 4038 VYPEDSGEYLCRATNLYGMDETK-AVIKTTGKPGIV 4072
                D+G+Y+C  TN+ G  E++ A +    +P  V
Sbjct: 191  TRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFV 226



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 4/73 (5%)

Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNL 2722
            E + E R DP   + W K+   L   +R +   D    TL I  +   D G YTC A N+
Sbjct: 241  EFKCEARGDPVPTVRWRKDDGELPK-SRYEIRDDH---TLKIRKVTAGDMGSYTCVAENM 296

Query: 2723 LGEAVSTASIKIE 2735
            +G+A ++A++ ++
Sbjct: 297  VGKAEASATLTVQ 309



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            +V G+   +E Q  PR  P   I W K+G  L      + T   G   L I   R  D+G
Sbjct: 142  VVVGEPAVMECQ-PPRGHPEPTISWKKDGSPLDDKDE-RITIRGG--KLMITYTRKSDAG 197

Query: 2714 IYTCKATNLLGEAVS-TASIKIEDR 2737
             Y C  TN++GE  S  A + + +R
Sbjct: 198  KYVCVGTNMVGERESEVAELTVLER 222



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 6/91 (6%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F+ +  +  V   +   F+C  E + DP   + W ++   LP   RY    D    +L
Sbjct: 223  PSFVKRPSNLAVTVDDSAEFKC--EARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TL 276

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
             I  V A D G Y C A N  G+    AT++
Sbjct: 277  KIRKVTAGDMGSYTCVAENMVGKAEASATLT 307



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 2/74 (2%)

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
            F    +  G P   + W ++GV +   +      + G   L ++Y    D+G YTC A  
Sbjct: 436  FVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIAST 493

Query: 1790 ELGEAVTSSTLFVQ 1803
              GEA  S+ + VQ
Sbjct: 494  PSGEATWSAYIEVQ 507



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 11/107 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTL--- 3747
            PPR  VE   ++ V +G P   +C+ E  G PT  I+W+  G    T     R H +   
Sbjct: 28   PPRI-VEHPSDLIVSKGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84

Query: 3748 -NDFGFIALDIDYIYARDAGEYTCRATNKWGSATT-TAKITCSAKRD 3792
                 F+ +        D G Y C A N  G A +  A +  +  RD
Sbjct: 85   SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRD 131



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT------GSRVKTIN 3610
            PP     PSDLI+S+   A   C+       +  +EW+  G+ + T        R+   +
Sbjct: 28   PPRIVEHPSDLIVSKGEPATLNCK--AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85

Query: 3611 DFGFVILEIGGVYQR-DAGLYTCKATNRHGEA 3641
               F +  + G   R D G+Y C A N  GEA
Sbjct: 86   GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEA 117



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-----GYVALDILYTY 2175
            + +G+ A   C+ E    P  TI+W+  G+++        +H           L I++  
Sbjct: 40   VSKGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97

Query: 2176 AE--DSGTYMCKATNKLGEAV-NTCTLKVA 2202
                D G Y+C A N LGEAV +  +L+VA
Sbjct: 98   KSRPDEGVYVCVARNYLGEAVSHNASLEVA 127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 10/92 (10%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT------GHRFR-PAYEFDYVALDLLSVY 1376
            +G    L C+ +  G  T  +EW+  G+ ++T       HR   P+    ++ +      
Sbjct: 42   KGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99

Query: 1377 PEDSGVYTCQATNQLGEAVT-SCALRVIAKKD 1407
              D GVY C A N LGEAV+ + +L V   +D
Sbjct: 100  RPDEGVYVCVARNYLGEAVSHNASLEVAILRD 131



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 7/110 (6%)

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
           +  E  E    +RP F++   +L    +  +A F+ +     DP   V W KD   +  S
Sbjct: 210 RESEVAELTVLERPSFVKRPSNLAVTVDD-SAEFKCEAR--GDPVPTVRWRKDDGELPKS 266

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
                  +    +L I  + A D GSYT  A N +G+A ++A++ V   S
Sbjct: 267 RYEIRDDH----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGS 312



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 17/121 (14%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG--------RPVE 953
            V   ++ P F    +DQ+ +  G    F+   E  G+    + W ++G        +P +
Sbjct: 308  VQVGSEPPHFVVKPRDQV-VALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQ 364

Query: 954  ASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            +SSR +         LTI +V   D G+Y C+  N  G   T A L +    D+IA+   
Sbjct: 365  SSSRFSVSQTGD---LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT---DVIADRPP 418

Query: 1014 P 1014
            P
Sbjct: 419  P 419



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/40 (37%), Positives = 19/40 (47%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            PP FV  P    V  G    F C  TG+P+P + W   G+
Sbjct: 314  PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS 353


>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
          Length = 1606

 Score =  104 bits (249), Expect = 9e-21
 Identities = 109/414 (26%), Positives = 162/414 (39%), Gaps = 45/414 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI---KNSPDFQIHTFSTKS 4466
            PP   +      V + E A    + +G P P I+WY+    +   K+ P        + S
Sbjct: 28   PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 87

Query: 4467 ILIIRQVFVE----DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            +  +R V       D  V+  VA N  G A  S N  +E         I+   F     +
Sbjct: 88   LFFLRIVHGRKSRPDEGVYVCVARNYLGEA-VSHNASLEV-------AILRDDFRQNPSD 139

Query: 4523 VNVTSGQLVRLDTK-VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            V V  G+   ++ +   G     + W K+G  +  D   +I    G   L+I      D+
Sbjct: 140  VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG--KLMITYTRKSDA 196

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            GKY CV  N  GE   +   V  L   +             P  ++   +  V    + E
Sbjct: 197  GKYVCVGTNMVGERESE---VAELTVLE------------RPSFVKRPSNLAVTVDDSAE 241

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            F C+  G P+PTV+W K D  +  S+Y       D++TL+I +    D G Y CVA N  
Sbjct: 242  FKCEARGDPVPTVRWRKDDGELPKSRY----EIRDDHTLKIRKVTAGDMGSYTCVAENMV 297

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-- 4759
            G+   +A L V    +  +   + P RD VV  G+   F+ + T   +P I W REG+  
Sbjct: 298  GKAEASATLTVQVGSEPPHF-VVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQN 355

Query: 4760 -LIPETP--DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L    P              L I N    D G + C+    AG + T A L V
Sbjct: 356  LLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 409



 Score =  103 bits (246), Expect = 2e-20
 Identities = 106/387 (27%), Positives = 160/387 (41%), Gaps = 47/387 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++  P+ +  D +I     K  L+I      D+  +  V  N  G  +  
Sbjct: 157  GHPEPTISWKKDGSPLDDK-DERITIRGGK--LMITYTRKSDAGKYVCVGTNMVGERESE 213

Query: 4496 -ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
             A L V E+          PSF     N+ VT         +  G     V W K+  ++
Sbjct: 214  VAELTVLER----------PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL 263

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R +I ++   +TL I +    D G Y CVA N  G+A   A   V +         
Sbjct: 264  -PKSRYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--------- 310

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLI-------KPS 4666
                 + PP  +   +D++VA G+ + F C+  G P P + W + G + +       + S
Sbjct: 311  ----GSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSS 366

Query: 4667 KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ--PDQADNLPAL 4724
              F +S+T D   L I+     D G Y C   N AG +   A L+VT    D+   +   
Sbjct: 367  SRFSVSQTGD---LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ 423

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
             P+   V  +G         T    PTI W ++G L+  T D   I +  N VL I    
Sbjct: 424  GPVNQTVAVDG-TFVLSCVATGSPVPTILWRKDGVLV-STQD-SRIKQLENGVLQIRYAK 480

Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVVK 4811
              DTG +TC A+T +G+   SA + V+
Sbjct: 481  LGDTGRYTCIASTPSGEATWSAYIEVQ 507



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 81/309 (26%), Positives = 128/309 (41%), Gaps = 28/309 (9%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F K+     V   + A F+ E  G+P+P ++W +++  +  S  ++I    T   L I
Sbjct: 223  PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHT---LKI 278

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            R+V   D   +  VAEN  G A+ SA L V+        G  PP F +  ++  V  G+ 
Sbjct: 279  RKVTAGDMGSYTCVAENMVGKAEASATLTVQV-------GSEPPHFVVKPRDQVVALGRT 331

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKK-----VQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            V    + TG     ++W + G +      QP   +       T  L I      D G Y 
Sbjct: 332  VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C  +N AG     A   V+     D+P P  +          P+   +  +G  +  SC 
Sbjct: 392  CQTLNVAGSIITKAYLEVT-DVIADRPPPVIRQG--------PVNQTVAVDGTFV-LSCV 441

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P+PT+ W K   L+  S      +  +   L+I  A   D G Y C+A   +G  T
Sbjct: 442  ATGSPVPTILWRKDGVLV--STQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 499

Query: 4706 VAAKLKVTQ 4714
             +A ++V +
Sbjct: 500  WSAYIEVQE 508



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 79/316 (25%), Positives = 119/316 (37%), Gaps = 39/316 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+I + P +  + +G  A    +  G P P + W+K G+R+                  
Sbjct: 28  PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERV------------------ 69

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
              T K D   + +L  + +   +   +     P E         Y+ +         + 
Sbjct: 70  --ETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA 127

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVN 443
           I    L   F +   D  V  G+    +C+   G P P ++W   D    DD + +I + 
Sbjct: 128 I----LRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWK-KDGSPLDDKDERITIR 182

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ-CRLNVIEKEQVVAPKFVERFSTLNV 502
                 LMIT    SD+G   CV  N  GE   +   L V+E+     P FV+R S L V
Sbjct: 183 GG---KLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLER-----PSFVKRPSNLAV 234

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              +       A G P P + W+KD    +P     I  D    TL I +  A D   Y 
Sbjct: 235 TVDDSAEFKCEARGDPVPTVRWRKDDGE-LPKSRYEIRDD---HTLKIRKVTAGDMGSYT 290

Query: 563 CTAQNVAGSTATRARL 578
           C A+N+ G     A L
Sbjct: 291 CVAENMVGKAEASATL 306



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 58/193 (30%), Positives = 89/193 (46%), Gaps = 13/193 (6%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR----DDYNHKI 440
           + ++   P+ V+   D  V++G+    +C+  GRP P + W+    ++     D  +H++
Sbjct: 22  LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81

Query: 441 LVNESGNHALMITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498
           L+       L I +   S  D GV  CVARN  GE       N   +  ++   F +  S
Sbjct: 82  LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH---NASLEVAILRDDFRQNPS 138

Query: 499 TLNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            + V  GEP V+  +   G P P I+W+KDG P+    E RI   GG   L I   + SD
Sbjct: 139 DVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDE-RITIRGG--KLMITYTRKSD 195

Query: 558 AAWYQCTAQNVAG 570
           A  Y C   N+ G
Sbjct: 196 AGKYVCVGTNMVG 208



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 61/206 (29%), Positives = 82/206 (39%), Gaps = 14/206 (6%)

Query: 380 EERIEISEKALA--PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
           E   E++E  +   P FVK   +  VT      F C   G P P V W  +D ++     
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-R 267

Query: 438 HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
           ++I      +H L I  VT  D G  TCVA N  G+      L V    +   P FV + 
Sbjct: 268 YEI----RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSE--PPHFVVKP 321

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPII-----PNPELRIHTDGGASTLDIPR 552
               V  G  V     A G P P I W+++G   +     P       +      L I  
Sbjct: 322 RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITN 381

Query: 553 AKASDAAWYQCTAQNVAGSTATRARL 578
            + SD  +Y C   NVAGS  T+A L
Sbjct: 382 VQRSDVGYYICQTLNVAGSIITKAYL 407



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 67/293 (22%), Positives = 117/293 (39%), Gaps = 16/293 (5%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F +   N       +A+F+ + RG+P P V W +    L + ++Y +R      D +L
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEIR-----DDHTL 276

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE-GXXXXXXXXXXXXXYRHVSETVEHKA 190
            I+++  GD G YTC A N  G+A  S  +  + G                +  TV  + 
Sbjct: 277 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQC 336

Query: 191 YGT---QGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLR----EVSFRESITKR 243
             T   Q     +   +Q + ++     SS+      T +  +      +V +    T  
Sbjct: 337 EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLN 396

Query: 244 YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             G    +   E+   +    PP I Q P N  +            +G+P P + W K+G
Sbjct: 397 VAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDG 456

Query: 304 QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
             ++ S +   I    +  L++R  +  D+G YT +A  P+G    S Y+ V+
Sbjct: 457 --VLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 62/196 (31%), Positives = 86/196 (43%), Gaps = 19/196 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-IRDDY-----NHKILVNES 445
           P FV   +D+ V  G+   F C  TG P P + W     Q +   Y     + +  V+++
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 374

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLN-- 501
           G+  L ITNV  SD G   C   N +G    +  L V +   V+A  P  V R   +N  
Sbjct: 375 GD--LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD---VIADRPPPVIRQGPVNQT 429

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-HTDGGASTLDIPRAKASDAAW 560
           V      VL+  A G+P P I W+KDGV ++   + RI   + G   L I  AK  D   
Sbjct: 430 VAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENG--VLQIRYAKLGDTGR 486

Query: 561 YQCTAQNVAGSTATRA 576
           Y C A   +G     A
Sbjct: 487 YTCIASTPSGEATWSA 502



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 77/308 (25%), Positives = 119/308 (38%), Gaps = 35/308 (11%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-----PDIRNKILEEDG 4567
            PP       ++ V+ G+   L+ K  G     + W K G++V+     P     +L    
Sbjct: 28   PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 87

Query: 4568 TYTLLILEAYPQ--DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             + L I+       D G Y CVA N  GEA       VS  A+        + A    + 
Sbjct: 88   LFFLRIVHGRKSRPDEGVYVCVARNYLGEA-------VSHNAS-------LEVAILRDDF 133

Query: 4626 IEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
             +   D +VA G+     C+   G P PT+ W K      P        T     L I+ 
Sbjct: 134  RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDG---SPLDDKDERITIRGGKLMITY 190

Query: 4685 AFPEDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                D G Y CV  N  G R +  A+L V +       P+     ++ V     A+FK +
Sbjct: 191  TRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPS-----NLAVTVDDSAEFKCE 245

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                  PT++W ++   +P++         ++  L I      D G++TC A    G+ E
Sbjct: 246  ARGDPVPTVRWRKDDGELPKS----RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAE 301

Query: 4804 TSAKLVVK 4811
             SA L V+
Sbjct: 302  ASATLTVQ 309



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 99/435 (22%), Positives = 158/435 (36%), Gaps = 49/435 (11%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P +SW +  +PL + ++   R   + G   L+I      D G+Y C   N  GE 
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDE---RITIRGG--KLMITYTRKSDAGKYVCVGTNMVGER 210

Query: 156 ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDH 215
              V  +                   V ++ E K    +G      R  +       + +
Sbjct: 211 ESEV-AELTVLERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRY 268

Query: 216 SSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNS 275
              DD  +   +     ++     + +  VG+++   +  +   +G   PP    KPR+ 
Sbjct: 269 EIRDDHTLKIRKVTA-GDMGSYTCVAENMVGKAEASATLTVQ--VGS-EPPHFVVKPRDQ 324

Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNG-QRLINS----NKHEIITTHNHTTLRVRNTQK 330
            +  G    FQ + +GNP+P + W + G Q L+ S          +      L + N Q+
Sbjct: 325 VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQR 384

Query: 331 SDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKAL 390
           SD G+Y     N  G I+T  YL V       + D+    I      +T         A+
Sbjct: 385 SDVGYYICQTLNVAGSIITKAYLEV----TDVIADRPPPVIRQGPVNQT--------VAV 432

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
              FV  C    V  G            P P + W   D  +    + +I   E+G   L
Sbjct: 433 DGTFVLSC----VATGS-----------PVPTILW-RKDGVLVSTQDSRIKQLENG--VL 474

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I    L D+G  TC+A   SGE  +   + V E    V P    R +  N+    P   
Sbjct: 475 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQP---PRPTDPNLIPSAPSKP 531

Query: 511 NARAVGTPTPRITWQ 525
               V   T  ++WQ
Sbjct: 532 EVTDVSRNTVTLSWQ 546



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 75/312 (24%), Positives = 114/312 (36%), Gaps = 18/312 (5%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT- 126
           E  PP   +   +   ++G  A    K  G PTP + W  K    VE +K   R +    
Sbjct: 25  EDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWY-KGGERVETDKDDPRSHRMLL 83

Query: 127 GDVSLLIKQIGPG-----DEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRH 181
              SL   +I  G     DEG Y C ARN  GEA+                         
Sbjct: 84  PSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVA 143

Query: 182 VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
           V E    +    +G+        +  +  +  D   T         Y    +      + 
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVG 203

Query: 242 KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
              VGE + +++      L  +  P   ++P N  +     A+F+ +  G+P P V W K
Sbjct: 204 TNMVGERESEVA-----ELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRK 258

Query: 302 NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE- 360
           +   L  S ++EI   H   TL++R     D G YT +AEN  G    S  L V+  +E 
Sbjct: 259 DDGELPKS-RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314

Query: 361 -SYVQDQRSQYI 371
             +V   R Q +
Sbjct: 315 PHFVVKPRDQVV 326



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 64/242 (26%), Positives = 85/242 (35%), Gaps = 18/242 (7%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE---NFPIKNSPDFQIHTFST 4464
            S+PP F  K +   V       F+ E  G P P I W RE   N      P      FS 
Sbjct: 312  SEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV 371

Query: 4465 KSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
                 L I  V   D   +     N  G+    A L V +          PP       N
Sbjct: 372  SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR----PPPVIRQGPVN 427

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEAYPQDS 4581
              V       L    TG+    + W K+G  V   D R K LE      L I  A   D+
Sbjct: 428  QTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG---VLQIRYAKLGDT 484

Query: 4582 GKYECVAINSAGEARCDAECVV---SLPATKDKPKPQTKAANAP--PEIIEPLKDKIVAE 4636
            G+Y C+A   +GEA   A   V    +P    +P       +AP  PE+ +  ++ +   
Sbjct: 485  GRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLS 544

Query: 4637 GQ 4638
             Q
Sbjct: 545  WQ 546



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 7/97 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-----IPNPELRI 539
           +++   P+ VE  S L V +GEP  LN +A G PTP I W K G  +      P     +
Sbjct: 23  RQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRML 82

Query: 540 HTDGGASTLDIPRAKAS--DAAWYQCTAQNVAGSTAT 574
              G    L I   + S  D   Y C A+N  G   +
Sbjct: 83  LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 119



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 91/354 (25%), Positives = 135/354 (38%), Gaps = 93/354 (26%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL---TVYGE 1912
            +S+G+ A   C+ E  P P   +EWY  G+ +++      S+     +  +     V+G 
Sbjct: 40   VSKGEPATLNCKAEGRPTPT--IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97

Query: 1913 ----DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAV 1968
                D G Y C A N LG+AVS                 H ++LE +  L DD  +++  
Sbjct: 98   KSRPDEGVYVCVARNYLGEAVS-----------------HNASLE-VAILRDD--FRQNP 137

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
             D    V +P     +   +   GHP           +PT  + W  +G P+      + 
Sbjct: 138  SDVMVAVGEP----AVMECQPPRGHP-----------EPT--ISWKKDGSPLDDKDE-RI 179

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKI 2088
            T   G   L I Y    D G Y+C  TN VGE                       R  ++
Sbjct: 180  TIRGG--KLMITYTRKSDAGKYVCVGTNMVGE-----------------------RESEV 214

Query: 2089 QELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW-FH 2147
             EL   ERP  +      +RP  L            D A F+C  E   DP  T+ W   
Sbjct: 215  AELTVLERPSFV------KRPSNLAVTVD-------DSAEFKC--EARGDPVPTVRWRKD 259

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +G+  ++ +  R  H      L I    A D G+Y C A N +G+A  + TL V
Sbjct: 260  DGELPKSRYEIRDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 50/196 (25%), Positives = 78/196 (39%), Gaps = 24/196 (12%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA------SHRIRTV 3100
            PP       D++ +S+G+ A         G  +  IEW+  G+ +E       SHR+   
Sbjct: 28   PPRIVEHPSDLI-VSKGEPATLNCKA--EGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84

Query: 3101 YAFGMVVLEILGTKTT-DSGTYSCRATNKWGQA---EISVKLECVDKSKGQKPRFTTHIQ 3156
                  +  + G K+  D G Y C A N  G+A     S+++  +     Q P       
Sbjct: 85   SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVM--- 141

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
                +  G+ A  EC   P   P+  I W  +G P+       T+     +   I YT+ 
Sbjct: 142  ----VAVGEPAVMECQP-PRGHPEPTISWKKDGSPLDDKDERITIRGGKLM---ITYTRK 193

Query: 3217 HDSGEYVCRAYNKYGE 3232
             D+G+YVC   N  GE
Sbjct: 194  SDAGKYVCVGTNMVGE 209



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 61/238 (25%), Positives = 94/238 (39%), Gaps = 48/238 (20%)

Query: 1700 HSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            H+A  EV      F     D+ VA  + A  E +  P G P+  + W ++G P++  +  
Sbjct: 120  HNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQP-PRGHPEPTISWKKDGSPLDDKDER 178

Query: 1760 TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
             T+       L + Y    D+G Y C   N +GE                     ES + 
Sbjct: 179  ITIRGG---KLMITYTRKSDAGKYVCVGTNMVGE--------------------RESEVA 215

Query: 1820 KIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879
            ++  LE  S  +R  ++ V V+ +  F                  E R +P P    R +
Sbjct: 216  ELTVLERPSFVKRPSNLAVTVDDSAEF----------------KCEARGDPVPTVRWRKD 259

Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               +G++ +S  RY   +D     L I  V   D G YTC A N +G+A +S  L VQ
Sbjct: 260  ---DGELPKS--RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/92 (32%), Positives = 38/92 (41%), Gaps = 4/92 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+  Q   N   A  G         G+P P + W RK   LV      ++   Q  +  
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILW-RKDGVLVSTQDSRIK---QLENGV 473

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L I+    GD G YTC A    GEA  S YI+
Sbjct: 474 LQIRYAKLGDTGRYTCIASTPSGEATWSAYIE 505



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 16/138 (11%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L+I      D G+Y+C A N  G+AE S  L    +   + P F    ++ + +  G++ 
Sbjct: 276  LKIRKVTAGDMGSYTCVAENMVGKAEASATLTV--QVGSEPPHFVVKPRD-QVVALGRTV 332

Query: 3168 HFECTVVPVDDPDMKIEWYHNG--------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
             F+C      +P   I W   G        QP + S+R  +VS  G   L I   Q  D 
Sbjct: 333  TFQCEA--TGNPQPAIFWRREGSQNLLFSYQPPQSSSRF-SVSQTG--DLTITNVQRSDV 387

Query: 3220 GEYVCRAYNKYGEDFTRA 3237
            G Y+C+  N  G   T+A
Sbjct: 388  GYYICQTLNVAGSIITKA 405



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 9/106 (8%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN-GQPVTI 1489
            +++++ + +V  +P FV RP ++   ++     F+C  E   D    V W K+ G+    
Sbjct: 210  RESEVAELTVLERPSFVKRPSNLAVTVDDS-AEFKC--EARGDPVPTVRWRKDDGELPKS 266

Query: 1490 GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             +  R  H      L I  + A D G YTC A N+VG  E S  LT
Sbjct: 267  RYEIRDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLT 307



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 7/104 (6%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ + ++P F+         V+  SA F+   E + D   TV W  +  ++  + R +  
Sbjct: 216  ELTVLERPSFVKRPSNLAVTVD-DSAEFKC--EARGDPVPTVRWRKDDGELPKS-RYEIR 271

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139
             D     L I  V A D G YT VA N  G+A+ SA++TV+  S
Sbjct: 272  DDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGS 312



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 9/96 (9%)

Query: 907  QKPEF-KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            ++P F K P    +++ +      EAR    GD    V W KD   +   SR     +  
Sbjct: 221  ERPSFVKRPSNLAVTVDDSAEFKCEAR----GDPVPTVRWRKDDGELP-KSRYEIRDDH- 274

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
               L I+ VT  D G YTC A N +G+A  SA LT+
Sbjct: 275  --TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 14/166 (8%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            P G     I W  +G  ++      T+    +++     T+ +D+G Y C  TN  G+ E
Sbjct: 155  PRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITY---TRKSDAGKYVCVGTNMVGERE 211

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
                 E  + +  ++P F     N+    D  SA F+C      DP   + W  +   + 
Sbjct: 212  ----SEVAELTVLERPSFVKRPSNLAVTVD-DSAEFKCEA--RGDPVPTVRWRKDDGELP 264

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
             S R +   D     L I      D G Y C A N  G+    AT+
Sbjct: 265  KS-RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATL 306



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 1698 QRHSAQDEV-ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
            +R S   E+ + + P F     ++ V  + +A F+      GDP   V W ++   +  S
Sbjct: 209  ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGELPKS 266

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
             R     D     L ++ V   D G+YTC A N +G+A  S+TL VQ
Sbjct: 267  -RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+   +N+     D+  F+C  E   DP   + W  ++  LP  +RY+   D +   L I
Sbjct: 225  FVKRPSNLAVTVDDSAEFKC--EARGDPVPTVRWRKDDGELPK-SRYEIRDDHT---LKI 278

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                  D G YTC A N  G A  S +L
Sbjct: 279  RKVTAGDMGSYTCVAENMVGKAEASATL 306



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 9/79 (11%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-----MTISHVR 2442
            + +G+ A  +C+    G PT  +EW++  + +E      ++H     S     + I H R
Sbjct: 40   VSKGEPATLNCKA--EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97

Query: 2443 DE--DEGVYMCRASNLLGE 2459
                DEGVY+C A N LGE
Sbjct: 98   KSRPDEGVYVCVARNYLGE 116



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 13/102 (12%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASSRFTS 687
           PP F+V  +      G  + F+   E  G+P   I W + G        Q  ++SSRF S
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF-S 370

Query: 688 IFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           + + G   L + ++   D G Y C+ ++  G   TKA L VT
Sbjct: 371 VSQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT 410



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 9/107 (8%)

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN-GKPIKT 1355
            R  +V E +TV++ P F +   N+      +   +C  +  GD    V W  + G+  K+
Sbjct: 210  RESEVAE-LTVLERPSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGELPKS 266

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +  R     D   L +  V   D G YTC A N +G+A  S  L V
Sbjct: 267  RYEIR-----DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 7/97 (7%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLV----ECNKYSMRYN-EQ 125
           PP F    ++   A G    F+ +  GNP P + W R+ +  +    +  + S R++  Q
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 373

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           TGD  L I  +   D G Y C   N  G  I   Y++
Sbjct: 374 TGD--LTITNVQRSDVGYYICQTLNVAGSIITKAYLE 408



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 6/93 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   PS+L ++ + SA F+C      D    V W  +   L   SR +  +D     L
Sbjct: 223  PSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGEL-PKSRYEIRDDH---TL 276

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            +I  V   D G YTC A N  G+A  S  L V+
Sbjct: 277  KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/115 (30%), Positives = 48/115 (41%), Gaps = 14/115 (12%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK--LL-----PSGHRYR 3879
            S PP F+ + +   V     V F+C  E   +P+  I W R G   LL     P      
Sbjct: 312  SEPPHFVVKPRDQVVALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 369

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVP 3934
            +V   G   L I  V   D G YIC+ +N  G   TKA +   ++ D+I     P
Sbjct: 370  SVSQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYL---EVTDVIADRPPP 419



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLR------- 2708
            +G+   L  + E R  P   IEW+K G  + T      +    L + S+  LR       
Sbjct: 42   KGEPATLNCKAEGRPTPT--IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99

Query: 2709 NDDSGIYTCKATNLLGEAVS-TASIKI 2734
              D G+Y C A N LGEAVS  AS+++
Sbjct: 100  RPDEGVYVCVARNYLGEAVSHNASLEV 126



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 4/73 (5%)

Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNL 2722
            E + E R DP   + W K+   L   +R +   D    TL I  +   D G YTC A N+
Sbjct: 241  EFKCEARGDPVPTVRWRKDDGELPK-SRYEIRDDH---TLKIRKVTAGDMGSYTCVAENM 296

Query: 2723 LGEAVSTASIKIE 2735
            +G+A ++A++ ++
Sbjct: 297  VGKAEASATLTVQ 309



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 6/91 (6%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F+ +  +  V   +   F+C  E + DP   + W ++   LP   RY    D    +L
Sbjct: 223  PSFVKRPSNLAVTVDDSAEFKC--EARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TL 276

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
             I  V A D G Y C A N  G+    AT++
Sbjct: 277  KIRKVTAGDMGSYTCVAENMVGKAEASATLT 307



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 2/74 (2%)

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
            F    +  G P   + W ++GV +   +      + G   L ++Y    D+G YTC A  
Sbjct: 436  FVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIAST 493

Query: 1790 ELGEAVTSSTLFVQ 1803
              GEA  S+ + VQ
Sbjct: 494  PSGEATWSAYIEVQ 507



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 11/107 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTL--- 3747
            PPR  VE   ++ V +G P   +C+ E  G PT  I+W+  G    T     R H +   
Sbjct: 28   PPRI-VEHPSDLIVSKGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84

Query: 3748 -NDFGFIALDIDYIYARDAGEYTCRATNKWGSATT-TAKITCSAKRD 3792
                 F+ +        D G Y C A N  G A +  A +  +  RD
Sbjct: 85   SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRD 131



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT------GSRVKTIN 3610
            PP     PSDLI+S+   A   C+       +  +EW+  G+ + T        R+   +
Sbjct: 28   PPRIVEHPSDLIVSKGEPATLNCK--AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85

Query: 3611 DFGFVILEIGGVYQR-DAGLYTCKATNRHGEA 3641
               F +  + G   R D G+Y C A N  GEA
Sbjct: 86   GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEA 117



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 5/82 (6%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   +E Q  PR  P   I W K+G  L      + T   G   L I   R  D+G Y 
Sbjct: 145  GEPAVMECQ-PPRGHPEPTISWKKDGSPLDDKDE-RITIRGG--KLMITYTRKSDAGKYV 200

Query: 2717 CKATNLLGEAVS-TASIKIEDR 2737
            C  TN++GE  S  A + + +R
Sbjct: 201  CVGTNMVGERESEVAELTVLER 222



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            E    ECQ  P G P   + W  +G PL  K+    I   G + + +      D+G+Y+C
Sbjct: 146  EPAVMECQ-PPRGHPEPTISWKKDGSPLDDKDERITIRG-GKLMITY--TRKSDAGKYVC 201

Query: 4049 RATNLYGMDETK-AVIKTTGKPGIV 4072
              TN+ G  E++ A +    +P  V
Sbjct: 202  VGTNMVGERESEVAELTVLERPSFV 226



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-----GYVALDILYTY 2175
            + +G+ A   C+ E    P  TI+W+  G+++        +H           L I++  
Sbjct: 40   VSKGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97

Query: 2176 AE--DSGTYMCKATNKLGEAV-NTCTLKVA 2202
                D G Y+C A N LGEAV +  +L+VA
Sbjct: 98   KSRPDEGVYVCVARNYLGEAVSHNASLEVA 127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 10/92 (10%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT------GHRFR-PAYEFDYVALDLLSVY 1376
            +G    L C+ +  G  T  +EW+  G+ ++T       HR   P+    ++ +      
Sbjct: 42   KGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99

Query: 1377 PEDSGVYTCQATNQLGEAVT-SCALRVIAKKD 1407
              D GVY C A N LGEAV+ + +L V   +D
Sbjct: 100  RPDEGVYVCVARNYLGEAVSHNASLEVAILRD 131



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 7/110 (6%)

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
           +  E  E    +RP F++   +L    +  +A F+ +     DP   V W KD   +  S
Sbjct: 210 RESEVAELTVLERPSFVKRPSNLAVTVDD-SAEFKCEAR--GDPVPTVRWRKDDGELPKS 266

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
                  +    +L I  + A D GSYT  A N +G+A ++A++ V   S
Sbjct: 267 RYEIRDDH----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGS 312



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 17/121 (14%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG--------RPVE 953
            V   ++ P F    +DQ+ +  G    F+   E  G+    + W ++G        +P +
Sbjct: 308  VQVGSEPPHFVVKPRDQV-VALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQ 364

Query: 954  ASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            +SSR +         LTI +V   D G+Y C+  N  G   T A L +    D+IA+   
Sbjct: 365  SSSRFSVSQTGD---LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT---DVIADRPP 418

Query: 1014 P 1014
            P
Sbjct: 419  P 419



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/40 (37%), Positives = 19/40 (47%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            PP FV  P    V  G    F C  TG+P+P + W   G+
Sbjct: 314  PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS 353


>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
          Length = 1607

 Score =  104 bits (249), Expect = 9e-21
 Identities = 109/414 (26%), Positives = 162/414 (39%), Gaps = 45/414 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI---KNSPDFQIHTFSTKS 4466
            PP   +      V + E A    + +G P P I+WY+    +   K+ P        + S
Sbjct: 28   PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 87

Query: 4467 ILIIRQVFVE----DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            +  +R V       D  V+  VA N  G A  S N  +E         I+   F     +
Sbjct: 88   LFFLRIVHGRKSRPDEGVYVCVARNYLGEA-VSHNASLEV-------AILRDDFRQNPSD 139

Query: 4523 VNVTSGQLVRLDTK-VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            V V  G+   ++ +   G     + W K+G  +  D   +I    G   L+I      D+
Sbjct: 140  VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG--KLMITYTRKSDA 196

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            GKY CV  N  GE   +   V  L   +             P  ++   +  V    + E
Sbjct: 197  GKYVCVGTNMVGERESE---VAELTVLE------------RPSFVKRPSNLAVTVDDSAE 241

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            F C+  G P+PTV+W K D  +  S+Y       D++TL+I +    D G Y CVA N  
Sbjct: 242  FKCEARGDPVPTVRWRKDDGELPKSRY----EIRDDHTLKIRKVTAGDMGSYTCVAENMV 297

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-- 4759
            G+   +A L V    +  +   + P RD VV  G+   F+ + T   +P I W REG+  
Sbjct: 298  GKAEASATLTVQVGSEPPHF-VVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQN 355

Query: 4760 -LIPETP--DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L    P              L I N    D G + C+    AG + T A L V
Sbjct: 356  LLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 409



 Score =  103 bits (246), Expect = 2e-20
 Identities = 106/387 (27%), Positives = 160/387 (41%), Gaps = 47/387 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W ++  P+ +  D +I     K  L+I      D+  +  V  N  G  +  
Sbjct: 157  GHPEPTISWKKDGSPLDDK-DERITIRGGK--LMITYTRKSDAGKYVCVGTNMVGERESE 213

Query: 4496 -ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
             A L V E+          PSF     N+ VT         +  G     V W K+  ++
Sbjct: 214  VAELTVLER----------PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL 263

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             P  R +I ++   +TL I +    D G Y CVA N  G+A   A   V +         
Sbjct: 264  -PKSRYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--------- 310

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLI-------KPS 4666
                 + PP  +   +D++VA G+ + F C+  G P P + W + G + +       + S
Sbjct: 311  ----GSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSS 366

Query: 4667 KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ--PDQADNLPAL 4724
              F +S+T D   L I+     D G Y C   N AG +   A L+VT    D+   +   
Sbjct: 367  SRFSVSQTGD---LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ 423

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
             P+   V  +G         T    PTI W ++G L+  T D   I +  N VL I    
Sbjct: 424  GPVNQTVAVDG-TFVLSCVATGSPVPTILWRKDGVLV-STQD-SRIKQLENGVLQIRYAK 480

Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVVK 4811
              DTG +TC A+T +G+   SA + V+
Sbjct: 481  LGDTGRYTCIASTPSGEATWSAYIEVQ 507



 Score = 96.3 bits (229), Expect = 2e-18
 Identities = 81/309 (26%), Positives = 128/309 (41%), Gaps = 28/309 (9%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F K+     V   + A F+ E  G+P+P ++W +++  +  S  ++I    T   L I
Sbjct: 223  PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHT---LKI 278

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            R+V   D   +  VAEN  G A+ SA L V+        G  PP F +  ++  V  G+ 
Sbjct: 279  RKVTAGDMGSYTCVAENMVGKAEASATLTVQV-------GSEPPHFVVKPRDQVVALGRT 331

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKK-----VQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            V    + TG     ++W + G +      QP   +       T  L I      D G Y 
Sbjct: 332  VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C  +N AG     A   V+     D+P P  +          P+   +  +G  +  SC 
Sbjct: 392  CQTLNVAGSIITKAYLEVT-DVIADRPPPVIRQG--------PVNQTVAVDGTFV-LSCV 441

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              G P+PT+ W K   L+  S      +  +   L+I  A   D G Y C+A   +G  T
Sbjct: 442  ATGSPVPTILWRKDGVLV--STQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 499

Query: 4706 VAAKLKVTQ 4714
             +A ++V +
Sbjct: 500  WSAYIEVQE 508



 Score = 82.2 bits (194), Expect = 4e-14
 Identities = 79/316 (25%), Positives = 119/316 (37%), Gaps = 39/316 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP+I + P +  + +G  A    +  G P P + W+K G+R+                  
Sbjct: 28  PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERV------------------ 69

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
              T K D   + +L  + +   +   +     P E         Y+ +         + 
Sbjct: 70  --ETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVA 127

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVN 443
           I    L   F +   D  V  G+    +C+   G P P ++W   D    DD + +I + 
Sbjct: 128 I----LRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWK-KDGSPLDDKDERITIR 182

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ-CRLNVIEKEQVVAPKFVERFSTLNV 502
                 LMIT    SD+G   CV  N  GE   +   L V+E+     P FV+R S L V
Sbjct: 183 GG---KLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLER-----PSFVKRPSNLAV 234

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              +       A G P P + W+KD    +P     I  D    TL I +  A D   Y 
Sbjct: 235 TVDDSAEFKCEARGDPVPTVRWRKDDGE-LPKSRYEIRDD---HTLKIRKVTAGDMGSYT 290

Query: 563 CTAQNVAGSTATRARL 578
           C A+N+ G     A L
Sbjct: 291 CVAENMVGKAEASATL 306



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 58/193 (30%), Positives = 89/193 (46%), Gaps = 13/193 (6%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR----DDYNHKI 440
           + ++   P+ V+   D  V++G+    +C+  GRP P + W+    ++     D  +H++
Sbjct: 22  LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81

Query: 441 LVNESGNHALMITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498
           L+       L I +   S  D GV  CVARN  GE       N   +  ++   F +  S
Sbjct: 82  LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH---NASLEVAILRDDFRQNPS 138

Query: 499 TLNVREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
            + V  GEP V+  +   G P P I+W+KDG P+    E RI   GG   L I   + SD
Sbjct: 139 DVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDE-RITIRGG--KLMITYTRKSD 195

Query: 558 AAWYQCTAQNVAG 570
           A  Y C   N+ G
Sbjct: 196 AGKYVCVGTNMVG 208



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 61/206 (29%), Positives = 82/206 (39%), Gaps = 14/206 (6%)

Query: 380 EERIEISEKALA--PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
           E   E++E  +   P FVK   +  VT      F C   G P P V W  +D ++     
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-R 267

Query: 438 HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
           ++I      +H L I  VT  D G  TCVA N  G+      L V    +   P FV + 
Sbjct: 268 YEI----RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSE--PPHFVVKP 321

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPII-----PNPELRIHTDGGASTLDIPR 552
               V  G  V     A G P P I W+++G   +     P       +      L I  
Sbjct: 322 RDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITN 381

Query: 553 AKASDAAWYQCTAQNVAGSTATRARL 578
            + SD  +Y C   NVAGS  T+A L
Sbjct: 382 VQRSDVGYYICQTLNVAGSIITKAYL 407



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 67/293 (22%), Positives = 117/293 (39%), Gaps = 16/293 (5%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F +   N       +A+F+ + RG+P P V W +    L + ++Y +R      D +L
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPK-SRYEIR-----DDHTL 276

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE-GXXXXXXXXXXXXXYRHVSETVEHKA 190
            I+++  GD G YTC A N  G+A  S  +  + G                +  TV  + 
Sbjct: 277 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQC 336

Query: 191 YGT---QGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLR----EVSFRESITKR 243
             T   Q     +   +Q + ++     SS+      T +  +      +V +    T  
Sbjct: 337 EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLN 396

Query: 244 YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
             G    +   E+   +    PP I Q P N  +            +G+P P + W K+G
Sbjct: 397 VAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDG 456

Query: 304 QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
             ++ S +   I    +  L++R  +  D+G YT +A  P+G    S Y+ V+
Sbjct: 457 --VLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507



 Score = 68.9 bits (161), Expect = 4e-10
 Identities = 62/196 (31%), Positives = 86/196 (43%), Gaps = 19/196 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ-IRDDY-----NHKILVNES 445
           P FV   +D+ V  G+   F C  TG P P + W     Q +   Y     + +  V+++
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 374

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLN-- 501
           G+  L ITNV  SD G   C   N +G    +  L V +   V+A  P  V R   +N  
Sbjct: 375 GD--LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD---VIADRPPPVIRQGPVNQT 429

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-HTDGGASTLDIPRAKASDAAW 560
           V      VL+  A G+P P I W+KDGV ++   + RI   + G   L I  AK  D   
Sbjct: 430 VAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENG--VLQIRYAKLGDTGR 486

Query: 561 YQCTAQNVAGSTATRA 576
           Y C A   +G     A
Sbjct: 487 YTCIASTPSGEATWSA 502



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 77/308 (25%), Positives = 119/308 (38%), Gaps = 35/308 (11%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-----PDIRNKILEEDG 4567
            PP       ++ V+ G+   L+ K  G     + W K G++V+     P     +L    
Sbjct: 28   PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGS 87

Query: 4568 TYTLLILEAYPQ--DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
             + L I+       D G Y CVA N  GEA       VS  A+        + A    + 
Sbjct: 88   LFFLRIVHGRKSRPDEGVYVCVARNYLGEA-------VSHNAS-------LEVAILRDDF 133

Query: 4626 IEPLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
             +   D +VA G+     C+   G P PT+ W K      P        T     L I+ 
Sbjct: 134  RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDG---SPLDDKDERITIRGGKLMITY 190

Query: 4685 AFPEDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                D G Y CV  N  G R +  A+L V +       P+     ++ V     A+FK +
Sbjct: 191  TRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPS-----NLAVTVDDSAEFKCE 245

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                  PT++W ++   +P++         ++  L I      D G++TC A    G+ E
Sbjct: 246  ARGDPVPTVRWRKDDGELPKS----RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAE 301

Query: 4804 TSAKLVVK 4811
             SA L V+
Sbjct: 302  ASATLTVQ 309



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 99/435 (22%), Positives = 158/435 (36%), Gaps = 49/435 (11%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P +SW +  +PL + ++   R   + G   L+I      D G+Y C   N  GE 
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDE---RITIRGG--KLMITYTRKSDAGKYVCVGTNMVGER 210

Query: 156 ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDH 215
              V  +                   V ++ E K    +G      R  +       + +
Sbjct: 211 ESEV-AELTVLERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRY 268

Query: 216 SSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNS 275
              DD  +   +     ++     + +  VG+++   +  +   +G   PP    KPR+ 
Sbjct: 269 EIRDDHTLKIRKVTA-GDMGSYTCVAENMVGKAEASATLTVQ--VGS-EPPHFVVKPRDQ 324

Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNG-QRLINS----NKHEIITTHNHTTLRVRNTQK 330
            +  G    FQ + +GNP+P + W + G Q L+ S          +      L + N Q+
Sbjct: 325 VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQR 384

Query: 331 SDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKAL 390
           SD G+Y     N  G I+T  YL V       + D+    I      +T         A+
Sbjct: 385 SDVGYYICQTLNVAGSIITKAYLEV----TDVIADRPPPVIRQGPVNQT--------VAV 432

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
              FV  C    V  G            P P + W   D  +    + +I   E+G   L
Sbjct: 433 DGTFVLSC----VATGS-----------PVPTILW-RKDGVLVSTQDSRIKQLENG--VL 474

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I    L D+G  TC+A   SGE  +   + V E    V P    R +  N+    P   
Sbjct: 475 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQP---PRPTDPNLIPSAPSKP 531

Query: 511 NARAVGTPTPRITWQ 525
               V   T  ++WQ
Sbjct: 532 EVTDVSRNTVTLSWQ 546



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 75/312 (24%), Positives = 114/312 (36%), Gaps = 18/312 (5%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT- 126
           E  PP   +   +   ++G  A    K  G PTP + W  K    VE +K   R +    
Sbjct: 25  EDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWY-KGGERVETDKDDPRSHRMLL 83

Query: 127 GDVSLLIKQIGPG-----DEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRH 181
              SL   +I  G     DEG Y C ARN  GEA+                         
Sbjct: 84  PSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVA 143

Query: 182 VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
           V E    +    +G+        +  +  +  D   T         Y    +      + 
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVG 203

Query: 242 KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
              VGE + +++      L  +  P   ++P N  +     A+F+ +  G+P P V W K
Sbjct: 204 TNMVGERESEVA-----ELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRK 258

Query: 302 NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE- 360
           +   L  S ++EI   H   TL++R     D G YT +AEN  G    S  L V+  +E 
Sbjct: 259 DDGELPKS-RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314

Query: 361 -SYVQDQRSQYI 371
             +V   R Q +
Sbjct: 315 PHFVVKPRDQVV 326



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 64/242 (26%), Positives = 85/242 (35%), Gaps = 18/242 (7%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE---NFPIKNSPDFQIHTFST 4464
            S+PP F  K +   V       F+ E  G P P I W RE   N      P      FS 
Sbjct: 312  SEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV 371

Query: 4465 KSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
                 L I  V   D   +     N  G+    A L V +          PP       N
Sbjct: 372  SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR----PPPVIRQGPVN 427

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEAYPQDS 4581
              V       L    TG+    + W K+G  V   D R K LE      L I  A   D+
Sbjct: 428  QTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG---VLQIRYAKLGDT 484

Query: 4582 GKYECVAINSAGEARCDAECVV---SLPATKDKPKPQTKAANAP--PEIIEPLKDKIVAE 4636
            G+Y C+A   +GEA   A   V    +P    +P       +AP  PE+ +  ++ +   
Sbjct: 485  GRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLS 544

Query: 4637 GQ 4638
             Q
Sbjct: 545  WQ 546



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 7/97 (7%)

Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-----IPNPELRI 539
           +++   P+ VE  S L V +GEP  LN +A G PTP I W K G  +      P     +
Sbjct: 23  RQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRML 82

Query: 540 HTDGGASTLDIPRAKAS--DAAWYQCTAQNVAGSTAT 574
              G    L I   + S  D   Y C A+N  G   +
Sbjct: 83  LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 119



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 91/354 (25%), Positives = 135/354 (38%), Gaps = 93/354 (26%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL---TVYGE 1912
            +S+G+ A   C+ E  P P   +EWY  G+ +++      S+     +  +     V+G 
Sbjct: 40   VSKGEPATLNCKAEGRPTPT--IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97

Query: 1913 ----DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAV 1968
                D G Y C A N LG+AVS                 H ++LE +  L DD  +++  
Sbjct: 98   KSRPDEGVYVCVARNYLGEAVS-----------------HNASLE-VAILRDD--FRQNP 137

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
             D    V +P     +   +   GHP           +PT  + W  +G P+      + 
Sbjct: 138  SDVMVAVGEP----AVMECQPPRGHP-----------EPT--ISWKKDGSPLDDKDE-RI 179

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKI 2088
            T   G   L I Y    D G Y+C  TN VGE                       R  ++
Sbjct: 180  TIRGG--KLMITYTRKSDAGKYVCVGTNMVGE-----------------------RESEV 214

Query: 2089 QELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW-FH 2147
             EL   ERP  +      +RP  L            D A F+C  E   DP  T+ W   
Sbjct: 215  AELTVLERPSFV------KRPSNLAVTVD-------DSAEFKC--EARGDPVPTVRWRKD 259

Query: 2148 NGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +G+  ++ +  R  H      L I    A D G+Y C A N +G+A  + TL V
Sbjct: 260  DGELPKSRYEIRDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 50/196 (25%), Positives = 78/196 (39%), Gaps = 24/196 (12%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA------SHRIRTV 3100
            PP       D++ +S+G+ A         G  +  IEW+  G+ +E       SHR+   
Sbjct: 28   PPRIVEHPSDLI-VSKGEPATLNCKA--EGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84

Query: 3101 YAFGMVVLEILGTKTT-DSGTYSCRATNKWGQA---EISVKLECVDKSKGQKPRFTTHIQ 3156
                  +  + G K+  D G Y C A N  G+A     S+++  +     Q P       
Sbjct: 85   SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVM--- 141

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
                +  G+ A  EC   P   P+  I W  +G P+       T+     +   I YT+ 
Sbjct: 142  ----VAVGEPAVMECQP-PRGHPEPTISWKKDGSPLDDKDERITIRGGKLM---ITYTRK 193

Query: 3217 HDSGEYVCRAYNKYGE 3232
             D+G+YVC   N  GE
Sbjct: 194  SDAGKYVCVGTNMVGE 209



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 61/238 (25%), Positives = 94/238 (39%), Gaps = 48/238 (20%)

Query: 1700 HSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            H+A  EV      F     D+ VA  + A  E +  P G P+  + W ++G P++  +  
Sbjct: 120  HNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQP-PRGHPEPTISWKKDGSPLDDKDER 178

Query: 1760 TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
             T+       L + Y    D+G Y C   N +GE                     ES + 
Sbjct: 179  ITIRGG---KLMITYTRKSDAGKYVCVGTNMVGE--------------------RESEVA 215

Query: 1820 KIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879
            ++  LE  S  +R  ++ V V+ +  F                  E R +P P    R +
Sbjct: 216  ELTVLERPSFVKRPSNLAVTVDDSAEF----------------KCEARGDPVPTVRWRKD 259

Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               +G++ +S  RY   +D     L I  V   D G YTC A N +G+A +S  L VQ
Sbjct: 260  ---DGELPKS--RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/92 (32%), Positives = 38/92 (41%), Gaps = 4/92 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+  Q   N   A  G         G+P P + W RK   LV      ++   Q  +  
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILW-RKDGVLVSTQDSRIK---QLENGV 473

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L I+    GD G YTC A    GEA  S YI+
Sbjct: 474 LQIRYAKLGDTGRYTCIASTPSGEATWSAYIE 505



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 16/138 (11%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L+I      D G+Y+C A N  G+AE S  L    +   + P F    ++ + +  G++ 
Sbjct: 276  LKIRKVTAGDMGSYTCVAENMVGKAEASATLTV--QVGSEPPHFVVKPRD-QVVALGRTV 332

Query: 3168 HFECTVVPVDDPDMKIEWYHNG--------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
             F+C      +P   I W   G        QP + S+R  +VS  G   L I   Q  D 
Sbjct: 333  TFQCEA--TGNPQPAIFWRREGSQNLLFSYQPPQSSSRF-SVSQTG--DLTITNVQRSDV 387

Query: 3220 GEYVCRAYNKYGEDFTRA 3237
            G Y+C+  N  G   T+A
Sbjct: 388  GYYICQTLNVAGSIITKA 405



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 9/106 (8%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN-GQPVTI 1489
            +++++ + +V  +P FV RP ++   ++     F+C  E   D    V W K+ G+    
Sbjct: 210  RESEVAELTVLERPSFVKRPSNLAVTVDDS-AEFKC--EARGDPVPTVRWRKDDGELPKS 266

Query: 1490 GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             +  R  H      L I  + A D G YTC A N+VG  E S  LT
Sbjct: 267  RYEIRDDH-----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLT 307



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 7/104 (6%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            E+ + ++P F+         V+  SA F+   E + D   TV W  +  ++  + R +  
Sbjct: 216  ELTVLERPSFVKRPSNLAVTVD-DSAEFKC--EARGDPVPTVRWRKDDGELPKS-RYEIR 271

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139
             D     L I  V A D G YT VA N  G+A+ SA++TV+  S
Sbjct: 272  DDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGS 312



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 9/96 (9%)

Query: 907  QKPEF-KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            ++P F K P    +++ +      EAR    GD    V W KD   +   SR     +  
Sbjct: 221  ERPSFVKRPSNLAVTVDDSAEFKCEAR----GDPVPTVRWRKDDGELP-KSRYEIRDDH- 274

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
               L I+ VT  D G YTC A N +G+A  SA LT+
Sbjct: 275  --TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 14/166 (8%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            P G     I W  +G  ++      T+    +++     T+ +D+G Y C  TN  G+ E
Sbjct: 155  PRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITY---TRKSDAGKYVCVGTNMVGERE 211

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
                 E  + +  ++P F     N+    D  SA F+C      DP   + W  +   + 
Sbjct: 212  ----SEVAELTVLERPSFVKRPSNLAVTVD-DSAEFKCEA--RGDPVPTVRWRKDDGELP 264

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
             S R +   D     L I      D G Y C A N  G+    AT+
Sbjct: 265  KS-RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATL 306



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 1698 QRHSAQDEV-ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
            +R S   E+ + + P F     ++ V  + +A F+      GDP   V W ++   +  S
Sbjct: 209  ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGELPKS 266

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
             R     D     L ++ V   D G+YTC A N +G+A  S+TL VQ
Sbjct: 267  -RYEIRDDH---TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+   +N+     D+  F+C  E   DP   + W  ++  LP  +RY+   D +   L I
Sbjct: 225  FVKRPSNLAVTVDDSAEFKC--EARGDPVPTVRWRKDDGELPK-SRYEIRDDHT---LKI 278

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                  D G YTC A N  G A  S +L
Sbjct: 279  RKVTAGDMGSYTCVAENMVGKAEASATL 306



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 9/79 (11%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-----MTISHVR 2442
            + +G+ A  +C+    G PT  +EW++  + +E      ++H     S     + I H R
Sbjct: 40   VSKGEPATLNCKA--EGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97

Query: 2443 DE--DEGVYMCRASNLLGE 2459
                DEGVY+C A N LGE
Sbjct: 98   KSRPDEGVYVCVARNYLGE 116



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 13/102 (12%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASSRFTS 687
           PP F+V  +      G  + F+   E  G+P   I W + G        Q  ++SSRF S
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF-S 370

Query: 688 IFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           + + G   L + ++   D G Y C+ ++  G   TKA L VT
Sbjct: 371 VSQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT 410



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 9/107 (8%)

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN-GKPIKT 1355
            R  +V E +TV++ P F +   N+      +   +C  +  GD    V W  + G+  K+
Sbjct: 210  RESEVAE-LTVLERPSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGELPKS 266

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +  R     D   L +  V   D G YTC A N +G+A  S  L V
Sbjct: 267  RYEIR-----DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 7/97 (7%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLV----ECNKYSMRYN-EQ 125
           PP F    ++   A G    F+ +  GNP P + W R+ +  +    +  + S R++  Q
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 373

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           TGD  L I  +   D G Y C   N  G  I   Y++
Sbjct: 374 TGD--LTITNVQRSDVGYYICQTLNVAGSIITKAYLE 408



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 6/93 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   PS+L ++ + SA F+C      D    V W  +   L   SR +  +D     L
Sbjct: 223  PSFVKRPSNLAVTVDDSAEFKCEAR--GDPVPTVRWRKDDGEL-PKSRYEIRDDH---TL 276

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            +I  V   D G YTC A N  G+A  S  L V+
Sbjct: 277  KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/115 (30%), Positives = 48/115 (41%), Gaps = 14/115 (12%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK--LL-----PSGHRYR 3879
            S PP F+ + +   V     V F+C  E   +P+  I W R G   LL     P      
Sbjct: 312  SEPPHFVVKPRDQVVALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 369

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVP 3934
            +V   G   L I  V   D G YIC+ +N  G   TKA +   ++ D+I     P
Sbjct: 370  SVSQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYL---EVTDVIADRPPP 419



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLR------- 2708
            +G+   L  + E R  P   IEW+K G  + T      +    L + S+  LR       
Sbjct: 42   KGEPATLNCKAEGRPTPT--IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99

Query: 2709 NDDSGIYTCKATNLLGEAVS-TASIKI 2734
              D G+Y C A N LGEAVS  AS+++
Sbjct: 100  RPDEGVYVCVARNYLGEAVSHNASLEV 126



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 4/73 (5%)

Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNL 2722
            E + E R DP   + W K+   L   +R +   D    TL I  +   D G YTC A N+
Sbjct: 241  EFKCEARGDPVPTVRWRKDDGELPK-SRYEIRDDH---TLKIRKVTAGDMGSYTCVAENM 296

Query: 2723 LGEAVSTASIKIE 2735
            +G+A ++A++ ++
Sbjct: 297  VGKAEASATLTVQ 309



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 6/91 (6%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F+ +  +  V   +   F+C  E + DP   + W ++   LP   RY    D    +L
Sbjct: 223  PSFVKRPSNLAVTVDDSAEFKC--EARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TL 276

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
             I  V A D G Y C A N  G+    AT++
Sbjct: 277  KIRKVTAGDMGSYTCVAENMVGKAEASATLT 307



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 2/74 (2%)

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
            F    +  G P   + W ++GV +   +      + G   L ++Y    D+G YTC A  
Sbjct: 436  FVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIAST 493

Query: 1790 ELGEAVTSSTLFVQ 1803
              GEA  S+ + VQ
Sbjct: 494  PSGEATWSAYIEVQ 507



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 11/107 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS---RVHTL--- 3747
            PPR  VE   ++ V +G P   +C+ E  G PT  I+W+  G    T     R H +   
Sbjct: 28   PPRI-VEHPSDLIVSKGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84

Query: 3748 -NDFGFIALDIDYIYARDAGEYTCRATNKWGSATT-TAKITCSAKRD 3792
                 F+ +        D G Y C A N  G A +  A +  +  RD
Sbjct: 85   SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRD 131



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 9/92 (9%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT------GSRVKTIN 3610
            PP     PSDLI+S+   A   C+       +  +EW+  G+ + T        R+   +
Sbjct: 28   PPRIVEHPSDLIVSKGEPATLNCK--AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85

Query: 3611 DFGFVILEIGGVYQR-DAGLYTCKATNRHGEA 3641
               F +  + G   R D G+Y C A N  GEA
Sbjct: 86   GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEA 117



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 5/82 (6%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   +E Q  PR  P   I W K+G  L      + T   G   L I   R  D+G Y 
Sbjct: 145  GEPAVMECQ-PPRGHPEPTISWKKDGSPLDDKDE-RITIRGG--KLMITYTRKSDAGKYV 200

Query: 2717 CKATNLLGEAVS-TASIKIEDR 2737
            C  TN++GE  S  A + + +R
Sbjct: 201  CVGTNMVGERESEVAELTVLER 222



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            E    ECQ  P G P   + W  +G PL  K+    I   G + + +      D+G+Y+C
Sbjct: 146  EPAVMECQ-PPRGHPEPTISWKKDGSPLDDKDERITIRG-GKLMITY--TRKSDAGKYVC 201

Query: 4049 RATNLYGMDETK-AVIKTTGKPGIV 4072
              TN+ G  E++ A +    +P  V
Sbjct: 202  VGTNMVGERESEVAELTVLERPSFV 226



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-----GYVALDILYTY 2175
            + +G+ A   C+ E    P  TI+W+  G+++        +H           L I++  
Sbjct: 40   VSKGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGR 97

Query: 2176 AE--DSGTYMCKATNKLGEAV-NTCTLKVA 2202
                D G Y+C A N LGEAV +  +L+VA
Sbjct: 98   KSRPDEGVYVCVARNYLGEAVSHNASLEVA 127



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 10/92 (10%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT------GHRFR-PAYEFDYVALDLLSVY 1376
            +G    L C+ +  G  T  +EW+  G+ ++T       HR   P+    ++ +      
Sbjct: 42   KGEPATLNCKAE--GRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99

Query: 1377 PEDSGVYTCQATNQLGEAVT-SCALRVIAKKD 1407
              D GVY C A N LGEAV+ + +L V   +D
Sbjct: 100  RPDEGVYVCVARNYLGEAVSHNASLEVAILRD 131



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 7/110 (6%)

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
           +  E  E    +RP F++   +L    +  +A F+ +     DP   V W KD   +  S
Sbjct: 210 RESEVAELTVLERPSFVKRPSNLAVTVDD-SAEFKCEAR--GDPVPTVRWRKDDGELPKS 266

Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
                  +    +L I  + A D GSYT  A N +G+A ++A++ V   S
Sbjct: 267 RYEIRDDH----TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGS 312



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 17/121 (14%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG--------RPVE 953
            V   ++ P F    +DQ+ +  G    F+   E  G+    + W ++G        +P +
Sbjct: 308  VQVGSEPPHFVVKPRDQV-VALGRTVTFQC--EATGNPQPAIFWRREGSQNLLFSYQPPQ 364

Query: 954  ASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            +SSR +         LTI +V   D G+Y C+  N  G   T A L +    D+IA+   
Sbjct: 365  SSSRFSVSQTGD---LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVT---DVIADRPP 418

Query: 1014 P 1014
            P
Sbjct: 419  P 419



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 15/40 (37%), Positives = 19/40 (47%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            PP FV  P    V  G    F C  TG+P+P + W   G+
Sbjct: 314  PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS 353


>AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein.
          Length = 2242

 Score =  103 bits (248), Expect = 1e-20
 Identities = 77/289 (26%), Positives = 120/289 (41%), Gaps = 30/289 (10%)

Query: 4458 QIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT 4517
            ++H    K  L++  V  +DS V+            CSA L V           + P FT
Sbjct: 35   KMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPS--------LAPLFT 86

Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577
               ++V V  G+  R D K++GT P  V W   G  ++     ++ ++ G ++L I    
Sbjct: 87   RLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVG 146

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP--------------- 4622
             +D G Y   A+N+ G+A C A+  V  P T     P +K    P               
Sbjct: 147  SEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASG-PSSKLEKMPSIPEEPEQGELERLS 205

Query: 4623 -PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
             P+ + PL+D  V   +     C++ G P PT+ W+     I+ S   +M++  D + L 
Sbjct: 206  IPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLV 265

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-----PDQADNLPALT 4725
                 P+  G YK V  N  G+    A L VT      PD A  + A+T
Sbjct: 266  FPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVT 314



 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 98/441 (22%), Positives = 179/441 (40%), Gaps = 23/441 (5%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            E  R   S  ++++E      E   +G ++    P F + +Q   V   ++A  E +  G
Sbjct: 173  EEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTG 232

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
             P P I W+     I++S D ++  +     L+   V  + + V+ +V  N+ G A C A
Sbjct: 233  LPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYA 292

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
            +L V +        +VP       Q V VT G++V L    T   P  +    +   +  
Sbjct: 293  HLYVTD--------VVPGPPDGAPQVVAVT-GRMVTL----TWNPPRSLDMAIDPDSLTY 339

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
             +++++L  D    L+     P  +       +              S P+   +P    
Sbjct: 340  TVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLL 399

Query: 4617 K---AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV-QWYKGDKLIKPSKYFQMS 4672
            +        P +++      V EGQ    +          V +  +G  L   +  +++S
Sbjct: 400  EHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEARAGVYELS 459

Query: 4673 RTAD-EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
            +  D +Y LRI      D G   C A N  G  T +  L++ +  + +++     + D+ 
Sbjct: 460  QPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESI-----MEDVE 514

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
            V  G+ A+F   +  K  P I W ++  L+ E+     ++E N   L++ +T  +D G +
Sbjct: 515  VGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVY 574

Query: 4792 TCRATTAAGQVETSAKLVVKS 4812
            TC A   AG+V   A+L V S
Sbjct: 575  TCTAQNLAGEVSCKAELAVHS 595



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 61/221 (27%), Positives = 95/221 (42%), Gaps = 21/221 (9%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V+PS  P+FT+ ++   V E   ARF+ +  G P P++ W     P++ S + ++     
Sbjct: 77   VRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGG 136

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG--------GIVP--- 4513
               L I  V  ED  ++A  A N  G A CSA L VEE R    G          +P   
Sbjct: 137  LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEP 196

Query: 4514 ----------PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                      P F    Q++ V   +   L+ +VTG     + W  NG ++Q     ++ 
Sbjct: 197  EQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMT 256

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            +    + L+     PQ +G Y+ V  N  G+A C A   V+
Sbjct: 257  QYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVT 297



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 63/227 (27%), Positives = 101/227 (44%), Gaps = 12/227 (5%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP+FT  ++D+ V E +AA F+ ++   G P   V W   G P+E S  L    D G  +
Sbjct: 82   APLFTRLLEDVEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 139

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829
            L++ +V  ED G Y   A+N  G+A  S+ L+V+   +    S   S L+K+  + +   
Sbjct: 140  LHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRT--AASGPSSKLEKMPSIPEEPE 197

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
                E + +     P F+  L    ++   + A  EC++   P P   + W+ NG  +QS
Sbjct: 198  QGELERLSI-----PDFLRPLQ-DLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQS 249

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
                R +       L    V  + +G Y     N LG+A     L V
Sbjct: 250  SDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 296



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 3/223 (1%)

Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           P   P   +   + ++ EG  A+F  ++SG P P VTW   G  +  S    +       
Sbjct: 79  PSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLH 138

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
           +L + +    D G Y + A N +G    S  L VE P  +      S+        E  E
Sbjct: 139 SLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTA-ASGPSSKLEKMPSIPEEPE 197

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
           + E+ E+   P F++  QD +V   K    +C+VTG PYP ++WF N  +I+   + + +
Sbjct: 198 QGEL-ERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRR-M 255

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
                 H L+   V    +GV   V  NK G+ A    L V +
Sbjct: 256 TQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTD 298



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 52/174 (29%), Positives = 73/174 (41%), Gaps = 3/174 (1%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G+M  F+C V G    EV W    R ++       +  +     L++T+V   DSGV TC
Sbjct: 1   GEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTC 60

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
                  E     RL V      +AP F      + V EG     + +  GTP P +TW 
Sbjct: 61  KLSTAKDELTCSARLTV---RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWT 117

Query: 526 KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             G P+  +  LR+  DGG  +L I    + D   Y  +A N  G     A+LY
Sbjct: 118 HFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLY 171



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 41/269 (15%)

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT-LLILEAYPQDSGKYEC 4586
            G++   +  V G   ++V WL  G+ +QP +    +  DG    LL+   +  DSG Y C
Sbjct: 1    GEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTC 60

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
                +  E  C A   V         +P     +  P     L+D  V EG+A  F CKI
Sbjct: 61   KLSTAKDELTCSARLTV---------RP-----SLAPLFTRLLEDVEVLEGRAARFDCKI 106

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G P P V W      ++ S+  ++ +    ++L I+    EDEG Y   A N+ G+   
Sbjct: 107  SGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHC 166

Query: 4707 AAKLKVTQPDQADNLPA--------------------------LTPLRDIVVYEGQPAQF 4740
            +A+L V +P  A + P+                          L PL+D+ V   + A  
Sbjct: 167  SAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAML 226

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQM 4769
            + Q+T    PTI W   G  I  + D +M
Sbjct: 227  ECQVTGLPYPTISWFHNGHRIQSSDDRRM 255



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 72/317 (22%), Positives = 138/317 (43%), Gaps = 24/317 (7%)

Query: 3063 GQIAHYEASLIPTGDQSMVIEWFYNGKTIE-ASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121
            G++A +E   +  G   + ++W   G+ ++ A  + +  +      L +      DSG Y
Sbjct: 1    GEMALFEC--LVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVY 58

Query: 3122 SCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181
            +C+ +    +   S +L          P FT  ++++E L +G++A F+C +     P  
Sbjct: 59   TCKLSTAKDELTCSARLTV---RPSLAPLFTRLLEDVEVL-EGRAARFDCKISGTPPP-- 112

Query: 3182 KIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINC 3241
             + W H G PM  S  ++   D G   L IA+  + D G Y   A N +G+       +C
Sbjct: 113  VVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQ------AHC 166

Query: 3242 YGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP---PKFITQIQDVTKLVEGQ 3298
              +  +Y+E  +  +     +LE +    ++ P     E    P F+  +QD+ ++   +
Sbjct: 167  SAQ--LYVEEPRTAASGPSSKLEKMPSIPEE-PEQGELERLSIPDFLRPLQDL-EVGLAK 222

Query: 3299 SAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECV 3358
             A  E ++  +  P   + WF+NG ++      R      +  L       +++G Y+ V
Sbjct: 223  EAMLECQVTGLPYP--TISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSV 280

Query: 3359 ATNKLGRDSTKANLKCT 3375
              NKLG+ +  A+L  T
Sbjct: 281  IANKLGKAACYAHLYVT 297



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 64/226 (28%), Positives = 96/226 (42%), Gaps = 12/226 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P+F + L +   V EG+    +C++   G P   V W H G  +      +   D G  +
Sbjct: 83   PLFTRLLEDVE-VLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 139

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I H  S D G Y V AVN  G AH SA + V E     +   ++  +E++  + +   
Sbjct: 140  LHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSK--LEKMPSIPEEPE 197

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            + +  R     +  P F R L ++E        LEC  Q  G     + WF NG  I++ 
Sbjct: 198  QGELER-----LSIPDFLRPLQDLEVGLAKEAMLEC--QVTGLPYPTISWFHNGHRIQSS 250

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
               R     D   L   +V P+ +GVY     N+LG+A     L V
Sbjct: 251  DDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 296



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 61/229 (26%), Positives = 97/229 (42%), Gaps = 17/229 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP+ T  L++VE+ EG+ A F+ ++         V W H   P++         + G  +
Sbjct: 82   APLFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHS 139

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696
            L I     ED G Y   A+N  G+A        H    +Y+E     A    ++LE    
Sbjct: 140  LHIAHVGSEDEGLYAVSAVNTHGQA--------HCSAQLYVEEPRTAASGPSSKLEKMPS 191

Query: 1697 YQRHSAQDEV-ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
                  Q E+     P F  P++D+ V   + A  E ++   G P   + W  NG  I++
Sbjct: 192  IPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQV--TGLPYPTISWFHNGHRIQS 249

Query: 1756 SN--RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            S+  R+T   D     L    V P+ +G Y     N+LG+A   + L+V
Sbjct: 250  SDDRRMTQYRDVH--RLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 296



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 71/261 (27%), Positives = 110/261 (42%), Gaps = 18/261 (6%)

Query: 1805 KASLQLESQHE--SALQ--KIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQ 1860
            K  L L S HE  S +   K+   +D      R  V  ++  AP F T+L    ++ EG+
Sbjct: 42   KCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSL--APLF-TRLLEDVEVLEGR 98

Query: 1861 SAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920
            +A ++C+I   P P   V W   G  ++     R   D G  +L I  V  ED G Y   
Sbjct: 99   AARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVS 156

Query: 1921 AINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQF 1980
            A+N  GQA  S +L V+   +    S   S LEK+  + ++       Q +   +  P F
Sbjct: 157  AVNTHGQAHCSAQLYVEEPRTAA--SGPSSKLEKMPSIPEEPE-----QGELERLSIPDF 209

Query: 1981 GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDIL 2040
             +P+++ EV       LE  +T +  PT  + W+ NG  +Q     + T       L   
Sbjct: 210  LRPLQDLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQSSDDRRMTQYRDVHRLVFP 267

Query: 2041 YAYAEDTGTYMCKATNAVGEA 2061
                +  G Y     N +G+A
Sbjct: 268  AVGPQHAGVYKSVIANKLGKA 288



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 59/216 (27%), Positives = 95/216 (43%), Gaps = 10/216 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F + +++ EV EG     +  ++    P   V W   G P+++    +   D G  +L
Sbjct: 83   PLFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHSL 140

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             I +  +ED G Y   A N  G+A  ++ + V+        +    +L+K+  +   E P
Sbjct: 141  HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPR--TAASGPSSKLEKMPSIP--EEP 196

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
            +  E E+    P FL  L  LE +     A  EC+V  +  P+ TI WFHNG +I++   
Sbjct: 197  EQGELERL-SIPDFLRPLQDLE-VGLAKEAMLECQVTGL--PYPTISWFHNGHRIQSSDD 252

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
             R T       L       + +G Y     NKLG+A
Sbjct: 253  RRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKA 288



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 58/217 (26%), Positives = 89/217 (41%), Gaps = 27/217 (12%)

Query: 389 ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           +LAP F ++ +D +V EG+  RFDC+++G P P VTW      + +  N + L  + G H
Sbjct: 80  SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLR-LRQDGGLH 138

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-------------IEK---------- 485
           +L I +V   D G+    A N  G+     +L V             +EK          
Sbjct: 139 SLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQ 198

Query: 486 ---EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542
              E++  P F+     L V   +  +L  +  G P P I+W  +G  I  + + R+   
Sbjct: 199 GELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQY 258

Query: 543 GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
                L  P      A  Y+    N  G  A  A LY
Sbjct: 259 RDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLY 295



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 62/235 (26%), Positives = 105/235 (44%), Gaps = 23/235 (9%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S R+ V  P ++P    T L     V EG+ A F+C++     P   + + H G  ++ +
Sbjct: 72   SARLTVR-PSLAP--LFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEES 126

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALG--HCTSAISMTVTAKGSIISESQR 2346
                +  D G  SL I H   ED G Y+V A+N  G  HC++ + +    + +    S +
Sbjct: 127  ENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE-EPRTAASGPSSK 185

Query: 2347 PEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDP 2406
             E +  I E       +R  IP+        F +PLQ+++ +   + A  +C++  +  P
Sbjct: 186  LEKMPSIPEEPEQGELERLSIPD--------FLRPLQDLE-VGLAKEAMLECQVTGLPYP 236

Query: 2407 TLKVEWFRNEKLIE--DSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            T  + WF N   I+  D  R+T+  D     +    V  +  GVY    +N LG+
Sbjct: 237  T--ISWFHNGHRIQSSDDRRMTQYRDVH--RLVFPAVGPQHAGVYKSVIANKLGK 287



 Score = 67.3 bits (157), Expect = 1e-09
 Identities = 46/176 (26%), Positives = 78/176 (44%), Gaps = 4/176 (2%)

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY-FQMSRTADEYTLRISEAFPEDEGDYKC 4695
            G+   F C + G     V W    +L++P+    +M     +  L ++    +D G Y C
Sbjct: 1    GEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTC 60

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
                +   +T +A+L V +P  A     L  L D+ V EG+ A+F  +I+    P + W 
Sbjct: 61   KLSTAKDELTCSARLTV-RPSLAPLFTRL--LEDVEVLEGRAARFDCKISGTPPPVVTWT 117

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              G  + E+ + ++  +G    L I +   ED G +   A    GQ   SA+L V+
Sbjct: 118  HFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 173



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 37/117 (31%), Positives = 61/117 (52%), Gaps = 3/117 (2%)

Query: 49  TTQVESSGDRQPITAGRPGEPS-PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTR 107
           T ++ ++ D    +A     PS  P+F ++ ++    +G  A+F+ K+ G P PVV+WT 
Sbjct: 59  TCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTH 118

Query: 108 KKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
              P+ E    ++R  +  G  SL I  +G  DEG Y  +A N +G+A CS  +  E
Sbjct: 119 FGCPMEESE--NLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 173



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 40/135 (29%), Positives = 57/135 (42%), Gaps = 5/135 (3%)

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
           +   + L I  V+  D G +TC ARN+ G       L + E     AP+F      + V 
Sbjct: 462 DDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAE-----APRFESIMEDVEVG 516

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            GE         G P P I W KD V +  +  +    +    +L +    A D   Y C
Sbjct: 517 AGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTC 576

Query: 564 TAQNVAGSTATRARL 578
           TAQN+AG  + +A L
Sbjct: 577 TAQNLAGEVSCKAEL 591



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 62/210 (29%), Positives = 92/210 (43%), Gaps = 16/210 (7%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            +++EG++A F+ ++       +T  W   G  +  +  ++   D G  +L IA V +ED 
Sbjct: 93   EVLEGRAARFDCKISGTPPPVVT--WTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDE 150

Query: 1114 GVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEIS 1173
            G+Y V A N  G+A  SA + VE   +   +S      EK   I E    EP  Q E   
Sbjct: 151  GLYAVSAVNTHGQAHCSAQLYVEEPRT--AASGPSSKLEKMPSIPE----EP-EQGELER 203

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS--RFKTYYD 1231
             S P F++PL +   V   K   LEC++  +  PT  + WFHNG  +      R   Y D
Sbjct: 204  LSIPDFLRPLQD-LEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQSSDDRRMTQYRD 260

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSA 1261
               +    +    A  G Y     N LG A
Sbjct: 261  VHRLVFPAVGPQHA--GVYKSVIANKLGKA 288



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 14/227 (6%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F   L+ V  +EG    F+ +I   G P   + W   G  +E S         G  SL
Sbjct: 83  PLFTRLLEDVEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSL 140

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQHPETLQYIQQLEDYSK 755
            +  +  +D G Y   AV+  G A   A L+V  PR      S   E +  I        
Sbjct: 141 HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIP------- 193

Query: 756 YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
            +  E  E +    P F+RPLQDL E+   + A  E Q+T +  PT  + W+ +G  I +
Sbjct: 194 -EEPEQGELERLSIPDFLRPLQDL-EVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQS 249

Query: 816 SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           S             L    +  + AG Y     NKLG+A   A + V
Sbjct: 250 SDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 296



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 62/229 (27%), Positives = 94/229 (41%), Gaps = 18/229 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P FT    D+ + E  +A F+C++         V W H G P+     ++   D G   L
Sbjct: 83   PLFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHSL 140

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES-IQKLE 3676
             I  V   D GLY   A N HG+A  S +L V+       EP+  +   SG  S ++K+ 
Sbjct: 141  HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE-------EPRTAA---SGPSSKLEKMP 190

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
                + E+   E E+ + P F   ++D ++V        +C+V  +  PT  I WFHNG 
Sbjct: 191  SIPEEPEQ--GELERLSIPDFLRPLQD-LEVGLAKEAMLECQVTGLPYPT--ISWFHNGH 245

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               +              L    +  + AG Y     NK G A   A +
Sbjct: 246  RIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHL 294



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 1/96 (1%)

Query: 387 EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
           E A AP+F  + +D +V  G+  RF   V G+P P++ W+  D  +  + +H   V E  
Sbjct: 499 ELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWY-KDEVLLTESSHVSFVYEEN 557

Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             +L++ +    D GV TC A+N +GE + +  L V
Sbjct: 558 ECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 593



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 57/216 (26%), Positives = 92/216 (42%), Gaps = 13/216 (6%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P+FT+ L++++ + EG+ A FDC++   G P   V W      +E+S  +    D G  S
Sbjct: 83   PLFTRLLEDVE-VLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 139

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQ-PH 2494
            + I+HV  EDEG+Y   A N  G+               +  T       K++K+   P 
Sbjct: 140  LHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE-----EPRTAASGPSSKLEKMPSIPE 194

Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
            E    E +R    P F + L    E+   + A  E +V  +  P++   W+ NG  ++  
Sbjct: 195  EPEQGELER-LSIPDFLRPLQ-DLEVGLAKEAMLECQVTGLPYPTI--SWFHNGHRIQSS 250

Query: 2555 SRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
               R T       L   +V    AG+Y     N+ G
Sbjct: 251  DDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLG 286



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 63/254 (24%), Positives = 102/254 (40%), Gaps = 18/254 (7%)

Query: 3396 KLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVE 3455
            KL T +D +      +V      AP+FT  L ++E L EG  A F+ +++ T  P   V 
Sbjct: 61   KLSTAKDELTCSARLTVRPSL--APLFTRLLEDVEVL-EGRAARFDCKISGTPPP--VVT 115

Query: 3456 WYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            W   G  ++     R   D G   L I+    ED G Y   A N +G+A  +A + V+  
Sbjct: 116  WTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEP 175

Query: 3516 RNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSA 3575
            R          G    ++K+ ++       +    E E  + P+F     DL +     A
Sbjct: 176  RT------AASGPSSKLEKMPSI-----PEEPEQGELERLSIPDFLRPLQDLEVGLAKEA 224

Query: 3576 HFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKAT 3635
              EC++  +   +  + WFHNG  + +    +         L    V  + AG+Y     
Sbjct: 225  MLECQVTGLPYPT--ISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIA 282

Query: 3636 NRHGEATVSCKLQV 3649
            N+ G+A     L V
Sbjct: 283  NKLGKAACYAHLYV 296



 Score = 58.4 bits (135), Expect = 6e-07
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P FE I ++     G  A+F   + G P P + W + +  L E +  S  Y E   + SL
Sbjct: 504 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEE--NECSL 561

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAIC 157
           ++   G  D G YTCTA+N  GE  C
Sbjct: 562 VVLSTGAQDGGVYTCTAQNLAGEVSC 587



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 60/246 (24%), Positives = 100/246 (40%), Gaps = 21/246 (8%)

Query: 3641 ATVSCKLQVKGRQGIILEPQLPSHFKSG--TESIQKLEETLHKREEITIEDEKPNPPRFT 3698
            A + CK+   GR+  +L   +     SG  T  +   ++ L     +T+       P FT
Sbjct: 30   ALLKCKMHFDGRKCKLLLTSVHED-DSGVYTCKLSTAKDELTCSARLTVRPSLA--PLFT 86

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDID 3758
              ++D ++V EG    FDC++   G P   + W H G P      +    D G  +L I 
Sbjct: 87   RLLED-VEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIA 143

Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISD 3818
            ++ + D G Y   A N  G A  +A++     R            SG   K  +   I +
Sbjct: 144  HVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPR---------TAASGPSSKLEKMPSIPE 194

Query: 3819 APKEEPIVS-TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG-KLLPSGH 3876
             P++  +   + P F+  ++   V  ++    EC+V     P   I W+ NG ++  S  
Sbjct: 195  EPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYP--TISWFHNGHRIQSSDD 252

Query: 3877 RYRTVY 3882
            R  T Y
Sbjct: 253  RRMTQY 258



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 61/225 (27%), Positives = 98/225 (43%), Gaps = 16/225 (7%)

Query: 913  TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIK 972
            T + + + + EG  A F+ ++   G     V W   G P+E S  +    + G  +L I 
Sbjct: 86   TRLLEDVEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIA 143

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKR 1032
             V   D G Y   A N  GQA  SA L +  ++   A S     LEK+  + +     + 
Sbjct: 144  HVGSEDEGLYAVSAVNTHGQAHCSAQLYV--EEPRTAASGPSSKLEKMPSIPE-----EP 196

Query: 1033 TEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSAN-- 1090
             + E++    P FL PL+   ++   + A  E +V        T+ W+ NG +I S++  
Sbjct: 197  EQGELERLSIPDFLRPLQDL-EVGLAKEAMLECQVTGLP--YPTISWFHNGHRIQSSDDR 253

Query: 1091 RIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            R+  Y D     L   +V  + +GVY  V  N  G+A   A + V
Sbjct: 254  RMTQYRDVH--RLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 296



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 62/237 (26%), Positives = 102/237 (43%), Gaps = 22/237 (9%)

Query: 767  SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG 826
            S  P F R L+D+ E+ EGR A F+ +++    P   V W   G P+  S  +    + G
Sbjct: 80   SLAPLFTRLLEDV-EVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGG 136

Query: 827  YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXX 886
              SL+I H+ +ED G Y V AVN  G+A  +A + V    T  +    P  +  +EK   
Sbjct: 137  LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASG---PSSK--LEKMPS 191

Query: 887  XXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWL 946
                             E    P+F  P++D + +     A  E ++  +   T  + W 
Sbjct: 192  IPEEPEQGEL-------ERLSIPDFLRPLQD-LEVGLAKEAMLECQVTGLPYPT--ISWF 241

Query: 947  KDGRPVEASS--RITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +G  +++S   R+T + +     L   +V    AG Y     N +G+A   A+L +
Sbjct: 242  HNGHRIQSSDDRRMTQYRDVH--RLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYV 296



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 57/231 (24%), Positives = 88/231 (38%), Gaps = 18/231 (7%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            +F   L ++   EG    F+C +  +  P   + W     P+      +   D    SL 
Sbjct: 84   LFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGLHSLH 141

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQ-AEEA 2893
            I H   ED G+Y   A N+ G A  S  L     +        P  K  LE +    EE 
Sbjct: 142  IAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTA---ASGPSSK--LEKMPSIPEEP 196

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
               +  R S+PD   P  +  + +A E  ++E QV  L         P   I W+ NG  
Sbjct: 197  EQGELERLSIPDFLRPLQDLEVGLAKE-AMLECQVTGL---------PYPTISWFHNGHR 246

Query: 2954 LEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCT 3004
            ++     ++T       L    V  + +G+Y     NK G+A   + +Y T
Sbjct: 247  IQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVT 297



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 54/225 (24%), Positives = 91/225 (40%), Gaps = 15/225 (6%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            +++EG+    + ++     P   + W   G  +E+    +L  D G  +L +  V   D 
Sbjct: 93   EVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDE 150

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD 3041
            G+Y   A N  G+A  S+ +Y         RT     +  LEK+     S+ +EP +Q +
Sbjct: 151  GLYAVSAVNTHGQAHCSAQLYVEE-----PRTAASGPSSKLEKM----PSIPEEP-EQGE 200

Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY 3101
             +    P+F    +D+ ++   + A  E  +  TG     I WF+NG  I++S   R   
Sbjct: 201  LERLSIPDFLRPLQDL-EVGLAKEAMLECQV--TGLPYPTISWFHNGHRIQSSDDRRMTQ 257

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKG 3146
               +  L         +G Y     NK G+A     L   D   G
Sbjct: 258  YRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPG 302



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 3/116 (2%)

Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           S+  + ++ P+F   ++D+ E+  G  A F   +     P   + WYKD   +T SS ++
Sbjct: 495 SVTLELAEAPRFESIMEDV-EVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVS 551

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPE 876
            ++     SL ++   A+D G YT  A N  GE    A + V +  T     G+ E
Sbjct: 552 FVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGE 607



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 49/221 (22%), Positives = 88/221 (39%), Gaps = 12/221 (5%)

Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG 1500
            ++ P F    + +E V+EG+   F+CK+         V W   G P+      R   D G
Sbjct: 80   SLAPLFTRLLEDVE-VLEGRAARFDCKISGTPPP--VVTWTHFGCPMEESENLRLRQDGG 136

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLED 1560
              +L I  + +ED G+Y   AVN  G    S +L             ++  LE++  + +
Sbjct: 137  LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSK--LEKMPSIPE 194

Query: 1561 RSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPL 1620
              +    + +       P     L+++E+   + A  E ++  +   T  + W+HN   +
Sbjct: 195  EPEQGELERL-----SIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRI 247

Query: 1621 KSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            +S      T       L   +  P+ +G Y     N LG+A
Sbjct: 248  QSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKA 288



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 44/178 (24%), Positives = 76/178 (42%), Gaps = 12/178 (6%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F+R L ++E +EG     +C++   G     V W   G P++     R   +    +
Sbjct: 82   APLFTRLLEDVEVLEGRAARFDCKIS--GTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 139

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSR 1429
            L +  V  ED G+Y   A N  G+A   C+ ++  ++     S   S LEK+  + +   
Sbjct: 140  LHIAHVGSEDEGLYAVSAVNTHGQA--HCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPE 197

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
              +     E ++I P F+ RP     V   +    EC++  +      + WF NG  +
Sbjct: 198  QGEL----ERLSI-PDFL-RPLQDLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRI 247



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 43/166 (25%), Positives = 69/166 (41%), Gaps = 9/166 (5%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I      D G  +C A N+ G    SV LE  +      PRF + ++++E +  G++A
Sbjct: 468  LRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-----PRFESIMEDVE-VGAGETA 521

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             F   V     PD  I WY +   +  S+ +  V +     L +  T   D G Y C A 
Sbjct: 522  RFAVVVEGKPLPD--IMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQ 579

Query: 3228 NKYGEDFTRATINCY-GKGGVYLESLQPDSLAKIRELESLQGAQQQ 3272
            N  GE   +A +  +  +  + +E +  D   + R L       Q+
Sbjct: 580  NLAGEVSCKAELAVHSAQTAMEVEGVGEDEDHRGRRLSDFYDIHQE 625



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 24/86 (27%), Positives = 47/86 (54%), Gaps = 3/86 (3%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            + P F   +++++ +  G+TA F   ++  G P   + W+++E L+ +SS ++  ++   
Sbjct: 502  EAPRFESIMEDVE-VGAGETARF--AVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE 558

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             S+ +     +D GVY C A NL GE
Sbjct: 559  CSLVVLSTGAQDGGVYTCTAQNLAGE 584



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 3/121 (2%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + +AP F   M+D+ V   + A F   ++  G P   + W ++ V +  S+ ++ +++  
Sbjct: 500  LAEAPRFESIMEDVEVGAGETARFA--VVVEGKPLPDIMWYKDEVLLTESSHVSFVYEEN 557

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-KASLQLESQHESALQKIQQLE 1825
              +L +     +D G YTC A N  GE    + L V S + ++++E   E    + ++L 
Sbjct: 558  ECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDEDHRGRRLS 617

Query: 1826 D 1826
            D
Sbjct: 618  D 618



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 3/116 (2%)

Query: 3552 AESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN- 3610
            +ES  PP F     D +L E  +A   C  +P    +  + W  + K L +   V  ++ 
Sbjct: 1597 SESDFPPVFHIKLKDQVLLEGEAATLLC--LPAACPAPHISWMKDKKSLRSEPSVIIVSC 1654

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
              G  +L I    +R AGLY C ATN  G  T SC + V    G +  P++   ++
Sbjct: 1655 KDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVTQTYQ 1710



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 53/212 (25%), Positives = 83/212 (39%), Gaps = 14/212 (6%)

Query: 3949 TIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
            T K  T++  LT      V     P F T++     ++E    +F+C+++  G P   V 
Sbjct: 59   TCKLSTAKDELTCSARLTVRPSLAPLF-TRLLEDVEVLEGRAARFDCKIS--GTPPPVVT 115

Query: 4009 WFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
            W   G P+          D G  +++   V  ED G Y   A N +G     A +    +
Sbjct: 116  WTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE-E 174

Query: 4069 PGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWA 4128
            P         K    +EK+  +       PEQ  E  +   P     L D + V   + A
Sbjct: 175  PRTAASGPSSK----LEKMPSIPEE----PEQG-ELERLSIPDFLRPLQD-LEVGLAKEA 224

Query: 4129 RFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
               C+VTG P P + W  NG+ I +    ++T
Sbjct: 225  MLECQVTGLPYPTISWFHNGHRIQSSDDRRMT 256



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 267 KIAQKPRNSKLQE------GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
           ++A+ PR   + E      G  A+F V + G P P + W+K+   L  S+    +   N 
Sbjct: 499 ELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE 558

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            +L V +T   D G YT  A+N  G +     LAV S
Sbjct: 559 CSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHS 595



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 1/90 (1%)

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT- 541
            +  E    P F  +     + EGE   L       P P I+W KD   +   P + I + 
Sbjct: 1595 VRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSC 1654

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              G   L IPRA    A  Y+C+A NV GS
Sbjct: 1655 KDGRQLLSIPRAGKRHAGLYECSATNVLGS 1684



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096
            +++ + PRF   ++   ++  G++A F   VE +      + WY +   +T ++ +   +
Sbjct: 498  LELAEAPRFESIMEDV-EVGAGETARFAVVVEGKP--LPDIMWYKDEVLLTESSHVSFVY 554

Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
            +    +L + S  A+D GVYT  A+N AGE    A + V +
Sbjct: 555  EENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHS 595



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 51/231 (22%), Positives = 87/231 (37%), Gaps = 20/231 (8%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP+FT  L+  + L EG+    + ++     P   + W   G  +     L+   D GL 
Sbjct: 82   APLFTRLLEDVEVL-EGRAARFDCKISGTPPP--VVTWTHFGCPMEESENLRLRQDGGLH 138

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXX 2760
            +L I  + ++D G+Y   A N  G+A  +A + +E+       S     L+++ ++    
Sbjct: 139  SLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPR--TAASGPSSKLEKMPSIPEEP 196

Query: 2761 XXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSG- 2819
                           F+  L ++          EC V     PT  I WF N   + S  
Sbjct: 197  EQGELERLSIPD---FLRPLQDLEVGLAKEAMLECQVTGLPYPT--ISWFHNGHRIQSSD 251

Query: 2820 ----TRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
                T+Y+  H   + ++   H     +G+Y     N  G A     L  T
Sbjct: 252  DRRMTQYRDVHRLVFPAVGPQH-----AGVYKSVIANKLGKAACYAHLYVT 297



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+F + ++   V   E  RF   VE K  P   I WY++  LL        VY+    SL
Sbjct: 504  PRFESIMEDVEVGAGETARFAVVVEGKPLPD--IMWYKDEVLLTESSHVSFVYEENECSL 561

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
             +L   A+D G Y C A N  GE   KA ++
Sbjct: 562  VVLSTGAQDGGVYTCTAQNLAGEVSCKAELA 592



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/92 (31%), Positives = 40/92 (43%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F   ++ V    G    F   +E  G P   I W K+   +  SS  + ++     SL
Sbjct: 504 PRFESIMEDVEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVSFVYEENECSL 561

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +LS   QD G YTC A +  G    KA L V
Sbjct: 562 VVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 593



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 3/77 (3%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            G+   FEC V    D  ++++W    + L P+  + K   D     L +T  +E+DSG+Y
Sbjct: 1    GEMALFECLVAGPTD--VEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVY 58

Query: 2847 TCKATNSKGSATTSGSL 2863
            TCK + +K   T S  L
Sbjct: 59   TCKLSTAKDELTCSARL 75



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 56/231 (24%), Positives = 88/231 (38%), Gaps = 26/231 (11%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            S  P F   ++   V E    RF+C++     P   + W   G  +      R   D G 
Sbjct: 80   SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPV--VTWTHFGCPMEESENLRLRQDGGL 137

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQM 3946
             SL I +V +ED G Y   AVN  G+    A +  ++          PR      A +  
Sbjct: 138  HSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEE----------PR-----TAASGP 182

Query: 3947 EATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMK 4006
             + ++K  S     E +  ++++   P F+  +Q     +  E    ECQ+   G P   
Sbjct: 183  SSKLEKMPS--IPEEPEQGELERLSIPDFLRPLQDLEVGLAKE-AMLECQV--TGLPYPT 237

Query: 4007 VEWFFNGKPLLHKN--RFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            + WF NG  +   +  R T   D   +   F  V P+ +G Y     N  G
Sbjct: 238  ISWFHNGHRIQSSDDRRMTQYRDVHRLV--FPAVGPQHAGVYKSVIANKLG 286



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 3/98 (3%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN 963
            E  + P F++ ++D + +  G  A F   +E  G     + W KD   +  SS ++  + 
Sbjct: 499  ELAEAPRFESIMED-VEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVSFVYE 555

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                +L + S    D G YTC A N  G+ +  A L +
Sbjct: 556  ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 593



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 3/95 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP F + ++  + +  G+       VE +  P+  I W+K+ V LT  + +   ++   
Sbjct: 502  EAPRFESIMEDVE-VGAGETARFAVVVEGKPLPD--IMWYKDEVLLTESSHVSFVYEENE 558

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +L + S    D G+YTC A NL GE    A + +
Sbjct: 559  CSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 593



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 1/94 (1%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTL 4680
            PP     LKD+++ EG+A    C     P P + W K  K ++      +    D    L
Sbjct: 1602 PPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLL 1661

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
             I  A     G Y+C A N  G +T +  + V +
Sbjct: 1662 SIPRAGKRHAGLYECSATNVLGSITSSCTVAVAR 1695



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 21/56 (37%), Positives = 28/56 (50%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH 4166
            P+F  L + V V EG  ARF C+++G P P V W   G  +      +L  DG  H
Sbjct: 83   PLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLH 138



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/116 (23%), Positives = 45/116 (38%)

Query: 376  QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            Q E   +   SE    P F    +D+ + EG+     C     P P ++W  + + +R +
Sbjct: 1587 QEELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSE 1646

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
             +  I+  + G   L I       +G+  C A N  G     C + V      +AP
Sbjct: 1647 PSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAP 1702



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 5/92 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F ++ +D V++  G+ A +  +++  G     I W+ +   +  S  +  VY      
Sbjct: 504  PRFESIMED-VEVGAGETARF--AVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECS 560

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
            L +L T   D G Y+C A N  G  E+S K E
Sbjct: 561  LVVLSTGAQDGGVYTCTAQNLAG--EVSCKAE 590



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 14/130 (10%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLE--PVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            PRF +  + +E V  G+   F   +E  P+ D    + W+K+   +T       +++   
Sbjct: 504  PRFESIMEDVE-VGAGETARFAVVVEGKPLPD----IMWYKDEVLLTESSHVSFVYEENE 558

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDR 1561
             +L ++   A+D G+YTC A NL G  EVSC+         V S Q    +E +   ED 
Sbjct: 559  CSLVVLSTGAQDGGVYTCTAQNLAG--EVSCKAEL-----AVHSAQTAMEVEGVGEDEDH 611

Query: 1562 SKYHRTDMVD 1571
                 +D  D
Sbjct: 612  RGRRLSDFYD 621



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 2/99 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            +AP   + +++VE+  G+ A F   ++        + WY +   L   S  +        
Sbjct: 502  EAPRFESIMEDVEVGAGETARFA--VVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENEC 559

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674
            +L ++S   +D G YTC A N  GE        VHS ++
Sbjct: 560  SLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQT 598



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 3/106 (2%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V + + +APRF + +    ++  G++A +   +E  P P+  + WY +  +L        
Sbjct: 496  VTLELAEAPRFESIMED-VEVGAGETARFAVVVEGKPLPD--IMWYKDEVLLTESSHVSF 552

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
              +    +L +L+   +D G YTC A N  G+      L V S ++
Sbjct: 553  VYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQT 598



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + + +AP+F   + ++E   G        ++  G     + W+ +   +         YE
Sbjct: 498  LELAEAPRFESIMEDVEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVSFVYE 555

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +  +L +LS   +D GVYTC A N  GE      L V
Sbjct: 556  ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 593



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA-RLKSTFDFGLVTLSINSLRNDDSGIY 2715
            G+    E  V   TD  ++++W   G  L     + K  FD     L + S+  DDSG+Y
Sbjct: 1    GEMALFECLVAGPTD--VEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVY 58

Query: 2716 TCKATNLLGEAVSTASIKI 2734
            TCK +    E   +A + +
Sbjct: 59   TCKLSTAKDELTCSARLTV 77



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 1/66 (1%)

Query: 1338 GDQTMRVEWFCNGKPIKTGH-RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
            G   + V+W C G+ ++    + +  ++     L L SV+ +DSGVYTC+ +    E   
Sbjct: 12   GPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTC 71

Query: 1397 SCALRV 1402
            S  L V
Sbjct: 72   SARLTV 77



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%)

Query: 2942 DLKIEWYFNGKVLEQGS-RFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            D++++W   G++L+    + K+  D     L L  V+E DSG+YTCK    + E   S+
Sbjct: 15   DVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSA 73



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 924  GGFAHFEARLEPIGDSTLRVEWLKDGRPVE-ASSRITTFFNFGYVALTIKSVTVHDAGHY 982
            G  A FE  +   G + + V+WL  GR ++ A  +    F+     L + SV   D+G Y
Sbjct: 1    GEMALFECLVA--GPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVY 58

Query: 983  TCRAYNAIGQATTSANLTI 1001
            TC+   A  + T SA LT+
Sbjct: 59   TCKLSTAKDELTCSARLTV 77



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 8/117 (6%)

Query: 2621 LKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDK-LVEGQHVYLEAQVEPRTDPNLKIEWF 2679
            L  +   ++   +V +     P+F  H+K  D+ L+EG+   L     P   P   I W 
Sbjct: 1582 LSASVQEELGHQYVRSESDFPPVF--HIKLKDQVLLEGEAATLLCL--PAACPAPHISWM 1637

Query: 2680 KNGVTLTT--GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            K+  +L +     + S  D G   LSI       +G+Y C ATN+LG   S+ ++ +
Sbjct: 1638 KDKKSLRSEPSVIIVSCKD-GRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 1693



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746
            +  E   PP F +++KD + + EG      C   P   P   I W  + +   +   V  
Sbjct: 1595 VRSESDFPPVFHIKLKDQV-LLEGEAATLLCL--PAACPAPHISWMKDKKSLRSEPSVII 1651

Query: 3747 LN-DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            ++   G   L I     R AG Y C ATN  GS T++  +
Sbjct: 1652 VSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTV 1691



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 3/106 (2%)

Query: 3680 HKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA 3739
            H  +  ++  E    PRF   I ++++V  G    F   VE  G P   I W+ +     
Sbjct: 489  HGTQTCSVTLELAEAPRFE-SIMEDVEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLT 545

Query: 3740 TGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
              S V  + +    +L +    A+D G YTC A N  G  +  A++
Sbjct: 546  ESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAEL 591



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/110 (21%), Positives = 46/110 (41%), Gaps = 3/110 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            + E P+F   +++ EV  G        +     P   + WY +   + +       Y+  
Sbjct: 500  LAEAPRFESIMEDVEVGAGETARFAVVVE--GKPLPDIMWYKDEVLLTESSHVSFVYEEN 557

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDE 2082
              +L +L   A+D G Y C A N  GE    + + V  A++ + ++ + E
Sbjct: 558  ECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGE 607



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/52 (34%), Positives = 24/52 (46%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P F S+ + V V  GE ARF   V G P P +MW  +   +   S     Y+
Sbjct: 504  PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYE 555



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI--EASNRLTTMHDFGYV 1768
            PVF + +KD  + E +AA      +P   P   + W+++   +  E S  + +  D G  
Sbjct: 1603 PVFHIKLKDQVLLEGEAATLLC--LPAACPAPHISWMKDKKSLRSEPSVIIVSCKD-GRQ 1659

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             L++       +G Y C A N LG   +S T+ V
Sbjct: 1660 LLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 1693



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 3/70 (4%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH-DFGYVSMTISHVRDEDEGVY 2449
            G+ A F+C  +  G   ++V+W    +L++ +    K H D     + ++ V ++D GVY
Sbjct: 1    GEMALFEC--LVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVY 58

Query: 2450 MCRASNLLGE 2459
             C+ S    E
Sbjct: 59   TCKLSTAKDE 68



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 10/106 (9%)

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            T +   E    P F +   D+ +    +A F   ++        + W+ +   L   S V
Sbjct: 493  TCSVTLELAEAPRFESIMEDVEVGAGETARFA--VVVEGKPLPDIMWYKDEVLLTESSHV 550

Query: 3607 KTI---NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              +   N+   V+L  G    +D G+YTC A N  GE  VSCK ++
Sbjct: 551  SFVYEENECSLVVLSTGA---QDGGVYTCTAQNLAGE--VSCKAEL 591



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F S + ++    G+   F   VE    P   I W+ +   L   +     ++ +  SL +
Sbjct: 506  FESIMEDVEVGAGETARFAVVVEGK--PLPDIMWYKDEVLLTESSHVSFVYEENECSLVV 563

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
              T  +D G+YTC A N  G  +    L
Sbjct: 564  LSTGAQDGGVYTCTAQNLAGEVSCKAEL 591



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 2926 GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYT 2985
            G+       VE K  PD  I WY +  +L + S      +    +L ++    +D G+YT
Sbjct: 518  GETARFAVVVEGKPLPD--IMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYT 575

Query: 2986 CKAYNKRGEAFTSSTVYCTSKDNLIE 3011
            C A N  GE    + +   S    +E
Sbjct: 576  CTAQNLAGEVSCKAELAVHSAQTAME 601



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH-DFGYV 2167
            PVF   L   + L EG+ A   C       PH  I W  + + +R+           G  
Sbjct: 1603 PVFHIKLKD-QVLLEGEAATLLCLPAACPAPH--ISWMKDKKSLRSEPSVIIVSCKDGRQ 1659

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
             L I       +G Y C ATN LG   ++CT+ VA
Sbjct: 1660 LLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVA 1694



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)

Query: 3575 AHFECRLIPVNDSSMRVEWFHNGKPLLTGS-RVKTINDFGFVILEIGGVYQRDAGLYTCK 3633
            A FEC +    D  + V+W   G+ L     + K   D     L +  V++ D+G+YTCK
Sbjct: 4    ALFECLVAGPTD--VEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCK 61

Query: 3634 ATNRHGEATVSCKLQVK 3650
             +    E T S +L V+
Sbjct: 62   LSTAKDELTCSARLTVR 78


>AK128020-1|BAC87234.1|  595|Homo sapiens ursor.  protein.
          Length = 595

 Score =  102 bits (245), Expect = 3e-20
 Identities = 95/354 (26%), Positives = 147/354 (41%), Gaps = 40/354 (11%)

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
            +L    V  ED A +   A N  G  +  A L+V         G  PP    +A  V V 
Sbjct: 109  VLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVT--------GHAPPQIASSAPTVRVL 160

Query: 4527 SGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             GQ V L   V   +P+ + +WLK+G+ + P  R+ I   DG+  L +  A  + +G+Y 
Sbjct: 161  EGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSI-RADGS--LHLDRALQEHAGRYS 217

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N+AG    D E VV +                PP I       I  EG      C 
Sbjct: 218  CVATNTAGSQHRDVELVVQV----------------PPRIHPTATHHITNEGVPASLPCV 261

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
              G P PT+ W K  + L     ++ +S+   E TL I++   +D G Y C A N+ G  
Sbjct: 262  ASGVPAPTITWTKETNALTSRGPHYNVSK---EGTLLIAQPSAQDAGAYVCTATNTVGFS 318

Query: 4705 TVAAKLKV-TQP--DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            +   +L V T+P      +  A  PL+ +    G+      +      P + W ++   +
Sbjct: 319  SQEMRLSVNTKPRIHMNGSRNADVPLQ-VTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPV 377

Query: 4762 PE-TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            P  T  + ++  G+   L +      D+G + C A+  AG       L V+ +T
Sbjct: 378  PPITNRYGLLPSGS---LRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQGRT 428



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 84/306 (27%), Positives = 124/306 (40%), Gaps = 31/306 (10%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK-NGKKVQPDI---RNKILEEDGTY 4569
            P  T   ++V V  G+   L  + TG  P  V W + +G+ +   +   R     +  + 
Sbjct: 49   PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG 108

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
             L      P+D   Y C A N  G+ + +A  +V+               +APP+I    
Sbjct: 109  VLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVT--------------GHAPPQIASSA 154

Query: 4630 KDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
                V EGQ +   C ++ G+PLP   W K  + + P    + S  AD  +L +  A  E
Sbjct: 155  PTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGS--RHSIRADG-SLHLDRALQE 211

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
              G Y CVA N+AG      +L V  P +    P  T     +  EG PA      +   
Sbjct: 212  HAGRYSCVATNTAGSQHRDVELVVQVPPRIH--PTAT---HHITNEGVPASLPCVASGVP 266

Query: 4749 KPTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             PTI W +E  AL    P + +  EG    LLI     +D G + C AT   G      +
Sbjct: 267  APTITWTKETNALTSRGPHYNVSKEG---TLLIAQPSAQDAGAYVCTATNTVGFSSQEMR 323

Query: 4808 LVVKSK 4813
            L V +K
Sbjct: 324  LSVNTK 329



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 61/185 (32%), Positives = 78/185 (42%), Gaps = 10/185 (5%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ---IRDDYNHKILVNESGN 447
           APQ  ++ +D  V  G+     CR TGRP P VTW   D Q   +R          +  +
Sbjct: 48  APQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDS 107

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
             L   +V   D     C ARN  G+   + RL V        P+      T+ V EG+P
Sbjct: 108 GVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGH---APPQIASSAPTVRVLEGQP 164

Query: 508 VVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
           V L    + G P P   W KDG P+ P     I  DG   +L + RA    A  Y C A 
Sbjct: 165 VSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADG---SLHLDRALQEHAGRYSCVAT 221

Query: 567 NVAGS 571
           N AGS
Sbjct: 222 NTAGS 226



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 72/260 (27%), Positives = 110/260 (42%), Gaps = 35/260 (13%)

Query: 4562 ILEEDGTYT--LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            IL  +G+ +  L I  A  +D+G Y C A+N  G+A  + +  V                
Sbjct: 2    ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVG--------------- 46

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD----KLIKPSKYFQMSRTA 4675
               P++ E  +D  V  G++   +C+  G+P PTV W +GD     L   +     SR  
Sbjct: 47   -HAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQP 105

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT---QPDQADNLPALTPLRDIVV 4732
            D   L      PED+  Y C A N  G+V   A+L VT    P  A + P       + V
Sbjct: 106  DSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPT------VRV 159

Query: 4733 YEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             EGQP       +  +  P   WL++G  +P      +  +G+   L +    +E  G +
Sbjct: 160  LEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGS---LHLDRALQEHAGRY 216

Query: 4792 TCRATTAAGQVETSAKLVVK 4811
            +C AT  AG      +LVV+
Sbjct: 217  SCVATNTAGSQHRDVELVVQ 236



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 76/315 (24%), Positives = 123/315 (39%), Gaps = 44/315 (13%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           +PP+IA      ++ EG       + L+G P P   W K+G+ L   ++H I       +
Sbjct: 146 APPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSI---RADGS 202

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
           L +    +  +G Y+        C+ T+                       +Q R+ E  
Sbjct: 203 LHLDRALQEHAGRYS--------CVATN--------------------TAGSQHRDVELV 234

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
           +++      P+           EG      C  +G P P +TW      +     H    
Sbjct: 235 VQVP-----PRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPH---Y 286

Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
           N S    L+I   +  D+G   C A N  G ++ + RL+V  K ++           L V
Sbjct: 287 NVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVPLQV 346

Query: 503 --REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             + GE V L+  A G+P P +TW KD  P+ P          G  +L + + +  D+  
Sbjct: 347 TAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSG--SLRLAQVQVGDSGH 404

Query: 561 YQCTAQNVAGSTATR 575
           Y+CTA N AGS + R
Sbjct: 405 YECTASNPAGSASHR 419



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 76/318 (23%), Positives = 119/318 (37%), Gaps = 30/318 (9%)

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFE-VEFDGEPLPLIKW 4444
            E   +  K Q + R++   V    PP         RV E +      +   G PLP   W
Sbjct: 126  EARNVFGKVQAEARLI---VTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHW 182

Query: 4445 YRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR 4504
             ++  P+   P    H+      L + +   E +  ++ VA N  G+      LVV+   
Sbjct: 183  LKDGRPL---PPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ--- 236

Query: 4505 RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE 4564
                   VPP    TA +     G    L    +G     + W K    +     +  + 
Sbjct: 237  -------VPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVS 289

Query: 4565 EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPE 4624
            ++GT  LLI +   QD+G Y C A N+ G +  +    V+      KP+      N    
Sbjct: 290  KEGT--LLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVN-----TKPRIH---MNGSRN 339

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
               PL+    A G+ +   C+  G P P V W K  + + P             +LR+++
Sbjct: 340  ADVPLQVTAKA-GEEVTLDCEAKGSPPPLVTWTKDSRPVPP--ITNRYGLLPSGSLRLAQ 396

Query: 4685 AFPEDEGDYKCVAYNSAG 4702
                D G Y+C A N AG
Sbjct: 397  VQVGDSGHYECTASNPAG 414



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 48/161 (29%), Positives = 66/161 (40%), Gaps = 9/161 (5%)

Query: 4436 GEPLPLIKWYRE-NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            G P P I W +E N      P + +   S +  L+I Q   +D+  +   A N  G +  
Sbjct: 264  GVPAPTITWTKETNALTSRGPHYNV---SKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQ 320

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
               L V  K R    G       L    V   +G+ V LD +  G+ P  V W K+ + V
Sbjct: 321  EMRLSVNTKPRIHMNGSRNADVPL---QVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPV 377

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
             P      L   G+  L + +    DSG YEC A N AG A
Sbjct: 378  PPITNRYGLLPSGS--LRLAQVQVGDSGHYECTASNPAGSA 416



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 89/414 (21%), Positives = 140/414 (33%), Gaps = 41/414 (9%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKA-PL-VECNKYSMRYNEQTGDV 129
           P   ++ ++     G +A    +  G P P V+W R    PL +         + Q    
Sbjct: 49  PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG 108

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
            L  + + P D+  Y C ARN +G+      +   G                  + V   
Sbjct: 109 VLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLP 168

Query: 190 AYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES 248
                G    +    +       G+ HS   D  +     R L+E + R S        S
Sbjct: 169 CIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLD--RALQEHAGRYSCVATNTAGS 226

Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
             +     D  L    PP+I     +    EG  A      SG P P +TW K    L +
Sbjct: 227 QHR-----DVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTS 281

Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
              H  ++     TL +      D+G Y   A N  G       L+V +    ++   R+
Sbjct: 282 RGPHYNVSKEG--TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRN 339

Query: 369 QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
             +           ++++ KA                G+    DC   G P P VTW  +
Sbjct: 340 ADVP----------LQVTAKA----------------GEEVTLDCEAKGSPPPLVTWTKD 373

Query: 429 DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            R +    N   L+  SG+  L +  V + DSG   C A N +G  + +  L V
Sbjct: 374 SRPVPPITNRYGLL-PSGS--LRLAQVQVGDSGHYECTASNPAGSASHRYVLGV 424



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 43/142 (30%), Positives = 61/142 (42%), Gaps = 17/142 (11%)

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
           S +  L I      D+G  TC A N+ G+ + + +L V       AP+  E    + V  
Sbjct: 8   SSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGH-----APQLTELPRDVTVEL 62

Query: 505 GEPVVLNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGAST-------LDIPRAKAS 556
           G   +L  RA G P P +TW++ DG P+     LR+    G+ +       L        
Sbjct: 63  GRSALLACRATGRPPPTVTWRRGDGQPL----GLRLGAGRGSRSRQPDSGVLFFESVAPE 118

Query: 557 DAAWYQCTAQNVAGSTATRARL 578
           D A Y C A+NV G     ARL
Sbjct: 119 DQAPYVCEARNVFGKVQAEARL 140



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 56/267 (20%), Positives = 99/267 (37%), Gaps = 12/267 (4%)

Query: 95  LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
           L G P P   W +   PL   +++S+R      D SL + +      G Y+C A N  G 
Sbjct: 172 LAGRPLPERHWLKDGRPLPPGSRHSIR-----ADGSLHLDRALQEHAGRYSCVATNTAGS 226

Query: 155 AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
               V +  +                 V  ++   A G    T   +++T   A T+   
Sbjct: 227 QHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETN--ALTSRGP 284

Query: 215 HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEID-RSLGPVSPPKIAQKPR 273
           H +              ++           VG S  ++   ++ +    ++  + A  P 
Sbjct: 285 HYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVPL 344

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSD 332
               + G +     +  G+P P VTW K+ + +   +N++ ++ + +   LR+   Q  D
Sbjct: 345 QVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGS---LRLAQVQVGD 401

Query: 333 SGHYTLLAENPNGCIVTSGYLAVESPT 359
           SGHY   A NP G       L V+  T
Sbjct: 402 SGHYECTASNPAGSASHRYVLGVQGRT 428



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/74 (39%), Positives = 36/74 (48%), Gaps = 4/74 (5%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            + V EG PV   C V   G P     W  +GRP   GSR H++   G  +L +D      
Sbjct: 157  VRVLEGQPVSLPCIVL-AGRPLPERHWLKDGRPLPPGSR-HSIRADG--SLHLDRALQEH 212

Query: 3765 AGEYTCRATNKWGS 3778
            AG Y+C ATN  GS
Sbjct: 213  AGRYSCVATNTAGS 226



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 3245 GGVYLESLQPDSLAK-IRELESLQG-AQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
            G ++ ES+ P+  A  + E  ++ G  Q +     +   P  I       +++EGQ    
Sbjct: 108  GVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSL 167

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
               +V    P  +  W  +G+ LP G R+    D G + LD     +E++G Y CVATN 
Sbjct: 168  PC-IVLAGRPLPERHWLKDGRPLPPGSRHSIRAD-GSLHLD--RALQEHAGRYSCVATNT 223

Query: 3363 LG 3364
             G
Sbjct: 224  AG 225



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG  +   C V   R P  +  W  + +PLP G+R+    D S   L +    +E +G Y
Sbjct: 161  EGQPVSLPCIVLAGR-PLPERHWLKDGRPLPPGSRHSIRADGS---LHLDRALQEHAGRY 216

Query: 2847 TCKATNSKGS 2856
            +C ATN+ GS
Sbjct: 217  SCVATNTAGS 226



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/82 (34%), Positives = 32/82 (39%), Gaps = 4/82 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            PQ         V EG PV L   +     P     W  +GRP+  G R     D G + L
Sbjct: 148  PQIASSAPTVRVLEGQPVSLPCIVL-AGRPLPERHWLKDGRPLPPGSRHSIRAD-GSLHL 205

Query: 2038 DILYAYAEDTGTYMCKATNAVG 2059
            D   A  E  G Y C ATN  G
Sbjct: 206  D--RALQEHAGRYSCVATNTAG 225



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 1/60 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRV-TGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFD 4168
            PP   S    V V EG+     C V  G P P   WL +G  +  GSR+ +  DG  H D
Sbjct: 147  PPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLD 206



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 7/142 (4%)

Query: 1802 VQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQS 1861
            +++  SL L+   +    +   +  ++   +  DVE+ V   PR           +EG  
Sbjct: 197  IRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHIT-NEGVP 255

Query: 1862 AHYECRIEPYPDPNMRVEWYFNGKVLQS-GHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920
            A   C     P P   + W      L S G  Y  S +     L I     +D+G Y C 
Sbjct: 256  ASLPCVASGVPAPT--ITWTKETNALTSRGPHYNVSKE---GTLLIAQPSAQDAGAYVCT 310

Query: 1921 AINNLGQAVSSIRLNVQSKESI 1942
            A N +G +   +RL+V +K  I
Sbjct: 311  ATNTVGFSSQEMRLSVNTKPRI 332



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 39/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   +  D+GTY+CRA N+ G A   ++L     + G  P+ T   +++  ++ G+SA
Sbjct: 13   LRIPAAQERDAGTYTCRAVNELGDASAEIQL-----AVGHAPQLTELPRDVT-VELGRSA 66

Query: 3168 HFECTVVPVDDPDMKIEWYH-NGQPM---RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
               C       P   + W   +GQP+     + R          VL        D   YV
Sbjct: 67   LLACRA--TGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYV 124

Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254
            C A N +G+    A +   G     + S  P
Sbjct: 125  CEARNVFGKVQAEARLIVTGHAPPQIASSAP 155



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 56/247 (22%), Positives = 86/247 (34%), Gaps = 16/247 (6%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            TG  P         V + EGQ       ++  G       W  +G+ +    R  ++ A 
Sbjct: 143  TGHAPPQIASSAPTVRVLEGQPVSLPC-IVLAGRPLPERHWLKDGRPLPPGSR-HSIRAD 200

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G + L+        +G YSC ATN  G     V+L  V       P  T HI N     +
Sbjct: 201  GSLHLD--RALQEHAGRYSCVATNTAGSQHRDVEL-VVQVPPRIHPTATHHITN-----E 252

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G  A   C    V  P   I W      +        VS  G ++  IA     D+G YV
Sbjct: 253  GVPASLPCVASGVPAPT--ITWTKETNALTSRGPHYNVSKEGTLL--IAQPSAQDAGAYV 308

Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPK 3283
            C A N  G       ++   K  +++   +   +    ++ +  G +          PP 
Sbjct: 309  CTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVP--LQVTAKAGEEVTLDCEAKGSPPP 366

Query: 3284 FITQIQD 3290
             +T  +D
Sbjct: 367  LVTWTKD 373



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 8/109 (7%)

Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
           + PPQ      +V  +EG  +     I   G P  +  WLK+G+ +   SR  SI   G 
Sbjct: 145 HAPPQIASSAPTVRVLEGQPVSLPC-IVLAGRPLPERHWLKDGRPLPPGSRH-SIRADGS 202

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGV--AETKAVLHVTPRATIERTSQH 740
           + LD  +L  + +G Y+C A +  G    + + V+ V PR  I  T+ H
Sbjct: 203 LHLDR-ALQ-EHAGRYSCVATNTAGSQHRDVELVVQVPPR--IHPTATH 247



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 10/104 (9%)

Query: 641 VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLS 700
           VPL+ VTA  G ++  +   E  G P   + W K+ + +   +    +   G  SL +  
Sbjct: 342 VPLQ-VTAKAGEEVTLDC--EAKGSPPPLVTWTKDSRPVPPITNRYGLLPSG--SLRLAQ 396

Query: 701 LNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
           + + DSG Y C A +  G A  + VL V       RTS  P++L
Sbjct: 397 VQVGDSGHYECTASNPAGSASHRYVLGVQ-----GRTSWQPQSL 435



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 17/34 (50%), Positives = 17/34 (50%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            P    LP  VTVE G  A   CR TG P P V W
Sbjct: 49   PQLTELPRDVTVELGRSALLACRATGRPPPTVTW 82



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 37/153 (24%), Positives = 59/153 (38%), Gaps = 13/153 (8%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP    T +  I +E   A   C  +     +  + W      L +      ++  G ++
Sbjct: 238  PPRIHPTATHHITNEGVPASLPC--VASGVPAPTITWTKETNALTSRGPHYNVSKEGTLL 295

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
              I     +DAG Y C ATN  G ++   +L V  +  I        H      +   L+
Sbjct: 296  --IAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRI--------HMNGSRNADVPLQ 345

Query: 3677 ETLHKREEITIEDE-KPNPPRFTVEIKDNIDVP 3708
             T    EE+T++ E K +PP      KD+  VP
Sbjct: 346  VTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVP 378



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQAT 994
           V W KD RPV   +        G  +L +  V V D+GHY C A N  G A+
Sbjct: 368 VTWTKDSRPVPPITNRYGLLPSG--SLRLAQVQVGDSGHYECTASNPAGSAS 417



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 16/33 (48%), Positives = 20/33 (60%)

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            L +      D+GTYTCRA+NELG+A     L V
Sbjct: 13   LRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 45



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 10/92 (10%)

Query: 3695 PRFTVEIKDNIDVP------EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748
            PR  +    N DVP       G  V  DC  E  G P   + W  + RP    +  + L 
Sbjct: 330  PRIHMNGSRNADVPLQVTAKAGEEVTLDC--EAKGSPPPLVTWTKDSRPVPPITNRYGLL 387

Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
              G  +L +  +   D+G Y C A+N  GSA+
Sbjct: 388  PSG--SLRLAQVQVGDSGHYECTASNPAGSAS 417



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 15/33 (45%), Positives = 20/33 (60%)

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I    +RDAG YTC+A N  G+A+   +L V
Sbjct: 13   LRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 45



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 4/76 (5%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +  K G+ +  +C  + S  P   + W  +++P+P  T           SL +      D
Sbjct: 346  VTAKAGEEVTLDCEAKGSPPPL--VTWTKDSRPVPPITNRYGLLPSG--SLRLAQVQVGD 401

Query: 2843 SGIYTCKATNSKGSAT 2858
            SG Y C A+N  GSA+
Sbjct: 402  SGHYECTASNPAGSAS 417



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 8/115 (6%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D   Y C A N +G+ +   +L     +    P+  +    +  L +GQ     C +V  
Sbjct: 119  DQAPYVCEARNVFGKVQAEARLIVTGHA---PPQIASSAPTVRVL-EGQPVSLPC-IVLA 173

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              P  +  W  +G+P+   +R    +D G + LD A  Q H +G Y C A N  G
Sbjct: 174  GRPLPERHWLKDGRPLPPGSRHSIRAD-GSLHLDRA-LQEH-AGRYSCVATNTAG 225



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 5/111 (4%)

Query: 1969 QDDSFVVEKPQFGKPIKNAEVT-EGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK 2027
            +D   VV+ P    P     +T EG P  L    + V  PT+      N     +G  + 
Sbjct: 229  RDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNAL-TSRGPHYN 287

Query: 2028 TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD 2078
             + +     L I    A+D G Y+C ATN VG +     + V+ K  ++++
Sbjct: 288  VSKEG---TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMN 335


>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
          Length = 2828

 Score =  100 bits (240), Expect = 1e-19
 Identities = 108/415 (26%), Positives = 165/415 (39%), Gaps = 35/415 (8%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST--KS 4466
            KP I TK  Q   V       F  E  G+P P + W + +     +P+ +I  F      
Sbjct: 1852 KPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNG 1911

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
             L+IR+V V+D   +   A N  G  +    L V  ++ Q    I+   +    Q+V V 
Sbjct: 1912 TLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQ----ILASHY----QDVTVY 1963

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDI---RNKILEEDGTYTLLILEAYPQDSGK 4583
             G  + ++    GT    + W+   ++V   +    ++I   +   TL I EA   D G 
Sbjct: 1964 LGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENR-TLSIKEASFSDRGV 2022

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII-EPLKDKIVAEGQAIEF 4642
            Y+CVA N+AG                D    +   A  PP I  E L++  +  G +I  
Sbjct: 2023 YKCVASNAAGA---------------DSLAIRLHVAALPPVIHQEKLENISLPPGLSIHI 2067

Query: 4643 SCKIVGKPLPTVQWYKGDKL-IKPSKYFQMSRTA-DEYTLRISEAFPEDEGDYKCVAYNS 4700
             C     PLP+V+W  GD   I+PS++   +       TL I    P+D G Y+CVA N 
Sbjct: 2068 HCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANL 2127

Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW-LREGA 4759
             G      +L V +      +   +P R  V Y G   +     +    P I W L    
Sbjct: 2128 VGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGT-LKLDCSASGDPWPRILWRLPSKR 2186

Query: 4760 LIPETPDFQM-IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +I     F   I    N  L++ +  ++D G + C A    G      K+ V  K
Sbjct: 2187 MIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMK 2241



 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 114/500 (22%), Positives = 195/500 (39%), Gaps = 48/500 (9%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            GG  K +    G+P P + W      +++         +   + +L++K +   D G+Y 
Sbjct: 2161 GGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYL 2220

Query: 146  CTARNQYGE--AICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQ 203
            C ARN+ G+   +  V +  +              +      V+  A G        S  
Sbjct: 2221 CVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLP 2280

Query: 204  TQKV--AYTNGTDHSS-TDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSL 260
               +  ++    D    T  + V         EV  RE        E+ V       R  
Sbjct: 2281 DGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVK 2340

Query: 261  GPVSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI--NSNKHEIITT 317
               +P  I  K   + ++  G       +  G P P+VTW     ++I  +S K++I   
Sbjct: 2341 VVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQI--- 2397

Query: 318  HNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR 377
            +   TL ++  Q+SDSG+YT        C+V +          S  +D+++ +I      
Sbjct: 2398 YQDGTLLIQKAQRSDSGNYT--------CLVRN----------SAGEDRKTVWI------ 2433

Query: 378  ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRF-DCRVTGRPYPEVTWFINDRQIRDD- 435
                 + +    +      +   R++  G   +  DC+  G P P V W   +  +    
Sbjct: 2434 ----HVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAP 2489

Query: 436  -YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             Y ++I V+  GN +L I ++  SDS  + C+ARN+ GE     +L V+E  +   P F 
Sbjct: 2490 YYGNRITVH--GNGSLDIRSLRKSDSVQLVCMARNEGGEARLIVQLTVLEPME--KPIFH 2545

Query: 495  ERFS-TLNVREGEPVVLNARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPR 552
            +  S  +    G  + LN  A GTPTP + W   +G  +    +L+         L I  
Sbjct: 2546 DPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISG 2605

Query: 553  AKASDAAWYQCTAQNVAGST 572
              + DA  Y+C A+N AG T
Sbjct: 2606 LSSVDAGAYRCVARNAAGHT 2625



 Score = 85.8 bits (203), Expect = 3e-15
 Identities = 108/420 (25%), Positives = 156/420 (37%), Gaps = 26/420 (6%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            V+  +KP+K  I  K+    +VF     + +    G P P I W   +  + NS   Q  
Sbjct: 2236 VDVVMKPAK--IEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNS-FMQSD 2292

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL-- 4518
                ++   +  VF   +  F  V     G   C A   V +   + R  +V    T+  
Sbjct: 2293 DSGGRTKRYV--VFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRN 2350

Query: 4519 -TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLLILEA 4576
             T   V V  G +V +  +  G     V WL    KV P    K  + +DGT  LLI +A
Sbjct: 2351 KTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGT--LLIQKA 2408

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
               DSG Y C+  NSAGE R      V +      PK      N  P  I  +++ I A 
Sbjct: 2409 QRSDSGNYTCLVRNSAGEDR----KTVWIHVNVQPPK-----INGNPNPITTVRE-IAAG 2458

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA-DEYTLRISEAFPEDEGDYKC 4695
            G      CK  G P P V W   + ++ P+ Y+    T     +L I      D     C
Sbjct: 2459 GSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVC 2518

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD-IVVYEGQPAQFKTQITSKIKPTIQW 4754
            +A N  G   +  +L V +P +        P+ + I    G              P++ W
Sbjct: 2519 MARNEGGEARLIVQLTVLEPMEKPIFH--DPISEKITAMAGHTISLNCSAAGTPTPSLVW 2576

Query: 4755 -LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             L  G  +      Q  +   + +L I      D G + C A  AAG  E    L V  K
Sbjct: 2577 VLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLK 2636



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 116/506 (22%), Positives = 189/506 (37%), Gaps = 57/506 (11%)

Query: 91   FEGKLRGNPTPVVSWTR-KKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149
            F  +  G P P V+WT+     L+  N    R+ E   + +L+I+++   D G+Y CTA 
Sbjct: 1873 FPCEATGKPKPFVTWTKVSTGALMTPNTRIQRF-EVLKNGTLVIRKVQVQDRGQYMCTAS 1931

Query: 150  NQYG--EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKV 207
            N +G    +  + +  +              Y   +  +E  A GT           ++V
Sbjct: 1932 NLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRV 1991

Query: 208  AYTNGTDHSSTDDFKVDTFEYRLL--REVSFRESITKRYVGESDVQISTEIDRSLGPVSP 265
              T      S  + ++   E R L  +E SF +    + V  +     +   R      P
Sbjct: 1992 WQT-----VSPVESRITLHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALP 2046

Query: 266  PKIAQ-KPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK--HEIITTHNHTT 322
            P I Q K  N  L  G            P P V W       I  ++  H  +    + T
Sbjct: 2047 PVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGT 2106

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +RN    DSG Y  +A N    +V S    V+   +    + R   IT T  R T   
Sbjct: 2107 LYIRNLAPKDSGRYECVAAN----LVGSARRTVQLNVQRAAANAR---ITGTSPRRT--- 2156

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD-YNHKIL 441
                               DV  G   + DC  +G P+P + W +  +++ D  ++    
Sbjct: 2157 -------------------DVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSR 2197

Query: 442  VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
            +    N  L++ +VT  D+G   CVARNK G+     +++V+ K   +  K     +   
Sbjct: 2198 IKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHK---EENDHK 2254

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS---------TLDIPR 552
            V  G  + ++  A G P P I+W      ++ N  ++    GG +         TL    
Sbjct: 2255 VFYGGDLKVDCVATGLPNPEISWSLPDGSLV-NSFMQSDDSGGRTKRYVVFNNGTLYFNE 2313

Query: 553  AKASDAAWYQCTAQNVAGSTATRARL 578
                +   Y C A+N  G    R R+
Sbjct: 2314 VGMREEGDYTCFAENQVGKDEMRVRV 2339



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 88/312 (28%), Positives = 127/312 (40%), Gaps = 31/312 (9%)

Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK--NGKKVQPDIRNKILEEDG 4567
            G  P   T + Q V+VT+        + TG     V W K   G  + P+ R +  E   
Sbjct: 1850 GEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLK 1909

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
              TL+I +   QD G+Y C A N  G  R     VV L  T  +P  Q  A++       
Sbjct: 1910 NGTLVIRKVQVQDRGQYMCTASNLHGLDRM----VVLLSVTVQQP--QILASH------- 1956

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA--DEYTLRISEA 4685
              +D  V  G  I   C   G P P + W   D+ +  +     SR    +  TL I EA
Sbjct: 1957 -YQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEA 2015

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQIT 4745
               D G YKCVA N+AG  ++A +L V       +   L    +I +  G          
Sbjct: 2016 SFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKL---ENISLPPGLSIHIHCTAK 2072

Query: 4746 SKIKPTIQW-LREGALIPETPDFQMIHEGN-----NAVLLIGNTYEEDTGTFTCRATTAA 4799
            +   P+++W L +G  I  +   Q +H GN     N  L I N   +D+G + C A    
Sbjct: 2073 AAPLPSVRWVLGDGTQIRPS---QFLH-GNLFVFPNGTLYIRNLAPKDSGRYECVAANLV 2128

Query: 4800 GQVETSAKLVVK 4811
            G    + +L V+
Sbjct: 2129 GSARRTVQLNVQ 2140



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 103/423 (24%), Positives = 155/423 (36%), Gaps = 43/423 (10%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN--SPDFQIHTF 4462
            V   +P I     Q   V+  +    E    G P P I W   +  +    SP     T 
Sbjct: 1945 VTVQQPQILASHYQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITL 2004

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
                 L I++    D  V+  VA N  G    +  L V          + P       +N
Sbjct: 2005 HENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHV--------AALPPVIHQEKLEN 2056

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKVQPDI---RNKILEEDGTYTLLILEAYP 4578
            +++  G  + +           V W L +G +++P      N  +  +GT  L I    P
Sbjct: 2057 ISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGT--LYIRNLAP 2114

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
            +DSG+YECVA N  G AR   +  V           Q  AANA      P +   V  G 
Sbjct: 2115 KDSGRYECVAANLVGSARRTVQLNV-----------QRAAANARITGTSPRRTD-VRYGG 2162

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR--TADEYTLRISEAFPEDEGDYKCV 4696
             ++  C   G P P + W    K +  + +   SR       TL +     +D GDY CV
Sbjct: 2163 TLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCV 2222

Query: 4697 AYNSAGRVTVAAKLKVT-QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW- 4754
            A N  G   V  K+ V  +P + ++        D  V+ G   +     T    P I W 
Sbjct: 2223 ARNKVGDDYVVLKVDVVMKPAKIEHKEE----NDHKVFYGGDLKVDCVATGLPNPEISWS 2278

Query: 4755 LREGALI---PETPD----FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            L +G+L+    ++ D     +     NN  L        + G +TC A    G+ E   +
Sbjct: 2279 LPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVR 2338

Query: 4808 LVV 4810
            + V
Sbjct: 2339 VKV 2341



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 91/386 (23%), Positives = 142/386 (36%), Gaps = 34/386 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPI--KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E  GEP+P + W      +   +S  +QI+   T   L+I++    DS  +  +  N  G
Sbjct: 2369 EAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGT---LLIQKAQRSDSGNYTCLVRNSAG 2425

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LK 4549
              + +  + V  +  +  G    P+   T + +    G    +D K  G     V W   
Sbjct: 2426 EDRKTVWIHVNVQPPKINGN---PNPITTVREI-AAGGSRKLIDCKAEGIPTPRVLWAFP 2481

Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             G  +        +   G  +L I      DS +  C+A N  GEAR   +  V  P  K
Sbjct: 2482 EGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLIVQLTVLEPMEK 2541

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWY--KGDKLIKPS 4666
                         P   +P+ +KI A  G  I  +C   G P P++ W    G  L    
Sbjct: 2542 -------------PIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQ 2588

Query: 4667 KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP 4726
            +  +    AD   L IS     D G Y+CVA N+AG       LKV    +A+       
Sbjct: 2589 QLQRFYHKADGM-LHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEANK-----Q 2642

Query: 4727 LRDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD-FQMIHEGNNAVLLIGNTY 4784
              ++V +  G+  +         +    W     +  E P     +   +N  L +    
Sbjct: 2643 YHNLVSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREAS 2702

Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVV 4810
              D GT+ CR  T  G   TS  ++V
Sbjct: 2703 VFDRGTYVCRMETEYGPSVTSIPVIV 2728



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 60/194 (30%), Positives = 84/194 (43%), Gaps = 11/194 (5%)

Query: 392  PQFV-KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES-GNHA 449
            PQ + K  Q   VT    T F C  TG+P P VTW           N +I   E   N  
Sbjct: 1853 PQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGT 1912

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-IEKEQVVAPKFVERFSTLNVREGEPV 508
            L+I  V + D G   C A N  G       L+V +++ Q++A      +  + V  G+ +
Sbjct: 1913 LVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILA----SHYQDVTVYLGDTI 1968

Query: 509  VLNARAVGTPTPRITW---QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             +   A GTP P+I+W    +     +   E RI T     TL I  A  SD   Y+C A
Sbjct: 1969 AMECLAKGTPAPQISWIFPDRRVWQTVSPVESRI-TLHENRTLSIKEASFSDRGVYKCVA 2027

Query: 566  QNVAGSTATRARLY 579
             N AG+ +   RL+
Sbjct: 2028 SNAAGADSLAIRLH 2041



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 56/221 (25%), Positives = 90/221 (40%), Gaps = 11/221 (4%)

Query: 356 ESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRV 415
           +S  +  +    +QY      ++T +    S   + P    V +D+ V EG   +  C V
Sbjct: 445 QSTAKKVLLSYYTQYSQTISTKDTRQARGRSWVMIEPSGA-VQRDQTVLEGGPCQLSCNV 503

Query: 416 TGRPYPEVTWFINDRQI----RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
                P + W + D  I     DD + K  +  SG   L I ++  SDSG+  C+A+ + 
Sbjct: 504 KASESPSIFWVLPDGSILKAPMDDPDSKFSILSSG--WLRIKSMEPSDSGLYQCIAQVRD 561

Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
                  R+ V       A K      T+    GE V L   A+  P   ++W      I
Sbjct: 562 EMDRMVYRVLVQSPSTQPAEKDTV---TIGKNPGESVTLPCNALAIPEAHLSWILPNRRI 618

Query: 532 IPNPELRIHTDGGAS-TLDIPRAKASDAAWYQCTAQNVAGS 571
           I +     H     + TL IP+ + SD+ +Y+C A N  G+
Sbjct: 619 INDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQGA 659



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 11/190 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFY-NGKTIEASHRIRTVYAFGMV 3106
            P F     + +    G       S   T   S+V  W   NG  +++  +++  Y     
Sbjct: 2542 PIFHDPISEKITAMAGHTISLNCSAAGTPTPSLV--WVLPNGTDLQSGQQLQRFYHKADG 2599

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I G  + D+G Y C A N  G  E  V L+      G KP       N+  + +G++
Sbjct: 2600 MLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV-----GLKPEANKQYHNLVSIINGET 2654

Query: 3167 AHFECTVVPVDDPDMKIEW-YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                CT  P      +  W   NG  +     +  VS      L +      D G YVCR
Sbjct: 2655 LKLPCT--PPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCR 2712

Query: 3226 AYNKYGEDFT 3235
               +YG   T
Sbjct: 2713 METEYGPSVT 2722



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 7/193 (3%)

Query: 3039 QPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR 3098
            QP    G P   TTV ++I      ++   +A  IPT     V+  F  G  + A +   
Sbjct: 2438 QPPKINGNPNPITTV-REIAAGGSRKLIDCKAEGIPT---PRVLWAFPEGVVLPAPYYGN 2493

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
             +   G   L+I   + +DS    C A N+ G+A + V+L  ++    +KP F   I   
Sbjct: 2494 RITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLIVQLTVLEPM--EKPIFHDPISEK 2551

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
                 G +    C+      P + +    NG  ++   +++        +L I+   + D
Sbjct: 2552 ITAMAGHTISLNCSAAGTPTPSL-VWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVD 2610

Query: 3219 SGEYVCRAYNKYG 3231
            +G Y C A N  G
Sbjct: 2611 AGAYRCVARNAAG 2623



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 5/141 (3%)

Query: 347 IVTSGYLAVES--PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVT 404
           I++SG+L ++S  P++S +    +Q + D   R    R+ +   +  P   K        
Sbjct: 534 ILSSGWLRIKSMEPSDSGLYQCIAQ-VRDEMDRMVY-RVLVQSPSTQPA-EKDTVTIGKN 590

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
            G+     C     P   ++W + +R+I +D  +   V    N  L I  V +SDSG   
Sbjct: 591 PGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYR 650

Query: 465 CVARNKSGETAFQCRLNVIEK 485
           CVA N+ G   F   + V +K
Sbjct: 651 CVAVNQQGADHFTVGITVTKK 671



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 46/199 (23%), Positives = 74/199 (37%), Gaps = 14/199 (7%)

Query: 381  ERIEISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
            ER+   +  L P+  K   +   +  G+  +  C   G      +W + +    +     
Sbjct: 2626 ERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTL 2685

Query: 440  ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
              V+   N  L +   ++ D G   C    + G +     + VI     +     E    
Sbjct: 2686 GRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITS---EPTPV 2742

Query: 500  LNVREGEPVVLNARAVGTPTPRITWQ-------KDGVPIIPNPELRIHTDGGASTLDIPR 552
            +  R G  V LN  A+G P   ITW+       K GV         +H  G   +L I  
Sbjct: 2743 IYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQG---SLTIQH 2799

Query: 553  AKASDAAWYQCTAQNVAGS 571
            A   DA +Y+C A+N+ GS
Sbjct: 2800 ATQRDAGFYKCMAKNILGS 2818



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 4/100 (4%)

Query: 1975 VEKPQFGKPI-KNAEVTEGHPVHLEATLTPVNDPTMRVEWYC-NGRPVQQGHRFKTTYDF 2032
            +EKP F  PI +      GH + L  +      PT  + W   NG  +Q G + +  Y  
Sbjct: 2539 MEKPIFHDPISEKITAMAGHTISLNCSAA--GTPTPSLVWVLPNGTDLQSGQQLQRFYHK 2596

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
                L I    + D G Y C A NA G      S+KV  K
Sbjct: 2597 ADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLK 2636



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 14/160 (8%)

Query: 3082 IEWFY-NGKTIEASHRIR-TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
            + W   +G  I  S  +   ++ F    L I      DSG Y C A N  G A  +V+L 
Sbjct: 2079 VRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLN 2138

Query: 3140 CVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-----RH 3194
               +      R T        ++ G +   +C+     DP  +I W    + M       
Sbjct: 2139 V--QRAAANARITGTSPRRTDVRYGGTLKLDCSAS--GDPWPRILWRLPSKRMIDALFSF 2194

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
             +RIK  ++   VV  +    + D+G+Y+C A NK G+D+
Sbjct: 2195 DSRIKVFANGTLVVKSVT---DKDAGDYLCVARNKVGDDY 2231



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 5/93 (5%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEW-FHNGRSVTVGSRFKTYYDFGF 1234
            KP+F  P+S       G  I L C     G PT  + W   NG  +  G + + +Y    
Sbjct: 2541 KPIFHDPISEKITAMAGHTISLNC--SAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKAD 2598

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267
              L I   +S D G Y  R V    + HT  +V
Sbjct: 2599 GMLHISGLSSVDAGAY--RCVARNAAGHTERLV 2629



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF--AALDILTVYGED 1913
            L  G S H  C  +  P P++R  W           ++   N F F    L I  +  +D
Sbjct: 2059 LPPGLSIHIHCTAKAAPLPSVR--WVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKD 2116

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQ 1937
            SG Y C A N +G A  +++LNVQ
Sbjct: 2117 SGRYECVAANLVGSARRTVQLNVQ 2140



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 3/106 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEW-LKDGRPVEASSRITT 960
            V E  +KP F  PI ++I+   G            G  T  + W L +G  +++  ++  
Sbjct: 2535 VLEPMEKPIFHDPISEKITAMAGHTISLNC--SAAGTPTPSLVWVLPNGTDLQSGQQLQR 2592

Query: 961  FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
            F++     L I  ++  DAG Y C A NA G      +L +  K +
Sbjct: 2593 FYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPE 2638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 58/214 (27%), Positives = 88/214 (41%), Gaps = 27/214 (12%)

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT----SSTLFVQSKASLQLESQHES 1816
            T+ +  Y+A+ + Y    D  T  C A  E    VT    ++ +   S    Q+      
Sbjct: 2347 TIRNKTYLAVQVPY---GDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTL 2403

Query: 1817 ALQKIQQLEDSSRY---------QRREDVEVAVN-QAPRFITQLNGPTKLSE----GQSA 1862
             +QK Q+  DS  Y         + R+ V + VN Q P+     N  T + E    G   
Sbjct: 2404 LIQKAQR-SDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRK 2462

Query: 1863 HYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
              +C+ E  P P  RV W F  G VL + +        G  +LDI ++   DS +  C A
Sbjct: 2463 LIDCKAEGIPTP--RVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMA 2520

Query: 1922 INNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
             N  G+A   ++L V   E + +   H+   EKI
Sbjct: 2521 RNEGGEARLIVQLTV--LEPMEKPIFHDPISEKI 2552



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 2/73 (2%)

Query: 84   AQGGNAKF-EGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
            A GG+ K  + K  G PTP V W   +  ++    Y  R     G+ SL I+ +   D  
Sbjct: 2456 AAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVH-GNGSLDIRSLRKSDSV 2514

Query: 143  EYTCTARNQYGEA 155
            +  C ARN+ GEA
Sbjct: 2515 QLVCMARNEGGEA 2527



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF-NGKQITSANRIQTYHDFG 1099
            +KP F  P+  + KI                  T ++ W   NG  + S  ++Q ++   
Sbjct: 2540 EKPIFHDPI--SEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKA 2597

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
               L I+ + + D+G Y  VARNAAG  +   S+ V
Sbjct: 2598 DGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 2633



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 4/94 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW-FHNGRPFATGSRVH-TLNDFG 3751
            PP    E  +NI +P G  +H  C  +    P++R  W   +G        +H  L  F 
Sbjct: 2046 PPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVR--WVLGDGTQIRPSQFLHGNLFVFP 2103

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               L I  +  +D+G Y C A N  GSA  T ++
Sbjct: 2104 NGTLYIRNLAPKDSGRYECVAANLVGSARRTVQL 2137



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 41/203 (20%), Positives = 73/203 (35%), Gaps = 13/203 (6%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFY-NGKTIEASHRIRTVYAF 3103
            G  PE    + ++V I  G+      +  P G       W   NG  +E    +  V   
Sbjct: 2634 GLKPEANKQYHNLVSIINGETLKLPCT--PPGAGQGRFSWTLPNGMHLEGPQTLGRVSLL 2691

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L +      D GTY CR   ++G +  S+ +  +       PR T+    +   + 
Sbjct: 2692 DNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVI----AYPPRITSEPTPVIYTRP 2747

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV----VLDIAYTQNHDS 3219
            G +    C  + +   D+  E   +   ++   + +   +  F+     L I +    D+
Sbjct: 2748 GNTVKLNCMAMGIPKADITWE-LPDKSHLKAGVQARLYGN-RFLHPQGSLTIQHATQRDA 2805

Query: 3220 GEYVCRAYNKYGEDFTRATINCY 3242
            G Y C A N  G D     I+ +
Sbjct: 2806 GFYKCMAKNILGSDSKTTYIHVF 2828



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 41/267 (15%)

Query: 4501 EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKVQ---- 4555
            + ++ +GR  ++        ++  V  G   +L   V  ++   ++W L +G  ++    
Sbjct: 467  DTRQARGRSWVMIEPSGAVQRDQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMD 526

Query: 4556 -PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             PD +  IL       L I    P DSG Y+C+A       R     +V  P+T+   K 
Sbjct: 527  DPDSKFSILSSGW---LRIKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQPAEKD 583

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
                   P              G+++   C  +  P   + W   ++ I       ++ T
Sbjct: 584  TVTIGKNP--------------GESVTLPCNALAIPEAHLSWILPNRRI----INDLANT 625

Query: 4675 ADEY-----TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-----PDQADNLP-- 4722
            +  Y     TL I +    D G Y+CVA N  G       + VT+     P +    P  
Sbjct: 626  SHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQGADHFTVGITVTKKGSGLPSKRGRRPGA 685

Query: 4723 -ALTPLR-DIVVYEGQPAQFKTQITSK 4747
             AL+ +R DIV  EG       + TS+
Sbjct: 686  KALSRVREDIVEDEGGSGMGDEENTSR 712



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 3/99 (3%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYW-NGKSLKAGSRFRTFC 3473
            E  + P+F  P+S       G           T  P+L   W   NG  L++G + + F 
Sbjct: 2537 EPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLV--WVLPNGTDLQSGQQLQRFY 2594

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
                 +L IS     D+G Y C A N  G      S+KV
Sbjct: 2595 HKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 2633



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 27/73 (36%), Positives = 34/73 (46%), Gaps = 8/73 (10%)

Query: 937  GDSTLRVEW-LKDGRPVEA----SSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            GD   R+ W L   R ++A     SRI  F N     L +KSVT  DAG Y C A N +G
Sbjct: 2172 GDPWPRILWRLPSKRMIDALFSFDSRIKVFANG---TLVVKSVTDKDAGDYLCVARNKVG 2228

Query: 992  QATTSANLTIVTK 1004
                   + +V K
Sbjct: 2229 DDYVVLKVDVVMK 2241



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 1/95 (1%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            + PIF   +      + G  + L         P+L +    NG  L +G +L+  +    
Sbjct: 2540 EKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSL-VWVLPNGTDLQSGQQLQRFYHKAD 2598

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
              L I+ L + D+G Y C A N  G      S+K+
Sbjct: 2599 GMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 2633



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 637  PQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEW-LKNGQSIEASSRFTSIFRFGYI 694
            P F  P+ + +TAM G  I         G PT  + W L NG  +++  +    +     
Sbjct: 2542 PIFHDPISEKITAMAGHTISLNC--SAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADG 2599

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             L +  L+  D+G Y C A +A G  E    L V
Sbjct: 2600 MLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 2633



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 4/98 (4%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEW--FFNGKPLLHKNRFTPIYDF 4028
            + P+ +T+     S+     T F C+    G P   V W     G  +    R       
Sbjct: 1851 EKPQILTKSPQTVSVTAETDTVFPCEAT--GKPKPFVTWTKVSTGALMTPNTRIQRFEVL 1908

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
                +    V  +D G+Y+C A+NL+G+D    ++  T
Sbjct: 1909 KNGTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVT 1946



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYI-NGVELKMGSRFRTTHDFG 2564
            EKPIF   ++       G              PSL   W + NG +L+ G + +  +   
Sbjct: 2540 EKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSL--VWVLPNGTDLQSGQQLQRFYHKA 2597

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAG 2590
               L I+ + + DAG Y C A N AG
Sbjct: 2598 DGMLHISGLSSVDAGAYRCVARNAAG 2623



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)

Query: 1736 PVGDPKLRVEW-LRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
            P G  + R  W L NG+ +E    L  +       L ++  +  D GTY CR   E G +
Sbjct: 2661 PPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPS 2720

Query: 1795 VTSSTLFV 1802
            VTS  + V
Sbjct: 2721 VTSIPVIV 2728


>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
            protein.
          Length = 1340

 Score =   99 bits (238), Expect = 2e-19
 Identities = 99/402 (24%), Positives = 163/402 (40%), Gaps = 42/402 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+    +      E   A    +  G P P I W ++  P+  +      T      L+
Sbjct: 934  PPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGK--FTIQPSGELL 991

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            ++ +  +D+  +   AEN  G A+   +L +          +V P FT    + ++  G 
Sbjct: 992  VKNLEGQDAGTYTCTAENAVGRARRRVHLTI----------LVLPVFTTLPGDRSLRLGD 1041

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             + L     G+    + W  N + V   +     E+DG  TL       +DSG Y C A 
Sbjct: 1042 RLWLRCAARGSPTPRIGWTVNDRPVTEGVS----EQDGGSTLQRAAVSREDSGTYVCWAE 1097

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N  G  +      VS    K+ P  Q +A +    ++EP+       G +I+  C + G 
Sbjct: 1098 NRVGRTQA-----VSFVHVKEAPVLQGEAFSY---LVEPV-------GGSIQLDCVVRGD 1142

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P+P + W K D L  P +   +       +L I     +D G Y+C+A N  G     AK
Sbjct: 1143 PVPDIHWIK-DGL--PLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMG----VAK 1195

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
              V    Q+  +  + P +D+ V  G     + Q T +  PTI+WL+ G  +  +   + 
Sbjct: 1196 KVVILVLQSAPVFQVEP-QDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRT 1254

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + +G+   L + N    D GT+ C A    G     A LVV+
Sbjct: 1255 LPDGS---LWLENVETGDAGTYDCVAHNLLGSATARAFLVVR 1293



 Score = 97.9 bits (233), Expect = 8e-19
 Identities = 101/378 (26%), Positives = 140/378 (37%), Gaps = 38/378 (10%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E  G P PL+ W+++   +        +     + L++     +DSA F  V  N  G A
Sbjct: 683  EASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEA 742

Query: 4493 KCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGK 4552
                 + V           VPP+      +  VT    V L    TG     V W K G 
Sbjct: 743  HRLYQVTVH----------VPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAG- 791

Query: 4553 KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
              Q   R        +  L I +A P  +G+Y C A NSAG A       V       KP
Sbjct: 792  -AQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVV-KP 849

Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672
             P    A A  E++ P               C+  G P PT+ W K    +      Q+ 
Sbjct: 850  LPSVVRAVAEEEVLLP---------------CEASGIPRPTITWQKEGLNVATGVSTQVL 894

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
                   LRI+ A PED G+Y C+A NSAG      +L V  P   +N      L D+  
Sbjct: 895  PGGQ---LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIEN-----GLPDLST 946

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
             EG  A    +     +P I W ++G  +        I       LL+ N   +D GT+T
Sbjct: 947  TEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE--LLVKNLEGQDAGTYT 1004

Query: 4793 CRATTAAGQVETSAKLVV 4810
            C A  A G+      L +
Sbjct: 1005 CTAENAVGRARRRVHLTI 1022



 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 106/391 (27%), Positives = 163/391 (41%), Gaps = 65/391 (16%)

Query: 4425 HEQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            ++ A    + DG P PL+ W ++  P+   SP F+I     +  L I+ V  +D+  +  
Sbjct: 603  NQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEI---LPEGSLRIQPVLAQDAGHYLC 659

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT-KP 4542
            +A N  G+             RQGR             ++ V    L  L  + +G+ KP
Sbjct: 660  LASNSAGSD------------RQGR-------------DLRV----LALLPCEASGSPKP 690

Query: 4543 IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
            + V+W K+G+K+   ++        +  LL+    PQDS ++ECV  N  GEA    +  
Sbjct: 691  LVVWW-KDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVT 749

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDK 4661
            V                + PP I +   D  V     +  +C   G P PTV W K G +
Sbjct: 750  V----------------HVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 793

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
            L      +++S +     L I +A P   G Y C A NSAG   VA K  V    QA   
Sbjct: 794  LGARGSGYRVSPSG---ALEIGQALPIHAGRYTCSARNSAG---VAHK-HVFLTVQAS-- 844

Query: 4722 PALTPLRDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
            P + PL  +V     +      + +   +PTI W +EG  +      Q++  G    L I
Sbjct: 845  PVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ---LRI 901

Query: 4781 GNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +   ED G + C A  +AG      +LVV+
Sbjct: 902  AHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 932



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 52/174 (29%), Positives = 84/174 (48%), Gaps = 5/174 (2%)

Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
           V ++  V EG+  R DC   G+P P+V W  +   +  D    +     G  +L++  + 
Sbjct: 136 VAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-SLVLKGLW 194

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            SD+G  TCVA N +GE A    +NV+    +   +  +   TL  R GE V +     G
Sbjct: 195 ASDAGAYTCVAHNPAGEDARLHTVNVLVPPTI--KQGADGSGTLVSRPGELVTMVCPVRG 252

Query: 517 TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           +P   ++W KDG+P+  +    +H  G   TL I + + +DA  + C A + AG
Sbjct: 253 SPPIHVSWLKDGLPLPLSQRTLLH--GSGHTLRISKVQLADAGIFTCVAASPAG 304



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 92/393 (23%), Positives = 144/393 (36%), Gaps = 44/393 (11%)

Query: 4421 RVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAV 4480
            R    E+     E  G P P I W +E   +      Q+        L I     ED+  
Sbjct: 855  RAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ---LRIAHASPEDAGN 911

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
            +  +A+N  G+A     LVV+          VPP       +++ T G    L  K  G+
Sbjct: 912  YLCIAKNSAGSAMGKTRLVVQ----------VPPVIENGLPDLSTTEGSHAFLPCKARGS 961

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
               ++ W K+G+ V        ++  G   LL+     QD+G Y C A N+ G AR    
Sbjct: 962  PEPNITWDKDGQPVSGAEGKFTIQPSG--ELLVKNLEGQDAGTYTCTAENAVGRARRRVH 1019

Query: 4601 -CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
              ++ LP     P                  D+ +  G  +   C   G P P + W   
Sbjct: 1020 LTILVLPVFTTLP-----------------GDRSLRLGDRLWLRCAARGSPTPRIGWTVN 1062

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
            D+ +       +S      TL+ +    ED G Y C A N  GR    + + V +     
Sbjct: 1063 DRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQ 1118

Query: 4720 NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
               A + L + V   G   Q    +     P I W+++G  +  +    + H+  N  L 
Sbjct: 1119 G-EAFSYLVEPV---GGSIQLDCVVRGDPVPDIHWIKDGLPLRGS---HLRHQLQNGSLT 1171

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            I  T  +D G + C A    G  +    LV++S
Sbjct: 1172 IHRTERDDAGRYQCLAENEMGVAKKVVILVLQS 1204



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 54/173 (31%), Positives = 80/173 (46%), Gaps = 12/173 (6%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
            G   + DC V G P P++ W  +   +R  +    L ++  N +L I      D+G   C
Sbjct: 1130 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSH----LRHQLQNGSLTIHRTERDDAGRYQC 1185

Query: 466  VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
            +A N+ G  A +  + V++     AP F      + VR G+ V L  +A G PTP I W 
Sbjct: 1186 LAENEMG-VAKKVVILVLQS----APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL 1240

Query: 526  KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            + G P+  +  LR   DG   +L +   +  DA  Y C A N+ GS   RA L
Sbjct: 1241 QAGQPLRASRRLRTLPDG---SLWLENVETGDAGTYDCVAHNLLGSATARAFL 1290



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 82/342 (23%), Positives = 133/342 (38%), Gaps = 31/342 (9%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF-TLTAQNVNVT 4526
            L I++  V D  +++    N  G A  +  L V+          VPP+F     + V+  
Sbjct: 1    LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ----------VPPTFENPKTETVSQV 50

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
            +G  + L   V+G     V WLK+   V+    + ++   G   L  L+  P  +G Y C
Sbjct: 51   AGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQ--PAQAGTYTC 108

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VA N+  EAR D    V +        P+ +++          ++  V EGQ +   C+ 
Sbjct: 109  VAENTQAEARKDFVVAVLVA-------PRIRSSGVA-------REHHVLEGQEVRLDCEA 154

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G+P P V W K    +       +    D  +L +   +  D G Y CVA+N AG    
Sbjct: 155  DGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGEDAR 214

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               + V  P              +V   G+       +       + WL++G  +P    
Sbjct: 215  LHTVNVLVPPTIKQ--GADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLP-LSQ 271

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
              ++H G+   L I      D G FTC A + AG  + +  L
Sbjct: 272  RTLLH-GSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTL 312



 Score = 78.2 bits (184), Expect = 7e-13
 Identities = 81/326 (24%), Positives = 132/326 (40%), Gaps = 40/326 (12%)

Query: 4483 AVAENRGGTAKCSANLVVEEKRRQGRGGIV-PPSFTLTAQ--NVNVTSGQLVRLDTKVTG 4539
            AV     GT  C A     E RR  +  ++ PP    + Q   +++T G  + L     G
Sbjct: 373  AVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQG 432

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
            T   ++ W K+G+ +     N       T  L +     +D+G Y C+A + AG      
Sbjct: 433  TPQPNITWHKDGQALTRLENNS----RATRVLRVENVQVRDAGLYTCLAESPAGAIE--- 485

Query: 4600 ECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV---AEGQAIEFSCKIVGKPLPTVQW 4656
                         K       APP I+ P   + V   A GQ +   C +  +P P + W
Sbjct: 486  -------------KSFRVRVQAPPNIVGPRGPRFVVGLAPGQLV-LECSVEAEPAPKITW 531

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQP 4715
            ++   +++   + Q         L++      D GDY C A N+AG  +VA ++++ T P
Sbjct: 532  HRDGIVLQEDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVP 589

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPETPDFQMIHEGN 4774
                  PA+       V   Q A    Q      P + W ++   L P +P F+++ EG+
Sbjct: 590  TIRSGPPAVN------VSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS 643

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAG 4800
               L I     +D G + C A+ +AG
Sbjct: 644  ---LRIQPVLAQDAGHYLCLASNSAG 666



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 12/179 (6%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F  +  DR +  G      C   G P P + W +NDR + +  +      + G   L 
Sbjct: 1026 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQDGGSTLQ 1080

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
               V+  DSG   C A N+ G T     ++V  KE  V     E FS L    G  + L+
Sbjct: 1081 RAAVSREDSGTYVCWAENRVGRTQAVSFVHV--KEAPVLQG--EAFSYLVEPVGGSIQLD 1136

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P I W KDG+P +    LR     G  +L I R +  DA  YQC A+N  G
Sbjct: 1137 CVVRGDPVPDIHWIKDGLP-LRGSHLRHQLQNG--SLTIHRTERDDAGRYQCLAENEMG 1192



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 52/163 (31%), Positives = 75/163 (46%), Gaps = 10/163 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C V+G P P VTW  +   +     H + V+  G   L ++ +  + +G  TCVA N   
Sbjct: 59  CDVSGVPAPTVTWLKDRMPVESSAVHGV-VSRGGR--LQLSRLQPAQAGTYTCVAENTQA 115

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
           E      + V+   ++ +         L   EG+ V L+  A G P P + W KDG P+ 
Sbjct: 116 EARKDFVVAVLVAPRIRSSGVAREHHVL---EGQEVRLDCEADGQPPPDVAWLKDGSPLG 172

Query: 533 PN--PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
            +  P LR + DGG+  L +    ASDA  Y C A N AG  A
Sbjct: 173 QDMGPHLRFYLDGGS--LVLKGLWASDAGAYTCVAHNPAGEDA 213



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 51/173 (29%), Positives = 71/173 (41%), Gaps = 12/173 (6%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
            D   TEG      C+  G P P +TW   D Q       K  +  SG   L++ N+   D
Sbjct: 943  DLSTTEGSHAFLPCKARGSPEPNITWD-KDGQPVSGAEGKFTIQPSGE--LLVKNLEGQD 999

Query: 460  SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519
            +G  TC A N  G    +  L ++     V P F       ++R G+ + L   A G+PT
Sbjct: 1000 AGTYTCTAENAVGRARRRVHLTIL-----VLPVFTTLPGDRSLRLGDRLWLRCAARGSPT 1054

Query: 520  PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            PRI W  +  P+       +    G STL        D+  Y C A+N  G T
Sbjct: 1055 PRIGWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRT 1103



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 48/176 (27%), Positives = 79/176 (44%), Gaps = 10/176 (5%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           +T G      C   G P P +TW  + + +    N     N      L + NV + D+G+
Sbjct: 418 LTPGAPMELLCDAQGTPQPNITWHKDGQALTRLEN-----NSRATRVLRVENVQVRDAGL 472

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TC+A + +G      R+ V     +V P+   RF  + +  G+ +VL       P P+I
Sbjct: 473 YTCLAESPAGAIEKSFRVRVQAPPNIVGPR-GPRF-VVGLAPGQ-LVLECSVEAEPAPKI 529

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           TW +DG+ +  +   +    G    L +     +D+  Y CTA+N AGST+   R+
Sbjct: 530 TWHRDGIVLQEDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVAFRV 583



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 49/161 (30%), Positives = 78/161 (48%), Gaps = 12/161 (7%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           +C V   P P++TW  +   +++D + +    E G   L +  ++ +DSG  +C ARN +
Sbjct: 518 ECSVEAEPAPKITWHRDGIVLQEDAHTQF--PERGRF-LQLQALSTADSGDYSCTARNAA 574

Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
           G T+   R+ +        P        +NV   +  +L  +A G P P ++W+KD VP+
Sbjct: 575 GSTSVAFRVEIH-----TVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPL 629

Query: 532 IP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            P +P   I  +G   +L I    A DA  Y C A N AGS
Sbjct: 630 DPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGS 667



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 73/272 (26%), Positives = 111/272 (40%), Gaps = 29/272 (10%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIH-TFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
            +  G P P + W ++  P+++S    +H   S    L + ++    +  +  VAEN    
Sbjct: 60   DVSGVPAPTVTWLKDRMPVESSA---VHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAE 116

Query: 4492 AKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
            A+    + V    R    G+        A+  +V  GQ VRLD +  G  P DV WLK+G
Sbjct: 117  ARKDFVVAVLVAPRIRSSGV--------AREHHVLEGQEVRLDCEADGQPPPDVAWLKDG 168

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE-ARCDAECVVSLPATKD 4610
              +  D+   +       +L++   +  D+G Y CVA N AGE AR     V+  P  K 
Sbjct: 169  SPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQ 228

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
                     + P              G+ +   C + G P   V W K D L  P     
Sbjct: 229  GADGSGTLVSRP--------------GELVTMVCPVRGSPPIHVSWLK-DGLPLPLSQRT 273

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
            +      +TLRIS+    D G + CVA + AG
Sbjct: 274  LLH-GSGHTLRISKVQLADAGIFTCVAASPAG 304



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 51/176 (28%), Positives = 87/176 (49%), Gaps = 13/176 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E ++ R + E DG+P P + W ++  P+       +  +     L+++ ++  D+  +
Sbjct: 142  VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAY 201

Query: 4482 AAVAENRGG-TAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG 4539
              VA N  G  A+  + N++V    +QG  G    S TL ++      G+LV +   V G
Sbjct: 202  TCVAHNPAGEDARLHTVNVLVPPTIKQGADG----SGTLVSR-----PGELVTMVCPVRG 252

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            + PI V WLK+G  + P  +  +L   G +TL I +    D+G + CVA + AG A
Sbjct: 253  SPPIHVSWLKDGLPL-PLSQRTLLHGSG-HTLRISKVQLADAGIFTCVAASPAGVA 306



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 59/232 (25%), Positives = 97/232 (41%), Gaps = 25/232 (10%)

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            DSG Y CVA++ AGEAR   +  V  P       P  + +  P E+        +  G  
Sbjct: 378  DSGTYSCVAVSEAGEARRHFQLTVMEP-------PHIEDSGQPTEL-------SLTPGAP 423

Query: 4640 IEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            +E  C   G P P + W+K G  L +     + +R      LR+      D G Y C+A 
Sbjct: 424  MELLCDAQGTPQPNITWHKDGQALTRLENNSRATR-----VLRVENVQVRDAGLYTCLAE 478

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
            + AG +  + +++V  P    N+      R +V         +  + ++  P I W R+G
Sbjct: 479  SPAGAIEKSFRVRVQAP---PNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDG 535

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             ++ E    Q    G    L   +T   D+G ++C A  AAG    + ++ +
Sbjct: 536  IVLQEDAHTQFPERGRFLQLQALST--ADSGDYSCTARNAAGSTSVAFRVEI 585



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 48/166 (28%), Positives = 72/166 (43%), Gaps = 11/166 (6%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C  +G P P +TW      +    + ++L        L I + +  D+G   C+A+N +G
Sbjct: 866  CEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ----LRIAHASPEDAGNYLCIAKNSAG 921

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
                + RL V++    V P        L+  EG    L  +A G+P P ITW KDG P +
Sbjct: 922  SAMGKTRL-VVQ----VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQP-V 975

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               E +  T   +  L +   +  DA  Y CTA+N  G    R  L
Sbjct: 976  SGAEGKF-TIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHL 1020



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 88/342 (25%), Positives = 135/342 (39%), Gaps = 45/342 (13%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFD--GEPLPLIKWYRENFPIKNSPDFQIHTFSTKS 4466
            +PP      QP  +     A  E+  D  G P P I W+++   +      + ++ +T+ 
Sbjct: 403  EPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR---LENNSRATR- 458

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
            +L +  V V D+ ++  +AE+  G  + S  +     R Q    IV P        V + 
Sbjct: 459  VLRVENVQVRDAGLYTCLAESPAGAIEKSFRV-----RVQAPPNIVGPRGPRFV--VGLA 511

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             GQLV L+  V       + W ++G  +Q D   +  E      L  L     DSG Y C
Sbjct: 512  PGQLV-LECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALST--ADSGDYSC 568

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
             A N+AG         +    T           + PP +        V+  Q     C+ 
Sbjct: 569  TARNAAGSTSVAFRVEIHTVPT---------IRSGPPAVN-------VSVNQTALLPCQA 612

Query: 4647 VGKPLPTVQWYKGDKLIKP-SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             G P P V W K    + P S  F++     E +LRI     +D G Y C+A NSAG   
Sbjct: 613  DGVPAPLVSWRKDRVPLDPRSPRFEI---LPEGSLRIQPVLAQDAGHYLCLASNSAGSDR 669

Query: 4706 VAAKLKVTQ--PDQADNLPALTPLRDIVVY--EGQPAQFKTQ 4743
                L+V    P +A   P     + +VV+  +GQ   F+ Q
Sbjct: 670  QGRDLRVLALLPCEASGSP-----KPLVVWWKDGQKLDFRLQ 706



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 54/166 (32%), Positives = 71/166 (42%), Gaps = 11/166 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  TG P P V+W     Q+         V+ SG  AL I       +G  TC ARN +G
Sbjct: 775 CHSTGIPAPTVSWSKAGAQL-GARGSGYRVSPSG--ALEIGQALPIHAGRYTCSARNSAG 831

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
             A +     ++   VV P      S +     E V+L   A G P P ITWQK+G+ + 
Sbjct: 832 -VAHKHVFLTVQASPVVKPLP----SVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVA 886

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
                ++   G    L I  A   DA  Y C A+N AGS   + RL
Sbjct: 887 TGVSTQVLPGG---QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRL 929



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 54/170 (31%), Positives = 77/170 (45%), Gaps = 14/170 (8%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            GD    I W  +G  +  SH +R     G   L I  T+  D+G Y C A N+ G A+  
Sbjct: 1141 GDPVPDIHWIKDGLPLRGSH-LRHQLQNGS--LTIHRTERDDAGRYQCLAENEMGVAKKV 1197

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
            V L  V +S    P F    Q++  ++ G      C      +P   IEW   GQP+R S
Sbjct: 1198 VIL--VLQSA---PVFQVEPQDMT-VRSGDDVALRCQAT--GEPTPTIEWLQAGQPLRAS 1249

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKG 3245
             R++T+ D G + L+    +  D+G Y C A+N  G    RA +   G G
Sbjct: 1250 RRLRTLPD-GSLWLE--NVETGDAGTYDCVAHNLLGSATARAFLVVRGMG 1296



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 35/98 (35%), Positives = 47/98 (47%), Gaps = 6/98 (6%)

Query: 263 VSPPKIAQ--KPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
           + PP I    +P    L  GA  +      G P+P +TW K+GQ L     +   T    
Sbjct: 402 MEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR--- 458

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             LRV N Q  D+G YT LAE+P G I  S  + V++P
Sbjct: 459 -VLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAP 495



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 38/124 (30%), Positives = 62/124 (50%), Gaps = 9/124 (7%)

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508
           +L +  V   DSG  +CVA +++GE     +L V+E   +   +   + + L++  G P+
Sbjct: 368 SLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHI---EDSGQPTELSLTPGAPM 424

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS-TLDIPRAKASDAAWYQCTAQN 567
            L   A GTP P ITW KDG  +      R+  +  A+  L +   +  DA  Y C A++
Sbjct: 425 ELLCDAQGTPQPNITWHKDGQAL-----TRLENNSRATRVLRVENVQVRDAGLYTCLAES 479

Query: 568 VAGS 571
            AG+
Sbjct: 480 PAGA 483



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V+  APVF +  +D+ V          +    G+P   +EWL+ G P+ AS RL T+ D 
Sbjct: 1201 VLQSAPVFQVEPQDMTVRSGDDVALRCQA--TGEPTPTIEWLQAGQPLRASRRLRTLPD- 1257

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA--SLQLESQHESAL 1818
               +L ++ V   D+GTY C A N LG A   + L V+      L L  Q +  L
Sbjct: 1258 --GSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGMGHPCLDLRGQRQDLL 1310



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 36/119 (30%), Positives = 54/119 (45%), Gaps = 8/119 (6%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE-RFSTLNVREGEPV 508
           L I    +SD G+ +C   N +GE      L V      V P F   +  T++   G P+
Sbjct: 1   LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV-----QVPPTFENPKTETVSQVAGSPL 55

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           VL     G P P +TW KD +P+  +    + + GG   L + R + + A  Y C A+N
Sbjct: 56  VLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGG--RLQLSRLQPAQAGTYTCVAEN 112



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 10/159 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  +G P P V W+  D Q  D    +       ++AL++T     DS    CV  N+ G
Sbjct: 682 CEASGSPKPLVVWW-KDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVG 740

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI- 531
           E     ++ V      V P   +  +   V    PVVL   + G P P ++W K G  + 
Sbjct: 741 EAHRLYQVTVH-----VPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLG 795

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                 R+   G    L+I +A    A  Y C+A+N AG
Sbjct: 796 ARGSGYRVSPSG---ALEIGQALPIHAGRYTCSARNSAG 831



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 26/70 (37%), Positives = 41/70 (58%), Gaps = 3/70 (4%)

Query: 932  RLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            R +  G+ T  +EWL+ G+P+ AS R+ T  +    +L +++V   DAG Y C A+N +G
Sbjct: 1226 RCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---SLWLENVETGDAGTYDCVAHNLLG 1282

Query: 992  QATTSANLTI 1001
             AT  A L +
Sbjct: 1283 SATARAFLVV 1292



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 6/89 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F VE +D + V  G  V   C+    G+PT  I+W   G+P     R+ TL D    +
Sbjct: 1206 PVFQVEPQD-MTVRSGDDVALRCQA--TGEPTPTIEWLQAGQPLRASRRLRTLPDG---S 1259

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTA 3783
            L ++ +   DAG Y C A N  GSAT  A
Sbjct: 1260 LWLENVETGDAGTYDCVAHNLLGSATARA 1288



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 36/102 (35%), Positives = 48/102 (47%), Gaps = 6/102 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PVF      +  ++ GD     C+     +P  TI+W   GQ +RA  R RT  D G + 
Sbjct: 1206 PVFQVEPQDM-TVRSGDDVALRCQAT--GEPTPTIEWLQAGQPLRASRRLRTLPD-GSLW 1261

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILD 2210
            L+ + T   D+GTY C A N LG A     L V G  +  LD
Sbjct: 1262 LENVET--GDAGTYDCVAHNLLGSATARAFLVVRGMGHPCLD 1301



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 7/134 (5%)

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
            +L++      D G Y CVA + AG      +L V +P   ++    T L    +  G P 
Sbjct: 368  SLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELS---LTPGAPM 424

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
            +         +P I W ++G  +    +    +     VL + N    D G +TC A + 
Sbjct: 425  ELLCDAQGTPQPNITWHKDGQALTRLEN----NSRATRVLRVENVQVRDAGLYTCLAESP 480

Query: 4799 AGQVETSAKLVVKS 4812
            AG +E S ++ V++
Sbjct: 481  AGAIEKSFRVRVQA 494



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 6/92 (6%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECN-KYSMRYNEQTGDV 129
            PP+ E    +    +G +A    K RG+P P ++W +   P+     K+++   + +G+ 
Sbjct: 934  PPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI---QPSGE- 989

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             LL+K +   D G YTCTA N  G A   V++
Sbjct: 990  -LLVKNLEGQDAGTYTCTAENAVGRARRRVHL 1020



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 59/249 (23%), Positives = 87/249 (34%), Gaps = 15/249 (6%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G P P VSW++  A L         Y       +L I Q  P   G YTC+ARN  G A 
Sbjct: 779  GIPAPTVSWSKAGAQL---GARGSGYRVSPSG-ALEIGQALPIHAGRYTCSARNSAGVAH 834

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
              V++  +                     +  +A G    T    ++   VA    T   
Sbjct: 835  KHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVL 894

Query: 217  STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK 276
                 ++    +    +      I K   G +  +    +        PP I     +  
Sbjct: 895  PGGQLRI---AHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ------VPPVIENGLPDLS 945

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
              EG+ A    +  G+P P +TW K+GQ +  S      T      L V+N +  D+G Y
Sbjct: 946  TTEGSHAFLPCKARGSPEPNITWDKDGQPV--SGAEGKFTIQPSGELLVKNLEGQDAGTY 1003

Query: 337  TLLAENPNG 345
            T  AEN  G
Sbjct: 1004 TCTAENAVG 1012



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 5/94 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   P D+ +         C+     + +  +EW   G+PL    R++T+ D G + L
Sbjct: 1206 PVFQVEPQDMTVRSGDDVALRCQA--TGEPTPTIEWLQAGQPLRASRRLRTLPD-GSLWL 1262

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            E   V   DAG Y C A N  G AT    L V+G
Sbjct: 1263 E--NVETGDAGTYDCVAHNLLGSATARAFLVVRG 1294



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            +S  EG  A    +    G     + W KDG+PV  +    T    G   L +K++   D
Sbjct: 944  LSTTEGSHAFLPCKAR--GSPEPNITWDKDGQPVSGAEGKFTIQPSG--ELLVKNLEGQD 999

Query: 979  AGHYTCRAYNAIGQATTSANLTIV 1002
            AG YTC A NA+G+A    +LTI+
Sbjct: 1000 AGTYTCTAENAVGRARRRVHLTIL 1023



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 6/96 (6%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APVF V   ++  +R G++     R   T +P   +EW   G+ L+A  R RT  D G +
Sbjct: 1205 APVFQVEPQDM-TVRSGDDVAL--RCQATGEPTPTIEWLQAGQPLRASRRLRTLPD-GSL 1260

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
             LE   T   D+G Y C A+N  G A   A + V+G
Sbjct: 1261 WLENVET--GDAGTYDCVAHNLLGSATARAFLVVRG 1294



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 29/87 (33%), Positives = 45/87 (51%), Gaps = 6/87 (6%)

Query: 2917 IAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQ--GSRFKLTSDFGFVTLDLV 2974
            +A EH ++EGQ + L+ + + +  PD  + W  +G  L Q  G   +   D G  +L L 
Sbjct: 136  VAREHHVLEGQEVRLDCEADGQPPPD--VAWLKDGSPLGQDMGPHLRFYLDGG--SLVLK 191

Query: 2975 DVYERDSGIYTCKAYNKRGEAFTSSTV 3001
             ++  D+G YTC A+N  GE     TV
Sbjct: 192  GLWASDAGAYTCVAHNPAGEDARLHTV 218



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 45/173 (26%), Positives = 68/173 (39%), Gaps = 14/173 (8%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            D+S  + +H        G     I W  +G+ +  +    T+   G ++++ L  +  D+
Sbjct: 943  DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNL--EGQDA 1000

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            GTY+C A N  G+A   V L  +       P FTT +     L+ G      C       
Sbjct: 1001 GTYTCTAENAVGRARRRVHLTIL-----VLPVFTT-LPGDRSLRLGDRLWLRCAA--RGS 1052

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P  +I W  N +P+            G   L  A     DSG YVC A N+ G
Sbjct: 1053 PTPRIGWTVNDRPVTEGVS----EQDGGSTLQRAAVSREDSGTYVCWAENRVG 1101



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 3/76 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   + W+++G+P+  S+     H     +L +     +D+G Y C A NE+G A   
Sbjct: 1141 GDPVPDIHWIKDGLPLRGSH---LRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKV 1197

Query: 1798 STLFVQSKASLQLESQ 1813
              L +QS    Q+E Q
Sbjct: 1198 VILVLQSAPVFQVEPQ 1213



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 41/160 (25%), Positives = 67/160 (41%), Gaps = 8/160 (5%)

Query: 1784 TCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQA 1843
            +CR + + GE + S +L  +   SLQLE+           +  S   + R   ++ V + 
Sbjct: 348  SCRGMKD-GEPLLSQSL--EQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEP 404

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P  I     PT+LS    A  E   +    P   + W+ +G+ L        +N      
Sbjct: 405  PH-IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR----LENNSRATRV 459

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            L +  V   D+G YTC A +  G    S R+ VQ+  +I+
Sbjct: 460  LRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIV 499



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 88/384 (22%), Positives = 141/384 (36%), Gaps = 46/384 (11%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            ++   EG      C+    G P   I W  +G+P +      T+   G   L +  +  +
Sbjct: 943  DLSTTEGSHAFLPCKAR--GSPEPNITWDKDGQPVSGAEGKFTIQPSG--ELLVKNLEGQ 998

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS---GEKIKELERGRISDAP 3820
            DAG YTC A N  G A     +T      + + + LP   S   G+++      R S  P
Sbjct: 999  DAGTYTCTAENAVGRARRRVHLTILV---LPVFTTLPGDRSLRLGDRLWLRCAARGSPTP 1055

Query: 3821 KEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            +    V+  P  +T+  S   E+  G   +     +ED    + W  N        R   
Sbjct: 1056 RIGWTVNDRP--VTEGVS---EQDGGSTLQRAAVSREDSGTYVCWAEN--------RVGR 1102

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI-ILQNQVP-RGMK 3938
               + FV +    V   ++  Y+   V   G       +    +PDI  +++ +P RG  
Sbjct: 1103 TQAVSFVHVKEAPVLQGEAFSYLVEPVG--GSIQLDCVVRGDPVPDIHWIKDGLPLRGSH 1160

Query: 3939 RSEALTQMEATIKKYTSE-----VYLTEDDLYDVDK------KQPPRFVTQIQSQTSLVE 3987
                L     TI +   +       L E+++    K      +  P F  + Q  T +  
Sbjct: 1161 LRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMT-VRS 1219

Query: 3988 METTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYL 4047
             +     CQ    G+P   +EW   G+PL    R   + D      N   V   D+G Y 
Sbjct: 1220 GDDVALRCQ--ATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLEN---VETGDAGTYD 1274

Query: 4048 CRATNLYGMDETKA--VIKTTGKP 4069
            C A NL G    +A  V++  G P
Sbjct: 1275 CVAHNLLGSATARAFLVVRGMGHP 1298



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 5/98 (5%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + +  AP F     ++    G +V L C  Q  G+ T  +EW   G+P++   R R   +
Sbjct: 1200 LVLQSAPVFQVEPQDMTVRSGDDVALRC--QATGEPTPTIEWLQAGQPLRASRRLRTLPD 1257

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                +L L +V   D+G Y C A N LG A     L V
Sbjct: 1258 ---GSLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            S P    +P++  ++ G D   + Q +G P P + W + GQ L  S +   + T    +L
Sbjct: 1204 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRR---LRTLPDGSL 1260

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
             + N +  D+G Y  +A N  G      +L V
Sbjct: 1261 WLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 39/170 (22%), Positives = 60/170 (35%), Gaps = 9/170 (5%)

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C+  G P P V W+K  + +         R      L ++   P+D   ++CV  N  G 
Sbjct: 682  CEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGE 741

Query: 4704 VTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
                 ++ V   P  AD+        D  V    P       T    PT+ W + GA + 
Sbjct: 742  AHRLYQVTVHVPPTIADDQT------DFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLG 795

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
                   +    +  L IG       G +TC A  +AG       L V++
Sbjct: 796  ARGSGYRVSP--SGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQA 843



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P + V WL++G+P+  S R T +H  G+  L +  V   D+G +TC A +  G A  +
Sbjct: 252  GSPPIHVSWLKDGLPLPLSQR-TLLHGSGH-TLRISKVQLADAGIFTCVAASPAGVADRN 309

Query: 1798 STL 1800
             TL
Sbjct: 310  FTL 312



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 8/107 (7%)

Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIEN-VIEGQHVHFECKLEPVTDSNLKVEWFKN 1483
            E+T    + D +  +V + PR  +   + E+ V+EGQ V  +C+ +     +  V W K+
Sbjct: 111  ENTQAEARKDFV-VAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPD--VAWLKD 167

Query: 1484 GQPV--TIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
            G P+   +G   R   D G + L    L A D+G YTC A N  G D
Sbjct: 168  GSPLGQDMGPHLRFYLDGGSLVLK--GLWASDAGAYTCVAHNPAGED 212



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 5/96 (5%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            S P+F+   ++     G +     +  G PTP + W +   PL      + R      D 
Sbjct: 1204 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL-----RASRRLRTLPDG 1258

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
            SL ++ +  GD G Y C A N  G A    ++   G
Sbjct: 1259 SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRG 1294



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 5/92 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F V  + +T   G  +    R +  G+PT  IEWL+ GQ + AS R  ++   G  SL
Sbjct: 1206 PVFQVEPQDMTVRSGDDVAL--RCQATGEPTPTIEWLQAGQPLRASRRLRTL-PDG--SL 1260

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             + ++   D+G Y C A +  G A  +A L V
Sbjct: 1261 WLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 14/169 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            +G  +  + W  +   +E+S     V   G + L  L  +   +GTY+C A N   +A  
Sbjct: 62   SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRL--QPAQAGTYTCVAENTQAEARK 119

Query: 3135 SVKLECVDKSKGQKPRF-TTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
               +  +       PR  ++ +     + +GQ    +C       PD  + W  +G P+ 
Sbjct: 120  DFVVAVL-----VAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPD--VAWLKDGSPLG 172

Query: 3194 HST--RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
                  ++   D G +VL   +    D+G Y C A+N  GED    T+N
Sbjct: 173  QDMGPHLRFYLDGGSLVLKGLWAS--DAGAYTCVAHNPAGEDARLHTVN 219



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 14/128 (10%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEIS--VKLECVDKSKGQK-PRFTTHIQNIEGLKD 3163
            VL +   +  D+G Y+C A +  G  E S  V+++      G + PRF      + GL  
Sbjct: 459  VLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRF------VVGLAP 512

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            GQ    EC+V    +P  KI W+ +G  ++     +      F+ L    T   DSG+Y 
Sbjct: 513  GQLV-LECSVEA--EPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA--DSGDYS 567

Query: 3224 CRAYNKYG 3231
            C A N  G
Sbjct: 568  CTARNAAG 575



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V+   PV    + D+   E   A    +    G P+  + W ++G P+  +    T+   
Sbjct: 930  VVQVPPVIENGLPDLSTTEGSHAFLPCKAR--GSPEPNITWDKDGQPVSGAEGKFTIQPS 987

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEA 1794
            G   L +K +  +D+GTYTC A N +G A
Sbjct: 988  G--ELLVKNLEGQDAGTYTCTAENAVGRA 1014



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 5/89 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++AP+      SY     G  + L+  V  R DP   I W K+G+ L  G+ L+     
Sbjct: 1111 VKEAPVLQGEAFSYLVEPVGGSIQLDCVV--RGDPVPDIHWIKDGLPLR-GSHLRHQLQN 1167

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            G  +L+I+    DD+G Y C A N +G A
Sbjct: 1168 G--SLTIHRTERDDAGRYQCLAENEMGVA 1194



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 8/98 (8%)

Query: 2638 VQQAPIFTTHLKSYDKLVE-GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            +Q AP+F   ++  D  V  G  V L  Q      P   IEW + G  L    RL++  D
Sbjct: 1202 LQSAPVF--QVEPQDMTVRSGDDVALRCQATGEPTPT--IEWLQAGQPLRASRRLRTLPD 1257

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                +L + ++   D+G Y C A NLLG A + A + +
Sbjct: 1258 G---SLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            TG+ +  IEW   G+ + AS R+RT+   G + LE    +T D+GTY C A N  G A
Sbjct: 1230 TGEPTPTIEWLQAGQPLRASRRLRTL-PDGSLWLE--NVETGDAGTYDCVAHNLLGSA 1284



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 5/89 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            VQ  P+    L       EG H +L  +     +PN  I W K+G  ++ GA  K T   
Sbjct: 931  VQVPPVIENGLPDLST-TEGSHAFLPCKARGSPEPN--ITWDKDGQPVS-GAEGKFTIQP 986

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
                L + +L   D+G YTC A N +G A
Sbjct: 987  S-GELLVKNLEGQDAGTYTCTAENAVGRA 1014



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 4/92 (4%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F    QD  V  G      C+ TG P P + W    + +R     + L + S    L
Sbjct: 1205 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS----L 1260

Query: 451  MITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             + NV   D+G   CVA N  G    +  L V
Sbjct: 1261 WLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           +G   + + +  G P P V+W +  +PL +     +R+    G  SL++K +   D G Y
Sbjct: 144 EGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG--SLVLKGLWASDAGAY 201

Query: 145 TCTARNQYGE 154
           TC A N  GE
Sbjct: 202 TCVAHNPAGE 211



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 10/128 (7%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G   L+       DSGTY C A N+ G+ +    +   +    Q   F+  ++ +     
Sbjct: 1075 GGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPV----- 1129

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G S   +C V    DP   I W  +G P+R S  ++     G   L I  T+  D+G Y 
Sbjct: 1130 GGSIQLDCVV--RGDPVPDIHWIKDGLPLRGS-HLRHQLQNG--SLTIHRTERDDAGRYQ 1184

Query: 3224 CRAYNKYG 3231
            C A N+ G
Sbjct: 1185 CLAENEMG 1192



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 5/88 (5%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSN-KHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            G   Q    + G+P P + W K+G  L  S+ +H++     + +L +  T++ D+G Y  
Sbjct: 1130 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQL----QNGSLTIHRTERDDAGRYQC 1185

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQ 366
            LAEN  G       L ++S     V+ Q
Sbjct: 1186 LAENEMGVAKKVVILVLQSAPVFQVEPQ 1213



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 8/99 (8%)

Query: 1172 ISKSKPVF-VQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY 1230
            + +S PVF V+P      V  G ++ L C  +  G+PT  +EW   G+ +    R +T  
Sbjct: 1201 VLQSAPVFQVEP--QDMTVRSGDDVALRC--QATGEPTPTIEWLQAGQPLRASRRLRTLP 1256

Query: 1231 DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            D G + L+  +  + D G Y   A N LGSA   A + V
Sbjct: 1257 D-GSLWLE--NVETGDAGTYDCVAHNLLGSATARAFLVV 1292



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF     ++  + GD++   C  + + +PT  IEW    +PL +  R ++  D S   L 
Sbjct: 1207 VFQVEPQDMTVRSGDDVALRC--QATGEPTPTIEWLQAGQPLRASRRLRTLPDGS---LW 1261

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            + +    D+G Y C A N  GSAT    L   G
Sbjct: 1262 LENVETGDAGTYDCVAHNLLGSATARAFLVVRG 1294



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 8/107 (7%)

Query: 626 PPGEEDRVYPPPQFIVPLKSVTAMEGGKI-----HFETRIEPV-GDPTMKIEWLKNGQSI 679
           P GE+ R++     + P     A   G +        T + PV G P + + WLK+G  +
Sbjct: 208 PAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPL 267

Query: 680 EASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVL 726
             S R T +   G+ +L +  + + D+G +TC A S  GVA+    L
Sbjct: 268 PLSQR-TLLHGSGH-TLRISKVQLADAGIFTCVAASPAGVADRNFTL 312



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 12/105 (11%)

Query: 632 RVYPPPQFIVPL--KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIE--ASSRFTS 687
           RV  PP  + P   + V  +  G++  E  +E   +P  KI W ++G  ++  A ++F  
Sbjct: 491 RVQAPPNIVGPRGPRFVVGLAPGQLVLECSVE--AEPAPKITWHRDGIVLQEDAHTQFPE 548

Query: 688 IFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTP 730
             RF    L + +L+  DSG+Y+C A +A G      +  +H  P
Sbjct: 549 RGRF----LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVP 589



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 8/104 (7%)

Query: 1842 QAPRFITQLNGP---TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND 1898
            QAP  I    GP     L+ GQ    EC +E  P P  ++ W+ +G VLQ     +    
Sbjct: 493  QAPPNIVGPRGPRFVVGLAPGQLV-LECSVEAEPAP--KITWHRDGIVLQEDAHTQFPER 549

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              F  L  L+    DSG+Y+C A N  G    + R+ + +  +I
Sbjct: 550  GRFLQLQALST--ADSGDYSCTARNAAGSTSVAFRVEIHTVPTI 591



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EG H    CK     + N  + W K+GQPV+       I   G   L + +L  +D+G Y
Sbjct: 948  EGSHAFLPCKARGSPEPN--ITWDKDGQPVSGAEGKFTIQPSG--ELLVKNLEGQDAGTY 1003

Query: 1518 TCRAVNLVGTDEVSCRLT 1535
            TC A N VG       LT
Sbjct: 1004 TCTAENAVGRARRRVHLT 1021



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 6/93 (6%)

Query: 3837 KSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS--GHRYRTVYDMGFVSLDILYV 3894
            + H V E + VR +C  + +  P   + W ++G  L    G   R   D G  SL +  +
Sbjct: 138  REHHVLEGQEVRLDCEADGQPPPD--VAWLKDGSPLGQDMGPHLRFYLDGG--SLVLKGL 193

Query: 3895 YAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            +A D+G Y C A N  GED    T++    P I
Sbjct: 194  WASDAGAYTCVAHNPAGEDARLHTVNVLVPPTI 226



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 7/114 (6%)

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQ-LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            ++++ + R+D  VAV  APR  +  +     + EGQ    +C  +  P P+  V W  +G
Sbjct: 111  ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPD--VAWLKDG 168

Query: 1885 KVL--QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
              L    G   R   D G  +L +  ++  D+G YTC A N  G+      +NV
Sbjct: 169  SPLGQDMGPHLRFYLDGG--SLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNV 220



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 10/100 (10%)

Query: 1300 QVRED--ITVMQAPQF--SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
            + R+D  + V+ AP+   S        +EG  V L+C     G     V W  +G P+  
Sbjct: 116  EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEAD--GQPPPDVAWLKDGSPL-- 171

Query: 1356 GHRFRPAYEF--DYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            G    P   F  D  +L L  ++  D+G YTC A N  GE
Sbjct: 172  GQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGE 211



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 6/88 (6%)

Query: 1851 NGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILT 1908
            NG   LS  EG  A   C+    P+PN  + W  +G+ +       T    G   L +  
Sbjct: 939  NGLPDLSTTEGSHAFLPCKARGSPEPN--ITWDKDGQPVSGAEGKFTIQPSG--ELLVKN 994

Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            + G+D+G YTC A N +G+A   + L +
Sbjct: 995  LEGQDAGTYTCTAENAVGRARRRVHLTI 1022



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            PT R+ W  N RPV +G     +   G   L       ED+GTY+C A N VG     S 
Sbjct: 1053 PTPRIGWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSF 1108

Query: 2067 VKV 2069
            V V
Sbjct: 1109 VHV 1111



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 6/103 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F    QD+  ++ G +     Q T   +PT  +EW + G+P+ AS R+ ++ +    S
Sbjct: 1206 PVFQVEPQDM-TVRSGDDVALRCQAT--GEPTPTIEWLQAGQPLRASRRLRTLPD---GS 1259

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADL 872
            L + ++   DAG+Y   A N LG A + A + V        DL
Sbjct: 1260 LWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGMGHPCLDL 1302



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/73 (28%), Positives = 33/73 (45%)

Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
           R   + EG + +   +  G P P V W K+G  L       +    +  +L ++    SD
Sbjct: 138 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASD 197

Query: 333 SGHYTLLAENPNG 345
           +G YT +A NP G
Sbjct: 198 AGAYTCVAHNPAG 210



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
           G   + V WLKDG P+  S R T     G+  L I  V + DAG +TC A +  G A  +
Sbjct: 252 GSPPIHVSWLKDGLPLPLSQR-TLLHGSGH-TLRISKVQLADAGIFTCVAASPAGVADRN 309

Query: 997 ANL 999
             L
Sbjct: 310 FTL 312



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 5/70 (7%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            GG+ + +  +RG+P P + W +   PL       +R+  Q G  SL I +    D G Y 
Sbjct: 1130 GGSIQLDCVVRGDPVPDIHWIKDGLPL---RGSHLRHQLQNG--SLTIHRTERDDAGRYQ 1184

Query: 146  CTARNQYGEA 155
            C A N+ G A
Sbjct: 1185 CLAENEMGVA 1194



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSINSLRNDD 2711
            ++EGQ V L+ + + +  P+  + W K+G  L    G  L+   D G  +L +  L   D
Sbjct: 142  VLEGQEVRLDCEADGQPPPD--VAWLKDGSPLGQDMGPHLRFYLDGG--SLVLKGLWASD 197

Query: 2712 SGIYTCKATNLLGEAVSTASIKI 2734
            +G YTC A N  GE     ++ +
Sbjct: 198  AGAYTCVAHNPAGEDARLHTVNV 220



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 3/71 (4%)

Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
           + SG PRP +TW K G  +      +++       LR+ +    D+G+Y  +A+N  G  
Sbjct: 867 EASGIPRPTITWQKEGLNVATGVSTQVLPGGQ---LRIAHASPEDAGNYLCIAKNSAGSA 923

Query: 348 VTSGYLAVESP 358
           +    L V+ P
Sbjct: 924 MGKTRLVVQVP 934



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 8/93 (8%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+F  +  +     G         RG+PTP + WT    P+ E        +EQ G  +L
Sbjct: 1026 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTE------GVSEQDGGSTL 1079

Query: 132  LIKQIGPGDEGEYTCTARNQYG--EAICSVYIQ 162
                +   D G Y C A N+ G  +A+  V+++
Sbjct: 1080 QRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 1112



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/118 (25%), Positives = 51/118 (43%), Gaps = 7/118 (5%)

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRL 1334
            +V + + + A       E+A  R ++ R  +T++  P F+    +     G  + L C  
Sbjct: 991  LVKNLEGQDAGTYTCTAENAVGRARR-RVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAA 1049

Query: 1335 QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            +  G  T R+ W  N +P+  G   +         L   +V  EDSG Y C A N++G
Sbjct: 1050 R--GSPTPRIGWTVNDRPVTEGVSEQDGGS----TLQRAAVSREDSGTYVCWAENRVG 1101



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 4/82 (4%)

Query: 263 VSPPKIAQKPRNSKLQE--GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
           V  P   + P+   + +  G+       +SG P P VTW K+   + +S  H +++    
Sbjct: 33  VQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR 92

Query: 321 TTLRVRNTQKSDSGHYTLLAEN 342
             L++   Q + +G YT +AEN
Sbjct: 93  --LQLSRLQPAQAGTYTCVAEN 112



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 930 EARL--EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAY 987
           E RL  E  G     V WLKDG P+         F     +L +K +   DAG YTC A+
Sbjct: 147 EVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAH 206

Query: 988 NAIGQ 992
           N  G+
Sbjct: 207 NPAGE 211



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 6/88 (6%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V +  PVF    Q++  ++ G      C+    G+PT  +EW +  + +  S R+    D
Sbjct: 1201 VLQSAPVFQVEPQDM-TVRSGDDVALRCQA--TGEPTPTIEWLQAGQPLRASRRLRTLPD 1257

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                S+ + +V   D G Y C A NLLG
Sbjct: 1258 G---SLWLENVETGDAGTYDCVAHNLLG 1282



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 4/83 (4%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +V + G+ +   C V  S  P + + W  +  PLP   R    H   + +L I+     D
Sbjct: 236  LVSRPGELVTMVCPVRGS--PPIHVSWLKDGLPLPLSQR-TLLHGSGH-TLRISKVQLAD 291

Query: 2843 SGIYTCKATNSKGSATTSGSLRC 2865
            +GI+TC A +  G A  + +L+C
Sbjct: 292  AGIFTCVAASPAGVADRNFTLQC 314



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 2/76 (2%)

Query: 779  LGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAE 838
            L +L     +H          P   + W KDG+P++ +    +I   G   L + +L  +
Sbjct: 941  LPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG--ELLVKNLEGQ 998

Query: 839  DAGSYTVRAVNKLGEA 854
            DAG+YT  A N +G A
Sbjct: 999  DAGTYTCTAENAVGRA 1014



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/104 (31%), Positives = 42/104 (40%), Gaps = 9/104 (8%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            R  V + +   P F T L G   L  G      C     P P  R+ W  N + +  G  
Sbjct: 1015 RRRVHLTILVLPVFTT-LPGDRSLRLGDRLWLRCAARGSPTP--RIGWTVNDRPVTEG-- 1069

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG--QAVSSIRL 1934
               S   G + L    V  EDSG Y C A N +G  QAVS + +
Sbjct: 1070 --VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHV 1111



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 7/103 (6%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P+FTT L     L  G  ++L      R  P  +I W  N   +T G    S  D G  T
Sbjct: 1026 PVFTT-LPGDRSLRLGDRLWLRCAA--RGSPTPRIGWTVNDRPVTEGV---SEQDGGS-T 1078

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
            L   ++  +DSG Y C A N +G   + + + +++   L GE+
Sbjct: 1079 LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEA 1121



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 6/94 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F   P+ +  V  G  V   C  +   +    +EW + GQP+    R R + D G + 
Sbjct: 1206 PVFQVEPQDM-TVRSGDDVALRC--QATGEPTPTIEWLQAGQPLRASRRLRTLPD-GSLW 1261

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            L+ ++    D+G Y C A NL+G+      L  R
Sbjct: 1262 LENVE--TGDAGTYDCVAHNLLGSATARAFLVVR 1293



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F    ++  V  G  V L    T   +PT  +EW   G+P++   R +T  D G + L
Sbjct: 1206 PVFQVEPQDMTVRSGDDVALRCQAT--GEPTPTIEWLQAGQPLRASRRLRTLPD-GSLWL 1262

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +       D GTY C A N +G A   + + V
Sbjct: 1263 E--NVETGDAGTYDCVAHNLLGSATARAFLVV 1292



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/53 (33%), Positives = 24/53 (45%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PVF   P  +TV  G+     C+ TG P P + WL  G  +    R +   DG
Sbjct: 1206 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG 1258



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 3707 VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAG 3766
            V EG  V  DC  +  G P   + W  +G P       H        +L +  ++A DAG
Sbjct: 142  VLEGQEVRLDCEAD--GQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAG 199

Query: 3767 EYTCRATNKWG 3777
             YTC A N  G
Sbjct: 200  AYTCVAHNPAG 210



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 10/93 (10%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH---RFRP 1361
            + V   P     L ++ T EG++  L C+ +  G     + W  +G+P+         +P
Sbjct: 929  LVVQVPPVIENGLPDLSTTEGSHAFLPCKAR--GSPEPNITWDKDGQPVSGAEGKFTIQP 986

Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEA 1394
            + E     L + ++  +D+G YTC A N +G A
Sbjct: 987  SGE-----LLVKNLEGQDAGTYTCTAENAVGRA 1014



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 6/131 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL +         + Q L ++     ++ V + +  AP F  +    T  S G      C
Sbjct: 1169 SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRS-GDDVALRC 1227

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
            +    P P   +EW   G+ L++  R RT  D    +L +  V   D+G Y C A N LG
Sbjct: 1228 QATGEPTPT--IEWLQAGQPLRASRRLRTLPD---GSLWLENVETGDAGTYDCVAHNLLG 1282

Query: 1927 QAVSSIRLNVQ 1937
             A +   L V+
Sbjct: 1283 SATARAFLVVR 1293



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 9/147 (6%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
            I R+ +++AG  + Q L +        +V  V   AP+     +++ ++ G       R 
Sbjct: 1172 IHRTERDDAG--RYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVAL--RC 1227

Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
                + T  +EW    +PL++ SR   T   G + L+ +     D+GTY C A N LG A
Sbjct: 1228 QATGEPTPTIEWLQAGQPLRA-SRRLRTLPDGSLWLENVET--GDAGTYDCVAHNLLGSA 1284

Query: 1662 VTSGIAIVH--SKKSIYLESQHEGALP 1686
                  +V       + L  Q +  LP
Sbjct: 1285 TARAFLVVRGMGHPCLDLRGQRQDLLP 1311



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PV    L  L    EG  A   C+     +P++T  W  +GQ +       T    G + 
Sbjct: 935  PVIENGLPDLSTT-EGSHAFLPCKARGSPEPNIT--WDKDGQPVSGAEGKFTIQPSGELL 991

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEA 2193
            +  L    +D+GTY C A N +G A
Sbjct: 992  VKNLE--GQDAGTYTCTAENAVGRA 1014



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 47/197 (23%), Positives = 74/197 (37%), Gaps = 22/197 (11%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   + +D G YSC+ +N  G+A  +  L        + P+  T  Q       G   
Sbjct: 1    LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQ-----VAGSPL 55

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C V  V  P   + W  +  P+  S     VS  G   L ++  Q   +G Y C A 
Sbjct: 56   VLTCDVSGVPAP--TVTWLKDRMPVESSAVHGVVSRGG--RLQLSRLQPAQAGTYTCVAE 111

Query: 3228 NKYGE---DFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
            N   E   DF  A +            ++   +A  RE   L+G + +       +PP  
Sbjct: 112  NTQAEARKDFVVAVL--------VAPRIRSSGVA--REHHVLEGQEVRLDCEADGQPPPD 161

Query: 3285 ITQIQDVTKLVEGQSAH 3301
            +  ++D + L +    H
Sbjct: 162  VAWLKDGSPLGQDMGPH 178



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 633  VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
            V  PP     L  ++  EG       +    G P   I W K+GQ +  +    +I   G
Sbjct: 931  VQVPPVIENGLPDLSTTEGSHAFLPCKAR--GSPEPNITWDKDGQPVSGAEGKFTIQPSG 988

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
               L + +L  QD+G YTC A +A G A  +  L +
Sbjct: 989  --ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 1022



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 8/103 (7%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P+ TT   +  ++ G R     R       T ++ W  N++P+  G     +   G   L
Sbjct: 1026 PVFTTLPGDRSLRLGDRLWL--RCAARGSPTPRIGWTVNDRPVTEGV----SEQDGGSTL 1079

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQ 1680
               +   EDSGTY C A N +G   T  ++ VH K++  L+ +
Sbjct: 1080 QRAAVSREDSGTYVCWAENRVGR--TQAVSFVHVKEAPVLQGE 1120



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 9/96 (9%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PVF T L    +L+ GDR    C       P   I W  N + +  G     +   G   
Sbjct: 1026 PVF-TTLPGDRSLRLGDRLWLRCAAR--GSPTPRIGWTVNDRPVTEG----VSEQDGGST 1078

Query: 2169 LDILYTYAEDSGTYMCKATNKLG--EAVNTCTLKVA 2202
            L       EDSGTY+C A N++G  +AV+   +K A
Sbjct: 1079 LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEA 1114



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 10/124 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L++      DSGTYSC A ++ G+A    +L  ++    +     T +     L  G   
Sbjct: 369  LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTEL----SLTPGAPM 424

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C       P+  I W+ +GQ +   TR++  S     VL +   Q  D+G Y C A 
Sbjct: 425  ELLCDAQGTPQPN--ITWHKDGQAL---TRLENNSR-ATRVLRVENVQVRDAGLYTCLAE 478

Query: 3228 NKYG 3231
            +  G
Sbjct: 479  SPAG 482



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 3/66 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P+  + W + G+ + A+   T +   G   L + + +PED+G Y C A N  G A+  
Sbjct: 870  GIPRPTITWQKEGLNV-ATGVSTQVLPGGQ--LRIAHASPEDAGNYLCIAKNSAGSAMGK 926

Query: 1798 STLFVQ 1803
            + L VQ
Sbjct: 927  TRLVVQ 932



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 10/104 (9%)

Query: 1711 PVFT-MPM-KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            PVFT +P  + +R+ +       AR    G P  R+ W  N  P+            G  
Sbjct: 1026 PVFTTLPGDRSLRLGDRLWLRCAAR----GSPTPRIGWTVNDRPVTEG----VSEQDGGS 1077

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
             L    V+ EDSGTY C A N +G     S + V+    LQ E+
Sbjct: 1078 TLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEA 1121



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 40/169 (23%), Positives = 67/169 (39%), Gaps = 13/169 (7%)

Query: 3628 GLYTCKATN--RHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEI 3685
            G + C +    + GE  +S  L+    QG  L+ +      SGT S   + E    R   
Sbjct: 342  GAFPCLSCRGMKDGEPLLSQSLE----QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF 397

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
             +   +P P          + +  G P+   C  +  G P   I W  +G+     +R+ 
Sbjct: 398  QLTVMEP-PHIEDSGQPTELSLTPGAPMELLCDAQ--GTPQPNITWHKDGQAL---TRLE 451

Query: 3746 TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
              N      L ++ +  RDAG YTC A +  G+   + ++   A  +IV
Sbjct: 452  N-NSRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIV 499



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 9/92 (9%)

Query: 1303 EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPA 1362
            ++  V+Q   FS   + +E V G+ + L+C ++  GD    + W  +G P++  H     
Sbjct: 1112 KEAPVLQGEAFS---YLVEPVGGS-IQLDCVVR--GDPVPDIHWIKDGLPLRGSHL---R 1162

Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEA 1394
            ++    +L +     +D+G Y C A N++G A
Sbjct: 1163 HQLQNGSLTIHRTERDDAGRYQCLAENEMGVA 1194



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 2/85 (2%)

Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
           EG+    + +      P   V W KDG P+         F     SL +  L A DAG+Y
Sbjct: 144 EGQEVRLDCEAD--GQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAY 201

Query: 844 TVRAVNKLGEAISTASIRVAARSTV 868
           T  A N  GE     ++ V    T+
Sbjct: 202 TCVAHNPAGEDARLHTVNVLVPPTI 226



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 3/70 (4%)

Query: 786 RNAHFEAQLTPV-SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
           R       + PV   P + V W KDG P+  S R T +   G+ +L I  ++  DAG +T
Sbjct: 239 RPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQR-TLLHGSGH-TLRISKVQLADAGIFT 296

Query: 845 VRAVNKLGEA 854
             A +  G A
Sbjct: 297 CVAASPAGVA 306



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 5/81 (6%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            L  GQ V LE  VE   +P  KI W ++G+ L   A  +  F      L + +L   DSG
Sbjct: 510  LAPGQLV-LECSVE--AEPAPKITWHRDGIVLQEDAHTQ--FPERGRFLQLQALSTADSG 564

Query: 2714 IYTCKATNLLGEAVSTASIKI 2734
             Y+C A N  G       ++I
Sbjct: 565  DYSCTARNAAGSTSVAFRVEI 585



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 82/336 (24%), Positives = 121/336 (36%), Gaps = 31/336 (9%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W KD  P++  S        G  +L I+ V   DAGHY C A N+ G      +L ++
Sbjct: 620  VSWRKDRVPLDPRSPRFEILPEG--SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL 677

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEE-EVKITQKPRFLGPLKGTNKIVEGQSA 1061
                  A S  P  L  + + +D  +   R ++   ++      L    G        SA
Sbjct: 678  ALLPCEA-SGSPKPL--VVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQ-----DSA 729

Query: 1062 HFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVAR 1121
             FE  V  +      +         T A+  QT  DF    +    +    +G+      
Sbjct: 730  QFECVVSNEVGEAHRLYQVTVHVPPTIADD-QT--DFTVTMMAPVVLTCHSTGIPAPTVS 786

Query: 1122 NAAGEAQLSA---SMTVETRSSIDTSS---IHRGLYEKTRHIEESKFVEPMYQIEEISKS 1175
             +   AQL A      V    +++      IH G Y  T     S  V   +    +  S
Sbjct: 787  WSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRY--TCSARNSAGVAHKHVFLTVQAS 844

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
             PV V+PL +       + + L C  E  G P   + W   G +V  G   +        
Sbjct: 845  -PV-VKPLPSVVRAVAEEEVLLPC--EASGIPRPTITWQKEGLNVATGVSTQV---LPGG 897

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSA--HTSAIVRV 1269
             L I HA+  D G Y   A N  GSA   T  +V+V
Sbjct: 898  QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQV 933



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP       DL  +E S A   C+          + W  +G+P+       TI   G ++
Sbjct: 934  PPVIENGLPDLSTTEGSHAFLPCKAR--GSPEPNITWDKDGQPVSGAEGKFTIQPSGELL 991

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEA 3641
            ++   +  +DAG YTC A N  G A
Sbjct: 992  VK--NLEGQDAGTYTCTAENAVGRA 1014



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 17/139 (12%)

Query: 1811 ESQHESALQKIQ-QLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE---------GQ 1860
            E    S LQ+     EDS  Y    +  V   QA  F+     P    E         G 
Sbjct: 1072 EQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGG 1131

Query: 1861 SAHYECRIEPYPDPNMRVEWYFNGKVLQSGH-RYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            S   +C +   P P+  + W  +G  L+  H R++  N     +L I     +D+G Y C
Sbjct: 1132 SIQLDCVVRGDPVPD--IHWIKDGLPLRGSHLRHQLQN----GSLTIHRTERDDAGRYQC 1185

Query: 1920 KAINNLGQAVSSIRLNVQS 1938
             A N +G A   + L +QS
Sbjct: 1186 LAENEMGVAKKVVILVLQS 1204



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 5/70 (7%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G     +C V    DP   I W  +G  +R  H     H     +L I  T  +D+G Y 
Sbjct: 1130 GGSIQLDCVVR--GDPVPDIHWIKDGLPLRGSH---LRHQLQNGSLTIHRTERDDAGRYQ 1184

Query: 2184 CKATNKLGEA 2193
            C A N++G A
Sbjct: 1185 CLAENEMGVA 1194



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 5/70 (7%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G +I  +C V    DP   I W  +  PL  G+  +  H     SL I  T  +D+G Y 
Sbjct: 1130 GGSIQLDCVVRG--DPVPDIHWIKDGLPL-RGSHLR--HQLQNGSLTIHRTERDDAGRYQ 1184

Query: 2848 CKATNSKGSA 2857
            C A N  G A
Sbjct: 1185 CLAENEMGVA 1194



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 3/57 (5%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            GD    + W+KDG P+  S       N    +LTI      DAG Y C A N +G A
Sbjct: 1141 GDPVPDIHWIKDGLPLRGSHLRHQLQNG---SLTIHRTERDDAGRYQCLAENEMGVA 1194



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 13/34 (38%), Positives = 22/34 (64%)

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L I   +  D G+Y+CK +N+ GEAV T ++ ++
Sbjct: 1    LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 34



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
            G P   V WL++ +P+E+S     +   G   L +  + P  +GTYTC A N   EA
Sbjct: 63   GVPAPTVTWLKDRMPVESSAVHGVVSRGG--RLQLSRLQPAQAGTYTCVAENTQAEA 117



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 16/129 (12%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEIS--VKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            L++    T DSG YSC A N  G   ++  V++  V   +   P     +         Q
Sbjct: 553  LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSV--------NQ 604

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPM-RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +A   C    V  P   + W  +  P+   S R + + + G + +     Q  D+G Y+C
Sbjct: 605  TALLPCQADGVPAP--LVSWRKDRVPLDPRSPRFEILPE-GSLRIQPVLAQ--DAGHYLC 659

Query: 3225 RAYNKYGED 3233
             A N  G D
Sbjct: 660  LASNSAGSD 668


>AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein.
          Length = 1237

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 80/255 (31%), Positives = 116/255 (45%), Gaps = 20/255 (7%)

Query: 4565 EDG---TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            EDG   +  L IL A   DSG Y C A N+ G A+  A   V  P       P      A
Sbjct: 21   EDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPD----EA 76

Query: 4622 PPEIIEPLK--DKI--VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD- 4676
            P  ++EPLK   K   V EG+  +F C ++GKP P ++W+   + + P +   M R  D 
Sbjct: 77   PAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDG 136

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
             + L++     +D G Y C A NSAG+   A +L V +P     L    PL+D+   E  
Sbjct: 137  GFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP----RLRFTRPLQDVEGREHG 192

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             A  + ++ +   PT  W RE   +     ++ I EG    L+I     +D G + C   
Sbjct: 193  IAVLECKVPNSRIPT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE-- 249

Query: 4797 TAAGQVETSAKLVVK 4811
               G+V T A + VK
Sbjct: 250  -MRGRVRTVANVTVK 263



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 62/241 (25%), Positives = 90/241 (37%), Gaps = 22/241 (9%)

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
           LR+   +  DSG Y   A N +G       L V  P ES   D       D       E 
Sbjct: 30  LRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP------DEAPAPVVEP 83

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
           ++ + K              V EGK  +F C V G+P PE+ W    R +  D    +  
Sbjct: 84  LKCAPKTFW-----------VNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYR 132

Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
           +  G   L +      D G+  C ARN +G+T    +L+V E       +F      +  
Sbjct: 133 DRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRL----RFTRPLQDVEG 188

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
           RE    VL  +   +  P   W ++   ++P  +     +G    L I R KA D   Y 
Sbjct: 189 REHGIAVLECKVPNSRIP-TAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYL 247

Query: 563 C 563
           C
Sbjct: 248 C 248



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 83/343 (24%), Positives = 127/343 (37%), Gaps = 42/343 (12%)

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRR-------QGRGGIVPPSFTLTAQNVNVTSGQ 4529
            DS V+   A N  G A+  A L V +          +    +V P      +   V  G+
Sbjct: 39   DSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEP-LKCAPKTFWVNEGK 97

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECVA 4588
              +    V G    ++ W   G+ + PD R  +  + DG + L +L    +D G Y C A
Sbjct: 98   HAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAA 157

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             NSAG+     +  V  P  +                  PL+D    E       CK+  
Sbjct: 158  RNSAGQTLSAVQLHVKEPRLR---------------FTRPLQDVEGREHGIAVLECKVPN 202

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
              +PT  W++ D+ + P + ++         L I     +D+G Y C      GRV   A
Sbjct: 203  SRIPTA-WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC---EMRGRVRTVA 258

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
             + V  P     LP     R + V EG+ A    + T +     +W R+G    E P   
Sbjct: 259  NVTVKGP-ILKRLP-----RKLDVLEGENAVLLVE-TLEAGVEGRWSRDG---EELPVIC 308

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                G+   L++     ED G      T + G   T+  L VK
Sbjct: 309  QSSSGHMHALVLPGVTREDAG----EVTFSLGNSRTTTLLRVK 347



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 64/260 (24%), Positives = 105/260 (40%), Gaps = 30/260 (11%)

Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            +V W K+G++V       + +ED    L++     +DSG+Y C           D E   
Sbjct: 764  EVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLC---------EIDDESA- 813

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE---FSCKIVGKPLPTVQWYKGD 4660
            S   T  +P         P  II P +D++      +E     C++  +  P V+WYK  
Sbjct: 814  SFTVTVTEP---------PVRIIYP-RDEVTLIAVTLECVVLMCELSREDAP-VRWYKDG 862

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
              ++ S+   + R      L +  A PED G++ C A + +   TV     VT+P     
Sbjct: 863  LEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVT----VTEP-PVQF 917

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
            L   T    + V  G+P     +++    P + W   G  + E    ++  EG   VL I
Sbjct: 918  LALETTPSPLCVAPGEPVVLSCELSRAGAPVV-WSHNGRPVQEGEGLELHAEGPRRVLCI 976

Query: 4781 GNTYEEDTGTFTCRATTAAG 4800
                    G +TC++  A G
Sbjct: 977  QAAGPAHAGLYTCQSGAAPG 996



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 44/144 (30%), Positives = 61/144 (42%), Gaps = 14/144 (9%)

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV--------IEKEQVVAPKFVERFS-- 498
           AL I    L DSGV  C ARN  G       L V         + ++  AP  VE     
Sbjct: 29  ALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAP-VVEPLKCA 87

Query: 499 --TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKA 555
             T  V EG+        +G P P I W  +G P++P+    ++ D  G   L +   +A
Sbjct: 88  PKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQA 147

Query: 556 SDAAWYQCTAQNVAGSTATRARLY 579
            D   Y C A+N AG T +  +L+
Sbjct: 148 KDRGLYVCAARNSAGQTLSAVQLH 171



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 15/147 (10%)

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQN--IEGLK- 3162
            + L IL  +  DSG Y C A N  G A+    L+ V +     P          +E LK 
Sbjct: 28   LALRILAARLPDSGVYVCHARNAHGHAQAGALLQ-VHQPPESPPADPDEAPAPVVEPLKC 86

Query: 3163 --------DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAY 3213
                    +G+ A F C V+   +P+  IEW+  G+P+    R     D  G  VL + Y
Sbjct: 87   APKTFWVNEGKHAKFRCYVMGKPEPE--IEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLY 144

Query: 3214 TQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             Q  D G YVC A N  G+  +   ++
Sbjct: 145  CQAKDRGLYVCAARNSAGQTLSAVQLH 171



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 78/359 (21%), Positives = 141/359 (39%), Gaps = 33/359 (9%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   ++W ++   +  SP   +    T   L++  V +EDS  +    ++       SA+
Sbjct: 761  PWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDE------SAS 814

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
              V       R  I+ P   +T   V +   + V L  +++  +   V W K+G +V+ +
Sbjct: 815  FTVTVTEPPVR--IIYPRDEVTLIAVTL---ECVVLMCELS-REDAPVRWYKDGLEVE-E 867

Query: 4558 IRNKILEEDGTYTLLILEA-YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
                +LE DG    L+L A  P+D G++ C     AG+   D+        T  +P  Q 
Sbjct: 868  SEALVLERDGPRCRLVLPAAQPEDGGEFVC----DAGD---DS---AFFTVTVTEPPVQF 917

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
             A    P    PL    VA G+ +  SC++     P V W    + ++  +  ++     
Sbjct: 918  LALETTPS---PL---CVAPGEPVVLSCELSRAGAPVV-WSHNGRPVQEGEGLELHAEGP 970

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
               L I  A P   G Y C +  + G  +++  ++V +P      P     R +    G 
Sbjct: 971  RRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTR-VRSTPGG 1029

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
              +    ++    P ++W ++G  +      Q+   G   VL +      D G + C A
Sbjct: 1030 DLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDA 1087



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 79/336 (23%), Positives = 127/336 (37%), Gaps = 33/336 (9%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E   E  P ++WY++   ++ S    +     +  L++     ED   F   A    G  
Sbjct: 848  ELSREDAP-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDA----GDD 902

Query: 4493 KCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGK 4552
                 + V E   Q       PS       + V  G+ V L  +++      V W  NG+
Sbjct: 903  SAFFTVTVTEPPVQFLALETTPS------PLCVAPGEPVVLSCELSRAGA-PVVWSHNGR 955

Query: 4553 KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
             VQ     ++  E     L I  A P  +G Y C +  + G          SL  T    
Sbjct: 956  PVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAP--------SLSFTVQVA 1007

Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672
            +P  +   AP      ++      G  +E    + G   P V+WYK  + +      Q+ 
Sbjct: 1008 EPPVRVV-APEAAQTRVRS---TPGGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLE 1062

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
            +      LR+  A   D G+Y C A   + R+ +   + V +P     +  LTPL    V
Sbjct: 1063 QAGARQVLRVQGARSGDAGEYLCDAPQDS-RIFL---VSVEEPLLVKLVSDLTPL---TV 1115

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
            +EG  A F+ ++ S     + WLR GA++   P  Q
Sbjct: 1116 HEGDDATFRCEV-SPPDADVTWLRNGAVVTPGPQRQ 1150



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 39/108 (36%), Positives = 54/108 (50%), Gaps = 14/108 (12%)

Query: 3819 APKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHR 3877
            AP  EP+   P       K+  V E +  +F C V  K +P+  IEW+  G+ LLP   R
Sbjct: 78   APVVEPLKCAP-------KTFWVNEGKHAKFRCYVMGKPEPE--IEWHWEGRPLLPDRRR 128

Query: 3878 --YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
              YR   D GFV L +LY  A+D G Y+C A N  G+  +   +  K+
Sbjct: 129  LMYRD-RDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKE 174



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 13/167 (7%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF--GMVVLEILGTKTTD 3117
            ++EG+ A +   ++  G     IEW + G+ +    R R +Y    G  VL++L  +  D
Sbjct: 93   VNEGKHAKFRCYVM--GKPEPEIEWHWEGRPLLPDRR-RLMYRDRDGGFVLKVLYCQAKD 149

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             G Y C A N  GQ   +V+L      K  + RFT  +Q++EG + G  A  EC    V 
Sbjct: 150  RGLYVCAARNSAGQTLSAVQLHV----KEPRLRFTRPLQDVEGREHG-IAVLEC---KVP 201

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +  +   W+   Q +    + + + +     L I   +  D G Y+C
Sbjct: 202  NSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC 248



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 29/85 (34%), Positives = 48/85 (56%), Gaps = 7/85 (8%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR---YRTSNDFGFAALDILTVYGE 1912
            ++EG+ A + C +   P+P   +EW++ G+ L    R   YR   D GF  L +L    +
Sbjct: 93   VNEGKHAKFRCYVMGKPEPE--IEWHWEGRPLLPDRRRLMYR-DRDGGFV-LKVLYCQAK 148

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQ 1937
            D G Y C A N+ GQ +S+++L+V+
Sbjct: 149  DRGLYVCAARNSAGQTLSAVQLHVK 173



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 51/170 (30%), Positives = 73/170 (42%), Gaps = 28/170 (16%)

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094
            +AL IL A   D+G Y+C A NA G A   + ++V              +  +    +  
Sbjct: 28   LALRILAARLPDSGVYVCHARNAHGHAQAGALLQV-------------HQPPESPPADPD 74

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            E P P+ E      P+     T   N  EG  A F C V  +  P   I+W   G+ +  
Sbjct: 75   EAPAPVVE------PLKCAPKTFWVN--EGKHAKFRCYV--MGKPEPEIEWHWEGRPLLP 124

Query: 2155 GHR---YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              R   YR   D G+V L +LY  A+D G Y+C A N  G+ ++   L V
Sbjct: 125  DRRRLMYRD-RDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV 172



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 33/104 (31%), Positives = 44/104 (42%), Gaps = 4/104 (3%)

Query: 2489 KLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYING 2548
            ++ QP E    +PD E   P+   +   P   W  +  H + R   +G P    EW+  G
Sbjct: 61   QVHQPPESPPADPD-EAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEG 119

Query: 2549 VELKMGSR--FRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
              L    R       D GFV L +    A D GLY+C A N AG
Sbjct: 120  RPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAG 162



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 25/156 (16%)

Query: 3218 DSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTP 3277
            DSG YVC A N +G          + + G  L+  QP         ES      + P+ P
Sbjct: 39   DSGVYVCHARNAHG----------HAQAGALLQVHQPP--------ESPPADPDEAPA-P 79

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD- 3336
              EP K   +   V    EG+ A F  R   +  P+ ++EW + G+ L    R   + D 
Sbjct: 80   VVEPLKCAPKTFWVN---EGKHAKF--RCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDR 134

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             G  +L +LYC  ++ G Y C A N  G+  +   L
Sbjct: 135  DGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQL 170



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 65/285 (22%), Positives = 117/285 (41%), Gaps = 45/285 (15%)

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLIL 4574
            S T T     V + +L R+D   T        W K+G+KV+ +    +++ DG    LIL
Sbjct: 561  SLTFTTSERVVLTCELSRVDFPAT--------WYKDGQKVE-ESELLVVKMDGRKHRLIL 611

Query: 4575 -EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
             EA  QDSG++EC    + G +            T   P         P  I++P +   
Sbjct: 612  PEAKVQDSGEFEC---RTEGVS-------AFFGVTVQDP---------PVHIVDPREHVF 652

Query: 4634 V--AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            V     + +  +C++  +  P V+WYK  + ++ S +  +        L +    P D G
Sbjct: 653  VHAITSECVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGG 711

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI-KP 4750
            +++CVA +     TV     +T        P+        VY       +  +T ++ +P
Sbjct: 712  EFQCVAGDECAYFTVT----ITDVSSWIVYPSGK------VYVAAVRLERVVLTCELCRP 761

Query: 4751 --TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
               ++W ++G  + E+P   +  E     L++     ED+G + C
Sbjct: 762  WAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLC 806



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 66  PGEPSPPIFEQIF---KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRY 122
           P E   P+ E +    K     +G +AKF   + G P P + W  +  PL+  ++  + Y
Sbjct: 73  PDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMY 131

Query: 123 NEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            ++ G   L +      D G Y C ARN  G+ + +V +
Sbjct: 132 RDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQL 170



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 47/195 (24%), Positives = 78/195 (40%), Gaps = 18/195 (9%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS---ILIIRQVFVEDS 4478
            V E + A+F     G+P P I+W+ E  P+   PD +   +  +    +L +     +D 
Sbjct: 93   VNEGKHAKFRCYVMGKPEPEIEWHWEGRPL--LPDRRRLMYRDRDGGFVLKVLYCQAKDR 150

Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
             ++   A N  G    +  L V+E R +         FT   Q+V      +  L+ KV 
Sbjct: 151  GLYVCAARNSAGQTLSAVQLHVKEPRLR---------FTRPLQDVEGREHGIAVLECKVP 201

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
             ++ I   W +  +++ P  + + +EE     L+I      D G Y C      G  R  
Sbjct: 202  NSR-IPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC---EMRGRVRTV 257

Query: 4599 AECVVSLPATKDKPK 4613
            A   V  P  K  P+
Sbjct: 258  ANVTVKGPILKRLPR 272



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 52/176 (29%), Positives = 73/176 (41%), Gaps = 34/176 (19%)

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEES 1160
            +AL I + R  DSGVY   ARNA G AQ  A +            +H+          ES
Sbjct: 28   LALRILAARLPDSGVYVCHARNAHGHAQAGALL-----------QVHQP--------PES 68

Query: 1161 KFVEPMYQIEEISKSKPVFVQPLSNPPP---VSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
               +P        ++    V+PL   P    V+EGK+    C +  MG P   +EW   G
Sbjct: 69   PPADP-------DEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYV--MGKPEPEIEWHWEG 119

Query: 1218 RSVTVGSRFKTY--YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            R +    R   Y   D GFV L +++  + D G Y   A N  G   ++  + V E
Sbjct: 120  RPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKE 174



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 9/87 (10%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY---DFGYVALDILYAYAE 2045
            V EG   H +     +  P   +EW+  GRP+    R +  Y   D G+V L +LY  A+
Sbjct: 93   VNEGK--HAKFRCYVMGKPEPEIEWHWEGRPLLPDRR-RLMYRDRDGGFV-LKVLYCQAK 148

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            D G Y+C A N+ G+  T S+V++  K
Sbjct: 149  DRGLYVCAARNSAGQ--TLSAVQLHVK 173



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 43/170 (25%), Positives = 63/170 (37%), Gaps = 25/170 (14%)

Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDT 1694
            +AL I++    DSG Y C A NA G A    +  VH           E   P +  L+  
Sbjct: 28   LALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCA 87

Query: 1695 SKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIE 1754
             K                F +         N+  H + R   +G P+  +EW   G P+ 
Sbjct: 88   PK---------------TFWV---------NEGKHAKFRCYVMGKPEPEIEWHWEGRPLL 123

Query: 1755 ASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
               R     D  G   L + Y   +D G Y C A N  G+ +++  L V+
Sbjct: 124  PDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVK 173



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 29/109 (26%), Positives = 55/109 (50%), Gaps = 5/109 (4%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GFVILEISPTYPEDS 3490
            + EG++A F   +    +P  ++EW+W G+ L    R   + D  G  +L++     +D 
Sbjct: 93   VNEGKHAKFRCYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDR 150

Query: 3491 GEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            G Y+C A N+ G+ ++   + V+  R  +  ++  + +EG    IA LE
Sbjct: 151  GLYVCAARNSAGQTLSAVQLHVKEPR--LRFTRPLQDVEGREHGIAVLE 197



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 77/358 (21%), Positives = 146/358 (40%), Gaps = 49/358 (13%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            WY++   ++ S    +     K  LI+ +  V+DS  F    E           + V++ 
Sbjct: 585  WYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEG----VSAFFGVTVQDP 640

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
                   IV P   +    V+  + + V L  +V   +   V W K+G++V+ +    +L
Sbjct: 641  PVH----IVDPREHVF---VHAITSECVMLACEVD-REDAPVRWYKDGQEVE-ESDFVVL 691

Query: 4564 EEDGTYTLLILEA-YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
            E +G +  L+L A  P D G+++CVA    G+  C    V     +     P  K   A 
Sbjct: 692  ENEGPHRRLVLPATQPSDGGEFQCVA----GD-ECAYFTVTITDVSSWIVYPSGKVYVAA 746

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIK-PSKYFQMSRTADEYTL 4680
              +            + +  +C++  +P   V+W K G+++++ P+   Q   T     L
Sbjct: 747  VRL------------ERVVLTCELC-RPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVL 793

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAA---KLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
               +   ED G+Y C   + +   TV      +++  P     L A+T L  +V+     
Sbjct: 794  PAVQL--EDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVT-LECVVL----- 845

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
                 +++ +  P ++W ++G  + E+    +  +G    L++     ED G F C A
Sbjct: 846  ---MCELSREDAP-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDA 899



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 10/147 (6%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL-PSGTRYK-STHDFSYVSLDITHTYEEDSG 2844
            EG +  F C V    +P  +IEW +  +PL P   R      D  +V L + +   +D G
Sbjct: 95   EGKHAKFRCYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRG 151

Query: 2845 IYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904
            +Y C A NS G   ++  L    +  + F T+  Q   G E      E ++   R   +P
Sbjct: 152  LYVCAARNSAGQTLSAVQLH-VKEPRLRF-TRPLQDVEGREHGIAVLECKVPNSR---IP 206

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHL 2931
               + + + ++P     Q+ EG V  L
Sbjct: 207  TAWFREDQRLLPCRKYEQIEEGTVRRL 233



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 11/124 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +G+ + +  R++   A    VL + G ++ D+G Y C A        +SV+   +
Sbjct: 1044 VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLL 1103

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
             K        T H        +G  A F C V P   PD  + W  NG  +    + ++ 
Sbjct: 1104 VKLVSDLTPLTVH--------EGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQRQSC 1152

Query: 3202 SDFG 3205
              +G
Sbjct: 1153 CSYG 1156



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 3/88 (3%)

Query: 3564 PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVILEIGGV 3622
            P    ++E   A F C ++        +EW   G+PLL   R     D  G  +L++   
Sbjct: 88   PKTFWVNEGKHAKFRCYVM--GKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYC 145

Query: 3623 YQRDAGLYTCKATNRHGEATVSCKLQVK 3650
              +D GLY C A N  G+   + +L VK
Sbjct: 146  QAKDRGLYVCAARNSAGQTLSAVQLHVK 173



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 5/81 (6%)

Query: 3707 VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGFIALDIDYIYARD 3764
            V EG    F C V  +G P   I+W   GRP     R  ++   D GF+ L + Y  A+D
Sbjct: 93   VNEGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKD 149

Query: 3765 AGEYTCRATNKWGSATTTAKI 3785
             G Y C A N  G   +  ++
Sbjct: 150  RGLYVCAARNSAGQTLSAVQL 170



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 2/103 (1%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D +  PV  P +   P+   + EG  A+F+  + G P P + W   G+ L+   +  +  
Sbjct: 74  DEAPAPVVEP-LKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYR 132

Query: 317 THN-HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             +    L+V   Q  D G Y   A N  G  +++  L V+ P
Sbjct: 133 DRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 175



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 38/180 (21%), Positives = 81/180 (45%), Gaps = 16/180 (8%)

Query: 4621 APPEIIEPLKDKI---VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
            +P  I+ P +DK+       + +  +C++     P   WYK  + ++ S+   +     +
Sbjct: 549  SPVHILSP-QDKVSLTFTTSERVVLTCELSRVDFPAT-WYKDGQKVEESELLVVKMDGRK 606

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE--G 4735
            + L + EA  +D G+++C    + G   V+A   VT  D   ++  + P   + V+    
Sbjct: 607  HRLILPEAKVQDSGEFEC---RTEG---VSAFFGVTVQDPPVHI--VDPREHVFVHAITS 658

Query: 4736 QPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
            +      ++  +  P ++W ++G  + E+    + +EG +  L++  T   D G F C A
Sbjct: 659  ECVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVA 717



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 9/159 (5%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C V     P V W+ + +++ +  +  +L NE  +  L++     SD G   CVA +   
Sbjct: 665 CEVDREDAP-VRWYKDGQEVEES-DFVVLENEGPHRRLVLPATQPSDGGEFQCVAGD--- 719

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
           E A+           +V P      + + +   E VVL       P   + W KDG  ++
Sbjct: 720 ECAYFTVTITDVSSWIVYPSGKVYVAAVRL---ERVVLTCELC-RPWAEVRWTKDGEEVV 775

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +P L +  +     L +P  +  D+  Y C   + + S
Sbjct: 776 ESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESAS 814



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIFNFGYVSLNIMHLRAED 839
           + EG++A F   +  +  P   +EW+ +GRP+    R  +    + G+V L +++ +A+D
Sbjct: 93  VNEGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKD 149

Query: 840 AGSYTVRAVNKLGEAISTASIRV 862
            G Y   A N  G+ +S   + V
Sbjct: 150 RGLYVCAARNSAGQTLSAVQLHV 172



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 37/164 (22%), Positives = 65/164 (39%), Gaps = 6/164 (3%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G+     C ++    P V W  N R +++    ++   E     L I     + +G+
Sbjct: 929  VAPGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEGLELHA-EGPRRVLCIQAAGPAHAGL 986

Query: 463  VTCVARNKSGETAFQCRLNVIEKE-QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
             TC +    G  +    + V E   +VVAP+  +  + +    G  + L     G   P 
Sbjct: 987  YTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQ--TRVRSTPGGDLELVVHLSGPGGP- 1043

Query: 522  ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
            + W KDG  +     +++   G    L +  A++ DA  Y C A
Sbjct: 1044 VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDA 1087



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 65/229 (28%), Positives = 90/229 (39%), Gaps = 32/229 (13%)

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226
            +AL IL     DSG Y+C A N  G A     L+V  H+        P+           
Sbjct: 28   LALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--HQPPESPPADPD----------- 74

Query: 2227 GHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ 2286
                  E   P + P +   +   T  V EGK A F C V  +  P   IE++  G+ L 
Sbjct: 75   ------EAPAPVVEPLKCAPK---TFWVNEGKHAKFRCYV--MGKPEPEIEWHWEGRPLL 123

Query: 2287 SAAR--FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV-TAKGSIISE 2343
               R   +   D G+V L + +C  +D G Y   A N+ G   SA+ + V   +      
Sbjct: 124  PDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP 182

Query: 2344 SQRPEGLEK-IRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEG 2391
             Q  EG E  I  LE   P  R  IP    R+      P +  + I+EG
Sbjct: 183  LQDVEGREHGIAVLECKVPNSR--IPTAWFREDQRLL-PCRKYEQIEEG 228



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/112 (26%), Positives = 54/112 (48%), Gaps = 9/112 (8%)

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
            L ++ +   + P    E P PV    P+   P      + EG+ A F C ++  G P  +
Sbjct: 59   LLQVHQPPESPPADPDEAPAPVVE--PLKCAP--KTFWVNEGKHAKFRCYVM--GKPEPE 112

Query: 2410 VEW-FRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +EW +    L+ D  R+  +  D G+V + + + + +D G+Y+C A N  G+
Sbjct: 113  IEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQ 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            TTPS L ++        C L   + +   V W HNG+P+  G  ++   +    +L I  
Sbjct: 922  TTPSPLCVAPGEPVVLSCEL---SRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQA 978

Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                 AGLYTC++    G  ++S  +QV
Sbjct: 979  AGPAHAGLYTCQSGAAPGAPSLSFTVQV 1006



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 6/93 (6%)

Query: 1048 PLKGTNK---IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF-GYVAL 1103
            PLK   K   + EG+ A F   V  + +    +EW++ G+ +    R   Y D  G   L
Sbjct: 83   PLKCAPKTFWVNEGKHAKFRCYVMGKPE--PEIEWHWEGRPLLPDRRRLMYRDRDGGFVL 140

Query: 1104 DIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             +   +A+D G+Y   ARN+AG+   +  + V+
Sbjct: 141  KVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVK 173



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            G D +  V LSG   P V W+K+G+RL +  + ++        LRV+  +  D+G Y
Sbjct: 1028 GGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEY 1083



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 1/74 (1%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L V  GEPVVL+        P + W  +G P+     L +H +G    L I  A  + 
Sbjct: 925 SPLCVAPGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAH 983

Query: 558 AAWYQCTAQNVAGS 571
           A  Y C +    G+
Sbjct: 984 AGLYTCQSGAAPGA 997



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 37/125 (29%), Positives = 50/125 (40%), Gaps = 8/125 (6%)

Query: 623 PYIPPGEEDRVYPPPQFIVPLKSVTA---MEGGKIHFETRIEPVGDPTMKIEWLKNGQSI 679
           P  PP + D    P   + PLK       +  GK H + R   +G P  +IEW   G+ +
Sbjct: 66  PESPPADPDEA--PAPVVEPLKCAPKTFWVNEGK-HAKFRCYVMGKPEPEIEWHWEGRPL 122

Query: 680 EASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERT 737
               R      R G   L +L    +D G Y C A ++ G   +   LHV  PR    R 
Sbjct: 123 LPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP 182

Query: 738 SQHPE 742
            Q  E
Sbjct: 183 LQDVE 187



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 38/148 (25%), Positives = 57/148 (38%), Gaps = 8/148 (5%)

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477
           RP+ EV W  +  ++ +     +L  E     L++  V L DSG   C   ++S      
Sbjct: 760 RPWAEVRWTKDGEEVVES-PALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESAS---- 814

Query: 478 CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
               V   E  V   +     TL     E VVL         P + W KDG+ +  +  L
Sbjct: 815 --FTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAP-VRWYKDGLEVEESEAL 871

Query: 538 RIHTDGGASTLDIPRAKASDAAWYQCTA 565
            +  DG    L +P A+  D   + C A
Sbjct: 872 VLERDGPRCRLVLPAAQPEDGGEFVCDA 899



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 5/82 (6%)

Query: 1585 KNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSR--FTETNNFGFVALDIMSC 1642
            K   + EG+ A F  R   +     ++EW+   +PL    R       + GFV L ++ C
Sbjct: 89   KTFWVNEGKHAKF--RCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYC 145

Query: 1643 LPEDSGTYTCRAINALGEAVTS 1664
              +D G Y C A N+ G+ +++
Sbjct: 146  QAKDRGLYVCAARNSAGQTLSA 167



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 17/156 (10%)

Query: 424 TWFINDRQIRDDYNH--------KILVNESG-NHALMITNVTLSDSGVVTCVARNKSGET 474
           TWF+N  +++ +           +  + + G  H L++  V   DSG +   +     ++
Sbjct: 482 TWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDS 541

Query: 475 AFQCRLNVIEKE-QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
           A    L + E    +++P+  ++ S L     E VVL         P  TW KDG  +  
Sbjct: 542 A---ALTIQESPVHILSPQ--DKVS-LTFTTSERVVLTCELSRVDFPA-TWYKDGQKVEE 594

Query: 534 NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           +  L +  DG    L +P AK  D+  ++C  + V+
Sbjct: 595 SELLVVKMDGRKHRLILPEAKVQDSGEFECRTEGVS 630



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 5/85 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKL--TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P+ +IEW++ G+ L    R  +    D GFV L ++    +D G+Y C A N  G+  T 
Sbjct: 109  PEPEIEWHWEGRPLLPDRRRLMYRDRDGGFV-LKVLYCQAKDRGLYVCAARNSAGQ--TL 165

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLE 3023
            S V    K+  +  T+  +  EG E
Sbjct: 166  SAVQLHVKEPRLRFTRPLQDVEGRE 190



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 3/70 (4%)

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD-FGYVAMNFGWVYPEDSGE 4045
            E +  KF C +  +G P  ++EW + G+PLL   R     D  G   +   +   +D G 
Sbjct: 95   EGKHAKFRCYV--MGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGL 152

Query: 4046 YLCRATNLYG 4055
            Y+C A N  G
Sbjct: 153  YVCAARNSAG 162



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V   R  FT+PLQ+++  + G  A  +C+   V +  +   WFR ++ +    +  +  +
Sbjct: 172  VKEPRLRFTRPLQDVEGREHG-IAVLECK---VPNSRIPTAWFREDQRLLPCRKYEQIEE 227

Query: 2431 FGYVSMTISHVRDEDEGVYMC 2451
                 + I  ++ +D+G+Y+C
Sbjct: 228  GTVRRLIIHRLKADDDGIYLC 248



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 1185 NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244
            +P  V+ G+ + L C L   G P   V W HNGR V  G   + + +     L I  A  
Sbjct: 925  SPLCVAPGEPVVLSCELSRAGAP---VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGP 981

Query: 1245 ADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            A  G YT ++    G+   S  V+V E
Sbjct: 982  AHAGLYTCQSGAAPGAPSLSFTVQVAE 1008



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 5/107 (4%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYVALDIIDLIAEDS 1514
            V EG+H  F C +    +   ++EW   G+P+    R     D  G   L ++   A+D 
Sbjct: 93   VNEGKHAKFRCYVMGKPEP--EIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDR 150

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLEQ-IQVLE 1559
            G+Y C A N  G    + +L  +       R  Q+  G E  I VLE
Sbjct: 151  GLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLE 197



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/146 (20%), Positives = 58/146 (39%), Gaps = 12/146 (8%)

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P   V W+ +  ++      ++ + ++G    L +      D+G   C A   S      
Sbjct: 1040 PGGPVRWYKDGERLASQ--GRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDS------ 1091

Query: 478  CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
             R+ ++  E+ +  K V   + L V EG+        V  P   +TW ++G  + P P+ 
Sbjct: 1092 -RIFLVSVEEPLLVKLVSDLTPLTVHEGDDATFRCE-VSPPDADVTWLRNGAVVTPGPQR 1149

Query: 538  R-IHTDGGASTLDIPRAKASDAAWYQ 562
            +   + GG       +A+   + W Q
Sbjct: 1150 QSCCSYGGCRMCGQRKARTCVSKWRQ 1175



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 1/75 (1%)

Query: 1329 HLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY-VALDLLSVYPEDSGVYTCQA 1387
            H + R   +G     +EW   G+P+    R     + D    L +L    +D G+Y C A
Sbjct: 98   HAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAA 157

Query: 1388 TNQLGEAVTSCALRV 1402
             N  G+ +++  L V
Sbjct: 158  RNSAGQTLSAVQLHV 172



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 3/81 (3%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V  G PV L   L+    P   V W  NGRPVQ+G   +   +     L I  A     G
Sbjct: 929  VAPGEPVVLSCELSRAGAP---VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAG 985

Query: 2049 TYMCKATNAVGEAVTTSSVKV 2069
             Y C++  A G    + +V+V
Sbjct: 986  LYTCQSGAAPGAPSLSFTVQV 1006


>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
            protein.
          Length = 2213

 Score = 97.9 bits (233), Expect = 8e-19
 Identities = 96/389 (24%), Positives = 155/389 (39%), Gaps = 45/389 (11%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P P + W+RE   I   P  +I       ++I+     +  A +      + G  K S  
Sbjct: 219  PRPQVTWFREGHKI--IPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPF 276

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID---VYWLKNGKKV 4554
            + +   R  G    + P+  +   N +V +G        +   +P++   V W +NG ++
Sbjct: 277  IHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRI 336

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                    L   G + L I      D+G Y C A               +LP +  +P  
Sbjct: 337  TSG-----LHSFGRH-LTISNPTSADTGPYVCEA---------------ALPGSAFEPAR 375

Query: 4615 QTKAANA--PPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671
             T       PP      + +I AE  + ++  C+ +G PLPT+QWYK D +         
Sbjct: 376  ATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYK-DAISISRLQNPR 434

Query: 4672 SRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT--PLRD 4729
             +      LRI +  PED G ++C A N  G +     L VT     +  P  T  P+ D
Sbjct: 435  YKVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVT-----NIAPVFTQRPV-D 488

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIP----ETPDFQMIHEGNNAVLLIGNTYE 4785
              V +G  A  + +++   KP I W RE  ++       P F ++  G    L I   + 
Sbjct: 489  TTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGG---LQIAPVFI 545

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            +D G +TC A    G +  SA L V ++T
Sbjct: 546  QDAGNYTCYAANTEGSLNASATLTVWNRT 574



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 82/297 (27%), Positives = 127/297 (42%), Gaps = 45/297 (15%)

Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENP-NGCI 347
           ++  PRP+VTWF+ G ++I SN+  I T  N   +    T  SD+G Y + A N  NG  
Sbjct: 215 ITSYPRPQVTWFREGHKIIPSNRIAI-TLENQLVILATTT--SDAGAYYVQAVNEKNG-- 269

Query: 348 VTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407
                   E+ T  ++      +++  +   T E        +AP  V    +R V  G 
Sbjct: 270 --------ENKTSPFI------HLSIARDVGTPE-------TMAPTIVVPPGNRSVVAGS 308

Query: 408 M-TRFDCRVTGRPYPE--VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
             T  +C  + RP  +  VTW  N  +I         ++  G H L I+N T +D+G   
Sbjct: 309 SETTLECIASARPVEDLSVTWKRNGVRITSG------LHSFGRH-LTISNPTSADTGPYV 361

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARAVGTPTPRIT 523
           C A      +AF+          +  P F  E  S ++    E V +  +A+G P P + 
Sbjct: 362 CEAALPG--SAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQ 419

Query: 524 WQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           W KD + I  + NP  ++   GG   L I + +  D+  +QC A N  G   T   L
Sbjct: 420 WYKDAISISRLQNPRYKVLASGG---LRIQKLRPEDSGIFQCFASNEGGEIQTHTYL 473



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 69/306 (22%), Positives = 125/306 (40%), Gaps = 30/306 (9%)

Query: 4511 IVPPSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDG 4567
            I PP FT   ++ ++    + V +  +  G     + W K+   +    + R K+L   G
Sbjct: 383  IEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGG 442

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
               L I +  P+DSG ++C A N  GE +      V+               N  P   +
Sbjct: 443  ---LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVT---------------NIAPVFTQ 484

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI-KPSKYFQMSRTADEYTLRISEAF 4686
               D  V +G      C++ G P P + W + + ++   S         +   L+I+  F
Sbjct: 485  RPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVF 544

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
             +D G+Y C A N+ G +  +A L V      +    + P  D VV +G  A      T 
Sbjct: 545  IQDAGNYTCYAANTEGSLNASATLTVW-----NRTSIVHPPEDHVVIKGTTATLHCGATH 599

Query: 4747 KIKPTIQ--WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
              + +++  W ++   +  +   +++ E + + LLI  T+  D G ++C   +  G    
Sbjct: 600  DPRVSLRYVWKKDNVALTPSSTSRIVVEKDGS-LLISQTWSGDIGDYSCEIVSEGGNDSR 658

Query: 4805 SAKLVV 4810
             A+L V
Sbjct: 659  MARLEV 664



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 80/320 (25%), Positives = 129/320 (40%), Gaps = 36/320 (11%)

Query: 4409 KPPIFTKKMQPCRVFEHEQA-RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP FT + +     E E+      +  G PLP ++WY++   I    + +    ++   
Sbjct: 384  EPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGG- 442

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I+++  EDS +F   A N GG  +    L V           + P FT    +  VT 
Sbjct: 443  LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTN---------IAPVFTQRPVDTTVTD 493

Query: 4528 GQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIR--NKILEEDGTYTLLILEAYPQDSGKY 4584
            G    L  +V+G  KP   +  +N       +R    +L E G   L I   + QD+G Y
Sbjct: 494  GMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESG--GLQIAPVFIQDAGNY 551

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C A N+ G     A   V    +                I+ P +D +V +G      C
Sbjct: 552  TCYAANTEGSLNASATLTVWNRTS----------------IVHPPEDHVVIKGTTATLHC 595

Query: 4645 KIVGKPLPTVQ--WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                 P  +++  W K +  + PS   ++    D  +L IS+ +  D GDY C   +  G
Sbjct: 596  GATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDG-SLLISQTWSGDIGDYSCEIVSEGG 654

Query: 4703 RVTVAAKLKVTQ-PDQADNL 4721
              +  A+L+V + P    NL
Sbjct: 655  NDSRMARLEVIELPHSPQNL 674



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 63/244 (25%), Positives = 99/244 (40%), Gaps = 18/244 (7%)

Query: 341 ENPNGCIVTSGYLAVES--PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
           +NP   ++ SG L ++   P +S +     Q     +  E +    +    +AP F +  
Sbjct: 431 QNPRYKVLASGGLRIQKLRPEDSGI----FQCFASNEGGEIQTHTYLDVTNIAPVFTQRP 486

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH--KILVNESGNHALMITNVT 456
            D  VT+G      C V+G P P +TW   +  +        + ++ ESG   L I  V 
Sbjct: 487 VDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESG--GLQIAPVF 544

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
           + D+G  TC A N  G       L V  +  +V P          V +G    L+  A  
Sbjct: 545 IQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPP-----EDHVVIKGTTATLHCGATH 599

Query: 517 TP--TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            P  + R  W+KD V + P+   RI  +   S L I +  + D   Y C   +  G+ + 
Sbjct: 600 DPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLL-ISQTWSGDIGDYSCEIVSEGGNDSR 658

Query: 575 RARL 578
            ARL
Sbjct: 659 MARL 662



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 50/170 (29%), Positives = 69/170 (40%), Gaps = 13/170 (7%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C+  G P P + W+ +   I    N +  V  SG   L I  +   DSG+  C A N+ G
Sbjct: 408 CQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGG--LRIQKLRPEDSGIFQCFASNEGG 465

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI- 531
           E      L+V      +AP F +R     V +G   +L     G P P ITW+++   + 
Sbjct: 466 EIQTHTYLDVTN----IAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILA 521

Query: 532 ---IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +  P   +   GG   L I      DA  Y C A N  GS    A L
Sbjct: 522 SGSVRIPRFMLLESGG---LQIAPVFIQDAGNYTCYAANTEGSLNASATL 568



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 40/147 (27%), Positives = 66/147 (44%), Gaps = 11/147 (7%)

Query: 422 EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
           E +W +  + +RDD     L   S  +  +I ++   D+G   CV RN+ G  A   R +
Sbjct: 129 EGSWPLEFKWMRDDSE---LTTYSSEYKYIIPSLQKLDAGFYRCVVRNRMG--ALLQRKS 183

Query: 482 VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT-PTPRITWQKDGVPIIPNPELRIH 540
             E +      F++      V +G   +LN   + + P P++TW ++G  IIP+  + I 
Sbjct: 184 --EVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAIT 241

Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQN 567
            +   + L I     SDA  Y   A N
Sbjct: 242 LE---NQLVILATTTSDAGAYYVQAVN 265



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH-RYRTSNDF 1899
            N AP F TQ    T +++G +A   C +   P P   + W     +L SG  R       
Sbjct: 477  NIAPVF-TQRPVDTTVTDGMTAILRCEVSGAPKP--AITWKRENHILASGSVRIPRFMLL 533

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
                L I  V+ +D+G YTC A N  G   +S  L V ++ SI+
Sbjct: 534  ESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIV 577



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 13/136 (9%)

Query: 3530 GTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSM 3589
            G     A+ EG  G + T T    +   P FT  P D  +++  +A   C +      + 
Sbjct: 454  GIFQCFASNEG--GEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPA- 510

Query: 3590 RVEWFHNGKPLLTGSRVKTINDFGFVILEIGG-----VYQRDAGLYTCKATNRHGEATVS 3644
             + W      L +GS    +    F++LE GG     V+ +DAG YTC A N  G    S
Sbjct: 511  -ITWKRENHILASGS----VRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNAS 565

Query: 3645 CKLQVKGRQGIILEPQ 3660
              L V  R  I+  P+
Sbjct: 566  ATLTVWNRTSIVHPPE 581



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 35/112 (31%), Positives = 48/112 (42%), Gaps = 4/112 (3%)

Query: 1698 QRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR-NGVPIEAS 1756
            Q H+  D V   APVFT    D  V +   A     +   G PK  + W R N +    S
Sbjct: 468  QTHTYLD-VTNIAPVFTQRPVDTTVTDGMTAILRCEVS--GAPKPAITWKRENHILASGS 524

Query: 1757 NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
             R+          L +  V  +D+G YTC A N  G    S+TL V ++ S+
Sbjct: 525  VRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSI 576



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 932  RLEPIGDSTLRVEWLKDGRPVEASS-RITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAI 990
            R E  G     + W ++   + + S RI  F       L I  V + DAG+YTC A N  
Sbjct: 500  RCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTE 559

Query: 991  GQATTSANLTIVTKKDII 1008
            G    SA LT+  +  I+
Sbjct: 560  GSLNASATLTVWNRTSIV 577



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI--ITTHNHTTL 323
           P   Q+P ++ + +G  A  + ++SG P+P +TW K    ++ S    I          L
Sbjct: 480 PVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITW-KRENHILASGSVRIPRFMLLESGGL 538

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           ++      D+G+YT  A N  G +  S  L V + T
Sbjct: 539 QIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRT 574



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 3718 RVEPVGDPTMRIDWFHNGRPFATGS-RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKW 3776
            R E  G P   I W       A+GS R+          L I  ++ +DAG YTC A N  
Sbjct: 500  RCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTE 559

Query: 3777 GSATTTAKITCSAKRDIV 3794
            GS   +A +T   +  IV
Sbjct: 560  GSLNASATLTVWNRTSIV 577



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 33/118 (27%), Positives = 48/118 (40%), Gaps = 6/118 (5%)

Query: 1171 EISKSKPVFVQ-PLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS-RFKT 1228
            +++   PVF Q P+     V++G    L C  E  G P   + W      +  GS R   
Sbjct: 474  DVTNIAPVFTQRPVDTT--VTDGMTAILRC--EVSGAPKPAITWKRENHILASGSVRIPR 529

Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286
            +       L I      D G YT  A N  GS + SA + V  R+ IV   ++   I+
Sbjct: 530  FMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIK 587



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/45 (37%), Positives = 23/45 (51%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            PVF   P   TV +G  A   C V+G PKP + W    + + +GS
Sbjct: 480  PVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGS 524



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 9/85 (10%)

Query: 794 LTPVSD-PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVN-KL 851
           L P++  P  +V W+++G  I  S+RI        V   I+     DAG+Y V+AVN K 
Sbjct: 212 LLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLV---ILATTTSDAGAYYVQAVNEKN 268

Query: 852 GEAISTASIRVAARSTVTADLGIPE 876
           GE  ++  I +    ++  D+G PE
Sbjct: 269 GENKTSPFIHL----SIARDVGTPE 289



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 10/116 (8%)

Query: 263 VSPPKIAQKPRN---SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL--INSNKHEIITT 317
           + PP    +P +   ++++E  D   Q    G P P + W+K+   +  + + +++++ +
Sbjct: 383 IEPPYFTAEPESRISAEVEETVDIGCQAM--GVPLPTLQWYKDAISISRLQNPRYKVLAS 440

Query: 318 HNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
                LR++  +  DSG +   A N  G I T  YL V +    + Q      +TD
Sbjct: 441 GG---LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTD 493



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 41/168 (24%), Positives = 67/168 (39%), Gaps = 11/168 (6%)

Query: 3082 IEWFYNGKTIEASHRIR-TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            ++W+ +  +I      R  V A G + ++ L  +  DSG + C A+N+ G+ +    L+ 
Sbjct: 418  LQWYKDAISISRLQNPRYKVLASGGLRIQKL--RPEDSGIFQCFASNEGGEIQTHTYLDV 475

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH-STRIK 3199
             + +    P FT    +   + DG +A   C V     P   I W      +   S RI 
Sbjct: 476  TNIA----PVFTQRPVDTT-VTDGMTAILRCEVSGAPKP--AITWKRENHILASGSVRIP 528

Query: 3200 TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGV 3247
                     L IA     D+G Y C A N  G     AT+  + +  +
Sbjct: 529  RFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSI 576



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 38/155 (24%), Positives = 59/155 (38%), Gaps = 3/155 (1%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH-RYRTVYD 3883
            + +  P F  +    TV  ++G+    R E    PK  I W R   +L SG  R      
Sbjct: 475  VTNIAPVFTQRPVDTTV--TDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFML 532

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEAL 3943
            +    L I  V+ +D+G Y C A N  G     AT++      I+   +    +K + A 
Sbjct: 533  LESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTAT 592

Query: 3944 TQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQ 3978
                AT     S  Y+ + D   +      R V +
Sbjct: 593  LHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVE 627



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 51/194 (26%), Positives = 86/194 (44%), Gaps = 21/194 (10%)

Query: 394 FVKVCQDRDVTEGKMTRFDCR-VTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           F+   Q + V++G+    +   +T  P P+VTWF    +I    +++I +  +  + L+I
Sbjct: 193 FMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIP--SNRIAI--TLENQLVI 248

Query: 453 TNVTLSDSGVVTCVARN-KSGE--TAFQCRLNV---IEKEQVVAPKFVERFSTLNVREG- 505
              T SD+G     A N K+GE  T+    L++   +   + +AP  V      +V  G 
Sbjct: 249 LATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGS 308

Query: 506 EPVVLNARAVGTPTP--RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
               L   A   P     +TW+++GV I       +H+ G   T+  P   ++D   Y C
Sbjct: 309 SETTLECIASARPVEDLSVTWKRNGVRITSG----LHSFGRHLTISNP--TSADTGPYVC 362

Query: 564 TAQNVAGSTATRAR 577
            A  + GS    AR
Sbjct: 363 EAA-LPGSAFEPAR 375



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 47/175 (26%), Positives = 70/175 (40%), Gaps = 20/175 (11%)

Query: 3060 ISEGQIAHYEASLIP-TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            +S+G+ A    +L+P T      + WF  G  I  S+RI       +V   IL T T+D+
Sbjct: 202  VSQGRAAIL--NLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLV---ILATTTSDA 256

Query: 3119 GTYSCRATN-KWGQAEISVKLEC-----VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172
            G Y  +A N K G+ + S  +       V   +   P       N   +        EC 
Sbjct: 257  GAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECI 316

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKT-VSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                   D+ + W  NG       RI + +  FG   L I+   + D+G YVC A
Sbjct: 317  ASARPVEDLSVTWKRNG------VRITSGLHSFG-RHLTISNPTSADTGPYVCEA 364



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 6/103 (5%)

Query: 3419 APVFTV-PLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFRTFCDFG 3476
            APVFT  P+     + +G  A     ++    P   + W      L +GS R   F    
Sbjct: 479  APVFTQRPVDT--TVTDGMTAILRCEVSGAPKP--AITWKRENHILASGSVRIPRFMLLE 534

Query: 3477 FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNII 3519
               L+I+P + +D+G Y C A N  G    +A++ V  + +I+
Sbjct: 535  SGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIV 577



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 1/77 (1%)

Query: 659 RIEPVGDPTMKIEWLKNGQSIEASS-RFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSAT 717
           R E  G P   I W +    + + S R           L +  + IQD+G YTC A +  
Sbjct: 500 RCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTE 559

Query: 718 GVAETKAVLHVTPRATI 734
           G     A L V  R +I
Sbjct: 560 GSLNASATLTVWNRTSI 576



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
            L IA V  +D+G YT  A N  G    SA++TV  R+SI
Sbjct: 538  LQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSI 576


>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
            protein.
          Length = 4391

 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 104/424 (24%), Positives = 174/424 (41%), Gaps = 48/424 (11%)

Query: 4394 AQTQERVV--EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI 4451
            AQ Q  V+   G + P  P +  ++ +   V     A       G P P I W +   P+
Sbjct: 3194 AQKQVEVIVDTGAMAPGAPQVQAEEAE-LTVEAGHTATLRCSATGSPAPTIHWSKLRSPL 3252

Query: 4452 KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGI 4511
                  +  T      LII +V  +DS  +   A +  G A+ +  L VE          
Sbjct: 3253 PWQHRLEGDT------LIIPRVAQQDSGQYICNATSPAGHAEATIILHVES--------- 3297

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
             PP  T   ++ +V +G+ V+L     GT P+   W + G  +  +   RN++L  +   
Sbjct: 3298 -PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFE--- 3353

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP- 4628
                  A P+DSG+Y C   N  G A   A+ +V  P     P     A + P   + P 
Sbjct: 3354 -----RAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP-PGSLPATSIPAGSTPTVQVTPQ 3407

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L+ K +  G ++EF C +       ++W+K    + P        +  +  LRI      
Sbjct: 3408 LETKSI--GASVEFHCAVPSDQGTQLRWFKEGGQLPP------GHSVQDGVLRIQNLDQS 3459

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             +G Y C A+   G+   +A+L V Q   +  +   T ++ +VV  G   +F+       
Sbjct: 3460 CQGTYICQAHGPWGKAQASAQL-VIQALPSVLINIRTSVQTVVV--GHAVEFECLALGDP 3516

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            KP + W + G  +   P   ++  G   V+ I +    D G + C AT AAG  ++   L
Sbjct: 3517 KPQVTWSKVGGHL--RPG--IVQSG--GVVRIAHVELADAGQYRCTATNAAGTTQSHVLL 3570

Query: 4809 VVKS 4812
            +V++
Sbjct: 3571 LVQA 3574



 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 107/422 (25%), Positives = 164/422 (38%), Gaps = 57/422 (13%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQI 4459
            +  PV    PP  T  +QP ++     A F     G P P ++W     P    P   QI
Sbjct: 1863 LSAPVVSIHPPQLT--VQPGQL-----AEFRCSATGSPTPTLEW--TGGPGGQLPAKAQI 1913

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            H      IL +  V   D A +   A +  G     A L V      G GG   P   ++
Sbjct: 1914 HG----GILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVH-----GGGG---PRVQVS 1961

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             +   V +G+ VRL  +  G     + W K G  + P  R+   E     TLLI      
Sbjct: 1962 PERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARS---ERTDIATLLIPAITTA 2018

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y CVA + AG A+   + VV L A+   P P  K  ++ P          V EGQ 
Sbjct: 2019 DAGFYLCVATSPAGTAQARMQVVV-LSASDASP-PGVKIESSSPS---------VTEGQT 2067

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            ++ +C + G     V WY+    + P      SR      LR+ +  P D G+Y C   N
Sbjct: 2068 LDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSR------LRLPQVSPADSGEYVCRVEN 2121

Query: 4700 SAG----RVTVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKP 4750
             +G     +TV+             +P  T P+R       V EGQ       +  +   
Sbjct: 2122 GSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHA 2181

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             + W + G  +P        H+ + ++L +      D+G + C     +G +E S  + +
Sbjct: 2182 QVTWHKRGGSLPAR------HQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235

Query: 4811 KS 4812
            ++
Sbjct: 2236 EA 2237



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 100/412 (24%), Positives = 148/412 (35%), Gaps = 43/412 (10%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIH 4460
            EG     + P+ +       V + + A F+        P+ ++W   N  ++++    +H
Sbjct: 3013 EGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VH 3068

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                 SI+ I      +   +  VA N  G A+   NL V            PP+ ++  
Sbjct: 3069 ISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG----------PPTVSVLP 3118

Query: 4521 QN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            +  V V  G+ V L+    G       W +         +      D    L I  A P 
Sbjct: 3119 EGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPS 3178

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y C+A N+ G A+   E +V   A      PQ +A  A         +  V  G  
Sbjct: 3179 DAGTYVCLAQNALGTAQKQVEVIVDTGAMA-PGAPQVQAEEA---------ELTVEAGHT 3228

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
                C   G P PT+ W    KL  P  + Q     D  TL I     +D G Y C A +
Sbjct: 3229 ATLRCSATGSPAPTIHW---SKLRSPLPW-QHRLEGD--TLIIPRVAQQDSGQYICNATS 3282

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
             AG       L V  P  A  +P         V  G+  Q +         T QW R G+
Sbjct: 3283 PAGHAEATIILHVESPPYATTVP-----EHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 3337

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P            N +L       ED+G + CR T   G  E  A+L+V+
Sbjct: 3338 SLPGRA------TARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQ 3383



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 77/353 (21%), Positives = 148/353 (41%), Gaps = 32/353 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L + QV   DS  +        GT + S  + ++++        V     + + + ++
Sbjct: 2486 SRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASL 2545

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             +G  + L+  V    P  + W K G  +    R++I+       L I +  P DSG+Y 
Sbjct: 2546 ANGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGS----RLRIPQVTPADSGEYV 2599

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C   N AG    +   +V++  +     P      +PP  IE     +V EGQ ++ +C 
Sbjct: 2600 CHVSNGAGSR--ETSLIVTIQGSGSSHVPSV----SPPIRIESSSPTVV-EGQTLDLNCV 2652

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            +  +P   + WYK G  L  PS++    +T   + LR+ +    D G+Y C A N+   +
Sbjct: 2653 VARQPQAIITWYKRGGSL--PSRH----QTHGSH-LRLHQMSVADSGEYVCRANNNIDAL 2705

Query: 4705 TVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + V+    + + P  + P+R       V EG+       +  +    + W + G 
Sbjct: 2706 EASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG 2765

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +P        H+   + L + +    D+G + CR   ++G +E S  + +++
Sbjct: 2766 SLPSH------HQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEA 2812



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 90/356 (25%), Positives = 148/356 (41%), Gaps = 41/356 (11%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S+L + QV   DS  +        G  + S  + +E     G    +PP   + + +  V
Sbjct: 2201 SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGP---IPP-VRIESSSSTV 2256

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L   V G     V W K G  +    R+++        L I +A P D+G+Y 
Sbjct: 2257 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA--RHQVRGS----RLYIFQASPADAGQYV 2310

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N       +A   V++  T+        A +  P  IEP   + VAEGQ ++ +C 
Sbjct: 2311 CRASNGM-----EASITVTVTGTQGANLAYP-AGSTQPIRIEPSSSQ-VAEGQTLDLNCV 2363

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            + G+    V W+K G  L  P ++           LR+ +A P D G+Y C    S+  V
Sbjct: 2364 VPGQSHAQVTWHKRGGSL--PVRH-----QTHGSLLRLYQASPADSGEYVCRVLGSS--V 2414

Query: 4705 TVAAKLKVTQPDQADNLPAL--TPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWLRE 4757
             + A + VT  + A ++PAL  TP   I      V EGQ       +  +    + W + 
Sbjct: 2415 PLEASVLVTI-EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKR 2473

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            G  +P        H+ + + L +      D+G + CR   ++G  E S  + ++ +
Sbjct: 2474 GGSLPAR------HQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2523



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 102/427 (23%), Positives = 166/427 (38%), Gaps = 44/427 (10%)

Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
            AQ + +VV      + PP    +     V E +         G     + WYR    +  
Sbjct: 2034 AQARMQVVVLSASDASPPGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLP- 2092

Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513
             P  Q+H     S L + QV   DS  +    EN  G  + S  + V      G      
Sbjct: 2093 -PHTQVHG----SRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPV 2147

Query: 4514 PSFT----LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
            P  T    +   + +V  GQ + L+  V G     V W K G  +    R+   +  G+ 
Sbjct: 2148 PGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RH---QTHGSL 2202

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
             L + +  P DSG+Y C  + ++G    +A  +V++ A+   P P       PP  IE  
Sbjct: 2203 -LRLHQVTPADSGEYVCHVVGTSGPL--EASVLVTIEASVI-PGP------IPPVRIES- 2251

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
                VAEGQ ++ SC + G+    V WYK    +      + SR      L I +A P D
Sbjct: 2252 SSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSR------LYIFQASPAD 2305

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADNLPALTPLR----DIVVYEGQPAQFKTQI 4744
             G Y C A N     ++   +  TQ  + A    +  P+R       V EGQ       +
Sbjct: 2306 AGQYVCRASNGM-EASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVV 2364

Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
              +    + W + G  +P      + H+ + ++L +      D+G + CR   ++  +E 
Sbjct: 2365 PGQSHAQVTWHKRGGSLP------VRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEA 2418

Query: 4805 SAKLVVK 4811
            S  + ++
Sbjct: 2419 SVLVTIE 2425



 Score = 78.6 bits (185), Expect = 5e-13
 Identities = 95/410 (23%), Positives = 160/410 (39%), Gaps = 52/410 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP  T   +   V   E  + +    G P    +W R    +           +   +L 
Sbjct: 3298 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPG------RATARNELLH 3351

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP----PSFTLTAQNVNV 4525
              +   EDS  +     N+ G+A+  A L+V+          +P    P+  +T Q    
Sbjct: 3352 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3411

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            + G  V     V   +   + W K G ++ P   + +  +DG   +  L+   Q  G Y 
Sbjct: 3412 SIGASVEFHCAVPSDQGTQLRWFKEGGQLPPG--HSV--QDGVLRIQNLDQSCQ--GTYI 3465

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI--VAEGQAIEFS 4643
            C A    G+A+  A+ V+                 A P ++  ++  +  V  G A+EF 
Sbjct: 3466 CQAHGPWGKAQASAQLVIQ----------------ALPSVLINIRTSVQTVVVGHAVEFE 3509

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C  +G P P V W K    ++P              +RI+     D G Y+C A N+AG 
Sbjct: 3510 CLALGDPKPQVTWSKVGGHLRP------GIVQSGGVVRIAHVELADAGQYRCTATNAAG- 3562

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             T +  L + Q      LP ++  +++ V  G  A F    +    P I W +    +P 
Sbjct: 3563 TTQSHVLLLVQA-----LPQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLP- 3616

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             PD ++     N +L++ +   +D GT+ C AT   G+V+  A L V  +
Sbjct: 3617 -PDSRL----ENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3661



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 74/305 (24%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V P+  + + +  V  GQ + L+  V G     V W K G  +    R+++    G+  L
Sbjct: 2435 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV---HGS-RL 2488

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             +L+  P DSG+Y C  + S+G    +A  +V++   + +         A P  IE    
Sbjct: 2489 RLLQVTPADSGEYVCRVVGSSGTQ--EASVLVTI---QQRLSGSHSQGVAYPVRIES-SS 2542

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
              +A G  ++ +C +  +   T+ WYK G  L  PS++  +        LRI +  P D 
Sbjct: 2543 ASLANGHTLDLNCLVASQAPHTITWYKRGGSL--PSRHQIVGS-----RLRIPQVTPADS 2595

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQIT 4745
            G+Y C   N AG    +  + + Q   + ++P+++P   I      V EGQ       + 
Sbjct: 2596 GEYVCHVSNGAGSRETSLIVTI-QGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 2654

Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             + +  I W + G  +P        H+ + + L +      D+G + CRA      +E S
Sbjct: 2655 RQPQAIITWYKRGGSLPSR------HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEAS 2708

Query: 4806 AKLVV 4810
              + V
Sbjct: 2709 IVISV 2713



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 79/354 (22%), Positives = 146/354 (41%), Gaps = 33/354 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L I QV   DS  +     N  G+ + S  + ++         + PP   + + +  V
Sbjct: 2583 SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPP-IRIESSSPTV 2641

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L+  V       + W K G  +    R+   +  G++ L + +    DSG+Y 
Sbjct: 2642 VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RH---QTHGSH-LRLHQMSVADSGEYV 2695

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N+      +A  V+S+  +   P   +   ++ P  IE      VAEG+ ++ +C 
Sbjct: 2696 CRANNNIDAL--EASIVISVSPSAGSP---SAPGSSMPIRIESSSSH-VAEGETLDLNCV 2749

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            + G+    V W+K    +      + SR      LR+    P D G+Y C    S+G + 
Sbjct: 2750 VPGQAHAQVTWHKRGGSLPSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLE 2803

Query: 4706 VAAKLKV-TQPDQADNLPA---LTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
             +  + +      A ++PA     P+R       V EGQ    K  +  +    + W + 
Sbjct: 2804 ASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKR 2863

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G  +P        H+ +  +L +      D+G ++C+ T ++G +E S  + ++
Sbjct: 2864 GGNLPAR------HQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIE 2911



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 87/362 (24%), Positives = 140/362 (38%), Gaps = 34/362 (9%)

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP---PSF 4516
            H  +  S L +  V   DS  +        G  + S  + +E           P   P  
Sbjct: 2770 HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPI 2829

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
             +   +  V  GQ + L   V G     V W K G  +    R+++    G   L + + 
Sbjct: 2830 RIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPA--RHQV---HGPL-LRLNQV 2883

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
             P DSG+Y C    S+G    +A  +V++  +   P P    A   P  IE      V E
Sbjct: 2884 SPADSGEYSCQVTGSSGTL--EASVLVTIEPSSPGPIPAPGLAQ--PIYIEASSSH-VTE 2938

Query: 4637 GQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            GQ ++ +C + G+    V WYK G  L  P+++           LR+    P D G+Y C
Sbjct: 2939 GQTLDLNCVVPGQAHAQVTWYKRGGSL--PARH-----QTHGSQLRLHLVSPADSGEYVC 2991

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQITSKIKP 4750
             A +  G    A+      P +  +    +P+  I      V +GQ A FK  I     P
Sbjct: 2992 RAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAP 3051

Query: 4751 -TIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +++W      + +      +H   N +++ I  T   + GT+ C A+ A G  ++   L
Sbjct: 3052 ISLEWKTRNQELEDN-----VHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNL 3106

Query: 4809 VV 4810
             V
Sbjct: 3107 SV 3108



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 30/292 (10%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V  GQ + L+  V G     V W K G  +   +R+   +  G+  L + +A P DSG+Y
Sbjct: 2352 VAEGQTLDLNCVVPGQSHAQVTWHKRGGSLP--VRH---QTHGSL-LRLYQASPADSGEY 2405

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C  + S+     +A  +V++     +P     A    P +        VAEGQ ++ +C
Sbjct: 2406 VCRVLGSS--VPLEASVLVTI-----EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNC 2458

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             + G+    V W+K    +        SR      LR+ +  P D G+Y C    S+G  
Sbjct: 2459 LVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSGEYVCRVVGSSGTQ 2512

Query: 4705 TVAAKLKVTQ-----PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + + Q       Q    P         +  G        + S+   TI W + G 
Sbjct: 2513 EASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGG 2572

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P        H+   + L I      D+G + C  +  AG  ETS  + ++
Sbjct: 2573 SLPSR------HQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2618



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 56/177 (31%), Positives = 74/177 (41%), Gaps = 21/177 (11%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G    F+C   G P P+VTW      +R       +V   G   + I +V L+D+G 
Sbjct: 3500 VVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG-----IVQSGG--VVRIAHVELADAGQ 3552

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A N +G T     L V    Q+  P+ V       V  G   V    A G PTP I
Sbjct: 3553 YRCTATNAAGTTQSHVLLLVQALPQISMPQEV------RVPAGSAAVFPCIASGYPTPDI 3606

Query: 523  TWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +W K DG   +P P+ R+      + L +P  +  DA  Y CTA N  G     A L
Sbjct: 3607 SWSKLDG--SLP-PDSRLEN----NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHL 3656



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 102/486 (20%), Positives = 169/486 (34%), Gaps = 54/486 (11%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A+F     G+PTP + WT      +           Q     L +  + P D+ +Y 
Sbjct: 1880 GQLAEFRCSATGSPTPTLEWTGGPGGQLPAKA-------QIHGGILRLPAVEPTDQAQYL 1932

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH--KAYGTQGYTTEQSRQ 203
            C A +  G+ +    +   G               H   TV    +A G    T    ++
Sbjct: 1933 CRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE 1992

Query: 204  TQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
               +     ++ +      +         +  F   +     G +  ++   +  S    
Sbjct: 1993 GGSLPPQARSERTDIATLLIPAIT---TADAGFYLCVATSPAGTAQARMQVVV-LSASDA 2048

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP +  +  +  + EG        ++G+   +VTW++ G  L     H   T  + + L
Sbjct: 2049 SPPGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSL---PPH---TQVHGSRL 2102

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            R+     +DSG Y    EN +G    S  ++V   T S          T         RI
Sbjct: 2103 RLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHS------GPSYTPVPGSTRPIRI 2156

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            E S   +A             EG+    +C V G+ + +VTW      +   +       
Sbjct: 2157 EPSSSHVA-------------EGQTLDLNCVVPGQAHAQVTWHKRGGSLPARH------- 2196

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--STLN 501
            ++    L +  VT +DSG   C     SG       L  IE   +  P    R   S+  
Sbjct: 2197 QTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSST 2255

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + L+    G    ++TW K G  +    ++R       S L I +A  +DA  Y
Sbjct: 2256 VAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVR------GSRLYIFQASPADAGQY 2309

Query: 562  QCTAQN 567
             C A N
Sbjct: 2310 VCRASN 2315



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 45/177 (25%), Positives = 77/177 (43%), Gaps = 11/177 (6%)

Query: 395  VKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            V+V  +R  V  G+  R  CR  G P   +TW    R+       +     +    L+I 
Sbjct: 1958 VQVSPERTQVHAGRTVRLYCRAAGVPSATITW----RKEGGSLPPQARSERTDIATLLIP 2013

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
             +T +D+G   CVA + +G    + ++ V+       P      S+ +V EG+ + LN  
Sbjct: 2014 AITTADAGFYLCVATSPAGTAQARMQVVVLSASDASPPGVKIESSSPSVTEGQTLDLNCV 2073

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G+   ++TW + G  + P      HT    S L +P+   +D+  Y C  +N +G
Sbjct: 2074 VAGSAHAQVTWYRRGGSLPP------HTQVHGSRLRLPQVSPADSGEYVCRVENGSG 2124



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 112/531 (21%), Positives = 179/531 (33%), Gaps = 67/531 (12%)

Query: 52   VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
            +E+SG    +    PG   P   E    ++R A+G     +  + G     V+W ++   
Sbjct: 2810 IEASGS-SAVHVPAPGGAPPIRIEP--SSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGN 2866

Query: 112  LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXX 171
            L            Q     L + Q+ P D GEY+C      G    SV +  E       
Sbjct: 2867 LPA--------RHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPI 2918

Query: 172  XXXXXXXYRHVSETVEHKAYGTQ---GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEY 228
                     ++  +  H   G               Q   Y  G    +           
Sbjct: 2919 PAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRL 2978

Query: 229  RLLREVSFRESITKRYVG---ESDVQISTEIDRSLGP---VSPPKIAQKPRNSKLQEGAD 282
             L+      E + +   G   E +   +  +  S G    +  P I+  P +S +Q+G D
Sbjct: 2979 HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQD 3038

Query: 283  AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            A F+  +     P    +K   + +  N H    + N + + +  T+ S+ G Y      
Sbjct: 3039 ASFKCLIHDGAAPISLEWKTRNQELEDNVH---ISPNGSIITIVGTRPSNHGTYR----- 3090

Query: 343  PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
               C+ ++ Y   +S     V    +                +S     P +VKV     
Sbjct: 3091 ---CVASNAYGVAQSVVNLSVHGPPT----------------VSVLPEGPVWVKV----- 3126

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHA-LMITNVTLSDS 460
               GK    +C   G P     W  I+    + +     L++   +HA L I++   SD+
Sbjct: 3127 ---GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMD---SHAVLQISSAKPSDA 3180

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
            G   C+A+N  G    Q  + V        AP+     + L V  G    L   A G+P 
Sbjct: 3181 GTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPA 3240

Query: 520  PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P I W K   P+     L         TL IPR    D+  Y C A + AG
Sbjct: 3241 PTIHWSKLRSPLPWQHRLE------GDTLIIPRVAQQDSGQYICNATSPAG 3285



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 80/315 (25%), Positives = 109/315 (34%), Gaps = 41/315 (13%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP     P ++ +Q G   Q Q    G P     W + G  L          T  +  L
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGR------ATARNELL 3350

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG Y     N  G       L V+ P  S          T T Q       
Sbjct: 3351 HFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ------- 3403

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
                  + PQ     + + +  G    F C V      ++ WF    Q+     H +   
Sbjct: 3404 ------VTPQL----ETKSI--GASVEFHCAVPSDQGTQLRWFKEGGQLPP--GHSV--- 3446

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            + G   L I N+  S  G   C A    G+     +L VI+    V      R S   V 
Sbjct: 3447 QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQASAQL-VIQALPSVLINI--RTSVQTVV 3501

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             G  V     A+G P P++TW K G  + P     I   GG   + I   + +DA  Y+C
Sbjct: 3502 VGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGG--VVRIAHVELADAGQYRC 3555

Query: 564  TAQNVAGSTATRARL 578
            TA N AG+T +   L
Sbjct: 3556 TATNAAGTTQSHVLL 3570



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 115/528 (21%), Positives = 187/528 (35%), Gaps = 68/528 (12%)

Query: 62   TAGRPGEPSPPIFEQI-FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            +AG P  P   +  +I   ++  A+G        + G     V+W ++          S+
Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG--------SL 2767

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXX 178
              + QT    L +  + P D GEY C      G  EA   V I+  G             
Sbjct: 2768 PSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAP 2827

Query: 179  YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV-DTFEYRLLR--EVS 235
               +  +    A   +G T +        A+   T H    +          LLR  +VS
Sbjct: 2828 PIRIEPSSSRVA---EGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVS 2884

Query: 236  FRES--ITKRYVGES---DVQISTEIDRSL-GPVSPPKIAQ----KPRNSKLQEGADAQF 285
              +S   + +  G S   +  +   I+ S  GP+  P +AQ    +  +S + EG     
Sbjct: 2885 PADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2944

Query: 286  QVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               + G    +VTW+K G  L    +H+   TH  + LR+     +DSG Y   A +  G
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSL--PARHQ---THG-SQLRLHLVSPADSGEYVCRAASGPG 2998

Query: 346  CIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTE 405
                + +     P+E      RS  I+      T                       V +
Sbjct: 2999 PEQEASFTVTVPPSEGSSYRLRSPVISIDPPSST-----------------------VQQ 3035

Query: 406  GKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
            G+   F C +     P  + W   ++++ D+ +    ++ +G+  + I     S+ G   
Sbjct: 3036 GQDASFKCLIHDGAAPISLEWKTRNQELEDNVH----ISPNGS-IITIVGTRPSNHGTYR 3090

Query: 465  CVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
            CVA N  G       L+V     V V P+       + V+ G+ V L   + G P     
Sbjct: 3091 CVASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVWVKVGKAVTLECVSAGEPRSSAR 3145

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            W +         +         + L I  AK SDA  Y C AQN  G+
Sbjct: 3146 WTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGT 3193



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 5/133 (3%)

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            N  L I NV LSD+G   C   N          L+V     + AP        L V+ G+
Sbjct: 1822 NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQ 1881

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
                   A G+PTP + W       +P  + +IH  GG   L +P  + +D A Y C A 
Sbjct: 1882 LAEFRCSATGSPTPTLEWTGGPGGQLP-AKAQIH--GG--ILRLPAVEPTDQAQYLCRAH 1936

Query: 567  NVAGSTATRARLY 579
            + AG    RA L+
Sbjct: 1937 SSAGQQVARAVLH 1949



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 12/176 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G++  F C  TG P P + W             K  ++      L +  V  +D   
Sbjct: 1877 VQPGQLAEFRCSATGSPTPTLEWTGGPG---GQLPAKAQIHGG---ILRLPAVEPTDQAQ 1930

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A + +G+   +  L+V        P+         V  G  V L  RA G P+  I
Sbjct: 1931 YLCRAHSSAGQQVARAVLHV---HGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATI 1987

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            TW+K+G  + P       TD   +TL IP    +DA +Y C A + AG+   R ++
Sbjct: 1988 TWRKEGGSLPPQARSE-RTD--IATLLIPAITTADAGFYLCVATSPAGTAQARMQV 2040



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 53/231 (22%), Positives = 82/231 (35%), Gaps = 20/231 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H++          L +L     DSG
Sbjct: 2448 VAEGQTL--DLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSG 2499

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CR     G  E SV +    +  G   +   +   IE     L +G +    C V  
Sbjct: 2500 EYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVA- 2558

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
                   I WY  G  +   +R + V       L I      DSGEYVC   N  G   T
Sbjct: 2559 -SQAPHTITWYKRGGSL--PSRHQIVGSR----LRIPQVTPADSGEYVCHVSNGAGSRET 2611

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
               +   G G  ++ S+ P    +      ++G         + +P   IT
Sbjct: 2612 SLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIIT 2662



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 14/173 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + +GQ A ++  LI  G   + +EW    + +E +  I    +    ++ I+GT+ ++ G
Sbjct: 3033 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHG 3087

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
            TY C A+N +G A+  V L     S    P  +   +    +K G++   EC  V   +P
Sbjct: 3088 TYRCVASNAYGVAQSVVNL-----SVHGPPTVSVLPEGPVWVKVGKAVTLEC--VSAGEP 3140

Query: 3180 DMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                 W   +  P +   R   + D    VL I+  +  D+G YVC A N  G
Sbjct: 3141 RSSARWTRISSTPAKLEQRTYGLMD-SHAVLQISSAKPSDAGTYVCLAQNALG 3192



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 8/140 (5%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I   + +D+GTY C  +N +   + +  L          P  + H   +  ++ GQ 
Sbjct: 1824 ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT-VQPGQL 1882

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A F C+      P   +EW   G P     ++   +     +L +   +  D  +Y+CRA
Sbjct: 1883 AEFRCSAT--GSPTPTLEW--TGGP---GGQLPAKAQIHGGILRLPAVEPTDQAQYLCRA 1935

Query: 3227 YNKYGEDFTRATINCYGKGG 3246
            ++  G+   RA ++ +G GG
Sbjct: 1936 HSSAGQQVARAVLHVHGGGG 1955



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 80/320 (25%), Positives = 123/320 (38%), Gaps = 52/320 (16%)

Query: 261  GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
            G   P +I  +P +S++ EG        + G    +VTW K G  L    +H+   TH  
Sbjct: 2338 GSTQPIRI--EPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSL--PVRHQ---THG- 2389

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
            + LR+     +DSG Y       +  +  S  + +E P  S      +  +T T      
Sbjct: 2390 SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVP----ALGVTPTV----- 2439

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
             RIE S   +A             EG+    +C V G+ + +VTW      +     H++
Sbjct: 2440 -RIESSSSQVA-------------EGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV 2483

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGE------TAFQCRLNVIEKEQVVAPKFV 494
                 G+  L +  VT +DSG   C     SG          Q RL+    + V  P  +
Sbjct: 2484 ----HGSR-LRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRI 2538

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
            E  S+ ++  G  + LN          ITW K G  +    ++        S L IP+  
Sbjct: 2539 ES-SSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI------VGSRLRIPQVT 2591

Query: 555  ASDAAWYQCTAQNVAGSTAT 574
             +D+  Y C   N AGS  T
Sbjct: 2592 PADSGEYVCHVSNGAGSRET 2611



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 60/246 (24%), Positives = 96/246 (39%), Gaps = 42/246 (17%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E TI     +PP +   + ++  V  G  V   C     G P +   W   G       R
Sbjct: 3288 EATIILHVESPP-YATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLP--GR 3342

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
                N+     L  +     D+G Y CR TNK GSA   A++        +  + +P G 
Sbjct: 3343 ATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGS 3398

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            +                   P V   P    Q+++ ++  S  V F C V   +  +LR 
Sbjct: 3399 T-------------------PTVQVTP----QLETKSIGAS--VEFHCAVPSDQGTQLR- 3432

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             W++ G  LP GH   +V D G + +  L    +  G YIC+A   +G+    A +  + 
Sbjct: 3433 -WFKEGGQLPPGH---SVQD-GVLRIQNLDQSCQ--GTYICQAHGPWGKAQASAQLVIQA 3485

Query: 3924 LPDIIL 3929
            LP +++
Sbjct: 3486 LPSVLI 3491



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 11/125 (8%)

Query: 4583 KYECVAINSAGEA--RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQA 4639
            ++ CV+ N    A   CD E         D P    +    PP+++ P ++ I A  GQ 
Sbjct: 372  QFRCVSTNMCIPASFHCDEE--------SDCPDRSDEFGCMPPQVVTPPRESIQASRGQT 423

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            + F+C  +G P P + W      I       ++      TL I +    D+G Y C A N
Sbjct: 424  VTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMN 483

Query: 4700 SAGRV 4704
            + G V
Sbjct: 484  ARGMV 488



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 24/72 (33%), Positives = 35/72 (48%)

Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           ++    G+ V     A+G PTP I W+ +   I  +P + + ++GG  TL I   K SD 
Sbjct: 415 SIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQ 474

Query: 559 AWYQCTAQNVAG 570
             Y C A N  G
Sbjct: 475 GAYTCEAMNARG 486



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 42/155 (27%), Positives = 65/155 (41%), Gaps = 18/155 (11%)

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
            DQ   + WF  G  +   H ++        VL I     +  GTY C+A   WG+A+ S 
Sbjct: 3426 DQGTQLRWFKEGGQLPPGHSVQDG------VLRIQNLDQSCQGTYICQAHGPWGKAQASA 3479

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +L  +           T +Q +     G +  FEC  + + DP  ++ W   G  +R   
Sbjct: 3480 QL-VIQALPSVLINIRTSVQTV---VVGHAVEFEC--LALGDPKPQVTWSKVGGHLRPG- 3532

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                V   G  V+ IA+ +  D+G+Y C A N  G
Sbjct: 3533 ---IVQSGG--VVRIAHVELADAGQYRCTATNAAG 3562



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 58/278 (20%), Positives = 105/278 (37%), Gaps = 24/278 (8%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A       G+P P + W++ ++PL   ++         GD +L+I ++   D G+Y 
Sbjct: 3226 GHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLE-------GD-TLIIPRVAQQDSGQYI 3277

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQ 205
            C A +  G A  ++ +  E                  +  ++  A+GT   T + SR   
Sbjct: 3278 CNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 3337

Query: 206  KVAYTNGTDHSSTDDFK----VDTFEY--RLLREVSFRESITKRYVGESDVQISTEIDRS 259
             +     T  +    F+     D+  Y  R+  +V   E+  +  V      +      S
Sbjct: 3338 SLP-GRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPA---TS 3393

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            +   S P +   P+      GA  +F   +  +   ++ WFK G +L     H +     
Sbjct: 3394 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDQGTQLRWFKEGGQL--PPGHSV----Q 3447

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
               LR++N  +S  G Y   A  P G    S  L +++
Sbjct: 3448 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQA 3485



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 2377 VFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSM 2436
            V T P ++I     GQT  F C  + +G PT  + W  N   I    R+T T + G  ++
Sbjct: 408  VVTPPRESIQ-ASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464

Query: 2437 TISHVRDEDEGVYMCRASNLLG 2458
             I  V++ D+G Y C A N  G
Sbjct: 465  IIRDVKESDQGAYTCEAMNARG 486



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 56/240 (23%), Positives = 91/240 (37%), Gaps = 44/240 (18%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            ++P +   +    +++ GE    +     T  P L  +W   G SL   +  R       
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARN------ 3347

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537
             +L      PEDSG Y CR  N  G A   A + VQG    +  + +P G   T+     
Sbjct: 3348 ELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ---- 3403

Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
                      +TP+ E+               S  +S  F C  +P +D   ++ WF  G
Sbjct: 3404 ----------VTPQLET--------------KSIGASVEFHC-AVP-SDQGTQLRWFKEG 3437

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
              L  G  V+        +L I  + Q   G Y C+A    G+A  S +L ++    +++
Sbjct: 3438 GQLPPGHSVQD------GVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLI 3491



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + S +  G     + W+  G ++ A H++R    +      I      D+G
Sbjct: 2256 VAEGQTL--DLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLY------IFQASPADAG 2307

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CRA+N   +A I+V +     +    P  +T    IE     + +GQ+    C VVP
Sbjct: 2308 QYVCRASNGM-EASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC-VVP 2365

Query: 3176 VDDPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                  ++ W+  G   P+RH T           +L +      DSGEYVCR
Sbjct: 2366 -GQSHAQVTWHKRGGSLPVRHQTHGS--------LLRLYQASPADSGEYVCR 2408



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 59/239 (24%), Positives = 87/239 (36%), Gaps = 19/239 (7%)

Query: 4581 SGKYECVAINSAGEARCDAEC---VVSLPATKD-KPKPQTKAANAPPEIIEPLKDKIVAE 4636
            +G Y C A       +   +C    V  P+ +  +  P+T  A    E+  P +  IV +
Sbjct: 1633 AGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEV-HPARS-IVPQ 1690

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G +    C++ G P     W + D    PS   Q  + ++   L      P D G Y C 
Sbjct: 1691 GGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSE---LHFPSVQPSDAGVYICT 1747

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP-TIQWL 4755
              N     T  A+L VT+         +   R   V  G    F     SK    T+ W 
Sbjct: 1748 CRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWT 1807

Query: 4756 R--EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            R   G L     DF       N +L I N    D GT+ C  +      + +A L V++
Sbjct: 1808 RLHNGKLPTRAMDF-------NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQA 1859



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 25/181 (13%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    +  ++P G     + W   G  + A H++         +L +      DSG
Sbjct: 2838 VAEGQTLDLKC-VVP-GQAHAQVTWHKRGGNLPARHQVHGP------LLRLNQVSPADSG 2889

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKP----RFTTHIQ-NIEGLKDGQSAHFECTVV 3174
             YSC+ T   G  E SV +     S G  P        +I+ +   + +GQ+    C VV
Sbjct: 2890 EYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VV 2948

Query: 3175 PVDDPDMKIEWYHNG--QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P      ++ WY  G   P RH T            L +      DSGEYVCRA +  G 
Sbjct: 2949 P-GQAHAQVTWYKRGGSLPARHQTHGSQ--------LRLHLVSPADSGEYVCRAASGPGP 2999

Query: 3233 D 3233
            +
Sbjct: 3000 E 3000



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 6/116 (5%)

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADN---LP--ALTPLRD-IVVYEGQPAQFKTQITS 4746
            ++CV+ N     +     +   PD++D    +P   +TP R+ I    GQ   F      
Sbjct: 373  FRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIG 432

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
               P I W      IP  P   +  EG    L+I +  E D G +TC A  A G V
Sbjct: 433  VPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMV 488



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 17/188 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W+  G ++ A H+           L +      DSG
Sbjct: 2936 VTEGQTL--DLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQ------LRLHLVSPADSG 2987

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE----GLKDGQSAHFECTVVP 3175
             Y CRA +  G  + +     V  S+G   R  + + +I+     ++ GQ A F+C +  
Sbjct: 2988 EYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHD 3047

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               P + +EW    Q +  +  I         ++ I  T+  + G Y C A N YG   +
Sbjct: 3048 GAAP-ISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHGTYRCVASNAYGVAQS 3102

Query: 3236 RATINCYG 3243
               ++ +G
Sbjct: 3103 VVNLSVHG 3110



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/306 (24%), Positives = 118/306 (38%), Gaps = 46/306 (15%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P +  +  +S++ EG        ++G    +VTW K G  L    +H++    + + LR+
Sbjct: 2437 PTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV----HGSRLRL 2490

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
                 +DSG Y         C V       E+     +Q + S   + +Q      RIE 
Sbjct: 2491 LQVTPADSGEYV--------CRVVGSSGTQEASVLVTIQQRLSG--SHSQGVAYPVRIES 2540

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            S  +LA              G     +C V  +    +TW+     +     H+I+ +  
Sbjct: 2541 SSASLA-------------NGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGSR- 2584

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQV--VAPKFVERFSTLN 501
                L I  VT +DSG   C   N +G  ET+    +       V  V+P      S+  
Sbjct: 2585 ----LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPT 2640

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + LN      P   ITW K G   +P+   R  T G  S L + +   +D+  Y
Sbjct: 2641 VVEGQTLDLNCVVARQPQAIITWYKRG-GSLPS---RHQTHG--SHLRLHQMSVADSGEY 2694

Query: 562  QCTAQN 567
             C A N
Sbjct: 2695 VCRANN 2700



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 55/212 (25%), Positives = 79/212 (37%), Gaps = 19/212 (8%)

Query: 368  SQYITDTQQRETEERIEISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
            +Q    T Q++ E  ++    A  APQ      +  V  G      C  TG P P + W 
Sbjct: 3187 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW- 3245

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
             +  +    + H++     G+  L+I  V   DSG   C A + +G       L+V  + 
Sbjct: 3246 -SKLRSPLPWQHRL----EGD-TLIIPRVAQQDSGQYICNATSPAGHAEATIILHV--ES 3297

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
               A    E  S   V+ GE V L   A GTP     W + G  +      R        
Sbjct: 3298 PPYATTVPEHAS---VQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR------NE 3348

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             L   RA   D+  Y+C   N  GS    A+L
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQL 3380



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 8/108 (7%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            + P + T +    S+   ET + +C LA  G P +  +W   G  L    R T   +   
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQC-LAH-GTPPLTFQWSRVGSSL--PGRATARNEL-- 3349

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP 4078
              ++F    PEDSG Y CR TN  G  E  A +   G PG +  + +P
Sbjct: 3350 --LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIP 3395



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 39/165 (23%), Positives = 61/165 (36%), Gaps = 12/165 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S  I W   G ++    R        +  L I    T D+G Y C AT+  G A+  
Sbjct: 1981 GVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCVATSPAGTAQAR 2037

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
            +++  +  S    P       +   + +GQ+    C V        ++ WY  G  +   
Sbjct: 2038 MQVVVLSASDASPPGVKIESSS-PSVTEGQTLDLNCVVA--GSAHAQVTWYRRGGSLPPH 2094

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
            T++          L +      DSGEYVCR  N  G      T++
Sbjct: 2095 TQVHGSR------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2133



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 46/153 (30%), Positives = 61/153 (39%), Gaps = 23/153 (15%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+  G ++ + H+I      G   L I      DSG Y C  +N  G  E S+ +   
Sbjct: 2565 ITWYKRGGSLPSRHQI-----VGSR-LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2618

Query: 3142 DKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQ--PMRHS 3195
                   P  +  I+ IE     + +GQ+    C V     P   I WY  G   P RH 
Sbjct: 2619 GSGSSHVPSVSPPIR-IESSSPTVVEGQTLDLNCVVAR--QPQAIITWYKRGGSLPSRHQ 2675

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            T     S      + +A     DSGEYVCRA N
Sbjct: 2676 TH---GSHLRLHQMSVA-----DSGEYVCRANN 2700



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 29/218 (13%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            +I W+  G ++ + H+    +      L +      DSG Y CRA N     E S+ +  
Sbjct: 2660 IITWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVIS- 2712

Query: 3141 VDKSKG--QKPRFTTHIQ---NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG--QPMR 3193
            V  S G    P  +  I+   +   + +G++    C VVP      ++ W+  G   P  
Sbjct: 2713 VSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC-VVP-GQAHAQVTWHKRGGSLPSH 2770

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATINCYGKGGVYLES 3251
            H TR           L + +    DSGEYVCR     G  E     TI   G   V++ +
Sbjct: 2771 HQTRGSR--------LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPA 2822

Query: 3252 LQPDSLAKIR-ELESLQGAQQQTPSTPSAEPPKFITQI 3288
              P     IR E  S + A+ QT       P +   Q+
Sbjct: 2823 --PGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQV 2858



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQ 3165
            VL+I   K +D+GTY C A N  G A+  V++  VD             +  E  ++ G 
Sbjct: 3169 VLQISSAKPSDAGTYVCLAQNALGTAQKQVEV-IVDTGAMAPGAPQVQAEEAELTVEAGH 3227

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A   C+      P   I W     P+    R++   D     L I      DSG+Y+C 
Sbjct: 3228 TATLRCSA--TGSPAPTIHWSKLRSPLPWQHRLE--GD----TLIIPRVAQQDSGQYICN 3279

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
            A +  G     ATI  + +   Y  ++   +  +  E   LQ     TP
Sbjct: 3280 ATSPAGH--AEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTP 3326



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/52 (42%), Positives = 27/52 (51%)

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAF 2996
            I W  N   +    R  +TS+ G  TL + DV E D G YTC+A N RG  F
Sbjct: 438  INWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVF 489



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 52/218 (23%), Positives = 76/218 (34%), Gaps = 13/218 (5%)

Query: 385  ISEKALAPQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWFIND-RQIRDDYNHKILV 442
            + E   AP  V+V   R +  +G      C+V+G P     W   D R +      +   
Sbjct: 1669 LPETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQG 1728

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +E     L   +V  SD+GV  C  RN       +  L V E         VE   + +V
Sbjct: 1729 SE-----LHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSV 1783

Query: 503  REGEPVVLNARAVG-TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            R G  V     A   +P   + W +     + N +L          L I   + SDA  Y
Sbjct: 1784 RPGADVTFICTAKSKSPAYTLVWTR-----LHNGKLPTRAMDFNGILTIRNVQLSDAGTY 1838

Query: 562  QCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPT 599
             CT  N+       A L+             +H P+ T
Sbjct: 1839 VCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT 1876



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 56/276 (20%), Positives = 97/276 (35%), Gaps = 14/276 (5%)

Query: 85   QGGNAKFEGKLRGNPTPV-VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
            QG +A F+  +     P+ + W  +   L E N +        G + + I    P + G 
Sbjct: 3035 QGQDASFKCLIHDGAAPISLEWKTRNQEL-EDNVHI----SPNGSI-ITIVGTRPSNHGT 3088

Query: 144  YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR-HVSETVEHKAYGTQGYTTEQSR 202
            Y C A N YG A   V +   G              +   + T+E  + G    +   +R
Sbjct: 3089 YRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTR 3148

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262
             +   A      +   D   V         +      + +  +G +  Q+   +D     
Sbjct: 3149 ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMA 3208

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
               P++  +     ++ G  A  +   +G+P P + W K    L   ++ E        T
Sbjct: 3209 PGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLE------GDT 3262

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L +    + DSG Y   A +P G    +  L VESP
Sbjct: 3263 LIIPRVAQQDSGQYICNATSPAGHAEATIILHVESP 3298



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 12/117 (10%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            T+  + +  +AL PQ + + Q+  V  G    F C  +G P P+++W   D  +  D   
Sbjct: 3564 TQSHVLLLVQAL-PQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPD--- 3618

Query: 439  KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
                +   N+ LM+ +V   D+G   C A N+ G+      L V E+   V P F +
Sbjct: 3619 ----SRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER---VVPYFTQ 3668



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 1/84 (1%)

Query: 265 PPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           PP++   PR S +   G    F     G P P + W  N   + +  +  + +     TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464

Query: 324 RVRNTQKSDSGHYTLLAENPNGCI 347
            +R+ ++SD G YT  A N  G +
Sbjct: 465 IIRDVKESDQGAYTCEAMNARGMV 488



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 55/218 (25%), Positives = 79/218 (36%), Gaps = 27/218 (12%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H+          +L +      DSG
Sbjct: 2163 VAEGQTL--DLNCVVPGQAHAQVTWHKRGGSLPARHQTHGS------LLRLHQVTPADSG 2214

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDD 3178
             Y C      G  E SV L  ++ S    P     I++    + +GQ+    C V     
Sbjct: 2215 EYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA--GQ 2271

Query: 3179 PDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
               ++ WY  G   P RH  R           L I      D+G+YVCRA N      T 
Sbjct: 2272 AHAQVTWYKRGGSLPARHQVRGSR--------LYIFQASPADAGQYVCRASNGMEASITV 2323

Query: 3237 ATINCYGKGGVY-LESLQPDSLAKIRELESLQGAQQQT 3273
                  G    Y   S QP  +    E  S Q A+ QT
Sbjct: 2324 TVTGTQGANLAYPAGSTQPIRI----EPSSSQVAEGQT 2357



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 62/267 (23%), Positives = 97/267 (36%), Gaps = 46/267 (17%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            DSG Y C AT+  G AE ++ L        + P + T +     ++ G++   +C  +  
Sbjct: 3272 DSGQYICNATSPAGHAEATIILHV------ESPPYATTVPEHASVQAGETVQLQC--LAH 3323

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P +  +W   G  +      +        +L        DSG Y CR  NK G     
Sbjct: 3324 GTPPLTFQWSRVGSSLPGRATARNE------LLHFERAAPEDSGRYRCRVTNKVGSAEAF 3377

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +   G  G                  SL        STP+ +    +T  Q  TK + 
Sbjct: 3378 AQLLVQGPPG------------------SLPATSIPAGSTPTVQ----VTP-QLETKSI- 3413

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356
            G S  F    VP  D   ++ WF  G +LP GH  +        +L I    +   G Y 
Sbjct: 3414 GASVEFHC-AVP-SDQGTQLRWFKEGGQLPPGHSVQD------GVLRIQNLDQSCQGTYI 3465

Query: 3357 CVATNKLGRDSTKANLKCTSKENLILD 3383
            C A    G+    A L   +  +++++
Sbjct: 3466 CQAHGPWGKAQASAQLVIQALPSVLIN 3492



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 636 PPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPQ + P + S+ A  G  + F      +G PT  I W  N   I +  R T     G  
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG 462

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGV 719
           +L +  +   D G YTC A++A G+
Sbjct: 463 TLIIRDVKESDQGAYTCEAMNARGM 487



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
            V T P + I+ +  Q   F    + +G P   + W  N   I +  R+T   + G   L 
Sbjct: 408  VVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 465

Query: 1772 MKYVNPEDSGTYTCRAINELG 1792
            ++ V   D G YTC A+N  G
Sbjct: 466  IRDVKESDQGAYTCEAMNARG 486



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 62/248 (25%), Positives = 93/248 (37%), Gaps = 46/248 (18%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            + + + +     +PP   +E   +  V EG  +  +C V   G    ++ W+  G     
Sbjct: 2037 RMQVVVLSASDASPPGVKIE-SSSPSVTEGQTLDLNCVV--AGSAHAQVTWYRRGGSLPP 2093

Query: 3741 GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800
             ++VH         L +  +   D+GEY CR  N  GS    A IT S     VL     
Sbjct: 2094 HTQVHGSR------LRLPQVSPADSGEYVCRVEN--GSGPKEASITVS-----VLHG--- 2137

Query: 3801 QGMSGEKIKELERGRISDAPKEEPIV-STPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859
                               P   P+  ST P  I    SH V E + +   C V P +  
Sbjct: 2138 ---------------THSGPSYTPVPGSTRPIRIEPSSSH-VAEGQTLDLNC-VVPGQ-A 2179

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKA 3917
              ++ W++ G  LP+ H+       G + L +  V   DSGEY+C  V   G  E     
Sbjct: 2180 HAQVTWHKRGGSLPARHQTH-----GSL-LRLHQVTPADSGEYVCHVVGTSGPLEASVLV 2233

Query: 3918 TISCKKLP 3925
            TI    +P
Sbjct: 2234 TIEASVIP 2241



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + S  P    +  S TV E + +   C V     P+  I WY+ G  LPS H+    +  
Sbjct: 2625 VPSVSPPIRIESSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH-- 2680

Query: 3885 GFVSLDILYVYAEDSGEYICRAVND 3909
                L +  +   DSGEY+CRA N+
Sbjct: 2681 ----LRLHQMSVADSGEYVCRANNN 2701



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 55/239 (23%), Positives = 89/239 (37%), Gaps = 44/239 (18%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            +S   + EG      C V     P   I W+  G  + + H+   +H      L +    
Sbjct: 2636 SSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH------LRLHQMS 2687

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE 2235
              DSG Y+C+A N +           A   +I++      G        A G S  I +E
Sbjct: 2688 VADSGEYVCRANNNID----------ALEASIVISVSPSAGSPS-----APGSSMPIRIE 2732

Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295
                           ++HV EG+T    C V      + ++ ++  G +L S    H T 
Sbjct: 2733 S-------------SSSHVAEGETLDLNCVVPG--QAHAQVTWHKRGGSLPS---HHQTR 2774

Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  L + H  P D+GEY  + + + G   +++ +T+ A GS       P G   IR
Sbjct: 2775 GS---RLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIR 2830



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 390 LAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           + PQ V   ++    + G+   F C   G P P + W +N   I   +    + +E G  
Sbjct: 404 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHI-PSHPRVTVTSEGGRG 462

Query: 449 ALMITNVTLSDSGVVTCVARNKSG 472
            L+I +V  SD G  TC A N  G
Sbjct: 463 TLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 2495 ERRSEEPDREFEKPIFT-QVLTGPSELWEGQHAHYEA-RVVPVGDPSLRFEWYINGVELK 2552
            +  S+ PDR  E      QV+T P E  +           V +G P+    W +N   + 
Sbjct: 389  DEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIP 448

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
               R   T + G  TL I  V  +D G Y C+A+N  G
Sbjct: 449  SHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 1/90 (1%)

Query: 4505 RQGRGGIVPPSF-TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
            R    G +PP   T   +++  + GQ V       G     + W  N   +    R  + 
Sbjct: 397  RSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVT 456

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
             E G  TL+I +    D G Y C A+N+ G
Sbjct: 457  SEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR-NGVPIEASNRLTTMHDFGYVAL 1770
            V  +P   + V   +A   E   +  G+P+    W R +  P +   R   + D  +  L
Sbjct: 3114 VSVLPEGPVWVKVGKAVTLEC--VSAGEPRSSARWTRISSTPAKLEQRTYGLMD-SHAVL 3170

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +    P D+GTY C A N LG A     + V + A
Sbjct: 3171 QISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGA 3206



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 5/99 (5%)

Query: 3035 EPGQQPD--DDTG-RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI 3091
            E    PD  D+ G  PP+  T  ++ +  S GQ   +  + +  G  + +I W  N   I
Sbjct: 390  EESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTF--TCVAIGVPTPIINWRLNWGHI 447

Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
             +  R+      G   L I   K +D G Y+C A N  G
Sbjct: 448  PSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q+GQ A F C LI  G   + +EW    + +ED+  I+         +TI   R  + G
Sbjct: 3033 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGSI----ITIVGTRPSNHG 3087

Query: 2448 VYMCRASNLLG 2458
             Y C ASN  G
Sbjct: 3088 TYRCVASNAYG 3098



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     +++I    G  V F C    +G PT  I+W  N     +  RV   ++ G  
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVA--IGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG 462

Query: 3754 ALDIDYIYARDAGEYTCRATNKWG 3777
             L I  +   D G YTC A N  G
Sbjct: 463  TLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 38/178 (21%)

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            L + H      L +  V P DSG Y C   N  G   TS  + +Q        S H  ++
Sbjct: 2574 LPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG-----SSHVPSV 2628

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
                ++E SS                        PT + EGQ+    C +     P   +
Sbjct: 2629 SPPIRIESSS------------------------PTVV-EGQTLDLNCVVAR--QPQAII 2661

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             WY  G  L S H+   S+      L +  +   DSGEY C+A NN+    +SI ++V
Sbjct: 2662 TWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+ +T      + S GQ+  + C     P P   + W  N   + S  R   +++ G   
Sbjct: 406  PQVVTPPRESIQASRGQTVTFTCVAIGVPTPI--INWRLNWGHIPSHPRVTVTSEGGRGT 463

Query: 1904 LDILTVYGEDSGEYTCKAINNLG 1926
            L I  V   D G YTC+A+N  G
Sbjct: 464  LIIRDVKESDQGAYTCEAMNARG 486



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 12/122 (9%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI--RAGHRYRTTHDF 2164
            + P + T +    +++ G+    +C       P LT  W   G  +  RA  R    H F
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLPGRATARNELLH-F 3352

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
               A        EDSG Y C+ TNK+G A     L V G    +  T  P G     Q+ 
Sbjct: 3353 ERAA-------PEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3405

Query: 2225 AQ 2226
             Q
Sbjct: 3406 PQ 3407



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 6/66 (9%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P L  +W R G  +    R T  ++     L+ +   PEDSG Y CR  N++G A   
Sbjct: 3324 GTPPLTFQWSRVGSSLPG--RATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAF 3377

Query: 1798 STLFVQ 1803
            + L VQ
Sbjct: 3378 AQLLVQ 3383



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 10/111 (9%)

Query: 3825 IVSTPPKFITQIKS--HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            ++   P  +  I++   TV     V FEC      DPK ++ W + G     GH    + 
Sbjct: 3482 VIQALPSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GHLRPGIV 3534

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
              G V + I +V   D+G+Y C A N  G   +   +  + LP I +  +V
Sbjct: 3535 QSGGV-VRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEV 3584



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 10/110 (9%)

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +EP   +  +  +  V ++  S+   V+EG+ + L C +   G    +V W   G S+  
Sbjct: 2424 IEPAGSVPALGVTPTVRIE--SSSSQVAEGQTLDLNCLVA--GQAHAQVTWHKRGGSLP- 2478

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             +R + +       L ++  T AD+GEY  R V   G+   S +V + +R
Sbjct: 2479 -ARHQVHGS----RLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2523



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 53/231 (22%), Positives = 77/231 (33%), Gaps = 45/231 (19%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P   +     +VAE Q    +   +  G    +V W + G        L   H      L
Sbjct: 2437 PTVRIESSSSQVAEGQT--LDLNCLVAGQAHAQVTWHKRG------GSLPARHQVHGSRL 2488

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +  V P DSG Y CR +   G    S  + +Q +    L   H   +    ++E SS  
Sbjct: 2489 RLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR----LSGSHSQGVAYPVRIESSS-- 2542

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
                                     L+ G +    C +     P+  + WY  G  L S 
Sbjct: 2543 -----------------------ASLANGHTLDLNCLVASQA-PH-TITWYKRGGSLPSR 2577

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            H+   S       L I  V   DSGEY C   N  G   +S+ + +Q   S
Sbjct: 2578 HQIVGSR------LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2622



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 1568 DMVDEVTTQAP-ICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF 1626
            D  DE     P + T   ++++   GQ   F    + +   T  + W  N   + S  R 
Sbjct: 396  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFT--CVAIGVPTPIINWRLNWGHIPSHPRV 453

Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            T T+  G   L I      D G YTC A+NA G
Sbjct: 454  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 2/83 (2%)

Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
           P+  TP ++ I    G    F      IG  T  + W  +   + +  R+T     G   
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGT 463

Query: 969 LTIKSVTVHDAGHYTCRAYNAIG 991
           L I+ V   D G YTC A NA G
Sbjct: 464 LIIRDVKESDQGAYTCEAMNARG 486



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            +I    G  + F C       PT  I W  N   +PS  R   T +    +L I    E 
Sbjct: 415  SIQASRGQTVTFTCVAIGV--PTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 472

Query: 2842 DSGIYTCKATNSKG 2855
            D G YTC+A N++G
Sbjct: 473  DQGAYTCEAMNARG 486



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 20/129 (15%)

Query: 3978 QIQSQTSLV-EMETTKFECQLAPVGDPNMKVEWFFNGK--PLLHKNRFTPIYDFGYVAMN 4034
            +I+S +S V E +T    C +A  G  + +V W+  G   P  H+ R + +Y F      
Sbjct: 2248 RIESSSSTVAEGQTLDLSCVVA--GQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ----- 2300

Query: 4035 FGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASW 4094
                 P D+G+Y+CRA+N  GM E    +  TG  G    + L     S + IR   +S 
Sbjct: 2301 ---ASPADAGQYVCRASN--GM-EASITVTVTGTQG----ANLAYPAGSTQPIRIEPSSS 2350

Query: 4095 QVTPEQVVE 4103
            QV   Q ++
Sbjct: 2351 QVAEGQTLD 2359



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 9/92 (9%)

Query: 3823 EPIVSTPPKFIT---QIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            EP  S P   +T   +I+S + + +EG   +           ++ W++ G  LP+ H+  
Sbjct: 2425 EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVH 2484

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                     L +L V   DSGEY+CR V   G
Sbjct: 2485 GS------RLRLLQVTPADSGEYVCRVVGSSG 2510



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 10/97 (10%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S S P+ ++  S+ P V EG+ + L C +     P   + W+  G S+   SR +T+   
Sbjct: 2627 SVSPPIRIE--SSSPTVVEGQTLDLNCVVARQ--PQAIITWYKRGGSLP--SRHQTHGSH 2680

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
                L +   + AD+GEY  RA N++ +   S ++ V
Sbjct: 2681 ----LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            ++P+ +    +  +++GQ A F + LI    A + +EW   N+ L+     +   +    
Sbjct: 3020 RSPVISIDPPSSTVQQGQDASF-KCLIHDGAAPISLEWKTRNQELEDNVHISPNGSI--- 3075

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             + I+   P + GTY C A NA G A +     VH   ++
Sbjct: 3076 -ITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTV 3114



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 11/124 (8%)

Query: 3826 VSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V +PP + T +  H +V+  E V+ +C       P L  +W R G  LP     R     
Sbjct: 3295 VESPP-YATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARNEL-- 3349

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
                L       EDSG Y CR  N  G     A +  +  P  +    +P G   +  +T
Sbjct: 3350 ----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3405

Query: 3945 -QME 3947
             Q+E
Sbjct: 3406 PQLE 3409



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDP--NLRIEFYHNGKALQSAARFHITFDFG 2298
            PP+ VT  R +     G+T  F C    V  P  N R+ + H    + S  R  +T + G
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGH----IPSHPRVTVTSEGG 460

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALG 2324
              +L I+     D G Y+ +A+NA G
Sbjct: 461  RGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 8/96 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APV ++    +  ++ G+ A F    T +  P L+    W G     G +          
Sbjct: 1865 APVVSIHPPQL-TVQPGQLAEFRCSATGSPTPTLE----WTGGP---GGQLPAKAQIHGG 1916

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            IL +    P D  +YLCRA+++ G+ V  A + V G
Sbjct: 1917 ILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHG 1952



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 9/85 (10%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            S+ P  I    SH V E E +   C V P +    ++ W++ G  LPS H+ R       
Sbjct: 2725 SSMPIRIESSSSH-VAEGETLDLNC-VVPGQ-AHAQVTWHKRGGSLPSHHQTRGS----- 2776

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
              L + +V   DSGEY+CR +   G
Sbjct: 2777 -RLRLHHVSPADSGEYVCRVMGSSG 2800



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 9/87 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            +  R   G  A F     G PTP +SW++           S+  + +  +  L++  + P
Sbjct: 3582 QEVRVPAGSAAVFPCIASGYPTPDISWSKLDG--------SLPPDSRLENNMLMLPSVRP 3633

Query: 139  GDEGEYTCTARNQYGEAICSVYIQ-PE 164
             D G Y CTA N+ G+     ++Q PE
Sbjct: 3634 QDAGTYVCTATNRQGKVKAFAHLQVPE 3660



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP+  T P + I  S   +  F C  I V   +  + W  N   + +  RV   ++ G  
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVAIGV--PTPIINWRLNWGHIPSHPRVTVTSEGGRG 462

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHG 3639
             L I  V + D G YTC+A N  G
Sbjct: 463  TLIIRDVKESDQGAYTCEAMNARG 486



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 9/95 (9%)

Query: 3822 EEPIVSTP-PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            E  ++  P P    +  S TV E + +   C V  +   +  + WY+ G  LP+ H+ R 
Sbjct: 2236 EASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQ--VTWYKRGGSLPARHQVRG 2293

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT 3915
                    L I      D+G+Y+CRA N      T
Sbjct: 2294 ------SRLYIFQASPADAGQYVCRASNGMEASIT 2322



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 244  YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
            YVG   VQ    +  +    +P  +   P  S + +G     + Q+SG+P     W +  
Sbjct: 1657 YVGNPSVQGGQCLPET--NQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSRED 1714

Query: 304  QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESPTESY 362
             R + S   +    H  + L   + Q SD+G Y     N +    +   L V E+P++  
Sbjct: 1715 GRPVPSGTQQ---RHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPI 1771

Query: 363  ---VQDQRSQYI 371
               V++QRSQ +
Sbjct: 1772 TVTVEEQRSQSV 1783



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S   V EGQ +   C +     ++ +V W K G  +   H+   +H      L ++ +  
Sbjct: 2444 SSSQVAEGQTLDLNCLV--AGQAHAQVTWHKRGGSLPARHQ---VHGS---RLRLLQVTP 2495

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRLT 1535
             DSG Y CR V   GT E S  +T
Sbjct: 2496 ADSGEYVCRVVGSSGTQEASVLVT 2519



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            D  DE   + P+ VT P+       GQ V F C    V      + W  N   +    R 
Sbjct: 396  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPI--INWRLNWGHIPSHPRV 453

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
                + G   L I D+   D G YTC A+N  G
Sbjct: 454  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 8/108 (7%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +PP  TT P    +    +   +C  +      +  +W   G  L    R    N+    
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQC--LAHGTPPLTFQWSRVGSSL--PGRATARNE---- 3348

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663
            +L        D+G Y C+ TN+ G A    +L V+G  G +    +P+
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPA 3396



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/70 (25%), Positives = 33/70 (47%), Gaps = 2/70 (2%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           ++G    F     G PTP+++W      +    + ++    + G  +L+I+ +   D+G 
Sbjct: 419 SRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTV--TSEGGRGTLIIRDVKESDQGA 476

Query: 144 YTCTARNQYG 153
           YTC A N  G
Sbjct: 477 YTCEAMNARG 486



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S + P  V+  S+ P V+EG+ + L C +   G    +V W+  G S+   ++       
Sbjct: 2046 SDASPPGVKIESSSPSVTEGQTLDLNCVVA--GSAHAQVTWYRRGGSLPPHTQVHGS--- 2100

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
                L +   + AD+GEY  R  N  G    S  V V+
Sbjct: 2101 ---RLRLPQVSPADSGEYVCRVENGSGPKEASITVSVL 2135



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+   +R +T+     
Sbjct: 2151 TRPIRIEPSSSH--VAEGQTLDLNCVVP--GQAHAQVTWHKRGGSLP--ARHQTHGSL-- 2202

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +   T AD+GEY    V   G    S +V +
Sbjct: 2203 --LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P +I    SH V E + +   C V P +    ++ WY+ G  LP+ H+           L
Sbjct: 2926 PIYIEASSSH-VTEGQTLDLNC-VVPGQ-AHAQVTWYKRGGSLPARHQTHGS------QL 2976

Query: 3890 DILYVYAEDSGEYICRAVNDFGED 3913
             +  V   DSGEY+CRA +  G +
Sbjct: 2977 RLHLVSPADSGEYVCRAASGPGPE 3000



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 25/55 (45%)

Query: 4090 MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            M A  Q T    V+ S     PV    P  +TV+ G+ A F C  TG P P + W
Sbjct: 1845 MFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1899



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+ V  R +T+     
Sbjct: 2340 TQPIRIEPSSSQ--VAEGQTLDLNCVVP--GQSHAQVTWHKRGGSLPV--RHQTHGSL-- 2391

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +  A+ AD+GEY  R +        S +V +
Sbjct: 2392 --LRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2424



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 8/96 (8%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P   +   S T +EG  +     +     P   I W K G S+ +  +        ++ L
Sbjct: 2630 PPIRIESSSPTVVEGQTLDLNCVV--ARQPQAIITWYKRGGSLPSRHQTHG----SHLRL 2683

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
              +S  + DSGEY CRA +     E   V+ V+P A
Sbjct: 2684 HQMS--VADSGEYVCRANNNIDALEASIVISVSPSA 2717



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 3695 PRFTVEIKDNID-VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P   + I+ ++  V  G  V F+C    +GDP  ++ W   G     G     +   G +
Sbjct: 3487 PSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVV 3540

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL--ESQLPQG 3802
               I ++   DAG+Y C ATN  G+  +   +   A   I +  E ++P G
Sbjct: 3541 R--IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAG 3589



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 10/123 (8%)

Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVAL 2169
            V +   TS++ +  G    FEC    + DP   + W   G  +R G         G V  
Sbjct: 3489 VLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVVR- 3541

Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL--DTQHPNGLEKIRQLEAQG 2227
             I +    D+G Y C ATN  G   +   L V     I +  + + P G   +    A G
Sbjct: 3542 -IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCIASG 3600

Query: 2228 HST 2230
            + T
Sbjct: 3601 YPT 3603



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 12/80 (15%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP--IHDFGYVALDIIDL 1509
            S++ V+ G  V FEC    + D   +V W K G     GH  RP  +   G V +  ++L
Sbjct: 3496 SVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GH-LRPGIVQSGGVVRIAHVEL 3547

Query: 1510 IAEDSGIYTCRAVNLVGTDE 1529
               D+G Y C A N  GT +
Sbjct: 3548 A--DAGQYRCTATNAAGTTQ 3565



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 9/100 (9%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++   P  +MP +++RV    AA F    I  G P   + W +    +   +RL      
Sbjct: 3571 LVQALPQISMP-QEVRVPAGSAAVFPC--IASGYPTPDISWSKLDGSLPPDSRLENN--- 3624

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                L +  V P+D+GTY C A N  G+    + L V  +
Sbjct: 3625 ---MLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3661


>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
            protein.
          Length = 1386

 Score = 97.5 bits (232), Expect = 1e-18
 Identities = 105/401 (26%), Positives = 158/401 (39%), Gaps = 52/401 (12%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKN-SPDFQIHTFSTKSILIIRQVFVE------DS 4478
            E A      +G P P I+WY+    +     D + H     S  +     V       D 
Sbjct: 79   EPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARPDE 138

Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD-TKV 4537
             V+  VA N  G A  S N  +E         ++   F  +  NV V  G+   L+    
Sbjct: 139  GVYTCVARNYLGAA-ASRNASLEV-------AVLRDDFRQSPGNVVVAVGEPAVLECVPP 190

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
             G     V W K+G +++ +   +I    G   L++      D+G Y CVA N AGE   
Sbjct: 191  RGHPEPSVSWRKDGARLKEE-EGRITIRGGK--LMMSHTLKSDAGMYVCVASNMAGERES 247

Query: 4598 DAECVVSL--PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
             A  V+ L  P+   +P  Q   A+AP                 + F C++ G P P ++
Sbjct: 248  AAAEVMVLERPSFLRRPVNQVVLADAP-----------------VTFLCEVKGDPPPRLR 290

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            W K D  +   +Y        +++L I     EDEG Y CVA NS GR   +  L V  P
Sbjct: 291  WRKEDGELPTGRY----EIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVP 346

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
             Q      +T  +D +   G+   F+ +      P I W +EG+ +   P   +   G  
Sbjct: 347  PQ-----LVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRF 401

Query: 4776 AV-----LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +V     L I      D G + C+A + AG +   A L +K
Sbjct: 402  SVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIK 442



 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 94/384 (24%), Positives = 160/384 (41%), Gaps = 44/384 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   +K   + +I     K  L++      D+ ++  VA N  G  + +
Sbjct: 192  GHPEPSVSWRKDGARLKEE-EGRITIRGGK--LMMSHTLKSDAGMYVCVASNMAGERESA 248

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            A  V+  +R         PSF     N  V +   V    +V G  P  + W K   ++ 
Sbjct: 249  AAEVMVLER---------PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL- 298

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P  R +I  +   ++L I     +D G Y CVA NS G A       V            
Sbjct: 299  PTGRYEIRSD---HSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV------------ 343

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYFQMS- 4672
                + PP+++   +D++ A G+++ F C+  G P P + W K     L+ PS+  Q + 
Sbjct: 344  ----HVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTG 399

Query: 4673 --RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT---PL 4727
                +    L I+     D G Y C A + AG +   A L++ +    D LP +    P 
Sbjct: 400  RFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEI-KGASLDGLPPVILQGPA 458

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
               +V  G       ++T   +P+++W ++G  + +  D Q     N   L I N  E D
Sbjct: 459  NQTLVL-GSSVWLPCRVTGNPQPSVRWKKDGQWL-QGDDLQFKTMANGT-LYIANVQEMD 515

Query: 4788 TGTFTCRATTAAGQVETSAKLVVK 4811
             G ++C A ++ G+   S  L ++
Sbjct: 516  MGFYSCVAKSSTGEATWSGWLKMR 539



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 90/351 (25%), Positives = 141/351 (40%), Gaps = 39/351 (11%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F ++     V       F  E  G+P P ++W +E+  +   P  +    S  S L I
Sbjct: 258  PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL---PTGRYEIRSDHS-LWI 313

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
              V  ED   +  VAEN  G A+ S +L V           VPP      Q+     G+ 
Sbjct: 314  GHVSAEDEGTYTCVAENSVGRAEASGSLSVH----------VPPQLVTQPQDQMAAPGES 363

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT------LLILEAYPQDSGKY 4584
            V    +  G  P  ++W K G +V     ++ L+  G ++      L I      D+G Y
Sbjct: 364  VAFQCETKGNPPPAIFWQKEGSQVLL-FPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYY 422

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C A++ AG     A   +   A+ D           PP I++   ++ +  G ++   C
Sbjct: 423  VCQAVSVAGSILAKALLEIK-GASLD---------GLPPVILQGPANQTLVLGSSVWLPC 472

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            ++ G P P+V+W K  + ++        +T    TL I+     D G Y CVA +S G  
Sbjct: 473  RVTGNPQPSVRWKKDGQWLQGDDL--QFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEA 530

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ-FKTQITSKIKPTIQW 4754
            T +  LK+ +       P   P        G P+Q   T+IT K   T+ W
Sbjct: 531  TWSGWLKMREDWGVSPDPPTEPSSP----PGAPSQPVVTEIT-KNSITLTW 576



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 60/192 (31%), Positives = 85/192 (44%), Gaps = 13/192 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI----RDDYNHKILVNESGN 447
           P+ V+   D  V+ G+     CR  GRP P + W+ N  ++     D   H++L+     
Sbjct: 64  PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123

Query: 448 HALMITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
               I +   +  D GV TCVARN  G  A +   N   +  V+   F +    + V  G
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASR---NASLEVAVLRDDFRQSPGNVVVAVG 180

Query: 506 EPVVLN-ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           EP VL      G P P ++W+KDG   +   E RI   GG   L +     SDA  Y C 
Sbjct: 181 EPAVLECVPPRGHPEPSVSWRKDGAR-LKEEEGRITIRGG--KLMMSHTLKSDAGMYVCV 237

Query: 565 AQNVAGSTATRA 576
           A N+AG   + A
Sbjct: 238 ASNMAGERESAA 249



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 56/192 (29%), Positives = 81/192 (42%), Gaps = 15/192 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F++   ++ V       F C V G P P + W   D ++     ++I      +H+L 
Sbjct: 258 PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTG-RYEI----RSDHSLW 312

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I +V+  D G  TCVA N  G       L+V      V P+ V +        GE V   
Sbjct: 313 IGHVSAEDEGTYTCVAENSVGRAEASGSLSVH-----VPPQLVTQPQDQMAAPGESVAFQ 367

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST-----LDIPRAKASDAAWYQCTAQ 566
               G P P I WQK+G  ++  P   +   G  S      L+I   +  DA +Y C A 
Sbjct: 368 CETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAV 427

Query: 567 NVAGSTATRARL 578
           +VAGS   +A L
Sbjct: 428 SVAGSILAKALL 439



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 18/201 (8%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI-----KPSKYFQMSRT 4674
            +A P I+E   D +V+ G+     C+  G+P P ++WYK    +      P  +  +  +
Sbjct: 61   DAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPS 120

Query: 4675 ADEYTLRI--SEAFPEDEGDYKCVAYNSAGRVTVA-AKLKV-TQPDQADNLPALTPLRDI 4730
               +  RI        DEG Y CVA N  G      A L+V    D     P      ++
Sbjct: 121  GALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPG-----NV 175

Query: 4731 VVYEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            VV  G+PA  +        +P++ W ++GA + E      I  G    L++ +T + D G
Sbjct: 176  VVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGK---LMMSHTLKSDAG 232

Query: 4790 TFTCRATTAAGQVETSAKLVV 4810
             + C A+  AG+ E++A  V+
Sbjct: 233  MYVCVASNMAGERESAAAEVM 253



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 89/391 (22%), Positives = 144/391 (36%), Gaps = 43/391 (10%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P VSW +  A L E      R   + G   L++      D G Y C A N  GE 
Sbjct: 191 RGHPEPSVSWRKDGARLKE---EEGRITIRGG--KLMMSHTLKSDAGMYVCVASNMAGE- 244

Query: 156 ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTE-QSRQTQKVAYTNGTD 214
                 +                 R V++ V   A  T  +  E +     ++ +     
Sbjct: 245 ------RESAAAEVMVLERPSFLRRPVNQVVLADAPVT--FLCEVKGDPPPRLRWRKEDG 296

Query: 215 HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
              T  +++ +     +  VS  +  T   V E+ V    E   SL    PP++  +P++
Sbjct: 297 ELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVG-RAEASGSLSVHVPPQLVTQPQD 355

Query: 275 SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
                G    FQ +  GNP P + W K G +++      +  T                G
Sbjct: 356 QMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPT----------------G 399

Query: 335 HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQF 394
            +++   +P G +      AV+     Y   Q          +   E    S   L P  
Sbjct: 400 RFSV---SPRGQL---NITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVI 453

Query: 395 VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR-DDYNHKILVNESGNHALMIT 453
           ++   ++ +  G      CRVTG P P V W  + + ++ DD   K + N +    L I 
Sbjct: 454 LQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGT----LYIA 509

Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
           NV   D G  +CVA++ +GE  +   L + E
Sbjct: 510 NVQEMDMGFYSCVAKSSTGEATWSGWLKMRE 540



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 54/199 (27%), Positives = 78/199 (39%), Gaps = 13/199 (6%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN-----FPIKNSPDF 4457
            G +    PP    + Q       E   F+ E  G P P I W +E      FP ++    
Sbjct: 339  GSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPT 398

Query: 4458 QIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT 4517
               + S +  L I  V   D+  +   A +  G+    A L ++     G    +PP   
Sbjct: 399  GRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDG----LPPVIL 454

Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEA 4576
                N  +  G  V L  +VTG     V W K+G+ +Q  D++ K +      TL I   
Sbjct: 455  QGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANG---TLYIANV 511

Query: 4577 YPQDSGKYECVAINSAGEA 4595
               D G Y CVA +S GEA
Sbjct: 512  QEMDMGFYSCVAKSSTGEA 530



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 46/184 (25%), Positives = 72/184 (39%), Gaps = 7/184 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL----VNESGN 447
           PQ V   QD+    G+   F C   G P P + W     Q+    +  +      + S  
Sbjct: 347 PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE-QVVAPKFVERFSTLNVREGE 506
             L IT V   D+G   C A + +G    +  L +       + P  ++  +   +  G 
Sbjct: 407 GQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGS 466

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            V L  R  G P P + W+KDG   +   +L+  T     TL I   +  D  +Y C A+
Sbjct: 467 SVWLPCRVTGNPQPSVRWKKDG-QWLQGDDLQFKTMAN-GTLYIANVQEMDMGFYSCVAK 524

Query: 567 NVAG 570
           +  G
Sbjct: 525 SSTG 528



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 6/110 (5%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E +V   P F+ +  +  V     V F C V  K DP  R+ W +    LP+G RY    
Sbjct: 251  EVMVLERPSFLRRPVNQVVLADAPVTFLCEV--KGDPPPRLRWRKEDGELPTG-RYEIRS 307

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            D    SL I +V AED G Y C A N  G      ++S    P ++ Q Q
Sbjct: 308  DH---SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQ 354



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 33/84 (39%), Positives = 43/84 (51%), Gaps = 7/84 (8%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            +N +V  +   + F C V+   DP  ++ W   +  LP+G RY+   D S   L I H  
Sbjct: 265  VNQVVLADAP-VTFLCEVKG--DPPPRLRWRKEDGELPTG-RYEIRSDHS---LWIGHVS 317

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
             ED G YTC A NS G A  SGSL
Sbjct: 318  AEDEGTYTCVAENSVGRAEASGSL 341



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 16/117 (13%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK---LLPSGHRYRT-- 3880
            V  PP+ +TQ +       E V F+C  E K +P   I W + G    L PS     T  
Sbjct: 343  VHVPPQLVTQPQDQMAAPGESVAFQC--ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGR 400

Query: 3881 --VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK-----KLPDIILQ 3930
              V   G   L+I  V   D+G Y+C+AV+  G    KA +  K      LP +ILQ
Sbjct: 401  FSVSPRG--QLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQ 455



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 6/97 (6%)

Query: 3712 PVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCR 3771
            PV F C V+  GDP  R+ W        TG R    +D    +L I ++ A D G YTC 
Sbjct: 274  PVTFLCEVK--GDPPPRLRWRKEDGELPTG-RYEIRSDH---SLWIGHVSAEDEGTYTCV 327

Query: 3772 ATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
            A N  G A  +  ++      +V + Q      GE +
Sbjct: 328  AENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESV 364



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 7/115 (6%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            EV V + P F+ +      L++     + C ++  P P +R  W      L +G RY   
Sbjct: 251  EVMVLERPSFLRRPVNQVVLADAPVT-FLCEVKGDPPPRLR--WRKEDGELPTG-RYEIR 306

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
            +D    +L I  V  ED G YTC A N++G+A +S  L+V     ++   Q + A
Sbjct: 307  SDH---SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMA 358



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 13/104 (12%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASSR 684
           V+ PPQ +   +   A  G  + F+   E  G+P   I W K G        QS++ + R
Sbjct: 343 VHVPPQLVTQPQDQMAAPGESVAFQC--ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGR 400

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           F S+   G   L++ ++   D+G Y C+AVS  G    KA+L +
Sbjct: 401 F-SVSPRG--QLNITAVQRGDAGYYVCQAVSVAGSILAKALLEI 441



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 6/139 (4%)

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRL 1334
            +++ T    A   + +  + A   +    ++ V++ P F R   N   +    V   C +
Sbjct: 222  MMSHTLKSDAGMYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEV 281

Query: 1335 QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEA 1394
            +  GD   R+ W      + TG   R     D+ +L +  V  ED G YTC A N +G A
Sbjct: 282  K--GDPPPRLRWRKEDGELPTG---RYEIRSDH-SLWIGHVSAEDEGTYTCVAENSVGRA 335

Query: 1395 VTSCALRVIAKKDLILESQ 1413
              S +L V     L+ + Q
Sbjct: 336  EASGSLSVHVPPQLVTQPQ 354



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 38/132 (28%), Positives = 55/132 (41%), Gaps = 13/132 (9%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D GTY+C A N  G+AE S  L     S    P+  T  Q+ +    G+S  F+C     
Sbjct: 320  DEGTYTCVAENSVGRAEASGSL-----SVHVPPQLVTQPQD-QMAAPGESVAFQCET--K 371

Query: 3177 DDPDMKIEWYHNGQP--MRHSTRIKTVSDFGFV---VLDIAYTQNHDSGEYVCRAYNKYG 3231
             +P   I W   G    +  S  ++    F       L+I   Q  D+G YVC+A +  G
Sbjct: 372  GNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAG 431

Query: 3232 EDFTRATINCYG 3243
                +A +   G
Sbjct: 432  SILAKALLEIKG 443



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/109 (30%), Positives = 47/109 (43%), Gaps = 6/109 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E+P F +   N  V    PV     +    DP  R+ W      +  G R++   D  
Sbjct: 254  VLERPSFLRRPVNQVVLADAPVTFLCEVK--GDPPPRLRWRKEDGELPTG-RYEIRSDH- 309

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082
              +L I +  AED GTY C A N+VG A  + S+ V     L     D+
Sbjct: 310  --SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQ 356



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 7/140 (5%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G PP     P++  L   SS    CR+      S+R  W  +G+  L G  ++       
Sbjct: 448  GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVR--WKKDGQ-WLQGDDLQ-FKTMAN 503

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
              L I  V + D G Y+C A +  GEAT S  L+++   G+  +P        G  S   
Sbjct: 504  GTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPV 563

Query: 3675 LEETLHKREEITIEDEKPNP 3694
            + E    +  IT+   KPNP
Sbjct: 564  VTEI--TKNSITL-TWKPNP 580



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 14/103 (13%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGK----VLQSGHRYRTSNDFGFAALDILTVYG 1911
            +S G+ A   CR E  P PN  +EWY NG     V +    +R     G A      V+G
Sbjct: 75   VSRGEPATLPCRAEGRPRPN--IEWYKNGARVATVREDPRAHRLLLPSG-ALFFPRIVHG 131

Query: 1912 E----DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                 D G YTC A N LG A S    N   + +++RD   +S
Sbjct: 132  RRARPDEGVYTCVARNYLGAAASR---NASLEVAVLRDDFRQS 171



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 11/123 (8%)

Query: 1698 QRHSAQDEV-ITQAPVFTM-PMKDIRVAENQAAHF-EARLIPVGDPKLRVEWLRNGVPIE 1754
            +R SA  EV + + P F   P+  + +A+       E +    GDP  R+ W +    + 
Sbjct: 244  ERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVK----GDPPPRLRWRKEDGELP 299

Query: 1755 ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814
             + R     D    +L + +V+ ED GTYTC A N +G A  S +L V     L  + Q 
Sbjct: 300  -TGRYEIRSDH---SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQD 355

Query: 1815 ESA 1817
            + A
Sbjct: 356  QMA 358



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 6/65 (9%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           +++G+P P + W RK+   +   +Y +R      D SL I  +   DEG YTC A N  G
Sbjct: 280 EVKGDPPPRLRW-RKEDGELPTGRYEIR-----SDHSLWIGHVSAEDEGTYTCVAENSVG 333

Query: 154 EAICS 158
            A  S
Sbjct: 334 RAEAS 338



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 14/41 (34%), Positives = 23/41 (56%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
           P+I ++P +  +  G  A    +  G PRP + W+KNG R+
Sbjct: 64  PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARV 104



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF-NGKQITSANRIQT 1094
            EV + ++P FL   +  N++V    A      E + D    + W   +G+  T    I++
Sbjct: 251  EVMVLERPSFLR--RPVNQVVLAD-APVTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRS 307

Query: 1095 YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
             H     +L I  V AED G YT VA N+ G A+ S S++V     + T
Sbjct: 308  DH-----SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVT 351



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   P + ++  ++   F C +    D   R+ W      L TG R +  +D     L
Sbjct: 258  PSFLRRPVNQVVLADAPVTFLCEV--KGDPPPRLRWRKEDGELPTG-RYEIRSDHS---L 311

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             IG V   D G YTC A N  G A  S  L V     ++ +PQ
Sbjct: 312  WIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQ 354



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 270 QKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
           Q P N  +  G  A  + V   G+P P V+W K+G RL    + E   T     L + +T
Sbjct: 170 QSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARL---KEEEGRITIRGGKLMMSHT 226

Query: 329 QKSDSGHYTLLAENPNG 345
            KSD+G Y  +A N  G
Sbjct: 227 LKSDAGMYVCVASNMAG 243



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 6/70 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            G+ A  +C + P G P   V W ++  +L E+  RIT         + +SH    D G+Y
Sbjct: 180  GEPAVLEC-VPPRGHPEPSVSWRKDGARLKEEEGRITIRGG----KLMMSHTLKSDAGMY 234

Query: 2450 MCRASNLLGE 2459
            +C ASN+ GE
Sbjct: 235  VCVASNMAGE 244



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 42/157 (26%), Positives = 60/157 (38%), Gaps = 15/157 (9%)

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            ER     E    +RP FL    +   L +     F C V+   DP   + W     ++  
Sbjct: 244  ERESAAAEVMVLERPSFLRRPVNQVVLADAP-VTFLCEVK--GDPPPRLRWRKEDGELPT 300

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
            G RY    D    +L I +  AED GTY C A N +G A  + +L V     ++   Q  
Sbjct: 301  G-RYEIRSDH---SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQD- 355

Query: 2215 NGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGT 2251
                   Q+ A G S   + E     PP    +  G+
Sbjct: 356  -------QMAAPGESVAFQCETKGNPPPAIFWQKEGS 385



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/42 (42%), Positives = 23/42 (54%)

Query: 1645 EDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALP 1686
            ED GTYTC A N++G A  SG   VH    +  + Q + A P
Sbjct: 319  EDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAP 360



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 9/108 (8%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK-NGQPVTIGHRFRPIHDFGY 1501
            +P F+ RP + + V+    V F C+++   D   ++ W K +G+  T  +  R  H    
Sbjct: 257  RPSFLRRPVN-QVVLADAPVTFLCEVKG--DPPPRLRWRKEDGELPTGRYEIRSDH---- 309

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE 1549
             +L I  + AED G YTC A N VG  E S  L+      +V   Q++
Sbjct: 310  -SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQ 356



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 36/106 (33%), Positives = 46/106 (43%), Gaps = 11/106 (10%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT---GSRVHTL---N 3748
            PR  VE   ++ V  G P    CR E  G P   I+W+ NG   AT     R H L   +
Sbjct: 64   PRI-VEQPPDLLVSRGEPATLPCRAE--GRPRPNIEWYKNGARVATVREDPRAHRLLLPS 120

Query: 3749 DFGFIALDIDYIYAR-DAGEYTCRATNKWGSATT-TAKITCSAKRD 3792
               F    +    AR D G YTC A N  G+A +  A +  +  RD
Sbjct: 121  GALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRD 166



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 4/83 (4%)

Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261
            E  GDP  R+ W      +  G R++   D    +L I H ++ D G YT  A N +G A
Sbjct: 280  EVKGDPPPRLRWRKEDGELPTG-RYEIRSDH---SLWIGHVSAEDEGTYTCVAENSVGRA 335

Query: 1262 HTSAIVRVIERSDIVTDTQNEQA 1284
              S  + V     +VT  Q++ A
Sbjct: 336  EASGSLSVHVPPQLVTQPQDQMA 358



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 4/75 (5%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   LE  V PR  P   + W K+G  L      + T   G + +S ++L++D +G+Y 
Sbjct: 180  GEPAVLEC-VPPRGHPEPSVSWRKDGARLKEEEG-RITIRGGKLMMS-HTLKSD-AGMYV 235

Query: 2717 CKATNLLGEAVSTAS 2731
            C A+N+ GE  S A+
Sbjct: 236  CVASNMAGERESAAA 250



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 6/65 (9%)

Query: 799 DPTMRVEWYK-DGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
           DP  R+ W K DG   T    I S       SL I H+ AED G+YT  A N +G A ++
Sbjct: 284 DPPPRLRWRKEDGELPTGRYEIRSDH-----SLWIGHVSAEDEGTYTCVAENSVGRAEAS 338

Query: 858 ASIRV 862
            S+ V
Sbjct: 339 GSLSV 343



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 4/68 (5%)

Query: 2667 EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            E + DP  ++ W K    L TG R +   D    +L I  +  +D G YTC A N +G A
Sbjct: 280  EVKGDPPPRLRWRKEDGELPTG-RYEIRSDH---SLWIGHVSAEDEGTYTCVAENSVGRA 335

Query: 2727 VSTASIKI 2734
             ++ S+ +
Sbjct: 336  EASGSLSV 343



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/126 (26%), Positives = 49/126 (38%), Gaps = 6/126 (4%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   +  D+G Y C+A +  G       LE    S    P         + L  G S 
Sbjct: 409  LNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSV 468

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMR-HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               C V    +P   + W  +GQ ++    + KT+++     L IA  Q  D G Y C A
Sbjct: 469  WLPCRVT--GNPQPSVRWKKDGQWLQGDDLQFKTMANG---TLYIANVQEMDMGFYSCVA 523

Query: 3227 YNKYGE 3232
             +  GE
Sbjct: 524  KSSTGE 529



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 15/38 (39%), Positives = 18/38 (47%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P  V  P  + V  GE A   CR  G P+P + W  NG
Sbjct: 64   PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNG 101



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 15/45 (33%), Positives = 26/45 (57%)

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
            +L I  V+  D G YTC A N++G+A  S +L++     ++ + Q
Sbjct: 310  SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQ 354



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/100 (25%), Positives = 38/100 (38%), Gaps = 7/100 (7%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP+  T P D + +   S  F+C      +    + W   G  +L            F +
Sbjct: 346  PPQLVTQPQDQMAAPGESVAFQCET--KGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSV 403

Query: 3617 -----LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
                 L I  V + DAG Y C+A +  G       L++KG
Sbjct: 404  SPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKG 443



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 41/161 (25%), Positives = 67/161 (41%), Gaps = 21/161 (13%)

Query: 3082 IEWFYNGKTIEA------SHRIRTVYAFGMVVLEILGTKTT-DSGTYSCRATNKWGQA-- 3132
            IEW+ NG  +        +HR+            + G +   D G Y+C A N  G A  
Sbjct: 95   IEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARPDEGVYTCVARNYLGAAAS 154

Query: 3133 -EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
               S+++  +     Q P       N+  +  G+ A  EC V P   P+  + W  +G  
Sbjct: 155  RNASLEVAVLRDDFRQSPG------NVV-VAVGEPAVLEC-VPPRGHPEPSVSWRKDGAR 206

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            ++      T+   G +++  ++T   D+G YVC A N  GE
Sbjct: 207  LKEEEGRITIRG-GKLMM--SHTLKSDAGMYVCVASNMAGE 244



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 8/101 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLL--HKNRFTPIYDFG 4029
            PP+ VTQ Q Q +    E+  F+C+    G+P   + W   G  +L        P   F 
Sbjct: 346  PPQLVTQPQDQMA-APGESVAFQCETK--GNPPPAIFWQKEGSQVLLFPSQSLQPTGRFS 402

Query: 4030 YVA---MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
                  +N   V   D+G Y+C+A ++ G    KA+++  G
Sbjct: 403  VSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKG 443



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+  Q   N     G +     ++ GNP P V W +K    ++ +    +      + +
Sbjct: 450 PPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRW-KKDGQWLQGDDLQFK---TMANGT 505

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L I  +   D G Y+C A++  GEA  S +++
Sbjct: 506 LYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 3/70 (4%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS-RYKLTYDGMYHFD 4168
            PPV +  P   T+  G      CRVTG+P+P V W  +G  +     ++K   +G  +  
Sbjct: 450  PPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLY-- 507

Query: 4169 IPKTRQYDTG 4178
            I   ++ D G
Sbjct: 508  IANVQEMDMG 517


>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
            2 (perlecan) protein.
          Length = 4391

 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 104/424 (24%), Positives = 174/424 (41%), Gaps = 48/424 (11%)

Query: 4394 AQTQERVV--EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI 4451
            AQ Q  V+   G + P  P +  ++ +   V     A       G P P I W +   P+
Sbjct: 3194 AQKQVEVIVDTGAMAPGAPQVQAEEAE-LTVEAGHTATLRCSATGSPAPTIHWSKLRSPL 3252

Query: 4452 KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGI 4511
                  +  T      LII +V  +DS  +   A +  G A+ +  L VE          
Sbjct: 3253 PWQHRLEGDT------LIIPRVAQQDSGQYICNATSPAGHAEATIILHVES--------- 3297

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
             PP  T   ++ +V +G+ V+L     GT P+   W + G  +  +   RN++L  +   
Sbjct: 3298 -PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFE--- 3353

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP- 4628
                  A P+DSG+Y C   N  G A   A+ +V  P     P     A + P   + P 
Sbjct: 3354 -----RAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP-PGSLPATSIPAGSTPTVQVTPQ 3407

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L+ K +  G ++EF C +       ++W+K    + P        +  +  LRI      
Sbjct: 3408 LETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP------GHSVQDGVLRIQNLDQS 3459

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             +G Y C A+   G+   +A+L V Q   +  +   T ++ +VV  G   +F+       
Sbjct: 3460 CQGTYICQAHGPWGKAQASAQL-VIQALPSVLINIRTSVQTVVV--GHAVEFECLALGDP 3516

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            KP + W + G  +   P   ++  G   V+ I +    D G + C AT AAG  ++   L
Sbjct: 3517 KPQVTWSKVGGHL--RPG--IVQSG--GVVRIAHVELADAGQYRCTATNAAGTTQSHVLL 3570

Query: 4809 VVKS 4812
            +V++
Sbjct: 3571 LVQA 3574



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 106/422 (25%), Positives = 164/422 (38%), Gaps = 57/422 (13%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQI 4459
            +  PV    PP  T  +QP ++     A F     G P P ++W     P    P   QI
Sbjct: 1863 LSAPVVSIHPPQLT--VQPGQL-----AEFRCSATGSPTPTLEW--TGGPGGQLPAKAQI 1913

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            H      IL +  V   D A +   A +  G     A L V      G GG   P   ++
Sbjct: 1914 HG----GILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVH-----GGGG---PRVQVS 1961

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             +   V +G+ VRL  +  G     + W K G  + P  R+   E     TLLI      
Sbjct: 1962 PERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARS---ERTDIATLLIPAITTA 2018

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y CVA + AG A+   + VV L A+   P P    +++P           V EGQ 
Sbjct: 2019 DAGFYLCVATSPAGTAQARIQVVV-LSASDASPPPVKIESSSPS----------VTEGQT 2067

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            ++ +C + G     V WY+    + P      SR      LR+ +  P D G+Y C   N
Sbjct: 2068 LDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSR------LRLPQVSPADSGEYVCRVEN 2121

Query: 4700 SAG----RVTVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKP 4750
             +G     +TV+             +P  T P+R       V EGQ       +  +   
Sbjct: 2122 GSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHA 2181

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             + W + G  +P        H+ + ++L +      D+G + C     +G +E S  + +
Sbjct: 2182 QVTWHKRGGSLPAR------HQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235

Query: 4811 KS 4812
            ++
Sbjct: 2236 EA 2237



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 100/412 (24%), Positives = 148/412 (35%), Gaps = 43/412 (10%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIH 4460
            EG     + P+ +       V + + A F+        P+ ++W   N  ++++    +H
Sbjct: 3013 EGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VH 3068

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                 SI+ I      +   +  VA N  G A+   NL V            PP+ ++  
Sbjct: 3069 ISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG----------PPTVSVLP 3118

Query: 4521 QN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            +  V V  G+ V L+    G       W +         +      D    L I  A P 
Sbjct: 3119 EGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPS 3178

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y C+A N+ G A+   E +V   A      PQ +A  A         +  V  G  
Sbjct: 3179 DAGTYVCLAQNALGTAQKQVEVIVDTGAMA-PGAPQVQAEEA---------ELTVEAGHT 3228

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
                C   G P PT+ W    KL  P  + Q     D  TL I     +D G Y C A +
Sbjct: 3229 ATLRCSATGSPAPTIHW---SKLRSPLPW-QHRLEGD--TLIIPRVAQQDSGQYICNATS 3282

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
             AG       L V  P  A  +P         V  G+  Q +         T QW R G+
Sbjct: 3283 PAGHAEATIILHVESPPYATTVP-----EHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 3337

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P            N +L       ED+G + CR T   G  E  A+L+V+
Sbjct: 3338 SLPGRA------TARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQ 3383



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 77/353 (21%), Positives = 148/353 (41%), Gaps = 32/353 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L + QV   DS  +        GT + S  + ++++        V     + + + ++
Sbjct: 2486 SRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASL 2545

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             +G  + L+  V    P  + W K G  +    R++I+       L I +  P DSG+Y 
Sbjct: 2546 ANGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGS----RLRIPQVTPADSGEYV 2599

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C   N AG    +   +V++  +     P      +PP  IE     +V EGQ ++ +C 
Sbjct: 2600 CHVSNGAGSR--ETSLIVTIQGSGSSHVPSV----SPPIRIESSSPTVV-EGQTLDLNCV 2652

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            +  +P   + WYK G  L  PS++    +T   + LR+ +    D G+Y C A N+   +
Sbjct: 2653 VARQPQAIITWYKRGGSL--PSRH----QTHGSH-LRLHQMSVADSGEYVCRANNNIDAL 2705

Query: 4705 TVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + V+    + + P  + P+R       V EG+       +  +    + W + G 
Sbjct: 2706 EASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG 2765

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +P        H+   + L + +    D+G + CR   ++G +E S  + +++
Sbjct: 2766 SLPSH------HQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEA 2812



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 90/356 (25%), Positives = 148/356 (41%), Gaps = 41/356 (11%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S+L + QV   DS  +        G  + S  + +E     G    +PP   + + +  V
Sbjct: 2201 SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGP---IPP-VRIESSSSTV 2256

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L   V G     V W K G  +    R+++        L I +A P D+G+Y 
Sbjct: 2257 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA--RHQVRGS----RLYIFQASPADAGQYV 2310

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N       +A   V++  T+        A +  P  IEP   + VAEGQ ++ +C 
Sbjct: 2311 CRASNGM-----EASITVTVTGTQGANLAYP-AGSTQPIRIEPSSSQ-VAEGQTLDLNCV 2363

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            + G+    V W+K G  L  P ++           LR+ +A P D G+Y C    S+  V
Sbjct: 2364 VPGQSHAQVTWHKRGGSL--PVRH-----QTHGSLLRLYQASPADSGEYVCRVLGSS--V 2414

Query: 4705 TVAAKLKVTQPDQADNLPAL--TPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWLRE 4757
             + A + VT  + A ++PAL  TP   I      V EGQ       +  +    + W + 
Sbjct: 2415 PLEASVLVTI-EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKR 2473

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            G  +P        H+ + + L +      D+G + CR   ++G  E S  + ++ +
Sbjct: 2474 GGSLPAR------HQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2523



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 100/413 (24%), Positives = 162/413 (39%), Gaps = 45/413 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            S PP+  +   P  V E +         G     + WYR    +   P  Q+H     S 
Sbjct: 2049 SPPPVKIESSSPS-VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLP--PHTQVHG----SR 2101

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT----LTAQNV 4523
            L + QV   DS  +    EN  G  + S  + V      G      P  T    +   + 
Sbjct: 2102 LRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSS 2161

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            +V  GQ + L+  V G     V W K G  +    R+   +  G+  L + +  P DSG+
Sbjct: 2162 HVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RH---QTHGSL-LRLHQVTPADSGE 2215

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C  + ++G    +A  +V++ A+   P P       PP  IE      VAEGQ ++ S
Sbjct: 2216 YVCHVVGTSGPL--EASVLVTIEASVI-PGP------IPPVRIES-SSSTVAEGQTLDLS 2265

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C + G+    V WYK    +      + SR      L I +A P D G Y C A N    
Sbjct: 2266 CVVAGQAHAQVTWYKRGGSLPARHQVRGSR------LYIFQASPADAGQYVCRASNGM-E 2318

Query: 4704 VTVAAKLKVTQ-PDQADNLPALTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
             ++   +  TQ  + A    +  P+R       V EGQ       +  +    + W + G
Sbjct: 2319 ASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG 2378

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              +P      + H+ + ++L +      D+G + CR   ++  +E S  + ++
Sbjct: 2379 GSLP------VRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE 2425



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 95/410 (23%), Positives = 160/410 (39%), Gaps = 52/410 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP  T   +   V   E  + +    G P    +W R    +           +   +L 
Sbjct: 3298 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPG------RATARNELLH 3351

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP----PSFTLTAQNVNV 4525
              +   EDS  +     N+ G+A+  A L+V+          +P    P+  +T Q    
Sbjct: 3352 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3411

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            + G  V     V   +   + W K G ++ P   + +  +DG   +  L+   Q  G Y 
Sbjct: 3412 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPG--HSV--QDGVLRIQNLDQSCQ--GTYI 3465

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI--VAEGQAIEFS 4643
            C A    G+A+  A+ V+                 A P ++  ++  +  V  G A+EF 
Sbjct: 3466 CQAHGPWGKAQASAQLVIQ----------------ALPSVLINIRTSVQTVVVGHAVEFE 3509

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C  +G P P V W K    ++P              +RI+     D G Y+C A N+AG 
Sbjct: 3510 CLALGDPKPQVTWSKVGGHLRP------GIVQSGGVVRIAHVELADAGQYRCTATNAAG- 3562

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             T +  L + Q      LP ++  +++ V  G  A F    +    P I W +    +P 
Sbjct: 3563 TTQSHVLLLVQA-----LPQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLP- 3616

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             PD ++     N +L++ +   +D GT+ C AT   G+V+  A L V  +
Sbjct: 3617 -PDSRL----ENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3661



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 74/305 (24%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V P+  + + +  V  GQ + L+  V G     V W K G  +    R+++    G+  L
Sbjct: 2435 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV---HGS-RL 2488

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             +L+  P DSG+Y C  + S+G    +A  +V++   + +         A P  IE    
Sbjct: 2489 RLLQVTPADSGEYVCRVVGSSGTQ--EASVLVTI---QQRLSGSHSQGVAYPVRIES-SS 2542

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
              +A G  ++ +C +  +   T+ WYK G  L  PS++  +        LRI +  P D 
Sbjct: 2543 ASLANGHTLDLNCLVASQAPHTITWYKRGGSL--PSRHQIVGS-----RLRIPQVTPADS 2595

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQIT 4745
            G+Y C   N AG    +  + + Q   + ++P+++P   I      V EGQ       + 
Sbjct: 2596 GEYVCHVSNGAGSRETSLIVTI-QGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 2654

Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             + +  I W + G  +P        H+ + + L +      D+G + CRA      +E S
Sbjct: 2655 RQPQAIITWYKRGGSLPSR------HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEAS 2708

Query: 4806 AKLVV 4810
              + V
Sbjct: 2709 IVISV 2713



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 79/354 (22%), Positives = 146/354 (41%), Gaps = 33/354 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L I QV   DS  +     N  G+ + S  + ++         + PP   + + +  V
Sbjct: 2583 SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPP-IRIESSSPTV 2641

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L+  V       + W K G  +    R+   +  G++ L + +    DSG+Y 
Sbjct: 2642 VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RH---QTHGSH-LRLHQMSVADSGEYV 2695

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N+      +A  V+S+  +   P   +   ++ P  IE      VAEG+ ++ +C 
Sbjct: 2696 CRANNNIDAL--EASIVISVSPSAGSP---SAPGSSMPIRIESSSSH-VAEGETLDLNCV 2749

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            + G+    V W+K    +      + SR      LR+    P D G+Y C    S+G + 
Sbjct: 2750 VPGQAHAQVTWHKRGGSLPSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLE 2803

Query: 4706 VAAKLKV-TQPDQADNLPA---LTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
             +  + +      A ++PA     P+R       V EGQ    K  +  +    + W + 
Sbjct: 2804 ASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKR 2863

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G  +P        H+ +  +L +      D+G ++C+ T ++G +E S  + ++
Sbjct: 2864 GGNLPAR------HQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIE 2911



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 87/362 (24%), Positives = 140/362 (38%), Gaps = 34/362 (9%)

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP---PSF 4516
            H  +  S L +  V   DS  +        G  + S  + +E           P   P  
Sbjct: 2770 HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPI 2829

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
             +   +  V  GQ + L   V G     V W K G  +    R+++    G   L + + 
Sbjct: 2830 RIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPA--RHQV---HGPL-LRLNQV 2883

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
             P DSG+Y C    S+G    +A  +V++  +   P P    A   P  IE      V E
Sbjct: 2884 SPADSGEYSCQVTGSSGTL--EASVLVTIEPSSPGPIPAPGLAQ--PIYIEASSSH-VTE 2938

Query: 4637 GQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            GQ ++ +C + G+    V WYK G  L  P+++           LR+    P D G+Y C
Sbjct: 2939 GQTLDLNCVVPGQAHAQVTWYKRGGSL--PARH-----QTHGSQLRLHLVSPADSGEYVC 2991

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQITSKIKP 4750
             A +  G    A+      P +  +    +P+  I      V +GQ A FK  I     P
Sbjct: 2992 RAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAP 3051

Query: 4751 -TIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +++W      + +      +H   N +++ I  T   + GT+ C A+ A G  ++   L
Sbjct: 3052 ISLEWKTRNQELEDN-----VHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNL 3106

Query: 4809 VV 4810
             V
Sbjct: 3107 SV 3108



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 30/292 (10%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V  GQ + L+  V G     V W K G  +   +R+   +  G+  L + +A P DSG+Y
Sbjct: 2352 VAEGQTLDLNCVVPGQSHAQVTWHKRGGSLP--VRH---QTHGSL-LRLYQASPADSGEY 2405

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C  + S+     +A  +V++     +P     A    P +        VAEGQ ++ +C
Sbjct: 2406 VCRVLGSS--VPLEASVLVTI-----EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNC 2458

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             + G+    V W+K    +        SR      LR+ +  P D G+Y C    S+G  
Sbjct: 2459 LVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSGEYVCRVVGSSGTQ 2512

Query: 4705 TVAAKLKVTQ-----PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + + Q       Q    P         +  G        + S+   TI W + G 
Sbjct: 2513 EASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGG 2572

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P        H+   + L I      D+G + C  +  AG  ETS  + ++
Sbjct: 2573 SLPSR------HQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2618



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 103/486 (21%), Positives = 168/486 (34%), Gaps = 54/486 (11%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A+F     G+PTP + WT      +           Q     L +  + P D+ +Y 
Sbjct: 1880 GQLAEFRCSATGSPTPTLEWTGGPGGQLPAKA-------QIHGGILRLPAVEPTDQAQYL 1932

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH--KAYGTQGYTTEQSRQ 203
            C A +  G+ +    +   G               H   TV    +A G    T    ++
Sbjct: 1933 CRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE 1992

Query: 204  TQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
               +     ++ +      +         +  F   +     G +  +I   +  S    
Sbjct: 1993 GGSLPPQARSERTDIATLLIPAIT---TADAGFYLCVATSPAGTAQARIQVVV-LSASDA 2048

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP +  +  +  + EG        ++G+   +VTW++ G  L     H   T  + + L
Sbjct: 2049 SPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSL---PPH---TQVHGSRL 2102

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            R+     +DSG Y    EN +G    S  ++V   T S          T         RI
Sbjct: 2103 RLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHS------GPSYTPVPGSTRPIRI 2156

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            E S                V EG+    +C V G+ + +VTW      +   +       
Sbjct: 2157 EPSSS-------------HVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARH------- 2196

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--STLN 501
            ++    L +  VT +DSG   C     SG       L  IE   +  P    R   S+  
Sbjct: 2197 QTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSST 2255

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + L+    G    ++TW K G  +    ++R       S L I +A  +DA  Y
Sbjct: 2256 VAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVR------GSRLYIFQASPADAGQY 2309

Query: 562  QCTAQN 567
             C A N
Sbjct: 2310 VCRASN 2315



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 56/177 (31%), Positives = 74/177 (41%), Gaps = 21/177 (11%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G    F+C   G P P+VTW      +R       +V   G   + I +V L+D+G 
Sbjct: 3500 VVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG-----IVQSGG--VVRIAHVELADAGQ 3552

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A N +G T     L V    Q+  P+ V       V  G   V    A G PTP I
Sbjct: 3553 YRCTATNAAGTTQSHVLLLVQALPQISMPQEV------RVPAGSAAVFPCIASGYPTPDI 3606

Query: 523  TWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +W K DG   +P P+ R+      + L +P  +  DA  Y CTA N  G     A L
Sbjct: 3607 SWSKLDG--SLP-PDSRLEN----NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHL 3656



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 45/177 (25%), Positives = 77/177 (43%), Gaps = 11/177 (6%)

Query: 395  VKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            V+V  +R  V  G+  R  CR  G P   +TW    R+       +     +    L+I 
Sbjct: 1958 VQVSPERTQVHAGRTVRLYCRAAGVPSATITW----RKEGGSLPPQARSERTDIATLLIP 2013

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
             +T +D+G   CVA + +G    + ++ V+       P      S+ +V EG+ + LN  
Sbjct: 2014 AITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCV 2073

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G+   ++TW + G  + P      HT    S L +P+   +D+  Y C  +N +G
Sbjct: 2074 VAGSAHAQVTWYRRGGSLPP------HTQVHGSRLRLPQVSPADSGEYVCRVENGSG 2124



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 112/531 (21%), Positives = 179/531 (33%), Gaps = 67/531 (12%)

Query: 52   VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
            +E+SG    +    PG   P   E    ++R A+G     +  + G     V+W ++   
Sbjct: 2810 IEASGS-SAVHVPAPGGAPPIRIEP--SSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGN 2866

Query: 112  LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXX 171
            L            Q     L + Q+ P D GEY+C      G    SV +  E       
Sbjct: 2867 LPA--------RHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPI 2918

Query: 172  XXXXXXXYRHVSETVEHKAYGTQ---GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEY 228
                     ++  +  H   G               Q   Y  G    +           
Sbjct: 2919 PAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRL 2978

Query: 229  RLLREVSFRESITKRYVG---ESDVQISTEIDRSLGP---VSPPKIAQKPRNSKLQEGAD 282
             L+      E + +   G   E +   +  +  S G    +  P I+  P +S +Q+G D
Sbjct: 2979 HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQD 3038

Query: 283  AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            A F+  +     P    +K   + +  N H    + N + + +  T+ S+ G Y      
Sbjct: 3039 ASFKCLIHDGAAPISLEWKTRNQELEDNVH---ISPNGSIITIVGTRPSNHGTYR----- 3090

Query: 343  PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
               C+ ++ Y   +S     V    +                +S     P +VKV     
Sbjct: 3091 ---CVASNAYGVAQSVVNLSVHGPPT----------------VSVLPEGPVWVKV----- 3126

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHA-LMITNVTLSDS 460
               GK    +C   G P     W  I+    + +     L++   +HA L I++   SD+
Sbjct: 3127 ---GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMD---SHAVLQISSAKPSDA 3180

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
            G   C+A+N  G    Q  + V        AP+     + L V  G    L   A G+P 
Sbjct: 3181 GTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPA 3240

Query: 520  PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P I W K   P+     L         TL IPR    D+  Y C A + AG
Sbjct: 3241 PTIHWSKLRSPLPWQHRLE------GDTLIIPRVAQQDSGQYICNATSPAG 3285



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 80/315 (25%), Positives = 109/315 (34%), Gaps = 41/315 (13%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP     P ++ +Q G   Q Q    G P     W + G  L          T  +  L
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGR------ATARNELL 3350

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG Y     N  G       L V+ P  S          T T Q       
Sbjct: 3351 HFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ------- 3403

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
                  + PQ     + + +  G    F C V      ++ WF    Q+     H +   
Sbjct: 3404 ------VTPQL----ETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP--GHSV--- 3446

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            + G   L I N+  S  G   C A    G+     +L VI+    V      R S   V 
Sbjct: 3447 QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQASAQL-VIQALPSVLINI--RTSVQTVV 3501

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             G  V     A+G P P++TW K G  + P     I   GG   + I   + +DA  Y+C
Sbjct: 3502 VGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGG--VVRIAHVELADAGQYRC 3555

Query: 564  TAQNVAGSTATRARL 578
            TA N AG+T +   L
Sbjct: 3556 TATNAAGTTQSHVLL 3570



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 115/528 (21%), Positives = 187/528 (35%), Gaps = 68/528 (12%)

Query: 62   TAGRPGEPSPPIFEQI-FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            +AG P  P   +  +I   ++  A+G        + G     V+W ++          S+
Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG--------SL 2767

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXX 178
              + QT    L +  + P D GEY C      G  EA   V I+  G             
Sbjct: 2768 PSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAP 2827

Query: 179  YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV-DTFEYRLLR--EVS 235
               +  +    A   +G T +        A+   T H    +          LLR  +VS
Sbjct: 2828 PIRIEPSSSRVA---EGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVS 2884

Query: 236  FRES--ITKRYVGES---DVQISTEIDRSL-GPVSPPKIAQ----KPRNSKLQEGADAQF 285
              +S   + +  G S   +  +   I+ S  GP+  P +AQ    +  +S + EG     
Sbjct: 2885 PADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2944

Query: 286  QVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               + G    +VTW+K G  L    +H+   TH  + LR+     +DSG Y   A +  G
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSL--PARHQ---THG-SQLRLHLVSPADSGEYVCRAASGPG 2998

Query: 346  CIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTE 405
                + +     P+E      RS  I+      T                       V +
Sbjct: 2999 PEQEASFTVTVPPSEGSSYRLRSPVISIDPPSST-----------------------VQQ 3035

Query: 406  GKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
            G+   F C +     P  + W   ++++ D+ +    ++ +G+  + I     S+ G   
Sbjct: 3036 GQDASFKCLIHDGAAPISLEWKTRNQELEDNVH----ISPNGS-IITIVGTRPSNHGTYR 3090

Query: 465  CVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
            CVA N  G       L+V     V V P+       + V+ G+ V L   + G P     
Sbjct: 3091 CVASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVWVKVGKAVTLECVSAGEPRSSAR 3145

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            W +         +         + L I  AK SDA  Y C AQN  G+
Sbjct: 3146 WTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGT 3193



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 5/133 (3%)

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            N  L I NV LSD+G   C   N          L+V     + AP        L V+ G+
Sbjct: 1822 NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQ 1881

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
                   A G+PTP + W       +P  + +IH  GG   L +P  + +D A Y C A 
Sbjct: 1882 LAEFRCSATGSPTPTLEWTGGPGGQLP-AKAQIH--GG--ILRLPAVEPTDQAQYLCRAH 1936

Query: 567  NVAGSTATRARLY 579
            + AG    RA L+
Sbjct: 1937 SSAGQQVARAVLH 1949



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 12/176 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G++  F C  TG P P + W             K  ++      L +  V  +D   
Sbjct: 1877 VQPGQLAEFRCSATGSPTPTLEWTGGPG---GQLPAKAQIHGG---ILRLPAVEPTDQAQ 1930

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A + +G+   +  L+V        P+         V  G  V L  RA G P+  I
Sbjct: 1931 YLCRAHSSAGQQVARAVLHV---HGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATI 1987

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            TW+K+G  + P       TD   +TL IP    +DA +Y C A + AG+   R ++
Sbjct: 1988 TWRKEGGSLPPQARSE-RTD--IATLLIPAITTADAGFYLCVATSPAGTAQARIQV 2040



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 53/231 (22%), Positives = 82/231 (35%), Gaps = 20/231 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H++          L +L     DSG
Sbjct: 2448 VAEGQTL--DLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSG 2499

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CR     G  E SV +    +  G   +   +   IE     L +G +    C V  
Sbjct: 2500 EYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVA- 2558

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
                   I WY  G  +   +R + V       L I      DSGEYVC   N  G   T
Sbjct: 2559 -SQAPHTITWYKRGGSL--PSRHQIVGSR----LRIPQVTPADSGEYVCHVSNGAGSRET 2611

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
               +   G G  ++ S+ P    +      ++G         + +P   IT
Sbjct: 2612 SLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIIT 2662



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 14/173 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + +GQ A ++  LI  G   + +EW    + +E +  I    +    ++ I+GT+ ++ G
Sbjct: 3033 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHG 3087

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
            TY C A+N +G A+  V L     S    P  +   +    +K G++   EC  V   +P
Sbjct: 3088 TYRCVASNAYGVAQSVVNL-----SVHGPPTVSVLPEGPVWVKVGKAVTLEC--VSAGEP 3140

Query: 3180 DMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                 W   +  P +   R   + D    VL I+  +  D+G YVC A N  G
Sbjct: 3141 RSSARWTRISSTPAKLEQRTYGLMD-SHAVLQISSAKPSDAGTYVCLAQNALG 3192



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 8/140 (5%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I   + +D+GTY C  +N +   + +  L          P  + H   +  ++ GQ 
Sbjct: 1824 ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT-VQPGQL 1882

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A F C+      P   +EW   G P     ++   +     +L +   +  D  +Y+CRA
Sbjct: 1883 AEFRCSAT--GSPTPTLEW--TGGP---GGQLPAKAQIHGGILRLPAVEPTDQAQYLCRA 1935

Query: 3227 YNKYGEDFTRATINCYGKGG 3246
            ++  G+   RA ++ +G GG
Sbjct: 1936 HSSAGQQVARAVLHVHGGGG 1955



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 80/320 (25%), Positives = 123/320 (38%), Gaps = 52/320 (16%)

Query: 261  GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
            G   P +I  +P +S++ EG        + G    +VTW K G  L    +H+   TH  
Sbjct: 2338 GSTQPIRI--EPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSL--PVRHQ---THG- 2389

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
            + LR+     +DSG Y       +  +  S  + +E P  S      +  +T T      
Sbjct: 2390 SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVP----ALGVTPTV----- 2439

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
             RIE S   +A             EG+    +C V G+ + +VTW      +     H++
Sbjct: 2440 -RIESSSSQVA-------------EGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV 2483

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGE------TAFQCRLNVIEKEQVVAPKFV 494
                 G+  L +  VT +DSG   C     SG          Q RL+    + V  P  +
Sbjct: 2484 ----HGSR-LRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRI 2538

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
            E  S+ ++  G  + LN          ITW K G  +    ++        S L IP+  
Sbjct: 2539 ES-SSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI------VGSRLRIPQVT 2591

Query: 555  ASDAAWYQCTAQNVAGSTAT 574
             +D+  Y C   N AGS  T
Sbjct: 2592 PADSGEYVCHVSNGAGSRET 2611



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 11/125 (8%)

Query: 4583 KYECVAINSAGEA--RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQA 4639
            ++ CV+ N    A   CD E         D P    +    PP+++ P ++ I A  GQ 
Sbjct: 372  QFRCVSTNMCIPASFHCDEE--------SDCPDRSDEFGCMPPQVVTPPRESIQASRGQT 423

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            + F+C  +G P P + W      I       ++      TL I +    D+G Y C A N
Sbjct: 424  VTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMN 483

Query: 4700 SAGRV 4704
            + G V
Sbjct: 484  ARGMV 488



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 24/72 (33%), Positives = 35/72 (48%)

Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           ++    G+ V     A+G PTP I W+ +   I  +P + + ++GG  TL I   K SD 
Sbjct: 415 SIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQ 474

Query: 559 AWYQCTAQNVAG 570
             Y C A N  G
Sbjct: 475 GAYTCEAMNARG 486



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 60/246 (24%), Positives = 95/246 (38%), Gaps = 42/246 (17%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E TI     +PP +   + ++  V  G  V   C     G P +   W   G       R
Sbjct: 3288 EATIILHVESPP-YATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLP--GR 3342

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
                N+     L  +     D+G Y CR TNK GSA   A++        +  + +P G 
Sbjct: 3343 ATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGS 3398

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            +                   P V   P    Q+++ ++  S  V F C V      +LR 
Sbjct: 3399 T-------------------PTVQVTP----QLETKSIGAS--VEFHCAVPSDRGTQLR- 3432

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             W++ G  LP GH   +V D G + +  L    +  G YIC+A   +G+    A +  + 
Sbjct: 3433 -WFKEGGQLPPGH---SVQD-GVLRIQNLDQSCQ--GTYICQAHGPWGKAQASAQLVIQA 3485

Query: 3924 LPDIIL 3929
            LP +++
Sbjct: 3486 LPSVLI 3491



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 2377 VFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSM 2436
            V T P ++I     GQT  F C  + +G PT  + W  N   I    R+T T + G  ++
Sbjct: 408  VVTPPRESIQ-ASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464

Query: 2437 TISHVRDEDEGVYMCRASNLLG 2458
             I  V++ D+G Y C A N  G
Sbjct: 465  IIRDVKESDQGAYTCEAMNARG 486



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/278 (20%), Positives = 105/278 (37%), Gaps = 24/278 (8%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A       G+P P + W++ ++PL   ++         GD +L+I ++   D G+Y 
Sbjct: 3226 GHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLE-------GD-TLIIPRVAQQDSGQYI 3277

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQ 205
            C A +  G A  ++ +  E                  +  ++  A+GT   T + SR   
Sbjct: 3278 CNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 3337

Query: 206  KVAYTNGTDHSSTDDFK----VDTFEY--RLLREVSFRESITKRYVGESDVQISTEIDRS 259
             +     T  +    F+     D+  Y  R+  +V   E+  +  V      +      S
Sbjct: 3338 SLP-GRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPA---TS 3393

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            +   S P +   P+      GA  +F   +  +   ++ WFK G +L     H +     
Sbjct: 3394 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQL--PPGHSV----Q 3447

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
               LR++N  +S  G Y   A  P G    S  L +++
Sbjct: 3448 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQA 3485



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 18/155 (11%)

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
            D+   + WF  G  +   H ++        VL I     +  GTY C+A   WG+A+ S 
Sbjct: 3426 DRGTQLRWFKEGGQLPPGHSVQDG------VLRIQNLDQSCQGTYICQAHGPWGKAQASA 3479

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +L  +           T +Q +     G +  FEC  + + DP  ++ W   G  +R   
Sbjct: 3480 QL-VIQALPSVLINIRTSVQTV---VVGHAVEFEC--LALGDPKPQVTWSKVGGHLRPG- 3532

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                V   G  V+ IA+ +  D+G+Y C A N  G
Sbjct: 3533 ---IVQSGG--VVRIAHVELADAGQYRCTATNAAG 3562



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 56/240 (23%), Positives = 91/240 (37%), Gaps = 44/240 (18%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            ++P +   +    +++ GE    +     T  P L  +W   G SL   +  R       
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARN------ 3347

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537
             +L      PEDSG Y CR  N  G A   A + VQG    +  + +P G   T+     
Sbjct: 3348 ELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ---- 3403

Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
                      +TP+ E+               S  +S  F C  +P +D   ++ WF  G
Sbjct: 3404 ----------VTPQLET--------------KSIGASVEFHC-AVP-SDRGTQLRWFKEG 3437

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
              L  G  V+        +L I  + Q   G Y C+A    G+A  S +L ++    +++
Sbjct: 3438 GQLPPGHSVQD------GVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLI 3491



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + S +  G     + W+  G ++ A H++R    +      I      D+G
Sbjct: 2256 VAEGQTL--DLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLY------IFQASPADAG 2307

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CRA+N   +A I+V +     +    P  +T    IE     + +GQ+    C VVP
Sbjct: 2308 QYVCRASNGM-EASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC-VVP 2365

Query: 3176 VDDPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                  ++ W+  G   P+RH T           +L +      DSGEYVCR
Sbjct: 2366 -GQSHAQVTWHKRGGSLPVRHQTHGS--------LLRLYQASPADSGEYVCR 2408



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 59/239 (24%), Positives = 87/239 (36%), Gaps = 19/239 (7%)

Query: 4581 SGKYECVAINSAGEARCDAEC---VVSLPATKD-KPKPQTKAANAPPEIIEPLKDKIVAE 4636
            +G Y C A       +   +C    V  P+ +  +  P+T  A    E+  P +  IV +
Sbjct: 1633 AGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEV-HPARS-IVPQ 1690

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G +    C++ G P     W + D    PS   Q  + ++   L      P D G Y C 
Sbjct: 1691 GGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSE---LHFPSVQPSDAGVYICT 1747

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP-TIQWL 4755
              N     T  A+L VT+         +   R   V  G    F     SK    T+ W 
Sbjct: 1748 CRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWT 1807

Query: 4756 R--EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            R   G L     DF       N +L I N    D GT+ C  +      + +A L V++
Sbjct: 1808 RLHNGKLPTRAMDF-------NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQA 1859



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 25/181 (13%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    +  ++P G     + W   G  + A H++         +L +      DSG
Sbjct: 2838 VAEGQTLDLKC-VVP-GQAHAQVTWHKRGGNLPARHQVHGP------LLRLNQVSPADSG 2889

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKP----RFTTHIQ-NIEGLKDGQSAHFECTVV 3174
             YSC+ T   G  E SV +     S G  P        +I+ +   + +GQ+    C VV
Sbjct: 2890 EYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VV 2948

Query: 3175 PVDDPDMKIEWYHNG--QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P      ++ WY  G   P RH T            L +      DSGEYVCRA +  G 
Sbjct: 2949 P-GQAHAQVTWYKRGGSLPARHQTHGSQ--------LRLHLVSPADSGEYVCRAASGPGP 2999

Query: 3233 D 3233
            +
Sbjct: 3000 E 3000



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 6/116 (5%)

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADN---LP--ALTPLRD-IVVYEGQPAQFKTQITS 4746
            ++CV+ N     +     +   PD++D    +P   +TP R+ I    GQ   F      
Sbjct: 373  FRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIG 432

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
               P I W      IP  P   +  EG    L+I +  E D G +TC A  A G V
Sbjct: 433  VPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMV 488



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 17/188 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W+  G ++ A H+           L +      DSG
Sbjct: 2936 VTEGQTL--DLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQ------LRLHLVSPADSG 2987

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE----GLKDGQSAHFECTVVP 3175
             Y CRA +  G  + +     V  S+G   R  + + +I+     ++ GQ A F+C +  
Sbjct: 2988 EYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHD 3047

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               P + +EW    Q +  +  I         ++ I  T+  + G Y C A N YG   +
Sbjct: 3048 GAAP-ISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHGTYRCVASNAYGVAQS 3102

Query: 3236 RATINCYG 3243
               ++ +G
Sbjct: 3103 VVNLSVHG 3110



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/306 (24%), Positives = 118/306 (38%), Gaps = 46/306 (15%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P +  +  +S++ EG        ++G    +VTW K G  L    +H++    + + LR+
Sbjct: 2437 PTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV----HGSRLRL 2490

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
                 +DSG Y         C V       E+     +Q + S   + +Q      RIE 
Sbjct: 2491 LQVTPADSGEYV--------CRVVGSSGTQEASVLVTIQQRLSG--SHSQGVAYPVRIES 2540

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            S  +LA              G     +C V  +    +TW+     +     H+I+ +  
Sbjct: 2541 SSASLA-------------NGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGSR- 2584

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQV--VAPKFVERFSTLN 501
                L I  VT +DSG   C   N +G  ET+    +       V  V+P      S+  
Sbjct: 2585 ----LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPT 2640

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + LN      P   ITW K G   +P+   R  T G  S L + +   +D+  Y
Sbjct: 2641 VVEGQTLDLNCVVARQPQAIITWYKRG-GSLPS---RHQTHG--SHLRLHQMSVADSGEY 2694

Query: 562  QCTAQN 567
             C A N
Sbjct: 2695 VCRANN 2700



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 55/212 (25%), Positives = 79/212 (37%), Gaps = 19/212 (8%)

Query: 368  SQYITDTQQRETEERIEISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
            +Q    T Q++ E  ++    A  APQ      +  V  G      C  TG P P + W 
Sbjct: 3187 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW- 3245

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
             +  +    + H++     G+  L+I  V   DSG   C A + +G       L+V  + 
Sbjct: 3246 -SKLRSPLPWQHRL----EGD-TLIIPRVAQQDSGQYICNATSPAGHAEATIILHV--ES 3297

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
               A    E  S   V+ GE V L   A GTP     W + G  +      R        
Sbjct: 3298 PPYATTVPEHAS---VQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR------NE 3348

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             L   RA   D+  Y+C   N  GS    A+L
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQL 3380



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 39/165 (23%), Positives = 61/165 (36%), Gaps = 12/165 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S  I W   G ++    R        +  L I    T D+G Y C AT+  G A+  
Sbjct: 1981 GVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCVATSPAGTAQAR 2037

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
            +++  +  S    P       +   + +GQ+    C V        ++ WY  G  +   
Sbjct: 2038 IQVVVLSASDASPPPVKIE-SSSPSVTEGQTLDLNCVV--AGSAHAQVTWYRRGGSLPPH 2094

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
            T++          L +      DSGEYVCR  N  G      T++
Sbjct: 2095 TQVHGSR------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2133



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 8/108 (7%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            + P + T +    S+   ET + +C LA  G P +  +W   G  L    R T   +   
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQC-LAH-GTPPLTFQWSRVGSSL--PGRATARNEL-- 3349

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP 4078
              ++F    PEDSG Y CR TN  G  E  A +   G PG +  + +P
Sbjct: 3350 --LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIP 3395



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 46/153 (30%), Positives = 61/153 (39%), Gaps = 23/153 (15%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+  G ++ + H+I      G   L I      DSG Y C  +N  G  E S+ +   
Sbjct: 2565 ITWYKRGGSLPSRHQI-----VGSR-LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2618

Query: 3142 DKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQ--PMRHS 3195
                   P  +  I+ IE     + +GQ+    C V     P   I WY  G   P RH 
Sbjct: 2619 GSGSSHVPSVSPPIR-IESSSPTVVEGQTLDLNCVVAR--QPQAIITWYKRGGSLPSRHQ 2675

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            T     S      + +A     DSGEYVCRA N
Sbjct: 2676 TH---GSHLRLHQMSVA-----DSGEYVCRANN 2700



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 29/218 (13%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            +I W+  G ++ + H+    +      L +      DSG Y CRA N     E S+ +  
Sbjct: 2660 IITWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVIS- 2712

Query: 3141 VDKSKG--QKPRFTTHIQ---NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG--QPMR 3193
            V  S G    P  +  I+   +   + +G++    C VVP      ++ W+  G   P  
Sbjct: 2713 VSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC-VVP-GQAHAQVTWHKRGGSLPSH 2770

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATINCYGKGGVYLES 3251
            H TR           L + +    DSGEYVCR     G  E     TI   G   V++ +
Sbjct: 2771 HQTRGSR--------LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPA 2822

Query: 3252 LQPDSLAKIR-ELESLQGAQQQTPSTPSAEPPKFITQI 3288
              P     IR E  S + A+ QT       P +   Q+
Sbjct: 2823 --PGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQV 2858



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQ 3165
            VL+I   K +D+GTY C A N  G A+  V++  VD             +  E  ++ G 
Sbjct: 3169 VLQISSAKPSDAGTYVCLAQNALGTAQKQVEV-IVDTGAMAPGAPQVQAEEAELTVEAGH 3227

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A   C+      P   I W     P+    R++   D     L I      DSG+Y+C 
Sbjct: 3228 TATLRCSA--TGSPAPTIHWSKLRSPLPWQHRLE--GD----TLIIPRVAQQDSGQYICN 3279

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
            A +  G     ATI  + +   Y  ++   +  +  E   LQ     TP
Sbjct: 3280 ATSPAGH--AEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTP 3326



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/52 (42%), Positives = 27/52 (51%)

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAF 2996
            I W  N   +    R  +TS+ G  TL + DV E D G YTC+A N RG  F
Sbjct: 438  INWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVF 489



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 52/218 (23%), Positives = 76/218 (34%), Gaps = 13/218 (5%)

Query: 385  ISEKALAPQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWFIND-RQIRDDYNHKILV 442
            + E   AP  V+V   R +  +G      C+V+G P     W   D R +      +   
Sbjct: 1669 LPETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQG 1728

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +E     L   +V  SD+GV  C  RN       +  L V E         VE   + +V
Sbjct: 1729 SE-----LHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSV 1783

Query: 503  REGEPVVLNARAVG-TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            R G  V     A   +P   + W +     + N +L          L I   + SDA  Y
Sbjct: 1784 RPGADVTFICTAKSKSPAYTLVWTR-----LHNGKLPTRAMDFNGILTIRNVQLSDAGTY 1838

Query: 562  QCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPT 599
             CT  N+       A L+             +H P+ T
Sbjct: 1839 VCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT 1876



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 56/276 (20%), Positives = 97/276 (35%), Gaps = 14/276 (5%)

Query: 85   QGGNAKFEGKLRGNPTPV-VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
            QG +A F+  +     P+ + W  +   L E N +        G + + I    P + G 
Sbjct: 3035 QGQDASFKCLIHDGAAPISLEWKTRNQEL-EDNVHI----SPNGSI-ITIVGTRPSNHGT 3088

Query: 144  YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR-HVSETVEHKAYGTQGYTTEQSR 202
            Y C A N YG A   V +   G              +   + T+E  + G    +   +R
Sbjct: 3089 YRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTR 3148

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262
             +   A      +   D   V         +      + +  +G +  Q+   +D     
Sbjct: 3149 ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMA 3208

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
               P++  +     ++ G  A  +   +G+P P + W K    L   ++ E        T
Sbjct: 3209 PGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLE------GDT 3262

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L +    + DSG Y   A +P G    +  L VESP
Sbjct: 3263 LIIPRVAQQDSGQYICNATSPAGHAEATIILHVESP 3298



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 12/117 (10%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            T+  + +  +AL PQ + + Q+  V  G    F C  +G P P+++W   D  +  D   
Sbjct: 3564 TQSHVLLLVQAL-PQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPD--- 3618

Query: 439  KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
                +   N+ LM+ +V   D+G   C A N+ G+      L V E+   V P F +
Sbjct: 3619 ----SRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER---VVPYFTQ 3668



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 1/84 (1%)

Query: 265 PPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           PP++   PR S +   G    F     G P P + W  N   + +  +  + +     TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464

Query: 324 RVRNTQKSDSGHYTLLAENPNGCI 347
            +R+ ++SD G YT  A N  G +
Sbjct: 465 IIRDVKESDQGAYTCEAMNARGMV 488



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 55/218 (25%), Positives = 79/218 (36%), Gaps = 27/218 (12%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H+          +L +      DSG
Sbjct: 2163 VAEGQTL--DLNCVVPGQAHAQVTWHKRGGSLPARHQTHGS------LLRLHQVTPADSG 2214

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDD 3178
             Y C      G  E SV L  ++ S    P     I++    + +GQ+    C V     
Sbjct: 2215 EYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA--GQ 2271

Query: 3179 PDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
               ++ WY  G   P RH  R           L I      D+G+YVCRA N      T 
Sbjct: 2272 AHAQVTWYKRGGSLPARHQVRGSR--------LYIFQASPADAGQYVCRASNGMEASITV 2323

Query: 3237 ATINCYGKGGVY-LESLQPDSLAKIRELESLQGAQQQT 3273
                  G    Y   S QP  +    E  S Q A+ QT
Sbjct: 2324 TVTGTQGANLAYPAGSTQPIRI----EPSSSQVAEGQT 2357



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 62/267 (23%), Positives = 97/267 (36%), Gaps = 46/267 (17%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            DSG Y C AT+  G AE ++ L        + P + T +     ++ G++   +C  +  
Sbjct: 3272 DSGQYICNATSPAGHAEATIILHV------ESPPYATTVPEHASVQAGETVQLQC--LAH 3323

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P +  +W   G  +      +        +L        DSG Y CR  NK G     
Sbjct: 3324 GTPPLTFQWSRVGSSLPGRATARNE------LLHFERAAPEDSGRYRCRVTNKVGSAEAF 3377

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +   G  G                  SL        STP+ +    +T  Q  TK + 
Sbjct: 3378 AQLLVQGPPG------------------SLPATSIPAGSTPTVQ----VTP-QLETKSI- 3413

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356
            G S  F    VP  D   ++ WF  G +LP GH  +        +L I    +   G Y 
Sbjct: 3414 GASVEFHC-AVP-SDRGTQLRWFKEGGQLPPGHSVQD------GVLRIQNLDQSCQGTYI 3465

Query: 3357 CVATNKLGRDSTKANLKCTSKENLILD 3383
            C A    G+    A L   +  +++++
Sbjct: 3466 CQAHGPWGKAQASAQLVIQALPSVLIN 3492



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 636 PPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPQ + P + S+ A  G  + F      +G PT  I W  N   I +  R T     G  
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG 462

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGV 719
           +L +  +   D G YTC A++A G+
Sbjct: 463 TLIIRDVKESDQGAYTCEAMNARGM 487



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
            V T P + I+ +  Q   F    + +G P   + W  N   I +  R+T   + G   L 
Sbjct: 408  VVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 465

Query: 1772 MKYVNPEDSGTYTCRAINELG 1792
            ++ V   D G YTC A+N  G
Sbjct: 466  IRDVKESDQGAYTCEAMNARG 486



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + S  P    +  S TV E + +   C V     P+  I WY+ G  LPS H+    +  
Sbjct: 2625 VPSVSPPIRIESSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH-- 2680

Query: 3885 GFVSLDILYVYAEDSGEYICRAVND 3909
                L +  +   DSGEY+CRA N+
Sbjct: 2681 ----LRLHQMSVADSGEYVCRANNN 2701



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 55/239 (23%), Positives = 89/239 (37%), Gaps = 44/239 (18%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            +S   + EG      C V     P   I W+  G  + + H+   +H      L +    
Sbjct: 2636 SSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH------LRLHQMS 2687

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE 2235
              DSG Y+C+A N +           A   +I++      G        A G S  I +E
Sbjct: 2688 VADSGEYVCRANNNID----------ALEASIVISVSPSAGSPS-----APGSSMPIRIE 2732

Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295
                           ++HV EG+T    C V      + ++ ++  G +L S    H T 
Sbjct: 2733 S-------------SSSHVAEGETLDLNCVVPG--QAHAQVTWHKRGGSLPS---HHQTR 2774

Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  L + H  P D+GEY  + + + G   +++ +T+ A GS       P G   IR
Sbjct: 2775 GS---RLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIR 2830



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 390 LAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           + PQ V   ++    + G+   F C   G P P + W +N   I   +    + +E G  
Sbjct: 404 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHI-PSHPRVTVTSEGGRG 462

Query: 449 ALMITNVTLSDSGVVTCVARNKSG 472
            L+I +V  SD G  TC A N  G
Sbjct: 463 TLIIRDVKESDQGAYTCEAMNARG 486



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 62/244 (25%), Positives = 91/244 (37%), Gaps = 46/244 (18%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            + +     +PP   +E   +  V EG  +  +C V   G    ++ W+  G      ++V
Sbjct: 2041 VVLSASDASPPPVKIE-SSSPSVTEGQTLDLNCVV--AGSAHAQVTWYRRGGSLPPHTQV 2097

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
            H         L +  +   D+GEY CR  N  GS    A IT S     VL         
Sbjct: 2098 HGSR------LRLPQVSPADSGEYVCRVEN--GSGPKEASITVS-----VLHG------- 2137

Query: 3805 GEKIKELERGRISDAPKEEPIV-STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
                           P   P+  ST P  I    SH V E + +   C V P +    ++
Sbjct: 2138 -----------THSGPSYTPVPGSTRPIRIEPSSSH-VAEGQTLDLNC-VVPGQ-AHAQV 2183

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKATISC 3921
             W++ G  LP+ H+       G + L +  V   DSGEY+C  V   G  E     TI  
Sbjct: 2184 TWHKRGGSLPARHQTH-----GSL-LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEA 2237

Query: 3922 KKLP 3925
              +P
Sbjct: 2238 SVIP 2241



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 2495 ERRSEEPDREFEKPIFT-QVLTGPSELWEGQHAHYEA-RVVPVGDPSLRFEWYINGVELK 2552
            +  S+ PDR  E      QV+T P E  +           V +G P+    W +N   + 
Sbjct: 389  DEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIP 448

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
               R   T + G  TL I  V  +D G Y C+A+N  G
Sbjct: 449  SHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 1/90 (1%)

Query: 4505 RQGRGGIVPPSF-TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
            R    G +PP   T   +++  + GQ V       G     + W  N   +    R  + 
Sbjct: 397  RSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVT 456

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
             E G  TL+I +    D G Y C A+N+ G
Sbjct: 457  SEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR-NGVPIEASNRLTTMHDFGYVAL 1770
            V  +P   + V   +A   E   +  G+P+    W R +  P +   R   + D  +  L
Sbjct: 3114 VSVLPEGPVWVKVGKAVTLEC--VSAGEPRSSARWTRISSTPAKLEQRTYGLMD-SHAVL 3170

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +    P D+GTY C A N LG A     + V + A
Sbjct: 3171 QISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGA 3206



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 5/99 (5%)

Query: 3035 EPGQQPD--DDTG-RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI 3091
            E    PD  D+ G  PP+  T  ++ +  S GQ   +  + +  G  + +I W  N   I
Sbjct: 390  EESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTF--TCVAIGVPTPIINWRLNWGHI 447

Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
             +  R+      G   L I   K +D G Y+C A N  G
Sbjct: 448  PSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q+GQ A F C LI  G   + +EW    + +ED+  I+         +TI   R  + G
Sbjct: 3033 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGSI----ITIVGTRPSNHG 3087

Query: 2448 VYMCRASNLLG 2458
             Y C ASN  G
Sbjct: 3088 TYRCVASNAYG 3098



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     +++I    G  V F C    +G PT  I+W  N     +  RV   ++ G  
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVA--IGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG 462

Query: 3754 ALDIDYIYARDAGEYTCRATNKWG 3777
             L I  +   D G YTC A N  G
Sbjct: 463  TLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 38/178 (21%)

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            L + H      L +  V P DSG Y C   N  G   TS  + +Q        S H  ++
Sbjct: 2574 LPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG-----SSHVPSV 2628

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
                ++E SS                        PT + EGQ+    C +     P   +
Sbjct: 2629 SPPIRIESSS------------------------PTVV-EGQTLDLNCVVAR--QPQAII 2661

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             WY  G  L S H+   S+      L +  +   DSGEY C+A NN+    +SI ++V
Sbjct: 2662 TWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+ +T      + S GQ+  + C     P P   + W  N   + S  R   +++ G   
Sbjct: 406  PQVVTPPRESIQASRGQTVTFTCVAIGVPTPI--INWRLNWGHIPSHPRVTVTSEGGRGT 463

Query: 1904 LDILTVYGEDSGEYTCKAINNLG 1926
            L I  V   D G YTC+A+N  G
Sbjct: 464  LIIRDVKESDQGAYTCEAMNARG 486



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 12/122 (9%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI--RAGHRYRTTHDF 2164
            + P + T +    +++ G+    +C       P LT  W   G  +  RA  R    H F
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLPGRATARNELLH-F 3352

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
               A        EDSG Y C+ TNK+G A     L V G    +  T  P G     Q+ 
Sbjct: 3353 ERAA-------PEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3405

Query: 2225 AQ 2226
             Q
Sbjct: 3406 PQ 3407



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 6/66 (9%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P L  +W R G  +    R T  ++     L+ +   PEDSG Y CR  N++G A   
Sbjct: 3324 GTPPLTFQWSRVGSSLPG--RATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAF 3377

Query: 1798 STLFVQ 1803
            + L VQ
Sbjct: 3378 AQLLVQ 3383



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 10/111 (9%)

Query: 3825 IVSTPPKFITQIKS--HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            ++   P  +  I++   TV     V FEC      DPK ++ W + G     GH    + 
Sbjct: 3482 VIQALPSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GHLRPGIV 3534

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
              G V + I +V   D+G+Y C A N  G   +   +  + LP I +  +V
Sbjct: 3535 QSGGV-VRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEV 3584



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 10/110 (9%)

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +EP   +  +  +  V ++  S+   V+EG+ + L C +   G    +V W   G S+  
Sbjct: 2424 IEPAGSVPALGVTPTVRIE--SSSSQVAEGQTLDLNCLVA--GQAHAQVTWHKRGGSLP- 2478

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             +R + +       L ++  T AD+GEY  R V   G+   S +V + +R
Sbjct: 2479 -ARHQVHGS----RLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2523



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 53/231 (22%), Positives = 77/231 (33%), Gaps = 45/231 (19%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P   +     +VAE Q    +   +  G    +V W + G        L   H      L
Sbjct: 2437 PTVRIESSSSQVAEGQT--LDLNCLVAGQAHAQVTWHKRG------GSLPARHQVHGSRL 2488

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +  V P DSG Y CR +   G    S  + +Q +    L   H   +    ++E SS  
Sbjct: 2489 RLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR----LSGSHSQGVAYPVRIESSS-- 2542

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
                                     L+ G +    C +     P+  + WY  G  L S 
Sbjct: 2543 -----------------------ASLANGHTLDLNCLVASQA-PH-TITWYKRGGSLPSR 2577

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            H+   S       L I  V   DSGEY C   N  G   +S+ + +Q   S
Sbjct: 2578 HQIVGSR------LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2622



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 1568 DMVDEVTTQAP-ICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF 1626
            D  DE     P + T   ++++   GQ   F    + +   T  + W  N   + S  R 
Sbjct: 396  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFT--CVAIGVPTPIINWRLNWGHIPSHPRV 453

Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            T T+  G   L I      D G YTC A+NA G
Sbjct: 454  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 2/83 (2%)

Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
           P+  TP ++ I    G    F      IG  T  + W  +   + +  R+T     G   
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGT 463

Query: 969 LTIKSVTVHDAGHYTCRAYNAIG 991
           L I+ V   D G YTC A NA G
Sbjct: 464 LIIRDVKESDQGAYTCEAMNARG 486



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            +I    G  + F C       PT  I W  N   +PS  R   T +    +L I    E 
Sbjct: 415  SIQASRGQTVTFTCVAIGV--PTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 472

Query: 2842 DSGIYTCKATNSKG 2855
            D G YTC+A N++G
Sbjct: 473  DQGAYTCEAMNARG 486



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 20/129 (15%)

Query: 3978 QIQSQTSLV-EMETTKFECQLAPVGDPNMKVEWFFNGK--PLLHKNRFTPIYDFGYVAMN 4034
            +I+S +S V E +T    C +A  G  + +V W+  G   P  H+ R + +Y F      
Sbjct: 2248 RIESSSSTVAEGQTLDLSCVVA--GQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ----- 2300

Query: 4035 FGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASW 4094
                 P D+G+Y+CRA+N  GM E    +  TG  G    + L     S + IR   +S 
Sbjct: 2301 ---ASPADAGQYVCRASN--GM-EASITVTVTGTQG----ANLAYPAGSTQPIRIEPSSS 2350

Query: 4095 QVTPEQVVE 4103
            QV   Q ++
Sbjct: 2351 QVAEGQTLD 2359



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 9/92 (9%)

Query: 3823 EPIVSTPPKFIT---QIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            EP  S P   +T   +I+S + + +EG   +           ++ W++ G  LP+ H+  
Sbjct: 2425 EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVH 2484

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                     L +L V   DSGEY+CR V   G
Sbjct: 2485 GS------RLRLLQVTPADSGEYVCRVVGSSG 2510



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 10/97 (10%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S S P+ ++  S+ P V EG+ + L C +     P   + W+  G S+   SR +T+   
Sbjct: 2627 SVSPPIRIE--SSSPTVVEGQTLDLNCVVARQ--PQAIITWYKRGGSLP--SRHQTHGSH 2680

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
                L +   + AD+GEY  RA N++ +   S ++ V
Sbjct: 2681 ----LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            ++P+ +    +  +++GQ A F + LI    A + +EW   N+ L+     +   +    
Sbjct: 3020 RSPVISIDPPSSTVQQGQDASF-KCLIHDGAAPISLEWKTRNQELEDNVHISPNGSI--- 3075

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             + I+   P + GTY C A NA G A +     VH   ++
Sbjct: 3076 -ITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTV 3114



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 11/124 (8%)

Query: 3826 VSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V +PP + T +  H +V+  E V+ +C       P L  +W R G  LP     R     
Sbjct: 3295 VESPP-YATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARNEL-- 3349

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
                L       EDSG Y CR  N  G     A +  +  P  +    +P G   +  +T
Sbjct: 3350 ----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3405

Query: 3945 -QME 3947
             Q+E
Sbjct: 3406 PQLE 3409



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDP--NLRIEFYHNGKALQSAARFHITFDFG 2298
            PP+ VT  R +     G+T  F C    V  P  N R+ + H    + S  R  +T + G
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGH----IPSHPRVTVTSEGG 460

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALG 2324
              +L I+     D G Y+ +A+NA G
Sbjct: 461  RGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 8/96 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APV ++    +  ++ G+ A F    T +  P L+    W G     G +          
Sbjct: 1865 APVVSIHPPQL-TVQPGQLAEFRCSATGSPTPTLE----WTGGP---GGQLPAKAQIHGG 1916

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            IL +    P D  +YLCRA+++ G+ V  A + V G
Sbjct: 1917 ILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHG 1952



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 9/85 (10%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            S+ P  I    SH V E E +   C V P +    ++ W++ G  LPS H+ R       
Sbjct: 2725 SSMPIRIESSSSH-VAEGETLDLNC-VVPGQ-AHAQVTWHKRGGSLPSHHQTRGS----- 2776

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
              L + +V   DSGEY+CR +   G
Sbjct: 2777 -RLRLHHVSPADSGEYVCRVMGSSG 2800



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 9/87 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            +  R   G  A F     G PTP +SW++           S+  + +  +  L++  + P
Sbjct: 3582 QEVRVPAGSAAVFPCIASGYPTPDISWSKLDG--------SLPPDSRLENNMLMLPSVRP 3633

Query: 139  GDEGEYTCTARNQYGEAICSVYIQ-PE 164
             D G Y CTA N+ G+     ++Q PE
Sbjct: 3634 QDAGTYVCTATNRQGKVKAFAHLQVPE 3660



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP+  T P + I  S   +  F C  I V   +  + W  N   + +  RV   ++ G  
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVAIGV--PTPIINWRLNWGHIPSHPRVTVTSEGGRG 462

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHG 3639
             L I  V + D G YTC+A N  G
Sbjct: 463  TLIIRDVKESDQGAYTCEAMNARG 486



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 9/95 (9%)

Query: 3822 EEPIVSTP-PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            E  ++  P P    +  S TV E + +   C V  +   +  + WY+ G  LP+ H+ R 
Sbjct: 2236 EASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQ--VTWYKRGGSLPARHQVRG 2293

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT 3915
                    L I      D+G+Y+CRA N      T
Sbjct: 2294 ------SRLYIFQASPADAGQYVCRASNGMEASIT 2322



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 244  YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
            YVG   VQ    +  +    +P  +   P  S + +G     + Q+SG+P     W +  
Sbjct: 1657 YVGNPSVQGGQCLPET--NQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSRED 1714

Query: 304  QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESPTESY 362
             R + S   +    H  + L   + Q SD+G Y     N +    +   L V E+P++  
Sbjct: 1715 GRPVPSGTQQ---RHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPI 1771

Query: 363  ---VQDQRSQYI 371
               V++QRSQ +
Sbjct: 1772 TVTVEEQRSQSV 1783



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S   V EGQ +   C +     ++ +V W K G  +   H+   +H      L ++ +  
Sbjct: 2444 SSSQVAEGQTLDLNCLV--AGQAHAQVTWHKRGGSLPARHQ---VHGS---RLRLLQVTP 2495

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRLT 1535
             DSG Y CR V   GT E S  +T
Sbjct: 2496 ADSGEYVCRVVGSSGTQEASVLVT 2519



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            D  DE   + P+ VT P+       GQ V F C    V      + W  N   +    R 
Sbjct: 396  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPI--INWRLNWGHIPSHPRV 453

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
                + G   L I D+   D G YTC A+N  G
Sbjct: 454  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 8/108 (7%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +PP  TT P    +    +   +C  +      +  +W   G  L    R    N+    
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQC--LAHGTPPLTFQWSRVGSSL--PGRATARNE---- 3348

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663
            +L        D+G Y C+ TN+ G A    +L V+G  G +    +P+
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPA 3396



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/70 (25%), Positives = 33/70 (47%), Gaps = 2/70 (2%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           ++G    F     G PTP+++W      +    + ++    + G  +L+I+ +   D+G 
Sbjct: 419 SRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTV--TSEGGRGTLIIRDVKESDQGA 476

Query: 144 YTCTARNQYG 153
           YTC A N  G
Sbjct: 477 YTCEAMNARG 486



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+   +R +T+     
Sbjct: 2151 TRPIRIEPSSSH--VAEGQTLDLNCVVP--GQAHAQVTWHKRGGSLP--ARHQTHGSL-- 2202

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +   T AD+GEY    V   G    S +V +
Sbjct: 2203 --LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P +I    SH V E + +   C V P +    ++ WY+ G  LP+ H+           L
Sbjct: 2926 PIYIEASSSH-VTEGQTLDLNC-VVPGQ-AHAQVTWYKRGGSLPARHQTHGS------QL 2976

Query: 3890 DILYVYAEDSGEYICRAVNDFGED 3913
             +  V   DSGEY+CRA +  G +
Sbjct: 2977 RLHLVSPADSGEYVCRAASGPGPE 3000



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 25/55 (45%)

Query: 4090 MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            M A  Q T    V+ S     PV    P  +TV+ G+ A F C  TG P P + W
Sbjct: 1845 MFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1899



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S + P  V+  S+ P V+EG+ + L C +   G    +V W+  G S+   ++       
Sbjct: 2046 SDASPPPVKIESSSPSVTEGQTLDLNCVVA--GSAHAQVTWYRRGGSLPPHTQVHGS--- 2100

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
                L +   + AD+GEY  R  N  G    S  V V+
Sbjct: 2101 ---RLRLPQVSPADSGEYVCRVENGSGPKEASITVSVL 2135



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+ V  R +T+     
Sbjct: 2340 TQPIRIEPSSSQ--VAEGQTLDLNCVVP--GQSHAQVTWHKRGGSLPV--RHQTHGSL-- 2391

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +  A+ AD+GEY  R +        S +V +
Sbjct: 2392 --LRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2424



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 8/96 (8%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P   +   S T +EG  +     +     P   I W K G S+ +  +        ++ L
Sbjct: 2630 PPIRIESSSPTVVEGQTLDLNCVV--ARQPQAIITWYKRGGSLPSRHQTHG----SHLRL 2683

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
              +S  + DSGEY CRA +     E   V+ V+P A
Sbjct: 2684 HQMS--VADSGEYVCRANNNIDALEASIVISVSPSA 2717



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 3695 PRFTVEIKDNID-VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P   + I+ ++  V  G  V F+C    +GDP  ++ W   G     G     +   G +
Sbjct: 3487 PSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVV 3540

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL--ESQLPQG 3802
               I ++   DAG+Y C ATN  G+  +   +   A   I +  E ++P G
Sbjct: 3541 R--IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAG 3589



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 10/123 (8%)

Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVAL 2169
            V +   TS++ +  G    FEC    + DP   + W   G  +R G         G V  
Sbjct: 3489 VLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVVR- 3541

Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL--DTQHPNGLEKIRQLEAQG 2227
             I +    D+G Y C ATN  G   +   L V     I +  + + P G   +    A G
Sbjct: 3542 -IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCIASG 3600

Query: 2228 HST 2230
            + T
Sbjct: 3601 YPT 3603



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 12/80 (15%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP--IHDFGYVALDIIDL 1509
            S++ V+ G  V FEC    + D   +V W K G     GH  RP  +   G V +  ++L
Sbjct: 3496 SVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GH-LRPGIVQSGGVVRIAHVEL 3547

Query: 1510 IAEDSGIYTCRAVNLVGTDE 1529
               D+G Y C A N  GT +
Sbjct: 3548 A--DAGQYRCTATNAAGTTQ 3565



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 9/100 (9%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++   P  +MP +++RV    AA F    I  G P   + W +    +   +RL      
Sbjct: 3571 LVQALPQISMP-QEVRVPAGSAAVFPC--IASGYPTPDISWSKLDGSLPPDSRLENN--- 3624

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                L +  V P+D+GTY C A N  G+    + L V  +
Sbjct: 3625 ---MLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3661


>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
            2 (perlecan) protein.
          Length = 4391

 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 104/424 (24%), Positives = 174/424 (41%), Gaps = 48/424 (11%)

Query: 4394 AQTQERVV--EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI 4451
            AQ Q  V+   G + P  P +  ++ +   V     A       G P P I W +   P+
Sbjct: 3194 AQKQVEVIVDTGAMAPGAPQVQAEEAE-LTVEAGHTATLRCSATGSPAPTIHWSKLRSPL 3252

Query: 4452 KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGI 4511
                  +  T      LII +V  +DS  +   A +  G A+ +  L VE          
Sbjct: 3253 PWQHRLEGDT------LIIPRVAQQDSGQYICNATSPAGHAEATIILHVES--------- 3297

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
             PP  T   ++ +V +G+ V+L     GT P+   W + G  +  +   RN++L  +   
Sbjct: 3298 -PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFE--- 3353

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP- 4628
                  A P+DSG+Y C   N  G A   A+ +V  P     P     A + P   + P 
Sbjct: 3354 -----RAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP-PGSLPATSIPAGSTPTVQVTPQ 3407

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L+ K +  G ++EF C +       ++W+K    + P        +  +  LRI      
Sbjct: 3408 LETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP------GHSVQDGVLRIQNLDQS 3459

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             +G Y C A+   G+   +A+L V Q   +  +   T ++ +VV  G   +F+       
Sbjct: 3460 CQGTYICQAHGPWGKAQASAQL-VIQALPSVLINIRTSVQTVVV--GHAVEFECLALGDP 3516

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            KP + W + G  +   P   ++  G   V+ I +    D G + C AT AAG  ++   L
Sbjct: 3517 KPQVTWSKVGGHL--RPG--IVQSG--GVVRIAHVELADAGQYRCTATNAAGTTQSHVLL 3570

Query: 4809 VVKS 4812
            +V++
Sbjct: 3571 LVQA 3574



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 106/422 (25%), Positives = 164/422 (38%), Gaps = 57/422 (13%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQI 4459
            +  PV    PP  T  +QP ++     A F     G P P ++W     P    P   QI
Sbjct: 1863 LSAPVVSIHPPQLT--VQPGQL-----AEFRCSATGSPTPTLEW--TGGPGGQLPAKAQI 1913

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            H      IL +  V   D A +   A +  G     A L V      G GG   P   ++
Sbjct: 1914 HG----GILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVH-----GGGG---PRVQVS 1961

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             +   V +G+ VRL  +  G     + W K G  + P  R+   E     TLLI      
Sbjct: 1962 PERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARS---ERTDIATLLIPAITTA 2018

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y CVA + AG A+   + VV L A+   P P    +++P           V EGQ 
Sbjct: 2019 DAGFYLCVATSPAGTAQARIQVVV-LSASDASPPPVKIESSSPS----------VTEGQT 2067

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            ++ +C + G     V WY+    + P      SR      LR+ +  P D G+Y C   N
Sbjct: 2068 LDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSR------LRLPQVSPADSGEYVCRVEN 2121

Query: 4700 SAG----RVTVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKP 4750
             +G     +TV+             +P  T P+R       V EGQ       +  +   
Sbjct: 2122 GSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHA 2181

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             + W + G  +P        H+ + ++L +      D+G + C     +G +E S  + +
Sbjct: 2182 QVTWHKRGGSLPAR------HQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235

Query: 4811 KS 4812
            ++
Sbjct: 2236 EA 2237



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 100/412 (24%), Positives = 148/412 (35%), Gaps = 43/412 (10%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIH 4460
            EG     + P+ +       V + + A F+        P+ ++W   N  ++++    +H
Sbjct: 3013 EGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VH 3068

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                 SI+ I      +   +  VA N  G A+   NL V            PP+ ++  
Sbjct: 3069 ISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG----------PPTVSVLP 3118

Query: 4521 QN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            +  V V  G+ V L+    G       W +         +      D    L I  A P 
Sbjct: 3119 EGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPS 3178

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y C+A N+ G A+   E +V   A      PQ +A  A         +  V  G  
Sbjct: 3179 DAGTYVCLAQNALGTAQKQVEVIVDTGAMA-PGAPQVQAEEA---------ELTVEAGHT 3228

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
                C   G P PT+ W    KL  P  + Q     D  TL I     +D G Y C A +
Sbjct: 3229 ATLRCSATGSPAPTIHW---SKLRSPLPW-QHRLEGD--TLIIPRVAQQDSGQYICNATS 3282

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
             AG       L V  P  A  +P         V  G+  Q +         T QW R G+
Sbjct: 3283 PAGHAEATIILHVESPPYATTVP-----EHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 3337

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P            N +L       ED+G + CR T   G  E  A+L+V+
Sbjct: 3338 SLPGRA------TARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQ 3383



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 77/353 (21%), Positives = 148/353 (41%), Gaps = 32/353 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L + QV   DS  +        GT + S  + ++++        V     + + + ++
Sbjct: 2486 SRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASL 2545

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             +G  + L+  V    P  + W K G  +    R++I+       L I +  P DSG+Y 
Sbjct: 2546 ANGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGS----RLRIPQVTPADSGEYV 2599

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C   N AG    +   +V++  +     P      +PP  IE     +V EGQ ++ +C 
Sbjct: 2600 CHVSNGAGSR--ETSLIVTIQGSGSSHVPSV----SPPIRIESSSPTVV-EGQTLDLNCV 2652

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            +  +P   + WYK G  L  PS++    +T   + LR+ +    D G+Y C A N+   +
Sbjct: 2653 VARQPQAIITWYKRGGSL--PSRH----QTHGSH-LRLHQMSVADSGEYVCRANNNIDAL 2705

Query: 4705 TVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + V+    + + P  + P+R       V EG+       +  +    + W + G 
Sbjct: 2706 EASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG 2765

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +P        H+   + L + +    D+G + CR   ++G +E S  + +++
Sbjct: 2766 SLPSH------HQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEA 2812



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 90/356 (25%), Positives = 148/356 (41%), Gaps = 41/356 (11%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S+L + QV   DS  +        G  + S  + +E     G    +PP   + + +  V
Sbjct: 2201 SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGP---IPP-VRIESSSSTV 2256

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L   V G     V W K G  +    R+++        L I +A P D+G+Y 
Sbjct: 2257 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA--RHQVRGS----RLYIFQASPADAGQYV 2310

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N       +A   V++  T+        A +  P  IEP   + VAEGQ ++ +C 
Sbjct: 2311 CRASNGM-----EASITVTVTGTQGANLAYP-AGSTQPIRIEPSSSQ-VAEGQTLDLNCV 2363

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            + G+    V W+K G  L  P ++           LR+ +A P D G+Y C    S+  V
Sbjct: 2364 VPGQSHAQVTWHKRGGSL--PVRH-----QTHGSLLRLYQASPADSGEYVCRVLGSS--V 2414

Query: 4705 TVAAKLKVTQPDQADNLPAL--TPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWLRE 4757
             + A + VT  + A ++PAL  TP   I      V EGQ       +  +    + W + 
Sbjct: 2415 PLEASVLVTI-EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKR 2473

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            G  +P        H+ + + L +      D+G + CR   ++G  E S  + ++ +
Sbjct: 2474 GGSLPAR------HQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2523



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 100/413 (24%), Positives = 162/413 (39%), Gaps = 45/413 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            S PP+  +   P  V E +         G     + WYR    +   P  Q+H     S 
Sbjct: 2049 SPPPVKIESSSPS-VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLP--PHTQVHG----SR 2101

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT----LTAQNV 4523
            L + QV   DS  +    EN  G  + S  + V      G      P  T    +   + 
Sbjct: 2102 LRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSS 2161

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            +V  GQ + L+  V G     V W K G  +    R+   +  G+  L + +  P DSG+
Sbjct: 2162 HVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RH---QTHGSL-LRLHQVTPADSGE 2215

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C  + ++G    +A  +V++ A+   P P       PP  IE      VAEGQ ++ S
Sbjct: 2216 YVCHVVGTSGPL--EASVLVTIEASVI-PGP------IPPVRIES-SSSTVAEGQTLDLS 2265

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C + G+    V WYK    +      + SR      L I +A P D G Y C A N    
Sbjct: 2266 CVVAGQAHAQVTWYKRGGSLPARHQVRGSR------LYIFQASPADAGQYVCRASNGM-E 2318

Query: 4704 VTVAAKLKVTQ-PDQADNLPALTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
             ++   +  TQ  + A    +  P+R       V EGQ       +  +    + W + G
Sbjct: 2319 ASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG 2378

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              +P      + H+ + ++L +      D+G + CR   ++  +E S  + ++
Sbjct: 2379 GSLP------VRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE 2425



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 95/410 (23%), Positives = 160/410 (39%), Gaps = 52/410 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP  T   +   V   E  + +    G P    +W R    +           +   +L 
Sbjct: 3298 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPG------RATARNELLH 3351

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP----PSFTLTAQNVNV 4525
              +   EDS  +     N+ G+A+  A L+V+          +P    P+  +T Q    
Sbjct: 3352 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3411

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            + G  V     V   +   + W K G ++ P   + +  +DG   +  L+   Q  G Y 
Sbjct: 3412 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPG--HSV--QDGVLRIQNLDQSCQ--GTYI 3465

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI--VAEGQAIEFS 4643
            C A    G+A+  A+ V+                 A P ++  ++  +  V  G A+EF 
Sbjct: 3466 CQAHGPWGKAQASAQLVIQ----------------ALPSVLINIRTSVQTVVVGHAVEFE 3509

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C  +G P P V W K    ++P              +RI+     D G Y+C A N+AG 
Sbjct: 3510 CLALGDPKPQVTWSKVGGHLRP------GIVQSGGVVRIAHVELADAGQYRCTATNAAG- 3562

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             T +  L + Q      LP ++  +++ V  G  A F    +    P I W +    +P 
Sbjct: 3563 TTQSHVLLLVQA-----LPQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLP- 3616

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             PD ++     N +L++ +   +D GT+ C AT   G+V+  A L V  +
Sbjct: 3617 -PDSRL----ENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3661



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 74/305 (24%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V P+  + + +  V  GQ + L+  V G     V W K G  +    R+++    G+  L
Sbjct: 2435 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV---HGS-RL 2488

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             +L+  P DSG+Y C  + S+G    +A  +V++   + +         A P  IE    
Sbjct: 2489 RLLQVTPADSGEYVCRVVGSSGTQ--EASVLVTI---QQRLSGSHSQGVAYPVRIES-SS 2542

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
              +A G  ++ +C +  +   T+ WYK G  L  PS++  +        LRI +  P D 
Sbjct: 2543 ASLANGHTLDLNCLVASQAPHTITWYKRGGSL--PSRHQIVGS-----RLRIPQVTPADS 2595

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQIT 4745
            G+Y C   N AG    +  + + Q   + ++P+++P   I      V EGQ       + 
Sbjct: 2596 GEYVCHVSNGAGSRETSLIVTI-QGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 2654

Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             + +  I W + G  +P        H+ + + L +      D+G + CRA      +E S
Sbjct: 2655 RQPQAIITWYKRGGSLPSR------HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEAS 2708

Query: 4806 AKLVV 4810
              + V
Sbjct: 2709 IVISV 2713



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 79/354 (22%), Positives = 146/354 (41%), Gaps = 33/354 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L I QV   DS  +     N  G+ + S  + ++         + PP   + + +  V
Sbjct: 2583 SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPP-IRIESSSPTV 2641

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L+  V       + W K G  +    R+   +  G++ L + +    DSG+Y 
Sbjct: 2642 VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RH---QTHGSH-LRLHQMSVADSGEYV 2695

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N+      +A  V+S+  +   P   +   ++ P  IE      VAEG+ ++ +C 
Sbjct: 2696 CRANNNIDAL--EASIVISVSPSAGSP---SAPGSSMPIRIESSSSH-VAEGETLDLNCV 2749

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            + G+    V W+K    +      + SR      LR+    P D G+Y C    S+G + 
Sbjct: 2750 VPGQAHAQVTWHKRGGSLPSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLE 2803

Query: 4706 VAAKLKV-TQPDQADNLPA---LTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
             +  + +      A ++PA     P+R       V EGQ    K  +  +    + W + 
Sbjct: 2804 ASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKR 2863

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G  +P        H+ +  +L +      D+G ++C+ T ++G +E S  + ++
Sbjct: 2864 GGNLPAR------HQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIE 2911



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 87/362 (24%), Positives = 140/362 (38%), Gaps = 34/362 (9%)

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP---PSF 4516
            H  +  S L +  V   DS  +        G  + S  + +E           P   P  
Sbjct: 2770 HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPI 2829

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
             +   +  V  GQ + L   V G     V W K G  +    R+++    G   L + + 
Sbjct: 2830 RIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPA--RHQV---HGPL-LRLNQV 2883

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
             P DSG+Y C    S+G    +A  +V++  +   P P    A   P  IE      V E
Sbjct: 2884 SPADSGEYSCQVTGSSGTL--EASVLVTIEPSSPGPIPAPGLAQ--PIYIEASSSH-VTE 2938

Query: 4637 GQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            GQ ++ +C + G+    V WYK G  L  P+++           LR+    P D G+Y C
Sbjct: 2939 GQTLDLNCVVPGQAHAQVTWYKRGGSL--PARH-----QTHGSQLRLHLVSPADSGEYVC 2991

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQITSKIKP 4750
             A +  G    A+      P +  +    +P+  I      V +GQ A FK  I     P
Sbjct: 2992 RAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAP 3051

Query: 4751 -TIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +++W      + +      +H   N +++ I  T   + GT+ C A+ A G  ++   L
Sbjct: 3052 ISLEWKTRNQELEDN-----VHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNL 3106

Query: 4809 VV 4810
             V
Sbjct: 3107 SV 3108



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 30/292 (10%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V  GQ + L+  V G     V W K G  +   +R+   +  G+  L + +A P DSG+Y
Sbjct: 2352 VAEGQTLDLNCVVPGQSHAQVTWHKRGGSLP--VRH---QTHGSL-LRLYQASPADSGEY 2405

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C  + S+     +A  +V++     +P     A    P +        VAEGQ ++ +C
Sbjct: 2406 VCRVLGSS--VPLEASVLVTI-----EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNC 2458

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             + G+    V W+K    +        SR      LR+ +  P D G+Y C    S+G  
Sbjct: 2459 LVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSGEYVCRVVGSSGTQ 2512

Query: 4705 TVAAKLKVTQ-----PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + + Q       Q    P         +  G        + S+   TI W + G 
Sbjct: 2513 EASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGG 2572

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P        H+   + L I      D+G + C  +  AG  ETS  + ++
Sbjct: 2573 SLPSR------HQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2618



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 103/486 (21%), Positives = 168/486 (34%), Gaps = 54/486 (11%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A+F     G+PTP + WT      +           Q     L +  + P D+ +Y 
Sbjct: 1880 GQLAEFRCSATGSPTPTLEWTGGPGGQLPAKA-------QIHGGILRLPAVEPTDQAQYL 1932

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH--KAYGTQGYTTEQSRQ 203
            C A +  G+ +    +   G               H   TV    +A G    T    ++
Sbjct: 1933 CRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE 1992

Query: 204  TQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
               +     ++ +      +         +  F   +     G +  +I   +  S    
Sbjct: 1993 GGSLPPQARSERTDIATLLIPAIT---TADAGFYLCVATSPAGTAQARIQVVV-LSASDA 2048

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP +  +  +  + EG        ++G+   +VTW++ G  L     H   T  + + L
Sbjct: 2049 SPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSL---PPH---TQVHGSRL 2102

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            R+     +DSG Y    EN +G    S  ++V   T S          T         RI
Sbjct: 2103 RLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHS------GPSYTPVPGSTRPIRI 2156

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            E S                V EG+    +C V G+ + +VTW      +   +       
Sbjct: 2157 EPSSS-------------HVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARH------- 2196

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--STLN 501
            ++    L +  VT +DSG   C     SG       L  IE   +  P    R   S+  
Sbjct: 2197 QTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSST 2255

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + L+    G    ++TW K G  +    ++R       S L I +A  +DA  Y
Sbjct: 2256 VAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVR------GSRLYIFQASPADAGQY 2309

Query: 562  QCTAQN 567
             C A N
Sbjct: 2310 VCRASN 2315



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 56/177 (31%), Positives = 74/177 (41%), Gaps = 21/177 (11%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G    F+C   G P P+VTW      +R       +V   G   + I +V L+D+G 
Sbjct: 3500 VVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG-----IVQSGG--VVRIAHVELADAGQ 3552

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A N +G T     L V    Q+  P+ V       V  G   V    A G PTP I
Sbjct: 3553 YRCTATNAAGTTQSHVLLLVQALPQISMPQEV------RVPAGSAAVFPCIASGYPTPDI 3606

Query: 523  TWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +W K DG   +P P+ R+      + L +P  +  DA  Y CTA N  G     A L
Sbjct: 3607 SWSKLDG--SLP-PDSRLEN----NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHL 3656



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 45/177 (25%), Positives = 77/177 (43%), Gaps = 11/177 (6%)

Query: 395  VKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            V+V  +R  V  G+  R  CR  G P   +TW    R+       +     +    L+I 
Sbjct: 1958 VQVSPERTQVHAGRTVRLYCRAAGVPSATITW----RKEGGSLPPQARSERTDIATLLIP 2013

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
             +T +D+G   CVA + +G    + ++ V+       P      S+ +V EG+ + LN  
Sbjct: 2014 AITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCV 2073

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G+   ++TW + G  + P      HT    S L +P+   +D+  Y C  +N +G
Sbjct: 2074 VAGSAHAQVTWYRRGGSLPP------HTQVHGSRLRLPQVSPADSGEYVCRVENGSG 2124



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 112/531 (21%), Positives = 179/531 (33%), Gaps = 67/531 (12%)

Query: 52   VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
            +E+SG    +    PG   P   E    ++R A+G     +  + G     V+W ++   
Sbjct: 2810 IEASGS-SAVHVPAPGGAPPIRIEP--SSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGN 2866

Query: 112  LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXX 171
            L            Q     L + Q+ P D GEY+C      G    SV +  E       
Sbjct: 2867 LPA--------RHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPI 2918

Query: 172  XXXXXXXYRHVSETVEHKAYGTQ---GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEY 228
                     ++  +  H   G               Q   Y  G    +           
Sbjct: 2919 PAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRL 2978

Query: 229  RLLREVSFRESITKRYVG---ESDVQISTEIDRSLGP---VSPPKIAQKPRNSKLQEGAD 282
             L+      E + +   G   E +   +  +  S G    +  P I+  P +S +Q+G D
Sbjct: 2979 HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQD 3038

Query: 283  AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            A F+  +     P    +K   + +  N H    + N + + +  T+ S+ G Y      
Sbjct: 3039 ASFKCLIHDGAAPISLEWKTRNQELEDNVH---ISPNGSIITIVGTRPSNHGTYR----- 3090

Query: 343  PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
               C+ ++ Y   +S     V    +                +S     P +VKV     
Sbjct: 3091 ---CVASNAYGVAQSVVNLSVHGPPT----------------VSVLPEGPVWVKV----- 3126

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHA-LMITNVTLSDS 460
               GK    +C   G P     W  I+    + +     L++   +HA L I++   SD+
Sbjct: 3127 ---GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMD---SHAVLQISSAKPSDA 3180

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
            G   C+A+N  G    Q  + V        AP+     + L V  G    L   A G+P 
Sbjct: 3181 GTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPA 3240

Query: 520  PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P I W K   P+     L         TL IPR    D+  Y C A + AG
Sbjct: 3241 PTIHWSKLRSPLPWQHRLE------GDTLIIPRVAQQDSGQYICNATSPAG 3285



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 80/315 (25%), Positives = 109/315 (34%), Gaps = 41/315 (13%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP     P ++ +Q G   Q Q    G P     W + G  L          T  +  L
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGR------ATARNELL 3350

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG Y     N  G       L V+ P  S          T T Q       
Sbjct: 3351 HFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ------- 3403

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
                  + PQ     + + +  G    F C V      ++ WF    Q+     H +   
Sbjct: 3404 ------VTPQL----ETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP--GHSV--- 3446

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            + G   L I N+  S  G   C A    G+     +L VI+    V      R S   V 
Sbjct: 3447 QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQASAQL-VIQALPSVLINI--RTSVQTVV 3501

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             G  V     A+G P P++TW K G  + P     I   GG   + I   + +DA  Y+C
Sbjct: 3502 VGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGG--VVRIAHVELADAGQYRC 3555

Query: 564  TAQNVAGSTATRARL 578
            TA N AG+T +   L
Sbjct: 3556 TATNAAGTTQSHVLL 3570



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 115/528 (21%), Positives = 187/528 (35%), Gaps = 68/528 (12%)

Query: 62   TAGRPGEPSPPIFEQI-FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            +AG P  P   +  +I   ++  A+G        + G     V+W ++          S+
Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG--------SL 2767

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXX 178
              + QT    L +  + P D GEY C      G  EA   V I+  G             
Sbjct: 2768 PSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAP 2827

Query: 179  YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV-DTFEYRLLR--EVS 235
               +  +    A   +G T +        A+   T H    +          LLR  +VS
Sbjct: 2828 PIRIEPSSSRVA---EGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVS 2884

Query: 236  FRES--ITKRYVGES---DVQISTEIDRSL-GPVSPPKIAQ----KPRNSKLQEGADAQF 285
              +S   + +  G S   +  +   I+ S  GP+  P +AQ    +  +S + EG     
Sbjct: 2885 PADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2944

Query: 286  QVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               + G    +VTW+K G  L    +H+   TH  + LR+     +DSG Y   A +  G
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSL--PARHQ---THG-SQLRLHLVSPADSGEYVCRAASGPG 2998

Query: 346  CIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTE 405
                + +     P+E      RS  I+      T                       V +
Sbjct: 2999 PEQEASFTVTVPPSEGSSYRLRSPVISIDPPSST-----------------------VQQ 3035

Query: 406  GKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
            G+   F C +     P  + W   ++++ D+ +    ++ +G+  + I     S+ G   
Sbjct: 3036 GQDASFKCLIHDGAAPISLEWKTRNQELEDNVH----ISPNGS-IITIVGTRPSNHGTYR 3090

Query: 465  CVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
            CVA N  G       L+V     V V P+       + V+ G+ V L   + G P     
Sbjct: 3091 CVASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVWVKVGKAVTLECVSAGEPRSSAR 3145

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            W +         +         + L I  AK SDA  Y C AQN  G+
Sbjct: 3146 WTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGT 3193



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 5/133 (3%)

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            N  L I NV LSD+G   C   N          L+V     + AP        L V+ G+
Sbjct: 1822 NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQ 1881

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
                   A G+PTP + W       +P  + +IH  GG   L +P  + +D A Y C A 
Sbjct: 1882 LAEFRCSATGSPTPTLEWTGGPGGQLP-AKAQIH--GG--ILRLPAVEPTDQAQYLCRAH 1936

Query: 567  NVAGSTATRARLY 579
            + AG    RA L+
Sbjct: 1937 SSAGQQVARAVLH 1949



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 12/176 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G++  F C  TG P P + W             K  ++      L +  V  +D   
Sbjct: 1877 VQPGQLAEFRCSATGSPTPTLEWTGGPG---GQLPAKAQIHGG---ILRLPAVEPTDQAQ 1930

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A + +G+   +  L+V        P+         V  G  V L  RA G P+  I
Sbjct: 1931 YLCRAHSSAGQQVARAVLHV---HGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATI 1987

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            TW+K+G  + P       TD   +TL IP    +DA +Y C A + AG+   R ++
Sbjct: 1988 TWRKEGGSLPPQARSE-RTD--IATLLIPAITTADAGFYLCVATSPAGTAQARIQV 2040



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 53/231 (22%), Positives = 82/231 (35%), Gaps = 20/231 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H++          L +L     DSG
Sbjct: 2448 VAEGQTL--DLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSG 2499

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CR     G  E SV +    +  G   +   +   IE     L +G +    C V  
Sbjct: 2500 EYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVA- 2558

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
                   I WY  G  +   +R + V       L I      DSGEYVC   N  G   T
Sbjct: 2559 -SQAPHTITWYKRGGSL--PSRHQIVGSR----LRIPQVTPADSGEYVCHVSNGAGSRET 2611

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
               +   G G  ++ S+ P    +      ++G         + +P   IT
Sbjct: 2612 SLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIIT 2662



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 14/173 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + +GQ A ++  LI  G   + +EW    + +E +  I    +    ++ I+GT+ ++ G
Sbjct: 3033 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHG 3087

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
            TY C A+N +G A+  V L     S    P  +   +    +K G++   EC  V   +P
Sbjct: 3088 TYRCVASNAYGVAQSVVNL-----SVHGPPTVSVLPEGPVWVKVGKAVTLEC--VSAGEP 3140

Query: 3180 DMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                 W   +  P +   R   + D    VL I+  +  D+G YVC A N  G
Sbjct: 3141 RSSARWTRISSTPAKLEQRTYGLMD-SHAVLQISSAKPSDAGTYVCLAQNALG 3192



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 8/140 (5%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I   + +D+GTY C  +N +   + +  L          P  + H   +  ++ GQ 
Sbjct: 1824 ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT-VQPGQL 1882

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A F C+      P   +EW   G P     ++   +     +L +   +  D  +Y+CRA
Sbjct: 1883 AEFRCSAT--GSPTPTLEW--TGGP---GGQLPAKAQIHGGILRLPAVEPTDQAQYLCRA 1935

Query: 3227 YNKYGEDFTRATINCYGKGG 3246
            ++  G+   RA ++ +G GG
Sbjct: 1936 HSSAGQQVARAVLHVHGGGG 1955



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 80/320 (25%), Positives = 123/320 (38%), Gaps = 52/320 (16%)

Query: 261  GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
            G   P +I  +P +S++ EG        + G    +VTW K G  L    +H+   TH  
Sbjct: 2338 GSTQPIRI--EPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSL--PVRHQ---THG- 2389

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
            + LR+     +DSG Y       +  +  S  + +E P  S      +  +T T      
Sbjct: 2390 SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVP----ALGVTPTV----- 2439

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
             RIE S   +A             EG+    +C V G+ + +VTW      +     H++
Sbjct: 2440 -RIESSSSQVA-------------EGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV 2483

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGE------TAFQCRLNVIEKEQVVAPKFV 494
                 G+  L +  VT +DSG   C     SG          Q RL+    + V  P  +
Sbjct: 2484 ----HGSR-LRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRI 2538

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
            E  S+ ++  G  + LN          ITW K G  +    ++        S L IP+  
Sbjct: 2539 ES-SSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI------VGSRLRIPQVT 2591

Query: 555  ASDAAWYQCTAQNVAGSTAT 574
             +D+  Y C   N AGS  T
Sbjct: 2592 PADSGEYVCHVSNGAGSRET 2611



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 11/125 (8%)

Query: 4583 KYECVAINSAGEA--RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQA 4639
            ++ CV+ N    A   CD E         D P    +    PP+++ P ++ I A  GQ 
Sbjct: 372  QFRCVSTNMCIPASFHCDEE--------SDCPDRSDEFGCMPPQVVTPPRESIQASRGQT 423

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            + F+C  +G P P + W      I       ++      TL I +    D+G Y C A N
Sbjct: 424  VTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMN 483

Query: 4700 SAGRV 4704
            + G V
Sbjct: 484  ARGMV 488



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 24/72 (33%), Positives = 35/72 (48%)

Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           ++    G+ V     A+G PTP I W+ +   I  +P + + ++GG  TL I   K SD 
Sbjct: 415 SIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQ 474

Query: 559 AWYQCTAQNVAG 570
             Y C A N  G
Sbjct: 475 GAYTCEAMNARG 486



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 60/246 (24%), Positives = 95/246 (38%), Gaps = 42/246 (17%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E TI     +PP +   + ++  V  G  V   C     G P +   W   G       R
Sbjct: 3288 EATIILHVESPP-YATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLP--GR 3342

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
                N+     L  +     D+G Y CR TNK GSA   A++        +  + +P G 
Sbjct: 3343 ATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGS 3398

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            +                   P V   P    Q+++ ++  S  V F C V      +LR 
Sbjct: 3399 T-------------------PTVQVTP----QLETKSIGAS--VEFHCAVPSDRGTQLR- 3432

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             W++ G  LP GH   +V D G + +  L    +  G YIC+A   +G+    A +  + 
Sbjct: 3433 -WFKEGGQLPPGH---SVQD-GVLRIQNLDQSCQ--GTYICQAHGPWGKAQASAQLVIQA 3485

Query: 3924 LPDIIL 3929
            LP +++
Sbjct: 3486 LPSVLI 3491



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 2377 VFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSM 2436
            V T P ++I     GQT  F C  + +G PT  + W  N   I    R+T T + G  ++
Sbjct: 408  VVTPPRESIQ-ASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464

Query: 2437 TISHVRDEDEGVYMCRASNLLG 2458
             I  V++ D+G Y C A N  G
Sbjct: 465  IIRDVKESDQGAYTCEAMNARG 486



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/278 (20%), Positives = 105/278 (37%), Gaps = 24/278 (8%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A       G+P P + W++ ++PL   ++         GD +L+I ++   D G+Y 
Sbjct: 3226 GHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLE-------GD-TLIIPRVAQQDSGQYI 3277

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQ 205
            C A +  G A  ++ +  E                  +  ++  A+GT   T + SR   
Sbjct: 3278 CNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 3337

Query: 206  KVAYTNGTDHSSTDDFK----VDTFEY--RLLREVSFRESITKRYVGESDVQISTEIDRS 259
             +     T  +    F+     D+  Y  R+  +V   E+  +  V      +      S
Sbjct: 3338 SLP-GRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPA---TS 3393

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            +   S P +   P+      GA  +F   +  +   ++ WFK G +L     H +     
Sbjct: 3394 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQL--PPGHSV----Q 3447

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
               LR++N  +S  G Y   A  P G    S  L +++
Sbjct: 3448 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQA 3485



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 18/155 (11%)

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
            D+   + WF  G  +   H ++        VL I     +  GTY C+A   WG+A+ S 
Sbjct: 3426 DRGTQLRWFKEGGQLPPGHSVQDG------VLRIQNLDQSCQGTYICQAHGPWGKAQASA 3479

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +L  +           T +Q +     G +  FEC  + + DP  ++ W   G  +R   
Sbjct: 3480 QL-VIQALPSVLINIRTSVQTV---VVGHAVEFEC--LALGDPKPQVTWSKVGGHLRPG- 3532

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                V   G  V+ IA+ +  D+G+Y C A N  G
Sbjct: 3533 ---IVQSGG--VVRIAHVELADAGQYRCTATNAAG 3562



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 56/240 (23%), Positives = 91/240 (37%), Gaps = 44/240 (18%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            ++P +   +    +++ GE    +     T  P L  +W   G SL   +  R       
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARN------ 3347

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537
             +L      PEDSG Y CR  N  G A   A + VQG    +  + +P G   T+     
Sbjct: 3348 ELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ---- 3403

Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
                      +TP+ E+               S  +S  F C  +P +D   ++ WF  G
Sbjct: 3404 ----------VTPQLET--------------KSIGASVEFHC-AVP-SDRGTQLRWFKEG 3437

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
              L  G  V+        +L I  + Q   G Y C+A    G+A  S +L ++    +++
Sbjct: 3438 GQLPPGHSVQD------GVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLI 3491



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + S +  G     + W+  G ++ A H++R    +      I      D+G
Sbjct: 2256 VAEGQTL--DLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLY------IFQASPADAG 2307

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CRA+N   +A I+V +     +    P  +T    IE     + +GQ+    C VVP
Sbjct: 2308 QYVCRASNGM-EASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC-VVP 2365

Query: 3176 VDDPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                  ++ W+  G   P+RH T           +L +      DSGEYVCR
Sbjct: 2366 -GQSHAQVTWHKRGGSLPVRHQTHGS--------LLRLYQASPADSGEYVCR 2408



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 59/239 (24%), Positives = 87/239 (36%), Gaps = 19/239 (7%)

Query: 4581 SGKYECVAINSAGEARCDAEC---VVSLPATKD-KPKPQTKAANAPPEIIEPLKDKIVAE 4636
            +G Y C A       +   +C    V  P+ +  +  P+T  A    E+  P +  IV +
Sbjct: 1633 AGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEV-HPARS-IVPQ 1690

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G +    C++ G P     W + D    PS   Q  + ++   L      P D G Y C 
Sbjct: 1691 GGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSE---LHFPSVQPSDAGVYICT 1747

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP-TIQWL 4755
              N     T  A+L VT+         +   R   V  G    F     SK    T+ W 
Sbjct: 1748 CRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWT 1807

Query: 4756 R--EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            R   G L     DF       N +L I N    D GT+ C  +      + +A L V++
Sbjct: 1808 RLHNGKLPTRAMDF-------NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQA 1859



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 25/181 (13%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    +  ++P G     + W   G  + A H++         +L +      DSG
Sbjct: 2838 VAEGQTLDLKC-VVP-GQAHAQVTWHKRGGNLPARHQVHGP------LLRLNQVSPADSG 2889

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKP----RFTTHIQ-NIEGLKDGQSAHFECTVV 3174
             YSC+ T   G  E SV +     S G  P        +I+ +   + +GQ+    C VV
Sbjct: 2890 EYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VV 2948

Query: 3175 PVDDPDMKIEWYHNG--QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P      ++ WY  G   P RH T            L +      DSGEYVCRA +  G 
Sbjct: 2949 P-GQAHAQVTWYKRGGSLPARHQTHGSQ--------LRLHLVSPADSGEYVCRAASGPGP 2999

Query: 3233 D 3233
            +
Sbjct: 3000 E 3000



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 6/116 (5%)

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADN---LP--ALTPLRD-IVVYEGQPAQFKTQITS 4746
            ++CV+ N     +     +   PD++D    +P   +TP R+ I    GQ   F      
Sbjct: 373  FRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIG 432

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
               P I W      IP  P   +  EG    L+I +  E D G +TC A  A G V
Sbjct: 433  VPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMV 488



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 17/188 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W+  G ++ A H+           L +      DSG
Sbjct: 2936 VTEGQTL--DLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQ------LRLHLVSPADSG 2987

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE----GLKDGQSAHFECTVVP 3175
             Y CRA +  G  + +     V  S+G   R  + + +I+     ++ GQ A F+C +  
Sbjct: 2988 EYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHD 3047

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               P + +EW    Q +  +  I         ++ I  T+  + G Y C A N YG   +
Sbjct: 3048 GAAP-ISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHGTYRCVASNAYGVAQS 3102

Query: 3236 RATINCYG 3243
               ++ +G
Sbjct: 3103 VVNLSVHG 3110



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/306 (24%), Positives = 118/306 (38%), Gaps = 46/306 (15%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P +  +  +S++ EG        ++G    +VTW K G  L    +H++    + + LR+
Sbjct: 2437 PTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV----HGSRLRL 2490

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
                 +DSG Y         C V       E+     +Q + S   + +Q      RIE 
Sbjct: 2491 LQVTPADSGEYV--------CRVVGSSGTQEASVLVTIQQRLSG--SHSQGVAYPVRIES 2540

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            S  +LA              G     +C V  +    +TW+     +     H+I+ +  
Sbjct: 2541 SSASLA-------------NGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGSR- 2584

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQV--VAPKFVERFSTLN 501
                L I  VT +DSG   C   N +G  ET+    +       V  V+P      S+  
Sbjct: 2585 ----LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPT 2640

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + LN      P   ITW K G   +P+   R  T G  S L + +   +D+  Y
Sbjct: 2641 VVEGQTLDLNCVVARQPQAIITWYKRG-GSLPS---RHQTHG--SHLRLHQMSVADSGEY 2694

Query: 562  QCTAQN 567
             C A N
Sbjct: 2695 VCRANN 2700



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 55/212 (25%), Positives = 79/212 (37%), Gaps = 19/212 (8%)

Query: 368  SQYITDTQQRETEERIEISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
            +Q    T Q++ E  ++    A  APQ      +  V  G      C  TG P P + W 
Sbjct: 3187 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW- 3245

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
             +  +    + H++     G+  L+I  V   DSG   C A + +G       L+V  + 
Sbjct: 3246 -SKLRSPLPWQHRL----EGD-TLIIPRVAQQDSGQYICNATSPAGHAEATIILHV--ES 3297

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
               A    E  S   V+ GE V L   A GTP     W + G  +      R        
Sbjct: 3298 PPYATTVPEHAS---VQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR------NE 3348

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             L   RA   D+  Y+C   N  GS    A+L
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQL 3380



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 39/165 (23%), Positives = 61/165 (36%), Gaps = 12/165 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S  I W   G ++    R        +  L I    T D+G Y C AT+  G A+  
Sbjct: 1981 GVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCVATSPAGTAQAR 2037

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
            +++  +  S    P       +   + +GQ+    C V        ++ WY  G  +   
Sbjct: 2038 IQVVVLSASDASPPPVKIE-SSSPSVTEGQTLDLNCVV--AGSAHAQVTWYRRGGSLPPH 2094

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
            T++          L +      DSGEYVCR  N  G      T++
Sbjct: 2095 TQVHGSR------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2133



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 8/108 (7%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            + P + T +    S+   ET + +C LA  G P +  +W   G  L    R T   +   
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQC-LAH-GTPPLTFQWSRVGSSL--PGRATARNEL-- 3349

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP 4078
              ++F    PEDSG Y CR TN  G  E  A +   G PG +  + +P
Sbjct: 3350 --LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIP 3395



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 46/153 (30%), Positives = 61/153 (39%), Gaps = 23/153 (15%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+  G ++ + H+I      G   L I      DSG Y C  +N  G  E S+ +   
Sbjct: 2565 ITWYKRGGSLPSRHQI-----VGSR-LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2618

Query: 3142 DKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQ--PMRHS 3195
                   P  +  I+ IE     + +GQ+    C V     P   I WY  G   P RH 
Sbjct: 2619 GSGSSHVPSVSPPIR-IESSSPTVVEGQTLDLNCVVAR--QPQAIITWYKRGGSLPSRHQ 2675

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            T     S      + +A     DSGEYVCRA N
Sbjct: 2676 TH---GSHLRLHQMSVA-----DSGEYVCRANN 2700



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 29/218 (13%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            +I W+  G ++ + H+    +      L +      DSG Y CRA N     E S+ +  
Sbjct: 2660 IITWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVIS- 2712

Query: 3141 VDKSKG--QKPRFTTHIQ---NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG--QPMR 3193
            V  S G    P  +  I+   +   + +G++    C VVP      ++ W+  G   P  
Sbjct: 2713 VSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC-VVP-GQAHAQVTWHKRGGSLPSH 2770

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATINCYGKGGVYLES 3251
            H TR           L + +    DSGEYVCR     G  E     TI   G   V++ +
Sbjct: 2771 HQTRGSR--------LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPA 2822

Query: 3252 LQPDSLAKIR-ELESLQGAQQQTPSTPSAEPPKFITQI 3288
              P     IR E  S + A+ QT       P +   Q+
Sbjct: 2823 --PGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQV 2858



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQ 3165
            VL+I   K +D+GTY C A N  G A+  V++  VD             +  E  ++ G 
Sbjct: 3169 VLQISSAKPSDAGTYVCLAQNALGTAQKQVEV-IVDTGAMAPGAPQVQAEEAELTVEAGH 3227

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A   C+      P   I W     P+    R++   D     L I      DSG+Y+C 
Sbjct: 3228 TATLRCSA--TGSPAPTIHWSKLRSPLPWQHRLE--GD----TLIIPRVAQQDSGQYICN 3279

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
            A +  G     ATI  + +   Y  ++   +  +  E   LQ     TP
Sbjct: 3280 ATSPAGH--AEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTP 3326



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/52 (42%), Positives = 27/52 (51%)

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAF 2996
            I W  N   +    R  +TS+ G  TL + DV E D G YTC+A N RG  F
Sbjct: 438  INWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVF 489



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 52/218 (23%), Positives = 76/218 (34%), Gaps = 13/218 (5%)

Query: 385  ISEKALAPQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWFIND-RQIRDDYNHKILV 442
            + E   AP  V+V   R +  +G      C+V+G P     W   D R +      +   
Sbjct: 1669 LPETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQG 1728

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +E     L   +V  SD+GV  C  RN       +  L V E         VE   + +V
Sbjct: 1729 SE-----LHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSV 1783

Query: 503  REGEPVVLNARAVG-TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            R G  V     A   +P   + W +     + N +L          L I   + SDA  Y
Sbjct: 1784 RPGADVTFICTAKSKSPAYTLVWTR-----LHNGKLPTRAMDFNGILTIRNVQLSDAGTY 1838

Query: 562  QCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPT 599
             CT  N+       A L+             +H P+ T
Sbjct: 1839 VCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT 1876



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 56/276 (20%), Positives = 97/276 (35%), Gaps = 14/276 (5%)

Query: 85   QGGNAKFEGKLRGNPTPV-VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
            QG +A F+  +     P+ + W  +   L E N +        G + + I    P + G 
Sbjct: 3035 QGQDASFKCLIHDGAAPISLEWKTRNQEL-EDNVHI----SPNGSI-ITIVGTRPSNHGT 3088

Query: 144  YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR-HVSETVEHKAYGTQGYTTEQSR 202
            Y C A N YG A   V +   G              +   + T+E  + G    +   +R
Sbjct: 3089 YRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTR 3148

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262
             +   A      +   D   V         +      + +  +G +  Q+   +D     
Sbjct: 3149 ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMA 3208

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
               P++  +     ++ G  A  +   +G+P P + W K    L   ++ E        T
Sbjct: 3209 PGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLE------GDT 3262

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L +    + DSG Y   A +P G    +  L VESP
Sbjct: 3263 LIIPRVAQQDSGQYICNATSPAGHAEATIILHVESP 3298



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 12/117 (10%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            T+  + +  +AL PQ + + Q+  V  G    F C  +G P P+++W   D  +  D   
Sbjct: 3564 TQSHVLLLVQAL-PQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPD--- 3618

Query: 439  KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
                +   N+ LM+ +V   D+G   C A N+ G+      L V E+   V P F +
Sbjct: 3619 ----SRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER---VVPYFTQ 3668



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 1/84 (1%)

Query: 265 PPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           PP++   PR S +   G    F     G P P + W  N   + +  +  + +     TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464

Query: 324 RVRNTQKSDSGHYTLLAENPNGCI 347
            +R+ ++SD G YT  A N  G +
Sbjct: 465 IIRDVKESDQGAYTCEAMNARGMV 488



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 55/218 (25%), Positives = 79/218 (36%), Gaps = 27/218 (12%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H+          +L +      DSG
Sbjct: 2163 VAEGQTL--DLNCVVPGQAHAQVTWHKRGGSLPARHQTHGS------LLRLHQVTPADSG 2214

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDD 3178
             Y C      G  E SV L  ++ S    P     I++    + +GQ+    C V     
Sbjct: 2215 EYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA--GQ 2271

Query: 3179 PDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
               ++ WY  G   P RH  R           L I      D+G+YVCRA N      T 
Sbjct: 2272 AHAQVTWYKRGGSLPARHQVRGSR--------LYIFQASPADAGQYVCRASNGMEASITV 2323

Query: 3237 ATINCYGKGGVY-LESLQPDSLAKIRELESLQGAQQQT 3273
                  G    Y   S QP  +    E  S Q A+ QT
Sbjct: 2324 TVTGTQGANLAYPAGSTQPIRI----EPSSSQVAEGQT 2357



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 62/267 (23%), Positives = 97/267 (36%), Gaps = 46/267 (17%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            DSG Y C AT+  G AE ++ L        + P + T +     ++ G++   +C  +  
Sbjct: 3272 DSGQYICNATSPAGHAEATIILHV------ESPPYATTVPEHASVQAGETVQLQC--LAH 3323

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P +  +W   G  +      +        +L        DSG Y CR  NK G     
Sbjct: 3324 GTPPLTFQWSRVGSSLPGRATARNE------LLHFERAAPEDSGRYRCRVTNKVGSAEAF 3377

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +   G  G                  SL        STP+ +    +T  Q  TK + 
Sbjct: 3378 AQLLVQGPPG------------------SLPATSIPAGSTPTVQ----VTP-QLETKSI- 3413

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356
            G S  F    VP  D   ++ WF  G +LP GH  +        +L I    +   G Y 
Sbjct: 3414 GASVEFHC-AVP-SDRGTQLRWFKEGGQLPPGHSVQD------GVLRIQNLDQSCQGTYI 3465

Query: 3357 CVATNKLGRDSTKANLKCTSKENLILD 3383
            C A    G+    A L   +  +++++
Sbjct: 3466 CQAHGPWGKAQASAQLVIQALPSVLIN 3492



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 636 PPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPQ + P + S+ A  G  + F      +G PT  I W  N   I +  R T     G  
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG 462

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGV 719
           +L +  +   D G YTC A++A G+
Sbjct: 463 TLIIRDVKESDQGAYTCEAMNARGM 487



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
            V T P + I+ +  Q   F    + +G P   + W  N   I +  R+T   + G   L 
Sbjct: 408  VVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 465

Query: 1772 MKYVNPEDSGTYTCRAINELG 1792
            ++ V   D G YTC A+N  G
Sbjct: 466  IRDVKESDQGAYTCEAMNARG 486



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + S  P    +  S TV E + +   C V     P+  I WY+ G  LPS H+    +  
Sbjct: 2625 VPSVSPPIRIESSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH-- 2680

Query: 3885 GFVSLDILYVYAEDSGEYICRAVND 3909
                L +  +   DSGEY+CRA N+
Sbjct: 2681 ----LRLHQMSVADSGEYVCRANNN 2701



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 55/239 (23%), Positives = 89/239 (37%), Gaps = 44/239 (18%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            +S   + EG      C V     P   I W+  G  + + H+   +H      L +    
Sbjct: 2636 SSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH------LRLHQMS 2687

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE 2235
              DSG Y+C+A N +           A   +I++      G        A G S  I +E
Sbjct: 2688 VADSGEYVCRANNNID----------ALEASIVISVSPSAGSPS-----APGSSMPIRIE 2732

Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295
                           ++HV EG+T    C V      + ++ ++  G +L S    H T 
Sbjct: 2733 S-------------SSSHVAEGETLDLNCVVPG--QAHAQVTWHKRGGSLPS---HHQTR 2774

Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  L + H  P D+GEY  + + + G   +++ +T+ A GS       P G   IR
Sbjct: 2775 GS---RLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIR 2830



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 390 LAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           + PQ V   ++    + G+   F C   G P P + W +N   I   +    + +E G  
Sbjct: 404 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHI-PSHPRVTVTSEGGRG 462

Query: 449 ALMITNVTLSDSGVVTCVARNKSG 472
            L+I +V  SD G  TC A N  G
Sbjct: 463 TLIIRDVKESDQGAYTCEAMNARG 486



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 62/244 (25%), Positives = 91/244 (37%), Gaps = 46/244 (18%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            + +     +PP   +E   +  V EG  +  +C V   G    ++ W+  G      ++V
Sbjct: 2041 VVLSASDASPPPVKIE-SSSPSVTEGQTLDLNCVV--AGSAHAQVTWYRRGGSLPPHTQV 2097

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
            H         L +  +   D+GEY CR  N  GS    A IT S     VL         
Sbjct: 2098 HGSR------LRLPQVSPADSGEYVCRVEN--GSGPKEASITVS-----VLHG------- 2137

Query: 3805 GEKIKELERGRISDAPKEEPIV-STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
                           P   P+  ST P  I    SH V E + +   C V P +    ++
Sbjct: 2138 -----------THSGPSYTPVPGSTRPIRIEPSSSH-VAEGQTLDLNC-VVPGQ-AHAQV 2183

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKATISC 3921
             W++ G  LP+ H+       G + L +  V   DSGEY+C  V   G  E     TI  
Sbjct: 2184 TWHKRGGSLPARHQTH-----GSL-LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEA 2237

Query: 3922 KKLP 3925
              +P
Sbjct: 2238 SVIP 2241



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 2495 ERRSEEPDREFEKPIFT-QVLTGPSELWEGQHAHYEA-RVVPVGDPSLRFEWYINGVELK 2552
            +  S+ PDR  E      QV+T P E  +           V +G P+    W +N   + 
Sbjct: 389  DEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIP 448

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
               R   T + G  TL I  V  +D G Y C+A+N  G
Sbjct: 449  SHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 1/90 (1%)

Query: 4505 RQGRGGIVPPSF-TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
            R    G +PP   T   +++  + GQ V       G     + W  N   +    R  + 
Sbjct: 397  RSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVT 456

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
             E G  TL+I +    D G Y C A+N+ G
Sbjct: 457  SEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR-NGVPIEASNRLTTMHDFGYVAL 1770
            V  +P   + V   +A   E   +  G+P+    W R +  P +   R   + D  +  L
Sbjct: 3114 VSVLPEGPVWVKVGKAVTLEC--VSAGEPRSSARWTRISSTPAKLEQRTYGLMD-SHAVL 3170

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +    P D+GTY C A N LG A     + V + A
Sbjct: 3171 QISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGA 3206



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 5/99 (5%)

Query: 3035 EPGQQPD--DDTG-RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI 3091
            E    PD  D+ G  PP+  T  ++ +  S GQ   +  + +  G  + +I W  N   I
Sbjct: 390  EESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTF--TCVAIGVPTPIINWRLNWGHI 447

Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
             +  R+      G   L I   K +D G Y+C A N  G
Sbjct: 448  PSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q+GQ A F C LI  G   + +EW    + +ED+  I+         +TI   R  + G
Sbjct: 3033 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGSI----ITIVGTRPSNHG 3087

Query: 2448 VYMCRASNLLG 2458
             Y C ASN  G
Sbjct: 3088 TYRCVASNAYG 3098



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     +++I    G  V F C    +G PT  I+W  N     +  RV   ++ G  
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVA--IGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG 462

Query: 3754 ALDIDYIYARDAGEYTCRATNKWG 3777
             L I  +   D G YTC A N  G
Sbjct: 463  TLIIRDVKESDQGAYTCEAMNARG 486



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 38/178 (21%)

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            L + H      L +  V P DSG Y C   N  G   TS  + +Q        S H  ++
Sbjct: 2574 LPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG-----SSHVPSV 2628

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
                ++E SS                        PT + EGQ+    C +     P   +
Sbjct: 2629 SPPIRIESSS------------------------PTVV-EGQTLDLNCVVAR--QPQAII 2661

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             WY  G  L S H+   S+      L +  +   DSGEY C+A NN+    +SI ++V
Sbjct: 2662 TWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+ +T      + S GQ+  + C     P P   + W  N   + S  R   +++ G   
Sbjct: 406  PQVVTPPRESIQASRGQTVTFTCVAIGVPTPI--INWRLNWGHIPSHPRVTVTSEGGRGT 463

Query: 1904 LDILTVYGEDSGEYTCKAINNLG 1926
            L I  V   D G YTC+A+N  G
Sbjct: 464  LIIRDVKESDQGAYTCEAMNARG 486



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 12/122 (9%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI--RAGHRYRTTHDF 2164
            + P + T +    +++ G+    +C       P LT  W   G  +  RA  R    H F
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLPGRATARNELLH-F 3352

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
               A        EDSG Y C+ TNK+G A     L V G    +  T  P G     Q+ 
Sbjct: 3353 ERAA-------PEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3405

Query: 2225 AQ 2226
             Q
Sbjct: 3406 PQ 3407



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 6/66 (9%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P L  +W R G  +    R T  ++     L+ +   PEDSG Y CR  N++G A   
Sbjct: 3324 GTPPLTFQWSRVGSSLPG--RATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAF 3377

Query: 1798 STLFVQ 1803
            + L VQ
Sbjct: 3378 AQLLVQ 3383



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 10/111 (9%)

Query: 3825 IVSTPPKFITQIKS--HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            ++   P  +  I++   TV     V FEC      DPK ++ W + G     GH    + 
Sbjct: 3482 VIQALPSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GHLRPGIV 3534

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
              G V + I +V   D+G+Y C A N  G   +   +  + LP I +  +V
Sbjct: 3535 QSGGV-VRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEV 3584



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 10/110 (9%)

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +EP   +  +  +  V ++  S+   V+EG+ + L C +   G    +V W   G S+  
Sbjct: 2424 IEPAGSVPALGVTPTVRIE--SSSSQVAEGQTLDLNCLVA--GQAHAQVTWHKRGGSLP- 2478

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             +R + +       L ++  T AD+GEY  R V   G+   S +V + +R
Sbjct: 2479 -ARHQVHGS----RLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2523



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 53/231 (22%), Positives = 77/231 (33%), Gaps = 45/231 (19%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P   +     +VAE Q    +   +  G    +V W + G        L   H      L
Sbjct: 2437 PTVRIESSSSQVAEGQT--LDLNCLVAGQAHAQVTWHKRG------GSLPARHQVHGSRL 2488

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +  V P DSG Y CR +   G    S  + +Q +    L   H   +    ++E SS  
Sbjct: 2489 RLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR----LSGSHSQGVAYPVRIESSS-- 2542

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
                                     L+ G +    C +     P+  + WY  G  L S 
Sbjct: 2543 -----------------------ASLANGHTLDLNCLVASQA-PH-TITWYKRGGSLPSR 2577

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            H+   S       L I  V   DSGEY C   N  G   +S+ + +Q   S
Sbjct: 2578 HQIVGSR------LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2622



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 1568 DMVDEVTTQAP-ICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF 1626
            D  DE     P + T   ++++   GQ   F    + +   T  + W  N   + S  R 
Sbjct: 396  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFT--CVAIGVPTPIINWRLNWGHIPSHPRV 453

Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            T T+  G   L I      D G YTC A+NA G
Sbjct: 454  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 2/83 (2%)

Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
           P+  TP ++ I    G    F      IG  T  + W  +   + +  R+T     G   
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGT 463

Query: 969 LTIKSVTVHDAGHYTCRAYNAIG 991
           L I+ V   D G YTC A NA G
Sbjct: 464 LIIRDVKESDQGAYTCEAMNARG 486



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            +I    G  + F C       PT  I W  N   +PS  R   T +    +L I    E 
Sbjct: 415  SIQASRGQTVTFTCVAIGV--PTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 472

Query: 2842 DSGIYTCKATNSKG 2855
            D G YTC+A N++G
Sbjct: 473  DQGAYTCEAMNARG 486



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 20/129 (15%)

Query: 3978 QIQSQTSLV-EMETTKFECQLAPVGDPNMKVEWFFNGK--PLLHKNRFTPIYDFGYVAMN 4034
            +I+S +S V E +T    C +A  G  + +V W+  G   P  H+ R + +Y F      
Sbjct: 2248 RIESSSSTVAEGQTLDLSCVVA--GQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ----- 2300

Query: 4035 FGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASW 4094
                 P D+G+Y+CRA+N  GM E    +  TG  G    + L     S + IR   +S 
Sbjct: 2301 ---ASPADAGQYVCRASN--GM-EASITVTVTGTQG----ANLAYPAGSTQPIRIEPSSS 2350

Query: 4095 QVTPEQVVE 4103
            QV   Q ++
Sbjct: 2351 QVAEGQTLD 2359



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 9/92 (9%)

Query: 3823 EPIVSTPPKFIT---QIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            EP  S P   +T   +I+S + + +EG   +           ++ W++ G  LP+ H+  
Sbjct: 2425 EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVH 2484

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                     L +L V   DSGEY+CR V   G
Sbjct: 2485 GS------RLRLLQVTPADSGEYVCRVVGSSG 2510



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 10/97 (10%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S S P+ ++  S+ P V EG+ + L C +     P   + W+  G S+   SR +T+   
Sbjct: 2627 SVSPPIRIE--SSSPTVVEGQTLDLNCVVARQ--PQAIITWYKRGGSLP--SRHQTHGSH 2680

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
                L +   + AD+GEY  RA N++ +   S ++ V
Sbjct: 2681 ----LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            ++P+ +    +  +++GQ A F + LI    A + +EW   N+ L+     +   +    
Sbjct: 3020 RSPVISIDPPSSTVQQGQDASF-KCLIHDGAAPISLEWKTRNQELEDNVHISPNGSI--- 3075

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             + I+   P + GTY C A NA G A +     VH   ++
Sbjct: 3076 -ITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTV 3114



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 11/124 (8%)

Query: 3826 VSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V +PP + T +  H +V+  E V+ +C       P L  +W R G  LP     R     
Sbjct: 3295 VESPP-YATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARNEL-- 3349

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
                L       EDSG Y CR  N  G     A +  +  P  +    +P G   +  +T
Sbjct: 3350 ----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3405

Query: 3945 -QME 3947
             Q+E
Sbjct: 3406 PQLE 3409



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDP--NLRIEFYHNGKALQSAARFHITFDFG 2298
            PP+ VT  R +     G+T  F C    V  P  N R+ + H    + S  R  +T + G
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGH----IPSHPRVTVTSEGG 460

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALG 2324
              +L I+     D G Y+ +A+NA G
Sbjct: 461  RGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 8/96 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APV ++    +  ++ G+ A F    T +  P L+    W G     G +          
Sbjct: 1865 APVVSIHPPQL-TVQPGQLAEFRCSATGSPTPTLE----WTGGP---GGQLPAKAQIHGG 1916

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            IL +    P D  +YLCRA+++ G+ V  A + V G
Sbjct: 1917 ILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHG 1952



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 9/85 (10%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            S+ P  I    SH V E E +   C V P +    ++ W++ G  LPS H+ R       
Sbjct: 2725 SSMPIRIESSSSH-VAEGETLDLNC-VVPGQ-AHAQVTWHKRGGSLPSHHQTRGS----- 2776

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
              L + +V   DSGEY+CR +   G
Sbjct: 2777 -RLRLHHVSPADSGEYVCRVMGSSG 2800



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 9/87 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            +  R   G  A F     G PTP +SW++           S+  + +  +  L++  + P
Sbjct: 3582 QEVRVPAGSAAVFPCIASGYPTPDISWSKLDG--------SLPPDSRLENNMLMLPSVRP 3633

Query: 139  GDEGEYTCTARNQYGEAICSVYIQ-PE 164
             D G Y CTA N+ G+     ++Q PE
Sbjct: 3634 QDAGTYVCTATNRQGKVKAFAHLQVPE 3660



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP+  T P + I  S   +  F C  I V   +  + W  N   + +  RV   ++ G  
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVAIGV--PTPIINWRLNWGHIPSHPRVTVTSEGGRG 462

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHG 3639
             L I  V + D G YTC+A N  G
Sbjct: 463  TLIIRDVKESDQGAYTCEAMNARG 486



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 9/95 (9%)

Query: 3822 EEPIVSTP-PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            E  ++  P P    +  S TV E + +   C V  +   +  + WY+ G  LP+ H+ R 
Sbjct: 2236 EASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQ--VTWYKRGGSLPARHQVRG 2293

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT 3915
                    L I      D+G+Y+CRA N      T
Sbjct: 2294 ------SRLYIFQASPADAGQYVCRASNGMEASIT 2322



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 244  YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
            YVG   VQ    +  +    +P  +   P  S + +G     + Q+SG+P     W +  
Sbjct: 1657 YVGNPSVQGGQCLPET--NQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSRED 1714

Query: 304  QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESPTESY 362
             R + S   +    H  + L   + Q SD+G Y     N +    +   L V E+P++  
Sbjct: 1715 GRPVPSGTQQ---RHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPI 1771

Query: 363  ---VQDQRSQYI 371
               V++QRSQ +
Sbjct: 1772 TVTVEEQRSQSV 1783



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S   V EGQ +   C +     ++ +V W K G  +   H+   +H      L ++ +  
Sbjct: 2444 SSSQVAEGQTLDLNCLV--AGQAHAQVTWHKRGGSLPARHQ---VHGS---RLRLLQVTP 2495

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRLT 1535
             DSG Y CR V   GT E S  +T
Sbjct: 2496 ADSGEYVCRVVGSSGTQEASVLVT 2519



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            D  DE   + P+ VT P+       GQ V F C    V      + W  N   +    R 
Sbjct: 396  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPI--INWRLNWGHIPSHPRV 453

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
                + G   L I D+   D G YTC A+N  G
Sbjct: 454  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 8/108 (7%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +PP  TT P    +    +   +C  +      +  +W   G  L    R    N+    
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQC--LAHGTPPLTFQWSRVGSSL--PGRATARNE---- 3348

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663
            +L        D+G Y C+ TN+ G A    +L V+G  G +    +P+
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPA 3396



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/70 (25%), Positives = 33/70 (47%), Gaps = 2/70 (2%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           ++G    F     G PTP+++W      +    + ++    + G  +L+I+ +   D+G 
Sbjct: 419 SRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTV--TSEGGRGTLIIRDVKESDQGA 476

Query: 144 YTCTARNQYG 153
           YTC A N  G
Sbjct: 477 YTCEAMNARG 486



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+   +R +T+     
Sbjct: 2151 TRPIRIEPSSSH--VAEGQTLDLNCVVP--GQAHAQVTWHKRGGSLP--ARHQTHGSL-- 2202

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +   T AD+GEY    V   G    S +V +
Sbjct: 2203 --LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P +I    SH V E + +   C V P +    ++ WY+ G  LP+ H+           L
Sbjct: 2926 PIYIEASSSH-VTEGQTLDLNC-VVPGQ-AHAQVTWYKRGGSLPARHQTHGS------QL 2976

Query: 3890 DILYVYAEDSGEYICRAVNDFGED 3913
             +  V   DSGEY+CRA +  G +
Sbjct: 2977 RLHLVSPADSGEYVCRAASGPGPE 3000



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 25/55 (45%)

Query: 4090 MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            M A  Q T    V+ S     PV    P  +TV+ G+ A F C  TG P P + W
Sbjct: 1845 MFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1899



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S + P  V+  S+ P V+EG+ + L C +   G    +V W+  G S+   ++       
Sbjct: 2046 SDASPPPVKIESSSPSVTEGQTLDLNCVVA--GSAHAQVTWYRRGGSLPPHTQVHGS--- 2100

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
                L +   + AD+GEY  R  N  G    S  V V+
Sbjct: 2101 ---RLRLPQVSPADSGEYVCRVENGSGPKEASITVSVL 2135



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+ V  R +T+     
Sbjct: 2340 TQPIRIEPSSSQ--VAEGQTLDLNCVVP--GQSHAQVTWHKRGGSLPV--RHQTHGSL-- 2391

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +  A+ AD+GEY  R +        S +V +
Sbjct: 2392 --LRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2424



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 8/96 (8%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P   +   S T +EG  +     +     P   I W K G S+ +  +        ++ L
Sbjct: 2630 PPIRIESSSPTVVEGQTLDLNCVV--ARQPQAIITWYKRGGSLPSRHQTHG----SHLRL 2683

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
              +S  + DSGEY CRA +     E   V+ V+P A
Sbjct: 2684 HQMS--VADSGEYVCRANNNIDALEASIVISVSPSA 2717



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 3695 PRFTVEIKDNID-VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P   + I+ ++  V  G  V F+C    +GDP  ++ W   G     G     +   G +
Sbjct: 3487 PSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVV 3540

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL--ESQLPQG 3802
               I ++   DAG+Y C ATN  G+  +   +   A   I +  E ++P G
Sbjct: 3541 R--IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAG 3589



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 10/123 (8%)

Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVAL 2169
            V +   TS++ +  G    FEC    + DP   + W   G  +R G         G V  
Sbjct: 3489 VLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVVR- 3541

Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL--DTQHPNGLEKIRQLEAQG 2227
             I +    D+G Y C ATN  G   +   L V     I +  + + P G   +    A G
Sbjct: 3542 -IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCIASG 3600

Query: 2228 HST 2230
            + T
Sbjct: 3601 YPT 3603



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 12/80 (15%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP--IHDFGYVALDIIDL 1509
            S++ V+ G  V FEC    + D   +V W K G     GH  RP  +   G V +  ++L
Sbjct: 3496 SVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GH-LRPGIVQSGGVVRIAHVEL 3547

Query: 1510 IAEDSGIYTCRAVNLVGTDE 1529
               D+G Y C A N  GT +
Sbjct: 3548 A--DAGQYRCTATNAAGTTQ 3565



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 9/100 (9%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++   P  +MP +++RV    AA F    I  G P   + W +    +   +RL      
Sbjct: 3571 LVQALPQISMP-QEVRVPAGSAAVFPC--IASGYPTPDISWSKLDGSLPPDSRLENN--- 3624

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                L +  V P+D+GTY C A N  G+    + L V  +
Sbjct: 3625 ---MLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3661


>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
            perlecan protein.
          Length = 4370

 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 104/424 (24%), Positives = 174/424 (41%), Gaps = 48/424 (11%)

Query: 4394 AQTQERVV--EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI 4451
            AQ Q  V+   G + P  P +  ++ +   V     A       G P P I W +   P+
Sbjct: 3173 AQKQVEVIVDTGAMAPGAPQVQAEEAE-LTVEAGHTATLRCSATGSPAPTIHWSKLRSPL 3231

Query: 4452 KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGI 4511
                  +  T      LII +V  +DS  +   A +  G A+ +  L VE          
Sbjct: 3232 PWQHRLEGDT------LIIPRVAQQDSGQYICNATSPAGHAEATIILHVES--------- 3276

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
             PP  T   ++ +V +G+ V+L     GT P+   W + G  +  +   RN++L  +   
Sbjct: 3277 -PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFE--- 3332

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP- 4628
                  A P+DSG+Y C   N  G A   A+ +V  P     P     A + P   + P 
Sbjct: 3333 -----RAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP-PGSLPATSIPAGSTPTVQVTPQ 3386

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L+ K +  G ++EF C +       ++W+K    + P        +  +  LRI      
Sbjct: 3387 LETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP------GHSVQDGVLRIQNLDQS 3438

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             +G Y C A+   G+   +A+L V Q   +  +   T ++ +VV  G   +F+       
Sbjct: 3439 CQGTYICQAHGPWGKAQASAQL-VIQALPSVLINIRTSVQTVVV--GHAVEFECLALGDP 3495

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            KP + W + G  +   P   ++  G   V+ I +    D G + C AT AAG  ++   L
Sbjct: 3496 KPQVTWSKVGGHL--RPG--IVQSG--GVVRIAHVELADAGQYRCTATNAAGTTQSHVLL 3549

Query: 4809 VVKS 4812
            +V++
Sbjct: 3550 LVQA 3553



 Score = 94.7 bits (225), Expect = 7e-18
 Identities = 106/422 (25%), Positives = 164/422 (38%), Gaps = 57/422 (13%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQI 4459
            +  PV    PP  T  +QP ++     A F     G P P ++W     P    P   QI
Sbjct: 1842 LSAPVVSIHPPQLT--VQPGQL-----AEFRCSATGSPTPTLEW--TGGPGGQLPAKAQI 1892

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            H      IL +  V   D A +   A +  G     A L V      G GG   P   ++
Sbjct: 1893 HG----GILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVH-----GGGG---PRVQVS 1940

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             +   V +G+ VRL  +  G     + W K G  + P  R+   E     TLLI      
Sbjct: 1941 PERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARS---ERTDIATLLIPAITTA 1997

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y CVA + AG A+   + VV L A+   P P    +++P           V EGQ 
Sbjct: 1998 DAGFYLCVATSPAGTAQARIQVVV-LSASDASPPPVKIESSSPS----------VTEGQT 2046

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            ++ +C + G     V WY+    + P      SR      LR+ +  P D G+Y C   N
Sbjct: 2047 LDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSR------LRLPQVSPADSGEYVCRVEN 2100

Query: 4700 SAG----RVTVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKP 4750
             +G     +TV+             +P  T P+R       V EGQ       +  +   
Sbjct: 2101 GSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHA 2160

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             + W + G  +P        H+ + ++L +      D+G + C     +G +E S  + +
Sbjct: 2161 QVTWHKRGGSLPAR------HQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2214

Query: 4811 KS 4812
            ++
Sbjct: 2215 EA 2216



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 100/412 (24%), Positives = 148/412 (35%), Gaps = 43/412 (10%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIH 4460
            EG     + P+ +       V + + A F+        P+ ++W   N  ++++    +H
Sbjct: 2992 EGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VH 3047

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                 SI+ I      +   +  VA N  G A+   NL V            PP+ ++  
Sbjct: 3048 ISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG----------PPTVSVLP 3097

Query: 4521 QN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            +  V V  G+ V L+    G       W +         +      D    L I  A P 
Sbjct: 3098 EGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPS 3157

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y C+A N+ G A+   E +V   A      PQ +A  A         +  V  G  
Sbjct: 3158 DAGTYVCLAQNALGTAQKQVEVIVDTGAMA-PGAPQVQAEEA---------ELTVEAGHT 3207

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
                C   G P PT+ W    KL  P  + Q     D  TL I     +D G Y C A +
Sbjct: 3208 ATLRCSATGSPAPTIHW---SKLRSPLPW-QHRLEGD--TLIIPRVAQQDSGQYICNATS 3261

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
             AG       L V  P  A  +P         V  G+  Q +         T QW R G+
Sbjct: 3262 PAGHAEATIILHVESPPYATTVP-----EHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 3316

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P            N +L       ED+G + CR T   G  E  A+L+V+
Sbjct: 3317 SLPGRA------TARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQ 3362



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 77/353 (21%), Positives = 148/353 (41%), Gaps = 32/353 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L + QV   DS  +        GT + S  + ++++        V     + + + ++
Sbjct: 2465 SRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASL 2524

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             +G  + L+  V    P  + W K G  +    R++I+       L I +  P DSG+Y 
Sbjct: 2525 ANGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGS----RLRIPQVTPADSGEYV 2578

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C   N AG    +   +V++  +     P      +PP  IE     +V EGQ ++ +C 
Sbjct: 2579 CHVSNGAGSR--ETSLIVTIQGSGSSHVPSV----SPPIRIESSSPTVV-EGQTLDLNCV 2631

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            +  +P   + WYK G  L  PS++    +T   + LR+ +    D G+Y C A N+   +
Sbjct: 2632 VARQPQAIITWYKRGGSL--PSRH----QTHGSH-LRLHQMSVADSGEYVCRANNNIDAL 2684

Query: 4705 TVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + V+    + + P  + P+R       V EG+       +  +    + W + G 
Sbjct: 2685 EASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG 2744

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +P        H+   + L + +    D+G + CR   ++G +E S  + +++
Sbjct: 2745 SLPSH------HQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEA 2791



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 90/356 (25%), Positives = 148/356 (41%), Gaps = 41/356 (11%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S+L + QV   DS  +        G  + S  + +E     G    +PP   + + +  V
Sbjct: 2180 SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGP---IPP-VRIESSSSTV 2235

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L   V G     V W K G  +    R+++        L I +A P D+G+Y 
Sbjct: 2236 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA--RHQVRGS----RLYIFQASPADAGQYV 2289

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N       +A   V++  T+        A +  P  IEP   + VAEGQ ++ +C 
Sbjct: 2290 CRASNGM-----EASITVTVTGTQGANLAYP-AGSTQPIRIEPSSSQ-VAEGQTLDLNCV 2342

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            + G+    V W+K G  L  P ++           LR+ +A P D G+Y C    S+  V
Sbjct: 2343 VPGQSHAQVTWHKRGGSL--PVRH-----QTHGSLLRLYQASPADSGEYVCRVLGSS--V 2393

Query: 4705 TVAAKLKVTQPDQADNLPAL--TPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWLRE 4757
             + A + VT  + A ++PAL  TP   I      V EGQ       +  +    + W + 
Sbjct: 2394 PLEASVLVTI-EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKR 2452

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            G  +P        H+ + + L +      D+G + CR   ++G  E S  + ++ +
Sbjct: 2453 GGSLPAR------HQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2502



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 100/413 (24%), Positives = 162/413 (39%), Gaps = 45/413 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            S PP+  +   P  V E +         G     + WYR    +   P  Q+H     S 
Sbjct: 2028 SPPPVKIESSSPS-VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLP--PHTQVHG----SR 2080

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT----LTAQNV 4523
            L + QV   DS  +    EN  G  + S  + V      G      P  T    +   + 
Sbjct: 2081 LRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSS 2140

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            +V  GQ + L+  V G     V W K G  +    R+   +  G+  L + +  P DSG+
Sbjct: 2141 HVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RH---QTHGSL-LRLHQVTPADSGE 2194

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C  + ++G    +A  +V++ A+   P P       PP  IE      VAEGQ ++ S
Sbjct: 2195 YVCHVVGTSGPL--EASVLVTIEASVI-PGP------IPPVRIES-SSSTVAEGQTLDLS 2244

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C + G+    V WYK    +      + SR      L I +A P D G Y C A N    
Sbjct: 2245 CVVAGQAHAQVTWYKRGGSLPARHQVRGSR------LYIFQASPADAGQYVCRASNGM-E 2297

Query: 4704 VTVAAKLKVTQ-PDQADNLPALTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
             ++   +  TQ  + A    +  P+R       V EGQ       +  +    + W + G
Sbjct: 2298 ASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG 2357

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              +P      + H+ + ++L +      D+G + CR   ++  +E S  + ++
Sbjct: 2358 GSLP------VRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE 2404



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 95/410 (23%), Positives = 160/410 (39%), Gaps = 52/410 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP  T   +   V   E  + +    G P    +W R    +           +   +L 
Sbjct: 3277 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPG------RATARNELLH 3330

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP----PSFTLTAQNVNV 4525
              +   EDS  +     N+ G+A+  A L+V+          +P    P+  +T Q    
Sbjct: 3331 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3390

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            + G  V     V   +   + W K G ++ P   + +  +DG   +  L+   Q  G Y 
Sbjct: 3391 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPG--HSV--QDGVLRIQNLDQSCQ--GTYI 3444

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI--VAEGQAIEFS 4643
            C A    G+A+  A+ V+                 A P ++  ++  +  V  G A+EF 
Sbjct: 3445 CQAHGPWGKAQASAQLVIQ----------------ALPSVLINIRTSVQTVVVGHAVEFE 3488

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C  +G P P V W K    ++P              +RI+     D G Y+C A N+AG 
Sbjct: 3489 CLALGDPKPQVTWSKVGGHLRP------GIVQSGGVVRIAHVELADAGQYRCTATNAAG- 3541

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             T +  L + Q      LP ++  +++ V  G  A F    +    P I W +    +P 
Sbjct: 3542 TTQSHVLLLVQA-----LPQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLP- 3595

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             PD ++     N +L++ +   +D GT+ C AT   G+V+  A L V  +
Sbjct: 3596 -PDSRL----ENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3640



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 74/305 (24%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V P+  + + +  V  GQ + L+  V G     V W K G  +    R+++    G+  L
Sbjct: 2414 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV---HGS-RL 2467

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             +L+  P DSG+Y C  + S+G    +A  +V++   + +         A P  IE    
Sbjct: 2468 RLLQVTPADSGEYVCRVVGSSGTQ--EASVLVTI---QQRLSGSHSQGVAYPVRIES-SS 2521

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
              +A G  ++ +C +  +   T+ WYK G  L  PS++  +        LRI +  P D 
Sbjct: 2522 ASLANGHTLDLNCLVASQAPHTITWYKRGGSL--PSRHQIVGS-----RLRIPQVTPADS 2574

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQIT 4745
            G+Y C   N AG    +  + + Q   + ++P+++P   I      V EGQ       + 
Sbjct: 2575 GEYVCHVSNGAGSRETSLIVTI-QGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 2633

Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             + +  I W + G  +P        H+ + + L +      D+G + CRA      +E S
Sbjct: 2634 RQPQAIITWYKRGGSLPSR------HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEAS 2687

Query: 4806 AKLVV 4810
              + V
Sbjct: 2688 IVISV 2692



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 79/354 (22%), Positives = 146/354 (41%), Gaps = 33/354 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L I QV   DS  +     N  G+ + S  + ++         + PP   + + +  V
Sbjct: 2562 SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPP-IRIESSSPTV 2620

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L+  V       + W K G  +    R+   +  G++ L + +    DSG+Y 
Sbjct: 2621 VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RH---QTHGSH-LRLHQMSVADSGEYV 2674

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N+      +A  V+S+  +   P   +   ++ P  IE      VAEG+ ++ +C 
Sbjct: 2675 CRANNNIDAL--EASIVISVSPSAGSP---SAPGSSMPIRIESSSSH-VAEGETLDLNCV 2728

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            + G+    V W+K    +      + SR      LR+    P D G+Y C    S+G + 
Sbjct: 2729 VPGQAHAQVTWHKRGGSLPSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLE 2782

Query: 4706 VAAKLKV-TQPDQADNLPA---LTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
             +  + +      A ++PA     P+R       V EGQ    K  +  +    + W + 
Sbjct: 2783 ASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKR 2842

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G  +P        H+ +  +L +      D+G ++C+ T ++G +E S  + ++
Sbjct: 2843 GGNLPAR------HQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIE 2890



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 87/362 (24%), Positives = 140/362 (38%), Gaps = 34/362 (9%)

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP---PSF 4516
            H  +  S L +  V   DS  +        G  + S  + +E           P   P  
Sbjct: 2749 HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPI 2808

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
             +   +  V  GQ + L   V G     V W K G  +    R+++    G   L + + 
Sbjct: 2809 RIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPA--RHQV---HGPL-LRLNQV 2862

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
             P DSG+Y C    S+G    +A  +V++  +   P P    A   P  IE      V E
Sbjct: 2863 SPADSGEYSCQVTGSSGTL--EASVLVTIEPSSPGPIPAPGLAQ--PIYIEASSSH-VTE 2917

Query: 4637 GQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            GQ ++ +C + G+    V WYK G  L  P+++           LR+    P D G+Y C
Sbjct: 2918 GQTLDLNCVVPGQAHAQVTWYKRGGSL--PARH-----QTHGSQLRLHLVSPADSGEYVC 2970

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQITSKIKP 4750
             A +  G    A+      P +  +    +P+  I      V +GQ A FK  I     P
Sbjct: 2971 RAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAP 3030

Query: 4751 -TIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +++W      + +      +H   N +++ I  T   + GT+ C A+ A G  ++   L
Sbjct: 3031 ISLEWKTRNQELEDN-----VHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNL 3085

Query: 4809 VV 4810
             V
Sbjct: 3086 SV 3087



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 30/292 (10%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V  GQ + L+  V G     V W K G  +   +R+   +  G+  L + +A P DSG+Y
Sbjct: 2331 VAEGQTLDLNCVVPGQSHAQVTWHKRGGSLP--VRH---QTHGSL-LRLYQASPADSGEY 2384

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C  + S+     +A  +V++     +P     A    P +        VAEGQ ++ +C
Sbjct: 2385 VCRVLGSS--VPLEASVLVTI-----EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNC 2437

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             + G+    V W+K    +        SR      LR+ +  P D G+Y C    S+G  
Sbjct: 2438 LVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSGEYVCRVVGSSGTQ 2491

Query: 4705 TVAAKLKVTQ-----PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + + Q       Q    P         +  G        + S+   TI W + G 
Sbjct: 2492 EASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGG 2551

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P        H+   + L I      D+G + C  +  AG  ETS  + ++
Sbjct: 2552 SLPSR------HQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2597



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 103/486 (21%), Positives = 168/486 (34%), Gaps = 54/486 (11%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A+F     G+PTP + WT      +           Q     L +  + P D+ +Y 
Sbjct: 1859 GQLAEFRCSATGSPTPTLEWTGGPGGQLPAKA-------QIHGGILRLPAVEPTDQAQYL 1911

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH--KAYGTQGYTTEQSRQ 203
            C A +  G+ +    +   G               H   TV    +A G    T    ++
Sbjct: 1912 CRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE 1971

Query: 204  TQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
               +     ++ +      +         +  F   +     G +  +I   +  S    
Sbjct: 1972 GGSLPPQARSERTDIATLLIPAIT---TADAGFYLCVATSPAGTAQARIQVVV-LSASDA 2027

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP +  +  +  + EG        ++G+   +VTW++ G  L     H   T  + + L
Sbjct: 2028 SPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSL---PPH---TQVHGSRL 2081

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            R+     +DSG Y    EN +G    S  ++V   T S          T         RI
Sbjct: 2082 RLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHS------GPSYTPVPGSTRPIRI 2135

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            E S                V EG+    +C V G+ + +VTW      +   +       
Sbjct: 2136 EPSSS-------------HVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARH------- 2175

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--STLN 501
            ++    L +  VT +DSG   C     SG       L  IE   +  P    R   S+  
Sbjct: 2176 QTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSST 2234

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + L+    G    ++TW K G  +    ++R       S L I +A  +DA  Y
Sbjct: 2235 VAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVR------GSRLYIFQASPADAGQY 2288

Query: 562  QCTAQN 567
             C A N
Sbjct: 2289 VCRASN 2294



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 56/177 (31%), Positives = 74/177 (41%), Gaps = 21/177 (11%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G    F+C   G P P+VTW      +R       +V   G   + I +V L+D+G 
Sbjct: 3479 VVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG-----IVQSGG--VVRIAHVELADAGQ 3531

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A N +G T     L V    Q+  P+ V       V  G   V    A G PTP I
Sbjct: 3532 YRCTATNAAGTTQSHVLLLVQALPQISMPQEV------RVPAGSAAVFPCIASGYPTPDI 3585

Query: 523  TWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +W K DG   +P P+ R+      + L +P  +  DA  Y CTA N  G     A L
Sbjct: 3586 SWSKLDG--SLP-PDSRLEN----NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHL 3635



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 45/177 (25%), Positives = 77/177 (43%), Gaps = 11/177 (6%)

Query: 395  VKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            V+V  +R  V  G+  R  CR  G P   +TW    R+       +     +    L+I 
Sbjct: 1937 VQVSPERTQVHAGRTVRLYCRAAGVPSATITW----RKEGGSLPPQARSERTDIATLLIP 1992

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
             +T +D+G   CVA + +G    + ++ V+       P      S+ +V EG+ + LN  
Sbjct: 1993 AITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCV 2052

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G+   ++TW + G  + P      HT    S L +P+   +D+  Y C  +N +G
Sbjct: 2053 VAGSAHAQVTWYRRGGSLPP------HTQVHGSRLRLPQVSPADSGEYVCRVENGSG 2103



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 112/531 (21%), Positives = 179/531 (33%), Gaps = 67/531 (12%)

Query: 52   VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
            +E+SG    +    PG   P   E    ++R A+G     +  + G     V+W ++   
Sbjct: 2789 IEASGS-SAVHVPAPGGAPPIRIEP--SSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGN 2845

Query: 112  LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXX 171
            L            Q     L + Q+ P D GEY+C      G    SV +  E       
Sbjct: 2846 LPA--------RHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPI 2897

Query: 172  XXXXXXXYRHVSETVEHKAYGTQ---GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEY 228
                     ++  +  H   G               Q   Y  G    +           
Sbjct: 2898 PAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRL 2957

Query: 229  RLLREVSFRESITKRYVG---ESDVQISTEIDRSLGP---VSPPKIAQKPRNSKLQEGAD 282
             L+      E + +   G   E +   +  +  S G    +  P I+  P +S +Q+G D
Sbjct: 2958 HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQD 3017

Query: 283  AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            A F+  +     P    +K   + +  N H    + N + + +  T+ S+ G Y      
Sbjct: 3018 ASFKCLIHDGAAPISLEWKTRNQELEDNVH---ISPNGSIITIVGTRPSNHGTYR----- 3069

Query: 343  PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
               C+ ++ Y   +S     V    +                +S     P +VKV     
Sbjct: 3070 ---CVASNAYGVAQSVVNLSVHGPPT----------------VSVLPEGPVWVKV----- 3105

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHA-LMITNVTLSDS 460
               GK    +C   G P     W  I+    + +     L++   +HA L I++   SD+
Sbjct: 3106 ---GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMD---SHAVLQISSAKPSDA 3159

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
            G   C+A+N  G    Q  + V        AP+     + L V  G    L   A G+P 
Sbjct: 3160 GTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPA 3219

Query: 520  PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P I W K   P+     L         TL IPR    D+  Y C A + AG
Sbjct: 3220 PTIHWSKLRSPLPWQHRLE------GDTLIIPRVAQQDSGQYICNATSPAG 3264



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 80/315 (25%), Positives = 109/315 (34%), Gaps = 41/315 (13%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP     P ++ +Q G   Q Q    G P     W + G  L          T  +  L
Sbjct: 3276 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGR------ATARNELL 3329

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG Y     N  G       L V+ P  S          T T Q       
Sbjct: 3330 HFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ------- 3382

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
                  + PQ     + + +  G    F C V      ++ WF    Q+     H +   
Sbjct: 3383 ------VTPQL----ETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP--GHSV--- 3425

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            + G   L I N+  S  G   C A    G+     +L VI+    V      R S   V 
Sbjct: 3426 QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQASAQL-VIQALPSVLINI--RTSVQTVV 3480

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             G  V     A+G P P++TW K G  + P     I   GG   + I   + +DA  Y+C
Sbjct: 3481 VGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGG--VVRIAHVELADAGQYRC 3534

Query: 564  TAQNVAGSTATRARL 578
            TA N AG+T +   L
Sbjct: 3535 TATNAAGTTQSHVLL 3549



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 115/528 (21%), Positives = 187/528 (35%), Gaps = 68/528 (12%)

Query: 62   TAGRPGEPSPPIFEQI-FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            +AG P  P   +  +I   ++  A+G        + G     V+W ++          S+
Sbjct: 2695 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG--------SL 2746

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXX 178
              + QT    L +  + P D GEY C      G  EA   V I+  G             
Sbjct: 2747 PSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAP 2806

Query: 179  YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV-DTFEYRLLR--EVS 235
               +  +    A   +G T +        A+   T H    +          LLR  +VS
Sbjct: 2807 PIRIEPSSSRVA---EGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVS 2863

Query: 236  FRES--ITKRYVGES---DVQISTEIDRSL-GPVSPPKIAQ----KPRNSKLQEGADAQF 285
              +S   + +  G S   +  +   I+ S  GP+  P +AQ    +  +S + EG     
Sbjct: 2864 PADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2923

Query: 286  QVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               + G    +VTW+K G  L    +H+   TH  + LR+     +DSG Y   A +  G
Sbjct: 2924 NCVVPGQAHAQVTWYKRGGSL--PARHQ---THG-SQLRLHLVSPADSGEYVCRAASGPG 2977

Query: 346  CIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTE 405
                + +     P+E      RS  I+      T                       V +
Sbjct: 2978 PEQEASFTVTVPPSEGSSYRLRSPVISIDPPSST-----------------------VQQ 3014

Query: 406  GKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
            G+   F C +     P  + W   ++++ D+ +    ++ +G+  + I     S+ G   
Sbjct: 3015 GQDASFKCLIHDGAAPISLEWKTRNQELEDNVH----ISPNGS-IITIVGTRPSNHGTYR 3069

Query: 465  CVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
            CVA N  G       L+V     V V P+       + V+ G+ V L   + G P     
Sbjct: 3070 CVASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVWVKVGKAVTLECVSAGEPRSSAR 3124

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            W +         +         + L I  AK SDA  Y C AQN  G+
Sbjct: 3125 WTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGT 3172



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 5/133 (3%)

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            N  L I NV LSD+G   C   N          L+V     + AP        L V+ G+
Sbjct: 1801 NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQ 1860

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
                   A G+PTP + W       +P  + +IH  GG   L +P  + +D A Y C A 
Sbjct: 1861 LAEFRCSATGSPTPTLEWTGGPGGQLP-AKAQIH--GG--ILRLPAVEPTDQAQYLCRAH 1915

Query: 567  NVAGSTATRARLY 579
            + AG    RA L+
Sbjct: 1916 SSAGQQVARAVLH 1928



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 12/176 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G++  F C  TG P P + W             K  ++      L +  V  +D   
Sbjct: 1856 VQPGQLAEFRCSATGSPTPTLEWTGGPG---GQLPAKAQIHGG---ILRLPAVEPTDQAQ 1909

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A + +G+   +  L+V        P+         V  G  V L  RA G P+  I
Sbjct: 1910 YLCRAHSSAGQQVARAVLHV---HGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATI 1966

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            TW+K+G  + P       TD   +TL IP    +DA +Y C A + AG+   R ++
Sbjct: 1967 TWRKEGGSLPPQARSE-RTD--IATLLIPAITTADAGFYLCVATSPAGTAQARIQV 2019



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 53/231 (22%), Positives = 82/231 (35%), Gaps = 20/231 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H++          L +L     DSG
Sbjct: 2427 VAEGQTL--DLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSG 2478

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CR     G  E SV +    +  G   +   +   IE     L +G +    C V  
Sbjct: 2479 EYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVA- 2537

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
                   I WY  G  +   +R + V       L I      DSGEYVC   N  G   T
Sbjct: 2538 -SQAPHTITWYKRGGSL--PSRHQIVGSR----LRIPQVTPADSGEYVCHVSNGAGSRET 2590

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
               +   G G  ++ S+ P    +      ++G         + +P   IT
Sbjct: 2591 SLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIIT 2641



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 14/173 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + +GQ A ++  LI  G   + +EW    + +E +  I    +    ++ I+GT+ ++ G
Sbjct: 3012 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHG 3066

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
            TY C A+N +G A+  V L     S    P  +   +    +K G++   EC  V   +P
Sbjct: 3067 TYRCVASNAYGVAQSVVNL-----SVHGPPTVSVLPEGPVWVKVGKAVTLEC--VSAGEP 3119

Query: 3180 DMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                 W   +  P +   R   + D    VL I+  +  D+G YVC A N  G
Sbjct: 3120 RSSARWTRISSTPAKLEQRTYGLMD-SHAVLQISSAKPSDAGTYVCLAQNALG 3171



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 8/140 (5%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I   + +D+GTY C  +N +   + +  L          P  + H   +  ++ GQ 
Sbjct: 1803 ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT-VQPGQL 1861

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A F C+      P   +EW   G P     ++   +     +L +   +  D  +Y+CRA
Sbjct: 1862 AEFRCSAT--GSPTPTLEW--TGGP---GGQLPAKAQIHGGILRLPAVEPTDQAQYLCRA 1914

Query: 3227 YNKYGEDFTRATINCYGKGG 3246
            ++  G+   RA ++ +G GG
Sbjct: 1915 HSSAGQQVARAVLHVHGGGG 1934



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 80/320 (25%), Positives = 123/320 (38%), Gaps = 52/320 (16%)

Query: 261  GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
            G   P +I  +P +S++ EG        + G    +VTW K G  L    +H+   TH  
Sbjct: 2317 GSTQPIRI--EPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSL--PVRHQ---THG- 2368

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
            + LR+     +DSG Y       +  +  S  + +E P  S      +  +T T      
Sbjct: 2369 SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVP----ALGVTPTV----- 2418

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
             RIE S   +A             EG+    +C V G+ + +VTW      +     H++
Sbjct: 2419 -RIESSSSQVA-------------EGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV 2462

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGE------TAFQCRLNVIEKEQVVAPKFV 494
                 G+  L +  VT +DSG   C     SG          Q RL+    + V  P  +
Sbjct: 2463 ----HGSR-LRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRI 2517

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
            E  S+ ++  G  + LN          ITW K G  +    ++        S L IP+  
Sbjct: 2518 ES-SSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI------VGSRLRIPQVT 2570

Query: 555  ASDAAWYQCTAQNVAGSTAT 574
             +D+  Y C   N AGS  T
Sbjct: 2571 PADSGEYVCHVSNGAGSRET 2590



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 11/125 (8%)

Query: 4583 KYECVAINSAGEA--RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQA 4639
            ++ CV+ N    A   CD E         D P    +    PP+++ P ++ I A  GQ 
Sbjct: 351  QFRCVSTNMCIPASFHCDEE--------SDCPDRSDEFGCMPPQVVTPPRESIQASRGQT 402

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            + F+C  +G P P + W      I       ++      TL I +    D+G Y C A N
Sbjct: 403  VTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMN 462

Query: 4700 SAGRV 4704
            + G V
Sbjct: 463  ARGMV 467



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 24/72 (33%), Positives = 35/72 (48%)

Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           ++    G+ V     A+G PTP I W+ +   I  +P + + ++GG  TL I   K SD 
Sbjct: 394 SIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQ 453

Query: 559 AWYQCTAQNVAG 570
             Y C A N  G
Sbjct: 454 GAYTCEAMNARG 465



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 60/246 (24%), Positives = 95/246 (38%), Gaps = 42/246 (17%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E TI     +PP +   + ++  V  G  V   C     G P +   W   G       R
Sbjct: 3267 EATIILHVESPP-YATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLP--GR 3321

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
                N+     L  +     D+G Y CR TNK GSA   A++        +  + +P G 
Sbjct: 3322 ATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGS 3377

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            +                   P V   P    Q+++ ++  S  V F C V      +LR 
Sbjct: 3378 T-------------------PTVQVTP----QLETKSIGAS--VEFHCAVPSDRGTQLR- 3411

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             W++ G  LP GH   +V D G + +  L    +  G YIC+A   +G+    A +  + 
Sbjct: 3412 -WFKEGGQLPPGH---SVQD-GVLRIQNLDQSCQ--GTYICQAHGPWGKAQASAQLVIQA 3464

Query: 3924 LPDIIL 3929
            LP +++
Sbjct: 3465 LPSVLI 3470



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 2377 VFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSM 2436
            V T P ++I     GQT  F C  + +G PT  + W  N   I    R+T T + G  ++
Sbjct: 387  VVTPPRESIQ-ASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 443

Query: 2437 TISHVRDEDEGVYMCRASNLLG 2458
             I  V++ D+G Y C A N  G
Sbjct: 444  IIRDVKESDQGAYTCEAMNARG 465



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 58/278 (20%), Positives = 105/278 (37%), Gaps = 24/278 (8%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A       G+P P + W++ ++PL   ++         GD +L+I ++   D G+Y 
Sbjct: 3205 GHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLE-------GD-TLIIPRVAQQDSGQYI 3256

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQ 205
            C A +  G A  ++ +  E                  +  ++  A+GT   T + SR   
Sbjct: 3257 CNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 3316

Query: 206  KVAYTNGTDHSSTDDFK----VDTFEY--RLLREVSFRESITKRYVGESDVQISTEIDRS 259
             +     T  +    F+     D+  Y  R+  +V   E+  +  V      +      S
Sbjct: 3317 SLP-GRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPA---TS 3372

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            +   S P +   P+      GA  +F   +  +   ++ WFK G +L     H +     
Sbjct: 3373 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQL--PPGHSV----Q 3426

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
               LR++N  +S  G Y   A  P G    S  L +++
Sbjct: 3427 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQA 3464



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 18/155 (11%)

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
            D+   + WF  G  +   H ++        VL I     +  GTY C+A   WG+A+ S 
Sbjct: 3405 DRGTQLRWFKEGGQLPPGHSVQDG------VLRIQNLDQSCQGTYICQAHGPWGKAQASA 3458

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +L  +           T +Q +     G +  FEC  + + DP  ++ W   G  +R   
Sbjct: 3459 QL-VIQALPSVLINIRTSVQTV---VVGHAVEFEC--LALGDPKPQVTWSKVGGHLRPG- 3511

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                V   G  V+ IA+ +  D+G+Y C A N  G
Sbjct: 3512 ---IVQSGG--VVRIAHVELADAGQYRCTATNAAG 3541



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 56/240 (23%), Positives = 91/240 (37%), Gaps = 44/240 (18%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            ++P +   +    +++ GE    +     T  P L  +W   G SL   +  R       
Sbjct: 3275 ESPPYATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARN------ 3326

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537
             +L      PEDSG Y CR  N  G A   A + VQG    +  + +P G   T+     
Sbjct: 3327 ELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ---- 3382

Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
                      +TP+ E+               S  +S  F C  +P +D   ++ WF  G
Sbjct: 3383 ----------VTPQLET--------------KSIGASVEFHC-AVP-SDRGTQLRWFKEG 3416

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
              L  G  V+        +L I  + Q   G Y C+A    G+A  S +L ++    +++
Sbjct: 3417 GQLPPGHSVQD------GVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLI 3470



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + S +  G     + W+  G ++ A H++R    +      I      D+G
Sbjct: 2235 VAEGQTL--DLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLY------IFQASPADAG 2286

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CRA+N   +A I+V +     +    P  +T    IE     + +GQ+    C VVP
Sbjct: 2287 QYVCRASNGM-EASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC-VVP 2344

Query: 3176 VDDPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                  ++ W+  G   P+RH T           +L +      DSGEYVCR
Sbjct: 2345 -GQSHAQVTWHKRGGSLPVRHQTHGS--------LLRLYQASPADSGEYVCR 2387



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 59/239 (24%), Positives = 87/239 (36%), Gaps = 19/239 (7%)

Query: 4581 SGKYECVAINSAGEARCDAEC---VVSLPATKD-KPKPQTKAANAPPEIIEPLKDKIVAE 4636
            +G Y C A       +   +C    V  P+ +  +  P+T  A    E+  P +  IV +
Sbjct: 1612 AGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEV-HPARS-IVPQ 1669

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G +    C++ G P     W + D    PS   Q  + ++   L      P D G Y C 
Sbjct: 1670 GGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSE---LHFPSVQPSDAGVYICT 1726

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP-TIQWL 4755
              N     T  A+L VT+         +   R   V  G    F     SK    T+ W 
Sbjct: 1727 CRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWT 1786

Query: 4756 R--EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            R   G L     DF       N +L I N    D GT+ C  +      + +A L V++
Sbjct: 1787 RLHNGKLPTRAMDF-------NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQA 1838



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 25/181 (13%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    +  ++P G     + W   G  + A H++         +L +      DSG
Sbjct: 2817 VAEGQTLDLKC-VVP-GQAHAQVTWHKRGGNLPARHQVHGP------LLRLNQVSPADSG 2868

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKP----RFTTHIQ-NIEGLKDGQSAHFECTVV 3174
             YSC+ T   G  E SV +     S G  P        +I+ +   + +GQ+    C VV
Sbjct: 2869 EYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VV 2927

Query: 3175 PVDDPDMKIEWYHNG--QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P      ++ WY  G   P RH T            L +      DSGEYVCRA +  G 
Sbjct: 2928 P-GQAHAQVTWYKRGGSLPARHQTHGSQ--------LRLHLVSPADSGEYVCRAASGPGP 2978

Query: 3233 D 3233
            +
Sbjct: 2979 E 2979



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 6/116 (5%)

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADN---LP--ALTPLRD-IVVYEGQPAQFKTQITS 4746
            ++CV+ N     +     +   PD++D    +P   +TP R+ I    GQ   F      
Sbjct: 352  FRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIG 411

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
               P I W      IP  P   +  EG    L+I +  E D G +TC A  A G V
Sbjct: 412  VPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMV 467



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 17/188 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W+  G ++ A H+           L +      DSG
Sbjct: 2915 VTEGQTL--DLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQ------LRLHLVSPADSG 2966

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE----GLKDGQSAHFECTVVP 3175
             Y CRA +  G  + +     V  S+G   R  + + +I+     ++ GQ A F+C +  
Sbjct: 2967 EYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHD 3026

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               P + +EW    Q +  +  I         ++ I  T+  + G Y C A N YG   +
Sbjct: 3027 GAAP-ISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHGTYRCVASNAYGVAQS 3081

Query: 3236 RATINCYG 3243
               ++ +G
Sbjct: 3082 VVNLSVHG 3089



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/306 (24%), Positives = 118/306 (38%), Gaps = 46/306 (15%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P +  +  +S++ EG        ++G    +VTW K G  L    +H++    + + LR+
Sbjct: 2416 PTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV----HGSRLRL 2469

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
                 +DSG Y         C V       E+     +Q + S   + +Q      RIE 
Sbjct: 2470 LQVTPADSGEYV--------CRVVGSSGTQEASVLVTIQQRLSG--SHSQGVAYPVRIES 2519

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            S  +LA              G     +C V  +    +TW+     +     H+I+ +  
Sbjct: 2520 SSASLA-------------NGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGSR- 2563

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQV--VAPKFVERFSTLN 501
                L I  VT +DSG   C   N +G  ET+    +       V  V+P      S+  
Sbjct: 2564 ----LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPT 2619

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + LN      P   ITW K G   +P+   R  T G  S L + +   +D+  Y
Sbjct: 2620 VVEGQTLDLNCVVARQPQAIITWYKRG-GSLPS---RHQTHG--SHLRLHQMSVADSGEY 2673

Query: 562  QCTAQN 567
             C A N
Sbjct: 2674 VCRANN 2679



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 55/212 (25%), Positives = 79/212 (37%), Gaps = 19/212 (8%)

Query: 368  SQYITDTQQRETEERIEISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
            +Q    T Q++ E  ++    A  APQ      +  V  G      C  TG P P + W 
Sbjct: 3166 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW- 3224

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
             +  +    + H++     G+  L+I  V   DSG   C A + +G       L+V  + 
Sbjct: 3225 -SKLRSPLPWQHRL----EGD-TLIIPRVAQQDSGQYICNATSPAGHAEATIILHV--ES 3276

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
               A    E  S   V+ GE V L   A GTP     W + G  +      R        
Sbjct: 3277 PPYATTVPEHAS---VQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR------NE 3327

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             L   RA   D+  Y+C   N  GS    A+L
Sbjct: 3328 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQL 3359



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 39/165 (23%), Positives = 61/165 (36%), Gaps = 12/165 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S  I W   G ++    R        +  L I    T D+G Y C AT+  G A+  
Sbjct: 1960 GVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCVATSPAGTAQAR 2016

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
            +++  +  S    P       +   + +GQ+    C V        ++ WY  G  +   
Sbjct: 2017 IQVVVLSASDASPPPVKIE-SSSPSVTEGQTLDLNCVV--AGSAHAQVTWYRRGGSLPPH 2073

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
            T++          L +      DSGEYVCR  N  G      T++
Sbjct: 2074 TQVHGSR------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2112



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 8/108 (7%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            + P + T +    S+   ET + +C LA  G P +  +W   G  L    R T   +   
Sbjct: 3275 ESPPYATTVPEHASVQAGETVQLQC-LAH-GTPPLTFQWSRVGSSL--PGRATARNEL-- 3328

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP 4078
              ++F    PEDSG Y CR TN  G  E  A +   G PG +  + +P
Sbjct: 3329 --LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIP 3374



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 46/153 (30%), Positives = 61/153 (39%), Gaps = 23/153 (15%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+  G ++ + H+I      G   L I      DSG Y C  +N  G  E S+ +   
Sbjct: 2544 ITWYKRGGSLPSRHQI-----VGSR-LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2597

Query: 3142 DKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQ--PMRHS 3195
                   P  +  I+ IE     + +GQ+    C V     P   I WY  G   P RH 
Sbjct: 2598 GSGSSHVPSVSPPIR-IESSSPTVVEGQTLDLNCVVAR--QPQAIITWYKRGGSLPSRHQ 2654

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            T     S      + +A     DSGEYVCRA N
Sbjct: 2655 TH---GSHLRLHQMSVA-----DSGEYVCRANN 2679



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 29/218 (13%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            +I W+  G ++ + H+    +      L +      DSG Y CRA N     E S+ +  
Sbjct: 2639 IITWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVIS- 2691

Query: 3141 VDKSKG--QKPRFTTHIQ---NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG--QPMR 3193
            V  S G    P  +  I+   +   + +G++    C VVP      ++ W+  G   P  
Sbjct: 2692 VSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC-VVP-GQAHAQVTWHKRGGSLPSH 2749

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATINCYGKGGVYLES 3251
            H TR           L + +    DSGEYVCR     G  E     TI   G   V++ +
Sbjct: 2750 HQTRGSR--------LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPA 2801

Query: 3252 LQPDSLAKIR-ELESLQGAQQQTPSTPSAEPPKFITQI 3288
              P     IR E  S + A+ QT       P +   Q+
Sbjct: 2802 --PGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQV 2837



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQ 3165
            VL+I   K +D+GTY C A N  G A+  V++  VD             +  E  ++ G 
Sbjct: 3148 VLQISSAKPSDAGTYVCLAQNALGTAQKQVEV-IVDTGAMAPGAPQVQAEEAELTVEAGH 3206

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A   C+      P   I W     P+    R++   D     L I      DSG+Y+C 
Sbjct: 3207 TATLRCSA--TGSPAPTIHWSKLRSPLPWQHRLE--GD----TLIIPRVAQQDSGQYICN 3258

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
            A +  G     ATI  + +   Y  ++   +  +  E   LQ     TP
Sbjct: 3259 ATSPAGH--AEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTP 3305



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/52 (42%), Positives = 27/52 (51%)

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAF 2996
            I W  N   +    R  +TS+ G  TL + DV E D G YTC+A N RG  F
Sbjct: 417  INWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVF 468



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 52/218 (23%), Positives = 76/218 (34%), Gaps = 13/218 (5%)

Query: 385  ISEKALAPQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWFIND-RQIRDDYNHKILV 442
            + E   AP  V+V   R +  +G      C+V+G P     W   D R +      +   
Sbjct: 1648 LPETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQG 1707

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +E     L   +V  SD+GV  C  RN       +  L V E         VE   + +V
Sbjct: 1708 SE-----LHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSV 1762

Query: 503  REGEPVVLNARAVG-TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            R G  V     A   +P   + W +     + N +L          L I   + SDA  Y
Sbjct: 1763 RPGADVTFICTAKSKSPAYTLVWTR-----LHNGKLPTRAMDFNGILTIRNVQLSDAGTY 1817

Query: 562  QCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPT 599
             CT  N+       A L+             +H P+ T
Sbjct: 1818 VCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT 1855



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 56/276 (20%), Positives = 97/276 (35%), Gaps = 14/276 (5%)

Query: 85   QGGNAKFEGKLRGNPTPV-VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
            QG +A F+  +     P+ + W  +   L E N +        G + + I    P + G 
Sbjct: 3014 QGQDASFKCLIHDGAAPISLEWKTRNQEL-EDNVHI----SPNGSI-ITIVGTRPSNHGT 3067

Query: 144  YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR-HVSETVEHKAYGTQGYTTEQSR 202
            Y C A N YG A   V +   G              +   + T+E  + G    +   +R
Sbjct: 3068 YRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTR 3127

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262
             +   A      +   D   V         +      + +  +G +  Q+   +D     
Sbjct: 3128 ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMA 3187

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
               P++  +     ++ G  A  +   +G+P P + W K    L   ++ E        T
Sbjct: 3188 PGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLE------GDT 3241

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L +    + DSG Y   A +P G    +  L VESP
Sbjct: 3242 LIIPRVAQQDSGQYICNATSPAGHAEATIILHVESP 3277



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 12/117 (10%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            T+  + +  +AL PQ + + Q+  V  G    F C  +G P P+++W   D  +  D   
Sbjct: 3543 TQSHVLLLVQAL-PQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPD--- 3597

Query: 439  KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
                +   N+ LM+ +V   D+G   C A N+ G+      L V E+   V P F +
Sbjct: 3598 ----SRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER---VVPYFTQ 3647



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 1/84 (1%)

Query: 265 PPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           PP++   PR S +   G    F     G P P + W  N   + +  +  + +     TL
Sbjct: 384 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 443

Query: 324 RVRNTQKSDSGHYTLLAENPNGCI 347
            +R+ ++SD G YT  A N  G +
Sbjct: 444 IIRDVKESDQGAYTCEAMNARGMV 467



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 55/218 (25%), Positives = 79/218 (36%), Gaps = 27/218 (12%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H+          +L +      DSG
Sbjct: 2142 VAEGQTL--DLNCVVPGQAHAQVTWHKRGGSLPARHQTHGS------LLRLHQVTPADSG 2193

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDD 3178
             Y C      G  E SV L  ++ S    P     I++    + +GQ+    C V     
Sbjct: 2194 EYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA--GQ 2250

Query: 3179 PDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
               ++ WY  G   P RH  R           L I      D+G+YVCRA N      T 
Sbjct: 2251 AHAQVTWYKRGGSLPARHQVRGSR--------LYIFQASPADAGQYVCRASNGMEASITV 2302

Query: 3237 ATINCYGKGGVY-LESLQPDSLAKIRELESLQGAQQQT 3273
                  G    Y   S QP  +    E  S Q A+ QT
Sbjct: 2303 TVTGTQGANLAYPAGSTQPIRI----EPSSSQVAEGQT 2336



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 62/267 (23%), Positives = 97/267 (36%), Gaps = 46/267 (17%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            DSG Y C AT+  G AE ++ L        + P + T +     ++ G++   +C  +  
Sbjct: 3251 DSGQYICNATSPAGHAEATIILHV------ESPPYATTVPEHASVQAGETVQLQC--LAH 3302

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P +  +W   G  +      +        +L        DSG Y CR  NK G     
Sbjct: 3303 GTPPLTFQWSRVGSSLPGRATARNE------LLHFERAAPEDSGRYRCRVTNKVGSAEAF 3356

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +   G  G                  SL        STP+ +    +T  Q  TK + 
Sbjct: 3357 AQLLVQGPPG------------------SLPATSIPAGSTPTVQ----VTP-QLETKSI- 3392

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356
            G S  F    VP  D   ++ WF  G +LP GH  +        +L I    +   G Y 
Sbjct: 3393 GASVEFHC-AVP-SDRGTQLRWFKEGGQLPPGHSVQD------GVLRIQNLDQSCQGTYI 3444

Query: 3357 CVATNKLGRDSTKANLKCTSKENLILD 3383
            C A    G+    A L   +  +++++
Sbjct: 3445 CQAHGPWGKAQASAQLVIQALPSVLIN 3471



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 636 PPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPQ + P + S+ A  G  + F      +G PT  I W  N   I +  R T     G  
Sbjct: 384 PPQVVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG 441

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGV 719
           +L +  +   D G YTC A++A G+
Sbjct: 442 TLIIRDVKESDQGAYTCEAMNARGM 466



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
            V T P + I+ +  Q   F    + +G P   + W  N   I +  R+T   + G   L 
Sbjct: 387  VVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 444

Query: 1772 MKYVNPEDSGTYTCRAINELG 1792
            ++ V   D G YTC A+N  G
Sbjct: 445  IRDVKESDQGAYTCEAMNARG 465



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + S  P    +  S TV E + +   C V     P+  I WY+ G  LPS H+    +  
Sbjct: 2604 VPSVSPPIRIESSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH-- 2659

Query: 3885 GFVSLDILYVYAEDSGEYICRAVND 3909
                L +  +   DSGEY+CRA N+
Sbjct: 2660 ----LRLHQMSVADSGEYVCRANNN 2680



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 55/239 (23%), Positives = 89/239 (37%), Gaps = 44/239 (18%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            +S   + EG      C V     P   I W+  G  + + H+   +H      L +    
Sbjct: 2615 SSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH------LRLHQMS 2666

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE 2235
              DSG Y+C+A N +           A   +I++      G        A G S  I +E
Sbjct: 2667 VADSGEYVCRANNNID----------ALEASIVISVSPSAGSPS-----APGSSMPIRIE 2711

Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295
                           ++HV EG+T    C V      + ++ ++  G +L S    H T 
Sbjct: 2712 S-------------SSSHVAEGETLDLNCVVPG--QAHAQVTWHKRGGSLPS---HHQTR 2753

Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  L + H  P D+GEY  + + + G   +++ +T+ A GS       P G   IR
Sbjct: 2754 GS---RLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIR 2809



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 390 LAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           + PQ V   ++    + G+   F C   G P P + W +N   I   +    + +E G  
Sbjct: 383 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHI-PSHPRVTVTSEGGRG 441

Query: 449 ALMITNVTLSDSGVVTCVARNKSG 472
            L+I +V  SD G  TC A N  G
Sbjct: 442 TLIIRDVKESDQGAYTCEAMNARG 465



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 62/244 (25%), Positives = 91/244 (37%), Gaps = 46/244 (18%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            + +     +PP   +E   +  V EG  +  +C V   G    ++ W+  G      ++V
Sbjct: 2020 VVLSASDASPPPVKIE-SSSPSVTEGQTLDLNCVV--AGSAHAQVTWYRRGGSLPPHTQV 2076

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMS 3804
            H         L +  +   D+GEY CR  N  GS    A IT S     VL         
Sbjct: 2077 HGSR------LRLPQVSPADSGEYVCRVEN--GSGPKEASITVS-----VLHG------- 2116

Query: 3805 GEKIKELERGRISDAPKEEPIV-STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
                           P   P+  ST P  I    SH V E + +   C V P +    ++
Sbjct: 2117 -----------THSGPSYTPVPGSTRPIRIEPSSSH-VAEGQTLDLNC-VVPGQ-AHAQV 2162

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKATISC 3921
             W++ G  LP+ H+       G + L +  V   DSGEY+C  V   G  E     TI  
Sbjct: 2163 TWHKRGGSLPARHQTH-----GSL-LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEA 2216

Query: 3922 KKLP 3925
              +P
Sbjct: 2217 SVIP 2220



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 2495 ERRSEEPDREFEKPIFT-QVLTGPSELWEGQHAHYEA-RVVPVGDPSLRFEWYINGVELK 2552
            +  S+ PDR  E      QV+T P E  +           V +G P+    W +N   + 
Sbjct: 368  DEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIP 427

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
               R   T + G  TL I  V  +D G Y C+A+N  G
Sbjct: 428  SHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 465



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 1/90 (1%)

Query: 4505 RQGRGGIVPPSF-TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
            R    G +PP   T   +++  + GQ V       G     + W  N   +    R  + 
Sbjct: 376  RSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVT 435

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
             E G  TL+I +    D G Y C A+N+ G
Sbjct: 436  SEGGRGTLIIRDVKESDQGAYTCEAMNARG 465



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR-NGVPIEASNRLTTMHDFGYVAL 1770
            V  +P   + V   +A   E   +  G+P+    W R +  P +   R   + D  +  L
Sbjct: 3093 VSVLPEGPVWVKVGKAVTLEC--VSAGEPRSSARWTRISSTPAKLEQRTYGLMD-SHAVL 3149

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +    P D+GTY C A N LG A     + V + A
Sbjct: 3150 QISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGA 3185



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 5/99 (5%)

Query: 3035 EPGQQPD--DDTG-RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI 3091
            E    PD  D+ G  PP+  T  ++ +  S GQ   +  + +  G  + +I W  N   I
Sbjct: 369  EESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTF--TCVAIGVPTPIINWRLNWGHI 426

Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
             +  R+      G   L I   K +D G Y+C A N  G
Sbjct: 427  PSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 465



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q+GQ A F C LI  G   + +EW    + +ED+  I+         +TI   R  + G
Sbjct: 3012 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGSI----ITIVGTRPSNHG 3066

Query: 2448 VYMCRASNLLG 2458
             Y C ASN  G
Sbjct: 3067 TYRCVASNAYG 3077



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     +++I    G  V F C    +G PT  I+W  N     +  RV   ++ G  
Sbjct: 384  PPQVVTPPRESIQASRGQTVTFTCVA--IGVPTPIINWRLNWGHIPSHPRVTVTSEGGRG 441

Query: 3754 ALDIDYIYARDAGEYTCRATNKWG 3777
             L I  +   D G YTC A N  G
Sbjct: 442  TLIIRDVKESDQGAYTCEAMNARG 465



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 38/178 (21%)

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            L + H      L +  V P DSG Y C   N  G   TS  + +Q        S H  ++
Sbjct: 2553 LPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG-----SSHVPSV 2607

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
                ++E SS                        PT + EGQ+    C +     P   +
Sbjct: 2608 SPPIRIESSS------------------------PTVV-EGQTLDLNCVVAR--QPQAII 2640

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             WY  G  L S H+   S+      L +  +   DSGEY C+A NN+    +SI ++V
Sbjct: 2641 TWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2692



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+ +T      + S GQ+  + C     P P   + W  N   + S  R   +++ G   
Sbjct: 385  PQVVTPPRESIQASRGQTVTFTCVAIGVPTPI--INWRLNWGHIPSHPRVTVTSEGGRGT 442

Query: 1904 LDILTVYGEDSGEYTCKAINNLG 1926
            L I  V   D G YTC+A+N  G
Sbjct: 443  LIIRDVKESDQGAYTCEAMNARG 465



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 12/122 (9%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI--RAGHRYRTTHDF 2164
            + P + T +    +++ G+    +C       P LT  W   G  +  RA  R    H F
Sbjct: 3275 ESPPYATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLPGRATARNELLH-F 3331

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
               A        EDSG Y C+ TNK+G A     L V G    +  T  P G     Q+ 
Sbjct: 3332 ERAA-------PEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3384

Query: 2225 AQ 2226
             Q
Sbjct: 3385 PQ 3386



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 6/66 (9%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P L  +W R G  +    R T  ++     L+ +   PEDSG Y CR  N++G A   
Sbjct: 3303 GTPPLTFQWSRVGSSLPG--RATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAF 3356

Query: 1798 STLFVQ 1803
            + L VQ
Sbjct: 3357 AQLLVQ 3362



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 10/111 (9%)

Query: 3825 IVSTPPKFITQIKS--HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            ++   P  +  I++   TV     V FEC      DPK ++ W + G     GH    + 
Sbjct: 3461 VIQALPSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GHLRPGIV 3513

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
              G V + I +V   D+G+Y C A N  G   +   +  + LP I +  +V
Sbjct: 3514 QSGGV-VRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEV 3563



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 10/110 (9%)

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +EP   +  +  +  V ++  S+   V+EG+ + L C +   G    +V W   G S+  
Sbjct: 2403 IEPAGSVPALGVTPTVRIE--SSSSQVAEGQTLDLNCLVA--GQAHAQVTWHKRGGSLP- 2457

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             +R + +       L ++  T AD+GEY  R V   G+   S +V + +R
Sbjct: 2458 -ARHQVHGS----RLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2502



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 53/231 (22%), Positives = 77/231 (33%), Gaps = 45/231 (19%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P   +     +VAE Q    +   +  G    +V W + G        L   H      L
Sbjct: 2416 PTVRIESSSSQVAEGQT--LDLNCLVAGQAHAQVTWHKRG------GSLPARHQVHGSRL 2467

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +  V P DSG Y CR +   G    S  + +Q +    L   H   +    ++E SS  
Sbjct: 2468 RLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR----LSGSHSQGVAYPVRIESSS-- 2521

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
                                     L+ G +    C +     P+  + WY  G  L S 
Sbjct: 2522 -----------------------ASLANGHTLDLNCLVASQA-PH-TITWYKRGGSLPSR 2556

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            H+   S       L I  V   DSGEY C   N  G   +S+ + +Q   S
Sbjct: 2557 HQIVGSR------LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2601



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 1568 DMVDEVTTQAP-ICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF 1626
            D  DE     P + T   ++++   GQ   F    + +   T  + W  N   + S  R 
Sbjct: 375  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFT--CVAIGVPTPIINWRLNWGHIPSHPRV 432

Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            T T+  G   L I      D G YTC A+NA G
Sbjct: 433  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 465



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 2/83 (2%)

Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
           P+  TP ++ I    G    F      IG  T  + W  +   + +  R+T     G   
Sbjct: 385 PQVVTPPRESIQASRGQTVTFTC--VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGT 442

Query: 969 LTIKSVTVHDAGHYTCRAYNAIG 991
           L I+ V   D G YTC A NA G
Sbjct: 443 LIIRDVKESDQGAYTCEAMNARG 465



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            +I    G  + F C       PT  I W  N   +PS  R   T +    +L I    E 
Sbjct: 394  SIQASRGQTVTFTCVAIGV--PTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 451

Query: 2842 DSGIYTCKATNSKG 2855
            D G YTC+A N++G
Sbjct: 452  DQGAYTCEAMNARG 465



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 20/129 (15%)

Query: 3978 QIQSQTSLV-EMETTKFECQLAPVGDPNMKVEWFFNGK--PLLHKNRFTPIYDFGYVAMN 4034
            +I+S +S V E +T    C +A  G  + +V W+  G   P  H+ R + +Y F      
Sbjct: 2227 RIESSSSTVAEGQTLDLSCVVA--GQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ----- 2279

Query: 4035 FGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASW 4094
                 P D+G+Y+CRA+N  GM E    +  TG  G    + L     S + IR   +S 
Sbjct: 2280 ---ASPADAGQYVCRASN--GM-EASITVTVTGTQG----ANLAYPAGSTQPIRIEPSSS 2329

Query: 4095 QVTPEQVVE 4103
            QV   Q ++
Sbjct: 2330 QVAEGQTLD 2338



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 9/92 (9%)

Query: 3823 EPIVSTPPKFIT---QIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            EP  S P   +T   +I+S + + +EG   +           ++ W++ G  LP+ H+  
Sbjct: 2404 EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVH 2463

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                     L +L V   DSGEY+CR V   G
Sbjct: 2464 GS------RLRLLQVTPADSGEYVCRVVGSSG 2489



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 10/97 (10%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S S P+ ++  S+ P V EG+ + L C +     P   + W+  G S+   SR +T+   
Sbjct: 2606 SVSPPIRIE--SSSPTVVEGQTLDLNCVVARQ--PQAIITWYKRGGSLP--SRHQTHGSH 2659

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
                L +   + AD+GEY  RA N++ +   S ++ V
Sbjct: 2660 ----LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2692



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            ++P+ +    +  +++GQ A F + LI    A + +EW   N+ L+     +   +    
Sbjct: 2999 RSPVISIDPPSSTVQQGQDASF-KCLIHDGAAPISLEWKTRNQELEDNVHISPNGSI--- 3054

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             + I+   P + GTY C A NA G A +     VH   ++
Sbjct: 3055 -ITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTV 3093



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 11/124 (8%)

Query: 3826 VSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V +PP + T +  H +V+  E V+ +C       P L  +W R G  LP     R     
Sbjct: 3274 VESPP-YATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARNEL-- 3328

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
                L       EDSG Y CR  N  G     A +  +  P  +    +P G   +  +T
Sbjct: 3329 ----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3384

Query: 3945 -QME 3947
             Q+E
Sbjct: 3385 PQLE 3388



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDP--NLRIEFYHNGKALQSAARFHITFDFG 2298
            PP+ VT  R +     G+T  F C    V  P  N R+ + H    + S  R  +T + G
Sbjct: 384  PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGH----IPSHPRVTVTSEGG 439

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALG 2324
              +L I+     D G Y+ +A+NA G
Sbjct: 440  RGTLIIRDVKESDQGAYTCEAMNARG 465



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 8/96 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APV ++    +  ++ G+ A F    T +  P L+    W G     G +          
Sbjct: 1844 APVVSIHPPQL-TVQPGQLAEFRCSATGSPTPTLE----WTGGP---GGQLPAKAQIHGG 1895

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            IL +    P D  +YLCRA+++ G+ V  A + V G
Sbjct: 1896 ILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHG 1931



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 9/85 (10%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            S+ P  I    SH V E E +   C V P +    ++ W++ G  LPS H+ R       
Sbjct: 2704 SSMPIRIESSSSH-VAEGETLDLNC-VVPGQ-AHAQVTWHKRGGSLPSHHQTRGS----- 2755

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
              L + +V   DSGEY+CR +   G
Sbjct: 2756 -RLRLHHVSPADSGEYVCRVMGSSG 2779



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 9/87 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            +  R   G  A F     G PTP +SW++           S+  + +  +  L++  + P
Sbjct: 3561 QEVRVPAGSAAVFPCIASGYPTPDISWSKLDG--------SLPPDSRLENNMLMLPSVRP 3612

Query: 139  GDEGEYTCTARNQYGEAICSVYIQ-PE 164
             D G Y CTA N+ G+     ++Q PE
Sbjct: 3613 QDAGTYVCTATNRQGKVKAFAHLQVPE 3639



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP+  T P + I  S   +  F C  I V   +  + W  N   + +  RV   ++ G  
Sbjct: 384  PPQVVTPPRESIQASRGQTVTFTCVAIGV--PTPIINWRLNWGHIPSHPRVTVTSEGGRG 441

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHG 3639
             L I  V + D G YTC+A N  G
Sbjct: 442  TLIIRDVKESDQGAYTCEAMNARG 465



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 9/95 (9%)

Query: 3822 EEPIVSTP-PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            E  ++  P P    +  S TV E + +   C V  +   +  + WY+ G  LP+ H+ R 
Sbjct: 2215 EASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQ--VTWYKRGGSLPARHQVRG 2272

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT 3915
                    L I      D+G+Y+CRA N      T
Sbjct: 2273 ------SRLYIFQASPADAGQYVCRASNGMEASIT 2301



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 244  YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
            YVG   VQ    +  +    +P  +   P  S + +G     + Q+SG+P     W +  
Sbjct: 1636 YVGNPSVQGGQCLPET--NQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSRED 1693

Query: 304  QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESPTESY 362
             R + S   +    H  + L   + Q SD+G Y     N +    +   L V E+P++  
Sbjct: 1694 GRPVPSGTQQ---RHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPI 1750

Query: 363  ---VQDQRSQYI 371
               V++QRSQ +
Sbjct: 1751 TVTVEEQRSQSV 1762



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S   V EGQ +   C +     ++ +V W K G  +   H+   +H      L ++ +  
Sbjct: 2423 SSSQVAEGQTLDLNCLV--AGQAHAQVTWHKRGGSLPARHQ---VHGS---RLRLLQVTP 2474

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRLT 1535
             DSG Y CR V   GT E S  +T
Sbjct: 2475 ADSGEYVCRVVGSSGTQEASVLVT 2498



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            D  DE   + P+ VT P+       GQ V F C    V      + W  N   +    R 
Sbjct: 375  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPI--INWRLNWGHIPSHPRV 432

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
                + G   L I D+   D G YTC A+N  G
Sbjct: 433  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 465



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 8/108 (7%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +PP  TT P    +    +   +C  +      +  +W   G  L    R    N+    
Sbjct: 3276 SPPYATTVPEHASVQAGETVQLQC--LAHGTPPLTFQWSRVGSSL--PGRATARNE---- 3327

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663
            +L        D+G Y C+ TN+ G A    +L V+G  G +    +P+
Sbjct: 3328 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPA 3375



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/70 (25%), Positives = 33/70 (47%), Gaps = 2/70 (2%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           ++G    F     G PTP+++W      +    + ++    + G  +L+I+ +   D+G 
Sbjct: 398 SRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTV--TSEGGRGTLIIRDVKESDQGA 455

Query: 144 YTCTARNQYG 153
           YTC A N  G
Sbjct: 456 YTCEAMNARG 465



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+   +R +T+     
Sbjct: 2130 TRPIRIEPSSSH--VAEGQTLDLNCVVP--GQAHAQVTWHKRGGSLP--ARHQTHGSL-- 2181

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +   T AD+GEY    V   G    S +V +
Sbjct: 2182 --LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2214



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P +I    SH V E + +   C V P +    ++ WY+ G  LP+ H+           L
Sbjct: 2905 PIYIEASSSH-VTEGQTLDLNC-VVPGQ-AHAQVTWYKRGGSLPARHQTHGS------QL 2955

Query: 3890 DILYVYAEDSGEYICRAVNDFGED 3913
             +  V   DSGEY+CRA +  G +
Sbjct: 2956 RLHLVSPADSGEYVCRAASGPGPE 2979



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 25/55 (45%)

Query: 4090 MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            M A  Q T    V+ S     PV    P  +TV+ G+ A F C  TG P P + W
Sbjct: 1824 MFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1878



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S + P  V+  S+ P V+EG+ + L C +   G    +V W+  G S+   ++       
Sbjct: 2025 SDASPPPVKIESSSPSVTEGQTLDLNCVVA--GSAHAQVTWYRRGGSLPPHTQVHGS--- 2079

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
                L +   + AD+GEY  R  N  G    S  V V+
Sbjct: 2080 ---RLRLPQVSPADSGEYVCRVENGSGPKEASITVSVL 2114



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+ V  R +T+     
Sbjct: 2319 TQPIRIEPSSSQ--VAEGQTLDLNCVVP--GQSHAQVTWHKRGGSLPV--RHQTHGSL-- 2370

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +  A+ AD+GEY  R +        S +V +
Sbjct: 2371 --LRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2403



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 8/96 (8%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P   +   S T +EG  +     +     P   I W K G S+ +  +        ++ L
Sbjct: 2609 PPIRIESSSPTVVEGQTLDLNCVV--ARQPQAIITWYKRGGSLPSRHQTHG----SHLRL 2662

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
              +S  + DSGEY CRA +     E   V+ V+P A
Sbjct: 2663 HQMS--VADSGEYVCRANNNIDALEASIVISVSPSA 2696



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 3695 PRFTVEIKDNID-VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P   + I+ ++  V  G  V F+C    +GDP  ++ W   G     G     +   G +
Sbjct: 3466 PSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVV 3519

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL--ESQLPQG 3802
               I ++   DAG+Y C ATN  G+  +   +   A   I +  E ++P G
Sbjct: 3520 R--IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAG 3568



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 10/123 (8%)

Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVAL 2169
            V +   TS++ +  G    FEC    + DP   + W   G  +R G         G V  
Sbjct: 3468 VLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVVR- 3520

Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL--DTQHPNGLEKIRQLEAQG 2227
             I +    D+G Y C ATN  G   +   L V     I +  + + P G   +    A G
Sbjct: 3521 -IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCIASG 3579

Query: 2228 HST 2230
            + T
Sbjct: 3580 YPT 3582



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 12/80 (15%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP--IHDFGYVALDIIDL 1509
            S++ V+ G  V FEC    + D   +V W K G     GH  RP  +   G V +  ++L
Sbjct: 3475 SVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GH-LRPGIVQSGGVVRIAHVEL 3526

Query: 1510 IAEDSGIYTCRAVNLVGTDE 1529
               D+G Y C A N  GT +
Sbjct: 3527 A--DAGQYRCTATNAAGTTQ 3544



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 9/100 (9%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++   P  +MP +++RV    AA F    I  G P   + W +    +   +RL      
Sbjct: 3550 LVQALPQISMP-QEVRVPAGSAAVFPC--IASGYPTPDISWSKLDGSLPPDSRLENN--- 3603

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                L +  V P+D+GTY C A N  G+    + L V  +
Sbjct: 3604 ---MLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 3640


>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens cDNA
            FLJ31982 fis, clone NT2RP7008550, highly similar to Mus
            musculus rig-1 protein mRNA. ).
          Length = 1034

 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 105/401 (26%), Positives = 158/401 (39%), Gaps = 52/401 (12%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKN-SPDFQIHTFSTKSILIIRQVFVE------DS 4478
            E A      +G P P I+WY+    +     D + H     S  +     V       D 
Sbjct: 79   EPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARPDE 138

Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD-TKV 4537
             V+  VA N  G A  S N  +E         ++   F  +  NV V  G+   L+    
Sbjct: 139  GVYTCVARNYLGAA-ASRNASLEV-------AVLRDDFRQSPGNVVVAVGEPAVLECVPP 190

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
             G     V W K+G +++ +   +I    G   L++      D+G Y CVA N AGE   
Sbjct: 191  RGHPEPSVSWRKDGARLKEE-EGRITIRGGK--LMMSHTLKSDAGMYVCVASNMAGERES 247

Query: 4598 DAECVVSL--PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
             A  V+ L  P+   +P  Q   A+AP                 + F C++ G P P ++
Sbjct: 248  AAAEVMVLERPSFLRRPVNQVVLADAP-----------------VTFLCEVKGDPPPRLR 290

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            W K D  +   +Y        +++L I     EDEG Y CVA NS GR   +  L V  P
Sbjct: 291  WRKEDGELPTGRY----EIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVP 346

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
             Q      +T  +D +   G+   F+ +      P I W +EG+ +   P   +   G  
Sbjct: 347  PQ-----LVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRF 401

Query: 4776 AV-----LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +V     L I      D G + C+A + AG +   A L +K
Sbjct: 402  SVSPRGQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIK 442



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 94/384 (24%), Positives = 160/384 (41%), Gaps = 44/384 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W ++   +K   + +I     K  L++      D+ ++  VA N  G  + +
Sbjct: 192  GHPEPSVSWRKDGARLKEE-EGRITIRGGK--LMMSHTLKSDAGMYVCVASNMAGERESA 248

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            A  V+  +R         PSF     N  V +   V    +V G  P  + W K   ++ 
Sbjct: 249  AAEVMVLER---------PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL- 298

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P  R +I  +   ++L I     +D G Y CVA NS G A       V            
Sbjct: 299  PTGRYEIRSD---HSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSV------------ 343

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYFQMS- 4672
                + PP+++   +D++ A G+++ F C+  G P P + W K     L+ PS+  Q + 
Sbjct: 344  ----HVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTG 399

Query: 4673 --RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT---PL 4727
                +    L I+     D G Y C A + AG +   A L++ +    D LP +    P 
Sbjct: 400  RFSVSPRGQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEI-KGASLDGLPPVILQGPA 458

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
               +V  G       ++T   +P+++W ++G  + +  D Q     N   L I N  E D
Sbjct: 459  NQTLVL-GSSVWLPCRVTGNPQPSVRWKKDGQWL-QGDDLQFKTMANGT-LYIANVQEMD 515

Query: 4788 TGTFTCRATTAAGQVETSAKLVVK 4811
             G ++C A ++ G+   S  L ++
Sbjct: 516  MGFYSCVAKSSTGEATWSGWLKMR 539



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 90/351 (25%), Positives = 141/351 (40%), Gaps = 39/351 (11%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F ++     V       F  E  G+P P ++W +E+  +   P  +    S  S L I
Sbjct: 258  PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL---PTGRYEIRSDHS-LWI 313

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
              V  ED   +  VAEN  G A+ S +L V           VPP      Q+     G+ 
Sbjct: 314  GHVSAEDEGTYTCVAENSVGRAEASGSLSVH----------VPPQLVTQPQDQMAAPGES 363

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT------LLILEAYPQDSGKY 4584
            V    +  G  P  ++W K G +V     ++ L+  G ++      L I      D+G Y
Sbjct: 364  VAFQCETKGNPPPAIFWQKEGSQVLL-FPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYY 422

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C A++ AG     A   +   A+ D           PP I++   ++ +  G ++   C
Sbjct: 423  MCQAVSVAGSILAKALLEIK-GASLD---------GLPPVILQGPANQTLVLGSSVWLPC 472

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            ++ G P P+V+W K  + ++        +T    TL I+     D G Y CVA +S G  
Sbjct: 473  RVTGNPQPSVRWKKDGQWLQGDDL--QFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEA 530

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ-FKTQITSKIKPTIQW 4754
            T +  LK+ +       P   P        G P+Q   T+IT K   T+ W
Sbjct: 531  TWSGWLKMREDWGVSPDPPTEPSSP----PGAPSQPVVTEIT-KNSITLTW 576



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 60/192 (31%), Positives = 85/192 (44%), Gaps = 13/192 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI----RDDYNHKILVNESGN 447
           P+ V+   D  V+ G+     CR  GRP P + W+ N  ++     D   H++L+     
Sbjct: 64  PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123

Query: 448 HALMITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
               I +   +  D GV TCVARN  G  A +   N   +  V+   F +    + V  G
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASR---NASLEVAVLRDDFRQSPGNVVVAVG 180

Query: 506 EPVVLN-ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           EP VL      G P P ++W+KDG   +   E RI   GG   L +     SDA  Y C 
Sbjct: 181 EPAVLECVPPRGHPEPSVSWRKDGAR-LKEEEGRITIRGG--KLMMSHTLKSDAGMYVCV 237

Query: 565 AQNVAGSTATRA 576
           A N+AG   + A
Sbjct: 238 ASNMAGERESAA 249



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 56/192 (29%), Positives = 81/192 (42%), Gaps = 15/192 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F++   ++ V       F C V G P P + W   D ++     ++I      +H+L 
Sbjct: 258 PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTG-RYEI----RSDHSLW 312

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I +V+  D G  TCVA N  G       L+V      V P+ V +        GE V   
Sbjct: 313 IGHVSAEDEGTYTCVAENSVGRAEASGSLSVH-----VPPQLVTQPQDQMAAPGESVAFQ 367

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST-----LDIPRAKASDAAWYQCTAQ 566
               G P P I WQK+G  ++  P   +   G  S      L+I   +  DA +Y C A 
Sbjct: 368 CETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAV 427

Query: 567 NVAGSTATRARL 578
           +VAGS   +A L
Sbjct: 428 SVAGSILAKALL 439



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 18/201 (8%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI-----KPSKYFQMSRT 4674
            +A P I+E   D +V+ G+     C+  G+P P ++WYK    +      P  +  +  +
Sbjct: 61   DAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPS 120

Query: 4675 ADEYTLRI--SEAFPEDEGDYKCVAYNSAGRVTVA-AKLKV-TQPDQADNLPALTPLRDI 4730
               +  RI        DEG Y CVA N  G      A L+V    D     P      ++
Sbjct: 121  GALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPG-----NV 175

Query: 4731 VVYEGQPAQFK-TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            VV  G+PA  +        +P++ W ++GA + E      I  G    L++ +T + D G
Sbjct: 176  VVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGK---LMMSHTLKSDAG 232

Query: 4790 TFTCRATTAAGQVETSAKLVV 4810
             + C A+  AG+ E++A  V+
Sbjct: 233  MYVCVASNMAGERESAAAEVM 253



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 89/391 (22%), Positives = 144/391 (36%), Gaps = 43/391 (10%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P VSW +  A L E      R   + G   L++      D G Y C A N  GE 
Sbjct: 191 RGHPEPSVSWRKDGARLKE---EEGRITIRGG--KLMMSHTLKSDAGMYVCVASNMAGE- 244

Query: 156 ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTE-QSRQTQKVAYTNGTD 214
                 +                 R V++ V   A  T  +  E +     ++ +     
Sbjct: 245 ------RESAAAEVMVLERPSFLRRPVNQVVLADAPVT--FLCEVKGDPPPRLRWRKEDG 296

Query: 215 HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRN 274
              T  +++ +     +  VS  +  T   V E+ V    E   SL    PP++  +P++
Sbjct: 297 ELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVG-RAEASGSLSVHVPPQLVTQPQD 355

Query: 275 SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
                G    FQ +  GNP P + W K G +++      +  T                G
Sbjct: 356 QMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPT----------------G 399

Query: 335 HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQF 394
            +++   +P G +      AV+     Y   Q          +   E    S   L P  
Sbjct: 400 RFSV---SPRGQL---NITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDGLPPVI 453

Query: 395 VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR-DDYNHKILVNESGNHALMIT 453
           ++   ++ +  G      CRVTG P P V W  + + ++ DD   K + N +    L I 
Sbjct: 454 LQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGT----LYIA 509

Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
           NV   D G  +CVA++ +GE  +   L + E
Sbjct: 510 NVQEMDMGFYSCVAKSSTGEATWSGWLKMRE 540



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 54/199 (27%), Positives = 78/199 (39%), Gaps = 13/199 (6%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN-----FPIKNSPDF 4457
            G +    PP    + Q       E   F+ E  G P P I W +E      FP ++    
Sbjct: 339  GSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPT 398

Query: 4458 QIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT 4517
               + S +  L I  V   D+  +   A +  G+    A L ++     G    +PP   
Sbjct: 399  GRFSVSPRGQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDG----LPPVIL 454

Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEA 4576
                N  +  G  V L  +VTG     V W K+G+ +Q  D++ K +      TL I   
Sbjct: 455  QGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANG---TLYIANV 511

Query: 4577 YPQDSGKYECVAINSAGEA 4595
               D G Y CVA +S GEA
Sbjct: 512  QEMDMGFYSCVAKSSTGEA 530



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 46/184 (25%), Positives = 72/184 (39%), Gaps = 7/184 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL----VNESGN 447
           PQ V   QD+    G+   F C   G P P + W     Q+    +  +      + S  
Sbjct: 347 PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE-QVVAPKFVERFSTLNVREGE 506
             L IT V   D+G   C A + +G    +  L +       + P  ++  +   +  G 
Sbjct: 407 GQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGS 466

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            V L  R  G P P + W+KDG   +   +L+  T     TL I   +  D  +Y C A+
Sbjct: 467 SVWLPCRVTGNPQPSVRWKKDG-QWLQGDDLQFKTMAN-GTLYIANVQEMDMGFYSCVAK 524

Query: 567 NVAG 570
           +  G
Sbjct: 525 SSTG 528



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 6/110 (5%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E +V   P F+ +  +  V     V F C V  K DP  R+ W +    LP+G RY    
Sbjct: 251  EVMVLERPSFLRRPVNQVVLADAPVTFLCEV--KGDPPPRLRWRKEDGELPTG-RYEIRS 307

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            D    SL I +V AED G Y C A N  G      ++S    P ++ Q Q
Sbjct: 308  DH---SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQ 354



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 33/84 (39%), Positives = 43/84 (51%), Gaps = 7/84 (8%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            +N +V  +   + F C V+   DP  ++ W   +  LP+G RY+   D S   L I H  
Sbjct: 265  VNQVVLADAP-VTFLCEVKG--DPPPRLRWRKEDGELPTG-RYEIRSDHS---LWIGHVS 317

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
             ED G YTC A NS G A  SGSL
Sbjct: 318  AEDEGTYTCVAENSVGRAEASGSL 341



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 16/117 (13%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK---LLPSGHRYRT-- 3880
            V  PP+ +TQ +       E V F+C  E K +P   I W + G    L PS     T  
Sbjct: 343  VHVPPQLVTQPQDQMAAPGESVAFQC--ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGR 400

Query: 3881 --VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK-----KLPDIILQ 3930
              V   G   L+I  V   D+G Y+C+AV+  G    KA +  K      LP +ILQ
Sbjct: 401  FSVSPRG--QLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDGLPPVILQ 455



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 6/97 (6%)

Query: 3712 PVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCR 3771
            PV F C V+  GDP  R+ W        TG R    +D    +L I ++ A D G YTC 
Sbjct: 274  PVTFLCEVK--GDPPPRLRWRKEDGELPTG-RYEIRSDH---SLWIGHVSAEDEGTYTCV 327

Query: 3772 ATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
            A N  G A  +  ++      +V + Q      GE +
Sbjct: 328  AENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESV 364



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 7/115 (6%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            EV V + P F+ +      L++     + C ++  P P +R  W      L +G RY   
Sbjct: 251  EVMVLERPSFLRRPVNQVVLADAPVT-FLCEVKGDPPPRLR--WRKEDGELPTG-RYEIR 306

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
            +D    +L I  V  ED G YTC A N++G+A +S  L+V     ++   Q + A
Sbjct: 307  SDH---SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMA 358



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 6/139 (4%)

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRL 1334
            +++ T    A   + +  + A   +    ++ V++ P F R   N   +    V   C +
Sbjct: 222  MMSHTLKSDAGMYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEV 281

Query: 1335 QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEA 1394
            +  GD   R+ W      + TG   R     D+ +L +  V  ED G YTC A N +G A
Sbjct: 282  K--GDPPPRLRWRKEDGELPTG---RYEIRSDH-SLWIGHVSAEDEGTYTCVAENSVGRA 335

Query: 1395 VTSCALRVIAKKDLILESQ 1413
              S +L V     L+ + Q
Sbjct: 336  EASGSLSVHVPPQLVTQPQ 354



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 13/104 (12%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASSR 684
           V+ PPQ +   +   A  G  + F+   E  G+P   I W K G        QS++ + R
Sbjct: 343 VHVPPQLVTQPQDQMAAPGESVAFQC--ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGR 400

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           F S+   G   L++ ++   D+G Y C+AVS  G    KA+L +
Sbjct: 401 F-SVSPRG--QLNITAVQRGDAGYYMCQAVSVAGSILAKALLEI 441



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/109 (30%), Positives = 47/109 (43%), Gaps = 6/109 (5%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E+P F +   N  V    PV     +    DP  R+ W      +  G R++   D  
Sbjct: 254  VLERPSFLRRPVNQVVLADAPVTFLCEVK--GDPPPRLRWRKEDGELPTG-RYEIRSDH- 309

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082
              +L I +  AED GTY C A N+VG A  + S+ V     L     D+
Sbjct: 310  --SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQ 356



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 7/140 (5%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G PP     P++  L   SS    CR+      S+R  W  +G+  L G  ++       
Sbjct: 448  GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVR--WKKDGQ-WLQGDDLQ-FKTMAN 503

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
              L I  V + D G Y+C A +  GEAT S  L+++   G+  +P        G  S   
Sbjct: 504  GTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPV 563

Query: 3675 LEETLHKREEITIEDEKPNP 3694
            + E    +  IT+   KPNP
Sbjct: 564  VTEI--TKNSITL-TWKPNP 580



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 14/103 (13%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGK----VLQSGHRYRTSNDFGFAALDILTVYG 1911
            +S G+ A   CR E  P PN  +EWY NG     V +    +R     G A      V+G
Sbjct: 75   VSRGEPATLPCRAEGRPRPN--IEWYKNGARVATVREDPRAHRLLLPSG-ALFFPRIVHG 131

Query: 1912 E----DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHES 1950
                 D G YTC A N LG A S    N   + +++RD   +S
Sbjct: 132  RRARPDEGVYTCVARNYLGAAASR---NASLEVAVLRDDFRQS 171



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 11/123 (8%)

Query: 1698 QRHSAQDEV-ITQAPVFTM-PMKDIRVAENQAAHF-EARLIPVGDPKLRVEWLRNGVPIE 1754
            +R SA  EV + + P F   P+  + +A+       E +    GDP  R+ W +    + 
Sbjct: 244  ERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVK----GDPPPRLRWRKEDGELP 299

Query: 1755 ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814
             + R     D    +L + +V+ ED GTYTC A N +G A  S +L V     L  + Q 
Sbjct: 300  -TGRYEIRSDH---SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQD 355

Query: 1815 ESA 1817
            + A
Sbjct: 356  QMA 358



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 13/132 (9%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D GTY+C A N  G+AE S  L     S    P+  T  Q+ +    G+S  F+C     
Sbjct: 320  DEGTYTCVAENSVGRAEASGSL-----SVHVPPQLVTQPQD-QMAAPGESVAFQCET--K 371

Query: 3177 DDPDMKIEWYHNGQP--MRHSTRIKTVSDFGFV---VLDIAYTQNHDSGEYVCRAYNKYG 3231
             +P   I W   G    +  S  ++    F       L+I   Q  D+G Y+C+A +  G
Sbjct: 372  GNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAVSVAG 431

Query: 3232 EDFTRATINCYG 3243
                +A +   G
Sbjct: 432  SILAKALLEIKG 443



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 6/65 (9%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           +++G+P P + W RK+   +   +Y +R      D SL I  +   DEG YTC A N  G
Sbjct: 280 EVKGDPPPRLRW-RKEDGELPTGRYEIR-----SDHSLWIGHVSAEDEGTYTCVAENSVG 333

Query: 154 EAICS 158
            A  S
Sbjct: 334 RAEAS 338



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 14/41 (34%), Positives = 23/41 (56%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
           P+I ++P +  +  G  A    +  G PRP + W+KNG R+
Sbjct: 64  PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARV 104



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF-NGKQITSANRIQT 1094
            EV + ++P FL   +  N++V    A      E + D    + W   +G+  T    I++
Sbjct: 251  EVMVLERPSFLR--RPVNQVVLAD-APVTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRS 307

Query: 1095 YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
             H     +L I  V AED G YT VA N+ G A+ S S++V     + T
Sbjct: 308  DH-----SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVT 351



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   P + ++  ++   F C +    D   R+ W      L TG R +  +D     L
Sbjct: 258  PSFLRRPVNQVVLADAPVTFLCEV--KGDPPPRLRWRKEDGELPTG-RYEIRSDHS---L 311

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             IG V   D G YTC A N  G A  S  L V     ++ +PQ
Sbjct: 312  WIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQ 354



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 270 QKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
           Q P N  +  G  A  + V   G+P P V+W K+G RL    + E   T     L + +T
Sbjct: 170 QSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARL---KEEEGRITIRGGKLMMSHT 226

Query: 329 QKSDSGHYTLLAENPNG 345
            KSD+G Y  +A N  G
Sbjct: 227 LKSDAGMYVCVASNMAG 243



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 6/70 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            G+ A  +C + P G P   V W ++  +L E+  RIT         + +SH    D G+Y
Sbjct: 180  GEPAVLEC-VPPRGHPEPSVSWRKDGARLKEEEGRITIRGG----KLMMSHTLKSDAGMY 234

Query: 2450 MCRASNLLGE 2459
            +C ASN+ GE
Sbjct: 235  VCVASNMAGE 244



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 42/157 (26%), Positives = 60/157 (38%), Gaps = 15/157 (9%)

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            ER     E    +RP FL    +   L +     F C V+   DP   + W     ++  
Sbjct: 244  ERESAAAEVMVLERPSFLRRPVNQVVLADAP-VTFLCEVK--GDPPPRLRWRKEDGELPT 300

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
            G RY    D    +L I +  AED GTY C A N +G A  + +L V     ++   Q  
Sbjct: 301  G-RYEIRSDH---SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQD- 355

Query: 2215 NGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGT 2251
                   Q+ A G S   + E     PP    +  G+
Sbjct: 356  -------QMAAPGESVAFQCETKGNPPPAIFWQKEGS 385



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/42 (42%), Positives = 23/42 (54%)

Query: 1645 EDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALP 1686
            ED GTYTC A N++G A  SG   VH    +  + Q + A P
Sbjct: 319  EDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAP 360



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 9/108 (8%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK-NGQPVTIGHRFRPIHDFGY 1501
            +P F+ RP + + V+    V F C+++   D   ++ W K +G+  T  +  R  H    
Sbjct: 257  RPSFLRRPVN-QVVLADAPVTFLCEVKG--DPPPRLRWRKEDGELPTGRYEIRSDH---- 309

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE 1549
             +L I  + AED G YTC A N VG  E S  L+      +V   Q++
Sbjct: 310  -SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQ 356



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 36/106 (33%), Positives = 46/106 (43%), Gaps = 11/106 (10%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT---GSRVHTL---N 3748
            PR  VE   ++ V  G P    CR E  G P   I+W+ NG   AT     R H L   +
Sbjct: 64   PRI-VEQPPDLLVSRGEPATLPCRAE--GRPRPNIEWYKNGARVATVREDPRAHRLLLPS 120

Query: 3749 DFGFIALDIDYIYAR-DAGEYTCRATNKWGSATT-TAKITCSAKRD 3792
               F    +    AR D G YTC A N  G+A +  A +  +  RD
Sbjct: 121  GALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRD 166



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 4/83 (4%)

Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261
            E  GDP  R+ W      +  G R++   D    +L I H ++ D G YT  A N +G A
Sbjct: 280  EVKGDPPPRLRWRKEDGELPTG-RYEIRSDH---SLWIGHVSAEDEGTYTCVAENSVGRA 335

Query: 1262 HTSAIVRVIERSDIVTDTQNEQA 1284
              S  + V     +VT  Q++ A
Sbjct: 336  EASGSLSVHVPPQLVTQPQDQMA 358



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 4/75 (5%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYT 2716
            G+   LE  V PR  P   + W K+G  L      + T   G + +S ++L++D +G+Y 
Sbjct: 180  GEPAVLEC-VPPRGHPEPSVSWRKDGARLKEEEG-RITIRGGKLMMS-HTLKSD-AGMYV 235

Query: 2717 CKATNLLGEAVSTAS 2731
            C A+N+ GE  S A+
Sbjct: 236  CVASNMAGERESAAA 250



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 6/65 (9%)

Query: 799 DPTMRVEWYK-DGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
           DP  R+ W K DG   T    I S       SL I H+ AED G+YT  A N +G A ++
Sbjct: 284 DPPPRLRWRKEDGELPTGRYEIRSDH-----SLWIGHVSAEDEGTYTCVAENSVGRAEAS 338

Query: 858 ASIRV 862
            S+ V
Sbjct: 339 GSLSV 343



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 34/126 (26%), Positives = 49/126 (38%), Gaps = 6/126 (4%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   +  D+G Y C+A +  G       LE    S    P         + L  G S 
Sbjct: 409  LNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSV 468

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMR-HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               C V    +P   + W  +GQ ++    + KT+++     L IA  Q  D G Y C A
Sbjct: 469  WLPCRVT--GNPQPSVRWKKDGQWLQGDDLQFKTMANG---TLYIANVQEMDMGFYSCVA 523

Query: 3227 YNKYGE 3232
             +  GE
Sbjct: 524  KSSTGE 529



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 4/68 (5%)

Query: 2667 EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            E + DP  ++ W K    L TG R +   D    +L I  +  +D G YTC A N +G A
Sbjct: 280  EVKGDPPPRLRWRKEDGELPTG-RYEIRSDH---SLWIGHVSAEDEGTYTCVAENSVGRA 335

Query: 2727 VSTASIKI 2734
             ++ S+ +
Sbjct: 336  EASGSLSV 343



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 15/38 (39%), Positives = 18/38 (47%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P  V  P  + V  GE A   CR  G P+P + W  NG
Sbjct: 64   PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNG 101



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 15/45 (33%), Positives = 26/45 (57%)

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
            +L I  V+  D G YTC A N++G+A  S +L++     ++ + Q
Sbjct: 310  SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQ 354



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 8/101 (7%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLL--HKNRFTPIYDFG 4029
            PP+ VTQ Q Q +    E+  F+C+    G+P   + W   G  +L        P   F 
Sbjct: 346  PPQLVTQPQDQMA-APGESVAFQCETK--GNPPPAIFWQKEGSQVLLFPSQSLQPTGRFS 402

Query: 4030 YVA---MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG 4067
                  +N   V   D+G Y+C+A ++ G    KA+++  G
Sbjct: 403  VSPRGQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKG 443



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 41/161 (25%), Positives = 67/161 (41%), Gaps = 21/161 (13%)

Query: 3082 IEWFYNGKTIEA------SHRIRTVYAFGMVVLEILGTKTT-DSGTYSCRATNKWGQA-- 3132
            IEW+ NG  +        +HR+            + G +   D G Y+C A N  G A  
Sbjct: 95   IEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARPDEGVYTCVARNYLGAAAS 154

Query: 3133 -EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
               S+++  +     Q P       N+  +  G+ A  EC V P   P+  + W  +G  
Sbjct: 155  RNASLEVAVLRDDFRQSPG------NVV-VAVGEPAVLEC-VPPRGHPEPSVSWRKDGAR 206

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            ++      T+   G +++  ++T   D+G YVC A N  GE
Sbjct: 207  LKEEEGRITIRG-GKLMM--SHTLKSDAGMYVCVASNMAGE 244



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/100 (25%), Positives = 38/100 (38%), Gaps = 7/100 (7%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP+  T P D + +   S  F+C      +    + W   G  +L            F +
Sbjct: 346  PPQLVTQPQDQMAAPGESVAFQCET--KGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSV 403

Query: 3617 -----LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
                 L I  V + DAG Y C+A +  G       L++KG
Sbjct: 404  SPRGQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKG 443



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+  Q   N     G +     ++ GNP P V W +K    ++ +    +      + +
Sbjct: 450 PPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRW-KKDGQWLQGDDLQFK---TMANGT 505

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L I  +   D G Y+C A++  GEA  S +++
Sbjct: 506 LYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 3/70 (4%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS-RYKLTYDGMYHFD 4168
            PPV +  P   T+  G      CRVTG+P+P V W  +G  +     ++K   +G  +  
Sbjct: 450  PPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLY-- 507

Query: 4169 IPKTRQYDTG 4178
            I   ++ D G
Sbjct: 508  IANVQEMDMG 517


>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
            heparan sulfate proteoglycan core protein precursor
            protein.
          Length = 2331

 Score = 96.7 bits (230), Expect = 2e-18
 Identities = 104/424 (24%), Positives = 174/424 (41%), Gaps = 48/424 (11%)

Query: 4394 AQTQERVV--EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI 4451
            AQ Q  V+   G + P  P +  ++ +   V     A       G P P I W +   P+
Sbjct: 1134 AQKQVEVIVDTGAMAPGAPQVQAEEAE-LTVEAGHTATLRCSATGSPAPTIHWSKLRSPL 1192

Query: 4452 KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGI 4511
                  +  T      LII +V  +DS  +   A +  G A+ +  L VE          
Sbjct: 1193 PWQYRLEGDT------LIIPRVAQQDSGQYICNATSPAGHAEATIILHVES--------- 1237

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
             PP  T   ++ +V +G+ V+L     GT P+   W + G  +  +   RN++L  +   
Sbjct: 1238 -PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFE--- 1293

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP- 4628
                  A P+DSG+Y C   N  G A   A+ +V  P     P     A + P   + P 
Sbjct: 1294 -----RAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP-PGSLPATSIPAGSTPTVQVTPQ 1347

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L+ K +  G ++EF C +       ++W+K    + P        +  +  LRI      
Sbjct: 1348 LETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP------GHSVQDGVLRIQNLDQS 1399

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             +G Y C A+   G+   +A+L V Q   +  +   T ++ +VV  G   +F+       
Sbjct: 1400 CQGTYICQAHGPWGKAQASAQL-VIQALPSVLINIRTSVQTVVV--GHAVEFECLALGDP 1456

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            KP + W + G  +   P   ++  G   V+ I +    D G + C AT AAG  ++   L
Sbjct: 1457 KPQVTWSKVGGHL--RPG--IVQSG--GVVRIAHVELADAGQYRCTATNAAGTTQSHVLL 1510

Query: 4809 VVKS 4812
            +V++
Sbjct: 1511 LVQA 1514



 Score = 84.2 bits (199), Expect = 1e-14
 Identities = 100/412 (24%), Positives = 148/412 (35%), Gaps = 43/412 (10%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIH 4460
            EG     + P+ +       V + + A F+        P+ ++W   N  ++++    +H
Sbjct: 953  EGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VH 1008

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                 SI+ I      +   +  VA N  G A+   NL V            PP+ ++  
Sbjct: 1009 ISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG----------PPTVSVLP 1058

Query: 4521 QN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            +  V V  G+ V L+    G       W +         +      D    L I  A P 
Sbjct: 1059 EGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPS 1118

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y C+A N+ G A+   E +V   A      PQ +A  A         +  V  G  
Sbjct: 1119 DAGTYVCLAQNALGTAQKQVEVIVDTGAMA-PGAPQVQAEEA---------ELTVEAGHT 1168

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
                C   G P PT+ W    KL  P  + Q     D  TL I     +D G Y C A +
Sbjct: 1169 ATLRCSATGSPAPTIHW---SKLRSPLPW-QYRLEGD--TLIIPRVAQQDSGQYICNATS 1222

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
             AG       L V  P  A  +P         V  G+  Q +         T QW R G+
Sbjct: 1223 PAGHAEATIILHVESPPYATTVP-----EHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 1277

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P            N +L       ED+G + CR T   G  E  A+L+V+
Sbjct: 1278 SLPGRA------TARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQ 1323



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 77/353 (21%), Positives = 148/353 (41%), Gaps = 32/353 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L + QV   DS  +        GT + S  + ++++        V     + + + ++
Sbjct: 426  SRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASL 485

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             +G  + L+  V    P  + W K G  +    R++I+       L I +  P DSG+Y 
Sbjct: 486  ANGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGS----RLRIPQVTPADSGEYV 539

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C   N AG    +   +V++  +     P      +PP  IE     +V EGQ ++ +C 
Sbjct: 540  CHVSNGAGSR--ETSLIVTIQGSGSSHVPSV----SPPIRIESSSPTVV-EGQTLDLNCV 592

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            +  +P   + WYK G  L  PS++    +T   + LR+ +    D G+Y C A N+   +
Sbjct: 593  VARQPQAIITWYKRGGSL--PSRH----QTHGSH-LRLHQMSVADSGEYVCRANNNIDAL 645

Query: 4705 TVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + V+    + + P  + P+R       V EG+       +  +    + W + G 
Sbjct: 646  EASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG 705

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +P        H+   + L + +    D+G + CR   ++G +E S  + +++
Sbjct: 706  SLPSH------HQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEA 752



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 90/356 (25%), Positives = 148/356 (41%), Gaps = 41/356 (11%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S+L + QV   DS  +        G  + S  + +E     G    +PP   + + +  V
Sbjct: 141  SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGP---IPP-VRIESSSSTV 196

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L   V G     V W K G  +    R+++        L I +A P D+G+Y 
Sbjct: 197  AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA--RHQVRGS----RLYIFQASPADAGQYV 250

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N       +A   V++  T+        A +  P  IEP   + VAEGQ ++ +C 
Sbjct: 251  CRASNGM-----EASITVTVTGTQGANLAYP-AGSTQPIRIEPSSSQ-VAEGQTLDLNCV 303

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            + G+    V W+K G  L  P ++           LR+ +A P D G+Y C    S+  V
Sbjct: 304  VPGQSHAQVTWHKRGGSL--PVRH-----QTHGSLLRLYQASPADSGEYVCRVLGSS--V 354

Query: 4705 TVAAKLKVTQPDQADNLPAL--TPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWLRE 4757
             + A + VT  + A ++PAL  TP   I      V EGQ       +  +    + W + 
Sbjct: 355  PLEASVLVTI-EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKR 413

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            G  +P        H+ + + L +      D+G + CR   ++G  E S  + ++ +
Sbjct: 414  GGSLPAR------HQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 463



 Score = 79.0 bits (186), Expect = 4e-13
 Identities = 95/410 (23%), Positives = 160/410 (39%), Gaps = 52/410 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP  T   +   V   E  + +    G P    +W R    +           +   +L 
Sbjct: 1238 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPG------RATARNELLH 1291

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP----PSFTLTAQNVNV 4525
              +   EDS  +     N+ G+A+  A L+V+          +P    P+  +T Q    
Sbjct: 1292 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 1351

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            + G  V     V   +   + W K G ++ P   + +  +DG   +  L+   Q  G Y 
Sbjct: 1352 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPG--HSV--QDGVLRIQNLDQSCQ--GTYI 1405

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI--VAEGQAIEFS 4643
            C A    G+A+  A+ V+                 A P ++  ++  +  V  G A+EF 
Sbjct: 1406 CQAHGPWGKAQASAQLVIQ----------------ALPSVLINIRTSVQTVVVGHAVEFE 1449

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C  +G P P V W K    ++P              +RI+     D G Y+C A N+AG 
Sbjct: 1450 CLALGDPKPQVTWSKVGGHLRP------GIVQSGGVVRIAHVELADAGQYRCTATNAAG- 1502

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             T +  L + Q      LP ++  +++ V  G  A F    +    P I W +    +P 
Sbjct: 1503 TTQSHVLLLVQA-----LPQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLP- 1556

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             PD ++     N +L++ +   +D GT+ C AT   G+V+  A L V  +
Sbjct: 1557 -PDSRL----ENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 1601



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 93/379 (24%), Positives = 152/379 (40%), Gaps = 44/379 (11%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            + WYR    +   P  Q+H     S L + QV   DS  +    EN  G  + S  + V 
Sbjct: 22   VTWYRRGGSLP--PHTQVHG----SRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVL 75

Query: 4502 EKRRQGRGGIVPPSFT----LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
                 G      P  T    +   + +V  GQ + L+  V G     V W K G  +   
Sbjct: 76   HGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA- 134

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
             R+   +  G+  L + +  P DSG+Y C  + ++G    +A  +V++ A+   P P   
Sbjct: 135  -RH---QTHGSL-LRLHQVTPADSGEYVCHVVGTSGPL--EASVLVTIEASVI-PGP--- 183

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
                PP  IE      VAEGQ ++ SC + G+    V WYK    +      + SR    
Sbjct: 184  ---IPPVRIES-SSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSR---- 235

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADNLPALTPLR----DIVV 4732
              L I +A P D G Y C A N     ++   +  TQ  + A    +  P+R       V
Sbjct: 236  --LYIFQASPADAGQYVCRASNGM-EASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQV 292

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
             EGQ       +  +    + W + G  +P      + H+ + ++L +      D+G + 
Sbjct: 293  AEGQTLDLNCVVPGQSHAQVTWHKRGGSLP------VRHQTHGSLLRLYQASPADSGEYV 346

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            CR   ++  +E S  + ++
Sbjct: 347  CRVLGSSVPLEASVLVTIE 365



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 74/305 (24%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V P+  + + +  V  GQ + L+  V G     V W K G  +    R+++    G+  L
Sbjct: 375  VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV---HGS-RL 428

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             +L+  P DSG+Y C  + S+G    +A  +V++   + +         A P  IE    
Sbjct: 429  RLLQVTPADSGEYVCRVVGSSGTQ--EASVLVTI---QQRLSGSHSQGVAYPVRIES-SS 482

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
              +A G  ++ +C +  +   T+ WYK G  L  PS++  +        LRI +  P D 
Sbjct: 483  ASLANGHTLDLNCLVASQAPHTITWYKRGGSL--PSRHQIVGS-----RLRIPQVTPADS 535

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQIT 4745
            G+Y C   N AG    +  + + Q   + ++P+++P   I      V EGQ       + 
Sbjct: 536  GEYVCHVSNGAGSRETSLIVTI-QGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVA 594

Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             + +  I W + G  +P        H+ + + L +      D+G + CRA      +E S
Sbjct: 595  RQPQAIITWYKRGGSLPSR------HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEAS 648

Query: 4806 AKLVV 4810
              + V
Sbjct: 649  IVISV 653



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 71/280 (25%), Positives = 116/280 (41%), Gaps = 33/280 (11%)

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            +VT GQ + L+  V G+    V W + G  + P       +  G+  L + +  P DSG+
Sbjct: 1    SVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPH-----TQVHGS-RLRLPQVSPADSGE 54

Query: 4584 YECVAINSAGEARCDAECVVS-LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
            Y C   N +G    +A   VS L  T   P       +  P  IEP     VAEGQ ++ 
Sbjct: 55   YVCRVENGSGPK--EASITVSVLHGTHSGPSYTPVPGSTRPIRIEP-SSSHVAEGQTLDL 111

Query: 4643 SCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            +C + G+    V W+K G  L  P+++           LR+ +  P D G+Y C    ++
Sbjct: 112  NCVVPGQAHAQVTWHKRGGSL--PARH-----QTHGSLLRLHQVTPADSGEYVCHVVGTS 164

Query: 4702 GRVTVAAKLKVTQPDQADNLPA-LTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
            G +  +  + +    +A  +P  + P+R       V EGQ       +  +    + W +
Sbjct: 165  GPLEASVLVTI----EASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYK 220

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             G  +P        H+   + L I      D G + CRA+
Sbjct: 221  RGGSLPAR------HQVRGSRLYIFQASPADAGQYVCRAS 254



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 79/354 (22%), Positives = 146/354 (41%), Gaps = 33/354 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L I QV   DS  +     N  G+ + S  + ++         + PP   + + +  V
Sbjct: 523  SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPP-IRIESSSPTV 581

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L+  V       + W K G  +    R+   +  G++ L + +    DSG+Y 
Sbjct: 582  VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RH---QTHGSH-LRLHQMSVADSGEYV 635

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N+      +A  V+S+  +   P   +   ++ P  IE      VAEG+ ++ +C 
Sbjct: 636  CRANNNIDAL--EASIVISVSPSAGSP---SAPGSSMPIRIESSSSH-VAEGETLDLNCV 689

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            + G+    V W+K    +      + SR      LR+    P D G+Y C    S+G + 
Sbjct: 690  VPGQAHAQVTWHKRGGSLPSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLE 743

Query: 4706 VAAKLKV-TQPDQADNLPA---LTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
             +  + +      A ++PA     P+R       V EGQ    K  +  +    + W + 
Sbjct: 744  ASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKR 803

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G  +P        H+ +  +L +      D+G ++C+ T ++G +E S  + ++
Sbjct: 804  GGNLPAR------HQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIE 851



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 87/362 (24%), Positives = 140/362 (38%), Gaps = 34/362 (9%)

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP---PSF 4516
            H  +  S L +  V   DS  +        G  + S  + +E           P   P  
Sbjct: 710  HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPI 769

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
             +   +  V  GQ + L   V G     V W K G  +    R+++    G   L + + 
Sbjct: 770  RIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPA--RHQV---HGPL-LRLNQV 823

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
             P DSG+Y C    S+G    +A  +V++  +   P P    A   P  IE      V E
Sbjct: 824  SPADSGEYSCQVTGSSGTL--EASVLVTIEPSSPGPIPAPGLAQ--PIYIEASSSH-VTE 878

Query: 4637 GQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            GQ ++ +C + G+    V WYK G  L  P+++           LR+    P D G+Y C
Sbjct: 879  GQTLDLNCVVPGQAHAQVTWYKRGGSL--PARH-----QTHGSQLRLHLVSPADSGEYVC 931

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQITSKIKP 4750
             A +  G    A+      P +  +    +P+  I      V +GQ A FK  I     P
Sbjct: 932  RAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAP 991

Query: 4751 -TIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +++W      + +      +H   N +++ I  T   + GT+ C A+ A G  ++   L
Sbjct: 992  ISLEWKTRNQELEDN-----VHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNL 1046

Query: 4809 VV 4810
             V
Sbjct: 1047 SV 1048



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 30/292 (10%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V  GQ + L+  V G     V W K G  +   +R+   +  G+  L + +A P DSG+Y
Sbjct: 292  VAEGQTLDLNCVVPGQSHAQVTWHKRGGSLP--VRH---QTHGSL-LRLYQASPADSGEY 345

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C  + S+     +A  +V++     +P     A    P +        VAEGQ ++ +C
Sbjct: 346  VCRVLGSS--VPLEASVLVTI-----EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNC 398

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             + G+    V W+K    +        SR      LR+ +  P D G+Y C    S+G  
Sbjct: 399  LVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSGEYVCRVVGSSGTQ 452

Query: 4705 TVAAKLKVTQ-----PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + + Q       Q    P         +  G        + S+   TI W + G 
Sbjct: 453  EASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGG 512

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P        H+   + L I      D+G + C  +  AG  ETS  + ++
Sbjct: 513  SLPSR------HQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 558



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 113/531 (21%), Positives = 182/531 (34%), Gaps = 67/531 (12%)

Query: 52   VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
            +E+SG    +    PG   P   E    ++R A+G     +  + G     V+W ++   
Sbjct: 750  IEASGS-SAVHVPAPGGAPPIRIEP--SSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGN 806

Query: 112  LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXX 171
            L            Q     L + Q+ P D GEY+C      G    SV +  E       
Sbjct: 807  LPA--------RHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPI 858

Query: 172  XXXXXXXYRHVSETVEHKAYGTQ---GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEY 228
                     ++  +  H   G               Q   Y  G    +           
Sbjct: 859  PAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRL 918

Query: 229  RLLREVSFRESITKRYVG---ESDVQISTEIDRSLGP---VSPPKIAQKPRNSKLQEGAD 282
             L+      E + +   G   E +   +  +  S G    +  P I+  P +S +Q+G D
Sbjct: 919  HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQD 978

Query: 283  AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            A F+  +     P    +K   + +  N H    + N + + +  T+ S+ G Y      
Sbjct: 979  ASFKCLIHDGAAPISLEWKTRNQELEDNVH---ISPNGSIITIVGTRPSNHGTYR----- 1030

Query: 343  PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
               C+ ++ Y   +S     V    +                +S     P +VKV     
Sbjct: 1031 ---CVASNAYGVAQSVVNLSVHGPPT----------------VSVLPEGPVWVKV----- 1066

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHA-LMITNVTLSDS 460
               GK    +C   G P     W  I+    + +     L++   +HA L I++   SD+
Sbjct: 1067 ---GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMD---SHAVLQISSAKPSDA 1120

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
            G   C+A+N  G    Q  + V        AP+     + L V  G    L   A G+P 
Sbjct: 1121 GTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPA 1180

Query: 520  PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P I W K   P+    + R+  D    TL IPR    D+  Y C A + AG
Sbjct: 1181 PTIHWSKLRSPL--PWQYRLEGD----TLIIPRVAQQDSGQYICNATSPAG 1225



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 56/177 (31%), Positives = 74/177 (41%), Gaps = 21/177 (11%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G    F+C   G P P+VTW      +R       +V   G   + I +V L+D+G 
Sbjct: 1440 VVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG-----IVQSGG--VVRIAHVELADAGQ 1492

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A N +G T     L V    Q+  P+ V       V  G   V    A G PTP I
Sbjct: 1493 YRCTATNAAGTTQSHVLLLVQALPQISMPQEV------RVPAGSAAVFPCIASGYPTPDI 1546

Query: 523  TWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +W K DG   +P P+ R+      + L +P  +  DA  Y CTA N  G     A L
Sbjct: 1547 SWSKLDG--SLP-PDSRLEN----NMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHL 1596



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 80/315 (25%), Positives = 109/315 (34%), Gaps = 41/315 (13%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP     P ++ +Q G   Q Q    G P     W + G  L          T  +  L
Sbjct: 1237 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGR------ATARNELL 1290

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG Y     N  G       L V+ P  S          T T Q       
Sbjct: 1291 HFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ------- 1343

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
                  + PQ     + + +  G    F C V      ++ WF    Q+     H +   
Sbjct: 1344 ------VTPQL----ETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP--GHSV--- 1386

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            + G   L I N+  S  G   C A    G+     +L VI+    V      R S   V 
Sbjct: 1387 QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQASAQL-VIQALPSVLINI--RTSVQTVV 1441

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             G  V     A+G P P++TW K G  + P     I   GG   + I   + +DA  Y+C
Sbjct: 1442 VGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGG--VVRIAHVELADAGQYRC 1495

Query: 564  TAQNVAGSTATRARL 578
            TA N AG+T +   L
Sbjct: 1496 TATNAAGTTQSHVLL 1510



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 42/188 (22%), Positives = 74/188 (39%), Gaps = 21/188 (11%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V EGQ ++ +C + G     V WY+    + P      SR      LR+ +  P D G+Y
Sbjct: 2    VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSR------LRLPQVSPADSGEY 55

Query: 4694 KCVAYNSAG----RVTVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQI 4744
             C   N +G     +TV+             +P  T P+R       V EGQ       +
Sbjct: 56   VCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVV 115

Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
              +    + W + G  +P        H+ + ++L +      D+G + C     +G +E 
Sbjct: 116  PGQAHAQVTWHKRGGSLPAR------HQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEA 169

Query: 4805 SAKLVVKS 4812
            S  + +++
Sbjct: 170  SVLVTIEA 177



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 115/528 (21%), Positives = 187/528 (35%), Gaps = 68/528 (12%)

Query: 62   TAGRPGEPSPPIFEQI-FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            +AG P  P   +  +I   ++  A+G        + G     V+W ++          S+
Sbjct: 656  SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG--------SL 707

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXX 178
              + QT    L +  + P D GEY C      G  EA   V I+  G             
Sbjct: 708  PSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAP 767

Query: 179  YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV-DTFEYRLLR--EVS 235
               +  +    A   +G T +        A+   T H    +          LLR  +VS
Sbjct: 768  PIRIEPSSSRVA---EGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVS 824

Query: 236  FRES--ITKRYVGES---DVQISTEIDRSL-GPVSPPKIAQ----KPRNSKLQEGADAQF 285
              +S   + +  G S   +  +   I+ S  GP+  P +AQ    +  +S + EG     
Sbjct: 825  PADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 884

Query: 286  QVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               + G    +VTW+K G  L    +H+   TH  + LR+     +DSG Y   A +  G
Sbjct: 885  NCVVPGQAHAQVTWYKRGGSL--PARHQ---THG-SQLRLHLVSPADSGEYVCRAASGPG 938

Query: 346  CIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTE 405
                + +     P+E      RS  I+      T                       V +
Sbjct: 939  PEQEASFTVTVPPSEGSSYRLRSPVISIDPPSST-----------------------VQQ 975

Query: 406  GKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
            G+   F C +     P  + W   ++++ D+ +    ++ +G+  + I     S+ G   
Sbjct: 976  GQDASFKCLIHDGAAPISLEWKTRNQELEDNVH----ISPNGS-IITIVGTRPSNHGTYR 1030

Query: 465  CVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
            CVA N  G       L+V     V V P+       + V+ G+ V L   + G P     
Sbjct: 1031 CVASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVWVKVGKAVTLECVSAGEPRSSAR 1085

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            W +         +         + L I  AK SDA  Y C AQN  G+
Sbjct: 1086 WTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGT 1133



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 53/231 (22%), Positives = 82/231 (35%), Gaps = 20/231 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H++          L +L     DSG
Sbjct: 388  VAEGQTL--DLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSG 439

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CR     G  E SV +    +  G   +   +   IE     L +G +    C V  
Sbjct: 440  EYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVA- 498

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
                   I WY  G  +   +R + V       L I      DSGEYVC   N  G   T
Sbjct: 499  -SQAPHTITWYKRGGSL--PSRHQIVGSR----LRIPQVTPADSGEYVCHVSNGAGSRET 551

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
               +   G G  ++ S+ P    +      ++G         + +P   IT
Sbjct: 552  SLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIIT 602



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 14/173 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + +GQ A ++  LI  G   + +EW    + +E +  I    +    ++ I+GT+ ++ G
Sbjct: 973  VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHG 1027

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
            TY C A+N +G A+  V L     S    P  +   +    +K G++   EC  V   +P
Sbjct: 1028 TYRCVASNAYGVAQSVVNL-----SVHGPPTVSVLPEGPVWVKVGKAVTLEC--VSAGEP 1080

Query: 3180 DMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                 W   +  P +   R   + D    VL I+  +  D+G YVC A N  G
Sbjct: 1081 RSSARWTRISSTPAKLEQRTYGLMD-SHAVLQISSAKPSDAGTYVCLAQNALG 1132



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 80/320 (25%), Positives = 123/320 (38%), Gaps = 52/320 (16%)

Query: 261 GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
           G   P +I  +P +S++ EG        + G    +VTW K G  L    +H+   TH  
Sbjct: 278 GSTQPIRI--EPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSL--PVRHQ---THG- 329

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
           + LR+     +DSG Y       +  +  S  + +E P  S      +  +T T      
Sbjct: 330 SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVP----ALGVTPTV----- 379

Query: 381 ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            RIE S   +A             EG+    +C V G+ + +VTW      +     H++
Sbjct: 380 -RIESSSSQVA-------------EGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV 423

Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGE------TAFQCRLNVIEKEQVVAPKFV 494
                G+  L +  VT +DSG   C     SG          Q RL+    + V  P  +
Sbjct: 424 ----HGSR-LRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRI 478

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
           E  S+ ++  G  + LN          ITW K G  +    ++        S L IP+  
Sbjct: 479 ES-SSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI------VGSRLRIPQVT 531

Query: 555 ASDAAWYQCTAQNVAGSTAT 574
            +D+  Y C   N AGS  T
Sbjct: 532 PADSGEYVCHVSNGAGSRET 551



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 59/278 (21%), Positives = 106/278 (38%), Gaps = 24/278 (8%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A       G+P P + W++ ++PL        +Y  + GD +L+I ++   D G+Y 
Sbjct: 1166 GHTATLRCSATGSPAPTIHWSKLRSPL------PWQYRLE-GD-TLIIPRVAQQDSGQYI 1217

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQ 205
            C A +  G A  ++ +  E                  +  ++  A+GT   T + SR   
Sbjct: 1218 CNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGS 1277

Query: 206  KVAYTNGTDHSSTDDFK----VDTFEY--RLLREVSFRESITKRYVGESDVQISTEIDRS 259
             +     T  +    F+     D+  Y  R+  +V   E+  +  V      +      S
Sbjct: 1278 SLP-GRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPA---TS 1333

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            +   S P +   P+      GA  +F   +  +   ++ WFK G +L     H +     
Sbjct: 1334 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQL--PPGHSV----Q 1387

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
               LR++N  +S  G Y   A  P G    S  L +++
Sbjct: 1388 DGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQA 1425



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 60/246 (24%), Positives = 95/246 (38%), Gaps = 42/246 (17%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E TI     +PP +   + ++  V  G  V   C     G P +   W   G       R
Sbjct: 1228 EATIILHVESPP-YATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLP--GR 1282

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
                N+     L  +     D+G Y CR TNK GSA   A++        +  + +P G 
Sbjct: 1283 ATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGS 1338

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            +                   P V   P    Q+++ ++  S  V F C V      +LR 
Sbjct: 1339 T-------------------PTVQVTP----QLETKSIGAS--VEFHCAVPSDRGTQLR- 1372

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             W++ G  LP GH   +V D G + +  L    +  G YIC+A   +G+    A +  + 
Sbjct: 1373 -WFKEGGQLPPGH---SVQD-GVLRIQNLDQSCQ--GTYICQAHGPWGKAQASAQLVIQA 1425

Query: 3924 LPDIIL 3929
            LP +++
Sbjct: 1426 LPSVLI 1431



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 18/155 (11%)

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
            D+   + WF  G  +   H ++        VL I     +  GTY C+A   WG+A+ S 
Sbjct: 1366 DRGTQLRWFKEGGQLPPGHSVQDG------VLRIQNLDQSCQGTYICQAHGPWGKAQASA 1419

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +L  +           T +Q +     G +  FEC  + + DP  ++ W   G  +R   
Sbjct: 1420 QL-VIQALPSVLINIRTSVQTV---VVGHAVEFEC--LALGDPKPQVTWSKVGGHLRPG- 1472

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                V   G  V+ IA+ +  D+G+Y C A N  G
Sbjct: 1473 ---IVQSGG--VVRIAHVELADAGQYRCTATNAAG 1502



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 56/240 (23%), Positives = 91/240 (37%), Gaps = 44/240 (18%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            ++P +   +    +++ GE    +     T  P L  +W   G SL   +  R       
Sbjct: 1236 ESPPYATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARN------ 1287

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537
             +L      PEDSG Y CR  N  G A   A + VQG    +  + +P G   T+     
Sbjct: 1288 ELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ---- 1343

Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
                      +TP+ E+               S  +S  F C  +P +D   ++ WF  G
Sbjct: 1344 ----------VTPQLET--------------KSIGASVEFHC-AVP-SDRGTQLRWFKEG 1377

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
              L  G  V+        +L I  + Q   G Y C+A    G+A  S +L ++    +++
Sbjct: 1378 GQLPPGHSVQD------GVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLI 1431



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 72/291 (24%), Positives = 109/291 (37%), Gaps = 41/291 (14%)

Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
           EG        ++G+   +VTW++ G  L     H   T  + + LR+     +DSG Y  
Sbjct: 4   EGQTLDLNCVVAGSAHAQVTWYRRGGSL---PPH---TQVHGSRLRLPQVSPADSGEYVC 57

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             EN +G    S  ++V   T S          T         RIE S   +A       
Sbjct: 58  RVENGSGPKEASITVSVLHGTHS------GPSYTPVPGSTRPIRIEPSSSHVA------- 104

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
                 EG+    +C V G+ + +VTW      +   +       ++    L +  VT +
Sbjct: 105 ------EGQTLDLNCVVPGQAHAQVTWHKRGGSLPARH-------QTHGSLLRLHQVTPA 151

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--STLNVREGEPVVLNARAVG 516
           DSG   C     SG       L  IE   +  P    R   S+  V EG+ + L+    G
Sbjct: 152 DSGEYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAG 210

Query: 517 TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
               ++TW K G  +    ++R       S L I +A  +DA  Y C A N
Sbjct: 211 QAHAQVTWYKRGGSLPARHQVR------GSRLYIFQASPADAGQYVCRASN 255



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + S +  G     + W+  G ++ A H++R    +      I      D+G
Sbjct: 196  VAEGQTL--DLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLY------IFQASPADAG 247

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CRA+N   +A I+V +     +    P  +T    IE     + +GQ+    C VVP
Sbjct: 248  QYVCRASNGM-EASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC-VVP 305

Query: 3176 VDDPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                  ++ W+  G   P+RH T           +L +      DSGEYVCR
Sbjct: 306  -GQSHAQVTWHKRGGSLPVRHQTHGS--------LLRLYQASPADSGEYVCR 348



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 25/181 (13%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    +  ++P G     + W   G  + A H++         +L +      DSG
Sbjct: 778  VAEGQTLDLKC-VVP-GQAHAQVTWHKRGGNLPARHQVHGP------LLRLNQVSPADSG 829

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKP----RFTTHIQ-NIEGLKDGQSAHFECTVV 3174
             YSC+ T   G  E SV +     S G  P        +I+ +   + +GQ+    C VV
Sbjct: 830  EYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VV 888

Query: 3175 PVDDPDMKIEWYHNG--QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P      ++ WY  G   P RH T            L +      DSGEYVCRA +  G 
Sbjct: 889  P-GQAHAQVTWYKRGGSLPARHQTHGSQ--------LRLHLVSPADSGEYVCRAASGPGP 939

Query: 3233 D 3233
            +
Sbjct: 940  E 940



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 17/188 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W+  G ++ A H+           L +      DSG
Sbjct: 876  VTEGQTL--DLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQ------LRLHLVSPADSG 927

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE----GLKDGQSAHFECTVVP 3175
             Y CRA +  G  + +     V  S+G   R  + + +I+     ++ GQ A F+C +  
Sbjct: 928  EYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHD 987

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               P + +EW    Q +  +  I         ++ I  T+  + G Y C A N YG   +
Sbjct: 988  GAAP-ISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHGTYRCVASNAYGVAQS 1042

Query: 3236 RATINCYG 3243
               ++ +G
Sbjct: 1043 VVNLSVHG 1050



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 93/458 (20%), Positives = 160/458 (34%), Gaps = 60/458 (13%)

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP-EGXXXXXXXXXXXXXYRHVSETVEHK 189
           L + Q+ P D GEY C   N  G    S+ +    G              R +       
Sbjct: 42  LRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPI-RIEPSS 100

Query: 190 AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEY-RLLREVSFRESITKRYV--- 245
           ++  +G T + +      A+   T H            +  LLR      + +  YV   
Sbjct: 101 SHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHV 160

Query: 246 ----GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
               G  +  +   I+ S+ P   P +  +  +S + EG        ++G    +VTW+K
Sbjct: 161 VGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYK 220

Query: 302 NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTES 361
            G  L    +H++      + L +     +D+G Y         C  ++G  A  + T +
Sbjct: 221 RGGSL--PARHQV----RGSRLYIFQASPADAGQYV--------CRASNGMEASITVTVT 266

Query: 362 YVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYP 421
             Q     Y   + Q     RIE S                V EG+    +C V G+ + 
Sbjct: 267 GTQGANLAYPAGSTQ---PIRIEPSSS-------------QVAEGQTLDLNCVVPGQSHA 310

Query: 422 EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
           +VTW      +        + +++    L +   + +DSG   C     S        + 
Sbjct: 311 QVTWHKRGGSLP-------VRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVT 363

Query: 482 VIEKEQV----VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
           +     V    V P      S+  V EG+ + LN    G    ++TW K G  +    + 
Sbjct: 364 IEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQ- 422

Query: 538 RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
            +H     S L + +   +D+  Y C    V GS+ T+
Sbjct: 423 -VH----GSRLRLLQVTPADSGEYVC---RVVGSSGTQ 452



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/306 (24%), Positives = 118/306 (38%), Gaps = 46/306 (15%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P +  +  +S++ EG        ++G    +VTW K G  L    +H++    + + LR+
Sbjct: 377 PTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV----HGSRLRL 430

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
                +DSG Y         C V       E+     +Q + S   + +Q      RIE 
Sbjct: 431 LQVTPADSGEYV--------CRVVGSSGTQEASVLVTIQQRLSG--SHSQGVAYPVRIES 480

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
           S  +LA              G     +C V  +    +TW+     +     H+I+ +  
Sbjct: 481 SSASLA-------------NGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGSR- 524

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQV--VAPKFVERFSTLN 501
               L I  VT +DSG   C   N +G  ET+    +       V  V+P      S+  
Sbjct: 525 ----LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPT 580

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           V EG+ + LN      P   ITW K G   +P+   R  T G  S L + +   +D+  Y
Sbjct: 581 VVEGQTLDLNCVVARQPQAIITWYKRG-GSLPS---RHQTHG--SHLRLHQMSVADSGEY 634

Query: 562 QCTAQN 567
            C A N
Sbjct: 635 VCRANN 640



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 8/108 (7%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            + P + T +    S+   ET + +C LA  G P +  +W   G  L    R T   +   
Sbjct: 1236 ESPPYATTVPEHASVQAGETVQLQC-LAH-GTPPLTFQWSRVGSSL--PGRATARNEL-- 1289

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP 4078
              ++F    PEDSG Y CR TN  G  E  A +   G PG +  + +P
Sbjct: 1290 --LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIP 1335



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 54/212 (25%), Positives = 76/212 (35%), Gaps = 19/212 (8%)

Query: 368  SQYITDTQQRETEERIEISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
            +Q    T Q++ E  ++    A  APQ      +  V  G      C  TG P P + W 
Sbjct: 1127 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW- 1185

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
                ++R     +  +       L+I  V   DSG   C A + +G       L+V  + 
Sbjct: 1186 ---SKLRSPLPWQYRLE---GDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHV--ES 1237

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
               A    E  S   V+ GE V L   A GTP     W + G  +      R        
Sbjct: 1238 PPYATTVPEHAS---VQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR------NE 1288

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             L   RA   D+  Y+C   N  GS    A+L
Sbjct: 1289 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQL 1320



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 46/153 (30%), Positives = 61/153 (39%), Gaps = 23/153 (15%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+  G ++ + H+I      G   L I      DSG Y C  +N  G  E S+ +   
Sbjct: 505  ITWYKRGGSLPSRHQI-----VGSR-LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 558

Query: 3142 DKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQ--PMRHS 3195
                   P  +  I+ IE     + +GQ+    C V     P   I WY  G   P RH 
Sbjct: 559  GSGSSHVPSVSPPIR-IESSSPTVVEGQTLDLNCVVAR--QPQAIITWYKRGGSLPSRHQ 615

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            T     S      + +A     DSGEYVCRA N
Sbjct: 616  TH---GSHLRLHQMSVA-----DSGEYVCRANN 640



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 29/218 (13%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            +I W+  G ++ + H+    +      L +      DSG Y CRA N     E S+ +  
Sbjct: 600  IITWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVIS- 652

Query: 3141 VDKSKG--QKPRFTTHIQ---NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG--QPMR 3193
            V  S G    P  +  I+   +   + +G++    C VVP      ++ W+  G   P  
Sbjct: 653  VSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC-VVP-GQAHAQVTWHKRGGSLPSH 710

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATINCYGKGGVYLES 3251
            H TR           L + +    DSGEYVCR     G  E     TI   G   V++ +
Sbjct: 711  HQTRGSR--------LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPA 762

Query: 3252 LQPDSLAKIR-ELESLQGAQQQTPSTPSAEPPKFITQI 3288
              P     IR E  S + A+ QT       P +   Q+
Sbjct: 763  --PGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQV 798



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQ 3165
            VL+I   K +D+GTY C A N  G A+  V++  VD             +  E  ++ G 
Sbjct: 1109 VLQISSAKPSDAGTYVCLAQNALGTAQKQVEV-IVDTGAMAPGAPQVQAEEAELTVEAGH 1167

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A   C+      P   I W     P+    R++   D     L I      DSG+Y+C 
Sbjct: 1168 TATLRCSA--TGSPAPTIHWSKLRSPLPWQYRLE--GD----TLIIPRVAQQDSGQYICN 1219

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
            A +  G     ATI  + +   Y  ++   +  +  E   LQ     TP
Sbjct: 1220 ATSPAGH--AEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTP 1266



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 12/117 (10%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            T+  + +  +AL PQ + + Q+  V  G    F C  +G P P+++W   D  +  D   
Sbjct: 1504 TQSHVLLLVQAL-PQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPD--- 1558

Query: 439  KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
                +   N+ LM+ +V   D+G   C A N+ G+      L V E+   V P F +
Sbjct: 1559 ----SRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER---VVPYFTQ 1608



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 55/218 (25%), Positives = 79/218 (36%), Gaps = 27/218 (12%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H+          +L +      DSG
Sbjct: 103  VAEGQTL--DLNCVVPGQAHAQVTWHKRGGSLPARHQTHGS------LLRLHQVTPADSG 154

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDD 3178
             Y C      G  E SV L  ++ S    P     I++    + +GQ+    C V     
Sbjct: 155  EYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA--GQ 211

Query: 3179 PDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
               ++ WY  G   P RH  R           L I      D+G+YVCRA N      T 
Sbjct: 212  AHAQVTWYKRGGSLPARHQVRGSR--------LYIFQASPADAGQYVCRASNGMEASITV 263

Query: 3237 ATINCYGKGGVY-LESLQPDSLAKIRELESLQGAQQQT 3273
                  G    Y   S QP  +    E  S Q A+ QT
Sbjct: 264  TVTGTQGANLAYPAGSTQPIRI----EPSSSQVAEGQT 297



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 62/267 (23%), Positives = 97/267 (36%), Gaps = 46/267 (17%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            DSG Y C AT+  G AE ++ L        + P + T +     ++ G++   +C  +  
Sbjct: 1212 DSGQYICNATSPAGHAEATIILHV------ESPPYATTVPEHASVQAGETVQLQC--LAH 1263

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P +  +W   G  +      +        +L        DSG Y CR  NK G     
Sbjct: 1264 GTPPLTFQWSRVGSSLPGRATARNE------LLHFERAAPEDSGRYRCRVTNKVGSAEAF 1317

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +   G  G                  SL        STP+ +    +T  Q  TK + 
Sbjct: 1318 AQLLVQGPPG------------------SLPATSIPAGSTPTVQ----VTP-QLETKSI- 1353

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356
            G S  F    VP  D   ++ WF  G +LP GH  +        +L I    +   G Y 
Sbjct: 1354 GASVEFHC-AVP-SDRGTQLRWFKEGGQLPPGHSVQD------GVLRIQNLDQSCQGTYI 1405

Query: 3357 CVATNKLGRDSTKANLKCTSKENLILD 3383
            C A    G+    A L   +  +++++
Sbjct: 1406 CQAHGPWGKAQASAQLVIQALPSVLIN 1432



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            + S  P    +  S TV E + +   C V     P+  I WY+ G  LPS H+    +  
Sbjct: 565  VPSVSPPIRIESSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH-- 620

Query: 3885 GFVSLDILYVYAEDSGEYICRAVND 3909
                L +  +   DSGEY+CRA N+
Sbjct: 621  ----LRLHQMSVADSGEYVCRANNN 641



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 55/239 (23%), Positives = 89/239 (37%), Gaps = 44/239 (18%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            +S   + EG      C V     P   I W+  G  + + H+   +H      L +    
Sbjct: 576  SSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH------LRLHQMS 627

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE 2235
              DSG Y+C+A N +           A   +I++      G        A G S  I +E
Sbjct: 628  VADSGEYVCRANNNID----------ALEASIVISVSPSAGSPS-----APGSSMPIRIE 672

Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295
                           ++HV EG+T    C V      + ++ ++  G +L S    H T 
Sbjct: 673  S-------------SSSHVAEGETLDLNCVVPG--QAHAQVTWHKRGGSLPS---HHQTR 714

Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  L + H  P D+GEY  + + + G   +++ +T+ A GS       P G   IR
Sbjct: 715  GS---RLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIR 770



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 56/276 (20%), Positives = 96/276 (34%), Gaps = 14/276 (5%)

Query: 85   QGGNAKFEGKLRGNPTPV-VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
            QG +A F+  +     P+ + W  +   L E N +        G + + I    P + G 
Sbjct: 975  QGQDASFKCLIHDGAAPISLEWKTRNQEL-EDNVHI----SPNGSI-ITIVGTRPSNHGT 1028

Query: 144  YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR-HVSETVEHKAYGTQGYTTEQSR 202
            Y C A N YG A   V +   G              +   + T+E  + G    +   +R
Sbjct: 1029 YRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTR 1088

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262
             +   A      +   D   V         +      + +  +G +  Q+   +D     
Sbjct: 1089 ISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMA 1148

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
               P++  +     ++ G  A  +   +G+P P + W K    L    + E        T
Sbjct: 1149 PGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQYRLE------GDT 1202

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L +    + DSG Y   A +P G    +  L VESP
Sbjct: 1203 LIIPRVAQQDSGQYICNATSPAGHAEATIILHVESP 1238



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR-NGVPIEASNRLTTMHDFGYVAL 1770
            V  +P   + V   +A   E   +  G+P+    W R +  P +   R   + D  +  L
Sbjct: 1054 VSVLPEGPVWVKVGKAVTLEC--VSAGEPRSSARWTRISSTPAKLEQRTYGLMD-SHAVL 1110

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +    P D+GTY C A N LG A     + V + A
Sbjct: 1111 QISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGA 1146



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q+GQ A F C LI  G   + +EW    + +ED+  I+         +TI   R  + G
Sbjct: 973  VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGSI----ITIVGTRPSNHG 1027

Query: 2448 VYMCRASNLLG 2458
             Y C ASN  G
Sbjct: 1028 TYRCVASNAYG 1038



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 38/178 (21%)

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            L + H      L +  V P DSG Y C   N  G   TS  + +Q        S H  ++
Sbjct: 514  LPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG-----SSHVPSV 568

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
                ++E SS                        PT + EGQ+    C +     P   +
Sbjct: 569  SPPIRIESSS------------------------PTVV-EGQTLDLNCVVAR--QPQAII 601

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             WY  G  L S H+   S+      L +  +   DSGEY C+A NN+    +SI ++V
Sbjct: 602  TWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVISV 653



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 12/122 (9%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI--RAGHRYRTTHDF 2164
            + P + T +    +++ G+    +C       P LT  W   G  +  RA  R    H F
Sbjct: 1236 ESPPYATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLPGRATARNELLH-F 1292

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
               A        EDSG Y C+ TNK+G A     L V G    +  T  P G     Q+ 
Sbjct: 1293 ERAA-------PEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 1345

Query: 2225 AQ 2226
             Q
Sbjct: 1346 PQ 1347



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 6/66 (9%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P L  +W R G  +    R T  ++     L+ +   PEDSG Y CR  N++G A   
Sbjct: 1264 GTPPLTFQWSRVGSSLPG--RATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAF 1317

Query: 1798 STLFVQ 1803
            + L VQ
Sbjct: 1318 AQLLVQ 1323



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 10/111 (9%)

Query: 3825 IVSTPPKFITQIKS--HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            ++   P  +  I++   TV     V FEC      DPK ++ W + G     GH    + 
Sbjct: 1422 VIQALPSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GHLRPGIV 1474

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
              G V + I +V   D+G+Y C A N  G   +   +  + LP I +  +V
Sbjct: 1475 QSGGV-VRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEV 1524



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 10/110 (9%)

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +EP   +  +  +  V ++  S+   V+EG+ + L C +   G    +V W   G S+  
Sbjct: 364  IEPAGSVPALGVTPTVRIE--SSSSQVAEGQTLDLNCLVA--GQAHAQVTWHKRGGSLP- 418

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             +R + +       L ++  T AD+GEY  R V   G+   S +V + +R
Sbjct: 419  -ARHQVHGS----RLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 463



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 53/231 (22%), Positives = 77/231 (33%), Gaps = 45/231 (19%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P   +     +VAE Q    +   +  G    +V W + G        L   H      L
Sbjct: 377  PTVRIESSSSQVAEGQT--LDLNCLVAGQAHAQVTWHKRG------GSLPARHQVHGSRL 428

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +  V P DSG Y CR +   G    S  + +Q +    L   H   +    ++E SS  
Sbjct: 429  RLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR----LSGSHSQGVAYPVRIESSS-- 482

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
                                     L+ G +    C +     P+  + WY  G  L S 
Sbjct: 483  -----------------------ASLANGHTLDLNCLVASQA-PH-TITWYKRGGSLPSR 517

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            H+   S       L I  V   DSGEY C   N  G   +S+ + +Q   S
Sbjct: 518  HQIVGSR------LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 562



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 20/129 (15%)

Query: 3978 QIQSQTSLV-EMETTKFECQLAPVGDPNMKVEWFFNGK--PLLHKNRFTPIYDFGYVAMN 4034
            +I+S +S V E +T    C +A  G  + +V W+  G   P  H+ R + +Y F      
Sbjct: 188  RIESSSSTVAEGQTLDLSCVVA--GQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ----- 240

Query: 4035 FGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASW 4094
                 P D+G+Y+CRA+N  GM E    +  TG  G    + L     S + IR   +S 
Sbjct: 241  ---ASPADAGQYVCRASN--GM-EASITVTVTGTQG----ANLAYPAGSTQPIRIEPSSS 290

Query: 4095 QVTPEQVVE 4103
            QV   Q ++
Sbjct: 291  QVAEGQTLD 299



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 9/92 (9%)

Query: 3823 EPIVSTPPKFIT---QIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            EP  S P   +T   +I+S + + +EG   +           ++ W++ G  LP+ H+  
Sbjct: 365  EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVH 424

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                     L +L V   DSGEY+CR V   G
Sbjct: 425  GS------RLRLLQVTPADSGEYVCRVVGSSG 450



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 10/97 (10%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            S S P+ ++  S+ P V EG+ + L C +     P   + W+  G S+   SR +T+   
Sbjct: 567  SVSPPIRIE--SSSPTVVEGQTLDLNCVVARQ--PQAIITWYKRGGSLP--SRHQTHGSH 620

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
                L +   + AD+GEY  RA N++ +   S ++ V
Sbjct: 621  ----LRLHQMSVADSGEYVCRANNNIDALEASIVISV 653



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            ++P+ +    +  +++GQ A F + LI    A + +EW   N+ L+     +   +    
Sbjct: 960  RSPVISIDPPSSTVQQGQDASF-KCLIHDGAAPISLEWKTRNQELEDNVHISPNGSI--- 1015

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             + I+   P + GTY C A NA G A +     VH   ++
Sbjct: 1016 -ITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTV 1054



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 11/124 (8%)

Query: 3826 VSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V +PP + T +  H +V+  E V+ +C       P L  +W R G  LP     R     
Sbjct: 1235 VESPP-YATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARNEL-- 1289

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
                L       EDSG Y CR  N  G     A +  +  P  +    +P G   +  +T
Sbjct: 1290 ----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 1345

Query: 3945 -QME 3947
             Q+E
Sbjct: 1346 PQLE 1349



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
           +V EG+ + LN    G+   ++TW + G  + P      HT    S L +P+   +D+  
Sbjct: 1   SVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPP------HTQVHGSRLRLPQVSPADSGE 54

Query: 561 YQCTAQNVAG 570
           Y C  +N +G
Sbjct: 55  YVCRVENGSG 64



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 42/178 (23%), Positives = 68/178 (38%), Gaps = 24/178 (13%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           VTEG+    +C V G  + +VTW+     +           +     L +  V+ +DSG 
Sbjct: 2   VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPH-------TQVHGSRLRLPQVSPADSGE 54

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQ----------VVAPKFVERFSTLNVREGEPVVLNA 512
             C   N SG       ++V+                 P  +E  S+ +V EG+ + LN 
Sbjct: 55  YVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEP-SSSHVAEGQTLDLNC 113

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G    ++TW K G  +      R  T G  S L + +   +D+  Y C     +G
Sbjct: 114 VVPGQAHAQVTWHKRGGSL----PARHQTHG--SLLRLHQVTPADSGEYVCHVVGTSG 165



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 9/85 (10%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            S+ P  I    SH V E E +   C V P +    ++ W++ G  LPS H+ R       
Sbjct: 665  SSMPIRIESSSSH-VAEGETLDLNC-VVPGQ-AHAQVTWHKRGGSLPSHHQTRGS----- 716

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
              L + +V   DSGEY+CR +   G
Sbjct: 717  -RLRLHHVSPADSGEYVCRVMGSSG 740



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 9/87 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            +  R   G  A F     G PTP +SW++           S+  + +  +  L++  + P
Sbjct: 1522 QEVRVPAGSAAVFPCIASGYPTPDISWSKLDG--------SLPPDSRLENNMLMLPSVRP 1573

Query: 139  GDEGEYTCTARNQYGEAICSVYIQ-PE 164
             D G Y CTA N+ G+     ++Q PE
Sbjct: 1574 QDAGTYVCTATNRQGKVKAFAHLQVPE 1600



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 9/95 (9%)

Query: 3822 EEPIVSTP-PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            E  ++  P P    +  S TV E + +   C V  +   +  + WY+ G  LP+ H+ R 
Sbjct: 176  EASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQ--VTWYKRGGSLPARHQVRG 233

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT 3915
                    L I      D+G+Y+CRA N      T
Sbjct: 234  ------SRLYIFQASPADAGQYVCRASNGMEASIT 262



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S   V EGQ +   C +     ++ +V W K G  +   H+   +H      L ++ +  
Sbjct: 384  SSSQVAEGQTLDLNCLV--AGQAHAQVTWHKRGGSLPARHQ---VHGS---RLRLLQVTP 435

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRLT 1535
             DSG Y CR V   GT E S  +T
Sbjct: 436  ADSGEYVCRVVGSSGTQEASVLVT 459



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 8/108 (7%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +PP  TT P    +    +   +C  +      +  +W   G  L    R    N+    
Sbjct: 1237 SPPYATTVPEHASVQAGETVQLQC--LAHGTPPLTFQWSRVGSSL--PGRATARNE---- 1288

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663
            +L        D+G Y C+ TN+ G A    +L V+G  G +    +P+
Sbjct: 1289 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPA 1336



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+   +R +T+     
Sbjct: 91   TRPIRIEPSSSH--VAEGQTLDLNCVVP--GQAHAQVTWHKRGGSLP--ARHQTHGSL-- 142

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +   T AD+GEY    V   G    S +V +
Sbjct: 143  --LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 175



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P +I    SH V E + +   C V P +    ++ WY+ G  LP+ H+           L
Sbjct: 866  PIYIEASSSH-VTEGQTLDLNC-VVPGQ-AHAQVTWYKRGGSLPARHQTHGS------QL 916

Query: 3890 DILYVYAEDSGEYICRAVNDFGED 3913
             +  V   DSGEY+CRA +  G +
Sbjct: 917  RLHLVSPADSGEYVCRAASGPGPE 940



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+ V  R +T+     
Sbjct: 280  TQPIRIEPSSSQ--VAEGQTLDLNCVVP--GQSHAQVTWHKRGGSLPV--RHQTHGSL-- 331

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +  A+ AD+GEY  R +        S +V +
Sbjct: 332  --LRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 364



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 8/96 (8%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P   +   S T +EG  +     +     P   I W K G S+ +  +        ++ L
Sbjct: 570 PPIRIESSSPTVVEGQTLDLNCVV--ARQPQAIITWYKRGGSLPSRHQTHG----SHLRL 623

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
             +S  + DSGEY CRA +     E   V+ V+P A
Sbjct: 624 HQMS--VADSGEYVCRANNNIDALEASIVISVSPSA 657



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 3695 PRFTVEIKDNID-VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P   + I+ ++  V  G  V F+C    +GDP  ++ W   G     G     +   G +
Sbjct: 1427 PSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVV 1480

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL--ESQLPQG 3802
               I ++   DAG+Y C ATN  G+  +   +   A   I +  E ++P G
Sbjct: 1481 R--IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAG 1529



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 10/123 (8%)

Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVAL 2169
            V +   TS++ +  G    FEC    + DP   + W   G  +R G         G V  
Sbjct: 1429 VLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVVR- 1481

Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL--DTQHPNGLEKIRQLEAQG 2227
             I +    D+G Y C ATN  G   +   L V     I +  + + P G   +    A G
Sbjct: 1482 -IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCIASG 1540

Query: 2228 HST 2230
            + T
Sbjct: 1541 YPT 1543



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 12/80 (15%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP--IHDFGYVALDIIDL 1509
            S++ V+ G  V FEC    + D   +V W K G     GH  RP  +   G V +  ++L
Sbjct: 1436 SVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GH-LRPGIVQSGGVVRIAHVEL 1487

Query: 1510 IAEDSGIYTCRAVNLVGTDE 1529
               D+G Y C A N  GT +
Sbjct: 1488 A--DAGQYRCTATNAAGTTQ 1505



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 9/100 (9%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++   P  +MP +++RV    AA F    I  G P   + W +    +   +RL      
Sbjct: 1511 LVQALPQISMP-QEVRVPAGSAAVFPC--IASGYPTPDISWSKLDGSLPPDSRLENN--- 1564

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                L +  V P+D+GTY C A N  G+    + L V  +
Sbjct: 1565 ---MLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPER 1601


>BX537391-1|CAD97633.1|  143|Homo sapiens hypothetical protein
           protein.
          Length = 143

 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 50/136 (36%), Positives = 75/136 (55%), Gaps = 2/136 (1%)

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
           +G H+L+I  VT  D+G+ TC+A N++G+ +F   L V  KE    P F+E+     V +
Sbjct: 1   NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVAD 60

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDG-GASTLDIPRAKASDAAWYQ 562
           G PV L  R +G P P+I W+K+   +  + + + +H D  G   L I  A   DA WY 
Sbjct: 61  GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 120

Query: 563 CTAQNVAGSTATRARL 578
            +A+N AG  +  ARL
Sbjct: 121 VSAKNEAGIVSCTARL 136



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 13/149 (8%)

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
            +G ++L+I     +D+G Y C+A N AG+     E VV+            K A+ PP  
Sbjct: 1    NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA-----------AKEAHKPPVF 49

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEY-TLRIS 4683
            IE L++  VA+G  +   C+++G P P + W K  + L   +    M +    Y  L I 
Sbjct: 50   IEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQ 109

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             A  ED G Y   A N AG V+  A+L V
Sbjct: 110  GATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 44/134 (32%), Positives = 58/134 (43%), Gaps = 7/134 (5%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LII  V   D+ ++  +A NR G    S  LVV  K         PP F    QN  V  
Sbjct: 6    LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-----PPVFIEKLQNTGVAD 60

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYE 4585
            G  VRL+ +V G  P  ++W K  + +        + +D  G   LLI  A  +D+G Y 
Sbjct: 61   GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 120

Query: 4586 CVAINSAGEARCDA 4599
              A N AG   C A
Sbjct: 121  VSAKNEAGIVSCTA 134



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 45/141 (31%), Positives = 66/141 (46%), Gaps = 5/141 (3%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G+  L I    + D+G Y+C ATN+ GQ   S++L    K   + P F   +QN  G+ D
Sbjct: 2    GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN-TGVAD 60

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST-RIKTVSD-FGFVVLDIAYTQNHDSGE 3221
            G     EC V+ V  P  +I W    + + HST R+    D  G++ L I      D+G 
Sbjct: 61   GYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGW 118

Query: 3222 YVCRAYNKYGEDFTRATINCY 3242
            Y   A N+ G     A ++ Y
Sbjct: 119  YTVSAKNEAGIVSCTARLDVY 139



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 2/135 (1%)

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
            ++L I      D G Y C+A N AG+ + + +L V   +       +  L++  V +G P
Sbjct: 4    HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYP 63

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRA 4795
             + + ++     P I W +E   +  + D   +H+ N+    LLI    +ED G +T  A
Sbjct: 64   VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 123

Query: 4796 TTAAGQVETSAKLVV 4810
               AG V  +A+L V
Sbjct: 124  KNEAGIVSCTARLDV 138



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            KPP+F +K+Q   V +    R E    G P P I W +EN  + +S D   +H  +   I
Sbjct: 45   KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 104

Query: 4468 -LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             L+I+    ED+  +   A+N  G   C+A L V
Sbjct: 105  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 24/88 (27%), Positives = 41/88 (46%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+F +  +N   A G   + E ++ G P P + W ++   L         + +  G + 
Sbjct: 46  PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 105

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS 158
           LLI+     D G YT +A+N+ G   C+
Sbjct: 106 LLIQGATKEDAGWYTVSAKNEAGIVSCT 133



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 1/92 (1%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES-GNHAL 450
           P F++  Q+  V +G   R +CRV G P P++ W   +  +    +   +  ++ G   L
Sbjct: 47  PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 106

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           +I   T  D+G  T  A+N++G  +   RL+V
Sbjct: 107 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 32/91 (35%), Positives = 47/91 (51%), Gaps = 5/91 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS-RFKTYYD-FGF 1234
            PVF++ L N   V++G  + LECR+  +G P  ++ W     S+T  + R   + D  G+
Sbjct: 47   PVFIEKLQNTG-VADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGY 103

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
            + L I  AT  D G YTV A N  G    +A
Sbjct: 104  ICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 134



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 5/101 (4%)

Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
           ++  + P FI  LQ+ G + +G     E ++  V  P  ++ W K+   +T S+   S+ 
Sbjct: 41  KEAHKPPVFIEKLQNTG-VADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMH 97

Query: 824 --NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             N GY+ L I     EDAG YTV A N+ G    TA + V
Sbjct: 98  QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
           PP   +K +N+ + +G   + + ++ G P P++ W K  + L +S     +   NH    
Sbjct: 46  PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 105

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           L ++   K D+G YT+ A+N  G +  +  L V
Sbjct: 106 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA-TGS 3742
            E+ +  ++ + P   +E   N  V +G PV  +CRV  +G P  +I W         +  
Sbjct: 35   ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTD 92

Query: 3743 RVHTLND-FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            RV    D  G+I L I      DAG YT  A N+ G  + TA++
Sbjct: 93   RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 136



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR-NEKLIEDSSRITKTHD-FGY 2433
            PVF + LQN   + +G     +CR++ V  P  ++ W + NE L   + R++   D  GY
Sbjct: 47   PVFIEKLQNT-GVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 103

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
            + + I     ED G Y   A N  G
Sbjct: 104  ICLLIQGATKEDAGWYTVSAKNEAG 128



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 4/97 (4%)

Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--F 691
           + PP FI  L++    +G  +  E R+  +G P  +I W K  +S+  S+   S+ +   
Sbjct: 44  HKPPVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNH 101

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           GYI L +     +D+G YT  A +  G+    A L V
Sbjct: 102 GYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH--DFGYV 1768
            PVF   +++  VA+      E R++ V  P+  + W +    +  S    +MH  + GY+
Sbjct: 47   PVFIEKLQNTGVADGYPVRLECRVLGVPPPQ--IFWKKENESLTHSTDRVSMHQDNHGYI 104

Query: 1769 ALNMKYVNPEDSGTYTCRAINELG 1792
             L ++    ED+G YT  A NE G
Sbjct: 105  CLLIQGATKEDAGWYTVSAKNEAG 128



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGY 2299
            PP F+ +L+ T  V +G     EC+V  V  P +  +   N     S  R  +  D  GY
Sbjct: 46   PPVFIEKLQNTG-VADGYPVRLECRVLGVPPPQIFWK-KENESLTHSTDRVSMHQDNHGY 103

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALG--HCTSAISMTVT 2335
            + L IQ    EDAG Y+V A N  G   CT+ + + ++
Sbjct: 104  ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 141



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 5/95 (5%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHD-FGY 1100
            P F+  L+ T  + +G     E RV         + W    + +T S +R+  + D  GY
Sbjct: 47   PVFIEKLQNTG-VADGYPVRLECRVLGVPP--PQIFWKKENESLTHSTDRVSMHQDNHGY 103

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            + L I     ED+G YTV A+N AG    +A + V
Sbjct: 104  ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVS 2832
            VFI  L N    +G  +  EC V     P  +I W   N+ L   T   S H  +  Y+ 
Sbjct: 48   VFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYIC 105

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I    +ED+G YT  A N  G  + +  L
Sbjct: 106  LLIQGATKEDAGWYTVSAKNEAGIVSCTARL 136



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 4/70 (5%)

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
            G  +L I+ VT  DAG YTC A N  GQ + S  L +  K+      + P  +EK+Q   
Sbjct: 2    GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE----AHKPPVFIEKLQNTG 57

Query: 1025 DASRYSKRTE 1034
             A  Y  R E
Sbjct: 58   VADGYPVRLE 67



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 4/110 (3%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S +++ +    E+  PP F     +  +++      ECR++ V     ++ W    + L 
Sbjct: 31   SFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLT 88

Query: 3602 TGS-RVKTIND-FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              + RV    D  G++ L I G  + DAG YT  A N  G  + + +L V
Sbjct: 89   HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 18/57 (31%), Positives = 27/57 (47%)

Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            E VV   +A  PPVF+       V +G   R  CRV G P P++ W     ++ + +
Sbjct: 35   ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 91



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/37 (48%), Positives = 24/37 (64%)

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            L I  V  RDAG+YTC ATNR G+ + S +L V  ++
Sbjct: 6    LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 42



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYD-FGYV 2035
            P F + ++N  V +G+PV LE  +  V  P  ++ W      +     R     D  GY+
Sbjct: 47   PVFIEKLQNTGVADGYPVRLECRVLGV--PPPQIFWKKENESLTHSTDRVSMHQDNHGYI 104

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             L I  A  ED G Y   A N  G    T+ + V
Sbjct: 105  CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF- 962
            E+ + P F   +++   + +G     E R+  +G    ++ W K+   +  S+   +   
Sbjct: 42   EAHKPPVFIEKLQNT-GVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQ 98

Query: 963  -NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             N GY+ L I+  T  DAG YT  A N  G  + +A L +
Sbjct: 99   DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 5/98 (5%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTSND- 1898
            ++ P FI +L   T +++G     ECR+   P P  ++ W   N  +  S  R     D 
Sbjct: 44   HKPPVFIEKLQN-TGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDN 100

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             G+  L I     ED+G YT  A N  G    + RL+V
Sbjct: 101  HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 138



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTVYD-MGF 3886
            PP FI ++++  V +   VR ECRV     P  +I W + N  L  S  R     D  G+
Sbjct: 46   PPVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGY 103

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
            + L I     ED+G Y   A N+ G
Sbjct: 104  ICLLIQGATKEDAGWYTVSAKNEAG 128



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 8/95 (8%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD---Y 1367
            P F   L N    +G  V LECR+  +G    ++ W    + + T    R +   D   Y
Sbjct: 47   PVFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESL-THSTDRVSMHQDNHGY 103

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            + L +     ED+G YT  A N+ G  + SC  R+
Sbjct: 104  ICLLIQGATKEDAGWYTVSAKNEAG--IVSCTARL 136



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLK-SGSRFT-ETNNFGFV 1635
            P+    L+N  + +G     E R++ V     ++ W   N+ L  S  R +   +N G++
Sbjct: 47   PVFIEKLQNTGVADGYPVRLECRVLGVPPP--QIFWKKENESLTHSTDRVSMHQDNHGYI 104

Query: 1636 ALDIMSCLPEDSGTYTCRAINALG 1659
             L I     ED+G YT  A N  G
Sbjct: 105  CLLIQGATKEDAGWYTVSAKNEAG 128


>BC067107-1|AAH67107.1|  814|Homo sapiens putative neuronal cell
            adhesion molecule protein.
          Length = 814

 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 82/288 (28%), Positives = 125/288 (43%), Gaps = 29/288 (10%)

Query: 4428 ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAEN 4487
            ARF+ +  G P PLI W +   PI    D + +T   K +L I  +  ED  +F  VA N
Sbjct: 156  ARFQCQIHGLPKPLITWEKNRVPI--DTDNERYTLLPKGVLQITGLRAEDGGIFHCVASN 213

Query: 4488 RGG-TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
                     A L V      G G    P+  +  +N+ +T  Q   L+   TG     V 
Sbjct: 214  IASIRISHGARLTVS---GSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVS 270

Query: 4547 WLK-NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
            W + +G+ +  +     ++  GT  L+I +   Q SG Y C A               + 
Sbjct: 271  WSRLDGRPIGVE----GIQVLGTGNLIISDVTVQHSGVYVCAA---------------NR 311

Query: 4606 PATKDKPKPQTK-AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
            P T+ +   Q +    AP E ++  +      G    F+C+  G+P P V W K  +++ 
Sbjct: 312  PGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLG 371

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            P  + ++    +  TL IS   PEDE  Y+CVA NSAG    +A+L V
Sbjct: 372  PGGHVRLKN--NNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 89/309 (28%), Positives = 135/309 (43%), Gaps = 40/309 (12%)

Query: 272 PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
           P+ +  +EG  A+FQ Q+ G P+P +TW K        N+  I T               
Sbjct: 145 PQATVGEEGGVARFQCQIHGLPKPLITWEK--------NRVPIDT--------------- 181

Query: 332 DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
           D+  YTLL   P G +  +G  A +      V    +        R T      S     
Sbjct: 182 DNERYTLL---PKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSG-SGAYKE 237

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P  +   ++  +T  +    +C  TG P P V+W  ++ R I  +    I V  +GN  L
Sbjct: 238 PAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVE---GIQVLGTGN--L 292

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP-KFVERFSTLNVREGEPVV 509
           +I++VT+  SGV  C A N+ G    + R     +  V AP +FV+   +++   G   +
Sbjct: 293 IISDVTVQHSGVYVCAA-NRPGT---RVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAM 348

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
              +A G P P +TW K+G  + P   +R+  +   STL I      D A YQC A+N A
Sbjct: 349 FTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNN--STLTISGIGPEDEAIYQCVAENSA 406

Query: 570 GSTATRARL 578
           GS+   ARL
Sbjct: 407 GSSQASARL 415



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 85/316 (26%), Positives = 134/316 (42%), Gaps = 30/316 (9%)

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
            +G G     +F +   +     GQ + LD +V GT P+ + W KNG ++ P+  +  L  
Sbjct: 34   EGLGHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVEL-PESTHSTLLA 92

Query: 4566 DGTYTL--LILE--AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +G+  +    LE    P D G YECVA N  G        VVS        K + +AA  
Sbjct: 93   NGSLMIRHFRLEPGGSPSDEGDYECVAQNRFG-------LVVS-------RKARIQAATM 138

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
                + P +  +  EG    F C+I G P P + W K    I      +      +  L+
Sbjct: 139  SDFHVHP-QATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDN--ERYTLLPKGVLQ 195

Query: 4682 ISEAFPEDEGDYKCVAYNSAG-RVTVAAKLKVT-QPDQADNLPA-LTPLRDIVVYEGQPA 4738
            I+    ED G + CVA N A  R++  A+L V+     A   PA L    ++ +   Q A
Sbjct: 196  ITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTA 255

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              +   T   +P + W R           Q++  GN   L+I +   + +G + C A   
Sbjct: 256  VLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGN---LIISDVTVQHSGVYVCAANRP 312

Query: 4799 AGQVETSA--KLVVKS 4812
              +V  +A  +LVV++
Sbjct: 313  GTRVRRTAQGRLVVQA 328



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 96/385 (24%), Positives = 142/385 (36%), Gaps = 42/385 (10%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE------DSAVFAAVAENR 4488
            +G P   I W +    +   P+    T      L+IR   +E      D   +  VA+NR
Sbjct: 66   EGTPPVRITWRKNGVEL---PESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNR 122

Query: 4489 GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYW 4547
             G       LVV  K R     +    F +  Q      G + R   ++ G  KP+ + W
Sbjct: 123  FG-------LVVSRKARIQAATM--SDFHVHPQATVGEEGGVARFQCQIHGLPKPL-ITW 172

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             KN   +  D     L   G   +  L A  +D G + CVA N A          +S  A
Sbjct: 173  EKNRVPIDTDNERYTLLPKGVLQITGLRA--EDGGIFHCVASNIASIR-------ISHGA 223

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                    + A   P  ++ P    +     A+   C   G P P V W + D      +
Sbjct: 224  RLTVSGSGSGAYKEPAILVGPENLTLTVHQTAV-LECVATGNPRPIVSWSRLDGRPIGVE 282

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV--TVAAKLKVTQPDQADNLPALT 4725
              Q+  T +   L IS+   +  G Y C A     RV  T   +L V  P +    P   
Sbjct: 283  GIQVLGTGN---LIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHP--- 336

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
              + I    G  A F  Q   +  P + WL+ G ++   P   +  + NN+ L I     
Sbjct: 337  --QSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLG--PGGHVRLKNNNSTLTISGIGP 392

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
            ED   + C A  +AG  + SA+L V
Sbjct: 393  EDEAIYQCVAENSAGSSQASARLTV 417



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 56/183 (30%), Positives = 79/183 (43%), Gaps = 21/183 (11%)

Query: 4425 HEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            H+ A  E    G P P++ W R +  PI       I    T + LII  V V+ S V+  
Sbjct: 252  HQTAVLECVATGNPRPIVSWSRLDGRPIGVE---GIQVLGTGN-LIISDVTVQHSGVYVC 307

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIV---PPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
             A NR GT            RR  +G +V   P  F    Q+++  +G       +  G 
Sbjct: 308  AA-NRPGT----------RVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGE 356

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P  V WLKNG+ + P     +  ++   TL I    P+D   Y+CVA NSAG ++  A 
Sbjct: 357  PPPHVTWLKNGQVLGPG--GHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASAR 414

Query: 4601 CVV 4603
              V
Sbjct: 415  LTV 417



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 47/167 (28%), Positives = 74/167 (44%), Gaps = 10/167 (5%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES--GNHALMITNVTLSDSGVV 463
           G+    DCRV G P   +TW  N  ++ +  +  +L N S    H  +    + SD G  
Sbjct: 56  GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDY 115

Query: 464 TCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            CVA+N+ G   + + R+    +   ++   V   +T+   EG       +  G P P I
Sbjct: 116 ECVAQNRFGLVVSRKARI----QAATMSDFHVHPQATVG-EEGGVARFQCQIHGLPKPLI 170

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           TW+K+ VPI  + E   +T      L I   +A D   + C A N+A
Sbjct: 171 TWEKNRVPIDTDNER--YTLLPKGVLQITGLRAEDGGIFHCVASNIA 215



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 2/92 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +P +  Q P++     G  A F  Q  G P P VTW KNGQ ++    H +   +N++TL
Sbjct: 328 APAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ-VLGPGGH-VRLKNNNSTL 385

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            +      D   Y  +AEN  G    S  L V
Sbjct: 386 TISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 3/99 (3%)

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           +FV+  Q      G    F C+  G P P VTW  N  Q+     H  L N   N  L I
Sbjct: 331 EFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNG-QVLGPGGHVRLKN--NNSTLTI 387

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
           + +   D  +  CVA N +G +    RL V+  E +  P
Sbjct: 388 SGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGP 426



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 3/74 (4%)

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI---PRAKASDAAWY 561
           G+P+VL+ R  GTP  RITW+K+GV +  +    +  +G          P    SD   Y
Sbjct: 56  GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDY 115

Query: 562 QCTAQNVAGSTATR 575
           +C AQN  G   +R
Sbjct: 116 ECVAQNRFGLVVSR 129



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 49/217 (22%), Positives = 80/217 (36%), Gaps = 9/217 (4%)

Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ 4458
            R  +G +    P  F +  Q         A F  +  GEP P + W +    +   P   
Sbjct: 318  RTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVL--GPGGH 375

Query: 4459 IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL 4518
            +   +  S L I  +  ED A++  VAEN  G+++ SA L V         G+  P   +
Sbjct: 376  VRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTV-----LWAEGLPGPPRNV 430

Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEAY 4577
             A +V+ T  + V     +  TK I  Y L   K    P++  +      T+  L+ +  
Sbjct: 431  RAVSVSSTEVR-VSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAVSKSTFQHLVSDLE 489

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P  +  +   A    G +      + S       P P
Sbjct: 490  PSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPP 526



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 1296 RRTKQVREDITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            RRT Q R    V+QAP +F +   +I    GT     C+ Q  G+    V W  NG+ + 
Sbjct: 317  RRTAQGR---LVVQAPAEFVQHPQSISRPAGTTAMFTCQAQ--GEPPPHVTWLKNGQVLG 371

Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             G   R   + +   L +  + PED  +Y C A N  G +  S  L V+
Sbjct: 372  PGGHVR--LKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVL 418



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 7/113 (6%)

Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG--RPFATGSRVHTLNDFGFIA 3754
            F VE  D++ VP G P+  DCRVE  G P +RI W  NG   P +T S +          
Sbjct: 44   FAVEPSDDVAVP-GQPIVLDCRVE--GTPPVRITWRKNGVELPESTHSTLLANGSLMIRH 100

Query: 3755 LDIDYIYA-RDAGEYTCRATNKWGSATT-TAKITCSAKRDIVLESQLPQGMSG 3805
              ++   +  D G+Y C A N++G   +  A+I  +   D  +  Q   G  G
Sbjct: 101  FRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEG 153



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 4/103 (3%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V QAP    Q         G +A + C+ +  P P+  V W  NG+VL  G   R  N+ 
Sbjct: 325  VVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPH--VTWLKNGQVLGPGGHVRLKNNN 382

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              + L I  +  ED   Y C A N+ G + +S RL V   E +
Sbjct: 383  --STLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGL 423



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   V+   +I  P G    F C+ +  G+P   + W  NG+    G  V   N+     
Sbjct: 329  PAEFVQHPQSISRPAGTTAMFTCQAQ--GEPPPHVTWLKNGQVLGPGGHVRLKNNNS--T 384

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            L I  I   D   Y C A N  GS+  +A++T
Sbjct: 385  LTISGIGPEDEAIYQCVAENSAGSSQASARLT 416



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 18/52 (34%), Positives = 25/52 (48%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            + P  FV  P +++   G  A F C+  G P P V WL NG  +  G   +L
Sbjct: 327  QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRL 378



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 5/105 (4%)

Query: 1699 RHSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN 1757
            R +AQ  ++ QAP  F    + I       A F  +    G+P   V WL+NG  +    
Sbjct: 317  RRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQA--QGEPPPHVTWLKNGQVLGPGG 374

Query: 1758 RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             +   ++     L +  + PED   Y C A N  G +  S+ L V
Sbjct: 375  HVRLKNNNS--TLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 261 GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
           G    P I   P N  L     A  +   +GNPRP V+W +   R I     +++ T N 
Sbjct: 233 GAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGN- 291

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCI--VTSGYLAVESPTESYVQDQRS 368
             L + +     SG Y   A  P   +     G L V++P E +VQ  +S
Sbjct: 292 --LIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAE-FVQHPQS 338



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 33/104 (31%), Positives = 43/104 (41%), Gaps = 5/104 (4%)

Query: 56  GDRQPITA-GRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE 114
           G R   TA GR    +P  F Q  ++     G  A F  + +G P P V+W +    L  
Sbjct: 313 GTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGP 372

Query: 115 CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
                ++ N  T    L I  IGP DE  Y C A N  G +  S
Sbjct: 373 GGHVRLKNNNST----LTISGIGPEDEAIYQCVAENSAGSSQAS 412



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 5/81 (6%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            F Q  Q+I     G TA F C+    G+P   V W +N +++     +   ++    ++T
Sbjct: 332  FVQHPQSISR-PAGTTAMFTCQA--QGEPPPHVTWLKNGQVLGPGGHVRLKNNNS--TLT 386

Query: 2438 ISHVRDEDEGVYMCRASNLLG 2458
            IS +  EDE +Y C A N  G
Sbjct: 387  ISGIGPEDEAIYQCVAENSAG 407



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/90 (33%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 1446 FVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALD 1505
            FV  P+SI     G    F C+ +     +  V W KNGQ +  G   R  ++     L 
Sbjct: 332  FVQHPQSISRPA-GTTAMFTCQAQGEPPPH--VTWLKNGQVLGPGGHVRLKNNNS--TLT 386

Query: 1506 IIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            I  +  ED  IY C A N  G+ + S RLT
Sbjct: 387  ISGIGPEDEAIYQCVAENSAGSSQASARLT 416



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 4/88 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+ H  +I    G    F C  +   +P   + W  N + L  G   +  ++ S  +L I
Sbjct: 332  FVQHPQSISRPAGTTAMFTCQAQG--EPPPHVTWLKNGQVLGPGGHVRLKNNNS--TLTI 387

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            +    ED  IY C A NS GS+  S  L
Sbjct: 388  SGIGPEDEAIYQCVAENSAGSSQASARL 415



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILY---CYEENSGEYECVATNKLGR-DS 3367
            P +++ W  NG +LP         +  ++I            + G+YECVA N+ G   S
Sbjct: 69   PPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVS 128

Query: 3368 TKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398
             KA ++  +  +  +  Q   G EGG+ + Q
Sbjct: 129  RKARIQAATMSDFHVHPQATVGEEGGVARFQ 159



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 2638 VQQAPI-FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            V QAP  F  H +S  +   G       Q +    P+  + W KNG  L  G  ++   +
Sbjct: 325  VVQAPAEFVQHPQSISRPA-GTTAMFTCQAQGEPPPH--VTWLKNGQVLGPGGHVRLKNN 381

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                TL+I+ +  +D  IY C A N  G + ++A + +
Sbjct: 382  NS--TLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            V W  NG+ +     ++  ++     L I+ +  ED  +Y  VA N+AG +Q SA +TV
Sbjct: 361  VTWLKNGQVLGPGGHVRLKNNNS--TLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 1/49 (2%)

Query: 4117 PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI-VNGSRYKLTYDGM 4164
            P A   EEG  ARF C++ G PKP + W  N   I  +  RY L   G+
Sbjct: 145  PQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGV 193



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 43/158 (27%), Positives = 65/158 (41%), Gaps = 16/158 (10%)

Query: 3076 GDQSMVIEWFYNGKTI-EASHRIRTVYAFGMVVLEIL----GTKTTDSGTYSCRATNKWG 3130
            G   + I W  NG  + E++H   T+ A G +++       G   +D G Y C A N++G
Sbjct: 67   GTPPVRITWRKNGVELPESTHS--TLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFG 124

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
               +S K      +      F  H Q   G ++G  A F+C +  +  P   I W  N  
Sbjct: 125  LV-VSRKARIQAATMSD---FHVHPQATVG-EEGGVARFQCQIHGLPKP--LITWEKNRV 177

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            P+       T+   G  VL I   +  D G + C A N
Sbjct: 178  PIDTDNERYTLLPKG--VLQITGLRAEDGGIFHCVASN 213



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/114 (25%), Positives = 41/114 (35%), Gaps = 10/114 (8%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A F C+ +    PH+T  W  NGQ +  G   R  ++     L I     ED   Y 
Sbjct: 344  GTTAMFTCQAQGEPPPHVT--WLKNGQVLGPGGHVRLKNNNS--TLTISGIGPEDEAIYQ 399

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEP 2237
            C A N  G +  +  L V     +      P     +R +       R+   EP
Sbjct: 400  CVAENSAGSSQASARLTVLWAEGL------PGPPRNVRAVSVSSTEVRVSWSEP 447



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
           LG  +    A +P +     G       ++ G P  R+TW KNG  L  S    ++   +
Sbjct: 36  LGHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGS 95

Query: 320 HTTLRVR---NTQKSDSGHYTLLAENPNGCIVT 349
                 R       SD G Y  +A+N  G +V+
Sbjct: 96  LMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVS 128



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 15/169 (8%)

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121
            EG +A ++  +   G    +I W  N   I+  +   T+   G  VL+I G +  D G +
Sbjct: 152  EGGVARFQCQI--HGLPKPLITWEKNRVPIDTDNERYTLLPKG--VLQITGLRAEDGGIF 207

Query: 3122 SCRATNKWG-QAEISVKLECVDKSKG--QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
             C A+N    +     +L       G  ++P      +N+  L   Q+A  EC  V   +
Sbjct: 208  HCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLT-LTVHQTAVLEC--VATGN 264

Query: 3179 PDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            P   + W   +G+P+     I+ +     ++ D+  T  H SG YVC A
Sbjct: 265  PRPIVSWSRLDGRPI-GVEGIQVLGTGNLIISDV--TVQH-SGVYVCAA 309



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYV---NPEDSGTYTCRAINELGEA 1794
            G P +R+ W +NGV +  S   T + +   +  + +     +P D G Y C A N  G  
Sbjct: 67   GTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLV 126

Query: 1795 VT 1796
            V+
Sbjct: 127  VS 128



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            IS   G  A F  + +  G+    V WLK+G+ +     +    N     LTI  +   D
Sbjct: 339  ISRPAGTTAMFTCQAQ--GEPPPHVTWLKNGQVLGPGGHVRLKNNNS--TLTISGIGPED 394

Query: 979  AGHYTCRAYNAIGQATTSANLTIV 1002
               Y C A N+ G +  SA LT++
Sbjct: 395  EAIYQCVAENSAGSSQASARLTVL 418



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 4/66 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           +GG A+F+ ++ G P P+++W + + P+   N+   RY      V L I  +   D G +
Sbjct: 152 EGGVARFQCQIHGLPKPLITWEKNRVPIDTDNE---RYTLLPKGV-LQITGLRAEDGGIF 207

Query: 145 TCTARN 150
            C A N
Sbjct: 208 HCVASN 213


>BC042054-1|AAH42054.1|  814|Homo sapiens putative neuronal cell
            adhesion molecule protein.
          Length = 814

 Score = 95.5 bits (227), Expect = 4e-18
 Identities = 82/288 (28%), Positives = 125/288 (43%), Gaps = 29/288 (10%)

Query: 4428 ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAEN 4487
            ARF+ +  G P PLI W +   PI    D + +T   K +L I  +  ED  +F  VA N
Sbjct: 156  ARFQCQIHGLPKPLITWEKNRVPI--DTDNERYTLLPKGVLQITGLRAEDGGIFHCVASN 213

Query: 4488 RGG-TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
                     A L V      G G    P+  +  +N+ +T  Q   L+   TG     V 
Sbjct: 214  IASIRISHGARLTVS---GSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVS 270

Query: 4547 WLK-NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
            W + +G+ +  +     ++  GT  L+I +   Q SG Y C A               + 
Sbjct: 271  WSRLDGRPIGVE----GIQVLGTGNLIISDVTVQHSGVYVCAA---------------NR 311

Query: 4606 PATKDKPKPQTK-AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
            P T+ +   Q +    AP E ++  +      G    F+C+  G+P P V W K  +++ 
Sbjct: 312  PGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLG 371

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            P  + ++    +  TL IS   PEDE  Y+CVA NSAG    +A+L V
Sbjct: 372  PGGHVRLKN--NNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 89/309 (28%), Positives = 135/309 (43%), Gaps = 40/309 (12%)

Query: 272 PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
           P+ +  +EG  A+FQ Q+ G P+P +TW K        N+  I T               
Sbjct: 145 PQATVGEEGGVARFQCQIHGLPKPLITWEK--------NRVPIDT--------------- 181

Query: 332 DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
           D+  YTLL   P G +  +G  A +      V    +        R T      S     
Sbjct: 182 DNERYTLL---PKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSG-SGAYKE 237

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHAL 450
           P  +   ++  +T  +    +C  TG P P V+W  ++ R I  +    I V  +GN  L
Sbjct: 238 PAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVE---GIQVLGTGN--L 292

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP-KFVERFSTLNVREGEPVV 509
           +I++VT+  SGV  C A N+ G    + R     +  V AP +FV+   +++   G   +
Sbjct: 293 IISDVTVQHSGVYVCAA-NRPGT---RVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAM 348

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
              +A G P P +TW K+G  + P   +R+  +   STL I      D A YQC A+N A
Sbjct: 349 FTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNN--STLTISGIGPEDEAIYQCVAENSA 406

Query: 570 GSTATRARL 578
           GS+   ARL
Sbjct: 407 GSSQASARL 415



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 85/316 (26%), Positives = 134/316 (42%), Gaps = 30/316 (9%)

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
            +G G     +F +   +     GQ + LD +V GT P+ + W KNG ++ P+  +  L  
Sbjct: 34   EGLGHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVEL-PESTHSTLLA 92

Query: 4566 DGTYTL--LILE--AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +G+  +    LE    P D G YECVA N  G        VVS        K + +AA  
Sbjct: 93   NGSLMIRHFRLEPGGSPSDEGDYECVAQNRFG-------LVVS-------RKARIQAATM 138

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
                + P +  +  EG    F C+I G P P + W K    I      +      +  L+
Sbjct: 139  SDFHVHP-QATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDN--ERYTLLPKGVLQ 195

Query: 4682 ISEAFPEDEGDYKCVAYNSAG-RVTVAAKLKVT-QPDQADNLPA-LTPLRDIVVYEGQPA 4738
            I+    ED G + CVA N A  R++  A+L V+     A   PA L    ++ +   Q A
Sbjct: 196  ITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTA 255

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              +   T   +P + W R           Q++  GN   L+I +   + +G + C A   
Sbjct: 256  VLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGN---LIISDVTVQHSGVYVCAANRP 312

Query: 4799 AGQVETSA--KLVVKS 4812
              +V  +A  +LVV++
Sbjct: 313  GTRVRRTAQGRLVVQA 328



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 96/385 (24%), Positives = 142/385 (36%), Gaps = 42/385 (10%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE------DSAVFAAVAENR 4488
            +G P   I W +    +   P+    T      L+IR   +E      D   +  VA+NR
Sbjct: 66   EGTPPVRITWRKNGVEL---PESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNR 122

Query: 4489 GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYW 4547
             G       LVV  K R     +    F +  Q      G + R   ++ G  KP+ + W
Sbjct: 123  FG-------LVVSRKARIQAATM--SDFHVHPQATVGEEGGVARFQCQIHGLPKPL-ITW 172

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             KN   +  D     L   G   +  L A  +D G + CVA N A          +S  A
Sbjct: 173  EKNRVPIDTDNERYTLLPKGVLQITGLRA--EDGGIFHCVASNIASIR-------ISHGA 223

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK 4667
                    + A   P  ++ P    +     A+   C   G P P V W + D      +
Sbjct: 224  RLTVSGSGSGAYKEPAILVGPENLTLTVHQTAV-LECVATGNPRPIVSWSRLDGRPIGVE 282

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV--TVAAKLKVTQPDQADNLPALT 4725
              Q+  T +   L IS+   +  G Y C A     RV  T   +L V  P +    P   
Sbjct: 283  GIQVLGTGN---LIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHP--- 336

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
              + I    G  A F  Q   +  P + WL+ G ++   P   +  + NN+ L I     
Sbjct: 337  --QSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLG--PGGHVRLKNNNSTLTISGIGP 392

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
            ED   + C A  +AG  + SA+L V
Sbjct: 393  EDEAIYQCVAENSAGSSQASARLTV 417



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 56/183 (30%), Positives = 79/183 (43%), Gaps = 21/183 (11%)

Query: 4425 HEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            H+ A  E    G P P++ W R +  PI       I    T + LII  V V+ S V+  
Sbjct: 252  HQTAVLECVATGNPRPIVSWSRLDGRPIGVE---GIQVLGTGN-LIISDVTVQHSGVYVC 307

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIV---PPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
             A NR GT            RR  +G +V   P  F    Q+++  +G       +  G 
Sbjct: 308  AA-NRPGT----------RVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGE 356

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P  V WLKNG+ + P     +  ++   TL I    P+D   Y+CVA NSAG ++  A 
Sbjct: 357  PPPHVTWLKNGQVLGPG--GHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASAR 414

Query: 4601 CVV 4603
              V
Sbjct: 415  LTV 417



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 47/167 (28%), Positives = 74/167 (44%), Gaps = 10/167 (5%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES--GNHALMITNVTLSDSGVV 463
           G+    DCRV G P   +TW  N  ++ +  +  +L N S    H  +    + SD G  
Sbjct: 56  GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDY 115

Query: 464 TCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            CVA+N+ G   + + R+    +   ++   V   +T+   EG       +  G P P I
Sbjct: 116 ECVAQNRFGLVVSRKARI----QAATMSDFHVHPQATVG-EEGGVARFQCQIHGLPKPLI 170

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           TW+K+ VPI  + E   +T      L I   +A D   + C A N+A
Sbjct: 171 TWEKNRVPIDTDNER--YTLLPKGVLQITGLRAEDGGIFHCVASNIA 215



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 2/92 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           +P +  Q P++     G  A F  Q  G P P VTW KNGQ ++    H +   +N++TL
Sbjct: 328 APAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ-VLGPGGH-VRLKNNNSTL 385

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            +      D   Y  +AEN  G    S  L V
Sbjct: 386 TISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 3/99 (3%)

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           +FV+  Q      G    F C+  G P P VTW  N  Q+     H  L N   N  L I
Sbjct: 331 EFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNG-QVLGPGGHVRLKN--NNSTLTI 387

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
           + +   D  +  CVA N +G +    RL V+  E +  P
Sbjct: 388 SGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGP 426



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 3/74 (4%)

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI---PRAKASDAAWY 561
           G+P+VL+ R  GTP  RITW+K+GV +  +    +  +G          P    SD   Y
Sbjct: 56  GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDY 115

Query: 562 QCTAQNVAGSTATR 575
           +C AQN  G   +R
Sbjct: 116 ECVAQNRFGLVVSR 129



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 49/217 (22%), Positives = 80/217 (36%), Gaps = 9/217 (4%)

Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ 4458
            R  +G +    P  F +  Q         A F  +  GEP P + W +    +   P   
Sbjct: 318  RTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVL--GPGGH 375

Query: 4459 IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL 4518
            +   +  S L I  +  ED A++  VAEN  G+++ SA L V         G+  P   +
Sbjct: 376  VRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTV-----LWAEGLPGPPRNV 430

Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEAY 4577
             A +V+ T  + V     +  TK I  Y L   K    P++  +      T+  L+ +  
Sbjct: 431  RAVSVSSTEVR-VSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAVSKSTFQHLVSDLE 489

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
            P  +  +   A    G +      + S       P P
Sbjct: 490  PSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPP 526



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 1296 RRTKQVREDITVMQAP-QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            RRT Q R    V+QAP +F +   +I    GT     C+ Q  G+    V W  NG+ + 
Sbjct: 317  RRTAQGR---LVVQAPAEFVQHPQSISRPAGTTAMFTCQAQ--GEPPPHVTWLKNGQVLG 371

Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             G   R   + +   L +  + PED  +Y C A N  G +  S  L V+
Sbjct: 372  PGGHVR--LKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVL 418



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 7/113 (6%)

Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG--RPFATGSRVHTLNDFGFIA 3754
            F VE  D++ VP G P+  DCRVE  G P +RI W  NG   P +T S +          
Sbjct: 44   FAVEPSDDVAVP-GQPIVLDCRVE--GTPPVRITWRKNGVELPESTHSTLLANGSLMIRH 100

Query: 3755 LDIDYIYA-RDAGEYTCRATNKWGSATT-TAKITCSAKRDIVLESQLPQGMSG 3805
              ++   +  D G+Y C A N++G   +  A+I  +   D  +  Q   G  G
Sbjct: 101  FRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEG 153



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 4/103 (3%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V QAP    Q         G +A + C+ +  P P+  V W  NG+VL  G   R  N+ 
Sbjct: 325  VVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPH--VTWLKNGQVLGPGGHVRLKNNN 382

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              + L I  +  ED   Y C A N+ G + +S RL V   E +
Sbjct: 383  --STLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGL 423



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   V+   +I  P G    F C+ +  G+P   + W  NG+    G  V   N+     
Sbjct: 329  PAEFVQHPQSISRPAGTTAMFTCQAQ--GEPPPHVTWLKNGQVLGPGGHVRLKNNNS--T 384

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            L I  I   D   Y C A N  GS+  +A++T
Sbjct: 385  LTISGIGPEDEAIYQCVAENSAGSSQASARLT 416



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 18/52 (34%), Positives = 25/52 (48%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            + P  FV  P +++   G  A F C+  G P P V WL NG  +  G   +L
Sbjct: 327  QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRL 378



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 5/105 (4%)

Query: 1699 RHSAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN 1757
            R +AQ  ++ QAP  F    + I       A F  +    G+P   V WL+NG  +    
Sbjct: 317  RRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQA--QGEPPPHVTWLKNGQVLGPGG 374

Query: 1758 RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             +   ++     L +  + PED   Y C A N  G +  S+ L V
Sbjct: 375  HVRLKNNNS--TLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 261 GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
           G    P I   P N  L     A  +   +GNPRP V+W +   R I     +++ T N 
Sbjct: 233 GAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGN- 291

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCI--VTSGYLAVESPTESYVQDQRS 368
             L + +     SG Y   A  P   +     G L V++P E +VQ  +S
Sbjct: 292 --LIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAE-FVQHPQS 338



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 33/104 (31%), Positives = 43/104 (41%), Gaps = 5/104 (4%)

Query: 56  GDRQPITA-GRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE 114
           G R   TA GR    +P  F Q  ++     G  A F  + +G P P V+W +    L  
Sbjct: 313 GTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGP 372

Query: 115 CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
                ++ N  T    L I  IGP DE  Y C A N  G +  S
Sbjct: 373 GGHVRLKNNNST----LTISGIGPEDEAIYQCVAENSAGSSQAS 412



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 5/81 (6%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            F Q  Q+I     G TA F C+    G+P   V W +N +++     +   ++    ++T
Sbjct: 332  FVQHPQSISR-PAGTTAMFTCQA--QGEPPPHVTWLKNGQVLGPGGHVRLKNNNS--TLT 386

Query: 2438 ISHVRDEDEGVYMCRASNLLG 2458
            IS +  EDE +Y C A N  G
Sbjct: 387  ISGIGPEDEAIYQCVAENSAG 407



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/90 (33%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 1446 FVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALD 1505
            FV  P+SI     G    F C+ +     +  V W KNGQ +  G   R  ++     L 
Sbjct: 332  FVQHPQSISRPA-GTTAMFTCQAQGEPPPH--VTWLKNGQVLGPGGHVRLKNNNS--TLT 386

Query: 1506 IIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            I  +  ED  IY C A N  G+ + S RLT
Sbjct: 387  ISGIGPEDEAIYQCVAENSAGSSQASARLT 416



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 4/88 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+ H  +I    G    F C  +   +P   + W  N + L  G   +  ++ S  +L I
Sbjct: 332  FVQHPQSISRPAGTTAMFTCQAQG--EPPPHVTWLKNGQVLGPGGHVRLKNNNS--TLTI 387

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            +    ED  IY C A NS GS+  S  L
Sbjct: 388  SGIGPEDEAIYQCVAENSAGSSQASARL 415



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILY---CYEENSGEYECVATNKLGR-DS 3367
            P +++ W  NG +LP         +  ++I            + G+YECVA N+ G   S
Sbjct: 69   PPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVS 128

Query: 3368 TKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398
             KA ++  +  +  +  Q   G EGG+ + Q
Sbjct: 129  RKARIQAATMSDFHVHPQATVGEEGGVARFQ 159



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 2638 VQQAPI-FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            V QAP  F  H +S  +   G       Q +    P+  + W KNG  L  G  ++   +
Sbjct: 325  VVQAPAEFVQHPQSISRPA-GTTAMFTCQAQGEPPPH--VTWLKNGQVLGPGGHVRLKNN 381

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                TL+I+ +  +D  IY C A N  G + ++A + +
Sbjct: 382  NS--TLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            V W  NG+ +     ++  ++     L I+ +  ED  +Y  VA N+AG +Q SA +TV
Sbjct: 361  VTWLKNGQVLGPGGHVRLKNNNS--TLTISGIGPEDEAIYQCVAENSAGSSQASARLTV 417



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 1/49 (2%)

Query: 4117 PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI-VNGSRYKLTYDGM 4164
            P A   EEG  ARF C++ G PKP + W  N   I  +  RY L   G+
Sbjct: 145  PQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGV 193



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 43/158 (27%), Positives = 65/158 (41%), Gaps = 16/158 (10%)

Query: 3076 GDQSMVIEWFYNGKTI-EASHRIRTVYAFGMVVLEIL----GTKTTDSGTYSCRATNKWG 3130
            G   + I W  NG  + E++H   T+ A G +++       G   +D G Y C A N++G
Sbjct: 67   GTPPVRITWRKNGVELPESTHS--TLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFG 124

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
               +S K      +      F  H Q   G ++G  A F+C +  +  P   I W  N  
Sbjct: 125  LV-VSRKARIQAATMSD---FHVHPQATVG-EEGGVARFQCQIHGLPKP--LITWEKNRV 177

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            P+       T+   G  VL I   +  D G + C A N
Sbjct: 178  PIDTDNERYTLLPKG--VLQITGLRAEDGGIFHCVASN 213



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/114 (25%), Positives = 41/114 (35%), Gaps = 10/114 (8%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A F C+ +    PH+T  W  NGQ +  G   R  ++     L I     ED   Y 
Sbjct: 344  GTTAMFTCQAQGEPPPHVT--WLKNGQVLGPGGHVRLKNNNS--TLTISGIGPEDEAIYQ 399

Query: 2184 CKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEP 2237
            C A N  G +  +  L V     +      P     +R +       R+   EP
Sbjct: 400  CVAENSAGSSQASARLTVLWAEGL------PGPPRNVRAVSVSSTEVRVSWSEP 447



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
           LG  +    A +P +     G       ++ G P  R+TW KNG  L  S    ++   +
Sbjct: 36  LGHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGS 95

Query: 320 HTTLRVR---NTQKSDSGHYTLLAENPNGCIVT 349
                 R       SD G Y  +A+N  G +V+
Sbjct: 96  LMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVS 128



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 15/169 (8%)

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121
            EG +A ++  +   G    +I W  N   I+  +   T+   G  VL+I G +  D G +
Sbjct: 152  EGGVARFQCQI--HGLPKPLITWEKNRVPIDTDNERYTLLPKG--VLQITGLRAEDGGIF 207

Query: 3122 SCRATNKWG-QAEISVKLECVDKSKG--QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
             C A+N    +     +L       G  ++P      +N+  L   Q+A  EC  V   +
Sbjct: 208  HCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLT-LTVHQTAVLEC--VATGN 264

Query: 3179 PDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            P   + W   +G+P+     I+ +     ++ D+  T  H SG YVC A
Sbjct: 265  PRPIVSWSRLDGRPI-GVEGIQVLGTGNLIISDV--TVQH-SGVYVCAA 309



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYV---NPEDSGTYTCRAINELGEA 1794
            G P +R+ W +NGV +  S   T + +   +  + +     +P D G Y C A N  G  
Sbjct: 67   GTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLV 126

Query: 1795 VT 1796
            V+
Sbjct: 127  VS 128



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            IS   G  A F  + +  G+    V WLK+G+ +     +    N     LTI  +   D
Sbjct: 339  ISRPAGTTAMFTCQAQ--GEPPPHVTWLKNGQVLGPGGHVRLKNNNS--TLTISGIGPED 394

Query: 979  AGHYTCRAYNAIGQATTSANLTIV 1002
               Y C A N+ G +  SA LT++
Sbjct: 395  EAIYQCVAENSAGSSQASARLTVL 418



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 4/66 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           +GG A+F+ ++ G P P+++W + + P+   N+   RY      V L I  +   D G +
Sbjct: 152 EGGVARFQCQIHGLPKPLITWEKNRVPIDTDNE---RYTLLPKGV-LQITGLRAEDGGIF 207

Query: 145 TCTARN 150
            C A N
Sbjct: 208 HCVASN 213


>DQ248309-1|ABB55264.1|  851|Homo sapiens rhabdomyosarcoma antigen
            MU-RMS-40.14 protein.
          Length = 851

 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 96/405 (23%), Positives = 174/405 (42%), Gaps = 52/405 (12%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F + +   +V E E ARFE E   E    +KW+++   IK    + I +     IL+I +
Sbjct: 357  FLRPLTDLQVREKEMARFECELSRENAK-VKWFKDGAEIKKGKKYDIISKGAVRILVINK 415

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              ++D A ++        TA+ S  L V E+            FT    N+ V+    ++
Sbjct: 416  CLLDDEAEYSCEVR----TARTSGMLTVLEEEAV---------FTKNLANIEVSETDTIK 462

Query: 4533 LDTKVTGTKP-IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            L  +V+  KP  +V W K  +++    R +IL E     L+I  A+ +D+G Y C     
Sbjct: 463  LVCEVS--KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC----- 515

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
                         LP+++   K   K      E I   ++  + EG+  EF C I  +  
Sbjct: 516  ------------RLPSSRTDGK--VKVHELAAEFISKPQNLEILEGEKAEFVCSISKESF 561

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV--AYNSAGRVTVAAK 4709
            P VQW + DK ++    + +     +  L + +A  +D G Y  +  A  +A  +TV  K
Sbjct: 562  P-VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEK 620

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            L++           + PL+D  V E Q   F  ++ ++     +W R    I ++  + +
Sbjct: 621  LRI-----------VVPLKDTRVKEQQEVVFNCEVNTE-GAKAKWFRNEEAIFDSSKYII 668

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVVKSK 4813
            + +     L I + + +D   +    T   G+ V+++A L+V+ +
Sbjct: 669  LQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEE 713



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 91/384 (23%), Positives = 165/384 (42%), Gaps = 44/384 (11%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF 4474
            + +    V E E ARFE E   + +    W  +   +  +PD +I        L++    
Sbjct: 92   RPLHSVEVMETETARFETEISEDDIHA-NWKLKGEALLQTPDCEIKEEGKIHSLVLHNCR 150

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            ++ +      A N     K SA+L V+ +      G++ P      ++V VT+G+    D
Sbjct: 151  LDQTGGVDFQAAN----VKSSAHLRVKPRVI----GLLRP-----LKDVTVTAGETATFD 197

Query: 4535 TKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE 4594
             +++  + I V W   GKK++P  +     E   +TL + +   +D+G+ +     +A +
Sbjct: 198  CELS-YEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQL----TAKD 252

Query: 4595 ARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
             +  A   V  P               P E  +PL+D+ V EG      C+ V +    V
Sbjct: 253  FKTHANLFVKEP---------------PVEFTKPLEDQTVEEGATAVLECE-VSRENAKV 296

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            +W+K    I  SK +++        L I +  PED   Y C A +       +  L V  
Sbjct: 297  KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKD----FKTSCNLNVVP 352

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
            P    ++  L PL D+ V E + A+F+ ++ S+    ++W ++GA I +   + +I +G 
Sbjct: 353  P----HVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGA 407

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTA 4798
              +L+I     +D   ++C   TA
Sbjct: 408  VRILVINKCLLDDEAEYSCEVRTA 431



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 89/359 (24%), Positives = 153/359 (42%), Gaps = 44/359 (12%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQ 4472
            F  K Q   + E E+A F      E  P ++W R++  +++   + +     K +L+++ 
Sbjct: 535  FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKRVLVVKD 593

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
              ++D   +  +     G A+ +A+L V EK R     IV P      ++  V   Q V 
Sbjct: 594  ATLQDMGTYVVMV----GAARAAAHLTVIEKLR-----IVVP-----LKDTRVKEQQEVV 639

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
             + +V  T+     W +N + +    +  IL++D  YTL I +A+  D   Y     N  
Sbjct: 640  FNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHR 698

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
            GE   + +   +L   ++  +           I+EPLKD    E +++ F CK V +   
Sbjct: 699  GE---NVKSAANLIVEEEDLR-----------IVEPLKDIETMEKKSVTFWCK-VNRLNV 743

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEY--TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
            T++W K  + +      ++S   D+Y   L I +    DEG+Y   A       +VA  L
Sbjct: 744  TLKWTKNGEEVPFDN--RVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDK---SVAELL 798

Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
             +  P +      +  L D  V E   A F  Q+ S+ K  ++W R G  I E    Q+
Sbjct: 799  IIEAPTE-----FVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKIQI 851



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 89/373 (23%), Positives = 153/373 (41%), Gaps = 52/373 (13%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E A F+ E   E +P ++WY +   ++ S      +      L +R V +ED+      A
Sbjct: 192  ETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTA 250

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
            ++     K  ANL V+E          P  FT   ++  V  G    L+ +V+  +   V
Sbjct: 251  KD----FKTHANLFVKEP---------PVEFTKPLEDQTVEEGATAVLECEVS-RENAKV 296

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W KNG ++    + +I+ +     L+I +  P+D   Y C A +   +  C+   V   
Sbjct: 297  KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSCNLNVV--- 351

Query: 4606 PATKDKPKPQTKAANAPP--EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
                            PP  E + PL D  V E +   F C++  +    V+W+K    I
Sbjct: 352  ----------------PPHVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEI 394

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS--AGRVTVAAKLKVTQPDQADNL 4721
            K  K + +        L I++   +DE +Y C    +  +G +TV  +  V   +     
Sbjct: 395  KKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKN----- 449

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
                 L +I V E    +   ++ SK    + W +    I ET  ++++ EG   +L+I 
Sbjct: 450  -----LANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 503

Query: 4782 NTYEEDTGTFTCR 4794
            N + ED G + CR
Sbjct: 504  NAHLEDAGNYNCR 516



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 96/405 (23%), Positives = 167/405 (41%), Gaps = 51/405 (12%)

Query: 4409 KPPI-FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +PP+ FTK ++   V E   A  E E   E    +KW++    I  S  ++I        
Sbjct: 263  EPPVEFTKPLEDQTVEEGATAVLECEVSRENAK-VKWFKNGTEILKSKKYEIVADGRVRK 321

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP--SFTLTAQNVNV 4525
            L+I     ED   +   A++     K S NL            +VPP   F     ++ V
Sbjct: 322  LVIHDCTPEDIKTYTCDAKD----FKTSCNL-----------NVVPPHVEFLRPLTDLQV 366

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
               ++ R + +++  +   V W K+G +++   +  I+ +     L+I +    D  +Y 
Sbjct: 367  REKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYS 425

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C       E R  A     L   +++       AN     IE      V+E   I+  C+
Sbjct: 426  C-------EVR-TARTSGMLTVLEEEAVFTKNLAN-----IE------VSETDTIKLVCE 466

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             V KP   V WYKGD+ I  +  +++     +  L I  A  ED G+Y C   +S     
Sbjct: 467  -VSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSS----R 521

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
               K+KV +         ++  +++ + EG+ A+F   I+ +  P +QW R+   +    
Sbjct: 522  TDGKVKVHEL----AAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGD 576

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCR--ATTAAGQVETSAKL 4808
             + +I +G   VL++ +   +D GT+     A  AA  +    KL
Sbjct: 577  KYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKL 621



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 48/196 (24%), Positives = 81/196 (41%), Gaps = 13/196 (6%)

Query: 373 DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
           D Q    +    +  K      ++  +D  VT G+   FDC ++    P V W++  +++
Sbjct: 158 DFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKL 216

Query: 433 RDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
               + K++    G  H L + +V L D+G V   A++      F+   N+  KE  V  
Sbjct: 217 EP--SDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD------FKTHANLFVKEPPV-- 266

Query: 492 KFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551
           +F +      V EG   VL    V     ++ W K+G  I+ + +  I  DG    L I 
Sbjct: 267 EFTKPLEDQTVEEGATAVLECE-VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIH 325

Query: 552 RAKASDAAWYQCTAQN 567
                D   Y C A++
Sbjct: 326 DCTPEDIKTYTCDAKD 341



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 51/185 (27%), Positives = 83/185 (44%), Gaps = 14/185 (7%)

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L+D    E   +   C+I     P V+W+K  K IKPSK   +     +  L + +A   
Sbjct: 5    LQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKS 63

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            D G Y C      G    + KL +   +    +  + PL  + V E + A+F+T+I S+ 
Sbjct: 64   DIGQYTC----DCGTDKTSGKLDIEDRE----IKLVRPLHSVEVMETETARFETEI-SED 114

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
                 W  +G  + +TPD ++  EG    L++ N   + TG    +    A  V++SA L
Sbjct: 115  DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQ----AANVKSSAHL 170

Query: 4809 VVKSK 4813
             VK +
Sbjct: 171  RVKPR 175



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 11/171 (6%)

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           +F++   D  V E +M RF+C ++ R   +V WF +  +I+    + I +++     L+I
Sbjct: 356 EFLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDI-ISKGAVRILVI 413

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
               L D    +C  R  +  T+    L V+E+E V    F +  + + V E + + L  
Sbjct: 414 NKCLLDDEAEYSCEVR--TARTSGM--LTVLEEEAV----FTKNLANIEVSETDTIKLVC 465

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             V  P   + W K    II      I T+G    L I  A   DA  Y C
Sbjct: 466 E-VSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 515



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 52/230 (22%), Positives = 93/230 (40%), Gaps = 15/230 (6%)

Query: 347 IVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEG 406
           I+T G   +     ++++D    Y        T+ ++++ E  LA +F+   Q+ ++ EG
Sbjct: 491 ILTEGRKRILVIQNAHLEDA-GNYNCRLPSSRTDGKVKVHE--LAAEFISKPQNLEILEG 547

Query: 407 KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
           +   F C ++   +P V W  +D+ +     + ++  +     L++ + TL D G    +
Sbjct: 548 EKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIA-DGKKRVLVVKDATLQDMGTYVVM 605

Query: 467 ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
                G       L VIEK ++V P          V+E + VV N   V T   +  W +
Sbjct: 606 V----GAARAAAHLTVIEKLRIVVP-----LKDTRVKEQQEVVFNCE-VNTEGAKAKWFR 655

Query: 527 DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           +   I  + +  I       TL I  A   D A Y  +  N  G     A
Sbjct: 656 NEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSA 705



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 11/179 (6%)

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           +F K  +D+ V EG     +C V+ R   +V WF N  +I     ++I V +     L+I
Sbjct: 267 EFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEI-VADGRVRKLVI 324

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
            + T  D    TC A  K  +T+  C LNV+        +F+   + L VRE E      
Sbjct: 325 HDCTPEDIKTYTCDA--KDFKTS--CNLNVVPPHV----EFLRPLTDLQVREKEMARFEC 376

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             +     ++ W KDG  I    +  I + G    L I +    D A Y C  +    S
Sbjct: 377 E-LSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTS 434



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 119/612 (19%), Positives = 236/612 (38%), Gaps = 50/612 (8%)

Query: 1174 KSKPV-FVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            K  PV F +PL +   V EG    LEC +        +V+WF NG  +    +++   D 
Sbjct: 262  KEPPVEFTKPLEDQT-VEEGATAVLECEVSR---ENAKVKWFKNGTEILKSKKYEIVAD- 316

Query: 1233 GFVALDIIH-ATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ---NEQAIEQI 1288
            G V   +IH  T  D   YT  A +   S + + +   +E    +TD Q    E A  + 
Sbjct: 317  GRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFEC 376

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
            +L  + A+  K  ++   + +  ++         +   N   +C L          E+ C
Sbjct: 377  ELSRENAK-VKWFKDGAEIKKGKKYDIISKGAVRILVIN---KCLLDD------EAEYSC 426

Query: 1349 NGKPIKTGHRFRPAYEFDYVALDL--LSVYPEDSGVYTCQATNQLGEAVTSCALRVI--- 1403
              +  +T        E      +L  + V   D+    C+ +    E +       I   
Sbjct: 427  EVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIET 486

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYK------KTDIIDESVTIKPRFVTRPKSIENVI 1457
             + +++ E +    + +  +LED   Y       +TD   +   +   F+++P+++E ++
Sbjct: 487  GRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLE-IL 545

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EG+   F C    ++  +  V+W ++ + +  G ++  I D     L + D   +D G Y
Sbjct: 546  EGEKAEFVCS---ISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 602

Query: 1518 TCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
                V +VG    +  LT      IV   ++    EQ +V+ +               + 
Sbjct: 603  ----VVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEE 658

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSD-ATLKVE-WYHNNKPLKSGSR-FTETNNFGF 1634
             I  +S K + +++        R   + D A   V    H  + +KS +    E  +   
Sbjct: 659  AIFDSS-KYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRI 717

Query: 1635 V-ALDIMSCLPEDSGTYTCRA--INALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN-Q 1690
            V  L  +  + + S T+ C+   +N   +   +G  +    +  Y   +++  L   +  
Sbjct: 718  VEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCG 777

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQ-AAHFEARLI--PVGDPKLRVEWL 1747
              D  +Y   + QD+ + +  +   P + +   E+Q    F+  +    +   K  V+W 
Sbjct: 778  FPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWY 837

Query: 1748 RNGVPIEASNRL 1759
            RNG  I+   ++
Sbjct: 838  RNGREIKEGKKI 849



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 90/360 (25%), Positives = 144/360 (40%), Gaps = 39/360 (10%)

Query: 1313 FSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDL 1372
            F+  L +   VE   V L+C +         V+WF +GK IK         +     L L
Sbjct: 1    FTGKLQDYTGVEKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKADGKKRMLIL 57

Query: 1373 LSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DTSRYK 1431
                  D G YTC      G   TS  L +   +D  ++   P  L  ++ +E +T+R++
Sbjct: 58   KKALKSDIGQYTCDC----GTDKTSGKLDI---EDREIKLVRP--LHSVEVMETETARFE 108

Query: 1432 KTDIIDESV----TIKPRFVTRPKSIENVIEGQ-H--VHFECKLEPVTD-----SNLKVE 1479
             T+I ++ +     +K   + +    E   EG+ H  V   C+L+         +N+K  
Sbjct: 109  -TEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSS 167

Query: 1480 WFKNGQPVTIGHRFRPIHDF----GYVALDIIDLIAEDSGI-YTCRAVNLVGTDEVSCRL 1534
                 +P  IG   RP+ D     G  A    +L  ED  + +  +   L  +D+V  R 
Sbjct: 168  AHLRVKPRVIG-LLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRS 226

Query: 1535 TCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
              +  T  +R  + E   E +Q+     K H    V E   +    T  L++  ++EG  
Sbjct: 227  EGKVHTLTLRDVKLEDAGE-VQLTAKDFKTHANLFVKEPPVEF---TKPLEDQTVEEGAT 282

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
            A  E     VS    KV+W+ N   +    ++    +     L I  C PED  TYTC A
Sbjct: 283  AVLE---CEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 339



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 80/392 (20%), Positives = 151/392 (38%), Gaps = 29/392 (7%)

Query: 910  EFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVAL 969
            EF  P++DQ +++EG  A  E     +     +V+W K+G  +  S +     +     L
Sbjct: 267  EFTKPLEDQ-TVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKL 322

Query: 970  TIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRY 1029
             I   T  D   YTC A +      TS NL +V       E   P    +++  E A   
Sbjct: 323  VIHDCTPEDIKTYTCDAKD----FKTSCNLNVVPPH---VEFLRPLTDLQVREKEMARFE 375

Query: 1030 SKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSA 1089
             + + E  K+          KG    +  + A     V  +  L    E+    +   ++
Sbjct: 376  CELSRENAKVKWFKDGAEIKKGKKYDIISKGA-VRILVINKCLLDDEAEYSCEVRTARTS 434

Query: 1090 NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL----SASMTVET-RSSIDTS 1144
              +    +      ++A++   ++    +V   +   A++         +ET R  I T 
Sbjct: 435  GMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTE 494

Query: 1145 SIHRGLYEKTRHIEESKFVE---PMYQIEEISKSKPVFVQPLSNPP--PVSEGKNIHLEC 1199
               R L  +  H+E++       P  + +   K   +  + +S P    + EG+     C
Sbjct: 495  GRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVC 554

Query: 1200 RLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLG 1259
             +     P   V+W  + +++  G ++    D     L +  AT  D G Y V     +G
Sbjct: 555  SISKESFP---VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VG 607

Query: 1260 SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL 1291
            +A  +A + VIE+  IV   ++ +  EQ +++
Sbjct: 608  AARAAAHLTVIEKLRIVVPLKDTRVKEQQEVV 639



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 58/268 (21%), Positives = 106/268 (39%), Gaps = 35/268 (13%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLIL-EAYPQDSGKYECVAINSAGEARCDAECVV 4603
            V W K+GK+++P  +N +++ DG   +LIL +A   D G+Y C             +C  
Sbjct: 29   VKWFKDGKEIKPS-KNAVIKADGKKRMLILKKALKSDIGQYTC-------------DC-- 72

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
                  DK   +    +   +++ PL    V E +   F  +I    +      KG+ L+
Sbjct: 73   ----GTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALL 128

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA 4723
            + +   ++      ++L +     +  G     A N      +  K +V        +  
Sbjct: 129  Q-TPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRV--------IGL 179

Query: 4724 LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNT 4783
            L PL+D+ V  G+ A F  +++ +  P ++W  +G  +  +       EG    L + + 
Sbjct: 180  LRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDV 238

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              ED G         A   +T A L VK
Sbjct: 239  KLEDAG----EVQLTAKDFKTHANLFVK 262



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 49/208 (23%), Positives = 91/208 (43%), Gaps = 24/208 (11%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V ++ G+ A ++  L     + + +EW+  GK +E S ++       +  L +   K  D
Sbjct: 186  VTVTAGETATFDCEL---SYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLED 242

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            +G     A +    A + VK   V+        FT  +++ + +++G +A  EC V    
Sbjct: 243  AGEVQLTAKDFKTHANLFVKEPPVE--------FTKPLED-QTVEEGATAVLECEV---S 290

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF-TR 3236
              + K++W+ NG  +  S + + V+D     L I      D   Y C A     +DF T 
Sbjct: 291  RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA-----KDFKTS 345

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELE 3264
              +N       ++E L+P +  ++RE E
Sbjct: 346  CNLNVVPP---HVEFLRPLTDLQVREKE 370



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 9/122 (7%)

Query: 3933 VPRGMKRSEALTQMEATIKKYTSEVYLTEDDLY---DVDKKQPP-RFVTQIQSQTSLVEM 3988
            VPR   +   LT  +  ++    EV LT  D     ++  K+PP  F   ++ QT + E 
Sbjct: 223  VPRSEGKVHTLTLRDVKLED-AGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQT-VEEG 280

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
             T   EC+   V   N KV+WF NG  +L   ++  + D     +      PED   Y C
Sbjct: 281  ATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 337

Query: 4049 RA 4050
             A
Sbjct: 338  DA 339



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 9/100 (9%)

Query: 2222 QLEAQGHSTRIE--VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
            QL A+   T     V+EP   P  F   L   T V EG TA  EC+V      N +++++
Sbjct: 247  QLTAKDFKTHANLFVKEP---PVEFTKPLEDQT-VEEGATAVLECEVSR---ENAKVKWF 299

Query: 2280 HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKA 2319
             NG  +  + ++ I  D     L I  C PED   Y+  A
Sbjct: 300  KNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 339



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 74/360 (20%), Positives = 140/360 (38%), Gaps = 39/360 (10%)

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM 1772
            FT  ++D    E      +  +     P   V+W ++G  I+ S       D     L +
Sbjct: 1    FTGKLQDYTGVEKDEVILQCEISKADAP---VKWFKDGKEIKPSKNAVIKADGKKRMLIL 57

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE-DSSRYQ 1831
            K     D G YTC    + G   TS  L ++ +     E +    L  ++ +E +++R++
Sbjct: 58   KKALKSDIGQYTC----DCGTDKTSGKLDIEDR-----EIKLVRPLHSVEVMETETARFE 108

Query: 1832 RR-EDVEVAVNQAPRFITQLNGPT-KLSEGQSAH----YECRIEPYPDPNMRVEWYFNGK 1885
                + ++  N   +    L  P  ++ E    H    + CR++     + +        
Sbjct: 109  TEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQA-----AN 163

Query: 1886 VLQSGHRYRTSNDFGFAA-LDILTVYGEDSGEYTCK-AINNLGQAVSSIRLNVQSKESII 1943
            V  S H        G    L  +TV   ++  + C+ +  ++          ++  + ++
Sbjct: 164  VKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVV 223

Query: 1944 RDSQ---HESALEKIQYLEDDSRYKRAVQD-----DSFVVEKP-QFGKPIKNAEVTEGHP 1994
              S+   H   L  ++ LED    +   +D     + FV E P +F KP+++  V EG  
Sbjct: 224  PRSEGKVHTLTLRDVK-LEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGAT 282

Query: 1995 VHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKA 2054
              LE  ++  N    +V+W+ NG  + +  +++   D     L I     ED  TY C A
Sbjct: 283  AVLECEVSREN---AKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 339



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 4/82 (4%)

Query: 1707 ITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + + PV FT P++D  V E   A  E     V     +V+W +NG  I  S +   + D 
Sbjct: 261  VKEPPVEFTKPLEDQTVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADG 317

Query: 1766 GYVALNMKYVNPEDSGTYTCRA 1787
                L +    PED  TYTC A
Sbjct: 318  RVRKLVIHDCTPEDIKTYTCDA 339



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 7/93 (7%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            P EFT    D  + E ++A  EC    V+  + +V+WF NG  +L   + + + D     
Sbjct: 265  PVEFTKPLEDQTVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRK 321

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L I      D   YTC A     +   SC L V
Sbjct: 322  LVIHDCTPEDIKTYTCDAK----DFKTSCNLNV 350



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 4/74 (5%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F  PL++++ +RE E A FE  L+     N KV+W+ +G  +K G ++         IL 
Sbjct: 357  FLRPLTDLQ-VREKEMARFECELSRE---NAKVKWFKDGAEIKKGKKYDIISKGAVRILV 412

Query: 3482 ISPTYPEDSGEYLC 3495
            I+    +D  EY C
Sbjct: 413  INKCLLDDEAEYSC 426



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 8/112 (7%)

Query: 1042 KPRFLG---PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            KPR +G   PLK    +  G++A F+  +  +    + VEWY  GK++  ++++    + 
Sbjct: 173  KPRVIGLLRPLKDVT-VTAGETATFDCELSYED---IPVEWYLKGKKLEPSDKVVPRSEG 228

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSA-SMTVETRSSIDTSSIHRG 1149
                L +  V+ ED+G   + A++    A L      VE    ++  ++  G
Sbjct: 229  KVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEG 280



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 40/181 (22%), Positives = 75/181 (41%), Gaps = 18/181 (9%)

Query: 3047 PP--EFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            PP  EF     D+  + E ++A +E  L     ++  ++WF +G  I+   +   +    
Sbjct: 352  PPHVEFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGA 407

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            + +L I      D   YSC          ++V LE       ++  FT ++ NIE + + 
Sbjct: 408  VRILVINKCLLDDEAEYSCEVRTARTSGMLTV-LE-------EEAVFTKNLANIE-VSET 458

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
             +    C V     P  ++ WY   + +  + R + +++    +L I      D+G Y C
Sbjct: 459  DTIKLVCEV---SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 515

Query: 3225 R 3225
            R
Sbjct: 516  R 516



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 8/122 (6%)

Query: 2336 AKGSIISESQRPEGLEKIRELE-SAEPFKRPEIPEPVTRQRPV-FTQPLQNIDNIQEGQT 2393
            ++G + + + R   LE   E++ +A+ FK         ++ PV FT+PL++   ++EG T
Sbjct: 226  SEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHA--NLFVKEPPVEFTKPLED-QTVEEGAT 282

Query: 2394 AHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453
            A  +C    V     KV+WF+N   I  S +     D     + I     ED   Y C A
Sbjct: 283  AVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 339

Query: 2454 SN 2455
             +
Sbjct: 340  KD 341



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 15/53 (28%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
            I+  P +F+  ++  TV E +   F C++  +   K  ++WYRNG+ +  G +
Sbjct: 799  IIEAPTEFVEHLEDQTVTEFDDAVFSCQLSRE---KANVKWYRNGREIKEGKK 848



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 5/86 (5%)

Query: 3826 VSTPP-KFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V  PP +F   ++  TVEE      EC V  +E+ K  ++W++NG  +    +Y  V D 
Sbjct: 261  VKEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAK--VKWFKNGTEILKSKKYEIVADG 317

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDF 3910
                L I     ED   Y C A  DF
Sbjct: 318  RVRKLVIHDCTPEDIKTYTCDA-KDF 342



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 60/258 (23%), Positives = 104/258 (40%), Gaps = 31/258 (12%)

Query: 89  AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCT 147
           A+FE +L       V W +  A + +  KY +      G V +L I +    DE EY+C 
Sbjct: 372 ARFECEL-SRENAKVKWFKDGAEIKKGKKYDII---SKGAVRILVINKCLLDDEAEYSCE 427

Query: 148 ARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKV 207
            R      + +V ++ E                 VSET       T     E S+   +V
Sbjct: 428 VRTARTSGMLTV-LEEEAVFTKNLANI------EVSET------DTIKLVCEVSKPGAEV 474

Query: 208 AYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEI--DRSLGPVSP 265
            +  G      D+  ++T  Y +L E   R  + +    E     +  +   R+ G V  
Sbjct: 475 IWYKG------DEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKV 528

Query: 266 PKIA----QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            ++A     KP+N ++ EG  A+F   +S    P V W ++ + L + +K+++I      
Sbjct: 529 HELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR 587

Query: 322 TLRVRNTQKSDSGHYTLL 339
            L V++    D G Y ++
Sbjct: 588 VLVVKDATLQDMGTYVVM 605



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V++ P+  T       + EG    LE +V      N K++WFKNG  +    + +   D 
Sbjct: 261  VKEPPVEFTKPLEDQTVEEGATAVLECEVSRE---NAKVKWFKNGTEILKSKKYEIVADG 317

Query: 2698 GLVTLSINSLRNDDSGIYTCKA 2719
             +  L I+    +D   YTC A
Sbjct: 318  RVRKLVIHDCTPEDIKTYTCDA 339



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 2380 QPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTIS 2439
            +PL+++  +  G+TA FDC L     P   VEW+   K +E S ++    +    ++T+ 
Sbjct: 181  RPLKDV-TVTAGETATFDCELSYEDIP---VEWYLKGKKLEPSDKVVPRSEGKVHTLTLR 236

Query: 2440 HVRDEDEG 2447
             V+ ED G
Sbjct: 237  DVKLEDAG 244



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 5/79 (6%)

Query: 3557 PP--EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            PP  EF    +DL + E   A FEC L   N    +V+WF +G  +  G +   I+    
Sbjct: 352  PPHVEFLRPLTDLQVREKEMARFECELSREN---AKVKWFKDGAEIKKGKKYDIISKGAV 408

Query: 3615 VILEIGGVYQRDAGLYTCK 3633
             IL I      D   Y+C+
Sbjct: 409  RILVINKCLLDDEAEYSCE 427



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)

Query: 4113 FVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            F+S P  + + EGE A F C ++    P V W  +  T+ +G +Y +  DG
Sbjct: 535  FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADG 584



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 71/337 (21%), Positives = 126/337 (37%), Gaps = 31/337 (9%)

Query: 1865 ECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINN 1924
            +C I     P   V+W+ +GK ++         D     L +      D G+YTC    +
Sbjct: 19   QCEISKADAP---VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----D 71

Query: 1925 LGQAVSSIRLNVQSKE-SIIRDSQHESALEKIQYLEDDS-RYKRAVQDDSFVVEKPQFGK 1982
             G   +S +L+++ +E  ++R       L  ++ +E ++ R++  + +D         G+
Sbjct: 72   CGTDKTSGKLDIEDREIKLVRP------LHSVEVMETETARFETEISEDDIHANWKLKGE 125

Query: 1983 PI---KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDI 2039
             +    + E+ E   +H         D T  V++           R K         L  
Sbjct: 126  ALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKD 185

Query: 2040 LYAYAEDTGTYMCKATNA--------VGEAVTTSSVKVDAKSG-LYLDTLDEQRLKKIQE 2090
            +   A +T T+ C+ +           G+ +  S   V    G ++  TL + +L+   E
Sbjct: 186  VTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGE 245

Query: 2091 LEKYERP-KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
            ++   +  K        + PV  T     + ++EG  A  EC V   N     + WF NG
Sbjct: 246  VQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSREN---AKVKWFKNG 302

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186
             +I    +Y    D     L I     ED  TY C A
Sbjct: 303  TEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 339



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 6/79 (7%)

Query: 3281 PP--KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            PP  +F+  + D+ ++ E + A FE  L      + KV+WF +G ++  G +Y       
Sbjct: 352  PPHVEFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGA 407

Query: 3339 IVILDILYCYEENSGEYEC 3357
            + IL I  C  ++  EY C
Sbjct: 408  VRILVINKCLLDDEAEYSC 426



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 5/78 (6%)

Query: 3829 PP--KFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            PP  +F+  +    V E E  RFEC +  +E+ K  ++W+++G  +  G +Y  +     
Sbjct: 352  PPHVEFLRPLTDLQVREKEMARFECELS-RENAK--VKWFKDGAEIKKGKKYDIISKGAV 408

Query: 3887 VSLDILYVYAEDSGEYIC 3904
              L I     +D  EY C
Sbjct: 409  RILVINKCLLDDEAEYSC 426



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 5/97 (5%)

Query: 1715 MPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMK 1773
            +P+KD RV E Q   F   +   G    + +W RN   I ++S  +    D  Y  L ++
Sbjct: 625  VPLKDTRVKEQQEVVFNCEVNTEG---AKAKWFRNEEAIFDSSKYIILQKDLVY-TLRIR 680

Query: 1774 YVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
              + +D   Y     N  GE V S+   +  +  L++
Sbjct: 681  DAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRI 717



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%)

Query: 4110 PPVFVSLP-DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            PPV  + P +  TVEEG  A   C V+     +V W  NG  I+   +Y++  DG
Sbjct: 264  PPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADG 317



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF  +L NI   E D I   C V     P  ++ W+  ++ +    RY+   +     L 
Sbjct: 445  VFTKNLANIEVSETDTIKLVCEVSK---PGAEVIWYKGDEEIIETGRYEILTEGRKRILV 501

Query: 2835 ITHTYEEDSGIYTCKATNSK 2854
            I + + ED+G Y C+  +S+
Sbjct: 502  IQNAHLEDAGNYNCRLPSSR 521



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 3/79 (3%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PP +F  PL+  T  EG     E     V     K++W KNG  I  S ++  +      
Sbjct: 264 PPVEFTKPLEDQTVEEGATAVLECE---VSRENAKVKWFKNGTEILKSKKYEIVADGRVR 320

Query: 695 SLDMLSLNIQDSGEYTCRA 713
            L +     +D   YTC A
Sbjct: 321 KLVIHDCTPEDIKTYTCDA 339



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 16/73 (21%), Positives = 38/73 (52%), Gaps = 1/73 (1%)

Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
           ++++++E  +  F  +++     +  WF+N + + +S+K+ I+      TLR+R+    D
Sbjct: 628 KDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDD 686

Query: 333 SGHYTLLAENPNG 345
             +Y +   N  G
Sbjct: 687 QANYNVSLTNHRG 699



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            FT PL + + + EG  A  E  ++     N KV+W+ NG  +    ++    D     L 
Sbjct: 268  FTKPLED-QTVEEGATAVLECEVSRE---NAKVKWFKNGTEILKSKKYEIVADGRVRKLV 323

Query: 3482 ISPTYPEDSGEYLCRA 3497
            I    PED   Y C A
Sbjct: 324  IHDCTPEDIKTYTCDA 339



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 771 QFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSL 830
           +F+RPL DL +++E   A FE +L   S    +V+W+KDG  I    +   I       L
Sbjct: 356 EFLRPLTDL-QVREKEMARFECEL---SRENAKVKWFKDGAEIKKGKKYDIISKGAVRIL 411

Query: 831 NIMHLRAEDAGSYT 844
            I     +D   Y+
Sbjct: 412 VINKCLLDDEAEYS 425



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 3/81 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L +   +EG     EC V  SR+   K++WF N   +    +Y+   D     L I
Sbjct: 268  FTKPLEDQTVEEGATAVLECEV--SRE-NAKVKWFKNGTEILKSKKYEIVADGRVRKLVI 324

Query: 2836 THTYEEDSGIYTCKATNSKGS 2856
                 ED   YTC A + K S
Sbjct: 325  HDCTPEDIKTYTCDAKDFKTS 345



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 16/135 (11%)

Query: 1824 LEDSSRYQ-----RREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMR 1877
            LED+  Y       R D +V V++ A  FI++     ++ EG+ A + C I     P   
Sbjct: 507  LEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQN-LEILEGEKAEFVCSISKESFP--- 562

Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY-----TCKAINNLGQAVSSI 1932
            V+W  + K L+SG +Y    D     L +     +D G Y       +A  +L   +  +
Sbjct: 563  VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHL-TVIEKL 621

Query: 1933 RLNVQSKESIIRDSQ 1947
            R+ V  K++ +++ Q
Sbjct: 622  RIVVPLKDTRVKEQQ 636



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 16/180 (8%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            ++I EG+ A +  S+     +S  ++W  + KT+E+  +   +      VL +      D
Sbjct: 542  LEILEGEKAEFVCSI---SKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQD 598

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             GTY        G A  +  L  ++K +   P   T +      K+ Q   F C    V+
Sbjct: 599  MGTYVVMV----GAARAAAHLTVIEKLRIVVPLKDTRV------KEQQEVVFNC---EVN 645

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
                K +W+ N + +  S++   +       L I      D   Y     N  GE+   A
Sbjct: 646  TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSA 705


>AK074780-1|BAC11205.1|  570|Homo sapiens protein ( Homo sapiens cDNA
            FLJ90299 fis, clone NT2RP2000514, highly similar to Homo
            sapiens roundabout 2 (robo2) mRNA. ).
          Length = 570

 Score = 94.3 bits (224), Expect = 1e-17
 Identities = 76/238 (31%), Positives = 107/238 (44%), Gaps = 22/238 (9%)

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D G Y C+A N  G+    A   V       + +P      APP+ +   +D+IVA+G+ 
Sbjct: 4    DEGTYMCIAENRVGKMEASATLTV-------RARPV-----APPQFVVRPRDQIVAQGRT 51

Query: 4640 IEFSCKIVGKPLPTVQWYK--GDKLIKPSKYFQ-MSRTADEYT--LRISEAFPEDEGDYK 4694
            + F C+  G P P V W K     L+ P++  Q  SR +   T  L I+     D G Y 
Sbjct: 52   VTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI 111

Query: 4695 CVAYNSAGRVTVAAKLKVTQ--PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
            C A   AG +   A+L+VT    D+   +    P    +  +G  A  K + T    P I
Sbjct: 112  CQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDG-TALLKCKATGDPLPVI 170

Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             WL+EG   P       I E     L I N    DTGT+TC AT+++G+   SA L V
Sbjct: 171  SWLKEGFTFPGRDPRATIQE--QGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 226



 Score = 84.6 bits (200), Expect = 8e-15
 Identities = 75/284 (26%), Positives = 117/284 (41%), Gaps = 30/284 (10%)

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D   +  +AENR G  + SA L V  +       + PP F +  ++  V  G+ V    +
Sbjct: 4    DEGTYMCIAENRVGKMEASATLTVRARP------VAPPQFVVRPRDQIVAQGRTVTFPCE 57

Query: 4537 VTGTKPIDVYWLKNGKKV-----QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
              G     V+W K G +      QP   N       T  L I      D+G Y C A+  
Sbjct: 58   TKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTV 117

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLKDKIVAEGQAIEFSCKIVGKP 4650
            AG     A+  V+   T D+P         PP I++ P    +  +G A+   CK  G P
Sbjct: 118  AGSILAKAQLEVTDVLT-DRP---------PPIILQGPANQTLAVDGTAL-LKCKATGDP 166

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
            LP + W K +    P +    +   ++ TL+I      D G Y CVA +S+G  + +A L
Sbjct: 167  LPVISWLK-EGFTFPGRD-PRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVL 224

Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
             VT+         ++   D+    G P++ +    +K   T+ W
Sbjct: 225  DVTESG-----ATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW 263



 Score = 71.3 bits (167), Expect = 8e-11
 Identities = 63/237 (26%), Positives = 107/237 (45%), Gaps = 35/237 (14%)

Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG-QRLINSNKHEIITTHNH 320
           PV+PP+   +PR+  + +G    F  +  GNP+P V W K G Q L+  N+ +   +   
Sbjct: 31  PVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCS 90

Query: 321 TT----LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
            +    L + N Q+SD+G+Y   A      +  +G +  ++  E          +TD   
Sbjct: 91  VSPTGDLTITNIQRSDAGYYICQA------LTVAGSILAKAQLE----------VTDVL- 133

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
             T+    I  +  A Q + V    D T        C+ TG P P ++W + +       
Sbjct: 134 --TDRPPPIILQGPANQTLAV----DGT----ALLKCKATGDPLPVISW-LKEGFTFPGR 182

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
           + +  + E G   L I N+ +SD+G  TCVA + SGET++   L+V E    ++  +
Sbjct: 183 DPRATIQEQGT--LQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNY 237



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 55/195 (28%), Positives = 82/195 (42%), Gaps = 13/195 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ------IRDDYNHKILVNES 445
           PQFV   +D+ V +G+   F C   G P P V W     Q           N +  V+ +
Sbjct: 35  PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 94

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVRE 504
           G+  L ITN+  SD+G   C A   +G    + +L V +       P  ++  +   +  
Sbjct: 95  GD--LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAV 152

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPII-PNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
               +L  +A G P P I+W K+G      +P   I   G   TL I   + SD   Y C
Sbjct: 153 DGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG---TLQIKNLRISDTGTYTC 209

Query: 564 TAQNVAGSTATRARL 578
            A + +G T+  A L
Sbjct: 210 VATSSSGETSWSAVL 224



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 40/126 (31%), Positives = 56/126 (44%), Gaps = 6/126 (4%)

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           +D G   C+A N+ G+      L V     V  P+FV R     V +G  V       G 
Sbjct: 3   TDEGTYMCIAENRVGKMEASATLTV-RARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGN 61

Query: 518 PTPRITWQKDGVP--IIPNPELRIHTDGGAS---TLDIPRAKASDAAWYQCTAQNVAGST 572
           P P + WQK+G    + PN   + ++    S    L I   + SDA +Y C A  VAGS 
Sbjct: 62  PQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSI 121

Query: 573 ATRARL 578
             +A+L
Sbjct: 122 LAKAQL 127



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 7/104 (6%)

Query: 635 PPPQFIV-PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
           PPP  +  P     A++G  +    + +  GDP   I WLK G +        +I   G 
Sbjct: 137 PPPIILQGPANQTLAVDGTAL---LKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG- 192

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR-ATIER 736
            +L + +L I D+G YTC A S++G     AVL VT   ATI +
Sbjct: 193 -TLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISK 235



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 5/109 (4%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP I Q P N  L     A  + + +G+P P ++W K G       +    T     TL+
Sbjct: 138 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEG--FTFPGRDPRATIQEQGTLQ 195

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
           ++N + SD+G YT +A + +G    + + AV   TES     ++  ++D
Sbjct: 196 IKNLRISDTGTYTCVATSSSG---ETSWSAVLDVTESGATISKNYDLSD 241



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 57/241 (23%), Positives = 83/241 (34%), Gaps = 14/241 (5%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYREN-----FPIKNSPDFQIH 4460
            +P  PP F  + +   V +     F  E  G P P + W +E      FP +        
Sbjct: 30   RPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRC 89

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
            + S    L I  +   D+  +   A    G+    A L V +          PP      
Sbjct: 90   SVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDR----PPPIILQGP 145

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580
             N  +       L  K TG     + WLK G           ++E G  TL I      D
Sbjct: 146  ANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISD 203

Query: 4581 SGKYECVAINSAGEARCDAEC-VVSLPATKDKPKPQTKAANAP--PEIIEPLKDKIVAEG 4637
            +G Y CVA +S+GE    A   V    AT  K    +     P  P++ +  K+ +    
Sbjct: 204  TGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW 263

Query: 4638 Q 4638
            Q
Sbjct: 264  Q 264



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PPI  Q   N   A  G A  + K  G+P PV+SW ++       +  +    + T    
Sbjct: 138 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT---- 193

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L IK +   D G YTC A +  GE   S  +
Sbjct: 194 LQIKNLRISDTGTYTCVATSSSGETSWSAVL 224



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 15/133 (11%)

Query: 3115 TTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174
            +TD GTY C A N+ G+ E S  L  V       P+F    ++ + +  G++  F C   
Sbjct: 2    STDEGTYMCIAENRVGKMEASATL-TVRARPVAPPQFVVRPRD-QIVAQGRTVTFPCET- 58

Query: 3175 PVDDPDMKIEWYHNG--------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               +P   + W   G        QP + ++R  +VS  G   L I   Q  D+G Y+C+A
Sbjct: 59   -KGNPQPAVFWQKEGSQNLLFPNQPQQPNSRC-SVSPTG--DLTITNIQRSDAGYYICQA 114

Query: 3227 YNKYGEDFTRATI 3239
                G    +A +
Sbjct: 115  LTVAGSILAKAQL 127



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDP   + WL+ G      +   T+ + G   L +K +   D+GTYTC A +  GE   S
Sbjct: 164  GDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSWS 221

Query: 1798 STLFV 1802
            + L V
Sbjct: 222  AVLDV 226



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TGD   VI W   G T        T+   G   L+I   + +D+GTY+C AT+  G+   
Sbjct: 163  TGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSW 220

Query: 3135 SVKLECVD 3142
            S  L+  +
Sbjct: 221  SAVLDVTE 228



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DP   I W K G T   G   ++T      TL I +LR  D+G YTC AT+  GE   +A
Sbjct: 165  DPLPVISWLKEGFTFP-GRDPRATIQ-EQGTLQIKNLRISDTGTYTCVATSSSGETSWSA 222

Query: 2731 SIKIED 2736
             + + +
Sbjct: 223  VLDVTE 228



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 5/124 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD    + WLK+G          T    G   L IK++ + D G YTC A ++ G+ + S
Sbjct: 164  GDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSSGETSWS 221

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIV 1056
            A L +      I+++     L  +       + +  T+  V ++ +P   G L  +  I+
Sbjct: 222  AVLDVTESGATISKNY---DLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYII 278

Query: 1057 EGQS 1060
            E  S
Sbjct: 279  EAFS 282



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 13/106 (12%)

Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG--------QSIEASS 683
           R   PPQF+V  +     +G  + F    E  G+P   + W K G        Q  + +S
Sbjct: 30  RPVAPPQFVVRPRDQIVAQGRTVTFPC--ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNS 87

Query: 684 RFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           R  S+   G   L + ++   D+G Y C+A++  G    KA L VT
Sbjct: 88  R-CSVSPTG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVT 130



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 16/114 (14%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK---LLPSGHRYR----TV 3881
            PP+F+ + +   V +   V F C  E K +P+  + W + G    L P+  +      +V
Sbjct: 34   PPQFVVRPRDQIVAQGRTVTFPC--ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSV 91

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL-----PDIILQ 3930
               G   L I  +   D+G YIC+A+   G    KA +    +     P IILQ
Sbjct: 92   SPTG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQ 143



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/108 (27%), Positives = 45/108 (41%), Gaps = 7/108 (6%)

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG-KPLLTGSR 3605
            TLT  A    PP+F   P D I+++  +  F C      +    V W   G + LL  ++
Sbjct: 24   TLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCE--TKGNPQPAVFWQKEGSQNLLFPNQ 81

Query: 3606 VKTINDFGFVI----LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             +  N    V     L I  + + DAG Y C+A    G      +L+V
Sbjct: 82   PQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 129



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 4086 KIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWL 4145
            ++ +MEAS  +T       ++   PP FV  P    V +G    F C   G+P+P V W 
Sbjct: 15   RVGKMEASATLTVR-----ARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQ 69

Query: 4146 LNGN 4149
              G+
Sbjct: 70   KEGS 73



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 4/93 (4%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP     P++  L+ + +A  +C+     D    + W   G          TI + G   
Sbjct: 138  PPIILQGPANQTLAVDGTALLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG--T 193

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L+I  +   D G YTC AT+  GE + S  L V
Sbjct: 194  LQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 226



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 39/180 (21%), Positives = 61/180 (33%), Gaps = 10/180 (5%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   + +D+G Y C+A    G      +LE  D    + P         + L    +A
Sbjct: 97   LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTA 156

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
              +C      DP   I W   G          T+ + G   L I   +  D+G Y C A 
Sbjct: 157  LLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVAT 212

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQ------PDSLAKIRELESLQGAQQQTPSTPSAEP 3281
            +  GE    A ++    G    ++        P S  ++ ++          P TP   P
Sbjct: 213  SSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLP 272



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 4/90 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP   ++   N  +   G     C+    GDP   I W   G  F       T+ + G  
Sbjct: 137  PPPIILQGPANQTLAVDGTALLKCKA--TGDPLPVISWLKEGFTFPGRDPRATIQEQG-- 192

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
             L I  +   D G YTC AT+  G  + +A
Sbjct: 193  TLQIKNLRISDTGTYTCVATSSSGETSWSA 222


>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
          Length = 1461

 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 83/321 (25%), Positives = 133/321 (41%), Gaps = 26/321 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT + +P  V+    A    E + + +P ++W +   P+    D  I   S   +L+I
Sbjct: 152  PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLD-DRVIKLPS--GMLVI 208

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                  D  ++  V E+ GG  K S    VE K       I    F      +    GQ 
Sbjct: 209  SNATEGDGGLYRCVVES-GGPPKYSDE--VELKVLPDPEVISDLVFLKQPSPLVRVIGQD 265

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            V L    +G     + W+KN + +  +   +++   G  +L I +    D+G Y C+A N
Sbjct: 266  VVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADN 324

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
                    AE  V                 A PE ++   +    E   I F C++ GKP
Sbjct: 325  GNETIEAQAELTVQ----------------AQPEFLKQPTNIYAHESMDIVFECEVTGKP 368

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             PTV+W K   ++ PS YF++ +   E+ L++      DEG Y+C+A N  G     A+L
Sbjct: 369  TPTVKWVKNGDMVIPSDYFKIVK---EHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQL 425

Query: 4711 KVTQPDQADNLPALTPLRDIV 4731
             + +   A   P  +  RD+V
Sbjct: 426  IILEHAPATTGPLPSAPRDVV 446



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 97/380 (25%), Positives = 161/380 (42%), Gaps = 37/380 (9%)

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE----DSAVFAAVA--ENRGG 4490
            EP P I+W ++   +    D +       S+ I   V  +    D   +  VA  E+ G 
Sbjct: 79   EPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGT 138

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKN 4550
                +A L+V         G+  P FT   +  +V +G    L+ +V       V W +N
Sbjct: 139  IISRTAKLIV--------AGL--PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQN 188

Query: 4551 GKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
             + +  D R   L       L+I  A   D G Y CV + S G  +   E  V L   K 
Sbjct: 189  RQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCV-VESGGPPKYSDE--VEL---KV 239

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             P P+  +     +   PL   I   GQ +   C   G P PT++W K ++ +      +
Sbjct: 240  LPDPEVISDLVFLKQPSPLVRVI---GQDVVLPCVASGLPTPTIKWMKNEEALDTESSER 296

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +   A   +L IS+   +D G Y C+A N  G  T+ A+ ++T   Q + L   T   +I
Sbjct: 297  LVLLAGG-SLEISDVTEDDAGTYFCIADN--GNETIEAQAELTVQAQPEFLKQPT---NI 350

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
              +E     F+ ++T K  PT++W++ G ++  +  F+++ E N  VL      + D G 
Sbjct: 351  YAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVL---GLVKSDEGF 407

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A    G  +  A+L++
Sbjct: 408  YQCIAENDVGNAQAGAQLII 427



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 44/166 (26%), Positives = 80/166 (48%), Gaps = 10/166 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  +G P P + W  N+  +  + + ++++   G+  L I++VT  D+G   C+A N + 
Sbjct: 270 CVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTEDDAGTYFCIADNGNE 327

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
               Q  L V  +     P+F+++ + +   E   +V      G PTP + W K+G  +I
Sbjct: 328 TIEAQAELTVQAQ-----PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVI 382

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P+   +I  +     L + +   SD  +YQC A+N  G+    A+L
Sbjct: 383 PSDYFKIVKEHNLQVLGLVK---SDEGFYQCIAENDVGNAQAGAQL 425



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
           E    L   + P+  ++P N    E  D  F+ +++G P P V W KNG  +I S+  +I
Sbjct: 330 EAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKI 389

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           +  HN   L+V    KSD G Y  +AEN  G
Sbjct: 390 VKEHN---LQVLGLVKSDEGFYQCIAENDVG 417



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 52/189 (27%), Positives = 81/189 (42%), Gaps = 7/189 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+F    +   V  G     +C V     P V W  N + +  D   +++   SG   L+
Sbjct: 152 PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLD--DRVIKLPSG--MLV 207

Query: 452 ITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPK-FVERFSTLNVREGEPVV 509
           I+N T  D G+  CV  +    + + +  L V+   +V++   F+++ S L    G+ VV
Sbjct: 208 ISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVV 267

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L   A G PTP I W K+   +      R+    G S L+I      DA  Y C A N  
Sbjct: 268 LPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS-LEISDVTEDDAGTYFCIADNGN 326

Query: 570 GSTATRARL 578
            +   +A L
Sbjct: 327 ETIEAQAEL 335



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 13/141 (9%)

Query: 347 IVTSGYLAVESPTESYVQDQRSQY--ITDTQQRETEERIEISEKALAPQFVKVCQDRDVT 404
           ++  G L +   TE    D    Y  I D      E + E++ +A  P+F+K   +    
Sbjct: 299 LLAGGSLEISDVTE----DDAGTYFCIADNGNETIEAQAELTVQA-QPEFLKQPTNIYAH 353

Query: 405 EGKMTRFDCRVTGRPYPEVTWFIN-DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV 463
           E     F+C VTG+P P V W  N D  I  DY  KI V E   H L +  +  SD G  
Sbjct: 354 ESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDY-FKI-VKE---HNLQVLGLVKSDEGFY 408

Query: 464 TCVARNKSGETAFQCRLNVIE 484
            C+A N  G      +L ++E
Sbjct: 409 QCIAENDVGNAQAGAQLIILE 429



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 67/280 (23%), Positives = 120/280 (42%), Gaps = 34/280 (12%)

Query: 4545 VYWLKNGK--KVQPDIRNKILEEDGTYTLLILEAYPQ--DSGKYECVA-INSAGE--ARC 4597
            + W K+G    +  D R ++L +   +   ++ +     D G Y+CVA + S G   +R 
Sbjct: 84   IEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRT 143

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
                V  LP    +P+P +                + A   AI  +C++    +P V+W 
Sbjct: 144  AKLIVAGLPRFTSQPEPSS----------------VYAGNNAI-LNCEVNADLVPFVRWE 186

Query: 4658 KGDK-LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG-RVTVAAKLKVT-Q 4714
            +  + L+   +  ++        L IS A   D G Y+CV  +    + +   +LKV   
Sbjct: 187  QNRQPLLLDDRVIKLPSGM----LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPD 242

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGALIPETPDFQMIHEG 4773
            P+   +L  L     +V   GQ        +    PTI+W++ E AL  E+ +  ++  G
Sbjct: 243  PEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAG 302

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +  L I +  E+D GT+ C A      +E  A+L V+++
Sbjct: 303  GS--LEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ 340



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 5/113 (4%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + D    T + + ++TV   P+F +   NI   E  ++  EC +   G  T  V+W  NG
Sbjct: 321  IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNG 378

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
              +     F+   E +   L +L +   D G Y C A N +G A     L ++
Sbjct: 379  DMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIIL 428



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 45/159 (28%), Positives = 62/159 (38%), Gaps = 12/159 (7%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            + +G  +  I+W  N + ++     R V   G   LEI      D+GTY C A N  G  
Sbjct: 271  VASGLPTPTIKWMKNEEALDTESSERLVLLAGGS-LEISDVTEDDAGTYFCIADN--GNE 327

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
             I  + E   ++   +P F     NI    +     FEC V     P +K  W  NG  +
Sbjct: 328  TIEAQAELTVQA---QPEFLKQPTNIYA-HESMDIVFECEVTGKPTPTVK--WVKNGDMV 381

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              S   K V +    VL +      D G Y C A N  G
Sbjct: 382  IPSDYFKIVKEHNLQVLGLV---KSDEGFYQCIAENDVG 417



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 5/76 (6%)

Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG--VPIIPNPELRIHTDGGASTLDIP 551
           VE   TL+VR G  V+LN  A   P+P+I W+KDG  + ++ +   ++  DG     ++ 
Sbjct: 57  VEPVDTLSVR-GSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVV 115

Query: 552 RAKAS--DAAWYQCTA 565
            +K +  D  +YQC A
Sbjct: 116 HSKHNKPDEGYYQCVA 131



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            + G  +   + E  V   P+F+ Q  +    ES  + FEC V  K  P   ++W +NG +
Sbjct: 323  DNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTP--TVKWVKNGDM 380

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            +     ++ V +    +L +L +   D G Y C A ND G
Sbjct: 381  VIPSDYFKIVKEH---NLQVLGLVKSDEGFYQCIAENDVG 417



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 6/96 (6%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V  +P F+ +P +I    E   + FEC++       +K  W KNG  V     F+ + +
Sbjct: 336  TVQAQPEFLKQPTNIY-AHESMDIVFECEVTGKPTPTVK--WVKNGDMVIPSDYFKIVKE 392

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                 L ++ L+  D G Y C A N VG  +   +L
Sbjct: 393  HN---LQVLGLVKSDEGFYQCIAENDVGNAQAGAQL 425



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 5/100 (5%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
           V   P+F+    ++ A E   I FE  +   G PT  ++W+KNG  +  S  F  +    
Sbjct: 337 VQAQPEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFKIVKEH- 393

Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
             +L +L L   D G Y C A +  G A+  A L +   A
Sbjct: 394 --NLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHA 431



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            PEF   P+++   E+    FEC +      +  V+W  NG  ++     K + +    +L
Sbjct: 341  PEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVL 398

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
               G+ + D G Y C A N  G A    +L
Sbjct: 399  ---GLVKSDEGFYQCIAENDVGNAQAGAQL 425



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/112 (23%), Positives = 44/112 (39%), Gaps = 2/112 (1%)

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            E   +  P F+  P  +   E     F C VTG P P V W+ NG+ ++    +K+  + 
Sbjct: 334  ELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKE- 392

Query: 4164 MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
             ++  +    + D G  + I             L ++       G L +APR
Sbjct: 393  -HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPR 443



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 44/176 (25%), Positives = 76/176 (43%), Gaps = 17/176 (9%)

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK--PSKYFQMSRTADEYTLRI 4682
            ++EP+ D +   G ++  +C    +P P ++W K    +        Q+      +   +
Sbjct: 56   LVEPV-DTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNV 114

Query: 4683 --SEAFPEDEGDYKCVA-YNSAGR-VTVAAKLKVTQPDQADNLPALTPLRD-IVVYEGQP 4737
              S+    DEG Y+CVA   S G  ++  AKL V        LP  T   +   VY G  
Sbjct: 115  VHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVA------GLPRFTSQPEPSSVYAGNN 168

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            A    ++ + + P ++W  E    P   D ++I +  + +L+I N  E D G + C
Sbjct: 169  AILNCEVNADLVPFVRW--EQNRQPLLLDDRVI-KLPSGMLVISNATEGDGGLYRC 221



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)

Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            Q E   +++P F++  +N     E  +I  EC  E  G PT  V+W  NG  V     FK
Sbjct: 332  QAELTVQAQPEFLKQPTNIY-AHESMDIVFEC--EVTGKPTPTVKWVKNGDMVIPSDYFK 388

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT 1277
               +     L ++    +D G Y   A N +G+A   A + ++E +   T
Sbjct: 389  IVKEHN---LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATT 435



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/141 (23%), Positives = 57/141 (40%), Gaps = 10/141 (7%)

Query: 1796 TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTK 1855
            +S  L + +  SL++    E        + D+         E+ V   P F+ Q   PT 
Sbjct: 293  SSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQ---PTN 349

Query: 1856 L--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
            +   E     +EC +   P P   V+W  NG ++     ++   +     L +L +   D
Sbjct: 350  IYAHESMDIVFECEVTGKPTPT--VKWVKNGDMVIPSDYFKIVKEHN---LQVLGLVKSD 404

Query: 1914 SGEYTCKAINNLGQAVSSIRL 1934
             G Y C A N++G A +  +L
Sbjct: 405  EGFYQCIAENDVGNAQAGAQL 425



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 1/81 (1%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
           G D       SG P P + W KN + L   +   ++      +L + +  + D+G Y  +
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAG-GSLEISDVTEDDAGTYFCI 321

Query: 340 AENPNGCIVTSGYLAVESPTE 360
           A+N N  I     L V++  E
Sbjct: 322 ADNGNETIEAQAELTVQAQPE 342



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 5/88 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+    NI   E  +I FEC V     PT+K  W  N   +     +K   +    +L +
Sbjct: 343  FLKQPTNIYAHESMDIVFECEVTGKPTPTVK--WVKNGDMVIPSDYFKIVKEH---NLQV 397

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                + D G Y C A N  G+A     L
Sbjct: 398  LGLVKSDEGFYQCIAENDVGNAQAGAQL 425



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 5/65 (7%)

Query: 91  FEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARN 150
           FE ++ G PTP V W  K   +V  + Y     E    V  L+K     DEG Y C A N
Sbjct: 360 FECEVTGKPTPTVKWV-KNGDMVIPSDYFKIVKEHNLQVLGLVK----SDEGFYQCIAEN 414

Query: 151 QYGEA 155
             G A
Sbjct: 415 DVGNA 419



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 5/104 (4%)

Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNG 2017
            + D+       Q +  V  +P+F K   N    E   +  E  +T    PT  V+W  NG
Sbjct: 321  IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVT--GKPTPTVKWVKNG 378

Query: 2018 RPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEA 2061
              V     FK   +     L +L     D G Y C A N VG A
Sbjct: 379  DMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVGNA 419



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/106 (27%), Positives = 45/106 (42%), Gaps = 6/106 (5%)

Query: 1702 AQDEVITQA-PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            AQ E+  QA P F     +I   E+    FE  +   G P   V+W++NG  +  S+   
Sbjct: 331  AQAELTVQAQPEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFK 388

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             + +     L +      D G Y C A N++G A   + L +   A
Sbjct: 389  IVKEHNLQVLGLV---KSDEGFYQCIAENDVGNAQAGAQLIILEHA 431



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/113 (25%), Positives = 50/113 (44%), Gaps = 4/113 (3%)

Query: 1446 FVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALD 1505
            F+ +P  +  VI GQ V   C    +    +K  W KN + +      R +   G  +L+
Sbjct: 251  FLKQPSPLVRVI-GQDVVLPCVASGLPTPTIK--WMKNEEALDTESSERLVLLAGG-SLE 306

Query: 1506 IIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVL 1558
            I D+  +D+G Y C A N   T E    LT ++  + ++   N    E + ++
Sbjct: 307  ISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV 359



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 10/92 (10%)

Query: 2369 EPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI--EDSSRIT 2426
            E   + +P F +   NI    E     F+C +   G PT  V+W +N  ++   D  +I 
Sbjct: 334  ELTVQAQPEFLKQPTNI-YAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFKIV 390

Query: 2427 KTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            K H+   + +  S     DEG Y C A N +G
Sbjct: 391  KEHNLQVLGLVKS-----DEGFYQCIAENDVG 417



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)

Query: 2367 IPEPVTRQRPVFT-QPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI 2425
            +P+P      VF  QP   +  I  GQ     C  +  G PT  ++W +NE+ ++  S  
Sbjct: 240  LPDPEVISDLVFLKQPSPLVRVI--GQDVVLPC--VASGLPTPTIKWMKNEEALDTESSE 295

Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
                  G  S+ IS V ++D G Y C A N
Sbjct: 296  RLVLLAGG-SLEISDVTEDDAGTYFCIADN 324



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 1/65 (1%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G PT  I+W+KN ++++  S    +   G  SL++  +   D+G Y C A +     E +
Sbjct: 274 GLPTPTIKWMKNEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADNGNETIEAQ 332

Query: 724 AVLHV 728
           A L V
Sbjct: 333 AELTV 337



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  +  ++W  NG  +  S   + V       L++LG   +D G Y C A N  G A+ 
Sbjct: 365  TGKPTPTVKWVKNGDMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVGNAQA 421

Query: 3135 SVKL 3138
              +L
Sbjct: 422  GAQL 425


>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chicken)
            protein.
          Length = 1461

 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 83/321 (25%), Positives = 133/321 (41%), Gaps = 26/321 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT + +P  V+    A    E + + +P ++W +   P+    D  I   S   +L+I
Sbjct: 152  PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLD-DRVIKLPS--GMLVI 208

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                  D  ++  V E+ GG  K S    VE K       I    F      +    GQ 
Sbjct: 209  SNATEGDGGLYRCVVES-GGPPKYSDE--VELKVLPDPEVISDLVFLKQPSPLVRVIGQD 265

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            V L    +G     + W+KN + +  +   +++   G  +L I +    D+G Y C+A N
Sbjct: 266  VVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADN 324

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
                    AE  V                 A PE ++   +    E   I F C++ GKP
Sbjct: 325  GNETIEAQAELTVQ----------------AQPEFLKQPTNIYAHESMDIVFECEVTGKP 368

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             PTV+W K   ++ PS YF++ +   E+ L++      DEG Y+C+A N  G     A+L
Sbjct: 369  TPTVKWVKNGDMVIPSDYFKIVK---EHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQL 425

Query: 4711 KVTQPDQADNLPALTPLRDIV 4731
             + +   A   P  +  RD+V
Sbjct: 426  IILEHAPATTGPLPSAPRDVV 446



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 97/380 (25%), Positives = 161/380 (42%), Gaps = 37/380 (9%)

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE----DSAVFAAVA--ENRGG 4490
            EP P I+W ++   +    D +       S+ I   V  +    D   +  VA  E+ G 
Sbjct: 79   EPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGT 138

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKN 4550
                +A L+V         G+  P FT   +  +V +G    L+ +V       V W +N
Sbjct: 139  IISRTAKLIV--------AGL--PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQN 188

Query: 4551 GKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
             + +  D R   L       L+I  A   D G Y CV + S G  +   E  V L   K 
Sbjct: 189  RQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCV-VESGGPPKYSDE--VEL---KV 239

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             P P+  +     +   PL   I   GQ +   C   G P PT++W K ++ +      +
Sbjct: 240  LPDPEVISDLVFLKQPSPLVRVI---GQDVVLPCVASGLPTPTIKWMKNEEALDTESSER 296

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +   A   +L IS+   +D G Y C+A N  G  T+ A+ ++T   Q + L   T   +I
Sbjct: 297  LVLLAGG-SLEISDVTEDDAGTYFCIADN--GNETIEAQAELTVQAQPEFLKQPT---NI 350

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
              +E     F+ ++T K  PT++W++ G ++  +  F+++ E N  VL      + D G 
Sbjct: 351  YAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVL---GLVKSDEGF 407

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A    G  +  A+L++
Sbjct: 408  YQCIAENDVGNAQAGAQLII 427



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 44/166 (26%), Positives = 80/166 (48%), Gaps = 10/166 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  +G P P + W  N+  +  + + ++++   G+  L I++VT  D+G   C+A N + 
Sbjct: 270 CVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTEDDAGTYFCIADNGNE 327

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
               Q  L V  +     P+F+++ + +   E   +V      G PTP + W K+G  +I
Sbjct: 328 TIEAQAELTVQAQ-----PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVI 382

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P+   +I  +     L + +   SD  +YQC A+N  G+    A+L
Sbjct: 383 PSDYFKIVKEHNLQVLGLVK---SDEGFYQCIAENDVGNAQAGAQL 425



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
           E    L   + P+  ++P N    E  D  F+ +++G P P V W KNG  +I S+  +I
Sbjct: 330 EAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKI 389

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           +  HN   L+V    KSD G Y  +AEN  G
Sbjct: 390 VKEHN---LQVLGLVKSDEGFYQCIAENDVG 417



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 52/189 (27%), Positives = 81/189 (42%), Gaps = 7/189 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+F    +   V  G     +C V     P V W  N + +  D   +++   SG   L+
Sbjct: 152 PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLD--DRVIKLPSG--MLV 207

Query: 452 ITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPK-FVERFSTLNVREGEPVV 509
           I+N T  D G+  CV  +    + + +  L V+   +V++   F+++ S L    G+ VV
Sbjct: 208 ISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVV 267

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L   A G PTP I W K+   +      R+    G S L+I      DA  Y C A N  
Sbjct: 268 LPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS-LEISDVTEDDAGTYFCIADNGN 326

Query: 570 GSTATRARL 578
            +   +A L
Sbjct: 327 ETIEAQAEL 335



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 13/141 (9%)

Query: 347 IVTSGYLAVESPTESYVQDQRSQY--ITDTQQRETEERIEISEKALAPQFVKVCQDRDVT 404
           ++  G L +   TE    D    Y  I D      E + E++ +A  P+F+K   +    
Sbjct: 299 LLAGGSLEISDVTE----DDAGTYFCIADNGNETIEAQAELTVQA-QPEFLKQPTNIYAH 353

Query: 405 EGKMTRFDCRVTGRPYPEVTWFIN-DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV 463
           E     F+C VTG+P P V W  N D  I  DY  KI V E   H L +  +  SD G  
Sbjct: 354 ESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDY-FKI-VKE---HNLQVLGLVKSDEGFY 408

Query: 464 TCVARNKSGETAFQCRLNVIE 484
            C+A N  G      +L ++E
Sbjct: 409 QCIAENDVGNAQAGAQLIILE 429



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 67/280 (23%), Positives = 120/280 (42%), Gaps = 34/280 (12%)

Query: 4545 VYWLKNGK--KVQPDIRNKILEEDGTYTLLILEAYPQ--DSGKYECVA-INSAGE--ARC 4597
            + W K+G    +  D R ++L +   +   ++ +     D G Y+CVA + S G   +R 
Sbjct: 84   IEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRT 143

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
                V  LP    +P+P +                + A   AI  +C++    +P V+W 
Sbjct: 144  AKLIVAGLPRFTSQPEPSS----------------VYAGNNAI-LNCEVNADLVPFVRWE 186

Query: 4658 KGDK-LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG-RVTVAAKLKVT-Q 4714
            +  + L+   +  ++        L IS A   D G Y+CV  +    + +   +LKV   
Sbjct: 187  QNRQPLLLDDRVIKLPSGM----LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPD 242

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGALIPETPDFQMIHEG 4773
            P+   +L  L     +V   GQ        +    PTI+W++ E AL  E+ +  ++  G
Sbjct: 243  PEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAG 302

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +  L I +  E+D GT+ C A      +E  A+L V+++
Sbjct: 303  GS--LEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ 340



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 5/113 (4%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + D    T + + ++TV   P+F +   NI   E  ++  EC +   G  T  V+W  NG
Sbjct: 321  IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNG 378

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
              +     F+   E +   L +L +   D G Y C A N +G A     L ++
Sbjct: 379  DMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIIL 428



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 45/159 (28%), Positives = 62/159 (38%), Gaps = 12/159 (7%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            + +G  +  I+W  N + ++     R V   G   LEI      D+GTY C A N  G  
Sbjct: 271  VASGLPTPTIKWMKNEEALDTESSERLVLLAGGS-LEISDVTEDDAGTYFCIADN--GNE 327

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
             I  + E   ++   +P F     NI    +     FEC V     P +K  W  NG  +
Sbjct: 328  TIEAQAELTVQA---QPEFLKQPTNIYA-HESMDIVFECEVTGKPTPTVK--WVKNGDMV 381

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              S   K V +    VL +      D G Y C A N  G
Sbjct: 382  IPSDYFKIVKEHNLQVLGLV---KSDEGFYQCIAENDVG 417



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 5/76 (6%)

Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG--VPIIPNPELRIHTDGGASTLDIP 551
           VE   TL+VR G  V+LN  A   P+P+I W+KDG  + ++ +   ++  DG     ++ 
Sbjct: 57  VEPVDTLSVR-GSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVV 115

Query: 552 RAKAS--DAAWYQCTA 565
            +K +  D  +YQC A
Sbjct: 116 HSKHNKPDEGYYQCVA 131



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            + G  +   + E  V   P+F+ Q  +    ES  + FEC V  K  P   ++W +NG +
Sbjct: 323  DNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTP--TVKWVKNGDM 380

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            +     ++ V +    +L +L +   D G Y C A ND G
Sbjct: 381  VIPSDYFKIVKEH---NLQVLGLVKSDEGFYQCIAENDVG 417



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 6/96 (6%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V  +P F+ +P +I    E   + FEC++       +K  W KNG  V     F+ + +
Sbjct: 336  TVQAQPEFLKQPTNIY-AHESMDIVFECEVTGKPTPTVK--WVKNGDMVIPSDYFKIVKE 392

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                 L ++ L+  D G Y C A N VG  +   +L
Sbjct: 393  HN---LQVLGLVKSDEGFYQCIAENDVGNAQAGAQL 425



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 5/100 (5%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
           V   P+F+    ++ A E   I FE  +   G PT  ++W+KNG  +  S  F  +    
Sbjct: 337 VQAQPEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFKIVKEH- 393

Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
             +L +L L   D G Y C A +  G A+  A L +   A
Sbjct: 394 --NLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHA 431



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            PEF   P+++   E+    FEC +      +  V+W  NG  ++     K + +    +L
Sbjct: 341  PEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVL 398

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
               G+ + D G Y C A N  G A    +L
Sbjct: 399  ---GLVKSDEGFYQCIAENDVGNAQAGAQL 425



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/112 (23%), Positives = 44/112 (39%), Gaps = 2/112 (1%)

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            E   +  P F+  P  +   E     F C VTG P P V W+ NG+ ++    +K+  + 
Sbjct: 334  ELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKE- 392

Query: 4164 MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
             ++  +    + D G  + I             L ++       G L +APR
Sbjct: 393  -HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPR 443



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 44/176 (25%), Positives = 76/176 (43%), Gaps = 17/176 (9%)

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK--PSKYFQMSRTADEYTLRI 4682
            ++EP+ D +   G ++  +C    +P P ++W K    +        Q+      +   +
Sbjct: 56   LVEPV-DTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNV 114

Query: 4683 --SEAFPEDEGDYKCVA-YNSAGR-VTVAAKLKVTQPDQADNLPALTPLRD-IVVYEGQP 4737
              S+    DEG Y+CVA   S G  ++  AKL V        LP  T   +   VY G  
Sbjct: 115  VHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVA------GLPRFTSQPEPSSVYAGNN 168

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            A    ++ + + P ++W  E    P   D ++I +  + +L+I N  E D G + C
Sbjct: 169  AILNCEVNADLVPFVRW--EQNRQPLLLDDRVI-KLPSGMLVISNATEGDGGLYRC 221



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)

Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            Q E   +++P F++  +N     E  +I  EC  E  G PT  V+W  NG  V     FK
Sbjct: 332  QAELTVQAQPEFLKQPTNIY-AHESMDIVFEC--EVTGKPTPTVKWVKNGDMVIPSDYFK 388

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT 1277
               +     L ++    +D G Y   A N +G+A   A + ++E +   T
Sbjct: 389  IVKEHN---LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATT 435



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/141 (23%), Positives = 57/141 (40%), Gaps = 10/141 (7%)

Query: 1796 TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTK 1855
            +S  L + +  SL++    E        + D+         E+ V   P F+ Q   PT 
Sbjct: 293  SSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQ---PTN 349

Query: 1856 L--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
            +   E     +EC +   P P   V+W  NG ++     ++   +     L +L +   D
Sbjct: 350  IYAHESMDIVFECEVTGKPTPT--VKWVKNGDMVIPSDYFKIVKEHN---LQVLGLVKSD 404

Query: 1914 SGEYTCKAINNLGQAVSSIRL 1934
             G Y C A N++G A +  +L
Sbjct: 405  EGFYQCIAENDVGNAQAGAQL 425



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 1/81 (1%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
           G D       SG P P + W KN + L   +   ++      +L + +  + D+G Y  +
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAG-GSLEISDVTEDDAGTYFCI 321

Query: 340 AENPNGCIVTSGYLAVESPTE 360
           A+N N  I     L V++  E
Sbjct: 322 ADNGNETIEAQAELTVQAQPE 342



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 5/88 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+    NI   E  +I FEC V     PT+K  W  N   +     +K   +    +L +
Sbjct: 343  FLKQPTNIYAHESMDIVFECEVTGKPTPTVK--WVKNGDMVIPSDYFKIVKEH---NLQV 397

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                + D G Y C A N  G+A     L
Sbjct: 398  LGLVKSDEGFYQCIAENDVGNAQAGAQL 425



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 5/65 (7%)

Query: 91  FEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARN 150
           FE ++ G PTP V W  K   +V  + Y     E    V  L+K     DEG Y C A N
Sbjct: 360 FECEVTGKPTPTVKWV-KNGDMVIPSDYFKIVKEHNLQVLGLVK----SDEGFYQCIAEN 414

Query: 151 QYGEA 155
             G A
Sbjct: 415 DVGNA 419



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 5/104 (4%)

Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNG 2017
            + D+       Q +  V  +P+F K   N    E   +  E  +T    PT  V+W  NG
Sbjct: 321  IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVT--GKPTPTVKWVKNG 378

Query: 2018 RPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEA 2061
              V     FK   +     L +L     D G Y C A N VG A
Sbjct: 379  DMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVGNA 419



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/106 (27%), Positives = 45/106 (42%), Gaps = 6/106 (5%)

Query: 1702 AQDEVITQA-PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            AQ E+  QA P F     +I   E+    FE  +   G P   V+W++NG  +  S+   
Sbjct: 331  AQAELTVQAQPEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFK 388

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             + +     L +      D G Y C A N++G A   + L +   A
Sbjct: 389  IVKEHNLQVLGLV---KSDEGFYQCIAENDVGNAQAGAQLIILEHA 431



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/113 (25%), Positives = 50/113 (44%), Gaps = 4/113 (3%)

Query: 1446 FVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALD 1505
            F+ +P  +  VI GQ V   C    +    +K  W KN + +      R +   G  +L+
Sbjct: 251  FLKQPSPLVRVI-GQDVVLPCVASGLPTPTIK--WMKNEEALDTESSERLVLLAGG-SLE 306

Query: 1506 IIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVL 1558
            I D+  +D+G Y C A N   T E    LT ++  + ++   N    E + ++
Sbjct: 307  ISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV 359



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 10/92 (10%)

Query: 2369 EPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI--EDSSRIT 2426
            E   + +P F +   NI    E     F+C +   G PT  V+W +N  ++   D  +I 
Sbjct: 334  ELTVQAQPEFLKQPTNI-YAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFKIV 390

Query: 2427 KTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            K H+   + +  S     DEG Y C A N +G
Sbjct: 391  KEHNLQVLGLVKS-----DEGFYQCIAENDVG 417



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)

Query: 2367 IPEPVTRQRPVFT-QPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI 2425
            +P+P      VF  QP   +  I  GQ     C  +  G PT  ++W +NE+ ++  S  
Sbjct: 240  LPDPEVISDLVFLKQPSPLVRVI--GQDVVLPC--VASGLPTPTIKWMKNEEALDTESSE 295

Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
                  G  S+ IS V ++D G Y C A N
Sbjct: 296  RLVLLAGG-SLEISDVTEDDAGTYFCIADN 324



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 1/65 (1%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G PT  I+W+KN ++++  S    +   G  SL++  +   D+G Y C A +     E +
Sbjct: 274 GLPTPTIKWMKNEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADNGNETIEAQ 332

Query: 724 AVLHV 728
           A L V
Sbjct: 333 AELTV 337



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  +  ++W  NG  +  S   + V       L++LG   +D G Y C A N  G A+ 
Sbjct: 365  TGKPTPTVKWVKNGDMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVGNAQA 421

Query: 3135 SVKL 3138
              +L
Sbjct: 422  GAQL 425


>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B protein.
          Length = 1960

 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 8/194 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP+  E L D     G+ ++ +C++ G P P + WYK  K ++   +  +    D     
Sbjct: 5    PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 64

Query: 4682 ISEAFPE-DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I ++    D G Y C A ++AG  +   K+ V  P +  N    +P       EG+ AQF
Sbjct: 65   ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPF-----VEGEDAQF 119

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRATTA 4798
               I     P I+W ++GAL+     FQ + E  +   VL+I    +ED G + C     
Sbjct: 120  TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 179

Query: 4799 AGQVETSAKLVVKS 4812
             G    SA+L ++S
Sbjct: 180  LGSARASAELRIQS 193



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIRNKILEE-DGTYT 4570
            PP F     +     G+ V+L  +VTGT KP+ + W K+GK VQ D  + ++E+ DG+  
Sbjct: 5    PPDFEEELADCTAELGETVKLACRVTGTPKPV-ISWYKDGKAVQVDPHHILIEDPDGSCA 63

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L++      DSG+Y C A ++AG      + +V +P                P  +  ++
Sbjct: 64   LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP----------------PRFVNKVR 107

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--MSRTADEYTLRISEAFPE 4688
                 EG+  +F+C I G P P ++WYK   L+     FQ      +    L I  A  E
Sbjct: 108  ASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKE 167

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            D G Y+C   N  G    +A+L++  P
Sbjct: 168  DLGLYECELVNRLGSARASAELRIQSP 194



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F +   D     G+  +  CRVTG P P ++W+ + + ++ D +H ++ +  G+ AL+
Sbjct: 6   PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 65

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           + ++T  DSG   C A + +G  +   ++ V      V P+FV +       EGE     
Sbjct: 66  LDSLTGVDSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFT 120

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVA 569
               G P P+I W KDG  +    + +  ++   G   L I  A   D   Y+C   N  
Sbjct: 121 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 180

Query: 570 GSTATRARL 578
           GS    A L
Sbjct: 181 GSARASAEL 189



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 42/143 (29%), Positives = 77/143 (53%), Gaps = 8/143 (5%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V   PRF+ ++   +   EG+ A + C IE  P P +R  WY +G +L +G++++T 
Sbjct: 93   KILVQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTL 149

Query: 1897 ND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
            ++   G   L I     ED G Y C+ +N LG A +S  L +QS    +  +Q +   E+
Sbjct: 150  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHREQ 206

Query: 1955 IQYLEDDSRYKRAVQDDSFVVEK 1977
            +    +D+  +RA Q+ + V+++
Sbjct: 207  LVAAVEDTTLERADQEVTSVLKR 229



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 13/201 (6%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQIHTFSTKSI 4467
            +PP F +++  C     E  +      G P P+I WY++   ++  P    I        
Sbjct: 4    RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 63

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI+  +   DS  +   A +  G       ++V+          VPP F    +      
Sbjct: 64   LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----------VPPRFVNKVRASPFVE 113

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLILEAYPQDSGKYE 4585
            G+  +    + G     + W K+G  +    + + L E   G   L+I  A  +D G YE
Sbjct: 114  GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 173

Query: 4586 CVAINSAGEARCDAECVVSLP 4606
            C  +N  G AR  AE  +  P
Sbjct: 174  CELVNRLGSARASAELRIQSP 194



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 7/136 (5%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
           PP+   K R S   EG DAQF   + G P P++ W+K+G  L   NK + ++        
Sbjct: 99  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 158

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP-TESYVQDQRSQYIT----DTQQR 377
           L +R   K D G Y     N  G    S  L ++SP  ++  Q  R Q +      T +R
Sbjct: 159 LVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLER 218

Query: 378 ETEERIEISEKALAPQ 393
             +E   + ++ L P+
Sbjct: 219 ADQEVTSVLKRLLGPK 234



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 57/233 (24%), Positives = 90/233 (38%), Gaps = 14/233 (6%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS-HRIRTVYAFG 3104
            RPP+F    +++ D +       + +   TG    VI W+ +GK ++   H I      G
Sbjct: 4    RPPDFE---EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG 60

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +      DSG Y C A +  G      K+          PRF   ++      +G
Sbjct: 61   SCALILDSLTGVDSGQYMCFAASAAGNCSTLGKI-----LVQVPPRFVNKVR-ASPFVEG 114

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEY 3222
            + A F CT+     P  +I WY +G  +    + +T+S+   G +VL I      D G Y
Sbjct: 115  EDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 172

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPS 3275
             C   N+ G     A +          E    + L    E  +L+ A Q+  S
Sbjct: 173  ECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTS 225



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 5/113 (4%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD- 3883
            +V  PP+F+ ++++    E E  +F C +E    P++R  WY++G LL +G++++T+ + 
Sbjct: 95   LVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 152

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              G + L I     ED G Y C  VN  G     A +  +  P +  Q Q  R
Sbjct: 153  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS-PMLQAQEQCHR 204



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP  +   ++ +   GG A+FE  + G+P P V+W +    LV+  + S +    T   S
Sbjct: 348 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTT--YS 405

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAIC 157
           L+++ +   D G YTC A+N  G+ +C
Sbjct: 406 LVLRHVASKDAGVYTCLAQNTGGQVLC 432



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 28/91 (30%), Positives = 48/91 (52%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP +     + + Q G  AQF+  + G+P+P VTW+K+  +L++S +          +L 
Sbjct: 348 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 407

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           +R+    D+G YT LA+N  G ++    L V
Sbjct: 408 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 438



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 5/115 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            VQ  P F   +++    VEG+       +E    P  +I W+K+G  LTTG + ++  + 
Sbjct: 96   VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEP 152

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
              GL+ L I +   +D G+Y C+  N LG A ++A ++I+       E  H + L
Sbjct: 153  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL 207



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 38/138 (27%), Positives = 66/138 (47%), Gaps = 10/138 (7%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD- 1498
            V + PRFV + ++    +EG+   F C +E      ++  W+K+G  +T G++F+ + + 
Sbjct: 96   VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 152

Query: 1499 -FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
              G + L I     ED G+Y C  VN +G+   S  L  +S    +   Q +   EQ+  
Sbjct: 153  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHREQLVA 209

Query: 1558 LEDRSKYHRTDMVDEVTT 1575
              + +   R D   EVT+
Sbjct: 210  AVEDTTLERAD--QEVTS 225



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 2/111 (1%)

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751
            E T +   + A D    + P   + ++D++      A FEA  I  GDP+  V W ++ V
Sbjct: 330  ETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKDSV 387

Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             +  S RL+   +    +L +++V  +D+G YTC A N  G+ +  + L V
Sbjct: 388  QLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 438



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 25/93 (26%), Positives = 47/93 (50%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++PP     ++  +      A+FE   +G+P P + WY+++  + +S         T   
Sbjct: 346  ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 405

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
            L++R V  +D+ V+  +A+N GG   C A L+V
Sbjct: 406  LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 438



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 26/91 (28%), Positives = 46/91 (50%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PPS  +T ++V   +G   + +  + G     V W K+  ++    R    +E  TY+L+
Sbjct: 348  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 407

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            +     +D+G Y C+A N+ G+  C AE +V
Sbjct: 408  LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 438



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 1/125 (0%)

Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
           T   + D  S  + +T QR    +   +  A  P      +D     G   +F+  + G 
Sbjct: 316 TGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGD 375

Query: 419 PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
           P P VTW+ +  Q+ D         E   ++L++ +V   D+GV TC+A+N  G+   + 
Sbjct: 376 PQPSVTWYKDSVQLVDS-TRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKA 434

Query: 479 RLNVI 483
            L V+
Sbjct: 435 ELLVL 439



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--H 4460
            G +    PP F  K++     E E A+F    +G P P I+WY++   +     FQ    
Sbjct: 92   GKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 151

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              S   +L+IR    ED  ++     NR G+A+ SA L ++    Q +
Sbjct: 152  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQ 199



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 5/95 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FGF 1234
            P FV  +   P V EG++    C +E  G P  ++ W+ +G  +T G++F+T  +   G 
Sbjct: 100  PRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 156

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            + L I  A+  D G Y    VN LGSA  SA +R+
Sbjct: 157  LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 191



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 36/134 (26%), Positives = 67/134 (50%), Gaps = 11/134 (8%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FG 3338
            PP+F+ +++  +  VEG+ A F   +     P ++  W+ +G  L  G++++T  +   G
Sbjct: 99   PPRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 155

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398
            +++L I    +E+ G YEC   N+LG     A L+  S    +L +Q     E   + + 
Sbjct: 156  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHRE---QLVA 209

Query: 3399 TLEDSMVRRKDTSV 3412
             +ED+ + R D  V
Sbjct: 210  AVEDTTLERADQEV 223



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND--FG 3751
            PPRF  +++ +  V EG    F C +E  G P  +I W+ +G    TG++  TL++   G
Sbjct: 99   PPRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 155

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + L I      D G Y C   N+ GSA  +A++
Sbjct: 156  LLVLVIRAASKEDLGLYECELVNRLGSARASAEL 189



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
           ++I+  T++ P     ++D+ + Q G  A FEA +    DP   V WYKD   +  S+R+
Sbjct: 339 QAIDTHTARPPSMQVTIEDV-QAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRL 395

Query: 820 TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           +        SL + H+ ++DAG YT  A N  G+ +  A + V
Sbjct: 396 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 438



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/95 (29%), Positives = 42/95 (44%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP +   ++D     G   +F   I G P P+V WYK    +  S      +    Y+L 
Sbjct: 348  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 407

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            +     +D G Y C+A N+ G+V   A+L V   D
Sbjct: 408  LRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGD 442



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            + + P  +  I+D +  + GG A FEA +E  GD    V W KD   +  S+R++     
Sbjct: 345  TARPPSMQVTIED-VQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEG 401

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
               +L ++ V   DAG YTC A N  GQ    A L ++
Sbjct: 402  TTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 439



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 9/130 (6%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND--FGF 3614
            PP F          E   A F C +       +R  W+ +G  L TG++ +T+++   G 
Sbjct: 99   PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 156

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
            ++L I    + D GLY C+  NR G A  S +L++   Q  +L+ Q   H +    +++ 
Sbjct: 157  LVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLVAAVE- 212

Query: 3675 LEETLHKREE 3684
             + TL + ++
Sbjct: 213  -DTTLERADQ 221



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 13/179 (7%)

Query: 1701 SAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            S   +++ Q P  F   ++     E + A F   +   G P  ++ W ++G  +   N+ 
Sbjct: 89   STLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKF 146

Query: 1760 TTMHD--FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESA 1817
             T+ +   G + L ++  + ED G Y C  +N LG A  S+ L +QS      E  H   
Sbjct: 147  QTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHRE- 205

Query: 1818 LQKIQQLEDSSRYQRREDVEVAVN-----QAPRFIT-QLNGPTKLSEGQSAHYECRIEP 1870
             Q +  +ED++  +  ++V   +      +AP   T  L GP     G  A  E   +P
Sbjct: 206  -QLVAAVEDTTLERADQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQP 263



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%)

Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448
            Q G TA F+   I  GDP   V W+++   + DS+R+++  +    S+ + HV  +D GV
Sbjct: 361  QTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGV 418

Query: 2449 YMCRASNLLGE 2459
            Y C A N  G+
Sbjct: 419  YTCLAQNTGGQ 429



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 8/127 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V   P+F   +     VEG +    C ++  G    ++ W+ +G  + TG++F+   E
Sbjct: 94   ILVQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSE 151

Query: 1365 --FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK-I 1421
                 + L + +   ED G+Y C+  N+LG A  S  LR+   +  +L++Q     E+ +
Sbjct: 152  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLV 208

Query: 1422 QYLEDTS 1428
              +EDT+
Sbjct: 209  AAVEDTT 215



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRL--QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF- 1365
            +AP F R L +   V G +V L C++  QP    T    W  +G P+++  R   +    
Sbjct: 1453 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQAT----WSKDGAPLESSSRVLISATLK 1508

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
            ++  L +L V  ED GVYTC  +N LG   T+  LR
Sbjct: 1509 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 1544



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 26/104 (25%), Positives = 39/104 (37%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P        +  + G      A   G P P +TW KD V ++ +  L    +G   +L +
Sbjct: 349 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVL 408

Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLH 594
               + DA  Y C AQN  G    +A L           +K+ H
Sbjct: 409 RHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQSH 452



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 6/107 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT-SIFNFGYV 828
            P F+R L D   +  G++     Q++  + P  +  W KDG P+ +SSR+  S     + 
Sbjct: 1455 PTFLRELSD-ETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 1511

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR--STVTADLG 873
             L I+ + AED G YT    N LG   +T  +R A R  S+   D+G
Sbjct: 1512 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIG 1558



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSG 3491
            EGE+A F   +     P ++  WY +G  L  G++F+T  +   G ++L I     ED G
Sbjct: 113  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 170

Query: 3492 EYLCRAYNNYGEAVTTASMKVQ 3513
             Y C   N  G A  +A +++Q
Sbjct: 171  LYECELVNRLGSARASAELRIQ 192



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746
            I+     PP   V I+D +    GG   F+  +E  GDP   + W+ +       +R+  
Sbjct: 341  IDTHTARPPSMQVTIED-VQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQ 397

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
              +    +L + ++ ++DAG YTC A N  G     A++
Sbjct: 398  QQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 436



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ +   PRF+  ++ +   VEG+ A F   +E        + WY +G  +T+ N+ QT 
Sbjct: 93   KILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAP--YPQIRWYKDGALLTTGNKFQTL 149

Query: 1096 HD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             +   G + L I +   ED G+Y     N  G A+ SA + +++         HR
Sbjct: 150  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 204



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP   V ++ V A  GG   FE  IE  GDP   + W K+   +  S+R +        S
Sbjct: 348 PPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 405

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           L +  +  +D+G YTC A +  G    KA L V
Sbjct: 406 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 438



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 22/84 (26%), Positives = 40/84 (47%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + D+    G  AQF+  I    +P++ W ++   + ++       EG    L++ +   +
Sbjct: 355  IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASK 414

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            D G +TC A    GQV   A+L+V
Sbjct: 415  DAGVYTCLAQNTGGQVLCKAELLV 438



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 5/96 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FG 2298
            PPRFV ++R +  V EG+ A F C +E    P +R  +Y +G  L +  +F    +   G
Sbjct: 99   PPRFVNKVRASPFV-EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 155

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             + L I+    ED G Y  + +N LG   ++  + +
Sbjct: 156  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 191



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/92 (28%), Positives = 43/92 (46%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F    + + F +G +A+F   + G P P + W +  A L   NK+      ++G + 
Sbjct: 99  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 158

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L+I+     D G Y C   N+ G A  S  ++
Sbjct: 159 LVIRAASKEDLGLYECELVNRLGSARASAELR 190



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSG 2180
            EG+ A F C +E    P+  I W+ +G  +  G++++T  +   G + L I     ED G
Sbjct: 113  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 170

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
             Y C+  N+LG A  +  L++
Sbjct: 171  LYECELVNRLGSARASAELRI 191



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            + ++  + G    FE  +E   DP   + W+ ++  L   TR     + +  SL + H  
Sbjct: 355  IEDVQAQTGGTAQFEAIIEG--DPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVA 412

Query: 2840 EEDSGIYTCKATNSKGSATTSGSLRCTGDKN 2870
             +D+G+YTC A N+ G       L   G  N
Sbjct: 413  SKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 443



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--R 690
           V  PP+F+  +++   +EG    F   IE  G P  +I W K+G  +   ++F ++   R
Sbjct: 96  VQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPR 153

Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQL 750
            G + L + + + +D G Y C  V+  G A   A L +       +   H E  Q +  +
Sbjct: 154 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHRE--QLVAAV 211

Query: 751 ED 752
           ED
Sbjct: 212 ED 213



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 1/107 (0%)

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
            K+ +  P  +  L D+ V  GQ++  +C++  +P     W K    ++ S    +S T  
Sbjct: 1449 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 1508

Query: 4677 EY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
             +  L I     ED G Y C   N+ G VT    L+  +   +   P
Sbjct: 1509 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCP 1555



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/56 (42%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 945  WLKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            W KDG P+E+SSR+        +  LTI  V   D G YTC   NA+G  TT+  L
Sbjct: 1488 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 1543



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-F 691
           V+ PP F   L   TA  G  +    R+   G P   I W K+G++++       I    
Sbjct: 2   VWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPD 59

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
           G  +L + SL   DSG+Y C A SA G   T  K ++ V PR
Sbjct: 60  GSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPR 101



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 4/92 (4%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF- 1899
            ++AP F+ +L+  T +  GQS    C++     P  +  W  +G  L+S  R   S    
Sbjct: 1452 DRAPTFLRELSDETVVL-GQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLK 1508

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             F  L IL V  ED G YTC   N LG   ++
Sbjct: 1509 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTT 1540



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            F+  L++     G ++   C V  S  P  +  W  +  PL S +R   +    ++  L 
Sbjct: 1457 FLRELSDETVVLGQSVTLACQV--SAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 1514

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            I     ED G+YTC  +N+ G+ TT+G LR
Sbjct: 1515 ILVVVAEDLGVYTCSVSNALGTVTTTGVLR 1544



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN--FGY 827
           P+F+  ++      EG +A F   +     P +R  WYKDG  +T  ++  ++     G 
Sbjct: 100 PRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 156

Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           + L I     ED G Y    VN+LG A ++A +R+
Sbjct: 157 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 191



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 8/101 (7%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTF-D 2696
            +AP F   L S + +V GQ V L  QV  +  P  +  W K+G  L + +R  + +T  +
Sbjct: 1453 RAPTFLREL-SDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKN 1509

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            F L+T+ +  +  +D G+YTC  +N LG   +T  ++  +R
Sbjct: 1510 FQLLTILV--VVAEDLGVYTCSVSNALGTVTTTGVLRKAER 1548



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAG 980
            EG  A F   +E  G    ++ W KDG  +   ++  T      G + L I++ +  D G
Sbjct: 113  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 170

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKIT 1040
             Y C   N +G A  SA L I +      E  H   L  +  +ED +   +R ++EV   
Sbjct: 171  LYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL--VAAVEDTT--LERADQEVTSV 226

Query: 1041 QKPRFLGP 1048
             K R LGP
Sbjct: 227  LK-RLLGP 233



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
            G +A FEA +E   D   +V WY +  Q+  + R+    +    +L +  V ++D+GVYT
Sbjct: 363  GGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 420

Query: 1118 VVARNAAGEAQLSASMTV 1135
             +A+N  G+    A + V
Sbjct: 421  CLAQNTGGQVLCKAELLV 438



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GY 1767
            +AP F   + D  V   Q+     ++     P  +  W ++G P+E+S+R+        +
Sbjct: 1453 RAPTFLRELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNF 1510

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
              L +  V  ED G YTC   N LG   T+  L
Sbjct: 1511 QLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 1543



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYV 2035
            P+F   ++ +   EG       T+     P +R  WY +G  +  G++F+T  +   G +
Sbjct: 100  PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLL 157

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
             L I  A  ED G Y C+  N +G A  ++ +++ +
Sbjct: 158  VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 193



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 2/101 (1%)

Query: 3551 EAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN 3610
            +  +  PP    T  D+      +A FE   I   D    V W+ +   L+  +R+    
Sbjct: 342  DTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRLSQQQ 399

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            +     L +  V  +DAG+YTC A N  G+     +L V G
Sbjct: 400  EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLG 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 9/129 (6%)

Query: 2621 LKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFK 2680
            ++E          +DT   + P     ++       G   + EA +E   DP   + W+K
Sbjct: 328  VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQF-EAIIEG--DPQPSVTWYK 384

Query: 2681 NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL 2740
            + V L    RL    +    +L +  + + D+G+YTC A N  G+ +  A + +      
Sbjct: 385  DSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV------ 438

Query: 2741 LGESLHPDS 2749
            LG    PDS
Sbjct: 439  LGGDNEPDS 447



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 8/91 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV---HTLNDFG 3751
            P F  E+ D   V  G  V   C+V     P  +  W  +G P  + SRV    TL +F 
Sbjct: 1455 PTFLRELSDET-VVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 1511

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
             + + +  + A D G YTC  +N  G+ TTT
Sbjct: 1512 LLTILV--VVAEDLGVYTCSVSNALGTVTTT 1540



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFV 3887
            PP F  ++   T E  E V+  CRV     PK  I WY++GK +     +  + D  G  
Sbjct: 5    PPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 62

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +L +  +   DSG+Y+C A +  G   T   I  +  P  +
Sbjct: 63   ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFV 103



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP FE+   +     G   K   ++ G P PV+SW  K    V+ + + +   +  G  +
Sbjct: 5   PPDFEEELADCTAELGETVKLACRVTGTPKPVISW-YKDGKAVQVDPHHILIEDPDGSCA 63

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L++  +   D G+Y C A +  G
Sbjct: 64  LILDSLTGVDSGQYMCFAASAAG 86



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EG++  F C +E +  P  +I W+ +   L +G ++++  +     + L I    +ED G
Sbjct: 113  EGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 170

Query: 2845 IYTCKATNSKGSATTSGSLR 2864
            +Y C+  N  GSA  S  LR
Sbjct: 171  LYECELVNRLGSARASAELR 190



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG+ A +   +     P +R  WY +G  L  G++F+T  +   G + L I +    D G
Sbjct: 113  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 170

Query: 2580 LYMCKAINRAG 2590
            LY C+ +NR G
Sbjct: 171  LYECELVNRLG 181



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 2/113 (1%)

Query: 1557 VLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            V E   + +    +D  T + P    ++++V+ + G  A FE   I   D    V WY +
Sbjct: 328  VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKD 385

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            +  L   +R ++       +L +     +D+G YTC A N  G+ +     +V
Sbjct: 386  SVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 438



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 4/108 (3%)

Query: 468  RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
            R K G  +F  RL+ + K    AP F+   S   V  G+ V L  +    P  + TW KD
Sbjct: 1435 RKKPGLASF--RLSGL-KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKD 1491

Query: 528  GVPIIPNPELRIH-TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            G P+  +  + I  T      L I    A D   Y C+  N  G+  T
Sbjct: 1492 GAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTT 1539



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYVA 2036
            P F + + +  V  G  V L   ++    P  +  W  +G P++   R   +     +  
Sbjct: 1455 PTFLRELSDETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQL 1512

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            L IL   AED G Y C  +NA+G   TT  ++
Sbjct: 1513 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 1544



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
            + +D    + P     I++++  + G +A FE  +    DP   + WY +   +  STR+
Sbjct: 339  QAIDTHTARPPSMQVTIEDVQA-QTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRL 395

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
                +     L + +  + D+G Y C A N  G+   +A +   G
Sbjct: 396  SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLG 440



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGF 3752
            PP F  E+ D      G  V   CRV   G P   I W+ +G+          + D  G 
Sbjct: 5    PPDFEEELAD-CTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGS 61

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             AL +D +   D+G+Y C A +  G+ +T  KI
Sbjct: 62   CALILDSLTGVDSGQYMCFAASAAGNCSTLGKI 94



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYV 1502
            P F+ R  S E V+ GQ V   C++        +  W K+G P+    R         + 
Sbjct: 1455 PTFL-RELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 1511

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGT 1527
             L I+ ++AED G+YTC   N +GT
Sbjct: 1512 LLTILVVVAEDLGVYTCSVSNALGT 1536



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP FV+   A    EGE A+F C + G P P++ W  +G  +  G++++
Sbjct: 99   PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 147



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/97 (28%), Positives = 40/97 (41%), Gaps = 3/97 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P F+ ++   TV   + V   C+V  +  P  +  W ++G  L S  R      +  F  
Sbjct: 1455 PTFLRELSDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKNFQL 1512

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L IL V AED G Y C   N  G   T   +   + P
Sbjct: 1513 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERP 1549



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 1613 WYHNNKPLKSGSRFTETNNF-GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666
            W  +  PL+S SR   +     F  L I+  + ED G YTC   NALG   T+G+
Sbjct: 1488 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGV 1542



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 2/104 (1%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            DT   +P  +     + Q   G     E  +E   DP   + WY +   L   +R     
Sbjct: 342  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 399

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            +    +L L  V  +D+G+YTC A N  G+    + +     DN
Sbjct: 400  EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 443



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            G++    CR+   P P   + WY +GK +Q   H     +  G  AL + ++ G DSG+Y
Sbjct: 20   GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 77

Query: 1918 TCKAINNLGQAVSSIRLNVQ 1937
             C A +  G   +  ++ VQ
Sbjct: 78   MCFAASAAGNCSTLGKILVQ 97



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR-FTSIFRFGYIS 695
            P F+  L   T + G  +    ++     P  +  W K+G  +E+SSR   S     +  
Sbjct: 1455 PTFLRELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQL 1512

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L +L +  +D G YTC   +A G   T  VL    R
Sbjct: 1513 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 1548



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 3/110 (2%)

Query: 3029 EDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG 3088
            E + R    Q  D  T RPP      +D V    G  A +EA  I  GD    + W+ + 
Sbjct: 330  ETTQRTYTYQAIDTHTARPPSMQVTIED-VQAQTGGTAQFEA--IIEGDPQPSVTWYKDS 386

Query: 3089 KTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
              +  S R+          L +    + D+G Y+C A N  GQ     +L
Sbjct: 387  VQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 436



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 3272 QTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRY 3331
            Q   T +A PP     I+DV +   G +A FEA  +   DP   V W+ +  +L    R 
Sbjct: 339  QAIDTHTARPPSMQVTIEDV-QAQTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRL 395

Query: 3332 RTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379
                +     L + +   +++G Y C+A N  G+   KA L     +N
Sbjct: 396  SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 443



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            D    +P   QV     +   G  A +EA +   GDP     WY + V+L   +R     
Sbjct: 342  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 399

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +    +L +  V + DAG+Y C A N  G
Sbjct: 400  EGTTYSLVLRHVASKDAGVYTCLAQNTGG 428



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 9/117 (7%)

Query: 2346 RPEGLEKI---RELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIP 2402
            RPEGLEK    R+      F+   +      + P F + L + + +  GQ+    C++  
Sbjct: 1424 RPEGLEKEGPPRKKPGLASFRLSGLKS--WDRAPTFLRELSD-ETVVLGQSVTLACQVS- 1479

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLG 2458
               P  +  W ++   +E SSR+  +     +  +TI  V  ED GVY C  SN LG
Sbjct: 1480 -AQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALG 1535



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP   ++  +   + G   +   +++G P+P ++W+K+G+ +     H +I   + +   
Sbjct: 5   PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 64

Query: 325 VRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESP 358
           + ++    DSG Y   A +  G   T G + V+ P
Sbjct: 65  ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 99



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFV 1235
            P F++ LS+   V  G+++ L C++     P  +  W  +G  +   SR         F 
Sbjct: 1455 PTFLRELSDETVVL-GQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 1511

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             L I+   + D G YT    N LG+  T+ ++R  ER
Sbjct: 1512 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 1548



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 2/88 (2%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTL 338
            G       Q+S  P  + TW K+G  L +S++  I  T  N   L +      D G YT 
Sbjct: 1469 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 1528

Query: 339  LAENPNGCIVTSGYL-AVESPTESYVQD 365
               N  G + T+G L   E P+ S   D
Sbjct: 1529 SVSNALGTVTTTGVLRKAERPSSSPCPD 1556



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP F       T E GE  +  CRVTG PKP + W  +G  +
Sbjct: 5    PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAV 46



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP     I+    +     +FE  +E   DP+  + WY++   L    R     +    S
Sbjct: 348  PPSMQVTIEDVQAQTGGTAQFEAIIEG--DPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 405

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            L + +V ++D+G Y C A N  G+   KA +
Sbjct: 406  LVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 436



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/82 (26%), Positives = 31/82 (37%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F++   D  V  G+     C+V+ +P  + TW  +   +       I         L
Sbjct: 1454 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 1513

Query: 451  MITNVTLSDSGVVTCVARNKSG 472
             I  V   D GV TC   N  G
Sbjct: 1514 TILVVVAEDLGVYTCSVSNALG 1535



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A +E  IE  P P+  V WY +   L    R     +    +L +  V  +D+G YT
Sbjct: 363  GGTAQFEAIIEGDPQPS--VTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 420

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            C A N  GQ +    L V   ++   DS+ +S   K+
Sbjct: 421  CLAQNTGGQVLCKAELLVLGGDN-EPDSEKQSHRRKL 456



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 4/95 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-GYV 2167
            P FL  L+  E +  G      C+V     P     W  +G  + +  R   +     + 
Sbjct: 1455 PTFLRELSD-ETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQ 1511

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
             L IL   AED G Y C  +N LG    T  L+ A
Sbjct: 1512 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKA 1546



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFGYVA 2036
            P F + + +     G  V L   +T    P   + WY +G+ VQ   H        G  A
Sbjct: 6    PDFEEELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCA 63

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +      D+G YMC A +A G   T   + V
Sbjct: 64   LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 96



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 2/100 (2%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            D    + P     + +++   G     E  ++  GD    V W+ +   +    R     
Sbjct: 342  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 399

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            E    +L L  V  +D+GVYTC A N  G+ +    L V+
Sbjct: 400  EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 439



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 3/107 (2%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            +++    + P   V + +++  + G  A FEA +    DP   V WY +   L   +R  
Sbjct: 340  AIDTHTARPPSMQVTIEDVQ-AQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLS 396

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
               +     L +     +D+G Y C A N  G+ +  A + V G  N
Sbjct: 397  QQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 443



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 11/159 (6%)

Query: 3936 GMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRF---VTQIQSQTSLVEMETTK 3992
            G    E L  + + + + T++   T   + D    +PP     +  +Q+QT      T +
Sbjct: 313  GAGTGELLWDVHSHVVRETTQRTYTYQAI-DTHTARPPSMQVTIEDVQAQTG----GTAQ 367

Query: 3993 FECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATN 4052
            FE  +   GDP   V W+ +   L+   R +   +    ++    V  +D+G Y C A N
Sbjct: 368  FEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQN 425

Query: 4053 LYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
              G    KA +   G      DS+   H + +    E++
Sbjct: 426  TGGQVLCKAELLVLGGDN-EPDSEKQSHRRKLHSFYEVK 463



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2919 AEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVY 2977
            ++  +V GQ + L  QV  +  P  +  W  +G  LE  SR  +++    F  L ++ V 
Sbjct: 1462 SDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVV 1519

Query: 2978 ERDSGIYTCKAYNKRGEAFTSSTV 3001
              D G+YTC   N  G   T+  +
Sbjct: 1520 AEDLGVYTCSVSNALGTVTTTGVL 1543



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P   PP F  EL   T    G+T    C+V     P   I +Y +GKA+Q      +  D
Sbjct: 1    PVWRPPDFEEELADCTAEL-GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIED 57

Query: 2297 -FGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              G  +L +      D+G+Y   A +A G+C++
Sbjct: 58   PDGSCALILDSLTGVDSGQYMCFAASAAGNCST 90



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A FE  +E   DP  ++ W+ +  ++    R     +    +L + +  ++D+G Y 
Sbjct: 363  GGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 420

Query: 2184 CKATNKLGEAVNTCTLKVAGHRN 2206
            C A N  G+ +    L V G  N
Sbjct: 421  CLAQNTGGQVLCKAELLVLGGDN 443



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 3/122 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P F    SD  +    S    C++      + +  W  +G PL + SRV        F +
Sbjct: 1455 PTFLRELSDETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQL 1512

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V   D G+YTC  +N  G  T +  L+   R      P +   +  G   + K  
Sbjct: 1513 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPV 1572

Query: 3677 ET 3678
            E+
Sbjct: 1573 ES 1574



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 4/88 (4%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF-GYV 2300
            P F+ EL   T V  G++    CQV     P  +  +  +G  L+S++R  I+     + 
Sbjct: 1455 PTFLRELSDETVVL-GQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQ 1511

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTS 2328
             L I   V ED G Y+    NALG  T+
Sbjct: 1512 LLTILVVVAEDLGVYTCSVSNALGTVTT 1539



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 943  VEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+ V+     I      G  AL + S+T  D+G Y C A +A G  +T   + +
Sbjct: 37   ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 96


>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
            calmodulin and titin-interacting RhoGEF protein.
          Length = 2582

 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 8/194 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP+  E L D     G+ ++ +C++ G P P + WYK  K ++   +  +    D     
Sbjct: 629  PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688

Query: 4682 ISEAFPE-DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I ++    D G Y C A ++AG  +   K+ V  P +  N    +P       EG+ AQF
Sbjct: 689  ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPF-----VEGEDAQF 743

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRATTA 4798
               I     P I+W ++GAL+     FQ + E  +   VL+I    +ED G + C     
Sbjct: 744  TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 803

Query: 4799 AGQVETSAKLVVKS 4812
             G    SA+L ++S
Sbjct: 804  LGSARASAELRIQS 817



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIRNKILEE-DGTYT 4570
            PP F     +     G+ V+L  +VTGT KP+ + W K+GK VQ D  + ++E+ DG+  
Sbjct: 629  PPDFEEELADCTAELGETVKLACRVTGTPKPV-ISWYKDGKAVQVDPHHILIEDPDGSCA 687

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L++      DSG+Y C A ++AG      + +V +P                P  +  ++
Sbjct: 688  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP----------------PRFVNKVR 731

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--MSRTADEYTLRISEAFPE 4688
                 EG+  +F+C I G P P ++WYK   L+     FQ      +    L I  A  E
Sbjct: 732  ASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKE 791

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            D G Y+C   N  G    +A+L++  P
Sbjct: 792  DLGLYECELVNRLGSARASAELRIQSP 818



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F +   D     G+  +  CRVTG P P ++W+ + + ++ D +H ++ +  G+ AL+
Sbjct: 630 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 689

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           + ++T  DSG   C A + +G  +   ++ V      V P+FV +       EGE     
Sbjct: 690 LDSLTGVDSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFT 744

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVA 569
               G P P+I W KDG  +    + +  ++   G   L I  A   D   Y+C   N  
Sbjct: 745 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 804

Query: 570 GSTATRARL 578
           GS    A L
Sbjct: 805 GSARASAEL 813



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 42/143 (29%), Positives = 77/143 (53%), Gaps = 8/143 (5%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V   PRF+ ++   +   EG+ A + C IE  P P +R  WY +G +L +G++++T 
Sbjct: 717  KILVQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTL 773

Query: 1897 ND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
            ++   G   L I     ED G Y C+ +N LG A +S  L +QS    +  +Q +   E+
Sbjct: 774  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHREQ 830

Query: 1955 IQYLEDDSRYKRAVQDDSFVVEK 1977
            +    +D+  +RA Q+ + V+++
Sbjct: 831  LVAAVEDTTLERADQEVTSVLKR 853



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 13/201 (6%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQIHTFSTKSI 4467
            +PP F +++  C     E  +      G P P+I WY++   ++  P    I        
Sbjct: 628  RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI+  +   DS  +   A +  G       ++V+          VPP F    +      
Sbjct: 688  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----------VPPRFVNKVRASPFVE 737

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLILEAYPQDSGKYE 4585
            G+  +    + G     + W K+G  +    + + L E   G   L+I  A  +D G YE
Sbjct: 738  GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 797

Query: 4586 CVAINSAGEARCDAECVVSLP 4606
            C  +N  G AR  AE  +  P
Sbjct: 798  CELVNRLGSARASAELRIQSP 818



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 7/136 (5%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
           PP+   K R S   EG DAQF   + G P P++ W+K+G  L   NK + ++        
Sbjct: 723 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 782

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP-TESYVQDQRSQYIT----DTQQR 377
           L +R   K D G Y     N  G    S  L ++SP  ++  Q  R Q +      T +R
Sbjct: 783 LVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLER 842

Query: 378 ETEERIEISEKALAPQ 393
             +E   + ++ L P+
Sbjct: 843 ADQEVTSVLKRLLGPK 858



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 57/233 (24%), Positives = 90/233 (38%), Gaps = 14/233 (6%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS-HRIRTVYAFG 3104
            RPP+F    +++ D +       + +   TG    VI W+ +GK ++   H I      G
Sbjct: 628  RPPDFE---EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG 684

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +      DSG Y C A +  G      K+          PRF   ++      +G
Sbjct: 685  SCALILDSLTGVDSGQYMCFAASAAGNCSTLGKI-----LVQVPPRFVNKVR-ASPFVEG 738

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEY 3222
            + A F CT+     P  +I WY +G  +    + +T+S+   G +VL I      D G Y
Sbjct: 739  EDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 796

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPS 3275
             C   N+ G     A +          E    + L    E  +L+ A Q+  S
Sbjct: 797  ECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTS 849



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 5/113 (4%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD- 3883
            +V  PP+F+ ++++    E E  +F C +E    P++R  WY++G LL +G++++T+ + 
Sbjct: 719  LVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 776

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              G + L I     ED G Y C  VN  G     A +  +  P +  Q Q  R
Sbjct: 777  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS-PMLQAQEQCHR 828



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  +   ++ +   GG A+FE  + G+P P V+W +    LV+  + S +    T   S
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTT--YS 1029

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAIC 157
            L+++ +   D G YTC A+N  G+ +C
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLC 1056



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 28/91 (30%), Positives = 48/91 (52%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP +     + + Q G  AQF+  + G+P+P VTW+K+  +L++S +          +L 
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            +R+    D+G YT LA+N  G ++    L V
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 5/115 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            VQ  P F   +++    VEG+       +E    P  +I W+K+G  LTTG + ++  + 
Sbjct: 720  VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEP 776

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
              GL+ L I +   +D G+Y C+  N LG A ++A ++I+       E  H + L
Sbjct: 777  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL 831



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 38/138 (27%), Positives = 66/138 (47%), Gaps = 10/138 (7%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD- 1498
            V + PRFV + ++    +EG+   F C +E      ++  W+K+G  +T G++F+ + + 
Sbjct: 720  VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 776

Query: 1499 -FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
              G + L I     ED G+Y C  VN +G+   S  L  +S    +   Q +   EQ+  
Sbjct: 777  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHREQLVA 833

Query: 1558 LEDRSKYHRTDMVDEVTT 1575
              + +   R D   EVT+
Sbjct: 834  AVEDTTLERAD--QEVTS 849



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 2/111 (1%)

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751
            E T +   + A D    + P   + ++D++      A FEA  I  GDP+  V W ++ V
Sbjct: 954  ETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKDSV 1011

Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             +  S RL+   +    +L +++V  +D+G YTC A N  G+ +  + L V
Sbjct: 1012 QLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 25/93 (26%), Positives = 47/93 (50%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++PP     ++  +      A+FE   +G+P P + WY+++  + +S         T   
Sbjct: 970  ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 1029

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
            L++R V  +D+ V+  +A+N GG   C A L+V
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 26/91 (28%), Positives = 46/91 (50%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PPS  +T ++V   +G   + +  + G     V W K+  ++    R    +E  TY+L+
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            +     +D+G Y C+A N+ G+  C AE +V
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 1/125 (0%)

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
            T   + D  S  + +T QR    +   +  A  P      +D     G   +F+  + G 
Sbjct: 940  TGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGD 999

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
            P P VTW+ +  Q+ D         E   ++L++ +V   D+GV TC+A+N  G+   + 
Sbjct: 1000 PQPSVTWYKDSVQLVDS-TRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKA 1058

Query: 479  RLNVI 483
             L V+
Sbjct: 1059 ELLVL 1063



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--H 4460
            G +    PP F  K++     E E A+F    +G P P I+WY++   +     FQ    
Sbjct: 716  GKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 775

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              S   +L+IR    ED  ++     NR G+A+ SA L ++    Q +
Sbjct: 776  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQ 823



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 5/95 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FGF 1234
            P FV  +   P V EG++    C +E  G P  ++ W+ +G  +T G++F+T  +   G 
Sbjct: 724  PRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 780

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            + L I  A+  D G Y    VN LGSA  SA +R+
Sbjct: 781  LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 36/134 (26%), Positives = 67/134 (50%), Gaps = 11/134 (8%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FG 3338
            PP+F+ +++  +  VEG+ A F   +     P ++  W+ +G  L  G++++T  +   G
Sbjct: 723  PPRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 779

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398
            +++L I    +E+ G YEC   N+LG     A L+  S    +L +Q     E   + + 
Sbjct: 780  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHRE---QLVA 833

Query: 3399 TLEDSMVRRKDTSV 3412
             +ED+ + R D  V
Sbjct: 834  AVEDTTLERADQEV 847



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND--FG 3751
            PPRF  +++ +  V EG    F C +E  G P  +I W+ +G    TG++  TL++   G
Sbjct: 723  PPRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 779

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + L I      D G Y C   N+ GSA  +A++
Sbjct: 780  LLVLVIRAASKEDLGLYECELVNRLGSARASAEL 813



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            ++I+  T++ P     ++D+ + Q G  A FEA +    DP   V WYKD   +  S+R+
Sbjct: 963  QAIDTHTARPPSMQVTIEDV-QAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRL 1019

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +        SL + H+ ++DAG YT  A N  G+ +  A + V
Sbjct: 1020 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/95 (29%), Positives = 42/95 (44%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP +   ++D     G   +F   I G P P+V WYK    +  S      +    Y+L 
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            +     +D G Y C+A N+ G+V   A+L V   D
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGD 1066



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            + + P  +  I+D +  + GG A FEA +E  GD    V W KD   +  S+R++     
Sbjct: 969  TARPPSMQVTIED-VQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEG 1025

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
               +L ++ V   DAG YTC A N  GQ    A L ++
Sbjct: 1026 TTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 9/130 (6%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND--FGF 3614
            PP F          E   A F C +       +R  W+ +G  L TG++ +T+++   G 
Sbjct: 723  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 780

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
            ++L I    + D GLY C+  NR G A  S +L++   Q  +L+ Q   H +    +++ 
Sbjct: 781  LVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLVAAVE- 836

Query: 3675 LEETLHKREE 3684
             + TL + ++
Sbjct: 837  -DTTLERADQ 845



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 13/179 (7%)

Query: 1701 SAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            S   +++ Q P  F   ++     E + A F   +   G P  ++ W ++G  +   N+ 
Sbjct: 713  STLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKF 770

Query: 1760 TTMHD--FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESA 1817
             T+ +   G + L ++  + ED G Y C  +N LG A  S+ L +QS      E  H   
Sbjct: 771  QTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHRE- 829

Query: 1818 LQKIQQLEDSSRYQRREDVEVAVN-----QAPRFIT-QLNGPTKLSEGQSAHYECRIEP 1870
             Q +  +ED++  +  ++V   +      +AP   T  L GP     G  A  E   +P
Sbjct: 830  -QLVAAVEDTTLERADQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQP 887



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%)

Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448
            Q G TA F+   I  GDP   V W+++   + DS+R+++  +    S+ + HV  +D GV
Sbjct: 985  QTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGV 1042

Query: 2449 YMCRASNLLGE 2459
            Y C A N  G+
Sbjct: 1043 YTCLAQNTGGQ 1053



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 8/127 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V   P+F   +     VEG +    C ++  G    ++ W+ +G  + TG++F+   E
Sbjct: 718  ILVQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSE 775

Query: 1365 --FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK-I 1421
                 + L + +   ED G+Y C+  N+LG A  S  LR+   +  +L++Q     E+ +
Sbjct: 776  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLV 832

Query: 1422 QYLEDTS 1428
              +EDT+
Sbjct: 833  AAVEDTT 839



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRL--QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF- 1365
            +AP F R L +   V G +V L C++  QP    T    W  +G P+++  R   +    
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQAT----WSKDGAPLESSSRVLISATLK 2132

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
            ++  L +L V  ED GVYTC  +N LG   T+  LR
Sbjct: 2133 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 26/104 (25%), Positives = 39/104 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P        +  + G      A   G P P +TW KD V ++ +  L    +G   +L +
Sbjct: 973  PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVL 1032

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLH 594
                + DA  Y C AQN  G    +A L           +K+ H
Sbjct: 1033 RHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQSH 1076



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 6/107 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT-SIFNFGYV 828
            P F+R L D   +  G++     Q++  + P  +  W KDG P+ +SSR+  S     + 
Sbjct: 2079 PTFLRELSD-ETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR--STVTADLG 873
             L I+ + AED G YT    N LG   +T  +R A R  S+   D+G
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIG 2182



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSG 3491
            EGE+A F   +     P ++  WY +G  L  G++F+T  +   G ++L I     ED G
Sbjct: 737  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 3492 EYLCRAYNNYGEAVTTASMKVQ 3513
             Y C   N  G A  +A +++Q
Sbjct: 795  LYECELVNRLGSARASAELRIQ 816



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746
            I+     PP   V I+D +    GG   F+  +E  GDP   + W+ +       +R+  
Sbjct: 965  IDTHTARPPSMQVTIED-VQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQ 1021

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
              +    +L + ++ ++DAG YTC A N  G     A++
Sbjct: 1022 QQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ +   PRF+  ++ +   VEG+ A F   +E        + WY +G  +T+ N+ QT 
Sbjct: 717  KILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAP--YPQIRWYKDGALLTTGNKFQTL 773

Query: 1096 HD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             +   G + L I +   ED G+Y     N  G A+ SA + +++         HR
Sbjct: 774  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 828



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP   V ++ V A  GG   FE  IE  GDP   + W K+   +  S+R +        S
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 1029

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +  +  +D+G YTC A +  G    KA L V
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 22/84 (26%), Positives = 40/84 (47%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + D+    G  AQF+  I    +P++ W ++   + ++       EG    L++ +   +
Sbjct: 979  IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASK 1038

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            D G +TC A    GQV   A+L+V
Sbjct: 1039 DAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 5/96 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FG 2298
            PPRFV ++R +  V EG+ A F C +E    P +R  +Y +G  L +  +F    +   G
Sbjct: 723  PPRFVNKVRASPFV-EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 779

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             + L I+    ED G Y  + +N LG   ++  + +
Sbjct: 780  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/92 (28%), Positives = 43/92 (46%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F    + + F +G +A+F   + G P P + W +  A L   NK+      ++G + 
Sbjct: 723 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 782

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L+I+     D G Y C   N+ G A  S  ++
Sbjct: 783 LVIRAASKEDLGLYECELVNRLGSARASAELR 814



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSG 2180
            EG+ A F C +E    P+  I W+ +G  +  G++++T  +   G + L I     ED G
Sbjct: 737  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
             Y C+  N+LG A  +  L++
Sbjct: 795  LYECELVNRLGSARASAELRI 815



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            + ++  + G    FE  +E   DP   + W+ ++  L   TR     + +  SL + H  
Sbjct: 979  IEDVQAQTGGTAQFEAIIEG--DPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVA 1036

Query: 2840 EEDSGIYTCKATNSKGSATTSGSLRCTGDKN 2870
             +D+G+YTC A N+ G       L   G  N
Sbjct: 1037 SKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/81 (30%), Positives = 47/81 (58%), Gaps = 6/81 (7%)

Query: 4639 AIEFSCKIVGKPLPTVQWYK-----GDKLIKP-SKYFQMSRTADEYTLRISEAFPEDEGD 4692
            +I FS K+ G+P+PTV W +     G   I P +  + ++ +A +++L + +   + +G 
Sbjct: 2    SITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGT 61

Query: 4693 YKCVAYNSAGRVTVAAKLKVT 4713
            Y C+A N+AG+   +A L V+
Sbjct: 62   YTCIASNAAGQALCSASLHVS 82



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--R 690
           V  PP+F+  +++   +EG    F   IE  G P  +I W K+G  +   ++F ++   R
Sbjct: 720 VQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPR 777

Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQL 750
            G + L + + + +D G Y C  V+  G A   A L +       +   H E  Q +  +
Sbjct: 778 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHRE--QLVAAV 835

Query: 751 ED 752
           ED
Sbjct: 836 ED 837



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 1/107 (0%)

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
            K+ +  P  +  L D+ V  GQ++  +C++  +P     W K    ++ S    +S T  
Sbjct: 2073 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 2132

Query: 4677 EY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
             +  L I     ED G Y C   N+ G VT    L+  +   +   P
Sbjct: 2133 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCP 2179



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/56 (42%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 945  WLKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            W KDG P+E+SSR+        +  LTI  V   D G YTC   NA+G  TT+  L
Sbjct: 2112 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 2167



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-F 691
           V+ PP F   L   TA  G  +    R+   G P   I W K+G++++       I    
Sbjct: 626 VWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPD 683

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
           G  +L + SL   DSG+Y C A SA G   T  K ++ V PR
Sbjct: 684 GSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPR 725



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 4/92 (4%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF- 1899
            ++AP F+ +L+  T +  GQS    C++     P  +  W  +G  L+S  R   S    
Sbjct: 2076 DRAPTFLRELSDETVVL-GQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLK 2132

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             F  L IL V  ED G YTC   N LG   ++
Sbjct: 2133 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTT 2164



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            F+  L++     G ++   C V  S  P  +  W  +  PL S +R   +    ++  L 
Sbjct: 2081 FLRELSDETVVLGQSVTLACQV--SAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 2138

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            I     ED G+YTC  +N+ G+ TT+G LR
Sbjct: 2139 ILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN--FGY 827
           P+F+  ++      EG +A F   +     P +R  WYKDG  +T  ++  ++     G 
Sbjct: 724 PRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 780

Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           + L I     ED G Y    VN+LG A ++A +R+
Sbjct: 781 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 8/101 (7%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTF-D 2696
            +AP F   L S + +V GQ V L  QV  +  P  +  W K+G  L + +R  + +T  +
Sbjct: 2077 RAPTFLREL-SDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKN 2133

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            F L+T+ +  +  +D G+YTC  +N LG   +T  ++  +R
Sbjct: 2134 FQLLTILV--VVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAG 980
            EG  A F   +E  G    ++ W KDG  +   ++  T      G + L I++ +  D G
Sbjct: 737  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKIT 1040
             Y C   N +G A  SA L I +      E  H   L  +  +ED +   +R ++EV   
Sbjct: 795  LYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL--VAAVEDTT--LERADQEVTSV 850

Query: 1041 QKPRFLGP 1048
             K R LGP
Sbjct: 851  LK-RLLGP 857



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
            G +A FEA +E   D   +V WY +  Q+  + R+    +    +L +  V ++D+GVYT
Sbjct: 987  GGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 1044

Query: 1118 VVARNAAGEAQLSASMTV 1135
             +A+N  G+    A + V
Sbjct: 1045 CLAQNTGGQVLCKAELLV 1062



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 6/77 (7%)

Query: 4740 FKTQITSKIKPTIQWLREGA------LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            F  ++  +  PT+ WLRE A      + P+TP + +        L++ +   +  GT+TC
Sbjct: 5    FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 64

Query: 4794 RATTAAGQVETSAKLVV 4810
             A+ AAGQ   SA L V
Sbjct: 65   IASNAAGQALCSASLHV 81



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GY 1767
            +AP F   + D  V   Q+     ++     P  +  W ++G P+E+S+R+        +
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNF 2134

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
              L +  V  ED G YTC   N LG   T+  L
Sbjct: 2135 QLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 2167



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYV 2035
            P+F   ++ +   EG       T+     P +R  WY +G  +  G++F+T  +   G +
Sbjct: 724  PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLL 781

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
             L I  A  ED G Y C+  N +G A  ++ +++ +
Sbjct: 782  VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 817



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 2/101 (1%)

Query: 3551 EAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN 3610
            +  +  PP    T  D+      +A FE   I   D    V W+ +   L+  +R+    
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            +     L +  V  +DAG+YTC A N  G+     +L V G
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLG 1064



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 9/129 (6%)

Query: 2621 LKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFK 2680
            ++E          +DT   + P     ++       G   + EA +E   DP   + W+K
Sbjct: 952  VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQF-EAIIEG--DPQPSVTWYK 1008

Query: 2681 NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL 2740
            + V L    RL    +    +L +  + + D+G+YTC A N  G+ +  A + +      
Sbjct: 1009 DSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV------ 1062

Query: 2741 LGESLHPDS 2749
            LG    PDS
Sbjct: 1063 LGGDNEPDS 1071



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 8/91 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV---HTLNDFG 3751
            P F  E+ D   V  G  V   C+V     P  +  W  +G P  + SRV    TL +F 
Sbjct: 2079 PTFLRELSDET-VVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
             + + +  + A D G YTC  +N  G+ TTT
Sbjct: 2136 LLTILV--VVAEDLGVYTCSVSNALGTVTTT 2164



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFV 3887
            PP F  ++   T E  E V+  CRV     PK  I WY++GK +     +  + D  G  
Sbjct: 629  PPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 686

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +L +  +   DSG+Y+C A +  G   T   I  +  P  +
Sbjct: 687  ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFV 727



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP FE+   +     G   K   ++ G P PV+SW  K    V+ + + +   +  G  +
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISW-YKDGKAVQVDPHHILIEDPDGSCA 687

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L++  +   D G+Y C A +  G
Sbjct: 688 LILDSLTGVDSGQYMCFAASAAG 710



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EG++  F C +E +  P  +I W+ +   L +G ++++  +     + L I    +ED G
Sbjct: 737  EGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 2845 IYTCKATNSKGSATTSGSLR 2864
            +Y C+  N  GSA  S  LR
Sbjct: 795  LYECELVNRLGSARASAELR 814



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG+ A +   +     P +R  WY +G  L  G++F+T  +   G + L I +    D G
Sbjct: 737  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 2580 LYMCKAINRAG 2590
            LY C+ +NR G
Sbjct: 795  LYECELVNRLG 805



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 91  FEGKLRGNPTPVVSWTRKKAPL------VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           F  K+ G P P V W R++A         +   Y++  + Q    SL++  +G   +G Y
Sbjct: 5   FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH--SLVLLDVGRQHQGTY 62

Query: 145 TCTARNQYGEAICSVYIQPEG 165
           TC A N  G+A+CS  +   G
Sbjct: 63  TCIASNAAGQALCSASLHVSG 83



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 2/113 (1%)

Query: 1557 VLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            V E   + +    +D  T + P    ++++V+ + G  A FE   I   D    V WY +
Sbjct: 952  VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKD 1009

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            +  L   +R ++       +L +     +D+G YTC A N  G+ +     +V
Sbjct: 1010 SVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 4/108 (3%)

Query: 468  RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
            R K G  +F  RL+ + K    AP F+   S   V  G+ V L  +    P  + TW KD
Sbjct: 2059 RKKPGLASF--RLSGL-KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKD 2115

Query: 528  GVPIIPNPELRIH-TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            G P+  +  + I  T      L I    A D   Y C+  N  G+  T
Sbjct: 2116 GAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTT 2163



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYVA 2036
            P F + + +  V  G  V L   ++    P  +  W  +G P++   R   +     +  
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            L IL   AED G Y C  +NA+G   TT  ++
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
            + +D    + P     I++++  + G +A FE  +    DP   + WY +   +  STR+
Sbjct: 963  QAIDTHTARPPSMQVTIEDVQA-QTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRL 1019

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
                +     L + +  + D+G Y C A N  G+   +A +   G
Sbjct: 1020 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLG 1064



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGF 3752
            PP F  E+ D      G  V   CRV   G P   I W+ +G+          + D  G 
Sbjct: 629  PPDFEEELAD-CTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGS 685

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             AL +D +   D+G+Y C A +  G+ +T  KI
Sbjct: 686  CALILDSLTGVDSGQYMCFAASAAGNCSTLGKI 718



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYV 1502
            P F+ R  S E V+ GQ V   C++        +  W K+G P+    R         + 
Sbjct: 2079 PTFL-RELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGT 1527
             L I+ ++AED G+YTC   N +GT
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGT 2160



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP FV+   A    EGE A+F C + G P P++ W  +G  +  G++++
Sbjct: 723  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 771



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/97 (28%), Positives = 40/97 (41%), Gaps = 3/97 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P F+ ++   TV   + V   C+V  +  P  +  W ++G  L S  R      +  F  
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L IL V AED G Y C   N  G   T   +   + P
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERP 2173



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 1613 WYHNNKPLKSGSRFTETNNF-GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666
            W  +  PL+S SR   +     F  L I+  + ED G YTC   NALG   T+G+
Sbjct: 2112 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGV 2166



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 7/90 (7%)

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKK-----VQPDIRNKILEEDGT-YTLLILEAYPQDSGKY 4584
            +    KV G     V+WL+   +     + PD     +      ++L++L+   Q  G Y
Sbjct: 3    ITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTY 62

Query: 4585 ECVAINSAGEARCDAECVVS-LPATKDKPK 4613
             C+A N+AG+A C A   VS LP  +++ K
Sbjct: 63   TCIASNAAGQALCSASLHVSGLPKVEEQEK 92



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            Q  +A+ K   +++    Q+R  + + V + P F  +L   T    G++    CR+   P
Sbjct: 601  QARTAIIKSSWVKEICGIQQR--LALPVWRPPDFEEELADCTA-ELGETVKLACRVTGTP 657

Query: 1873 DPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             P   + WY +GK +Q   H     +  G  AL + ++ G DSG+Y C A +  G   + 
Sbjct: 658  KPV--ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTL 715

Query: 1932 IRLNVQ 1937
             ++ VQ
Sbjct: 716  GKILVQ 721



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 2/104 (1%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            DT   +P  +     + Q   G     E  +E   DP   + WY +   L   +R     
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            +    +L L  V  +D+G+YTC A N  G+    + +     DN
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR-FTSIFRFGYIS 695
            P F+  L   T + G  +    ++     P  +  W K+G  +E+SSR   S     +  
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L +L +  +D G YTC   +A G   T  VL    R
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 3/110 (2%)

Query: 3029 EDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG 3088
            E + R    Q  D  T RPP      +D V    G  A +EA  I  GD    + W+ + 
Sbjct: 954  ETTQRTYTYQAIDTHTARPPSMQVTIED-VQAQTGGTAQFEA--IIEGDPQPSVTWYKDS 1010

Query: 3089 KTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
              +  S R+          L +    + D+G Y+C A N  GQ     +L
Sbjct: 1011 VQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 3272 QTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRY 3331
            Q   T +A PP     I+DV +   G +A FEA  +   DP   V W+ +  +L    R 
Sbjct: 963  QAIDTHTARPPSMQVTIEDV-QAQTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRL 1019

Query: 3332 RTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379
                +     L + +   +++G Y C+A N  G+   KA L     +N
Sbjct: 1020 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            D    +P   QV     +   G  A +EA +   GDP     WY + V+L   +R     
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +    +L +  V + DAG+Y C A N  G
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGG 1052



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 9/117 (7%)

Query: 2346 RPEGLEKI---RELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIP 2402
            RPEGLEK    R+      F+   +      + P F + L + + +  GQ+    C++  
Sbjct: 2048 RPEGLEKEGPPRKKPGLASFRLSGLKS--WDRAPTFLRELSD-ETVVLGQSVTLACQVS- 2103

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLG 2458
               P  +  W ++   +E SSR+  +     +  +TI  V  ED GVY C  SN LG
Sbjct: 2104 -AQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALG 2159



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 5/112 (4%)

Query: 411 FDCRVTGRPYPEVTWFINDRQ-----IRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           F  +V GRP P V W   + +     I  D     + + +  H+L++ +V     G  TC
Sbjct: 5   FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 64

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           +A N +G+      L+V    +V   + V+        +G    ++A+ + T
Sbjct: 65  IASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLET 116



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP   ++  +   + G   +   +++G P+P ++W+K+G+ +     H +I   + +   
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688

Query: 325 VRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESP 358
           + ++    DSG Y   A +  G   T G + V+ P
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 723



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFV 1235
            P F++ LS+   V  G+++ L C++     P  +  W  +G  +   SR         F 
Sbjct: 2079 PTFLRELSDETVVL-GQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             L I+   + D G YT    N LG+  T+ ++R  ER
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 2/88 (2%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTL 338
            G       Q+S  P  + TW K+G  L +S++  I  T  N   L +      D G YT 
Sbjct: 2093 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 2152

Query: 339  LAENPNGCIVTSGYL-AVESPTESYVQD 365
               N  G + T+G L   E P+ S   D
Sbjct: 2153 SVSNALGTVTTTGVLRKAERPSSSPCPD 2180



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 6/77 (7%)

Query: 4430 FEVEFDGEPLPLIKWYREN------FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            F V+ +G P+P + W RE       +   ++P + + + + +  L++  V  +    +  
Sbjct: 5    FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 64

Query: 4484 VAENRGGTAKCSANLVV 4500
            +A N  G A CSA+L V
Sbjct: 65   IASNAAGQALCSASLHV 81



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP F       T E GE  +  CRVTG PKP + W  +G  +
Sbjct: 629  PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAV 670



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP     I+    +     +FE  +E   DP+  + WY++   L    R     +    S
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEG--DPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 1029

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            L + +V ++D+G Y C A N  G+   KA +
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/82 (26%), Positives = 31/82 (37%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F++   D  V  G+     C+V+ +P  + TW  +   +       I         L
Sbjct: 2078 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 2137

Query: 451  MITNVTLSDSGVVTCVARNKSG 472
             I  V   D GV TC   N  G
Sbjct: 2138 TILVVVAEDLGVYTCSVSNALG 2159



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A +E  IE  P P+  V WY +   L    R     +    +L +  V  +D+G YT
Sbjct: 987  GGTAQFEAIIEGDPQPS--VTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 1044

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            C A N  GQ +    L V   ++   DS+ +S   K+
Sbjct: 1045 CLAQNTGGQVLCKAELLVLGGDN-EPDSEKQSHRRKL 1080



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 4/95 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-GYV 2167
            P FL  L+  E +  G      C+V     P     W  +G  + +  R   +     + 
Sbjct: 2079 PTFLRELSD-ETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
             L IL   AED G Y C  +N LG    T  L+ A
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKA 2170



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFGYVA 2036
            P F + + +     G  V L   +T    P   + WY +G+ VQ   H        G  A
Sbjct: 630  PDFEEELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCA 687

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +      D+G YMC A +A G   T   + V
Sbjct: 688  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 720



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 2/100 (2%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            D    + P     + +++   G     E  ++  GD    V W+ +   +    R     
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            E    +L L  V  +D+GVYTC A N  G+ +    L V+
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 3/107 (2%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            +++    + P   V + +++  + G  A FEA +    DP   V WY +   L   +R  
Sbjct: 964  AIDTHTARPPSMQVTIEDVQ-AQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLS 1020

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
               +     L +     +D+G Y C A N  G+ +  A + V G  N
Sbjct: 1021 QQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 11/159 (6%)

Query: 3936 GMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRF---VTQIQSQTSLVEMETTK 3992
            G    E L  + + + + T++   T   + D    +PP     +  +Q+QT      T +
Sbjct: 937  GAGTGELLWDVHSHVVRETTQRTYTYQAI-DTHTARPPSMQVTIEDVQAQTG----GTAQ 991

Query: 3993 FECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATN 4052
            FE  +   GDP   V W+ +   L+   R +   +    ++    V  +D+G Y C A N
Sbjct: 992  FEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQN 1049

Query: 4053 LYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
              G    KA +   G      DS+   H + +    E++
Sbjct: 1050 TGGQVLCKAELLVLGGDN-EPDSEKQSHRRKLHSFYEVK 1087



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2919 AEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVY 2977
            ++  +V GQ + L  QV  +  P  +  W  +G  LE  SR  +++    F  L ++ V 
Sbjct: 2086 SDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVV 2143

Query: 2978 ERDSGIYTCKAYNKRGEAFTSSTV 3001
              D G+YTC   N  G   T+  +
Sbjct: 2144 AEDLGVYTCSVSNALGTVTTTGVL 2167



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P   PP F  EL   T    G+T    C+V     P   I +Y +GKA+Q      +  D
Sbjct: 625  PVWRPPDFEEELADCTAEL-GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIED 681

Query: 2297 -FGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              G  +L +      D+G+Y   A +A G+C++
Sbjct: 682  PDGSCALILDSLTGVDSGQYMCFAASAAGNCST 714



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A FE  +E   DP  ++ W+ +  ++    R     +    +L + +  ++D+G Y 
Sbjct: 987  GGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 1044

Query: 2184 CKATNKLGEAVNTCTLKVAGHRN 2206
            C A N  G+ +    L V G  N
Sbjct: 1045 CLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 3/122 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P F    SD  +    S    C++      + +  W  +G PL + SRV        F +
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V   D G+YTC  +N  G  T +  L+   R      P +   +  G   + K  
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPV 2196

Query: 3677 ET 3678
            E+
Sbjct: 2197 ES 2198



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 4/88 (4%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF-GYV 2300
            P F+ EL   T V  G++    CQV     P  +  +  +G  L+S++R  I+     + 
Sbjct: 2079 PTFLRELSDETVVL-GQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTS 2328
             L I   V ED G Y+    NALG  T+
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTT 2163



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG-HR 1358
            Q R  + V + P F   L +     G  V L CR+   G     + W+ +GK ++   H 
Sbjct: 619  QQRLALPVWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHH 676

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                      AL L S+   DSG Y C A +  G   T
Sbjct: 677  ILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCST 714



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 943  VEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+ V+     I      G  AL + S+T  D+G Y C A +A G  +T   + +
Sbjct: 661  ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 720


>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
            calmodulin and titin-interacting RhoGEF protein.
          Length = 2582

 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 8/194 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP+  E L D     G+ ++ +C++ G P P + WYK  K ++   +  +    D     
Sbjct: 629  PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688

Query: 4682 ISEAFPE-DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I ++    D G Y C A ++AG  +   K+ V  P +  N    +P       EG+ AQF
Sbjct: 689  ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPF-----VEGEDAQF 743

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRATTA 4798
               I     P I+W ++GAL+     FQ + E  +   VL+I    +ED G + C     
Sbjct: 744  TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 803

Query: 4799 AGQVETSAKLVVKS 4812
             G    SA+L ++S
Sbjct: 804  LGSARASAELRIQS 817



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIRNKILEE-DGTYT 4570
            PP F     +     G+ V+L  +VTGT KP+ + W K+GK VQ D  + ++E+ DG+  
Sbjct: 629  PPDFEEELADCTAELGETVKLACRVTGTPKPV-ISWYKDGKAVQVDPHHILIEDPDGSCA 687

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L++      DSG+Y C A ++AG      + +V +P                P  +  ++
Sbjct: 688  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP----------------PRFVNKVR 731

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--MSRTADEYTLRISEAFPE 4688
                 EG+  +F+C I G P P ++WYK   L+     FQ      +    L I  A  E
Sbjct: 732  ASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKE 791

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            D G Y+C   N  G    +A+L++  P
Sbjct: 792  DLGLYECELVNRLGSARASAELRIQSP 818



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F +   D     G+  +  CRVTG P P ++W+ + + ++ D +H ++ +  G+ AL+
Sbjct: 630 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 689

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           + ++T  DSG   C A + +G  +   ++ V      V P+FV +       EGE     
Sbjct: 690 LDSLTGVDSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFT 744

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVA 569
               G P P+I W KDG  +    + +  ++   G   L I  A   D   Y+C   N  
Sbjct: 745 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 804

Query: 570 GSTATRARL 578
           GS    A L
Sbjct: 805 GSARASAEL 813



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 42/143 (29%), Positives = 77/143 (53%), Gaps = 8/143 (5%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V   PRF+ ++   +   EG+ A + C IE  P P +R  WY +G +L +G++++T 
Sbjct: 717  KILVQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTL 773

Query: 1897 ND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
            ++   G   L I     ED G Y C+ +N LG A +S  L +QS    +  +Q +   E+
Sbjct: 774  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHREQ 830

Query: 1955 IQYLEDDSRYKRAVQDDSFVVEK 1977
            +    +D+  +RA Q+ + V+++
Sbjct: 831  LVAAVEDTTLERADQEVTSVLKR 853



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 13/201 (6%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQIHTFSTKSI 4467
            +PP F +++  C     E  +      G P P+I WY++   ++  P    I        
Sbjct: 628  RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI+  +   DS  +   A +  G       ++V+          VPP F    +      
Sbjct: 688  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----------VPPRFVNKVRASPFVE 737

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLILEAYPQDSGKYE 4585
            G+  +    + G     + W K+G  +    + + L E   G   L+I  A  +D G YE
Sbjct: 738  GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 797

Query: 4586 CVAINSAGEARCDAECVVSLP 4606
            C  +N  G AR  AE  +  P
Sbjct: 798  CELVNRLGSARASAELRIQSP 818



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 7/136 (5%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
           PP+   K R S   EG DAQF   + G P P++ W+K+G  L   NK + ++        
Sbjct: 723 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 782

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP-TESYVQDQRSQYIT----DTQQR 377
           L +R   K D G Y     N  G    S  L ++SP  ++  Q  R Q +      T +R
Sbjct: 783 LVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLER 842

Query: 378 ETEERIEISEKALAPQ 393
             +E   + ++ L P+
Sbjct: 843 ADQEVTSVLKRLLGPK 858



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 57/233 (24%), Positives = 90/233 (38%), Gaps = 14/233 (6%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS-HRIRTVYAFG 3104
            RPP+F    +++ D +       + +   TG    VI W+ +GK ++   H I      G
Sbjct: 628  RPPDFE---EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG 684

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +      DSG Y C A +  G      K+          PRF   ++      +G
Sbjct: 685  SCALILDSLTGVDSGQYMCFAASAAGNCSTLGKI-----LVQVPPRFVNKVR-ASPFVEG 738

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEY 3222
            + A F CT+     P  +I WY +G  +    + +T+S+   G +VL I      D G Y
Sbjct: 739  EDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 796

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPS 3275
             C   N+ G     A +          E    + L    E  +L+ A Q+  S
Sbjct: 797  ECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTS 849



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 5/113 (4%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD- 3883
            +V  PP+F+ ++++    E E  +F C +E    P++R  WY++G LL +G++++T+ + 
Sbjct: 719  LVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 776

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              G + L I     ED G Y C  VN  G     A +  +  P +  Q Q  R
Sbjct: 777  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS-PMLQAQEQCHR 828



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  +   ++ +   GG A+FE  + G+P P V+W +    LV+  + S +    T   S
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTT--YS 1029

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAIC 157
            L+++ +   D G YTC A+N  G+ +C
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLC 1056



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 28/91 (30%), Positives = 48/91 (52%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP +     + + Q G  AQF+  + G+P+P VTW+K+  +L++S +          +L 
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            +R+    D+G YT LA+N  G ++    L V
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 5/115 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            VQ  P F   +++    VEG+       +E    P  +I W+K+G  LTTG + ++  + 
Sbjct: 720  VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEP 776

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
              GL+ L I +   +D G+Y C+  N LG A ++A ++I+       E  H + L
Sbjct: 777  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL 831



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 38/138 (27%), Positives = 66/138 (47%), Gaps = 10/138 (7%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD- 1498
            V + PRFV + ++    +EG+   F C +E      ++  W+K+G  +T G++F+ + + 
Sbjct: 720  VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 776

Query: 1499 -FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
              G + L I     ED G+Y C  VN +G+   S  L  +S    +   Q +   EQ+  
Sbjct: 777  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHREQLVA 833

Query: 1558 LEDRSKYHRTDMVDEVTT 1575
              + +   R D   EVT+
Sbjct: 834  AVEDTTLERAD--QEVTS 849



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 2/111 (1%)

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751
            E T +   + A D    + P   + ++D++      A FEA  I  GDP+  V W ++ V
Sbjct: 954  ETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKDSV 1011

Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             +  S RL+   +    +L +++V  +D+G YTC A N  G+ +  + L V
Sbjct: 1012 QLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 25/93 (26%), Positives = 47/93 (50%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++PP     ++  +      A+FE   +G+P P + WY+++  + +S         T   
Sbjct: 970  ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 1029

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
            L++R V  +D+ V+  +A+N GG   C A L+V
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 26/91 (28%), Positives = 46/91 (50%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PPS  +T ++V   +G   + +  + G     V W K+  ++    R    +E  TY+L+
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            +     +D+G Y C+A N+ G+  C AE +V
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 1/125 (0%)

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
            T   + D  S  + +T QR    +   +  A  P      +D     G   +F+  + G 
Sbjct: 940  TGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGD 999

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
            P P VTW+ +  Q+ D         E   ++L++ +V   D+GV TC+A+N  G+   + 
Sbjct: 1000 PQPSVTWYKDSVQLVDS-TRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKA 1058

Query: 479  RLNVI 483
             L V+
Sbjct: 1059 ELLVL 1063



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--H 4460
            G +    PP F  K++     E E A+F    +G P P I+WY++   +     FQ    
Sbjct: 716  GKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 775

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              S   +L+IR    ED  ++     NR G+A+ SA L ++    Q +
Sbjct: 776  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQ 823



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 5/95 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FGF 1234
            P FV  +   P V EG++    C +E  G P  ++ W+ +G  +T G++F+T  +   G 
Sbjct: 724  PRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 780

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            + L I  A+  D G Y    VN LGSA  SA +R+
Sbjct: 781  LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 36/134 (26%), Positives = 67/134 (50%), Gaps = 11/134 (8%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FG 3338
            PP+F+ +++  +  VEG+ A F   +     P ++  W+ +G  L  G++++T  +   G
Sbjct: 723  PPRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 779

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398
            +++L I    +E+ G YEC   N+LG     A L+  S    +L +Q     E   + + 
Sbjct: 780  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHRE---QLVA 833

Query: 3399 TLEDSMVRRKDTSV 3412
             +ED+ + R D  V
Sbjct: 834  AVEDTTLERADQEV 847



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND--FG 3751
            PPRF  +++ +  V EG    F C +E  G P  +I W+ +G    TG++  TL++   G
Sbjct: 723  PPRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 779

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + L I      D G Y C   N+ GSA  +A++
Sbjct: 780  LLVLVIRAASKEDLGLYECELVNRLGSARASAEL 813



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            ++I+  T++ P     ++D+ + Q G  A FEA +    DP   V WYKD   +  S+R+
Sbjct: 963  QAIDTHTARPPSMQVTIEDV-QAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRL 1019

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +        SL + H+ ++DAG YT  A N  G+ +  A + V
Sbjct: 1020 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/95 (29%), Positives = 42/95 (44%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP +   ++D     G   +F   I G P P+V WYK    +  S      +    Y+L 
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            +     +D G Y C+A N+ G+V   A+L V   D
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGD 1066



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            + + P  +  I+D +  + GG A FEA +E  GD    V W KD   +  S+R++     
Sbjct: 969  TARPPSMQVTIED-VQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEG 1025

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
               +L ++ V   DAG YTC A N  GQ    A L ++
Sbjct: 1026 TTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 9/130 (6%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND--FGF 3614
            PP F          E   A F C +       +R  W+ +G  L TG++ +T+++   G 
Sbjct: 723  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 780

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
            ++L I    + D GLY C+  NR G A  S +L++   Q  +L+ Q   H +    +++ 
Sbjct: 781  LVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLVAAVE- 836

Query: 3675 LEETLHKREE 3684
             + TL + ++
Sbjct: 837  -DTTLERADQ 845



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 13/179 (7%)

Query: 1701 SAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            S   +++ Q P  F   ++     E + A F   +   G P  ++ W ++G  +   N+ 
Sbjct: 713  STLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKF 770

Query: 1760 TTMHD--FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESA 1817
             T+ +   G + L ++  + ED G Y C  +N LG A  S+ L +QS      E  H   
Sbjct: 771  QTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHRE- 829

Query: 1818 LQKIQQLEDSSRYQRREDVEVAVN-----QAPRFIT-QLNGPTKLSEGQSAHYECRIEP 1870
             Q +  +ED++  +  ++V   +      +AP   T  L GP     G  A  E   +P
Sbjct: 830  -QLVAAVEDTTLERADQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQP 887



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%)

Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448
            Q G TA F+   I  GDP   V W+++   + DS+R+++  +    S+ + HV  +D GV
Sbjct: 985  QTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGV 1042

Query: 2449 YMCRASNLLGE 2459
            Y C A N  G+
Sbjct: 1043 YTCLAQNTGGQ 1053



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 8/127 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V   P+F   +     VEG +    C ++  G    ++ W+ +G  + TG++F+   E
Sbjct: 718  ILVQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSE 775

Query: 1365 --FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK-I 1421
                 + L + +   ED G+Y C+  N+LG A  S  LR+   +  +L++Q     E+ +
Sbjct: 776  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLV 832

Query: 1422 QYLEDTS 1428
              +EDT+
Sbjct: 833  AAVEDTT 839



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRL--QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF- 1365
            +AP F R L +   V G +V L C++  QP    T    W  +G P+++  R   +    
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQAT----WSKDGAPLESSSRVLISATLK 2132

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
            ++  L +L V  ED GVYTC  +N LG   T+  LR
Sbjct: 2133 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 26/104 (25%), Positives = 39/104 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P        +  + G      A   G P P +TW KD V ++ +  L    +G   +L +
Sbjct: 973  PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVL 1032

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLH 594
                + DA  Y C AQN  G    +A L           +K+ H
Sbjct: 1033 RHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQSH 1076



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 6/107 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT-SIFNFGYV 828
            P F+R L D   +  G++     Q++  + P  +  W KDG P+ +SSR+  S     + 
Sbjct: 2079 PTFLRELSD-ETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR--STVTADLG 873
             L I+ + AED G YT    N LG   +T  +R A R  S+   D+G
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIG 2182



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSG 3491
            EGE+A F   +     P ++  WY +G  L  G++F+T  +   G ++L I     ED G
Sbjct: 737  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 3492 EYLCRAYNNYGEAVTTASMKVQ 3513
             Y C   N  G A  +A +++Q
Sbjct: 795  LYECELVNRLGSARASAELRIQ 816



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746
            I+     PP   V I+D +    GG   F+  +E  GDP   + W+ +       +R+  
Sbjct: 965  IDTHTARPPSMQVTIED-VQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQ 1021

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
              +    +L + ++ ++DAG YTC A N  G     A++
Sbjct: 1022 QQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ +   PRF+  ++ +   VEG+ A F   +E        + WY +G  +T+ N+ QT 
Sbjct: 717  KILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAP--YPQIRWYKDGALLTTGNKFQTL 773

Query: 1096 HD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             +   G + L I +   ED G+Y     N  G A+ SA + +++         HR
Sbjct: 774  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 828



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP   V ++ V A  GG   FE  IE  GDP   + W K+   +  S+R +        S
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 1029

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +  +  +D+G YTC A +  G    KA L V
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 22/84 (26%), Positives = 40/84 (47%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + D+    G  AQF+  I    +P++ W ++   + ++       EG    L++ +   +
Sbjct: 979  IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASK 1038

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            D G +TC A    GQV   A+L+V
Sbjct: 1039 DAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 5/96 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FG 2298
            PPRFV ++R +  V EG+ A F C +E    P +R  +Y +G  L +  +F    +   G
Sbjct: 723  PPRFVNKVRASPFV-EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 779

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             + L I+    ED G Y  + +N LG   ++  + +
Sbjct: 780  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/92 (28%), Positives = 43/92 (46%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F    + + F +G +A+F   + G P P + W +  A L   NK+      ++G + 
Sbjct: 723 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 782

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L+I+     D G Y C   N+ G A  S  ++
Sbjct: 783 LVIRAASKEDLGLYECELVNRLGSARASAELR 814



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSG 2180
            EG+ A F C +E    P+  I W+ +G  +  G++++T  +   G + L I     ED G
Sbjct: 737  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
             Y C+  N+LG A  +  L++
Sbjct: 795  LYECELVNRLGSARASAELRI 815



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            + ++  + G    FE  +E   DP   + W+ ++  L   TR     + +  SL + H  
Sbjct: 979  IEDVQAQTGGTAQFEAIIEG--DPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVA 1036

Query: 2840 EEDSGIYTCKATNSKGSATTSGSLRCTGDKN 2870
             +D+G+YTC A N+ G       L   G  N
Sbjct: 1037 SKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/81 (30%), Positives = 47/81 (58%), Gaps = 6/81 (7%)

Query: 4639 AIEFSCKIVGKPLPTVQWYK-----GDKLIKP-SKYFQMSRTADEYTLRISEAFPEDEGD 4692
            +I FS K+ G+P+PTV W +     G   I P +  + ++ +A +++L + +   + +G 
Sbjct: 2    SITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGT 61

Query: 4693 YKCVAYNSAGRVTVAAKLKVT 4713
            Y C+A N+AG+   +A L V+
Sbjct: 62   YTCIASNAAGQALCSASLHVS 82



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--R 690
           V  PP+F+  +++   +EG    F   IE  G P  +I W K+G  +   ++F ++   R
Sbjct: 720 VQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPR 777

Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQL 750
            G + L + + + +D G Y C  V+  G A   A L +       +   H E  Q +  +
Sbjct: 778 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHRE--QLVAAV 835

Query: 751 ED 752
           ED
Sbjct: 836 ED 837



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 1/107 (0%)

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
            K+ +  P  +  L D+ V  GQ++  +C++  +P     W K    ++ S    +S T  
Sbjct: 2073 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 2132

Query: 4677 EY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
             +  L I     ED G Y C   N+ G VT    L+  +   +   P
Sbjct: 2133 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCP 2179



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/56 (42%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 945  WLKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            W KDG P+E+SSR+        +  LTI  V   D G YTC   NA+G  TT+  L
Sbjct: 2112 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 2167



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-F 691
           V+ PP F   L   TA  G  +    R+   G P   I W K+G++++       I    
Sbjct: 626 VWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPD 683

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
           G  +L + SL   DSG+Y C A SA G   T  K ++ V PR
Sbjct: 684 GSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPR 725



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 4/92 (4%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF- 1899
            ++AP F+ +L+  T +  GQS    C++     P  +  W  +G  L+S  R   S    
Sbjct: 2076 DRAPTFLRELSDETVVL-GQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLK 2132

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             F  L IL V  ED G YTC   N LG   ++
Sbjct: 2133 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTT 2164



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            F+  L++     G ++   C V  S  P  +  W  +  PL S +R   +    ++  L 
Sbjct: 2081 FLRELSDETVVLGQSVTLACQV--SAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 2138

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            I     ED G+YTC  +N+ G+ TT+G LR
Sbjct: 2139 ILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN--FGY 827
           P+F+  ++      EG +A F   +     P +R  WYKDG  +T  ++  ++     G 
Sbjct: 724 PRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 780

Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           + L I     ED G Y    VN+LG A ++A +R+
Sbjct: 781 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 8/101 (7%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTF-D 2696
            +AP F   L S + +V GQ V L  QV  +  P  +  W K+G  L + +R  + +T  +
Sbjct: 2077 RAPTFLREL-SDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKN 2133

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            F L+T+ +  +  +D G+YTC  +N LG   +T  ++  +R
Sbjct: 2134 FQLLTILV--VVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAG 980
            EG  A F   +E  G    ++ W KDG  +   ++  T      G + L I++ +  D G
Sbjct: 737  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKIT 1040
             Y C   N +G A  SA L I +      E  H   L  +  +ED +   +R ++EV   
Sbjct: 795  LYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL--VAAVEDTT--LERADQEVTSV 850

Query: 1041 QKPRFLGP 1048
             K R LGP
Sbjct: 851  LK-RLLGP 857



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
            G +A FEA +E   D   +V WY +  Q+  + R+    +    +L +  V ++D+GVYT
Sbjct: 987  GGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 1044

Query: 1118 VVARNAAGEAQLSASMTV 1135
             +A+N  G+    A + V
Sbjct: 1045 CLAQNTGGQVLCKAELLV 1062



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 6/77 (7%)

Query: 4740 FKTQITSKIKPTIQWLREGA------LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            F  ++  +  PT+ WLRE A      + P+TP + +        L++ +   +  GT+TC
Sbjct: 5    FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 64

Query: 4794 RATTAAGQVETSAKLVV 4810
             A+ AAGQ   SA L V
Sbjct: 65   IASNAAGQALCSASLHV 81



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GY 1767
            +AP F   + D  V   Q+     ++     P  +  W ++G P+E+S+R+        +
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNF 2134

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
              L +  V  ED G YTC   N LG   T+  L
Sbjct: 2135 QLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 2167



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYV 2035
            P+F   ++ +   EG       T+     P +R  WY +G  +  G++F+T  +   G +
Sbjct: 724  PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLL 781

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
             L I  A  ED G Y C+  N +G A  ++ +++ +
Sbjct: 782  VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 817



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 2/101 (1%)

Query: 3551 EAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN 3610
            +  +  PP    T  D+      +A FE   I   D    V W+ +   L+  +R+    
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            +     L +  V  +DAG+YTC A N  G+     +L V G
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLG 1064



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 9/129 (6%)

Query: 2621 LKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFK 2680
            ++E          +DT   + P     ++       G   + EA +E   DP   + W+K
Sbjct: 952  VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQF-EAIIEG--DPQPSVTWYK 1008

Query: 2681 NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL 2740
            + V L    RL    +    +L +  + + D+G+YTC A N  G+ +  A + +      
Sbjct: 1009 DSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV------ 1062

Query: 2741 LGESLHPDS 2749
            LG    PDS
Sbjct: 1063 LGGDNEPDS 1071



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 8/91 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV---HTLNDFG 3751
            P F  E+ D   V  G  V   C+V     P  +  W  +G P  + SRV    TL +F 
Sbjct: 2079 PTFLRELSDET-VVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
             + + +  + A D G YTC  +N  G+ TTT
Sbjct: 2136 LLTILV--VVAEDLGVYTCSVSNALGTVTTT 2164



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFV 3887
            PP F  ++   T E  E V+  CRV     PK  I WY++GK +     +  + D  G  
Sbjct: 629  PPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 686

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +L +  +   DSG+Y+C A +  G   T   I  +  P  +
Sbjct: 687  ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFV 727



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP FE+   +     G   K   ++ G P PV+SW  K    V+ + + +   +  G  +
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISW-YKDGKAVQVDPHHILIEDPDGSCA 687

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L++  +   D G+Y C A +  G
Sbjct: 688 LILDSLTGVDSGQYMCFAASAAG 710



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EG++  F C +E +  P  +I W+ +   L +G ++++  +     + L I    +ED G
Sbjct: 737  EGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 2845 IYTCKATNSKGSATTSGSLR 2864
            +Y C+  N  GSA  S  LR
Sbjct: 795  LYECELVNRLGSARASAELR 814



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG+ A +   +     P +R  WY +G  L  G++F+T  +   G + L I +    D G
Sbjct: 737  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 2580 LYMCKAINRAG 2590
            LY C+ +NR G
Sbjct: 795  LYECELVNRLG 805



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 91  FEGKLRGNPTPVVSWTRKKAPL------VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           F  K+ G P P V W R++A         +   Y++  + Q    SL++  +G   +G Y
Sbjct: 5   FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH--SLVLLDVGRQHQGTY 62

Query: 145 TCTARNQYGEAICSVYIQPEG 165
           TC A N  G+A+CS  +   G
Sbjct: 63  TCIASNAAGQALCSASLHVSG 83



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 2/113 (1%)

Query: 1557 VLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            V E   + +    +D  T + P    ++++V+ + G  A FE   I   D    V WY +
Sbjct: 952  VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKD 1009

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            +  L   +R ++       +L +     +D+G YTC A N  G+ +     +V
Sbjct: 1010 SVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 4/108 (3%)

Query: 468  RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
            R K G  +F  RL+ + K    AP F+   S   V  G+ V L  +    P  + TW KD
Sbjct: 2059 RKKPGLASF--RLSGL-KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKD 2115

Query: 528  GVPIIPNPELRIH-TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            G P+  +  + I  T      L I    A D   Y C+  N  G+  T
Sbjct: 2116 GAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTT 2163



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYVA 2036
            P F + + +  V  G  V L   ++    P  +  W  +G P++   R   +     +  
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            L IL   AED G Y C  +NA+G   TT  ++
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
            + +D    + P     I++++  + G +A FE  +    DP   + WY +   +  STR+
Sbjct: 963  QAIDTHTARPPSMQVTIEDVQA-QTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRL 1019

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
                +     L + +  + D+G Y C A N  G+   +A +   G
Sbjct: 1020 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLG 1064



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGF 3752
            PP F  E+ D      G  V   CRV   G P   I W+ +G+          + D  G 
Sbjct: 629  PPDFEEELAD-CTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGS 685

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             AL +D +   D+G+Y C A +  G+ +T  KI
Sbjct: 686  CALILDSLTGVDSGQYMCFAASAAGNCSTLGKI 718



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYV 1502
            P F+ R  S E V+ GQ V   C++        +  W K+G P+    R         + 
Sbjct: 2079 PTFL-RELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGT 1527
             L I+ ++AED G+YTC   N +GT
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGT 2160



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP FV+   A    EGE A+F C + G P P++ W  +G  +  G++++
Sbjct: 723  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 771



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/97 (28%), Positives = 40/97 (41%), Gaps = 3/97 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P F+ ++   TV   + V   C+V  +  P  +  W ++G  L S  R      +  F  
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L IL V AED G Y C   N  G   T   +   + P
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERP 2173



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 1613 WYHNNKPLKSGSRFTETNNF-GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666
            W  +  PL+S SR   +     F  L I+  + ED G YTC   NALG   T+G+
Sbjct: 2112 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGV 2166



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 7/90 (7%)

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKK-----VQPDIRNKILEEDGT-YTLLILEAYPQDSGKY 4584
            +    KV G     V+WL+   +     + PD     +      ++L++L+   Q  G Y
Sbjct: 3    ITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTY 62

Query: 4585 ECVAINSAGEARCDAECVVS-LPATKDKPK 4613
             C+A N+AG+A C A   VS LP  +++ K
Sbjct: 63   TCIASNAAGQALCSASLHVSGLPKVEEQEK 92



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            Q  +A+ K   +++    Q+R  + + V + P F  +L   T    G++    CR+   P
Sbjct: 601  QARTAIIKSSWVKEICGIQQR--LALPVWRPPDFEEELADCTA-ELGETVKLACRVTGTP 657

Query: 1873 DPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             P   + WY +GK +Q   H     +  G  AL + ++ G DSG+Y C A +  G   + 
Sbjct: 658  KPV--ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTL 715

Query: 1932 IRLNVQ 1937
             ++ VQ
Sbjct: 716  GKILVQ 721



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 2/104 (1%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            DT   +P  +     + Q   G     E  +E   DP   + WY +   L   +R     
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            +    +L L  V  +D+G+YTC A N  G+    + +     DN
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR-FTSIFRFGYIS 695
            P F+  L   T + G  +    ++     P  +  W K+G  +E+SSR   S     +  
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L +L +  +D G YTC   +A G   T  VL    R
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 3/110 (2%)

Query: 3029 EDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG 3088
            E + R    Q  D  T RPP      +D V    G  A +EA  I  GD    + W+ + 
Sbjct: 954  ETTQRTYTYQAIDTHTARPPSMQVTIED-VQAQTGGTAQFEA--IIEGDPQPSVTWYKDS 1010

Query: 3089 KTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
              +  S R+          L +    + D+G Y+C A N  GQ     +L
Sbjct: 1011 VQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 3272 QTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRY 3331
            Q   T +A PP     I+DV +   G +A FEA  +   DP   V W+ +  +L    R 
Sbjct: 963  QAIDTHTARPPSMQVTIEDV-QAQTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRL 1019

Query: 3332 RTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379
                +     L + +   +++G Y C+A N  G+   KA L     +N
Sbjct: 1020 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            D    +P   QV     +   G  A +EA +   GDP     WY + V+L   +R     
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +    +L +  V + DAG+Y C A N  G
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGG 1052



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 9/117 (7%)

Query: 2346 RPEGLEKI---RELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIP 2402
            RPEGLEK    R+      F+   +      + P F + L + + +  GQ+    C++  
Sbjct: 2048 RPEGLEKEGPPRKKPGLASFRLSGLKS--WDRAPTFLRELSD-ETVVLGQSVTLACQVS- 2103

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLG 2458
               P  +  W ++   +E SSR+  +     +  +TI  V  ED GVY C  SN LG
Sbjct: 2104 -AQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALG 2159



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 5/112 (4%)

Query: 411 FDCRVTGRPYPEVTWFINDRQ-----IRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           F  +V GRP P V W   + +     I  D     + + +  H+L++ +V     G  TC
Sbjct: 5   FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 64

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           +A N +G+      L+V    +V   + V+        +G    ++A+ + T
Sbjct: 65  IASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLET 116



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP   ++  +   + G   +   +++G P+P ++W+K+G+ +     H +I   + +   
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688

Query: 325 VRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESP 358
           + ++    DSG Y   A +  G   T G + V+ P
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 723



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFV 1235
            P F++ LS+   V  G+++ L C++     P  +  W  +G  +   SR         F 
Sbjct: 2079 PTFLRELSDETVVL-GQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             L I+   + D G YT    N LG+  T+ ++R  ER
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 2/88 (2%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTL 338
            G       Q+S  P  + TW K+G  L +S++  I  T  N   L +      D G YT 
Sbjct: 2093 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 2152

Query: 339  LAENPNGCIVTSGYL-AVESPTESYVQD 365
               N  G + T+G L   E P+ S   D
Sbjct: 2153 SVSNALGTVTTTGVLRKAERPSSSPCPD 2180



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 6/77 (7%)

Query: 4430 FEVEFDGEPLPLIKWYREN------FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            F V+ +G P+P + W RE       +   ++P + + + + +  L++  V  +    +  
Sbjct: 5    FSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 64

Query: 4484 VAENRGGTAKCSANLVV 4500
            +A N  G A CSA+L V
Sbjct: 65   IASNAAGQALCSASLHV 81



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP F       T E GE  +  CRVTG PKP + W  +G  +
Sbjct: 629  PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAV 670



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP     I+    +     +FE  +E   DP+  + WY++   L    R     +    S
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEG--DPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 1029

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            L + +V ++D+G Y C A N  G+   KA +
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/82 (26%), Positives = 31/82 (37%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F++   D  V  G+     C+V+ +P  + TW  +   +       I         L
Sbjct: 2078 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 2137

Query: 451  MITNVTLSDSGVVTCVARNKSG 472
             I  V   D GV TC   N  G
Sbjct: 2138 TILVVVAEDLGVYTCSVSNALG 2159



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A +E  IE  P P+  V WY +   L    R     +    +L +  V  +D+G YT
Sbjct: 987  GGTAQFEAIIEGDPQPS--VTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 1044

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            C A N  GQ +    L V   ++   DS+ +S   K+
Sbjct: 1045 CLAQNTGGQVLCKAELLVLGGDN-EPDSEKQSHRRKL 1080



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 4/95 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-GYV 2167
            P FL  L+  E +  G      C+V     P     W  +G  + +  R   +     + 
Sbjct: 2079 PTFLRELSD-ETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
             L IL   AED G Y C  +N LG    T  L+ A
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKA 2170



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFGYVA 2036
            P F + + +     G  V L   +T    P   + WY +G+ VQ   H        G  A
Sbjct: 630  PDFEEELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCA 687

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +      D+G YMC A +A G   T   + V
Sbjct: 688  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 720



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 2/100 (2%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            D    + P     + +++   G     E  ++  GD    V W+ +   +    R     
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            E    +L L  V  +D+GVYTC A N  G+ +    L V+
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 3/107 (2%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            +++    + P   V + +++  + G  A FEA +    DP   V WY +   L   +R  
Sbjct: 964  AIDTHTARPPSMQVTIEDVQ-AQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLS 1020

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
               +     L +     +D+G Y C A N  G+ +  A + V G  N
Sbjct: 1021 QQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 11/159 (6%)

Query: 3936 GMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRF---VTQIQSQTSLVEMETTK 3992
            G    E L  + + + + T++   T   + D    +PP     +  +Q+QT      T +
Sbjct: 937  GAGTGELLWDVHSHVVRETTQRTYTYQAI-DTHTARPPSMQVTIEDVQAQTG----GTAQ 991

Query: 3993 FECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATN 4052
            FE  +   GDP   V W+ +   L+   R +   +    ++    V  +D+G Y C A N
Sbjct: 992  FEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQN 1049

Query: 4053 LYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
              G    KA +   G      DS+   H + +    E++
Sbjct: 1050 TGGQVLCKAELLVLGGDN-EPDSEKQSHRRKLHSFYEVK 1087



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2919 AEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVY 2977
            ++  +V GQ + L  QV  +  P  +  W  +G  LE  SR  +++    F  L ++ V 
Sbjct: 2086 SDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVV 2143

Query: 2978 ERDSGIYTCKAYNKRGEAFTSSTV 3001
              D G+YTC   N  G   T+  +
Sbjct: 2144 AEDLGVYTCSVSNALGTVTTTGVL 2167



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P   PP F  EL   T    G+T    C+V     P   I +Y +GKA+Q      +  D
Sbjct: 625  PVWRPPDFEEELADCTAEL-GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIED 681

Query: 2297 -FGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              G  +L +      D+G+Y   A +A G+C++
Sbjct: 682  PDGSCALILDSLTGVDSGQYMCFAASAAGNCST 714



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A FE  +E   DP  ++ W+ +  ++    R     +    +L + +  ++D+G Y 
Sbjct: 987  GGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 1044

Query: 2184 CKATNKLGEAVNTCTLKVAGHRN 2206
            C A N  G+ +    L V G  N
Sbjct: 1045 CLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 3/122 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P F    SD  +    S    C++      + +  W  +G PL + SRV        F +
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V   D G+YTC  +N  G  T +  L+   R      P +   +  G   + K  
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPV 2196

Query: 3677 ET 3678
            E+
Sbjct: 2197 ES 2198



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 4/88 (4%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF-GYV 2300
            P F+ EL   T V  G++    CQV     P  +  +  +G  L+S++R  I+     + 
Sbjct: 2079 PTFLRELSDETVVL-GQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTS 2328
             L I   V ED G Y+    NALG  T+
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTT 2163



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG-HR 1358
            Q R  + V + P F   L +     G  V L CR+   G     + W+ +GK ++   H 
Sbjct: 619  QQRLALPVWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHH 676

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                      AL L S+   DSG Y C A +  G   T
Sbjct: 677  ILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCST 714



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 943  VEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+ V+     I      G  AL + S+T  D+G Y C A +A G  +T   + +
Sbjct: 661  ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 720


>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
          Length = 1020

 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 8/194 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP+  E L D     G+ ++ +C++ G P P + WYK  K ++   +  +    D     
Sbjct: 413  PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 472

Query: 4682 ISEAFPE-DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I ++    D G Y C A ++AG  +   K+ V  P +  N    +P       EG+ AQF
Sbjct: 473  ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPF-----VEGEDAQF 527

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRATTA 4798
               I     P I+W ++GAL+     FQ + E  +   VL+I    +ED G + C     
Sbjct: 528  TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 587

Query: 4799 AGQVETSAKLVVKS 4812
             G    SA+L ++S
Sbjct: 588  LGSARASAELRIQS 601



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIRNKILEE-DGTYT 4570
            PP F     +     G+ V+L  +VTGT KP+ + W K+GK VQ D  + ++E+ DG+  
Sbjct: 413  PPDFEEELADCTAELGETVKLACRVTGTPKPV-ISWYKDGKAVQVDPHHILIEDPDGSCA 471

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L++      DSG+Y C A ++AG      + +V +P                P  +  ++
Sbjct: 472  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP----------------PRFVNKVR 515

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--MSRTADEYTLRISEAFPE 4688
                 EG+  +F+C I G P P ++WYK   L+     FQ      +    L I  A  E
Sbjct: 516  ASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKE 575

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            D G Y+C   N  G    +A+L++  P
Sbjct: 576  DLGLYECELVNRLGSARASAELRIQSP 602



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F +   D     G+  +  CRVTG P P ++W+ + + ++ D +H ++ +  G+ AL+
Sbjct: 414 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 473

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           + ++T  DSG   C A + +G  +   ++ V      V P+FV +       EGE     
Sbjct: 474 LDSLTGVDSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFT 528

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVA 569
               G P P+I W KDG  +    + +  ++   G   L I  A   D   Y+C   N  
Sbjct: 529 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 588

Query: 570 GSTATRARL 578
           GS    A L
Sbjct: 589 GSARASAEL 597



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 38/130 (29%), Positives = 68/130 (52%), Gaps = 6/130 (4%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V   PRF+ ++   +   EG+ A + C IE  P P +R  WY +G +L +G++++T 
Sbjct: 501  KILVQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTL 557

Query: 1897 ND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH-ESALE 1953
            ++   G   L I     ED G Y C+ +N LG A +S  L +QS     ++  H E  + 
Sbjct: 558  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVA 617

Query: 1954 KIQYLEDDSR 1963
             ++  E +++
Sbjct: 618  AVEVTEQETK 627



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 13/222 (5%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD-FQIHTFSTKSI 4467
            +PP F +++  C     E  +      G P P+I WY++   ++  P    I        
Sbjct: 412  RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 471

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI+  +   DS  +   A +  G       ++V+          VPP F    +      
Sbjct: 472  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----------VPPRFVNKVRASPFVE 521

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLILEAYPQDSGKYE 4585
            G+  +    + G     + W K+G  +    + + L E   G   L+I  A  +D G YE
Sbjct: 522  GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 581

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            C  +N  G AR  AE  +  P  + + +   +   A  E+ E
Sbjct: 582  CELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 623



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 6/133 (4%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD- 3883
            +V  PP+F+ ++++    E E  +F C +E    P++R  WY++G LL +G++++T+ + 
Sbjct: 503  LVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 560

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR-GMKRSE 3941
              G + L I     ED G Y C  VN  G     A +  +  P +  Q Q  R  +  + 
Sbjct: 561  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS-PMLQAQEQCHREQLVAAV 619

Query: 3942 ALTQMEATIKKYT 3954
             +T+ E  + K T
Sbjct: 620  EVTEQETKVPKKT 632



 Score = 63.3 bits (147), Expect = 2e-08
 Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 3/122 (2%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
           PP+   K R S   EG DAQF   + G P P++ W+K+G  L   NK + ++        
Sbjct: 507 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 566

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP-TESYVQDQRSQYITDTQQRETEE 381
           L +R   K D G Y     N  G    S  L ++SP  ++  Q  R Q +   +  E E 
Sbjct: 567 LVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQET 626

Query: 382 RI 383
           ++
Sbjct: 627 KV 628



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 49/189 (25%), Positives = 77/189 (40%), Gaps = 14/189 (7%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS-HRIRTVYAFG 3104
            RPP+F    +++ D +       + +   TG    VI W+ +GK ++   H I      G
Sbjct: 412  RPPDFE---EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG 468

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +      DSG Y C A +  G      K+          PRF   ++      +G
Sbjct: 469  SCALILDSLTGVDSGQYMCFAASAAGNCSTLGKI-----LVQVPPRFVNKVR-ASPFVEG 522

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEY 3222
            + A F CT+     P  +I WY +G  +    + +T+S+   G +VL I      D G Y
Sbjct: 523  EDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 580

Query: 3223 VCRAYNKYG 3231
             C   N+ G
Sbjct: 581  ECELVNRLG 589



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 5/115 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            VQ  P F   +++    VEG+       +E    P  +I W+K+G  LTTG + ++  + 
Sbjct: 504  VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEP 560

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
              GL+ L I +   +D G+Y C+  N LG A ++A ++I+       E  H + L
Sbjct: 561  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL 615



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 10/146 (6%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FGF 1234
            P FV  +   P V EG++    C +E  G P  ++ W+ +G  +T G++F+T  +   G 
Sbjct: 508  PRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 564

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQLLED 1293
            + L I  A+  D G Y    VN LGSA  SA +R+             EQ +  +++ E 
Sbjct: 565  LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQ 624

Query: 1294 ---AARRTKQVREDI-TVMQAPQFSR 1315
                 ++T  + E I TV+++P+  R
Sbjct: 625  ETKVPKKTVIIEETITTVVKSPRGQR 650



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 36/138 (26%), Positives = 65/138 (47%), Gaps = 6/138 (4%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD- 1498
            V + PRFV + ++    +EG+   F C +E      ++  W+K+G  +T G++F+ + + 
Sbjct: 504  VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 560

Query: 1499 -FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDIVRSTQNEAGLEQIQ 1556
              G + L I     ED G+Y C  VN +G+   S  L  +S           E  +  ++
Sbjct: 561  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVE 620

Query: 1557 VLEDRSKYHRTDMVDEVT 1574
            V E  +K  +  ++ E T
Sbjct: 621  VTEQETKVPKKTVIIEET 638



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 40/141 (28%), Positives = 67/141 (47%), Gaps = 6/141 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V   P+F   +     VEG +    C ++  G    ++ W+ +G  + TG++F+   E
Sbjct: 502  ILVQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSE 559

Query: 1365 --FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL-EKI 1421
                 + L + +   ED G+Y C+  N+LG A  S  LR+ +      E  H   L   +
Sbjct: 560  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAV 619

Query: 1422 QYLE-DTSRYKKTDIIDESVT 1441
            +  E +T   KKT II+E++T
Sbjct: 620  EVTEQETKVPKKTVIIEETIT 640



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 37/136 (27%), Positives = 64/136 (47%), Gaps = 8/136 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND--FGF 3614
            PP F          E   A F C +       +R  W+ +G  L TG++ +T+++   G 
Sbjct: 507  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 564

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
            ++L I    + D GLY C+  NR G A  S +L++   Q  +L+ Q   H +    +++ 
Sbjct: 565  LVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLVAAVEV 621

Query: 3675 LE-ETLHKREEITIED 3689
             E ET   ++ + IE+
Sbjct: 622  TEQETKVPKKTVIIEE 637



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--H 4460
            G +    PP F  K++     E E A+F    +G P P I+WY++   +     FQ    
Sbjct: 500  GKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 559

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              S   +L+IR    ED  ++     NR G+A+ SA L ++    Q +
Sbjct: 560  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQ 607



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/98 (28%), Positives = 52/98 (53%), Gaps = 5/98 (5%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FG 3338
            PP+F+ +++  +  VEG+ A F   +     P ++  W+ +G  L  G++++T  +   G
Sbjct: 507  PPRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 563

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
            +++L I    +E+ G YEC   N+LG     A L+  S
Sbjct: 564  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 601



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND--FG 3751
            PPRF  +++ +  V EG    F C +E  G P  +I W+ +G    TG++  TL++   G
Sbjct: 507  PPRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 563

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + L I      D G Y C   N+ GSA  +A++
Sbjct: 564  LLVLVIRAASKEDLGLYECELVNRLGSARASAEL 597



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 8/137 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FG 2298
            PPRFV ++R +  V EG+ A F C +E    P +R  +Y +G  L +  +F    +   G
Sbjct: 507  PPRFVNKVRASPFV-EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 563

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL---EKIRE 2355
             + L I+    ED G Y  + +N LG   ++  + + +      E    E L    ++ E
Sbjct: 564  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTE 623

Query: 2356 LESAEPFKRPEIPEPVT 2372
             E+  P K   I E +T
Sbjct: 624  QETKVPKKTVIIEETIT 640



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 5/137 (3%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--R 690
           V  PP+F+  +++   +EG    F   IE  G P  +I W K+G  +   ++F ++   R
Sbjct: 504 VQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPR 561

Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQHPETLQYIQQ 749
            G + L + + + +D G Y C  V+  G A   A L + +P    +      + +  ++ 
Sbjct: 562 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEV 621

Query: 750 LEDYSKYQHQESIEEQT 766
            E  +K   +  I E+T
Sbjct: 622 TEQETKVPKKTVIIEET 638



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 12/163 (7%)

Query: 1701 SAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            S   +++ Q P  F   ++     E + A F   +   G P  ++ W ++G  +   N+ 
Sbjct: 497  STLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKF 554

Query: 1760 TTMHD--FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH-ES 1816
             T+ +   G + L ++  + ED G Y C  +N LG A  S+ L +QS      E  H E 
Sbjct: 555  QTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQ 614

Query: 1817 ALQKIQQLEDSSRYQRR----EDVEVAVNQAPRFITQLNGPTK 1855
             +  ++  E  ++  ++    E+    V ++PR   Q   P+K
Sbjct: 615  LVAAVEVTEQETKVPKKTVIIEETITTVVKSPR--GQRRSPSK 655



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSG 3491
            EGE+A F   +     P ++  WY +G  L  G++F+T  +   G ++L I     ED G
Sbjct: 521  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 578

Query: 3492 EYLCRAYNNYGEAVTTASMKVQ 3513
             Y C   N  G A  +A +++Q
Sbjct: 579  LYECELVNRLGSARASAELRIQ 600



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ +   PRF+  ++ +   VEG+ A F   +E        + WY +G  +T+ N+ QT 
Sbjct: 501  KILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAP--YPQIRWYKDGALLTTGNKFQTL 557

Query: 1096 HD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             +   G + L I +   ED G+Y     N  G A+ SA + +++         HR
Sbjct: 558  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 612



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/92 (28%), Positives = 43/92 (46%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F    + + F +G +A+F   + G P P + W +  A L   NK+      ++G + 
Sbjct: 507 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 566

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L+I+     D G Y C   N+ G A  S  ++
Sbjct: 567 LVIRAASKEDLGLYECELVNRLGSARASAELR 598



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSG 2180
            EG+ A F C +E    P+  I W+ +G  +  G++++T  +   G + L I     ED G
Sbjct: 521  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 578

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
             Y C+  N+LG A  +  L++
Sbjct: 579  LYECELVNRLGSARASAELRI 599



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-F 691
           V+ PP F   L   TA  G  +    R+   G P   I W K+G++++       I    
Sbjct: 410 VWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPD 467

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
           G  +L + SL   DSG+Y C A SA G   T  K ++ V PR
Sbjct: 468 GSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPR 509



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN--FGY 827
           P+F+  ++      EG +A F   +     P +R  WYKDG  +T  ++  ++     G 
Sbjct: 508 PRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 564

Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           + L I     ED G Y    VN+LG A ++A +R+
Sbjct: 565 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 599



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 4/124 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYV 2035
            P+F   ++ +   EG       T+     P +R  WY +G  +  G++F+T  +   G +
Sbjct: 508  PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLL 565

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L I  A  ED G Y C+  N +G A  ++ +++ +      +    ++L    E+ + E
Sbjct: 566  VLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQE 625

Query: 2096 RPKP 2099
               P
Sbjct: 626  TKVP 629



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFV 3887
            PP F  ++   T E  E V+  CRV     PK  I WY++GK +     +  + D  G  
Sbjct: 413  PPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 470

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +L +  +   DSG+Y+C A +  G   T   I  +  P  +
Sbjct: 471  ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFV 511



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP FE+   +     G   K   ++ G P PV+SW  K    V+ + + +   +  G  +
Sbjct: 413 PPDFEEELADCTAELGETVKLACRVTGTPKPVISW-YKDGKAVQVDPHHILIEDPDGSCA 471

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L++  +   D G+Y C A +  G
Sbjct: 472 LILDSLTGVDSGQYMCFAASAAG 494



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EG++  F C +E +  P  +I W+ +   L +G ++++  +     + L I    +ED G
Sbjct: 521  EGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 578

Query: 2845 IYTCKATNSKGSATTSGSLR 2864
            +Y C+  N  GSA  S  LR
Sbjct: 579  LYECELVNRLGSARASAELR 598



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG+ A +   +     P +R  WY +G  L  G++F+T  +   G + L I +    D G
Sbjct: 521  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 578

Query: 2580 LYMCKAINRAG 2590
            LY C+ +NR G
Sbjct: 579  LYECELVNRLG 589



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 9/129 (6%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAG 980
            EG  A F   +E  G    ++ W KDG  +   ++  T      G + L I++ +  D G
Sbjct: 521  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 578

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGL-EKIQYLEDASRYSKRT---EEE 1036
             Y C   N +G A  SA L I +      E  H   L   ++  E  ++  K+T   EE 
Sbjct: 579  LYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEET 638

Query: 1037 V-KITQKPR 1044
            +  + + PR
Sbjct: 639  ITTVVKSPR 647



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGF 3752
            PP F  E+ D      G  V   CRV   G P   I W+ +G+          + D  G 
Sbjct: 413  PPDFEEELAD-CTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGS 469

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             AL +D +   D+G+Y C A +  G+ +T  KI
Sbjct: 470  CALILDSLTGVDSGQYMCFAASAAGNCSTLGKI 502



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP FV+   A    EGE A+F C + G P P++ W  +G  +  G++++
Sbjct: 507  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 555



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            Q  +A+ K   +++    Q+R  + + V + P F  +L   T    G++    CR+   P
Sbjct: 385  QARTAIIKSSWVKEICGIQQR--LALPVWRPPDFEEELADCTA-ELGETVKLACRVTGTP 441

Query: 1873 DPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             P   + WY +GK +Q   H     +  G  AL + ++ G DSG+Y C A +  G   + 
Sbjct: 442  KPV--ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTL 499

Query: 1932 IRLNVQ 1937
             ++ VQ
Sbjct: 500  GKILVQ 505



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP   ++  +   + G   +   +++G P+P ++W+K+G+ +     H +I   + +   
Sbjct: 413 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 472

Query: 325 VRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESP 358
           + ++    DSG Y   A +  G   T G + V+ P
Sbjct: 473 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 507



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP F       T E GE  +  CRVTG PKP + W  +G  +
Sbjct: 413  PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAV 454



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFGYVA 2036
            P F + + +     G  V L   +T    P   + WY +G+ VQ   H        G  A
Sbjct: 414  PDFEEELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCA 471

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +      D+G YMC A +A G   T   + V
Sbjct: 472  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 504



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P   PP F  EL   T    G+T    C+V     P   I +Y +GKA+Q      +  D
Sbjct: 409  PVWRPPDFEEELADCTAEL-GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIED 465

Query: 2297 -FGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              G  +L +      D+G+Y   A +A G+C++
Sbjct: 466  PDGSCALILDSLTGVDSGQYMCFAASAAGNCST 498



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG-HR 1358
            Q R  + V + P F   L +     G  V L CR+   G     + W+ +GK ++   H 
Sbjct: 403  QQRLALPVWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHH 460

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                      AL L S+   DSG Y C A +  G   T
Sbjct: 461  ILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCST 498



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 943  VEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+ V+     I      G  AL + S+T  D+G Y C A +A G  +T   + +
Sbjct: 445  ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 504


>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
          Length = 2584

 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 8/194 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP+  E L D     G+ ++ +C++ G P P + WYK  K ++   +  +    D     
Sbjct: 629  PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688

Query: 4682 ISEAFPE-DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            I ++    D G Y C A ++AG  +   K+ V  P +  N    +P       EG+ AQF
Sbjct: 689  ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPF-----VEGEDAQF 743

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA--VLLIGNTYEEDTGTFTCRATTA 4798
               I     P I+W ++GAL+     FQ + E  +   VL+I    +ED G + C     
Sbjct: 744  TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 803

Query: 4799 AGQVETSAKLVVKS 4812
             G    SA+L ++S
Sbjct: 804  LGSARASAELRIQS 817



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGT-KPIDVYWLKNGKKVQPDIRNKILEE-DGTYT 4570
            PP F     +     G+ V+L  +VTGT KP+ + W K+GK VQ D  + ++E+ DG+  
Sbjct: 629  PPDFEEELADCTAELGETVKLACRVTGTPKPV-ISWYKDGKAVQVDPHHILIEDPDGSCA 687

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L++      DSG+Y C A ++AG      + +V +P                P  +  ++
Sbjct: 688  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP----------------PRFVNKVR 731

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ--MSRTADEYTLRISEAFPE 4688
                 EG+  +F+C I G P P ++WYK   L+     FQ      +    L I  A  E
Sbjct: 732  ASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKE 791

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            D G Y+C   N  G    +A+L++  P
Sbjct: 792  DLGLYECELVNRLGSARASAELRIQSP 818



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F +   D     G+  +  CRVTG P P ++W+ + + ++ D +H ++ +  G+ AL+
Sbjct: 630 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 689

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           + ++T  DSG   C A + +G  +   ++ V      V P+FV +       EGE     
Sbjct: 690 LDSLTGVDSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFT 744

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVA 569
               G P P+I W KDG  +    + +  ++   G   L I  A   D   Y+C   N  
Sbjct: 745 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 804

Query: 570 GSTATRARL 578
           GS    A L
Sbjct: 805 GSARASAEL 813



 Score = 69.7 bits (163), Expect = 2e-10
 Identities = 42/143 (29%), Positives = 77/143 (53%), Gaps = 8/143 (5%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V   PRF+ ++   +   EG+ A + C IE  P P +R  WY +G +L +G++++T 
Sbjct: 717  KILVQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTL 773

Query: 1897 ND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
            ++   G   L I     ED G Y C+ +N LG A +S  L +QS    +  +Q +   E+
Sbjct: 774  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHREQ 830

Query: 1955 IQYLEDDSRYKRAVQDDSFVVEK 1977
            +    +D+  +RA Q+ + V+++
Sbjct: 831  LVAAVEDTTLERADQEVTSVLKR 853



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 13/201 (6%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQIHTFSTKSI 4467
            +PP F +++  C     E  +      G P P+I WY++   ++  P    I        
Sbjct: 628  RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 687

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LI+  +   DS  +   A +  G       ++V+          VPP F    +      
Sbjct: 688  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----------VPPRFVNKVRASPFVE 737

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE--DGTYTLLILEAYPQDSGKYE 4585
            G+  +    + G     + W K+G  +    + + L E   G   L+I  A  +D G YE
Sbjct: 738  GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 797

Query: 4586 CVAINSAGEARCDAECVVSLP 4606
            C  +N  G AR  AE  +  P
Sbjct: 798  CELVNRLGSARASAELRIQSP 818



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 7/136 (5%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--TT 322
           PP+   K R S   EG DAQF   + G P P++ W+K+G  L   NK + ++        
Sbjct: 723 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 782

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP-TESYVQDQRSQYIT----DTQQR 377
           L +R   K D G Y     N  G    S  L ++SP  ++  Q  R Q +      T +R
Sbjct: 783 LVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLER 842

Query: 378 ETEERIEISEKALAPQ 393
             +E   + ++ L P+
Sbjct: 843 ADQEVTSVLKRLLGPK 858



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 57/233 (24%), Positives = 90/233 (38%), Gaps = 14/233 (6%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS-HRIRTVYAFG 3104
            RPP+F    +++ D +       + +   TG    VI W+ +GK ++   H I      G
Sbjct: 628  RPPDFE---EELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG 684

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +      DSG Y C A +  G      K+          PRF   ++      +G
Sbjct: 685  SCALILDSLTGVDSGQYMCFAASAAGNCSTLGKI-----LVQVPPRFVNKVR-ASPFVEG 738

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEY 3222
            + A F CT+     P  +I WY +G  +    + +T+S+   G +VL I      D G Y
Sbjct: 739  EDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 796

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPS 3275
             C   N+ G     A +          E    + L    E  +L+ A Q+  S
Sbjct: 797  ECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTS 849



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 5/113 (4%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD- 3883
            +V  PP+F+ ++++    E E  +F C +E    P++R  WY++G LL +G++++T+ + 
Sbjct: 719  LVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 776

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
              G + L I     ED G Y C  VN  G     A +  +  P +  Q Q  R
Sbjct: 777  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS-PMLQAQEQCHR 828



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP  +   ++ +   GG A+FE  + G+P P V+W +    LV+  + S +    T   S
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTT--YS 1029

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAIC 157
            L+++ +   D G YTC A+N  G+ +C
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLC 1056



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 28/91 (30%), Positives = 48/91 (52%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PP +     + + Q G  AQF+  + G+P+P VTW+K+  +L++S +          +L 
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            +R+    D+G YT LA+N  G ++    L V
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 5/115 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            VQ  P F   +++    VEG+       +E    P  +I W+K+G  LTTG + ++  + 
Sbjct: 720  VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEP 776

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSL 2750
              GL+ L I +   +D G+Y C+  N LG A ++A ++I+       E  H + L
Sbjct: 777  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL 831



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 38/138 (27%), Positives = 66/138 (47%), Gaps = 10/138 (7%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD- 1498
            V + PRFV + ++    +EG+   F C +E      ++  W+K+G  +T G++F+ + + 
Sbjct: 720  VQVPPRFVNKVRA-SPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEP 776

Query: 1499 -FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
              G + L I     ED G+Y C  VN +G+   S  L  +S    +   Q +   EQ+  
Sbjct: 777  RSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHREQLVA 833

Query: 1558 LEDRSKYHRTDMVDEVTT 1575
              + +   R D   EVT+
Sbjct: 834  AVEDTTLERAD--QEVTS 849



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 2/111 (1%)

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751
            E T +   + A D    + P   + ++D++      A FEA  I  GDP+  V W ++ V
Sbjct: 954  ETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKDSV 1011

Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             +  S RL+   +    +L +++V  +D+G YTC A N  G+ +  + L V
Sbjct: 1012 QLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 25/93 (26%), Positives = 47/93 (50%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            ++PP     ++  +      A+FE   +G+P P + WY+++  + +S         T   
Sbjct: 970  ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 1029

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
            L++R V  +D+ V+  +A+N GG   C A L+V
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 26/91 (28%), Positives = 46/91 (50%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PPS  +T ++V   +G   + +  + G     V W K+  ++    R    +E  TY+L+
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            +     +D+G Y C+A N+ G+  C AE +V
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 54.8 bits (126), Expect = 7e-06
 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 1/125 (0%)

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
            T   + D  S  + +T QR    +   +  A  P      +D     G   +F+  + G 
Sbjct: 940  TGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGD 999

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
            P P VTW+ +  Q+ D         E   ++L++ +V   D+GV TC+A+N  G+   + 
Sbjct: 1000 PQPSVTWYKDSVQLVDS-TRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKA 1058

Query: 479  RLNVI 483
             L V+
Sbjct: 1059 ELLVL 1063



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--H 4460
            G +    PP F  K++     E E A+F    +G P P I+WY++   +     FQ    
Sbjct: 716  GKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 775

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
              S   +L+IR    ED  ++     NR G+A+ SA L ++    Q +
Sbjct: 776  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQ 823



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 5/95 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FGF 1234
            P FV  +   P V EG++    C +E  G P  ++ W+ +G  +T G++F+T  +   G 
Sbjct: 724  PRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 780

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            + L I  A+  D G Y    VN LGSA  SA +R+
Sbjct: 781  LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 36/134 (26%), Positives = 67/134 (50%), Gaps = 11/134 (8%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FG 3338
            PP+F+ +++  +  VEG+ A F   +     P ++  W+ +G  L  G++++T  +   G
Sbjct: 723  PPRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 779

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398
            +++L I    +E+ G YEC   N+LG     A L+  S    +L +Q     E   + + 
Sbjct: 780  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSP---MLQAQEQCHRE---QLVA 833

Query: 3399 TLEDSMVRRKDTSV 3412
             +ED+ + R D  V
Sbjct: 834  AVEDTTLERADQEV 847



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 5/94 (5%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND--FG 3751
            PPRF  +++ +  V EG    F C +E  G P  +I W+ +G    TG++  TL++   G
Sbjct: 723  PPRFVNKVRASPFV-EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 779

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             + L I      D G Y C   N+ GSA  +A++
Sbjct: 780  LLVLVIRAASKEDLGLYECELVNRLGSARASAEL 813



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            ++I+  T++ P     ++D+ + Q G  A FEA +    DP   V WYKD   +  S+R+
Sbjct: 963  QAIDTHTARPPSMQVTIEDV-QAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRL 1019

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +        SL + H+ ++DAG YT  A N  G+ +  A + V
Sbjct: 1020 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 28/95 (29%), Positives = 42/95 (44%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP +   ++D     G   +F   I G P P+V WYK    +  S      +    Y+L 
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLV 1031

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            +     +D G Y C+A N+ G+V   A+L V   D
Sbjct: 1032 LRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGD 1066



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            + + P  +  I+D +  + GG A FEA +E  GD    V W KD   +  S+R++     
Sbjct: 969  TARPPSMQVTIED-VQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEG 1025

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
               +L ++ V   DAG YTC A N  GQ    A L ++
Sbjct: 1026 TTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 9/130 (6%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND--FGF 3614
            PP F          E   A F C +       +R  W+ +G  L TG++ +T+++   G 
Sbjct: 723  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 780

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
            ++L I    + D GLY C+  NR G A  S +L++   Q  +L+ Q   H +    +++ 
Sbjct: 781  LVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLVAAVE- 836

Query: 3675 LEETLHKREE 3684
             + TL + ++
Sbjct: 837  -DTTLERADQ 845



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 13/179 (7%)

Query: 1701 SAQDEVITQAPV-FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL 1759
            S   +++ Q P  F   ++     E + A F   +   G P  ++ W ++G  +   N+ 
Sbjct: 713  STLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKF 770

Query: 1760 TTMHD--FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESA 1817
             T+ +   G + L ++  + ED G Y C  +N LG A  S+ L +QS      E  H   
Sbjct: 771  QTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHRE- 829

Query: 1818 LQKIQQLEDSSRYQRREDVEVAVN-----QAPRFIT-QLNGPTKLSEGQSAHYECRIEP 1870
             Q +  +ED++  +  ++V   +      +AP   T  L GP     G  A  E   +P
Sbjct: 830  -QLVAAVEDTTLERADQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQP 887



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%)

Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448
            Q G TA F+   I  GDP   V W+++   + DS+R+++  +    S+ + HV  +D GV
Sbjct: 985  QTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGV 1042

Query: 2449 YMCRASNLLGE 2459
            Y C A N  G+
Sbjct: 1043 YTCLAQNTGGQ 1053



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 8/127 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V   P+F   +     VEG +    C ++  G    ++ W+ +G  + TG++F+   E
Sbjct: 718  ILVQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSE 775

Query: 1365 --FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK-I 1421
                 + L + +   ED G+Y C+  N+LG A  S  LR+   +  +L++Q     E+ +
Sbjct: 776  PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI---QSPMLQAQEQCHREQLV 832

Query: 1422 QYLEDTS 1428
              +EDT+
Sbjct: 833  AAVEDTT 839



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRL--QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF- 1365
            +AP F R L +   V G +V L C++  QP    T    W  +G P+++  R   +    
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQAT----WSKDGAPLESSSRVLISATLK 2132

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
            ++  L +L V  ED GVYTC  +N LG   T+  LR
Sbjct: 2133 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 26/104 (25%), Positives = 39/104 (37%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P        +  + G      A   G P P +TW KD V ++ +  L    +G   +L +
Sbjct: 973  PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVL 1032

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLH 594
                + DA  Y C AQN  G    +A L           +K+ H
Sbjct: 1033 RHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQSH 1076



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 6/107 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT-SIFNFGYV 828
            P F+R L D   +  G++     Q++  + P  +  W KDG P+ +SSR+  S     + 
Sbjct: 2079 PTFLRELSD-ETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR--STVTADLG 873
             L I+ + AED G YT    N LG   +T  +R A R  S+   D+G
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIG 2182



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD--FGFVILEISPTYPEDSG 3491
            EGE+A F   +     P ++  WY +G  L  G++F+T  +   G ++L I     ED G
Sbjct: 737  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 3492 EYLCRAYNNYGEAVTTASMKVQ 3513
             Y C   N  G A  +A +++Q
Sbjct: 795  LYECELVNRLGSARASAELRIQ 816



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746
            I+     PP   V I+D +    GG   F+  +E  GDP   + W+ +       +R+  
Sbjct: 965  IDTHTARPPSMQVTIED-VQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQ 1021

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
              +    +L + ++ ++DAG YTC A N  G     A++
Sbjct: 1022 QQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1036 EVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            ++ +   PRF+  ++ +   VEG+ A F   +E        + WY +G  +T+ N+ QT 
Sbjct: 717  KILVQVPPRFVNKVRAS-PFVEGEDAQFTCTIEGAP--YPQIRWYKDGALLTTGNKFQTL 773

Query: 1096 HD--FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             +   G + L I +   ED G+Y     N  G A+ SA + +++         HR
Sbjct: 774  SEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 828



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP   V ++ V A  GG   FE  IE  GDP   + W K+   +  S+R +        S
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 1029

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +  +  +D+G YTC A +  G    KA L V
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 22/84 (26%), Positives = 40/84 (47%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE 4786
            + D+    G  AQF+  I    +P++ W ++   + ++       EG    L++ +   +
Sbjct: 979  IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASK 1038

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            D G +TC A    GQV   A+L+V
Sbjct: 1039 DAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 5/96 (5%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FG 2298
            PPRFV ++R +  V EG+ A F C +E    P +R  +Y +G  L +  +F    +   G
Sbjct: 723  PPRFVNKVRASPFV-EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSG 779

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             + L I+    ED G Y  + +N LG   ++  + +
Sbjct: 780  LLVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/92 (28%), Positives = 43/92 (46%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F    + + F +G +A+F   + G P P + W +  A L   NK+      ++G + 
Sbjct: 723 PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLV 782

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L+I+     D G Y C   N+ G A  S  ++
Sbjct: 783 LVIRAASKEDLGLYECELVNRLGSARASAELR 814



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSG 2180
            EG+ A F C +E    P+  I W+ +G  +  G++++T  +   G + L I     ED G
Sbjct: 737  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
             Y C+  N+LG A  +  L++
Sbjct: 795  LYECELVNRLGSARASAELRI 815



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            + ++  + G    FE  +E   DP   + W+ ++  L   TR     + +  SL + H  
Sbjct: 979  IEDVQAQTGGTAQFEAIIEG--DPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVA 1036

Query: 2840 EEDSGIYTCKATNSKGSATTSGSLRCTGDKN 2870
             +D+G+YTC A N+ G       L   G  N
Sbjct: 1037 SKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--R 690
           V  PP+F+  +++   +EG    F   IE  G P  +I W K+G  +   ++F ++   R
Sbjct: 720 VQVPPRFVNKVRASPFVEGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPR 777

Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQL 750
            G + L + + + +D G Y C  V+  G A   A L +       +   H E  Q +  +
Sbjct: 778 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHRE--QLVAAV 835

Query: 751 ED 752
           ED
Sbjct: 836 ED 837



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 1/107 (0%)

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
            K+ +  P  +  L D+ V  GQ++  +C++  +P     W K    ++ S    +S T  
Sbjct: 2073 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 2132

Query: 4677 EY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
             +  L I     ED G Y C   N+ G VT    L+  +   +   P
Sbjct: 2133 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCP 2179



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/56 (42%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 945  WLKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            W KDG P+E+SSR+        +  LTI  V   D G YTC   NA+G  TT+  L
Sbjct: 2112 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 2167



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-F 691
           V+ PP F   L   TA  G  +    R+   G P   I W K+G++++       I    
Sbjct: 626 VWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPD 683

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAET--KAVLHVTPR 731
           G  +L + SL   DSG+Y C A SA G   T  K ++ V PR
Sbjct: 684 GSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPR 725



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 4/92 (4%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF- 1899
            ++AP F+ +L+  T +  GQS    C++     P  +  W  +G  L+S  R   S    
Sbjct: 2076 DRAPTFLRELSDETVVL-GQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLK 2132

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             F  L IL V  ED G YTC   N LG   ++
Sbjct: 2133 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTT 2164



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 3/90 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDF-SYVSLD 2834
            F+  L++     G ++   C V  S  P  +  W  +  PL S +R   +    ++  L 
Sbjct: 2081 FLRELSDETVVLGQSVTLACQV--SAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 2138

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            I     ED G+YTC  +N+ G+ TT+G LR
Sbjct: 2139 ILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN--FGY 827
           P+F+  ++      EG +A F   +     P +R  WYKDG  +T  ++  ++     G 
Sbjct: 724 PRFVNKVR-ASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGL 780

Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           + L I     ED G Y    VN+LG A ++A +R+
Sbjct: 781 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 8/101 (7%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTF-D 2696
            +AP F   L S + +V GQ V L  QV  +  P  +  W K+G  L + +R  + +T  +
Sbjct: 2077 RAPTFLREL-SDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKN 2133

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            F L+T+ +  +  +D G+YTC  +N LG   +T  ++  +R
Sbjct: 2134 FQLLTILV--VVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 9/128 (7%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAG 980
            EG  A F   +E  G    ++ W KDG  +   ++  T      G + L I++ +  D G
Sbjct: 737  EGEDAQFTCTIE--GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKIT 1040
             Y C   N +G A  SA L I +      E  H   L  +  +ED +   +R ++EV   
Sbjct: 795  LYECELVNRLGSARASAELRIQSPMLQAQEQCHREQL--VAAVEDTT--LERADQEVTSV 850

Query: 1041 QKPRFLGP 1048
             K R LGP
Sbjct: 851  LK-RLLGP 857



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
            G +A FEA +E   D   +V WY +  Q+  + R+    +    +L +  V ++D+GVYT
Sbjct: 987  GGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 1044

Query: 1118 VVARNAAGEAQLSASMTV 1135
             +A+N  G+    A + V
Sbjct: 1045 CLAQNTGGQVLCKAELLV 1062



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GY 1767
            +AP F   + D  V   Q+     ++     P  +  W ++G P+E+S+R+        +
Sbjct: 2077 RAPTFLRELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNF 2134

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
              L +  V  ED G YTC   N LG   T+  L
Sbjct: 2135 QLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 2167



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 24/81 (29%), Positives = 46/81 (56%), Gaps = 6/81 (7%)

Query: 4639 AIEFSCKIVGKPLPTVQWYK-----GDKLIKP-SKYFQMSRTADEYTLRISEAFPEDEGD 4692
            +I F  K+ G+P+PTV W +     G   I P +  + ++ +A +++L + +   + +G 
Sbjct: 2    SITFFVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGT 61

Query: 4693 YKCVAYNSAGRVTVAAKLKVT 4713
            Y C+A N+AG+   +A L V+
Sbjct: 62   YTCIASNAAGQALCSASLHVS 82



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYV 2035
            P+F   ++ +   EG       T+     P +R  WY +G  +  G++F+T  +   G +
Sbjct: 724  PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLL 781

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
             L I  A  ED G Y C+  N +G A  ++ +++ +
Sbjct: 782  VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 817



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 2/101 (1%)

Query: 3551 EAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN 3610
            +  +  PP    T  D+      +A FE   I   D    V W+ +   L+  +R+    
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            +     L +  V  +DAG+YTC A N  G+     +L V G
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLG 1064



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 9/129 (6%)

Query: 2621 LKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFK 2680
            ++E          +DT   + P     ++       G   + EA +E   DP   + W+K
Sbjct: 952  VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQF-EAIIEG--DPQPSVTWYK 1008

Query: 2681 NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL 2740
            + V L    RL    +    +L +  + + D+G+YTC A N  G+ +  A + +      
Sbjct: 1009 DSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV------ 1062

Query: 2741 LGESLHPDS 2749
            LG    PDS
Sbjct: 1063 LGGDNEPDS 1071



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 8/91 (8%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV---HTLNDFG 3751
            P F  E+ D   V  G  V   C+V     P  +  W  +G P  + SRV    TL +F 
Sbjct: 2079 PTFLRELSDET-VVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
             + + +  + A D G YTC  +N  G+ TTT
Sbjct: 2136 LLTILV--VVAEDLGVYTCSVSNALGTVTTT 2164



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 6/77 (7%)

Query: 4740 FKTQITSKIKPTIQWLREGA------LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            F  ++  +  PT+ WLRE A      + P+TP + +        L++ +   +  GT+TC
Sbjct: 5    FFVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 64

Query: 4794 RATTAAGQVETSAKLVV 4810
             A+ AAGQ   SA L V
Sbjct: 65   IASNAAGQALCSASLHV 81



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFV 3887
            PP F  ++   T E  E V+  CRV     PK  I WY++GK +     +  + D  G  
Sbjct: 629  PPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 686

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +L +  +   DSG+Y+C A +  G   T   I  +  P  +
Sbjct: 687  ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFV 727



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP FE+   +     G   K   ++ G P PV+SW  K    V+ + + +   +  G  +
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISW-YKDGKAVQVDPHHILIEDPDGSCA 687

Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153
           L++  +   D G+Y C A +  G
Sbjct: 688 LILDSLTGVDSGQYMCFAASAAG 710



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EG++  F C +E +  P  +I W+ +   L +G ++++  +     + L I    +ED G
Sbjct: 737  EGEDAQFTCTIEGAPYP--QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 2845 IYTCKATNSKGSATTSGSLR 2864
            +Y C+  N  GSA  S  LR
Sbjct: 795  LYECELVNRLGSARASAELR 814



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG+ A +   +     P +R  WY +G  L  G++F+T  +   G + L I +    D G
Sbjct: 737  EGEDAQFTCTIEGAPYPQIR--WYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLG 794

Query: 2580 LYMCKAINRAG 2590
            LY C+ +NR G
Sbjct: 795  LYECELVNRLG 805



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 2/113 (1%)

Query: 1557 VLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
            V E   + +    +D  T + P    ++++V+ + G  A FE   I   D    V WY +
Sbjct: 952  VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEA--IIEGDPQPSVTWYKD 1009

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            +  L   +R ++       +L +     +D+G YTC A N  G+ +     +V
Sbjct: 1010 SVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 1062



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 4/108 (3%)

Query: 468  RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
            R K G  +F  RL+ + K    AP F+   S   V  G+ V L  +    P  + TW KD
Sbjct: 2059 RKKPGLASF--RLSGL-KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKD 2115

Query: 528  GVPIIPNPELRIH-TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            G P+  +  + I  T      L I    A D   Y C+  N  G+  T
Sbjct: 2116 GAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTT 2163



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYVA 2036
            P F + + +  V  G  V L   ++    P  +  W  +G P++   R   +     +  
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
            L IL   AED G Y C  +NA+G   TT  ++
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 3139 ECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
            + +D    + P     I++++  + G +A FE  +    DP   + WY +   +  STR+
Sbjct: 963  QAIDTHTARPPSMQVTIEDVQA-QTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRL 1019

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
                +     L + +  + D+G Y C A N  G+   +A +   G
Sbjct: 1020 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLG 1064



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 8/78 (10%)

Query: 94  KLRGNPTPVVSWTRKKAPL------VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCT 147
           K+ G P P V W R++A         +   Y++  + Q    SL++  +G   +G YTC 
Sbjct: 8   KVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH--SLVLLDVGRQHQGTYTCI 65

Query: 148 ARNQYGEAICSVYIQPEG 165
           A N  G+A+CS  +   G
Sbjct: 66  ASNAAGQALCSASLHVSG 83



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGF 3752
            PP F  E+ D      G  V   CRV   G P   I W+ +G+          + D  G 
Sbjct: 629  PPDFEEELAD-CTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHHILIEDPDGS 685

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             AL +D +   D+G+Y C A +  G+ +T  KI
Sbjct: 686  CALILDSLTGVDSGQYMCFAASAAGNCSTLGKI 718



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYV 1502
            P F+ R  S E V+ GQ V   C++        +  W K+G P+    R         + 
Sbjct: 2079 PTFL-RELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGT 1527
             L I+ ++AED G+YTC   N +GT
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGT 2160



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 17/49 (34%), Positives = 28/49 (57%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP FV+   A    EGE A+F C + G P P++ W  +G  +  G++++
Sbjct: 723  PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 771



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 28/97 (28%), Positives = 40/97 (41%), Gaps = 3/97 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVS 3888
            P F+ ++   TV   + V   C+V  +  P  +  W ++G  L S  R      +  F  
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L IL V AED G Y C   N  G   T   +   + P
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERP 2173



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 1613 WYHNNKPLKSGSRFTETNNF-GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666
            W  +  PL+S SR   +     F  L I+  + ED G YTC   NALG   T+G+
Sbjct: 2112 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGV 2166



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            Q  +A+ K   +++    Q+R  + + V + P F  +L   T    G++    CR+   P
Sbjct: 601  QARTAIIKSSWVKEICGIQQR--LALPVWRPPDFEEELADCTA-ELGETVKLACRVTGTP 657

Query: 1873 DPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             P   + WY +GK +Q   H     +  G  AL + ++ G DSG+Y C A +  G   + 
Sbjct: 658  KPV--ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTL 715

Query: 1932 IRLNVQ 1937
             ++ VQ
Sbjct: 716  GKILVQ 721



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 2/104 (1%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            DT   +P  +     + Q   G     E  +E   DP   + WY +   L   +R     
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            +    +L L  V  +D+G+YTC A N  G+    + +     DN
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR-FTSIFRFGYIS 695
            P F+  L   T + G  +    ++     P  +  W K+G  +E+SSR   S     +  
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L +L +  +D G YTC   +A G   T  VL    R
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 7/85 (8%)

Query: 4536 KVTGTKPIDVYWLKNGKK-----VQPDIRNKILEEDGT-YTLLILEAYPQDSGKYECVAI 4589
            KV G     V+WL+   +     + PD     +      ++L++L+   Q  G Y C+A 
Sbjct: 8    KVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIAS 67

Query: 4590 NSAGEARCDAECVVS-LPATKDKPK 4613
            N+AG+A C A   VS LP  +++ K
Sbjct: 68   NAAGQALCSASLHVSGLPKVEEQEK 92



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 3/110 (2%)

Query: 3029 EDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG 3088
            E + R    Q  D  T RPP      +D V    G  A +EA  I  GD    + W+ + 
Sbjct: 954  ETTQRTYTYQAIDTHTARPPSMQVTIED-VQAQTGGTAQFEA--IIEGDPQPSVTWYKDS 1010

Query: 3089 KTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
              +  S R+          L +    + D+G Y+C A N  GQ     +L
Sbjct: 1011 VQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 3272 QTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRY 3331
            Q   T +A PP     I+DV +   G +A FEA  +   DP   V W+ +  +L    R 
Sbjct: 963  QAIDTHTARPPSMQVTIEDV-QAQTGGTAQFEA--IIEGDPQPSVTWYKDSVQLVDSTRL 1019

Query: 3332 RTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379
                +     L + +   +++G Y C+A N  G+   KA L     +N
Sbjct: 1020 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            D    +P   QV     +   G  A +EA +   GDP     WY + V+L   +R     
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +    +L +  V + DAG+Y C A N  G
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGG 1052



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 9/117 (7%)

Query: 2346 RPEGLEKI---RELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIP 2402
            RPEGLEK    R+      F+   +      + P F + L + + +  GQ+    C++  
Sbjct: 2048 RPEGLEKEGPPRKKPGLASFRLSGLKS--WDRAPTFLRELSD-ETVVLGQSVTLACQVS- 2103

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLG 2458
               P  +  W ++   +E SSR+  +     +  +TI  V  ED GVY C  SN LG
Sbjct: 2104 -AQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALG 2159



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP   ++  +   + G   +   +++G P+P ++W+K+G+ +     H +I   + +   
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688

Query: 325 VRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESP 358
           + ++    DSG Y   A +  G   T G + V+ P
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 723



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF-GFV 1235
            P F++ LS+   V  G+++ L C++     P  +  W  +G  +   SR         F 
Sbjct: 2079 PTFLRELSDETVVL-GQSVTLACQVS--AQPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             L I+   + D G YT    N LG+  T+ ++R  ER
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 2/88 (2%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTL 338
            G       Q+S  P  + TW K+G  L +S++  I  T  N   L +      D G YT 
Sbjct: 2093 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 2152

Query: 339  LAENPNGCIVTSGYL-AVESPTESYVQD 365
               N  G + T+G L   E P+ S   D
Sbjct: 2153 SVSNALGTVTTTGVLRKAERPSSSPCPD 2180



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 5/112 (4%)

Query: 411 FDCRVTGRPYPEVTWFINDRQ-----IRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           F  +V GRP P V W   + +     I  D     + + +  H+L++ +V     G  TC
Sbjct: 5   FFVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 64

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           +A N +G+      L+V    +V   + V+        +G    ++A+ + T
Sbjct: 65  IASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLET 116



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP F       T E GE  +  CRVTG PKP + W  +G  +
Sbjct: 629  PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAV 670



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP     I+    +     +FE  +E   DP+  + WY++   L    R     +    S
Sbjct: 972  PPSMQVTIEDVQAQTGGTAQFEAIIEG--DPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 1029

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            L + +V ++D+G Y C A N  G+   KA +
Sbjct: 1030 LVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 22/82 (26%), Positives = 31/82 (37%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F++   D  V  G+     C+V+ +P  + TW  +   +       I         L
Sbjct: 2078 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 2137

Query: 451  MITNVTLSDSGVVTCVARNKSG 472
             I  V   D GV TC   N  G
Sbjct: 2138 TILVVVAEDLGVYTCSVSNALG 2159



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +A +E  IE  P P+  V WY +   L    R     +    +L +  V  +D+G YT
Sbjct: 987  GGTAQFEAIIEGDPQPS--VTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 1044

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            C A N  GQ +    L V   ++   DS+ +S   K+
Sbjct: 1045 CLAQNTGGQVLCKAELLVLGGDN-EPDSEKQSHRRKL 1080



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 4/95 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-GYV 2167
            P FL  L+  E +  G      C+V     P     W  +G  + +  R   +     + 
Sbjct: 2079 PTFLRELSD-ETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
             L IL   AED G Y C  +N LG    T  L+ A
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKA 2170



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFGYVA 2036
            P F + + +     G  V L   +T    P   + WY +G+ VQ   H        G  A
Sbjct: 630  PDFEEELADCTAELGETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIEDPDGSCA 687

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L +      D+G YMC A +A G   T   + V
Sbjct: 688  LILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 720



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 2/100 (2%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            D    + P     + +++   G     E  ++  GD    V W+ +   +    R     
Sbjct: 966  DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQ 1023

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            E    +L L  V  +D+GVYTC A N  G+ +    L V+
Sbjct: 1024 EGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVL 1063



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 6/77 (7%)

Query: 4430 FEVEFDGEPLPLIKWYREN------FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            F V+ +G P+P + W RE       +   ++P + + + + +  L++  V  +    +  
Sbjct: 5    FFVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTC 64

Query: 4484 VAENRGGTAKCSANLVV 4500
            +A N  G A CSA+L V
Sbjct: 65   IASNAAGQALCSASLHV 81



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 3/107 (2%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            +++    + P   V + +++  + G  A FEA +    DP   V WY +   L   +R  
Sbjct: 964  AIDTHTARPPSMQVTIEDVQ-AQTGGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLS 1020

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
               +     L +     +D+G Y C A N  G+ +  A + V G  N
Sbjct: 1021 QQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 11/159 (6%)

Query: 3936 GMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRF---VTQIQSQTSLVEMETTK 3992
            G    E L  + + + + T++   T   + D    +PP     +  +Q+QT      T +
Sbjct: 937  GAGTGELLWDVHSHVVRETTQRTYTYQAI-DTHTARPPSMQVTIEDVQAQTG----GTAQ 991

Query: 3993 FECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATN 4052
            FE  +   GDP   V W+ +   L+   R +   +    ++    V  +D+G Y C A N
Sbjct: 992  FEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQN 1049

Query: 4053 LYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
              G    KA +   G      DS+   H + +    E++
Sbjct: 1050 TGGQVLCKAELLVLGGDN-EPDSEKQSHRRKLHSFYEVK 1087



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2919 AEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLVDVY 2977
            ++  +V GQ + L  QV  +  P  +  W  +G  LE  SR  +++    F  L ++ V 
Sbjct: 2086 SDETVVLGQSVTLACQVSAQ--PAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVV 2143

Query: 2978 ERDSGIYTCKAYNKRGEAFTSSTV 3001
              D G+YTC   N  G   T+  +
Sbjct: 2144 AEDLGVYTCSVSNALGTVTTTGVL 2167



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P   PP F  EL   T    G+T    C+V     P   I +Y +GKA+Q      +  D
Sbjct: 625  PVWRPPDFEEELADCTAEL-GETVKLACRVTGTPKPV--ISWYKDGKAVQVDPHHILIED 681

Query: 2297 -FGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              G  +L +      D+G+Y   A +A G+C++
Sbjct: 682  PDGSCALILDSLTGVDSGQYMCFAASAAGNCST 714



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A FE  +E   DP  ++ W+ +  ++    R     +    +L + +  ++D+G Y 
Sbjct: 987  GGTAQFEAIIE--GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 1044

Query: 2184 CKATNKLGEAVNTCTLKVAGHRN 2206
            C A N  G+ +    L V G  N
Sbjct: 1045 CLAQNTGGQVLCKAELLVLGGDN 1067



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 3/122 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P F    SD  +    S    C++      + +  W  +G PL + SRV        F +
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQL 2136

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V   D G+YTC  +N  G  T +  L+   R      P +   +  G   + K  
Sbjct: 2137 LTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPV 2196

Query: 3677 ET 3678
            E+
Sbjct: 2197 ES 2198



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 4/88 (4%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF-GYV 2300
            P F+ EL   T V  G++    CQV     P  +  +  +G  L+S++R  I+     + 
Sbjct: 2079 PTFLRELSDETVVL-GQSVTLACQVSA--QPAAQATWSKDGAPLESSSRVLISATLKNFQ 2135

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTS 2328
             L I   V ED G Y+    NALG  T+
Sbjct: 2136 LLTILVVVAEDLGVYTCSVSNALGTVTT 2163



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 1300 QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG-HR 1358
            Q R  + V + P F   L +     G  V L CR+   G     + W+ +GK ++   H 
Sbjct: 619  QQRLALPVWRPPDFEEELADCTAELGETVKLACRV--TGTPKPVISWYKDGKAVQVDPHH 676

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
                      AL L S+   DSG Y C A +  G   T
Sbjct: 677  ILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCST 714



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 943  VEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            + W KDG+ V+     I      G  AL + S+T  D+G Y C A +A G  +T   + +
Sbjct: 661  ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 720


>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
          Length = 1447

 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 89/378 (23%), Positives = 159/378 (42%), Gaps = 35/378 (9%)

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
            +P+IKW ++   +    D +    S  S+LI        + + +   +   G  +C A+L
Sbjct: 69   VPVIKWKKDGIHLALGMDERKQQLSNGSLLI-------QNILHSRHHKPDEGLYQCEASL 121

Query: 4499 -----VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++    +    G  P  F    ++V    G  V L  +V G     ++W KN + 
Sbjct: 122  GDSGSIISRTAKVAVAG--PLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQD 179

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P   +  +    +  L I    P D G Y C A N A  +R   E  V + +     +
Sbjct: 180  LTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPAS-SRTGNEAEVRILSDPGLHR 238

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK-PSKYFQMS 4672
             Q      P  ++         EG+     C + G P P+  W +G+++I+  SK + + 
Sbjct: 239  -QLYFLQRPSNVV-------AIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLL 290

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
              ++   L IS    +D G Y CV       ++ +A+L V  P    N P+     ++  
Sbjct: 291  GGSN---LLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPS-----NLYA 342

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
            YE    +F+  ++ K  PT+ W++ G ++  +  FQ++   N  +L      + D G + 
Sbjct: 343  YESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL---GVVKSDEGFYQ 399

Query: 4793 CRATTAAGQVETSAKLVV 4810
            C A   AG  +TSA+L+V
Sbjct: 400  CVAENEAGNAQTSAQLIV 417



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 88/338 (26%), Positives = 130/338 (38%), Gaps = 30/338 (8%)

Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
            ++T +  V GP++      F  + +    F  +    + E  GEP+P I W +    +  
Sbjct: 129  SRTAKVAVAGPLR------FLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTP 182

Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513
             P            L I ++   D  ++   A N    A        E +     G    
Sbjct: 183  IPGDSRVVVLPSGALQISRLQPGDIGIYRCSARN---PASSRTGNEAEVRILSDPGLHRQ 239

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
              F     NV    G+   L+  V+G  P    WL+  + +Q  +R+K     G   LLI
Sbjct: 240  LYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQ--LRSKKYSLLGGSNLLI 297

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
                  DSG Y CV           AE  V +P                P  +    +  
Sbjct: 298  SNVTDDDSGMYTCVVTYKNENISASAELTVLVP----------------PWFLNHPSNLY 341

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
              E   IEF C + GKP+PTV W K   ++ PS YFQ+   ++   LRI      DEG Y
Sbjct: 342  AYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSN---LRILGVVKSDEGFY 398

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
            +CVA N AG    +A+L V +P    +    +  RD+V
Sbjct: 399  QCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVV 436



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 66/203 (32%), Positives = 93/203 (45%), Gaps = 14/203 (6%)

Query: 378 ETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
           E E RI +S+  L  Q   + +  +V   EGK    +C V+G P P  TW   +  I+  
Sbjct: 225 EAEVRI-LSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLR 283

Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
                L+   G   L+I+NVT  DSG+ TCV   K+   +    L V+     V P F+ 
Sbjct: 284 SKKYSLL---GGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVL-----VPPWFLN 335

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
             S L   E   +       G P P + W K+G  +IP+   +I    G S L I     
Sbjct: 336 HPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVK 392

Query: 556 SDAAWYQCTAQNVAGSTATRARL 578
           SD  +YQC A+N AG+  T A+L
Sbjct: 393 SDEGFYQCVAENEAGNAQTSAQL 415



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 36/94 (38%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP     P N    E  D +F+  +SG P P V W KNG  +I S+  +I+   N   LR
Sbjct: 330 PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSN---LR 386

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           +    KSD G Y  +AEN  G   TS  L V  P
Sbjct: 387 ILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKP 420



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 6/117 (5%)

Query: 625 IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
           I    E  V  PP F+    ++ A E   I FE  +   G P   + W+KNG  +  S  
Sbjct: 319 ISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDVVIPSDY 376

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
           F  +   G  +L +L +   D G Y C A +  G A+T A L + P+  I  +S  P
Sbjct: 377 FQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL-IVPKPAIPSSSVLP 429



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 10/157 (6%)

Query: 4348 PDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTE----TTEIEHKAQTQERVVEG 4403
            P PS + + G+EV   + K+    + G   +   +T  +    T  + +K +      E 
Sbjct: 267  PPPSFTWLRGEEVIQLRSKKYSL-LGGSNLLISNVTDDDSGMYTCVVTYKNENISASAEL 325

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
             V    PP F         +E     FE    G+P+P + W +    +  S  FQI   S
Sbjct: 326  TVLV--PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGS 383

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
               IL    V   D   +  VAEN  G A+ SA L+V
Sbjct: 384  NLRIL---GVVKSDEGFYQCVAENEAGNAQTSAQLIV 417



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 46/189 (24%), Positives = 76/189 (40%), Gaps = 15/189 (7%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           A +F+    D     G     DC   + R  P + W  +   +    + +    +  N +
Sbjct: 39  ALRFLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDER--KQQLSNGS 96

Query: 450 LMITNVTLS-----DSGVVTCVAR-NKSGETAFQCRLNVIEKEQVVAP-KFVERFSTLNV 502
           L+I N+  S     D G+  C A    SG       ++   K  V  P +F+ +  ++  
Sbjct: 97  LLIQNILHSRHHKPDEGLYQCEASLGDSGSI-----ISRTAKVAVAGPLRFLSQTESVTA 151

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             G+ V+L    +G P P I WQK+   + P P         +  L I R +  D   Y+
Sbjct: 152 FMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYR 211

Query: 563 CTAQNVAGS 571
           C+A+N A S
Sbjct: 212 CSARNPASS 220



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 7/115 (6%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E  V  PP F+    +    ES  + FEC V  K  P   + W +NG ++     ++ V 
Sbjct: 324  ELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVP--TVNWMKNGDVVIPSDYFQIV- 380

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK--LPDIILQNQVPR 3935
              G  +L IL V   D G Y C A N+ G   T A +   K  +P   +    PR
Sbjct: 381  --GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPR 433



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 270 QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEIITTHNHTTLRVRNT 328
           Q+P N    EG DA  +  +SG P P  TW +  + + + S K+ ++   N   L + N 
Sbjct: 244 QRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSN---LLISNV 300

Query: 329 QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
              DSG YT +    N  I  S  L V  P
Sbjct: 301 TDDDSGMYTCVVTYKNENISASAELTVLVP 330



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/73 (36%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 411 FDCRVTGRPYPEVTWFIN-DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
           F+C V+G+P P V W  N D  I  DY   +     G   L I  V  SD G   CVA N
Sbjct: 350 FECTVSGKPVPTVNWMKNGDVVIPSDYFQIV-----GGSNLRILGVVKSDEGFYQCVAEN 404

Query: 470 KSGETAFQCRLNV 482
           ++G      +L V
Sbjct: 405 EAGNAQTSAQLIV 417



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 6/127 (4%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++TV+  P F     N+   E  ++  EC +   G     V W  NG  +     F+   
Sbjct: 324  ELTVLVPPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDVVIPSDYFQIVG 381

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQY 1423
              +   L +L V   D G Y C A N+ G A TS  L ++ K  +   S  PS    +  
Sbjct: 382  GSN---LRILGVVKSDEGFYQCVAENEAGNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVP 437

Query: 1424 LEDTSRY 1430
            +  +SR+
Sbjct: 438  VLVSSRF 444



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 5/93 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   PS+L   E+    FEC +         V W  NG  ++     + +      I
Sbjct: 330  PPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRI 387

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L   GV + D G Y C A N  G A  S +L V
Sbjct: 388  L---GVVKSDEGFYQCVAENEAGNAQTSAQLIV 417



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 5/88 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++H +N+   E  +I FEC V     PT  + W  N   +     ++     +   L I
Sbjct: 333  FLNHPSNLYAYESMDIEFECTVSGKPVPT--VNWMKNGDVVIPSDYFQIVGGSN---LRI 387

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                + D G Y C A N  G+A TS  L
Sbjct: 388  LGVVKSDEGFYQCVAENEAGNAQTSAQL 415



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 10/98 (10%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            +V + P F+  P ++    E   + FEC +  +PV   N    W KNG  V     F+ +
Sbjct: 326  TVLVPPWFLNHPSNLY-AYESMDIEFECTVSGKPVPTVN----WMKNGDVVIPSDYFQIV 380

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
               G   L I+ ++  D G Y C A N  G  + S +L
Sbjct: 381  ---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL 415



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 7/140 (5%)

Query: 1694 TSKYQRHSAQDEV-ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVP 1752
            T K +  SA  E+ +   P F     ++   E+    FE  +   G P   V W++NG  
Sbjct: 313  TYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDV 370

Query: 1753 IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
            +  S+    +   G   L +  V   D G Y C A NE G A TS+ L V  K ++   S
Sbjct: 371  VIPSDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIV-PKPAIPSSS 426

Query: 1813 QHESALQKIQQLEDSSRYQR 1832
               SA + +  +  SSR+ R
Sbjct: 427  VLPSAPRDVVPVLVSSRFVR 446



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 8/119 (6%)

Query: 1850 LNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL 1907
            LN P+ L   E     +EC +   P P   V W  NG V+     ++     G + L IL
Sbjct: 334  LNHPSNLYAYESMDIEFECTVSGKPVPT--VNWMKNGDVVIPSDYFQI---VGGSNLRIL 388

Query: 1908 TVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKR 1966
             V   D G Y C A N  G A +S +L +  K +I   S   SA   +  +   SR+ R
Sbjct: 389  GVVKSDEGFYQCVAENEAGNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVPVLVSSRFVR 446



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F     N    +  + +FE  + G P P V+W +    ++  +     Y +  G  +
Sbjct: 330 PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSD-----YFQIVGGSN 384

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L I  +   DEG Y C A N+ G A  S  +
Sbjct: 385 LRILGVVKSDEGFYQCVAENEAGNAQTSAQL 415



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 2367 IPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT 2426
            + +P   ++  F Q   N+  I EG+ A  +C +   G P     W R E++I+  S+  
Sbjct: 231  LSDPGLHRQLYFLQRPSNVVAI-EGKDAVLECCVS--GYPPPSFTWLRGEEVIQLRSK-- 285

Query: 2427 KTHDFGYVSMTISHVRDEDEGVYMC 2451
            K    G  ++ IS+V D+D G+Y C
Sbjct: 286  KYSLLGGSNLLISNVTDDDSGMYTC 310



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 7/103 (6%)

Query: 1167 YQIEEISKSKP--VFVQP--LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            Y+ E IS S    V V P  L++P  +   +++ +E      G P   V W  NG  V  
Sbjct: 314  YKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIP 373

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
               F+     G   L I+    +D G Y   A N  G+A TSA
Sbjct: 374  SDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSA 413



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 15/50 (30%), Positives = 26/50 (52%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            PP F++ P  +   E     F C V+G P P V W+ NG+ ++    +++
Sbjct: 330  PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQI 379



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P W +   +     E   +  E  V  K  P   + W  NG V+     F++    G   
Sbjct: 330  PPWFLNHPSNLYAYESMDIEFECTVSGKPVPT--VNWMKNGDVVIPSDYFQIV---GGSN 384

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            L ++ V + D G Y C A N+ G A TS+
Sbjct: 385  LRILGVVKSDEGFYQCVAENEAGNAQTSA 413



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 4/87 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W+K+G  V  S     F   G   L I  V   D G Y C A N  G A TSA L IV
Sbjct: 362  VNWMKNGDVVIPSDY---FQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL-IV 417

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRY 1029
             K  I + S  P     +  +  +SR+
Sbjct: 418  PKPAIPSSSVLPSAPRDVVPVLVSSRF 444



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/117 (25%), Positives = 46/117 (39%), Gaps = 9/117 (7%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNK---PLPSGTRYKSTHDFSYVS 2832
            F+S   ++    GD +  +C V     PT  I W  N +   P+P  +R       +   
Sbjct: 142  FLSQTESVTAFMGDTVLLKCEVIGEPMPT--IHWQKNQQDLTPIPGDSRVVVLPSGA--- 196

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSAT-TSGSLRCTGDKNIYFDTQHPQGKAGLEAVE 2888
            L I+     D GIY C A N   S T     +R   D  ++      Q  + + A+E
Sbjct: 197  LQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIE 253



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            +G     + W  NG  +  S   + V   G   L ILG   +D G Y C A N+ G A+ 
Sbjct: 355  SGKPVPTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQT 411

Query: 3135 SVKL 3138
            S +L
Sbjct: 412  SAQL 415


>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
            heparan sulfate  proteoglycan core protein protein.
          Length = 4393

 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 103/424 (24%), Positives = 173/424 (40%), Gaps = 48/424 (11%)

Query: 4394 AQTQERVV--EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI 4451
            AQ Q  V+   G + P  P +  ++ +   V     A       G P   I W +   P+
Sbjct: 3196 AQKQVEVIVDTGAMAPGAPQVQAEEAE-LTVEAGHTATLRCSATGSPARTIHWSKLRSPL 3254

Query: 4452 KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGI 4511
                  +  T      LII +V  +DS  +   A +  G A+ +  L VE          
Sbjct: 3255 PWQHRLEGDT------LIIPRVAQQDSGQYICNATSPAGHAEATIILHVES--------- 3299

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV--QPDIRNKILEEDGTY 4569
             PP  T   ++ +V +G+ V+L     GT P+   W + G  +  +   RN++L  +   
Sbjct: 3300 -PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFE--- 3355

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP- 4628
                  A P+DSG+Y C   N  G A   A+ +V  P     P     A + P   + P 
Sbjct: 3356 -----RAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP-PGSLPATSIPAGSTPTVQVTPQ 3409

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            L+ K +  G ++EF C +       ++W+K    + P        +  +  LRI      
Sbjct: 3410 LETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP------GHSVQDGVLRIQNLDQS 3461

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             +G Y C A+   G+   +A+L V Q   +  +   T ++ +VV  G   +F+       
Sbjct: 3462 CQGTYICQAHGPWGKAQASAQL-VIQALPSVLINIRTSVQTVVV--GHAVEFECLALGDP 3518

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            KP + W + G  +   P   ++  G   V+ I +    D G + C AT AAG  ++   L
Sbjct: 3519 KPQVTWSKVGGHL--RPG--IVQSG--GVVRIAHVELADAGQYRCTATNAAGTTQSHVLL 3572

Query: 4809 VVKS 4812
            +V++
Sbjct: 3573 LVQA 3576



 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 104/422 (24%), Positives = 162/422 (38%), Gaps = 57/422 (13%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQI 4459
            +  PV    PP  T  +QP ++     A F     G P P ++W     P    P   QI
Sbjct: 1865 LSAPVVSIHPPQLT--VQPGQL-----AEFRCSATGSPTPTLEW--TGGPGGQLPAKAQI 1915

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            H      IL +  V   D A +   A +  G     A L V      G GG   P   ++
Sbjct: 1916 HG----GILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVH-----GGGG---PRVQVS 1963

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             +   V +G+ VRL  +  G     + W K G  + P  R+   E     TLLI      
Sbjct: 1964 PERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARS---ERTDIATLLIPAITTA 2020

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G Y CVA + AG A+   + VV   +  D  +P  K  ++ P          V EGQ 
Sbjct: 2021 DAGFYLCVATSPAGTAQARIQVVVL--SASDASQPPVKIESSSPS---------VTEGQT 2069

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            ++ +C + G     V WY+    +        SR      LR+ +  P D G+Y C   N
Sbjct: 2070 LDLNCVVAGSAHAQVTWYRRGGSLPHHTQVHGSR------LRLPQVSPADSGEYVCRVEN 2123

Query: 4700 SAG----RVTVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKP 4750
             +G     +TV+             +P  T P+R       V EGQ       +  +   
Sbjct: 2124 GSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHA 2183

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             + W + G  +P        H+ + ++L +      D+G + C     +G +E S  + +
Sbjct: 2184 QVTWHKRGGSLPAR------HQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2237

Query: 4811 KS 4812
            ++
Sbjct: 2238 EA 2239



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 77/353 (21%), Positives = 149/353 (42%), Gaps = 32/353 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L + QV   DS  +        GT + S  + ++++        V     + + + ++
Sbjct: 2488 SRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASL 2547

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             +G  + L+  V    P  + W K G  +    R++I+       L I +  P DSG+Y 
Sbjct: 2548 ANGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGS----RLRIPQVTPADSGEYV 2601

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C   N AG    +   +V++  +     P+     +PP  IE     +V EGQ ++ +C 
Sbjct: 2602 CHVSNGAGSR--ETSLIVTIQGSGSSHVPRV----SPPIRIESSSPTVV-EGQTLDLNCV 2654

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            +  +P   + WYK G  L  PS++    +T   + LR+ +    D G+Y C A N+   +
Sbjct: 2655 VARQPQAIITWYKRGGSL--PSRH----QTHGSH-LRLHQMSVADSGEYVCRANNNIDAL 2707

Query: 4705 TVAAKLKVTQPDQADNLPALT-PLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + V+    + + P  + P+R       V EG+       +  +    + W + G 
Sbjct: 2708 EASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG 2767

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +P        H+   + L + +    D+G + CR   ++G +E S  + +++
Sbjct: 2768 SLPS------YHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEA 2814



 Score = 81.4 bits (192), Expect = 7e-14
 Identities = 101/413 (24%), Positives = 152/413 (36%), Gaps = 45/413 (10%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIH 4460
            EG     + P+ +       V + + A F+        P+ ++W   N  ++++    +H
Sbjct: 3015 EGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN----VH 3070

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                 SI+ I      +   +  VA N  G A+   NL V            PP+ ++  
Sbjct: 3071 ISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG----------PPTVSVLP 3120

Query: 4521 QN-VNVTSGQLVRLDTKVTGTKPIDVYWLK-NGKKVQPDIRNKILEEDGTYTLLILEAYP 4578
            +  V V  G+ V L+    G       W + +    + + R   L +  T  L I  A P
Sbjct: 3121 EGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHT-VLQISSAKP 3179

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
             D+G Y C+A N+ G A+   E +V   A      PQ +A  A         +  V  G 
Sbjct: 3180 SDAGTYVCLAQNALGTAQKQVEVIVDTGAMA-PGAPQVQAEEA---------ELTVEAGH 3229

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
                 C   G P  T+ W    KL  P  + Q     D  TL I     +D G Y C A 
Sbjct: 3230 TATLRCSATGSPARTIHW---SKLRSPLPW-QHRLEGD--TLIIPRVAQQDSGQYICNAT 3283

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
            + AG       L V  P  A  +P         V  G+  Q +         T QW R G
Sbjct: 3284 SPAGHAEATIILHVESPPYATTVP-----EHASVQAGETVQLQCLAHGTPPLTFQWSRVG 3338

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + +P            N +L       ED+G + CR T   G  E  A+L+V+
Sbjct: 3339 SSLPGRA------TARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQ 3385



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 90/356 (25%), Positives = 148/356 (41%), Gaps = 41/356 (11%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S+L + QV   DS  +        G  + S  + +E     G    +PP   + + +  V
Sbjct: 2203 SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGP---IPP-VRIESSSSTV 2258

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L   V G     V W K G  +    R+++        L I +A P D+G+Y 
Sbjct: 2259 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA--RHQVRGS----RLYIFQASPADAGQYV 2312

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N       +A   V++  T+        A +  P  IEP   + VAEGQ ++ +C 
Sbjct: 2313 CRASNGM-----EASITVTVTGTQGANLAYP-AGSTQPIRIEPSSSQ-VAEGQTLDLNCV 2365

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            + G+    V W+K G  L  P ++           LR+ +A P D G+Y C    S+  V
Sbjct: 2366 VPGQSHAQVTWHKRGGSL--PVRH-----QTHGSLLRLYQASPADSGEYVCRVLGSS--V 2416

Query: 4705 TVAAKLKVTQPDQADNLPAL--TPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWLRE 4757
             + A + VT  + A ++PAL  TP   I      V EGQ       +  +    + W + 
Sbjct: 2417 PLEASVLVTI-EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKR 2475

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            G  +P        H+ + + L +      D+G + CR   ++G  E S  + ++ +
Sbjct: 2476 GGSLPAR------HQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2525



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 99/413 (23%), Positives = 162/413 (39%), Gaps = 45/413 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            S+PP+  +   P  V E +         G     + WYR    + +      HT    S 
Sbjct: 2051 SQPPVKIESSSPS-VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPH------HTQVHGSR 2103

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT----LTAQNV 4523
            L + QV   DS  +    EN  G  + S  + V      G      P  T    +   + 
Sbjct: 2104 LRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSS 2163

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            +V  GQ + L+  V G     V W K G  +    R+   +  G+  L + +  P DSG+
Sbjct: 2164 HVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPA--RH---QTHGSL-LRLHQVTPADSGE 2217

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C  + ++G    +A  +V++ A+   P P       PP  IE      VAEGQ ++ S
Sbjct: 2218 YVCHVVGTSGPL--EASVLVTIEASVI-PGP------IPPVRIES-SSSTVAEGQTLDLS 2267

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C + G+    V WYK    +      + SR      L I +A P D G Y C A N    
Sbjct: 2268 CVVAGQAHAQVTWYKRGGSLPARHQVRGSR------LYIFQASPADAGQYVCRASNGM-E 2320

Query: 4704 VTVAAKLKVTQ-PDQADNLPALTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
             ++   +  TQ  + A    +  P+R       V EGQ       +  +    + W + G
Sbjct: 2321 ASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG 2380

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              +P      + H+ + ++L +      D+G + CR   ++  +E S  + ++
Sbjct: 2381 GSLP------VRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE 2427



 Score = 79.4 bits (187), Expect = 3e-13
 Identities = 95/410 (23%), Positives = 160/410 (39%), Gaps = 52/410 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP  T   +   V   E  + +    G P    +W R    +           +   +L 
Sbjct: 3300 PPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPG------RATARNELLH 3353

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP----PSFTLTAQNVNV 4525
              +   EDS  +     N+ G+A+  A L+V+          +P    P+  +T Q    
Sbjct: 3354 FERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETK 3413

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            + G  V     V   +   + W K G ++ P   + +  +DG   +  L+   Q  G Y 
Sbjct: 3414 SIGASVEFHCAVPSDRGTQLRWFKEGGQLPPG--HSV--QDGVLRIQNLDQSCQ--GTYI 3467

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI--VAEGQAIEFS 4643
            C A    G+A+  A+ V+                 A P ++  ++  +  V  G A+EF 
Sbjct: 3468 CQAHGPWGKAQASAQLVIQ----------------ALPSVLINIRTSVQTVVVGHAVEFE 3511

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C  +G P P V W K    ++P              +RI+     D G Y+C A N+AG 
Sbjct: 3512 CLALGDPKPQVTWSKVGGHLRP------GIVQSGGVVRIAHVELADAGQYRCTATNAAG- 3564

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
             T +  L + Q      LP ++  +++ V  G  A F    +    P I W +    +P 
Sbjct: 3565 TTQSHVLLLVQA-----LPQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLP- 3618

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             PD ++     N +L++ +   +D GT+ C AT   G+V+  A L V  +
Sbjct: 3619 -PDSRL----ENNMLMLPSVQPQDAGTYVCTATNRQGKVKAFAHLQVPER 3663



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 74/305 (24%), Positives = 129/305 (42%), Gaps = 32/305 (10%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V P+  + + +  V  GQ + L+  V G     V W K G  +    R+++    G+  L
Sbjct: 2437 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV---HGS-RL 2490

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             +L+  P DSG+Y C  + S+G    +A  +V++   + +         A P  IE    
Sbjct: 2491 RLLQVTPADSGEYVCRVVGSSGTQ--EASVLVTI---QQRLSGSHSQGVAYPVRIES-SS 2544

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
              +A G  ++ +C +  +   T+ WYK G  L  PS++  +        LRI +  P D 
Sbjct: 2545 ASLANGHTLDLNCLVASQAPHTITWYKRGGSL--PSRHQIVGS-----RLRIPQVTPADS 2597

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQIT 4745
            G+Y C   N AG    +  + + Q   + ++P ++P   I      V EGQ       + 
Sbjct: 2598 GEYVCHVSNGAGSRETSLIVTI-QGSGSSHVPRVSPPIRIESSSPTVVEGQTLDLNCVVA 2656

Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             + +  I W + G  +P        H+ + + L +      D+G + CRA      +E S
Sbjct: 2657 RQPQAIITWYKRGGSLPSR------HQTHGSHLRLHQMSVADSGEYVCRANNNIDALEAS 2710

Query: 4806 AKLVV 4810
              + V
Sbjct: 2711 IVISV 2715



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 82/355 (23%), Positives = 150/355 (42%), Gaps = 35/355 (9%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L I QV   DS  +     N  G+ + S  + ++         + PP   + + +  V
Sbjct: 2585 SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPRVSPP-IRIESSSPTV 2643

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              GQ + L+  V       + W K G  +    R+   +  G++ L + +    DSG+Y 
Sbjct: 2644 VEGQTLDLNCVVARQPQAIITWYKRGGSLPS--RH---QTHGSH-LRLHQMSVADSGEYV 2697

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            C A N+      +A  V+S+  +   P   +   ++ P  IE      VAEG+ ++ +C 
Sbjct: 2698 CRANNNIDAL--EASIVISVSPSAGSP---SAPGSSMPIRIESSSSH-VAEGETLDLNCV 2751

Query: 4646 IVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            + G+    V W+K G  L  PS  +  +R +    LR+    P D G+Y C    S+G +
Sbjct: 2752 VPGQAHAQVTWHKRGGSL--PS--YHQTRGS---RLRLHHVSPADSGEYVCRVMGSSGPL 2804

Query: 4705 TVAAKLKV-TQPDQADNLPA---LTPLR----DIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
              +  + +      A ++PA     P+R       V EGQ    K  +  +    + W +
Sbjct: 2805 EASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHK 2864

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             G  +P        H+ +  +L +      D+G ++C+ T ++G +E S  + ++
Sbjct: 2865 RGGNLPAR------HQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIE 2913



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 77/305 (25%), Positives = 123/305 (40%), Gaps = 31/305 (10%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P   +   +  V  GQ + L   V G     V W K G  +    R+++    G   L +
Sbjct: 2829 PPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPA--RHQV---HGPL-LRL 2882

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
             +  P DSG+Y C    S+G    +A  +V++  +   P P    A   P  IE      
Sbjct: 2883 NQVSPADSGEYSCQVTGSSGTL--EASVLVTIEPSSPGPIPAPGLAQ--PIYIEASSSH- 2937

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            V EGQ ++ +C + G+    V WYK G  L  P+++           LR+    P D G+
Sbjct: 2938 VTEGQTLDLNCVVPGQAHAQVTWYKRGGSL--PARH-----QTHGSQLRLHHVSPADSGE 2990

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI-----VVYEGQPAQFKTQITSK 4747
            Y C A    G    A+      P +  +    +P+  I      V +GQ A FK  I   
Sbjct: 2991 YVCRAAGGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDG 3050

Query: 4748 IKP-TIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
              P +++W      + +      +H   N +++ I  T   + GT+ C A+ A G  ++ 
Sbjct: 3051 AAPISLEWKTRNQELEDN-----VHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSV 3105

Query: 4806 AKLVV 4810
              L V
Sbjct: 3106 VNLSV 3110



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 30/292 (10%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V  GQ + L+  V G     V W K G  +   +R+   +  G+  L + +A P DSG+Y
Sbjct: 2354 VAEGQTLDLNCVVPGQSHAQVTWHKRGGSLP--VRH---QTHGSL-LRLYQASPADSGEY 2407

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
             C  + S+     +A  +V++     +P     A    P +        VAEGQ ++ +C
Sbjct: 2408 VCRVLGSS--VPLEASVLVTI-----EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNC 2460

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             + G+    V W+K    +        SR      LR+ +  P D G+Y C    S+G  
Sbjct: 2461 LVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSGEYVCRVVGSSGTQ 2514

Query: 4705 TVAAKLKVTQ-----PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              +  + + Q       Q    P         +  G        + S+   TI W + G 
Sbjct: 2515 EASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGG 2574

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +P        H+   + L I      D+G + C  +  AG  ETS  + ++
Sbjct: 2575 SLPSR------HQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2620



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 56/177 (31%), Positives = 74/177 (41%), Gaps = 21/177 (11%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G    F+C   G P P+VTW      +R       +V   G   + I +V L+D+G 
Sbjct: 3502 VVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG-----IVQSGG--VVRIAHVELADAGQ 3554

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A N +G T     L V    Q+  P+ V       V  G   V    A G PTP I
Sbjct: 3555 YRCTATNAAGTTQSHVLLLVQALPQISMPQEV------RVPAGSAAVFPCIASGYPTPDI 3608

Query: 523  TWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +W K DG   +P P+ R+      + L +P  +  DA  Y CTA N  G     A L
Sbjct: 3609 SWSKLDG--SLP-PDSRLEN----NMLMLPSVQPQDAGTYVCTATNRQGKVKAFAHL 3658



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 102/486 (20%), Positives = 167/486 (34%), Gaps = 54/486 (11%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G  A+F     G+PTP + WT             +    Q     L +  + P D+ +Y 
Sbjct: 1882 GQLAEFRCSATGSPTPTLEWTGGPGG-------QLPAKAQIHGGILRLPAVEPTDQAQYL 1934

Query: 146  CTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVE--HKAYGTQGYTTEQSRQ 203
            C A +  G+ +    +   G               H   TV    +A G    T    ++
Sbjct: 1935 CRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE 1994

Query: 204  TQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
               +     ++ +      +         +  F   +     G +  +I   +  S    
Sbjct: 1995 GGSLPPQARSERTDIATLLIPAI---TTADAGFYLCVATSPAGTAQARIQVVV-LSASDA 2050

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            S P +  +  +  + EG        ++G+   +VTW++ G     S  H   T  + + L
Sbjct: 2051 SQPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRG----GSLPHH--TQVHGSRL 2104

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
            R+     +DSG Y    EN +G    S  ++V   T S          T         RI
Sbjct: 2105 RLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHS------GPSYTPVPGSTRPIRI 2158

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            E S                V EG+    +C V G+ + +VTW      +   +       
Sbjct: 2159 EPSSS-------------HVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARH------- 2198

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--STLN 501
            ++    L +  VT +DSG   C     SG       L  IE   +  P    R   S+  
Sbjct: 2199 QTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSST 2257

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + L+    G    ++TW K G  +    ++R       S L I +A  +DA  Y
Sbjct: 2258 VAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVR------GSRLYIFQASPADAGQY 2311

Query: 562  QCTAQN 567
             C A N
Sbjct: 2312 VCRASN 2317



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 45/177 (25%), Positives = 76/177 (42%), Gaps = 11/177 (6%)

Query: 395  VKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            V+V  +R  V  G+  R  CR  G P   +TW    R+       +     +    L+I 
Sbjct: 1960 VQVSPERTQVHAGRTVRLYCRAAGVPSATITW----RKEGGSLPPQARSERTDIATLLIP 2015

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
             +T +D+G   CVA + +G    + ++ V+       P      S+ +V EG+ + LN  
Sbjct: 2016 AITTADAGFYLCVATSPAGTAQARIQVVVLSASDASQPPVKIESSSPSVTEGQTLDLNCV 2075

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G+   ++TW + G        L  HT    S L +P+   +D+  Y C  +N +G
Sbjct: 2076 VAGSAHAQVTWYRRG------GSLPHHTQVHGSRLRLPQVSPADSGEYVCRVENGSG 2126



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 80/315 (25%), Positives = 109/315 (34%), Gaps = 41/315 (13%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            SPP     P ++ +Q G   Q Q    G P     W + G  L          T  +  L
Sbjct: 3299 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGR------ATARNELL 3352

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                    DSG Y     N  G       L V+ P  S          T T Q       
Sbjct: 3353 HFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ------- 3405

Query: 384  EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
                  + PQ     + + +  G    F C V      ++ WF    Q+     H +   
Sbjct: 3406 ------VTPQL----ETKSI--GASVEFHCAVPSDRGTQLRWFKEGGQLPP--GHSV--- 3448

Query: 444  ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
            + G   L I N+  S  G   C A    G+     +L VI+    V      R S   V 
Sbjct: 3449 QDG--VLRIQNLDQSCQGTYICQAHGPWGKAQASAQL-VIQALPSVLINI--RTSVQTVV 3503

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             G  V     A+G P P++TW K G  + P     I   GG   + I   + +DA  Y+C
Sbjct: 3504 VGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGG--VVRIAHVELADAGQYRC 3557

Query: 564  TAQNVAGSTATRARL 578
            TA N AG+T +   L
Sbjct: 3558 TATNAAGTTQSHVLL 3572



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 108/530 (20%), Positives = 175/530 (33%), Gaps = 65/530 (12%)

Query: 52   VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
            +E+SG    +    PG   P   E    ++R A+G     +  + G     V+W ++   
Sbjct: 2812 IEASGS-SAVHVPAPGGAPPIRIEP--SSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGN 2868

Query: 112  LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXX 171
            L            Q     L + Q+ P D GEY+C      G    SV +  E       
Sbjct: 2869 LPA--------RHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPI 2920

Query: 172  XXXXXXXYRHVSETVEHKAYGTQ---GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEY 228
                     ++  +  H   G               Q   Y  G    +           
Sbjct: 2921 PAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRL 2980

Query: 229  RLLREVSFRESITKRYVG---ESDVQISTEIDRSLGP---VSPPKIAQKPRNSKLQEGAD 282
              +      E + +   G   E +   +  +  S G    +  P I+  P +S +Q+G D
Sbjct: 2981 HHVSPADSGEYVCRAAGGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQD 3040

Query: 283  AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            A F+  +     P    +K   + +  N H    + N + + +  T+ S+ G Y      
Sbjct: 3041 ASFKCLIHDGAAPISLEWKTRNQELEDNVH---ISPNGSIITIVGTRPSNHGTYR----- 3092

Query: 343  PNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRD 402
               C+ ++ Y   +S     V    +                +S     P +VKV     
Sbjct: 3093 ---CVASNAYGVAQSVVNLSVHGPPT----------------VSVLPEGPVWVKV----- 3128

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
               GK    +C   G P     W  I+    + +     L++   +  L I++   SD+G
Sbjct: 3129 ---GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDS--HTVLQISSAKPSDAG 3183

Query: 462  VVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTP 520
               C+A+N  G    Q  + V        AP+     + L V  G    L   A G+P  
Sbjct: 3184 TYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAR 3243

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             I W K   P+     L         TL IPR    D+  Y C A + AG
Sbjct: 3244 TIHWSKLRSPLPWQHRLE------GDTLIIPRVAQQDSGQYICNATSPAG 3287



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 115/528 (21%), Positives = 187/528 (35%), Gaps = 68/528 (12%)

Query: 62   TAGRPGEPSPPIFEQI-FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            +AG P  P   +  +I   ++  A+G        + G     V+W ++   L        
Sbjct: 2718 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPS------ 2771

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXX 178
             Y++  G   L +  + P D GEY C      G  EA   V I+  G             
Sbjct: 2772 -YHQTRGS-RLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAP 2829

Query: 179  YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV-DTFEYRLLR--EVS 235
               +  +    A   +G T +        A+   T H    +          LLR  +VS
Sbjct: 2830 PIRIEPSSSRVA---EGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVS 2886

Query: 236  FRES--ITKRYVGES---DVQISTEIDRSL-GPVSPPKIAQ----KPRNSKLQEGADAQF 285
              +S   + +  G S   +  +   I+ S  GP+  P +AQ    +  +S + EG     
Sbjct: 2887 PADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2946

Query: 286  QVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
               + G    +VTW+K G  L    +H+   TH  + LR+ +   +DSG Y   A    G
Sbjct: 2947 NCVVPGQAHAQVTWYKRGGSL--PARHQ---THG-SQLRLHHVSPADSGEYVCRAAGGPG 3000

Query: 346  CIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTE 405
                + +     P+E      RS  I+      T                       V +
Sbjct: 3001 PEQEASFTVTVPPSEGSSYRLRSPVISIDPPSST-----------------------VQQ 3037

Query: 406  GKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
            G+   F C +     P  + W   ++++ D+ +    ++ +G+  + I     S+ G   
Sbjct: 3038 GQDASFKCLIHDGAAPISLEWKTRNQELEDNVH----ISPNGS-IITIVGTRPSNHGTYR 3092

Query: 465  CVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
            CVA N  G       L+V     V V P+       + V+ G+ V L   + G P     
Sbjct: 3093 CVASNAYGVAQSVVNLSVHGPPTVSVLPE-----GPVWVKVGKAVTLECVSAGEPRSSAR 3147

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            W +         +         + L I  AK SDA  Y C AQN  G+
Sbjct: 3148 WTRISSTPAKLEQRTYGLMDSHTVLQISSAKPSDAGTYVCLAQNALGT 3195



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 5/133 (3%)

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            N  L I NV LSD+G   C   N          L+V     + AP        L V+ G+
Sbjct: 1824 NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQ 1883

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
                   A G+PTP + W       +P  + +IH  GG   L +P  + +D A Y C A 
Sbjct: 1884 LAEFRCSATGSPTPTLEWTGGPGGQLP-AKAQIH--GG--ILRLPAVEPTDQAQYLCRAH 1938

Query: 567  NVAGSTATRARLY 579
            + AG    RA L+
Sbjct: 1939 SSAGQQVARAVLH 1951



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 12/176 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G++  F C  TG P P + W             K  ++      L +  V  +D   
Sbjct: 1879 VQPGQLAEFRCSATGSPTPTLEWTGGPG---GQLPAKAQIHGG---ILRLPAVEPTDQAQ 1932

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C A + +G+   +  L+V        P+         V  G  V L  RA G P+  I
Sbjct: 1933 YLCRAHSSAGQQVARAVLHV---HGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATI 1989

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            TW+K+G  + P       TD   +TL IP    +DA +Y C A + AG+   R ++
Sbjct: 1990 TWRKEGGSLPPQARSE-RTD--IATLLIPAITTADAGFYLCVATSPAGTAQARIQV 2042



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 14/173 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + +GQ A ++  LI  G   + +EW    + +E +  I    +    ++ I+GT+ ++ G
Sbjct: 3035 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHG 3089

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
            TY C A+N +G A+  V L     S    P  +   +    +K G++   EC  V   +P
Sbjct: 3090 TYRCVASNAYGVAQSVVNL-----SVHGPPTVSVLPEGPVWVKVGKAVTLEC--VSAGEP 3142

Query: 3180 DMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                 W   +  P +   R   + D    VL I+  +  D+G YVC A N  G
Sbjct: 3143 RSSARWTRISSTPAKLEQRTYGLMD-SHTVLQISSAKPSDAGTYVCLAQNALG 3194



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 8/140 (5%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I   + +D+GTY C  +N +   + +  L          P  + H   +  ++ GQ 
Sbjct: 1826 ILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT-VQPGQL 1884

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A F C+      P   +EW   G P     ++   +     +L +   +  D  +Y+CRA
Sbjct: 1885 AEFRCSAT--GSPTPTLEW--TGGP---GGQLPAKAQIHGGILRLPAVEPTDQAQYLCRA 1937

Query: 3227 YNKYGEDFTRATINCYGKGG 3246
            ++  G+   RA ++ +G GG
Sbjct: 1938 HSSAGQQVARAVLHVHGGGG 1957



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 80/320 (25%), Positives = 123/320 (38%), Gaps = 52/320 (16%)

Query: 261  GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
            G   P +I  +P +S++ EG        + G    +VTW K G  L    +H+   TH  
Sbjct: 2340 GSTQPIRI--EPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSL--PVRHQ---THG- 2391

Query: 321  TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
            + LR+     +DSG Y       +  +  S  + +E P  S      +  +T T      
Sbjct: 2392 SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE-PAGSVP----ALGVTPTV----- 2441

Query: 381  ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
             RIE S   +A             EG+    +C V G+ + +VTW      +     H++
Sbjct: 2442 -RIESSSSQVA-------------EGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV 2485

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGE------TAFQCRLNVIEKEQVVAPKFV 494
                 G+  L +  VT +DSG   C     SG          Q RL+    + V  P  +
Sbjct: 2486 ----HGSR-LRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRI 2540

Query: 495  ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
            E  S+ ++  G  + LN          ITW K G  +    ++        S L IP+  
Sbjct: 2541 ES-SSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI------VGSRLRIPQVT 2593

Query: 555  ASDAAWYQCTAQNVAGSTAT 574
             +D+  Y C   N AGS  T
Sbjct: 2594 PADSGEYVCHVSNGAGSRET 2613



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 52/231 (22%), Positives = 81/231 (35%), Gaps = 20/231 (8%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H++          L +L     DSG
Sbjct: 2450 VAEGQTL--DLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSR------LRLLQVTPADSG 2501

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CR     G  E SV +    +  G   +   +   IE     L +G +    C V  
Sbjct: 2502 EYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVA- 2560

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
                   I WY  G  +   +R + V       L I      DSGEYVC   N  G   T
Sbjct: 2561 -SQAPHTITWYKRGGSL--PSRHQIVGSR----LRIPQVTPADSGEYVCHVSNGAGSRET 2613

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
               +   G G  ++  + P    +      ++G         + +P   IT
Sbjct: 2614 SLIVTIQGSGSSHVPRVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIIT 2664



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 40/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  S  I W   G ++    R        +  L I    T D+G Y C AT+  G A+  
Sbjct: 1983 GVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCVATSPAGTAQAR 2039

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
            +++  +  S   +P       +   + +GQ+    C V        ++ WY  G  + H 
Sbjct: 2040 IQVVVLSASDASQPPVKIE-SSSPSVTEGQTLDLNCVV--AGSAHAQVTWYRRGGSLPHH 2096

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
            T++          L +      DSGEYVCR  N  G      T++
Sbjct: 2097 TQVHGSR------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2135



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 60/246 (24%), Positives = 95/246 (38%), Gaps = 42/246 (17%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E TI     +PP +   + ++  V  G  V   C     G P +   W   G       R
Sbjct: 3290 EATIILHVESPP-YATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLP--GR 3344

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
                N+     L  +     D+G Y CR TNK GSA   A++        +  + +P G 
Sbjct: 3345 ATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGS 3400

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            +                   P V   P    Q+++ ++  S  V F C V      +LR 
Sbjct: 3401 T-------------------PTVQVTP----QLETKSIGAS--VEFHCAVPSDRGTQLR- 3434

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             W++ G  LP GH   +V D G + +  L    +  G YIC+A   +G+    A +  + 
Sbjct: 3435 -WFKEGGQLPPGH---SVQD-GVLRIQNLDQSCQ--GTYICQAHGPWGKAQASAQLVIQA 3487

Query: 3924 LPDIIL 3929
            LP +++
Sbjct: 3488 LPSVLI 3493



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 18/155 (11%)

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
            D+   + WF  G  +   H ++        VL I     +  GTY C+A   WG+A+ S 
Sbjct: 3428 DRGTQLRWFKEGGQLPPGHSVQDG------VLRIQNLDQSCQGTYICQAHGPWGKAQASA 3481

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            +L  +           T +Q +     G +  FEC  + + DP  ++ W   G  +R   
Sbjct: 3482 QL-VIQALPSVLINIRTSVQTV---VVGHAVEFEC--LALGDPKPQVTWSKVGGHLRPG- 3534

Query: 3197 RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                V   G  V+ IA+ +  D+G+Y C A N  G
Sbjct: 3535 ---IVQSGG--VVRIAHVELADAGQYRCTATNAAG 3564



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 56/240 (23%), Positives = 91/240 (37%), Gaps = 44/240 (18%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            ++P +   +    +++ GE    +     T  P L  +W   G SL   +  R       
Sbjct: 3298 ESPPYATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARN------ 3349

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537
             +L      PEDSG Y CR  N  G A   A + VQG    +  + +P G   T+     
Sbjct: 3350 ELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQ---- 3405

Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
                      +TP+ E+               S  +S  F C  +P +D   ++ WF  G
Sbjct: 3406 ----------VTPQLET--------------KSIGASVEFHC-AVP-SDRGTQLRWFKEG 3439

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
              L  G  V+        +L I  + Q   G Y C+A    G+A  S +L ++    +++
Sbjct: 3440 GQLPPGHSVQD------GVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLI 3493



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 25/174 (14%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    +  ++P G     + W   G  + A H++         +L +      DSG
Sbjct: 2840 VAEGQTLDLKC-VVP-GQAHAQVTWHKRGGNLPARHQVHGP------LLRLNQVSPADSG 2891

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKP----RFTTHIQ-NIEGLKDGQSAHFECTVV 3174
             YSC+ T   G  E SV +     S G  P        +I+ +   + +GQ+    C VV
Sbjct: 2892 EYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VV 2950

Query: 3175 PVDDPDMKIEWYHNG--QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            P      ++ WY  G   P RH T            L + +    DSGEYVCRA
Sbjct: 2951 P-GQAHAQVTWYKRGGSLPARHQTHGSQ--------LRLHHVSPADSGEYVCRA 2995



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 2377 VFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSM 2436
            V T P ++I     GQT  F C  I V  P L + W  N   I    R+T T + G  ++
Sbjct: 408  VVTPPRESIQ-ASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRVTVTSEGGRGTL 465

Query: 2437 TISHVRDEDEGVYMCRASNLLG 2458
             I  V++ D+G Y C A N  G
Sbjct: 466  IIRDVKESDQGAYTCEAMNARG 487



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 25/172 (14%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + S +  G     + W+  G ++ A H++R    +      I      D+G
Sbjct: 2258 VAEGQTL--DLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLY------IFQASPADAG 2309

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVP 3175
             Y CRA+N   +A I+V +     +    P  +T    IE     + +GQ+    C VVP
Sbjct: 2310 QYVCRASNGM-EASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC-VVP 2367

Query: 3176 VDDPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                  ++ W+  G   P+RH T           +L +      DSGEYVCR
Sbjct: 2368 -GQSHAQVTWHKRGGSLPVRHQTHGS--------LLRLYQASPADSGEYVCR 2410



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 42/188 (22%), Positives = 76/188 (40%), Gaps = 17/188 (9%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W+  G ++ A H+           L +      DSG
Sbjct: 2938 VTEGQTL--DLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQ------LRLHHVSPADSG 2989

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE----GLKDGQSAHFECTVVP 3175
             Y CRA    G  + +     V  S+G   R  + + +I+     ++ GQ A F+C +  
Sbjct: 2990 EYVCRAAGGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHD 3049

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               P + +EW    Q +  +  I         ++ I  T+  + G Y C A N YG   +
Sbjct: 3050 GAAP-ISLEWKTRNQELEDNVHISPNGS----IITIVGTRPSNHGTYRCVASNAYGVAQS 3104

Query: 3236 RATINCYG 3243
               ++ +G
Sbjct: 3105 VVNLSVHG 3112



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 47/153 (30%), Positives = 62/153 (40%), Gaps = 23/153 (15%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W+  G ++ + H+I      G   L I      DSG Y C  +N  G  E S+ +   
Sbjct: 2567 ITWYKRGGSLPSRHQI-----VGSR-LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQ 2620

Query: 3142 DKSKGQKPRFTTHIQNIEG----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQ--PMRHS 3195
                   PR +  I+ IE     + +GQ+    C V     P   I WY  G   P RH 
Sbjct: 2621 GSGSSHVPRVSPPIR-IESSSPTVVEGQTLDLNCVVAR--QPQAIITWYKRGGSLPSRHQ 2677

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            T     S      + +A     DSGEYVCRA N
Sbjct: 2678 TH---GSHLRLHQMSVA-----DSGEYVCRANN 2702



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 12/126 (9%)

Query: 4583 KYECVAINSAGEA--RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQA 4639
            ++ CV+ N    A   CD E         D P    +    PP+++ P ++ I A  GQ 
Sbjct: 372  QFRCVSTNMCIPASFHCDEE--------SDCPDRSDEFGCMPPQVVTPPRESIQASRGQT 423

Query: 4640 IEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            + F+C  +G P P  + W      I       ++      TL I +    D+G Y C A 
Sbjct: 424  VTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAM 483

Query: 4699 NSAGRV 4704
            N+ G V
Sbjct: 484  NARGMV 489



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 75/306 (24%), Positives = 118/306 (38%), Gaps = 46/306 (15%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P +  +  +S++ EG        ++G    +VTW K G  L    +H++    + + LR+
Sbjct: 2439 PTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL--PARHQV----HGSRLRL 2492

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
                 +DSG Y         C V       E+     +Q + S   + +Q      RIE 
Sbjct: 2493 LQVTPADSGEYV--------CRVVGSSGTQEASVLVTIQQRLSG--SHSQGVAYPVRIES 2542

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            S  +LA              G     +C V  +    +TW+     +     H+I+ +  
Sbjct: 2543 SSASLA-------------NGHTLDLNCLVASQAPHTITWYKRGGSLPS--RHQIVGSR- 2586

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQV--VAPKFVERFSTLN 501
                L I  VT +DSG   C   N +G  ET+    +       V  V+P      S+  
Sbjct: 2587 ----LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPRVSPPIRIESSSPT 2642

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            V EG+ + LN      P   ITW K G   +P+   R  T G  S L + +   +D+  Y
Sbjct: 2643 VVEGQTLDLNCVVARQPQAIITWYKRG-GSLPS---RHQTHG--SHLRLHQMSVADSGEY 2696

Query: 562  QCTAQN 567
             C A N
Sbjct: 2697 VCRANN 2702



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 8/108 (7%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            + P + T +    S+   ET + +C LA  G P +  +W   G  L    R T   +   
Sbjct: 3298 ESPPYATTVPEHASVQAGETVQLQC-LAH-GTPPLTFQWSRVGSSL--PGRATARNEL-- 3351

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP 4078
              ++F    PEDSG Y CR TN  G  E  A +   G PG +  + +P
Sbjct: 3352 --LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIP 3397



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 58/239 (24%), Positives = 87/239 (36%), Gaps = 19/239 (7%)

Query: 4581 SGKYECVAINSAGEARCDAEC---VVSLPATKD-KPKPQTKAANAPPEIIEPLKDKIVAE 4636
            +G Y C A       +   +C    V  P+ +  +  P+T  A    E+  P +  IV +
Sbjct: 1635 AGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEV-HPARS-IVPQ 1692

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G +    C++ G+      W + D    PS   Q  + ++   L      P D G Y C 
Sbjct: 1693 GGSHSLRCQVSGRGPHYFYWSREDGRPVPSGTQQRHQGSE---LHFPSVQPSDAGVYICT 1749

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP-TIQWL 4755
              N     T  A+L VT+         +   R   V  G    F     SK    T+ W 
Sbjct: 1750 CRNLHRSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWT 1809

Query: 4756 R--EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            R   G L     DF       N +L I N    D GT+ C  +      + +A L V++
Sbjct: 1810 RLHNGKLPTRAMDF-------NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQA 1861



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 1/73 (1%)

Query: 499 TLNVREGEPVVLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           ++    G+ V     A+G P P  I W+ +   I   P + + ++GG  TL I   K SD
Sbjct: 415 SIQASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTVTSEGGRGTLIIRDVKESD 474

Query: 558 AAWYQCTAQNVAG 570
              Y C A N  G
Sbjct: 475 QGAYTCEAMNARG 487



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 29/218 (13%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            +I W+  G ++ + H+    +      L +      DSG Y CRA N     E S+ +  
Sbjct: 2662 IITWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVIS- 2714

Query: 3141 VDKSKG--QKPRFTTHIQ---NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG--QPMR 3193
            V  S G    P  +  I+   +   + +G++    C VVP      ++ W+  G   P  
Sbjct: 2715 VSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC-VVP-GQAHAQVTWHKRGGSLPSY 2772

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATINCYGKGGVYLES 3251
            H TR           L + +    DSGEYVCR     G  E     TI   G   V++ +
Sbjct: 2773 HQTRGSR--------LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPA 2824

Query: 3252 LQPDSLAKIR-ELESLQGAQQQTPSTPSAEPPKFITQI 3288
              P     IR E  S + A+ QT       P +   Q+
Sbjct: 2825 --PGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQV 2860



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQ 3165
            VL+I   K +D+GTY C A N  G A+  V++  VD             +  E  ++ G 
Sbjct: 3171 VLQISSAKPSDAGTYVCLAQNALGTAQKQVEV-IVDTGAMAPGAPQVQAEEAELTVEAGH 3229

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A   C+      P   I W     P+    R++   D     L I      DSG+Y+C 
Sbjct: 3230 TATLRCSA--TGSPARTIHWSKLRSPLPWQHRLE--GD----TLIIPRVAQQDSGQYICN 3281

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
            A +  G     ATI  + +   Y  ++   +  +  E   LQ     TP
Sbjct: 3282 ATSPAGH--AEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTP 3328



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADN---LP--ALTPLRD-IVVYEGQPAQFKTQITS 4746
            ++CV+ N     +     +   PD++D    +P   +TP R+ I    GQ   F      
Sbjct: 373  FRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIG 432

Query: 4747 KIKP-TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
               P  I W      IP  P   +  EG    L+I +  E D G +TC A  A G V
Sbjct: 433  VPAPFLINWRLNWGHIPSQPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMV 489



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 55/239 (23%), Positives = 90/239 (37%), Gaps = 44/239 (18%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            +S   + EG      C V     P   I W+  G  + + H+   +H      L +    
Sbjct: 2638 SSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH------LRLHQMS 2689

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE 2235
              DSG Y+C+A N +           A   +I++      G        A G S  I +E
Sbjct: 2690 VADSGEYVCRANNNID----------ALEASIVISVSPSAGSPS-----APGSSMPIRIE 2734

Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295
                           ++HV EG+T    C V      + ++ ++  G +L S   +H T 
Sbjct: 2735 S-------------SSSHVAEGETLDLNCVVPG--QAHAQVTWHKRGGSLPS---YHQTR 2776

Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIR 2354
                  L + H  P D+GEY  + + + G   +++ +T+ A GS       P G   IR
Sbjct: 2777 GS---RLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIR 2832



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 22/52 (42%), Positives = 27/52 (51%)

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAF 2996
            I W  N   +    R  +TS+ G  TL + DV E D G YTC+A N RG  F
Sbjct: 439  INWRLNWGHIPSQPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVF 490



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 54/212 (25%), Positives = 78/212 (36%), Gaps = 19/212 (8%)

Query: 368  SQYITDTQQRETEERIEISEKAL-APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
            +Q    T Q++ E  ++    A  APQ      +  V  G      C  TG P   + W 
Sbjct: 3189 AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPARTIHW- 3247

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
             +  +    + H++     G+  L+I  V   DSG   C A + +G       L+V  + 
Sbjct: 3248 -SKLRSPLPWQHRL----EGD-TLIIPRVAQQDSGQYICNATSPAGHAEATIILHV--ES 3299

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
               A    E  S   V+ GE V L   A GTP     W + G  +      R        
Sbjct: 3300 PPYATTVPEHAS---VQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR------NE 3350

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             L   RA   D+  Y+C   N  GS    A+L
Sbjct: 3351 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQL 3382



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 12/117 (10%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            T+  + +  +AL PQ + + Q+  V  G    F C  +G P P+++W   D  +  D   
Sbjct: 3566 TQSHVLLLVQAL-PQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPD--- 3620

Query: 439  KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
                +   N+ LM+ +V   D+G   C A N+ G+      L V E+   V P F +
Sbjct: 3621 ----SRLENNMLMLPSVQPQDAGTYVCTATNRQGKVKAFAHLQVPER---VVPYFTQ 3670



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 55/218 (25%), Positives = 79/218 (36%), Gaps = 27/218 (12%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EGQ    + + +  G     + W   G ++ A H+          +L +      DSG
Sbjct: 2165 VAEGQTL--DLNCVVPGQAHAQVTWHKRGGSLPARHQTHGS------LLRLHQVTPADSG 2216

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDD 3178
             Y C      G  E SV L  ++ S    P     I++    + +GQ+    C V     
Sbjct: 2217 EYVCHVVGTSGPLEASV-LVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA--GQ 2273

Query: 3179 PDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
               ++ WY  G   P RH  R           L I      D+G+YVCRA N      T 
Sbjct: 2274 AHAQVTWYKRGGSLPARHQVRGSR--------LYIFQASPADAGQYVCRASNGMEASITV 2325

Query: 3237 ATINCYGKGGVY-LESLQPDSLAKIRELESLQGAQQQT 3273
                  G    Y   S QP  +    E  S Q A+ QT
Sbjct: 2326 TVTGTQGANLAYPAGSTQPIRI----EPSSSQVAEGQT 2359



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
            V T P + I+ +  Q   F    I V  P L + W  N   I +  R+T   + G   L 
Sbjct: 408  VVTPPRESIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRVTVTSEGGRGTLI 466

Query: 1772 MKYVNPEDSGTYTCRAINELG 1792
            ++ V   D G YTC A+N  G
Sbjct: 467  IRDVKESDQGAYTCEAMNARG 487



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 62/267 (23%), Positives = 97/267 (36%), Gaps = 46/267 (17%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            DSG Y C AT+  G AE ++ L        + P + T +     ++ G++   +C  +  
Sbjct: 3274 DSGQYICNATSPAGHAEATIILHV------ESPPYATTVPEHASVQAGETVQLQC--LAH 3325

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P +  +W   G  +      +        +L        DSG Y CR  NK G     
Sbjct: 3326 GTPPLTFQWSRVGSSLPGRATARNE------LLHFERAAPEDSGRYRCRVTNKVGSAEAF 3379

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A +   G  G                  SL        STP+ +    +T  Q  TK + 
Sbjct: 3380 AQLLVQGPPG------------------SLPATSIPAGSTPTVQ----VTP-QLETKSI- 3415

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356
            G S  F    VP  D   ++ WF  G +LP GH  +        +L I    +   G Y 
Sbjct: 3416 GASVEFHC-AVP-SDRGTQLRWFKEGGQLPPGHSVQD------GVLRIQNLDQSCQGTYI 3467

Query: 3357 CVATNKLGRDSTKANLKCTSKENLILD 3383
            C A    G+    A L   +  +++++
Sbjct: 3468 CQAHGPWGKAQASAQLVIQALPSVLIN 3494



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 52/218 (23%), Positives = 76/218 (34%), Gaps = 13/218 (5%)

Query: 385  ISEKALAPQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWFIND-RQIRDDYNHKILV 442
            + E   AP  V+V   R +  +G      C+V+GR      W   D R +      +   
Sbjct: 1671 LPETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGRGPHYFYWSREDGRPVPSGTQQRHQG 1730

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +E     L   +V  SD+GV  C  RN       +  L V E         VE   + +V
Sbjct: 1731 SE-----LHFPSVQPSDAGVYICTCRNLHRSNTSRAELLVTEAPSKPITVTVEEQRSQSV 1785

Query: 503  REGEPVVLNARAVG-TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            R G  V     A   +P   + W +     + N +L          L I   + SDA  Y
Sbjct: 1786 RPGADVTFICTAKSKSPAYTLVWTR-----LHNGKLPTRAMDFNGILTIRNVQLSDAGTY 1840

Query: 562  QCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPT 599
             CT  N+       A L+             +H P+ T
Sbjct: 1841 VCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLT 1878



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 29/112 (25%), Positives = 44/112 (39%), Gaps = 2/112 (1%)

Query: 4505 RQGRGGIVPPSF-TLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLKNGKKVQPDIRNKI 4562
            R    G +PP   T   +++  + GQ V       G   P  + W  N   +    R  +
Sbjct: 397  RSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTV 456

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
              E G  TL+I +    D G Y C A+N+ G      + V+ L   +  P P
Sbjct: 457  TSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVFGIPDGVLELVPQRAGPCP 508



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 3824 PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            P VS P +   +  S TV E + +   C V     P+  I WY+ G  LPS H+    + 
Sbjct: 2628 PRVSPPIRI--ESSSPTVVEGQTLDLNCVVA--RQPQAIITWYKRGGSLPSRHQTHGSH- 2682

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVND 3909
                 L +  +   DSGEY+CRA N+
Sbjct: 2683 -----LRLHQMSVADSGEYVCRANNN 2703



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+ +T      + S GQ+  + C     P P + + W  N   + S  R   +++ G   
Sbjct: 406  PQVVTPPRESIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRVTVTSEGGRGT 464

Query: 1904 LDILTVYGEDSGEYTCKAINNLG 1926
            L I  V   D G YTC+A+N  G
Sbjct: 465  LIIRDVKESDQGAYTCEAMNARG 487



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR-NGVPIEASNRLTTMHDFGYVAL 1770
            V  +P   + V   +A   E   +  G+P+    W R +  P +   R   + D  +  L
Sbjct: 3116 VSVLPEGPVWVKVGKAVTLEC--VSAGEPRSSARWTRISSTPAKLEQRTYGLMD-SHTVL 3172

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +    P D+GTY C A N LG A     + V + A
Sbjct: 3173 QISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGA 3208



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q+GQ A F C LI  G   + +EW    + +ED+  I+         +TI   R  + G
Sbjct: 3035 VQQGQDASFKC-LIHDGAAPISLEWKTRNQELEDNVHISPNGSI----ITIVGTRPSNHG 3089

Query: 2448 VYMCRASNLLG 2458
             Y C ASN  G
Sbjct: 3090 TYRCVASNAYG 3100



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 1568 DMVDEVTTQAP-ICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF 1626
            D  DE     P + T   ++++   GQ   F    I V  A   + W  N   + S  R 
Sbjct: 396  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVP-APFLINWRLNWGHIPSQPRV 454

Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            T T+  G   L I      D G YTC A+NA G
Sbjct: 455  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 487



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 10/96 (10%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D  QPP  V    S  S+ E +T    C +A  G  + +V W+  G  L H    T ++ 
Sbjct: 2049 DASQPP--VKIESSSPSVTEGQTLDLNCVVA--GSAHAQVTWYRRGGSLPHH---TQVHG 2101

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
                 +    V P DSGEY+CR  N  G  E    +
Sbjct: 2102 S---RLRLPQVSPADSGEYVCRVENGSGPKEASITV 2134



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 12/122 (9%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI--RAGHRYRTTHDF 2164
            + P + T +    +++ G+    +C       P LT  W   G  +  RA  R    H F
Sbjct: 3298 ESPPYATTVPEHASVQAGETVQLQCLAH--GTPPLTFQWSRVGSSLPGRATARNELLH-F 3354

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
               A        EDSG Y C+ TNK+G A     L V G    +  T  P G     Q+ 
Sbjct: 3355 ERAA-------PEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3407

Query: 2225 AQ 2226
             Q
Sbjct: 3408 PQ 3409



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 6/66 (9%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P L  +W R G  +    R T  ++     L+ +   PEDSG Y CR  N++G A   
Sbjct: 3326 GTPPLTFQWSRVGSSLPG--RATARNEL----LHFERAAPEDSGRYRCRVTNKVGSAEAF 3379

Query: 1798 STLFVQ 1803
            + L VQ
Sbjct: 3380 AQLLVQ 3385



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 10/111 (9%)

Query: 3825 IVSTPPKFITQIKS--HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            ++   P  +  I++   TV     V FEC      DPK ++ W + G     GH    + 
Sbjct: 3484 VIQALPSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GHLRPGIV 3536

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
              G V + I +V   D+G+Y C A N  G   +   +  + LP I +  +V
Sbjct: 3537 QSGGV-VRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEV 3586



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 5/100 (5%)

Query: 2495 ERRSEEPDREFEKPIFT-QVLTGPSELWE---GQHAHYEARVVPVGDPSLRFEWYINGVE 2550
            +  S+ PDR  E      QV+T P E  +   GQ   +    + V  P L   W +N   
Sbjct: 389  DEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGH 447

Query: 2551 LKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +    R   T + G  TL I  V  +D G Y C+A+N  G
Sbjct: 448  IPSQPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 487



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 265 PPKIAQKPRNS-KLQEGADAQFQVQLSGNPRP-RVTWFKNGQRLINSNKHEIITTHNHTT 322
           PP++   PR S +   G    F     G P P  + W  N   + +  +  + +     T
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTVTSEGGRGT 464

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCI 347
           L +R+ ++SD G YT  A N  G +
Sbjct: 465 LIIRDVKESDQGAYTCEAMNARGMV 489



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 1/74 (1%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            +I    G  + F C       P L I W  N   +PS  R   T +    +L I    E 
Sbjct: 415  SIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRVTVTSEGGRGTLIIRDVKES 473

Query: 2842 DSGIYTCKATNSKG 2855
            D G YTC+A N++G
Sbjct: 474  DQGAYTCEAMNARG 487



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 10/110 (9%)

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +EP   +  +  +  V ++  S+   V+EG+ + L C +   G    +V W   G S+  
Sbjct: 2426 IEPAGSVPALGVTPTVRIE--SSSSQVAEGQTLDLNCLVA--GQAHAQVTWHKRGGSLP- 2480

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             +R + +       L ++  T AD+GEY  R V   G+   S +V + +R
Sbjct: 2481 -ARHQVHGS----RLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2525



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 53/231 (22%), Positives = 77/231 (33%), Gaps = 45/231 (19%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P   +     +VAE Q    +   +  G    +V W + G        L   H      L
Sbjct: 2439 PTVRIESSSSQVAEGQT--LDLNCLVAGQAHAQVTWHKRG------GSLPARHQVHGSRL 2490

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +  V P DSG Y CR +   G    S  + +Q +    L   H   +    ++E SS  
Sbjct: 2491 RLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR----LSGSHSQGVAYPVRIESSS-- 2544

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
                                     L+ G +    C +     P+  + WY  G  L S 
Sbjct: 2545 -----------------------ASLANGHTLDLNCLVASQA-PH-TITWYKRGGSLPSR 2579

Query: 1891 HRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            H+   S       L I  V   DSGEY C   N  G   +S+ + +Q   S
Sbjct: 2580 HQIVGSR------LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2624



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 47/178 (26%), Positives = 67/178 (37%), Gaps = 38/178 (21%)

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
            L + H      L +  V P DSG Y C   N  G   TS  + +Q        S H   +
Sbjct: 2576 LPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSG-----SSHVPRV 2630

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
                ++E SS                        PT + EGQ+    C +     P   +
Sbjct: 2631 SPPIRIESSS------------------------PTVV-EGQTLDLNCVVAR--QPQAII 2663

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             WY  G  L S H+   S+      L +  +   DSGEY C+A NN+    +SI ++V
Sbjct: 2664 TWYKRGGSLPSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2715



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP+ VT  R +     G+T  F C    V  P L I +  N   + S  R  +T + G  
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRVTVTSEGGRG 463

Query: 2301 SLDIQHCVPEDAGEYSVKAINALG 2324
            +L I+     D G Y+ +A+NA G
Sbjct: 464  TLIIRDVKESDQGAYTCEAMNARG 487



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP+  T P + I  S   +  F C  I V  +   + W  N   + +  RV   ++ G  
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVAIGV-PAPFLINWRLNWGHIPSQPRVTVTSEGGRG 463

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHG 3639
             L I  V + D G YTC+A N  G
Sbjct: 464  TLIIRDVKESDQGAYTCEAMNARG 487



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 20/129 (15%)

Query: 3978 QIQSQTSLV-EMETTKFECQLAPVGDPNMKVEWFFNGK--PLLHKNRFTPIYDFGYVAMN 4034
            +I+S +S V E +T    C +A  G  + +V W+  G   P  H+ R + +Y F      
Sbjct: 2250 RIESSSSTVAEGQTLDLSCVVA--GQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ----- 2302

Query: 4035 FGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASW 4094
                 P D+G+Y+CRA+N  GM E    +  TG  G    + L     S + IR   +S 
Sbjct: 2303 ---ASPADAGQYVCRASN--GM-EASITVTVTGTQG----ANLAYPAGSTQPIRIEPSSS 2352

Query: 4095 QVTPEQVVE 4103
            QV   Q ++
Sbjct: 2353 QVAEGQTLD 2361



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 9/92 (9%)

Query: 3823 EPIVSTPPKFIT---QIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            EP  S P   +T   +I+S + + +EG   +           ++ W++ G  LP+ H+  
Sbjct: 2427 EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVH 2486

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                     L +L V   DSGEY+CR V   G
Sbjct: 2487 GS------RLRLLQVTPADSGEYVCRVVGSSG 2512



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 1/93 (1%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            D  DE   + P+ VT P+       GQ V F C    V    L + W  N   +    R 
Sbjct: 396  DRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRV 454

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
                + G   L I D+   D G YTC A+N  G
Sbjct: 455  TVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 487



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)

Query: 636 PPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPQ + P + S+ A  G  + F      V  P + I W  N   I +  R T     G  
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRVTVTSEGGRG 463

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGV 719
           +L +  +   D G YTC A++A G+
Sbjct: 464 TLIIRDVKESDQGAYTCEAMNARGM 488



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 51/232 (21%), Positives = 93/232 (40%), Gaps = 47/232 (20%)

Query: 2223 LEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
            +EA G S+ + V  P  +PP  +     ++ V EG+T   +C V      + ++ ++  G
Sbjct: 2812 IEASG-SSAVHVPAPGGAPPIRIEP--SSSRVAEGQTLDLKCVVPG--QAHAQVTWHKRG 2866

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIIS 2342
              L +  + H         L +    P D+GEYS +   + G   +++ +T+        
Sbjct: 2867 GNLPARHQVHGPL------LRLNQVSPADSGEYSCQVTGSSGTLEASVLVTI-------- 2912

Query: 2343 ESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIP 2402
                             EP     IP P   Q P++ +   +  ++ EGQT   +C ++P
Sbjct: 2913 -----------------EPSSPGPIPAPGLAQ-PIYIEASSS--HVTEGQTLDLNC-VVP 2951

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
             G    +V W++          +   H      + + HV   D G Y+CRA+
Sbjct: 2952 -GQAHAQVTWYKR------GGSLPARHQTHGSQLRLHHVSPADSGEYVCRAA 2996



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            ++P+ +    +  +++GQ A F + LI    A + +EW   N+ L+     +   +    
Sbjct: 3022 RSPVISIDPPSSTVQQGQDASF-KCLIHDGAAPISLEWKTRNQELEDNVHISPNGSI--- 3077

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             + I+   P + GTY C A NA G A +     VH   ++
Sbjct: 3078 -ITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTV 3116



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 11/124 (8%)

Query: 3826 VSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V +PP + T +  H +V+  E V+ +C       P L  +W R G  LP     R     
Sbjct: 3297 VESPP-YATTVPEHASVQAGETVQLQCLAHGT--PPLTFQWSRVGSSLPGRATARNEL-- 3351

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
                L       EDSG Y CR  N  G     A +  +  P  +    +P G   +  +T
Sbjct: 3352 ----LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVT 3407

Query: 3945 -QME 3947
             Q+E
Sbjct: 3408 PQLE 3411



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 4/99 (4%)

Query: 3035 EPGQQPD--DDTG-RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI 3091
            E    PD  D+ G  PP+  T  ++ +  S GQ   +    I       +I W  N   I
Sbjct: 390  EESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGV-PAPFLINWRLNWGHI 448

Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
             +  R+      G   L I   K +D G Y+C A N  G
Sbjct: 449  PSQPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 487



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            S P+ ++  S+ P V EG+ + L C +     P   + W+  G S+   SR +T+     
Sbjct: 2631 SPPIRIE--SSSPTVVEGQTLDLNCVVARQ--PQAIITWYKRGGSLP--SRHQTHGSH-- 2682

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +   + AD+GEY  RA N++ +   S ++ V
Sbjct: 2683 --LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2715



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 8/96 (8%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            APV ++    +  ++ G+ A F    T +  P L+    W G     G +          
Sbjct: 1867 APVVSIHPPQL-TVQPGQLAEFRCSATGSPTPTLE----WTGGP---GGQLPAKAQIHGG 1918

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            IL +    P D  +YLCRA+++ G+ V  A + V G
Sbjct: 1919 ILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHG 1954



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 9/87 (10%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            +  R   G  A F     G PTP +SW++           S+  + +  +  L++  + P
Sbjct: 3584 QEVRVPAGSAAVFPCIASGYPTPDISWSKLDG--------SLPPDSRLENNMLMLPSVQP 3635

Query: 139  GDEGEYTCTARNQYGEAICSVYIQ-PE 164
             D G Y CTA N+ G+     ++Q PE
Sbjct: 3636 QDAGTYVCTATNRQGKVKAFAHLQVPE 3662



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 9/95 (9%)

Query: 3822 EEPIVSTP-PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            E  ++  P P    +  S TV E + +   C V  +   +  + WY+ G  LP+ H+ R 
Sbjct: 2238 EASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQ--VTWYKRGGSLPARHQVRG 2295

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT 3915
                    L I      D+G+Y+CRA N      T
Sbjct: 2296 ------SRLYIFQASPADAGQYVCRASNGMEASIT 2324



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 9/85 (10%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            S+ P  I    SH V E E +   C V P +    ++ W++ G  LPS H+ R       
Sbjct: 2727 SSMPIRIESSSSH-VAEGETLDLNC-VVPGQ-AHAQVTWHKRGGSLPSYHQTRGS----- 2778

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFG 3911
              L + +V   DSGEY+CR +   G
Sbjct: 2779 -RLRLHHVSPADSGEYVCRVMGSSG 2802



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 1/71 (1%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            GQ+  F C  + V  P + I W  N   +    R+   S+ G   L I   +  D G Y 
Sbjct: 421  GQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRVTVTSEGGRGTLIIRDVKESDQGAYT 479

Query: 3224 CRAYNKYGEDF 3234
            C A N  G  F
Sbjct: 480  CEAMNARGMVF 490



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            S   V EGQ +   C +     ++ +V W K G  +   H+   +H      L ++ +  
Sbjct: 2446 SSSQVAEGQTLDLNCLV--AGQAHAQVTWHKRGGSLPARHQ---VHGS---RLRLLQVTP 2497

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRLT 1535
             DSG Y CR V   GT E S  +T
Sbjct: 2498 ADSGEYVCRVVGSSGTQEASVLVT 2521



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 10/101 (9%)

Query: 632  RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
            RV PP +  +   S T +EG  +     +     P   I W K G S+ +  +       
Sbjct: 2629 RVSPPIR--IESSSPTVVEGQTLDLNCVV--ARQPQAIITWYKRGGSLPSRHQTHG---- 2680

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
             ++ L  +S  + DSGEY CRA +     E   V+ V+P A
Sbjct: 2681 SHLRLHQMS--VADSGEYVCRANNNIDALEASIVISVSPSA 2719



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P +I    SH V E + +   C V P +    ++ WY+ G  LP+ H+           L
Sbjct: 2928 PIYIEASSSH-VTEGQTLDLNC-VVPGQ-AHAQVTWYKRGGSLPARHQTHGS------QL 2978

Query: 3890 DILYVYAEDSGEYICRAVNDFGED 3913
             + +V   DSGEY+CRA    G +
Sbjct: 2979 RLHHVSPADSGEYVCRAAGGPGPE 3002



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 1/84 (1%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP+     +++I    G  V F C    V  P + I+W  N     +  RV   ++ G  
Sbjct: 405  PPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRVTVTSEGGRG 463

Query: 3754 ALDIDYIYARDAGEYTCRATNKWG 3777
             L I  +   D G YTC A N  G
Sbjct: 464  TLIIRDVKESDQGAYTCEAMNARG 487



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 8/108 (7%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +PP  TT P    +    +   +C  +      +  +W   G  L    R    N+    
Sbjct: 3299 SPPYATTVPEHASVQAGETVQLQC--LAHGTPPLTFQWSRVGSSL--PGRATARNE---- 3350

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663
            +L        D+G Y C+ TN+ G A    +L V+G  G +    +P+
Sbjct: 3351 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPA 3398



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 3/85 (3%)

Query: 390 LAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPE-VTWFINDRQIRDDYNHKILVNESGN 447
           + PQ V   ++    + G+   F C   G P P  + W +N   I       +  +E G 
Sbjct: 404 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTV-TSEGGR 462

Query: 448 HALMITNVTLSDSGVVTCVARNKSG 472
             L+I +V  SD G  TC A N  G
Sbjct: 463 GTLIIRDVKESDQGAYTCEAMNARG 487



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 9/94 (9%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            S PP    +I+S +   +EG   +           ++ WYR G  LP    +  V+    
Sbjct: 2051 SQPP---VKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLP---HHTQVHGS-- 2102

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              L +  V   DSGEY+CR  N  G      T+S
Sbjct: 2103 -RLRLPQVSPADSGEYVCRVENGSGPKEASITVS 2135



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+   +R +T+     
Sbjct: 2153 TRPIRIEPSSSH--VAEGQTLDLNCVVP--GQAHAQVTWHKRGGSLP--ARHQTHGSL-- 2204

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +   T AD+GEY    V   G    S +V +
Sbjct: 2205 --LRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2237



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 10/100 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P++++  S+   V+EG+ + L C +   G    +V W+  G S+   +R +T+     
Sbjct: 2926 AQPIYIEASSSH--VTEGQTLDLNCVVP--GQAHAQVTWYKRGGSLP--ARHQTHGS--- 2976

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
              L + H + AD+GEY  RA    G    ++    +  S+
Sbjct: 2977 -QLRLHHVSPADSGEYVCRAAGGPGPEQEASFTVTVPPSE 3015



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 31/101 (30%), Positives = 43/101 (42%), Gaps = 5/101 (4%)

Query: 3817 SDAP-KEEPIVSTPPKFITQIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLP 3873
            SD P + +     PP+ +T  +  +++ S G  V F C       P L I W  N   +P
Sbjct: 392  SDCPDRSDEFGCMPPQVVTPPRE-SIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIP 449

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDF 3914
            S  R     + G  +L I  V   D G Y C A+N  G  F
Sbjct: 450  SQPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVF 490



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 1/83 (1%)

Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
           P+  TP ++ I    G    F      +    L + W  +   + +  R+T     G   
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPAPFL-INWRLNWGHIPSQPRVTVTSEGGRGT 464

Query: 969 LTIKSVTVHDAGHYTCRAYNAIG 991
           L I+ V   D G YTC A NA G
Sbjct: 465 LIIRDVKESDQGAYTCEAMNARG 487



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/55 (36%), Positives = 25/55 (45%)

Query: 4090 MEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            M A  Q T    V+ S     PV    P  +TV+ G+ A F C  TG P P + W
Sbjct: 1847 MFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1901



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            ++P+ ++P S+   V+EG+ + L C +   G    +V W   G S+ V  R +T+     
Sbjct: 2342 TQPIRIEPSSSQ--VAEGQTLDLNCVVP--GQSHAQVTWHKRGGSLPV--RHQTHGSL-- 2393

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L +  A+ AD+GEY  R +        S +V +
Sbjct: 2394 --LRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2426



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 10/95 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            S P+ ++  S+   V+EG+ + L C +   G    +V W   G S+       +Y+    
Sbjct: 2728 SMPIRIE--SSSSHVAEGETLDLNCVVP--GQAHAQVTWHKRGGSLP------SYHQTRG 2777

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              L + H + AD+GEY  R +   G    S +V +
Sbjct: 2778 SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI 2812



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 3695 PRFTVEIKDNID-VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            P   + I+ ++  V  G  V F+C    +GDP  ++ W   G     G     +   G +
Sbjct: 3489 PSVLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVV 3542

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL--ESQLPQG 3802
               I ++   DAG+Y C ATN  G+  +   +   A   I +  E ++P G
Sbjct: 3543 R--IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAG 3591



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 10/123 (8%)

Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVAL 2169
            V +   TS++ +  G    FEC    + DP   + W   G  +R G         G V  
Sbjct: 3491 VLINIRTSVQTVVVGHAVEFECLA--LGDPKPQVTWSKVGGHLRPG----IVQSGGVVR- 3543

Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIIL--DTQHPNGLEKIRQLEAQG 2227
             I +    D+G Y C ATN  G   +   L V     I +  + + P G   +    A G
Sbjct: 3544 -IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCIASG 3602

Query: 2228 HST 2230
            + T
Sbjct: 3603 YPT 3605



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 12/80 (15%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP--IHDFGYVALDIIDL 1509
            S++ V+ G  V FEC    + D   +V W K G     GH  RP  +   G V +  ++L
Sbjct: 3498 SVQTVVVGHAVEFECLA--LGDPKPQVTWSKVG-----GH-LRPGIVQSGGVVRIAHVEL 3549

Query: 1510 IAEDSGIYTCRAVNLVGTDE 1529
               D+G Y C A N  GT +
Sbjct: 3550 A--DAGQYRCTATNAAGTTQ 3567



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 9/100 (9%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++   P  +MP +++RV    AA F    I  G P   + W +    +   +RL      
Sbjct: 3573 LVQALPQISMP-QEVRVPAGSAAVFPC--IASGYPTPDISWSKLDGSLPPDSRLENN--- 3626

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                L +  V P+D+GTY C A N  G+    + L V  +
Sbjct: 3627 ---MLMLPSVQPQDAGTYVCTATNRQGKVKAFAHLQVPER 3663


>M32292-1|AAA35751.1|  750|Homo sapiens protein ( Human colorectal
            tumor suppressor mRNA (DCC), 5' end. ).
          Length = 750

 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 89/378 (23%), Positives = 159/378 (42%), Gaps = 35/378 (9%)

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
            +P+IKW ++   +    D +    S  S+LI        + + +   +   G  +C A+L
Sbjct: 69   VPVIKWKKDGIHLALGMDERKQQLSNGSLLI-------QNILHSRHHKPDEGLYQCEASL 121

Query: 4499 -----VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++    +    G  P  F    ++V    G  V L  +V G     ++W KN + 
Sbjct: 122  GDSGSIISRTAKVAVAG--PLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQD 179

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P   +  +    +  L I    P D G Y C A N A  +R   E  V + +     +
Sbjct: 180  LTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPAS-SRTGNEAEVRILSDPGLHR 238

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK-PSKYFQMS 4672
             Q      P  ++         EG+     C + G P P+  W +G+++I+  SK + + 
Sbjct: 239  -QLYFLQRPSNVV-------AIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLL 290

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
              ++   L IS    +D G Y CV       ++ +A+L V  P    N P+     ++  
Sbjct: 291  GGSN---LLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPS-----NLYA 342

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
            YE    +F+  ++ K  PT+ W++ G ++  +  FQ++   N  +L      + D G + 
Sbjct: 343  YESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL---GVVKSDEGFYQ 399

Query: 4793 CRATTAAGQVETSAKLVV 4810
            C A   AG  +TSA+L+V
Sbjct: 400  CVAENEAGNAQTSAQLIV 417



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 88/338 (26%), Positives = 130/338 (38%), Gaps = 30/338 (8%)

Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
            ++T +  V GP++      F  + +    F  +    + E  GEP+P I W +    +  
Sbjct: 129  SRTAKVAVAGPLR------FLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTP 182

Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513
             P            L I ++   D  ++   A N    A        E +     G    
Sbjct: 183  IPGDSRVVVLPSGALQISRLQPGDIGIYRCSARN---PASSRTGNEAEVRILSDPGLHRQ 239

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
              F     NV    G+   L+  V+G  P    WL+  + +Q  +R+K     G   LLI
Sbjct: 240  LYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQ--LRSKKYSLLGGSNLLI 297

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
                  DSG Y CV           AE  V +P                P  +    +  
Sbjct: 298  SNVTDDDSGMYTCVVTYKNENISASAELTVLVP----------------PWFLNHPSNLY 341

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
              E   IEF C + GKP+PTV W K   ++ PS YFQ+   ++   LRI      DEG Y
Sbjct: 342  AYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSN---LRILGVVKSDEGFY 398

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
            +CVA N AG    +A+L V +P    +    +  RD+V
Sbjct: 399  QCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVV 436



 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 66/203 (32%), Positives = 93/203 (45%), Gaps = 14/203 (6%)

Query: 378 ETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
           E E RI +S+  L  Q   + +  +V   EGK    +C V+G P P  TW   +  I+  
Sbjct: 225 EAEVRI-LSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLR 283

Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
                L+   G   L+I+NVT  DSG+ TCV   K+   +    L V+     V P F+ 
Sbjct: 284 SKKYSLL---GGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVL-----VPPWFLN 335

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
             S L   E   +       G P P + W K+G  +IP+   +I    G S L I     
Sbjct: 336 HPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVK 392

Query: 556 SDAAWYQCTAQNVAGSTATRARL 578
           SD  +YQC A+N AG+  T A+L
Sbjct: 393 SDEGFYQCVAENEAGNAQTSAQL 415



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 36/94 (38%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP     P N    E  D +F+  +SG P P V W KNG  +I S+  +I+   N   LR
Sbjct: 330 PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSN---LR 386

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           +    KSD G Y  +AEN  G   TS  L V  P
Sbjct: 387 ILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKP 420



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 6/117 (5%)

Query: 625 IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
           I    E  V  PP F+    ++ A E   I FE  +   G P   + W+KNG  +  S  
Sbjct: 319 ISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDVVIPSDY 376

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
           F  +   G  +L +L +   D G Y C A +  G A+T A L + P+  I  +S  P
Sbjct: 377 FQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL-IVPKPAIPSSSVLP 429



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 10/157 (6%)

Query: 4348 PDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTE----TTEIEHKAQTQERVVEG 4403
            P PS + + G+EV   + K+    + G   +   +T  +    T  + +K +      E 
Sbjct: 267  PPPSFTWLRGEEVIQLRSKKYSL-LGGSNLLISNVTDDDSGMYTCVVTYKNENISASAEL 325

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
             V    PP F         +E     FE    G+P+P + W +    +  S  FQI   S
Sbjct: 326  TVLV--PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGS 383

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
               IL    V   D   +  VAEN  G A+ SA L+V
Sbjct: 384  NLRIL---GVVKSDEGFYQCVAENEAGNAQTSAQLIV 417



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 46/189 (24%), Positives = 76/189 (40%), Gaps = 15/189 (7%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           A +F+    D     G     DC   + R  P + W  +   +    + +    +  N +
Sbjct: 39  ALRFLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDER--KQQLSNGS 96

Query: 450 LMITNVTLS-----DSGVVTCVAR-NKSGETAFQCRLNVIEKEQVVAP-KFVERFSTLNV 502
           L+I N+  S     D G+  C A    SG       ++   K  V  P +F+ +  ++  
Sbjct: 97  LLIQNILHSRHHKPDEGLYQCEASLGDSGSI-----ISRTAKVAVAGPLRFLSQTESVTA 151

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             G+ V+L    +G P P I WQK+   + P P         +  L I R +  D   Y+
Sbjct: 152 FMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYR 211

Query: 563 CTAQNVAGS 571
           C+A+N A S
Sbjct: 212 CSARNPASS 220



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 7/115 (6%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E  V  PP F+    +    ES  + FEC V  K  P   + W +NG ++     ++ V 
Sbjct: 324  ELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVP--TVNWMKNGDVVIPSDYFQIV- 380

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK--LPDIILQNQVPR 3935
              G  +L IL V   D G Y C A N+ G   T A +   K  +P   +    PR
Sbjct: 381  --GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPR 433



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 270 QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEIITTHNHTTLRVRNT 328
           Q+P N    EG DA  +  +SG P P  TW +  + + + S K+ ++   N   L + N 
Sbjct: 244 QRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSN---LLISNV 300

Query: 329 QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
              DSG YT +    N  I  S  L V  P
Sbjct: 301 TDDDSGMYTCVVTYKNENISASAELTVLVP 330



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/73 (36%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 411 FDCRVTGRPYPEVTWFIN-DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
           F+C V+G+P P V W  N D  I  DY   +     G   L I  V  SD G   CVA N
Sbjct: 350 FECTVSGKPVPTVNWMKNGDVVIPSDYFQIV-----GGSNLRILGVVKSDEGFYQCVAEN 404

Query: 470 KSGETAFQCRLNV 482
           ++G      +L V
Sbjct: 405 EAGNAQTSAQLIV 417



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 6/127 (4%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++TV+  P F     N+   E  ++  EC +   G     V W  NG  +     F+   
Sbjct: 324  ELTVLVPPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDVVIPSDYFQIVG 381

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQY 1423
              +   L +L V   D G Y C A N+ G A TS  L ++ K  +   S  PS    +  
Sbjct: 382  GSN---LRILGVVKSDEGFYQCVAENEAGNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVP 437

Query: 1424 LEDTSRY 1430
            +  +SR+
Sbjct: 438  VLVSSRF 444



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 5/93 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   PS+L   E+    FEC +         V W  NG  ++     + +      I
Sbjct: 330  PPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRI 387

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L   GV + D G Y C A N  G A  S +L V
Sbjct: 388  L---GVVKSDEGFYQCVAENEAGNAQTSAQLIV 417



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 5/88 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++H +N+   E  +I FEC V     PT  + W  N   +     ++     +   L I
Sbjct: 333  FLNHPSNLYAYESMDIEFECTVSGKPVPT--VNWMKNGDVVIPSDYFQIVGGSN---LRI 387

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                + D G Y C A N  G+A TS  L
Sbjct: 388  LGVVKSDEGFYQCVAENEAGNAQTSAQL 415



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 10/98 (10%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            +V + P F+  P ++    E   + FEC +  +PV   N    W KNG  V     F+ +
Sbjct: 326  TVLVPPWFLNHPSNLY-AYESMDIEFECTVSGKPVPTVN----WMKNGDVVIPSDYFQIV 380

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
               G   L I+ ++  D G Y C A N  G  + S +L
Sbjct: 381  ---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL 415



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 7/140 (5%)

Query: 1694 TSKYQRHSAQDEV-ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVP 1752
            T K +  SA  E+ +   P F     ++   E+    FE  +   G P   V W++NG  
Sbjct: 313  TYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDV 370

Query: 1753 IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
            +  S+    +   G   L +  V   D G Y C A NE G A TS+ L V  K ++   S
Sbjct: 371  VIPSDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIV-PKPAIPSSS 426

Query: 1813 QHESALQKIQQLEDSSRYQR 1832
               SA + +  +  SSR+ R
Sbjct: 427  VLPSAPRDVVPVLVSSRFVR 446



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 8/119 (6%)

Query: 1850 LNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL 1907
            LN P+ L   E     +EC +   P P   V W  NG V+     ++     G + L IL
Sbjct: 334  LNHPSNLYAYESMDIEFECTVSGKPVPT--VNWMKNGDVVIPSDYFQI---VGGSNLRIL 388

Query: 1908 TVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKR 1966
             V   D G Y C A N  G A +S +L +  K +I   S   SA   +  +   SR+ R
Sbjct: 389  GVVKSDEGFYQCVAENEAGNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVPVLVSSRFVR 446



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F     N    +  + +FE  + G P P V+W +    ++  +     Y +  G  +
Sbjct: 330 PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSD-----YFQIVGGSN 384

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L I  +   DEG Y C A N+ G A  S  +
Sbjct: 385 LRILGVVKSDEGFYQCVAENEAGNAQTSAQL 415



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 2367 IPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT 2426
            + +P   ++  F Q   N+  I EG+ A  +C +   G P     W R E++I+  S+  
Sbjct: 231  LSDPGLHRQLYFLQRPSNVVAI-EGKDAVLECCVS--GYPPPSFTWLRGEEVIQLRSK-- 285

Query: 2427 KTHDFGYVSMTISHVRDEDEGVYMC 2451
            K    G  ++ IS+V D+D G+Y C
Sbjct: 286  KYSLLGGSNLLISNVTDDDSGMYTC 310



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 7/103 (6%)

Query: 1167 YQIEEISKSKP--VFVQP--LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            Y+ E IS S    V V P  L++P  +   +++ +E      G P   V W  NG  V  
Sbjct: 314  YKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIP 373

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
               F+     G   L I+    +D G Y   A N  G+A TSA
Sbjct: 374  SDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSA 413



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 15/50 (30%), Positives = 26/50 (52%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            PP F++ P  +   E     F C V+G P P V W+ NG+ ++    +++
Sbjct: 330  PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQI 379



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P W +   +     E   +  E  V  K  P   + W  NG V+     F++    G   
Sbjct: 330  PPWFLNHPSNLYAYESMDIEFECTVSGKPVPT--VNWMKNGDVVIPSDYFQIV---GGSN 384

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            L ++ V + D G Y C A N+ G A TS+
Sbjct: 385  LRILGVVKSDEGFYQCVAENEAGNAQTSA 413



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 4/87 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W+K+G  V  S     F   G   L I  V   D G Y C A N  G A TSA L IV
Sbjct: 362  VNWMKNGDVVIPSDY---FQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL-IV 417

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRY 1029
             K  I + S  P     +  +  +SR+
Sbjct: 418  PKPAIPSSSVLPSAPRDVVPVLVSSRF 444



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/117 (25%), Positives = 46/117 (39%), Gaps = 9/117 (7%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNK---PLPSGTRYKSTHDFSYVS 2832
            F+S   ++    GD +  +C V     PT  I W  N +   P+P  +R       +   
Sbjct: 142  FLSQTESVTAFMGDTVLLKCEVIGEPMPT--IHWQKNQQDLTPIPGDSRVVVLPSGA--- 196

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSAT-TSGSLRCTGDKNIYFDTQHPQGKAGLEAVE 2888
            L I+     D GIY C A N   S T     +R   D  ++      Q  + + A+E
Sbjct: 197  LQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIE 253



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            +G     + W  NG  +  S   + V   G   L ILG   +D G Y C A N+ G A+ 
Sbjct: 355  SGKPVPTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQT 411

Query: 3135 SVKL 3138
            S +L
Sbjct: 412  SAQL 415


>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
          Length = 1248

 Score = 93.5 bits (222), Expect = 2e-17
 Identities = 105/385 (27%), Positives = 164/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 262  EGFPTPTIKWLRPSGPMPADRATYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 317

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 318  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 367

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 368  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 425

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 426  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 470

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKVT   Q    P     R 
Sbjct: 471  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVTDATQITQGP-----RS 521

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 522  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 578

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 579  SDQGNYSCVASTELDVVESRAQLLV 603



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 327 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 384

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 385 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 441

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 442 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 498

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 499 NNVTIMANL 507



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 79/306 (25%), Positives = 118/306 (38%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   +   ++   TL +L+ 
Sbjct: 241  TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RATYQNHNKTLQLLKV 297

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 298  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 341

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 342  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 396

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 397  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 450

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 451  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 507

Query: 4809 VVKSKT 4814
             V   T
Sbjct: 508  KVTDAT 513



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 339 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 395

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 396 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 448

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 449 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 505

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 506 NLKVTDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 565

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 566 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 603



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 76/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 343  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 401

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 402  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 451

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 452  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANLK 508

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
            V+           T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 509  VT---------DATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 551

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 552  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 603



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 50/191 (26%), Positives = 77/191 (40%), Gaps = 15/191 (7%)

Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           AP++ K   +  +V EG+     C       P   +++N + +    + ++ + ++GN  
Sbjct: 130 APKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGN-- 187

Query: 450 LMITNVTLSDS-GVVTCVARNKSGETAFQCR---LNVIEKEQVVAPKFVERFST-----L 500
           L   NV  SD+     C A      T  Q     L V     ++  K    F T     L
Sbjct: 188 LYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHL 247

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +G+P+VL   A G PTP I W +   P  P P  R        TL + +    D   
Sbjct: 248 VALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRATYQNHNKTLQLLKVGEEDDGE 304

Query: 561 YQCTAQNVAGS 571
           Y+C A+N  GS
Sbjct: 305 YRCLAENSLGS 315



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 328 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 383

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 384 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 440

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 441 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 493

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ ++D+  +T   R+    K     F C+
Sbjct: 494 AANDQNNVTIMANLKVTDATQITQGPRSTIEKKGSRVTFTCQ 535



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 251 QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRATYQNHNKTLQLLKVGEEDDGEY 305

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 306 RCLAENSLGSARHAYYVTVE 325



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+    ++T+     +L +    E
Sbjct: 245  SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPAD---RATYQNHNKTLQLLKVGE 299

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 300  EDDGEYRCLAENSLGSA 316



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 231  IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRATYQNH 288

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 289  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 326



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 435 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 487

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 488 GRYFCLAANDQNNVTIMANLKVTDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 541

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 542 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 598

Query: 576 ARL 578
           A+L
Sbjct: 599 AQL 601



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 33/127 (25%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 206  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 262

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P       +  ++     L +  +   D GEY C A N  GSA   
Sbjct: 263  GFPTPTIKWLRPSGPMPADRATYQNHNK---TLQLLKVGEEDDGEYRCLAENSLGSARHA 319

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 320  YYVTVEA 326



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 39/138 (28%), Positives = 56/138 (40%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 194  LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 250

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R  TY +     L +  V  ED G Y  
Sbjct: 251  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRA-TYQNHNKT-LQLLKVGEEDDGEYRC 307

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 308  LAENSLGSARHAYYVTVE 325



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 322  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 378

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 379  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 428



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 328  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 365



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 246  HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RATYQNHNKTLQLLKVGEE 300

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 301  DDGEYRCLAENSLGSA 316



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 36/97 (37%), Gaps = 4/97 (4%)

Query: 1699 RHSAQDEVITQAPVFTMPMKDI-RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN 1757
            R  A + +I + P    P      +   Q        I  G P   ++WLR   P+ A  
Sbjct: 223  RVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADR 282

Query: 1758 RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
                 H+     L +  V  ED G Y C A N LG A
Sbjct: 283  ATYQNHN---KTLQLLKVGEEDDGEYRCLAENSLGSA 316



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 6/99 (6%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            +F T+  S+   ++GQ + LE   E    P +K  W +    +      ++T+     TL
Sbjct: 238  LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPAD---RATYQNHNKTL 292

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR-HWL 2740
             +  +  +D G Y C A N LG A     + +E   +WL
Sbjct: 293  QLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWL 331



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 239  FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RATYQNHNKTLQ 293

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 294  LLKVGEEDDGEYRCLAENSLG 314


>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
          Length = 1461

 Score = 93.1 bits (221), Expect = 2e-17
 Identities = 83/321 (25%), Positives = 133/321 (41%), Gaps = 26/321 (8%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT + +P  V+    A    E + + +P ++W +   P+    D  I   S   +L+I
Sbjct: 152  PRFTSQPEPSSVYAGNGAILNCEVNADLVPFVRWEQNRQPLLLD-DRVIKLPS--GMLVI 208

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                  D  ++  V E+ GG  K S    VE K       I    F      +    GQ 
Sbjct: 209  SNATEGDGGLYRCVVES-GGPPKYSDE--VELKVLPDPEVISDLVFLKQPSPLVRVIGQD 265

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            V L    +G     + W+KN + +  +   +++   G  +L I +    D+G Y C+A N
Sbjct: 266  VVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADN 324

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
                    AE  V                 A PE ++   +    E   I F C++ GKP
Sbjct: 325  GNETIEAQAELTVQ----------------AQPEFLKQPTNIYAHESMDIVFECEVTGKP 368

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             PTV+W K   ++ PS YF++ +   E+ L++      DEG Y+C+A N  G     A+L
Sbjct: 369  TPTVKWVKNGDMVIPSDYFKIVK---EHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQL 425

Query: 4711 KVTQPDQADNLPALTPLRDIV 4731
             + +   A   P  +  RD+V
Sbjct: 426  IILEHAPATTGPLPSAPRDVV 446



 Score = 86.2 bits (204), Expect = 3e-15
 Identities = 97/380 (25%), Positives = 161/380 (42%), Gaps = 37/380 (9%)

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE----DSAVFAAVA--ENRGG 4490
            EP P I+W ++   +    D +       S+ I   V  +    D   +  VA  E+ G 
Sbjct: 79   EPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGT 138

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKN 4550
                +A L+V         G+  P FT   +  +V +G    L+ +V       V W +N
Sbjct: 139  IISRTAKLIV--------AGL--PRFTSQPEPSSVYAGNGAILNCEVNADLVPFVRWEQN 188

Query: 4551 GKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
             + +  D R   L       L+I  A   D G Y CV + S G  +   E  V L   K 
Sbjct: 189  RQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCV-VESGGPPKYSDE--VEL---KV 239

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
             P P+  +     +   PL   I   GQ +   C   G P PT++W K ++ +      +
Sbjct: 240  LPDPEVISDLVFLKQPSPLVRVI---GQDVVLPCVASGLPTPTIKWMKNEEALDTESSER 296

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +   A   +L IS+   +D G Y C+A N  G  T+ A+ ++T   Q + L   T   +I
Sbjct: 297  LVLLAGG-SLEISDVTEDDAGTYFCIADN--GNETIEAQAELTVQAQPEFLKQPT---NI 350

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
              +E     F+ ++T K  PT++W++ G ++  +  F+++ E N  VL      + D G 
Sbjct: 351  YAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVL---GLVKSDEGF 407

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C A    G  +  A+L++
Sbjct: 408  YQCIAENDVGNAQAGAQLII 427



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 44/166 (26%), Positives = 80/166 (48%), Gaps = 10/166 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  +G P P + W  N+  +  + + ++++   G+  L I++VT  D+G   C+A N + 
Sbjct: 270 CVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTEDDAGTYFCIADNGNE 327

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
               Q  L V  +     P+F+++ + +   E   +V      G PTP + W K+G  +I
Sbjct: 328 TIEAQAELTVQAQ-----PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVI 382

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           P+   +I  +     L + +   SD  +YQC A+N  G+    A+L
Sbjct: 383 PSDYFKIVKEHNLQVLGLVK---SDEGFYQCIAENDVGNAQAGAQL 425



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
           E    L   + P+  ++P N    E  D  F+ +++G P P V W KNG  +I S+  +I
Sbjct: 330 EAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKI 389

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           +  HN   L+V    KSD G Y  +AEN  G
Sbjct: 390 VKEHN---LQVLGLVKSDEGFYQCIAENDVG 417



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 52/189 (27%), Positives = 81/189 (42%), Gaps = 7/189 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+F    +   V  G     +C V     P V W  N + +  D   +++   SG   L+
Sbjct: 152 PRFTSQPEPSSVYAGNGAILNCEVNADLVPFVRWEQNRQPLLLD--DRVIKLPSG--MLV 207

Query: 452 ITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPK-FVERFSTLNVREGEPVV 509
           I+N T  D G+  CV  +    + + +  L V+   +V++   F+++ S L    G+ VV
Sbjct: 208 ISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVV 267

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L   A G PTP I W K+   +      R+    G S L+I      DA  Y C A N  
Sbjct: 268 LPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS-LEISDVTEDDAGTYFCIADNGN 326

Query: 570 GSTATRARL 578
            +   +A L
Sbjct: 327 ETIEAQAEL 335



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 44/141 (31%), Positives = 62/141 (43%), Gaps = 13/141 (9%)

Query: 347 IVTSGYLAVESPTESYVQDQRSQY--ITDTQQRETEERIEISEKALAPQFVKVCQDRDVT 404
           ++  G L +   TE    D    Y  I D      E + E++ +A  P+F+K   +    
Sbjct: 299 LLAGGSLEISDVTE----DDAGTYFCIADNGNETIEAQAELTVQA-QPEFLKQPTNIYAH 353

Query: 405 EGKMTRFDCRVTGRPYPEVTWFIN-DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV 463
           E     F+C VTG+P P V W  N D  I  DY  KI V E   H L +  +  SD G  
Sbjct: 354 ESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDY-FKI-VKE---HNLQVLGLVKSDEGFY 408

Query: 464 TCVARNKSGETAFQCRLNVIE 484
            C+A N  G      +L ++E
Sbjct: 409 QCIAENDVGNAQAGAQLIILE 429



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 66/280 (23%), Positives = 118/280 (42%), Gaps = 34/280 (12%)

Query: 4545 VYWLKNGK--KVQPDIRNKILEEDGTYTLLILEAYPQ--DSGKYECVA-INSAGE--ARC 4597
            + W K+G    +  D R ++L +   +   ++ +     D G Y+CVA + S G   +R 
Sbjct: 84   IEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRT 143

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
                V  LP    +P+P +                 V  G     +C++    +P V+W 
Sbjct: 144  AKLIVAGLPRFTSQPEPSS-----------------VYAGNGAILNCEVNADLVPFVRWE 186

Query: 4658 KGDK-LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG-RVTVAAKLKVT-Q 4714
            +  + L+   +  ++        L IS A   D G Y+CV  +    + +   +LKV   
Sbjct: 187  QNRQPLLLDDRVIKLPSGM----LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPD 242

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGALIPETPDFQMIHEG 4773
            P+   +L  L     +V   GQ        +    PTI+W++ E AL  E+ +  ++  G
Sbjct: 243  PEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAG 302

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +  L I +  E+D GT+ C A      +E  A+L V+++
Sbjct: 303  GS--LEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ 340



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 5/113 (4%)

Query: 1291 LEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            + D    T + + ++TV   P+F +   NI   E  ++  EC +   G  T  V+W  NG
Sbjct: 321  IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNG 378

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
              +     F+   E +   L +L +   D G Y C A N +G A     L ++
Sbjct: 379  DMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIIL 428



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 45/159 (28%), Positives = 62/159 (38%), Gaps = 12/159 (7%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            + +G  +  I+W  N + ++     R V   G   LEI      D+GTY C A N  G  
Sbjct: 271  VASGLPTPTIKWMKNEEALDTESSERLVLLAGGS-LEISDVTEDDAGTYFCIADN--GNE 327

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
             I  + E   ++   +P F     NI    +     FEC V     P +K  W  NG  +
Sbjct: 328  TIEAQAELTVQA---QPEFLKQPTNIYA-HESMDIVFECEVTGKPTPTVK--WVKNGDMV 381

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              S   K V +    VL +      D G Y C A N  G
Sbjct: 382  IPSDYFKIVKEHNLQVLGLV---KSDEGFYQCIAENDVG 417



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 5/76 (6%)

Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG--VPIIPNPELRIHTDGGASTLDIP 551
           VE   TL+VR G  V+LN  A   P+P+I W+KDG  + ++ +   ++  DG     ++ 
Sbjct: 57  VEPVDTLSVR-GSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVV 115

Query: 552 RAKAS--DAAWYQCTA 565
            +K +  D  +YQC A
Sbjct: 116 HSKHNKPDEGYYQCVA 131



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            + G  +   + E  V   P+F+ Q  +    ES  + FEC V  K  P   ++W +NG +
Sbjct: 323  DNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTP--TVKWVKNGDM 380

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            +     ++ V +    +L +L +   D G Y C A ND G
Sbjct: 381  VIPSDYFKIVKEH---NLQVLGLVKSDEGFYQCIAENDVG 417



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 6/96 (6%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V  +P F+ +P +I    E   + FEC++       +K  W KNG  V     F+ + +
Sbjct: 336  TVQAQPEFLKQPTNIY-AHESMDIVFECEVTGKPTPTVK--WVKNGDMVIPSDYFKIVKE 392

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                 L ++ L+  D G Y C A N VG  +   +L
Sbjct: 393  HN---LQVLGLVKSDEGFYQCIAENDVGNAQAGAQL 425



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 5/100 (5%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
           V   P+F+    ++ A E   I FE  +   G PT  ++W+KNG  +  S  F  +    
Sbjct: 337 VQAQPEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFKIVKEH- 393

Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
             +L +L L   D G Y C A +  G A+  A L +   A
Sbjct: 394 --NLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHA 431



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            PEF   P+++   E+    FEC +      +  V+W  NG  ++     K + +    +L
Sbjct: 341  PEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVL 398

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
               G+ + D G Y C A N  G A    +L
Sbjct: 399  ---GLVKSDEGFYQCIAENDVGNAQAGAQL 425



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/112 (23%), Positives = 44/112 (39%), Gaps = 2/112 (1%)

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            E   +  P F+  P  +   E     F C VTG P P V W+ NG+ ++    +K+  + 
Sbjct: 334  ELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKE- 392

Query: 4164 MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPR 4215
             ++  +    + D G  + I             L ++       G L +APR
Sbjct: 393  -HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPR 443



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 44/176 (25%), Positives = 76/176 (43%), Gaps = 17/176 (9%)

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK--PSKYFQMSRTADEYTLRI 4682
            ++EP+ D +   G ++  +C    +P P ++W K    +        Q+      +   +
Sbjct: 56   LVEPV-DTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNV 114

Query: 4683 --SEAFPEDEGDYKCVA-YNSAGR-VTVAAKLKVTQPDQADNLPALTPLRD-IVVYEGQP 4737
              S+    DEG Y+CVA   S G  ++  AKL V        LP  T   +   VY G  
Sbjct: 115  VHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVA------GLPRFTSQPEPSSVYAGNG 168

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            A    ++ + + P ++W  E    P   D ++I +  + +L+I N  E D G + C
Sbjct: 169  AILNCEVNADLVPFVRW--EQNRQPLLLDDRVI-KLPSGMLVISNATEGDGGLYRC 221



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)

Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            Q E   +++P F++  +N     E  +I  EC  E  G PT  V+W  NG  V     FK
Sbjct: 332  QAELTVQAQPEFLKQPTNIY-AHESMDIVFEC--EVTGKPTPTVKWVKNGDMVIPSDYFK 388

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT 1277
               +     L ++    +D G Y   A N +G+A   A + ++E +   T
Sbjct: 389  IVKEHN---LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATT 435



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 33/141 (23%), Positives = 57/141 (40%), Gaps = 10/141 (7%)

Query: 1796 TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTK 1855
            +S  L + +  SL++    E        + D+         E+ V   P F+ Q   PT 
Sbjct: 293  SSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQ---PTN 349

Query: 1856 L--SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
            +   E     +EC +   P P   V+W  NG ++     ++   +     L +L +   D
Sbjct: 350  IYAHESMDIVFECEVTGKPTPT--VKWVKNGDMVIPSDYFKIVKEHN---LQVLGLVKSD 404

Query: 1914 SGEYTCKAINNLGQAVSSIRL 1934
             G Y C A N++G A +  +L
Sbjct: 405  EGFYQCIAENDVGNAQAGAQL 425



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 1/81 (1%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
           G D       SG P P + W KN + L   +   ++      +L + +  + D+G Y  +
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAG-GSLEISDVTEDDAGTYFCI 321

Query: 340 AENPNGCIVTSGYLAVESPTE 360
           A+N N  I     L V++  E
Sbjct: 322 ADNGNETIEAQAELTVQAQPE 342



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 5/88 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+    NI   E  +I FEC V     PT+K  W  N   +     +K   +    +L +
Sbjct: 343  FLKQPTNIYAHESMDIVFECEVTGKPTPTVK--WVKNGDMVIPSDYFKIVKEH---NLQV 397

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                + D G Y C A N  G+A     L
Sbjct: 398  LGLVKSDEGFYQCIAENDVGNAQAGAQL 425



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 5/65 (7%)

Query: 91  FEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARN 150
           FE ++ G PTP V W  K   +V  + Y     E    V  L+K     DEG Y C A N
Sbjct: 360 FECEVTGKPTPTVKWV-KNGDMVIPSDYFKIVKEHNLQVLGLVK----SDEGFYQCIAEN 414

Query: 151 QYGEA 155
             G A
Sbjct: 415 DVGNA 419



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 5/104 (4%)

Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNG 2017
            + D+       Q +  V  +P+F K   N    E   +  E  +T    PT  V+W  NG
Sbjct: 321  IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVT--GKPTPTVKWVKNG 378

Query: 2018 RPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEA 2061
              V     FK   +     L +L     D G Y C A N VG A
Sbjct: 379  DMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVGNA 419



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/106 (27%), Positives = 45/106 (42%), Gaps = 6/106 (5%)

Query: 1702 AQDEVITQA-PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            AQ E+  QA P F     +I   E+    FE  +   G P   V+W++NG  +  S+   
Sbjct: 331  AQAELTVQAQPEFLKQPTNIYAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFK 388

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             + +     L +      D G Y C A N++G A   + L +   A
Sbjct: 389  IVKEHNLQVLGLV---KSDEGFYQCIAENDVGNAQAGAQLIILEHA 431



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 29/113 (25%), Positives = 50/113 (44%), Gaps = 4/113 (3%)

Query: 1446 FVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALD 1505
            F+ +P  +  VI GQ V   C    +    +K  W KN + +      R +   G  +L+
Sbjct: 251  FLKQPSPLVRVI-GQDVVLPCVASGLPTPTIK--WMKNEEALDTESSERLVLLAGG-SLE 306

Query: 1506 IIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVL 1558
            I D+  +D+G Y C A N   T E    LT ++  + ++   N    E + ++
Sbjct: 307  ISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV 359



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 10/92 (10%)

Query: 2369 EPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI--EDSSRIT 2426
            E   + +P F +   NI    E     F+C +   G PT  V+W +N  ++   D  +I 
Sbjct: 334  ELTVQAQPEFLKQPTNI-YAHESMDIVFECEV--TGKPTPTVKWVKNGDMVIPSDYFKIV 390

Query: 2427 KTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            K H+   + +  S     DEG Y C A N +G
Sbjct: 391  KEHNLQVLGLVKS-----DEGFYQCIAENDVG 417



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)

Query: 2367 IPEPVTRQRPVFT-QPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI 2425
            +P+P      VF  QP   +  I  GQ     C  +  G PT  ++W +NE+ ++  S  
Sbjct: 240  LPDPEVISDLVFLKQPSPLVRVI--GQDVVLPC--VASGLPTPTIKWMKNEEALDTESSE 295

Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
                  G  S+ IS V ++D G Y C A N
Sbjct: 296  RLVLLAGG-SLEISDVTEDDAGTYFCIADN 324



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 1/65 (1%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G PT  I+W+KN ++++  S    +   G  SL++  +   D+G Y C A +     E +
Sbjct: 274 GLPTPTIKWMKNEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADNGNETIEAQ 332

Query: 724 AVLHV 728
           A L V
Sbjct: 333 AELTV 337



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  +  ++W  NG  +  S   + V       L++LG   +D G Y C A N  G A+ 
Sbjct: 365  TGKPTPTVKWVKNGDMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVGNAQA 421

Query: 3135 SVKL 3138
              +L
Sbjct: 422  GAQL 425


>AL360004-4|CAI16954.2|  746|Homo sapiens novel protein similar to
            hemicentin (LOC392395) protein.
          Length = 746

 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 79/334 (23%), Positives = 132/334 (39%), Gaps = 41/334 (12%)

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            +   +   A +R GT +  A +VV +          PP   + A NV V+ G+   L  +
Sbjct: 453  EEGTYECTAVSRAGTGRAKAQIVVTD----------PPPQLVPAPNVTVSPGETAVLSCR 502

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V G  P ++ W+++  +V P    ++ +     +L I    P D G+Y+CVA N+ G  R
Sbjct: 503  VLGEAPYNLTWVRDW-RVLPASTGRVAQL-ADLSLEISGIIPTDGGRYQCVASNANGVTR 560

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
                 +V                   P++      +  ++G  ++ SC   G P P + W
Sbjct: 561  ASVWLLV----------------REAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISW 604

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  + ++      +     + TL I    PED G+Y C A N  G       L  T P 
Sbjct: 605  SRESQALQEDSRIHVDA---QGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPP 661

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
                + A+     ++V  G+ A    + +    P + W R G  +   P+       ++ 
Sbjct: 662  SVSAVNAV-----VLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPE-----GSSSG 711

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             L I    E D GT+TCRA    G      +L V
Sbjct: 712  KLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 745



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 65/247 (26%), Positives = 107/247 (43%), Gaps = 30/247 (12%)

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623
            +E G  +  IL A   + G YEC A++ AG  R  A+ VV                + PP
Sbjct: 437  QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVV---------------TDPPP 481

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
            +++ P  +  V+ G+    SC+++G+    + W + D  + P+   ++++ AD  +L IS
Sbjct: 482  QLV-PAPNVTVSPGETAVLSCRVLGEAPYNLTWVR-DWRVLPASTGRVAQLAD-LSLEIS 538

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
               P D G Y+CVA N+ G    +  L V +  Q         +     +  Q  + K  
Sbjct: 539  GIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVS-------IHTSSQHFSQGVEVKVS 591

Query: 4744 ITSKIKPT--IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             ++   PT  I W RE   + E      IH      L+I     ED G ++C+AT   G 
Sbjct: 592  CSASGYPTPHISWSRESQALQED---SRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT 648

Query: 4802 VETSAKL 4808
             + +  L
Sbjct: 649  DQETVTL 655



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 14/188 (7%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           APQ       +  ++G   +  C  +G P P ++W    + +++D   +I V+  G   L
Sbjct: 570 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED--SRIHVDAQGT--L 625

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +I  V   D+G  +C A N+ G       L   +   V A   V     + V  GE  VL
Sbjct: 626 IIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAV-----VLVAVGEEAVL 680

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P PR+ W + G+ +I  PE        +  L IP A+  DA  Y C A N  G
Sbjct: 681 VCEASGVPPPRVIWYRGGLEMILAPE-----GSSSGKLRIPAAQERDAGTYTCRAVNELG 735

Query: 571 STATRARL 578
             +   +L
Sbjct: 736 DASAEIQL 743



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 51/177 (28%), Positives = 76/177 (42%), Gaps = 11/177 (6%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V+ G+     CRV G     +TW + D ++      ++   +  + +L I+ +  +D G 
Sbjct: 491 VSPGETAVLSCRVLGEAPYNLTW-VRDWRVLPASTGRVA--QLADLSLEISGIIPTDGGR 547

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             CVA N +G T     L V E  QV      + FS     +G  V ++  A G PTP I
Sbjct: 548 YQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFS-----QGVEVKVSCSASGYPTPHI 602

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           +W ++   +    + RIH D    TL I      DA  Y C A N  G+      LY
Sbjct: 603 SWSRESQAL--QEDSRIHVD-AQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLY 656



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 46/175 (26%), Positives = 79/175 (45%), Gaps = 12/175 (6%)

Query: 4638 QAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            Q +  SC  V   LP  +Q  +G+  +   ++FQ S  +    LR S+A   +EG Y+C 
Sbjct: 405  QPLLVSCS-VHSALPFRLQLRRGEARLGEERHFQESGNSSWEILRASKA---EEGTYECT 460

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
            A + AG     A++ VT P      P L P  ++ V  G+ A    ++  +    + W+R
Sbjct: 461  AVSRAGTGRAKAQIVVTDPP-----PQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVR 515

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  ++P +     + +  +  L I      D G + C A+ A G    S  L+V+
Sbjct: 516  DWRVLPASTG--RVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVR 568



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 42/151 (27%), Positives = 64/151 (42%), Gaps = 16/151 (10%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W    + ++   RI  V A G ++++  G    D+G YSC+ATN+ G  + +V L   
Sbjct: 602  ISWSRESQALQEDSRIH-VDAQGTLIIQ--GVAPEDAGNYSCQATNEVGTDQETVTLYYT 658

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            D      P   + +  +  +  G+ A   C    V  P  ++ WY  G  M     I   
Sbjct: 659  D------PPSVSAVNAVVLVAVGEEAVLVCEASGVPPP--RVIWYRGGLEM-----ILAP 705

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                   L I   Q  D+G Y CRA N+ G+
Sbjct: 706  EGSSSGKLRIPAAQERDAGTYTCRAVNELGD 736



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 95/234 (40%), Gaps = 20/234 (8%)

Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184
           Q  D+SL I  I P D G Y C A N  G    SV++                  +H S+
Sbjct: 529 QLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWL----LVREAPQVSIHTSSQHFSQ 584

Query: 185 TVEHK-AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDD-FKVDTFEYRLLREVSFRESITK 242
            VE K +    GY T        ++++  +     D    VD     +++ V+  ++   
Sbjct: 585 GVEVKVSCSASGYPTPH------ISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDA--G 636

Query: 243 RYVGESDVQISTEIDR-SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
            Y  ++  ++ T+ +  +L    PP ++       +  G +A    + SG P PRV W++
Sbjct: 637 NYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR 696

Query: 302 NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            G  +I + +       +   LR+   Q+ D+G YT  A N  G       LAV
Sbjct: 697 GGLEMILAPEGS-----SSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 745



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/182 (24%), Positives = 72/182 (39%), Gaps = 15/182 (8%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V +S G+ A     ++  G+    + W  + + + AS     V     + LEI G   TD
Sbjct: 489  VTVSPGETAVLSCRVL--GEAPYNLTWVRDWRVLPAS--TGRVAQLADLSLEISGIIPTD 544

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             G Y C A+N  G    SV L        + P+ + H  + +    G      C+     
Sbjct: 545  GGRYQCVASNANGVTRASVWL-----LVREAPQVSIHTSS-QHFSQGVEVKVSCSASGYP 598

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
             P   I W    Q ++  +RI   +    ++  +A     D+G Y C+A N+ G D    
Sbjct: 599  TP--HISWSRESQALQEDSRIHVDAQGTLIIQGVA---PEDAGNYSCQATNEVGTDQETV 653

Query: 3238 TI 3239
            T+
Sbjct: 654  TL 655



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 7/129 (5%)

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
           ESGN +  I   + ++ G   C A +++G    + ++ V +    + P        + V 
Sbjct: 438 ESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPA-----PNVTVS 492

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            GE  VL+ R +G     +TW +D   ++P    R+      S L+I     +D   YQC
Sbjct: 493 PGETAVLSCRVLGEAPYNLTWVRDW-RVLPASTGRVAQLADLS-LEISGIIPTDGGRYQC 550

Query: 564 TAQNVAGST 572
            A N  G T
Sbjct: 551 VASNANGVT 559



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 7/108 (6%)

Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
           PPPQ +VP  +VT   G       R+  +G+    + W+++ + + AS+    + +   +
Sbjct: 479 PPPQ-LVPAPNVTVSPGETAVLSCRV--LGEAPYNLTWVRDWRVLPASTG--RVAQLADL 533

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQH 740
           SL++  +   D G Y C A +A GV      L V   P+ +I  +SQH
Sbjct: 534 SLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQH 581



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 8/84 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           F+QG   K      G PTP +SW+R+   L E ++  +   +  G  +L+I+ + P D G
Sbjct: 582 FSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHV---DAQG--TLIIQGVAPEDAG 636

Query: 143 EYTCTARNQYG---EAICSVYIQP 163
            Y+C A N+ G   E +   Y  P
Sbjct: 637 NYSCQATNEVGTDQETVTLYYTDP 660



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 39/147 (26%), Positives = 61/147 (41%), Gaps = 12/147 (8%)

Query: 3526 KGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVN 3585
            K  EGT +  A     +GT         +  PP+    P+ + +S   +A   CR++   
Sbjct: 451  KAEEGTYECTAVSR--AGTGRAKAQIVVTDPPPQLVPAPN-VTVSPGETAVLSCRVL--G 505

Query: 3586 DSSMRVEWFHNGK--PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643
            ++   + W  + +  P  TG RV  + D     LEI G+   D G Y C A+N +G    
Sbjct: 506  EAPYNLTWVRDWRVLPASTG-RVAQLADLS---LEISGIIPTDGGRYQCVASNANGVTRA 561

Query: 3644 SCKLQVKGRQGIILEPQLPSHFKSGTE 3670
            S  L V+    + +      HF  G E
Sbjct: 562  SVWLLVREAPQVSIHTS-SQHFSQGVE 587



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 16/143 (11%)

Query: 1802 VQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQA--------PRFITQLNGP 1853
            +Q  + + +++Q    +Q +   ED+  Y  +   EV  +Q         P  ++ +N  
Sbjct: 611  LQEDSRIHVDAQGTLIIQGVAP-EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAV 669

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
              ++ G+ A   C     P P  RV WY  G  +       +S       L I      D
Sbjct: 670  VLVAVGEEAVLVCEASGVPPP--RVIWYRGGLEMILAPEGSSSGK-----LRIPAAQERD 722

Query: 1914 SGEYTCKAINNLGQAVSSIRLNV 1936
            +G YTC+A+N LG A + I+L V
Sbjct: 723  AGTYTCRAVNELGDASAEIQLAV 745



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 8/114 (7%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMHD 1764
            V+T  P   +P  ++ V+  + A    R++  G+    + W+R+   + AS  R+  + D
Sbjct: 475  VVTDPPPQLVPAPNVTVSPGETAVLSCRVL--GEAPYNLTWVRDWRVLPASTGRVAQLAD 532

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS--KASLQLESQHES 1816
               ++L +  + P D G Y C A N  G    S  L V+   + S+   SQH S
Sbjct: 533  ---LSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFS 583



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 42/179 (23%), Positives = 69/179 (38%), Gaps = 17/179 (9%)

Query: 1775 VNPEDSGTYTCRAINELGEAVT---------SSTLFVQSKASLQLESQHESALQ--KIQQ 1823
            V+P ++   +CR + E    +T         +ST  V   A L LE          + Q 
Sbjct: 491  VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQC 550

Query: 1824 LEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFN 1883
            +  ++    R  V + V +AP+ ++        S+G      C    YP P+  + W   
Sbjct: 551  VASNANGVTRASVWLLVREAPQ-VSIHTSSQHFSQGVEVKVSCSASGYPTPH--ISWSRE 607

Query: 1884 GKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
             + LQ   R           L I  V  ED+G Y+C+A N +G    ++ L      S+
Sbjct: 608  SQALQEDSRIHVDAQ---GTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSV 663



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 10/123 (8%)

Query: 1693 DTSKYQRHSAQDEVITQAPVFTM----PMKDIRVAE---NQAAHFEARLIPVGDPKLRVE 1745
            D  +YQ  ++    +T+A V+ +    P   I  +    +Q    +      G P   + 
Sbjct: 544  DGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHIS 603

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            W R    ++  +R+   H      L ++ V PED+G Y+C+A NE+G    + TL+    
Sbjct: 604  WSRESQALQEDSRI---HVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDP 660

Query: 1806 ASL 1808
             S+
Sbjct: 661  PSV 663



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 5/117 (4%)

Query: 3835 QIKSHTVEE--SEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDIL 3892
            Q+  HT  +  S+GV  +        P   I W R  + L    R   V   G  +L I 
Sbjct: 572  QVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIH-VDAQG--TLIIQ 628

Query: 3893 YVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949
             V  ED+G Y C+A N+ G D    T+     P +   N V       EA+   EA+
Sbjct: 629  GVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEAS 685



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 5/88 (5%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V +APQ S    +    +G  V + C     G  T  + W    + ++   R     +
Sbjct: 565  LLVREAPQVSIHTSSQHFSQGVEVKVSCSAS--GYPTPHISWSRESQALQEDSRIHVDAQ 622

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLG 1392
               +   +  V PED+G Y+CQATN++G
Sbjct: 623  GTLI---IQGVAPEDAGNYSCQATNEVG 647



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 5/65 (7%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P  RV W R G+ +     +          L +      D+GTYTCRA+NELG+A   
Sbjct: 686  GVPPPRVIWYRGGLEM-----ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAE 740

Query: 1798 STLFV 1802
              L V
Sbjct: 741  IQLAV 745



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 5/88 (5%)

Query: 2253 HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDA 2312
            H  +G      C       P+  I +    +ALQ  +R H+       +L IQ   PEDA
Sbjct: 581  HFSQGVEVKVSCSASGYPTPH--ISWSRESQALQEDSRIHVD---AQGTLIIQGVAPEDA 635

Query: 2313 GEYSVKAINALGHCTSAISMTVTAKGSI 2340
            G YS +A N +G     +++  T   S+
Sbjct: 636  GNYSCQATNEVGTDQETVTLYYTDPPSV 663



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 5/84 (5%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            TS ++  +G      C       PH  I W    Q ++   R    H      L I    
Sbjct: 577  TSSQHFSQGVEVKVSCSASGYPTPH--ISWSRESQALQEDSRI---HVDAQGTLIIQGVA 631

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTL 2199
             ED+G Y C+ATN++G    T TL
Sbjct: 632  PEDAGNYSCQATNEVGTDQETVTL 655



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 3821 KEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            K + +V+ PP  +    + TV   E     CRV   E P   + W R+ ++LP+      
Sbjct: 471  KAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLG-EAP-YNLTWVRDWRVLPASTG--R 526

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            V  +  +SL+I  +   D G Y C A N  G       +  ++ P +
Sbjct: 527  VAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQV 573



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 7/94 (7%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +PP  +   + ++++    A   C    V     RV W+  G  ++      +       
Sbjct: 659  DPPSVSAVNAVVLVAVGEEAVLVCEASGVPPP--RVIWYRGGLEMILAPEGSSSGK---- 712

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             L I    +RDAG YTC+A N  G+A+   +L V
Sbjct: 713  -LRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 745



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 8/146 (5%)

Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHF 1597
            S+ +I+R+++ E G  +   +           +  V T  P       NV +  G+ A  
Sbjct: 442  SSWEILRASKAEEGTYECTAVSRAGTGRAKAQI--VVTDPPPQLVPAPNVTVSPGETAVL 499

Query: 1598 ERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINA 1657
              R++   +A   + W  + + L + +          ++L+I   +P D G Y C A NA
Sbjct: 500  SCRVL--GEAPYNLTWVRDWRVLPASTG--RVAQLADLSLEISGIIPTDGGRYQCVASNA 555

Query: 1658 LGEAVTSGIAIVHS--KKSIYLESQH 1681
             G    S   +V    + SI+  SQH
Sbjct: 556  NGVTRASVWLLVREAPQVSIHTSSQH 581



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            +G  V   C     G PT  I W    +     SR+H ++  G   L I  +   DAG Y
Sbjct: 584  QGVEVKVSCSAS--GYPTPHISWSRESQALQEDSRIH-VDAQG--TLIIQGVAPEDAGNY 638

Query: 3769 TCRATNKWGSATTTAKI 3785
            +C+ATN+ G+   T  +
Sbjct: 639  SCQATNEVGTDQETVTL 655



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 7/79 (8%)

Query: 2381 PLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS-RITKTHDFGYVSMTIS 2439
            P  N+  +  G+TA   CR++  G+    + W R+ +++  S+ R+ +  D   +S+ IS
Sbjct: 485  PAPNV-TVSPGETAVLSCRVL--GEAPYNLTWVRDWRVLPASTGRVAQLAD---LSLEIS 538

Query: 2440 HVRDEDEGVYMCRASNLLG 2458
             +   D G Y C ASN  G
Sbjct: 539  GIIPTDGGRYQCVASNANG 557



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 3/55 (5%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            G PT  + W R  + +++ SRI   H     ++ I  V  ED G Y C+A+N +G
Sbjct: 596  GYPTPHISWSRESQALQEDSRI---HVDAQGTLIIQGVAPEDAGNYSCQATNEVG 647



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 33/132 (25%), Positives = 54/132 (40%), Gaps = 14/132 (10%)

Query: 3109 EILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAH 3168
            EIL     + GTY C A ++ G      ++   D      P       N+  +  G++A 
Sbjct: 445  EILRASKAEEGTYECTAVSRAGTGRAKAQIVVTD-----PPPQLVPAPNVT-VSPGETAV 498

Query: 3169 FECTVVPVDDPDMKIEWYHNGQPMRHST-RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
              C V  + +    + W  + + +  ST R+  ++D    +  I  T   D G Y C A 
Sbjct: 499  LSCRV--LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPT---DGGRYQCVAS 553

Query: 3228 NKYGEDFTRATI 3239
            N  G   TRA++
Sbjct: 554  NANG--VTRASV 563



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 5/63 (7%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P  RV WY+ G  +  +   +S        L I   +  DAG+YT RAVN+LG+A +   
Sbjct: 688 PPPRVIWYRGGLEMILAPEGSSSGK-----LRIPAAQERDAGTYTCRAVNELGDASAEIQ 742

Query: 860 IRV 862
           + V
Sbjct: 743 LAV 745


>BC036524-1|AAH36524.1|  772|Homo sapiens DCC protein protein.
          Length = 772

 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 88/338 (26%), Positives = 130/338 (38%), Gaps = 30/338 (8%)

Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
            ++T +  V GP++      F  + +    F  +    + E  GEP+P I W +    +  
Sbjct: 63   SRTAKVAVAGPLR------FLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTP 116

Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513
             P            L I ++   D  ++   A N    A        E +     G    
Sbjct: 117  IPGDSRVVVLPSGALQISRLQPGDIGIYRCSARN---PASSRTGNEAEVRILSDPGLHRQ 173

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
              F     NV    G+   L+  V+G  P    WL+  + +Q  +R+K     G   LLI
Sbjct: 174  LYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQ--LRSKKYSLLGGSNLLI 231

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
                  DSG Y CV           AE  V +P                P  +    +  
Sbjct: 232  SNVTDDDSGMYTCVVTYKNENISASAELTVLVP----------------PWFLNHPSNLY 275

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
              E   IEF C + GKP+PTV W K   ++ PS YFQ+   ++   LRI      DEG Y
Sbjct: 276  AYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSN---LRILGVVKSDEGFY 332

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
            +CVA N AG    +A+L V +P    +    +  RD+V
Sbjct: 333  QCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVV 370



 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 90/378 (23%), Positives = 159/378 (42%), Gaps = 35/378 (9%)

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
            +P+IKW ++   +    D +    S  S+LI        + + +   +   G  +C A+L
Sbjct: 3    VPVIKWKKDGIHLALGMDERKQQLSNGSLLI-------QNILHSRHHKPDEGLYQCEASL 55

Query: 4499 -----VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                 ++    +    G  P  F    ++V    G  V L  +V G     ++W KN + 
Sbjct: 56   GDSGSIISRTAKVAVAG--PLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQD 113

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P   +  +    +  L I    P D G Y C A N A  +R   E  V + +     +
Sbjct: 114  LTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPAS-SRTGNEAEVRILSDPGLHR 172

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK-PSKYFQMS 4672
             Q      P  ++       V EG      C + G P P+  W +G+++I+  SK + + 
Sbjct: 173  -QLYFLQRPSNVVAIEGKDAVLEG------C-VSGYPPPSFTWLRGEEVIQLRSKKYSLL 224

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
              ++   L IS    +D G Y CV       ++ +A+L V  P    N P+     ++  
Sbjct: 225  GGSN---LLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPS-----NLYA 276

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
            YE    +F+  ++ K  PT+ W++ G ++  +  FQ++   N  +L      + D G + 
Sbjct: 277  YESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL---GVVKSDEGFYQ 333

Query: 4793 CRATTAAGQVETSAKLVV 4810
            C A   AG  +TSA+L+V
Sbjct: 334  CVAENEAGNAQTSAQLIV 351



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 65/203 (32%), Positives = 92/203 (45%), Gaps = 14/203 (6%)

Query: 378 ETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
           E E RI +S+  L  Q   + +  +V   EGK    +  V+G P P  TW   +  I+  
Sbjct: 159 EAEVRI-LSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLR 217

Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
                L+   G   L+I+NVT  DSG+ TCV   K+   +    L V+     V P F+ 
Sbjct: 218 SKKYSLL---GGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVL-----VPPWFLN 269

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
             S L   E   +       G P P + W K+G  +IP+   +I    G S L I     
Sbjct: 270 HPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVK 326

Query: 556 SDAAWYQCTAQNVAGSTATRARL 578
           SD  +YQC A+N AG+  T A+L
Sbjct: 327 SDEGFYQCVAENEAGNAQTSAQL 349



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 36/94 (38%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP     P N    E  D +F+  +SG P P V W KNG  +I S+  +I+   N   LR
Sbjct: 264 PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSN---LR 320

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           +    KSD G Y  +AEN  G   TS  L V  P
Sbjct: 321 ILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKP 354



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 7/161 (4%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRD-DYNHKILVNESGNHALMITNVTLSDSGVVT 464
           G      C V G P P + W  N + +     + +++V  SG  AL I+ +   D G+  
Sbjct: 88  GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSG--ALQISRLQPGDIGIYR 145

Query: 465 CVARN-KSGETAFQCRLNVIEKEQVVAP-KFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
           C ARN  S  T  +  + ++    +     F++R S +   EG+  VL     G P P  
Sbjct: 146 CSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSF 205

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
           TW + G  +I     +    GG++ L I      D+  Y C
Sbjct: 206 TWLR-GEEVIQLRSKKYSLLGGSNLL-ISNVTDDDSGMYTC 244



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 6/117 (5%)

Query: 625 IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
           I    E  V  PP F+    ++ A E   I FE  +   G P   + W+KNG  +  S  
Sbjct: 253 ISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDVVIPSDY 310

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
           F  +   G  +L +L +   D G Y C A +  G A+T A L + P+  I  +S  P
Sbjct: 311 FQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL-IVPKPAIPSSSVLP 363



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 10/157 (6%)

Query: 4348 PDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTE----TTEIEHKAQTQERVVEG 4403
            P PS + + G+EV   + K+    + G   +   +T  +    T  + +K +      E 
Sbjct: 201  PPPSFTWLRGEEVIQLRSKKYSL-LGGSNLLISNVTDDDSGMYTCVVTYKNENISASAEL 259

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
             V    PP F         +E     FE    G+P+P + W +    +  S  FQI   S
Sbjct: 260  TVLV--PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGS 317

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
               IL    V   D   +  VAEN  G A+ SA L+V
Sbjct: 318  NLRIL---GVVKSDEGFYQCVAENEAGNAQTSAQLIV 351



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 12/132 (9%)

Query: 447 NHALMITNVTLS-----DSGVVTCVAR-NKSGETAFQCRLNVIEKEQVVAP-KFVERFST 499
           N +L+I N+  S     D G+  C A    SG       ++   K  V  P +F+ +  +
Sbjct: 28  NGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSI-----ISRTAKVAVAGPLRFLSQTES 82

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
           +    G+ V+L    +G P P I WQK+   + P P         +  L I R +  D  
Sbjct: 83  VTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIG 142

Query: 560 WYQCTAQNVAGS 571
            Y+C+A+N A S
Sbjct: 143 IYRCSARNPASS 154



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 7/115 (6%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            E  V  PP F+    +    ES  + FEC V  K  P   + W +NG ++     ++ V 
Sbjct: 258  ELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVP--TVNWMKNGDVVIPSDYFQIV- 314

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK--LPDIILQNQVPR 3935
              G  +L IL V   D G Y C A N+ G   T A +   K  +P   +    PR
Sbjct: 315  --GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPR 367



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 27/73 (36%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 411 FDCRVTGRPYPEVTWFIN-DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
           F+C V+G+P P V W  N D  I  DY   +     G   L I  V  SD G   CVA N
Sbjct: 284 FECTVSGKPVPTVNWMKNGDVVIPSDYFQIV-----GGSNLRILGVVKSDEGFYQCVAEN 338

Query: 470 KSGETAFQCRLNV 482
           ++G      +L V
Sbjct: 339 EAGNAQTSAQLIV 351



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 6/127 (4%)

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            ++TV+  P F     N+   E  ++  EC +   G     V W  NG  +     F+   
Sbjct: 258  ELTVLVPPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDVVIPSDYFQIVG 315

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQY 1423
              +   L +L V   D G Y C A N+ G A TS  L ++ K  +   S  PS    +  
Sbjct: 316  GSN---LRILGVVKSDEGFYQCVAENEAGNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVP 371

Query: 1424 LEDTSRY 1430
            +  +SR+
Sbjct: 372  VLVSSRF 378



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 5/93 (5%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F   PS+L   E+    FEC +         V W  NG  ++     + +      I
Sbjct: 264  PPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRI 321

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L   GV + D G Y C A N  G A  S +L V
Sbjct: 322  L---GVVKSDEGFYQCVAENEAGNAQTSAQLIV 351



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 270 QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEIITTHNHTTLRVRNT 328
           Q+P N    EG DA  +  +SG P P  TW +  + + + S K+ ++   N   L + N 
Sbjct: 178 QRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSN---LLISNV 234

Query: 329 QKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
              DSG YT +    N  I  S  L V  P
Sbjct: 235 TDDDSGMYTCVVTYKNENISASAELTVLVP 264



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 5/88 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++H +N+   E  +I FEC V     PT  + W  N   +     ++     +   L I
Sbjct: 267  FLNHPSNLYAYESMDIEFECTVSGKPVPT--VNWMKNGDVVIPSDYFQIVGGSN---LRI 321

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                + D G Y C A N  G+A TS  L
Sbjct: 322  LGVVKSDEGFYQCVAENEAGNAQTSAQL 349



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 10/98 (10%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            +V + P F+  P ++    E   + FEC +  +PV   N    W KNG  V     F+ +
Sbjct: 260  TVLVPPWFLNHPSNLY-AYESMDIEFECTVSGKPVPTVN----WMKNGDVVIPSDYFQIV 314

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
               G   L I+ ++  D G Y C A N  G  + S +L
Sbjct: 315  ---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL 349



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 7/140 (5%)

Query: 1694 TSKYQRHSAQDEV-ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVP 1752
            T K +  SA  E+ +   P F     ++   E+    FE  +   G P   V W++NG  
Sbjct: 247  TYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVS--GKPVPTVNWMKNGDV 304

Query: 1753 IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
            +  S+    +   G   L +  V   D G Y C A NE G A TS+ L V  K ++   S
Sbjct: 305  VIPSDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIV-PKPAIPSSS 360

Query: 1813 QHESALQKIQQLEDSSRYQR 1832
               SA + +  +  SSR+ R
Sbjct: 361  VLPSAPRDVVPVLVSSRFVR 380



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 8/119 (6%)

Query: 1850 LNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL 1907
            LN P+ L   E     +EC +   P P   V W  NG V+     ++     G + L IL
Sbjct: 268  LNHPSNLYAYESMDIEFECTVSGKPVPT--VNWMKNGDVVIPSDYFQI---VGGSNLRIL 322

Query: 1908 TVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKR 1966
             V   D G Y C A N  G A +S +L +  K +I   S   SA   +  +   SR+ R
Sbjct: 323  GVVKSDEGFYQCVAENEAGNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVPVLVSSRFVR 380



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F     N    +  + +FE  + G P P V+W +    ++  +     Y +  G  +
Sbjct: 264 PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSD-----YFQIVGGSN 318

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L I  +   DEG Y C A N+ G A  S  +
Sbjct: 319 LRILGVVKSDEGFYQCVAENEAGNAQTSAQL 349



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL-VECNKYSMRYNE 124
           PG      F Q   N    +G +A  EG + G P P  +W R +  + +   KYS+    
Sbjct: 168 PGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSL---- 223

Query: 125 QTGDVSLLIKQIGPGDEGEYTC 146
             G  +LLI  +   D G YTC
Sbjct: 224 -LGGSNLLISNVTDDDSGMYTC 244



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 7/103 (6%)

Query: 1167 YQIEEISKSKP--VFVQP--LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            Y+ E IS S    V V P  L++P  +   +++ +E      G P   V W  NG  V  
Sbjct: 248  YKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIP 307

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
               F+     G   L I+    +D G Y   A N  G+A TSA
Sbjct: 308  SDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSA 347



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 15/50 (30%), Positives = 26/50 (52%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            PP F++ P  +   E     F C V+G P P V W+ NG+ ++    +++
Sbjct: 264  PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQI 313



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P W +   +     E   +  E  V  K  P   + W  NG V+     F++    G   
Sbjct: 264  PPWFLNHPSNLYAYESMDIEFECTVSGKPVPT--VNWMKNGDVVIPSDYFQIV---GGSN 318

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            L ++ V + D G Y C A N+ G A TS+
Sbjct: 319  LRILGVVKSDEGFYQCVAENEAGNAQTSA 347



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 4/87 (4%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W+K+G  V  S     F   G   L I  V   D G Y C A N  G A TSA L IV
Sbjct: 296  VNWMKNGDVVIPSDY---FQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL-IV 351

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRY 1029
             K  I + S  P     +  +  +SR+
Sbjct: 352  PKPAIPSSSVLPSAPRDVVPVLVSSRF 378



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 30/117 (25%), Positives = 46/117 (39%), Gaps = 9/117 (7%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNK---PLPSGTRYKSTHDFSYVS 2832
            F+S   ++    GD +  +C V     PT  I W  N +   P+P  +R       +   
Sbjct: 76   FLSQTESVTAFMGDTVLLKCEVIGEPMPT--IHWQKNQQDLTPIPGDSRVVVLPSGA--- 130

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSAT-TSGSLRCTGDKNIYFDTQHPQGKAGLEAVE 2888
            L I+     D GIY C A N   S T     +R   D  ++      Q  + + A+E
Sbjct: 131  LQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIE 187



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            +G     + W  NG  +  S   + V   G   L ILG   +D G Y C A N+ G A+ 
Sbjct: 289  SGKPVPTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQT 345

Query: 3135 SVKL 3138
            S +L
Sbjct: 346  SAQL 349


>AF058332-2|AAD22604.1|  926|Homo sapiens myocardium-specific titin
           protein.
          Length = 926

 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 58/218 (26%), Positives = 98/218 (44%), Gaps = 8/218 (3%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P   ++  N+ +  G  A   V + G P+P++ WF NG  L  S  ++ +   +  +L +
Sbjct: 49  PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
             T+  D G YT +A N  G  + S YL + S  E +         T+T+     + +E 
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKD-------TETES-AVAKSLEK 160

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
                 P F+K  +     +G    F+  V G P P VTWF  ++Q+     + I+ N +
Sbjct: 161 LGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 220

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
           G+   ++ +    DSG+  C A N  GE+     L V+
Sbjct: 221 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVL 258



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 61/214 (28%), Positives = 96/214 (44%), Gaps = 12/214 (5%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P F     N +++ G +  L   V G     + W  NG  + P    K + +   ++L+I
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA----------PP 4623
            L    +D G+Y C+A N  G+  C A   ++      K   +T++A A          PP
Sbjct: 109  LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK-DTETESAVAKSLEKLGGPCPP 167

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRI 4682
              ++ LK    A+G    F   +VG+P PTV W+K +K +  S Y+ +    +   T  +
Sbjct: 168  HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 227

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            ++   ED G Y C A N  G  T AA+L V   D
Sbjct: 228  NDPQREDSGLYICKAENMLGESTCAAELLVLLED 261



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 68/235 (28%), Positives = 107/235 (45%), Gaps = 17/235 (7%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F K + NA+++ G    L  T+  +  P  +++W+ NG  +     +K  +D    +L
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSL 106

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             IL+   ED G Y C A+N  G+ + ++ +K+++K   + DT  E  + K   LEK   P
Sbjct: 107  IILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--SLEKLGGP 164

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
             P         P FL  L  +    +G  A FE  V  + +P  T+ WF   +++     
Sbjct: 165  CP---------PHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVY 212

Query: 2158 YRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
            Y   H+  G     +     EDSG Y+CKA N LGE+     L V      + DT
Sbjct: 213  YTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 267



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/218 (24%), Positives = 91/218 (41%), Gaps = 22/218 (10%)

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
           + +  ++   P F+K   + D++ G +      V G P P++ WF N   +    ++K  
Sbjct: 39  KFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK-F 97

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV---------IEKEQVVA-- 490
           V +  +H+L+I    L D G  TC+A N  G+T     L +          E E  VA  
Sbjct: 98  VFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKS 157

Query: 491 ---------PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR-IH 540
                    P F++    +   +G P +     VG P P +TW K+   +  +     IH
Sbjct: 158 LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIH 217

Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              G+ T  +   +  D+  Y C A+N+ G +   A L
Sbjct: 218 NPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 255



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 53/209 (25%), Positives = 97/209 (46%), Gaps = 21/209 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P  I+ + +  ++ G     S  ++G P P +QW+    L+ PS  ++     D+++L I
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-----------TQPDQADNLPAL------- 4724
                 EDEG+Y C+A N  G+   +A LK+           T+   A +L  L       
Sbjct: 109  LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168

Query: 4725 --TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIG 4781
                L+ I   +G PA F+  +  +  PT+ W +E   +  +  + +IH  N +   ++ 
Sbjct: 169  FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED+G + C+A    G+   +A+L+V
Sbjct: 229  DPQREDSGLYICKAENMLGESTCAAELLV 257



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 72/276 (26%), Positives = 119/276 (43%), Gaps = 22/276 (7%)

Query: 1796 TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTK 1855
            +SS L  + +     E Q     + ++ L +S  Y  + D E      P FI +++    
Sbjct: 2    SSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKE-GTGPIFIKEVSN-AD 59

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            +S G  A     +   P P  +++W+FNG +L     Y+   D    +L IL    ED G
Sbjct: 60   ISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEG 117

Query: 1916 EYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK-IQYLEDDSRYKRAVQDDSFV 1974
            EYTC A N+ G+ + S  L + SK    +D++ ESA+ K ++ L                
Sbjct: 118  EYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC------------ 165

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD-FG 2033
               P F K +K     +G P   E T+  V +P   V W+   + +     +   ++  G
Sbjct: 166  --PPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNG 221

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                 +     ED+G Y+CKA N +GE+   + + V
Sbjct: 222  SGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 257



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 73/256 (28%), Positives = 109/256 (42%), Gaps = 24/256 (9%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            E L+ L +S V       E+E G  P+F   +SN + +  G+ A     +T    P  K+
Sbjct: 25   ETLELLSESPVYPTKFDSEKE-GTGPIFIKEVSNAD-ISMGDVATLS--VTVIGIPKPKI 80

Query: 3455 EWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            +W++NG  L   + ++   D     L I  T  ED GEY C A N+YG+ + +A +K+  
Sbjct: 81   QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 140

Query: 3515 KRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSS 3574
            K     E       E  + K  +LE   G             PP F      +  ++   
Sbjct: 141  KG----EGHKDTETESAVAK--SLEKLGGPC-----------PPHFLKELKPIRCAQGLP 183

Query: 3575 AHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI-NDFGFVILEIGGVYQRDAGLYTCK 3633
            A FE  +  V + +  V WF   K L T      I N  G     +    + D+GLY CK
Sbjct: 184  AIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICK 241

Query: 3634 ATNRHGEATVSCKLQV 3649
            A N  GE+T + +L V
Sbjct: 242  AENMLGESTCAAELLV 257



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 68/231 (29%), Positives = 101/231 (43%), Gaps = 19/231 (8%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            + +G  P F   + N + +  G  A    TV+ +  P  KI+W+ NG  +  S   K V 
Sbjct: 43   EKEGTGPIFIKEVSNAD-ISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVF 99

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
            D     L I +T+  D GEY C A N YG+    A +    KG  + ++    ++AK   
Sbjct: 100  DGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--S 157

Query: 3263 LESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNG 3322
            LE L G     P      PP F+ +++ + +  +G  A FE  +  V +P   V WF   
Sbjct: 158  LEKLGG-----PC-----PPHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKEN 204

Query: 3323 KKLPHGHRYRTFHD-FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            K+L     Y   H+  G     +     E+SG Y C A N LG  +  A L
Sbjct: 205  KQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 255



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 73/237 (30%), Positives = 101/237 (42%), Gaps = 16/237 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI+WF NGV LT  A  K  FD    +L I   + +D G YTC A+N  G+ + +A 
Sbjct: 76   PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAY 135

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            +KI  +    GE  H D+ +   A+                   F+  L  I C +G   
Sbjct: 136  LKINSK----GEG-HKDT-ETESAVAKSLEKLGGPCPPH-----FLKELKPIRCAQGLPA 184

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH-TYEEDSGIYTCKA 2850
             FE  V     PT  + WF  NK L +   Y   H+ +     I +    EDSG+Y CKA
Sbjct: 185  IFEYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKA 242

Query: 2851 TNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTE 2907
             N  G +T +  L    +     DT   + K+  EA E   +  L KG      D+E
Sbjct: 243  ENMLGESTCAAELLVLLEDTDMTDTP-CKAKSTPEAPEDFPQTPL-KGPAVEALDSE 297



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 71/267 (26%), Positives = 105/267 (39%), Gaps = 27/267 (10%)

Query: 4395 QTQERVVEGPVKPSK--------PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            +T E + E PV P+K         PIF K++    +   + A   V   G P P I+W+ 
Sbjct: 25   ETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFF 84

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
                +  S D++         LII    +ED   +  +A N  G   CSA L +  K   
Sbjct: 85   NGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEG 144

Query: 4507 GR---------------GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
             +               GG  PP F    + +    G     +  V G     V W K  
Sbjct: 145  HKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKEN 204

Query: 4552 KKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT-- 4608
            K++   +   I+   +G+ T ++ +   +DSG Y C A N  GE+ C AE +V L  T  
Sbjct: 205  KQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDM 264

Query: 4609 KDKPKPQTKAANAPPEIIE-PLKDKIV 4634
             D P        AP +  + PLK   V
Sbjct: 265  TDTPCKAKSTPEAPEDFPQTPLKGPAV 291



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 63/237 (26%), Positives = 106/237 (44%), Gaps = 19/237 (8%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P+F   + +  ++    A     +I  G PK +++W  NGV +  S     + D    +L
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTVI--GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSL 106

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             + +   ED G YTC A N+ G+ + S+ L + SK     +++ ESA+ K   LE     
Sbjct: 107  IILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--SLE----- 159

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
                  ++     P F+ +L  P + ++G  A +E  +   P P   V W+   K L + 
Sbjct: 160  ------KLGGPCPPHFLKELK-PIRCAQGLPAIFEYTVVGEPAPT--VTWFKENKQLCTS 210

Query: 1891 HRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946
              Y    N  G     +     EDSG Y CKA N LG++  +  L V  +++ + D+
Sbjct: 211  VYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 267



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 74/284 (26%), Positives = 122/284 (42%), Gaps = 21/284 (7%)

Query: 2064 TSSVKVDAKSGLYLDTLDEQRLKKIQEL--EKYERPKPIEEEQPGQRPVFLTALTSLENL 2121
            +SS     + GL+   L   ++ +  EL  E    P   + E+ G  P+F+  +++ + +
Sbjct: 2    SSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-I 60

Query: 2122 KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
              GD A     V  I  P   I WF NG  +     Y+   D    +L IL+T  ED G 
Sbjct: 61   SMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGE 118

Query: 2182 YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISP 2241
            Y C A+N  G+ + +  LK+        DT+  + + K   LE  G             P
Sbjct: 119  YTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--SLEKLGGP----------CP 166

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGYV 2300
            P F+ EL+      +G  A FE  V  V +P   + ++   K L ++  + I  +  G  
Sbjct: 167  PHFLKELK-PIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 223

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344
            +  +     ED+G Y  KA N LG  T A  + V  + + ++++
Sbjct: 224  TFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 267



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 66/275 (24%), Positives = 115/275 (41%), Gaps = 19/275 (6%)

Query: 1130 SASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPV 1189
            S+S        + ++ +      +T  +     V P     E   + P+F++ +SN   +
Sbjct: 2    SSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-I 60

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGE 1249
            S G    L   +  +G P  +++WF NG  +T  + +K  +D    +L I+     D GE
Sbjct: 61   SMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGE 118

Query: 1250 YTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            YT  A N  G    SA +++  + +   DT+ E A+             K + E +    
Sbjct: 119  YTCMASNDYGKTICSAYLKINSKGEGHKDTETESAV------------AKSL-EKLGGPC 165

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
             P F + L  I   +G     E  +  VG+    V WF   K + T   +   +  +   
Sbjct: 166  PPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 223

Query: 1370 LDLLS-VYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
              +++    EDSG+Y C+A N LGE+  +  L V+
Sbjct: 224  TFIVNDPQREDSGLYICKAENMLGESTCAAELLVL 258



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 65/235 (27%), Positives = 105/235 (44%), Gaps = 25/235 (10%)

Query: 2234 VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHD--------PNLRIEFYHNGKAL 2285
            + E  + P +F +E  GT  +F  + ++ +  +  V          P  +I+++ NG  L
Sbjct: 30   LSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLL 89

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQ 2345
              +A +   FD    SL I     ED GEY+  A N  G    +  + + +KG       
Sbjct: 90   TPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG------- 142

Query: 2346 RPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGD 2405
              EG  K  E ESA      ++  P     P F + L+ I    +G  A F+  +  VG+
Sbjct: 143  --EG-HKDTETESAVAKSLEKLGGPCP---PHFLKELKPI-RCAQGLPAIFEYTV--VGE 193

Query: 2406 PTLKVEWFRNEKLIEDSSRITKTHD-FGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            P   V WF+  K +  S   T  H+  G  +  ++  + ED G+Y+C+A N+LGE
Sbjct: 194  PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGE 248



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 65/251 (25%), Positives = 105/251 (41%), Gaps = 19/251 (7%)

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
            E +++L + S  + T    E     PI    + N +I  G  A     +I +     K++
Sbjct: 25   ETLELLSE-SPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP--KIQ 81

Query: 1613 WYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            W+ N   L   + +    +    +L I+    ED G YTC A N  G+ + S    ++SK
Sbjct: 82   WFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSK 141

Query: 1673 KSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEA 1732
               + +++ E A+ +   LE                  P F   +K IR A+   A FE 
Sbjct: 142  GEGHKDTETESAVAK--SLEKLGG-----------PCPPHFLKELKPIRCAQGLPAIFEY 188

Query: 1733 RLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-FGYVALNMKYVNPEDSGTYTCRAINEL 1791
             +  VG+P   V W +    +  S   T +H+  G     +     EDSG Y C+A N L
Sbjct: 189  TV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENML 246

Query: 1792 GEAVTSSTLFV 1802
            GE+  ++ L V
Sbjct: 247  GESTCAAELLV 257



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 59/211 (27%), Positives = 92/211 (43%), Gaps = 19/211 (9%)

Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET 722
           +G P  KI+W  NG  +  S+ +  +F     SL +L   ++D GEYTC A +  G    
Sbjct: 73  IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTIC 132

Query: 723 KAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ-RPQFIRPLQDLGE 781
            A L +  +        H +T       E  S     +S+E+      P F++ L+ +  
Sbjct: 133 SAYLKINSKG-----EGHKDT-------ETESAVA--KSLEKLGGPCPPHFLKELKPI-R 177

Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGYVSLNIMHLRAEDA 840
             +G  A FE   T V +P   V W+K+ + +  S   T I N  G  +  +   + ED+
Sbjct: 178 CAQGLPAIFE--YTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDS 235

Query: 841 GSYTVRAVNKLGEAISTASIRVAARSTVTAD 871
           G Y  +A N LGE+   A + V    T   D
Sbjct: 236 GLYICKAENMLGESTCAAELLVLLEDTDMTD 266



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 66/269 (24%), Positives = 108/269 (40%), Gaps = 29/269 (10%)

Query: 3788 SAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGV 3847
            SA+ + +  ++L      E ++ L    +     +     T P FI ++ +  +   +  
Sbjct: 7    SAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVA 66

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
                 V     PK +I+W+ NG LL     Y+ V+D    SL IL+   ED GEY C A 
Sbjct: 67   TLSVTVIGI--PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMAS 124

Query: 3908 NDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDV 3967
            ND+G+    A +           N    G K +E  + +  +++K               
Sbjct: 125  NDYGKTICSAYLKI---------NSKGEGHKDTETESAVAKSLEKLGGPC---------- 165

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
                PP F+ +++       +    FE  +  VG+P   V WF   K L     +T I++
Sbjct: 166  ----PPHFLKELKPIRCAQGLPAI-FEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHN 218

Query: 4028 -FGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
              G           EDSG Y+C+A N+ G
Sbjct: 219  PNGSGTFIVNDPQREDSGLYICKAENMLG 247



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 68/244 (27%), Positives = 100/244 (40%), Gaps = 34/244 (13%)

Query: 3022 LEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI--VDISEGQIAHYEASLIPTGDQS 3079
            L KI    + L + P      D+ +        K++   DIS G +A    ++I  G   
Sbjct: 20   LSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVI--GIPK 77

Query: 3080 MVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
              I+WF+NG  +  S   + V+      L IL TK  D G Y+C A+N +G+   S  L+
Sbjct: 78   PKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLK 137

Query: 3140 CVDKSKGQK--------------------PRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
               K +G K                    P F   ++ I     G  A FE TV  V +P
Sbjct: 138  INSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIR-CAQGLPAIFEYTV--VGEP 194

Query: 3180 DMKIEWYHNGQPMRHS---TRIKTVSDFG-FVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               + W+   + +  S   T I   +  G F+V D    Q  DSG Y+C+A N  GE   
Sbjct: 195  APTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVND---PQREDSGLYICKAENMLGESTC 251

Query: 3236 RATI 3239
             A +
Sbjct: 252  AAEL 255



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 65/254 (25%), Positives = 98/254 (38%), Gaps = 24/254 (9%)

Query: 3672 IQKLEETLHKREEITI-----EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT 3726
            + K+ ETL    E  +     + EK       ++   N D+  G        V  +G P 
Sbjct: 20   LSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTV--IGIPK 77

Query: 3727 MRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             +I WF NG      +    + D    +L I +    D GEYTC A+N +G      K  
Sbjct: 78   PKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYG------KTI 131

Query: 3787 CSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846
            CSA   I           GE  K+ E         E+     PP F+ ++K     +   
Sbjct: 132  CSAYLKI--------NSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLP 183

Query: 3847 VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICR 3905
              FE  V  +  P   + W++  K L +   Y  +++  G  +  +     EDSG YIC+
Sbjct: 184  AIFEYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICK 241

Query: 3906 AVNDFGEDFTKATI 3919
            A N  GE    A +
Sbjct: 242  AENMLGESTCAAEL 255



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 64/238 (26%), Positives = 93/238 (39%), Gaps = 20/238 (8%)

Query: 2355 ELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
            EL S  P    +         P+F + + N D I  G  A     +I  G P  K++WF 
Sbjct: 28   ELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTVI--GIPKPKIQWFF 84

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXI 2474
            N  L+  S+      D    S+ I   + EDEG Y C ASN  G+               
Sbjct: 85   NGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEG 144

Query: 2475 QLETQHPEGM-KKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVV 2533
              +T+    + K ++KL  P              P F + L  P    +G  A +E  V 
Sbjct: 145  HKDTETESAVAKSLEKLGGPC------------PPHFLKELK-PIRCAQGLPAIFEYTV- 190

Query: 2534 PVGDPSLRFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
             VG+P+    W+    +L     +   H+  G  T  +N     D+GLY+CKA N  G
Sbjct: 191  -VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG 247



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 67/261 (25%), Positives = 101/261 (38%), Gaps = 28/261 (10%)

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEP----PKFITQIQDVTKLVEGQSAHFEARLVPVDDP 3312
            L+KI E   L       P+   +E     P FI ++ +   +  G  A     ++ +  P
Sbjct: 20   LSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTVIGIPKP 78

Query: 3313 DLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              K++WF+NG  L     Y+   D     L IL+   E+ GEY C+A+N  G+    A L
Sbjct: 79   --KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYL 136

Query: 3373 KCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENL 3432
            K  SK     D++    +   LEKL                   G  P   +        
Sbjct: 137  KINSKGEGHKDTETESAVAKSLEKL------------------GGPCPPHFLKELKPIRC 178

Query: 3433 REGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD-FGFVILEISPTYPEDSG 3491
             +G  A FE   T   +P   V W+   K L     +    +  G     ++    EDSG
Sbjct: 179  AQGLPAIFE--YTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 236

Query: 3492 EYLCRAYNNYGEAVTTASMKV 3512
             Y+C+A N  GE+   A + V
Sbjct: 237  LYICKAENMLGESTCAAELLV 257



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 68/258 (26%), Positives = 103/258 (39%), Gaps = 29/258 (11%)

Query: 3532 IDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV 3591
            I++   L   S    T     + G  P F    S+  +S    A     +I +     ++
Sbjct: 23   INETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGI--PKPKI 80

Query: 3592 EWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            +WF NG  L   +  K + D     L I      D G YTC A+N +G+   S  L++  
Sbjct: 81   QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 140

Query: 3652 RQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGG 3711
            +           H  + TES   + ++L K          P PP F  E+K  I   +G 
Sbjct: 141  KG--------EGHKDTETES--AVAKSLEKL-------GGPCPPHFLKELKP-IRCAQGL 182

Query: 3712 PVHFDCRVEPVGDPTMRIDWFHNGRPFATG---SRVHTLNDFG-FIALDIDYIYARDAGE 3767
            P  F+  V  VG+P   + WF   +   T    + +H  N  G FI  D       D+G 
Sbjct: 183  PAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQ---REDSGL 237

Query: 3768 YTCRATNKWGSATTTAKI 3785
            Y C+A N  G +T  A++
Sbjct: 238  YICKAENMLGESTCAAEL 255



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 58/229 (25%), Positives = 94/229 (41%), Gaps = 27/229 (11%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + + N +   G    L   +  +G    +++WF NG  +     ++  ++ D  +L
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSL 106

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK----KDLILESQHPSGLEKIQYLED 1426
             +L    ED G YTC A+N  G+ + S  L++ +K    KD   ES     LEK+     
Sbjct: 107  IILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKL----- 161

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
                             P F+   K I    +G    FE  +  V +    V WFK  + 
Sbjct: 162  ------------GGPCPPHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQ 206

Query: 1487 VTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            +     +  IH+  G     + D   EDSG+Y C+A N++G    +  L
Sbjct: 207  LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 255



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 44/148 (29%), Positives = 67/148 (45%), Gaps = 13/148 (8%)

Query: 211 NGTDHSSTDDFKV--DTFEYRLLREVSFRESITKRYV-------GESDVQISTEIDRSL- 260
           +G DHS    F    D  EY  +    + ++I   Y+       G  D +  + + +SL 
Sbjct: 100 DGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLE 159

Query: 261 --GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
             G   PP   ++ +  +  +G  A F+  + G P P VTWFK  ++L  S  + II   
Sbjct: 160 KLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNP 219

Query: 319 NHT-TLRVRNTQKSDSGHYTLLAENPNG 345
           N + T  V + Q+ DSG Y   AEN  G
Sbjct: 220 NGSGTFIVNDPQREDSGLYICKAENMLG 247



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 5/125 (4%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            +I  K    + TE E         + GP     PP F K+++P R  +   A FE    G
Sbjct: 137  KINSKGEGHKDTETESAVAKSLEKLGGPC----PPHFLKELKPIRCAQGLPAIFEYTVVG 192

Query: 4437 EPLPLIKWYRENFPIKNSPDFQ-IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            EP P + W++EN  +  S  +  IH  +     I+     EDS ++   AEN  G + C+
Sbjct: 193  EPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCA 252

Query: 4496 ANLVV 4500
            A L+V
Sbjct: 253  AELLV 257



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 75/299 (25%), Positives = 109/299 (36%), Gaps = 28/299 (9%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            +FI  ++N     GD       V     P  KI+WFFN   L     YK   D    SL 
Sbjct: 50   IFIKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSLI 107

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I  T  ED G YTC A+N  G    S  L+       + DT+               E+ 
Sbjct: 108  ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTE--------------TESA 153

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
            +AK    S+     P P   +      +  +G     E  V    +P   + W+   K L
Sbjct: 154  VAK----SLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQL 207

Query: 2955 EQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERT 3013
                 + +  +  G  T  + D    DSG+Y CKA N  GE+  ++ +    +D   + T
Sbjct: 208  CTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDT--DMT 265

Query: 3014 QHP-KGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFT--TVFKDIVDISEGQIAHYE 3069
              P K     E  ++   +  K P  +  D       F   T+ K  +   E Q   YE
Sbjct: 266  DTPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYE 324



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 36/114 (31%), Positives = 49/114 (42%), Gaps = 2/114 (1%)

Query: 49  TTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK 108
           T ++ S     P       E + PIF +   NA  + G  A     + G P P + W   
Sbjct: 26  TLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFN 85

Query: 109 KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
              L     Y   ++    D SL+I      DEGEYTC A N YG+ ICS Y++
Sbjct: 86  GVLLTPSADYKFVFDGD--DHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLK 137



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 1/92 (1%)

Query: 67  GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
           G P PP F +  K  R AQG  A FE  + G P P V+W ++   L     Y++ +N   
Sbjct: 162 GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHN-PN 220

Query: 127 GDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
           G  + ++      D G Y C A N  GE+ C+
Sbjct: 221 GSGTFIVNDPQREDSGLYICKAENMLGESTCA 252



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 56/207 (27%), Positives = 87/207 (42%), Gaps = 24/207 (11%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI+W+FNG +L   + +K   D    +L ++     D G YTC A N  G+   S+ 
Sbjct: 76   PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAY 135

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            +   SK          +G +  E    +  SL K  G         PP F    K I   
Sbjct: 136  LKINSKG---------EGHKDTETESAVAKSLEKLGGP-------CPPHFLKELKPI-RC 178

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSG 3119
            ++G  A +E +++  G+ +  + WF   K +  S     ++   G     +   +  DSG
Sbjct: 179  AQGLPAIFEYTVV--GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 236

Query: 3120 TYSCRATNKWGQ----AEISVKLECVD 3142
             Y C+A N  G+    AE+ V LE  D
Sbjct: 237  LYICKAENMLGESTCAAELLVLLEDTD 263



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 58/242 (23%), Positives = 103/242 (42%), Gaps = 31/242 (12%)

Query: 3943 LTQMEATIKKYT-SEVYLTEDDLYDVDKKQP-PRFVTQIQS-QTSLVEMETTKFECQLAP 3999
            L+++  T++  + S VY T+   +D +K+   P F+ ++ +   S+ ++ T      +  
Sbjct: 20   LSKINETLELLSESPVYPTK---FDSEKEGTGPIFIKEVSNADISMGDVATLS----VTV 72

Query: 4000 VGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDET 4059
            +G P  K++WFFNG  L     +  ++D    ++   +   ED GEY C A+N YG    
Sbjct: 73   IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTIC 132

Query: 4060 KAVIKTTGKPGIVYDSQLPKHM-KSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPD 4118
             A +K   K     D++    + KS+EK+                     CPP F+    
Sbjct: 133  SAYLKINSKGEGHKDTETESAVAKSLEKL------------------GGPCPPHFLKELK 174

Query: 4119 AVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYD 4176
             +   +G  A F   V G P P V W      +     Y + +  +G   F +   ++ D
Sbjct: 175  PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQRED 234

Query: 4177 TG 4178
            +G
Sbjct: 235  SG 236



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 57/245 (23%), Positives = 93/245 (37%), Gaps = 20/245 (8%)

Query: 2491 EQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVE 2550
            E P      + ++E   PIF + ++  +++  G  A     V+  G P  + +W+ NGV 
Sbjct: 32   ESPVYPTKFDSEKEGTGPIFIKEVSN-ADISMGDVATLSVTVI--GIPKPKIQWFFNGVL 88

Query: 2551 LKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQA 2610
            L   + ++   D    +L I      D G Y C A N  G                    
Sbjct: 89   LTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS-------- 140

Query: 2611 MRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRT 2670
             + E  +  + + A    + ++    G    P F   LK   +  +G     E  V    
Sbjct: 141  -KGEGHKDTETESAVAKSLEKL----GGPCPPHFLKELKPI-RCAQGLPAIFEYTVVGEP 194

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFD-FGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729
             P   + WFK    L T        +  G  T  +N  + +DSG+Y CKA N+LGE+   
Sbjct: 195  APT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCA 252

Query: 2730 ASIKI 2734
            A + +
Sbjct: 253  AELLV 257



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I  PL D +  EG  +  +  I       V WY  +KL+   + F+  +  + YTL I
Sbjct: 835  PMIHTPLVDTVSEEGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVI 892

Query: 4683 SEAFPED-EGDYKCVAYNSAGRVTVAAKLKVTQ 4714
             +   ED +G+Y C A N +G+   +AKL V +
Sbjct: 893  DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 925



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 53/194 (27%), Positives = 80/194 (41%), Gaps = 16/194 (8%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            K++WF NG  +T    ++ + D    +L I+    ED G YTC A N  G    S  L  
Sbjct: 79   KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 138

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
             S  +  + T+ E+ +   + LE                  P     LK +   +G  A 
Sbjct: 139  NSKGEGHKDTETESAV--AKSLEKLG-----------GPCPPHFLKELKPIRCAQGLPAI 185

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN-FGFVALDIMSCLPEDSGTYTCRAI 1655
            FE  +  V +    V W+  NK L +   +T  +N  G     +     EDSG Y C+A 
Sbjct: 186  FEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAE 243

Query: 1656 NALGEAVTSGIAIV 1669
            N LGE+  +   +V
Sbjct: 244  NMLGESTCAAELLV 257



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 49/210 (23%), Positives = 88/210 (41%), Gaps = 22/210 (10%)

Query: 794  LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            +T +  P  +++W+ +G  +T S+    +F+    SL I+  + ED G YT  A N  G+
Sbjct: 70   VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGK 129

Query: 854  AISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKT 913
             I +A +++ ++     D    E    + K+                        P F  
Sbjct: 130  TICSAYLKINSKGEGHKD---TETESAVAKSLEKLG---------------GPCPPHFLK 171

Query: 914  PIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN-FGYVALTIK 972
             +K  I   +G  A FE  +  +G+    V W K+ + +  S   T   N  G     + 
Sbjct: 172  ELK-PIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
                 D+G Y C+A N +G++T +A L ++
Sbjct: 229  DPQREDSGLYICKAENMLGESTCAAELLVL 258



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/79 (32%), Positives = 40/79 (50%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G  A     +    KP IQW   G L+  + D++ + +G++  L+I  T  ED G +TC 
Sbjct: 63   GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 122

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            A+   G+   SA L + SK
Sbjct: 123  ASNDYGKTICSAYLKINSK 141



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 8/123 (6%)

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIV----PPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            E    +++     V   K ++  GG++    P   T     V+   G +V L T +T  K
Sbjct: 804  EKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAK 862

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD-SGKYECVAINSAGEARCDAE 4600
              +V W    K V  D + K L++  TYTL+I +   +D  G+Y C A+N +G+    A+
Sbjct: 863  --EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAK 920

Query: 4601 CVV 4603
              V
Sbjct: 921  LTV 923



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
            TPL D V  EG      T IT+  +  + W  E  L+P    F+ + + N   L+I    
Sbjct: 839  TPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVN 896

Query: 4785 EED-TGTFTCRATTAAGQVETSAKLVV 4810
             ED  G + C A   +G+  TSAKL V
Sbjct: 897  TEDHQGEYVCEALNDSGKTATSAKLTV 923



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L + V +EGD +H   ++  +++    + W+F NK +PS  ++K   D +  +L I    
Sbjct: 841  LVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVN 896

Query: 2840 EED-SGIYTCKATNSKGSATTSGSL 2863
             ED  G Y C+A N  G   TS  L
Sbjct: 897  TEDHQGEYVCEALNDSGKTATSAKL 921



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 14/118 (11%)

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866
            KI+E E G I +   + P++ TP      +     EE + V     +   ++    + WY
Sbjct: 821  KIQEAEGGLIKE---DGPMIHTP------LVDTVSEEGDIVHLTTSITNAKE----VNWY 867

Query: 3867 RNGKLLPSGHRYRTVYDMGFVSLDILYVYAED-SGEYICRAVNDFGEDFTKATISCKK 3923
               KL+PS  +++ + D    +L I  V  ED  GEY+C A+ND G+  T A ++  K
Sbjct: 868  FENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVK 925



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 13/135 (9%)

Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGP--------TKLSEGQSA 1862
            E Q ES     ++ E SS     E   V + +A   + + +GP        T   EG   
Sbjct: 793  EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIV 852

Query: 1863 HYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED-SGEYTCKA 1921
            H    I    + N    WYF  K++ S  +++   D     L I  V  ED  GEY C+A
Sbjct: 853  HLTTSITNAKEVN----WYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEA 908

Query: 1922 INNLGQAVSSIRLNV 1936
            +N+ G+  +S +L V
Sbjct: 909  LNDSGKTATSAKLTV 923



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 52/201 (25%), Positives = 84/201 (41%), Gaps = 17/201 (8%)

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            IG    +++W  +G  +  S+     F+    +L I    + D G YTC A N  G+   
Sbjct: 73   IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTIC 132

Query: 996  SANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKI 1055
            SA L I +K +   +++    + K             + E++     P FL  LK   + 
Sbjct: 133  SAYLKINSKGEGHKDTETESAVAK-------------SLEKLGGPCPPHFLKELKPI-RC 178

Query: 1056 VEGQSAHFEARVEPQSDLTMTVEWYFNGKQI-TSANRIQTYHDFGYVALDIASVRAEDSG 1114
             +G  A FE  V    +   TV W+   KQ+ TS      ++  G     +   + EDSG
Sbjct: 179  AQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 236

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
            +Y   A N  GE+  +A + V
Sbjct: 237  LYICKAENMLGESTCAAELLV 257



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 11/123 (8%)

Query: 3391 EGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDP 3450
            E G E++ T++   ++  +  + +E G  P+   PL +  +  EG+  H    +T   + 
Sbjct: 811  ESGTEEVATVK---IQEAEGGLIKEDG--PMIHTPLVDTVS-EEGDIVHLTTSITNAKEV 864

Query: 3451 NLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPED-SGEYLCRAYNNYGEAVTTAS 3509
            N    WY+  K + +  +F+   D     L I     ED  GEY+C A N+ G+  T+A 
Sbjct: 865  N----WYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAK 920

Query: 3510 MKV 3512
            + V
Sbjct: 921  LTV 923



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/128 (22%), Positives = 51/128 (39%), Gaps = 2/128 (1%)

Query: 4081 MKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKP 4140
            +  I +  E+ +   V P +   E K    P+F+       +  G+ A     V G PKP
Sbjct: 20   LSKINETLELLSESPVYPTKFDSE-KEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP 78

Query: 4141 RVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199
            ++ W  NG  +   + YK  +DG  H   I  T+  D G+   +             LK+
Sbjct: 79   KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 138

Query: 4200 IPRHDDYR 4207
              + + ++
Sbjct: 139  NSKGEGHK 146



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 6/145 (4%)

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIK 1985
            + V+S  ++ + ++  ++ S+ +         E+ +  K    +   + E  P    P+ 
Sbjct: 783  KGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLV 842

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            +    EG  VHL  ++T   +    V WY   + V    +FK   D     L I     E
Sbjct: 843  DTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE 898

Query: 2046 D-TGTYMCKATNAVGEAVTTSSVKV 2069
            D  G Y+C+A N  G+  T++ + V
Sbjct: 899  DHQGEYVCEALNDSGKTATSAKLTV 923



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 6/97 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P   TP+ D +S +EG   H    +     +   V W  + + V +  +     +     
Sbjct: 835  PMIHTPLVDTVS-EEGDIVHLTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYT 889

Query: 969  LTIKSVTVHD-AGHYTCRAYNAIGQATTSANLTIVTK 1004
            L I  V   D  G Y C A N  G+  TSA LT+V +
Sbjct: 890  LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 926



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 43/204 (21%), Positives = 82/204 (40%), Gaps = 17/204 (8%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            ++W+FNG  +T +   +   D    +L I   + ED G YT +A N  G+   SA + + 
Sbjct: 80   IQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKIN 139

Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196
            ++          G  +       +K +E +          P F++ L    P+   + + 
Sbjct: 140  SKG--------EGHKDTETESAVAKSLEKLG-----GPCPPHFLKELK---PIRCAQGLP 183

Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIH-ATSADTGEYTVRAV 1255
                   +G+P   V WF   + +     +   ++       I++     D+G Y  +A 
Sbjct: 184  AIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAE 243

Query: 1256 NHLGSAHTSAIVRVIERSDIVTDT 1279
            N LG +  +A + V+     +TDT
Sbjct: 244  NMLGESTCAAELLVLLEDTDMTDT 267



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERD-SGI 2983
            EG ++HL   +    +    + WYF  K++    +FK   D    TL +  V   D  G 
Sbjct: 848  EGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 903

Query: 2984 YTCKAYNKRGEAFTSS 2999
            Y C+A N  G+  TS+
Sbjct: 904  YVCEALNDSGKTATSA 919



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 4/82 (4%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVV 463
           EG +      +T     EV W+  ++ +  D   K L +++  + L+I  V   D  G  
Sbjct: 848 EGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEY 904

Query: 464 TCVARNKSGETAFQCRLNVIEK 485
            C A N SG+TA   +L V+++
Sbjct: 905 VCEALNDSGKTATSAKLTVVKR 926



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/137 (21%), Positives = 59/137 (43%), Gaps = 10/137 (7%)

Query: 1270 IERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVH 1329
            ++ S+   ++ +E   E++  ++        ++ED  ++  P     L +  + EG  VH
Sbjct: 799  LKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTP-----LVDTVSEEGDIVH 853

Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED-SGVYTCQAT 1388
            L   +         V W+   K + +  +F+   + +   L +  V  ED  G Y C+A 
Sbjct: 854  LTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 909

Query: 1389 NQLGEAVTSCALRVIAK 1405
            N  G+  TS  L V+ +
Sbjct: 910  NDSGKTATSAKLTVVKR 926



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-FGYI 694
           PP F+  LK +   +G    FE  +  VG+P   + W K  + +  S  +T I    G  
Sbjct: 166 PPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 223

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           +  +     +DSG Y C+A +  G +   A L V
Sbjct: 224 TFIVNDPQREDSGLYICKAENMLGESTCAAELLV 257



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 11/130 (8%)

Query: 3658 EPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDC 3717
            E +  S  +SGTE +  ++  + + E   I+++ P        + D +   EG  VH   
Sbjct: 803  EEKEESSSESGTEEVATVK--IQEAEGGLIKEDGP---MIHTPLVDTVS-EEGDIVHLTT 856

Query: 3718 RVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD-AGEYTCRATNKW 3776
             +    +    ++W+   +   +  +   L D     L ID +   D  GEY C A N  
Sbjct: 857  SITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDS 912

Query: 3777 GSATTTAKIT 3786
            G   T+AK+T
Sbjct: 913  GKTATSAKLT 922



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 37/136 (27%), Positives = 51/136 (37%), Gaps = 18/136 (13%)

Query: 3011 ERTQHPKGTEGLE--KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHY 3068
            E +    GTE +   KIQ  E  L KE G          P   T   D V   EG I H 
Sbjct: 806  EESSSESGTEEVATVKIQEAEGGLIKEDG----------PMIHTPLVDTVS-EEGDIVHL 854

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD-SGTYSCRATN 3127
              S+    +    + W++  K + +  + + +       L I    T D  G Y C A N
Sbjct: 855  TTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALN 910

Query: 3128 KWGQAEISVKLECVDK 3143
              G+   S KL  V +
Sbjct: 911  DSGKTATSAKLTVVKR 926



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAED-SGVYTVVARNAAGEAQLSASMTV 1135
            V WYF  K + S  + +   D     L I  V  ED  G Y   A N +G+   SA +TV
Sbjct: 864  VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 923

Query: 1136 ETR 1138
              R
Sbjct: 924  VKR 926



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDI-LYCYEENSGEYECVATNKLGRDSTKANL 3372
            +V W++  K +P   +++   D     L I     E++ GEY C A N  G+ +T A L
Sbjct: 863  EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 921



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 5/96 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P    PL    + EG  +H  T I    +    + W    + + +  +F  +      +L
Sbjct: 835 PMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTL 890

Query: 697 DMLSLNIQD-SGEYTCRAVSATGVAETKAVLHVTPR 731
            +  +N +D  GEY C A++ +G   T A L V  R
Sbjct: 891 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 926



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/113 (23%), Positives = 45/113 (39%), Gaps = 6/113 (5%)

Query: 1692 EDTSKYQRHSAQDEVITQ-APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            E+ +  +   A+  +I +  P+   P+ D    E    H    +    +    V W    
Sbjct: 815  EEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFEN 870

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPED-SGTYTCRAINELGEAVTSSTLFV 1802
              + +  +   + D     L +  VN ED  G Y C A+N+ G+  TS+ L V
Sbjct: 871  KLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 923



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 5/93 (5%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
            +    P+  T L +   +EG   H    +    +    V WY  NK + S  +F    + 
Sbjct: 830  IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQ 885

Query: 1633 GFVALDIMSCLPED-SGTYTCRAINALGEAVTS 1664
                L I     ED  G Y C A+N  G+  TS
Sbjct: 886  NTYTLVIDKVNTEDHQGEYVCEALNDSGKTATS 918



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 6/102 (5%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I +  P+   PL +     EG  +HL   +    +    V W+   + V    +FK   D
Sbjct: 830  IKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQD 884

Query: 1232 FGFVALDIIHATSAD-TGEYTVRAVNHLGSAHTSAIVRVIER 1272
                 L I    + D  GEY   A+N  G   TSA + V++R
Sbjct: 885  QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 926


>AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein.
          Length = 1019

 Score = 92.3 bits (219), Expect = 4e-17
 Identities = 58/218 (26%), Positives = 98/218 (44%), Gaps = 8/218 (3%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P   ++  N+ +  G  A   V + G P+P++ WF NG  L  S  ++ +   +  +L +
Sbjct: 49  PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
             T+  D G YT +A N  G  + S YL + S  E +         T+T+     + +E 
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKD-------TETES-AVAKSLEK 160

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
                 P F+K  +     +G    F+  V G P P VTWF  ++Q+     + I+ N +
Sbjct: 161 LGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 220

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
           G+   ++ +    DSG+  C A N  GE+     L V+
Sbjct: 221 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVL 258



 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 61/214 (28%), Positives = 96/214 (44%), Gaps = 12/214 (5%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P F     N +++ G +  L   V G     + W  NG  + P    K + +   ++L+I
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA----------PP 4623
            L    +D G+Y C+A N  G+  C A   ++      K   +T++A A          PP
Sbjct: 109  LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK-DTETESAVAKSLEKLGGPCPP 167

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYTLRI 4682
              ++ LK    A+G    F   +VG+P PTV W+K +K +  S Y+ +    +   T  +
Sbjct: 168  HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 227

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            ++   ED G Y C A N  G  T AA+L V   D
Sbjct: 228  NDPQREDSGLYICKAENMLGESTCAAELLVLLED 261



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 68/235 (28%), Positives = 107/235 (45%), Gaps = 17/235 (7%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F K + NA+++ G    L  T+  +  P  +++W+ NG  +     +K  +D    +L
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSL 106

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             IL+   ED G Y C A+N  G+ + ++ +K+++K   + DT  E  + K   LEK   P
Sbjct: 107  IILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--SLEKLGGP 164

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
             P         P FL  L  +    +G  A FE  V  + +P  T+ WF   +++     
Sbjct: 165  CP---------PHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVY 212

Query: 2158 YRTTHD-FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
            Y   H+  G     +     EDSG Y+CKA N LGE+     L V      + DT
Sbjct: 213  YTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 267



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 54/218 (24%), Positives = 91/218 (41%), Gaps = 22/218 (10%)

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
           + +  ++   P F+K   + D++ G +      V G P P++ WF N   +    ++K  
Sbjct: 39  KFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK-F 97

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV---------IEKEQVVA-- 490
           V +  +H+L+I    L D G  TC+A N  G+T     L +          E E  VA  
Sbjct: 98  VFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKS 157

Query: 491 ---------PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR-IH 540
                    P F++    +   +G P +     VG P P +TW K+   +  +     IH
Sbjct: 158 LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIH 217

Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              G+ T  +   +  D+  Y C A+N+ G +   A L
Sbjct: 218 NPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 255



 Score = 81.0 bits (191), Expect = 1e-13
 Identities = 53/209 (25%), Positives = 97/209 (46%), Gaps = 21/209 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P  I+ + +  ++ G     S  ++G P P +QW+    L+ PS  ++     D+++L I
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-----------TQPDQADNLPAL------- 4724
                 EDEG+Y C+A N  G+   +A LK+           T+   A +L  L       
Sbjct: 109  LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168

Query: 4725 --TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIG 4781
                L+ I   +G PA F+  +  +  PT+ W +E   +  +  + +IH  N +   ++ 
Sbjct: 169  FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +   ED+G + C+A    G+   +A+L+V
Sbjct: 229  DPQREDSGLYICKAENMLGESTCAAELLV 257



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 72/276 (26%), Positives = 119/276 (43%), Gaps = 22/276 (7%)

Query: 1796 TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTK 1855
            +SS L  + +     E Q     + ++ L +S  Y  + D E      P FI +++    
Sbjct: 2    SSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKE-GTGPIFIKEVSN-AD 59

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            +S G  A     +   P P  +++W+FNG +L     Y+   D    +L IL    ED G
Sbjct: 60   ISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEG 117

Query: 1916 EYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK-IQYLEDDSRYKRAVQDDSFV 1974
            EYTC A N+ G+ + S  L + SK    +D++ ESA+ K ++ L                
Sbjct: 118  EYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC------------ 165

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD-FG 2033
               P F K +K     +G P   E T+  V +P   V W+   + +     +   ++  G
Sbjct: 166  --PPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNG 221

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                 +     ED+G Y+CKA N +GE+   + + V
Sbjct: 222  SGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 257



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 67/233 (28%), Positives = 101/233 (43%), Gaps = 22/233 (9%)

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIV----PPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
            E    +++     V   K ++  GG++    P   T     V+   G +V L T +T  K
Sbjct: 804  EKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAK 862

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD-SGKYECVAINSAGEARCDAE 4600
              +V W    K V  D + K L++  TYTL+I +   +D  G+Y C A+N +G+    A+
Sbjct: 863  --EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAK 920

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              V             +AA      IEPL+   VA G   +F+C+I   P    QW+K  
Sbjct: 921  LTVV-----------KRAAPVIKRKIEPLE---VALGHLAKFTCEIQSAPNVRFQWFKAG 966

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            + I  S    +  +    +L I      D G+Y C A N  G V+  A L VT
Sbjct: 967  REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 1019



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 73/256 (28%), Positives = 109/256 (42%), Gaps = 24/256 (9%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            E L+ L +S V       E+E G  P+F   +SN + +  G+ A     +T    P  K+
Sbjct: 25   ETLELLSESPVYPTKFDSEKE-GTGPIFIKEVSNAD-ISMGDVATLS--VTVIGIPKPKI 80

Query: 3455 EWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            +W++NG  L   + ++   D     L I  T  ED GEY C A N+YG+ + +A +K+  
Sbjct: 81   QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 140

Query: 3515 KRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSS 3574
            K     E       E  + K  +LE   G             PP F      +  ++   
Sbjct: 141  KG----EGHKDTETESAVAK--SLEKLGGPC-----------PPHFLKELKPIRCAQGLP 183

Query: 3575 AHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI-NDFGFVILEIGGVYQRDAGLYTCK 3633
            A FE  +  V + +  V WF   K L T      I N  G     +    + D+GLY CK
Sbjct: 184  AIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICK 241

Query: 3634 ATNRHGEATVSCKLQV 3649
            A N  GE+T + +L V
Sbjct: 242  AENMLGESTCAAELLV 257



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 68/231 (29%), Positives = 101/231 (43%), Gaps = 19/231 (8%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            + +G  P F   + N + +  G  A    TV+ +  P  KI+W+ NG  +  S   K V 
Sbjct: 43   EKEGTGPIFIKEVSNAD-ISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVF 99

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRE 3262
            D     L I +T+  D GEY C A N YG+    A +    KG  + ++    ++AK   
Sbjct: 100  DGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--S 157

Query: 3263 LESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNG 3322
            LE L G     P      PP F+ +++ + +  +G  A FE  +  V +P   V WF   
Sbjct: 158  LEKLGG-----PC-----PPHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKEN 204

Query: 3323 KKLPHGHRYRTFHD-FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            K+L     Y   H+  G     +     E+SG Y C A N LG  +  A L
Sbjct: 205  KQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 255



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 73/237 (30%), Positives = 101/237 (42%), Gaps = 16/237 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI+WF NGV LT  A  K  FD    +L I   + +D G YTC A+N  G+ + +A 
Sbjct: 76   PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAY 135

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            +KI  +    GE  H D+ +   A+                   F+  L  I C +G   
Sbjct: 136  LKINSK----GEG-HKDT-ETESAVAKSLEKLGGPCPPH-----FLKELKPIRCAQGLPA 184

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH-TYEEDSGIYTCKA 2850
             FE  V     PT  + WF  NK L +   Y   H+ +     I +    EDSG+Y CKA
Sbjct: 185  IFEYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKA 242

Query: 2851 TNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTE 2907
             N  G +T +  L    +     DT   + K+  EA E   +  L KG      D+E
Sbjct: 243  ENMLGESTCAAELLVLLEDTDMTDTP-CKAKSTPEAPEDFPQTPL-KGPAVEALDSE 297



 Score = 76.2 bits (179), Expect = 3e-12
 Identities = 56/189 (29%), Positives = 83/189 (43%), Gaps = 6/189 (3%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I  PL D +  EG  +  +  I       V WY  +KL+   + F+  +  + YTL I
Sbjct: 835  PMIHTPLVDTVSEEGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNTYTLVI 892

Query: 4683 SEAFPED-EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
             +   ED +G+Y C A N +G+   +AKL V +         + PL    V  G  A+F 
Sbjct: 893  DKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLE---VALGHLAKFT 949

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +I S      QW + G  I E+    +      + L I  T   D G +TC+A+   G 
Sbjct: 950  CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 1009

Query: 4802 VETSAKLVV 4810
            V  +A L V
Sbjct: 1010 VSCTATLTV 1018



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 71/267 (26%), Positives = 105/267 (39%), Gaps = 27/267 (10%)

Query: 4395 QTQERVVEGPVKPSK--------PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            +T E + E PV P+K         PIF K++    +   + A   V   G P P I+W+ 
Sbjct: 25   ETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFF 84

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ 4506
                +  S D++         LII    +ED   +  +A N  G   CSA L +  K   
Sbjct: 85   NGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEG 144

Query: 4507 GR---------------GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
             +               GG  PP F    + +    G     +  V G     V W K  
Sbjct: 145  HKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKEN 204

Query: 4552 KKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT-- 4608
            K++   +   I+   +G+ T ++ +   +DSG Y C A N  GE+ C AE +V L  T  
Sbjct: 205  KQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDM 264

Query: 4609 KDKPKPQTKAANAPPEIIE-PLKDKIV 4634
             D P        AP +  + PLK   V
Sbjct: 265  TDTPCKAKSTPEAPEDFPQTPLKGPAV 291



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 63/237 (26%), Positives = 106/237 (44%), Gaps = 19/237 (8%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P+F   + +  ++    A     +I  G PK +++W  NGV +  S     + D    +L
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTVI--GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSL 106

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             + +   ED G YTC A N+ G+ + S+ L + SK     +++ ESA+ K   LE     
Sbjct: 107  IILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--SLE----- 159

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
                  ++     P F+ +L  P + ++G  A +E  +   P P   V W+   K L + 
Sbjct: 160  ------KLGGPCPPHFLKELK-PIRCAQGLPAIFEYTVVGEPAPT--VTWFKENKQLCTS 210

Query: 1891 HRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946
              Y    N  G     +     EDSG Y CKA N LG++  +  L V  +++ + D+
Sbjct: 211  VYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 267



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 74/284 (26%), Positives = 122/284 (42%), Gaps = 21/284 (7%)

Query: 2064 TSSVKVDAKSGLYLDTLDEQRLKKIQEL--EKYERPKPIEEEQPGQRPVFLTALTSLENL 2121
            +SS     + GL+   L   ++ +  EL  E    P   + E+ G  P+F+  +++ + +
Sbjct: 2    SSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-I 60

Query: 2122 KEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT 2181
              GD A     V  I  P   I WF NG  +     Y+   D    +L IL+T  ED G 
Sbjct: 61   SMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGE 118

Query: 2182 YMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISP 2241
            Y C A+N  G+ + +  LK+        DT+  + + K   LE  G             P
Sbjct: 119  YTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK--SLEKLGGP----------CP 166

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD-FGYV 2300
            P F+ EL+      +G  A FE  V  V +P   + ++   K L ++  + I  +  G  
Sbjct: 167  PHFLKELK-PIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 223

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344
            +  +     ED+G Y  KA N LG  T A  + V  + + ++++
Sbjct: 224  TFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDT 267



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 64/232 (27%), Positives = 95/232 (40%), Gaps = 24/232 (10%)

Query: 3011 ERTQHPKGTEGLE--KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHY 3068
            E +    GTE +   KIQ  E  L KE G          P   T   D V   EG I H 
Sbjct: 806  EESSSESGTEEVATVKIQEAEGGLIKEDG----------PMIHTPLVDTVS-EEGDIVHL 854

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD-SGTYSCRATN 3127
              S+    +    + W++  K + +  + + +       L I    T D  G Y C A N
Sbjct: 855  TTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALN 910

Query: 3128 KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187
              G+   S KL  V ++    P     I+ +E +  G  A F C +     P+++ +W+ 
Sbjct: 911  DSGKTATSAKLTVVKRAA---PVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFK 964

Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
             G+ +  S +    S      L+I  TQ  D GEY C+A N+YG     AT+
Sbjct: 965  AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 1016



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 66/275 (24%), Positives = 115/275 (41%), Gaps = 19/275 (6%)

Query: 1130 SASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPV 1189
            S+S        + ++ +      +T  +     V P     E   + P+F++ +SN   +
Sbjct: 2    SSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-I 60

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGE 1249
            S G    L   +  +G P  +++WF NG  +T  + +K  +D    +L I+     D GE
Sbjct: 61   SMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGE 118

Query: 1250 YTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            YT  A N  G    SA +++  + +   DT+ E A+             K + E +    
Sbjct: 119  YTCMASNDYGKTICSAYLKINSKGEGHKDTETESAV------------AKSL-EKLGGPC 165

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
             P F + L  I   +G     E  +  VG+    V WF   K + T   +   +  +   
Sbjct: 166  PPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 223

Query: 1370 LDLLS-VYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
              +++    EDSG+Y C+A N LGE+  +  L V+
Sbjct: 224  TFIVNDPQREDSGLYICKAENMLGESTCAAELLVL 258



 Score = 68.1 bits (159), Expect = 7e-10
 Identities = 48/175 (27%), Positives = 72/175 (41%), Gaps = 7/175 (4%)

Query: 405  EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVV 463
            EG +      +T     EV W+  ++ +  D   K L +++  + L+I  V   D  G  
Sbjct: 848  EGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEY 904

Query: 464  TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
             C A N SG+TA   +L V+++    AP    +   L V  G            P  R  
Sbjct: 905  VCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQ 961

Query: 524  WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            W K G  I  + +  I +    S+L+I R +  D   Y C A N  GS +  A L
Sbjct: 962  WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 1016



 Score = 67.7 bits (158), Expect = 1e-09
 Identities = 65/235 (27%), Positives = 105/235 (44%), Gaps = 25/235 (10%)

Query: 2234 VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHD--------PNLRIEFYHNGKAL 2285
            + E  + P +F +E  GT  +F  + ++ +  +  V          P  +I+++ NG  L
Sbjct: 30   LSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLL 89

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQ 2345
              +A +   FD    SL I     ED GEY+  A N  G    +  + + +KG       
Sbjct: 90   TPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG------- 142

Query: 2346 RPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGD 2405
              EG  K  E ESA      ++  P     P F + L+ I    +G  A F+  +  VG+
Sbjct: 143  --EG-HKDTETESAVAKSLEKLGGPCP---PHFLKELKPI-RCAQGLPAIFEYTV--VGE 193

Query: 2406 PTLKVEWFRNEKLIEDSSRITKTHD-FGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            P   V WF+  K +  S   T  H+  G  +  ++  + ED G+Y+C+A N+LGE
Sbjct: 194  PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGE 248



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 65/251 (25%), Positives = 105/251 (41%), Gaps = 19/251 (7%)

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
            E +++L + S  + T    E     PI    + N +I  G  A     +I +     K++
Sbjct: 25   ETLELLSE-SPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP--KIQ 81

Query: 1613 WYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            W+ N   L   + +    +    +L I+    ED G YTC A N  G+ + S    ++SK
Sbjct: 82   WFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSK 141

Query: 1673 KSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEA 1732
               + +++ E A+ +   LE                  P F   +K IR A+   A FE 
Sbjct: 142  GEGHKDTETESAVAK--SLEKLGG-----------PCPPHFLKELKPIRCAQGLPAIFEY 188

Query: 1733 RLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD-FGYVALNMKYVNPEDSGTYTCRAINEL 1791
             +  VG+P   V W +    +  S   T +H+  G     +     EDSG Y C+A N L
Sbjct: 189  TV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENML 246

Query: 1792 GEAVTSSTLFV 1802
            GE+  ++ L V
Sbjct: 247  GESTCAAELLV 257



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 59/211 (27%), Positives = 92/211 (43%), Gaps = 19/211 (9%)

Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET 722
           +G P  KI+W  NG  +  S+ +  +F     SL +L   ++D GEYTC A +  G    
Sbjct: 73  IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTIC 132

Query: 723 KAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQ-RPQFIRPLQDLGE 781
            A L +  +        H +T       E  S     +S+E+      P F++ L+ +  
Sbjct: 133 SAYLKINSKG-----EGHKDT-------ETESAVA--KSLEKLGGPCPPHFLKELKPI-R 177

Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGYVSLNIMHLRAEDA 840
             +G  A FE   T V +P   V W+K+ + +  S   T I N  G  +  +   + ED+
Sbjct: 178 CAQGLPAIFE--YTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDS 235

Query: 841 GSYTVRAVNKLGEAISTASIRVAARSTVTAD 871
           G Y  +A N LGE+   A + V    T   D
Sbjct: 236 GLYICKAENMLGESTCAAELLVLLEDTDMTD 266



 Score = 63.7 bits (148), Expect = 2e-08
 Identities = 66/269 (24%), Positives = 108/269 (40%), Gaps = 29/269 (10%)

Query: 3788 SAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGV 3847
            SA+ + +  ++L      E ++ L    +     +     T P FI ++ +  +   +  
Sbjct: 7    SAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVA 66

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
                 V     PK +I+W+ NG LL     Y+ V+D    SL IL+   ED GEY C A 
Sbjct: 67   TLSVTVIGI--PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMAS 124

Query: 3908 NDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDV 3967
            ND+G+    A +           N    G K +E  + +  +++K               
Sbjct: 125  NDYGKTICSAYLKI---------NSKGEGHKDTETESAVAKSLEKLGGPC---------- 165

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
                PP F+ +++       +    FE  +  VG+P   V WF   K L     +T I++
Sbjct: 166  ----PPHFLKELKPIRCAQGLPAI-FEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHN 218

Query: 4028 -FGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
              G           EDSG Y+C+A N+ G
Sbjct: 219  PNGSGTFIVNDPQREDSGLYICKAENMLG 247



 Score = 62.1 bits (144), Expect = 5e-08
 Identities = 68/244 (27%), Positives = 100/244 (40%), Gaps = 34/244 (13%)

Query: 3022 LEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI--VDISEGQIAHYEASLIPTGDQS 3079
            L KI    + L + P      D+ +        K++   DIS G +A    ++I  G   
Sbjct: 20   LSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVI--GIPK 77

Query: 3080 MVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
              I+WF+NG  +  S   + V+      L IL TK  D G Y+C A+N +G+   S  L+
Sbjct: 78   PKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLK 137

Query: 3140 CVDKSKGQK--------------------PRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
               K +G K                    P F   ++ I     G  A FE TV  V +P
Sbjct: 138  INSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIR-CAQGLPAIFEYTV--VGEP 194

Query: 3180 DMKIEWYHNGQPMRHS---TRIKTVSDFG-FVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               + W+   + +  S   T I   +  G F+V D    Q  DSG Y+C+A N  GE   
Sbjct: 195  APTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVND---PQREDSGLYICKAENMLGESTC 251

Query: 3236 RATI 3239
             A +
Sbjct: 252  AAEL 255



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 65/254 (25%), Positives = 98/254 (38%), Gaps = 24/254 (9%)

Query: 3672 IQKLEETLHKREEITI-----EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPT 3726
            + K+ ETL    E  +     + EK       ++   N D+  G        V  +G P 
Sbjct: 20   LSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTV--IGIPK 77

Query: 3727 MRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             +I WF NG      +    + D    +L I +    D GEYTC A+N +G      K  
Sbjct: 78   PKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYG------KTI 131

Query: 3787 CSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846
            CSA   I           GE  K+ E         E+     PP F+ ++K     +   
Sbjct: 132  CSAYLKI--------NSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLP 183

Query: 3847 VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICR 3905
              FE  V  +  P   + W++  K L +   Y  +++  G  +  +     EDSG YIC+
Sbjct: 184  AIFEYTVVGEPAPT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICK 241

Query: 3906 AVNDFGEDFTKATI 3919
            A N  GE    A +
Sbjct: 242  AENMLGESTCAAEL 255



 Score = 59.7 bits (138), Expect = 3e-07
 Identities = 64/238 (26%), Positives = 93/238 (39%), Gaps = 20/238 (8%)

Query: 2355 ELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR 2414
            EL S  P    +         P+F + + N D I  G  A     +I  G P  K++WF 
Sbjct: 28   ELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTVI--GIPKPKIQWFF 84

Query: 2415 NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXI 2474
            N  L+  S+      D    S+ I   + EDEG Y C ASN  G+               
Sbjct: 85   NGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEG 144

Query: 2475 QLETQHPEGM-KKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVV 2533
              +T+    + K ++KL  P              P F + L  P    +G  A +E  V 
Sbjct: 145  HKDTETESAVAKSLEKLGGPC------------PPHFLKELK-PIRCAQGLPAIFEYTV- 190

Query: 2534 PVGDPSLRFEWYINGVELKMGSRFRTTHD-FGFVTLDINSVVANDAGLYMCKAINRAG 2590
             VG+P+    W+    +L     +   H+  G  T  +N     D+GLY+CKA N  G
Sbjct: 191  -VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG 247



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 67/261 (25%), Positives = 101/261 (38%), Gaps = 28/261 (10%)

Query: 3257 LAKIRELESLQGAQQQTPSTPSAEP----PKFITQIQDVTKLVEGQSAHFEARLVPVDDP 3312
            L+KI E   L       P+   +E     P FI ++ +   +  G  A     ++ +  P
Sbjct: 20   LSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNAD-ISMGDVATLSVTVIGIPKP 78

Query: 3313 DLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              K++WF+NG  L     Y+   D     L IL+   E+ GEY C+A+N  G+    A L
Sbjct: 79   --KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYL 136

Query: 3373 KCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENL 3432
            K  SK     D++    +   LEKL                   G  P   +        
Sbjct: 137  KINSKGEGHKDTETESAVAKSLEKL------------------GGPCPPHFLKELKPIRC 178

Query: 3433 REGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD-FGFVILEISPTYPEDSG 3491
             +G  A FE   T   +P   V W+   K L     +    +  G     ++    EDSG
Sbjct: 179  AQGLPAIFE--YTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 236

Query: 3492 EYLCRAYNNYGEAVTTASMKV 3512
             Y+C+A N  GE+   A + V
Sbjct: 237  LYICKAENMLGESTCAAELLV 257



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 68/258 (26%), Positives = 103/258 (39%), Gaps = 29/258 (11%)

Query: 3532 IDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV 3591
            I++   L   S    T     + G  P F    S+  +S    A     +I +     ++
Sbjct: 23   INETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGI--PKPKI 80

Query: 3592 EWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            +WF NG  L   +  K + D     L I      D G YTC A+N +G+   S  L++  
Sbjct: 81   QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 140

Query: 3652 RQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGG 3711
            +           H  + TES   + ++L K          P PP F  E+K  I   +G 
Sbjct: 141  KG--------EGHKDTETES--AVAKSLEKL-------GGPCPPHFLKELKP-IRCAQGL 182

Query: 3712 PVHFDCRVEPVGDPTMRIDWFHNGRPFATG---SRVHTLNDFG-FIALDIDYIYARDAGE 3767
            P  F+  V  VG+P   + WF   +   T    + +H  N  G FI  D       D+G 
Sbjct: 183  PAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQ---REDSGL 237

Query: 3768 YTCRATNKWGSATTTAKI 3785
            Y C+A N  G +T  A++
Sbjct: 238  YICKAENMLGESTCAAEL 255



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 58/229 (25%), Positives = 94/229 (41%), Gaps = 27/229 (11%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + + N +   G    L   +  +G    +++WF NG  +     ++  ++ D  +L
Sbjct: 49   PIFIKEVSNADISMGDVATLSVTV--IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSL 106

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK----KDLILESQHPSGLEKIQYLED 1426
             +L    ED G YTC A+N  G+ + S  L++ +K    KD   ES     LEK+     
Sbjct: 107  IILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKL----- 161

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
                             P F+   K I    +G    FE  +  V +    V WFK  + 
Sbjct: 162  ------------GGPCPPHFLKELKPI-RCAQGLPAIFEYTV--VGEPAPTVTWFKENKQ 206

Query: 1487 VTIGHRFRPIHD-FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            +     +  IH+  G     + D   EDSG+Y C+A N++G    +  L
Sbjct: 207  LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 255



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 44/148 (29%), Positives = 67/148 (45%), Gaps = 13/148 (8%)

Query: 211 NGTDHSSTDDFKV--DTFEYRLLREVSFRESITKRYV-------GESDVQISTEIDRSL- 260
           +G DHS    F    D  EY  +    + ++I   Y+       G  D +  + + +SL 
Sbjct: 100 DGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLE 159

Query: 261 --GPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
             G   PP   ++ +  +  +G  A F+  + G P P VTWFK  ++L  S  + II   
Sbjct: 160 KLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNP 219

Query: 319 NHT-TLRVRNTQKSDSGHYTLLAENPNG 345
           N + T  V + Q+ DSG Y   AEN  G
Sbjct: 220 NGSGTFIVNDPQREDSGLYICKAENMLG 247



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 5/125 (4%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            +I  K    + TE E         + GP     PP F K+++P R  +   A FE    G
Sbjct: 137  KINSKGEGHKDTETESAVAKSLEKLGGPC----PPHFLKELKPIRCAQGLPAIFEYTVVG 192

Query: 4437 EPLPLIKWYRENFPIKNSPDFQ-IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            EP P + W++EN  +  S  +  IH  +     I+     EDS ++   AEN  G + C+
Sbjct: 193  EPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCA 252

Query: 4496 ANLVV 4500
            A L+V
Sbjct: 253  AELLV 257



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 75/299 (25%), Positives = 109/299 (36%), Gaps = 28/299 (9%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            +FI  ++N     GD       V     P  KI+WFFN   L     YK   D    SL 
Sbjct: 50   IFIKEVSNADISMGDVATLSVTVIGIPKP--KIQWFFNGVLLTPSADYKFVFDGDDHSLI 107

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I  T  ED G YTC A+N  G    S  L+       + DT+               E+ 
Sbjct: 108  ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTE--------------TESA 153

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
            +AK    S+     P P   +      +  +G     E  V    +P   + W+   K L
Sbjct: 154  VAK----SLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQL 207

Query: 2955 EQGSRFKLT-SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERT 3013
                 + +  +  G  T  + D    DSG+Y CKA N  GE+  ++ +    +D   + T
Sbjct: 208  CTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDT--DMT 265

Query: 3014 QHP-KGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFT--TVFKDIVDISEGQIAHYE 3069
              P K     E  ++   +  K P  +  D       F   T+ K  +   E Q   YE
Sbjct: 266  DTPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYE 324



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 36/114 (31%), Positives = 49/114 (42%), Gaps = 2/114 (1%)

Query: 49  TTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK 108
           T ++ S     P       E + PIF +   NA  + G  A     + G P P + W   
Sbjct: 26  TLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFN 85

Query: 109 KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
              L     Y   ++    D SL+I      DEGEYTC A N YG+ ICS Y++
Sbjct: 86  GVLLTPSADYKFVFDGD--DHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLK 137



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 1/92 (1%)

Query: 67  GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
           G P PP F +  K  R AQG  A FE  + G P P V+W ++   L     Y++ +N   
Sbjct: 162 GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHN-PN 220

Query: 127 GDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
           G  + ++      D G Y C A N  GE+ C+
Sbjct: 221 GSGTFIVNDPQREDSGLYICKAENMLGESTCA 252



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 56/207 (27%), Positives = 87/207 (42%), Gaps = 24/207 (11%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  KI+W+FNG +L   + +K   D    +L ++     D G YTC A N  G+   S+ 
Sbjct: 76   PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAY 135

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
            +   SK          +G +  E    +  SL K  G         PP F    K I   
Sbjct: 136  LKINSKG---------EGHKDTETESAVAKSLEKLGGP-------CPPHFLKELKPI-RC 178

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGTKTTDSG 3119
            ++G  A +E +++  G+ +  + WF   K +  S     ++   G     +   +  DSG
Sbjct: 179  AQGLPAIFEYTVV--GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 236

Query: 3120 TYSCRATNKWGQ----AEISVKLECVD 3142
             Y C+A N  G+    AE+ V LE  D
Sbjct: 237  LYICKAENMLGESTCAAELLVLLEDTD 263



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 58/242 (23%), Positives = 103/242 (42%), Gaps = 31/242 (12%)

Query: 3943 LTQMEATIKKYT-SEVYLTEDDLYDVDKKQP-PRFVTQIQS-QTSLVEMETTKFECQLAP 3999
            L+++  T++  + S VY T+   +D +K+   P F+ ++ +   S+ ++ T      +  
Sbjct: 20   LSKINETLELLSESPVYPTK---FDSEKEGTGPIFIKEVSNADISMGDVATLS----VTV 72

Query: 4000 VGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDET 4059
            +G P  K++WFFNG  L     +  ++D    ++   +   ED GEY C A+N YG    
Sbjct: 73   IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTIC 132

Query: 4060 KAVIKTTGKPGIVYDSQLPKHM-KSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPD 4118
             A +K   K     D++    + KS+EK+                     CPP F+    
Sbjct: 133  SAYLKINSKGEGHKDTETESAVAKSLEKL------------------GGPCPPHFLKELK 174

Query: 4119 AVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFDIPKTRQYD 4176
             +   +G  A F   V G P P V W      +     Y + +  +G   F +   ++ D
Sbjct: 175  PIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQRED 234

Query: 4177 TG 4178
            +G
Sbjct: 235  SG 236



 Score = 53.6 bits (123), Expect = 2e-05
 Identities = 57/245 (23%), Positives = 93/245 (37%), Gaps = 20/245 (8%)

Query: 2491 EQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVE 2550
            E P      + ++E   PIF + ++  +++  G  A     V+  G P  + +W+ NGV 
Sbjct: 32   ESPVYPTKFDSEKEGTGPIFIKEVSN-ADISMGDVATLSVTVI--GIPKPKIQWFFNGVL 88

Query: 2551 LKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQA 2610
            L   + ++   D    +L I      D G Y C A N  G                    
Sbjct: 89   LTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS-------- 140

Query: 2611 MRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRT 2670
             + E  +  + + A    + ++    G    P F   LK   +  +G     E  V    
Sbjct: 141  -KGEGHKDTETESAVAKSLEKL----GGPCPPHFLKELKPI-RCAQGLPAIFEYTVVGEP 194

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFD-FGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729
             P   + WFK    L T        +  G  T  +N  + +DSG+Y CKA N+LGE+   
Sbjct: 195  APT--VTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCA 252

Query: 2730 ASIKI 2734
            A + +
Sbjct: 253  AELLV 257



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 53/194 (27%), Positives = 80/194 (41%), Gaps = 16/194 (8%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            K++WF NG  +T    ++ + D    +L I+    ED G YTC A N  G    S  L  
Sbjct: 79   KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 138

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
             S  +  + T+ E+ +   + LE                  P     LK +   +G  A 
Sbjct: 139  NSKGEGHKDTETESAV--AKSLEKLG-----------GPCPPHFLKELKPIRCAQGLPAI 185

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN-FGFVALDIMSCLPEDSGTYTCRAI 1655
            FE  +  V +    V W+  NK L +   +T  +N  G     +     EDSG Y C+A 
Sbjct: 186  FEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAE 243

Query: 1656 NALGEAVTSGIAIV 1669
            N LGE+  +   +V
Sbjct: 244  NMLGESTCAAELLV 257



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 49/210 (23%), Positives = 88/210 (41%), Gaps = 22/210 (10%)

Query: 794  LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
            +T +  P  +++W+ +G  +T S+    +F+    SL I+  + ED G YT  A N  G+
Sbjct: 70   VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGK 129

Query: 854  AISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKT 913
             I +A +++ ++     D    E    + K+                        P F  
Sbjct: 130  TICSAYLKINSKGEGHKD---TETESAVAKSLEKLG---------------GPCPPHFLK 171

Query: 914  PIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN-FGYVALTIK 972
             +K  I   +G  A FE  +  +G+    V W K+ + +  S   T   N  G     + 
Sbjct: 172  ELK-PIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
                 D+G Y C+A N +G++T +A L ++
Sbjct: 229  DPQREDSGLYICKAENMLGESTCAAELLVL 258



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 26/79 (32%), Positives = 40/79 (50%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G  A     +    KP IQW   G L+  + D++ + +G++  L+I  T  ED G +TC 
Sbjct: 63   GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 122

Query: 4795 ATTAAGQVETSAKLVVKSK 4813
            A+   G+   SA L + SK
Sbjct: 123  ASNDYGKTICSAYLKINSK 141



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 14/128 (10%)

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866
            KI+E E G I +   + P++ TP      +     EE + V     +   ++    + WY
Sbjct: 821  KIQEAEGGLIKE---DGPMIHTP------LVDTVSEEGDIVHLTTSITNAKE----VNWY 867

Query: 3867 RNGKLLPSGHRYRTVYDMGFVSLDILYVYAED-SGEYICRAVNDFGEDFTKATISCKKLP 3925
               KL+PS  +++ + D    +L I  V  ED  GEY+C A+ND G+  T A ++  K  
Sbjct: 868  FENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 927

Query: 3926 DIILQNQV 3933
              +++ ++
Sbjct: 928  APVIKRKI 935



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L + V +EGD +H   ++  +++    + W+F NK +PS  ++K   D +  +L I    
Sbjct: 841  LVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVN 896

Query: 2840 EED-SGIYTCKATNSKGSATTSGSL 2863
             ED  G Y C+A N  G   TS  L
Sbjct: 897  TEDHQGEYVCEALNDSGKTATSAKL 921



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 3/115 (2%)

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            + L DS +      + V    AP    ++  P +++ G  A + C I+  P  N+R +W+
Sbjct: 907  EALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSAP--NVRFQWF 963

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
              G+ +    +    +    ++L+IL     D GEYTCKA N  G    +  L V
Sbjct: 964  KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 2/82 (2%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            ++V  G    F C ++    P +R  WF  GR      +    +     +L+I      D
Sbjct: 938  LEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVD 995

Query: 3765 AGEYTCRATNKWGSATTTAKIT 3786
             GEYTC+A+N++GS + TA +T
Sbjct: 996  CGEYTCKASNEYGSVSCTATLT 1017



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 13/135 (9%)

Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGP--------TKLSEGQSA 1862
            E Q ES     ++ E SS     E   V + +A   + + +GP        T   EG   
Sbjct: 793  EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIV 852

Query: 1863 HYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED-SGEYTCKA 1921
            H    I    + N    WYF  K++ S  +++   D     L I  V  ED  GEY C+A
Sbjct: 853  HLTTSITNAKEVN----WYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEA 908

Query: 1922 INNLGQAVSSIRLNV 1936
            +N+ G+  +S +L V
Sbjct: 909  LNDSGKTATSAKLTV 923



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 38/164 (23%), Positives = 60/164 (36%), Gaps = 9/164 (5%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVV 4500
            + WY EN  + +   F+         L+I +V  ED    +   A N  G    SA L V
Sbjct: 864  VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 923

Query: 4501 EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN 4560
             ++          P      + + V  G L +   ++     +   W K G+++    + 
Sbjct: 924  VKR--------AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 975

Query: 4561 KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
             I       +L IL     D G+Y C A N  G   C A   V+
Sbjct: 976  SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 1019



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 6/131 (4%)

Query: 734  IERTSQHPETLQYI-QQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEA 792
            I++ +      +Y+ + L D  K      +       P   R ++ L E+  G  A F  
Sbjct: 892  IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPL-EVALGHLAKFTC 950

Query: 793  QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKL 851
            ++   S P +R +W+K GR I  S +  SI +  Y+ SL I+  +  D G YT +A N+ 
Sbjct: 951  EIQ--SAPNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 1007

Query: 852  GEAISTASIRV 862
            G    TA++ V
Sbjct: 1008 GSVSCTATLTV 1018



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 52/201 (25%), Positives = 84/201 (41%), Gaps = 17/201 (8%)

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            IG    +++W  +G  +  S+     F+    +L I    + D G YTC A N  G+   
Sbjct: 73   IGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTIC 132

Query: 996  SANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKI 1055
            SA L I +K +   +++    + K             + E++     P FL  LK   + 
Sbjct: 133  SAYLKINSKGEGHKDTETESAVAK-------------SLEKLGGPCPPHFLKELKPI-RC 178

Query: 1056 VEGQSAHFEARVEPQSDLTMTVEWYFNGKQI-TSANRIQTYHDFGYVALDIASVRAEDSG 1114
             +G  A FE  V    +   TV W+   KQ+ TS      ++  G     +   + EDSG
Sbjct: 179  AQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 236

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
            +Y   A N  GE+  +A + V
Sbjct: 237  LYICKAENMLGESTCAAELLV 257



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/90 (30%), Positives = 43/90 (47%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I +K    ++  G  A+F  ++   P  R  WFK G+ +  S+K  I ++   ++L +
Sbjct: 929  PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 988

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
              TQ  D G YT  A N  G +  +  L V
Sbjct: 989  LRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 2/87 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P+ ++  +    A G  AKF  +++  P     W +    + E +K S+R ++    + +
Sbjct: 929  PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 988

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICS 158
            L  Q+   D GEYTC A N+YG   C+
Sbjct: 989  LRTQVV--DCGEYTCKASNEYGSVSCT 1013



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 43/165 (26%), Positives = 64/165 (38%), Gaps = 9/165 (5%)

Query: 3351 NSGEYECVATNKLGRDSTKANLKCTSKEN---LILDSQLPRGMEGGLEKLQTLEDSMVRR 3407
            N+ E      NKL     K   KC   +N   L++D       +G     + L DS    
Sbjct: 860  NAKEVNWYFENKLVPSDEK--FKCLQDQNTYTLVIDKVNTEDHQGEYV-CEALNDSGKTA 916

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
                +   K  APV    +  +E +  G  A F   +     PN++ +W+  G+ +    
Sbjct: 917  TSAKLTVVKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESD 973

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            +           LEI  T   D GEY C+A N YG    TA++ V
Sbjct: 974  KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PV    +  LE +  G  A F C ++  + P++   WF  G++I    +          +
Sbjct: 929  PVIKRKIEPLE-VALGHLAKFTCEIQ--SAPNVRFQWFKAGREIYESDKCSIRSSKYISS 985

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L+IL T   D G Y CKA+N+ G    T TL V
Sbjct: 986  LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 2/125 (1%)

Query: 1278 DTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPV 1337
            +T++ Q     + L D+ +     +  +    AP   R +  +E   G      C +Q  
Sbjct: 896  NTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA 955

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
             +  +R +WF  G+ I    +          +L++L     D G YTC+A+N+ G    +
Sbjct: 956  PN--VRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT 1013

Query: 1398 CALRV 1402
              L V
Sbjct: 1014 ATLTV 1018



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 29/130 (22%), Positives = 57/130 (43%), Gaps = 4/130 (3%)

Query: 3793 IVLESQLPQGMSGEKIKEL--ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850
            +V++    +   GE + E   + G+ + + K   +    P    +I+   V      +F 
Sbjct: 890  LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFT 949

Query: 3851 CRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910
            C ++    P +R +W++ G+ +    +          SL+IL     D GEY C+A N++
Sbjct: 950  CEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 1007

Query: 3911 GEDFTKATIS 3920
            G     AT++
Sbjct: 1008 GSVSCTATLT 1017



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 1691 LEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            L D+ K    +    V   APV    ++ + VA    A F   +     P +R +W + G
Sbjct: 909  LNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAG 966

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
              I  S++ +        +L +      D G YTC+A NE G    ++TL V
Sbjct: 967  REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 29/128 (22%), Positives = 51/128 (39%), Gaps = 2/128 (1%)

Query: 4081 MKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKP 4140
            +  I +  E+ +   V P +   E K    P+F+       +  G+ A     V G PKP
Sbjct: 20   LSKINETLELLSESPVYPTKFDSE-KEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKP 78

Query: 4141 RVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199
            ++ W  NG  +   + YK  +DG  H   I  T+  D G+   +             LK+
Sbjct: 79   KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 138

Query: 4200 IPRHDDYR 4207
              + + ++
Sbjct: 139  NSKGEGHK 146



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYIS-LDMLSLNIQDSGEYTCRAVSATGVAETKA 724
            P ++ +W K G+ I  S +  SI    YIS L++L   + D GEYTC+A +  G     A
Sbjct: 956  PNVRFQWFKAGREIYESDK-CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 1014

Query: 725  VLHVT 729
             L VT
Sbjct: 1015 TLTVT 1019



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 6/145 (4%)

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK-PQFGKPIK 1985
            + V+S  ++ + ++  ++ S+ +         E+ +  K    +   + E  P    P+ 
Sbjct: 783  KGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLV 842

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            +    EG  VHL  ++T   +    V WY   + V    +FK   D     L I     E
Sbjct: 843  DTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE 898

Query: 2046 D-TGTYMCKATNAVGEAVTTSSVKV 2069
            D  G Y+C+A N  G+  T++ + V
Sbjct: 899  DHQGEYVCEALNDSGKTATSAKLTV 923



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 4/123 (3%)

Query: 1147 HRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGD 1206
            H+G Y     + +S       ++  + ++ PV  + +  P  V+ G      C ++    
Sbjct: 900  HQGEYV-CEALNDSGKTATSAKLTVVKRAAPVIKRKIE-PLEVALGHLAKFTCEIQSA-- 955

Query: 1207 PTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAI 1266
            P +R +WF  GR +    +          +L+I+     D GEYT +A N  GS   +A 
Sbjct: 956  PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 1015

Query: 1267 VRV 1269
            + V
Sbjct: 1016 LTV 1018



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P  K  I + + +  G  A F   ++   +  +R +W K GR +  S + +   +    +
Sbjct: 929  PVIKRKI-EPLEVALGHLAKFTCEIQSAPN--VRFQWFKAGREIYESDKCSIRSSKYISS 985

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I    V D G YTC+A N  G  + +A LT+
Sbjct: 986  LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 6/97 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P   TP+ D +S +EG   H    +     +   V W  + + V +  +     +     
Sbjct: 835  PMIHTPLVDTVS-EEGDIVHLTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYT 889

Query: 969  LTIKSVTVHD-AGHYTCRAYNAIGQATTSANLTIVTK 1004
            L I  V   D  G Y C A N  G+  TSA LT+V +
Sbjct: 890  LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 926



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            G  A F C+++    PN+R +++  G+ +  + +  I       SL+I      D GEY+
Sbjct: 943  GHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 1000

Query: 2317 VKAINALGHCTSAISMTVT 2335
             KA N  G  +   ++TVT
Sbjct: 1001 CKASNEYGSVSCTATLTVT 1019



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 43/204 (21%), Positives = 82/204 (40%), Gaps = 17/204 (8%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            ++W+FNG  +T +   +   D    +L I   + ED G YT +A N  G+   SA + + 
Sbjct: 80   IQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKIN 139

Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196
            ++          G  +       +K +E +          P F++ L    P+   + + 
Sbjct: 140  SKG--------EGHKDTETESAVAKSLEKLG-----GPCPPHFLKELK---PIRCAQGLP 183

Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIH-ATSADTGEYTVRAV 1255
                   +G+P   V WF   + +     +   ++       I++     D+G Y  +A 
Sbjct: 184  AIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAE 243

Query: 1256 NHLGSAHTSAIVRVIERSDIVTDT 1279
            N LG +  +A + V+     +TDT
Sbjct: 244  NMLGESTCAAELLVLLEDTDMTDT 267



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERD-SGI 2983
            EG ++HL   +    +    + WYF  K++    +FK   D    TL +  V   D  G 
Sbjct: 848  EGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 903

Query: 2984 YTCKAYNKRGEAFTSS 2999
            Y C+A N  G+  TS+
Sbjct: 904  YVCEALNDSGKTATSA 919



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 4/125 (3%)

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
            TE +  +   + + D+ +  T  ++ + ++A AP   +  +  +V  G + +F C +   
Sbjct: 897  TEDHQGEYVCEALNDSGKTATSAKLTVVKRA-APVIKRKIEPLEVALGHLAKFTCEIQSA 955

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P     WF   R+I +  + K  +  S    +L I    + D G  TC A N+ G  +  
Sbjct: 956  PNVRFQWFKAGREIYE--SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT 1013

Query: 478  CRLNV 482
              L V
Sbjct: 1014 ATLTV 1018



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P   + I+  EV  GH       +     P +R +W+  GR + +  +          +L
Sbjct: 929  PVIKRKIEPLEVALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSSKYISSL 986

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +IL     D G Y CKA+N  G    T+++ V
Sbjct: 987  EILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LDITHTYEEDSGIYTCKAT 2851
            F C ++ +  P ++ +WF   + +    +  S     Y+S L+I  T   D G YTCKA+
Sbjct: 948  FTCEIQSA--PNVRFQWFKAGREIYESDKC-SIRSSKYISSLEILRTQVVDCGEYTCKAS 1004

Query: 2852 NSKGSATTSGSLRCT 2866
            N  GS + + +L  T
Sbjct: 1005 NEYGSVSCTATLTVT 1019



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/90 (26%), Positives = 37/90 (41%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P+  +K++P  V     A+F  E    P    +W++    I  S    I +    S L I
Sbjct: 929  PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 988

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +  V D   +   A N  G+  C+A L V
Sbjct: 989  LRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 56/262 (21%), Positives = 107/262 (40%), Gaps = 18/262 (6%)

Query: 1410 LESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLE 1469
            +ES++    E++ Y    SR K  D    +  +    V+  K  E++   +    E   E
Sbjct: 753  VESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLKPSEEKE-ESSSE 811

Query: 1470 PVTD--SNLKVEWFKNGQPVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVN--- 1523
              T+  + +K++  + G     G     P+ D      DI+ L    + I   + VN   
Sbjct: 812  SGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLT---TSITNAKEVNWYF 868

Query: 1524 ---LVGTDEVSCRLTCRSTTDIVR---STQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
               LV +DE    L  ++T  +V    +T++  G    + L D  K   +  +  V   A
Sbjct: 869  ENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 928

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P+    ++ +E+  G  A F   +   S   ++ +W+   + +    + +  ++    +L
Sbjct: 929  PVIKRKIEPLEVALGHLAKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSL 986

Query: 1638 DIMSCLPEDSGTYTCRAINALG 1659
            +I+     D G YTC+A N  G
Sbjct: 987  EILRTQVVDCGEYTCKASNEYG 1008



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 30/137 (21%), Positives = 59/137 (43%), Gaps = 10/137 (7%)

Query: 1270 IERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVH 1329
            ++ S+   ++ +E   E++  ++        ++ED  ++  P     L +  + EG  VH
Sbjct: 799  LKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTP-----LVDTVSEEGDIVH 853

Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED-SGVYTCQAT 1388
            L   +         V W+   K + +  +F+   + +   L +  V  ED  G Y C+A 
Sbjct: 854  LTTSIT----NAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEAL 909

Query: 1389 NQLGEAVTSCALRVIAK 1405
            N  G+  TS  L V+ +
Sbjct: 910  NDSGKTATSAKLTVVKR 926



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 33/143 (23%), Positives = 61/143 (42%), Gaps = 11/143 (7%)

Query: 3658 EPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDC 3717
            E +  S  +SGTE +  ++  + + E   I+++ P        + D +   EG  VH   
Sbjct: 803  EEKEESSSESGTEEVATVK--IQEAEGGLIKEDGP---MIHTPLVDTVS-EEGDIVHLTT 856

Query: 3718 RVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD-AGEYTCRATNKW 3776
             +    +    ++W+   +   +  +   L D     L ID +   D  GEY C A N  
Sbjct: 857  SITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDS 912

Query: 3777 GSATTTAKITCSAKRDIVLESQL 3799
            G   T+AK+T   +   V++ ++
Sbjct: 913  GKTATSAKLTVVKRAAPVIKRKI 935



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAED-SGVYTVVARNAAGEAQLSASMTV 1135
            V WYF  K + S  + +   D     L I  V  ED  G Y   A N +G+   SA +TV
Sbjct: 864  VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 923

Query: 1136 ETRSS 1140
              R++
Sbjct: 924  VKRAA 928



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/68 (29%), Positives = 34/68 (50%)

Query: 2667 EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            E ++ PN++ +WFK G  +    +        + +L I   +  D G YTCKA+N  G  
Sbjct: 951  EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 1010

Query: 2727 VSTASIKI 2734
              TA++ +
Sbjct: 1011 SCTATLTV 1018



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR-FGYI 694
           PP F+  LK +   +G    FE  +  VG+P   + W K  + +  S  +T I    G  
Sbjct: 166 PPHFLKELKPIRCAQGLPAIFEYTV--VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 223

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           +  +     +DSG Y C+A +  G +   A L V
Sbjct: 224 TFIVNDPQREDSGLYICKAENMLGESTCAAELLV 257



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 17/69 (24%), Positives = 37/69 (53%)

Query: 2936 EPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            E ++ P+++ +W+  G+ + +  +  + S     +L+++     D G YTCKA N+ G  
Sbjct: 951  EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 1010

Query: 2996 FTSSTVYCT 3004
              ++T+  T
Sbjct: 1011 SCTATLTVT 1019



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 6/118 (5%)

Query: 1692 EDTSKYQRHSAQDEVITQ-APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG 1750
            E+ +  +   A+  +I +  P+   P+ D    E    H    +    +    V W    
Sbjct: 815  EEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFEN 870

Query: 1751 VPIEASNRLTTMHDFGYVALNMKYVNPED-SGTYTCRAINELGEAVTSSTLFVQSKAS 1807
              + +  +   + D     L +  VN ED  G Y C A+N+ G+  TS+ L V  +A+
Sbjct: 871  KLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 928



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P    PL    + EG  +H  T I    +    + W    + + +  +F  +      +L
Sbjct: 835 PMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQNTYTL 890

Query: 697 DMLSLNIQD-SGEYTCRAVSATGVAETKAVLHVTPRA 732
            +  +N +D  GEY C A++ +G   T A L V  RA
Sbjct: 891 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 927



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 1/116 (0%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF-EARVEPQSDLTMTVEW 1079
            +Y+ +A   S +T    K+T   R    +K   + +E    H  +   E QS   +  +W
Sbjct: 903  EYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQW 962

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +  G++I  +++          +L+I   +  D G YT  A N  G    +A++TV
Sbjct: 963  FKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA-MNFGWVYPEDSGEYLCRA 4050
            KF C++     PN++ +WF  G+ +   ++ + I    Y++ +        D GEY C+A
Sbjct: 947  KFTCEIQSA--PNVRFQWFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEYTCKA 1003

Query: 4051 TNLYGMDETKAVIKTT 4066
            +N YG     A +  T
Sbjct: 1004 SNEYGSVSCTATLTVT 1019



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDI-LYCYEENSGEYECVATNKLGRDSTKANL 3372
            +V W++  K +P   +++   D     L I     E++ GEY C A N  G+ +T A L
Sbjct: 863  EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 921



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 6/82 (7%)

Query: 1459 GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDLIAEDSGIY 1517
            G    F C+++     N++ +WFK G+ +    +   I    Y++ L+I+     D G Y
Sbjct: 943  GHLAKFTCEIQSAP--NVRFQWFKAGREIYESDKCS-IRSSKYISSLEILRTQVVDCGEY 999

Query: 1518 TCRAVNLVGTDEVSCRLTCRST 1539
            TC+A N  G+  VSC  T   T
Sbjct: 1000 TCKASNEYGS--VSCTATLTVT 1019



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 3575 AHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
            A F C +   +  ++R +WF  G+ +    +    +      LEI      D G YTCKA
Sbjct: 946  AKFTCEI--QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 1003

Query: 3635 TNRHGEATVSCKLQV 3649
            +N +G  + +  L V
Sbjct: 1004 SNEYGSVSCTATLTV 1018



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V R  PV  + ++ ++ +  G  A F C +     P ++ +WF+  + I +S + +    
Sbjct: 924  VKRAAPVIKRKIEPLE-VALGHLAKFTCEIQSA--PNVRFQWFKAGREIYESDKCSIRSS 980

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                S+ I   +  D G Y C+ASN  G
Sbjct: 981  KYISSLEILRTQVVDCGEYTCKASNEYG 1008



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 5/93 (5%)

Query: 1573 VTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF 1632
            +    P+  T L +   +EG   H    +    +    V WY  NK + S  +F    + 
Sbjct: 830  IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQDQ 885

Query: 1633 GFVALDIMSCLPED-SGTYTCRAINALGEAVTS 1664
                L I     ED  G Y C A+N  G+  TS
Sbjct: 886  NTYTLVIDKVNTEDHQGEYVCEALNDSGKTATS 918



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 6/103 (5%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I +  P+   PL +     EG  +HL   +    +    V W+   + V    +FK   D
Sbjct: 830  IKEDGPMIHTPLVDTVS-EEGDIVHLTTSITNAKE----VNWYFENKLVPSDEKFKCLQD 884

Query: 1232 FGFVALDIIHATSAD-TGEYTVRAVNHLGSAHTSAIVRVIERS 1273
                 L I    + D  GEY   A+N  G   TSA + V++R+
Sbjct: 885  QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA 927



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/64 (29%), Positives = 31/64 (48%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P+++ +WF  G+++    +        I  L+IL     + GEY C A+N+ G  S  A 
Sbjct: 956  PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTAT 1015

Query: 3372 LKCT 3375
            L  T
Sbjct: 1016 LTVT 1019


>BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein C,
            fast type protein.
          Length = 1141

 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 106/431 (24%), Positives = 181/431 (41%), Gaps = 56/431 (12%)

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPC-RVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD 4456
            +R+ +  V+  K   FTKK+ P  +V    + +  VE     L L KW++    IK S  
Sbjct: 243  KRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTL-KWFKNGQEIKPSSK 301

Query: 4457 FQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
            +       K IL I +  + D A +    ++     KC   L V+E          PP  
Sbjct: 302  YVFENVGKKRILTINKCTLADDAAYEVAVKDE----KCFTELFVKE----------PPVL 347

Query: 4517 TLTA-QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI---LEEDGTYTLL 4572
             +T  ++  V  G  V +  +V+  +   V W+K+G ++  +   K     ++DG   +L
Sbjct: 348  IVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406

Query: 4573 IL-EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
            I  +   +D G+Y+   I + G+  C+AE +V     ++K            E+++ + D
Sbjct: 407  IFSDVVQEDRGRYQ--VITNGGQ--CEAELIV-----EEKQL----------EVLQDIAD 447

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V   +   F C++  + + T +WYK    ++PSK   +S     + L I +  PEDEG
Sbjct: 448  LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQ------PDQAD-----NLPALTPLRDIVVYEGQPAQF 4740
            DY  V    A  ++++AKL   +      P Q       +    T    IVV  G   + 
Sbjct: 507  DYTFVPDGYA--LSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRL 564

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEG-NNAVLLIGNTYEEDTGTFTCRATTAA 4799
               IT +  P   WL+   +   T     I +  + +  +I +   ED G +T + T   
Sbjct: 565  DVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPV 624

Query: 4800 GQVETSAKLVV 4810
            G+   S  L V
Sbjct: 625  GEDVASIFLQV 635



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 145/652 (22%), Positives = 245/652 (37%), Gaps = 63/652 (9%)

Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHP---KPRVMWLLNGNTIVNGSRYKLTYDGMYHFD 4168
            VF+  PD+V+VE G+ A    +V G     KP + W   G  +  GS+        + F 
Sbjct: 53   VFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWF-KGKWLELGSKS----GARFSFK 107

Query: 4169 IPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHD-DYRGVLKNAPRPWYDETTQYQRT 4227
                   +   +E+              L+V  +   D  G   +   P  D + Q   +
Sbjct: 108  ESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLES 167

Query: 4228 ETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQEL-EN 4286
                ++T E++      G +D    LK + + E E +     K+KK+++      E+ E 
Sbjct: 168  ---FKRTSEKKS--DTAGELDFSGLLKKREVVEEEKK-----KKKKDDDDLGIPPEIWEL 217

Query: 4287 EQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQ-----RYEDNLDQTEEVTEQRVQKKV 4341
             +  K+S   +   QY I   +     + K+  +      +   LD   +V       K+
Sbjct: 218  LKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGN---KI 274

Query: 4342 TQKPRIPDPSESTVHGKEVHVAKQKQTQK-EVVGDKEIT--RKITSTETTEIEHKAQTQE 4398
                 I DP  +    K     K       E VG K I    K T  +    E   + ++
Sbjct: 275  KLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEK 334

Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ 4458
               E  VK   P +    ++  +VF  ++    VE   E   ++ W ++   +     F+
Sbjct: 335  CFTELFVK-EPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM-WMKDGVELTREDSFK 392

Query: 4459 I-HTFST---KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP 4514
              + F     + ILI   V  ED   +  +    GG  +C A L+VEEK+ +    I   
Sbjct: 393  ARYRFKKDGKRHILIFSDVVQEDRGRYQVITN--GG--QCEAELIVEEKQLEVLQDIA-- 446

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLIL 4574
              T+ A    V   ++   D KVTG       W KNG +V+P  R  I      + L+I 
Sbjct: 447  DLTVKASEQAVFKCEVS--DEKVTGK------WYKNGVEVRPSKRITISHVGRFHKLVID 498

Query: 4575 EAYPQDSGKYECV----AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            +  P+D G Y  V    A++ + +     E  V     ++ PK     +    E      
Sbjct: 499  DVRPEDEGDYTFVPDGYALSLSAKLNF-LEIKVEYVPKQEPPKIHLDCSGKTSE-----N 552

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK-YFQMSRTADEYTLRISEAFPED 4689
              +V  G  +     I G+P P   W KGD++   ++   ++ +  D  +  I  A  ED
Sbjct: 553  AIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRED 612

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADNLPALTPLRDIVVYEGQPAQF 4740
            EG Y     N  G    +  L+V   PD  + +   +   D  +   +P  +
Sbjct: 613  EGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMY 664



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 68/295 (23%), Positives = 111/295 (37%), Gaps = 15/295 (5%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            EQ    V F G+P P + W +   P+  S    + T    ++  +RQ    DS  +    
Sbjct: 856  EQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-VHVRTSDFDTVFFVRQAARSDSGEYELSV 914

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
            +        +  + V EK          P   +  + V  T+  +     K  G   I  
Sbjct: 915  QIENMKDTATIRIRVVEK--------AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 966

Query: 4546 YWL-KNGKKVQP--DIRNKILEEDGTYTLLIL--EAYPQDSGKYECVAINSAGEARCDAE 4600
            Y++ K  KK     ++  +      T + LI+  E Y +   +  C   +S G ++  A 
Sbjct: 967  YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             ++    T    + +       P+ + PL D++V  G +   +C + G P P V W K  
Sbjct: 1027 -ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNK 1085

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
              I+    F ++      TL I    P D G Y C A N  G      KL+V  P
Sbjct: 1086 MEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1140



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 34/94 (36%), Positives = 51/94 (54%), Gaps = 2/94 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F  P+ D  V    +A     +   G PK +V W++N + I    +    +  G + 
Sbjct: 1047 APKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            LN++  +P D+GTYTCRA+NELGEA+    L V+
Sbjct: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 1/93 (1%)

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
            +AP+F+    DR V  G     +C V G P P+V W  N  +IR+D    ++ N  G   
Sbjct: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF-LITNYQGVLT 1104

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            L I   +  D+G  TC A N+ GE   +C+L V
Sbjct: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 30/95 (31%), Positives = 51/95 (53%), Gaps = 3/95 (3%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP+F+T L     ++ G SA   C +  +P P  +V W  N   ++   ++  +N  G  
Sbjct: 1047 APKFLTPLIDRVVVA-GYSAALNCAVRGHPKP--KVVWMKNKMEIREDPKFLITNYQGVL 1103

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             L+I      D+G YTC+A+N LG+A++  +L V+
Sbjct: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 5/106 (4%)

Query: 2098 KPIEEEQPGQR--PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            KP E ++   R  P FLT L     +  G  A   C V     P   + W  N  +IR  
Sbjct: 1035 KPFEYKEHDFRMAPKFLTPLID-RVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIRED 1091

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             ++  T+  G + L+I      D+GTY C+A N+LGEA+  C L+V
Sbjct: 1092 PKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 24/53 (45%), Positives = 32/53 (60%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAV 1662
            KV W  N   ++   +F  TN  G + L+I    P D+GTYTCRA+N LGEA+
Sbjct: 1078 KVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1130



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/90 (32%), Positives = 39/90 (43%)

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            +APKF+       V  G    LN    G P P++ W K+ + I  +P+  I    G  TL
Sbjct: 1046 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +I R    DA  Y C A N  G      +L
Sbjct: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKL 1135



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+F   L +   V G +  L C ++  G    +V W  N   I+   +F        + 
Sbjct: 1047 APKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L++    P D+G YTC+A N+LGEA+  C L V
Sbjct: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/88 (32%), Positives = 38/88 (43%)

Query: 4724 LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNT 4783
            LTPL D VV  G  A     +    KP + W++    I E P F + +      L I   
Sbjct: 1051 LTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRP 1110

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               D GT+TCRA    G+     KL V+
Sbjct: 1111 SPFDAGTYTCRAVNELGEALAECKLEVR 1138



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 36/107 (33%), Positives = 50/107 (46%), Gaps = 5/107 (4%)

Query: 2354 RELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQ-EGQTAHFDCRLIPVGDPTLKVEW 2412
            R L++   FK  E  E   R  P F  PL  ID +   G +A  +C +   G P  KV W
Sbjct: 1026 RILKTGITFKPFEYKEHDFRMAPKFLTPL--IDRVVVAGYSAALNCAVR--GHPKPKVVW 1081

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             +N+  I +  +   T+  G +++ I      D G Y CRA N LGE
Sbjct: 1082 MKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1128



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 5/106 (4%)

Query: 2630 PEMFVDTGVQQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
            P  + +   + AP F T L   D++V  G    L   V  R  P  K+ W KN + +   
Sbjct: 1036 PFEYKEHDFRMAPKFLTPL--IDRVVVAGYSAALNCAV--RGHPKPKVVWMKNKMEIRED 1091

Query: 2689 ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +   T   G++TL+I      D+G YTC+A N LGEA++   +++
Sbjct: 1092 PKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+F T   D ++    SA   C +        +V W  N   +    +    N  G + L
Sbjct: 1048 PKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             I      DAG YTC+A N  GEA   CKL+V+
Sbjct: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 2/77 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G +A     +RG+P P V W + K  + E  K+ +  N Q G ++L I++  P D G YT
Sbjct: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQ-GVLTLNIRRPSPFDAGTYT 1119

Query: 146  CTARNQYGEAICSVYIQ 162
            C A N+ GEA+    ++
Sbjct: 1120 CRAVNELGEALAECKLE 1136



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+F+ PL     + G        +   G P  K+ W+KN   I    +F      G ++L
Sbjct: 1048 PKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++   +  D+G YTCRAV+  G A  +  L V
Sbjct: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 763  EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822
            E      P+F+ PL D   +  G +A     +     P  +V W K+   I    +    
Sbjct: 1041 EHDFRMAPKFLTPLIDR-VVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLIT 1097

Query: 823  FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               G ++LNI      DAG+YT RAVN+LGEA++   + V
Sbjct: 1098 NYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 6/84 (7%)

Query: 265 PPKIAQKPRNSKL----QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
           PPKI + PR+ +     + G      V   G PRP+V W K G  L  S  H + T+   
Sbjct: 837 PPKI-RLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH-VRTSDFD 894

Query: 321 TTLRVRNTQKSDSGHYTLLAENPN 344
           T   VR   +SDSG Y L  +  N
Sbjct: 895 TVFFVRQAARSDSGEYELSVQIEN 918



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PKF+T +    V         C V  +  PK ++ W +N   +    ++      G ++L
Sbjct: 1048 PKFLTPLIDRVVVAGYSAALNCAV--RGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            +I      D+G Y CRAVN+ GE   +  +  +
Sbjct: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F  P+ +  V  G+   L   +     P  +V W  N   +++  +F  T   G + L
Sbjct: 1048 PKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1105

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +I      D GTY C+A N +GEA+    ++V
Sbjct: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+F TP+ D++ +  G  A     +   G    +V W+K+   +    +       G + 
Sbjct: 1048 PKFLTPLIDRVVVA-GYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I+  +  DAG YTCRA N +G+A     L +
Sbjct: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 4103 EESKARCPPVFVS-LPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT- 4160
            +E   R  P F++ L D V V  G  A   C V GHPKP+V+W+ N   I    ++ +T 
Sbjct: 1040 KEHDFRMAPKFLTPLIDRVVVA-GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITN 1098

Query: 4161 YDGMYHFDIPKTRQYDTG 4178
            Y G+   +I +   +D G
Sbjct: 1099 YQGVLTLNIRRPSPFDAG 1116



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 3/98 (3%)

Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223
            +P    E   +  P F+ PL +   V+ G +  L C +   G P  +V W  N   +   
Sbjct: 1035 KPFEYKEHDFRMAPKFLTPLIDRVVVA-GYSAALNCAVR--GHPKPKVVWMKNKMEIRED 1091

Query: 1224 SRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261
             +F      G + L+I   +  D G YT RAVN LG A
Sbjct: 1092 PKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1129



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 3/66 (4%)

Query: 1719 DIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPE 1778
            D+ V  ++ A F+     V D K+  +W +NGV +  S R+T  H   +  L +  V PE
Sbjct: 447  DLTVKASEQAVFKCE---VSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPE 503

Query: 1779 DSGTYT 1784
            D G YT
Sbjct: 504  DEGDYT 509



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 3/108 (2%)

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTI 1489
            +K  +  +    + P+F+T P     V+ G      C +        KV W KN   +  
Sbjct: 1034 FKPFEYKEHDFRMAPKFLT-PLIDRVVVAGYSAALNCAVRG--HPKPKVVWMKNKMEIRE 1090

Query: 1490 GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
              +F   +  G + L+I      D+G YTCRAVN +G     C+L  R
Sbjct: 1091 DPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/79 (30%), Positives = 32/79 (40%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
            G  A     + G+P+P+V W KN   +    K  I       TL +R     D+G YT  
Sbjct: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1121

Query: 340  AENPNGCIVTSGYLAVESP 358
            A N  G  +    L V  P
Sbjct: 1122 AVNELGEALAECKLEVRVP 1140



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 7/114 (6%)

Query: 3028 LEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASL--IPTGDQSMVIEWF 3085
            L+  +  +P +  + D    P+F T   D V      +A Y A+L     G     + W 
Sbjct: 1028 LKTGITFKPFEYKEHDFRMAPKFLTPLIDRV-----VVAGYSAALNCAVRGHPKPKVVWM 1082

Query: 3086 YNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
             N   I    +       G++ L I      D+GTY+CRA N+ G+A    KLE
Sbjct: 1083 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLE 1136



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 3/91 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+F   + D + V  G     +C V   G P  ++ W  N        +    N  G + 
Sbjct: 1048 PKFLTPLIDRV-VVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L+I      DAG YTCRA N+ G A    K+
Sbjct: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 3/85 (3%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P+++ P+  +  +V G    L   V  +  P  K+ W  N   + +  +F +T+  G +T
Sbjct: 1048 PKFLTPLI-DRVVVAGYSAALNCAV--RGHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEA 2995
            L++      D+G YTC+A N+ GEA
Sbjct: 1105 LNIRRPSPFDAGTYTCRAVNELGEA 1129



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P+F+T L     V  G +A   C V     P  ++ +  N   ++   +F IT   G ++
Sbjct: 1048 PKFLTPLIDRV-VVAGYSAALNCAVRG--HPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1104

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
            L+I+   P DAG Y+ +A+N LG   +   + V
Sbjct: 1105 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 19/55 (34%), Positives = 29/55 (52%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W  N +E++   +F  T+  G +TL+I      DAG Y C+A+N  G
Sbjct: 1073 GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/64 (32%), Positives = 30/64 (46%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P  KV W  N   ++   +F      G + L I    P D+G Y CRA N  GEA+    
Sbjct: 1075 PKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECK 1134

Query: 3510 MKVQ 3513
            ++V+
Sbjct: 1135 LEVR 1138



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 2/69 (2%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G SA   C V     P  K+ W  N   +R   +    +  G + L+I      D+G Y 
Sbjct: 1062 GYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYT 1119

Query: 3224 CRAYNKYGE 3232
            CRA N+ GE
Sbjct: 1120 CRAVNELGE 1128



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G   + +  + G P PV +W  K   +    +   R  ++    S +I+     DEG YT
Sbjct: 559 GNKLRLDVSITGEPPPVATWL-KGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 617

Query: 146 CTARNQYGEAICSVYIQ 162
               N  GE + S+++Q
Sbjct: 618 IKVTNPVGEDVASIFLQ 634



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 8/99 (8%)

Query: 751 EDYSKYQ---HQESIEEQTSQRPQFIRPLQDLGEL--QEGRNAHFEAQLTPVSDPTMRVE 805
           ED  +YQ   +    E +     + +  LQD+ +L  +    A F+ +   VSD  +  +
Sbjct: 414 EDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCE---VSDEKVTGK 470

Query: 806 WYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
           WYK+G  +  S RIT      +  L I  +R ED G YT
Sbjct: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/49 (40%), Positives = 26/49 (53%)

Query: 1071 SDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVV 1119
            SD  +T +WY NG ++  + RI   H   +  L I  VR ED G YT V
Sbjct: 463  SDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH-NHTTLRVRNTQKSDSGHYTL 338
           G   +  V ++G P P  TW K  +    +     I    + ++  + + Q+ D G YT+
Sbjct: 559 GNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 618

Query: 339 LAENPNGCIVTSGYLAV 355
              NP G  V S +L V
Sbjct: 619 KVTNPVGEDVASIFLQV 635



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            ++  + A F C    V D  +  +W++N   +  S RIT +H   +  + I  VR EDEG
Sbjct: 450  VKASEQAVFKCE---VSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506

Query: 2448 VY 2449
             Y
Sbjct: 507  DY 508



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 3/88 (3%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D +  P+F+T +  +  +V   +    C +   G P  KV W  N   +    +F     
Sbjct: 1043 DFRMAPKFLTPLIDRV-VVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNY 1099

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             G + +N     P D+G Y CRA N  G
Sbjct: 1100 QGVLTLNIRRPSPFDAGTYTCRAVNELG 1127



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++ L + V   G +    C V     P  K+ W  N   +    ++  T+    ++L+I
Sbjct: 1050 FLTPLIDRVVVAGYSAALNCAVRGHPKP--KVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107

Query: 2836 THTYEEDSGIYTCKATNSKGSA 2857
                  D+G YTC+A N  G A
Sbjct: 1108 RRPSPFDAGTYTCRAVNELGEA 1129


>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein LIG-1
            protein.
          Length = 1094

 Score = 91.5 bits (217), Expect = 7e-17
 Identities = 72/270 (26%), Positives = 115/270 (42%), Gaps = 36/270 (13%)

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR-GGTAKCSANLVVEEKRR 4505
            ENF   ++ D ++  ++T  IL +RQV       +  V  N  G T    A L V     
Sbjct: 543  ENFVHVHAQDGEVMEYTT--ILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN---- 596

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK---I 4562
                  V PSFT T  ++ + +  + RL+   TG     + W K+G    P  R +   +
Sbjct: 597  ------VLPSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHV 650

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
            + +D  +   I +    D+G Y C A NSAG    +A                T      
Sbjct: 651  MPDDDVF--FITDVKIDDAGVYSCTAQNSAGSISANA----------------TLTVLET 692

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P ++ PL+D++V+ G+ +   CK  G P P + W+KGD+ +  ++   +  T D   L +
Sbjct: 693  PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHL--TPDNQLLVV 750

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 ED G Y C   N+ G     ++L V
Sbjct: 751  QNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 85.0 bits (201), Expect = 6e-15
 Identities = 54/187 (28%), Positives = 79/187 (42%), Gaps = 7/187 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F K   D  +    M R +C  TG P P++ W  +          + +     +    
Sbjct: 599 PSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFF 658

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           IT+V + D+GV +C A+N +G  +    L V+E   +V P   +R     V  GE V L 
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVP-LEDRV----VSVGETVALQ 713

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +A G P PRITW K   P+  +   R H       L +    A DA  Y C   N  G+
Sbjct: 714 CKATGNPPPRITWFKGDRPL--SLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGT 771

Query: 572 TATRARL 578
               ++L
Sbjct: 772 ERAHSQL 778



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 51/200 (25%), Positives = 87/200 (43%), Gaps = 18/200 (9%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE---NFPIKNSPDFQIHTFSTKSI 4467
            P FTK      +     AR E    G P P I W ++   +FP     + ++H      +
Sbjct: 599  PSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAAR--ERRMHVMPDDDV 656

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
              I  V ++D+ V++  A+N  G+   +A L V E           PS  +  ++  V+ 
Sbjct: 657  FFITDVKIDDAGVYSCTAQNSAGSISANATLTVLE----------TPSLVVPLEDRVVSV 706

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+ V L  K TG  P  + W K  + +    R+ +  ++    L++     +D+G+Y C 
Sbjct: 707  GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDN--QLLVVQNVVAEDAGRYTCE 764

Query: 4588 AINSAGEARCDAECVVSLPA 4607
              N+ G  R  ++  V LPA
Sbjct: 765  MSNTLGTERAHSQLSV-LPA 783



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 47/192 (24%), Positives = 75/192 (39%), Gaps = 8/192 (4%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEY 4678
            N  P   +   D  +         C   G P P + W K G      ++  +M    D+ 
Sbjct: 596  NVLPSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDD 655

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
               I++   +D G Y C A NSAG ++  A L V +         + PL D VV  G+  
Sbjct: 656  VFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPS-----LVVPLEDRVVSVGETV 710

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              + + T    P I W +    +  T    +  +  N +L++ N   ED G +TC  +  
Sbjct: 711  ALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD--NQLLVVQNVVAEDAGRYTCEMSNT 768

Query: 4799 AGQVETSAKLVV 4810
             G     ++L V
Sbjct: 769  LGTERAHSQLSV 780



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 58/205 (28%), Positives = 79/205 (38%), Gaps = 16/205 (7%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-FINDRQI--RDDYNHKIL 441
           + +  L PQ +   +      GK  RF C         +T+ +  D ++    D  + + 
Sbjct: 488 VCDDFLKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVH 547

Query: 442 VNESGNHALMITN------VTLSDSGVVTCVARNKSGET-AFQCRLNVIEKEQVVAPKFV 494
           V+      +  T       VT    G   CV  N  G T + + RL V      V P F 
Sbjct: 548 VHAQDGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN-----VLPSFT 602

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGGASTLDIPRA 553
           +    + +R      L   A G P P+I WQKDG    P   E R+H         I   
Sbjct: 603 KTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDV 662

Query: 554 KASDAAWYQCTAQNVAGSTATRARL 578
           K  DA  Y CTAQN AGS +  A L
Sbjct: 663 KIDDAGVYSCTAQNSAGSISANATL 687



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  V   +DR V+ G+     C+ TG P P +TWF  DR +     H +  +   N  L+
Sbjct: 693 PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD---NQLLV 749

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
           + NV   D+G  TC   N  G      +L+V+
Sbjct: 750 VQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   V ++D + V  G  V   C+    G+P  RI WF   RP +   R H   D   + 
Sbjct: 693  PSLVVPLEDRV-VSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLV 749

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
              +  + A DAG YTC  +N  G+    ++++
Sbjct: 750  --VQNVVAEDAGRYTCEMSNTLGTERAHSQLS 779



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
           S   + +L  +  P +     +  +  G     Q + +GNP PR+TWFK  + L  + +H
Sbjct: 680 SISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERH 739

Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            +  T ++  L V+N    D+G YT    N  G
Sbjct: 740 HL--TPDNQLLVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 45/200 (22%), Positives = 77/200 (38%), Gaps = 14/200 (7%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF-GMV 3106
            P FT    DI  I    +A  E +   TG  +  I W  +G T   + R R ++      
Sbjct: 599  PSFTKTPHDIT-IRTTTMARLECAA--TGHPNPQIAWQKDGGTDFPAARERRMHVMPDDD 655

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            V  I   K  D+G YSC A N  G    +  L  +     + P     +++   +  G++
Sbjct: 656  VFFITDVKIDDAGVYSCTAQNSAGSISANATLTVL-----ETPSLVVPLED-RVVSVGET 709

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               +C      +P  +I W+   +P+  + R     D   +V+     +  D+G Y C  
Sbjct: 710  VALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAE--DAGRYTCEM 765

Query: 3227 YNKYGEDFTRATINCYGKGG 3246
             N  G +   + ++     G
Sbjct: 766  SNTLGTERAHSQLSVLPAAG 785



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P    P+++  V+ G  V L+   T   +P  R+ W+   RP+    R   T D  
Sbjct: 689  VLETPSLVVPLEDRVVSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTERHHLTPD-- 744

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD 2078
               L +    AED G Y C+ +N +G     S + V   +G   D
Sbjct: 745  NQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAAGCRKD 789



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV++ P     L +     G  V L+C+    G+   R+ WF   +P+    R      
Sbjct: 687  LTVLETPSLVVPLEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTP- 743

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             D   L + +V  ED+G YTC+ +N LG       L V+
Sbjct: 744  -DNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 4/77 (5%)

Query: 1459 GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYT 1518
            G+ V  +CK     +   ++ WFK  +P+++  R     D   + +   +++AED+G YT
Sbjct: 707  GETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQ--NVVAEDAGRYT 762

Query: 1519 CRAVNLVGTDEVSCRLT 1535
            C   N +GT+    +L+
Sbjct: 763  CEMSNTLGTERAHSQLS 779



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            + V + P  +  L     +S G++   +C+    P P  R+ W+   + L    R+  + 
Sbjct: 687  LTVLETPSLVVPLEDRV-VSVGETVALQCKATGNPPP--RITWFKGDRPLSLTERHHLTP 743

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            D     L +  V  ED+G YTC+  N LG   +  +L+V
Sbjct: 744  DNQL--LVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 15/40 (37%), Positives = 20/40 (50%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT 4150
            P F   P  +T+     AR  C  TGHP P++ W  +G T
Sbjct: 599  PSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGT 638



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L + V   G+ +  +C    + +P  +I WF  ++PL    R+  T D     L + +  
Sbjct: 699  LEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVV 754

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
             ED+G YTC+ +N+ G+      L
Sbjct: 755  AEDAGRYTCEMSNTLGTERAHSQL 778



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/96 (22%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P    P++D++ +  G     + +    G+   R+ W K  RP+  + R         
Sbjct: 691  ETPSLVVPLEDRV-VSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTER--HHLTPDN 745

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
              L +++V   DAG YTC   N +G     + L+++
Sbjct: 746  QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 3/107 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV   P F++  H+I     T   LEC     G    ++ W  +G       R R  + 
Sbjct: 593  LTVNVLPSFTKTPHDITIRTTTMARLECAA--TGHPNPQIAWQKDGGTDFPAARERRMHV 650

Query: 1365 F-DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
              D     +  V  +D+GVY+C A N  G    +  L V+    L++
Sbjct: 651  MPDDDVFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVV 697



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P   +P++D  V+  +    + +    G+P  R+ W +   P+  + R     D  
Sbjct: 689  VLETPSLVVPLEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPD-- 744

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
               L ++ V  ED+G YTC   N LG     S L V
Sbjct: 745  NQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 4/91 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  +  ++   V   E V  +C+      P  RI W++  + L    R+    D     L
Sbjct: 693  PSLVVPLEDRVVSVGETVALQCKATGNPPP--RITWFKGDRPLSLTERHHLTPDNQL--L 748

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
             +  V AED+G Y C   N  G +   + +S
Sbjct: 749  VVQNVVAEDAGRYTCEMSNTLGTERAHSQLS 779



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 5/85 (5%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            + P    PL++   +  G+T    C+    G+P  ++ WF+ ++ +  + R   T D   
Sbjct: 691  ETPSLVVPLED-RVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQL 747

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
              + + +V  ED G Y C  SN LG
Sbjct: 748  --LVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P  V PL +   VS G+ + L+C+    G+P  R+ WF   R +++  R     D   + 
Sbjct: 693  PSLVVPLEDRV-VSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTERHHLTPDNQLLV 749

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
            +   +  + D G YT    N LG+    + + V+
Sbjct: 750  VQ--NVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 7/101 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG---VPIEASNRLTTMHDFGY 1767
            P FT    DI +     A  E      G P  ++ W ++G    P     R+  M D   
Sbjct: 599  PSFTKTPHDITIRTTTMARLECAA--TGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV 656

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
              +    V  +D+G Y+C A N  G    ++TL V    SL
Sbjct: 657  FFITD--VKIDDAGVYSCTAQNSAGSISANATLTVLETPSL 695



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 7/99 (7%)

Query: 768 QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827
           + P  + PL+D   +  G     + + T   +P  R+ W+K  RP++ + R         
Sbjct: 691 ETPSLVVPLEDR-VVSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTER--HHLTPDN 745

Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLG--EAISTASIRVAA 864
             L + ++ AEDAG YT    N LG   A S  S+  AA
Sbjct: 746 QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAA 784



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P FT TP D+ +   + A  EC        + ++ W  +G      +R + ++      +
Sbjct: 599  PSFTKTPHDITIRTTTMARLEC--AATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV 656

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              I  V   DAG+Y+C A N  G  + +  L V
Sbjct: 657  FFITDVKIDDAGVYSCTAQNSAGSISANATLTV 689



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 4/92 (4%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P       D ++S   +   +C+     +   R+ WF   +PL    R     D   +++
Sbjct: 693  PSLVVPLEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVV 750

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   V   DAG YTC+ +N  G      +L V
Sbjct: 751  Q--NVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/53 (35%), Positives = 25/53 (47%), Gaps = 1/53 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P + V L D V V  GE     C+ TG+P PR+ W      +    R+ LT D
Sbjct: 693  PSLVVPLEDRV-VSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD 744



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 5/86 (5%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            +  P  V  L     V  G+T   +C+     +P  RI ++   + L    R H+T D  
Sbjct: 690  LETPSLVVPLEDRV-VSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQ 746

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALG 2324
               L +Q+ V EDAG Y+ +  N LG
Sbjct: 747  L--LVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 10/104 (9%)

Query: 909  PEF-KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGR---PVEASSRITTFFNF 964
            P F KTP    I+I+    A  E      G    ++ W KDG    P     R+    + 
Sbjct: 599  PSFTKTP--HDITIRTTTMARLECAAT--GHPNPQIAWQKDGGTDFPAARERRMHVMPDD 654

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
                +T   V + DAG Y+C A N+ G  + +A LT++    ++
Sbjct: 655  DVFFIT--DVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLV 696



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G     + K  GNP P ++W +   PL    ++ +  + Q     L+++ +   D G YT
Sbjct: 707 GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL----LVVQNVVAEDAGRYT 762

Query: 146 CTARNQYG 153
           C   N  G
Sbjct: 763 CEMSNTLG 770



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/96 (20%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN-GQRLINSNKHEIITTHNHTTLR 324
           P   + P +  ++    A+ +   +G+P P++ W K+ G     + +  +    +     
Sbjct: 599 PSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFF 658

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESPT 359
           + + +  D+G Y+  A+N  G I  +  L V E+P+
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPS 694


>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat protein
            LRIG1 protein.
          Length = 1093

 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 72/270 (26%), Positives = 115/270 (42%), Gaps = 36/270 (13%)

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR-GGTAKCSANLVVEEKRR 4505
            ENF   ++ D ++  ++T  IL +RQV       +  V  N  G T    A L V     
Sbjct: 543  ENFVHVHAQDGEVMEYTT--ILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN---- 596

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK---I 4562
                  V PSFT T  ++ + +  + RL+   TG     + W K+G    P  R +   +
Sbjct: 597  ------VLPSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHV 650

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
            + +D  +   I +    D+G Y C A NSAG    +A                T      
Sbjct: 651  MPDDDVF--FITDVKIDDAGVYSCTAQNSAGSISANA----------------TLTVLET 692

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P ++ PL+D++V+ G+ +   CK  G P P + W+KGD+ +  ++   +  T D   L +
Sbjct: 693  PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHL--TPDNQLLVV 750

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 ED G Y C   N+ G     ++L V
Sbjct: 751  QNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 53/187 (28%), Positives = 79/187 (42%), Gaps = 7/187 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F K   D  +    + R +C  TG P P++ W  +          + +     +    
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFF 658

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           IT+V + D+GV +C A+N +G  +    L V+E   +V P   +R     V  GE V L 
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVP-LEDRV----VSVGETVALQ 713

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +A G P PRITW K   P+  +   R H       L +    A DA  Y C   N  G+
Sbjct: 714 CKATGNPPPRITWFKGDRPL--SLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGT 771

Query: 572 TATRARL 578
               ++L
Sbjct: 772 ERAHSQL 778



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 51/200 (25%), Positives = 87/200 (43%), Gaps = 18/200 (9%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE---NFPIKNSPDFQIHTFSTKSI 4467
            P FTK      +     AR E    G P P I W ++   +FP     + ++H      +
Sbjct: 599  PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAAR--ERRMHVMPDDDV 656

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
              I  V ++D+ V++  A+N  G+   +A L V E           PS  +  ++  V+ 
Sbjct: 657  FFITDVKIDDAGVYSCTAQNSAGSISANATLTVLE----------TPSLVVPLEDRVVSV 706

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+ V L  K TG  P  + W K  + +    R+ +  ++    L++     +D+G+Y C 
Sbjct: 707  GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDN--QLLVVQNVVAEDAGRYTCE 764

Query: 4588 AINSAGEARCDAECVVSLPA 4607
              N+ G  R  ++  V LPA
Sbjct: 765  MSNTLGTERAHSQLSV-LPA 783



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 47/192 (24%), Positives = 75/192 (39%), Gaps = 8/192 (4%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEY 4678
            N  P   +   D  +         C   G P P + W K G      ++  +M    D+ 
Sbjct: 596  NVLPSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDD 655

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
               I++   +D G Y C A NSAG ++  A L V +         + PL D VV  G+  
Sbjct: 656  VFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPS-----LVVPLEDRVVSVGETV 710

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              + + T    P I W +    +  T    +  +  N +L++ N   ED G +TC  +  
Sbjct: 711  ALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD--NQLLVVQNVVAEDAGRYTCEMSNT 768

Query: 4799 AGQVETSAKLVV 4810
             G     ++L V
Sbjct: 769  LGTERAHSQLSV 780



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 58/205 (28%), Positives = 79/205 (38%), Gaps = 16/205 (7%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-FINDRQI--RDDYNHKIL 441
           + +  L PQ +   +      GK  RF C         +T+ +  D ++    D  + + 
Sbjct: 488 VCDDFLKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVH 547

Query: 442 VNESGNHALMITN------VTLSDSGVVTCVARNKSGET-AFQCRLNVIEKEQVVAPKFV 494
           V+      +  T       VT    G   CV  N  G T + + RL V      V P F 
Sbjct: 548 VHAQDGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN-----VLPSFT 602

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGGASTLDIPRA 553
           +    + +R      L   A G P P+I WQKDG    P   E R+H         I   
Sbjct: 603 KTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDV 662

Query: 554 KASDAAWYQCTAQNVAGSTATRARL 578
           K  DA  Y CTAQN AGS +  A L
Sbjct: 663 KIDDAGVYSCTAQNSAGSISANATL 687



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  V   +DR V+ G+     C+ TG P P +TWF  DR +     H +  +   N  L+
Sbjct: 693 PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD---NQLLV 749

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
           + NV   D+G  TC   N  G      +L+V+
Sbjct: 750 VQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   V ++D + V  G  V   C+    G+P  RI WF   RP +   R H   D   + 
Sbjct: 693  PSLVVPLEDRV-VSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLV 749

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
              +  + A DAG YTC  +N  G+    ++++
Sbjct: 750  --VQNVVAEDAGRYTCEMSNTLGTERAHSQLS 779



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
           S   + +L  +  P +     +  +  G     Q + +GNP PR+TWFK  + L  + +H
Sbjct: 680 SISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERH 739

Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            +  T ++  L V+N    D+G YT    N  G
Sbjct: 740 HL--TPDNQLLVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 45/200 (22%), Positives = 77/200 (38%), Gaps = 14/200 (7%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF-GMV 3106
            P FT    DI  I    +A  E +   TG  +  I W  +G T   + R R ++      
Sbjct: 599  PSFTKTPHDIT-IRTTTVARLECAA--TGHPNPQIAWQKDGGTDFPAARERRMHVMPDDD 655

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            V  I   K  D+G YSC A N  G    +  L  +     + P     +++   +  G++
Sbjct: 656  VFFITDVKIDDAGVYSCTAQNSAGSISANATLTVL-----ETPSLVVPLED-RVVSVGET 709

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               +C      +P  +I W+   +P+  + R     D   +V+     +  D+G Y C  
Sbjct: 710  VALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAE--DAGRYTCEM 765

Query: 3227 YNKYGEDFTRATINCYGKGG 3246
             N  G +   + ++     G
Sbjct: 766  SNTLGTERAHSQLSVLPAAG 785



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P    P+++  V+ G  V L+   T   +P  R+ W+   RP+    R   T D  
Sbjct: 689  VLETPSLVVPLEDRVVSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTERHHLTPD-- 744

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD 2078
               L +    AED G Y C+ +N +G     S + V   +G   D
Sbjct: 745  NQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAAGCRKD 789



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV++ P     L +     G  V L+C+    G+   R+ WF   +P+    R      
Sbjct: 687  LTVLETPSLVVPLEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTP- 743

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             D   L + +V  ED+G YTC+ +N LG       L V+
Sbjct: 744  -DNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 4/77 (5%)

Query: 1459 GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYT 1518
            G+ V  +CK     +   ++ WFK  +P+++  R     D   + +   +++AED+G YT
Sbjct: 707  GETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQ--NVVAEDAGRYT 762

Query: 1519 CRAVNLVGTDEVSCRLT 1535
            C   N +GT+    +L+
Sbjct: 763  CEMSNTLGTERAHSQLS 779



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            + V + P  +  L     +S G++   +C+    P P  R+ W+   + L    R+  + 
Sbjct: 687  LTVLETPSLVVPLEDRV-VSVGETVALQCKATGNPPP--RITWFKGDRPLSLTERHHLTP 743

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            D     L +  V  ED+G YTC+  N LG   +  +L+V
Sbjct: 744  DNQL--LVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L + V   G+ +  +C    + +P  +I WF  ++PL    R+  T D     L + +  
Sbjct: 699  LEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVV 754

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
             ED+G YTC+ +N+ G+      L
Sbjct: 755  AEDAGRYTCEMSNTLGTERAHSQL 778



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/96 (22%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P    P++D++ +  G     + +    G+   R+ W K  RP+  + R         
Sbjct: 691  ETPSLVVPLEDRV-VSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTER--HHLTPDN 745

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
              L +++V   DAG YTC   N +G     + L+++
Sbjct: 746  QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 15/40 (37%), Positives = 20/40 (50%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT 4150
            P F   P  +T+     AR  C  TGHP P++ W  +G T
Sbjct: 599  PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGT 638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P   +P++D  V+  +    + +    G+P  R+ W +   P+  + R     D  
Sbjct: 689  VLETPSLVVPLEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPD-- 744

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
               L ++ V  ED+G YTC   N LG     S L V
Sbjct: 745  NQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 4/91 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  +  ++   V   E V  +C+      P  RI W++  + L    R+    D     L
Sbjct: 693  PSLVVPLEDRVVSVGETVALQCKATGNPPP--RITWFKGDRPLSLTERHHLTPDNQL--L 748

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
             +  V AED+G Y C   N  G +   + +S
Sbjct: 749  VVQNVVAEDAGRYTCEMSNTLGTERAHSQLS 779



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 3/107 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV   P F++  H+I     T   LEC     G    ++ W  +G       R R  + 
Sbjct: 593  LTVNVLPSFTKTPHDITIRTTTVARLECAA--TGHPNPQIAWQKDGGTDFPAARERRMHV 650

Query: 1365 F-DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
              D     +  V  +D+GVY+C A N  G    +  L V+    L++
Sbjct: 651  MPDDDVFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVV 697



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 5/85 (5%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            + P    PL++   +  G+T    C+    G+P  ++ WF+ ++ +  + R   T D   
Sbjct: 691  ETPSLVVPLED-RVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQL 747

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
              + + +V  ED G Y C  SN LG
Sbjct: 748  --LVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P  V PL +   VS G+ + L+C+    G+P  R+ WF   R +++  R     D   + 
Sbjct: 693  PSLVVPLEDRV-VSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTERHHLTPDNQLLV 749

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
            +   +  + D G YT    N LG+    + + V+
Sbjct: 750  VQ--NVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 7/101 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG---VPIEASNRLTTMHDFGY 1767
            P FT    DI +     A  E      G P  ++ W ++G    P     R+  M D   
Sbjct: 599  PSFTKTPHDITIRTTTVARLECAA--TGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV 656

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
              +    V  +D+G Y+C A N  G    ++TL V    SL
Sbjct: 657  FFITD--VKIDDAGVYSCTAQNSAGSISANATLTVLETPSL 695



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 7/99 (7%)

Query: 768 QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827
           + P  + PL+D   +  G     + + T   +P  R+ W+K  RP++ + R         
Sbjct: 691 ETPSLVVPLEDR-VVSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTER--HHLTPDN 745

Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLG--EAISTASIRVAA 864
             L + ++ AEDAG YT    N LG   A S  S+  AA
Sbjct: 746 QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAA 784



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 4/92 (4%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P       D ++S   +   +C+     +   R+ WF   +PL    R     D   +++
Sbjct: 693  PSLVVPLEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVV 750

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   V   DAG YTC+ +N  G      +L V
Sbjct: 751  Q--NVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/53 (35%), Positives = 25/53 (47%), Gaps = 1/53 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P + V L D V V  GE     C+ TG+P PR+ W      +    R+ LT D
Sbjct: 693  PSLVVPLEDRV-VSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD 744



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P FT TP D+ +   + A  EC        + ++ W  +G      +R + ++      +
Sbjct: 599  PSFTKTPHDITIRTTTVARLEC--AATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV 656

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              I  V   DAG+Y+C A N  G  + +  L V
Sbjct: 657  FFITDVKIDDAGVYSCTAQNSAGSISANATLTV 689



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 5/86 (5%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            +  P  V  L     V  G+T   +C+     +P  RI ++   + L    R H+T D  
Sbjct: 690  LETPSLVVPLEDRV-VSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQ 746

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALG 2324
               L +Q+ V EDAG Y+ +  N LG
Sbjct: 747  L--LVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G     + K  GNP P ++W +   PL    ++ +  + Q     L+++ +   D G YT
Sbjct: 707 GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL----LVVQNVVAEDAGRYT 762

Query: 146 CTARNQYG 153
           C   N  G
Sbjct: 763 CEMSNTLG 770



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/96 (20%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN-GQRLINSNKHEIITTHNHTTLR 324
           P   + P +  ++    A+ +   +G+P P++ W K+ G     + +  +    +     
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFF 658

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESPT 359
           + + +  D+G Y+  A+N  G I  +  L V E+P+
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPS 694



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 7/83 (8%)

Query: 931  ARLE--PIGDSTLRVEWLKDGR---PVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCR 985
            ARLE    G    ++ W KDG    P     R+    +     +T   V + DAG Y+C 
Sbjct: 616  ARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFIT--DVKIDDAGVYSCT 673

Query: 986  AYNAIGQATTSANLTIVTKKDII 1008
            A N+ G  + +A LT++    ++
Sbjct: 674  AQNSAGSISANATLTVLETPSLV 696


>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein LRIG1
            protein.
          Length = 1093

 Score = 91.1 bits (216), Expect = 9e-17
 Identities = 72/270 (26%), Positives = 115/270 (42%), Gaps = 36/270 (13%)

Query: 4447 ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR-GGTAKCSANLVVEEKRR 4505
            ENF   ++ D ++  ++T  IL +RQV       +  V  N  G T    A L V     
Sbjct: 543  ENFVHVHAQDGEVMEYTT--ILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN---- 596

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK---I 4562
                  V PSFT T  ++ + +  + RL+   TG     + W K+G    P  R +   +
Sbjct: 597  ------VLPSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHV 650

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
            + +D  +   I +    D+G Y C A NSAG    +A                T      
Sbjct: 651  MPDDDVF--FITDVKIDDAGVYSCTAQNSAGSISANA----------------TLTVLET 692

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P ++ PL+D++V+ G+ +   CK  G P P + W+KGD+ +  ++   +  T D   L +
Sbjct: 693  PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHL--TPDNQLLVV 750

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 ED G Y C   N+ G     ++L V
Sbjct: 751  QNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 83.4 bits (197), Expect = 2e-14
 Identities = 53/187 (28%), Positives = 79/187 (42%), Gaps = 7/187 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F K   D  +    + R +C  TG P P++ W  +          + +     +    
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFF 658

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           IT+V + D+GV +C A+N +G  +    L V+E   +V P   +R     V  GE V L 
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVP-LEDRV----VSVGETVALQ 713

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +A G P PRITW K   P+  +   R H       L +    A DA  Y C   N  G+
Sbjct: 714 CKATGNPPPRITWFKGDRPL--SLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGT 771

Query: 572 TATRARL 578
               ++L
Sbjct: 772 ERAHSQL 778



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 51/200 (25%), Positives = 87/200 (43%), Gaps = 18/200 (9%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE---NFPIKNSPDFQIHTFSTKSI 4467
            P FTK      +     AR E    G P P I W ++   +FP     + ++H      +
Sbjct: 599  PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAAR--ERRMHVMPDDDV 656

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
              I  V ++D+ V++  A+N  G+   +A L V E           PS  +  ++  V+ 
Sbjct: 657  FFITDVKIDDAGVYSCTAQNSAGSISANATLTVLE----------TPSLVVPLEDRVVSV 706

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+ V L  K TG  P  + W K  + +    R+ +  ++    L++     +D+G+Y C 
Sbjct: 707  GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDN--QLLVVQNVVAEDAGRYTCE 764

Query: 4588 AINSAGEARCDAECVVSLPA 4607
              N+ G  R  ++  V LPA
Sbjct: 765  MSNTLGTERAHSQLSV-LPA 783



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 47/192 (24%), Positives = 75/192 (39%), Gaps = 8/192 (4%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEY 4678
            N  P   +   D  +         C   G P P + W K G      ++  +M    D+ 
Sbjct: 596  NVLPSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDD 655

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
               I++   +D G Y C A NSAG ++  A L V +         + PL D VV  G+  
Sbjct: 656  VFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPS-----LVVPLEDRVVSVGETV 710

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              + + T    P I W +    +  T    +  +  N +L++ N   ED G +TC  +  
Sbjct: 711  ALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD--NQLLVVQNVVAEDAGRYTCEMSNT 768

Query: 4799 AGQVETSAKLVV 4810
             G     ++L V
Sbjct: 769  LGTERAHSQLSV 780



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 58/205 (28%), Positives = 79/205 (38%), Gaps = 16/205 (7%)

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW-FINDRQI--RDDYNHKIL 441
           + +  L PQ +   +      GK  RF C         +T+ +  D ++    D  + + 
Sbjct: 488 VCDDFLKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVH 547

Query: 442 VNESGNHALMITN------VTLSDSGVVTCVARNKSGET-AFQCRLNVIEKEQVVAPKFV 494
           V+      +  T       VT    G   CV  N  G T + + RL V      V P F 
Sbjct: 548 VHAQDGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN-----VLPSFT 602

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP-ELRIHTDGGASTLDIPRA 553
           +    + +R      L   A G P P+I WQKDG    P   E R+H         I   
Sbjct: 603 KTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDV 662

Query: 554 KASDAAWYQCTAQNVAGSTATRARL 578
           K  DA  Y CTAQN AGS +  A L
Sbjct: 663 KIDDAGVYSCTAQNSAGSISANATL 687



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  V   +DR V+ G+     C+ TG P P +TWF  DR +     H +  +   N  L+
Sbjct: 693 PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD---NQLLV 749

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
           + NV   D+G  TC   N  G      +L+V+
Sbjct: 750 VQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P   V ++D + V  G  V   C+    G+P  RI WF   RP +   R H   D   + 
Sbjct: 693  PSLVVPLEDRV-VSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLV 749

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
              +  + A DAG YTC  +N  G+    ++++
Sbjct: 750  --VQNVVAEDAGRYTCEMSNTLGTERAHSQLS 779



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
           S   + +L  +  P +     +  +  G     Q + +GNP PR+TWFK  + L  + +H
Sbjct: 680 SISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERH 739

Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
            +  T ++  L V+N    D+G YT    N  G
Sbjct: 740 HL--TPDNQLLVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 45/200 (22%), Positives = 77/200 (38%), Gaps = 14/200 (7%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF-GMV 3106
            P FT    DI  I    +A  E +   TG  +  I W  +G T   + R R ++      
Sbjct: 599  PSFTKTPHDIT-IRTTTVARLECAA--TGHPNPQIAWQKDGGTDFPAARERRMHVMPDDD 655

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            V  I   K  D+G YSC A N  G    +  L  +     + P     +++   +  G++
Sbjct: 656  VFFITDVKIDDAGVYSCTAQNSAGSISANATLTVL-----ETPSLVVPLED-RVVSVGET 709

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               +C      +P  +I W+   +P+  + R     D   +V+     +  D+G Y C  
Sbjct: 710  VALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAE--DAGRYTCEM 765

Query: 3227 YNKYGEDFTRATINCYGKGG 3246
             N  G +   + ++     G
Sbjct: 766  SNTLGTERAHSQLSVLPAAG 785



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+E P    P+++  V+ G  V L+   T   +P  R+ W+   RP+    R   T D  
Sbjct: 689  VLETPSLVVPLEDRVVSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTERHHLTPD-- 744

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD 2078
               L +    AED G Y C+ +N +G     S + V   +G   D
Sbjct: 745  NQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAAGCRKD 789



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV++ P     L +     G  V L+C+    G+   R+ WF   +P+    R      
Sbjct: 687  LTVLETPSLVVPLEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTP- 743

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             D   L + +V  ED+G YTC+ +N LG       L V+
Sbjct: 744  -DNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 4/77 (5%)

Query: 1459 GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYT 1518
            G+ V  +CK     +   ++ WFK  +P+++  R     D   + +   +++AED+G YT
Sbjct: 707  GETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQ--NVVAEDAGRYT 762

Query: 1519 CRAVNLVGTDEVSCRLT 1535
            C   N +GT+    +L+
Sbjct: 763  CEMSNTLGTERAHSQLS 779



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            + V + P  +  L     +S G++   +C+    P P  R+ W+   + L    R+  + 
Sbjct: 687  LTVLETPSLVVPLEDRV-VSVGETVALQCKATGNPPP--RITWFKGDRPLSLTERHHLTP 743

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            D     L +  V  ED+G YTC+  N LG   +  +L+V
Sbjct: 744  DNQL--LVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L + V   G+ +  +C    + +P  +I WF  ++PL    R+  T D     L + +  
Sbjct: 699  LEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVV 754

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
             ED+G YTC+ +N+ G+      L
Sbjct: 755  AEDAGRYTCEMSNTLGTERAHSQL 778



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/96 (22%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P    P++D++ +  G     + +    G+   R+ W K  RP+  + R         
Sbjct: 691  ETPSLVVPLEDRV-VSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTER--HHLTPDN 745

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
              L +++V   DAG YTC   N +G     + L+++
Sbjct: 746  QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 15/40 (37%), Positives = 20/40 (50%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT 4150
            P F   P  +T+     AR  C  TGHP P++ W  +G T
Sbjct: 599  PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGT 638



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P   +P++D  V+  +    + +    G+P  R+ W +   P+  + R     D  
Sbjct: 689  VLETPSLVVPLEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPD-- 744

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
               L ++ V  ED+G YTC   N LG     S L V
Sbjct: 745  NQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 4/91 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  +  ++   V   E V  +C+      P  RI W++  + L    R+    D     L
Sbjct: 693  PSLVVPLEDRVVSVGETVALQCKATGNPPP--RITWFKGDRPLSLTERHHLTPDNQL--L 748

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
             +  V AED+G Y C   N  G +   + +S
Sbjct: 749  VVQNVVAEDAGRYTCEMSNTLGTERAHSQLS 779



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 3/107 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV   P F++  H+I     T   LEC     G    ++ W  +G       R R  + 
Sbjct: 593  LTVNVLPSFTKTPHDITIRTTTVARLECAA--TGHPNPQIAWQKDGGTDFPAARERRMHV 650

Query: 1365 F-DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
              D     +  V  +D+GVY+C A N  G    +  L V+    L++
Sbjct: 651  MPDDDVFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVV 697



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 5/85 (5%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            + P    PL++   +  G+T    C+    G+P  ++ WF+ ++ +  + R   T D   
Sbjct: 691  ETPSLVVPLED-RVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQL 747

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
              + + +V  ED G Y C  SN LG
Sbjct: 748  --LVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P  V PL +   VS G+ + L+C+    G+P  R+ WF   R +++  R     D   + 
Sbjct: 693  PSLVVPLEDRV-VSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTERHHLTPDNQLLV 749

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
            +   +  + D G YT    N LG+    + + V+
Sbjct: 750  VQ--NVVAEDAGRYTCEMSNTLGTERAHSQLSVL 781



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 7/101 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG---VPIEASNRLTTMHDFGY 1767
            P FT    DI +     A  E      G P  ++ W ++G    P     R+  M D   
Sbjct: 599  PSFTKTPHDITIRTTTVARLECAA--TGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV 656

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
              +    V  +D+G Y+C A N  G    ++TL V    SL
Sbjct: 657  FFITD--VKIDDAGVYSCTAQNSAGSISANATLTVLETPSL 695



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 7/99 (7%)

Query: 768 QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827
           + P  + PL+D   +  G     + + T   +P  R+ W+K  RP++ + R         
Sbjct: 691 ETPSLVVPLEDR-VVSVGETVALQCKAT--GNPPPRITWFKGDRPLSLTER--HHLTPDN 745

Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLG--EAISTASIRVAA 864
             L + ++ AEDAG YT    N LG   A S  S+  AA
Sbjct: 746 QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAA 784



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 4/92 (4%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P       D ++S   +   +C+     +   R+ WF   +PL    R     D   +++
Sbjct: 693  PSLVVPLEDRVVSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVV 750

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   V   DAG YTC+ +N  G      +L V
Sbjct: 751  Q--NVVAEDAGRYTCEMSNTLGTERAHSQLSV 780



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 19/53 (35%), Positives = 25/53 (47%), Gaps = 1/53 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P + V L D V V  GE     C+ TG+P PR+ W      +    R+ LT D
Sbjct: 693  PSLVVPLEDRV-VSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD 744



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF-GFVI 3616
            P FT TP D+ +   + A  EC        + ++ W  +G      +R + ++      +
Sbjct: 599  PSFTKTPHDITIRTTTVARLEC--AATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV 656

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              I  V   DAG+Y+C A N  G  + +  L V
Sbjct: 657  FFITDVKIDDAGVYSCTAQNSAGSISANATLTV 689



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 5/86 (5%)

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
            +  P  V  L     V  G+T   +C+     +P  RI ++   + L    R H+T D  
Sbjct: 690  LETPSLVVPLEDRV-VSVGETVALQCKA--TGNPPPRITWFKGDRPLSLTERHHLTPDNQ 746

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALG 2324
               L +Q+ V EDAG Y+ +  N LG
Sbjct: 747  L--LVVQNVVAEDAGRYTCEMSNTLG 770



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G     + K  GNP P ++W +   PL    ++ +  + Q     L+++ +   D G YT
Sbjct: 707 GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL----LVVQNVVAEDAGRYT 762

Query: 146 CTARNQYG 153
           C   N  G
Sbjct: 763 CEMSNTLG 770



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 20/96 (20%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN-GQRLINSNKHEIITTHNHTTLR 324
           P   + P +  ++    A+ +   +G+P P++ W K+ G     + +  +    +     
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFF 658

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESPT 359
           + + +  D+G Y+  A+N  G I  +  L V E+P+
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPS 694



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 7/83 (8%)

Query: 931  ARLE--PIGDSTLRVEWLKDGR---PVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCR 985
            ARLE    G    ++ W KDG    P     R+    +     +T   V + DAG Y+C 
Sbjct: 616  ARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFIT--DVKIDDAGVYSCT 673

Query: 986  AYNAIGQATTSANLTIVTKKDII 1008
            A N+ G  + +A LT++    ++
Sbjct: 674  AQNSAGSISANATLTVLETPSLV 696


>Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion molecule
            L1 protein.
          Length = 1257

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 267  EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 322

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 323  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 372

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 373  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 430

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 431  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 475

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 476  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 526

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 527  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 583

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 584  SDQGNYSCVASTELDVVESRAQLLV 608



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 332 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 389

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 390 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 446

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 447 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 503

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 504 NNVTIMANL 512



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 246  TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 302

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 303  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 346

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 347  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 401

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 402  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 455

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 456  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 512

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 513  KVKDAT 518



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 348  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 406

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 407  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 456

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 457  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 512

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 513  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 556

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 557  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 608



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 50/191 (26%), Positives = 78/191 (40%), Gaps = 15/191 (7%)

Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           AP++ K   +  +V EG+     C       P   +++N + +    + ++ + ++GN  
Sbjct: 135 APKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGN-- 192

Query: 450 LMITNVTLSDS-GVVTCVARNKSGETAFQCR---LNVIEKEQVVAPKFVERFST-----L 500
           L   NV  SD+     C A      T  Q     L V     ++  K    F T     L
Sbjct: 193 LYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHL 252

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D   
Sbjct: 253 VALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEEDDGE 309

Query: 561 YQCTAQNVAGS 571
           Y+C A+N  GS
Sbjct: 310 YRCLAENSLGS 320



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 344 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 400

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 401 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 453

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 454 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 510

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 511 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 570

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 571 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 608



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 256 QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 310

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 311 RCLAENSLGSARHAYYVTVE 330



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 333 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 388

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 389 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 445

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 446 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 498

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 499 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 236  IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 293

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 294  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 331



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 250  SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 304

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 305  EDDGEYRCLAENSLGSA 321



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 440 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 492

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 493 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 546

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 547 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 603

Query: 576 ARL 578
           A+L
Sbjct: 604 AQL 606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 199  LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 255

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 256  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 312

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 313  LAENSLGSARHAYYVTVE 330



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 211  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 267

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 268  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 324

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 325  YYVTVEA 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 327  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 383

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 384  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 433



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 333  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 211  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 271  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 330

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 331  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 387

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 388  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 421



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 251  HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 305

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 306  DDGEYRCLAENSLGSA 321



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 244  FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 298

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 299  LLKVGEEDDGEYRCLAENSLG 319



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 426  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 479

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 480  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 516


>M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 1257

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 267  EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 322

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 323  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 372

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 373  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 430

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 431  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 475

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 476  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 526

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 527  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 583

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 584  SDQGNYSCVASTELDVVESRAQLLV 608



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 332 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 389

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 390 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 446

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 447 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 503

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 504 NNVTIMANL 512



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 246  TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 302

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 303  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 346

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 347  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 401

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 402  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 455

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 456  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 512

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 513  KVKDAT 518



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 348  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 406

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 407  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 456

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 457  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 512

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 513  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 556

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 557  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 608



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 50/191 (26%), Positives = 78/191 (40%), Gaps = 15/191 (7%)

Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           AP++ K   +  +V EG+     C       P   +++N + +    + ++ + ++GN  
Sbjct: 135 APKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGN-- 192

Query: 450 LMITNVTLSDS-GVVTCVARNKSGETAFQCR---LNVIEKEQVVAPKFVERFST-----L 500
           L   NV  SD+     C A      T  Q     L V     ++  K    F T     L
Sbjct: 193 LYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHL 252

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D   
Sbjct: 253 VALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEEDDGE 309

Query: 561 YQCTAQNVAGS 571
           Y+C A+N  GS
Sbjct: 310 YRCLAENSLGS 320



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 344 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 400

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 401 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 453

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 454 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 510

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 511 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 570

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 571 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 608



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 256 QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 310

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 311 RCLAENSLGSARHAYYVTVE 330



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 333 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 388

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 389 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 445

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 446 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 498

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 499 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 236  IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 293

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 294  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 331



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 250  SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 304

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 305  EDDGEYRCLAENSLGSA 321



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 440 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 492

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 493 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 546

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 547 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 603

Query: 576 ARL 578
           A+L
Sbjct: 604 AQL 606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 199  LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 255

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 256  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 312

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 313  LAENSLGSARHAYYVTVE 330



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 211  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 267

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 268  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 324

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 325  YYVTVEA 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 327  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 383

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 384  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 433



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 333  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 211  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 271  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 330

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 331  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 387

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 388  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 421



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 251  HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 305

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 306  DDGEYRCLAENSLGSA 321



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 244  FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 298

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 299  LLKVGEEDDGEYRCLAENSLG 319



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 426  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 479

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 480  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 516


>M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1
            protein.
          Length = 1253

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 267  EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 322

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 323  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 372

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 373  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 430

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 431  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 475

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 476  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 526

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 527  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 583

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 584  SDQGNYSCVASTELDVVESRAQLLV 608



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 332 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 389

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 390 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 446

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 447 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 503

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 504 NNVTIMANL 512



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 246  TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 302

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 303  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 346

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 347  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 401

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 402  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 455

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 456  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 512

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 513  KVKDAT 518



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 348  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 406

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 407  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 456

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 457  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 512

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 513  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 556

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 557  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 608



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 50/191 (26%), Positives = 78/191 (40%), Gaps = 15/191 (7%)

Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           AP++ K   +  +V EG+     C       P   +++N + +    + ++ + ++GN  
Sbjct: 135 APKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGN-- 192

Query: 450 LMITNVTLSDS-GVVTCVARNKSGETAFQCR---LNVIEKEQVVAPKFVERFST-----L 500
           L   NV  SD+     C A      T  Q     L V     ++  K    F T     L
Sbjct: 193 LYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHL 252

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D   
Sbjct: 253 VALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEEDDGE 309

Query: 561 YQCTAQNVAGS 571
           Y+C A+N  GS
Sbjct: 310 YRCLAENSLGS 320



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 344 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 400

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 401 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 453

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 454 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 510

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 511 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 570

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 571 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 608



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 256 QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 310

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 311 RCLAENSLGSARHAYYVTVE 330



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 333 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 388

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 389 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 445

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 446 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 498

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 499 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 236  IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 293

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 294  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 331



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 250  SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 304

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 305  EDDGEYRCLAENSLGSA 321



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 440 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 492

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 493 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 546

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 547 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 603

Query: 576 ARL 578
           A+L
Sbjct: 604 AQL 606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 199  LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 255

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 256  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 312

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 313  LAENSLGSARHAYYVTVE 330



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 211  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 267

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 268  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 324

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 325  YYVTVEA 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 327  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 383

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 384  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 433



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 333  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 211  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 271  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 330

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 331  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 387

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 388  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 421



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 251  HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 305

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 306  DDGEYRCLAENSLGSA 321



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 244  FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 298

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 299  LLKVGEEDDGEYRCLAENSLG 319



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 426  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 479

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 480  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 516


>DQ173642-2|ABC25979.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173641-2|ABC25974.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173640-2|ABC25969.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173639-2|ABC25964.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173638-2|ABC25959.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173637-2|ABC25954.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173636-2|ABC25949.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173635-2|ABC25944.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173634-2|ABC25939.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173633-2|ABC25934.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173632-2|ABC25929.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173631-2|ABC25924.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173630-2|ABC25919.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173629-2|ABC25914.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173628-2|ABC25909.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173627-2|ABC25904.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173626-2|ABC25899.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173625-2|ABC25894.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173624-2|ABC25889.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173623-2|ABC25884.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173622-2|ABC25879.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173621-2|ABC25874.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173620-2|ABC25869.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173619-2|ABC25864.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173618-2|ABC25859.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173617-2|ABC25854.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173616-2|ABC25849.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173615-2|ABC25844.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173614-2|ABC25839.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173613-2|ABC25834.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173612-2|ABC25829.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173611-2|ABC25824.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173610-2|ABC25819.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173609-2|ABC25814.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173608-2|ABC25809.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173607-2|ABC25804.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173606-2|ABC25799.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173605-2|ABC25794.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173604-2|ABC25789.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173603-2|ABC25784.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173602-2|ABC25779.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173601-2|ABC25774.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173600-2|ABC25769.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173599-2|ABC25764.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173598-2|ABC25759.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173597-2|ABC25755.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173596-2|ABC25750.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173595-2|ABC25745.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173594-2|ABC25740.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173593-2|ABC25735.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173592-2|ABC25730.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>DQ173589-1|ABB58724.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 1257

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 267  EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 322

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 323  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 372

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 373  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 430

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 431  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 475

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 476  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 526

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 527  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 583

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 584  SDQGNYSCVASTELDVVESRAQLLV 608



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 332 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 389

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 390 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 446

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 447 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 503

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 504 NNVTIMANL 512



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 246  TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 302

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 303  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 346

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 347  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 401

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 402  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 455

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 456  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 512

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 513  KVKDAT 518



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 348  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 406

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 407  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 456

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 457  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 512

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 513  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 556

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 557  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 608



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 50/191 (26%), Positives = 78/191 (40%), Gaps = 15/191 (7%)

Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           AP++ K   +  +V EG+     C       P   +++N + +    + ++ + ++GN  
Sbjct: 135 APKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGN-- 192

Query: 450 LMITNVTLSDS-GVVTCVARNKSGETAFQCR---LNVIEKEQVVAPKFVERFST-----L 500
           L   NV  SD+     C A      T  Q     L V     ++  K    F T     L
Sbjct: 193 LYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHL 252

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D   
Sbjct: 253 VALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEEDDGE 309

Query: 561 YQCTAQNVAGS 571
           Y+C A+N  GS
Sbjct: 310 YRCLAENSLGS 320



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 344 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 400

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 401 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 453

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 454 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 510

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 511 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 570

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 571 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 608



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 256 QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 310

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 311 RCLAENSLGSARHAYYVTVE 330



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 333 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 388

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 389 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 445

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 446 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 498

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 499 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 236  IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 293

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 294  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 331



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 250  SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 304

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 305  EDDGEYRCLAENSLGSA 321



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 440 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 492

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 493 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 546

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 547 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 603

Query: 576 ARL 578
           A+L
Sbjct: 604 AQL 606



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 199  LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 255

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 256  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 312

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 313  LAENSLGSARHAYYVTVE 330



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 211  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 267

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 268  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 324

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 325  YYVTVEA 331



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 327  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 383

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 384  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 433



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 333  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 211  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 271  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 330

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 331  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 387

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 388  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 421



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 251  HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 305

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 306  DDGEYRCLAENSLGSA 321



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 244  FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 298

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 299  LLKVGEEDDGEYRCLAENSLG 319



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 426  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 479

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 480  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 516


>AY167726-1|AAO17629.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167725-1|AAO17628.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167724-1|AAO17627.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167723-1|AAO17626.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167722-1|AAO17625.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167721-1|AAO17624.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167720-1|AAO17623.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167719-1|AAO17622.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167718-1|AAO17621.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167717-1|AAO17620.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167716-1|AAO17619.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167715-1|AAO17618.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167714-1|AAO17617.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167713-1|AAO17616.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167712-1|AAO17615.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167711-1|AAO17614.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167710-1|AAO17613.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167709-1|AAO17612.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167708-1|AAO17611.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167707-1|AAO17610.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167706-1|AAO17609.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167705-1|AAO17608.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167704-1|AAO17607.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167703-1|AAO17606.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167702-1|AAO17605.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167701-1|AAO17604.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167700-1|AAO17603.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167699-1|AAO17602.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167698-1|AAO17601.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167697-1|AAO17600.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167696-1|AAO17599.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167695-1|AAO17598.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167694-1|AAO17597.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167693-1|AAO17596.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167692-1|AAO17595.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167691-1|AAO17594.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167690-1|AAO17593.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167689-1|AAO17592.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167688-1|AAO17591.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167687-1|AAO17590.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167686-1|AAO17589.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167685-1|AAO17588.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167684-1|AAO17587.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167683-1|AAO17586.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167682-1|AAO17585.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167681-1|AAO17584.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AY167680-1|AAO17583.1|  534|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 534

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 99   EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 154

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 155  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 204

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 205  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 262

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 263  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 307

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 308  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 358

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 359  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 415

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 416  SDQGNYSCVASTELDVVESRAQLLV 440



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 164 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 221

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 222 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 278

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 279 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 335

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 336 NNVTIMANL 344



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 78   TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 134

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 135  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 178

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 179  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 233

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 234  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 287

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 288  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 344

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 345  KVKDAT 350



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 180  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 238

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 239  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 288

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 289  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 344

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 345  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 388

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 389  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G+    +C   G P P + W      +  D     +  ++ N  L +  V   D G   
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMPADR----VTYQNHNKTLQLLKVGEEDDGEYR 143

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G       + V       AP ++ +  +     GE   L+ +  G P P +TW
Sbjct: 144 CLAENSLGSARHAYYVTV-----EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTW 198

Query: 525 QKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           + +G+P+     + +     GA  L +   + SD    QC A+N  G     A +Y
Sbjct: 199 RINGIPVEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIY 252



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 176 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 232

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 233 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 285

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 286 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 342

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 343 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 402

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 403 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 440



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 88  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 142

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 143 RCLAENSLGSARHAYYVTVE 162



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S L   +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D
Sbjct: 82  SHLVALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEED 138

Query: 558 AAWYQCTAQNVAGS 571
              Y+C A+N  GS
Sbjct: 139 DGEYRCLAENSLGS 152



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 165 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 220

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 221 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 277

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 278 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 330

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 331 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 372



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 68   IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 125

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 126  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 163



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 82   SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 136

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 137  EDDGEYRCLAENSLGSA 153



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 272 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 324

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 325 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 378

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 379 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 435

Query: 576 ARL 578
           A+L
Sbjct: 436 AQL 438



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 31   LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 87

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 88   QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 144

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 145  LAENSLGSARHAYYVTVE 162



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 99

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 100  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 156

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 157  YYVTVEA 163



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 159  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 215

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 216  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 265



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 165  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 202



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 43   AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 102

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 103  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 162

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 163  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 219

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 220  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 83   HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 137

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 138  DDGEYRCLAENSLGSA 153



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 76   FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 130

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 131  LLKVGEEDDGEYRCLAENSLG 151



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 258  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 311

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 312  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348


>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhesion
            molecule like-protein 1a protein.
          Length = 2053

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 91/366 (24%), Positives = 147/366 (40%), Gaps = 49/366 (13%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAK 4493
            G P+P I+W ++  P+     +      TK I  L I  +  EDS  +     N  G+A+
Sbjct: 251  GYPIPAIRWLKDGRPLPADSRW------TKRITGLTISDLRTEDSGTYICEVTNTFGSAE 304

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  L+V          I P   TLT + +    G  V L   +TG+    + W +N + 
Sbjct: 305  ATGILMV----------IDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTEL 354

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            V PD    I       TLLI  A    SG Y+C A   A  A+  A  +++L        
Sbjct: 355  VLPDEAISIRGLSNE-TLLITSAQKSHSGAYQCFATRKAQTAQDFA--IIALE------- 404

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI------KPSK 4667
                  +  P I+    +K+V  G+     C   G P PTV W   D+ I      + ++
Sbjct: 405  ------DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQ 458

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y     T   Y + ++     D G Y+C A N  G     A++ V  P      P++  +
Sbjct: 459  YTMSDGTTISY-MNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP------PSIRAM 511

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
            R+I    G+      ++      +I+W ++  L+P+    Q++ E N  + L       D
Sbjct: 512  RNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDN-HRQVVFE-NGTLKLTDVQKGMD 569

Query: 4788 TGTFTC 4793
             G + C
Sbjct: 570  EGEYLC 575



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 53/178 (29%), Positives = 79/178 (44%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C +TG P   + W+ N   +  D    I +    N  L+IT+   S SG   C
Sbjct: 329 GSTVILSCALTGSPEFTIRWYRNTELVLPD--EAISIRGLSNETLLITSAQKSHSGAYQC 386

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
            A  K+ +TA    +  +E      P+ V  FS   V  GE   L   A G P P +TW 
Sbjct: 387 FATRKA-QTAQDFAIIALEDG---TPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWA 442

Query: 526 KDGVPIIPNPELRIH----TDGGA-STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+ +   R +    +DG   S +++   +  D   Y+CTA+N+ GS   +AR+
Sbjct: 443 LDDEPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARI 500



 Score = 70.9 bits (166), Expect = 1e-10
 Identities = 48/177 (27%), Positives = 71/177 (40%), Gaps = 12/177 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHAL 450
           P+ V    ++ V  G+     C   G P P VTW ++D  I  D +H+      S    +
Sbjct: 408 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 467

Query: 451 MITNVT---LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
              NVT   + D GV  C ARN  G   +Q R+N      V  P  +     +    G  
Sbjct: 468 SYMNVTGPQIRDGGVYRCTARNLVGSAEYQARIN------VRGPPSIRAMRNITAVAGRD 521

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            ++N R +G P   I W KD + +  N    +  +G     D+   K  D   Y C+
Sbjct: 522 TLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDV--QKGMDEGEYLCS 576



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 91/426 (21%), Positives = 161/426 (37%), Gaps = 37/426 (8%)

Query: 4393 KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK 4452
            KAQT +      ++   P I +   +   V   EQ        G P P + W  ++ PI 
Sbjct: 391  KAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQFSLMCAAKGAPPPTVTWALDDEPIV 449

Query: 4453 NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
                 + + ++      I  + V    +        GG  +C+A  +V     Q R  + 
Sbjct: 450  RDGSHRTNQYTMSDGTTISYMNVTGPQI------RDGGVYRCTARNLVGSAEYQARINVR 503

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
             P      +N+   +G+   ++ +V G     + W K+   + PD   +++ E+GT  L 
Sbjct: 504  GPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGTLKLT 562

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
             ++    D G+Y C               V+  P           A   PP +I+P +  
Sbjct: 563  DVQK-GMDEGEYLC--------------SVLIQPQLSISQSVHV-AVKVPP-LIQPFEFP 605

Query: 4633 IVAEGQAIEFSCKIVGKPLPT-VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              + GQ +   C +    +P  + W K  ++I       +       +L+IS    +  G
Sbjct: 606  PASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNG 665

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            +  C+A N+A  V+   +L V  P +      + P     +Y G+       +     P 
Sbjct: 666  NDTCIASNAAATVSRERQLIVRVPPRF----VVQPNNQDGIY-GKAGVLNCSVDGYPPPK 720

Query: 4752 IQWLR-EGALIPE----TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG-QVETS 4805
            + W   +G+  P+     P    I    N+ LLI +  EED G + C+A+   G  +  S
Sbjct: 721  VMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKS 780

Query: 4806 AKLVVK 4811
              L VK
Sbjct: 781  MFLTVK 786



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 67/273 (24%), Positives = 107/273 (39%), Gaps = 27/273 (9%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS-GKYECVAINS-AGEARCDAECV 4602
            V W K+   + P+ R  I    G Y   I +   +D+   Y C+  +  +GE R      
Sbjct: 159  VSWEKDTVSIIPEHRFFITYHGGLY---ISDVQKEDALSTYRCITKHKYSGETRQSNGAR 215

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
            +S+          T  A + P I++    + V  G  +E  C   G P+P ++W K  + 
Sbjct: 216  LSV----------TDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRP 265

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
            +     +    T     L IS+   ED G Y C   N+ G       L V  P       
Sbjct: 266  LPADSRWTKRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHV---- 317

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG-NNAVLLIG 4781
             LTP + +    G        +T   + TI+W R   L+   PD  +   G +N  LLI 
Sbjct: 318  TLTP-KKLKTGIGSTVILSCALTGSPEFTIRWYRNTELV--LPDEAISIRGLSNETLLIT 374

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            +  +  +G + C AT  A   +  A + ++  T
Sbjct: 375  SAQKSHSGAYQCFATRKAQTAQDFAIIALEDGT 407



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 50/190 (26%), Positives = 79/190 (41%), Gaps = 16/190 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T  +CRV G PY  + W+  D  +  D NH+ +V E+G   L 
Sbjct: 505 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWY-KDALLLPD-NHRQVVFENGT--LK 560

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +T+V    D G   C           Q +L++ +   V    P  ++ F       G+ +
Sbjct: 561 LTDVQKGMDEGEYLC-------SVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLL 613

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +         P RITW+KDG  II    + I +    S+L I            C A N
Sbjct: 614 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASN 673

Query: 568 VAGSTATRAR 577
            A +T +R R
Sbjct: 674 -AAATVSRER 682



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 51/186 (27%), Positives = 78/186 (41%), Gaps = 15/186 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVT--GRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           P  V+V +D+    G +  F C +   G+ Y  V  +  D  +     H+  +   G   
Sbjct: 126 PYTVRV-EDQRSMRGNVAVFKCLIPFLGQEYVSVVSWEKDT-VSIIPEHRFFITYHGG-- 181

Query: 450 LMITNVTLSDS-GVVTCVARNK-SGETAFQ--CRLNVIEKEQVVAPKFVERFSTLNVREG 505
           L I++V   D+     C+ ++K SGET      RL+V +  + + P  ++ F +  V  G
Sbjct: 182 LYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESI-PTILDGFHSQEVWAG 240

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             V L   A G P P I W KDG P+  +        G    L I   +  D+  Y C  
Sbjct: 241 HTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG----LTISDLRTEDSGTYICEV 296

Query: 566 QNVAGS 571
            N  GS
Sbjct: 297 TNTFGS 302



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 67/291 (23%), Positives = 101/291 (34%), Gaps = 36/291 (12%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I W ++   I +     I +    S L I  V ++ +     +A N   T      L+V 
Sbjct: 628  ITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRERQLIVR 687

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK-----NGKKVQP 4556
                      VPP F +   N +   G+   L+  V G  P  V W       N ++  P
Sbjct: 688  ----------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHP 737

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
                  ++     +LLI     +D G Y C A N  G                D  K   
Sbjct: 738  VPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGT---------------DISKSMF 782

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS---KYFQMSR 4673
                 P  I       I  +G A E +C   G+    ++W KGD +I P    +Y   ++
Sbjct: 783  LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 842

Query: 4674 TADEYTLRISEAFPEDEGD---YKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
               +  +   +  P D GD   + C A NS G      +L V +P     L
Sbjct: 843  DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPEL 893



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 13/148 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W  +G+ + A  R  T    G+ + ++   +T DSGTY C  TN +G AE +  L  +
Sbjct: 257  IRWLKDGRPLPADSRW-TKRITGLTISDL---RTEDSGTYICEVTNTFGSAEATGILMVI 312

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            D      P   T     + LK G  +    +      P+  I WY N + +     I ++
Sbjct: 313  D------PLHVT--LTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI-SI 363

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229
                   L I   Q   SG Y C A  K
Sbjct: 364  RGLSNETLLITSAQKSHSGAYQCFATRK 391



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPIIPNPELR 538
            IE       K +    T+     + V L   +VG P P + W KD     +P+  +    
Sbjct: 1282 IEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRL 1341

Query: 539  IHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            IHT+G   TL +   KA D+ +Y CTA N  G
Sbjct: 1342 IHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1370



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 4/72 (5%)

Query: 791 EAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNK 850
           E   T    P   + W KDGRP+ A SR T         L I  LR ED+G+Y     N 
Sbjct: 244 ELPCTASGYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNT 299

Query: 851 LGEAISTASIRV 862
            G A +T  + V
Sbjct: 300 FGSAEATGILMV 311



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLKDGRP+ A SR T         LTI  +   D+G Y C   N  G A  +  L ++
Sbjct: 257  IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 312



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 53/246 (21%), Positives = 103/246 (41%), Gaps = 16/246 (6%)

Query: 338 LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
           LL +N    +  +G L +    +   + +    +    Q    + + ++ K   P  ++ 
Sbjct: 544 LLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKV--PPLIQP 601

Query: 398 CQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            +    + G++    C V+    P  +TW   D Q+    +   + ++    +L I++V+
Sbjct: 602 FEFPPASIGQLLYIPCVVSSGDMPIRITWR-KDGQVIISGSGVTIESKEFMSSLQISSVS 660

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
           L  +G  TC+A N +   + + +L V      V P+FV + +  +   G+  VLN    G
Sbjct: 661 LKHNGNDTCIASNAAATVSRERQLIVR-----VPPRFVVQPNNQDGIYGKAGVLNCSVDG 715

Query: 517 TPTPRITWQK---DGVPIIPNP---ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P P++ W+     G P   +P     RI     +S L I      D  +Y C A N  G
Sbjct: 716 YPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL-IRHVLEEDIGYYLCQASNGVG 774

Query: 571 STATRA 576
           +  +++
Sbjct: 775 TDISKS 780



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 49/189 (25%), Positives = 72/189 (38%), Gaps = 14/189 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI----LVNESGN 447
           P+FV    ++D   GK    +C V G P P+V W            H +     +    N
Sbjct: 690 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 749

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            +L+I +V   D G   C A N  G    +     ++    +        +T    +G  
Sbjct: 750 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVK----IPAMITSHPNTTIAIKGHA 805

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELR--IHT-DGG---ASTLDIPRAKASDAAWY 561
             LN  A G     I W+K    I P+  +R  I T D G    STL +  A   D+ ++
Sbjct: 806 KELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFF 865

Query: 562 QCTAQNVAG 570
            C A N  G
Sbjct: 866 SCHAINSYG 874



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
            EV  GH V L  T +    P +R  W  +GRP+    R+ T    G    D+     ED+
Sbjct: 236  EVWAGHTVELPCTASGYPIPAIR--WLKDGRPLPADSRW-TKRITGLTISDLR---TEDS 289

Query: 2048 GTYMCKATNAVGEAVTTSSVKV 2069
            GTY+C+ TN  G A  T  + V
Sbjct: 290  GTYICEVTNTFGSAEATGILMV 311



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 17/162 (10%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L+IR V  ED   +   A N  GT   S ++ +  K        +P   T        
Sbjct: 750  SSLLIRHVLEEDIGYYLCQASNGVGT-DISKSMFLTVK--------IPAMITSHPNTTIA 800

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD--IRNKILEED-GTYTLLILEAYPQDSG 4582
              G    L+    G +PI + W K    + PD  +R  I  +D G   +  L+  P D G
Sbjct: 801  IKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRG 860

Query: 4583 K---YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
                + C AINS GE R   +  V  P   D P+ + +   A
Sbjct: 861  DSVFFSCHAINSYGEDRGLIQLTVQEP--PDPPELEIREVKA 900



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 44/185 (23%), Positives = 82/185 (44%), Gaps = 20/185 (10%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            S GQ+  Y   ++ +GD  + I W  +G+ I +   +       M  L+I       +G 
Sbjct: 608  SIGQLL-YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGN 666

Query: 3121 YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
             +C A+N    A +S + + + +     PRF     N +G+  G++    C+V     P 
Sbjct: 667  DTCIASN--AAATVSRERQLIVR---VPPRFVVQPNNQDGIY-GKAGVLNCSVDGYPPP- 719

Query: 3181 MKIEWYH---NGQPMRH-----STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             K+ W H   +G P ++     + RI+ + +   +   I +    D G Y+C+A N  G 
Sbjct: 720  -KVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL---IRHVLEEDIGYYLCQASNGVGT 775

Query: 3233 DFTRA 3237
            D +++
Sbjct: 776  DISKS 780



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 6/76 (7%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G  +   C    S  P   I W  + +PLP+ +R+          L I+    EDSG Y 
Sbjct: 240  GHTVELPCTA--SGYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYI 293

Query: 2848 CKATNSKGSATTSGSL 2863
            C+ TN+ GSA  +G L
Sbjct: 294  CEVTNTFGSAEATGIL 309



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 57/275 (20%), Positives = 98/275 (35%), Gaps = 17/275 (6%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVSLLIKQIGPG--DEGEYTCTARNQY 152
           +G P P V+W     P+V    + + +Y    G     +   GP   D G Y CTARN  
Sbjct: 432 KGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLV 491

Query: 153 GEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
           G A     I   G                    +  +  G   Y+ +  +    +     
Sbjct: 492 GSAEYQARINVRGPPSIRAMRNITAVAGR-DTLINCRVIGYPYYSIKWYKDALLL----- 545

Query: 213 TDHSSTDDFKVDTFEYRLLREVSFRESITK-RYVGESDVQISTEIDRSLG-PVSPPKIAQ 270
                 D+ +   FE   L+    ++ + +  Y+    +Q    I +S+   V  P + Q
Sbjct: 546 -----PDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQ 600

Query: 271 KPRNSKLQEGADAQFQVQLSGNPRP-RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQ 329
                    G        +S    P R+TW K+GQ +I+ +   I +    ++L++ +  
Sbjct: 601 PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVS 660

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
              +G+ T +A N    +     L V  P    VQ
Sbjct: 661 LKHNGNDTCIASNAAATVSRERQLIVRVPPRFVVQ 695



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            + W  + +PL + SR+T+        L I     EDSGTY C   N  G A  +GI +V
Sbjct: 257  IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMV 311



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   I WLK+G+ + A SR+T         L +  L  +DSG Y C   +  G AE  
Sbjct: 251 GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 306

Query: 724 AVLHV 728
            +L V
Sbjct: 307 GILMV 311



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 9/110 (8%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV  PP+F+ Q  +      +     C V+    PK  + W ++ K   +  +Y  V   
Sbjct: 685  IVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPK--VMW-KHAKGSGNPQQYHPVPLT 741

Query: 3885 GFV------SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            G +      SL I +V  ED G Y+C+A N  G D +K+     K+P +I
Sbjct: 742  GRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 791



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/135 (24%), Positives = 51/135 (37%), Gaps = 13/135 (9%)

Query: 1276 VTDTQNEQAIEQIQLL-----EDAARRTKQVREDIT--VMQAPQFSRALHNIETVEGTNV 1328
            ++D Q E A+   + +         R++   R  +T      P      H+ E   G  V
Sbjct: 184  ISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTV 243

Query: 1329 HLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT 1388
             L C     G     + W  +G+P+    R+          L +  +  EDSG Y C+ T
Sbjct: 244  ELPCTAS--GYPIPAIRWLKDGRPLPADSRWTKRI----TGLTISDLRTEDSGTYICEVT 297

Query: 1389 NQLGEAVTSCALRVI 1403
            N  G A  +  L VI
Sbjct: 298  NTFGSAEATGILMVI 312



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++G P+ A +R T         L +  +  EDSGTY C   N  G A  +
Sbjct: 251  GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEAT 306

Query: 1798 STLFV 1802
              L V
Sbjct: 307  GILMV 311



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            I W K+G  L   +R        +  L+I+ LR +DSG Y C+ TN  G A +T  + + 
Sbjct: 257  IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 312

Query: 2736 D 2736
            D
Sbjct: 313  D 313



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 4/135 (2%)

Query: 3800 PQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            PQ   G   +   R  +  A  +  I    P  I  +++ T          CRV     P
Sbjct: 475  PQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGY--P 532

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               I+WY++  LLP  HR + V++ G + L  +     D GEY+C  +       +++  
Sbjct: 533  YYSIKWYKDALLLPDNHR-QVVFENGTLKLTDVQ-KGMDEGEYLCSVLIQPQLSISQSVH 590

Query: 3920 SCKKLPDIILQNQVP 3934
               K+P +I   + P
Sbjct: 591  VAVKVPPLIQPFEFP 605



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 3/105 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P +   A  G  ++    +   GD  ++I W K+GQ I + S  T   +    SL
Sbjct: 596 PPLIQPFEFPPASIGQLLYIPCVVSS-GDMPIRITWRKDGQVIISGSGVTIESKEFMSSL 654

Query: 697 DMLSLNIQDSGEYTCRA--VSATGVAETKAVLHVTPRATIERTSQ 739
            + S++++ +G  TC A   +AT   E + ++ V PR  ++  +Q
Sbjct: 655 QISSVSLKHNGNDTCIASNAAATVSRERQLIVRVPPRFVVQPNNQ 699



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/174 (23%), Positives = 64/174 (36%), Gaps = 13/174 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W+ N + +     I ++       L I   + + SG Y C AT K   A+ 
Sbjct: 339  TGSPEFTIRWYRNTELVLPDEAI-SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 397

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-- 3192
               +   D +      F+  + N      G+     C       P   + W  + +P+  
Sbjct: 398  FAIIALEDGTPRIVSSFSEKVVN-----PGEQFSLMCAAKGAPPPT--VTWALDDEPIVR 450

Query: 3193 --RHSTRIKTVSDFGFV-VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
               H T   T+SD   +  +++   Q  D G Y C A N  G    +A IN  G
Sbjct: 451  DGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG 504



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 4436 GEPLPLIKWYREN----FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
            G+P P +KW +++     P+       IHT  T   L++R V  EDS  +   A N GG 
Sbjct: 1315 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT---LLLRAVKAEDSGYYTCTATNTGGF 1371

Query: 4492 AKCSANLVVEEKRRQGR 4508
                 NL+V+    Q R
Sbjct: 1372 DTIIVNLLVQVPPDQPR 1388



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 5/101 (4%)

Query: 3441 EARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNN 3500
            E   T +  P   + W  +G+ L A SR+          L IS    EDSG Y+C   N 
Sbjct: 244  ELPCTASGYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNT 299

Query: 3501 YGEAVTTASMKVQGKRNIIL-ESQLPKGMEGTIDKIAALEG 3540
            +G A  T  + V    ++ L   +L  G+  T+    AL G
Sbjct: 300  FGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTG 340



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/81 (25%), Positives = 37/81 (45%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD  +R+ W KDG+ + + S +T        +L I SV++   G+ TC A NA    +  
Sbjct: 622  GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRE 681

Query: 997  ANLTIVTKKDIIAESQHPGGL 1017
              L +      + +  +  G+
Sbjct: 682  RQLIVRVPPRFVVQPNNQDGI 702



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/124 (22%), Positives = 47/124 (37%), Gaps = 1/124 (0%)

Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
           S E    L  + P  +   P+  K   G+       L+G+P   + W++N + ++     
Sbjct: 302 SAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI 361

Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYIT 372
            I    N T L + + QKS SG Y   A            +A+E  T   V     + + 
Sbjct: 362 SIRGLSNETLL-ITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVN 420

Query: 373 DTQQ 376
             +Q
Sbjct: 421 PGEQ 424



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/104 (32%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG--DKLIKPSKY-FQMSRT 4674
            A  AP +II           + +   C  VG P P V+W K   D  I  S    ++  T
Sbjct: 1285 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHT 1344

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQ 4717
                 LR  +A  ED G Y C A N+ G  T+   L V   PDQ
Sbjct: 1345 NGTLLLRAVKA--EDSGYYTCTATNTGGFDTIIVNLLVQVPPDQ 1386



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 282  DAQFQVQLSGNPRPRVTWFKNGQRL---INSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            D +      G+P P V W K+ +     ++ + H +I  H + TL +R  +  DSG+YT 
Sbjct: 1306 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLI--HTNGTLLLRAVKAEDSGYYTC 1363

Query: 339  LAENPNGCIVTSGYLAVESPTE 360
             A N  G       L V+ P +
Sbjct: 1364 TATNTGGFDTIIVNLLVQVPPD 1385



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 9/90 (10%)

Query: 1471 VTDSNLKVEWFKNGQ----PVTI-GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525
            V D    V+W K+ +    PV++ GHR   IH  G + L  +   AEDSG YTC A N  
Sbjct: 1314 VGDPAPAVKWTKDSEDSAIPVSMDGHRL--IHTNGTLLLRAVK--AEDSGYYTCTATNTG 1369

Query: 1526 GTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555
            G D +   L  +   D  R T ++     I
Sbjct: 1370 GFDTIIVNLLVQVPPDQPRLTVSKTSASSI 1399



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 40/173 (23%), Positives = 71/173 (41%), Gaps = 14/173 (8%)

Query: 3063 GQIAHYEASLIPTGDQSM-VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121
            G +A ++  +   G + + V+ W  +  +I   HR    Y  G+ + ++   K     TY
Sbjct: 139  GNVAVFKCLIPFLGQEYVSVVSWEKDTVSIIPEHRFFITYHGGLYISDV--QKEDALSTY 196

Query: 3122 SCRATNKW-GQAEIS--VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
             C   +K+ G+   S   +L   D ++   P       + E +  G +    CT      
Sbjct: 197  RCITKHKYSGETRQSNGARLSVTDPAESI-PTILDGFHSQE-VWAGHTVELPCTASGYPI 254

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            P   I W  +G+P+   +R  T    G  + D+   +  DSG Y+C   N +G
Sbjct: 255  P--AIRWLKDGRPLPADSRW-TKRITGLTISDL---RTEDSGTYICEVTNTFG 301



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-- 3870
            RG  S+    EP    P K I+   + T    + VR  C      DP   ++W ++ +  
Sbjct: 1273 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCN--SVGDPAPAVKWTKDSEDS 1330

Query: 3871 LLP-SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             +P S   +R ++  G  +L +  V AEDSG Y C A N  G D     +  +  PD
Sbjct: 1331 AIPVSMDGHRLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPD 1385



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 6/77 (7%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            +V  G  V   C     G P   I W  +GRP    SR  T    G   L I  +   D+
Sbjct: 236  EVWAGHTVELPCTAS--GYPIPAIRWLKDGRPLPADSR-WTKRITG---LTISDLRTEDS 289

Query: 3766 GEYTCRATNKWGSATTT 3782
            G Y C  TN +GSA  T
Sbjct: 290  GTYICEVTNTFGSAEAT 306



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G T    C     G P   + W ++ + +   SR TK        +TIS +R ED G Y+
Sbjct: 240  GHTVELPCTAS--GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYI 293

Query: 2451 CRASNLLG 2458
            C  +N  G
Sbjct: 294  CEVTNTFG 301



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 5/120 (4%)

Query: 240 ITK-RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT 298
           ITK +Y GE+       +  +    S P I     + ++  G   +     SG P P + 
Sbjct: 199 ITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIR 258

Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           W K+G+ L   ++     T   T L + + +  DSG Y     N  G    +G L V  P
Sbjct: 259 WLKDGRPLPADSR----WTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 314



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +    C    YP P +R  W  +G+ L +  R+ T    G    D+ T   EDSG Y 
Sbjct: 240  GHTVELPCTASGYPIPAIR--WLKDGRPLPADSRW-TKRITGLTISDLRT---EDSGTYI 293

Query: 1919 CKAINNLGQA 1928
            C+  N  G A
Sbjct: 294  CEVTNTFGSA 303



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 9/103 (8%)

Query: 53  ESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL 112
           +S+G R  +T   P E  P I +       +A G   +      G P P + W +   PL
Sbjct: 210 QSNGARLSVTD--PAESIPTILDGFHSQEVWA-GHTVELPCTASGYPIPAIRWLKDGRPL 266

Query: 113 VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
              ++++ R    TG   L I  +   D G Y C   N +G A
Sbjct: 267 PADSRWTKRI---TG---LTISDLRTEDSGTYICEVTNTFGSA 303



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 6/82 (7%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  +    S  V     V   C       P +R  W ++G+ LP+  R+          L
Sbjct: 226  PTILDGFHSQEVWAGHTVELPCTASGYPIPAIR--WLKDGRPLPADSRWTK----RITGL 279

Query: 3890 DILYVYAEDSGEYICRAVNDFG 3911
             I  +  EDSG YIC   N FG
Sbjct: 280  TISDLRTEDSGTYICEVTNTFG 301



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
            G P   + W  +G+PL   +R+T         +    +  EDSG Y+C  TN +G  E  
Sbjct: 251  GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 306

Query: 4061 AVI 4063
             ++
Sbjct: 307  GIL 309



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W  +G+ + A  R+ T    G    D+     EDSGTY+C+ TN  G A  T  
Sbjct: 253  PIPAIRWLKDGRPLPADSRW-TKRITGLTISDLR---TEDSGTYICEVTNTFGSAEATGI 308

Query: 2199 LKVAGHRNIIL 2209
            L V    ++ L
Sbjct: 309  LMVIDPLHVTL 319



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 4/54 (7%)

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            + W K+G+P+    R+          L I DL  EDSG Y C   N  G+ E +
Sbjct: 257  IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 306



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLL----HK-NRFTPIYDFGYVAMNFGWVYPEDSGEY 4046
            +F    A  G P   V W  + +P++    H+ N++T         MN       D G Y
Sbjct: 424  QFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVY 483

Query: 4047 LCRATNLYGMDETKAVIKTTGKPGI 4071
             C A NL G  E +A I   G P I
Sbjct: 484  RCTARNLVGSAEYQARINVRGPPSI 508



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PPRFV Q  +Q  +   +     C +   G P  KV W  + K   +  ++ P+   G +
Sbjct: 689  PPRFVVQPNNQDGIYG-KAGVLNCSVD--GYPPPKVMWK-HAKGSGNPQQYHPVPLTGRI 744

Query: 4032 ------AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                  ++    V  ED G YLC+A+N  G D +K++  T   P ++
Sbjct: 745  QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 791



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 18/122 (14%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMP-MKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
            R N  E  +      A  ++I+     T P MKD+R+  N           VGDP   V+
Sbjct: 1273 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNS----------VGDPAPAVK 1322

Query: 1746 WLRNG----VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
            W ++     +P+        +H  G   L ++ V  EDSG YTC A N  G       L 
Sbjct: 1323 WTKDSEDSAIPVSMDGH-RLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLL 1379

Query: 1802 VQ 1803
            VQ
Sbjct: 1380 VQ 1381



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKDGR----PVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD    V+W KD      PV          N     L +++V   D+G+YTC A N  G
Sbjct: 1314 VGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1370

Query: 992  QATTSANLTIVTKKD 1006
              T   NL +    D
Sbjct: 1371 FDTIIVNLLVQVPPD 1385


>AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecule
            protein.
          Length = 1255

 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 104/385 (27%), Positives = 163/385 (42%), Gaps = 52/385 (13%)

Query: 4435 DGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P P IKW R + P+  +   +Q H    K++ +++ V  ED   +  +AEN  G+A+
Sbjct: 265  EGFPTPTIKWLRPSGPMPADRVTYQNHN---KTLQLLK-VGEEDDGEYRCLAENSLGSAR 320

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  + VE            P +    Q+     G+  RLD +V G    +V W  NG  
Sbjct: 321  HAYYVTVE----------AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 370

Query: 4554 VQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC-VVSLPATKDK 4611
            V+   ++ K   + G   L++    P D+   +C A N  G    +A   VV LPA    
Sbjct: 371  VEELAKDQKYRIQRGA--LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 428

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK--GDKLIKPSKYF 4669
               QT  A                +G      CK  G P+P+VQW    G  +++  ++F
Sbjct: 429  ADNQTYMA---------------VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFF 473

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
              +      TL I +    D G Y C+A N    VT+ A LKV    Q    P     R 
Sbjct: 474  PYANG----TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGP-----RS 524

Query: 4730 IVVYEGQPAQFKTQIT--SKIKPTIQWLREGALIPETPDFQ--MIHEGNNAVLLIGNTYE 4785
             +  +G    F  Q +    ++P+I W  +G  + E  D     I +G    L+I +   
Sbjct: 525  TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR---LVIHSLDY 581

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G ++C A+T    VE+ A+L+V
Sbjct: 582  SDQGNYSCVASTELDVVESRAQLLV 606



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 56/189 (29%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP ++   Q      G+  R DC+V GRP PEVTW IN   + +    +    + G  AL
Sbjct: 330 APYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRG--AL 387

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +++NV  SD+ V  C ARN+ G       + V+   Q+ A        T    +G    L
Sbjct: 388 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYL 444

Query: 511 NARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +A G P P + W  +DG  ++ +     + +G   TL I   +A+D   Y C A N  
Sbjct: 445 LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG---TLGIRDLQANDTGRYFCLAANDQ 501

Query: 570 GSTATRARL 578
            +    A L
Sbjct: 502 NNVTIMANL 510



 Score = 60.9 bits (141), Expect = 1e-07
 Identities = 80/306 (26%), Positives = 120/306 (39%), Gaps = 41/306 (13%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            T ++ ++    GQ + L+    G     + WL+    +  D   ++  ++   TL +L+ 
Sbjct: 244  TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKV 300

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
              +D G+Y C+A NS G AR  A  V    A     KPQ+                +   
Sbjct: 301  GEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQS---------------HLYGP 344

Query: 4637 GQAIEFSCKIVGKPLPTVQW-YKG---DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G+     C++ G+P P V W   G   ++L K  KY ++ R A    L +S   P D   
Sbjct: 345  GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY-RIQRGA----LILSNVQPSDTMV 399

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY---EGQPAQFKTQITSKIK 4749
             +C A N  G +   A + V Q      LPA     D   Y   +G  A    +      
Sbjct: 400  TQCEARNRHGLLLANAYIYVVQ------LPAKILTADNQTYMAVQGSTAYLLCKAFGAPV 453

Query: 4750 PTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P++QWL E G  + +   F       N  L I +    DTG + C A      V   A L
Sbjct: 454  PSVQWLDEDGTTVLQDERF---FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANL 510

Query: 4809 VVKSKT 4814
             VK  T
Sbjct: 511  KVKDAT 516



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 77/297 (25%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            E AR + +  G P P + W     P++     Q +    +  LI+  V   D+ V    A
Sbjct: 346  ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEA 404

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPI 4543
             NR G    +A + V          +  P+  LTA N       G    L  K  G    
Sbjct: 405  RNRHGLLLANAYIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 454

Query: 4544 DVYWL-KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V WL ++G  V  D R      +GT  +  L+A   D+G+Y C+A N        A   
Sbjct: 455  SVQWLDEDGTTVLQDER-FFPYANGTLGIRDLQA--NDTGRYFCLAANDQNNVTIMANL- 510

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP--LPTVQWYKGD 4660
                    K K  T+    P   IE        +G  + F+C+    P   P++ W +GD
Sbjct: 511  --------KVKDATQITQGPRSTIE-------KKGSRVTFTCQASFDPSLQPSITW-RGD 554

Query: 4661 -----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 +L    KYF      ++  L I      D+G+Y CVA      V   A+L V
Sbjct: 555  GRDLQELGDSDKYF-----IEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 606



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 50/191 (26%), Positives = 78/191 (40%), Gaps = 15/191 (7%)

Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           AP++ K   +  +V EG+     C       P   +++N + +    + ++ + ++GN  
Sbjct: 133 APKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGN-- 190

Query: 450 LMITNVTLSDS-GVVTCVARNKSGETAFQCR---LNVIEKEQVVAPKFVERFST-----L 500
           L   NV  SD+     C A      T  Q     L V     ++  K    F T     L
Sbjct: 191 LYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHL 250

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              +G+P+VL   A G PTP I W +   P  P P  R+       TL + +    D   
Sbjct: 251 VALQGQPLVLECIAEGFPTPTIKWLR---PSGPMPADRVTYQNHNKTLQLLKVGEEDDGE 307

Query: 561 YQCTAQNVAGS 571
           Y+C A+N  GS
Sbjct: 308 YRCLAENSLGS 318



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 114/282 (40%), Gaps = 26/282 (9%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           +  G  A+ + +++G P P V+W     P+ E  K   +Y  Q G  +L++  + P D  
Sbjct: 342 YGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK-DQKYRIQRG--ALILSNVQPSDTM 398

Query: 143 EYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH---KAYGTQGYTTE 199
              C ARN++G  + + YI                 Y  V  +  +   KA+G       
Sbjct: 399 VTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGA------ 451

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG-ESDVQISTEIDR 258
                  V + +    +   D +   +    L     + + T RY    ++ Q +  I  
Sbjct: 452 ---PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMA 508

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP--RPRVTWFKNG---QRLINSNKHE 313
           +L      +I Q PR++  ++G+   F  Q S +P  +P +TW  +G   Q L +S+K+ 
Sbjct: 509 NLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYF 568

Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           I        L + +   SD G+Y+ +A      + +   L V
Sbjct: 569 I----EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV 606



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           QG     E    G PTP + W R   P+      + R   Q  + +L + ++G  D+GEY
Sbjct: 254 QGQPLVLECIAEGFPTPTIKWLRPSGPMP-----ADRVTYQNHNKTLQLLKVGEEDDGEY 308

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A N  G A  + Y+  E
Sbjct: 309 RCLAENSLGSARHAYYVTVE 328



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 54/222 (24%), Positives = 88/222 (39%), Gaps = 22/222 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG---QRLINSNKHEIITTHNHTT 322
           P    KP++     G  A+   Q+ G P+P VTW  NG   + L    K+ I        
Sbjct: 331 PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI----QRGA 386

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYL-AVESPTESYVQDQRSQYITDTQQRETEE 381
           L + N Q SD+      A N +G ++ + Y+  V+ P +    D ++ Y+    Q  T  
Sbjct: 387 LILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT-YM--AVQGSTAY 443

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +  +  A  P  V+   +   T  +  RF       PY   T  I D Q  D   +  L
Sbjct: 444 LLCKAFGAPVPS-VQWLDEDGTTVLQDERF------FPYANGTLGIRDLQANDTGRYFCL 496

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARN----KSGETAFQCR 479
                N+  ++ N+ + D+  +T   R+    K     F C+
Sbjct: 497 AANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 538



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 1840 VNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTS 1896
            +++ PR +   N  + L   +GQ    EC  E +P P   ++W   +G +      Y+  
Sbjct: 234  IDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPADRVTYQNH 291

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            N      L +L V  ED GEY C A N+LG A  +  + V++
Sbjct: 292  NK----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA 329



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +++V  +G  +  EC  E    PT+K  W   + P+P+       H+    +L +    E
Sbjct: 248  SHLVALQGQPLVLECIAEGFPTPTIK--WLRPSGPMPADRVTYQNHN---KTLQLLKVGE 302

Query: 2841 EDSGIYTCKATNSKGSA 2857
            ED G Y C A NS GSA
Sbjct: 303  EDDGEYRCLAENSLGSA 319



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 25/183 (13%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES----GNHALMITNVTLSDS 460
           +G      C+  G P P V W        D+    +L +E      N  L I ++  +D+
Sbjct: 438 QGSTAYLLCKAFGAPVPSVQWL-------DEDGTTVLQDERFFPYANGTLGIRDLQANDT 490

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPT 519
           G   C+A N          L V +  Q+   P+     ST+  ++G  V    +A   P+
Sbjct: 491 GRYFCLAANDQNNVTIMANLKVKDATQITQGPR-----STIE-KKGSRVTFTCQASFDPS 544

Query: 520 --PRITWQKDGVPI--IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
             P ITW+ DG  +  + + +     DG    L I     SD   Y C A        +R
Sbjct: 545 LQPSITWRGDGRDLQELGDSDKYFIEDG---RLVIHSLDYSDQGNYSCVASTELDVVESR 601

Query: 576 ARL 578
           A+L
Sbjct: 602 AQL 604



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 6/138 (4%)

Query: 999  LTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
            LT     D I  +  PG    IQ  E      K T     I +KPR L P   ++ +V  
Sbjct: 197  LTSDNHSDYICHAHFPGTRTIIQK-EPIDLRVKATNS--MIDRKPRLLFPTNSSSHLVAL 253

Query: 1059 QSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTV 1118
            Q          +   T T++W      +  A+R+ TY +     L +  V  ED G Y  
Sbjct: 254  QGQPLVLECIAEGFPTPTIKWLRPSGPMP-ADRV-TYQNHNKT-LQLLKVGEEDDGEYRC 310

Query: 1119 VARNAAGEAQLSASMTVE 1136
            +A N+ G A+ +  +TVE
Sbjct: 311  LAENSLGSARHAYYVTVE 328



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 6/127 (4%)

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
            +HF      IQK    L  +   ++ D KP    F      ++   +G P+  +C  E  
Sbjct: 209  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL-LFPTNSSSHLVALQGQPLVLECIAE-- 265

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  I W     P     RV   N      L +  +   D GEY C A N  GSA   
Sbjct: 266  GFPTPTIKWLRPSGPMPA-DRVTYQNHNK--TLQLLKVGEEDDGEYRCLAENSLGSARHA 322

Query: 3783 AKITCSA 3789
              +T  A
Sbjct: 323  YYVTVEA 329



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV  AP +     +     G    L+C++Q  G     V W  NG P++   + +  Y 
Sbjct: 325  VTVEAAPYWLHKPQSHLYGPGETARLDCQVQ--GRPQPEVTWRINGIPVEELAKDQK-YR 381

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
                AL L +V P D+ V  C+A N+ G  + +  + V+     IL + +
Sbjct: 382  IQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADN 431



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            P ++  P +     GE AR  C+V G P+P V W +NG
Sbjct: 331  PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 368



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 9/214 (4%)

Query: 1595 AHFE--RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALD----IMSCLPEDSG 1648
            AHF   R +I      L+V+  ++    K    F   ++   VAL     ++ C+ E   
Sbjct: 209  AHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 268

Query: 1649 TYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVIT 1708
            T T + +   G      +   +  K++ L    E        L + S      A    + 
Sbjct: 269  TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 328

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             AP +    +       + A  + ++   G P+  V W  NG+P+E   +    +     
Sbjct: 329  AAPYWLHKPQSHLYGPGETARLDCQV--QGRPQPEVTWRINGIPVEELAK-DQKYRIQRG 385

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            AL +  V P D+    C A N  G  + ++ ++V
Sbjct: 386  ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 419



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            ++  ++G  + LEC  +  G  T  ++W     P+      R  Y+     L LL V  E
Sbjct: 249  HLVALQGQPLVLECIAE--GFPTPTIKWLRPSGPMPAD---RVTYQNHNKTLQLLKVGEE 303

Query: 1379 DSGVYTCQATNQLGEA 1394
            D G Y C A N LG A
Sbjct: 304  DDGEYRCLAENSLGSA 319



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 3832 FITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLD 3890
            F T   SH V  + + +  EC  E    P   I+W R    +P+    R  Y     +L 
Sbjct: 242  FPTNSSSHLVALQGQPLVLECIAEGFPTPT--IKWLRPSGPMPAD---RVTYQNHNKTLQ 296

Query: 3891 ILYVYAEDSGEYICRAVNDFG 3911
            +L V  ED GEY C A N  G
Sbjct: 297  LLKVGEEDDGEYRCLAENSLG 317



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF-KNGVTLTTGARLKSTFDFGL 2699
            A I T   ++Y   V+G   YL  +      P+  ++W  ++G T+    R    F +  
Sbjct: 424  AKILTADNQTY-MAVQGSTAYLLCKAFGAPVPS--VQWLDEDGTTVLQDERF---FPYAN 477

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I  L+ +D+G Y C A N        A++K++D
Sbjct: 478  GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 514


>X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein.
          Length = 1142

 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 106/430 (24%), Positives = 178/430 (41%), Gaps = 53/430 (12%)

Query: 4398 ERVVEGPVKPSKPPIFTKKMQPC-RVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD 4456
            +R+ +  V+  K   FTKK+ P  +V    + +  VE     L L KW++    IK S  
Sbjct: 243  KRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTL-KWFKNGQEIKPSSK 301

Query: 4457 FQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
            +       K IL I +  + D A +    ++     KC   L V+E          PP  
Sbjct: 302  YVFENVGKKRILTINKCTLADDAAYEVAVKDE----KCFTELFVKE----------PPVL 347

Query: 4517 TLTA-QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI---LEEDGTYTLL 4572
             +T  ++  V  G  V +  +V+  +   V W+K+G ++  +   K     ++DG   +L
Sbjct: 348  IVTPLEDQQVFVGDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHIL 406

Query: 4573 IL-EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
            I  +   +D G+Y+   I + G+  C+AE +V     ++K            E+++ + D
Sbjct: 407  IFSDVVQEDRGRYQ--VITNGGQ--CEAELIV-----EEKQL----------EVLQDIAD 447

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              V   +   F C++  + + T +WYK    ++PSK   +S     + L I +  PEDEG
Sbjct: 448  LTVKASEQAVFKCEVSDEKV-TGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506

Query: 4692 DYKCV----AYNSAGRVTVAAKLKVTQ-PDQAD-----NLPALTPLRDIVVYEGQPAQFK 4741
            DY  V    A  S        ++KV   P Q       +    T    IVV  G   +  
Sbjct: 507  DYTFVPDGYALGSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLD 566

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEG-NNAVLLIGNTYEEDTGTFTCRATTAAG 4800
              IT +  P   WL+   +   T     I +  + +  +I +   ED G +T + T   G
Sbjct: 567  VSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG 626

Query: 4801 QVETSAKLVV 4810
            +   S  L V
Sbjct: 627  EDVASIFLQV 636



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 146/652 (22%), Positives = 243/652 (37%), Gaps = 62/652 (9%)

Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHP---KPRVMWLLNGNTIVNGSRYKLTYDGMYHFD 4168
            VF+  PD+V+VE G+ A    +V G     KP + W   G  +  GS+        + F 
Sbjct: 53   VFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWF-KGKWLELGSKS----GARFSFK 107

Query: 4169 IPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHD-DYRGVLKNAPRPWYDETTQYQRT 4227
                   +   +E+              L+V  +   D  G   +   P  D + Q   +
Sbjct: 108  ESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLES 167

Query: 4228 ETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQEL-EN 4286
                ++T E++      G +D    LK + + E E +     K+KK+++      E+ E 
Sbjct: 168  ---FKRTSEKKS--DTAGELDFSGLLKKREVVEEEKK-----KKKKDDDDLGIPPEIWEL 217

Query: 4287 EQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQ-----RYEDNLDQTEEVTEQRVQKKV 4341
             +  K+S   +   QY I   +     + K+  +      +   LD   +V       K+
Sbjct: 218  LKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGN---KI 274

Query: 4342 TQKPRIPDPSESTVHGKEVHVAKQKQTQK-EVVGDKEIT--RKITSTETTEIEHKAQTQE 4398
                 I DP  +    K     K       E VG K I    K T  +    E   + ++
Sbjct: 275  KLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEK 334

Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ 4458
               E  VK   P +    ++  +VF  ++    VE   E   ++ W ++   +     F+
Sbjct: 335  CFTELFVK-EPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVM-WMKDGVELTREDSFK 392

Query: 4459 I-HTFST---KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP 4514
              + F     + ILI   V  ED   +  +    GG  +C A L+VEEK+ +    I   
Sbjct: 393  ARYRFKKDGKRHILIFSDVVQEDRGRYQVITN--GG--QCEAELIVEEKQLEVLQDIA-- 446

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLIL 4574
              T+ A    V   ++   D KVTG       W KNG +V+P  R  I      + L+I 
Sbjct: 447  DLTVKASEQAVFKCEVS--DEKVTGK------WYKNGVEVRPSKRITISHVGRFHKLVID 498

Query: 4575 EAYPQDSGKYECV----AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            +  P+D G Y  V    A+ S        E  V     ++ PK     +    E      
Sbjct: 499  DVRPEDEGDYTFVPDGYALGSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSE-----N 553

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK-YFQMSRTADEYTLRISEAFPED 4689
              +V  G  +     I G+P P   W KGD++   ++   ++ +  D  +  I  A  ED
Sbjct: 554  AIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQRED 613

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADNLPALTPLRDIVVYEGQPAQF 4740
            EG Y     N  G    +  L+V   PD  + +   +   D  +   +P  +
Sbjct: 614  EGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMY 665



 Score = 65.3 bits (152), Expect = 5e-09
 Identities = 68/295 (23%), Positives = 111/295 (37%), Gaps = 15/295 (5%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            EQ    V F G+P P + W +   P+  S    + T    ++  +RQ    DS  +    
Sbjct: 857  EQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-VHVRTSDFDTVFFVRQAARSDSGEYELSV 915

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
            +        +  + V EK          P   +  + V  T+  +     K  G   I  
Sbjct: 916  QIENMKDTATIRIRVVEK--------AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMG 967

Query: 4546 YWL-KNGKKVQP--DIRNKILEEDGTYTLLIL--EAYPQDSGKYECVAINSAGEARCDAE 4600
            Y++ K  KK     ++  +      T + LI+  E Y +   +  C   +S G ++  A 
Sbjct: 968  YFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1027

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             ++    T    + +       P+ + PL D++V  G +   +C + G P P V W K  
Sbjct: 1028 -ILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNK 1086

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
              I+    F ++      TL I    P D G Y C A N  G      KL+V  P
Sbjct: 1087 MEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1141



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 34/94 (36%), Positives = 51/94 (54%), Gaps = 2/94 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F  P+ D  V    +A     +   G PK +V W++N + I    +    +  G + 
Sbjct: 1048 APKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1105

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            LN++  +P D+GTYTCRA+NELGEA+    L V+
Sbjct: 1106 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1139



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 1/93 (1%)

Query: 390  LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
            +AP+F+    DR V  G     +C V G P P+V W  N  +IR+D    ++ N  G   
Sbjct: 1047 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF-LITNYQGVLT 1105

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            L I   +  D+G  TC A N+ GE   +C+L V
Sbjct: 1106 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 30/95 (31%), Positives = 51/95 (53%), Gaps = 3/95 (3%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP+F+T L     ++ G SA   C +  +P P  +V W  N   ++   ++  +N  G  
Sbjct: 1048 APKFLTPLIDRVVVA-GYSAALNCAVRGHPKP--KVVWMKNKMEIREDPKFLITNYQGVL 1104

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             L+I      D+G YTC+A+N LG+A++  +L V+
Sbjct: 1105 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1139



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 5/106 (4%)

Query: 2098 KPIEEEQPGQR--PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            KP E ++   R  P FLT L     +  G  A   C V     P   + W  N  +IR  
Sbjct: 1036 KPFEYKEHDFRMAPKFLTPLID-RVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIRED 1092

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             ++  T+  G + L+I      D+GTY C+A N+LGEA+  C L+V
Sbjct: 1093 PKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138



 Score = 52.4 bits (120), Expect = 4e-05
 Identities = 24/53 (45%), Positives = 32/53 (60%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAV 1662
            KV W  N   ++   +F  TN  G + L+I    P D+GTYTCRA+N LGEA+
Sbjct: 1079 KVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEAL 1131



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 29/90 (32%), Positives = 39/90 (43%)

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            +APKF+       V  G    LN    G P P++ W K+ + I  +P+  I    G  TL
Sbjct: 1047 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1106

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +I R    DA  Y C A N  G      +L
Sbjct: 1107 NIRRPSPFDAGTYTCRAVNELGEALAECKL 1136



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+F   L +   V G +  L C ++  G    +V W  N   I+   +F        + 
Sbjct: 1048 APKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1105

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L++    P D+G YTC+A N+LGEA+  C L V
Sbjct: 1106 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 29/88 (32%), Positives = 38/88 (43%)

Query: 4724 LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNT 4783
            LTPL D VV  G  A     +    KP + W++    I E P F + +      L I   
Sbjct: 1052 LTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRP 1111

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               D GT+TCRA    G+     KL V+
Sbjct: 1112 SPFDAGTYTCRAVNELGEALAECKLEVR 1139



 Score = 49.2 bits (112), Expect = 4e-04
 Identities = 36/107 (33%), Positives = 50/107 (46%), Gaps = 5/107 (4%)

Query: 2354 RELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQ-EGQTAHFDCRLIPVGDPTLKVEW 2412
            R L++   FK  E  E   R  P F  PL  ID +   G +A  +C +   G P  KV W
Sbjct: 1027 RILKTGITFKPFEYKEHDFRMAPKFLTPL--IDRVVVAGYSAALNCAVR--GHPKPKVVW 1082

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             +N+  I +  +   T+  G +++ I      D G Y CRA N LGE
Sbjct: 1083 MKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGE 1129



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 5/106 (4%)

Query: 2630 PEMFVDTGVQQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
            P  + +   + AP F T L   D++V  G    L   V  R  P  K+ W KN + +   
Sbjct: 1037 PFEYKEHDFRMAPKFLTPL--IDRVVVAGYSAALNCAV--RGHPKPKVVWMKNKMEIRED 1092

Query: 2689 ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +   T   G++TL+I      D+G YTC+A N LGEA++   +++
Sbjct: 1093 PKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+F T   D ++    SA   C +        +V W  N   +    +    N  G + L
Sbjct: 1049 PKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1106

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             I      DAG YTC+A N  GEA   CKL+V+
Sbjct: 1107 NIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1139



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 2/77 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G +A     +RG+P P V W + K  + E  K+ +  N Q G ++L I++  P D G YT
Sbjct: 1063 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT-NYQ-GVLTLNIRRPSPFDAGTYT 1120

Query: 146  CTARNQYGEAICSVYIQ 162
            C A N+ GEA+    ++
Sbjct: 1121 CRAVNELGEALAECKLE 1137



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+F+ PL     + G        +   G P  K+ W+KN   I    +F      G ++L
Sbjct: 1049 PKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1106

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++   +  D+G YTCRAV+  G A  +  L V
Sbjct: 1107 NIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 763  EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822
            E      P+F+ PL D   +  G +A     +     P  +V W K+   I    +    
Sbjct: 1042 EHDFRMAPKFLTPLIDR-VVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLIT 1098

Query: 823  FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               G ++LNI      DAG+YT RAVN+LGEA++   + V
Sbjct: 1099 NYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 6/84 (7%)

Query: 265 PPKIAQKPRNSKL----QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
           PPKI + PR+ +     + G      V   G PRP+V W K G  L  S  H + T+   
Sbjct: 838 PPKI-RLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH-VRTSDFD 895

Query: 321 TTLRVRNTQKSDSGHYTLLAENPN 344
           T   VR   +SDSG Y L  +  N
Sbjct: 896 TVFFVRQAARSDSGEYELSVQIEN 919



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PKF+T +    V         C V  +  PK ++ W +N   +    ++      G ++L
Sbjct: 1049 PKFLTPLIDRVVVAGYSAALNCAV--RGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1106

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            +I      D+G Y CRAVN+ GE   +  +  +
Sbjct: 1107 NIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1139



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F  P+ +  V  G+   L   +     P  +V W  N   +++  +F  T   G + L
Sbjct: 1049 PKFLTPLIDRVVVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTL 1106

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +I      D GTY C+A N +GEA+    ++V
Sbjct: 1107 NIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+F TP+ D++ +  G  A     +   G    +V W+K+   +    +       G + 
Sbjct: 1049 PKFLTPLIDRVVVA-GYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1105

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I+  +  DAG YTCRA N +G+A     L +
Sbjct: 1106 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 4103 EESKARCPPVFVS-LPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT- 4160
            +E   R  P F++ L D V V  G  A   C V GHPKP+V+W+ N   I    ++ +T 
Sbjct: 1041 KEHDFRMAPKFLTPLIDRVVVA-GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITN 1099

Query: 4161 YDGMYHFDIPKTRQYDTG 4178
            Y G+   +I +   +D G
Sbjct: 1100 YQGVLTLNIRRPSPFDAG 1117



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 3/98 (3%)

Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223
            +P    E   +  P F+ PL +   V+ G +  L C +   G P  +V W  N   +   
Sbjct: 1036 KPFEYKEHDFRMAPKFLTPLIDRVVVA-GYSAALNCAVR--GHPKPKVVWMKNKMEIRED 1092

Query: 1224 SRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261
             +F      G + L+I   +  D G YT RAVN LG A
Sbjct: 1093 PKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1130



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 3/66 (4%)

Query: 1719 DIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPE 1778
            D+ V  ++ A F+     V D K+  +W +NGV +  S R+T  H   +  L +  V PE
Sbjct: 447  DLTVKASEQAVFKCE---VSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPE 503

Query: 1779 DSGTYT 1784
            D G YT
Sbjct: 504  DEGDYT 509



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 3/108 (2%)

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTI 1489
            +K  +  +    + P+F+T P     V+ G      C +        KV W KN   +  
Sbjct: 1035 FKPFEYKEHDFRMAPKFLT-PLIDRVVVAGYSAALNCAVRG--HPKPKVVWMKNKMEIRE 1091

Query: 1490 GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
              +F   +  G + L+I      D+G YTCRAVN +G     C+L  R
Sbjct: 1092 DPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1139



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/79 (30%), Positives = 32/79 (40%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
            G  A     + G+P+P+V W KN   +    K  I       TL +R     D+G YT  
Sbjct: 1063 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCR 1122

Query: 340  AENPNGCIVTSGYLAVESP 358
            A N  G  +    L V  P
Sbjct: 1123 AVNELGEALAECKLEVRVP 1141



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 7/114 (6%)

Query: 3028 LEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASL--IPTGDQSMVIEWF 3085
            L+  +  +P +  + D    P+F T   D V      +A Y A+L     G     + W 
Sbjct: 1029 LKTGITFKPFEYKEHDFRMAPKFLTPLIDRV-----VVAGYSAALNCAVRGHPKPKVVWM 1083

Query: 3086 YNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
             N   I    +       G++ L I      D+GTY+CRA N+ G+A    KLE
Sbjct: 1084 KNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLE 1137



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 3/91 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+F   + D + V  G     +C V   G P  ++ W  N        +    N  G + 
Sbjct: 1049 PKFLTPLIDRV-VVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1105

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L+I      DAG YTCRA N+ G A    K+
Sbjct: 1106 LNIRRPSPFDAGTYTCRAVNELGEALAECKL 1136



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 3/85 (3%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P+++ P+  +  +V G    L   V  +  P  K+ W  N   + +  +F +T+  G +T
Sbjct: 1049 PKFLTPLI-DRVVVAGYSAALNCAV--RGHPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1105

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEA 2995
            L++      D+G YTC+A N+ GEA
Sbjct: 1106 LNIRRPSPFDAGTYTCRAVNELGEA 1130



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P+F+T L     V  G +A   C V     P  ++ +  N   ++   +F IT   G ++
Sbjct: 1049 PKFLTPLIDRV-VVAGYSAALNCAVRG--HPKPKVVWMKNKMEIREDPKFLITNYQGVLT 1105

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
            L+I+   P DAG Y+ +A+N LG   +   + V
Sbjct: 1106 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 19/55 (34%), Positives = 29/55 (52%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  +  W  N +E++   +F  T+  G +TL+I      DAG Y C+A+N  G
Sbjct: 1074 GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1128



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 21/64 (32%), Positives = 30/64 (46%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P  KV W  N   ++   +F      G + L I    P D+G Y CRA N  GEA+    
Sbjct: 1076 PKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECK 1135

Query: 3510 MKVQ 3513
            ++V+
Sbjct: 1136 LEVR 1139



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 2/69 (2%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G SA   C V     P  K+ W  N   +R   +    +  G + L+I      D+G Y 
Sbjct: 1063 GYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYT 1120

Query: 3224 CRAYNKYGE 3232
            CRA N+ GE
Sbjct: 1121 CRAVNELGE 1129



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G   + +  + G P PV +W  K   +    +   R  ++    S +I+     DEG YT
Sbjct: 560 GNKLRLDVSITGEPPPVATWL-KGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYT 618

Query: 146 CTARNQYGEAICSVYIQ 162
               N  GE + S+++Q
Sbjct: 619 IKVTNPVGEDVASIFLQ 635



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 8/99 (8%)

Query: 751 EDYSKYQ---HQESIEEQTSQRPQFIRPLQDLGEL--QEGRNAHFEAQLTPVSDPTMRVE 805
           ED  +YQ   +    E +     + +  LQD+ +L  +    A F+ +   VSD  +  +
Sbjct: 414 EDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCE---VSDEKVTGK 470

Query: 806 WYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
           WYK+G  +  S RIT      +  L I  +R ED G YT
Sbjct: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 20/49 (40%), Positives = 26/49 (53%)

Query: 1071 SDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVV 1119
            SD  +T +WY NG ++  + RI   H   +  L I  VR ED G YT V
Sbjct: 463  SDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFV 511



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH-NHTTLRVRNTQKSDSGHYTL 338
           G   +  V ++G P P  TW K  +    +     I    + ++  + + Q+ D G YT+
Sbjct: 560 GNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 619

Query: 339 LAENPNGCIVTSGYLAV 355
              NP G  V S +L V
Sbjct: 620 KVTNPVGEDVASIFLQV 636



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            ++  + A F C    V D  +  +W++N   +  S RIT +H   +  + I  VR EDEG
Sbjct: 450  VKASEQAVFKCE---VSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEG 506

Query: 2448 VY 2449
             Y
Sbjct: 507  DY 508



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 3/88 (3%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D +  P+F+T +  +  +V   +    C +   G P  KV W  N   +    +F     
Sbjct: 1044 DFRMAPKFLTPLIDRV-VVAGYSAALNCAVR--GHPKPKVVWMKNKMEIREDPKFLITNY 1100

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             G + +N     P D+G Y CRA N  G
Sbjct: 1101 QGVLTLNIRRPSPFDAGTYTCRAVNELG 1128



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++ L + V   G +    C V     P  K+ W  N   +    ++  T+    ++L+I
Sbjct: 1051 FLTPLIDRVVVAGYSAALNCAVRGHPKP--KVVWMKNKMEIREDPKFLITNYQGVLTLNI 1108

Query: 2836 THTYEEDSGIYTCKATNSKGSA 2857
                  D+G YTC+A N  G A
Sbjct: 1109 RRPSPFDAGTYTCRAVNELGEA 1130


>AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.
          Length = 1598

 Score = 90.2 bits (214), Expect = 2e-16
 Identities = 79/288 (27%), Positives = 123/288 (42%), Gaps = 29/288 (10%)

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECV 4587
            ++V +  +  G  P  + W K+   V+ +   +  +  DG   L I    P D+G ++C 
Sbjct: 1    KVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG--LQISGLVPDDTGMFQCF 58

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N+AGE +      V+  A               P I     D  V +G ++  +C+  
Sbjct: 59   ARNAAGEVQTSTYLAVTSIA---------------PNITRGPLDSTVIDGMSVVLACETS 103

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSR--TADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            G P P + W KG++++  S   Q+ R    +  +L IS     D G Y C+A NS G   
Sbjct: 104  GAPRPAITWQKGERIL-ASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE 162

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ--WLREGALIPE 4763
             +A L V    +        P +D  V +G  A     +T   + TI+  W ++GA +  
Sbjct: 163  ASADLVVWARTRITK-----PPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATL-G 216

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            T     I    N  L I  T+  D GT+TCR  +A G    SA L V+
Sbjct: 217  TESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVR 264



 Score = 83.0 bits (196), Expect = 2e-14
 Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 12/181 (6%)

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
            + ++  C+  G P P++ WYK   +++  K  +  R  ++  L+IS   P+D G ++C A
Sbjct: 1    KVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRF-RQRNDGGLQISGLVPDDTGMFQCFA 59

Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
             N+AG V  +  L VT    A N+    PL D  V +G       + +   +P I W + 
Sbjct: 60   RNAAGEVQTSTYLAVTSI--APNITR-GPL-DSTVIDGMSVVLACETSGAPRPAITWQKG 115

Query: 4758 GALIP----ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              ++     + P F  +  G+   LLI  T+  D GT+TC AT + G  E SA LVV ++
Sbjct: 116  ERILASGSVQLPRFTPLESGS---LLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR 172

Query: 4814 T 4814
            T
Sbjct: 173  T 173



 Score = 64.5 bits (150), Expect = 9e-09
 Identities = 50/174 (28%), Positives = 72/174 (41%), Gaps = 9/174 (5%)

Query: 407 KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV 466
           K+    C+  G P P +TW+ +   +  +   +      G   L I+ +   D+G+  C 
Sbjct: 1   KVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG--LQISGLVPDDTGMFQCF 58

Query: 467 ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
           ARN +GE      L V      +AP          V +G  VVL     G P P ITWQK
Sbjct: 59  ARNAAGEVQTSTYLAVTS----IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK 114

Query: 527 DGVPIIPNPELRI--HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            G  I+ +  +++   T   + +L I     SDA  Y C A N  G     A L
Sbjct: 115 -GERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADL 167



 Score = 58.8 bits (136), Expect = 4e-07
 Identities = 47/203 (23%), Positives = 78/203 (38%), Gaps = 8/203 (3%)

Query: 378 ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
           E +    ++  ++AP   +   D  V +G      C  +G P P +TW   +R +     
Sbjct: 65  EVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSV 124

Query: 438 HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
                    + +L+I+   +SD+G  TC+A N  G       L V  + ++  P      
Sbjct: 125 QLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPP----- 179

Query: 498 STLNVREGEPVVLNARAVGTP--TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
              +V +G    +       P  T R  W+KDG  +      RI  D   S L I +  +
Sbjct: 180 QDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGS-LHISQTWS 238

Query: 556 SDAAWYQCTAQNVAGSTATRARL 578
            D   Y C   +  G+ +  A L
Sbjct: 239 GDIGTYTCRVISAGGNDSRSAHL 261



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 66/293 (22%), Positives = 114/293 (38%), Gaps = 30/293 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I WY++   ++     +    +   + I   V  +D+ +F   A N  G  + S
Sbjct: 11   GVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLV-PDDTGMFQCFARNAAGEVQTS 69

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV- 4554
              L V           + P+ T    +  V  G  V L  + +G     + W K G+++ 
Sbjct: 70   TYLAVTS---------IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERIL 119

Query: 4555 -QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
                ++        + +LLI   +  D+G Y C+A NS G     A+ VV          
Sbjct: 120  ASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVW--------- 170

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKYFQMS 4672
                   A   I +P +D+ V +G      C +   P  T+++ ++ D     ++     
Sbjct: 171  -------ARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 223

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            R     +L IS+ +  D G Y C   ++ G  + +A L+V Q   A   P  T
Sbjct: 224  RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVAT 276



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 36/112 (32%), Positives = 51/112 (45%), Gaps = 3/112 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI--ITTHNHTTL 323
           P I + P +S + +G       + SG PRP +TW K G+R++ S   ++   T     +L
Sbjct: 79  PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK-GERILASGSVQLPRFTPLESGSL 137

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQ 375
            +  T  SD+G YT LA N  G    S  L V + T      Q    I  TQ
Sbjct: 138 LISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQ 189



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 3/66 (4%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           +G P P ++W  K A +VE  K + R+  Q  D  L I  + P D G + C ARN  GE 
Sbjct: 10  KGVPPPSITWY-KDAAVVEVEKLT-RFR-QRNDGGLQISGLVPDDTGMFQCFARNAAGEV 66

Query: 156 ICSVYI 161
             S Y+
Sbjct: 67  QTSTYL 72



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 48/174 (27%), Positives = 63/174 (36%), Gaps = 5/174 (2%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            +G V T T  A +   P  T  P D  + +  S    C        +  + W    + L 
Sbjct: 63   AGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPA--ITWQKGERILA 120

Query: 3602 TGS-RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
            +GS ++          L I   +  DAG YTC ATN  G    S  L V  R  I   PQ
Sbjct: 121  SGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQ 180

Query: 3661 LPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVH 3714
              S  K GT++      T   R  I    EK      T E    I +   G +H
Sbjct: 181  DQSVIK-GTQASMVCGVTHDPRVTIRYIWEKDGATLGT-ESHPRIRLDRNGSLH 232



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 1/70 (1%)

Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
           Q  G P P +TW+K+   ++   K       N   L++      D+G +   A N  G +
Sbjct: 8   QAKGVPPPSITWYKDAA-VVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEV 66

Query: 348 VTSGYLAVES 357
            TS YLAV S
Sbjct: 67  QTSTYLAVTS 76



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 36/126 (28%), Positives = 53/126 (42%), Gaps = 7/126 (5%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I  T  +D+GTY+C ATN  G  E S  L    +++  KP      Q+   +K G  A
Sbjct: 137  LLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPP-----QDQSVIK-GTQA 190

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C V       ++  W  +G  +   +  +   D     L I+ T + D G Y CR  
Sbjct: 191  SMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRN-GSLHISQTWSGDIGTYTCRVI 249

Query: 3228 NKYGED 3233
            +  G D
Sbjct: 250  SAGGND 255



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 35/131 (26%), Positives = 52/131 (39%), Gaps = 4/131 (3%)

Query: 1408 LILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECK 1467
            L++   H S       L   SR       D  V  + R +T+P   ++VI+G      C 
Sbjct: 137  LLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTR-ITKPPQDQSVIKGTQASMVCG 195

Query: 1468 LEPVTDSNLKVEWFKNGQPVTIGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            +       ++  W K+G   T+G    P I      +L I    + D G YTCR ++  G
Sbjct: 196  VTHDPRVTIRYIWEKDG--ATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGG 253

Query: 1527 TDEVSCRLTCR 1537
             D  S  L  R
Sbjct: 254  NDSRSAHLRVR 264



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 5/91 (5%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI---SLDMLSLNIQDSGEYTCRAVSAT 717
           E  G P   I W K G+ I AS     + RF  +   SL +   +I D+G YTC A ++ 
Sbjct: 101 ETSGAPRPAITWQK-GERILASGS-VQLPRFTPLESGSLLISPTHISDAGTYTCLATNSR 158

Query: 718 GVAETKAVLHVTPRATIERTSQHPETLQYIQ 748
           GV E  A L V  R  I +  Q    ++  Q
Sbjct: 159 GVDEASADLVVWARTRITKPPQDQSVIKGTQ 189



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 9/114 (7%)

Query: 1447 VTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH----RFRPIHDFGYV 1502
            +TR      VI+G  V   C+          + W K  + +  G     RF P+      
Sbjct: 81   ITRGPLDSTVIDGMSVVLACETSGAPRP--AITWQKGERILASGSVQLPRFTPLESG--- 135

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQ 1556
            +L I      D+G YTC A N  G DE S  L   + T I +  Q+++ ++  Q
Sbjct: 136  SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQ 189



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 1/69 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W ++   +E   +LT         L +  + P+D+G + C A N  GE  TS
Sbjct: 11   GVPPPSITWYKDAAVVEVE-KLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS 69

Query: 1798 STLFVQSKA 1806
            + L V S A
Sbjct: 70   TYLAVTSIA 78



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 3/78 (3%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGT-RYKSTHDFSYVSLDITHTYEEDSGI 2845
            +G ++   C  E S  P   I W    + L SG+ +          SL I+ T+  D+G 
Sbjct: 92   DGMSVVLAC--ETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGT 149

Query: 2846 YTCKATNSKGSATTSGSL 2863
            YTC ATNS+G    S  L
Sbjct: 150  YTCLATNSRGVDEASADL 167



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 5/57 (8%)

Query: 2536 GDPSLRFEWYING--VELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P     WY +   VE++  +RFR  +D G   L I+ +V +D G++ C A N AG
Sbjct: 11   GVPPPSITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFARNAAG 64



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD   VE   ++T F       L I  +   D G + C A NA G+  TS  L + 
Sbjct: 17   ITWYKDAAVVEVE-KLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVT 75

Query: 1003 T 1003
            +
Sbjct: 76   S 76


>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhesion
            molecule like-protein 1b protein.
          Length = 1842

 Score = 89.8 bits (213), Expect = 2e-16
 Identities = 90/378 (23%), Positives = 151/378 (39%), Gaps = 47/378 (12%)

Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAV 4480
            F ++  +      G P+P I+W ++  P+     +      TK I  L I  +  EDS  
Sbjct: 27   FVNDSLQLPCTAPGYPIPAIRWLKDGRPLPADSRW------TKRITGLTISDLRTEDSGT 80

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
            +     N  G+A+ +  L+V          I P   TLT + +    G  V L   +TG+
Sbjct: 81   YICEVTNTFGSAEATGILMV----------IDPLHVTLTPKKLKTGIGSTVILSCALTGS 130

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
                + W +N + V PD    I       TLLI  A    SG Y+C A   A  A+  A 
Sbjct: 131  PEFTIRWYRNTELVLPDEAISIRGLSNE-TLLITSAQKSHSGAYQCFATRKAQTAQDFA- 188

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
             +++L              +  P I+    +K+V  G+     C   G P PTV W   D
Sbjct: 189  -IIALE-------------DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 234

Query: 4661 K-LIKPSKYFQMSRTADEYT----LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            + +++   +     T  + T    + ++     D G Y+C A N  G     A++ V  P
Sbjct: 235  EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 294

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
                  P++  +R+I    G+      ++      +I+W ++  L+P+    Q++ E N 
Sbjct: 295  ------PSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDN-HRQVVFE-NG 346

Query: 4776 AVLLIGNTYEEDTGTFTC 4793
             + L       D G + C
Sbjct: 347  TLKLTDVQKGMDEGEYLC 364



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 53/178 (29%), Positives = 79/178 (44%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C +TG P   + W+ N   +  D    I +    N  L+IT+   S SG   C
Sbjct: 118 GSTVILSCALTGSPEFTIRWYRNTELVLPD--EAISIRGLSNETLLITSAQKSHSGAYQC 175

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
            A  K+ +TA    +  +E      P+ V  FS   V  GE   L   A G P P +TW 
Sbjct: 176 FATRKA-QTAQDFAIIALEDG---TPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWA 231

Query: 526 KDGVPIIPNPELRIH----TDGGA-STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+ +   R +    +DG   S +++   +  D   Y+CTA+N+ GS   +AR+
Sbjct: 232 LDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARI 289



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 71/177 (40%), Gaps = 12/177 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHAL 450
           P+ V    ++ V  G+     C   G P P VTW ++D  I  D +H+      S    +
Sbjct: 197 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 256

Query: 451 MITNVT---LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
              NVT   + D GV  C ARN  G   +Q R+N      V  P  +     +    G  
Sbjct: 257 SHMNVTGPQIRDGGVYRCTARNLVGSAEYQARIN------VRGPPSIRAMRNITAVAGRD 310

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            ++N R +G P   I W KD + +  N    +  +G     D+   K  D   Y C+
Sbjct: 311 TLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDV--QKGMDEGEYLCS 365



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 91/426 (21%), Positives = 161/426 (37%), Gaps = 37/426 (8%)

Query: 4393 KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK 4452
            KAQT +      ++   P I +   +   V   EQ        G P P + W  ++ PI 
Sbjct: 180  KAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQFSLMCAAKGAPPPTVTWALDDEPIV 238

Query: 4453 NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
                 + + ++      I  + V    +        GG  +C+A  +V     Q R  + 
Sbjct: 239  RDGSHRTNQYTMSDGTTISHMNVTGPQI------RDGGVYRCTARNLVGSAEYQARINVR 292

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
             P      +N+   +G+   ++ +V G     + W K+   + PD   +++ E+GT  L 
Sbjct: 293  GPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGTLKLT 351

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
             ++    D G+Y C               V+  P           A   PP +I+P +  
Sbjct: 352  DVQK-GMDEGEYLC--------------SVLIQPQLSISQSVHV-AVKVPP-LIQPFEFP 394

Query: 4633 IVAEGQAIEFSCKIVGKPLPT-VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              + GQ +   C +    +P  + W K  ++I       +       +L+IS    +  G
Sbjct: 395  PASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNG 454

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            +  C+A N+A  V+   +L V  P +      + P     +Y G+       +     P 
Sbjct: 455  NDTCIASNAAATVSRERQLIVRVPPRF----VVQPNNQDGIY-GKAGVLNCSVDGYPPPK 509

Query: 4752 IQWLR-EGALIPE----TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG-QVETS 4805
            + W   +G+  P+     P    I    N+ LLI +  EED G + C+A+   G  +  S
Sbjct: 510  VMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKS 569

Query: 4806 AKLVVK 4811
              L VK
Sbjct: 570  MFLTVK 575



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 44/177 (24%), Positives = 71/177 (40%), Gaps = 12/177 (6%)

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            +++  C   G P+P ++W K  + +     +    T     L IS+   ED G Y C   
Sbjct: 31   SLQLPCTAPGYPIPAIRWLKDGRPLPADSRWTKRITG----LTISDLRTEDSGTYICEVT 86

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
            N+ G       L V  P        LTP + +    G        +T   + TI+W R  
Sbjct: 87   NTFGSAEATGILMVIDPLHV----TLTP-KKLKTGIGSTVILSCALTGSPEFTIRWYRNT 141

Query: 4759 ALIPETPDFQMIHEG-NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             L+   PD  +   G +N  LLI +  +  +G + C AT  A   +  A + ++  T
Sbjct: 142  ELV--LPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGT 196



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 50/190 (26%), Positives = 79/190 (41%), Gaps = 16/190 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T  +CRV G PY  + W+  D  +  D NH+ +V E+G   L 
Sbjct: 294 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWY-KDALLLPD-NHRQVVFENGT--LK 349

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +T+V    D G   C           Q +L++ +   V    P  ++ F       G+ +
Sbjct: 350 LTDVQKGMDEGEYLC-------SVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLL 402

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +         P RITW+KDG  II    + I +    S+L I            C A N
Sbjct: 403 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASN 462

Query: 568 VAGSTATRAR 577
            A +T +R R
Sbjct: 463 -AAATVSRER 471



 Score = 50.4 bits (115), Expect = 2e-04
 Identities = 61/273 (22%), Positives = 102/273 (37%), Gaps = 32/273 (11%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            + WLK+G+ +  D R           L I +   +DSG Y C   N+ G A      +V 
Sbjct: 46   IRWLKDGRPLPADSR----WTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 101

Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
             P                   + P K K    G  +  SC + G P  T++WY+  +L+ 
Sbjct: 102  DPLHVT---------------LTPKKLK-TGIGSTVILSCALTGSPEFTIRWYRNTELVL 145

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
            P +   +   ++E TL I+ A     G Y+C A   A      A + +      D  P +
Sbjct: 146  PDEAISIRGLSNE-TLLITSAQKSHSGAYQCFATRKAQTAQDFAIIAL-----EDGTPRI 199

Query: 4725 -TPLRDIVVYEGQPAQFKTQITSKIKPTIQW-LREGALIPE----TPDFQMIHEGNNAVL 4778
             +   + VV  G+             PT+ W L +  ++ +    T  + M      + +
Sbjct: 200  VSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHM 259

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
             +      D G + C A    G  E  A++ V+
Sbjct: 260  NVTGPQIRDGGVYRCTARNLVGSAEYQARINVR 292



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 67/291 (23%), Positives = 101/291 (34%), Gaps = 36/291 (12%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I W ++   I +     I +    S L I  V ++ +     +A N   T      L+V 
Sbjct: 417  ITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRERQLIVR 476

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK-----NGKKVQP 4556
                      VPP F +   N +   G+   L+  V G  P  V W       N ++  P
Sbjct: 477  ----------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHP 526

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
                  ++     +LLI     +D G Y C A N  G                D  K   
Sbjct: 527  VPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGT---------------DISKSMF 571

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS---KYFQMSR 4673
                 P  I       I  +G A E +C   G+    ++W KGD +I P    +Y   ++
Sbjct: 572  LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 631

Query: 4674 TADEYTLRISEAFPEDEGD---YKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
               +  +   +  P D GD   + C A NS G      +L V +P     L
Sbjct: 632  DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPEL 682



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 774 RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIM 833
           RP +D+G      N   +   T    P   + W KDGRP+ A SR T         L I 
Sbjct: 17  RP-EDVGTSLYFVNDSLQLPCTAPGYPIPAIRWLKDGRPLPADSRWTK----RITGLTIS 71

Query: 834 HLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            LR ED+G+Y     N  G A +T  + V
Sbjct: 72  DLRTEDSGTYICEVTNTFGSAEATGILMV 100



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 13/148 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W  +G+ + A  R  T    G+ + ++   +T DSGTY C  TN +G AE +  L  +
Sbjct: 46   IRWLKDGRPLPADSRW-TKRITGLTISDL---RTEDSGTYICEVTNTFGSAEATGILMVI 101

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            D      P   T     + LK G  +    +      P+  I WY N + +     I ++
Sbjct: 102  D------PLHVT--LTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI-SI 152

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229
                   L I   Q   SG Y C A  K
Sbjct: 153  RGLSNETLLITSAQKSHSGAYQCFATRK 180



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPIIPNPELR 538
            IE       K +    T+     + V L   +VG P P + W KD     +P+  +    
Sbjct: 1071 IEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRL 1130

Query: 539  IHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            IHT+G   TL +   KA D+ +Y CTA N  G
Sbjct: 1131 IHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1159



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 41/158 (25%), Positives = 61/158 (38%), Gaps = 13/158 (8%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C   G P P + W  + R +  D      +       L I+++   DSG   C   N  G
Sbjct: 36  CTAPGYPIPAIRWLKDGRPLPADSRWTKRIT-----GLTISDLRTEDSGTYICEVTNTFG 90

Query: 473 ETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
                  L VI+   V + PK       L    G  V+L+    G+P   I W ++   +
Sbjct: 91  SAEATGILMVIDPLHVTLTPK------KLKTGIGSTVILSCALTGSPEFTIRWYRNTELV 144

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           +P+  + I       TL I  A+ S +  YQC A   A
Sbjct: 145 LPDEAISIRGLSN-ETLLITSAQKSHSGAYQCFATRKA 181



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLKDGRP+ A SR T         LTI  +   D+G Y C   N  G A  +  L ++
Sbjct: 46   IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 101



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 53/246 (21%), Positives = 103/246 (41%), Gaps = 16/246 (6%)

Query: 338 LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
           LL +N    +  +G L +    +   + +    +    Q    + + ++ K   P  ++ 
Sbjct: 333 LLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKV--PPLIQP 390

Query: 398 CQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            +    + G++    C V+    P  +TW   D Q+    +   + ++    +L I++V+
Sbjct: 391 FEFPPASIGQLLYIPCVVSSGDMPIRITWR-KDGQVIISGSGVTIESKEFMSSLQISSVS 449

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
           L  +G  TC+A N +   + + +L V      V P+FV + +  +   G+  VLN    G
Sbjct: 450 LKHNGNDTCIASNAAATVSRERQLIVR-----VPPRFVVQPNNQDGIYGKAGVLNCSVDG 504

Query: 517 TPTPRITWQK---DGVPIIPNP---ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P P++ W+     G P   +P     RI     +S L I      D  +Y C A N  G
Sbjct: 505 YPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL-IRHVLEEDIGYYLCQASNGVG 563

Query: 571 STATRA 576
           +  +++
Sbjct: 564 TDISKS 569



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 49/189 (25%), Positives = 72/189 (38%), Gaps = 14/189 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI----LVNESGN 447
           P+FV    ++D   GK    +C V G P P+V W            H +     +    N
Sbjct: 479 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 538

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            +L+I +V   D G   C A N  G    +     ++    +        +T    +G  
Sbjct: 539 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVK----IPAMITSHPNTTIAIKGHA 594

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELR--IHT-DGG---ASTLDIPRAKASDAAWY 561
             LN  A G     I W+K    I P+  +R  I T D G    STL +  A   D+ ++
Sbjct: 595 KELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFF 654

Query: 562 QCTAQNVAG 570
            C A N  G
Sbjct: 655 SCHAINSYG 663



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 17/162 (10%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L+IR V  ED   +   A N  GT   S ++ +  K        +P   T        
Sbjct: 539  SSLLIRHVLEEDIGYYLCQASNGVGT-DISKSMFLTVK--------IPAMITSHPNTTIA 589

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD--IRNKILEED-GTYTLLILEAYPQDSG 4582
              G    L+    G +PI + W K    + PD  +R  I  +D G   +  L+  P D G
Sbjct: 590  IKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRG 649

Query: 4583 K---YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
                + C AINS GE R   +  V  P   D P+ + +   A
Sbjct: 650  DSVFFSCHAINSYGEDRGLIQLTVQEP--PDPPELEIREVKA 689



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 44/185 (23%), Positives = 82/185 (44%), Gaps = 20/185 (10%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            S GQ+  Y   ++ +GD  + I W  +G+ I +   +       M  L+I       +G 
Sbjct: 397  SIGQLL-YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGN 455

Query: 3121 YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
             +C A+N    A +S + + + +     PRF     N +G+  G++    C+V     P 
Sbjct: 456  DTCIASN--AAATVSRERQLIVR---VPPRFVVQPNNQDGIY-GKAGVLNCSVDGYPPP- 508

Query: 3181 MKIEWYH---NGQPMRH-----STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             K+ W H   +G P ++     + RI+ + +   +   I +    D G Y+C+A N  G 
Sbjct: 509  -KVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL---IRHVLEEDIGYYLCQASNGVGT 564

Query: 3233 DFTRA 3237
            D +++
Sbjct: 565  DISKS 569



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            + W  + +PL + SR+T+        L I     EDSGTY C   N  G A  +GI +V
Sbjct: 46   IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMV 100



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   I WLK+G+ + A SR+T         L +  L  +DSG Y C   +  G AE  
Sbjct: 40  GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 95

Query: 724 AVLHV 728
            +L V
Sbjct: 96  GILMV 100



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P   I W  + +PLP+ +R+          L I+    EDSG Y C+ TN+ GSA  +G 
Sbjct: 42   PIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGI 97

Query: 2863 L 2863
            L
Sbjct: 98   L 98



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 57/275 (20%), Positives = 98/275 (35%), Gaps = 17/275 (6%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVSLLIKQIGPG--DEGEYTCTARNQY 152
           +G P P V+W     P+V    + + +Y    G     +   GP   D G Y CTARN  
Sbjct: 221 KGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLV 280

Query: 153 GEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
           G A     I   G                    +  +  G   Y+ +  +    +     
Sbjct: 281 GSAEYQARINVRGPPSIRAMRNITAVAGR-DTLINCRVIGYPYYSIKWYKDALLL----- 334

Query: 213 TDHSSTDDFKVDTFEYRLLREVSFRESITK-RYVGESDVQISTEIDRSLG-PVSPPKIAQ 270
                 D+ +   FE   L+    ++ + +  Y+    +Q    I +S+   V  P + Q
Sbjct: 335 -----PDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQ 389

Query: 271 KPRNSKLQEGADAQFQVQLSGNPRP-RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQ 329
                    G        +S    P R+TW K+GQ +I+ +   I +    ++L++ +  
Sbjct: 390 PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVS 449

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
              +G+ T +A N    +     L V  P    VQ
Sbjct: 450 LKHNGNDTCIASNAAATVSRERQLIVRVPPRFVVQ 484



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 9/110 (8%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV  PP+F+ Q  +      +     C V+    PK  + W ++ K   +  +Y  V   
Sbjct: 474  IVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPK--VMW-KHAKGSGNPQQYHPVPLT 530

Query: 3885 GFV------SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            G +      SL I +V  ED G Y+C+A N  G D +K+     K+P +I
Sbjct: 531  GRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 580



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++G P+ A +R T         L +  +  EDSGTY C   N  G A  +
Sbjct: 40   GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEAT 95

Query: 1798 STLFV 1802
              L V
Sbjct: 96   GILMV 100



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            I W K+G  L   +R        +  L+I+ LR +DSG Y C+ TN  G A +T  + + 
Sbjct: 46   IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 101

Query: 2736 D 2736
            D
Sbjct: 102  D 102



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 4/135 (2%)

Query: 3800 PQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            PQ   G   +   R  +  A  +  I    P  I  +++ T          CRV     P
Sbjct: 264  PQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGY--P 321

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               I+WY++  LLP  HR + V++ G + L  +     D GEY+C  +       +++  
Sbjct: 322  YYSIKWYKDALLLPDNHR-QVVFENGTLKLTDVQ-KGMDEGEYLCSVLIQPQLSISQSVH 379

Query: 3920 SCKKLPDIILQNQVP 3934
               K+P +I   + P
Sbjct: 380  VAVKVPPLIQPFEFP 394



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 3/105 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P +   A  G  ++    +   GD  ++I W K+GQ I + S  T   +    SL
Sbjct: 385 PPLIQPFEFPPASIGQLLYIPCVVSS-GDMPIRITWRKDGQVIISGSGVTIESKEFMSSL 443

Query: 697 DMLSLNIQDSGEYTCRA--VSATGVAETKAVLHVTPRATIERTSQ 739
            + S++++ +G  TC A   +AT   E + ++ V PR  ++  +Q
Sbjct: 444 QISSVSLKHNGNDTCIASNAAATVSRERQLIVRVPPRFVVQPNNQ 488



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/174 (23%), Positives = 64/174 (36%), Gaps = 13/174 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W+ N + +     I ++       L I   + + SG Y C AT K   A+ 
Sbjct: 128  TGSPEFTIRWYRNTELVLPDEAI-SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 186

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-- 3192
               +   D +      F+  + N      G+     C       P   + W  + +P+  
Sbjct: 187  FAIIALEDGTPRIVSSFSEKVVN-----PGEQFSLMCAAKGAPPPT--VTWALDDEPIVR 239

Query: 3193 --RHSTRIKTVSDFGFVV-LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
               H T   T+SD   +  +++   Q  D G Y C A N  G    +A IN  G
Sbjct: 240  DGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG 293



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 4436 GEPLPLIKWYREN----FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
            G+P P +KW +++     P+       IHT  T   L++R V  EDS  +   A N GG 
Sbjct: 1104 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT---LLLRAVKAEDSGYYTCTATNTGGF 1160

Query: 4492 AKCSANLVVEEKRRQGR 4508
                 NL+V+    Q R
Sbjct: 1161 DTIIVNLLVQVPPDQPR 1177



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 21/81 (25%), Positives = 37/81 (45%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD  +R+ W KDG+ + + S +T        +L I SV++   G+ TC A NA    +  
Sbjct: 411  GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRE 470

Query: 997  ANLTIVTKKDIIAESQHPGGL 1017
              L +      + +  +  G+
Sbjct: 471  RQLIVRVPPRFVVQPNNQDGI 491



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 5/88 (5%)

Query: 3454 VEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            + W  +G+ L A SR+          L IS    EDSG Y+C   N +G A  T  + V 
Sbjct: 46   IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 101

Query: 3514 GKRNIIL-ESQLPKGMEGTIDKIAALEG 3540
               ++ L   +L  G+  T+    AL G
Sbjct: 102  DPLHVTLTPKKLKTGIGSTVILSCALTG 129



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/124 (22%), Positives = 47/124 (37%), Gaps = 1/124 (0%)

Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
           S E    L  + P  +   P+  K   G+       L+G+P   + W++N + ++     
Sbjct: 91  SAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI 150

Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYIT 372
            I    N T L + + QKS SG Y   A            +A+E  T   V     + + 
Sbjct: 151 SIRGLSNETLL-ITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVN 209

Query: 373 DTQQ 376
             +Q
Sbjct: 210 PGEQ 213



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/104 (32%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG--DKLIKPSKY-FQMSRT 4674
            A  AP +II           + +   C  VG P P V+W K   D  I  S    ++  T
Sbjct: 1074 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHT 1133

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQ 4717
                 LR  +A  ED G Y C A N+ G  T+   L V   PDQ
Sbjct: 1134 NGTLLLRAVKA--EDSGYYTCTATNTGGFDTIIVNLLVQVPPDQ 1175



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 282  DAQFQVQLSGNPRPRVTWFKNGQRL---INSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            D +      G+P P V W K+ +     ++ + H +I  H + TL +R  +  DSG+YT 
Sbjct: 1095 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLI--HTNGTLLLRAVKAEDSGYYTC 1152

Query: 339  LAENPNGCIVTSGYLAVESPTE 360
             A N  G       L V+ P +
Sbjct: 1153 TATNTGGFDTIIVNLLVQVPPD 1174



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 9/90 (10%)

Query: 1471 VTDSNLKVEWFKNGQ----PVTI-GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525
            V D    V+W K+ +    PV++ GHR   IH  G + L  +   AEDSG YTC A N  
Sbjct: 1103 VGDPAPAVKWTKDSEDSAIPVSMDGHRL--IHTNGTLLLRAVK--AEDSGYYTCTATNTG 1158

Query: 1526 GTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555
            G D +   L  +   D  R T ++     I
Sbjct: 1159 GFDTIIVNLLVQVPPDQPRLTVSKTSASSI 1188



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-- 3870
            RG  S+    EP    P K I+   + T    + VR  C      DP   ++W ++ +  
Sbjct: 1062 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCN--SVGDPAPAVKWTKDSEDS 1119

Query: 3871 LLP-SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             +P S   +R ++  G  +L +  V AEDSG Y C A N  G D     +  +  PD
Sbjct: 1120 AIPVSMDGHRLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPD 1174



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 1997 LEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
            L+   T    P   + W  +GRP+    R+ T    G    D+     ED+GTY+C+ TN
Sbjct: 32   LQLPCTAPGYPIPAIRWLKDGRPLPADSRW-TKRITGLTISDLR---TEDSGTYICEVTN 87

Query: 2057 AVGEAVTTSSVKV 2069
              G A  T  + V
Sbjct: 88   TFGSAEATGILMV 100



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 4/60 (6%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G P   I W  +GRP    SR  T    G   L I  +   D+G Y C  TN +GSA  T
Sbjct: 40   GYPIPAIRWLKDGRPLPADSR-WTKRITG---LTISDLRTEDSGTYICEVTNTFGSAEAT 95



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            G P   + W ++ + +   SR TK        +TIS +R ED G Y+C  +N  G
Sbjct: 40   GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFG 90



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
            G P   + W  +G+PL   +R+T         +    +  EDSG Y+C  TN +G  E  
Sbjct: 40   GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 95

Query: 4061 AVI 4063
             ++
Sbjct: 96   GIL 98



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W  +G+ + A  R+ T    G    D+     EDSGTY+C+ TN  G A  T  
Sbjct: 42   PIPAIRWLKDGRPLPADSRW-TKRITGLTISDLR---TEDSGTYICEVTNTFGSAEATGI 97

Query: 2199 LKVAGHRNIIL 2209
            L V    ++ L
Sbjct: 98   LMVIDPLHVTL 108



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 4/54 (7%)

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            + W K+G+P+    R+          L I DL  EDSG Y C   N  G+ E +
Sbjct: 46   IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 95



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLL----HK-NRFTPIYDFGYVAMNFGWVYPEDSGEY 4046
            +F    A  G P   V W  + +P++    H+ N++T         MN       D G Y
Sbjct: 213  QFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVY 272

Query: 4047 LCRATNLYGMDETKAVIKTTGKPGI 4071
             C A NL G  E +A I   G P I
Sbjct: 273  RCTARNLVGSAEYQARINVRGPPSI 297



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 1861 SAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920
            S    C    YP P +R  W  +G+ L +  R+ T    G    D+ T   EDSG Y C+
Sbjct: 31   SLQLPCTAPGYPIPAIR--WLKDGRPLPADSRW-TKRITGLTISDLRT---EDSGTYICE 84

Query: 1921 AINNLGQA 1928
              N  G A
Sbjct: 85   VTNTFGSA 92



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 4/60 (6%)

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            + W  +G+P+    R+          L +  +  EDSG Y C+ TN  G A  +  L VI
Sbjct: 46   IRWLKDGRPLPADSRWTKRI----TGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 101



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 4/49 (8%)

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            I W ++G+ LP+  R+          L I  +  EDSG YIC   N FG
Sbjct: 46   IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFG 90



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PPRFV Q  +Q  +   +     C +   G P  KV W  + K   +  ++ P+   G +
Sbjct: 478  PPRFVVQPNNQDGIYG-KAGVLNCSVD--GYPPPKVMWK-HAKGSGNPQQYHPVPLTGRI 533

Query: 4032 ------AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                  ++    V  ED G YLC+A+N  G D +K++  T   P ++
Sbjct: 534  QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 580



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 18/122 (14%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMP-MKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
            R N  E  +      A  ++I+     T P MKD+R+  N           VGDP   V+
Sbjct: 1062 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNS----------VGDPAPAVK 1111

Query: 1746 WLRNG----VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
            W ++     +P+        +H  G   L ++ V  EDSG YTC A N  G       L 
Sbjct: 1112 WTKDSEDSAIPVSMDGH-RLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLL 1168

Query: 1802 VQ 1803
            VQ
Sbjct: 1169 VQ 1170



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKDGR----PVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD    V+W KD      PV          N     L +++V   D+G+YTC A N  G
Sbjct: 1103 VGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1159

Query: 992  QATTSANLTIVTKKD 1006
              T   NL +    D
Sbjct: 1160 FDTIIVNLLVQVPPD 1174


>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
          Length = 1299

 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 93/386 (24%), Positives = 162/386 (41%), Gaps = 49/386 (12%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P P+I W +E+  +  +    ++    K++ II  V   DS  +  +A+N  G    
Sbjct: 290  EGLPTPIIYWAKEDGMLPKNRT--VYKNFEKTLQIIH-VSEADSGNYQCIAKNALGAIHH 346

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            + ++ V+            P +    QN+ ++ G+   L  +  G     + WL NG  +
Sbjct: 347  TISVRVK----------AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPI 396

Query: 4555 Q--PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
            +  PD  ++ ++ D   T++      + S  Y+C A N  G    +A   V++ A     
Sbjct: 397  EIAPDDPSRKIDGD---TIIFSNVQERSSAVYQCNASNEYGYLLANA--FVNVLAE---- 447

Query: 4613 KPQTKAANAPPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
                     PP I+ P     +++A   A+   C   G PLPT+QW+KG K    + +  
Sbjct: 448  ---------PPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIQWFKGAK--GSALHED 495

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +    +  TL I  A  +  G Y CVA N  G       L++  P      P        
Sbjct: 496  IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYA----- 550

Query: 4731 VVYEGQPAQFKTQI--TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            VV  G    F+ ++     +  T+ WL++   +P    F +    +   L++ +  ++D+
Sbjct: 551  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV----DKDHLVVADVSDDDS 606

Query: 4789 GTFTCRATTAAGQVETSAKLVVKSKT 4814
            GT+TC A T    V  SA L V + T
Sbjct: 607  GTYTCVANTTLDSVSASAVLSVVAPT 632



 Score = 72.9 bits (171), Expect = 3e-11
 Identities = 78/308 (25%), Positives = 122/308 (39%), Gaps = 34/308 (11%)

Query: 4513 PPSFTL---TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
            PP+F      A N     G ++ L+    G     +YW K    +    +N+ + ++   
Sbjct: 262  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLP---KNRTVYKNFEK 318

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            TL I+     DSG Y+C+A N+ G             A       + KAA   P  I   
Sbjct: 319  TLQIIHVSEADSGNYQCIAKNALG-------------AIHHTISVRVKAA---PYWITAP 362

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
            ++ +++ G+     C+  G P P + W      I+ +     SR  D  T+  S      
Sbjct: 363  QNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAP-DDPSRKIDGDTIIFSNVQERS 421

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV-VYEGQPAQFKTQITSKI 4748
               Y+C A N  G +   A + V     A+    LTP   +  V   +PA          
Sbjct: 422  SAVYQCNASNEYGYLLANAFVNVL----AEPPRILTPANTLYQVIANRPALLDCAFFGSP 477

Query: 4749 KPTIQWLR--EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
             PTIQW +  +G+ + E  D  ++HE  N  L I    ++ TGT+TC A    G  +   
Sbjct: 478  LPTIQWFKGAKGSALHE--DIYVLHE--NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV 533

Query: 4807 KLVVKSKT 4814
             L +K  T
Sbjct: 534  HLEIKDPT 541



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 72/283 (25%), Positives = 115/283 (40%), Gaps = 18/283 (6%)

Query: 291 GNPRPRVTWFKNG-QRLINSNKHEIITTHNHTTLRVRNTQKSDSGH-YTLLAE-NPNGCI 347
           G P P + W  N  QRL  S +   ++   +  L   N    D+   Y   A  N    I
Sbjct: 167 GLPPPIIFWMDNSFQRLPQSER---VSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTI 223

Query: 348 VTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407
                ++V+  +   + D  +  ++DT+    +   E     L P+      +++   G 
Sbjct: 224 QQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE--GNASNKEELRGN 281

Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467
           +   +C   G P P + W   D  +  +      V ++    L I +V+ +DSG   C+A
Sbjct: 282 VLSLECIAEGLPTPIIYWAKEDGMLPKNRT----VYKNFEKTLQIIHVSEADSGNYQCIA 337

Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
           +N  G  A    ++V  K    AP ++     L +  GE   L  RA G P PRI+W  +
Sbjct: 338 KNALG--AIHHTISVRVK---AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTN 392

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           GVPI   P+       G  T+     +   +A YQC A N  G
Sbjct: 393 GVPIEIAPDDPSRKIDG-DTIIFSNVQERSSAVYQCNASNEYG 434



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 53/200 (26%), Positives = 84/200 (42%), Gaps = 16/200 (8%)

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR---DDYNHK 439
           I +  KA AP ++   Q+  ++ G+     CR  G P P ++W  N   I    DD + K
Sbjct: 348 ISVRVKA-APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 406

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           I         ++ +NV    S V  C A N+ G       +NV+ +     P+ +   +T
Sbjct: 407 I-----DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP----PRILTPANT 457

Query: 500 L-NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           L  V    P +L+    G+P P I W K       + ++ +  + G  TL+IP A+    
Sbjct: 458 LYQVIANRPALLDCAFFGSPLPTIQWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDST 515

Query: 559 AWYQCTAQNVAGSTATRARL 578
             Y C A+N  G       L
Sbjct: 516 GTYTCVARNKLGMAKNEVHL 535



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 71/318 (22%), Positives = 131/318 (41%), Gaps = 26/318 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSIL 4468
            P I T      +V  +  A  +  F G PLP I+W++       +   + +H   T  I 
Sbjct: 449  PRILTPANTLYQVIANRPALLDCAFFGSPLPTIQWFKGAKGSALHEDIYVLHENGTLEIP 508

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            + ++   + +  +  VA N+ G AK   +L +++          P       +   V  G
Sbjct: 509  VAQK---DSTGTYTCVARNKLGMAKNEVHLEIKD----------PTWIVKQPEYAVVQRG 555

Query: 4529 QLVRLDTKV--TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             +V  + KV    T  + V WLK+ +++  D R  + ++D    L++ +    DSG Y C
Sbjct: 556  SMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV-DKD---HLVVADVSDDDSGTYTC 611

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VA N+  ++   A  V+S+ A    P P     N P ++   L D++    Q        
Sbjct: 612  VA-NTTLDS-VSASAVLSVVAPTPTPAPVYDVPNPPLDL--ELTDQLDKSVQLSWTPGDD 667

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR--V 4704
               P+ T+     D + KP  +   +  +   T    +  P     ++ +A NS G+   
Sbjct: 668  NNSPITTIHDEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 727

Query: 4705 TVAAKLKVTQPDQADNLP 4722
            + A++  +T+  + D  P
Sbjct: 728  SEASEQYLTKASEPDKNP 745



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 46/180 (25%), Positives = 69/180 (38%), Gaps = 14/180 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP   T    +  +   + A  + +    G     I+WF   K       I  ++  G  
Sbjct: 448  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIQWFKGAKGSALHEDIYVLHENG-- 503

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LEI   +   +GTY+C A NK G A+  V LE  D      P +         ++ G  
Sbjct: 504  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD------PTWIVKQPEYAVVQRGSM 557

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              FEC V       + + W  + + +    R  TV     VV D++   + DSG Y C A
Sbjct: 558  VSFECKVKHDHTLSLTVLWLKDNRELPSDERF-TVDKDHLVVADVS---DDDSGTYTCVA 613



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 16/197 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RPP F T   +  +  E +        I  G  + +I W      +  +   RTVY    
Sbjct: 261  RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN---RTVYKNFE 317

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              L+I+     DSG Y C A N  G     ISV+++         P + T  QN+  L  
Sbjct: 318  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA-------PYWITAPQNLV-LSP 369

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+     C      +P  +I W  NG P+  +    +    G  ++  +  Q   S  Y 
Sbjct: 370  GEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQ 426

Query: 3224 CRAYNKYGEDFTRATIN 3240
            C A N+YG     A +N
Sbjct: 427  CNASNEYGYLLANAFVN 443



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V + G  + FEC V+     +L + W  +N+ LPS  R+    D   V+ D++   ++DS
Sbjct: 551  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVS---DDDS 606

Query: 2844 GIYTCKATNSKGSATTSGSL 2863
            G YTC A  +  S + S  L
Sbjct: 607  GTYTCVANTTLDSVSASAVL 626



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 265 PPKIAQKPRNSKLQEGAD--AQFQVQLSGNPRPRVTWFKNGQRLINSNKHE-IITTHNHT 321
           PP+I   P N+  Q  A+  A       G+P P + WFK  +    S  HE I   H + 
Sbjct: 448 PPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIQWFKGAK---GSALHEDIYVLHENG 503

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           TL +   QK  +G YT +A N  G      +L ++ PT
Sbjct: 504 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 541



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP +  A  N+    G +  L CR    G+   R+ W  NG PI+      P+ +
Sbjct: 350  VRVKAAPYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPD-DPSRK 406

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
             D   +   +V    S VY C A+N+ G  + +  + V+A+   IL
Sbjct: 407  IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRIL 452



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 75/331 (22%), Positives = 119/331 (35%), Gaps = 31/331 (9%)

Query: 3042 DDTGRPPEFTTVF-KD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGK--TIEASHRI 3097
            +D  +PP  T    KD I+D  E  +   EA     G       W  NG    I+    +
Sbjct: 35   EDLVQPPTITQQSPKDYIIDPRENIVIQCEAK----GKPPPSFSWTRNGTHFDIDKDPLV 90

Query: 3098 RTVYAFGMVVLEIL--GTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHI 3155
                  G +++ I+  G   T  G Y C A N+ G A   V    V +   + P +T   
Sbjct: 91   TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA---VSNNIVVRPS-RSPLWTKEK 146

Query: 3156 QNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-QPMRHSTRIKTVSDFGFVVLDIAYT 3214
                 L+ GQS    C   P+  P   I W  N  Q +  S R+    +      ++   
Sbjct: 147  LEPITLQSGQSLVLPCRP-PIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 205

Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
               +  +Y+C  Y ++    T           + ++ L     A + + E   GA+    
Sbjct: 206  DTRE--DYIC--YARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE-FYGAKSSRE 260

Query: 3275 STPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR-YRT 3333
                  PP F+T   + +   E +        +    P   + W      LP     Y+ 
Sbjct: 261  -----RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKN 315

Query: 3334 FHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            F       L I++  E +SG Y+C+A N LG
Sbjct: 316  FEK----TLQIIHVSEADSGNYQCIAKNALG 342



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            + +  P +++ P  + +  GE     CR  G+PKPR+ WL NG
Sbjct: 351  RVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 393



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 7/117 (5%)

Query: 1167 YQIEEISKSKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            Y  +   +  P F+ P  N     E  G  + LEC  E  G PT  + W      +    
Sbjct: 253  YGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE--GLPTPIIYWAKEDGMLP--- 307

Query: 1225 RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281
            + +T Y      L IIH + AD+G Y   A N LG+ H +  VRV      +T  QN
Sbjct: 308  KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN 364



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980
            ++ G    FE +++     +L V WLKD R + +  R T   +     L +  V+  D+G
Sbjct: 552  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 607

Query: 981  HYTCRAYNAIGQATTSANLTIV 1002
             YTC A   +   + SA L++V
Sbjct: 608  TYTCVANTTLDSVSASAVLSVV 629



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            +  G    FE +V+    L++TV W  + +++ S  R     D     L +A V  +DSG
Sbjct: 552  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 607

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
             YT VA         SA ++V
Sbjct: 608  TYTCVANTTLDSVSASAVLSV 628



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 45/172 (26%), Positives = 68/172 (39%), Gaps = 9/172 (5%)

Query: 4622 PPEIIEPL-KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            PP I +   KD I+   + I   C+  GKP P+  W +        K   ++      TL
Sbjct: 40   PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 99

Query: 4681 RI---SEAFPED-EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
             I   SE   E  EG Y+C A N  G   V+  + V +P ++  L     L  I +  GQ
Sbjct: 100  IINIMSEGKAETYEGVYQCTARNERG-AAVSNNI-VVRPSRSP-LWTKEKLEPITLQSGQ 156

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
                  +    + P I +  + +     P  + + +G N  L   N   EDT
Sbjct: 157  SLVLPCRPPIGLPPPIIFWMDNS-FQRLPQSERVSQGLNGDLYFSNVLPEDT 207



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 272 PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
           P+N  L  G D     + +GNP+PR++W  NG   I     +     +  T+   N Q+ 
Sbjct: 362 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVP-IEIAPDDPSRKIDGDTIIFSNVQER 420

Query: 332 DSGHYTLLAENPNGCIVTSGYLAV 355
            S  Y   A N  G ++ + ++ V
Sbjct: 421 SSAVYQCNASNEYGYLLANAFVNV 444



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            AEPP+ +T    + +++  + A  +        P   ++WF   K           H+ G
Sbjct: 446  AEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIQWFKGAKGSALHEDIYVLHENG 503

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
               L+I    ++++G Y CVA NKLG    + +L+
Sbjct: 504  T--LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 536



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 8/90 (8%)

Query: 2372 TRQRP-VFTQPLQNIDNIQE--GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428
            +R+RP  F  P  N  N +E  G     +C  I  G PT  + W + + ++  +  + K 
Sbjct: 258  SRERPPTFLTPEGNASNKEELRGNVLSLEC--IAEGLPTPIIYWAKEDGMLPKNRTVYKN 315

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             +    ++ I HV + D G Y C A N LG
Sbjct: 316  FE---KTLQIIHVSEADSGNYQCIAKNALG 342



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 3/102 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P + T P +L+LS        CR     +   R+ W  NG P+       +    G  I+
Sbjct: 356  PYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 413

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
                V +R + +Y C A+N +G    +  + V      IL P
Sbjct: 414  -FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 454



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 43/170 (25%), Positives = 63/170 (37%), Gaps = 16/170 (9%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           DC   G P P + WF   +  +    H+ +     N  L I       +G  TCVARNK 
Sbjct: 470 DCAFFGSPLPTIQWF---KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 526

Query: 472 GETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTPRIT--WQKDG 528
           G    +  L + +   +V  P++        V+ G  V    +     T  +T  W KD 
Sbjct: 527 GMAKNEVHLEIKDPTWIVKQPEYAV------VQRGSMVSFECKVKHDHTLSLTVLWLKDN 580

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +P+ E R   D     L +      D+  Y C A     S +  A L
Sbjct: 581 RE-LPSDE-RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVL 626



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P ++ +      V  G  V FECK++     +L V W K+ + +    RF    D   VA
Sbjct: 540  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA 599

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540
             D+ D   +DSG YTC A   + +   S  L+  + T
Sbjct: 600  -DVSD---DDSGTYTCVANTTLDSVSASAVLSVVAPT 632



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/86 (30%), Positives = 32/86 (37%), Gaps = 4/86 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PPR          V    P   DC     G P   I WF   +  A    ++ L++ G  
Sbjct: 448  PPRILTPANTLYQVIANRPALLDCAF--FGSPLPTIQWFKGAKGSALHEDIYVLHENG-- 503

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSA 3779
             L+I        G YTC A NK G A
Sbjct: 504  TLEIPVAQKDSTGTYTCVARNKLGMA 529



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 12/159 (7%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP   T  + L  +  N  A  +C           ++WF   K       +  +++ G  
Sbjct: 448  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIQWFKGAKGSALHEDIYVLHENG-- 503

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ-- 3673
             LEI    +   G YTC A N+ G A     L++K    I+ +P+     +    S +  
Sbjct: 504  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 563

Query: 3674 -KLEETLHKREEITIED--EKPNPPRFTVEIKDNIDVPE 3709
             K + TL     + ++D  E P+  RFTV+ KD++ V +
Sbjct: 564  VKHDHTL-SLTVLWLKDNRELPSDERFTVD-KDHLVVAD 600



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           P I +Q  K+       N   + + +G P P  SWTR            +     TG + 
Sbjct: 41  PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 100

Query: 131 LLIKQIGPGD--EGEYTCTARNQYGEAIC-SVYIQP 163
           + I   G  +  EG Y CTARN+ G A+  ++ ++P
Sbjct: 101 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRP 136



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 8/100 (8%)

Query: 3829 PPKFIT-QIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            PP F+T +  +   EE  G  +  EC  E    P   I W +   +LP     RTVY   
Sbjct: 262  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPI--IYWAKEDGMLPKN---RTVYKNF 316

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              +L I++V   DSG Y C A N  G      ++  K  P
Sbjct: 317  EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 356



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G+PK R+ WL NGVPIE +    +    G   +    V    S  Y C A NE G
Sbjct: 381  GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYG 434



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 3813 RGRISDAPKEEPI-VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            R ++  A  E  + +  P   + Q +   V+    V FEC+V+      L + W ++ + 
Sbjct: 523  RNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRE 582

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906
            LPS  R+    D     L +  V  +DSG Y C A
Sbjct: 583  LPSDERFTVDKD----HLVVADVSDDDSGTYTCVA 613



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P ++        ++ G    FEC+V+  +   LT+ W  + +++ +  R+    D   VA
Sbjct: 540  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA 599

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             D+     +DSGTY C A   L     +  L V
Sbjct: 600  -DV---SDDDSGTYTCVANTTLDSVSASAVLSV 628



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1589 IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSG 1648
            ++ G    FE ++      +L V W  +N+ L S  RFT   +   V  D+     +DSG
Sbjct: 552  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSD---DDSG 607

Query: 1649 TYTCRAINALGEAVTSGIAIV 1669
            TYTC A   L     S +  V
Sbjct: 608  TYTCVANTTLDSVSASAVLSV 628



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            I+WFK          +    + G  TL I   + D +G YTC A N LG A +   ++I+
Sbjct: 481  IQWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 538

Query: 2736 DRHWLL 2741
            D  W++
Sbjct: 539  DPTWIV 544



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 7/110 (6%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVE-GQVLHLEGQVEPKNDPDLKIEWYFNG 2951
            AR   G   +    E   P WI+    E+ +V+ G ++  E +V+  +   L + W  + 
Sbjct: 522  ARNKLGMAKNEVHLEIKDPTWIVK-QPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDN 580

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + L    RF +  D     L + DV + DSG YTC A N   ++ ++S V
Sbjct: 581  RELPSDERFTVDKDH----LVVADVSDDDSGTYTCVA-NTTLDSVSASAV 625



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 6/94 (6%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-YRTTHDFGYV 2167
            P  LT   +L  +     A  +C       P  TI WF  G K  A H      H+ G  
Sbjct: 449  PRILTPANTLYQVIANRPALLDCAF--FGSPLPTIQWF-KGAKGSALHEDIYVLHENG-- 503

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L+I     + +GTY C A NKLG A N   L++
Sbjct: 504  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI 537



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 24/107 (22%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + PR +T  N   ++   + A  +C     P P   ++W+   K           ++ G 
Sbjct: 447  EPPRILTPANTLYQVIANRPALLDCAFFGSPLPT--IQWFKGAKGSALHEDIYVLHENG- 503

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
              L+I     + +G YTC A N LG A + + L ++    I++  ++
Sbjct: 504  -TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEY 549



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G+ V  EC+++     ++ V W  + + + +  RF      D   L +  V  +DSG YT
Sbjct: 555  GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 610

Query: 1385 CQATNQLGEAVTSCALRVIA 1404
            C A   L     S  L V+A
Sbjct: 611  CVANTTLDSVSASAVLSVVA 630



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 52/224 (23%), Positives = 87/224 (38%), Gaps = 18/224 (8%)

Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG-QSIEASSRFTSIFRFGYISLDMLSL 701
           L+ +T   G  +    R  P+G P   I W+ N  Q +  S R +          ++L  
Sbjct: 147 LEPITLQSGQSLVLPCR-PPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 205

Query: 702 NIQDSGEYTCRA-VSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQE 760
           + ++  +Y C A  + T   + K  + V   +  E      +T+     L D   Y  + 
Sbjct: 206 DTRE--DYICYARFNHTQTIQQKQPISVKVISVDELN----DTIA--ANLSDTEFYGAKS 257

Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           S E      P F+ P  +    +E R      +      PT  + W K+   +  +  + 
Sbjct: 258 SRERP----PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 313

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
             F     +L I+H+   D+G+Y   A N LG    T S+RV A
Sbjct: 314 KNFE---KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 354



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P +I +      +  G    +EC+++     ++ V W  + + L S  R+    D     
Sbjct: 540  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH---- 595

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            L +  V  +DSG YTC A   L    +S  L+V
Sbjct: 596  LVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 628



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 9/120 (7%)

Query: 637 PQFIVPLKSVTAME-GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           P +IV       ++ G  + FE +++     ++ + WLK+ + + +  RFT         
Sbjct: 540 PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDH 595

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV---TPR-ATIERTSQHPETLQYIQQLE 751
           L +  ++  DSG YTC A +        AVL V   TP  A +      P  L+   QL+
Sbjct: 596 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPLDLELTDQLD 655



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 4/91 (4%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P +I +  +   +  G    FE ++       L V W  + ++LP   R+    D  +V+
Sbjct: 540  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVV 598

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             D+    +++SG Y CVA   L   S  A L
Sbjct: 599  ADV---SDDDSGTYTCVANTTLDSVSASAVL 626



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q G    F+C++      +L V W ++ + +    R T   D     + ++ V D+D G
Sbjct: 552  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVADVSDDDSG 607

Query: 2448 VYMCRASNLL 2457
             Y C A+  L
Sbjct: 608  TYTCVANTTL 617



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 6/97 (6%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT--WFKNGQRLINSNKHEIITTHNHTT 322
           P  I ++P  + +Q G+   F+ ++  +    +T  W K+ + L +  +  +   H    
Sbjct: 540 PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH---- 595

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           L V +    DSG YT +A      +  S  L+V +PT
Sbjct: 596 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPT 632



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 4/97 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            E  +P      P   ++   S   FEC++   +  S+ V W  + + L +  R     D 
Sbjct: 536  EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 595

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                L +  V   D+G YTC A       + S  L V
Sbjct: 596  ----LVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 628



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 3/67 (4%)

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           G  + L   A G PTP I W K+   +   P+ R        TL I     +D+  YQC 
Sbjct: 280 GNVLSLECIAEGLPTPIIYWAKEDGML---PKNRTVYKNFEKTLQIIHVSEADSGNYQCI 336

Query: 565 AQNVAGS 571
           A+N  G+
Sbjct: 337 AKNALGA 343



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + PR L P     +++  + A  +      S L  T++W+   K       I   H+ 
Sbjct: 445  LAEPPRILTPANTLYQVIANRPALLDCAFFG-SPLP-TIQWFKGAKGSALHEDIYVLHEN 502

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            G   L+I   + + +G YT VARN  G A+    + ++
Sbjct: 503  G--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 538



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 7/93 (7%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVT--WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
           V  G M  F+C+V       +T  W  ++R++  D   +  V++  +H L++ +V+  DS
Sbjct: 552 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSD--ERFTVDK--DH-LVVADVSDDDS 606

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
           G  TCVA       +    L+V+      AP +
Sbjct: 607 GTYTCVANTTLDSVSASAVLSVVAPTPTPAPVY 639


>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhesion
            molecule 2 protein.
          Length = 2113

 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 89/365 (24%), Positives = 147/365 (40%), Gaps = 47/365 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAK 4493
            G P+P I+W ++  P+     +      TK I  L I  +  EDS  +     N  G+A+
Sbjct: 311  GYPIPAIRWLKDGRPLPADSRW------TKRITGLTISDLRTEDSGTYICEVTNTFGSAE 364

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  L+V          I P   TLT + +    G  V L   +TG+    + W +N + 
Sbjct: 365  ATGILMV----------IDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTEL 414

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            V PD    I       TLLI  A    SG Y+C A   A  A+  A  +++L        
Sbjct: 415  VLPDEAISIRGLSNE-TLLITSAQKSHSGAYQCFATRKAQTAQDFA--IIALE------- 464

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK-LIKPSKYFQMS 4672
                  +  P I+    +K+V  G+     C   G P PTV W   D+ +++   +    
Sbjct: 465  ------DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQ 518

Query: 4673 RTADEYT----LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             T  + T    + ++     D G Y+C A N  G     A++ V  P      P++  +R
Sbjct: 519  YTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP------PSIRAMR 572

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            +I    G+      ++      +I+W ++  L+P+    Q++ E N  + L       D 
Sbjct: 573  NITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDN-HRQVVFE-NGTLKLTDVQKGMDE 630

Query: 4789 GTFTC 4793
            G + C
Sbjct: 631  GEYLC 635



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 53/178 (29%), Positives = 79/178 (44%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C +TG P   + W+ N   +  D    I +    N  L+IT+   S SG   C
Sbjct: 389 GSTVILSCALTGSPEFTIRWYRNTELVLPD--EAISIRGLSNETLLITSAQKSHSGAYQC 446

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
            A  K+ +TA    +  +E      P+ V  FS   V  GE   L   A G P P +TW 
Sbjct: 447 FATRKA-QTAQDFAIIALEDG---TPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWA 502

Query: 526 KDGVPIIPNPELRIH----TDGGA-STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+ +   R +    +DG   S +++   +  D   Y+CTA+N+ GS   +AR+
Sbjct: 503 LDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARI 560



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 92/426 (21%), Positives = 162/426 (38%), Gaps = 37/426 (8%)

Query: 4393 KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK 4452
            KAQT +      ++   P I +   +   V   EQ        G P P + W  ++ PI 
Sbjct: 451  KAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQFSLMCAAKGAPPPTVTWALDDEPIV 509

Query: 4453 NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
                 + + ++      I  + V    +        GG  +C+A  +V     Q R  + 
Sbjct: 510  RDGSHRTNQYTMSDGTTISHMNVTGPQI------RDGGVYRCTARNLVGSAEYQARINVR 563

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
             P      +N+   +G+   ++ +V G     + W K+   + PD   +++ E+GT  L 
Sbjct: 564  GPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGTLKLT 622

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
             ++    D G+Y C               V+  P           A   PP +I+P +  
Sbjct: 623  DVQK-GMDEGEYLC--------------SVLIQPQLSISQSVHV-AVKVPP-LIQPFEFP 665

Query: 4633 IVAEGQAIEFSCKIVGKPLPT-VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              + GQ +   C +    +P  + W K  ++I       +       +L+IS    +  G
Sbjct: 666  PASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNG 725

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            +Y C+A N+A  V+   +L V  P +      + P     +Y G+       +     P 
Sbjct: 726  NYTCIASNAAATVSRERQLIVRVPPRF----VVQPNNQDGIY-GKAGVLNCSVDGYPPPK 780

Query: 4752 IQWLR-EGALIPE----TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG-QVETS 4805
            + W   +G+  P+     P    I    N+ LLI +  EED G + C+A+   G  +  S
Sbjct: 781  VMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKS 840

Query: 4806 AKLVVK 4811
              L VK
Sbjct: 841  MFLTVK 846



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 71/177 (40%), Gaps = 12/177 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHAL 450
           P+ V    ++ V  G+     C   G P P VTW ++D  I  D +H+      S    +
Sbjct: 468 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 527

Query: 451 MITNVT---LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
              NVT   + D GV  C ARN  G   +Q R+N      V  P  +     +    G  
Sbjct: 528 SHMNVTGPQIRDGGVYRCTARNLVGSAEYQARIN------VRGPPSIRAMRNITAVAGRD 581

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            ++N R +G P   I W KD + +  N    +  +G     D+   K  D   Y C+
Sbjct: 582 TLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDV--QKGMDEGEYLCS 636



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 67/273 (24%), Positives = 107/273 (39%), Gaps = 27/273 (9%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS-GKYECVAINS-AGEARCDAECV 4602
            V W K+   + P+ R  I    G Y   I +   +D+   Y C+  +  +GE R      
Sbjct: 219  VSWEKDTVSIIPEHRFFITYHGGLY---ISDVQKEDALSTYRCITKHKYSGETRQSNGAR 275

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
            +S+          T  A + P I++    + V  G  +E  C   G P+P ++W K  + 
Sbjct: 276  LSV----------TDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRP 325

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
            +     +    T     L IS+   ED G Y C   N+ G       L V  P       
Sbjct: 326  LPADSRWTKRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHV---- 377

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG-NNAVLLIG 4781
             LTP + +    G        +T   + TI+W R   L+   PD  +   G +N  LLI 
Sbjct: 378  TLTP-KKLKTGIGSTVILSCALTGSPEFTIRWYRNTELV--LPDEAISIRGLSNETLLIT 434

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            +  +  +G + C AT  A   +  A + ++  T
Sbjct: 435  SAQKSHSGAYQCFATRKAQTAQDFAIIALEDGT 467



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 51/190 (26%), Positives = 80/190 (42%), Gaps = 16/190 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T  +CRV G PY  + W+  D  +  D NH+ +V E+G   L 
Sbjct: 565 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWY-KDALLLPD-NHRQVVFENGT--LK 620

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +T+V    D G   C           Q +L++ +   V    P  ++ F       G+ +
Sbjct: 621 LTDVQKGMDEGEYLC-------SVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLL 673

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +         P RITW+KDG  II    + I +    S+L I          Y C A N
Sbjct: 674 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 733

Query: 568 VAGSTATRAR 577
            A +T +R R
Sbjct: 734 -AAATVSRER 742



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 67/291 (23%), Positives = 102/291 (35%), Gaps = 36/291 (12%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I W ++   I +     I +    S L I  V ++ +  +  +A N   T      L+V 
Sbjct: 688  ITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVR 747

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK-----NGKKVQP 4556
                      VPP F +   N +   G+   L+  V G  P  V W       N ++  P
Sbjct: 748  ----------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHP 797

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
                  ++     +LLI     +D G Y C A N  G                D  K   
Sbjct: 798  VPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGT---------------DISKSMF 842

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS---KYFQMSR 4673
                 P  I       I  +G A E +C   G+    ++W KGD +I P    +Y   ++
Sbjct: 843  LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 902

Query: 4674 TADEYTLRISEAFPEDEGD---YKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
               +  +   +  P D GD   + C A NS G      +L V +P     L
Sbjct: 903  DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPEL 953



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 50/186 (26%), Positives = 77/186 (41%), Gaps = 15/186 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTG--RPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           P  V+V +D+    G +  F C +    + Y  V  +  D  +     H+  +   G   
Sbjct: 186 PYTVRV-EDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDT-VSIIPEHRFFITYHGG-- 241

Query: 450 LMITNVTLSDS-GVVTCVARNK-SGETAFQ--CRLNVIEKEQVVAPKFVERFSTLNVREG 505
           L I++V   D+     C+ ++K SGET      RL+V +  + + P  ++ F +  V  G
Sbjct: 242 LYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESI-PTILDGFHSQEVWAG 300

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             V L   A G P P I W KDG P+  +        G    L I   +  D+  Y C  
Sbjct: 301 HTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG----LTISDLRTEDSGTYICEV 356

Query: 566 QNVAGS 571
            N  GS
Sbjct: 357 TNTFGS 362



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 20/185 (10%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            S GQ+  Y   ++ +GD  + I W  +G+ I +   +       M  L+I       +G 
Sbjct: 668  SIGQLL-YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGN 726

Query: 3121 YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
            Y+C A+N    A +S + + + +     PRF     N +G+  G++    C+V     P 
Sbjct: 727  YTCIASN--AAATVSRERQLIVR---VPPRFVVQPNNQDGIY-GKAGVLNCSVDGYPPP- 779

Query: 3181 MKIEWYH---NGQPMRH-----STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             K+ W H   +G P ++     + RI+ + +   +   I +    D G Y+C+A N  G 
Sbjct: 780  -KVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL---IRHVLEEDIGYYLCQASNGVGT 835

Query: 3233 DFTRA 3237
            D +++
Sbjct: 836  DISKS 840



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 13/148 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W  +G+ + A  R  T    G+ + ++   +T DSGTY C  TN +G AE +  L  +
Sbjct: 317  IRWLKDGRPLPADSRW-TKRITGLTISDL---RTEDSGTYICEVTNTFGSAEATGILMVI 372

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            D      P   T     + LK G  +    +      P+  I WY N + +     I ++
Sbjct: 373  D------PLHVT--LTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI-SI 423

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229
                   L I   Q   SG Y C A  K
Sbjct: 424  RGLSNETLLITSAQKSHSGAYQCFATRK 451



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 58/275 (21%), Positives = 99/275 (36%), Gaps = 17/275 (6%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVSLLIKQIGPG--DEGEYTCTARNQY 152
           +G P P V+W     P+V    + + +Y    G     +   GP   D G Y CTARN  
Sbjct: 492 KGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLV 551

Query: 153 GEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
           G A     I   G                    +  +  G   Y+ +  +    +     
Sbjct: 552 GSAEYQARINVRGPPSIRAMRNITAVAGR-DTLINCRVIGYPYYSIKWYKDALLLP---- 606

Query: 213 TDHSSTDDFKVDTFEYRLLREVSFRESITK-RYVGESDVQISTEIDRSLG-PVSPPKIAQ 270
                 D+ +   FE   L+    ++ + +  Y+    +Q    I +S+   V  P + Q
Sbjct: 607 ------DNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQ 660

Query: 271 KPRNSKLQEGADAQFQVQLSGNPRP-RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQ 329
                    G        +S    P R+TW K+GQ +I+ +   I +    ++L++ +  
Sbjct: 661 PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVS 720

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
              +G+YT +A N    +     L V  P    VQ
Sbjct: 721 LKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQ 755



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPIIPNPELR 538
            IE       K +    T+     + V L   +VG P P + W KD     +P+  +    
Sbjct: 1342 IEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRL 1401

Query: 539  IHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            IHT+G   TL +   KA D+ +Y CTA N  G
Sbjct: 1402 IHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1430



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 4/72 (5%)

Query: 791 EAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNK 850
           E   T    P   + W KDGRP+ A SR T         L I  LR ED+G+Y     N 
Sbjct: 304 ELPCTASGYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNT 359

Query: 851 LGEAISTASIRV 862
            G A +T  + V
Sbjct: 360 FGSAEATGILMV 371



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 53/246 (21%), Positives = 103/246 (41%), Gaps = 16/246 (6%)

Query: 338 LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
           LL +N    +  +G L +    +   + +    +    Q    + + ++ K   P  ++ 
Sbjct: 604 LLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKV--PPLIQP 661

Query: 398 CQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            +    + G++    C V+    P  +TW   D Q+    +   + ++    +L I++V+
Sbjct: 662 FEFPPASIGQLLYIPCVVSSGDMPIRITWR-KDGQVIISGSGVTIESKEFMSSLQISSVS 720

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
           L  +G  TC+A N +   + + +L V      V P+FV + +  +   G+  VLN    G
Sbjct: 721 LKHNGNYTCIASNAAATVSRERQLIVR-----VPPRFVVQPNNQDGIYGKAGVLNCSVDG 775

Query: 517 TPTPRITWQK---DGVPIIPNP---ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P P++ W+     G P   +P     RI     +S L I      D  +Y C A N  G
Sbjct: 776 YPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL-IRHVLEEDIGYYLCQASNGVG 834

Query: 571 STATRA 576
           +  +++
Sbjct: 835 TDISKS 840



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 3/105 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P +   A  G  ++    +   GD  ++I W K+GQ I + S  T   +    SL
Sbjct: 656 PPLIQPFEFPPASIGQLLYIPCVVSS-GDMPIRITWRKDGQVIISGSGVTIESKEFMSSL 714

Query: 697 DMLSLNIQDSGEYTCRA--VSATGVAETKAVLHVTPRATIERTSQ 739
            + S++++ +G YTC A   +AT   E + ++ V PR  ++  +Q
Sbjct: 715 QISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQ 759



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLKDGRP+ A SR T         LTI  +   D+G Y C   N  G A  +  L ++
Sbjct: 317  IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 372



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 49/189 (25%), Positives = 72/189 (38%), Gaps = 14/189 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI----LVNESGN 447
           P+FV    ++D   GK    +C V G P P+V W            H +     +    N
Sbjct: 750 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 809

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            +L+I +V   D G   C A N  G    +     ++    +        +T    +G  
Sbjct: 810 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVK----IPAMITSHPNTTIAIKGHA 865

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELR--IHT-DGG---ASTLDIPRAKASDAAWY 561
             LN  A G     I W+K    I P+  +R  I T D G    STL +  A   D+ ++
Sbjct: 866 KELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFF 925

Query: 562 QCTAQNVAG 570
            C A N  G
Sbjct: 926 SCHAINSYG 934



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/81 (27%), Positives = 38/81 (46%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD  +R+ W KDG+ + + S +T        +L I SV++   G+YTC A NA    +  
Sbjct: 682  GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRE 741

Query: 997  ANLTIVTKKDIIAESQHPGGL 1017
              L +      + +  +  G+
Sbjct: 742  RQLIVRVPPRFVVQPNNQDGI 762



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
            EV  GH V L  T +    P +R  W  +GRP+    R+ T    G    D+     ED+
Sbjct: 296  EVWAGHTVELPCTASGYPIPAIR--WLKDGRPLPADSRW-TKRITGLTISDLR---TEDS 349

Query: 2048 GTYMCKATNAVGEAVTTSSVKV 2069
            GTY+C+ TN  G A  T  + V
Sbjct: 350  GTYICEVTNTFGSAEATGILMV 371



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 17/162 (10%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L+IR V  ED   +   A N  GT   S ++ +  K        +P   T        
Sbjct: 810  SSLLIRHVLEEDIGYYLCQASNGVGT-DISKSMFLTVK--------IPAMITSHPNTTIA 860

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD--IRNKILEED-GTYTLLILEAYPQDSG 4582
              G    L+    G +PI + W K    + PD  +R  I  +D G   +  L+  P D G
Sbjct: 861  IKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRG 920

Query: 4583 K---YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
                + C AINS GE R   +  V  P   D P+ + +   A
Sbjct: 921  DSVFFSCHAINSYGEDRGLIQLTVQEP--PDPPELEIREVKA 960



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 6/76 (7%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G  +   C    S  P   I W  + +PLP+ +R+          L I+    EDSG Y 
Sbjct: 300  GHTVELPCTA--SGYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYI 353

Query: 2848 CKATNSKGSATTSGSL 2863
            C+ TN+ GSA  +G L
Sbjct: 354  CEVTNTFGSAEATGIL 369



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            + W  + +PL + SR+T+        L I     EDSGTY C   N  G A  +GI +V
Sbjct: 317  IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMV 371



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   I WLK+G+ + A SR+T         L +  L  +DSG Y C   +  G AE  
Sbjct: 311 GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 366

Query: 724 AVLHV 728
            +L V
Sbjct: 367 GILMV 371



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 9/110 (8%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV  PP+F+ Q  +      +     C V+    PK  + W ++ K   +  +Y  V   
Sbjct: 745  IVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPK--VMW-KHAKGSGNPQQYHPVPLT 801

Query: 3885 GFV------SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            G +      SL I +V  ED G Y+C+A N  G D +K+     K+P +I
Sbjct: 802  GRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 851



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/135 (24%), Positives = 51/135 (37%), Gaps = 13/135 (9%)

Query: 1276 VTDTQNEQAIEQIQLL-----EDAARRTKQVREDIT--VMQAPQFSRALHNIETVEGTNV 1328
            ++D Q E A+   + +         R++   R  +T      P      H+ E   G  V
Sbjct: 244  ISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTV 303

Query: 1329 HLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT 1388
             L C     G     + W  +G+P+    R+          L +  +  EDSG Y C+ T
Sbjct: 304  ELPCTAS--GYPIPAIRWLKDGRPLPADSRWTKRI----TGLTISDLRTEDSGTYICEVT 357

Query: 1389 NQLGEAVTSCALRVI 1403
            N  G A  +  L VI
Sbjct: 358  NTFGSAEATGILMVI 372



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++G P+ A +R T         L +  +  EDSGTY C   N  G A  +
Sbjct: 311  GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEAT 366

Query: 1798 STLFV 1802
              L V
Sbjct: 367  GILMV 371



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            I W K+G  L   +R        +  L+I+ LR +DSG Y C+ TN  G A +T  + + 
Sbjct: 317  IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 372

Query: 2736 D 2736
            D
Sbjct: 373  D 373



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 4/135 (2%)

Query: 3800 PQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            PQ   G   +   R  +  A  +  I    P  I  +++ T          CRV     P
Sbjct: 535  PQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGY--P 592

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               I+WY++  LLP  HR + V++ G + L  +     D GEY+C  +       +++  
Sbjct: 593  YYSIKWYKDALLLPDNHR-QVVFENGTLKLTDVQ-KGMDEGEYLCSVLIQPQLSISQSVH 650

Query: 3920 SCKKLPDIILQNQVP 3934
               K+P +I   + P
Sbjct: 651  VAVKVPPLIQPFEFP 665



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 43/174 (24%), Positives = 72/174 (41%), Gaps = 16/174 (9%)

Query: 3063 GQIAHYEASLIPTGDQSMV--IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            G +A ++  LIP+  Q  V  + W  +  +I   HR    Y  G+ + ++   K     T
Sbjct: 199  GNVAVFKC-LIPSSVQEYVSVVSWEKDTVSIIPEHRFFITYHGGLYISDV--QKEDALST 255

Query: 3121 YSCRATNKW-GQAEIS--VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            Y C   +K+ G+   S   +L   D ++   P       + E +  G +    CT     
Sbjct: 256  YRCITKHKYSGETRQSNGARLSVTDPAESI-PTILDGFHSQE-VWAGHTVELPCTASGYP 313

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             P   I W  +G+P+   +R  T    G  + D+   +  DSG Y+C   N +G
Sbjct: 314  IP--AIRWLKDGRPLPADSRW-TKRITGLTISDL---RTEDSGTYICEVTNTFG 361



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/174 (23%), Positives = 64/174 (36%), Gaps = 13/174 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W+ N + +     I ++       L I   + + SG Y C AT K   A+ 
Sbjct: 399  TGSPEFTIRWYRNTELVLPDEAI-SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 457

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-- 3192
               +   D +      F+  + N      G+     C       P   + W  + +P+  
Sbjct: 458  FAIIALEDGTPRIVSSFSEKVVN-----PGEQFSLMCAAKGAPPPT--VTWALDDEPIVR 510

Query: 3193 --RHSTRIKTVSDFGFVV-LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
               H T   T+SD   +  +++   Q  D G Y C A N  G    +A IN  G
Sbjct: 511  DGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG 564



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 4436 GEPLPLIKWYREN----FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
            G+P P +KW +++     P+       IHT  T   L++R V  EDS  +   A N GG 
Sbjct: 1375 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT---LLLRAVKAEDSGYYTCTATNTGGF 1431

Query: 4492 AKCSANLVVEEKRRQGR 4508
                 NL+V+    Q R
Sbjct: 1432 DTIIVNLLVQVPPDQPR 1448



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 5/101 (4%)

Query: 3441 EARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNN 3500
            E   T +  P   + W  +G+ L A SR+          L IS    EDSG Y+C   N 
Sbjct: 304  ELPCTASGYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNT 359

Query: 3501 YGEAVTTASMKVQGKRNIIL-ESQLPKGMEGTIDKIAALEG 3540
            +G A  T  + V    ++ L   +L  G+  T+    AL G
Sbjct: 360  FGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTG 400



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/124 (22%), Positives = 47/124 (37%), Gaps = 1/124 (0%)

Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
           S E    L  + P  +   P+  K   G+       L+G+P   + W++N + ++     
Sbjct: 362 SAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI 421

Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYIT 372
            I    N T L + + QKS SG Y   A            +A+E  T   V     + + 
Sbjct: 422 SIRGLSNETLL-ITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVN 480

Query: 373 DTQQ 376
             +Q
Sbjct: 481 PGEQ 484



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/104 (32%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG--DKLIKPSKY-FQMSRT 4674
            A  AP +II           + +   C  VG P P V+W K   D  I  S    ++  T
Sbjct: 1345 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHT 1404

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQ 4717
                 LR  +A  ED G Y C A N+ G  T+   L V   PDQ
Sbjct: 1405 NGTLLLRAVKA--EDSGYYTCTATNTGGFDTIIVNLLVQVPPDQ 1446



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 282  DAQFQVQLSGNPRPRVTWFKNGQRL---INSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            D +      G+P P V W K+ +     ++ + H +I  H + TL +R  +  DSG+YT 
Sbjct: 1366 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLI--HTNGTLLLRAVKAEDSGYYTC 1423

Query: 339  LAENPNGCIVTSGYLAVESPTE 360
             A N  G       L V+ P +
Sbjct: 1424 TATNTGGFDTIIVNLLVQVPPD 1445



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 9/90 (10%)

Query: 1471 VTDSNLKVEWFKNGQ----PVTI-GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525
            V D    V+W K+ +    PV++ GHR   IH  G + L  +   AEDSG YTC A N  
Sbjct: 1374 VGDPAPAVKWTKDSEDSAIPVSMDGHRL--IHTNGTLLLRAVK--AEDSGYYTCTATNTG 1429

Query: 1526 GTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555
            G D +   L  +   D  R T ++     I
Sbjct: 1430 GFDTIIVNLLVQVPPDQPRLTVSKTSASSI 1459



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-- 3870
            RG  S+    EP    P K I+   + T    + VR  C      DP   ++W ++ +  
Sbjct: 1333 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCN--SVGDPAPAVKWTKDSEDS 1390

Query: 3871 LLP-SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             +P S   +R ++  G  +L +  V AEDSG Y C A N  G D     +  +  PD
Sbjct: 1391 AIPVSMDGHRLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPD 1445



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 6/77 (7%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            +V  G  V   C     G P   I W  +GRP    SR  T    G   L I  +   D+
Sbjct: 296  EVWAGHTVELPCTAS--GYPIPAIRWLKDGRPLPADSR-WTKRITG---LTISDLRTEDS 349

Query: 3766 GEYTCRATNKWGSATTT 3782
            G Y C  TN +GSA  T
Sbjct: 350  GTYICEVTNTFGSAEAT 366



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G T    C     G P   + W ++ + +   SR TK        +TIS +R ED G Y+
Sbjct: 300  GHTVELPCTAS--GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYI 353

Query: 2451 CRASNLLG 2458
            C  +N  G
Sbjct: 354  CEVTNTFG 361



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 5/120 (4%)

Query: 240 ITK-RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT 298
           ITK +Y GE+       +  +    S P I     + ++  G   +     SG P P + 
Sbjct: 259 ITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIR 318

Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           W K+G+ L   ++     T   T L + + +  DSG Y     N  G    +G L V  P
Sbjct: 319 WLKDGRPLPADSR----WTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 374



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +    C    YP P +R  W  +G+ L +  R+ T    G    D+ T   EDSG Y 
Sbjct: 300  GHTVELPCTASGYPIPAIR--WLKDGRPLPADSRW-TKRITGLTISDLRT---EDSGTYI 353

Query: 1919 CKAINNLGQA 1928
            C+  N  G A
Sbjct: 354  CEVTNTFGSA 363



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 9/103 (8%)

Query: 53  ESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL 112
           +S+G R  +T   P E  P I +       +A G   +      G P P + W +   PL
Sbjct: 270 QSNGARLSVTD--PAESIPTILDGFHSQEVWA-GHTVELPCTASGYPIPAIRWLKDGRPL 326

Query: 113 VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
              ++++ R    TG   L I  +   D G Y C   N +G A
Sbjct: 327 PADSRWTKRI---TG---LTISDLRTEDSGTYICEVTNTFGSA 363



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 6/82 (7%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  +    S  V     V   C       P +R  W ++G+ LP+  R+          L
Sbjct: 286  PTILDGFHSQEVWAGHTVELPCTASGYPIPAIR--WLKDGRPLPADSRWTK----RITGL 339

Query: 3890 DILYVYAEDSGEYICRAVNDFG 3911
             I  +  EDSG YIC   N FG
Sbjct: 340  TISDLRTEDSGTYICEVTNTFG 361



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
            G P   + W  +G+PL   +R+T         +    +  EDSG Y+C  TN +G  E  
Sbjct: 311  GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 366

Query: 4061 AVI 4063
             ++
Sbjct: 367  GIL 369



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W  +G+ + A  R+ T    G    D+     EDSGTY+C+ TN  G A  T  
Sbjct: 313  PIPAIRWLKDGRPLPADSRW-TKRITGLTISDLR---TEDSGTYICEVTNTFGSAEATGI 368

Query: 2199 LKVAGHRNIIL 2209
            L V    ++ L
Sbjct: 369  LMVIDPLHVTL 379



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 4/54 (7%)

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            + W K+G+P+    R+          L I DL  EDSG Y C   N  G+ E +
Sbjct: 317  IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 366



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLL----HK-NRFTPIYDFGYVAMNFGWVYPEDSGEY 4046
            +F    A  G P   V W  + +P++    H+ N++T         MN       D G Y
Sbjct: 484  QFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVY 543

Query: 4047 LCRATNLYGMDETKAVIKTTGKPGI 4071
             C A NL G  E +A I   G P I
Sbjct: 544  RCTARNLVGSAEYQARINVRGPPSI 568



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 3710 GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA-LDIDYIYARDAGEY 3768
            G  ++  C V   GD  +RI W  +G+   +GS V T+    F++ L I  +  +  G Y
Sbjct: 670  GQLLYIPCVVSS-GDMPIRITWRKDGQVIISGSGV-TIESKEFMSSLQISSVSLKHNGNY 727

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
            TC A+N   + +   ++        V++     G+ G+
Sbjct: 728  TCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGK 765



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%)

Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHG 3639
            ++   D  +R+ W  +G+ +++GS V TI    F+  L+I  V  +  G YTC A+N   
Sbjct: 678  VVSSGDMPIRITWRKDGQVIISGSGV-TIESKEFMSSLQISSVSLKHNGNYTCIASN--A 734

Query: 3640 EATVSCKLQV 3649
             ATVS + Q+
Sbjct: 735  AATVSRERQL 744



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PPRFV Q  +Q  +   +     C +   G P  KV W  + K   +  ++ P+   G +
Sbjct: 749  PPRFVVQPNNQDGIYG-KAGVLNCSVD--GYPPPKVMWK-HAKGSGNPQQYHPVPLTGRI 804

Query: 4032 ------AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                  ++    V  ED G YLC+A+N  G D +K++  T   P ++
Sbjct: 805  QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 851



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 18/122 (14%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMP-MKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
            R N  E  +      A  ++I+     T P MKD+R+  N           VGDP   V+
Sbjct: 1333 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNS----------VGDPAPAVK 1382

Query: 1746 WLRNG----VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
            W ++     +P+        +H  G   L ++ V  EDSG YTC A N  G       L 
Sbjct: 1383 WTKDSEDSAIPVSMDGH-RLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLL 1439

Query: 1802 VQ 1803
            VQ
Sbjct: 1440 VQ 1441



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKDGR----PVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD    V+W KD      PV          N     L +++V   D+G+YTC A N  G
Sbjct: 1374 VGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1430

Query: 992  QATTSANLTIVTKKD 1006
              T   NL +    D
Sbjct: 1431 FDTIIVNLLVQVPPD 1445


>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhesion
            molecule DSCAML1 protein.
          Length = 2053

 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 89/365 (24%), Positives = 147/365 (40%), Gaps = 47/365 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAK 4493
            G P+P I+W ++  P+     +      TK I  L I  +  EDS  +     N  G+A+
Sbjct: 251  GYPIPAIRWLKDGRPLPADSRW------TKRITGLTISDLRTEDSGTYICEVTNTFGSAE 304

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  L+V          I P   TLT + +    G  V L   +TG+    + W +N + 
Sbjct: 305  ATGILMV----------IDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTEL 354

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            V PD    I       TLLI  A    SG Y+C A   A  A+  A  +++L        
Sbjct: 355  VLPDEAISIRGLSNE-TLLITSAQKSHSGAYQCFATRKAQTAQDFA--IIALE------- 404

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK-LIKPSKYFQMS 4672
                  +  P I+    +K+V  G+     C   G P PTV W   D+ +++   +    
Sbjct: 405  ------DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQ 458

Query: 4673 RTADEYT----LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             T  + T    + ++     D G Y+C A N  G     A++ V  P      P++  +R
Sbjct: 459  YTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP------PSIRAMR 512

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            +I    G+      ++      +I+W ++  L+P+    Q++ E N  + L       D 
Sbjct: 513  NITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDN-HRQVVFE-NGTLKLTDVQKGMDE 570

Query: 4789 GTFTC 4793
            G + C
Sbjct: 571  GEYLC 575



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 53/178 (29%), Positives = 79/178 (44%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C +TG P   + W+ N   +  D    I +    N  L+IT+   S SG   C
Sbjct: 329 GSTVILSCALTGSPEFTIRWYRNTELVLPD--EAISIRGLSNETLLITSAQKSHSGAYQC 386

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
            A  K+ +TA    +  +E      P+ V  FS   V  GE   L   A G P P +TW 
Sbjct: 387 FATRKA-QTAQDFAIIALEDG---TPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWA 442

Query: 526 KDGVPIIPNPELRIH----TDGGA-STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+ +   R +    +DG   S +++   +  D   Y+CTA+N+ GS   +AR+
Sbjct: 443 LDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARI 500



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 92/426 (21%), Positives = 162/426 (38%), Gaps = 37/426 (8%)

Query: 4393 KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK 4452
            KAQT +      ++   P I +   +   V   EQ        G P P + W  ++ PI 
Sbjct: 391  KAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQFSLMCAAKGAPPPTVTWALDDEPIV 449

Query: 4453 NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
                 + + ++      I  + V    +        GG  +C+A  +V     Q R  + 
Sbjct: 450  RDGSHRTNQYTMSDGTTISHMNVTGPQI------RDGGVYRCTARNLVGSAEYQARINVR 503

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
             P      +N+   +G+   ++ +V G     + W K+   + PD   +++ E+GT  L 
Sbjct: 504  GPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGTLKLT 562

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
             ++    D G+Y C               V+  P           A   PP +I+P +  
Sbjct: 563  DVQK-GMDEGEYLC--------------SVLIQPQLSISQSVHV-AVKVPP-LIQPFEFP 605

Query: 4633 IVAEGQAIEFSCKIVGKPLPT-VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              + GQ +   C +    +P  + W K  ++I       +       +L+IS    +  G
Sbjct: 606  PASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNG 665

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            +Y C+A N+A  V+   +L V  P +      + P     +Y G+       +     P 
Sbjct: 666  NYTCIASNAAATVSRERQLIVRVPPRF----VVQPNNQDGIY-GKAGVLNCSVDGYPPPK 720

Query: 4752 IQWLR-EGALIPE----TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG-QVETS 4805
            + W   +G+  P+     P    I    N+ LLI +  EED G + C+A+   G  +  S
Sbjct: 721  VMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKS 780

Query: 4806 AKLVVK 4811
              L VK
Sbjct: 781  MFLTVK 786



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 71/177 (40%), Gaps = 12/177 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHAL 450
           P+ V    ++ V  G+     C   G P P VTW ++D  I  D +H+      S    +
Sbjct: 408 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 467

Query: 451 MITNVT---LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
              NVT   + D GV  C ARN  G   +Q R+N      V  P  +     +    G  
Sbjct: 468 SHMNVTGPQIRDGGVYRCTARNLVGSAEYQARIN------VRGPPSIRAMRNITAVAGRD 521

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            ++N R +G P   I W KD + +  N    +  +G     D+   K  D   Y C+
Sbjct: 522 TLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDV--QKGMDEGEYLCS 576



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 67/273 (24%), Positives = 107/273 (39%), Gaps = 27/273 (9%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS-GKYECVAINS-AGEARCDAECV 4602
            V W K+   + P+ R  I    G Y   I +   +D+   Y C+  +  +GE R      
Sbjct: 159  VSWEKDTVSIIPENRFFITYHGGLY---ISDVQKEDALSTYRCITKHKYSGETRQSNGAR 215

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
            +S+          T  A + P I++    + V  G  +E  C   G P+P ++W K  + 
Sbjct: 216  LSV----------TDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRP 265

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
            +     +    T     L IS+   ED G Y C   N+ G       L V  P       
Sbjct: 266  LPADSRWTKRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHV---- 317

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG-NNAVLLIG 4781
             LTP + +    G        +T   + TI+W R   L+   PD  +   G +N  LLI 
Sbjct: 318  TLTP-KKLKTGIGSTVILSCALTGSPEFTIRWYRNTELV--LPDEAISIRGLSNETLLIT 374

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            +  +  +G + C AT  A   +  A + ++  T
Sbjct: 375  SAQKSHSGAYQCFATRKAQTAQDFAIIALEDGT 407



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 51/190 (26%), Positives = 80/190 (42%), Gaps = 16/190 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T  +CRV G PY  + W+  D  +  D NH+ +V E+G   L 
Sbjct: 505 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWY-KDALLLPD-NHRQVVFENGT--LK 560

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +T+V    D G   C           Q +L++ +   V    P  ++ F       G+ +
Sbjct: 561 LTDVQKGMDEGEYLC-------SVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLL 613

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +         P RITW+KDG  II    + I +    S+L I          Y C A N
Sbjct: 614 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 673

Query: 568 VAGSTATRAR 577
            A +T +R R
Sbjct: 674 -AAATVSRER 682



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 67/291 (23%), Positives = 102/291 (35%), Gaps = 36/291 (12%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I W ++   I +     I +    S L I  V ++ +  +  +A N   T      L+V 
Sbjct: 628  ITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVR 687

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK-----NGKKVQP 4556
                      VPP F +   N +   G+   L+  V G  P  V W       N ++  P
Sbjct: 688  ----------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHP 737

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
                  ++     +LLI     +D G Y C A N  G                D  K   
Sbjct: 738  VPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGT---------------DISKSMF 782

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS---KYFQMSR 4673
                 P  I       I  +G A E +C   G+    ++W KGD +I P    +Y   ++
Sbjct: 783  LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 842

Query: 4674 TADEYTLRISEAFPEDEGD---YKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
               +  +   +  P D GD   + C A NS G      +L V +P     L
Sbjct: 843  DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPEL 893



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 15/186 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTG--RPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           P  V+V +D+    G +  F C +    + Y  V  +  D       N   +    G   
Sbjct: 126 PYTVRV-EDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPENRFFITYHGG--- 181

Query: 450 LMITNVTLSDS-GVVTCVARNK-SGETAFQ--CRLNVIEKEQVVAPKFVERFSTLNVREG 505
           L I++V   D+     C+ ++K SGET      RL+V +  + + P  ++ F +  V  G
Sbjct: 182 LYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESI-PTILDGFHSQEVWAG 240

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             V L   A G P P I W KDG P+  +        G    L I   +  D+  Y C  
Sbjct: 241 HTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG----LTISDLRTEDSGTYICEV 296

Query: 566 QNVAGS 571
            N  GS
Sbjct: 297 TNTFGS 302



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 20/185 (10%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            S GQ+  Y   ++ +GD  + I W  +G+ I +   +       M  L+I       +G 
Sbjct: 608  SIGQLL-YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGN 666

Query: 3121 YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
            Y+C A+N    A +S + + + +     PRF     N +G+  G++    C+V     P 
Sbjct: 667  YTCIASN--AAATVSRERQLIVR---VPPRFVVQPNNQDGIY-GKAGVLNCSVDGYPPP- 719

Query: 3181 MKIEWYH---NGQPMRH-----STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             K+ W H   +G P ++     + RI+ + +   +   I +    D G Y+C+A N  G 
Sbjct: 720  -KVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL---IRHVLEEDIGYYLCQASNGVGT 775

Query: 3233 DFTRA 3237
            D +++
Sbjct: 776  DISKS 780



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 13/148 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W  +G+ + A  R  T    G+ + ++   +T DSGTY C  TN +G AE +  L  +
Sbjct: 257  IRWLKDGRPLPADSRW-TKRITGLTISDL---RTEDSGTYICEVTNTFGSAEATGILMVI 312

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            D      P   T     + LK G  +    +      P+  I WY N + +     I ++
Sbjct: 313  D------PLHVT--LTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI-SI 363

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229
                   L I   Q   SG Y C A  K
Sbjct: 364  RGLSNETLLITSAQKSHSGAYQCFATRK 391



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 58/275 (21%), Positives = 99/275 (36%), Gaps = 17/275 (6%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVSLLIKQIGPG--DEGEYTCTARNQY 152
           +G P P V+W     P+V    + + +Y    G     +   GP   D G Y CTARN  
Sbjct: 432 KGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLV 491

Query: 153 GEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
           G A     I   G                    +  +  G   Y+ +  +    +     
Sbjct: 492 GSAEYQARINVRGPPSIRAMRNITAVAGR-DTLINCRVIGYPYYSIKWYKDALLLP---- 546

Query: 213 TDHSSTDDFKVDTFEYRLLREVSFRESITK-RYVGESDVQISTEIDRSLG-PVSPPKIAQ 270
                 D+ +   FE   L+    ++ + +  Y+    +Q    I +S+   V  P + Q
Sbjct: 547 ------DNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQ 600

Query: 271 KPRNSKLQEGADAQFQVQLSGNPRP-RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQ 329
                    G        +S    P R+TW K+GQ +I+ +   I +    ++L++ +  
Sbjct: 601 PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVS 660

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
              +G+YT +A N    +     L V  P    VQ
Sbjct: 661 LKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQ 695



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPIIPNPELR 538
            IE       K +    T+     + V L   +VG P P + W KD     +P+  +    
Sbjct: 1282 IEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRL 1341

Query: 539  IHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            IHT+G   TL +   KA D+ +Y CTA N  G
Sbjct: 1342 IHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1370



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 4/72 (5%)

Query: 791 EAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNK 850
           E   T    P   + W KDGRP+ A SR T         L I  LR ED+G+Y     N 
Sbjct: 244 ELPCTASGYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNT 299

Query: 851 LGEAISTASIRV 862
            G A +T  + V
Sbjct: 300 FGSAEATGILMV 311



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 53/246 (21%), Positives = 103/246 (41%), Gaps = 16/246 (6%)

Query: 338 LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
           LL +N    +  +G L +    +   + +    +    Q    + + ++ K   P  ++ 
Sbjct: 544 LLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKV--PPLIQP 601

Query: 398 CQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            +    + G++    C V+    P  +TW   D Q+    +   + ++    +L I++V+
Sbjct: 602 FEFPPASIGQLLYIPCVVSSGDMPIRITWR-KDGQVIISGSGVTIESKEFMSSLQISSVS 660

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
           L  +G  TC+A N +   + + +L V      V P+FV + +  +   G+  VLN    G
Sbjct: 661 LKHNGNYTCIASNAAATVSRERQLIVR-----VPPRFVVQPNNQDGIYGKAGVLNCSVDG 715

Query: 517 TPTPRITWQK---DGVPIIPNP---ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P P++ W+     G P   +P     RI     +S L I      D  +Y C A N  G
Sbjct: 716 YPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL-IRHVLEEDIGYYLCQASNGVG 774

Query: 571 STATRA 576
           +  +++
Sbjct: 775 TDISKS 780



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 3/105 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P +   A  G  ++    +   GD  ++I W K+GQ I + S  T   +    SL
Sbjct: 596 PPLIQPFEFPPASIGQLLYIPCVVSS-GDMPIRITWRKDGQVIISGSGVTIESKEFMSSL 654

Query: 697 DMLSLNIQDSGEYTCRA--VSATGVAETKAVLHVTPRATIERTSQ 739
            + S++++ +G YTC A   +AT   E + ++ V PR  ++  +Q
Sbjct: 655 QISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQ 699



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLKDGRP+ A SR T         LTI  +   D+G Y C   N  G A  +  L ++
Sbjct: 257  IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 312



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 49/189 (25%), Positives = 72/189 (38%), Gaps = 14/189 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI----LVNESGN 447
           P+FV    ++D   GK    +C V G P P+V W            H +     +    N
Sbjct: 690 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 749

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            +L+I +V   D G   C A N  G    +     ++    +        +T    +G  
Sbjct: 750 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVK----IPAMITSHPNTTIAIKGHA 805

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELR--IHT-DGG---ASTLDIPRAKASDAAWY 561
             LN  A G     I W+K    I P+  +R  I T D G    STL +  A   D+ ++
Sbjct: 806 KELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFF 865

Query: 562 QCTAQNVAG 570
            C A N  G
Sbjct: 866 SCHAINSYG 874



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/81 (27%), Positives = 38/81 (46%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD  +R+ W KDG+ + + S +T        +L I SV++   G+YTC A NA    +  
Sbjct: 622  GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRE 681

Query: 997  ANLTIVTKKDIIAESQHPGGL 1017
              L +      + +  +  G+
Sbjct: 682  RQLIVRVPPRFVVQPNNQDGI 702



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
            EV  GH V L  T +    P +R  W  +GRP+    R+ T    G    D+     ED+
Sbjct: 236  EVWAGHTVELPCTASGYPIPAIR--WLKDGRPLPADSRW-TKRITGLTISDLR---TEDS 289

Query: 2048 GTYMCKATNAVGEAVTTSSVKV 2069
            GTY+C+ TN  G A  T  + V
Sbjct: 290  GTYICEVTNTFGSAEATGILMV 311



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 17/162 (10%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L+IR V  ED   +   A N  GT   S ++ +  K        +P   T        
Sbjct: 750  SSLLIRHVLEEDIGYYLCQASNGVGT-DISKSMFLTVK--------IPAMITSHPNTTIA 800

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD--IRNKILEED-GTYTLLILEAYPQDSG 4582
              G    L+    G +PI + W K    + PD  +R  I  +D G   +  L+  P D G
Sbjct: 801  IKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRG 860

Query: 4583 K---YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
                + C AINS GE R   +  V  P   D P+ + +   A
Sbjct: 861  DSVFFSCHAINSYGEDRGLIQLTVQEP--PDPPELEIREVKA 900



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 6/76 (7%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G  +   C    S  P   I W  + +PLP+ +R+          L I+    EDSG Y 
Sbjct: 240  GHTVELPCTA--SGYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYI 293

Query: 2848 CKATNSKGSATTSGSL 2863
            C+ TN+ GSA  +G L
Sbjct: 294  CEVTNTFGSAEATGIL 309



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            + W  + +PL + SR+T+        L I     EDSGTY C   N  G A  +GI +V
Sbjct: 257  IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMV 311



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   I WLK+G+ + A SR+T         L +  L  +DSG Y C   +  G AE  
Sbjct: 251 GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 306

Query: 724 AVLHV 728
            +L V
Sbjct: 307 GILMV 311



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 9/110 (8%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV  PP+F+ Q  +      +     C V+    PK  + W ++ K   +  +Y  V   
Sbjct: 685  IVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPK--VMW-KHAKGSGNPQQYHPVPLT 741

Query: 3885 GFV------SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            G +      SL I +V  ED G Y+C+A N  G D +K+     K+P +I
Sbjct: 742  GRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 791



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/135 (24%), Positives = 51/135 (37%), Gaps = 13/135 (9%)

Query: 1276 VTDTQNEQAIEQIQLL-----EDAARRTKQVREDIT--VMQAPQFSRALHNIETVEGTNV 1328
            ++D Q E A+   + +         R++   R  +T      P      H+ E   G  V
Sbjct: 184  ISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTV 243

Query: 1329 HLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT 1388
             L C     G     + W  +G+P+    R+          L +  +  EDSG Y C+ T
Sbjct: 244  ELPCTAS--GYPIPAIRWLKDGRPLPADSRWTKRI----TGLTISDLRTEDSGTYICEVT 297

Query: 1389 NQLGEAVTSCALRVI 1403
            N  G A  +  L VI
Sbjct: 298  NTFGSAEATGILMVI 312



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++G P+ A +R T         L +  +  EDSGTY C   N  G A  +
Sbjct: 251  GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEAT 306

Query: 1798 STLFV 1802
              L V
Sbjct: 307  GILMV 311



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            I W K+G  L   +R        +  L+I+ LR +DSG Y C+ TN  G A +T  + + 
Sbjct: 257  IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 312

Query: 2736 D 2736
            D
Sbjct: 313  D 313



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 4/135 (2%)

Query: 3800 PQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            PQ   G   +   R  +  A  +  I    P  I  +++ T          CRV     P
Sbjct: 475  PQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGY--P 532

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               I+WY++  LLP  HR + V++ G + L  +     D GEY+C  +       +++  
Sbjct: 533  YYSIKWYKDALLLPDNHR-QVVFENGTLKLTDVQ-KGMDEGEYLCSVLIQPQLSISQSVH 590

Query: 3920 SCKKLPDIILQNQVP 3934
               K+P +I   + P
Sbjct: 591  VAVKVPPLIQPFEFP 605



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/174 (23%), Positives = 64/174 (36%), Gaps = 13/174 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W+ N + +     I ++       L I   + + SG Y C AT K   A+ 
Sbjct: 339  TGSPEFTIRWYRNTELVLPDEAI-SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 397

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-- 3192
               +   D +      F+  + N      G+     C       P   + W  + +P+  
Sbjct: 398  FAIIALEDGTPRIVSSFSEKVVN-----PGEQFSLMCAAKGAPPPT--VTWALDDEPIVR 450

Query: 3193 --RHSTRIKTVSDFGFVV-LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
               H T   T+SD   +  +++   Q  D G Y C A N  G    +A IN  G
Sbjct: 451  DGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG 504



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 4436 GEPLPLIKWYREN----FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
            G+P P +KW +++     P+       IHT  T   L++R V  EDS  +   A N GG 
Sbjct: 1315 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT---LLLRAVKAEDSGYYTCTATNTGGF 1371

Query: 4492 AKCSANLVVEEKRRQGR 4508
                 NL+V+    Q R
Sbjct: 1372 DTIIVNLLVQVPPDQPR 1388



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 5/101 (4%)

Query: 3441 EARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNN 3500
            E   T +  P   + W  +G+ L A SR+          L IS    EDSG Y+C   N 
Sbjct: 244  ELPCTASGYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNT 299

Query: 3501 YGEAVTTASMKVQGKRNIIL-ESQLPKGMEGTIDKIAALEG 3540
            +G A  T  + V    ++ L   +L  G+  T+    AL G
Sbjct: 300  FGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTG 340



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/124 (22%), Positives = 47/124 (37%), Gaps = 1/124 (0%)

Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
           S E    L  + P  +   P+  K   G+       L+G+P   + W++N + ++     
Sbjct: 302 SAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI 361

Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYIT 372
            I    N T L + + QKS SG Y   A            +A+E  T   V     + + 
Sbjct: 362 SIRGLSNETLL-ITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVN 420

Query: 373 DTQQ 376
             +Q
Sbjct: 421 PGEQ 424



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/104 (32%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG--DKLIKPSKY-FQMSRT 4674
            A  AP +II           + +   C  VG P P V+W K   D  I  S    ++  T
Sbjct: 1285 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHT 1344

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQ 4717
                 LR  +A  ED G Y C A N+ G  T+   L V   PDQ
Sbjct: 1345 NGTLLLRAVKA--EDSGYYTCTATNTGGFDTIIVNLLVQVPPDQ 1386



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 282  DAQFQVQLSGNPRPRVTWFKNGQRL---INSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            D +      G+P P V W K+ +     ++ + H +I  H + TL +R  +  DSG+YT 
Sbjct: 1306 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLI--HTNGTLLLRAVKAEDSGYYTC 1363

Query: 339  LAENPNGCIVTSGYLAVESPTE 360
             A N  G       L V+ P +
Sbjct: 1364 TATNTGGFDTIIVNLLVQVPPD 1385



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 9/90 (10%)

Query: 1471 VTDSNLKVEWFKNGQ----PVTI-GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525
            V D    V+W K+ +    PV++ GHR   IH  G + L  +   AEDSG YTC A N  
Sbjct: 1314 VGDPAPAVKWTKDSEDSAIPVSMDGHRL--IHTNGTLLLRAVK--AEDSGYYTCTATNTG 1369

Query: 1526 GTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555
            G D +   L  +   D  R T ++     I
Sbjct: 1370 GFDTIIVNLLVQVPPDQPRLTVSKTSASSI 1399



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 16/174 (9%)

Query: 3063 GQIAHYEASLIPTGDQSMV--IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            G +A ++  LIP+  Q  V  + W  +  +I   +R    Y  G+ + ++   K     T
Sbjct: 139  GNVAVFKC-LIPSSVQEYVSVVSWEKDTVSIIPENRFFITYHGGLYISDV--QKEDALST 195

Query: 3121 YSCRATNKW-GQAEIS--VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            Y C   +K+ G+   S   +L   D ++   P       + E +  G +    CT     
Sbjct: 196  YRCITKHKYSGETRQSNGARLSVTDPAESI-PTILDGFHSQE-VWAGHTVELPCTASGYP 253

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             P   I W  +G+P+   +R  T    G  + D+   +  DSG Y+C   N +G
Sbjct: 254  IP--AIRWLKDGRPLPADSRW-TKRITGLTISDL---RTEDSGTYICEVTNTFG 301



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-- 3870
            RG  S+    EP    P K I+   + T    + VR  C      DP   ++W ++ +  
Sbjct: 1273 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCN--SVGDPAPAVKWTKDSEDS 1330

Query: 3871 LLP-SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             +P S   +R ++  G  +L +  V AEDSG Y C A N  G D     +  +  PD
Sbjct: 1331 AIPVSMDGHRLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPD 1385



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 6/77 (7%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            +V  G  V   C     G P   I W  +GRP    SR  T    G   L I  +   D+
Sbjct: 236  EVWAGHTVELPCTAS--GYPIPAIRWLKDGRPLPADSR-WTKRITG---LTISDLRTEDS 289

Query: 3766 GEYTCRATNKWGSATTT 3782
            G Y C  TN +GSA  T
Sbjct: 290  GTYICEVTNTFGSAEAT 306



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G T    C     G P   + W ++ + +   SR TK        +TIS +R ED G Y+
Sbjct: 240  GHTVELPCTAS--GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYI 293

Query: 2451 CRASNLLG 2458
            C  +N  G
Sbjct: 294  CEVTNTFG 301



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 5/120 (4%)

Query: 240 ITK-RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT 298
           ITK +Y GE+       +  +    S P I     + ++  G   +     SG P P + 
Sbjct: 199 ITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIR 258

Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           W K+G+ L   ++     T   T L + + +  DSG Y     N  G    +G L V  P
Sbjct: 259 WLKDGRPLPADSR----WTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 314



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +    C    YP P +R  W  +G+ L +  R+ T    G    D+ T   EDSG Y 
Sbjct: 240  GHTVELPCTASGYPIPAIR--WLKDGRPLPADSRW-TKRITGLTISDLRT---EDSGTYI 293

Query: 1919 CKAINNLGQA 1928
            C+  N  G A
Sbjct: 294  CEVTNTFGSA 303



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 9/103 (8%)

Query: 53  ESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL 112
           +S+G R  +T   P E  P I +       +A G   +      G P P + W +   PL
Sbjct: 210 QSNGARLSVTD--PAESIPTILDGFHSQEVWA-GHTVELPCTASGYPIPAIRWLKDGRPL 266

Query: 113 VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
              ++++ R    TG   L I  +   D G Y C   N +G A
Sbjct: 267 PADSRWTKRI---TG---LTISDLRTEDSGTYICEVTNTFGSA 303



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 6/82 (7%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  +    S  V     V   C       P +R  W ++G+ LP+  R+          L
Sbjct: 226  PTILDGFHSQEVWAGHTVELPCTASGYPIPAIR--WLKDGRPLPADSRWTK----RITGL 279

Query: 3890 DILYVYAEDSGEYICRAVNDFG 3911
             I  +  EDSG YIC   N FG
Sbjct: 280  TISDLRTEDSGTYICEVTNTFG 301



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
            G P   + W  +G+PL   +R+T         +    +  EDSG Y+C  TN +G  E  
Sbjct: 251  GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 306

Query: 4061 AVI 4063
             ++
Sbjct: 307  GIL 309



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W  +G+ + A  R+ T    G    D+     EDSGTY+C+ TN  G A  T  
Sbjct: 253  PIPAIRWLKDGRPLPADSRW-TKRITGLTISDLR---TEDSGTYICEVTNTFGSAEATGI 308

Query: 2199 LKVAGHRNIIL 2209
            L V    ++ L
Sbjct: 309  LMVIDPLHVTL 319



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 41/161 (25%), Positives = 67/161 (41%), Gaps = 20/161 (12%)

Query: 4644 CKIVGKPLPTVQWY--KGDKL--IKPSKYFQMSRTADEYTLRIS--EAFPEDEGDYKCVA 4697
            C   G P   ++WY   GD +  +   ++   + T   Y    S   +F  D  DY C A
Sbjct: 47   CPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDN-DYFCTA 105

Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK---PTIQW 4754
             N+AG++  +  ++V    +    P    + D     G  A FK  I S ++     + W
Sbjct: 106  ENAAGKIR-SPNIRVKAVFRE---PYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSW 161

Query: 4755 LREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDT-GTFTC 4793
             ++  ++IPE   F   H G    L I +  +ED   T+ C
Sbjct: 162  EKDTVSIIPENRFFITYHGG----LYISDVQKEDALSTYRC 198



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 4/54 (7%)

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            + W K+G+P+    R+          L I DL  EDSG Y C   N  G+ E +
Sbjct: 257  IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 306



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLL----HK-NRFTPIYDFGYVAMNFGWVYPEDSGEY 4046
            +F    A  G P   V W  + +P++    H+ N++T         MN       D G Y
Sbjct: 424  QFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVY 483

Query: 4047 LCRATNLYGMDETKAVIKTTGKPGI 4071
             C A NL G  E +A I   G P I
Sbjct: 484  RCTARNLVGSAEYQARINVRGPPSI 508



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 3710 GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA-LDIDYIYARDAGEY 3768
            G  ++  C V   GD  +RI W  +G+   +GS V T+    F++ L I  +  +  G Y
Sbjct: 610  GQLLYIPCVVSS-GDMPIRITWRKDGQVIISGSGV-TIESKEFMSSLQISSVSLKHNGNY 667

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
            TC A+N   + +   ++        V++     G+ G+
Sbjct: 668  TCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGK 705



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%)

Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHG 3639
            ++   D  +R+ W  +G+ +++GS V TI    F+  L+I  V  +  G YTC A+N   
Sbjct: 618  VVSSGDMPIRITWRKDGQVIISGSGV-TIESKEFMSSLQISSVSLKHNGNYTCIASN--A 674

Query: 3640 EATVSCKLQV 3649
             ATVS + Q+
Sbjct: 675  AATVSRERQL 684



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PPRFV Q  +Q  +   +     C +   G P  KV W  + K   +  ++ P+   G +
Sbjct: 689  PPRFVVQPNNQDGIYG-KAGVLNCSVD--GYPPPKVMWK-HAKGSGNPQQYHPVPLTGRI 744

Query: 4032 ------AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                  ++    V  ED G YLC+A+N  G D +K++  T   P ++
Sbjct: 745  QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 791



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 18/122 (14%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMP-MKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
            R N  E  +      A  ++I+     T P MKD+R+  N           VGDP   V+
Sbjct: 1273 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNS----------VGDPAPAVK 1322

Query: 1746 WLRNG----VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
            W ++     +P+        +H  G   L ++ V  EDSG YTC A N  G       L 
Sbjct: 1323 WTKDSEDSAIPVSMDGH-RLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLL 1379

Query: 1802 VQ 1803
            VQ
Sbjct: 1380 VQ 1381



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKDGR----PVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD    V+W KD      PV          N     L +++V   D+G+YTC A N  G
Sbjct: 1314 VGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1370

Query: 992  QATTSANLTIVTKKD 1006
              T   NL +    D
Sbjct: 1371 FDTIIVNLLVQVPPD 1385


>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
          Length = 2092

 Score = 89.4 bits (212), Expect = 3e-16
 Identities = 89/365 (24%), Positives = 147/365 (40%), Gaps = 47/365 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAK 4493
            G P+P I+W ++  P+     +      TK I  L I  +  EDS  +     N  G+A+
Sbjct: 290  GYPIPAIRWLKDGRPLPADSRW------TKRITGLTISDLRTEDSGTYICEVTNTFGSAE 343

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             +  L+V          I P   TLT + +    G  V L   +TG+    + W +N + 
Sbjct: 344  ATGILMV----------IDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTEL 393

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            V PD    I       TLLI  A    SG Y+C A   A  A+  A  +++L        
Sbjct: 394  VLPDEAISIRGLSNE-TLLITSAQKSHSGAYQCFATRKAQTAQDFA--IIALE------- 443

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK-LIKPSKYFQMS 4672
                  +  P I+    +K+V  G+     C   G P PTV W   D+ +++   +    
Sbjct: 444  ------DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQ 497

Query: 4673 RTADEYT----LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
             T  + T    + ++     D G Y+C A N  G     A++ V  P      P++  +R
Sbjct: 498  YTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP------PSIRAMR 551

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            +I    G+      ++      +I+W ++  L+P+    Q++ E N  + L       D 
Sbjct: 552  NITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDN-HRQVVFE-NGTLKLTDVQKGMDE 609

Query: 4789 GTFTC 4793
            G + C
Sbjct: 610  GEYLC 614



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 53/178 (29%), Positives = 79/178 (44%), Gaps = 11/178 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C +TG P   + W+ N   +  D    I +    N  L+IT+   S SG   C
Sbjct: 368 GSTVILSCALTGSPEFTIRWYRNTELVLPD--EAISIRGLSNETLLITSAQKSHSGAYQC 425

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
            A  K+ +TA    +  +E      P+ V  FS   V  GE   L   A G P P +TW 
Sbjct: 426 FATRKA-QTAQDFAIIALEDG---TPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWA 481

Query: 526 KDGVPIIPNPELRIH----TDGGA-STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  PI+ +   R +    +DG   S +++   +  D   Y+CTA+N+ GS   +AR+
Sbjct: 482 LDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARI 539



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 92/426 (21%), Positives = 162/426 (38%), Gaps = 37/426 (8%)

Query: 4393 KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK 4452
            KAQT +      ++   P I +   +   V   EQ        G P P + W  ++ PI 
Sbjct: 430  KAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQFSLMCAAKGAPPPTVTWALDDEPIV 488

Query: 4453 NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
                 + + ++      I  + V    +        GG  +C+A  +V     Q R  + 
Sbjct: 489  RDGSHRTNQYTMSDGTTISHMNVTGPQI------RDGGVYRCTARNLVGSAEYQARINVR 542

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
             P      +N+   +G+   ++ +V G     + W K+   + PD   +++ E+GT  L 
Sbjct: 543  GPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGTLKLT 601

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
             ++    D G+Y C               V+  P           A   PP +I+P +  
Sbjct: 602  DVQK-GMDEGEYLC--------------SVLIQPQLSISQSVHV-AVKVPP-LIQPFEFP 644

Query: 4633 IVAEGQAIEFSCKIVGKPLPT-VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
              + GQ +   C +    +P  + W K  ++I       +       +L+IS    +  G
Sbjct: 645  PASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNG 704

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            +Y C+A N+A  V+   +L V  P +      + P     +Y G+       +     P 
Sbjct: 705  NYTCIASNAAATVSRERQLIVRVPPRF----VVQPNNQDGIY-GKAGVLNCSVDGYPPPK 759

Query: 4752 IQWLR-EGALIPE----TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG-QVETS 4805
            + W   +G+  P+     P    I    N+ LLI +  EED G + C+A+   G  +  S
Sbjct: 760  VMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKS 819

Query: 4806 AKLVVK 4811
              L VK
Sbjct: 820  MFLTVK 825



 Score = 70.1 bits (164), Expect = 2e-10
 Identities = 48/177 (27%), Positives = 71/177 (40%), Gaps = 12/177 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNESGNHAL 450
           P+ V    ++ V  G+     C   G P P VTW ++D  I  D +H+      S    +
Sbjct: 447 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 506

Query: 451 MITNVT---LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
              NVT   + D GV  C ARN  G   +Q R+N      V  P  +     +    G  
Sbjct: 507 SHMNVTGPQIRDGGVYRCTARNLVGSAEYQARIN------VRGPPSIRAMRNITAVAGRD 560

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            ++N R +G P   I W KD + +  N    +  +G     D+   K  D   Y C+
Sbjct: 561 TLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDV--QKGMDEGEYLCS 615



 Score = 62.5 bits (145), Expect = 4e-08
 Identities = 67/273 (24%), Positives = 107/273 (39%), Gaps = 27/273 (9%)

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS-GKYECVAINS-AGEARCDAECV 4602
            V W K+   + P+ R  I    G Y   I +   +D+   Y C+  +  +GE R      
Sbjct: 198  VSWEKDTVSIIPENRFFITYHGGLY---ISDVQKEDALSTYRCITKHKYSGETRQSNGAR 254

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
            +S+          T  A + P I++    + V  G  +E  C   G P+P ++W K  + 
Sbjct: 255  LSV----------TDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRP 304

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
            +     +    T     L IS+   ED G Y C   N+ G       L V  P       
Sbjct: 305  LPADSRWTKRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHV---- 356

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG-NNAVLLIG 4781
             LTP + +    G        +T   + TI+W R   L+   PD  +   G +N  LLI 
Sbjct: 357  TLTP-KKLKTGIGSTVILSCALTGSPEFTIRWYRNTELV--LPDEAISIRGLSNETLLIT 413

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            +  +  +G + C AT  A   +  A + ++  T
Sbjct: 414  SAQKSHSGAYQCFATRKAQTAQDFAIIALEDGT 446



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 51/190 (26%), Positives = 80/190 (42%), Gaps = 16/190 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  ++  ++     G+ T  +CRV G PY  + W+  D  +  D NH+ +V E+G   L 
Sbjct: 544 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWY-KDALLLPD-NHRQVVFENGT--LK 599

Query: 452 ITNVTLS-DSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           +T+V    D G   C           Q +L++ +   V    P  ++ F       G+ +
Sbjct: 600 LTDVQKGMDEGEYLC-------SVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLL 652

Query: 509 VLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +         P RITW+KDG  II    + I +    S+L I          Y C A N
Sbjct: 653 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 712

Query: 568 VAGSTATRAR 577
            A +T +R R
Sbjct: 713 -AAATVSRER 721



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 67/291 (23%), Positives = 102/291 (35%), Gaps = 36/291 (12%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            I W ++   I +     I +    S L I  V ++ +  +  +A N   T      L+V 
Sbjct: 667  ITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVR 726

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK-----NGKKVQP 4556
                      VPP F +   N +   G+   L+  V G  P  V W       N ++  P
Sbjct: 727  ----------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHP 776

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
                  ++     +LLI     +D G Y C A N  G                D  K   
Sbjct: 777  VPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGT---------------DISKSMF 821

Query: 4617 KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS---KYFQMSR 4673
                 P  I       I  +G A E +C   G+    ++W KGD +I P    +Y   ++
Sbjct: 822  LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 881

Query: 4674 TADEYTLRISEAFPEDEGD---YKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
               +  +   +  P D GD   + C A NS G      +L V +P     L
Sbjct: 882  DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPEL 932



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 15/186 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTG--RPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           P  V+V +D+    G +  F C +    + Y  V  +  D       N   +    G   
Sbjct: 165 PYTVRV-EDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPENRFFITYHGG--- 220

Query: 450 LMITNVTLSDS-GVVTCVARNK-SGETAFQ--CRLNVIEKEQVVAPKFVERFSTLNVREG 505
           L I++V   D+     C+ ++K SGET      RL+V +  + + P  ++ F +  V  G
Sbjct: 221 LYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESI-PTILDGFHSQEVWAG 279

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             V L   A G P P I W KDG P+  +        G    L I   +  D+  Y C  
Sbjct: 280 HTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG----LTISDLRTEDSGTYICEV 335

Query: 566 QNVAGS 571
            N  GS
Sbjct: 336 TNTFGS 341



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 20/185 (10%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            S GQ+  Y   ++ +GD  + I W  +G+ I +   +       M  L+I       +G 
Sbjct: 647  SIGQLL-YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGN 705

Query: 3121 YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
            Y+C A+N    A +S + + + +     PRF     N +G+  G++    C+V     P 
Sbjct: 706  YTCIASN--AAATVSRERQLIVR---VPPRFVVQPNNQDGIY-GKAGVLNCSVDGYPPP- 758

Query: 3181 MKIEWYH---NGQPMRH-----STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             K+ W H   +G P ++     + RI+ + +   +   I +    D G Y+C+A N  G 
Sbjct: 759  -KVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL---IRHVLEEDIGYYLCQASNGVGT 814

Query: 3233 DFTRA 3237
            D +++
Sbjct: 815  DISKS 819



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 13/148 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W  +G+ + A  R  T    G+ + ++   +T DSGTY C  TN +G AE +  L  +
Sbjct: 296  IRWLKDGRPLPADSRW-TKRITGLTISDL---RTEDSGTYICEVTNTFGSAEATGILMVI 351

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            D      P   T     + LK G  +    +      P+  I WY N + +     I ++
Sbjct: 352  D------PLHVT--LTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI-SI 402

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229
                   L I   Q   SG Y C A  K
Sbjct: 403  RGLSNETLLITSAQKSHSGAYQCFATRK 430



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 58/275 (21%), Positives = 99/275 (36%), Gaps = 17/275 (6%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKY-SMRYNEQTGDVSLLIKQIGPG--DEGEYTCTARNQY 152
           +G P P V+W     P+V    + + +Y    G     +   GP   D G Y CTARN  
Sbjct: 471 KGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLV 530

Query: 153 GEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
           G A     I   G                    +  +  G   Y+ +  +    +     
Sbjct: 531 GSAEYQARINVRGPPSIRAMRNITAVAGR-DTLINCRVIGYPYYSIKWYKDALLLP---- 585

Query: 213 TDHSSTDDFKVDTFEYRLLREVSFRESITK-RYVGESDVQISTEIDRSLG-PVSPPKIAQ 270
                 D+ +   FE   L+    ++ + +  Y+    +Q    I +S+   V  P + Q
Sbjct: 586 ------DNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQ 639

Query: 271 KPRNSKLQEGADAQFQVQLSGNPRP-RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQ 329
                    G        +S    P R+TW K+GQ +I+ +   I +    ++L++ +  
Sbjct: 640 PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVS 699

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
              +G+YT +A N    +     L V  P    VQ
Sbjct: 700 LKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQ 734



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD----GVPIIPNPELR 538
            IE       K +    T+     + V L   +VG P P + W KD     +P+  +    
Sbjct: 1321 IEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRL 1380

Query: 539  IHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            IHT+G   TL +   KA D+ +Y CTA N  G
Sbjct: 1381 IHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1409



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 4/72 (5%)

Query: 791 EAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNK 850
           E   T    P   + W KDGRP+ A SR T         L I  LR ED+G+Y     N 
Sbjct: 283 ELPCTASGYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNT 338

Query: 851 LGEAISTASIRV 862
            G A +T  + V
Sbjct: 339 FGSAEATGILMV 350



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 53/246 (21%), Positives = 103/246 (41%), Gaps = 16/246 (6%)

Query: 338 LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
           LL +N    +  +G L +    +   + +    +    Q    + + ++ K   P  ++ 
Sbjct: 583 LLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKV--PPLIQP 640

Query: 398 CQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            +    + G++    C V+    P  +TW   D Q+    +   + ++    +L I++V+
Sbjct: 641 FEFPPASIGQLLYIPCVVSSGDMPIRITWR-KDGQVIISGSGVTIESKEFMSSLQISSVS 699

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
           L  +G  TC+A N +   + + +L V      V P+FV + +  +   G+  VLN    G
Sbjct: 700 LKHNGNYTCIASNAAATVSRERQLIVR-----VPPRFVVQPNNQDGIYGKAGVLNCSVDG 754

Query: 517 TPTPRITWQK---DGVPIIPNP---ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            P P++ W+     G P   +P     RI     +S L I      D  +Y C A N  G
Sbjct: 755 YPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLL-IRHVLEEDIGYYLCQASNGVG 813

Query: 571 STATRA 576
           +  +++
Sbjct: 814 TDISKS 819



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 3/105 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P  I P +   A  G  ++    +   GD  ++I W K+GQ I + S  T   +    SL
Sbjct: 635 PPLIQPFEFPPASIGQLLYIPCVVSS-GDMPIRITWRKDGQVIISGSGVTIESKEFMSSL 693

Query: 697 DMLSLNIQDSGEYTCRA--VSATGVAETKAVLHVTPRATIERTSQ 739
            + S++++ +G YTC A   +AT   E + ++ V PR  ++  +Q
Sbjct: 694 QISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQ 738



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + WLKDGRP+ A SR T         LTI  +   D+G Y C   N  G A  +  L ++
Sbjct: 296  IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 351



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 49/189 (25%), Positives = 72/189 (38%), Gaps = 14/189 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI----LVNESGN 447
           P+FV    ++D   GK    +C V G P P+V W            H +     +    N
Sbjct: 729 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 788

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
            +L+I +V   D G   C A N  G    +     ++    +        +T    +G  
Sbjct: 789 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVK----IPAMITSHPNTTIAIKGHA 844

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELR--IHT-DGG---ASTLDIPRAKASDAAWY 561
             LN  A G     I W+K    I P+  +R  I T D G    STL +  A   D+ ++
Sbjct: 845 KELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFF 904

Query: 562 QCTAQNVAG 570
            C A N  G
Sbjct: 905 SCHAINSYG 913



 Score = 43.6 bits (98), Expect = 0.018
 Identities = 22/81 (27%), Positives = 38/81 (46%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD  +R+ W KDG+ + + S +T        +L I SV++   G+YTC A NA    +  
Sbjct: 661  GDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRE 720

Query: 997  ANLTIVTKKDIIAESQHPGGL 1017
              L +      + +  +  G+
Sbjct: 721  RQLIVRVPPRFVVQPNNQDGI 741



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
            EV  GH V L  T +    P +R  W  +GRP+    R+ T    G    D+     ED+
Sbjct: 275  EVWAGHTVELPCTASGYPIPAIR--WLKDGRPLPADSRW-TKRITGLTISDLR---TEDS 328

Query: 2048 GTYMCKATNAVGEAVTTSSVKV 2069
            GTY+C+ TN  G A  T  + V
Sbjct: 329  GTYICEVTNTFGSAEATGILMV 350



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 17/162 (10%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            S L+IR V  ED   +   A N  GT   S ++ +  K        +P   T        
Sbjct: 789  SSLLIRHVLEEDIGYYLCQASNGVGT-DISKSMFLTVK--------IPAMITSHPNTTIA 839

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD--IRNKILEED-GTYTLLILEAYPQDSG 4582
              G    L+    G +PI + W K    + PD  +R  I  +D G   +  L+  P D G
Sbjct: 840  IKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRG 899

Query: 4583 K---YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
                + C AINS GE R   +  V  P   D P+ + +   A
Sbjct: 900  DSVFFSCHAINSYGEDRGLIQLTVQEP--PDPPELEIREVKA 939



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 6/76 (7%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G  +   C    S  P   I W  + +PLP+ +R+          L I+    EDSG Y 
Sbjct: 279  GHTVELPCTA--SGYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYI 332

Query: 2848 CKATNSKGSATTSGSL 2863
            C+ TN+ GSA  +G L
Sbjct: 333  CEVTNTFGSAEATGIL 348



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            + W  + +PL + SR+T+        L I     EDSGTY C   N  G A  +GI +V
Sbjct: 296  IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMV 350



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   I WLK+G+ + A SR+T         L +  L  +DSG Y C   +  G AE  
Sbjct: 290 GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 345

Query: 724 AVLHV 728
            +L V
Sbjct: 346 GILMV 350



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 9/110 (8%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV  PP+F+ Q  +      +     C V+    PK  + W ++ K   +  +Y  V   
Sbjct: 724  IVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPK--VMW-KHAKGSGNPQQYHPVPLT 780

Query: 3885 GFV------SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            G +      SL I +V  ED G Y+C+A N  G D +K+     K+P +I
Sbjct: 781  GRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 830



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/135 (24%), Positives = 51/135 (37%), Gaps = 13/135 (9%)

Query: 1276 VTDTQNEQAIEQIQLL-----EDAARRTKQVREDIT--VMQAPQFSRALHNIETVEGTNV 1328
            ++D Q E A+   + +         R++   R  +T      P      H+ E   G  V
Sbjct: 223  ISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTV 282

Query: 1329 HLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQAT 1388
             L C     G     + W  +G+P+    R+          L +  +  EDSG Y C+ T
Sbjct: 283  ELPCTAS--GYPIPAIRWLKDGRPLPADSRWTKRI----TGLTISDLRTEDSGTYICEVT 336

Query: 1389 NQLGEAVTSCALRVI 1403
            N  G A  +  L VI
Sbjct: 337  NTFGSAEATGILMVI 351



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + WL++G P+ A +R T         L +  +  EDSGTY C   N  G A  +
Sbjct: 290  GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEAT 345

Query: 1798 STLFV 1802
              L V
Sbjct: 346  GILMV 350



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            I W K+G  L   +R        +  L+I+ LR +DSG Y C+ TN  G A +T  + + 
Sbjct: 296  IRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 351

Query: 2736 D 2736
            D
Sbjct: 352  D 352



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 4/135 (2%)

Query: 3800 PQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            PQ   G   +   R  +  A  +  I    P  I  +++ T          CRV     P
Sbjct: 514  PQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGY--P 571

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               I+WY++  LLP  HR + V++ G + L  +     D GEY+C  +       +++  
Sbjct: 572  YYSIKWYKDALLLPDNHR-QVVFENGTLKLTDVQ-KGMDEGEYLCSVLIQPQLSISQSVH 629

Query: 3920 SCKKLPDIILQNQVP 3934
               K+P +I   + P
Sbjct: 630  VAVKVPPLIQPFEFP 644



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/174 (23%), Positives = 64/174 (36%), Gaps = 13/174 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W+ N + +     I ++       L I   + + SG Y C AT K   A+ 
Sbjct: 378  TGSPEFTIRWYRNTELVLPDEAI-SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 436

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-- 3192
               +   D +      F+  + N      G+     C       P   + W  + +P+  
Sbjct: 437  FAIIALEDGTPRIVSSFSEKVVN-----PGEQFSLMCAAKGAPPPT--VTWALDDEPIVR 489

Query: 3193 --RHSTRIKTVSDFGFVV-LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
               H T   T+SD   +  +++   Q  D G Y C A N  G    +A IN  G
Sbjct: 490  DGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRG 543



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 4436 GEPLPLIKWYREN----FPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
            G+P P +KW +++     P+       IHT  T   L++R V  EDS  +   A N GG 
Sbjct: 1354 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT---LLLRAVKAEDSGYYTCTATNTGGF 1410

Query: 4492 AKCSANLVVEEKRRQGR 4508
                 NL+V+    Q R
Sbjct: 1411 DTIIVNLLVQVPPDQPR 1427



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 5/101 (4%)

Query: 3441 EARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNN 3500
            E   T +  P   + W  +G+ L A SR+          L IS    EDSG Y+C   N 
Sbjct: 283  ELPCTASGYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNT 338

Query: 3501 YGEAVTTASMKVQGKRNIIL-ESQLPKGMEGTIDKIAALEG 3540
            +G A  T  + V    ++ L   +L  G+  T+    AL G
Sbjct: 339  FGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTG 379



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 28/124 (22%), Positives = 47/124 (37%), Gaps = 1/124 (0%)

Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
           S E    L  + P  +   P+  K   G+       L+G+P   + W++N + ++     
Sbjct: 341 SAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI 400

Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYIT 372
            I    N T L + + QKS SG Y   A            +A+E  T   V     + + 
Sbjct: 401 SIRGLSNETLL-ITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVN 459

Query: 373 DTQQ 376
             +Q
Sbjct: 460 PGEQ 463



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 34/104 (32%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG--DKLIKPSKY-FQMSRT 4674
            A  AP +II           + +   C  VG P P V+W K   D  I  S    ++  T
Sbjct: 1324 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHT 1383

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQ 4717
                 LR  +A  ED G Y C A N+ G  T+   L V   PDQ
Sbjct: 1384 NGTLLLRAVKA--EDSGYYTCTATNTGGFDTIIVNLLVQVPPDQ 1425



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 282  DAQFQVQLSGNPRPRVTWFKNGQRL---INSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            D +      G+P P V W K+ +     ++ + H +I  H + TL +R  +  DSG+YT 
Sbjct: 1345 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLI--HTNGTLLLRAVKAEDSGYYTC 1402

Query: 339  LAENPNGCIVTSGYLAVESPTE 360
             A N  G       L V+ P +
Sbjct: 1403 TATNTGGFDTIIVNLLVQVPPD 1424



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 9/90 (10%)

Query: 1471 VTDSNLKVEWFKNGQ----PVTI-GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525
            V D    V+W K+ +    PV++ GHR   IH  G + L  +   AEDSG YTC A N  
Sbjct: 1353 VGDPAPAVKWTKDSEDSAIPVSMDGHRL--IHTNGTLLLRAVK--AEDSGYYTCTATNTG 1408

Query: 1526 GTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555
            G D +   L  +   D  R T ++     I
Sbjct: 1409 GFDTIIVNLLVQVPPDQPRLTVSKTSASSI 1438



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 16/174 (9%)

Query: 3063 GQIAHYEASLIPTGDQSMV--IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            G +A ++  LIP+  Q  V  + W  +  +I   +R    Y  G+ + ++   K     T
Sbjct: 178  GNVAVFKC-LIPSSVQEYVSVVSWEKDTVSIIPENRFFITYHGGLYISDV--QKEDALST 234

Query: 3121 YSCRATNKW-GQAEIS--VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
            Y C   +K+ G+   S   +L   D ++   P       + E +  G +    CT     
Sbjct: 235  YRCITKHKYSGETRQSNGARLSVTDPAESI-PTILDGFHSQE-VWAGHTVELPCTASGYP 292

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             P   I W  +G+P+   +R  T    G  + D+   +  DSG Y+C   N +G
Sbjct: 293  IP--AIRWLKDGRPLPADSRW-TKRITGLTISDL---RTEDSGTYICEVTNTFG 340



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-- 3870
            RG  S+    EP    P K I+   + T    + VR  C      DP   ++W ++ +  
Sbjct: 1312 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCN--SVGDPAPAVKWTKDSEDS 1369

Query: 3871 LLP-SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
             +P S   +R ++  G  +L +  V AEDSG Y C A N  G D     +  +  PD
Sbjct: 1370 AIPVSMDGHRLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPD 1424



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 6/77 (7%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            +V  G  V   C     G P   I W  +GRP    SR  T    G   L I  +   D+
Sbjct: 275  EVWAGHTVELPCTAS--GYPIPAIRWLKDGRPLPADSR-WTKRITG---LTISDLRTEDS 328

Query: 3766 GEYTCRATNKWGSATTT 3782
            G Y C  TN +GSA  T
Sbjct: 329  GTYICEVTNTFGSAEAT 345



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G T    C     G P   + W ++ + +   SR TK        +TIS +R ED G Y+
Sbjct: 279  GHTVELPCTAS--GYPIPAIRWLKDGRPLPADSRWTKR----ITGLTISDLRTEDSGTYI 332

Query: 2451 CRASNLLG 2458
            C  +N  G
Sbjct: 333  CEVTNTFG 340



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 5/120 (4%)

Query: 240 ITK-RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT 298
           ITK +Y GE+       +  +    S P I     + ++  G   +     SG P P + 
Sbjct: 238 ITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIR 297

Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           W K+G+ L   ++     T   T L + + +  DSG Y     N  G    +G L V  P
Sbjct: 298 WLKDGRPLPADSR----WTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 353



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G +    C    YP P +R  W  +G+ L +  R+ T    G    D+ T   EDSG Y 
Sbjct: 279  GHTVELPCTASGYPIPAIR--WLKDGRPLPADSRW-TKRITGLTISDLRT---EDSGTYI 332

Query: 1919 CKAINNLGQA 1928
            C+  N  G A
Sbjct: 333  CEVTNTFGSA 342



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 9/103 (8%)

Query: 53  ESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL 112
           +S+G R  +T   P E  P I +       +A G   +      G P P + W +   PL
Sbjct: 249 QSNGARLSVTD--PAESIPTILDGFHSQEVWA-GHTVELPCTASGYPIPAIRWLKDGRPL 305

Query: 113 VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
              ++++ R    TG   L I  +   D G Y C   N +G A
Sbjct: 306 PADSRWTKRI---TG---LTISDLRTEDSGTYICEVTNTFGSA 342



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 6/82 (7%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  +    S  V     V   C       P +R  W ++G+ LP+  R+          L
Sbjct: 265  PTILDGFHSQEVWAGHTVELPCTASGYPIPAIR--WLKDGRPLPADSRWTK----RITGL 318

Query: 3890 DILYVYAEDSGEYICRAVNDFG 3911
             I  +  EDSG YIC   N FG
Sbjct: 319  TISDLRTEDSGTYICEVTNTFG 340



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
            G P   + W  +G+PL   +R+T         +    +  EDSG Y+C  TN +G  E  
Sbjct: 290  GYPIPAIRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 345

Query: 4061 AVI 4063
             ++
Sbjct: 346  GIL 348



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P   I W  +G+ + A  R+ T    G    D+     EDSGTY+C+ TN  G A  T  
Sbjct: 292  PIPAIRWLKDGRPLPADSRW-TKRITGLTISDLR---TEDSGTYICEVTNTFGSAEATGI 347

Query: 2199 LKVAGHRNIIL 2209
            L V    ++ L
Sbjct: 348  LMVIDPLHVTL 358



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 41/161 (25%), Positives = 67/161 (41%), Gaps = 20/161 (12%)

Query: 4644 CKIVGKPLPTVQWY--KGDKL--IKPSKYFQMSRTADEYTLRIS--EAFPEDEGDYKCVA 4697
            C   G P   ++WY   GD +  +   ++   + T   Y    S   +F  D  DY C A
Sbjct: 86   CPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDN-DYFCTA 144

Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK---PTIQW 4754
             N+AG++  +  ++V    +    P    + D     G  A FK  I S ++     + W
Sbjct: 145  ENAAGKIR-SPNIRVKAVFRE---PYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSW 200

Query: 4755 LREG-ALIPETPDFQMIHEGNNAVLLIGNTYEEDT-GTFTC 4793
             ++  ++IPE   F   H G    L I +  +ED   T+ C
Sbjct: 201  EKDTVSIIPENRFFITYHGG----LYISDVQKEDALSTYRC 237



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 4/54 (7%)

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            + W K+G+P+    R+          L I DL  EDSG Y C   N  G+ E +
Sbjct: 296  IRWLKDGRPLPADSRWTK----RITGLTISDLRTEDSGTYICEVTNTFGSAEAT 345



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLL----HK-NRFTPIYDFGYVAMNFGWVYPEDSGEY 4046
            +F    A  G P   V W  + +P++    H+ N++T         MN       D G Y
Sbjct: 463  QFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVY 522

Query: 4047 LCRATNLYGMDETKAVIKTTGKPGI 4071
             C A NL G  E +A I   G P I
Sbjct: 523  RCTARNLVGSAEYQARINVRGPPSI 547



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 3710 GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA-LDIDYIYARDAGEY 3768
            G  ++  C V   GD  +RI W  +G+   +GS V T+    F++ L I  +  +  G Y
Sbjct: 649  GQLLYIPCVVSS-GDMPIRITWRKDGQVIISGSGV-TIESKEFMSSLQISSVSLKHNGNY 706

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
            TC A+N   + +   ++        V++     G+ G+
Sbjct: 707  TCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGK 744



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%)

Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHG 3639
            ++   D  +R+ W  +G+ +++GS V TI    F+  L+I  V  +  G YTC A+N   
Sbjct: 657  VVSSGDMPIRITWRKDGQVIISGSGV-TIESKEFMSSLQISSVSLKHNGNYTCIASN--A 713

Query: 3640 EATVSCKLQV 3649
             ATVS + Q+
Sbjct: 714  AATVSRERQL 723



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PPRFV Q  +Q  +   +     C +   G P  KV W  + K   +  ++ P+   G +
Sbjct: 728  PPRFVVQPNNQDGIYG-KAGVLNCSVD--GYPPPKVMWK-HAKGSGNPQQYHPVPLTGRI 783

Query: 4032 ------AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
                  ++    V  ED G YLC+A+N  G D +K++  T   P ++
Sbjct: 784  QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI 830



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 18/122 (14%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMP-MKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
            R N  E  +      A  ++I+     T P MKD+R+  N           VGDP   V+
Sbjct: 1312 RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNS----------VGDPAPAVK 1361

Query: 1746 WLRNG----VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
            W ++     +P+        +H  G   L ++ V  EDSG YTC A N  G       L 
Sbjct: 1362 WTKDSEDSAIPVSMDGH-RLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLL 1418

Query: 1802 VQ 1803
            VQ
Sbjct: 1419 VQ 1420



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 7/75 (9%)

Query: 936  IGDSTLRVEWLKDGR----PVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            +GD    V+W KD      PV          N     L +++V   D+G+YTC A N  G
Sbjct: 1353 VGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNG---TLLLRAVKAEDSGYYTCTATNTGG 1409

Query: 992  QATTSANLTIVTKKD 1006
              T   NL +    D
Sbjct: 1410 FDTIIVNLLVQVPPD 1424


>BC031063-1|AAH31063.1|  602|Homo sapiens IGSF10 protein protein.
          Length = 602

 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 107/413 (25%), Positives = 156/413 (37%), Gaps = 52/413 (12%)

Query: 4408 SKPPIF-----TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-T 4461
            SKPP+      ++ +       H +  F+   +G P P + W   +     +P +    T
Sbjct: 211  SKPPLINGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRIT 270

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
                  L IR V + DSA F  VA N GG +     L V E  R+       P+F     
Sbjct: 271  VHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRR-------PTFRNPFN 323

Query: 4522 NVNVTS-GQLVRLDTKVTGTKPIDVYW-LKNGKKVQ--PDIRNKILEEDGTYTLLILEAY 4577
               V   G+   L+  V G  P ++ W L NG +    P     ++  +G++  +I +  
Sbjct: 324  EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSF--IISKTT 381

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
             +D+GKY C A N  G      E +V L   + KP   T A    P  ++ +       G
Sbjct: 382  REDAGKYRCAARNKVGYI----EKLVILEIGQ-KPVILTYA----PGTVKGIS------G 426

Query: 4638 QAIEFSCKIVGKPLPTVQW-----YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            +++   C   G P P ++W     Y  D+     KY       D  TL I EA   D G+
Sbjct: 427  ESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI----LHDNGTLVIKEATAYDRGN 482

Query: 4693 YKCVAYNSAGRVTVAAKLK-VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            Y C A NS G   +   +  V  P +  N P     R IV   G   Q         KP 
Sbjct: 483  YICKAQNSVGHTLITVPVMIVAYPPRITNRPP----RSIVTRTGAAFQLHCVALGVPKPE 538

Query: 4752 IQWLREGALIPETPDFQMIHEGN----NAVLLIGNTYEEDTGTFTCRATTAAG 4800
            I W      +  T   +  H          L+I N    D+G + C A    G
Sbjct: 539  ITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 591



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 55/164 (33%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 411 FDCRVTGRPYPEVTWFINDRQIRDD--YNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
           FDCR  G P PEV W + D        Y  +I V+++G   L I NV LSDS    CVAR
Sbjct: 238 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 295

Query: 469 NKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTPTPRITW-QK 526
           N+ GE+    +L V+  E +  P F   F+   V + G+   LN    G P P I W   
Sbjct: 296 NEGGESVLVVQLEVL--EMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILP 353

Query: 527 DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           +G      P+   +      +  I +    DA  Y+C A+N  G
Sbjct: 354 NGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 397



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 79/324 (24%), Positives = 135/324 (41%), Gaps = 38/324 (11%)

Query: 263 VSPPKIAQKPRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           + P KI  K    K +  G D Q   + SG+P P ++W      +IN+            
Sbjct: 14  LKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAM---------- 63

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
                  Q  DSGH T      N   +    + V        +   + Y  +T  ++ E 
Sbjct: 64  -------QADDSGHRTRRYTLFNNGTLYFNKVGVAE------EGDYTCYAQNTLGKD-EM 109

Query: 382 RIEISEKALAPQFVKVCQ-DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
           ++ ++    AP+  +  + ++ +  G     DC VTG P P++ W +    +      + 
Sbjct: 110 KVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRY 169

Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER--FS 498
             + +G+  L I  V L DSG   CVARN SG+     +L+V+ K  ++   +  R    
Sbjct: 170 TFHANGS--LTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTSRTVIK 227

Query: 499 TLNVREGEPVVLNARAVGTPTPRITW-QKDGVPIIP---NPELRIHTDGGASTLDIPRAK 554
              VR  +    + RA GTP+P + W   D + +        + +H +G   TL+I   +
Sbjct: 228 ATAVRHSKK-HFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG---TLEIRNVR 283

Query: 555 ASDAAWYQCTAQNVAGSTATRARL 578
            SD+A + C A+N  G +    +L
Sbjct: 284 LSDSADFICVARNEGGESVLVVQL 307



 Score = 75.4 bits (177), Expect = 5e-12
 Identities = 94/426 (22%), Positives = 154/426 (36%), Gaps = 46/426 (10%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP---DFQIH- 4460
            +KP+K  I  K+    +V   +  + + +  G P+P I W   +  + N+    D   H 
Sbjct: 14   LKPAK--IDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHR 71

Query: 4461 ----TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
                T      L   +V V +   +   A+N  G  +   +L V     + R        
Sbjct: 72   TRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS------ 125

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL-KNGKKVQPDIRNKILEEDGTYTLLILE 4575
                 N  + +G    LD +VTG     ++WL  +   +   I       +G+ T+  ++
Sbjct: 126  --NKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK 183

Query: 4576 AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA 4635
                DSG+Y CVA N +G+               D    +    + PP I      + V 
Sbjct: 184  LL--DSGEYVCVARNPSGD---------------DTKMYKLDVVSKPPLINGLYTSRTVI 226

Query: 4636 EGQAIE-----FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY-TLRISEAFPED 4689
            +  A+      F C+  G P P V W   D +   + Y+    T  +  TL I      D
Sbjct: 227  KATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSD 286

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE-GQPAQFKTQITSKI 4748
              D+ CVA N  G   +  +L+V +  +        P  + +V + G+       +    
Sbjct: 287  SADFICVARNEGGESVLVVQLEVLEMLRRPTFR--NPFNEKIVAQLGKSTALNCSVDGNP 344

Query: 4749 KPTIQW-LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             P I W L  G      P        +N   +I  T  ED G + C A    G +E    
Sbjct: 345  PPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVI 404

Query: 4808 LVVKSK 4813
            L +  K
Sbjct: 405  LEIGQK 410



 Score = 73.7 bits (173), Expect = 1e-11
 Identities = 95/401 (23%), Positives = 153/401 (38%), Gaps = 40/401 (9%)

Query: 4421 RVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSILIIRQVFVEDS 4478
            R+   + A  + E  G+P P I W     P  +   F I  +TF     L I +V + DS
Sbjct: 131  RIKAGDTAVLDCEVTGDPKPKIFWL---LPSNDMISFSIDRYTFHANGSLTINKVKLLDS 187

Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
              +  VA N  G       L V  K      G+      + A  V  +       D +  
Sbjct: 188  GEYVCVARNPSGDDTKMYKLDVVSKPPL-INGLYTSRTVIKATAVRHSKKHF---DCRAE 243

Query: 4539 GTKPIDVYWLK--NGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            GT   +V W+   N     P   ++I + ++GT  L I      DS  + CVA N  GE 
Sbjct: 244  GTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVARNEGGE- 300

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFSCKIVGKPLPTV 4654
               +  VV L   +   +P  +          P  +KIVA+ G++   +C + G P P +
Sbjct: 301  ---SVLVVQLEVLEMLRRPTFR---------NPFNEKIVAQLGKSTALNCSVDGNPPPEI 348

Query: 4655 QWY--KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             W    G +     + +Q    A   +  IS+   ED G Y+C A N  G +    KL +
Sbjct: 349  IWILPNGTRFSNGPQSYQY-LIASNGSFIISKTTREDAGKYRCAARNKVGYI---EKLVI 404

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ---M 4769
             +  Q   +    P   +    G+            KP I+W      + + P      +
Sbjct: 405  LEIGQKPVILTYAP-GTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI 463

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +H+  N  L+I      D G + C+A  + G    +  +++
Sbjct: 464  LHD--NGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMI 502



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 58/200 (29%), Positives = 90/200 (45%), Gaps = 20/200 (10%)

Query: 382 RIEISEKALAPQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWFI--NDRQIRDDYNH 438
           ++E+ E    P F     ++ V + GK T  +C V G P PE+ W +    R      ++
Sbjct: 306 QLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSY 365

Query: 439 KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVER 496
           + L+  + N + +I+  T  D+G   C ARNK G       L + +K  ++  AP  V+ 
Sbjct: 366 QYLI--ASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKG 423

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR----IHTDGGASTLDIPR 552
            S      GE + L+  + G P P I W      ++  P++     +H +G   TL I  
Sbjct: 424 IS------GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNG---TLVIKE 474

Query: 553 AKASDAAWYQCTAQNVAGST 572
           A A D   Y C AQN  G T
Sbjct: 475 ATAYDRGNYICKAQNSVGHT 494



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 74/286 (25%), Positives = 112/286 (39%), Gaps = 33/286 (11%)

Query: 4435 DGEPLPLIKWYRENFP-IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            DG P P I W   N     N P    +  ++    II +   ED+  +   A N+ G  +
Sbjct: 341  DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIE 400

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGK 4552
                L + +K         P   T     V   SG+ + L     G    ++ W + +G 
Sbjct: 401  KLVILEIGQK---------PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGY 451

Query: 4553 KV-QPDIRNK-ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
             V +P I  K IL ++GT  L+I EA   D G Y C A NS G        ++++P    
Sbjct: 452  VVDRPQINGKYILHDNGT--LVIKEATAYDRGNYICKAQNSVGHT------LITVPVMIV 503

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
               P  +  N PP  I      +   G A +  C  +G P P + W   D  +  +   +
Sbjct: 504  AYPP--RITNRPPRSI------VTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKE 555

Query: 4671 MSRTADEY----TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +  +++     TL I      D G YKC A N  G    A  ++V
Sbjct: 556  RTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 601



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 46/174 (26%), Positives = 73/174 (41%), Gaps = 15/174 (8%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVTLSDSGVV 463
           G+     C   G P P + W +    +  R   N K +++++G   L+I   T  D G  
Sbjct: 426 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 483

Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRI 522
            C A+N  G T     + ++       P+   R   ++  R G    L+  A+G P P I
Sbjct: 484 ICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEI 539

Query: 523 TWQKDGVPIIPNPELRIHTDGGAS-----TLDIPRAKASDAAWYQCTAQNVAGS 571
           TW+     ++     +  T G        TL I   + SD+  Y+CTA+N  GS
Sbjct: 540 TWEMPDHSLLSTAS-KERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 592



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 66/291 (22%), Positives = 105/291 (36%), Gaps = 23/291 (7%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE--CNKYSMRYNEQTG 127
           +P I +    N R   G  A  + ++ G+P P + W      ++    ++Y+   N    
Sbjct: 119 APRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANG--- 175

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAI----CSVYIQPE--GXXXXXXXXXXXXXYRH 181
             SL I ++   D GEY C ARN  G+        V  +P                  RH
Sbjct: 176 --SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTSRTVIKATAVRH 233

Query: 182 VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE--S 239
             +  + +A GT             +  T     S     K  T E R +R     +   
Sbjct: 234 SKKHFDCRAEGTPS-PEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFIC 292

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRV 297
           + +   GES + +  E+   L  +  P   + P N K+  Q G        + GNP P +
Sbjct: 293 VARNEGGESVLVVQLEV---LEMLRRPTF-RNPFNEKIVAQLGKSTALNCSVDGNPPPEI 348

Query: 298 TW-FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
            W   NG R  N  +       ++ +  +  T + D+G Y   A N  G I
Sbjct: 349 IWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYI 399



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 42/142 (29%), Positives = 58/142 (40%), Gaps = 7/142 (4%)

Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF 3151
            ++ HR R    F    L        + G Y+C A N  G+ E+ V L  +  +    PR 
Sbjct: 67   DSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAA----PRI 122

Query: 3152 TTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDI 3211
                +  + +K G +A  +C V    DP  KI W      M  S  I   +      L I
Sbjct: 123  RQSNKTNKRIKAGDTAVLDCEV--TGDPKPKIFWLLPSNDM-ISFSIDRYTFHANGSLTI 179

Query: 3212 AYTQNHDSGEYVCRAYNKYGED 3233
               +  DSGEYVC A N  G+D
Sbjct: 180  NKVKLLDSGEYVCVARNPSGDD 201



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 265 PPKIAQKP-RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS----NKHEIITTHN 319
           PP+I  +P R+   + GA  Q      G P+P +TW      L+++      H     H 
Sbjct: 506 PPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHL 565

Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
             TL ++N Q SDSG Y   A+NP G    + Y+ V
Sbjct: 566 QGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 601



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 19/58 (32%), Positives = 32/58 (55%)

Query: 4122 VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGK 4179
            ++ G+ A   C VTG PKP++ WLL  N +++ S  + T+       I K +  D+G+
Sbjct: 132  IKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGE 189



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 16/125 (12%)

Query: 3113 TKTT--DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ-NIEGLKDGQSAHF 3169
            +KTT  D+G Y C A NK G  E  V LE      GQKP   T+    ++G+  G+S   
Sbjct: 378  SKTTREDAGKYRCAARNKVGYIEKLVILEI-----GQKPVILTYAPGTVKGI-SGESLSL 431

Query: 3170 ECTVVPVDDPDMK---IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             C    +  P++K      Y   +P  +   I  + D G +V+  A    +D G Y+C+A
Sbjct: 432  HCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI--LHDNGTLVIKEATA--YDRGNYICKA 487

Query: 3227 YNKYG 3231
             N  G
Sbjct: 488  QNSVG 492



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 11/128 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   + +DS  + C A N+ G++ + V+LE ++  +  +P F          + G+S 
Sbjct: 277  LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR--RPTFRNPFNEKIVAQLGKST 334

Query: 3168 HFECTVVPVDDPDMKIEW-YHNGQPMRH---STRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
               C+V    +P  +I W   NG    +   S +    S+  F+   I+ T   D+G+Y 
Sbjct: 335  ALNCSV--DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFI---ISKTTREDAGKYR 389

Query: 3224 CRAYNKYG 3231
            C A NK G
Sbjct: 390  CAARNKVG 397



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            T  P  +   K    IK G  A  +   E  GD   ++ WL     + + S I  +    
Sbjct: 117  TAAPRIRQSNKTNKRIKAGDTAVLDC--EVTGDPKPKIFWLLPSNDMISFS-IDRYTFHA 173

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
              +LTI  V + D+G Y C A N  G  T    L +V+K  +I
Sbjct: 174  NGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLI 216



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 3/81 (3%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH---ALMITNVTLSDSGV 462
           G   +  C   G P PE+TW + D  +    + +        H    L+I N   SDSG+
Sbjct: 522 GAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGI 581

Query: 463 VTCVARNKSGETAFQCRLNVI 483
             C A+N  G       + VI
Sbjct: 582 YKCTAKNPLGSDYAATYIQVI 602



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 7/100 (7%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLV----ECNKYSMRYN 123
           +P+    +Q F+  +   G + + + K  G+P P +SW+     ++    + +    R  
Sbjct: 15  KPAKIDHKQYFRK-QVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTR 73

Query: 124 EQT--GDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             T   + +L   ++G  +EG+YTC A+N  G+    V++
Sbjct: 74  RYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHL 113



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSR-YKLTYDGMYHFDIPKTRQY 4175
            + +  + G+     C V G+P P ++W+L NG    NG + Y+        F I KT + 
Sbjct: 324  EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTRE 383

Query: 4176 DTGK 4179
            D GK
Sbjct: 384  DAGK 387



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVL---QSGH 1891
            V + + Q P  +T   G  K   G+S    C  +  P PN  ++W   +G V+   Q   
Sbjct: 403  VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPN--IKWTMPSGYVVDRPQING 460

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
            +Y   +D G   +   T Y  D G Y CKA N++G  + ++
Sbjct: 461  KY-ILHDNGTLVIKEATAY--DRGNYICKAQNSVGHTLITV 498



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 9/107 (8%)

Query: 1840 VNQAPRFITQLNGPTK-LSEGQSAHYECRIEPYPDPNMRVEWYF--NGKVLQSGHRYRTS 1896
            +  APR I Q N   K +  G +A  +C +    DP  ++ W    N  +  S  RY T 
Sbjct: 116  ITAAPR-IRQSNKTNKRIKAGDTAVLDCEVTG--DPKPKIFWLLPSNDMISFSIDRY-TF 171

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            +  G  +L I  V   DSGEY C A N  G      +L+V SK  +I
Sbjct: 172  HANG--SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLI 216



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 5/101 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTLNDFGFI 3753
            PR     K N  +  G     DC V   GDP  +I W        + S   +T +  G  
Sbjct: 120  PRIRQSNKTNKRIKAGDTAVLDCEV--TGDPKPKIFWLLPSNDMISFSIDRYTFHANG-- 175

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            +L I+ +   D+GEY C A N  G  T   K+   +K  ++
Sbjct: 176  SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLI 216



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 7/86 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWF--RNEKLIEDSSRITKTHDFGY 2433
            P   Q  +    I+ G TA  DC +   GDP  K+ W    N+ +     R T  H  G 
Sbjct: 120  PRIRQSNKTNKRIKAGDTAVLDCEV--TGDPKPKIFWLLPSNDMISFSIDRYT-FHANG- 175

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             S+TI+ V+  D G Y+C A N  G+
Sbjct: 176  -SLTINKVKLLDSGEYVCVARNPSGD 200



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 6/137 (4%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHL--TIDWFHNGQKIRAGHRYRTTHD 2163
            GQ+PV LT          G+     C  + I  P++  T+   +   + +   +Y   HD
Sbjct: 408  GQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY-ILHD 466

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL 2223
             G + +     Y  D G Y+CKA N +G  + T  + +  +   I + + P  +      
Sbjct: 467  NGTLVIKEATAY--DRGNYICKAQNSVGHTLITVPVMIVAYPPRITN-RPPRSIVTRTGA 523

Query: 2224 EAQGHSTRIEVEEPKIS 2240
              Q H   + V +P+I+
Sbjct: 524  AFQLHCVALGVPKPEIT 540



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 45/161 (27%), Positives = 61/161 (37%), Gaps = 8/161 (4%)

Query: 3075 TGDQSMVIEWFY-NGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            TGD    I W   +   I  S    T +A G   L I   K  DSG Y C A N  G   
Sbjct: 145  TGDPKPKIFWLLPSNDMISFSIDRYTFHANGS--LTINKVKLLDSGEYVCVARNPSGDDT 202

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHN--GQP 3191
               KL+ V K       +T+              HF+C       P++      N     
Sbjct: 203  KMYKLDVVSKPPLINGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTA 262

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              + +RI TV   G   L+I   +  DS +++C A N+ GE
Sbjct: 263  PYYGSRI-TVHKNG--TLEIRNVRLSDSADFICVARNEGGE 300



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 956  SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011
            +R  T FN G   L    V V + G YTC A N +G+     +LT++T    I +S
Sbjct: 72   TRRYTLFNNG--TLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS 125



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/125 (26%), Positives = 45/125 (36%), Gaps = 6/125 (4%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G Y C+A N  G   I+V +  V       PR T         + G +    C  + V
Sbjct: 479  DRGNYICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGV 534

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV--VLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P++  E   +      S      S+   +   L I   Q  DSG Y C A N  G D+
Sbjct: 535  PKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDY 594

Query: 3235 TRATI 3239
                I
Sbjct: 595  AATYI 599



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 12/96 (12%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVR-----FECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
            +VS PP       S TV ++  VR     F+CR E    P+  + W     +  +   Y 
Sbjct: 209  VVSKPPLINGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPE--VMWIMPDNIFLTAPYYG 266

Query: 3880 ---TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
               TV+  G  +L+I  V   DS ++IC A N+ GE
Sbjct: 267  SRITVHKNG--TLEIRNVRLSDSADFICVARNEGGE 300


>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
            protein.
          Length = 2623

 Score = 88.6 bits (210), Expect = 5e-16
 Identities = 101/404 (25%), Positives = 151/404 (37%), Gaps = 39/404 (9%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI---KNSPDFQIHTFSTK 4465
            KP I   K     +  +  A    E  G PLP I W R    +   K   + ++      
Sbjct: 1647 KPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVL-PN 1705

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
              L I++V ++D   +   A N  GT      L V            P       + + V
Sbjct: 1706 GTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVV--------SYPPRILERRTKEITV 1757

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD----IRNKILEEDGTYTLLILEAYPQDS 4581
             SG  V L  +  G     V W+   + V  +     R  ++  DGT  L  L  Y  D 
Sbjct: 1758 HSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIY--DR 1815

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAI 4640
            G Y+CVA N  G+               D    + +   APP I+E  +  IV   G+++
Sbjct: 1816 GFYKCVASNPGGQ---------------DSLLVKIQVIAAPPVILEQRRQVIVGTWGESL 1860

Query: 4641 EFSCKIVGKPLPTVQWYKGDKL-IKPSKYFQMSR-TADEYTLRISEAFPEDEGDYKCVAY 4698
            +  C   G P P+V W   D   +KP ++           TL I      D G Y+C+A 
Sbjct: 1861 KLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIAT 1920

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW-LRE 4757
            +S G       L + +   +  + A +  R  V + G         T + KP I W L  
Sbjct: 1921 SSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNF-GDKLLLNCSATGEPKPQIMWRLPS 1979

Query: 4758 GALIPETPDF-QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             A++ +       IH   N  L IG+  E+D+G + C A    G
Sbjct: 1980 KAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVARNKMG 2023



 Score = 88.2 bits (209), Expect = 6e-16
 Identities = 107/413 (25%), Positives = 155/413 (37%), Gaps = 52/413 (12%)

Query: 4408 SKPPIFT-----KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-T 4461
            SKPP+       + +       H +  F+   +G P P + W   +     +P +    T
Sbjct: 2232 SKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRIT 2291

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
                  L IR V + DSA F  VA N GG +     L V E  R+       P+F     
Sbjct: 2292 VHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRR-------PTFRNPFN 2344

Query: 4522 NVNVTS-GQLVRLDTKVTGTKPIDVYW-LKNGKKVQ--PDIRNKILEEDGTYTLLILEAY 4577
               V   G+   L+  V G  P ++ W L NG +    P     ++  +G++  +I +  
Sbjct: 2345 EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSF--IISKTT 2402

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
             +D+GKY C A N  G      E +V L   + KP   T A    P  ++ +       G
Sbjct: 2403 REDAGKYRCAARNKVGYI----EKLVILEIGQ-KPVILTYA----PGTVKGIS------G 2447

Query: 4638 QAIEFSCKIVGKPLPTVQW-----YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            +++   C   G P P ++W     Y  D+     KY       D  TL I EA   D G+
Sbjct: 2448 ESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI----LHDNGTLVIKEATAYDRGN 2503

Query: 4693 YKCVAYNSAGRVTVAAKLK-VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            Y C A NS G   +   +  V  P +  N P     R IV   G   Q         KP 
Sbjct: 2504 YICKAQNSVGHTLITVPVMIVAYPPRITNRPP----RSIVTRTGAAFQLHCVALGVPKPE 2559

Query: 4752 IQWLREGALIPETPDFQMIHEGN----NAVLLIGNTYEEDTGTFTCRATTAAG 4800
            I W      +  T   +  H          L+I N    D+G + C A    G
Sbjct: 2560 ITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 2612



 Score = 85.0 bits (201), Expect = 6e-15
 Identities = 110/500 (22%), Positives = 187/500 (37%), Gaps = 57/500 (11%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            GNP P + WTR  + L    +      +   + +L I+++   D G+Y C+A N +G   
Sbjct: 1674 GNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASNLFGTDH 1733

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHK--AYGTQGYTTEQSRQTQKVAYTNGTD 214
              V +                   H   TVE K  A G    T       Q V  +  + 
Sbjct: 1734 LHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVV-SESSQ 1792

Query: 215  HSSTDDFKVD---TFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQK 271
             S      VD         + +  F + +     G+  + +  ++       +PP I ++
Sbjct: 1793 GSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVI-----AAPPVILEQ 1847

Query: 272  PRNSKLQE-GADAQFQVQLSGNPRPRVTWFKNGQRLINSNK--HEIITTHNHTTLRVRNT 328
             R   +   G   +      G P+P V W  +    +   +  +  +   ++ TL +RN 
Sbjct: 1848 RRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNL 1907

Query: 329  QKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEK 388
              SD G Y         CI TS               +R   +   ++R T  RIE + +
Sbjct: 1908 ASSDRGTYE--------CIATSS-----------TGSERRVVMLTMEERVTSPRIEAASQ 1948

Query: 389  ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI--LVNESG 446
                      +  +V  G     +C  TG P P++ W +  + + D   H++   ++   
Sbjct: 1949 ----------KRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQ-QHRVGSWIHVYP 1997

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            N +L I +VT  DSGV  CVARNK G+      +++  K   +  K   ++    V  G+
Sbjct: 1998 NGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHK---QYFRKQVLHGK 2054

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNP--------ELRIHTDGGASTLDIPRAKASDA 558
               ++ +A G+P P I+W      +I N           R +T     TL   +   ++ 
Sbjct: 2055 DFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEE 2114

Query: 559  AWYQCTAQNVAGSTATRARL 578
              Y C AQN  G    +  L
Sbjct: 2115 GDYTCYAQNTLGKDEMKVHL 2134



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 55/164 (33%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 411  FDCRVTGRPYPEVTWFINDRQIRDD--YNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
            FDCR  G P PEV W + D        Y  +I V+++G   L I NV LSDS    CVAR
Sbjct: 2259 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 2316

Query: 469  NKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTPTPRITW-QK 526
            N+ GE+    +L V+  E +  P F   F+   V + G+   LN    G P P I W   
Sbjct: 2317 NEGGESVLVVQLEVL--EMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILP 2374

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +G      P+   +      +  I +    DA  Y+C A+N  G
Sbjct: 2375 NGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 2418



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 79/324 (24%), Positives = 135/324 (41%), Gaps = 38/324 (11%)

Query: 263  VSPPKIAQKPRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
            + P KI  K    K +  G D Q   + SG+P P ++W      +IN+            
Sbjct: 2035 LKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAM---------- 2084

Query: 322  TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
                   Q  DSGH T      N   +    + V        +   + Y  +T  ++ E 
Sbjct: 2085 -------QADDSGHRTRRYTLFNNGTLYFNKVGVAE------EGDYTCYAQNTLGKD-EM 2130

Query: 382  RIEISEKALAPQFVKVCQ-DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            ++ ++    AP+  +  + ++ +  G     DC VTG P P++ W +    +      + 
Sbjct: 2131 KVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRY 2190

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER--FS 498
              + +G+  L I  V L DSG   CVARN SG+     +L+V+ K  ++   +  R    
Sbjct: 2191 TFHANGS--LTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIK 2248

Query: 499  TLNVREGEPVVLNARAVGTPTPRITW-QKDGVPIIP---NPELRIHTDGGASTLDIPRAK 554
               VR  +    + RA GTP+P + W   D + +        + +H +G   TL+I   +
Sbjct: 2249 ATAVRHSKK-HFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG---TLEIRNVR 2304

Query: 555  ASDAAWYQCTAQNVAGSTATRARL 578
             SD+A + C A+N  G +    +L
Sbjct: 2305 LSDSADFICVARNEGGESVLVVQL 2328



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 94/426 (22%), Positives = 155/426 (36%), Gaps = 46/426 (10%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP---DFQIH- 4460
            +KP+K  I  K+    +V   +  + + +  G P+P I W   +  + N+    D   H 
Sbjct: 2035 LKPAK--IDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHR 2092

Query: 4461 ----TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
                T      L   +V V +   +   A+N  G  +   +L V     + R        
Sbjct: 2093 TRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS------ 2146

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL-KNGKKVQPDIRNKILEEDGTYTLLILE 4575
                 N  + +G    LD +VTG     ++WL  +   +   I       +G+ T+  ++
Sbjct: 2147 --NKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK 2204

Query: 4576 AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA 4635
                DSG+Y CVA N +G+               D    +    + PP I     ++ V 
Sbjct: 2205 LL--DSGEYVCVARNPSGD---------------DTKMYKLDVVSKPPLINGLYTNRTVI 2247

Query: 4636 EGQAIE-----FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY-TLRISEAFPED 4689
            +  A+      F C+  G P P V W   D +   + Y+    T  +  TL I      D
Sbjct: 2248 KATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSD 2307

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE-GQPAQFKTQITSKI 4748
              D+ CVA N  G   +  +L+V +  +        P  + +V + G+       +    
Sbjct: 2308 SADFICVARNEGGESVLVVQLEVLEMLRRPTFR--NPFNEKIVAQLGKSTALNCSVDGNP 2365

Query: 4749 KPTIQW-LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             P I W L  G      P        +N   +I  T  ED G + C A    G +E    
Sbjct: 2366 PPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVI 2425

Query: 4808 LVVKSK 4813
            L +  K
Sbjct: 2426 LEIGQK 2431



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 97/419 (23%), Positives = 150/419 (35%), Gaps = 45/419 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI--KNSPDFQIHTFSTKSI 4467
            P I  ++ +   V        +   +G P P + W   N  +  ++S   +    +    
Sbjct: 1745 PRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGT 1804

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV-T 4526
            L++  + + D   +  VA N GG       + V            PP      + V V T
Sbjct: 1805 LVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIA---------APPVILEQRRQVIVGT 1855

Query: 4527 SGQLVRLDTKVTGTKPIDVYW-LKNGKKVQP-DIRNKILEEDGTYTLLILEAYPQDSGKY 4584
             G+ ++L     GT    VYW L +G +V+P    N  L      TL I      D G Y
Sbjct: 1856 WGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTY 1915

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
            EC+A +S G  R     VV L   +    P+ +AA+         K   V  G  +  +C
Sbjct: 1916 ECIATSSTGSER----RVVMLTMEERVTSPRIEAASQ--------KRTEVNFGDKLLLNC 1963

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMS--RTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
               G+P P + W    K +   ++   S        +L I     +D G Y CVA N  G
Sbjct: 1964 SATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVARNKMG 2023

Query: 4703 RVTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW-LREGAL 4760
               +   + +  +P + D+           V  G+  Q   + +    P I W L +G +
Sbjct: 2024 DDLILMHVSLRLKPAKIDHKQYFRK----QVLHGKDFQVDCKASGSPVPEISWSLPDGTM 2079

Query: 4761 IPETPDFQMIHEG---------NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            I      Q    G         NN  L        + G +TC A    G+ E    L V
Sbjct: 2080 INNA--MQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTV 2136



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 98/406 (24%), Positives = 153/406 (37%), Gaps = 50/406 (12%)

Query: 4421 RVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSILIIRQVFVEDS 4478
            R+   + A  + E  G+P P I W     P  +   F I  +TF     L I +V + DS
Sbjct: 2152 RIKAGDTAVLDCEVTGDPKPKIFWL---LPSNDMISFSIDRYTFHANGSLTINKVKLLDS 2208

Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR-----L 4533
              +  VA N  G       L V  K         PP       N  V     VR      
Sbjct: 2209 GEYVCVARNPSGDDTKMYKLDVVSK---------PPLINGLYTNRTVIKATAVRHSKKHF 2259

Query: 4534 DTKVTGTKPIDVYWLK--NGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            D +  GT   +V W+   N     P   ++I + ++GT  L I      DS  + CVA N
Sbjct: 2260 DCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVARN 2317

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFSCKIVGK 4649
              GE    +  VV L   +   +P  +          P  +KIVA+ G++   +C + G 
Sbjct: 2318 EGGE----SVLVVQLEVLEMLRRPTFR---------NPFNEKIVAQLGKSTALNCSVDGN 2364

Query: 4650 PLPTVQWY--KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            P P + W    G +     + +Q    A   +  IS+   ED G Y+C A N  G +   
Sbjct: 2365 PPPEIIWILPNGTRFSNGPQSYQY-LIASNGSFIISKTTREDAGKYRCAARNKVGYI--- 2420

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
             KL + +  Q   +    P   +    G+            KP I+W      + + P  
Sbjct: 2421 EKLVILEIGQKPVILTYAP-GTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQI 2479

Query: 4768 Q---MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                ++H+  N  L+I      D G + C+A  + G    +  +++
Sbjct: 2480 NGKYILHD--NGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMI 2523



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 58/200 (29%), Positives = 90/200 (45%), Gaps = 20/200 (10%)

Query: 382  RIEISEKALAPQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWFI--NDRQIRDDYNH 438
            ++E+ E    P F     ++ V + GK T  +C V G P PE+ W +    R      ++
Sbjct: 2327 QLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSY 2386

Query: 439  KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVER 496
            + L+  + N + +I+  T  D+G   C ARNK G       L + +K  ++  AP  V+ 
Sbjct: 2387 QYLI--ASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKG 2444

Query: 497  FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR----IHTDGGASTLDIPR 552
             S      GE + L+  + G P P I W      ++  P++     +H +G   TL I  
Sbjct: 2445 IS------GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNG---TLVIKE 2495

Query: 553  AKASDAAWYQCTAQNVAGST 572
            A A D   Y C AQN  G T
Sbjct: 2496 ATAYDRGNYICKAQNSVGHT 2515



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 74/286 (25%), Positives = 112/286 (39%), Gaps = 33/286 (11%)

Query: 4435 DGEPLPLIKWYRENFP-IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            DG P P I W   N     N P    +  ++    II +   ED+  +   A N+ G  +
Sbjct: 2362 DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIE 2421

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGK 4552
                L + +K         P   T     V   SG+ + L     G    ++ W + +G 
Sbjct: 2422 KLVILEIGQK---------PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGY 2472

Query: 4553 KV-QPDIRNK-ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
             V +P I  K IL ++GT  L+I EA   D G Y C A NS G        ++++P    
Sbjct: 2473 VVDRPQINGKYILHDNGT--LVIKEATAYDRGNYICKAQNSVGHT------LITVPVMIV 2524

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
               P  +  N PP  I      +   G A +  C  +G P P + W   D  +  +   +
Sbjct: 2525 AYPP--RITNRPPRSI------VTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKE 2576

Query: 4671 MSRTADEY----TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +  +++     TL I      D G YKC A N  G    A  ++V
Sbjct: 2577 RTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 2622



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 65/248 (26%), Positives = 104/248 (41%), Gaps = 18/248 (7%)

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP-LKDK 4632
            ++  P  +   + V I   G+  C A    +L  T D         + PP I+E   K+ 
Sbjct: 1700 VQVLPNGTLSIQRVEIQDRGQYLCSAS---NLFGT-DHLHVTLSVVSYPPRILERRTKEI 1755

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA---DEYTLRISEAFPED 4689
             V  G  +E  C+  G+P PTV W   ++ +  S+  Q SR A    + TL +      D
Sbjct: 1756 TVHSGSTVELKCRAEGRPSPTVTWILANQTV-VSESSQGSRQAVVTVDGTLVLHNLSIYD 1814

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK-- 4747
             G YKCVA N  G+ ++  K++V         P +   R  V+        K   T+K  
Sbjct: 1815 RGFYKCVASNPGGQDSLLVKIQVIAAP-----PVILEQRRQVIVGTWGESLKLPCTAKGT 1869

Query: 4748 IKPTIQW-LREGALI-PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             +P++ W L +G  + P       +   +N  L I N    D GT+ C AT++ G     
Sbjct: 1870 PQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRV 1929

Query: 4806 AKLVVKSK 4813
              L ++ +
Sbjct: 1930 VMLTMEER 1937



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 46/174 (26%), Positives = 73/174 (41%), Gaps = 15/174 (8%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVTLSDSGVV 463
            G+     C   G P P + W +    +  R   N K +++++G   L+I   T  D G  
Sbjct: 2447 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 2504

Query: 464  TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRI 522
             C A+N  G T     + ++       P+   R   ++  R G    L+  A+G P P I
Sbjct: 2505 ICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEI 2560

Query: 523  TWQKDGVPIIPNPELRIHTDGGAS-----TLDIPRAKASDAAWYQCTAQNVAGS 571
            TW+     ++     +  T G        TL I   + SD+  Y+CTA+N  GS
Sbjct: 2561 TWEMPDHSLLSTAS-KERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 2613



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 47/172 (27%), Positives = 72/172 (41%), Gaps = 9/172 (5%)

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSR--TADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            C+ VG PLPT+ W +    +  SK  Q SR       TL I     +D G Y C A N  
Sbjct: 1670 CEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASNLF 1729

Query: 4702 GRVTVAAKLK-VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW-LREGA 4759
            G   +   L  V+ P +   L   T  ++I V+ G   + K +   +  PT+ W L    
Sbjct: 1730 GTDHLHVTLSVVSYPPRI--LERRT--KEITVHSGSTVELKCRAEGRPSPTVTWILANQT 1785

Query: 4760 LIPETPD-FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            ++ E+    +      +  L++ N    D G + C A+   GQ     K+ V
Sbjct: 1786 VVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQV 1837



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 44/177 (24%), Positives = 77/177 (43%), Gaps = 14/177 (7%)

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFIND-RQIRDDY---NHKILVNESGNHALMITNV 455
           +  V  G     +C   G P P V W + D  ++R  Y   + +IL+++SG   L + + 
Sbjct: 484 EHTVLVGGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMAD- 542

Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
              D+GV  C++ N         R+ V+E    +   + E      V  GE + L   + 
Sbjct: 543 -SFDTGVYHCISSNYDDADILTYRITVVEP---LVEAYQENGIHHTVFIGETLDLPCHST 598

Query: 516 GTPTPRITWQKDGVPII--PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           G P   I+W   G  ++   + + ++  +G   TL I +    D  +Y+C A N +G
Sbjct: 599 GIPDASISWVIPGNNVLYQSSRDKKVLNNG---TLRILQVTPKDQGYYRCVAANPSG 652



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 45/189 (23%), Positives = 71/189 (37%), Gaps = 18/189 (9%)

Query: 413  CRVTGRPYPEVTWFINDRQI---RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            C   G P P + W      +   +   N ++ V  +G   L I  V + D G   C A N
Sbjct: 1670 CEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGT--LSIQRVEIQDRGQYLCSASN 1727

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVE-RFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
              G       L+V+       P+ +E R   + V  G  V L  RA G P+P +TW    
Sbjct: 1728 LFGTDHLHVTLSVVS----YPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILAN 1783

Query: 529  VPIIP-----NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXX 583
              ++      + +  +  DG   TL +      D  +Y+C A N  G  +   ++     
Sbjct: 1784 QTVVSESSQGSRQAVVTVDG---TLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAA 1840

Query: 584  XXXXXXQKR 592
                  Q+R
Sbjct: 1841 PPVILEQRR 1849



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 66/291 (22%), Positives = 105/291 (36%), Gaps = 23/291 (7%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE--CNKYSMRYNEQTG 127
            +P I +    N R   G  A  + ++ G+P P + W      ++    ++Y+   N    
Sbjct: 2140 APRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANG--- 2196

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAI----CSVYIQPE--GXXXXXXXXXXXXXYRH 181
              SL I ++   D GEY C ARN  G+        V  +P                  RH
Sbjct: 2197 --SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRH 2254

Query: 182  VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE--S 239
              +  + +A GT             +  T     S     K  T E R +R     +   
Sbjct: 2255 SKKHFDCRAEGTPS-PEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFIC 2313

Query: 240  ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRV 297
            + +   GES + +  E+   L  +  P   + P N K+  Q G        + GNP P +
Sbjct: 2314 VARNEGGESVLVVQLEV---LEMLRRPTF-RNPFNEKIVAQLGKSTALNCSVDGNPPPEI 2369

Query: 298  TW-FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
             W   NG R  N  +       ++ +  +  T + D+G Y   A N  G I
Sbjct: 2370 IWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYI 2420



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 42/142 (29%), Positives = 58/142 (40%), Gaps = 7/142 (4%)

Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF 3151
            ++ HR R    F    L        + G Y+C A N  G+ E+ V L  +  +    PR 
Sbjct: 2088 DSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAA----PRI 2143

Query: 3152 TTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDI 3211
                +  + +K G +A  +C V    DP  KI W      M  S  I   +      L I
Sbjct: 2144 RQSNKTNKRIKAGDTAVLDCEV--TGDPKPKIFWLLPSNDM-ISFSIDRYTFHANGSLTI 2200

Query: 3212 AYTQNHDSGEYVCRAYNKYGED 3233
               +  DSGEYVC A N  G+D
Sbjct: 2201 NKVKLLDSGEYVCVARNPSGDD 2222



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 265  PPKIAQKP-RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS----NKHEIITTHN 319
            PP+I  +P R+   + GA  Q      G P+P +TW      L+++      H     H 
Sbjct: 2527 PPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHL 2586

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
              TL ++N Q SDSG Y   A+NP G    + Y+ V
Sbjct: 2587 QGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 2622



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 23/91 (25%), Positives = 40/91 (43%)

Query: 4122 VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGKIE 4181
            ++ G+ A   C VTG PKP++ WLL  N +++ S  + T+       I K +  D+G+  
Sbjct: 2153 IKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYV 2212

Query: 4182 VIXXXXXXXXXXXXXLKVIPRHDDYRGVLKN 4212
             +             L V+ +     G+  N
Sbjct: 2213 CVARNPSGDDTKMYKLDVVSKPPLINGLYTN 2243



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 16/125 (12%)

Query: 3113 TKTT--DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ-NIEGLKDGQSAHF 3169
            +KTT  D+G Y C A NK G  E  V LE      GQKP   T+    ++G+  G+S   
Sbjct: 2399 SKTTREDAGKYRCAARNKVGYIEKLVILEI-----GQKPVILTYAPGTVKGI-SGESLSL 2452

Query: 3170 ECTVVPVDDPDMK---IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             C    +  P++K      Y   +P  +   I  + D G +V+  A    +D G Y+C+A
Sbjct: 2453 HCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI--LHDNGTLVIKEATA--YDRGNYICKA 2508

Query: 3227 YNKYG 3231
             N  G
Sbjct: 2509 QNSVG 2513



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/92 (27%), Positives = 38/92 (41%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P I E+  K      G   + + +  G P+P V+W      +V  +    R    T D +
Sbjct: 1745 PRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGT 1804

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            L++  +   D G Y C A N  G+    V IQ
Sbjct: 1805 LVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQ 1836



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 11/128 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   + +DS  + C A N+ G++ + V+LE ++  +  +P F          + G+S 
Sbjct: 2298 LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR--RPTFRNPFNEKIVAQLGKST 2355

Query: 3168 HFECTVVPVDDPDMKIEW-YHNGQPMRH---STRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
               C+V    +P  +I W   NG    +   S +    S+  F+   I+ T   D+G+Y 
Sbjct: 2356 ALNCSV--DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFI---ISKTTREDAGKYR 2410

Query: 3224 CRAYNKYG 3231
            C A NK G
Sbjct: 2411 CAARNKVG 2418



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 37/122 (30%), Positives = 49/122 (40%), Gaps = 10/122 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT----GSRVHTLND 3749
            PPR        I V  G  V   CR E  G P+  + W    +   +    GSR   +  
Sbjct: 1744 PPRILERRTKEITVHSGSTVELKCRAE--GRPSPTVTWILANQTVVSESSQGSRQAVVTV 1801

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLES--QLPQGMSGEK 3807
             G + L    IY  D G Y C A+N  G  +   KI   A   ++LE   Q+  G  GE 
Sbjct: 1802 DGTLVLHNLSIY--DRGFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGES 1859

Query: 3808 IK 3809
            +K
Sbjct: 1860 LK 1861



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 7/88 (7%)

Query: 4637 GQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            G+ ++  C   G P  ++ W   G+ ++  S   +  +  +  TLRI +  P+D+G Y+C
Sbjct: 588  GETLDLPCHSTGIPDASISWVIPGNNVLYQSS--RDKKVLNNGTLRILQVTPKDQGYYRC 645

Query: 4696 VAYNSAG----RVTVAAKLKVTQPDQAD 4719
            VA N +G       V+ K+K  +P + D
Sbjct: 646  VAANPSGVDFLIFQVSVKMKGQRPLEHD 673



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 9/113 (7%)

Query: 3825 IVSTPPKFITQ-IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS----GHRYR 3879
            +VS PP+ + +  K  TV     V  +CR E +  P   + W    + + S    G R  
Sbjct: 1740 VVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPT--VTWILANQTVVSESSQGSRQA 1797

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
             V   G + L  L +Y  D G Y C A N  G+D     I     P +IL+ +
Sbjct: 1798 VVTVDGTLVLHNLSIY--DRGFYKCVASNPGGQDSLLVKIQVIAAPPVILEQR 1848



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 6/101 (5%)

Query: 2941 PDLKIEWYFNGK-VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            PD  I W   G  VL Q SR K   + G  TL ++ V  +D G Y C A N  G  F   
Sbjct: 601  PDASISWVIPGNNVLYQSSRDKKVLNNG--TLRILQVTPKDQGYYRCVAANPSGVDFLIF 658

Query: 3000 TVYCTSK-DNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQ 3039
             V    K    +E     +G+ GL++  N    L++ PG Q
Sbjct: 659  QVSVKMKGQRPLEHDGETEGS-GLDE-SNPIAHLKEPPGAQ 697



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            T  P  +   K    IK G  A  +   E  GD   ++ WL     + + S I  +    
Sbjct: 2138 TAAPRIRQSNKTNKRIKAGDTAVLDC--EVTGDPKPKIFWLLPSNDMISFS-IDRYTFHA 2194

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
              +LTI  V + D+G Y C A N  G  T    L +V+K  +I
Sbjct: 2195 NGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLI 2237



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%)

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKV-QPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
            G+ + L    TG     + W+  G  V     R+K +  +GT  L IL+  P+D G Y C
Sbjct: 588  GETLDLPCHSTGIPDASISWVIPGNNVLYQSSRDKKVLNNGT--LRILQVTPKDQGYYRC 645

Query: 4587 VAINSAG 4593
            VA N +G
Sbjct: 646  VAANPSG 652



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 65/276 (23%), Positives = 104/276 (37%), Gaps = 38/276 (13%)

Query: 3100 VYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159
            ++ F    L I    ++D GTY C AT+  G     V L   ++     PR     Q   
Sbjct: 1894 LFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVTS--PRIEAASQKRT 1951

Query: 3160 GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-RHSTRIKT-VSDFGFVVLDIAYTQNH 3217
             +  G      C+     +P  +I W    + +     R+ + +  +    L I      
Sbjct: 1952 EVNFGDKLLLNCSAT--GEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEK 2009

Query: 3218 DSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTP 3277
            DSG Y+C A NK G+D     ++      + L+  + D     R+ + L G   Q     
Sbjct: 2010 DSGVYLCVARNKMGDDLILMHVS------LRLKPAKIDHKQYFRK-QVLHGKDFQVDCKA 2062

Query: 3278 SAEP-PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            S  P P+    + D T +     A         DD         +G +     RY  F++
Sbjct: 2063 SGSPVPEISWSLPDGTMINNAMQA---------DD---------SGHRT---RRYTLFNN 2101

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             G +  + +   EE  G+Y C A N LG+D  K +L
Sbjct: 2102 -GTLYFNKVGVAEE--GDYTCYAQNTLGKDEMKVHL 2134



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 3/81 (3%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH---ALMITNVTLSDSGV 462
            G   +  C   G P PE+TW + D  +    + +        H    L+I N   SDSG+
Sbjct: 2543 GAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGI 2602

Query: 463  VTCVARNKSGETAFQCRLNVI 483
              C A+N  G       + VI
Sbjct: 2603 YKCTAKNPLGSDYAATYIQVI 2623



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 7/100 (7%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLV----ECNKYSMRYN 123
            +P+    +Q F+  +   G + + + K  G+P P +SW+     ++    + +    R  
Sbjct: 2036 KPAKIDHKQYFRK-QVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTR 2094

Query: 124  EQT--GDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              T   + +L   ++G  +EG+YTC A+N  G+    V++
Sbjct: 2095 RYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHL 2134



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSR-YKLTYDGMYHFDIPKTRQY 4175
            + +  + G+     C V G+P P ++W+L NG    NG + Y+        F I KT + 
Sbjct: 2345 EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTRE 2404

Query: 4176 DTGK 4179
            D GK
Sbjct: 2405 DAGK 2408



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVL---QSGH 1891
            V + + Q P  +T   G  K   G+S    C  +  P PN  ++W   +G V+   Q   
Sbjct: 2424 VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPN--IKWTMPSGYVVDRPQING 2481

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
            +Y   +D G   +   T Y  D G Y CKA N++G  + ++
Sbjct: 2482 KY-ILHDNGTLVIKEATAY--DRGNYICKAQNSVGHTLITV 2519



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 37/158 (23%), Positives = 69/158 (43%), Gaps = 7/158 (4%)

Query: 1796 TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQ---APRFITQLNG 1852
            T+S LF+ S  +L + +   S     + +  SS    R  V + + +   +PR       
Sbjct: 1890 TNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQK 1949

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQSGHRYRT-SNDFGFAALDILTVY 1910
             T+++ G      C     P P  ++ W    K V+   HR  +  + +   +L I +V 
Sbjct: 1950 RTEVNFGDKLLLNCSATGEPKP--QIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVT 2007

Query: 1911 GEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
             +DSG Y C A N +G  +  + ++++ K + I   Q+
Sbjct: 2008 EKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQY 2045



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 9/107 (8%)

Query: 1840 VNQAPRFITQLNGPTK-LSEGQSAHYECRIEPYPDPNMRVEWYF--NGKVLQSGHRYRTS 1896
            +  APR I Q N   K +  G +A  +C +    DP  ++ W    N  +  S  RY T 
Sbjct: 2137 ITAAPR-IRQSNKTNKRIKAGDTAVLDCEVTG--DPKPKIFWLLPSNDMISFSIDRY-TF 2192

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            +  G  +L I  V   DSGEY C A N  G      +L+V SK  +I
Sbjct: 2193 HANG--SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLI 2237



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 5/101 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTLNDFGFI 3753
            PR     K N  +  G     DC V   GDP  +I W        + S   +T +  G  
Sbjct: 2141 PRIRQSNKTNKRIKAGDTAVLDCEV--TGDPKPKIFWLLPSNDMISFSIDRYTFHANG-- 2196

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            +L I+ +   D+GEY C A N  G  T   K+   +K  ++
Sbjct: 2197 SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLI 2237



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 7/86 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWF--RNEKLIEDSSRITKTHDFGY 2433
            P   Q  +    I+ G TA  DC +   GDP  K+ W    N+ +     R T  H  G 
Sbjct: 2141 PRIRQSNKTNKRIKAGDTAVLDCEV--TGDPKPKIFWLLPSNDMISFSIDRYT-FHANG- 2196

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             S+TI+ V+  D G Y+C A N  G+
Sbjct: 2197 -SLTINKVKLLDSGEYVCVARNPSGD 2221



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 6/137 (4%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHL--TIDWFHNGQKIRAGHRYRTTHD 2163
            GQ+PV LT          G+     C  + I  P++  T+   +   + +   +Y   HD
Sbjct: 2429 GQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY-ILHD 2487

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL 2223
             G + +     Y  D G Y+CKA N +G  + T  + +  +   I + + P  +      
Sbjct: 2488 NGTLVIKEATAY--DRGNYICKAQNSVGHTLITVPVMIVAYPPRITN-RPPRSIVTRTGA 2544

Query: 2224 EAQGHSTRIEVEEPKIS 2240
              Q H   + V +P+I+
Sbjct: 2545 AFQLHCVALGVPKPEIT 2561



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 14/36 (38%), Positives = 18/36 (50%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            +TV  G      CR  G P P V W+L   T+V+ S
Sbjct: 1755 ITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSES 1790



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 17/45 (37%), Positives = 24/45 (53%)

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            +L I  V  +D G+Y+C A N FG D    T+S    P  IL+ +
Sbjct: 1707 TLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRILERR 1751



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS----GHRYRT 1895
            V+  PR + +      +  G +   +CR E  P P   V W    + + S    G R   
Sbjct: 1741 VSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPT--VTWILANQTVVSESSQGSRQAV 1798

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
                G   L  L++Y  D G Y C A N  GQ    +++ V +   +I + + +
Sbjct: 1799 VTVDGTLVLHNLSIY--DRGFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQ 1850



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 956  SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011
            +R  T FN G   L    V V + G YTC A N +G+     +LT++T    I +S
Sbjct: 2093 TRRYTLFNNG--TLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS 2146



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 45/161 (27%), Positives = 60/161 (37%), Gaps = 8/161 (4%)

Query: 3075 TGDQSMVIEWFY-NGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            TGD    I W   +   I  S    T +A G   L I   K  DSG Y C A N  G   
Sbjct: 2166 TGDPKPKIFWLLPSNDMISFSIDRYTFHANGS--LTINKVKLLDSGEYVCVARNPSGDDT 2223

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHN--GQP 3191
               KL+ V K       +T               HF+C       P++      N     
Sbjct: 2224 KMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTA 2283

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              + +RI TV   G   L+I   +  DS +++C A N+ GE
Sbjct: 2284 PYYGSRI-TVHKNG--TLEIRNVRLSDSADFICVARNEGGE 2321



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/125 (26%), Positives = 45/125 (36%), Gaps = 6/125 (4%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G Y C+A N  G   I+V +  V       PR T         + G +    C  + V
Sbjct: 2500 DRGNYICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGV 2555

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV--VLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P++  E   +      S      S+   +   L I   Q  DSG Y C A N  G D+
Sbjct: 2556 PKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDY 2615

Query: 3235 TRATI 3239
                I
Sbjct: 2616 AATYI 2620


>BC045734-1|AAH45734.1|  442|Homo sapiens IGSF10 protein protein.
          Length = 442

 Score = 88.2 bits (209), Expect = 6e-16
 Identities = 105/412 (25%), Positives = 154/412 (37%), Gaps = 50/412 (12%)

Query: 4408 SKPPIFT-----KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-T 4461
            SKPP+       + +       H +  F+   +G P P + W   +     +P +    T
Sbjct: 51   SKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRIT 110

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
                  L IR V + DSA F  VA N GG +     L V E  R+      P       +
Sbjct: 111  VHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRR------PTFRNPFNE 164

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKVQ--PDIRNKILEEDGTYTLLILEAYP 4578
             +    G+   L+  V G  P ++ W L NG +    P     ++  +G++  +I +   
Sbjct: 165  KIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSF--IISKTTR 222

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
            +D+GKY C A N  G      E +V L   + KP   T A    P  ++ +       G+
Sbjct: 223  EDAGKYRCAARNKVGY----IEKLVILEIGQ-KPVILTYA----PGTVKGI------SGE 267

Query: 4639 AIEFSCKIVGKPLPTVQW-----YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            ++   C   G P P ++W     Y  D+     KY       D  TL I EA   D G+Y
Sbjct: 268  SLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI----LHDNGTLVIKEATAYDRGNY 323

Query: 4694 KCVAYNSAGRVTVAAKLK-VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
             C A NS G   +   +  V  P +  N P     R IV   G   Q         KP I
Sbjct: 324  ICKAQNSVGHTLITVPVMIVAYPPRITNRPP----RSIVTRTGAAFQLHCVALGVPKPEI 379

Query: 4753 QWLREGALIPETPDFQMIHEGN----NAVLLIGNTYEEDTGTFTCRATTAAG 4800
             W      +  T   +  H          L+I N    D+G + C A    G
Sbjct: 380  TWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 431



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 55/164 (33%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 411 FDCRVTGRPYPEVTWFINDRQIRDD--YNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
           FDCR  G P PEV W + D        Y  +I V+++G   L I NV LSDS    CVAR
Sbjct: 78  FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 135

Query: 469 NKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTPTPRITW-QK 526
           N+ GE+    +L V+  E +  P F   F+   V + G+   LN    G P P I W   
Sbjct: 136 NEGGESVLVVQLEVL--EMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILP 193

Query: 527 DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           +G      P+   +      +  I +    DA  Y+C A+N  G
Sbjct: 194 NGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 237



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 58/200 (29%), Positives = 90/200 (45%), Gaps = 20/200 (10%)

Query: 382 RIEISEKALAPQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWFI--NDRQIRDDYNH 438
           ++E+ E    P F     ++ V + GK T  +C V G P PE+ W +    R      ++
Sbjct: 146 QLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSY 205

Query: 439 KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVER 496
           + L+  + N + +I+  T  D+G   C ARNK G       L + +K  ++  AP  V+ 
Sbjct: 206 QYLI--ASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKG 263

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR----IHTDGGASTLDIPR 552
            S      GE + L+  + G P P I W      ++  P++     +H +G   TL I  
Sbjct: 264 IS------GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNG---TLVIKE 314

Query: 553 AKASDAAWYQCTAQNVAGST 572
           A A D   Y C AQN  G T
Sbjct: 315 ATAYDRGNYICKAQNSVGHT 334



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 74/286 (25%), Positives = 112/286 (39%), Gaps = 33/286 (11%)

Query: 4435 DGEPLPLIKWYRENFP-IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            DG P P I W   N     N P    +  ++    II +   ED+  +   A N+ G  +
Sbjct: 181  DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIE 240

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGK 4552
                L + +K         P   T     V   SG+ + L     G    ++ W + +G 
Sbjct: 241  KLVILEIGQK---------PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGY 291

Query: 4553 KV-QPDIRNK-ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
             V +P I  K IL ++GT  L+I EA   D G Y C A NS G        ++++P    
Sbjct: 292  VVDRPQINGKYILHDNGT--LVIKEATAYDRGNYICKAQNSVGHT------LITVPVMIV 343

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
               P  +  N PP  I      +   G A +  C  +G P P + W   D  +  +   +
Sbjct: 344  AYPP--RITNRPPRSI------VTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKE 395

Query: 4671 MSRTADEY----TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +  +++     TL I      D G YKC A N  G    A  ++V
Sbjct: 396  RTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 441



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 87/365 (23%), Positives = 137/365 (37%), Gaps = 45/365 (12%)

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
            +TF     L I +V + DS  +  VA N  G       L V  K         PP     
Sbjct: 9    YTFHANGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSK---------PPLINGL 59

Query: 4520 AQNVNVTSGQLVR-----LDTKVTGTKPIDVYWLK--NGKKVQPDIRNKI-LEEDGTYTL 4571
              N  V     VR      D +  GT   +V W+   N     P   ++I + ++GT  L
Sbjct: 60   YTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--L 117

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      DS  + CVA N  GE    +  VV L   +   +P  +          P  +
Sbjct: 118  EIRNVRLSDSADFICVARNEGGE----SVLVVQLEVLEMLRRPTFR---------NPFNE 164

Query: 4632 KIVAE-GQAIEFSCKIVGKPLPTVQWY--KGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            KIVA+ G++   +C + G P P + W    G +     + +Q    A   +  IS+   E
Sbjct: 165  KIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQY-LIASNGSFIISKTTRE 223

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            D G Y+C A N  G +    KL + +  Q   +    P   +    G+            
Sbjct: 224  DAGKYRCAARNKVGYI---EKLVILEIGQKPVILTYAP-GTVKGISGESLSLHCVSDGIP 279

Query: 4749 KPTIQWLREGALIPETPDFQ---MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
            KP I+W      + + P      ++H+  N  L+I      D G + C+A  + G    +
Sbjct: 280  KPNIKWTMPSGYVVDRPQINGKYILHD--NGTLVIKEATAYDRGNYICKAQNSVGHTLIT 337

Query: 4806 AKLVV 4810
              +++
Sbjct: 338  VPVMI 342



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 52/221 (23%), Positives = 80/221 (36%), Gaps = 10/221 (4%)

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE-----FSCKIVGKPLPTVQ 4655
            CV   P+  D    +    + PP I     ++ V +  A+      F C+  G P P V 
Sbjct: 32   CVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVM 91

Query: 4656 WYKGDKLIKPSKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            W   D +   + Y+    T  +  TL I      D  D+ CVA N  G   +  +L+V +
Sbjct: 92   WIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLE 151

Query: 4715 PDQADNLPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQW-LREGALIPETPDFQMIHE 4772
              +        P  + +V + G+       +     P I W L  G      P       
Sbjct: 152  MLRRPTFR--NPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLI 209

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +N   +I  T  ED G + C A    G +E    L +  K
Sbjct: 210  ASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQK 250



 Score = 61.7 bits (143), Expect = 6e-08
 Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 10/138 (7%)

Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER--FSTLNVRE 504
           N +L I  V L DSG   CVARN SG+     +L+V+ K  ++   +  R       VR 
Sbjct: 14  NGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRH 73

Query: 505 GEPVVLNARAVGTPTPRITW-QKDGVPIIP---NPELRIHTDGGASTLDIPRAKASDAAW 560
            +    + RA GTP+P + W   D + +        + +H +G   TL+I   + SD+A 
Sbjct: 74  SKK-HFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG---TLEIRNVRLSDSAD 129

Query: 561 YQCTAQNVAGSTATRARL 578
           + C A+N  G +    +L
Sbjct: 130 FICVARNEGGESVLVVQL 147



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 46/174 (26%), Positives = 73/174 (41%), Gaps = 15/174 (8%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVTLSDSGVV 463
           G+     C   G P P + W +    +  R   N K +++++G   L+I   T  D G  
Sbjct: 266 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 323

Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRI 522
            C A+N  G T     + ++       P+   R   ++  R G    L+  A+G P P I
Sbjct: 324 ICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEI 379

Query: 523 TWQKDGVPIIPNPELRIHTDGGAS-----TLDIPRAKASDAAWYQCTAQNVAGS 571
           TW+     ++     +  T G        TL I   + SD+  Y+CTA+N  GS
Sbjct: 380 TWEMPDHSLLSTAS-KERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 432



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 265 PPKIAQKP-RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS----NKHEIITTHN 319
           PP+I  +P R+   + GA  Q      G P+P +TW      L+++      H     H 
Sbjct: 346 PPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHL 405

Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
             TL ++N Q SDSG Y   A+NP G    + Y+ V
Sbjct: 406 QGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 441



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 16/125 (12%)

Query: 3113 TKTT--DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ-NIEGLKDGQSAHF 3169
            +KTT  D+G Y C A NK G  E  V LE      GQKP   T+    ++G+  G+S   
Sbjct: 218  SKTTREDAGKYRCAARNKVGYIEKLVILEI-----GQKPVILTYAPGTVKGI-SGESLSL 271

Query: 3170 ECTVVPVDDPDMK---IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             C    +  P++K      Y   +P  +   I  + D G +V+  A    +D G Y+C+A
Sbjct: 272  HCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI--LHDNGTLVIKEATA--YDRGNYICKA 327

Query: 3227 YNKYG 3231
             N  G
Sbjct: 328  QNSVG 332



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 11/128 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   + +DS  + C A N+ G++ + V+LE ++  +  +P F          + G+S 
Sbjct: 117  LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR--RPTFRNPFNEKIVAQLGKST 174

Query: 3168 HFECTVVPVDDPDMKIEW-YHNGQPMRH---STRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
               C+V    +P  +I W   NG    +   S +    S+  F+   I+ T   D+G+Y 
Sbjct: 175  ALNCSV--DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFI---ISKTTREDAGKYR 229

Query: 3224 CRAYNKYG 3231
            C A NK G
Sbjct: 230  CAARNKVG 237



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 55/229 (24%), Positives = 81/229 (35%), Gaps = 16/229 (6%)

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAI----CSVYIQPE--GXXXXXXXXXXXXXYRHVS 183
           SL I ++   D GEY C ARN  G+        V  +P                  RH  
Sbjct: 16  SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSK 75

Query: 184 ETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESI--T 241
           +  + +A GT             +  T     S     K  T E R +R     + I   
Sbjct: 76  KHFDCRAEGTPSPEVMWI-MPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVA 134

Query: 242 KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRVTW 299
           +   GES + +  E+   L  +  P   + P N K+  Q G        + GNP P + W
Sbjct: 135 RNEGGESVLVVQLEV---LEMLRRPTF-RNPFNEKIVAQLGKSTALNCSVDGNPPPEIIW 190

Query: 300 F-KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
              NG R  N  +       ++ +  +  T + D+G Y   A N  G I
Sbjct: 191 ILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYI 239



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 3/81 (3%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH---ALMITNVTLSDSGV 462
           G   +  C   G P PE+TW + D  +    + +        H    L+I N   SDSG+
Sbjct: 362 GAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGI 421

Query: 463 VTCVARNKSGETAFQCRLNVI 483
             C A+N  G       + VI
Sbjct: 422 YKCTAKNPLGSDYAATYIQVI 442



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/97 (22%), Positives = 40/97 (41%), Gaps = 6/97 (6%)

Query: 71  PPIFEQIFKN-----ARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           PP+   ++ N     A   +     F+ +  G P+P V W       +    Y  R    
Sbjct: 53  PPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVH 112

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
               +L I+ +   D  ++ C ARN+ GE++  V ++
Sbjct: 113 KNG-TLEIRNVRLSDSADFICVARNEGGESVLVVQLE 148



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSR-YKLTYDGMYHFDIPKTRQY 4175
            + +  + G+     C V G+P P ++W+L NG    NG + Y+        F I KT + 
Sbjct: 164  EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTRE 223

Query: 4176 DTGK 4179
            D GK
Sbjct: 224  DAGK 227



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVL---QSGH 1891
            V + + Q P  +T   G  K   G+S    C  +  P PN  ++W   +G V+   Q   
Sbjct: 243  VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPN--IKWTMPSGYVVDRPQING 300

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
            +Y   +D G   +   T Y  D G Y CKA N++G  + ++
Sbjct: 301  KY-ILHDNGTLVIKEATAY--DRGNYICKAQNSVGHTLITV 338



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 6/137 (4%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHL--TIDWFHNGQKIRAGHRYRTTHD 2163
            GQ+PV LT          G+     C  + I  P++  T+   +   + +   +Y   HD
Sbjct: 248  GQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY-ILHD 306

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL 2223
             G + +     Y  D G Y+CKA N +G  + T  + +  +   I + + P  +      
Sbjct: 307  NGTLVIKEATAY--DRGNYICKAQNSVGHTLITVPVMIVAYPPRITN-RPPRSIVTRTGA 363

Query: 2224 EAQGHSTRIEVEEPKIS 2240
              Q H   + V +P+I+
Sbjct: 364  AFQLHCVALGVPKPEIT 380



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/125 (26%), Positives = 45/125 (36%), Gaps = 6/125 (4%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G Y C+A N  G   I+V +  V       PR T         + G +    C  + V
Sbjct: 319  DRGNYICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGV 374

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV--VLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P++  E   +      S      S+   +   L I   Q  DSG Y C A N  G D+
Sbjct: 375  PKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDY 434

Query: 3235 TRATI 3239
                I
Sbjct: 435  AATYI 439


>AK098838-1|BAC05429.1|  399|Homo sapiens protein ( Homo sapiens cDNA
            FLJ25972 fis, clone TST05664. ).
          Length = 399

 Score = 88.2 bits (209), Expect = 6e-16
 Identities = 105/412 (25%), Positives = 154/412 (37%), Gaps = 50/412 (12%)

Query: 4408 SKPPIFT-----KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-T 4461
            SKPP+       + +       H +  F+   +G P P + W   +     +P +    T
Sbjct: 8    SKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRIT 67

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
                  L IR V + DSA F  VA N GG +     L V E  R+      P       +
Sbjct: 68   VHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRR------PTFRNPFNE 121

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKVQ--PDIRNKILEEDGTYTLLILEAYP 4578
             +    G+   L+  V G  P ++ W L NG +    P     ++  +G++  +I +   
Sbjct: 122  KIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSF--IISKTTR 179

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
            +D+GKY C A N  G      E +V L   + KP   T A    P  ++ +       G+
Sbjct: 180  EDAGKYRCAARNKVGY----IEKLVILEIGQ-KPVILTYA----PGTVKGI------SGE 224

Query: 4639 AIEFSCKIVGKPLPTVQW-----YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            ++   C   G P P ++W     Y  D+     KY       D  TL I EA   D G+Y
Sbjct: 225  SLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI----LHDNGTLVIKEATAYDRGNY 280

Query: 4694 KCVAYNSAGRVTVAAKLK-VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
             C A NS G   +   +  V  P +  N P     R IV   G   Q         KP I
Sbjct: 281  ICKAQNSVGHTLITVPVMIVAYPPRITNRPP----RSIVTRTGAAFQLHCVALGVPKPEI 336

Query: 4753 QWLREGALIPETPDFQMIHEGN----NAVLLIGNTYEEDTGTFTCRATTAAG 4800
             W      +  T   +  H          L+I N    D+G + C A    G
Sbjct: 337  TWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 388



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 55/164 (33%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 411 FDCRVTGRPYPEVTWFINDRQIRDD--YNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
           FDCR  G P PEV W + D        Y  +I V+++G   L I NV LSDS    CVAR
Sbjct: 35  FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 92

Query: 469 NKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTPTPRITW-QK 526
           N+ GE+    +L V+  E +  P F   F+   V + G+   LN    G P P I W   
Sbjct: 93  NEGGESVLVVQLEVL--EMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILP 150

Query: 527 DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           +G      P+   +      +  I +    DA  Y+C A+N  G
Sbjct: 151 NGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 194



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 58/200 (29%), Positives = 90/200 (45%), Gaps = 20/200 (10%)

Query: 382 RIEISEKALAPQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWFI--NDRQIRDDYNH 438
           ++E+ E    P F     ++ V + GK T  +C V G P PE+ W +    R      ++
Sbjct: 103 QLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSY 162

Query: 439 KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVER 496
           + L+  + N + +I+  T  D+G   C ARNK G       L + +K  ++  AP  V+ 
Sbjct: 163 QYLI--ASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKG 220

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR----IHTDGGASTLDIPR 552
            S      GE + L+  + G P P I W      ++  P++     +H +G   TL I  
Sbjct: 221 IS------GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNG---TLVIKE 271

Query: 553 AKASDAAWYQCTAQNVAGST 572
           A A D   Y C AQN  G T
Sbjct: 272 ATAYDRGNYICKAQNSVGHT 291



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 74/286 (25%), Positives = 112/286 (39%), Gaps = 33/286 (11%)

Query: 4435 DGEPLPLIKWYRENFP-IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            DG P P I W   N     N P    +  ++    II +   ED+  +   A N+ G  +
Sbjct: 138  DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIE 197

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGK 4552
                L + +K         P   T     V   SG+ + L     G    ++ W + +G 
Sbjct: 198  KLVILEIGQK---------PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGY 248

Query: 4553 KV-QPDIRNK-ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
             V +P I  K IL ++GT  L+I EA   D G Y C A NS G        ++++P    
Sbjct: 249  VVDRPQINGKYILHDNGT--LVIKEATAYDRGNYICKAQNSVGHT------LITVPVMIV 300

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
               P  +  N PP  I      +   G A +  C  +G P P + W   D  +  +   +
Sbjct: 301  AYPP--RITNRPPRSI------VTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKE 352

Query: 4671 MSRTADEY----TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +  +++     TL I      D G YKC A N  G    A  ++V
Sbjct: 353  RTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 398



 Score = 61.3 bits (142), Expect = 8e-08
 Identities = 43/175 (24%), Positives = 64/175 (36%), Gaps = 5/175 (2%)

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNS 4700
            F C+  G P P V W   D +   + Y+    T  +  TL I      D  D+ CVA N 
Sbjct: 35   FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNE 94

Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE-GQPAQFKTQITSKIKPTIQW-LREG 4758
             G   +  +L+V +  +        P  + +V + G+       +     P I W L  G
Sbjct: 95   GGESVLVVQLEVLEMLRRPTFR--NPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNG 152

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                  P        +N   +I  T  ED G + C A    G +E    L +  K
Sbjct: 153  TRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQK 207



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 67/286 (23%), Positives = 113/286 (39%), Gaps = 31/286 (10%)

Query: 4534 DTKVTGTKPIDVYWLK--NGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            D +  GT   +V W+   N     P   ++I + ++GT  L I      DS  + CVA N
Sbjct: 36   DCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVARN 93

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFSCKIVGK 4649
              GE    +  VV L   +   +P  +          P  +KIVA+ G++   +C + G 
Sbjct: 94   EGGE----SVLVVQLEVLEMLRRPTFR---------NPFNEKIVAQLGKSTALNCSVDGN 140

Query: 4650 PLPTVQWY--KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            P P + W    G +     + +Q    A   +  IS+   ED G Y+C A N  G +   
Sbjct: 141  PPPEIIWILPNGTRFSNGPQSYQY-LIASNGSFIISKTTREDAGKYRCAARNKVGYI--- 196

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
             KL + +  Q   +    P   +    G+            KP I+W      + + P  
Sbjct: 197  EKLVILEIGQKPVILTYAP-GTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQI 255

Query: 4768 Q---MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                ++H+  N  L+I      D G + C+A  + G    +  +++
Sbjct: 256  NGKYILHD--NGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMI 299



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 46/174 (26%), Positives = 73/174 (41%), Gaps = 15/174 (8%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVTLSDSGVV 463
           G+     C   G P P + W +    +  R   N K +++++G   L+I   T  D G  
Sbjct: 223 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 280

Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRI 522
            C A+N  G T     + ++       P+   R   ++  R G    L+  A+G P P I
Sbjct: 281 ICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEI 336

Query: 523 TWQKDGVPIIPNPELRIHTDGGAS-----TLDIPRAKASDAAWYQCTAQNVAGS 571
           TW+     ++     +  T G        TL I   + SD+  Y+CTA+N  GS
Sbjct: 337 TWEMPDHSLLSTAS-KERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 389



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 265 PPKIAQKP-RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS----NKHEIITTHN 319
           PP+I  +P R+   + GA  Q      G P+P +TW      L+++      H     H 
Sbjct: 303 PPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHL 362

Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
             TL ++N Q SDSG Y   A+NP G    + Y+ V
Sbjct: 363 QGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 398



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 16/125 (12%)

Query: 3113 TKTT--DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ-NIEGLKDGQSAHF 3169
            +KTT  D+G Y C A NK G  E  V LE      GQKP   T+    ++G+  G+S   
Sbjct: 175  SKTTREDAGKYRCAARNKVGYIEKLVILEI-----GQKPVILTYAPGTVKGI-SGESLSL 228

Query: 3170 ECTVVPVDDPDMK---IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             C    +  P++K      Y   +P  +   I  + D G +V+  A    +D G Y+C+A
Sbjct: 229  HCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI--LHDNGTLVIKEATA--YDRGNYICKA 284

Query: 3227 YNKYG 3231
             N  G
Sbjct: 285  QNSVG 289



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 11/128 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   + +DS  + C A N+ G++ + V+LE ++  +  +P F          + G+S 
Sbjct: 74   LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR--RPTFRNPFNEKIVAQLGKST 131

Query: 3168 HFECTVVPVDDPDMKIEW-YHNGQPMRH---STRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
               C+V    +P  +I W   NG    +   S +    S+  F+   I+ T   D+G+Y 
Sbjct: 132  ALNCSV--DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFI---ISKTTREDAGKYR 186

Query: 3224 CRAYNKYG 3231
            C A NK G
Sbjct: 187  CAARNKVG 194



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 285 FQVQLSGNPRPRVTWFKNGQRLINSNKH-EIITTHNHTTLRVRNTQKSDSGHYTLLAENP 343
           F  +  G P P V W       + +  +   IT H + TL +RN + SDS  +  +A N 
Sbjct: 35  FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNE 94

Query: 344 NG 345
            G
Sbjct: 95  GG 96



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 3/81 (3%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH---ALMITNVTLSDSGV 462
           G   +  C   G P PE+TW + D  +    + +        H    L+I N   SDSG+
Sbjct: 319 GAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGI 378

Query: 463 VTCVARNKSGETAFQCRLNVI 483
             C A+N  G       + VI
Sbjct: 379 YKCTAKNPLGSDYAATYIQVI 399



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 22/97 (22%), Positives = 40/97 (41%), Gaps = 6/97 (6%)

Query: 71  PPIFEQIFKN-----ARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           PP+   ++ N     A   +     F+ +  G P+P V W       +    Y  R    
Sbjct: 10  PPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVH 69

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
               +L I+ +   D  ++ C ARN+ GE++  V ++
Sbjct: 70  KNG-TLEIRNVRLSDSADFICVARNEGGESVLVVQLE 105



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSR-YKLTYDGMYHFDIPKTRQY 4175
            + +  + G+     C V G+P P ++W+L NG    NG + Y+        F I KT + 
Sbjct: 121  EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTRE 180

Query: 4176 DTGK 4179
            D GK
Sbjct: 181  DAGK 184



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVL---QSGH 1891
            V + + Q P  +T   G  K   G+S    C  +  P PN  ++W   +G V+   Q   
Sbjct: 200  VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPN--IKWTMPSGYVVDRPQING 257

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
            +Y   +D G   +   T Y  D G Y CKA N++G  + ++
Sbjct: 258  KY-ILHDNGTLVIKEATAY--DRGNYICKAQNSVGHTLITV 295



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 10/106 (9%)

Query: 479 RLNVIEKEQVVAPKFVER--FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP- 535
           +L+V+ K  ++   +  R       VR  +    + RA GTP+P + W       +  P 
Sbjct: 3   KLDVVSKPPLINGLYTNRTVIKATAVRHSKKH-FDCRAEGTPSPEVMWIMPDNIFLTAPY 61

Query: 536 ---ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               + +H +G   TL+I   + SD+A + C A+N  G +    +L
Sbjct: 62  YGSRITVHKNG---TLEIRNVRLSDSADFICVARNEGGESVLVVQL 104



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 3/81 (3%)

Query: 270 QKPRNSKL--QEGADAQFQVQLSGNPRPRVTWF-KNGQRLINSNKHEIITTHNHTTLRVR 326
           + P N K+  Q G        + GNP P + W   NG R  N  +       ++ +  + 
Sbjct: 116 RNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIIS 175

Query: 327 NTQKSDSGHYTLLAENPNGCI 347
            T + D+G Y   A N  G I
Sbjct: 176 KTTREDAGKYRCAARNKVGYI 196



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 6/137 (4%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHL--TIDWFHNGQKIRAGHRYRTTHD 2163
            GQ+PV LT          G+     C  + I  P++  T+   +   + +   +Y   HD
Sbjct: 205  GQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY-ILHD 263

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL 2223
             G + +     Y  D G Y+CKA N +G  + T  + +  +   I + + P  +      
Sbjct: 264  NGTLVIKEATAY--DRGNYICKAQNSVGHTLITVPVMIVAYPPRITN-RPPRSIVTRTGA 320

Query: 2224 EAQGHSTRIEVEEPKIS 2240
              Q H   + V +P+I+
Sbjct: 321  AFQLHCVALGVPKPEIT 337



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/125 (26%), Positives = 45/125 (36%), Gaps = 6/125 (4%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G Y C+A N  G   I+V +  V       PR T         + G +    C  + V
Sbjct: 276  DRGNYICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGV 331

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV--VLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P++  E   +      S      S+   +   L I   Q  DSG Y C A N  G D+
Sbjct: 332  PKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDY 391

Query: 3235 TRATI 3239
                I
Sbjct: 392  AATYI 396


>AK093069-1|BAC04042.1|  650|Homo sapiens protein ( Homo sapiens cDNA
            FLJ35750 fis, clone TESTI2004539, weakly similar to Homo
            sapiens adlican mRNA. ).
          Length = 650

 Score = 88.2 bits (209), Expect = 6e-16
 Identities = 107/413 (25%), Positives = 155/413 (37%), Gaps = 52/413 (12%)

Query: 4408 SKPPIFT-----KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-T 4461
            SKPP+       + +       H +  F+   +G P P + W   +     +P +    T
Sbjct: 259  SKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRIT 318

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
                  L IR V + DSA F  VA N GG +     L V E  R+       P+F     
Sbjct: 319  VHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRR-------PTFRNPFN 371

Query: 4522 NVNVTS-GQLVRLDTKVTGTKPIDVYW-LKNGKKVQ--PDIRNKILEEDGTYTLLILEAY 4577
               V   G+   L+  V G  P ++ W L NG +    P     ++  +G++  +I +  
Sbjct: 372  EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSF--IISKTT 429

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
             +D+GKY C A N  G      E +V L   + KP   T A    P  ++ +       G
Sbjct: 430  REDAGKYRCAARNKVGYI----EKLVILEIGQ-KPVILTYA----PGTVKGIS------G 474

Query: 4638 QAIEFSCKIVGKPLPTVQW-----YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            +++   C   G P P ++W     Y  D+     KY       D  TL I EA   D G+
Sbjct: 475  ESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI----LHDNGTLVIKEATAYDRGN 530

Query: 4693 YKCVAYNSAGRVTVAAKLK-VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            Y C A NS G   +   +  V  P +  N P     R IV   G   Q         KP 
Sbjct: 531  YICKAQNSVGHTLITVPVMIVAYPPRITNRPP----RSIVTRTGAAFQLHCVALGVPKPE 586

Query: 4752 IQWLREGALIPETPDFQMIHEGN----NAVLLIGNTYEEDTGTFTCRATTAAG 4800
            I W      +  T   +  H          L+I N    D+G + C A    G
Sbjct: 587  ITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 639



 Score = 81.8 bits (193), Expect = 6e-14
 Identities = 55/164 (33%), Positives = 75/164 (45%), Gaps = 8/164 (4%)

Query: 411 FDCRVTGRPYPEVTWFINDRQIRDD--YNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
           FDCR  G P PEV W + D        Y  +I V+++G   L I NV LSDS    CVAR
Sbjct: 286 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 343

Query: 469 NKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTPTPRITW-QK 526
           N+ GE+    +L V+  E +  P F   F+   V + G+   LN    G P P I W   
Sbjct: 344 NEGGESVLVVQLEVL--EMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILP 401

Query: 527 DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           +G      P+   +      +  I +    DA  Y+C A+N  G
Sbjct: 402 NGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 445



 Score = 77.4 bits (182), Expect = 1e-12
 Identities = 79/324 (24%), Positives = 135/324 (41%), Gaps = 38/324 (11%)

Query: 263 VSPPKIAQKPRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           + P KI  K    K +  G D Q   + SG+P P ++W      +IN+            
Sbjct: 62  LKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAM---------- 111

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
                  Q  DSGH T      N   +    + V        +   + Y  +T  ++ E 
Sbjct: 112 -------QADDSGHRTRRYTLFNNGTLYFNKVGVAE------EGDYTCYAQNTLGKD-EM 157

Query: 382 RIEISEKALAPQFVKVCQ-DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
           ++ ++    AP+  +  + ++ +  G     DC VTG P P++ W +    +      + 
Sbjct: 158 KVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRY 217

Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER--FS 498
             + +G+  L I  V L DSG   CVARN SG+     +L+V+ K  ++   +  R    
Sbjct: 218 TFHANGS--LTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIK 275

Query: 499 TLNVREGEPVVLNARAVGTPTPRITW-QKDGVPIIP---NPELRIHTDGGASTLDIPRAK 554
              VR  +    + RA GTP+P + W   D + +        + +H +G   TL+I   +
Sbjct: 276 ATAVRHSKK-HFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG---TLEIRNVR 331

Query: 555 ASDAAWYQCTAQNVAGSTATRARL 578
            SD+A + C A+N  G +    +L
Sbjct: 332 LSDSADFICVARNEGGESVLVVQL 355



 Score = 75.8 bits (178), Expect = 4e-12
 Identities = 94/426 (22%), Positives = 155/426 (36%), Gaps = 46/426 (10%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP---DFQIH- 4460
            +KP+K  I  K+    +V   +  + + +  G P+P I W   +  + N+    D   H 
Sbjct: 62   LKPAK--IDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHR 119

Query: 4461 ----TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF 4516
                T      L   +V V +   +   A+N  G  +   +L V     + R        
Sbjct: 120  TRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS------ 173

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL-KNGKKVQPDIRNKILEEDGTYTLLILE 4575
                 N  + +G    LD +VTG     ++WL  +   +   I       +G+ T+  ++
Sbjct: 174  --NKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK 231

Query: 4576 AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA 4635
                DSG+Y CVA N +G+               D    +    + PP I     ++ V 
Sbjct: 232  LL--DSGEYVCVARNPSGD---------------DTKMYKLDVVSKPPLINGLYTNRTVI 274

Query: 4636 EGQAIE-----FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY-TLRISEAFPED 4689
            +  A+      F C+  G P P V W   D +   + Y+    T  +  TL I      D
Sbjct: 275  KATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSD 334

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE-GQPAQFKTQITSKI 4748
              D+ CVA N  G   +  +L+V +  +        P  + +V + G+       +    
Sbjct: 335  SADFICVARNEGGESVLVVQLEVLEMLRRPTFR--NPFNEKIVAQLGKSTALNCSVDGNP 392

Query: 4749 KPTIQW-LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             P I W L  G      P        +N   +I  T  ED G + C A    G +E    
Sbjct: 393  PPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVI 452

Query: 4808 LVVKSK 4813
            L +  K
Sbjct: 453  LEIGQK 458



 Score = 74.5 bits (175), Expect = 8e-12
 Identities = 98/406 (24%), Positives = 153/406 (37%), Gaps = 50/406 (12%)

Query: 4421 RVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSILIIRQVFVEDS 4478
            R+   + A  + E  G+P P I W     P  +   F I  +TF     L I +V + DS
Sbjct: 179  RIKAGDTAVLDCEVTGDPKPKIFWL---LPSNDMISFSIDRYTFHANGSLTINKVKLLDS 235

Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR-----L 4533
              +  VA N  G       L V  K         PP       N  V     VR      
Sbjct: 236  GEYVCVARNPSGDDTKMYKLDVVSK---------PPLINGLYTNRTVIKATAVRHSKKHF 286

Query: 4534 DTKVTGTKPIDVYWLK--NGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            D +  GT   +V W+   N     P   ++I + ++GT  L I      DS  + CVA N
Sbjct: 287  DCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVARN 344

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFSCKIVGK 4649
              GE    +  VV L   +   +P  +          P  +KIVA+ G++   +C + G 
Sbjct: 345  EGGE----SVLVVQLEVLEMLRRPTFR---------NPFNEKIVAQLGKSTALNCSVDGN 391

Query: 4650 PLPTVQWY--KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            P P + W    G +     + +Q    A   +  IS+   ED G Y+C A N  G +   
Sbjct: 392  PPPEIIWILPNGTRFSNGPQSYQY-LIASNGSFIISKTTREDAGKYRCAARNKVGYI--- 447

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
             KL + +  Q   +    P   +    G+            KP I+W      + + P  
Sbjct: 448  EKLVILEIGQKPVILTYAP-GTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQI 506

Query: 4768 Q---MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                ++H+  N  L+I      D G + C+A  + G    +  +++
Sbjct: 507  NGKYILHD--NGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMI 550



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 58/200 (29%), Positives = 90/200 (45%), Gaps = 20/200 (10%)

Query: 382 RIEISEKALAPQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWFI--NDRQIRDDYNH 438
           ++E+ E    P F     ++ V + GK T  +C V G P PE+ W +    R      ++
Sbjct: 354 QLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSY 413

Query: 439 KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVER 496
           + L+  + N + +I+  T  D+G   C ARNK G       L + +K  ++  AP  V+ 
Sbjct: 414 QYLI--ASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKG 471

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR----IHTDGGASTLDIPR 552
            S      GE + L+  + G P P I W      ++  P++     +H +G   TL I  
Sbjct: 472 IS------GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNG---TLVIKE 522

Query: 553 AKASDAAWYQCTAQNVAGST 572
           A A D   Y C AQN  G T
Sbjct: 523 ATAYDRGNYICKAQNSVGHT 542



 Score = 66.9 bits (156), Expect = 2e-09
 Identities = 74/286 (25%), Positives = 112/286 (39%), Gaps = 33/286 (11%)

Query: 4435 DGEPLPLIKWYRENFP-IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            DG P P I W   N     N P    +  ++    II +   ED+  +   A N+ G  +
Sbjct: 389  DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIE 448

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGK 4552
                L + +K         P   T     V   SG+ + L     G    ++ W + +G 
Sbjct: 449  KLVILEIGQK---------PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGY 499

Query: 4553 KV-QPDIRNK-ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD 4610
             V +P I  K IL ++GT  L+I EA   D G Y C A NS G        ++++P    
Sbjct: 500  VVDRPQINGKYILHDNGT--LVIKEATAYDRGNYICKAQNSVGHT------LITVPVMIV 551

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
               P  +  N PP  I      +   G A +  C  +G P P + W   D  +  +   +
Sbjct: 552  AYPP--RITNRPPRSI------VTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKE 603

Query: 4671 MSRTADEY----TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             +  +++     TL I      D G YKC A N  G    A  ++V
Sbjct: 604  RTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 649



 Score = 58.0 bits (134), Expect = 8e-07
 Identities = 46/174 (26%), Positives = 73/174 (41%), Gaps = 15/174 (8%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVTLSDSGVV 463
           G+     C   G P P + W +    +  R   N K +++++G   L+I   T  D G  
Sbjct: 474 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 531

Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRI 522
            C A+N  G T     + ++       P+   R   ++  R G    L+  A+G P P I
Sbjct: 532 ICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEI 587

Query: 523 TWQKDGVPIIPNPELRIHTDGGAS-----TLDIPRAKASDAAWYQCTAQNVAGS 571
           TW+     ++     +  T G        TL I   + SD+  Y+CTA+N  GS
Sbjct: 588 TWEMPDHSLLSTAS-KERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 640



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 39/140 (27%), Positives = 60/140 (42%), Gaps = 11/140 (7%)

Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
           N +L I +VT  DSGV  CVARNK G+      +++  K   +  K   ++    V  G+
Sbjct: 25  NGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHK---QYFRKQVLHGK 81

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNP--------ELRIHTDGGASTLDIPRAKASDA 558
              ++ +A G+P P I+W      +I N           R +T     TL   +   ++ 
Sbjct: 82  DFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEE 141

Query: 559 AWYQCTAQNVAGSTATRARL 578
             Y C AQN  G    +  L
Sbjct: 142 GDYTCYAQNTLGKDEMKVHL 161



 Score = 51.2 bits (117), Expect = 9e-05
 Identities = 66/291 (22%), Positives = 105/291 (36%), Gaps = 23/291 (7%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE--CNKYSMRYNEQTG 127
           +P I +    N R   G  A  + ++ G+P P + W      ++    ++Y+   N    
Sbjct: 167 APRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANG--- 223

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAI----CSVYIQPE--GXXXXXXXXXXXXXYRH 181
             SL I ++   D GEY C ARN  G+        V  +P                  RH
Sbjct: 224 --SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRH 281

Query: 182 VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE--S 239
             +  + +A GT             +  T     S     K  T E R +R     +   
Sbjct: 282 SKKHFDCRAEGTPS-PEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFIC 340

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRV 297
           + +   GES + +  E+   L  +  P   + P N K+  Q G        + GNP P +
Sbjct: 341 VARNEGGESVLVVQLEV---LEMLRRPTF-RNPFNEKIVAQLGKSTALNCSVDGNPPPEI 396

Query: 298 TW-FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
            W   NG R  N  +       ++ +  +  T + D+G Y   A N  G I
Sbjct: 397 IWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYI 447



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 42/142 (29%), Positives = 58/142 (40%), Gaps = 7/142 (4%)

Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF 3151
            ++ HR R    F    L        + G Y+C A N  G+ E+ V L  +  +    PR 
Sbjct: 115  DSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAA----PRI 170

Query: 3152 TTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDI 3211
                +  + +K G +A  +C V    DP  KI W      M  S  I   +      L I
Sbjct: 171  RQSNKTNKRIKAGDTAVLDCEV--TGDPKPKIFWLLPSNDM-ISFSIDRYTFHANGSLTI 227

Query: 3212 AYTQNHDSGEYVCRAYNKYGED 3233
               +  DSGEYVC A N  G+D
Sbjct: 228  NKVKLLDSGEYVCVARNPSGDD 249



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 265 PPKIAQKP-RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS----NKHEIITTHN 319
           PP+I  +P R+   + GA  Q      G P+P +TW      L+++      H     H 
Sbjct: 554 PPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHL 613

Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
             TL ++N Q SDSG Y   A+NP G    + Y+ V
Sbjct: 614 QGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 649



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 23/91 (25%), Positives = 40/91 (43%)

Query: 4122 VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGKIE 4181
            ++ G+ A   C VTG PKP++ WLL  N +++ S  + T+       I K +  D+G+  
Sbjct: 180  IKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYV 239

Query: 4182 VIXXXXXXXXXXXXXLKVIPRHDDYRGVLKN 4212
             +             L V+ +     G+  N
Sbjct: 240  CVARNPSGDDTKMYKLDVVSKPPLINGLYTN 270



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 16/125 (12%)

Query: 3113 TKTT--DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ-NIEGLKDGQSAHF 3169
            +KTT  D+G Y C A NK G  E  V LE      GQKP   T+    ++G+  G+S   
Sbjct: 426  SKTTREDAGKYRCAARNKVGYIEKLVILEI-----GQKPVILTYAPGTVKGI-SGESLSL 479

Query: 3170 ECTVVPVDDPDMK---IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             C    +  P++K      Y   +P  +   I  + D G +V+  A    +D G Y+C+A
Sbjct: 480  HCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI--LHDNGTLVIKEATA--YDRGNYICKA 535

Query: 3227 YNKYG 3231
             N  G
Sbjct: 536  QNSVG 540



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 11/128 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI   + +DS  + C A N+ G++ + V+LE ++  +  +P F          + G+S 
Sbjct: 325  LEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR--RPTFRNPFNEKIVAQLGKST 382

Query: 3168 HFECTVVPVDDPDMKIEW-YHNGQPMRH---STRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
               C+V    +P  +I W   NG    +   S +    S+  F+   I+ T   D+G+Y 
Sbjct: 383  ALNCSV--DGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFI---ISKTTREDAGKYR 437

Query: 3224 CRAYNKYG 3231
            C A NK G
Sbjct: 438  CAARNKVG 445



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            T  P  +   K    IK G  A  +   E  GD   ++ WL     + + S I  +    
Sbjct: 165  TAAPRIRQSNKTNKRIKAGDTAVLDC--EVTGDPKPKIFWLLPSNDMISFS-IDRYTFHA 221

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
              +LTI  V + D+G Y C A N  G  T    L +V+K  +I
Sbjct: 222  NGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLI 264



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 3/81 (3%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH---ALMITNVTLSDSGV 462
           G   +  C   G P PE+TW + D  +    + +        H    L+I N   SDSG+
Sbjct: 570 GAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGI 629

Query: 463 VTCVARNKSGETAFQCRLNVI 483
             C A+N  G       + VI
Sbjct: 630 YKCTAKNPLGSDYAATYIQVI 650



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 7/100 (7%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLV----ECNKYSMRYN 123
           +P+    +Q F+  +   G + + + K  G+P P +SW+     ++    + +    R  
Sbjct: 63  KPAKIDHKQYFRK-QVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTR 121

Query: 124 EQT--GDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             T   + +L   ++G  +EG+YTC A+N  G+    V++
Sbjct: 122 RYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHL 161



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSR-YKLTYDGMYHFDIPKTRQY 4175
            + +  + G+     C V G+P P ++W+L NG    NG + Y+        F I KT + 
Sbjct: 372  EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTRE 431

Query: 4176 DTGK 4179
            D GK
Sbjct: 432  DAGK 435



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF-NGKVL---QSGH 1891
            V + + Q P  +T   G  K   G+S    C  +  P PN  ++W   +G V+   Q   
Sbjct: 451  VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPN--IKWTMPSGYVVDRPQING 508

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
            +Y   +D G   +   T Y  D G Y CKA N++G  + ++
Sbjct: 509  KY-ILHDNGTLVIKEATAY--DRGNYICKAQNSVGHTLITV 546



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 9/107 (8%)

Query: 1840 VNQAPRFITQLNGPTK-LSEGQSAHYECRIEPYPDPNMRVEWYF--NGKVLQSGHRYRTS 1896
            +  APR I Q N   K +  G +A  +C +    DP  ++ W    N  +  S  RY T 
Sbjct: 164  ITAAPR-IRQSNKTNKRIKAGDTAVLDCEVTG--DPKPKIFWLLPSNDMISFSIDRY-TF 219

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            +  G  +L I  V   DSGEY C A N  G      +L+V SK  +I
Sbjct: 220  HANG--SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLI 264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 5/101 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTLNDFGFI 3753
            PR     K N  +  G     DC V   GDP  +I W        + S   +T +  G  
Sbjct: 168  PRIRQSNKTNKRIKAGDTAVLDCEV--TGDPKPKIFWLLPSNDMISFSIDRYTFHANG-- 223

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            +L I+ +   D+GEY C A N  G  T   K+   +K  ++
Sbjct: 224  SLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLI 264



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 7/86 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWF--RNEKLIEDSSRITKTHDFGY 2433
            P   Q  +    I+ G TA  DC +   GDP  K+ W    N+ +     R T  H  G 
Sbjct: 168  PRIRQSNKTNKRIKAGDTAVLDCEV--TGDPKPKIFWLLPSNDMISFSIDRYT-FHANG- 223

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             S+TI+ V+  D G Y+C A N  G+
Sbjct: 224  -SLTINKVKLLDSGEYVCVARNPSGD 248



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 6/137 (4%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHL--TIDWFHNGQKIRAGHRYRTTHD 2163
            GQ+PV LT          G+     C  + I  P++  T+   +   + +   +Y   HD
Sbjct: 456  GQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY-ILHD 514

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL 2223
             G + +     Y  D G Y+CKA N +G  + T  + +  +   I + + P  +      
Sbjct: 515  NGTLVIKEATAY--DRGNYICKAQNSVGHTLITVPVMIVAYPPRITN-RPPRSIVTRTGA 571

Query: 2224 EAQGHSTRIEVEEPKIS 2240
              Q H   + V +P+I+
Sbjct: 572  AFQLHCVALGVPKPEIT 588



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 956  SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011
            +R  T FN G   L    V V + G YTC A N +G+     +LT++T    I +S
Sbjct: 120  TRRYTLFNNG--TLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS 173



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 45/161 (27%), Positives = 60/161 (37%), Gaps = 8/161 (4%)

Query: 3075 TGDQSMVIEWFY-NGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            TGD    I W   +   I  S    T +A G   L I   K  DSG Y C A N  G   
Sbjct: 193  TGDPKPKIFWLLPSNDMISFSIDRYTFHANGS--LTINKVKLLDSGEYVCVARNPSGDDT 250

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHN--GQP 3191
               KL+ V K       +T               HF+C       P++      N     
Sbjct: 251  KMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTA 310

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              + +RI TV   G   L+I   +  DS +++C A N+ GE
Sbjct: 311  PYYGSRI-TVHKNG--TLEIRNVRLSDSADFICVARNEGGE 348



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/125 (26%), Positives = 45/125 (36%), Gaps = 6/125 (4%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G Y C+A N  G   I+V +  V       PR T         + G +    C  + V
Sbjct: 527  DRGNYICKAQNSVGHTLITVPVMIV----AYPPRITNRPPRSIVTRTGAAFQLHCVALGV 582

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV--VLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              P++  E   +      S      S+   +   L I   Q  DSG Y C A N  G D+
Sbjct: 583  PKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDY 642

Query: 3235 TRATI 3239
                I
Sbjct: 643  AATYI 647


>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
            adhesion molecule /alternative carboxyl terminus protein.
          Length = 1236

 Score = 88.2 bits (209), Expect = 6e-16
 Identities = 92/386 (23%), Positives = 162/386 (41%), Gaps = 49/386 (12%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P P+I W +E+  +  +    ++    K++ II  V   DS  +  +A+N  G    
Sbjct: 295  EGLPTPIIYWAKEDGMLPKNRT--VYKNFEKTLQIIH-VSEADSGNYQCIAKNALGAIHH 351

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            + ++ V+            P +    QN+ ++ G+   L  +  G     + WL NG  +
Sbjct: 352  TISVRVK----------AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPI 401

Query: 4555 Q--PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
            +  PD  ++ ++ D   T++      + S  Y+C A N  G    +A   V++ A     
Sbjct: 402  EIAPDDPSRKIDGD---TIIFSNVQERSSAVYQCNASNEYGYLLANA--FVNVLAE---- 452

Query: 4613 KPQTKAANAPPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
                     PP I+ P     +++A   A+   C   G PLPT++W+KG K    + +  
Sbjct: 453  ---------PPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAK--GSALHED 500

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +    +  TL I  A  +  G Y CVA N  G       L++  P      P        
Sbjct: 501  IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYA----- 555

Query: 4731 VVYEGQPAQFKTQI--TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            VV  G    F+ ++     +  T+ WL++   +P    F +    +   L++ +  ++D+
Sbjct: 556  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV----DKDHLVVADVSDDDS 611

Query: 4789 GTFTCRATTAAGQVETSAKLVVKSKT 4814
            GT+TC A T    V  SA L V + T
Sbjct: 612  GTYTCVANTTLDSVSASAVLSVVAPT 637



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 77/308 (25%), Positives = 122/308 (39%), Gaps = 34/308 (11%)

Query: 4513 PPSFTL---TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
            PP+F      A N     G ++ L+    G     +YW K    +    +N+ + ++   
Sbjct: 267  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLP---KNRTVYKNFEK 323

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            TL I+     DSG Y+C+A N+ G             A       + KAA   P  I   
Sbjct: 324  TLQIIHVSEADSGNYQCIAKNALG-------------AIHHTISVRVKAA---PYWITAP 367

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
            ++ +++ G+     C+  G P P + W      I+ +     SR  D  T+  S      
Sbjct: 368  QNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAP-DDPSRKIDGDTIIFSNVQERS 426

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV-VYEGQPAQFKTQITSKI 4748
               Y+C A N  G +   A + V     A+    LTP   +  V   +PA          
Sbjct: 427  SAVYQCNASNEYGYLLANAFVNVL----AEPPRILTPANTLYQVIANRPALLDCAFFGSP 482

Query: 4749 KPTIQWLR--EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
             PTI+W +  +G+ + E  D  ++HE  N  L I    ++ TGT+TC A    G  +   
Sbjct: 483  LPTIEWFKGAKGSALHE--DIYVLHE--NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV 538

Query: 4807 KLVVKSKT 4814
             L +K  T
Sbjct: 539  HLEIKDPT 546



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 72/283 (25%), Positives = 115/283 (40%), Gaps = 18/283 (6%)

Query: 291 GNPRPRVTWFKNG-QRLINSNKHEIITTHNHTTLRVRNTQKSDSGH-YTLLAE-NPNGCI 347
           G P P + W  N  QRL  S +   ++   +  L   N    D+   Y   A  N    I
Sbjct: 172 GLPPPIIFWMDNSFQRLPQSER---VSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTI 228

Query: 348 VTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407
                ++V+  +   + D  +  ++DT+    +   E     L P+      +++   G 
Sbjct: 229 QQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE--GNASNKEELRGN 286

Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467
           +   +C   G P P + W   D  +  +      V ++    L I +V+ +DSG   C+A
Sbjct: 287 VLSLECIAEGLPTPIIYWAKEDGMLPKNRT----VYKNFEKTLQIIHVSEADSGNYQCIA 342

Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
           +N  G  A    ++V  K    AP ++     L +  GE   L  RA G P PRI+W  +
Sbjct: 343 KNALG--AIHHTISVRVK---AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTN 397

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           GVPI   P+       G  T+     +   +A YQC A N  G
Sbjct: 398 GVPIEIAPDDPSRKIDG-DTIIFSNVQERSSAVYQCNASNEYG 439



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 53/200 (26%), Positives = 84/200 (42%), Gaps = 16/200 (8%)

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR---DDYNHK 439
           I +  KA AP ++   Q+  ++ G+     CR  G P P ++W  N   I    DD + K
Sbjct: 353 ISVRVKA-APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 411

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           I         ++ +NV    S V  C A N+ G       +NV+ +     P+ +   +T
Sbjct: 412 I-----DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP----PRILTPANT 462

Query: 500 L-NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           L  V    P +L+    G+P P I W K       + ++ +  + G  TL+IP A+    
Sbjct: 463 LYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDST 520

Query: 559 AWYQCTAQNVAGSTATRARL 578
             Y C A+N  G       L
Sbjct: 521 GTYTCVARNKLGMAKNEVHL 540



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 90/424 (21%), Positives = 164/424 (38%), Gaps = 48/424 (11%)

Query: 4409 KPPIFTKKMQPCRVFE-HEQARFEVEFDGEPLPLIKWYRE--NFPIKNSPDFQIHTFS-T 4464
            +PP  T++     + +  E    + E  G+P P   W R   +F I   P   +   + T
Sbjct: 44   QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103

Query: 4465 KSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA-QN 4522
              I I+ +   E    V+   A N  G A  S N+VV   R         P +T    + 
Sbjct: 104  LIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVRPSRS--------PLWTKEKLEP 154

Query: 4523 VNVTSGQLVRLDTKVT-GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            + + SGQ + L  +   G  P  ++W+ N  +  P  +++ + +     L      P+D+
Sbjct: 155  ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLP--QSERVSQGLNGDLYFSNVLPEDT 212

Query: 4582 GK-YECVA----INSAGEARCDAECVVSLPATKDKPKPQTK---------AANAPPEIIE 4627
             + Y C A      +  + +  +  V+S+    D                +   PP  + 
Sbjct: 213  REDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLT 272

Query: 4628 P---LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
            P     +K    G  +   C   G P P + W K D ++  ++    +    E TL+I  
Sbjct: 273  PEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF---EKTLQIIH 329

Query: 4685 AFPEDEGDYKCVAYNSAGRV--TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                D G+Y+C+A N+ G +  T++ ++K            +T  +++V+  G+      
Sbjct: 330  VSEADSGNYQCIAKNALGAIHHTISVRVKAAP-------YWITAPQNLVLSPGEDGTLIC 382

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            +     KP I WL  G  I   PD     + +   ++  N  E  +  + C A+   G +
Sbjct: 383  RANGNPKPRISWLTNGVPIEIAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 441

Query: 4803 ETSA 4806
              +A
Sbjct: 442  LANA 445



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 72/318 (22%), Positives = 130/318 (40%), Gaps = 26/318 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSIL 4468
            P I T      +V  +  A  +  F G PLP I+W++       +   + +H   T  I 
Sbjct: 454  PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIP 513

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            + ++   + +  +  VA N+ G AK   +L +++          P       +   V  G
Sbjct: 514  VAQK---DSTGTYTCVARNKLGMAKNEVHLEIKD----------PTWIVKQPEYAVVQRG 560

Query: 4529 QLVRLDTKV--TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             +V  + KV    T  + V WLK+ +++  D R  + ++D    L++ +    DSG Y C
Sbjct: 561  SMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV-DKD---HLVVADVSDDDSGTYTC 616

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VA N+  ++   A  V+S+ A    P P     N PP  +E L D++    Q        
Sbjct: 617  VA-NTTLDS-VSASAVLSVVAPTPTPAPVYDVPN-PPFDLE-LTDQLDKSVQLSWTPGDD 672

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR--V 4704
               P+        D + KP  +   +  +   T    +  P     ++ +A NS G+   
Sbjct: 673  NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 732

Query: 4705 TVAAKLKVTQPDQADNLP 4722
            + A++  +T+  + D  P
Sbjct: 733  SEASEQYLTKASEPDKNP 750



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 47/180 (26%), Positives = 69/180 (38%), Gaps = 14/180 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP   T    +  +   + A  + +    G     IEWF   K       I  ++  G  
Sbjct: 453  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 508

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LEI   +   +GTY+C A NK G A+  V LE  D      P +         ++ G  
Sbjct: 509  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD------PTWIVKQPEYAVVQRGSM 562

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              FEC V       + + W  + + +    R  TV     VV D++   + DSG Y C A
Sbjct: 563  VSFECKVKHDHTLSLTVLWLKDNRELPSDERF-TVDKDHLVVADVS---DDDSGTYTCVA 618



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 16/197 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RPP F T   +  +  E +        I  G  + +I W      +  +   RTVY    
Sbjct: 266  RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN---RTVYKNFE 322

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              L+I+     DSG Y C A N  G     ISV+++         P + T  QN+  L  
Sbjct: 323  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA-------PYWITAPQNLV-LSP 374

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+     C      +P  +I W  NG P+  +    +    G  ++  +  Q   S  Y 
Sbjct: 375  GEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQ 431

Query: 3224 CRAYNKYGEDFTRATIN 3240
            C A N+YG     A +N
Sbjct: 432  CNASNEYGYLLANAFVN 448



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V + G  + FEC V+     +L + W  +N+ LPS  R+    D   V+ D++   ++DS
Sbjct: 556  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVS---DDDS 611

Query: 2844 GIYTCKATNSKGSATTSGSL 2863
            G YTC A  +  S + S  L
Sbjct: 612  GTYTCVANTTLDSVSASAVL 631



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 265 PPKIAQKPRNSKLQEGAD--AQFQVQLSGNPRPRVTWFKNGQRLINSNKHE-IITTHNHT 321
           PP+I   P N+  Q  A+  A       G+P P + WFK  +    S  HE I   H + 
Sbjct: 453 PPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENG 508

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           TL +   QK  +G YT +A N  G      +L ++ PT
Sbjct: 509 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 546



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP +  A  N+    G +  L CR    G+   R+ W  NG PI+      P+ +
Sbjct: 355  VRVKAAPYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPD-DPSRK 411

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
             D   +   +V    S VY C A+N+ G  + +  + V+A+   IL
Sbjct: 412  IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRIL 457



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 75/331 (22%), Positives = 119/331 (35%), Gaps = 31/331 (9%)

Query: 3042 DDTGRPPEFTTVF-KD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGK--TIEASHRI 3097
            +D  +PP  T    KD I+D  E  +   EA     G       W  NG    I+    +
Sbjct: 40   EDLVQPPTITQQSPKDYIIDPRENIVIQCEAK----GKPPPSFSWTRNGTHFDIDKDPLV 95

Query: 3098 RTVYAFGMVVLEIL--GTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHI 3155
                  G +++ I+  G   T  G Y C A N+ G A   V    V +   + P +T   
Sbjct: 96   TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA---VSNNIVVRPS-RSPLWTKEK 151

Query: 3156 QNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-QPMRHSTRIKTVSDFGFVVLDIAYT 3214
                 L+ GQS    C   P+  P   I W  N  Q +  S R+    +      ++   
Sbjct: 152  LEPITLQSGQSLVLPCRP-PIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 210

Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
               +  +Y+C  Y ++    T           + ++ L     A + + E   GA+    
Sbjct: 211  DTRE--DYIC--YARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE-FYGAKSSRE 265

Query: 3275 STPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR-YRT 3333
                  PP F+T   + +   E +        +    P   + W      LP     Y+ 
Sbjct: 266  -----RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKN 320

Query: 3334 FHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            F       L I++  E +SG Y+C+A N LG
Sbjct: 321  FEK----TLQIIHVSEADSGNYQCIAKNALG 347



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            + +  P +++ P  + +  GE     CR  G+PKPR+ WL NG
Sbjct: 356  RVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 398



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 7/117 (5%)

Query: 1167 YQIEEISKSKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            Y  +   +  P F+ P  N     E  G  + LEC  E  G PT  + W      +    
Sbjct: 258  YGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE--GLPTPIIYWAKEDGMLP--- 312

Query: 1225 RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281
            + +T Y      L IIH + AD+G Y   A N LG+ H +  VRV      +T  QN
Sbjct: 313  KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN 369



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980
            ++ G    FE +++     +L V WLKD R + +  R T   +     L +  V+  D+G
Sbjct: 557  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 612

Query: 981  HYTCRAYNAIGQATTSANLTIV 1002
             YTC A   +   + SA L++V
Sbjct: 613  TYTCVANTTLDSVSASAVLSVV 634



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            AEPP+ +T    + +++  + A  +        P   +EWF   K           H+ G
Sbjct: 451  AEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG 508

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
               L+I    ++++G Y CVA NKLG    + +L+
Sbjct: 509  T--LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 541



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            +  G    FE +V+    L++TV W  + +++ S  R     D     L +A V  +DSG
Sbjct: 557  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 612

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
             YT VA         SA ++V
Sbjct: 613  TYTCVANTTLDSVSASAVLSV 633



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 272 PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
           P+N  L  G D     + +GNP+PR++W  NG   I     +     +  T+   N Q+ 
Sbjct: 367 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVP-IEIAPDDPSRKIDGDTIIFSNVQER 425

Query: 332 DSGHYTLLAENPNGCIVTSGYLAV 355
            S  Y   A N  G ++ + ++ V
Sbjct: 426 SSAVYQCNASNEYGYLLANAFVNV 449



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/159 (25%), Positives = 67/159 (42%), Gaps = 12/159 (7%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP   T  + L  +  N  A  +C           +EWF   K       +  +++ G  
Sbjct: 453  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 508

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ-- 3673
             LEI    +   G YTC A N+ G A     L++K    I+ +P+     +    S +  
Sbjct: 509  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 568

Query: 3674 -KLEETLHKREEITIED--EKPNPPRFTVEIKDNIDVPE 3709
             K + TL     + ++D  E P+  RFTV+ KD++ V +
Sbjct: 569  VKHDHTL-SLTVLWLKDNRELPSDERFTVD-KDHLVVAD 605



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 4/86 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PPR          V    P   DC     G P   I+WF   +  A    ++ L++ G  
Sbjct: 453  PPRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWFKGAKGSALHEDIYVLHENG-- 508

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSA 3779
             L+I        G YTC A NK G A
Sbjct: 509  TLEIPVAQKDSTGTYTCVARNKLGMA 534



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 8/90 (8%)

Query: 2372 TRQRP-VFTQPLQNIDNIQE--GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428
            +R+RP  F  P  N  N +E  G     +C  I  G PT  + W + + ++  +  + K 
Sbjct: 263  SRERPPTFLTPEGNASNKEELRGNVLSLEC--IAEGLPTPIIYWAKEDGMLPKNRTVYKN 320

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             +    ++ I HV + D G Y C A N LG
Sbjct: 321  FE---KTLQIIHVSEADSGNYQCIAKNALG 347



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 3/102 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P + T P +L+LS        CR     +   R+ W  NG P+       +    G  I+
Sbjct: 361  PYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 418

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
                V +R + +Y C A+N +G    +  + V      IL P
Sbjct: 419  -FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 459



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 43/170 (25%), Positives = 63/170 (37%), Gaps = 16/170 (9%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           DC   G P P + WF   +  +    H+ +     N  L I       +G  TCVARNK 
Sbjct: 475 DCAFFGSPLPTIEWF---KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 531

Query: 472 GETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTPRIT--WQKDG 528
           G    +  L + +   +V  P++        V+ G  V    +     T  +T  W KD 
Sbjct: 532 GMAKNEVHLEIKDPTWIVKQPEYAV------VQRGSMVSFECKVKHDHTLSLTVLWLKDN 585

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +P+ E R   D     L +      D+  Y C A     S +  A L
Sbjct: 586 RE-LPSDE-RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVL 631



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P ++ +      V  G  V FECK++     +L V W K+ + +    RF    D   VA
Sbjct: 545  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA 604

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540
             D+ D   +DSG YTC A   + +   S  L+  + T
Sbjct: 605  -DVSD---DDSGTYTCVANTTLDSVSASAVLSVVAPT 637



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            IEWFK          +    + G  TL I   + D +G YTC A N LG A +   ++I+
Sbjct: 486  IEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 543

Query: 2736 DRHWLL 2741
            D  W++
Sbjct: 544  DPTWIV 549



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           P I +Q  K+       N   + + +G P P  SWTR            +     TG + 
Sbjct: 46  PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 105

Query: 131 LLIKQIGPGD--EGEYTCTARNQYGEAIC-SVYIQP 163
           + I   G  +  EG Y CTARN+ G A+  ++ ++P
Sbjct: 106 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRP 141



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 8/100 (8%)

Query: 3829 PPKFIT-QIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            PP F+T +  +   EE  G  +  EC  E    P   I W +   +LP     RTVY   
Sbjct: 267  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPI--IYWAKEDGMLPKN---RTVYKNF 321

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              +L I++V   DSG Y C A N  G      ++  K  P
Sbjct: 322  EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 361



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G+PK R+ WL NGVPIE +    +    G   +    V    S  Y C A NE G
Sbjct: 386  GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYG 439



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + PR +T  N   ++   + A  +C     P P   +EW+   K           ++ G 
Sbjct: 452  EPPRILTPANTLYQVIANRPALLDCAFFGSPLPT--IEWFKGAKGSALHEDIYVLHENG- 508

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
              L+I     + +G YTC A N LG A + + L ++    I++  ++
Sbjct: 509  -TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEY 554



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-YRTTHDFGYV 2167
            P  LT   +L  +     A  +C       P  TI+WF  G K  A H      H+ G  
Sbjct: 454  PRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWF-KGAKGSALHEDIYVLHENG-- 508

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L+I     + +GTY C A NKLG A N   L++
Sbjct: 509  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI 542



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 3813 RGRISDAPKEEPI-VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            R ++  A  E  + +  P   + Q +   V+    V FEC+V+      L + W ++ + 
Sbjct: 528  RNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRE 587

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906
            LPS  R+    D     L +  V  +DSG Y C A
Sbjct: 588  LPSDERFTVDKD----HLVVADVSDDDSGTYTCVA 618



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P ++        ++ G    FEC+V+  +   LT+ W  + +++ +  R+    D   VA
Sbjct: 545  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA 604

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             D+     +DSGTY C A   L     +  L V
Sbjct: 605  -DV---SDDDSGTYTCVANTTLDSVSASAVLSV 633



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1589 IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSG 1648
            ++ G    FE ++      +L V W  +N+ L S  RFT   +   V  D+     +DSG
Sbjct: 557  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSD---DDSG 612

Query: 1649 TYTCRAINALGEAVTSGIAIV 1669
            TYTC A   L     S +  V
Sbjct: 613  TYTCVANTTLDSVSASAVLSV 633



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 7/110 (6%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVE-GQVLHLEGQVEPKNDPDLKIEWYFNG 2951
            AR   G   +    E   P WI+    E+ +V+ G ++  E +V+  +   L + W  + 
Sbjct: 527  ARNKLGMAKNEVHLEIKDPTWIVK-QPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDN 585

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + L    RF +  D     L + DV + DSG YTC A N   ++ ++S V
Sbjct: 586  RELPSDERFTVDKDH----LVVADVSDDDSGTYTCVA-NTTLDSVSASAV 630



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G+ V  EC+++     ++ V W  + + + +  RF      D   L +  V  +DSG YT
Sbjct: 560  GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 615

Query: 1385 CQATNQLGEAVTSCALRVIA 1404
            C A   L     S  L V+A
Sbjct: 616  CVANTTLDSVSASAVLSVVA 635



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 52/224 (23%), Positives = 87/224 (38%), Gaps = 18/224 (8%)

Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG-QSIEASSRFTSIFRFGYISLDMLSL 701
           L+ +T   G  +    R  P+G P   I W+ N  Q +  S R +          ++L  
Sbjct: 152 LEPITLQSGQSLVLPCR-PPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 210

Query: 702 NIQDSGEYTCRA-VSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQE 760
           + ++  +Y C A  + T   + K  + V   +  E      +T+     L D   Y  + 
Sbjct: 211 DTRE--DYICYARFNHTQTIQQKQPISVKVISVDELN----DTIA--ANLSDTEFYGAKS 262

Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           S E      P F+ P  +    +E R      +      PT  + W K+   +  +  + 
Sbjct: 263 SRERP----PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 318

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
             F     +L I+H+   D+G+Y   A N LG    T S+RV A
Sbjct: 319 KNFE---KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 359



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P +I +      +  G    +EC+++     ++ V W  + + L S  R+    D     
Sbjct: 545  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH---- 600

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            L +  V  +DSG YTC A   L    +S  L+V
Sbjct: 601  LVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + PR L P     +++  + A  +      S L  T+EW+   K       I   H+ 
Sbjct: 450  LAEPPRILTPANTLYQVIANRPALLDCAFFG-SPLP-TIEWFKGAKGSALHEDIYVLHEN 507

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            G   L+I   + + +G YT VARN  G A+    + ++
Sbjct: 508  G--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 543



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 9/120 (7%)

Query: 637 PQFIVPLKSVTAME-GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           P +IV       ++ G  + FE +++     ++ + WLK+ + + +  RFT         
Sbjct: 545 PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDH 600

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV---TPR-ATIERTSQHPETLQYIQQLE 751
           L +  ++  DSG YTC A +        AVL V   TP  A +      P  L+   QL+
Sbjct: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 660



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 4/91 (4%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P +I +  +   +  G    FE ++       L V W  + ++LP   R+    D  +V+
Sbjct: 545  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVV 603

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             D+    +++SG Y CVA   L   S  A L
Sbjct: 604  ADV---SDDDSGTYTCVANTTLDSVSASAVL 631



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q G    F+C++      +L V W ++ + +    R T   D     + ++ V D+D G
Sbjct: 557  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVADVSDDDSG 612

Query: 2448 VYMCRASNLL 2457
             Y C A+  L
Sbjct: 613  TYTCVANTTL 622



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 6/97 (6%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT--WFKNGQRLINSNKHEIITTHNHTT 322
           P  I ++P  + +Q G+   F+ ++  +    +T  W K+ + L +  +  +   H    
Sbjct: 545 PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH---- 600

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           L V +    DSG YT +A      +  S  L+V +PT
Sbjct: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPT 637



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 4/97 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            E  +P      P   ++   S   FEC++   +  S+ V W  + + L +  R     D 
Sbjct: 541  EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 600

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                L +  V   D+G YTC A       + S  L V
Sbjct: 601  ----LVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 3/67 (4%)

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           G  + L   A G PTP I W K+   +   P+ R        TL I     +D+  YQC 
Sbjct: 285 GNVLSLECIAEGLPTPIIYWAKEDGML---PKNRTVYKNFEKTLQIIHVSEADSGNYQCI 341

Query: 565 AQNVAGS 571
           A+N  G+
Sbjct: 342 AKNALGA 348



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%)

Query: 1706 VITQAPVFTMPMKDI-RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            V+ + P    P   + +V  N+ A  +      G P   +EW +          +  +H+
Sbjct: 449  VLAEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHE 506

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
             G   L +     + +GTYTC A N+LG A
Sbjct: 507  NG--TLEIPVAQKDSTGTYTCVARNKLGMA 534



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 7/93 (7%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVT--WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
           V  G M  F+C+V       +T  W  ++R++  D   +  V++  +H L++ +V+  DS
Sbjct: 557 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSD--ERFTVDK--DH-LVVADVSDDDS 611

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
           G  TCVA       +    L+V+      AP +
Sbjct: 612 GTYTCVANTTLDSVSASAVLSVVAPTPTPAPVY 644


>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
            adhesion molecule protein.
          Length = 1308

 Score = 88.2 bits (209), Expect = 6e-16
 Identities = 92/386 (23%), Positives = 162/386 (41%), Gaps = 49/386 (12%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P P+I W +E+  +  +    ++    K++ II  V   DS  +  +A+N  G    
Sbjct: 295  EGLPTPIIYWAKEDGMLPKNRT--VYKNFEKTLQIIH-VSEADSGNYQCIAKNALGAIHH 351

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            + ++ V+            P +    QN+ ++ G+   L  +  G     + WL NG  +
Sbjct: 352  TISVRVK----------AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPI 401

Query: 4555 Q--PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
            +  PD  ++ ++ D   T++      + S  Y+C A N  G    +A   V++ A     
Sbjct: 402  EIAPDDPSRKIDGD---TIIFSNVQERSSAVYQCNASNEYGYLLANA--FVNVLAE---- 452

Query: 4613 KPQTKAANAPPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
                     PP I+ P     +++A   A+   C   G PLPT++W+KG K    + +  
Sbjct: 453  ---------PPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAK--GSALHED 500

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +    +  TL I  A  +  G Y CVA N  G       L++  P      P        
Sbjct: 501  IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYA----- 555

Query: 4731 VVYEGQPAQFKTQI--TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            VV  G    F+ ++     +  T+ WL++   +P    F +    +   L++ +  ++D+
Sbjct: 556  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV----DKDHLVVADVSDDDS 611

Query: 4789 GTFTCRATTAAGQVETSAKLVVKSKT 4814
            GT+TC A T    V  SA L V + T
Sbjct: 612  GTYTCVANTTLDSVSASAVLSVVAPT 637



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 77/308 (25%), Positives = 122/308 (39%), Gaps = 34/308 (11%)

Query: 4513 PPSFTL---TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
            PP+F      A N     G ++ L+    G     +YW K    +    +N+ + ++   
Sbjct: 267  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLP---KNRTVYKNFEK 323

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            TL I+     DSG Y+C+A N+ G             A       + KAA   P  I   
Sbjct: 324  TLQIIHVSEADSGNYQCIAKNALG-------------AIHHTISVRVKAA---PYWITAP 367

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
            ++ +++ G+     C+  G P P + W      I+ +     SR  D  T+  S      
Sbjct: 368  QNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAP-DDPSRKIDGDTIIFSNVQERS 426

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV-VYEGQPAQFKTQITSKI 4748
               Y+C A N  G +   A + V     A+    LTP   +  V   +PA          
Sbjct: 427  SAVYQCNASNEYGYLLANAFVNVL----AEPPRILTPANTLYQVIANRPALLDCAFFGSP 482

Query: 4749 KPTIQWLR--EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
             PTI+W +  +G+ + E  D  ++HE  N  L I    ++ TGT+TC A    G  +   
Sbjct: 483  LPTIEWFKGAKGSALHE--DIYVLHE--NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV 538

Query: 4807 KLVVKSKT 4814
             L +K  T
Sbjct: 539  HLEIKDPT 546



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 72/283 (25%), Positives = 115/283 (40%), Gaps = 18/283 (6%)

Query: 291 GNPRPRVTWFKNG-QRLINSNKHEIITTHNHTTLRVRNTQKSDSGH-YTLLAE-NPNGCI 347
           G P P + W  N  QRL  S +   ++   +  L   N    D+   Y   A  N    I
Sbjct: 172 GLPPPIIFWMDNSFQRLPQSER---VSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTI 228

Query: 348 VTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407
                ++V+  +   + D  +  ++DT+    +   E     L P+      +++   G 
Sbjct: 229 QQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE--GNASNKEELRGN 286

Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467
           +   +C   G P P + W   D  +  +      V ++    L I +V+ +DSG   C+A
Sbjct: 287 VLSLECIAEGLPTPIIYWAKEDGMLPKNRT----VYKNFEKTLQIIHVSEADSGNYQCIA 342

Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
           +N  G  A    ++V  K    AP ++     L +  GE   L  RA G P PRI+W  +
Sbjct: 343 KNALG--AIHHTISVRVK---AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTN 397

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           GVPI   P+       G  T+     +   +A YQC A N  G
Sbjct: 398 GVPIEIAPDDPSRKIDG-DTIIFSNVQERSSAVYQCNASNEYG 439



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 53/200 (26%), Positives = 84/200 (42%), Gaps = 16/200 (8%)

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR---DDYNHK 439
           I +  KA AP ++   Q+  ++ G+     CR  G P P ++W  N   I    DD + K
Sbjct: 353 ISVRVKA-APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 411

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           I         ++ +NV    S V  C A N+ G       +NV+ +     P+ +   +T
Sbjct: 412 I-----DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP----PRILTPANT 462

Query: 500 L-NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           L  V    P +L+    G+P P I W K       + ++ +  + G  TL+IP A+    
Sbjct: 463 LYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDST 520

Query: 559 AWYQCTAQNVAGSTATRARL 578
             Y C A+N  G       L
Sbjct: 521 GTYTCVARNKLGMAKNEVHL 540



 Score = 62.9 bits (146), Expect = 3e-08
 Identities = 90/424 (21%), Positives = 164/424 (38%), Gaps = 48/424 (11%)

Query: 4409 KPPIFTKKMQPCRVFE-HEQARFEVEFDGEPLPLIKWYRE--NFPIKNSPDFQIHTFS-T 4464
            +PP  T++     + +  E    + E  G+P P   W R   +F I   P   +   + T
Sbjct: 44   QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103

Query: 4465 KSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA-QN 4522
              I I+ +   E    V+   A N  G A  S N+VV   R         P +T    + 
Sbjct: 104  LIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVRPSRS--------PLWTKEKLEP 154

Query: 4523 VNVTSGQLVRLDTKVT-GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            + + SGQ + L  +   G  P  ++W+ N  +  P  +++ + +     L      P+D+
Sbjct: 155  ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLP--QSERVSQGLNGDLYFSNVLPEDT 212

Query: 4582 GK-YECVA----INSAGEARCDAECVVSLPATKDKPKPQTK---------AANAPPEIIE 4627
             + Y C A      +  + +  +  V+S+    D                +   PP  + 
Sbjct: 213  REDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLT 272

Query: 4628 P---LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
            P     +K    G  +   C   G P P + W K D ++  ++    +    E TL+I  
Sbjct: 273  PEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF---EKTLQIIH 329

Query: 4685 AFPEDEGDYKCVAYNSAGRV--TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                D G+Y+C+A N+ G +  T++ ++K            +T  +++V+  G+      
Sbjct: 330  VSEADSGNYQCIAKNALGAIHHTISVRVKAAP-------YWITAPQNLVLSPGEDGTLIC 382

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            +     KP I WL  G  I   PD     + +   ++  N  E  +  + C A+   G +
Sbjct: 383  RANGNPKPRISWLTNGVPIEIAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 441

Query: 4803 ETSA 4806
              +A
Sbjct: 442  LANA 445



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 72/318 (22%), Positives = 130/318 (40%), Gaps = 26/318 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSIL 4468
            P I T      +V  +  A  +  F G PLP I+W++       +   + +H   T  I 
Sbjct: 454  PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIP 513

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            + ++   + +  +  VA N+ G AK   +L +++          P       +   V  G
Sbjct: 514  VAQK---DSTGTYTCVARNKLGMAKNEVHLEIKD----------PTWIVKQPEYAVVQRG 560

Query: 4529 QLVRLDTKV--TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             +V  + KV    T  + V WLK+ +++  D R  + ++D    L++ +    DSG Y C
Sbjct: 561  SMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV-DKD---HLVVADVSDDDSGTYTC 616

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VA N+  ++   A  V+S+ A    P P     N PP  +E L D++    Q        
Sbjct: 617  VA-NTTLDS-VSASAVLSVVAPTPTPAPVYDVPN-PPFDLE-LTDQLDKSVQLSWTPGDD 672

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR--V 4704
               P+        D + KP  +   +  +   T    +  P     ++ +A NS G+   
Sbjct: 673  NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 732

Query: 4705 TVAAKLKVTQPDQADNLP 4722
            + A++  +T+  + D  P
Sbjct: 733  SEASEQYLTKASEPDKNP 750



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 47/180 (26%), Positives = 69/180 (38%), Gaps = 14/180 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP   T    +  +   + A  + +    G     IEWF   K       I  ++  G  
Sbjct: 453  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 508

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LEI   +   +GTY+C A NK G A+  V LE  D      P +         ++ G  
Sbjct: 509  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD------PTWIVKQPEYAVVQRGSM 562

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              FEC V       + + W  + + +    R  TV     VV D++   + DSG Y C A
Sbjct: 563  VSFECKVKHDHTLSLTVLWLKDNRELPSDERF-TVDKDHLVVADVS---DDDSGTYTCVA 618



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 16/197 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RPP F T   +  +  E +        I  G  + +I W      +  +   RTVY    
Sbjct: 266  RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN---RTVYKNFE 322

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              L+I+     DSG Y C A N  G     ISV+++         P + T  QN+  L  
Sbjct: 323  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA-------PYWITAPQNLV-LSP 374

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+     C      +P  +I W  NG P+  +    +    G  ++  +  Q   S  Y 
Sbjct: 375  GEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQ 431

Query: 3224 CRAYNKYGEDFTRATIN 3240
            C A N+YG     A +N
Sbjct: 432  CNASNEYGYLLANAFVN 448



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V + G  + FEC V+     +L + W  +N+ LPS  R+    D   V+ D++   ++DS
Sbjct: 556  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVS---DDDS 611

Query: 2844 GIYTCKATNSKGSATTSGSL 2863
            G YTC A  +  S + S  L
Sbjct: 612  GTYTCVANTTLDSVSASAVL 631



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 265 PPKIAQKPRNSKLQEGAD--AQFQVQLSGNPRPRVTWFKNGQRLINSNKHE-IITTHNHT 321
           PP+I   P N+  Q  A+  A       G+P P + WFK  +    S  HE I   H + 
Sbjct: 453 PPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENG 508

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           TL +   QK  +G YT +A N  G      +L ++ PT
Sbjct: 509 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 546



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP +  A  N+    G +  L CR    G+   R+ W  NG PI+      P+ +
Sbjct: 355  VRVKAAPYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPD-DPSRK 411

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
             D   +   +V    S VY C A+N+ G  + +  + V+A+   IL
Sbjct: 412  IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRIL 457



 Score = 44.0 bits (99), Expect = 0.014
 Identities = 75/331 (22%), Positives = 119/331 (35%), Gaps = 31/331 (9%)

Query: 3042 DDTGRPPEFTTVF-KD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGK--TIEASHRI 3097
            +D  +PP  T    KD I+D  E  +   EA     G       W  NG    I+    +
Sbjct: 40   EDLVQPPTITQQSPKDYIIDPRENIVIQCEAK----GKPPPSFSWTRNGTHFDIDKDPLV 95

Query: 3098 RTVYAFGMVVLEIL--GTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHI 3155
                  G +++ I+  G   T  G Y C A N+ G A   V    V +   + P +T   
Sbjct: 96   TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA---VSNNIVVRPS-RSPLWTKEK 151

Query: 3156 QNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-QPMRHSTRIKTVSDFGFVVLDIAYT 3214
                 L+ GQS    C   P+  P   I W  N  Q +  S R+    +      ++   
Sbjct: 152  LEPITLQSGQSLVLPCRP-PIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 210

Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
               +  +Y+C  Y ++    T           + ++ L     A + + E   GA+    
Sbjct: 211  DTRE--DYIC--YARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE-FYGAKSSRE 265

Query: 3275 STPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR-YRT 3333
                  PP F+T   + +   E +        +    P   + W      LP     Y+ 
Sbjct: 266  -----RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKN 320

Query: 3334 FHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            F       L I++  E +SG Y+C+A N LG
Sbjct: 321  FEK----TLQIIHVSEADSGNYQCIAKNALG 347



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            + +  P +++ P  + +  GE     CR  G+PKPR+ WL NG
Sbjct: 356  RVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 398



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 7/117 (5%)

Query: 1167 YQIEEISKSKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            Y  +   +  P F+ P  N     E  G  + LEC  E  G PT  + W      +    
Sbjct: 258  YGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE--GLPTPIIYWAKEDGMLP--- 312

Query: 1225 RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281
            + +T Y      L IIH + AD+G Y   A N LG+ H +  VRV      +T  QN
Sbjct: 313  KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN 369



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980
            ++ G    FE +++     +L V WLKD R + +  R T   +     L +  V+  D+G
Sbjct: 557  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 612

Query: 981  HYTCRAYNAIGQATTSANLTIV 1002
             YTC A   +   + SA L++V
Sbjct: 613  TYTCVANTTLDSVSASAVLSVV 634



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            AEPP+ +T    + +++  + A  +        P   +EWF   K           H+ G
Sbjct: 451  AEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG 508

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
               L+I    ++++G Y CVA NKLG    + +L+
Sbjct: 509  T--LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 541



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            +  G    FE +V+    L++TV W  + +++ S  R     D     L +A V  +DSG
Sbjct: 557  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 612

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
             YT VA         SA ++V
Sbjct: 613  TYTCVANTTLDSVSASAVLSV 633



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 272 PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
           P+N  L  G D     + +GNP+PR++W  NG   I     +     +  T+   N Q+ 
Sbjct: 367 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVP-IEIAPDDPSRKIDGDTIIFSNVQER 425

Query: 332 DSGHYTLLAENPNGCIVTSGYLAV 355
            S  Y   A N  G ++ + ++ V
Sbjct: 426 SSAVYQCNASNEYGYLLANAFVNV 449



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/159 (25%), Positives = 67/159 (42%), Gaps = 12/159 (7%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP   T  + L  +  N  A  +C           +EWF   K       +  +++ G  
Sbjct: 453  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 508

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ-- 3673
             LEI    +   G YTC A N+ G A     L++K    I+ +P+     +    S +  
Sbjct: 509  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 568

Query: 3674 -KLEETLHKREEITIED--EKPNPPRFTVEIKDNIDVPE 3709
             K + TL     + ++D  E P+  RFTV+ KD++ V +
Sbjct: 569  VKHDHTL-SLTVLWLKDNRELPSDERFTVD-KDHLVVAD 605



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 4/86 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PPR          V    P   DC     G P   I+WF   +  A    ++ L++ G  
Sbjct: 453  PPRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWFKGAKGSALHEDIYVLHENG-- 508

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSA 3779
             L+I        G YTC A NK G A
Sbjct: 509  TLEIPVAQKDSTGTYTCVARNKLGMA 534



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 8/90 (8%)

Query: 2372 TRQRP-VFTQPLQNIDNIQE--GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428
            +R+RP  F  P  N  N +E  G     +C  I  G PT  + W + + ++  +  + K 
Sbjct: 263  SRERPPTFLTPEGNASNKEELRGNVLSLEC--IAEGLPTPIIYWAKEDGMLPKNRTVYKN 320

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             +    ++ I HV + D G Y C A N LG
Sbjct: 321  FE---KTLQIIHVSEADSGNYQCIAKNALG 347



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 3/102 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P + T P +L+LS        CR     +   R+ W  NG P+       +    G  I+
Sbjct: 361  PYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 418

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
                V +R + +Y C A+N +G    +  + V      IL P
Sbjct: 419  -FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 459



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 43/170 (25%), Positives = 63/170 (37%), Gaps = 16/170 (9%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           DC   G P P + WF   +  +    H+ +     N  L I       +G  TCVARNK 
Sbjct: 475 DCAFFGSPLPTIEWF---KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 531

Query: 472 GETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTPRIT--WQKDG 528
           G    +  L + +   +V  P++        V+ G  V    +     T  +T  W KD 
Sbjct: 532 GMAKNEVHLEIKDPTWIVKQPEYAV------VQRGSMVSFECKVKHDHTLSLTVLWLKDN 585

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +P+ E R   D     L +      D+  Y C A     S +  A L
Sbjct: 586 RE-LPSDE-RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVL 631



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P ++ +      V  G  V FECK++     +L V W K+ + +    RF    D   VA
Sbjct: 545  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA 604

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540
             D+ D   +DSG YTC A   + +   S  L+  + T
Sbjct: 605  -DVSD---DDSGTYTCVANTTLDSVSASAVLSVVAPT 637



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            IEWFK          +    + G  TL I   + D +G YTC A N LG A +   ++I+
Sbjct: 486  IEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 543

Query: 2736 DRHWLL 2741
            D  W++
Sbjct: 544  DPTWIV 549



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           P I +Q  K+       N   + + +G P P  SWTR            +     TG + 
Sbjct: 46  PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 105

Query: 131 LLIKQIGPGD--EGEYTCTARNQYGEAIC-SVYIQP 163
           + I   G  +  EG Y CTARN+ G A+  ++ ++P
Sbjct: 106 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRP 141



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 8/100 (8%)

Query: 3829 PPKFIT-QIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            PP F+T +  +   EE  G  +  EC  E    P   I W +   +LP     RTVY   
Sbjct: 267  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPI--IYWAKEDGMLPKN---RTVYKNF 321

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              +L I++V   DSG Y C A N  G      ++  K  P
Sbjct: 322  EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 361



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G+PK R+ WL NGVPIE +    +    G   +    V    S  Y C A NE G
Sbjct: 386  GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYG 439



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + PR +T  N   ++   + A  +C     P P   +EW+   K           ++ G 
Sbjct: 452  EPPRILTPANTLYQVIANRPALLDCAFFGSPLPT--IEWFKGAKGSALHEDIYVLHENG- 508

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
              L+I     + +G YTC A N LG A + + L ++    I++  ++
Sbjct: 509  -TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEY 554



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-YRTTHDFGYV 2167
            P  LT   +L  +     A  +C       P  TI+WF  G K  A H      H+ G  
Sbjct: 454  PRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWF-KGAKGSALHEDIYVLHENG-- 508

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L+I     + +GTY C A NKLG A N   L++
Sbjct: 509  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI 542



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 3813 RGRISDAPKEEPI-VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            R ++  A  E  + +  P   + Q +   V+    V FEC+V+      L + W ++ + 
Sbjct: 528  RNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRE 587

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906
            LPS  R+    D     L +  V  +DSG Y C A
Sbjct: 588  LPSDERFTVDKD----HLVVADVSDDDSGTYTCVA 618



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P ++        ++ G    FEC+V+  +   LT+ W  + +++ +  R+    D   VA
Sbjct: 545  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA 604

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             D+     +DSGTY C A   L     +  L V
Sbjct: 605  -DV---SDDDSGTYTCVANTTLDSVSASAVLSV 633



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1589 IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSG 1648
            ++ G    FE ++      +L V W  +N+ L S  RFT   +   V  D+     +DSG
Sbjct: 557  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSD---DDSG 612

Query: 1649 TYTCRAINALGEAVTSGIAIV 1669
            TYTC A   L     S +  V
Sbjct: 613  TYTCVANTTLDSVSASAVLSV 633



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 7/110 (6%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVE-GQVLHLEGQVEPKNDPDLKIEWYFNG 2951
            AR   G   +    E   P WI+    E+ +V+ G ++  E +V+  +   L + W  + 
Sbjct: 527  ARNKLGMAKNEVHLEIKDPTWIVK-QPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDN 585

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + L    RF +  D     L + DV + DSG YTC A N   ++ ++S V
Sbjct: 586  RELPSDERFTVDKDH----LVVADVSDDDSGTYTCVA-NTTLDSVSASAV 630



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G+ V  EC+++     ++ V W  + + + +  RF      D   L +  V  +DSG YT
Sbjct: 560  GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 615

Query: 1385 CQATNQLGEAVTSCALRVIA 1404
            C A   L     S  L V+A
Sbjct: 616  CVANTTLDSVSASAVLSVVA 635



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 52/224 (23%), Positives = 87/224 (38%), Gaps = 18/224 (8%)

Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG-QSIEASSRFTSIFRFGYISLDMLSL 701
           L+ +T   G  +    R  P+G P   I W+ N  Q +  S R +          ++L  
Sbjct: 152 LEPITLQSGQSLVLPCR-PPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 210

Query: 702 NIQDSGEYTCRA-VSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQE 760
           + ++  +Y C A  + T   + K  + V   +  E      +T+     L D   Y  + 
Sbjct: 211 DTRE--DYICYARFNHTQTIQQKQPISVKVISVDELN----DTIA--ANLSDTEFYGAKS 262

Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           S E      P F+ P  +    +E R      +      PT  + W K+   +  +  + 
Sbjct: 263 SRERP----PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 318

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
             F     +L I+H+   D+G+Y   A N LG    T S+RV A
Sbjct: 319 KNFE---KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 359



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P +I +      +  G    +EC+++     ++ V W  + + L S  R+    D     
Sbjct: 545  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH---- 600

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            L +  V  +DSG YTC A   L    +S  L+V
Sbjct: 601  LVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + PR L P     +++  + A  +      S L  T+EW+   K       I   H+ 
Sbjct: 450  LAEPPRILTPANTLYQVIANRPALLDCAFFG-SPLP-TIEWFKGAKGSALHEDIYVLHEN 507

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            G   L+I   + + +G YT VARN  G A+    + ++
Sbjct: 508  G--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 543



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 9/120 (7%)

Query: 637 PQFIVPLKSVTAME-GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           P +IV       ++ G  + FE +++     ++ + WLK+ + + +  RFT         
Sbjct: 545 PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDH 600

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV---TPR-ATIERTSQHPETLQYIQQLE 751
           L +  ++  DSG YTC A +        AVL V   TP  A +      P  L+   QL+
Sbjct: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 660



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 4/91 (4%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P +I +  +   +  G    FE ++       L V W  + ++LP   R+    D  +V+
Sbjct: 545  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVV 603

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             D+    +++SG Y CVA   L   S  A L
Sbjct: 604  ADV---SDDDSGTYTCVANTTLDSVSASAVL 631



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q G    F+C++      +L V W ++ + +    R T   D     + ++ V D+D G
Sbjct: 557  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVADVSDDDSG 612

Query: 2448 VYMCRASNLL 2457
             Y C A+  L
Sbjct: 613  TYTCVANTTL 622



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 6/97 (6%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT--WFKNGQRLINSNKHEIITTHNHTT 322
           P  I ++P  + +Q G+   F+ ++  +    +T  W K+ + L +  +  +   H    
Sbjct: 545 PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH---- 600

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           L V +    DSG YT +A      +  S  L+V +PT
Sbjct: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPT 637



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 4/97 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            E  +P      P   ++   S   FEC++   +  S+ V W  + + L +  R     D 
Sbjct: 541  EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 600

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                L +  V   D+G YTC A       + S  L V
Sbjct: 601  ----LVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 3/67 (4%)

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           G  + L   A G PTP I W K+   +   P+ R        TL I     +D+  YQC 
Sbjct: 285 GNVLSLECIAEGLPTPIIYWAKEDGML---PKNRTVYKNFEKTLQIIHVSEADSGNYQCI 341

Query: 565 AQNVAGS 571
           A+N  G+
Sbjct: 342 AKNALGA 348



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%)

Query: 1706 VITQAPVFTMPMKDI-RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            V+ + P    P   + +V  N+ A  +      G P   +EW +          +  +H+
Sbjct: 449  VLAEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHE 506

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
             G   L +     + +GTYTC A N+LG A
Sbjct: 507  NG--TLEIPVAQKDSTGTYTCVARNKLGMA 534



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 7/93 (7%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVT--WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
           V  G M  F+C+V       +T  W  ++R++  D   +  V++  +H L++ +V+  DS
Sbjct: 557 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSD--ERFTVDK--DH-LVVADVSDDDS 611

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
           G  TCVA       +    L+V+      AP +
Sbjct: 612 GTYTCVANTTLDSVSASAVLSVVAPTPTPAPVY 644


>AB040929-1|BAA96020.1|  920|Homo sapiens KIAA1496 protein protein.
          Length = 920

 Score = 87.8 bits (208), Expect = 8e-16
 Identities = 91/380 (23%), Positives = 148/380 (38%), Gaps = 41/380 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P I W R +  +  S   ++  FS   +L I     ED+  +  +AEN  G     
Sbjct: 145  GNPIPQINWRRSD-GLPFSSKIKLRKFS--GVLEIPNFQQEDAGSYECIAENSRGKNVAR 201

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              L    K          P +    ++V +     +  + + +G       WLKNG  + 
Sbjct: 202  GRLTYYAK----------PHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALV 251

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
             + R +I  E+G  T+  L     DSG ++C+A N  G     AE  V            
Sbjct: 252  LEERTQI--ENGALTISNLSV--TDSGMFQCIAENKHGLVYSSAELKV------------ 295

Query: 4616 TKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
               A+AP     P+K  + V  G  +   CK    P     W KGD  ++  +   +   
Sbjct: 296  --VASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISL--- 350

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
             ++  L+I+     D G Y C+A N  G+      L VT+P +    P+     D+ V E
Sbjct: 351  LNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPS---NMDVSVGE 407

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPD---FQMIHEGNNAVLLIGNTYEEDTGTF 4791
                  + Q    +     W   GAL     D   F+ +   ++  L+I N   + +G +
Sbjct: 408  SVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKY 467

Query: 4792 TCRATTAAGQVETSAKLVVK 4811
             C   T    V ++A L+V+
Sbjct: 468  VCMVQTGVDSVSSAADLIVR 487



 Score = 77.0 bits (181), Expect = 2e-12
 Identities = 66/257 (25%), Positives = 106/257 (41%), Gaps = 19/257 (7%)

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            V+ D R  + +E G   L I +  P D G Y CV  +    AR     V+  P       
Sbjct: 58   VEEDSRRFVSQETGH--LYISKVEPSDVGNYTCVVTSMVTNAR-----VLGSPTPLVLRS 110

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                    P   ++  +    A+G  ++  C  +G P+P + W + D L   SK  ++ +
Sbjct: 111  DGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSK-IKLRK 169

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
             +    L I     ED G Y+C+A NS G+     +L          L     ++D+ + 
Sbjct: 170  FSG--VLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQL-----IKDVEIA 222

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                  ++ + + K KP+ +WL+ GA +      Q+     N  L I N    D+G F C
Sbjct: 223  VEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQI----ENGALTISNLSVTDSGMFQC 278

Query: 4794 RATTAAGQVETSAKLVV 4810
             A    G V +SA+L V
Sbjct: 279  IAENKHGLVYSSAELKV 295



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 49/181 (27%), Positives = 87/181 (48%), Gaps = 14/181 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P +V++ +D ++       ++CR +G+P P   W  N   +  +   +I   E+G  AL 
Sbjct: 210 PHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQI---ENG--ALT 264

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER--FSTLNVREGEPVV 509
           I+N++++DSG+  C+A NK G       L V+      AP F +      + V+ G  V 
Sbjct: 265 ISNLSVTDSGMFQCIAENKHGLVYSSAELKVVAS----APDFSKNPMKKLVQVQVGSLVS 320

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L+ +   +P    +W+K  V +  +  + +  DGG    ++ +A   DA  Y C A+N  
Sbjct: 321 LDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKA---DAGTYTCMAENQF 377

Query: 570 G 570
           G
Sbjct: 378 G 378



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 83/375 (22%), Positives = 140/375 (37%), Gaps = 35/375 (9%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            W    +P     D +         L I +V   D   +  V  +    A+   +      
Sbjct: 49   WIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVL 108

Query: 4504 RRQGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
            R  G  G   P   +   + +    G  V+L+    G     + W ++         +KI
Sbjct: 109  RSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGL---PFSSKI 165

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
                 +  L I     +D+G YEC+A NS G+                          A 
Sbjct: 166  KLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYY----------------AK 209

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P  ++ +KD  +A   ++ + C+  GKP P+ +W K    +   +  Q+   A    L I
Sbjct: 210  PHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGA----LTI 265

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKV--TQPDQADNLPALTPLRDIV-VYEGQPAQ 4739
            S     D G ++C+A N  G V  +A+LKV  + PD + N     P++ +V V  G    
Sbjct: 266  SNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKN-----PMKKLVQVQVGSLVS 320

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
               +  +  +    W +    + E     ++++G    L I N  + D GT+TC A    
Sbjct: 321  LDCKPRASPRALSSWKKGDVSVQEHERISLLNDGG---LKIANVTKADAGTYTCMAENQF 377

Query: 4800 GQVETSAKLVVKSKT 4814
            G+   +  LVV   T
Sbjct: 378  GKANGTTHLVVTEPT 392



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 45/174 (25%), Positives = 74/174 (42%), Gaps = 13/174 (7%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G   + +C   G P P++ W  +D      ++ KI + +     L I N    D+G   
Sbjct: 133 KGSTVKLECFALGNPIPQINWRRSDGL---PFSSKIKLRKFSG-VLEIPNFQQEDAGSYE 188

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C+A N  G+   + RL    K     P +V+    + +   + +    RA G P P   W
Sbjct: 189 CIAENSRGKNVARGRLTYYAK-----PHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRW 243

Query: 525 QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            K+G  ++   E R   + GA  L I     +D+  +QC A+N  G   + A L
Sbjct: 244 LKNGAALV--LEERTQIENGA--LTISNLSVTDSGMFQCIAENKHGLVYSSAEL 293



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 50/163 (30%), Positives = 72/163 (44%), Gaps = 16/163 (9%)

Query: 425 WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV-------ARNKSGETAFQ 477
           W  N+     + + +  V++   H L I+ V  SD G  TCV       AR     T   
Sbjct: 49  WIFNEYPSFVEEDSRRFVSQETGH-LYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLV 107

Query: 478 CRLNVIEKEQVVAPKFVERF-STLNVREGEPVVLNARAVGTPTPRITWQK-DGVPIIPNP 535
            R + +  E    PK   +F  TL   +G  V L   A+G P P+I W++ DG+P     
Sbjct: 108 LRSDGVMGEY--EPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKI 165

Query: 536 ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           +LR  +      L+IP  +  DA  Y+C A+N  G    R RL
Sbjct: 166 KLRKFS----GVLEIPNFQQEDAGSYECIAENSRGKNVARGRL 204



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 57/218 (26%), Positives = 90/218 (41%), Gaps = 18/218 (8%)

Query: 369 QYITDTQQRETEERIEISEKALAPQFVKVCQDR--DVTEGKMTRFDCRVTGRPYPEVTWF 426
           Q I + +        E+   A AP F K    +   V  G +   DC+    P    +W 
Sbjct: 277 QCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWK 336

Query: 427 INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
             D  +++ +    L+N+ G   L I NVT +D+G  TC+A N+ G+      L V E  
Sbjct: 337 KGDVSVQE-HERISLLNDGG---LKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPT 392

Query: 487 QV-VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI--TWQKDG-VPIIPNPELRIHTD 542
           ++ +AP      S ++V  GE V+L  +    P   I  TW  +G +             
Sbjct: 393 RITLAP------SNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKV 446

Query: 543 GGASTLD--IPRAKASDAAWYQCTAQNVAGSTATRARL 578
           GG+S+ D  I   +   +  Y C  Q    S ++ A L
Sbjct: 447 GGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADL 484



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 17/186 (9%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P +  + KD V+I+     ++E     +G       W  NG  +    R +         
Sbjct: 210  PHWVQLIKD-VEIAVEDSLYWECRA--SGKPKPSYRWLKNGAALVLEERTQIENG----A 262

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTH-IQNIEGLKDGQS 3166
            L I     TDSG + C A NK G    S +L+ V       P F+ + ++ +  ++ G  
Sbjct: 263  LTISNLSVTDSGMFQCIAENKHGLVYSSAELKVV----ASAPDFSKNPMKKLVQVQVGSL 318

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               +C   P   P     W      ++   RI  ++D G   L IA     D+G Y C A
Sbjct: 319  VSLDCK--PRASPRALSSWKKGDVSVQEHERISLLNDGG---LKIANVTKADAGTYTCMA 373

Query: 3227 YNKYGE 3232
             N++G+
Sbjct: 374  ENQFGK 379



 Score = 48.4 bits (110), Expect = 6e-04
 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 7/112 (6%)

Query: 1701 SAQDEVITQAPVFTM-PMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            SA+ +V+  AP F+  PMK  ++V        + +  P   P+    W +  V ++   R
Sbjct: 290  SAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCK--PRASPRALSSWKKGDVSVQEHER 347

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
            ++ ++D G   L +  V   D+GTYTC A N+ G+A  ++ L V     + L
Sbjct: 348  ISLLNDGG---LKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITL 396



 Score = 45.2 bits (102), Expect = 0.006
 Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 4/87 (4%)

Query: 285 FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPN 344
           ++ + SG P+P   W KNG  L+   + +I     +  L + N   +DSG +  +AEN +
Sbjct: 229 WECRASGKPKPSYRWLKNGAALVLEERTQI----ENGALTISNLSVTDSGMFQCIAENKH 284

Query: 345 GCIVTSGYLAVESPTESYVQDQRSQYI 371
           G + +S  L V +    + ++   + +
Sbjct: 285 GLVYSSAELKVVASAPDFSKNPMKKLV 311



 Score = 44.8 bits (101), Expect = 0.008
 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 264 SPPKIAQKPRNS--KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           S P  ++ P     ++Q G+      +   +PR   +W K G   ++  +HE I+  N  
Sbjct: 298 SAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGD--VSVQEHERISLLNDG 354

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
            L++ N  K+D+G YT +AEN  G    + +L V  PT
Sbjct: 355 GLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPT 392



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 15/181 (8%)

Query: 3048 PEFT-TVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            P+F+    K +V +  G +   +    P      +  W     +++   RI  +   G+ 
Sbjct: 300  PDFSKNPMKKLVQVQVGSLVSLDCK--PRASPRALSSWKKGDVSVQEHERISLLNDGGLK 357

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +  +  TK  D+GTY+C A N++G+A  +  L   + +     R T    N++ +  G+S
Sbjct: 358  IANV--TKA-DAGTYTCMAENQFGKANGTTHLVVTEPT-----RITLAPSNMD-VSVGES 408

Query: 3167 AHFECTVVPVDDPDMKIEWYHNG---QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
                C V      D+   WY NG      +  +  + V       L I   Q   SG+YV
Sbjct: 409  VILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYV 468

Query: 3224 C 3224
            C
Sbjct: 469  C 469



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 2371 VTRQRPVFTQ-PLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH 2429
            V    P F++ P++ +  +Q G     DC+  P   P     W + +  +++  RI+  +
Sbjct: 295  VVASAPDFSKNPMKKLVQVQVGSLVSLDCK--PRASPRALSSWKKGDVSVQEHERISLLN 352

Query: 2430 DFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            D G   + I++V   D G Y C A N  G+
Sbjct: 353  DGG---LKIANVTKADAGTYTCMAENQFGK 379



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 6/94 (6%)

Query: 909  PEF-KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            P+F K P+K  + ++ G     + +  P         W K    V+   RI+   + G  
Sbjct: 300  PDFSKNPMKKLVQVQVGSLVSLDCK--PRASPRALSSWKKGDVSVQEHERISLLNDGG-- 355

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             L I +VT  DAG YTC A N  G+A  + +L +
Sbjct: 356  -LKIANVTKADAGTYTCMAENQFGKANGTTHLVV 388



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 31/108 (28%), Positives = 41/108 (37%), Gaps = 5/108 (4%)

Query: 3701 IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYI 3760
            +K  + V  G  V  DC+  P   P     W           R+  LND G   L I  +
Sbjct: 307  MKKLVQVQVGSLVSLDCK--PRASPRALSSWKKGDVSVQEHERISLLNDGG---LKIANV 361

Query: 3761 YARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
               DAG YTC A N++G A  T  +  +    I L         GE +
Sbjct: 362  TKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESV 409



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 6/96 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P +   +KD+ +A   + ++E R    G PK    WL+NG  +    R  T  + G  AL
Sbjct: 210  PHWVQLIKDVEIAVEDSLYWECRAS--GKPKPSYRWLKNGAALVLEER--TQIENG--AL 263

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             +  ++  DSG + C A N+ G   +S+ L V + A
Sbjct: 264  TISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASA 299



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           +T   V  S   +    D  +G   P    Q P      +G+  + +    GNP P++ W
Sbjct: 94  VTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINW 153

Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
            +    L  S+K ++        L + N Q+ D+G Y  +AEN  G  V  G L
Sbjct: 154 -RRSDGLPFSSKIKLRKFSG--VLEIPNFQQEDAGSYECIAENSRGKNVARGRL 204



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 7/97 (7%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN-GRPFATGSRVHTLNDFGFI 3753
            P+  V+  + +   +G  V  +C    +G+P  +I+W  + G PF++  ++   +     
Sbjct: 119  PKIEVQFPETLPAAKGSTVKLECFA--LGNPIPQINWRRSDGLPFSSKIKLRKFSG---- 172

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
             L+I      DAG Y C A N  G      ++T  AK
Sbjct: 173  VLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAK 209



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 45/201 (22%), Positives = 72/201 (35%), Gaps = 13/201 (6%)

Query: 3050 FTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLE 3109
            F T  +  V + EGQ         P   + +   W +N          R   +     L 
Sbjct: 16   FKTKMRSTVSVREGQGVVLLCGPPPHSGE-LSYAWIFNEYPSFVEEDSRRFVSQETGHLY 74

Query: 3110 ILGTKTTDSGTYSCRATNKWGQAEI-SVKLECVDKSKG----QKPRFTTHIQNIEGLKDG 3164
            I   + +D G Y+C  T+    A +       V +S G     +P+             G
Sbjct: 75   ISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKG 134

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHN-GQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
             +   EC  +   +P  +I W  + G P     +++  S     VL+I   Q  D+G Y 
Sbjct: 135  STVKLECFAL--GNPIPQINWRRSDGLPFSSKIKLRKFSG----VLEIPNFQQEDAGSYE 188

Query: 3224 CRAYNKYGEDFTRATINCYGK 3244
            C A N  G++  R  +  Y K
Sbjct: 189  CIAENSRGKNVARGRLTYYAK 209



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 6/100 (6%)

Query: 2638 VQQAPIFTTH-LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            V  AP F+ + +K   ++  G  V L+ +  PR  P     W K  V++    R+    D
Sbjct: 296  VASAPDFSKNPMKKLVQVQVGSLVSLDCK--PRASPRALSSWKKGDVSVQEHERISLLND 353

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             GL    I ++   D+G YTC A N  G+A  T  + + +
Sbjct: 354  GGL---KIANVTKADAGTYTCMAENQFGKANGTTHLVVTE 390



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 6/92 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P +     D+ ++   S ++ECR       S R  W  NG  L+   R +  N      L
Sbjct: 210  PHWVQLIKDVEIAVEDSLYWECRASGKPKPSYR--WLKNGAALVLEERTQIENG----AL 263

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I  +   D+G++ C A N+HG    S +L+V
Sbjct: 264  TISNLSVTDSGMFQCIAENKHGLVYSSAELKV 295



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 12/133 (9%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            VLEI   +  D+G+Y C A N  G+     +L         KP +   I+++E +    S
Sbjct: 173  VLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYY-----AKPHWVQLIKDVE-IAVEDS 226

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
             ++EC       P  +  W  NG  +    R + + +    + +++ T   DSG + C A
Sbjct: 227  LYWECRASGKPKPSYR--WLKNGAALVLEERTQ-IENGALTISNLSVT---DSGMFQCIA 280

Query: 3227 YNKYGEDFTRATI 3239
             NK+G  ++ A +
Sbjct: 281  ENKHGLVYSSAEL 293



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 6/99 (6%)

Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
           Y  P ++  +K V       +++E R    G P     WLKNG ++    R T I     
Sbjct: 207 YAKPHWVQLIKDVEIAVEDSLYWECRAS--GKPKPSYRWLKNGAALVLEER-TQIENG-- 261

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            +L + +L++ DSG + C A +  G+  + A L V   A
Sbjct: 262 -ALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASA 299



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 6/88 (6%)

Query: 1849 QLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILT 1908
            QL    +++   S ++ECR    P P+ R  W  NG  L    R +  N     AL I  
Sbjct: 214  QLIKDVEIAVEDSLYWECRASGKPKPSYR--WLKNGAALVLEERTQIEN----GALTISN 267

Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            +   DSG + C A N  G   SS  L V
Sbjct: 268  LSVTDSGMFQCIAENKHGLVYSSAELKV 295



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 6/112 (5%)

Query: 1171 EISKSKPVFVQ-PLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            ++  S P F + P+     V  G  + L+C+  P   P     W     SV    R    
Sbjct: 294  KVVASAPDFSKNPMKKLVQVQVGSLVSLDCK--PRASPRALSSWKKGDVSVQEHERISLL 351

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281
             D G   L I + T AD G YT  A N  G A+ +  + V E + I     N
Sbjct: 352  NDGG---LKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSN 400



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 6/101 (5%)

Query: 770 PQFIR-PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
           P F + P++ L ++Q G     + +  P + P     W K    +    RI S+ N G  
Sbjct: 300 PDFSKNPMKKLVQVQVGSLVSLDCK--PRASPRALSSWKKGDVSVQEHERI-SLLNDG-- 354

Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVT 869
            L I ++   DAG+YT  A N+ G+A  T  + V   + +T
Sbjct: 355 GLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRIT 395



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 29/129 (22%), Positives = 56/129 (43%), Gaps = 7/129 (5%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQ 1335
            + + Q E A    + + + +R     R  +T    P + + + ++E     +++ ECR  
Sbjct: 176  IPNFQQEDA-GSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRAS 234

Query: 1336 PVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
              G       W  NG  +    R     + +  AL + ++   DSG++ C A N+ G   
Sbjct: 235  --GKPKPSYRWLKNGAALVLEERT----QIENGALTISNLSVTDSGMFQCIAENKHGLVY 288

Query: 1396 TSCALRVIA 1404
            +S  L+V+A
Sbjct: 289  SSAELKVVA 297



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 27/102 (26%), Positives = 40/102 (39%), Gaps = 3/102 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+F+  P   ++     +       P         W      +    R+  +ND G   L
Sbjct: 300  PDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGG---L 356

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            +I  V + DAG YTC A N+ G+A  +  L V     I L P
Sbjct: 357  KIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAP 398



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 8/112 (7%)

Query: 48  MTTQVESSGDRQPITA---GRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVS 104
           M T     G   P+     G  GE  P I  Q  +    A+G   K E    GNP P ++
Sbjct: 93  MVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQIN 152

Query: 105 WTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           W R+   L   +K  +R  + +G   L I      D G Y C A N  G+ +
Sbjct: 153 W-RRSDGLPFSSKIKLR--KFSG--VLEIPNFQQEDAGSYECIAENSRGKNV 199



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 7/94 (7%)

Query: 2906 TEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSD 2965
            T Y KP W+  I      VE   L+ E +   K  P  +  W  NG  L    R ++ + 
Sbjct: 205  TYYAKPHWVQLIKDVEIAVEDS-LYWECRASGKPKPSYR--WLKNGAALVLEERTQIEN- 260

Query: 2966 FGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
             G +T+  + V   DSG++ C A NK G  ++S+
Sbjct: 261  -GALTISNLSV--TDSGMFQCIAENKHGLVYSSA 291



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 7/93 (7%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P +   +K  +  VE   +Y E +   +  P+ +  W KNG  L    R +   + G +T
Sbjct: 210  PHWVQLIKDVEIAVEDS-LYWECRASGKPKPSYR--WLKNGAALVLEERTQ--IENGALT 264

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +S  +L   DSG++ C A N  G   S+A +K+
Sbjct: 265  IS--NLSVTDSGMFQCIAENKHGLVYSSAELKV 295



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G     + K R +P  + SW +    + E  + S+       D  L I  +   D G YT
Sbjct: 316 GSLVSLDCKPRASPRALSSWKKGDVSVQEHERISL-----LNDGGLKIANVTKADAGTYT 370

Query: 146 CTARNQYGEA 155
           C A NQ+G+A
Sbjct: 371 CMAENQFGKA 380



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 9/96 (9%)

Query: 908  KPEFKTPIKD-QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            KP +   IKD +I++++    ++E R    G       WLK+G  +    R  T    G 
Sbjct: 209  KPHWVQLIKDVEIAVEDS--LYWECRAS--GKPKPSYRWLKNGAALVLEER--TQIENG- 261

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
             ALTI +++V D+G + C A N  G   +SA L +V
Sbjct: 262  -ALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVV 296



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
           +  GR    + P + Q+ K+   A   +  +E +  G P P   W +  A LV      +
Sbjct: 199 VARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALV------L 252

Query: 121 RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
               Q  + +L I  +   D G + C A N++G
Sbjct: 253 EERTQIENGALTISNLSVTDSGMFQCIAENKHG 285



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/96 (25%), Positives = 39/96 (40%), Gaps = 3/96 (3%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIP 4170
            P +V L   V +   +   + CR +G PKP   WL NG  +V   R ++    +   ++ 
Sbjct: 210  PHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLS 269

Query: 4171 KTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDY 4206
             T   D+G  + I             LKV+    D+
Sbjct: 270  VT---DSGMFQCIAENKHGLVYSSAELKVVASAPDF 302



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 7/91 (7%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P +   IKD +++     ++++CR      P+ R  W  NG       R    N     A
Sbjct: 210  PHWVQLIKD-VEIAVEDSLYWECRASGKPKPSYR--WLKNGAALVLEERTQIENG----A 262

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L I  +   D+G + C A NK G   ++A++
Sbjct: 263  LTISNLSVTDSGMFQCIAENKHGLVYSSAEL 293


>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
            precursor protein.
          Length = 1070

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 87/336 (25%), Positives = 134/336 (39%), Gaps = 30/336 (8%)

Query: 4480 VFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
            V A +AE+  G   C +ANL  + ++         PS+    Q+  +  G+   LD    
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQ 436

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
             T    V W +N   +  D R ++ + +GT  +  +E Y  D   Y C++   AG     
Sbjct: 437  ATPKPTVVWYRNQMLISEDSRFEVFK-NGTLRINSVEVY--DGTWYRCMSSTPAGSIEAQ 493

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            A   V L   K  P PQ      P + +E  K+  V         C   G+  PT++W +
Sbjct: 494  ARVQV-LEKLKFTPPPQ------PQQCMEFDKEATVP--------CSATGREKPTIKWER 538

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA-GRVTVAAKLKVTQPDQ 4717
             D    P        T +  TL  +    +D G+Y C+A N   G++    +L V     
Sbjct: 539  ADGSSLPEWV-----TDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFIT 593

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777
                P  T      VY+G  A  + +     KP IQW  +  ++  T     +H   N  
Sbjct: 594  FKVEPERT-----TVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGS 648

Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            L+I +   ED+G +TC A  +     T A L V  K
Sbjct: 649  LVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 92/414 (22%), Positives = 156/414 (37%), Gaps = 50/414 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-IL 4468
            P +         +    Q       DG P P  +W+R+  P+ +      HT S+K   L
Sbjct: 128  PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQ--SNHTVSSKERNL 185

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             +R    E S +++  A +  G A  S N  +          ++ P      Q+V V   
Sbjct: 186  TLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAP------QDVVVARY 239

Query: 4529 QLVRLDTKVTGTKPIDVYWL------KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            +      + +   P  + WL         +   P +R   +  +G  +LL+ +  P+++G
Sbjct: 240  EEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANG--SLLLTQVRPRNAG 297

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y C+     G      E  + L   +D P            + EP   ++   G     
Sbjct: 298  IYRCIGQGQRGPP-IILEATLHLAEIEDMP------------LFEP---RVFTAGSEERV 341

Query: 4643 SC-KIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            +C    G P P+V W + G +L    + +Q       + L ++     D G Y C A N 
Sbjct: 342  TCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKG-----HELVLANIAESDAGVYTCHAANL 396

Query: 4701 AGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
            AG+      + V        +P+ L   +D  + EG+P        +  KPT+ W R   
Sbjct: 397  AGQRRQDVNITVA------TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQM 450

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            LI E   F++     N  L I +    D   + C ++T AG +E  A++ V  K
Sbjct: 451  LISEDSRFEVF---KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 48/181 (26%), Positives = 80/181 (44%), Gaps = 14/181 (7%)

Query: 399 QDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457
           + R  T G   R  C    G P P V W      +R   + ++   + G H L++ N+  
Sbjct: 329 EPRVFTAGSEERVTCLPPKGLPEPSVWW--EHAGVRLPTHGRVY--QKG-HELVLANIAE 383

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           SD+GV TC A N +G+      + V        P ++++     + EG+P  L+     T
Sbjct: 384 SDAGVYTCHAANLAGQRRQDVNITV-----ATVPSWLKKPQDSQLEEGKPGYLDCLTQAT 438

Query: 518 PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
           P P + W ++ + I  +    +  +G   TL I   +  D  WY+C +   AGS   +AR
Sbjct: 439 PKPTVVWYRNQMLISEDSRFEVFKNG---TLRINSVEVYDGTWYRCMSSTPAGSIEAQAR 495

Query: 578 L 578
           +
Sbjct: 496 V 496



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 76/327 (23%), Positives = 125/327 (38%), Gaps = 53/327 (16%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D ++   + P   +KP++S+L+EG            P+P V W++N   +   ++ E+  
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVF- 461

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
              + TLR+ + +  D   Y  ++  P G I            E+  + Q  + +  T  
Sbjct: 462 --KNGTLRINSVEVYDGTWYRCMSSTPAGSI------------EAQARVQVLEKLKFTPP 507

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            + ++ +E  ++A  P                    C  TGR  P + W   D     ++
Sbjct: 508 PQPQQCMEFDKEATVP--------------------CSATGREKPTIKWERADGSSLPEW 547

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARN-KSGETAFQCRLNVIEKEQVVAPKFVE 495
               + + +G   L    VT  D+G  TC+A N   G+     +L V      V   F  
Sbjct: 548 ----VTDNAG--TLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTV-----AVFITFKV 596

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQ-KDGV--PIIPNPELRIHTDGGASTLDIPR 552
                 V +G   +L   A G P P I W+ KD +  P    P + I  +G   +L I  
Sbjct: 597 EPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNG---SLVIHD 653

Query: 553 AKASDAAWYQCTAQNVAGSTATRARLY 579
               D+  Y C A N      T A LY
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLY 680



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 70/310 (22%), Positives = 120/310 (38%), Gaps = 44/310 (14%)

Query: 266 PKIAQKPRN-SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P + + P + +++Q       +  + G+PRP   WF++G  L +   +  +++     L 
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERN-LT 186

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +R      SG Y+  A +  G   +S    +    ES+                   R+ 
Sbjct: 187 LRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFA------------------RV- 227

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR---QIRDDYNHKIL 441
                LAPQ V V +  +        F C+ + +P P + W   D      R    H   
Sbjct: 228 ----VLAPQDVVVARYEEAM------FHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRR 277

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTL 500
                N +L++T V   ++G+  C+ + + G     +  L++ E E +  P F  R  T 
Sbjct: 278 ATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM--PLFEPRVFTA 335

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
                E  V      G P P + W+  GV +  +   R++  G    L +     SDA  
Sbjct: 336 G---SEERVTCLPPKGLPEPSVWWEHAGVRLPTHG--RVYQKG--HELVLANIAESDAGV 388

Query: 561 YQCTAQNVAG 570
           Y C A N+AG
Sbjct: 389 YTCHAANLAG 398



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 86/392 (21%), Positives = 155/392 (39%), Gaps = 45/392 (11%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF-VEDSAVFAAVA-E 4486
            R EVE  G P+  + W  +  P++++       F+  S L    V  ++DS  F  VA +
Sbjct: 52   RCEVEAPG-PVH-VYWLLDGAPVQDTE----RRFAQGSSLSFAAVDRLQDSGTFQCVARD 105

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            +  G    SAN     K  +  G +V       A    +     V L   + G       
Sbjct: 106  DVTGEEARSANASFNIKWIEA-GPVV---LKHPASEAEIQPQTQVTLRCHIDGHPRPTYQ 161

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W ++G  +     N  +       L +  A P+ SG Y C A ++ G+A       +S+ 
Sbjct: 162  WFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSI- 219

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK--LIK 4664
                       A  +   ++   +D +VA  +   F C+   +P P++QW   D+  +  
Sbjct: 220  -----------ADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITN 268

Query: 4665 PSK--YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLKVTQPDQADNL 4721
             S+  + + +      +L +++  P + G Y+C+     G  + + A L + +    +++
Sbjct: 269  RSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAE---IEDM 325

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSK--IKPTIQWLREGALIPETPD-FQMIHEGNNAVL 4778
            P   P     V+     +  T +  K   +P++ W   G  +P     +Q  HE     L
Sbjct: 326  PLFEPR----VFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHE-----L 376

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            ++ N  E D G +TC A   AGQ      + V
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITV 408



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 11/133 (8%)

Query: 4414 TKKMQPCR--VFEHEQARFEVEFDGEPLPLIKWYREN---FPIKNSPDFQIHTFSTKSIL 4468
            T K++P R  V++   A  + E  G+P PLI+W  ++    P K  P  ++H F   S L
Sbjct: 593  TFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP--RMHIFQNGS-L 649

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK--RRQGRGGIVPPSFTLTAQNVNVT 4526
            +I  V  EDS  +  +A N        A L V +K    +  G   PP + +  Q + ++
Sbjct: 650  VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKM-IQTIGLS 708

Query: 4527 SGQLVRLDTKVTG 4539
             G  V     V G
Sbjct: 709  VGAAVAYIIAVLG 721



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 40/183 (21%), Positives = 66/183 (36%), Gaps = 7/183 (3%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
           F+K    +D  +G+     C V       V W ++   ++D    +     S + A +  
Sbjct: 34  FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDT-ERRFAQGSSLSFAAVDR 92

Query: 454 NVTLSDSGVVTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVER-FSTLNVREGEPVVLN 511
              L DSG   CVAR+  +GE A     +   K     P  ++   S   ++    V L 
Sbjct: 93  ---LQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               G P P   W +DG P + + +           L +  A    +  Y C A +  G 
Sbjct: 150 CHIDGHPRPTYQWFRDGTP-LSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQ 208

Query: 572 TAT 574
             +
Sbjct: 209 ACS 211



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/68 (35%), Positives = 33/68 (48%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDPK  ++W      ++ +     MH F   +L +  V PEDSG YTC A N      T 
Sbjct: 617  GDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTE 676

Query: 1798 STLFVQSK 1805
            + L+V  K
Sbjct: 677  APLYVVDK 684



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 4/67 (5%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE-QTGDVSLLIKQIGPGDEGE 143
           QG  A  + + +G+P P++ W + K  +++  K   R +  Q G  SL+I  + P D G 
Sbjct: 605 QGHTALLQCEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNG--SLVIHDVAPEDSGR 661

Query: 144 YTCTARN 150
           YTC A N
Sbjct: 662 YTCIAGN 668



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + +G TA   C     GDP   ++W   +++++ +    + H F   S+ I  V  ED G
Sbjct: 603  VYQGHTALLQCEA--QGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG 660

Query: 2448 VYMCRASN 2455
             Y C A N
Sbjct: 661  RYTCIAGN 668



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 6/90 (6%)

Query: 3982 QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKP-LLHKNRFTP-IYDFGYVAMNFGWVY 4039
            +T++ +  T   +C+    GDP   ++W   GK  +L   +  P ++ F   ++    V 
Sbjct: 600  RTTVYQGHTALLQCEAQ--GDPKPLIQW--KGKDRILDPTKLGPRMHIFQNGSLVIHDVA 655

Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            PEDSG Y C A N   +  T+A +    KP
Sbjct: 656  PEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            A LA  RR  V  T    P W+     + QL EG+  +L+   +    P   + WY N  
Sbjct: 394  ANLAGQRRQDVNITVATVPSWLKK-PQDSQLEEGKPGYLDCLTQATPKPT--VVWYRNQM 450

Query: 2953 VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            ++ + SRF++  + G + ++ V+VY  D   Y C +    G     + V    K
Sbjct: 451  LISEDSRFEVFKN-GTLRINSVEVY--DGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V +G      C   G P P + W   DR I D       ++   N +L+I +V   DSG 
Sbjct: 603 VYQGHTALLQCEAQGDPKPLIQWKGKDR-ILDPTKLGPRMHIFQNGSLVIHDVAPEDSGR 661

Query: 463 VTCVARNKSGETAFQCRLNVIEK 485
            TC+A N       +  L V++K
Sbjct: 662 YTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 62/285 (21%), Positives = 99/285 (34%), Gaps = 18/285 (6%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E  P + +     A             + G+P P   W R   PL +       +   + 
Sbjct: 125 EAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQS---NHTVSSK 181

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS----VYIQPEGXXXXXXXXXXXXXYRHVS 183
           + +L ++  GP   G Y+C A + +G+A  S    + I  E               R+  
Sbjct: 182 ERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARY-E 240

Query: 184 ETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
           E + H  +  Q   + Q     +   TN +         V      LL +V  R +   R
Sbjct: 241 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR 300

Query: 244 YVGESD--VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWF 300
            +G+      I  E    L  +    + + PR      G++ +   +   G P P V W 
Sbjct: 301 CIGQGQRGPPIILEATLHLAEIEDMPLFE-PR--VFTAGSEERVTCLPPKGLPEPSVWWE 357

Query: 301 KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             G RL     H  +    H  L + N  +SD+G YT  A N  G
Sbjct: 358 HAGVRL---PTHGRVYQKGH-ELVLANIAESDAGVYTCHAANLAG 398



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E  GD    ++W    R ++ +        F   +L I  V   D+G YTC A N+    
Sbjct: 614  EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 994  TTSANLTIVTKKDIIAESQHPG 1015
             T A L +V  K +  ES+ PG
Sbjct: 674  HTEAPLYVV-DKPVPEESEGPG 694



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/77 (27%), Positives = 37/77 (48%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           E  GDP   I+W    + ++ +     +  F   SL +  +  +DSG YTC A ++  + 
Sbjct: 614 EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 721 ETKAVLHVTPRATIERT 737
            T+A L+V  +   E +
Sbjct: 674 HTEAPLYVVDKPVPEES 690



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 17/125 (13%)

Query: 1288 IQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHL-----ECRLQPVGDQTM 1342
            +  L+D+       R+D+T  +A + + A  NI+ +E   V L     E  +QP    T+
Sbjct: 90   VDRLQDSGTFQCVARDDVTGEEA-RSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTL 148

Query: 1343 RV----------EWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            R           +WF +G P+  G         +   L L    PE SG+Y+C A +  G
Sbjct: 149  RCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFG 207

Query: 1393 EAVTS 1397
            +A +S
Sbjct: 208  QACSS 212



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 11/128 (8%)

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
            R  C + PK  P+  + W   G  LP+  R   VY  G   L +  +   D+G Y C A 
Sbjct: 340  RVTC-LPPKGLPEPSVWWEHAGVRLPTHGR---VYQKGH-ELVLANIAESDAGVYTCHAA 394

Query: 3908 NDFGEDFTKATISCKKLPDIILQ---NQVPRGMK-RSEALTQM--EATIKKYTSEVYLTE 3961
            N  G+      I+   +P  + +   +Q+  G     + LTQ   + T+  Y +++ ++E
Sbjct: 395  NLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISE 454

Query: 3962 DDLYDVDK 3969
            D  ++V K
Sbjct: 455  DSRFEVFK 462



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 1/95 (1%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q E + DP   I+W    ++L+          F   +L + DV   DSG YTC A N   
Sbjct: 612  QCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNL 3028
               T + +Y   K  + E ++ P      + IQ +
Sbjct: 672  IKHTEAPLYVVDKP-VPEESEGPGSPPPYKMIQTI 705



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 5/62 (8%)

Query: 1738 GDPKLRVEWLRNGVPIE--ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G P+   +W R+G P+    SN   +  +     L ++   PE SG Y+C A +  G+A 
Sbjct: 154  GHPRPTYQWFRDGTPLSDGQSNHTVSSKERN---LTLRPAGPEHSGLYSCCAHSAFGQAC 210

Query: 1796 TS 1797
            +S
Sbjct: 211  SS 212



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGK---PIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
            +G    L+C  Q  GD    ++W    +   P K G R    + F   +L +  V PEDS
Sbjct: 605  QGHTALLQCEAQ--GDPKPLIQWKGKDRILDPTKLGPRM---HIFQNGSLVIHDVAPEDS 659

Query: 1381 GVYTCQATNQLGEAVTSCALRVIAK 1405
            G YTC A N      T   L V+ K
Sbjct: 660  GRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++  P+   H  S  ++     V L   ++    P    +WF++G  L+ G +   T   
Sbjct: 124  IEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTY--QWFRDGTPLSDG-QSNHTVSS 180

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                L++     + SG+Y+C A +  G+A S+ +  +
Sbjct: 181  KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +W +DG P+       T  +     LT++      +G Y+C A++A GQA +S N T+
Sbjct: 161  QWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217


>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
            protein.
          Length = 1183

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 91/382 (23%), Positives = 160/382 (41%), Gaps = 49/382 (12%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P P+I W +E+  +  +    ++    K++ II  V   DS  +  +A+N  G    
Sbjct: 289  EGLPTPIIYWAKEDGMLPKNRT--VYKNFEKTLQIIH-VSEADSGNYQCIAKNALGAIHH 345

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            + ++ V+            P +    QN+ ++ G+   L  +  G     + WL NG  +
Sbjct: 346  TISVRVK----------AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPI 395

Query: 4555 Q--PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
            +  PD  ++ ++ D   T++      + S  Y+C A N  G    +A   V++ A     
Sbjct: 396  EIAPDDPSRKIDGD---TIIFSNVQERSSAVYQCNASNEYGYLLANA--FVNVLAE---- 446

Query: 4613 KPQTKAANAPPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
                     PP I+ P     +++A   A+   C   G PLPT++W+KG K    + +  
Sbjct: 447  ---------PPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAK--GSALHED 494

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            +    +  TL I  A  +  G Y CVA N  G       L++  P      P        
Sbjct: 495  IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYA----- 549

Query: 4731 VVYEGQPAQFKTQI--TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            VV  G    F+ ++     +  T+ WL++   +P    F +    +   L++ +  ++D+
Sbjct: 550  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV----DKDHLVVADVSDDDS 605

Query: 4789 GTFTCRATTAAGQVETSAKLVV 4810
            GT+TC A T    V  SA L V
Sbjct: 606  GTYTCVANTTLDSVSASAVLSV 627



 Score = 71.7 bits (168), Expect = 6e-11
 Identities = 77/308 (25%), Positives = 122/308 (39%), Gaps = 34/308 (11%)

Query: 4513 PPSFTL---TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
            PP+F      A N     G ++ L+    G     +YW K    +    +N+ + ++   
Sbjct: 261  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLP---KNRTVYKNFEK 317

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            TL I+     DSG Y+C+A N+ G             A       + KAA   P  I   
Sbjct: 318  TLQIIHVSEADSGNYQCIAKNALG-------------AIHHTISVRVKAA---PYWITAP 361

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
            ++ +++ G+     C+  G P P + W      I+ +     SR  D  T+  S      
Sbjct: 362  QNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDGDTIIFSNVQERS 420

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV-VYEGQPAQFKTQITSKI 4748
               Y+C A N  G +   A + V     A+    LTP   +  V   +PA          
Sbjct: 421  SAVYQCNASNEYGYLLANAFVNVL----AEPPRILTPANTLYQVIANRPALLDCAFFGSP 476

Query: 4749 KPTIQWLR--EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
             PTI+W +  +G+ + E  D  ++HE  N  L I    ++ TGT+TC A    G  +   
Sbjct: 477  LPTIEWFKGAKGSALHE--DIYVLHE--NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV 532

Query: 4807 KLVVKSKT 4814
             L +K  T
Sbjct: 533  HLEIKDPT 540



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 72/283 (25%), Positives = 115/283 (40%), Gaps = 18/283 (6%)

Query: 291 GNPRPRVTWFKNG-QRLINSNKHEIITTHNHTTLRVRNTQKSDSGH-YTLLAE-NPNGCI 347
           G P P + W  N  QRL  S +   ++   +  L   N    D+   Y   A  N    I
Sbjct: 166 GLPPPIIFWMDNSFQRLPQSER---VSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTI 222

Query: 348 VTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407
                ++V+  +   + D  +  ++DT+    +   E     L P+      +++   G 
Sbjct: 223 QQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE--GNASNKEELRGN 280

Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467
           +   +C   G P P + W   D  +  +      V ++    L I +V+ +DSG   C+A
Sbjct: 281 VLSLECIAEGLPTPIIYWAKEDGMLPKNRT----VYKNFEKTLQIIHVSEADSGNYQCIA 336

Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
           +N  G  A    ++V  K    AP ++     L +  GE   L  RA G P PRI+W  +
Sbjct: 337 KNALG--AIHHTISVRVK---AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTN 391

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           GVPI   P+       G  T+     +   +A YQC A N  G
Sbjct: 392 GVPIEIAPDDPSRKIDG-DTIIFSNVQERSSAVYQCNASNEYG 433



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 92/432 (21%), Positives = 168/432 (38%), Gaps = 48/432 (11%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFE-HEQARFEVEFDGEPLPLIKWYRE--NFPIKNSPDF 4457
            +E P+   +PP  T++     + +  E    + E  G+P P   W R   +F I   P  
Sbjct: 30   LEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLV 89

Query: 4458 QIHTFS-TKSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPS 4515
             +   + T  I I+ +   E    V+   A N  G A  S N+VV   R         P 
Sbjct: 90   TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVRPSRS--------PL 140

Query: 4516 FTLTA-QNVNVTSGQLVRLDTKVT-GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            +T    + + + SGQ + L  +   G  P  ++W+ N  +  P  +++ + +     L  
Sbjct: 141  WTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLP--QSERVSQGLNGDLYF 198

Query: 4574 LEAYPQDSGK-YECVA----INSAGEARCDAECVVSLPATKDKPKPQTK---------AA 4619
                P+D+ + Y C A      +  + +  +  V+S+    D                + 
Sbjct: 199  SNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSR 258

Query: 4620 NAPPEIIEP---LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
              PP  + P     +K    G  +   C   G P P + W K D ++  ++    +    
Sbjct: 259  ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF--- 315

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRV--TVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
            E TL+I      D G+Y+C+A N+ G +  T++ ++K            +T  +++V+  
Sbjct: 316  EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP-------YWITAPQNLVLSP 368

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G+      +     KP I WL  G  I   PD     + +   ++  N  E  +  + C 
Sbjct: 369  GEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDGDTIIFSNVQERSSAVYQCN 427

Query: 4795 ATTAAGQVETSA 4806
            A+   G +  +A
Sbjct: 428  ASNEYGYLLANA 439



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 53/200 (26%), Positives = 84/200 (42%), Gaps = 16/200 (8%)

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR---DDYNHK 439
           I +  KA AP ++   Q+  ++ G+     CR  G P P ++W  N   I    DD + K
Sbjct: 347 ISVRVKA-APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 405

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           I         ++ +NV    S V  C A N+ G       +NV+ +     P+ +   +T
Sbjct: 406 I-----DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP----PRILTPANT 456

Query: 500 L-NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           L  V    P +L+    G+P P I W K       + ++ +  + G  TL+IP A+    
Sbjct: 457 LYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDST 514

Query: 559 AWYQCTAQNVAGSTATRARL 578
             Y C A+N  G       L
Sbjct: 515 GTYTCVARNKLGMAKNEVHL 534



 Score = 51.6 bits (118), Expect = 7e-05
 Identities = 59/244 (24%), Positives = 88/244 (36%), Gaps = 20/244 (8%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP   T    +  +   + A  + +    G     IEWF   K       I  ++  G  
Sbjct: 447  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 502

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             LEI   +   +GTY+C A NK G A+  V LE  D      P +         ++ G  
Sbjct: 503  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD------PTWIVKQPEYAVVQRGSM 556

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              FEC V       + + W  + + +    R  TV     VV D++   + DSG Y C A
Sbjct: 557  VSFECKVKHDHTLSLTVLWLKDNRELPSDERF-TVDKDHLVVADVS---DDDSGTYTCVA 612

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
                      A ++         +    D L K  +L    G    +P T      KFI 
Sbjct: 613  NTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPIT------KFII 666

Query: 3287 QIQD 3290
            + +D
Sbjct: 667  EYED 670



 Score = 49.6 bits (113), Expect = 3e-04
 Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 4/93 (4%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V + G  + FEC V+     +L + W  +N+ LPS  R+    D   V+ D++   ++DS
Sbjct: 550  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVS---DDDS 605

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQ 2876
            G YTC A  +  S + S  L      N  FD +
Sbjct: 606  GTYTCVANTTLDSVSASAVLSVVDVPNPPFDLE 638



 Score = 48.0 bits (109), Expect = 8e-04
 Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 21/201 (10%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSIL 4468
            P I T      +V  +  A  +  F G PLP I+W++       +   + +H   T  I 
Sbjct: 448  PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIP 507

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            + ++   + +  +  VA N+ G AK   +L +++          P       +   V  G
Sbjct: 508  VAQK---DSTGTYTCVARNKLGMAKNEVHLEIKD----------PTWIVKQPEYAVVQRG 554

Query: 4529 QLVRLDTKV--TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             +V  + KV    T  + V WLK+ +++  D R  + ++D    L++ +    DSG Y C
Sbjct: 555  SMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV-DKD---HLVVADVSDDDSGTYTC 610

Query: 4587 VAINSAGEARCDAE-CVVSLP 4606
            VA  +       A   VV +P
Sbjct: 611  VANTTLDSVSASAVLSVVDVP 631



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 16/197 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RPP F T   +  +  E +        I  G  + +I W      +  +   RTVY    
Sbjct: 260  RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN---RTVYKNFE 316

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              L+I+     DSG Y C A N  G     ISV+++         P + T  QN+  L  
Sbjct: 317  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA-------PYWITAPQNLV-LSP 368

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+     C      +P  +I W  NG P+  +    +    G  ++  +  Q   S  Y 
Sbjct: 369  GEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQ 425

Query: 3224 CRAYNKYGEDFTRATIN 3240
            C A N+YG     A +N
Sbjct: 426  CNASNEYGYLLANAFVN 442



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 265 PPKIAQKPRNSKLQEGAD--AQFQVQLSGNPRPRVTWFKNGQRLINSNKHE-IITTHNHT 321
           PP+I   P N+  Q  A+  A       G+P P + WFK  +    S  HE I   H + 
Sbjct: 447 PPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENG 502

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           TL +   QK  +G YT +A N  G      +L ++ PT
Sbjct: 503 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 540



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP +  A  N+    G +  L CR    G+   R+ W  NG PI+      P+ +
Sbjct: 349  VRVKAAPYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPD-DPSRK 405

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
             D   +   +V    S VY C A+N+ G  + +  + V+A+   IL
Sbjct: 406  IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRIL 451



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 75/330 (22%), Positives = 118/330 (35%), Gaps = 31/330 (9%)

Query: 3043 DTGRPPEFTTVF-KD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGK--TIEASHRIR 3098
            D  +PP  T    KD I+D  E  +   EA     G       W  NG    I+    + 
Sbjct: 35   DLVQPPTITQQSPKDYIIDPRENIVIQCEAK----GKPPPSFSWTRNGTHFDIDKDPLVT 90

Query: 3099 TVYAFGMVVLEIL--GTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ 3156
                 G +++ I+  G   T  G Y C A N+ G A   V    V +   + P +T    
Sbjct: 91   MKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA---VSNNIVVRPS-RSPLWTKEKL 146

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG-QPMRHSTRIKTVSDFGFVVLDIAYTQ 3215
                L+ GQS    C   P+  P   I W  N  Q +  S R+    +      ++    
Sbjct: 147  EPITLQSGQSLVLPCRP-PIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPED 205

Query: 3216 NHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPS 3275
              +  +Y+C  Y ++    T           + ++ L     A + + E   GA+     
Sbjct: 206  TRE--DYIC--YARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE-FYGAKSSRE- 259

Query: 3276 TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHR-YRTF 3334
                 PP F+T   + +   E +        +    P   + W      LP     Y+ F
Sbjct: 260  ----RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF 315

Query: 3335 HDFGIVILDILYCYEENSGEYECVATNKLG 3364
                   L I++  E +SG Y+C+A N LG
Sbjct: 316  EK----TLQIIHVSEADSGNYQCIAKNALG 341



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            + +  P +++ P  + +  GE     CR  G+PKPR+ WL NG
Sbjct: 350  RVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 392



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 7/117 (5%)

Query: 1167 YQIEEISKSKPVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            Y  +   +  P F+ P  N     E  G  + LEC  E  G PT  + W      +    
Sbjct: 252  YGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE--GLPTPIIYWAKEDGMLP--- 306

Query: 1225 RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281
            + +T Y      L IIH + AD+G Y   A N LG+ H +  VRV      +T  QN
Sbjct: 307  KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN 363



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 4/115 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P ++        ++ G    FEC+V+  +   LT+ W  + +++ +  R+    D   VA
Sbjct: 539  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA 598

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL 2223
             D+     +DSGTY C A   L     +  L V    N   D +  + L+K  QL
Sbjct: 599  -DV---SDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQL 649



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980
            ++ G    FE +++     +L V WLKD R + +  R T   +     L +  V+  D+G
Sbjct: 551  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 606

Query: 981  HYTCRAYNAIGQATTSANLTIV 1002
             YTC A   +   + SA L++V
Sbjct: 607  TYTCVANTTLDSVSASAVLSVV 628



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            AEPP+ +T    + +++  + A  +        P   +EWF   K           H+ G
Sbjct: 445  AEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG 502

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
               L+I    ++++G Y CVA NKLG    + +L+
Sbjct: 503  T--LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 535



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 9/133 (6%)

Query: 3813 RGRISDAPKEEPI-VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            R ++  A  E  + +  P   + Q +   V+    V FEC+V+      L + W ++ + 
Sbjct: 522  RNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRE 581

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP----DI 3927
            LPS  R+    D     L +  V  +DSG Y C A          A +S   +P    D+
Sbjct: 582  LPSDERFTVDKD----HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDL 637

Query: 3928 ILQNQVPRGMKRS 3940
             L +Q+ + ++ S
Sbjct: 638  ELTDQLDKSVQLS 650



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            +  G    FE +V+    L++TV W  + +++ S  R     D     L +A V  +DSG
Sbjct: 551  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 606

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
             YT VA         SA ++V
Sbjct: 607  TYTCVANTTLDSVSASAVLSV 627



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 272 PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS 331
           P+N  L  G D     + +GNP+PR++W  NG   I     +     +  T+   N Q+ 
Sbjct: 361 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVP-IEIAPDDPSRKIDGDTIIFSNVQER 419

Query: 332 DSGHYTLLAENPNGCIVTSGYLAV 355
            S  Y   A N  G ++ + ++ V
Sbjct: 420 SSAVYQCNASNEYGYLLANAFVNV 443



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 41/159 (25%), Positives = 67/159 (42%), Gaps = 12/159 (7%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP   T  + L  +  N  A  +C           +EWF   K       +  +++ G  
Sbjct: 447  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 502

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ-- 3673
             LEI    +   G YTC A N+ G A     L++K    I+ +P+     +    S +  
Sbjct: 503  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 562

Query: 3674 -KLEETLHKREEITIED--EKPNPPRFTVEIKDNIDVPE 3709
             K + TL     + ++D  E P+  RFTV+ KD++ V +
Sbjct: 563  VKHDHTL-SLTVLWLKDNRELPSDERFTVD-KDHLVVAD 599



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 4/86 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PPR          V    P   DC     G P   I+WF   +  A    ++ L++ G  
Sbjct: 447  PPRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWFKGAKGSALHEDIYVLHENG-- 502

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSA 3779
             L+I        G YTC A NK G A
Sbjct: 503  TLEIPVAQKDSTGTYTCVARNKLGMA 528



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 8/90 (8%)

Query: 2372 TRQRP-VFTQPLQNIDNIQE--GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428
            +R+RP  F  P  N  N +E  G     +C  I  G PT  + W + + ++  +  + K 
Sbjct: 257  SRERPPTFLTPEGNASNKEELRGNVLSLEC--IAEGLPTPIIYWAKEDGMLPKNRTVYKN 314

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             +    ++ I HV + D G Y C A N LG
Sbjct: 315  FE---KTLQIIHVSEADSGNYQCIAKNALG 341



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 3/102 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P + T P +L+LS        CR     +   R+ W  NG P+       +    G  I+
Sbjct: 355  PYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 412

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
                V +R + +Y C A+N +G    +  + V      IL P
Sbjct: 413  -FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 453



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 43/170 (25%), Positives = 63/170 (37%), Gaps = 16/170 (9%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           DC   G P P + WF   +  +    H+ +     N  L I       +G  TCVARNK 
Sbjct: 469 DCAFFGSPLPTIEWF---KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 525

Query: 472 GETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTPRIT--WQKDG 528
           G    +  L + +   +V  P++        V+ G  V    +     T  +T  W KD 
Sbjct: 526 GMAKNEVHLEIKDPTWIVKQPEYAV------VQRGSMVSFECKVKHDHTLSLTVLWLKDN 579

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +P+ E R   D     L +      D+  Y C A     S +  A L
Sbjct: 580 RE-LPSDE-RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVL 625



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            IEWFK          +    + G  TL I   + D +G YTC A N LG A +   ++I+
Sbjct: 480  IEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 537

Query: 2736 DRHWLL 2741
            D  W++
Sbjct: 538  DPTWIV 543



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 4/78 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P ++ +      V  G  V FECK++     +L V W K+ + +    RF    D   VA
Sbjct: 539  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA 598

Query: 1504 LDIIDLIAEDSGIYTCRA 1521
             D+ D   +DSG YTC A
Sbjct: 599  -DVSD---DDSGTYTCVA 612



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           P I +Q  K+       N   + + +G P P  SWTR            +     TG + 
Sbjct: 40  PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 99

Query: 131 LLIKQIGPGD--EGEYTCTARNQYGEAIC-SVYIQP 163
           + I   G  +  EG Y CTARN+ G A+  ++ ++P
Sbjct: 100 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRP 135



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 8/100 (8%)

Query: 3829 PPKFIT-QIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            PP F+T +  +   EE  G  +  EC  E    P   I W +   +LP     RTVY   
Sbjct: 261  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPI--IYWAKEDGMLPKN---RTVYKNF 315

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              +L I++V   DSG Y C A N  G      ++  K  P
Sbjct: 316  EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 355



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G+PK R+ WL NGVPIE +    +    G   +    V    S  Y C A NE G
Sbjct: 380  GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYG 433



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + PR +T  N   ++   + A  +C     P P   +EW+   K           ++ G 
Sbjct: 446  EPPRILTPANTLYQVIANRPALLDCAFFGSPLPT--IEWFKGAKGSALHEDIYVLHENG- 502

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
              L+I     + +G YTC A N LG A + + L ++    I++  ++
Sbjct: 503  -TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEY 548



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-YRTTHDFGYV 2167
            P  LT   +L  +     A  +C       P  TI+WF  G K  A H      H+ G  
Sbjct: 448  PRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWF-KGAKGSALHEDIYVLHENG-- 502

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L+I     + +GTY C A NKLG A N   L++
Sbjct: 503  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI 536



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 4/105 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P +I +  +   +  G    FE ++       L V W  + ++LP   R+    D  +V+
Sbjct: 539  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVV 597

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQL 3386
             D+    +++SG Y CVA   L   S  A L      N   D +L
Sbjct: 598  ADVS---DDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLEL 639



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1589 IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSG 1648
            ++ G    FE ++      +L V W  +N+ L S  RFT   +   V  D+     +DSG
Sbjct: 551  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSD---DDSG 606

Query: 1649 TYTCRAINALGEAVTSGIAIV 1669
            TYTC A   L     S +  V
Sbjct: 607  TYTCVANTTLDSVSASAVLSV 627



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 7/110 (6%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVE-GQVLHLEGQVEPKNDPDLKIEWYFNG 2951
            AR   G   +    E   P WI+    E+ +V+ G ++  E +V+  +   L + W  + 
Sbjct: 521  ARNKLGMAKNEVHLEIKDPTWIVK-QPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDN 579

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + L    RF +  D     L + DV + DSG YTC A N   ++ ++S V
Sbjct: 580  RELPSDERFTVDKDH----LVVADVSDDDSGTYTCVA-NTTLDSVSASAV 624



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 13/162 (8%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V  G  +  EC+++     ++ V W  + R +    RF    D   V  D+   +  D+G
Sbjct: 551  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADV---SDDDSG 606

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ-NEQAIEQIQLL-----EDAARRTKQVR 1302
             YT  A   L S   SA++ V++  +   D +  +Q  + +QL      ++ +  TK + 
Sbjct: 607  TYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFII 666

Query: 1303 EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRV 1344
            E    M  P      H+   V GT    + +L P  + + RV
Sbjct: 667  EYEDAMHKPGL---WHHQTEVSGTQTTAQLKLSPYVNYSFRV 705



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 52/224 (23%), Positives = 87/224 (38%), Gaps = 18/224 (8%)

Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG-QSIEASSRFTSIFRFGYISLDMLSL 701
           L+ +T   G  +    R  P+G P   I W+ N  Q +  S R +          ++L  
Sbjct: 146 LEPITLQSGQSLVLPCR-PPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 204

Query: 702 NIQDSGEYTCRA-VSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQE 760
           + ++  +Y C A  + T   + K  + V   +  E      +T+     L D   Y  + 
Sbjct: 205 DTRE--DYICYARFNHTQTIQQKQPISVKVISVDELN----DTIA--ANLSDTEFYGAKS 256

Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           S E      P F+ P  +    +E R      +      PT  + W K+   +  +  + 
Sbjct: 257 SRERP----PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 312

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
             F     +L I+H+   D+G+Y   A N LG    T S+RV A
Sbjct: 313 KNFE---KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 353



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 9/114 (7%)

Query: 637 PQFIVPLKSVTAME-GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           P +IV       ++ G  + FE +++     ++ + WLK+ + + +  RFT         
Sbjct: 539 PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDH 594

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV----TPRATIERTSQHPETLQ 745
           L +  ++  DSG YTC A +        AVL V     P   +E T Q  +++Q
Sbjct: 595 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQ 648



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P +I +      +  G    +EC+++     ++ V W  + + L S  R+    D     
Sbjct: 539  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH---- 594

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            L +  V  +DSG YTC A   L    +S  L+V
Sbjct: 595  LVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 627



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + PR L P     +++  + A  +      S L  T+EW+   K       I   H+ 
Sbjct: 444  LAEPPRILTPANTLYQVIANRPALLDCAFFG-SPLP-TIEWFKGAKGSALHEDIYVLHEN 501

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            G   L+I   + + +G YT VARN  G A+    + ++
Sbjct: 502  G--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 537



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q G    F+C++      +L V W ++ + +    R T   D     + ++ V D+D G
Sbjct: 551  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVADVSDDDSG 606

Query: 2448 VYMCRASNLL 2457
             Y C A+  L
Sbjct: 607  TYTCVANTTL 616



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 4/79 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G+ V  EC+++     ++ V W  + + + +  RF      D   L +  V  +DSG YT
Sbjct: 554  GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 609

Query: 1385 CQATNQLGEAVTSCALRVI 1403
            C A   L     S  L V+
Sbjct: 610  CVANTTLDSVSASAVLSVV 628



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 26/122 (21%), Positives = 56/122 (45%), Gaps = 7/122 (5%)

Query: 251 QISTEIDRSLGPVSPPKIAQK-PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
           Q+ + ++  L  V PP I Q+ P++  +    +   Q +  G P P  +W +NG    + 
Sbjct: 25  QMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTH-FDI 83

Query: 310 NKHEIITTHNHT---TLRVRNTQKSDS--GHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           +K  ++T    T    + + +  K+++  G Y   A N  G  V++  +   S +  + +
Sbjct: 84  DKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTK 143

Query: 365 DQ 366
           ++
Sbjct: 144 EK 145



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 4/97 (4%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            E  +P      P   ++   S   FEC++   +  S+ V W  + + L +  R     D 
Sbjct: 535  EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 594

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                L +  V   D+G YTC A       + S  L V
Sbjct: 595  ----LVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 627



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P +      Y  +  G  V  E +V+     +L + W K+   L +  R     D     
Sbjct: 539  PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH---- 594

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L +  + +DDSG YTC A   L    ++A + + D
Sbjct: 595  LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVD 629



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 3/67 (4%)

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           G  + L   A G PTP I W K+   +   P+ R        TL I     +D+  YQC 
Sbjct: 279 GNVLSLECIAEGLPTPIIYWAKEDGML---PKNRTVYKNFEKTLQIIHVSEADSGNYQCI 335

Query: 565 AQNVAGS 571
           A+N  G+
Sbjct: 336 AKNALGA 342



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%)

Query: 1706 VITQAPVFTMPMKDI-RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            V+ + P    P   + +V  N+ A  +      G P   +EW +          +  +H+
Sbjct: 443  VLAEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHE 500

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
             G   L +     + +GTYTC A N+LG A
Sbjct: 501  NG--TLEIPVAQKDSTGTYTCVARNKLGMA 528


>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
          Length = 1192

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 100/437 (22%), Positives = 175/437 (40%), Gaps = 52/437 (11%)

Query: 4387 TTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQAR---FEVEFDGEPLPLIK 4443
            T  I+ K     +V+       +PP F          E  +      E   +G P P+I 
Sbjct: 225  TQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIY 284

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            W +E+  +  +    ++    K++ II  V   DS  +  +A+N  G    + ++ V+  
Sbjct: 285  WAKEDGMLPKNRT--VYKNFEKTLQIIH-VSEADSGNYQCIAKNALGAIHHTISVRVK-- 339

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNK 4561
                      P +    QN+ ++ G+   L  +  G     + WL NG  ++  PD  ++
Sbjct: 340  --------AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSR 391

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             ++ D   T++      + S  Y+C A N  G    +A   V++ A              
Sbjct: 392  KIDGD---TIIFSNVQERSSAVYQCNASNEYGYLLANA--FVNVLAE------------- 433

Query: 4622 PPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            PP I+ P     +++A   A+   C   G PLPT++W+KG K    + +  +    +  T
Sbjct: 434  PPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAK--GSALHEDIYVLHENGT 490

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739
            L I  A  +  G Y CVA N  G       L++         P        VV  G    
Sbjct: 491  LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYA-----VVQRGSMVS 545

Query: 4740 FKTQI--TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
            F+ ++     +  T+ WL++   +P    F +    +   L++ +  ++D+GT+TC A T
Sbjct: 546  FECKVKHDHTLSLTVLWLKDNRELPSDERFTV----DKDHLVVADVSDDDSGTYTCVANT 601

Query: 4798 AAGQVETSAKLVVKSKT 4814
                V  SA L V + T
Sbjct: 602  TLDSVSASAVLSVVAPT 618



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 88/408 (21%), Positives = 162/408 (39%), Gaps = 35/408 (8%)

Query: 4409 KPPIFTKKMQPCRVFE-HEQARFEVEFDGEPLPLIKWYRE--NFPIKNSPDFQIHTFS-T 4464
            +PP  T++     + +  E    + E  G+P P   W R   +F I   P   +   + T
Sbjct: 44   QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103

Query: 4465 KSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA-QN 4522
              I I+ +   E    V+   A N  G A  S N+VV   R         P +T    + 
Sbjct: 104  LIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVRPSRS--------PLWTKEKLEP 154

Query: 4523 VNVTSGQLVRLDTKVT-GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            + + SGQ + L  +   G  P  ++W+ N  +  P  +++ + +     L      P+D+
Sbjct: 155  ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLP--QSERVSQGLNGDLYFSNVLPEDT 212

Query: 4582 GK-YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
             + Y C A  +  +     +  +S+     K   +       PE     K+++   G  +
Sbjct: 213  REDYICYARFNHTQT-IQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEEL--RGNVL 269

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
               C   G P P + W K D ++  ++    +    E TL+I      D G+Y+C+A N+
Sbjct: 270  SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF---EKTLQIIHVSEADSGNYQCIAKNA 326

Query: 4701 AGRV--TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
             G +  T++ ++K            +T  +++V+  G+      +     KP I WL  G
Sbjct: 327  LGAIHHTISVRVKAAP-------YWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 379

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
              I   PD     + +   ++  N  E  +  + C A+   G +  +A
Sbjct: 380  VPIEIAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 426



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 64/238 (26%), Positives = 100/238 (42%), Gaps = 17/238 (7%)

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA---PQFV 395
           +++  NG +  S  L  E   E Y+   R  +    QQ++      IS K+     P F+
Sbjct: 194 VSQGLNGDLYFSNVLP-EDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFL 252

Query: 396 KV---CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
                  +++   G +   +C   G P P + W   D  +  +      V ++    L I
Sbjct: 253 TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRT----VYKNFEKTLQI 308

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
            +V+ +DSG   C+A+N  G  A    ++V  K    AP ++     L +  GE   L  
Sbjct: 309 IHVSEADSGNYQCIAKNALG--AIHHTISVRVK---AAPYWITAPQNLVLSPGEDGTLIC 363

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           RA G P PRI+W  +GVPI   P+       G  T+     +   +A YQC A N  G
Sbjct: 364 RANGNPKPRISWLTNGVPIEIAPDDPSRKIDG-DTIIFSNVQERSSAVYQCNASNEYG 420



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 53/200 (26%), Positives = 84/200 (42%), Gaps = 16/200 (8%)

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR---DDYNHK 439
           I +  KA AP ++   Q+  ++ G+     CR  G P P ++W  N   I    DD + K
Sbjct: 334 ISVRVKA-APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 392

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           I         ++ +NV    S V  C A N+ G       +NV+ +     P+ +   +T
Sbjct: 393 I-----DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP----PRILTPANT 443

Query: 500 L-NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           L  V    P +L+    G+P P I W K       + ++ +  + G  TL+IP A+    
Sbjct: 444 LYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDST 501

Query: 559 AWYQCTAQNVAGSTATRARL 578
             Y C A+N  G       L
Sbjct: 502 GTYTCVARNKLGMAKNEVHL 521



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 72/318 (22%), Positives = 132/318 (41%), Gaps = 26/318 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSIL 4468
            P I T      +V  +  A  +  F G PLP I+W++       +   + +H   T  I 
Sbjct: 435  PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIP 494

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            + ++   + +  +  VA N+ G AK   +L +++        +  P + +      V  G
Sbjct: 495  VAQK---DSTGTYTCVARNKLGMAKNEVHLEIKD----ATWIVKQPEYAV------VQRG 541

Query: 4529 QLVRLDTKV--TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             +V  + KV    T  + V WLK+ +++  D R  + ++D    L++ +    DSG Y C
Sbjct: 542  SMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV-DKD---HLVVADVSDDDSGTYTC 597

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VA N+  ++   A  V+S+ A    P P     N PP  +E L D++    Q        
Sbjct: 598  VA-NTTLDS-VSASAVLSVVAPTPTPAPVYDVPN-PPFDLE-LTDQLDKSVQLSWTPGDD 653

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR--V 4704
               P+        D + KP  +   +  +   T    +  P     ++ +A NS G+   
Sbjct: 654  NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 713

Query: 4705 TVAAKLKVTQPDQADNLP 4722
            + A++  +T+  + D  P
Sbjct: 714  SEASEQYLTKASEPDKNP 731



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 47/181 (25%), Positives = 72/181 (39%), Gaps = 16/181 (8%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP   T    +  +   + A  + +    G     IEWF   K       I  ++  G  
Sbjct: 434  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 489

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEGLKDGQ 3165
             LEI   +   +GTY+C A NK G A+  V LE  D +   ++P +         ++ G 
Sbjct: 490  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAV-------VQRGS 542

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
               FEC V       + + W  + + +    R  TV     VV D++   + DSG Y C 
Sbjct: 543  MVSFECKVKHDHTLSLTVLWLKDNRELPSDERF-TVDKDHLVVADVS---DDDSGTYTCV 598

Query: 3226 A 3226
            A
Sbjct: 599  A 599



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 16/197 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RPP F T   +  +  E +        I  G  + +I W      +  +   RTVY    
Sbjct: 247  RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN---RTVYKNFE 303

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              L+I+     DSG Y C A N  G     ISV+++         P + T  QN+  L  
Sbjct: 304  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA-------PYWITAPQNLV-LSP 355

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+     C      +P  +I W  NG P+  +    +    G  ++  +  Q   S  Y 
Sbjct: 356  GEDGTLICRA--NGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQ 412

Query: 3224 CRAYNKYGEDFTRATIN 3240
            C A N+YG     A +N
Sbjct: 413  CNASNEYGYLLANAFVN 429



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V + G  + FEC V+     +L + W  +N+ LPS  R+    D   V+ D++   ++DS
Sbjct: 537  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVS---DDDS 592

Query: 2844 GIYTCKATNSKGSATTSGSL 2863
            G YTC A  +  S + S  L
Sbjct: 593  GTYTCVANTTLDSVSASAVL 612



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 67/305 (21%), Positives = 110/305 (36%), Gaps = 21/305 (6%)

Query: 61  ITAGRPGEPSPPIF---EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNK 117
           + + +     PP F   E    N    +G     E    G PTP++ W ++   L + N+
Sbjct: 238 VISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPK-NR 296

Query: 118 YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXX 177
              +  E+T    L I  +   D G Y C A+N  G    ++ ++ +             
Sbjct: 297 TVYKNFEKT----LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLV 352

Query: 178 XYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFR 237
                  T+  +A G        S  T  V      D  S    K+D  +  +   V  R
Sbjct: 353 LSPGEDGTLICRANGNP--KPRISWLTNGVPIEIAPDDPSR---KIDG-DTIIFSNVQER 406

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGAD--AQFQVQLSGNPRP 295
            S   +    ++       +  +  ++ P     P N+  Q  A+  A       G+P P
Sbjct: 407 SSAVYQCNASNEYGYLL-ANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLP 465

Query: 296 RVTWFKNGQRLINSNKHE-IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLA 354
            + WFK  +    S  HE I   H + TL +   QK  +G YT +A N  G      +L 
Sbjct: 466 TIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 522

Query: 355 VESPT 359
           ++  T
Sbjct: 523 IKDAT 527



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP +  A  N+    G +  L CR    G+   R+ W  NG PI+      P+ +
Sbjct: 336  VRVKAAPYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPD-DPSRK 392

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
             D   +   +V    S VY C A+N+ G  + +  + V+A+   IL
Sbjct: 393  IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRIL 438



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            + +  P +++ P  + +  GE     CR  G+PKPR+ WL NG
Sbjct: 337  RVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 379



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 7/107 (6%)

Query: 1177 PVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            P F+ P  N     E  G  + LEC  E  G PT  + W      +    + +T Y    
Sbjct: 249  PTFLTPEGNASNKEELRGNVLSLECIAE--GLPTPIIYWAKEDGMLP---KNRTVYKNFE 303

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281
              L IIH + AD+G Y   A N LG+ H +  VRV      +T  QN
Sbjct: 304  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN 350



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980
            ++ G    FE +++     +L V WLKD R + +  R T   +     L +  V+  D+G
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 593

Query: 981  HYTCRAYNAIGQATTSANLTIV 1002
             YTC A   +   + SA L++V
Sbjct: 594  TYTCVANTTLDSVSASAVLSVV 615



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)

Query: 2356 LESAEPFKRPEIPEPVTRQRP-VFTQPLQNIDNIQE--GQTAHFDCRLIPVGDPTLKVEW 2412
            ++  +P     I    +R+RP  F  P  N  N +E  G     +C  I  G PT  + W
Sbjct: 228  IQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLEC--IAEGLPTPIIYW 285

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             + + ++  +  + K  +    ++ I HV + D G Y C A N LG
Sbjct: 286  AKEDGMLPKNRTVYKNFE---KTLQIIHVSEADSGNYQCIAKNALG 328



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            AEPP+ +T    + +++  + A  +        P   +EWF   K           H+ G
Sbjct: 432  AEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG 489

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
               L+I    ++++G Y CVA NKLG    + +L+
Sbjct: 490  T--LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 522



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            +  G    FE +V+    L++TV W  + +++ S  R     D     L +A V  +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 593

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
             YT VA         SA ++V
Sbjct: 594  TYTCVANTTLDSVSASAVLSV 614



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/159 (25%), Positives = 67/159 (42%), Gaps = 12/159 (7%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP   T  + L  +  N  A  +C           +EWF   K       +  +++ G  
Sbjct: 434  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 489

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ-- 3673
             LEI    +   G YTC A N+ G A     L++K    I+ +P+     +    S +  
Sbjct: 490  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSFECK 549

Query: 3674 -KLEETLHKREEITIED--EKPNPPRFTVEIKDNIDVPE 3709
             K + TL     + ++D  E P+  RFTV+ KD++ V +
Sbjct: 550  VKHDHTL-SLTVLWLKDNRELPSDERFTVD-KDHLVVAD 586



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 4/86 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PPR          V    P   DC     G P   I+WF   +  A    ++ L++ G  
Sbjct: 434  PPRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWFKGAKGSALHEDIYVLHENG-- 489

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSA 3779
             L+I        G YTC A NK G A
Sbjct: 490  TLEIPVAQKDSTGTYTCVARNKLGMA 515



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 3/102 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P + T P +L+LS        CR     +   R+ W  NG P+       +    G  I+
Sbjct: 342  PYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 399

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
                V +R + +Y C A+N +G    +  + V      IL P
Sbjct: 400  -FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 440



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 43/170 (25%), Positives = 63/170 (37%), Gaps = 16/170 (9%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           DC   G P P + WF   +  +    H+ +     N  L I       +G  TCVARNK 
Sbjct: 456 DCAFFGSPLPTIEWF---KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 512

Query: 472 GETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTPRIT--WQKDG 528
           G    +  L + +   +V  P++        V+ G  V    +     T  +T  W KD 
Sbjct: 513 GMAKNEVHLEIKDATWIVKQPEYAV------VQRGSMVSFECKVKHDHTLSLTVLWLKDN 566

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +P+ E R   D     L +      D+  Y C A     S +  A L
Sbjct: 567 RE-LPSDE-RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVL 612



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            IEWFK          +    + G  TL I   + D +G YTC A N LG A +   ++I+
Sbjct: 467  IEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 524

Query: 2736 DRHWLL 2741
            D  W++
Sbjct: 525  DATWIV 530



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           P I +Q  K+       N   + + +G P P  SWTR            +     TG + 
Sbjct: 46  PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 105

Query: 131 LLIKQIGPGD--EGEYTCTARNQYGEAIC-SVYIQP 163
           + I   G  +  EG Y CTARN+ G A+  ++ ++P
Sbjct: 106 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRP 141



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 8/100 (8%)

Query: 3829 PPKFIT-QIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            PP F+T +  +   EE  G  +  EC  E    P   I W +   +LP     RTVY   
Sbjct: 248  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPI--IYWAKEDGMLPKN---RTVYKNF 302

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              +L I++V   DSG Y C A N  G      ++  K  P
Sbjct: 303  EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 342



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G+PK R+ WL NGVPIE +    +    G   +    V    S  Y C A NE G
Sbjct: 367  GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYG 420



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + PR +T  N   ++   + A  +C     P P   +EW+   K           ++ G 
Sbjct: 433  EPPRILTPANTLYQVIANRPALLDCAFFGSPLPT--IEWFKGAKGSALHEDIYVLHENG- 489

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
              L+I     + +G YTC A N LG A + + L ++    I++  ++
Sbjct: 490  -TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEY 535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-YRTTHDFGYV 2167
            P  LT   +L  +     A  +C       P  TI+WF  G K  A H      H+ G  
Sbjct: 435  PRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWF-KGAKGSALHEDIYVLHENG-- 489

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L+I     + +GTY C A NKLG A N   L++
Sbjct: 490  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI 523



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1589 IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSG 1648
            ++ G    FE ++      +L V W  +N+ L S  RFT   +   V  D+     +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSD---DDSG 593

Query: 1649 TYTCRAINALGEAVTSGIAIV 1669
            TYTC A   L     S +  V
Sbjct: 594  TYTCVANTTLDSVSASAVLSV 614



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            ++ G    FEC+V+  +   LT+ W  + +++ +  R+    D   VA D+     +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DV---SDDDSG 593

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
            TY C A   L     +  L V
Sbjct: 594  TYTCVANTTLDSVSASAVLSV 614



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G  V FECK++     +L V W K+ + +    RF    D   VA D+ D   +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVSD---DDSG 593

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTT 1540
             YTC A   + +   S  L+  + T
Sbjct: 594  TYTCVANTTLDSVSASAVLSVVAPT 618



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G+ V  EC+++     ++ V W  + + + +  RF      D   L +  V  +DSG YT
Sbjct: 541  GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 596

Query: 1385 CQATNQLGEAVTSCALRVIA 1404
            C A   L     S  L V+A
Sbjct: 597  CVANTTLDSVSASAVLSVVA 616



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 3/104 (2%)

Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           S +    + P F+ P  +    +E R      +      PT  + W K+   +  +  + 
Sbjct: 240 SAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 299

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
             F     +L I+H+   D+G+Y   A N LG    T S+RV A
Sbjct: 300 KNFE---KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 340



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            +  G    +EC+++     ++ V W  + + L S  R+    D     L +  V  +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 593

Query: 1916 EYTCKAINNLGQAVSSIRLNV 1936
             YTC A   L    +S  L+V
Sbjct: 594  TYTCVANTTLDSVSASAVLSV 614



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)

Query: 406 GKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV-V 463
           G+     CR   G P P + W  N  Q R   + +  V++  N  L  +NV   D+    
Sbjct: 160 GQSLVLPCRPPIGLPPPIIFWMDNSFQ-RLPQSER--VSQGLNGDLYFSNVLPEDTREDY 216

Query: 464 TCVARNKSGETAFQCR---LNVI--EKEQVVAPKFVERFSTLNVRE---GEPVVLNARAV 515
            C AR    +T  Q +   + VI  +  +   P F+      + +E   G  + L   A 
Sbjct: 217 ICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE 276

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
           G PTP I W K+   +   P+ R        TL I     +D+  YQC A+N  G+
Sbjct: 277 GLPTPIIYWAKEDGML---PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA 329



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + PR L P     +++  + A  +      S L  T+EW+   K       I   H+ 
Sbjct: 431  LAEPPRILTPANTLYQVIANRPALLDCAFFG-SPLP-TIEWFKGAKGSALHEDIYVLHEN 488

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            G   L+I   + + +G YT VARN  G A+    + ++
Sbjct: 489  G--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 524



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDIL 3892
            + Q +   V+    V FEC+V+      L + W ++ + LPS  R+    D     L + 
Sbjct: 530  VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVA 585

Query: 3893 YVYAEDSGEYICRA 3906
             V  +DSG Y C A
Sbjct: 586  DVSDDDSGTYTCVA 599



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q G    F+C++      +L V W ++ + +    R T   D     + ++ V D+D G
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVADVSDDDSG 593

Query: 2448 VYMCRASNLL 2457
             Y C A+  L
Sbjct: 594  TYTCVANTTL 603



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 10/118 (8%)

Query: 378 ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT--WFINDRQIRDD 435
           + E  +EI +   A   VK  +   V  G M  F+C+V       +T  W  ++R++  D
Sbjct: 516 KNEVHLEIKD---ATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSD 572

Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
              +  V++  +H L++ +V+  DSG  TCVA       +    L+V+      AP +
Sbjct: 573 --ERFTVDK--DH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVY 625



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 651 GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYT 710
           G  + FE +++     ++ + WLK+ + + +  RFT         L +  ++  DSG YT
Sbjct: 541 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 596

Query: 711 CRAVSATGVAETKAVLHV---TPR-ATIERTSQHPETLQYIQQLE 751
           C A +        AVL V   TP  A +      P  L+   QL+
Sbjct: 597 CVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 641



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%)

Query: 1706 VITQAPVFTMPMKDI-RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            V+ + P    P   + +V  N+ A  +      G P   +EW +          +  +H+
Sbjct: 430  VLAEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHE 487

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
             G   L +     + +GTYTC A N+LG A
Sbjct: 488  NG--TLEIPVAQKDSTGTYTCVARNKLGMA 515



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/105 (23%), Positives = 45/105 (42%), Gaps = 6/105 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK-VEWFKNGQPVTIGHRFRPIHDFGYV 1502
            PR +T   ++  VI  +    +C       S L  +EWFK  +   +      +H+ G +
Sbjct: 435  PRILTPANTLYQVIANRPALLDCAF---FGSPLPTIEWFKGAKGSALHEDIYVLHENGTL 491

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
             + +     + +G YTC A N +G  +    L  +  T IV+  +
Sbjct: 492  EIPVAQ--KDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPE 534



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 7/110 (6%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVE-GQVLHLEGQVEPKNDPDLKIEWYFNG 2951
            AR   G   +    E     WI+    E+ +V+ G ++  E +V+  +   L + W  + 
Sbjct: 508  ARNKLGMAKNEVHLEIKDATWIVK-QPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDN 566

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + L    RF +  D     L + DV + DSG YTC A N   ++ ++S V
Sbjct: 567  RELPSDERFTVDKDH----LVVADVSDDDSGTYTCVA-NTTLDSVSASAV 611


>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
          Length = 1180

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 100/437 (22%), Positives = 175/437 (40%), Gaps = 52/437 (11%)

Query: 4387 TTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQAR---FEVEFDGEPLPLIK 4443
            T  I+ K     +V+       +PP F          E  +      E   +G P P+I 
Sbjct: 225  TQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIY 284

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            W +E+  +  +    ++    K++ II  V   DS  +  +A+N  G    + ++ V+  
Sbjct: 285  WAKEDGMLPKNRT--VYKNFEKTLQIIH-VSEADSGNYQCIAKNALGAIHHTISVRVK-- 339

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNK 4561
                      P +    QN+ ++ G+   L  +  G     + WL NG  ++  PD  ++
Sbjct: 340  --------AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSR 391

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             ++ D   T++      + S  Y+C A N  G    +A   V++ A              
Sbjct: 392  KIDGD---TIIFSNVQERSSAVYQCNASNEYGYLLANA--FVNVLAE------------- 433

Query: 4622 PPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            PP I+ P     +++A   A+   C   G PLPT++W+KG K    + +  +    +  T
Sbjct: 434  PPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAK--GSALHEDIYVLHENGT 490

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739
            L I  A  +  G Y CVA N  G       L++         P        VV  G    
Sbjct: 491  LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYA-----VVQRGSMVS 545

Query: 4740 FKTQI--TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
            F+ ++     +  T+ WL++   +P    F +    +   L++ +  ++D+GT+TC A T
Sbjct: 546  FECKVKHDHTLSLTVLWLKDNRELPSDERFTV----DKDHLVVADVSDDDSGTYTCVANT 601

Query: 4798 AAGQVETSAKLVVKSKT 4814
                V  SA L V + T
Sbjct: 602  TLDSVSASAVLSVVAPT 618



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 88/408 (21%), Positives = 162/408 (39%), Gaps = 35/408 (8%)

Query: 4409 KPPIFTKKMQPCRVFE-HEQARFEVEFDGEPLPLIKWYRE--NFPIKNSPDFQIHTFS-T 4464
            +PP  T++     + +  E    + E  G+P P   W R   +F I   P   +   + T
Sbjct: 44   QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103

Query: 4465 KSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA-QN 4522
              I I+ +   E    V+   A N  G A  S N+VV   R         P +T    + 
Sbjct: 104  LIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVRPSRS--------PLWTKEKLEP 154

Query: 4523 VNVTSGQLVRLDTKVT-GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            + + SGQ + L  +   G  P  ++W+ N  +  P  +++ + +     L      P+D+
Sbjct: 155  ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLP--QSERVSQGLNGDLYFSNVLPEDT 212

Query: 4582 GK-YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
             + Y C A  +  +     +  +S+     K   +       PE     K+++   G  +
Sbjct: 213  REDYICYARFNHTQT-IQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEEL--RGNVL 269

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
               C   G P P + W K D ++  ++    +    E TL+I      D G+Y+C+A N+
Sbjct: 270  SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF---EKTLQIIHVSEADSGNYQCIAKNA 326

Query: 4701 AGRV--TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
             G +  T++ ++K            +T  +++V+  G+      +     KP I WL  G
Sbjct: 327  LGAIHHTISVRVKAAP-------YWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 379

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
              I   PD     + +   ++  N  E  +  + C A+   G +  +A
Sbjct: 380  VPIEIAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 426



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 64/238 (26%), Positives = 100/238 (42%), Gaps = 17/238 (7%)

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA---PQFV 395
           +++  NG +  S  L  E   E Y+   R  +    QQ++      IS K+     P F+
Sbjct: 194 VSQGLNGDLYFSNVLP-EDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFL 252

Query: 396 KV---CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
                  +++   G +   +C   G P P + W   D  +  +      V ++    L I
Sbjct: 253 TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRT----VYKNFEKTLQI 308

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
            +V+ +DSG   C+A+N  G  A    ++V  K    AP ++     L +  GE   L  
Sbjct: 309 IHVSEADSGNYQCIAKNALG--AIHHTISVRVK---AAPYWITAPQNLVLSPGEDGTLIC 363

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           RA G P PRI+W  +GVPI   P+       G  T+     +   +A YQC A N  G
Sbjct: 364 RANGNPKPRISWLTNGVPIEIAPDDPSRKIDG-DTIIFSNVQERSSAVYQCNASNEYG 420



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 53/200 (26%), Positives = 84/200 (42%), Gaps = 16/200 (8%)

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR---DDYNHK 439
           I +  KA AP ++   Q+  ++ G+     CR  G P P ++W  N   I    DD + K
Sbjct: 334 ISVRVKA-APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 392

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           I         ++ +NV    S V  C A N+ G       +NV+ +     P+ +   +T
Sbjct: 393 I-----DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP----PRILTPANT 443

Query: 500 L-NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           L  V    P +L+    G+P P I W K       + ++ +  + G  TL+IP A+    
Sbjct: 444 LYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDST 501

Query: 559 AWYQCTAQNVAGSTATRARL 578
             Y C A+N  G       L
Sbjct: 502 GTYTCVARNKLGMAKNEVHL 521



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 72/318 (22%), Positives = 132/318 (41%), Gaps = 26/318 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSIL 4468
            P I T      +V  +  A  +  F G PLP I+W++       +   + +H   T  I 
Sbjct: 435  PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIP 494

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            + ++   + +  +  VA N+ G AK   +L +++        +  P + +      V  G
Sbjct: 495  VAQK---DSTGTYTCVARNKLGMAKNEVHLEIKD----ATWIVKQPEYAV------VQRG 541

Query: 4529 QLVRLDTKV--TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             +V  + KV    T  + V WLK+ +++  D R  + ++D    L++ +    DSG Y C
Sbjct: 542  SMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV-DKD---HLVVADVSDDDSGTYTC 597

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VA N+  ++   A  V+S+ A    P P     N PP  +E L D++    Q        
Sbjct: 598  VA-NTTLDS-VSASAVLSVVAPTPTPAPVYDVPN-PPFDLE-LTDQLDKSVQLSWTPGDD 653

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR--V 4704
               P+        D + KP  +   +  +   T    +  P     ++ +A NS G+   
Sbjct: 654  NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 713

Query: 4705 TVAAKLKVTQPDQADNLP 4722
            + A++  +T+  + D  P
Sbjct: 714  SEASEQYLTKASEPDKNP 731



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 47/181 (25%), Positives = 72/181 (39%), Gaps = 16/181 (8%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP   T    +  +   + A  + +    G     IEWF   K       I  ++  G  
Sbjct: 434  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 489

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEGLKDGQ 3165
             LEI   +   +GTY+C A NK G A+  V LE  D +   ++P +         ++ G 
Sbjct: 490  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAV-------VQRGS 542

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
               FEC V       + + W  + + +    R  TV     VV D++   + DSG Y C 
Sbjct: 543  MVSFECKVKHDHTLSLTVLWLKDNRELPSDERF-TVDKDHLVVADVS---DDDSGTYTCV 598

Query: 3226 A 3226
            A
Sbjct: 599  A 599



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 16/197 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RPP F T   +  +  E +        I  G  + +I W      +  +   RTVY    
Sbjct: 247  RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN---RTVYKNFE 303

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              L+I+     DSG Y C A N  G     ISV+++         P + T  QN+  L  
Sbjct: 304  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA-------PYWITAPQNLV-LSP 355

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+     C      +P  +I W  NG P+  +    +    G  ++  +  Q   S  Y 
Sbjct: 356  GEDGTLICRA--NGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQ 412

Query: 3224 CRAYNKYGEDFTRATIN 3240
            C A N+YG     A +N
Sbjct: 413  CNASNEYGYLLANAFVN 429



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V + G  + FEC V+     +L + W  +N+ LPS  R+    D   V+ D++   ++DS
Sbjct: 537  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVS---DDDS 592

Query: 2844 GIYTCKATNSKGSATTSGSL 2863
            G YTC A  +  S + S  L
Sbjct: 593  GTYTCVANTTLDSVSASAVL 612



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 67/305 (21%), Positives = 110/305 (36%), Gaps = 21/305 (6%)

Query: 61  ITAGRPGEPSPPIF---EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNK 117
           + + +     PP F   E    N    +G     E    G PTP++ W ++   L + N+
Sbjct: 238 VISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPK-NR 296

Query: 118 YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXX 177
              +  E+T    L I  +   D G Y C A+N  G    ++ ++ +             
Sbjct: 297 TVYKNFEKT----LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLV 352

Query: 178 XYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFR 237
                  T+  +A G        S  T  V      D  S    K+D  +  +   V  R
Sbjct: 353 LSPGEDGTLICRANGNP--KPRISWLTNGVPIEIAPDDPSR---KIDG-DTIIFSNVQER 406

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGAD--AQFQVQLSGNPRP 295
            S   +    ++       +  +  ++ P     P N+  Q  A+  A       G+P P
Sbjct: 407 SSAVYQCNASNEYGYLL-ANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLP 465

Query: 296 RVTWFKNGQRLINSNKHE-IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLA 354
            + WFK  +    S  HE I   H + TL +   QK  +G YT +A N  G      +L 
Sbjct: 466 TIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 522

Query: 355 VESPT 359
           ++  T
Sbjct: 523 IKDAT 527



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP +  A  N+    G +  L CR    G+   R+ W  NG PI+      P+ +
Sbjct: 336  VRVKAAPYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPD-DPSRK 392

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
             D   +   +V    S VY C A+N+ G  + +  + V+A+   IL
Sbjct: 393  IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRIL 438



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            + +  P +++ P  + +  GE     CR  G+PKPR+ WL NG
Sbjct: 337  RVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 379



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 7/107 (6%)

Query: 1177 PVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            P F+ P  N     E  G  + LEC  E  G PT  + W      +    + +T Y    
Sbjct: 249  PTFLTPEGNASNKEELRGNVLSLECIAE--GLPTPIIYWAKEDGMLP---KNRTVYKNFE 303

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281
              L IIH + AD+G Y   A N LG+ H +  VRV      +T  QN
Sbjct: 304  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN 350



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980
            ++ G    FE +++     +L V WLKD R + +  R T   +     L +  V+  D+G
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 593

Query: 981  HYTCRAYNAIGQATTSANLTIV 1002
             YTC A   +   + SA L++V
Sbjct: 594  TYTCVANTTLDSVSASAVLSVV 615



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)

Query: 2356 LESAEPFKRPEIPEPVTRQRP-VFTQPLQNIDNIQE--GQTAHFDCRLIPVGDPTLKVEW 2412
            ++  +P     I    +R+RP  F  P  N  N +E  G     +C  I  G PT  + W
Sbjct: 228  IQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLEC--IAEGLPTPIIYW 285

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             + + ++  +  + K  +    ++ I HV + D G Y C A N LG
Sbjct: 286  AKEDGMLPKNRTVYKNFE---KTLQIIHVSEADSGNYQCIAKNALG 328



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            AEPP+ +T    + +++  + A  +        P   +EWF   K           H+ G
Sbjct: 432  AEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG 489

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
               L+I    ++++G Y CVA NKLG    + +L+
Sbjct: 490  T--LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 522



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            +  G    FE +V+    L++TV W  + +++ S  R     D     L +A V  +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 593

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
             YT VA         SA ++V
Sbjct: 594  TYTCVANTTLDSVSASAVLSV 614



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/159 (25%), Positives = 67/159 (42%), Gaps = 12/159 (7%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP   T  + L  +  N  A  +C           +EWF   K       +  +++ G  
Sbjct: 434  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 489

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ-- 3673
             LEI    +   G YTC A N+ G A     L++K    I+ +P+     +    S +  
Sbjct: 490  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSFECK 549

Query: 3674 -KLEETLHKREEITIED--EKPNPPRFTVEIKDNIDVPE 3709
             K + TL     + ++D  E P+  RFTV+ KD++ V +
Sbjct: 550  VKHDHTL-SLTVLWLKDNRELPSDERFTVD-KDHLVVAD 586



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 4/86 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PPR          V    P   DC     G P   I+WF   +  A    ++ L++ G  
Sbjct: 434  PPRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWFKGAKGSALHEDIYVLHENG-- 489

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSA 3779
             L+I        G YTC A NK G A
Sbjct: 490  TLEIPVAQKDSTGTYTCVARNKLGMA 515



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 3/102 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P + T P +L+LS        CR     +   R+ W  NG P+       +    G  I+
Sbjct: 342  PYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 399

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
                V +R + +Y C A+N +G    +  + V      IL P
Sbjct: 400  -FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 440



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 43/170 (25%), Positives = 63/170 (37%), Gaps = 16/170 (9%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           DC   G P P + WF   +  +    H+ +     N  L I       +G  TCVARNK 
Sbjct: 456 DCAFFGSPLPTIEWF---KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 512

Query: 472 GETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTPRIT--WQKDG 528
           G    +  L + +   +V  P++        V+ G  V    +     T  +T  W KD 
Sbjct: 513 GMAKNEVHLEIKDATWIVKQPEYAV------VQRGSMVSFECKVKHDHTLSLTVLWLKDN 566

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +P+ E R   D     L +      D+  Y C A     S +  A L
Sbjct: 567 RE-LPSDE-RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVL 612



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            IEWFK          +    + G  TL I   + D +G YTC A N LG A +   ++I+
Sbjct: 467  IEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 524

Query: 2736 DRHWLL 2741
            D  W++
Sbjct: 525  DATWIV 530



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           P I +Q  K+       N   + + +G P P  SWTR            +     TG + 
Sbjct: 46  PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 105

Query: 131 LLIKQIGPGD--EGEYTCTARNQYGEAIC-SVYIQP 163
           + I   G  +  EG Y CTARN+ G A+  ++ ++P
Sbjct: 106 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRP 141



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 8/100 (8%)

Query: 3829 PPKFIT-QIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            PP F+T +  +   EE  G  +  EC  E    P   I W +   +LP     RTVY   
Sbjct: 248  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPI--IYWAKEDGMLPKN---RTVYKNF 302

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              +L I++V   DSG Y C A N  G      ++  K  P
Sbjct: 303  EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 342



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G+PK R+ WL NGVPIE +    +    G   +    V    S  Y C A NE G
Sbjct: 367  GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYG 420



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + PR +T  N   ++   + A  +C     P P   +EW+   K           ++ G 
Sbjct: 433  EPPRILTPANTLYQVIANRPALLDCAFFGSPLPT--IEWFKGAKGSALHEDIYVLHENG- 489

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
              L+I     + +G YTC A N LG A + + L ++    I++  ++
Sbjct: 490  -TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEY 535



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-YRTTHDFGYV 2167
            P  LT   +L  +     A  +C       P  TI+WF  G K  A H      H+ G  
Sbjct: 435  PRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWF-KGAKGSALHEDIYVLHENG-- 489

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L+I     + +GTY C A NKLG A N   L++
Sbjct: 490  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI 523



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1589 IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSG 1648
            ++ G    FE ++      +L V W  +N+ L S  RFT   +   V  D+     +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSD---DDSG 593

Query: 1649 TYTCRAINALGEAVTSGIAIV 1669
            TYTC A   L     S +  V
Sbjct: 594  TYTCVANTTLDSVSASAVLSV 614



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            ++ G    FEC+V+  +   LT+ W  + +++ +  R+    D   VA D+     +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DV---SDDDSG 593

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
            TY C A   L     +  L V
Sbjct: 594  TYTCVANTTLDSVSASAVLSV 614



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G  V FECK++     +L V W K+ + +    RF    D   VA D+ D   +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVSD---DDSG 593

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTT 1540
             YTC A   + +   S  L+  + T
Sbjct: 594  TYTCVANTTLDSVSASAVLSVVAPT 618



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G+ V  EC+++     ++ V W  + + + +  RF      D   L +  V  +DSG YT
Sbjct: 541  GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 596

Query: 1385 CQATNQLGEAVTSCALRVIA 1404
            C A   L     S  L V+A
Sbjct: 597  CVANTTLDSVSASAVLSVVA 616



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 3/104 (2%)

Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           S +    + P F+ P  +    +E R      +      PT  + W K+   +  +  + 
Sbjct: 240 SAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 299

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
             F     +L I+H+   D+G+Y   A N LG    T S+RV A
Sbjct: 300 KNFE---KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 340



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            +  G    +EC+++     ++ V W  + + L S  R+    D     L +  V  +DSG
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 593

Query: 1916 EYTCKAINNLGQAVSSIRLNV 1936
             YTC A   L    +S  L+V
Sbjct: 594  TYTCVANTTLDSVSASAVLSV 614



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)

Query: 406 GKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV-V 463
           G+     CR   G P P + W  N  Q R   + +  V++  N  L  +NV   D+    
Sbjct: 160 GQSLVLPCRPPIGLPPPIIFWMDNSFQ-RLPQSER--VSQGLNGDLYFSNVLPEDTREDY 216

Query: 464 TCVARNKSGETAFQCR---LNVI--EKEQVVAPKFVERFSTLNVRE---GEPVVLNARAV 515
            C AR    +T  Q +   + VI  +  +   P F+      + +E   G  + L   A 
Sbjct: 217 ICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE 276

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
           G PTP I W K+   +   P+ R        TL I     +D+  YQC A+N  G+
Sbjct: 277 GLPTPIIYWAKEDGML---PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA 329



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + PR L P     +++  + A  +      S L  T+EW+   K       I   H+ 
Sbjct: 431  LAEPPRILTPANTLYQVIANRPALLDCAFFG-SPLP-TIEWFKGAKGSALHEDIYVLHEN 488

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            G   L+I   + + +G YT VARN  G A+    + ++
Sbjct: 489  G--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 524



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDIL 3892
            + Q +   V+    V FEC+V+      L + W ++ + LPS  R+    D     L + 
Sbjct: 530  VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVA 585

Query: 3893 YVYAEDSGEYICRA 3906
             V  +DSG Y C A
Sbjct: 586  DVSDDDSGTYTCVA 599



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q G    F+C++      +L V W ++ + +    R T   D     + ++ V D+D G
Sbjct: 538  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVADVSDDDSG 593

Query: 2448 VYMCRASNLL 2457
             Y C A+  L
Sbjct: 594  TYTCVANTTL 603



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 10/118 (8%)

Query: 378 ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT--WFINDRQIRDD 435
           + E  +EI +   A   VK  +   V  G M  F+C+V       +T  W  ++R++  D
Sbjct: 516 KNEVHLEIKD---ATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSD 572

Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
              +  V++  +H L++ +V+  DSG  TCVA       +    L+V+      AP +
Sbjct: 573 --ERFTVDK--DH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVY 625



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 651 GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYT 710
           G  + FE +++     ++ + WLK+ + + +  RFT         L +  ++  DSG YT
Sbjct: 541 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 596

Query: 711 CRAVSATGVAETKAVLHV---TPR-ATIERTSQHPETLQYIQQLE 751
           C A +        AVL V   TP  A +      P  L+   QL+
Sbjct: 597 CVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 641



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%)

Query: 1706 VITQAPVFTMPMKDI-RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            V+ + P    P   + +V  N+ A  +      G P   +EW +          +  +H+
Sbjct: 430  VLAEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHE 487

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
             G   L +     + +GTYTC A N+LG A
Sbjct: 488  NG--TLEIPVAQKDSTGTYTCVARNKLGMA 515



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/105 (23%), Positives = 45/105 (42%), Gaps = 6/105 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK-VEWFKNGQPVTIGHRFRPIHDFGYV 1502
            PR +T   ++  VI  +    +C       S L  +EWFK  +   +      +H+ G +
Sbjct: 435  PRILTPANTLYQVIANRPALLDCAF---FGSPLPTIEWFKGAKGSALHEDIYVLHENGTL 491

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
             + +     + +G YTC A N +G  +    L  +  T IV+  +
Sbjct: 492  EIPVAQ--KDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPE 534



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 7/110 (6%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVE-GQVLHLEGQVEPKNDPDLKIEWYFNG 2951
            AR   G   +    E     WI+    E+ +V+ G ++  E +V+  +   L + W  + 
Sbjct: 508  ARNKLGMAKNEVHLEIKDATWIVK-QPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDN 566

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + L    RF +  D     L + DV + DSG YTC A N   ++ ++S V
Sbjct: 567  RELPSDERFTVDKDH----LVVADVSDDDSGTYTCVA-NTTLDSVSASAV 611


>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
            7 protein.
          Length = 1070

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 87/336 (25%), Positives = 134/336 (39%), Gaps = 30/336 (8%)

Query: 4480 VFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
            V A +AE+  G   C +ANL  + ++         PS+    Q+  +  G+   LD    
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQ 436

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
             T    V W +N   +  D R ++ + +GT  +  +E Y  D   Y C++   AG     
Sbjct: 437  ATPKPTVVWYRNQMLISEDSRFEVFK-NGTLRINSVEVY--DGTWYRCMSSTPAGSIEAQ 493

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            A   V L   K  P PQ      P + +E  K+  V         C   G+  PT++W +
Sbjct: 494  ARVQV-LEKLKFTPPPQ------PQQCMEFDKEATVP--------CSATGREKPTIKWER 538

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA-GRVTVAAKLKVTQPDQ 4717
             D    P        T +  TL  +    +D G+Y C+A N   G++    +L V     
Sbjct: 539  ADGSSLPEWV-----TDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFIT 593

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777
                P  T      VY+G  A  + +     KP IQW  +  ++  T     +H   N  
Sbjct: 594  FKVEPERT-----TVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGS 648

Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            L+I +   ED+G +TC A  +     T A L V  K
Sbjct: 649  LVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 92/414 (22%), Positives = 156/414 (37%), Gaps = 50/414 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-IL 4468
            P +         +    Q       DG P P  +W+R+  P+ +      HT S+K   L
Sbjct: 128  PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQ--SNHTVSSKERNL 185

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             +R    E S +++  A +  G A  S N  +          ++ P      Q+V V   
Sbjct: 186  TLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAP------QDVVVARY 239

Query: 4529 QLVRLDTKVTGTKPIDVYWL------KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            +      + +   P  + WL         +   P +R   +  +G  +LL+ +  P+++G
Sbjct: 240  EEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANG--SLLLTQVRPRNAG 297

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y C+     G      E  + L   +D P            + EP   ++   G     
Sbjct: 298  IYRCIGQGQRGPP-IILEATLHLAEIEDMP------------LFEP---RVFTAGSEERV 341

Query: 4643 SC-KIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            +C    G P P+V W + G +L    + +Q       + L ++     D G Y C A N 
Sbjct: 342  TCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKG-----HELVLANIAESDAGVYTCHAANL 396

Query: 4701 AGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
            AG+      + V        +P+ L   +D  + EG+P        +  KPT+ W R   
Sbjct: 397  AGQRRQDVNITVA------TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQM 450

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            LI E   F++     N  L I +    D   + C ++T AG +E  A++ V  K
Sbjct: 451  LISEDSRFEVF---KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 48/181 (26%), Positives = 80/181 (44%), Gaps = 14/181 (7%)

Query: 399 QDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457
           + R  T G   R  C    G P P V W      +R   + ++   + G H L++ N+  
Sbjct: 329 EPRVFTAGSEERVTCLPPKGLPEPSVWW--EHAGVRLPTHGRVY--QKG-HELVLANIAE 383

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           SD+GV TC A N +G+      + V        P ++++     + EG+P  L+     T
Sbjct: 384 SDAGVYTCHAANLAGQRRQDVNITV-----ATVPSWLKKPQDSQLEEGKPGYLDCLTQAT 438

Query: 518 PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
           P P + W ++ + I  +    +  +G   TL I   +  D  WY+C +   AGS   +AR
Sbjct: 439 PKPTVVWYRNQMLISEDSRFEVFKNG---TLRINSVEVYDGTWYRCMSSTPAGSIEAQAR 495

Query: 578 L 578
           +
Sbjct: 496 V 496



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 76/327 (23%), Positives = 125/327 (38%), Gaps = 53/327 (16%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D ++   + P   +KP++S+L+EG            P+P V W++N   +   ++ E+  
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVF- 461

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
              + TLR+ + +  D   Y  ++  P G I            E+  + Q  + +  T  
Sbjct: 462 --KNGTLRINSVEVYDGTWYRCMSSTPAGSI------------EAQARVQVLEKLKFTPP 507

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            + ++ +E  ++A  P                    C  TGR  P + W   D     ++
Sbjct: 508 PQPQQCMEFDKEATVP--------------------CSATGREKPTIKWERADGSSLPEW 547

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARN-KSGETAFQCRLNVIEKEQVVAPKFVE 495
               + + +G   L    VT  D+G  TC+A N   G+     +L V      V   F  
Sbjct: 548 ----VTDNAG--TLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTV-----AVFITFKV 596

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQ-KDGV--PIIPNPELRIHTDGGASTLDIPR 552
                 V +G   +L   A G P P I W+ KD +  P    P + I  +G   +L I  
Sbjct: 597 EPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNG---SLVIHD 653

Query: 553 AKASDAAWYQCTAQNVAGSTATRARLY 579
               D+  Y C A N      T A LY
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLY 680



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 70/310 (22%), Positives = 120/310 (38%), Gaps = 44/310 (14%)

Query: 266 PKIAQKPRN-SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P + + P + +++Q       +  + G+PRP   WF++G  L +   +  +++     L 
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERN-LT 186

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +R      SG Y+  A +  G   +S    +    ES+                   R+ 
Sbjct: 187 LRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFA------------------RV- 227

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR---QIRDDYNHKIL 441
                LAPQ V V +  +        F C+ + +P P + W   D      R    H   
Sbjct: 228 ----VLAPQDVVVARYEEAM------FHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRR 277

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTL 500
                N +L++T V   ++G+  C+ + + G     +  L++ E E +  P F  R  T 
Sbjct: 278 ATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM--PLFEPRVFTA 335

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
                E  V      G P P + W+  GV +  +   R++  G    L +     SDA  
Sbjct: 336 G---SEERVTCLPPKGLPEPSVWWEHAGVRLPTHG--RVYQKG--HELVLANIAESDAGV 388

Query: 561 YQCTAQNVAG 570
           Y C A N+AG
Sbjct: 389 YTCHAANLAG 398



 Score = 55.2 bits (127), Expect = 6e-06
 Identities = 86/392 (21%), Positives = 154/392 (39%), Gaps = 45/392 (11%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF-VEDSAVFAAVA-E 4486
            R EVE  G P+  + W  +  P++++       F+  S L    V   +DS  F  VA +
Sbjct: 52   RCEVEAPG-PVH-VYWLLDGAPVQDTE----RRFAQGSSLSFAAVDRPQDSGTFQCVARD 105

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            +  G    SAN     K  +  G +V       A    +     V L   + G       
Sbjct: 106  DVTGEEARSANASFNIKWIEA-GPVV---LKHPASEAEIQPQTQVTLRCHIDGHPRPTYQ 161

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W ++G  +     N  +       L +  A P+ SG Y C A ++ G+A       +S+ 
Sbjct: 162  WFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSI- 219

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK--LIK 4664
                       A  +   ++   +D +VA  +   F C+   +P P++QW   D+  +  
Sbjct: 220  -----------ADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITN 268

Query: 4665 PSK--YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLKVTQPDQADNL 4721
             S+  + + +      +L +++  P + G Y+C+     G  + + A L + +    +++
Sbjct: 269  RSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAE---IEDM 325

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSK--IKPTIQWLREGALIPETPD-FQMIHEGNNAVL 4778
            P   P     V+     +  T +  K   +P++ W   G  +P     +Q  HE     L
Sbjct: 326  PLFEPR----VFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHE-----L 376

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            ++ N  E D G +TC A   AGQ      + V
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITV 408



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 11/133 (8%)

Query: 4414 TKKMQPCR--VFEHEQARFEVEFDGEPLPLIKWYREN---FPIKNSPDFQIHTFSTKSIL 4468
            T K++P R  V++   A  + E  G+P PLI+W  ++    P K  P  ++H F   S L
Sbjct: 593  TFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP--RMHIFQNGS-L 649

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK--RRQGRGGIVPPSFTLTAQNVNVT 4526
            +I  V  EDS  +  +A N        A L V +K    +  G   PP + +  Q + ++
Sbjct: 650  VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKM-IQTIGLS 708

Query: 4527 SGQLVRLDTKVTG 4539
             G  V     V G
Sbjct: 709  VGAAVAYIIAVLG 721



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/68 (35%), Positives = 33/68 (48%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDPK  ++W      ++ +     MH F   +L +  V PEDSG YTC A N      T 
Sbjct: 617  GDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTE 676

Query: 1798 STLFVQSK 1805
            + L+V  K
Sbjct: 677  APLYVVDK 684



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 39/183 (21%), Positives = 65/183 (35%), Gaps = 7/183 (3%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
           F+K    +D  +G+     C V       V W ++   ++D    +     S + A +  
Sbjct: 34  FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDT-ERRFAQGSSLSFAAVDR 92

Query: 454 NVTLSDSGVVTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVER-FSTLNVREGEPVVLN 511
                DSG   CVAR+  +GE A     +   K     P  ++   S   ++    V L 
Sbjct: 93  P---QDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               G P P   W +DG P + + +           L +  A    +  Y C A +  G 
Sbjct: 150 CHIDGHPRPTYQWFRDGTP-LSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQ 208

Query: 572 TAT 574
             +
Sbjct: 209 ACS 211



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 4/67 (5%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE-QTGDVSLLIKQIGPGDEGE 143
           QG  A  + + +G+P P++ W + K  +++  K   R +  Q G  SL+I  + P D G 
Sbjct: 605 QGHTALLQCEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNG--SLVIHDVAPEDSGR 661

Query: 144 YTCTARN 150
           YTC A N
Sbjct: 662 YTCIAGN 668



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + +G TA   C     GDP   ++W   +++++ +    + H F   S+ I  V  ED G
Sbjct: 603  VYQGHTALLQCEA--QGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG 660

Query: 2448 VYMCRASN 2455
             Y C A N
Sbjct: 661  RYTCIAGN 668



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 6/90 (6%)

Query: 3982 QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKP-LLHKNRFTP-IYDFGYVAMNFGWVY 4039
            +T++ +  T   +C+    GDP   ++W   GK  +L   +  P ++ F   ++    V 
Sbjct: 600  RTTVYQGHTALLQCEAQ--GDPKPLIQW--KGKDRILDPTKLGPRMHIFQNGSLVIHDVA 655

Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            PEDSG Y C A N   +  T+A +    KP
Sbjct: 656  PEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            A LA  RR  V  T    P W+     + QL EG+  +L+   +    P   + WY N  
Sbjct: 394  ANLAGQRRQDVNITVATVPSWLKK-PQDSQLEEGKPGYLDCLTQATPKPT--VVWYRNQM 450

Query: 2953 VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            ++ + SRF++  + G + ++ V+VY  D   Y C +    G     + V    K
Sbjct: 451  LISEDSRFEVFKN-GTLRINSVEVY--DGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V +G      C   G P P + W   DR I D       ++   N +L+I +V   DSG 
Sbjct: 603 VYQGHTALLQCEAQGDPKPLIQWKGKDR-ILDPTKLGPRMHIFQNGSLVIHDVAPEDSGR 661

Query: 463 VTCVARNKSGETAFQCRLNVIEK 485
            TC+A N       +  L V++K
Sbjct: 662 YTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 62/285 (21%), Positives = 99/285 (34%), Gaps = 18/285 (6%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E  P + +     A             + G+P P   W R   PL +       +   + 
Sbjct: 125 EAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQS---NHTVSSK 181

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS----VYIQPEGXXXXXXXXXXXXXYRHVS 183
           + +L ++  GP   G Y+C A + +G+A  S    + I  E               R+  
Sbjct: 182 ERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARY-E 240

Query: 184 ETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
           E + H  +  Q   + Q     +   TN +         V      LL +V  R +   R
Sbjct: 241 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR 300

Query: 244 YVGESD--VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWF 300
            +G+      I  E    L  +    + + PR      G++ +   +   G P P V W 
Sbjct: 301 CIGQGQRGPPIILEATLHLAEIEDMPLFE-PR--VFTAGSEERVTCLPPKGLPEPSVWWE 357

Query: 301 KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             G RL     H  +    H  L + N  +SD+G YT  A N  G
Sbjct: 358 HAGVRL---PTHGRVYQKGH-ELVLANIAESDAGVYTCHAANLAG 398



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E  GD    ++W    R ++ +        F   +L I  V   D+G YTC A N+    
Sbjct: 614  EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 994  TTSANLTIVTKKDIIAESQHPG 1015
             T A L +V  K +  ES+ PG
Sbjct: 674  HTEAPLYVV-DKPVPEESEGPG 694



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/77 (27%), Positives = 37/77 (48%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           E  GDP   I+W    + ++ +     +  F   SL +  +  +DSG YTC A ++  + 
Sbjct: 614 EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 721 ETKAVLHVTPRATIERT 737
            T+A L+V  +   E +
Sbjct: 674 HTEAPLYVVDKPVPEES 690



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 11/128 (8%)

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
            R  C + PK  P+  + W   G  LP+  R   VY  G   L +  +   D+G Y C A 
Sbjct: 340  RVTC-LPPKGLPEPSVWWEHAGVRLPTHGR---VYQKGH-ELVLANIAESDAGVYTCHAA 394

Query: 3908 NDFGEDFTKATISCKKLPDIILQ---NQVPRGMK-RSEALTQM--EATIKKYTSEVYLTE 3961
            N  G+      I+   +P  + +   +Q+  G     + LTQ   + T+  Y +++ ++E
Sbjct: 395  NLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISE 454

Query: 3962 DDLYDVDK 3969
            D  ++V K
Sbjct: 455  DSRFEVFK 462



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 1/95 (1%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q E + DP   I+W    ++L+          F   +L + DV   DSG YTC A N   
Sbjct: 612  QCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNL 3028
               T + +Y   K  + E ++ P      + IQ +
Sbjct: 672  IKHTEAPLYVVDKP-VPEESEGPGSPPPYKMIQTI 705



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 5/62 (8%)

Query: 1738 GDPKLRVEWLRNGVPIE--ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G P+   +W R+G P+    SN   +  +     L ++   PE SG Y+C A +  G+A 
Sbjct: 154  GHPRPTYQWFRDGTPLSDGQSNHTVSSKERN---LTLRPAGPEHSGLYSCCAHSAFGQAC 210

Query: 1796 TS 1797
            +S
Sbjct: 211  SS 212



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGK---PIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
            +G    L+C  Q  GD    ++W    +   P K G R    + F   +L +  V PEDS
Sbjct: 605  QGHTALLQCEAQ--GDPKPLIQWKGKDRILDPTKLGPRM---HIFQNGSLVIHDVAPEDS 659

Query: 1381 GVYTCQATNQLGEAVTSCALRVIAK 1405
            G YTC A N      T   L V+ K
Sbjct: 660  GRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++  P+   H  S  ++     V L   ++    P    +WF++G  L+ G +   T   
Sbjct: 124  IEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTY--QWFRDGTPLSDG-QSNHTVSS 180

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                L++     + SG+Y+C A +  G+A S+ +  +
Sbjct: 181  KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)

Query: 1326 TNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTC 1385
            T V L C +   G      +WF +G P+  G         +   L L    PE SG+Y+C
Sbjct: 144  TQVTLRCHID--GHPRPTYQWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSC 200

Query: 1386 QATNQLGEAVTS 1397
             A +  G+A +S
Sbjct: 201  CAHSAFGQACSS 212



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +W +DG P+       T  +     LT++      +G Y+C A++A GQA +S N T+
Sbjct: 161  QWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217


>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
            7 protein.
          Length = 1070

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 87/336 (25%), Positives = 134/336 (39%), Gaps = 30/336 (8%)

Query: 4480 VFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
            V A +AE+  G   C +ANL  + ++         PS+    Q+  +  G+   LD    
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQ 436

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
             T    V W +N   +  D R ++ + +GT  +  +E Y  D   Y C++   AG     
Sbjct: 437  ATPKPTVVWYRNQMLISEDSRFEVFK-NGTLRINSVEVY--DGTWYRCMSSTPAGSIEAQ 493

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            A   V L   K  P PQ      P + +E  K+  V         C   G+  PT++W +
Sbjct: 494  ARVQV-LEKLKFTPPPQ------PQQCMEFDKEATVP--------CSATGREKPTIKWER 538

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA-GRVTVAAKLKVTQPDQ 4717
             D    P        T +  TL  +    +D G+Y C+A N   G++    +L V     
Sbjct: 539  ADGSSLPEWV-----TDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFIT 593

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777
                P  T      VY+G  A  + +     KP IQW  +  ++  T     +H   N  
Sbjct: 594  FKVEPERT-----TVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGS 648

Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            L+I +   ED+G +TC A  +     T A L V  K
Sbjct: 649  LVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 92/414 (22%), Positives = 156/414 (37%), Gaps = 50/414 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-IL 4468
            P +         +    Q       DG P P  +W+R+  P+ +      HT S+K   L
Sbjct: 128  PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQ--SNHTVSSKERNL 185

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             +R    E S +++  A +  G A  S N  +          ++ P      Q+V V   
Sbjct: 186  TLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAP------QDVVVARY 239

Query: 4529 QLVRLDTKVTGTKPIDVYWL------KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            +      + +   P  + WL         +   P +R   +  +G  +LL+ +  P+++G
Sbjct: 240  EEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANG--SLLLTQVRPRNAG 297

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y C+     G      E  + L   +D P            + EP   ++   G     
Sbjct: 298  IYRCIGQGQRGPP-IILEATLHLAEIEDMP------------LFEP---RVFTAGSEERV 341

Query: 4643 SC-KIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            +C    G P P+V W + G +L    + +Q       + L ++     D G Y C A N 
Sbjct: 342  TCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKG-----HELVLANIAESDAGVYTCHAANL 396

Query: 4701 AGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
            AG+      + V        +P+ L   +D  + EG+P        +  KPT+ W R   
Sbjct: 397  AGQRRQDVNITVA------TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQM 450

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            LI E   F++     N  L I +    D   + C ++T AG +E  A++ V  K
Sbjct: 451  LISEDSRFEVF---KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 48/181 (26%), Positives = 80/181 (44%), Gaps = 14/181 (7%)

Query: 399 QDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457
           + R  T G   R  C    G P P V W      +R   + ++   + G H L++ N+  
Sbjct: 329 EPRVFTAGSEERVTCLPPKGLPEPSVWW--EHAGVRLPTHGRVY--QKG-HELVLANIAE 383

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           SD+GV TC A N +G+      + V        P ++++     + EG+P  L+     T
Sbjct: 384 SDAGVYTCHAANLAGQRRQDVNITV-----ATVPSWLKKPQDSQLEEGKPGYLDCLTQAT 438

Query: 518 PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
           P P + W ++ + I  +    +  +G   TL I   +  D  WY+C +   AGS   +AR
Sbjct: 439 PKPTVVWYRNQMLISEDSRFEVFKNG---TLRINSVEVYDGTWYRCMSSTPAGSIEAQAR 495

Query: 578 L 578
           +
Sbjct: 496 V 496



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 76/327 (23%), Positives = 125/327 (38%), Gaps = 53/327 (16%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D ++   + P   +KP++S+L+EG            P+P V W++N   +   ++ E+  
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVF- 461

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
              + TLR+ + +  D   Y  ++  P G I            E+  + Q  + +  T  
Sbjct: 462 --KNGTLRINSVEVYDGTWYRCMSSTPAGSI------------EAQARVQVLEKLKFTPP 507

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            + ++ +E  ++A  P                    C  TGR  P + W   D     ++
Sbjct: 508 PQPQQCMEFDKEATVP--------------------CSATGREKPTIKWERADGSSLPEW 547

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARN-KSGETAFQCRLNVIEKEQVVAPKFVE 495
               + + +G   L    VT  D+G  TC+A N   G+     +L V      V   F  
Sbjct: 548 ----VTDNAG--TLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTV-----AVFITFKV 596

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQ-KDGV--PIIPNPELRIHTDGGASTLDIPR 552
                 V +G   +L   A G P P I W+ KD +  P    P + I  +G   +L I  
Sbjct: 597 EPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNG---SLVIHD 653

Query: 553 AKASDAAWYQCTAQNVAGSTATRARLY 579
               D+  Y C A N      T A LY
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLY 680



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 70/310 (22%), Positives = 120/310 (38%), Gaps = 44/310 (14%)

Query: 266 PKIAQKPRN-SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P + + P + +++Q       +  + G+PRP   WF++G  L +   +  +++     L 
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERN-LT 186

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +R      SG Y+  A +  G   +S    +    ES+                   R+ 
Sbjct: 187 LRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFA------------------RV- 227

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR---QIRDDYNHKIL 441
                LAPQ V V +  +        F C+ + +P P + W   D      R    H   
Sbjct: 228 ----VLAPQDVVVARYEEAM------FHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRR 277

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTL 500
                N +L++T V   ++G+  C+ + + G     +  L++ E E +  P F  R  T 
Sbjct: 278 ATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM--PLFEPRVFTA 335

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
                E  V      G P P + W+  GV +  +   R++  G    L +     SDA  
Sbjct: 336 G---SEERVTCLPPKGLPEPSVWWEHAGVRLPTHG--RVYQKG--HELVLANIAESDAGV 388

Query: 561 YQCTAQNVAG 570
           Y C A N+AG
Sbjct: 389 YTCHAANLAG 398



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 86/392 (21%), Positives = 155/392 (39%), Gaps = 45/392 (11%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF-VEDSAVFAAVA-E 4486
            R EVE  G P+  + W  +  P++++       F+  S L    V  ++DS  F  VA +
Sbjct: 52   RCEVEAPG-PVH-VYWLLDGAPVQDTE----RRFAQGSSLSFAAVDRLQDSGTFQCVARD 105

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            +  G    SAN     K  +  G +V       A    +     V L   + G       
Sbjct: 106  DVTGEEARSANASFNIKWIEA-GPVV---LKHPASEAEIQPQTQVTLRCHIDGHPRPTYQ 161

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W ++G  +     N  +       L +  A P+ SG Y C A ++ G+A       +S+ 
Sbjct: 162  WFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSI- 219

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK--LIK 4664
                       A  +   ++   +D +VA  +   F C+   +P P++QW   D+  +  
Sbjct: 220  -----------ADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITN 268

Query: 4665 PSK--YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLKVTQPDQADNL 4721
             S+  + + +      +L +++  P + G Y+C+     G  + + A L + +    +++
Sbjct: 269  RSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAE---IEDM 325

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSK--IKPTIQWLREGALIPETPD-FQMIHEGNNAVL 4778
            P   P     V+     +  T +  K   +P++ W   G  +P     +Q  HE     L
Sbjct: 326  PLFEPR----VFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHE-----L 376

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            ++ N  E D G +TC A   AGQ      + V
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITV 408



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 11/133 (8%)

Query: 4414 TKKMQPCR--VFEHEQARFEVEFDGEPLPLIKWYREN---FPIKNSPDFQIHTFSTKSIL 4468
            T K++P R  V++   A  + E  G+P PLI+W  ++    P K  P  ++H F   S L
Sbjct: 593  TFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP--RMHIFQNGS-L 649

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK--RRQGRGGIVPPSFTLTAQNVNVT 4526
            +I  V  EDS  +  +A N        A L V +K    +  G   PP + +  Q + ++
Sbjct: 650  VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKM-IQTIGLS 708

Query: 4527 SGQLVRLDTKVTG 4539
             G  V     V G
Sbjct: 709  VGAAVAYIIAVLG 721



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 40/183 (21%), Positives = 66/183 (36%), Gaps = 7/183 (3%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
           F+K    +D  +G+     C V       V W ++   ++D    +     S + A +  
Sbjct: 34  FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDT-ERRFAQGSSLSFAAVDR 92

Query: 454 NVTLSDSGVVTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVER-FSTLNVREGEPVVLN 511
              L DSG   CVAR+  +GE A     +   K     P  ++   S   ++    V L 
Sbjct: 93  ---LQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               G P P   W +DG P + + +           L +  A    +  Y C A +  G 
Sbjct: 150 CHIDGHPRPTYQWFRDGTP-LSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQ 208

Query: 572 TAT 574
             +
Sbjct: 209 ACS 211



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/68 (35%), Positives = 33/68 (48%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDPK  ++W      ++ +     MH F   +L +  V PEDSG YTC A N      T 
Sbjct: 617  GDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTE 676

Query: 1798 STLFVQSK 1805
            + L+V  K
Sbjct: 677  APLYVVDK 684



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 4/67 (5%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE-QTGDVSLLIKQIGPGDEGE 143
           QG  A  + + +G+P P++ W + K  +++  K   R +  Q G  SL+I  + P D G 
Sbjct: 605 QGHTALLQCEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNG--SLVIHDVAPEDSGR 661

Query: 144 YTCTARN 150
           YTC A N
Sbjct: 662 YTCIAGN 668



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + +G TA   C     GDP   ++W   +++++ +    + H F   S+ I  V  ED G
Sbjct: 603  VYQGHTALLQCEA--QGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG 660

Query: 2448 VYMCRASN 2455
             Y C A N
Sbjct: 661  RYTCIAGN 668



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 6/90 (6%)

Query: 3982 QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKP-LLHKNRFTP-IYDFGYVAMNFGWVY 4039
            +T++ +  T   +C+    GDP   ++W   GK  +L   +  P ++ F   ++    V 
Sbjct: 600  RTTVYQGHTALLQCEAQ--GDPKPLIQW--KGKDRILDPTKLGPRMHIFQNGSLVIHDVA 655

Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            PEDSG Y C A N   +  T+A +    KP
Sbjct: 656  PEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            A LA  RR  V  T    P W+     + QL EG+  +L+   +    P   + WY N  
Sbjct: 394  ANLAGQRRQDVNITVATVPSWLKK-PQDSQLEEGKPGYLDCLTQATPKPT--VVWYRNQM 450

Query: 2953 VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            ++ + SRF++  + G + ++ V+VY  D   Y C +    G     + V    K
Sbjct: 451  LISEDSRFEVFKN-GTLRINSVEVY--DGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V +G      C   G P P + W   DR I D       ++   N +L+I +V   DSG 
Sbjct: 603 VYQGHTALLQCEAQGDPKPLIQWKGKDR-ILDPTKLGPRMHIFQNGSLVIHDVAPEDSGR 661

Query: 463 VTCVARNKSGETAFQCRLNVIEK 485
            TC+A N       +  L V++K
Sbjct: 662 YTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 62/285 (21%), Positives = 99/285 (34%), Gaps = 18/285 (6%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E  P + +     A             + G+P P   W R   PL +       +   + 
Sbjct: 125 EAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQS---NHTVSSK 181

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS----VYIQPEGXXXXXXXXXXXXXYRHVS 183
           + +L ++  GP   G Y+C A + +G+A  S    + I  E               R+  
Sbjct: 182 ERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARY-E 240

Query: 184 ETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
           E + H  +  Q   + Q     +   TN +         V      LL +V  R +   R
Sbjct: 241 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR 300

Query: 244 YVGESD--VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWF 300
            +G+      I  E    L  +    + + PR      G++ +   +   G P P V W 
Sbjct: 301 CIGQGQRGPPIILEATLHLAEIEDMPLFE-PR--VFTAGSEERVTCLPPKGLPEPSVWWE 357

Query: 301 KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             G RL     H  +    H  L + N  +SD+G YT  A N  G
Sbjct: 358 HAGVRL---PTHGRVYQKGH-ELVLANIAESDAGVYTCHAANLAG 398



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E  GD    ++W    R ++ +        F   +L I  V   D+G YTC A N+    
Sbjct: 614  EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 994  TTSANLTIVTKKDIIAESQHPG 1015
             T A L +V  K +  ES+ PG
Sbjct: 674  HTEAPLYVV-DKPVPEESEGPG 694



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/77 (27%), Positives = 37/77 (48%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           E  GDP   I+W    + ++ +     +  F   SL +  +  +DSG YTC A ++  + 
Sbjct: 614 EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 721 ETKAVLHVTPRATIERT 737
            T+A L+V  +   E +
Sbjct: 674 HTEAPLYVVDKPVPEES 690



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 17/125 (13%)

Query: 1288 IQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHL-----ECRLQPVGDQTM 1342
            +  L+D+       R+D+T  +A + + A  NI+ +E   V L     E  +QP    T+
Sbjct: 90   VDRLQDSGTFQCVARDDVTGEEA-RSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTL 148

Query: 1343 RV----------EWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            R           +WF +G P+  G         +   L L    PE SG+Y+C A +  G
Sbjct: 149  RCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFG 207

Query: 1393 EAVTS 1397
            +A +S
Sbjct: 208  QACSS 212



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 11/128 (8%)

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
            R  C + PK  P+  + W   G  LP+  R   VY  G   L +  +   D+G Y C A 
Sbjct: 340  RVTC-LPPKGLPEPSVWWEHAGVRLPTHGR---VYQKGH-ELVLANIAESDAGVYTCHAA 394

Query: 3908 NDFGEDFTKATISCKKLPDIILQ---NQVPRGMK-RSEALTQM--EATIKKYTSEVYLTE 3961
            N  G+      I+   +P  + +   +Q+  G     + LTQ   + T+  Y +++ ++E
Sbjct: 395  NLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISE 454

Query: 3962 DDLYDVDK 3969
            D  ++V K
Sbjct: 455  DSRFEVFK 462



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 1/95 (1%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q E + DP   I+W    ++L+          F   +L + DV   DSG YTC A N   
Sbjct: 612  QCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNL 3028
               T + +Y   K  + E ++ P      + IQ +
Sbjct: 672  IKHTEAPLYVVDKP-VPEESEGPGSPPPYKMIQTI 705



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 5/62 (8%)

Query: 1738 GDPKLRVEWLRNGVPIE--ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G P+   +W R+G P+    SN   +  +     L ++   PE SG Y+C A +  G+A 
Sbjct: 154  GHPRPTYQWFRDGTPLSDGQSNHTVSSKERN---LTLRPAGPEHSGLYSCCAHSAFGQAC 210

Query: 1796 TS 1797
            +S
Sbjct: 211  SS 212



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGK---PIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
            +G    L+C  Q  GD    ++W    +   P K G R    + F   +L +  V PEDS
Sbjct: 605  QGHTALLQCEAQ--GDPKPLIQWKGKDRILDPTKLGPRM---HIFQNGSLVIHDVAPEDS 659

Query: 1381 GVYTCQATNQLGEAVTSCALRVIAK 1405
            G YTC A N      T   L V+ K
Sbjct: 660  GRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++  P+   H  S  ++     V L   ++    P    +WF++G  L+ G +   T   
Sbjct: 124  IEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTY--QWFRDGTPLSDG-QSNHTVSS 180

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                L++     + SG+Y+C A +  G+A S+ +  +
Sbjct: 181  KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +W +DG P+       T  +     LT++      +G Y+C A++A GQA +S N T+
Sbjct: 161  QWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217


>AL049946-1|CAB43220.1|  584|Homo sapiens hypothetical protein
           protein.
          Length = 584

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 78/292 (26%), Positives = 130/292 (44%), Gaps = 42/292 (14%)

Query: 288 QLSGNPRPRVTWFKNGQRLI--NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           +  G P P+VTW     ++I  +S K++I   +   TL ++  Q+SDSG+YT        
Sbjct: 125 EAKGEPMPKVTWLSPTNKVIPTSSEKYQI---YQDGTLLIQKAQRSDSGNYT-------- 173

Query: 346 CIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTE 405
           C+V +          S  +D+++ +I           + +    +      +   R++  
Sbjct: 174 CLVRN----------SAGEDRKTVWI----------HVNVQPPKINGNPNPITTVREIAA 213

Query: 406 GKMTRF-DCRVTGRPYPEVTWFINDRQIRDD--YNHKILVNESGNHALMITNVTLSDSGV 462
           G   +  DC+  G P P V W   +  +     Y ++I V+  GN +L I ++  SDS  
Sbjct: 214 GGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVH--GNGSLDIRSLRKSDSVQ 271

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPR 521
           + C+ARN+ GE     +L V+E  +   P F +  S  +    G  + LN  A GTPTP 
Sbjct: 272 LVCMARNEGGEARLILQLTVLEPME--KPIFHDPISEKITAMAGHTISLNCSAAGTPTPS 329

Query: 522 ITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
           + W   +G  +    +L+         L I    + DA  Y+C A+N AG T
Sbjct: 330 LVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHT 381



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 92/348 (26%), Positives = 128/348 (36%), Gaps = 21/348 (6%)

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL---TAQNVNVTSGQ 4529
            VF   +  F  V     G   C A   V +   + R  +V    T+   T   V V  G 
Sbjct: 59   VFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTCLAVQVPYGD 118

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLLILEAYPQDSGKYECVA 4588
            +V +  +  G     V WL    KV P    K  + +DGT  LLI +A   DSG Y C+ 
Sbjct: 119  VVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGT--LLIQKAQRSDSGNYTCLV 176

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             NSAGE R      V +      PK      N  P  I  +++ I A G      CK  G
Sbjct: 177  RNSAGEDR----KTVWIHVNVQPPK-----INGNPNPITTVRE-IAAGGSRKLIDCKAEG 226

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTA-DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             P P V W   + ++ P+ Y+    T     +L I      D     C+A N  G   + 
Sbjct: 227  IPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLI 286

Query: 4708 AKLKVTQPDQADNLPALTPLRD-IVVYEGQPAQFKTQITSKIKPTIQW-LREGALIPETP 4765
             +L V +P +        P+ + I    G              P++ W L  G  +    
Sbjct: 287  LQLTVLEPMEKPIFH--DPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQ 344

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              Q  +   + +L I      D G + C A  AAG  E    L V  K
Sbjct: 345  QLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLK 392



 Score = 74.1 bits (174), Expect = 1e-11
 Identities = 91/386 (23%), Positives = 142/386 (36%), Gaps = 34/386 (8%)

Query: 4433 EFDGEPLPLIKWYRENFPI--KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E  GEP+P + W      +   +S  +QI+   T   L+I++    DS  +  +  N  G
Sbjct: 125  EAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGT---LLIQKAQRSDSGNYTCLVRNSAG 181

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LK 4549
              + +  + V  +  +  G    P+   T + +    G    +D K  G     V W   
Sbjct: 182  EDRKTVWIHVNVQPPKINGN---PNPITTVREI-AAGGSRKLIDCKAEGIPTPRVLWAFP 237

Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             G  +        +   G  +L I      DS +  C+A N  GEAR   +  V  P  K
Sbjct: 238  EGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEK 297

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWY--KGDKLIKPS 4666
                         P   +P+ +KI A  G  I  +C   G P P++ W    G  L    
Sbjct: 298  -------------PIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQ 344

Query: 4667 KYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNLPALT 4725
            +  +    AD   L IS     D G Y+CVA N+AG       LKV  +P+ +     L 
Sbjct: 345  QLQRFYHKADGM-LHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEASKQYHNL- 402

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD-FQMIHEGNNAVLLIGNTY 4784
                + +  G+  +         +    W     +  E P     +   +N  L +    
Sbjct: 403  ----VSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREAS 458

Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVV 4810
              D GT+ CR  T  G   TS  ++V
Sbjct: 459  VFDRGTYVCRMETEYGPSVTSIPVIV 484



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 61/207 (29%), Positives = 89/207 (42%), Gaps = 17/207 (8%)

Query: 373 DTQQRETEERIEISEKALAPQFV--KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430
           + Q  + E R+ + +   AP  +  K C    V  G +    C   G P P+VTW     
Sbjct: 83  ENQVGKDEMRVRV-KVVTAPATIRNKTCLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTN 141

Query: 431 QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490
           ++    + K  + + G   L+I     SDSG  TC+ RN +GE     R  V     V  
Sbjct: 142 KVIPTSSEKYQIYQDG--TLLIQKAQRSDSGNYTCLVRNSAGED----RKTVWIHVNVQP 195

Query: 491 PKFVERFSTL-NVRE----GEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL--RIHTDG 543
           PK     + +  VRE    G   +++ +A G PTPR+ W      ++P P    RI   G
Sbjct: 196 PKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHG 255

Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAG 570
             S LDI   + SD+    C A+N  G
Sbjct: 256 NGS-LDIRSLRKSDSVQLVCMARNEGG 281



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 51/183 (27%), Positives = 82/183 (44%), Gaps = 21/183 (11%)

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG----------NHA 449
           D  V  G   + DC  TG P PE++W + D  + + +      ++SG          N  
Sbjct: 8   DHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQS---DDSGGRTKRYVVFNNGT 64

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L    V + + G  TC A N+ G+   + R+ V+     +  K       + V  G+ V 
Sbjct: 65  LYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNK---TCLAVQVPYGDVVT 121

Query: 510 LNARAVGTPTPRITWQKDGVPIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           +   A G P P++TW      +IP  + + +I+ DG   TL I +A+ SD+  Y C  +N
Sbjct: 122 VACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDG---TLLIQKAQRSDSGNYTCLVRN 178

Query: 568 VAG 570
            AG
Sbjct: 179 SAG 181



 Score = 54.4 bits (125), Expect = 1e-05
 Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 11/190 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFY-NGKTIEASHRIRTVYAFGMV 3106
            P F     + +    G       S   T   S+V  W   NG  +++  +++  Y     
Sbjct: 298  PIFHDPISEKITAMAGHTISLNCSAAGTPTPSLV--WVLPNGTDLQSGQQLQRFYHKADG 355

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I G  + D+G Y C A N  G  E  V L+      G KP  +    N+  + +G++
Sbjct: 356  MLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV-----GLKPEASKQYHNLVSIINGET 410

Query: 3167 AHFECTVVPVDDPDMKIEW-YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                CT  P      +  W   NG  +     +  VS      L +      D G YVCR
Sbjct: 411  LKLPCT--PPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCR 468

Query: 3226 AYNKYGEDFT 3235
               +YG   T
Sbjct: 469  METEYGPSVT 478



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 72/305 (23%), Positives = 119/305 (39%), Gaps = 27/305 (8%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT------GDVSLLIKQIGPG 139
           GG+ K +    G P P +SW+     LV     S     +T       + +L   ++G  
Sbjct: 14  GGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMR 73

Query: 140 DEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTE 199
           +EG+YTC A NQ G+    V ++                     + V   A   +G   E
Sbjct: 74  EEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTCLAVQVPYGDVVT-VACEAKG---E 129

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRES-----ITKRYVGESDVQIST 254
              +   ++ TN    +S++ +++      L+++    +S     + +   GE    +  
Sbjct: 130 PMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWI 189

Query: 255 EIDRSLGPVSPPKIAQKPRN-SKLQE----GADAQFQVQLSGNPRPRVTW-FKNGQRLIN 308
            ++     V PPKI   P   + ++E    G+      +  G P PRV W F  G  L  
Sbjct: 190 HVN-----VQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPA 244

Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYV-QDQR 367
                 IT H + +L +R+ +KSDS     +A N  G       L V  P E  +  D  
Sbjct: 245 PYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPI 304

Query: 368 SQYIT 372
           S+ IT
Sbjct: 305 SEKIT 309



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 7/193 (3%)

Query: 3039 QPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR 3098
            QP    G P   TTV ++I      ++   +A  IPT     V+  F  G  + A +   
Sbjct: 194  QPPKINGNPNPITTV-REIAAGGSRKLIDCKAEGIPT---PRVLWAFPEGVVLPAPYYGN 249

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
             +   G   L+I   + +DS    C A N+ G+A + ++L  ++    +KP F   I   
Sbjct: 250  RITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPM--EKPIFHDPISEK 307

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
                 G +    C+      P + +    NG  ++   +++        +L I+   + D
Sbjct: 308  ITAMAGHTISLNCSAAGTPTPSL-VWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVD 366

Query: 3219 SGEYVCRAYNKYG 3231
            +G Y C A N  G
Sbjct: 367  AGAYRCVARNAAG 379



 Score = 44.4 bits (100), Expect = 0.010
 Identities = 46/199 (23%), Positives = 74/199 (37%), Gaps = 14/199 (7%)

Query: 381 ERIEISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
           ER+   +  L P+  K   +   +  G+  +  C   G      +W + +    +     
Sbjct: 382 ERLVSLKVGLKPEASKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTL 441

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
             V+   N  L +   ++ D G   C    + G +     + VI     +     E    
Sbjct: 442 GRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITS---EPTPV 498

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQ-------KDGVPIIPNPELRIHTDGGASTLDIPR 552
           +  R G  V LN  A+G P   ITW+       K GV         +H  G   +L I  
Sbjct: 499 IYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQG---SLTIQH 555

Query: 553 AKASDAAWYQCTAQNVAGS 571
           A   DA +Y+C A+N+ GS
Sbjct: 556 ATQRDAGFYKCMAKNILGS 574



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 4/100 (4%)

Query: 1975 VEKPQFGKPI-KNAEVTEGHPVHLEATLTPVNDPTMRVEWYC-NGRPVQQGHRFKTTYDF 2032
            +EKP F  PI +      GH + L  +      PT  + W   NG  +Q G + +  Y  
Sbjct: 295  MEKPIFHDPISEKITAMAGHTISLNCSAA--GTPTPSLVWVLPNGTDLQSGQQLQRFYHK 352

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
                L I    + D G Y C A NA G      S+KV  K
Sbjct: 353  ADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLK 392



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 5/93 (5%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEW-FHNGRSVTVGSRFKTYYDFGF 1234
            KP+F  P+S       G  I L C     G PT  + W   NG  +  G + + +Y    
Sbjct: 297  KPIFHDPISEKITAMAGHTISLNC--SAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKAD 354

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267
              L I   +S D G Y  R V    + HT  +V
Sbjct: 355  GMLHISGLSSVDAGAY--RCVARNAAGHTERLV 385



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 3/106 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEW-LKDGRPVEASSRITT 960
            V E  +KP F  PI ++I+   G            G  T  + W L +G  +++  ++  
Sbjct: 291  VLEPMEKPIFHDPISEKITAMAGHTISLNC--SAAGTPTPSLVWVLPNGTDLQSGQQLQR 348

Query: 961  FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
            F++     L I  ++  DAG Y C A NA G      +L +  K +
Sbjct: 349  FYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPE 394



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 2/73 (2%)

Query: 84  AQGGNAKF-EGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
           A GG+ K  + K  G PTP V W   +  ++    Y  R     G+ SL I+ +   D  
Sbjct: 212 AAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVH-GNGSLDIRSLRKSDSV 270

Query: 143 EYTCTARNQYGEA 155
           +  C ARN+ GEA
Sbjct: 271 QLVCMARNEGGEA 283



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF-NGKQITSANRIQTYHDFG 1099
            +KP F  P+  + KI                  T ++ W   NG  + S  ++Q ++   
Sbjct: 296  EKPIFHDPI--SEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKA 353

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
               L I+ + + D+G Y  VARNAAG  +   S+ V
Sbjct: 354  DGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 389



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 41/203 (20%), Positives = 74/203 (36%), Gaps = 13/203 (6%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFY-NGKTIEASHRIRTVYAF 3103
            G  PE +  + ++V I  G+      +  P G       W   NG  +E    +  V   
Sbjct: 390  GLKPEASKQYHNLVSIINGETLKLPCT--PPGAGQGRFSWTLPNGMHLEGPQTLGRVSLL 447

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                L +      D GTY CR   ++G +  S+ +  +       PR T+    +   + 
Sbjct: 448  DNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVI----AYPPRITSEPTPVIYTRP 503

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV----VLDIAYTQNHDS 3219
            G +    C  + +   D+  E   +   ++   + +   +  F+     L I +    D+
Sbjct: 504  GNTVKLNCMAMGIPKADITWE-LPDKSHLKAGVQARLYGN-RFLHPQGSLTIQHATQRDA 561

Query: 3220 GEYVCRAYNKYGEDFTRATINCY 3242
            G Y C A N  G D     I+ +
Sbjct: 562  GFYKCMAKNILGSDSKTTYIHVF 584



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 46/167 (27%), Positives = 71/167 (42%), Gaps = 11/167 (6%)

Query: 1796 TSSTLF-VQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVN-QAPRFITQLNGP 1853
            TSS  + +    +L ++    S       L  +S  + R+ V + VN Q P+     N  
Sbjct: 146  TSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPI 205

Query: 1854 TKLSE----GQSAHYECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTSNDFGFAALDILT 1908
            T + E    G     +C+ E  P P  RV W F  G VL + +        G  +LDI +
Sbjct: 206  TTVREIAAGGSRKLIDCKAEGIPTP--RVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRS 263

Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            +   DS +  C A N  G+A   ++L V   E + +   H+   EKI
Sbjct: 264  LRKSDSVQLVCMARNEGGEARLILQLTV--LEPMEKPIFHDPISEKI 308



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 3/99 (3%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYW-NGKSLKAGSRFRTFC 3473
            E  + P+F  P+S       G           T  P+L   W   NG  L++G + + F 
Sbjct: 293  EPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLV--WVLPNGTDLQSGQQLQRFY 350

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
                 +L IS     D+G Y C A N  G      S+KV
Sbjct: 351  HKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 389



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 1/95 (1%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            + PIF   +      + G  + L         P+L +    NG  L +G +L+  +    
Sbjct: 296  EKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSL-VWVLPNGTDLQSGQQLQRFYHKAD 354

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
              L I+ L + D+G Y C A N  G      S+K+
Sbjct: 355  GMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 389



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 637 PQFIVPL-KSVTAMEGGKIHFETRIEPVGDPTMKIEW-LKNGQSIEASSRFTSIFRFGYI 694
           P F  P+ + +TAM G  I         G PT  + W L NG  +++  +    +     
Sbjct: 298 PIFHDPISEKITAMAGHTISLNC--SAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADG 355

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +  L+  D+G Y C A +A G  E    L V
Sbjct: 356 MLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 389



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYI-NGVELKMGSRFRTTHDFG 2564
            EKPIF   ++       G              PSL   W + NG +L+ G + +  +   
Sbjct: 296  EKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSL--VWVLPNGTDLQSGQQLQRFYHKA 353

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAG 2590
               L I+ + + DAG Y C A N AG
Sbjct: 354  DGMLHISGLSSVDAGAYRCVARNAAG 379



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 5/125 (4%)

Query: 1293 DAARRTKQVREDITVMQAPQFSRALHN-IETVEGTNVHLECRLQPVGDQTMRVEWFC-NG 1350
            +AA  T+++   + V   P+ S+  HN +  + G  + L C   P G    R  W   NG
Sbjct: 376  NAAGHTERL-VSLKVGLKPEASKQYHNLVSIINGETLKLPCT--PPGAGQGRFSWTLPNG 432

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
              ++           D   L +      D G Y C+   + G +VTS  + VIA    I 
Sbjct: 433  MHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRIT 492

Query: 1411 ESQHP 1415
                P
Sbjct: 493  SEPTP 497



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)

Query: 1736 PVGDPKLRVEW-LRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
            P G  + R  W L NG+ +E    L  +       L ++  +  D GTY CR   E G +
Sbjct: 417  PPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPS 476

Query: 1795 VTSSTLFV 1802
            VTS  + V
Sbjct: 477  VTSIPVIV 484


>AK023854-1|BAB14704.1|  442|Homo sapiens .117).  protein.
          Length = 442

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 91/379 (24%), Positives = 157/379 (41%), Gaps = 37/379 (9%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            E   E  P ++WY++   ++ S    +     +  L++     ED   F  V +    +A
Sbjct: 3    ELSREDAP-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEF--VCDAGDDSA 59

Query: 4493 KCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGK 4552
              +  +    +R      IV P+      +        +R +    G++   V W K+G 
Sbjct: 60   FFTVTVTAPPER------IVHPAARSLDLHFGAPGRVELRCEVAPAGSQ---VRWYKDGL 110

Query: 4553 KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
            +V+     ++  E  T TL +  A P+D+G+Y C       E R +A   ++      +P
Sbjct: 111  EVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVC-------ETRHEA---ITFNVILAEP 160

Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672
              Q  A    P    PL    VA G+ +  SC++     P V W      ++  +  ++ 
Sbjct: 161  PVQFLALETTPS---PL---CVAPGEPVVLSCELSRAGAPVV-WSHNGGPVQEGEGLELH 213

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
                   L I  A P   G Y C +  + G  +++  ++V +P     +  LTPL    V
Sbjct: 214  AEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPLLVKLVSDLTPL---TV 270

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
            +EG  A F+ ++ S     + WLR GA++   P  +M   G++ +L +      D GT T
Sbjct: 271  HEGDDATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVT 329

Query: 4793 CRATTAAGQVETSAKLVVK 4811
             R    AG   TSA+L V+
Sbjct: 330  LR----AGSTATSARLHVR 344



 Score = 52.0 bits (119), Expect = 5e-05
 Identities = 44/177 (24%), Positives = 72/177 (40%), Gaps = 10/177 (5%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G+     C ++    P V W  N   +++    ++   E     L I     + +G+
Sbjct: 176 VAPGEPVVLSCELSRAGAP-VVWSHNGGPVQEGEGLELHA-EGPRRVLCIQAAGPAHAGL 233

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TC +    G  +    + V E   V   K V   + L V EG+        V  P   +
Sbjct: 234 YTCQSGAAPGAPSLSFTVQVAEPLLV---KLVSDLTPLTVHEGDDATFRCE-VSPPDADV 289

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           TW ++G  + P P++ +  +G +  L +   +  DA     T    AGSTAT ARL+
Sbjct: 290 TWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAG----TVTLRAGSTATSARLH 342



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 78/356 (21%), Positives = 132/356 (37%), Gaps = 37/356 (10%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++WY++   ++ S   Q+        L +     ED+  +  V E R      + N+++ 
Sbjct: 103  VRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEY--VCETRHEAI--TFNVILA 158

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            E   Q       PS       + V  G+ V L  +++      V W  NG  VQ     +
Sbjct: 159  EPPVQFLALETTPS------PLCVAPGEPVVLSCELSRAGA-PVVWSHNGGPVQEGEGLE 211

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
            +  E     L I  A P  +G Y C +  + G          SL  T    +P       
Sbjct: 212  LHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAP--------SLSFTVQVAEPLLV---- 259

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
              +++  L    V EG    F C+ V  P   V W +   ++ P    +M++      L 
Sbjct: 260  --KLVSDLTPLTVHEGDDATFRCE-VSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILT 316

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            +      D G         AG    +A+L V + +    L  L  L+D+   EGQ    +
Sbjct: 317  LRGCQLGDAGTVTL----RAGSTATSARLHVRETE----LLFLRRLQDVRAEEGQDVCLE 368

Query: 4742 TQITSKIKPT--IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
             + T ++     ++W+R G  +P      M  +G+   L I      D GT+ C +
Sbjct: 369  ME-TGRVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCES 423



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 50/181 (27%), Positives = 74/181 (40%), Gaps = 16/181 (8%)

Query: 392 PQFVKVCQDRD---VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           P  VK+  D     V EG    F C V+  P  +VTW  N   +      ++  N S + 
Sbjct: 256 PLLVKLVSDLTPLTVHEGDDATFRCEVSP-PDADVTWLRNGAVVTPGPQVEMAQNGS-SR 313

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508
            L +    L D+G VT     ++G TA   RL+V E E +    F+ R   +   EG+ V
Sbjct: 314 ILTLRGCQLGDAGTVTL----RAGSTATSARLHVRETELL----FLRRLQDVRAEEGQDV 365

Query: 509 VLNARA--VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            L      VG     + W + G P+  +  L +  DG    L I     +D   Y C + 
Sbjct: 366 CLEMETGRVGA-AGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESH 424

Query: 567 N 567
           +
Sbjct: 425 H 425



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 36/158 (22%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C ++    P V W+ +  ++ +     +L  +     L++      D G   C A + S 
Sbjct: 2   CELSREDAP-VRWYKDGLEVEES-EALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDS- 58

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT-PRITWQKDGVPI 531
             AF         E++V P       +L++  G P  +  R    P   ++ W KDG+ +
Sbjct: 59  --AFFTVTVTAPPERIVHPAA----RSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEV 112

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             +  L++  +G   TL +P A+  DA  Y C  ++ A
Sbjct: 113 EASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEA 150



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 3/88 (3%)

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            TTPS L ++        C L   + +   V W HNG P+  G  ++   +    +L I  
Sbjct: 169  TTPSPLCVAPGEPVVLSCEL---SRAGAPVVWSHNGGPVQEGEGLELHAEGPRRVLCIQA 225

Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                 AGLYTC++    G  ++S  +QV
Sbjct: 226  AGPAHAGLYTCQSGAAPGAPSLSFTVQV 253



 Score = 38.7 bits (86), Expect = 0.51
 Identities = 36/169 (21%), Positives = 63/169 (37%), Gaps = 13/169 (7%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + EG  A +   + P       + W  NG  +    ++         +L + G +  D+G
Sbjct: 270  VHEGDDATFRCEVSPPDAD---VTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAG 326

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
            T + RA    G    S +L      +  +  F   +Q++   ++GQ    E     V   
Sbjct: 327  TVTLRA----GSTATSARLHV----RETELLFLRRLQDVRA-EEGQDVCLEMETGRVGAA 377

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
               + W   GQP+ H +R+    D     L I      D G Y C +++
Sbjct: 378  G-AVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHH 425



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V+VA     + ++ L  P  + EG  A + C + P   P+  V W  NG V+  G +   
Sbjct: 251  VQVAEPLLVKLVSDLT-PLTVHEGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQVEM 306

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            + +     L +      D+G  T +A    G   +S RL+V+  E
Sbjct: 307  AQNGSSRILTLRGCQLGDAGTVTLRA----GSTATSARLHVRETE 347



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 15/48 (31%), Positives = 26/48 (54%)

Query: 1743 RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            +V W ++G+ +EAS+ L    +     L + +  PED+G Y C   +E
Sbjct: 102  QVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHE 149



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 9/102 (8%)

Query: 1172 ISKSKPVFVQPLSNPPP--VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            +  ++P+ V+ +S+  P  V EG +    C + P   P   V W  NG  VT G + +  
Sbjct: 251  VQVAEPLLVKLVSDLTPLTVHEGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQVEMA 307

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             +     L +      D G  T+RA    GS  TSA + V E
Sbjct: 308  QNGSSRILTLRGCQLGDAGTVTLRA----GSTATSARLHVRE 345



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQA 1387
            V L C + P G Q   V W+ +G  ++     +   E     L L    PED+G Y C+ 
Sbjct: 90   VELRCEVAPAGSQ---VRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCET 146

Query: 1388 TNQ 1390
             ++
Sbjct: 147  RHE 149



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
           + EG DA F+ ++S  P   VTW +NG  +    + E+    +   L +R  Q  D+G  
Sbjct: 270 VHEGDDATFRCEVSP-PDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTV 328

Query: 337 TLLA 340
           TL A
Sbjct: 329 TLRA 332



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
            +F   ++D+R  E Q    E     VG     V W+R G P+   +RL+   D     L 
Sbjct: 349  LFLRRLQDVRAEEGQDVCLEMETGRVGAAGA-VRWVRGGQPLPHDSRLSMAQDGHIHRLF 407

Query: 1772 MKYVNPEDSGTYTCRA 1787
            +  V   D GTY C +
Sbjct: 408  IHGVILADQGTYGCES 423



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 45/190 (23%), Positives = 68/190 (35%), Gaps = 17/190 (8%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            + P  V E + A F  E    P   + W R    +   P  ++    +  IL +R   + 
Sbjct: 265  LTPLTVHEGDDATFRCEVS-PPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLG 323

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D    A     R G+   SA L V E             F    Q+V    GQ V L+ +
Sbjct: 324  D----AGTVTLRAGSTATSARLHVRETELL---------FLRRLQDVRAEEGQDVCLEME 370

Query: 4537 VTGTKPID-VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
                     V W++ G+ +  D R  + ++   + L I      D G Y C + +    A
Sbjct: 371  TGRVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLA 430

Query: 4596 RCDA--ECVV 4603
            R     EC V
Sbjct: 431  RLSVRRECPV 440



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 32/117 (27%), Positives = 46/117 (39%), Gaps = 9/117 (7%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            + V EG    F C V P   P   + W  NG     G +V    +     L +      D
Sbjct: 268  LTVHEGDDATFRCEVSP---PDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGD 324

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLES-QLPQGMSGEKI-KELERGRISDA 3819
            AG  T RA    GS  T+A++       + L   Q  +   G+ +  E+E GR+  A
Sbjct: 325  AGTVTLRA----GSTATSARLHVRETELLFLRRLQDVRAEEGQDVCLEMETGRVGAA 377


>AF531872-1|AAN04866.1|  816|Homo sapiens transmembrane receptor
            precursor PTK7-5 protein.
          Length = 816

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 87/336 (25%), Positives = 134/336 (39%), Gaps = 30/336 (8%)

Query: 4480 VFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
            V A +AE+  G   C +ANL  + ++         PS+    Q+  +  G+   LD    
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQ 436

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
             T    V W +N   +  D R ++ + +GT  +  +E Y  D   Y C++   AG     
Sbjct: 437  ATPKPTVVWYRNQMLISEDSRFEVFK-NGTLRINSVEVY--DGTWYRCMSSTPAGSIEAQ 493

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            A   V L   K  P PQ      P + +E  K+  V         C   G+  PT++W +
Sbjct: 494  ARVQV-LEKLKFTPPPQ------PQQCMEFDKEATVP--------CSATGREKPTIKWER 538

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA-GRVTVAAKLKVTQPDQ 4717
             D    P        T +  TL  +    +D G+Y C+A N   G++    +L V     
Sbjct: 539  ADGSSLPEWV-----TDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFIT 593

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777
                P  T      VY+G  A  + +     KP IQW  +  ++  T     +H   N  
Sbjct: 594  FKVEPERT-----TVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGS 648

Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            L+I +   ED+G +TC A  +     T A L V  K
Sbjct: 649  LVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 92/414 (22%), Positives = 156/414 (37%), Gaps = 50/414 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-IL 4468
            P +         +    Q       DG P P  +W+R+  P+ +      HT S+K   L
Sbjct: 128  PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQ--SNHTVSSKERNL 185

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             +R    E S +++  A +  G A  S N  +          ++ P      Q+V V   
Sbjct: 186  TLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAP------QDVVVARY 239

Query: 4529 QLVRLDTKVTGTKPIDVYWL------KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            +      + +   P  + WL         +   P +R   +  +G  +LL+ +  P+++G
Sbjct: 240  EEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANG--SLLLTQVRPRNAG 297

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y C+     G      E  + L   +D P            + EP   ++   G     
Sbjct: 298  IYRCIGQGQRGPP-IILEATLHLAEIEDMP------------LFEP---RVFTAGSEERV 341

Query: 4643 SC-KIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            +C    G P P+V W + G +L    + +Q       + L ++     D G Y C A N 
Sbjct: 342  TCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKG-----HELVLANIAESDAGVYTCHAANL 396

Query: 4701 AGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
            AG+      + V        +P+ L   +D  + EG+P        +  KPT+ W R   
Sbjct: 397  AGQRRQDVNITVA------TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQM 450

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            LI E   F++     N  L I +    D   + C ++T AG +E  A++ V  K
Sbjct: 451  LISEDSRFEVF---KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 48/181 (26%), Positives = 80/181 (44%), Gaps = 14/181 (7%)

Query: 399 QDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457
           + R  T G   R  C    G P P V W      +R   + ++   + G H L++ N+  
Sbjct: 329 EPRVFTAGSEERVTCLPPKGLPEPSVWW--EHAGVRLPTHGRVY--QKG-HELVLANIAE 383

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           SD+GV TC A N +G+      + V        P ++++     + EG+P  L+     T
Sbjct: 384 SDAGVYTCHAANLAGQRRQDVNITV-----ATVPSWLKKPQDSQLEEGKPGYLDCLTQAT 438

Query: 518 PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
           P P + W ++ + I  +    +  +G   TL I   +  D  WY+C +   AGS   +AR
Sbjct: 439 PKPTVVWYRNQMLISEDSRFEVFKNG---TLRINSVEVYDGTWYRCMSSTPAGSIEAQAR 495

Query: 578 L 578
           +
Sbjct: 496 V 496



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 76/327 (23%), Positives = 125/327 (38%), Gaps = 53/327 (16%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D ++   + P   +KP++S+L+EG            P+P V W++N   +   ++ E+  
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVF- 461

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
              + TLR+ + +  D   Y  ++  P G I            E+  + Q  + +  T  
Sbjct: 462 --KNGTLRINSVEVYDGTWYRCMSSTPAGSI------------EAQARVQVLEKLKFTPP 507

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            + ++ +E  ++A  P                    C  TGR  P + W   D     ++
Sbjct: 508 PQPQQCMEFDKEATVP--------------------CSATGREKPTIKWERADGSSLPEW 547

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARN-KSGETAFQCRLNVIEKEQVVAPKFVE 495
               + + +G   L    VT  D+G  TC+A N   G+     +L V      V   F  
Sbjct: 548 ----VTDNAG--TLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTV-----AVFITFKV 596

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQ-KDGV--PIIPNPELRIHTDGGASTLDIPR 552
                 V +G   +L   A G P P I W+ KD +  P    P + I  +G   +L I  
Sbjct: 597 EPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNG---SLVIHD 653

Query: 553 AKASDAAWYQCTAQNVAGSTATRARLY 579
               D+  Y C A N      T A LY
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLY 680



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 70/310 (22%), Positives = 120/310 (38%), Gaps = 44/310 (14%)

Query: 266 PKIAQKPRN-SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P + + P + +++Q       +  + G+PRP   WF++G  L +   +  +++     L 
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERN-LT 186

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +R      SG Y+  A +  G   +S    +    ES+                   R+ 
Sbjct: 187 LRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFA------------------RV- 227

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR---QIRDDYNHKIL 441
                LAPQ V V +  +        F C+ + +P P + W   D      R    H   
Sbjct: 228 ----VLAPQDVVVARYEEAM------FHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRR 277

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTL 500
                N +L++T V   ++G+  C+ + + G     +  L++ E E +  P F  R  T 
Sbjct: 278 ATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM--PLFEPRVFTA 335

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
                E  V      G P P + W+  GV +  +   R++  G    L +     SDA  
Sbjct: 336 G---SEERVTCLPPKGLPEPSVWWEHAGVRLPTHG--RVYQKG--HELVLANIAESDAGV 388

Query: 561 YQCTAQNVAG 570
           Y C A N+AG
Sbjct: 389 YTCHAANLAG 398



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 86/392 (21%), Positives = 155/392 (39%), Gaps = 45/392 (11%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF-VEDSAVFAAVA-E 4486
            R EVE  G P+  + W  +  P++++       F+  S L    V  ++DS  F  VA +
Sbjct: 52   RCEVEAPG-PVH-VYWLLDGAPVQDTE----RRFAQGSSLSFAAVDRLQDSGTFQCVARD 105

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            +  G    SAN     K  +  G +V       A    +     V L   + G       
Sbjct: 106  DVTGEEARSANASFNIKWIEA-GPVV---LKHPASEAEIQPQTQVTLRCHIDGHPRPTYQ 161

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W ++G  +     N  +       L +  A P+ SG Y C A ++ G+A       +S+ 
Sbjct: 162  WFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSI- 219

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK--LIK 4664
                       A  +   ++   +D +VA  +   F C+   +P P++QW   D+  +  
Sbjct: 220  -----------ADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITN 268

Query: 4665 PSK--YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLKVTQPDQADNL 4721
             S+  + + +      +L +++  P + G Y+C+     G  + + A L + +    +++
Sbjct: 269  RSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAE---IEDM 325

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSK--IKPTIQWLREGALIPETPD-FQMIHEGNNAVL 4778
            P   P     V+     +  T +  K   +P++ W   G  +P     +Q  HE     L
Sbjct: 326  PLFEPR----VFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHE-----L 376

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            ++ N  E D G +TC A   AGQ      + V
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITV 408



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 11/133 (8%)

Query: 4414 TKKMQPCR--VFEHEQARFEVEFDGEPLPLIKWYREN---FPIKNSPDFQIHTFSTKSIL 4468
            T K++P R  V++   A  + E  G+P PLI+W  ++    P K  P  ++H F   S L
Sbjct: 593  TFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP--RMHIFQNGS-L 649

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK--RRQGRGGIVPPSFTLTAQNVNVT 4526
            +I  V  EDS  +  +A N        A L V +K    +  G   PP + +  Q + ++
Sbjct: 650  VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKM-IQTIGLS 708

Query: 4527 SGQLVRLDTKVTG 4539
             G  V     V G
Sbjct: 709  VGAAVAYIIAVLG 721



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 40/183 (21%), Positives = 66/183 (36%), Gaps = 7/183 (3%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
           F+K    +D  +G+     C V       V W ++   ++D    +     S + A +  
Sbjct: 34  FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDT-ERRFAQGSSLSFAAVDR 92

Query: 454 NVTLSDSGVVTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVER-FSTLNVREGEPVVLN 511
              L DSG   CVAR+  +GE A     +   K     P  ++   S   ++    V L 
Sbjct: 93  ---LQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               G P P   W +DG P + + +           L +  A    +  Y C A +  G 
Sbjct: 150 CHIDGHPRPTYQWFRDGTP-LSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQ 208

Query: 572 TAT 574
             +
Sbjct: 209 ACS 211



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/68 (35%), Positives = 33/68 (48%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDPK  ++W      ++ +     MH F   +L +  V PEDSG YTC A N      T 
Sbjct: 617  GDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTE 676

Query: 1798 STLFVQSK 1805
            + L+V  K
Sbjct: 677  APLYVVDK 684



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 4/67 (5%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE-QTGDVSLLIKQIGPGDEGE 143
           QG  A  + + +G+P P++ W + K  +++  K   R +  Q G  SL+I  + P D G 
Sbjct: 605 QGHTALLQCEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNG--SLVIHDVAPEDSGR 661

Query: 144 YTCTARN 150
           YTC A N
Sbjct: 662 YTCIAGN 668



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + +G TA   C     GDP   ++W   +++++ +    + H F   S+ I  V  ED G
Sbjct: 603  VYQGHTALLQCEA--QGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG 660

Query: 2448 VYMCRASN 2455
             Y C A N
Sbjct: 661  RYTCIAGN 668



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 6/90 (6%)

Query: 3982 QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKP-LLHKNRFTP-IYDFGYVAMNFGWVY 4039
            +T++ +  T   +C+    GDP   ++W   GK  +L   +  P ++ F   ++    V 
Sbjct: 600  RTTVYQGHTALLQCEAQ--GDPKPLIQW--KGKDRILDPTKLGPRMHIFQNGSLVIHDVA 655

Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            PEDSG Y C A N   +  T+A +    KP
Sbjct: 656  PEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            A LA  RR  V  T    P W+     + QL EG+  +L+   +    P   + WY N  
Sbjct: 394  ANLAGQRRQDVNITVATVPSWLKK-PQDSQLEEGKPGYLDCLTQATPKPT--VVWYRNQM 450

Query: 2953 VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            ++ + SRF++  + G + ++ V+VY  D   Y C +    G     + V    K
Sbjct: 451  LISEDSRFEVFKN-GTLRINSVEVY--DGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V +G      C   G P P + W   DR I D       ++   N +L+I +V   DSG 
Sbjct: 603 VYQGHTALLQCEAQGDPKPLIQWKGKDR-ILDPTKLGPRMHIFQNGSLVIHDVAPEDSGR 661

Query: 463 VTCVARNKSGETAFQCRLNVIEK 485
            TC+A N       +  L V++K
Sbjct: 662 YTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 62/285 (21%), Positives = 99/285 (34%), Gaps = 18/285 (6%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E  P + +     A             + G+P P   W R   PL +       +   + 
Sbjct: 125 EAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQS---NHTVSSK 181

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS----VYIQPEGXXXXXXXXXXXXXYRHVS 183
           + +L ++  GP   G Y+C A + +G+A  S    + I  E               R+  
Sbjct: 182 ERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARY-E 240

Query: 184 ETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
           E + H  +  Q   + Q     +   TN +         V      LL +V  R +   R
Sbjct: 241 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR 300

Query: 244 YVGESD--VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWF 300
            +G+      I  E    L  +    + + PR      G++ +   +   G P P V W 
Sbjct: 301 CIGQGQRGPPIILEATLHLAEIEDMPLFE-PR--VFTAGSEERVTCLPPKGLPEPSVWWE 357

Query: 301 KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             G RL     H  +    H  L + N  +SD+G YT  A N  G
Sbjct: 358 HAGVRL---PTHGRVYQKGH-ELVLANIAESDAGVYTCHAANLAG 398



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E  GD    ++W    R ++ +        F   +L I  V   D+G YTC A N+    
Sbjct: 614  EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 994  TTSANLTIVTKKDIIAESQHPG 1015
             T A L +V  K +  ES+ PG
Sbjct: 674  HTEAPLYVV-DKPVPEESEGPG 694



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/77 (27%), Positives = 37/77 (48%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           E  GDP   I+W    + ++ +     +  F   SL +  +  +DSG YTC A ++  + 
Sbjct: 614 EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 721 ETKAVLHVTPRATIERT 737
            T+A L+V  +   E +
Sbjct: 674 HTEAPLYVVDKPVPEES 690



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 17/125 (13%)

Query: 1288 IQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHL-----ECRLQPVGDQTM 1342
            +  L+D+       R+D+T  +A + + A  NI+ +E   V L     E  +QP    T+
Sbjct: 90   VDRLQDSGTFQCVARDDVTGEEA-RSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTL 148

Query: 1343 RV----------EWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            R           +WF +G P+  G         +   L L    PE SG+Y+C A +  G
Sbjct: 149  RCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFG 207

Query: 1393 EAVTS 1397
            +A +S
Sbjct: 208  QACSS 212



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 11/128 (8%)

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
            R  C + PK  P+  + W   G  LP+  R   VY  G   L +  +   D+G Y C A 
Sbjct: 340  RVTC-LPPKGLPEPSVWWEHAGVRLPTHGR---VYQKGH-ELVLANIAESDAGVYTCHAA 394

Query: 3908 NDFGEDFTKATISCKKLPDIILQ---NQVPRGMK-RSEALTQM--EATIKKYTSEVYLTE 3961
            N  G+      I+   +P  + +   +Q+  G     + LTQ   + T+  Y +++ ++E
Sbjct: 395  NLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISE 454

Query: 3962 DDLYDVDK 3969
            D  ++V K
Sbjct: 455  DSRFEVFK 462



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 1/95 (1%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q E + DP   I+W    ++L+          F   +L + DV   DSG YTC A N   
Sbjct: 612  QCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNL 3028
               T + +Y   K  + E ++ P      + IQ +
Sbjct: 672  IKHTEAPLYVVDKP-VPEESEGPGSPPPYKMIQTI 705



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 5/62 (8%)

Query: 1738 GDPKLRVEWLRNGVPIE--ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G P+   +W R+G P+    SN   +  +     L ++   PE SG Y+C A +  G+A 
Sbjct: 154  GHPRPTYQWFRDGTPLSDGQSNHTVSSKERN---LTLRPAGPEHSGLYSCCAHSAFGQAC 210

Query: 1796 TS 1797
            +S
Sbjct: 211  SS 212



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGK---PIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
            +G    L+C  Q  GD    ++W    +   P K G R    + F   +L +  V PEDS
Sbjct: 605  QGHTALLQCEAQ--GDPKPLIQWKGKDRILDPTKLGPRM---HIFQNGSLVIHDVAPEDS 659

Query: 1381 GVYTCQATNQLGEAVTSCALRVIAK 1405
            G YTC A N      T   L V+ K
Sbjct: 660  GRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++  P+   H  S  ++     V L   ++    P    +WF++G  L+ G +   T   
Sbjct: 124  IEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTY--QWFRDGTPLSDG-QSNHTVSS 180

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                L++     + SG+Y+C A +  G+A S+ +  +
Sbjct: 181  KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +W +DG P+       T  +     LT++      +G Y+C A++A GQA +S N T+
Sbjct: 161  QWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217


>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
            precursor PTK7-1 protein.
          Length = 1070

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 87/336 (25%), Positives = 134/336 (39%), Gaps = 30/336 (8%)

Query: 4480 VFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
            V A +AE+  G   C +ANL  + ++         PS+    Q+  +  G+   LD    
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQ 436

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
             T    V W +N   +  D R ++ + +GT  +  +E Y  D   Y C++   AG     
Sbjct: 437  ATPKPTVVWYRNQMLISEDSRFEVFK-NGTLRINSVEVY--DGTWYRCMSSTPAGSIEAQ 493

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            A   V L   K  P PQ      P + +E  K+  V         C   G+  PT++W +
Sbjct: 494  ARVQV-LEKLKFTPPPQ------PQQCMEFDKEATVP--------CSATGREKPTIKWER 538

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA-GRVTVAAKLKVTQPDQ 4717
             D    P        T +  TL  +    +D G+Y C+A N   G++    +L V     
Sbjct: 539  ADGSSLPEWV-----TDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFIT 593

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777
                P  T      VY+G  A  + +     KP IQW  +  ++  T     +H   N  
Sbjct: 594  FKVEPERT-----TVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGS 648

Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            L+I +   ED+G +TC A  +     T A L V  K
Sbjct: 649  LVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 92/414 (22%), Positives = 156/414 (37%), Gaps = 50/414 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-IL 4468
            P +         +    Q       DG P P  +W+R+  P+ +      HT S+K   L
Sbjct: 128  PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQ--SNHTVSSKERNL 185

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             +R    E S +++  A +  G A  S N  +          ++ P      Q+V V   
Sbjct: 186  TLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAP------QDVVVARY 239

Query: 4529 QLVRLDTKVTGTKPIDVYWL------KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            +      + +   P  + WL         +   P +R   +  +G  +LL+ +  P+++G
Sbjct: 240  EEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANG--SLLLTQVRPRNAG 297

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y C+     G      E  + L   +D P            + EP   ++   G     
Sbjct: 298  IYRCIGQGQRGPP-IILEATLHLAEIEDMP------------LFEP---RVFTAGSEERV 341

Query: 4643 SC-KIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            +C    G P P+V W + G +L    + +Q       + L ++     D G Y C A N 
Sbjct: 342  TCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKG-----HELVLANIAESDAGVYTCHAANL 396

Query: 4701 AGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
            AG+      + V        +P+ L   +D  + EG+P        +  KPT+ W R   
Sbjct: 397  AGQRRQDVNITVA------TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQM 450

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            LI E   F++     N  L I +    D   + C ++T AG +E  A++ V  K
Sbjct: 451  LISEDSRFEVF---KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 48/181 (26%), Positives = 80/181 (44%), Gaps = 14/181 (7%)

Query: 399 QDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457
           + R  T G   R  C    G P P V W      +R   + ++   + G H L++ N+  
Sbjct: 329 EPRVFTAGSEERVTCLPPKGLPEPSVWW--EHAGVRLPTHGRVY--QKG-HELVLANIAE 383

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           SD+GV TC A N +G+      + V        P ++++     + EG+P  L+     T
Sbjct: 384 SDAGVYTCHAANLAGQRRQDVNITV-----ATVPSWLKKPQDSQLEEGKPGYLDCLTQAT 438

Query: 518 PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
           P P + W ++ + I  +    +  +G   TL I   +  D  WY+C +   AGS   +AR
Sbjct: 439 PKPTVVWYRNQMLISEDSRFEVFKNG---TLRINSVEVYDGTWYRCMSSTPAGSIEAQAR 495

Query: 578 L 578
           +
Sbjct: 496 V 496



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 76/327 (23%), Positives = 125/327 (38%), Gaps = 53/327 (16%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D ++   + P   +KP++S+L+EG            P+P V W++N   +   ++ E+  
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVF- 461

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
              + TLR+ + +  D   Y  ++  P G I            E+  + Q  + +  T  
Sbjct: 462 --KNGTLRINSVEVYDGTWYRCMSSTPAGSI------------EAQARVQVLEKLKFTPP 507

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            + ++ +E  ++A  P                    C  TGR  P + W   D     ++
Sbjct: 508 PQPQQCMEFDKEATVP--------------------CSATGREKPTIKWERADGSSLPEW 547

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARN-KSGETAFQCRLNVIEKEQVVAPKFVE 495
               + + +G   L    VT  D+G  TC+A N   G+     +L V      V   F  
Sbjct: 548 ----VTDNAG--TLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTV-----AVFITFKV 596

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQ-KDGV--PIIPNPELRIHTDGGASTLDIPR 552
                 V +G   +L   A G P P I W+ KD +  P    P + I  +G   +L I  
Sbjct: 597 EPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNG---SLVIHD 653

Query: 553 AKASDAAWYQCTAQNVAGSTATRARLY 579
               D+  Y C A N      T A LY
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLY 680



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 70/310 (22%), Positives = 120/310 (38%), Gaps = 44/310 (14%)

Query: 266 PKIAQKPRN-SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P + + P + +++Q       +  + G+PRP   WF++G  L +   +  +++     L 
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERN-LT 186

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +R      SG Y+  A +  G   +S    +    ES+                   R+ 
Sbjct: 187 LRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFA------------------RV- 227

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR---QIRDDYNHKIL 441
                LAPQ V V +  +        F C+ + +P P + W   D      R    H   
Sbjct: 228 ----VLAPQDVVVARYEEAM------FHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRR 277

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTL 500
                N +L++T V   ++G+  C+ + + G     +  L++ E E +  P F  R  T 
Sbjct: 278 ATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM--PLFEPRVFTA 335

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
                E  V      G P P + W+  GV +  +   R++  G    L +     SDA  
Sbjct: 336 G---SEERVTCLPPKGLPEPSVWWEHAGVRLPTHG--RVYQKG--HELVLANIAESDAGV 388

Query: 561 YQCTAQNVAG 570
           Y C A N+AG
Sbjct: 389 YTCHAANLAG 398



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 86/392 (21%), Positives = 155/392 (39%), Gaps = 45/392 (11%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF-VEDSAVFAAVA-E 4486
            R EVE  G P+  + W  +  P++++       F+  S L    V  ++DS  F  VA +
Sbjct: 52   RCEVEAPG-PVH-VYWLLDGAPVQDTE----RRFAQGSSLSFAAVDRLQDSGTFQCVARD 105

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            +  G    SAN     K  +  G +V       A    +     V L   + G       
Sbjct: 106  DVTGEEARSANASFNIKWIEA-GPVV---LKHPASEAEIQPQTQVTLRCHIDGHPRPTYQ 161

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W ++G  +     N  +       L +  A P+ SG Y C A ++ G+A       +S+ 
Sbjct: 162  WFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSI- 219

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK--LIK 4664
                       A  +   ++   +D +VA  +   F C+   +P P++QW   D+  +  
Sbjct: 220  -----------ADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITN 268

Query: 4665 PSK--YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLKVTQPDQADNL 4721
             S+  + + +      +L +++  P + G Y+C+     G  + + A L + +    +++
Sbjct: 269  RSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAE---IEDM 325

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSK--IKPTIQWLREGALIPETPD-FQMIHEGNNAVL 4778
            P   P     V+     +  T +  K   +P++ W   G  +P     +Q  HE     L
Sbjct: 326  PLFEPR----VFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHE-----L 376

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            ++ N  E D G +TC A   AGQ      + V
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITV 408



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 11/133 (8%)

Query: 4414 TKKMQPCR--VFEHEQARFEVEFDGEPLPLIKWYREN---FPIKNSPDFQIHTFSTKSIL 4468
            T K++P R  V++   A  + E  G+P PLI+W  ++    P K  P  ++H F   S L
Sbjct: 593  TFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP--RMHIFQNGS-L 649

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK--RRQGRGGIVPPSFTLTAQNVNVT 4526
            +I  V  EDS  +  +A N        A L V +K    +  G   PP + +  Q + ++
Sbjct: 650  VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKM-IQTIGLS 708

Query: 4527 SGQLVRLDTKVTG 4539
             G  V     V G
Sbjct: 709  VGAAVAYIIAVLG 721



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 40/183 (21%), Positives = 66/183 (36%), Gaps = 7/183 (3%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
           F+K    +D  +G+     C V       V W ++   ++D    +     S + A +  
Sbjct: 34  FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDT-ERRFAQGSSLSFAAVDR 92

Query: 454 NVTLSDSGVVTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVER-FSTLNVREGEPVVLN 511
              L DSG   CVAR+  +GE A     +   K     P  ++   S   ++    V L 
Sbjct: 93  ---LQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               G P P   W +DG P + + +           L +  A    +  Y C A +  G 
Sbjct: 150 CHIDGHPRPTYQWFRDGTP-LSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQ 208

Query: 572 TAT 574
             +
Sbjct: 209 ACS 211



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/68 (35%), Positives = 33/68 (48%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDPK  ++W      ++ +     MH F   +L +  V PEDSG YTC A N      T 
Sbjct: 617  GDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTE 676

Query: 1798 STLFVQSK 1805
            + L+V  K
Sbjct: 677  APLYVVDK 684



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 4/67 (5%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE-QTGDVSLLIKQIGPGDEGE 143
           QG  A  + + +G+P P++ W + K  +++  K   R +  Q G  SL+I  + P D G 
Sbjct: 605 QGHTALLQCEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNG--SLVIHDVAPEDSGR 661

Query: 144 YTCTARN 150
           YTC A N
Sbjct: 662 YTCIAGN 668



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + +G TA   C     GDP   ++W   +++++ +    + H F   S+ I  V  ED G
Sbjct: 603  VYQGHTALLQCEA--QGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG 660

Query: 2448 VYMCRASN 2455
             Y C A N
Sbjct: 661  RYTCIAGN 668



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 6/90 (6%)

Query: 3982 QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKP-LLHKNRFTP-IYDFGYVAMNFGWVY 4039
            +T++ +  T   +C+    GDP   ++W   GK  +L   +  P ++ F   ++    V 
Sbjct: 600  RTTVYQGHTALLQCEAQ--GDPKPLIQW--KGKDRILDPTKLGPRMHIFQNGSLVIHDVA 655

Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            PEDSG Y C A N   +  T+A +    KP
Sbjct: 656  PEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            A LA  RR  V  T    P W+     + QL EG+  +L+   +    P   + WY N  
Sbjct: 394  ANLAGQRRQDVNITVATVPSWLKK-PQDSQLEEGKPGYLDCLTQATPKPT--VVWYRNQM 450

Query: 2953 VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            ++ + SRF++  + G + ++ V+VY  D   Y C +    G     + V    K
Sbjct: 451  LISEDSRFEVFKN-GTLRINSVEVY--DGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V +G      C   G P P + W   DR I D       ++   N +L+I +V   DSG 
Sbjct: 603 VYQGHTALLQCEAQGDPKPLIQWKGKDR-ILDPTKLGPRMHIFQNGSLVIHDVAPEDSGR 661

Query: 463 VTCVARNKSGETAFQCRLNVIEK 485
            TC+A N       +  L V++K
Sbjct: 662 YTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 62/285 (21%), Positives = 99/285 (34%), Gaps = 18/285 (6%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E  P + +     A             + G+P P   W R   PL +       +   + 
Sbjct: 125 EAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQS---NHTVSSK 181

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS----VYIQPEGXXXXXXXXXXXXXYRHVS 183
           + +L ++  GP   G Y+C A + +G+A  S    + I  E               R+  
Sbjct: 182 ERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARY-E 240

Query: 184 ETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
           E + H  +  Q   + Q     +   TN +         V      LL +V  R +   R
Sbjct: 241 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR 300

Query: 244 YVGESD--VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWF 300
            +G+      I  E    L  +    + + PR      G++ +   +   G P P V W 
Sbjct: 301 CIGQGQRGPPIILEATLHLAEIEDMPLFE-PR--VFTAGSEERVTCLPPKGLPEPSVWWE 357

Query: 301 KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             G RL     H  +    H  L + N  +SD+G YT  A N  G
Sbjct: 358 HAGVRL---PTHGRVYQKGH-ELVLANIAESDAGVYTCHAANLAG 398



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E  GD    ++W    R ++ +        F   +L I  V   D+G YTC A N+    
Sbjct: 614  EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 994  TTSANLTIVTKKDIIAESQHPG 1015
             T A L +V  K +  ES+ PG
Sbjct: 674  HTEAPLYVV-DKPVPEESEGPG 694



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/77 (27%), Positives = 37/77 (48%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           E  GDP   I+W    + ++ +     +  F   SL +  +  +DSG YTC A ++  + 
Sbjct: 614 EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 721 ETKAVLHVTPRATIERT 737
            T+A L+V  +   E +
Sbjct: 674 HTEAPLYVVDKPVPEES 690



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 17/125 (13%)

Query: 1288 IQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHL-----ECRLQPVGDQTM 1342
            +  L+D+       R+D+T  +A + + A  NI+ +E   V L     E  +QP    T+
Sbjct: 90   VDRLQDSGTFQCVARDDVTGEEA-RSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTL 148

Query: 1343 RV----------EWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            R           +WF +G P+  G         +   L L    PE SG+Y+C A +  G
Sbjct: 149  RCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFG 207

Query: 1393 EAVTS 1397
            +A +S
Sbjct: 208  QACSS 212



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 11/128 (8%)

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
            R  C + PK  P+  + W   G  LP+  R   VY  G   L +  +   D+G Y C A 
Sbjct: 340  RVTC-LPPKGLPEPSVWWEHAGVRLPTHGR---VYQKGH-ELVLANIAESDAGVYTCHAA 394

Query: 3908 NDFGEDFTKATISCKKLPDIILQ---NQVPRGMK-RSEALTQM--EATIKKYTSEVYLTE 3961
            N  G+      I+   +P  + +   +Q+  G     + LTQ   + T+  Y +++ ++E
Sbjct: 395  NLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISE 454

Query: 3962 DDLYDVDK 3969
            D  ++V K
Sbjct: 455  DSRFEVFK 462



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 1/95 (1%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q E + DP   I+W    ++L+          F   +L + DV   DSG YTC A N   
Sbjct: 612  QCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNL 3028
               T + +Y   K  + E ++ P      + IQ +
Sbjct: 672  IKHTEAPLYVVDKP-VPEESEGPGSPPPYKMIQTI 705



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 5/62 (8%)

Query: 1738 GDPKLRVEWLRNGVPIE--ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G P+   +W R+G P+    SN   +  +     L ++   PE SG Y+C A +  G+A 
Sbjct: 154  GHPRPTYQWFRDGTPLSDGQSNHTVSSKERN---LTLRPAGPEHSGLYSCCAHSAFGQAC 210

Query: 1796 TS 1797
            +S
Sbjct: 211  SS 212



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGK---PIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
            +G    L+C  Q  GD    ++W    +   P K G R    + F   +L +  V PEDS
Sbjct: 605  QGHTALLQCEAQ--GDPKPLIQWKGKDRILDPTKLGPRM---HIFQNGSLVIHDVAPEDS 659

Query: 1381 GVYTCQATNQLGEAVTSCALRVIAK 1405
            G YTC A N      T   L V+ K
Sbjct: 660  GRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++  P+   H  S  ++     V L   ++    P    +WF++G  L+ G +   T   
Sbjct: 124  IEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTY--QWFRDGTPLSDG-QSNHTVSS 180

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                L++     + SG+Y+C A +  G+A S+ +  +
Sbjct: 181  KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +W +DG P+       T  +     LT++      +G Y+C A++A GQA +S N T+
Sbjct: 161  QWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217


>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
            protein.
          Length = 1070

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 87/336 (25%), Positives = 134/336 (39%), Gaps = 30/336 (8%)

Query: 4480 VFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
            V A +AE+  G   C +ANL  + ++         PS+    Q+  +  G+   LD    
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQ 436

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
             T    V W +N   +  D R ++ + +GT  +  +E Y  D   Y C++   AG     
Sbjct: 437  ATPKPTVVWYRNQMLISEDSRFEVFK-NGTLRINSVEVY--DGTWYRCMSSTPAGSIEAQ 493

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            A   V L   K  P PQ      P + +E  K+  V         C   G+  PT++W +
Sbjct: 494  ARVQV-LEKLKFTPPPQ------PQQCMEFDKEATVP--------CSATGREKPTIKWER 538

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA-GRVTVAAKLKVTQPDQ 4717
             D    P        T +  TL  +    +D G+Y C+A N   G++    +L V     
Sbjct: 539  ADGSSLPEWV-----TDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFIT 593

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777
                P  T      VY+G  A  + +     KP IQW  +  ++  T     +H   N  
Sbjct: 594  FKVEPERT-----TVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGS 648

Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            L+I +   ED+G +TC A  +     T A L V  K
Sbjct: 649  LVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 74.9 bits (176), Expect = 6e-12
 Identities = 92/414 (22%), Positives = 156/414 (37%), Gaps = 50/414 (12%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS-IL 4468
            P +         +    Q       DG P P  +W+R+  P+ +      HT S+K   L
Sbjct: 128  PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQ--SNHTVSSKERNL 185

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             +R    E S +++  A +  G A  S N  +          ++ P      Q+V V   
Sbjct: 186  TLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAP------QDVVVARY 239

Query: 4529 QLVRLDTKVTGTKPIDVYWL------KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            +      + +   P  + WL         +   P +R   +  +G  +LL+ +  P+++G
Sbjct: 240  EEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANG--SLLLTQVRPRNAG 297

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y C+     G      E  + L   +D P            + EP   ++   G     
Sbjct: 298  IYRCIGQGQRGPP-IILEATLHLAEIEDMP------------LFEP---RVFTAGSEERV 341

Query: 4643 SC-KIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            +C    G P P+V W + G +L    + +Q       + L ++     D G Y C A N 
Sbjct: 342  TCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKG-----HELVLANIAESDAGVYTCHAANL 396

Query: 4701 AGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
            AG+      + V        +P+ L   +D  + EG+P        +  KPT+ W R   
Sbjct: 397  AGQRRQDVNITVA------TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQM 450

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            LI E   F++     N  L I +    D   + C ++T AG +E  A++ V  K
Sbjct: 451  LISEDSRFEVF---KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 68.5 bits (160), Expect = 6e-10
 Identities = 48/181 (26%), Positives = 80/181 (44%), Gaps = 14/181 (7%)

Query: 399 QDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457
           + R  T G   R  C    G P P V W      +R   + ++   + G H L++ N+  
Sbjct: 329 EPRVFTAGSEERVTCLPPKGLPEPSVWW--EHAGVRLPTHGRVY--QKG-HELVLANIAE 383

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           SD+GV TC A N +G+      + V        P ++++     + EG+P  L+     T
Sbjct: 384 SDAGVYTCHAANLAGQRRQDVNITV-----ATVPSWLKKPQDSQLEEGKPGYLDCLTQAT 438

Query: 518 PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
           P P + W ++ + I  +    +  +G   TL I   +  D  WY+C +   AGS   +AR
Sbjct: 439 PKPTVVWYRNQMLISEDSRFEVFKNG---TLRINSVEVYDGTWYRCMSSTPAGSIEAQAR 495

Query: 578 L 578
           +
Sbjct: 496 V 496



 Score = 65.7 bits (153), Expect = 4e-09
 Identities = 76/327 (23%), Positives = 125/327 (38%), Gaps = 53/327 (16%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D ++   + P   +KP++S+L+EG            P+P V W++N   +   ++ E+  
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVF- 461

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
              + TLR+ + +  D   Y  ++  P G I            E+  + Q  + +  T  
Sbjct: 462 --KNGTLRINSVEVYDGTWYRCMSSTPAGSI------------EAQARVQVLEKLKFTPP 507

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            + ++ +E  ++A  P                    C  TGR  P + W   D     ++
Sbjct: 508 PQPQQCMEFDKEATVP--------------------CSATGREKPTIKWERADGSSLPEW 547

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARN-KSGETAFQCRLNVIEKEQVVAPKFVE 495
               + + +G   L    VT  D+G  TC+A N   G+     +L V      V   F  
Sbjct: 548 ----VTDNAG--TLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTV-----AVFITFKV 596

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQ-KDGV--PIIPNPELRIHTDGGASTLDIPR 552
                 V +G   +L   A G P P I W+ KD +  P    P + I  +G   +L I  
Sbjct: 597 EPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNG---SLVIHD 653

Query: 553 AKASDAAWYQCTAQNVAGSTATRARLY 579
               D+  Y C A N      T A LY
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLY 680



 Score = 57.6 bits (133), Expect = 1e-06
 Identities = 70/310 (22%), Positives = 120/310 (38%), Gaps = 44/310 (14%)

Query: 266 PKIAQKPRN-SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P + + P + +++Q       +  + G+PRP   WF++G  L +   +  +++     L 
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERN-LT 186

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           +R      SG Y+  A +  G   +S    +    ES+                   R+ 
Sbjct: 187 LRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFA------------------RV- 227

Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR---QIRDDYNHKIL 441
                LAPQ V V +  +        F C+ + +P P + W   D      R    H   
Sbjct: 228 ----VLAPQDVVVARYEEAM------FHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRR 277

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTL 500
                N +L++T V   ++G+  C+ + + G     +  L++ E E +  P F  R  T 
Sbjct: 278 ATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM--PLFEPRVFTA 335

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
                E  V      G P P + W+  GV +  +   R++  G    L +     SDA  
Sbjct: 336 G---SEERVTCLPPKGLPEPSVWWEHAGVRLPTHG--RVYQKG--HELVLANIAESDAGV 388

Query: 561 YQCTAQNVAG 570
           Y C A N+AG
Sbjct: 389 YTCHAANLAG 398



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 86/392 (21%), Positives = 155/392 (39%), Gaps = 45/392 (11%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVF-VEDSAVFAAVA-E 4486
            R EVE  G P+  + W  +  P++++       F+  S L    V  ++DS  F  VA +
Sbjct: 52   RCEVEAPG-PVH-VYWLLDGAPVQDTE----RRFAQGSSLSFAAVDRLQDSGTFQCVARD 105

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            +  G    SAN     K  +  G +V       A    +     V L   + G       
Sbjct: 106  DVTGEEARSANASFNIKWIEA-GPVV---LKHPASEAEIQPQTQVTLRCHIDGHPRPTYQ 161

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W ++G  +     N  +       L +  A P+ SG Y C A ++ G+A       +S+ 
Sbjct: 162  WFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSI- 219

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK--LIK 4664
                       A  +   ++   +D +VA  +   F C+   +P P++QW   D+  +  
Sbjct: 220  -----------ADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITN 268

Query: 4665 PSK--YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLKVTQPDQADNL 4721
             S+  + + +      +L +++  P + G Y+C+     G  + + A L + +    +++
Sbjct: 269  RSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAE---IEDM 325

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSK--IKPTIQWLREGALIPETPD-FQMIHEGNNAVL 4778
            P   P     V+     +  T +  K   +P++ W   G  +P     +Q  HE     L
Sbjct: 326  PLFEPR----VFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHE-----L 376

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            ++ N  E D G +TC A   AGQ      + V
Sbjct: 377  VLANIAESDAGVYTCHAANLAGQRRQDVNITV 408



 Score = 42.7 bits (96), Expect = 0.031
 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 11/133 (8%)

Query: 4414 TKKMQPCR--VFEHEQARFEVEFDGEPLPLIKWYREN---FPIKNSPDFQIHTFSTKSIL 4468
            T K++P R  V++   A  + E  G+P PLI+W  ++    P K  P  ++H F   S L
Sbjct: 593  TFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP--RMHIFQNGS-L 649

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK--RRQGRGGIVPPSFTLTAQNVNVT 4526
            +I  V  EDS  +  +A N        A L V +K    +  G   PP + +  Q + ++
Sbjct: 650  VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKM-IQTIGLS 708

Query: 4527 SGQLVRLDTKVTG 4539
             G  V     V G
Sbjct: 709  VGAAVAYIIAVLG 721



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 40/183 (21%), Positives = 66/183 (36%), Gaps = 7/183 (3%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
           F+K    +D  +G+     C V       V W ++   ++D    +     S + A +  
Sbjct: 34  FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDT-ERRFAQGSSLSFAAVDR 92

Query: 454 NVTLSDSGVVTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVER-FSTLNVREGEPVVLN 511
              L DSG   CVAR+  +GE A     +   K     P  ++   S   ++    V L 
Sbjct: 93  ---LQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               G P P   W +DG P + + +           L +  A    +  Y C A +  G 
Sbjct: 150 CHIDGHPRPTYQWFRDGTP-LSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQ 208

Query: 572 TAT 574
             +
Sbjct: 209 ACS 211



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 24/68 (35%), Positives = 33/68 (48%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            GDPK  ++W      ++ +     MH F   +L +  V PEDSG YTC A N      T 
Sbjct: 617  GDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTE 676

Query: 1798 STLFVQSK 1805
            + L+V  K
Sbjct: 677  APLYVVDK 684



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 4/67 (5%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE-QTGDVSLLIKQIGPGDEGE 143
           QG  A  + + +G+P P++ W + K  +++  K   R +  Q G  SL+I  + P D G 
Sbjct: 605 QGHTALLQCEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNG--SLVIHDVAPEDSGR 661

Query: 144 YTCTARN 150
           YTC A N
Sbjct: 662 YTCIAGN 668



 Score = 39.1 bits (87), Expect = 0.39
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + +G TA   C     GDP   ++W   +++++ +    + H F   S+ I  V  ED G
Sbjct: 603  VYQGHTALLQCEA--QGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG 660

Query: 2448 VYMCRASN 2455
             Y C A N
Sbjct: 661  RYTCIAGN 668



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 6/90 (6%)

Query: 3982 QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKP-LLHKNRFTP-IYDFGYVAMNFGWVY 4039
            +T++ +  T   +C+    GDP   ++W   GK  +L   +  P ++ F   ++    V 
Sbjct: 600  RTTVYQGHTALLQCEAQ--GDPKPLIQW--KGKDRILDPTKLGPRMHIFQNGSLVIHDVA 655

Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            PEDSG Y C A N   +  T+A +    KP
Sbjct: 656  PEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGK 2952
            A LA  RR  V  T    P W+     + QL EG+  +L+   +    P   + WY N  
Sbjct: 394  ANLAGQRRQDVNITVATVPSWLKK-PQDSQLEEGKPGYLDCLTQATPKPT--VVWYRNQM 450

Query: 2953 VLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            ++ + SRF++  + G + ++ V+VY  D   Y C +    G     + V    K
Sbjct: 451  LISEDSRFEVFKN-GTLRINSVEVY--DGTWYRCMSSTPAGSIEAQARVQVLEK 501



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V +G      C   G P P + W   DR I D       ++   N +L+I +V   DSG 
Sbjct: 603 VYQGHTALLQCEAQGDPKPLIQWKGKDR-ILDPTKLGPRMHIFQNGSLVIHDVAPEDSGR 661

Query: 463 VTCVARNKSGETAFQCRLNVIEK 485
            TC+A N       +  L V++K
Sbjct: 662 YTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 62/285 (21%), Positives = 99/285 (34%), Gaps = 18/285 (6%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E  P + +     A             + G+P P   W R   PL +       +   + 
Sbjct: 125 EAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQS---NHTVSSK 181

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS----VYIQPEGXXXXXXXXXXXXXYRHVS 183
           + +L ++  GP   G Y+C A + +G+A  S    + I  E               R+  
Sbjct: 182 ERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARY-E 240

Query: 184 ETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
           E + H  +  Q   + Q     +   TN +         V      LL +V  R +   R
Sbjct: 241 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR 300

Query: 244 YVGESD--VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWF 300
            +G+      I  E    L  +    + + PR      G++ +   +   G P P V W 
Sbjct: 301 CIGQGQRGPPIILEATLHLAEIEDMPLFE-PR--VFTAGSEERVTCLPPKGLPEPSVWWE 357

Query: 301 KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             G RL     H  +    H  L + N  +SD+G YT  A N  G
Sbjct: 358 HAGVRL---PTHGRVYQKGH-ELVLANIAESDAGVYTCHAANLAG 398



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E  GD    ++W    R ++ +        F   +L I  V   D+G YTC A N+    
Sbjct: 614  EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 994  TTSANLTIVTKKDIIAESQHPG 1015
             T A L +V  K +  ES+ PG
Sbjct: 674  HTEAPLYVV-DKPVPEESEGPG 694



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 21/77 (27%), Positives = 37/77 (48%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           E  GDP   I+W    + ++ +     +  F   SL +  +  +DSG YTC A ++  + 
Sbjct: 614 EAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIK 673

Query: 721 ETKAVLHVTPRATIERT 737
            T+A L+V  +   E +
Sbjct: 674 HTEAPLYVVDKPVPEES 690



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 17/125 (13%)

Query: 1288 IQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHL-----ECRLQPVGDQTM 1342
            +  L+D+       R+D+T  +A + + A  NI+ +E   V L     E  +QP    T+
Sbjct: 90   VDRLQDSGTFQCVARDDVTGEEA-RSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTL 148

Query: 1343 RV----------EWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            R           +WF +G P+  G         +   L L    PE SG+Y+C A +  G
Sbjct: 149  RCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFG 207

Query: 1393 EAVTS 1397
            +A +S
Sbjct: 208  QACSS 212



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 11/128 (8%)

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
            R  C + PK  P+  + W   G  LP+  R   VY  G   L +  +   D+G Y C A 
Sbjct: 340  RVTC-LPPKGLPEPSVWWEHAGVRLPTHGR---VYQKGH-ELVLANIAESDAGVYTCHAA 394

Query: 3908 NDFGEDFTKATISCKKLPDIILQ---NQVPRGMK-RSEALTQM--EATIKKYTSEVYLTE 3961
            N  G+      I+   +P  + +   +Q+  G     + LTQ   + T+  Y +++ ++E
Sbjct: 395  NLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISE 454

Query: 3962 DDLYDVDK 3969
            D  ++V K
Sbjct: 455  DSRFEVFK 462



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 1/95 (1%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            Q E + DP   I+W    ++L+          F   +L + DV   DSG YTC A N   
Sbjct: 612  QCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNL 3028
               T + +Y   K  + E ++ P      + IQ +
Sbjct: 672  IKHTEAPLYVVDKP-VPEESEGPGSPPPYKMIQTI 705



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 5/62 (8%)

Query: 1738 GDPKLRVEWLRNGVPIE--ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G P+   +W R+G P+    SN   +  +     L ++   PE SG Y+C A +  G+A 
Sbjct: 154  GHPRPTYQWFRDGTPLSDGQSNHTVSSKERN---LTLRPAGPEHSGLYSCCAHSAFGQAC 210

Query: 1796 TS 1797
            +S
Sbjct: 211  SS 212



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGK---PIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
            +G    L+C  Q  GD    ++W    +   P K G R    + F   +L +  V PEDS
Sbjct: 605  QGHTALLQCEAQ--GDPKPLIQWKGKDRILDPTKLGPRM---HIFQNGSLVIHDVAPEDS 659

Query: 1381 GVYTCQATNQLGEAVTSCALRVIAK 1405
            G YTC A N      T   L V+ K
Sbjct: 660  GRYTCIAGNSCNIKHTEAPLYVVDK 684



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++  P+   H  S  ++     V L   ++    P    +WF++G  L+ G +   T   
Sbjct: 124  IEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTY--QWFRDGTPLSDG-QSNHTVSS 180

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                L++     + SG+Y+C A +  G+A S+ +  +
Sbjct: 181  KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +W +DG P+       T  +     LT++      +G Y+C A++A GQA +S N T+
Sbjct: 161  QWFRDGTPLSDGQSNHTVSSKER-NLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTL 217


>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
          Length = 1187

 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 100/437 (22%), Positives = 175/437 (40%), Gaps = 52/437 (11%)

Query: 4387 TTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQAR---FEVEFDGEPLPLIK 4443
            T  I+ K     +V+       +PP F          E  +      E   +G P P+I 
Sbjct: 232  TQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIY 291

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            W +E+  +  +    ++    K++ II  V   DS  +  +A+N  G    + ++ V+  
Sbjct: 292  WAKEDGMLPKNRT--VYKNFEKTLQIIH-VSEADSGNYQCIAKNALGAIHHTISVRVK-- 346

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNK 4561
                      P +    QN+ ++ G+   L  +  G     + WL NG  ++  PD  ++
Sbjct: 347  --------AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSR 398

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
             ++ D   T++      + S  Y+C A N  G    +A   V++ A              
Sbjct: 399  KIDGD---TIIFSNVQERSSAVYQCNASNEYGYLLANA--FVNVLAE------------- 440

Query: 4622 PPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            PP I+ P     +++A   A+   C   G PLPT++W+KG K    + +  +    +  T
Sbjct: 441  PPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAK--GSALHEDIYVLHENGT 497

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739
            L I  A  +  G Y CVA N  G       L++         P        VV  G    
Sbjct: 498  LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYA-----VVQRGSMVS 552

Query: 4740 FKTQI--TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
            F+ ++     +  T+ WL++   +P    F +    +   L++ +  ++D+GT+TC A T
Sbjct: 553  FECKVKHDHTLSLTVLWLKDNRELPSDERFTV----DKDHLVVADVSDDDSGTYTCVANT 608

Query: 4798 AAGQVETSAKLVVKSKT 4814
                V  SA L V + T
Sbjct: 609  TLDSVSASAVLSVVAPT 625



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 88/408 (21%), Positives = 162/408 (39%), Gaps = 35/408 (8%)

Query: 4409 KPPIFTKKMQPCRVFE-HEQARFEVEFDGEPLPLIKWYRE--NFPIKNSPDFQIHTFS-T 4464
            +PP  T++     + +  E    + E  G+P P   W R   +F I   P   +   + T
Sbjct: 51   QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 110

Query: 4465 KSILIIRQVFVED-SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA-QN 4522
              I I+ +   E    V+   A N  G A  S N+VV   R         P +T    + 
Sbjct: 111  LIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVRPSRS--------PLWTKEKLEP 161

Query: 4523 VNVTSGQLVRLDTKVT-GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            + + SGQ + L  +   G  P  ++W+ N  +  P  +++ + +     L      P+D+
Sbjct: 162  ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLP--QSERVSQGLNGDLYFSNVLPEDT 219

Query: 4582 GK-YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
             + Y C A  +  +     +  +S+     K   +       PE     K+++   G  +
Sbjct: 220  REDYICYARFNHTQT-IQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEEL--RGNVL 276

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
               C   G P P + W K D ++  ++    +    E TL+I      D G+Y+C+A N+
Sbjct: 277  SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF---EKTLQIIHVSEADSGNYQCIAKNA 333

Query: 4701 AGRV--TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
             G +  T++ ++K            +T  +++V+  G+      +     KP I WL  G
Sbjct: 334  LGAIHHTISVRVKAAP-------YWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 386

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
              I   PD     + +   ++  N  E  +  + C A+   G +  +A
Sbjct: 387  VPIEIAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 433



 Score = 66.5 bits (155), Expect = 2e-09
 Identities = 64/238 (26%), Positives = 100/238 (42%), Gaps = 17/238 (7%)

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA---PQFV 395
           +++  NG +  S  L  E   E Y+   R  +    QQ++      IS K+     P F+
Sbjct: 201 VSQGLNGDLYFSNVLP-EDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFL 259

Query: 396 KV---CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
                  +++   G +   +C   G P P + W   D  +  +      V ++    L I
Sbjct: 260 TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRT----VYKNFEKTLQI 315

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNA 512
            +V+ +DSG   C+A+N  G  A    ++V  K    AP ++     L +  GE   L  
Sbjct: 316 IHVSEADSGNYQCIAKNALG--AIHHTISVRVK---AAPYWITAPQNLVLSPGEDGTLIC 370

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           RA G P PRI+W  +GVPI   P+       G  T+     +   +A YQC A N  G
Sbjct: 371 RANGNPKPRISWLTNGVPIEIAPDDPSRKIDG-DTIIFSNVQERSSAVYQCNASNEYG 427



 Score = 64.9 bits (151), Expect = 7e-09
 Identities = 53/200 (26%), Positives = 84/200 (42%), Gaps = 16/200 (8%)

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR---DDYNHK 439
           I +  KA AP ++   Q+  ++ G+     CR  G P P ++W  N   I    DD + K
Sbjct: 341 ISVRVKA-APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK 399

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           I         ++ +NV    S V  C A N+ G       +NV+ +     P+ +   +T
Sbjct: 400 I-----DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP----PRILTPANT 450

Query: 500 L-NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           L  V    P +L+    G+P P I W K       + ++ +  + G  TL+IP A+    
Sbjct: 451 LYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDST 508

Query: 559 AWYQCTAQNVAGSTATRARL 578
             Y C A+N  G       L
Sbjct: 509 GTYTCVARNKLGMAKNEVHL 528



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 72/318 (22%), Positives = 131/318 (41%), Gaps = 26/318 (8%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSIL 4468
            P I T      +V  +  A  +  F G PLP I+W++       +   + +H   T  I 
Sbjct: 442  PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIP 501

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            + ++   + +  +  VA N+ G AK   +L +++        +  P + +      V  G
Sbjct: 502  VAQK---DSTGTYTCVARNKLGMAKNEVHLEIKD----ATWIVKQPEYAV------VQRG 548

Query: 4529 QLVRLDTKV--TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             +V  + KV    T  + V WLK+ +++  D R  + ++D    L++ +    DSG Y C
Sbjct: 549  SMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV-DKD---HLVVADVSDDDSGTYTC 604

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            VA N+  ++   A  V+S+ A    P P     N PP  +E L D++    Q        
Sbjct: 605  VA-NTTLDS-VSASAVLSVVAPTPTPAPVYDVPN-PPFDLE-LTDQLDKSVQLSWTPGDD 660

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR--V 4704
               P+        D + KP  +   +  +   T       P     ++ +A NS G+   
Sbjct: 661  NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLNLSPYVNYSFRVMAVNSIGKSLP 720

Query: 4705 TVAAKLKVTQPDQADNLP 4722
            + A++  +T+  + D  P
Sbjct: 721  SEASEQYLTKASEPDKNP 738



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 47/181 (25%), Positives = 72/181 (39%), Gaps = 16/181 (8%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP   T    +  +   + A  + +    G     IEWF   K       I  ++  G  
Sbjct: 441  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 496

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEGLKDGQ 3165
             LEI   +   +GTY+C A NK G A+  V LE  D +   ++P +         ++ G 
Sbjct: 497  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAV-------VQRGS 549

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
               FEC V       + + W  + + +    R  TV     VV D++   + DSG Y C 
Sbjct: 550  MVSFECKVKHDHTLSLTVLWLKDNRELPSDERF-TVDKDHLVVADVS---DDDSGTYTCV 605

Query: 3226 A 3226
            A
Sbjct: 606  A 606



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 16/197 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RPP F T   +  +  E +        I  G  + +I W      +  +   RTVY    
Sbjct: 254  RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN---RTVYKNFE 310

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              L+I+     DSG Y C A N  G     ISV+++         P + T  QN+  L  
Sbjct: 311  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA-------PYWITAPQNLV-LSP 362

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+     C      +P  +I W  NG P+  +    +    G  ++  +  Q   S  Y 
Sbjct: 363  GEDGTLICRA--NGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQ 419

Query: 3224 CRAYNKYGEDFTRATIN 3240
            C A N+YG     A +N
Sbjct: 420  CNASNEYGYLLANAFVN 436



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V + G  + FEC V+     +L + W  +N+ LPS  R+    D   V+ D++   ++DS
Sbjct: 544  VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVS---DDDS 599

Query: 2844 GIYTCKATNSKGSATTSGSL 2863
            G YTC A  +  S + S  L
Sbjct: 600  GTYTCVANTTLDSVSASAVL 619



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 67/305 (21%), Positives = 110/305 (36%), Gaps = 21/305 (6%)

Query: 61  ITAGRPGEPSPPIF---EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNK 117
           + + +     PP F   E    N    +G     E    G PTP++ W ++   L + N+
Sbjct: 245 VISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPK-NR 303

Query: 118 YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXX 177
              +  E+T    L I  +   D G Y C A+N  G    ++ ++ +             
Sbjct: 304 TVYKNFEKT----LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLV 359

Query: 178 XYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFR 237
                  T+  +A G        S  T  V      D  S    K+D  +  +   V  R
Sbjct: 360 LSPGEDGTLICRANGNP--KPRISWLTNGVPIEIAPDDPSR---KIDG-DTIIFSNVQER 413

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGAD--AQFQVQLSGNPRP 295
            S   +    ++       +  +  ++ P     P N+  Q  A+  A       G+P P
Sbjct: 414 SSAVYQCNASNEYGYLL-ANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLP 472

Query: 296 RVTWFKNGQRLINSNKHE-IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLA 354
            + WFK  +    S  HE I   H + TL +   QK  +G YT +A N  G      +L 
Sbjct: 473 TIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 529

Query: 355 VESPT 359
           ++  T
Sbjct: 530 IKDAT 534



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 3/106 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V  AP +  A  N+    G +  L CR    G+   R+ W  NG PI+      P+ +
Sbjct: 343  VRVKAAPYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPD-DPSRK 399

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
             D   +   +V    S VY C A+N+ G  + +  + V+A+   IL
Sbjct: 400  IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRIL 445



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
            + +  P +++ P  + +  GE     CR  G+PKPR+ WL NG
Sbjct: 344  RVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 386



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 7/107 (6%)

Query: 1177 PVFVQPLSNPPPVSE--GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            P F+ P  N     E  G  + LEC  E  G PT  + W      +    + +T Y    
Sbjct: 256  PTFLTPEGNASNKEELRGNVLSLECIAE--GLPTPIIYWAKEDGMLP---KNRTVYKNFE 310

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281
              L IIH + AD+G Y   A N LG+ H +  VRV      +T  QN
Sbjct: 311  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN 357



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980
            ++ G    FE +++     +L V WLKD R + +  R T   +     L +  V+  D+G
Sbjct: 545  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 600

Query: 981  HYTCRAYNAIGQATTSANLTIV 1002
             YTC A   +   + SA L++V
Sbjct: 601  TYTCVANTTLDSVSASAVLSVV 622



 Score = 41.5 bits (93), Expect = 0.073
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)

Query: 2356 LESAEPFKRPEIPEPVTRQRP-VFTQPLQNIDNIQE--GQTAHFDCRLIPVGDPTLKVEW 2412
            ++  +P     I    +R+RP  F  P  N  N +E  G     +C  I  G PT  + W
Sbjct: 235  IQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLEC--IAEGLPTPIIYW 292

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             + + ++  +  + K  +    ++ I HV + D G Y C A N LG
Sbjct: 293  AKEDGMLPKNRTVYKNFE---KTLQIIHVSEADSGNYQCIAKNALG 335



 Score = 41.1 bits (92), Expect = 0.096
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            AEPP+ +T    + +++  + A  +        P   +EWF   K           H+ G
Sbjct: 439  AEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG 496

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
               L+I    ++++G Y CVA NKLG    + +L+
Sbjct: 497  T--LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE 529



 Score = 40.7 bits (91), Expect = 0.13
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            +  G    FE +V+    L++TV W  + +++ S  R     D     L +A V  +DSG
Sbjct: 545  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 600

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
             YT VA         SA ++V
Sbjct: 601  TYTCVANTTLDSVSASAVLSV 621



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 41/159 (25%), Positives = 67/159 (42%), Gaps = 12/159 (7%)

Query: 3557 PPEFTTTPSDLI-LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            PP   T  + L  +  N  A  +C           +EWF   K       +  +++ G  
Sbjct: 441  PPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHENG-- 496

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ-- 3673
             LEI    +   G YTC A N+ G A     L++K    I+ +P+     +    S +  
Sbjct: 497  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSFECK 556

Query: 3674 -KLEETLHKREEITIED--EKPNPPRFTVEIKDNIDVPE 3709
             K + TL     + ++D  E P+  RFTV+ KD++ V +
Sbjct: 557  VKHDHTL-SLTVLWLKDNRELPSDERFTVD-KDHLVVAD 593



 Score = 39.9 bits (89), Expect = 0.22
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 4/86 (4%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PPR          V    P   DC     G P   I+WF   +  A    ++ L++ G  
Sbjct: 441  PPRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWFKGAKGSALHEDIYVLHENG-- 496

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSA 3779
             L+I        G YTC A NK G A
Sbjct: 497  TLEIPVAQKDSTGTYTCVARNKLGMA 522



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 3/102 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P + T P +L+LS        CR     +   R+ W  NG P+       +    G  I+
Sbjct: 349  PYWITAPQNLVLSPGEDGTLICRAN--GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 406

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
                V +R + +Y C A+N +G    +  + V      IL P
Sbjct: 407  -FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 447



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 43/170 (25%), Positives = 63/170 (37%), Gaps = 16/170 (9%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           DC   G P P + WF   +  +    H+ +     N  L I       +G  TCVARNK 
Sbjct: 463 DCAFFGSPLPTIEWF---KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 519

Query: 472 GETAFQCRLNVIEKEQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTPRIT--WQKDG 528
           G    +  L + +   +V  P++        V+ G  V    +     T  +T  W KD 
Sbjct: 520 GMAKNEVHLEIKDATWIVKQPEYAV------VQRGSMVSFECKVKHDHTLSLTVLWLKDN 573

Query: 529 VPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +P+ E R   D     L +      D+  Y C A     S +  A L
Sbjct: 574 RE-LPSDE-RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVL 619



 Score = 39.5 bits (88), Expect = 0.29
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            IEWFK          +    + G  TL I   + D +G YTC A N LG A +   ++I+
Sbjct: 474  IEWFKGAKGSALHEDIYVLHENG--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 531

Query: 2736 DRHWLL 2741
            D  W++
Sbjct: 532  DATWIV 537



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           P I +Q  K+       N   + + +G P P  SWTR            +     TG + 
Sbjct: 53  PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 112

Query: 131 LLIKQIGPGD--EGEYTCTARNQYGEAIC-SVYIQP 163
           + I   G  +  EG Y CTARN+ G A+  ++ ++P
Sbjct: 113 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRP 148



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 8/100 (8%)

Query: 3829 PPKFIT-QIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            PP F+T +  +   EE  G  +  EC  E    P   I W +   +LP     RTVY   
Sbjct: 255  PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPI--IYWAKEDGMLPKN---RTVYKNF 309

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              +L I++V   DSG Y C A N  G      ++  K  P
Sbjct: 310  EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 349



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G+PK R+ WL NGVPIE +    +    G   +    V    S  Y C A NE G
Sbjct: 374  GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYG 427



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + PR +T  N   ++   + A  +C     P P   +EW+   K           ++ G 
Sbjct: 440  EPPRILTPANTLYQVIANRPALLDCAFFGSPLPT--IEWFKGAKGSALHEDIYVLHENG- 496

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
              L+I     + +G YTC A N LG A + + L ++    I++  ++
Sbjct: 497  -TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEY 542



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-YRTTHDFGYV 2167
            P  LT   +L  +     A  +C       P  TI+WF  G K  A H      H+ G  
Sbjct: 442  PRILTPANTLYQVIANRPALLDCAF--FGSPLPTIEWF-KGAKGSALHEDIYVLHENG-- 496

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L+I     + +GTY C A NKLG A N   L++
Sbjct: 497  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI 530



 Score = 38.3 bits (85), Expect = 0.68
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1589 IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSG 1648
            ++ G    FE ++      +L V W  +N+ L S  RFT   +   V  D+     +DSG
Sbjct: 545  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSD---DDSG 600

Query: 1649 TYTCRAINALGEAVTSGIAIV 1669
            TYTC A   L     S +  V
Sbjct: 601  TYTCVANTTLDSVSASAVLSV 621



 Score = 37.9 bits (84), Expect = 0.90
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            ++ G    FEC+V+  +   LT+ W  + +++ +  R+    D   VA D+     +DSG
Sbjct: 545  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DV---SDDDSG 600

Query: 2181 TYMCKATNKLGEAVNTCTLKV 2201
            TY C A   L     +  L V
Sbjct: 601  TYTCVANTTLDSVSASAVLSV 621



 Score = 37.5 bits (83), Expect = 1.2
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
            V  G  V FECK++     +L V W K+ + +    RF    D   VA D+ D   +DSG
Sbjct: 545  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVA-DVSD---DDSG 600

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTT 1540
             YTC A   + +   S  L+  + T
Sbjct: 601  TYTCVANTTLDSVSASAVLSVVAPT 625



 Score = 37.1 bits (82), Expect = 1.6
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G+ V  EC+++     ++ V W  + + + +  RF      D   L +  V  +DSG YT
Sbjct: 548  GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 603

Query: 1385 CQATNQLGEAVTSCALRVIA 1404
            C A   L     S  L V+A
Sbjct: 604  CVANTTLDSVSASAVLSVVA 623



 Score = 36.7 bits (81), Expect = 2.1
 Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 3/104 (2%)

Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           S +    + P F+ P  +    +E R      +      PT  + W K+   +  +  + 
Sbjct: 247 SAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 306

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
             F     +L I+H+   D+G+Y   A N LG    T S+RV A
Sbjct: 307 KNFE---KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 347



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            +  G    +EC+++     ++ V W  + + L S  R+    D     L +  V  +DSG
Sbjct: 545  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSG 600

Query: 1916 EYTCKAINNLGQAVSSIRLNV 1936
             YTC A   L    +S  L+V
Sbjct: 601  TYTCVANTTLDSVSASAVLSV 621



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)

Query: 406 GKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV-V 463
           G+     CR   G P P + W  N  Q R   + +  V++  N  L  +NV   D+    
Sbjct: 167 GQSLVLPCRPPIGLPPPIIFWMDNSFQ-RLPQSER--VSQGLNGDLYFSNVLPEDTREDY 223

Query: 464 TCVARNKSGETAFQCR---LNVI--EKEQVVAPKFVERFSTLNVRE---GEPVVLNARAV 515
            C AR    +T  Q +   + VI  +  +   P F+      + +E   G  + L   A 
Sbjct: 224 ICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE 283

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
           G PTP I W K+   +   P+ R        TL I     +D+  YQC A+N  G+
Sbjct: 284 GLPTPIIYWAKEDGML---PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA 336



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 1039 ITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            + + PR L P     +++  + A  +      S L  T+EW+   K       I   H+ 
Sbjct: 438  LAEPPRILTPANTLYQVIANRPALLDCAFFG-SPLP-TIEWFKGAKGSALHEDIYVLHEN 495

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            G   L+I   + + +G YT VARN  G A+    + ++
Sbjct: 496  G--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 531



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDIL 3892
            + Q +   V+    V FEC+V+      L + W ++ + LPS  R+    D     L + 
Sbjct: 537  VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVA 592

Query: 3893 YVYAEDSGEYICRA 3906
             V  +DSG Y C A
Sbjct: 593  DVSDDDSGTYTCVA 606



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q G    F+C++      +L V W ++ + +    R T   D     + ++ V D+D G
Sbjct: 545  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVADVSDDDSG 600

Query: 2448 VYMCRASNLL 2457
             Y C A+  L
Sbjct: 601  TYTCVANTTL 610



 Score = 35.5 bits (78), Expect = 4.8
 Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 10/118 (8%)

Query: 378 ETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT--WFINDRQIRDD 435
           + E  +EI +   A   VK  +   V  G M  F+C+V       +T  W  ++R++  D
Sbjct: 523 KNEVHLEIKD---ATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSD 579

Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
              +  V++  +H L++ +V+  DSG  TCVA       +    L+V+      AP +
Sbjct: 580 --ERFTVDK--DH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVY 632



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 651 GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYT 710
           G  + FE +++     ++ + WLK+ + + +  RFT         L +  ++  DSG YT
Sbjct: 548 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSGTYT 603

Query: 711 CRAVSATGVAETKAVLHV---TPR-ATIERTSQHPETLQYIQQLE 751
           C A +        AVL V   TP  A +      P  L+   QL+
Sbjct: 604 CVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 648



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%)

Query: 1706 VITQAPVFTMPMKDI-RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            V+ + P    P   + +V  N+ A  +      G P   +EW +          +  +H+
Sbjct: 437  VLAEPPRILTPANTLYQVIANRPALLDCAFF--GSPLPTIEWFKGAKGSALHEDIYVLHE 494

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
             G   L +     + +GTYTC A N+LG A
Sbjct: 495  NG--TLEIPVAQKDSTGTYTCVARNKLGMA 522



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 25/105 (23%), Positives = 45/105 (42%), Gaps = 6/105 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK-VEWFKNGQPVTIGHRFRPIHDFGYV 1502
            PR +T   ++  VI  +    +C       S L  +EWFK  +   +      +H+ G +
Sbjct: 442  PRILTPANTLYQVIANRPALLDCAF---FGSPLPTIEWFKGAKGSALHEDIYVLHENGTL 498

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
             + +     + +G YTC A N +G  +    L  +  T IV+  +
Sbjct: 499  EIPVAQ--KDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPE 541



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 7/110 (6%)

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVE-GQVLHLEGQVEPKNDPDLKIEWYFNG 2951
            AR   G   +    E     WI+    E+ +V+ G ++  E +V+  +   L + W  + 
Sbjct: 515  ARNKLGMAKNEVHLEIKDATWIVK-QPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDN 573

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + L    RF +  D     L + DV + DSG YTC A N   ++ ++S V
Sbjct: 574  RELPSDERFTVDKDH----LVVADVSDDDSGTYTCVA-NTTLDSVSASAV 618


>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
          Length = 1502

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 64/203 (31%), Positives = 93/203 (45%), Gaps = 13/203 (6%)

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTA 4675
            AA  PP  I+  KD+I   G+   F C+  G P P V W K  K +   ++   +   +A
Sbjct: 28   AAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87

Query: 4676 DEYTLRISE-AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI---- 4730
                LRI     P DE  Y+CVA NS G +TV AKL V + DQ   LP+  P  D+    
Sbjct: 88   GA-VLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQ---LPSGFPNIDMGPQL 143

Query: 4731 -VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
             VV   + A      +    P I W ++   +  +     I +  +  L I ++ E D G
Sbjct: 144  KVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQG 203

Query: 4790 TFTCRATTAAG-QVETSAKLVVK 4811
             + C AT +AG +  + A L V+
Sbjct: 204  KYECVATNSAGVRYSSPANLYVR 226



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 4/192 (2%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+F+K  +D+    G++  F C+ TG P P VTW    +++       I  +ES    L 
Sbjct: 33  PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92

Query: 452 ITNV-TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           I  + T  D  V  CVA+N  GE     +L V+ ++Q+ +  P          V      
Sbjct: 93  IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
            +   A G P P ITW KD +P+ P+          +  L I  ++ +D   Y+C A N 
Sbjct: 153 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNS 212

Query: 569 AG-STATRARLY 579
           AG   ++ A LY
Sbjct: 213 AGVRYSSPANLY 224



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 84/327 (25%), Positives = 135/327 (41%), Gaps = 26/327 (7%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
            G     +PP F K+ +         A F  +  G+P P + W ++   + NS  F+   F
Sbjct: 25   GGCAAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKV-NSQRFETIEF 83

Query: 4463 --STKSILIIRQVFV-EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
              S  ++L I+ +    D  V+  VA+N  G     A L V  + +   G    P+  + 
Sbjct: 84   DESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGF---PNIDMG 140

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             Q   V   +   +    +G    ++ W K+   V P   N  +++  +  L I  +   
Sbjct: 141  PQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEET 200

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D GKYECVA NSAG          S PA       +     AP   I P+  +I+  G  
Sbjct: 201  DQGKYECVATNSAGVR-------YSSPANLYVRVRRV----APRFSILPMSHEIMPGGN- 248

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY-KCVAY 4698
            +  +C  VG P+P V+W +G + + P     + R   E T        +D  +Y  CVA 
Sbjct: 249  VNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELT------DVKDSANYHPCVAM 302

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALT 4725
            +S G +   A++ V    +A   P +T
Sbjct: 303  SSLGVIEAVAQITVKSLPKAPGTPMVT 329



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 81/310 (26%), Positives = 130/310 (41%), Gaps = 39/310 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--T 322
           PP+  ++P++     G  A F  Q +G+P+PRVTW K G++ +NS + E I         
Sbjct: 32  PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKK-VNSQRFETIEFDESAGAV 90

Query: 323 LRVRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
           LR++  +   D   Y  +A+N  G I     L V                     RE + 
Sbjct: 91  LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTV--------------------LREDQL 130

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY-NHKI 440
                   + PQ   V + R  T        C  +G P PE+TWF +   +     N +I
Sbjct: 131 PSGFPNIDMGPQLKVVERTRTAT------MLCAASGNPDPEITWFKDFLPVDPSASNGRI 184

Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
               SG  AL I +   +D G   CVA N +G   +    N+  + + VAP+F     + 
Sbjct: 185 KQLRSG--ALQIESSEETDQGKYECVATNSAG-VRYSSPANLYVRVRRVAPRFSILPMSH 241

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
            +  G  V +   AVG+P P + W +    + P  ++ +    G + L++   K S A +
Sbjct: 242 EIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV----GRNVLELTDVKDS-ANY 296

Query: 561 YQCTAQNVAG 570
           + C A +  G
Sbjct: 297 HPCVAMSSLG 306



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 79/303 (26%), Positives = 122/303 (40%), Gaps = 19/303 (6%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP F    ++    SG++     + TG     V W K GKKV       I  ++    +L
Sbjct: 32   PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVL 91

Query: 4573 ILEAY--PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
             ++    P+D   YECVA NS GE    A+  V     +D+        +  P++     
Sbjct: 92   RIQPLRTPRDENVYECVAQNSVGEITVHAKLTV---LREDQLPSGFPNIDMGPQL----- 143

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
             K+V   +     C   G P P + W+K    + PS      +      L+I  +   D+
Sbjct: 144  -KVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQ 202

Query: 4691 GDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749
            G Y+CVA NSAG R +  A L V     A     L    +I+   G              
Sbjct: 203  GKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIM--PGGNVNITCVAVGSPM 260

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809
            P ++W+ +GA    TP+  M   G N + L     ++      C A ++ G +E  A++ 
Sbjct: 261  PYVKWM-QGA-EDLTPEDDM-PVGRNVLEL--TDVKDSANYHPCVAMSSLGVIEAVAQIT 315

Query: 4810 VKS 4812
            VKS
Sbjct: 316  VKS 318



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 10/189 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFG 3104
            PP F    KD + +S G++A +      TGD    + W   GK +  S R  T+      
Sbjct: 32   PPRFIKEPKDQIGVS-GRVASFVCQA--TGDPKPRVTWNKKGKKVN-SQRFETIEFDESA 87

Query: 3105 MVVLEILGTKTT-DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              VL I   +T  D   Y C A N  G+  +  KL  + +   Q P    +I     LK 
Sbjct: 88   GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLRED--QLPSGFPNIDMGPQLKV 145

Query: 3164 GQSAHFECTVVPVD-DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             +       +     +PD +I W+ +  P+  S     +       L I  ++  D G+Y
Sbjct: 146  VERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKY 205

Query: 3223 VCRAYNKYG 3231
             C A N  G
Sbjct: 206  ECVATNSAG 214



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 42/125 (33%), Positives = 54/125 (43%), Gaps = 9/125 (7%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL--NDFG 3751
            PPRF  E KD I V  G    F C+    GDP  R+ W   G+      R  T+  ++  
Sbjct: 32   PPRFIKEPKDQIGV-SGRVASFVCQA--TGDPKPRVTWNKKGKK-VNSQRFETIEFDESA 87

Query: 3752 FIALDIDYIYA-RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810
               L I  +   RD   Y C A N  G  T  AK+T    R+  L S  P    G ++K 
Sbjct: 88   GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLT--VLREDQLPSGFPNIDMGPQLKV 145

Query: 3811 LERGR 3815
            +ER R
Sbjct: 146  VERTR 150



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 41/119 (34%), Positives = 51/119 (42%), Gaps = 12/119 (10%)

Query: 3447 TDDPNLKVEWYWNGKSLKAGSRFRT--FCDFGFVILEISPTY-PEDSGEYLCRAYNNYGE 3503
            T DP  +V W   GK + +  RF T  F +    +L I P   P D   Y C A N+ GE
Sbjct: 57   TGDPKPRVTWNKKGKKVNS-QRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGE 115

Query: 3504 AVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP-PEFT 3561
                  + V  K  ++ E QLP G    ID    L+    T       A SGNP PE T
Sbjct: 116  ------ITVHAKLTVLREDQLPSGFP-NIDMGPQLKVVERTRTATMLCAASGNPDPEIT 167



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 54/245 (22%), Positives = 91/245 (37%), Gaps = 36/245 (14%)

Query: 229 RLLREVSFRESITKRYVGESDVQIS-TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQV 287
           R  R+ +  E + +  VGE  V    T +     P   P I   P+   ++    A    
Sbjct: 97  RTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLC 156

Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
             SGNP P +TWFK+   +  S  +  I       L++ +++++D G Y  +A N  G  
Sbjct: 157 AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAG-- 214

Query: 348 VTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407
                +   SP   YV+ +R                      +AP+F  +    ++  G 
Sbjct: 215 -----VRYSSPANLYVRVRR----------------------VAPRFSILPMSHEIMPGG 247

Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467
                C   G P P V W      +  + +  +     G + L +T+V    +    CVA
Sbjct: 248 NVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV-----GRNVLELTDVK-DSANYHPCVA 301

Query: 468 RNKSG 472
            +  G
Sbjct: 302 MSSLG 306



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 38/116 (32%), Positives = 51/116 (43%), Gaps = 11/116 (9%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F    KDQI +  G  A F    +  GD   RV W K G+ V +    T  F+   
Sbjct: 31   EPPRFIKEPKDQIGVS-GRVASFVC--QATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87

Query: 967  VA-LTIKSV-TVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020
             A L I+ + T  D   Y C A N++G+ T  A LT      ++ E Q P G   I
Sbjct: 88   GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLT------VLREDQLPSGFPNI 137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 38/117 (32%), Positives = 50/117 (42%), Gaps = 14/117 (11%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            + P+F +   +   V G      C  Q  GD   RV W   GK + +  RF    EFD  
Sbjct: 31   EPPRFIKEPKDQIGVSGRVASFVC--QATGDPKPRVTWNKKGKKVNS-QRFE-TIEFDES 86

Query: 1369 ALDLLSVYP----EDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
            A  +L + P     D  VY C A N +GE      + V AK  ++ E Q PSG   I
Sbjct: 87   AGAVLRIQPLRTPRDENVYECVAQNSVGE------ITVHAKLTVLREDQLPSGFPNI 137



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/84 (29%), Positives = 38/84 (45%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F +  K+     G  A F  +  G+P P V+W +K   +      ++ ++E  G V 
Sbjct: 32  PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVL 91

Query: 131 LLIKQIGPGDEGEYTCTARNQYGE 154
            +     P DE  Y C A+N  GE
Sbjct: 92  RIQPLRTPRDENVYECVAQNSVGE 115



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP F+  P       G  A F C+ TG PKPRV W   G   VN  R++
Sbjct: 32   PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKK-VNSQRFE 79



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 36/96 (37%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FG 1766
            + P F    KD      + A F  +    GDPK RV W + G  + +    T   D   G
Sbjct: 31   EPPRFIKEPKDQIGVSGRVASFVCQA--TGDPKPRVTWNKKGKKVNSQRFETIEFDESAG 88

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             V        P D   Y C A N +GE    + L V
Sbjct: 89   AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTV 124



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 7/119 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH--DFGY 1501
            PRF+  PK  +  + G+   F C  +   D   +V W K G+ V    RF  I   +   
Sbjct: 33   PRFIKEPKD-QIGVSGRVASFVC--QATGDPKPRVTWNKKGKKVN-SQRFETIEFDESAG 88

Query: 1502 VALDIIDL-IAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559
              L I  L    D  +Y C A N VG   V  +LT      +     N     Q++V+E
Sbjct: 89   AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVE 147



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 12/130 (9%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV-YD--MG 3885
            PP+FI + K           F C+     DPK R+ W + GK + S  R+ T+ +D   G
Sbjct: 32   PPRFIKEPKDQIGVSGRVASFVCQATG--DPKPRVTWNKKGKKVNS-QRFETIEFDESAG 88

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945
             V          D   Y C A N  GE    A ++      ++ ++Q+P G    +   Q
Sbjct: 89   AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLT------VLREDQLPSGFPNIDMGPQ 142

Query: 3946 MEATIKKYTS 3955
            ++   +  T+
Sbjct: 143  LKVVERTRTA 152



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 10/121 (8%)

Query: 770 PQFIR-PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGY 827
           P+FI+ P   +G    GR A F  Q T   DP  RV W K G+ + +    T  F+    
Sbjct: 33  PRFIKEPKDQIGV--SGRVASFVCQAT--GDPKPRVTWNKKGKKVNSQRFETIEFDESAG 88

Query: 828 VSLNIMHLRA-EDAGSYTVRAVNKLGEAISTASIRVAARSTVTA---DLGIPEQRRYIEK 883
             L I  LR   D   Y   A N +GE    A + V     + +   ++ +  Q + +E+
Sbjct: 89  AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148

Query: 884 T 884
           T
Sbjct: 149 T 149


>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
          Length = 1911

 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 64/203 (31%), Positives = 93/203 (45%), Gaps = 13/203 (6%)

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY--FQMSRTA 4675
            AA  PP  I+  KD+I   G+   F C+  G P P V W K  K +   ++   +   +A
Sbjct: 28   AAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87

Query: 4676 DEYTLRISE-AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI---- 4730
                LRI     P DE  Y+CVA NS G +TV AKL V + DQ   LP+  P  D+    
Sbjct: 88   GA-VLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQ---LPSGFPNIDMGPQL 143

Query: 4731 -VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
             VV   + A      +    P I W ++   +  +     I +  +  L I ++ E D G
Sbjct: 144  KVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQG 203

Query: 4790 TFTCRATTAAG-QVETSAKLVVK 4811
             + C AT +AG +  + A L V+
Sbjct: 204  KYECVATNSAGVRYSSPANLYVR 226



 Score = 85.4 bits (202), Expect = 5e-15
 Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 4/192 (2%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+F+K  +D+    G++  F C+ TG P P VTW    +++       I  +ES    L 
Sbjct: 33  PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92

Query: 452 ITNV-TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA--PKFVERFSTLNVREGEPV 508
           I  + T  D  V  CVA+N  GE     +L V+ ++Q+ +  P          V      
Sbjct: 93  IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
            +   A G P P ITW KD +P+ P+          +  L I  ++ +D   Y+C A N 
Sbjct: 153 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNS 212

Query: 569 AG-STATRARLY 579
           AG   ++ A LY
Sbjct: 213 AGVRYSSPANLY 224



 Score = 80.6 bits (190), Expect = 1e-13
 Identities = 84/327 (25%), Positives = 135/327 (41%), Gaps = 26/327 (7%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
            G     +PP F K+ +         A F  +  G+P P + W ++   + NS  F+   F
Sbjct: 25   GGCAAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKV-NSQRFETIEF 83

Query: 4463 --STKSILIIRQVFV-EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
              S  ++L I+ +    D  V+  VA+N  G     A L V  + +   G    P+  + 
Sbjct: 84   DESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGF---PNIDMG 140

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
             Q   V   +   +    +G    ++ W K+   V P   N  +++  +  L I  +   
Sbjct: 141  PQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEET 200

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D GKYECVA NSAG          S PA       +     AP   I P+  +I+  G  
Sbjct: 201  DQGKYECVATNSAGVR-------YSSPANLYVRVRRV----APRFSILPMSHEIMPGGN- 248

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY-KCVAY 4698
            +  +C  VG P+P V+W +G + + P     + R   E T        +D  +Y  CVA 
Sbjct: 249  VNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELT------DVKDSANYHPCVAM 302

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALT 4725
            +S G +   A++ V    +A   P +T
Sbjct: 303  SSLGVIEAVAQITVKSLPKAPGTPMVT 329



 Score = 80.2 bits (189), Expect = 2e-13
 Identities = 81/310 (26%), Positives = 130/310 (41%), Gaps = 39/310 (12%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--T 322
           PP+  ++P++     G  A F  Q +G+P+PRVTW K G++ +NS + E I         
Sbjct: 32  PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKK-VNSQRFETIEFDESAGAV 90

Query: 323 LRVRNTQKS-DSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
           LR++  +   D   Y  +A+N  G I     L V                     RE + 
Sbjct: 91  LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTV--------------------LREDQL 130

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY-NHKI 440
                   + PQ   V + R  T        C  +G P PE+TWF +   +     N +I
Sbjct: 131 PSGFPNIDMGPQLKVVERTRTAT------MLCAASGNPDPEITWFKDFLPVDPSASNGRI 184

Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
               SG  AL I +   +D G   CVA N +G   +    N+  + + VAP+F     + 
Sbjct: 185 KQLRSG--ALQIESSEETDQGKYECVATNSAG-VRYSSPANLYVRVRRVAPRFSILPMSH 241

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
            +  G  V +   AVG+P P + W +    + P  ++ +    G + L++   K S A +
Sbjct: 242 EIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV----GRNVLELTDVKDS-ANY 296

Query: 561 YQCTAQNVAG 570
           + C A +  G
Sbjct: 297 HPCVAMSSLG 306



 Score = 77.8 bits (183), Expect = 9e-13
 Identities = 79/303 (26%), Positives = 122/303 (40%), Gaps = 19/303 (6%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP F    ++    SG++     + TG     V W K GKKV       I  ++    +L
Sbjct: 32   PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVL 91

Query: 4573 ILEAY--PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
             ++    P+D   YECVA NS GE    A+  V     +D+        +  P++     
Sbjct: 92   RIQPLRTPRDENVYECVAQNSVGEITVHAKLTV---LREDQLPSGFPNIDMGPQL----- 143

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
             K+V   +     C   G P P + W+K    + PS      +      L+I  +   D+
Sbjct: 144  -KVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQ 202

Query: 4691 GDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749
            G Y+CVA NSAG R +  A L V     A     L    +I+   G              
Sbjct: 203  GKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIM--PGGNVNITCVAVGSPM 260

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809
            P ++W+ +GA    TP+  M   G N + L     ++      C A ++ G +E  A++ 
Sbjct: 261  PYVKWM-QGA-EDLTPEDDM-PVGRNVLEL--TDVKDSANYHPCVAMSSLGVIEAVAQIT 315

Query: 4810 VKS 4812
            VKS
Sbjct: 316  VKS 318



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 10/189 (5%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFG 3104
            PP F    KD + +S G++A +      TGD    + W   GK +  S R  T+      
Sbjct: 32   PPRFIKEPKDQIGVS-GRVASFVCQA--TGDPKPRVTWNKKGKKVN-SQRFETIEFDESA 87

Query: 3105 MVVLEILGTKTT-DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              VL I   +T  D   Y C A N  G+  +  KL  + +   Q P    +I     LK 
Sbjct: 88   GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLRED--QLPSGFPNIDMGPQLKV 145

Query: 3164 GQSAHFECTVVPVD-DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
             +       +     +PD +I W+ +  P+  S     +       L I  ++  D G+Y
Sbjct: 146  VERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKY 205

Query: 3223 VCRAYNKYG 3231
             C A N  G
Sbjct: 206  ECVATNSAG 214



 Score = 48.8 bits (111), Expect = 5e-04
 Identities = 42/125 (33%), Positives = 54/125 (43%), Gaps = 9/125 (7%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL--NDFG 3751
            PPRF  E KD I V  G    F C+    GDP  R+ W   G+      R  T+  ++  
Sbjct: 32   PPRFIKEPKDQIGV-SGRVASFVCQA--TGDPKPRVTWNKKGKK-VNSQRFETIEFDESA 87

Query: 3752 FIALDIDYIYA-RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810
               L I  +   RD   Y C A N  G  T  AK+T    R+  L S  P    G ++K 
Sbjct: 88   GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLT--VLREDQLPSGFPNIDMGPQLKV 145

Query: 3811 LERGR 3815
            +ER R
Sbjct: 146  VERTR 150



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 41/119 (34%), Positives = 51/119 (42%), Gaps = 12/119 (10%)

Query: 3447 TDDPNLKVEWYWNGKSLKAGSRFRT--FCDFGFVILEISPTY-PEDSGEYLCRAYNNYGE 3503
            T DP  +V W   GK + +  RF T  F +    +L I P   P D   Y C A N+ GE
Sbjct: 57   TGDPKPRVTWNKKGKKVNS-QRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGE 115

Query: 3504 AVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP-PEFT 3561
                  + V  K  ++ E QLP G    ID    L+    T       A SGNP PE T
Sbjct: 116  ------ITVHAKLTVLREDQLPSGFP-NIDMGPQLKVVERTRTATMLCAASGNPDPEIT 167



 Score = 46.4 bits (105), Expect = 0.003
 Identities = 54/245 (22%), Positives = 91/245 (37%), Gaps = 36/245 (14%)

Query: 229 RLLREVSFRESITKRYVGESDVQIS-TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQV 287
           R  R+ +  E + +  VGE  V    T +     P   P I   P+   ++    A    
Sbjct: 97  RTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLC 156

Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
             SGNP P +TWFK+   +  S  +  I       L++ +++++D G Y  +A N  G  
Sbjct: 157 AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAG-- 214

Query: 348 VTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407
                +   SP   YV+ +R                      +AP+F  +    ++  G 
Sbjct: 215 -----VRYSSPANLYVRVRR----------------------VAPRFSILPMSHEIMPGG 247

Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467
                C   G P P V W      +  + +  +     G + L +T+V    +    CVA
Sbjct: 248 NVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV-----GRNVLELTDVK-DSANYHPCVA 301

Query: 468 RNKSG 472
            +  G
Sbjct: 302 MSSLG 306



 Score = 43.2 bits (97), Expect = 0.024
 Identities = 38/116 (32%), Positives = 51/116 (43%), Gaps = 11/116 (9%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F    KDQI +  G  A F    +  GD   RV W K G+ V +    T  F+   
Sbjct: 31   EPPRFIKEPKDQIGVS-GRVASFVC--QATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87

Query: 967  VA-LTIKSV-TVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020
             A L I+ + T  D   Y C A N++G+ T  A LT      ++ E Q P G   I
Sbjct: 88   GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLT------VLREDQLPSGFPNI 137



 Score = 42.3 bits (95), Expect = 0.042
 Identities = 38/117 (32%), Positives = 50/117 (42%), Gaps = 14/117 (11%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            + P+F +   +   V G      C  Q  GD   RV W   GK + +  RF    EFD  
Sbjct: 31   EPPRFIKEPKDQIGVSGRVASFVC--QATGDPKPRVTWNKKGKKVNS-QRFE-TIEFDES 86

Query: 1369 ALDLLSVYP----EDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
            A  +L + P     D  VY C A N +GE      + V AK  ++ E Q PSG   I
Sbjct: 87   AGAVLRIQPLRTPRDENVYECVAQNSVGE------ITVHAKLTVLREDQLPSGFPNI 137



 Score = 41.9 bits (94), Expect = 0.055
 Identities = 25/84 (29%), Positives = 38/84 (45%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F +  K+     G  A F  +  G+P P V+W +K   +      ++ ++E  G V 
Sbjct: 32  PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVL 91

Query: 131 LLIKQIGPGDEGEYTCTARNQYGE 154
            +     P DE  Y C A+N  GE
Sbjct: 92  RIQPLRTPRDENVYECVAQNSVGE 115



 Score = 40.3 bits (90), Expect = 0.17
 Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            PP F+  P       G  A F C+ TG PKPRV W   G   VN  R++
Sbjct: 32   PPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKK-VNSQRFE 79



 Score = 36.3 bits (80), Expect = 2.7
 Identities = 28/96 (29%), Positives = 36/96 (37%), Gaps = 4/96 (4%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FG 1766
            + P F    KD      + A F  +    GDPK RV W + G  + +    T   D   G
Sbjct: 31   EPPRFIKEPKDQIGVSGRVASFVCQA--TGDPKPRVTWNKKGKKVNSQRFETIEFDESAG 88

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
             V        P D   Y C A N +GE    + L V
Sbjct: 89   AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTV 124



 Score = 35.9 bits (79), Expect = 3.6
 Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 7/119 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH--DFGY 1501
            PRF+  PK  +  + G+   F C  +   D   +V W K G+ V    RF  I   +   
Sbjct: 33   PRFIKEPKD-QIGVSGRVASFVC--QATGDPKPRVTWNKKGKKVN-SQRFETIEFDESAG 88

Query: 1502 VALDIIDL-IAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559
              L I  L    D  +Y C A N VG   V  +LT      +     N     Q++V+E
Sbjct: 89   AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVE 147



 Score = 35.1 bits (77), Expect = 6.3
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 12/130 (9%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV-YD--MG 3885
            PP+FI + K           F C+     DPK R+ W + GK + S  R+ T+ +D   G
Sbjct: 32   PPRFIKEPKDQIGVSGRVASFVCQATG--DPKPRVTWNKKGKKVNS-QRFETIEFDESAG 88

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945
             V          D   Y C A N  GE    A ++      ++ ++Q+P G    +   Q
Sbjct: 89   AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLT------VLREDQLPSGFPNIDMGPQ 142

Query: 3946 MEATIKKYTS 3955
            ++   +  T+
Sbjct: 143  LKVVERTRTA 152



 Score = 34.7 bits (76), Expect = 8.3
 Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 10/121 (8%)

Query: 770 PQFIR-PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN-FGY 827
           P+FI+ P   +G    GR A F  Q T   DP  RV W K G+ + +    T  F+    
Sbjct: 33  PRFIKEPKDQIGV--SGRVASFVCQAT--GDPKPRVTWNKKGKKVNSQRFETIEFDESAG 88

Query: 828 VSLNIMHLRA-EDAGSYTVRAVNKLGEAISTASIRVAARSTVTA---DLGIPEQRRYIEK 883
             L I  LR   D   Y   A N +GE    A + V     + +   ++ +  Q + +E+
Sbjct: 89  AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148

Query: 884 T 884
           T
Sbjct: 149 T 149


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.316    0.133    0.391 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 712,439,094
Number of Sequences: 224733
Number of extensions: 32730650
Number of successful extensions: 325532
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 773
Number of HSP's successfully gapped in prelim test: 845
Number of HSP's that attempted gapping in prelim test: 203093
Number of HSP's gapped (non-prelim): 100106
length of query: 4814
length of database: 73,234,838
effective HSP length: 106
effective length of query: 4708
effective length of database: 49,413,140
effective search space: 232637063120
effective search space used: 232637063120
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 76 (34.7 bits)